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Sample records for 10-week randomized hypo-energetic

  1. Macronutrient-specific effect of FTO rs9939609 in response to a 10-week randomized hypo-energetic diet among obese Europeans

    DEFF Research Database (Denmark)

    Grau, K; Hansen, T; Holst, C;

    2009-01-01

    BACKGROUND: The A risk allele of rs9939609 of the fat mass- and obesity-associated gene (FTO) increases body fat mass. OBJECTIVE: To examine whether FTO rs9939609 affects obese individuals' response to a high-fat, low-carbohydrate (CHO) (HF) or low-fat, high-CHO (LF), hypo-energetic diet......-energetic diet (measured resting metabolic rate multiplied by 1.3-600 kcal day(-1)). Body weight, fat mass (FM), fat-free mass (FFM), waist circumference (WC), resting energy expenditure (REE), fasting fat oxidation as % of REE (FatOx), insulin release (HOMA-beta) and a surrogate measure of insulin resistance...... (HOMA-IR) were measured at baseline and after the intervention. In all, 764 individuals were genotyped for FTO rs9939609. RESULTS: For A-allele carriers the drop-out rate was higher on HF than LF diet (in AT, P=0.002; in AT/AA combined, P=0.003). Among those individuals completing the intervention, we...

  2. Lithium trial in Alzheimer's disease: a randomized, single-blind, placebo-controlled, multicenter 10-week study.

    LENUS (Irish Health Repository)

    Hampel, Harald

    2012-02-01

    OBJECTIVE: Lithium, a first-line drug for the treatment of bipolar depression, has recently been shown to regulate glycogen synthase kinase-3 (GSK-3), a kinase that is involved in the phosphorylation of the tau protein. Since hyperphosphorylation of tau is a core pathological feature in Alzheimer\\'s disease, lithium-induced inhibition of GSK-3 activity may have therapeutic effects in Alzheimer\\'s disease. In the current study, we tested the effect of short-term lithium treatment in patients with Alzheimer\\'s disease. METHOD: A total of 71 patients with mild Alzheimer\\'s disease (Mini-Mental State Examination score > or = 21 and < or = 26) were successfully randomly assigned to placebo (N = 38) or lithium treatment (N = 33) at 6 academic expert memory clinics. The 10-week treatment included a 6-week titration phase to reach the target serum level of lithium (0.5-0.8 mmol\\/L). The primary outcome measures were cerebrospinal fluid (CSF) levels of phosphorylated tau (p-tau) and GSK-3 activity in lymphocytes. Secondary outcome measures were CSF concentration of total tau and beta-amyloid(1-42) (Abeta(1-42)), plasma levels of Abeta(1-42), Alzheimer\\'s Disease Assessment Scale (ADAS)-Cognitive summary scores, MMSE, and Neuropsychiatric Inventory (NPI). Patients were enrolled in the study from November 2004 to July 2005. RESULTS: No treatment effect on GSK-3 activity or CSF-based biomarker concentrations (P > .05) was observed. Lithium treatment did not lead to change in global cognitive performance as measured by the ADAS-Cog subscale (P = .11) or in depressive symptoms. CONCLUSIONS: The current results do not support the notion that lithium treatment may lead to reduced hyperphosphorylation of tau protein after a short 10-week treatment in the Alzheimer\\'s disease target population. TRIAL REGISTRATION: (Controlled-Trials.com) Identifier: ISRCTN72046462.

  3. Allelic variants of melanocortin 3 receptor gene (MC3R and weight loss in obesity: a randomised trial of hypo-energetic high- versus low-fat diets.

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    José L Santos

    Full Text Available INTRODUCTION: The melanocortin system plays an important role in energy homeostasis. Mice genetically deficient in the melanocortin-3 receptor gene have a normal body weight with increased body fat, mild hypophagia compared to wild-type mice. In humans, Thr6Lys and Val81Ile variants of the melanocortin-3 receptor gene (MC3R have been associated with childhood obesity, higher BMI Z-score and elevated body fat percentage compared to non-carriers. The aim of this study is to assess the association in adults between allelic variants of MC3R with weight loss induced by energy-restricted diets. SUBJECTS AND METHODS: This research is based on the NUGENOB study, a trial conducted to assess weight loss during a 10-week dietary intervention involving two different hypo-energetic (high-fat and low-fat diets. A total of 760 obese patients were genotyped for 10 single nucleotide polymorphisms covering the single exon of MC3R gene and its flanking regions, including the missense variants Thr6Lys and Val81Ile. Linear mixed models and haplotype-based analysis were carried out to assess the potential association between genetic polymorphisms and differential weight loss, fat mass loss, waist change and resting energy expenditure changes. RESULTS: No differences in drop-out rate were found by MC3R genotypes. The rs6014646 polymorphism was significantly associated with weight loss using co-dominant (p = 0.04 and dominant models (p = 0.03. These p-values were not statistically significant after strict control for multiple testing. Haplotype-based multivariate analysis using permutations showed that rs3827103-rs1543873 (p = 0.06, rs6014646-rs6024730 (p = 0.05 and rs3746619-rs3827103 (p = 0.10 displayed near-statistical significant results in relation to weight loss. No other significant associations or gene*diet interactions were detected for weight loss, fat mass loss, waist change and resting energy expenditure changes. CONCLUSION: The study

  4. Clinical correlates of weight loss and attrition during a 10-week dietary intervention study

    DEFF Research Database (Denmark)

    Handjieva-Darlenska, Teodora; Holst, Claus; Grau, Katrine;

    2012-01-01

    Objective: The aim of this study was to identify the pre-treatment subject characteristics and weight loss changes as determinants of weight loss and attrition during a 10-week dietary intervention study. Methods: A total of 771 obese subjects (BMI 35.6 kg/m(2)) of both genders were included from 8...... clinical centres in 7 European countries, who underwent a 10-week dietary intervention study comparing two hypo-energetic (-600 kcal/day) diets varying in fat content. Results: The multiple regression model showed that weight loss at week 10 was predicted by: 6.55 + 1.27 × early weight loss (kg) at week 1...

  5. Randomized, multi-center trial of two hypo-energetic diets in obese subjects: high- versus low-fat content

    DEFF Research Database (Denmark)

    Petersen, M; Taylor, M A; Saris, W H M;

    2006-01-01

    and 40% in the high-fat group (mean difference: 16 (95% confidence interval (CI) 15-17)%). Average weight loss was 6.9 kg in the low-fat group and 6.6 kg in the high-fat group (mean difference: 0.3 (95% CI -0.2 to 0.8) kg). Dropout was 13.6% (n = 53) in the low-fat group and 18.3% (n = 70) in the high...

  6. Rabies in a 10-week-old puppy.

    Science.gov (United States)

    White, Jennifer; Taylor, Susan M; Wolfram, Kathrin L; O'Conner, Brendan P

    2007-09-01

    A 10-week-old, male, border collie-cross puppy was examined for an acute onset of unilateral vestibular signs. Neurologic deterioration was rapid over the next 12 hours and the puppy was euthanized. Rabies was diagnosed by histopathologic and immunohistochemical examination. PMID:17966334

  7. Structural and functional cardiac adaptations to a 10-week school-based football intervention for 9-10-year-old children

    DEFF Research Database (Denmark)

    Krustrup, Peter; Hansen, Peter Riis; Nielsen, Claus Malta;

    2014-01-01

    The present study investigated the cardiac effects of a 10-week football training intervention for school children aged 9-10 years using comprehensive transthoracic echocardiography as a part of a larger ongoing study. A total of 97 pupils from four school classes were cluster-randomized into a c...

  8. Identifying the limitations for growth in low performing piglets from birth until 10 weeks of age.

    Science.gov (United States)

    Paredes, S P; Jansman, A J M; Verstegen, M W A; den Hartog, L A; van Hees, H M J; Bolhuis, J E; van Kempen, T A T G; Gerrits, W J J

    2014-06-01

    The evolution of hyper-prolific pig breeds has led to a higher within-litter variation in birth weight and in BW gain during the nursery phase. Based on an algorithm developed in previous research, two populations from a pool of 368 clinically healthy piglets at 6 weeks of age were selected: a low (LP) and a high (HP) performing population and their development was monitored until the end of the nursery phase (10 weeks of age). To understand the cause of the variation in growth between these populations we characterized the LP and HP piglets in terms of body morphology, behaviour, voluntary feed intake, BW gain, and apparent total tract and ileal nutrient digestibility. Piglets were housed individually and were fed a highly digestible diet. At selection, 6 weeks of age, the BW of LP and HP piglets were 6.8±0.1 and 12.2±0.1 kg, respectively. Compared with the LP piglets the HP piglets grew faster (203 g/day), ate more (275 g/day) from 6 to 10 weeks of age and were heavier at 10 weeks (30.0 v. 18.8 kg, all Pratio was similar for both groups. LP piglets tended to take more time to touch a novel object (P=0.10), and spent more time eating (Pbody length and head circumference relative to BW (Pweight; 36% longer length, and relative to average FI, the small intestinal weight was 4 g/kg higher (both P=0.10). We concluded that the low performance of the LP piglets was due to their inability to engage compensatory gain or compensatory feed intake as efficiency of nutrient utilization and feed intake per kg BW0.75 was unaffected. LP piglets tend to be more fearful towards novel objects. The morphological comparisons, increased body length and head circumference relative to BW imply that LP piglets have an increased priority for skeletal growth. PMID:24679743

  9. Effect of 10 Week Beta-Alanine Supplementation on Competition and Training Performance in Elite Swimmers

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    Louise M. Burke

    2012-10-01

    Full Text Available Although some laboratory-based studies show an ergogenic effect with beta-alanine supplementation, there is a lack of field-based research in training and competition settings. Elite/Sub-elite swimmers (n = 23 males and 18 females, age = 21.7 ± 2.8 years; mean ± SD were supplemented with either beta-alanine (4 weeks loading phase of 4.8 g/day and 3.2 g/day thereafter or placebo for 10 weeks. Competition performance times were log-transformed, then evaluated before (National Championships and after (international or national selection meet supplementation. Swimmers also completed three standardized training sets at baseline, 4 and 10 weeks of supplementation. Capillary blood was analyzed for pH, bicarbonate and lactate concentration in both competition and training. There was an unclear effect (0.4%; ±0.8%, mean, ±90% confidence limits of beta-alanine on competition performance compared to placebo with no meaningful changes in blood chemistry. While there was a transient improvement on training performance after 4 weeks with beta-alanine (−1.3%; ±1.0%, there was an unclear effect at ten weeks (−0.2%; ±1.5% and no meaningful changes in blood chemistry. Beta-alanine supplementation appears to have minimal effect on swimming performance in non-laboratory controlled real-world training and competition settings.

  10. Effects of a 10-Week High-Intensity Exercise Intervention on College Staff with Psychological Burnout and Multiple Risk Factors

    Science.gov (United States)

    Dreyer, Lukas; Dreyer, Sonja; Rankin, Dean

    2012-01-01

    This study examined the effect of a 10-week physical exercise program on the health status of college staff. Eighty-one participants were pre-tested on 22 variables including physical fitness, biochemical status, psychological health, and morphological measures. Participants in an experimental group (n = 61) received a 10-week intervention…

  11. A 10-Week Multimodal Nutrition Education Intervention Improves Dietary Intake among University Students: Cluster Randomised Controlled Trial

    Directory of Open Access Journals (Sweden)

    Mohd Razif Shahril

    2013-01-01

    Full Text Available The aim of the study was to evaluate the effectiveness of implementing multimodal nutrition education intervention (NEI to improve dietary intake among university students. The design of study used was cluster randomised controlled design at four public universities in East Coast of Malaysia. A total of 417 university students participated in the study. They were randomly selected and assigned into two arms, that is, intervention group (IG or control group (CG according to their cluster. The IG received 10-week multimodal intervention using three modes (conventional lecture, brochures, and text messages while CG did not receive any intervention. Dietary intake was assessed before and after intervention and outcomes reported as nutrient intakes as well as average daily servings of food intake. Analysis of covariance (ANCOVA and adjusted effect size were used to determine difference in dietary changes between groups and time. Results showed that, compared to CG, participants in IG significantly improved their dietary intake by increasing their energy intake, carbohydrate, calcium, vitamin C and thiamine, fruits and 100% fruit juice, fish, egg, milk, and dairy products while at the same time significantly decreased their processed food intake. In conclusion, multimodal NEI focusing on healthy eating promotion is an effective approach to improve dietary intakes among university students.

  12. Effect of 10-week core stabilization exercise training and detraining on pain-related outcomes in patients with clinical lumbar instability

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    Puntumetakul R

    2013-11-01

    Full Text Available Rungthip Puntumetakul,1,2 Pattanasin Areeudomwong,1,2 Alongkot Emasithi,1 Junichiro Yamauchi3,4 1School of Physical Therapy, Faculty of Associated Medical Sciences, Muang District, Kohn Kaen, Thailand; 2Back, Neck and Other Joint Pain Research Group, Khon Kaen University, Khon Kaen, Thailand; 3Graduate School of Human Health Sciences, Tokyo Metropolitan University, Tokyo, Japan; 4Future Institute for Sport Sciences, Tokyo, Japan Background and aims: Clinical lumbar instability causes pain and socioeconomic suffering; however, an appropriate treatment for this condition is unknown. This article examines the effect of a 10 week core stabilization exercise (CSE program and 3 month follow-up on pain-related outcomes in patients with clinical lumbar instability. Methods: Forty-two participants with clinical lumbar instability of at least 3 months in duration were randomly allocated either to 10 weekly treatments with CSE or to a conventional group (CG receiving trunk stretching exercises and hot pack. Pain-related outcomes including pain intensity during instability catch sign, functional disability, patient satisfaction, and health-related quality of life were measured at 10 weeks of intervention and 1 and 3 months after the last intervention session (follow-up; trunk muscle activation patterns measured by surface electromyography were measured at 10 weeks. Results: CSE showed significantly greater reductions in all pain-related outcomes after 10 weeks and over the course of 3 month follow-up periods than those seen in the CG (P<0.01. Furthermore, CSE enhanced deep abdominal muscle activation better than in the CG (P<0.001, whereas the CG had deterioration of deep back muscle activation compared with the CSE group (P<0.01. For within-group comparison, CSE provided significant improvements in all pain-related outcomes over follow-up (P<0.01, whereas the CG demonstrated reduction in pain intensity during instability catch sign only at 10 weeks (P<0

  13. Impact of 10-weeks of yoga practice on flexibility and balance of college athletes

    Science.gov (United States)

    Polsgrove, M Jay; Eggleston, Brandon M; Lockyer, Roch J

    2016-01-01

    Background: With clearer evidence of its benefits, coaches, and athletes may better see that yoga has a role in optimizing performance. Aims: To determine the impact of yoga on male college athletes (N = 26). Methods: Over a 10-week period, a yoga group (YG) of athletes (n = 14) took part in biweekly yoga sessions; while a nonyoga group (NYG) of athletes (n = 12) took part in no additional yoga activity. Performance measures were obtained immediately before and after this period. Measurements of flexibility and balance, included: Sit-reach (SR), shoulder flexibility (SF), and stork stand (SS); dynamic measurements consisted of joint angles (JA) measured during the performance of three distinct yoga positions (downward dog [DD]; right foot lunge [RFL]; chair [C]). Results: Significant gains were observed in the YG for flexibility (SR, P = 0.01; SF, P = 0.03), and balance (SS, P = 0.05). No significant differences were observed in the NYG for flexibility and balance. Significantly, greater JA were observed in the YG for: RFL (dorsiflexion, l-ankle; P = 0.04), DD (extension, r-knee, P = 0.04; r-hip; P = 0.01; flexion, r-shoulder; P = 0.01) and C (flexion, r-knee; P = 0.01). Significant JA differences were observed in the NYG for: DD (flexion, r-knee, P = 0.01: r-hip, P = 0.05; r-shoulder, P = 0.03) and C (flexion r-knee, P = 0.01; extension, r-shoulder; P = 0.05). A between group comparison revealed the significant differences for: RFL (l-ankle; P = 0.01), DD (r-knee, P = 0.01; r-hip; P = 0.01), and C (r-shoulder, P = 0.02). Conclusions: Results suggest that a regular yoga practice may increase the flexibility and balance as well as whole body measures of male college athletes and therefore, may enhance athletic performances that require these characteristics. PMID:26865768

  14. The Effects of a 10-Week Water Aerobic Exercise on the Resting Blood Pressure in Patients with Essential Hypertension

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    Farahani

    2010-09-01

    Full Text Available Purpose To investigate the effects of a 10-week water aerobic exercise on the resting blood pressure in patients with stage 1 or 2 hypertension referring to Tehran University Clinics. Methods Forty men with stage 1 or 2 essential hypertension were assigned to two groups of intervention [n = 12; aged 48.33±10.74 years (mean±SD] and control [n = 28; aged 46.96±11.58 years (mean±SD]. Subjects in the intervention group participated in a supervised 10-week water aerobic training program of 55 min sessions, 3 days per week on alternate days, while those in the control group were not involved in any regular training program during this period. Blood pressure of the participants was recorded and compared at the beginning and at the end of the study (48 hours after the last training session. Results Exercise lowered systolic blood pressure and mean arterial pressure by 11.71 (95% confidence interval: 5.07 to 18.35 and 5.90 (95% confidence interval: 1.17 to 10.63 mm Hg respectively. The lowering effect of exercise on diastolic blood pressure was neither statistically significant nor clinically important (0.55 mm Hg; P. value = 0.8. There was no significant effect of age, baseline body mass index and stage of hypertension on the exercise-induced changes in blood pressure. Conclusion A 10-week course of water aerobic exercise markedly reduced the systolic and mean arterial blood pressure of patients with essential hypertension and is especially recommended for the obese and the elderly who have orthopedic problems or bronchospasm.

  15. Physical and psychological benefits of once-a-week Pilates exercises in young sedentary women: A 10-week longitudinal study.

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    Tolnai, Nóra; Szabó, Zsófia; Köteles, Ferenc; Szabo, Attila

    2016-09-01

    Pilates exercises have several demonstrated physical and psychological benefits. To date, most research in this context was conducted with symptomatic or elderly people with few dependent measures. The current study examined the chronic or longitudinal effects of very low frequency, once a week, Pilates training on several physical and psychological measures, over a 10-week intervention, in young, healthy, and sedentary women. Further, the study gauged the acute effects of Pilates exercises on positive- and negative affect in 10 exercise sessions. Compared to a control group, the Pilates group exhibited significant improvements in skeletal muscle mass, flexibility, balance, core- and abdominal muscle strength, body awareness, and negative affect. This group also showed favorable changes in positive (22.5% increase) and negative affect (12.2% decrease) in nine out of ten exercise sessions. This work clearly demonstrates the acute and chronic benefits of Pilates training on both physical and psychological measures. It also reveals that even only once a week Pilates training is enough to trigger detectable benefits in young sedentary women. While this frequency is below the required levels of exercise for health, it may overcome the 'lack of time' excuse for not exercising and subsequently its tangible benefits may positively influence one's engagement in more physical activity. PMID:27195456

  16. Vitamin C and E supplementation alters protein signalling after a strength training session, but not muscle growth during 10 weeks of training.

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    Paulsen, G; Hamarsland, H; Cumming, K T; Johansen, R E; Hulmi, J J; Børsheim, E; Wiig, H; Garthe, I; Raastad, T

    2014-12-15

    This study investigated the effects of vitamin C and E supplementation on acute responses and adaptations to strength training. Thirty-two recreationally strength-trained men and women were randomly allocated to receive a vitamin C and E supplement (1000 mg day(-1) and 235 mg day(-1), respectively), or a placebo, for 10 weeks. During this period the participants' training involved heavy-load resistance exercise four times per week. Muscle biopsies from m. vastus lateralis were collected, and 1 repetition maximum (1RM) and maximal isometric voluntary contraction force, body composition (dual-energy X-ray absorptiometry), and muscle cross-sectional area (magnetic resonance imaging) were measured before and after the intervention. Furthermore, the cellular responses to a single exercise session were assessed midway in the training period by measurements of muscle protein fractional synthetic rate and phosphorylation of several hypertrophic signalling proteins. Muscle biopsies were obtained from m. vastus lateralis twice before, and 100 and 150 min after, the exercise session (4 × 8RM, leg press and knee-extension). The supplementation did not affect the increase in muscle mass or the acute change in protein synthesis, but it hampered certain strength increases (biceps curl). Moreover, increased phosphorylation of p38 mitogen-activated protein kinase, Extracellular signal-regulated protein kinases 1 and 2 and p70S6 kinase after the exercise session was blunted by vitamin C and E supplementation. The total ubiquitination levels after the exercise session, however, were lower with vitamin C and E than placebo. We concluded that vitamin C and E supplementation interfered with the acute cellular response to heavy-load resistance exercise and demonstrated tentative long-term negative effects on adaptation to strength training.

  17. A 10-Week Multimodal Nutrition Education Intervention Improves Dietary Intake among University Students: Cluster Randomised Controlled Trial

    OpenAIRE

    Mohd Razif Shahril; Wan Putri Elena Wan Dali; Pei Lin Lua

    2013-01-01

    The aim of the study was to evaluate the effectiveness of implementing multimodal nutrition education intervention (NEI) to improve dietary intake among university students. The design of study used was cluster randomised controlled design at four public universities in East Coast of Malaysia. A total of 417 university students participated in the study. They were randomly selected and assigned into two arms, that is, intervention group (IG) or control group (CG) according to their cluster. T...

  18. Metabolic and growth response of mink (Neovison vison) kits until 10 weeks of age when exposed to different dietary protein provision

    DEFF Research Database (Denmark)

    Larsson, Caroline; Fink, Rikke; Matthiesen, Connie Marianne Frank;

    2012-01-01

    Growth performance and metabolism were investigated in mink kits (n = 210) exposed to the same dietary treatment as their dams (n = 30), i.e. high (HP; 61% of metabolisable energy, ME), medium (MP; 48% of ME) or low (LP; 30% of ME) protein supply, from birth until 10 weeks of age. The kits were w...

  19. A Comparison of Student Outcomes and Overall Retention between a 10-Week Accelerated and a 15-Week Traditional Curriculum in a Postsecondary Apprenticeship Training Program

    Science.gov (United States)

    Adams, Gilbert L.

    2013-01-01

    This ex post facto comparison study of a postsecondary apprenticeship program at a naval ship construction company examined 8 years of academic performance and program completion data for two curricular formats: a 15-week traditional group (1,259 apprentices) and a 10-week accelerated group (736 apprentices). The two groups were investigated to…

  20. The effects of 10 weeks of resistance training combined with beta-alanine supplementation on whole body strength, force production, muscular endurance and body composition.

    Science.gov (United States)

    Kendrick, Iain P; Harris, Roger C; Kim, Hyo Jeong; Kim, Chang Keun; Dang, Viet H; Lam, Thanh Q; Bui, Toai T; Smith, Marcus; Wise, John A

    2008-05-01

    Carnosine (Carn) occurs in high concentrations in skeletal muscle is a potent physico-chemical buffer of H+ over the physiological range. Recent research has demonstrated that 6.4 g x day(-1) of beta-alanine (beta-ala) can significantly increase skeletal muscle Carn concentrations (M-[Carn]) whilst the resultant change in buffering capacity has been shown to be paralleled by significant improvements in anaerobic and aerobic measures of exercise performance. Muscle carnosine increase has also been linked to increased work done during resistance training. Prior research has suggested that strength training may also increase M-[Carn] although this is disputed by other studies. The aim of this investigation is to assess the effect of 10 weeks resistance training on M-[Carn], and, secondly, to investigate if increased M-[Carn] brought about through beta-ala supplementation had a positive effect on training responses. Twenty-six Vietnamese sports science students completed the study. The subjects completed a 10-week resistance-training program whilst consuming 6.4 g x day(-1) of beta-ala (beta-ALG) or a matched dose of a placebo (PLG). Subjects were assessed prior to and after training for whole body strength, isokinetic force production, muscular endurance, body composition. beta-Alanine supplemented subjects increased M-[Carn] by 12.81 +/- 7.97 mmol x kg(-1) dry muscle whilst there was no change in PLG subjects. There was no significant effect of beta-ala supplementation on any of the exercise parameters measured, mass or % body fat. In conclusion, 10 weeks of resistance training alone did not change M-[Carn]. PMID:18175046

  1. The course of pain drawings during a 10-week treatment period in patients with acute and sub-acute low back pain

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    Delaney Heléne

    2006-08-01

    Full Text Available Abstract Background Pain drawings are widely used as an assessment of patients' subjective pain in low back pain patients being considered for surgery. Less work has been done on primary health care patients. Moreover, the possible correlation between pain drawing modalities and other pain assessment methods, such as pain score and functional variables needs to be described. Thus, the objectives were to describe the course of pain drawings during treatment in primary health care for low back pain patients. Methods 160 primary health care outpatients with acute or sub-acute low back pain were studied during 10 weeks of a stay active concept versus manual therapy in addition to the stay active concept. The patients filled out 3 pain drawings each, at baseline and after 5 and 10 weeks of treatment. In addition the patients also reported pain and functional variables during the 3 measurement periods. Results The proportion of areas marked, the mean number of areas marked (pain drawing score, mean number of modalities used (area score, and the proportion of patients with pain radiation all decreased during the 10-week treatment period. Most of the improvement occurred during the first half of the period. The seven different pain modalities in the pain drawing were correlated to pain and functional variables. In case of no radiation some modalities were associated with more pain and disability than others, a finding that grew stronger over time. For patients with pain radiation, the modality differences were smaller and inconsistent. Conclusion Pain modalities are significantly correlated with pain and functional variables. There is a shift from painful modalities to less painful ones over time.

  2. A 10-week memantine treatment in bipolar depression: a case report. Focus on depressive symptomatology, cognitive parameters and quality of life.

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    Strzelecki, Dominik; Tabaszewska, Agnieszka; Barszcz, Zbigniew; Józefowicz, Olga; Kropiwnicki, Paweł; Rabe-Jabłońska, Jolanta

    2013-12-01

    Memantine and other glutamatergic agents have been currently investigated in some off-label indications due to glutamatergic involvement in several psychoneurological disorders. We assumed that memantine similarly to ketamine may positively influence mood, moreover having a potential to improve cognition and general quality of life. We report a case of a 49-year-old male hospitalized during a manic and a subsequent moderate depressive episode. After an ineffective use of lithium, olanzapine and antidepressive treatment with mianserin, memantine was added up to 20 mg per day for 10 weeks. The mental state was assessed using the Hamilton Depression Rating Scale, the Young Mania Rating Scale, the Hamilton Anxiety Scale, the Clinical Global Inventory, the World Health Organization Quality of Life Scale and psychological tests. After 10 weeks the patient achieved a partial symptomatic improvement in mood, anxiety and quality of sleep, but his activity remained insufficient. We also observed an improvement in the parameters of cognitive functioning and quality of life. There was neither significant mood variations during the memantine use nor mood changes after its termination. No significant side effects were noted during the memantine treatment. We conclude that using memantine in bipolar depression may improve mood, cognitive functioning and quality of life. PMID:24474993

  3. Significant progression of load on the musculoskeletal system with extremely high loads, with rapid weekly weight gains, using the Anatoly Gravitational System, in a 10-week training period

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    Burke DT

    2013-10-01

    Full Text Available David T Burke,1 David Tran,1 Di Cui,1 Daniel P Burke,2 Samir Al-Adawi,3 Atsu SS Dorvlo41Emory University Medical School, Atlanta, GA, USA; 2Georgia College and State University, GA, USA; 3Department of Behavioral Medicine, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Oman; 4Department of Mathematics and Statistics, College of Science, Sultan Qaboos University, Muscat, OmanAbstract: In an age of increasing numbers of lifestyle diseases and plasticity of longevity, exercise and weight training have been increasingly recognized as both preventing and mitigating the severity of many illnesses. This study was designed to determine whether significant weight-lifting gains could be realized through the Anatoly Gravitational System. Specifically, this study sought to determine whether this once-weekly weight-training system could result in significant weekly strength gains during a 10-week training period. A total of 50 participants, ranging in age from 17 to 67 years, completed at least 10 weekly 30-minute training sessions. The results suggest participants could, on average, double their weight-lifting capacity within 10 sessions. This preliminary study, which would require further scrutiny, suggests the Anatoly Gravitational System provides a rather unique opportunity to load the musculoskeletal system with extremely high loads, with rapid weekly weight gains, using only short weekly training sessions. More studies are warranted to scrutinize these findings.Keywords: Anatoly Gravitational System, weight training, musculoskeletal system

  4. Augmentation of antipsychotics with glycine may ameliorate depressive and extrapyramidal symptoms in schizophrenic patients – a preliminary 10-week open-label study

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    Strzelecki, Dominik

    2013-07-01

    Full Text Available Aim. The objective of this study was to analyze the changes in depressive and extrapyramidal symptomatology during glycine augmentation of antipsychotic treatment in patients with schizophrenia.Materials and methods. Twenty-nine schizophrenic patients (ICD-10 with predominant negative symptoms in stable mental state participated in a 10-week open-label prospective study. Patients received stable doses of antipsychotic drugs for at least 3 months before glycine application. During the next 6 weeks patients received augmentation of antipsychotic treatment with glycine (up to 60 g per day. The first and last two weeks of observation were used to assess stability of mental state. Symptom severity was assessed using the Hamilton Depression Rating Scale (HDRS, the Positive and Negative Syndrome Scale (PANSS, and the Simpson-Angus Extrapyramidal Symptom Rating Scale (SASResults. In the studied group after 6 weeks of administration of glycine a significant improvement in depressive symptoms (reduced scores by 25.8% in HDRS, p <0.001 and reduced scoring in mood symptoms of PANSS were observed. In SAS a reduction of extrapyramidal symptoms’ severity (p <0.05 was also noted. Two weeks after the glycine augmentation the symptom severity in the HDRS, PANSS, and SAS remained at similar levels.Conclusions. Glycine augmentation of antipsychotic treatment may reduce the severity of depressive and extrapyramidal symptoms. Glycine use was safe and well tolerated.

  5. Change in proportional protein intake in a 10-week energy-restricted low- or high-fat diet, in relation to changes in body size and metabolic factors

    DEFF Research Database (Denmark)

    Stocks, Tanja; Taylor, Moira A; Ängquist, Lars;

    2013-01-01

    Objective: To investigate in a secondary analysis of a randomised trial the effects of a low-/high-fat diet and reported change from baseline in energy% from protein (prot%), in relation to changes in body size and metabolic factors. Methods: Obese adults (n = 771) were randomised to a 600 kcal e...... increased the percentage energy intake from protein showed the greatest reduction in weight and cholesterol, and a triglyceride reduction equally large to that of participants on a high-fat diet. Copyright © 2013 S. Karger GmbH, Freiburg.......Objective: To investigate in a secondary analysis of a randomised trial the effects of a low-/high-fat diet and reported change from baseline in energy% from protein (prot%), in relation to changes in body size and metabolic factors. Methods: Obese adults (n = 771) were randomised to a 600 kcal...... energy-deficient low-fat (20-25 fat%) or high-fat (40-45 fat%) diet over 10 weeks. Dietary intake data at baseline and during the intervention were available in 585 completers. We used linear regression to calculate the combined effects of randomised group and groups of prot% change (2) on outcomes...

  6. Place-based research project design for 10-week REU and two-week "mini-REU" internships using lake sediment cores

    Science.gov (United States)

    Myrbo, A.; Howes, T.; Thompson, R.; Drake, C.; Woods, P.; Schuldt, N.; Borkholder, B.; Marty, J.; Lafrancois, T.; Pellerin, H.

    2012-12-01

    . The two-week "mini-REU" was designed to attract students with little or no independent research experience, who might be intimidated by applying for a ten-week internship away from home (but who might apply for one after completing a good mini-REU). The arc of research, from site selection to field work and lab work to data interpretation and poster presentation, must be encompassed in these brief projects, so group projects with clear goals are best suited for mini-REUs. The May 2012 project, with twelve students in four research proxy groups (charcoal, phytoliths, plant macrofossils, and zooplankton), demonstrated that a FDL lake, Rice Portage, had extensive wild rice habitat prior to early 20th-century Euroamerican ditching; this proof was required in order for FDL to gain a permit from the Army Corps of Engineers to raise the lake level as part of a wild rice restoration effort. Each proxy group had one research advisor (a graduate student or soft money researcher), plus one UMN über-advisor for the project as a whole, as well as the Fond du Lac resource manager. All of these advisors also work with the 10-week interns throughout the summer.

  7. Experimental infection with the Paderborn isolate of classical swine fever virus in 10-week-old pigs: determination of viral replication kinetics by quantitative RT-PCR, virus isolation and antigen ELISA

    DEFF Research Database (Denmark)

    Uttenthal, Åse; Storgaard, Torben; Oleksiewicz, M.B.;

    2003-01-01

    We performed experimental infection in 10-week-old pigs with the Paderborn isolate of classical swine fever virus (CSFV). Despite being epidemiologically linked to the major CSFV outbreak in The Netherlands in 1997, the in vivo replication kinetics of this isolate have to our knowledge not been...

  8. The Impact of 10 weeks of Aerobic Exercise and Supplementation of Green Tea on Lipid Profile, Insulin Resistance and Liver Enzymes (GGT, ALT, AST) in Obese Diabetic Women (type 2)

    OpenAIRE

    M Izadi Ghahfarokhi; M Mogharnasi; M Faramarzi

    2015-01-01

    Background & aim: Physical training accompanied with herbal supplement consumption is one of the proposed methods for controlling obesity and its complications, such as diabetes, insulin resistance and inflammation of the liver. The purpose of this study was to evaluate the effect of 10 weeks of aerobic exercise and supplementation of green tea on lipid profile, insulin resistance and liver enzymes (GGT, ALT, AST) in obese diabetic women (type 2). Materials and Methods: A total of 46 di...

  9. An Investigation of Measuring Apparatus for Vo_2 During Exercise,and Effects of 10-week Exercise Training on Aerobic Work Capacity,Body Composition and Oxidative Enzymes in Skeletal Muscle in Obese-Diabetic Model OLETF Rats

    OpenAIRE

    Suzuki, Masato; Seino, Tetsuya; Kimura, Masaki; Hodumi, Noriko; Terada, Shin; Higuchi, Mitsuru; Shibasaki, Toshiaki

    2005-01-01

    SUZUKI, M., SEINO, T., KIMURA, M., HODUMI, N., TERADA, S., HIGUCHI, M., and SHIBASAKI, T. An Investigation of Measuring Appatratus for VO2 During Exercise, and Effects of 10-week Exercise Training on Aerobic Work Capacity, Body Composition and Oxidative Enzymes in Skeletal Muscle in Obese-Diabetic Model OLETF Rats. Abv. Exerc. Sports Physiol., Vol.11, No.1 pp.21-31, 2005. This study was conducted to develop an open-cicuit metabolic apparatus equipped with a treadmill for obese-diabetic model ...

  10. Comportamento da flexibilidade após 10 semanas de treinamento com pesos Comportamiento de la flexibilidad después de 10 semanas de entrenamiento con pesos Flexibility behavior after 10 weeks of resistance training

    Directory of Open Access Journals (Sweden)

    Edilson Serpeloni Cyrino

    2004-08-01

    flexibilidad. ANOVA y ANCOVA para medidas repetidas, seguidas por el test post hoc de Tukey, cuando P The objective of this study was to analyze the flexibility behavior of different articulations after 10 weeks of resistance training (RT. That is why, 16 inactive men (23.0 ± 2.1 years; 68.0 ± 7.0 kg; 178.8 ± 8.7 cm apparently healthy were randomly divided into training group (TG, n = 8 and control group (CG, n = 8. The group TG was submitted to 10 consecutive weeks of RT (three weekly sessions in alternated days, whereas for group CG, no systematized program of physical activities was developed in this period. The 11 exercised that composed the RT program were performed in three series of 8-12 RM. The shoulder flexion and extension, trunk flexion, lateral flexion and extension, hip extension and flexion, elbow extension and flexion and knee flexion were used for the analysis of the flexibility behavior. The ANOVA and ANCOVA for repeated measures, followed by the Tukey post hoc test for P < 0.05 were used for data treatment. Significant increase on flexibility between pre and post experiment were found in TG in shoulder flexion movements (right hemisphere, P < 0.05, hip extension (left hemisphere, P < 0.05, trunk extension (P < 0.05, trunk flexion (P < 0.05 and trunk lateral flexion (right hemisphere, P < 0.05; left hemisphere, P < 0.01. Although, the effect of the interaction group vs time was only identified in elbow flexion movements (right and left hemisphere, P < 0.05, hip extension (left hemisphere, P < 0.05 and trunk lateral flexion (left hemisphere, P < 0.01. Thus, the results of the present study suggest that the 10 first weeks of RT practice may contribute effectively for the maintenance or improvement of the flexibility levels observed in the pre-training period, in different articulations.

  11. Randomization tests

    CERN Document Server

    Edgington, Eugene

    2007-01-01

    Statistical Tests That Do Not Require Random Sampling Randomization Tests Numerical Examples Randomization Tests and Nonrandom Samples The Prevalence of Nonrandom Samples in Experiments The Irrelevance of Random Samples for the Typical Experiment Generalizing from Nonrandom Samples Intelligibility Respect for the Validity of Randomization Tests Versatility Practicality Precursors of Randomization Tests Other Applications of Permutation Tests Questions and Exercises Notes References Randomized Experiments Unique Benefits of Experiments Experimentation without Mani

  12. Random Walks on Random Graphs

    Science.gov (United States)

    Cooper, Colin; Frieze, Alan

    The aim of this article is to discuss some of the notions and applications of random walks on finite graphs, especially as they apply to random graphs. In this section we give some basic definitions, in Section 2 we review applications of random walks in computer science, and in Section 3 we focus on walks in random graphs.

  13. 5~10周龄扬州鹅日粮中适宜蛋氨酸水平的研究%Study on Optimum Dietary Methionine Levels of 5~10 Week Old Yangzhou Gosling

    Institute of Scientific and Technical Information of China (English)

    周秋燕; 王志跃; 杨海明; 施寿荣; 张康宁; 韩厚明

    2008-01-01

    A dose-response experiment with different dietary levels of methioninewas conducted to estimate opti-mum dietary methionine level for 5~10 week-old Yangzhou gosling. One hundred and fifty 2S-day-old Yangzhou goslings were divided into 15 pens with 10 birds per pen according to similar pen weight. There were 5 dietary treat-ments, each containing 3 replicate pens. Five levels of dietary methionine (Met) were 0.23%, 0.33%, 0.43%, 0.53% and 0.63%. The results were as follows: there were significant difference among groups in growth performance,carcass characteristics and serum parameters (P<0.05). The feed/gain of goslings fed 0.43% Met was lower than those fed 0.23% Met (P<0.05). Goslings fed 0.43% and 0.53% Met were higher than other treatments on the items of slaughter percentage, semi-eviscerated percentage, eviscerated percentage, breast meat percentage and leg muscle percentage, and abdominal fat percentage of goslings fed 0.53% and 0.63% Met were lower than goslings fed 0.23% Met (P<0.05). Content of BUN of goslings fed 0.43% and 0.53% Met were lower than goslings fed 0.23% Met (P<0.05), and content of TP of goslings fed 0.53% Met were higher than goslings fed 0.23% Met (P<0.05). According to the results, when the dietary protein level was 15.82% the optimal Met requirement of Yangzhou goslings of 5~10 weeks was 0.43%~0.53%.%本文旨在研究5~10周龄扬州鹅日粮中适宜的蛋氨酸水平.选用28日龄的健康扬州鹅150只,随机分成5组,每组3个重复,每个重复10只,公母各半.试验采用单因子有重复设计,日粮蛋氨酸水平分别为0.23%、0.33%、0.43%、0.53%和0.63%.结果表明:日粮不同蛋氨酸水平对5~10周龄扬州鹅生长性能、屠宰性能和血清生化指标均存在显著影响.(1)0.43%蛋氨酸水平试验组鹅的生长速度最快,料重比显著低于0.23%组(P<0.05);(2)0.43%和0.53%蛋氨酸水平试验组鹅在屠宰率、半净膛率、全净膛率、胸肌率和腿肌

  14. Random duality

    Institute of Scientific and Technical Information of China (English)

    GUO TieXin; CHEN XinXiang

    2009-01-01

    The purpose of this paper is to provide a random duality theory for the further development of the theory of random conjugate spaces for random normed modules.First,the complicated stratification structure of a module over the algebra L(μ,K) frequently makes our investigations into random duality theory considerably different from the corresponding ones into classical duality theory,thus in this paper we have to first begin in overcoming several substantial obstacles to the study of stratification structure on random locally convex modules.Then,we give the representation theorem of weakly continuous canonical module homomorphisms,the theorem of existence of random Mackey structure,and the random bipolar theorem with respect to a regular random duality pair together with some important random compatible invariants.

  15. Random duality

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    The purpose of this paper is to provide a random duality theory for the further development of the theory of random conjugate spaces for random normed modules. First, the complicated stratification structure of a module over the algebra L(μ, K) frequently makes our investigations into random duality theory considerably difierent from the corresponding ones into classical duality theory, thus in this paper we have to first begin in overcoming several substantial obstacles to the study of stratification structure on random locally convex modules. Then, we give the representation theorem of weakly continuous canonical module homomorphisms, the theorem of existence of random Mackey structure, and the random bipolar theorem with respect to a regular random duality pair together with some important random compatible invariants.

  16. 10周有氧训练对心力衰竭大鼠心脏重塑和运动耐力的影响%Effects of 10 -week aerobic exercise on cadiac remodeling and exercise tolerance of heart failure rats

    Institute of Scientific and Technical Information of China (English)

    程蕾; 李晓霞

    2015-01-01

    was established through ligating coronary artery in clean grade Wistar rats of 8 weeks.After 4 weeks,laboratory animals were randomly divided into sham operation con-trol group (Sham),sham operation plus exercise group (Sham +E),heart failure control group (HF)and heart failure plus exercise group (HF +E).Rats in Sham +E group and HF +E group performed aerobic treadmill exercise of 10 weeks while those of Sham group and HF group main-tained resting state.Before and after the experiment,cardiac structure parameters including left ven-tricular internal diameter at diastole (LVIDd ), left ventricular internal diameter at systole (LVIDs),left ventricular anterior wall diameter at diastole (LVAWDd),left ventricular anterior wall diameter at systole (LVAWDs),left ventricular posterior wall diameter at diastole (LVPWDd) and left ventricular posterior wall diameter at systole (LVPWDs),cardiac function parameters inclu-ding fractional shortening (FS),left ventricular ejection fraction (LVEF)and heart rate (HR) were detected by ultrechocardiograph;exercise tolerance parameters including exhaust time,exhaust distance and maximal speed were tested by incremental treadmill test.After test,heart tissue was collected for weighting body weight (BW),left ventricular weight (LVW),right ventricular weight (RVW)and left ventricular mass index (LVMI),histopathology study and collagen volume fraction (CVF)by Masson staining.Results:1 )Compared with Sham group,exhaust time,exhaust dis-tance,maximal speed,BW,LVIDd,FS and LVEF reduced (P <0.01 )while LVW,LVMI, LVAWDd,LVAWDs,LVPWDd,LVPWDs and CVF raised (P <0.01)in HF group;2)Compared with HF group,exhaust time,exhaust distance,maximal speed,LVW,LVMI,LVIDd,FS and LVEF increased (P <0.01)while HR and CVF decreased (P <0.01)in HF +E group.Conclu-sion:1)HF resulted in cardiac structure and function remodeling and reduced exercise capacity;2) Aerobic treadmill training of 10 weeks reversed cardiac remodeling of heart failure rats,thus enhan

  17. Energy randomness

    OpenAIRE

    Miller, Joseph S.; Rute, Jason

    2015-01-01

    Energy randomness is a notion of partial randomness introduced by Diamondstone and Kjos-Hanssen to characterize the sequences that can be elements of a Martin-L\\"of random closed set (in the sense of Barmpalias, Brodhead, Cenzer, Dashti, and Weber). It has also been applied by Allen, Bienvenu, and Slaman to the characterization of the possible zero times of a Martin-L\\"of random Brownian motion. In this paper, we show that $X \\in 2^\\omega$ is $s$-energy random if and only if $\\sum_{n\\in\\omega...

  18. Randomized random walk on a random walk

    International Nuclear Information System (INIS)

    This paper discusses generalizations of the model introduced by Kehr and Kunter of the random walk of a particle on a one-dimensional chain which in turn has been constructed by a random walk procedure. The superimposed random walk is randomised in time according to the occurrences of a stochastic point process. The probability of finding the particle in a particular position at a certain instant is obtained explicitly in the transform domain. It is found that the asymptotic behaviour for large time of the mean-square displacement of the particle depends critically on the assumed structure of the basic random walk, giving a diffusion-like term for an asymmetric walk or a square root law if the walk is symmetric. Many results are obtained in closed form for the Poisson process case, and these agree with those given previously by Kehr and Kunter. (author)

  19. 10周游泳运动对高血压大鼠血浆一氧化氮、血管性血友病因子、P-选择素含量的影响%Effects of 10-week swimming exercise on plasma nitric oxide, von Willebrand factor and P-selectin production in spontaneous hypertension rats

    Institute of Scientific and Technical Information of China (English)

    陈华卫; 窦丽; 张钧

    2012-01-01

    Objective: To investigate the effects of exercise on endothelium function and platelet activity in spontaneous hypertension rats (SHR). Method: Seventeen male SHR were divided into 2 groups randomly, control group (8 SHR) and exercise group (9 SHR). In exercise group SHR performed swimming exercise (5 times/week) at moderate intensity (60min/time) for 10 weeks. Resting blood pressure was measured fortnightly during exercise training period. After the exercise period, plasma nitric oxide (NO), platelet-derived NO level and plasma von Willebrand factor (vWF), P-selectin production were defected. Result: Compared with control group, SHR resting blood pressure decreased significantly, plasma NO level and platelet NO level increased significantly, while plasma vWF and P-selectin production decreased in exercise group-Conclusion: This study implies that long-term regular aerobic exercise can inhibit resting blood pressure gently and continuously in SHR, and can improve endothelium function and platelet activity significantly in hypertension, which can control the occurrence of thrombosis complicated in hypertension.%目的:研究运动对自发性高血压大鼠内皮功能、血小板活化状态的影响.方法:10周龄,雄性自发性高血压大鼠(SHR) 17只,随机分为对照组(8只)和运动组(9只).运动组SHR进行为期10周,每周5次,每次60min的游泳运动训练.实验期间每两周测定SHR血压,10周运动后,测定血浆一氧化氮(NO)水平,血小板NO水平,血管性血友病因子(vWF)、P-选择素浓度的变化.结果:运动组大鼠血压较对照组显著下降,血浆和血小板NO水平显著上升,血浆vWF和p-选择素显著降低.结论:规则有氧运动能产生较平稳持续的降压效果,能明显改善高血压内皮功能和血小板活化状态,降低高血压血栓并发症的发生.

  20. Promoting First Relationships: Randomized Trial of a Relationship-Based Intervention for Toddlers in Child Welfare

    OpenAIRE

    Spieker, Susan J.; Oxford, Monica L.; Kelly, Jean F.; Nelson, Elizabeth M.; Fleming, Charles B.

    2012-01-01

    We conducted a community based, randomized control trial of Promoting First Relationships (PFR; Kelly, Sandoval, Zuckerman, & Buehlman, 2008) to improve parenting and toddler outcomes for toddlers in state dependency. Toddlers (10 – 24 months; N = 210) with a recent placement disruption were randomized to 10-week PFR or a comparison condition. Community agency providers were trained to use PFR in the intervention for caregivers. From baseline to post-intervention follow-up, observational rati...

  1. Random Matrices

    CERN Document Server

    Stephanov, M A; Wettig, T

    2005-01-01

    We review elementary properties of random matrices and discuss widely used mathematical methods for both hermitian and nonhermitian random matrix ensembles. Applications to a wide range of physics problems are summarized. This paper originally appeared as an article in the Wiley Encyclopedia of Electrical and Electronics Engineering.

  2. Effects of Dietary Crude Protein and Metabolizable Energy Levels on Performance and Nitrogen Balance of Sichuan White Geese Aged from 9 to 10 Weeks%饲粮粗蛋白质和代谢能水平对9~10周龄四川白鹅生产性能和氮平衡的影响

    Institute of Scientific and Technical Information of China (English)

    李琴; 陈明君; 彭祥伟

    2015-01-01

    This experiment was conducted to study the effects of crude protein ( CP) and metabolizable energy ( ME) levels on performance and nitrogen balance of Sichuan white geese aged from 9 to 10 weeks. Four hun-dred and thirty two 57-day-old healthy Sichuan white geese with similar body weight were used in a 3×3 double factorial design trial and randomly allocated into 9 groups with 4 replicates in each group and 12 geese in each replicate. The geese were fed 9 experimental diets with three levels of ME (12.86, 12.13 and 11.43 MJ/kg) and three levels of CP ( 15%, 13% or 11%) . The feeding experiment lasted for 14 days. Eight geese per group were picked up on the basis of individual weight immediate to the average weight of every group on day 8 of the experiment, and the geese were used in a metabolism trial. The results showed as follows:1) CP level had significant effects on daily dry matter ( DM) intake and feed to gain ratio ( P<0.05) , the daily DM intake and feed to gain ratio were decreased with CP level increased; ME level had significant effect on daily DM intake ( P<0.01) , the daily DM intake was decreased with ME level increased; the interaction between CP and ME levels had significant effect on the consumed CP and ME for gain per gram (P<0.05 or P<0.01), with CP level increased, the consumed CP for gain per gram was increased, the consumed ME for gain per gram was decreased. 2) CP level had significant effects on nitrogen intake, nitrogen excretion from excrement, deposited nitrogen, GE excretion from excrement and availability of GE ( P<0.05 or P<0.01) , the nitrogen intake, ni-trogen excretion from excrement, deposited nitrogen, GE excretion from excrement were increased with CP level increased. The interaction between dietary CP and ME levels had significant effects on deposited nitrogen and availability of nitrogen (P<0.05). The results suggest that for Sichuan white geese aged from 9 to 10 weeks, the suitable dietary levels of CP and ME are 13% and 11

  3. Random magnetism

    International Nuclear Information System (INIS)

    The 'ingredients' which control a phase transition in well defined systems as well as in random ones (e.q. random magnetic systems) are listed and discussed within a somehow unifying perspective. Among these 'ingredients' the couplings and elements responsible for the cooperative phenomenon, the topological connectivity as well as possible topological incompatibilities, the influence of new degrees of freedom, the order parameter dimensionality, the ground state degeneracy and finally the 'quanticity' of the system are found. The general trends, though illustrated in magnetic systems, essentially hold for all phase transitions, and give a basis for connection of this area with Field theory, Theory of dynamical systems, etc. (Author)

  4. Random dynamics

    International Nuclear Information System (INIS)

    The goal of random dynamics is the derivation of the laws of Nature as we know them (standard model) from inessential assumptions. The inessential assumptions made here are expressed as sets of general models at extremely high energies: gauge glass and spacetime foam. Both sets of models lead tentatively to the standard model. (orig.)

