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Sample records for 1-year-old erythrocebus patas

  1. Locomotor Anatomy and Behavior of Patas Monkeys (Erythrocebus patas with Comparison to Vervet Monkeys (Cercopithecus aethiops

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    Adrienne L. Zihlman

    2013-01-01

    Full Text Available Patas monkeys (Erythrocebus patas living in African savanna woodlands and grassland habitats have a locomotor system that allows them to run fast, presumably to avoid predators. Long fore- and hindlimbs, long foot bones, short toes, and a digitigrade foot posture were proposed as anatomical correlates with speed. In addition to skeletal proportions, soft tissue and whole body proportions are important components of the locomotor system. To further distinguish patas anatomy from other Old World monkeys, a comparative study based on dissection of skin, muscle, and bone from complete individuals of patas and vervet monkeys (Cercopithecus aethiops was undertaken. Analysis reveals that small adjustments in patas skeletal proportions, relative mass of limbs and tail, and specific muscle groups promote efficient sagittal limb motion. The ability to run fast is based on a locomotor system adapted for long distance walking. The patas’ larger home range and longer daily range than those of vervets give them access to highly dispersed, nutritious foods, water, and sleeping trees. Furthermore, patas monkeys have physiological adaptations that enable them to tolerate and dissipate heat. These features all contribute to the distinct adaptation that is the patas monkeys’ basis for survival in grassland and savanna woodland areas.

  2. Metabolism and pharmacokinetics of the combination Zidovudine plus Lamivudine in the adult Erythrocebus patas monkey determined by liquid chromatography-tandem mass spectrometric analysis

    International Nuclear Information System (INIS)

    Because of their similarity to humans, non-human primates constitute useful preclinical models in which to examine potential human drug toxicities. Antiretroviral nucleoside reverse transcriptase inhibitor (NRTI) toxicity is currently under investigation in Erythrocebus patas monkeys, and whereas NRTI pharmacokinetics have been studied in other monkey species, pharmacokinetics for Zidovudine plus Lamivudine (AZT/3TC) dosing have not been reported in the patas. Here we present 24 h serum pharmacokinetic parameters after a single oral exposure to the combination of AZT (40 mg) and 3TC (24 mg), doses equivalent to a human daily dose of Combivir (registered) . The patas (n = 3) AZT/3TC pharmacokinetic profiles were similar to those seen in other primate species. Average maximum serum concentrations (Cmax) for AZT and 3TC were 2.35 and 2.65 μg/ml, respectively, and were observed at 0.83 h (Tmax). Cmax was 13.34 μg/ml for the AZT-glucuronide (AZT-G) and was 0.023 μg/ml for the potentially toxic minor metabolite 3'-amino-3'-deoxythymidine (AMT), both occurring at about 1 h after dosing. Similar elimination half-times, 0.70 and 0.68 h-1, were found for AZT and AZT-G, respectively, while 3TC was eliminated about half as fast (0.33 h-1) resulting in AUC(0-∞) values of 6.97 μg/ml h for 3TC, 2.99 μg/ml h for AZT, 20.5 μg/ml h for AZT-G and 0.002 for AMT 6.97 μg/ml h. This study shows similar metabolism and pharmacokinetics for oral administration of AZT/3TC in the adult patas monkey, other primate species and humans. The data validate the use of the patas monkey for studies of NRTI toxicity

  3. Influence of environment enrichment to the behaviors of Erythrocebus patas in captive%环境丰容对赤猴行为分配影响的研究

    Institute of Scientific and Technical Information of China (English)

    陈霖; 叶安城; 池章伟

    2014-01-01

    In 2011, the 3 male and 3 female Erythrocebus patas raised in Fuzhou Zoo suffered from such unhealthy growing conditions as unitary behavior, coarse hairs, dry and ruptured tails and claudication, etc. They were transferred to a cage with certain environment enrichment and stayed for one year. Compared with the conditions in the previous cage, the allocations of Erythrocebus patas' day-time behaviors of foraging and sports increase by 61.3% and 213.2% respectively, and their walking and resting time decrease by 41.2% and 26.7% respectively. Now, the Erythrocebus patas have fine hairs, their tails recover to normal conditions, and claudication basically disappears.%2011年初福州动物园饲养的3公3雌赤猴出现行为单一、毛发粗糙、尾部干枯断裂、见有跛行等不良生长状况。为了改变猴群出现的不良状况,福州动物园将赤猴转移至新兽舍饲养,该新兽舍有较大的活动空间、良好的植被覆盖,还在新兽舍中安置有假山、攀网、跑道等设施供赤猴锻炼。此外,还将赤猴部分饲料由定点投喂改为抛洒投喂。经过约一年适应,赤猴昼间行为分配相较旧笼时觅食和运动行为分别提高61.3%、213.2%;行走和休息时间分别减少41.2%、26.7%,猴群被毛良好,尾部恢复正常,跛行现象基本消失。

  4. Emotional Development: 1 Year Olds

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    ... in Action Medical Editor & Editorial Advisory Board Sponsors Sponsorship Opporunities Spread the Word Shop AAP Find a Pediatrician ... & Stages > Toddler > Emotional Development: 1 Year Olds Ages & Stages Listen Español Text ...

  5. Social Development: 1 Year Olds

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    ... in Action Medical Editor & Editorial Advisory Board Sponsors Sponsorship Opporunities Spread the Word Shop AAP Find a Pediatrician ... Ages & Stages > Toddler > Social Development: 1 Year Olds Ages & Stages Listen Español Text ...

  6. Language Development: 1 Year Olds

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    ... Stages Listen Español Text Size Email Print Share Language Development: 1 Year Olds Page Content Article Body ... assured, it’s not your imagination. He’s developing his language and comprehension skills right on schedule. This giant ...

  7. Mitochondrial compromise in 3-year old patas monkeys exposed in utero to human-equivalent antiretroviral therapies.

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    Liu, Yongmin; Shim Park, Eunwoo; Gibbons, Alexander T; Shide, Eric D; Divi, Rao L; Woodward, Ruth A; Poirier, Miriam C

    2016-08-01

    Antiretroviral (ARV) drug therapy, given during pregnancy for prevention of mother-to-child transmission of human immunodeficiency virus 1 (HIV-1), induces fetal mitochondrial dysfunction in some children. However, the persistence/reversibility of that dysfunction is unclear. Here we have followed Erythrocebus patas (patas) monkey offspring for up to 3 years of age (similar in development to a 15-year old human) after exposure of the dams to human-equivalent in utero ARV exposure protocols. Pregnant patas dams (3-5/exposure group) were given ARV drug combinations that included zidovudine (AZT)/lamivudine (3TC)/abacavir (ABC), or AZT/3TC/nevirapine (NVP), for the last 10 weeks (50%) of gestation. Infants kept for 1 and 3 years also received drug for the first 6 weeks of life. In offpsring at birth, 1 and 3 years of age mitochondrial morphology, examined by electron microscopy (EM), was compromised compared to the unexposed controls. Mitochondrial DNA (mtDNA), measured by hybrid capture chemiluminescence assay (HCCA) was depleted in hearts of patas exposed to AZT/3TC/NVP at all ages (P year-old patas offspring was ∼50% reduced in AZT/3TC/ABC-exposed patas (P year-old patas sustain persistent mitochondrial dysfunction as a result of perinatal ARV drug exposure. Environ. Mol. Mutagen. 57:526-534, 2016. © 2016 Wiley Periodicals, Inc.

  8. Mitochondrial compromise in 3-year old patas monkeys exposed in utero to human-equivalent antiretroviral therapies.

    Science.gov (United States)

    Liu, Yongmin; Shim Park, Eunwoo; Gibbons, Alexander T; Shide, Eric D; Divi, Rao L; Woodward, Ruth A; Poirier, Miriam C

    2016-08-01

    Antiretroviral (ARV) drug therapy, given during pregnancy for prevention of mother-to-child transmission of human immunodeficiency virus 1 (HIV-1), induces fetal mitochondrial dysfunction in some children. However, the persistence/reversibility of that dysfunction is unclear. Here we have followed Erythrocebus patas (patas) monkey offspring for up to 3 years of age (similar in development to a 15-year old human) after exposure of the dams to human-equivalent in utero ARV exposure protocols. Pregnant patas dams (3-5/exposure group) were given ARV drug combinations that included zidovudine (AZT)/lamivudine (3TC)/abacavir (ABC), or AZT/3TC/nevirapine (NVP), for the last 10 weeks (50%) of gestation. Infants kept for 1 and 3 years also received drug for the first 6 weeks of life. In offpsring at birth, 1 and 3 years of age mitochondrial morphology, examined by electron microscopy (EM), was compromised compared to the unexposed controls. Mitochondrial DNA (mtDNA), measured by hybrid capture chemiluminescence assay (HCCA) was depleted in hearts of patas exposed to AZT/3TC/NVP at all ages (P < 0.05), but not in those exposed to AZT/3TC/ABC at any age. Compared to unexposed controls, mitochondrial reserve capacity oxygen consumption rate (OCR by Seahorse) in cultured bone marrow mesenchymal fibroblasts from 3-year-old patas offspring was ∼50% reduced in AZT/3TC/ABC-exposed patas (P < 0.01), but not in AZT/3TC/NVP-exposed patas. Overall the data show that 3-year-old patas sustain persistent mitochondrial dysfunction as a result of perinatal ARV drug exposure. Environ. Mol. Mutagen. 57:526-534, 2016. © 2016 Wiley Periodicals, Inc. PMID:27452341

  9. Parental spanking of 1-year-old children and subsequent child protective services involvement✩

    OpenAIRE

    Lee, Shawna J.; Grogan-Kaylor, Andrew; Berger, Lawrence M.

    2014-01-01

    The majority of U.S. parents spank their children, often beginning when their children are very young. We examined families (N=2,788) who participated in a longitudinal community-based study of new births in urban areas. Prospective analyses examined whether spanking by the child's mother, father, or mother's current partner when the child was 1-year-old was associated with household CPS involvement between age 1 and age 5. Results indicated that 30% of 1-year-olds were spanked at least once ...

  10. A rare case of peripheral T-cell lymphoma in 1-year-old child

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    Vignesh Kandakumar

    2011-01-01

    Full Text Available Peripheral T-cell lymphoma (PTCL represents approximately 12% of lymphoid neoplasms. They are even rarer in children and represent only 1% of Non-Hodgkin′s lymphoma in this age group. We report a case of PTCL in a 1-year-old female child for its rarity.

  11. A rare case of peripheral T-cell lymphoma in 1-year-old child

    OpenAIRE

    Vignesh Kandakumar; Prasanth Ganesan; Peush Bajpai; Rejiv Rajendranath; Sagar Tenali; Urmila Majhi; Ponni Sivaprakasam

    2011-01-01

    Peripheral T-cell lymphoma (PTCL) represents approximately 12% of lymphoid neoplasms. They are even rarer in children and represent only 1% of Non-Hodgkin′s lymphoma in this age group. We report a case of PTCL in a 1-year-old female child for its rarity.

  12. Parental spanking of 1-year-old children and subsequent child protective services involvement✩

    Science.gov (United States)

    Lee, Shawna J.; Grogan-Kaylor, Andrew; Berger, Lawrence M.

    2015-01-01

    The majority of U.S. parents spank their children, often beginning when their children are very young. We examined families (N=2,788) who participated in a longitudinal community-based study of new births in urban areas. Prospective analyses examined whether spanking by the child's mother, father, or mother's current partner when the child was 1-year-old was associated with household CPS involvement between age 1 and age 5. Results indicated that 30% of 1-year-olds were spanked at least once in the past month. Spanking at age 1 was associated with increased odds of subsequent CPS involvement (adjusted odds ratio=1.36, 95% CI [1.08, 1.71], ppunishment, professionals who work with families should counsel parents not to spank infants and toddlers. For optimal benefits, efforts to educate parents regarding alternative forms of discipline should begin during the child's first year of life. PMID:24602690

  13. Traumatic spinal epidural hematoma in a 1-year-old boy.

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    Tarbé de Saint Hardouin, A-L; Grévent, D; Sainte-Rose, C; Angoulvant, F; Chéron, G

    2016-07-01

    Traumatic spinal epidural hematoma is uncommon in children, making rapid diagnosis difficult. In this report, we present a case of traumatic cervical epidural hematoma in a 1-year-old boy, diagnosed with computed tomography scanning and magnetic resonance imaging (MRI). Management was conservative and the lesion regressed spontaneously. The presentation in childhood is often nonspecific. MRI is the imaging modality of choice for diagnosing these lesions. Conservative treatment has to be considered in cases with a benign clinical course and provided that the patient is followed up neurologically with repeated MRI. PMID:27266638

  14. Parental spanking of 1-year-old children and subsequent child protective services involvement.

    Science.gov (United States)

    Lee, Shawna J; Grogan-Kaylor, Andrew; Berger, Lawrence M

    2014-05-01

    The majority of U.S. parents spank their children, often beginning when their children are very young. We examined families (N=2,788) who participated in a longitudinal community-based study of new births in urban areas. Prospective analyses examined whether spanking by the child's mother, father, or mother's current partner when the child was 1-year-old was associated with household CPS involvement between age 1 and age 5. Results indicated that 30% of 1-year-olds were spanked at least once in the past month. Spanking at age 1 was associated with increased odds of subsequent CPS involvement (adjusted odds ratio=1.36, 95% CI [1.08, 1.71], pchildren, there was a 33% greater probability of subsequent CPS involvement for children who were spanked at age 1. Given the undesirable consequences of spanking children and a lack of empirical evidence to suggest positive effects of physical punishment, professionals who work with families should counsel parents not to spank infants and toddlers. For optimal benefits, efforts to educate parents regarding alternative forms of discipline should begin during the child's first year of life. PMID:24602690

  15. Evidence of Bordetella pertussis infection in vaccinated 1-year-old Danish children

    DEFF Research Database (Denmark)

    von Linstow, Marie-Louise; Pontoppidan, Peter Lotko; von König, Carl-Heinz Wirsing;

    2010-01-01

    We measured IgA and IgG antibodies to pertussis toxin (PT) and filamentous hemagglutinin (FHA) in sera from 203 1-year-old children who had received one to three doses of a monocomponent PT toxoid vaccine. Ten children (5%) had IgA antibody to PT indicating recent infection; seven of these children...... had received three doses of vaccine. PT IgA responders did not have significantly longer coughing episodes than PT IgA non-responders. Since an IgA antibody response occurs in only approximately 50% of infected children, the actual infection rate in our cohort is estimated to approximately 10......%. The apparent high Bordetella pertussis infection rate in Danish infants suggests that the monocomponent PT toxoid vaccine used in Denmark has limited efficacy against B. pertussis infection. A prospective immunization study comparing a multi-component vaccine with the present monocomponent PT toxoid vaccine...

  16. A 1-year-old boy with persistent, generalized eruption. Urticaria pigmentosa.

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    Mir, Adnan; Chamlin, Sarah L

    2014-01-01

    A healthy 1-year-old boy born at full term after an uncomplicated pregnancy presented to the dermatology clinic for a widespread eruption with gradual onset since 3 months of age. He was otherwise well, afebrile, feeding well, and gaining weight appropriately. The child was overall asymptomatic, though some of his lesions occasionally became red and pruritic. His mother noticed that after mild illnesses, he was more prone to these flares. She denied flushing, vomiting, diarrhea, respiratory distress, and irritability. He was meeting all developmental milestones and started walking at 11 months of age. The remainder of his review of systems was unremarkable, and family history was noncontributory. Physical exam revealed a well-appearing, well-nourished, playful, and interactive toddler. There were innumerable discrete and coalescing pink-brown macules and papules concentrated on the trunk and extending onto the proximal upper and lower extremities bilaterally, as well as the neck and lower face. Stroking the lesions quickly led to development of erythematous edematous wheals. There was no hepatosplenomegaly, and the lymph node exam was unremarkable.

  17. Development of 1-year-old computational phantom and calculation of organ doses during CT scans using Monte Carlo simulation

    International Nuclear Information System (INIS)

    With the rapidly growing number of CT examinations, the consequential radiation risk has aroused more and more attention. The average dose in each organ during CT scans can only be obtained by using Monte Carlo simulation with computational phantoms. Since children tend to have higher radiation sensitivity than adults, the radiation dose of pediatric CT examinations requires special attention and needs to be assessed accurately. So far, studies on organ doses from CT exposures for pediatric patients are still limited. In this work, a 1-year-old computational phantom was constructed. The body contour was obtained from the CT images of a 1-year-old physical phantom and the internal organs were deformed from an existing Chinese reference adult phantom. To ensure the organ locations in the 1-year-old computational phantom were consistent with those of the physical phantom, the organ locations in 1-year-old computational phantom were manually adjusted one by one, and the organ masses were adjusted to the corresponding Chinese reference values. Moreover, a CT scanner model was developed using the Monte Carlo technique and the 1-year-old computational phantom was applied to estimate organ doses derived from simulated CT exposures. As a result, a database including doses to 36 organs and tissues from 47 single axial scans was built. It has been verified by calculation that doses of axial scans are close to those of helical scans; therefore, this database could be applied to helical scans as well. Organ doses were calculated using the database and compared with those obtained from the measurements made in the physical phantom for helical scans. The differences between simulation and measurement were less than 25% for all organs. The result shows that the 1-year-old phantom developed in this work can be used to calculate organ doses in CT exposures, and the dose database provides a method for the estimation of 1-year-old patient doses in a variety of CT examinations. (paper)

  18. Development of 1-year-old computational phantom and calculation of organ doses during CT scans using Monte Carlo simulation.

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    Pan, Yuxi; Qiu, Rui; Gao, Linfeng; Ge, Chaoyong; Zheng, Junzheng; Xie, Wenzhang; Li, Junli

    2014-09-21

    With the rapidly growing number of CT examinations, the consequential radiation risk has aroused more and more attention. The average dose in each organ during CT scans can only be obtained by using Monte Carlo simulation with computational phantoms. Since children tend to have higher radiation sensitivity than adults, the radiation dose of pediatric CT examinations requires special attention and needs to be assessed accurately. So far, studies on organ doses from CT exposures for pediatric patients are still limited. In this work, a 1-year-old computational phantom was constructed. The body contour was obtained from the CT images of a 1-year-old physical phantom and the internal organs were deformed from an existing Chinese reference adult phantom. To ensure the organ locations in the 1-year-old computational phantom were consistent with those of the physical phantom, the organ locations in 1-year-old computational phantom were manually adjusted one by one, and the organ masses were adjusted to the corresponding Chinese reference values. Moreover, a CT scanner model was developed using the Monte Carlo technique and the 1-year-old computational phantom was applied to estimate organ doses derived from simulated CT exposures. As a result, a database including doses to 36 organs and tissues from 47 single axial scans was built. It has been verified by calculation that doses of axial scans are close to those of helical scans; therefore, this database could be applied to helical scans as well. Organ doses were calculated using the database and compared with those obtained from the measurements made in the physical phantom for helical scans. The differences between simulation and measurement were less than 25% for all organs. The result shows that the 1-year-old phantom developed in this work can be used to calculate organ doses in CT exposures, and the dose database provides a method for the estimation of 1-year-old patient doses in a variety of CT examinations.

