WorldWideScience

Sample records for 10-year four-country nutrition

  1. A 10-year performance trajectory of top nutrition journals′ impact factors

    Directory of Open Access Journals (Sweden)

    Narges Jani

    2012-01-01

    Full Text Available Background and Aim: This study was performed to evaluate the impact factors (IFs and total citations of ISI-indexed nutrition journals in a 10-year period from 1999 to 2008 in order to assess the quality of nutrition journals. Materials and Methods: For this retrospective study, the IF and total citation data from 1998 to 2008 were collected through Journal Citation Reports of Thomson Scientific Corporation Web of Knowledge. We selected five highly cited journals in the "nutrition and dietetics" category for our analysis. These journals include Annual Reviews in Nutrition (ANNU REV NUTR, American Journal of Clinical Nutrition (AJCN, Progress in Lipid Research (PROG LIPID RES, Journal of Nutrition (J NUTR, and International Journal of Obesity (INT J OBESITY Results: All five selected journals were ranked as one of the top ten "nutrition and dietetics" journals between 1999 and 2008 in ISI database. Most of selected journals′ IF had an upward trend during the 10-year period with fluctuation in some cases. AJCN consistently received the greatest number of total citations during the study period, although its IF was not the highest among the five journals studied. Conclusion: The IF illustrated changes in relative rankings of five highly cited journals included in the "nutrition and dietetics" category of the Web of Knowledge. Rank according to the absolute number of citations received, however, did not correlate with rank according to IF.

  2. Maternal Prenatal Nutrition and Birth Outcomes on Malnutrition among 7- to 10-Year-Old Children: A 10-Year Follow-Up.

    Science.gov (United States)

    Zhou, Jing; Zeng, Lingxia; Dang, Shaonong; Pei, Leilei; Gao, Wenlong; Li, Chao; Yan, Hong

    2016-11-01

    To identify postnatal predictors of malnutrition among 7- to 10-year-old children and to assess the long-term effects of antenatal micronutrient supplementation on malnutrition. A follow-up study was conducted to assess the nutritional status of 7- to 10-year-olds (1747 children) whose mothers participated in a cluster-randomized double-blind controlled trial from 2002 to 2006. The rate of malnourished 7- to 10-year-olds was 11.1%. A mixed-effects logistic regression model adjusted for the cluster-sampling design indicated that mothers with low prepregnant midupper arm circumference had boys with an increased risk of thinness (aOR  2.05, 95% CI  1.11, 3.79) and girls who were more likely to be underweight (aOR 2.01, 95% CI 1.05, 3.85). Antenatal micronutrient supplementation was not significantly associated with malnutrition. Low birth weight was significantly associated with increased odds of malnutrition among boys (aOR 4.34, 95% CI 1.82, 10.39) and girls (aOR  7.50, 95% CI 3.48, 16.13). Being small for gestational age significantly increased the odds of malnutrition among boys (aOR 1.75, 95% CI 1.01, 3.04) and girls (aOR 4.20, 95% CI  2.39, 7.39). In addition, household wealth, parental height, being picky eater, and illness frequency also predicted malnutrition. Both maternal prenatal nutrition and adverse birth outcomes are strong predictors of malnutrition among early school-aged children. Currently, available evidence is insufficient to support long-term effects of antenatal micronutrient supplementation on children's nutrition. www.isrctn.com: ISRCTN08850194. Copyright © 2016 Elsevier Inc. All rights reserved.

  3. Children with nutritional rickets referred to hospitals in Copenhagen during a 10-year period

    DEFF Research Database (Denmark)

    Pedersen, Pernille; Michaelsen, K F; Mølgaard, C

    2003-01-01

    joints. Two children had generalized convulsions. None of the cases had received vitamin D supplementation. CONCLUSION: Nutritional rickets is still present among immigrants in Denmark, and it is likely that the prevalence of mild cases is high. Prevention through vitamin D supplementation is important...

  4. Nutritional status of schoolchildren aged 6 to 10 years in the city of Cruzeiro do Oeste - PR

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    Ana Paula de Oliveira

    2011-12-01

    Full Text Available Objective: To assess the nutritional status of schoolchildren. Methods: Data of the crosssectional study were obtained during the development of the “Project Educational Activities Related to School Process” in the city of Cruzeiro do Oeste-PR, Brazil. The study included children of both sexes enrolled in all six schools of the municipal network, in academic year 2010. We conducted anthropometric measurements of 1,074 schoolchildren aged 6 to 10 years. The variables assessed were weight and height to calculate BMI (Body MassIndex for classification according to criteria proposed by Cole et al. Results: According to the nutritional status, were found 5.1% (55 of children with low weight and a significant portion of overweight and obesity, 16.6% (178 and 9.8% (105, respectively, totaling 26, 4%(283 of schoolchildren with excess weight. There was no association between nutritional status of scholars and gender. BMI and age showed a direct relationship. Conclusion: The assessment of nutritional status in the schools surveyed points to, the nutritional transition, as a significant portion of the children was considered overweight and obese. It is noteworthy that the distribution between the different nutritional statuses did not differ between thesexes, but correlated with age; with increasing age, overweight also increases.

  5. Have the Answers to Common Legal Questions Concerning Nutrition Support Changed Over the Past Decade? 10 Questions for 10 Years.

    Science.gov (United States)

    Barrocas, Albert; Cohen, Michael L

    2016-06-01

    Clinical nutrition specialists (CNSs) are often confronted with technological, ethical, and legal questions, that is, what can be done technologically, what should be done ethically, and what must be done legally, which conflict at times. The conflict represents a "troubling trichotomy" as discussed in the lead article of this issue of Nutrition in Clinical Practice (NCP). During Clinical Nutrition Week in 2006, a symposium covering these 3 topics was presented, and later that year, an article covering the same topic was published in NCP In this article, we revisit several legal questions/issues that were raised 10 years ago and discuss current answers and approaches. Some of the answers remain unchanged. Other answers have been modified by additional legislation, court decisions, or regulations. In addition, new questions/issues have arisen. Some of the most common questions regarding nutrition support involve the following: liability, informed consent, medical decisional incapacity vs legal competence, advance directive specificity, surrogate decision making, physician orders for life-sustaining treatment and electronic medical orders for life-sustaining treatment, legal definition of death, patient vs family decision making, the noncompliant patient, and elder abuse obligations. In the current healthcare environment, these questions and issues are best addressed via a transdisciplinary team that focuses on function rather than form. The CNS can play a pivotal role in dealing with these challenges by applying the acronym ACT: being Accountable and Communicating with all stakeholders while actively participating as an integral part of the transdisciplinary Team.

  6. Association between the Family Nutrition and Physical Activity screening tool and cardiovascular disease risk factors in 10-year old children

    Science.gov (United States)

    Yee, Kimbo Edward

    Purpose. To examine the association of the Family Nutrition and Physical Activity (FNPA) screening tool, a behaviorally based screening tool designed to assess the obesogenic family environment and behaviors, with cardiovascular disease (CVD) risk factors in 10-year old children. Methods. One hundred nineteen children were assessed for body mass index (BMI), percent body fat (%BF), waist circumference (WC), total cholesterol, HDL-cholesterol, and resting blood pressure. A continuous CVD risk score was created using total cholesterol to HDL-cholesterol ratio (TC:HDL), mean arterial pressure (MAP), and WC. The FNPA survey was completed by parents. The associations between the FNPA score and individual CVD risk factors and the continuous CVD risk score were examined using correlation analyses. Results. Approximately 35% of the sample were overweight (19%) or obese (16%). The mean FNPA score was 24.6 +/- 2.5 (range 18 to 29). Significant correlations were found between the FNPA score and WC (r = -.35, pChildren from a high-risk, obesogenic family environment as indicated with a lower FNPA score have a higher CVD risk factor profile than children from a low-risk family environment.

  7. Nutritional status and phytate:zinc and phytate x calcium:zinc dietary molar ratios of lacto-ovo vegetarian Trappist monks: 10 years later.

    Science.gov (United States)

    Harland, B F; Smith, S A; Howard, M P; Ellis, R; Smith, J C

    1988-12-01

    A nutrition assessment of 16 members of a community of lacto-ovo vegetarian Trappist monks was conducted in 1977. Plasma zinc was found to be low-normal, which was attributed primarily to high intakes of phytate-containing foods. Individual and group counseling were instituted over a 10-year period in an attempt to emphasize the importance of wise food selection within the constraints of lacto-ovo vegetarianism. In 1987, a more comprehensive nutrition assessment of 21 members of the same community was performed. Food composites were analyzed, and 3-day instead of 24-hour dietary records were kept. Intakes of phytate-containing foods had decreased from 4,569 to 972 mg/day; intake of dietary zinc had increased from 7.4 to 9.7 mg/day; and the phytate:zinc molar ratio had decreased from 67 to 14 for the years 1977 and 1987, respectively. An analyzed phytate:zinc molar ratio of 9.8 and an analyzed phytate x calcium:zinc molar ratio of 0.3 were representative of the 1987 community. Both were within normal ranges. Plasma zinc had risen to upper-normal levels. The 1987 nutrition assessment showed that it is possible to be adequately nourished with a lacto-ovo vegetarian diet provided one has proper knowledge of the phytate-containing foods and the methods for compensating with foods of greater mineral density (primarily zinc).

  8. [Factors impacting the growth and nutritional status of cystic fibrosis patients younger than 10 years of age who did not undergo neonatal screening].

    Science.gov (United States)

    Hortencio, Taís Daiene Russo; Nogueira, Roberto José Negrão; Marson, Fernando Augusto de Lima; Hessel, Gabriel; Ribeiro, José Dirceu; Ribeiro, Antônio Fernando

    2015-01-01

    The aim of this study was to evaluate by clinical and laboratory parameters how cystic fibrosis (CF) affects growth and nutritional status of children who were undergoing CF treatment but did not receive newborn screening. A historical cohort study of 52 CF patients younger than 10 years of age were followed in a reference center in Campinas, Southeast Brazil. Anthropometric measurements were abstracted from medical records until March/2010, when neonatal screening program was implemented. Between September/2009 and March/2010, parental height of the 52 CF patients were also measured. Regarding nutritional status, four patients had Z-scores ≤ -2 for height/age (H/A) and body mass index/age (BMI/A). The following variables were associated with improved H/A ratio: fewer hospitalizations, longer time from first appointment to diagnosis, longer time from birth to diagnosis and later onset of respiratory disease. Forced vital capacity [FVC(%)], forced expiratory flow between 25-75% of FVC [FEF25-75(%)], forced expiratory volume in the first second [FEV1(%)], gestational age, birth weight and early respiratory symptoms were associated with IMC/A. Greater number of hospitalizations, diagnosis delay and early onset of respiratory disease had a negative impact on growth. Lower spirometric values, lower gestational age, lower birth weight, and early onset of respiratory symptoms had negative impact on nutritional status. Malnutrition was observed in 7.7% of cases, but 23% of children had nutritional risk. Copyright © 2014 Associação de Pediatria de São Paulo. Publicado por Elsevier Editora Ltda. All rights reserved.

  9. Association between blood cadmium levels and 10-year coronary heart disease risk in the general Korean population: the Korean National Health and Nutrition Examination Survey 2008-2010.

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    Jun-Pyo Myong

    Full Text Available BACKGROUND: Non-occupational heavy metals are considered risk factors for coronary heart disease (CHD. Several recent epidemiologic studies have evaluated the relationship between non-occupational cadmium exposure and risk factors for cardiovascular disease (CVD. This study was designed to investigate the relationship between non-occupational cadmium exposure and risk factors for CHD using the Framingham estimate of 10 year CHD risk. METHODS: The heavy metal dataset of the Korean National Health and Nutrition Examination Survey for 2008 through 2010, a cross-sectional survey of a representative sample of 4,668 non-institutionalized Koreans, was analyzed. Subjects were stratified into seven age groups to minimize the effects of age. The log-transformed blood cadmium concentrations were compared with the Framingham estimate of 10 year CHD risk in each age stratum. RESULTS: The Framingham estimate of 10 year CHD risk was significantly associated with the log-transformed blood cadmium concentrations (p<0.05 in all age groups of Korean men, with the lowest regression coefficient (0.254 for men aged 20 to <35 years and the highest (3.354 for men aged 55 to <60 years; similar results, however, were not observed in Korean women. After adjusting for survey year, age, and urinary cotinine concentration, the log-transformed blood cadmium levels among men aged 20 to <35, 40 to <45, 50 to <55, and 60 to <65 years were significantly associated with systolic blood pressure (p<0.05, but not with total and high density lipoprotein (HDL cholesterol concentrations. CONCLUSIONS: Cadmium exposure, even at non-occupational levels, may be associated with CHD risk in men. Despite the declines in non-occupational cadmium exposure over the past several decades, more efforts are needed.

  10. Global positioning system: A new tool to measure the distribution of anemia and nutritional status of children (5-10 years in a rural area in south India

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    N R Ramesh Masthi

    2012-01-01

    Full Text Available Global positioning system (GPS is a satellite-based navigation system that is of late being used in health care. Objectives: The aims of the study were to describe the geographical distribution and assess the prevalence of anemia and malnutrition in children aged 5-10 years with GPS. Subjects and Methods: This exploratory study was conducted over a period of 2 months in the rural field practice area of a medical college situated in Bangalore during June-July 2012. Children aged 5-10 years were the study subjects. Results: GPS was used for describing the geographical distribution of anemia and nutrition status on the Google earth map. The prevalence of anemia in the study subjects was 8.7%. The prevalence of underweight, stunting, thinness, and severe thinness among the study subjects was 52.8%, 28.5%, 23.5%, and 29.1%, respectively; however, overweight and obesity were observed only in 0.9% and 1.2% of the study subjects, respectively. Conclusion: GPS was easy to use and was able to demonstrate the actual distribution of morbidity at the household level in the rural area.

  11. The effect of long working hours on 10-year risk of coronary heart disease and stroke in the Korean population: the Korea National Health and Nutrition Examination Survey (KNHANES), 2007 to 2013

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    Lee, Dong-Wook; Hong, Yun-Chul; Min, Kyoung-Bok; Kim, Tae-Shik; Kim, Min-Seok; Kang, Mo-Yeol

    2016-01-01

    Background Recently, the emergence of long working hours and the associated conditions such as coronary heart disease (CHD) and stroke have gained attention. The aim of this study was to investigate the association between long working hours and the 10-year-risk of CHD and stroke, estimated by Jee’s health risk-appraisal model for ischemic heart disease. Methods We analyzed data from Koreans who randomly enrolled in Korean National Health and Nutrition Examination Survey 2008–2012 and finally...

  12. Compliance with the Swiss Society for Nutrition's dietary recommendations in the population of Geneva, Switzerland: a 10-year trend study (1999-2009).

    Science.gov (United States)

    de Abreu, Daisy; Guessous, Idris; Gaspoz, Jean-Michel; Marques-Vidal, Pedro

    2014-05-01

    The trends in compliance with the dietary recommendations of the Swiss Society for Nutrition in the Geneva population were assessed for the period from 1999 to 2009 using 10 cross-sectional, population-based surveys (Bus Santé study) with a total of 9,320 participants aged 35 to 75 years (50% women). Dietary intake was assessed using a self-administered, validated, semi-quantitative food frequency questionnaire. Trends were assessed by logistic regression adjusting for age, smoking status, education, and nationality using survey year as the independent variable. After excluding participants with extreme intakes, the percentage of participants with a cholesterol intake of trend=0.04) and from 57.8% to 61.4% in women (multivariate-adjusted P for trend=0.06). Calcium intake >1 g/day decreased from 53.3% to 46% in men and from 47.6% to 40.7% in women (multivariate-adjusted P for trendtrend<0.001). Conversely, no significant changes were observed for carbohydrates, protein, total fat (including saturated, monounsaturated, and polyunsaturated fatty acids), fiber, and vitamins D and A. We conclude that the quality of the Swiss diet did not improve between 1999 and 2009 and that intakes deviate substantially from expert recommendations for health promotion and chronic disease risk reduction. Copyright © 2014 Academy of Nutrition and Dietetics. Published by Elsevier Inc. All rights reserved.

  13. Building Mathematics Achievement Models in Four Countries Using TIMSS 2003

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    Wang, Ze; Osterlind, Steven J.; Bergin, David A.

    2012-01-01

    Using the Trends in International Mathematics and Science Study 2003 data, this study built mathematics achievement models of 8th graders in four countries: the USA, Russia, Singapore and South Africa. These 4 countries represent the full spectrum of mathematics achievement. In addition, they represent 4 continents, and they include 2 countries…

  14. Predicting Variations in Math Performancein Four Countries Using TIMSS

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    Daniel Koretz

    2001-09-01

    Full Text Available Although international comparisons of average student performance are a staple of U.S. educational debate, little attention has been paid to cross-national differences in the variability of performance. It is often assumed that the performance of U.S. students is unusually variable or that the distribution of U.S. scores is left-skewed – that is, that it has an unusually long ‘tail' of low-scoring students – but data from international studies are rarely brought to bear on these questions. This study used data from the Third International Mathematics and Science Study (TIMSS to compare the variability of performance in the U.S., Australia, France, Germany, Hong Kong, Korea, and Japan; investigate how this performance variation is distributed within and between classrooms; and explore how well background variables predict performance at both levels. TIMSS shows that the U.S. is not anomalous in terms of the amount, distribution, or prediction of performance variation. Nonetheless, some striking differences appear between countries that are potentially important for both research and policy. In the U.S., Germany, Hong Kong, and Australia, between 42 and 47 percent of score variance was between classrooms. At the other extreme, Japan and Korea both had less than 10 percent of score variance between classrooms. Two-level models (student and classroom were used to explore the prediction of performance by social background variables in four of these countries (the U.S., Hong Kong, France, and Korea. The final models included only a few variables; TIMSS lacked some important background variables, such as income, and other variables were dropped either because of problems revealed by exploratory data analysis or because of a lack of significance in the models. In all four countries, these sparse models predicted most of the between-classroom score variance (from 59 to 94 percent but very little of the within-classroom variance. Korea was the only

  15. [Oxaliplatin -- A 10-Year Trajectory].

    Science.gov (United States)

    Kanaji, Shingo; Oki, Eiji; Saeki, Hiroshi; Kitao, Hiroyuki; Maehara, Yoshihiko; Kakeji, Yoshihiro

    2016-06-01

    Oxaliplatin(Elplat(®)iv infusion solution)is a third-generation 1,2-DACH-platinum derivative. A number of international clinical trials have investigated the effects of this drug for each of its four indications. Building on the results of these earlier studies, much research has also been carried out in Japan in terms of developing and accumulating evidence on oxaliplatin. This report reviews the trajectory of its use over the last 10-years and considers its future potential.

  16. Swift: 10 Years of Discovery

    Science.gov (United States)

    The conference Swift: 10 years of discovery was held in Roma at La Sapienza University on Dec. 2-5 2014 to celebrate 10 years of Swift successes. Thanks to a large attendance and a lively program, it provided the opportunity to review recent advances of our knowledge of the high-energy transient Universe both from the observational and theoretical sides. When Swift was launched on November 20, 2004, its prime objective was to chase Gamma-Ray Bursts and deepen our knowledge of these cosmic explosions. And so it did, unveiling the secrets of long and short GRBs. However, its multi-wavelength instrumentation and fast scheduling capabilities made it the most versatile mission ever flown. Besides GRBs, Swift has observed, and contributed to our understanding of, an impressive variety of targets including AGNs, supernovae, pulsars, microquasars, novae, variable stars, comets, and much more. Swift is continuously discovering rare and surprising events distributed over a wide range of redshifts, out to the most distant transient objects in the Universe. Such a trove of discoveries has been addressed during the conference with sessions dedicated to each class of events. Indeed, the conference in Rome was a spectacular celebration of the Swift 10th anniversary. It included sessions on all types of transient and steady sources. Top scientists from around the world gave invited and contributed talks. There was a large poster session, sumptuous lunches, news interviews and a glorious banquet with officials attending from INAF and ASI. All the presentations, as well as several conference pictures, can be found in the conference website (http://www.brera.inaf.it/Swift10/Welcome.html). These proceedings have been collected owing to the efforts of Paolo D’Avanzo who has followed each paper from submission to final acceptance. Our warmest thanks to Paolo for all his work. The Conference has been made possible by the support from La Sapienza University as well as from the ARAP

  17. 10 YEARS AFTER NATO MEMBERSHIP

    DEFF Research Database (Denmark)

    10 years after NATO Membership. An Anniversary in the Shadow of a Crisis”, indeholder artikler fra politiske aktører, diplomater og forskere, der alle bidrog til til konferencen af samme navn, hvor den 10-året for baltisk medlemskab af NATO var omdrejningspunktet. Udover den danske...... forsvarsminister, er den estiske og litauiske forsvarsminister og NATO’s vicegeneralsekretær blandt bidragyderne. Konferencens formål var at fejre, inddrage og diskutere 10 års forsvarspolitisk NATO-samarbejde i Østersøområdet. Den internationale udvikling i Europa betød at konferencens dagsorden i stedet for kom...... billede af hvordan den russiske aggression på Krimhalvøen blev italesat af de repræsenterede landes Forsvarsministre samt fra hovedkvarteret i NATO. Konferencen blev afholdt tidligere i år i København, og var et resultat af et tæt samarbejde mellem Forsvarsakademiet, Forsvarsministeriet og ambassadørerne...

  18. The Anthropology of Online Search Strategy Formation: A Study of Four Countries.

    Science.gov (United States)

    Still, Julie

    1996-01-01

    Discusses the results of a survey sent to online searchers in four countries, the United Kingdom, the United States, Australia, and Canada, to investigate the influence of national culture on information retrieval skills. The survey form provided a sample question and asked searchers to prepare a preliminary search strategy in Sociological…

  19. Investigating the Psychometric Properties of the ACEI Global Guidelines Assessment (GGA) in Four Countries

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    Hardin, Belinda J.; Bergen, Doris; Hung, Hsuan-Fang

    2013-01-01

    The ACEI Global Guidelines Assessment (GGA) was developed to provide an international assessment tool that can be used by early childhood educators to develop, assess, and improve program quality worldwide. This pilot study was conducted in four countries to investigate the psychometric properties of the GGA within and across different countries.…

  20. Attracting and Integrating Newcomers into Church Life: Research in Four Countries

    Science.gov (United States)

    Sterland, Sam; Bellamy, John; Escott, Phillip; Castle, Keith

    2006-01-01

    This article highlights the importance of considering the flow of newcomers into church life and the inadequacy of relying solely upon changes in numbers of attenders in assessing the effectiveness of churches. Drawing upon data collected in four countries, Australia, England, New Zealand and the United States of America, this article looks at the…

  1. Cross-cultural validation of switching costs: a four-country assessment

    OpenAIRE

    El-Manstrly, Dahlia

    2014-01-01

    Purpose– The purpose of this paper is to develop a cross-cultural scale of customers’ perceived switching costs (PSCs). Customers’ PSCs function as a powerful defensive marketing tool that restrains customers from switching.Design/methodology/approach– Four sets of survey data were collected in the UK, Egypt, Germany, and China. An overall response rate of 86 percent was achieved across the four countries. Cross-cultural equivalence of the PSCs scale was assessed using multi-group confirmator...

  2. Sociological and psychological predictors of STD infection in homosexual men: a study of four countries.

    OpenAIRE

    Ross, M W

    1984-01-01

    I investigated over 600 homosexual men in four countries (Sweden, Finland, Ireland, and Australia) regarding the number of times they had contracted a sexually transmitted disease (STD) and several psychological variables including masculinity and feminity, sex role conservatism, relationships with parents, number of sexual partners, attitudes towards homosexuality, and involvement in the homosexual subculture. Using multiple linear regression in each country, it was found that 19-42% of the ...

  3. Cigarette purchase patterns in four countries and the relationship with cessation: findings from the International Tobacco Control (ITC) Four Country Survey.

    Science.gov (United States)

    Hyland, A; Laux, F L; Higbee, C; Hastings, G; Ross, H; Chaloupka, F J; Fong, G T; Cummings, K M

    2006-06-01

    Higher cigarette prices result in decreased cigarette consumption, but some smokers may seek lower-taxed cigarette sources. This price avoidance behaviour likely dampens the health impact of higher cigarette prices although it has not been thoroughly studied. To describe the characteristics of smokers who purchase low/untaxed cigarettes and to examine how this behaviour is associated with subsequent changes in smoking behaviours. Telephone survey data from 8930 smokers from the International Tobacco Control (ITC) Four Country Survey (ITC-4) were used to assess cigarette purchase patterns and smoking behaviours in Wave 1 conducted from October to December 2002 and subsequently followed seven months later in Wave 2. Respondents' smoking status, attempts to quit, amount smoked, and cigarette purchase patterns were assessed in both waves. Rates of purchase from a low/untaxed source at the respondents' last cigarette purchase differed notably between countries at Wave 1, from less than 1% in Australia to 15% in the United Kingdom. In the UK, but not the other countries, this increased significantly to 20% at Wave 2. Smokers who were older, white/English speakers, had higher incomes, and had higher levels of education were more likely to report purchasing cigarettes from a low/untaxed source on their last purchase. Those who reported purchasing from a low/untaxed source on their last purchase at Wave 1 were less likely to have tried to quit smoking quit smoking by Wave 2 (relative risk 0.70, p purchasers of low/untaxed cigarettes compared to purchasers of full-priced cigarettes. The availability of low/untaxed cigarettes may mitigate the influence of increases in cigarette prices.

  4. Consumers' cognitions with regard to genetically modified foods: Results of a qualitative study in four countries

    DEFF Research Database (Denmark)

    Bredahl, Lone

    1999-01-01

    -national differences, differences relating to different outcome groups considered, and differences relating to the presence or non-presence of genetically modified material in the end product. German and Danish results were generally more elaborate and revealed more complex cognitive structures than the results from...... Italy and the United Kingdom. In all four countries, however, genetic modification was associated with unnaturalness and low trustworthiness of the resulting product, independently of whether the genetically modified material was traceable in the product. Moral considerations were voiced as well...

  5. Health behaviours, knowledge, life satisfaction and wellbeing in people with mental illness across four countries and comparisons with normative sample

    Directory of Open Access Journals (Sweden)

    Natalie Parletta

    2016-08-01

    Full Text Available Background: People with chronic mental illness have poorer physical health and higher mortality than the general population. We investigated lifestyle factors in people with mental illness across four countries and compared with a normative sample. Design and methods: Data were collected from N=672 people (Germany, n=375; Palestine, n=192; London, n=63; Australia, n=42 with substance abuse disorder (n=224, schizophrenia (n=158, mood disorders (n=227 and somatoform disorders (n=63. The General Health Behaviour Questionnaire measured behaviours and knowledge related to nutrition, physical activity, alcohol, smoking, sleep, life satisfaction and wellbeing. The normative sample were derived from a German population (N=1,019. Data were analysed using ANOVAs and t-tests. Results: The Palestine sample did not differ from the Western samples on reported life satisfaction and wellbeing. However they reported unhealthier diets, less physical activity, and lower knowledge about the impact of diet, physical activity, smoking and sleep on health than the Western samples. Comparing the Western and normative samples, people with mental illness reported lower intake of healthy foods/drinks, higher intake of unhealthy foods, higher exercise, higher alcohol consumption, smoked less cigarettes, had less sleep and reported more sleep problems. Their knowledge was lower for nutrition, physical activity, and smoking. All participants reported lower life satisfaction and wellbeing than the normative sample (P values <0.001. Conclusions: Education on health-related lifestyle factors present important targets for primary care, quality of life and prevention of illness in people with mental illness. Further research will clarify specific predictors of health behaviours in each country.

  6. PBL – Reflections after 10 years

    DEFF Research Database (Denmark)

    Soler, José

    The poster describes course 34357 at DTU, where PBL has been used in the last 10 years. While the course responsibles where not aware initially that the used methodology was PBL, the poster describes the triggering idea for the initial taken choices, i.e. homogenize working methodologies for stud......The poster describes course 34357 at DTU, where PBL has been used in the last 10 years. While the course responsibles where not aware initially that the used methodology was PBL, the poster describes the triggering idea for the initial taken choices, i.e. homogenize working methodologies...

  7. 北京市丰台区8~10岁儿童碘营养现状及其影响因素分析%Nutritional status of iodine among children aged 8-10 years and its influencing factor in Fengtai District

    Institute of Scientific and Technical Information of China (English)

    石荣兴; 王军波; 赵建忠; 李志新; 张建军; 王会; 李洁; 芦然

    2011-01-01

    目的 了解丰台区8~10岁儿童碘营养流行病学特征和动态变化趋势,探讨影响碘营养状况的相关因素.方法 采用整群随机抽样方法,在丰台区按照东、西、南、北、中的方位抽取5所小学,每所学校再随机抽查8~10岁学生80名,进行尿碘检测、甲状腺触诊检查和自填式结构问卷调查.结果 丰台区儿章处于碘缺乏病消除状态.家用盐不含碘或含碘量过低、不食用海带等高碘食品、不喝牛奶等因素是碘缺乏的危险因素,过量食用海带等高碘食品是碘过量的危险因素.结论 应采取综合干预措施,使儿童碘营养保持在适宜的水平;适当调低人群食用碘盐的含碘值,注重食品碘的摄人.%Objective To understand the epidemic characteristic and changing tendency of8-to-10-year-old children's iodine nutrition condition in Fengtai district, and to discuss the relative factors that influence people's iodine nutrition conditions. Methods By using the method of cluster random sampling, five primary schools were chosen respectively from the positions of east, west, south, north and centre. Then 80 pupils aged 8 to 10 years were randomly recruited from each school. Urine iodine test, palpation of thyroid, and self-completing questionnaire were given to all the participants. Results The absenee or low level of iodine in salt, and never eating or eating too much high-iodine-containing food such as kelp, never drinking milk were risk factors of iodine deficiency. Conclusion The content of iodine in edible salt should be properly lowed. Comprehensive intervention measures to edible salt and food should be taken to keep the childrens iodine nutrition at a proper level.

  8. Lanthanum carbonate: safety data after 10years

    OpenAIRE

    Hutchison, Alastair

    2016-01-01

    Despite 10years of post-marketing safety monitoring of the phosphatebinder lanthanum carbonate, concerns about aluminium-like accumulationand toxicity persist. Here, we present a concise overview of the safety profileof lanthanum carbonate and interim results from a 5-year observationaldatabase study (SPD405-404; ClinicalTrials.gov identifier: NCT00567723). Thepharmacokinetic paradigms of lanthanum and aluminium are different inthat lanthanum is minimally absorbed and eliminated via the hepat...

  9. AMS at ANTARES - The first 10 years

    Science.gov (United States)

    Lawson, E. M.; Elliott, G.; Fallon, J.; Fink, D.; Hotchkis, M. A. C.; Hua, Q.; Jacobsen, G. E.; Lee, P.; Smith, A. M.; Tuniz, C.; Zoppi, U.

    2000-10-01

    The status and capabilities of the ANTARES AMS facility after 10 years are reviewed. The common AMS radioisotopes, 10Be, 14C, 26Al, 36Cl and 129I, are routinely analysed. A capability for the detection of 236U and other actinide isotopes has been developed. The measurement program includes support to Quaternary science projects at Australian universities and to ANSTO projects in global climate change and nuclear safeguards.

  10. Neurology--the next 10 years.

    Science.gov (United States)

    Baron, Ralf; Ferriero, Donna M; Frisoni, Giovanni B; Bettegowda, Chetan; Gokaslan, Ziya L; Kessler, John A; Vezzani, Annamaria; Waxman, Stephen G; Jarius, Sven; Wildemann, Brigitte; Weller, Michael

    2015-11-01

    Since the launch of our journal as Nature Clinical Practice Neurology in 2005, we have seen remarkable progress in many areas of neurology research, but what does the future hold? Will advances in basic research be translated into effective disease-modifying therapies, and will personalized medicine finally become a reality? For this special Viewpoint article, we invited a panel of Advisory Board members and other journal contributors to outline their research priorities and predictions in neurology for the next 10 years.

  11. Consumers' cognitions with regard to genetically modified foods: Results of a qualitative study in four countries

    DEFF Research Database (Denmark)

    Bredahl, Lone

    rankings of different beer and yoghurt products showed consistently low preferences for the genetically modified product alternatives across countries and product categories. Both in the case of yoghurt and beer, more traditional product alternatives were preferred. 5. In all four countries, genetic...... as unwholesome and untrustworthy, and a range of negative consequences were inferred, which would eventually prevent the attainment of individual life values such as happi and inner harmony, a long and healthy life, quality of life and security, and more social life values such as responsibility for nature...... were derived from the application of genetic engineering to produce beer and yoghurt, whereas a large palette of consequences were perceived in the three other countries. The results revealed no substantive differences in beliefs relating to the different outcome groups considered. 7. Overall...

  12. Information use skills in the engineering programme accreditation criteria of four countries

    Science.gov (United States)

    Bradley, Cara

    2014-01-01

    The need for twenty-first century information skills in engineering practice, combined with the importance for engineering programmes to meet accreditation requirements, suggests that it may be worthwhile to explore the potential for closer alignment between librarians and their work with information literacy competencies to assist in meeting accreditation standards and graduating students with high-level information skills. This article explores whether and how information use skills are reflected in engineering programme accreditation standards of four countries: Canada, the USA, the UK, and Australia. Results indicate that there is significant overlap between the information use skills required of students by engineering accreditation processes and librarians' efforts to develop information literacy competencies in students, despite differences in terms used to describe these skills. Increased collaboration between engineering faculty and librarians has the potential to raise student information literacy levels and fulfil the information use-related requirements of accreditation processes.

  13. Consumers' cognitions with regard to genetically modified foods. Results of a qualitative study in four countries.

    Science.gov (United States)

    Bredahl, L

    1999-12-01

    The objective of this research was to gain insight into consumers> attitudes towards genetic modification in food production. With means-end chain theory as the theoretical basis, laddering interviews were conducted with 400 consumers in Denmark, Germany, the United Kingdom and Italy. Perceived risks and benefits of genetic modification in foods were investigated using beer and yoghurt as examples. German and Danish responses revealed more complex cognitive structures than did the results from the United Kingdom and Italy. In all four countries, however, applying genetic modification was associated with unnaturalness and low trustworthiness of the resulting products, independently of whether the genetically modified material was traceable in the product. Moral considerations were voiced as well, as were a number of other consequences that were perceived to conflict with both individual and social values.

  14. Online Sexual Activity Experiences Among College Students: A Four-Country Comparison.

    Science.gov (United States)

    Döring, Nicola; Daneback, Kristian; Shaughnessy, Krystelle; Grov, Christian; Byers, E Sandra

    2015-12-10

    The purpose of this study was to compare male and female college students in four countries (Canada, Germany, Sweden, and the U.S.) on their lifetime experiences (prevalence) and frequency of recent experiences with six types of online sexual activities (OSA): sexual information, sexual entertainment, sexual contacts, sexual minority communities, sexual products, and sex work. Participants (N = 2690; M age, 24.65 years; 53.4 % women, 46.6 % men) were recruited from a university in each of the countries to complete an online survey that included background and demographic questions, and questions about OSA. Most participants reported experience with accessing sexual information (89.8 %) and sexual entertainment (76.5 %) online. Almost half (48.5 %) reported browsing for sexual products, and a substantial minority reported having engaged in cybersex (30.8 %). Very few participants (1.1 %) paid for online sexual services or received payment (0.5 %). In general, participants showed relatively infrequent experience with all types of OSA within the last 3 months. Men showed both higher prevalence and frequency of use of sexually stimulating material online than did women. However, this gender gap was smaller than in previous studies. Country and gender by country effects were (with one exception) either very small or non-existent, suggesting that, overall, students in the four countries were similar in their OSA experiences. Results are discussed in light of an emerging global net generation and globalized sexual culture.

  15. 10-year survival of total ankle arthroplasties

    Science.gov (United States)

    2011-01-01

    Background and purpose There is an ongoing need to review large series of total ankle replacements (TARs) for monitoring of changes in practice and their outcome. 4 national registries, including the Swedish Ankle Register, have previously reported their 5-year results. We now present an extended series with a longer follow-up, and with a 10-year survival analysis. Patients and methods Records of uncemented 3-component TARs were retrospectively reviewed, determining risk factors such as age, sex, and diagnosis. Prosthetic survival rates were calculated with exchange or removal of components as endpoint—excluding incidental exchange of the polyethylene meniscus. Results Of the 780 prostheses implanted since 1993, 168 (22%) had been revised by June 15, 2010. The overall survival rate fell from 0.81 (95% CI: 0.79–0.83) at 5 years to 0.69 (95% CI: 0.67–0.71) at 10 years. The survival rate was higher, although not statistically significantly so, during the latter part of the period investigated. Excluding the STAR prosthesis, the survival rate for all the remaining designs was 0.78 at 10 years. Women below the age of 60 with osteoarthritis were at a higher risk of revision, but age did not influence the outcome in men or women with rheumatoid arthritis. Revisions due to technical mistakes at the index surgery and instability were undertaken earlier than revisions for other reasons. Interpretation The results have slowly improved during the 18-year period investigated. However, we do not believe that the survival rates of ankle replacements in the near future will approach those of hip and knee replacements—even though improved instrumentation and design of the prostheses, together with better patient selection, will presumably give better results. PMID:22066551

  16. Mitochondrial ROS Metabolism: 10 Years Later.

    Science.gov (United States)

    Andreyev, A Y; Kushnareva, Y E; Murphy, A N; Starkov, A A

    2015-05-01

    The role of mitochondria in oxidative stress is well recognized, but many questions are still to be answered. This article is intended to update our comprehensive review in 2005 by highlighting the progress in understanding of mitochondrial reactive oxygen species (ROS) metabolism over the past 10 years. We review the recently identified or re-appraised sources of ROS generation in mitochondria, such as p66(shc) protein, succinate dehydrogenase, and recently discovered properties of the mitochondrial antioxidant system. We also reflect upon some controversies, disputes, and misconceptions that confound the field.

  17. Pediatric lung transplantation: 10 years of experience

    Science.gov (United States)

    Camargo, Priscila C. L. B.; Pato, Eduardo Z. S.; Campos, Silvia V.; Afonso, José E.; Carraro, Rafael M.; Costa, André N.; Teixeira, Ricardo H. O. B.; Samano, Marcos N.; Pêgo-Fernandes, Paulo M.

    2014-01-01

    Lung transplantation is a well-established treatment for advanced lung diseases. In children, the diseases that most commonly lead to the need for a transplantation are cystic fibrosis, pulmonary hypertension, and bronchiolitis. However, the number of pediatric lung transplantations being performed is low compared with the number of transplants performed in the adult age group. The objective of this study was to demonstrate our experience with pediatric lung transplants over a 10-year period in a program initially designed for adults. PMID:24860860

  18. Pediatric lung transplantation: 10 years of experience

    Directory of Open Access Journals (Sweden)

    Priscila C. L. B. Camargo

    2014-01-01

    Full Text Available Lung transplantation is a well-established treatment for advanced lung diseases. In children, the diseases that most commonly lead to the need for a transplantation are cystic fibrosis, pulmonary hypertension, and bronchiolitis. However, the number of pediatric lung transplantations being performed is low compared with the number of transplants performed in the adult age group. The objective of this study was to demonstrate our experience with pediatric lung transplants over a 10-year period in a program initially designed for adults.

  19. 10 years of the Medipix2 Collaboration

    CERN Document Server

    Campbell, Michael

    2011-01-01

    The Medipix2 Collaboration was started officially in September 1999 with the aim of disseminating hybrid pixel detector technology from High Energy Physics to other fields. The Collaboration was initially composed of 13 European research institutes. Over the ensuing 10 years the Collaboration expanded to reach a peak of 17 member institutes. Although our main scientific focus has been the development of the Medipix2 and Timepix single photon counting pixel detector readout chips the Collaboration members have expanded the range of applications for the technology to many more scientific fields than initially foreseen. We have signed a number of Technology Transfer Agreements during that time, most notably with PANalytical, whose commercially available PIXcel detector is based on the second version of the Medipix2 chip. This paper will review the history of the Collaboration covering as much as possible the main technical highlights. The success of the Collaboration is testimony to the willingness of a large nu...

  20. Sialolithiasis in a 10 year old child

    Directory of Open Access Journals (Sweden)

    Mohita Marwaha

    2012-01-01

    Full Text Available Sialolithiasis is often observed in the oral region, and is caused by the development of a calculus in the salivary gland or duct. This disease is mostly seen in adults or young adults, and seldom develops in children. Of all the cases of sialolithiasis, only 3% are seen in the pediatric population. The clinical presentation typically consists of a painful swelling of the involved salivary gland at meal times, as the obstruction is most acute at this time. The clinical signs often lead to an easy diagnosis. The salivary gland most commonly affected is the submandibular gland. In this paper, we have reported the case of a 10 year old female with sialolithiasis of the left submandibular duct. The treatment consisted of the use of lemon and orange drop candies, which stimulated the salivary flow and in turn resulted in the expulsion of stone.

  1. Food choice questionnaire revisited in four countries. Does it still measure the same?

    Science.gov (United States)

    Januszewska, Renata; Pieniak, Zuzanna; Verbeke, Wim

    2011-08-01

    This study focuses on the implementation of the food choice questionnaire (FCQ) across four countries. The first objective is to examine the degree to which the factor structure of the FCQ is invariant across different populations. The second objective is to analyse the motives for food choice in different countries. The cross-sectional sample of 1420 consumers consisted of Belgians (N=458), Hungarians (N=401), Romanians (N=229) and Filipinos (N=332). Data analyses included estimation of five multi-group confirmatory factor analysis models; calculation of mean importance ratings for each food choice factor across countries; ANOVA and Tukey post hoc tests; and a rank order test of most to least important factors within each country. The results confirm that the factorial structure of the FCQ is invariant with respect to factor configuration, factor loadings and item intercept. Sensory appeal is the most important factor among all European consumers, while health, convenience and price were all among the five most important factors shaping food choice in Belgium, Hungary and Romania. For Filipinos, the most important were health, price and mood. Sensory appeal ranked on the fourth place.

  2. Four country healthcare-associated infection prevalence survey: pneumonia and lower respiratory tract infections.

    LENUS (Irish Health Repository)

    Humphreys, H

    2010-03-01

    In 2006, the Hospital Infection Society was funded by the respective health services in England, Wales, Northern Ireland and the Republic of Ireland to conduct a prevalence survey of healthcare-associated infection (HCAI). Here, we report the prevalence of pneumonia and lower respiratory tract infection other than pneumonia (LRTIOP) in these four countries. The prevalence of all HCAIs was 7.59% (5743 out of 75 694). Nine hundred (15.7%) of these infections were pneumonia, and 402 (7.0%) were LRTIOP. The prevalence of both infections was higher for males than for females, and increased threefold from those aged <35 to those aged >85 years (P<0.001). At the time of the survey or in the preceding seven days, 23.7% and 18.2% of patients with pneumonia and LRTIOP, respectively, were mechanically ventilated compared to 5.2% of patients in the whole study population. Meticillin-resistant Staphylococcus aureus (MRSA) was the cause of pneumonia and LRTIOP in 7.6% and 18.1% of patients, respectively (P<0.001). More patients with LRTIOP (4.2%) had concurrent diarrhoea due to Clostridium difficile compared to patients with pneumonia (2.4%), but this did not reach statistical significance. Other HCAIs were present in 137 (15.2%) of patients with pneumonia and 66 (16.4%) of those with LRTIOP. The results suggest that reducing instrumentation, such as mechanical ventilation where possible, should help reduce infection. The higher prevalence of MRSA as a cause of LRTIOP suggests a lack of specificity in identifying the microbial cause and the association with C. difficile emphasises the need for better use of antibiotics.

  3. Public Health in Europe : 10 years EUPHA

    Directory of Open Access Journals (Sweden)

    Wilhelm Kirch

    2004-12-01

    Full Text Available

    What is Public Health (PH? What are the links between Public Health research and policy in Europe? Where is PH coming from in the 20th century and where is it directed to?

    These are some of the questions addressed by Public Health in Europe – 10 years EUPHA, the volume, edited by Prof.W. Kirch and published by Springer in 2004, that presents a selection of the manuscripts from the 10th Annual Congress of EUPHA, held in Dresden in 2002.

    Gunnar Tellness, the President of EUPHA, reminds us what PH is, or what it should be: the science devoted to reduce in the population the amount of disease, premature death and disease-related discomfort, sickness and disability.

    In addressing these themes,Tellness suggests to improve PH by employing healthpromoting and cultural activities, in order to establish strong collaborations between public agencies, private business, organisations and pioneers.

  4. Nutrition

    Science.gov (United States)

    ... for staff development or offered staff development on nutrition and dietary behavior to those who teach health education increased ... for staff development or offered staff development on nutrition and dietary behavior to those who teach health education increased ...

  5. 10-Year Observation of Bullous Pemphigoid Patients

    Directory of Open Access Journals (Sweden)

    Bengu Nisa Akay

    2010-06-01

    Full Text Available Background and Design: Bullous pemphigoid (BP is an autoimmune skin disorder characterized by large, tense blisters of the skin. It occurs mainly in the elderly. The one year mortality associated with bullous pemphigoid ranges from 19% to 41%. We aim to analyse the etiologic factors, demographic features, clinical course and response to treatment in patients with BP. Material and Method: Between January 1999 and January 2008, 31 patients with BP were evaluated retrospectively. We assessed duration of the disease, presence of associated symptoms, clinical findings, drug intake, response to treatment, recurrence rates and also extensive laboratory testing and radiologic evaluations on each patient to clarify a possible underlying malignancy. Results: In a 10-year period, 31 patients with BP, female male ratio was 19/12, ranging in age from 59 to 96 (mean 78.8±8.67 years were evaluated. Duration of the disease was 16.58±18.48 months. Direct immunoflourescence of the perilesional skin showed linear deposition of IgG and C3 along the dermoepidermal junction in 24 patients (77.4%. There was no significant relationship between drug usage and bullous pemphigoid. No malignancy was detected. Medium dosage of prednisolone (50-60 mg/day was the first choice of treatment in 8 patients with a complete response rate in all but two patients died during therapy. Four patients died during hospitalization with unknown reasons before any treatment was started. In 16 cases the initial treatment was prednisolone and azathioprine. The mean follow-up period was 12 months and 11 (35% cases had relapsed. The longest remission was achieved with prednisolone and azathioprine combination. Conclusion: In conclusion, no association was found between BP and drug usage or malignancy. All patients responded well to treatment. Therapy with prednisone maintained with azathiopyrine significantly reduced the recurrences. However, disease-specific mortality is found to be high and

  6. Attributable risks for acute myocardial infarction in four countries of Latin America

    Directory of Open Access Journals (Sweden)

    M. Ciruzzi

    2003-12-01

    Full Text Available This multicenter case control study investigated, in four countries of America, the proportions of acute myocardial infarction (AMI attributable to cholesterol, smoking, hypertension, body mass index, diabetes and family history of coronary heart disease (attributable risks, AR. AR were estimated using information from 1060 cases of AMI and 1071 controls from Argentina, 323 cases of AMI and 314 controls from Cuba, 200 cases of AMI and 200 controls from Mexico and 266 cases of AMI and 264 controls from Venezuela. AR were obtained from the prevalence of coronary risk factors in the cases and the corresponding Odds Ratio (OR derived through appropriate multivariate models. The AR for AMI observed for hypercholesterolaemia were the following: Venezuela 27%, Mexico 3%, Cuba 30% and Argentina 36%; for diabetes: Venezuela 10%, Mexico 15%, Cuba 5% and Argentina 7% and for body mass index: Venezuela 12%, Mexico 3%, Cuba 19% and Argentina 17%. The same risk factor may have a different attributable risk in different populations. Together, hypercholesterolaemia, hypertension, smoking, diabetes, body mass index and family history of coronary heart disease accounted for 76% of all cases of AMI in Venezuela, 70% in Mexico, 81% in Cuba and 79% in Argentina. The knowledge of attributable risks could have important implications for public health strategies, especially in those countries with limited health care resources.Este estudio caso-control y multicéntrico, investigó en cuatro países de América, la proporción de casos de infarto agudo de miocardio (IAM atribuidos al colesterol, tabaquismo, hipertensión, índice de masa corporal e historia familiar de enfermedad coronaria (riesgo atribuible, RA. Los RA fueron estimados a partir de la información de 1060 casos de IAM y 1071 controles de Argentina, 323 casos de IAM y 314 controles de Cuba, 200 casos de IAM y 200 controles de México y 266 casos de IAM y 264 controles de Venezuela. Los RA fueron

  7. Nutrition.

    Science.gov (United States)

    Durnin, J V

    1976-07-01

    Nutrition appeared somewhat late on the scene in the I.B.P. projects in the U.K., but eventually it occupied an integral part of many of the H.A. (human adaptability) investigations. The nutritional data obtained in the studies of isolated and nearisolated communities in Tristan da Cunha and in New Guinea provided information of wide nutritional significance. There were also detailed and extensive studies in Israel which, similarly to those in New Guinea, attempted to relate nutritional factors to enviroment, working conditions, and physical fitness. Some extraordinarily low energy intakes found in Ethiopians have induced much speculation on the extent which man can adequately adapt to restricted food supplies. Interesting nutritional observations, of general importance, have also arisen from results obtained on such disparate groups as Glasgow adolescents, Tanzanian and Sudanese students, children in Malawi and vegans in the U.K.

  8. Cigarette brand loyalty in Australia: findings from the ITC Four Country Survey.

    Science.gov (United States)

    Cowie, Genevieve A; Swift, Elena; Borland, Ron; Chaloupka, Frank J; Fong, Geoffrey T

    2014-03-01

    There is little academic research on tobacco brand loyalty and switching, and even less in restrictive marketing environments such as Australia. This paper examines tobacco brand family loyalty, reasons for choice of brand and the relation between these and sociodemographic variables over a period of 10 years in Australia. Data from current Australian smokers from 9 waves of the International Tobacco Control Policy Evaluation 4-Country Survey covering the period from 2002 to early 2012. Key measures reported were having a regular brand, use for at least 1 year, brand stability (derived from same reported brand at successive waves), and reasons for choosing brands. Measures of brand loyalty showed little change across the period, with around 80% brand stability and 95% reporting a regular brand. Older adults were more brand-loyal than those under 25. Young people's brand choice was influenced more by friends, whereas older adults were more concerned about health. Price was the most reported reason for brand switching. Those in the higher income tertiles showed more loyalty than those in the lowest. The least addicted smokers also showed less brand loyalty. We found no clear relationship between brand loyalty and policies that were implemented to affect tobacco use. Levels of brand loyalty in Australia are quite high and consistent, and do not appear to have been influenced greatly by changes in tobacco control policies.

  9. Evaluation of regional project to strengthen national health research systems in four countries in West Africa: lessons learned.

    Science.gov (United States)

    Sombié, Issiaka; Aidam, Jude; Montorzi, Gabriela

    2017-07-12

    Since the Commission on Health Research for Development (COHRED) published its flagship report, more attention has been focused on strengthening national health research systems (NHRS). This paper evaluates the contribution of a regional project that used a participatory approach to strengthen NHRS in four post-conflict West African countries - Guinea-Bissau, Liberia, Sierra Leone and Mali. The data from the situation analysis conducted at the start of the project was compared to data from the project's final evaluation, using a hybrid conceptual framework built around four key areas identified through the analysis of existing frameworks. The four areas are governance and management, capacities, funding, and dissemination/use of research findings. The project helped improve the countries' governance and management mechanisms without strengthening the entire NHRS. In the four countries, at least one policy, plan or research agenda was developed. One country put in place a national health research ethics committee, while all four countries could adopt a research information management system. The participatory approach and support from the West African Health Organisation and COHRED were all determining factors. The lessons learned from this project show that the fragile context of these countries requires long-term engagement and that support from a regional institution is needed to address existing challenges and successfully strengthen the entire NHRS.

  10. 关于施甸县城乡学龄前儿童10年生长发育及营养状况分析%Growth and development and nutritional status of preschool children in urban and rural Shidian County:a 10-year retrospective analysis

    Institute of Scientific and Technical Information of China (English)

    赵英

    2014-01-01

    目的:分析施甸县城乡学龄前儿童10年生长发育及营养状况,为改善学龄前儿童营养状况,促进其生长发育提供科学依据。方法采用分层二阶段整群抽样法,抽取施甸县城乡2003年6月-2012年6月5所幼儿园的1050名学龄前儿童的健康检查资料,对其生长发育及营养状况进行回顾性分析。结果2003年-2012年,本县学龄前儿童的生长发育水平呈上升趋势,营养状况得到明显改善。结论近10年,本县学龄前儿童在生长发育及营养状况上得到明显的改善,为保证学龄前儿童的生长发育与营养状况,应加大对健康饮食知识与平衡膳食的宣传与普及,改善儿童的营养供给,预防儿童肥胖,促进其健康成长。%Objective To analyze the growth and development and nutritional status of preschool children in urban and rural Shidian County from 2003 to 2012 and to provide a scientific basis for improving the nutritional status and promoting the growth and development of preschool children. Methods Stratified two-stage cluster sampling was used to collect the physical examination data of 1050 preschool children from 5 kindergartens in urban and rural Shidian County from June 2003 to June 2012 to retrospectively analyze the growth and development and nutritional status of these children. Results From 2003 to 2012, the growth and development of preschool children in Shidian County showed an improving trend, and their nutritional status was greatly improved. Conclusion From 2003 to 2012, preschool children in Shidian County showed significant improvements in growth and development and nutritional status. With the purpose of ensuring the growth and development and nutritional status of preschool children, the spread and popularization of healthy diet knowledge and balanced diet should be strengthened to improve the nutrition supply, prevent obesity, and promote growth.

  11. Growth and development and nutritional status of preschool children in urban and rural Shidian County:a 10-year retrospective analysis%关于施甸县城乡学龄前儿童10年生长发育及营养状况分析

    Institute of Scientific and Technical Information of China (English)

    赵英

    2014-01-01

    目的:分析施甸县城乡学龄前儿童10年生长发育及营养状况,为改善学龄前儿童营养状况,促进其生长发育提供科学依据。方法采用分层二阶段整群抽样法,抽取施甸县城乡2003年6月-2012年6月5所幼儿园的1050名学龄前儿童的健康检查资料,对其生长发育及营养状况进行回顾性分析。结果2003年-2012年,本县学龄前儿童的生长发育水平呈上升趋势,营养状况得到明显改善。结论近10年,本县学龄前儿童在生长发育及营养状况上得到明显的改善,为保证学龄前儿童的生长发育与营养状况,应加大对健康饮食知识与平衡膳食的宣传与普及,改善儿童的营养供给,预防儿童肥胖,促进其健康成长。%Objective To analyze the growth and development and nutritional status of preschool children in urban and rural Shidian County from 2003 to 2012 and to provide a scientific basis for improving the nutritional status and promoting the growth and development of preschool children. Methods Stratified two-stage cluster sampling was used to collect the physical examination data of 1050 preschool children from 5 kindergartens in urban and rural Shidian County from June 2003 to June 2012 to retrospectively analyze the growth and development and nutritional status of these children. Results From 2003 to 2012, the growth and development of preschool children in Shidian County showed an improving trend, and their nutritional status was greatly improved. Conclusion From 2003 to 2012, preschool children in Shidian County showed significant improvements in growth and development and nutritional status. With the purpose of ensuring the growth and development and nutritional status of preschool children, the spread and popularization of healthy diet knowledge and balanced diet should be strengthened to improve the nutrition supply, prevent obesity, and promote growth.

  12. The effects of 10 years Railway investment in Denmark

    DEFF Research Database (Denmark)

    Hansen, Sten A.

    1998-01-01

    The paper retrives the impacts of the last 10 years of investment in railway infrastructure in Denmark and ooncludes, that traveltimes and frequency is large unchanged during that period.......The paper retrives the impacts of the last 10 years of investment in railway infrastructure in Denmark and ooncludes, that traveltimes and frequency is large unchanged during that period....

  13. Cross-cultural aspects of ICT use by older people: preliminary results of a four-country ethnographical study

    DEFF Research Database (Denmark)

    Blat, Josep; Sayago, Sergio; Kälviäinen, Mirja

    2011-01-01

    Culture is crucial in understanding how people use technologies and designing better ones. However, very little is known about cross-cultural aspects of Information and Communication Technologies (ICT) use by older people (60+), despite the heterogeneity of this user group. This short paper...... addresses this issue by drawing on an ethnographical study of ICT use conducted with over 120 people, aged 67-71, in four European countries: Finland, Denmark, Italy and Spain, over a 6-month period. The preliminary results show that making a social, independent and worth use of ICT are common aspects...... across the four countries, despite the so-called heterogeneity of older people as ICT users. This short paper also touches on two key aspects which emerged from the study, engaging older people in research and the evolution of some barriers to technology use....

  14. The Health and Well-Being of Older Adults with Dual Sensory Impairment (DSI in Four Countries.

    Directory of Open Access Journals (Sweden)

    Dawn M Guthrie

    Full Text Available Dual sensory impairment (DSI is a combination of vision and hearing impairments that represents a unique disability affecting all aspects of a person's life. The rates of DSI are expected to increase due to population aging, yet little is known about DSI among older adults (65+. The prevalence of DSI and client characteristics were examined among two groups, namely, older adults receiving home care services or those residing in a long-term care (LTC facility in four countries (Canada, US, Finland, Belgium.Existing data, using an interRAI assessment, were analyzed to compare older adults with DSI to all others across demographic characteristics, functional and psychosocial outcomes.In home care, the prevalence of DSI across the four countries ranged from 13.4% to 24.6%; in LTC facilities, it ranged from 9.7% to 33.9%. Clients with DSI were more likely to be 85+, have moderate/severe cognitive impairment, impairments in activities of daily living, and have communication difficulties. Among residents of LTC facilities, individuals with DSI were more likely to be 85+ and more likely have a diagnosis of Alzheimer's disease. Having DSI increased the likelihood of depression in both care settings, but after adjusting for other factors, it remained significant only in the home care sample.While the prevalence of DSI cross nationally is similar to that of other illnesses such as diabetes, depression, and Alzheimer's disease, we have a limited understanding of its affects among older adults. Raising awareness of this unique disability is imperative to insure that individuals receive the necessary rehabilitation and supportive services to improve their level of independence and quality of life.

  15. Pathologic diagnoses of appendectomy specimens: a 10-year review.

    African Journals Online (AJOL)

    Pathologic diagnoses of appendectomy specimens: a 10-year review. ... Annals of Biomedical Sciences ... Materials and methods: Records of resected appendices with a clinical diagnosis of acute appendicitis submitted to histopathology ...

  16. Implementing services for Early Infant Diagnosis (EID of HIV: a comparative descriptive analysis of national programs in four countries

    Directory of Open Access Journals (Sweden)

    Wade Abdoulaye

    2011-07-01

    Full Text Available Abstract Background There is a significant increase in survival for HIV-infected children who have early access to diagnosis and treatment. The goal of this multi-country review was to examine when and where HIV-exposed infants and children are being diagnosed, and whether the EID service is being maximally utilized to improve health outcomes for HIV-exposed children. Methods In four countries across Africa and Asia existing documents and data were reviewed and key informant interviews were conducted. EID testing data was gathered from the central testing laboratories and was then complemented by health facility level data extraction which took place using a standardized and validated questionnaire Results In the four countries reviewed from 2006 to 2009 EID sample volumes rose dramatically to an average of >100 samples per quarter in Cambodia and Senegal, >7,000 samples per quarter in Uganda, and >2,000 samples per quarter in Namibia. Geographic coverage of sites also rapidly expanded to 525 sites in Uganda, 205 in Namibia, 48 in Senegal, and 26 in Cambodia in 2009. However, only a small proportion of testing was done at lower-level health facilities: in Uganda Health Center IIs and IIIs comprised 47% of the EID collection sites, but only 11% of the total tests, and in Namibia 15% of EID sites collected >93% of all samples. In all countries except for Namibia, more than 50% of the EID testing was done after 2 months of age. Few sites had robust referral mechanisms between EID and ART. In a sub-sample of children, we noted significant attrition of infants along the continuum of care post testing. Only 22% (Senegal, 37% (Uganda, and 38% (Cambodia of infants testing positive by PCR were subsequently initiated onto treatment. In Namibia, which had almost universal EID coverage, more than 70% of PCR-positive infants initiated ART in 2008. Conclusions While EID testing has expanded dramatically, a large proportion of PCR- positive infants are

  17. Trends in Roll-Your-Own Smoking: Findings from the ITC Four-Country Survey (2002–2008

    Directory of Open Access Journals (Sweden)

    David Young

    2012-01-01

    Methods. Participants were 19,456 cigarette smokers interviewed during the longitudinal International Tobacco Control (ITC Four-Country Survey in Canada, USA, UK, and Australia. Results. “Predominant” RYO use (i.e., >50% of cigarettes smoked increased significantly in the UK and USA as a proportion of all cigarette use (both P<.001 and in all countries as a proportion of any RYO use (all P<.010. Younger, financially stressed smokers are disproportionately contributing to “some” use (i.e., ≤50% of cigarettes smoked. Relative cost was the major reason given for using RYO, and predominant RYO use is consistently and significantly associated with low income. Conclusions. RYO market trends reflect the price advantages accruing to RYO (a product of favourable taxation regimes in some jurisdictions reinforced by the enhanced control over the amount of tobacco used, especially following the impact of the Global Financial Crisis; the availability of competing low-cost alternatives to RYO; accessibility of duty-free RYO tobacco; and tobacco industry niche marketing strategies. If policy makers want to ensure that the RYO option does not inhibit the fight to end the tobacco epidemic, especially amongst the disadvantaged, they need to reduce the price advantage, target additional health messages at (young RYO users, and challenge niche marketing of RYO by the industry.

  18. How do price minimizing behaviors impact smoking cessation? Findings from the International Tobacco Control (ITC) Four Country Survey.

    Science.gov (United States)

    Licht, Andrea S; Hyland, Andrew J; O'Connor, Richard J; Chaloupka, Frank J; Borland, Ron; Fong, Geoffrey T; Nargis, Nigar; Cummings, K Michael

    2011-05-01

    This paper examines how price minimizing behaviors impact efforts to stop smoking. Data on 4,988 participants from the International Tobacco Control Policy Evaluation (ITC) Four-Country Survey who were smokers at baseline (wave 5) and interviewed at a 1 year follow-up were used. We examined whether price minimizing behaviors at baseline predicted: (1) cessation, (2) quit attempts, and (3) successful quit attempts at one year follow up using multivariate logistic regression modeling. A subset analysis included 3,387 participants who were current smokers at waves 5 and 6 and were followed through wave 7 to explore effects of changing purchase patterns on cessation. Statistical tests for interaction were performed to examine the joint effect of SES and price/tax avoidance behaviors on cessation outcomes. Smokers who engaged in any price/tax avoidance behaviors were 28% less likely to report cessation. Persons using low/untaxed sources were less likely to quit at follow up, those purchasing cartons were less likely to make quit attempts and quit, and those using discount cigarettes were less likely to succeed, conditional on making attempts. Respondents who utilized multiple behaviors simultaneously were less likely to make quit attempts and to succeed. SES did not modify the effects of price minimizing behaviors on cessation outcomes. The data from this paper indicate that the availability of lower priced cigarette alternatives may attenuate public health efforts aimed at to reduce reducing smoking prevalence through price and tax increases among all SES groups.

  19. Spousal similarity in coping and depressive symptoms over 10 years.

    Science.gov (United States)

    Holahan, Charles J; Moos, Rudolf H; Moerkbak, Marie L; Cronkite, Ruth C; Holahan, Carole K; Kenney, Brent A

    2007-12-01

    Following a baseline sample of 184 married couples over 10 years, the present study develops a broadened conceptualization of linkages in spouses' functioning by examining similarity in coping as well as in depressive symptoms. Consistent with hypotheses, results demonstrated (a) similarity in depressive symptoms within couples across 10 years, (b) similarity in coping within couples over 10 years, and (c) the role of coping similarity in strengthening depressive similarity between spouses. Spousal similarity in coping was evident for a composite measure of percent approach coping as well as for component measures of approach and avoidance coping. The role of coping similarity in strengthening depressive symptom similarity was observed for percent approach coping and for avoidance coping. These findings support social contextual models of psychological adjustment that emphasize the importance of dynamic interdependencies between individuals in close relationships.

  20. Actual 10-year survivors following resection of adrenocortical carcinoma.

    Science.gov (United States)

    Tran, Thuy B; Postlewait, Lauren M; Maithel, Shishir K; Prescott, Jason D; Wang, Tracy S; Glenn, Jason; Phay, John E; Keplinger, Kara; Fields, Ryan C; Jin, Linda X; Weber, Sharon M; Salem, Ahmed; Sicklick, Jason K; Gad, Shady; Yopp, Adam C; Mansour, John C; Duh, Quan-Yang; Seiser, Natalie; Solorzano, Carmen C; Kiernan, Colleen M; Votanopoulos, Konstantinos I; Levine, Edward A; Hatzaras, Ioannis; Shenoy, Rivfka; Pawlik, Timothy M; Norton, Jeffrey A; Poultsides, George A

    2016-12-01

    Adrenocortical carcinoma (ACC) is a rare and aggressive malignancy with limited therapeutic options beyond surgical resection. The characteristics of actual long-term survivors following surgical resection for ACC have not been previously reported. Patients who underwent resection for ACC at one of 13 academic institutions participating in the US Adrenocortical Carcinoma Group from 1993 to 2014 were analyzed. Patients were stratified into four groups: early mortality (died within 2 years), late mortality (died within 2-5 years), actual 5-year survivor (survived at least 5 years), and actual 10-year survivor (survived at least 10 years). Patients with less than 5 years of follow-up were excluded. Among the 180 patients available for analysis, there were 49 actual 5-year survivors (27%) and 12 actual 10-year survivors (7%). Patients who experienced early mortality had higher rates of cortisol-secreting tumors, nodal metastasis, synchronous distant metastasis, and R1 or R2 resections (all P year survivors. Ten of twelve actual 10-year survivors were women, and of the seven 10-year survivors who experienced disease recurrence, five had undergone repeat surgery to resect the recurrence. Surgery for ACC can offer a 1 in 4 chance of actual 5-year survival and a 1 in 15 chance of actual 10-year survival. Long-term survival was often achieved with repeat resection for local or distant recurrence, further underscoring the important role of surgery in managing patients with ACC. J. Surg. Oncol. 2016;114:971-976. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  1. Expected innovations of optical lithography in the next 10 years

    Science.gov (United States)

    Owa, Soichi; Hirayanagi, Noriyuki

    2016-03-01

    In the past 10 years, immersion lithography has been the most effective high volume manufacturing method for the critical layers of semiconductor devices. Thinking of the next 10 years, we can expect continuous improvement on existing 300 mm wafer scanners with better accuracy and throughput to enhance the total output value per input cost. This value productivity, however, can be upgraded also by larger innovations which might happen in optical lithography. In this paper, we will discuss the possibilities and the impossibilities of potential innovation ideas of optical lithography, which are 450 mm wafer, optical maskless, multicolor lithography, and metamaterial.

  2. Looking forward, looking back-10 years in urology.

    Science.gov (United States)

    Albersen, Maarten; Cartwright, Rufus; Choyke, Peter; Goldenberg, S Larry; Goldman, Howard; Lawrentschuk, Nathan; Linehan, W Marston; Murphy, Declan; Nagler, Harris; Scardino, Peter; Shortliffe, Linda; Stenzl, Arnulf; Theodorescu, Dan

    2014-11-01

    When Nature Reviews Urology launched in 2004, the field of urology was vastly different to that which we work in today, and the past 10 years have seen the field change immensely. As a specialty on the forefront of cutting-edge innovation, urologists are often the first to embrace new technologies and ideas. In this Viewpoint, members of the Nature Reviews Urology advisory board were asked what they thought was the most important change, issue or innovation in urology in the past 10 years, and what they expected to be the most important in the next decade. Here are their opinions.

  3. Peritoneal dialysis in an ageing population: a 10-year experience.

    LENUS (Irish Health Repository)

    Smyth, Andrew

    2012-02-01

    Chronic kidney disease (CKD) is becoming increasingly prevalent and there are increasing numbers of older patients with advanced CKD. Peritoneal dialysis (PD) is a potential treatment. This study aims to compare PD outcomes in age-defined populations in the largest PD centre in the Republic of Ireland over 10 years.

  4. 10 Years of Media Literacy Education in K-12 Schools

    Science.gov (United States)

    Daunic, Rhys

    2011-01-01

    When the author started working with teachers and students on classroom multimedia productions a little over 10 years ago, he had not yet encountered the term "media literacy", nor did he realize he had joined a long standing international movement of media literacy educators. Serendipitous exposure to "old-media" texts by Neil Postman and Noam…

  5. After Cotton Prices Hit a 10-Year Peak...

    Institute of Scientific and Technical Information of China (English)

    Wang Zhaofeng

    2010-01-01

    @@ "With the fifth-grade seed cotton being priced at 4.5 yuan per 500 grams and Xinjiang lint cotton at nearly RMB 20,000 per ton, cotton prices have rocketed to a 10-year peak," Gap Chaoshan, President of the Liaocheng Cotton Association, told the reporter on September 26.

  6. Duodenal adenocarcinoma in a 10-year-old boy

    Directory of Open Access Journals (Sweden)

    Zouari Mohamed

    2014-01-01

    Full Text Available Gastrointestinal malignancies are extremely rare in the paediatric population and duodenal cancers represent an even more unusual entity. It represents 0.3-1% of all gastrointestinal tumours. A case report of a 10-year-old boy with duodenal adenocarcinoma is reported and the difficulties of diagnosing and treating this rare tumour are discussed.

  7. Neuropsychological aspects of 10-year-old children.

    Science.gov (United States)

    Osborn, Ellen; Pereira, Liliane Desgualdo

    2012-01-01

    To characterize neuropsychological aspects of 10-year-old children. Out of 30 children, 26 cognitively normal 10-year-old public school students answered tests extracted from Luria-Nebraska Neuropsychological Battery: Children's Revision. The study was transversal. Descriptive and inferential statistical analysis were carried out. Most of the 10-year-old children retold a story (69.2%), understood it making correct inference (84.6%) and reproduced it adequately in writing (76.9%)--14.9% was the average number of incorrectly written words and 0.179 was the errors per written word coefficient. Besides, 53.8% showed logical thought process and 73.1% had a correct notion of "x more than...". They got five out of eight in the visuo-spatial test, an intermediary result. These results show that the tertiary areas of units II and III are developed in most 10-year-old children. The most frequent types of written mistakes were: oral influence (26.3%), multiple representation (22.5%) and omission (18.4%). As to coding principles, the mostly uncomplied with rule was vowel nasalization at end of syllable (23,53%). Ten-year-old children in the studied population understood and reproduced a story orally and in writing with a low coefficient error/word. The majority completed the visuospatial tests and presented logical thought process. When "x more than..." notion is absent it may be an indicator that all is not well in the reading/writing process.

  8. Duodenal adenocarcinoma in a 10-year-old boy.

    Science.gov (United States)

    Mohamed, Zouari; Habib, Bouthour; Rabia, Ben Abdallah; Youssef, Hlel; Riath, Ben Malek; Youssef, Gharbi; Nejib, Kaabar

    2014-01-01

    Gastrointestinal malignancies are extremely rare in the paediatric population and duodenal cancers represent an even more unusual entity. It represents 0.3-1% of all gastrointestinal tumours. A case report of a 10-year-old boy with duodenal adenocarcinoma is reported and the difficulties of diagnosing and treating this rare tumour are discussed.