  5. Randomized metarounding

    Energy Technology Data Exchange (ETDEWEB)

    CARR,ROBERT D.; VEMPALA,SANTOSH

    2000-01-25

    The authors present a new technique for the design of approximation algorithms that can be viewed as a generalization of randomized rounding. They derive new or improved approximation guarantees for a class of generalized congestion problems such as multicast congestion, multiple TSP etc. Their main mathematical tool is a structural decomposition theorem related to the integrality gap of a relaxation.

  6. Random Decrement

    DEFF Research Database (Denmark)

    Asmussen, J.C.; Ibrahim, S.R.; Brincker, Rune

    Abstraet Thispaper demansirates how to use the Random Decrement (RD) technique for identification o flinear structures subjected to ambient excitation. The theory behind the technique will be presented and guidelines how to choose the different variables will be given. This is done by introducing a...

  7. Random Decrement

    DEFF Research Database (Denmark)

    Asmussen, J. C.; Ibrahim, S. R.; Brincker, Rune

    This paper demonstrates how to use the Random Decrement (RD) technique for identification of linear structures subjected to ambient excitation. The theory behind the technique will be presented and guidelines how to choose the different variables will be given. This is done by introducing a new...

  8. Random Decrement

    DEFF Research Database (Denmark)

    Asmussen, J. C.; Ibrahim, R.; Brincker, Rune

    1998-01-01

    This paper demonstrates how to use the Random Decrement (RD) technique for identification of linear structures subjected to ambient excitation. The theory behind the technique will be presented and guidelines how to choose the different variables will be given. This is done by introducing a new...

  9. Permanency Outcomes for Toddlers in Child Welfare Two Years After a Randomized Trial of a Parenting Intervention

    OpenAIRE

    Spieker, Susan J.; Oxford, Monica L.; Fleming, Charles B.

    2014-01-01

    This study reports on child welfare outcomes of a community based, randomized control trial of Promoting First Relationships® (PFR; Kelly, Sandoval, Zuckerman, & Buehlman, 2008), a 10-week relationship-based home visiting program, on stability of children’s placements and permanency status two years after enrollment into the study. Toddlers 10 – 24 months (N = 210) with a recent placement disruption were randomized, along with their birth or foster/kin parents, to PFR (n = 105) or a compariso...

  10. 9~10周龄中畜小型白羽肉鸭公鸭粗蛋白质和代谢能需要量的研究%Requirements of Crude Protein and Metabolizable Energy of Male China Micro-Duck Aged from 9 to 10 Weeks

    Institute of Scientific and Technical Information of China (English)

    汪水平; 彭祥伟; 解华东

    2013-01-01

    本试验旨在研究9~10周龄中畜小型白羽肉鸭(CMD)公鸭粗蛋白质(CP)和代谢能(ME)的需要量.采用3×3双因素试验设计,设3个CP水平(18%、16%、14%)和3个ME水平(12.92、12.19、11.49 MJ/kg),配制9种试验饲粮.选择540只体重相近、健康的54日龄CMD公鸭,随机分为9组,每组4个重复,每个重复15只.每组随机饲喂1种试验饲粮.饲养试验的试验期为17 d,其中第1~3天为预试期,第4~17天为正试期.在试验期第11天,每组挑选10只体重接近各组平均体重的试验鸭,进行代谢试验.在试验期第4天07:00饲喂前,从每组中挑选9只体重接近平均体重的试验鸭屠宰,进行比较屠宰试验.结果表明:饲粮CP水平显著(P<0.05)或极显著(P<0.01)影响日增重和料重比,而饲粮ME水平极显著影响日干物质进食量(P<0.01);饲粮CP和ME水平的互作极显著影响生长性能(P<0.01);饲粮ME水平极显著影响总能利用率(P<0.01);饲粮CP和ME水平的互作显著影响氮利用率和总能利用率(P<0.05);饲粮CP和ME水平及其互作显著(P<0.05)或极显著(P<0.01)影响CP沉积率和ME沉积率.结果提示:9~10周龄CMD公鸭CP和ME日维持需要量分别为13.279 g/kg W0.75和1 000.969 kJ/kg W0.75,CP和ME需要量计算公式分别为CP=13.279W0.75 +0.019△W和ME=1 000.969W0.75+1.083△W(W0.75为代谢体重,△W为日增重),饲粮CP和ME水平分别为16.16%和12.15 MJ/kg.%This experiment was conducted to study the requirements of crude protein (CP) and metabolizable energy (ME) of China micro-duck (CMD) male ducks aged from 9 to 10 weeks.Five hundred and forty healthy 54-day-old male CMD ducks with similar body weight were used in a 3 × 3 double factorial design trial and randomly allocated into 9 groups with 4 replicates in each group and 15 ducks in each replicate.The ducks were fed 9 experimental diets with three levels of CP (18%,16% or 14%) and ME (12.92,12.19 or 11.49 MJ/kg).The feeding

  11. RANDOM LASSO.

    Science.gov (United States)

    Wang, Sijian; Nan, Bin; Rosset, Saharon; Zhu, Ji

    2011-03-01

    We propose a computationally intensive method, the random lasso method, for variable selection in linear models. The method consists of two major steps. In step 1, the lasso method is applied to many bootstrap samples, each using a set of randomly selected covariates. A measure of importance is yielded from this step for each covariate. In step 2, a similar procedure to the first step is implemented with the exception that for each bootstrap sample, a subset of covariates is randomly selected with unequal selection probabilities determined by the covariates' importance. Adaptive lasso may be used in the second step with weights determined by the importance measures. The final set of covariates and their coefficients are determined by averaging bootstrap results obtained from step 2. The proposed method alleviates some of the limitations of lasso, elastic-net and related methods noted especially in the context of microarray data analysis: it tends to remove highly correlated variables altogether or select them all, and maintains maximal flexibility in estimating their coefficients, particularly with different signs; the number of selected variables is no longer limited by the sample size; and the resulting prediction accuracy is competitive or superior compared to the alternatives. We illustrate the proposed method by extensive simulation studies. The proposed method is also applied to a Glioblastoma microarray data analysis. PMID:22997542

  12. Fractional randomness

    Science.gov (United States)

    Tapiero, Charles S.; Vallois, Pierre

    2016-11-01

    The premise of this paper is that a fractional probability distribution is based on fractional operators and the fractional (Hurst) index used that alters the classical setting of random variables. For example, a random variable defined by its density function might not have a fractional density function defined in its conventional sense. Practically, it implies that a distribution's granularity defined by a fractional kernel may have properties that differ due to the fractional index used and the fractional calculus applied to define it. The purpose of this paper is to consider an application of fractional calculus to define the fractional density function of a random variable. In addition, we provide and prove a number of results, defining the functional forms of these distributions as well as their existence. In particular, we define fractional probability distributions for increasing and decreasing functions that are right continuous. Examples are used to motivate the usefulness of a statistical approach to fractional calculus and its application to economic and financial problems. In conclusion, this paper is a preliminary attempt to construct statistical fractional models. Due to the breadth and the extent of such problems, this paper may be considered as an initial attempt to do so.

  13. Quetiapine Augments the Effect of Citalopram in Non-Refractory Obsessive-Compulsive Disorder: A Randomized, Double-Blind, Placebo-Controlled Study of 76 Patients

    NARCIS (Netherlands)

    N.C.C. Vulink; D. Denys; S.B.A.H.A. Fluitman; J.C.M. Meinardi; H.G.M. Westenberg

    2009-01-01

    Objective: To assess the efficacy of quetiapine addition to citalopram in treatment-naive or medication-free obsessive-compulsive disorder (OCD) patients. Method. Seventy-six patients who met DSM-IV criteria for OCD and who were drug-free or drug-naive at entry were randomly assigned in a 10-week, d

  14. Paroxetine Treatment in Children and Adolescents with Obsessive-Compulsive Disorder: A Randomized, Multicenter, Double-Blind, Placebo-Controlled Trial

    Science.gov (United States)

    Geller, Daniel A.; Wagner, Karen Dineen; Emslie, Graham; Murphy, Tanya; Carpenter, David J.; Wetherhold, Erica; Perera, Phil; Machin, Andrea; Gardiner, Christel

    2004-01-01

    Objective: To assess the efficacy and safety of paroxetine for the treatment of pediatric obsessive-compulsive disorder.Method: Children (7-11 years of age) and adolescents (12-17 years of age) meeting DSM-IV criteria for obsessive-compulsive disorder were randomized to paroxetine (10-50 mg/day) or placebo for 10 weeks. The primary efficacy…

  15. Random tensors

    CERN Document Server

    Gurau, Razvan

    2017-01-01

    Written by the creator of the modern theory of random tensors, this book is the first self-contained introductory text to this rapidly developing theory. Starting from notions familiar to the average researcher or PhD student in mathematical or theoretical physics, the book presents in detail the theory and its applications to physics. The recent detections of the Higgs boson at the LHC and gravitational waves at LIGO mark new milestones in Physics confirming long standing predictions of Quantum Field Theory and General Relativity. These two experimental results only reinforce today the need to find an underlying common framework of the two: the elusive theory of Quantum Gravity. Over the past thirty years, several alternatives have been proposed as theories of Quantum Gravity, chief among them String Theory. While these theories are yet to be tested experimentally, key lessons have already been learned. Whatever the theory of Quantum Gravity may be, it must incorporate random geometry in one form or another....

  16. Random functions and turbulence

    CERN Document Server

    Panchev, S

    1971-01-01

    International Series of Monographs in Natural Philosophy, Volume 32: Random Functions and Turbulence focuses on the use of random functions as mathematical methods. The manuscript first offers information on the elements of the theory of random functions. Topics include determination of statistical moments by characteristic functions; functional transformations of random variables; multidimensional random variables with spherical symmetry; and random variables and distribution functions. The book then discusses random processes and random fields, including stationarity and ergodicity of random

  17. Random fixed points and random differential inclusions

    Directory of Open Access Journals (Sweden)

    Nikolaos S. Papageorgiou

    1988-01-01

    Full Text Available In this paper, first, we study random best approximations to random sets, using fixed point techniques, obtaining this way stochastic analogues of earlier deterministic results by Browder-Petryshyn, KyFan and Reich. Then we prove two fixed point theorems for random multifunctions with stochastic domain that satisfy certain tangential conditions. Finally we consider a random differential inclusion with upper semicontinuous orientor field and establish the existence of random solutions.

  18. Topics in random walks in random environment

    International Nuclear Information System (INIS)

    Over the last twenty-five years random motions in random media have been intensively investigated and some new general methods and paradigms have by now emerged. Random walks in random environment constitute one of the canonical models of the field. However in dimension bigger than one they are still poorly understood and many of the basic issues remain to this day unresolved. The present series of lectures attempt to give an account of the progresses which have been made over the last few years, especially in the study of multi-dimensional random walks in random environment with ballistic behavior. (author)

  19. A Chinese Chan-Based Mind-Body Intervention Improves Sleep on Patients with Depression: A Randomized Controlled Trial

    OpenAIRE

    Chan, Agnes S.; Wong, Queenie Y.; Sophia L. Sze; Kwong, Patrick P. K.; Yvonne M. Y. Han; Mei-chun Cheung

    2012-01-01

    Sleep disturbance is a common problem associated with depression, and cognitive-behavioral therapy (CBT) is a more common behavioral intervention for sleep problems. The present study compares the effect of a newly developed Chinese Chan-based intervention, namely Dejian mind-body intervention (DMBI), with the CBT on improving sleep problems of patients with depression. Seventy-five participants diagnosed with major depressive disorder were randomly assigned to receive 10 weekly sessions of C...

  20. Comparison of oral psoralen-UV-A with a portable tanning unit at home vs hospital-administered bath psoralen-UV-A in patients with chronic hand eczema - An open-label randomized controlled trial of efficacy

    NARCIS (Netherlands)

    van Coevorden, AM; Kamphof, WG; van Sonderen, E; Bruynzeel, DP; Coenraads, PJ

    2004-01-01

    Objective: To study whether oral psoralen-UV-A (PUVA) with a portable tanning unit at home is as effective as hospital-administered bath PUVA in patients with chronic hand eczema. Design: Open-label randomized controlled trial, with a 10-week treatment period and an 8-week follow-up period. Setting:

  1. Completely random signed measures

    DEFF Research Database (Denmark)

    Hellmund, Gunnar

    Completely random signed measures are defined, characterized and related to Lévy random measures and Lévy bases.......Completely random signed measures are defined, characterized and related to Lévy random measures and Lévy bases....

  2. Effect of brief daily exercise on headache among adults--secondary analysis of a randomized controlled trial

    DEFF Research Database (Denmark)

    Andersen, Lars L; Mortensen, Ole S; Zebis, Mette K;

    2011-01-01

    OBJECTIVE: This paper investigates secondary outcomes (headache) in a randomized controlled trial with physical exercise among office workers with neck/shoulder pain. METHODS: A total of 198 office workers with frequent neck/shoulder pain were randomly allocated to either one of two intervention...... groups (10 weeks of resistance training with elastic tubing for 2 or 12 minutes per day, 5 times a week) or the control group, which received weekly health information. Secondary outcomes included changes in frequency, intensity, and duration of headache after ten weeks. RESULTS: Compared...... exercise programs stresses the applicability of our findings....

  3. Comparing MTI randomization procedures to blocked randomization.

    Science.gov (United States)

    Berger, Vance W; Bejleri, Klejda; Agnor, Rebecca

    2016-02-28

    Randomization is one of the cornerstones of the randomized clinical trial, and there is no shortage of methods one can use to randomize patients to treatment groups. When deciding which one to use, researchers must bear in mind that not all randomization procedures are equally adept at achieving the objective of randomization, namely, balanced treatment groups. One threat is chronological bias, and permuted blocks randomization does such a good job at controlling chronological bias that it has become the standard randomization procedure in clinical trials. But permuted blocks randomization is especially vulnerable to selection bias, so as a result, the maximum tolerated imbalance (MTI) procedures were proposed as better alternatives. In comparing the procedures, we have somewhat of a false controversy, in that actual practice goes uniformly one way (permuted blocks), whereas scientific arguments go uniformly the other way (MTI procedures). There is no argument in the literature to suggest that the permuted block design is better than or even as good as the MTI procedures, but this dearth is matched by an equivalent one regarding actual trials using the MTI procedures. So the 'controversy', if we are to call it that, pits misguided precedent against sound advice that tends to be ignored in practice. We shall review the issues to determine scientifically which of the procedures is better and, therefore, should be used. PMID:26337607

  4. Workplace strength training prevents deterioration of work ability among workers with chronic pain and work disability: a randomized controlled trial

    DEFF Research Database (Denmark)

    Sundstrup, Emil; Jakobsen, Markus D; Brandt, Mikkel;

    2014-01-01

    to December 2012. The outcome measure was the change from baseline to 10-week follow-up in the work ability index (WAI). RESULTS: A priori hypothesis testing showed a group×time interaction for WAI (P...OBJECTIVE: Imbalance between work demands and individual resources can lead to musculoskeletal disorders and reduced work ability. The aim of this study was to evaluate the effect of two contrasting interventions on work ability among slaughterhouse workers with chronic pain and work disability....... METHODS: Sixty-six slaughterhouse workers with upper-limb chronic pain and work disability were randomly allocated to 10 weeks of either strength training for the shoulder, arm, and hand muscles (3 times per week, 10 minutes per session) or ergonomic training (usual care control group) from September...

  5. Psychological and cognitive outcomes of a randomized trial of exercise among patients with chronic obstructive pulmonary disease.

    Science.gov (United States)

    Emery, C F; Schein, R L; Hauck, E R; MacIntyre, N R

    1998-05-01

    Exercise rehabilitation is recommended increasingly for patients with chronic obstructive pulmonary disease (COPD). This study examined the effect of exercise and education on 79 older adults (M age = 66.6 +/- 6.5 years; 53% female) with COPD, randomly assigned to 10 weeks of (a) exercise, education, and stress management (EXESM; n = 29); (b) education and stress management (ESM; n = 25); or (c) waiting list (WL; n = 25). EXESM included 37 sessions of exercise, 16 educational lectures, and 10 weekly stress management classes. ESM included only the 16 lectures and 10 stress management classes. Before and after the intervention, assessments were conducted of physiological functioning (pulmonary function, exercise endurance), psychological well-being (depression, anxiety, quality of life), and cognitive functioning (attention, motor speed, mental efficiency, verbal processing). Repeated measures multivariate analysis of variance indicated that EXESM participants experienced changes not observed among ESM and WL participants, including improved endurance, reduced anxiety, and improved cognitive performance (verbal fluency). PMID:9619472

  6. Random walks on combs

    CERN Document Server

    Durhuus, B; Wheater, J; Durhuus, Bergfinnur; Jonsson, Thordur; Wheater, John

    2006-01-01

    We develop techniques to obtain rigorous bounds on the behaviour of random walks on combs. Using these bounds we calculate exactly the spectral dimension of random combs with infinite teeth at random positions or teeth with random but finite length. We also calculate exactly the spectral dimension of some fixed non-translationally invariant combs. We relate the spectral dimension to the critical exponent of the mass of the two-point function for random walks on random combs, and compute mean displacements as a function of walk duration. We prove that the mean first passage time is generally infinite for combs with anomalous spectral dimension.

  7. Matricially free random variables

    CERN Document Server

    Lenczewski, Romuald

    2008-01-01

    We show that the operatorial framework developed by Voiculescu for free random variables can be extended to arrays of random variables whose multiplication imitates matricial multiplication. The associated notion of independence, called matricial freeness, can be viewed as a generalization of both freeness and monotone independence. At the same time, the sums of matricially free random variables, called random pseudomatrices, are closely related to Gaussian random matrices. The main results presented in this paper concern the standard and tracial central limit theorems for random pseudomatrices and the corresponding limit distributions which can be viewed as matricial generalizations of semicirle laws.

  8. Design and methods of a social network isolation study for reducing respiratory infection transmission: The eX-FLU cluster randomized trial

    OpenAIRE

    Aiello, Allison E.; Simanek, Amanda M.; Marisa C Eisenberg; Alison R. Walsh; Brian Davis; Erik Volz; Caroline Cheng; Rainey, Jeanette J.; Amra Uzicanin; Hongjiang Gao; Nathaniel Osgood; Dylan Knowles; Kevin Stanley; Kara Tarter; Monto, Arnold S.

    2016-01-01

    Background: Social networks are increasingly recognized as important points of intervention, yet relatively few intervention studies of respiratory infection transmission have utilized a network design. Here we describe the design, methods, and social network structure of a randomized intervention for isolating respiratory infection cases in a university setting over a 10-week period. Methodology/principal findings: 590 students in six residence halls enrolled in the eX-FLU study during a ...

  9. On Gaussian random supergravity

    International Nuclear Information System (INIS)

    We study the distribution of metastable vacua and the likelihood of slow roll inflation in high dimensional random landscapes. We consider two examples of landscapes: a Gaussian random potential and an effective supergravity potential defined via a Gaussian random superpotential and a trivial Kähler potential. To examine these landscapes we introduce a random matrix model that describes the correlations between various derivatives and we propose an efficient algorithm that allows for a numerical study of high dimensional random fields. Using these novel tools, we find that the vast majority of metastable critical points in N dimensional random supergravities are either approximately supersymmetric with |F|≪Msusy or supersymmetric. Such approximately supersymmetric points are dynamical attractors in the landscape and the probability that a randomly chosen critical point is metastable scales as log (P)∝−N. We argue that random supergravities lead to potentially interesting inflationary dynamics

  10. Quantum Random Number Generators

    OpenAIRE

    Herrero-Collantes, Miguel; Garcia-Escartin, Juan Carlos

    2016-01-01

    Random numbers are a fundamental resource in science and engineering with important applications in simulation and cryptography. The inherent randomness at the core of quantum mechanics makes quantum systems a perfect source of entropy. Quantum random number generation is one of the most mature quantum technologies with many alternative generation methods. We discuss the different technologies in quantum random number generation from the early devices based on radioactive decay to the multipl...

  11. Blocked Randomization with Randomly Selected Block Sizes

    Directory of Open Access Journals (Sweden)

    Jimmy Efird

    2010-12-01

    Full Text Available When planning a randomized clinical trial, careful consideration must be given to how participants are selected for various arms of a study. Selection and accidental bias may occur when participants are not assigned to study groups with equal probability. A simple random allocation scheme is a process by which each participant has equal likelihood of being assigned to treatment versus referent groups. However, by chance an unequal number of individuals may be assigned to each arm of the study and thus decrease the power to detect statistically significant differences between groups. Block randomization is a commonly used technique in clinical trial design to reduce bias and achieve balance in the allocation of participants to treatment arms, especially when the sample size is small. This method increases the probability that each arm will contain an equal number of individuals by sequencing participant assignments by block. Yet still, the allocation process may be predictable, for example, when the investigator is not blind and the block size is fixed. This paper provides an overview of blocked randomization and illustrates how to avoid selection bias by using random block sizes.

  12. Blocked randomization with randomly selected block sizes.

    Science.gov (United States)

    Efird, Jimmy

    2011-01-01

    When planning a randomized clinical trial, careful consideration must be given to how participants are selected for various arms of a study. Selection and accidental bias may occur when participants are not assigned to study groups with equal probability. A simple random allocation scheme is a process by which each participant has equal likelihood of being assigned to treatment versus referent groups. However, by chance an unequal number of individuals may be assigned to each arm of the study and thus decrease the power to detect statistically significant differences between groups. Block randomization is a commonly used technique in clinical trial design to reduce bias and achieve balance in the allocation of participants to treatment arms, especially when the sample size is small. This method increases the probability that each arm will contain an equal number of individuals by sequencing participant assignments by block. Yet still, the allocation process may be predictable, for example, when the investigator is not blind and the block size is fixed. This paper provides an overview of blocked randomization and illustrates how to avoid selection bias by using random block sizes. PMID:21318011

  13. Random walks, random fields, and disordered systems

    CERN Document Server

    Černý, Jiří; Kotecký, Roman

    2015-01-01

    Focusing on the mathematics that lies at the intersection of probability theory, statistical physics, combinatorics and computer science, this volume collects together lecture notes on recent developments in the area. The common ground of these subjects is perhaps best described by the three terms in the title: Random Walks, Random Fields and Disordered Systems. The specific topics covered include a study of Branching Brownian Motion from the perspective of disordered (spin-glass) systems, a detailed analysis of weakly self-avoiding random walks in four spatial dimensions via methods of field theory and the renormalization group, a study of phase transitions in disordered discrete structures using a rigorous version of the cavity method, a survey of recent work on interacting polymers in the ballisticity regime and, finally, a treatise on two-dimensional loop-soup models and their connection to conformally invariant systems and the Gaussian Free Field. The notes are aimed at early graduate students with a mod...

  14. Random mapping statistics

    OpenAIRE

    Flajolet, Philippe; Odlyzko, Andrew M.

    1989-01-01

    Random mappings from a finite set into itself are either a heuristic or an exact model for a variety of applications in random number generation, computational number theory, cryptography, and the analysis of algorithms at large. This paper introduces a general framework in which the analysis of about twenty characteristic parameters of random mappings is carried out. These parameters are studied systematically through the use of generating functions and singularity analysis. In particular, a...

  15. Random Sampling with Removal

    OpenAIRE

    Gärtner, Bernd; Lengler, Johannes; Szedlak, May

    2015-01-01

    Random sampling is a classical tool in constrained optimization. Under favorable conditions, the optimal solution subject to a small subset of randomly chosen constraints violates only a small subset of the remaining constraints. Here we study the following variant that we call random sampling with removal: suppose that after sampling the subset, we remove a fixed number of constraints from the sample, according to an arbitrary rule. Is it still true that the optimal solution of the reduced s...

  16. Random fractal dendrites

    OpenAIRE

    Croydon, David (David Alexander); Hambly, Ben M.; Dr. Ben Hambly

    2006-01-01

    Dendrites are tree-like topological spaces, and in this thesis, the physical characteristics of various random fractal versions of this type of set are investigated. This work will contribute to the development of analysis on fractals, an area which has grown considerably over the last twenty years. First, a collection of random self-similar dendrites is constructed, and their Hausdorff dimension is calculated. Previous results determining this quantity for random self-simi...

  17. Misuse of randomization

    DEFF Research Database (Denmark)

    Liu, Jianping; Kjaergard, Lise Lotte; Gluud, Christian

    2002-01-01

    The quality of randomization of Chinese randomized trials on herbal medicines for hepatitis B was assessed. Search strategy and inclusion criteria were based on the published protocol. One hundred and seventy-six randomized clinical trials (RCTs) involving 20,452 patients with chronic hepatitis B...... virus (HBV) infection were identified that tested Chinese medicinal herbs. They were published in 49 Chinese journals. Only 10% (18/176) of the studies reported the method by which they randomized patients. Only two reported allocation concealment and were considered as adequate. Twenty percent (30...

  18. On Random Rough Sets

    Institute of Scientific and Technical Information of China (English)

    Weizhi Wu

    2006-01-01

    In this paper,the concept of a random rough set which includes the mechanisms of numeric and non-numeric aspects of uncertain knowledge is introduced. It is proved that for any belief structure and its inducing belief and plausibility measures there exists a random approximation space such that the associated lower and upper probabilities are respectively the given belief and plausibility measures, and vice versa. And for a random approximation space generated from a totally random set, its inducing lower and upper probabilities are respectively a pair of necessity and possibility measures.

  19. Rest versus exercise as treatment for patients with low back pain and Modic changes. a randomized controlled clinical trial

    Directory of Open Access Journals (Sweden)

    Jensen Rikke K

    2012-02-01

    Full Text Available Abstract Background Clinical experience suggests that many patients with Modic changes have relatively severe and persistent low back pain (LBP, which typically appears to be resistant to treatment. Exercise therapy is the recommended treatment for chronic LBP, however, due to their underlying pathology, Modic changes might be a diagnostic subgroup that does not benefit from exercise. The objective of this study was to compare the current state-of-the art treatment approach (exercise and staying active with a new approach (load reduction and daily rest for people with Modic changes using a randomized controlled trial design. Methods Participants were patients from an outpatient clinic with persistent LBP and Modic changes. They were allocated using minimization to either rest therapy for 10 weeks with a recommendation to rest for two hours daily and the option of using a flexible lumbar belt or exercise therapy once a week for 10 weeks. Follow-up was at 10 weeks after recruitment and 52 weeks after intervention and the clinical outcome measures were pain, disability, general health and global assessment, supplemented by weekly information on low back problems and sick leave measured by short text message (SMS tracking. Results In total, 100 patients were included in the study. Data on 87 patients at 10 weeks and 96 patients at one-year follow-up were available and were used in the intention-to-treat analysis. No statistically significant differences were found between the two intervention groups on any outcome. Conclusions No differences were found between the two treatment approaches, 'rest and reduced load' and 'exercise and staying active', in patients with persistent LBP and Modic changes. Trial Registration ClinicalTrials.gov: NCT00454792

  20. Asymptotics of Random Contractions

    CERN Document Server

    Hashorva, Enkelejd; Tang, Qihe

    2010-01-01

    In this paper we discuss the asymptotic behaviour of random contractions $X=RS$, where $R$, with distribution function $F$, is a positive random variable independent of $S\\in (0,1)$. Random contractions appear naturally in insurance and finance. Our principal contribution is the derivation of the tail asymptotics of $X$ assuming that $F$ is in the max-domain of attraction of an extreme value distribution and the distribution function of $S$ satisfies a regular variation property. We apply our result to derive the asymptotics of the probability of ruin for a particular discrete-time risk model. Further we quantify in our asymptotic setting the effect of the random scaling on the Conditional Tail Expectations, risk aggregation, and derive the joint asymptotic distribution of linear combinations of random contractions.

  1. Randomness: quantum versus classical

    CERN Document Server

    Khrennikov, Andrei

    2015-01-01

    Recent tremendous development of quantum information theory led to a number of quantum technological projects, e.g., quantum random generators. This development stimulates a new wave of interest in quantum foundations. One of the most intriguing problems of quantum foundations is elaboration of a consistent and commonly accepted interpretation of quantum state. Closely related problem is clarification of the notion of quantum randomness and its interrelation with classical randomness. In this short review we shall discuss basics of classical theory of randomness (which by itself is very complex and characterized by diversity of approaches) and compare it with irreducible quantum randomness. The second part of this review is devoted to the information interpretation of quantum mechanics (QM) in the spirit of Zeilinger and Brukner (and QBism of Fuchs et al.) and physics in general (e.g., Wheeler's "it from bit") as well as digital philosophy of Chaitin (with historical coupling to ideas of Leibnitz). Finally, w...

  2. Random bistochastic matrices

    Energy Technology Data Exchange (ETDEWEB)

    Cappellini, Valerio [' Mark Kac' Complex Systems Research Centre, Uniwersytet Jagiellonski, ul. Reymonta 4, 30-059 Krakow (Poland); Sommers, Hans-Juergen [Fachbereich Physik, Universitaet Duisburg-Essen, Campus Duisburg, 47048 Duisburg (Germany); Bruzda, Wojciech; Zyczkowski, Karol [Instytut Fizyki im. Smoluchowskiego, Uniwersytet Jagiellonski, ul. Reymonta 4, 30-059 Krakow (Poland)], E-mail: valerio@ictp.it, E-mail: h.j.sommers@uni-due.de, E-mail: w.bruzda@uj.edu.pl, E-mail: karol@cft.edu.pl

    2009-09-11

    Ensembles of random stochastic and bistochastic matrices are investigated. While all columns of a random stochastic matrix can be chosen independently, the rows and columns of a bistochastic matrix have to be correlated. We evaluate the probability measure induced into the Birkhoff polytope of bistochastic matrices by applying the Sinkhorn algorithm to a given ensemble of random stochastic matrices. For matrices of order N = 2 we derive explicit formulae for the probability distributions induced by random stochastic matrices with columns distributed according to the Dirichlet distribution. For arbitrary N we construct an initial ensemble of stochastic matrices which allows one to generate random bistochastic matrices according to a distribution locally flat at the center of the Birkhoff polytope. The value of the probability density at this point enables us to obtain an estimation of the volume of the Birkhoff polytope, consistent with recent asymptotic results.

  3. Random Bistochastic Matrices

    CERN Document Server

    Cappellini, V; Bruzda, W; Zyczkowski, K

    2009-01-01

    Ensembles of random stochastic and bistochastic matrices are investigated. While all columns of a random stochastic matrix can be chosen independently, the rows and columns of a bistochastic matrix have to be correlated. We evaluate the probability measure induced into the Birkhoff polytope of bistochastic matrices by applying the Sinkhorn algorithm to a given ensemble of random stochastic matrices. For matrices of order N=2 we derive explicit formulae for the probability distributions induced by random stochastic matrices with columns distributed according to the Dirichlet distribution. For arbitrary $N$ we construct an initial ensemble of stochastic matrices which allows one to generate random bistochastic matrices according to a distribution locally flat at the center of the Birkhoff polytope. The value of the probability density at this point enables us to obtain an estimation of the volume of the Birkhoff polytope, consistent with recent asymptotic results.

  4. Quantum random number generator

    Energy Technology Data Exchange (ETDEWEB)

    Pooser, Raphael C.

    2016-05-10

    A quantum random number generator (QRNG) and a photon generator for a QRNG are provided. The photon generator may be operated in a spontaneous mode below a lasing threshold to emit photons. Photons emitted from the photon generator may have at least one random characteristic, which may be monitored by the QRNG to generate a random number. In one embodiment, the photon generator may include a photon emitter and an amplifier coupled to the photon emitter. The amplifier may enable the photon generator to be used in the QRNG without introducing significant bias in the random number and may enable multiplexing of multiple random numbers. The amplifier may also desensitize the photon generator to fluctuations in power supplied thereto while operating in the spontaneous mode. In one embodiment, the photon emitter and amplifier may be a tapered diode amplifier.

  5. Random attractors for asymptotically upper semicompact multivalue random semiflows

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The present paper studied the dynamics of some multivalued random semiflow. The corresponding concept of random attractor for this case was introduced to study asymptotic behavior. The existence of random attractor of multivalued random semiflow was proved under the assumption of pullback asymptotically upper semicompact, and this random attractor is random compact and invariant. Furthermore, if the system has ergodicity, then this random attractor is the limit set of a deterministic bounded set.

  6. Protocol for Shoulder function training reducing musculoskeletal pain in shoulder and neck: a randomized controlled trial

    DEFF Research Database (Denmark)

    Andersen, Christoffer H; Andersen, Lars L; Mortensen, Ole S;

    2011-01-01

    ABSTRACT: BACKGROUND: Neck and shoulder complaints are common among employees in sedentary occupations characterized by intensive computer use. Such musculoskeletal pain - which is often associated with restricted range of motion and loss of muscle strength - is one of the most common conditions...... training of the painful area. Our study investigates the effect of the latter approach. METHODS/DESIGN: A randomized controlled trial of 10 weeks duration is currently being conducted. Employed office workers with severe neck-shoulder pain are randomized to 3 × 20 min shoulder function training...... including jobs characterized by intensive computer work. The first 100 positive replies entered the study. Among these inclusion criteria were pain intensity in the neck/shoulder of at least 3 on a 0-9 scale. Exclusion criteria were cardiovascular disease, trauma, hypertension, or serious chronic disease...

  7. Clinical and histological effect of a low glycaemic load diet in treatment of acne vulgaris in Korean patients: a randomized, controlled trial.

    Science.gov (United States)

    Kwon, Hyuck Hoon; Yoon, Ji Young; Hong, Jong Soo; Jung, Jae Yoon; Park, Mi Sun; Suh, Dae Hun

    2012-05-01

    Recent studies have suggested that dietary factors, specifically glycaemic load, may be involved in the pathogenesis of acne. The aim of this study was to determine the clinical and histological effects on acne lesions of a low glycaemic load diet. A total of 32 patients with mild to moderate acne were randomly assigned to either a low glycaemic load diet or a control group diet, and completed a 10-week, parallel dietary intervention trial. Results indicate successful lowering of the glycaemic load. Subjects within the low glycaemic group demonstrated significant clinical improvement in the number of both non-inflammatory and inflammatory acne lesions. Histopathological examination of skin samples revealed several characteristics, including reduced size of sebaceous glands, decreased inflammation, and reduced expression of sterol regulatory element-binding protein-1, and interleukin-8 in the low glycaemic load group. A reduction in glycaemic load of the diet for 10 weeks resulted in improvements in acne. PMID:22678562

  8. Random Fiber Laser

    CERN Document Server

    de Matos, Christiano J S; Brito-Silva, Antônio M; Gámez, M A Martinez; Gomes, Anderson S L; de Araújo, Cid B

    2007-01-01

    We investigate the effects of two dimensional confinement on the lasing properties of a classical random laser system operating in the incoherent feedback (diffusive) regime. A suspension of 250nm rutile (TiO2) particles in a Rhodamine 6G solution was inserted into the hollow core of a photonic crystal fiber (PCF) generating the first random fiber laser and a novel quasi-one-dimensional RL geometry. Comparison with similar systems in bulk format shows that the random fiber laser presents an efficiency that is at least two orders of magnitude higher.

  9. Invitation to random tensors

    CERN Document Server

    Gurau, Razvan

    2016-01-01

    Preface to the SIGMA special issue "Tensor Models, Formalism and Applications." The SIGMA special issue "Tensor Models, Formalism and Applications" is a collection of eight excellent, up to date reviews \\cite{Ryan:2016sundry,Bonzom:2016dwy,Rivasseau:2016zco,Carrozza:2016vsq,Krajewski:2016svb,Rivasseau:2016rgt,Tanasa:2015uhr,Gielen:2016dss} on random tensor models. The reviews combine pedagogical introductions meant for a general audience with presentations of the most recent developments in the field. This preface aims to give a condensed panoramic overview of random tensors as the natural generalization of random matrices to higher dimensions.

  10. Quantum random access memory

    OpenAIRE

    Giovannetti, Vittorio; Lloyd, Seth; Maccone, Lorenzo

    2007-01-01

    A random access memory (RAM) uses n bits to randomly address N=2^n distinct memory cells. A quantum random access memory (qRAM) uses n qubits to address any quantum superposition of N memory cells. We present an architecture that exponentially reduces the requirements for a memory call: O(log N) switches need be thrown instead of the N used in conventional (classical or quantum) RAM designs. This yields a more robust qRAM algorithm, as it in general requires entanglement among exponentially l...

  11. Random Fiber Laser

    OpenAIRE

    Christiano J. S. de Matos; Menezes, Leonardo de S.; Brito-Silva, Antônio M.; Gámez, M. A. Martinez; Gomes, Anderson S. L.; de Araújo, Cid B.

    2007-01-01

    We investigate the effects of two dimensional confinement on the lasing properties of a classical random laser system operating in the incoherent feedback (diffusive) regime. A suspension of 250nm rutile (TiO2) particles in a Rhodamine 6G solution was inserted into the hollow core of a photonic crystal fiber (PCF) generating the first random fiber laser and a novel quasi-one-dimensional RL geometry. Comparison with similar systems in bulk format shows that the random fiber laser presents an e...

  12. A random walk with a branching system in random environments

    Institute of Scientific and Technical Information of China (English)

    Ying-qiu LI; Xu LI; Quan-sheng LIU

    2007-01-01

    We consider a branching random walk in random environments, where the particles are reproduced as a branching process with a random environment (in time), and move independently as a random walk on Z with a random environment (in locations). We obtain the asymptotic properties on the position of the rightmost particle at time n, revealing a phase transition phenomenon of the system.

  13. Random maintenance policies

    CERN Document Server

    Nakagawa, Toshio

    2014-01-01

    Exploring random maintenance models, this book provides an introduction to the implementation of random maintenance, and it is one of the first books to be written on this subject.  It aims to help readers learn new techniques for applying random policies to actual reliability models, and it provides new theoretical analyses of various models including classical replacement, preventive maintenance and inspection policies. These policies are applied to scheduling problems, backup policies of database systems, maintenance policies of cumulative damage models, and reliability of random redundant systems. Reliability theory is a major concern for engineers and managers, and in light of Japan’s recent earthquake, the reliability of large-scale systems has increased in importance. This also highlights the need for a new notion of maintenance and reliability theory, and how this can practically be applied to systems. Providing an essential guide for engineers and managers specializing in reliability maintenance a...

  14. Spiders in random environment

    CERN Document Server

    Gallesco, Christophe; Popov, Serguei; Vachkovskaia, Marina

    2010-01-01

    A spider consists of several, say $N$, particles. Particles can jump independently according to a random walk if the movement does not violate some given restriction rules. If the movement violates a rule it is not carried out. We consider random walk in random environment (RWRE) on $\\Z$ as underlying random walk. We suppose the environment $\\omega=(\\omega_x)_{x \\in \\Z}$ to be elliptic, with positive drift and nestling, so that there exists a unique positive constant $\\kappa$ such that $\\E[((1-\\omega_0)/\\omega_0)^{\\kappa}]=1$. The restriction rules are kept very general; we only assume transitivity and irreducibility of the spider. The main result is that the speed of a spider is positive if $\\kappa/N>1$ and null if $\\kappa/N<1$. In particular, if $\\kappa/N <1$ a spider has null speed but the speed of a (single) RWRE is positive.

  15. Tunable random packings

    International Nuclear Information System (INIS)

    We present an experimental protocol that allows one to tune the packing fraction η of a random pile of ferromagnetic spheres from a value close to the lower limit of random loose packing ηRLP≅0.56 to the upper limit of random close packing ηRCP≅0.64. This broad range of packing fraction values is obtained under normal gravity in air, by adjusting a magnetic cohesion between the grains during the formation of the pile. Attractive and repulsive magnetic interactions are found to affect stongly the internal structure and the stability of sphere packing. After the formation of the pile, the induced cohesion is decreased continuously along a linear decreasing ramp. The controlled collapse of the pile is found to generate various and reproducible values of the random packing fraction η

  16. Random unistochastic matrices

    OpenAIRE

    Zyczkowski, K.; Slomczynski, W.; Kus, M.; Sommers, H. -J.

    2001-01-01

    An ensemble of random unistochastic (orthostochastic) matrices is defined by taking squared moduli of elements of random unitary (orthogonal) matrices distributed according to the Haar measure on U(N) (or O(N), respectively). An ensemble of symmetric unistochastic matrices is obtained with use of unitary symmetric matrices pertaining to the circular orthogonal ensemble. We study the distribution of complex eigenvalues of bistochastic, unistochastic and ortostochastic matrices in the complex p...

  17. Randomized Aperture Imaging

    CERN Document Server

    Peng, Xiaopeng; Swartzlander, Grover A

    2016-01-01

    Speckled images of a binary broad band light source (600-670 nm), generated by randomized reflections or transmissions, were used to reconstruct a binary image by use of multi-frame blind deconvolution algorithms. Craft store glitter was used as reflective elements. Another experiment used perforated foil. Also reported here are numerical models that afforded controlled tip-tilt and piston aberrations. These results suggest the potential importance of a poorly figured, randomly varying segmented imaging system.

  18. Generating random density matrices

    CERN Document Server

    Zyczkowski, Karol; Nechita, Ion; Collins, Benoit

    2010-01-01

    We study various methods to generate ensembles of quantum density matrices of a fixed size N and analyze the corresponding probability distributions P(x), where x denotes the rescaled eigenvalue, x=N\\lambda. Taking a random pure state of a two-partite system and performing the partial trace over one subsystem one obtains a mixed state represented by a Wishart--like matrix W=GG^{\\dagger}, distributed according to the induced measure and characterized asymptotically, as N -> \\infty, by the Marchenko-Pastur distribution. Superposition of k random maximally entangled states leads to another family of explicitly derived distributions, describing singular values of the sum of k independent random unitaries. Taking a larger system composed of 2s particles, constructing $s$ random bi-partite states, performing the measurement into a product of s-1 maximally entangled states and performing the partial trace over the remaining subsystem we arrive at a random state characterized by the Fuss-Catalan distribution of order...

  19. A randomized, controlled study of an online intervention to promote job satisfaction and well-being among physicians

    Directory of Open Access Journals (Sweden)

    Liselotte N. Dyrbye

    2016-09-01

    Full Text Available Although burnout, poor quality of life (QOL, depression, and other forms of psychological distress are common among physicians, few studies testing interventions to reduce distress have been reported. We conducted a randomized trial to determine the impact of a 10-week, individualized, online intervention on well-being among physicians (n = 290. Participants were randomized to either the intervention or control arm. Those in the intervention arm received a menu of self-directed micro-tasks once a week for 10 weeks, and were asked to select and complete one task weekly. Baseline and end-of-study questionnaires evaluating well-being (i.e., burnout, depression, QOL, fatigue and professional satisfaction (i.e., job satisfaction, work engagement, meaning in work, and satisfaction with work-life balance were administered to both arms. Overall quality of life and fatigue improved over the 10 weeks of the study for those in the intervention arm (both p < 0.01. When compared to the control arm, however, no statistically significant improvement in these dimensions of well-being was observed. At the completion of the study, those in the intervention arm were more likely to report participating in the study was worthwhile compared to those in the control arm. The findings suggest that although participants found the micro-tasks in the intervention arm worthwhile, they did not result in measurable improvements in well-being or professional satisfaction when compared to the control group. These results also highlight the critical importance of an appropriate control group in studies evaluating interventions to address physician burnout and distress.

  20. Graphene random laser

    CERN Document Server

    Marini, Andrea

    2015-01-01

    Manipulating and controlling the optical energy flow inside random media is a research frontier of photonics and the basis of novel laser designs. In particular, light amplification in randomly dispersed active inclusions under external pumping has been extensively investigated, although it still lacks external tunability, reproducibility, and control over the beam spatial pattern, thus hindering its application in practical devices. Here we show that a graphene random metamaterial provides the means to overcome these limitations through its extraordinarily-low threshold for saturable absorption. The nonlinear properties of nano-graphene combined with an optically pumped gain medium allow us to controllably tune the system from chaotic to stable single-mode lasing. Our results hold great potential for the development of single-mode cavity-free lasers with engineered beam patterns in disordered media.

  1. Drawing a random number

    DEFF Research Database (Denmark)

    Wanscher, Jørgen Bundgaard; Sørensen, Majken Vildrik

    2006-01-01

    Random numbers are used for a great variety of applications in almost any field of computer and economic sciences today. Examples ranges from stock market forecasting in economics, through stochastic traffic modelling in operations research to photon and ray tracing in graphics. The construction...... of a model or a solution method requires certain characteristics of the random numbers used. This is usually a distribution classification, which the sequence of random numbers must fulfill; of these some are very hard to fulfill and others are next to impossible. Today mathematics allows us to transform...... distributions into others with most of the required characteristics. In essence, a uniform sequence which is transformed into a new sequence with the required distribution. The subject of this article is to consider the well known highly uniform Halton sequence and modifications to it. The intent is to generate...

  2. Random copying in space

    CERN Document Server

    Blythe, Richard A

    2011-01-01

    Random copying is a simple model for population dynamics in the absence of selection, and has been applied to both biological and cultural evolution. In this work, we investigate the effect that spatial structure has on the dynamics. We focus in particular on how a measure of the diversity in the population changes over time. We show that even when the vast majority of a population's history may be well-described by a spatially-unstructured model, spatial structure may nevertheless affect the expected level of diversity seen at a local scale. We demonstrate this phenomenon explicitly by examining the random copying process on small-world networks, and use our results to comment on the use of simple random-copying models in an empirical context.

  3. Random errors revisited

    DEFF Research Database (Denmark)

    Jacobsen, Finn

    2000-01-01

    It is well known that the random errors of sound intensity estimates can be much larger than the theoretical minimum value determined by the BT-product, in particular under reverberant conditions and when there are several sources present. More than ten years ago it was shown that one can predict...... the random errors of estimates of the sound intensity in, say, one-third octave bands from the power and cross power spectra of the signals from an intensity probe determined with a dual channel FFT analyser. This is not very practical, though. In this paper it is demonstrated that one can predict the...... random errors from the power and cross power spectra determined with the same spectral resolution as the sound intensity itself....

  4. Random hypergraphs and algorithmics

    CERN Document Server

    Andriamampianina, Tsiriniaina

    2008-01-01

    Hypergraphs are structures that can be decomposed or described; in other words they are recursively countable. Here, we get exact and asymptotic enumeration results on hypergraphs by mean of exponential generating functions. The number of hypergraph component is bounded, as a generalisation of Wright inequalities for graphs: the proof is a combinatorial understanding of the structure by inclusion exclusion. Asymptotic results are obtained, thanks to generating functions proofs are at the end very easy to read, through complex analysis by saddle point method. By this way, we characterized: - the components with a given number of vertices and of hyperedges by the expected size of a random hypermatching in these structures. - the random hypergraphs (evolving hyperedge by hyperedge) according to the expected number of hyperedges when the first cycle appears in the evolving structure. This work is an open road to further works on random hypergraphs such as threshold phenomenon, tools used here seem to be sufficien...

  5. Free Completely Random Measures

    CERN Document Server

    Collet, Francesca

    2011-01-01

    Free probability is a noncommutative probability theory introduced by Voiculescu where the concept of independence of classical probability is replaced by the concept of freeness. An important connection between free and classical infinitely divisibility was established by Bercovici and Pata (1999) in form of a bijection, mapping the class of classical infinitely divisible laws into the class of free infinitely divisible laws. A particular class of infinitely divisible laws are the completely random measures introduced by Kingman (1967). In this paper, a free analogous of completely random measures is introduced and, a free Poisson process characterization is provided as well as a representation through a free cumulant transform. Furthermore, some examples are displayed.

  6. Random quantum operations

    Energy Technology Data Exchange (ETDEWEB)

    Bruzda, Wojciech [Mark Kac Complex Systems Research Centre, Institute of Physics, Jagiellonian University, ul. Reymonta 4, 30-059 Krakow (Poland)], E-mail: wojtek@gorce.if.uj.edu.pl; Cappellini, Valerio [Mark Kac Complex Systems Research Centre, Institute of Physics, Jagiellonian University, ul. Reymonta 4, 30-059 Krakow (Poland); Sommers, Hans-Juergen [Fachbereich Physik, Universitaet Duisburg-Essen, Campus Duisburg, 47048 Duisburg (Germany); Zyczkowski, Karol [Mark Kac Complex Systems Research Centre, Institute of Physics, Jagiellonian University, ul. Reymonta 4, 30-059 Krakow (Poland); Centrum Fizyki Teoretycznej, Polska Akademia Nauk, Al. Lotnikow 32/44, 02-668 Warszawa (Poland)

    2009-01-12

    We define a natural ensemble of trace preserving, completely positive quantum maps and present algorithms to generate them at random. Spectral properties of the superoperator {phi} associated with a given quantum map are investigated and a quantum analogue of the Frobenius-Perron theorem is proved. We derive a general formula for the density of eigenvalues of {phi} and show the connection with the Ginibre ensemble of real non-symmetric random matrices. Numerical investigations of the spectral gap imply that a generic state of the system iterated several times by a fixed generic map converges exponentially to an invariant state.

  7. Random unistochastic matrices

    Energy Technology Data Exchange (ETDEWEB)

    Zyczkowski, Karol [Centrum Fizyki Teoretycznej, Polska Akademia Nauk, Al. Lotnikow 32/44, 02-668 Warsaw (Poland); Kus, Marek [Centrum Fizyki Teoretycznej, Polska Akademia Nauk, Al. Lotnikow 32/44, 02-668 Warsaw (Poland); Slomczynski, Wojciech [Instytut Matematyki, Uniwersytet Jagiellonski, ul. Reymonta 4, 30-059 Cracow (Poland); Sommers, Hans-Juergen [Fachbereich 7 Physik, Universitaet Essen, 45117 Essen (Germany)

    2003-03-28

    An ensemble of random unistochastic (orthostochastic) matrices is defined by taking squared moduli of elements of random unitary (orthogonal) matrices distributed according to the Haar measure on U(N) (or O(N)). An ensemble of symmetric unistochastic matrices is obtained with use of unitary symmetric matrices pertaining to the circular orthogonal ensemble. We study the distribution of complex eigenvalues of bistochastic, unistochastic and orthostochastic matrices in the complex plane. We compute averages (entropy, traces) over the ensembles of unistochastic matrices and present inequalities concerning the entropies of products of bistochastic matrices.

  8. Delayed Random Relays

    CERN Document Server

    Ohira, Toru

    2016-01-01

    We present here a system with collection of random walks relaying a signal in one dimension with a presence of a delay. We are interested in the time for a signal to travel from one end (start) to the other end (finish) of the lined group of random walkers. It is found that there is an optimal number of walkers for the signal to travel fastest if the delay is present. We discuss implications of this model and associated behaviors to physical and biological systems.

  9. RANDOM SINGULAR INTEGRAL OF RANDOM PROCESS WITH SECOND ORDER MOMENT

    Institute of Scientific and Technical Information of China (English)

    Wang Chuanrong

    2005-01-01

    This paper discussses the random singular integral of random process with second order moment, establishes the concepts of the random singular integral and proves that it's a linear bounded operator of space Hα(L)(m, s). Then Plemelj formula and some other properties for random singular integral are proved.

  10. Coded Random Access

    DEFF Research Database (Denmark)

    Paolini, Enrico; Stefanovic, Cedomir; Liva, Gianluigi;

    2015-01-01

    as waste. However, if the common receiver (e.g., base station) is capable to store the collision slots and use them in a transmission recovery process based on successive interference cancellation, the design space for access protocols is radically expanded. We present the paradigm of coded random access...