  19. Two isoforms of cyclooxygenase contribute to augmented endothelium-dependent contractions in femoral arteries of 1-year-old rats

    Institute of Scientific and Technical Information of China (English)

    Yi SHI; Ricky YK MAN; Paul M VANHOUTTE

    2008-01-01

    Aim: The present experiments were designed to study the changes in endothe-lium-dependent contractions with aging. Methods: The rat femoral arteries of 20-week and 1-year-old rats with and without endothelium were suspended in organ chambers to record isometric tension. The production of oxygen-derived free radicals in the endothelium was measured with 2',7'-dichiorodihydrofluorescein diacetate (DCF) using confocal microscopy. Protein presences were determined by Western blotting. Results: In the arteries from the 1-year-old rats, endothe-lium-dependent relaxations to A23187 were reduced, but the endothelium-depen-dent contractions to A23187 (in the presence of Nω-nitro-L-arginine methyl ester hydrochloride [L-NAME; an inhibitor of nitric oxide synthase]) were augmented, demonstrating endothelial dysfunction with aging. Indomethacin normalized the responses, suggesting that a cyclooxygenase (COX)-dependent contraction is prominent in aging. The endothelium-dependent contractions were also prevented by terntroban (a blocker of thromboxane-prostanoid receptors), confirming the activation of thromboxane-prostanoid receptors on vascular smooth muscle. Valeryl salicylate and NS-398 (preferential inhibitors of COX-1 and COX-2, respectively) partially reduced the response, indicating that both COX-1 and COX-2 are involved. Western blotting confirmed the upregulation of both isoforms in the arteries of the 1-year-old rats. In the presence of L-NAME, A23187 increased the DCF fluores-cence in the endothelium, demonstrating that the production of oxygen-derived free radicals contributes to endothelium-dependent contractions. The activity of catalase was reduced in the arteries with endothelium of 1-year-old rats, indicating that hydrogen peroxide is the likely mediator of increased oxidative stress in the aging endothelium. Conclusion: Endothelium-dependent contractions are aug-mented with aging. Oxidative stress potentiates the response, and both COX-1 and COX-2 are

  20. Effect observation of 1-year-old child health%1岁儿童保健效果观察

    Institute of Scientific and Technical Information of China (English)

    李汉广

    2015-01-01

    Objective To explore effect of 1-year-old child health, and to improve participation rate of child health.Methods A total of 200 children at 1 year old in child health were divided into observation group (regular child health, 108 cases) and control group (irregular child health, 92 cases) by their participation frequency. Comparisons were made on nutritional status and physical development status between the two groups. Denver developmental screening test (DDST) was applied to evaluate their intelligent development situation. Results There was no statistically significant difference of stature and weight between the two groups (P>0.05). The observation group had higher hemoglobin level, lower bone alkaline phosphatase level and lower incidences of iron-deficiency anemia and rickets than the control group. The difference had statistical significance (P0.05);观察组血红蛋白水平高于对照组,骨碱性磷酸酶水平、缺铁性贫血及佝偻病发生率均低于对照组,差异有统计学意义(P<0.05);观察组儿童各项智能发育评分均高于对照组,差异有统计学意义(P<0.05)。结论积极参加儿童保健可促进儿童生长发育,应加强家长的儿童保健意识,以改善儿童保健状况。

  1. Diet in 1-year-old farm and control children and allergy development: results from the FARMFLORA birth cohort

    Science.gov (United States)

    Jonsson, Karin; Green, My; Barman, Malin; Sjöberg, Agneta; Brekke, Hilde K.; Wold, Agnes E.; Sandberg, Ann-Sofie

    2016-01-01

    Background A farming environment confers strong protection against allergy development. We have previously shown that farming mothers consume more full-fat dairy than control mothers, who instead consume more low-fat dairy, margarine, and oils; margarine and oil intake was associated with increased risk of allergy development in their children. Objectives The aims of this study were to investigate the differences in diet between children in farming and control families at 1 year of age, to investigate the relation between the diets of the mothers and their children, and to relate the children's diet to allergy development. Design The diet of 1-year-old children from dairy farming families (n=28) and from control families in the same rural area (n=37) was assessed by 24-h dietary recalls, followed by 24-h food diaries. Allergy was diagnosed by pediatricians at 3 years of age using strict predefined criteria. Results Farm children had a higher intake of farm milk, whole cream, cholesterol, saturated fat, and fat in total and tended to eat more butter, while controls consumed more carbohydrates and poultry and tended to eat more margarine. Farm children also had higher intakes of homemade porridge/gruel, oily fish, and iodine. The intake of butter and whole milk in children and mothers correlated significantly in farm families but not in controls. A weak negative association was found between seafood intake and allergy development, while allergy was positively associated with the intake of pork as well as zinc in the control group; these intakes also correlated with each other. Conclusions Consistent with mothers in farming families, the children consumed more full-fat dairy and saturated fat than did controls, but this could not be linked to the low risk of allergy in the farming group. Seafood intake might protect against allergy development, in accordance with earlier findings. PMID:27534847

  2. Diet in 1-year-old farm and control children and allergy development: results from the FARMFLORA birth cohort

    Directory of Open Access Journals (Sweden)

    Karin Jonsson

    2016-08-01

    Full Text Available Background: A farming environment confers strong protection against allergy development. We have previously shown that farming mothers consume more full-fat dairy than control mothers, who instead consume more low-fat dairy, margarine, and oils; margarine and oil intake was associated with increased risk of allergy development in their children. Objectives: The aims of this study were to investigate the differences in diet between children in farming and control families at 1 year of age, to investigate the relation between the diets of the mothers and their children, and to relate the children's diet to allergy development. Design: The diet of 1-year-old children from dairy farming families (n=28 and from control families in the same rural area (n=37 was assessed by 24-h dietary recalls, followed by 24-h food diaries. Allergy was diagnosed by pediatricians at 3 years of age using strict predefined criteria. Results: Farm children had a higher intake of farm milk, whole cream, cholesterol, saturated fat, and fat in total and tended to eat more butter, while controls consumed more carbohydrates and poultry and tended to eat more margarine. Farm children also had higher intakes of homemade porridge/gruel, oily fish, and iodine. The intake of butter and whole milk in children and mothers correlated significantly in farm families but not in controls. A weak negative association was found between seafood intake and allergy development, while allergy was positively associated with the intake of pork as well as zinc in the control group; these intakes also correlated with each other. Conclusions: Consistent with mothers in farming families, the children consumed more full-fat dairy and saturated fat than did controls, but this could not be linked to the low risk of allergy in the farming group. Seafood intake might protect against allergy development, in accordance with earlier findings.

  3. A congenital anterior urethral diverticulum associated with obstructive urinary symptoms in a 1-year-old male child: A case report and review of the literature

    Directory of Open Access Journals (Sweden)

    Mehmet Hanifi Okur

    2015-05-01

    Full Text Available Congenital anterior urethral diverticula are rarely found in children. We present the case of a 1-year-old male child with a congenital anterior urethral diverticulum. This condition can lead to obstructive lower urinary tract symptoms and urosepsis. The clinical presentation, diagnosis, and management of this rare condition are discussed in this report. The diagnosis was made using retrograde urethrography. Patient was treated with open diverticulectomy and urethroplasty

  4. Profound Vitamin B12 Deficiency in a 1-Year-Old Child in Botswana: A Call to Initiate Early Empiric Therapy.

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    Gajudhur, Juyotee; Slone, Jeremy S; Mehta, Parth S; Mahoney, Donald

    2016-08-01

    Vitamin B12 deficiency is a rare diagnosis in young children. We present the case of a 1-year-old Zimbabwean child with profound anemia. Further testing revealed undetectable levels of vitamin B12 and positive intrinsic factor antibodies that were drawn after the initiation of empiric treatment with parenteral vitamin B12. We report the evaluation and management of vitamin B12 deficiency in a resource-limited setting. Vitamin B12 deficiency should be considered in children presenting with unexplained cytopenias with consideration of empiric treatment with parenteral vitamin B12, as developmental and neurological complications of vitamin B12 deficiency can be devastating and permanent. PMID:27306229

  5. Perfil psicológico diferencial de las mujeres ludópatas: implicaciones para el tratamiento

    OpenAIRE

    Corral, Paz del; Echeburúa Odriozola, Enrique; Irureta, Mayalen

    2005-01-01

    En los últimos años ha habido un interés creciente por los aspectos psicopatológicos y terapéuticos de la ludopatía. Sin embargo, la mayor parte de las investigaciones han tenido como participantes a hombres ludópatas. Además, ha habido pocos estudios sobre las diferencias de género en la ludopatía, a pesar de que un tercio del total de ludópatas son mujeres. Los hombres manifiestan una preferencia por las máquinas recreativas, tienen frecuentemente un historial de abuso de alcohol o de condu...

  6. 0~1岁婴儿出生缺陷的流行病学调查%Epidemiological survey on 0-1 years old baby with birth defect

    Institute of Scientific and Technical Information of China (English)

    倪少义; 何洁壁; 陈少娜; 吴翔; 蔡幸生; 黄伟鹏; 王榕生; 洪艳苹; 倪少英; 卢晓航

    2012-01-01

    Objective To understand the incidence of birth defect in 0-1 years old baby in some regions of Jieyang, then to determine the focus groups for prevention. So that it can provide a foundation for birth defect prevention, pre-pregnancy and pregnancy care. Methods Those babies, who were born in Jiedong County, Puning City and Rongcheng District from March 3, 2011 to May 2, 2012 were surveyed by general investigation. Birth defect based on clinical diagnosis, its entity and statistical standard referred to the regulations of International Centre on Birth Defects and Prematurity. Results 238 cases of birth defect babies were found out of 10 773 cases of monitored new babies. The top five diseases of baby birth defects were congenital heart disease, talipes equinovarus, polydactyly, cleft lip and palate and fetal-edematous-syndrome. Some babies had higher incidence of birth defects, such as baby boy, low birth weight baby, and those babies whose mother did not take folic acid, vitamin and trace elements during pregnancy and whose family members smoking and excessive drinking (P < 0.05). Conclusion The incidence rate of birth defects in 0-1 years old baby is 220.92 per ten thousand in some regions of Jieyang City. It is slightly higher than the national average, so it needs attention from each side. Strengthening propaganda and education, screening and preventing birth defects are matters of great urgency.%目的 了解揭阳部分地区0~1岁婴儿出生缺陷的发病情况,确定预防的重点人群,为出生缺陷的预防和孕前、孕期保健提供依据.方法 采用普查的方式,对揭东县、普宁市、榕城区三地2011年3月3日~2012年5月2日出生的婴儿进行调查.出生缺陷以临床诊断为依据,病种及统计标准参照国际出生缺陷监测情报交换所的规定.结果 共监测10 773名婴儿,发现出生缺陷238例;婴儿出生缺陷排名前5位的疾病分别是先天性心脏病、马蹄内翻足、多指(趾)、唇(腭)裂

  7. Prediction function of early BMI increment to overweight of 1 year old infants%早期BMI增量对1岁婴幼儿超重的预测作用

    Institute of Scientific and Technical Information of China (English)

    乔永涛; 齐秀花; 张茜; 王明园; 刘杰

    2015-01-01

    Objective To analyze influencing factors of overweight and obesity in infancy.Methodsanalyze medical m anual of 533 infants in our hospital including height, weight, feeding history and anemia status.ResultsBMI value of 1 year o ld baby boys and girls showed statistical significance. Anemia is one of influence factors of overweight at age of 6 months and 9 months. Through logistics regression analysis, BMI increment of 0~3 months and 3-6 months is one of influence factors of over weight at 1 year old. ConclusionAnemia at age of 6 months and 9 months is one of influence factors of overweight or obesity , and growing fast is the risk factor for the overweight and obesity at early infancy.%目的:分析婴儿期超重及肥胖的影响因素。方法对在我院建立体检手册的533名婴儿的身高、体重、喂养史、是否存在贫血等进行分析。结果男婴与女婴在1岁时的BMI值具有统计学差异,在6个月或9个月时存在贫血是1岁时超重的影响因素,经logistics回归分析,0~3个月及3~6个月的BMI值增量是1岁时超重的影响因素。结论6个月或9个月患有贫血是婴幼儿超重及肥胖的危险因素,早期的快速增长是其危险因素。

  8. Superação da dormência em sementes de pata-de-vaca (Bauhinia angulata Vell. = Overcoming dormancy of pata-de-vaca (Bauhinia angulata Vell seeds.

    Directory of Open Access Journals (Sweden)

    Oscar José Smiderle

    2010-12-01

    Full Text Available O trabalho foi realizado no Laboratório de Análise de Sementes da Embrapa Roraima, com o objetivo de estudar métodos pré-germinativos em laboratório para a superação da dormência de sementes de pata-de-vaca. O delineamento experimental foi o inteiramente ao acaso com sete tratamentos e 4 repetições de 50 sementes. Os tratamentos pré-germinativos foram: escarificação com imersão em ácido sulfúrico (PA por 5, 10 e 15 minutos; imersão em álcool etílico por 5, 10 e 15 minutos; e testemunha, sem tratamento prévio nas sementes. As sementes foram incubadas a 25oC no interior de caixas plásticas, tipo ‘gerbox’, contendo como substrato papel ‘germitest’ umedecido. Diariamente, até 89 dias após a semeadura, foi feita avaliação da embebição e da germinação; a partir dos dados de germinação foi estimada a velocidade de germinação. Os resultados demonstraram que os tratamentos pré-germinativos promoveram acréscimo de pelo menos 50% na germinaçãodas sementes de pata-de-vaca, sendo que a escarificação com ácido sulfúrico (15 minutos, revelou ser o método mais efetivo para a superação da dormência desta espécie. A utilização de álcool (10 minutos pode ser uma boa alternativa para promover a germinação de sementes de pata-de-vaca.= - This study was carried out at Seed laboratory of Embrapa Roraima, with the objective to study the overcoming dormancy of pata-de-vaca (Bauhinia angulata seeds. The experimental design was a completely randomized design with seven treatments and four replicates of 50 seeds each. The pre-germinations treatments were: sulfuric acid - PA (5, 10 and 15 minutes, ethylene alcohol (5, 10 and 15 minutes, and control. The seeds were disposed in plastic boxes over humidified paper and incubated at 25oC in a germinator. The parameters evaluated were germination, imbibition, speed of germination, normal seedlings at 89 days after sowing. The germinated seeds were counted daily during 89

  9. Superação da dormência em sementes de pata-de-vaca (Bauhinia angulata Vell). = Overcoming dormancy of pata-de-vaca (Bauhinia angulata Vell) seeds.

    OpenAIRE

    Oscar José Smiderle; Francisco Joaci de Freitas Luz

    2010-01-01

    O trabalho foi realizado no Laboratório de Análise de Sementes da Embrapa Roraima, com o objetivo de estudar métodos pré-germinativos em laboratório para a superação da dormência de sementes de pata-de-vaca. O delineamento experimental foi o inteiramente ao acaso com sete tratamentos e 4 repetições de 50 sementes. Os tratamentos pré-germinativos foram: escarificação com imersão em ácido sulfúrico (PA) por 5, 10 e 15 minutos; imersão em álcool etílico por 5, 10 e 15 minutos; e testemunha, sem ...

  10. Avaliação da qualidade de amostras comerciais de boldo (Peumus boldus Molina, pata-de-vaca (Bauhinia spp. e ginco (Ginkgo biloba L. Control quality evaluation of commercial samples of boldo (Peumus boldus Molina, pata-de-vaca (Bauhinia spp. and ginkgo (Ginkgo biloba L.

    Directory of Open Access Journals (Sweden)

    J. G. de Melo

    2004-01-01

    Full Text Available O presente trabalho procurou avaliar a qualidade de produtos comercializados à base de boldo, pata-de-vaca e ginco, através dos parâmetros contidos na Farmacopéia Brasileira e na literatura específica. Foram analisadas oito amostras de boldo, nove de pata-de-vaca e sete de ginco, adquiridas em farmácias na cidade do Recife. A metodologia consistiu em avaliar: os rótulos e bulas dos produtos verificando se estavam de acordo com a RDC n o 17 de 24/02/2000 e a portaria 110/97 da ANVISA; realizar análise sensorial; verificar a autenticidade das amostras e sua pureza. Todas as embalagens de boldo, pata-de-vaca e seis de ginco continham erros ou ausência de informações científicas, além da falta de bula. Na verificação de impurezas, todas as de boldo, cinco de pata-de-vaca, e uma amostra de ginco foram reprovadas. Todos os produtos analisados apresentaram alguma irregularidade segundo os códigos oficiais, sendo necessário uma maior intensificação na vigilância de produtos à base de plantas medicinais no Brasil.This study aimed to evaluate the quality of commercial products prepared with boldo (Peumus boldus Molina, pata-de-vaca (Bauhinia spp. and ginkgo (Ginkgo biloba L. by using parameters from the Brazilian Pharmacopoeia and specific literature. Eight samples of "boldo", nine of "pata-de-vaca", and seven of ginkgo were analyzed, all bought from pharmacies in Recife (Pernambuco, Brazil. The methodology consisted in evaluating the products’ labels and instructions to verify their accordance to RDC n o 17 of 02/24/2000 and ANVISA (National Sanitary Surveillance Agency decree 110/97, undertaking a sensorial analysis, and verifying the authenticity and purity of the samples. All of the packages of "boldo" and "pata-de-vaca" and six of the packages of ginkgo contained mistakes or lacked scientific information; instructions were also missing. After analyzing for impurities, all samples of "boldo", five of "pata-de-vaca", and one of

  11. The Stain That Gets Increasingly Visible. The Ethnic Segregation in the Pata Rât (Stain snout Ghetto, Cluj-Napoca

    Directory of Open Access Journals (Sweden)

    Viorel Mionel

    2012-04-01

    Full Text Available This paper presents, in the first part, a brief theoretical analisys of the ethnic segregation and the causes entailing this kind of urban fragmentation. Undoubtedly, discrimination is one of the main reasons of segregation, closely followed by the countless social disadvantages. Besides all these, we may point out the poor quality of public policies which instead of improving the marginalized people’s situaion, pushes them deeper into poverty and stigma, as in the case study of Pata Rât, Cluj-Napoca. This paper aims at drawing attention to discrimination and segregation of the Gypsy people living in the outskirts of Cluj-Napoca city, usually called Pata Rât ghetto, and the urgent need for new inclusion policies.