  9. Rate and determinants of 10-year persistence with antihypertensive drugs

    NARCIS (Netherlands)

    Van Wijk, Boris Lg; Klungel, Olaf H; Heerdink, Eibert R; de Boer, Anthonius

    2005-01-01

    OBJECTIVE: To assess the proportion of patients starting with antihypertensive drug treatment who continued treatment for at least 10 years. DESIGN: A retrospective cohort study. SETTING: The PHARMO record linkage system containing drug dispensing records from community pharmacies and linked hospita

  10. Career Theory Building in AJCD during Its Inaugural 10 Years.

    Science.gov (United States)

    Prideaux, Lee-Ann; Creed, Peter

    2002-01-01

    A review of the first 10 years of the Australian Journal of Career Development identified 26 articles meeting methodological criteria. These topics predominated: cross-sectional analyses, Holland's theory of vocational choice, self-efficacy/self-concept theory, gender issues, and career counseling/career education. A need for an…

  11. How Do Price Minimizing Behaviors Impact Smoking Cessation? Findings from the International Tobacco Control (ITC Four Country Survey

    Directory of Open Access Journals (Sweden)

    Nigar Nargis

    2011-05-01

    Full Text Available This paper examines how price minimizing behaviors impact efforts to stop smoking. Data on 4,988 participants from the International Tobacco Control Policy Evaluation (ITC Four-Country Survey who were smokers at baseline (wave 5 and interviewed at a 1 year follow-up were used. We examined whether price minimizing behaviors at baseline predicted: (1 cessation, (2 quit attempts, and (3 successful quit attempts at one year follow up using multivariate logistic regression modeling. A subset analysis included 3,387 participants who were current smokers at waves 5 and 6 and were followed through wave 7 to explore effects of changing purchase patterns on cessation. Statistical tests for interaction were performed to examine the joint effect of SES and price/tax avoidance behaviors on cessation outcomes. Smokers who engaged in any price/tax avoidance behaviors were 28% less likely to report cessation. Persons using low/untaxed sources were less likely to quit at follow up, those purchasing cartons were less likely to make quit attempts and quit, and those using discount cigarettes were less likely to succeed, conditional on making attempts. Respondents who utilized multiple behaviors simultaneously were less likely to make quit attempts and to succeed. SES did not modify the effects of price minimizing behaviors on cessation outcomes. The data from this paper indicate that the availability of lower priced cigarette alternatives may attenuate public health efforts aimed at to reduce reducing smoking prevalence through price and tax increases among all SES groups. This paper examines how price minimizing behaviors impact efforts to stop smoking. Data on 4,988 participants from the International Tobacco Control Policy Evaluation (ITC Four-Country Survey who were smokers at baseline (wave 5 and interviewed at a 1 year follow-up were used. We examined whether price minimizing behaviors at baseline predicted: (1 cessation, (2 quit attempts, and (3 successful

  12. Australian smokers' support for plain or standardised packs before and after implementation: findings from the ITC Four Country Survey.

    Science.gov (United States)

    Swift, Elena; Borland, Ron; Cummings, K Michael; Fong, Geoffrey T; McNeill, Ann; Hammond, David; Thrasher, James F; Partos, Timea R; Yong, Hua-Hie

    2015-11-01

    Plain packaging (PP) for tobacco products was fully implemented in Australia on 1 December 2012 along with larger graphic health warnings. Using longitudinal data from the Australian arm of the ITC Four Country Survey, we examined attitudes to the new packs before and after implementation, predictors of attitudinal change, and the relationship between support and quitting activity. A population-based cohort study design, with some cross-sectional analyses. Surveys of Australian smokers assessed attitudes to PP at four time points prior to implementation (from 2007 to 2012) and one post-implementation wave collected (early/mid-2013). Trend analysis showed a slight rise in opposition to PP among smokers in the waves leading up to their implementation, but no change in support. Support for PP increased significantly after implementation (28.2% pre vs 49% post), such that post-PP more smokers were supportive than opposed (49% vs 34.7%). Multivariate analysis showed support either before or after implementation was predicted by belief in greater adverse health impacts of smoking, desire to quit and lower addiction. Among those not supportive before implementation, having no clear opinion about PP (versus being opposed) prior to the changes also predicted support post-implementation. Support for PP was prospectively associated with higher levels of quitting activity. Since implementation of PP along with larger warnings, support among Australian smokers has increased. Support is related to lower addiction, stronger beliefs in the negative health impacts of smoking, and higher levels of quitting activity. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  13. Harmonization of community health worker programs for HIV: A four-country qualitative study in Southern Africa.

    Directory of Open Access Journals (Sweden)

    Jan-Walter De Neve

    2017-08-01

    Full Text Available Community health worker (CHW programs are believed to be poorly coordinated, poorly integrated into national health systems, and lacking long-term support. Duplication of services, fragmentation, and resource limitations may have impeded the potential impact of CHWs for achieving HIV goals. This study assesses mediators of a more harmonized approach to implementing large-scale CHW programs for HIV in the context of complex health systems and multiple donors.We undertook four country case studies in Lesotho, Mozambique, South Africa, and Swaziland between August 2015 and May 2016. We conducted 60 semistructured interviews with donors, government officials, and expert observers involved in CHW programs delivering HIV services. Interviews were triangulated with published literature, country reports, national health plans, and policies. Data were analyzed based on 3 priority areas of harmonization (coordination, integration, and sustainability and 5 components of a conceptual framework (the health issue, intervention, stakeholders, health system, and context to assess facilitators and barriers to harmonization of CHW programs. CHWs supporting HIV programs were found to be highly fragmented and poorly integrated into national health systems. Stakeholders generally supported increasing harmonization, although they recognized several challenges and disadvantages to harmonization. Key facilitators to harmonization included (i a large existing national CHW program and recognition of nongovernmental CHW programs, (ii use of common incentives and training processes for CHWs, (iii existence of an organizational structure dedicated to community health initiatives, and (iv involvement of community leaders in decision-making. Key barriers included a wide range of stakeholders and lack of ownership and accountability of non-governmental CHW programs. Limitations of our study include subjectively selected case studies, our focus on decision-makers, and limited

  14. The relative roles of ANC and EPI in the continuous distribution of LLINs: a qualitative study in four countries.

    Science.gov (United States)

    Theiss-Nyland, Katherine; Koné, Diakalia; Karema, Corine; Ejersa, Waqo; Webster, Jayne; Lines, Jo

    2017-05-01

    The continuous distribution of long-lasting insecticidal nets (LLINs) for malaria prevention, through the antenatal care (ANC) and the Expanded Programme on Immunizations (EPI), is recommended by the WHO to improve and maintain LLIN coverage. Despite these recommendations, little is known about the relative strengths and weaknesses of the ANC and EPI-based LLIN distribution. This study aimed to explore and compare the roles of the ANC and EPI for LLIN distribution in four African countries. In a qualitative evaluation of continuous distribution through the ANC and EPI, semi-structured, individual and group interviews were conducted in Kenya, Malawi, Mali, and Rwanda. Respondents included national, sub-national, and facility-level health staff, and were selected to capture a range of roles related to malaria, ANC and EPI programmes. Policies, guidelines, and data collection tools were reviewed as a means of triangulation to assess the structure of LLIN distribution, and the methods of data collection and reporting for malaria, ANC and EPI programmes. In the four countries visited, distribution of LLINs was more effectively integrated through ANC than through EPI because of a) stronger linkages and involvement between malaria and reproductive health programmes, as compared to malaria and EPI, and b) more complete programme monitoring for ANC-based distribution, compared to EPI-based distribution. Opportunities for improving the distribution of LLINs through these channels exist, especially in the case of EPI. For both ANC and EPI, integrated distribution of LLINs has the potential to act as an incentive, improving the already strong coverage of both these essential services. The collection and reporting of data on LLINs distributed through the ANC and EPI can provide insight into the performance of LLIN distribution within these programmes. Greater attention to data collection and use, by both the global malaria community, and the integrated programmes, can improve

  15. Helping a 10-year-old Haitian girl with vaginitis.

    Science.gov (United States)

    Leveille-Tulce, Anne Marie B

    2014-06-01

    The purpose of this case study is to demonstrate how nurses who work with Haitian children and families can use NANDA-I (diagnosis), the Nursing Outcomes Classification, and the Nursing Interventions Classification to assist a 10-year-old child with symptoms of vaginitis. The case study derives from the author's experience and literature sources. This case study demonstrates a nurse's clinical decision making while providing care to a 10-year-old girl with symptoms of vaginitis. Increased knowledge and awareness about appropriate health behaviors can increase patients' power and enable them to freely act and adopt health behaviors to improve health outcomes. Placing patients at the center of the nursing process and partnering with patients to plan and develop interventions enable them to take actions and improve health outcomes. © 2013 NANDA International.

  16. Optogenetics: 10 years of microbial opsins in neuroscience.

    Science.gov (United States)

    Deisseroth, Karl

    2015-09-01

    Over the past 10 years, the development and convergence of microbial opsin engineering, modular genetic methods for cell-type targeting and optical strategies for guiding light through tissue have enabled versatile optical control of defined cells in living systems, defining modern optogenetics. Despite widespread recognition of the importance of spatiotemporally precise causal control over cellular signaling, for nearly the first half (2005-2009) of this 10-year period, as optogenetics was being created, there were difficulties in implementation, few publications and limited biological findings. In contrast, the ensuing years have witnessed a substantial acceleration in the application domain, with the publication of thousands of discoveries and insights into the function of nervous systems and beyond. This Historical Commentary reflects on the scientific landscape of this decade-long transition.

  17. Atypical presentation of macrophagic myofasciitis 10 years post vaccination.

    LENUS (Irish Health Repository)

    Ryan, Aisling M

    2012-02-03

    Macrophagic myofasciitis (MMF) is an uncommon inflammatory disorder of muscle believed to be due to persistence of vaccine-derived aluminium hydroxide at the site of injection. The condition is characterised by diffuse myalgias, arthralgia and fatigue. We describe a patient with histologically confirmed MMF whose presentation was atypical with left chest and upper limb pain beginning more than 10 years post vaccination. Treatment with steroids led to symptomatic improvement. Although rare, clinicians should consider MMF in cases of atypical myalgia.

  18. Atypical presentation of macrophagic myofasciitis 10 years post vaccination.

    Science.gov (United States)

    Ryan, Aisling M; Bermingham, Niamh; Harrington, Hugh J; Keohane, Catherine

    2006-12-01

    Macrophagic myofasciitis (MMF) is an uncommon inflammatory disorder of muscle believed to be due to persistence of vaccine-derived aluminium hydroxide at the site of injection. The condition is characterised by diffuse myalgias, arthralgia and fatigue. We describe a patient with histologically confirmed MMF whose presentation was atypical with left chest and upper limb pain beginning more than 10 years post vaccination. Treatment with steroids led to symptomatic improvement. Although rare, clinicians should consider MMF in cases of atypical myalgia.

  19. [Percutaneous transluminal angioplasty (PTA), 10 years of experience].

    Science.gov (United States)

    Estevan Solano, J M; García-Cosío, J; Rodríguez, E; Barreiro, A; Maynar, M

    1991-01-01

    Authors present their experiences during 10 years (1980-89) with the treatment of peripheral arteriopathies with the ATP. Between a total of 455 procedures, an accumulative permeability of 82% in the iliac sector and 71% in the femoro-popliteal sector in elective indications was reached. The total availability of this therapeutic method, the accurate selection of indications and the valious cooperation between Angioradiology and Vascular Surgery Departments should be noted.

  20. Fractures of the mandible and maxilla: A 10-year analysis

    OpenAIRE

    2016-01-01

    Background Previous analysis of jaw fracture hospitalisations in Western Australia (WA) indicated disproportionately high rates of hospitalisations for Aboriginal people. This study was to follow-up on the earlier analysis to determine if inequalities in terms of jaw fracture hospitalisation rates between Aboriginal and non-Aboriginal people have changed. Aims This study, done over a 10-year period from 1999/2000 to 2008/2009, aimed to determine rates of hospitalisations for jaw f...

  1. Avian response to bottomland hardwood reforestation: the first 10 years

    Science.gov (United States)

    Twedt, D.J.; Wilson, R.R.; Henne-Kerr, J.L.; Grosshuesch, D.A.

    2002-01-01

    Bttomland hardwood forests were planted on agricultural fields in Mississippi and Louisiana using either predominantly Quercus species (oaks) or Populus deltoides (eastern cottonwood). We assessed avian colonization of these reforested sites between 2 and 10 years after planting. Rapid vertical growth of cottonwoods (circa 2 - 3 m / yr) resulted in sites with forest structure that supported greater species richness of breeding birds, increased Shannon diversity indices, and supported greater territory densities than on sites planted with slower-growing oak species. Grassland birds (Spiza americana [Dickcissel], and Sturnella magna [Eastern Meadowlark]) were indicative of species breeding on oak-dominated reforestation # 10 years old. Agelaius phoeniceus (Red-winged Blackbird) and Colinus virginianus (Northern Bobwhite) characterized cottonwood reforestation # 4 years old, whereas 14 species of shrub-scrub birds (e.g., Passerina cyanea [Indigo Bunting]) and early-successional forest birds (e.g., Vireo gilvus [Warbling Vireo]) typified cottonwood reforestation 5 to 9 years after planting. Rates of daily nest survival did not differ between reforestation strategies. Nest parasitism increased markedly in older cottonwood stands, but was overwhelmed by predation as a cause of nest failure. Based on Partners in Flight prioritization scores and territory densities, the value of cottonwood reforestation for avian conservation was significantly greater than that of oak reforestation during their first 10 years. Because of benefits conferred on breeding birds, we recommend reforestation of bottomland hardwoods include a high proportion of fast-growing, early successional species such as cottonwood.

  2. Perceived Partner Responsiveness Predicts Diurnal Cortisol Profiles 10 Years Later

    Science.gov (United States)

    Slatcher, Richard B.; Selcuk, Emre; Ong, Anthony D.

    2015-01-01

    Several decades of research have demonstrated that marital relationships have a powerful influence on physical health. However, surprisingly little is known about how marriage affects health—both in terms of psychological processes and biological ones. We investigated the associations between perceived partner responsiveness—the extent to which people feel understood, cared for and appreciated by their romantic partner—and diurnal cortisol over a 10-year period in a large sample of married and cohabitating couples in the U.S. Partner responsiveness predicted higher wakeup cortisol values and steeper (“healthier”) cortisol slopes at the 10-year follow-up, and these associations remained strong after controlling for demographic factors, depressive symptoms, agreeableness, and other positive and negative relationship factors. Further, declines in negative affect over the 10-year period mediated the prospective association between responsiveness and cortisol slope. These findings suggest that diurnal cortisol may be a key biological pathway through which social relationships impact long-term health. PMID:26015413

  3. Towards a Science of Community Stakeholder Engagement in Biomedical HIV Prevention Trials: An Embedded Four-Country Case Study.

    Science.gov (United States)

    Newman, Peter A; Rubincam, Clara; Slack, Catherine; Essack, Zaynab; Chakrapani, Venkatesan; Chuang, Deng-Min; Tepjan, Suchon; Shunmugam, Murali; Roungprakhon, Surachet; Logie, Carmen; Koen, Jennifer; Lindegger, Graham

    2015-01-01

    Broad international guidelines and studies in the context of individual clinical trials highlight the centrality of community stakeholder engagement in conducting ethically rigorous HIV prevention trials. We explored and identified challenges and facilitators for community stakeholder engagement in biomedical HIV prevention trials in diverse global settings. Our aim was to assess and deepen the empirical foundation for priorities included in the GPP guidelines and to highlight challenges in implementation that may merit further attention in subsequent GPP iterations. From 2008-2012 we conducted an embedded, multiple case study centered in Thailand, India, South Africa and Canada. We conducted in-depth interviews and focus groups with respondents from different trial-related subsystems: civil society organization representatives, community advocates, service providers, clinical trialists/researchers, former trial participants, and key HIV risk populations. Interviews/focus groups were recorded, and coded using thematic content analysis. After intra-case analyses, we conducted cross-case analysis to contrast and synthesize themes and sub-themes across cases. Lastly, we applied the case study findings to explore and assess UNAIDS/AVAC GPP guidelines and the GPP Blueprint for Stakeholder Engagement. Across settings, we identified three cross-cutting themes as essential to community stakeholder engagement: trial literacy, including lexicon challenges and misconceptions that imperil sound communication; mistrust due to historical exploitation; and participatory processes: engaging early; considering the breadth of "community"; and, developing appropriate stakeholder roles. Site-specific challenges arose in resource-limited settings and settings where trials were halted. This multiple case study revealed common themes underlying community stakeholder engagement across four country settings that largely mirror GPP goals and the GPP Blueprint, as well as highlighting

  4. Socio-Economic Variation in Price Minimizing Behaviors: Findings from the International Tobacco Control (ITC Four Country Survey

    Directory of Open Access Journals (Sweden)

    Nigar Nargis

    2011-01-01

    Full Text Available This paper examines how socio-economic status (SES modifies how smokers adjust to changes in the price of tobacco products through utilization of multiple price minimizing techniques. Data come from the International Tobacco Control Policy Evaluation (ITC Four Country Survey, nationally representative samples of adult smokers and includes respondents from Canada, the United States, the United Kingdom and Australia. Cross-sectional analyses were completed among 8,243 respondents (7,038 current smokers from the survey wave conducted between October 2006 and February 2007. Analyses examined predictors of purchasing from low/untaxed sources, using discount cigarettes or roll-your-own (RYO tobacco, purchasing cigarettes in cartons, and engaging in high levels of price and tax avoidance at last purchase. All analyses tested for interactions with SES and were weighted to account for changing and under-represented demographics. Relatively high levels of price and tax avoidance behaviors were present; 8% reported buying from low or untaxed source; 36% used discount or generic brands, 13.5% used RYO tobacco, 29% reported purchasing cartons, and 63% reported using at least one of these high price avoidance behaviors. Respondents categorized as having low SES were approximately 26% less likely to report using low or untaxed sources and 43% less likely to purchase tobacco by the carton. However, respondents with low SES were 85% more likely to report using discount brands/RYO compared to participants with higher SES. Overall, lower SES smokers were 25% more likely to engage in at least one or more tax avoidance behaviors compared to their higher SES counterparts. Price and tax avoidance behaviors are relatively common among smokers of all SES strata, but strategies differed with higher SES groups more likely to report traveling to a low-tax location to avoid paying higher prices, purchase duty free tobacco, and purchase by cartons instead of packs all of

  5. Project Energize: intervention development and 10 years of progress in preventing childhood obesity.

    Science.gov (United States)

    Rush, Elaine; Cairncross, Carolyn; Williams, Margaret Hinepo; Tseng, Marilyn; Coppinger, Tara; McLennan, Steph; Latimer, Kasha

    2016-01-26

    Prevention of childhood obesity is a global priority. The school setting offers access to large numbers of children and the ability to provide supportive environments for quality physical activity and nutrition. This article describes Project Energize, a through-school physical activity and nutrition programme that celebrated its 10-year anniversary in 2015 so that it might serve as a model for similar practices, initiatives and policies elsewhere. The programme was envisaged and financed by the Waikato District Health Board of New Zealand in 2004 and delivered by Sport Waikato to 124 primary schools as a randomised controlled trial from 2005 to 2006. The programme has since expanded to include all 242 primary schools in the Waikato region and 70 schools in other regions, including 53,000 children. Ongoing evaluation and development of Project Energize has shown it to be sustainable (ongoing for >10 years), both effective (lower obesity, higher physical fitness) and cost effective (one health related cost quality adjusted life year between $18,000 and $30,000) and efficient ($45/child/year) as a childhood 'health' programme. The programme's unique community-based approach is inclusive of all children, serving a population that is 42% Māori, the indigenous people of New Zealand. While the original nine healthy eating and seven quality physical activity goals have not changed, the delivery and assessment processes has been refined and the health service adapted over the 10 years of the programme existence, as well as adapted over time to other settings including early childhood education and schools in Cork in Ireland. Evaluation and research associated with the programme delivery and outcomes are ongoing. The dissemination of findings to politicians and collaboration with other service providers are both regarded as priorities.

  6. Chronic pain in multiple sclerosis: A 10-year longitudinal study.

    Science.gov (United States)

    Young, Jamie; Amatya, Bhasker; Galea, Mary P; Khan, Fary

    2017-07-01

    Pain is a common symptom associated with multiple sclerosis (MS), and has lasting effects on an individual's functional capacity and quality of life. A wide range of prevalence rates of pain (between 23% and 90%)have been reported in MS and this is mainly due to the methodological differences amongst the studies such as variability in patient sources, method of sampling and the definition of pain used. Chronic pain in MS, defined as pain lasting for greater than 3-6 months, can have a significant impact on their biopsychosocial health, including negative impact on activities of daily living, relationships and social participation. The long-term course of MS-related pain and its impact in an Australian cohort over a 7-year period has been investigated earlier. The aim of this longitudinal study was to describe the impact of chronic pain, pain-related disability and carer burden in persons with MS over a 10-year period. The aim of this longitudinal study was to describe the impact of chronic pain, pain-related disability and carer burden in persons with MS over a 10-year period. This was a prospective longitudinal study conducted at the Rehabilitation Department of Royal Melbourne Hospital (RMH), a tertiary referral hospital in Victoria and Australia. The source of participants was from the RMH MS database and contains detailed MS patient information including demographic data, diagnosis details (using McDonald's criteria), pain characteristics. Structured face-face interviews and validated measures were used, which include the visual analogue scale (VAS); chronic pain grade (CPG); the assessment of quality of life (AQoL) and the carer strain index (CSI). The mean age of the participants (n=70) was 55.3 years and majority (70%) were female. The mean age of the participants (n=70) was 55.3 years and majority (70%) were female. The findings show that over time (10 years), participants report having greater bilateral bodily pain and greater description of pain as 'worse

  7. A 10 YEAR SURVEY ON CHILDHOOD CNS TUMORS

    Directory of Open Access Journals (Sweden)

    F. Jadali

    2008-06-01

    Full Text Available ObjectiveTumors of the central nervous system constitute the largest group of solid neoplasms in children and are second only to leukemia in their overall frequency during childhood. The main purpose of the present study is to determine the incidence, age, sex, location and histological diagnosis of CNS tumors in children, less than 15 years of age, in the Mofid Children’s Hospital, in the past 10 years.Materials and Methods In this descriptive retrospective study we reviewed the medical records of 143children with diagnosis of CNS tumors admitted during the past 10 years in neurology and surgery departments of Mofid Children’s Hospital between the years 1996 and 2006.ResultsDuring the 10 year study period, CNS tumor was diagnosed in 143 patients; of these tumors, 119 were intracranial and 58 were intraspinal; 51.3% of brain tumors were located in the supratentorial and 48.7% in the infratentorial regions. The most common intracranial neoplasms were astrocytic tumors (36.8%, embryonal tumors (31.1% and ependymal tumors (13.4%. Of the intraspinal neoplasms the most frequently noted were embryonal tumors (37.5%, mesenchymal meningothelial tumors (20.8%, followed by astrocytic tumors (16.7%. The median age at diagnosis was 8.9 ± 4.1 years with a male to female ratio of 1.4:1 (P<0.5. The most common intracranial astrocytic and embryonal neoplasms were pilocytic astrocytoma and medulloblastoma / PNET respectively.ConclusionBrain tumors in children constitute a diverse group in terms of incidence, distribution and histopathological diagnosis.

  8. A 10 YEAR SURVEY ON CHILDHOOD CNS TUMORS

    Directory of Open Access Journals (Sweden)

    F. Jadali

    2008-10-01

    Full Text Available AbstractObjectiveTumors of the central nervous system constitute the largest group of solid neoplasms in children and are second only to leukemia in their overall frequency during childhood. The main purpose of the present study is to determine the incidence, age, sex, location and histological diagnosis of CNS tumors in children, less than 15 years of age, in the Mofid Children's Hospital, in the past 10 years. Materials and MethodsIn this descriptive retrospective study we reviewed the medical records of 143 children with diagnosis of CNS tumors admitted during the past 10 years in neurology and surgery departments of Mofid Children's Hospital between the years 1996 and 2006.ResultsDuring the 10 year study period, CNS tumor was diagnosed in 143 patients; of these tumors, 119 were intracranial and 58 were intraspinal; 51.3% of brain tumors were located in the supratentorial and 48.7% in the infratentorial regions. The most common intracranial neoplasms were astrocytic tumors (36.8%, embryonal tumors (31.1% and ependymal tumors (13.4%. Of the intraspinal neoplasms the most frequently noted were embryonal tumors(37.5%, mesenchymal meningothelial tumors (20.8%, followed by astrocytic tumors (16.7%. The median age at diagnosis was 8.9 ± 4.1 years with a male to female ratio of 1.4:1 (P Conclusion Brain tumors in children constitute a diverse group in terms of incidence,distribution and histopathological diagnosis.Keywords: CNS tumors, Histopathology, Children.

  9. Etiology of stillbirth at term: a 10-year cohort study.

    Science.gov (United States)

    Walsh, Colin A; Vallerie, Amy M; Baxi, Laxmi V

    2008-07-01

    To examine etiological factors contributing to cases of intrauterine fetal demise in term pregnancies over a 10-year period. This was a retrospective cohort analysis of 29 908 term (37(+0) to 41(+6) weeks gestation) infants delivering in a single tertiary-referral university institution over the 10-year period from 1996 to 2005. Cases of stillbirth were identified from a computerized hospital database, and pathological, clinical, and biochemical data were reviewed for all cases. Trends were analyzed using the Cusick test for trend. Categorical data were analyzed using the Fisher's exact test, with the 5% level considered significant. The incidence of intrauterine fetal demise at term was 1.8 per 1000 at-risk pregnancies. There was no significant downward trend in the rate of term stillbirth between 1996 and 2005 (p = 0.0808). Stillbirths were unexplained in 51% of cases, although in many cases a possible etiological factor was identified but not necessarily proven. There was a significant downward trend in the incidence of unexplained term stillbirths at our institution over the 10-year study period (p = 0.0105). Placental/cord factors accounted for 25% of term stillbirths and did not decrease significantly over the study period (p = 0.0953). Almost 50% of term stillbirths occurred in women who registered late or had no antenatal care. However, suboptimal antenatal care was not predictive of differences in either acceptance of perinatal postmortem or successful identification of stillbirth etiology. The incidence of stillbirth at term is 2 per 1000 term pregnancies and has not changed significantly in the past 10 years. Almost 50% of term stillbirths occurred in women with suboptimal antenatal care. More than half of cases are unexplained, often resulting from an incomplete diagnostic work-up. Despite this, there has been a significant downward trend in the rates of unexplained stillbirth at term. It is imperative that a complete diagnostic work-up is performed in

  10. The near-universal experience of regret among smokers in four countries: findings from the International Tobacco Control Policy Evaluation Survey.

    Science.gov (United States)

    Fong, Geoffrey T; Hammond, David; Laux, Fritz L; Zanna, Mark P; Cummings, K Michael; Borland, Ron; Ross, Hana

    2004-12-01

    Regret may be a key variable in understanding the experience of smokers, the vast majority of whom continue to smoke while desiring to quit. We present data from the baseline wave (October-December 2002) of the International Tobacco Control Policy Evaluation Survey, a random-digit-dialed telephone survey of a cohort of over 8,000 adult smokers across four countries--Canada, the United States, the United Kingdom, and Australia--to estimate the prevalence of regret and to identify its predictors. The proportion of smokers who agreed or agreed strongly with the statement "If you had to do it over again, you would not have started smoking" was extremely high--about 90%--and nearly identical across the four countries. Regret was more likely to be experienced by older smokers, women, those who had tried to quit more often, those who perceived quitting as conferring benefits, those with higher levels of perceived addiction, those who worried about future damage to health, those who perceived smoking as lowering their quality of life, those who perceived higher monetary costs of smoking, and those who believed that smoking is not socially acceptable. This predictive model was the same in all four countries. Regret is thus a near-universal experience among smokers in all four countries, and the factors that predict regret are universal across these four countries. Among other implications for cessation treatment and smoking prevention, this near universality of regret casts doubt on the view of some policy analysts and economists that the decisions to take up and continue smoking are welfare-maximizing for the consumer.

  11. Draft 1992 : Operations, Maintenance, and Replacement 10-Year Plan.

    Energy Technology Data Exchange (ETDEWEB)

    United States. Bonneville Power Administration.

    1992-05-01

    Two years ago, BPA released its first-ever Operations, Maintenance, and Replacement (OM R) 10-Year Plan. That effort broke new ground and was an extensive look at the condition of Operations, Maintenance, and Replacement on BPA's power system. This document -- the 1992 OM R 10-Year Plan -- uses that original plan as its foundation. It takes a look at how well BPA has accomplished the challenging task set out in the 1990 Plan. The 1992 Plan also introduces the Construction Program. Construction's critical role in these programs is explored, and the pressures of construction workload -- such as the seasonal nature of the work and the broad swings in workload between projects and years -- are discussed. The document then looks at how situations may have changed with issues explored initially in the 1990 Plan. Importantly, this Plan also surfaces and explains some new issues that threaten to impact BPA's ability to accomplish its OM R workload. Finally, the document focuses on the revised strategies for Operations, Maintenance, Replacement, Construction, and Environment for the 1992 to 2001 time period, including the financial and human resources needed to accomplish those strategies.

  12. Draft 1992 : Operations, Maintenance, and Replacement 10-Year Plan.

    Energy Technology Data Exchange (ETDEWEB)

    United States. Bonneville Power Administration.

    1992-05-01

    Two years ago, BPA released its first-ever Operations, Maintenance, and Replacement (OM&R) 10-Year Plan. That effort broke new ground and was an extensive look at the condition of Operations, Maintenance, and Replacement on BPA`s power system. This document -- the 1992 OM&R 10-Year Plan -- uses that original plan as its foundation. It takes a look at how well BPA has accomplished the challenging task set out in the 1990 Plan. The 1992 Plan also introduces the Construction Program. Construction`s critical role in these programs is explored, and the pressures of construction workload -- such as the seasonal nature of the work and the broad swings in workload between projects and years -- are discussed. The document then looks at how situations may have changed with issues explored initially in the 1990 Plan. Importantly, this Plan also surfaces and explains some new issues that threaten to impact BPA`s ability to accomplish its OM&R workload. Finally, the document focuses on the revised strategies for Operations, Maintenance, Replacement, Construction, and Environment for the 1992 to 2001 time period, including the financial and human resources needed to accomplish those strategies.

  13. Poor 10-year survivorship of hip resurfacing arthroplasty

    Science.gov (United States)

    Seppänen, Matti; Karvonen, Mikko; Virolainen, Petri; Remes, Ville; Pulkkinen, Pekka; Eskelinen, Antti; Liukas, Antti; Mäkelä, Keijo T

    2016-01-01

    Background and purpose In a previous registry report, short-term implant survival of hip resurfacing arthroplasty (HRA) in Finland was found to be comparable to that of total hip arthroplasty (THA). Since then, it has become evident that adverse reactions to metal debris (ARMDs) may also be associated with HRA, not only with large-diameter head metal-on-metal THA. The aim of the study was to assess medium- to long-term survivorship of HRA based on the Finnish Arthroplasty Register (FAR). Patients and methods 5,068 HRAs performed during the period 2001–2013 in Finland were included. Kaplan-Meier survival analysis was used to calculate survival probabilities and their 95% confidence intervals (CIs). Cox multiple regression, with adjustment for age, sex, diagnosis, femoral head size, and hospital volume was used to analyze implant survival of HRA devices with revision for any reason as endpoint. The reference group consisted of 6,485 uncemented Vision/Bimetric and ABG II THAs performed in Finland over the same time period. Results The 8-year survival, with any revision as an endpoint, was 93% (CI: 92–94) for Birmingham Hip Resurfacing (BHR), 86% (CI: 78–94) for Corin, 91% (CI: 89–94) for ReCap, 92% (CI: 89–96) for Durom, and was 72% (CI: 69–76) for the Articular Surface Replacement (ASR). The 10-year survival, with any revision as an endpoint, for reference THAs was 92% (CI: 91–92) and for all HRAs it was 86% (CI: 84–87%). Female HRA patients had about twice the revision risk of male patients. ASR had an inferior outcome: the revision risk was 4-fold higher than for BHR, the reference implant. Interpretation The 10-year implant survival of HRAs is 86% in Finland. According to new recommendations from NICE (The National Institute for Health and Care Excellence), an HRA/THA should have a revision rate of 5% or less at 10 years. None of the HRAs studied achieved this goal. PMID:27759474

  14. Polygonal triple (Kotz) osteotomy (over 10 years experience).

    Science.gov (United States)

    Sen, Cengiz; Gunes, Taner; Erdem, Mehmet; Ozger, Harzem; Tozun, I Remzi

    2007-06-01

    We evaluated the results of polygonal triple (Kotz) osteotomy for the treatment of acetabular dysplasia over 10 years. This study included 31 hips of 27 patients who had the Kotz osteotomy for acetabular dysplasia. The mean age was 21.5 years. We performed the original Kotz osteotomy for the first 22 hips (group I), while the modified Kotz osteotomy through an intra-pelvic approach without damage to the abductor muscle was applied for the last 9 hips (group II). Patients were evaluated by clinically and radiologically. The average follow-up was 106 months in group I, and 18 months in group II. The Trendelenburg gait was unchanged for four patients in group I and for one patient in group II. The Harris Hip Score improved in all patients postoperatively. Radiographic assesment showed improvement in both groups in terms of the angle of CE, VCE, and Sharp postoperatively(PTrendelenburg gait compared to the original Kotz osteotomy.

  15. Prenatal diagnosis of cystic fibrosis: 10-years experience.

    Science.gov (United States)

    Hadj Fredj, S; Ouali, F; Siala, H; Bibi, A; Othmani, R; Dakhlaoui, B; Zouari, F; Messaoud, T

    2015-06-01

    We present in this study our 10years experience in prenatal diagnosis of cystic fibrosis performed in the Tunisian population. Based on family history, 40 Tunisian couples were selected for prenatal diagnosis. Fetal DNA was isolated from amniotic fluid collected by transabdominal amniocentesis or from chronic villi by transcervical chorionic villus sampling. The genetic analysis for cystic fibrosis mutations was performed by denaturant gradient gel electrophoresis and denaturing high-pressure liquid phase chromatography. We performed microsatellites analysis by capillary electrophoresis in order to verify the absence of maternal cell contamination. Thirteen fetuses were affected, 21 were heterozygous carriers and 15 were healthy with two normal alleles of CFTR gene. Ten couples opted for therapeutic abortion. The microsatellites genotyping showed the absence of contamination of the fetal DNA by maternal DNA in 93.75%. Our diagnostic strategy provides rapid and reliable prenatal diagnosis at risk families of cystic fibrosis. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  16. 10 year course of IQ in first-episode psychosis

    DEFF Research Database (Denmark)

    Barder, Helene Eidsmo; Sundet, Kjetil; Rund, Bjørn Rishovd

    2015-01-01

    are largely uninvestigated, but may identify subgroups with different intellectual trajectories. Eighty-nine first-episode psychosis patients were investigated on IQ at baseline and at 10-years follow-up. Total time in psychosis was defined as two separate variables; Duration of psychosis before start...... of treatment (i.e. duration of untreated psychosis: DUP), and duration of psychosis after start of treatment (DAT). The sample was divided in three equal groups based on DUP and DAT, respectively. To investigate if diagnosis could separate IQ-trajectories beyond that of psychotic duration, two diagnostic...... categories were defined: core versus non-core SSDs. No significant change in IQ was found for the total sample. Intellectual course was not related to DUP or stringency of diagnostic category. However, a subgroup with long DAT demonstrated a significant intellectual decline, mainly associated with a weaker...

  17. Omental infarction in an obese 10-year-old boy

    Directory of Open Access Journals (Sweden)

    Katerina Kambouri

    2011-09-01

    Full Text Available Primary omental infarction (POI has a low incidence worldwide, with most cases occurring in adults. This condition is rarely considered in the differential diagnosis of acute abdominal pain in childhood. Herein, we present a case of omental infarction in an obese 10-year-old boy who presented with acute abdominal pain in the right lower abdomen. The ultrasound (US examination did not reveal the appendix but showed secondary signs suggesting acute appendicitis. The child was thus operated on under the preoperative diagnosis of acute appendicitis but the intraoperative finding was omental infarct. Since the omental infarct as etiology of acute abdominal pain is uncommon, we highlight some of the possible etiologies and emphasize the importance of accurate diagnosis and appropriate treatment of omental infarction.

  18. Cystic fibrosis school for 10-year-olds

    DEFF Research Database (Denmark)

    Bregnballe, Vibeke; Schiøtz, Peter Oluf

    2000-01-01

    on which they can make their own choices in order to improve their quality of life. In practical terms we make classes of 4-8 10-year-old children with CF. We give them 6 lessons of 3 hours. One lesson every second month. The lessons substitute a monthly visit. The psysiotherapist and the nurse teach...... give them a good basis on which they can make their own choices about how they want to live their lives with cystic fibrosis and with optimal quality of life.......Compliance or rather lack of compliance has always been a problem when treating patients with cystic fibrosis. The patients tend to drop the treatment more or less if the treatment gets too complicated or laboured. We have attempted a systematical education of our patients in a CF school...

  19. Class III treatment using facial mask: Stability after 10 years

    Directory of Open Access Journals (Sweden)

    Adilson Luiz Ramos

    2014-10-01

    Full Text Available Early Class III malocclusion treatment may not have long-term stability due to mandibular growth. Although some features of this malocclusion point to a better prognosis, it is practically impossible for the orthodontist to foresee cases that require new intervention. Many patients need retreatment, whether compensatory or orthodontic-surgical. The present study reports the case of a Class III patient treated at the end of the mixed dentition with the use of a face mask followed by conventional fixed appliances. The case remains stable 10 years after treatment completion. It was presented to the Brazilian Board of Orthodontics and Dentofacial Orthopedics (BBO as a requirement for the title of certified by the BBO.

  20. ESO and Chile: 10 Years of Productive Scientific Collaboration

    Science.gov (United States)

    2006-06-01

    ESO and the Government of Chile launched today the book "10 Years Exploring the Universe", written by the beneficiaries of the ESO-Chile Joint Committee. This annual fund provides grants for individual Chilean scientists, research infrastructures, scientific congresses, workshops for science teachers and astronomy outreach programmes for the public. In a ceremony held in Santiago on 19 June 2006, the European Organisation for Astronomical Research in the Southern Hemisphere (ESO) and the Chilean Ministry of Foreign Affairs marked the 10th Anniversary of the Supplementary Agreement, which granted to Chilean astronomers up to 10 percent of the total observing time on ESO telescopes. This agreement also established an annual fund for the development of astronomy, managed by the so-called "ESO-Chile Joint Committee". ESO PR Photo 21/06 ESO PR Photo 21/06 Ten Years ESO-Chile Agreement Ceremony The celebration event was hosted by ESO Director General, Dr. Catherine Cesarsky, and the Director of Special Policy for the Chilean Ministry of Foreign Affairs, Ambassador Luis Winter. "ESO's commitment is, and always will be, to promote astronomy and scientific knowledge in the country hosting our observatories", said ESO Director General, Dr. Catherine Cesarsky. "We hope Chile and Europe will continue with great achievements in this fascinating joint adventure, the exploration of the universe." On behalf of the Government of Chile, Ambassador Luis Winter outlined the historical importance of the Supplementary Agreement, ratified by the Chilean Congress in 1996. "Such is the magnitude of ESO-Chile Joint Committee that, only in 2005, this annual fund represented 8 percent of all financing sources for Chilean astronomy, including those from Government and universities", Ambassador Winter said. The ESO Representative and Head of Science in Chile, Dr. Felix Mirabel, and the appointed Chilean astronomer for the ESO-Chile Joint Committee, Dr. Leonardo Bronfman, also took part in the

  1. 10 years of Terra Outreach over the Internet

    Science.gov (United States)

    Yuen, K.; Riebeek, H.; Chambers, L. H.

    2009-12-01

    1 Author Yuen, Karen JPL (818) 393-7716 2 Author Riebeek, Holli Sigma Space Corporation (department) at NASA Goddard Space Flight Center (Institution), Greenbelt, Maryland 3 Author Chambers, Lin NASA Abstract: Since launch, Terra has returned about 195 gigabytes (level 0) of data per day or 1 terabyte every 5 days. Few outlets were able to accommodate and quickly share that amount of information as well as the Internet. To honor the 10-year anniversary of the launch of Terra, we would like to highlight the education and outreach efforts of the Terra mission on the Internet and its reach to the science attentive public. The Internet or web has been the primary way of delivering Terra content to different groups- from formal and informal education to general public outreach. Through the years, many different web-based projects have been developed, and they were of service to a growing population of the science attentive public. One of Terra’s original EPO activities was the Earth Observatory. It was initially dedicated to telling the remote sensing story of Terra, but quickly grew to include science and imagery from other sensors. The web site allowed for collaboration across NASA centers, universities and other organizations by exchanging and sharing of story ideas, news and images. The award winning Earth Observatory helped pave the way for the more recently funded development of the Climate Change website. With its specific focus on climate change studies, once again, Terra stories and images are shared with an even more specific audience base. During the last 10 years, Terra as a mission has captured the imagination of the public through its visually stunning and artistically arresting images. With its five instruments of complementary but unique capabilities, the mission gave the world not just pretty pictures, but scientific data-based images. The world was able to see from space everything from calving icebergs to volcanic eruption plumes and the eye of a

  2. METEONETWORK: 2002-2012, 10 years of activities

    Science.gov (United States)

    Mazza, Edoardo

    2013-04-01

    The role of citizen-scientists in collecting data and observations has been increasingly crucial in the last 10 years of atmospheric sciences. Meteonetwork is a non-profit organization founded by citizen scientists in 2002, in Lombardia, with the aim of raising public awareness about meteorological and climatological issues. Throughout the years the organization, besides the continuous holding of events such as meeting, conferences and talks, has been standing out because of its forum and its wide network of weather stations. Meteonetwork's forum is, in this field, the most read and followed in the country and with its 8459 members and over 4,217,505 posts turns out to be the 17th forum over the entire country. Its network is operated in cooperation with Centro Epson Meteo and collects amateur semi-professional stations distributed all over the Italian territory, providing real-time and daily data. It consists of 706 stations, among which more than 400 regularly updated; volunteers constantly work to perform quality control and ensure data reliability. Meteonetwork has also developed several collaborations with private and public institutions, among which DRIHM - Cima Research Foundation, Centro Epson Meteo di Milano, Arpa Veneto, Arpa Emilia-Romagna, Arpa Lombardia, Arpa Friuli - Venezia Giulia, Servizio Glaciologico Lombardo, C. N. R. - C. I. S. A, Università di Pisa, Università di Milano, University of Aberdeen, Protezione Civile - Regione Lombardia, Protezione Civile - Regione Piemonte stand out. As WMO emphasized in 2001 World Meteorological Day "Volunteers for the weather, climate and water" the contribution of citizen-scientists to scientific studies is remarkable. In this perspective Meteonetwork and the University of Milan, in April 2011, started a project of technical and scientific cooperation called Weatherness. The university is provided with data gathered by Meteoneonetwork's stations with the aim of improving the knowledge of the impact that heat

  3. A 10-year retrospective study on odontogenic tumors in Iran

    Directory of Open Access Journals (Sweden)

    Nasim Taghavi

    2013-01-01

    Full Text Available Objective: The aim of this study was to review cases of odontogenic tumors diagnosed in two pathology centers in Tehran, Iran, during a 10-year period. Study Design: Patients′ records were seen at two teaching pathology Centre′s of Shahid Beheshti University between the months of March 2000 to 2010 with histologic diagnosis of any type of odontogenic tumors. The records were analyzed for frequency, age, sex, site, as well as clinical, radiographic and histopathologic findings. Results: Of 30706 biopsies, 4767 (15.5% cases were diagnosed as oral and maxillofacial lesions. Among these, 720 cases were tumoral with 188 (26.1% cases of odontogenic tumors. Tumors with odontogenic epithelium origin formed 70.2% of total numbers of odontogenic tumors. Mixed odontogenic tumors and tumors of odontogenic ectomesenchyme comprised 12.2% and 17.5% of the cases respectively. Ameloblastoma, with a frequency of 62.2% was the most common tumor in this review which was followed by odontoma and odontogenic myxoma. Conclusion: Although there are few studies on odontogenic tumors in literature, the comparison of our results with existing data shows significant differences in the distribution of tumors and age of patients, which may be due to ethnic features and geographic distribution of patients. Future studies on other ethnic groups are essential for further clarification of the findings in this research.

  4. In Brief: Chandra Observatory marks 10 years in space

    Science.gov (United States)

    Showstack, Randy

    2009-08-01

    NASA's Chandra X-ray Observatory, originally envisioned as a 5-year mission, was deployed into an elliptical orbit around Earth 10 years ago, on 23 July 1999. The most powerful X-ray telescope yet, Chandra has provided a peak into the high-energy universe and has independently confirmed the existence of dark energy. Martin Weisskopf, Chandra project scientist at NASA's Marshall Space Flight Center, Huntsville, Ala., said discoveries made possible by the observatory “have made dramatic changes to our understanding of the universe and its constituents.” “The Great Observatories program—of which Chandra is a major part—shows how astronomers need as many tools as possible to tackle the big questions out there,” said Ed Weiler, associate administrator of NASA's Science Mission Directorate at NASA Headquarters in Washington. The Hubble Space Telescope, Compton Gamma Ray Observatory, and Spitzer Space Telescope are NASA's other Great Observatories. For more information, visit http://chandra.harvard.edu/ten/ and http://chandra.nasa.gov.

  5. Fractures of the mandible and maxilla: A 10-year analysis

    Directory of Open Access Journals (Sweden)

    Estie Kruger

    2016-01-01

    Full Text Available Background Previous analysis of jaw fracture hospitalisations in Western Australia (WA indicated disproportionately high rates of hospitalisations for Aboriginal people. This study was to follow-up on the earlier analysis to determine if inequalities in terms of jaw fracture hospitalisation rates between Aboriginal and non-Aboriginal people have changed. Aims This study, done over a 10-year period from 1999/2000 to 2008/2009, aimed to determine rates of hospitalisations for jaw fractures in WA, trends over the 10–year period, and direct costs associated with these hospital admissions. Methods Hospitalisation data were obtained from the Western Australian Hospital Morbidity Data System (HMDS. Episodes were selected on the basis of an ICD10-AM code being S02.4 (Fracture of the malar and maxillary bones and S02.6 (Fracture of the mandible. Self-reported Aboriginality were used to compare Aboriginal to non-Aboriginal populations. Estimated cost of care was determined for each episode using the national standard diagnostic-related group (DRG average price. Results Our findings indicate that inequalities between Aboriginal and non-Aboriginal people in terms of hospital admissions for jaw fractures exist in WA, and continued over a decade-long period. Higher fracture rates occurred amongst males, Aboriginal people, younger adult age-groups, those from low socioeconomic areas, and those from remote and very remote areas. The DRG cost per person for jaw fractures ranged between AUD $842 and $109,002, with a median cost of $4,965. Conclusion Hospital admission rates for the treatment of maxillary and mandibular fractures is very strongly divided along racial and socioeconomic lines in WA.

  6. Click Chemistry and Radiochemistry: The First 10 Years.

    Science.gov (United States)

    Meyer, Jan-Philip; Adumeau, Pierre; Lewis, Jason S; Zeglis, Brian M

    2016-12-21

    The advent of click chemistry has had a profound influence on almost all branches of chemical science. This is particularly true of radiochemistry and the synthesis of agents for positron emission tomography (PET), single photon emission computed tomography (SPECT), and targeted radiotherapy. The selectivity, ease, rapidity, and modularity of click ligations make them nearly ideally suited for the construction of radiotracers, a process that often involves working with biomolecules in aqueous conditions with inexorably decaying radioisotopes. In the following pages, our goal is to provide a broad overview of the first 10 years of research at the intersection of click chemistry and radiochemistry. The discussion will focus on four areas that we believe underscore the critical advantages provided by click chemistry: (i) the use of prosthetic groups for radiolabeling reactions, (ii) the creation of coordination scaffolds for radiometals, (iii) the site-specific radiolabeling of proteins and peptides, and (iv) the development of strategies for in vivo pretargeting. Particular emphasis will be placed on the four most prevalent click reactions-the Cu-catalyzed azide-alkyne cycloaddition (CuAAC), the strain-promoted azide-alkyne cycloaddition (SPAAC), the inverse electron demand Diels-Alder reaction (IEDDA), and the Staudinger ligation-although less well-known click ligations will be discussed as well. Ultimately, it is our hope that this review will not only serve to educate readers but will also act as a springboard, inspiring synthetic chemists and radiochemists alike to harness click chemistry in even more innovative and ambitious ways as we embark upon the second decade of this fruitful collaboration.

  7. 10-year ionospheric equivalent current statistics from the ECLAT project

    Science.gov (United States)

    Kauristie, Kirsti; Vanhamäki, Heikki; Viljanen, Ari; Van de Kamp, Max; Juusola, Liisa; Partamies, Noora; Amm, Olaf; Zivkovic, Tatjana; Ågren, Karin; Opgenoorth, Hermann

    2013-04-01

    The ECLAT (European Cluster Assimilation Technology,) is an EU FP7 project which develops value added data products to support the Cluster Active Archive (CAA). The supporting data set will include 10 years of spatial maps of ionospheric equivalent currents (Jeq) calculated from the data of the magnetometers in the MIRACLE network operated in the Fennoscandian mainland and extending poleward until Svalbard. The Jeq database combined with the other data in Cluster Active Archive will offer a unique opportunity to conduct statistical studies on ionospheric current systems and their linkage with different magnetospheric processes. In this presentation we will introduce the process used to generate the Jeq data base, demonstrate how Jeq data can be browsed with an on-line tool and show some examples how the data can be used in magnetosphere-ionosphere coupling studies. In particular, we will show results from a preliminary study where Jeq recorded during 2003 are used to study the spatial distribution of Jeq and its curl (which in certain conditions can be used as a proxy for field-aligned currents) in different geophysical conditions. With this example we want to emphasize that the ECLAT Jeq database, in contrast to previously used data bases (e.g. from LEO satellites), is constructed from a 2-dimensional magnetometer network, which allows statistical studies on the horizontal gradients of Jeq in both latitudinal and longitudinal directions simultaneously. More information about ECLAT and the associated data archives is available from the following links: http://www.space.irfu.se/ECLAT/eclat-web/eclat_detail.html; http://caa.estec.esa.int/; http://www.space.fmi.fi/MIRACLE/; http://www.space.fmi.fi/image/.

  8. The management of HIV in pregnancy: A 10-year experience.

    Science.gov (United States)

    Raffe, Sonia F; Savage, Charlotte; Perry, Louisa A; Patel, Amie; Keith, Tricia; Howell, Richard; Bradley, Robert; Bomont, Rob; Fidler, Katy; Gilleece, Yvonne

    2017-03-01

    The package of care to reduce HIV mother to child transmission (MTCT) has evolved significantly since trials of ante and intrapartum antiretroviral therapy (ART) in 1994. In the UK MTCT rate has fallen from 25.6% in the 1990s to 0.46%. We review the management of HIV in pregnancy in Brighton in the context of evolving guidelines. HIV, obstetric and neonatal notes of all HIV positive women, pregnant between 2003 and 2014, were reviewed. 97 pregnancies in 75 women were identified, resulting in 79 live births. Antenatal HIV diagnosis was made in 22 (28%). The proportion of pregnancies in those with known HIV at conception increased over the time period. At conception 58 (60%) were on ART, 33 (57%) of who continued on their original regimen. 34 (35%) initiated ART following conception: 14 known to be HIV positive, 20 diagnosed during pregnancy. Two did not start ART (1 due to miscarriage, 1 as diagnosed post-delivery) and in three cases ART history was unavailable due to transfer to alternative centres. ART was initiated on average at 22 weeks gestation (range 6-34). 4(5%) received Zidovudine (AZT) monotherapy, all before 2006. Choice of combination ART (cART) varied with time reflecting changing guidelines. Prior to 2008 an AZT containing regimen was used in 83% versus 8% after. Planned mode of delivery was documented in 73: 30(41%) planned a normal vaginal delivery (NVD), 43(59%) a caesarean section (CS). The viral load (VL) was <50copies/mL in 58(76%) at 36 weeks and 64(84%) at delivery. 90% with a detectable VL at 36 weeks delivered via CS. 100% received neonatal post-exposure prophylaxis (PEP): 68(88%) AZT monotherapy, 9(12%) cART. 84% initiated PEP within four hours. 90% completed 28days. 8(10%) babies experienced side effects. In the 10-year review period, one infant (1.3%) was diagnosed HIV positive. Both mother and infant received care in accordance with guidelines, including neonatal PEP within 4hours. Care of the HIV positive pregnant woman in Brighton has

  9. TIPSS: 10 years of experience; TIPSS: 10 Jahre klinische Erfahrung

    Energy Technology Data Exchange (ETDEWEB)

    Richter, G.M.; Brado, M.; Simon, C.; Radeleff, B.; Kauffmann, G.W. [Heidelberg Univ. (Germany). Abt. Radiodiagnostik; Noeldge, G.; Scharf, J.; Hansmann, J.

    1998-04-01

    Purpose: To demonstrate and document 10 years of clinical experience gathered by us with TIPSS and to discuss achievements, problems and outlook. Results: Variceal filling was widely reduced by TIPSS, and significantly reduced portal liver perfusion as assessed morphologically and rheologically. However, there was an immediate onset of compensated liver perfusion by increased arterial inflow. Total liver perfusion did not change significantly. In TIPSS portal decompression was readily achieved, the portosystemic gradient dropping from an average of 24 mm Hg to 10.5 mm Hg. In our series we could not demonstrate an increased incidence of hepatic encephalopathy during the 30-day post-TIPSS period. Early mortality was 4% and early rebleeding rate 3%. The 12-month re-intervention rate based on an invasive portography follow-up protocol was 76%, and the 24-month re-intervention rate was 90%. The definite occlusion rate was below 5%. Beyond a follow-up time span of 24-months the necessity for re-intervention dropped significantly: Less than one-third of our patients required some sort of re-intervention. (orig./AJ) [Deutsch] Ziel: Darstellung der nach 10jaehriger klinischer Anwendung von TIPSS gewonnenen Erfahrungen unter Beruecksichtigung der technischen Grundlagen, der Veraenderungen in der Haemodynamik der Leber und der Langzeitergebnisse. Ergebnisse: TIPSS reduziert die Varizenfuellung und verringert morphologisch und haemodynamisch die portale Perfusion. Die Gesamtleberperfusion aendert sich nicht signifikant. Unter TIPSS kommt es zu einer unmittelbaren Zunahme der arteriellen Leberperfusion. Die portale Drucksenkung erfolgt von einem portosystemischen Mitteldruck von 24 mmHg auf 10,5 mmHg im Durchschnitt. Die spontane hepatische Enzephalopathierate von etwa 20% aendert sich durch TIPSS nicht wesentlich. Die Fruehletalitaet betraegt 4% und die Nachblutungsrate 3%. Insbesondere die Standardisierung von Indikationen und Kontraindikationen, des Punktionsbesteckes, der

  10. The GLOBE Program 10 Years On: Challenges and Opportunities

    Science.gov (United States)

    Blurton, C.

    2004-12-01

    ). This session will examine what was accomplished during GLOBE's first 10 years as a Federal program, what challenges the Program faces, and what plans are afoot for GLOBE's next ten years under UCAR's leadership.

  11. Prepaid monetary incentives—Predictors of taking the money and completing the survey: Results from the International Tobacco Control (ITC) Four Country Survey

    Science.gov (United States)

    Mutti, Seema; Kennedy, Ryan David; Thompson, Mary E.; Fong, Geoffrey T.

    2015-01-01

    Prepaid monetary incentives are used to address declining response rates in random-digit-dial surveys. There is concern among researchers that some respondents will accept the prepayment but not complete the survey. There is little research to understand check cashing and survey completing behaviors among respondents who receive pre-payment. Data from the International Tobacco Control Four Country Study—a longitudinal survey of smokers in Canada, the US, the UK, and Australia, were used to examine the impact of prepayment (in the form of checks, approximately $10USD) on sample profile. Approximately 14% of respondents cashed their check, but did not complete the survey, while about 14% did not cash their checks, but completed the survey. Younger adults (Canada, US), those of minority status (US), and those who had been in the survey for only two waves or less (Canada, US) were more likely to cash their checks and not complete the survey. PMID:26778862

  12. Prepaid monetary incentives-Predictors of taking the money and completing the survey: Results from the International Tobacco Control (ITC) Four Country Survey.

    Science.gov (United States)

    Mutti, Seema; Kennedy, Ryan David; Thompson, Mary E; Fong, Geoffrey T

    2014-05-01

    Prepaid monetary incentives are used to address declining response rates in random-digit-dial surveys. There is concern among researchers that some respondents will accept the prepayment but not complete the survey. There is little research to understand check cashing and survey completing behaviors among respondents who receive pre-payment. Data from the International Tobacco Control Four Country Study-a longitudinal survey of smokers in Canada, the US, the UK, and Australia, were used to examine the impact of prepayment (in the form of checks, approximately $10USD) on sample profile. Approximately 14% of respondents cashed their check, but did not complete the survey, while about 14% did not cash their checks, but completed the survey. Younger adults (Canada, US), those of minority status (US), and those who had been in the survey for only two waves or less (Canada, US) were more likely to cash their checks and not complete the survey.

  13. Effects of the 2003 advertising/promotion ban in the United Kingdom on awareness of tobacco marketing: findings from the International Tobacco Control (ITC) Four Country Survey.

    Science.gov (United States)

    Harris, F; MacKintosh, A M; Anderson, S; Hastings, G; Borland, R; Fong, G T; Hammond, D; Cummings, K M

    2006-06-01

    In February 2003, a comprehensive ban on tobacco promotion came into effect in the United Kingdom, which prohibited tobacco marketing through print and broadcast media, billboards, the internet, direct mail, product placement, promotions, free gifts, coupons and sponsorships. To investigate the impact of the UK's comprehensive ban on tobacco promotion on adult smokers' awareness of tobacco marketing in the UK relative to Canada, the United States and Australia. A total of 6762 adult smokers participated in two waves of a random digit dialled telephone survey across the four countries. Wave 1 was conducted before the UK ban (October-December 2002) and Wave 2 was conducted after the UK ban (May-September 2003). Awareness of a range of forms of tobacco marketing. Levels of tobacco promotion awareness declined significantly among smokers in the UK after implementation of the advertising ban. Declines in awareness were greater in those channels regulated by the new law and change in awareness of tobacco promotions was much greater in the UK than the other three countries not affected by the ban. At least in the short term, there was no evidence that the law resulted in greater exposure to tobacco promotions in the few media channels not covered by the law. Notwithstanding the apparent success of the UK advertising ban and the controls in other countries, 9-22% of smokers in the four countries still reported noticing things that promoted smoking "often or very often" at Wave 2. The UK policy to ban tobacco advertising and promotion has significantly reduced exposure to pro-tobacco marketing influences. These findings support the effectiveness of comprehensive bans on advertising and promotion, as included in the Framework Convention on Tobacco Control.

  14. Young men who have sex with men's use of social and sexual media and sex-risk associations: cross-sectional, online survey across four countries.

    Science.gov (United States)

    Lorimer, Karen; Flowers, Paul; Davis, Mark; Frankis, Jamie

    2016-08-01

    There has been an increase in new HIV diagnoses among young men who have sex with men (YMSM) over the past decade in both UK and US contexts, with online sex-seeking implicated in driving this development. This study sought to examine YMSM's use of a variety of social and sexual networking websites and 'apps', and assess sexual risk behaviours. YMSM were recruited from across four countries in Britain and Ireland, via an online survey using convenience sampling. Data were collected from 2668 men, of whom 702 were aged 18-25 years. Facebook use was almost ubiquitous and for largely social reasons; sexual media use was common with 52% using gay sexual networking (GSN) websites frequently and 44% using similar apps frequently. We found increased odds of high-risk condomless anal intercourse associated with the length of time users had been using GSN websites and lower levels of education. We found no significant differences across the four countries in sexual risk behaviours. YMSM are a heterogeneous population with varied sexual health needs. For young men with digital literacy, individual-level online interventions, targeted and tailored, could be directed towards frequent users with lower levels of education. Variation in demographic characteristics of GSN websites and app users may affect who interventions are likely to reach, depending on where they are targeted. However, interventions, which may catch young men earlier, also provide a major opportunity for reducing sexual health inequalities. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  15. Predictors and longitudinal course of cognitive functioning in schizophrenia spectrum disorders, 10 years after baseline

    DEFF Research Database (Denmark)

    Bergh, Sara; Hjorthøj, Carsten; Sørensen, Holger J.

    2016-01-01

    baseline. Uni- and multi-variable regression analyses of potential baseline predictors of 10-year CF were performed. Also, changes in CF and symptomatology between 5 and 10years of follow-up were assessed. FINDINGS: Baseline predictors of impaired CF after 10years included male gender, unemployment, poor...

  16. Arsenic Exposure and Predicted 10-Year Atherosclerotic Cardiovascular Risk Using the Pooled Cohort Equations in U.S. Hypertensive Adults.

    Science.gov (United States)

    Nong, Qingjiao; Zhang, Yiyi; Guallar, Eliseo; Zhong, Qiuan

    2016-11-07

    This study was to evaluate the association of urine arsenic with predicted 10-year atherosclerotic cardiovascular disease (ASCVD) risk in U.S. adults with hypertension. Cross-sectional analysis was conducted in 1570 hypertensive adults aged 40-79 years in the 2003-2012 National Health and Nutrition Examination Survey (NHANES) with determinations of urine arsenic. Predicted 10-year ASCVD risk was estimated by the Pooled Cohort Equations, developed by the American College of Cardiology/American Heart Association in 2013. For men, after adjustment for sociodemographic factors, urine dilution, ASCVD risk factors and organic arsenic intake from seafood, participants in the highest quartiles of urine arsenic had higher 10-year predicted ASCVD risk than in the lowest quartiles; the increases were 24% (95% confidence interval (CI): 2%, 53%) for total arsenic, 13% (95% CI: 2%, 25%) for dimethylarsinate and 22% (95% CI: 5%, 40%) for total arsenic minus arsenobetaine separately. For women, the corresponding increases were 5% (95% CI: -15%, 29%), 10% (95% CI: -8%, 30%) and 0% (95% CI: -15%, 19%), respectively. Arsenic exposure, even at low levels, may contribute to increased ASCVD risk in men with hypertension. Furthermore, our findings suggest that particular circumstances need urgently to be considered while elucidating cardiovascular effects of low inorganic arsenic levels.

  17. The Effectiveness of Tobacco Marketing Regulations on Reducing Smokers’ Exposure to Advertising and Promotion: Findings from the International Tobacco Control (ITC Four Country Survey

    Directory of Open Access Journals (Sweden)

    K. Michael Cummings

    2011-01-01

    Full Text Available Exposure to tobacco product marketing promotes the initiation, continuation, and reuptake of cigarette smoking and as a result the World Health Organization Framework Convention on Tobacco Control (WHO FCTC has called upon member Parties to enact comprehensive bans on tobacco advertising and promotion. This study examines the immediate and long term effectiveness of advertising restrictions enacted in different countries on exposure to different forms of product marketing, and examines differences in exposure across different socioeconomic status (SES groups. Nationally representative data from the United Kingdom, Canada, Australia, and the United States, collected from adult smokers between 2002 and 2008 using the International Tobacco Control Four Country Survey (ITC-4, were used in this study (N = 21,615. In light of the specific marketing regulation changes that occurred during the course of this study period, changes in awareness of tobacco marketing via various channels were assessed for each country, and for different SES groups within countries. Tobacco marketing regulations, once implemented, were associated with significant reductions in smokers’ reported awareness of pro-smoking cues, and the observed reductions were greatest immediately following the enactment of regulations. Changes in reported awareness were generally the same across different SES groups, although some exceptions were noted. While tobacco marketing regulations have been effective in reducing exposure to certain types of product marketing there still remain gaps, especially with regard to in-store marketing and price promotions.

  18. The effectiveness of tobacco marketing regulations on reducing smokers' exposure to advertising and promotion: findings from the International Tobacco Control (ITC) Four Country Survey.

    Science.gov (United States)

    Kasza, Karin A; Hyland, Andrew J; Brown, Abraham; Siahpush, Mohammad; Yong, Hua-Hie; McNeill, Ann D; Li, Lin; Cummings, K Michael

    2011-02-01

    Exposure to tobacco product marketing promotes the initiation, continuation, and reuptake of cigarette smoking and as a result the World Health Organization Framework Convention on Tobacco Control (WHO FCTC) has called upon member Parties to enact comprehensive bans on tobacco advertising and promotion. This study examines the immediate and long term effectiveness of advertising restrictions enacted in different countries on exposure to different forms of product marketing, and examines differences in exposure across different socioeconomic status (SES) groups. Nationally representative data from the United Kingdom, Canada, Australia, and the United States, collected from adult smokers between 2002 and 2008 using the International Tobacco Control Four Country Survey (ITC-4), were used in this study (N = 21,615). In light of the specific marketing regulation changes that occurred during the course of this study period, changes in awareness of tobacco marketing via various channels were assessed for each country, and for different SES groups within countries. Tobacco marketing regulations, once implemented, were associated with significant reductions in smokers' reported awareness of pro-smoking cues, and the observed reductions were greatest immediately following the enactment of regulations. Changes in reported awareness were generally the same across different SES groups, although some exceptions were noted. While tobacco marketing regulations have been effective in reducing exposure to certain types of product marketing there still remain gaps, especially with regard to in-store marketing and price promotions.

  19. The relation between number of smoking friends, and quit intentions, attempts, and success: findings from the International Tobacco Control (ITC) Four Country Survey.

    Science.gov (United States)

    Hitchman, Sara C; Fong, Geoffrey T; Zanna, Mark P; Thrasher, James F; Laux, Fritz L

    2014-12-01

    Smokers who inhabit social contexts with a greater number of smokers may be exposed to more positive norms toward smoking and more cues to smoke. This study examines the relation between number of smoking friends and changes in number of smoking friends, and smoking cessation outcomes. Data were drawn from Wave 1 (2002) and Wave 2 (2003) of the International Tobacco Control (ITC) Project Four Country Survey, a longitudinal cohort survey of nationally representative samples of adult smokers in Australia, Canada, United Kingdom, and United States (N = 6,321). Smokers with fewer smoking friends at Wave 1 were more likely to intend to quit at Wave 1 and were more likely to succeed in their attempts to quit at Wave 2. Compared with smokers who experienced no change in their number of smoking friends, smokers who lost smoking friends were more likely to intend to quit at Wave 2, attempt to quit between Wave 1 and Wave 2, and succeed in their quit attempts at Wave 2. Smokers who inhabit social contexts with a greater number of smokers may be less likely to successfully quit. Quitting may be particularly unlikely among smokers who do not experience a loss in the number of smokers in their social context.

  20. General parenting styles are not strongly associated with fruit and vegetable intake and social-environmental correlates among 11-year-old children in four countries in Europe.

    Science.gov (United States)

    De Bourdeaudhuij, I; Te Velde, S J; Maes, L; Pérez-Rodrigo, C; de Almeida, M D V; Brug, J

    2009-02-01

    To investigate whether fruit and vegetable (F&V) intake in 11-year-olds, and social-environmental correlates of F&V intake such as parental modelling and encouragement, family food rules and home availability, differ according to general parenting styles in Belgium, The Netherlands, Portugal and Spain. Cross-sectional study. Primary schools in four countries. Pupils and one of their parents completed questionnaires to measure F&V intake, related social-environmental correlates and general parenting styles. The sample size was 4555 (49.3 % boys); 1180 for Belgium, 883 for The Netherlands, 1515 for Portugal and 977 for Spain. Parenting styles were divided into authoritative, authoritarian, indulgent and neglectful. No differences were found in F&V intake across parenting styles and only very few significant differences in social-environmental correlates. The authoritarian (more parental encouragement and more demands to eat fruit) and the authoritative (more availability of fruit and vegetables) parenting styles resulted in more favourable correlates. Despite earlier studies suggesting that general parenting styles are associated with health behaviours in children, the present study suggests that this association is weak to non-existent for F&V intakes in four different European countries.

  1. Patterns of cognitive dissonance-reducing beliefs among smokers: a longitudinal analysis from the International Tobacco Control (ITC) Four Country Survey.

    Science.gov (United States)

    Fotuhi, Omid; Fong, Geoffrey T; Zanna, Mark P; Borland, Ron; Yong, Hua-Hie; Cummings, K Michael

    2013-01-01

    The purpose of this paper is to assess whether smokers adjust their beliefs in a pattern that is consistent with Cognitive Dissonance Theory. This is accomplished by examining the longitudinal pattern of belief change among smokers as their smoking behaviours change. A telephone survey was conducted of nationally representative samples of adult smokers from Canada, the USA, the UK and Australia from the International Tobacco Control Four Country Survey. Smokers were followed across three waves (October 2002 to December 2004), during which they were asked to report on their smoking-related beliefs and their quitting behaviour. Smokers with no history of quitting across the three waves exhibited the highest levels of rationalisations for smoking. When smokers quit smoking, they reported having fewer rationalisations for smoking compared with when they had previously been smoking. However, among those who attempted to quit but then relapsed, there was once again a renewed tendency to rationalise their smoking. This rebound in the use of rationalisations was higher for functional beliefs than for risk-minimising beliefs, as predicted by social psychological theory. Smokers are motivated to rationalise their behaviour through the endorsement of more positive beliefs about smoking, and these beliefs change systematically with changes in smoking status. More work is needed to determine if this cognitive dissonance-reducing function has an inhibiting effect on any subsequent intentions to quit.

  2. Maintenance of antifracture efficacy over 10 years with strontium ranelate in postmenopausal osteoporosis.

    Science.gov (United States)

    Reginster, J-Y; Kaufman, J-M; Goemaere, S; Devogelaer, J P; Benhamou, C L; Felsenberg, D; Diaz-Curiel, M; Brandi, M-L; Badurski, J; Wark, J; Balogh, A; Bruyère, O; Roux, C

    2012-03-01

    In an open-label extension study, BMD increased continuously with strontium ranelate over 10 years in osteoporotic women (P TROPOS to 5 years were invited to enter a 5-year open-label extension, during which they received strontium ranelate 2 g/day (n = 237, 10-year population). Bone mineral density (BMD) and fracture incidence were recorded, and FRAX® scores were calculated. The effect of strontium ranelate on fracture incidence was evaluated by comparison with a FRAX®-matched placebo group identified in the TROPOS placebo arm. The patients in the 10-year population had baseline characteristics comparable to those of the total SOTI/TROPOS population. Over 10 years, lumbar BMD increased continuously and significantly (P < 0.01 versus previous year) with 34.5 ± 20.2% relative change from baseline to 10 years. The incidence of vertebral and nonvertebral fracture with strontium ranelate in the 10-year population in years 6 to 10 was comparable to the incidence between years 0 and 5, but was significantly lower than the incidence observed in the FRAX®-matched placebo group over 5 years (P < 0.05); relative risk reductions for vertebral and nonvertebral fractures were 35% and 38%, respectively. Strontium ranelate was safe and well tolerated over 10 years. Long-term treatment with strontium ranelate is associated with sustained increases in BMD over 10 years, with a good safety profile. Our results also support the maintenance of antifracture efficacy over 10 years with strontium ranelate.

  3. Impact of reduced ignition propensity cigarette regulation on consumer smoking behavior and quit intentions: evidence from 6 waves (2004–11) of the ITC Four Country Survey

    Science.gov (United States)

    2013-01-01

    Background Although on the decline, smoking-related fires remain a leading cause of fire death in the United States and United Kingdom and account for over 10% of fire-related deaths worldwide. This has prompted lawmakers to enact legislation requiring manufacturers to implement reduced ignition propensity (RIP) safety standards for cigarettes. The current research evaluates how implementation of RIP safety standards in different countries influenced smokers’ perceptions of cigarette self-extinguishment, frequency of extinguishment, and the impact on consumer smoking behaviors, including cigarettes smoked per day and planning to quit. Methods Participants for this research come from Waves 3 through 8 of the International Tobacco Control (ITC) Four Country Survey conducted longitudinally from 2004 through 2011 in the United States, United Kingdom, Australia, and Canada. Results Perceptions of cigarette self-extinguishment and frequency of extinguishment increased concurrently with an increase in the prevalence of RIP safety standards for cigarettes. Presence of RIP safety standards was also associated with a greater intention to quit smoking, but was not associated with the number of cigarettes smoked per day. Intention to quit was higher among those who were more likely to report that their cigarettes self-extinguish sometimes and often, but we found no evidence of an interaction between frequency of extinguishment and RIP safety standards on quit intentions. Conclusions Overall, because these standards largely do not influence consumer smoking behavior, RIP implementation may significantly reduce the number of cigarette-related fires and the associated death and damages. Further research should assess how implementation of RIP safety standards has influenced smoking-related fire incidence, deaths, and other costs associated with smoking-related fires. PMID:24359292

  4. Impact of reduced ignition propensity cigarette regulation on consumer smoking behavior and quit intentions: evidence from 6 waves (2004-11) of the ITC Four Country Survey.