  11. Randomness Of Amoeba Movements

    Science.gov (United States)

    Hashiguchi, S.; Khadijah, Siti; Kuwajima, T.; Ohki, M.; Tacano, M.; Sikula, J.

    2005-11-01

    Movements of amoebas were automatically traced using the difference between two successive frames of the microscopic movie. It was observed that the movements were almost random in that the directions and the magnitudes of the successive two steps are not correlated, and that the distance from the origin was proportional to the square root of the step number.

  12. Photographic dataset: random peppercorns

    CERN Document Server

    Helenius, Teemu

    2016-01-01

    This is a photographic dataset collected for testing image processing algorithms. The idea is to have sets of different but statistically similar images. In this work the images show randomly distributed peppercorns. The dataset is made available at www.fips.fi/photographic_dataset.php .

  13. Asymmetric Carrier Random PWM

    DEFF Research Database (Denmark)

    Mathe, Laszlo; Lungeanu, Florin; Rasmussen, Peter Omand;

    2010-01-01

    This paper presents a new fixed carrier frequency random PWM method, where a new type of carrier wave is proposed for modulation. Based on the measurements, it is shown that the spread effect of the discrete components from the motor current spectra is very effective independent of the modulation...

  14. Testing for Subcellular Randomness

    CERN Document Server

    Okunoye, Babatunde O

    2008-01-01

    Statistical tests were conducted on 1,000 numbers generated from the genome of Bacteriophage T4, obtained from GenBank with accession number AF158101.The numbers passed the non-parametric, distribution-free tests.Deoxyribonucleic acid was discovered to be a random number generator, existent in nature.

  15. Randomized controlled trial comparing four strategies for delivering e-curriculum to health care professionals [ISRCTN88148532

    Directory of Open Access Journals (Sweden)

    Mitra Ananda

    2006-01-01

    Full Text Available Abstract Background Internet education is increasingly provided to health professionals, but little is known about the most effective strategies for delivering the content. The purpose of this study is to compare four strategies for delivering an Internet-based (e- curriculum on clinicians' knowledge (K, confidence (CONF, and communication (COMM about herbs and other dietary supplements (HDS. Methods This national randomized 2 × 2 factorial trial included physicians, pharmacists, nurses, nutritionists and trainees in these fields. Participants were randomly assigned to one of four curriculum delivery strategies for 40 brief modules about HDS: a delivering four (4 modules weekly over ten (10 weeks by email (drip-push; b modules accessible on web site with 4 reminders weekly for 10 weeks (drip-pull; c 40 modules delivered within 4 days by email (bolus-push; and d 40 modules available on the Internet with one email informing participants of availability (bolus-pull. Results Of the 1,267 enrollees, 25% were male; the average age was 40 years. The completion rate was 62%, without significant differences between delivery groups. There were statistically significant improvements in K, CONF and COMM scores after the course (P Conclusion All delivery strategies tested similarly improved K, CONF, COMM scores about HDS. Educators can use the strategy that is most convenient without diminishing effectiveness. Additional curricula may be necessary to make substantial changes in clinicians' communication practices.

  16. Exponential random graph models

    CERN Document Server

    Fronczak, Agata

    2012-01-01

    Nowadays, exponential random graphs (ERGs) are among the most widely-studied network models. Different analytical and numerical techniques for ERG have been developed that resulted in the well-established theory with true predictive power. An excellent basic discussion of exponential random graphs addressed to social science students and researchers is given in [Anderson et al., 1999][Robins et al., 2007]. This essay is intentionally designed to be more theoretical in comparison with the well-known primers just mentioned. Given the interdisciplinary character of the new emerging science of complex networks, the essay aims to give a contribution upon which network scientists and practitioners, who represent different research areas, could build a common area of understanding.

  17. Hashing, Randomness and Dictionaries

    DEFF Research Database (Denmark)

    Pagh, Rasmus

    time and memory space. To some extent we also consider lower bounds, i.e., we attempt to show limitations on how efficient algorithms are possible. A central theme in the thesis is randomness. Randomized algorithms play an important role, in particular through the key technique of hashing. Additionally...... algorithms community. We work (almost) exclusively with a model, a mathematical object that is meant to capture essential aspects of a real computer. The main model considered here (and in most of the literature on dictionaries) is a unit cost RAM with a word size that allows a set element to be stored...... in one word. We consider several variants of the dictionary problem, as well as some related problems. The problems are studied mainly from an upper bound perspective, i.e., we try to come up with algorithms that are as efficient as possible with respect to various computing resources, mainly computation...

  18. Random very loose packings.

    Science.gov (United States)

    Ciamarra, Massimo Pica; Coniglio, Antonio

    2008-09-19

    We measure the number Omega(phi) of mechanically stable states of volume fraction phi of a granular assembly under gravity. The granular entropy S(phi)=logOmega(phi) vanishes both at high density, at phi approximately equal to phi_rcp, and a low density, at phi approximately equal to phi_rvlp, where phi_rvlp is a new lower bound we call random very loose pack. phi_rlp is the volume fraction where the entropy is maximal. These findings allow for a clear explanation of compaction experiments and provide the first first-principle definition of the random loose volume fraction. In the context of the statistical mechanics approach to static granular materials, states with phi

  19. On fairness and randomness

    DEFF Research Database (Denmark)

    Jaeger, Manfred

    2009-01-01

    We investigate the relation between the behavior of non-deterministic systems under fairness constraints, and the behavior of probabilistic systems. To this end, first a framework based on computable stopping strategies is developed that provides a common foundation for describing both fair...... and probabilistic behavior. On the basis of stopping strategies it is then shown that fair behavior corresponds in a precise sense to random behavior in the sense of Martin-Löf's definition of randomness. We view probabilistic systems as concrete implementations of more abstract non-deterministic systems. Under...... this perspective the question is investigated what probabilistic properties are needed in such an implementation to guarantee (with probability one) certain required fairness properties in the behavior of the probabilistic system. Generalizing earlier concepts of ε -bounded transition probabilities, we introduce...

  20. Random Raman lasing

    CERN Document Server

    Hokr, Brett H; Mason, John D; Beier, Hope T; Rockwll, Benjamin A; Thomas, Robert J; Noojin, Gary D; Petrov, Georgi I; Golovan, Leonid A; Yakovlev, Vladislav V

    2013-01-01

    Propagation of light in a highly scattering medium is among the most fascinating optical effect that everyone experiences on an everyday basis and possesses a number of fundamental problems which have yet to be solved. Conventional wisdom suggests that non-linear effects do not play a significant role because the diffusive nature of scattering acts to spread the intensity, dramatically weakening these effects. We demonstrate the first experimental evidence of lasing on a Raman transition in a bulk three-dimensional random media. From a practical standpoint, Raman transitions allow for spectroscopic analysis of the chemical makeup of the sample. A random Raman laser could serve as a bright Raman source allowing for remote, chemically specific, identification of powders and aerosols. Fundamentally, the first demonstration of this new light source opens up an entire new field of study into non-linear light propagation in turbid media, with the most notable application related to non-invasive biomedical imaging.

  1. Decorating random quadrangulations

    International Nuclear Information System (INIS)

    On various regular lattices (simple cubic, body centred cubic, etc) decorating an edge with an Ising spin coupled by bonds of strength L to the original vertex spins and competing with a direct anti-ferromagnetic bond of strength αL can give rise to three transition temperatures for suitable α. The system passes through ferromagnetic, paramagnetic, anti-ferromagnetic and paramagnetic phases respectively as the temperature is increased. For the square lattice on the other hand, multiple decoration is required to see this effect. We note here that a single decoration suffices for the Ising model on planar random quadrangulations (coupled to 2D quantum gravity). Other random bipartite lattices such as the Penrose tiling are more akin to the regular square lattice and require multiple decoration to have any affect. (author). Letter-to-the-editor

  2. Decorating random quadrangulations

    Energy Technology Data Exchange (ETDEWEB)

    Johnston, Desmond A. [Department of Mathematics, Heriot-Watt University, Riccarton, Edinburgh (United Kingdom); Malmini, Ranasinghe P.K.C. [Department of Mathematics, University of Sri Jayewardenepura, Gangodawila (Sri Lanka)

    2002-02-22

    On various regular lattices (simple cubic, body centred cubic, etc) decorating an edge with an Ising spin coupled by bonds of strength L to the original vertex spins and competing with a direct anti-ferromagnetic bond of strength {alpha}L can give rise to three transition temperatures for suitable {alpha}. The system passes through ferromagnetic, paramagnetic, anti-ferromagnetic and paramagnetic phases respectively as the temperature is increased. For the square lattice on the other hand, multiple decoration is required to see this effect. We note here that a single decoration suffices for the Ising model on planar random quadrangulations (coupled to 2D quantum gravity). Other random bipartite lattices such as the Penrose tiling are more akin to the regular square lattice and require multiple decoration to have any affect. (author). Letter-to-the-editor.

  3. On Complex Random Variables

    Directory of Open Access Journals (Sweden)

    Anwer Khurshid

    2012-07-01

    Full Text Available Normal 0 false false false EN-US X-NONE X-NONE In this paper, it is shown that a complex multivariate random variable  is a complex multivariate normal random variable of dimensionality if and only if all nondegenerate complex linear combinations of  have a complex univariate normal distribution. The characteristic function of  has been derived, and simpler forms of some theorems have been given using this characterization theorem without assuming that the variance-covariance matrix of the vector  is Hermitian positive definite. Marginal distributions of  have been given. In addition, a complex multivariate t-distribution has been defined and the density derived. A characterization of the complex multivariate t-distribution is given. A few possible uses of this distribution have been suggested.

  4. a randomized, controlled trial

    OpenAIRE

    Reinecke, Franziska

    2010-01-01

    The polycystic ovarian syndrome (PCOS) is characterized by hyperandrogenism and associated with obesity and impaired glucose metabolism. Despite the high prevalence of PCOS and the considerable clinical impact, the precise interplay between metabolism and hyperandrogenemia is not entirely clear. To analyse the effects of intravenous lipid and heparin infusion on circulating androgen levels in healthy women, we performed a randomized controlled cross-over trial. 12 healthy young women durin...

  5. Randomly Wired Multistage Networks

    OpenAIRE

    Maggs, Bruce M.

    1993-01-01

    Randomly wired multistage networks have recently been shown to outperform traditional multistage networks in three respects. First, they have fast deterministic packet-switching and circuit-switching algorithms for routing permutations. Second, they are nonblocking, and there are on-line algorithms for establishing new connections in them, even if many requests for connections are made simultaneously. Finally, and perhaps most importantly, they are highly fault tolerant.

  6. Random Conformal Weldings

    CERN Document Server

    Astala, K; Kupiainen, A; Saksman, E

    2009-01-01

    We construct a conformally invariant random family of closed curves in the plane by welding of random homeomorphisms of the unit circle. The homeomorphism is constructed using the exponential of $\\beta X$ where $X$ is the restriction of the two dimensional free field on the circle and the parameter $\\beta$ is in the "high temperature" regime $\\beta<\\sqrt 2$. The welding problem is solved by studying a non-uniformly elliptic Beltrami equation with a random complex dilatation. For the existence a method of Lehto is used. This requires sharp probabilistic estimates to control conformal moduli of annuli and they are proven by decomposing the free field as a sum of independent fixed scale fields and controlling the correlations of the complex dilation restricted to dyadic cells of various scales. For uniqueness we invoke a result by Jones and Smirnov on conformal removability of H\\"older curves. We conjecture that our curves are locally related to SLE$(\\kappa)$ for $\\kappa<4$.

  7. Randomized Multicenter Feasibility Trial of Myofascial Physical Therapy for Treatment of Urologic Chronic Pelvic Pain Syndrome

    Science.gov (United States)

    FitzGerald, Mary P; Anderson, Rodney U; Potts, Jeannette; Payne, Christopher K; Peters, Kenneth M; Clemens, J Quentin; Kotarinos, Rhonda; Fraser, Laura; Cosby, Annamarie; Fortman, Carole; Neville, Cynthia; Badillo, Suzanne; Odabachian, Lisa; Sanfield, Anna; O’Dougherty, Betsy; Halle-Podell, Rick; Cen, Liyi; Chuai, Shannon; Landis, J Richard; Kusek, John W; Nyberg, Leroy M

    2010-01-01

    Objectives To determine the feasibility of conducting a randomized clinical trial designed to compare two methods of manual therapy (myofascial physical therapy (MPT) and global therapeutic massage (GTM)) among patients with urologic chronic pelvic pain syndromes. Materials and Methods Our goal was to recruit 48 subjects with chronic prostatitis/chronic pelvic pain syndrome or interstitial cystitis/painful bladder syndrome at six clinical centers. Eligible patients were randomized to either MPT or GTM and were scheduled to receive up to 10 weekly treatments, each 1 hour in duration. Criteria to assess feasibility included adherence of therapists to prescribed therapeutic protocol as determined by records of treatment, adverse events which occurred during study treatment, and rate of response to therapy as assessed by the Patient Global Response Assessment (GRA). Primary outcome analysis compared response rates between treatment arms using Mantel-Haenszel methods. Results Twenty-three (49%) men and 24 (51%) women were randomized over a six month period. Twenty-four (51%) patients were randomized to GTM, 23 (49%) to MPT; 44 (94%) patients completed the study. Therapist adherence to the treatment protocols was excellent. The GRA response rate of 57% in the MPT group was significantly higher than the rate of 21% in the GTM treatment group (p=0.03). Conclusions The goals to judge feasibility of conducting a full-scale trial of physical therapy methods were met. The preliminary findings of a beneficial effect of MPT warrants further study. PMID:19535099

  8. Acemannan hydrogel dressing versus saline dressing for pressure ulcers. A randomized, controlled trial.

    Science.gov (United States)

    Thomas, D R; Goode, P S; LaMaster, K; Tennyson, T

    1998-10-01

    Aloe vera has been used for centuries as a topical treatment for various conditions and as a cathartic. An amorphous hydrogel dressing derived from the aloe plant (Carrasyn Gel Wound Dressing, Carrington Laboratories, Inc., Irving, TX) is approved by the Food and Drug Administration for the management of Stages I through IV pressure ulcers. To evaluate effectiveness of this treatment, 30 patients were randomized to receive either daily topical application of the hydrogel study dressing (acemannan hydrogel wound dressing) or a moist saline gauze dressing. Complete healing of the study ulcer occurred in 19 of 30 subjects (63%) during the 10-week observation period. No difference was observed in complete healing between the experimental and the control groups (odds ratio 0.93, 95% CI 0.16, 5.2). This study indicates that the acemannan hydrogel dressing is as effective as, but is not superior to, a moist saline gauze wound dressing for the management of pressure ulcers. PMID:10326343

  9. Quenched moderate deviations principle for random walk in random environment

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    We derive a quenched moderate deviations principle for the one-dimensional nearest random walk in random environment,where the environment is assumed to be stationary and ergodic.The approach is based on hitting time decomposition.

  10. Random Response of Linear Viscoelastic Systems under Random Excitation

    Institute of Scientific and Technical Information of China (English)

    张天舒; 方同

    2001-01-01

    A method of analyzing random response of linear viscoelastic systems under random excitation has been presented. The covariance matrices of random responses of a single-degree-freedom linear viscoelastic system subjected to stationary white noise and filtered white noise excitations have been obtained in closed form. For illustration, a numerical example has been included. It is observed that viscoelasticity has damping effect on the mean square random responses of the system, the higher is viscoelastic behavior, the higher the damping effect.

  11. Effect of Workplace- versus Home-Based Physical Exercise on Muscle Response to Sudden Trunk Perturbation among Healthcare Workers: A Cluster Randomized Controlled Trial

    OpenAIRE

    Jakobsen, Markus D.; Emil Sundstrup; Mikkel Brandt; Kenneth Jay; Per Aagaard; Andersen, Lars L.

    2015-01-01

    Objectives. The present study investigates the effect of workplace- versus home-based physical exercise on muscle reflex response to sudden trunk perturbation among healthcare workers. Methods. Two hundred female healthcare workers (age: 42 [SD 11], BMI: 24 [SD 4], and pain intensity: 3.1 [SD 2.2] on a scale of 0–10) from 18 departments at three hospitals were randomized at the cluster level to 10 weeks of (1) workplace physical exercise (WORK) performed in groups during working hours for 5 ×...

  12. Effect of Amitriptyline and Escitalopram on Functional Dyspepsia: a Multi-Center, Randomized, Controlled Study

    Science.gov (United States)

    Talley, Nicholas J.; Locke, G. Richard; Saito, Yuri A.; Almazar, Ann E.; Bouras, Ernest P.; Howden, Colin W.; Lacy, Brian E.; DiBaise, John K.; Prather, Charlene M.; Abraham, Bincy P.; El-Serag, Hashem B.; Moayyedi, Paul; Herrick, Linda M.; Szarka, Lawrence A.; Camilleri, Michael; Hamilton, Frank A.; Schleck, Cathy D.; Tilkes, Katherine E.; Zinsmeister, Alan R.

    2015-01-01

    Background & Aims Anti-depressants are frequently prescribed to treat functional dyspepsia (FD), a common disorder characterized by upper abdominal symptoms, including discomfort or post-prandial fullness. However, there is little evidence for the efficacy of these drugs in patients with FD. We performed a randomized, double-blind, placebo-controlled trial to evaluate the effects of anti-depressant therapy effects on symptoms, gastric emptying (GE), and mealinduced satiety in patients with FD. Methods We performed a study at 8 North American sites of patients who met the Rome II criteria for FD and did not have depression or use anti-depressants. Subjects (n=292; 44±15 y old, 75% female, 70% with dysmotility-like FD, and 30% with ulcer-like FD) were randomly assigned to groups given placebo, 50 mg amitriptyline, or 10 mg escitalopram for 10 weeks. The primary endpoint was adequate relief of FD symptoms for ≥5 weeks of the last 10 weeks (out of 12). Secondary endpoints included GE time, maximum tolerated volume in a nutrient drink test, and FD-related quality of life. Results An adequate relief response was reported by 39 subjects given placebo (40%), 51 given amitriptyline (53%), and 37 given escitalopram (38%) (P=.05, following treatment, adjusted for baseline balancing factors including all subjects). Subjects with ulcer-like FD given amitriptyline were more than 3-fold more likely to report adequate relief than those given placebo (odds ratio=3.1; 95% confidence interval, 1.1–9.0). Neither amitriptyline nor escitalopram appeared to affect GE or meal-induced satiety after the 10 week period in any group. Subjects with delayed GE were less likely to report adequate relief than subjects with normal GE (odds ratio=0.4; 95% confidence interval, 0.2–0.8). Both anti-depressants improved overall quality-of-life. Conclusions Amitriptyline, but not escitalopram, appears to benefit some patients with FD— particularly those with ulcer-like (painful) FD. Patients

  13. Randomizing Roaches: Exploring the "Bugs" of Randomization in Experimental Design

    Science.gov (United States)

    Wagler, Amy; Wagler, Ron

    2014-01-01

    Understanding the roles of random selection and random assignment in experimental design is a central learning objective in most introductory statistics courses. This article describes an activity, appropriate for a high school or introductory statistics course, designed to teach the concepts, values and pitfalls of random selection and assignment…

  14. ON THE RANGE OF RANDOM WALKS IN RANDOM ENVIRONMENT

    Institute of Scientific and Technical Information of China (English)

    ZHOUXIANYIN

    1995-01-01

    The range of roaldom walk on Zd in symmetric random environment is investigated. As results, it is proved that the strong law of large numbers for the range of random walk oil Zd in some random environments holds if d > 3, and a weak law of large numbers holds for d = 1.

  15. Random Cell Identifiers Assignment

    Directory of Open Access Journals (Sweden)

    Robert Bestak

    2012-01-01

    Full Text Available Despite integration of advanced functions that enable Femto Access Points (FAPs to be deployed in a plug-and-play manner, the femtocell concept still cause several opened issues to be resolved. One of them represents an assignment of Physical Cell Identifiers (PCIs to FAPs. This paper analyses a random based assignment algorithm in LTE systems operating in diverse femtocell scenarios. The performance of the algorithm is evaluated by comparing the number of confusions for various femtocell densities, PCI ranges and knowledge of vicinity. Simulation results show that better knowledge of vicinity can significantly reduce the number of confusions events.

  16. Random Web Crawls

    OpenAIRE

    Bennouas, Toufik; de Montgolfier, Fabien

    2007-01-01

    International audience This paper proposes a random Web crawl model. A Web crawl is a (biased and partial) image of the Web. This paper deals with the hyperlink structure, i.e. a Web crawl is a graph, whose vertices are the pages and whose edges are the hypertextual links. Of course a Web crawl has a very special structure; we recall some known results about it. We then propose a model generating similar structures. Our model simply simulates a crawling, i.e. builds and crawls the graph at...

  17. Optimized random chemistry

    OpenAIRE

    Buzas, Jeffrey S.; Warrington, Gregory S.

    2013-01-01

    The random chemistry algorithm of Kauffman can be used to determine an unknown subset S of a fixed set V. The algorithm proceeds by zeroing in on S through a succession of nested subsets V=V_0,V_1,...,V_m=S. In Kauffman's original algorithm, the size of each V_i is chosen to be half the size of V_{i-1}. In this paper we determine the optimal sequence of sizes so as to minimize the expected run time of the algorithm.

  18. Can randomization be informative?

    Science.gov (United States)

    Pereira, Carlos A. B.; Campos, Thiago F.; Silva, Gustavo M.; Wechsler, Sergio

    2012-10-01

    In this paper the Pair of Siblings Paradox introduced by Pereira [1] is extended by considering more than two children and more than one child observed for gender. We follow the same lines of Wechsler et al. [2] that generalizes the three prisoners' dilemma, introduced by Gardner [3]. This paper's conjecture is that the Pair of Siblings and the Three Prisoners dilemma are dual paradoxes. Looking at possible likelihoods, the sure (randomized) selection for the former is non informative (informative), the opposite that holds for the latter. This situation is maintained for generalizations. Non informative likelihood here means that prior and posterior are equal.

  19. Random numbers from vacuum fluctuations

    Science.gov (United States)

    Shi, Yicheng; Chng, Brenda; Kurtsiefer, Christian

    2016-07-01

    We implement a quantum random number generator based on a balanced homodyne measurement of vacuum fluctuations of the electromagnetic field. The digitized signal is directly processed with a fast randomness extraction scheme based on a linear feedback shift register. The random bit stream is continuously read in a computer at a rate of about 480 Mbit/s and passes an extended test suite for random numbers.

  20. Random recursive trees and the elephant random walk

    Science.gov (United States)

    Kürsten, Rüdiger

    2016-03-01

    One class of random walks with infinite memory, so-called elephant random walks, are simple models describing anomalous diffusion. We present a surprising connection between these models and bond percolation on random recursive trees. We use a coupling between the two models to translate results from elephant random walks to the percolation process. We calculate, besides other quantities, exact expressions for the first and the second moment of the root cluster size and of the number of nodes in child clusters of the first generation. We further introduce another model, the skew elephant random walk, and calculate the first and second moment of this process.

  1. Precise Asymptotics for Random Matrices and Random Growth Models

    Institute of Scientific and Technical Information of China (English)

    Zhong Gen SU

    2008-01-01

    The author considers the largest eigenvalues of random matrices from Gaussian unitary ensemble and Laguerre unitary ensemble, and the rightmost charge in certain random growth models.We obtain some precise asymptotics results, which are in a sense similar to the precise asymptotics for sums of independent random variables in the context of the law of large numbers and complete convergence. Our proofs depend heavily upon the upper and lower tail estimates for random matrices and random growth models. The Tracy-Widom distribution plays a central role as well.

  2. Random-walk enzymes

    Science.gov (United States)

    Mak, Chi H.; Pham, Phuong; Afif, Samir A.; Goodman, Myron F.

    2015-09-01

    Enzymes that rely on random walk to search for substrate targets in a heterogeneously dispersed medium can leave behind complex spatial profiles of their catalyzed conversions. The catalytic signatures of these random-walk enzymes are the result of two coupled stochastic processes: scanning and catalysis. Here we develop analytical models to understand the conversion profiles produced by these enzymes, comparing an intrusive model, in which scanning and catalysis are tightly coupled, against a loosely coupled passive model. Diagrammatic theory and path-integral solutions of these models revealed clearly distinct predictions. Comparison to experimental data from catalyzed deaminations deposited on single-stranded DNA by the enzyme activation-induced deoxycytidine deaminase (AID) demonstrates that catalysis and diffusion are strongly intertwined, where the chemical conversions give rise to new stochastic trajectories that were absent if the substrate DNA was homogeneous. The C →U deamination profiles in both analytical predictions and experiments exhibit a strong contextual dependence, where the conversion rate of each target site is strongly contingent on the identities of other surrounding targets, with the intrusive model showing an excellent fit to the data. These methods can be applied to deduce sequence-dependent catalytic signatures of other DNA modification enzymes, with potential applications to cancer, gene regulation, and epigenetics.

  3. Random rectangular Graphs

    CERN Document Server

    Estrada, Ernesto

    2015-01-01

    A generalization of the random geometric graph (RGG) model is proposed by considering a set of points uniformly and independently distributed on a rectangle of unit area instead of on a unit square \\left[0,1\\right]^{2}. The topological properties, such as connectivity, average degree, average path length and clustering, of the random rectangular graphs (RRGs) generated by this model are then studied as a function of the rectangle sides lengths a and b=1/a, and the radius r used to connect the nodes. When a=1 we recover the RGG, and when a\\rightarrow\\infty the very elongated rectangle generated resembles a one-dimensional RGG. We provided computational and analytical evidence that the topological properties of the RRG differ significantly from those of the RGG. The connectivity of the RRG depends not only on the number of nodes as in the case of the RGG, but also on the side length of the rectangle. As the rectangle is more elongated the critical radius for connectivity increases following first a power-law an...

  4. Random-walk enzymes.

    Science.gov (United States)

    Mak, Chi H; Pham, Phuong; Afif, Samir A; Goodman, Myron F

    2015-09-01

    Enzymes that rely on random walk to search for substrate targets in a heterogeneously dispersed medium can leave behind complex spatial profiles of their catalyzed conversions. The catalytic signatures of these random-walk enzymes are the result of two coupled stochastic processes: scanning and catalysis. Here we develop analytical models to understand the conversion profiles produced by these enzymes, comparing an intrusive model, in which scanning and catalysis are tightly coupled, against a loosely coupled passive model. Diagrammatic theory and path-integral solutions of these models revealed clearly distinct predictions. Comparison to experimental data from catalyzed deaminations deposited on single-stranded DNA by the enzyme activation-induced deoxycytidine deaminase (AID) demonstrates that catalysis and diffusion are strongly intertwined, where the chemical conversions give rise to new stochastic trajectories that were absent if the substrate DNA was homogeneous. The C→U deamination profiles in both analytical predictions and experiments exhibit a strong contextual dependence, where the conversion rate of each target site is strongly contingent on the identities of other surrounding targets, with the intrusive model showing an excellent fit to the data. These methods can be applied to deduce sequence-dependent catalytic signatures of other DNA modification enzymes, with potential applications to cancer, gene regulation, and epigenetics.

  5. Random Numbers and Quantum Computers

    Science.gov (United States)

    McCartney, Mark; Glass, David

    2002-01-01

    The topic of random numbers is investigated in such a way as to illustrate links between mathematics, physics and computer science. First, the generation of random numbers by a classical computer using the linear congruential generator and logistic map is considered. It is noted that these procedures yield only pseudo-random numbers since…

  6. Strong Decomposition of Random Variables

    DEFF Research Database (Denmark)

    Hoffmann-Jørgensen, Jørgen; Kagan, Abram M.; Pitt, Loren D.;

    2007-01-01

    A random variable X is stongly decomposable if X=Y+Z where Y=Φ(X) and Z=X-Φ(X) are independent non-degenerated random variables (called the components). It is shown that at least one of the components is singular, and we derive a necessary and sufficient condition for strong decomposability...... of a discrete random variable....

  7. Investigating the Randomness of Numbers

    Science.gov (United States)

    Pendleton, Kenn L.

    2009-01-01

    The use of random numbers is pervasive in today's world. Random numbers have practical applications in such far-flung arenas as computer simulations, cryptography, gambling, the legal system, statistical sampling, and even the war on terrorism. Evaluating the randomness of extremely large samples is a complex, intricate process. However, the…

  8. HP-PRRSV challenge of 4 and 10-week-old pigs

    Science.gov (United States)

    In 2006 a unique syndrome was recognized in growing pigs in China with the predominant clinical signs being high fever, anorexia, listlessness, red discoloration of skin, and respiratory distress. The disease had a very high morbidity and mortality rate and became known as porcine high fever disease...

  9. Pilot study of a 10-week multidisciplinary Tai Chi intervention in sedentary obese women.

    NARCIS (Netherlands)

    Dechamps, A.A.; Gatta, B.; Bourdel-Marchasson, I.; Tabarin, A.; Roger, P.

    2009-01-01

    OBJECTIVE: Alternative approaches to weight control and physical activity are increasingly needed. Numerous factors influence weight management, including the choice of physical exercise. No study has previously examined the therapeutic effect of a multidisciplinary weight management program incorpo

  10. Impact of 10-weeks of yoga practice on flexibility and balance of college athletes

    Directory of Open Access Journals (Sweden)

    M Jay Polsgrove

    2016-01-01

    Conclusions: Results suggest that a regular yoga practice may increase the flexibility and balance as well as whole body measures of male college athletes and therefore, may enhance athletic performances that require these characteristics.

  11. Mapping in random-structures

    Energy Technology Data Exchange (ETDEWEB)

    Reidys, C.M.

    1996-06-01

    A mapping in random-structures is defined on the vertices of a generalized hypercube Q{sub {alpha}}{sup n}. A random-structure will consist of (1) a random contact graph and (2) a family of relations imposed on adjacent vertices. The vertex set of a random contact graph will be the set of all coordinates of a vertex P {element_of} Q{sub {alpha}}{sup n}. Its edge will be the union of the edge sets of two random graphs. The first is a random 1-regular graph on 2m vertices (coordinates) and the second is a random graph G{sub p} with p = c{sub 2}/n on all n vertices (coordinates). The structure of the random contact graphs will be investigated and it will be shown that for certain values of m, c{sub 2} the mapping in random-structures allows to search by the set of random-structures. This is applied to mappings in RNA-secondary structures. Also, the results on random-structures might be helpful for designing 3D-folding algorithms for RNA.

  12. Solid-State Random Lasers

    CERN Document Server

    Noginov, Mikhail A

    2005-01-01

    Random lasers are the simplest sources of stimulated emission without cavity, with the feedback provided by scattering in a gain medium. First proposed in the late 60’s, random lasers have grown to a large research field. This book reviews the history and the state of the art of random lasers, provides an outline of the basic models describing their behavior, and describes the recent advances in the field. The major focus of the book is on solid-state random lasers. However, it also briefly describes random lasers based on liquid dyes with scatterers. The chapters of the book are almost independent of each other. So, the scientists or engineers interested in any particular aspect of random lasers can read directly the relevant section. Researchers entering the field of random lasers will find in the book an overview of the field of study. Scientists working in the field can use the book as a reference source.

  13. Randomness Testing of Compressed Data

    CERN Document Server

    Chang, Weiling; Yun, Xiaochun; Wang, Shupeng; Yu, Xiangzhan

    2010-01-01

    Random Number Generators play a critical role in a number of important applications. In practice, statistical testing is employed to gather evidence that a generator indeed produces numbers that appear to be random. In this paper, we reports on the studies that were conducted on the compressed data using 8 compression algorithms or compressors. The test results suggest that the output of compression algorithms or compressors has bad randomness, the compression algorithms or compressors are not suitable as random number generator. We also found that, for the same compression algorithm, there exists positive correlation relationship between compression ratio and randomness, increasing the compression ratio increases randomness of compressed data. As time permits, additional randomness testing efforts will be conducted.

  14. Finite Random Domino Automaton

    CERN Document Server

    Bialecki, Mariusz

    2012-01-01

    Finite version of Random Domino Automaton (FRDA) - recently proposed a toy model of earthquakes - is investigated. Respective set of equations describing stationary state of the FRDA is derived and compared with infinite case. It is shown that for the system of big size, these equations are coincident with RDA equations. We demonstrate a non-existence of exact equations for size N bigger then 4 and propose appropriate approximations, the quality of which is studied in examples obtained within Markov chains framework. We derive several exact formulas describing properties of the automaton, including time aspects. In particular, a way to achieve a quasi-periodic like behaviour of RDA is presented. Thus, based on the same microscopic rule - which produces exponential and inverse-power like distributions - we extend applicability of the model to quasi-periodic phenomena.

  15. Gossip in random networks

    CERN Document Server

    Malarz, K; Szekfu, B; Kulakowski, K

    2006-01-01

    We consider the average probability X of being informed on a gossip in a given social network. The network is modeled within the random graph theory of Erdos and Renyi. In this theory, a network is characterized by two parameters: the size N and the link probability p. Our experimental data suggest three levels of social inclusion of friendship. The critical value p_c, for which half of agents are informed, scales with the system size as N^{-\\gamma} with \\gamma\\approx 0.68. Computer simulations show that the probability X varies with p as a sigmoidal curve. Influence of the correlations between neighbors is also evaluated: with increasing clustering coefficient C, X decreases.

  16. Random Projection Trees Revisited

    CERN Document Server

    Dhesi, Aman

    2010-01-01

    The Random Projection Tree structures proposed in [Freund-Dasgupta STOC08] are space partitioning data structures that automatically adapt to various notions of intrinsic dimensionality of data. We prove new results for both the RPTreeMax and the RPTreeMean data structures. Our result for RPTreeMax gives a near-optimal bound on the number of levels required by this data structure to reduce the size of its cells by a factor $s \\geq 2$. We also prove a packing lemma for this data structure. Our final result shows that low-dimensional manifolds have bounded Local Covariance Dimension. As a consequence we show that RPTreeMean adapts to manifold dimension as well.

  17. Importance of randomness in biological networks: A random matrix analysis

    Indian Academy of Sciences (India)

    Sarika Jalan

    2015-02-01

    Random matrix theory, initially proposed to understand the complex interactions in nuclear spectra, has demonstrated its success in diverse domains of science ranging from quantum chaos to galaxies. We demonstrate the applicability of random matrix theory for networks by providing a new dimension to complex systems research. We show that in spite of huge differences these interaction networks, representing real-world systems, posses from random matrix models, the spectral properties of the underlying matrices of these networks follow random matrix theory bringing them into the same universality class. We further demonstrate the importance of randomness in interactions for deducing crucial properties of the underlying system. This paper provides an overview of the importance of random matrix framework in complex systems research with biological systems as examples.

  18. Random allocation software for parallel group randomized trials

    OpenAIRE

    Saghaei Mahmood

    2004-01-01

    Abstract Background Typically, randomization software should allow users to exert control over the different aspects of randomization including block design, provision of unique identifiers and control over the format and type of program output. While some of these characteristics have been addressed by available software, none of them have all of these capabilities integrated into one package. The main objective of the Random Allocation Software project was to enhance the user's control over...

  19. Random Intercept and Random Slope 2-Level Multilevel Models

    Directory of Open Access Journals (Sweden)

    Rehan Ahmad Khan

    2012-11-01

    Full Text Available Random intercept model and random intercept & random slope model carrying two-levels of hierarchy in the population are presented and compared with the traditional regression approach. The impact of students’ satisfaction on their grade point average (GPA was explored with and without controlling teachers influence. The variation at level-1 can be controlled by introducing the higher levels of hierarchy in the model. The fanny movement of the fitted lines proves variation of student grades around teachers.

  20. A Chinese Chan-Based Mind-Body Intervention Improves Sleep on Patients with Depression: A Randomized Controlled Trial

    Directory of Open Access Journals (Sweden)

    Agnes S. Chan

    2012-01-01

    Full Text Available Sleep disturbance is a common problem associated with depression, and cognitive-behavioral therapy (CBT is a more common behavioral intervention for sleep problems. The present study compares the effect of a newly developed Chinese Chan-based intervention, namely Dejian mind-body intervention (DMBI, with the CBT on improving sleep problems of patients with depression. Seventy-five participants diagnosed with major depressive disorder were randomly assigned to receive 10 weekly sessions of CBT or DMBI, or placed on a waitlist. Measurements included ratings by psychiatrists who were blinded to the experimental design, and a standardized questionnaire on sleep quantity and quality was obtained before and after the 10-week intervention. Results indicated that both the CBT and DMBI groups demonstrated significantly reduced sleep onset latency and wake time after sleep onset (effect size range = 0.46–1.0, P≤0.05 as compared to nonsignificant changes in the waitlist group (P>0.1. Furthermore, the DMBI group, but not the CBT or waitlist groups, demonstrated significantly reduced psychiatrist ratings on overall sleep problems (effect size = 1.0, P=0.00 and improved total sleep time (effect size = 0.8, P=0.05 after treatment. The present findings suggest that a Chinese Chan-based mind-body intervention has positive effects on improving sleep in individuals with depression.

  1. Home-Based Leg Strengthening Exercise Improves Function One Year After Hip Fracture: A Randomized Controlled Study

    Science.gov (United States)

    Mangione, Kathleen K.; Craik, Rebecca L.; Palombaro, Kerstin M.; Tomlinson, Susan S.; Hofmann, Mary T.

    2010-01-01

    Objectives Examine the effectiveness of a short term leg strengthening exercise program compared to attentional control on improving strength, walking abilities, and function one year after hip fracture. Design Randomized controlled pilot study. Setting Interventions occurred in patients’ homes. Participants Community-dwelling older adults (n=26) six months post hip fracture at baseline. Intervention Exercise and control participants received interventions by physical therapists twice weekly for 10 weeks. The exercise group received high intensity leg strengthening exercises. The control group received transcutaneous electrical nerve stimulation and mental imagery. Measurements Isometric force production of lower extremity muscles; usual and fast gait speed, six minute walk (6-MW) distance, modified physical performance test (mPPT), and SF-36 physical function. Results The primary endpoint was at one year post fracture. Isometric force production (pmPPT (pmPPT scores, 0.56 for gait speed, 0.49 for 6-MW, and 0.30 for SF-36 scores. More patients in the exercise group made meaningful changes in gait speed and 6-MW distance than control patients (χ2: p=.004). Conclusion A 10-week home-based progressive resistance exercise program was sufficient to achieve moderate to large effects on physical performance and quality of life and may offer an alternative intervention mode for hip fracture patients who are unable to leave home at 6 months after the fracture. The effects were maintained at 3 months after completion of the training program. PMID:20929467

  2. APPROXIMATION OF RANDOM SUMS OF RANDOM VARIABLES IN INSURANCE

    Directory of Open Access Journals (Sweden)

    Paweł Wlaź

    2014-09-01

    Full Text Available The paper deals with approximations of random sums. By random sum we mean a sum of random number of independent and identically distributed random variables. Distribution of this sum is called a compound distribution. The model is especially important in non-life insurance. There are many methods for approximating compound distributions, one of the most popular one is approximation with shifted gamma distribution. In this work we show an alternative way – using kernel density, Fast Fourier Transform and numerical optimization methods – for finding shifted gamma approximations and show results suggesting its superiority over classical method.

  3. RENEWAL THEOREM FOR (L, 1)-RANDOM WALK IN RANDOM ENVIRONMENT

    Institute of Scientific and Technical Information of China (English)

    洪文明; 孙鸿雁

    2013-01-01

    We consider a random walk on Z in random environment with possible jumps{-L, · · · ,-1, 1}, in the case that the environment{ωi: i∈Z}are i.i.d.. We establish the renewal theorem for the Markov chain of “the environment viewed from the particle” in both annealed probability and quenched probability, which generalize partially the results of Kesten (1977) and Lalley (1986) for the nearest random walk in random environment on Z, respectively. Our method is based on the intrinsic branching structure within the (L, 1)-RWRE formulated in Hong and Wang (2013).

  4. Fractional random walk lattice dynamics

    CERN Document Server

    Michelitsch, Thomas; Riascos, Alejandro Perez; Nowakowski, Andrzeij; Nicolleau, Franck

    2016-01-01

    We analyze time-discrete and continuous `fractional' random walks on undirected regular networks with special focus on cubic periodic lattices in $n=1,2,3,..$ dimensions.The fractional random walk dynamics is governed by a master equation involving {\\it fractional powers of Laplacian matrices $L^{\\frac{\\alpha}{2}}$}where $\\alpha=2$ recovers the normal walk.First we demonstrate thatthe interval $0\\textless{}\\alpha\\leq 2$ is admissible for the fractional random walk. We derive analytical expressions for fractional transition matrix and closely related the average return probabilities. We further obtain thefundamental matrix $Z^{(\\alpha)}$, and the mean relaxation time (Kemeny constant) for the fractional random walk.The representation for the fundamental matrix $Z^{(\\alpha)}$ relates fractional random walks with normal random walks.We show that the fractional transition matrix elements exihibit for large cubic $n$-dimensional lattices a power law decay of an $n$-dimensional infinite spaceRiesz fractional deriva...

  5. Some general random Taylor series

    Institute of Scientific and Technical Information of China (English)

    孙道椿; 余家荣

    1996-01-01

    Kahane has studied the value distribution of Gauss-Taylor series where is a complex Gauss sequence and The value distribution of more general random Taylor series is considered, where {Xn} is a sequence of real or complex random variables of independent, symmetric and equally distributed with finite non-zero fourth moment (the classical Gauss, Steinhaus and Rademacher random variables are special cases of such variables). First a theorem on the growth of characteristic functions is proved by a method which is completely different from Kahane’s. Then it is applied to proving that the range of general random Taylor series is almost surely dense everywhere in the complex plane and that if the random variable is bounded and continuous, the random series surely has no finite Nevanlinna deficient value.

  6. Spatially embedded random networks

    Science.gov (United States)

    Barnett, L.; di Paolo, E.; Bullock, S.

    2007-11-01

    Many real-world networks analyzed in modern network theory have a natural spatial element; e.g., the Internet, social networks, neural networks, etc. Yet, aside from a comparatively small number of somewhat specialized and domain-specific studies, the spatial element is mostly ignored and, in particular, its relation to network structure disregarded. In this paper we introduce a model framework to analyze the mediation of network structure by spatial embedding; specifically, we model connectivity as dependent on the distance between network nodes. Our spatially embedded random networks construction is not primarily intended as an accurate model of any specific class of real-world networks, but rather to gain intuition for the effects of spatial embedding on network structure; nevertheless we are able to demonstrate, in a quite general setting, some constraints of spatial embedding on connectivity such as the effects of spatial symmetry, conditions for scale free degree distributions and the existence of small-world spatial networks. We also derive some standard structural statistics for spatially embedded networks and illustrate the application of our model framework with concrete examples.

  7. Generating random thermal momenta

    CERN Document Server

    Molnar, Denes

    2012-01-01

    Generation of random thermal particle momenta is a basic task in many problems, such as microscopic studies of equilibrium and transport properties of systems, or the conversion of a fluid to particles. In heavy-ion physics, the (in)efficiency of the algorithm matters particularly in hybrid hydrodynamics + hadronic transport calculations. With popular software packages, such as UrQMD 3.3p1 or THERMINATOR, it can still take ten hours to generate particles for a single Pb+Pb "event" at the LHC from fluid dynamics output. Below I describe reasonably efficient simple algorithms using the MPC package, which should help speed momentum generation up by at least one order of magnitude. It is likely that this wheel has been reinvented many times instead of reuse, so there may very well exist older and/or better algorithms that I am not aware of (MPC has been around only since 2000). The main goal here is to encourage practitioners to use available efficient routines, and offer a few practical solutions.

  8. Resistance random access memory

    Directory of Open Access Journals (Sweden)

    Ting-Chang Chang

    2016-06-01

    Full Text Available Non-volatile memory (NVM will play a decisive role in the development of the next-generation of electronic products. Therefore, the development of next-generation NVM is urgent as widely applied flash memory is facing its physical limit. Among various next-generation NVMs, Resistive Random Access Memory (RRAM is a promising candidate for future memory due to its high-efficiency, high-speed and energy-saving characteristics. In recent years, continuous improvement and in-depth investigation in both materials and electrical switching mechanisms have not only lead to a breakthrough in the performance of digital NVM, but also lead to other possible memory functionality. This paper describes new findings and perspectives on various RRAM devices with different laminated structures and materials, and classifies RRAM into four categories according to different resistive switching mechanisms, from which the four elements are (1 anion-type RRAM: redox reaction and migration of oxygen ions, (2 cation-type RRAM: redox reaction and migration of cation ions, (3 carbon-based RRAM: the stretch of CC bond lengths due to oxygen and hydrogen dual ions, (4 oxide-based electrode: oxygen accumulation in oxide-based electrode.

  9. Ferroelectric random access memories.

    Science.gov (United States)

    Ishiwara, Hiroshi

    2012-10-01

    Ferroelectric random access memory (FeRAM) is a nonvolatile memory, in which data are stored using hysteretic P-E (polarization vs. electric field) characteristics in a ferroelectric film. In this review, history and characteristics of FeRAMs are first introduced. It is described that there are two types of FeRAMs, capacitor-type and FET-type, and that only the capacitor-type FeRAM is now commercially available. In chapter 2, properties of ferroelectric films are discussed from a viewpoint of FeRAM application, in which particular attention is paid to those of Pb(Zr,Ti)O3, SrBi2Ta2O9, and BiFeO3. Then, cell structures and operation principle of the capacitor-type FeRAMs are discussed in chapter 3. It is described that the stacked technology of ferroelectric capacitors and development of new materials with large remanent polarization are important for fabricating high-density memories. Finally, in chapter 4, the optimized gate structure in ferroelectric-gate field-effect transistors is discussed and experimental results showing excellent data retention characteristics are presented. PMID:23421123

  10. Random eigenvalue problems revisited

    Indian Academy of Sciences (India)

    S Adhikari

    2006-08-01

    The description of real-life engineering structural systems is associated with some amount of uncertainty in specifying material properties, geometric parameters, boundary conditions and applied loads. In the context of structural dynamics it is necessary to consider random eigenvalue problems in order to account for these uncertainties. Within the engineering literature, current methods to deal with such problems are dominated by approximate perturbation methods. Some exact methods to obtain joint distribution of the natural frequencies are reviewed and their applicability in the context of real-life engineering problems is discussed. A new approach based on an asymptotic approximation of multi-dimensional integrals is proposed. A closed-form expression for general order joint moments of arbitrary numbers of natural frequencies of linear stochastic systems is derived. The proposed method does not employ the ‘small randomness’ assumption usually used in perturbation based methods. Joint distributions of the natural frequencies are investigated using numerical examples and the results are compared with Monte Carlo simulation.

  11. Correlação do volume da vesícula vitelínica obtida por meio da ultrassonografia tridimensional com a idade gestacional entre a 7ª e a 10ª semanas usando o método multiplanar Correlation of yolk sac volume obtained by three-dimensional ultrasonography with the gestational age at 7-10 weeks utilizing the multiplanar method

    Directory of Open Access Journals (Sweden)

    Liliam Cristine Rolo

    2009-12-01

    Full Text Available OBJETIVO: Avaliar a correlação do volume da vesícula vitelínica aferida por meio da ultrassonografia tridimensional com a idade gestacional entre a 7ª e a 10ª semanas. MATERIAIS E MÉTODOS: Realizou-se um estudo do tipo corte transversal envolvendo 72 gestantes normais entre a 7ª e a 10ª semanas de gestação. Para o cálculo do volume da vesícula vitelínica, utilizou-se o método multiplanar com intervalo de 1,0 mm entre os planos. Para o volume da vesícula vitelínica foram determinadas médias, medianas, desvios-padrão e valores máximo e mínimo. Para avaliar a correlação entre o volume da vesícula vitelínica e a idade gestacional, foram criados modelos de regressão, sendo os ajustes realizados pelo coeficiente de determinação (R². RESULTADOS: O volume da vesícula vitelínica (VV mostrou-se fracamente correlacionado com a idade gestacional (IG, melhor representado pela regressão quadrática, representada pela equação: volume VV = 0,9757 - 0,2499 × IG + 0,0172 × IG² (R² = 0,234. O volume médio da vesícula vitelínica variou de 0,07 cm³ (0,02-0,11 a 0,20 cm³ (0,02-0,74 entre a 7ª e a 10ª semanas de gestação, com média de 0,11 cm³ (± 0,10 cm³. CONCLUSÃO: O volume da vesícula vitelínica correlacionou-se fracamente com a idade gestacional.OBJECTIVE: To evaluate the correlation between the yolk sac volume measured by three-dimensional ultrasonography with gestational age at 7-10 weeks. MATERIALS AND METHODS: A cross-sectional study involving 72 healthy pregnant women at 7th-10th gestational weeks. The multiplanar method with 1.0 mm intervals was utilized. Regression models were constructed to analyze the correlation between yolk sac volume and gestational age, adjusted by the determination coefficient (R². Mean, median, standard deviation, maximum and minimum values for yolk sac volume were calculated for each gestational age. RESULTS: A poor correlation was observed between yolk sac volume (YSV and

  12. Random walkers versus random crowds: diffusion of large matrices

    OpenAIRE

    Gudowska-Nowak, Ewa; Janik, Romuald J.; Jurkiewicz, Jerzy; Nowak, Maciej A.; Wieczorek, Waldemar

    2006-01-01

    We briefly review the random matrix theory for large N by N matrices viewed as free random variables in a context of stochastic diffusion. We establish a surprising link between the spectral properties of matrix-valued multiplicative diffusion processes for hermitian and unitary ensembles.

  13. Random allocation software for parallel group randomized trials

    Directory of Open Access Journals (Sweden)

    Saghaei Mahmood

    2004-11-01

    Full Text Available Abstract Background Typically, randomization software should allow users to exert control over the different aspects of randomization including block design, provision of unique identifiers and control over the format and type of program output. While some of these characteristics have been addressed by available software, none of them have all of these capabilities integrated into one package. The main objective of the Random Allocation Software project was to enhance the user's control over different aspects of randomization in parallel group trials, including output type and format, structure and ordering of generated unique identifiers and enabling users to specify group names for more than two groups. Results The program has different settings for: simple and blocked randomizations; length, format and ordering of generated unique identifiers; type and format of program output; and saving sessions for future use. A formatted random list generated by this program can be used directly (without further formatting by the coordinator of the research team to prepare and encode different drugs or instruments necessary for the parallel group trial. Conclusions Random Allocation Software enables users to control different attributes of the random allocation sequence and produce qualified lists for parallel group trials.

  14. Local Interaction on Random Graphs

    Directory of Open Access Journals (Sweden)

    Hans Haller

    2010-08-01

    Full Text Available We analyze dynamic local interaction in population games where the local interaction structure (modeled as a graph can change over time: A stochastic process generates a random sequence of graphs. This contrasts with models where the initial interaction structure (represented by a deterministic graph or the realization of a random graph cannot change over time.

  15. Markov Random Field Surface Reconstruction

    DEFF Research Database (Denmark)

    Paulsen, Rasmus Reinhold; Bærentzen, Jakob Andreas; Larsen, Rasmus

    2010-01-01

    A method for implicit surface reconstruction is proposed. The novelty in this paper is the adaption of Markov Random Field regularization of a distance field. The Markov Random Field formulation allows us to integrate both knowledge about the type of surface we wish to reconstruct (the prior...