  12. Reduced blood clearance and increased urinary excretion of N-nitrosodimethylamine in patas monkeys exposed to ethanol or isopropyl alcohol.

    Science.gov (United States)

    Anderson, L M; Koseniauskas, R; Burak, E S; Moskal, T J; Gombar, C T; Phillips, J M; Sansone, E B; Keimig, S; Magee, P N; Rice, J M

    1992-03-15

    Low concentrations of N-nitrosodimethylamine are metabolized in rodent and human liver by cytochrome P450IIE1, an activity competitively inhibitable by ethanol. In rodents coadministration of ethanol with N-nitrosodimethylamine results in increased tumorigenicity in extrahepatic organs, probably as a result of reduced hepatic clearance. To test this concept in a primate, the effects of ethanol cotreatment on the pharmacokinetics of N-nitrosodimethylamine were measured in male patas monkeys. Ethanol, 1.2 g/kg given p.o. before i.v. N-nitrosodimethylamine (1 mg/kg) or concurrently with an intragastric dose resulted in a 10-50-fold increase in the area under the blood concentration versus time curves and a 4-13-fold increase in mean residence times for N-nitrosodimethylamine. Isopropyl alcohol, 3.2 g/kg 24 h before N-nitrosodimethylamine, also increased these parameters 7-10-fold; this effect was associated with persistence of isopropyl alcohol and its metabolic product acetone, both IIE1 inhibitors, in the blood. While no N-nitrosodimethylamine was detected in expired air, trace amounts were found in urine. Ethanol and isopropyl alcohol pretreatment increased the maximum urinary N-nitrosodimethylamine concentration 15-50-fold and the percentage of the dose excreted in the urine by 100-800-fold. Thus ethanol and isopropyl alcohol greatly increase systemic exposure of extrahepatic organs to N-nitrosodimethylamine in a primate.

  13. Aprovechamiento de Patas de Pollos como Alternativa para disminuir Residuos Generados en los Mataderos Use of Chicken Feet as an Alternative to the reduce Wastes from Slaughterhouse

    Directory of Open Access Journals (Sweden)

    Poliana F Almeida

    2012-01-01

    Full Text Available Se presenta un estudio sobre la producción de jaleas y gelatinas a partir de las patas de pollo, usualmente producidas como desechos de los mataderos de aves. La investigación se llevó a cabo en dos etapas. En la primera etapa, las jaleas se obtuvieron a partir de las patas del pollo y se evaluaron sus cualidades sensoriales para verificar su aceptabilidad. En la segunda etapa, se produjo gelatinas y se analizó también sus cualidades sensoriales para comprobar su aceptabilidad. Los resultados mostraron que la mayoría de los catadores aprobaron los productos con más de 7 puntos en la escala hedónica y más del 80% dijeron que consumirían los productos. Los niveles de proteínas en las jaleas y gelatinas de patas de pollo superaron en cuatro veces los niveles de los productos comerciales, lo que indica una superioridad con respecto a las calidades químicas y potencialmente medicinales.A study on the production of jelly and gelatin from chicken feet, produced as wasted from chicken slaughterhouse is presented. The study was conducted in two parts. In the first part, jellies were produced from chicken feet and sensory quality was done to verify their acceptability. In the second step, gelatins were elaborated from chicken feet and also subjected to sensory analysis. Results showed that most experts in the panel accepted the products with more than 7 points in the hedonic scale and 80% said that they would consume these chicken products. Gelatin and jelly protein contents were four times larger than commercial products, indicating superiority in their chemistry and potential medicinal qualities.

  14. Determination of normal reference ranges for venous blood count among 526 children aging from 1year old to 12 years old in Shanghai%上海市526例1~12岁儿童静脉血血常规正常参考区间建立

    Institute of Scientific and Technical Information of China (English)

    高原; 邹琛; 蒋婕; 杨剑敏; 田先敏

    2015-01-01

    Objective To determine normal reference ranges for venous blood count among children aging from 1 year old to 12 years old.Methods These normal reference ranges were defined in a population of 526 healthy children who had no blood system diseases,allergic diseases,respiratory system diseases,urinary system diseases,digestive system disease,rheumatoid disease,thyroid disease,parasitic infections,malignancies and genetic disease,etc.Values of white blood cell count (WBC),red blood cell count (RBC),hemoglobin (Hb)concentration,red blood cell specific volume (Hct),mean corpusular volume(MCV),mean cell hemoglo-bin (MCH),mean corpuscular hemoglobin(MCHC),platelet (PLT),percentage of neutrophil (NE%),percentage of lymphocyte (LY%),percentage of mononuclear cells (MO%),percentage of acidophilic granulocyte (EOS%).Statistical analysis was done on various parameters that we recorded,and then for every parameter,we could get the various reference ranges for different age groups.Results The subjects were divided into 4 groups based on age.Besides the parameters of WBC count and classification of WBC,the rest of parameters were proved to be of no statistical difference between 4 groups..After an integration of the values,we could get the results as follows:RBC(4.02-5.2)×10 1 2/L,HGB 108-144 g/L,Hct 35.2%-40.4%,MCV 74.6-89.9 fL,MCH 20.9-34.7 pg,MCHC 332- 340 g/L,PLT(157 - 409 )× 10 9/L.WBC count did not have statistical difference between the age group 6-0.05),合并后得到 RBC:(4.02~5.2)×1012/L,HGB:108~144 g/L, Hct:35.2%~40.4%,MCV:74.6~89.9 fL,MCH:20.9~34.7 pg,MCHC:332~340 g/L,PLT:(157~409)×109/L。WBC 除6~0.05),其余各组间差异有统计学意义(P <0.05),经合并后得到1~<3岁组:(4.88~13.38)×109/L,3~<6岁组:(4.26~11.6)×109/L,6~12岁组:(4.24~10.24)×109/L。WBC 分类结果在不同年龄段差异有统计学意义(P <0.05),1~岁 NE:29%~32%,LY:58%~61%;3~<6岁组 NE:43%~46%,LY:43%~46%;6~<9岁组 NE:49%~52%,LY:38%~40%;9

  15. pata Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  16. Synthesis of Biotin Linkers with the Activated Triple Bond Donor [p-(N-propynoylaminotoluic Acid] (PATA for Efficient Biotinylation of Peptides and Oligonucleotides

    Directory of Open Access Journals (Sweden)

    Martina Jezowska

    2012-11-01

    Full Text Available Biotin is an important molecule for modern biological studies including, e.g., cellular transport. Its exclusive affinity to fluorescent streptavidin/avidin proteins allows ready and specific detection. As a consequence methods for the attachment of biotin to various biological targets are of high importance, especially when they are very selective and can also proceed in water. One useful method is Hüisgen dipolar [3+2]-cycloaddition, commonly referred to as “click chemistry”. As we reported recently, the activated triple bond donor p-(N-propynoylaminotoluic acid (PATA gives excellent results when used for conjugations at submicromolar concentrations. Thus, we have designed and synthesized two biotin linkers, with different lengths equipped with this activated triple bond donor and we proceeded with biotinylation of oligonucleotides and C-myc peptide both in solution and on solid support with excellent yields of conversion.

  17. Metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in the patas monkey: pharmacokinetics and characterization of glucuronide metabolites.

    Science.gov (United States)

    Hecht, S S; Trushin, N; Reid-Quinn, C A; Burak, E S; Jones, A B; Southers, J L; Gombar, C T; Carmella, S G; Anderson, L M; Rice, J M

    1993-02-01

    The metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) was examined in the patas monkey, in order to provide further information about NNK metabolic pathways in primates. Female patas monkeys were given i.v. injections of [5-3H]NNK, and metabolites in serum and urine were analyzed by HPLC. Metabolism by alpha-hydroxylation of NNK was rapid and extensive, and the products of this pathway, 4-hydroxy-4-(3-pyridyl)butyric acid and 4-oxo-4-(3-pyridyl) butyric acid, accounted for a relatively large proportion of serum and urinary metabolites at all time points. This is significant because the formation of these products is associated with modification of DNA by NNK. The other major metabolic pathway was carbonyl reduction to 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), which detected both unconjugated and diastereomeric O-glucuronides. One of these glucuronides had been previously identified in rat urine, but the other diastereomer, which was the more prevalent of the two in serum and urine, had not been observed in studies of NNK metabolism in rodents. It was characterized by its spectral properties, by enzymatic hydrolysis to NNAL, and by derivatization of the released NNAL enantiomer with (R)-(+)-alpha-methylbenzylisocyanate. The two NNAL glucuronides accounted for 15-20% of the urinary metabolites in monkeys given 0.1 micrograms/kg NNK, which is similar to a smoker's dose, suggesting their use as dosimeters of NNK exposure in humans. Pharmacokinetic parameters were consistent with those observed in previous studies of nitrosamines, and varied predictably with body weight of five species. The results of this study have provided new insights relevant to assessing human metabolism of NNK.

  18. Psicopatología, crimen violento, cine y realidad: desmontando mitos sobre psicópatas y psicóticos

    Directory of Open Access Journals (Sweden)

    José Manuel Pozueco Romero

    2015-08-01

    Full Text Available Psicosis, esquizofrenia, paranoia, personalidad múltiple y otro sinfín de términos son los que parecen coincidir con los conceptos coloquiales y peyorativos de locos, tarados, etc. Según numerosos autores, parece ser que la psicosis es la enfermedad mental más grave que existe, y, también, es evidente la cantidad de veces que ha sido (mal utilizada para recrear centenares de películas; el ejemplo más claro de esto mismo lo tenemos en el famoso film de Alfred Hitchcock, Psicosis, que analizamos aquí desde una perspectiva psicológico-forense y criminológica. Por otra parte, el tópico de la psicopatía también ha venido siendo amplia y erróneamente abordado por los medios de comunicación, y mal caracterizado en numerosas películas y series televisivas, todo esto a pesar de que hoy día se trata de un constructo clínico-forense válido y fiable. La relación de la psicopatía con la violencia y la criminalidad es bastante conocida, si bien este aspecto también requiere de una serie de rigurosos matices. En este artículo trataremos de desmontar el mito generalizado de que los enfermos mentales son muy peligrosos, y de que su criminalidad se ciñe exclusivamente a los homicidios, algo que también extienden muchos autores al caso de los psicópatas.

  19. Efeitos do alfa-tocoferol nas lesões de isquemia-reperfusão induzidas em pata direita de ratos

    Directory of Open Access Journals (Sweden)

    Bitu-Moreno José

    2001-01-01

    Full Text Available Recentes estudos demonstraram que os radicais livres de oxigênio parecem desempenhar papel importante nas lesões de isquemia-reperfusão. O alfa-tocoferol(AT age in vivo como um anti-oxidante. Nosso objetivo foi o de verificar se o AT atenuava as lesões de isquemia-reperfusão em pata direita de ratos. Os animais, randomizados, foram divididos nos seguintes grupos(G: G1-controle sem isquemia; G2 e G3 - quatro horas isquemia e duas reperfusão. Os animais do G2 foram tratados com salina e os do G3 com AT, 50mg/kg. Como parâmetros examinamos as alterações de volume e circunferência do pé direito ao longo do experimento, assim como a captação de 99mTc-pirofosfato e a microscopia eletrônica de transmissão do músculo soleus direito. Os aumentos de volume e circunferência do pé dos animais do G2 foram estatisticamente maiores quando comparados com o G1. As medidas do G3 não diferiram do G1. A captação de 99mTc-pirofosfato foi bem aumentada nos G2 e G3, quando comparados ao G1, porém sem diferenças entre os grupos isquêmicos. As lesões ao MET foram menos intensas em três animais do G3, quando comparados ao G2. Conclusão: O tratamento com AT diminuiu a formação do edema mas só protegeu parcialmente as células musculares contra as lesões de isquemia-reperfusão.

  20. Evidence of Bordetella pertussis infection in vaccinated 1-year-old Danish children

    DEFF Research Database (Denmark)

    von Linstow, Marie-Louise; Pontoppidan, Peter Lotko; von König, Carl-Heinz Wirsing;

    2010-01-01

    %. The apparent high Bordetella pertussis infection rate in Danish infants suggests that the monocomponent PT toxoid vaccine used in Denmark has limited efficacy against B. pertussis infection. A prospective immunization study comparing a multi-component vaccine with the present monocomponent PT toxoid vaccine...

  1. Artificial grammar learning by 1-year-olds leads to specific and abstract knowledge.

    Science.gov (United States)

    Gomez, R L; Gerken, L

    1999-03-01

    Four experiments used the head-turn preference procedure to assess whether infants could extract and remember information from auditory strings produced by a miniature artificial grammar. In all four experiments, infants generalized to new structure by discriminating new grammatical strings from ungrammatical ones after less than 2 min exposure to the grammar. Infants acquired specific information about the grammar as demonstrated by the ability to discriminate new grammatical strings from those with illegal endpoints (Experiment 1). Infants also discriminated new grammatical strings from those with string-internal pairwise violations (Experiments 2 and 3). Infants in Experiment 4 abstracted beyond specific word order as demonstrated by the ability to discriminate new strings produced by their training grammar from strings produced by another grammar despite a change in vocabulary between training and test. We discuss the implications of these findings for the study of language acquisition.

  2. PREDICTORS OF EMOTIONAL AND BEHAVIORAL PROBLEMS IN 1-YEAR-OLD CHILDREN: A LONGITUDINAL PERSPECTIVE.

    Science.gov (United States)

    Sirvinskiene, Giedre; Zemaitiene, Nida; Jusiene, Roma; Markuniene, Egle

    2016-07-01

    Emotional and behavioral problems at an early age can reasonably be considered a high-risk factor for later mental health disorders. The aim of the article is to reveal predictive factors of 1½-year-old children's emotional and behavioral problems. The study was a part of a prospective birth-cohort study. The study sample consisted of 172 full-term infants (born during Gestational Weeks 37-42) and their mothers. Emotional and behavioral problems at the age of 1½ years were measured using the Child Behavior Checklist for Ages 1½-5 (T. Achenbach & L. Rescorla, 2000), which was completed by mothers. Emotional and behavioral problems at age of 1½ years were more prevalent in infants born via cesarean section, as compared to infants born vaginally without administration of medication. Newborns' suboptimal functioning after birth, complicated emotional acceptance of pregnancy, a couple's nonsatisfactory relationship during pregnancy, maternal distress during pregnancy and in the first months after childbirth, and inflexible and parent-oriented attitudes toward infant-rearing also predicted children's emotional and behavioral problems independent of sociodemographic factors. Results suggest that biomedical and psychosocial factors which manifest themselves in the prenatal and perinatal periods can have associations with later infant and child mental health. PMID:27336695

  3. Nutrition and Iron Status of 1-Year Olds following a Revision in Infant Dietary Recommendations

    OpenAIRE

    Thorisdottir, Asa V.; Inga Thorsdottir; Gestur I. Palsson

    2011-01-01

    A previous study showed low iron status in 12-month-old Icelandic infants associated most strongly with cow's milk intake and growth. Infant dietary recommendations were revised in 2003. This study investigated nutrition and iron status in a new infant cohort. Subjects/Methods. Randomly selected infants were prospectively investigated for diet, anthropometry, and iron status (n = 110–141). Results. Breastfeeding initiation rate was 98%; 38% of 5-month olds were exclusively and 20% of 12-month...

  4. Serological Evidence of Infection with Endemic Human Pathogens Among Free-Ranging Old World Monkeys in Puerto Rico.

    Science.gov (United States)

    Hemme, Ryan R; Lopez-Ortiz, Ricardo; Garcia, Brenda Rivera; Sharp, Tyler M; Galloway, Renee L; Elrod, Mindy G; Hunsperger, Elizabeth A

    2016-05-01

    Serum specimens from free-ranging but nonnative patas monkeys (Erythrocebus patas) and rhesus macaques (Macaca mulatta) in southwestern Puerto Rico (PR) were tested for antibodies to infection with dengue viruses (DENVs), West Nile virus (WNV), Leptospira species, and Burkholderia pseudomallei by microneutralization, plaque reduction neutralization, microscopic agglutination, and indirect hemagglutination, respectively. Of 23 animals (21 E. patas and two M. mulatta) tested, all had evidence of prior DENV infection, and of 17 animals tested for WNV, nine (53%) had evidence of prior infection. Of 24 (22 E. patas, two M. mulatta) tested for Leptospira spp., 10 (42%) had evidence of prior exposure, and one patas monkey had antibodies against B. pseudomallei The acquisition of pathogens endemic among humans in PR by resident nonhuman primates merits further study to define modes of acquisition. PMID:27001754

  5. Unexpected dominance of 1 year old parr among migrating salmon and sea trout individuals in the River Siesartis, Lithuania

    Directory of Open Access Journals (Sweden)

    Kęstutis Skrupskelis

    2015-12-01

    However, 1 year age parr unexpectedly dominated among salmon juveniles descending towards the Sea in the restocked Siesartis River, which is situated 400 km to the Baltic Sea. The same phenomenon has been observed among migrating sea trout individuals, too. Mass migration of 1 year age salmon and sea trout parr with mean body length ranging from 69 to 150 mm can hardly be explained by density-dependant regulatory mechanisms alone. Possible impact of particularly long distance migration route is also discussed.

  6. Individual variation in fathers' testosterone reactivity to infant distress predicts parenting behaviors with their 1-year-old infants.