    Science.gov (United States)

    Adkison, Sarah E; O'Connor, Richard J; Borland, Ron; Yong, Hua-Hie; Cummings, K Michael; Hammond, David; Fong, Geoffrey T

    2013-12-21

    Although on the decline, smoking-related fires remain a leading cause of fire death in the United States and United Kingdom and account for over 10% of fire-related deaths worldwide. This has prompted lawmakers to enact legislation requiring manufacturers to implement reduced ignition propensity (RIP) safety standards for cigarettes. The current research evaluates how implementation of RIP safety standards in different countries influenced smokers' perceptions of cigarette self-extinguishment, frequency of extinguishment, and the impact on consumer smoking behaviors, including cigarettes smoked per day and planning to quit. Participants for this research come from Waves 3 through 8 of the International Tobacco Control (ITC) Four Country Survey conducted longitudinally from 2004 through 2011 in the United States, United Kingdom, Australia, and Canada. Perceptions of cigarette self-extinguishment and frequency of extinguishment increased concurrently with an increase in the prevalence of RIP safety standards for cigarettes. Presence of RIP safety standards was also associated with a greater intention to quit smoking, but was not associated with the number of cigarettes smoked per day. Intention to quit was higher among those who were more likely to report that their cigarettes self-extinguish sometimes and often, but we found no evidence of an interaction between frequency of extinguishment and RIP safety standards on quit intentions. Overall, because these standards largely do not influence consumer smoking behavior, RIP implementation may significantly reduce the number of cigarette-related fires and the associated death and damages. Further research should assess how implementation of RIP safety standards has influenced smoking-related fire incidence, deaths, and other costs associated with smoking-related fires.

  5. Natural History of Thyroid Function in Adults with Down Syndrome--10-Year Follow-Up Study

    Science.gov (United States)

    Prasher, V.; Gomez, G.

    2007-01-01

    Background: The natural history of thyroid function in adults with Down syndrome (DS) is unknown. Method: This study investigated annual thyroid function tests in 200 adults with DS over a 10-year period. Results: Transient and persistent thyroid dysfunction was common. The 5- and 10-year incidence of definite hypothyroidism was 0.9%-1.64% and…

  6. Self-Esteem during University Studies Predicts Career Characteristics 10 Years Later

    Science.gov (United States)

    Salmela-Aro, Katariina; Nurmi, Jari-Erik

    2007-01-01

    To examine how self-esteem measured during university studies would impact on the characteristics of the work career 10 years later, 297 university students completed the Rosenberg's self-esteem inventory four times while at university and various career-related questionnaires 10 years later. Latent Growth Curve Modeling showed that a high overall…

  7. Monitoring the Affordability of Healthy Eating: A Case Study of 10 Years of the Illawarra Healthy Food Basket

    Directory of Open Access Journals (Sweden)

    Peter Williams

    2010-11-01

    Full Text Available Healthy food baskets have been used around the world for a variety of purposes, including: examining the difference in cost between healthy and unhealthy food; mapping the availability of healthy foods in different locations; calculating the minimum cost of an adequate diet for social policy planning; developing educational material on low cost eating and examining trends on food costs over time. In Australia, the Illawarra Healthy Food Basket was developed in 2000 to monitor trends in the affordability of healthy food compared to average weekly wages and social welfare benefits for the unemployed. It consists of 57 items selected to meet the nutritional requirements of a reference family of five. Bi-annual costing from 2000–2009 has shown that the basket costs have increased by 38.4% in the 10-year period, but that affordability has remained relatively constant at around 30% of average household incomes.

  8. Association of depression and anxiety status with 10-year cardiovascular disease incidence among apparently healthy Greek adults: The ATTICA Study.

    Science.gov (United States)

    Kyrou, Ioannis; Kollia, Natasa; Panagiotakos, Demosthenes; Georgousopoulou, Ekavi; Chrysohoou, Christina; Tsigos, Constantine; Randeva, Harpal S; Yannakoulia, Mary; Stefanadis, Christodoulos; Papageorgiou, Charalabos; Pitsavos, Christos

    2017-01-01

    Background Chronic stress frequently manifests with anxiety and/or depressive symptomatology and may have detrimental cardiometabolic effects over time. As such, recognising the potential links between stress-related psychological disorders and cardiovascular disease (CVD) is becoming increasingly important in cardiovascular epidemiology research. The primary aim of this study was to explore prospectively potential associations between clinically relevant depressive symptomatology and anxiety levels and the 10-year CVD incidence among apparently healthy Greek adults. Design A population-based, health and nutrition prospective survey. Methods In the context of the ATTICA Study (2002-2012), 853 adult participants without previous CVD history (453 men (45 ± 13 years) and 400 women (44 ± 18 years)) underwent psychological evaluations through validated, self-reporting depression and anxiety questionnaires. Results After adjustment for multiple established CVD risk factors, both reported depression and anxiety levels were positively and independently associated with the 10-year CVD incidence, with depression markedly increasing the CVD risk by approximately fourfold (adjusted odds ratio (95% confidence interval) 3.6 (1.3, 11) for depression status; 1.03 (1.0, 1.1) for anxiety levels). Conclusions Our findings indicate that standardised psychological assessments focusing on depression and anxiety should be considered as an additional and distinct aspect in the context of CVD preventive strategies that are designed and implemented by health authorities at the general population level.

  9. The feasibility of measuring and monitoring social determinants of health and the relevance for policy and programme – a qualitative assessment of four countries

    Directory of Open Access Journals (Sweden)

    Erik Blas

    2016-02-01

    Full Text Available Background: Since the publication of the reports by the Commission on Social Determinants of Health (CSDH, many research papers have documented inequities, explaining causal pathways in order to inform policy and programmatic decision-making. At the international level, the sustainable development goals (SDGs reflect an attempt to bring together these themes and the complexities involved in defining a comprehensive development framework. However, to date, much less has been done to address the monitoring challenges, that is, how data generation, analysis and use are to become routine tasks. Objective: To test proposed indicators of social determinants of health (SDH, gender, equity, and human rights with respect to their relevance in tracking progress in universal health coverage and population health (level and distribution. Design: In an attempt to explore these monitoring challenges, indicators covering a wide range of social determinants were tested in four country case studies (Bangladesh, Brazil, South Africa, and Vietnam for their technical feasibility, reliability, and validity, and their communicability and usefulness to policy-makers. Twelve thematic domains with 20 core indicators covering different aspects of equity, human rights, gender, and SDH were tested through a review of data sources, descriptive analyses, key informant interviews, and focus group discussions. To test the communicability and usefulness of the domains, domain narratives that explained the causal pathways were presented to policy-makers, managers, the media, and civil society leaders. Results: For most countries, monitoring is possible, as some data were available for most of the core indicators. However, a qualitative assessment showed that technical feasibility, reliability, and validity varied across indicators and countries. Producing understandable and useful information proved challenging, and particularly so in translating indicator definitions and data

  10. Public awareness of aesthetic and other forest values associated with sustainable forest management: a cross-cultural comparison among the public in four countries.

    Science.gov (United States)

    Lim, Sang Seop; Innes, John L; Meitner, Michael

    2015-03-01

    Korea, China, Japan and Canada are all members of the Montreal Process (MP). However, there has been little comparative research on the public awareness of forest values within the framework of Sustainable Forest Management, not only between Asia and Canada, but also among these three Asian countries. This is true of aesthetic values, especially as the MP framework has no indicator for aesthetic values. We conducted surveys to identify similarities and differences in the perceptions of various forest values, including aesthetic values, between residents of the four countries: university student groups in Korea, China, Japan and Canada, as well as a more detailed assessment of the attitudes of Koreans by including two additional groups, Korean office workers, and Koreans living in Canada. A multivariate analysis of variance test across the four university student groups revealed significant differences in the rating of six forest functions out of 31. However the same test across the three Korean groups indicated no significant differences indicating higher confidence in the generalizability of our university student comparisons. For the forest aesthetic values, an analysis of variance test showed no significant differences across all groups. The forest aesthetic value was rated 6.95 to 7.98 (out of 10.0) depending on the group and rated relatively highly among ten social values across all the groups. Thurstone scale rankings and relative distances of six major forest values indicated that climate change control was ranked as the highest priority and scenic beauty was ranked the lowest by all the groups. Comparison tests of the frequencies of preferred major forest values revealed no significant differences across the groups with the exception of the Japanese group. These results suggest that public awareness of aesthetic and other forest values are not clearly correlated with the cultural backgrounds of the individuals, and the Korean university students' awareness

  11. Prevalence and sociodemographic determinants of tobacco use in four countries of the World Health Organization: South-East Asia region: Findings from the Global Adult Tobacco Survey

    Directory of Open Access Journals (Sweden)

    K Palipudi

    2014-01-01

    Full Text Available Introduction: Tobacco use is a leading cause of deaths and Disability Adjusted Life Years lost worldwide, particularly in South-East Asia. Health risks associated with exclusive use of one form of tobacco alone has a different health risk profile when compared to dual use. In order to tease out specific profiles of mutually exclusive categories of tobacco use, we carried out this analysis. Methods: The Global Adult Tobacco Survey (GATS data was used to describe the profiles of three mutually exclusive tobacco use categories ("Current smoking only," "Current smokeless tobacco [SLT] use only," and "Dual use" in four World Health Organization South-East Asia Region countries, namely Bangladesh, India, Indonesia and Thailand. GATS was a nationally representative household-based survey that used a stratified multistage cluster sampling design proportional to population size. Prevalence of different forms of usage were described as proportions. Logistics regression analyses was performed to calculate odds ratios (OR with 95% confidence intervals. All analyses were weighted, accounted for the complex sampling design and conducted using SPSS version 18. Results: The prevalence of different forms of tobacco use varied across countries. Current tobacco use ranged from 27.2% in Thailand to 43.3% in Bangladesh. Exclusively smoking was more common in Indonesia (34.0% and Thailand (23.4% and less common in Bangladesh (16.1% and India (8.7%. Exclusively using SLT was more common in Bangladesh (20.3% and India (20.6% and less common on Indonesia (0.9% and Thailand (3.5%. Dual use of smoking and SLT was found in Bangladesh (6.8% and India (5.3%, but was negligible in Indonesia (0.8 and Thailand (0.4%. Gender, age, education and wealth had significant effects on the OR for most forms of tobacco use across all four countries with the exceptions of SLT use in Indonesia and dual use in both Indonesia and Thailand. In general, the different forms of tobacco use

  12. Actual over 10-year survival after liver resection for patients with intrahepatic cholangiocarcinoma.

    Science.gov (United States)

    Si, Anfeng; Li, Jun; Xiang, Hongjun; Zhang, Shichao; Bai, Shilei; Yang, Pinghua; Zhang, Xiaofeng; Xia, Yong; Wang, Kui; Yan, Zhenlin; Lau, Wan Yee; Shi, Lehua; Shen, Feng

    2017-07-04

    Partial hepatectomy is a potentially curative therapy for intrahepatic cholangiocarcinoma (ICC). Unfortunately, the overall surgical prognosis remains dismal and the actual 10-year survival has not been reported. This study aimed to document 10-year actual survival rates, identify the prognostic factors associated with 10-year survival rate, and analyze the characteristics of patients who survived ≥ 10 years. Among 251 patients who underwent curative liver resection for ICC between 2003 and 2006 at the Eastern Hepatobiliary Surgery Hospital, 21 patients (8.4%) survived ≥ 10 years. The 5-, 7-, and 10-year overall survival rates were 32.3%, 22.3% and 8.4%, respectively. The 10-year cumulative incidence of ICC-related death and recurrence were 80.9% and 85.7%, respectively. Multivariate analysis based on competing risk survival analysis identified that tumor > 5 cm was independently associated with ICC-related death and recurrence (hazard ratios: 1.369 and 1.445, respectively), in addition to carcinoembryonic antigen (CEA) >10 U/mL, carbohydrate antigen 19-9 (CA19-9) >39 U/mL, multiple nodules, vascular invasion, nodal metastasis and local extrahepatic invasion. Patients who survived ≥ 10 years had a longer time to first recurrence, lower levels of CEA, CA19-9 and alkaline phosphatase, less perioperative blood loss, solitary tumor, smaller tumor size, and absence of nodal metastasis or local extrahepatic invasion. In conclusion, a 10-year survival after liver resection for ICC is possible and can be expected in approximately 8.4% of patients.

  13. Treating severe partial anodontia: a 10-year history of patient treatment.

    Science.gov (United States)

    Dario, L J; Aschaffenburg, P H

    1994-12-01

    Severe partial anodontia is relatively rare. This case report describes the 10-year treatment history of a patient with partial anodontia, beginning with removable partial overlay dentures and culminating with fixed implant prostheses.

  14. Implant-retained mandibular overdentures versus conventional dentures : 10 years of care and aftercare

    NARCIS (Netherlands)

    Visser, A; Meijer, HJA; Raghoebar, GM; Vissink, A

    2006-01-01

    Purpose: This 10-year prospective, randomized, clinical trial investigated the treatment outcome of edentulous patients treated with mandibular overdentures retained by 2 endosseous implants compared with conventional dentures in patients with or without vestibuloplasty. Materials and Methods: One

  15. Complications in Neck Dissection 10 years ex-perience with 268 cases in the Cancer Institute

    Directory of Open Access Journals (Sweden)

    M.K. OSKOUI

    1973-07-01

    Full Text Available Immediate and late post operative complications or radical Neck Dissection were discussed. Preventive measures and the treatment of each were mentioned briefly. Our 10 years experience with complications or neck dissection in the Cancer Institute was presented.

  16. The 10-Year Cost-Effectiveness of Lifestyle Intervention or Metformin for Diabetes Prevention

    OpenAIRE

    ,

    2012-01-01

    OBJECTIVE The Diabetes Prevention Program (DPP) and its Outcomes Study (DPPOS) demonstrated that either intensive lifestyle intervention or metformin could prevent type 2 diabetes in high-risk adults for at least 10 years after randomization. We report the 10-year within-trial cost-effectiveness of the interventions. RESEARCH DESIGN AND METHODS Data on resource utilization, cost, and quality of life were collected prospectively. Economic analyses were performed from health system and societal...

  17. Formation and Development of Diabatic Rossby Vortices in a 10-Year Climatology

    Science.gov (United States)

    2012-06-01

    DEVELOPMENT OF DIABATIC ROSSBY VORTICES IN A 10-YEAR CLIMATOLOGY by Nengwei “Tom” Shih June 2012 Thesis Advisor: Richard W. Moore Second...TYPE AND DATES COVERED Master’s Thesis 4. TITLE AND SUBTITLE Formation and Development of Diabatic Rossby Vortices in a 10-Year Climatology 5...release; distribution is unlimited 12b. DISTRIBUTION CODE A 13. ABSTRACT (maximum 200 words) A diabatic Rossby vortex (DRV) is a short-scale

  18. Nutrition and mortality in the elderly over 10 years of follow-up: the Three-City study.

    Science.gov (United States)

    Letois, Flavie; Mura, Thibault; Scali, Jacqueline; Gutierrez, Laure-Anne; Féart, Catherine; Berr, Claudine

    2016-09-01

    In the last 20 years, many prospective cohort studies have assessed the relationships between food consumption and mortality. Result interpretation is mainly hindered by the limited adjustment for confounders and, to a lesser extent, the small sample sizes. The aim of this study was to investigate the association between dietary habits and all-cause mortality in a multicentre prospective cohort that included non-institutionalised, community-based elderly individuals (Three-City Study). A brief FFQ was administered at baseline. Hazard ratios (HR) and 95 % CI for all-cause mortality were estimated relative to the consumption frequency of several food groups, using Cox proportional hazards models adjusted for sex, centre, socio-demographic characteristics and health status indicators. Among the 8937 participants (mean age: 74·2 years, 60·7 % women), 2016 deaths were recorded during an average follow-up of 9 years. The risk of death was significantly lower among subjects with the highest fruit and vegetable consumption (HR 0·90; 95 % CI 0·82, 0·99, P=0·03) and with regular fish consumption (HR 0·89; 95 % CI 0·81, 0·97, P=0·01). The benefit of olive oil use was found only in women (moderate olive oil use: HR 0·80; 95 % CI 0·68, 0·94, P=0·007; intensive use: HR 0·72; 95 % CI 0·60, 0·85, P=0·0002). Conversely, daily meat consumption increased the mortality risk (HR 1·12; 95 % CI, 1·01, 1·24, P=0·03). No association was found between risk of death and diet diversity and use of various fats. These findings suggest that fruits/vegetables, olive oil and regular fish consumptions have a beneficial effect on the risk of death, independently of the socio-demographic features and the number of medical conditions.

  19. [Treatment of chronic refractory idiopathic thrombocytopenia purpura. 10 years experience at the Salvador Zubiran National Institute of Nutrition].

    Science.gov (United States)

    Pita-Ramírez, L; Hurtado-Monroy, R; Labardini-Méndez, J

    1992-01-01

    A total of 126 patients with chronic idiopathic thrombocytopenic purpura were diagnosed from January 1980 to January 1990 in our institute. In this group of patients, 21 were refractory to prednisone therapy, splenectomy or both, or had had a relapse after a good response with these treatments. They were given other therapies. There was enough information for evaluation in 16 of the 21 patients. The treatment responses were classified according to the post-therapy platelet counts: complete response (CR) = > 150 x 10(9)/L for more than three months; partial response (PR) = 50-150 x 10(9)/L for more than three months; any response (AR) = CR + PR; no response (NR) = < 50 x 10(9)/L. There were 15 women and one male. The median age was 41 years (range 11 to 65). 6-mercaptopurine was given in all patients with CR = 31.2%, PR = 18.8%, AR = 50% and NR = 50%. Seven patients received cyclophosphamide with CR = 28.6%, PR = 14.3%, AR = 42.9% and NR = 57%. Vincristine was given in four patients with only one PR. Interferon alpha 2B was given in four patients with two transitory PR. One patient received colchicine and vitamin C without response. It is concluded that 6-mercaptopurine and cyclophosphamide are useful drugs in refractory thrombocytopenic purpura.

  20. Dental age estimation: the role of probability estimates at the 10 year threshold.

    Science.gov (United States)

    Lucas, Victoria S; McDonald, Fraser; Neil, Monica; Roberts, Graham

    2014-08-01

    The use of probability at the 18 year threshold has simplified the reporting of dental age estimates for emerging adults. The availability of simple to use widely available software has enabled the development of the probability threshold for individual teeth in growing children. Tooth development stage data from a previous study at the 10 year threshold were reused to estimate the probability of developing teeth being above or below the 10 year thresh-hold using the NORMDIST Function in Microsoft Excel. The probabilities within an individual subject are averaged to give a single probability that a subject is above or below 10 years old. To test the validity of this approach dental panoramic radiographs of 50 female and 50 male children within 2 years of the chronological age were assessed with the chronological age masked. Once the whole validation set of 100 radiographs had been assessed the masking was removed and the chronological age and dental age compared. The dental age was compared with chronological age to determine whether the dental age correctly or incorrectly identified a validation subject as above or below the 10 year threshold. The probability estimates correctly identified children as above or below on 94% of occasions. Only 2% of the validation group with a chronological age of less than 10 years were assigned to the over 10 year group. This study indicates the very high accuracy of assignment at the 10 year threshold. Further work at other legally important age thresholds is needed to explore the value of this approach to the technique of age estimation. Copyright © 2014. Published by Elsevier Ltd.

  1. Sex differences in cognition are stable over a 10-year period in adulthood and old age.

    Science.gov (United States)

    de Frias, Cindy M; Nilsson, Lars-Göran; Herlitz, Agneta

    2006-01-01

    Sex differences in declarative memory and visuospatial ability are robust in cross-sectional studies. The present longitudinal study examined whether sex differences in cognition were present over a 10-year period, and whether age modified the magnitude of sex differences. Tests assessing episodic and semantic memory, and visuospatial ability were administered to 625 nondemented adults (initially aged 35-80 years), participating in the population-based Betula study at two follow-up occasions. There was stability of sex differences across five age groups and over a 10-year period. Women performed at a higher level than men on episodic recall, face and verbal recognition, and semantic fluency, whereas men performed better than women on a task-assessing, visuospatial ability. Sex differences in cognitive functions are stable over a 10-year period and from 35 to 90 years of age.

  2. Visual plus nonvisual hallucinations in Parkinson's disease: development and evolution over 10 years.

    Science.gov (United States)

    Goetz, Christopher G; Stebbins, Glenn T; Ouyang, Bichun

    2011-10-01

    The objective of the study was to assess the development and evolution of visual and nonvisual hallucinations in patients with Parkinson's disease over 10 years. Hallucinations increase over time, but minimal attention has been placed on nonvisual domains. We studied 60 patients with Parkinson's disease who had never hallucinated at baseline and followed them over 10 years. The Rush Hallucination Inventory monitored frequency and type (visual, auditory, tactile, olfactory) of hallucinations at baseline and after 0.5, 1.5, 4, 6, and 10 years. Descriptive statistics were applied, and general estimating equation modeling assessed longitudinal risks. Over 10 years, visual hallucinations were endorsed by patients more frequently than other sensory modalities. Whereas isolated visual hallucinations dominated the early hallucination profile, visual plus nonvisual hallucinations accounted for progressively higher proportions of hallucinators over 10 years: 0.5 years, 0%; 4 years, 26%; 6 years, 47%; 10 years, 60% (odds ratio, 1.17; confidence interval, 1.01-1.37; P = .04). Once visual plus nonvisual hallucinations developed, the risk of continuing to have multidomain hallucinations was high (odds ratio, 3.67; confidence interval, 1.13-11.93; P = .03). Hallucination severity was highly associated with current visual plus nonvisual hallucinations (odds ratio, 4.06; confidence interval, 2.93-5.61; P hallucinations (odds ratio, 1.58; confidence interval, 1.12-2.24; P = .01). Whereas visual hallucinations in isolation are classic in Parkinson's disease, nonvisual hallucinations emerge over time, and the combination of visual with nonvisual hallucinations predominates in late Parkinson's disease. To capture the breadth and severity of hallucinations in chronically hallucinating patients with Parkinson's disease, screening inventories and practice-based interviews must include questions on both visual and nonvisual components.

  3. Depressive symptoms in first-episode psychosis: a 10-year follow-up study.

    Science.gov (United States)

    Sönmez, Nasrettin; Røssberg, Jan Ivar; Evensen, Julie; Barder, Helene Eidsmo; Haahr, Ulrik; Ten Velden Hegelstad, Wenche; Joa, Inge; Johannessen, Jan Olav; Langeveld, Hans; Larsen, Tor Ketil; Melle, Ingrid; Opjordsmoen, Stein; Rund, Bjørn Rishovd; Simonsen, Erik; Vaglum, Per; McGlashan, Thomas; Friis, Svein

    2016-06-01

    The present study examined if any patient characteristics at baseline predicted depressive symptoms at 10 years and whether patients prone to depressive symptoms in the first year of treatment had a different prognosis in the following years. A total of 299 first-episode psychosis (FEP) patients with schizophrenia spectrum disorders were assessed for depressive symptoms with PANSS depression item (g6) at baseline, and 1, 2, 5 and 10 years of follow up. At 10 years, depressive symptoms were also assessed with Calgary Depression Scale for Schizophrenia (CDSS). A PANSS g6 ≥ 4 and CDSS score ≥ 6 were used as a cut-off score for depression. A total of 122 (41%) patients were scored as depressed at baseline, 75 (28%) at 1 year, 50 (20%) at 2 years, 33 (16%) at 5 years, and 35 (19%) at 10 years of follow up. Poor childhood social functioning and alcohol use at baseline predicted depression at 10 years of follow up. Thirty-eight patients were depressed at both baseline and 1 year follow up. This group had poorer symptomatic and functional outcome in the follow-up period compared to a group of patients with no depression in the first year of treatment. Depressive symptoms are frequent among FEP patients at baseline but decrease after treatment because their general symptoms have been initiated. Patients with poor social functioning in childhood and alcohol use at baseline are more prone to have depressive symptoms at 10 years of follow up. Patients struggling with depressive symptoms in the first year of treatment should be identified as having poorer long-term prognosis. © 2014 Wiley Publishing Asia Pty Ltd.

  4. The Effects of Crowding on the Behavior and Perception of 10-Year-Old Boys

    Science.gov (United States)

    Loo, Chalsa; Smetana, Judi

    1978-01-01

    This study integrated observational and self-report methods to investigate the effects of low and high spatial density on 10-year-old boys in an experimental setting. Five factors emerged: discomfort and dislike of room; active play; avoidance; positive group interactions; and anger and aggression. (Author)

  5. Relationship between Motor Skill and Body Mass Index in 5- to 10-Year-Old Children

    Science.gov (United States)

    D'Hondt, Eva; Deforche, Benedicte; De Bourdeaudhuij, Ilse; Lenoir, Matthieu

    2009-01-01

    The purpose of this study was to investigate gross and fine motor skill in overweight and obese children compared with normal-weight peers. According to international cut-off points for Body Mass Index (BMI) from Cole et al. (2000), all 117 participants (5-10 year) were classified as being normal-weight, overweight, or obese. Level of motor skill…

  6. The impact factor of rheumatology journals : an analysis of 2008 and the recent 10 years

    NARCIS (Netherlands)

    Chen, Min; Zhao, Ming-Hui; Kallenberg, Cees G. M.

    2011-01-01

    Despite various weaknesses, the impact factor (IF) is still used as an important indictor for scientific quality in specific subject categories. In the current study, the IFs of rheumatology journals over the past 10 years were serially analyzed and compared with that from other fields. For the past

  7. Antipsychotic medication and remission of psychotic symptoms 10years after a first-episode psychosis

    DEFF Research Database (Denmark)

    Wils, Regitze Sølling; Gotfredsen, Ditte Resendal; Hjorthøj, Carsten

    2017-01-01

    spectrum disorders (ICD 10: F20 and F22-29). Patients were included in the Danish OPUS Trial and followed up 10years after inclusion, where patient data was collected on socio-demographic factors, psychopathology, level of functioning and medication. FINDINGS: 61% of the patients from the original cohort...

  8. Adolescent Drug Trafficking Trends in the United Kingdom--A 10-Year Retrospective Analysis

    Science.gov (United States)

    Vale, Ellen Louise Eva; Kennedy, Patrick John

    2004-01-01

    This paper reports data from HM Customs and Excise (HMCE) of recorded cases of adolescent drug trafficking through all sea and air points of entry into the UK over a 10-year period (May 1992-May 2002). We report the characteristics of 38 cases of mixed gender and nationality ranging in age between 13 and 18 years who have been apprehended by HMCE…

  9. Effect of meteorology and soil condition on metolachlor and atrazine volatilization over a 10 year period

    Science.gov (United States)

    Volatilization of pesticides can detrimentally affect the environment by contaminating soil and surface waters far away from where the pesticides were applied. A 10-year study was conducted to focus on the impact of soil and climatic factors governing herbicide volatilization from an agricultural f...

  10. The impact factor of rheumatology journals : an analysis of 2008 and the recent 10 years

    NARCIS (Netherlands)

    Chen, Min; Zhao, Ming-Hui; Kallenberg, Cees G. M.

    2011-01-01

    Despite various weaknesses, the impact factor (IF) is still used as an important indictor for scientific quality in specific subject categories. In the current study, the IFs of rheumatology journals over the past 10 years were serially analyzed and compared with that from other fields. For the past

  11. A Content Analysis of 10 Years of Clinical Supervision Articles in Counseling

    Science.gov (United States)

    Bernard, Janine M.; Luke, Melissa

    2015-01-01

    This content analysis follows Borders's (2005) review of counseling supervision literature and includes 184 counselor supervision articles published over the past 10 years. Articles were coded as representing 1 of 3 research types or 1 of 3 conceptual types. Articles were then analyzed for main topics producing 11 topic categories.

  12. 10 Years of "Adult Learning": Content Analysis of an Academic Journal

    Science.gov (United States)

    Cherrstrom, Catherine A.; Robbins, Stacey E.; Bixby, John

    2017-01-01

    Academic publications provide insights into a discipline's history, knowledge base, and research norms, and thus analyzing publication activity provides learning about the field of study. To learn more about the field of adult and continuing education, this study used content analysis to examine 10 years of "Adult Learning" from 2006…

  13. Subsequent fracture rates in a nationwide population-based cohort study with a 10-year perspective

    DEFF Research Database (Denmark)

    Hansen, Louise; Petersen, Karin Dam; Eriksen, Stine Aistrup;

    2015-01-01

    Summary: Fractures after the age of 50 are frequently observed in Denmark, and many of these may be osteoporotic. This study examined the incidence of all and subsequent fractures in a 10-year period from 2001 to 2011. The incidence of subsequent fractures was high, especially following hip fract...

  14. Regular aquatic exercise for chronic kidney disease patients: a 10-year follow-up study.

    Science.gov (United States)

    Pechter, Ülle; Raag, Mait; Ots-Rosenberg, Mai

    2014-09-01

    Chronic kidney disease (CKD) patients not yet in dialysis can benefit from increased physical activity; however, the safety and outcomes of aquatic exercise have not been investigated in observational studies. The aim of this study was to analyze association of 10 years of regularly performed aquatic exercise with the study endpoint--that is, all-cause death or start of dialysis. Consecutive CKD patients were included in the study in January 2002. The exercise group (n=7) exercised regularly under the supervision of physiotherapist for 10 years; the control group (n=9), matched in terms of age and clinical parameters, remained sedentary. Low-intensity aerobic aquatic exercise was performed regularly twice a week; 32 weeks or more of exercise therapy sessions were conducted annually. None of the members of the aquatic exercise group reached dialysis or died in 10 years. In the sedentary control group, 55% reached the study endpoint--renal replacement therapy (n=2) or all-cause death (n=3). Occurrence of the study endpoint, compared using the exact multinomial test with unconditional margins, was statistically significantly different (P-value: 0.037) between the study groups. Regular supervised aquatic exercise arrested CKD progression. There was a statistically significant difference between the sedentary group and the exercise group in reaching renal replacement therapy or all-cause death in a follow-up time of 10 years.

  15. Monitoring levels of preservative sensitivity in Europe. A 10-year overview (1991-2000)

    DEFF Research Database (Denmark)

    Wilkinson, J D; Shaw, S; Andersen, Klaus Ejner

    2002-01-01

    A 10-year multicentre analysis of the frequency of sensitivity to common preservatives collected in 16 centres in 11 countries has shown stable but persisting high levels of sensitivity to formaldehyde and 5-chloro-2-methyl-4-isothiazolin-3-one + 2-methyl-4-isothiazolin-3-one (MCI/MI). It has als...

  16. Learning Benefits of Self-Controlled Knowledge of Results in 10-Year-Old Children

    Science.gov (United States)

    Chiviacowsky, Suzete; Wulf, Gabriele; Laroque de Medeiros, Franklin; Kaefer, Angelica; Tani, Go

    2008-01-01

    The purpose of the present study was to examine whether the learning benefits of self-controlled knowledge of results (KR) would generalize to children. Specifically, the authors chose 10-year-old children representative of late childhood. The authors used a task that required the children to toss beanbags at a target. One group received KR…

  17. Self-Controlled Feedback in 10-Year-Old Children: Higher Feedback Frequencies Enhance Learning

    Science.gov (United States)

    Chiviacowsky, Suzete; Wulf, Gabriele; de Medeiros, Franklin Laroque; Kaefer, Angelica; Wally, Raquel

    2008-01-01

    The purpose of the present study was to examine whether learning in 10-year-old children--that is, the age group for which the Chiviacowsky et al. (2006) study found benefits of self-controlled knowledge of results (KR)--would differ depending on the frequency of feedback they chose. The authors surmised that a relatively high feedback frequency…

  18. Progress in Global Surveillance and Response Capacity 10 Years After Severe Acute Respiratory Syndrome

    Centers for Disease Control (CDC) Podcasts

    2013-04-10

    Dr. Mike Miller reads an abridged version of the Emerging Infectious Diseases' synopsis, Progress in Global Surveillance and Response Capacity 10 Years after Severe Acute Respiratory Syndrome.  Created: 4/10/2013 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 4/11/2013.

  19. United States Transportation Command: 10 Years of Excellence, 1987-1997

    Science.gov (United States)

    1997-01-01

    Military Sealift Command-chartered vessel at the port of Mogadishu, Somalia. 18 10 YEARS OF EXCELLENCE 1993 Acting Secretary of Defense Donald J. Atwood ...thanks are extended to James K. Matthews, Ph.D., and Margaret �Peg� Nigra for their help in the preparation of this book. Citations: In addition to

  20. Bullying and Attention-Deficit-Hyperactivity Disorder in 10-Year-Olds in a Swedish Community

    Science.gov (United States)

    Holmberg, Kirsten; Hjern, Anders

    2008-01-01

    The association of attention-deficit-hyperactivity disorder (ADHD) with bullying in the peer group in school was studied in an entire population of 577 fourth graders (10-year-olds) in one municipality in Stockholm, Sweden. The schoolchildren were screened for ADHD in a two-step procedure that included Conners' ratings of behavioural problems:…

  1. Modelling the survivorship of Nigeria children in their first 10 years of ...

    African Journals Online (AJOL)

    Modelling the survivorship of Nigeria children in their first 10 years of life. ... social demographic and environmental characteristics to differentials in children ... years and predicted survivals for 6th to 10th years of life using life table techniques ...

  2. Somatic health of 2500 women examined at a sexual assault center over 10 years

    DEFF Research Database (Denmark)

    Larsen, Mie-Louise; Hilden, Malene; Skovlund, Charlotte W

    2016-01-01

    significantly after sexual assault. Likewise, the number of visits to a general practitioner was significantly higher in exposed women both before and after the assault (16 vs. 10/year). Complications associated with childbirth were not statistically different between the groups. CONCLUSIONS: Our results...

  3. Discontinuation of long-term benzodiazepine use : 10-year follow-up

    NARCIS (Netherlands)

    de Gier, N. A. H.; Gorgels, W. J. M. J.; Lucassen, P. L. B. J.; Voshaar, R. Oude; Mulder, J.; Zitman, F.

    2011-01-01

    Background. Several interventions aiming at discontinuation of long-term benzodiazepine use have been proven effective in the short term. However, data on the persistence of discontinuation are lacking. Objectives. To assess 10-year follow-up status in patients who succeeded in stopping benzodiazepi

  4. Comparing 9 to 10 Years Old Children's Performance in Tennis and Physical Fitness Activities

    Science.gov (United States)

    Olcucu, Burcin

    2013-01-01

    The aim of the study is to determine the degree of performance-related physical coordination of elementary education children (male and female) that play tennis according to their age and gender and to investigate the relationship between their motor ability tests and performances. A total of 210 children tennis players (9 to 10 years; 105 males…

  5. Impact of Adolescent Alcohol and Drug Use on Neuropsychological Functioning in Young Adulthood: 10-Year Outcomes

    Science.gov (United States)

    Hanson, Karen L.; Medina, Krista Lisdahl; Padula, Claudia B.; Tapert, Susan F.; Brown, Sandra A.

    2011-01-01

    Because of ongoing neuromaturation, youth with chronic alcohol/substance use disorders (AUD/SUD) are at risk for cognitive decrements during young adulthood. We prospectively examined cognition over 10 years based on AUD/SUD history. Youth (N = 51) with no AUD/SUD history (n = 14), persisting AUD/SUD (n = 18), or remitted AUD/SUD (n = 19) were…

  6. Parent-Child Relations and Adolescent Self-Image Following Divorce: A 10-Year Study.

    Science.gov (United States)

    Dunlop, Rosemary; Burns, Ailsa; Bermingham, Suzanne

    2001-01-01

    Explored links between self-image, family structure (divorced or intact), parent-child relations, and gender at 3 intervals over 10 years during adolescence to early adulthood. Results suggest a consistent relationship between high parental care, low overprotective control, and better self-image scores with a stronger effect among subjects from…

  7. Frontal Electroencephalogram Activation Asymmetry, Emotional Intelligence, and Externalizing Behaviors in 10-Year-Old Children

    Science.gov (United States)

    Santesso, L. Diane; Dana, L. Reker; Schmidt, Louis A.; Segalowitz, Sidney J.

    2006-01-01

    The purpose of the present study was to examine the relations among resting frontal brain electrical activity (EEG) (hypothesized to reflect a predisposition to positive versus negative affect and ability to regulate emotions), emotional intelligence, and externalizing behaviors in a sample of non-clinical 10-year-old children. We found that boys…

  8. A 10-year review of perioperative complications in pharyngeal flap surgery

    NARCIS (Netherlands)

    Hofer, SOP; Dhar, BK; Robinson, PH; Goorhuis-Brouwer, SM; Nicolai, JPA

    2002-01-01

    A 10-year retrospective study was undertaken to investigate perioperative complications in pharyngeal flap surgery in one institution using inferiorly and superiorly based flaps. In this fashion the current practice of surgical technique based on local findings and perioperative care, through regula

  9. Is the Party Over? Cannabis and Juvenile Psychiatric Disorder: The Past 10 Years

    Science.gov (United States)

    Rey, Joseph M.; Martin, Andres; Krabman, Peter

    2004-01-01

    Objective: To critically review cannabis research during the past 10 years in relation to rates of use, behavioral problems, and mental disorders in young people. Method: Studies published in English between 1994 and 2004 were identified through systematic searches of literature databases. The material was selectively reviewed focusing on child…

  10. Implant-retained mandibular overdentures versus conventional dentures: 10 years of care and aftercare.

    Science.gov (United States)

    Visser, Anita; Meijer, Henny J A; Raghoebar, Gerry M; Vissink, Arjan

    2006-01-01

    This 10-year prospective, randomized, clinical trial investigated the treatment outcome of edentulous patients treated with mandibular overdentures retained by 2 endosseous implants compared with conventional dentures in patients with or without vestibuloplasty. One hundred fifty-one edentulous patients (5 groups) with a symphyseal mandibular bone height between 8 and 25 mm participated. Sixty-two patients were treated with an overdenture retained by 2 implants (groups 1 and 3), 59 patients were treated with a conventional denture (groups 2 and 5), and 30 patients were treated with a conventional denture after preprosthetic vestibuloplasty (group 4). Patients who received conventional dentures but preferred implants later on could undergo implant surgery after 1 year of their initial treatment, but were analyzed in their original group. The prosthetic and surgical care and aftercare were scored during a 10-year evaluation period. One hundred thirty-three patients completed the 10-year follow-up evaluations. Forty-four percent of patients treated with conventional dentures switched within 10 years to implant-retained overdentures, versus 16% of the patients who were treated with conventional dentures after vestibuloplasty. On average, a greater time investment and more treatment sessions were needed in patients treated with implant-retained overdentures compared to patients treated with conventional dentures. Patients treated with an implant-retained overdenture need more treatment interventions and treatment time than patients treated with conventional dentures.

  11. Educational Attainment of 10-Year-Old Children with Treated and Untreated Visual Defects.

    Science.gov (United States)

    Stewart-Brown, Sarah; And Others

    1985-01-01

    Children with visual impairments who participated in a 10-year survey were compared with peers on measures of intelligence, reading, mathematics, and sporting ability. Results are consistent with earlier findings of increased intelligence among Ss with myopia and slightly reduced intelligence among Ss with amblyopia. It was concluded that the…

  12. Researching and Understanding Environmental Learning: Hopes for the Next 10 Years

    Science.gov (United States)

    Rickinson, Mark

    2006-01-01

    The tenth anniversary of "Environmental Education Research" comes at an interesting time. The next 10 years of the journal overlap with the United Nation's Decade for Education for Sustainable Development, with the possibilities that this may (or may not) bring for those working at the intersections of education and sustainable…

  13. Stress Generation, Avoidance Coping, and Depressive Symptoms: A 10-Year Model

    Science.gov (United States)

    Holahan, Charles J.; Moos, Rudolf H.; Holahan, Carole K.; Brennan, Penny L.; Schutte, Kathleen K.

    2005-01-01

    This study examined (a) the role of avoidance coping in prospectively generating both chronic and acute life stressors and (b) the stress-generating role of avoidance coping as a prospective link to future depressive symptoms. Participants were 1,211 late-middle-aged individuals (500 women and 711 men) assessed 3 times over a 10-year period. As…

  14. Psychiatric Aspects of Child and Adolescent Obesity: A Review of the Past 10 Years

    Science.gov (United States)

    Zametkin, Alan J.; Zoon, Christine K.; Klein, Hannah W.; Munson, Suzanne

    2004-01-01

    Objective: To review the past 10 years of published research on psychiatric aspects of child and adolescent obesity and highlight information mental health professionals need for preventing obesity in youths and diagnosing and treating it. Method: Researchers performed computerized and manual searches of the literature and summarized the most…

  15. A Content Analysis of 10 Years of Clinical Supervision Articles in Counseling

    Science.gov (United States)

    Bernard, Janine M.; Luke, Melissa

    2015-01-01

    This content analysis follows Borders's (2005) review of counseling supervision literature and includes 184 counselor supervision articles published over the past 10 years. Articles were coded as representing 1 of 3 research types or 1 of 3 conceptual types. Articles were then analyzed for main topics producing 11 topic categories.

  16. 10 Years of "Adult Learning": Content Analysis of an Academic Journal

    Science.gov (United States)

    Cherrstrom, Catherine A.; Robbins, Stacey E.; Bixby, John

    2017-01-01

    Academic publications provide insights into a discipline's history, knowledge base, and research norms, and thus analyzing publication activity provides learning about the field of study. To learn more about the field of adult and continuing education, this study used content analysis to examine 10 years of "Adult Learning" from 2006…

  17. Sex differences in stroke survival: 10-year follow-up of the Copenhagen stroke study cohort

    DEFF Research Database (Denmark)

    Andersen, Morten Nonboe; Andersen, Klaus Kaae; Kammersgaard, Lars Peter

    2005-01-01

    the Scandinavian Stroke Scale (0-58); computed tomography determined stroke type. A risk factor profile was obtained for all including ischemic heart disease, hypertension, diabetes mellitus, atrial fibrillation, previous stroke, smoking, and alcohol consumption. Date of death was obtained within a 10-year follow-up...

  18. Sex Differences in Stroke Survival: 10-Year Follow-up of the Copenhagen Stroke Study Cohort

    DEFF Research Database (Denmark)

    Andersen, Morten Nonboe; Andersen, Klaus Kaae; Kammersgaard, Lars Peter

    2005-01-01

    the Scandinavian Stroke Scale (0-58); computed tomography determined stroke type. A risk factor profile was obtained for all including ischemic heart disease, hypertension, diabetes mellitus, atrial fibrillation, previous stroke, smoking, and alcohol consumption. Date of death was obtained within a 10-year follow-up...

  19. Cervical involvement in SAPHO syndrome: imaging findings with a 10-year follow-up

    Energy Technology Data Exchange (ETDEWEB)

    Tohme-Noun, C.; Krainik, A.; Menu, Y. [Department of Radiology, Hopital Beaujon, AP HP, Universite Paris 7, Faculte de medecine Bichat-Beaujon, Paris (France); Feydy, A. [Department of Radiology, Hopital Beaujon, AP HP, Universite Paris 7, Faculte de medecine Bichat-Beaujon, Paris (France); Department of Radiology, Hopital Beaujon, 100 avenue du General Leclerc, 92118, Clichy (France); Belmatoug, N.; Fantin, B. [Department of Internal Medicine, Hopital Beaujon, AP HP, Universite Paris 7, Faculte de medecine Bichat-Beaujon, Paris (France)

    2003-02-01

    Osteoarticular manifestations of SAPHO syndrome include vertebral lesions, typically in the thoracic segment. Chronic inflammatory changes are well depicted by MRI. We report the imaging findings with a 10-year follow-up in a case of SAPHO syndrome with marked cervical lesions. (orig.)

  20. Vascular malformations: A review of 10 years' management in a university hospital

    NARCIS (Netherlands)

    Zwerver, J.; Rieu, P.N.M.A.; Koopman, R.J.J.; Spauwen, P.H.M.; Buskens, F.G.M.; Boetes, C.; Veth, R.P.H.; Van Oostrom, C.G.

    1996-01-01

    In order to gain insight into the management of patients with vascular malformations (VM) in the University Hospital Nijmegen in the past 10 years, 151 cases managed by different specialists were reviewed. To avoid the usual confusion in terminology, all recorded diagnoses were reclassified accordin

  1. Intellectual ability 10 years after traumatic brain injury in infancy and childhood: what predicts outcome?

    Science.gov (United States)

    Anderson, Vicki; Catroppa, Cathy; Godfrey, Celia; Rosenfeld, Jeffrey V

    2012-01-01

    The long-term consequences of child traumatic brain injury (TBI) are poorly understood, but there are indications of ongoing deterioration in skills with time since injury. This study investigated outcomes up to 10 years post-injury, to determine the influences of injury severity, injury age, and environment. The study design was prospective and longitudinal. Participants included consecutive admissions to the Royal Children's Hospital, Melbourne, Australia. Children sustaining TBI between 2 and 12 years of age (n=76) were recruited on admission and divided according to injury severity (mild, moderate, and severe) and injury age (2-7 years and 8-12 years). Cognitive abilities were evaluated using standard measures of intellectual function (IQ) acutely and at 12 months, 30 months, and 10 years post-injury. At 10 years, mean IQs for survivors fell within the low average to average range. There were no significant effects of injury severity, injury age, or time since injury. In contrast, elevated rates of impairment were identified in association with severe TBI (global deficits), and early injury (non-verbal deficits). Impairments in processing speed were related to injury severity and age at injury. Predictors of 10-year outcome included pre-injury and social factors, injury age, and family function. Child survivors of serious TBI are at elevated risk of cognitive impairment, with recovery continuing into the third year post-injury. However, between 30 months and 10 years post-insult, children appear to make appropriate developmental gains, contrary to the speculation that these children "grow into their deficits."

  2. Income-related inequalities in the prevalence of depression and suicidal behaviour: a 10-year trend following economic crisis.

    Science.gov (United States)

    Hong, Jihyung; Knapp, Martin; McGuire, Alistair

    2011-02-01

    The issue of health inequalities has steadily gained attention in South Korea, as income inequality widened and social polarization increased following the country's economic crisis in the late 1990s. While official figures indicate a general trend of worsening mental health, with rapidly rising rates of suicide and depression in particular, the extent of socio-economic inequality with respect to mental health problems has not been well elucidated. This study aimed to measure income-related inequalities in depression, suicidal ideation and suicide attempts in South Korea and to trace their changes over a 10-year period (1998-2007). The concentration index approach was employed to quantify the degree of income-related inequalities, using four waves of the Korea National Health and Nutrition Examination Survey data. The study found persistent pro-rich inequality in depression, suicidal ideation and suicide attempts over the past decade (i.e., individuals with higher incomes were less likely to have these conditions). The inequalities actually doubled over this period. These findings imply a need for expanded social protection policies for the less privileged in the population.

  3. Predictors of Per- and Polyfluoroalkyl Substance (PFAS) Plasma Concentrations in 6-10 Year Old American Children.

    Science.gov (United States)

    Harris, Maria H; Rifas-Shiman, Sheryl L; Calafat, Antonia M; Ye, Xiaoyun; Mora, Ana Maria; Webster, Thomas F; Oken, Emily; Sagiv, Sharon K

    2017-05-02

    Certain per- and polyfluoroalkyl substances (PFASs) are suspected developmental toxicants, but data on PFAS concentrations and exposure routes in children are limited. We measured plasma PFASs in children aged 6-10 years from the Boston-area Project Viva prebirth cohort, and used multivariable linear regression to estimate associations with sociodemographic, behavioral, and health-related factors, and maternal PFASs measured during pregnancy. PFAS concentrations in Project Viva children (sampled 2007-2010) were similar to concentrations among youth participants (aged 12-19 years) in the 2007-8 and 2009-10 National Health and Nutrition Examination Survey (NHANES); mean concentrations of most PFASs declined from 2007 to 2010 in Project Viva and NHANES. In mutually adjusted models, predictors of higher PFAS concentrations included older child age, lower adiposity, carpeting or a rug in the child's bedroom, higher maternal education, and higher neighborhood income. Concentrations of perfluorooctanesulfonate (PFOS), perfluorooctanoate (PFOA), perfluorohexanesulfonate (PFHxS), and 2-(N-methyl-perfluorooctane sulfonamido) acetate (Me-PFOSA-AcOH) were 26-36% lower in children of black mothers compared to children of white mothers and increased 12-21% per interquartile range increase in maternal pregnancy PFASs. Breastfeeding duration did not predict childhood PFAS concentrations in adjusted multivariable models. Together, the studied predictors explained the observed variability in PFAS concentrations to only a modest degree.

  4. Family meals: perceptions of benefits and challenges among parents of 8- to 10-year-old children.

    Science.gov (United States)

    Fulkerson, Jayne A; Story, Mary; Neumark-Sztainer, Dianne; Rydell, Sarah

    2008-04-01

    The study purpose was to examine parental perceptions of the mealtime environment in families with school-aged children and identify strategies to improve the dietary quality of meals. Cross-sectional surveys were completed by a convenience sample of 107 parents (86% mothers, 14% fathers) of 8- to 10-year-old children who were recruited from afterschool child care programs/elementary schools. SAS (version 9.1) was used to produce descriptive frequencies of parental reports of positive and negative perceptions of mealtime. Parents reported frequent family meals; however, they indicated that family dinners were eaten at full-service restaurants, purchased from fast-food establishments, or picked up as takeout foods at least weekly (47.0%, 28.3%, and 23.8%, respectively). Conflicts about food were problematic for some families (40.2% on at least some days), and appeared to be related to children's food pickiness. Parents reported many benefits of family meals, including time for conversation, feelings of togetherness, shared nutrition, and ceremony. Areas where parents desired change included assistance with meal planning, food preparation, and clean-up; spending more time at meals; assistance with children's food pickiness; new recipes and meal ideas; and decreasing conflict at mealtimes. Findings suggest that interventions to increase family meal frequency and promote healthful foods at mealtimes should address promoting food acceptance among children, sharing responsibilities among parents and children for meal planning and preparation, decreasing conflict at meals, and eating out healthfully.

  5. Stress Generation, Avoidance Coping, and Depressive Symptoms: A 10-Year Model

    Science.gov (United States)

    Holahan, Charles J.; Moos, Rudolf H.; Holahan, Carole K.; Brennan, Penny L.; Schutte, Kathleen K.

    2011-01-01

    This study examined (a) the role of avoidance coping in prospectively generating both chronic and acute life stressors and (b) the stress-generating role of avoidance coping as a prospective link to future depressive symptoms. Participants were 1,211 late-middle-aged individuals (500 women and 711 men) assessed 3 times over a 10-year period. As predicted, baseline avoidance coping was prospectively associated with both more chronic and more acute life stressors 4 years later. Furthermore, as predicted, these intervening life stressors linked baseline avoidance coping and depressive symptoms 10 years later, controlling for the influence of initial depressive symptoms. These findings broaden knowledge about the stress-generation process and elucidate a key mechanism through which avoidance coping is linked to depressive symptoms. PMID:16173853

  6. Physical aggression, compromised social support, and 10-year marital outcomes: Testing a relational spillover model.

    Science.gov (United States)

    Sullivan, Kieran T; Pasch, Lauri A; Lawrence, Erika; Bradbury, Thomas N

    2015-12-01

    The purpose of the present study was to test a relational spillover model of physical aggression whereby physical aggression affects marital outcomes due to its effects on how spouses ask for and provide support to one another. Newlywed couples (n = 172) reported levels of physical aggression over the past year and engaged in interactions designed to elicit social support; marital adjustment, and stability were assessed periodically over the first 10 years of marriage. Multilevel modeling revealed that negative support behavior mediated the relationship between physical aggression and 10-year marital adjustment levels whereas positive support behavior mediated the relationship between physical aggression and divorce status. These findings emphasize the need to look beyond conflict when explaining how aggression affects relationships and when working with couples with a history of physical aggression who are seeking to improve their relationships.

  7. The fate of titanium miniplates and screws used in maxillofacial surgery: a 10 year retrospective study.

    LENUS (Irish Health Repository)

    O'Connell, J

    2012-01-31

    The objective of this 10 year, retrospective study is to evaluate the indications for the removal of titanium miniplates following osteosynthesis in maxillofacial trauma and orthognathic surgery. All patients who had miniplates placed in a Regional Oral and Maxillofacial Department between January 1998 and October 2007 were included. The following variables were recorded: patient gender and age, number of plates inserted, indications for plate placement, location of plates, number and location of plates removed, indications for plate removal, time between insertion and removal, medical co-morbidities, and the follow-up period. During the 10 years of the study, 1247 titanium miniplates were placed in 535 patients. A total of 32 (3%) plates were removed from 30 patients. Superficial infection accounted for 41% of all plates removed. All complications were minor and most plates were removed within the first year of insertion. A low removal rate of 3% suggests that the routine removal of asymptomatic titanium miniplates is not indicated.

  8. Rugby injuries to the cervical spine and spinal cord: a 10-year review.

    Science.gov (United States)

    Scher, A T

    1998-01-01

    A 10-year review (1987-1996) of injuries sustained to the spine and spinal cord in rugby players with resultant paralysis has been undertaken. This article reviews that the incidence of serious rugby spine and spinal cord injuries in South Africa has increased over the 10-year period reviewed, despite stringent new rules instituted in an attempt to decrease the incidence of these injuries. The mechanisms of injury, as previously reported, remain the same as well as the phases of game responsible for injury of the tight scrum, tackle, rucks, and mauls. Two new observations are reported: the first is related to the occurrence of spinal cord concussion with transient paralysis, and the second is related to the increased incidence of osteoarthritis of the cervical spine in rugby players.

  9. Sunlight and the 10-year incidence of age-related maculopathy: the Beaver Dam Eye Study.

    Science.gov (United States)

    Tomany, Sandra C; Cruickshanks, Karen J; Klein, Ronald; Klein, Barbara E K; Knudtson, Michael D

    2004-05-01

    To examine the association of sunlight exposure and indicators of sun sensitivity with the 10-year incidence of age-related maculopathy (ARM). Population-based cohort study. We included persons aged 43 to 86 years at the baseline examination from 1988 to 1990, living in Beaver Dam, Wis, of whom 3684 persons underwent 5-year follow-up and 2764 underwent 10-year follow-up. Data on sun exposure and indicators of sun sensitivity were obtained from a standardized questionnaire administered at baseline and/or follow-up. We determined ARM status by grading stereoscopic color fundus photographs using the Wisconsin Age-Related Maculopathy Grading System. Incidence and progression of ARM. While controlling for age and sex, we found that participants exposed to the summer sun for more than 5 hours a day during their teens, in their 30s, and at the baseline examination were at a higher risk of developing increased retinal pigment (risk ratio [RR], 2.99; 95% confidence interval [CI], 1.18-7.60; P =.02) and early ARM (RR, 2.20; 95% CI, 1.02-4.73; P =.04) [corrected] by 10 years than those exposed less than 2 hours per day during the same periods. In participants reporting the highest summer sun exposure levels in their teens and 30s, the use of hats and sunglasses at least half the time during the same periods was associated with a decreased risk of developing soft indistinct drusen (RR, 0.55; 95% CI, 0.33-0.90; P =.02) and retinal pigment epithelial depigmentation (RR, 0.51; 95% CI, 0.29-0.91; P =.02). Participants who experienced more than 10 severe sunburns during their youth were more likely than those who experienced 1 or no burn to develop drusen with a 250-microm diameter or larger (RR, 2.52; 95% CI, 1.29-4.94 [corrected] P =.01) by the 10-year examination. No relationships were found between UV-B exposure, winter leisure time spent outdoors, skin sun sensitivity, or number of bad sunburns experienced by the time of the baseline examination and the 10-year incidence and

  10. Homeland Security Affairs Journal, Volume VII - 2011, 10 Years After: The 9/11 Essays

    OpenAIRE

    2011-01-01

    Homeland Security Affairs is the peer-reviewed online journal of the Naval Postgraduate School Center for Homeland Defense and Security (CHDS), providing a forum to propose and debate strategies, policies, and organizational arrangements to strengthen U.S. homeland security. The instructors, participants, alumni, and partners of CHDS represent the leading subject matter experts and practitioners in the field of homeland security. 10 Years After: the 9/11 Essays. Homeland Security Affairs (...

  11. Psychological Factors Predict Eating Disorder Onset and Maintenance at 10-year Follow-up

    OpenAIRE

    Holland, Lauren A.; Bodell, Lindsay P.; Keel, Pamela K.

    2013-01-01

    The present study sought to identify psychological factors that predict onset and maintenance of eating disorders. Secondary analyses were conducted using data from an epidemiological study of health and eating behaviors in men and women (N=1320; 72% female) to examine the prospective and independent influence of the Eating Disorder Inventory (EDI) Perfectionism, Interpersonal Distrust, and Maturity Fears subscales in predicting the onset and maintenance of eating disorders at 10-year follow-...

  12. A 10 Year Survey of Neonatal Kidney Mass in North-East of Iran (Khorasn)

    OpenAIRE

    Golam-Ali Mamouri; Hassan Boskabadi; Farhad Heydarian

    2007-01-01

    Objective: Although abdominal mass in neonates is not common, it is very critical to detect it promptly.  2/3 of neonatal abdominal masses belong to kidney. Correct diagnosis and immediate appropriate management can prevent morbidity and mortality. This study pays special attention to incidence, associated anomalies and mortality rate in those neonates who suffered from palpable kidney mass. Material & Methods: During a period of 10 years 48250 neonates were examined for abdominal mass  by ne...

  13. The Impact of 10 Years of War on Combat Casualty Care Research: A Citation Analysis

    Science.gov (United States)

    2012-01-01

    METHODS The Thompson Reuters Web of Science was queried in October 2011 for articles published between 2001 and 2011, the first 10 years of the current...within Web of Science , we limited the selected articles to those within the fol- lowing subject areas of highest relevance to combat casualty care...accessed using the Web of Science database to obtain information about the number of article citations. A final review of the top 50 most frequently

  14. Khayelitsha 2001 - 2011: 10 years of primary care HIV and TB programmes

    Directory of Open Access Journals (Sweden)

    Daniela Belen Garone

    2011-12-01

    Full Text Available Tuberculosis (TB and HIV care in Khayelitsha, and in South Africa as a whole, has overcome numerous obstacles in the past three decades. This article highlights what has been achieved in Khayelitsha, describes the key clinical programme and policy changes that have supported universal coverage for HIV and TB care over the last 10 years, and outlines the challenges for the next decade.

  15. The Future of Federated Search, or What Will the World Look like in 10 Years

    Science.gov (United States)

    Turner, Rich

    2009-01-01

    In this article, the author contends that in 10 years, federated search--or search of any kind for that matter--won't exist. He elaborates that the "function" of search will exist--but not in a context with which anyone is familiar today. So if "search" doesn't exist in 2018, how will people find the information that they need across vast volumes…

  16. The Future of Federated Search, or What Will the World Look like in 10 Years

    Science.gov (United States)

    Turner, Rich

    2009-01-01

    In this article, the author contends that in 10 years, federated search--or search of any kind for that matter--won't exist. He elaborates that the "function" of search will exist--but not in a context with which anyone is familiar today. So if "search" doesn't exist in 2018, how will people find the information that they need across vast volumes…

  17. Changes in Pulmonary Function Up to 10 Years After Locoregional Breast Irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Erven, Katrien, E-mail: Katrien.erven@uzleuven.be [Department of Radiotherapy, University Hospital Gasthuisberg, Leuven (Belgium); Weltens, Caroline [Department of Radiotherapy, University Hospital Gasthuisberg, Leuven (Belgium); Nackaerts, Kristiaan [Department of Pulmonology, University Hospital Gasthuisberg, Leuven (Belgium); Fieuws, Steffen [I-BioStat, Catholic University Leuven and Hasselt University, Leuven (Belgium); Decramer, Marc [Department of Pulmonology, University Hospital Gasthuisberg, Leuven (Belgium); Lievens, Yolande [Department of Radiotherapy, University Hospital Gasthuisberg, Leuven (Belgium)

    2012-02-01

    Purpose: To evaluate the long-term impact of locoregional breast radiotherapy (RT) on pulmonary function tests (PFTs). Methods and Materials: This study included 75 women who underwent postoperative locoregional breast RT. PFTs were performed before RT and 3, 6, and 12 months and 8 to 10 years after RT. By use of univariate and multivariate analyses, the impact of treatment- and patient-related factors on late changes in PFTs was evaluated. Results: During the first year after RT, all PFTs significantly worsened at 3 to 6 months after RT (p < 0.05). At 12 months, forced vital capacity (FVC), vital capacity (VC), and forced expiratory volume in 1 second (FEV{sub 1}) recovered almost to baseline values, whereas total lung capacity (TLC) and diffusion capacity of carbon monoxide (DL{sub CO}) recovered only slightly and were still found to be decreased compared with baseline (p < 0.05). At 8 to 10 years after RT, mean reductions in FEV{sub 1} of 4% (p = 0.03) and in VC, DL{sub CO}, and TLC of 5%, 9%, and 11% (all p < 0.0001), respectively, were observed compared with pre-RT values. On multivariate analysis, tamoxifen use negatively affected TLC at 8 to 10 years after RT (p = 0.033), whereas right-sided irradiation was associated with a late reduction in FEV{sub 1} (p = 0.027). For FEV{sub 1} and DL{sub CO}, an early decrease was predictive for a late decrease (p = 0.003 and p = 0.0009, respectively). Conclusions: The time course of PFT changes after locoregional RT for breast cancer follows a biphasic pattern. An early reduction in PFTs at 3 to 6 months with a partial recovery at 12 months after RT is followed by a late, more important PFT reduction up to 8 to 10 years after RT. Tamoxifen use may have an impact on this late decline in PFTs.

  18. Prevalence of neonatal hypothyroidism and phenylketonuria in Southern Thailand: A 10-year report

    OpenAIRE

    Yavamal Sutivijit; Arirat Banpavichit; Viroj Wiwanitkit

    2011-01-01

    Background: Congenital hypothyroidism and phenylketonuria, the two major problems of several metabolic errors are presently the focus of attention, in Thailand. These two conditions are assigned as diseases to be controlled under the National Public Health Policies of Thailand. Materials and Methods: Here, the authors summarize and report the 10-year study on the prevalence of neonatal hypothyroidism and phenylketonuria in Southern Thailand. Results: This report is good representative data fr...

  19. Pyridoxine-dependent seizures: 10-year follow-up of eight cases.

    Science.gov (United States)

    Koul, Roshan

    2009-01-01

    Eight children with pyridoxine-dependent seizures (PDS) were seen over a period of 10 years. Of those children, 6 are on regular follow-up. Four of the children were seen in one family. All the patients presented with refractory seizures, mainly neonatal status epilepticus. Though PDS is a rare condition, it must be considered in all cases with refractory seizures, particularly in children younger than 3 years. When confirming a diagnosis, oral pyridoxine is as effective as intravenous pyridoxine.

  20. Pyridoxine-dependent seizures: 10-year follow-up of eight cases

    OpenAIRE

    2009-01-01

    Eight children with pyridoxine-dependent seizures (PDS) were seen over a period of 10 years. Of those children, 6 are on regular follow-up. Four of the children were seen in one family. All the patients presented with refractory seizures, mainly neonatal status epilepticus. Though PDS is a rare condition, it must be considered in all cases with refractory seizures, particularly in childrens younger than 3 years. When confirming a diagnosis, oral pyridoxine is as effective as intravenous pyrid...

  1. Orbital complications secondary to acute sinusitis– A 10 years retrospective review

    OpenAIRE

    2015-01-01

    Abstract Introduction: Orbital complication may accompany acute sinusitis in all age, commonly preseptal or orbital cellulitis. Aim: To evaluate the clinical presentation, management, and outcome of orbital complications of sinusitis in patients treated at our institution. Methods: A case study of retrospective review of 10 patients with orbital complications secondary to acute sinusitis was conducted in our centre over a 10-years period. The clinical presentation, relevant investigations, m...

  2. Stress Generation, Avoidance Coping, and Depressive Symptoms: A 10-Year Model

    OpenAIRE

    Holahan, Charles J.; Moos, Rudolf H.; Holahan, Carole K.; Brennan, Penny L.; Schutte, Kathleen K.

    2005-01-01

    This study examined (a) the role of avoidance coping in prospectively generating both chronic and acute life stressors and (b) the stress-generating role of avoidance coping as a prospective link to future depressive symptoms. Participants were 1,211 late-middle-aged individuals (500 women and 711 men) assessed 3 times over a 10-year period. As predicted, baseline avoidance coping was prospectively associated with both more chronic and more acute life stressors 4 years later. Furthermore, as ...

  3. The protective role of family meals for youth obesity: 10-year longitudinal associations.

    Science.gov (United States)

    Berge, Jerica M; Wall, Melanie; Hsueh, Tsun-Fang; Fulkerson, Jayne A; Larson, Nicole; Neumark-Sztainer, Dianne

    2015-02-01

    To examine whether having family meals as an adolescent protects against becoming overweight or obese 10 years later as a young adult. Data from Project Eating and Activity in Teens -III, a longitudinal cohort study with emerging young adults, were used. At baseline (1998-1999), adolescents completed surveys in middle or high schools, and at 10-year follow-up (2008-2009) surveys were completed online or via mailed surveys. Young adult participants (n = 2117) were racially/ethnically and socioeconomically diverse (52% minority; 38% low income) between the ages of 19 and 31 years (mean age = 25.3; 55% female). Logistic regression was used to associate weight status at follow-up with family meal frequency 10 years earlier during adolescence, controlling and testing for interactions with demographic characteristics. All levels of baseline family meal frequency (ie, 1-2, 3-4, ≥5 family meals/wk) during adolescence were significantly associated with reduced odds of overweight or obesity 10 years later in young adulthood compared with never having family meals as an adolescent. Interactions by race indicated that family meals had a stronger protective effect for obesity in black vs white young adults. Family meals during adolescence were protective against the development of overweight and obesity in young adulthood. Professionals who work with adolescents and parents may want to strategize with them how to successfully carry out at least 1 to 2 family meals per week in order to protect adolescents from overweight or obesity in young adulthood. Copyright © 2015 Elsevier Inc. All rights reserved.

  4. One-Month to 10-Year Survival in the Copenhagen Stroke Study

    DEFF Research Database (Denmark)

    Andersen, Klaus Kaae; Olsen, Tom Skyhøj

    2011-01-01

    .0 years; 56% women; mean Scandinavian Stroke Scale [SSS], 38.0 ± 17.4). Evaluation included stroke severity (based on the SSS), computed tomography scan, and a cardiovascular risk profile. Using logistic regression models, we examined the relevance of the SSS on mortality at 1 month and 1, 5, and 10 years....... We analyzed the proportion of the variation explained by the models and bias of risk factors estimates with and without the SSS in the model. Mortality rate was 16.6% at 1 month, 31.5% at 1 year, 60.2% at 5 years, and 81.3% at 10 years. In models including the SSS, 22.4%, 20.9%, 32.8%, and 39.......5% of the variance was explained for the endpoints of 1 month, 1 year, 5 years, and 10 years, respectively. When SSS was left out of the model, the corresponding values were 6.9%, 13.3%, 29.0%, and 35.1%. Factors significantly associated with survival were SSS at 1 month; SSS, age, diabetes, and stroke type at 1...

  5. Structural model of in-group dynamic of 6-10 years old boys’ motor fitness

    Directory of Open Access Journals (Sweden)

    Ivashchenko O.V.

    2015-10-01

    Full Text Available Purpose: to determine structural model of in-group dynamic of 6-10 years old boys’ motor fitness. Material: in the research 6 years old boys (n=48, 7 years old (n=45, 8 years old (n=60, 9 years’ age (n=47 and10 years’ age (n=40 participated. We carried out analysis of factorial model of schoolchildren’s motor fitness. Results: we received information for taking decisions in monitoring of physical education. This information is also necessary for working out of effective programs of children’s and adolescents’ physical training. We determined model of motor fitness and specified informative tests for pedagogic control in every age group. In factorial model of boys’ motor fitness the following factor is the most significant: for 6 years - complex development of motor skills; for 7 years - also complex development of motor skills; for 8 years - strength and coordination; for 9 years - complex development of motor skills; for 10 years - complex development of motor skills. Conclusions: In factorial model of 6-10 years old boys’ motor fitness the most significant are backbone and shoulder joints’ mobility, complex manifestation of motor skills, motor coordination. The most informative tests for assessment of different age boys’ motor fitness have been determined.

  6. Annual incidences of visual impairment during 10-year period in Mie prefecture, Japan.

    Science.gov (United States)

    Ikesugi, Kengo; Ichio, Takako; Tsukitome, Hideyuki; Kondo, Mineo

    2017-07-01

    To determine the annual incidence of visual impairment in a Japanese population during a 10-year period. We examined the physical disability certificates issued yearly between 2004 and 2013 in Mie prefecture, Japan. During this period 2468 visually impaired people were registered under the newly defined Act on Welfare of the Physically Disabled Persons' criteria. The age, sex distribution, and causes of visual impairment were determined from the certificates. The major causes of visual impairment during the ten-year period were glaucoma (23.3%), diabetic retinopathy (17.3%), retinitis pigmentosa (12.2%), macular degeneration (9.0%), chorioretinal degeneration or high myopia (7.4%), optic atrophy (5.8%), stroke or brain tumor (5.4%) and cataracts (3.7%). The incidence of glaucoma was significantly higher throughout the period (2004-2013), and that of diabetic retinopathy was lower between 2007 and 2013. The incidence of retinitis pigmentosa did not change significantly during the 10-year period. The incidence of macular degeneration tended to increase between 2004 and 2007, but it decreased significantly between 2007 and 2013. The results indicate that in Japan, the rates of the major causes of visual impairment altered in the most recent 10-year period reflecting the recent changes in the social background and advances in ocular and systemic treatment.

  7. Parameters of effective competition activity and selection of young gymnasts in age 9-10 years

    Directory of Open Access Journals (Sweden)

    Bolyak A.A.

    2014-03-01

    Full Text Available Purpose: to determine the effective factors of competitive activities and criteria for selection of young gymnasts at the stage of preliminary basic training based on the tests of motor skills and physiological parameters using methods of statistical analysis. Material : results of psychophysical testing, anthropometry, data on the development of motor abilities of young gymnasts of 9-10 years and assessment of their technical training. The study group consisted of 29 young gymnasts aged 9-10 years. All of them had a sports category corresponding their ages. Results: among the sixteen benchmarks psychophysiological data figures stepwise regression equation determined the four most important factors that influence the effectiveness of the competitive activities of the young athletes. The stepwise regression equation allowed lowing the most influential factor affecting the competitive activity among anthropometric and motor performance from twenty- eight to twelve most significant factors. Conclusions: The application of regression analysis and stepwise regression method allowed developing the mathematical models of the efficiency of competitive activities of the gymnasts of 9-10 years that can be used in the practice of selection children for the pre basic training.

  8. Deterioration of mental health in bariatric surgery after 10 years despite successful weight loss.

    Science.gov (United States)

    Canetti, L; Bachar, E; Bonne, O

    2016-01-01

    The present study evaluated the mental health and psychological functioning of bariatric patients before surgery, and after 1 year and 10 year follow-ups, and compared them with participants in a dietary program. Such long follow-up is rare, but strongly recommended by the American Association of Bariatric Surgeons. Thirty-six bariatric surgery patients and 34 participants of a weight loss program were weighed and assessed at all 3 points in time. Participants were administered the mental health inventory, neuroticism, sense of control and fear of intimacy scales. Along with these mental and psychological measurements, the medical outcome short form (SF-36) was used. The surgery group achieved successful weight loss outcomes (27% reduction of pre-operative weight) after 10 years and better than baseline health-related quality-of-life scores. However, their general mental health, neuroticism, sense of control and fear of intimacy scores showed significant deterioration in comparison to pre-operative levels after 10 years. The dietary group participants remained psychologically stable among all three points in time. This study highlights the importance of identifying a risk group among bariatric patients for which the dietary and psychological follow-up may be of special significance.