  16. Quantum to Classical Randomness Extractors

    CERN Document Server

    Berta, Mario; Wehner, Stephanie

    2011-01-01

    Even though randomness is an essential resource for many information processing tasks, it is not easily found in nature. The goal of randomness extraction is to distill (almost) perfect randomness from a weak source of randomness. When the source yields a classical string X, many extractor constructions are known. Yet, when considering a physical randomness source, X is itself ultimately the result of a measurement on an underlying quantum system. When characterizing the power of a source to supply randomness it is hence a natural question to ask, how much classical randomness we can extract from a quantum state. To tackle this question we here take on the study of quantum-to-classical randomness extractors (QC-extractors). We provide constructions of QC-extractors based on measurements in a full set of mutually unbiased bases (MUBs), and certain single qubit measurements. As the first application, we show that any QC-extractor gives rise to entropic uncertainty relations with respect to quantum side informat...

  17. Ticks of a Random clock

    Science.gov (United States)

    Jung, P.; Talkner, P.

    2010-09-01

    A simple way to convert a purely random sequence of events into a signal with a strong periodic component is proposed. The signal consists of those instants of time at which the length of the random sequence exceeds an integer multiple of a given number. The larger this number the more pronounced the periodic behavior becomes.

  18. WEAK UNCORRELATEDNESS OF RANDOM VARIABLES

    Institute of Scientific and Technical Information of China (English)

    Sofiya Ostrovska

    2006-01-01

    New measures of independence for n random variables, based on their moments, are studied. A scale of degrees of independence for random variables which starts with uncorrelatedness (for n = 2) and finishes at independence is constructed. The scale provides a countable linearly ordered set of measures of independence.

  19. Fields on a random lattice

    International Nuclear Information System (INIS)

    We review the formulation of field theory and statistical mechanics on a Poissonian random lattice. Topics discussed include random geometry, the construction of field equations for arbitrary spin, the free field spectrum and the question of localization illustrated in the one dimensional case

  20. Levy flights and random searches

    International Nuclear Information System (INIS)

    In this work we discuss some recent contributions to the random search problem. Our analysis includes superdiffusive Levy processes and correlated random walks in several regimes of target site density, mobility and revisitability. We present results in the context of mean-field-like and closed-form average calculations, as well as numerical simulations. We then consider random searches performed in regular lattices and lattices with defects, and we discuss a necessary criterion for distinguishing true superdiffusion from correlated random walk processes. We invoke energy considerations in relation to critical survival states on the edge of extinction, and we analyze the emergence of Levy behavior in deterministic search walks. Finally, we comment on the random search problem in the context of biological foraging.

  1. Delocalization for Random Landau Hamiltonians with Unbounded Random Variables

    CERN Document Server

    Germinet, François; Mandy, Benoît

    2009-01-01

    In this note we prove the existence of a localization/delocalization transition for Landau Hamiltonians randomly perturbed by an electric potential with unbounded amplitude. In particular, with probability one, no Landau gaps survive as the random potential is turned on, the gaps close, filling up partly with localized states. A minimal rate of transport is exhibited in the region of delocalization. To do so, we exploit the a priori quantization of the Hall conductance and extend recent Wegner estimates to the case of unbounded random variables.

  2. Preventive effect of eccentric training on acute hamstring injuries in men's soccer: A cluster-randomized controlled trial

    DEFF Research Database (Denmark)

    Petersen, Jesper; Thorborg, Kristian; Nielsen, Michael Bachmann;

    2011-01-01

    hamstring exercise on the rate of acute hamstring injuries in male soccer players. Study Design: Randomized controlled trial; Level of evidence, 1. Methods: Fifty Danish male professional and amateur soccer teams (942 players) were allocated to an intervention group (461 players) or a control group (481...... players). Players in the intervention group conducted a 10-week progressive eccentric training program followed by a weekly seasonal program, whereas players in the control group followed their usual training program. The main outcome measures were numbers of overall, new, and recurrent acute hamstring...... injuries during 1 full soccer season. Results: Fifty-two acute hamstring injuries in the control group compared with 15 injuries in the intervention group were registered. Comparing intervention versus the control group, overall acute hamstring injury rates per 100 player seasons were 3.8 versus 13...

  3. Randomized Consensus Processing over Random Graphs: Independence and Convergence

    CERN Document Server

    Shi, Guodong

    2011-01-01

    Various consensus algorithms over random networks have been investigated in the literature. In this paper, we focus on the role that randomized individual decision-making plays to consensus seeking under stochastic communications. At each time step, each node will independently choose to follow the consensus algorithm, or to stick to current state by a simple Bernoulli trial with time-dependent success probabilities. This node decision strategy characterizes the random node-failures on a communication networks, or a biased opinion selection in the belief evolution over social networks. Connectivity-independent and arc-independent graphs are defined, respectively, to capture the fundamental nature of random network processes with regard to the convergence of the consensus algorithms. A series of sufficient and/or necessary conditions are given on the success probability sequence for the network to reach a global consensus with probability one under different stochastic connectivity assumptions, by which a comp...

  4. True Randomness from Big Data

    Science.gov (United States)

    Papakonstantinou, Periklis A.; Woodruff, David P.; Yang, Guang

    2016-09-01

    Generating random bits is a difficult task, which is important for physical systems simulation, cryptography, and many applications that rely on high-quality random bits. Our contribution is to show how to generate provably random bits from uncertain events whose outcomes are routinely recorded in the form of massive data sets. These include scientific data sets, such as in astronomics, genomics, as well as data produced by individuals, such as internet search logs, sensor networks, and social network feeds. We view the generation of such data as the sampling process from a big source, which is a random variable of size at least a few gigabytes. Our view initiates the study of big sources in the randomness extraction literature. Previous approaches for big sources rely on statistical assumptions about the samples. We introduce a general method that provably extracts almost-uniform random bits from big sources and extensively validate it empirically on real data sets. The experimental findings indicate that our method is efficient enough to handle large enough sources, while previous extractor constructions are not efficient enough to be practical. Quality-wise, our method at least matches quantum randomness expanders and classical world empirical extractors as measured by standardized tests.

  5. An introduction to random sets

    CERN Document Server

    Nguyen, Hung T

    2006-01-01

    The study of random sets is a large and rapidly growing area with connections to many areas of mathematics and applications in widely varying disciplines, from economics and decision theory to biostatistics and image analysis. The drawback to such diversity is that the research reports are scattered throughout the literature, with the result that in science and engineering, and even in the statistics community, the topic is not well known and much of the enormous potential of random sets remains untapped.An Introduction to Random Sets provides a friendly but solid initiation into the theory of random sets. It builds the foundation for studying random set data, which, viewed as imprecise or incomplete observations, are ubiquitous in today''s technological society. The author, widely known for his best-selling A First Course in Fuzzy Logic text as well as his pioneering work in random sets, explores motivations, such as coarse data analysis and uncertainty analysis in intelligent systems, for studying random s...

  6. True Randomness from Big Data

    Science.gov (United States)

    Papakonstantinou, Periklis A.; Woodruff, David P.; Yang, Guang

    2016-01-01

    Generating random bits is a difficult task, which is important for physical systems simulation, cryptography, and many applications that rely on high-quality random bits. Our contribution is to show how to generate provably random bits from uncertain events whose outcomes are routinely recorded in the form of massive data sets. These include scientific data sets, such as in astronomics, genomics, as well as data produced by individuals, such as internet search logs, sensor networks, and social network feeds. We view the generation of such data as the sampling process from a big source, which is a random variable of size at least a few gigabytes. Our view initiates the study of big sources in the randomness extraction literature. Previous approaches for big sources rely on statistical assumptions about the samples. We introduce a general method that provably extracts almost-uniform random bits from big sources and extensively validate it empirically on real data sets. The experimental findings indicate that our method is efficient enough to handle large enough sources, while previous extractor constructions are not efficient enough to be practical. Quality-wise, our method at least matches quantum randomness expanders and classical world empirical extractors as measured by standardized tests. PMID:27666514

  7. RANDOM, Random Number Generator with Large Cycle Length

    International Nuclear Information System (INIS)

    1 - Description of problem or function: RANDOM is a portable pseudo- random number generator with a cycle length exceeding 2.78 * 1013. 2 - Method of solution: Three simple multiplicative congruential generators are used. Each one uses a prime number for its modulus and a primitive root for its multiplier. 3 - Restrictions on the complexity of the problem: Integer arithmetic up to 30323 is required

  8. Spectral Properties of Random Reactance Networks and Random Matrix Pencils

    OpenAIRE

    Fyodorov, Yan V

    1999-01-01

    Our goal is to study statistical properies of "dielectric resonances" which are poles of conductance of a large random $LC$ network. Such poles are a particular example of eigenvalues $\\lambda_n$ of matrix pencils ${\\bf H}-\\lambda {\\bf W}$, with ${\\bf W}$ being positive definite matrix and ${\\bf H}$ a random real symmetric one. We first consider spectra of matrix pencils with independent, identically distributed entries of ${\\bf H}$. Then we concentrate on an infinite-range ("full-connectivit...

  9. CONCEPTUAL ANALYSIS AND RANDOM ATTRACTOR FOR DISSIPATIVE RANDOM DYNAMICAL SYSTEMS

    Institute of Scientific and Technical Information of China (English)

    Li Yuhong; Zdzistaw Brze(z)niak; Zhou Jianzhong

    2008-01-01

    The aim of this work is to understand better the long time behaviour of asymptotically compact random dynamical systems (RDS), which can be generated by solutions of some stochastic partial differential equations on unbounded domains. The conceptual analysis for the long time behavior of RDS will be done through some examples. An application of those analysis will be demonstrated through the proof of the existence of random attractors for asymptotically compact dissipative RDS.

  10. The efficacy of extended-release levomilnacipran in moderate to severe major depressive disorder: secondary and post-hoc analyses from a randomized, double-blind, placebo-controlled study

    OpenAIRE

    Montgomery, Stuart A.; Mansuy, Lucilla; Ruth, Adam C.; Li, Dayong; Gommoll, Carl

    2013-01-01

    Levomilnacipran (1S, 2R-milnacipran) is a potent and selective serotonin and norepinephrine reuptake inhibitor that is Food and Drug Administration approved for once-daily treatment of major depressive disorder in adults. Secondary and post-hoc analyses were carried out on data from a positive 10-week, randomized, double-blind, placebo-controlled, parallel-group, multicenter, proof-of-concept trial (EudraCT Number: 2006-002404-34) on 75 or 100 mg/day levomilnacipran extended release (ER). Inc...

  11. Symmetrization of binary random variables

    OpenAIRE

    Kagan, Abram; Mallows, Colin L.; Shepp, Larry A.; Vanderbei, Robert J.; Vardi, Yehuda

    1999-01-01

    A random variable [math] is called an independent symmetrizer of a given random variable [math] if (a) it is independent of [math] and (b) the distribution of [math] is symmetric about [math] . In cases where the distribution of [math] is symmetric about its mean, it is easy to see that the constant random variable [math] is a minimum-variance independent symmetrizer. Taking [math] to have the same distribution as [math] clearly produces a symmetric sum, but it may not be of minimum variance....

  12. Random processes in nuclear reactors

    CERN Document Server

    Williams, M M R

    1974-01-01

    Random Processes in Nuclear Reactors describes the problems that a nuclear engineer may meet which involve random fluctuations and sets out in detail how they may be interpreted in terms of various models of the reactor system. Chapters set out to discuss topics on the origins of random processes and sources; the general technique to zero-power problems and bring out the basic effect of fission, and fluctuations in the lifetime of neutrons, on the measured response; the interpretation of power reactor noise; and associated problems connected with mechanical, hydraulic and thermal noise sources

  13. Covariate-based constrained randomization of group-randomized trials.

    Science.gov (United States)

    Moulton, Lawrence H

    2004-01-01

    Group-randomized study designs are useful when individually randomized designs are either not possible, or will not be able to estimate the parameters of interest. Blocked and/or stratified (for example, pair-matched) designs have been used, and their properties statistically evaluated by many researchers. Group-randomized trials often have small numbers of experimental units, and strong, geographically induced between-unit correlation, which increase the chance of obtaining a "bad" randomization outcome. This article describes a procedure--random selection from a list of acceptable allocations--to allocate treatment conditions in a way that ensures balance on relevant covariates. Numerous individual- and group-level covariates can be balanced using exact or caliper criteria. Simulation results indicate that this method has good frequency properties, but some care may be needed not to overly constrain the randomization. There is a trade-off between achieving good balance through a highly constrained design, and jeopardizing the appearance of impartiality of the investigator and potentially departing from the nominal Type I error. PMID:16279255

  14. Acupuncture Antiarrhythmic Effects on Drug Refractory Persistent Atrial Fibrillation: Study Protocol for a Randomized, Controlled Trial

    Directory of Open Access Journals (Sweden)

    Jimin Park

    2015-01-01

    Full Text Available Background. Atrial fibrillation (AF is the most common form of arrhythmia. Several trials have suggested that acupuncture may prevent AF. However, the efficacy of acupuncture for AF prevention has not been well investigated. Therefore, we designed a prospective, two-parallel-armed, participant and assessor blinded, randomized, sham-controlled clinical trial to investigate acupuncture in persistent AF (ACU-AF. Methods. A total of 80 participants will be randomly assigned to active acupuncture or sham acupuncture groups in a 1 : 1 ratio. Both groups will take the same antiarrhythmic medication during the study period. Patients will receive 10 sessions of acupuncture treatment once a week for 10 weeks. The primary endpoint is AF recurrence rate. Secondary endpoints are left atrium (LA and left atrial appendage (LAA changes in function and volume, and inflammatory biomarker changes. Ethics. This study protocol was approved by the institutional review boards (IRBs of Kyung Hee University Hospital (number 1335-04. This trial is registered with clinicaltrials.gov NCT02110537.

  15. Random Distances Associated with Rhombuses

    CERN Document Server

    Zhuang, Yanyan

    2011-01-01

    Parallelograms are one of the basic building blocks in two-dimensional tiling. They have important applications in a wide variety of science and engineering fields, such as wireless communication networks, urban transportation, operations research, etc. Different from rectangles and squares, the coordinates of a random point in parallelograms are no longer independent. As a case study of parallelograms, the explicit probability density functions of the random Euclidean distances associated with rhombuses are given in this report, when both endpoints are randomly distributed in 1) the same rhombus, 2) two parallel rhombuses sharing a side, and 3) two rhombuses having a common diagonal, respectively. The accuracy of the distance distribution functions is verified by simulation, and the correctness is validated by a recursion and a probabilistic sum. The first two statistical moments of the random distances, and the polynomial fit of the density functions are also given in this report for practical uses.

  16. Quantum entanglement from random measurements

    Science.gov (United States)

    Tran, Minh Cong; Dakić, Borivoje; Arnault, François; Laskowski, Wiesław; Paterek, Tomasz

    2015-11-01

    We show that the expectation value of squared correlations measured along random local directions is an identifier of quantum entanglement in pure states, which can be directly experimentally assessed if two copies of the state are available. Entanglement can therefore be detected by parties who do not share a common reference frame and whose local reference frames, such as polarizers or Stern-Gerlach magnets, remain unknown. Furthermore, we also show that in every experimental run, access to only one qubit from the macroscopic reference is sufficient to identify entanglement, violate a Bell inequality, and, in fact, observe all phenomena observable with macroscopic references. Finally, we provide a state-independent entanglement witness solely in terms of random correlations and emphasize how data gathered for a single random measurement setting per party reliably detects entanglement. This is only possible due to utilized randomness and should find practical applications in experimental confirmation of multiphoton entanglement or space experiments.

  17. Solid-Phase Random Glycosylation

    DEFF Research Database (Denmark)

    Agoston, K.; Kröger, Lars; Dekany, Gyula;

    2009-01-01

    Two different approaches were employed to study solid phase random glycosylations to obtain oligosaccharide libraries. In approach I, Wang resin esters were attached to the acceptors structures. Following their glycosylation and resin cleavage, the peracetylated components of the oligosaccharide...

  18. Random walks on reductive groups

    CERN Document Server

    Benoist, Yves

    2016-01-01

    The classical theory of Random Walks describes the asymptotic behavior of sums of independent identically distributed random real variables. This book explains the generalization of this theory to products of independent identically distributed random matrices with real coefficients. Under the assumption that the action of the matrices is semisimple – or, equivalently, that the Zariski closure of the group generated by these matrices is reductive - and under suitable moment assumptions, it is shown that the norm of the products of such random matrices satisfies a number of classical probabilistic laws. This book includes necessary background on the theory of reductive algebraic groups, probability theory and operator theory, thereby providing a modern introduction to the topic.

  19. Random Matrices, Boundaries and Branes

    CERN Document Server

    Niedner, Benjamin

    2016-01-01

    This thesis is devoted to the application of random matrix theory to the study of random surfaces, both discrete and continuous; special emphasis is placed on surface boundaries and the associated boundary conditions in this formalism. In particular, using a multi-matrix integral with permutation symmetry, we are able to calculate the partition function of the Potts model on a random planar lattice with various boundary conditions imposed. We proceed to investigate the correspondence between the critical points in the phase diagram of this model and two-dimensional Liouville theory coupled to conformal field theories with global $\\mathcal{W}$-symmetry. In this context, each boundary condition can be interpreted as the description of a brane in a family of bosonic string backgrounds. This investigation suggests that a spectrum of initially distinct boundary conditions of a given system may become degenerate when the latter is placed on a random surface of bounded genus, effectively leaving a smaller set of ind...

  20. Quantifying randomness in real networks.

    Science.gov (United States)

    Orsini, Chiara; Dankulov, Marija M; Colomer-de-Simón, Pol; Jamakovic, Almerima; Mahadevan, Priya; Vahdat, Amin; Bassler, Kevin E; Toroczkai, Zoltán; Boguñá, Marián; Caldarelli, Guido; Fortunato, Santo; Krioukov, Dmitri

    2015-10-20

    Represented as graphs, real networks are intricate combinations of order and disorder. Fixing some of the structural properties of network models to their values observed in real networks, many other properties appear as statistical consequences of these fixed observables, plus randomness in other respects. Here we employ the dk-series, a complete set of basic characteristics of the network structure, to study the statistical dependencies between different network properties. We consider six real networks--the Internet, US airport network, human protein interactions, technosocial web of trust, English word network, and an fMRI map of the human brain--and find that many important local and global structural properties of these networks are closely reproduced by dk-random graphs whose degree distributions, degree correlations and clustering are as in the corresponding real network. We discuss important conceptual, methodological, and practical implications of this evaluation of network randomness, and release software to generate dk-random graphs.

  1. Lowest Eigenvalues of Random Hamiltonians

    CERN Document Server

    Shen, J J; Arima, A; Yoshinaga, N

    2008-01-01

    In this paper we present results of the lowest eigenvalues of random Hamiltonians for both fermion and boson systems. We show that an empirical formula of evaluating the lowest eigenvalues of random Hamiltonians in terms of energy centroids and widths of eigenvalues are applicable to many different systems (except for $d$ boson systems). We improve the accuracy of the formula by adding moments higher than two. We suggest another new formula to evaluate the lowest eigenvalues for random matrices with large dimensions (20-5000). These empirical formulas are shown to be applicable not only to the evaluation of the lowest energy but also to the evaluation of excited energies of systems under random two-body interactions.

  2. A Randomized, Controlled Trial of the Impact of Alternative Dosing Schedules on the Immune Response to Human Rotavirus Vaccine in Rural Ghanaian Infants

    Science.gov (United States)

    Armah, George; Lewis, Kristen D. C.; Cortese, Margaret M.; Parashar, Umesh D.; Ansah, Akosua; Gazley, Lauren; Victor, John C.; McNeal, Monica M.; Binka, Fred; Steele, A. Duncan

    2016-01-01

    Background. The recommended schedule for receipt of 2-dose human rotavirus vaccine (HRV) coincides with receipt of the first and second doses of diphtheria, pertussis, and tetanus vaccine (ie, 6 and 10 weeks of age, respectively). Alternative schedules and additional doses of HRV have been proposed and may improve vaccine performance in low-income countries. Methods. In this randomized trial in rural Ghana, HRV was administered at ages 6 and 10 weeks (group 1), 10 and 14 weeks (group 2), or 6, 10, and 14 weeks (group 3). We compared serum antirotavirus immunoglobulin A (IgA) seroconversion (≥20 U/mL) and geometric mean concentrations (GMCs) between group 1 and groups 2 and 3. Results. Ninety-three percent of participants (424 of 456) completed the study per protocol. In groups 1, 2, and 3, the IgA seroconversion frequencies among participants with IgA levels of <20 U/mL at baseline were 28.9%, 37.4%, and 43.4%, respectively (group 1 vs group 3, P = .014; group 1 vs group 2, P = .163). Postvaccination IgA GMCs were 22.1 U/mL, 26.5 U/mL, and 32.6 U/mL in groups 1, 2, and 3, respectively (group 1 vs group 3, P = .038; group 1 vs group 2, P = .304). Conclusions. A third dose of HRV resulted in increased seroconversion frequencies and GMCs, compared with 2 doses administered at 6 and 10 weeks of age. Since there is no correlate of protection, a postmarketing effectiveness study is required to determine whether the improvement in immune response translates into a public health benefit in low-income countries. Clinical Trials Registration. NCT015751. PMID:26823335

  3. Ten weeks of physical-cognitive-mindfulness training reduces fear-avoidance beliefs about work-related activity: Randomized controlled trial.

    Science.gov (United States)

    Jay, Kenneth; Brandt, Mikkel; Jakobsen, Markus Due; Sundstrup, Emil; Berthelsen, Kasper Gymoese; Schraefel, Mc; Sjøgaard, Gisela; Andersen, Lars L

    2016-08-01

    People with chronic musculoskeletal pain often experience pain-related fear of movement and avoidance behavior. The Fear-Avoidance model proposes a possible mechanism at least partly explaining the development and maintenance of chronic pain. People who interpret pain during movement as being potentially harmful to the organism may initiate a vicious behavioral cycle by generating pain-related fear of movement accompanied by avoidance behavior and hyper-vigilance.This study investigates whether an individually adapted multifactorial approach comprised of biopsychosocial elements, with a focus on physical exercise, mindfulness, and education on pain and behavior, can decrease work-related fear-avoidance beliefs.As part of a large scale 10-week worksite randomized controlled intervention trial focusing on company initiatives to combat work-related musculoskeletal pain and stress, we evaluated fear-avoidance behavior in 112 female laboratory technicians with chronic neck, shoulder, upper back, lower back, elbow, and hand/wrist pain using the Fear-Avoidance Beliefs Questionnaire at baseline, before group allocation, and again at the post intervention follow-up 10 weeks later.A significant group by time interaction was observed (P avoidance beliefs. The between-group difference at follow-up was -2.2 (-4.0 to -0.5), corresponding to a small to medium effect size (Cohen's d = 0.30).Our study shows that work-related, but not leisure time activity-related, fear-avoidance beliefs, as assessed by the Fear-avoidance Beliefs Questionnaire, can be significantly reduced by 10 weeks of physical-cognitive-mindfulness training in female laboratory technicians with chronic pain.

  4. Snakes and perturbed random walks

    CERN Document Server

    Basak, Gopal

    2011-01-01

    In this paper we study some properties of random walks perturbed at extrema, which are generalizations of the walks considered e.g., in Davis (1999). This process can also be viewed as a version of {\\em excited random walk}, studied recently by many authors. We obtain a few properties related to the range of the process with infinite memory. We also prove the Strong law, Central Limit Theorem, and the criterion for the recurrence of the perturbed walk with finite memory.

  5. Enactive metaphoric approaches to randomness

    OpenAIRE

    Díaz-Rojas, Daniela; Soto-Andrade, Jorge

    2015-01-01

    Our work aims at developing means to facilitating the access to stochastic thinking, especially for non-mathematically oriented learners. To this end, we draw on metaphoric and enactive approaches to the teaching and learning of randomness. More precisely, we report on a challenging didactical situation implemented in various classrooms, with students and prospective and practicing teachers, concerning problem posing and solving in the context of randomness that is approached through enactive...

  6. Optimal Contracts with Random Auditing

    OpenAIRE

    Andrei Barbos

    2015-01-01

    In this paper we study an optimal contract problem under moral hazard in a principal-agent framework where contracts are implemented through random auditing. This monitoring instrument reveals the precise action taken by the agent with some nondegenerate probability r, and otherwise reveals no information. We characterize optimal contracts with random perfect monitoring under several information structures that allow for moral hazard and adverse selection. We evaluate the effect of the intens...

  7. The weighted random graph model

    OpenAIRE

    Garlaschelli, Diego

    2009-01-01

    We introduce the weighted random graph (WRG) model, which represents the weighted counterpart of the Erdos-Renyi random graph and provides fundamental insights into more complicated weighted networks. We find analytically that the WRG is characterized by a geometric weight distribution, a binomial degree distribution and a negative binomial strength distribution. We also characterize exactly the percolation phase transitions associated with edge removal and with the appearance of weighted sub...

  8. Staggered chiral random matrix theory

    International Nuclear Information System (INIS)

    We present a random matrix theory for the staggered lattice QCD Dirac operator. The staggered random matrix theory is equivalent to the zero-momentum limit of the staggered chiral Lagrangian and includes all taste breaking terms at their leading order. This is an extension of previous work which only included some of the taste breaking terms. We will also present some results for the taste breaking contributions to the partition function and the Dirac eigenvalues.

  9. On Conditional Simple Random Sample

    OpenAIRE

    Wywiał, Janusz L.

    2014-01-01

    Estimation of the population average in a finite and fixed population on the basis of the conditional simple random sampling design dependent on order statistics of the auxiliary variable is studied. The sampling scheme implementing the sampling design is proposed. The inclusion probabilities are derived. The well known Horvitz-Thompson statistic under the conditional simple random sampling designs is considered as the estimator of population mean. Moreover, it was shown that the Horvitz-Thom...

  10. A local limit theorem for random walks in random scenery and on randomly oriented lattices

    CERN Document Server

    Castell, Fabienne; Pène, Françoise; Schapira, Bruno

    2010-01-01

    Random walks in random scenery are processes defined by $Z_n:=\\sum_{k=1}^n\\xi_{X_1+...+X_k}$, where $(X_k,k\\ge 1)$ and $(\\xi_y,y\\in\\mathbb Z)$ are two independent sequences of i.i.d. random variables. We assume here that their distributions belong to the normal domain of attraction of stable laws with index $\\alpha\\in (0,2]$ and $\\beta\\in (0,2]$ respectively. These processes were first studied by H. Kesten and F. Spitzer, who proved the convergence in distribution when $\\alpha\

  11. An introduction to random interlacements

    CERN Document Server

    Drewitz, Alexander; Sapozhnikov, Artëm

    2014-01-01

    This book gives a self-contained introduction to the theory of random interlacements. The intended reader of the book is a graduate student with a background in probability theory who wants to learn about the fundamental results and methods of this rapidly emerging field of research. The model was introduced by Sznitman in 2007 in order to describe the local picture left by the trace of a random walk on a large discrete torus when it runs up to times proportional to the volume of the torus. Random interlacements is a new percolation model on the d-dimensional lattice. The main results covered by the book include the full proof of the local convergence of random walk trace on the torus to random interlacements and the full proof of the percolation phase transition of the vacant set of random interlacements in all dimensions. The reader will become familiar with the techniques relevant to working with the underlying Poisson Process and the method of multi-scale renormalization, which helps in overcoming the ch...

  12. Random walk of passive tracers among randomly moving obstacles

    CERN Document Server

    Gori, Matteo; Floriani, Elena; Nardecchia, Ilaria; Pettini, Marco

    2016-01-01

    Background: This study is mainly motivated by the need of understanding how the diffusion behaviour of a biomolecule (or even of a larger object) is affected by other moving macromolecules, organelles, and so on, inside a living cell, whence the possibility of understanding whether or not a randomly walking biomolecule is also subject to a long-range force field driving it to its target. Method: By means of the Continuous Time Random Walk (CTRW) technique the topic of random walk in random environment is here considered in the case of a passively diffusing particle in a crowded environment made of randomly moving and interacting obstacles. Results: The relevant physical quantity which is worked out is the diffusion cofficient of the passive tracer which is computed as a function of the average inter-obstacles distance. Coclusions: The results reported here suggest that if a biomolecule, let us call it a test molecule, moves towards its target in the presence of other independently interacting molecules, its m...

  13. Renewal theorems for random walks in random scenery

    CERN Document Server

    Guillotin-Plantard, Nadine

    2011-01-01

    Random walks in random scenery are processes defined by $Z_n:=\\sum_{k=1}^n\\xi_{X_1+...+X_k}$, where $(X_k,k\\ge 1)$ and $(\\xi_y,y\\in\\mathbb Z)$ are two independent sequences of i.i.d. random variables. We suppose that the distributions of $X_1$ and $\\xi_0$ belong to the normal domain of attraction of strictly stable distributions with index $\\alpha\\in[1,2]$ and $\\beta\\in(0,2)$ respectively. We are interested in the asymptotic behaviour as $|a|$ goes to infinity of quantities of the form $\\sum_{n\\ge 1}{\\mathbb E}[h(Z_n-a)]$ (when $(Z_n)_n$ is transient) or $\\sum_{n\\ge 1}{\\mathbb E}[h(Z_n)-h(Z_n-a)]$ (when $(Z_n)_n$ is recurrent) where $h$ is some complex-valued function defined on $\\mathbb{R}$ or $\\mathbb{Z}$.

  14. The parabolic Anderson model random walk in random potential

    CERN Document Server

    König, Wolfgang

    2016-01-01

    This is a comprehensive survey on the research on the parabolic Anderson model – the heat equation with random potential or the random walk in random potential – of the years 1990 – 2015. The investigation of this model requires a combination of tools from probability (large deviations, extreme-value theory, e.g.) and analysis (spectral theory for the Laplace operator with potential, variational analysis, e.g.). We explain the background, the applications, the questions and the connections with other models and formulate the most relevant results on the long-time behavior of the solution, like quenched and annealed asymptotics for the total mass, intermittency, confinement and concentration properties and mass flow. Furthermore, we explain the most successful proof methods and give a list of open research problems. Proofs are not detailed, but concisely outlined and commented; the formulations of some theorems are slightly simplified for better comprehension.

  15. Virial expansion for almost diagonal random matrices

    Science.gov (United States)

    Yevtushenko, Oleg; Kravtsov, Vladimir E.

    2003-08-01

    Energy level statistics of Hermitian random matrices hat H with Gaussian independent random entries Higeqj is studied for a generic ensemble of almost diagonal random matrices with langle|Hii|2rangle ~ 1 and langle|Hi\

  16. Advances in randomized parallel computing

    CERN Document Server

    Rajasekaran, Sanguthevar

    1999-01-01

    The technique of randomization has been employed to solve numerous prob­ lems of computing both sequentially and in parallel. Examples of randomized algorithms that are asymptotically better than their deterministic counterparts in solving various fundamental problems abound. Randomized algorithms have the advantages of simplicity and better performance both in theory and often in practice. This book is a collection of articles written by renowned experts in the area of randomized parallel computing. A brief introduction to randomized algorithms In the aflalysis of algorithms, at least three different measures of performance can be used: the best case, the worst case, and the average case. Often, the average case run time of an algorithm is much smaller than the worst case. 2 For instance, the worst case run time of Hoare's quicksort is O(n ), whereas its average case run time is only O( n log n). The average case analysis is conducted with an assumption on the input space. The assumption made to arrive at t...

  17. Cover times of random searches

    Science.gov (United States)

    Chupeau, Marie; Bénichou, Olivier; Voituriez, Raphaël

    2015-10-01

    How long must one undertake a random search to visit all sites of a given domain? This time, known as the cover time, is a key observable to quantify the efficiency of exhaustive searches, which require a complete exploration of an area and not only the discovery of a single target. Examples range from immune-system cells chasing pathogens to animals harvesting resources, from robotic exploration for cleaning or demining to the task of improving search algorithms. Despite its broad relevance, the cover time has remained elusive and so far explicit results have been scarce and mostly limited to regular random walks. Here we determine the full distribution of the cover time for a broad range of random search processes, including Lévy strategies, intermittent strategies, persistent random walks and random walks on complex networks, and reveal its universal features. We show that for all these examples the mean cover time can be minimized, and that the corresponding optimal strategies also minimize the mean search time for a single target, unambiguously pointing towards their robustness.

  18. Exponential-family Random Network Models

    OpenAIRE

    Fellows, I; Handcock, MS

    2012-01-01

    Random graphs, where the connections between nodes are considered random variables, have wide applicability in the social sciences. Exponential-family Random Graph Models (ERGM) have shown themselves to be a useful class of models for representing com- plex social phenomena. We generalize ERGM by also modeling nodal attributes as random variates, thus creating a random model of the full network, which we call Exponential-family Random Network Models (ERNM). We demonstrate how this framework a...

  19. Mondrian Forests: Efficient Online Random Forests

    OpenAIRE

    Lakshminarayanan, Balaji; Roy, Daniel M.; Teh, Yee Whye

    2014-01-01

    Ensembles of randomized decision trees, usually referred to as random forests, are widely used for classification and regression tasks in machine learning and statistics. Random forests achieve competitive predictive performance and are computationally efficient to train and test, making them excellent candidates for real-world prediction tasks. The most popular random forest variants (such as Breiman's random forest and extremely randomized trees) operate on batches of training data. Online ...

  20. Wave propagation and scattering in random media

    CERN Document Server

    Ishimaru, Akira

    1978-01-01

    Wave Propagation and Scattering in Random Media, Volume 2, presents the fundamental formulations of wave propagation and scattering in random media in a unified and systematic manner. The topics covered in this book may be grouped into three categories: waves in random scatterers, waves in random continua, and rough surface scattering. Random scatterers are random distributions of many particles. Examples are rain, fog, smog, hail, ocean particles, red blood cells, polymers, and other particles in a state of Brownian motion. Random continua are the media whose characteristics vary randomly an

  1. Randomization Resilient To Sensitive Reconstruction

    CERN Document Server

    Wang, Ke; Fu, Ada Waichee

    2012-01-01

    With the randomization approach, sensitive data items of records are randomized to protect privacy of individuals while allowing the distribution information to be reconstructed for data analysis. In this paper, we distinguish between reconstruction that has potential privacy risk, called micro reconstruction, and reconstruction that does not, called aggregate reconstruction. We show that the former could disclose sensitive information about a target individual, whereas the latter is more useful for data analysis than for privacy breaches. To limit the privacy risk of micro reconstruction, we propose a privacy definition, called (epsilon,delta)-reconstruction-privacy. Intuitively, this privacy notion requires that micro reconstruction has a large error with a large probability. The promise of this approach is that micro reconstruction is more sensitive to the number of independent trials in the randomization process than aggregate reconstruction is; therefore, reducing the number of independent trials helps a...

  2. RANDOM VARIABLE WITH FUZZY PROBABILITY

    Institute of Scientific and Technical Information of China (English)

    吕恩琳; 钟佑明

    2003-01-01

    Mathematic description about the second kind fuzzy random variable namely the random variable with crisp event-fuzzy probability was studied. Based on the interval probability and using the fuzzy resolution theorem, the feasible condition about a probability fuzzy number set was given, go a step further the definition arid characters of random variable with fuzzy probability ( RVFP ) and the fuzzy distribution function and fuzzy probability distribution sequence of the RVFP were put forward. The fuzzy probability resolution theorem with the closing operation of fuzzy probability was given and proved. The definition and characters of mathematical expectation and variance of the RVFP were studied also. All mathematic description about the RVFP has the closing operation for fuzzy probability, as a result, the foundation of perfecting fuzzy probability operation method is laid.

  3. Random Decrement Based FRF Estimation

    DEFF Research Database (Denmark)

    Brincker, Rune; Asmussen, J. C.

    The problem of estimating frequency response functions and extracting modal parameters is the topic of this paper. A new method based on the Random Decrement technique combined with Fourier transformation and the traditional pure Fourier transformation based approach is compared with regard to...... speed and quality. The basis of the new method is the Fourier transformation of the Random Decrement functions which can be used to estimate the frequency response functions. The investigations are based on load and response measurements of a laboratory model of a 3 span bridge. By applying both methods...... to these measurements the estimation time of the frequency response functions can be compared. The modal parameters estimated by the methods are compared. It is expected that the Random Decrement technique is faster than the traditional method based on pure Fourier Transformations. This is due to the...

  4. Random Decrement Based FRF Estimation

    DEFF Research Database (Denmark)

    Brincker, Rune; Asmussen, J. C.

    1997-01-01

    The problem of estimating frequency response functions and extracting modal parameters is the topic of this paper. A new method based on the Random Decrement technique combined with Fourier transformation and the traditional pure Fourier transformation based approach is compared with regard to...... speed and quality. The basis of the new method is the Fourier transformation of the Random Decrement functions which can be used to estimate the frequency response functions. The investigations are based on load and response measurements of a laboratory model of a 3 span bridge. By applying both methods...... to these measurements the estimation time of the frequency response functions can be compared. The modal parameters estimated by the methods are compared. It is expected that the Random Decrement technique is faster than the traditional method based on pure Fourier Transformations. This is due to the...

  5. How random are complex networks

    CERN Document Server

    Orsini, Chiara; Jamakovic, Almerima; Mahadevan, Priya; Colomer-de-Simón, Pol; Vahdat, Amin; Bassler, Kevin E; Toroczkai, Zoltán; Boguñá, Marián; Caldarelli, Guido; Fortunato, Santo; Krioukov, Dmitri

    2015-01-01

    Represented as graphs, real networks are intricate combinations of order and disorder. Fixing some of the structural properties of network models to their values observed in real networks, many other properties appear as statistical consequences of these fixed observables, plus randomness in other respects. Here we employ the $dk$-series, a complete set of basic characteristics of the network structure, to study the statistical dependencies between different network properties. We consider six real networks---the Internet, US airport network, human protein interactions, technosocial web of trust, English word network, and an fMRI map of the human brain---and find that many important local and global structural properties of these networks are closely reproduced by $dk$-random graphs whose degree distributions, degree correlations, and clustering are as in the corresponding real network. We discuss important conceptual, methodological, and practical implications of this evaluation of network randomness.

  6. A Randomized Experiment Comparing Random and Cutoff-Based Assignment

    Science.gov (United States)

    Shadish, William R.; Galindo, Rodolfo; Wong, Vivian C.; Steiner, Peter M.; Cook, Thomas D.

    2011-01-01

    In this article, we review past studies comparing randomized experiments to regression discontinuity designs, mostly finding similar results, but with significant exceptions. The latter might be due to potential confounds of study characteristics with assignment method or with failure to estimate the same parameter over methods. In this study, we…

  7. On the local time of random processes in random scenery

    CERN Document Server

    Castell, Fabienne; Pène, Françoise; Schapira, Bruno

    2012-01-01

    Random walks in random scenery are processes defined by $Z_n:=\\sum_{k=1}^n\\xi_{X_1+...+X_k}$, where basically $(X_k,k\\ge 1)$ and $(\\xi_y,y\\in\\mathbb Z)$ are two independent sequences of i.i.d. random variables. We assume here that $X_1$ is $\\ZZ$-valued, centered and with finite moments of all orders. We also assume that $\\xi_0$ is $\\ZZ$-valued, centered and square integrable. In this case H. Kesten and F. Spitzer proved that $(n^{-3/4}Z_{[nt]},t\\ge 0)$ converges in distribution as $n\\to \\infty$ toward some self-similar process $(\\Delta_t,t\\ge 0)$ called Brownian motion in random scenery. In a previous paper, we established that ${\\mathbb P}(Z_n=0)$ behaves asymptotically like a constant times $n^{-3/4}$, as $n\\to \\infty$. We extend here this local limit theorem: we give a precise asymptotic result for the probability for $Z$ to return to zero simultaneously at several times. As a byproduct of our computations, we show that $\\Delta$ admits a bi-continuous version of its local time process which is locally H\\"o...

  8. Ten weeks of physical-cognitive-mindfulness training reduces fear-avoidance beliefs about work-related activity: Randomized controlled trial.

    Science.gov (United States)

    Jay, Kenneth; Brandt, Mikkel; Jakobsen, Markus Due; Sundstrup, Emil; Berthelsen, Kasper Gymoese; Schraefel, Mc; Sjøgaard, Gisela; Andersen, Lars L

    2016-08-01

    People with chronic musculoskeletal pain often experience pain-related fear of movement and avoidance behavior. The Fear-Avoidance model proposes a possible mechanism at least partly explaining the development and maintenance of chronic pain. People who interpret pain during movement as being potentially harmful to the organism may initiate a vicious behavioral cycle by generating pain-related fear of movement accompanied by avoidance behavior and hyper-vigilance.This study investigates whether an individually adapted multifactorial approach comprised of biopsychosocial elements, with a focus on physical exercise, mindfulness, and education on pain and behavior, can decrease work-related fear-avoidance beliefs.As part of a large scale 10-week worksite randomized controlled intervention trial focusing on company initiatives to combat work-related musculoskeletal pain and stress, we evaluated fear-avoidance behavior in 112 female laboratory technicians with chronic neck, shoulder, upper back, lower back, elbow, and hand/wrist pain using the Fear-Avoidance Beliefs Questionnaire at baseline, before group allocation, and again at the post intervention follow-up 10 weeks later.A significant group by time interaction was observed (P pain. PMID:27559939

  9. Pants decompositions of random surfaces

    CERN Document Server

    Guth, Larry; Young, Robert

    2010-01-01

    Our goal is to show, in two different contexts, that "random" surfaces have large pants decompositions. First we show that there are hyperbolic surfaces of genus $g$ for which any pants decomposition requires curves of total length at least $g^{7/6 - \\epsilon}$. Moreover, we prove that this bound holds for most metrics in the moduli space of hyperbolic metrics equipped with the Weil-Petersson volume form. We then consider surfaces obtained by randomly gluing euclidean triangles (with unit side length) together and show that these surfaces have the same property.

  10. Random photonic crystal optical memory

    Science.gov (United States)

    Wirth Lima, A., Jr.; Sombra, A. S. B.

    2012-10-01

    Currently, optical cross-connects working on wavelength division multiplexing systems are based on optical fiber delay lines buffering. We designed and analyzed a novel photonic crystal optical memory, which replaces the fiber delay lines of the current optical cross-connect buffer. Optical buffering systems based on random photonic crystal optical memory have similar behavior to the electronic buffering systems based on electronic RAM memory. In this paper, we show that OXCs working with optical buffering based on random photonic crystal optical memories provides better performance than the current optical cross-connects.

  11. Truncations of random unitary matrices

    CERN Document Server

    Zyczkowski, K; Zyczkowski, Karol; Sommers, Hans-Juergen

    1999-01-01

    We analyze properties of non-hermitian matrices of size M constructed as square submatrices of unitary (orthogonal) random matrices of size N>M, distributed according to the Haar measure. In this way we define ensembles of random matrices and study the statistical properties of the spectrum located inside the unit circle. In the limit of large matrices, this ensemble is characterized by the ratio M/N. For the truncated CUE we derive analytically the joint density of eigenvalues from which easily all correlation functions are obtained. For N-M fixed and N--> infinity the universal resonance-width distribution with N-M open channels is recovered.

  12. Neutron transport in random media

    Energy Technology Data Exchange (ETDEWEB)

    Makai, M. [KFKI Atomic Energy Research Institute, Budapest (Hungary)

    1996-08-01

    The survey reviews the methods available in the literature which allow a discussion of corium recriticality after a severe accident and a characterization of the corium. It appears that to date no one has considered the eigenvalue problem, though for the source problem several approaches have been proposed. The mathematical formulation of a random medium may be approached in different ways. Based on the review of the literature, we can draw three basic conclusions. The problem of static, random perturbations has been solved. The static case is tractable by the Monte Carlo method. There is a specific time dependent case for which the average flux is given as a series expansion.

  13. Bose condensation in (random traps

    Directory of Open Access Journals (Sweden)

    V.A. Zagrebnov

    2009-01-01

    Full Text Available We study a non-interacting (perfect Bose-gas in random external potentials (traps. It is shown that a generalized Bose-Einstein condensation in the random eigenstates manifests if and only if the same occurs in the one-particle kinetic-energy eigenstates, which corresponds to the generalized condensation of the free Bose-gas. Moreover, we prove that the amounts of both condensate densities are equal. This statement is relevant for justification of the Bogoliubov approximation} in the theory of disordered boson systems.

  14. Consistency of Random Survival Forests.

    Science.gov (United States)

    Ishwaran, Hemant; Kogalur, Udaya B

    2010-07-01

    We prove uniform consistency of Random Survival Forests (RSF), a newly introduced forest ensemble learner for analysis of right-censored survival data. Consistency is proven under general splitting rules, bootstrapping, and random selection of variables-that is, under true implementation of the methodology. Under this setting we show that the forest ensemble survival function converges uniformly to the true population survival function. To prove this result we make one key assumption regarding the feature space: we assume that all variables are factors. Doing so ensures that the feature space has finite cardinality and enables us to exploit counting process theory and the uniform consistency of the Kaplan-Meier survival function.

  15. Automated Internet-based pain coping skills training to manage osteoarthritis pain: a randomized controlled trial.

    Science.gov (United States)

    Rini, Christine; Porter, Laura S; Somers, Tamara J; McKee, Daphne C; DeVellis, Robert F; Smith, Meredith; Winkel, Gary; Ahern, David K; Goldman, Roberta; Stiller, Jamie L; Mariani, Cara; Patterson, Carol; Jordan, Joanne M; Caldwell, David S; Keefe, Francis J

    2015-05-01

    Osteoarthritis (OA) places a significant burden on worldwide public health because of the large and growing number of people affected by OA and its associated pain and disability. Pain coping skills training (PCST) is an evidence-based intervention targeting OA pain and disability. To reduce barriers that currently limit access to PCST, we developed an 8-week, automated, Internet-based PCST program called PainCOACH and evaluated its potential efficacy and acceptability in a small-scale, 2-arm randomized controlled feasibility trial. Participants were 113 men and women with clinically confirmed hip or knee OA and associated pain. They were randomized to a group completing PainCOACH or an assessment-only control group. Osteoarthritis pain, pain-related interference with functioning, pain-related anxiety, self-efficacy for pain management, and positive and negative affect were measured before intervention, midway through the intervention, and after intervention. Findings indicated high acceptability and adherence: 91% of participants randomized to complete PainCOACH finished all 8 modules over 8 to 10 weeks. Linear mixed models showed that, after treatment, women who received the PainCOACH intervention reported significantly lower pain than that in women in the control group (Cohen d = 0.33). Intervention effects could not be tested in men because of their low pain and small sample size. Additionally, both men and women demonstrated increases in self-efficacy from baseline to after intervention compared with the control group (d = 0.43). Smaller effects were observed for pain-related anxiety (d = 0.20), pain-related interference with functioning (d = 0.13), negative affect (d = 0.10), and positive affect (d = 0.24). Findings underscore the value of continuing to develop an automated Internet-based approach to disseminate this empirically supported intervention.

  16. Random packing of digitized particles

    NARCIS (Netherlands)

    Korte, de A.C.J.; Brouwers, H.J.H.

    2012-01-01

    The random packing of regularly and irregularly shaped particles has been studied extensively. Within this paper, packing is studied from the perspective of digitized particles. These digitized particles are developed for and used in cellular automata systems, which are employed for the simple mathe

  17. Contributions to Random Energy Models

    CERN Document Server

    Jana, Nabin Kumar

    2007-01-01

    In this thesis, we consider several Random Energy Models. This includes Derrida's Random Energy Model (REM) and Generalized Random Energy Model (GREM) and a nonhierarchical version (BK-GREM) by Bolthausen and Kistler. The limiting free energy in all these models along with Word GREM, a model proposed by us, turn out to be a cute consequence of large deviation principle (LDP). This LDP argument allows us to consider non-Gaussian driving distributions as well as external field. We could also consider random trees as the underlying tree structure in GREM. In all these models, as expected, limiting free energy is not 'universal' unlike the SK model. However it is 'rate specific'. Consideration of non-Gaussian driving distribution as well as different driving distributions for the different levels of the underlying trees in GREM leads to interesting phenomena. For example in REM, if the Hamiltonian is Binomial with parameter $N$ and $p$ then the existence of phase transition depends on the parameter $p$. More prec...

  18. The DAHANCA 6 randomized trial

    DEFF Research Database (Denmark)

    Lyhne, Nina M; Primdahl, Hanne; Kristensen, Claus A;

    2015-01-01

    explored. PATIENTS AND METHODS: Six hundred and ninety-four patients with non-metastatic glottic SCC were randomized between six or five weekly fractions (fx/w) of radiotherapy to the same total dose. The median treatment time was 38 and 46days, respectively. The primary endpoint was loco-regional failure...

  19. Models of random graph hierarchies

    CERN Document Server

    Paluch, Robert; Holyst, Janusz

    2015-01-01

    We introduce two models of inclusion hierarchies: Random Graph Hierarchy (RGH) and Limited Random Graph Hierarchy (LRGH). In both models a set of nodes at a given hierarchy level is connected randomly, as in the Erd\\H{o}s-R\\'{e}nyi random graph, with a fixed average degree equal to a system parameter $c$. Clusters of the resulting network are treated as nodes at the next hierarchy level and they are connected again at this level and so on, until the process cannot continue. In the RGH model we use all clusters, including those of size $1$, when building the next hierarchy level, while in the LRGH model clusters of size $1$ stop participating in further steps. We find that in both models the number of nodes at a given hierarchy level $h$ decreases approximately exponentially with $h$. The height of the hierarchy $H$, i.e. the number of all hierarchy levels, increases logarithmically with the system size $N$, i.e. with the number of nodes at the first level. The height $H$ decreases monotonically with the conne...

  20. Registration of randomized clinical trials

    DEFF Research Database (Denmark)

    Østervig, R M; Sonne, A; Rasmussen, L S

    2015-01-01

    starting enrolment before 2010 to 63.2% after 2010 (24/38, P clinical trials were registered at clinicaltrials.gov. CONCLUSION: Many published randomized controlled trials from Acta Anaesthesiologica Scandinavica were not adequately registered but the requirement of trial registration has...

  1. Randomized clinical trials in HEPATOLOGY

    DEFF Research Database (Denmark)

    Kjaergard, L L; Nikolova, D; Gluud, C

    1999-01-01

    Evidence shows that the quality of randomized clinical trials (RCTs) affects estimates of intervention efficacy, which is significantly exaggerated in low-quality trials. The present study examines the quality of all 235 RCTs published in HEPATOLOGY from the initiation in 1981 through August 1998...

  2. Asymptotics of weighted random sums

    DEFF Research Database (Denmark)

    Corcuera, José Manuel; Nualart, David; Podolskij, Mark

    2014-01-01

    In this paper we study the asymptotic behaviour of weighted random sums when the sum process converges stably in law to a Brownian motion and the weight process has continuous trajectories, more regular than that of a Brownian motion. We show that these sums converge in law to the integral of the...

  3. Beyond the random phase approximation

    DEFF Research Database (Denmark)

    Olsen, Thomas; Thygesen, Kristian S.