    Science.gov (United States)

    Kuo, Patty X; Saini, Ekjyot K; Thomason, Elizabeth; Schultheiss, Oliver C; Gonzalez, Richard; Volling, Brenda L

    2016-04-01

    Positive father involvement is associated with positive child outcomes. There is great variation in fathers' involvement and fathering behaviors, and men's testosterone (T) has been proposed as a potential biological contributor to paternal involvement. Previous studies investigating testosterone changes in response to father-infant interactions or exposure to infant cues were unclear as to whether individual variation in T is predictive of fathering behavior. We show that individual variation in fathers' T reactivity to their infants during a challenging laboratory paradigm (Strange Situation) uniquely predicted fathers' positive parenting behaviors during a subsequent father-infant interaction, in addition to other psychosocial determinants of paternal involvement, such as dispositional empathy and marital quality. The findings have implications for understanding fathering behaviors and how fathers can contribute to their children's socioemotional development. © 2015 Wiley Periodicals, Inc. Dev Psychobiol 58: 303-314, 2016. PMID:26497119

  7. Expression and inducibility of cytochrome P450 isoforms in 1-year-old intrasplenic liver cell transplants in rats.

    Science.gov (United States)

    Lupp, Amelie; Danz, Manfred; Müller, Dieter; Klinger, Wolfgang

    2002-03-01

    Syngenic fetal liver tissue suspensions were transplanted into the spleens of 60- to 90-day-old male Fischer 344 inbred rats. Transplant recipients were compared with age-matched control rats. One year after surgery, the animals were treated orally with beta-naphthoflavone (BNF), phenobarbital (PB), dexamethasone (DEX) or the respective solvents 24 or 48 h before being killed. Expression of cytochrome P450 (P450) isoforms in spleens and orthotopic livers was assessed by immunohistochemistry and P450-dependent monooxygenase functions by the model reactions ethoxyresorufin O-deethylation (EROD), ethoxycoumarin O-deethylation (ECOD), pentoxyresorufin O-depentylation (PROD) and ethylmorphine N-demethylation (EMND). Spleens of control animals displayed almost no expression of P450 isoforms and P450-mediated monooxygenase functions. Similar to liver, in the transplanted hepatocytes no P450 1A1 but distinct P450 2B1 and 3A2 expression was observed. Furthermore, the transplant-containing spleens displayed significant EROD, ECOD, PROD and EMND activities. Similar to normal liver, BNF treatment enhanced P450 1A1 and 2B1, PB induced P450 2B1 and 3A2, and DEX induced P450 3A2 expression in the transplanted hepatocytes. Correspondingly, in the transplant-containing spleens EROD, ECOD and PROD activities were significantly enhanced following BNF treatment, EROD, ECOD, PROD and EMND activities after PB administration, and EMND activity by DEX treatment. These results demonstrate that hepatocytes originating from fetal liver tissue suspensions can survive in the spleen at least for 1 year. They have differentiated into adult hepatocytes and even 1 year after transplantation express different P450 isoforms which are inducible by BNF, PB and DEX, corresponding to normal adult liver.

  8. External Sources of Individual Differences? A Cross-Linguistic Analysis of the Phonetics of Mothers' Speech to 1-Year-Old Children.

    Science.gov (United States)

    Vihman, Marilyn M.; And Others

    1994-01-01

    Sampled the speech of American, French, and Swedish mothers to their one-year olds, to analyze distribution of phonetic parameters of adult speech, as well as children's own early words. Found that variability is greater in child words than in adult speech, and mother-child dyads showed no evidence of specific maternal influence on phonetics of…

  9. Adaptação cultural de instrumento para avaliação da capacidade física em cardiopatas Adaptación cultural de instrumento para evaluación de la capacidad física en cardiópatas Cultural adaptation of an instrument to assess physical fitness in cardiac patients

    Directory of Open Access Journals (Sweden)

    Gabriela de Barros Leite Domingues

    2011-04-01

    Full Text Available OBJETIVO: Validar o conteúdo e avaliar a confiabilidade do instrumento Veterans Specific Activity Questionnaire, adaptado culturalmente para uso na população brasileira de cardiopatas. MÉTODOS: O instrumento foi traduzido, retrotraduzido e analisado por comitê de juízes para avaliação das equivalências semântico-idiomática e cultural. As atividades físicas indicadas no instrumento incomuns ao cotidiano da população-alvo foram substituídas. Outro comitê de especialistas analisou a equivalência metabólica das atividades substituídas. A proporção de concordância de avaliação dos juízes foi quantificada pelo Índice de Validade de Conteúdo. O pré-teste foi realizado em duas etapas (n1 e n2 = 15. A confiabilidade foi avaliada por meio do teste re-teste (intervalo de 7-15 dias, n = 50. RESULTADOS: Na avaliação das equivalências semântico-idiomática e cultural, os itens com Índice de Validade de Conteúdo OBJETIVO: Validar el contenido y la confiabilidad del instrumento Veterans Specific Activity Questionnaire, adaptado culturalmente para uso en la población brasileña de cardiópatas. MÉTODOS: El instrumento fue traducido y retro traducido y analizado por comité de árbitros para evaluación de las equivalencias semántico-idiomática y cultural. Las actividades físicas indicadas en el instrumento, no comunes a lo cotidiano de la población de interés fueron sustituidas. Otro comité de especialistas analizó la equivalencia metabólica de las actividades sustituidas. La proporción de concordancia de evaluación de los árbitros fue cuantificada por el Índice de Validez de Contenido. La pre-test fue realizada en dos etapas (n1 y n2=15. La confiabilidad fue evaluada por medio de la prueba re-test (intervalo de 7-15 días, n=50. RESULTADOS: En la evaluación de las equivalencias semántico-idiomática y cultural, los itens con Índice de Validez de Contenido OBJECTIVE: To validate the content and to evaluate the

  10. Doença coronária obstrutiva em hepatopatas crônicos que aguardam transplante hepático Enfermedad coronaria obstructiva en hepatópatas crónicos que aguardan trasplante hepático Obstructive coronary disease in patients with chronic liver disease awaiting liver transplantation

    Directory of Open Access Journals (Sweden)

    Moacir Fernandes de Godoy

    2011-01-01

    grado importante con consecuente aumento de riesgo o incluso contraindicación para trasplante hepático. OBJETIVOS: Analizar la contribución de los factores de riesgo clásicos para la enfermedad arterial coronaria (EAC en pacientes portadores de IHA con y sin coronariopatía obstructiva. MÉTODOS: Evaluación de los factores de riesgo para EAC en 119 pacientes, en un servicio de referencia para trasplante hepático, con las siguientes características: más de 40 años de edad, portadores de IHA y sometidos a cinecoronariografía. RESULTADOS: Coronariopatía obstructiva fue detectada en 21 (17,6% de los casos. Estos pacientes presentaban realmente niveles bajos de colesterol, siendo de 129,0±53,5mg/dL con mediana de 117,0mg/dL en los hepatópatas con coronarias normales y 135,4±51,7mg/dL con mediana de 122,0mg/dL en los hepatópatas con coronariopatía obstructiva (P=0,8215. En la regresión logística multivariada, la edad, el sexo, el índice de masa corporal, así como las presencias de diabetes, de tabaquismo y de etilismo no tuvieron significancia estadística aislada en la diferenciación entre los grupos. También no hubo asociación con la etiología de la IHA. A su vez, la hipertensión arterial se mostró relevante en la asociación con EAC (P=0,0474. CONCLUSIÓN: Sólo la hipertensión arterial fue factor de riesgo con significancia estadística para el desarrollo de EAC en pacientes con IHA aguardando trasplante hepático. Por ser un factor de riesgo cambiable, este hallazgo orienta hacia una práctica de actitudes terapéuticas en la tentativa de evitarse o retardar el desarrollo de la EAC en estos pacientes.BACKGROUND: Advanced liver failure (ALF usually presents hypocholesterolemia. Nevertheless, some patients with ALF develops major coronary obstructive diseases with consequent increased risk or contraindication to liver transplantation. OBJECTIVE: To analyze the contribution of classical risk factors for coronary artery disease (CAD in patients

  11. Allelopathic activity of fresh and dry extracts of Stryphnodendron adstringens (Mart. Coville and Bauhinia forficata link leaves on the germination and initial development of tomato seedlings / Atividade alelopática dos extratos fresco e seco de folhas de barbatimão (Stryphnodendron adstringens (Mart. Coville e pata-devaca (Bauhinia forficata link sobre a germinação e desenvolvimento inicial de plântulas de tomate

    Directory of Open Access Journals (Sweden)

    Gisela Ferreira

    2009-07-01

    Full Text Available The objective of this study aimed at the verification of the allelopatic action of extracts of “pata-devaca” (Bauhinia forficata Link and “barbatimão” (Stryphnodendron adstringens (Mart. Coville on seeds of tomato (Lycopersicum esculentum Mill. Tomato seeds placed in translucent “gerbox” were treated with aqueous extracts prepared with fresh and dry leaves of the tested species at the following concentrations: 100%, 75%, 50%, 25%, and 0% (control. The experimental design was completely randomized with five treatments and five replications of 25 seeds per plot per species. The data were submitted to the analysis of variance and the means compared by Tukey test at 5% of probability. Germination percentage, mean time and germination rates (MGT and MGR, and mean of the primary root length were evaluated. No difference was found for germination percentage of tomato seeds for the different extracts. For MGR, all treatments with fresh leaf extract differed from the check. MGT and MGR showed differences among the following dry leaf extracts concentrations: 25%, 75% and 100%. All treatments presented inhibitory effect on the length of the primary root.O trabalho teve por objetivo verificar a ação alelopática de pata-de-vaca (Bauhinia forficata Link, e barbatimão (Stryphnodendron adstringens (Mart. Coville em sementes de tomate (Lycopersicum esculentum Mill. As sementes de tomate foram tratadas com extratos aquosos preparados a partir de folhas frescas e secas das espécies-teste nas concentrações de 100%, 75%, 50%, 25% e 0% (controle e acondicionadas em ‘gerbox’ transparente. O delineamento experimental foi inteiramente casualizado, com cinco tratamentos e cinco repetições de 25 sementes por parcela por espécie-teste. Foram avaliados porcentagem, tempo e velocidade médios de germinação e, comprimento médio de raiz primária. Os dados foram submetidos à análise de variância e as médias comparadas por Tukey a 5% de

  12. Do deposed adult male Sichuan snub-nosed monkeys Rhinopithecus roxellana roam as solitary bachelors or continue to interact with former band members?

    Institute of Scientific and Technical Information of China (English)

    Dapeng ZHAO; Baoguo LI

    2009-01-01

    @@ Dispersal pattems exhibited by group-living animals play an important role in individual reproductive success and survival, as well as population and social dynamics (Greenwood, 1980; Isbell and van Vuren, 1996; Kappeler and van Schaik, 2002). Dispersing individuals may emigrate voluntarily, or they may be forcibly evicted by other individuals (Pusey and Packer, 1987; Clobert et al., 2001). One cause of individual dispersal is when an extra-group male compels another male to leave a group of females. This phenomenon has been well documented in primates, especially Old World monkey species (e.g. Colobus vellerosus: Saj and Sicotte, 2005; Erythrocebus patas: Ohsawa, 2003; Macaca fascicularis: van Noordwijk and van Schaik, 2001).

  13. Hábitos alimentares de crianças menores de 1 ano amamentadas e não-amamentadas Feeding habits of breastfed and non-breastfed children up to 1 year old

    Directory of Open Access Journals (Sweden)

    Graciete O. Vieira

    2004-01-01

    Full Text Available OBJETIVOS: Descrever os hábitos alimentares de crianças amamentadas e não-amamentadas através da análise dos alimentos consumidos pelas crianças menores de 1 ano de idade na cidade de Feira de Santana, BA, no ano de 2001. MÉTODOS: Foi realizado um estudo transversal, no qual foram aplicados questionários às mães das crianças menores de 1 ano no dia nacional de vacinação, presentes nas 44 (71% unidades de vacinação, selecionadas por estratificação simples. Foram avaliadas 2.319 crianças, representando 24,3% da população estimada. As medidas de associação calculadas foram: razão de prevalência, com intervalo de confiança a 95%, e de significância estatística, através do teste do qui-quadrado com respectivo valor p. RESULTADOS: Nas crianças com idade igual ou inferior a 4 meses e não-amamentadas, foi observada uma chance 8,2 e 6,7 vezes maior de a criança ser alimentada, respectivamente, com a refeição da família (IC 95% 3,23-20,66 e com papas de legumes (IC 95% 3,84-11,78. Na mesma faixa etária, as prevalências de crianças não-amamentadas que receberam água, chás, sucos e papa de frutas foram significativamente maiores (70,7% versus 19,7%, 63,3% versus 26,7%, 33,3% versus 4,9% e 14,4% versus 1,4%, respectivamente. CONCLUSÕES: As crianças amamentadas, quando comparadas com as não-amamentadas, apresentaram melhores hábitos no que se refere à época de introdução dos alimentos complementares.OBJECTIVE: To describe the eating habits of breastfed and non-breastfed children through the analysis of food intake by children younger than one year of age in Feira de Santana in 2001. METHODS: Cross-sectional study. The mothers of children younger than one year answered a questionnaire during the national vaccination day in 44 (71% vaccination units selected by simple stratification. 2,319 children were evaluated, representing 24.3% of the estimated population. Prevalence ratio and 95% confidence interval were calculated. Statistical significance was determined using the chi-square test. RESULTS: Non-breastfed children aged four months or younger were 8.2 and 6.7 times more likely to receive the family food (95% CI: 3.23-20.66 or vegetable soup (95% CI: 3.84-11.78, respectively. In the same age group, the prevalence of non-breastfed children receiving water, juice, and fruit was significantly higher in relation to breastfed children (70.7 vs 19.7%, 63.3 vs 26.7%, 33.3 vs 4.9% and 14.4 vs 1.4%, respectively. CONCLUSION: Breastfed children had healthier habits than non-breastfed children in terms of the introduction of complementary foods.

  14. 0~1岁儿童急性肺炎病原学研究及用药合理性分析%Etiological research and medication rationality analysis of acute pneumonia in 0~1 years old

    Institute of Scientific and Technical Information of China (English)

    王晓晖; 张楠; 黄芳

    2013-01-01

    目的 分析住院的0~1岁急性肺炎儿童呼吸道病原学结果、临床特征,评价抗菌药物使用的合理性.方法 2010年12月至2012年11月我院收治34例肺炎患儿,咽拭子送北京市疾病预防控制中心进行流感病毒核酸等快速检测,痰液送院内细菌室进行细菌培养.儿童药物利用指数(children drug utilization index,cDUI)评价抗菌药物用药剂量合理性,cDUI接近1.0时用药剂量合理.药物的用药频度(defined daily dose statistic,DDDs)数值大即临床对此药选择倾向性大.结果 34例急性肺炎患儿中,病毒感染21例,细菌感染9例,混合感染4例.存在基础疾病发生细菌性肺炎(4/9)的机会高于病毒感染(5/21)(P<0.001),有呼吸道感染患者接触史患儿病毒检出率(12/21)高于细菌检出率(4/9)(P=0.01),无交叉感染危险时,婴儿更易出现细菌感染(P=0.006).25例病毒检测阳性患儿痰培养见条件致病菌定植13例,致病菌4例.细菌感染时抗菌药物联用比例(4/9)高于混合感染(1/4)(P =0.001),各组抗菌药物使用天数差异无统计学意义(P=0.29).本研究共涉及7种抗菌药物,头孢曲松(DDDs=1813.45、总用药187 d)和头孢呋新(DDDs=1513.73、总用药162 d)用药频度、总用药天数高于其余5种抗菌药物.所有剂型抗菌药物cDUI均≤1.0,由高到低分别是:阿莫西林克拉维酸钾(cDUI=1.0)、头孢呋辛(cDUI =0.89)、头孢曲松(cDUI=0.87)、阿奇霉素口服剂和头孢吡肟(cDUI=0.80)、麦迪霉素口服剂(cDUI=0.75)、青霉素注射剂(cDUI=0.50).结论 病毒是本次婴儿急性肺炎的主要病原,病毒为细菌定植提供条件,头孢曲松的过多使用加剧条件致病菌致病风险.部分患儿抗菌药物疗程长或联合使用属于不合理用药.%Objective To analyze the etiological results and clinical characteristics in infants with acute pneumonia at the age of 0 ~ 1 years and to evaluate the rationality of the use of antibiotics.Methods Thirty-four infants hospitalized during Dec 2010 to Nov 2012 were selected.The throat swabs were sent to the Beijing Disease Prevention and Control Center for rapid nucleic acid test for influenza; the sputum was sent to the bacteriological laboratory of the hospital for the bacterial culture.Children drug utilization index (cDUI)was used to assess the rationality of the medication amount of antibiotic drugs.For defined daily dose statistic (DDDs),the larger the value of DDDs,the more frequent the clinical use of the drug.Results In the confirmed cases of acute pneumonia,21 cases were of viral infection,9cases were of bacterial infection and 4 cases were of mixed infection.The probability of bacterial pneumonia (4/9) was higher than that of viral pneumonia(5/21) in the case with underlying disease (P <0.001) ;the virus detection rate(12/21) of children with contact history with respiratory tract infection patients was higher than bacteria detection rate(4/9)(P =0.01).In case of no risk of cross infection,the infants were more susceptible to bacterial infection (P =0.006).The sputum culture of 25 cases of positive virus detection showed 13 cases of colonization of conditional pathogenic bacteria and 4 cases of pathogenic bacteria.The ratio of combination use of antibiotic drugs in case of bacterial infection (4/9) was higher than that in mixed infection (1/4) (P =0.001).The durations of the use of antibiotic drugs for every group showed no statistical difference (P =0.29).This research involved 7 antibiotic drugs.The medication frequencies and durations of ceftriaxone (DDDs =1813.45,total medication duration =187 days) and cefuroxirne (DDDs =1513.73,total medication duration =162 days) were higher than those of the other 5 antibiotic drugs.The cDUI of all drugs ≤ 1.0.The decreasing order of drugs by cDUI was amoxicillin and clavulanate potassium (cDUI =1.0),cefuroxime (cDUI=0.89),ceftriaxone (cDUI =0.87),azithromycin oral agent and cefepime (cDUI =0.80),midecamycin oral agent (cDUI =0.75) and penicillin injections (cDUI =0.50).Conclusion Virus is the main pathogen of t

  15. Seroprevalence of Toxoplasma gondii infection in captive mammals in three zoos in Mexico City, Mexico.

    Science.gov (United States)

    Alvarado-Esquivel, Cosme; Gayosso-Dominguez, Edgar Arturo; Villena, Isabelle; Dubey, J P

    2013-09-01

    Antibodies to Toxoplasma gondii were determined in 167 mammals in three zoos in Mexico City, Mexico, using the modified agglutination test (MAT). Overall, antibodies to T. gondii were found in 89 (53.3%) of the 167 animals tested. Antibodies were found in 35 of 43 wild Felidae: 2 of 2 bobcats (Lynx rufus); 4 of 4 cougars (Puma concolor); 10 of 13 jaguars (Panthera onca); 5 of 5 leopards (Panthera pardus); 7 of 7 lions (Panthera leo); 2 of 3 tigers (Panthera tigris); 2 of 3 ocelots (Leopardus pardalis); 2 of 2 Sumatran tigers (Panthera tigris sumatrae); lof 2 Jaguarundi (Herpailurus jagouaroundi); but not in 0 of 2 oncillas (Leopardus tigrinus). Such high seroprevalence in wild felids is of public health significance because of the potential of oocyst shedding. Four of 6 New World primates (2 of 2 Geoffroy's spider monkeys [Ateles geoffroyi], 1 of 3 Patas monkeys [Erythrocebus patas], and 1 of 1 white-headed capuchin [Cebus capucinus]) had high MAT titers of 3,200, suggesting recently acquired infection; these animals are highly susceptible to clinical toxoplasmosis. However, none of these animals were ill. Seropositivity to T. gondii was found for the first time in a number of species. PMID:24063119