  9. Nutrition Needs Assessment of Young Special Olympics Participants

    Science.gov (United States)

    Gibson, Jennifer C.; Temple, Viviene A.; Anholt, Jane P.; Gaul, Catherine A.

    2011-01-01

    Background: Children with intellectual disability (ID) are at increased risk for obesity and nutrition-related health concerns, yet there is a paucity of data describing their nutrition status. The purpose of this study was to evaluate nutritional challenges of young participants (2-10 years of age) enrolled in Special Olympics Canada (SOC)…

  10. A high energy intake from dietary fat among middle-aged and older adults is associated with increased risk of malnutrition 10 years later.

    Science.gov (United States)

    Söderström, Lisa; Rosenblad, Andreas; Adolfsson, Eva T; Wolk, Alicja; Håkansson, Niclas; Bergkvist, Leif

    2015-09-28

    A higher fat content in the diet could be an advantage for preventing malnutrition among older adults. However, there is sparse scientific evidence to determine the optimal fat intake among older adults. This prospective cohort study examined whether a high energy intake of dietary fat among middle-aged and older adults is associated with the risk of malnutrition 10 years later. The study population comprised 725 Swedish men and women aged 53-80 years who had completed a questionnaire about dietary intake and lifestyle factors in 1997 (baseline) and whose nutritional status was assessed when admitted to the hospital in 2008-2009 (follow-up). At the follow-up, 383 (52.8%) participants were identified as being at risk of malnutrition and fifty-two (7.2%) were identified as malnourished. Multinomial logistic regression models were used to analyse the association between previous dietary fat intake and nutritional status later in life. Contrary to what was expected, a high energy intake from total fat, saturated fat and monounsaturated fat among middle-aged and older adults increased the risk of exhibiting malnutrition 10 years later. However, this applied only to individuals with a BMImalnutrition in older adults should focus on limiting the intake of total fat in the diet by reducing consumption of food with a high content of saturated and monounsaturated fat.

  11. The US Army Burn Center: Professional Service During 10 Years of War

    Science.gov (United States)

    2012-01-01

    shear or loss and worsened surgical outcomes. Our armamentarium to optimize analgesia includes neuraxial ap- proaches to perioperative analgesia ...exposure keratitis, correc- tion of microstomia to improve dental hygiene and nutrition, and coverage of exposed bone, tendons, or nerves often seen

  12. The SENECA study: potentials and problems in relating diet to survival over 10 years

    NARCIS (Netherlands)

    Staveren, van W.A.; Groot, de C.P.G.M.; Haveman-Nies, A.

    2002-01-01

    Objective: To give an overview of the evaluation of the modified diet history applied in the SENECA study (Survey in Europe on Nutrition and the Elderly; a Concerted Action). Design: Nineteen centres in 12 countries participated at baseline. Nine of these SENECA centres conducted a repeat measuremen

  13. Iodine Status of School-children (8-10 years) and Associated ...

    African Journals Online (AJOL)

    iodine nutrition. From a sub-sample oj 50 households, 50 salt samples used in the ... Millet diets have also been documented to be ... of dietary intake of gOitrogens is ... have heard of iodine and 100, knew ..... has been recommended for the.

  14. DIETARY HABITS of CHILDREN 5-10 Years old: A Hospital Based Study

    Directory of Open Access Journals (Sweden)

    Shantanu Sharma

    2015-01-01

    Full Text Available Introduction: In developing countries research in nutrition has primarily be focusing on preschool children and women of reproductive age.1,2 A large, multicountry study on the anthropometric status of rural school children in Ghana, Tanzania, Indonesia, Vietnam, and India found a high prevalence of stunting and underweight, ranging from 48% to 56% for stunting and from 34% to 62% for underweight.1 Anemia is estimated to affect 46% of 5- to 12-year-old children in low-income countries, with the highest prevalence in South Asia (50%.2 Because school-age children undergo a period of rapid growth, nutrient deficiencies at this age can lead to retarded growth3, anemia2, reduced immune function4 and impaired motor and cognitive development5, all of which may adversely affect academic performance through reduced learning capacity and poor school attendance6. Nutritional deficiency in children of school going age result from increased micronutrient needs for growth, as well as changes in eating and lifestyle habits arising from increasing independence from the family. During this time, nutritional requirements are high, yet vitamin and mineral intakes tend to be reduced as there is a greater consumption of ‘empty calories’, frequent meal skipping, adoption of inappropriate weight control behavior and decreased vegetable and fruit intake.7,8,9 In spite of the fact that in many countries much is known about the nutritional situation of children and adolescents10-16, less information is available for this age group than for adults, and no data exist on risk factors associated with inadequate intakes in the younger cohort. The quantity and quality of available information is scarce. There is mutual synergistic interrelationship between infections and nutritional status. Poor nutritional status increases the likelihood of acquiring an infectious disease and increased severity of infectious episode whereas infectious disease leads to worsening of

  15. Safety of Quadrivalent Meningococcal Conjugate Vaccine in Children 2-10 Years.

    Science.gov (United States)

    Tartof, Sara Y; Sy, Lina S; Ackerson, Bradley K; Hechter, Rulin C; Haag, Mendel; Slezak, Jeffrey M; Luo, Yi; Fischetti, Christine A; Takhar, Harp S; Miao, Yan; Solano, Zendi; Jacobsen, Steven J; Tseng, Hung-Fu

    2017-07-14

    Quadrivalent meningococcal conjugate vaccine is recommended for children, adolescents, and adults at increased risk of meningococcal disease. In 2011, MenACWY-CRM (Menveo, GSK) was approved for children aged 2-10 years in the U.S. Although no safety concerns arose from clinical trials, it remains important to monitor its safety in routine clinical settings. Kaiser Permanente Southern California members 2-10 years old who received MenACWY-CRM between September 2011 and September 2014 were included. Electronic health records were searched using a validated algorithm to identify 26 pre-specified events of interest (EOIs) and serious medically attended events (SMAEs) from inpatient or emergency settings up to one year following MenACWY-CRM vaccination. SMAEs were categorized by ICD-9 diagnostic categories. All events were reviewed to confirm the diagnosis and symptom onset date. The study was descriptive (NCT01452438); no statistical tests were performed. Among 387 vaccinated children, 327 with ≥6 months membership before vaccination were analyzed. Among EOIs, 9 asthma cases and one myasthenia gravis case underwent chart review which confirmed one incident asthma case occurring 237 days after concomitant vaccination with MenACWY-CRM and typhoid vaccine. Thirty-one children experienced SMAEs, most commonly due to unrelated injury and poisoning. The remaining events occurred sporadically after vaccination and most were unlikely related to vaccination based on medical record review. One incident EOI of asthma late in the 1-year observation period and sporadic distribution of SMAEs were observed. These data do not suggest safety concerns associated with MenACWY-CRM vaccination in children 2-10 years old.

  16. Development of 5- and 10-year-old pediatric phantoms based on polygon mesh surfaces

    Energy Technology Data Exchange (ETDEWEB)

    Melo Lima, V. J. de; Cassola, V. F.; Kramer, R.; Oliveira Lira, C. A. B. de; Khoury, H. J.; Vieira, J. W. [Department of Anatomy, Federal University of Pernambuco, Avenida Professor Moraes Rego 1235, CEP 50670-901, Recife, Pernambuco (Brazil); Department of Nuclear Energy, Federal University of Pernambuco, Avenida Professor Luiz Freire 1000, CEP 50740-540, Recife, Pernambuco (Brazil); Federal Institute of Education, Science and Technology of Pernambuco, Avenida Professor Luiz Freire 500, CEP 50740-540, Recife, Pernambuco, Brazil and Polytechnic School of Pernambuco, University of Pernambuco, Rua Benfica 455, CEP 50751-460, Recife, Pernambuco (Brazil)

    2011-08-15

    Purpose: The purpose of this study is the development of reference pediatric phantoms for 5- and 10-year-old children to be used for the calculation of organ and tissue equivalent doses in radiation protection. Methods: The study proposes a method for developing anatomically highly sophisticated pediatric phantoms without using medical images. The 5- and 10-year-old male and female phantoms presented here were developed using 3D modeling software applied to anatomical information taken from atlases and textbooks. The method uses polygon mesh surfaces to model body contours, the shape of organs as well as their positions, and orientations in the human body. Organ and tissue masses comply with the corresponding data given by the International Commission on Radiological Protection (ICRP) for the 5- and 10-year-old reference children. Bones were segmented into cortical bone, spongiosa, medullary marrow, and cartilage to allow for the use of micro computer tomographic ({mu}CT) images of trabecular bone for skeletal dosimetry. Results: The four phantoms, a male and a female for each age, and their organs are presented in 3D images and their organ and tissue masses in tables which show the compliance of the ICRP reference values. Dosimetric data, calculated for the reference pediatric phantoms by Monte Carlo methods were compared with corresponding data from adult mesh phantoms and pediatric stylized phantoms. The comparisons show reasonable agreement if the anatomical differences between the phantoms are properly taken into account. Conclusions: Pediatric phantoms were developed without using medical images of patients or volunteers for the first time. The models are reference phantoms, suitable for regulatory dosimetry, however, the 3D modeling method can also be applied to medical images to develop patient-specific phantoms.

  17. Vertical scar versus the inverted-T scar reduction mammaplasty: a 10-year follow-up.

    Science.gov (United States)

    Bouwer, Lesley R; van der Biezen, Jan Jaap; Spronk, Cees A; van der Lei, Berend

    2012-10-01

    A retrospective study was undertaken to evaluate whether the initial outcome of two types of reduction mammaplasty techniques (vertical scar reduction mammaplasty vs. the inverted-T scar reduction mammaplasty) remains stable in the long term: Sixty-nine patients who had undergone breast reduction surgery in the period 1997-2000 at the Department of Reconstructive Plastic Surgery at the Medical Center of Leeuwarden were willing and able to participate in this study. A structured questionnaire was used to assess the degree of patient satisfaction. For subjective evaluation, the Strasser Grading System on photographs at the 3 months after surgery and after long-term follow-up (10 years) was used. The median general appreciation mark for the entire surgical procedure given by patients was 8 (1-10) on a scale from 1 to 10. Forty-six of the 69 patients could be scored according to Strasser: at 3 months in 17 patients (37%) the result was 'good', in 21 patients (46%) 'mediocre' and in eight patients (17%) 'poor'. After 10 years, in 37 of the patients (80%) the result was 'good', in six patients (13%) 'mediocre' and in three patients (7%) 'poor'. At 3 months, there was a higher incidence of bottoming out in the vertical scar group (one on two patients) as compared to the inverted-T scar group (one on 10 patients); however, at the 10-years follow-up bottoming out was 50% in the inverted-T scar group and 20% in the vertical scar group. Despite bottoming out, in both the vertical scar reduction mammaplasty technique and the inverted-T scar reduction mammaplasty technique, high patient satisfaction rates are achieved that remains for years.

  18. Peroral Endoscopic Myotomy for the Treatment of Achalasia in a 10-Year-Old Male Patient.

    Science.gov (United States)

    Filser, Jörg; Dick, Anke; Meyer, Thomas; Germer, Christoph-Thomas; von Rahden, Burkard H A

    2015-06-01

    Peroral endoscopic myotomy (POEM) is a new endoscopic treatment for achalasia with very good short-term results in adults. Data about POEM in pediatric patients are missing. We present the case of a 10-year-old male patient with type I (classic) achalasia, successfully treated with POEM. The procedure was accomplished in a similar fashion to the technique used in adults. Short-term results were fine, with a complete control of dysphagia and absence of reflux. We suggest that POEM is a suitable option in pediatric patients-similar to adults-but long-term results must be awaited.

  19. Comorbid personality disorder predicts suicide after major depression: a 10-year follow-up

    DEFF Research Database (Denmark)

    Hansen, P E B; Wang, A G; Stage, K B;

    2003-01-01

    followed prospectively through a maximum of 10 years. Patients with a drug or alcohol abuse were excluded. The association between suicide and the pretreatment psychopathological profile was analysed using survival statistics. RESULTS: The suicide rate for non-melancholic depressed patients...... was significantly higher than for melancholic depressed patients. Comorbid personality disorder was independently associated with an increased suicide rate [relative hazard 3.41(CI: 1.15-10.10)]. CONCLUSION: The study indicates that the non-melancholic aspect of depression, and especially comorbid personality...... disorder, is associated with an increased suicidal vulnerability....

  20. Parathyroidectomy in the treatment of patients with chronic renal failure: a 10-year review.

    Science.gov (United States)

    Bessell, J R; Proudman, W D; Parkyn, R F; Disney, A P

    1993-01-01

    The technique and outcome of surgery for the manifestations of secondary hyperparathyroidism are described. Forty-seven patients were analysed retrospectively over a 10-year period. Total parathyroidectomy and autotransplantation to the forearm was performed in all but five patients. Improvement occurred in 87 per cent of patients and there were no graft failures. Of six deaths, none was related to surgery. Four patients had recurrent hyperparathyroidism, three being graft dependent and one requiring re-exploration of the neck. Total parathyroidectomy and autotransplantation is a safe and effective approach. The major management problem was graft hyperplasia, seen in three of the 47 patients and managed by simple excision.

  1. Mycoplasma pneumoniae associated organising pneumonia in a 10 year old boy.

    Science.gov (United States)

    Wachowski, O; Demirakça, S; Müller, K-M; Scheurlen, W

    2003-03-01

    We describe a 10 year old boy with organising pneumonia associated with acute Mycoplasma pneumoniae infection. The diagnosis of organising pneumonia was made by open lung biopsy and the M pneumoniae infection was proven serologically. Antibiotic and long term corticosteroid treatment resulted in steadily improving pulmonary function monitored by spirometry. The introduction of anti-inflammatory treatment with NSAIDs/immunosuppressive agents in order to spare steroids was well tolerated and resulted in further improvement of the pulmonary function. To our knowledge this is the first documented case of Mycoplasma pneumoniae associated organising pneumonia to be reported in a child.

  2. Malignant Nonfunctioning Neuroendocrine Neoplasm of the Pancreas in a 10-Year-Old Child

    Directory of Open Access Journals (Sweden)

    Ahmed Marwan

    2009-04-01

    Full Text Available Malignant neoplasms of the pancreas are extremely rare in children and only represent a small percentage of pediatric cancer-related deaths. The paucity of cases reported in the literature, in addition to the lack of understanding of biologic behavior, has led to a lack of consensus concerning optimal management strategy. Presentation differs compared to adult counterparts and generally prognosis is improved even when lymph node metastases occur. Here we review the literature and report the case of a 10-year-old autistic female with a malignant nonfunctioning pancreatic endocrine neoplasm of the head of the pancreas successfully extirpated via pancreaticoduodenectomy.

  3. Veneered zirconia inlay-retained fixed dental prostheses: 10-Year results from a prospective clinical study.

    Science.gov (United States)

    Rathmann, Friederike; Bömicke, Wolfgang; Rammelsberg, Peter; Ohlmann, Brigitte

    2017-09-01

    The purpose of this study was to evaluate the 10-year clinical performance of zirconia-based inlay-retained fixed dental prostheses (IRFDP). For replacement of a molar in 27 patients, 30 IRFDP were luted by use of different cements, Panavia F (Kuraray Europe GmbH) or Multilink Automix (Ivoclar Vivadent GmbH), with use of inlay/inlay, inlay/full-crown, or inlay/partial-crown retainers for anchorage. Frameworks were milled from yttria-stabilized zirconia (IPS e.maxZirCAD; Ivoclar Vivadent GmbH) and fully veneered with pressable ceramic (IPS e.max ZirPress; Ivoclar Vivadent GmbH). Before luting, the IRFDP were silica-coated (Rocatec; 3M Espe) and silanized (Monobond S; Ivoclar Vivadent GmbH). Complications (for example, chipping or delamination of the veneering ceramic, debonding, secondary caries, endodontic treatment, and abutment tooth fracture) and failure were reported, by use of standardized report forms, 2 weeks, 6 months, and 1, 2, and 10 years after cementation. Statistical analysis included Kaplan-Meier survival and success (complication-free survival) and Cox regression analysis (α=0.05 for all). During the 10-year observation period, the complications most often observed were chipping of the veneer and debonding. Twenty-five restorations failed and one participant dropped out. Cumulative 10-year survival and success were 12.1% and 0%, respectively. The design of the retainer, use of a dental dam, choice of cement, and location in the dental arch had no statistically significant effect on the occurrence of complications. Use of fully veneered zirconia-based IRFDP with this technique cannot be recommended. A large incidence of complications and poor survival were observed for fully veneered zirconia-based IRFDP, revealing an urgent need for further design improvements for this type of restoration. This, again, emphasizes the need for testing of new restoration designs in clinical trials before implementation in general dental practice. Copyright © 2017

  4. The drug-target residence time model: a 10-year retrospective.

    Science.gov (United States)

    Copeland, Robert A

    2016-02-01

    The drug-target residence time model was first introduced in 2006 and has been broadly adopted across the chemical biology, biotechnology and pharmaceutical communities. While traditional in vitro methods view drug-target interactions exclusively in terms of equilibrium affinity, the residence time model takes into account the conformational dynamics of target macromolecules that affect drug binding and dissociation. The key tenet of this model is that the lifetime (or residence time) of the binary drug-target complex, and not the binding affinity per se, dictates much of the in vivo pharmacological activity. Here, this model is revisited and key applications of it over the past 10 years are highlighted.

  5. Jejunal intussusception in a 10-year-old boy with blue rubber bleb nevus syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Beluffi, Giampiero [Section of Paediatric Radiology, Department of Radiodiagnosis, IRCCS Policlinico S. Matteo, Piazzale Golgi, 2, 27100, Pavia PV (Italy); Romano, Piero; Matteotti, Chiara; Minniti, Silvio; Ceffa, Franco [Division of Paediatric Surgery, IRCCS Policlinico S. Matteo, Pavia (Italy); Morbini, Patrizia [Department of Pathology, IRCCS Policlinico S. Matteo, Pavia (Italy)

    2004-09-01

    Jejunal intussusception in a Chinese 10-year-old boy affected by the blue rubber bleb nevus syndrome is presented and discussed. The syndrome is rare, sporadically found with possible dominant inheritance, and due to a gene mutation mapped on the short arm of chromosome 9. It presents with distinctive cutaneous and gastrointestinal malformations together with possible other organ involvement. Gastrointestinal malformations tend to bleed and lead to anaemia. Infrequent complications of the gastrointestinal malformations are volvulus, intestinal infarction and intussusception. The age of the patient and the jejunal intussusception precipitated by a vascular malformation containing calcifications (which were also found in different gut segments) make this case remarkable. (orig.)

  6. A 10-Year Prospective Study of Single Tooth Implants Placed in the Anterior Maxilla

    DEFF Research Database (Denmark)

    Gotfredsen, Klaus

    2012-01-01

    in this study. Ten implants were placed with an early placement protocol, that is, 4 weeks after tooth extraction, whereas the other 10 implants were placed with a conventional delayed placement protocol, for example, 12 weeks after tooth extraction. At the baseline and at the annual re-examinations, pain from......Purpose: The aim of the study was to evaluate the biological and technical outcomes of early and delayed placed single tooth implants after 10 years of follow-up. Materials and Methods: Twenty consecutive patients who needed a single tooth replacement in the anterior maxilla were included...

  7. Pulmonary talcosis 10 years after brief teenage exposure to cosmetic talcum powder.

    Science.gov (United States)

    Shakoor, Amarah; Rahatullah, Arsalan; Shah, Adil Aijaz; Zubairi, Ali Bin Sarwar

    2011-09-19

    Pulmonary talcosis is a rare but debilitating variant of pneumoconiosis often presenting with isolated non-specific symptoms of progressive exertional dyspnoea or cough. Occupational exposure to talc dust and intravenous drug abuse are well-recognised aetiological factors with only a few cases related to cosmetic talc exposure being reported to date. The authors report a case of a young woman in whom a mere 4 month ritual of inhaling cosmetic talcum powder led to full-blown pulmonary talcosis being diagnosed 10 years later. The importance of a taking a pertinent history relating to environmental exposures in all patients presenting with respiratory symptoms is re-established here.

  8. Malignant Nonfunctioning Neuroendocrine Neoplasm of the Pancreas in a 10-Year-Old Child.

    Science.gov (United States)

    Marwan, Ahmed; Christein, John D

    2009-04-17

    Malignant neoplasms of the pancreas are extremely rare in children and only represent a small percentage of pediatric cancer-related deaths. The paucity of cases reported in the literature, in addition to the lack of understanding of biologic behavior, has led to a lack of consensus concerning optimal management strategy. Presentation differs compared to adult counterparts and generally prognosis is improved even when lymph node metastases occur. Here we review the literature and report the case of a 10-year-old autistic female with a malignant nonfunctioning pancreatic endocrine neoplasm of the head of the pancreas successfully extirpated via pancreaticoduodenectomy.

  9. Maturogenesis of Two Maxillary Central Incisors: A Case Report with 10 Years of Follow Up.

    Science.gov (United States)

    Ghorbanzadeh, Abdollah; Ghorbanzadeh, Atiyeh

    2015-04-01

    This case report describes the treatment of two immature maxillary central incisors in a 7-year-old female patient. She suffered complicated crown fracture because of trauma, and the root formation was incomplete. White mineral trioxide aggregate (MTA) was selected as the pulp-capping material after cervical pulpotomy to preserve the pulp tissue vitality and achieve maturogenesis. Follow-up evaluations showed successful treatment in terms of preservation of pulp vitality and demonstrated marked continuous physiological root development. During 10 years of follow-up, both teeth were clinically asymptomatic, and radiographic evaluations showed apparent root regeneration with apical root-end closure without pulp or periapical pathosis.

  10. Massive fibrous epulis-a case report of a 10-year-old lesion

    Institute of Scientific and Technical Information of China (English)

    Gabriel MFonseca; Ricardo MFonseca; Mario Cantn

    2014-01-01

    The fibrous epulis, a common tumor-like lesion of the gingiva, appears in the interdental papilla as a result of local irritation. Lesions are asymptomatic and have a variable growth rate. A 75-year-old woman was referred for the evaluation of a large painless gingival mass. It had started 10 years back and has been increasing in size the last year. No bone involvement was noted. The tumor was totally removed by excision with surgical scalpel under local anesthesia without teeth extraction. The microscopic findings were suggestive of a fibrous epulis. Differential diagnosis, clinical considerations and factors to prevent recurrence are discussed.

  11. Universitas Psychologica: 10 Years of Constant Change in Editorial and Content Management

    OpenAIRE

    López López, Wilson; Pontificia Universidad Javeriana

    2011-01-01

    Our journal is turning 10 years old in 2011. During this period, we have experienced deep and significant transformations, that have led us to change our printed format and to modify the Web proposal, which has merged an aesthetical development with the Open Journal System (OJS) for content management. This web has generated two published articles, where we show how our proposal is a model for journal websites all around the world (the articles can be found in http://journals.sfu.ca/src/in...

  12. Mineral Trioxide Aggregate (MTA direct pulp capping: 10 years clinical results

    Directory of Open Access Journals (Sweden)

    Lucio Daniele

    2017-06-01

    After 10-years follow-up period, 6 out of 80 teeth required an endodontic treatment, we did not find an increase of pulp calcifications, root resorptions, endodontic lesions. All teeth still alive have responded positively to the cold-temperature test. The three lesions had disappeared at the last X-ray control. All four symptomatic teeth preserved their pulp vitality. The successful treatment rate was 92.5%. Direct pulp capping with MTA can be considered an effective treatment of exposure due to tooth decay and can be considered a valid treatment option for teeth with a diagnosis of not-severe reversible pulpitis.

  13. Pyridoxine-dependent seizures: 10-year follow-up of eight cases

    Directory of Open Access Journals (Sweden)

    Koul Roshan

    2009-01-01

    Full Text Available Eight children with pyridoxine-dependent seizures (PDS were seen over a period of 10 years. Of those children, 6 are on regular follow-up. Four of the children were seen in one family. All the patients presented with refractory seizures, mainly neonatal status epilepticus. Though PDS is a rare condition, it must be considered in all cases with refractory seizures, particularly in childrens younger than 3 years. When confirming a diagnosis, oral pyridoxine is as effective as intravenous pyridoxine.

  14. Diet & Nutrition

    Science.gov (United States)

    ... Nutrition Share this page Facebook Twitter Email Diet & Nutrition Eating healthy to take charge of your health. Shelly Diagnosed in 2006 Diet & Nutrition Take Control of Your Weight Portion Control Low ...

  15. What factors influence motor complications in Parkinson disease?: a 10-year prospective study.

    Science.gov (United States)

    García-Ruiz, Pedro J; Del Val, Javier; Fernández, Ignacio Mahillo; Herranz, Antonio

    2012-01-01

    The causes and mechanism behind motor complications in Parkinson disease (PD) are still a subject of debate. Several factors including age at onset, evolution in years, and initial medication can influence the onset and severity of motor complications in PD.We studied patients with recent diagnosis of PD who were followed up prospectively for 10 years. Analysis included the progression of these patients, as measured by the Unified Parkinson Disease Rating Scale scores and the presence of motor complications (motors fluctuations, dyskinesias, and gait freezing) over time. The patient group was studied as a whole and by subgroups classified according to age at onset, initial treatment, and sex.By the end of the first decade, most patients exhibited dyskinesias (91%), motor fluctuations (62%), and freezing of gait (68%). An association was found between several patients' characteristics and presence of motor complications by 5 years, though not after 10 years of follow up. The apparition of motor fluctuations was mainly related to initial treatment (odds ratio [OR], 3.87). The development of dyskinesias was linked to initial treatment (OR, 8.31), age at onset (OR, 0.90), and sex (OR, 12.87).

  16. Is maternal education level associated with diet in 10-year-old children?

    Science.gov (United States)

    Cribb, Victoria L; Jones, Louise R; Rogers, Imogen S; Ness, Andrew R; Emmett, Pauline M

    2011-11-01

    To examine the associations between maternal education level and diet in 10-year-old children. Three-day diet diaries (child completed with parental help) were collected. Height and weight were measured in research clinics. Maternal education level was derived from a questionnaire completed during pregnancy and classified into low, medium or high. One-way ANOVA was undertaken to compare maternal education groups for nutrient intakes and the Kruskal-Wallis test used for food consumption. Avon Longitudinal Study of Parents and Children (ALSPAC), Bristol, UK. Children (n 7474) who provided dietary data at age 10 years. A large proportion (60 %) of the sample was classified as plausible reporters, with under-reporting accounting for 36 %. No clear differences were found for intakes of energy or macronutrients between maternal education groups for plausible reporters. However, there were marked differences in micronutrient intakes especially for vitamin C, retinol equivalents and folate, highlighting lower diet quality with lower maternal education level. Intakes of fruit and vegetables showed a positive gradient with increasing maternal education (57 % v. 79 % consumed fresh fruit in low and high educational groups, respectively). A trend towards higher intake in the lower educated group was shown for less healthy foods (meat pies P education level. Lower maternal education was associated with less healthy food choices that could be detrimental to health. Further research is needed to establish if these associations can be explained by other socio-economic factors.

  17. Customising turnaround time indicators to requesting clinician: a 10-year study through balanced scorecard indicators.

    Science.gov (United States)

    Salinas, Maria; López-Garrigós, Maite; Santo-Quiles, Ana; Gutierrez, Mercedes; Lugo, Javier; Lillo, Rosa; Leiva-Salinas, Carlos

    2014-09-01

    The purpose of this study is, first to present a 10-year monitoring of postanalytical turnaround time (TAT) adapted to different clinicians and patient situations, second to evaluate and analyse the indicators results during that period of time, and finally to show a synthetic appropriate indicator to be included in the balanced scorecard management system. TAT indicator for routine samples was devised as the percentage of certain key tests that were verified before a specific time on the phlebotomy day. A weighted mean synthetic indicator was also designed. They were calculated for inpatients at 15:00 and 12:00 and for primary care patients only at 15:00. The troponin TAT of emergency department patients, calculated as the difference between the troponin verification and registration time, was selected as the stat laboratory TAT indicator. The routine and stat TAT improved along the 10-year study period. The synthetic indicator showed the same trend. The implementation of systematic and continuous monitoring over years, promoted a continuous improvement in TAT which will probably benefit patient outcome and safety.

  18. Overview of Aqua MODIS 10-year on-orbit calibration and performance

    Science.gov (United States)

    Xiong, X.; Wenny, B.; Sun, J.; Angal, A.; Wu, A.; Chen, H.; Choi, T.; Madhavan, S.; Geng, X.; Link, D.; Wang, Z.; Toller, G.; Barnes, W.; Salomonson, V.

    2012-09-01

    Since launch in May 2002, Aqua MODIS has successfully operated for over 10 years, continuously collecting global datasets for scientific studies of key parameters of the earth's land, ocean, and atmospheric properties and their changes over time. The quality of these geophysical parameters relies on the input quality of sensor calibrated radiances. MODIS observations are made in 36 spectral bands with wavelengths ranging from visible (VIS) to long-wave infrared (LWIR). Its reflective solar bands (RSB) are calibrated using data collected from its on-board solar diffuser and regularly scheduled lunar views. The thermal emissive bands (TEB) are calibrated using an on-board blackbody (BB). The changes in the sensor's spectral and spatial characteristics are monitored by an on-board spectroradiometric calibration assembly (SRCA). This paper presents an overview of Aqua MODIS 10-year on-orbit operation and calibration activities, from launch to present, and summarizes its on-orbit radiometric, spectral, and spatial calibration and characterization performance. In addition, on-orbit changes in sensor characteristics and corrections applied to continuously maintain level 1B (L1B) data quality are discussed, as well as lessons learned that could benefit future calibration efforts.

  19. Resistance studies of erythromycin and rifampin for Rhodococcus equi over a 10-year period

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    Buckley T

    2007-12-01

    Full Text Available Abstract This study sought to determine whether an increase in resistance of Rhodococcus equi to the antibiotics rifampin and erythromycin occurred over a 10-year period. This was carried out by the use of E test strips for rifampin and erythromycin to determine the MIC (minimum inhibitory concentration values of Rhodococcus equi to this combination of antibiotics. The findings of this study indicated that there was an increase in resistance of Rhodococcus equi to rifampin and erythromycin over the 10-year period. The MIC for rifampin increased from 0.081 μg/ml in 1996 to 0.187 μg/ml in 2006 and from 0.258 μg/ml for erythromycin during the years prior to 2000 to 0.583 μg/ml in 2006. This finding suggests that there may be a problem in the treatment of Rhodococcus equi infections in foals in the future, particularly as the number of drugs available for treatment of Rhodococcus equi infection is limited because of the intracellular capabilities of this bacterium. Antibiotics used in its treatment have to be able to penetrate the polysaccharide cell wall of Rhodococcus equi as well as the alveolar macrophages in which the bacterium is capable of surviving.

  20. Foreign body aspiration and language spoken at home: 10-year review.

    Science.gov (United States)

    Choroomi, S; Curotta, J

    2011-07-01

    To review foreign body aspiration cases encountered over a 10-year period in a tertiary paediatric hospital, and to assess correlation between foreign body type and language spoken at home. Retrospective chart review of all children undergoing direct laryngobronchoscopy for foreign body aspiration over a 10-year period. Age, sex, foreign body type, complications, hospital stay and home language were analysed. At direct laryngobronchoscopy, 132 children had foreign body aspiration (male:female ratio 1.31:1; mean age 32 months (2.67 years)). Mean hospital stay was 2.0 days. Foreign bodies most commonly comprised food matter (53/132; 40.1 per cent), followed by non-food matter (44/132; 33.33 per cent), a negative endoscopy (11/132; 8.33 per cent) and unknown composition (24/132; 18.2 per cent). Most parents spoke English (92/132, 69.7 per cent; vs non-English-speaking 40/132, 30.3 per cent), but non-English-speaking patients had disproportionately more food foreign bodies, and significantly more nut aspirations (p = 0.0065). Results constitute level 2b evidence. Patients from non-English speaking backgrounds had a significantly higher incidence of food (particularly nut) aspiration. Awareness-raising and public education is needed in relevant communities to prevent certain foods, particularly nuts, being given to children too young to chew and swallow them adequately.

  1. Endovascular coil embolization for recurrence of intracranial aneurysms more than 10 years after clipping

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    Naoya Takeda

    2013-01-01

    Full Text Available We report three cases of endovascular coil embolization for recurrent cerebral aneurysm after neck clipping more than 10 years previously. In two cases, their first subarachnoid hemorrhage was treated in other hospitals and the details of follow-up after discharge were unknown. After their second subarachnoid hemorrhage recurred 15 and 30 years, respectively. The remaining patient, who was treated in our center, was followed by magnetic resonance imaging 5 years after surgery but since then she didn′t go to our center. She came to our center for follow-up examination 10 years after the first surgery. The digital subtraction angiography showed recurrence of clipped aneurysms in all patients. All of them underwent endovascular coil embolization and total obliteration of the aneurysms without complications related to the procedures. Endovascular coil embolization is an alternative modality to direct surgery for cerebral aneurysms, especially for recurrence after clipping. Endovascular coil embolization of residual aneurysms after surgery may be the treatment of choice because of the difficulties in second direct surgery. We conclude that it is necessary to perform follow-up evaluations after surgery, even if the complete obliteration of aneurysms is performed. Current medical literature does not provide recommendations for the duration of follow-up after aneurysm clipping. The authors suggest that this period perhaps be at least a decade.

  2. Evaluation of 6 and 10 Year-Old Child Human Body Models in Emergency Events

    Science.gov (United States)

    2017-01-01

    Emergency events can influence a child’s kinematics prior to a car-crash, and thus its interaction with the restraint system. Numerical Human Body Models (HBMs) can help understand the behaviour of children in emergency events. The kinematic responses of two child HBMs–MADYMO 6 and 10 year-old models–were evaluated and compared with child volunteers’ data during emergency events–braking and steering–with a focus on the forehead and sternum displacements. The response of the 6 year-old HBM was similar to the response of the 10 year-old HBM, however both models had a different response compared with the volunteers. The forward and lateral displacements were within the range of volunteer data up to approximately 0.3 s; but then, the HBMs head and sternum moved significantly downwards, while the volunteers experienced smaller displacement and tended to come back to their initial posture. Therefore, these HBMs, originally intended for crash simulations, are not too stiff and could be able to reproduce properly emergency events thanks, for instance, to postural control. PMID:28099505

  3. [Food avoidance emotional disorder in 3 to 10-year-old children: a clinical reality].

    Science.gov (United States)

    Goëb, J-L; Azcona, B; Troussier, F; Malka, J; Giniès, J-L; Duverger, P

    2005-09-01

    We underline the clinical importance of a specific eating disorder in 3 to 10 years old children, when the majority of the works about the prepubertal eating disorders focus either on the period just preceding adolescence (often between 10 and 13 years), or on the second half of the first year of the baby. Within the eating disorders described in the literature, we compare the clinical presentation of most of these 3 to 10 years old children with the food avoidance emotional disorder described during adolescence. These problems of eating behaviour (various selective eating with or without provoked vomiting) are ignored for a long time in these young children because of quite a satisfactory growth, but these children are often seen in emergency rooms because of a brutally complete eating refusal. Therapeutic consultations allow these children to express their fears about diseases, poisoning and death, for themselves or for their close relations, in particular the mother, without endangering their body. The early recognition and care of these difficulties of conciliation between the body and the thoughts impose a narrow collaboration between paediatric and psychiatric staffs.

  4. Zoning of land reclamation in coal mining area and new progresses for the past 10 years

    Institute of Scientific and Technical Information of China (English)

    Wu Xiao; Zhenqi Hu; Yanhua Fu

    2014-01-01

    Coal mining disturbed land is the main sources of land reclamation in China. With the rapid increase of economy and coal production, more and more land has been disturbed by construction and coal mining; thus, land reclamation has become highlights in the past 10 years, and China is boosting land reclamation in mining areas. Distur-bance characteristics vary from region to region, according to natural and geological conditions, coal mining area land reclamation was divided into 3 zones, which are eastern, western and southern. Reclamation strategies are focused on prime farmland protection in eastern and ecological restoration in western and southern zones, respectively. Several innovative reclamation technologies and theories for the past 10 years were introduced in this paper, including concurrent mining and reclamation, Yellow river sediments backfilling, self-reclamation, and topsoil alternatives in opencast mines. Besides, in the government regulation and legal system building respect, several important laws and regulations were issued and implemented in the past 5 years, promoting land reclamation management and supervision greatly. Land reclamation is and will still be one of the most important parts of coal industry in the future, and more efforts and funds are expected to get involved.

  5. Initial 10-year Experience of Sperm Cryopreservation Services for Cancer Patients

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    Hong-Chiang Chang

    2006-01-01

    Full Text Available Offering sperm cryopreservation to preserve the fertility of male cancer patients is a relatively recent service in Asia. This study analyzed the types of cancer, timing of collection, sperm quality, and utilization for reproductive services by patients during a 10-year period at a medical center in Taiwan. A total of 75 oncology patients elected to freeze sperm for fertility preservation at our medical center during the initial 10 years of the availability of this service. The mean age of the patients was 25.7 years. Storage was discontinued in 13 (17% patients and their survival duration was 13.1 ±11.1 months. The utilization rate of sperm cryo-preservation was 2.8% (75/2642. The types of cancer varied, with leukemia (35%, lymphoma (25%, and testicular cancer (13% comprising the largest groups. A significantly lower sperm count was found in patients with chronic myelogenous leukemia, suggesting the need for earlier sperm collection after initiation of cancer treatment. Only three (4% patients utilized their specimens for reproductive purposes. There was no clinical pregnancy during the study period, although one biochemical pregnancy was achieved. The low rates of sperm cryostorage for fertility preservation in cancer patients in this study suggest that there is a need for greater emphasis of this option for male oncology patients whose fertility is likely to be affected by chemotherapeutic treatment.

  6. Stump appendicitis 10 years after appendectomy, a rare, but serious complication of appendectomy, a case report.

    Science.gov (United States)

    Van Paesschen, Carl; Haenen, Filip; Bestman, Raymond; Van Cleemput, Marc

    2017-02-01

    We describe a case of stump appendicitis with the formation of abdominal abscesses in a 41-year-old patient 10 years prior appendectomy. The patient consulted with fever (38.1 °C) and abdominal pain, located at the right iliac fossa. Imaging studies showed signs of abscesses, located at the right iliac fossa, without clear origin of these abscesses. The abscesses were drained through diagnostic laparoscopy, no bowel perforation or clear origin of the abscedation was found during laparoscopy. During postoperative stay, the inflammatory parameters rose and the abscesses reoccurred. Re-laparoscopy was performed, the abscesses were drained and on careful inspection and adhesiolysis, a perforated stump appendicitis was revealed, covered underneath layers of fibrous tissue. Stump appendicitis is a rare complication seen after appendectomy and is generally not considered a possible etiology in patients presenting with fever and right iliac fossa abdominal pain with a history of appendectomy. This often delays the correct diagnosis and results in an associated increased incidence of complications. We describe a case of stump appendicitis occurring 10 years after initial appendectomy.

  7. Evolution in Practice: How has British Neurosurgery Changed in the Last 10 Years?

    Science.gov (United States)

    Tarnaris, A; Arvin, B; Ashkan, K

    2008-01-01

    INTRODUCTION Neurosurgery is a fast-evolving surgical subspecialty driven by technological advances, socio-economic factors and patient expectations. In this study, we have compared the work-load volume in a single institution in the years of 1994 and 2004 and commented on the possible reasons for the changes and the impacts they may have for the future. PATIENTS AND METHODS A retrospective, log-book review of all operations performed in the years 1994 and 2004 in a single, tertiary, neurosurgical centre was performed. RESULTS Neurosurgical practice has evolved over this period. Current practice has moved away from clipping of aneurysms and towards coil embolisation performed by interventional radiologists. Electrode stimulation of deep brain regions for movement disorders is the current practice, whereas 10 years ago the same disorders were dealt with by lesioning of the relevant regions. In spinal neurosurgery, instrumentation is increasingly favoured currently. In the field of neuro-oncology, current practice favours minimal access to the target area by the use of stereotactic localisation. CONCLUSIONS Changes were most pronounced in the subspecialties of vascular, functional and spinal neurosurgery within this 10-year period. Knowledge of such dynamics is valuable in health resource management as well as planning for neurosurgical training programmes. PMID:18765031

  8. HIV-positive shopper who bit employee gets 10 years in jail.

    Science.gov (United States)

    1996-05-31

    Judge John Goshgarian sentenced John [name removed] to 10 years in prison for biting a store employee and then declaring he was HIV-positive. An unidentified employee at the Sam's Club store in Gurnee, IL tried to block [name removed] from exiting during questioning about a check he had just written. The bite [name removed] made on the employee's arm left teeth marks and drew blood. [Name removed] was charged with criminal transmission of HIV, a charge rarely used. He pled guilty to a lesser offense-aggravated battery in a public way, as well as related charges of forgery, possession of a fictitious driver's license, and obstruction of justice. The judge sentenced [name removed] to the maximum of 10 years in prison on the battery charge; criminal transmission punishment is 3 to 7 years in prison. [Name removed]'s test results remain sealed, although the store employee has been notified of the results and is undergoing monthly testing for HIV antibodies. Thus far, the results show he does not have the virus.

  9. 100% Retention of Snowpack Derived Nitrogen Over 10 Years in High Arctic Tundra

    Science.gov (United States)

    Choudhary, S.; Tye, A. M.; Young, S. D.; West, H. M.; Phoenix, G. K.

    2013-12-01

    Tundra ecosystems are susceptible to atmospheric nitrogen (N) deposition, increasing as a result of anthropogenic activities as well as climate change. Depositions that get accumulated within the snowpack during winter months are released in spring during snowmelt, providing a periodic input of reactive N in the melt water to such nutrient limited ecosystems. Identifying ecosystem N retention and allocation and how this change over time is important to understanding the long-term consequences of such N depositions to these ecosystems. We reanalysed 10 years later an atmospheric N deposition study established in Svalbard that in 2001 used 15N isotope tracers to determine the fate of N released from melting snowpack. Applications of 15N (99 atom%) at 0.1 and 0.5 g N m-2 were made immediately after snowmelt in 2001 as either Na15NO3 or 15NH4Cl. These applications were approximately 1 × and 5 × the yearly atmospheric deposition rates. In both the previous short-term (one week to two years after 15N tracer application) and our long-term re-sampling (10 years after 15N tracer application), ~67% of the total applied 15N was retained in the ecosystem, irrespective of the N forms or N dose. This meant the tundra had 100% long-term N retention after initial partitioning, suggesting a highly conservative N cycling. Bryophytes, followed by the organic soil horizon and then the microbial biomass formed the greatest short-term 15N sink. Maximum changes in 15N retention from the short- to long-term were observed in the microbial 15N pools, with ~75% of the 15N in soil located in its biomass during the initial partitioning (July 2001) decreasing to ~17% 10 years later. This indicates significant microbial N turnover mostly into stable humus N. In contrast, vascular plants, particularly Salix polaris, showed significant increases (~60%) in their 15N retention after 10 years, indicating a high capacity for acting as a long-term N sink in this tundra ecosystem. Because the largest

  10. Neural substrates of the development of cognitive control in children ages 5-10 years.

    Science.gov (United States)

    Sheridan, Margaret; Kharitonova, Maria; Martin, Rebecca E; Chatterjee, Aparna; Gabrieli, John D E

    2014-08-01

    Cognitive conflict detection and resolution develops with age across childhood and likely supports age-related increases in other aspects of cognitive and emotional development. Little is known about the neural correlates of conflict detection and resolution in early childhood. In the current study, we investigated age-related change in neural recruitment during a blocked spatial-incompatibility task (Simon task) in children ages 5-10 years using fMRI. Cortical thickness was measured using structural MRI. Across all children, there was greater activation in right prefrontal and bilateral parietal cortices for incompatible than compatible conditions. In older children, compared with younger children, there was decreased activation and decreased gray matter thickness in the medial PFC. Thickness and activation changes across age were associated within participants, such that thinner cortex was associated with less activation in the rostral ACC. These findings suggest that developmental change in medial PFC activation supports performance on cognitive control tasks in early childhood.

  11. PERFORATION OF A DUODENAL ULCER IN A 10 YEAR OLD BOY: A CASE REPORT

    Directory of Open Access Journals (Sweden)

    Prasenjit

    2014-04-01

    Full Text Available In this modern era of medicine, perforation of duodenal or gastric ulcer in pediatric patients is very rare. Here we are presenting a 10 year boy presented in emergency department of our rural tertiary care hospital with complaints of diffuse abdominal pain, nausea, vomiting of 36 hours and mild fever of 12 hours duration. O/E he had tachycardia, raised temperature, generalized abdominal tenderness, guarding, rigidity and rebound tenderness. On chest x-ray, free gas under diaphragm was seen. He had undergone exploratory laparotomy showing perforation at the 1st part of duodenum which was repaired by Graham’s patch repair. Post-operative recovery was uneventful. We suggested Helicobacter pylori workup on discharge but patient didn’t turn up in follow up.

  12. Health Care Finance Executive Personalities Revisited: A 10-Year Follow-up Study.

    Science.gov (United States)

    Lieneck, Cristian; Nowicki, Michael

    2015-01-01

    A dynamic health care industry continues to call upon health care leaders to possess not one but multiple competencies. Inherent personality characteristics of leaders often play a major role in personal as well as organizational success to include those in health care finance positions of responsibility. A replication study was conducted to determine the Myers-Briggs personality-type differences between practicing health care finance professionals in 2014, as compared with a previous 2003 study. Results indicate a significant shift between both independent samples of health care finance professionals over the 10-year period from original high levels of introversion to that of extraversion, as well as higher sensing personality preferences, as compared with the original sample's high level of intuition preferences. Further investigation into the evolving role of the health care finance manager is suggested, while continued alignment of inherent, personal characteristics is suggested to meet ongoing changes in the industry.

  13. Dental caries and treatment needs of children (6-10 years in rural Udaipur, Rajasthan

    Directory of Open Access Journals (Sweden)

    Dhar Vineet

    2009-01-01

    Full Text Available Objective : This study was done to examine caries prevalence and corresponding treatment needs in school children of rural areas of Udaipur, Rajasthan. Materials and Methods : A total of 750 children of rural areas in the age group of 6-10 years were examined, using WHO index, to record the prevalence of dental caries and treatment needs. The results were subjected to statistical analysis using chi square test. Results : Dental caries was found in 63.20% children, and 85.07% children needed dental treatment. The highest need was of one surface filling (85.73% followed by sealant (51.20%. Conclusion : Dental caries showed to be a significant health issue in the rural population requiring immediate attention.

  14. Intercostal myositis ossificans misdiagnosed as osteosarcoma in a 10-year-old child

    Energy Technology Data Exchange (ETDEWEB)

    Koob, Meriam; Durckel, Jean; Dosch, Jean-Claude; Dietemann, Jean-Louis [Hopital de Hautepierre, Service de Radiologie II, Hopitaux Universitaires, Strasbourg Cedex (France); Entz-Werle, Natacha [Hopitaux Universitaires, Hopital de Hautepierre, Service d' Onco-hematologie pediatrique, Strasbourg Cedex (France)

    2010-12-15

    Myositis ossificans (MO) is a rare benign cause of heterotopic bone formation within soft tissue. It most commonly affects adolescents and young adults, typically in the limbs and following trauma. Very few cases have been reported in children. We report here a case of nontraumatic MO occurring in a 10-year-old girl with an uncommon location in the 5th right intercostal space; it was initially misdiagnosed and treated as osteosarcoma. Imaging findings including plain radiographs, CT, MRI, bone scintigraphy and PET-CT are described. This case highlights the central role played by imaging in diagnosis, thus avoiding biopsy that can erroneously suggest osteosarcoma as the diagnosis, as occurred in this case. (orig.)

  15. Corneal cross-linking in a 10-year-old child with stage III keratoconus.

    Science.gov (United States)

    Abbondanza, Marco; Felice, Valentina De; Abbondanza, Gabriele

    2016-07-01

    Keratoconus is a corneal dystrophy characterized by progressive thinning, conical shape of the cornea and irregular astigmatism. It is particularly insidious when it occurs in very young patients. We report the case of a 10-year-old child with an aggressive stage III keratoconus, who was suggested to undergo a Penetrating Keratoplasty. We performed Corneal Collagen Cross-linking with epithelium removal instead, which was successful in arresting the rapid progression of keratoconus. Eighteen months later, Kmax had decreased by 1.3 D, astigmatism by 0.8 D, thinnest pachimetry had improved by 69 μm and CDVA was 20/32. This case confirms that Corneal Collagen Cross-linking is a safe and effective procedure for the treatment of keratoconus even in its aggressive forms. We encourage ophthalmic surgeons to favor conservative treatments when dealing with very young patients. © NEPjOPH.

  16. The paediatric flat foot and general anthropometry in 140 Australian school children aged 7 - 10 years

    Directory of Open Access Journals (Sweden)

    Evans Angela M

    2011-04-01

    Full Text Available Abstract Background Many studies have found a positive relationship between increased body weight and flat foot posture in children. Methods From a study population of 140 children aged seven to 10 years, a sample of 31 children with flat feet was identified by screening with the FPI-6. Basic anthropometric measures were compared between subjects with and without flat feet as designated. Results The results of this study, in contrast to many others, question the association of flat feet and heavy children. A significant relationship between foot posture and weight (FPI (L r = -0.186 (p Conclusions This study presents results which conflict with those of many previous investigations addressing the relationship between children's weight and foot posture. In contrast to previous studies, the implication of these results is that heavy children have less flat feet. Further investigation is warranted using a standardized approach to assessment and a larger sample of children to test this apparent contradiction.

  17. Event related potentials in anemic school--going girls of age group 8 to 10 years.

    Science.gov (United States)

    Bandhu, R; Shankar, N; Tandon, O P; Madan, N

    2011-01-01

    In the present study the effects of anemia on cognitive functions were studied in school going girls aged 8-10 years. The cognitive functions were assessed by Event Related Potentials (P300) and by the psychometric tests, i.e., Raven's progressive matrices test and Digit span attention test. The girls with Hb 12 g/dl into control group. Hematological values of the control group were significantly better than anemic group. P300 latency in the anemic girls was delayed as compared to control group but, no statistically significant difference was observed for P300 latency and P300 amplitude between the control group and the anemic group. The psychometric test scores for intelligence quotient and transformed quotient were also better but not statistically significant in control group of girls as compared to anemic girls. However, the hematocrit values showed a significant correlation with the P300 wave latency showing that the hematological status is associated with some effects on cognition.

  18. Tibial nerve intraneural ganglion cyst in a 10-year-old boy

    Energy Technology Data Exchange (ETDEWEB)

    Squires, Judy H. [University of Cincinnati College of Medicine, Department of Radiology, Cincinnati, OH (United States); Emery, Kathleen H.; Johnson, Neil [Cincinnati Children' s Hospital Medical Center, Division of Radiology, Cincinnati, OH (United States); Sorger, Joel [Cincinnati Children' s Hospital Medical Center, Division of Orthopedics, Cincinnati, OH (United States)

    2014-04-15

    Intraneural ganglion cysts are uncommon cystic lesions of peripheral nerves that are typically encountered in adults. In the lower extremity, the peroneal nerve is most frequently affected with involvement of the tibial nerve much less common. This article describes a tibial intraneural ganglion cyst in a 10-year-old boy. Although extremely rare, intraneural ganglion cysts of the tibial nerve should be considered when a nonenhancing cystic structure with intra-articular extension is identified along the course of the nerve. This report also details the unsuccessful attempt at percutaneous treatment with US-guided cyst aspiration and steroid injection, an option recently reported as a viable alternative to open surgical resection. (orig.)

  19. A large tumour of the left atrium – A 10-year follow-up

    Directory of Open Access Journals (Sweden)

    Agnieszka M. Łebek-Szatańska

    2016-11-01

    Full Text Available Benign myxomas are the most common primary tumors in the left atrium of the heart, and they usually require urgent operative management. However, with the constant aging of the population and treatment of patients with severe concomitant diseases, an interesting question is the efficacy of the conservative approach. We present a case of a 75-year-old woman who was previously diagnosed with a left atrial myxoma, underwent an operation to resect it and then developed a recurrent tumor at the site of resection, which was found by control echocardiography 1.5 years later. She has been observed for over 10 years, as she repeatedly refused reoperation. In the setting of this example of a relatively favorable clinical course of left atrium myxoma, we discuss the current knowledge about the natural history of these tumors and the role of echocardiography in predicting their growth and complications.

  20. Maturogenesis of Two Maxillary Central Incisors: A Case Report with 10 Years of Follow Up

    Directory of Open Access Journals (Sweden)

    Abdollah Ghorbanzadeh

    2015-10-01

    Full Text Available This case report describes the treatment of two immature maxillary central incisors in a 7- year-old female patient. She suffered complicated crown fracture because of trauma, and the root formation was incomplete. White mineral trioxide aggregate (MTA was selected as the pulp-capping material after cervical pulpotomy to preserve the pulp tissue vitality and achieve maturogenesis. Follow-up evaluations showed successful treatment in terms of preservation of pulp vitality and demonstrated marked continuous physiological root devel- opment. During 10 years of follow-up, both teeth were clinically asymptomatic, and radio- graphic evaluations showed apparent root regeneration with apical root-end closure without pulp or periapical pathosis.

  1. Use of Qualitative Methods in Published Health Services and Management Research: A 10-Year Review

    Science.gov (United States)

    Weiner, Bryan J.; Amick, Halle R.; Lund, Jennifer L.; Lee, Shoou-Yih Daniel; Hoff, Timothy J.

    2011-01-01

    Over the past 10 years, the field of health services and management research has seen renewed interest in the use of qualitative research methods. This article examines the volume and characteristics of qualitative research articles published in nine major health services and management journals between 1998 and 2008. Qualitative research articles comprise 9% of research articles published in these journals. Although the publication rate of qualitative research articles has not kept pace with that of quantitative research articles, citation analysis suggests that qualitative research articles contribute comparably to the field’s knowledge base. A wide range of policy and management topics has been examined using qualitative methods. Case study designs, interviews, and documentary sources were the most frequently used methods. Half of qualitative research articles provided little or no detail about key aspects the study’s methods. Implications are discussed and recommendations are offered for promoting the publication of qualitative research. PMID:20675353

  2. School children's responses on a semantic differential over a 10-year span.

    Science.gov (United States)

    Helwig, Andrew A; Avitable, Nanci

    2004-08-01

    A semantic differential scale was administered to 208 school children when they were in the second, fourth, sixth, eighth, tenth, and twelfth grades. Their perceptions towards two concepts were measured, Education (going to school) and Work (having a job). Each semantic differential scale had 15 adjective pairs and reflected the three underlying factors of Evaluative, Potency, and Activity. Because the study was conducted for 10 years (ages seven to 18), the changing cognitive developmental stages of the children were expected to influence factor analytic and reliability results. Confirmatory factor analysis, which forced the data into three factors, did not clearly identify the expected three factors, although more items loaded on the three factors with age. An exploratory factor analysis identified a trend across grades from six to four factors over time. Reliability also improved across age groups. Caution should be exercised when using the semantic differential with young children in investigations of abstract concepts.

  3. Acute Cholangitis following Intraductal Migration of Surgical Clips 10 Years after Laparoscopic Cholecystectomy

    Directory of Open Access Journals (Sweden)

    Natalie E. Cookson

    2015-01-01

    Full Text Available Background. Laparoscopic cholecystectomy represents the gold standard approach for treatment of symptomatic gallstones. Surgery-associated complications include bleeding, bile duct injury, and retained stones. Migration of surgical clips after cholecystectomy is a rare complication and may result in gallstone formation “clip cholelithiasis”. Case Report. We report a case of a 55-year-old female patient who presented with right upper quadrant pain and severe sepsis having undergone an uncomplicated laparoscopic cholecystectomy 10 years earlier. Computed tomography (CT imaging revealed hyperdense material in the common bile duct (CBD compatible with retained calculus. Endoscopic retrograde cholangiopancreatography (ERCP revealed appearances in keeping with a migrated surgical clip within the CBD. Balloon trawl successfully extracted this, alleviating the patient’s jaundice and sepsis. Conclusion. Intraductal clip migration is a rarely encountered complication after laparoscopic cholecystectomy which may lead to choledocholithiasis. Appropriate management requires timely identification and ERCP.

  4. Voice disorders without organic diseases of the larynx. A 10-year review of 62 patients.

    Science.gov (United States)

    Watanabe, Y; Miura, M; Shoji, H

    1983-01-01

    We reviewed the clinical records of 62 patients with voice disorders without organic diseases of the larynx who were examined in the Department of Otolaryngology, Kurume University Hospital during the 10 years from 1971 to 1980. There were 9 patients with psychogenic dysphonia, 24 with vocal abuse, 4 with spastic dysphonia, 9 with mutational voice disturbance, 8 with virilization of voice, 7 with dysphonia attributed to diseases of other organs than the larynx, and 1 with senile change of voice. The clinical service to the patients with these kinds of dysphonia has been poor in Japan for lack of trained voice pathologists. This has been also the case with our department. Recognition for the necessity of voice pathologists is strongly demanded.

  5. Prevalence of intestinal parasitic infections in Jenin Governorate, Palestine:a 10-year retrospective study

    Institute of Scientific and Technical Information of China (English)

    Sami Bdir; Ghaleb Adwan

    2010-01-01

    Objective:To assess the prevalence of intestinal parasites among Jenin Governorate (Northern Palestine) population.Methods:A retrospective laboratory analysis of stool specimens was carried out for intestinal parasite examination in Jenin Governmental Hospital, Jenin Governorate, Northern Palestine. The records were collected from the clinical microbiology laboratory of the Jenin Governmental Hospital between January2000and December2009. Results: Our retrospective study showed that the prevalence of intestinal parasite infection during10 years ranged from32.0-41.5%. There are at least7 different parasitesencountered. The most common pathogenic parasites identified were:Entamoeba histolytica(8.2-18.2%),Enterobius vermicularis(15.6-28.9%). The other parasites present wereGiardia lamblia, Ascaris lumbricoides, Strongyloides stercoralis,Taenia species andAncylostoma duodenale (Hookworms).Conclusions:Intestinal parasitic infection is an important public health problem in Jenin governorate, Palestine. It is necessary to develop effective prevention and control strategies including health education and environmental sanitation improvement.

  6. Fitness and Health Effects of Frequent Intense Training in 8-10-Year Old Danish Children

    DEFF Research Database (Denmark)

    Larsen, Malte Nejst

    Physical activity for children has been much debated in recent years. Everyone has seemed to agree that it is important for children to exercise for the sake of physiological health, but cognitive functions and psycho-social behaviour are now also considered to be affected by physical activity. I...... other aspects of using small sided ball games in schools as part of physical education.......) compared to children active in other sports. Paper III and IV described the long-term training effects of frequent intense small-sided ball games (SSG), interval running (IT) and circuit strength training (CST) for 8-10-year-old school children. Analysis of baseline-to-10-months change scores showed...

  7. Prevalence of neonatal hypothyroidism and phenylketonuria in Southern Thailand: A 10-year report

    Directory of Open Access Journals (Sweden)

    Yavamal Sutivijit

    2011-01-01

    Full Text Available Background: Congenital hypothyroidism and phenylketonuria, the two major problems of several metabolic errors are presently the focus of attention, in Thailand. These two conditions are assigned as diseases to be controlled under the National Public Health Policies of Thailand. Materials and Methods: Here, the authors summarize and report the 10-year study on the prevalence of neonatal hypothyroidism and phenylketonuria in Southern Thailand. Results: This report is good representative data from Thailand, a country in Southeast Asia. Another interesting point in this study is the concern of the recalling process. Conclusion: It can be seen that there are a considerable number of infants who did not receive the confirmation test due to loss of follow-up after calling for a recheck.

  8. From Exotic to Mainstream: A 10-year Odyssey from Internet Speed to Boundary Spanning with Scrum

    Science.gov (United States)

    Baskerville, Richard; Pries-Heje, Jan; Madsen, Sabine

    Based on four empirical studies conducted over a 10-year time period from 1999 to 2008 we investigate how local software processes interact with global changes in the software development context. In 1999 companies were developing software at high speed in a desperate rush to be first-to-market. In 2001 a new high speed/quick results development process had become established practice. In 2003 changes in the market created the need for a more balanced view on speed and quality, and in 2008 companies were successfully combining agile and plan driven approaches to achieve the benefits of both. The studies reveal a twostage pattern in which dramatic changes in the market causes disruption of established practices, experimentation, and process adaptations followed by consolidation of lessons learnt into a new (and once again mature) software development process. Limitations, implications, and areas for future research are discussed.

  9. Features of the psycho-physiological status of boys in 9-10 years.

    Directory of Open Access Journals (Sweden)

    Romanenko V.A.

    2012-08-01

    Full Text Available The problems of diagnosis of psycho-physiological status of boys in the prepubertal stage of their biological development is considered. The study involved 94 boys aged 9-10 years. They were assessed by parameters of physical development, the functional state of the nervous, cardio-respiratory, muscular and sensory systems and motor fitness, energy and properties of psychodynamics. It is shown that the failure of the approach to assess children's physical health on the grounds of their physical development. Children of this age are characterized by a lag in terms of static lung volume, and vice versa - ahead of age norms in the development of pulmonary ventilation function and resistance to hypoxia. Central hemodynamic parameters vary within age norms. From the observed dominance of neurodynamic mechanisms of excitation and response of advanced type. The established features of the psycho-physiological status, can be used as prognostic indicators in guiding children to sports activities.

  10. Inter-comparison of 10-year precipitation simulated by several RCMs for Asia

    Science.gov (United States)

    Feng, Jinming; Fu, Congbin

    2006-12-01

    In phase II of the Regional Climate Model Inter-comparison Project (RMIP) for Asia, the regional climate has been simulated for July 1988 through December 1998 by five regional climate models and one global variable resolution model. Comparison of the 10-year simulated precipitation with the observations was carried out. The results show that most models have the capacity to reproduce the basic spatial pattern of precipitation for Asia, and the main rainbelt can be reproduced by most models, but there are distinctions in the location and the intensity. Most models overestimate the precipitation over most continental regions. Interannual variability of the precipitation can also be basically simulated, while differences exist between various models and the observations. The biases in the stream field are important reasons behind the simulation errors of the Regional Climate Models (RCMs). The cumulus scheme and land surface process have large influences on the precipitation simulation. Generally, the Grell cumulus scheme produces more precipitation than the Kuo scheme.

  11. A case of choroidal osteoma in a 10-year-old child

    Directory of Open Access Journals (Sweden)

    Behera M

    2015-11-01

    Full Text Available Madhusmita Behera,1 Manmath Kumar Das2 1Rotary Narayana Nethralaya, Kolkata, India; 2Vitreo-Retina Services, CL Gupta Eye Institute, Moradabad, India Abstract: Choroidal osteoma is a rare, benign tumor, usually diagnosed in healthy adult women in their second or third decade of life. Though its etiology and pathogenesis are unclear, it is usually diagnosed due to its typical clinical features of yellowish-orange colored subretinal lesion at posterior pole and a dense echogenic plaque persisting even in lower gains on B-scan ultrasonography. Mostly unilateral (79%, the median age of diagnosis is 26 years. It is relatively rare in children. We report a case of choroidal osteoma in a 10-year-old boy. Keywords: choroidal osteoma, choroidal osseous choristoma, choroidal tumor

  12. Occupational therapy and the journal citation reports: 10-year performance trajectories.

    Science.gov (United States)

    Holguin, Jess Anthony

    2009-01-01

    The purpose of this study was to document performance of occupational therapy journals on the metrics of the Journal Citation Reports (JCR), the annually appearing index used as a yardstick to assess the quality of scholarly publications. Outcomes for the field's two indexed journals, the American Journal of Occupational Therapy and OTJR: Occupation, Participation and Health, were assessed over a 10-year period (1996-2005) to determine their overall standing and patterns of change on each of the JCR's five metrics. The mean category ranking for the two journals was generally above the 50th percentile. However, they performed least adequately and evidenced a downward trend over time on the most widely used metric (the journal impact factor). Possible reasons underlying this latter result are explored, pressing implications of the overall findings for practice and research are discussed, and strategic steps toward ethically safeguarding the profession's viability are offered.

  13. Nitrogen containing bisphosphonates associated osteonecrosis of the jaws: A review for past 10 year literature

    Directory of Open Access Journals (Sweden)

    Vijay Kumar

    2014-01-01

    Full Text Available Nitrogen containing bisphosphonate (N-BP therapy is used extensively to treat osteoporosis and osteolytic bone lesions. Recently, a special form of osteonecrosis limited to the maxillofacial skeleton has been discovered especially within those patients who are receiving either long-term N-BP therapy alone and/or associated with invasive dental procedure. Bisphosphonates accumulate almost exclusively in maxillofacial skeleton owing to high bone turn over remodeling to maintain the mechanical competence. The pathogenesis and why it commonly appears in maxillofacial skeleton and the fixed treatment strategies remains unknown. The aim of this study was to improve the clinician understanding of N-BPs associated osteonecrosis of maxillofacial skeleton by reviewing the past 10 year literature.

  14. Nitrogen containing bisphosphonates associated osteonecrosis of the jaws: A review for past 10 year literature

    Science.gov (United States)

    Kumar, Vijay; Shahi, Ashish Kumar

    2014-01-01

    Nitrogen containing bisphosphonate (N-BP) therapy is used extensively to treat osteoporosis and osteolytic bone lesions. Recently, a special form of osteonecrosis limited to the maxillofacial skeleton has been discovered especially within those patients who are receiving either long-term N-BP therapy alone and/or associated with invasive dental procedure. Bisphosphonates accumulate almost exclusively in maxillofacial skeleton owing to high bone turn over remodeling to maintain the mechanical competence. The pathogenesis and why it commonly appears in maxillofacial skeleton and the fixed treatment strategies remains unknown. The aim of this study was to improve the clinician understanding of N-BPs associated osteonecrosis of maxillofacial skeleton by reviewing the past 10 year literature. PMID:24932183

  15. Inter-Comparison of 10-year Precipitation Simulated by Several RCMs for Asia

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    In phase Ⅱ of the Regional Climate Model Inter-comparison Project (RMIP) for Asia, the regional climate has been simulated for July 1988 through December 1998 by five regional climate models and one global variable resolution model. Comparison of the 10-year simulated precipitation with the observations was carried out. The results show that most models have the capacity to reproduce the basic spatial pattern of precipitation for Asia, and the main rainbelt can be reproduced by most models, but there are distinctions in the location and the intensity. Most models overestimate the precipitation over most continental regions. Interannual variability of the precipitation can also be basically simulated, while differences exist between various models and the observations. The biases in the stream field are important reasons behind the simulation errors of the Regional Climate Models (RCMs). The cumulus scheme and land surface process have large influences on the precipitation simulation. Generally, the Grell cumulus scheme produces more precipitation than the Kuo scheme.

  16. Kinematic characteristics of the ski jump inrun: a 10-year longitudinal study.

    Science.gov (United States)

    Janura, Miroslav; Cabell, Lee; Elfmark, Milan; Vaverka, Frantisek

    2010-05-01

    The athlete's inrun position affects the outcome for take-off in ski jumping. The purpose of this study was to examine the kinematic parameters between skiers' adjacent body segments during their first straight path of the inrun. Elite ski jumpers participated in the study at the World Cup events in Innsbruck, Austria, during the years 1992 through 2001. A video image was taken at a right angle to the tracks of the K-110 (meter) jumping hill. Kinematic data were collected from the lower extremities and trunk of the athletes. Findings indicated that jumpers had diminished ankle and knee joint angles and increased trunk and hip angles over the 10 years. In recent years, the best athletes achieved a further length of their jumps, while they experienced slower inrun average velocity. These results are perhaps explained by several possible contributing factors, such as new technique of the jumper's body kinematics, advancements in equipment technology, and somatotype of the jumpers.

  17. Parkin disease in a Brazilian kindred: Manifesting heterozygotes and clinical follow-up over 10 years.

    Science.gov (United States)

    Khan, Naheed L; Horta, Wagner; Eunson, Louise; Graham, Elizabeth; Johnson, Janel O; Chang, Shannon; Davis, Mary; Singleton, Andrew; Wood, Nicholas W; Lees, Andrew J

    2005-04-01

    We report on a large Brazilian kindred with young-onset parkinsonism due to either a homozygous or heterozygous mutation in parkin. A total of 6 members were affected: 5 were homozygous and 1 heterozygous for a deletion in exon 4. Two other heterozygotes also had extrapyramidal signs. All affected subjects showed characteristic features of parkin disease with foot dystonia and an excellent response to levodopa complicated by motor fluctuations and dyskinesia within 3 years of therapy. Careful clinical follow-up over 10 years showed the phenotype was similar in all the homozygotes with asymmetrical limb bradykinesia and early walking difficulties. Some acceleration of disability was observed in some of the cases as they entered the third decade of illness, but dementia was absent.

  18. Prevalence of Generalised Joint Hypermobility, Artralgia and Motor Competence in 10-year old school children

    DEFF Research Database (Denmark)

    Remvig, Lars; Kümmel, Christina; Halkjær-Kristensen, Jens

    2011-01-01

    Objectives: Diverging results exist for children regarding the relation between generalized joint hypermobility (GJH) and musculoskeletal complaints, as well as relations between GJH and insufficient motor development, and/or reduced physical activity level. The main purposes were to (1) survey...... the prevalence of GJH and of benign joint hypermobility syndrome (BJHS) in 10-year-old children, (2) compare children with and without GJH and BJHS regarding motor competence, physical activity, and musculoskeletal pain and injuries. Subjects and methods: All fourth-grade children in a Copenhagen municipality...... were invited to be clinically examined and tested for motor competence, and to answer a questionnaire about musculoskeletal pain, injuries, and physical activity. Results: The final cohort comprised 315 Caucasian children, 50.5% girls and 54% boys. GJH prevalence was 35.6, 16.8, or 11.1%, depending...

  19. Use of qualitative methods in published health services and management research: a 10-year review.

    Science.gov (United States)

    Weiner, Bryan J; Amick, Halle R; Lund, Jennifer L; Lee, Shoou-Yih Daniel; Hoff, Timothy J

    2011-02-01

    Over the past 10 years, the field of health services and management research has seen renewed interest in the use of qualitative research methods. This article examines the volume and characteristics of qualitative research articles published in nine major health services and management journals between 1998 and 2008. Qualitative research articles comprise 9% of research articles published in these journals. Although the publication rate of qualitative research articles has not kept pace with that of quantitative research articles, citation analysis suggests that qualitative research articles contribute comparably to the field's knowledge base. A wide range of policy and management topics has been examined using qualitative methods. Case study designs, interviews, and documentary sources were the most frequently used methods. Half of qualitative research articles provided little or no detail about key aspects the study's methods. Implications are discussed and recommendations are offered for promoting the publication of qualitative research.

  20. Blood pressure and 10-year mortality risk in the Milan Geriatrics 75+ Cohort Study

    DEFF Research Database (Denmark)

    Ogliari, Giulia; Westendorp, Rudi G J; Muller, Majon

    2015-01-01

    75+ Cohort Study. SUBJECTS: one thousand five hundred and eighty-seven outpatients aged 75 years and over. METHODS: the relations of systolic (SBP) and diastolic blood pressure (DBP) with mortality risk were analysed using Cox proportional hazards models. Blood pressure, Mini-Mental State Examination...... (MMSE) and Basic Activities of Daily Living (ADL) were assessed at baseline. All analyses were adjusted for socio-demographic factors, co-morbidities and medications. RESULTS: one thousand and forty-six patients died during 10-year follow-up. The relationships of SBP and DBP with mortality risk were U......-shaped; SBP of 165 mmHg and DBP of 85 mmHg were associated with the lowest mortality. Patients with SBP 60) higher mortality risk than patients with SBP 160-179 mmHg (P values 0...