    2013-01-01

    We assess the performance of a recently proposed renormalized adiabatic local density approximation (rALDA) for ab initio calculations of electronic correlation energies in solids and molecules. The method is an extension of the random phase approximation (RPA) derived from time-dependent density...

  4. Universality in random quantum networks

    Science.gov (United States)

    Novotný, Jaroslav; Alber, Gernot; Jex, Igor

    2015-12-01

    Networks constitute efficient tools for assessing universal features of complex systems. In physical contexts, classical as well as quantum networks are used to describe a wide range of phenomena, such as phase transitions, intricate aspects of many-body quantum systems, or even characteristic features of a future quantum internet. Random quantum networks and their associated directed graphs are employed for capturing statistically dominant features of complex quantum systems. Here, we develop an efficient iterative method capable of evaluating the probability of a graph being strongly connected. It is proven that random directed graphs with constant edge-establishing probability are typically strongly connected, i.e., any ordered pair of vertices is connected by a directed path. This typical topological property of directed random graphs is exploited to demonstrate universal features of the asymptotic evolution of large random qubit networks. These results are independent of our knowledge of the details of the network topology. These findings suggest that other highly complex networks, such as a future quantum internet, may also exhibit similar universal properties.

  5. Fatigue Reliability under Random Loads

    DEFF Research Database (Denmark)

    Talreja, R.

    1979-01-01

    , with the application of random loads, the initial homogeneous distribution of strength changes to a two-component distribution, reflecting the two-stage fatigue damage. In the crack initiation stage, the strength increases initially and then decreases, while an abrupt decrease of strength is seen in the crack...... propagation stage. The consequences of this behaviour on the fatigue reliability are discussed....

  6. Effect of an office worksite-based yoga program on heart rate variability: A randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Chang Dennis

    2011-07-01

    Full Text Available Abstract Background Chronic work-related stress is a significant and independent risk factor for cardiovascular and metabolic diseases and associated mortality, particularly when compounded by a sedentary work environment. Heart rate variability (HRV provides an estimate of parasympathetic and sympathetic autonomic control, and can serve as a marker of physiological stress. Hatha yoga is a physically demanding practice that can help to reduce stress; however, time constraints incurred by work and family life may limit participation. The purpose of the present study is to determine if a 10-week, worksite-based yoga program delivered during lunch hour can improve resting HRV and related physical and psychological parameters in sedentary office workers. Methods and design This is a parallel-arm RCT that will compare the outcomes of participants assigned to the experimental treatment group (yoga to those assigned to a no-treatment control group. Participants randomized to the experimental condition will engage in a 10-week yoga program delivered at their place of work. The yoga sessions will be group-based, prescribed three times per week during lunch hour, and will be led by an experienced yoga instructor. The program will involve teaching beginner students safely and progressively over 10 weeks a yoga sequence that incorporates asanas (poses and postures, vinyasa (exercises, pranayama (breathing control and meditation. The primary outcome of this study is the high frequency (HF spectral power component of HRV (measured in absolute units; i.e. ms2, a measure of parasympathetic autonomic control. Secondary outcomes include additional frequency and time domains of HRV, and measures of physical functioning and psychological health status. Measures will be collected prior to and following the intervention period, and at 6 months follow-up to determine the effect of intervention withdrawal. Discussion This study will determine the effect of worksite

  7. A Mixed Effects Randomized Item Response Model

    Science.gov (United States)

    Fox, J.-P.; Wyrick, Cheryl

    2008-01-01

    The randomized response technique ensures that individual item responses, denoted as true item responses, are randomized before observing them and so-called randomized item responses are observed. A relationship is specified between randomized item response data and true item response data. True item response data are modeled with a (non)linear…

  8. Random fixed point theorems on product spaces

    OpenAIRE

    Ismat Beg; Naseer Shahzad

    1993-01-01

    The existence of random fixed point of a locally contractive random operator in first variable on product spaces is proved. The concept “continuous random height-selection” is discussed. Some random fixed point theorems for nonexpansive self and nonself maps are also obtained in product spaces.

  9. Random trinomial tree models and vanilla options

    Science.gov (United States)

    Ganikhodjaev, Nasir; Bayram, Kamola

    2013-09-01

    In this paper we introduce and study random trinomial model. The usual trinomial model is prescribed by triple of numbers (u, d, m). We call the triple (u, d, m) an environment of the trinomial model. A triple (Un, Dn, Mn), where {Un}, {Dn} and {Mn} are the sequences of independent, identically distributed random variables with 0 < Dn < 1 < Un and Mn = 1 for all n, is called a random environment and trinomial tree model with random environment is called random trinomial model. The random trinomial model is considered to produce more accurate results than the random binomial model or usual trinomial model.

  10. Randomizing task placement does not randomize traffic (enough)

    OpenAIRE

    Jokanovic, Ana; Prisacari, Bogdan; Rodriguez, German; Minkenberg, Cyriel

    2013-01-01

    Dragonflies are one of the most promising topologies for the Exascale effort for their scalability and cost. Dragonflies achieve very high throughput under uniform traffic, but have a pathological behavior under other regular traffic patterns, some of them very common in HPC applications. A recent study showed that randomization of task placement can make pathological, regular (multi-dimensional stencil) traffic patterns behave similar to uniform traffic. In this work we provide a theoret...

  11. Random density matrices versus random evolution of open system

    Science.gov (United States)

    Pineda, Carlos; Seligman, Thomas H.

    2015-10-01

    We present and compare two families of ensembles of random density matrices. The first, static ensemble, is obtained foliating an unbiased ensemble of density matrices. As criterion we use fixed purity as the simplest example of a useful convex function. The second, dynamic ensemble, is inspired in random matrix models for decoherence where one evolves a separable pure state with a random Hamiltonian until a given value of purity in the central system is achieved. Several families of Hamiltonians, adequate for different physical situations, are studied. We focus on a two qubit central system, and obtain exact expressions for the static case. The ensemble displays a peak around Werner-like states, modulated by nodes on the degeneracies of the density matrices. For moderate and strong interactions good agreement between the static and the dynamic ensembles is found. Even in a model where one qubit does not interact with the environment excellent agreement is found, but only if there is maximal entanglement with the interacting one. The discussion is started recalling similar considerations for scattering theory. At the end, we comment on the reach of the results for other convex functions of the density matrix, and exemplify the situation with the von Neumann entropy.

  12. Design and rationale of a randomized controlled trial of melatonin supplementation in men and women with the metabolic syndrome

    Directory of Open Access Journals (Sweden)

    Terry PD

    2013-03-01

    Full Text Available Paul D Terry,1 Abhinav Goyal,2,3 Lawrence S Phillips,3 Hillary M Superak,4 Michael H Kutner4 1Departments of Public Health and Surgery, University of Tennessee, Knoxville, TN, 2Department of Epidemiology, Emory Rollins School of Public Health, 3Department of Medicine, Emory School of Medicine, 4Department of Biostatistics and Bioinformatics, Emory Rollins School of Public Health, Atlanta, GA, USA Background: The metabolic syndrome is a constellation of interrelated metabolic risk factors that appear to increase the risk of atherosclerotic cardiovascular disease, type 2 diabetes mellitus, and possibly some cancers. Animal studies and observational clinical data in humans suggest that supplemental melatonin may ameliorate a number of components of the metabolic syndrome, including elevated glucose, elevated blood pressure, dyslipidemia, and obesity. The primary objective of this clinical trial was to determine the feasibility, efficacy, and safety of melatonin supplementation in men and women with the metabolic syndrome. Methods: Thirty-nine men and women of mixed race/ethnicity were enrolled into a randomized, double-blind, placebo-controlled clinical trial with two arms: placebo for 10 weeks followed by melatonin for 10 weeks, or vice versa, with an interval 6-week washout period, in a crossover trial design. Outcome measures include metabolic syndrome components (blood pressure, glucose, triglycerides, high-density lipoprotein cholesterol, waist circumference, oxidative stress, and inflammation biomarkers. These biomarkers, along with sleep duration and quality and pretreatment endogenous melatonin levels, were measured to explore possible underlying biologic mechanisms. Discussion: This trial will provide knowledge of the effects of melatonin in metabolic syndrome subjects, and lay the groundwork for future clinical trials of melatonin in metabolic syndrome subjects. Keywords: melatonin, metabolic syndrome, diabetes, blood pressure, sleep

  13. Randomized Experiments as the Bronze Standard

    OpenAIRE

    Berk, Richard

    2011-01-01

    In this paper, the strengths and weakness of randomized field ex- periments are discussed. Although it seems to be common knowledge that random assignment balances experimental and control groups on all confounders, other features of randomized field experiments are somewhat less appreciated. These include the role of random assign- ment in statistical inference and representations of the mechanisms by which the treatment has its impact. Randomized experiments also have important limit...

  14. Random tensor theory: extending random matrix theory to random product states

    CERN Document Server

    Ambainis, Andris; Hastings, Matthew B

    2009-01-01

    We consider a problem in random matrix theory that is inspired by quantum information theory: determining the largest eigenvalue of a sum of p random product states in (C^d)^{otimes k}, where k and p/d^k are fixed while d grows. When k=1, the Marcenko-Pastur law determines (up to small corrections) not only the largest eigenvalue ((1+sqrt{p/d^k})^2) but the smallest eigenvalue (min(0,1-sqrt{p/d^k})^2) and the spectral density in between. We use the method of moments to show that for k>1 the largest eigenvalue is still approximately (1+sqrt{p/d^k})^2 and the spectral density approaches that of the Marcenko-Pastur law, generalizing the random matrix theory result to the random tensor case. Our bound on the largest eigenvalue has implications for a recently proposed quantum data hiding scheme due to Leung and Winter. Since the matrices we consider have neither independent entries nor unitary invariance, we need to develop new techniques for their analysis. The main contribution of this paper is to give three dif...

  15. Random walk near the surface

    Science.gov (United States)

    Korneta, W.; Pytel, Z.

    1988-07-01

    The random walk of a particle on a three-dimensional semi-infinite lattice is considered. In order to study the effect of the surface on the random walk, it is assumed that the velocity of the particle depends on the distance to the surface. Moreover it is assumed that at any point the particle may be absorbed with a certain probability. The probability of the return of the particle to the starting point and the average time of eventual return are calculated. The dependence of these quantities on the distance to the surface, the probability of absorption and the properties of the surface is discussed. The method of generating functions is used.

  16. Orientability thresholds for random hypergraphs

    CERN Document Server

    Gao, Pu

    2010-01-01

    Let $h>w>0$ be two fixed integers. Let $\\orH$ be a random hypergraph whose hyperedges are all of cardinality $h$. To {\\em $w$-orient} a hyperedge, we assign exactly $w$ of its vertices positive signs with respect to the hyperedge, and the rest negative. A $(w,k)$-orientation of $\\orH$ consists of a $w$-orientation of all hyperedges of $\\orH$, such that each vertex receives at most $k$ positive signs from its incident hyperedges. When $k$ is large enough, we determine the threshold of the existence of a $(w,k)$-orientation of a random hypergraph. The $(w,k)$-orientation of hypergraphs is strongly related to a general version of the off-line load balancing problem. The graph case, when $h=2$ and $w=1$, was solved recently by Cain, Sanders and Wormald and independently by Fernholz and Ramachandran, which settled a conjecture of Karp and Saks.

  17. Dynamics of random spin systems

    International Nuclear Information System (INIS)

    We present inelastic neutron scattering experiments on three prototypical random magnets. For the dilute, insulating antiferromagnet Rb2Co/sub c/Mg/sub 1-c/F4, the randomness has purely geometrical consequences, and the anomalous dynamical behavior which we observe for c close to the magnetic percolation threshold is due to the fractal nature of percolating networks. Comparison of inelastic and quasielastic scattering data demonstrate the dynamical nature of the spin glass transition in amorphous, metallic MnSi. Finally, we show the coexistence of spin waves and static spin fluctuations near the crossover from ferromagnetic to spin glass behaviors in amorphous (Fe/sub x/Mn/sub 1-x/)75P16B6Al3

  18. Logical independence and quantum randomness

    Energy Technology Data Exchange (ETDEWEB)

    Paterek, T; Kofler, J; Aspelmeyer, M; Zeilinger, A; Brukner, C [Institute for Quantum Optics and Quantum Information, Austrian Academy of Sciences, Boltzmanngasse 3, A-1090 Vienna (Austria); Prevedel, R; Klimek, P [Faculty of Physics, University of Vienna, Boltzmanngasse 5, A-1090 Vienna (Austria)], E-mail: tomasz.paterek@univie.ac.at

    2010-01-15

    We propose a link between logical independence and quantum physics. We demonstrate that quantum systems in the eigenstates of Pauli group operators are capable of encoding mathematical axioms and show that Pauli group quantum measurements are capable of revealing whether or not a given proposition is logically dependent on the axiomatic system. Whenever a mathematical proposition is logically independent of the axioms encoded in the measured state, the measurement associated with the proposition gives random outcomes. This allows for an experimental test of logical independence. Conversely, it also allows for an explanation of the probabilities of random outcomes observed in Pauli group measurements from logical independence without invoking quantum theory. The axiomatic systems we study can be completed and are therefore not subject to Goedel's incompleteness theorem.

  19. Knot probabilities in random diagrams

    Science.gov (United States)

    Cantarella, Jason; Chapman, Harrison; Mastin, Matt

    2016-10-01

    We consider a natural model of random knotting—choose a knot diagram at random from the finite set of diagrams with n crossings. We tabulate diagrams with 10 and fewer crossings and classify the diagrams by knot type, allowing us to compute exact probabilities for knots in this model. As expected, most diagrams with 10 and fewer crossings are unknots (about 78% of the roughly 1.6 billion 10 crossing diagrams). For these crossing numbers, the unknot fraction is mostly explained by the prevalence of ‘tree-like’ diagrams which are unknots for any assignment of over/under information at crossings. The data shows a roughly linear relationship between the log of knot type probability and the log of the frequency rank of the knot type, analogous to Zipf’s law for word frequency. The complete tabulation and all knot frequencies are included as supplementary data.

  20. Random matrices: Universality of eigenvectors

    CERN Document Server

    Tao, Terence

    2011-01-01

    The four moment theorem asserts, roughly speaking, that the joint distribution of a small number of eigenvalues of a Wigner random matrix (when measured at the scale of the mean eigenvalue spacing) depends only on the first four moments of the entries of the matrix. In this paper, we extend the four moment theorem to also cover the coefficients of the \\emph{eigenvectors} of a Wigner random matrix. A similar result (with different hypotheses) has been proved recently by Knowles and Yin, using a different method. As an application, we prove some central limit theorems for these eigenvectors. In another application, we prove a universality result for the resolvent, up to the real axis. This implies universality of the inverse matrix.

  1. Pancyclic subgraphs of random graphs

    CERN Document Server

    Lee, Choongbum

    2010-01-01

    An $n$-vertex graph is called pancyclic if it contains a cycle of length $t$ for all $3 \\leq t \\leq n$. In this paper, we study pancyclicity of random graphs in the context of resilience, and prove that if $p \\gg n^{-1/2}$, then the random graph $G(n,p)$ a.a.s. satisfies the following property: Every Hamiltonian subgraph of $G(n,p)$ with more than $(\\frac{1}{2} + o(1)){n \\choose 2}p$ edges is pancyclic. This result is best possible in two ways. First, the range of $p$ is asymptotically tight; second, the proportion $\\frac{1}{2}$ of edges cannot be reduced. Our theorem extends a classical theorem of Bondy, and is closely related to a recent work of Krivelevich, Lee, and Sudakov. The proof uses a recent result of Schacht (also independently obtained by Conlon and Gowers).

  2. The weighted random graph model

    Science.gov (United States)

    Garlaschelli, Diego

    2009-07-01

    We introduce the weighted random graph (WRG) model, which represents the weighted counterpart of the Erdos-Renyi random graph and provides fundamental insights into more complicated weighted networks. We find analytically that the WRG is characterized by a geometric weight distribution, a binomial degree distribution and a negative binomial strength distribution. We also characterize exactly the percolation phase transitions associated with edge removal and with the appearance of weighted subgraphs of any order and intensity. We find that even this completely null model displays a percolation behaviour similar to what is observed in real weighted networks, implying that edge removal cannot be used to detect community structure empirically. By contrast, the analysis of clustering successfully reveals different patterns between the WRG and real networks.

  3. Monochromatic Progressions in Random Colorings

    OpenAIRE

    Vijay, Sujith

    2011-01-01

    Let N^{+}(k)= 2^{k/2} k^{3/2} f(k) and N^{-}(k)= 2^{k/2} k^{1/2} g(k) where 1=o(f(k)) and g(k)=o(1). We show that the probability of a random 2-coloring of {1,2,...,N^{+}(k)} containing a monochromatic k-term arithmetic progression approaches 1, and the probability of a random 2-coloring of {1,2,...,N^{-}(k)} containing a monochromatic k-term arithmetic progression approaches 0, for large k. This improves an upper bound due to Brown, who had established an analogous result for N^{+}(k)= 2^k l...

  4. Localization of reinforced random walks

    CERN Document Server

    Tarrès, Pierre

    2011-01-01

    We describe and analyze how reinforced random walks can eventually localize, i.e. only visit finitely many sites. After introducing vertex and edge self-interacting walks on a discrete graph in a general setting, and stating the main results and conjectures so far on the topic, we present martingale techniques that provide an alternative proof of the a.s. localization of vertex-reinforced random walks (VRRWs) on the integers on finitely many sites and, with positive probability, on five consecutive sites, initially proved by Pemantle and Volkov (1999). Next we introduce the continuous time-lines representation (sometimes called Rubin construction) and its martingale counterpart, and explain how it has been used to prove localization of some reinforced walks on one attracting edge. Then we show how a modified version of this construction enables one to propose a new short proof of the a.s. localization of VRRWs on five sites on Z.

  5. Dynamical invariance for random matrices

    CERN Document Server

    Unterberger, Jeremie

    2016-01-01

    We consider a general Langevin dynamics for the one-dimensional N-particle Coulomb gas with confining potential $V$ at temperature $\\beta$. These dynamics describe for $\\beta=2$ the time evolution of the eigenvalues of $N\\times N$ random Hermitian matrices. The equilibrium partition function -- equal to the normalization constant of the Laughlin wave function in fractional quantum Hall effect -- is known to satisfy an infinite number of constraints called Virasoro or loop constraints. We introduce here a dynamical generating function on the space of random trajectories which satisfies a large class of constraints of geometric origin. We focus in this article on a subclass induced by the invariance under the Schr\\"odinger-Virasoro algebra.

  6. Coherence protection by random coding

    Energy Technology Data Exchange (ETDEWEB)

    Brion, E [Laboratoire Aime Cotton, CNRS II, Batiment 505, 91405 Orsay Cedex (France); Akulin, V M [Laboratoire Aime Cotton, CNRS II, Batiment 505, 91405 Orsay Cedex (France); Dumer, I [College of Engineering, University of California, Riverside, CA 92521 (United States); Harel, G [Spinoza Institute, Utrecht University, Leuvenlaan 4, 3508 TD Utrecht (Netherlands); Kurizki, G [Department of Chemical Physics, Weizmann Institute of Science, Rehovot 76100 (Israel)

    2005-10-01

    We show that the multidimensional Zeno effect combined with non-holonomic control allows one to efficiently protect quantum systems from decoherence by a method similar to classical random coding. The method is applicable to arbitrary error-inducing Hamiltonians and general quantum systems. The quantum encoding approaches the Hamming upper bound for large dimension increases. Applicability of the method is demonstrated with a seven-qubit toy computer.

  7. Squares of Random Linear Codes

    DEFF Research Database (Denmark)

    Cascudo Pueyo, Ignacio; Cramer, Ronald; Mirandola, Diego;

    2015-01-01

    a positive answer, for codes of dimension $k$ and length roughly $\\frac{1}{2}k^2$ or smaller. Moreover, the convergence speed is exponential if the difference $k(k+1)/2-n$ is at least linear in $k$. The proof uses random coding and combinatorial arguments, together with algebraic tools involving the precise...... computation of the number of quadratic forms of a given rank, and the number of their zeros....

  8. Random Forests for Poverty Classification

    OpenAIRE

    Ruben Thoplan

    2014-01-01

    This paper applies a relatively novel method in data mining to address the issue of poverty classification in Mauritius. The random forests algorithm is applied to the census data in view of improving classification accuracy for poverty status. The analysis shows that the numbers of hours worked, age, education and sex are the most important variables in the classification of the poverty status of an individual. In addition, a clear poverty-gender gap is identified as women have higher chance...

  9. Maximum matching on random graphs

    OpenAIRE

    Zhou, Haijun; Ou-Yang, Zhong-Can

    2003-01-01

    The maximum matching problem on random graphs is studied analytically by the cavity method of statistical physics. When the average vertex degree \\mth{c} is larger than \\mth{2.7183}, groups of max-matching patterns which differ greatly from each other {\\em gradually} emerge. An analytical expression for the max-matching size is also obtained, which agrees well with computer simulations. Discussion is made on this {\\em continuous} glassy phase transition and the absence of such a glassy phase ...

  10. Analyzing Walksat on random formulas

    CERN Document Server

    Coja-Oghlan, Amin

    2011-01-01

    Let F be a uniformly distributed random k-SAT formula with n variables and m clauses. We prove that the Walksat algorithm from Papadimitriou (FOCS 1991)/Schoning (FOCS 1999) finds a satisfying assignment of F in polynomial time w.h.p. if m/n0. This is an improvement by a factor of $\\Theta(k)$ over the best previous analysis of Walksat from Coja-Oghlan, Feige, Frieze, Krivelevich, Vilenchik (SODA 2009).

  11. Optimal Insurance Under Random Auditing

    OpenAIRE

    Marie-Cécile Fagart; Pierre Picard

    1998-01-01

    We provide a characterization of an optimal insurance contract (coverage schedule and audit policy) when the monitoring procedure is random. When the policyholder exhibits constant absolute risk aversion, the optimal contract involves a positive indemnity payment with a deductible when the magnitude of damages exceeds a threshold. In such a case, marginal damages are fully covered if the claim is verified. Otherwise, there is an additional deductible that disappears when the damages become in...

  12. Topological insulators in random potentials

    Science.gov (United States)

    Pieper, Andreas; Fehske, Holger

    2016-01-01

    We investigate the effects of magnetic and nonmagnetic impurities on the two-dimensional surface states of three-dimensional topological insulators (TIs). Modeling weak and strong TIs using a generic four-band Hamiltonian, which allows for a breaking of inversion and time-reversal symmetries and takes into account random local potentials as well as the Zeeman and orbital effects of external magnetic fields, we compute the local density of states, the single-particle spectral function, and the conductance for a (contacted) slab geometry by numerically exact techniques based on kernel polynomial expansion and Green's function approaches. We show that bulk disorder refills the surface-state Dirac gap induced by a homogeneous magnetic field with states, whereas orbital (Peierls-phase) disorder preserves the gap feature. The former effect is more pronounced in weak TIs than in strong TIs. At moderate randomness, disorder-induced conducting channels appear in the surface layer, promoting diffusive metallicity. Random Zeeman fields rapidly destroy any conducting surface states. Imprinting quantum dots on a TI's surface, we demonstrate that carrier transport can be easily tuned by varying the gate voltage, even to the point where quasibound dot states may appear.

  13. On Why and What of Randomness

    CERN Document Server

    Chakraborty, Soubhik

    2009-01-01

    This paper has several objectives. First, it separates randomness from lawlessness and shows why even genuine randomness does not imply lawlessness. Second, it separates the question -why should I call a phenomenon random? (and answers it in part one) from the patent question -What is a random sequence? -for which the answer lies in Kolmogorov complexity (which is explained in part two). While answering the first question the note argues why there should be four motivating factors for calling a phenomenon random: ontic, epistemic, pseudo and telescopic, the first two depicting genuine randomness and the last two false. Third, ontic and epistemic randomness have been distinguished from ontic and epistemic probability. Fourth, it encourages students to be applied statisticians and advises against becoming armchair theorists but this is interestingly achieved by a straight application of telescopic randomness. Overall, it tells (the teacher) not to jump to probability without explaining randomness properly first...

  14. True random numbers from amplified quantum vacuum

    CERN Document Server

    Jofre, M; Steinlechner, F; Anzolin, G; Torres, J P; Mitchell, M W; Pruneri, V; 10.1364/OE.19.020665

    2011-01-01

    Random numbers are essential for applications ranging from secure communications to numerical simulation and quantitative finance. Algorithms can rapidly produce pseudo-random outcomes, series of numbers that mimic most properties of true random numbers while quantum random number generators (QRNGs) exploit intrinsic quantum randomness to produce true random numbers. Single-photon QRNGs are conceptually simple but produce few random bits per detection. In contrast, vacuum fluctuations are a vast resource for QRNGs: they are broad-band and thus can encode many random bits per second. Direct recording of vacuum fluctuations is possible, but requires shot-noise-limited detectors, at the cost of bandwidth. We demonstrate efficient conversion of vacuum fluctuations to true random bits using optical amplification of vacuum and interferometry. Using commercially-available optical components we demonstrate a QRNG at a bit rate of 1.11 Gbps. The proposed scheme has the potential to be extended to 10 Gbps and even up t...

  15. Permutation Entropy for Random Binary Sequences

    Directory of Open Access Journals (Sweden)

    Lingfeng Liu

    2015-12-01

    Full Text Available In this paper, we generalize the permutation entropy (PE measure to binary sequences, which is based on Shannon’s entropy, and theoretically analyze this measure for random binary sequences. We deduce the theoretical value of PE for random binary sequences, which can be used to measure the randomness of binary sequences. We also reveal the relationship between this PE measure with other randomness measures, such as Shannon’s entropy and Lempel–Ziv complexity. The results show that PE is consistent with these two measures. Furthermore, we use PE as one of the randomness measures to evaluate the randomness of chaotic binary sequences.

  16. Human action analysis with randomized trees

    CERN Document Server

    Yu, Gang; Liu, Zicheng

    2014-01-01

    This book will provide a comprehensive overview on human action analysis with randomized trees. It will cover both the supervised random trees and the unsupervised random trees. When there are sufficient amount of labeled data available, supervised random trees provides a fast method for space-time interest point matching. When labeled data is minimal as in the case of example-based action search, unsupervised random trees is used to leverage the unlabelled data. We describe how the randomized trees can be used for action classification, action detection, action search, and action prediction.

  17. Random Dieudonne modules, random p-divisible groups, and random curves over finite fields

    CERN Document Server

    Cais, Bryden; Zureick-Brown, David

    2012-01-01

    We describe a probability distribution on isomorphism classes of principally quasi-polarized p-divisible groups over a finite field k of characteristic p which can reasonably be thought of as "uniform distribution," and we compute the distribution of various statistics (p-corank, a-number, etc.) of p-divisible groups drawn from this distribution. It is then natural to ask to what extent the p-divisible groups attached to a randomly chosen hyperelliptic curve (resp. curve, resp. abelian variety) over k are uniformly distributed in this sense. For instance, one can ask whether the proportion of genus-g curves over F_p whose Jacobian is ordinary approaches the limit that such a heuristic would predict. This heuristic is analogous to conjectures of Cohen-Lenstra type for fields k of characteristic other than p, in which case the random p-divisible group is defined by a random matrix recording the action of Frobenius. Extensive numerical investigation reveals some cases of agreement with the heuristic and some int...

  18. Random fixed points of non-self maps and random approximations

    Directory of Open Access Journals (Sweden)

    Ismat Beg

    1997-01-01

    Full Text Available In this paper we prove random fixed point theorems in reflexive Banach spaces for nonexpansive random operators satisfying inward or Leray-Schauder condition and establish a random approximation theorem.

  19. Large deviations for random walk in a random environment

    CERN Document Server

    Yilmaz, Atilla

    2008-01-01

    In this work, we study the large deviation properties of random walk in a random environment on $\\mathbb{Z}^d$ with $d\\geq1$. We start with the quenched case, take the point of view of the particle, and prove the large deviation principle (LDP) for the pair empirical measure of the environment Markov chain. By an appropriate contraction, we deduce the quenched LDP for the mean velocity of the particle and obtain a variational formula for the corresponding rate function $I_q$. We propose an Ansatz for the minimizer of this formula. This Ansatz is easily verified when $d=1$. In his 2003 paper, Varadhan proves the averaged LDP for the mean velocity and gives a variational formula for the corresponding rate function $I_a$. Under the non-nestling assumption (resp. Kalikow's condition), we show that $I_a$ is strictly convex and analytic on a non-empty open set $\\mathcal{A}$, and that the true velocity $\\xi_o$ is an element (resp. in the closure) of $\\mathcal{A}$. We then identify the minimizer of Varadhan's variati...

  20. Galantamine efficacy and tolerability as an augmentative therapy in autistic children: A randomized, double-blind, placebo-controlled trial.

    Science.gov (United States)

    Ghaleiha, Ali; Ghyasvand, Mohammad; Mohammadi, Mohammad-Reza; Farokhnia, Mehdi; Yadegari, Noorollah; Tabrizi, Mina; Hajiaghaee, Reza; Yekehtaz, Habibeh; Akhondzadeh, Shahin

    2014-07-01

    The role of cholinergic abnormalities in autism was recently evidenced and there is a growing interest in cholinergic modulation, emerging for targeting autistic symptoms. Galantamine is an acetylcholinesterase inhibitor and an allosteric potentiator of nicotinic receptors. This study aimed to evaluate the possible effects of galantamine as an augmentative therapy to risperidone, in autistic children. In this randomized, double-blind, placebo-controlled, parallel-group study, 40 outpatients aged 4-12 years whom had a diagnosis of autism (DSM IV-TR) and a score of 12 or higher on the Aberrant Behavior Checklist-Community (ABC-C) Irritability subscale were equally randomized to receive either galantamine (up to 24 mg/day) or placebo, in addition to risperidone (up to 2 mg/day), for 10 weeks. We rated participants by ABC-C and a side effects checklist, at baseline and at weeks 5 and 10. By the study endpoint, the galantamine-treated patients showed significantly greater improvement in the Irritability (P = 0.017) and Lethargy/Social Withdrawal (P = 0.005) subscales than the placebo group. The difference between the two groups in the frequency of side effects was not significant. In conclusion, galantamine augmentation was shown to be a relatively effective and safe augmentative strategy for alleviating some of the autism-related symptoms.

  1. Randomized clinical trial of multimodal physiotherapy treatment compared to overnight lidocaine ointment in women with provoked vestibulodynia: Design and methods.

    Science.gov (United States)

    Morin, Mélanie; Dumoulin, Chantale; Bergeron, Sophie; Mayrand, Marie-Hélène; Khalifé, Samir; Waddell, Guy; Dubois, Marie-France

    2016-01-01

    Provoked vestibulodynia (PVD) is a highly prevalent and debilitating condition yet its management relies mainly on non-empirically validated interventions. Among the many causes of PVD, there is growing evidence that pelvic floor muscle (PFM) dysfunctions play an important role in its pathophysiology. Multimodal physiotherapy, which addresses these dysfunctions, is judged by experts to be highly effective and is recommended as a first-line treatment. However, the effectiveness of this promising intervention has been evaluated through only two small uncontrolled trials. The proposed bi-center, single-blind, parallel group, randomized controlled trial (RCT) aims to evaluate the efficacy of multimodal physiotherapy and compare it to a frequently used first-line treatment, topical overnight application of lidocaine, in women with PVD. A total of 212 women diagnosed with PVD according to a standardized protocol were eligible for the study and were randomly assigned to either multimodal physiotherapy or lidocaine treatment for 10weeks. The primary outcome measure is pain during intercourse (assessed with a numerical rating scale). Secondary measures include sexual function, pain quality, psychological factors (including pain catastrophizing, anxiety, depression and fear of pain), PFM morphology and function, and patients' global impression of change. Assessments are made at baseline, post-treatment and at the 6-month follow-up. This manuscript presents and discusses the rationale, design and methodology of the first RCT investigating physiotherapy in comparison to a commonly prescribed first-line treatment, overnight topical lidocaine, for women with PVD.

  2. Large gaps between random eigenvalues

    OpenAIRE

    Valkó, Benedek; Virág, Bálint

    2010-01-01

    We show that in the point process limit of the bulk eigenvalues of $\\beta$-ensembles of random matrices, the probability of having no eigenvalue in a fixed interval of size $\\lambda$ is given by \\[\\bigl(\\ kappa_{\\beta}+o(1)\\bigr)\\lambda^{\\gamma_{\\beta}}\\exp\\biggl(-{\\bet a}{64}\\lambda^2+\\biggl({\\beta}{8}-{1}{4}\\biggr)\\lambda\\biggr)\\] as $\\lambda\\to\\infty$, where \\[\\gamma_{\\beta}={1}{4}\\biggl({\\beta}{2}+{2}{\\beta}-3\\biggr)\\] and $\\kappa_{\\beta}$ is an undetermined positive constant. This is a s...

  3. Gaps in discrete random samples

    OpenAIRE

    Grübel, Rudolf; Hitczenko, Paweł

    2009-01-01

    Let (Xi)i∈ℕ be a sequence of independent and identically distributed random variables with values in the set ℕ0 of nonnegative integers. Motivated by applications in enumerative combinatorics and analysis of algorithms we investigate the number of gaps and the length of the longest gap in the set {X1,...,Xn} of the first n values. We obtain necessary and sufficient conditions in terms of the tail sequence (qk)k∈ℕ0, qk=P(X1≥ k), for the gaps to vanish ...

  4. Random Matrix Theory and Econophysics

    Science.gov (United States)

    Rosenow, Bernd

    2000-03-01

    Random Matrix Theory (RMT) [1] is used in many branches of physics as a ``zero information hypothesis''. It describes generic behavior of different classes of systems, while deviations from its universal predictions allow to identify system specific properties. We use methods of RMT to analyze the cross-correlation matrix C of stock price changes [2] of the largest 1000 US companies. In addition to its scientific interest, the study of correlations between the returns of different stocks is also of practical relevance in quantifying the risk of a given stock portfolio. We find [3,4] that the statistics of most of the eigenvalues of the spectrum of C agree with the predictions of RMT, while there are deviations for some of the largest eigenvalues. We interpret these deviations as a system specific property, e.g. containing genuine information about correlations in the stock market. We demonstrate that C shares universal properties with the Gaussian orthogonal ensemble of random matrices. Furthermore, we analyze the eigenvectors of C through their inverse participation ratio and find eigenvectors with large ratios at both edges of the eigenvalue spectrum - a situation reminiscent of localization theory results. This work was done in collaboration with V. Plerou, P. Gopikrishnan, T. Guhr, L.A.N. Amaral, and H.E Stanley and is related to recent work of Laloux et al.. 1. T. Guhr, A. Müller Groeling, and H.A. Weidenmüller, ``Random Matrix Theories in Quantum Physics: Common Concepts'', Phys. Rep. 299, 190 (1998). 2. See, e.g. R.N. Mantegna and H.E. Stanley, Econophysics: Correlations and Complexity in Finance (Cambridge University Press, Cambridge, England, 1999). 3. V. Plerou, P. Gopikrishnan, B. Rosenow, L.A.N. Amaral, and H.E. Stanley, ``Universal and Nonuniversal Properties of Cross Correlations in Financial Time Series'', Phys. Rev. Lett. 83, 1471 (1999). 4. V. Plerou, P. Gopikrishnan, T. Guhr, B. Rosenow, L.A.N. Amaral, and H.E. Stanley, ``Random Matrix Theory

  5. Classical probabilistic realization of "Random Numbers Certified by Bell's Theorem"

    OpenAIRE

    Khrennikov, Andrei

    2015-01-01

    We question the commonly accepted statement that random numbers certified by Bell's theorem carry some special sort of randomness, so to say, quantum randomness or intrinsic randomness. We show that such numbers can be easily generated by classical random generators.

  6. Spectral statistics of random geometric graphs

    CERN Document Server

    Dettmann, Carl P; Knight, Georgie

    2016-01-01

    We study the spectrum of random geometric graphs using random matrix theory. We look at short range correlations in the level spacings via the nearest neighbour and next nearest neighbour spacing distribution and long range correlations via the spectral rigidity $\\Delta_3$ statistic. These correlations in the level spacings give information about localisation of eigenvectors, level of community structure and the level of randomness within the networks. We find that the spectral statistics of random geometric graphs fits the universality of random matrix theory. In particular, the short range correlations are very close to those found in the Gaussian orthogonal ensemble of random matrix theory. For long range correlations we find deviations from Gaussian orthogonal ensemble statistics towards Poisson. We compare with previous results for Erd\\H{o}s-R\\'{e}nyi, Barab{\\'a}si-Albert and Watts-Strogatz random graphs where similar random matrix theory universality has been found.

  7. Percon8 Algorithm for Random Number Generation

    Directory of Open Access Journals (Sweden)

    Dr. Mrs. Saylee Gharge

    2014-05-01

    Full Text Available In today’s technology savvy world, computer security holds a prime importance. Most computer security algorithms require some amount of random data for generating public and private keys, session keys or for other purposes. Random numbers are those numbers that occur in a sequence such that the future value of the sequence cannot be predicted based on present or past values. Random numbers find application in statistical analysis and probability theory. The many applications of randomness have led to the development of random number generating algorithms. These algorithms generate a sequence of random numbers either computationally or physically. In our proposed technique, we have implemented a random number generation algorithm combining two existing random number generation techniques viz. Mid square method and Linear Congruential Generator

  8. Self-correcting random number generator

    Energy Technology Data Exchange (ETDEWEB)

    Humble, Travis S.; Pooser, Raphael C.

    2016-09-06

    A system and method for generating random numbers. The system may include a random number generator (RNG), such as a quantum random number generator (QRNG) configured to self-correct or adapt in order to substantially achieve randomness from the output of the RNG. By adapting, the RNG may generate a random number that may be considered random regardless of whether the random number itself is tested as such. As an example, the RNG may include components to monitor one or more characteristics of the RNG during operation, and may use the monitored characteristics as a basis for adapting, or self-correcting, to provide a random number according to one or more performance criteria.

  9. Protocol for Shoulder function training reducing musculoskeletal pain in shoulder and neck: a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Mortensen Ole S

    2011-01-01

    Full Text Available Abstract Background Neck and shoulder complaints are common among employees in sedentary occupations characterized by intensive computer use. Such musculoskeletal pain - which is often associated with restricted range of motion and loss of muscle strength - is one of the most common conditions treated by physical therapists. The exact mechanism of neck pain is rarely revealed by clinical examination and the treatment has varied from passive rest to active treatments. Active treatments have often been divided into either training of the painful area or the surrounding musculature avoiding direct training of the painful area. Our study investigates the effect of the latter approach. Methods/Design A randomized controlled trial of 10 weeks duration is currently being conducted. Employed office workers with severe neck-shoulder pain are randomized to 3 × 20 min shoulder function training with training supervision or to a reference group receiving advice to stay physically active. Shoulder function training primarily focuses on the serratus anterior and lower trapezius muscle with only minimal activation the upper trapezius. An announcement was sent to the administrative section of the university including jobs characterized by intensive computer work. The first 100 positive replies entered the study. Among these inclusion criteria were pain intensity in the neck/shoulder of at least 3 on a 0-9 scale. Exclusion criteria were cardiovascular disease, trauma, hypertension, or serious chronic disease. Before and after the intervention period the participants replied to a questionnaire about musculoskeletal disorders and work disability, and underwent a standardized clinical examination of the neck and shoulder girdle. Further, on a weekly basis the participants log pain intensity of the neck and shoulder during the previous week. The primary outcome measure is pain in the neck and shoulders at week 10 based on the weekly pain registration and results

  10. Hypnosis as a treatment of chronic widespread pain in general practice: A randomized controlled pilot trial

    Directory of Open Access Journals (Sweden)

    Grøndahl Jan

    2008-09-01

    Full Text Available Abstract Background Hypnosis treatment in general practice is a rather new concept. This pilot study was performed to evaluate the effect of a standardized hypnosis treatment used in general practice for patients with chronic widespread pain (CWP. Methods The study was designed as a randomized control group-controlled study. Sixteen patients were randomized into a treatment group or a control group, each constituting eight patients. Seven patients in the treatment group completed the schedule. After the control period, five of the patients in the control group also received treatment, making a total of 12 patients having completed the treatment sessions. The intervention group went through a standardized hypnosis treatment with ten consecutive therapeutic sessions once a week, each lasting for about 30 minutes, focusing on ego-strengthening, relaxation, releasing muscular tension and increasing self-efficacy. A questionnaire was developed in order to calibrate the symptoms before and after the 10 weeks period, and the results were interpolated into a scale from 0 to 100, increasing numbers representing increasing suffering. Data were analyzed by means of T-tests. Results The treatment group improved from their symptoms, (change from 62.5 to 55.4, while the control group deteriorated, (change from 37.2 to 45.1, (p = 0,045. The 12 patients who completed the treatment showed a mean improvement from 51.5 to 41.6. (p = 0,046. One year later the corresponding result was 41.3, indicating a persisting improvement. Conclusion The study indicates that hypnosis treatment may have a positive effect on pain and quality of life for patients with chronic muscular pain. Considering the limited number of patients, more studies should be conducted to confirm the results. Trial Registration The study was registered in ClinicalTrials.gov and released 27.08.07 Reg nr NCT00521807 Approval Number: 05032001.

  11. Limit theorems for sequences of random trees

    OpenAIRE

    Balding, David; Ferrari, Pablo A.; Fraiman, Ricardo; Sued, Mariela

    2004-01-01

    We consider a random tree and introduce a metric in the space of trees to define the ``mean tree'' as the tree minimizing the average distance to the random tree. When the resulting metric space is compact we have laws of large numbers and central limit theorems for sequence of independent identically distributed random trees. As application we propose tests to check if two samples of random trees have the same law.

  12. Random matrix theory and wireless communications

    CERN Document Server

    Tulino, A M

    2014-01-01

    Random matrix theory has found many applications in physics, statistics and engineering since its inception. Although early developments were motivated by practical experimental problems, random matrices are now used in fields as diverse as Riemann hypothesis, stochastic differential equations, condensed matter physics, statistical physics, chaotic systems, numerical linear algebra, neural networks, multivariate statistics, information theory, signal processingand small-world networks.Random Matrix Theory and Wireless Communications is the first tutorial on random matrices which provides an ov

  13. A computer generator for randomly layered structures

    Institute of Scientific and Technical Information of China (English)

    YU Jia-shun; HE Zhen-hua

    2004-01-01

    An algorithm is introduced in this paper for the synthesis of randomly layered earth models. Under the assumption that the layering and the physical parameters for a layer are random variables with truncated normal distributions, random numbers sampled from the distributions can be used to construct the layered structure and determine physical parameters for the layers. To demonstrate its application, random models were synthesized for the modelling of seismic ground motion amplification of a site with uncertainties in its model parameters.

  14. AFFINE TRANSFORMATION IN RANDOM ITERATED FUNCTION SYSTEMS

    Institute of Scientific and Technical Information of China (English)

    熊勇; 史定华

    2001-01-01

    Random iterated function systems (IFSs) is discussed, which is one of the methods for fractal drawing. A certain figure can be reconstructed by a random IFS. One approach is presented to determine a new random IFS, that the figure reconstructed by the new random IFS is the image of the origin figure reconstructed by old IFS under a given affine transformation. Two particular examples are used to show this approach.

  15. The Nature of Simple Random Sampling

    OpenAIRE

    Mitra, S. K.; P.K. Pathak

    1984-01-01

    As an estimator of the population mean, the sample mean based only on the distinct units possesses a remarkable invariance property. Under three forms of simple random sampling, viz. simple random sampling without replacement (SRSWOR), simple random sampling with replacement (SRSWR), and fixed cost simple random sampling (SRSFC), it is admissible and unbiased; and asymptotically normally distributed if and only if the Erdos-Renyi-Hajek condition is satisfied. An important implication of this ...

  16. Random sources for cusped beams.

    Science.gov (United States)

    Li, Jia; Wang, Fei; Korotkova, Olga

    2016-08-01

    We introduce two novel classes of partially coherent sources whose degrees of coherence are described by the rectangular Lorentz-correlated Schell-model (LSM) and rectangular fractional multi-Gaussian-correlated Schell-model (FMGSM) functions. Based on the generalized Collins formula, analytical expressions are derived for the spectral density distributions of these beams propagating through a stigmatic ABCD optical system. It is shown that beams belonging to both classes form the spectral density apex that is much higher and sharper than that generated by the Gaussian Schell-model (GSM) beam with a comparable coherence state. We experimentally generate these beams by using a nematic, transmissive spatial light modulator (SLM) that serves as a random phase screen controlled by a computer. The experimental data is consistent with theoretical predictions. Moreover, it is illustrated that the FMGSM beam generated in our experiments has a better focusing capacity than the GSM beam with the same coherence state. The applications that can potentially benefit from the use of novel beams range from material surface processing, to communications and sensing through random media. PMID:27505746

  17. Function: A Randomized Clinical Trial

    Directory of Open Access Journals (Sweden)

    Shakuri Seyed Kazem

    2015-03-01

    Full Text Available Introduction: Prevention of pulmonary complications after coronary artery bypass graft is attended as a very important issue. The aim of this study was to evaluate the role of pulmonary rehabilitation before surgery for reducing the risk of pulmonary complications after surgery. Methods: In a randomized clinical trial, 60 patients undergoing heart surgery were randomly divided into two groups A and B. Chest physiotherapy was performed before and after surgery on group A patients however it was done on group B’s, only after surgery. Effects of preoperative pulmonary rehabilitation were compared between two groups, using spirometry and arterial blood gas (ABG. Results: Thirty nine males (65% and 21 females (35% with mean age of 8.10 ± 9.56 were analyzed.The mean differences were statistically significant for predicted forced vital capacity (FVC (CI95%:1.3 to 8.7 and Predicted Peak Flow indices (PEF (CI 95%: 1.9 to 9.4 of spirometry indicator,PCO2 index (of ABG parameter (CI 95%: 1.4 to 8.9 and mean oxygen saturation (mean Spo2 (CI 95%: 0.6 to 1.7 of ABG index in two groups. Conclusion: The performance of pulmonary rehabilitation program before surgery is recommended, as it may result in the reduction of complications of heart surgery.

  18. Randomized approximate nearest neighbors algorithm.

    Science.gov (United States)

    Jones, Peter Wilcox; Osipov, Andrei; Rokhlin, Vladimir

    2011-09-20

    We present a randomized algorithm for the approximate nearest neighbor problem in d-dimensional Euclidean space. Given N points {x(j)} in R(d), the algorithm attempts to find k nearest neighbors for each of x(j), where k is a user-specified integer parameter. The algorithm is iterative, and its running time requirements are proportional to T·N·(d·(log d) + k·(d + log k)·(log N)) + N·k(2)·(d + log k), with T the number of iterations performed. The memory requirements of the procedure are of the order N·(d + k). A by-product of the scheme is a data structure, permitting a rapid search for the k nearest neighbors among {x(j)} for an arbitrary point x ∈ R(d). The cost of each such query is proportional to T·(d·(log d) + log(N/k)·k·(d + log k)), and the memory requirements for the requisite data structure are of the order N·(d + k) + T·(d + N). The algorithm utilizes random rotations and a basic divide-and-conquer scheme, followed by a local graph search. We analyze the scheme's behavior for certain types of distributions of {x(j)} and illustrate its performance via several numerical examples.

  19. INVARIANT RANDOM APPROXIMATION IN NONCONVEX DOMAIN

    Directory of Open Access Journals (Sweden)

    R. Shrivastava

    2012-05-01

    Full Text Available Random fixed point results in the setup of compact and weakly compact domain of Banach spaces which is not necessary starshaped have been obtained in the present work. Invariant random approximation results have also been determined asits application. In this way, random version of invariant approximation results due toMukherjee and Som [13] and Singh [17] have been given.

  20. Source-Independent Quantum Random Number Generation

    Science.gov (United States)

    Cao, Zhu; Zhou, Hongyi; Yuan, Xiao; Ma, Xiongfeng

    2016-01-01

    Quantum random number generators can provide genuine randomness by appealing to the fundamental principles of quantum mechanics. In general, a physical generator contains two parts—a randomness source and its readout. The source is essential to the quality of the resulting random numbers; hence, it needs to be carefully calibrated and modeled to achieve information-theoretical provable randomness. However, in practice, the source is a complicated physical system, such as a light source or an atomic ensemble, and any deviations in the real-life implementation from the theoretical model may affect the randomness of the output. To close this gap, we propose a source-independent scheme for quantum random number generation in which output randomness can be certified, even when the source is uncharacterized and untrusted. In our randomness analysis, we make no assumptions about the dimension of the source. For instance, multiphoton emissions are allowed in optical implementations. Our analysis takes into account the finite-key effect with the composable security definition. In the limit of large data size, the length of the input random seed is exponentially small compared to that of the output random bit. In addition, by modifying a quantum key distribution system, we experimentally demonstrate our scheme and achieve a randomness generation rate of over 5 ×103 bit /s .

  1. Variational Infinite Hidden Conditional Random Fields

    NARCIS (Netherlands)

    Bousmalis, Konstantinos; Zafeiriou, Stefanos; Morency, Louis-Philippe; Pantic, Maja; Ghahramani, Zoubin

    2015-01-01

    Hidden conditional random fields (HCRFs) are discriminative latent variable models which have been shown to successfully learn the hidden structure of a given classification problem. An Infinite hidden conditional random field is a hidden conditional random field with a countably infinite number of

  2. Numerical studies of planar closed random walks

    International Nuclear Information System (INIS)

    Lattice numerical simulations for planar closed random walks and their winding sectors are presented. The frontiers of the random walks and of their winding sectors have a Hausdorff dimension dH = 4/3. However, when properly defined by taking into account the inner 0-winding sectors, the frontiers of the random walks have a Hausdorff dimension dH≈1.77

  3. Randomness in Sequence Evolution Increases over Time.

    Science.gov (United States)

    Wang, Guangyu; Sun, Shixiang; Zhang, Zhang

    2016-01-01

    The second law of thermodynamics states that entropy, as a measure of randomness in a system, increases over time. Although studies have investigated biological sequence randomness from different aspects, it remains unknown whether sequence randomness changes over time and whether this change consists with the second law of thermodynamics. To capture the dynamics of randomness in molecular sequence evolution, here we detect sequence randomness based on a collection of eight statistical random tests and investigate the randomness variation of coding sequences with an application to Escherichia coli. Given that core/essential genes are more ancient than specific/non-essential genes, our results clearly show that core/essential genes are more random than specific/non-essential genes and accordingly indicate that sequence randomness indeed increases over time, consistent well with the second law of thermodynamics. We further find that an increase in sequence randomness leads to increasing randomness of GC content and longer sequence length. Taken together, our study presents an important finding, for the first time, that sequence randomness increases over time, which may provide profound insights for unveiling the underlying mechanisms of molecular sequence evolution. PMID:27224236

  4. Random packing of colloids and granular matter

    NARCIS (Netherlands)

    Wouterse, A.