  16. As circunstâncias do processo de reconfiguração da escola profissional de assistência a psicopatas do Distrito Federal Las circunstancias del proceso de reconfiguración de la escuela profesional de ayuda a psicópatas del Districto Federal The circumstances of the reconfiguration process of the professional school of assistance to psychopaths of the Federal District

    Directory of Open Access Journals (Sweden)

    Wellington Mendonça de Amorim

    2006-08-01

    Full Text Available Estudo histórico-social baseado em análise documental. Trata das circunstâncias do processo de reconfiguração da Escola Profissional de Enfermeiros e Enfermeiras do Serviço de Assistência a Psicopatas do Distrito Federal, na primeira metade do século XX, futura Escola de Enfermagem Alfredo Pinto, da Universidade Federal do Estado do Rio de Janeiro. OBJETIVOS: Descrever os movimentos que a saúde pública e a psiquiatria desenvolveram, no âmbito do recém-organizado Ministério da Educação e Saúde Pública, para se adequarem às políticas do início do período Vargas; e analisar as características da Escola Profissional de Enfermeiros e Enfermeiras e da Escola Anna Nery que correspondiam a visões distintas. Os campos da saúde pública, da psiquiatria e da enfermagem se estruturaram a partir dos princípios de visão e divisão, que orientaram as lutas, as controvérsias e as competições entre os diversos agentes envolvidos e impuseram os limites e as possibilidades históricas nestas duas escolas de enfermagem, no Distrito Federal.Estudio histórico-social basado en análisis documental. Se ocupa de las circunstancias del proceso de reconfiguración de la Escuela Profesional de Enfermeros y Enfermeras del Servicio de Ayuda a Psicópatas del Districto Federal, en la primera mitad del siglo XX, futura Escuela de Enfermería Alfredo Pinto, de la Universidad Federal del Estado de Rio de Janeiro. OBJETIVOS: Describir los movimientos que la salud pública y la psiquiatría habían desarrollado, en el ámbito recién-organizado del Ministerio de Educación y Salud Pública, para ajustarse a la política del inicio del período Vargas; y analizar las características de la Escuela Profesional de Enfermeros y Enfermeras y de la Escuela Anna Nery lo que correspondía a visiones distintas. Los campos de la salud pública, de la psiquiatría y de la enfermería fueron estructurados a partir de los principios de visión y división, que

  17. Sobredentadura metálica en paciente bruxópata

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    Carmen de los Milagros García Alguacil

    2014-11-01

    Full Text Available Se presenta el caso de un paciente masculino de 49 años de edad que acudió a la consulta de prótesis, el mismo había recibido tratamiento de estomatología general integral, donde se le sugirió la exodoncia de los dientes anteroinferiores, por la pérdida de la mitad de sus coronas anatómicas. Se le realizaron exámenes radiográficos y test de vitalidad, comprobando la vitalidad de los dientes; se le diagnosticó una disfunción masticatoria producto del hábito del bruxismo y se procedió a realizar una prótesis parcial removible metálica inferior (sobredentadura, la cual permitió controlar el hábito parafuncional y lograr la rehabilitación en un mismo tratamiento. Además, se logró devolver la funcionabilidad y la integridad de los dientes remanentes (sin necesidad de realizar tratamientos pulporradiculares, restaurando la dimensión vertical oclusiva y el contorno facial. Se propuso este tratamiento combinado, como alternativa eficaz en el manejo del bruxismo en pacientes parcialmente desdentados

  18. Marchenko-Pastur Theorem and Bercovici-Pata bijections for heavy-tailed or localized vectors

    CERN Document Server

    Benaych-Georges, Florent

    2012-01-01

    The celebrated Marchenko-Pastur theorem gives the asymptotic spectral distribution of sums of random, independent, rank-one projections. Its main hypothesis is that these projections are more or less uniformly distributed on the first grassmannian, which implies for example that the corresponding vectors are delocalized, i.e. are essentially supported by the whole canonical basis. In this paper, we propose a way to drop this delocalization assumption and we generalize this theorem to a quite general framework, including random projections whose corresponding vectors are localized, i.e. with some components much larger than the other ones. The first of our two main examples is given by heavy tailed random vectors (as in a model introduced by Ben Arous and Guionnet or as in a model introduced by Zakharevich where the moments grow very fast as the dimension grows). Our second main example is given by vectors which are distributed as the Brownian motion on the unit sphere, with localized initial law. Our framewor...

  19. Domingo de psicópata: análisis de la violencia en TV

    OpenAIRE

    Lic. Blas G. Fernández

    1998-01-01

    El presente trabajo describe los aspectos relacionados con la cantidad y calidad de las producciones que se presentan en la programación televisiva y con la tipología, los actores, las frecuencias y los tiempos de la violencia, que aún cuando pueda resultar recargado de datos minuciosos, permite enmarcar a la mayoría de los programas, en el caso de las televisoras nacionales en Venezuela, como simples discursos y modalidades de distracción, poseedores de una exagerada cantidad de mensajes y a...

  20. The effect of early communication with infants on language development of children aged 1 year old in the city%婴儿早期沟通对城市1岁小儿语言发展的影响

    Institute of Scientific and Technical Information of China (English)

    郝波; Fletcher P; 赵更力; 周敏; 张文坤; 张小松; 陈丽君; 梁卫兰; 张致祥; Tardif T

    2008-01-01

    目的:了解小儿语言发育水平及早期沟通对小儿语言发展的影响.方法:采用定量研究方法,对在同一家医院出生的800对正常足月儿及其母亲,分别于42天、6个月及12个月时用家庭背景问卷,于12个月时用"中文早期语言与沟通发展量表简表"(CCDI)及家庭背景问卷对母亲进行面对面问卷调查.用均数、中位数和率描述语言发展水平,用两独立样本秩和检验分析婴儿早期沟通对小儿语言发展的影响.结果:12个月时,71.6%小儿至少会用1个手势,69.0%会理解或表达至少1个词.1岁时小儿手势得分中位数为6.0(0~10),词汇得分中位数为85.0(0~194).父母在42天内、1~6个月内经常与孩子进行语言交流、给孩子做皮肤按摩、亲自养育孩子,则小儿语言得分较高.结论:婴儿早期沟通利于1岁时小儿语言发展.

  1. EFFECTS OF P APPLICATION ON N AND P ABSORPTION AND SUGAR ACCUMULATION BY 1-YEAR-OLD ALOE VERA IRRIGATED WITH SEAWATER%施磷对海水灌溉下一年生芦荟氮磷吸收及糖分积累的影响

    Institute of Scientific and Technical Information of China (English)

    邵晶; 刘玲; 刘兆普; 宁建凤; 郑青松

    2008-01-01

    在对大田海水灌溉试验的基础上,进行海水灌溉下的肥料试验。库拉索芦荟(Aloe vera)是一种CAM光合碳同化途径的多年生旱生经济植物,具有一定的耐盐性。在国外,芦荟研究的成果被广泛应用在医药、保健、食品等行业,已形成一大产业。最近的研究报告表明,与其他植物一样,盐分胁迫造成芦荟体内盐分积累、营养元素缺失,

  2. ¡Cuídese, no meta la pata!: sexualidad juvenil en escolares de Medellín (Colombia)

    OpenAIRE

    Doris Elena Ospina Muñoz; Margarita María Gómez Gómez; Marcela Carrillo Pineda

    2013-01-01

    Objetivo: Discutir con escolares, mediante taller educativo, resultados de investigaciones sobre sexualidad juvenil e identificar ejes para la educación sexual y la formación de docentes. Metodología: Estudio cualitativo sobre sexualidad con escolares de grado 10º en Medellín, Colombia (2008-2011). Previo consentimiento se realizaron actividades educativas sobre imagen corporal, disonancia cognitiva, maternidad y paternidad adolescente, derechos de la comunidad LGBTI y ética sexual. Se analiz...

  3. ¡Cuídese, no meta la pata!: sexualidad juvenil en escolares de Medellín (Colombia

    Directory of Open Access Journals (Sweden)

    Doris Elena Ospina Muñoz

    2013-12-01

    Full Text Available Objetivo: Discutir con escolares, mediante taller educativo, resultados de investigaciones sobre sexualidad juvenil e identificar ejes para la educación sexual y la formación de docentes. Metodología: Estudio cualitativo sobre sexualidad con escolares de grado 10º en Medellín, Colombia (2008-2011. Previo consentimiento se realizaron actividades educativas sobre imagen corporal, disonancia cognitiva, maternidad y paternidad adolescente, derechos de la comunidad LGBTI y ética sexual. Se analizaron evidencias escritas bajo la modalidad de discusión de expertos. Hallazgos: Los jóvenes reconocieron la sexualidad como asunto central que requiere apropiación del cuerpo, reflexividad y comunicación efectiva con padres y maestros; sin embargo, prevalece en ellos la visión trágica de la vivencia sexual. Conclusión: Los adolescentes requieren educación para la libertad, donde participen de espacios propuestos para ellos o creados por ellos, según sus necesidades y contextos y puedan tomar decisiones autónomas y responsables.

  4. Las patas en la fuente y la comunidad organizada: dislocación comunitaria e identidad en los orígenes del peronismo

    Directory of Open Access Journals (Sweden)

    Pablo Pizzorno

    2013-06-01

    Full Text Available El presente trabajo se concentra en el proceso de constitución identitaria del peronismo, retomando el lugar que ocupa la identidad en determinados estudios canónicos sobre los orígenes del peronismo y en clave de respuesta a los límites de las explicaciones basadas en el racionalismo instrumental. A partir de allí, se indaga en la conformación de un nuevo sujeto popular, articulado a partir de la interpelación peronista e identificado en la representación con Perón, cuya emergencia agrietó decisivamente el orden tradicional. Dicho proceso se plasmó en la llamada “crisis de la deferencia”, entendida como el fin de la aceptación de un lugar establecido en un orden hegemónico, expresando así un quiebre de los lugares asignados previamente en la comunidad política. Esta dislocación comunitaria de origen marcó constitutivamente al régimen peronista –donde convivieron tensamente tendencias orientadas al orden y a la ruptura– atentando contra los intentos de sutura estatal de aquella ruptura inicial. Esta última reflexión es guiada por el aporte de una serie de teorizaciones sobre el populismo como matriz específica en el marco de las Identidades políticas.

  5. Synthesis of Biotin Linkers with the Activated Triple Bond Donor [p-(N-propynoylamino)toluic Acid] (PATA) for Efficient Biotinylation of Peptides and Oligonucleotides

    OpenAIRE

    Martina Jezowska; Joanna Romanowska; Burcu Bestas; Ulf Tedebark; Malgorzata Honcharenko

    2012-01-01

    Biotin is an important molecule for modern biological studies including, e.g., cellular transport. Its exclusive affinity to fluorescent streptavidin/avidin proteins allows ready and specific detection. As a consequence methods for the attachment of biotin to various biological targets are of high importance, especially when they are very selective and can also proceed in water. One useful method is Hüisgen dipolar [3+2]-cycloaddition, commonly referred to as “click chemist...

  6. Ocular oxyspirurosis of primates in zoos: intermediate host, worm morphology, and probable origin of the infection in the Moscow zoo

    Directory of Open Access Journals (Sweden)

    Ivanova E.

    2007-12-01

    Full Text Available Over the last century, only two cases of ocular oxyspirurosis were recorded in primates, both in zoos, and two species were described: in Berlin, Germany, Oxyspirura (O. conjunctivalis from the lemurid Microcebus murinus, later also found in the lorisid Loris gracilis; in Jacksonville, Florida, O. (O. youngi from the cercopithecid monkey Erythrocebus patas. In the present case from the Moscow zoo, oxyspirurosis was recorded in several species of Old World lemuriforms and lorisiforms, and some South American monkeys. i The intermediate host was discovered to be a cockroach, as for O. (O. mansoni, a parasite of poultry. The complete sequence identity between ITS-1 rDNA from adult nematodes of the primate and that of the larval worms from the vector, Nauphoete cinerea, confirmed their conspecificity. ii Parasites from Moscow zoo recovered from Nycticebus c. coucang were compared morphologically to those from other zoos. The length and shape of the gubernaculum, used previously as a distinct character, were found to be variable. However, the vulvar bosses arrangement, the distal extremity of left spicule and the position of papillae of the first postcloacal pair showed that the worms in the different samples were not exactly identical and that each set seemed characteristic of a particular zoo. iii The presence of longitudinal cuticular crests in the infective stage as well as in adult worms was recorded. Together with several other morphological and biological characters (long tail and oesophagus, cockroach vector, this confirmed that Oxyspirura is not closely related to Thelazia, another ocular parasite genus. iv The disease in the Moscow zoo is thought to have started with Nycticebus pygmaeus imported fromVietnam, thus the suggestion was that Asiatic lorisids were at the origin of the Moscow set of cases. The natural host(s for the Berlin and Jacksonville cases remain unknown but they are unlikely to be the species found infected in zoos

  7. Estudio sobre un diagnóstico en patología mental, y dictamen sobre la capacidad fisio-psíquica de un psicópata hereditario, en la fase melancólica

    OpenAIRE

    LLinas, Pablo A.

    2012-01-01

    En mi condición de perito en la segunda instancia del juicio contradictorio que siguen entre sí los hermanos José María y Timoleón Rueda Gómez, con el mayor respeto os pido licencia para añadir a mi dictamen una digresión, a moda de proemio, y unos ligeros comentos a la sentencia del señor Juez, por si estos apéndices que me permito agregar no ajustaren exactamente entre los carriles que la práctica forense tiene fijados para estos casos.

  8. Anti-inflammatory activity of Momordica charantia in edema paw and in cortisol seric modulation; Potencial antiinflamatorio da Momordica charantia no edema de pata e na modulacao do cortisol serico

    Energy Technology Data Exchange (ETDEWEB)

    Magnata, Simey S.L.P. [Pernambuco Univ., Recife, PE (Brazil). Dept. de Energia Nuclear]. E-mail: sfmagnata@terra.com.br; Correia, Marilia B.L.; Brandao, Jose Odinilson C.; Souza, Grace M.L.; Catanho, Maria Teresa J.A. [Pernambuco Univ., Recife, PE (Brazil). Dept. de Biofisica e Radiobiologia; Terra, Daniele A.; Amorim, Lucia F. [Rio Grande do Norte Univ., Natal, RN (Brazil). Dept. de Fisiologia

    2005-07-01

    The first sources that the humanity disposed to disease's treatment was plants and herbs. The Momordica charantia, Melao de Sao Caetano (bitter melon), occur in South and Central America and in East, it has been used as an anti-diabetic agent, anti-tumor, anti-helmintic and anti-ulcerogenic. The objective of this study is to research the Momordica charantia's activity on inflammatory process and the change on cortisol hormone seric concentration. To evaluate the anti-inflammatory activity were used mice (n=5) in test groups (30,60,100,250 mg/kg of extract) and control (negative and positive) groups (AAS 250 mg/kg and NaCl 0,9%); the inflammatory agent (carrageenan 1% p/v, 0,1 mL) was injected into right hind paw planter surface, 30 min after, the groups received each dose IP of extract, AAS and solution saline respectively; 4 hour after the mice was sacrificed and the difference between right and left hind foot mass was measured. There was a significant reduction (p<0,05)in carrageenan-induced edema paw at test from control group, the best result was obtained at 60 mg/kg dose which inhibits edema formation by 50%. To determinate the cortisol concentrations male Wistar rats, were divided in three groups: control, test A (2 hours of treatment) and test B (4 hours of treatment). The control group received 0,25 mL of saline solution (NaCl) 0,9% and the test groups 0,25 mL of Momordica charantia's aqueous extract, obtained by decoction of green leaves, (31,16 mg/kg animal); all by via IP. After the treatment, the animals were sacrificed and the serum obtained for realization of dosages. The cortisol was determined through radioimmunoassay. The results showed a reduction on a average by 83,9% from control group. The Momordica charantia's extract showed a high anti-inflammatory effect and was capable of reducing the seric cortisol on normal rats. (author)

  9. Phototherapy with low intensity laser in carrageenan-induced acute inflammatory process in mice paw - dosimetry studies; Fototerapia com laser em baixa intensidade em processo inflamatorio agudo induzido por carragenina em pata de camundongos - estudos de dosimetria

    Energy Technology Data Exchange (ETDEWEB)

    Meneguzzo, Daiane Thais

    2010-07-01

    The importance of modulation of inflammation on the treatment of inflammatory diseases and the difficulty in determining the laser irradiation parameters has led us to study the effects of different protocols of phototherapy with low intensity laser (power, energy, time and place of irradiation) in the treatment and prevention of edema in acute inflammatory process using the experimental model of paw edema induced by carrageenan (CGN) in three strains of mice (Balb-c, Swiss and C57BL/6). The first stage of the study evaluated different combinations of energy (1J and 3J) with different powers (30, 60 and 100mW) in Balb-C mice paw irradiated 1 and 2h after injection of CGN. The second stage studied different combinations of location (foot, inguinal lymph nodes and both) and exposure time (2 and 1h before, 1h and immediately before the CGN, 1 and 2h and 3.5 and 4.5h after CGN) using fixed irradiation parameters (1J, 100mW, 35J/cm{sup 2}, spot area of 0.028 cm{sup 2}). The third stage compared different strains of mice Balb-c and C57BL/6) in the best local and time parameters found in step 2. At all stages, we evaluated the change in paw volume by plethysmography and inflammatory infiltrate by histomorphometry or analysis of myeloperoxidase (MPO). The results showed that laser phototherapy treated and prevented edema and modulated the inflammatory process with paw and inguinal lymph nodes irradiations accordingly with the parameters and mice strain used. (author)

  10. On the training of Brazilian homeopaths. Sobre la capacitación de los homeópatas brasileños. Sobre a formação dos homeopatas brasileiros.

    Directory of Open Access Journals (Sweden)

    Renato Sampaio Azambuja

    2007-01-01

    Full Text Available Although the credibility of homeopathy is raising among the Brazilian general population and government and academic institutions, the training of homeopaths disagrees with the exigences presented by clinical practice. This article discusses a proposal to reformulate the pedagogical practice, centered on the student as the builder of knowledge. The training basic block would be the small group, composed by students and a tutor; all activities would be performed in the concrete practice situation. The full process would unfold in three stages: 1 deconstruction of previous knowledge and establishment of new notions; 2 deepening into the homeopathic specific features; 3 discussion of homeopathy philosophical and epistemological issues, as well as its conection to related areas.