  1. [Research progress of acupuncture for cerebral ischemia reperfusion injury in recent 10 years].

    Science.gov (United States)

    Yang, Yang; Sun, Hua

    2015-07-01

    By searching relevant data from the PubMed database, Chinese National Knowledge Infrastructure (CNKI) database and Wanfang database, a comprehensive analysis and review regarding acupuncture for cerebral ischemia reperfusion injury (CIRI) in recent 10 years were performed. The results showed that acupuncture could inhibit the inflammatory reaction, reduce oxidative stress injury, restrain brain edema formation, inhibit apoptosis, promote neural and vascular regeneration, etc. Acupuncture methods used included electroacupuncture, scalp acupuncture, eye acupuncture and "consciousness-restoring resuscitation needling", etc. The existing problem was that the intervention action of acupuncture was mainly focused on inhibiting inflammatory reaction and oxidative stress injury, and the study on apoptosis and neural and vascular regeneration was needed. It is suggested that from the aspect of multiple target points, the intervention mechanism of acupuncture for CIRI should be systemically studied in the future, which could provide new idea for clinical diagnosis and treatment on ischemic cerebrovascular diseases.

  2. The Effects of Lack of Joint Goal Planning on Divorce over 10 Years.

    Science.gov (United States)

    Gere, Judith; Almeida, David M; Martire, Lynn M

    Given the negative consequences of divorce on health and well-being, it is important to try to identify its predictors. In the current study we used data from the National Survey of Midlife Development (N = 2801) to examine the longitudinal effects of lack of joint goal planning with a romantic relationship partner on divorce over a 10-year period. Multilevel regression analyses showed that lack of joint planning with the relationship partner was associated with a 19% increase in the odds of divorce, even when controlling for various demographic (i.e., age, gender, relationship length, number of children in the household), individual (i.e., neuroticism, positive affect, negative affect, physical symptoms, planning), and relationship (i.e., marital empathy, partner strain, partner disagreement, marital satisfaction, commitment). These results demonstrate the importance of considering one's partner when making decisions and plans for the future, given that it has clear implications for relationship dissolution.

  3. Invasive pulmonary aspergillosis 10 years post bone marrow transplantation: a case report

    Directory of Open Access Journals (Sweden)

    Rashid Rifat

    2009-01-01

    Full Text Available Abstract Introduction Invasive pulmonary aspergillosis is a leading cause of mortality and morbidity in bone marrow transplant recipients. Establishing the diagnosis remains a challenge for clinicians working in acute care setting. However, prompt diagnosis and treatment can lead to favourable outcomes Case presentation We report a case of invasive aspergillosis occurring in a 39-year-old Caucasian female 10 years after an allogeneic haematopoietic bone marrow transplant, and 5 years after stopping all immunosuppression. Possible risk factors include bronchiolitis obliterans and exposure to building dust (for example, handling her husband's dusty overalls. There are no similar case reports in the literature at this time. Conclusion High clinical suspicion, especially in the setting of failure to respond to broad-spectrum antibiotics, should alert clinicians to the possibility of invasive pulmonary aspergillosis, which, in this case, responded to antifungal therapy.

  4. Epidemiological, Clinical and Paraclinical Study of Hydatid Cysts in Three Educational Medical Centers in 10 Years

    Directory of Open Access Journals (Sweden)

    Simindokht Shoaee

    2016-01-01

    Full Text Available Background: Echinococcosis or hydatidosis, caused by the larval stage of Echinococcus granulosus (E. granulosus, is an important public health problem in many areas of the world  and  Iran is a country of endemic situation for hydatidosis In the present study, we evaluated epidemiological, complications and clinical characteristics of hydatidosis at three University Medical Centers in Tehran over a 10-year period.Materials and Methods: This is a descriptive cross-sectional study performed in patients with hydatid cysts. Information about age, gender, number of cysts, organ involvement, morbidity and mortality and relapse were collected from medical records of hydatid patients. Paraclinic information such as CT Scan, MRI, ultrasound, complete blood count, pathological diagnosis and complication of disease were collected.Results: Overall, 81 patients, 35 (43.2% male and 46 (56.8% female, who were diagnosed as having hydatid cyst by clinical and radiological findings, with pathologic documentation were studied in three university medical center registries over a 10-year period (2003- 2012 in Tehran. Fourteen patients (17% of cases had complications resulting from this disease. Patients' age ranged from 5 to 86 years, and the peak prevalence of the disease was between 20 and 40 (34% of cases.Conclusion: Iran  is a country of endemic situation for hydatidosis. Prevalence rate of hydatidosis in Iran was reported to be 0.61-2 in 100000 populations. The highest  rate of infection and complications were in patients of 20-40 years age. Clinical examination revealed that abdominal pain was the most common complaint and was present in 51.7% of the cases. Other most common complain were cough, abdominal mass, dyspnea, icterus, chest pain, dyspepsia, back pain and seizure; and it was result of occupying effect of cysts in organs. This is similar with previous studies in Iran

  5. Evolution of Helicobacter pylori susceptibility to antibiotics during a 10-year period in Lithuania.

    Science.gov (United States)

    Kupcinskas, Limas; Rasmussen, Lone; Jonaitis, Laimas; Kiudelis, Gediminas; Jørgensen, Marianne; Urbonaviciene, Neringa; Tamosiunas, Vytas; Kupcinskas, Juozas; Miciuleviciene, Jolanta; Kadusevicius, Edmundas; Berg, Douglas; Andersen, Leif P

    2013-05-01

    The study evaluated the changes in the prevalence of Helicobacter pylori strains with primary resistance to antibiotics during the last 10 years in Lithuania. H. pylori susceptibilities to antibiotics were tested in 89 patients in 1998, in 81 patients in 2001 and in 90 patients in 2007/2008. Susceptibility to metronidazole, clarithromycin, amoxicillin and tetracycline was tested using E-test or agar dilution method. Susceptibility to ciprofloxacin was only tested in 2007/2008. Data about utilization of all authorized and available on market macrolides and clindamycin in Lithuania during 2003-2007 were evaluated using WHO ATC/DDD methodology. A total of 260 H. pylori strains cultured from untreated adult patients were investigated. Primary resistance rates (1998, 2001 and 2007/2008) for metronidazole were 24.7%, 33.3%, and 35.6%, for clarithromycin 1.1%, 3.7%, and 3.3% and for tetracycline 0%, 2.5% and 0% respectively. No cases of amoxicillin resistance have been detected. The resistance rate for ciprofloxacin was 5.6% in 2007/2008. Data of total macrolides and clarithromycin utilization in Lithuania revealed that despite an increase of consumption of these drugs in Lithuania during 2003-2007 in 1.5 times, the total macrolide consumption remains one of the lowest in Europe. We have not observed any significant changes in the susceptibility of H. pylori to the most widely used antibiotics during the recent 10-year period. The low resistance rate to clarithromycin might be related to the policy to avoid use of macrolides as first-line treatment for pulmonary and other infections.

  6. Lamont-Doherty's Secondary School Field Research Program: 10 years of field research-based education.

    Science.gov (United States)

    Newton, R.; Vincent, S.; Gribbin, S.; Peteet, D. M.; Sambrotto, R.; Bostick, B. C.; Corbett, E.; Nguyen, K.; Bjornton, J.; Lee, D.; Dubossi, D.; Reyes, N.

    2014-12-01

    This fall marks the 10th year in which we have run a research-project-based educational program for high school students and science teachers at the Lamont-Doherty Earth Observatory. This summer's cohort included 31 teenagers, 7 science teachers, and 16 college students, most of whom are returning to the program to help run the research projects. Nearly all of our students attend non-competitive-entry public schools in NYC or the neighborhoods around the Observatory. Over 80% are from under-served minority populations. Most receive Title I/III assistance. About 60% are young women. During the past 10 years, nearly all of our participants have gone on to 4-year colleges. About half are declaring science and engineering majors. Our students receive scholarship support at rates several times higher than their graduating peers, including 5 Gates Millennium scholars over the past 5 years. Our science is centered on studies of a nearby tidal wetland, where we have expanded from fish collections in year one to include everything from sediment core analysis to soil chemistry to nutrient cycles to the local food web. In this presentation we will look back over 10 years of experience and focus on what lessons can be learned about (1) how to engage teams of young investigators in authentic scientific research; (2) what cultural/organizational structures encourage them to make use of place- and project-based learning and (3) what the participants themselves report as the most useful aspects of our programming. The presentation will include video clips from the students' field experiences and from reflective interviews with "graduates".

  7. Incidence of Gallstone Formation and Cholecystectomy 10 Years After Bariatric Surgery.

    Science.gov (United States)

    Melmer, Andreas; Sturm, Wolfgang; Kuhnert, Bernhard; Engl-Prosch, Julia; Ress, Claudia; Tschoner, Alexander; Laimer, Markus; Laimer, Elisabeth; Biebl, Matthias; Pratschke, Johann; Tilg, Herbert; Ebenbichler, Christoph

    2015-07-01

    Rapid weight loss is a risk factor for gallstone formation, and postoperative treatment options for gallstone formation are still part of scientific discussion. No prospective studies monitored the incidence for gallstone formation and subsequent cholecystectomy after bariatric surgery longer than 5 years. The aim of the study was to determine the incidence of gallstone formation and cholecystectomy in bariatric patients over 10 years. One hundred nine patients were observed over 10 years after laparoscopic gastric banding or gastric bypass/gastric sleeve. The incidence of gallstone formation and cholecystectomy was correlated to longitudinal changes in anthropometric parameters. In total, 91 female and 18 male patients were examined. Nineteen patients had postoperative gallstone formation, and 12 female patients required cholecystectomy. The number needed to harm for gallstone formation was 7.1 and 2.3 cases in the banding group and gastric bypass/gastric sleeve group, respectively. The number needed to harm for cholecystectomy was 11.6 and 2.5 cases in the banding group and the gastric bypass/gastric sleeve group, respectively. Weight loss was higher in patients requiring subsequent cholecystectomy. Mean follow-up to cholecystectomy was 21.5 months with the latest operation after 51 months. Female gender and rapid weight loss were major risk factors for postoperative cholelithiasis. Ultrasound examinations within 2 to 5 years are recommended in every patient, independent of bariatric procedure. Pharmacologic treatment should be considered in high risk patients within 2 to 5 years to prevent postoperative cholelithiasis. This helps to optimize patient care and lowers postoperative morbidity.

  8. Prognostic Factors and Treatment Outcomes of Parotid Gland Cancer: A 10-Year Single-Center Experience.

    Science.gov (United States)

    Chang, Jae Won; Hong, Hyun Jun; Ban, Myung Jin; Shin, Yoo Seob; Kim, Won Shik; Koh, Yoon Woo; Choi, Eun Chang

    2015-12-01

    To investigate the treatment outcomes of parotid gland cancer at a single center over a 10-year period and to evaluate the prognostic significance of maximum standardized uptake value. Retrospective case series with chart review. Academic care center. Ninety-eight patients with primary parotid gland cancer who were surgically treated at Yonsei University Head & Neck Cancer Clinic between January 1999 and December 2008 were analyzed. Patient data were collected retrospectively from medical charts. The investigators analyzed the association of clinicopathological factors and maximum standardized uptake value on (18)F-fluorodeoxyglucose positron emission tomography-computed tomography scan with disease-specific survival. Mean patient age was 49.7 years. Mean follow-up was 48.8 months. Thirty-three, 40, 30, and 23 patients had stage I, II, III, and IVA disease, respectively. Mucoepidermoid carcinoma was the most common histologic type (34.7%), followed by acinic cell carcinoma (27.6%). Eighteen patients (18.4%) experienced recurrences (mean recurrence gap, 20.6 months; range, 2-87 months). Five- and 10-year disease-specific survival rates were 93.6% and 81.8%, respectively. In the univariate analysis, pathologic T stage, pathologic lymph node status, resection margin, external parenchymal extension, and maximum standardized uptake value were significantly associated with disease-specific survival. Pathologic lymph node status and maximum standardized uptake value were independent prognostic factors in the multivariate analysis. Our single-center experience with parotid gland cancer treatment is consistent with the literature. Cervical lymph node metastasis and high maximum standardized uptake value are associated with poor survival in parotid gland cancer. © American Academy of Otolaryngology—Head and Neck Surgery Foundation 2015.

  9. The endonasal microscopic approach for pituitary adenomas and other parasellar tumors: a 10-year experience.

    Science.gov (United States)

    Fatemi, Nasrin; Dusick, Joshua R; de Paiva Neto, Manoel A; Kelly, Daniel F

    2008-10-01

    THE DIRECT ENDONASAL transsphenoidal approach to the sella with the operating microscope was initially described more than 20 years ago. Herein, we describe the technique, its evolution, and lessons learned over a 10-year period for treating pituitary adenomas and other parasellar pathology. From July 1998 to January 2008, 812 patients underwent a total of 881 operations for a pituitary adenoma (n = 605), Rathke's cleft cyst (n = 59), craniopharyngioma (n = 26), parasellar meningioma (n = 23), chordoma (n = 18), or other pathological condition (n = 81). Of these, 118 operations (13%) included an extended approach to the suprasellar, infrasellar/clival, or cavernous sinus regions. Endoscopic assistance was used in 163 cases (19%) overall, including 36% of the last 200 cases in the series and 18 (72%) of the last 25 extended endonasal cases. Surgical complications included 19 postoperative cerebrospinal fluid leaks (2%), 6 postoperative hematomas (0.7%), 4 carotid artery injuries (0.4%), 4 new permanent neurological deficits (0.4%), 3 cases of bacterial meningitis (0.3%), and 2 deaths (0.2%). The overall complication rate was higher in the first 500 cases in the series and in extended approach cases. Major technical modifications over the 10-year period included increased use of shorter (60-70 mm) endonasal speculums for greater instrument maneuverability and visualization, the micro-Doppler probe for cavernous carotid artery localization, endoscopy for more panoramic visualization, and a graded cerebrospinal fluid leak repair protocol. These changes appear to have collectively and incrementally made the approach safer and more effective. In summary, the endonasal approach provides a minimally invasive route for removal of pituitary adenomas and other parasellar tumors.

  10. Neurocognition and Duration of Psychosis: A 10-year Follow-up of First-Episode Patients.

    Science.gov (United States)

    Rund, Bjørn Rishovd; Barder, Helene Eidsmo; Evensen, Julie; Haahr, Ulrik; ten Velden Hegelstad, Wenche; Joa, Inge; Johannessen, Jan Olav; Langeveld, Johannes; Larsen, Tor Ketil; Melle, Ingrid; Opjordsmoen, Stein; Røssberg, Jan Ivar; Simonsen, Erik; Sundet, Kjetil; Vaglum, Per; McGlashan, Thomas; Friis, Svein

    2016-01-01

    A substantial proportion of schizophrenia-spectrum patients exhibit a cognitive impairment at illness onset. However, the long-term course of neurocognition and a possible neurotoxic effect of time spent in active psychosis, is a topic of controversy. Furthermore, it is of importance to find out what predicts the long-term course of neurocognition. Duration of untreated psychosis (DUP), accumulated time in psychosis the first year after start of treatment, relapse rates and symptoms are potential predictors of the long-term course. In this study, 261 first-episode psychosis patients were assessed neuropsychologically on one or more occasions. Patients were tested after remission of psychotic symptoms and reassessed 1, 2, 5, and 10 years after inclusion. The neurocognitive battery consisted of California Verbal Learning Test, Wisconsin Card Sorting Test, Controlled Oral Word Association Task, Trail Making A and B, and Finger Tapping. We calculated a composite score by adding the z-scores of 4 tests that were only moderately inter-correlated, not including Finger Tapping. Data were analyzed by a linear mixed model. The composite score was stable over 10 years. No significant relationship between psychosis before (DUP) or after start of treatment and the composite score was found, providing no support for the neurotoxicity hypothesis, and indicating that psychosis before start of treatment has no significant impact on the course and outcome in psychosis. We found no association between symptoms and the neurocognitive trajectory. Stable remission during the first year predicted neurocognitive functioning, suggesting that the early clinical course is a good predictor for the long-term course. © The Author 2015. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  11. Injuries in a Professional Ballet Dance Company: A 10-year Retrospective Study.

    Science.gov (United States)

    Ramkumar, Prem N; Farber, Joseph; Arnouk, Johnny; Varner, Kevin E; Mcculloch, Patrick C

    2016-03-01

    Ballet dancers are high-performance athletes who are particularly susceptible to a wide variety of musculoskeletal injuries. However, they are relatively understudied, and data on their injury rates are lacking. This retrospective study features the largest aggregate data on professional ballet dancers to date and aims to identify the most common diagnoses and areas of injury in this unique population to better direct preventative and clinical practices. The study encompassed a 10-year period from January 2000 to December 2010 of dancers from a single company. Data regarding the dancers' age, gender, location of injury, and diagnosis were collected from workers' compensation claims, company records, and medical records maintained by the treating doctors. These were analyzed to determine metrics on injury incidence, frequency, and diagnosis. Over the 10-year span, 574 injuries occurred. There were approximately 52 dancers per year for a total of 153 who danced at least one complete season during the study period. The average age was 27, and 53% were female. Given turnover with retirement and replacements, the total number of dancer-years was 520, indicating an injury incidence per annum of 1.10 (574 injuries per 520 dancer-years). The most common locations of injury were foot and ankle and the lumbar spine, with the three most common diagnoses making up greater than a third (37%) of the total. As the current largest study in professional ballet, the findings set the benchmark metrics for musculoskeletal injury to the foot, ankle, and lumbar spine sites. Future studies should aim to identify injury risk factors and modalities for prevention of these injuries.

  12. The relationship between the type of destructive spondyloarthropathy and its 10 years ago cervical spine alignment.

    Science.gov (United States)

    Maruyama, Koji; Matsuyama, Yukihiro; Yanase, Makoto; Sakai, Yoshihito; Katayama, Yoshito; Imagama, Shiro; Ito, Zenya; Wakao, Norimitsu; Yukawa, Yasutsugu; Ito, Keigo; Kamiya, Mitsuhiro; Kanemura, Tokumi; Sato, Koji; Ishiguro, Naoki

    2009-06-01

    The objective of this retrospective study was to analyze the relationship between the type of destructive spondyloarthropathy (DSA) and its 10 years ago cervical spine alignment. DSA was reported as a serious complication of long-term hemodialysis. Although previous reports in regard to risk factor of DSA dealt with the period of hemodialysis and the patient's age upon commencement of hemodialysis, we could not find any reports of the relationship between the type of DSA and its 10 years ago cervical spine alignment. In 96 DSA patients who were the subjects of our study, 8 patients were defined as stage 1, 39 patients as stage 2, 5 patients as stage 3 type A, 11 patients as stage 3 type B, and 33 patients as stage 3 type D. The C2/C7 angle of stage 3 type B was statistically low. The number of the abnormal local cervical alignment was larger in stage 3 types A and B. Multivariate analysis revealed that the risk factors of stage 3 types A and B were the C2/C7 angle and the existence of local abnormal alignment. Fifty-four patients were symptomatic due to DSA and treated at our hospital. Forty-four patients were treated conservatively with medications, physiotherapy, or wearing cervical brace. Ten patients underwent surgical treatment. The loss of physiological lordosis of cervical spine promoted the progression of DSA. Furthermore, the number of the abnormalities of local cervical alignment was statistically larger in stage 3 types A and B; they were the crucial factor promoting the progression of DSA stage 3 types A and B.

  13. Cow-related trauma: a 10-year review of injuries admitted to a single institution.

    Science.gov (United States)

    Murphy, Colin G; McGuire, Ciara M; O'Malley, Natasha; Harrington, Paul

    2010-05-01

    Bovine-related injuries to farmers are common in rural communities. Many injuries are significant requiring hospital admission and surgery. We reviewed all cattle-related injuries admitted to a regional trauma centre over 10 years and detail the nature of the injuries. A retrospective review was undertaken, using hospital inpatient coding system (HIPE) to identify patients admitted following cow-related trauma for the last 10 years. From retrieved charts mechanism of injury was identified, demographics recorded and Injury Severity Score (ISS) and Trauma Injury Severity Score (TRISS) calculated based on the injuries sustained. 47 patients were identified, with a median age of 53 years. 4 injuries occurred in children, and 12 in patients over 65 years old. Three-quarters of those injured were male. Kicking was the most common mechanism of injury (n=21), but charge/head-butt injuries and trampling injuries were associated with more serious injury scores. 72% of patients were admitted under Orthopaedics as their primary care team, 25% under General Surgeons, with one patient admitted medically. Mean ISS score was 6.9 (range 1-50). 41 operative interventions were performed on 30 patients during their admission. 6.3% of patients required admission to Intensive Care with a mean length of stay of 12.3 days (range 2-21 days). There was no mortality. Cow-related trauma is a common among farming communities and is a potentially serious mechanism of injury that appears to be under-reported in a hospital context. Bovine-related head-butt and trampling injuries should be considered akin to high-velocity trauma. (c) 2009 Elsevier Ltd. All rights reserved.

  14. Community structure and quality after 10 years in two central Ohio mitigation bank wetlands.

    Science.gov (United States)

    Spieles, Douglas J; Coneybeer, Meagan; Horn, Jonathan

    2006-11-01

    We evaluate two 10-year-old mitigation bank wetlands in central Ohio, one created and one with restored and enhanced components, by analysis of vegetation characteristics and by comparison of the year-10 vegetation and macroinvertebrate communities with reference wetlands. To assess different measures of wetland development, we compare the prevalence of native hydrophytes with an index of floristic quality and we evaluate the predictability of these parameters in year 10, given 5 years of data. Results show that the mitigation wetlands in this study meet vegetation performance criteria of native hydrophyte establishment by year 5 and maintain these characteristics through year 10. Species richness and floristic quality, as well as vegetative similarity with reference wetlands, differ among mitigation wetlands in year 1 and also in their rate of change during the first 10 years. The prevalence of native hydrophytes is reasonably predictable by year 10, but 5 years of monitoring is not sufficient to predict future trends of floristic quality in either the created or restored wetland. By year 10, macroinvertebrate taxa richness does not statistically differ among these wetlands, but mitigation wetlands differ from reference sites by tolerance index and by trophic guild dominance. The created wetland herbivore biomass is significantly smaller than its reference, whereas detritivore biomass is significantly greater in the created wetland and smaller in the restored wetland as compared with respective reference wetlands. These analyses illustrate differences in measures of wetland performance and contrast the monitoring duration necessary for legal compliance with the duration required for development of more complex indicators of ecosystem integrity.

  15. Patient-reported outcomes as predictors of 10-year survival in women after acute myocardial infarction

    Directory of Open Access Journals (Sweden)

    Segadal Leidulf

    2010-11-01

    Full Text Available Abstract Background Patient-reported outcomes are increasingly seen as complementary to biomedical measures. However, their prognostic importance has yet to be established, particularly in female long-term myocardial infarction (MI survivors. We aimed to determine whether 10-year survival in older women after MI relates to patient-reported outcomes, and to compare their survival with that of the general female population. Methods We included all women aged 60-80 years suffering MI during 1992-1997, and treated at one university hospital in Norway. In 1998, 145 (60% of those alive completed a questionnaire package including socio-demographics, the Sense of Coherence Scale (SOC-29, the World Health Organization Quality of Life Instrument Abbreviated (WHOQOL-BREF and an item on positive effects of illness. Clinical information was based on self-reports and hospital medical records data. We obtained complete data on vital status. Results The all-cause mortality rate during the 1998-2008 follow-up of all patients was 41%. In adjusted analysis, the conventional predictors s-creatinine (HR 1.26 per 10% increase and left ventricular ejection fraction below 30% (HR 27.38, as well as patient-reported outcomes like living alone (HR 6.24, dissatisfaction with self-rated health (HR 6.26, impaired psychological quality of life (HR 0.60 per 10 points difference, and experience of positive effects of illness (HR 6.30, predicted all-cause death. Major adverse cardiac and cerebral events were also significantly associated with both conventional predictors and patient-reported outcomes. Sense of coherence did not predict adverse events. Finally, 10-year survival was not significantly different from that of the general female population. Conclusion Patient-reported outcomes have long-term prognostic importance, and should be taken into account when planning aftercare of low-risk older female MI patients.

  16. Cow-related trauma: a 10-year review of injuries admitted to a single institution.

    LENUS (Irish Health Repository)

    Murphy, Colin G

    2012-02-01

    INTRODUCTION: Bovine-related injuries to farmers are common in rural communities. Many injuries are significant requiring hospital admission and surgery. We reviewed all cattle-related injuries admitted to a regional trauma centre over 10 years and detail the nature of the injuries. METHOD: A retrospective review was undertaken, using hospital inpatient coding system (HIPE) to identify patients admitted following cow-related trauma for the last 10 years. From retrieved charts mechanism of injury was identified, demographics recorded and Injury Severity Score (ISS) and Trauma Injury Severity Score (TRISS) calculated based on the injuries sustained. RESULTS: 47 patients were identified, with a median age of 53 years. 4 injuries occurred in children, and 12 in patients over 65 years old. Three-quarters of those injured were male. Kicking was the most common mechanism of injury (n=21), but charge\\/head-butt injuries and trampling injuries were associated with more serious injury scores. 72% of patients were admitted under Orthopaedics as their primary care team, 25% under General Surgeons, with one patient admitted medically. Mean ISS score was 6.9 (range 1-50). 41 operative interventions were performed on 30 patients during their admission. 6.3% of patients required admission to Intensive Care with a mean length of stay of 12.3 days (range 2-21 days). There was no mortality. CONCLUSION: Cow-related trauma is a common among farming communities and is a potentially serious mechanism of injury that appears to be under-reported in a hospital context. Bovine-related head-butt and trampling injuries should be considered akin to high-velocity trauma.

  17. Over 10 years follow-up of Coats' disease in adulthood

    Directory of Open Access Journals (Sweden)

    Otani T

    2011-12-01

    Full Text Available Tatsuro Otani1, Kanako Yasuda1, Naoko Aizawa2, Fumiaki Sakai3, Toru Nakazawa2, Masahiko Shimura11Department of Ophthalmology, NTT East Japan Tohoku Hospital, 2Department of Ophthalmology, Tohoku University School of Medicine, 3Heisei Ophthalmic Associates P.O., Sendai, Miyagi, JapanAbstract: Coats' disease diagnosed in adulthood is rare; therefore, the treatment options and longer clinical course are not well established. We report on two cases of adult onset Coats' disease, which have been observed for more than 10 years after conventional treatment. In the first case, a 76-year-old man with 9 years of diabetic retinopathy noticed a visual field defect in his left eye. Yellowish subretinal exudation with serous retinal detachment in his superior peripheral retina, and telangiectatic vessels with fluorescein leakage, numerous microaneurysms, and areas of capillary nonperfusion observed in a fluorescein angiography indicated adult Coats' disease, and retinal photocoagulation was applied. Within 1 year, subretinal exudation was regressed and visual acuity was improved from 20/50 to 20/20, and was maintained for the next 11 years. In the second case, a 71-year-old man presented with decreased vision in his right eye. The fundus of his right eye showed multiple telangiectasic vessels and subretinal exudates extended to the fovea, which is diagnosed as adult Coats’ disease. Despite retinal photocoagulation, an increase of exudation and an enlargement of retinal detachment was observed within 1 month, and subsequently, additional treatment of cryotherapy was performed. Two months after these therapies, the exudation was regressed without retinal detachment, and visual acuity was improved to 20/200 which was maintained for the next 10 years. Even with adult Coats’ disease, conventional therapies of retinal photocoagulation and cryotherapy are effective and are the initial choice for improving or maintaining visual function.Keywords: adult onset

  18. Energy-water analysis of the 10-year WECC transmission planning study cases.

    Energy Technology Data Exchange (ETDEWEB)

    Tidwell, Vincent Carroll; Passell, Howard David; Castillo, Cesar; Moreland, Barbara

    2011-11-01

    modules for calculating water withdrawal and consumption for current and planned electric power generation; projected water demand from competing use sectors; and, surface and groundwater availability. WECC's long range planning is organized according to two target planning horizons, a 10-year and a 20-year. This study supports WECC in the 10-year planning endeavor. In this case the water implications associated with four of WECC's alternative future study cases (described below) are calculated and reported. In future phases of planning we will work with WECC to craft study cases that aim to reduce the thermoelectric footprint of the interconnection and/or limit production in the most water stressed regions of the West.

  19. Accuracy and safety of free-hand pedicle screw fixation in age less than 10 years

    Directory of Open Access Journals (Sweden)

    Hyoung Yeon Seo

    2013-01-01

    Full Text Available Background: Pedicle screws are being used commonly in the treatment of various spinal disorders. However, use of pedicle screws in the pediatric population is not routinely recommended because of the risk of complications. The present study was to evaluate the safety of pedicle screws placed in children aged less than 10 years with spinal deformities and to determine the accuracy and complication (early and late of pedicle screw placement using the postoperative computed tomography (CT scans. Materials and Methods: Thirty one patients (11 males and 20 females who underwent 261 pedicle screw fixations (177 in thoracic vertebrae and 84 in lumbar vertebrae for a variety of pediatric spinal deformities at a single institution were included in the study. The average age of patients was 7 years and 10 months. These patients underwent postoperative CT scan which was assessed by two independent observers (spine surgeons not involved in the treatment. Results: Breach rate was 5.4% (14/261 screws for all pedicles. Of the 177 screws placed in the thoracic spine, 13 (7.3% had breached the pedicle, that is 92.7% of the screws were accurately placed within pedicles. Seven screws (4% had breached the medial pedicle wall, 4 screws (2.3% had breached the lateral pedicle wall and 2 screws (1.1% had breached the superior or inferior pedicle wall respectively. Of the 84 screws placed in the lumbar spine, 83 (98.8% screws were accurately placed within the pedicle. Only 1 screw (1.2% was found to be laterally displaced. In addition, the breach rate was found to be 4.2% (11/261 screws with respect to the vertebral bodies. No neurological, vascular or visceral complications were encountered. Conclusions: The accuracy of pedicle screw placement in pedicles and vertebral bodies were 94.6% and 95.8% respectively and there was no complication related to screw placement noted until the last followup. These results suggest that free-hand pedicle screw fixation can be safely

  20. Body mass index and skinfolds as indicators of obesity in schoolchildren aged 8 to 10 years

    Directory of Open Access Journals (Sweden)

    João Paulo Buraneli Mantoan

    2008-06-01

    Full Text Available The aim of this study was to compare the concordance of two obesity indicators, BMI and % body fat in boys and girls. Therefore, 100 girls and 100 boys, with ages ranging from 8 to 10 years, were submitted to anthropometric measurements for subsequent calculation of Body Mass Index (BMI and % body fat, both as obesity indicators. The variables were analyzed with relation to the reference criteria proposed by Williams et al and Cole et al. The results were then analyzed with the kappa index, elucidating that 79% of the boys and 85% of the girls were classified simultaneously by both procedures. The kappa index indicated a moderate agreement between the two obesity indicators for obese and non-obese classification. However, our data demonstrated that 21% of the boys and 15% of the girls showed normal weight according to BMI, but were classified as obese according to the % body fat. The results show that BMI, when compared with skinfolds, had moderate agreement in children from 8 to 10 years old for detecting obesity. ResumoO objetivo deste estudo foi comparar a concordância entre dois indicadores de obesidade, IMC e percentual de gordura, em escolares de ambos os sexos. Para tanto, 100 meninas e 100 meninos de 8 a 10 anos, alunos do ensino fundamental do município de Londrina, foram submetidos a medidas antropométricas para subseqüente cálculo do Índice de Massa Corporal (IMC e percentual de gordura como indicadores de obesidade. As variáveis foram analisadas em relação aos critérios de referência apresentados por Williams et al e Cole et al. Os resultados foram analisados pelo índice Kappa, evidenciando que 79% dos meninos e 85% das meninas foram classificados simultaneamente pelos dois procedimentos. Uma concordância moderada entre os dois indicadores de obesidade na classificação para meninos e meninas foi evidenciada (kappa=0,43 e 0,50, respectivamente. Entretanto, os dados encontrados demonstraram que 21% dos meninos e 15% das

  1. Human figure drawing test: validity in assessing intelligence in children aged 3-10 years.

    Science.gov (United States)

    Plubrukarn, Ratanotai; Theeramanoparp, Somchit

    2003-08-01

    Human-figure-drawing abilities are related with cognitive development in children. As cognitive skills progress, drawing abilities also improve in details and sex differentiation. The Goodenough-Harris (G-H) drawing test was developed to score human figure drawing with separate norms for males and females. To evaluate whether the Goodenough-Harris human drawing test is valid to classify intelligence in children aged 3-10 years. Record files of 528 children aged between 3-10 years who had attended the Child and Adolescent Unit at Queen Sirikit National Institute of Child Health (Children's Hospital), Bangkok, Thailand from January 1999 to December 2001 were retrospectively reviewed. Inclusion criteria included: 1) performing the human figure drawing test and standard intelligence tests on the same day and 2) diagnoses were addressed. The ages of the children ranged from 3 10/12 years to 10 11/12 years with a mean age of 7 9/12 years, 49.5 per cent were males and 50.5 per cent were female. The study group was diagnosed as pervasive development disorder 17 per cent, attention deficit hyperactivity disorder 13 per cent, and mental retardation 11.3 per cent. Overall correlation of full scale intellectual quotient (FSIQ) from the standard intelligence test and standard scores on the Goodenough-Harris system was 0.813 (p test in classified correct intellectual level was 60.8 per cent but in children with an intellectual quotient (IQ) less than 70, the correct classification was 69.2 per cent. After stratification by age, it was found that the human figure drawing test had validity in predicting IQ below 70 in 88.7 per cent and 68.8 per cent of children aged 6 years respectively. The human figure drawing test can be used as an additional measure of assessing intelligence in young children but it should not be substituted for standard tests. The test is not complicated, therefore, trained personnel can use it in combination with other screening tests for cognitive

  2. Effect of serum lipid level change on 10-year coronary heart risk distribution estimated by means of seven different coronary risk scores during one-year treatment.

    Science.gov (United States)

    Kojić, Nevena Eremić; Derić, Mirjana; Dejanović, Jadranka

    2014-01-01

    This study was done in order to evaluate the effect of serum levels of total cholesterol, triglycerides, low-density lipoprotein-cholesterol and high-density lipoprotein-cholesterol on 10-year coronary heart disease risk distribution change. This study included 110 subjects of both genders (71 female and 39 male), aged 29 to 73, treated at the Outpatient Department of Atherosclerosis Prevention, Centre for Laboratory Medicine, Clinical Centre Vojvodina. The 10-year coronary heart disease risk was estimated on first examination and after one-year treatment by means of Framingham, PROCAM and SCORE coronary risk scores and their modifications (Framingham Adult Treatment Panel III, Framingham Weibul, PROCAM NS and PROCAM Cox Hazards). Age, gender, systolic and diastolic blood pressure, smoking, positive family history and left ventricular hypertrophy are risk factors involved in the estimation of coronary heart disease besides lipid parameters. There were no significant differences in nutritional status, smoking habits, systolic and diastolic pressure, and no development of diabetes mellitus or cardiovascular incidents during one-year follow. However, a significant reduction in cholesterol level (p risk (Framingham- p Framingham ATP III- p Framingham Weibul- p SCORE- p risk category (Framingham- p Framingham ATP III- p Framingham Weibul- p SCORE- p risk at the beginning of the study. Our results show that the correction of lipid level after one-year treatment leads to a significant redistribution of 10-year coronary heart disease risk estimated by means of seven different coronary risk scores. This should stimulate patients and doctors to persist in prevention measures.

  3. Serum Lipid Levels and Dyslipidaemia Prevalence among 2–10 Year-Old Northern Mexican Children

    Science.gov (United States)

    Bibiloni, Maria del Mar; Salas, Rogelio; Novelo, Hilda I.; Villarreal, Jesús Z.; Sureda, Antoni; Tur, Josep A.

    2015-01-01

    Background and Aims The increase in overweight and obese children may be linked to increased rates of dyslipidaemia. The aim was to assess the prevalence of dyslipidaemia and associated risk factors among the Northern Mexican child population. Methods and Results Four hundred and fifty-one subjects aged between 2 and 10 (47.5% girls) took part in the Nuevo León State Survey of Nutrition and Health 2011–2012. According to the 2011 Expert Panel on Integrated Guidelines for Cardiovascular Health and Risk Reduction in Children and Adolescents, serum lipid levels (mg/dL) were categorized into three subgroups (acceptable, borderline-high/low or high/low) as follows: TChol: acceptable 45, borderline-low 40–45, low Obesity was associated with the occurrence of at least one abnormal lipid level. These findings emphasize the need to pay further attention to the prevention of cardiovascular disease and obesity from an early age. PMID:25793380

  4. Strategy for elimination of iodine deficiency in Belarus: evaluation of 10 years experience

    Directory of Open Access Journals (Sweden)

    V I Kachan

    2010-09-01

    Full Text Available Article presents results of implementation of successful program of elimination of iodine deficiency in Belarus. Government decree (2001 requires mandatory use of iodized salt in food industry and public catering. While retail trade of non-iodized salt is not prohibited, all foods shops must have iodized salt on sale. All these measures resulted in increase of iodized salt consumption: 94% of house-holds in Belarus were using iodized salt. Iodine nutrition of population also sig-nificantly improved: median urinary iodine levels in general population (school-children reached 169 mcg/l and in pregnant women – 224 mcg/l. Endemic goiter morbidity decreased significantly in children, adolescents and adults as well as frequency of transitory thyroid dysfunctions in newborns. Belarus experience in prevention of iodine deficiency can be used by other industrialized countries of Europe and rest of the world.

  5. The Effect of Executive Function on Science Achievement Among Normally Developing 10-Year Olds

    Science.gov (United States)

    Lederman, Sheri G.

    Executive function (EF) is an umbrella term used to identify a set of discrete but interrelated cognitive abilities that enable individuals to engage in goal-directed, future-oriented action in response to a novel context. Developmental studies indicate that EF is predictive of reading and math achievement in middle childhood. The purpose of this study was to identify the association between EF and science achievement among normally developing 10 year olds. A sample of fifth grade students from a Northeastern suburban community participated in tests of EF, science, and intelligence. Consistent with adult models of EF, principal components analysis identified a three-factor model of EF organization in middle childhood, including cognitive flexibility, working memory, and inhibition. Multiple regression analyses revealed that executive function processes of cognitive flexibility, working memory, and inhibition were all predictive of science performance. Post hoc analyses revealed that high-performing science students differed significantly from low-performing students in both cognitive flexibility and working memory. These findings suggest that complex academic demands specific to science achievement rely on the emergence and maturation of EF components.

  6. Sphenoid sinus fungall ball: a retrospective study over a 10- year period.

    Science.gov (United States)

    Eloy, Ph; Grenier, J; Pirlet, A; Poirrier, A L; Stephens, J S; Rombaux, Ph

    2013-06-01

    A fungal ball consists of a dense conglomerate of fungal hyphae growing at the surface of the sinus mucosa without tissue infiltration. The maxillary sinus is by far the most commonly involved paranasal sinus cavity followed by the sphenoid sinus. The present study is a retrospective study of 25 consecutive cases treated during the last 10 years in the two hospitals be- longing to the Catholic University of Louvain (CHU Mont-Godinne and UCL Saint Luc). We report the symptomatology, the imaging and discuss the different surgical managements. We conclude that the clinician must have a high index of suspicion when dealing with a unilateral rhinosinusitis persisting despite a maximal and well conducted medical treatment. This is particularly so in elderly women when associated with facial pain and post nasal drip, particularly when the computed tomography shows an unilateral opacity of the sphenoid sinus with or without a sclerosis or an erosion of the bony walls, a polyp in the sphenoethmoidal recess or a hyperdensity mimicking a foreign body. An endonasal endoscopic sphenoidotomy is the treatment of choice in most cases, allowing good ventilation of the sinus and radical removal of all the fungal concretion. A biopsy of the sinus mucosa adjacent to fungal elements is of upmost important to confirm the non- invasiveness of the fungi within the tissue. Antifungal medication is not required in uncomplicated forms. All host factors producing some degree of immunosuppression must be corrected when present and must alert the clinician to rule out any forms of invasive disease.

  7. Neural Substrates of the Development of Cognitive Control in Children Ages 5–10 Years

    Science.gov (United States)

    Sheridan, Margaret; Kharitonova, Maria; Martin, Rebecca E.; Chatterjee, Aparna; Gabrieli, John D. E.

    2014-01-01

    Cognitive conflict detection and resolution develops with age across childhood and likely supports age-related increases in other aspects of cognitive and emotional development. Little is known about the neural correlates of conflict detection and resolution in early childhood. In the current study, we investigated age-related change in neural recruitment during a blocked spatial-incompatibility task (Simon task) in children ages 5–10 years using fMRI. Cortical thickness was measured using structural MRI. Across all children, there was greater activation in right prefrontal and bilateral parietal cortices for incompatible than compatible conditions. In older children, compared with younger children, there was decreased activation and decreased gray matter thickness in the medial pFC. Thickness and activation changes across age were associated within participants, such that thinner cortex was associated with less activation in the rostral ACC. These findings suggest that developmental change in medial pFC activation supports performance on cognitive control tasks in early childhood. PMID:24650280

  8. Upper Gastrointestinal Bleeding in Chinese Children: A Multicenter 10-Year Retrospective Study.

    Science.gov (United States)

    Yu, Yi; Wang, Baoxiang; Yuan, Lan; Yang, Hui; Wang, Xinqiong; Xiao, Yuan; Mei, Hong; Xu, Chundi

    2016-08-01

    Objective This study aims to analyze the clinical and endoscopic presentations of upper gastrointestinal bleeding (UGIB) in the Chinese children. Methods A 10-year retrospective study was made on children with UGIB and undertaken esophagogastroduodenoscopy (EGD) from 4 tertiary referral centers in China. Results Of the 1218 children studied, the bleeding source was found in 76.4%. Erosive gastritis was the most common endoscopic finding (33.5%), followed by duodenal ulcer (23.2%). The proportion of erosive gastritis decreased with age (correlation coefficient = -0.787), and duodenal ulcer increased with age (correlation coefficient = 0.958). The bleeding source was more likely to be determined in children having EGDs within 48 hours (80.6% vs 67.9%). Conclusions In Chinese children with UGIB, erosive gastritis and duodenal ulcer were the leading causes, and their proportions varied with age. EGDs performed within 48 hours may improve the possibility of finding the source of bleeding. © The Author(s) 2015.

  9. A 10-year longitudinal fMRI study of narrative comprehension in children and adolescents.

    Science.gov (United States)

    Szaflarski, Jerzy P; Altaye, Mekibib; Rajagopal, Akila; Eaton, Kenneth; Meng, Xiangxiang; Plante, Elena; Holland, Scott K

    2012-11-15

    Comprehension of spoken narratives requires coordination of multiple language skills. As such, for normal children narrative skills develop well into the school years and, during this period, are particularly vulnerable in the face of brain injury or developmental disorder. For these reasons, we sought to determine the developmental trajectory of narrative processing using longitudinal fMRI scanning. 30 healthy children between the ages of 5 and 18 enrolled at ages 5, 6, or 7, were examined annually for up to 10 years. At each fMRI session, children were presented with a set of five, 30s-long, stories containing 9, 10, or 11 sentences designed to be understood by a 5 year old child. fMRI data analysis was conducted based on a hierarchical linear model (HLM) that was modified to investigate developmental changes while accounting for missing data and controlling for factors such as age, linguistic performance and IQ. Performance testing conducted after each scan indicated well above the chance (pdevelopment of this area throughout childhood and teenage years with no apparent plateau, indicates that full maturation of narrative processing skills has not yet occurred and that it may be delayed to early adulthood.

  10. Improving the TNM classification: findings from a 10-year continuous literature review.

    Science.gov (United States)

    Webber, Colleen; Gospodarowicz, Mary; Sobin, Leslie H; Wittekind, Christian; Greene, Frederick L; Mason, Malcolm D; Compton, Carolyn; Brierley, James; Groome, Patti A

    2014-07-15

    The Union for International Cancer Control's (UICC) TNM classification is a globally accepted system to describe the anatomic extent of malignant tumors. Since its development seventy years ago, the TNM classification has undergone significant revisions to reflect the current understanding of extent of disease and its role in prognosis. To ensure that revisions are evidence-based, the UICC implemented a process for continuous improvement of the TNM classification that included a formalized system for submitting proposals for revisions directly to the UICC and an annual review of the scientific literature on staging that assessed, criticized or made suggestions for changes. The process involves review of the proposals and literature by a group of international, multidisciplinary Expert Panels. The process has been in place for 10 years and informed the development of the 7th edition of the TNM classification published in 2009. The purpose of this article is to provide a description of the annual literature review process, including the search strategy, article selection process and the roles and requirements of the Expert Panels in the review of the literature. Since 2002, 147 Expert Panel members in 11 cancer sites have reviewed over 770 articles. The results of the annual literature reviews, Expert Panel feedback and documentation and dissemination of results are described.

  11. Does gymnastics practice improve vertical jump reliability from the age of 8 to 10 years?

    Science.gov (United States)

    Marina, Michel; Torrado, Priscila

    2013-01-01

    The objective of this study was to confirm whether gymnastics practice from a young age can induce greater vertical jump reliability. Fifty young female gymnasts (8.84 ± 0.62 years) and 42 females in the control group (8.58 ± 0.92 years) performed the following jump tests on a contact mat: squat jump, countermovement jump, countermovement jump with arm swing and drop jump from heights of 40 and 60 cm. The two testing sessions had three trials each and were separated by one week. A 2 (groups) × 2 (sessions) × 3 (trials) repeated measures analysis of variance (ANOVA) and a test-retest correlation analysis were used to study the reliability. There was no systematic source of error in either group for non-plyometric jumps such as squat jump, countermovement jump, and countermovement jump with arm swing. A significant group per trial interaction revealed a learning effect in gymnasts' drop jumps from 40 cm height. Additionally, the test-retest correlation analysis and the higher minimum detectable error suggest that the quick drop jump technique was not fully consolidated in either group. At an introductory level of gymnastics and between the ages of 8-10 years, the condition of being a gymnast did not lead to conclusively higher reliability, aside from better overall vertical jump performance.

  12. Dynamics of comprehensive physical fitness in artistic gymnasts aged 7-10 years

    Directory of Open Access Journals (Sweden)

    Boraczyńska Sandra

    2014-12-01

    Full Text Available Purpose: The aim of the study was to evaluate the somatic development and comprehensive physical fitness of artistic gymnasts aged 7-10 years. Materials and methods: Gymnasts (n = 307, split up into four age groups performed eight Eurofit tests. The results were evaluated in points according to the development standards prepared in scale T for the Polish girls population. Results : The gymnasts obtained the highest growth rate in balance test - FLB (13 points, arm and shoulder muscular endurance test - BAH (7 points and speed of the upper limb movement test - PLT (4 points out of eight physical fitness tests. Conclusions. High and very high level of performance in the six Eurofit tests and increased total number of points in the subsequent age groups of artistic gymnasts proved high effectiveness of training in shaping the key components of a comprehensive physical fitness in artistic gymnastics - balance, strength, endurance, speed and flexibility. Relatively little progress in isometric hand strength (HGR and standing broad jump (SBJ suggests a significant influence of genetic factors on the level of these abilities. The results provide an objective information useful in optimizing control system of training effects in comprehensive physical fitness and optimization of artistic gymnasts training at the comprehensive stage of sports training.

  13. Antimetropia in a 10-year-old boy with unilateral tilted disc syndrome

    Directory of Open Access Journals (Sweden)

    Makino S

    2014-05-01

    Full Text Available Shinji MakinoDepartment of Ophthalmology, Jichi Medical University, Shimotsuke, Tochigi, JapanAbstract: Antimetropia is a condition in which one eye is myopic, while the fellow eye is hyperopic. This report describes a case of antimetropia associated with unilateral tilted disc syndrome. A 10-year-old boy presented with the complaint of diminished vision for distant objects in his right eye for several months. His uncorrected distance visual acuity was 0.15 in the right eye and 1.0 in the left eye. Best corrected visual acuity was 1.0, with -6.00 D/-2.00 D 170° in the right eye and +1.50 D in the left eye. The cover test revealed right esotropia and hypertropia. Bifoveal fixation was achieved using a 14 prism diopter (PD base at 220° in the right eye. Fundus examination revealed a tilted disc with inferior staphyloma in the right eye, but no abnormal findings were observed in the left eye. In addition, the patient occasionally experienced diplopia under casual viewing conditions. A cycloplegic refraction revealed -6.00 D/-2.00 D 170° in the right eye and +1.50 D/-2.00 D 5° in the left eye. Thus, prism glasses were prescribed. While wearing the prism glasses, the patient has shown no diplopia and maintains good binocular function.Keywords: amblyopia, strabismus, anisometropia, staphyloma

  14. FNAC FINDINGS IN CHILDREN AGED 1-10 YEARS WITH CERVICAL LYMPHADENOPATHY

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    Bhatia

    2014-07-01

    Full Text Available INTRODUCTION: Cervical lymphadenopathy is a common presenting complaint in the pediatric outdoor. Often it is a cause of concern for the parents and very often poses a diagnostic dilemma for the treating pediatrician. The study was planned with the aim of trying to find out an etiological cause for cervical lymhadenopathy. MATERIAL AND METHODS: 109 children who were referred to Arravali path labs for FNAC of cervical lymph nodes formed the basis of study. Detailed history was recorded in predesigned proforma, along with a general physical exam for each patient. FNAC was done by a pathologist. RESULTS: The predominant group of patients was in the 6-10 year age group with 60 cases. The commonest clinical symptom was swelling in the neck region (109 cases, loss of weight and appetite (54 cases, fever (45 cases. Reactive hyperplasia and tuberculosis lymphadenitis were the commonest cyto-pathological findings noted on FNAC. CONCLUSION: Infection remains the predominant cause of cervical lymphadenopathy among children in our country.

  15. Cryobanking of Korean allium germplasm collections: results from a 10 year experience.

    Science.gov (United States)

    Kim, H H; Popova, E; Shin, D J; Yi, J Y; Kim, C H; Lee, J S; Yoon, M K; Engelmann, F

    2012-01-01

    This paper reviews a 10-year experience in establishing a cryopreserved Allium germplasm collection at the genebank of the National Agrobiodiversity Center, Republic of Korea. A systematic approach to Allium cryopreservation included: 1. revealing the most critical factors that affected regeneration after cryostorage; 2. understanding the mechanisms of cryoprotection by analyzing the thermal behavior of explants and cryoprotectant solutions using DSC and influx/efflux of cryoprotectants using HPLC; 3. assessing genetic stability of regenerants; and 4. revealing the efficiency of cryotherapy. Bulbil primordia, i.e. asexual bulbs formed on unripe inflorescences, proved to be the most suitable material for conservation of bolting varieties due to high post-cryopreservation regrowth and lower microbial infection level, followed by apical shoot apices from single bulbs and cloves. A total of 1,158 accessions of garlic as well as some Allium species have been cryopreserved during 2005-2010 using the droplet-vitrification technique with a mean regeneration percentage of 65.9 percent after cryostorage. These results open the door for large-scale implementation of cryostorage and for simplifying international exchange for clonal Allium germplasm.

  16. Soil physical quality changes under different management systems after 10 years in Argentinian Humid Pampa

    Science.gov (United States)

    Costa, J. L.; Aparicio, V. C.; Cerda, A.

    2014-08-01

    The Argentinian Humid Pampa extends over about 60 million ha, 90% of which are agricultural lands. The southeast of the Buenos Aires Province is part of the Humid Pampa (1 206 162 ha). The main crops are wheat, sunflower, corn and soybean. The management systems used in the area are: moldboard plow (MP), chisel plow (CP) and no-till (NT). Excessive soil cultivation under MP causes decreases in the soil organic carbon content (SOC). Adopting NT may reduce the effects of intensive agriculture, through the maintenance and accumulation of SOC. However, the soil compaction under NT causes degradation of the soil structure, reduces the soil water availability and reduces the soil hydraulic conductivity. We evaluated the evolution of the soil physical parameters in three management systems. After 10 years of experiments in four farmers' fields, we found that: soil bulk density was significantly higher under NT. The change in mean weight diameter (CMWD) of aggregates increased as the management system became more intensive. We did not find significant differences in time and management systems in hydraulic conductivity at tension (h)0 cm and h=20 cm. The reduction in total porosity under NT is mainly a product of a reduction in the percentage of mesopores in the soil. Time had no statistically significant effect on the SOC content. The management system did not affect the yields of crop. In this work, the results indicate a modification of some soil physical parameters (porosity, near-saturated hydraulic conductivity, soil structure) due to uninterrupted agricultural production.

  17. Rib cartilage graft for posttraumatic or degenerative arthritis at wrist level: 10-year results.

    Science.gov (United States)

    Obert, Laurent; Lepage, Daniel; Ferrier, Maxime; Tropet, Yves

    2013-08-01

    Background Posttraumatic arthritides of the radiocarpal joint, secondary to scaphoid nonunion advanced collapse (SNAC), scapholunate advanced collapse (SLAC), or Kienböck disease or in cases of intraarticularmalunion of the distal radius, are classically solved by some type of arthrodesis procedure. Osteochondral grafting provides a possible motion-sparing option that can diminish pain in the active patient. Description of Technique A chondrocostal graft harvested from the ninth rib was inserted and fixed with a plate in place of the articular defect in cases of a malunited intra-articular distal radius fracture (7 cases) or to replace the proximal pole of the scaphoid in cases of SNAC or SLAC (18 cases). In Kienböck disease, the graft was inserted as a free cartilage spacer (4 cases). Results Harvesting the graft from the ninth rib had minimal morbidity without pleural injury in the reported series. Graft union was achieved in all cases of fixation. No graft resorption or necrosis were observed on X-ray and magnetic resonance imaging (MRI) evaluation at the longest follow-up of 10 years. Histological analysis performed at the time of plate removal showed the vitality of the graft. Two thirds of the patients had excellent or good results using the Green and O'Brien score. Conclusions Reconstruction of a partially destroyed articular surface using a costal graft is reliable and provides an alternative option for resurfacing the articular surface with viable cartilage.

  18. Hippocampus, amygdala and global brain changes 10 years after childhood traumatic brain injury.

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    Beauchamp, M H; Ditchfield, M; Maller, J J; Catroppa, C; Godfrey, C; Rosenfeld, J V; Kean, M J; Anderson, V A

    2011-04-01

    Traumatic brain injury (TBI) in children results in damage to the developing brain, particularly in severely injured individuals. Little is known, however, of the long-term structural aspects of the brain following childhood TBI. This study investigated the integrity of the brain 10 years post-TBI using magnetic resonance imaging volumetrics in a sample of 49 participants with mild, moderate and severe TBI, evaluated against a normative sample of 20 individuals from a pediatric database with comparable age and gender distribution. Structural integrity was investigated in gray and white matter, and by manually segmenting two regions of interest (hippocampus, amygdala), potentially vulnerable to the effects of childhood TBI. The results indicate that more severe injuries caused a reduction in gray and white brain matter, while all TBI severity levels resulted in increased volumes of cerebrospinal fluid and smaller hippocampal volumes. In addition, enlarged amygdala volumes were detected in severely injured patients compared to their mild and moderate counterparts, suggesting that childhood TBI may disrupt the development of certain brain regions through diffuse pathological changes. The findings highlight the lasting impact of childhood TBI on the brain and the importance of monitoring brain structure in the long-term after early injury. Copyright © 2010 ISDN. Published by Elsevier Ltd. All rights reserved.

  19. The Ecology of Sustainable Implementation: Reflection on a 10-Year Case History Illustration.

    Science.gov (United States)

    Rimehaug, Tormod

    2014-01-01

    The primary aim of this paper is to illustrate the strategic and ecological nature of implementation. The ultimate aim of implementation is not dissemination but sustainability beyond the implementation effort. A case study is utilized to illustrate these broad and long-term perspectives of sustainable implementation based on qualitative analyses of a 10-year implementation effort. The purveyors aimed to develop selective community prevention services for children in families burdened by parental psychiatric or addictive problems. Services were gradually disseminated to 23 sites serving 40 municipalities by 2013. Up to 2013, only one site terminated services after initial implementation. Although many sites suspended services for shorter periods, services are still offered at 22 sites. This case analysis is based on project reports, user evaluations, practitioner interviews, and service statistics. The paper focuses on the analyses and strategies utilized to cope with quality decay and setbacks as well as progress and success in disseminating and sustaining the services and their quality. Low-cost multilevel strategies to implement services at the community level were organized by a prevention unit in child psychiatry, supervised by a university department (purveyors). The purveyors were also involved in national and international collaboration and development. Multilevel strategies included manualized intervention, in-practice training methods, organizational responsibility, media strategies, service evaluation, staff motivation maintenance, quality assurance, and proposals for new law regulations. These case history aspects will be discussed in relation to the implementation literature, focusing on possible applicability across settings.

  20. Social functioning and survival: A 10-year follow-up study.

    Science.gov (United States)

    Arve, Seija; Lavonius, Sirkku; Savikko, Niina; Lehtonen, Aapo; Isoaho, Hannu

    2009-01-01

    Although otherwise extensively researched, one aspect of social functioning in older people that has received less attention is its association with staying at home for as long as possible. This 10-year follow-up examines factors of social functioning that support older people's independent living in their own homes and that reduce the risk of mortality. The data were collected in 1991 by a postal questionnaire that was sent to all residents of Turku, Finland, born in 1920. A physical examination was also conducted. Ten years later, in 2001, the mortality rate of this population was determined. The data were examined statistically. Female gender reduced the risk of mortality. In addition, daily outdoor activities, and not needing help (from different sources) were associated with a reduced risk of mortality. No need for help and a more positive attitude towards life reduced the risk of mortality of women. There were found only non-significant trends for men. Having plans for the future also reduced the risk of mortality. The findings of this study offer useful clues for planning the services provided by home health care personnel. In planning these services it is important that home health care workers take into account the differences between women and men customers: men may need and want different things from the home health care service than women do.

  1. Early treatment of Class III malocclusion: 10-year clinical follow-up

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    Marcio Rodrigues de Almeida

    2011-08-01

    Full Text Available Angle Class III malocclusion has been a challenge for researchers concerning diagnosis, prognosis and treatment. It has a prevalence of 5% in the Brazilian population, and may have a genetic or environmental etiology. This malocclusion can be classified as dentoalveolar, skeletal or functional, which will determine the prognosis. Considering these topics, the aim of this study was to describe and discuss a clinical case with functional Class III malocclusion treated by a two-stage approach (interceptive and corrective, with a long-term follow-up. In this case, the patient was treated with a chincup and an Eschler arch, used simultaneously during 14 months, followed by corrective orthodontics. It should be noticed that, in this case, initial diagnosis at the centric relation allowed visualizing the anterior teeth in an edge-to-edge relationship, thereby favoring the prognosis. After completion of the treatment, the patient was followed for a 10-year period, and stability was observed. The clinical treatment results showed that it is possible to achieve favorable outcomes with early management in functional Class III malocclusion patients.

  2. Children of treated substance-abusing mothers: a 10-year prospective study.

    Science.gov (United States)

    Hser, Y-I; Evans, E; Li, L; Metchik-Gaddis, A; Messina, N

    2014-04-01

    This study examined children of substance-abusing mothers approximately 10 years after mothers' admission to drug abuse treatment, and identified maternal characteristics that may be risk factors for child behavior problems on the Child Behavior Checklist. Data were obtained from 396 mothers who were included in a sample consecutively admitted to 44 treatment programs in 13 California counties during 2000-2002. The Addiction Severity Index was administered at both intake and follow-up. Each mother reported on one child 6-17 years of age. All of the children had been exposed to drugs, either in utero or postnatally. At follow-up about 22% of the children demonstrated borderline or clinical range problem behaviors. Child behavior problems were related significantly to the mothers' ethnicity (lower among Hispanics relative to white), and problem severity in family/social relationship and mental health, marginally related to her prior medical/health problem, and not related to severity of alcohol, drug, legal and employment problems. Assisting mothers to address their family/social relationship and psychological problems may have an added value to prevent or reduce behavioral problems of their children.

  3. Mortality in perforated duodenal ulcer depends upon pre-operative risk: a retrospective 10-year study.

    LENUS (Irish Health Repository)

    Larkin, J O

    2012-01-31

    INTRODUCTION: Most patients presenting with acutely perforated duodenal ulcer undergo operation, but conservative treatment may be indicated when an ulcer has spontaneously sealed with minimal\\/localised peritoneal irritation or when the patient\\'s premorbid performance status is poor. We retrospectively reviewed our experience with operative and conservative management of perforated duodenal ulcers over a 10-year period and analysed outcome according to American Society of Anesthesiologists (ASA) score. METHODS: The records of all patients presenting with perforated duodenal ulcer to the Department of Surgery, Mayo General Hospital, between January 1998 and December 2007 were reviewed. Age, gender, co-morbidity, ASA-score, clinical presentation, mode of management, operative procedures, morbidity and mortality were considered. RESULTS: Of 76 patients included, 48 (44 operative, 4 conservative) were ASA I-III, with no mortality irrespective of treatment. Amongst 28 patients with ASA-score IV\\/V, mortality was 54.5% (6\\/11) following operative management and 52.9% (9\\/17) with conservative management. CONCLUSION: In patients with a perforated duodenal ulcer and ASA-score I-III, postoperative outcome is uniformly favourable. We recommend these patients have repair with peritoneal lavage performed, routinely followed postoperatively by empirical triple therapy. Given that mortality is equivalent between ASA IV\\/V patients whether managed operatively or conservatively, we suggest that both management options are equally justifiable.

  4. Common Causes of Postmenopausal Bleeding in Korean Women: 10-Year Outcomes from a Single Medical Center.

    Science.gov (United States)

    Kim, Min Kyoung; Jung, Yeon Soo; Chon, Seung Joo; Yun, Bo Hyon; Cho, Sihyun; Choi, Young Sik; Lee, Byung Seok; Seo, Seok Kyo

    2017-05-01

    The common causes of postmenopausal bleeding (PMB), according to the data from the western world, are atrophy, hormone replacement therapy (HRT), endometrial cancer, etc. We conducted a retrospective study to assess whether the causes of PMB in Korean postmenopausal women are similar to those already known. This retrospective study used 10-year medical records (March 2005 to December 2014) of 792 PMB women in the Yonsei University Health System. The data were divided into 2 categories by 5-year intervals to compare the differences between the 2 periods. The most common cause of PMB in Korean women was atrophy (51.1%). Polyps and HRT were the second, followed by anticoagulant medications, cervical cancer, and endometrial cancer. The proportion of patients with cervical cancer significantly decreased during the second half of the decade (8.7% vs. 5.2%; P = 0.048). Although no significant change was noted for HRT, its rank was higher during the latter 5-year period. Only the most common cause of PMB was the same as the conventional data. Interestingly, the proportion of patients with cervical cancer decreased during the latter half of the decade, reflecting the changes in the nation's cancer prevalence rate, while the use of HRT increased. © 2017 The Korean Academy of Medical Sciences.

  5. Surgical treatment of gingival overgrowth with 10 years of follow-up

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    Ballini Andrea

    2010-08-01

    Full Text Available Abstract Background In some pathological conditions, gingivitis caused by plaque accumulation can be more severe, with the result of an overgrowth. Nevertheless, the overgrowth involves the gingival margin with extension to the inter-dental papilla. The lesion may involve the inter-proximal spaces, and become so extensive that the teeth are displaced and their crowns covered. Severe overgrowth may lead to impairment in aesthetic and masticatory functions, requiring surgical excision of the excessive tissue. Aim of this study is to describe an operative protocol for the surgical treatment of localized gingival overgrowth analyzing the surgical technique, times and follow-up. Methods A total of 20 patients were enrolled and underwent initial, non surgical, periodontal treatment and training sessions on home oral hygiene training. The treatment plan involved radical exeresis of the mass followed by positioning of an autograft of connective tissue and keratinized gingiva. Results During 10 years of follow-up, all the grafts appeared well vascularized, aesthetically satisfactory, and without relapse. Conclusions Periodontal examinations, surgical procedures, and dental hygiene with follow-up are an essential part of the treatment protocol. However, additional effort is needed from the patient. Hopefully, the final treatment result makes it all worthwhile.

  6. Operations, Maintenance, and Replacement 10-Year Plan 1990-1999 : Environmental Strategy. Final Report.

    Energy Technology Data Exchange (ETDEWEB)

    United States. Bonneville Power Administration.

    1990-09-01

    In operating and maintaining its regional power transmission system, Bonneville Power Administration (BPA) must address environmental concerns. Pollution sources and pathways for pollution migration, including potential contamination from hazardous or toxic materials, are present. BPA must develop and follow precautionary measures, respond to emergencies, minimize wastes, redress past problems, alert and train employees to problems and safety needs, constantly evaluate this effort and update the program for improvements and changes in regulations and technology. Part of BPA's mission is to conduct its operation, maintenance, and replacement programs in an environmentally sound manner. BPA recognizes its responsibility to be good stewards of the environment. BPA will meet its environmental obligations as set forth in environmental laws and regulations. BPA intends to make consistent and measurable progress toward meeting these responsibilities. The target for the 10-Year Plan is to achieve environmental compliance and meet the following goals: (1) protect human health and the environment; (2) avoid or limit liability (3) set up an effective internal management structure to maintain compliance; and (4) achieve cost-effective compliance. 6 figs.

  7. Evaluation and outcomes of pediatric pleural effusions in over 10 years in Northwest, Iran

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    Mohammad Hassan Kargar maher

    2014-08-01

    Full Text Available Abstract Background: Pleural effusion is the accumulation of excess fluid in the pleural cavity. Most information available about pleural effusion is obtained from studies on adults and little evidence is available in children. Therefore, it is necessary to identify the existing status and explain the disease process, signs, treatment, and prognosis. Children with pleural effusion who were admitted to children’s university hospital during the last ten years were studied in this research. Methodology: In this descriptive research, children with pleural effusion who were admitted and undergone thoracocentesis in the children’s university hospital during the last ten years were studied. The data obtained from in vitro experiments and the information questionnaire was analyzed using SPSS-18 through descriptive statistics of frequency, percent, and mean. Findings: Ninety-four children with pleural effusion were admitted during 10 years. Pleural effusion was exudate in 56.38% and transudate in 43.61% of children. The most common symptoms were tachypnea, fever, and cough. Antibiotic administration was the most performed therapeutic action. Conclusion: The mode of addressing pleural effusion in this research was similar to other studies. Considering the results, better planning can be performed regarding preventing this disease or improving its prognosis.

  8. Newspaper Coverage of Autism Treatment in Canada: 10-Year Trends (2004–2013)

    Science.gov (United States)

    Lanovaz, Marc J; Dufour, Marie-Michèle; Shah, Shalaka

    2015-01-01

    Objective: To compare trends in coverage of empirically supported and alternative autism treatments in Canadian newspapers during a 10-year period and to examine whether the portrayal of empirically supported and alternative treatments differed. Method: We searched a sample of 10 daily local and national Canadian newspapers using the word autism combined with intervention or treatment in the Proquest Canadian Newsstand and Eureka.cc databases, which yielded a total of 857 articles published between 2004 and 2013. In our subsequent analyses, we only included articles whose main topic was autism and that referred to at least one treatment. We then categorized the 137 remaining articles by treatment and rated whether each treatment category was portrayed in a favourable, unfavourable, or neutral manner. Results: In total, 46% of the articles discussed at least 1 empirically supported treatment, 53% at least 1 alternative treatment, and 12% at least 1 uncategorized treatment. Newspaper articles provided favourable, unfavourable, and neutral portrayals of empirically supported treatments in 75%, 10%, and 16% of cases, respectively. In contrast, alternative treatments were portrayed favourably in 52%, unfavourably in 32%, and neutrally in 16% of cases. Our analyses indicated that empirically supported treatments were portrayed more favourably than alternative treatments (χ2 = 10.42, df = 2, P = 0.005). Conclusions: Despite some encouraging trends, our study has shown that researchers and clinicians must continue to clarify misconceptions about autism treatment. Families of people with autism spectrum disorders should be directed toward more reliable and accurate sources of information. PMID:26175392

  9. Primary Germ Cell Tumors of the Mediastinum: 10 Years of Experience in a Tertiary Teaching Hospital

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    Chih-Jen Yang

    2005-09-01

    Full Text Available Germ cell tumors occur mostly in the gonad. Extragonadal germ cell tumors are rare, and most occur in the retroperitoneum and mediastinum. Primary mediastinal germ cell tumors are often found in the anterior portion of the mediastinum and include teratomas and non-teratomatous tumors. Non-teratomatous tumors include seminomas and malignant non-seminomatous germ cell tumors (MNSGCTs. MNSGCTs include yolk sac tumors, choriocarcinomas, embryonal carcinomas, and mixed type germ cell tumors. Teratomas are the most common germ cell tumors of the mediastinum, and seminomas are the most common non-teratomatous germ cell tumors of the mediastinum. Cases of primary mediastinal MNSGCT reported in the literature are rare. In this report, we review all primary mediastinal germ cell tumors from a 10-year period at the Chung-Ho Memorial Hospital of Kaohsiung Medical University. A total of 14 cases were reviewed, including 11 patients with mature teratomas, two with yolk sac tumors, and one with seminoma. We discuss the differences in clinical presentation, histopathologic characteristics, treatment, and prognosis.

  10. Adverse effects of hydroxyurea in beta-thalassemia intermedia patients: 10 years' experience.

    Science.gov (United States)

    Karimi, Mehran; Cohan, Nader; Mousavizadeh, Kazem; Moosavizadeh, Kazem; Falahi, Mohammad Javad; Haghpanah, Sezaneh

    2010-04-01

    The aim of this study was to evaluate the tolerance and adverse effects of hydroxyurea (HU) in thalassemia intermedia (TI) patients who had been treated by HU for a period of 10 years. One hundred forty-three TI patients, including 78 male and 65 female, median age 21 years old (range: 5-37 years old), who were treated by HU were investigated as a case study, and 106 TI, including 63 male and 43 female, median age 22 years old (range: 5-39 years old), who were not treated by any HU as a control group. Mean dose of HU treatment was 10.74 mg/kg/day (range: 8-12 mg/kg/day) and adverse effects of HU were recorded in 44 (30.7%) patients. Dermatologic side effects were most commonly seen, followed by neurological and gastrointestinal adverse effects. There were not any reports of hematologic toxicity or any signs of bone marrow suppression during HU treatment. Statistical analysis showed a positive correlation between advancing age and the presence of adverse effects during HU treatment (P treatment and the presence of adverse effects (P > .05). It was also observed that splenectomized patients more frequently experienced adverse effects of HU (P minor and can be tolerated without needs of discontinuation of treatment.

  11. Reference limits and behaviour of serum transferrin receptor in children 6-10 years of age.

    Science.gov (United States)

    Danise, P; Maconi, M; Morelli, G; Di Palma, A; Rescigno, G; Esposito, C; Avino, D; Talento, B

    2008-08-01

    Serum transferrin receptor (sTfR) originates mostly from erythroblasts and lesser from reticulocytes. The usefulness of sTfR has been implicated in several clinical situations, mainly as a marker of accelerated erythropoiesis or iron deficiency. The assessment of sTfR may be useful in the period of rapid growth during infancy, childhood and adolescence. We evaluated sTfR and the other quantitative and qualitative parameters of the erythropoiesis (Hb, MCV, CHr, Ret-He) and of the iron storage (serum ferritin, sTfR/ferritin index) in a total of 916 children aged 6-10 years. Children were divided into three groups: (A) healthy children, (B) with storage iron deficiency (serum ferritin 3.3). We determined reference intervals by sex and by age in healthy children. sTfR showed a slight but statistically significant age related increase but did not show significant sex differences. We compared sTfR and the other parameters investigated in the three groups of children. sTfR is not a decisive parameter that can be utilized alone in discriminating the border-line situations between normal and pathologic ones but can help in completing the panel of tests in iron deficiency and in thalassaemia Beta trait carriers.