    2008-01-01

    This thesis deals with the random packing of colloids and granular matter. A random packing is a stable disordered collection of touching particles, without long-range positional and orientational order. Experimental random packings of particles with the same shape but made of different materials sh

  5. Lyapunov exponents for continuous random transformations

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    In this paper, the concept of Lyapunov exponent is generalized to random transformations that are not necessarily differentiable. For a class of random repellers and of random hyperbolic sets obtained via small perturbations of deterministic ones respectively, the new exponents are shown to coincide with the classical ones.

  6. Parabolic Anderson Model in a Dynamic Random Environment: Random Conductances

    Science.gov (United States)

    Erhard, D.; den Hollander, F.; Maillard, G.

    2016-06-01

    The parabolic Anderson model is defined as the partial differential equation ∂ u( x, t)/ ∂ t = κ Δ u( x, t) + ξ( x, t) u( x, t), x ∈ ℤ d , t ≥ 0, where κ ∈ [0, ∞) is the diffusion constant, Δ is the discrete Laplacian, and ξ is a dynamic random environment that drives the equation. The initial condition u( x, 0) = u 0( x), x ∈ ℤ d , is typically taken to be non-negative and bounded. The solution of the parabolic Anderson equation describes the evolution of a field of particles performing independent simple random walks with binary branching: particles jump at rate 2 d κ, split into two at rate ξ ∨ 0, and die at rate (- ξ) ∨ 0. In earlier work we looked at the Lyapunov exponents λ p(κ ) = limlimits _{tto ∞} 1/t log {E} ([u(0,t)]p)^{1/p}, quad p in {N} , qquad λ 0(κ ) = limlimits _{tto ∞} 1/2 log u(0,t). For the former we derived quantitative results on the κ-dependence for four choices of ξ : space-time white noise, independent simple random walks, the exclusion process and the voter model. For the latter we obtained qualitative results under certain space-time mixing conditions on ξ. In the present paper we investigate what happens when κΔ is replaced by Δ𝓚, where 𝓚 = {𝓚( x, y) : x, y ∈ ℤ d , x ˜ y} is a collection of random conductances between neighbouring sites replacing the constant conductances κ in the homogeneous model. We show that the associated annealed Lyapunov exponents λ p (𝓚), p ∈ ℕ, are given by the formula λ p({K} ) = {sup} {λ p(κ ) : κ in {Supp} ({K} )}, where, for a fixed realisation of 𝓚, Supp(𝓚) is the set of values taken by the 𝓚-field. We also show that for the associated quenched Lyapunov exponent λ 0(𝓚) this formula only provides a lower bound, and we conjecture that an upper bound holds when Supp(𝓚) is replaced by its convex hull. Our proof is valid for three classes of reversible ξ, and for all 𝓚

  7. Random matrix techniques in quantum information theory

    Energy Technology Data Exchange (ETDEWEB)

    Collins, Benoît, E-mail: collins@math.kyoto-u.ac.jp [Department of Mathematics, Kyoto University, Kyoto 606-8502 (Japan); Département de Mathématique et Statistique, Université d’Ottawa, 585 King Edward, Ottawa, Ontario K1N6N5 (Canada); CNRS, Lyon (France); Nechita, Ion, E-mail: nechita@irsamc.ups-tlse.fr [Zentrum Mathematik, M5, Technische Universität München, Boltzmannstrasse 3, 85748 Garching (Germany); Laboratoire de Physique Théorique, CNRS, IRSAMC, Université de Toulouse, UPS, F-31062 Toulouse (France)

    2016-01-15

    The purpose of this review is to present some of the latest developments using random techniques, and in particular, random matrix techniques in quantum information theory. Our review is a blend of a rather exhaustive review and of more detailed examples—coming mainly from research projects in which the authors were involved. We focus on two main topics, random quantum states and random quantum channels. We present results related to entropic quantities, entanglement of typical states, entanglement thresholds, the output set of quantum channels, and violations of the minimum output entropy of random channels.

  8. Randomized Binary Consensus with Faulty Agents

    Directory of Open Access Journals (Sweden)

    Alexander Gogolev

    2014-05-01

    Full Text Available This paper investigates self-organizing binary majority consensus disturbed by faulty nodes with random and persistent failure. We study consensus in ordered and random networks with noise, message loss and delays. Using computer simulations, we show that: (1 explicit randomization by noise, message loss and topology can increase robustness towards faulty nodes; (2 commonly-used faulty nodes with random failure inhibit consensus less than faulty nodes with persistent failure; and (3 in some cases, such randomly failing faulty nodes can even promote agreement.

  9. Decompounding random sums: A nonparametric approach

    DEFF Research Database (Denmark)

    Hansen, Martin Bøgsted; Pitts, Susan M.

    Observations from sums of random variables with a random number of summands, known as random, compound or stopped sums arise within many areas of engineering and science. Quite often it is desirable to infer properties of the distribution of the terms in the random sum. In the present paper we...... review a number of applications and consider the nonlinear inverse problem of inferring the cumulative distribution function of the components in the random sum. We review the existing literature on non-parametric approaches to the problem. The models amenable to the analysis are generalized considerably...

  10. Various Expressions for Modulus of Random Convexity

    Institute of Scientific and Technical Information of China (English)

    Xiao Lin ZENG

    2013-01-01

    We first prove various kinds of expressions for modulus of random convexity by using an Lo(F,R)-valued function's intermediate value theorem and the well known Hahn-Banach theorem for almost surely bounded random linear functionals,then establish some basic properties including continuity for modulus of random convexity.In particular,we express the modulus of random convexity of a special random normed module Lo(F,X) derived from a normed space X by the classical modulus of convexity of X.

  11. Bit recycling for scaling random number generators

    OpenAIRE

    Mennucci, Andrea C. G.

    2010-01-01

    Many Random Number Generators (RNG) are available nowadays; they are divided in two categories, hardware RNG, that provide "true" random numbers, and algorithmic RNG, that generate pseudo random numbers (PRNG). Both types usually generate random numbers (X_n) as independent uniform samples in a range 0...2^b-1, with b = 8, 16, 32 or b = 64. In applications, it is instead sometimes desirable to draw random numbers as independent uniform samples (Y_n) in a range 1, . . . M, where moreover M may...

  12. Random Numbers in Scientific Computing: An Introduction

    CERN Document Server

    Katzgraber, Helmut G

    2010-01-01

    Random numbers play a crucial role in science and industry. Many numerical methods require the use of random numbers, in particular the Monte Carlo method. Therefore it is of paramount importance to have efficient random number generators. The differences, advantages and disadvantages of true and pseudo random number generators are discussed with an emphasis on the intrinsic details of modern and fast pseudo random number generators. Furthermore, standard tests to verify the quality of the random numbers produced by a given generator are outlined. Finally, standard scientific libraries with built-in generators are presented, as well as different approaches to generate nonuniform random numbers. Potential problems that one might encounter when using large parallel machines are discussed.

  13. Branching diffusions in random environment

    CERN Document Server

    Böinghoff, Christian

    2011-01-01

    We consider the diffusion approximation of branching processes in random environment (BPREs). This diffusion approximation is similar to and mathematically more tractable than BPREs. We obtain the exact asymptotic behavior of the survival probability. As in the case of BPREs, there is a phase transition in the subcritical regime due to different survival opportunities. In addition, we characterize the process conditioned to never go extinct and establish a backbone construction. In the strongly subcritical regime, mean offspring numbers are increased but still subcritical in the process conditioned to never go extinct. Here survival is solely due to an immortal individual, whose offspring are the ancestors of additional families. In the weakly subcritical regime, the mean offspring number is supercritical in the process conditioned to never go extinct. Thus this process survives with positive probability even if there was no immortal individual.

  14. Dynamic random channel reservation protocol

    Institute of Scientific and Technical Information of China (English)

    Ren Yanying; Zhang Wenjun; Yu Songyu

    2005-01-01

    Demand assignment MAC protocols have been used widely in wireless networks. It can effectively utilize wireless bandwidth. Some strategies can be used by demand assignment MAC protocols to further improve their efficiency. The concept of transmit probability is introduced. This concept allows a request slot to be assigned to many different traffic classes at the same time. Based on it, the dynamic random channel reservation (DRCR) protocol is proposed. The DRCR protocol operates dynamically by observing the traffic conditions. It uses information about the recent traffic conditions to assign transmit probability with which an mobile station can select request slots with lower traffic. The performance of DRCR is evaluated and compared with RSCA. The results show that DRCR is more stable than RSCA, it offers shorter delays of requests than RSCA and can relieve heavily stressed traffic classes faster than RSCA.

  15. Driven Random Field Ising Model:

    Science.gov (United States)

    Shukla, Prabodh

    The random field Ising Model (RFIM) driven by a slowly varying uniform external field at zero temperature provides a caricature of several threshold activated systems. In this model, the non-equilibrium response of the system can be obtained analytically in one dimension as well as on a Bethe lattice if the initial state of the system has all spins aligned parallel to each other. We consider ferromagnetic as well as anti-ferromagnetic interactions. The ferromagnetic model exhibits avalanches and non-equilibrium critical behavior. The anti-ferromagnetic model is marked by the absence of these features. The ferromagnetic model is Abelian, and the anti-ferromagnetic model is non-Abelian. Theoretical approaches based on the probabilistic method are discussed in the two cases, and illustrated by deriving some basic results.

  16. Randomness and Earth climate variability

    CERN Document Server

    Levinshtein, Michael E; Dmitriev, Alexander P; Shmakov, Pavel M

    2015-01-01

    Paleo-Sciences including palaeoclimatology and palaeoecology have accumulated numerous records related to climatic changes. The researchers have usually tried to identify periodic and quasi-periodic processes in these paleoscientific records. In this paper, we show that this analysis is incomplete. As follows from our results, random processes, namely processes with a single-time-constant (noise with a Lorentzian noise spectrum), play a very important and, perhaps, a decisive role in numerous natural phenomena. For several of very important natural phenomena the characteristic time constants are very similar and equal to (5-8)x10^3 years. However, this value is not universal. For example, the spectral density fluctuations of the atmospheric radiocarbon 14C are characterized by a Lorentzian with time constant 300 years. The frequency dependence of spectral density fluctuations for benthic 18O records contains two Lorentzians with time constans 8000 years and > 105 years.

  17. Random equations in nilpotent groups

    CERN Document Server

    Gilman, Robert; Romankov, Vitalii

    2011-01-01

    In this paper we study satisfiability of random equations in an infinite finitely generated nilpotent group G. We show that the set SAT(G,k) of all equations in k > 1 variables over G which are satisfiable in G has an intermediate asymptotic density in the space of all equations in k variables over G. When G is a free abelian group of finite rank, we compute this density precisely; otherwise we give some non-trivial upper and lower bounds. For k = 1 the set SAT(G,k) is negligible. Usually the asymptotic densities of interesting sets in groups are either zero or one. The results of this paper provide new examples of algebraically significant sets of intermediate asymptotic density.

  18. Jellyfish: Networking Data Centers Randomly

    CERN Document Server

    Singla, Ankit; Popa, Lucian; Godfrey, P Brighten

    2011-01-01

    Industry experience indicates that the ability to incrementally expand data centers is essential. However, existing high-bandwidth network designs have rigid structure that interferes with incremental expansion. We present Jellyfish, a high-capacity network interconnect, which, by adopting a random graph topology, yields itself naturally to incremental expansion. Somewhat surprisingly, Jellyfish is more cost-efficient than a fat-tree: A Jellyfish interconnect built using the same equipment as a fat-tree, supports as many as 25% more servers at full capacity at the scale of a few thousand nodes, and this advantage improves with scale. Jellyfish also allows great flexibility in building networks with different degrees of oversubscription. However, Jellyfish's unstructured design brings new challenges in routing, physical layout, and wiring. We describe and evaluate approaches that resolve these challenges effectively, indicating that Jellyfish could be deployed in today's data centers.

  19. Quantum randomness and free will

    CERN Document Server

    Nayakar, Chetan S Mandayam

    2010-01-01

    Both deterministic and indeterministic physical laws are incompatible with control by genuine (non-illusory) free will. We propose that an indeterministic dynamics can be $weakly$ compatible with free will (FW), whereby the latter acts by altering the probability distribution over allowed outcomes. In the quantum physical world, such a FW can collapse the wave function, introducing deviations from the Born rule. In principle, this deviation would stand in conflict with both special relativity and (a variant of) the Strong Church-Turing thesis, implying that the brain may be an arena of exotic, non-standard physics. However, in practice, these deviations would not be directly or easily observable, because they occur in sub-neuronal superpositions in the brain, where they would be shrouded in random measurement errors, noise and statistical fluctuations. Our result elucidates the difference between the FW of human observers and that of observed particles in the Free Will Theorem. This difference is a basic reas...

  20. Ergodic theory, randomness, and "chaos".

    Science.gov (United States)

    Ornstein, D S

    1989-01-13

    Ergodic theory is the theory of the long-term statistical behavior of dynamical systems. The baker's transformation is an object of ergodic theory that provides a paradigm for the possibility of deterministic chaos. It can now be shown that this connection is more than an analogy and that at some level of abstraction a large number of systems governed by Newton's laws are the same as the baker's transformation. Going to this level of abstraction helps to organize the possible kinds of random behavior. The theory also gives new concrete results. For example, one can show that the same process could be produced by a mechanism governed by Newton's laws or by a mechanism governed by coin tossing. It also gives a statistical analog of structural stability.

  1. The quenched invariance principle for random walks in random environments admitting a bounded cycle representation

    OpenAIRE

    Deuschel, Jean-Dominique; Kösters, Holger

    2008-01-01

    We derive a quenched invariance principle for random walks in random environments whose transition probabilities are defined in terms of weighted cycles of bounded length. To this end, we adapt the proof for random walks among random conductances by Sidoravicius and Sznitman (Probab. Theory Related Fields 129 (2004) 219--244) to the non-reversible setting.

  2. THE RANDOM SHIFT SET AND RANDOM SUB-SELF-SIMILAR SET

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    First of all the authors introduce the concepts of random sub-self-similar set and random shift set and then construct the random sub-self-similar set by a random shift set and a collection of statistical contraction operators.

  3. A RANDOM FIXED POINT ITERATION FOR THREE RANDOM OPERATORS ON UNIFORMLY CONVEX BANACH SPACES

    Institute of Scientific and Technical Information of China (English)

    Binayak S. Choudhury

    2003-01-01

    In the present paper we introduce a random iteration scheme for three random operators defined on a closed and convex subset of a uniformly convex Banach space and prove its convergence to a common fixed point of three random operators. The result is also an extension of a known theorem in the corresponding non-random case.

  4. Excitation of localized modes and mechanism of random lasing forming in random media

    Institute of Scientific and Technical Information of China (English)

    WANG Hong; LIU Jinsong; WANG Kejia; HAN Yanling

    2006-01-01

    Laser phenomena in random media have been studied based on the localized theory for lightwave in random media. The relationship between random lasing modes and localized modes has been investigated by directly solving Maxwell equations numerically via the finite difference time domain method. The spatial distribution and the spectra of localized modes are obtained for both passive and active random media. The results show that random lasing modes directly originate from the localized modes inside the random medium. In the presence of gain, any one of the localized modes can be amplified and can serve as random lasing mode.

  5. Functional Magnetic Resonance Imaging Neurofeedback-guided Motor Imagery Training and Motor Training for Parkinson’s Disease: Randomized Trial

    Science.gov (United States)

    Subramanian, Leena; Morris, Monica Busse; Brosnan, Meadhbh; Turner, Duncan L.; Morris, Huw R.; Linden, David E. J.

    2016-01-01

    Objective: Real-time functional magnetic resonance imaging (rt-fMRI) neurofeedback (NF) uses feedback of the patient’s own brain activity to self-regulate brain networks which in turn could lead to a change in behavior and clinical symptoms. The objective was to determine the effect of NF and motor training (MOT) alone on motor and non-motor functions in Parkinson’s Disease (PD) in a 10-week small Phase I randomized controlled trial. Methods: Thirty patients with Parkinson’s disease (PD; Hoehn and Yahr I-III) and no significant comorbidity took part in the trial with random allocation to two groups. Group 1 (NF: 15 patients) received rt-fMRI-NF with MOT. Group 2 (MOT: 15 patients) received MOT alone. The primary outcome measure was the Movement Disorder Society—Unified PD Rating Scale-Motor scale (MDS-UPDRS-MS), administered pre- and post-intervention “off-medication”. The secondary outcome measures were the “on-medication” MDS-UPDRS, the PD Questionnaire-39, and quantitative motor assessments after 4 and 10 weeks. Results: Patients in the NF group were able to upregulate activity in the supplementary motor area (SMA) by using motor imagery. They improved by an average of 4.5 points on the MDS-UPDRS-MS in the “off-medication” state (95% confidence interval: −2.5 to −6.6), whereas the MOT group improved only by 1.9 points (95% confidence interval +3.2 to −6.8). The improvement in the intervention group meets the minimal clinically important difference which is also on par with other non-invasive therapies such as repetitive Transcranial Magnetic Stimulation (rTMS). However, the improvement did not differ significantly between the groups. No adverse events were reported in either group. Interpretation: This Phase I study suggests that NF combined with MOT is safe and improves motor symptoms immediately after treatment, but larger trials are needed to explore its superiority over active control conditions. PMID:27375451

  6. Participation in a 10-week course of yoga improves behavioural control and decreases psychological distress in a prison population

    NARCIS (Netherlands)

    Bilderbeck, A.C.; Farias, M.; Brazil, I.A.; Jakobowitz, S.; Wikholm, C.

    2013-01-01

    Background Yoga and meditation have been shown to be effective in alleviating symptoms of depression and anxiety in healthy volunteers and psychiatric populations. Recent work has also indicated that yoga can improve cognitive-behavioural performance and control. Although there have been no controll

  7. Participation in a 10-week course of yoga improves behavioural control and decreases psychological distress in a prison population

    OpenAIRE

    Bilderbeck, A.C.; Farias, M.; Brazil, I.A.; Jakobowitz, S.; Wikholm, C.

    2013-01-01

    Background Yoga and meditation have been shown to be effective in alleviating symptoms of depression and anxiety in healthy volunteers and psychiatric populations. Recent work has also indicated that yoga can improve cognitive-behavioural performance and control. Although there have been no controlled studies of the effects of yoga in a prison population, we reasoned that yoga could have beneficial effects in a setting where psychosocial functioning is often low, and the frequency of impulsiv...

  8. The influence of floor type before and after 10 weeks of age on osteochondrosis in growing gilts

    OpenAIRE

    Koning, D.B.; van Grevenhof, E.M.; Laurenssen, B.F.A.; Weeren, P.R. van; Hazeleger, W.; Kemp, B.

    2014-01-01

    Osteochondrosis (OC) is a degenerative joint condition developing in a short time frame in young growing gilts that may cause lameness at an older age, affecting welfare and leading to premature culling of breeding sows. Causes of OC are multifactorial including both genetic and environmental factors. Floor type has been suggested to affect OC prevalence and effects might be age dependent during the rearing period. The aim of this study was to investigate possible age-dependent effects of flo...

  9. Effects of consuming fructose- or glucose-sweetened beverages for 10 weeks on lipids, insulin sensitivity and adiposity

    Science.gov (United States)

    Animal studies have documented that, compared with glucose, dietary fructose promotes dyslipidemia and insulin resistance. Experimental evidence that fructose consumption in humans promotes dyslipidemia and insulin resistance compared with glucose consumption has been equivocal. We tested the hypoth...

  10. The influence of floor type before and after 10 weeks of age on osteochondrosis in growing gilts.

    Science.gov (United States)

    de Koning, D B; van Grevenhof, E M; Laurenssen, B F A; van Weeren, P R; Hazeleger, W; Kemp, B

    2014-08-01

    Osteochondrosis (OC) is a degenerative joint condition developing in a short time frame in young growing gilts that may cause lameness at an older age, affecting welfare and leading to premature culling of breeding sows. Causes of OC are multifactorial including both genetic and environmental factors. Floor type has been suggested to affect OC prevalence and effects might be age dependent during the rearing period. The aim of this study was to investigate possible age-dependent effects of floor type, conventional concrete partially slatted versus wood shavings as deep bedding, on OC prevalence in gilts (Dutch Large White × Dutch Landrace) at slaughter (24 wk of age; 106.5 [14.7 SD] kg of BW). At weaning (4 wk of age; 6.9 [1.3 SD] kg of BW), 212 gilts were subjected to 1 of 4 flooring regimens. Gilts were either subjected to a conventional floor from weaning until slaughter (CC), wood shavings as bedding from weaning until slaughter (WW), a conventional floor from weaning until 10 wk of age after which gilts were switched to wood shavings as bedding (CW), or wood shavings as bedding from weaning until 10 wk of age after which gilts were switched to a conventional floor (WC). After slaughter the elbow, hock, and knee joints were macroscopically examined for OC and scored on a 5 point scale where 0 indicates no OC and 4 indicates the severest form of OC. There was no significant difference (P > 0.4) between treatments on the overall OC prevalence for any joint assessed or at the animal level (all joints combined). At the animal level, however, gilts had greater odds to have OC scores 3 and 4 in the CW treatment (odds ratios [OR] = 2.3; P = 0.05), WC treatment (OR = 2.6; P = 0.02), and WW treatment (OR = 3.7; P floor types on overall OC prevalence. However, wood shavings as bedding seems to increase the odds for severe OC and might affect animal welfare in the long term.

  11. The influence of floor type before and after 10 weeks of age on osteochondrosis in growing gilts

    NARCIS (Netherlands)

    de Koning, D B; van Grevenhof, E M; Laurenssen, B F A; van Weeren, P R; Hazeleger, W; Kemp, B

    2014-01-01

    Osteochondrosis (OC) is a degenerative joint condition developing in a short time frame in young growing gilts that may cause lameness at an older age, affecting welfare and leading to premature culling of breeding sows. Causes of OC are multifactorial including both genetic and environmental factor

  12. The influence of dietary restriction before and after 10 weeks of age on osteochondrosis in growing gilts

    NARCIS (Netherlands)

    Koning, de D.B.; Grevenhof, van E.M.; Laurenssen, B.F.A.; Weeren, van P.R.; Hazeleger, W.; Kemp, B.

    2013-01-01

    Osteochondrosis (OC) is one of the main causes of leg weakness causing premature culling in breeding sows and develops in a short time frame in young growing gilts. Dietary restriction may have different effects on OC prevalence depending on the age of the gilts. The aim of this study is to investig

  13. Probability, random variables, and random processes theory and signal processing applications

    CERN Document Server

    Shynk, John J

    2012-01-01

    Probability, Random Variables, and Random Processes is a comprehensive textbook on probability theory for engineers that provides a more rigorous mathematical framework than is usually encountered in undergraduate courses. It is intended for first-year graduate students who have some familiarity with probability and random variables, though not necessarily of random processes and systems that operate on random signals. It is also appropriate for advanced undergraduate students who have a strong mathematical background. The book has the following features: Several app

  14. Semi-device-independent randomness expansion with partially free random sources using 3 →1 quantum random access code

    Science.gov (United States)

    Zhou, Yu-Qian; Gao, Fei; Li, Dan-Dan; Li, Xin-Hui; Wen, Qiao-Yan

    2016-09-01

    We have proved that new randomness can be certified by partially free sources using 2 →1 quantum random access code (QRAC) in the framework of semi-device-independent (SDI) protocols [Y.-Q. Zhou, H.-W. Li, Y.-K. Wang, D.-D. Li, F. Gao, and Q.-Y. Wen, Phys. Rev. A 92, 022331 (2015), 10.1103/PhysRevA.92.022331]. To improve the effectiveness of the randomness generation, here we propose the SDI randomness expansion using 3 →1 QRAC and obtain the corresponding classical and quantum bounds of the two-dimensional quantum witness. Moreover, we get the condition which should be satisfied by the partially free sources to successfully certify new randomness, and the analytic relationship between the certified randomness and the two-dimensional quantum witness violation.

  15. Error Threshold of Fully Random Eigen Model

    Science.gov (United States)

    Li, Duo-Fang; Cao, Tian-Guang; Geng, Jin-Peng; Qiao, Li-Hua; Gu, Jian-Zhong; Zhan, Yong

    2015-01-01

    Species evolution is essentially a random process of interaction between biological populations and their environments. As a result, some physical parameters in evolution models are subject to statistical fluctuations. In this work, two important parameters in the Eigen model, the fitness and mutation rate, are treated as Gaussian distributed random variables simultaneously to examine the property of the error threshold. Numerical simulation results show that the error threshold in the fully random model appears as a crossover region instead of a phase transition point, and as the fluctuation strength increases the crossover region becomes smoother and smoother. Furthermore, it is shown that the randomization of the mutation rate plays a dominant role in changing the error threshold in the fully random model, which is consistent with the existing experimental data. The implication of the threshold change due to the randomization for antiviral strategies is discussed.

  16. Sequential monitoring with conditional randomization tests

    CERN Document Server

    Plamadeala, Victoria; 10.1214/11-AOS941

    2012-01-01

    Sequential monitoring in clinical trials is often employed to allow for early stopping and other interim decisions, while maintaining the type I error rate. However, sequential monitoring is typically described only in the context of a population model. We describe a computational method to implement sequential monitoring in a randomization-based context. In particular, we discuss a new technique for the computation of approximate conditional tests following restricted randomization procedures and then apply this technique to approximate the joint distribution of sequentially computed conditional randomization tests. We also describe the computation of a randomization-based analog of the information fraction. We apply these techniques to a restricted randomization procedure, Efron's [Biometrika 58 (1971) 403--417] biased coin design. These techniques require derivation of certain conditional probabilities and conditional covariances of the randomization procedure. We employ combinatoric techniques to derive t...

  17. Random Phases and Energy Dispersion

    Institute of Scientific and Technical Information of China (English)

    刘全慧; 刘天贵; 班卫全

    2003-01-01

    Using 2N + 1 successive stationary states centred at nth, we construct a rectangular wavepacket in which the stationary states are superimposed with the equal weight √2N + 1. With the requirement of the wavepacket to be a quasi-classical state, the number N is determined by minimizing the uncertainty △x△p. Since the stationary state can only be determined to within an arbitrary multiplicative complex phase factor of unit magnitude, a number of N is obtained as a set of the phases are given. For a harmonic oscillator, when all of the phase factors are essentially the same, we have N ≈ [61/3n2/3] with [x] signifying the integral part of positive number x. When every phase in the phase factors is given by a random number generated in a closed interval [0, 2π] and when n ≥ 10, the probability of appearance of N is roughly 1/2N when N = 1 to 7, and does not exceed 0.01 whenN ≥ 8.

  18. Efficient robust conditional random fields.

    Science.gov (United States)

    Song, Dongjin; Liu, Wei; Zhou, Tianyi; Tao, Dacheng; Meyer, David A

    2015-10-01

    Conditional random fields (CRFs) are a flexible yet powerful probabilistic approach and have shown advantages for popular applications in various areas, including text analysis, bioinformatics, and computer vision. Traditional CRF models, however, are incapable of selecting relevant features as well as suppressing noise from noisy original features. Moreover, conventional optimization methods often converge slowly in solving the training procedure of CRFs, and will degrade significantly for tasks with a large number of samples and features. In this paper, we propose robust CRFs (RCRFs) to simultaneously select relevant features. An optimal gradient method (OGM) is further designed to train RCRFs efficiently. Specifically, the proposed RCRFs employ the l1 norm of the model parameters to regularize the objective used by traditional CRFs, therefore enabling discovery of the relevant unary features and pairwise features of CRFs. In each iteration of OGM, the gradient direction is determined jointly by the current gradient together with the historical gradients, and the Lipschitz constant is leveraged to specify the proper step size. We show that an OGM can tackle the RCRF model training very efficiently, achieving the optimal convergence rate [Formula: see text] (where k is the number of iterations). This convergence rate is theoretically superior to the convergence rate O(1/k) of previous first-order optimization methods. Extensive experiments performed on three practical image segmentation tasks demonstrate the efficacy of OGM in training our proposed RCRFs.

  19. Random stress and Omori's law

    CERN Document Server

    Kagan, Yan Y

    2010-01-01

    We consider two statistical regularities that were used to explain Omori's law of the aftershock rate decay: the Levy and Inverse Gaussian (IGD) distributions. These distributions are thought to describe stress behavior influenced by various random factors: post-earthquake stress time history is described by a Brownian motion. Both distributions decay to zero for time intervals close to zero. But this feature contradicts the high immediate aftershock level according to Omori's law. We propose that these statistical distributions are influenced by the power-law stress distribution near the earthquake focal zone and we derive new distributions as a mixture of power-law stress with the exponent psi and Levy as well as IGD distributions. Such new distributions describe the resulting inter-earthquake time intervals and closely resemble Omori's law. The new Levy distribution has a pure power-law form with the exponent -(1+psi/2) and the mixed IGD has two exponents: the same as Levy for small time intervals and -(1+...

  20. DUAL RANDOM MODEL OF INCREASING ANNUITY

    Institute of Scientific and Technical Information of China (English)

    HeWenjiong; ZhangYi

    2001-01-01

    The dual random models about the life insurance and social pension insurance have received considerable attention in the recent articles on actuarial theory and applications. This paper discusses a general kind of increasing annuity based on its force of interest accumulationfunction as a general random process. The dual random model of the present value of the benefits of the increasing annuity has been set, and their moments have been calculated under certainconditions.

  1. Numerical studies of planar closed random walks

    OpenAIRE

    Desbois, Jean; Ouvry, Stephane

    2008-01-01

    Lattice numerical simulations for planar closed random walks and their winding sectors are presented. The frontiers of the random walks and of their winding sectors have a Hausdorff dimension $d_H=4/3$. However, when properly defined by taking into account the inner 0-winding sectors, the frontiers of the random walks have a Hausdorff dimension $d_H\\approx 1.77$.

  2. Private randomness expansion with untrusted devices

    Energy Technology Data Exchange (ETDEWEB)

    Colbeck, Roger; Kent, Adrian, E-mail: rcolbeck@perimeterinstitute.ca, E-mail: a.p.a.kent@damtp.cam.ac.uk [Perimeter Institute for Theoretical Physics, 31 Caroline Street North, Waterloo, ON N2L 2Y5 (Canada)

    2011-03-04

    Randomness is an important resource for many applications, from gambling to secure communication. However, guaranteeing that the output from a candidate random source could not have been predicted by an outside party is a challenging task, and many supposedly random sources used today provide no such guarantee. Quantum solutions to this problem exist, for example a device which internally sends a photon through a beamsplitter and observes on which side it emerges, but, presently, such solutions require the user to trust the internal workings of the device. Here, we seek to go beyond this limitation by asking whether randomness can be generated using untrusted devices-even ones created by an adversarial agent-while providing a guarantee that no outside party (including the agent) can predict it. Since this is easily seen to be impossible unless the user has an initially private random string, the task we investigate here is private randomness expansion. We introduce a protocol for private randomness expansion with untrusted devices which is designed to take as input an initially private random string and produce as output a longer private random string. We point out that private randomness expansion protocols are generally vulnerable to attacks that can render the initial string partially insecure, even though that string is used only inside a secure laboratory; our protocol is designed to remove this previously unconsidered vulnerability by privacy amplification. We also discuss extensions of our protocol designed to generate an arbitrarily long random string from a finite initially private random string. The security of these protocols against the most general attacks is left as an open question.

  3. An isomorphism theorem for random interlacements

    OpenAIRE

    Sznitman, Alain-Sol

    2011-01-01

    We consider continuous-time random interlacements on a transient weighted graph. We prove an identity in law relating the field of occupation times of random interlacements at level u to the Gaussian free field on the weighted graph. This identity is closely linked to the generalized second Ray-Knight theorem, and uniquely determines the law of occupation times of random interlacements at level u.

  4. Random 'choices' and the locality loophole

    OpenAIRE

    Pironio, Stefano

    2015-01-01

    It has been claimed that to close the locality loophole in a Bell experiment, random numbers of quantum origin should be used for selecting the measurement settings. This is how it has been implemented in all recent Bell experiment addressing this loophole. I point out in this note that quantum random number generators are unnecessary for such experiments and that a Bell experiment with a pseudo-random (but otherwise completely deterministic) mechanism for selecting the measurement settings, ...

  5. Products of Random Matrices from Polynomial Ensembles

    OpenAIRE

    Kieburg, Mario; Kösters, Holger

    2016-01-01

    Very recently we have shown that the spherical transform is a convenient tool for studying the relation between the joint density of the singular values and that of the eigenvalues for bi-unitarily invariant random matrices. In the present work we discuss the implications of these results for products of random matrices. In particular, we derive a transformation formula for the joint densities of a product of two independent bi-unitarily invariant random matrices, the first from a polynomial ...

  6. Randomization in substance abuse clinical trials

    OpenAIRE

    Woolson Robert F; Hedden Sarra L; Malcolm Robert J

    2006-01-01

    Abstract Background A well designed randomized clinical trial rates as the highest level of evidence for a particular intervention's efficacy. Randomization, a fundamental feature of clinical trials design, is a process invoking the use of probability to assign treatment interventions to patients. In general, randomization techniques pursue the goal of providing objectivity to the assignment of treatments, while at the same time balancing for treatment assignment totals and covariate distribu...

  7. Pseudo random signal processing theory and application

    CERN Document Server

    Zepernick, Hans-Jurgen

    2013-01-01

    In recent years, pseudo random signal processing has proven to be a critical enabler of modern communication, information, security and measurement systems. The signal's pseudo random, noise-like properties make it vitally important as a tool for protecting against interference, alleviating multipath propagation and allowing the potential of sharing bandwidth with other users. Taking a practical approach to the topic, this text provides a comprehensive and systematic guide to understanding and using pseudo random signals. Covering theoretical principles, design methodologies and applications

  8. True randomness from realistic quantum devices

    OpenAIRE

    Frauchiger, Daniela; Renner, Renato; Troyer, Matthias

    2013-01-01

    Even if the output of a Random Number Generator (RNG) is perfectly uniformly distributed, it may be correlated to pre-existing information and therefore be predictable. Statistical tests are thus not sufficient to guarantee that an RNG is usable for applications, e.g., in cryptography or gambling, where unpredictability is important. To enable such applications a stronger notion of randomness, termed "true randomness", is required, which includes independence from prior information. Quantum s...

  9. Assessing Cognitive Randomness: A Kolmogorov Complexity Approach

    CERN Document Server

    Gauvrit, Nicolas; Delahaye, Jean-Paul

    2011-01-01

    Since human randomness production has been studied and widely used to assess executive functions (especially inhibition), many measures have been suggested to assess the degree to which a sequence is random-like. However, each of them focuses on one feature of randomness, leading authors to have to use multiple measures. Here we describe and advocate for the use of the accepted universal measure for randomness based on algorithmic complexity, by means of a novel previously presented technique using the the definition of algorithmic probability. A re-analysis of the classical Radio Zenith data in the light of the proposed measure and methodology is provided as a study case of an application.

  10. A signal theoretic introduction to random processes

    CERN Document Server

    Howard, Roy M

    2015-01-01

    A fresh introduction to random processes utilizing signal theory By incorporating a signal theory basis, A Signal Theoretic Introduction to Random Processes presents a unique introduction to random processes with an emphasis on the important random phenomena encountered in the electronic and communications engineering field. The strong mathematical and signal theory basis provides clarity and precision in the statement of results. The book also features:  A coherent account of the mathematical fundamentals and signal theory that underpin the presented material Unique, in-depth coverage of

  11. Law of large numbers for non-elliptic random walks in dynamic random environments

    CERN Document Server

    Hollander, Frank den; Sidoravicius, Vladas

    2011-01-01

    We prove a law of large numbers for a class of $\\Z^d$-valued random walks in dynamic random environments, including \\emph{non-elliptic} examples. We assume that the random environment has a mixing property called \\emph{conditional cone-mixing} and that the random walk tends to stay inside space-time cones. The proof is based on a generalization of the regeneration scheme developed by Comets and Zeitouni for static random environments, which was adapted by Avena, den Hollander and Redig to dynamic random environments. We exhibit some one-dimensional examples to which our result applies. In some cases, the sign of the speed can be determined.

  12. Supersymmetry in random matrix theory

    International Nuclear Information System (INIS)

    I study the applications of supersymmetry in random matrix theory. I generalize the supersymmetry method and develop three new approaches to calculate eigenvalue correlation functions. These correlation functions are averages over ratios of characteristic polynomials. In the first part of this thesis, I derive a relation between integrals over anti-commuting variables (Grassmann variables) and differential operators with respect to commuting variables. With this relation I rederive Cauchy- like integral theorems. As a new application I trace the supermatrix Bessel function back to a product of two ordinary matrix Bessel functions. In the second part, I apply the generalized Hubbard-Stratonovich transformation to arbitrary rotation invariant ensembles of real symmetric and Hermitian self-dual matrices. This extends the approach for unitarily rotation invariant matrix ensembles. For the k-point correlation functions I derive supersymmetric integral expressions in a unifying way. I prove the equivalence between the generalized Hubbard-Stratonovich transformation and the superbosonization formula. Moreover, I develop an alternative mapping from ordinary space to superspace. After comparing the results of this approach with the other two supersymmetry methods, I obtain explicit functional expressions for the probability densities in superspace. If the probability density of the matrix ensemble factorizes, then the generating functions exhibit determinantal and Pfaffian structures. For some matrix ensembles this was already shown with help of other approaches. I show that these structures appear by a purely algebraic manipulation. In this new approach I use structures naturally appearing in superspace. I derive determinantal and Pfaffian structures for three types of integrals without actually mapping onto superspace. These three types of integrals are quite general and, thus, they are applicable to a broad class of matrix ensembles. (orig.)

  13. Supersymmetry in random matrix theory

    Energy Technology Data Exchange (ETDEWEB)

    Kieburg, Mario

    2010-05-04

    I study the applications of supersymmetry in random matrix theory. I generalize the supersymmetry method and develop three new approaches to calculate eigenvalue correlation functions. These correlation functions are averages over ratios of characteristic polynomials. In the first part of this thesis, I derive a relation between integrals over anti-commuting variables (Grassmann variables) and differential operators with respect to commuting variables. With this relation I rederive Cauchy- like integral theorems. As a new application I trace the supermatrix Bessel function back to a product of two ordinary matrix Bessel functions. In the second part, I apply the generalized Hubbard-Stratonovich transformation to arbitrary rotation invariant ensembles of real symmetric and Hermitian self-dual matrices. This extends the approach for unitarily rotation invariant matrix ensembles. For the k-point correlation functions I derive supersymmetric integral expressions in a unifying way. I prove the equivalence between the generalized Hubbard-Stratonovich transformation and the superbosonization formula. Moreover, I develop an alternative mapping from ordinary space to superspace. After comparing the results of this approach with the other two supersymmetry methods, I obtain explicit functional expressions for the probability densities in superspace. If the probability density of the matrix ensemble factorizes, then the generating functions exhibit determinantal and Pfaffian structures. For some matrix ensembles this was already shown with help of other approaches. I show that these structures appear by a purely algebraic manipulation. In this new approach I use structures naturally appearing in superspace. I derive determinantal and Pfaffian structures for three types of integrals without actually mapping onto superspace. These three types of integrals are quite general and, thus, they are applicable to a broad class of matrix ensembles. (orig.)

  14. Duration of luteal support (DOLS with progesterone pessaries to improve the success rates in assisted conception: study protocol for a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Gazvani Rafet

    2012-07-01

    Full Text Available Abstract Background Luteal support with progesterone is necessary for successful implantation of the embryo following egg collection and embryo transfer in an in-vitro fertilization (IVF cycle. Progesterone has been used for as little as 2 weeks and for as long as 12 weeks of gestation. The optimal length of treatment is unresolved at present and it remains unclear how long to treat women receiving luteal supplementation. Design The trial is a prospective, randomized, double-blind, placebo-controlled trial to investigate the effect of the duration of luteal support with progesterone in IVF cycles. Following 2 weeks standard treatment and a positive biochemical pregnancy test, this randomized control trial will allocate women to a supplementary 8 weeks treatment with vaginal progesterone or 8 weeks placebo. Further studies would be required to investigate whether additional supplementation with progesterone is beneficial in early pregnancy. Discussion Currently at the Hewitt Centre, approximately 32.5% of women have a positive biochemical pregnancy test 2 weeks after embryo transfer. It is this population that is eligible for trial entry and randomization. Once the patient has confirmed a positive urinary pregnancy test they will be invited to join the trial. Once the consent form has been completed by the patient a trial prescription sheet will be sent to pharmacy with a stated collection time. The patient can then be randomized and the drugs dispensed according to pharmacy protocol. A blood sample will then be drawn for measurement of baseline hormone levels (progesterone, estradiol, free beta-human chorionic gonadotrophin, pregnancy-associated plasma protein-A, Activin A, Inhibin A and Inhibin B. The primary outcome measure is the proportion of all randomized women that continue successfully to a viable pregnancy (at least one fetus with fetal heart rate >100 beats/minute on transabdominal/transvaginal ultrasound at 10 weeks post embryo

  15. A Mixed Flavonoid-Fish Oil Supplement Induces Immune-Enhancing and Anti-Inflammatory Transcriptomic Changes in Adult Obese and Overweight Women—A Randomized Controlled Trial

    Science.gov (United States)

    Cialdella-Kam, Lynn; Nieman, David C.; Knab, Amy M.; Shanely, R. Andrew; Meaney, Mary Pat; Jin, Fuxia; Sha, Wei; Ghosh, Sujoy

    2016-01-01

    Flavonoids and fish oils have anti-inflammatory and immune-modulating influences. The purpose of this study was to determine if a mixed flavonoid-fish oil supplement (Q-Mix; 1000 mg quercetin, 400 mg isoquercetin, 120 mg epigallocatechin (EGCG) from green tea extract, 400 mg n3-PUFAs (omega-3 polyunsaturated fatty acid) (220 mg eicosapentaenoic acid (EPA) and 180 mg docosahexaenoic acid (DHA)) from fish oil, 1000 mg vitamin C, 40 mg niacinamide, and 800 µg folic acid) would reduce complications associated with obesity; that is, reduce inflammatory and oxidative stress markers and alter genomic profiles in overweight women. Overweight and obese women (n = 48; age = 40–70 years) were assigned to Q-Mix or placebo groups using randomized double-blinded placebo-controlled procedures. Overnight fasted blood samples were collected at 0 and 10 weeks and analyzed for cytokines, C-reactive protein (CRP), F2-isoprostanes, and whole-blood-derived mRNA, which was assessed using Affymetrix HuGene-1_1 ST arrays. Statistical analysis included two-way ANOVA models for blood analytes and gene expression and pathway and network enrichment methods for gene expression. Plasma levels increased with Q-Mix supplementation by 388% for quercetin, 95% for EPA, 18% for DHA, and 20% for docosapentaenoic acid (DPA). Q-Mix did not alter plasma levels for CRP (p = 0.268), F2-isoprostanes (p = 0.273), and cytokines (p > 0.05). Gene set enrichment analysis revealed upregulation of pathways in Q-Mix vs. placebo related to interferon-induced antiviral mechanism (false discovery rate, FDR < 0.001). Overrepresentation analysis further disclosed an inhibition of phagocytosis-related inflammatory pathways in Q-Mix vs. placebo. Thus, a 10-week Q-Mix supplementation elicited a significant rise in plasma quercetin, EPA, DHA, and DPA, as well as stimulated an antiviral and inflammation whole-blood transcriptomic response in overweight women. PMID:27187447

  16. A Mixed Flavonoid-Fish Oil Supplement Induces Immune-Enhancing and Anti-Inflammatory Transcriptomic Changes in Adult Obese and Overweight Women—A Randomized Controlled Trial

    Directory of Open Access Journals (Sweden)

    Lynn Cialdella-Kam

    2016-05-01

    Full Text Available Flavonoids and fish oils have anti-inflammatory and immune-modulating influences. The purpose of this study was to determine if a mixed flavonoid-fish oil supplement (Q-Mix; 1000 mg quercetin, 400 mg isoquercetin, 120 mg epigallocatechin (EGCG from green tea extract, 400 mg n3-PUFAs (omega-3 polyunsaturated fatty acid (220 mg eicosapentaenoic acid (EPA and 180 mg docosahexaenoic acid (DHA from fish oil, 1000 mg vitamin C, 40 mg niacinamide, and 800 µg folic acid would reduce complications associated with obesity; that is, reduce inflammatory and oxidative stress markers and alter genomic profiles in overweight women. Overweight and obese women (n = 48; age = 40–70 years were assigned to Q-Mix or placebo groups using randomized double-blinded placebo-controlled procedures. Overnight fasted blood samples were collected at 0 and 10 weeks and analyzed for cytokines, C-reactive protein (CRP, F2-isoprostanes, and whole-blood-derived mRNA, which was assessed using Affymetrix HuGene-1_1 ST arrays. Statistical analysis included two-way ANOVA models for blood analytes and gene expression and pathway and network enrichment methods for gene expression. Plasma levels increased with Q-Mix supplementation by 388% for quercetin, 95% for EPA, 18% for DHA, and 20% for docosapentaenoic acid (DPA. Q-Mix did not alter plasma levels for CRP (p = 0.268, F2-isoprostanes (p = 0.273, and cytokines (p > 0.05. Gene set enrichment analysis revealed upregulation of pathways in Q-Mix vs. placebo related to interferon-induced antiviral mechanism (false discovery rate, FDR < 0.001. Overrepresentation analysis further disclosed an inhibition of phagocytosis-related inflammatory pathways in Q-Mix vs. placebo. Thus, a 10-week Q-Mix supplementation elicited a significant rise in plasma quercetin, EPA, DHA, and DPA, as well as stimulated an antiviral and inflammation whole-blood transcriptomic response in overweight women.

  17. A Mixed Flavonoid-Fish Oil Supplement Induces Immune-Enhancing and Anti-Inflammatory Transcriptomic Changes in Adult Obese and Overweight Women-A Randomized Controlled Trial.

    Science.gov (United States)

    Cialdella-Kam, Lynn; Nieman, David C; Knab, Amy M; Shanely, R Andrew; Meaney, Mary Pat; Jin, Fuxia; Sha, Wei; Ghosh, Sujoy

    2016-01-01

    Flavonoids and fish oils have anti-inflammatory and immune-modulating influences. The purpose of this study was to determine if a mixed flavonoid-fish oil supplement (Q-Mix; 1000 mg quercetin, 400 mg isoquercetin, 120 mg epigallocatechin (EGCG) from green tea extract, 400 mg n3-PUFAs (omega-3 polyunsaturated fatty acid) (220 mg eicosapentaenoic acid (EPA) and 180 mg docosahexaenoic acid (DHA)) from fish oil, 1000 mg vitamin C, 40 mg niacinamide, and 800 µg folic acid) would reduce complications associated with obesity; that is, reduce inflammatory and oxidative stress markers and alter genomic profiles in overweight women. Overweight and obese women (n = 48; age = 40-70 years) were assigned to Q-Mix or placebo groups using randomized double-blinded placebo-controlled procedures. Overnight fasted blood samples were collected at 0 and 10 weeks and analyzed for cytokines, C-reactive protein (CRP), F₂-isoprostanes, and whole-blood-derived mRNA, which was assessed using Affymetrix HuGene-1_1 ST arrays. Statistical analysis included two-way ANOVA models for blood analytes and gene expression and pathway and network enrichment methods for gene expression. Plasma levels increased with Q-Mix supplementation by 388% for quercetin, 95% for EPA, 18% for DHA, and 20% for docosapentaenoic acid (DPA). Q-Mix did not alter plasma levels for CRP (p = 0.268), F2-isoprostanes (p = 0.273), and cytokines (p > 0.05). Gene set enrichment analysis revealed upregulation of pathways in Q-Mix vs. placebo related to interferon-induced antiviral mechanism (false discovery rate, FDR < 0.001). Overrepresentation analysis further disclosed an inhibition of phagocytosis-related inflammatory pathways in Q-Mix vs. placebo. Thus, a 10-week Q-Mix supplementation elicited a significant rise in plasma quercetin, EPA, DHA, and DPA, as well as stimulated an antiviral and inflammation whole-blood transcriptomic response in overweight women. PMID:27187447

  18. The Impact of a Low Glycemic Index Diet on Inflammatory Markers and Serum Adiponectin Concentration in Adolescent Overweight and Obese Girls: A Randomized Clinical Trial.

    Science.gov (United States)

    Rouhani, M H; Kelishadi, R; Hashemipour, M; Esmaillzadeh, A; Surkan, P J; Keshavarz, A; Azadbakht, L

    2016-04-01

    Although the effects of dietary glycemic index (GI) on insulin resistance are well documented in adults, the complex interaction among glucose intolerance, inflammatory markers, and adipokine concentration has not been well studied, especially among adolescents. We investigated the effect of a low glycemic index (LGI) diet on insulin concentration, fasting blood sugar (FBS), inflammatory markers, and serum adiponectin concentration among healthy obese/overweight adolescent females. In this parallel randomized clinical trial, 2 different diets, an LGI diet and a healthy nutritional recommendation diet (HNRD) with similar macronutrient composition were prescribed to 50 obese and overweight adolescent girls with the same pubertal status. Biochemical markers FBS, serum insulin concentration, high sensitivity C-reactive protein (hs-CRP), interleukin 6 (IL-6), and adiponectin were measured before and after a 10 week intervention. Using an intention-to-treat analysis, data from 50 subjects were analyzed. According to a dietary assessment, GI in the LGI group was 43.22±0.54. While the mean for FBS, serum insulin concentration, the homeostasis model assessment (HOMA), the quantitative insulin sensitivity check index (QUICKI), and adiponectin concentration did not differ significantly within each group, the average hs-CRP and IL-6 decreased significantly in the LGI diet group after the 10 week intervention (p=0.009 and p=0.001; respectively). Comparing percent changes, we found a marginally significant decrease in hs-CRP in the LGI group compared with the HNRD group after adjusting for confounders. Compliance with an LGI diet may have favorable effect on inflammation among overweight and obese adolescent girls. PMID:27065462

  19. THE ANALYTICAL PROPERTIES FOR HOMOGENEOUS RANDOM TRANSITION FUNCTIONS

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The concepts of Markov process in random environment and homogeneous random transition functions are introduced. The necessary and sufficient conditions for homogeneous random transition function are given. The main results in this article are the analytical properties, such as continuity, differentiability, random Kolmogorov backward equation and random Kolmogorov forward equation of homogeneous random transition functions.

  20. The Equivalence Forms of Random Kolmogorov Forward (Backward) Equations

    Institute of Scientific and Technical Information of China (English)

    HU Di-he; HU Xiao-yu

    2005-01-01

    The concepts of Markov process in random environment, q-matrix in random environment and q-process in random environment are introduced. Three forms of random Kolmoogrov farward (or backward) equations are introduced and the equivalence of these three forms are also proved. Moreover any conservative q-process in random environment satisfies random Kolmogrov backward equation.

  1. Branching structure for an (L-1) random walk in random environment and its applications

    CERN Document Server

    Hong, Wenming

    2010-01-01

    By decomposing the random walk path, we construct a multitype branching process with immigration in random environment for corresponding random walk with bounded jumps in random environment. Then we give two applications of the branching structure. Firstly, we specify the explicit invariant density by a method different with the one used in Br\\'emont [3] and reprove the law of large numbers of the random walk by a method known as the environment viewed from particles". Secondly, the branching structure enables us to prove a stable limit law, generalizing the result of Kesten-Kozlov-Spitzer [11] for the nearest random walk in random environment. As a byproduct, we also prove that the total population of a multitype branching process in random environment with immigration before the first regeneration belongs to the domain of attraction of some \\kappa -stable law.