  11. Inhibition of carrageenan-induced expression of tissue and plasma prekallikreins mRNA by low level laser therapy in a rat paw edema model Inibição da expressão de RNA mensageiro de pré-calicreínas tecidual e plasmática pela laserterapia em modelo de edema de pata induzido pela carragenina em ratos

    OpenAIRE

    Moisés P. Silva; Flávia Bortone; Marcelo P. Silva; Thiago R. Araújo; Maricília S. Costa; José A. Silva Júnior

    2011-01-01

    BACKGROND: Low level laser therapy (LLLT) has been used clinically in order to treat inflammation, where tissue and plasma prekallikrein have crucial importance. Plasma prekallikrein (PPK) is synthesized by the hepatocytes and secreted into the bloodstream, where it participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. Tissue prekallikrein is associated with important disease states (including cancer, inflammation, and neurodeg...

  12. Inhibition of carrageenan-induced expression of tissue and plasma prekallikreins mRNA by low level laser therapy in a rat paw edema model Inibição da expressão de RNA mensageiro de pré-calicreínas tecidual e plasmática pela laserterapia em modelo de edema de pata induzido pela carragenina em ratos

    Directory of Open Access Journals (Sweden)

    Moisés P. Silva

    2011-02-01

    Full Text Available BACKGROND: Low level laser therapy (LLLT has been used clinically in order to treat inflammation, where tissue and plasma prekallikrein have crucial importance. Plasma prekallikrein (PPK is synthesized by the hepatocytes and secreted into the bloodstream, where it participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. Tissue prekallikrein is associated with important disease states (including cancer, inflammation, and neurodegeneration and has been utilized or proposed as clinically important biomarker or therapeutic target of interest. OBJECTIVE: To evaluate if LLLT modulates tissue and plasma prekallikreins mRNA expression in the carrageenan-induced rat paw edema. METHODS: Experimental groups were assigned as followed: A1 (Control-saline, A2 (Carrageenan-only, A3 (laser 660nm only and A4 (Carrageenan + laser 660nm. Edema was measured by a plethysmometer. Subplantar tissue was collected for the quantification of prekallikreins mRNA by Real time-Polymerase Chain Reaction. RESULTS: A significantly decrease in the edema was observed after laser irradiation. Expression of prekallikreins increased after carrageenan injection. Tissue and plasma prekallikrein mRNA expression significantly decreased after LLLT's 660nm wavelength. CONCLUSION: These results suggest that expression of tissue and plasma prekallikreins is modulated by LLLT, which can be used in clinical practice due to its anti-inflammatory effects.CONTEXTUALIZAÇÃO: A laserterapia de baixa potência tem sido usada para o tratamento de processos inflamatórios diversos em que a calicreína tecidual e a plasmática possuem participação ativa. A pré-calicreína plasmática (PPK é sintetizada pelos hepatócitos e secretada na corrente sanguínea, onde participa da ativação da coagulação, fibrinólise, geração de cininas e inflamação. A pré-calicreína tecidual está associada com importantes doenças (incluindo câncer, inflamação e neurodegeneração e tem sido utilizada ou sugerida clinicamente como importante biomarcador ou alvo terapêutico. OBJETIVO: Avaliar se a laserterapia altera a expressão gênica da pré-calicreína tecidual e da plasmática no modelo de inflamação aguda induzida pela carragenina. MÉTODOS: Quarenta ratos foram separados em quatro grupos experimentais: A1 (controle, A2 (carragenina, apenas, A3 (laser 660nm, apenas e A4 (Carragenina + laser 660nm. O edema foi medido por um pletismômetro. Tecido subplantar foi coletado para a quantificação de RNA mensageiro (RNAm de pré-calicreínas tecidual e plasmática por PCR em tempo real. RESULTADOS: Observou-se uma diminuição significativa no volume de edema após irradiação com laser 660nm. A expressão de RNAm de pré-calicreínas tecidual e plasmática aumentou após a inoculação de carragenina, entretanto a expressão gênica das pré-calicreínas diminuiu significantemente após laserterapia de baixa potência de 660nm. CONCLUSÃO: Os resultados sugerem que a expressão de RNAm das pré-calicreínas tecidual e plasmática é modulada pela laserterapia de baixa potência, podendo ser alvo terapêutico para tratamento de processos inflamatórios.

  13. New species of Haematoloechus (Digenea: Plagiorchidae in the lung of the foothill yellow-legged frog Rana boylii (Anura, from Humboldt County, California, USA Especie nueva de Haematoloechus (Digenea: Plagiorchidae del pulmón de la rana de patas amarillas Rana boylii (Anura, de Humboldt County, California, Estados Unidos de América

    Directory of Open Access Journals (Sweden)

    David Zamparo

    2011-06-01

    Full Text Available A new species of Haematoloechus is described from the lungs of Rana boylii from Humboldt County, California. The new species is similar to Haematoloechus buttensis, Haematoloechus kernensis, and Haematoloechus complexus in general course of the uterus and gonad shape. It is similar to H. buttensis by having a cirrus sac terminating midway between the posterior margin of the pharynx and the anterior margin of the ovary, and having a smaller oral/ventral sucker ratio; to H. complexus by having the genital pore ventral to the pharynx, and it is similar to H. kernensis by having a larger oral sucker to pharynx width ratio. The new species is unique by lacking an extra-cecal longitudinal uterine loop from the hind-body. Molecularly, the new species differs 1.04-1.15% in partial 28S sequence with respect to H. complexus, and a monophyletic grouping of these specimens in a phylogenetic analysis of all available sequence data consistent with the species-specific status proposed herein. Evidence is also presented to suggest that specimens identified as H. buttensis in Rana pretiosa from British Columbia, Canada represents a new, but still undescribed species. The importance of conducting biological inventories of helminths, along with continued monitoring of populations, and collections based taxonomy are related.Una especie nueva de Haematoloechus es descrita de los pulmones de Rana boylii de Humboldt County, California. La especie nueva guarda semejanza con Haematoloechus buttensis, Haematoloechus kernensis, y Haematoloechus complexus en la disposición general del útero y en la forma de las gónadas. Es similar a H. buttensis en que la bolsa del cirro finaliza entre el margen posterior de la faringe y el margen anterior del ovario, y en presentar una relación menor entre la ventosa oral y el acetábulo; a H. complexus por tener el poro genital ventral a la faringe, y a H. kernensis por tener una relación mayor del ancho de la ventosa oral contra la faringe. La especie nueva es única por carecer de asas uterinas extracecales longitudinales. Molecularmente, la especie nueva muestra 1.04-1.15% de diferencia en secuencias parciales de 28S con respecto H. complexus; esta información complementa las diferencias morfológicas. También se presenta evidencia para sugerir que ejemplares identificados como H. buttensis de Rana pretiosa en British Columbia, Canadá probablemente representan una especie nueva aún no descrita. Se aborda la importancia de la realización de inventarios biológicos de helmintos, el monitoreo continuo de las poblaciones y las colecciones basadas en la taxonomía.

  14. Removal of suspended solids from the effluents of a shrimp farm by the Blood Ark Anadara tuberculosa (Sowerby, 1833 Remoción de sólidos suspendidos en los efluentes de una granja camaronera por la almeja pata de mula Anadara tuberculosa (Sowerby, 1833

    Directory of Open Access Journals (Sweden)

    Anselmo Miranda

    2009-08-01

    Full Text Available The potential of Anadara tuberculosa for bioremediation of shrimp farm effluents was evaluated in five field experiments performed in a semi-intensive shrimp farm in Sonora (NW Mexico, and yielded mean filtration, clearance and biodeposition rates of 33.10 mg/h/g, 0.41 L/h/g and 31.19 mg/h/g, respectively. This study demonstrates that A. tuberculosa adults can remove the particulate matter of a semi-intensive shrimp farms effluents.Se realizaron cinco experimentos en una granja de cultivo semi-intensivo de camarón ubicada en Sonora (Noroeste de México con el fin de verificar in situ el potencial de Anadara tuberculosa para la biorremediación de los efluentes de granjas camaroneras. Se obtuvieron tasas medias de filtración y de clarificación de 33.10 mg/h/g y 0.41 L/h/g y la de biodepositación fue 31.19 mg/h/g. Este estudio demuestra que individuos adultos de A. tuberculosa pueden remover la materia particulada de los efluentes de las granjas camaroneras semi-intensivas.

  15. On how a dentist can also be a homeopath. Sobre cómo un cirujano dentista tambiém puede ser homeópata. Das formas do cirurgião-dentista ser também homeopata.

    Directory of Open Access Journals (Sweden)

    Ruth Barbosa

    2003-01-01

    Full Text Available No Brasil, a possibilidade de atuação conjunta entre Homeopatia e Odontologia iniciou-se no final do século passado, comprovando que trocar informações e conhecimento é prática indispensável entre profissionais responsáveis e visionários. A Homeopatia oferece ao cirurgião-dentista uma filosofia que expande e aprofunda a observação de seu paciente. Ao mesmo tempo, a Odontologia assessora a remoção de obstáculos mecânicos à cura, deixando ao observador homeopata apenas o que é característico e peculiar ao paciente no ambiente estomatoglossognato-cranio-cervical.

  16. LEVEL OF CHOLESTEROL AND FATTY ACIDS IN THE EGGS OF DIFFERENT SPECIES OF POULTRY. TEORES DE COLESTEROL E ÁCIDOS GRAXOS EM OVOS DE DIFERENTES ESPÉCIES DE AVES

    Directory of Open Access Journals (Sweden)

    T. T. OLIVEIRA

    2008-08-01

    Full Text Available This work had as objective to evaluate the cholesterol level fatty acids of triacylglicerol and phosphofolipids of eggs of the different poultry species. The following results were observed: cholesterol: goose duck> turkey > chicken > quail. Fatty acids of triacylglicerols: palmitic acid: turkey > quail goose > duck chicken. Estearic acid: quail chicken> goose duck perua. Oleic acid : goose > chicken> quail duck turkey. α-Linoleic acid: chicken> turkey quail > goose duck. Arachidonic acid: turkey > quail duck> chicken> goose. Docosahexanoic acid: turkey> duck goose chicken > quail. Phospholipids of fatty acids: palmí]itic acid: duck> goose quail > chicken turkey. Estearic acid: chicken turkey > quail> goose > duck. Oleic acid: duck goose > quail > turkey> chicken. α-Linoleic acid: turkey > chicken quail > duck goose. Arachidonic acid: duck > goose > quail chicken > turkey. Docosahexanoic acid: chicken> goose > turkey> quail duck. These results can be of importance for food tables and dietetic treatment of patients.

    Este trabalho teve como objetivo avaliar o teor de colesterol, ácidos graxos de triacilgliceróis e de fosfolipídeos de ovos de diferentes espécies de aves. Foram observados os seguintes resultados: As concentrações de colesterol foram maiores na: pata ≅ gansa > perua > galinha > codorna. As concentrações de ácidos graxos de triacilgliceróis: ácido palmítico: perua> gansa codorna > galinha >pata. Ácido esteárico: codorna galinha > gansa pata perua. Ácido oléico: gansa > galinha >codorna pata perua. Ácido -linoléico: galinha >codorna > perua > gansa pata. Ácido araquidônico: perua > codorna pata > galinha> gansa. Ácido docosaexanóico: perua > pata gansa galinha > codorna. Ácidos graxos de fosfolipídeos: ácido palmítico: pata > gansa codorna > galinha perua. Ácido esteárico: galinha

  17. Advanced photoacoustic and thermoacoustic sensing and imaging beyond pulsed absorption contrast

    Science.gov (United States)

    Gao, Fei; Feng, Xiaohua; Zheng, Yuanjin

    2016-07-01

    In this paper, we review the recent progress in the photoacoustic (PA) and thermoacoustic (TA) imaging domain. Going beyond the conventional investigation of optical/microwave absorption contrast, this review will focus more on the new developments of PA and TA imaging towards multi-contrast mechanisms, such as multimodal PA/TA imaging, viscosity imaging, temperature monitoring, Doppler detection of flow speed, etc. In addition, several interesting techniques utilizing PA/TA will be reviewed, including photoacoustic-guided optical focusing, electrical circuit modeling of PA/TA effect, TA imaging with coherent continuous-wave (CW) magnetic and radio-frequency (RF) excitations, as well as its nonlinear effect. Finally, some prospects about the further improvement of PA/TA imaging techniques are suggested, followed by the conclusion.

  18. Protein (Cyanobacteria): 227779 [PGDBj - Ortholog DB

    Lifescience Database Archive (English)

    Full Text Available ZP_18822821.1 1117:4316 1118:2919 1125:192 1126:696 1160286:25 Putative peptidase PatA homolog (fragm...LSSFLNRIYYDLRNLGQTSQDRALNFAATNAFQAAQTFSEAVGAGMELDSINVSKSPFCRLDSDCWDVQLKFFDPENSRRARKVFRFTIDVSDLIPVTLGEVRSWSSPN ...

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    Full Text Available ZP_18845350.1 1117:4316 1118:2919 1125:192 1126:696 1160285:784 Putative peptidase PatA homolog (fragm...FLNRIYYDLRNLGQTSQDRALNFAATNAFQAAQTFSEAVGAGMELDSINVSKSPFCRLDSDCWDVQLKFFDPENSRRARKVFRFTIDVSDLIPVTLGEVRSWSSPY ...

  20. Protein (Cyanobacteria): 227763 [PGDBj - Ortholog DB

    Lifescience Database Archive (English)

    Full Text Available ZP_10229400.1 1117:4316 1118:2919 1125:192 1160279:2410 Putative peptidase PatA homolog (fragm...ent) Microcystis sp. T1-4 MRRTLSSFLNRIYYDLRNLGQTSQDRALNFAATNAFQAAQTFSEAVGAGMELDSINVSKSPFCRLDSDCWDVQLKFFDPENSRRARKIFRFTIDVSDLIPVTLGEVRSWSSPY ...

  1. Estimation of Genetic Parameters for Main Wool Traits in Keerqin Fine Wool Sheep

    Institute of Scientific and Technical Information of China (English)

    Mei; Hua; Gao; Fengming

    2014-01-01

    [Objective]To investigate the population genetic structure of Keerqin fine wool sheep. [Method]The genetic parameters of wool traits in Keerqin fine wool sheep were calculated by employing paternal half sib correlation method. [Results]The traits with high heritability( h≥0. 3) included wool length( 1-year old),wool yield( 1-year old) and wool yield( 2-year old); that with medium heritability( 0. 1≤h≤0. 3) included wool fineness( 1-year old),wool fineness( 2-year old),wool length( 3-year old) and wool yield( 3-year old). There were extremely significant positive correlations between wool fineness( 1-year old) and wool fineness( 2-year old),between wool fineness( 1-year old) and wool fineness( 3-year old),between wool length( 1-year old) and wool length( 2-year old),between wool length( 1-year old) and wool length( 3-year old),and between wool fineness( 2-year old) and wool fineness( 3-year old),with the correlation coefficients of 0. 653 0,0. 625 8,0. 489 6,0. 578 8,0. 578 4 and 0. 554 6 respectively. The results showed that the phenotypic correlation was poorer than genetic correlation among the wool traits. [Conclusion]The wool fineness,wool yield and body weight of Keerqin fine wool sheep all fail to meet the excellent level and need to be improved further.

  2. Methow River Steelhead - Methow River Steelhead hatchery reform research

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Steelhead in Pacific Northwest hatcheries are typically reared for release as 1-year-old smolts, rather than the 2and 3-year-old smolt life history patterns found...

  3. Disease: H00771 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available early as 1 year old (early-onset), or in adults (adult-onset), and both types have been described in famil...ies and in sporadic cases. Pharmacotherapy has been largely ineffective, and partia

  4. Estudio de las funciones verbales y aptitudes lingüísticas en la psicopatía

    OpenAIRE

    Almeida Brites, José Manuel de

    2012-01-01

    [ES] Cleckley (1976) señaló la presencia de un lenguaje hueco en el psicópata como forma de manipular. Aunque puede repetir las palabras y decir que las comprende, aparentemente no existe ninguna forma de que pueda darse cuenta de que, en realidad, no las comprende. Su empleo del lenguaje indica dificultades para exponer los argumentos sin desvíos o incoherencias sustanciales. El objetivo de este trabajo consiste en evaluar las funciones verbales y aptitudes lingüísticas en varones psicópatas...

  5. Psicopatía, violencia y criminalidad: un análisis psicológico-forense, psiquiátrico-legal y criminológico (Parte II) Psychopathy, violence and crime: a psychological-forensic, psychiatric-legal and criminological analysis (Part II)

    OpenAIRE

    J.M. Pozueco Romero; S.L. Romero Guillena; N. Casas Barquero

    2011-01-01

    La Jurisprudencia española se encuentra frecuentemente ante dictámenes periciales en los que aparecen términos como psicópata, trastorno antisocial de la personalidad, personalidad psicopática, psicópata desalmado, psicopatía epileptoide, sociopatía, etc. De esta forma, no es infrecuente que los juristas (magistrados, jueces, fiscales, abogados) se hallen desorientados ante tanta terminología que, pese a todo, en absoluto se constituyen en sinónimos. La Doctrina, por su parte, disiente de la ...

  6. Delincuente sexual en serie y alteraciones psicopáticas: una relación ocasional Repeat sex offender and psychopathic changes: An incidental relationship

    OpenAIRE

    M. Ventura Alvarez; J.A. Presentación Blasco

    2003-01-01

    Los delincuentes sexuales en serie son tomados frecuentemente como psicópatas, en parte como consecuencia de la creciente popularidad del término. Un delincuente sexual en serie es aquel que ha actuado sobre dos o más víctimas en diferentes fechas; un psicópata es un tipo de trastorno de la personalidad que exhibe un patrón duradero de conductas socialmente irresponsables que desprecian los derechos de los demás. El presente trabajo presenta un caso de violador en serie interrumpido precozmen...