  12. Factors affecting diatom dynamics in the alpine lakes of Colbricon (Northern Italy: a 10-year survey

    Directory of Open Access Journals (Sweden)

    Andrea SQUARTINI

    2010-08-01

    Full Text Available Planktonic diatom fluctuations, their diversity and relationships with environmental variables were analyzed for ten consecutive years in Colbricon Superiore and Inferiore, two small high-mountain lakes located in the Paneveggio-Pale di S. Martino Natural Park (Trento, Italy offering the rare opportunity to study two lakes differing only by area and volume and being in this respect in a ratio of 2:1 and 3:1 respectively. The lakes were monitored and sampled monthly, during ten ice-free periods, from 1998 to 2007, to correlate water chemical and physical characteristics with the recorded diversity and abundance of planktonic diatoms. 55 taxa of Bacillariophyceae were found, among which Cyclotella spp., Tabellaria flocculosa and Fragilaria spp. were dominant. Both chemical data and diatom community composition are consistent with well buffered mesotrophic lakes. We found statistical evidence that the development of diatoms was strongly related to the variation of water temperature. Furthermore, several different signatures of the diatom-enviroment relationships arose between the two lakes as e.g., a negative correlation between diatom development and water transparency was occurring in the larger lake only. As a result, the average diatom density recorded over the 10 years period were 1.17 fold higher than in the lower lake which corresponds to a 1.65 fold higher biomass. A size-dependent tighter response of the phytoplankton to chemical parameters appears to operate in the smaller waterbody compared to the larger one.

  13. [Dentoalveolar trauma. Analysis of 4763 patients with 6237 injuries in 10 years].

    Science.gov (United States)

    Tuli, T; Hächl, O; Rasse, M; Kloss, F; Gassner, R

    2005-09-01

    The purpose of this study was to evaluate the overall place of dental trauma in facial injuries. This was a retrospective investigation based on the analysis of a large amount of dentoalveolar injuries over a 10-year period. Between 1991 and 2000, 4763 of 9543 patients suffering from oral and maxillofacial injuries, sustained dentoalveolar trauma. Records of 6237 different dental injury patterns were reviewed according to the five main injury mechanisms: age, sex, type of injury, cause of accident, and frequency of dentoalveolar trauma. They were statistically analyzed using frequency distribution, chi-square test, t-test, Mann-Whitney U test, Kolmogorov-Smirnov test, and logistic regression analysis. Household and play (2117), sports (1533), traffic accidents (438), acts of violence (426), and work-related accidents (201) were noted. A total of 4763 patients had 2988 subluxations, 2356 showed crown fractures, 444 had avulsions, 176 root fractures, 154 intrusions, and 119 patients suffered from concussions. This number of patients accounts for the prevalence of 49.9% for dentoalveolar trauma among all facial injuries. Only the analysis of a large number of injuries reveals the risk of suffering from dentoalveolar trauma. Due to this fact, preventive methods can be recommended and demanded more effectively.

  14. A 10 year survey of acaricide residues in beeswax analysed in Italy.

    Science.gov (United States)

    Boi, Michela; Serra, Giorgia; Colombo, Roberto; Lodesani, Marco; Massi, Sergio; Costa, Cecilia

    2016-07-01

    The aim of this work was to provide an overview of the prevalence and level of acaricides in beeswax used in Italy in the past 10 years by analysing 1319 beeswax samples processed by the certified laboratory of the Italian Bee Research Institute. The proportion of samples positive to at least one active ingredient decreased between 2005 and 2009 (from 69 to 32%) and then increased again between 2009 and 2014 (from 32 to 91%). This trend is in agreement with reports from beekeepers that the use of synthetic acaricides decreased in the second half of the past decade and increased after the beginning of the colony losses phenomenon. The active ingredient with the greatest overall proportion of positive samples was coumaphos (49%), followed by fluvalinate (38%) and chlorphenvinphos (25%). The indicator for amitraz, 2,4-dimethylphenylformamide (DMPF), was detected in a very small proportion of samples (6%), while residues of cymiazole were never found. In more than half of the analysed samples, residues of at least one active ingredient were detected. The mean levels of residues of all the considered active ingredients in the positive samples may represent a source of accumulation in beeswax and pose risks to honey bee health. © 2015 Society of Chemical Industry. © 2015 Society of Chemical Industry.

  15. The prognostic significance of molecular subtype for male breast cancer: a 10-year retrospective study.

    Science.gov (United States)

    Yu, Xing-Fei; Feng, Wei-Liang; Miao, Lu-Lu; Chen, Bo; Yang, Hong-Jian

    2013-10-01

    Male breast cancer (MBC) is rare. Molecular subtype has been utilized widely in female breast cancer. But the relationship between subtype and prognosis in MBC patients is still unknown. We aim to study the impact of molecular subtype on the prognosis of MBC. We identified MBC cases from 1990 to 2011 retrospectively; molecular subtype was assigned by immunohistochemistry. We compared overall survival in different subtypes by Kaplan-Meier method and COX proportional hazard regression model. 68 patients with MBC were included in analysis with 115 months of a median follow-up time. Comparing to non-luminal A (subtypes of Luminal B, HER2 over-express and Basal-like) group, patients with luminal A had a lower recurrent rate and better overall survival (10-year survival rate was 78.0% vs 67.0%, mean survival time 197.46 ± 12.22 months vs 146.51 ± 16.88 months, p < 0.05). Molecular subtype may have prognosis-predicting value for MBC. Copyright © 2013 Elsevier Ltd. All rights reserved.

  16. Epidemiologic Features and Outcomes of Caustic Ingestions; a 10-Year Cross-Sectional Study

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    Athena Alipour Faz

    2017-01-01

    Full Text Available Introduction: Caustic ingestions are among the most prevalent causes of toxic exposure. The present 10-year survey aimed to evaluate the epidemiologic features and outcomes of caustic ingestion cases presenting to emergency department.Methods: This is a retrospective cross-sectional study on patients who were admitted to a referral toxicology center during 2004 to 2014, following caustic ingestion. Baseline characteristics, presenting chief complaint, severity of mucosal injury, complications, imaging and laboratory findings as well as outcomes (need for ICU admission, need for surgery, mortality were recorded, reviewing patients’ medical profile, and analyzed using SPSS 22.Results: 348 patients with mean age of 37.76 ± 17.62 years were studied (55.6% male. The mean amount of ingested caustic agent was 106.69 ± 100.24 mL (59.2 % intentional. Intentional ingestions (p < 0.0001, acidic substance (p = 0.054, and higher volume of ingestion (p = 0.021 were significantly associated with higher severity of mucosal damage. 28 (8% cases had died, 53 (15.2% were admitted to ICU, and 115 (33% cases underwent surgery.Conclusion: It seems that, suicidal intention, higher grade of mucosal injury, higher volume of ingestion, lower level of consciousness, lower serum pH, and higher respiratory rate are among the most important predictors of need for ICU admission, need for surgery, and mortality.

  17. Minimum 10-year-results of extensively porous-coated stems in revision hip arthroplasty.

    Science.gov (United States)

    Paprosky, W G; Greidanus, N V; Antoniou, J

    1999-12-01

    Obtaining predictable, stable fixation of revision femoral implants is important for the long-term success of revision hip arthroplasty. The authors report on minimum 10 years clinical and radiographic followup of 170 patients with extensively coated cementless revision femoral components. With a range of followup of 10 to 16 years and a mean of 13.2 years, a survivorship of greater than 95% was reported. Clinically, the average Postel-D'Aubigne pain and walking score improved from a preoperative score of 5.4 points to 10.8 points postoperatively. Eighty-two percent of the hips had radiographic evidence of a bone-ingrown prosthesis and 13.9% had evidence of stable fibrous fixation. Four percent of stems were unstable as seen on radiographs. Six stems were revised to larger extensively coated stems and one stem is causing pain and is unstable but has yet to be revised. The overall mechanical failure rate was 4.1%. Stress shielding was greatest in patients with stems larger than 16.5 mm and in osteoporotic bone (Dorr Type C). Nine percent of patients had significant thigh pain including all of the patients with unstable stems. In the presence of bone loss in the proximal metaphyseal region of the femur, fixation of the femoral component is predictable when optimizing prosthetic-bone fit in the diaphyseal region of the femur using an extensively coated femoral component.

  18. Improvement in initial survival of spinal injuries: a 10-year audit.

    Science.gov (United States)

    Tan, H B; Sloan, J P; Barlow, I F

    2005-08-01

    A 10-year retrospective study of all spinal injuries presenting to the Leeds Teaching Hospitals between 1991 and 2001. The hospitals provide secondary care to a population of 750,000 and tertiary care to a population of 2-3 million. In total 1119 spinal injuries were studied. The overall survival rate was 89%. The commonest age group for presentation was 25-29 years with a secondary peak in the seventh decade, a mean overall of 43 years. 66% of injuries occurred in males. The commonest cause was a fall from a height (44%), with road traffic accidents (RTA) causing 43%. Pedestrians were most at risk within the road traffic group, making up 63% of cases. Isolated cervical spine injuries made up 37% of all cases. Cervical fractures were most associated with neurological injury (50%). Immediate survival has increased over the decade from 83% in 1991 to 93% in 2001. The probability of survival was significant at P = 0.006 and actual survival at P = 0.012 (Pearson correlation). The causal analysis has not been carried out but it is thought likely that improved quality of care is responsible.

  19. Natural history of heartburn: A 10-year population-based study

    Institute of Scientific and Technical Information of China (English)

    Linda Bjork Olafsdottir; Hallgrimur Gudjonsson; Heidur Hrund Jonsdottir; Bjarni Thjodleifsson

    2011-01-01

    AIM: To study the natural history and prevalence of heartburn at a 10-year interval, and to study the effect of heartburn on various symptoms and activities.METHODS: A population-based postal study was carried out. Questionnaires were mailed to the same ageand gender-stratified random sample of the Icelandic population (aged 18-75 years) in 1996 and again in 2006. Subjects were classified with heartburn if they reported heartburn in the preceding year and/or week,based on the definition of heartburn.RESULTS: Heartburn in the preceding year was reported in 42.8% (1996) and 44.2% (2006) of subjects, with a strong relationship between those who experienced heartburn in both years. Heartburn in the preceding week was diagnosed in 20.8%. There was a significant relationship between heartburn, dyspepsia and irritable bowel syndrome. Individuals with a body mass index (BMI)below or higher than normal weight were more likely to have heartburn. Heartburn caused by food or beverages was reported very often by 20.0% of subjects.CONCLUSION: Heartburn is a common and chronic condition. Subjects with a BMI below or higher than normal weight are more likely to experience heartburn.Heartburn has a great impact on daily activities, sleep and quality of life.

  20. Nanotechnology in glucose monitoring: advances and challenges in the last 10 years.

    Science.gov (United States)

    Scognamiglio, Viviana

    2013-09-15

    In the last decades, a wide multitude of research activity has been focused on the development of biosensors for glucose monitoring, devoted to overcome the challenges associated with smart analytical performances with commercial implications. Crucial issues still nowadays elude biosensors to enter the market, such as sensitivity, stability, miniaturisation, continuous and in situ monitoring in a complex matrix. A noteworthy tendency of biosensor technology is likely to push towards nanotechnology, which allows to reduce dimensions at the nanoscale, consenting the construction of arrays for high throughput analysis with the integration of microfluidics, and enhancing the performance of the biological components by using new nanomaterials. This review aims to highlight current trends in biosensors for glucose monitoring based on nanotechnology, reporting widespread representative examples of the recent approaches for nanobiosensors over the past 10 years. Progress in nanotechnology for the development of biosensing systems for blood glucose level monitoring will be discussed, in view of their design and construction on the bases of the new materials offered by nanotechnology.

  1. Stability and change in sexual orientation identity over a 10-year period in adulthood.

    Science.gov (United States)

    Mock, Steven E; Eibach, Richard P

    2012-06-01

    We examined reports of sexual orientation identity stability and change over a 10-year period drawing on data from the National Survey of Midlife Development in the United States (MIDUS I and II) and tested for three patterns: (1) heterosexual stability, (2) female sexual fluidity, and (3) bisexual fluidity. Fifty-four percent of the 2,560 participants were female and the average age was approximately 47 years. At Wave 1, 2,494 (97.42%) reported a heterosexual identity, 32 (1.25%) a homosexual identity, and 34 (1.33%) a bisexual identity and somewhat more than 2% reported a different sexual orientation identity at Wave 2. Although some support for each hypothesis was found, initial sexual orientation identity interacted with gender to predict a more complex pattern. For the sample as a whole, heterosexuality was the most stable identity. For women, bisexuality and homosexuality were equally unstable and significantly less stable than heterosexuality, suggesting that sexual orientation identity fluidity is a pattern that applies more to sexual minority women than heterosexual women. For men, heterosexuality and homosexuality were both relatively stable compared to bisexuality, which stood out as a particularly unstable identity. This pattern of results was consistent with previous findings and helps to address methodological limitations of earlier research by showing the characteristics of a population-based sample of heterosexual, homosexual, and bisexual identified men and women over time.

  2. A 10-year systematic review of HIV/AIDS mass communication campaigns: Have we made progress?

    Science.gov (United States)

    Noar, Seth M; Palmgreen, Philip; Chabot, Melissa; Dobransky, Nicole; Zimmerman, Rick S

    2009-01-01

    The purpose of the current study was to conduct a 10-year systematic review of HIV/AIDS mass communication campaigns focused on sexual behavior, HIV testing, or both (1998-2007) and to compare the results with the last comprehensive review of such campaigns, conducted by Myhre and Flora (2000). A comprehensive search strategy yielded 38 HIV/AIDS campaign evaluation articles published in peer-reviewed journals, representing 34 distinct campaign efforts conducted in 23 countries. The articles were coded on a variety of campaign design and evaluation dimensions by two independent coders. Results indicated that compared with the previous systematic review (1986-1998 period), campaigns increasingly have employed the following strategies: (1) targeted defined audiences developed through audience segmentation procedures; (2) designed campaign themes around behavior change (rather than knowledge change); (3) used behavioral theories; (4) achieved high message exposure; (5) used stronger research designs for outcome evaluation; and (6) included measures of behavior (or behavioral intentions) in outcome assessments. In addition, an examination of 10 campaign efforts that used more rigorous quasi-experimental designs revealed that the majority (8 of 10) demonstrated effects on behavior change or behavioral intentions. Despite these positive developments, most HIV/AIDS campaigns continue to use weak (i.e., preexperimental) outcome evaluation designs. Implications of these results for improved design, implementation, and evaluation of HIV/AIDS campaign efforts are discussed.

  3. Recurrent insulinoma in a 10-year-old boy with Down’s syndrome

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    Noman Ahmad

    2017-05-01

    Full Text Available An insulinoma is a rare tumour with an incidence of four cases per million per year in adults. The incidence in children is not established. There is limited literature available in children with insulinoma, and only one case is reported in association with Down’s syndrome in adults. Insulinoma diagnosis is frequently missed in adults as well as in children. The Whipple triad is the most striking feature although it has limited application in young children. Hypoglycaemia with elevated insulin, C-peptide and absent ketones is highly suggestive of hyperinsulinism. We present a case of 10-year-old boy with Down’s syndrome with recurrent insulinoma. He was initially misdiagnosed as having an adrenal insufficiency and developed cushingoid features and obesity secondary to hydrocortisone treatment and excessive sugar intake. The tumour was successfully localised in the head of the pancreas with an MRI and octreotide scan on first presentation. Medical treatment with diazoxide and octreotide could not achieve normal blood glucose levels. The insulinoma was laparoscopically enucleated and pathological examination confirmed a neuroendocrine tumour. Subsequently, he had complete resolution of symptoms. He had a recurrence after 2 years with frequent episodes of hypoglycaemia. The biochemical workup was suggestive of hyperinsulinism. MRI and PET scan confirmed the recurrence at the same site (head of the pancreas. He had an open laparotomy for insulinoma resection. The pathology was consistent with benign insulinoma, and subsequently, he had complete resolution of symptoms.

  4. Successful removal and reimplant of vagal nerve stimulator device after 10 years

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    Marco Giulioni

    2012-01-01

    Full Text Available The number of implanted vagal nerve stimulators is growing and the need for removal or revision of the devices will become even more frequent. A significant concern about Vagus Nerve Stimulation (VNS therapy is the presence of the spiral stimulating electrodes, wrapped around the nerve, once treatment is considered ineffective or is no longer desired. Our purpose is to demonstrate the feasibility of complete removal and replacement of the vagal nerve stimulator electrodes using microsurgical technique even after a long period, without damaging the nerve. We attempted removal and replacement of spiral stimulating electrodes from a patient who received a 10-year long VNS therapy for drug-resistant epilepsy. Our results indicate that the spiral electrodes may be safely removed from the vagus nerve, even after several years. The reversibility of lead implantation may enhance the attractiveness of VNS therapy. Furthermore, with a correct microsurgical technique, it is possible to respect the normal anatomy and functionality of vagal nerve and to reimplant a new VNS system with all its components, maintaining the same therapeutic efficacy after many years.

  5. Diagnosis and 10-year follow-up of a community-based hepatitis C cohort.

    Science.gov (United States)

    Yawn, Barbara P; Wollan, Peter; Gazzuola, Liliana; Kim, W Ray

    2002-02-01

    To determine the health care follow-up and treatment associated with physician-diagnosed hepatitis C (HCV) in a community-based population. We conducted a retrospective medical record review using records from all providers in Olmsted County, Minnesota. The study incorporated all Olmsted County residents with physician-diagnosed hepatitis C from 1990 through 1999. We assessed demographic and health status information as well as health services use in subjects with physician-diagnosed HCV. Physicians diagnosed hepatitis C in 355 subjects (219 men [62%], 136 women [38%]), mean age 43 years, in the 10-year period studied. About half of diagnoses (45%, n = 159) were confirmed with polymerase chain reaction or liver biopsies. Identified risk factors included IV drug use (50%), multiple sex partners (36%), and blood transfusion (30%). Follow-up assessment with aspartate aminotransferase/amino alanine transferase (AST/ALT) tests occurred in about half (49%) of subjects, while 202 subjects (60%) were referred for gastrointestinal (GI) specialist evaluation and 49 patients (14% of all, 25% of those referred to a GI specialist) had specific treatment for hepatitis C. Although well over half of patients (60%) had possible contraindications to HCV treatment, including heavy alcohol use, few were referred for chemical dependency therapy. In this community, follow-up and treatment related to HCV were limited. Attention to prevention of disease-accelerating co- infections was only modest. Referral or documented recommendations for treatment of alcoholism or heavy chronic alcohol ingestion were minimal.

  6. Lessons from high-throughput protein crystallization screening: 10 years of practical experience

    Science.gov (United States)

    JR, Luft; EH, Snell; GT, DeTitta

    2011-01-01

    Introduction X-ray crystallography provides the majority of our structural biological knowledge at a molecular level and in terms of pharmaceutical design is a valuable tool to accelerate discovery. It is the premier technique in the field, but its usefulness is significantly limited by the need to grow well-diffracting crystals. It is for this reason that high-throughput crystallization has become a key technology that has matured over the past 10 years through the field of structural genomics. Areas covered The authors describe their experiences in high-throughput crystallization screening in the context of structural genomics and the general biomedical community. They focus on the lessons learnt from the operation of a high-throughput crystallization screening laboratory, which to date has screened over 12,500 biological macromolecules. They also describe the approaches taken to maximize the success while minimizing the effort. Through this, the authors hope that the reader will gain an insight into the efficient design of a laboratory and protocols to accomplish high-throughput crystallization on a single-, multiuser-laboratory or industrial scale. Expert Opinion High-throughput crystallization screening is readily available but, despite the power of the crystallographic technique, getting crystals is still not a solved problem. High-throughput approaches can help when used skillfully; however, they still require human input in the detailed analysis and interpretation of results to be more successful. PMID:22646073

  7. Radiofrequency Ablation of Lung Cancer at Okayama University Hospital: A Review of 10 Years of Experience

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    Hiraki,Takao

    2011-10-01

    Full Text Available The application of radiofrequency ablation for the treatment of lung cancer by our group at Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences began in June 2001, and in the present report, we review our 10-year experience with this treatment modality at Okayama University Hospital. The local efficacy of radiofrequency ablation for the treatment of lung cancer depends on tumor size and the type of electrode used, but not on tumor type. An important factor for the prevention of local failure may be the acquisition of an adequate ablative margin. The combination of embolization and radiation therapy enhances the local efficacy. Local failure may be salvaged by repeating the radiofrequency ablation, particularly in small tumors. Survival rates after radiofrequency ablation are quite promising for patients with clinical stage I non-small cell lung cancer and pulmonary metastasis from colorectal cancer, hepatocellular carcinoma, and renal cell carcinoma. The complications caused by radiofrequency ablation can be treated conservatively in the majority of cases. However, attention should be paid to rare but serious complications. This review shows that radiofrequency ablation is a promising treatment for patients with lung cancer.

  8. Prevalence of red-green color vision deficiency (cvd among science students: a 10 years' survey

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    Arun V. Panat , M.Sc. M.Phil.

    2016-02-01

    Full Text Available Red-green Color vision deficiency (CVD has a high prevalence and is often a handicap in everyday life. The fact that most of the students do not know they have CVD due to non testing of color vision. All Science faculty students of the ASC Rahuri College in the age range of 17-19 were screened for Red-green CVD by using Ishihara test plates from 2001 to 2010. Thus total 654 males and 292 female students were screened during 10 years. The collected data were analyzed for frequency estimation among males and females and then estimating mating types by using the Hardy-Weinberg Principle. Frequency of color blindness in males was 0.303 and that in females 0.288. Predicted mating types show a higher contribution of carrier females, and homozygous color blinds than expected. Estimated normal mating type is only 35.35%. Prevalence of Red-green CVD was found considerably high among science students and specifically among females which is unusual. Mating types involving carrier females, colorblind females, and colorblind males together show a very high contribution than normal ones.

  9. Preoperative diagnosis of tubular adenoma of breast - 10 years of experience

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    Sanjay Sengupta

    2014-01-01

    Full Text Available Background: Tubular adenomas are rare benign neoplasms of female breast affecting women, predominantly of child-bearing age group. Definitive diagnosis of this tumor is usually achieved after histopathological study. Clinical, radiological, and even cytological features are often insufficient for accurate diagnosis. Aim: The aim of the present study was planned to analyze clinical and radiological features of histologically confirmed cases of tubular adenoma of breast to find out a clue for accurate preoperative cytological diagnosis. Materials and Methods: In our 10-year research program, all histologically confirmed tubular adenoma cases of breast were studied. Clinico-radio-cytological features, if available, were analyzed and tabulated. Results: Thirty-three cases of tubular adenoma of breast were studied. Radiological and cytological assessments are available for 12 and 26 cases, respectively. Tubular adenoma could be diagnosed in only two cases (7.7% by cytological assessment, but in none by radiological assessment. Conclusions: Clinico-cyto-radiological assessment could identify the benign nature of the tumors in most cases, but final confirmation was possible only after histopathological study.

  10. Paediatric head injury admissions over a 10-year period in a regional neurosurgical unit.

    Science.gov (United States)

    Phang, I; Mathieson, C; Sexton, I; Forsyth, S; Brown, J; St George, E J

    2012-08-01

    Traumatic brain injury is a leading cause of death and disability in childhood. A retrospective study of all paediatric head injuries admitted to the neurosurgical unit for the West of Scotland over a 10-year period was performed to assess the impact of the National Institute for Health and Clinical Excellence head injury guidelines on the admission rate and to determine the associated risk factors, causes, severity and outcomes of these injuries. There were 564 admissions between 1998 and 2007. The median age at presentation was nine years and two months. There was no change in the admission rate, injury mechanism or severity of head injury admitted over the period studied. A relationship was observed between the Scottish Index of Multiple Deprivation Score and the incidence of head injury (P = 0.05). Alcohol was reported as a causative factor in only a small number of cases, and moderate to severe head injuries were more commonly identified as a result of road traffic accidents.

  11. All-epiphyseal semitendinosus PCL reconstruction in a 10-year-old child.

    Science.gov (United States)

    Warme, Winston J; Mickelson, Dayne

    2010-01-01

    Tears of the posterior cruciate ligament (PCL) in pediatric patients, especially avulsions from its tibial insertion, are not frequently encountered by physicians. However, with an increasing incidence of ligamentous injuries to the knee in skeletally immature patients, orthopaedic surgeons will more frequently need to decide how best to manage a PCL injury in children with open physes. A 10-year-old boy sustained an avulsion of the PCL from its tibial insertion site after a bicycle motocross racing accident. He required a PCL reconstruction after failed conservative treatment and an unsuccessful attempt at primary repair. This successful physeal sparing reconstruction was accomplished using a modified method of femoral tunnel placement in combination with the tibial inlay technique. A magnetic resonance imaging was acquired 2 years postoperatively when physical examination demonstrated both legs of equal length, no varus or valgus deformity, and a normal posterior drawer examination. Four years after the reconstruction, he continues to bicycle motocross race while experiencing no further symptoms and complete restoration to his prior quality of life. The use of the tibial inlay technique together with the modified femoral tunnel location prevented transphyseal drilling while attaining a favorable anatomic placement of the graft while avoiding the "killer" turn associated with the transtibial approach. Level IV (Therapeutic Study).

  12. Ultrasonographic determination of the thyroid volume in 7- 10 years old children of Bushehr port 2007

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    Farzad Morad Haseli

    2009-02-01

    Full Text Available Background: Determination of thyroid volume using ultrasound has been recommended for monitoring public control of iodine deficiency programs in areas with mild iodine deficiency or with no iodine deficiency, instead of physical examination, in order to estimate the prevalence rate of goiter. The aim of this study was to determine the reference ranges of thyroid volume in Bushehr port. Methods: Thyroid volume of 1247 primary schoolchildren aged 7-10 years who were selected by probability proportionate to size method from rural and urban areas of Bushehr port was determined using ultrasonography. Medians and percentiles of thyroid volumes for age and body surface area were calculated for both genders. Results: The 97th percentiles of thyroid volume of Bushehr port schoolchildren according to age and sex were all lower than the corresponding sex-specific normative WHO reference values. Goiter prevalence was 1.68% according to WHO thyroid volume references for age in the studied population. The goiter prevalence according to age and body surface area-specific new normative WHO reference values were 7.13 and 7.17%, respectively. Conclusion: The 97th percentile for thyroid volume, calculated by ultrasonography in Bushehr port schoolchildren, were lower than the international WHO newly recommended reference values in all ages. Therefore, determination of a native reference value for estimating the prevalence rate of thyroid is highly recommended. According to ultrasonographically determined goiter prevalence, Bushehr is an iodine sufficient area.

  13. Mineralization and Transformation of Nitrogen Derived from Plant Materials in Soils over 10 Years

    Institute of Scientific and Technical Information of China (English)

    CHENGLI-LI; WENQI-XIAO

    1993-01-01

    Results of a 10-year decomposition experiment indicated that the annual mineralization rate of organic N in newly-formed humus varied with the type of original plant materials and the water regimes for decomposition,ranging from 0.028 to 0.074.The mineralization rate under waterlogged conditions was higher than that under upland conditions.The proportion of α-amino acid N in humus newly-formed under waterlogged conditions was slightly higher than that under upland conditions.It decreased gradually with time,while the proportion of nonhydrolyzable N showed no consistent trend,irrespective of the water regines for decomposition.The distribution of amino acids in humus newly-formed from different plant materials under various water regimes was quite similar with that in original plant materials,and only minor differences could be found among them.For example,in comparison to original plant materials,the newly-formed humus contained higher proportions of isoleucine,cysting,γ-amino-butyric acid and ornithine,and lower proportions of phenylalanine and proline.Moreover the proportion of phenylalanine was higher in the humus newly-fored under waterlogged conditions than that under upland conditions.

  14. Using Intelligent Techniques in Construction Project Cost Estimation: 10-Year Survey

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    Abdelrahman Osman Elfaki

    2014-01-01

    Full Text Available Cost estimation is the most important preliminary process in any construction project. Therefore, construction cost estimation has the lion’s share of the research effort in construction management. In this paper, we have analysed and studied proposals for construction cost estimation for the last 10 years. To implement this survey, we have proposed and applied a methodology that consists of two parts. The first part concerns data collection, for which we have chosen special journals as sources for the surveyed proposals. The second part concerns the analysis of the proposals. To analyse each proposal, the following four questions have been set. Which intelligent technique is used? How have data been collected? How are the results validated? And which construction cost estimation factors have been used? From the results of this survey, two main contributions have been produced. The first contribution is the defining of the research gap in this area, which has not been fully covered by previous proposals of construction cost estimation. The second contribution of this survey is the proposal and highlighting of future directions for forthcoming proposals, aimed ultimately at finding the optimal construction cost estimation. Moreover, we consider the second part of our methodology as one of our contributions in this paper. This methodology has been proposed as a standard benchmark for construction cost estimation proposals.

  15. Discharge against medical advice from Neonatal Intensive Care Unit: 10 years experience at a University Hospital

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    Hatim K Al-Turkistani

    2013-01-01

    Full Text Available Background: Discharging patients against medical advice is a problem of every age-group. However, because of their physiological vulnerability, the risk for the neonatal population is greater when discharged against medical advice (DAMA. This article is a study of the prevalence of the problem, the possible causes and/or risk factors. Materials and Methods: A retrospective review of 10 years of medical records of neonates discharged against medical advice from a Neonatal Intensive Care Unit (NICU at a university hospital. Results: The overall prevalence of DAMA was 1.6%. Most of the 51 infants who were taken out of hospital against medical advice (AMA were term (72.5% with a mean gestational age of 37.78 ± 2.5 weeks, of normal birth weight, with a mean of 2736 ± 661 g, Saudis (96%, those delivered vaginally (69%, and those that were provisionally diagnosed with transient tachypnea of newborn (TTN and/or query sepsis (49%. There was no difference between males and females (M/F = 1.2. There was an association between DAMA and the timing of DAMA (27.5% of DAMA at weekends and 67% of DAMA from May to October. Conclusion: DAMA of neonates is particularly critical. The causes and risk factors are many and difficult to predict. In addition to several other factors, its prevalence is influenced negatively by some socio-cultural beliefs.

  16. [The vocal rehabilitation with ESKA-Herrmann voice prosthesis. a report of a 10 years' experience].

    Science.gov (United States)

    Schuldt, T; Kramp, B; Dommerich, S

    2012-10-01

    ESKA-Herrmann voice prosthesis are available for almost 30 years and are used for the vocal rehabilitation of laryngectomees. Nevertheless there are no studies about this voice prosthesis. Especially because of the smaller external diameter of 5.5 mm differents to other voice prostheses may be expected.We analyzed the 10-year patient documentation in retrospect.67 patients (63 m/4f) got the ESKA-Herrmann voice prosthesis, which could be used with a mean lifetime of 131.4 days. The main reason of changing the prostheses were dislocation (34/119), loss by coughing (34/119) and the leakage around the prostheses. In total a good voice was documented in 83.9% of the prostheses.ESKA-Herrmann voice prostheses are an alternative to other prostheses. Because of the smaller external diameter the dislocation and loss of the prosthesis occur more often than other models. But it's the only model that allows a designated spontaneous closure of the trachea-esophageal fistula after prosthesis removal.

  17. Nasopharyngeal carcinoma in dermatomyositis patients: A 10-year retrospective review in Hospital Selayang, Malaysia

    Science.gov (United States)

    Teoh, J.W.; Yunus, Razif M.; Hassan, Faridah; Ghazali, Norazmi; Abidin, Zainal A.Z.

    2014-01-01

    Aim The objective of our review is to investigate the association between dermatomyositis patients and nasopharyngeal carcinoma (NPC) together with the clinical presentation of the patients and their management in otorhinolaryngology. Background NPC is a malignant disease with good prognosis on early diagnosis. However, the relationship between the dermatomyositis and NPC and its management is not well defined. Materials and methods A 10-year retrospective review of case records of 21 dermatomyositis patients seen in Otorhinolaryngology Department of Hospital Selayang from January 2000 to November 2010. Results These patients ranged from 19 to 74 years old and a total of 8 (38%) out of 21 adults with dermatomyositis were detected to have malignancy. Five out of 8 patients had NPC (62.5%). The mean age of patients with NPC and dermatomyositis was 48 years. NPC is diagnosed in 4 out of 5 patients (80%) in the first year of diagnosis of dermatomyositis. The clinical findings of the examination of nasopharynx ranged from hyperemia to exophytic nasopharyngeal mass. Histologically, it is only related to NPC of WHO types II and III. Conclusions There is a strong relationship between dermatomyositis and malignancy, especially NPC. Clinicians should have a high index of suspicion for malignancy in all dermatomyositis patients. Rigid nasoendoscopies and biopsies, serum Epstein–Barr viral capsid IgA antibody and imaging studies are helpful in detecting NPC in dermatomyositis patients. PMID:25184058

  18. Bacterial Infection Complicating Varicella Infection: A 10-Year Review of Hospitalized Children

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    Golda Milo-Manson

    1993-01-01

    Full Text Available An increased incidence of Streptococci pyogenes (group A streptococcus [GAS] infections and rheumatic fever has been reported over the past decade. The present study was conducted to determine whether a similar increase in such infections was observed after varicella, an infection previously shown to be associated with a high incidence of streptococcal infections. The charts of all children admitted with chickenpox to the Hospital for Sick Children in Toronto, Ontario from January 1, 1980 to December 31, 1989 were reviewed. Immunocompromised children and those hospitalized for another reason who had an incidental diagnosis of chickenpox were excluded. Twenty-five cases with bacterial infection complicating chickenpox were compared with 103 patients without secondary infection. No statistically significant differences were observed for age, gender, duration of illness prior to hospitalization or duration of hospitalization in the two groups. GAS was the most frequent isolate in the cases, followed by Staphylococcus aureus, Escherichia coli and Haemophilus influenzae. The types of infection were significantly different for GAS compared with other organisms, with a predominance of skin infections in the former group (χ2 analysis, P<0.05. No increase in the incidence of GAS infections was observed over time. This study confirms the importance of GAS infections in patients with varicella, but no increase was observed in hospitalized children during the 10-year study period.

  19. Pleomorphic Adenoma of the Palate in a 10-year-old Child: A Case Report

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    SH Tabatabaei

    2016-03-01

    Full Text Available Salivary gland tumors  are  uncommon  within  children and  when  they do arise,  they  mainly  affect  the  major  salivary glands. Minor salivary gland  tumors  are  rare  in  children, which are  responsible for less than 10% of all the cases. Pleomorphic adenoma is the most common tumor of  the salivary glands in the all ages. A 10-year-old boy referred to the dentistry clinic with a swelling in the palate of adjacent unerupted right maxillary second molar. In sampling by curettage, clinical pathologist reported ameloblastoma. The patient was referred to the dental school of Shahid Sadoughi University of Medical Sciences for consultation. Second  microscopic analysis showed a benign pleomorphic adenoma that was confirmed by special staining periodic acid-Schiff (PAS, immunohistochemistry cytokeratin(CK, and S100 staining. Pleomorphic adenoma of minor salivary gland of children should be considered as a differential diagnosis of intraoral swelling in the palate.

  20. [Evidence-based quality assessment of 10-year orthodontic clinical trials in 4 major dental journals].

    Science.gov (United States)

    Sun, Yan-nan; Lei, Fei-fei; Cao, Yan-li; Fu, Min-kui

    2010-02-01

    To assess the quality of orthodontic clinical trials published in 4 major dental journals in the past 10 years and establish the reference standard for orthodontic clinical trials and quality control of dental journals. All the clinical trials published in Chinese Journal of Stomatology, West China Journal of Stomatology, Journal of Practice Stomatology and Chinese Journal of Orthodontics from 1999 to 2008 were searched. The demographic information of the papers was extracted and the quality of the clinical trials according to the consolidated standards of reporting trials (CONSORT) was assessed. Four hundred and ninety-four clinical trials were retrieved, and 21.3% (105/494) of them were supported by grants. For the study design, only 26.1% (129/494) were prospective studies, and 3.8% (19/494) were randomized clinical trials. It was hard to evaluate precisely due to the lack of information about the details of the study designs. For the randomized clinical trials, the lack of details for randomization, allocation concealment, blinding and intention to treat compromised the quality. The general quality of clinical trials in orthodontics is poor. It needs to be improved both in the clinical study design and the paper writing.

  1. Unusual case of West Nile Virus flaccid paralysis in a 10-year-old child.

    Science.gov (United States)

    Thabet, Farouq I; Servinsky, Sarah E; Naz, Fareeha; Kovas, Teresa E; Raghib, Timur O

    2013-05-01

    West Nile virus infection is asymptomatic in most cases. West Nile virus neuroinvasive disease includes encephalitis, meningitis, and/or acute flaccid paralysis. In children, acute flaccid paralysis as the solo presentation of West Nile virus disease is rare. It develops abruptly and progresses rapidly early in the disease course. We report on a 10-year-old child who presented with a slowly progressive left leg flaccid paralysis over 4 weeks. He tested positive for West Nile virus in both blood and cerebrospinal fluid. Spinal MRI showed enhancement of the ventral nerve roots. This was also supported by electrophysiological studies. One week after the plateauing of his left leg paralysis, he was readmitted to the hospital with left hand weakness. Complete recovery of his recurrent weakness was observed after prompt 5-day course of intravenous immunoglobulin G therapy. However, no improvement was noticed in the left foot drop. To our knowledge, this is the first case report of West Nile virus disease in children presented with a slowly progressive flaccid paralysis, and a recurrent weakness recovered after intravenous immunoglobulin G administration.

  2. Bonneville Power Administration, Office of Engineering 10-Year Plan, 1992-2001 : Draft.

    Energy Technology Data Exchange (ETDEWEB)

    United States. Bonneville Power Administration. Office of Engineering.

    1992-05-01

    For over 50 years, the Bonneville Power Administration (BPA) has evolved to supply electric power to more than 170 customer utilities and direct service industries across 14,800 miles of high voltage transmission lines. BPA`s Office of Engineering provides the planning, development, and engineering for the required expansion, upgrade, and replacement of the transmission system. The purpose of this 10-Year Plan is to present strategies to maintain a reliable energy delivery system within changing public, business, technological, and environmental climates. The issues and trends discussed in this document and our strategies for addressing them provide the background for the Office of Engineering programs and projects. With a budget in the hundreds of millions annually and increasing public concern, we welcome the opportunity to communicate with our customers. In addition to the factors, trends and issues described in this document are two appendices containing project costs and program and staffing levels. These figures are preliminary with estimates current as of May 13, 1992.

  3. Bonneville Power Administration, Office of Engineering 10-Year Plan, 1992-2001 : Draft.

    Energy Technology Data Exchange (ETDEWEB)

    United States. Bonneville Power Administration. Office of Engineering.

    1992-05-01

    For over 50 years, the Bonneville Power Administration (BPA) has evolved to supply electric power to more than 170 customer utilities and direct service industries across 14,800 miles of high voltage transmission lines. BPA's Office of Engineering provides the planning, development, and engineering for the required expansion, upgrade, and replacement of the transmission system. The purpose of this 10-Year Plan is to present strategies to maintain a reliable energy delivery system within changing public, business, technological, and environmental climates. The issues and trends discussed in this document and our strategies for addressing them provide the background for the Office of Engineering programs and projects. With a budget in the hundreds of millions annually and increasing public concern, we welcome the opportunity to communicate with our customers. In addition to the factors, trends and issues described in this document are two appendices containing project costs and program and staffing levels. These figures are preliminary with estimates current as of May 13, 1992.

  4. Flat affect and social functioning: a 10 year follow-up study of first episode psychosis patients.

    Science.gov (United States)

    Evensen, Julie; Røssberg, Jan Ivar; Barder, Helene; Haahr, Ulrik; Hegelstad, Wenche Ten Velden; Joa, Inge; Johannessen, Jan Olav; Larsen, T K; Melle, Ingrid; Opjordsmoen, Stein; Rund, Bjørn Rishovd; Simonsen, Erik; Vaglum, Per; McGlashan, Thomas; Friis, Svein

    2012-08-01

    Affective flattening has been described as enduring, but long term follow-up studies of first episode psychosis patients are lacking. The aim of this study was to follow the symptom development of flat affect (FA), over a 10 year follow-up period, with focus on prevalence, predictors and outcome factors including social functioning. Three-hundred-and-one patients with FEP were included at baseline, 186 participated in the 10 year follow-up. These were followed on PANSS item N1 (FA) from baseline through 5 follow-up assessments over 10 years. Patients were grouped as having never-present, improving, deteriorating, fluctuating or enduring FA. The groups were compared on baseline variables, variables at 10 year follow-up, and social functioning throughout the follow-up period. Twenty nine percent never displayed FA, 66% had improving, deteriorating or fluctuating FA, while 5% of patients had enduring FA. Premorbid social function predicted enduring FA. The patients with enduring, fluctuating and deteriorating FA did poorer on all outcome variables, including remission and recovery rates. The enduring FA group did significantly poorer in social functioning over the 10 year period. FA is expressed at some point of time in the majority of FEP patients in a 10 year follow-up period, and appears more fluctuant than expected from the relevant literature. FA is associated with poorer outcome after 10 years, and enduring FA to poorer social function at all points of assessment. Copyright © 2012 Elsevier B.V. All rights reserved.

  5. Stunted at 10 Years. Linear Growth Trajectories and Stunting from Birth to Pre-Adolescence in a Rural Bangladeshi Cohort.

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    Pernilla Svefors

    Full Text Available Few studies in low-income settings analyse linear growth trajectories from foetal life to pre-adolescence. The aim of this study is to describe linear growth and stunting from birth to 10 years in rural Bangladesh and to analyse whether maternal and environmental determinants at conception are associated with linear growth throughout childhood and stunting at 10 years.Pregnant women participating in the MINIMat trial were identified in early pregnancy and a birth cohort (n = 1054 was followed with 19 growth measurements from birth to 10 years. Analyses of baseline predictors and mean height-for-age Z-scores (HAZ over time were modelled using GLMM. Logistic regression analysis was used to investigate the associations between baseline predictors and stunting (HAZ<-2 at 10 years. HAZ decreased to 2 years, followed by an increase up to 10 years, while the average height-for-age difference in cm (HAD to the WHO reference median continued to increase up to 10 years. Prevalence of stunting was highest at 2 years (50% decreasing to 29% at 10 years. Maternal height, maternal educational level and season of conception were all independent predictors of HAZ from birth to pre-adolescence (p<0.001 and stunting at 10 years. The highest probability to be stunted at 10 years was for children born by short mothers (<147.5 cm (ORadj 2.93, 95% CI: 2.06-4.20, mothers with no education (ORadj 1.74, 95% CI 1.17-2.81 or those conceived in the pre-monsoon season (ORadj 1.94, 95% CI 1.37-2.77.Height growth trajectories and prevalence of stunting in pre-adolescence showed strong intergenerational associations, social differentials, and environmental influence from foetal life. Targeting women before and during pregnancy is needed for the prevention of impaired child growth.

  6. Development and validation of a 10-year-old child ligamentous cervical spine finite element model.

    Science.gov (United States)

    Dong, Liqiang; Li, Guangyao; Mao, Haojie; Marek, Stanley; Yang, King H

    2013-12-01

    Although a number of finite element (FE) adult cervical spine models have been developed to understand the injury mechanisms of the neck in automotive related crash scenarios, there have been fewer efforts to develop a child neck model. In this study, a 10-year-old ligamentous cervical spine FE model was developed for application in the improvement of pediatric safety related to motor vehicle crashes. The model geometry was obtained from medical scans and meshed using a multi-block approach. Appropriate properties based on review of literature in conjunction with scaling were assigned to different parts of the model. Child tensile force-deformation data in three segments, Occipital-C2 (C0-C2), C4-C5 and C6-C7, were used to validate the cervical spine model and predict failure forces and displacements. Design of computer experiments was performed to determine failure properties for intervertebral discs and ligaments needed to set up the FE model. The model-predicted ultimate displacements and forces were within the experimental range. The cervical spine FE model was validated in flexion and extension against the child experimental data in three segments, C0-C2, C4-C5 and C6-C7. Other model predictions were found to be consistent with the experimental responses scaled from adult data. The whole cervical spine model was also validated in tension, flexion and extension against the child experimental data. This study provided methods for developing a child ligamentous cervical spine FE model and to predict soft tissue failures in tension.

  7. 10 years with Planet Earth essence in the primary school children drawings

    Science.gov (United States)

    D'Addezio, Giuliana

    2016-04-01

    "10 years with Planet Earth" is the title of the 2016 INGV calendar for primary schools representing the review of a project conceived as support and complement of 15 years long INGV dissemination activities with schools. We realized 10 calendars together with and for primary schools, every year with a subject related to a World in constant evolution. Earthquakes, volcanic eruptions, tsunami waves, magnetic storms and other phenomena are manifestations of the complexity and dynamicity, which began more than four billion years ago and never halted. Since the Earth originated to the first presence of water, life and oxygen, the Cambrian explosion of species, the domain of dinosaurs, the great extinctions and glaciations, the surface of our planet experiences continents collisions, mountains and oceans formation and life forms emerging and disappearing. Every year we have launched a competition asking children to send drawings on themes chosen to stimulate learning about Earth Sciences and Planet Earth dynamics. We intended to raise awareness on issues as water resources availability, protection against natural disasters and control of environmental degradation. For each competition, we chose the most significant drawings to be included in the yearly calendar about the Earth. The authors of drawings were awarded by scientists, journalists, artists and science communicators and even by a minister. Besides the competitions, these drawings depict their own impressions and reflections, providing an opportunity to illustrate the children's point of view. From drawings and texts arise a great consideration and respect for the Planet, raising hopes that similar initiatives can contribute to increase the knowledge of the Earth and of the fragile human ecosystem in the hearts and minds of future active citizens. The project was made possible thanks to the teachers and to the wonderful students of more than 200 schools that sent about 10,000 drawings that have intrigued

  8. Estrogen receptor testing and 10-year mortality from breast cancer: A model for determining testing strategy

    Directory of Open Access Journals (Sweden)

    Christopher Naugler

    2012-01-01

    Full Text Available Background: The use of adjuvant tamoxifen therapy in the treatment of estrogen receptor (ER expressing breast carcinomas represents a major advance in personalized cancer treatment. Because there is no benefit (and indeed there is increased morbidity and mortality associated with the use of tamoxifen therapy in ER-negative breast cancer, its use is restricted to women with ER expressing cancers. However, correctly classifying cancers as ER positive or negative has been challenging given the high reported false negative test rates for ER expression in surgical specimens. In this paper I model practice recommendations using published information from clinical trials to address the question of whether there is a false negative test rate above which it is more efficacious to forgo ER testing and instead treat all patients with tamoxifen regardless of ER test results. Methods: I used data from randomized clinical trials to model two different hypothetical treatment strategies: (1 the current strategy of treating only ER positive women with tamoxifen and (2 an alternative strategy where all women are treated with tamoxifen regardless of ER test results. The variables used in the model are literature-derived survival rates of the different combinations of ER positivity and treatment with tamoxifen, varying true ER positivity rates and varying false negative ER testing rates. The outcome variable was hypothetical 10-year survival. Results: The model predicted that there will be a range of true ER rates and false negative test rates above which it would be more efficacious to treat all women with breast cancer with tamoxifen and forgo ER testing. This situation occurred with high true positive ER rates and false negative ER test rates in the range of 20-30%. Conclusions: It is hoped that this model will provide an example of the potential importance of diagnostic error on clinical outcomes and furthermore will give an example of how the effect of that

  9. Difficulty Managing Medications and Finances in Older Adults: A 10-year Cohort Study.

    Science.gov (United States)

    Bleijenberg, Nienke; Smith, Alexander K; Lee, Sei J; Cenzer, Irena Stijacic; Boscardin, John W; Covinsky, Kenneth E

    2017-07-01

    Difficulty managing medicines and finances becomes increasingly common with advanced age, and compromises the ability to live safely and independently. Remarkably little is known how often this occurs. To provide population-based estimates of the risk of developing incident difficulty managing medications and finances in older adults. A prospective cohort study. The Health and Retirement Study (HRS), a nationally representative study of older adults. 9,434 participants aged 65 and older who did not need help in managing medications or managing finances in 2002. Follow-up assessments occurred every 2 years until 2012. The primary outcomes were time to difficulty managing medications and time to difficulty managing finances. Risk factors such as demographics, comorbidities, functional status, and cognitive status were assessed at baseline. Hazard models that considered the competing risk of death were used to estimate both the cumulative incidence of developing difficulty managing medications and finances and to identify potential risk factors. Analyses were adjusted for age, gender, race, marital status, wealth and education. The 10 years incidence of difficulty increased markedly with age, ranging from 10.3% (95% CI 9.3-11.6) for managing medications and 23.1% (95% CI 21.6-24.7) for managing finances in those aged 65-69, to 38.2% (95% CI 33.4-43.5) for medicines and 69% (95% CI 63.7-74.3) for finances in those over age 85. Women had a higher probability of developing difficulty managing medications and managing finances than men. This study highlights the importance of preparing older adults for the likelihood they will need assistance with managing their medicines and finances as the risk for having difficulty with these activities over time is substantial. © 2017, Copyright the Authors Journal compilation © 2017, The American Geriatrics Society.

  10. Bullying and attention-deficit- hyperactivity disorder in 10-year-olds in a Swedish community.

    Science.gov (United States)

    Holmberg, Kirsten; Hjern, Anders

    2008-02-01

    The association of attention-deficit-hyperactivity disorder (ADHD) with bullying in the peer group in school was studied in an entire population of 577 fourth graders (10-year-olds) in one municipality in Stockholm, Sweden. The schoolchildren were screened for ADHD in a two-step procedure that included Conners'ratings of behavioural problems: teacher and parent interviews in a first step; and a clinical assessment in the second. Information about bullying was collected from the children themselves in a classroom questionnaire. Five-hundred and sixteen children (89.4%; 252 females, 264 males), for whom there was information from all data sources, were included in the study population. Conners'ratings that were collected from parents early in first grade were available for 382 of these children. Hypotheses were tested by multivariate analyses with adjustment for sex and parental education. Pervasive ADHD was diagnosed in 9.5% (95% confidence interval [CI] 5.6-12.8) of the males and 1.6% (CI 0.1-3.1) of the females. ADHD was associated with bullying other students (adjusted odds ratios (OR) 3.8 [CI 2.0-7.2]) as well as being bullied (often, OR 10.8 [CI 4.0-29.0]; sometimes, OR 2.9 [CI 1.5-5.7]). Bullying other students in fourth grade was associated with high scores in parental reports of behavioural problems at entry into first grade, suggesting a causal link to the ADHD syndrome. Being bullied, on the other hand, was not linked to behavioural problems at school entry. This study demonstrates a connection between ADHD and bullying in the peer group at school. Evaluation and treatment strategies for ADHD need to include assessment and effective interventions for bullying. Evaluation of ADHD should be considered in children involved in bullying.

  11. Reactivation of intestinal CMV in a renal transplant patient after 10 years from the transplant

    Directory of Open Access Journals (Sweden)

    Maria Landi

    2013-04-01

    Full Text Available Introduction.We analyzed the clinical case of a 51 years old man, kidney transplanted on December 2002. On April 2011, he had acute rectal bleeding, renal chronic rejection (creatinine 2.9 mg/dl, Hgb 8.7 g/dl, positive anti-CMV antibodies (IgG. A colonoscopy showed diverticulosis of the rectum associated with deepithelialisation. The patient was treated with maintenance immunosuppressive post-transplant therapy. On June 2011, the colonoscopy showed a stenosing lesion of the sigmoid colon, and blood sampling and intestinal biopsy were performed to search Cytomegalovirus (CMV DNA by PCR. Methods. The presence of CMV-DNA was sought by automatic extractor QIACUBE, using QIAamp DNA BLOOD Mini Kit (Qiagen for whole blood and QIAamp DNA Mini Kit (Qiagen for biopsy.The extracted DNA was then amplified by Real Time PCR using Q-CMV RealTime Complete Kit (Nanogen, on instrument Applied Biosystems 7300. Results. At disease onset the viral load in whole blood was 208000 Geq/ml, and biopsy was positive. Antiviral therapy with Ganciclovir led to the negativity of the viral load and remission of symptoms. Conclusions. The clinical case described presented a reactivation of CMV infection in the intestine after more than 10 years from kidney transplantation, while the highest incidence of CMV reactivation usually occurs during the first year. In our opinion, the reactivation can be traced to long-term immunosuppressive therapy (maintenance posttransplant therapy in combination with a state of inflammation of the intestinal mucosa. In fact, patients with IBD treated with steroid drugs, in particular the group of refractory to therapy and thus have a recovery of the inflammatory process, are exposed to reactivation of CMV with intestinal localization.

  12. Pattern of salivary gland tumors in Manipur, India: A 10 year study

    Directory of Open Access Journals (Sweden)

    Rajesh Singh Laishram

    2013-01-01

    Full Text Available Background: Salivary gland lesions, especially the neoplastic lesions constitute a highly heterogeneous histopathologic group. Several studies have reported a significant difference in the global distribution of salivary gland tumors, but no formal study has been carried out in this part of the globe. Objectives: To document the pattern of various salivary gland tumors in Manipur, a state in North Eastern India. Materials and Methods: This is a 10 years (2002-2011 retrospective study of all salivary gland specimens received at our referral teaching hospital in Manipur, India. All the histopathology slides of salivary gland specimens during the study period were reviewed and clinical details were obtained from the archives. Restaining of slides and fresh sections of tissue blocks were performed whenever required. Data thus collected were analyzed. Results: A total of 104 cases of salivary gland lesions were studied during the study period. Age ranged from 5 years to 78 years with an overall slight female preponderance (M:F = 1:1.08. Parotid (56.65% was the commonest gland involved followed by submandibular gland (31.73%.Neoplastic lesions comprised of 78 (75% cases and non-neoplastic lesions constituted 25% (26 cases. Among the neoplastic lesions, benign lesions (53.85% predominated over malignant lesions (21.15%. Pleomorphic adenoma was the commonest benign neoplastic lesion and mucoepidermoid carcinoma was the commonest malignant tumor. Chronic sialadenitis was the predominant lesion in the non-neoplastic group. Conclusion: The principal site for salivary gland tumors was the parotid gland and pleomorphic adenoma outnumbered all the other tumors. Females are more affected in the malignant group.

  13. Ciguatera fish poisoning in Hong Kong--a 10-year perspective on the class of ciguatoxins.

    Science.gov (United States)

    Wong, Chun-Kwan; Hung, Patricia; Lo, Janice Y C

    2014-08-01

    The present study used liquid chromatography-tandem mass spectrometry (LC-MS/MS) to investigate retrospectively ciguatoxin (CTX)-positive samples as determined by mouse bioassay (MBA) in the past 10 years in Hong Kong. The results showed that Pacific CTXs (P-CTX-1, -2 and -3) were the most commonly observed toxins found in the samples, indicating Pacific Ocean areas as the most important origin of ciguatera fish poisoning. Clinical diagnosis from ciguatera patients also revealed the predominance of neurological illnesses in most cases, supporting intoxication of Pacific origin. This study demonstrated the ability of laboratory analysis to identify and quantify Pacific CTXs in suspected fish samples, so as to support the clinical diagnosis of ciguatera. Comparative analysis (Student's t-test and Spearman's rank correlation analysis) on the two CTX detection methods showed approximate linearity for overall P-CTXs (P-CTX-1, -2 and -3)/P-CTX-1 alone as derived by LC-MS/MS and total toxicity levels (P-CTX-1 equivalent) as determined by MBA. The LC-MS/MS method coupled with the rapid extraction method could allow the detection of trace amount of CTXs at levels below the clinically relevant limit, 0.1 ppb P-CTX-1 in fish flesh. For practical application, the adoption of a two-tiered approach for testing, chemical analysis by LC-MS/MS for toxic fish screening, coupled with biological assay by MBA for final toxicity confirmation, was proposed for first-line screening of CTX in potentially contaminated fish samples in the market, with an aim to minimizing the use of laboratory mice and at the same time providing reasonably effective means for routine analysis.

  14. Marine anthropogenic litter on British beaches: A 10-year nationwide assessment using citizen science data.

    Science.gov (United States)

    Nelms, S E; Coombes, C; Foster, L C; Galloway, T S; Godley, B J; Lindeque, P K; Witt, M J

    2017-02-01

    Growing evidence suggests that anthropogenic litter, particularly plastic, represents a highly pervasive and persistent threat to global marine ecosystems. Multinational research is progressing to characterise its sources, distribution and abundance so that interventions aimed at reducing future inputs and clearing extant litter can be developed. Citizen science projects, whereby members of the public gather information, offer a low-cost method of collecting large volumes of data with considerable temporal and spatial coverage. Furthermore, such projects raise awareness of environmental issues and can lead to positive changes in behaviours and attitudes. We present data collected over a decade (2005-2014 inclusive) by Marine Conservation Society (MCS) volunteers during beach litter surveys carried along the British coastline, with the aim of increasing knowledge on the composition, spatial distribution and temporal trends of coastal debris. Unlike many citizen science projects, the MCS beach litter survey programme gathers information on the number of volunteers, duration of surveys and distances covered. This comprehensive information provides an opportunity to standardise data for variation in sampling effort among surveys, enhancing the value of outputs and robustness of findings. We found that plastic is the main constituent of anthropogenic litter on British beaches and the majority of traceable items originate from land-based sources, such as public littering. We identify the coast of the Western English Channel and Celtic Sea as experiencing the highest relative litter levels. Increasing trends over the 10-year time period were detected for a number of individual item categories, yet no statistically significant change in total (effort-corrected) litter was detected. We discuss the limitations of the dataset and make recommendations for future work. The study demonstrates the value of citizen science data in providing insights that would otherwise not be

  15. Etiology of precocious puberty, 10 years study in Endocrine Reserch Centre (Firouzgar, Tehran

    Directory of Open Access Journals (Sweden)

    Fatemeh Safari

    2012-01-01

    Full Text Available Background: Precocious puberty, as early physical development and low final height might lead to psychosocial problems.Objective: To evaluate etiology and clinical feature of precocious puberty in a cohort of Iranian children.Materials and Methods: In this case-series study, 44 girls and 8 boys with precocious puberty referred to Endocrine Reserch Centre (Firouzgar, Institute of Endocrinology and Metabolism (Hemmat Campus, were examined in a 10 years period of time. Results: Mean age of girls and boys was 7.43±1.4 years and 5.8±2.1 years respectively. Most of the patients fell within the age category of 7-7.9 years old (40.9% for girls and 50% for boys. Patients, concerning etiology of precocious puberty were classified in three categories: 42.6% of patients had central precocious puberty (CPP, including idiopathic CPP (87.5% and neurogenic CPP (12.5%. 23.3% of patients had peripheral precocious puberty (PPP, including congenital adrenal hyperplasia (CAH (42.8%, ovarian cysts (28.4%, McCune-Albright syndrome (14.2% and adrenal carcinoma (14.2%. 34.1% of girls and 25% of boys had normal variant puberty including premature thelarche (57%, premature adrenarche (38% as well as premature menarche (4.7%l. Conclusion: The most common etiology of precocious puberty in girls was idiopathic central precocious puberty and premature thelarche, while in boys they were neurogenic central precocious puberty and CAH. Therefore precocious puberty in girls is usually benign. In boys, CNS anomalies should first be considered in the differential diagnosis of CPP. Therefore brain Magnetic Resonance Imaging (MRI is mandatory in all cases.

  16. Parkinson disease, 10 years after its genetic revolution: multiple clues to a complex disorder.

    Science.gov (United States)

    Klein, Christine; Schlossmacher, Michael G

    2007-11-27

    Over the last 10 years, an unprecedented number of scientific reports have been published that relate to the pathogenesis of parkinsonism. Since the discovery in 1997 of the first heritable form of parkinsonism that could be linked to a mutation in a single gene, SNCA, many more genetic leads have followed (Parkin, DJ-1, PINK1, LRRK2, to name a few); these have provided us with many molecular clues to better explore the etiology of parkinsonism and have led to the dismantling of many previously held dogmas about Parkinson disease (PD). Epidemiologic studies have delineated an array of environmental modulators of susceptibility to parkinsonism, which can now be examined in the context of gene expression. Furthermore, in vivo imaging data and postmortem results have generated concepts that greatly expanded our appreciation for the phenotypic spectrum of parkinsonism from its presymptomatic to advanced stages. With this plethora of new information emerged the picture of a complex syndrome that raises many questions: How many forms of classic parkinsonism/Parkinson disease(s) are there? Where does the disease begin? What causes late-onset, "idiopathic" PD? What are the caveats related to genetic testing? What is the role of Lewy bodies? What will be the best disease model to accommodate the now known genetic and environmental contributors to parkinsonism? What will be the ideal markers and targets for earlier diagnosis and cause-directed therapy? In the following article we highlight some of the burning issues surrounding the understanding of classic parkinsonism, a complex puzzle of genes, environment, and an aging host.

  17. Future prospect 2012-2025 - How will our business change for the next 10 years -

    Science.gov (United States)

    Tanaka, Sakae

    2013-04-01

    The purpose of this lecture is to discuss about the "Future". How our business will change in the next 10 years? I believe the key is 3 mega-trends "Sustainability", "Cloud Computing" and "Life Innovation". With the development of social environment, the required business will change, too. The future would be invisible if you shut yourself up in your single industry. It is important to see various business fields horizontally, and recognize various key changes stereoscopically such as demographics, economy, technology, sense of value and lifestyle, when you develop mid-and-long term strategy. "Cloud" is silent, but the revolution of personal computing. It will bring the drastic changes in every industry. It will make "voice" and "moving image" possible to use as the interface to access your computer. Cloud computing will also make the client device more diversified and spread the application range widely. 15 years ago, the term "IT" was equivalent to "personal computer". Recently, it rather means to use smartphone and tablet device. In the next several years, TV and car-navigation system will be connected to broadband and it will become a part of personal computing. The meaning of personal computing is changing essentially year by year. In near future, the universe of computing will expand to the energy, medical and health-care, and agriculture etc. It passed only 20 years since we use "Computer" in a full scale operation. Recently, computer has start understanding our few words and talking in babble like a baby. The history of computing has just started.

  18. Stability of symptom patterns in Australian Gulf War veterans: 10-year longitudinal study.

    Science.gov (United States)

    Gwini, S M; Kelsall, H L; Sim, M R; Ikin, J F; McFarlane, A C; Forbes, A B

    2016-03-01

    Previously we established that symptoms reported by 1990-1991 Gulf War veterans were correlated and exhibited a pattern with 3 factors (psychophysiological distress, somatic distress and arthroneuromuscular distress), and this pattern was similar to that observed in a military comparison group. In this follow-up study, we examined whether the patterns of symptomatology have changed over time. Using data on 56 symptoms that was collected in 2000-2003 (wave 1) and 2011-2012 (wave 2) from an Australian cohort of Gulf War veterans (veterans) and a military comparison group, exploratory factor analysis was conducted and Tucker's Congruence Coefficient (TCC) was used to determine factor structure similarity across study groups and waves. The results showed that the 3 factors observed at wave 1 were still present at wave 2, and factor structures across study groups and study waves were fairly similar, with TCC ranging 0.86-0.92. Veterans consistently reported more symptoms across all 3 factors. Veterans' symptomatology specific to psychophysiological distress increased between waves 1 and 2 (ratio of means 1.15; 95% CI 1.07 to 1.25) but psychophysiological distress symptomatology was constant in the comparison group (ratio of means 0.97; 95% CI 0.89 to 1.06). Somatic and arthroneuromuscular distress symptomatology significantly increased over time for both study groups, although at a similar rate. While the symptom groupings (measured by the 3 factors) remained unchanged at 10 years of follow-up, and remained comparable between Gulf War and comparison group, symptomatology continued to be elevated in Gulf War veterans than in the comparison group, and was most evident for psychophysiological distress. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  19. Healthcare-associated Pneumonia: Clinical Features and Retrospective Analysis Over 10 Years

    Directory of Open Access Journals (Sweden)

    Fei Qi

    2015-01-01

    Full Text Available Background: Healthcare-associated pneumonia (HCAP is associated with drug-resistant pathogens and high mortality, and there is no clear evidence that this is due to inappropriate antibiotic therapy. This study was to elucidate the clinical features, pathogens, therapy, and outcomes of HCAP, and to clarify the risk factors for drug-resistant pathogens and prognosis. Methods: Retrospective observational study among hospitalized patients with HCAP over 10 years. The primary outcome was 30-day all-cause hospital mortality after admission. Demographics (age, gender, clinical features, and comorbidities, dates of admission, discharge and/or death, hospitalization costs, microbiological results, chest imaging studies, and CURB-65 were analyzed. Antibiotics, admission to Intensive Care Unit (ICU, mechanical ventilation, and pneumonia prognosis were recorded. Patients were dichotomized based on CURB-65 (low- vs. high-risk. Results: Among 612 patients (mean age of 70.7 years, 88.4% had at least one comorbidity. Commonly detected pathogens were Acinetobacter baumannii, Pseudomonas aeruginosa, and coagulase-negative staphylococci. Initial monotherapy with β-lactam antibiotics was the most common initial therapy (50%. Mean age, length of stay, hospitalization expenses, ICU admission, mechanical ventilation use, malignancies, and detection rate for P. aeruginosa, and Staphylococcus aureus were higher in the high-risk group compared with the low-risk group. CURB-65 ≥3, malignancies, and mechanical ventilation were associated with an increased mortality. Logistic regression analysis showed that cerebrovascular diseases and being bedridden were independent risk factors for HCAP. Conclusion: Initial treatment of HCAP with broad-spectrum antibiotics could be an appropriate approach. CURB-65 ≥3, malignancies, and mechanical ventilation may result in an increased mortality.

  20. Incidence of Alzheimer′s disease in India: A 10 years follow-up study

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    P S Mathuranath

    2012-01-01

    Full Text Available Objective: To determine overall and age-specific incidence rates of Alzheimer′s disease (AD in a southern Indian province, Kerala. Materials and Methods: A 10-year (2001-2011 prospective epidemiologic study of community residing subjects aged ≥55 years at enrollment. The catchment area included four urban and semi-urban regions of Trivandrum city in Kerala, India, was selected to provide a range of demographic and socioeconomic representation. Cognitive and functional ability screening were done at baseline and 24-month follow-up assessments. Consensus diagnostic procedures were done using the Diagnostic and Statistical Manual of Mental Disorders, 4 th edition (DSM-IV, and the National Institute of Neurological and Communicative Disorders and Stroke - Alzheimer′s Disease and Related Disorders Association (NINDS-ADRDA criteria for the diagnosis of dementia and AD. Results: Among the 1066 eligible participants who were cognitively normal at baseline, 104 developed dementia (98 with AD over a follow-up period of 8.1 years. The incidence rates per 1000 person-years for AD was 11.67 (95% CI: 10.9-12.4 for those aged ≥55 years and higher for those aged ≥65 years (15.54, 95% CI: 14.6-16.5. In those aged ≥65 years, the world age standardized incidence rate was 21.61 per 100,000, and standardized against the age distribution for the year 2000 U.S. Census, the age-adjusted incidence rate was 9.19 (95% CI: 9.03-9.35 per 1000 person-years. Incidence rate of AD increased significantly and proportionately with increasing age. Conclusion: These are the first AD incidence rates to be reported from southern India. The incidence rates appear to be much higher than that reported from rural north India, comparable with that reported from China, and marginally lower than that reported from the western world.

  1. Increased plasma dopamine in patients presenting with the pseudopheochromocytoma quandary: retrospective analysis of 10 years' experience.

    Science.gov (United States)

    Kuchel, O

    1998-10-01

    A retrospective analysis was made to determine alternative diagnoses in patients with predominantly hypertensive episodes who were suspected of having pheochromocytoma but in whom this diagnosis was eliminated. Analysis of a random university hospital population referred over a period of 10 years. Episodic clinical presentations of pheochromocytoma symptoms combined with a comparison of baseline and episodic radioenzymatically determined levels of plasma free norepinephrine and epinephrine were examined, together with prospective levels of plasma free and sulfated dopamine. Out of 63 patients presenting with episodes of palpitations, headaches, flushing, sweating and hyperventilation (associated with hypertension in 49 patients, with hypotension in six patients and with alternating hyper- and hypotension in eight patients), 14 were diagnosed as having idiopathic hypovolemia, nine as having mastocytosis, nine as having an adrenal tumor, four as having neurogenic hypertension and one each with cocaine abuse and reninoma. Both baseline and symptomatic levels of plasma free norepinephrine and epinephrine remained within physiological limits (exceeding them moderately in baroreceptor dysfunction only), but all subgroups had a mean episodic increase over baseline in plasma dopamine sulfate (mean+/-SEM 16.7+/-5.9 to 53.2+/-19 pmol/ml; P pheochromocytoma in hemodynamic instability and frequent flushing formed a heterogeneous group, with plasma norepinephrine and epinephrine usually within physiological limits but an overall mean threefold increase in dopamine sulfate concentrations. With the various diagnoses of idiopathic hypovolemia, mastocytosis, neurogenic, secondary hypertension and cocaine abuse eliminated as a cause of pheochromocytoma-like symptoms, at least half of these patients still had unexplained, predominantly emotionally or proprioreceptive stimulation-provoked, bouts of hypertension. Sympathetic arousal dominated by an increase in dopamine sulfate without

  2. Association between dietary lead intake and 10-year mortality among Chinese adults.

    Science.gov (United States)

    Shi, Zumin; Zhen, Shiqi; Orsini, Nicola; Zhou, Yonglin; Zhou, Yijing; Liu, Jianghong; Taylor, Anne W

    2017-05-01

    Blood lead level is associated with increased risk of mortality, but dietary lead exposure and mortality, particularly with cancer, has not been studied in the general population. The objective of the study was to assess the association between lead intake and 10-year mortality among 2832 Chinese adults. Food intake was measured by 3-day weighed food record in 2002. We documented 184 deaths (63 cancer deaths and 70 cardiovascular disease (CVD) deaths) during 27,742 person-years of follow-up. Dietary lead intake was positively associated with cancer and all-cause mortality. Across quartiles of lead intake, hazard ratios (HRs) for cancer mortality were 1.00, 0.80 (0.33-1.92), 1.52 (0.65-3.56), and 3.00 (1.06-8.44) (p for trend 0.028). HRs for all-cause mortality were 1.00, 1.28 (0.83-1.98), 1.24 (0.78-1.97), and 2.24 (1.28-3.94) (p for trend 0.011). Each 30 μg/day increase of lead intake was associated with 25% (95% CI 3-52%) increase of all-cause mortality. There was an interaction between lead intake and hypertension in relation to CVD mortality (p for interaction 0.003): HRs conferred by every 30 μg/day of lead intake were 1.57 (0.98-2.52) and 1.06 (0.81-1.39) among those with or without hypertension. Dietary lead intake was positively related to cancer and all-cause mortality.

  3. Impact of antifungal prescription on relative distribution and susceptibility of Candida spp. - Trends over 10 years.

    Science.gov (United States)

    Bailly, Sébastien; Maubon, Danièle; Fournier, Pierre; Pelloux, Hervé; Schwebel, Carole; Chapuis, Claire; Foroni, Luc; Cornet, Muriel; Timsit, Jean-François

    2016-01-01

    The incidence of Candida spp. infections is worrisome, particularly in critically ill patients. Previous reports suggested that increasing use of antifungal therapy might affect resistance profiles of invasive strains. The study objective was to describe the distribution resistance profile of Candida spp. strains, and to correlate it with antifungal consumptions within one ICU. Antifungal drug consumption was measured as the number of defined daily doses per 1000 hospital days. The distribution of Candida spp. over a 10 year period 2004-2013 and the MICs of antifungal drugs over 2007-2013 were determined. Time series analyses were performed. Of 2403 identified Candida spp. from 5360 patients, Candida albicans predominated (53.1%), followed by Candida glabrata (16.2%), Candida parapsilosis (7.9%) and Candida tropicalis (7.5%). C. parapsilosis increased from 5.7% in 2004 to 8.4% in 2013 (P = 0.02). The increase in caspofungin use is correlated with the increase in caspofungin MICs of C. parapsilosis (P = 0.01), C. glabrata (P = 0.001) and C. albicans (P = 0.02). Polyenes consumption correlated with an increase in amphotericin B MICs of C. glabrata (P = 0.04). Previous history of antifungal prescription within an ICU influences Candida species distribution and susceptibility profile to antifungal agents. The significant selective pressure exerted by caspofungin and amphotericin B on C. glabrata is a concern. Copyright © 2015 The British Infection Association. Published by Elsevier Ltd. All rights reserved.