  2. A random version of Schaefer's fixed point theorem with applications to functional random integral equations

    Directory of Open Access Journals (Sweden)

    B. C. Dhage

    2004-09-01

    Full Text Available In this paper a random version of a fixed-point theorem of Schaefer is obtained and it is further applied to a certain nonlinear functional random integral equation for proving the existence result under Caratheodory conditions.

  3. Random energy model at complex temperatures

    Science.gov (United States)

    Saakian

    2000-06-01

    The complete phase diagram of the random energy model is obtained for complex temperatures using the method proposed by Derrida. We find the density of zeroes for the statistical sum. Then the method is applied to the generalized random energy model. This allowed us to propose an analytical method for investigating zeroes of the statistical sum for finite-dimensional systems. PMID:11088286

  4. Random shortest path metrics with applications

    NARCIS (Netherlands)

    Engels, Christian; Manthey, Bodo; Raghavendra Rao, B.V.; Brieden, A.; Görgülü, Z.-K.; Krug, T.; Kropat, E.; Meyer-Nieberg, S.; Mihelcic, G.; Pickl, S.W.

    2012-01-01

    We consider random metric instances for optimization problems obtained as follows: Every edge of a complete graph gets a weight drawn independently at random. And then the length of an edge is the length of a shortest path with respect to these weights that connects its two endpoints. We prove that

  5. DIMENSIONS FOR RANDOM SELF-CONFORMAL SETS

    Institute of Scientific and Technical Information of China (English)

    Liu Yanyan; Wu Jun

    2003-01-01

    A set is called regular if its Hausdorff dimension and upper box-counting dimension coincide.In this paper,we prove that the random self-conformal set is regular almost surely.Also we determine the dimensions for a class of random self-conformal sets.

  6. Motzkin numbers out of Random Domino Automaton

    CERN Document Server

    Białecki, Mariusz

    2011-01-01

    Motzkin numbers are derived from a special case of Random Domino Automaton - recently proposed toy model of earthquakes. An exact solution of the set of equations describing stationary state of Random Domino Automaton in "inverse-power" case is presented. A link with Motzkin numbers allows to present explicit form of asymptotic behaviour of the automaton.

  7. Critical Properties of Pure and Random Antiferromagnets

    DEFF Research Database (Denmark)

    Cowley, R. A.; Carneiro, K.

    1980-01-01

    Neutron scattering techniques have been used to study the critical properties of CoF2 and the randomly mixed systems: Co/ZnF2 and KMn/NiF3. The results for CoF2 are in excellent accord with the critical properties of the three-dimensional Ising model. In all of the random crystals studied the tra...

  8. Random vibration of mechanical and structural systems

    Science.gov (United States)

    Soong, T. T.; Grigoriu, Mircea

    This book addresses random vibration of mechanical and structural systems commonly encountered in aerospace, mechanical, and civil engineering. Techniques are examined for determining probabilistic characteristics of the response of dynamic systems subjected to random loads or inputs and for calculating probabilities related to system performance or reliability. Emphasis is given to applications.

  9. Color Charts, Esthetics, and Subjective Randomness

    Science.gov (United States)

    Sanderson, Yasmine B.

    2012-01-01

    Color charts, or grids of evenly spaced multicolored dots or squares, appear in the work of modern artists and designers. Often the artist/designer distributes the many colors in a way that could be described as "random," that is, without an obvious pattern. We conduct a statistical analysis of 125 "random-looking" art and design color charts and…

  10. Characterization of chaos in random maps

    CERN Document Server

    Loreto, V; Pasquini, M; Vulpiani, A

    1995-01-01

    We discuss the characterization of chaotic behaviours in random maps both in terms of the Lyapunov exponent and of the spectral properties of the Perron-Frobenius operator. In particular, we study a logistic map where the control parameter is extracted at random at each time step by considering finite dimensional approximation of the Perron-Frobenius operator

  11. Composed ensembles of random unitary ensembles

    CERN Document Server

    Pozniak, M; Kus, M; Pozniak, Marcin; Zyczkowski, Karol; Kus, Marek

    1997-01-01

    Composed ensembles of random unitary matrices are defined via products of matrices, each pertaining to a given canonical circular ensemble of Dyson. We investigate statistical properties of spectra of some composed ensembles and demonstrate their physical relevance. We discuss also the methods of generating random matrices distributed according to invariant Haar measure on the orthogonal and unitary group.

  12. Tensor Products of Random Unitary Matrices

    CERN Document Server

    Tkocz, Tomasz; Kus, Marek; Zeitouni, Ofer; Zyczkowski, Karol

    2012-01-01

    Tensor products of M random unitary matrices of size N from the circular unitary ensemble are investigated. We show that the spectral statistics of the tensor product of random matrices becomes Poissonian if M=2, N become large or M become large and N=2.

  13. The Design of Cluster Randomized Crossover Trials

    Science.gov (United States)

    Rietbergen, Charlotte; Moerbeek, Mirjam

    2011-01-01

    The inefficiency induced by between-cluster variation in cluster randomized (CR) trials can be reduced by implementing a crossover (CO) design. In a simple CO trial, each subject receives each treatment in random order. A powerful characteristic of this design is that each subject serves as its own control. In a CR CO trial, clusters of subjects…

  14. The design of cluster randomized crossover trials

    NARCIS (Netherlands)

    Rietbergen, C.; Moerbeek, M.

    2011-01-01

    The inefficiency induced by between-cluster variation in cluster randomized (CR) trials can be reduced by implementing a crossover (CO) design. In a simple CO trial, each subject receives each treatment in random order. A powerful characteristic of this design is that each subject serves as its own

  15. Perfectly Secure Oblivious RAM without Random Oracles

    DEFF Research Database (Denmark)

    Damgård, Ivan Bjerre; Meldgaard, Sigurd Torkel; Nielsen, Jesper Buus

    2011-01-01

    We present an algorithm for implementing a secure oblivious RAM where the access pattern is perfectly hidden in the information theoretic sense, without assuming that the CPU has access to a random oracle. In addition we prove a lower bound on the amount of randomness needed for implementing...... an information theoretically secure oblivious RAM....

  16. Concentration inequalities for random fields via coupling

    NARCIS (Netherlands)

    Chazottes, J. R.; Collet, P.; Kuelske, C.; Redig, F.

    2007-01-01

    We present a new and simple approach to concentration inequalities in the context of dependent random processes and random fields. Our method is based on coupling and does not use information inequalities. In case one has a uniform control on the coupling, one obtains exponential concentration inequ

  17. DEFICIENT FUNCTIONS OF RANDOM DIRICHLET SERIES

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    In this article, the uniqueness theorem of Dirichlet series is proved. Then the random Dirichlet series in the right half plane is studied, and the result that the random Dirichlet series of finite order has almost surely(a.s.) no deficient functions is proved.

  18. Transition matrix from a random walk

    CERN Document Server

    Schulman, Lawrence S

    2016-01-01

    Given a random walk a method is presented to produce a matrix of transition probabilities that is consistent with that random walk. The method is tested by using a transition matrix to produce a path and then using that path to create the estimate. The two matrices are then compared.

  19. Random queues and risk averse users

    DEFF Research Database (Denmark)

    de Palma, André; Fosgerau, Mogens

    2013-01-01

    We analyze Nash equilibrium in time of use of a congested facility. Users are risk averse with general concave utility. Queues are subject to varying degrees of random sorting, ranging from strict queue priority to a completely random queue. We define the key “no residual queue” property, which...

  20. Infinite Random Graphs as Statistical Mechanical Models

    DEFF Research Database (Denmark)

    Durhuus, Bergfinnur Jøgvan; Napolitano, George Maria

    2011-01-01

    We discuss two examples of infinite random graphs obtained as limits of finite statistical mechanical systems: a model of two-dimensional dis-cretized quantum gravity defined in terms of causal triangulated surfaces, and the Ising model on generic random trees. For the former model we describe...

  1. Fuzziness and randomness in an optimization framework

    International Nuclear Information System (INIS)

    This paper presents a semi-infinite approach for linear programming in the presence of fuzzy random variable coefficients. As a byproduct a way for dealing with optimization problems including both fuzzy and random data is obtained. Numerical examples are provided for the sake of illustration. (author). 13 refs

  2. Consequences of Violating Randomization in Cluster Sampling

    OpenAIRE

    Parrott Jason; Sawilowsky Shlomo

    2014-01-01

    Although not as efficient as simple random sampling, cluster sampling has been regarded as a valid sampling technique when the researcher is attempting to save cost. In order to do so, it is necessary that random selection occurs in all stages of sampling. This simulation study examines purposeful selection of cluster sampling in the second stage of a two stage cluster design.

  3. Sustained-Release Methylphenidate in a Randomized Trial of Treatment of Methamphetamine Use Disorder

    Science.gov (United States)

    Ling, Walter; Chang, Linda; Hillhouse, Maureen; Ang, Alfonso; Striebel, Joan; Jenkins, Jessica; Hernandez, Jasmin; Olaer, Mary; Mooney, Larissa; Reed, Susan; Fukaya, Erin; Kogachi, Shannon; Alicata, Daniel; Holmes, Nataliya; Esagoff, Asher

    2014-01-01

    Background and aims No effective pharmacotherapy for methamphetamine (MA) use disorder has yet been found. This study evaluated sustained-release methylphenidate (MPH-SR) compared with placebo (PLA) for treatment of MA use disorder in people also undergoing behavioural support and motivational incentives. Design This was a randomized, double-blind, placebo-controlled design with MPH-SR or PLA provided for 10 weeks (active phase) followed by 4 weeks of single-blind PLA. Twice-weekly clinic visits, weekly group counseling (CBT), and motivational incentives (MI) for MA-negative urine drug screens (UDS) were included. Setting Treatment sites were in Los Angeles, California (LA) and Honolulu, Hawaii (HH), USA. Participants 110 MA-dependent (via DSM-IV) participants (LA = 90; HH = 20). Measurements The primary outcome measure is self-reported days of MA use during the last 30 days of the active phase. Included in the current analyses are drug use (UDS and self-report), retention, craving, compliance (dosing, CBT, MI), adverse events, and treatment satisfaction. Findings No difference was found between treatment groups in self-reported days of MA use during the last 30 days of the active phase (p=0.22). In planned secondary outcomes analyses, however, the MPH group had fewer self-reported MA use days from baseline through the active phase compared with the PLA group (p=0.05). The MPH group also had lower craving scores and fewer marijuana-positive UDS than the PLA group in the last 30 days of the active phase. The two groups had similar retention, other drug use, adverse events, and treatment satisfaction. Conclusions Methylphenidate may lead to a reduction in concurrent methamphetamine use when provided as treatment for patients undergoing behavioural support for moderate to severe methamphetamine use disorder but this requires confirmation. PMID:24825486

  4. Alternating Current Stimulation for Vision Restoration after Optic Nerve Damage: A Randomized Clinical Trial

    Science.gov (United States)

    Schittkowski, Michael P.; Antal, Andrea; Ambrus, Géza Gergely; Paulus, Walter; Dannhauer, Moritz; Michalik, Romualda; Mante, Alf; Bola, Michal; Lux, Anke; Kropf, Siegfried; Brandt, Stephan A.; Sabel, Bernhard A.

    2016-01-01

    Background Vision loss after optic neuropathy is considered irreversible. Here, repetitive transorbital alternating current stimulation (rtACS) was applied in partially blind patients with the goal of activating their residual vision. Methods We conducted a multicenter, prospective, randomized, double-blind, sham-controlled trial in an ambulatory setting with daily application of rtACS (n = 45) or sham-stimulation (n = 37) for 50 min for a duration of 10 week days. A volunteer sample of patients with optic nerve damage (mean age 59.1 yrs) was recruited. The primary outcome measure for efficacy was super-threshold visual fields with 48 hrs after the last treatment day and at 2-months follow-up. Secondary outcome measures were near-threshold visual fields, reaction time, visual acuity, and resting-state EEGs to assess changes in brain physiology. Results The rtACS-treated group had a mean improvement in visual field of 24.0% which was significantly greater than after sham-stimulation (2.5%). This improvement persisted for at least 2 months in terms of both within- and between-group comparisons. Secondary analyses revealed improvements of near-threshold visual fields in the central 5° and increased thresholds in static perimetry after rtACS and improved reaction times, but visual acuity did not change compared to shams. Visual field improvement induced by rtACS was associated with EEG power-spectra and coherence alterations in visual cortical networks which are interpreted as signs of neuromodulation. Current flow simulation indicates current in the frontal cortex, eye, and optic nerve and in the subcortical but not in the cortical regions. Conclusion rtACS treatment is a safe and effective means to partially restore vision after optic nerve damage probably by modulating brain plasticity. This class 1 evidence suggests that visual fields can be improved in a clinically meaningful way. Trial Registration ClinicalTrials.gov NCT01280877 PMID:27355577

  5. A randomized controlled trial of atomoxetine in generalized social anxiety disorder.

    Science.gov (United States)

    Ravindran, Lakshmi N; Kim, Daniel S; Letamendi, Andrea M; Stein, Murray B

    2009-12-01

    The current mainstays of social anxiety disorder pharmacotherapy are serotonergic agents, with less known about the efficacy of more noradrenergic drugs. Atomoxetine (ATM), a highly selective norepinephrine reuptake inhibitor, is currently approved for the treatment of attention-deficit/hyperactivity disorder (ADHD). We describe the first controlled trial of ATM with respect to efficacy and tolerability in adults with the generalized subtype of social anxiety disorder (GSAD) without comorbid ADHD. Twenty-seven outpatients with clinically prevailing diagnoses of GSAD by the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition were randomized in a 1:1 ratio to 10 weeks of double-blind flexible-dose treatment with either ATM 40-100 mg per day (n = 14) or placebo (n = 13). Primary efficacy outcome was score at end point on the Liebowitz Social Anxiety Scale in the intention-to-treat sample. There were no significant group differences in patients completing the study (ATM, 79%; placebo, 77%). Whereas ATM was well tolerated, there were no significant differences in clinical efficacy between ATM and placebo for GSAD. There were few responders overall (ATM, 21%; placebo, 33%), but proportions were similar in each group (chi [1, 26] = 0.47; P = 0.67). Analysis of variance with repeated measures on the Liebowitz Social Anxiety Scale was performed to detect any differential change in social anxiety symptoms between groups. A significant time effect was found (F = 8.71; P = 0.007), but the time-by-treatment interaction was nonsignificant (F = 0.013; P = 0.91). Although the small sample size limits confidence in the reported results, the comparable, and low, response rates for ATM and placebo suggest that in the absence of comorbid ADHD, ATM is unlikely to be an effective agent for the treatment of GSAD. PMID:19910721

  6. Randomization in substance abuse clinical trials

    Directory of Open Access Journals (Sweden)

    Woolson Robert F

    2006-02-01

    Full Text Available Abstract Background A well designed randomized clinical trial rates as the highest level of evidence for a particular intervention's efficacy. Randomization, a fundamental feature of clinical trials design, is a process invoking the use of probability to assign treatment interventions to patients. In general, randomization techniques pursue the goal of providing objectivity to the assignment of treatments, while at the same time balancing for treatment assignment totals and covariate distributions. Numerous randomization techniques, each with varying properties of randomness and balance, are suggested in the statistical literature. This paper reviews common randomization techniques often used in substance abuse research and an application from a National Institute on Drug Abuse (NIDA-funded clinical trial in substance abuse is used to illustrate several choices an investigator faces when designing a clinical trial. Results Comparisons and contrasts of randomization schemes are provided with respect to deterministic and balancing properties. Specifically, Monte Carlo simulation is used to explore the balancing nature of randomization techniques for moderately sized clinical trials. Results demonstrate large treatment imbalance for complete randomization with less imbalance for the urn or adaptive scheme. The urn and adaptive randomization methods display smaller treatment imbalance as demonstrated by the low variability of treatment allocation imbalance. For all randomization schemes, covariate imbalance between treatment arms was small with little variation between adaptive schemes, stratified schemes and unstratified schemes given that sample sizes were moderate to large. Conclusion We develop this paper with the goal of reminding substance abuse researchers of the broad array of randomization options available for clinical trial designs. There may be too quick a tendency for substance abuse researchers to implement the fashionable urn

  7. Perturbing transient Random Walk in a Random Environment with cookies of maximal strength

    CERN Document Server

    Bauernschubert, Elisabeth

    2011-01-01

    We consider a left-transient random walk in a random environment on Z that will be disturbed by cookies inducing a drift to the right of strength 1. The number of cookies per site is i.i.d. and independent of the environment. Criteria for recurrence and transience of the random walk are obtained. For this purpose we use subcritical branching processes in random environments with immigration and formulate criteria for recurrence and transience for these processes.

  8. OPTIMISED RANDOM MUTATIONS FOR EVOLUTIONARY ALGORITHMS

    Directory of Open Access Journals (Sweden)

    Sean McGerty

    2014-07-01

    Full Text Available To demonstrate our approaches we will use Sudoku puzzles, which are an excellent test bed for evolutionary algorithms. The puzzles are accessible enough for people to enjoy. However the more complex puzzles require thousands of iterations before an evolutionary algorithm finds a solution. If we were attempting to compare evolutionary algorithms we could count their iterations to solution as an indicator of relative efficiency. Evolutionary algorithms however include a process of random mutation for solution candidates. We will show that by improving the random mutation behaviours we were able to solve problems with minimal evolutionary optimisation. Experiments demonstrated the random mutation was at times more effective at solving the harder problems than the evolutionary algorithms. This implies that the quality of random mutation may have a significant impact on the performance of evolutionary algorithms with Sudoku puzzles. Additionally this random mutation may hold promise for reuse in hybrid evolutionary algorithm behaviours.

  9. Randomization in clinical trials: conclusions and recommendations.

    Science.gov (United States)

    Lachin, J M; Matts, J P; Wei, L J

    1988-12-01

    The statistical properties of simple (complete) randomization, permuted-block (or simply blocked) randomization, and the urn adaptive biased-coin randomization are summarized. These procedures are contrasted to covariate adaptive procedures such as minimization and to response adaptive procedures such as the play-the-winner rule. General recommendations are offered regarding the use of complete, permuted-block, or urn randomization. In a large double-masked trial, any of these procedures may be acceptable. For a given trial, the relative merits of each procedure should be carefully weighed in relation to the characteristics of the trial. Important considerations are the size of the trial, overall as well as within the smallest subgroup to be employed in a subgroup-specific analysis, whether or not the trial is to be masked, and the resources needed to perform the proper randomization-based permutational analysis. PMID:3203526

  10. Gaussian Networks Generated by Random Walks

    CERN Document Server

    Javarone, Marco Alberto

    2014-01-01

    We propose a random walks based model to generate complex networks. Many authors studied and developed different methods and tools to analyze complex networks by random walk processes. Just to cite a few, random walks have been adopted to perform community detection, exploration tasks and to study temporal networks. Moreover, they have been used also to generate scale-free networks. In this work, we define a random walker that plays the role of "edges-generator". In particular, the random walker generates new connections and uses these ones to visit each node of a network. As result, the proposed model allows to achieve networks provided with a Gaussian degree distribution, and moreover, some features as the clustering coefficient and the assortativity show a critical behavior. Finally, we performed numerical simulations to study the behavior and the properties of the cited model.

  11. Randomized transmit and receive ultrasound tomography

    CERN Document Server

    Clement, Gregory T

    2015-01-01

    A tomographic method is considered that forms images from sets of spatially randomized source signals and receiver sensitivities. The method is designed to allow image reconstruction for an extended number of transmitters and receivers in the presence noise and without plane wave approximation or otherwise approximation on the size or regularity of source and receiver functions. An overdetermined set of functions are formed from the Hadamard product between a Gaussian function and a uniformly distributed random number set. It is shown that this particular type of randomization tends to produce well-conditioned matrices whose pseudoinverses may be determined without implementing relaxation methods. When the inverted sets are applied to simulated first-order scattering from a Shepp-Logan phantom, successful image reconstructions are achieved for signal-to-noise ratios (SNR) as low as 1. Evaluation of the randomization approach is conducted by comparing condition numbers with other forms of signal randomization....

  12. Statistical mechanics of fuzzy random polymer networks

    Institute of Scientific and Technical Information of China (English)

    陈晓红

    1995-01-01

    A statistical mechanics framework of fuzzy random polymer networks is established based on the theories of fuzzy systems. The entanglement effect is manifested quantitatively by introducing an entanglement tensor and membership function and the amorphous structure is treated as the fuzzy random network made up of macromolecular coils entangled randomly. A random tetrahedral entangled-crosslinked cell is chosen as an average representative unit of the fuzzy random polymer network structure. By making use of the theory of fuzzy probability and statistical mechanics, the expression for the free energy of deformation is given, which fits well with the experimental data on rubber elasticity under various deformation modes. Both classical statistical theory and Mooney-Rivlin equation can be taken as its special cases.

  13. Bit recycling for scaling random number generators

    CERN Document Server

    Mennucci, Andrea C G

    2010-01-01

    Many Random Number Generators (RNG) are available nowadays; they are divided in two categories, hardware RNG, that provide "true" random numbers, and algorithmic RNG, that generate pseudo random numbers (PRNG). Both types usually generate random numbers (X_n) as independent uniform samples in a range 0...2^b-1, with b = 8, 16, 32 or b = 64. In applications, it is instead sometimes desirable to draw random numbers as independent uniform samples (Y_n) in a range 1, . . . M, where moreover M may change between drawings. Transforming the sequence (X_n) to (Y_n) is sometimes known as scaling. We discuss different methods for scaling the RNG, both in term of mathematical efficiency and of computational speed.

  14. Generation of Random Numbers by Micromechanism

    Science.gov (United States)

    Mita, Makoto; Toshiyoshi, Hiroshi; Ataka, Manabu; Fujita, Hiroyuki

    We have successfully developed a novel micromechanism of random number generator (RNG) by using the silicon micromachining technique. The MEM(Micro Electro Mechanical)RNG produce a series of random numbers by using the pull-in instability of electrostatic actuation operated with a typical dc 150 volt. The MEM RNG is made by the deep reactive ion etching of a silicon-on-insulator(SOI) wafer, and is very small compared with the conventional RNG hardware based on the randomness of thermal noise or isotope radiation. Quality of randomness has been experimentally confirmed by the self-correlation study of the generated series of numbers. The MEM RNG proposed here would be a true random number generation, which is needed for the highly secured encryption system of today’s information technology.

  15. Monocular Road Detection Using Structured Random Forest

    Directory of Open Access Journals (Sweden)

    Liang Xiao

    2016-05-01

    Full Text Available Road detection is a key task for autonomous land vehicles. Monocular vision-based road detection algorithms are mostly based on machine learning approaches and are usually cast as classification problems. However, the pixel-wise classifiers are faced with the ambiguity caused by changes in road appearance, illumination and weather. An effective way to reduce the ambiguity is to model the contextual information with structured learning and prediction. Currently, the widely used structured prediction model in road detection is the Markov random field or conditional random field. However, the random field-based methods require additional complex optimization after pixel-wise classification, making them unsuitable for real-time applications. In this paper, we present a structured random forest-based road-detection algorithm which is capable of modelling the contextual information efficiently. By mapping the structured label space to a discrete label space, the test function of each split node can be trained in a similar way to that of the classical random forests. Structured random forests make use of the contextual information of image patches as well as the structural information of the labels to get more consistent results. Besides this benefit, by predicting a batch of pixels in a single classification, the structured random forest-based road detection can be much more efficient than the conventional pixel-wise random forest. Experimental results tested on the KITTI-ROAD dataset and data collected in typical unstructured environments show that structured random forest-based road detection outperforms the classical pixel-wise random forest both in accuracy and efficiency.

  16. Estimating the Causal Effect of Randomization versus Treatment Preference in a Doubly Randomized Preference Trial

    Science.gov (United States)

    Marcus, Sue M.; Stuart, Elizabeth A.; Wang, Pei; Shadish, William R.; Steiner, Peter M.

    2012-01-01

    Although randomized studies have high internal validity, generalizability of the estimated causal effect from randomized clinical trials to real-world clinical or educational practice may be limited. We consider the implication of randomized assignment to treatment, as compared with choice of preferred treatment as it occurs in real-world…

  17. A Strong Limit Theorem on Generalized Random Selection for m-valued Random Sequences

    Institute of Scientific and Technical Information of China (English)

    WANGZhong-zhi; XUFu-xia

    2003-01-01

    In this paper, a strong limit theorem on gambling strategy for binary Bernoulli sequence, i.e.irregularity theorem, is extended to random selection for dependent m-valued random variables, via using a new method-differentiability on net. Furthermore, by allowing the selection function to take value in finite interval [-M, M], the conception of random selection is generalized.

  18. Effect of workplace- versus home-based physical exercise on pain in healthcare workers: study protocol for a single blinded cluster randomized controlled trial

    Science.gov (United States)

    2014-01-01

    (primary outcome) and physical exertion during work, social capital and work ability (secondary outcomes) is assessed at baseline and 10-week follow-up. Further, postural balance and mechanical muscle function is assessed during clinical examination at baseline and follow-up. Discussion This cluster randomized trial will investigate the change in self-rated average pain intensity in the back, neck and shoulder after either 10 weeks of physical exercise at the workplace or at home. Trial registration ClinicalTrials.gov (NCT01921764). PMID:24708570

  19. Evaluation of the efficacy and safety of olanzapine as an adjunctive treatment for anorexia nervosa in adolescent females: a randomized, double-blind, placebo-controlled trial

    Directory of Open Access Journals (Sweden)

    Moher David

    2008-01-01

    Full Text Available Abstract Background Anorexia Nervosa (AN is a serious, debilitating condition that causes significant physical, emotional, and functional impairment. The condition is characterized by destructive weight loss behaviours and a refusal to maintain body weight at or above a minimally normal weight for age and height. AN often develops in adolescence and is a predominantly female disorder. Treatment for AN typically involves medical, nutritional and psychological interventions. Pharmacotherapy is also often used; however, the literature on the effectiveness of these drugs in a pediatric population is very limited. Olanzapine, which is an 'atypical' antipsychotic, is becoming more widespread in the treatment of AN. Olanzapine is hypothesized to facilitate weight gain, while decreasing levels of agitation and decreasing resistance to treatment in young women with AN. This randomized, double-blind placebo-controlled trial seeks to examine the effectiveness and safety of olanzapine in female youth with AN. Methods/Design Adolescent females between the ages of 12 and 17 diagnosed with AN (either restricting or binge/purge type or Eating Disorder Not Otherwise Specified with a Body Mass Index of less than or equal to 17.5, will be offered inclusion in the study. Patients will be randomly assigned to receive either olanzapine or placebo. Patients assigned to receive olanzapine will start at a low dose of 1.25 mg/day for three days, followed by 2.5 mg/day for four days, 5 mg/day for one week, then 7.5 mg/day (the target dose chosen for 10 weeks. After 10 weeks at 7.5 mg the medication will be tapered and discontinued over a period of two weeks. The effectiveness of olanzapine versus placebo will be determined by investigating the change from baseline on measures of eating attitudes and behaviors, depression and anxiety, and change in Body Mass Index at week 12, and after a follow-up period at week 40. It is anticipated that 67 participants will be recruited

  20. Dynamic Output Feedback Control for Nonlinear Networked Control Systems with Random Packet Dropout and Random Delay

    Directory of Open Access Journals (Sweden)

    Shuiqing Yu

    2013-01-01

    Full Text Available This paper investigates the dynamic output feedback control for nonlinear networked control systems with both random packet dropout and random delay. Random packet dropout and random delay are modeled as two independent random variables. An observer-based dynamic output feedback controller is designed based upon the Lyapunov theory. The quantitative relationship of the dropout rate, transition probability matrix, and nonlinear level is derived by solving a set of linear matrix inequalities. Finally, an example is presented to illustrate the effectiveness of the proposed method.

  1. Private Randomness Expansion With Untrusted Devices

    CERN Document Server

    Colbeck, Roger

    2010-01-01

    Randomness is an important resource for many applications, from gambling to secure communication. However, guaranteeing that the output from a candidate random source could not have been predicted by an outside party is a challenging task, and many supposedly random sources used today provide no such guarantee. Quantum solutions to this problem exist, for example a device which internally sends a photon through a beam-splitter and observes on which side it emerges, but, presently, such solutions require the user to trust the internal workings of the device. Here we seek to go beyond this limitation by asking whether randomness can be generated using untrusted devices|even ones created by an adversarial agent|while providing a guarantee that no outside party (including the agent) can predict it. Since this is easily seen to be impossible unless the user has an initially private random string, the task we investigate here is private randomness expansion. We introduce a protocol for private randomness expansion ...

  2. Wave propagation in random granular chains.

    Science.gov (United States)

    Manjunath, Mohith; Awasthi, Amnaya P; Geubelle, Philippe H

    2012-03-01

    The influence of randomness on wave propagation in one-dimensional chains of spherical granular media is investigated. The interaction between the elastic spheres is modeled using the classical Hertzian contact law. Randomness is introduced in the discrete model using random distributions of particle mass, Young's modulus, or radius. Of particular interest in this study is the quantification of the attenuation in the amplitude of the impulse associated with various levels of randomness: two distinct regimes of decay are observed, characterized by an exponential or a power law, respectively. The responses are normalized to represent a vast array of material parameters and impact conditions. The virial theorem is applied to investigate the transfer from potential to kinetic energy components in the system for different levels of randomness. The level of attenuation in the two decay regimes is compared for the three different sources of randomness and it is found that randomness in radius leads to the maximum rate of decay in the exponential regime of wave propagation. PMID:22587093

  3. Wave propagation in random granular chains.

    Science.gov (United States)

    Manjunath, Mohith; Awasthi, Amnaya P; Geubelle, Philippe H

    2012-03-01

    The influence of randomness on wave propagation in one-dimensional chains of spherical granular media is investigated. The interaction between the elastic spheres is modeled using the classical Hertzian contact law. Randomness is introduced in the discrete model using random distributions of particle mass, Young's modulus, or radius. Of particular interest in this study is the quantification of the attenuation in the amplitude of the impulse associated with various levels of randomness: two distinct regimes of decay are observed, characterized by an exponential or a power law, respectively. The responses are normalized to represent a vast array of material parameters and impact conditions. The virial theorem is applied to investigate the transfer from potential to kinetic energy components in the system for different levels of randomness. The level of attenuation in the two decay regimes is compared for the three different sources of randomness and it is found that randomness in radius leads to the maximum rate of decay in the exponential regime of wave propagation.

  4. Low-noise Brillouin random fiber laser with a random grating-based resonator.

    Science.gov (United States)

    Xu, Yanping; Gao, Song; Lu, Ping; Mihailov, Stephen; Chen, Liang; Bao, Xiaoyi

    2016-07-15

    A novel Brillouin random fiber laser (BRFL) with the random grating-based Fabry-Perot (FP) resonator is proposed and demonstrated. Significantly enhanced random feedback from the femtosecond laser-fabricated random grating overwhelms the Rayleigh backscattering, which leads to efficient Brillouin gain for the lasing modes and reduced lasing threshold. Compared to the intensity and frequency noises of the Rayleigh feedback resonator, those of the proposed random laser are effectively suppressed due to the reduced resonating modes and mode competition resulting from the random grating-formed filters. Using the heterodyne technique, the linewidth of the coherent random lasing spike is measured to be ∼45.8  Hz. PMID:27420494

  5. Continuity and anomalous fluctuations in random walks in dynamic random environments: numerics, phase diagrams and conjectures

    CERN Document Server

    Avena, L

    2012-01-01

    We perform simulations for one dimensional continuous-time random walks in two dynamic random environments with fast (independent spin-flips) and slow (simple symmetric exclusion) decay of space-time correlations, respectively. We focus on the asymptotic speeds and the scaling limits of such random walks. We observe different behaviors depending on the dynamics of the underlying random environment and the ratio between the jump rate of the random walk and the one of the environment. We compare our data with well known results for static random environment. We observe that the non-diffusive regime known so far only for the static case can occur in the dynamic setup too. Such anomalous fluctuations emerge in a new phase diagram. Further we discuss possible consequences for general static and dynamic random environments.

  6. Random light beams theory and applications

    CERN Document Server

    Korotkova, Olga

    2013-01-01

    Random Light Beams: Theory and Applications contemplates the potential in harnessing random light. This book discusses light matter interactions, and concentrates on the various phenomena associated with beam-like fields. It explores natural and man-made light fields and gives an overview of recently introduced families of random light beams. It outlines mathematical tools for analysis, suggests schemes for realization, and discusses possible applications. The book introduces the essential concepts needed for a deeper understanding of the subject, discusses various classes of deterministic par

  7. Scaling of random walk betweenness in networks

    CERN Document Server

    Narayan, O

    2016-01-01

    The betweenness centrality of graphs using random walk paths instead of geodesics is studied. A scaling collapse with no adjustable parameters is obtained as the graph size $N$ is varied; the scaling curve depends on the graph model. A normalized random betweenness, that counts each walk passing through a node only once, is also defined. It is argued to be more useful and seen to have simpler scaling behavior. In particular, the probability for a random walk on a preferential attachment graph to pass through the root node is found to tend to unity as $N\\rightarrow\\infty.$

  8. Random torsional vibration in automobile transmissions

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    The action of a road profile to the torsional vibrations in automobile transmissions is studied. The model to calculate the random torsional vibrations in the transmissions is proposed and the values of the model parameters are determined by both computation and experiment. Furthermore, the dynamic characteristics and the responses of automobile transmissions to the random excitation of road profile are calculated. The results of road experiment demonstrate that the theoretic analyses and the calculation are correct, which imply that the low frequency torsional vibrations in automobile transmissions are caused by the random excitation of a road profile.

  9. Elements of random walk and diffusion processes

    CERN Document Server

    Ibe, Oliver C

    2013-01-01

    Presents an important and unique introduction to random walk theory Random walk is a stochastic process that has proven to be a useful model in understanding discrete-state discrete-time processes across a wide spectrum of scientific disciplines. Elements of Random Walk and Diffusion Processes provides an interdisciplinary approach by including numerous practical examples and exercises with real-world applications in operations research, economics, engineering, and physics. Featuring an introduction to powerful and general techniques that are used in the application of physical and dynamic

  10. Modelling complex networks by random hierarchical graphs

    Directory of Open Access Journals (Sweden)

    M.Wróbel

    2008-06-01

    Full Text Available Numerous complex networks contain special patterns, called network motifs. These are specific subgraphs, which occur oftener than in randomized networks of Erdős-Rényi type. We choose one of them, the triangle, and build a family of random hierarchical graphs, being Sierpiński gasket-based graphs with random "decorations". We calculate the important characteristics of these graphs - average degree, average shortest path length, small-world graph family characteristics. They depend on probability of decorations. We analyze the Ising model on our graphs and describe its critical properties using a renormalization-group technique.

  11. Statistical properties of random density matrices

    CERN Document Server

    Sommers, H J; Sommers, Hans-Juergen; Zyczkowski, Karol

    2004-01-01

    Statistical properties of ensembles of random density matrices are investigated. We compute traces and von Neumann entropies averaged over ensembles of random density matrices distributed according to the Bures measure. The eigenvalues of the random density matrices are analyzed: we derive the eigenvalue distribution for the Bures ensemble which is shown to be broader then the quarter--circle distribution characteristic of the Hilbert--Schmidt ensemble. For measures induced by partial tracing over the environment we compute exactly the two-point eigenvalue correlation function.

  12. Statistical properties of random density matrices

    Energy Technology Data Exchange (ETDEWEB)

    Sommers, Hans-Juergen [Fachbereich Physik, Universitaet Duisburg-Essen, Campus Essen, 45117 Essen (Germany); Zyczkowski, Karol [Instytut Fizyki im. Smoluchowskiego, Uniwersytet Jagiellonski, ul. Reymonta 4, 30-059 Cracow (Poland)

    2004-09-03

    Statistical properties of ensembles of random density matrices are investigated. We compute traces and von Neumann entropies averaged over ensembles of random density matrices distributed according to the Bures measure. The eigenvalues of the random density matrices are analysed: we derive the eigenvalue distribution for the Bures ensemble which is shown to be broader then the quarter-circle distribution characteristic of the Hilbert-Schmidt ensemble. For measures induced by partial tracing over the environment we compute exactly the two-point eigenvalue correlation function.

  13. Randomness as a resource for design

    DEFF Research Database (Denmark)

    Leong, T.; Vetere, F.; Howard, Steve

    2006-01-01

    examining the influence of randomness on the user experience of music listening. 113 instances of self-reporting were collected and analysed according to four themes: listening mode, content organisation, activities during listening, and affective outcomes. The analysis provides insights into how randomness...... is used to engender certain affective responses (such as feeling refreshed) by using various constraining techniques (such as playlists) whilst engaging in everyday activities (such as driving a car). The paper argues that randomness can be used as an innovative design resource for supporting rich...

  14. Supercritical branching diffusions in random environment

    CERN Document Server

    Hutzenthaler, Martin

    2011-01-01

    Supercritical branching processes in constant environment conditioned on eventual extinction are known to be subcritical branching processes. The case of random environment is more subtle. A supercritical branching diffusion in random environment (BDRE) conditioned on eventual extinction of the population is not a BDRE. However the quenched law of the population size of a supercritical BDRE conditioned on eventual extinction is equal to the quenched law of the population size of a subcritical BDRE. As a consequence, supercritical BDREs have a phase transition which is similar to a well-known phase transition of subcritical branching processes in random environment.

  15. A Random Walk to Economic Freedom?

    Directory of Open Access Journals (Sweden)

    Witte, Mark David

    2013-04-01

    Full Text Available Given the wide use of economic freedom in economic literature it is imperative to understand how economic freedom evolves. Results suggest that levels of economic freedom are dominated by random shocks. Using a test for stationarity devised by Westerlund and Larsson (2012 we are unable to reject the null hypothesis of a random walk. The changes to economic freedom also are mostly driven by random shocks with only a minor role played by country specific characteristics. Additionally, changes to economic freedom are partially reversed as increases (decreases in one year are partially offset by decreases (increases in the next year.

  16. A random matrix theory of decoherence

    Science.gov (United States)

    Gorin, T.; Pineda, C.; Kohler, H.; Seligman, T. H.

    2008-11-01

    Random matrix theory is used to represent generic loss of coherence of a fixed central system coupled to a quantum-chaotic environment, represented by a random matrix ensemble, via random interactions. We study the average density matrix arising from the ensemble induced, in contrast to previous studies where the average values of purity, concurrence and entropy were considered; we further discuss when one or the other approach is relevant. The two approaches agree in the limit of large environments. Analytic results for the average density matrix and its purity are presented in linear response approximation. The two-qubit system is analysed, mainly numerically, in more detail.

  17. A random matrix theory of decoherence

    Energy Technology Data Exchange (ETDEWEB)

    Gorin, T [Departamento de FIsica, Universidad de Guadalajara, Blvd Marcelino GarcIa Barragan y Calzada OlImpica, Guadalajara CP 44840, JalIsco (Mexico); Pineda, C [Institut fuer Physik und Astronomie, University of Potsdam, 14476 Potsdam (Germany); Kohler, H [Fachbereich Physik, Universitaet Duisburg-Essen, D-47057 Duisburg (Germany); Seligman, T H [Instituto de Ciencias FIsicas, Universidad Nacional Autonoma de Mexico (Mexico)], E-mail: thomas.gorin@red.cucei.udg.mx, E-mail: carlospgmat03@gmail.com

    2008-11-15

    Random matrix theory is used to represent generic loss of coherence of a fixed central system coupled to a quantum-chaotic environment, represented by a random matrix ensemble, via random interactions. We study the average density matrix arising from the ensemble induced, in contrast to previous studies where the average values of purity, concurrence and entropy were considered; we further discuss when one or the other approach is relevant. The two approaches agree in the limit of large environments. Analytic results for the average density matrix and its purity are presented in linear response approximation. The two-qubit system is analysed, mainly numerically, in more detail.

  18. Random nanolasing in the Anderson localized regime

    DEFF Research Database (Denmark)

    Liu, Jin; Garcia, P. D.; Ek, Sara;

    2014-01-01

    multiple scattering. The applicability of random lasers has been limited due to multidirectional emission, lack of tunability, and strong mode competition with chaotic fluctuations due to a weak mode confinement. The regime of Anderson localization of light has been proposed for obtaining stable multimode...... random lasing, and initial work concerned macroscopic one-dimensional layered media. Here, we demonstrate on-chip random nanolasers where the cavity feedback is provided by the intrinsic disorder. The strong confinement achieved by Anderson localization reduces the spatial overlap between lasing modes...

  19. Localization length fluctuation in randomly layered media

    Science.gov (United States)

    Yuan, Haiming; Huang, Feng; Jiang, Xiangqian; Sun, Xiudong

    2016-10-01

    Localization properties of the two-component randomly layered media (RLM) are studied in detail both analytically and numerically. The localization length is found fluctuating around the analytical result obtained under the high-frequency limit. The fluctuation amplitude approaches zero with the increasing of disorder, which is characterized by the distribution width of random thickness. It is also found that the localization length over the mean thickness periodically varies with the distribution center of random thickness. For the multi-component RLM structure, the arrangement of material must be considered.

  20. Optimal randomness generation from optical Bell experiments

    International Nuclear Information System (INIS)

    Genuine randomness can be certified from Bell tests without any detailed assumptions on the working of the devices with which the test is implemented. An important class of experiments for implementing such tests is optical setups based on polarization measurements of entangled photons distributed from a spontaneous parametric down conversion source. Here we compute the maximal amount of randomness which can be certified in such setups under realistic conditions. We provide relevant yet unexpected numerical values for the physical parameters and achieve four times more randomness than previous methods. (fast track communication)

  1. Mindfulness-Oriented Recovery Enhancement versus CBT for co-occurring substance dependence, traumatic stress, and psychiatric disorders: Proximal outcomes from a pragmatic randomized trial.

    Science.gov (United States)

    Garland, Eric L; Roberts-Lewis, Amelia; Tronnier, Christine D; Graves, Rebecca; Kelley, Karen

    2016-02-01

    In many clinical settings, there is a high comorbidity between substance use disorders, psychiatric disorders, and traumatic stress. Novel therapies are needed to address these co-occurring issues efficiently. The aim of the present study was to conduct a pragmatic randomized controlled trial comparing Mindfulness-Oriented Recovery Enhancement (MORE) to group Cognitive-Behavioral Therapy (CBT) and treatment-as-usual (TAU) for previously homeless men residing in a therapeutic community. Men with co-occurring substance use and psychiatric disorders, as well as extensive trauma histories, were randomly assigned to 10 weeks of group treatment with MORE (n = 64), CBT (n = 64), or TAU (n = 52). Study findings indicated that from pre-to post-treatment MORE was associated with modest yet significantly greater improvements in substance craving, post-traumatic stress, and negative affect than CBT, and greater improvements in post-traumatic stress and positive affect than TAU. A significant indirect effect of MORE on decreasing craving and post-traumatic stress by increasing dispositional mindfulness was observed, suggesting that MORE may target these issues via enhancing mindful awareness in everyday life. This pragmatic trial represents the first head-to-head comparison of MORE against an empirically-supported treatment for co-occurring disorders. Results suggest that MORE, as an integrative therapy designed to bolster self-regulatory capacity, may hold promise as a treatment for intersecting clinical conditions.

  2. Faster generation of random spanning trees

    CERN Document Server

    Kelner, Jonathan A

    2009-01-01

    In this paper, we set forth a new algorithm for generating approximately uniformly random spanning trees in undirected graphs. We show how to sample from a distribution that is within a multiplicative $(1+\\delta)$ of uniform in expected time $\\TO(m\\sqrt{n}\\log 1/\\delta)$. This improves the sparse graph case of the best previously known worst-case bound of $O(\\min \\{mn, n^{2.376}\\})$, which has stood for twenty years. To achieve this goal, we exploit the connection between random walks on graphs and electrical networks, and we use this to introduce a new approach to the problem that integrates discrete random walk-based techniques with continuous linear algebraic methods. We believe that our use of electrical networks and sparse linear system solvers in conjunction with random walks and combinatorial partitioning techniques is a useful paradigm that will find further applications in algorithmic graph theory.

  3. Quantum chaotic dynamics and random polynomials

    Energy Technology Data Exchange (ETDEWEB)

    Bogomolny, E.; Bohigas, O.; Leboeuf, P.

    1995-11-01

    The distribution of roots of polynomials of high degree with random coefficients is investigated which, among others, appear naturally in the context of `quantum chaotic dynamics`. It is shown that under quite general conditions their roots tend to concentrate near the unit circle in the complex plane. In order to further increase this tendency, the particular case of self-inverse random polynomials is studied, and it is shown that for them a finite portion of all roots lies exactly on the unit circle. Correlation functions of these roots are also computed analytically, and compared to the correlations of eigenvalues of random matrices. The problem of ergodicity of chaotic wavefunctions is also considered. Special attention is devoted to the role of symmetries in the distribution of roots of random polynomials. (author). 32 refs.

  4. Uniform dimension results for Gaussian random fields

    Institute of Scientific and Technical Information of China (English)

    WU DongSheng; XIAO YiMin

    2009-01-01

    Let X = {X(t), t ∈ RN} be a Gaussian random field with values in Rd defined by x(t) = (x1(t),…,xd(t)), At∈RN.(1)The properties of space and time anisotropy of X and their connections to uniform Hausdorff dimension results are discussed. It is shown that in general the uniform Hausdorff dimension result does not hold for the image sets of a space-anisotropic Gaussian random field X. When X is an (N, d)-Gaussian random field as in (1), where X1,..., Xd are independent copies of a real valued, centered Gaussian random field Xo which is anisotropic in the time variable. We establish uniform Hausdorff dimension results for the image sets of X. These results extend the corresponding results on one-dimensional Brownian motion, fractional Brownian motion and the Brownian sheet.

  5. Blinding in randomized clinical trials: imposed impartiality

    DEFF Research Database (Denmark)

    Hróbjartsson, A; Boutron, I

    2011-01-01

    Blinding, or "masking," is a crucial method for reducing bias in randomized clinical trials. In this paper, we review important methodological aspects of blinding, emphasizing terminology, reporting, bias mechanisms, empirical evidence, and the risk of unblinding. Theoretical considerations...

  6. Palm theory for random time changes

    Directory of Open Access Journals (Sweden)

    Masakiyo Miyazawa

    2001-01-01

    Full Text Available Palm distributions are basic tools when studying stationarity in the context of point processes, queueing systems, fluid queues or random measures. The framework varies with the random phenomenon of interest, but usually a one-dimensional group of measure-preserving shifts is the starting point. In the present paper, by alternatively using a framework involving random time changes (RTCs and a two-dimensional family of shifts, we are able to characterize all of the above systems in a single framework. Moreover, this leads to what we call the detailed Palm distribution (DPD which is stationary with respect to a certain group of shifts. The DPD has a very natural interpretation as the distribution seen at a randomly chosen position on the extended graph of the RTC, and satisfies a general duality criterion: the DPD of the DPD gives the underlying probability P in return.

  7. Generating Realistic Labelled, Weighted Random Graphs

    CERN Document Server

    Davis, Michael Charles; Liu, Weiru; Miller, Paul; Hunter, Ruth; Kee, Frank

    2015-01-01

    Generative algorithms for random graphs have yielded insights into the structure and evolution of real-world networks. Most networks exhibit a well-known set of properties, such as heavy-tailed degree distributions, clustering and community formation. Usually, random graph models consider only structural information, but many real-world networks also have labelled vertices and weighted edges. In this paper, we present a generative model for random graphs with discrete vertex labels and numeric edge weights. The weights are represented as a set of Beta Mixture Models (BMMs) with an arbitrary number of mixtures, which are learned from real-world networks. We propose a Bayesian Variational Inference (VI) approach, which yields an accurate estimation while keeping computation times tractable. We compare our approach to state-of-the-art random labelled graph generators and an earlier approach based on Gaussian Mixture Models (GMMs). Our results allow us to draw conclusions about the contribution of vertex labels a...

  8. Asymptotic Theory of Cepstral Random Fields

    CERN Document Server

    McElroy, Tucker S

    2011-01-01

    Random fields play a central role in the analysis of spatially correlated data and, as a result, have a significant impact on a broad array of scientific applications. Given the importance of this topic, there has been substantial research devoted to this area. However, in spite of the tremendous research to date, outside the engineering literature, the cepstral random field model remains largely underdeveloped. We provide a comprehensive treatment of the asymptotic theory for cepstral random field models. In particular, we provide recursive formulas that connect the spatial cepstral coefficients to an equivalent moving-average random field, which facilitates easy computation of the necessary autocovariance matrix. Additionally, we establish asymptotic consistency results for Bayesian, maximum likelihood, and quasi-maximum likelihood estimation. Further, in both the maximum and quasi-maximum likelihood frameworks we derive the asymptotic distribution of our estimator. The theoretical results are presented gen...

  9. Levy random walks on multiplex networks

    CERN Document Server

    Guo, Quantong; Zheng, Zhiming; Moreno, Yamir

    2016-01-01

    Random walks constitute a fundamental mechanism for many dynamics taking place on complex networks. Besides, as a more realistic description of our society, multiplex networks have been receiving a growing interest, as well as the dynamical processes that occur on top of them. Here, inspired by one specific model of random walks that seems to be ubiquitous across many scientific fields, the Levy flight, we study a new navigation strategy on top of multiplex networks. Capitalizing on spectral graph and stochastic matrix theories, we derive analytical expressions for the mean first passage time and the average time to reach a node on these networks. Moreover, we also explore the efficiency of Levy random walks, which we found to be very different as compared to the single layer scenario, accounting for the structure and dynamics inherent to the multiplex network. Finally, by comparing with some other important random walk processes defined on multiplex networks, we find that in some region of the parameters, a ...

  10. Random point sets and their diffraction

    CERN Document Server

    Baake, Michael

    2010-01-01

    The diffraction of various random subsets of the integer lattice $\\mathbb{Z}^{d}$, such as the coin tossing and related systems, are well understood. Here, we go one important step beyond and consider random point sets in $\\mathbb{R}^{d}$. We present several systems with an effective stochastic interaction that still allow for explicit calculations of the autocorrelation and the diffraction measure. We concentrate on one-dimensional examples for illustrative purposes, and briefly indicate possible generalisations to higher dimensions. In particular, we discuss the stationary Poisson process in $\\mathbb{R}^{d}$ and the renewal process on the line. The latter permits a unified approach to a rather large class of one-dimensional structures, including random tilings. Moreover, we present some stationary point processes that are derived from the classical random matrix ensembles as introduced in the pioneering work of Dyson and Ginibre. Their re-consideration from the diffraction point of view improves the intuiti...