  7. CMS Young Researchers Award 2013 and Fundamental Physics Scholars Award from the CMS Experiment

    CERN Document Server

    Lapka, Marzena

    2014-01-01

    Photo 2: CMS Fundamental Physics Scholars (FPSs) 1st prize: Joosep Pata, from Estonian National Institue of Chemical Physics and Biophysics / Photo 1 and 3: CMS Young Researchers Award. From left to right: Guido Tonelli, Colin Bernet, Andre David, Oliver Gutsche, Dmytro Kovalskyi, Andrea Petrucci, Joe Incandela and Jim Virdee

  8. Susceptibility of laboratory primates to infection with Mansonella ozzardi from man.

    Science.gov (United States)

    Orihel, T C; Lowrie, R C; Eberhard, M L; Raccurt, C; Kozek, W J; Tidwell, M A; Tidwell, M

    1981-07-01

    The study was undertaken to determine primates were susceptible to infection with Caribbean and/or Amazon strains of Mansonella ozzardi of man. Twenty-three animals including three chimpanzees, four squirrel monkeys, one capuchin, five rhesus and 10 patas monkeys each received, by subcutaneous or intraperitoneal injection, 25-170 infective larvae of M. ozzardi harvested either from infected Culicoides furens collected in Haiti or Simulium sp. (sanguineum complex) collected in the Colombian Amazon and transported to our laboratories in Louisiana. Patent infections were obtained in seven of 10 patas monkeys but not in any other species of primates. The prepatent period ranged in duration from 149-186 days with a mean of 168 days. All of the patas monkeys developed modest microfilaremias that persisted for as long as 1 year, the duration of our observations. Adult worms were obtained at necropsy from three of four patas monkeys. The worms were recovered from soakings of the carcass and skin rather than from the abdominal cavity and mesenteries. However, their precise habitat was not determined. PMID:7020456

  9. Singid letti! / Mari Kodres

    Index Scriptorium Estoniae

    Kodres, Mari

    2012-01-01

    Hispaania armastatuimast ja hinnatuimast toiduainest jamón ibérico'st ehk Ibeeria singist, mida tuntakse ka nime all pata negra (eesti k 'must sõrg'). Tammetõrudega toidetud Ibeeria sea lihast valmistatud parimad singid valmivad Loode-Andaluusias Sierra de Aracenas

  10. ELABORACIÓN DEL QUESO [Material gráfico

    OpenAIRE

    Anonymous

    2000-01-01

    LA QUESERA ES UN SOPORTE DE MADERA CON PATAS, CON FORMA INCLINADA Y UNAS CANALIZACIONES EN EL BORDE PARA QUE EL TABEFE ESCURRA. TRADICIONALMENTE LA ELABORACIÓN DEL QUESO SE HA RELACIONADO A LA MUJER PUES PARECE QUE LA MUJER CUENTA "CON UNA ESPECIAL DESTREZA Y PACIENCIA" NECESARIAS PARA SU ELABORACIÓN.

  11. Aging affects mechanical properties and lubricin/PRG4 gene expression in normal ligaments.

    Science.gov (United States)

    Thornton, Gail M; Lemmex, Devin B; Ono, Yohei; Beach, Cara J; Reno, Carol R; Hart, David A; Lo, Ian K Y

    2015-09-18

    Age-related changes in ligament properties may have clinical implications for injuries in the mature athlete. Previous preclinical models documented mechanical and biochemical changes in ligaments with aging. The purpose of this study was to investigate the effect of aging on ligament properties (mechanical, molecular, biochemical) by comparing medial collateral ligaments (MCLs) from 1-year-old and 3-year-old rabbits. The MCLs underwent mechanical (n=7, 1-year-old; n=7, 3-year-old), molecular (n=8, 1-year-old; n=6, 3-year-old), collagen and glycosaminoglycan (GAG) content (n=8, 1-year-old; n=6, 3-year-old) and water content (n=8, 1-year-old; n=5, 3-year-old) assessments. Mechanical assessments evaluated total creep strain, failure strain, ultimate tensile strength and modulus. Molecular assessments using RT-qPCR evaluated gene expression for collagens, proteoglycans, hormone receptors, and matrix metalloproteinases and their inhibitors. While total creep strain and ultimate tensile strength were not affected by aging, failure strain was increased and modulus was decreased comparing MCLs from 3-year-old rabbits to those from 1-year-old rabbits. The mRNA expression levels for lubricin/proteoglycan 4 (PRG4) and tissue inhibitor of metalloproteinase-3 increased with aging; whereas, the mRNA expression levels for estrogen receptor and matrix metalloproteinase-1 decreased with aging. Collagen and GAG content assays and water content assessments did not demonstrate any age-related changes. The increased failure strain and decreased modulus with aging may have implications for increased susceptibility to ligament damage/injury with aging. Lubricin/PRG4 gene expression was affected by aging and its speculated role in ligament function may be related to interfascicular lubrication, which in turn may lead to altered mechanical function with aging and increases in potential for injury.

  12. The lacrimal fossa of cercopithecoidea, with special reference to cladistic analysis of Old World monkey relationships.

    Science.gov (United States)

    Benefit, B R; McCrossin, M L

    1993-01-01

    Re-examination of lacrimal fossa patterns in extant cercopithecoids indicates that the last common ancestor of Cercopithecini and Papionini, and hence of Cercopithecinae, probably retained a maxillary contribution to the lacrimal fossa, as did the common ancestor of Colobinae. Consequently, the presence of a maxilla-lacrimal fossa cannot be used to assess the subfamily affinity of Old World monkeys. In addition to being correlated with general facial lengthening, the derived, exclusively lacrimal pattern of Erythrocebus, Mandrillus, Papio, Theropithecus and some (but not all) guenons, macaques and mangabeys may be associated with extreme narrowing of the interorbital septum. Moreover, the derived condition may have evolved in response to independent exploitation of open country habitats as it enhances protection of the lacrimal sac and serves to reduce eye infection in terrestrial species.

  13. SALINE WATER RESOURCES IN CLUJ-NAPOCA SURROUNDINGS

    Directory of Open Access Journals (Sweden)

    B. CZELLECZ

    2016-03-01

    Full Text Available Saline waters are usually researched in those places where it is used for balneotherapy or other industrial purposes. The aim of this study is to describe the saline water sources from less known areas, as they are an important natural mineral water resource. Twenty nine water samples were analyzed from Cojocna-Pata-Sopor region, thirteen of them can be considered saline waters. The visited locations are 21, 15 and 3 km far from Cluj-Napoca. Highly concentrated springs are to be found in the old mine area from Pata village and in the slough from Cojocna. Beside the well known saline lakes from Cojocna, five other saline lakes were identified; most of them are having artificial origin.

  14. Herodot zur skythischen Sprache

    DEFF Research Database (Denmark)

    Hinge, George

    2005-01-01

    Herodots skythiske etymologier for fokenavnene Arimaspoi og Oiorpata må opgives ("enøjet" = arima "en" + spu "øje" og "manddræbende" = oior "mand" + pata "dræbe"). Artiklens forfatter foreslår i stedet nye skythiske forklaringer (*arjataspāh "hesterig" og *aiwawarakāta "enbrystet"). Herodots fals...

  15. Evaluación neuropsicológica en internos penitenciarios mexicanos.

    Directory of Open Access Journals (Sweden)

    Nallely Arias García

    2010-07-01

    Full Text Available El objetivo de esta investigación fue evaluar psicológica y neuropsicológicamente a un grupo de internos violentos de una Penitenciaría Federal en México y caracterizarlos de acuerdo con la clasificación de impulsividad y premeditación de Barratt (Barratt, Stanford, Lynn, Liebman y Kent, 1999 y utilizando la clasificación de Hare (1991 de psicopatía, para analizar las diferencias entre los grupos de acuerdo a diferentes clasificaciones. La muestra fue integrada por 75 participantes, 50 internos y 25 controles para el estudio 1 (impulsivos vs premeditados y 54 sujetos para el estudio 2 (no psicópatas vs psicópatas. Se administraron la Escala de Impulsividad de Plutchik, el Inventario de Hostilidad de Buss-Durkee, la batería neuropsicológica NEUROPSI ATENCIÓN y MEMORIA (Ostrosky-Solís, Gómez, Ardila, Rosselli, Pineda y Matute; 2003 y la batería de Funciones Frontales y Ejecutivas (Flores, Ostrosky y Lozano, 2008. Los resultados indican que las poblaciones violentas independientemente de su clasificación pueden ser diferenciadas de la población no violenta. Sin embargo, no se encontraron diferencias significativas en las evaluaciones neuropsicológicas entre los grupos impulsivo y premeditado, mientras que los resultados entre los no psicópatas y psicópatas muestran diferencias significativas en distintos dominios cognoscitivos. Los resultados se discuten en términos de la base anatómica que subyace a dichos procesos.

  16. The Kathmandu valley : A study in regional geography

    OpenAIRE

    Haffner, Willibald

    1981-01-01

    Anyone studying the map of the Kathmandu valley is struck by the almost plastic contrast between the valley bottom and its mountainous, wooded frame dissected by U-shaped valleys. A naturally favourable situation, together with a position that controls the pass of one of the most important trade and pilgrimage routes in the central Himalayas provided decisive impulses for the development of the three largest towns of Nepal: Kathmandu, Pata and Bhaktapur. More than half of the 600.000 inhabita...

  17. Simulación de un Robot Hexápodo Bioinspirado en el Tenebrio

    Directory of Open Access Journals (Sweden)

    Juan Pablo Rodríguez-Calderón

    2015-06-01

    Full Text Available Los insectos son base fundamental en el estudio de la robótica reactiva ya que estos poseen características biológicas y motrices que son de interés para ser implementadas en robots bioinspirados, teniendo en cuenta el desempeño de éstos en diferentes áreas. Por otra parte los animales hexápodos poseen omnidireccionalidad y estabilidad, debido a la formación del trípode de apoyo, el cual se crea en sus patas al dar un paso, lo cual les permite sobrepasar diferentes obstáculos con facilidad y velocidad constante. En este proyecto se implementa el sistema locomotor del insecto Tenebrio debido a la facilidad con que se pueden apreciar sus movimientos. Se analiza el desplazamiento de las patas del insecto en diferentes trayectorias, vistas y terreno plano, posteriormente se encontraron los parámetros, ecuaciones y restricciones que limitan los diferentes eslabones de cada una de las patas del Tenebrio, esto se realizó por medio de un análisis de imágenes. Finalmente la información recogida se implementa en la plataforma MATLAB para determinar las características de movimiento, estabilidad y desplazamiento.

  18. Detection of Bordetella pertussis using a PCR test in infants younger than one year old hospitalized with whooping cough in five Peruvian hospitals

    Directory of Open Access Journals (Sweden)

    María Esther Castillo

    2015-12-01

    Conclusion: An increase in pertussis cases has been reported in recent years in Peru, despite national immunization efforts. Surveillance with PCR for B. pertussis is essential, especially in infants less than 1 year old, in whom a higher rate of disease-related complications and higher mortality have been reported.

  19. Orbital lymphomatoid granulomatosis - a rare cause of proptosis

    Energy Technology Data Exchange (ETDEWEB)

    Du Toit, Jacqueline; Kilborn, Tracy [Department of Radiology, Red Cross Children' s Hospital, Rondebosch (South Africa); Eyssen, Ann van [Department of Oncology, Red Cross Children' s Hospital, Rondebosch (South Africa); Pillay, Komala [Department of Pathology, Red Cross Children' s Hospital, Rondebosch (South Africa)

    2015-07-15

    A 1-year-old girl with unilateral proptosis was found to have primary orbital lymphomatoid granulomatosis - a condition rarely occurring in children. This multisystem angiocentric, angiodestructive, lymphoproliferative disease typically involves the lungs, with ocular involvement being extremely uncommon. Our case serves to illustrate the imaging findings of this unusual condition and highlight a rare cause of proptosis. (orig.)

  20. Investigation of the pathogenesis of transplacental transmission of Aleutian mink disease parvovirus in experimentally infected mink

    DEFF Research Database (Denmark)

    Broll, S.; Alexandersen, Søren

    1996-01-01

    The transplacental transmission of Aleutian mink disease parvovirus (ADV) was studied in experimental infection of 1-year-old female non-Aleutian mink. The ADV-seronegative female mink were inoculated,vith ADV prior to mating or after the expected implantation of the embryos during pregnancy...

  1. Isolation of new species “Peptoniphilus phoceensis” from human gut

    OpenAIRE

    Mourembou, G.; Traore, S.I.; J. Rathored; Khelaifia, S.; Lagier, J.C.; Michelle, C.; Raoult, D.; Million, M.

    2016-01-01

    Taxonogenomics coupled with culturomics leads to descriptions of new bacteria. Thanks to this strategy, we report the main characteristics of “Peptoniphilus phoceensis” strain SIT15, a new bacterium isolated from a stool sample of a 1-year-old healthy Senegalese boy.

  2. Creating an Amazing Montessori Toddler Home Environment

    Science.gov (United States)

    Woo, Stephanie

    2014-01-01

    The author states that raising her twins the Montessori way has made her life easy. Imagine two 1-year-olds eating entire meals on their own, setting their own tables by 20 months, and becoming potty-trained before 2. These are not statistics found in just one household. Children raised the Montessori way can take care of themselves and their…

  3. One-Year-Olds Think Creatively, Just Like Their Parents

    Science.gov (United States)

    Hoicka, Elena; Mowat, Rachael; Kirkwood, Joanne; Kerr, Tiffany; Carberry, Megan; Bijvoet-van den Berg, Simone

    2016-01-01

    Creativity is an essential human ability, allowing adaptation and survival. Twenty-nine 1-year-olds and their parents were tested on divergent thinking (DT), a measure of creative potential counting how many ideas one can generate. Toddlers' and parents' DT was moderately to highly correlated. Toddlers showed a wide range of DT scores, which were…

  4. Sign Facilitation in Word Recognition.

    Science.gov (United States)

    Wauters, Loes N.; Knoors, Harry E. T.; Vervloed, Mathijs P. J.; Aarnoutse, Cor A. J.

    2001-01-01

    This study examined whether use of sign language would facilitate reading word recognition by 16 deaf children (6- to 1 years-old) in the Netherlands. Results indicated that if words were learned through speech, accompanied by the relevant sign, accuracy of word recognition was greater than if words were learned solely through speech. (Contains…

  5. Toll-like receptor 4 polymorphism associated with the response to whole-cell pertussis vaccination in children from the KOALA study

    NARCIS (Netherlands)

    Banus, Sander; Bottema, Renske W. B.; Siezen, Christine L. E.; Vandebriel, Rob J.; Reimerink, Johan; Mommers, Monique; Koppelman, Gerard H.; Hoebee, Barbara; Thijs, Carel; Postma, Dirkje S.; Kimman, Tjeerd G.; Stelma, Foekje F.

    2007-01-01

    We examined the association between haplotype tagging single-nucleotide polymorphisms in TLR4 and the pertussis toxin-specific immunoglobulin G response after whole-cell pertussis (wP) vaccination in 515 1-year-old children from the KOALA study. A lower titer was associated with the minor allele of

  6. Feeding mink (Neovison vison) a protein-restricted diet during pregnancy induces higher birth weight and altered hepatic gene expression in the F2 offspring

    DEFF Research Database (Denmark)

    Matthiesen, Connie Marianne Frank; Blache, Dominique; Thomsen, Preben Dybdahl;

    2010-01-01

    Malnutrition during foetal life can induce modifications in the phenotype of an individual. The present study aimed to observe effects of low foetal life protein provision on modifications of the phenotype and changes in the progeny of 1-year-old female mink (F1 generation) offspring of mothers f...

  7. Cow's milk and children

    Science.gov (United States)

    Milk and children; Cow’s milk allergy - children; Lactose intolerance - children ... You may have heard that cow's milk should not be given to babies younger than 1 year old. This is because cow's milk doesn't provide enough of certain ...

  8. 50 CFR 648.5 - Operator permits.

    Science.gov (United States)

    2010-10-01

    ...: Name, mailing address, and telephone number; date of birth; hair color; eye color; height; weight; and signature of the applicant. The applicant must also provide two recent (no more than 1 year old), color..., that, if the permit is suspended or revoked pursuant to 15 CFR part 904, the operator cannot be...

  9. 数字解读(英文)

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    74.1 Years Old A reporter with Xinhua News Agency recently obtained information,from the Office of the National Working Committee on Children and Women,which indicated the average life expectancy of Chinese women has risen from 73.3 years,in 2000,to the current 74.1 years.

  10. Digital Childhood

    Institute of Scientific and Technical Information of China (English)

    Wang Hairong

    2012-01-01

    Three-year-old Li Ming is a restless boy in Beijing,but one thing that always calms him down is an iPad.Like many young children in China,Li has been exposed to electronic products almost from birth.When he was about 1 year old,his mother began showing him animated children's songs on a computer.

  11. Bypass flow and its role in leaching of raised beds under different land use types on an acid sulphate soil.

    NARCIS (Netherlands)

    Minh, L.Q.; Tuong, T.P.; Booltink, H.W.G.; Mensvoort, van M.E.F.; Bouma, J.

    1997-01-01

    A better understanding of leaching processes in raised beds is useful in assessing management options for acid sulphate soils. Field and laboratory studies were carried out to quantify the effects of soil physical properties and bypass flow on leaching processes of new, 1-year-old and 2-year-old rai

  12. CARDIAC AND BEHAVIORAL-RESPONSES OF LONG-TERM OBESE AND LEAN ZUCKER RATS TO EMOTIONAL-STRESS

    NARCIS (Netherlands)

    NYAKAS, C; BALKAN, B; STEFFENS, AB; BOHUS, B

    1995-01-01

    Obesity is known as a risk factor in stress-related cardiovascular pathology in man. The length of obesity can be an important interacting variable. Therefore, cardiac and behavioral responses to emotional stress were studied in 1-year-old, genetically obese (fa/fa) and lean (Fa/-) male Zucker rats,

  13. Prevenção de anemia no primeiro ano de vida em centros de saúde do município de Santo André, São Paulo

    DEFF Research Database (Denmark)

    Szarfarc, S C; Berg, Gabriele; Santos, A L;

    1996-01-01

    The aim of this study was to evaluate the efficacy of an iron prophylactic supplementation program, in three health centers of Santo André, in São Paulo state. The prevalence of anemia was identified in a control group consisting of 201 children of 1 year old. The intervention group consisted of ...

  14. Element repertoire: change and development with age in Whitethroat Sylvia communis song

    DEFF Research Database (Denmark)

    Balsby, T.J.S.; Hansen, P.

    2010-01-01

    Song repertoires are often important determining factors in sexual selection. In several species, older males have larger repertoires than 1-year-old males. The development of large song repertoires by an individual is, however, poorly understood. We studied song element repertoire changes in fiv...