  4. Flap prefabrication in the head and neck: a 10-year experience.

    Science.gov (United States)

    Pribaz, J J; Fine, N; Orgill, D P

    1999-03-01

    Tissue neovascularized by implanting a vascular pedicle can be transferred as a "prefabricated flap" based on the blood flow through the implanted pedicle. This technique potentially allows any defined tissue volume to be transferred to any specified recipient site, greatly expanding the armamentarium of reconstructive options. During the past 10 years, 17 flaps were prefabricated and 15 flaps were transferred successfully in 12 patients. Tissue expanders were used as an aid in 11 flaps. Seven flaps were prefabricated at a distant site and later transferred using microsurgical techniques. Ten flaps were prefabricated near the recipient site by either transposition of a local vascular pedicle or the microvascular transfer of a distant vascular pedicle. The prefabricated flaps were subsequently transferred as island pedicle flaps. These local vascular pedicles can be re-used to transfer additional neovascularized tissues. Common pedicles used for neovascularization included the descending branch of the lateral femoral circumflex, superficial temporal, radial, and thoracodorsal pedicles. Most flaps developed transient venous congestion that resolved in 36 to 48 hours. Venous congestion could be reduced by incorporating a native superficial vein into the design of the flap or by extending the prefabrication time from 6 weeks to several months. Placing a Gore-Tex sleeve around the proximal pedicle allowed for much easier pedicle dissection at the time of transfer. Prefabricated flaps allow the transfer of moderate-sized units of thin tissue to recipient sites throughout the body. They have been particularly useful in patients recovering from extensive burn injury on whom thin donor sites are limited.

  5. 10 years after rio-concepts on the contribution of chemistry to a sustainable development.

    Science.gov (United States)

    Eissen, Marco; Metzger, Jürgen O; Schmidt, Eberhard; Schneidewind, Uwe

    2002-02-01

    The principles of the United Nations Conference on Environment and Development (UNCED), held in June 1992 in Rio de Janeiro, and Agenda 21, the comprehensive plan of action for the 21st century, adopted 10 years ago by more than 170 governments, address the pressing problems of today and also aim at preparing the world for the challenges of this century. The conservation and management of resources for development are the main focus of interest, to which the sciences will have to make a considerable contribution. Natural, economic, and social sciences will have to be integrated in order to achieve this aim. In their future programs, the associations of the chemical industries in Europe, Japan, and the USA have explicitly accepted their obligation to foster a sustainable development. In this review we investigate innovations in chemistry exemplarily for such a development with regard to their ecological, economical, and social dimensions from an integrated and interdisciplinary perspective. Since base chemicals are produced in large quantities and important product lines are synthesized from them, their resource-saving production is especially important for a sustainable development. This concept has been shown, amongst others, by the example of the syntheses of propylene oxide and adipic acid. In the long run, renewable resources that are catalytically processed could replace fossil raw materials. Separation methods existing today must be improved considerably to lower material and energy consumption. Chemistry might become the pioneer of an innovative energy technique. The design of chemical products should make possible a sustainable processing and recycling and should prevent their bio-accumulation. Methods and criteria to assess their contribution to a sustainable development are necessary. The time taken to introduce the new more sustainable processes and products has to be diminished by linking their development with operational innovation management and with

  6. Childhood hospitalisation for otitis media in Western Australia: A 10-year retrospective analysis

    Directory of Open Access Journals (Sweden)

    Nicholas Liu

    2016-04-01

    Full Text Available Background The aim of this study was to assess the prevalence of hospitalisation for otitis media across the different risk indicators for Western Australian children (less than 15 years old over a 10-year period. Method This retrospective population-based study used the deidentified detailed data of children under the age of 15 years, hospitalised for otitis media (OM, as determined by principal diagnosis (ICD-10AM and obtained from the Western Australian (WA Hospital Morbidity Dataset for 10 financial years from 1999–2000 to 2008–2009. Various risk indicators, including age, gender, Indigenous status, insurance status, hospital area, hospital type, and length of stay were also analysed. Results Out of 26,294 cases of in-hospital care, Indigenous children comprised 4.7 per cent (n=1,226, while the non-Indigenous children comprised 95.3 per cent (n=25,068. The majority of the children, nearly 98.8 per cent, were admitted for chronic OM. The children were grouped into three age groups, namely, 0–4 years, 5–9 years, and 10–14 years. Nearly two-thirds of all cases were in the 0–4-year age group. Significantly more non-Indigenous (51 per cent than Indigenous children (2 per cent had private health insurance. The hospitalisation rates were directly proportional between the number of Indigenous children living in the area and the increasing remoteness of the area along with greater socioeconomic disadvantage. There were 24 per cent more cases from very remote areas compared to highly accessible areas, and there were 60 per cent more cases from the most disadvantaged socioeconomic category, compared with the least disadvantaged category, for Indigenous children. Conclusion These data depict the variations in prevalence of otitis media hospitalisations within the community, as affected by various risk indicators.

  7. Retinopathy of prematurity: results from 10 years in a single neonatal intensive care unit

    Directory of Open Access Journals (Sweden)

    Inês Coutinho

    2017-01-01

    Full Text Available Introduction: Retinopathy of prematurity (ROP is a vasoproliferative disorder of the retina of preterm newborns and is an important and preventable cause of visual impairment in childhood. This study aimed to assess the incidence and main risk factors associated with the development of ROP in the last 10 years at Hospital Prof. Doutor Fernando Fonseca in Lisbon, Portugal.Methods: Observational and retrospective study conducted between 2005 and 2014 at Hospital Prof. Doctor Fernando Fonseca. The study included newborns of gestational age < 32 weeks. We analyzed maternal, prenatal and neonatal factors associated with the development of ROP. Statistical analysis were performed with Statistical Package for Social Sciences (SPSS® software. Univariate and multivariate analyses were performed and a multiple logistic regression model was carried out with a significance level α = 0.05.Results: 527 premature infants with a gestational age < 32 weeks were studied, of which 165 developed ROP. 60 of these patients needed treatment. In the univariate analysis, the risk factors for the development of ROP were maternal infection in pregnancy, low birth weight, low gestational age, low Apgar score at 5 minutes, need for oxygen therapy until the 28th day of life, a high score on the CRIB and SNAPPE2 scales, use of surfactant, respiratory distress syndrome, persistence of patent ductus arteriosus, peri-intraventricular hemorrhage and neonatal sepsis. In the multiple logistic regression analysis, risk factors for ROP were the presence of neonatal sepsis, respiratory distress syndrome, persistence of patent ductus arteriosus and a high score on the neonatal SNAPPE2 scale.Conclusions: We found a ROP incidence rate of 31.3%, with risk factors similar to those observed in other studies.

  8. Healthcare-associated Pneumonia: Clinical Features and Retrospective Analysis Over 10 Years

    Institute of Scientific and Technical Information of China (English)

    Fei Qi; Guo-Xin Zhang; Dan-Yang She; Zhi-Xin Liang; Ren-Tao Wang; Zhen Yang; Liang-An Chen

    2015-01-01

    Background:Healthcare-associated pneumonia (HCAP) is associated with drug-resistant pathogens and high mortality,and there is no clear evidence that this is due to inappropriate antibiotic therapy.This study was to elucidate the clinical features,pathogens,therapy,and outcomes of HCAP,and to clarify the risk factors for drug-resistant pathogens and prognosis.Methods:Retrospective observational study among hospitalized patients with HCAP over 10 years.The primary outcome was 30-day all-cause hospital mortality after admission.Demographics (age,gender,clinical features,and comorbidities),dates of admission,discharge and/or death,hospitalization costs,microbiological results,chest imaging studies,and CURB-65 were analyzed.Antibiotics,admission to Intensive Care Unit (ICU),mechanical ventilation,and pneumonia prognosis were recorded.Patients were dichotomized based on CURB-65 (low-vs.high-risk).Results:Among 612 patients (mean age of 70.7 years),88.4% had at least one comorbidity.Commonly detected pathogens were Acinetobacter baumannii,Pseudomonas aeruginosa,and coagulase-negative staphylococci.Initial monotherapy with β-lactam antibiotics was the most common initial therapy (50%).Mean age,length of stay,hospitalization expenses,ICU admission,mechanical ventilation use,malignancies,and detection rate for P.aeruginosa,and Staphylococcus aureus were higher in the high-risk group compared with the low-risk group.CURB-65 ≥3,malignancies,and mechanical ventilation were associated with an increased mortality.Logistic regression analysis showed that cerebrovascular diseases and being bedridden were independent risk factors for HCAR.Conclusion:Initial treatment of HCAP with broad-spectrum antibiotics could be an appropriate approach.CURB-65 ≥3,malignancies,and mechanical ventilation may result in an increased mortality.

  9. Percutaneous radiofrequency ablation of renal tumors in high-risk patients: 10 years' experience.

    Science.gov (United States)

    Alguersuari, A; Mateos, A; Falcó, J; Criado, E; Fortuño, J R; Guitart, J

    2016-01-01

    To retrospectively evaluate the efficacy and safety of percutaneous radiofrequency ablation (RFA) done to treat renal tumors in patients with high surgical risk or with the risk of developing multiple renal tumors in the medium term at our center over a period of 10 years. Between 2005 and 2015, we used RFA to treat 89 T1a or T1b tumors in 87 patients (mean age, 73.7±10.87 years) with high surgical risk. We excluded patients treated with radiofrequency and embolization or microwave ablation. The tumors treated were clear cell carcinomas (43.6%), papillary renal carcinomas (17.2%), chromophobe renal cell carcinomas (10.3%), cystic tumors (2.2%), and an angiomyolipoma (1.1%). The mean size of the tumors was 2.6cm. Computed tomography and/or ultrasonography were used to guide the procedure. We analyzed the relation between the efficacy of the procedure and patients' age, the type of needle, the source of the patients, the size and location of the tumor, and the number of sessions required to achieve ablation. We recorded all complications. The RFA procedure was completed in all patients. The mean follow-up period was 32.1 months. The efficacy was 93.7%. A single session was sufficient in 87.5% of patients; 8% required two sessions and 4.5% required three sessions. The only factor associated with worse efficacy was the size of the tumor (p=0.03). The rate of complications was 5.6%. RFA is efficacious and safe, with results comparable to those reported in the literature. Copyright © 2016 SERAM. Publicado por Elsevier España, S.L.U. All rights reserved.

  10. Changes in cytomegalovirus seroprevalence in pregnant Japanese women-a 10-year single center study.

    Science.gov (United States)

    Taniguchi, Kosuke; Watanabe, Noriyoshi; Sato, Anna; Jwa, Seung Chik; Suzuki, Tomo; Yamanobe, Yuji; Sago, Haruhiko; Kozuka, Kazuto

    2014-03-01

    Human cytomegalovirus (CMV) causes congenital infections during pregnancy, and seroepidemiological data are important for estimating the risk of infection. However, only a few reports of CMV seroprevalence exist for pregnant Japanese women. The purpose of this study was to assess CMV seroprevalence in pregnant Japanese women. This cross-sectional study involved pregnant Japanese women who delivered from 2003 to 2012 at our hospital (n=15,616). Among these women, 14,099 (90.3%) underwent tests for the presence of CMV IgG. Those with an equivocal test result were excluded (n=195) from this analysis, leaving a study sample of 13,904 Japanese pregnant women. The prevalence of CMV IgG was also assessed by calendar year, age, and parity. The overall CMV IgG prevalence rate was 66.0%. CMV IgG prevalence significantly decreased over the course of 10 years from 2003 to 2012 (from 69.9% in 2003 to 65.2% in 2012) (p40 years were 1.66 (95%CI: 1.25-2.20), 1.20 (95%CI: 1.07-1.35), 1.16 (95%CI: 1.07-1.26), and 1.44 (95%CI: 1.28-1.62), respectively, compared to women aged 30-35 years. Adjusted odds ratios for CMV IgG positivity for a parity of 1, 2, and ≥3 were 1.14 (95%CI: 1.06-1.23), 1.52 (95%CI: 1.32-1.77), and 2.54 (95%CI: 2.69-3.84), respectively, compared to nulliparous women. We found that 34% of pregnant Japanese women were susceptible to CMV infection. Calendar year, maternal age, and parity were significantly associated with changes in CMV seroprevalence among this population. Copyright © 2014 Elsevier B.V. All rights reserved.

  11. Meckel′s diverticulum in paediatric practice on Crete (Greece: A 10-year review

    Directory of Open Access Journals (Sweden)

    Evangelos Blevrakis

    2011-01-01

    Full Text Available Background: Although Meckel′s diverticulum (MD is the most prevalent congenital abnormality of the gastrointestinal tract, it has varied presentations and often becomes a diagnostic challenge. The purpose of this study was to review the diverse presentations of MD, record the epidemiologic features for Crete and review the detection techniques and the treatment options. Patients and Methods: This was a review of the records of all children who underwent surgery for MD in the department of Paediatric Surgery of the University Hospital of Crete (Greece between January 1999 and January 2009. Result: A total of 45 patients (32 male and 13 female aged 1 to 13 years (median 10 years with a diagnosis of MD were retrospectively reviewed. The collected data were analysed, looking at age, gender, clinical features, investigations, histopathological findings and surgical interventions. In 25 patients, MD was an incidental finding at laparotomy because of appendicitis. The remaining 20 patients were symptomatic and presented with various clinical features. Nine patients (19.9% had clinical features of peritonitis; of these, three had perforated MD and six had Meckel′s diverticulitis at laparotomy. Four patients were diagnosed with intestinal obstruction. Seven patients (15.5% presented with lower gastrointestinal bleeding. Ultrasound scans revealed intussusception in three patients, requiring open reduction. The remaining four patients with bleeding per rectum underwent a Meckel′s Tc99 scan that showed a positive tracer. Conclusion: All patients with MD underwent Meckel′s diverticulectomy with appendicectomy. MD has an incidence of approximately 1 to 2% in our population. It is necessary to maintain a high index of suspicion in the in the diagnosis of MD paediatric age group because it can be easily misdiagnosed.

  12. Reaching Spanish-speaking smokers online: a 10-year worldwide research program

    Science.gov (United States)

    Muñoz, Ricardo Felipe; Chen, Ken; Bunge, Eduardo Liniers; Bravin, Julia Isabela; Shaughnessy, Elizabeth Annelly; Pérez-Stable, Eliseo Joaquín

    2014-01-01

    Objective To describe a 10-year proof-of-concept smoking cessation research program evaluating the reach of online health interventions throughout the Americas. Methods Recruitment occurred from 2002–2011, primarily using Google.com AdWords. Over 6 million smokers from the Americas entered keywords related to smoking cessation; 57 882 smokers (15 912 English speakers and 41 970 Spanish speakers) were recruited into online self-help automated intervention studies. To examine disparities in utilization of methods to quit smoking, cessation aids used by English speakers and Spanish speakers were compared. To determine whether online interventions reduce disparities, abstinence rates were also compared. Finally, the reach of the intervention was illustrated for three large Spanish-speaking countries of the Americas—Argentina, Mexico, and Peru—and the United States of America. Results Few participants had utilized other methods to stop smoking before coming to the Internet site; most reported using no previous smoking cessation aids: 69.2% of Spanish speakers versus 51.8% of English speakers (P < 0.01). The most used method was nicotine gum, 13.9%. Nicotine dependence levels were similar to those reported for in-person smoking cessation trials. Overall observed quit rate for English speakers was 38.1% and for Spanish speakers, 37.0%; quit rates in which participants with missing data were considered to be smoking were 11.1% and 10.6%, respectively. Neither comparison was significantly different. Conclusions The systematic use of evidence-based Internet interventions for health problems could have a broad impact throughout the Americas, at little or no cost to individuals or to ministries of health. PMID:25211569

  13. Basic Facts of Breast Cancer in Korea in 2014: The 10-Year Overall Survival Progress.

    Science.gov (United States)

    Park, Eun Hwa; Min, Sun Young; Kim, Zisun; Yoon, Chan Seok; Jung, Kyu-Won; Nam, Seok Jin; Oh, Se Jeong; Lee, Seeyoun; Park, Byeong-Woo; Lim, Woosung; Hur, Min Hee

    2017-03-01

    We, the Korean Breast Cancer Society (KBCS), present the facts and the trends of breast cancer in Korea in 2014. Data on the total number of newly diagnosed patients was obtained from the Korea Central Cancer Registry database, other data were collected from the KBCS online registry database, and the overall survival data of patients were updated from Statistics Korea. A total of 21,484 female patients were newly diagnosed with breast cancer in 2014. The crude incidence rate and the age-standardized incidence rate (ASR) of breast cancer in female patients, including carcinoma in situ, were 83.4 cases and 63.9 cases per 100,000 women, respectively. The ASR showed an annual increase of 6.1% from 1999 to 2014; however, although the increase of the ASR had slowed since 2008, the incidence rate itself continuously increased. The proportion of early breast cancer increased consistently, and the pathological features changed accordingly. While breast-conserving surgery was mainly performed, the proportion of total mastectomy was slightly increased. The total number of breast reconstruction surgeries increased rapidly. The 5-year and 10-year overall survival rates for all stages of breast cancer patients were 91.2% and 84.8%, respectively. The overall survival rate of Korean patients with breast cancer was extremely high, compared with other developed countries. Thus, we consider that the clinical characteristics of breast cancer have changed over the past decade. A nationwide registry data will contribute to a better understanding of the characteristics of breast cancer in Korea.

  14. From SARS to MERS: 10 years of research on highly pathogenic human coronaviruses.

    Science.gov (United States)

    Hilgenfeld, Rolf; Peiris, Malik

    2013-10-01

    This article introduces a series of invited papers in Antiviral Research marking the 10th anniversary of the outbreak of severe acute respiratory syndrome (SARS), caused by a novel coronavirus that emerged in southern China in late 2002. Until that time, coronaviruses had not been recognized as agents causing severe disease in humans, hence, the emergence of the SARS-CoV came as a complete surprise. Research during the past ten years has revealed the existence of a diverse pool of coronaviruses circulating among various bat species and other animals, suggesting that further introductions of highly pathogenic coronaviruses into the human population are not merely probable, but inevitable. The recent emergence of another coronavirus causing severe disease, Middle East respiratory syndrome (MERS), in humans, has made it clear that coronaviruses pose a major threat to human health, and that more research is urgently needed to elucidate their replication mechanisms, identify potential drug targets, and develop effective countermeasures. In this series, experts in many different aspects of coronavirus replication and disease will provide authoritative, up-to-date reviews of the following topics: - clinical management and infection control of SARS; - reservoir hosts of coronaviruses; - receptor recognition and cross-species transmission of SARS-CoV; - SARS-CoV evasion of innate immune responses; - structures and functions of individual coronaviral proteins; - anti-coronavirus drug discovery and development; and - the public health legacy of the SARS outbreak. Each article will be identified in the last line of its abstract as belonging to the series "From SARS to MERS: 10years of research on highly pathogenic human coronaviruses." Copyright © 2013 Elsevier B.V. All rights reserved.

  15. Performance of pfa concrete in a marine environment 10-year results

    Energy Technology Data Exchange (ETDEWEB)

    M.D.A. Thomas; J.D. Matthews [University of New Brunswick, Fredericton, NB (Canada). Dept. of Civil Engineering

    2004-01-01

    Steel reinforced 100100300 mm concrete prisms, with nominal strength grades C25, C35 and C45 and different pfa levels (0 50%), were exposed to various curing treatments during the first 28 days prior to exposure in the tidal zone of the BRE marine exposure site. Chloride concentration profiles and rebar weight losses had previously been measured on specimens exposed for 1, 2 and 4 years and this paper reports the results of similar measurements after 10 years exposure. Chloride profiles were also measured for specimens after 1 and 28 days immersion in seawater under laboratory conditions. Pfa concretes showed substantially increased resistance to the penetration of chlorides compared with control Portland cement (PC) concrete specimens. The improved resistance of the pfa concrete to the penetration of chlorides resulted in reduced corrosion of steel bars imbedded in the concrete. Threshold chloride levels for corrosion, estimated from relationships between steel weight loss and chloride content at the location of the steel, were found to decrease with increasing pfa content. Chloride concentration profiles after 28 days of immersion in seawater showed that considerable chloride penetration occurred during this period due to sorption (capillary suction) of the seawater into the unsaturated specimens. This results in a significant error in diffusion coefficients calculated from the concentration profile using the standard solution to Fick's second law. The error may be substantial for pfa concretes where chlorides penetrating due to sorption immediately after exposure may outweigh subsequent diffusion during continued seawater exposure. The performance of the concretes, particularly the PC concretes, in this programme is considered in the light of current and new British Standard recommendations for concrete exposed to marine tidal conditions.

  16. Spinal cord injury in patients with ankylosing spondylitis: a 10-year review.

    Science.gov (United States)

    Thumbikat, Pradeep; Hariharan, Ramaswamy P; Ravichandran, Ganapathiraju; McClelland, Martin R; Mathew, Kidangalil M

    2007-12-15

    Retrospective study. To evaluate the clinical and functional outcomes in patients with spinal cord injury (SCI) and preexisting ankylosing spondylitis (AS). AS alters the strength and biomechanical properties of the spine that renders it susceptible to fracture with minimal trauma. Neurologic involvement is common and outcomes largely depend on the early recognition and appropriate management. A 10-year review (1996-2005) was carried out to identify all patients admitted with SCI associated with AS. The cause of injury, prehospital and emergency management, definitive treatment of fracture, final neurology, and functional outcomes were ascertained. Reasons for neurologic deterioration were determined. Eighteen patients were identified. In 15 patients, the injury resulted from trauma (fall 14, road accident 1) and in 3 the SCI followed spinal surgical interventions. Twelve of the 15 patients with traumatic injuries were able to walk immediately after the fall but subsequently deteriorated for various reasons. Spinal epidural hematomas developed in 3 patients (2 traumatic, 1 spinal intervention). The fractures were managed surgically in 3 patients, halo jacket was used in 2, and the remainder were managed expectantly on traction. Four patients died before discharge, 4 were able to walk with an aid at discharge, and the others were wheel chair dependent. Neurologic deficits were often subtle on initial presentation, resulting in many injuries being missed because of a low index of suspicion and poor visualization of lower cervical fractures on conventional radiographs. Extension of the ankylosed kyphotic cervical spine during conventional immobilization or for radiologic procedures resulted in neurologic deficits. Patients with an ankylosed cervical spine are normally unable to see the ceiling lying supine because of cervicothoracic kyphosis and use pillows to support their head. Cervical spine alignment in a similar flexed position is essential during immobilization

  17. Orbital exenteration: The 10-year Massachusetts Eye and Ear Infirmary experience.

    Science.gov (United States)

    Nagendran, Sonali T; Lee, N Grace; Fay, Aaron; Lefebvre, Daniel R; Sutula, Francis C; Freitag, Suzanne K

    2016-08-01

    The authors report their experience with orbital exenteration surgery at one academic institution over a 10-year period and review the literature. This retrospective cohort study monitored outcomes of all patients who underwent orbital exenteration surgery at Massachusetts Eye and Ear Infirmary between January 2003 and January 2013. Patients with no follow-up data or survival data were excluded from the study. The main outcome measures were surgical complications, disease status of surgical margins, need for adjuvant treatment, local recurrence, metastases and survival. 23 patients with malignancy and 2 with mucormycosis met inclusion criteria for the study. Surgical procedures included non-lid sparing total exenteration (44%), lid-sparing total exenteration (32%), non-lid sparing partial exenteration (8%) and lid-sparing partial exenteration (16%). 44% underwent additional extra-orbital procedures. Survival rates were 72% at 1 year, 48% at 3 years, and 37% at 5 years. Of patients with malignancies, 48% had clear margins after exenteration. There was no statistically significant difference in survival between patients with negative surgical margins compared to positive margins (p = 0.12). Mortality was highest in patients with melanoma (85.7%) and lowest in patients with non-squamous cell lid malignancies (0%). Our study suggests that the type of disease has a much greater impact on the survival of patients undergoing exenteration surgery than the type of exenteration surgery or the disease status of surgical margins. Patients with non-squamous cell lid malignancies and localized orbital disease have the best prognosis for tumor eradication from this radical and highly disfiguring surgery.

  18. The 10-year Trend of Periprocedural Complication Following Carotid Artery Stenting; Single Center Experience

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Jeong-Ho [Keimyung University Dongsan Medical Center, Department of Neurology (Korea, Republic of); Kang, Jihoon; Yeo, Min-Ju; Kim, Beom Joon; Jang, Min Uk; Bae, Hee-Joon [Seoul National University College of Medicine, Department of Neurology, Stroke Center, Seoul National University Bundang Hospital (Korea, Republic of); Kwon, O-Ki; Hwang, Gyo Jun; Oh, Chang Wan [Seoul National University Bundang Hospital, Department of Neurosurgery (Korea, Republic of); Jung, Cheolkyu [Seoul National University Bundang Hospital, Department of Radiology (Korea, Republic of); Lee, Ji Sung [Soonchunhyang University Medical Center, Biostatistical Consulting Unit (Korea, Republic of); Han, Moon-Ku, E-mail: mkhan@snu.ac.kr [Seoul National University College of Medicine, Department of Neurology, Stroke Center, Seoul National University Bundang Hospital (Korea, Republic of)

    2015-04-15

    PurposeCarotid endarterectomy and stenting are used to treat carotid stenosis, with the volume of carotid artery procedures increasing over the past decade. We investigated the 10-year trend of periprocedural complications with an increasing procedure volume of carotid stenting at a single tertiary hospital.MethodsWe collected 416 consecutive cases (384 patients) of carotid artery stenting performed for either symptomatic (231 cases, 55.5 %) or asymptomatic (185 cases, 44.5 %) internal carotid artery stenosis at a single center. Periprocedural complication was defined as any stroke, myocardial infarction, or death. Procedure-related outcome included any dissection, hemodynamic event, or periprocedural complication.ResultsThe mean age was 68.8 years (82.8 % males; range of 20–89 years); 23.9 % were older than 75 years. Before the procedure, 99.3 and 56.0 % of patients received antiplatelet and lipid-lowering medication, respectively. The overall periprocedural complication rate was 3.6 % (1.6 and 5.2 % in the asymptomatic and symptomatic group, respectively). The composite outcome of any stroke or death was 3.4 %. Periprocedural complication and procedure-related outcome showed a decremental trend with increasing procedure volume, and this trend remained after adjusting for confounders.ConclusionsOur study suggests that carotid stenting at an experienced center might reduce the periprocedural complications. Our periprocedural complication rate of carotid artery stenting may be comparable to, or somewhat lower than, that reported in other clinical trials.

  19. Recommendations for Serogroup B Meningococcal Vaccine for Persons 10 Years and Older.

    Science.gov (United States)

    2016-09-01

    This policy statement provides recommendations for the prevention of serogroup B meningococcal disease through the use of 2 newly licensed serogroup B meningococcal vaccines: MenB-FHbp (Trumenba; Wyeth Pharmaceuticals, a subsidiary of Pfizer, Philadelphia, PA) and MenB-4C (Bexsero; Novartis Vaccines, Siena, Italy). Both vaccines are approved for use in persons 10 through 25 years of age. MenB-FHbp is licensed as a 2- or 3-dose series, and MenB-4C is licensed as a 2-dose series for all groups. Either vaccine is recommended for routine use in persons 10 years and older who are at increased risk of serogroup B meningococcal disease (category A recommendation). Persons at increased risk of meningococcal serogroup B disease include the following: (1) persons with persistent complement component diseases, including inherited or chronic deficiencies in C3, C5-C9, properdin, factor D, or factor H or persons receiving eculizumab (Soliris; Alexion Pharmaceuticals, Cheshire, CT), a monoclonal antibody that acts as a terminal complement inhibitor by binding C5 and inhibiting cleavage of C5 to C5A; (2) persons with anatomic or functional asplenia, including sickle cell disease; and (3) healthy persons at increased risk because of a serogroup B meningococcal disease outbreak. Both serogroup B meningococcal vaccines have been shown to be safe and immunogenic and are licensed by the US Food and Drug Administration for individuals between the ages of 10 and 25 years. On the basis of epidemiologic and antibody persistence data, the American Academy of Pediatrics agrees with the Advisory Committee on Immunization Practices of the Centers for Disease Control and Prevention that either vaccine may be administered to healthy adolescents and young adults 16 through 23 years of age (preferred ages are 16 through 18 years) to provide short-term protection against most strains of serogroup B meningococcal disease (category B recommendation).

  20. Microbial profile of the vitreous aspirates in culture proven exogenous endophthalmitis: A 10-year retrospective study

    Directory of Open Access Journals (Sweden)

    H Bhattacharjee

    2016-01-01

    Full Text Available Purpose: To describe the microbiological profile and clinical outcome in the eyes with culture-proven exogenous endophthalmitis. Methods: A retrospective analysis of 495 eyes diagnosed as exogenous endophthalmitis was performed over a period of 10 years. In all, aseptically collected aqueous and vitreous aspirates were cultured for bacteria and fungus using standard microbiological techniques. Gram-stain and KOH preparation of the specimens were also performed. The antibiotic susceptibility testing for bacterial isolates was performed by Kirby-Bauer disk diffusion method. The treatment was modified according to the antibiotic sensitivity profile. The final clinical ocular condition was divided into improved, stable or deteriorated. Results: Of 148 culture-proven endophthalmitis eyes, 137 (92.57% were referred from elsewhere, and 11 (7.43% belonged to our institute. Aetiologically, 76 (51.35% eyes were post-cataract surgery, 61 (41.22% were post-traumatic, 5 (3.38% eyes post-intravitreal anti-vascular endothelial growth factor injection, 5 associated with corneal diseases and 1 bleb-related endophthalmitis. In 31 (20.95% eyes, primary intravitreal antibiotics were given outside. The cultures revealed monomicrobial growth in 92.57% (n = 137 and polymicrobial growth in 7.43% (n = 11. Among the bacteria (n = 121, 81.76%, Pseudomonas species dominated overall (n = 32, 27.11% and post-operative (n = 26, 38.23% endophthalmitis group. Staphylococcus epidermidis (n = 14, 28% was prominent in post-traumatic endophthalmitis group. Ninety-two percent (n = 108 isolates of bacteria were sensitive to vancomycin. In 78 (52.7% eyes, the clinical ocular condition improved or remained stable while deteriorated in 51 (34.46%. Conclusion: A bacterial predominance was observed among causative organisms of exogenous endophthalmitis with Pseudomonas species being the most common. The appropriate surgical intervention improved or stabilised the visual acuity in nearly

  1. Haiti's progress in achieving its 10-year plan to eliminate cholera: hidden sickness cannot be cured.

    Science.gov (United States)

    Koski-Karell, Victoria; Farmer, Paul E; Isaac, Benito; Campa, Elizabeth M; Viaud, Loune; Namphy, Paul C; Ternier, Ralph; Ivers, Louise C

    2016-01-01

    Since the beginning of the cholera epidemic in Haiti 5 years ago, the prevalence of this deadly water-borne disease has fallen far below the initial rates registered during its explosive outset. However, cholera continues to cause extensive suffering and needless deaths across the country, particularly among the poor. The urgent need to eliminate transmission of cholera persists: compared to the same period in 2014, the first 4 months of 2015 saw three times the number of cholera cases. Drawing upon epidemiology, clinical work (and clinical knowledge), policy, ecology, and political economy, and informed by ethnographic data collected in a rural area of Haiti called Bocozel, this paper evaluates the progress of the nation's 10-year Plan for the Elimination of Cholera. Bocozel is a rice-producing region where most people live in extreme poverty. The irrigation network is decrepit, the land is prone to environmental shocks, fertilizer is not affordable, and the government's capacity to assist farmers is undermined by resource constraints. When peasants do have rice to sell, the price of domestically grown rice is twice that of US-imported rice. Canal water is not only used to irrigate thousands of acres of rice paddies and sustain livestock, but also to bathe, wash, and play, while water from wells, hand pumps, and the river is used for drinking, cooking, and bathing. Only one out of the three government-sponsored water treatment stations in the research area is still functional and utilized by those who can afford it. Latrines are scarce and often shared by up to 30 people; open defecation remains common. Structural vulnerabilities cut across all sectors - not just water, sanitation, health care, and education, but agriculture, environment, (global and local) commerce, transportation, and governance as well. These are among the hidden sicknesses that impede Haiti and its partners' capacity to eliminate cholera.

  2. Importance of mental performance in parental choice of food for children aged 4-10 years: a study in four European countries.

    Science.gov (United States)

    Gage, Heather; Egan, Bernadette; Williams, Peter; Brands, Brigitte; Györei, Eszter; López-Robles, Juan-Carlos; Campoy, Cristina; Decsi, Tamas; Koletzko, Berthold; Raats, Monique

    2017-04-01

    Typically, attention focuses on how nutrition affects physical health. The present study investigated the importance that parents attach to the impact of diet on mental performance when choosing food for their child. Questionnaire. Four European countries. Parents of children aged 4-10 years (n 1574): England (n 397), Germany (n 389), Hungary (n 398) and Spain (n 390). Most parents (80-85 %) considered the effect of food on four elements of mental performance (child's ability to learn, attention, behaviour, mood) to be moderately, very, extremely (v. slightly, not at all) important in food choices; over 90 % considered healthiness of food and making food appealing to their child important; 79·8 % cost; 76·8 % convenience. Belief that food affects mental performance was 57·4 % (ability to learn), 60·5 % (attention); less than 40 % of parents agreed they were aware which foods had an effect. Parents with lower general interest in healthy eating were less likely to consider the effect of food on mental performance elements as important. Respondents from Germany were more likely to rate mental performance as important (except behaviour); those in Hungary less likely. The most important influence on parents' decisions about feeding their child was their own experience, except Spain, where family/friends/health professionals were more important. Nutrition affects brain development and cognitive functioning. Low prioritisation of the effect of food on mental performance indicates potential for educating parents.

  3. Nutritional Support

    Science.gov (United States)

    Nutritional support is therapy for people who cannot get enough nourishment by eating or drinking. You may ... absorb nutrients through your digestive system You receive nutritional support through a needle or catheter placed in ...

  4. Nutritional supplements

    DEFF Research Database (Denmark)

    Petersen, Gry Bjerg; Andersen, Jens Rikardt

    2015-01-01

    Background: Several studies have indicated that cancer patients have significantly altered taste sensitivity without specifying the preferences. One of the related problems is low compliance to nutritional therapy with oral nutritional supplements (ONS) in patients suffering severe weight loss...

  5. Marked reduction of anemia during pregnancy over a 10-year period in Montserrat.

    Science.gov (United States)

    Simmons, W K; Simeon, D T; Bramble, D; Buffonge, C; Gallagher, P

    1996-03-01

    Anemia during pregnancy is associated with adverse outcomes including maternal and perinatal mortality. However, health education and other public health strategies seeking to reduce its prevalence have usually met with only limited success. The study reported here surveyed anemia of pregnancy on the island of Montserrat in 1980, 1985, and 1990. This involved examination of clinic and hospital records for over 90% of all women giving birth on Montserrat in 1980 and 1985, as well as 80% of those giving birth in 1990. This examination showed a dramatic reduction in the prevalence of anemia at the time of the first prenatal visit (a drop from 82% of the study women in 1980 to 23% in 1985 and 19% in 1990) and also a marked drop at three days postpartum (from 91% in 1980 to 41% in 1985 and 39% in 1990). Logistic regression analyses indicated that after controlling for three possible confounding factors (maternal age, parity, and weeks of gestation at first prenatal visit) the difference between the risk of developing anemia during pregnancy in 1980 as compared to 1985 or 1990 was still highly significant. The reasons for the observed drop in anemia's prevalence during the survey period are not entirely clear, partly because of the retrospective nature of the study. However, better nutrition resulting from improvement in the standard of living on Montserrat during the survey period could have been important, as could changes in health education and food supplementation activities.

  6. Development of a 10-year-old paediatric thorax finite element model validated against cardiopulmonary resuscitation data.

    Science.gov (United States)

    Jiang, Binhui; Cao, Libo; Mao, Haojie; Wagner, Christina; Marek, Stan; Yang, King H

    2014-01-01

    Thoracic injury in the paediatric population is a relatively common cause of severe injury and has an accompanying high mortality rate. However, no anatomically accurate, complex paediatric chest finite element (FE) component model is available for a 10-year old in the published literature. In this study, a 10-year-old thorax FE model was developed based on internal and external geometries segmented from medical images. The model was then validated against published data measured during cardiopulmonary resuscitation performed on paediatric subjects.

  7. Distribution of Estimated 10-Year Risk of Recurrent Vascular Events and Residual Risk in a Secondary Prevention Population.

    Science.gov (United States)

    Kaasenbrood, Lotte; Boekholdt, S Matthijs; van der Graaf, Yolanda; Ray, Kausik K; Peters, Ron J G; Kastelein, John J P; Amarenco, Pierre; LaRosa, John C; Cramer, Maarten J M; Westerink, Jan; Kappelle, L Jaap; de Borst, Gert J; Visseren, Frank L J

    2016-11-08

    Among patients with clinically manifest vascular disease, the risk of recurrent vascular events is likely to vary. We assessed the distribution of estimated 10-year risk of recurrent vascular events in a secondary prevention population. We also estimated the potential risk reduction and residual risk that can be achieved if patients reach guideline-recommended risk factor targets. The SMART score (Second Manifestations of Arterial Disease) for 10-year risk of myocardial infarction, stroke, or vascular death was applied to 6904 patients with vascular disease. The risk score was externally validated in 18 436 patients with various manifestations of vascular disease from the TNT (Treating to New Targets), IDEAL (Incremental Decrease in End Points Through Aggressive Lipid Lowering), SPARCL (Stroke Prevention by Aggressive Reduction in Cholesterol Levels), and CAPRIE (Clopidogrel Versus Aspirin in Patients at Risk of Ischemic Events) trials. The residual risk at guideline-recommended targets was estimated by applying relative risk reductions from meta-analyses to the estimated risk for targets for systolic blood pressure, low-density lipoprotein cholesterol, smoking, physical activity, and use of antithrombotic agents. The external performance of the SMART risk score was reasonable, apart from overestimation of risk in patients with 10-year risk >40%. In patients with various manifestations of vascular disease, median 10-year risk of a recurrent major vascular event was 17% (interquartile range, 11%-28%), varying from 30% in 22% of the patients. If risk factors were at guideline-recommended targets, the residual 10-year risk would be 30% in 9% of the patients (median, 11%; interquartile range, 7%-17%). Among patients with vascular disease, there is very substantial variation in estimated 10-year risk of recurrent vascular events. If all modifiable risk factors were at guideline-recommended targets, half of the patients would have a 10-year risk 20% and even >30% 10

  8. Advantages of enteral nutrition over parenteral nutrition

    OpenAIRE

    Seres, David S.; Valcarcel, Monika; Guillaume, Alexandra

    2013-01-01

    It is a strong and commonly held belief among nutrition clinicians that enteral nutrition is preferable to parenteral nutrition. We provide a narrative review of more recent studies and technical reviews comparing enteral nutrition with parenteral nutrition. Despite significant weaknesses in the existing data, current literature continues to support the use of enteral nutrition in patients requiring nutrition support, over parenteral nutrition.

  9. Pediatric septic arthritis: a 10- year epidemiologic study in Imam Khomeini Hospital Complex

    Directory of Open Access Journals (Sweden)

    Zamani A

    2010-01-01

    Full Text Available "n Normal 0 false false false EN-US X-NONE AR-SA MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:Arial; mso-bidi-theme-font:minor-bidi;} Background: Septic Arthritis is an acute infection of intra-arthicular space. Delay in diagnosis and in appropriate treatment may lead to prolongation of treatment duration and poor outcome. We decided to evaluate clinical aspects of this disease in our department pediatric department, Imam Khomeini Hospital complex, Tehran, Iran during a 10 years period."n"nMethods: In a retrospective cross-sectional study, 60 patients with age from 1 month to 14 year-old during 1996-2005 were evaluated. The demographics characteristics, clinical observations (signs & symptoms and paraclinic values were gathered from medical records and analyzed with statistical tests. "n"nResults: Pain and Swelling was seen in all, joint limited motion in 80% (50 cases claudicating in 64% (38 cases, fever in 80% (48 cases, monoarticular disease in 80% (48 cases and polyarticular one in 20% (12 cases of them. Hip was most Common involved joint 62% (37 cases, elevated ESR was seen in all patients. CRP was positive in 85% (51 cases. Leuckocytosis was found in 65/8% (17 cases of cases. In infectious cases, Staphylococcus aurous was responsible organism in 65.6% (16 cases, klebsiella in 12.4% (3 cases, Streptococcus pneumonia in 12.3% (3 cases, group b

  10. The International Space Station and the Space Debris Environment: 10 Years On

    Science.gov (United States)

    Johnson, Nicholas; Klinkrad, Heiner

    2009-01-01

    For just over a decade the International Space Station (ISS), the most heavily protected vehicle in Earth orbit, has weathered the space debris environment well. Numerous hypervelocity impact features on the surface of ISS caused by small orbital debris and meteoroids have been observed. In addition to typical impacts seen on the large solar arrays, craters have been discovered on windows, hand rails, thermal blankets, radiators, and even a visiting logistics module. None of these impacts have resulted in any degradation of the operation or mission of the ISS. Validating the rate of small particle impacts on the ISS as predicted by space debris environment models is extremely complex. First, the ISS has been an evolving structure, from its original 20 metric tons to nearly 300 metric tons (excluding logistics vehicles) ten years later. Hence, the anticipated space debris impact rate has grown with the increasing size of ISS. Secondly, a comprehensive visual or photographic examination of the complete exterior of ISS has never been accomplished. In fact, most impact features have been discovered serendipitously. Further complications include the estimation of the size of an impacting particle without knowing its mass, velocity, and angle of impact and the effect of shadowing by some ISS components. Inadvertently and deliberately, the ISS has also been the source of space debris. The U.S. Space Surveillance Network officially cataloged 65 debris from ISS from November 1998 to November 2008: from lost cameras, sockets, and tool bags to intentionally discarded equipment and an old space suit. Fortunately, the majority of these objects fall back to Earth quickly with an average orbital lifetime of less than two months and a maximum orbital lifetime of a little more than 15 months. The cumulative total number of debris object-years is almost exactly 10, the equivalent of one piece of debris remaining in orbit for 10 years. An unknown number of debris too small to be

  11. Electro interstitial scan system: assessment of 10 years of research and development

    Directory of Open Access Journals (Sweden)

    Maarek A

    2012-03-01

    children; and (4 estimation of the morphology of the interstitial fluid (selective serotonin reuptake inhibitor treatment response.Conclusion: After 10 years of development, the analysis of current scientific knowledge and results of clinical investigations have allowed a better understanding of EIS electrical measurements.Keywords: EIS, electro interstitial scan, electrochemical redox reactions, postsympathetic cholinergic electrical stimulation, ADHD, SSRI treatment responses, prostate cancer, diabetes

  12. Mucosal inflammation and incidence of crestal bone loss among implant patients: a 10-year study.

    Science.gov (United States)

    Cecchinato, Denis; Parpaiola, Andrea; Lindhe, Jan

    2014-07-01

    The objective of this prospective study was to determine the prevalence and incidence of marginal bone loss and, in addition, peri-implantitis in subjects and implant sites after 10 years in function. One hundred and thirty-three subjects with a total of 407 implants that had been in function for about 5 years attended a follow-up visit in 2007 (visit 2; V2). 100 of the 133 subjects returned for a new clinical and radiographic examination in 2012 (visit 3; V3). The clinical examination included assessment of "bleeding on probing" (BoP+) and "probing pocket depth." Subjects with implant sites that in the radiograph exhibited crater-shaped marginal bone loss of >0.5 mm were identified as losers. During the interval between V2 and V3 (about 5 years), 13 implants in 7 subjects exhibited progressive bone loss and were removed. The overall amount of crestal bone loss that had occurred at the remaining implants between visit 1 (V1; ≥1 year of loading) and V3 (10 years) was small (0.36 ± 1.4 mm). The bone-level reduction was twice as great between V2 and V3 as between V1 and V2. Forty subjects and 75 (26%) implant sites exhibited marginal bone loss of >0.5 mm between V1 and V3. In the interval between V2 and V3, 37 new implant sites lost significant amounts of bone. During the entire 10-year period (V1-V3), 12% of patients and 5% of implants displayed signs of peri-implantitis (bone loss >0.5 mm, BoP+, PPD ≥6 mm), while in the V2-V3 interval, the corresponding numbers were 10% (patients) and 4% (implant sites). Sites with marginal bone loss of ≥1 mm were not common among implant patients. Peri-implantitis occurred in about 10% of patients and 4% of implant sites. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  13. Haiti's progress in achieving its 10-year plan to eliminate cholera: hidden sickness cannot be cured

    Directory of Open Access Journals (Sweden)

    Koski-Karell V

    2016-05-01

    Full Text Available Victoria Koski-Karell,1,2 Paul E Farmer,2–4 Benito Isaac,5 Elizabeth M Campa,5 Loune Viaud,5 Paul C Namphy,6 Ralph Ternier,5 Louise C Ivers2–4 1Department of Anthropology, University of Michigan, and University of Michigan Medical School, Ann Arbor, MI, 2Partners In Health, 3Department of Global Health and Social Medicine, Harvard Medical School, 4Department of Medicine, Division of Global Health Equity, Brigham and Women's Hospital, Boston, MA, USA; 5Zanmi Lasante, Cange, 6Direction Nationale de l'Eau Potable et de l'Assainissement, Port-au-Prince, Haiti Abstract: Since the beginning of the cholera epidemic in Haiti 5 years ago, the prevalence of this deadly water-borne disease has fallen far below the initial rates registered during its explosive outset. However, cholera continues to cause extensive suffering and needless deaths across the country, particularly among the poor. The urgent need to eliminate transmission of cholera persists: compared to the same period in 2014, the first 4 months of 2015 saw three times the number of cholera cases. Drawing upon epidemiology, clinical work (and clinical knowledge, policy, ecology, and political economy, and informed by ethnographic data collected in a rural area of Haiti called Bocozel, this paper evaluates the progress of the nation's 10-year Plan for the Elimination of Cholera. Bocozel is a rice-producing region where most people live in extreme poverty. The irrigation network is decrepit, the land is prone to environmental shocks, fertilizer is not affordable, and the government's capacity to assist farmers is undermined by resource constraints. When peasants do have rice to sell, the price of domestically grown rice is twice that of US-imported rice. Canal water is not only used to irrigate thousands of acres of rice paddies and sustain livestock, but also to bathe, wash, and play, while water from wells, hand pumps, and the river is used for drinking, cooking, and bathing. Only one out of

  14. [Tumors of the adipose tissue during 10 years of diagnostic activities (1979-1988)].

    Science.gov (United States)

    Grandi, E; Trisolini, M P

    1990-01-01

    Adipose tissue tumors in ten years of diagnostic activity (1979-1988). We have reconsidered our material on tumors of adipose tissue, which were observed for 10 years, from 1979 to 1988, at Istituto di Anatomia Patologica dell'Università degli Studi - Arcispedale S. Anna di Ferrara. The whole collection consists of 772 tumors, 742 lipomas and 30 liposarcomas. We have intended to examine the development of our diagnostic experience through time and compare our data with those of literature. Simple lipomas and fibrolipomas are the most common histological types (78.8%), followed by angiolipomas (3.6%) and intramuscular lipomas (2.5%). The other types have a lower percentage. In every cases the morphologic and clinicopathologic features are shown, as well as compared with those of literature, and discordances that may result are interpreted. We are firmly convinced that routine diagnosis is not always compatible with rigid classifications and that it is not easy to use morphologic criteria which vary in quality and quantity. We have consequently aimed at reducing any possible distortion in diagnosis due to subjectivity, by sticking rigorously to consolidated morphology. Although our findings mostly agree with those of literature, some discordances still exist; the most significant of them regard age incidence. Among spindle cell lipomas there are two cases diagnosed in early childhood; the number of angiolipomas as well seems to be very high in this period of life. Particularly important from the clinical point of view has been the decision of diagnosing a thigh tumor as lipoblastoma in an eighteen-year-old boy. Other discordances seem to us less significant, as, for example, the absence of intramuscular lipomas in the thigh, which is to be considered, in our opinion, a chance event that we could not explain otherwise. Liposarcomas represent the 4% of the cases. Only one cases has been diagnosed in a patient less than 40 years old. The location sites agree with those

  15. Lessons Learned from 10 Years of Delivering Quality Microwave Data to Scientists

    Science.gov (United States)

    Smith, D. K.; Wentz, F. J.; Hilburn, K. A.; Gentemann, C. L.

    2009-12-01

    DISCOVER (Distributed Information Services: Climate/Ocean Products and Visualization for Earth Research) is a NASA MEaSUREs funded project that delivers ocean surface wind, water vapor, cloud, sea surface temperature and rain products to the scientific community. We have delivered these data to users via the Internet for over 10 years thanks to successive funding (Pathfinder, ESIP, REASoN and now MEaSUREs). Since we are a group of scientists who use the data ourselves in research, our approach to providing DISCOVER data to the user community is based on what we would want; that is, we provide simple file formats that are quick to download and easy to transfer between computer systems, with read routines and files to check whether the data are correct after transfer, and helpful, quick and accurate user support. Web and FTP user metrics collected since 1998 show a continual increase in activity and file downloads. Most importantly, the DISCOVER data are now essential building blocks to other value-added products created by scientists for the research community, such as the CCMP winds (another NASA MEaSUREs funded project). An extensive list of publications presenting results obtained through use of the DISCOVER data demonstrates the demand for and long-term use of the DISCOVER ocean data products by scientists. Our products are generated after extensive intercalibration, algorithm refinement, quality control checks, geolocation and satellite attitude adjustments, along-scan bias corrections, hot load or antenna emissivity corrections, sun glitter and RFI removal and independent validation. In this talk, we will summarize our methods and tools used in producing the various DISCOVER data products, describe the means by which we distribute the data to users and support them in their research, list the types of value-added products available, and present some of the ways in which the data are being used to answer important scientific and climate questions. In addition

  16. ECTOPIC CUSHING SYNDROME: A 10-YEAR EXPERIENCE FROM A TERTIARY CARE CENTER IN SOUTHERN INDIA.

    Science.gov (United States)

    Sathyakumar, Samantha; Paul, Thomas Vizhalil; Asha, Hesargatta Shyamsunder; Gnanamuthu, Birla Roy; Paul, M J; Abraham, Deepak Thomas; Rajaratnam, Simon; Thomas, Nihal

    2017-08-01

    Ectopic adrenocorticotropic hormone (ACTH) secretion is a less common cause of Cushing syndrome and is seen in 5 to 10% of cases with endogenous hypercortisolemia. We hereby describe our experience of patients with ectopic ACTH syndrome, who have been managed over the past 10 years at a tertiary care center in Southern India. The inpatient and outpatient records of patients from 2006 to 2015 were retrospectively reviewed. The clinical features, clinical history, biochemical values, imaging features, including radiologic findings and positron emission tomography scans, management, details of follow-up, and outcomes, were documented. We compared the biochemical findings in these patients with 20 consecutive patients with Cushing disease (Cushing syndrome of pituitary origin). A total of 21 patients were studied. The median age at presentation was 34 years (range, 19 to 55 years). Seven patients had thymic carcinoid, 7 had bronchial carcinoid, 3 had lung malignancies, 2 had medullary carcinoma thyroid, 1 patient had a pancreatic neuroendocrine tumor, and 1 patient had an occult source of ACTH. The most common clinical features at presentation were muscle weakness (95%), hyperpigmentation (90%), facial puffiness (76%), easy bruising (61%), edema (57%), and striae (52%). Extensive acne was seen in a large number of patients (43%). Only 3 patients (14%) had central obesity. The median 8 am cortisol was 55.5 μg/dL (range, 3.8 to 131 μg/dL), median 8 am ACTH was 207 pg/mL (range, 31.1 to 703 pg/mL), and the median 24-hour urinary free cortisol was 2,484 μg (range, 248 to 25,438 μg). Basal cortisol and ACTH, as well as midnight cortisol and ACTH level, were markedly higher in patients with ectopic Cushing syndrome as compared to patients with Cushing disease. Twelve of 21 patients had developed life-threatening infections by follow-up. Nine patients had undergone surgical intervention to address the primary tumor. However, only 1 patient exhibited a complete cure on

  17. AMIE SMART-1: review of results and legacy 10 years after launch

    Science.gov (United States)

    Josset, Jean-Luc; Souchon, Audrey; Josset, Marie; Foing, Bernard

    2014-05-01

    The Advanced Moon micro-Imager Experiment (AMIE) camera was launched in September 2003 onboard the ESA SMART-1 spacecraft. We review the technical characteristics, scientific objectives and results of the instrument, 10 years after its launch. The AMIE camera is an ultra-compact imaging system that includes a tele-objective with a 5.3° x 5.3° field of view and an imaging sensor of 1024 x 1024 pixels. It is dedicated to spectral imaging with three spectral filters (750, 915 and 960 nm filters), photometric measurements (filter free CCD area), and Laser-link experiment (laser filter at 847 nm). The AMIE camera was designed to acquire high-resolution images of the lunar surface, in white light and for specific spectral bands, under a number of different viewing conditions and geometries. Specifically, its main scientific objectives included: (i) imaging of high latitude regions in the southern hemisphere, in particular the South Pole Aitken basin and the permanently shadowed regions close to the South Pole; (ii) determination of the photometric properties of the lunar surface from observations at different phase angles (physical properties of the regolith); (iii) multi-band imaging for constraining the chemical and mineral composition of the surface; (iv) detection and characterisation of lunar non-mare volcanic units; (v) study of lithological variations from impact craters and implications for crustal heterogeneity. The study of AMIE images enhanced the knowledge of the lunar surface, in particular regarding photometric modelling and surface physical properties of localized lunar areas and geological units. References: http://scholar.google.nl/scholar?q=smart-1+amie We acknowledge ESA, member states, industry and institutes for their contribution, and the members of the AMIE Team: J.-L. Josset, P. Plancke, Y. Langevin, P. Cerroni, M. C. De Sanctis, P. Pinet, S. Chevrel, S. Beauvivre, B.A. Hofmann, M. Josset, D. Koschny, M. Almeida, K. Muinonen, J. Piironen, M. A

  18. Invasive mould sinusitis in patients with haematological malignancies: a 10 year single-centre study.

    Science.gov (United States)

    Davoudi, S; Kumar, V A; Jiang, Y; Kupferman, M; Kontoyiannis, D P

    2015-10-01

    Invasive mould sinusitis (IMS) is a severe infection in patients with haematological malignancies. Because of a paucity of contemporaneous data about IMS, we sought to evaluate clinical aspects and outcome of IMS in these patients. The records of adult haematological malignancy patients with proven or probable IMS over a 10 year period were reviewed retrospectively. We identified 44 patients with IMS. Mucorales were isolated in 13 (35.1%) patients and Fusarium and Aspergillus were isolated in 9 (24.3%) patients each. Patients with IMS owing to Mucorales were more likely to have a history of diabetes mellitus (P = 0.003) and high-dose corticosteroid use (P = 0.03). Thirty-five (80%) patients received antifungal combinations and 36 (82%) underwent surgical debridement. The 12 week IMS-attributable mortality was 36.4% (16 patients). A relapsed and/or refractory haematological malignancy was an independent risk factor for 6 week IMS-attributable (P = 0.038), 12 week all-cause (P = 0.005) and 12 week IMS-attributable (P = 0.0015) mortality. Neutrophil count <100/µL and lymphocyte count <200/µL were associated with increased 12 week IMS-attributable and 6 week all-cause mortality, respectively (P = 0.044 and 0.013). IMS due to Aspergillus was an independent risk factor for both 12 week all-cause (P = 0.011) and IMS-attributable (P = 0.026) mortality. Initial antifungal therapy with a triazole-containing regimen was associated with decreased 6 week all-cause (P = 0.032) and IMS-attributable (P = 0.038) mortality. Surgery was not an independent factor for improved outcome. Despite combined medical and surgical therapy, IMS had high mortality. Mortality risk factors were relapsed and/or refractory malignancy, cytopenia and Aspergillus infection in this study. © The Author 2015. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  19. Scientific literature addressing detection of monosialoganglioside A 10-year bibliometric analysis

    Institute of Scientific and Technical Information of China (English)

    Yanli Xu; Miaojing Li; Zhijun Liu; Aiping Xi; Chaoxian Zhao; Jianzhong Zhang

    2012-01-01

    first with 30 articles, followed by University of Medicine and Dentistry of New Jersey (28 articles), Cornell University (24 articles) and Johns Hopkins University (24 articles). In 442 articles published by Japanese, Nagoya University ranked the first with 40 articles, followed by Kinki University (36 articles), and Dokkyo University (31 articles). Though the total number of publications by Japanese is smaller than Americans, the top three institutions published more publications than American institutions. There is a markedly increase in the number of publications on the subject detection of monosialoganglioside in 2004, which the peak in the past 10 years. The valley bottom of the subject appeared in 2005. In total, the research is increased with time prolonged. Journal of Neurochemistry, Journal of Biological Chemistry and Journal of Neuroimmunology were core subject journals in monosialoganglioside studies. CONCLUSION: This study highlights the topics in detection of monosialoganglioside research that are being published around the world.

  20. Normative voice range profiles in vocally trained and untrained children aged between 7 and 10 years.

    Science.gov (United States)

    Schneider, Berit; Zumtobel, Michaela; Prettenhofer, Walter; Aichstill, Birgitta; Jocher, Werner

    2010-03-01

    Only limited data on normal vocal constitution and vocal capabilities in school-aged children are available. To take better care of children's voices, it might be helpful to know voice ranges and limits of not only vocally trained but also vocally untrained children. Goal of this study was the evaluation of singing voice capabilities of vocally healthy children with different social and vocal/musical backgrounds using voice range profile measurements (VRP). VRP percentiles that reflect constitutional aspects were suggested. In this cross-sectional study, 186 children (aged between seven and 10 years), attending five schools, were included. VRP measurements were performed under field conditions. Interviews and questionnaires regarding vocal strain and vocal training were applied; the answers were used for classification of singing activity and vocal training (KLASAK). All children reached a mean singing voice range of at least two octaves. By using the answers of interviews and questionnaires, the children could be classified according to vocal strain and vocal training. The groups showed no significant differences regarding VRP measurements. In the following step, percentiles were calculated. Twenty-five percent of all children (P25) reached a minimum voice range of almost two octaves, namely, 22 semitones (ST) from 220 to 784 Hz with soft and loud singing. Half of the children (P50) had a voice range of 24 ST (2 octaves), while soft singing and a larger voice range of 26 ST while loud singing. The measurements of third quartile (P75) revealed that 25% of children have even a larger voice range than 29 dB (from 196 Hz/g to 1047 Hz/c3) and can sing at most frequencies louder than 90 dB. P90 demonstrated that 10% of the children can sing even lower or higher than the frequency range between 196 Hz/g and 1319 Hz/e3 analyzed. The voice range seems not to be constrained by social but by voice/musical background: children of vocally/musically encouraged schools had wider

  1. Dietary fat intakes in Irish adults in 2011: how much has changed in 10 years?

    Science.gov (United States)

    Li, Kaifeng; McNulty, Breige A; Tiernery, Ann M; Devlin, Niamh F C; Joyce, Triona; Leite, Joao C; Flynn, Albert; Walton, Janette; Brennan, Lorraine; Gibney, Michael J; Nugent, Anne P

    2016-05-28

    Imbalances in dietary fat intakes are linked to several chronic diseases. This study describes dietary intakes and food sources of fat and fatty acids in 1051 Irish adults (aged 18-90 years), using data from the 2011 national food consumption survey, the National Adult Nutrition Survey. It also compares current intakes for 18-64-year-olds with those reported in the last such survey in 2001, the North/South Ireland Food Consumption Survey. Dietary fat intakes were estimated using data from 4-d semi-weighed (2011) and 7-d estimated (2001) food diaries. In 2011, intakes for 18-64-year-olds were as follows: total fat, 34·1 (sd 6·1) % total energy (%TE); SFA, 13·3 (sd 3·3) %TE; MUFA, 12·5 (sd 2·6) %TE; PUFA, 6·1 (sd 2·2) %TE; and trans-fat, 0·511 (sd 0·282) %TE. Apart from MUFA, intakes decreased (P65 years had the highest intakes of SFA; however, intakes were typically higher than UK-recommended values for all groups. In contrast, intakes of long-chain n-3 fatty acids were lowest in younger age groups. Intakes of trans-fat were well within UK-recommended levels. Although there have been some improvements in the profile of intakes since 2001, imbalances persist in the quantity and quality of dietary fat consumed by Irish adults, most notably for total and SFA and for younger age groups for long-chain n-3 fatty acids.

  2. Nutrition Labeling

    DEFF Research Database (Denmark)

    Grunert, Klaus G

    2013-01-01

    because consumers will avoid products that the label shows to be nutritionally deficient, but also because food producers will try to avoid marketing products that appear, according to the label, as nutritionally problematic, for example, because of a high content of saturated fat or salt. Nutrition......Nutrition labeling refers to the provision of information on a food product’s nutritional content on the package label. It can serve both public health and commercial purposes. From a public health perspective, the aim of nutrition labeling is to provide information that can enable consumers...... to make healthier choices when choosing food products. Nutrition labeling is thus closely linked to the notion of the informed consumer, that chooses products according to their aims, on the basis of the information at their disposal. Because many consumers are assumed to be interested in making healthy...

  3. Nutrition Labeling

    DEFF Research Database (Denmark)

    Grunert, Klaus G

    2013-01-01

    because consumers will avoid products that the label shows to be nutritionally deficient, but also because food producers will try to avoid marketing products that appear, according to the label, as nutritionally problematic, for example, because of a high content of saturated fat or salt. Nutrition......Nutrition labeling refers to the provision of information on a food product’s nutritional content on the package label. It can serve both public health and commercial purposes. From a public health perspective, the aim of nutrition labeling is to provide information that can enable consumers...... to make healthier choices when choosing food products. Nutrition labeling is thus closely linked to the notion of the informed consumer, that chooses products according to their aims, on the basis of the information at their disposal. Because many consumers are assumed to be interested in making healthy...

  4. 10-year trajectories of depressive symptoms and risk of dementia: a population-based study.

    Science.gov (United States)

    Mirza, Saira Saeed; Wolters, Frank J; Swanson, Sonja A; Koudstaal, Peter J; Hofman, Albert; Tiemeier, Henning; Ikram, M Arfan

    2016-07-01

    Late-life depressive symptoms have been extensively studied for their relationship with incident dementia, but have been typically assessed at a single timepoint. Such an approach neglects the course of depression, which, given its remitting and relapsing nature, might provide further insights into the complex association of depression with dementia. We therefore repeatedly measured depressive symptoms in a population of adults over a decade to study the subsequent risk of dementia. Our study was embedded in the Rotterdam Study, a population-based study of adults aged 55 years or older in Rotterdam (Netherlands), ongoing since 1990. The cohort is monitored continuously for major events by data linkage between the study database and general practitioners. We examined a cohort of participants who were free from dementia, but had data for depressive symptoms from at least one examination round in 1993-95, 1997-99, or 2002-04. We assessed depressive symptoms with the validated Dutch version of the Center for Epidemiology Depression Scale (CES-D) and the Hospital Anxiety and Depression Scale-Depression. We used these data to identify 11-year trajectories of depressive symptoms by latent class trajectory modelling. We screened participants for dementia at each examination round and followed up participants for 10 years for incident dementia by latent trajectory from the third examination round to 2014. We calculated hazard ratios (HR) for dementia by assigned trajectory using two Cox proportional hazards models (model 1 adjusted for age and sex only, and model 2 adjusted additionally for APOEɛ4 carrier status, educational level, body-mass index, smoking, alcohol consumption, cognitive score, use of antidepressants, and prevalent disease status at baseline). We repeated the analyses censoring for incident stroke, restricting to Alzheimer's disease as an outcome, and accounting for mortality as a competing risk for dementia. From 1993-2004, we obtained data for depressive

  5. Diagnostic accuracy of frozen section in Central nervous system lesions, a 10-year study.

    Directory of Open Access Journals (Sweden)

    Maliheh KHODDAMI*

    2015-01-01

    Full Text Available How to Cite This Article: Khoddami M, Akbarzadeh A, Mordai A, Bidari Zerehpoush F, Alipour H, Samadzadeh S, Alipour B.Diagnostic Accuracy of Frozen Section of Central Nervous System Lesions: A 10-Year Study. Iran J Child Neurol. 2015 Winter;9(1:25-30. AbstractObjectiveDefinitive diagnosis of the central nervous system (CNS lesions is unknown prior to histopathological examination. To determine the method and the endpoint for surgery, intraoperative evaluation of the lesion helps the surgeon.In this study, the diagnostic accuracy and pitfalls of using frozen section (FS ofCNS lesions is determined.Materials & MethodsIn this retrospective study, we analyzed the results of FS and permanent diagnoses of all CNS lesions by reviewing reports from 3 general hospitals between March 2001 and March 2011.Results273 cases were reviewed and patients with an age range from 3 to 77 years of age were considered. 166 (60.4% had complete concordance between FS and permanent section diagnosis, 83 (30.2% had partial concordance, and 24 cases (9.5% were discordant. Considering the concordant and partially concordant cases, the accuracy rate was 99.5%, sensitivity was 91.4%, specificity was 99.7%, and positive and negative predictive values were 88.4% and 99.8%, respectively.ConclusionOur results show high sensitivity and specificity of FS diagnosis in the evaluation of CNS lesions. A Kappa agreement score of 0.88 shows high concordance for FS results with permanent section. Pathologist’s misinterpretation, small biopsy samples (not representative of the entire tumor, suboptimal slides, and inadequate information about tumor location and radiologic findings appear to be the major causes for these discrepancies indicated from our study. ReferencesTaxy JB, Anthony G. Biopsy interpretation: the frozen section. 1st ed. China: Lippincott Williams & Wilkins; 2010. P.301-3.Somerset HL, Kleinschmidt-DeMasters BK. Approach to the intraoperative consultation for

  6. ESA SMART-1 mission: review of results and legacy 10 years after launch

    Science.gov (United States)

    Foing, Bernard

    2014-05-01

    We review ESA's SMART-1 highlights and legacy 10 years after launch. The SMART-1 mission to the Moon achieved record firsts such as: 1) first Small Mission for Advanced Research and Technology; with spacecraft built and integrated in 2.5 years and launched 3.5 years after mission approval; 2) first mission leaving the Earth orbit using solar power alone with demonstration for future deep space missions such as BepiColombo; 3) most fuel effective mission (60 litres of Xenon) and longest travel (13 month) to the Moon!; 4) first ESA mission reaching the Moon and first European views of lunar poles; 5) first European demonstration of a wide range of new technologies: Li-Ion modular battery, deep-space communications in X- and Ka-bands, and autonomous positioning for navigation; 6) first lunar demonstration of an infrared spectrometer and of a Swept Charge Detector Lunar X-ray fluorescence spectrometer ; 7) first ESA mission with opportunity for lunar science, elemental geochemistry, surface mineralogy mapping, surface geology and precursor studies for exploration; 8) first controlled impact landing on the Moon with real time observations campaign; 9) first mission supporting goals of the ILEWG/COSPAR International Lunar Exploration Working Group in technical and scientific exchange, international collaboration, public and youth engagement; 10) first mission preparing the ground for ESA collaboration in Chandrayaan-1, Chang'E1-2-3 and near-future landers, sample return and human lunar missions. The SMART-1 technology legacy is applicable to geostationary satellites and deep space missions using solar electric propulsion. The SMART-1 archive observations have been used to support scientific research and prepare subsequent lunar missions and exploration. Most recent SMART-1 results are relevant to topics on: 1) the study of properties of the lunar dust, 2) impact craters and ejecta, 3) the study of illumination, 4) observations and science from the Moon, 5) support to

  7. Postoperative epidural analgesia for patients undergoing pectus excavatum corrective surgery: a 10-year retrospective analysis

    Directory of Open Access Journals (Sweden)

    Siddiqui A

    2016-05-01

    Full Text Available Asad Siddiqui,1 Andrew Tse,2 James E Paul,3 Peter Fitzgerald,4 Bernice Teh,51Department of Anesthesia, University of Toronto, Toronto, 2Department of Anesthesia, University of Ottawa, Ottawa, 3Department of Anesthesia, 4Department of Surgery, McMaster University, Hamilton, Ontario, Canada; 5Canterbury Anesthetic Services, Victoria, Australia Introduction: Managing postoperative pain in patients undergoing minimally invasive pectus excavatum repair (Nuss procedure is challenging but essential in facilitating ambulation and minimizing the length of stay. Although multiple epidural regimens with varying opioids are presently used for pain management, there is currently no clinical consensus regarding which epidural regimen provides the best analgesia outcomes with the fewest side effects. This 10-year retrospective cohort study was performed to compare the quality of analgesia and the incidence of side effects associated with the three most common epidural regimens used at a tertiary care children's hospital, in patients undergoing the Nuss procedure. Methods: Seventy-two pediatric patients were identified as having been treated with one of three epidural regimens for postoperative pain management following the Nuss procedure: Group A (n=12 received 0.125% bupivacaine and 5 µg/mL fentanyl, Group B (n=21 received 0.125% bupivacaine and 10 µg/mL hydromorphone, and Group C (n=39 received 0.1% ropivacaine and 20 µg/mL hydromorphone. Our primary outcome was maximal daily pain scores (numerical rating scale 0–10, with an analytical focus on postoperative day 1 scores. The primary outcome was analyzed using linear regression. The secondary outcomes included the length of stay, side-effect profiles as reflected by the number of treatments for nausea and pruritus, pain scores according to epidural site insertion, occurrence of breakthrough pain, and presence of severe pain throughout their hospital stay. Secondary outcomes were analyzed using linear or

  8. Postoperative epidural analgesia for patients undergoing pectus excavatum corrective surgery: a 10-year retrospective analysis

    Science.gov (United States)

    Siddiqui, Asad; Tse, Andrew; Paul, James E; Fitzgerald, Peter; Teh, Bernice

    2016-01-01

    Introduction Managing postoperative pain in patients undergoing minimally invasive pectus excavatum repair (Nuss procedure) is challenging but essential in facilitating ambulation and minimizing the length of stay. Although multiple epidural regimens with varying opioids are presently used for pain management, there is currently no clinical consensus regarding which epidural regimen provides the best analgesia outcomes with the fewest side effects. This 10-year retrospective cohort study was performed to compare the quality of analgesia and the incidence of side effects associated with the three most common epidural regimens used at a tertiary care children’s hospital, in patients undergoing the Nuss procedure. Methods Seventy-two pediatric patients were identified as having been treated with one of three epidural regimens for postoperative pain management following the Nuss procedure: Group A (n=12) received 0.125% bupivacaine and 5 µg/mL fentanyl, Group B (n=21) received 0.125% bupivacaine and 10 µg/mL hydromorphone, and Group C (n=39) received 0.1% ropivacaine and 20 µg/mL hydromorphone. Our primary outcome was maximal daily pain scores (numerical rating scale 0–10), with an analytical focus on postoperative day 1 scores. The primary outcome was analyzed using linear regression. The secondary outcomes included the length of stay, side-effect profiles as reflected by the number of treatments for nausea and pruritus, pain scores according to epidural site insertion, occurrence of breakthrough pain, and presence of severe pain throughout their hospital stay. Secondary outcomes were analyzed using linear or logistic regression adjusted for pain scores at baseline. The criterion for statistical significance was set a priori at alpha =0.05. Results Group A had significantly higher day-1 pain scores (score 5.42/10) than Group B (4.52/10; P=0.030) and Group C (4.49/10; P=0.015) after adjusting for baseline pain and age. No significant difference in maximum daily

  9. Clinicopathological Characteristics of Mucinous Breast Cancer: A Retrospective Analysis of a 10-Year Study.

    Directory of Open Access Journals (Sweden)

    Lei Lei

    Full Text Available Mucinous breast carcinoma (MC is a special type of breast cancer that presents with a large amount of extracellular mucin. MC comprises approximately 4% of all invasive breast cancers. This type of tumor has a better prognosis and higher incidence in peri- and post-menopausal patients. Pathologically, there are two main subtypes of MC: pure and mixed. In this study, we describe 10 years of experience with MC at the Zhejiang Cancer Hospital in China, specifically, clinical data, histological findings and immunohistochemical features.We identified MC patients who were diagnosed as operable and completed clinical treatment from January 2001 to January 2011. The clinicopathological data included the age at diagnosis, tumor size, TNM stage, presence and number of lymph node (LN metastases, estrogen receptor (ER, progesterone receptor (PR and human epidermal growth factor receptor-2 (HER2 status and p53 expression. If the tumor was defined as mixed mucinous carcinoma (MMC, IHC was performed on a non-mucinous part, such as invasive ductal and lobular cancer. We evaluated the clinical characteristics of all MC patients using chi-square, one-way ANOVA and LSD tests. We also studied the correlations between all of the clinical parameters and LN metastasis in a binary logistic regression analysis. We used ten consecutive years of data that were collected at Zhejiang Cancer Hospital.We identified 48 cases of pure mucinous carcinoma (PMC and 77 cases of MMC. The 48 PMC cases consisted of 38 PMC-A and 10 PMC-B subtypes. The MMCs were divided into two groups, those with partial mixed mucinous breast carcinoma (pMMC, 58 cases and those with main mixed mucinous breast carcinoma (mMMC, 19 cases. pMMC was defined by tumors with less than 50% mucinous components, while mMMC was defined by tumors where the mucinous component accounted for 50% to 90% of the tumor. No significant differences in the clinicopathological characteristics were noted between the patients

  10. Gender, cohort and geographical differences in 10-year mortality in elderly people living in 12 European towns

    NARCIS (Netherlands)

    Amorim Cruz, J.A.; Haveman-Nies, A.; Schlettwein-Gsell, D.; Henauw, de S.