  11. Dissertation: Geodesics of Random Riemannian Metrics

    CERN Document Server

    LaGatta, Tom

    2011-01-01

    We introduce Riemannian First-Passage Percolation (Riemannian FPP) as a new model of random differential geometry, by considering a random, smooth Riemannian metric on $\\mathbb R^d$. We are motivated in our study by the random geometry of first-passage percolation (FPP), a lattice model which was developed to model fluid flow through porous media. By adapting techniques from standard FPP, we prove a shape theorem for our model, which says that large balls under this metric converge to a deterministic shape under rescaling. As a consequence, we show that smooth random Riemannian metrics are geodesically complete with probability one. In differential geometry, geodesics are curves which locally minimize length. They need not do so globally: consider great circles on a sphere. For lattice models of FPP, there are many open questions related to minimizing geodesics; similarly, it is interesting from a geometric perspective when geodesics are globally minimizing. In the present study, we show that for any fixed st...

  12. Blinding in randomized clinical trials: imposed impartiality

    DEFF Research Database (Denmark)

    Hróbjartsson, A; Boutron, I

    2011-01-01

    Blinding, or "masking," is a crucial method for reducing bias in randomized clinical trials. In this paper, we review important methodological aspects of blinding, emphasizing terminology, reporting, bias mechanisms, empirical evidence, and the risk of unblinding. Theoretical considerations and...

  13. Phase Transition in Unrestricted Random SAT

    CERN Document Server

    Schuh, Bernd R

    2012-01-01

    For random CNF formulae with m clauses, n variables and an unrestricted number of literals per clause the transition from high to low satisfiability can be determined exactly for large n. The critical density m/n turns out to be strongly n-dependent, ccr = ln(2)/(1-p)^^n, where pn is the mean number of positive literals per clause.This is in contrast to restricted random SAT problems (random K-SAT), where the critical ratio m/n is a constant. All transition lines are calculated by the second moment method applied to the number of solutions N of a formula. In contrast to random K-SAT, the method does not fail for the unrestricted model, because long range interactions between solutions are not cut off by disorder.

  14. RANDOM WEIGHTING METHOD FOR CENSORED REGRESSION MODEL

    Institute of Scientific and Technical Information of China (English)

    ZHAO Lincheng; FANG Yixin

    2004-01-01

    Rao and Zhao (1992) used random weighting method to derive the approximate distribution of the M-estimator in linear regression model. In this paper we extend the result to the censored regression model (or censored "Tobit" model).

  15. Random Life Curves for Common Engineering Materials

    Science.gov (United States)

    Hu, T.

    1983-01-01

    Program incorporates non-Rayleigh effects in evaluating structure life. RMS2 computer program converts constant amplitude fatigue allowables to random-loading allowables, with influence of peak distribution and mean stress considered. RMS2 written in FORTRAN IV.

  16. Handbook of Large-Scale Random Networks

    CERN Document Server

    Bollobas, Bela; Miklos, Dezso

    2008-01-01

    Covers various aspects of large-scale networks, including mathematical foundations and rigorous results of random graph theory, modeling and computational aspects of large-scale networks, as well as areas in physics, biology, neuroscience, sociology and technical areas

  17. Concentration for noncommutative polynomials in random matrices

    OpenAIRE

    Meckes, Mark W.; Szarek, Stanislaw J.

    2011-01-01

    We present a concentration inequality for linear functionals of noncommutative polynomials in random matrices. Our hypotheses cover most standard ensembles, including Gaussian matrices, matrices with independent uniformly bounded entries and unitary or orthogonal matrices.

  18. Uniform dimension results for Gaussian random fields

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Let X = {X(t),t ∈ RN} be a Gaussian random field with values in Rd defined by X(t) =(X1(t),...,Xd(t)), t ∈ RN.(1) The properties of space and time anisotropy of X and their connections to uniform Hausdorff dimension results are discussed.It is shown that in general the uniform Hausdorff dimension result does not hold for the image sets of a space-anisotropic Gaussian random field X.When X is an(N,d)-Gaussian random field as in(1),where X1,...,Xd are independent copies of a real valued,centered Gaussian random field X0 which is anisotropic in the time variable.We establish uniform Hausdorff dimension results for the image sets of X.These results extend the corresponding results on one-dimensional Brownian motion,fractional Brownian motion and the Brownian sheet.

  19. Spatial coherence of random laser emission.

    Science.gov (United States)

    Redding, Brandon; Choma, Michael A; Cao, Hui

    2011-09-01

    We experimentally studied the spatial coherence of random laser emission from dye solutions containing nanoparticles. The spatial coherence, measured in a double slit experiment, varied significantly with the density of scatterers and the size and shape of the excitation volume. A qualitative explanation is provided, illustrating the dramatic difference from the spatial coherence of a conventional laser. This work demonstrates that random lasers can be controlled to provide intense, spatially incoherent emission for applications in which spatial cross talk or speckle limit performance.

  20. Randomness and Criticality in Biological Interactions

    OpenAIRE

    Grilli, Jacopo

    2015-01-01

    In this thesis we study from a physics perspective two problems related to biological interactions. In the first part of this thesis we consider ecological interactions, that shape ecosystems and determine their fate, and their relation with stability of ecosystems. Using random matrix theory we are able to identify the key aspect, the order parameters, determining the stability of large ecosystems. We then consider the problem of determining the persistence of a population living in a random...

  1. Managing numerical errors in random sequential adsorption

    Science.gov (United States)

    Cieśla, Michał; Nowak, Aleksandra

    2016-09-01

    Aim of this study is to examine the influence of a finite surface size and a finite simulation time on a packing fraction estimated using random sequential adsorption simulations. The goal of particular interest is providing hints on simulation setup to achieve desired level of accuracy. The analysis is based on properties of saturated random packing of disks on continuous and flat surfaces of different sizes.

  2. (Convertible) Undeniable Signatures Without Random Oracles

    Science.gov (United States)

    Yuen, Tsz Hon; Au, Man Ho; Liu, Joseph K.; Susilo, Willy

    We propose a convertible undeniable signature scheme without random oracles. Our construction is based on Waters' and Kurosawa and Heng's schemes that were proposed in Eurocrypt 2005. The security of our scheme is based on the CDH and the decision linear assumption. Comparing only the part of undeniable signatures, our scheme uses more standard assumptions than the existing undeniable signatures without random oracles due to Laguillamie and Vergnaud.

  3. Tempered stable laws as random walk limits

    OpenAIRE

    Chakrabarty, Arijit; Meerschaert, Mark M.

    2010-01-01

    Stable laws can be tempered by modifying the L\\'evy measure to cool the probability of large jumps. Tempered stable laws retain their signature power law behavior at infinity, and infinite divisibility. This paper develops random walk models that converge to a tempered stable law under a triangular array scheme. Since tempered stable laws and processes are useful in statistical physics, these random walk models can provide a basic physical model for the underlying physical phenomena.

  4. Communication Requirements for Generating Correlated Random Variables

    CERN Document Server

    Cuff, Paul

    2008-01-01

    Two familiar notions of correlation are rediscovered as extreme operating points for simulating a discrete memoryless channel, in which a channel output is generated based only on a description of the channel input. Wyner's "common information" coincides with the minimum description rate needed. However, when common randomness independent of the input is available, the necessary description rate reduces to Shannon's mutual information. This work characterizes the optimal tradeoff between the amount of common randomness used and the required rate of description.

  5. Design of Reversible Random Access Memory

    OpenAIRE

    Mamun, Md. Selim Al; Hossain, Syed Monowar

    2013-01-01

    Reversible logic has become immensely popular research area and its applications have spread in various technologies for their low power consumption. In this paper we proposed an efficient design of random access memory using reversible logic. In the way of designing the reversible random access memory we proposed a reversible decoder and a write enable reversible master slave D flip-flop. All the reversible designs are superior in terms of quantum cost, delay and garbage outputs compared to ...

  6. Quantum random walks - an introductory overview

    CERN Document Server

    Kempe, J

    2003-01-01

    This article aims to provide an introductory survey on quantum random walks. Starting from a physical effect to illustrate the main ideas we will introduce quantum random walks, review some of their properties and outline their striking differences to classical walks. We will touch upon both physical effects and computer science applications, introducing some of the main concepts and language of present day quantum information science in this context. We will mention recent developments in this new area and outline some open questions.

  7. Time-reversal symmetry and random polynomials

    OpenAIRE

    Braun, D; Kus, M.; Zyczkowski, K.

    1996-01-01

    We analyze the density of roots of random polynomials where each complex coefficient is constructed of a random modulus and a fixed, deterministic phase. The density of roots is shown to possess a singular component only in the case for which the phases increase linearly with the index of coefficients. This means that, contrary to earlier belief, eigenvectors of a typical quantum chaotic system with some antiunitary symmetry will not display a clustering curve in the stellar representation. M...

  8. Bell Experiments with Random Destination Sources

    OpenAIRE

    Sciarrino, F.; Vallone, G.; Cabello, A.; Mataloni, P.

    2010-01-01

    It is generally assumed that sources sending randomly two particles to one or two different observers, named here random destination sources (RDS), cannot by used for genuine quantum nonlocality tests because of the postselection loophole. We demonstrate that Bell experiments not affected by the postselection loophole may be performed with: (i) RDS and local postselection using perfect detectors, (ii) RDS, local postselection, and fair sampling assumption with any detection efficiency, and (i...

  9. A random matrix approach to decoherence

    CERN Document Server

    Gorin, T; Gorin, Thomas; Seligman, Thomas H.

    2001-01-01

    In order to analyze the effect of chaos or order on the rate of decoherence in a subsystem, we aim to distinguish effects of the two types of dynamics by choosing initial states as random product states from two factor spaces representing two subsystems. We introduce a random matrix model that permits to vary the coupling strength between the subsystems. The case of strong coupling is analyzed in detail, and we find no significant differences except for very low-dimensional spaces.

  10. Dissipative Quasigeostrophic Dynamics under Random Forcing

    OpenAIRE

    Brannan, James R.; Duan, Jinqiao; Wanner, Thomas

    1998-01-01

    The quasigeostrophic model is a simplified geophysical fluid model at asymptotically high rotation rate or at small Rossby number. We consider the quasigeostrophic equation with dissipation under random forcing in bounded domains. We show that global unique solutions exist for appropriate initial data. Unlike the deterministic quasigeostrophic equation whose well-posedness is well-known, there seems no rigorous result on global existence and uniqueness of the randomly forced quasigeostrophic ...

  11. Dynamics of excitable nodes on random graphs

    Indian Academy of Sciences (India)

    K Manchanda; T Umeshkanta Singh; R Ramaswamy

    2011-11-01

    We study the interplay of topology and dynamics of excitable nodes on random networks. Comparison is made between systems grown by purely random (Erd˝os–Rényi) rules and those grown by the Achlioptas process. For a given size, the growth mechanism affects both the thresholds for the emergence of different structural features as well as the level of dynamical activity supported on the network.

  12. On a directionally reinforced random walk

    CERN Document Server

    Ghosh, Arka; Roitershtein, Alexander

    2011-01-01

    We consider a generalized version of a directionally reinforced random walk, which was originally introduced by Mauldin, Monticino, and von Weizs\\"{a}cker in \\cite{drw}. Our main result is a stable limit theorem for the position of the random walk in higher dimensions. This extends a result of Horv\\'{a}th and Shao \\cite{limits} that was previously obtained in dimension one only (however, in a more stringent functional form).

  13. Random right eigenvalues of Gaussian quaternionic matrices

    CERN Document Server

    Benaych-Georges, Florent

    2011-01-01

    We consider a random matrix whose entries are independent Gaussian variables taking values in the field of quaternions with variance $1/n$. Using logarithmic potential theory, we prove the almost sure convergence, as the dimension $n$ goes to infinity, of the empirical distribution of the right eigenvalues towards some measure supported on the unit ball of the quaternions field. Some comments on more general Gaussian quaternionic random matrix models are also made.

  14. Some Properties of the Random Universe

    OpenAIRE

    Scoville, Anthony E.

    2002-01-01

    What is the role of the constants of nature in physical theory? I hypothesize that the observable universe, u0, constitutes a Universal Turing Machine (UTM) constrained by algorithmically random logical tape parameters defining its material properties (a physical UTM). The finite non-zero empirical values of Planck's constant, h, and other constants of nature exemplify those logical parameters. Their algorithmic randomness is necessary and sufficient for the consistent operation of a physical...

  15. On stability of Random Riccati equations

    Institute of Scientific and Technical Information of China (English)

    王远; 郭雷

    1999-01-01

    Random Riccati equations (RRE) arise frequently in filtering, estimation and control, but their stability properties are rarely rigorously explored in the literature. First a suitable stochastic observability (or excitation) condition is introduced to guarantee both the L_r-and exponential stability of RRE. Then the stability of Kalman filter is analyzed with random coefficients, and the L_r boundedness of filtering errors is established.

  16. Contextuality is about identity of random variables

    Science.gov (United States)

    Dzhafarov, Ehtibar N.; Kujala, Janne V.

    2014-12-01

    Contextual situations are those in which seemingly ‘the same’ random variable changes its identity depending on the conditions under which it is recorded. Such a change of identity is observed whenever the assumption that the variable is one and the same under different conditions leads to contradictions when one considers its joint distribution with other random variables (this is the essence of all Bell-type theorems). In our Contextuality-by-Default approach, instead of asking why or how the conditions force ‘one and the same’ random variable to change ‘its’ identity, any two random variables recorded under different conditions are considered different ‘automatically.’ They are never the same, nor are they jointly distributed, but one can always impose on them a joint distribution (probabilistic coupling). The special situations when there is a coupling in which these random variables are equal with probability 1 are considered noncontextual. Contextuality means that such couplings do not exist. We argue that the determination of the identity of random variables by conditions under which they are recorded is not a causal relationship and cannot violate laws of physics.

  17. k-Connectivity of Random Key Graphs

    CERN Document Server

    Zhao, Jun; Gligor, Virgil

    2015-01-01

    Random key graphs represent topologies of secure wireless sensor networks that apply the seminal Eschenauer-Gligor random key predistribution scheme to secure communication between sensors. These graphs have received much attention and also been used in diverse application areas beyond secure sensor networks; e.g., cryptanalysis, social networks, and recommender systems. Formally, a random key graph with $n$ nodes is constructed by assigning each node $X_n$ keys selected uniformly at random from a pool of $Y_n$ keys and then putting an undirected edge between any two nodes sharing at least one key. Considerable progress has been made in the literature to analyze connectivity and $k$-connectivity of random key graphs, where $k$-connectivity of a graph ensures connectivity even after the removal of $k$ nodes or $k$ edges. Yet, it still remains an open question for $k$-connectivity in random key graphs under $X_n \\geq 2$ and $X_n = o(\\sqrt{\\ln n})$ (the case of $X_n=1$ is trivial). In this paper, we answer the a...

  18. Application of Vector Triggering Random Decrement

    DEFF Research Database (Denmark)

    Asmussen, J. C.; Ibrahim, S. R.; Brincker, Rune

    1997-01-01

    This paper deals with applications of the vector triggering Random Decrement technique. This technique is new and developed with the aim of minimizing estimation time and identification errors. The theory behind the technique is discussed in an accompanying paper. The results presented in this pa......This paper deals with applications of the vector triggering Random Decrement technique. This technique is new and developed with the aim of minimizing estimation time and identification errors. The theory behind the technique is discussed in an accompanying paper. The results presented...... result is a Random Decrement function from each measurement. In traditional Random Decrement estimation the triggering condition is a scalar condition, which should only be fulfilled in a single measurement. In vector triggering Random Decrement the triggering condition is a vector condition....... The advantage of this new approach should be a reduction in estimation time without a significant loss of accuracy, since the vector triggering conditions ensure cross information between the measurements in the Random Decrement functions. The different problems with this technique is highlighted in two...

  19. Application of Vector Triggering Random Decrement

    DEFF Research Database (Denmark)

    Asmussen, J. C.; Ibrahim, S. R.; Brincker, Rune

    This paper deals with applications of the vector triggering Random Decrement technique. This technique is new and developed with the aim of minimizing estimation time and identification errors. The theory behind the technique is discussed in an accompanying paper. The results presented in this pa......This paper deals with applications of the vector triggering Random Decrement technique. This technique is new and developed with the aim of minimizing estimation time and identification errors. The theory behind the technique is discussed in an accompanying paper. The results presented...... result is a Random Decrement function from each measurement. In traditional Random Decrement estimation the triggering condition is a scalar condition, which should only be fulfilled in a single measurement. In vector triggering Random Decrement the triggering condition is a vector condition....... The advantage of this new approach should be a reduction in estimation time without a significant loss of accuracy, since the vector triggering conditions ensure cross information between the measurements in the Random Decrement functions. The different problems with this technique is highlighted in two...

  20. Enhancing superconducting critical current by randomness.

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Y. L.; Thoutam, L. R.; Xiao, Z. L.; Shen, B.; Pearson, J.; Divan, R.; Ocola, L. E.; Crabtree, G. W.; Kwok, W. K.

    2016-01-11

    The key ingredient of high critical currents in a type-II superconductor is defect sites that pin vortices. Here, we demonstrate that a random pinscape, an overlooked pinning system in nanopatterned superconductors, can lead to a substantially larger critical current enhancement at high magnetic fields than an ordered array of vortex pin sites. We reveal that the better performance of a random pinscape is due to the variation of the local density of its pinning sites, which mitigates the motion of vortices. This is confirmed by achieving even higher enhancement of the critical current through a conformally mapped random pinscape, where the distribution of the local density of pinning sites is further enlarged. Our findings highlight the potential of random pinscapes in enhancing the superconducting critical currents of applied superconductors in which random pin sites of nanoscale defects emerging in the materials synthesis process or through ex-situ irradiation are the only practical choice for large-scale production. Our results may also stimulate research on effects of a random pinscape in other complementary systems such as colloidal crystals, Bose-Einstein condensates, and Luttinger liquids.

  1. Random Oracles in a Quantum World

    CERN Document Server

    Dagdelen, Özgür; Lehmann, Anja; Schaffner, Christian

    2010-01-01

    Once quantum computers reach maturity most of today's traditional cryptographic schemes based on RSA or discrete logarithms become vulnerable to quantum-based attacks. Hence, schemes which are more likely to resist quantum attacks like lattice-based systems or code-based primitives have recently gained significant attention. Interestingly, a vast number of such schemes also deploy random oracles, which have mainly be analyzed in the classical setting. Here we revisit the random oracle model in cryptography in light of quantum attackers. We show that there are protocols using quantum-immune primitives and random oracles, such that the protocols are secure in the classical world, but insecure if a quantum attacker can access the random oracle via quantum states. We discuss that most of the proof techniques related to the random oracle model in the classical case cannot be transferred immediately to the quantum case. Yet, we show that ``quantum random oracles'' can nonetheless be used to show for example that th...

  2. Statistical properties of randomization in clinical trials.

    Science.gov (United States)

    Lachin, J M

    1988-12-01

    This is the first of five articles on the properties of different randomization procedures used in clinical trials. This paper presents definitions and discussions of the statistical properties of randomization procedures as they relate to both the design of a clinical trial and the statistical analysis of trial results. The subsequent papers consider, respectively, the properties of simple (complete), permuted-block (i.e., blocked), and urn (adaptive biased-coin) randomization. The properties described herein are the probabilities of treatment imbalances and the potential effects on the power of statistical tests; the permutational basis for statistical tests; and the potential for experimental biases in the assessment of treatment effects due either to the predictability of the random allocations (selection bias) or the susceptibility of the randomization procedure to covariate imbalances (accidental bias). For most randomization procedures, the probabilities of overall treatment imbalances are readily computed, even when a stratified randomization is used. This is important because treatment imbalance may affect statistical power. It is shown, however, that treatment imbalance must be substantial before power is more than trivially affected. The differences between a population versus a permutation model as a basis for a statistical test are reviewed. It is argued that a population model can only be invoked in clinical trials as an untestable assumption, rather than being formally based on sampling at random from a population. On the other hand, a permutational analysis based on the randomization actually employed requires no assumptions regarding the origin of the samples of patients studied. The large sample permutational distribution of the family of linear rank tests is described as a basis for easily conducting a variety of permutation tests. Subgroup (stratified) analyses, analyses when some data are missing, and regression model analyses are also

  3. Law of large numbers for a class of random walks in dynamic random environments

    CERN Document Server

    Avena, L; Redig, F

    2009-01-01

    In this paper we consider a class of one-dimensional interacting particle systems in equilibrium, constituting a dynamic random environment, together with a nearest-neighbor random walk that on occupied/vacant sites has a local drift to the right/left. We adapt a regeneration-time argument originally developed by Comets and Zeitouni for static random environments to prove that, under a space-time mixing property for the dynamic random environment called cone-mixing, the random walk has an a.s. constant global speed. In addition, we show that if the dynamic random environment is exponentially mixing in space-time and the local drifts are small, then the global speed can be written as a power series in the size of the local drifts. From the first term in this series the sign of the global speed can be read off. The results can be easily extended to higher dimensions.

  4. Analyzing Nonstationary Random Response of a SDOF System under the Evolutionary Random Excitation by Wavelet Transform

    Institute of Scientific and Technical Information of China (English)

    LI Fang-bing; ZHANG Tian-shu

    2006-01-01

    For evolutionary random excitations, a general method of analyzing nonstationary random responses of systems was presented in this paper. Firstly, for the evolutionary random excitation model, the evolutionary power spectrum density function (EPSD) of a random excitation was given by wavelet transform. Based on the EPSD, the nonstationary responses of a SDOF system subjected to evolutionary random excitations were studied. The application and validity of presented method were illustrated by numerical examples. In numerical examples, the recently developed stochastic models for EI Contro (1934) and Mexico City (1985) earthquakes which preserve the nonstationary evolutions of amplitude and frequency content of ground accelerations were used as excitations. The nonstationary random mean-square responses of a SDOF system under these two excitations were evaluated and compared with simulated results.

  5. Existence of the harmonic measure for random walks on graphs and in random environments

    CERN Document Server

    Boivin, Daniel

    2011-01-01

    We give a sufficient condition for the existence of the harmonic measure from infinity of transient random walks on weighted graphs. In particular, this condition is verified by the random conductance model on $\\Z^d$, $d\\geq 3$, when the conductances are i.i.d. and the bonds with positive conductance percolate. The harmonic measure from infinity also exists for random walks on supercritical clusters of ${\\mathbb Z}^2$. This is proved using results of Barlow (2004).

  6. Applying Free Random Variables to Random Matrix Analysis of Financial Data

    CERN Document Server

    Burda, Z; Jurkiewicz, J; Nowak, M A; Papp, G; Zahed, I

    2006-01-01

    We apply the concept of free random variables to correlated Wishart random matrix models. We give a comprehensive rederivation of various spectral densities for a number of financial covariance matrices involving stocks returns without and with exponentially weighted moving averages. We show through simple models how to identify the pertinent underlying correlations. We extend our results to Levy-Wishart random matrix models whereby the risk factors are heavy tailed.

  7. Two spatial light modulator system for laboratory simulation of random beam propagation in random media.

    Science.gov (United States)

    Wang, Fei; Toselli, Italo; Korotkova, Olga

    2016-02-10

    An optical system consisting of a laser source and two independent consecutive phase-only spatial light modulators (SLMs) is shown to accurately simulate a generated random beam (first SLM) after interaction with a stationary random medium (second SLM). To illustrate the range of possibilities, a recently introduced class of random optical frames is examined on propagation in free space and several weak turbulent channels with Kolmogorov and non-Kolmogorov statistics. PMID:26906385

  8. Two spatial light modulator system for laboratory simulation of random beam propagation in random media.

    Science.gov (United States)

    Wang, Fei; Toselli, Italo; Korotkova, Olga

    2016-02-10

    An optical system consisting of a laser source and two independent consecutive phase-only spatial light modulators (SLMs) is shown to accurately simulate a generated random beam (first SLM) after interaction with a stationary random medium (second SLM). To illustrate the range of possibilities, a recently introduced class of random optical frames is examined on propagation in free space and several weak turbulent channels with Kolmogorov and non-Kolmogorov statistics.

  9. Large deviations for heavy-tailed random sums of independent random variables with dominatedly varying tails

    Institute of Scientific and Technical Information of China (English)

    LIU; Yan(刘艳); HU; Yijun(胡亦钧)

    2003-01-01

    We prove large deviation results on the partial and random sums Sn = ∑ni=1 Xi, n≥1; S(t) =∑N(t)i=1 Xi, t≥0, where {N(t);t≥0} are non-negative integer-valued random variables and {Xn;n≥1} areindependent non-negative random variables with distribution, Fn, of Xn, independent of {N(t); t≥0}. Specialattention is paid to the distribution of dominated variation.

  10. An Unbiased Estimator of the Variance of Simple Random Sampling Using Mixed Random-Systematic Sampling

    OpenAIRE

    Padilla, Alberto

    2009-01-01

    Systematic sampling is a commonly used technique due to its simplicity and ease of implementation. The drawback of this simplicity is that it is not possible to estimate the design variance without bias. There are several ways to circumvent this problem. One method is to suppose that the variable of interest has a random order in the population, so the sample variance of simple random sampling without replacement is used. By means of a mixed random - systematic sample, an unbiased estimator o...

  11. Creating order with the help of randomness: generating transversely random, longitudinally invariant vector optical fields.

    Science.gov (United States)

    Khonina, Svetlana N; Golub, Ilya

    2015-09-01

    We show that it is possible to generate transversely random, diffraction-free/longitudinally invariant vector optical fields. The randomness in transverse polarization distribution complements a previously studied one in intensity of scalar Bessel-type beams, adding another degree of freedom to control these beams. Moreover, we show that the relative transversely random phase distribution is also conserved along the optical axis. Thus, intensity, phase, and polarization of Bessel-type beams can be transversely random/arbitrary while invariant upon propagation. Such fields may find applications in encryption/secure communications, optical trapping, etc. PMID:26368714

  12. Level 1 quenched large deviation principle for random walk in dynamic random environment

    CERN Document Server

    Drewitz, David Campos Alexander

    2011-01-01

    Consider a random walk on a continuous time-dependent random environment on the hiper-cubic lattice. Recently, Rassoul-Agha, Seppalainen and Yilmaz proved a general large deviation principle under mild ergodicity assumptions on the random environment for such a random walk, establishing first a level 2 and 3 large deviation principle. Here we present an alternative short proof of the level 1 large deviations under mild ergodicity assumptions on the environment, which provides the existence and convexity of the rate function, in the continuous time case. Our methods are based on the use of sub-additive ergodic theorem as presented by Varadhan in 2003.

  13. SEISMIC RANDOM VIBRATION ANALYSIS OF STOCHASTIC STRUCTURES USING RANDOM FACTOR METHOD

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Seismic random vibration analysis of stochastic truss structures is presented. A new method called random factor method is used for dynamic analysis of structures with uncertain parameters, due to variability in their material properties and geometry. Using the random factor method, the natural frequencies and modeshapes of a stochastic structure can be respectively described by the product of two parts, corresponding to the random factors of the structural parameters with uncertainty, and deterministic values of the natural frequencies and modeshapes obtained by conventional finite element analysis. The stochastic truss structure is subjected to stationary or non-stationary random earthquake excitation. Computational expressions for the mean and standard deviation of the mean square displacement and mean square stress are developed by means of the random variable's functional moment method and the algebra synthesis method. An antenna and a truss bridge are used as practical engineering examples to illustrate the application of the random factor method in the seismic response analysis of random structures under stationary or non-stationary random earthquake excitation.

  14. Scaling Argument of Anisotropic Random Walk

    Institute of Scientific and Technical Information of China (English)

    XU Bing-Zhen; JIN Guo-Jun; WANG Fei-Feng

    2005-01-01

    In this paper, we analytically discuss the scaling properties of the average square end-to-end distance for anisotropic random walk in D-dimensional space ( D ≥ 2), and the returning probability Pn(ro) for the walker into a certain neighborhood of the origin. We will not only give the calculating formula for and Pn (ro), but also point out that if there is a symmetric axis for the distribution of the probability density of a single step displacement, we always obtain ~ n, where ⊥ refers to the projections of the displacement perpendicular to each symmetric axes of the walk; in D-dimensional space with D symmetric axes perpendicular to each other, we always have ~ n and the random walk will be like a purely random motion; if the number of inter-perpendicular symmetric axis is smaller than the dimensions of the space, we must have ~ n2 for very large n and the walk will be like a ballistic motion. It is worth while to point out that unlike the isotropic random walk in one and two dimensions, which is certain to return into the neighborhood of the origin, generally there is only a nonzero probability for the anisotropic random walker in two dimensions to return to the neighborhood.

  15. Randomized central limit theorems: A unified theory

    Science.gov (United States)

    Eliazar, Iddo; Klafter, Joseph

    2010-08-01

    The central limit theorems (CLTs) characterize the macroscopic statistical behavior of large ensembles of independent and identically distributed random variables. The CLTs assert that the universal probability laws governing ensembles’ aggregate statistics are either Gaussian or Lévy, and that the universal probability laws governing ensembles’ extreme statistics are Fréchet, Weibull, or Gumbel. The scaling schemes underlying the CLTs are deterministic—scaling all ensemble components by a common deterministic scale. However, there are “random environment” settings in which the underlying scaling schemes are stochastic—scaling the ensemble components by different random scales. Examples of such settings include Holtsmark’s law for gravitational fields and the Stretched Exponential law for relaxation times. In this paper we establish a unified theory of randomized central limit theorems (RCLTs)—in which the deterministic CLT scaling schemes are replaced with stochastic scaling schemes—and present “randomized counterparts” to the classic CLTs. The RCLT scaling schemes are shown to be governed by Poisson processes with power-law statistics, and the RCLTs are shown to universally yield the Lévy, Fréchet, and Weibull probability laws.

  16. Random subspaces in quantum information theory

    Science.gov (United States)

    Hayden, Patrick

    2005-03-01

    The selection of random unitary transformations plays a role in quantum information theory analogous to the role of random hash functions in classical information theory. Recent applications have included protocols achieving the quantum channel capacity and methods for extending superdense coding from bits to qubits. In addition, the corresponding random subspaces have proved useful for studying the structure of bipartite and multipartite entanglement. In quantum information theory, we're fond of saying that Hilbert space is a big place, the implication being that there's room for the unexpected to occur. The goal of this talk is to further bolster this homespun wisdowm. I'm going to present a number of results in quantum information theory that stem from the initially counterintuitive geometry of high-dimensional vector spaces, where subspaces with highly extremal properties are the norm rather than the exception. Peter Shor has shown, for example, that randomly selected subspaces can be used to send quantum information through a noisy quantum channel at the highest possible rate, that is, the quantum channel capacity. More recently, Debbie Leung, Andreas Winter and I demonstrated that a randomly chosen subspace of a bipartite quantum system will likely contain nothing but nearly maximally entangled states, even if the subspace is nearly as large as the original system in qubit terms. This observation has implications for communication, especially superdense coding.

  17. Coupled continuous time random walks in finance

    CERN Document Server

    Meerschaert, M M; Meerschaert, Mark M.; Scalas, Enrico

    2006-01-01

    Continuous time random walks (CTRWs) are used in physics to model anomalous diffusion, by incorporating a random waiting time between particle jumps. In finance, the particle jumps are log-returns and the waiting times measure delay between transactions. These two random variables (log-return and waiting time) are typically not independent. For these coupled CTRW models, we can now compute the limiting stochastic process (just like Brownian motion is the limit of a simple random walk), even in the case of heavy tailed (power-law) price jumps and/or waiting times. The probability density functions for this limit process solve fractional partial differential equations. In some cases, these equations can be explicitly solved to yield descriptions of long-term price changes, based on a high-resolution model of individual trades that includes the statistical dependence between waiting times and the subsequent log-returns. In the heavy tailed case, this involves operator stable space-time random vectors that genera...

  18. Hardware Random number Generator for cryptography

    CERN Document Server

    Soorat, Ram; Vudayagiri, Ashok

    2015-01-01

    One of the key requirement of many schemes is that of random numbers. Sequence of random numbers are used at several stages of a standard cryptographic protocol. A simple example is of a Vernam cipher, where a string of random numbers is added to massage string to generate the encrypted code. It is represented as $C=M \\oplus K $ where $M$ is the message, $K$ is the key and $C$ is the ciphertext. It has been mathematically shown that this simple scheme is unbreakable is key K as long as M and is used only once. For a good cryptosystem, the security of the cryptosystem is not be based on keeping the algorithm secret but solely on keeping the key secret. The quality and unpredictability of secret data is critical to securing communication by modern cryptographic techniques. Generation of such data for cryptographic purposes typically requires an unpredictable physical source of random data. In this manuscript, we present studies of three different methods for producing random number. We have tested them by study...

  19. Random Number Generator Using Seven Segment Display In Labview

    OpenAIRE

    D. Bhavana; D.Ravi Tej

    2015-01-01

    Random number generator [RNG] is use to generate random numbers between any given limit, RNG's are two kinds 1.True random number and 2.pseudom numbers. True random numbers are not predictable by any mathematical formula because they are mainly depends on the atmospheric noise, coming to the pseudo numbers are mainly used in most of computers, this randomness can be predictable by using mathematical formula and it is fine many purposes, but it may not be random in the way you expe...

  20. Rationale and design of a multicenter randomized controlled trial on a 'minimal intervention' in Dutch army personnel with nonspecific low back pain [ISRCTN19334317

    Directory of Open Access Journals (Sweden)

    Staal J Bart

    2004-11-01

    Full Text Available Abstract Background Researchers from the Royal Netherlands Army are studying the potential of isolated lumbar extensor training in low back pain in their working population. Currently, a randomized controlled trial is carried out in five military health centers in The Netherlands and Germany, in which a 10-week program of not more than 2 training sessions (10–15 minutes per week is studied in soldiers with nonspecific low back pain for more than 4 weeks. The purpose of the study is to investigate the efficacy of this 'minimal intervention program', compared to usual care. Moreover, attempts are made to identify subgroups of different responders to the intervention. Methods Besides a baseline measurement, follow-up data are gathered at two short-term intervals (5 and 10 weeks after randomization and two long-term intervals (6 months and one year after the end of the intervention, respectively. At every test moment, participants fill out a compound questionnaire on a stand-alone PC, and they undergo an isometric back strength measurement on a lower back machine. Primary outcome measures in this study are: self-assessed degree of complaints and degree of handicap in daily activities due to back pain. In addition, our secondary measurements focus on: fear of movement/(re- injury, mental and social health perception, individual back extension strength, and satisfaction of the patient with the treatment perceived. Finally, we assess a number of potential prognostic factors: demographic and job characteristics, overall health, the degree of physical activity, and the attitudes and beliefs of the physiotherapist towards chronic low back pain. Discussion Although a substantial number of trials have been conducted that included lumbar extension training in low back pain patients, hardly any study has emphasized a minimal intervention approach comparable to ours. For reasons of time efficiency and patient preferences, this minimal sports medicine

  1. Effect of Workplace- versus Home-Based Physical Exercise on Muscle Response to Sudden Trunk Perturbation among Healthcare Workers: A Cluster Randomized Controlled Trial

    Directory of Open Access Journals (Sweden)

    Markus D. Jakobsen

    2015-01-01

    Full Text Available Objectives. The present study investigates the effect of workplace- versus home-based physical exercise on muscle reflex response to sudden trunk perturbation among healthcare workers. Methods. Two hundred female healthcare workers (age: 42 [SD 11], BMI: 24 [SD 4], and pain intensity: 3.1 [SD 2.2] on a scale of 0–10 from 18 departments at three hospitals were randomized at the cluster level to 10 weeks of (1 workplace physical exercise (WORK performed in groups during working hours for 5 × 10 minutes per week and up to 5 group-based coaching sessions on motivation for regular physical exercise, or (2 home-based physical exercise (HOME performed during leisure time for 5 × 10 minutes per week. Mechanical and neuromuscular (EMG response to randomly assigned unloading and loading trunk perturbations and questions of fear avoidance were assessed at baseline and 10-week follow-up. Results. No group by time interaction for the mechanical trunk response and EMG latency time was seen following the ten weeks (P = 0.17–0.75. However, both groups demonstrated within-group changes (P<0.05 in stopping time during the loading and unloading perturbation and in stopping distance during the loading perturbation. Furthermore, EMG preactivation of the erector spinae and fear avoidance were reduced more following WORK than HOME (95% CI −2.7–−0.7 (P<0.05 and −0.14 (−0.30 to 0.02 (P=0.09, respectively. WORK and HOME performed 2.2 (SD: 1.1 and 1.0 (SD: 1.2 training sessions per week, respectively. Conclusions. Although training adherence was higher following WORK compared to HOME this additional training volume did not lead to significant between-group differences in the responses to sudden trunk perturbations. However, WORK led to reduced fear avoidance and reduced muscle preactivity prior to the perturbation onset, compared with HOME. This trial is registered with Clinicaltrials.gov (NCT01921764.

  2. Interpreting parameters in the logistic regression model with random effects

    DEFF Research Database (Denmark)

    Larsen, Klaus; Petersen, Jørgen Holm; Budtz-Jørgensen, Esben;

    2000-01-01

    interpretation, interval odds ratio, logistic regression, median odds ratio, normally distributed random effects......interpretation, interval odds ratio, logistic regression, median odds ratio, normally distributed random effects...

  3. FRACTAL DIMENSION RESULTS FOR CONTINUOUS TIME RANDOM WALKS.

    Science.gov (United States)

    Meerschaert, Mark M; Nane, Erkan; Xiao, Yimin

    2013-04-01

    Continuous time random walks impose random waiting times between particle jumps. This paper computes the fractal dimensions of their process limits, which represent particle traces in anomalous diffusion.

  4. Random Assisted Browsing of Rushes Archives

    Directory of Open Access Journals (Sweden)

    Tijana Janjusevic

    2010-04-01

    Full Text Available How to efficiently browse a large video database if its content is unknown to the user? In this paper we propose new approaches for browsing initialisation, exploration and content access of a rushes archive, where the span of information stored can be huge and difficult to understand at a glance. Exploring and navigating through raw footage is assisted by organising the video material in a meaningful structure and by adopting appropriate visualisation solutions. Un-annotated content is organised in hierarchical previews, while browsing is enabled by novel methods of random exploration and random content access to preview nodes. User tests conducted on professional users in a realwork scenario aim at demonstrating how the hierarchical visualisation and the proposed random browsing solutions assist the process of accessing and retrieving desired content.

  5. The entanglement negativity in random spin chains

    CERN Document Server

    Ruggiero, Paola; Calabrese, Pasquale

    2016-01-01

    We investigate the logarithmic negativity in strongly-disordered spin chains in the random-singlet phase. We focus on the spin-1/2 random Heisenberg chain and the random XX chain. We find that for two arbitrary intervals the disorder-averaged negativity and the mutual information are proportional to the number of singlets shared between the two intervals. Using the strong-disorder renormalization group (SDRG), we prove that the negativity of two adjacent intervals grows logarithmically with the intervals length. In particular, the scaling behavior is the same as in conformal field theory, but with a different prefactor. For two disjoint intervals the negativity is given by a universal simple function of the cross ratio, reflecting scale invariance. As a function of the distance of the two intervals, the negativity decays algebraically in contrast with the exponential behavior in clean models. We confirm our predictions using a numerical implementation of the SDRG method. Finally, we also implement DMRG simula...

  6. The randomized complexity of maintaining the minimum

    DEFF Research Database (Denmark)

    Brodal, Gerth Stølting; Chaudhuri, Shiva; Radhakrishnan, Jaikumar

    1996-01-01

    The complexity of maintaining a set under the operations Insert, Delete and FindMin is considered. In the comparison model it is shown that any randomized algorithm with expected amortized cost t comparisons per Insert and Delete has expected cost at least n/(e22t)-1 comparisons for FindMin. If F......The complexity of maintaining a set under the operations Insert, Delete and FindMin is considered. In the comparison model it is shown that any randomized algorithm with expected amortized cost t comparisons per Insert and Delete has expected cost at least n/(e22t)-1 comparisons for Find......Min. If FindMin is replaced by a weaker operation. FindAny, then it is shown that a randomized algorithm with constant expected cost per operation exists; in contrast, it is shown that no deterministic algorithm can have constant cost per operation. Finally, a deterministic algorithm with constant amortized...

  7. Topological properties of random wireless networks

    Indian Academy of Sciences (India)

    Srikanth K Iyer; D Manjunath

    2006-04-01

    Wireless networks in which the node locations are random are best modelled as random geometric graphs (RGGs). In addition to their extensive application in the modelling of wireless networks, RGGs find many new applications and are being studied in their own right. In this paper we first provide a brief introduction to the issues of interest in random wireless networks. We then discuss some recent results for one-dimensional networks with the nodes distributed uniformly in $(0, z)$.We then discuss some asymptotic results for networks in higher dimensions when the nodes are distributed in a finite volume. Finally we discuss some recent generalisations in considering non uniform transmission ranges and non uniform node distributions. An annotated bibliography of some of the recent literature is also provided.

  8. Spectral partitioning of random regular blockmodels

    CERN Document Server

    Barucca, Paolo

    2016-01-01

    Graph partitioning problems emerge in a wide variety of complex systems, ranging from biology to finance, but can be rigorously analyzed and solved only for a few graph ensembles. Here, an ensemble of random graphs with regular block structure is introduced, for which analytical results can be obtained. In particular, the spectral density of such random regular blockmodels is computed exactly for a modular, bipartite and core-periphery structure. McKay's law for random regular graphs is found analytically to apply also for regular modular and bipartite structures when blocks are homogeneous. In core-periphery structures, where blocks are intrinsically heterogeneous, a new law is found to apply for the spectral density. Exact solution to the inference problem is provided for the models discussed. All analytical results show perfect agreement with numerical experiments. Final discussion summarizes results and outlines the relevance of the results for the solution of graph partitioning problems in other graph en...

  9. The evolution of random reversal graph

    CERN Document Server

    Jin, Emma Y

    2010-01-01

    The random reversal graph offers new perspectives, allowing to study the connectivity of genomes as well as their most likely distance as a function of the reversal rate. Our main result shows that the structure of the random reversal graph changes dramatically at $\\lambda_n=1/\\binom{n+1}{2}$. For $\\lambda_n=(1-\\epsilon)/\\binom{n+1}{2}$, the random graph consists of components of size at most $O(n\\ln(n))$ a.s. and for $(1+\\epsilon)/\\binom{n+1}{2}$, there emerges a unique largest component of size $\\sim \\wp(\\epsilon) \\cdot 2^n\\cdot n$!$ a.s.. This "giant" component is furthermore dense in the reversal graph.

  10. Portfolio optimization and the random magnet problem

    Science.gov (United States)

    Rosenow, B.; Plerou, V.; Gopikrishnan, P.; Stanley, H. E.

    2002-08-01

    Diversification of an investment into independently fluctuating assets reduces its risk. In reality, movements of assets are mutually correlated and therefore knowledge of cross-correlations among asset price movements are of great importance. Our results support the possibility that the problem of finding an investment in stocks which exposes invested funds to a minimum level of risk is analogous to the problem of finding the magnetization of a random magnet. The interactions for this "random magnet problem" are given by the cross-correlation matrix C of stock returns. We find that random matrix theory allows us to make an estimate for C which outperforms the standard estimate in terms of constructing an investment which carries a minimum level of risk.

  11. Non-Hermitean Wishart random matrices (I)

    CERN Document Server

    Kanzieper, Eugene

    2010-01-01

    A non-Hermitean extension of paradigmatic Wishart random matrices is introduced to set up a theoretical framework for statistical analysis of (real, complex and real quaternion) stochastic time series representing two "remote" complex systems. The first paper in a series provides a detailed spectral theory of non-Hermitean Wishart random matrices composed of complex valued entries. The great emphasis is placed on an asymptotic analysis of the mean eigenvalue density for which we derive, among other results, a complex-plane analogue of the Marchenko-Pastur law. A surprising connection with a class of matrix models previously invented in the context of quantum chromodynamics is pointed out. This provides one more evidence of the ubiquity of Random Matrix Theory.

  12. Random Lasers for Broadband Directional Emission

    CERN Document Server

    Schönhuber, Sebastian; Hisch, Thomas; Deutsch, Christoph; Krall, Michael; Detz, Hermann; Strasser, Gottfried; Rotter, Stefan; Unterrainer, Karl

    2016-01-01

    Broadband coherent light sources are becoming increasingly important for sensing and spectroscopic applications, especially in the mid-infrared and terahertz (THz) spectral regions, where the unique absorption characteristics of a whole host of molecules are located. The desire to miniaturize such light emitters has recently lead to spectacular advances with compact on-chip lasers that cover both of these spectral regions. The long wavelength and the small size of the sources result in a strongly diverging laser beam that is difficult to focus on the target that one aims to perform spectroscopy with. Here, we introduce an unconventional solution to this vexing problem relying on a random laser to produce coherent broadband THz radiation as well as an almost diffraction limited far-field emission profile. Our random lasers do not require any fine-tuning and thus constitute a promising example of practical device applications for random lasing.

  13. Social patterns revealed through random matrix theory

    Science.gov (United States)

    Sarkar, Camellia; Jalan, Sarika

    2014-11-01

    Despite the tremendous advancements in the field of network theory, very few studies have taken weights in the interactions into consideration that emerge naturally in all real-world systems. Using random matrix analysis of a weighted social network, we demonstrate the profound impact of weights in interactions on emerging structural properties. The analysis reveals that randomness existing in particular time frame affects the decisions of individuals rendering them more freedom of choice in situations of financial security. While the structural organization of networks remains the same throughout all datasets, random matrix theory provides insight into the interaction pattern of individuals of the society in situations of crisis. It has also been contemplated that individual accountability in terms of weighted interactions remains as a key to success unless segregation of tasks comes into play.

  14. Universality of Correlations for Random Analytic Functions

    CERN Document Server

    Starr, Shannon

    2011-01-01

    We review a result obtained with Andrew Ledoan and Marco Merkli. Consider a random analytic function $f(z) = \\sum_{n=0}^{\\infty} a_n X_n z^n$, where the $X_n$'s are i.i.d., complex valued random variables with mean zero and unit variance, and the coefficients $a_n$ are non-random and chosen so that the variance transforms covariantly under conformal transformations of the domain. If the $X_n$'s are Gaussian, this is called a Gaussian analytic function (GAF). We prove that, even if the coefficients are not Gaussian, the zero set converges in distribution to that of a GAF near the boundary of the domain.

  15. Efficient broadcast on random geometric graphs

    Energy Technology Data Exchange (ETDEWEB)

    Bradonjic, Milan [Los Alamos National Laboratory; Elsasser, Robert [UNIV OF PADERBORN; Friedrich, Tobias [INTERNATIONAL COMPUTER SCI.; Sauerwald, Thomas [INTERNATIONAL COMPUTER SCI.

    2009-01-01

    A Randon Geometric Graph (RGG) is constructed by distributing n nodes uniformly at random in the unit square and connecting two nodes if their Euclidean distance is at most r, for some prescribed r. They analyze the following randomized broadcast algorithm on RGGs. At the beginning, there is only one informed node. Then in each round, each informed node chooses a neighbor uniformly at random and informs it. They prove that this algorithm informs every node in the largest component of a RGG in {Omicron}({radical}n/r) rounds with high probability. This holds for any value of r larger than the critical value for the emergence of a giant component. In particular, the result implies that the diameter of the giant component is {Theta}({radical}n/r).

  16. Random number generation from spontaneous Raman scattering

    Science.gov (United States)

    Collins, M. J.; Clark, A. S.; Xiong, C.; Mägi, E.; Steel, M. J.; Eggleton, B. J.

    2015-10-01

    We investigate the generation of random numbers via the quantum process of spontaneous Raman scattering. Spontaneous Raman photons are produced by illuminating a highly nonlinear chalcogenide glass ( As 2 S 3 ) fiber with a CW laser at a power well below the stimulated Raman threshold. Single Raman photons are collected and separated into two discrete wavelength detuning bins of equal scattering probability. The sequence of photon detection clicks is converted into a random bit stream. Postprocessing is applied to remove detector bias, resulting in a final bit rate of ˜650 kb/s. The collected random bit-sequences pass the NIST statistical test suite for one hundred 1 Mb samples, with the significance level set to α = 0.01 . The fiber is stable, robust and the high nonlinearity (compared to silica) allows for a short fiber length and low pump power favourable for real world application.

  17. Response of structures under random loading conditions

    International Nuclear Information System (INIS)

    In this paper the memory model concept is applied to study the response of structural beam components under randomly applied loads. Appropriate moment-curvature relationships are first developed from cyclic deformation tests on flexural sections deterministic loading conditions. These relationships are then applied by using memory model concept to predict the response of mild steel cantilever beams under random loading and the results are compared with experiments. Good agreement was obtained, the maximum difference between predicted and measured load being about 12 per cent. The lives of cantilever beams under random loading conditions are also predicted and the results agree well with experiment; the maximum and minimum ratios of predicted life over the experimental values were 95 per cent and 72 per cent respectively. (Auth.)

  18. Diffusion in randomly perturbed dissipative dynamics

    CERN Document Server

    Rodrigues, Christian S; de Moura, Alessandro P S; Grebogi, Celso; Klages, Rainer

    2014-01-01

    Dynamical systems having many coexisting attractors present interesting properties from both fundamental theoretical and modelling points of view. When such dynamics is under bounded random perturbations, the basins of attraction are no longer invariant and there is the possibility of transport among them. Here we introduce a basic theoretical setting which enables us to study this hopping process from the perspective of anomalous transport using the concept of a random dynamical system with holes. We apply it to a simple model by investigating the role of hyperbolicity for the transport among basins. We show numerically that our system exhibits non-Gaussian position distributions, power-law escape times, and subdiffusion. Our simulation results are reproduced consistently from stochastic Continuous Time Random Walk theory.

  19. Improving randomness characterization through Bayesian model selection

    CERN Document Server

    R., Rafael Díaz-H; Martínez, Alí M Angulo; U'Ren, Alfred B; Hirsch, Jorge G; Marsili, Matteo; Castillo, Isaac Pérez

    2016-01-01

    Nowadays random number generation plays an essential role in technology with important applications in areas ranging from cryptography, which lies at the core of current communication protocols, to Monte Carlo methods, and other probabilistic algorithms. In this context, a crucial scientific endeavour is to develop effective methods that allow the characterization of random number generators. However, commonly employed methods either lack formality (e.g. the NIST test suite), or are inapplicable in principle (e.g. the characterization derived from the Algorithmic Theory of Information (ATI)). In this letter we present a novel method based on Bayesian model selection, which is both rigorous and effective, for characterizing randomness in a bit sequence. We derive analytic expressions for a model's likelihood which is then used to compute its posterior probability distribution. Our method proves to be more rigorous than NIST's suite and the Borel-Normality criterion and its implementation is straightforward. We...

  20. Biased random walks on multiplex networks

    CERN Document Server

    Battiston, Federico; Latora, Vito

    2015-01-01

    Biased random walks on complex networks are a particular type of walks whose motion is biased on properties of the destination node, such as its degree. In recent years they have been exploited to design efficient strategies to explore a network, for instance by constructing maximally mixing trajectories or by sampling homogeneously the nodes. In multiplex networks, the nodes are related through different types of links (layers or communication channels), and the presence of connections at different layers multiplies the number of possible paths in the graph. In this work we introduce biased random walks on multiplex networks and provide analytical solutions for their long-term properties such as the stationary distribution and the entropy rate. We focus on degree-biased walks and distinguish between two subclasses of random walks: extensive biased walks consider the properties of each node separately at each layer, intensive biased walks deal instead with intrinsically multiplex variables. We study the effec...