    2002-01-01

    BACKGROUND: In 1988/89, 2586 randomly selected elderly of both sexes born between 1913 and 1918 and living in 19 centres of 12 European countries participated in the SENECA Study on Nutrition and the Elderly in Europe. Differences in nutritional and health status as well in lifestyle factors, namely

  11. Gender, cohort and geographical differences in 10-year mortality in elderly people living in 12 European towns

    NARCIS (Netherlands)

    Amorim Cruz, J.A.; Haveman-Nies, A.; Schlettwein-Gsell, D.; Henauw, de S.

    2002-01-01

    BACKGROUND: In 1988/89, 2586 randomly selected elderly of both sexes born between 1913 and 1918 and living in 19 centres of 12 European countries participated in the SENECA Study on Nutrition and the Elderly in Europe. Differences in nutritional and health status as well in lifestyle factors, namely

  12. Smoking, antioxidant supplementation and dietary intakes among older adults with age-related macular degeneration over 10 years.

    Directory of Open Access Journals (Sweden)

    Bamini Gopinath

    Full Text Available We aimed to compare the micronutrient usage and other lifestyle behaviors over 10 years among those with and without age-related macular degeneration (AMD. 1612 participants aged 49+ years at baseline were re-examined over 10 years, west of Sydney, Australia. AMD was assessed from retinal photographs. Dietary data were collected using a semi-quantitative food frequency questionnaire. Smoking status was self-reported. 56 participants had any AMD at baseline, of these 25% quit smoking at 5 years and were still not smoking at 10-year follow-up. Among participants who had below the recommended intake of vitamins A, C or E supplements at baseline, those who did compared to those who did not develop late AMD over 10 years were more likely to report vitamins A (total, C or E supplement intake above the recommended intake at 10-year follow-up: multivariable-adjusted OR 4.21 (95% CI 1.65-10.73; OR 6.52 (95% CI 2.76-15.41; and OR 5.71 (95% CI 2.42-13.51, respectively. Participants with compared to without AMD did not appreciably increase fish, fruit and vegetable consumption and overall diet quality. Adherence to smoking and dietary recommendations was poor among older adults with AMD. However, uptake of antioxidant supplements increased significantly among those with late AMD.

  13. Long-term use of cellular phones and brain tumours: increased risk associated with use for > or =10 years.

    Science.gov (United States)

    Hardell, Lennart; Carlberg, Michael; Söderqvist, Fredrik; Mild, Kjell Hansson; Morgan, L Lloyd

    2007-09-01

    To evaluate brain tumour risk among long-term users of cellular telephones. Two cohort studies and 16 case-control studies on this topic were identified. Data were scrutinised for use of mobile phone for > or =10 years and ipsilateral exposure if presented. The cohort study was of limited value due to methodological shortcomings in the study. Of the 16 case-control studies, 11 gave results for > or =10 years' use or latency period. Most of these results were based on low numbers. An association with acoustic neuroma was found in four studies in the group with at least 10 years' use of a mobile phone. No risk was found in one study, but the tumour size was significantly larger among users. Six studies gave results for malignant brain tumours in that latency group. All gave increased odd ratios (OR), especially for ipsilateral exposure. In a meta-analysis, ipsilateral cell phone use for acoustic neuroma was OR = 2.4 (95% CI 1.1 to 5.3) and OR = 2.0, (1.2 to 3.4) for glioma using a tumour latency period of > or =10 years. Results from present studies on use of mobile phones for > or =10 years give a consistent pattern of increased risk for acoustic neuroma and glioma. The risk is highest for ipsilateral exposure.

  14. Rosetta begins its 10-year journey to the origins of the Solar System

    Science.gov (United States)

    2004-03-01

    Rosetta’s mission began at 08h17 CET (07h17 GMT) on 2 March when a European Ariane 5 launch vehicle liftered off from the Guiana Space Centre, Europe’s spaceport in Kourou, French Guiana. The launcher successfully placed its upper stage and payload into an eccentric coast orbit (200 x 4000 km). About two hours later, at 10h14 CET (09h14 GMT) the upper stage ignited its own engine to reach an escape velocity in order to leave the Earth’s gravity field and enter heliocentric orbit. The Rosetta probe was released about 18 minutes later. “After the recent success of Mars Express, Europe is now heading to deep space with another fantastic mission. We will have to be patient, as the rendezvous with the comet will not take place until ten years from now, but I think it’s worth the wait” said ESA’s Director General Jean-Jacques Dordain witnessing the launch from Kourou. ESA’s Operations Centre (ESOC) in Darmstadt, Germany, has established contact with the probe as it flies away from Earth at a relative speed of about 3.4 km/s. ESOC will be in charge of Rosetta operations and orbit determination throughout the mission. During the next eight months, the spacecraft’s onboard systems will be checked and its science payload will be commissioned. A 10-year odyssey Rosetta will be reactivated for planetary flybys, which will be used to modify its trajectory through gravity assist manoeuvres. During the trip, the probe could also observe one or more asteroids, observation of asteroids being one of the mission's secondary objectives. The first planetary encounter will be in March 2005, as Rosetta flies by the Earth for the first time. The gravity assist will boost Rosetta into an orbit that will take it to Mars two years later. During its close encounter with Mars in February 2007, Rosetta will approach to a distance of about 200 km and conduct science observations. This Martian flyby will be followed by another Earth flyby in November the same year. Both

  15. Hybrid total knee arthroplasty: a retrospective analysis of clinical and radiographic outcomes at average 10 years follow-up.

    Science.gov (United States)

    Illgen, Richard; Tueting, Jonathan; Enright, Timothy; Schreibman, Ken; McBeath, Andrew; Heiner, John

    2004-10-01

    Cemented total knee arthroplasty has demonstrated high success rates at 10-12 years. Although many cementless designs have demonstrated inferior outcomes, hybrid fixation has not been studied in detail. We retrospectively reviewed 112 hybrid total knee arthroplasties (PCA-67 and Duracon-45) after clinical and radiographic review using the SF-12 and Knee Society Scores at an average 10-year follow-up. The revision rate was 4.5%: 4 occurred in patients with metal-backed patellae and 1 in a patient with infection. No revisions were performed for aseptic loosening of the femoral component. Hybrid total knee arthroplasty with these designs provided excellent clinical and radiographic performance at 10 years comparable to cemented series. Aseptic loosening and radiographic failure rates were 0% if patients with metal-backed patellae were excluded. The durability of hybrid fixation beyond 10 years deserves further study.

  16. Treatment and violent behavior in persons with first episode psychosis during a 10-year prospective follow-up study.

    Science.gov (United States)

    Langeveld, Johannes; Bjørkly, Stål; Auestad, Bjørn; Barder, Helene; Evensen, Julie; Ten Velden Hegelstad, Wenche; Joa, Inge; Johannessen, Jan Olav; Larsen, Tor Ketil; Melle, Ingrid; Opjordsmoen, Stein; Røssberg, Jan Ivar; Rund, Bjørn Rishovd; Simonsen, Erik; Vaglum, Per; McGlashan, Thomas; Friis, Svein

    2014-07-01

    First episode psychosis (FEP) patients have an increased risk for violence and criminal activity prior to initial treatment. However, little is known about the prevalence of criminality and acts of violence many years after implementation of treatment for a first episode psychosis. To assess the prevalence of criminal and violent behaviors during a 10-year follow-up period after the debut of a first psychosis episode, and to identify early predictors and concomitant risk factors of violent behavior. A prospective design was used with comprehensive assessments of criminal behavior, drug abuse, clinical, social and treatment variables at baseline, five, and 10-year follow-up. Additionally, threatening and violent behavior was assessed at 10-year follow-up. A clinical epidemiological sample of first-episode psychosis patients (n=178) was studied. During the 10-year follow-up period, 20% of subjects had been apprehended or incarcerated. At 10-year follow-up, 15% of subjects had exposed others to threats or violence during the year before assessment. Illegal drug use at baseline and five-year follow-up, and a longer duration of psychotic symptoms were found to be predictive of violent behavior during the year preceding the 10-year follow-up. After treatment initiation, the overall prevalence of violence in psychotic patients drops gradually to rates close to those of the general population. However, persistent illicit drug abuse is a serious risk factor for violent behavior, even long after the start of treatment. Achieving remission early and reducing substance abuse may contribute to a lower long-term risk for violent behavior in FEP patients. Copyright © 2014 Elsevier B.V. All rights reserved.

  17. Pro-Adrenomedullin predicts 10-year all-cause mortality in community-dwelling patients: a prospective cohort study.

    Science.gov (United States)

    Odermatt, Jonas; Meili, Marc; Hersberger, Lara; Bolliger, Rebekka; Christ-Crain, Mirjam; Briel, Matthias; Bucher, Heiner C; Mueller, Beat; Schuetz, Philipp

    2017-07-04

    Several studies found mid-regional pro-adrenomedullin (ProADM), the prohormone of the cardiovascular protein adrenomedullin, to be strongly associated with short-term mortality, mostly in the inpatient setting. We evaluated associations of ProADM levels with 10-year mortality in community-dwelling primary care patients with respiratory tract infections. This is a post-hoc analysis using clinical and biomarker data of 134 primary care patients with respiratory tract infections. ProADM was measured on admission and after 7 days in batch-analysis. 10-year follow-up data was collected by GP, patient and relative tracing through phone interviews. We calculated Cox regression models and area under the receiver operating characteristics curves to assess associations of ProADM with 10-year all-cause mortality. During the 10-year follow-up 6% of included patients died. Median baseline ProADM blood levels (nmol/l) were significantly higher in non-survivors compared to survivors (0.5, IQR 0.4-1.3; vs. 0.2, IQR 0.1-0.5; p = 0.02) and showed a significant association with 10-year all-cause mortality in an age-adjusted cox regression model (HR: 2.5, 95%-CI: 1.0-6.1, p = 0.04). ProADM levels on day 7 showed similar results. This posthoc analysis found an association of elevated ProADM blood levels and 10-year all-cause mortality in a primary care cohort with respiratory tract infections. Due to the methodological limitations including incomplete data regarding follow-up information and biomarker measurement, this study warrants validation in future larger studies. Current Controlled Trials, SRCTN73182671.

  18. 10-year effect of Oportunidades, Mexico's conditional cash transfer programme, on child growth, cognition, language, and behaviour: a longitudinal follow-up study.

    Science.gov (United States)

    Fernald, Lia C H; Gertler, Paul J; Neufeld, Lynnette M

    2009-12-12

    Mexico's conditional cash transfer programme, Oportunidades, was started to improve the lives of poor families through interventions in health, nutrition, and education. We investigated the effect of Oportunidades on children almost 10 years after the programme began. From April, 1998, to October, 1999, low-income communities were randomly assigned to be enrolled in Oportunidades immediately (early treatment, n=320) or 18 months later (late treatment, n=186). In 2007, when 1093 children receiving early treatment and 700 late treatment in these communities were aged 8-10 years, they were assessed for outcomes including physical growth, cognitive and language development, and socioemotional development. The primary objective was to investigate outcomes associated with an additional 18 months in the programme. We used cluster-adjusted t tests and multivariate regressions to compare effects of programme participation for height-for-age, body-mass index (BMI), and cognitive language and behavioural assessment scores in early versus late treatment groups. Early enrolment reduced behavioural problems for all children in the early versus late treatment group (mean behaviour problem score -0.09 [SD 0.97] vs 0.13 [1.03]; p=0.0024), but we identified no difference between groups for mean height-for-age Z scores (-1.12 [0.96] vs -1.14 [0.97]; p=0.88), BMI-for-age Z scores (0.14 [0.99] vs 0.17 [1.06]; p=0.58), or assessment scores for language (98.8 [13.8] vs 98.4 [14.6] p=0.90) or cognition (98.8 [12.9] vs 100.2 [13.2]; p=0.26). An additional 18 months of the programme before age 3 years for children aged 8-10 years whose mothers had no education resulted in improved child growth of about 1.5 cm assessed as height-for-age [corrected] Z score (beta 0.23 [0.023-0.44] p=0.029), independently of cash received. An additional 18 months in the Oportunidades programme has independent beneficial effects other than money, especially for women with no formal education. The money itself

  19. [Community Nutrition].

    Science.gov (United States)

    Aranceta, Javier

    2004-06-01

    In the last 20 years, Public Health Nutrition focused mainly on the qualitative aspects which may influence the onset of chronic diseases, quality of life, physical and mental performance and life expectancy. This applied knowledge organised as part of preventive and health promotion programs led to the development of Community Nutrition. The aim of Community Nutrition actions is to adequate lifestyles related to food consumption patterns in order to improve the quality of life and contribute to health promotion of the population in the community where programs and services are delivered. Key functions to develop in a Community Nutrition Unit consist in the identification and assessment of nutrition problems in the community as well as the design, implementation and evaluation of intervention programs by means of appropriate strategies. These should aim at different populations groups and settings, such as work places, schools, high risk groups or the general public. Nowadays, Community Nutrition work efforts should focus on three main aspects: nutrition education in schools and in the community; food safety and food security and the development and reinforcement of food preparation skills across all age groups. Social catering services, either in schools, the work place or at the community level, need to ensure adequate nutritional supply, provide foods contributing to healthy eating practices as well as to enhance culinary traditions and social learning. Food safety and food security have become a top priority in Public Health. The concepts referes to the availability of food safe and adequate as well as in sufficient amount in order to satisfy nutrition requirements of all individuals in the community. Social changes along new scientific developments will introduce new demands in Community Nutrition work and individual dietary counselling will become a key strategy. In order to face new challenges, community nutrition pactitioners require a high quality

  20. Laryngeal preservation with induction chemotherapy for hypopharyngeal squamous cell carcinoma : 10-year results of EORTC trial 24891

    NARCIS (Netherlands)

    Lefebvre, J. -L.; Andry, G.; Chevalier, D.; Luboinski, B.; Collette, L.; Traissac, L.; de Raucourt, D.; Langendijk, J. A.

    2012-01-01

    We report the 10-year results of the EORTC trial 24891 comparing a larynx-preservation approach to immediate surgery in hypopharynx and lateral epilarynx squamous cell carcinoma. Two hundred and two patients were randomized to either the surgical approach (total laryngectomy with partial pharyngecto

  1. Effective and Legitimate? Learning from the Lessons of 10 Years of Practice with the European Arrest Warrant

    NARCIS (Netherlands)

    Marin, Luisa

    2014-01-01

    The article examines the European Arrest Warrant (EAW) and the issues which have emerged in its first 10 years of practice. After a first section explaining the choice for the principle of mutual recognition as expression of effectiveness and subsidiarity in judicial cooperation in criminal matters,

  2. Severe episodic viral wheeze in preschool children : High risk of asthma at age 5-10 years

    NARCIS (Netherlands)

    Kappelle, Lucie; Brand, Paul L. P.

    2012-01-01

    In population studies, most children with episodic viral wheeze (EVW) become symptom free by 6 years. We studied the outcome of children with severe EVW, treated and followed up in hospital. We followed up 78 children <4 years, managed by paediatricians for severe EVW, to the age of 5-10 years. We r

  3. Morbidity and mortality in the antiphospholipid syndrome during a 10-year period : A multicentre prospective study of 1000 patients

    NARCIS (Netherlands)

    Cervera, R.; Serrano, R.; Pons-Estel, G. J.; Ceberio-Hualde, L.; Shoenfeld, Y.; De Ramón, E.; Buonaiuto, V.; Jacobsen, S.; Zeher, M. M.; Tarr, T.; Tincani, A.; Taglietti, M.; Theodossiades, G.; Nomikou, E.; Galeazzi, M.; Bellisai, F.; Meroni, P. L.; Derksen, R. H W M; De Groot, P. G D; Baleva, M.; Mosca, S.; Bombardieri, M.; Houssiau, F.; Gris, J. C.; Quéré, I.; Hachulla, E.; Vasconcelos, C.; Fernández-Nebro, A.; Haro, M.; Amoura, Z.; Miyara, M.; Tektonidou, M.; Espinosa, G.; Bertolaccini, M. L.; Khamashta, M. A.

    2015-01-01

    Objectives: To assess the prevalence of the main causes of morbi-mortality in the antiphospholipid syndrome (APS) during a 10-year-follow-up period and to compare the frequency of early manifestations with those that appeared later. Methods: In 1999, we started an observational study of 1000 APS pat

  4. The Pre-Incubator: A Longitudinal Study of 10 Years of University Pre-Incubation in Wales

    Science.gov (United States)

    Voisey, Pamela; Jones, Paul; Thomas, Brychan

    2013-01-01

    This paper describes a longitudinal study of over 10 years of university pre-incubation in Wales, using case studies of incubated businesses to track their performance since 2001. Surviving "graduated" businesses were investigated and quantitative and qualitative data were gathered to profile the current status of these businesses and…

  5. Does Loss of Spasticity Matter? A 10-Year Follow-up after Selective Dorsal Rhizotomy in Cerebral Palsy

    Science.gov (United States)

    Tedroff, Kristina; Lowing, Kristina; Jacobson, Dan N. O.; Astrom, Eva

    2011-01-01

    Aim: The aim of this study was to evaluate the long-term effects of selective dorsal rhizotomy (SDR) in children with cerebral palsy (CP). Method: Nineteen children (four females, 15 males; mean age 4y 7mo, SD 1y 7mo) with bilateral spastic CP, were prospectively assessed at baseline and 18 months, 3 years, and 10 years after SDR. Assessments…

  6. Morbidity and mortality in the antiphospholipid syndrome during a 10-year period : A multicentre prospective study of 1000 patients

    NARCIS (Netherlands)

    Cervera, R.; Serrano, R.; Pons-Estel, G. J.; Ceberio-Hualde, L.; Shoenfeld, Y.; De Ramón, E.; Buonaiuto, V.; Jacobsen, S.; Zeher, M. M.; Tarr, T.; Tincani, A.; Taglietti, M.; Theodossiades, G.; Nomikou, E.; Galeazzi, M.; Bellisai, F.; Meroni, P. L.; Derksen, R. H W M; De Groot, P. G D; Baleva, M.; Mosca, S.; Bombardieri, M.; Houssiau, F.; Gris, J. C.; Quéré, I.; Hachulla, E.; Vasconcelos, C.; Fernández-Nebro, A.; Haro, M.; Amoura, Z.; Miyara, M.; Tektonidou, M.; Espinosa, G.; Bertolaccini, M. L.; Khamashta, M. A.

    2015-01-01

    Objectives: To assess the prevalence of the main causes of morbi-mortality in the antiphospholipid syndrome (APS) during a 10-year-follow-up period and to compare the frequency of early manifestations with those that appeared later. Methods: In 1999, we started an observational study of 1000 APS

  7. Ophthalmic experience over 10 years in an observational nationwide Danish cohort of Fabry patients with access to enzyme replacement

    DEFF Research Database (Denmark)

    Fledelius, Hans C.; Sandfeld, Lisbeth; Rasmussen, Åse Krogh

    2015-01-01

    PURPOSE: Enzyme replacement therapy (ERT) was offered from year 2001 to patients with Fabry disease. The ophthalmic experience was analysed, as part of a general 10-year status. METHODS: A retrospective observational series comprising 39 patients (25 females, 14 males) closely followed by the end...

  8. Personality and Demographic Characteristics of Mothers and Their Ratings of Their 3- to 10-Year-Old Children's Temperament.

    Science.gov (United States)

    Mednick, Birgitte R.; And Others

    1996-01-01

    Association between maternal ratings of child temperament and 8 maternal personality and demographic factors was examined in 3 age-stratified samples with children ranging from 3 to 10 years old. Found that mothers' anxiety was related to negative temperament ratings in all three samples, as were lower levels of maternal adaptation in analyses of…

  9. Hopelessness as a Predictor of Attempted Suicide among First Admission Patients with Psychosis: A 10-Year Cohort Study

    Science.gov (United States)

    Klonsky, E. David; Kotov, Roman; Bakst, Shelly; Rabinowitz, Jonathan; Bromet, Evelyn J.

    2012-01-01

    Little is known about the longitudinal relationship of hopelessness to attempted suicide in psychotic disorders. This study addresses this gap by assessing hopelessness and attempted suicide at multiple time-points over 10 years in a first-admission cohort with psychosis (n = 414). Approximately one in five participants attempted suicide during…

  10. Ostial stenosis of the left main coronary artery in a young woman 10 years after radiation therapy.

    Science.gov (United States)

    Orzan, F; Bellis, D; Mollo, F; Brusca, A

    1995-01-01

    A 26-year-old woman developed critical stenosis of the left main coronary artery 10 years after radiation treatment for Hodgkins disease. She was operated on but died in the immediate postoperative period. At autopsy the pathological findings were indistinguishable from those described in "typical" atherosclerotic plaques.

  11. Development of floristic diversity in 10-year-old restoration forests on a bauxite mined site in Amazonia.

    Science.gov (United States)

    J. A. Parrotta; O. H. Knowles; J.M. Wunderle Jr.

    1997-01-01

    Patterns of plant and animal diversity were studied in a 10-year-old native species reforestation area at a bauxite-mined site at porto Trombetas in western Para State, Brazil. Understorey and overstorey floristic composition and structure, understorey light conditions, forest floor development and soil properties were evaluated in a total of 38 78.5-m2

  12. Severe episodic viral wheeze in preschool children : High risk of asthma at age 5-10 years

    NARCIS (Netherlands)

    Kappelle, Lucie; Brand, Paul L. P.

    In population studies, most children with episodic viral wheeze (EVW) become symptom free by 6 years. We studied the outcome of children with severe EVW, treated and followed up in hospital. We followed up 78 children <4 years, managed by paediatricians for severe EVW, to the age of 5-10 years. We

  13. Race, socioeconomic status, and obesity in 9- to 10 year-old girls : The NHLBI Growth and Health Study

    NARCIS (Netherlands)

    Kimm, SYS; Obarzanek, E; Barton, BA; Aston, CE; Similo, SL; Morrison, JA; Sabry, ZI; Schreiber, GB; McMahon, RP

    1996-01-01

    The purpose of this investigation was to determine whether measures of socioeconomic status (SES) are inversely associated with obesity in 9- to 10-year-old black and white girls and their parents. Subjects were participants in the Growth and Health Study (NGHS) of the National Heart, Lung, and Bloo

  14. Race, socioeconomic status, and obesity in 9- to 10 year-old girls : The NHLBI Growth and Health Study

    NARCIS (Netherlands)

    Kimm, SYS; Obarzanek, E; Barton, BA; Aston, CE; Similo, SL; Morrison, JA; Sabry, ZI; Schreiber, GB; McMahon, RP

    The purpose of this investigation was to determine whether measures of socioeconomic status (SES) are inversely associated with obesity in 9- to 10-year-old black and white girls and their parents. Subjects were participants in the Growth and Health Study (NGHS) of the National Heart, Lung, and

  15. Are job and personal resources associated with work ability 10 years later? The mediating role of work engagement

    NARCIS (Netherlands)

    Airila, Auli; Hakanen, Jari J.; Schaufeli, Wilmar B.; Luukkonen, Ritva; Punakallio, Anne; Lusa, Sirpa

    2014-01-01

    Using a two-wave 10-year longitudinal design, this study examined the motivational process proposed by the Job Demands-Resources (JD-R) model. The aim was to examine whether work engagement acts as a mediator between job resources (i.e. supervisory relations, interpersonal relations and task resourc

  16. The effect of control and self-medication of chronic gout in a developing country. Outcome after 10 years

    NARCIS (Netherlands)

    Darmawan, John; Rasker, Johannes J.; Nuralim, Hendri

    2003-01-01

    Objective:: We describe a 10 year observation of the effect of control of hyperuricemia compared with self-medication alone in patients with chronic gout. Methods: We studied 299 consecutively self-referred Malayo-Polynesian men with chronic gout, mean age 35 ± 14.3 SD years. Subjects comprised 228

  17. Effective and Legitimate? Learning from the Lessons of 10 Years of Practice with the European Arrest Warrant

    NARCIS (Netherlands)

    Marin, L.

    2014-01-01

    The article examines the European Arrest Warrant (EAW) and the issues which have emerged in its first 10 years of practice. After a first section explaining the choice for the principle of mutual recognition as expression of effectiveness and subsidiarity in judicial cooperation in criminal matters,

  18. A 10-year trend of dental treatments under general anesthesia of children in Taipei Veterans General Hospital

    Directory of Open Access Journals (Sweden)

    Yung-Pan Chen

    2017-04-01

    Conclusion: Over the past 10 years, there has been an increased use of GA for pediatric dental treatments, in particular, in cases with multiple dental caries. In addition, there has also been an increasing trend towards extraction of primary teeth and the use of SSCs.

  19. Verbal memory decline is less frequent at 10 years than at 2 years after temporal lobe surgery for epilepsy.

    Science.gov (United States)

    Andersson-Roswall, Lena; Malmgren, Kristina; Engman, Elisabeth; Samuelsson, Hans

    2012-08-01

    We investigated individual short- and long-term verbal memory changes after temporal lobe resection for epilepsy. Fifty-one patients (23 operated on the speech-dominant temporal lobe, DTL and 28 on the non-dominant temporal lobe, NDTL) were tested on learning/immediate recall and delayed recall of word-list and word-pairs preoperatively, 2 years postoperatively and 10years postoperatively. Changes were defined using reliable change indices of 23 healthy controls assessed at corresponding intervals. Fewer patients had reliable declines at 10 years than at 2 years (DTL: 13-35% vs 35-44%; NDTL: 0-4% vs 7-21%). Four DTL patients (17%) had reliable declines in ≥2 tests at 10-year follow-up. More NDTL patients had improvement at 10 years than at 2 years (18-30% vs 4-22%). The only risk factor for decline both short and long term was DTL resection. In conclusion, most patients had stable verbal memory postoperatively. A few DTL patients had a lasting decline at long-term follow-up, but more patients showed partial recovery, especially in the NDTL group.

  20. Adolescent Psychological and Social Predictors of Young Adult Smoking Acquisition and Cessation: A 10-Year Longitudinal Study

    NARCIS (Netherlands)

    Otten, R.; Bricker, J.B.; Liu, J.M.; Comstock, B.A.; Peterson, A.V.

    2011-01-01

    Objective: A 10-year follow-up study to test the extent to which theory-based adolescent psychological and social factors directly predict and moderate the prediction of young adult smoking acquisition and cessation. Design: A prospective community-based sample. A total of 2,970 adolescents particip

  1. Physical fitness and body composition in 8-10-year-old Danish children are associated with sports club participation

    DEFF Research Database (Denmark)

    Larsen, Malte Nejst; Nielsen, Claus M; Ørntoft, Christina

    2017-01-01

    We investigated whether physical fitness and body composition in 8-10-year-old Danish children are associated with sports club participation. The study included 423 schoolchildren, comprising 209 girls and 214 boys, of whom 67 and 74%, respectively, were active in sports clubs. Yo-Yo Intermittent...

  2. Counseling in New Orleans 10 Years after Hurricane Katrina: A Commentary on the Aftermath, Recovery and the Future

    Science.gov (United States)

    Remley, Theodore P., Jr.

    2015-01-01

    Ten years after Hurricane Katrina, the counseling profession in New Orleans has changed. The author, along with a group of counseling and other mental health professionals who were providing services at the time of the hurricane and still working in the city 10 years later, provided their impressions of counseling in New Orleans a decade after the…

  3. Frequency of Six Early Childhood Education Approaches: A 10-Year Content Analysis of Early Childhood Education Journal

    Science.gov (United States)

    Walsh, Bridget A.; Petty, Karen

    2007-01-01

    The frequency of early childhood education approaches spanning 10 years of publications was investigated. A content analysis of publications (N = 492) from "Early Childhood Education Journal" was conducted. From a previous content analysis six approaches or search words were identified: Bank Street, Head Start, High/Scope, Montessori, Reggio…

  4. Influence of Age on Clinical Performance of Mandibular Two-Implant Overdentures : A 10-Year Prospective Comparative Study

    NARCIS (Netherlands)

    Hoeksema, Arie R.; Visser, Anita; Raghoebar, Gerry M.; Vissink, Arjan; Meijer, Henny J. A.

    2016-01-01

    Purpose: The aim of this prospective comparative study was to assess whether age has influence on peri-implant health in patients treated with mandibular two-implant overdentures during a 10-year evaluation period. Materials and Methods: A prospective study was carried out with two groups of edentul

  5. Sports Nutrition.

    Science.gov (United States)

    Missouri State Dept. of Health, Jefferson City.

    This guide deals with various aspects of sports and nutrition. Twelve chapters are included: (1) "Sports and Nutrition"; (2) "Eat to Compete"; (3) "Fit Folks Need Fit Food"; (4) "The Food Guide Pyramid"; (5) "Fat Finder's Guide"; (6) "Pre- and Post-Event Meals"; (7) "Tips for the…

  6. Nutritional epigenetics

    Science.gov (United States)

    This chapter is intended to provide a timely overview of the current state of research at the intersection of nutrition and epigenetics. I begin by describing epigenetics and molecular mechanisms of eigenetic regulation, then highlight four classes of nutritional exposures currently being investiga...

  7. [Abdominal pain syndrome and quality of life in patients with cholelithiasis after cholecystectomy during a 10-year follow-up].

    Science.gov (United States)

    Makarova, Yu V; Litvinova, N V; Osipenko, M F; Voloshina, N B

    To estimate the incidence of abdominal pain syndrome (APS) and to assess quality of life (QOL) in patients within 10 years after cholecystectomy (CE). This investigation is part of a long-term prospective follow-up study of patients after CE for cholelithiasis (CL). It enrolled 145 people: 30 (21.5%) patients with baseline asymptomatic CL and 115 (80.7%) with its clinical manifestations. The time course of changes in APS and QOL were analyzed. Over 10 years, all the patients showed a decrease in the incidence of APS from 84.1% (n=95) to 66.4% (n=75; p=0.004). In Group 1 (n=89), APS was at baseline detected in all the patients; 10 years later, its incidence declined to 67.4% (n=60; p < 0.001). Biliary pains were predominant; these had been identified significantly less frequently over the 10-year period in 47 (52.8%) patients; p<0.001). In Group 2 (n=24), pre-CE APS was generally detected in 6 (25%) patients; following 10 years, the incidence rates of pain significantly increased to 62.5% (n=15; p=0.035), among which there were predominant biliary pains (in 54.2%; p<0.001) and dyspepsia from 33.3% (n=8) up to 66.7% (n=16; p=0.039). QOL in the physical and mental health domains was found to decrease in both groups. Ten years after CE, the group with the baseline clinical manifestations of CL and poorer QOL showed a lower incidence of APS mainly due to the reduced incidence of biliary pains and the baseline asymptomatic group exhibited a rise in the incidence of APS due to the appearance of biliary pains and dyspepsia.

  8. Stronger back muscles reduce the incidence of vertebral fractures: a prospective 10 year follow-up of postmenopausal women.

    Science.gov (United States)

    Sinaki, M; Itoi, E; Wahner, H W; Wollan, P; Gelzcer, R; Mullan, B P; Collins, D A; Hodgson, S F

    2002-06-01

    The long-term protective effect of stronger back muscles on the spine was determined in 50 healthy white postmenopausal women, aged 58-75 years, 8 years after they had completed a 2 year randomized, controlled trial. Twenty-seven subjects had performed progressive, resistive back-strengthening exercises for 2 years and 23 had served as controls. Bone mineral density, spine radiographs, back extensor strength, biochemical marker values, and level of physical activity were obtained for all subjects at baseline, 2 years, and 10 years. Mean back extensor strength (BES) in the back-exercise (BE) group was 39.4 kg at baseline, 66.8 kg at 2 years (after 2 years of prescribed exercises), and 32.9 kg at 10 years (8 years after cessation of the prescribed exercises). Mean BES in the control (C) group was 36.9 kg at baseline, 49.0 kg at 2 years, and 26.9 kg at 10 years. The difference between the two groups was still statistically significant at 10 year follow-up (p = 0.001). The difference in bone mineral density, which was not significant between the two groups at baseline and 2 year follow-up, was significant at 10 year follow-up (p = 0.0004). The incidence of vertebral compression fracture was 14 fractures in 322 vertebral bodies examined (4.3%) in the C group and 6 fractures in 378 vertebral bodies examined (1.6%) in the BE group (chi-square test, p = 0.0290). The relative risk for compression fracture was 2.7 times greater in the C group than in the BE group. To our knowledge, this is the first study reported in the literature demonstrating the long-term effect of strong back muscles on the reduction of vertebral fractures in estrogen-deficient women.

  9. Sports nutrition

    Directory of Open Access Journals (Sweden)

    Tomanić Milena

    2016-01-01

    Full Text Available Due to higher energy consumption, physically active people have higher nutritional requirements. In addition to other important factors for sports, such as good health and physical predisposition, adequate nutrition is a fundamental component. Sports nutrition must be well planned and individually adapted based on physical characteristics, tendencies towards gaining or losing weight, frequency, duration and intensity of training sessions. Studies have shown that a well-balanced ratio of macro and micronutrients, with the support of supplements and adequate hydration, can significantly improve athletic performance and plays a key role in achieving better results. An optimally designed nutritional program, with realistic and achievable goals, which complements a well-planned training program, is the basis for success in sports. Only when nutritional requirements are met, deficits can be prevented and performance in sport pushed to the limit.

  10. Usage Patterns of Stop Smoking Medications in Australia, Canada, the United Kingdom, and the United States: Findings from the 2006–2008 International Tobacco Control (ITC Four Country Survey

    Directory of Open Access Journals (Sweden)

    David Hammond

    2011-01-01

    Full Text Available Varenicline is a new prescription stop smoking medication (SSM that has been available in the United States since August 1, 2006, in the United Kingdom and other European Union countries since December 5, 2006, in Canada since April 12, 2007, and in Australia since January 1, 2008. There are few population-based studies that have examined use rates of varenicline and other stop smoking medications. We report data from the ITC Four Country survey conducted with smokers in the US, UK, Canada, and Australia who reported an attempt to quit smoking in past year in the 2006 survey (n = 4,022 participants, 2007 (n = 3,790 participants, and 2008 surveys (n = 2,735 participants Respondents reported use of various stop smoking medications to quit smoking at each survey wave, along with demographic and smoker characteristics. The self-reported use of any stop smoking medication has increased significantly over the 3 year period in all 4 countries, with the sharpest increase occurring in the United States. Varenicline has become the second most used stop smoking medication, behind NRT, in all 4 countries since being introduced. Between 2006 and 2008, varenicline use rates increased from 0.4% to 21.7% in the US, 0.0% to 14.8% in Canada, 0.0% to 14.5% in Australia, and 0.0% to 4.4% in the UK. In contrast, use of NRT and bupropion remained constant in each country. Males and non-whites were significantly less likely to report using any SSM, while more educated smokers were significantly more likely to use any SSM, including varenicline. Our findings suggest that the introduction of varenicline led to an increase in the number of smokers who used evidence-based treatment during their quit attempts, rather than simply gaining market share at the expense of other medications. From a public health perspective, messages regarding increased success rates among medication users and the relative safety of stop smoking medications should be disseminated widely so as to

  11. Nutrition and Diet

    Science.gov (United States)

    ... Thai HbH:Vietnamese Relevant links Living with Thalassemia NUTRITIONNutrition and Diet ▶ Diet for the Non-transfused ... Nutrition with Connie Schroepfer, MS, RD: Dec 2016 Nutrition and Diet Nutritional deficiencies are common in thalassemia, ...

  12. Some risk factors for periodontal bone loss in 50-year-old individuals. A 10-year cohort study.

    Science.gov (United States)

    Paulander, Jörgen; Wennström, Jan L; Axelsson, Per; Lindhe, Jan

    2004-07-01

    The aim of this 10-year prospective study of 50-year-old individuals was to analyze the incidence of periodontal bone loss and potential risk factors for periodontal bone loss. The subject sample was generated from an epidemiological survey performed in 1988 of subjects living in the County of Värmland, Sweden. A randomized sample of 15% of the 50-year-old inhabitants in the county was drawn. At the 10-year follow-up in 1998, 320 (75%) of the 449 individuals examined at baseline were available for re-examination, out of which 4 had become edentulous. Full-mouth clinical and radiographic examinations and questionnaire surveys were performed in 1988 and 1998. Two hundred and ninety-five individuals (69%) had complete data for inclusion in the analysis of radiographic bone changes over 10 years. Non-parametric tests, correlations and stepwise multiple regression models were used for statistical analysis of the data. The mean alveolar bone level (ABL) in 1988 was 2.2 mm (0.05) and a further 0.4 mm (0.57) (p=0.000) was lost over the 10 years. Eight percent of the subject sample showed no loss, while 5% experienced a mean bone loss of >/=1 mm. Smoking was found to be the strongest individual risk predictor (RR=3.2; 95% CI 2.03-5.15). When including as smokers only those individuals who had continued with the habit during the entire 10-year follow-up period, the relative risk was slightly increased (3.6; 95% CI 2.32-5.57). Subjects who had quit smoking before the baseline examination did not demonstrate a significantly increased risk for disease progression (RR=1.3; 95% CI 0.57-2.96). Stepwise multiple regression analysis revealed that smoking, % approximal sites with probing pocket depth >/=4 mm, number of teeth and systemic disease were significant explanatory factors for 10-year ABL loss (R(2)=0.12). For never smokers, statistically significant predictors were number of teeth, mean ABL, % periodontally healthy approximal sites and educational level (R(2)=0.20). The

  13. Relationship Status Predicts Lower Restrictive Eating Pathology for Bisexual and Gay Men across 10-year Follow-up

    Science.gov (United States)

    Brown, Tiffany A.; Keel, Pamela K.

    2015-01-01

    Objective Cross-sectional studies support that bisexual and gay (BG) men are at increased risk for eating pathology, and romantic relationships may buffer against risk; however, no studies have examined this association longitudinally. The current study examined how romantic relationships impact the trajectory of eating pathology in BG versus heterosexual men. Method BG (n=51) and heterosexual (n=522) men completed surveys of health and eating behaviors at baseline and 10-year follow-up. Results For BG men, being single at baseline prospectively predicted an increase in Drive for Thinness scores over 10-year follow-up. Additionally, for BG men in relationships at baseline, lower relationship satisfaction predicted an increase in Drive for Thinness scores over time. Conversely, these relationship variables did not predict trajectory of eating pathology for heterosexual men. Discussion Implications for theoretical models of risk, including objectification theory and sexual minority stress theory, and prevention, including peer-led cognitive dissonance based interventions, are discussed. PMID:26172055

  14. A Randomized 10-year Prospective Follow-up of Class II Nanohybrid and Conventional Hybrid Resin Composite Restorations

    DEFF Research Database (Denmark)

    van Dijken, Jan Wv; Pallesen, Ulla

    2014-01-01

    Purpose: To evaluate the 10-year durability of a nanohybrid resin composite in Class II restorations in a randomized controlled intraindividual comparison with its conventional hybrid resin composite predecessor. Materials and Methods: Each of 52 participants received at least two Class II...... restorations that were as similar as possible. The cavities were chosen at random to be restored with a nanohybrid resin composite (Excite/Tetric EvoCeram (TEC); n = 61) and a conventional hybrid (Excite/Tetric Ceram (TC); n = 61). The restorations were evaluated with slightly modified USPHS criteria...... investigated resin composites. Conclusion: The nanohybrid and the conventional hybrid resin composite showed good clinical effectiveness in extensive Class II restorations during the 10-year study....

  15. [Association between metabolic syndrome and the 10 years mortality of cerebro-cardiovascular diseases in the senile population].

    Science.gov (United States)

    Jin, Meng-meng; Pan, Chang-Yu; Tian, Hui; Liu, Min; Su, Hai-yan

    2008-02-01

    To assess the prevalence of metabolic syndrome (MS) and its association with mortality of cerebro-cardiovascular diseases in senile population. Data were collected from 1926 people aged 60 and over, who took part in routine health examination in our hospital from 1996 to 1997. All subjects were followed up for 10 years. MS was diagnosed by using the definition recommended by Chinese Diabetic Society in 2004. Cox-proportional hazards models were used in survival analyses and to calculate the relative risk (RR) of cerebro-cardiovascular diseases mortality. The prevalence of MS was 25.03% (n = 482, Group 2) in this population. The 10 year mortality of cerebro-cardiovascular diseases was significantly higher (6.82/1000-person year vs. 2.55/1000-person year, P cerebro-cardiovascular diseases mortality was 2.52 (95% CI 1.367 - 4.661, P cerebro-cardiovascular diseases.

  16. Acute Corneal Hydrops Mimicking Infectious Keratitis as Initial Presentation of Keratoconus in a 10-Year-Old Child

    Directory of Open Access Journals (Sweden)

    Elise A. Slim

    2015-01-01

    Full Text Available Purpose. To report a case of acute hydrops in a 10-year-old child with advanced keratoconus. Case Presentation. A ten-year-old boy diagnosed as having right eye (RE infectious keratitis, not responding to antimicrobial therapy, was referred to our hospital. The diagnosis of infectious keratitis was established one month prior to his presentation following an episode of acute corneal whitening, pain, and drop in visual acuity. Topical fortified antibiotics followed by topical antiviral therapy were used with no improvement. Slit lamp examination showed significant corneal protrusion with edema surrounding a rupture in Descemet’s membrane in the RE. The diagnosis of acute corneal hydrops from advanced keratoconus was highly suspected and confirmed with corneal topography. Conclusion. Although a relatively rare disease at the age of 10 years, keratoconus can be rapidly progressive in the pediatric group. Keratoconus should always be considered in the differential diagnosis of progressive vision loss in this age group.

  17. Caries prevalence and enamel defects in 5- and 10-year-old children with cleft lip and/or palate

    DEFF Research Database (Denmark)

    Sundell, Anna Lena; Nilsson, Anna-Karin; Ullbro, Christer

    2016-01-01

    OBJECTIVE: To determine the prevalence of dental caries and enamel defects in 5- and 10-year-old Swedish children with cleft lip and/or palate (CL(P)) in comparison to non-cleft controls. MATERIALS AND METHODS: The study group consisted of 139 children with CL(P) (80 subjects aged 5 years and 59...... aged 10 years) and 313 age-matched non-cleft controls. All children were examined by one of two calibrated examiners. Caries was scored according to the International Caries Detection and Assessment System (ICDAS-II) and enamel defects as presence and frequency of hypoplasia and hypomineralization...... prevalence of enamel defects was found in CL(P) children of both age groups and anterior permanent teeth were most commonly affected. CONCLUSIONS: Preschool children with cleft lip and/or palate seem to have more caries in the primary dentition than age-matched non-cleft controls. Enamel defects were more...

  18. Relationship status predicts lower restrictive eating pathology for bisexual and gay men across 10-year follow-up.

    Science.gov (United States)

    Brown, Tiffany A; Keel, Pamela K

    2015-09-01

    Cross-sectional studies support that bisexual and gay (BG) men are at increased risk for eating pathology, and romantic relationships may buffer against risk; however, no studies have examined this association longitudinally. The current study examined how romantic relationships impact the trajectory of eating pathology in BG versus heterosexual men. BG (n = 51) and heterosexual (n = 522) men completed surveys of health and eating behaviors at baseline and 10-year follow-up. For BG men, being single at baseline prospectively predicted an increase in Drive for Thinness scores over 10-year follow-up. Additionally, for BG men in relationships at baseline, lower relationship satisfaction predicted an increase in Drive for Thinness scores over time. Conversely, these relationship variables did not predict trajectory of eating pathology for heterosexual men. Implications for theoretical models of risk, including objectification theory and sexual minority stress theory, and prevention, including peer-led cognitive dissonance based interventions, are discussed. © 2015 Wiley Periodicals, Inc.

  19. CRESESB: 10 years of activities aimed at the future; CRESESB - 10 anos de atividades visando o futuro

    Energy Technology Data Exchange (ETDEWEB)

    Galdino, Marco Antonio; Souza, Hamilton Moss de; Silva, Patricia de Castro da; Dutra, Ricardo Marques [Centro de Pesquisas de Energia Eletrica (CEPEL), Rio de Janeiro, RJ (Brazil). Dept. de Tecnologias Especiais], Emails: marcoag@cepel.br, moss@cepel.br, patricia@cepel.br, dutra@cepel.br

    2007-07-01

    The Centro de Referencia para as Energias Solar e Eolica Sergio de Salvo Brito - CRESESB was created in late 1994 through a agreement between CEPEL and the Ministry of Mines and Energy, at the recommendation of the 'Declaration of Belo Horizonte'. In 10 years of activities, CRESESB / CEPEL has developed several studies, the most important: support for various government programs of the MME and the MCT, Internet dissemination of information, assembling and running courses in solar energy and wind power, edition of publications, maintenance of a specialized library and visits to 'Casa Solar Eficiente' (Efficient Solar House). Other activities also include: attendance at meetings, participation in working groups, reporting, feasibility studies, installation and support of numerous events, etc.. The aim of this paper is to present the scientific community of solar and wind power a historical record of 10 years of activities developed by CRESESB, an assessment of achievements and planned targets for the future.

  20. Effect of gender and lean body mass on kidney size in healthy 10-year-old children

    DEFF Research Database (Denmark)

    Schmidt, I M; Mølgaard, C; Main, K M

    2001-01-01

    When evaluating renal abnormalities, kidney volume is an important parameter. Most reference materials on kidney size in children are based on data from pediatric patients examined for non-uronephrological problems. Renal size is traditionally related to body height, weight, or surface area......, but not to body composition. As part of a prospective cohort study we have examined 102 healthy 10-year-old children measuring kidney volume by ultrasonography, body composition by dual energy X-ray absorptiometry, and body height and weight. Boys had significantly larger kidneys than girls. The strongest....... In conclusion, the strongest predictor of kidney volume in healthy 10-year-old children is lean body mass. The correlation is likely to reflect an association between metabolic active tissue, renal solute load, and kidney volume. We have currently no explanation for the negative correlation between fat body...

  1. Validity and Reliability of the TGMD-2 in 7-10-Year-Old Flemish Children with Intellectual Disability

    Science.gov (United States)

    Simons, Johan; Daly, Daniel; Theodorou, Fani; Caron, Cindy; Simons, Joke; Andoniadou, Elena

    2008-01-01

    The purpose of this study was to assess validity and reliability of the TGMD-2 on Flemish children with intellectual disability. The total sample consisted of 99 children aged 7-10 years of which 67 were boys and 32 were girls. A factor analysis supported a two factor model of the TGMD-2. A low significant age effect was also found for the object…

  2. Rheumatoid arthritis patients with continued low disease activity have similar outcomes over 10 years, regardless of initial therapy.

    Science.gov (United States)

    Bergstra, Sytske Anne; Landewé, Robert B M; Huizinga, Tom W J; Allaart, Cornelia F

    2017-10-01

    To compare 10-year disease outcomes of RA patients who have continuous low disease activity and are on MTX with or without initial combination therapy with infliximab or prednisone and SSZ. Recent-onset RA patients from the Behandel Strategieen (BeSt) (Dutch acronym for Treatment Strategies) study with 10 years of follow-up were analysed. Treatment was tightly controlled, targeted at DAS ⩽ 2.4. The selected patients had low disease activity from 6 months until 10 years and therefore did not intensify treatment. Patients were grouped into those receiving MTX monotherapy and those receiving initial combination therapy. Between-group differences over time were compared, using (generalized) linear mixed model analyses, for the outcomes DAS, HAQ, ESR, visual analogue scale patient global health, percentage of patients in (drug-free) remission and percentage of patients with Sharp/van der Heijde score progression ⩾5. At 10 years, 28/247 (11%) patients on MTX monotherapy (some tapered to drug free) had continued DAS ⩽ 2.4 compared with 68/261 (26%) patients on combination therapy (all tapered to monotherapy or drug free). No between-group differences in continuous responders were found over time, except for a higher percentage of patients in drug-free remission after MTX monotherapy. Significant group-time interactions were found for DAS, ESR and visual analogue scale patient global health, but the results seem clinically negligible. More patients achieved continuous low disease activity on initial prednisone or infliximab combination therapy than on initial MTX monotherapy, but there appeared to be no additional benefits. Regardless of induction therapy, patients with continuous low disease activity have similar long-term outcomes, with only a higher proportion of patients in drug-free remission after MTX monotherapy.

  3. Bibliometric analysis of scientific articles published in Brazilian and international orthodontic journals over a 10-year period

    OpenAIRE

    Neudí Antonio Primo; Vivian Bertoglio Gazzola; Bruno Tochetto Primo; Maximiano Ferreira Tovo; Italo Medeiros Faraco Junior

    2014-01-01

    Objective: This study aimed at describing the profiles of Brazilian and international studies published in orthodontic journals. Methods: The sample comprised 635 articles selected from two scientific journals, i.e., Dental Press Journal of Orthodontics and American Journal of Orthodontics and Dentofacial Orthopedics, which were analyzed at three different intervals over a 10-year period (1999 - 2004 - 2009). Articles were described in terms of knowledge domain, study design, and country...

  4. Factors Associated with Overweight and Obesity among Kuwaiti Elementary Male School Children Aged 6–10 Years

    OpenAIRE

    Abdulwahab Naser Al-Isa; Jennifer Campbell; Ediriweera Desapriya

    2010-01-01

    Background. Childhood obesity is becoming a global epidemic which may result in increased morbidity and mortality during young adulthood. Objectives. To identify factors associated with overweight and that of obesity among Kuwaiti elementary male school children aged 6–10 years. Methods. Weights and heights of 662 students at a randomly selected school were collected to obtain body mass index (BMI). Results. The prevalence of overweight and obesity among the students were 20.2% and 16.8...

  5. Hemodynamic function of the standard St. Jude bileaflet disc valve has no clinical impact 10 years after aortic valve replacement

    DEFF Research Database (Denmark)

    Lund, Ole; Dorup, Inge; Emmertsen, Kristian

    2005-01-01

    OBJECTIVES: Size mismatch and impaired left ventricular function have been shown to determine the hemodynamic function of the standard St. Jude bileaflet disc valve early after aortic valve replacement (AVR). We aimed to analyse St. Jude valve hemodynamic function and its clinical impact in the s......OBJECTIVES: Size mismatch and impaired left ventricular function have been shown to determine the hemodynamic function of the standard St. Jude bileaflet disc valve early after aortic valve replacement (AVR). We aimed to analyse St. Jude valve hemodynamic function and its clinical impact...... in the survivors of a prospective series 10 years after AVR for aortic stenosis. DESIGN: Forty-three survivors aged 32-90 years from a prospective series attended a follow-up study with Doppler echo and radionuclide cardiography 10 years after AVR for aortic stenosis. Six patients with significant left sided valve......Hg. In a multilinear regression analysis GOA indexed for LVEDD, hypertension, and LVEF were independently related to peak gradient. CONCLUSION: High gradients of the standard St. Jude bileaflet disc valve 10 years after AVR was primarily related to systemic hypertension and mismatch between valve and left ventricular...

  6. Predicting 10-Year Risk of Fatal Cardiovascular Disease in Germany: An Update Based on the SCORE-Deutschland Risk Charts

    Science.gov (United States)

    Rücker, Viktoria; Keil, Ulrich; Fitzgerald, Anthony P; Malzahn, Uwe; Prugger, Christof; Ertl, Georg; Heuschmann, Peter U; Neuhauser, Hannelore

    2016-01-01

    Estimation of absolute risk of cardiovascular disease (CVD), preferably with population-specific risk charts, has become a cornerstone of CVD primary prevention. Regular recalibration of risk charts may be necessary due to decreasing CVD rates and CVD risk factor levels. The SCORE risk charts for fatal CVD risk assessment were first calibrated for Germany with 1998 risk factor level data and 1999 mortality statistics. We present an update of these risk charts based on the SCORE methodology including estimates of relative risks from SCORE, risk factor levels from the German Health Interview and Examination Survey for Adults 2008–11 (DEGS1) and official mortality statistics from 2012. Competing risks methods were applied and estimates were independently validated. Updated risk charts were calculated based on cholesterol, smoking, systolic blood pressure risk factor levels, sex and 5-year age-groups. The absolute 10-year risk estimates of fatal CVD were lower according to the updated risk charts compared to the first calibration for Germany. In a nationwide sample of 3062 adults aged 40–65 years free of major CVD from DEGS1, the mean 10-year risk of fatal CVD estimated by the updated charts was lower by 29% and the estimated proportion of high risk people (10-year risk > = 5%) by 50% compared to the older risk charts. This recalibration shows a need for regular updates of risk charts according to changes in mortality and risk factor levels in order to sustain the identification of people with a high CVD risk. PMID:27612145

  7. Genetic contributions to age-related decline in executive function: a 10-year longitudinal study of COMT and BDNF polymorphisms

    Directory of Open Access Journals (Sweden)

    Kirk I Erickson

    2008-09-01

    Full Text Available Genetic variability in the dopaminergic and neurotrophic systems could contribute to age-related impairments in executive control and memory function. In this study we examined whether genetic polymorphisms for catechol-O-methyltransferase (COMT and brain-derived neurotrophic factor (BDNF were related to the trajectory of cognitive decline occurring over a 10-year period in older adults. A single-nucleotide polymorphism (SNP in the COMT (Val158/108Met gene affects the concentration of dopamine in the prefrontal cortex. In addition, a Val/Met substitution in the pro-domain for BDNF (Val66Met affects the regulated secretion and trafficking of BDNF with Met carriers showing reduced secretion and poorer cognitive function. We found that impairments over the 10-year span on a task-switching paradigm did not vary as a function of the COMT polymorphism. However, for the BDNF polymorphism the Met carriers performed worse than Val homozygotes at the first testing session but only the Val homozygotes demonstrated a significant reduction in performance over the 10-year span. Our results argue that the COMT polymorphism does not affect the trajectory of age-related executive control decline, whereas the Val/Val polymorphism for BDNF may promote faster rates of cognitive decay in old age. These results are discussed in relation to the role of BDNF in senescence and the transforming impact of the Met allele on cognitive function in old age.

  8. Persistence of 10-year old Exxon Valdez oil on Gulf of Alaska beaches: The importance of boulder-armoring

    Energy Technology Data Exchange (ETDEWEB)

    Irvine, G.V. [United States Geological Survey , Anchorage, AK (United States); Mann, D.H. [University of Alaska, Fairbanks, AK (United States). Institute of Arctic Biology; Short, J.W. [National Oceanic and Atmospheric Administration, Juneau, AK (United States). Auke Bay Fisheries Laboratory

    2006-09-15

    Oil stranded as a result of the 1989 Exxon Valdez spill has persisted for >10 years at study sites on Gulf of Alaska shores distant from the spill's origin. These sites were contaminated by 'oil mousse', which persists in these settings due to armoring of underlying sediments and their included oil beneath boulder. The boulder-armored beaches that we resampled in 1999 showed continued contamination by subsurface oil, despite their exposure to moderate to high wave energies. Significant declines in surface oil cover occurred at all study sites. In contrast, mousse has persisted under boulders in amounts similar to what was present in 1994 and probably in 1989. Especially striking is the general lack of weathering of this subsurface oil over the last decade. Oil at five of the six armored-beach sites 10 years after the spill is compositionally similar to 11-day old Exxon Valdez oil. Analysis of movements in the boulder-armor that covers the study beaches reveals that only minor shifts have occurred since 1994, suggesting that over the last five, and probably over the last 10 years, boulder-armors have remained largely unmoved at the study sites. These findings emphasize the importance of particular geomorphic parameters in determining stranded oil persistence. Surface armoring, combined with stranding of oil mousse, results in the unexpectedly lengthy persistence of only lightly to moderately weathered oil within otherwise high-energy wave environments. (author)

  9. ENLIGHT 10 year Anniversary

    CERN Multimedia

    Alvarez, Paul

    2012-01-01

    Ten years ago, in February 2002, the European Network for Light Ion Hadron Therapy (ENLIGHT) had its inaugural meeting at CERN. As a pioneering multidisciplinary network celebrates its 10th anniversary, some of the founders recall how it all started. Picture 1 : Participants at the 10th anniversary meeting of ENLIGHT at CNAO, Pavia, in September 2012.

  10. Diet & Nutrition

    Science.gov (United States)

    ... Giving d Employer Matching Gifts d Gifts of Stock or Securities d Giving Circles Golden Circle Circle ... health. Shelly Diagnosed in 2006 Diet & Nutrition Take Control of Your Weight Portion Control Low Carb Omega- ...

  11. Parenteral nutrition

    National Research Council Canada - National Science Library

    Inayet, N; Neild, P

    2015-01-01

    Over the last 50 years, parenteral nutrition has been recognised as an invaluable and potentially lifesaving tool in the physician's arsenal in the management of patients with intestinal failure or inaccessibility...

  12. Nutritional anemias.

    Science.gov (United States)

    Oski, F A

    1979-10-01

    The role of the metals, iron and copper, and the vitamins E, folic acid, and B12 in the genesis of nutritional anemias in infancy have been reviewed. All are preventable. The precise requirements for each of these trace elements and vitamins in the small premature infant remain to be defined. The nonhematologic consequences of these nutritional deficiencies require further study. Anemia may prove to be the least important manifestation of the deficiency states.

  13. Where Is Needle- and Root-Derived Soil Organic Matter After 10 Years of Decomposition in a Temperate Forest?

    Science.gov (United States)

    Hicks Pries, C.; Hatton, P.; Castanha, C.; Bird, J. A.; Torn, M. S.

    2013-12-01

    All soil organic matter (SOM) is ultimately derived from plant litter. The fate of plant litter in ecosystems determines soil carbon (C) storage and nutrient availability with far-reaching implications for ecosystems and global change. However, little is known about the process by which litter becomes SOM (as opposed to the well-studied controls on rates of C and nitrogen (N) loss from litter). We are investigating whether litter type affects where in soils litter-derived C and N eventually reside. Specifically, we are investigating whether litter type affects which minerals the C and N are associated with and how much C is in the microbial pool after a decade. We incubated 15N and 13C-labeled Pinus ponderosa needle and fine root litter in the Blodgett Experimental Forest in the Sierra Nevada foothills for 10 years. A two-way factorial design was used with needle and root litter placed into O and A soil horizons. In 2001, litter was inserted into the given horizon within soil mesocosms (10.2 cm diameter x 24 cm long PVC) that had two 5 x 5 cm mesh windows to allow contact with the surrounding soil. After 0.5, 1, 1.5, 4.5, and 10 years, the soil mesocosms were collected from the field. Isotopes were used to measure the percent recovery of the litter C and N in the bulk soil of the O and A horizons. To investigate mineral associations of the added litter C and N after 10 years, we sequentially fractionated the soils by density. The fractions were a free light fraction (2.78 g cm-3). To quantify the amount of litter-derived C actively cycling in the microbial pool after 10 years and use of the C by different microbial groups, we measured the 13C in phospholipid fatty acids (PLFAs). After 10 years, more root litter C (about 40%) was retained in the soil than needle litter C (about 25%). Less than 0.15% of the remaining litter C (0.06% of originally applied) was found actively cycling in microbial PLFA's. Needle and root C did not differ in the amount remaining still in

  14. Space Nutrition

    Science.gov (United States)

    Smith, Scott M.

    2009-01-01

    Optimal nutrition will be critical for crew members who embark on space exploration missions. Nutritional assessment provides an opportunity to ensure that crewmembers begin their missions in optimal nutritional status, to document changes during a mission and, if necessary, to provide intervention to maintain that status throughout the mission, and to assesses changes after landing in order to facilitate the return to their normal status as soon as possible after landing. We report here the findings from our nutritional assessment of astronauts who participated in the International Space Station (ISS) missions, along with flight and ground-based research findings. We also present ongoing and planned nutrition research activities. These studies provide evidence that bone loss, compromised vitamin status, and oxidative damage are the critical nutritional concerns for space travelers. Other nutrient issues exist, including concerns about the stability of nutrients in the food system, which are exposed to longterm storage and radiation during flight. Defining nutrient requirements, and being able to provide and maintain those nutrients on exploration missions, will be critical for maintaining crew member health.

  15. Nutrition intervention in scholars

    Directory of Open Access Journals (Sweden)

    Carolina Anzolin

    2010-12-01

    Full Text Available Objective: To verify the effectiveness of nutrition intervention in changing dietary intake among school children aged 6 to 10 years old in private school, in the city of Itajaí - SC, Brazil. Methods: A non-randomized and uncontrolled intervention study, carried through four educational activities in the period from August to November, 2008 and food intake reassessed at the end. We evaluated the nutritional status by means of body mass index for age and sex, and waist circumference. The frequency of consumption before and after intervention was compared using the paired Student t test. Results: Joined in the survey 93 students (69.92% of whom 48 children (54.5% were normal weight, while 36 (40.9% were overweight or presented obesity. The most consumed food groups, before and after intervention were: crackers and pasta; rice and fruit juice. The average frequency of sweets intake decreased after the intervention (0.54 to 0.24 times per day, p <0.001, however increased the intake of fried potatoes (0.25 to 0.65, p <0.001, pizza and hamburger (0.30 to 0.46, p = 0.028. Among girls, the intake of sweets decreased after the educational activities (0.58 to 0.12, p <0.001. Conclusions: Nutritional interventions, despite the short period of time, were effective in changing the consumption of certain foods / food groups. The results reinforce the need to carry out interventions more often and for longer periods, to promote effective changes in food consumption.

  16. Comparison of ACR 1987 and ACR/EULAR 2010 criteria for predicting a 10-year diagnosis of rheumatoid arthritis.

    Science.gov (United States)

    Cornec, Divi; Varache, Sophie; Morvan, Johanne; Devauchelle-Pensec, Valérie; Berthelot, Jean-Marie; Le Henaff-Bourhis, Catherine; Hoang, Sylvie; Martin, Antoine; Chalès, Gérard; Jousse-Joulin, Sandrine; Saraux, Alain

    2012-12-01

    To compare the diagnostic accuracy of the 2010 American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) and 1987 ACR criteria for rheumatoid arthritis (RA) in a cohort of patients with recent-onset arthritis followed-up for 10 years. One hundred and sixty-four patients with recent-onset arthritis of less than 1 year's duration were included prospectively between 1995 and 1997. The diagnosis of RA was defined as having a diagnosis of RA made by the office-based rheumatologist 10 years after enrolment. We compared the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of the criteria sets at baseline. At baseline, 60 of the 164 patients had alternative diagnoses better explaining the arthritis and 13 had erosions typical for RA; of the 91 remaining patients, 33 had at least 6 ACR/EULAR points (indicating definite RA), and 58 had fewer than 6 points. The ACR/EULAR criteria had a quite similar sensitivity than the 1987 ACR criteria (33/57 [57.9%] for ACR/EULAR criteria vs 34/57 [59.6%] for the 1987 ACR criteria), but higher specificity, PPV, and NPV (95/107 [88.8%], 34/46 [73.9%], and 95/118 [80.5%], respectively) than the 1987 ACR criteria (80/107 [74.8%], 33/63 [52.4%], and 80/104 [76.9%], respectively). ACR/EULAR criteria performed substantially better than ACR 1987 criteria for predicting a diagnosis of RA after 10 years. Much of the improvement was ascribable to the use of exclusion criteria. BULLET POINTS: (1) The ACR/EULAR criteria had the same sensitivity, but higher specificity, PPV, and NPV than the 1987 ACR criteria; (2) Much of the improvement was ascribable to the use of exclusion criteria. Copyright © 2012 Société française de rhumatologie. Published by Elsevier SAS. All rights reserved.

  17. Long Term Clinical Prognostic Factors in Relapsing-Remitting Multiple Sclerosis: Insights from a 10-Year Observational Study.

    Directory of Open Access Journals (Sweden)

    Gabriel Bsteh

    Full Text Available Multiple sclerosis (MS has a highly heterogenic course making prediction of long term outcome very difficult.The objective was to evaluate current and identify additional clinical factors that are linked to long term outcome of relapsing-remitting MS assessed by disability status 10 years after disease onset.This observational study included 793 patients with relapsing-remitting MS. Clinical factors hypothesized to influence long term outcome measured by EDSS scores 10 years after disease onset were analysed by Kaplan-Meier-estimates. Multinomial logistic regression models regarding mild (EDSS ≤2.5, moderate (EDSS 3.0-5.5 or severe (EDSS ≥6.0 disability were calculated to correct for confounders.Secondary progression was the strongest predictor of severe disability (Hazard ratio [HR] 503.8, 95% confidence interval [CI] 160.0-1580.1; p<0.001. Complete remission of neurological symptoms at onset reduced the risk of moderate disability (HR 0.42; CI 0.23-0.77; p = 0.005, while depression (HR 3.59; CI 1.14-11.24; p = 0.028 and cognitive dysfunction (HR 4.64; CI 1.11-19.50; p = 0.036 10 years after disease onset were associated with severe disability. Oligoclonal bands and pregnancy were not correlated with disability.We were able to identify clinically apparent chronic depression and cognitive dysfunction to be associated with adverse long term outcome in MS and to confirm that pregnancy has no negative impact. Additionally, we emphasize the positive predictive value of complete remission of initial symptoms.

  18. The 10-Year Local Recurrence and Partial Breast Radiotherapy for Early Breast Cancer Treated by Conservative Surgery

    Institute of Scientific and Technical Information of China (English)

    Zhizhen Wang; Ruiying Li

    2006-01-01

    OBJECTIVE To study the local recurrence and the role of whole breast radiotherapy for early breast cancer treated by conservative surgery.METHODS From April 1990 to December 2000, 49 patients with early primary breast cancer were treated by conservative surgery in our hospital. The cases were comprised of Stage 0, 1; Stage Ⅰ, 31; and Stage Ⅱa,17. Forty cases underwent quadrantectomy plus axillary lymph node dissection, and the other 9 cases had lumpectomy alone. Irradiation, which was received by 39 patients, was administered by using low tangential half fields with 6 MV X-ray to decrease the pulmonary irradiative volume.The dose to the whole breast was 45 Gy/22~23f/4.5W, then a 15 Gy boost dose was delivered to the tumor bed by an electron beam. The other patients underwent an irradiated regional field according to postoperative pathology.RESULTS All patients were followed-up for 10 years or more. The 10year local recurrence rates, distant metastasis rates and survival rates were 6.1%, 4.1% and 98.0% respectively. All of the 3 patients who had a local recurrence had infiltrative carcinomas and negative lymph nodes.The 10-year local recurrence rate was higher (2.6% vs. 20.0%) with nonpostoperative whole breast radiotherapy, but the statistical difference was not marked because of the low number of cases. All of the recurrent lesions localized within 3 cm of the primary lesion.CONCLUSION Original recurrence of the tumor was the main type of local recurrence. Radiotherapy after conservative surgery is very essential.After conservative surgery it is feasible that irradiation can be delivered alone to the neighboring region of the tumor bed. Partial breast radiotherapy can substitute for whole breast radiotherapy.

  19. Radiostereometric migration measurement of an uncemented Cerafit® femoral stem: 26 patients followed for 10 years.

    Science.gov (United States)

    Sesselmann, Stefan; Hong, Yotung; Schlemmer, Frank; Hussnaetter, Isabell; Mueller, Lutz A; Forst, Raimund; Tschunko, Franz

    2017-08-18

    Radiostereometric analysis (RSA) is the gold standard for evaluating micromotions of orthopaedic implants. The method is applied for identifying novel design weaknesses in endoprostheses. Current research frequently assesses relatively short time periods. Short-term RSA studies have been widely used for predicting the long-term stability of many hip prosthetic designs, but only a few studies have focused on uncemented hip implants, especially for extended periods. The purpose of this study was to analyse the migration pattern of the Cerafit® femoral stem within 10 years and to verify the predictive value of short-term RSA after 2 years for this uncemented femoral hip stem. Twenty-six patients were followed for 10 years. Ten years after implantation, a mean subsidence of 0.22 mm±0.56 mm, a mean internal rotation of 0.59°±1.67° and a mean maximum total point motion (MTPM) of 1.28 mm±0.54 mm were detected. The main migration took place in the first 6 weeks after surgery (subsidence of 0.36 mm±0.73 mm; internal rotation of 0.62°±1.49°, MTPM of 1.05 mm±0.68 mm). All the migration values measured were small. No late-onset migration was observed. This study suggests that the Cerafit® implants are stable after 10 years. Thus, RSA could be the best tool to assess long-term implant behaviour.

  20. Education status determines 10-year (2002-2012) survival from cardiovascular disease in Athens metropolitan area: the ATTICA study, Greece.

    Science.gov (United States)

    Panagiotakos, Demosthenes; Georgousopoulou, Ekavi; Notara, Venetia; Pitaraki, Evangelia; Kokkou, Eleni; Chrysohoou, Christina; Skoumas, Yannis; Metaxa, Vassiliki; Pitsavos, Christos; Stefanadis, Christodoulos

    2016-05-01

    Cardiovascular disease (CVD) remains the leading cause of morbidity and mortality worldwide, and educational level seems to be an important determinant of the disease occurrence. The aim of this work was to investigate the association between education status and 10-year incidence of CVD, controlling for various socio-demographic lifestyle and clinical factors. From May 2001 to December 2002, 1514 men and 1528 women (>18 years) without any clinical evidence of CVD or any other chronic disease, at baseline, living in greater Athens area, Greece, were enrolled. In 2011-2012, the 10-year follow-up was performed in 2583 participants (15% of the participants were lost to follow-up). Incidence of fatal or non-fatal CVD was defined according to WHO-ICD-10 criteria. Education status was measured in years of schooling. The 10-year incidence of CVD was 15.7% [95% confidence intervals (CI) 14.1%-17.4%], 19.7% in men and 11.7% in women (Pgender education (education (>12 years of schooling). People in the low education group had higher prevalence of hypertension, diabetes and dyslipidaemias, were more likely to be smokers and sedentary, had less healthy dietary habits, as compared with those in the high education group. When controlling for participants' medical history, smoking, dietary and lifestyle habits, low education was no longer significantly associated with CVD, illustrating the mediating effect of clinical and behavioural factors in the link between education and disease. It was of interest that low education status interacted with alcohol drinking, enhancing the adverse effect of low education on CVD risk (relative risk 1.44, 95% CI 0.94%-2.20%), after various adjustments made. In this study, it was concluded that low educational level was associated with increased CVD risk. This was mainly explained by the intermediate association of low education with unhealthy choices that consequently worsen clinical status.