  15. Efeito analgésico de antagonistas do receptor da histamina H1 em modelo de dor provocada por formalina em ratos Efecto analgésico de antagonistas del receptor de la histamina H1 en un modelo de dolor provocado por formalina en ratones Analgesic effects of H1 receptor antagonists in the rat model of formalin-induced pain

    Directory of Open Access Journals (Sweden)

    Hazem Adel Ashmawi

    2009-08-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Os receptores de histamina mediam vias nociceptivas principalmente no sistema nervoso central. Alguns estudos mostraram efeito analgésico de antagonistas de receptor de histamina no sistema nervoso periférico. Não está claro se o efeito analgésico local é classe específico ou droga específico. MÉTODO: Para responder a essa questão, utilizamos três diferentes antagonistas do receptor H1 (pirilamina, prometazina e cetirizina administrados diretamente na pata do rato, pela via intraperitoneal ou por bloqueio de nervo periférico em modelo de dor induzida por formalina. Observamos o efeito das drogas no comportamento do número de elevações da pata. RESULTADOS: Na fase I, a pirilamina local diminuiu o número de elevações da pata de forma dose-dependente. Na dose mais alta, a diminuição foi de 97,8%. Para a prometazina, a diminuição foi de 92% e para cetizirina, 23,9%. Na fase II, a pirilamina diminuiu o número de elevações da pata em 93,5%, a prometazina em 78,2% e a cetirizina em 80,1%. A administração dos fármacos por via intraperitoneal não alterou o comportamento doloroso. Quando utilizadas para bloqueio de nervo periférico, na fase I, a pirilamina diminuiu o número de elevações da pata em 96,7%, a prometazina em 73,3% e a cetirizina em 23,9%. Na fase II, a pirilamina levou à diminuição de 86,6%, a prometazina de 64,4% e a cetirizina de 19,9%. CONCLUSÕES: Os resultados mostraram que os antagonistas de receptor da histamina H1 apresentam efeitos analgésicos locais, diferentes do efeito sistêmico, sendo um deles anti-inflamatório e classe específico e o outro específico para prometazina e pirilamina, semelhante a efeito clínico anestésico local.JUSTIFICATIVA Y OBJETIVOS: Los receptores de histamina intermedian las vías nociceptivas, principalmente en el sistema nervioso central. Algunos estudios arrojaron un efecto analgésico de antagonistas de receptor de histamina en el

  16. Psicopatía, violencia y criminalidad: un análisis psicológico-forense, psiquiátrico-legal y criminológico (Parte I Psychopathy, violence and crime: a psychological-forensic, psychiatric-legal and criminological analysis (Part I

    Directory of Open Access Journals (Sweden)

    J.M. Pozueco Romero

    2011-09-01

    Full Text Available Tras más de 200 años de historia, el concepto de "psicopatía" ha venido experimentando una auténtica y variopinta metamorfosis terminológica. Exceptuando aquellos períodos del Medievo en los que se creía que la psicopatía y cualquier otra conducta y personalidad "anormales" eran bien de origen demoníaco, bien de corte estrictamente hereditarista-biologicista-fisionomista-antropométrico, el resto de enfoques teórico-investigadores han arrojado sobrada luz que, a día de hoy, y tras más de 200 años de historia amarga y controvertida sobre el término, nos permiten haber llegado a un consenso generalizado entre los estudiosos de la psicopatía desde el punto de vista clínico-forense y criminológico. Este primer trabajo o Parte I es una revisión en la que se pretende ahondar en los polémicos y muchas veces incomprobables orígenes del término "psicopatía". Por otro lado, y tras intensas investigaciones empíricas realizadas desde los años 70 y centradas fundamentalmente en la población penitenciaria, modernamente se ha comenzado a hablar, de manera distintiva, tanto de los psicópatas criminales como de los psicópatas integrados, habiéndose hallado que la diferencia principal entre ambos tipos de psicópatas estriba, sencillamente, en la concreta comisión de delitos, puesto que la estructura básica de personalidad es prácticamente la misma en ambos tipos de psicópatas. Finalmente, se hace muy necesario subrayar que el carácter antisocial de la personalidad y conducta se observa, por definición, en cualquier tipo de delincuentes, sean éstos o no psicópatas, un carácter antisocial que, por otro lado, no siempre ni necesariamente se observa entre los denominados psicópatas integrados.After more than 200 years of history, the concept of "psychopathy" has been undergoing an authentic and varied terminological metamorphosis. Except for those periods in the Medieval Age in which it was believed that psychopathy and other

  17. Efeito analgésico de longa duração da dipirona sobre a hiperalgesia persistente induzida pela constrição do nervo ciático em ratos: participação do óxido nítrico Long term analgesic effect of dipyrone on the persistent hyperalgesia induced by chronic constriction injury of sciatic nerve in rats: involviment of nitric oxide

    Directory of Open Access Journals (Sweden)

    Fábio José Reis

    2006-12-01

    Full Text Available O efeito analgésico de longa duração da dipirona foi avaliado em um modelo de dor neuropática assim como a participação da via óxido nítrico-GMPc neste mecanismo analgésico. Uma única administração intraplantar de dipirona (80 µg, no 14º dia após a instalação da hiperalgesia neuropática induzida pela constrição do nervo ciático exerceu um efeito analgésico, significativo e de longa duração. A inibição da óxido nítrico sintetase com L-NAME (50 ou 100 µg/pata, ou do óxido nítrico (NO endógeno com hemoglobina (10 ou 30 µg/pata, bloquearam o desenvolvimento do efeito analgésico da dipirona. A L-arginina (500 µg/pata reverteu o efeito do L-NAME. Cloreto de metiltionínio (azul de metileno (500 µg/pata, ODQ (50 µg/pata (bloqueadores da guanilil ciclase ou glibenclamida (100, 200 ou 300 µg/pata (bloqueador de canais de K+ sensíveis ao ATP inibiram o efeito analgésico da dipirona. O nitroprussiato de sódio administrado no 14º dia após a instalação da hiperalgesia neuropática também exerceu efeito analgésico de longa duração, semelhante ao observado com a dipirona. Sugerimos que a ação analgésica periférica e de longa duração da dipirona, neste modelo experimental, ocorra devido a provável dessensibilização dos nociceptores, envolvendo a via óxido nítrico - GMPc e canais de K+ sensíveis ao ATP.The long term analgesic effect of dipyrone was evaluated on a model of neuropathic pain and the role of nitric oxide/GMPc pathway in this antinociceptive mechanism. One intraplantar dipyrone administration (80 mg, at 14th day after the chronic constriction injury of the sciatic nerve, induced a significant and long term analgesic effect. The inhibition of nitric oxide synthase (NOS with L-NAME (50 or 100 mg/paw or scavenging of the endogenous NO with hemoglobin (10 or 30 mg/paw inhibited the development of the dipyrone analgesia. L-arginine (500 mg/paw could reverted the effect of L-NAME. Metylene blue

  18. Using an experimental model for the study of therapeutic touch Uso de un modelo experimental para estudio sobre el toque terapéutico Utilização de um modelo experimental para estudo sobre o toque terapêutico

    Directory of Open Access Journals (Sweden)

    Daniella Soares dos Santos

    2013-02-01

    Full Text Available OBJECTIVE: to verify whether the Paw Edema Model can be used in investigations about the effects of Therapeutic Touch on inflammation by measuring the variables pain, edema and neutrophil migration. METHOD: this is a pilot and experimental study, involving ten male mice of the same genetic strain and divided into experimental and control group, submitted to the chemical induction of local inflammation in the right back paw. The experimental group received a daily administration of Therapeutic Touch for 15 minutes during three days. RESULTS: the data showed statistically significant differences in the nociceptive threshold and in the paw circumference of the animals from the experimental group on the second day of the experiment. CONCLUSION: the experiment model involving animals can contribute to study the effects of Therapeutic Touch on inflammation, and adjustments are suggested in the treatment duration, number of sessions and experiment duration.OBJETIVO: verificar si el Modelo de Edema de Pata puede ser utilizado en las investigaciones acerca de los efectos del Toque Terapéutico sobre la inflamación, mensurándose las variables dolor, edema y migración de neutrófilos. MÉTODO: se trata de un estudio piloto, experimental, con 10 ratones machos del mismo linaje genético, divididos en grupo experimental y control, sometidos a inducción química de inflamación local en la pata derecha trasera. O grupo experimental recibió una aplicación diaria de Toque Terapéutico con duración de quince minutos, por tres días. RESULTADOS: Los datos evidenciaron diferencias estadísticamente significativas en el umbral de nocicepción y circunferencia de las patas de los animales del grupo experimental durante el segundo día del experimento. CONCLUSIÓN: El modelo de experimento con animal puede contribuir al estudio de los efectos del Toque Terapéutico sobre la inflamación: se sugiere ajuste en el tiempo de exposición, número de sesiones y

  19. Evaluation of averted doses to infants by tap water restrictions after the Fukushima Daiichi nuclear power plant accident

    International Nuclear Information System (INIS)

    There has been some concern in reviewing the effectiveness of making decisions on the implementation of protective measures in emergency exposure situations. After the Fukushima Daiichi nuclear power plant accident, temporal changes in the concentration of iodine 131 in tap water were studied using published data from several authorities in Fukushima, Ibaraki, and Tokyo. Averted doses to infants (1-year-old children) due to the intake of iodine 131 through tap water restrictions were also evaluated. Consequently, it was found that the apparent half-life of iodine 131 in tap water was 2.8 days. The averted equivalent doses to the thyroids of 1-year-old children were found to have a maximum value of 8.3 mSv in a local area of Fukushima. Hence, the tap water restrictions implemented by the authorities were considered to be effective in the early phase of the emergency exposure situation. (author)

  20. Efeito do meloxicam sobre a lesão de isquemia e reperfusão em músculo esquelético de ratos Effect of meloxicam on ischemia-reperfusion injury in skeletal muscle of rats

    Directory of Open Access Journals (Sweden)

    Vitor A. Uhle

    2000-01-01

    Full Text Available Os antiinflamatórios não esteroidais, derivados do piroxicam, agem como varredores de radicais livres de oxigênio em experimentos in vitro. O objetivo deste trabalho foi analisar o efeito do meloxicam em músculos esqueléticos de ratos submetidos à isquemia e reperfusão com base na análise de liberação de malondialdeído da membrana celular ( indicador de peroxidação lipídica provocada pelos radicais livres. Dezoito ratos Wistar foram divididos em 2 grupos de 9. O grupo I (grupo sham foi tratado previamente com 3g/kg de peso de solução fisiológica e o grupo II com 3g/kg de peso de meloxicam por via peritoneal. Após 5 min os ratos foram submetidos a 3h de isquemia total ( torniquete e 45 min de reperfusão das patas posteriores esquerdas. Colheram-se biópsias dos músculos isquêmicos e reperfundidos e das patas controles (contralaterais para a dosagem de malondialdeído. A análise das diferenças de concentração do malondiadeído nas patas controles e reperfundidas no grupo I (43,7± 60,7; n=9 em relação ao grupo II (21,7± 49,5; n=9 não mostrou alteração significante (p=0,3. Os dados obtidos, neste trabalho, mostram que o meloxicam não protege a musculatura esquelética dos danos causados pela isquemia e reperfusão, com base na análise do malondialdeído tissular após 3h de isquemia e 45 min de reperfusão.

  1. Lymphedema secondary to filariasis

    Energy Technology Data Exchange (ETDEWEB)

    Leonard, J.C.; Humphrey, G.B.; Basmadjian, G.

    1985-03-01

    A 1-year-old immunodeficient boy developed brawny edema of the left foot. Lymphoscintigraphy revealed no evidence of left inguinal activity following pedal injection of Tc-99m-Sn phosphate. Over the next two months, the patient developed lymphedema on the right and repeat scintigraphy demonstrated no movement of isotope from the dorsum of either foot. Subsequent studies identified microfilaria in a nocturnal blood smear, which were thought to represent Brugia beaveri acquired by mosquito transmission in Oklahoma.

  2. Femoral kontroll blant idrettsaktive kvinner : testutvikling og sammenheng med skadehistorikk

    OpenAIRE

    Østvold, Mattis

    2011-01-01

    Purpose: Non-contact knee injuries are often the topic of discussion in relation to injury prevention. The purpose of this study was to develop a standardized test and a standardized analysis method for quantifying changes in the femoral control in a simple but reliable way. We also wanted to quantify the relationship between femoral control and injury history in the sample. Method: Female athletes (n = 95, age = 18 ± 1 years old) who were active in various sports, conducted two weak links...

  3. Photosynthetic capacity and nitrogen partitioning in foliage of the evergreen shrub Daphniphyllum humile along a natural light gradient.

    Science.gov (United States)

    Katahata, Shin-Ichiro; Naramoto, Masaaki; Kakubari, Yoshitaka; Mukai, Yazuru

    2007-02-01

    We examined the effects of leaf age and mutual shading on the morphology, photosynthetic properties and nitrogen (N) allocation of foliage of an evergreen understory shrub, Daphniphyllum humile Maxim, growing along a natural light gradient in a deciduous Fagus crenata-dominated forest in Japan. Seedlings in high-light environments were subject to greater mutual shading and 1-year-old foliage survival was lower than in seedlings in low-light environments, indicating that the survival rates of foliage were related to the degree of mutual shading. Although specific leaf area (SLA) in current- and 1-year-old foliage was curvilinearly related to daily photosynthetic photon flux (PPF), SLA was unaffected by leaf age, indicating that foliage in D. humile may not acclimate morphologically to annual changes in light caused by mutual shading. Light-saturated net photosynthetic rates (Pmax) were correlated with daily PPF in current-year foliage. In addition, a strong, positive relationship was found between nitrogen concentration per unit leaf area and Pmax. In contrast, the relationship among PPF, N and photosynthetic parameters in 1-year old foliage was weak because of the strong remobilization of N from older leaves to current-year foliage in plants growing in high light. However, the relationship between daily PPF and both photosynthetic N-use efficiency and the ratio of maximum electron transport rate to maximum carboxylation rate did not differ between current-year and 1-year-old foliage, suggesting that these responses help maintain a high photosynthetic efficiency even in older foliage. We conclude that D. humile maximizes whole-plant carbon gain by maintaining a balance among photosynthetic functions across wide ranges of leaf ages and light environments.

  4. Lesch-Nyhan Syndrome: a rare disorder of self-mutilating behavior

    Directory of Open Access Journals (Sweden)

    Mrinal Gupta

    2014-01-01

    Full Text Available This paper describes Lesch-Nyhan syndrome in a 1-year-old boy. This X-linked recessive error of purine metabolism presents in infancy with a constellation of mental and developmental retardation, self-mutilating behavior, neurological features and abnormal urine uric acid: creatinine ratio. The basic defect is deficiency in phosphoribosyl transferase production but exact pathomechanism for clinical symptomatology remains un-elucidated. No specific medical treatment is available.

  5. Report on 1Y and 6M child models

    NARCIS (Netherlands)

    Meyer, F.; Deck, C.; Rodarius, C.; Meijer, R.; Yang, J.

    2011-01-01

    This document is the deliverable D.2.3.2 of the CASPER project. It has been done in the framework of WP2 “Child human body modeling” task 2.3 “Develop specific human segments and whole body models per age”. This task aims to provide the meshing of the whole body models of the 1 year old child (1 Y.O

  6. PMCV and PRV occurrence in wild and farmed fish in Denmark

    DEFF Research Database (Denmark)

    Mikkelsen, Susie Sommer; Arnö, J.; Bruun, Morten Sichlau

    Every year salmon are restocked in the 7 rivers Storå, Skjern Å, Varde Å, Sneum Å, Kongeå, Ribe Å and Gudenåen. Six-month-old and 1-year-old salmon for about 2 mio. Kr (€268000) are restocked every year. The salmon are restocked in both the main rivers as well as the larger inlets. 6-month-old sa...

  7. Age and Diet Affect Gene Expression Profile in Canine Skeletal Muscle

    OpenAIRE

    Middelbos, Ingmar S.; Brittany M Vester; Lisa K Karr-Lilienthal; Schook, Lawrence B; Swanson, Kelly S.

    2009-01-01

    We evaluated gene transcription in canine skeletal muscle (biceps femoris) using microarray analysis to identify effects of age and diet on gene expression. Twelve female beagles were used (six 1-year olds and six 12-year olds) and they were fed one of two experimental diets for 12 months. One diet contained primarily plant-based protein sources (PPB), whereas the second diet contained primarily animal-based protein sources (APB). Affymetrix GeneChip Canine Genome Arrays were used to hybridiz...

  8. Infant Cardiac CT Angiography with 64-Slice and 256-Slice CT: Comparison of Radiation Dose and Image Quality Using a Pediatric Phantom

    OpenAIRE

    Lee, Yi-Wei; Yang, Ching-Ching; Mok, Greta S. P.; Wu, Tung-Hsin

    2012-01-01

    Background The aims of this study were to investigate the image quality and radiation exposure of pediatric protocols for cardiac CT angiography (CTA) in infants under one year of age. Methodology/Principal Findings Cardiac CTA examinations were performed using an anthropomorphic phantom representing a 1-year-old child scanned with non-electrocardiogram-gated (NG), retrospectively electrocardiogram-gated helical (RGH) and prospectively electrocardiogram-gated axial (PGA) techniques in 64-slic...

  9. Marginalia no. 21

    OpenAIRE

    Library, Merrill-Cazier

    2006-01-01

    Issue Number 21: Autumn 2006 “AS THE LIBRARY SHAPES STUDENTS, STUDENTS SHAPE THE LIBRARY”-A message from Director, Linda Wolcott LET US EAT CAKE! MERRILL-CAZIER LIBRARY IS 1-YEAR OLD!-The Library holds a birthday party. IDEAS IN FLIGHT-Patrick Williams on a popular birdhouse exhibit by Darrin Brooks Interior Design students. BOOKS STUDIO EXHIBIT: BASIC BINDING & BEYOND-Dennise Gackstetter describes unique book as art exhibit MORE GALLERY SPACE: FOR STUDENT EXHIBITS- A LOT MORE ...

  10. Understanding Attention: 12- and 18-Month-Olds Know What Is New for Other Persons.

    Science.gov (United States)

    Tomasello, Michael; Haberl, Katharina

    2003-01-01

    Twelve- and 18-month-olds played with 2 adults and 2 new toys. For a third toy, one adult left the room while the child and other adult played with it. This adult returned, looked at the 3 toys, expressed excitement, and asked "Can you give it to me?" Infants at both ages were able to do so, suggesting that 1-year-olds understand other persons as…

  11. Outcomes of a Clinic-Based Pediatric Constraint-Induced Movement Therapy Program

    Science.gov (United States)

    Reidy, Teressa Garcia; Naber, Erin; Viguers, Emily; Allison, Kristen; Brady, Kathleen; Carney, Joan; Salorio, Cynthia; Pidcock, Frank

    2012-01-01

    A single-group pre- and post-test design was used to evaluate functional outcomes of a constraint-induced movement therapy (CIMT) protocol implemented in an outpatient therapy center. The participants were 29 children with hemiplegia, ages 1.6-19.1 years old. The less-involved upper limb was placed in a cast that was worn 24 hr a day, 7 days a…

  12. Lymphedema secondary to filariasis

    International Nuclear Information System (INIS)

    A 1-year-old immunodeficient boy developed brawny edema of the left foot. Lymphoscintigraphy revealed no evidence of left inguinal activity following pedal injection of Tc-99m-Sn phosphate. Over the next two months, the patient developed lymphedema on the right and repeat scintigraphy demonstrated no movement of isotope from the dorsum of either foot. Subsequent studies identified microfilaria in a nocturnal blood smear, which were thought to represent Brugia beaveri acquired by mosquito transmission in Oklahoma

  13. Changes in Phytochemical Synthesis, Chalcone Synthase Activity and Pharmaceutical Qualities of Sabah Snake Grass (Clinacanthus nutans L.) in Relation to Plant Age

    OpenAIRE

    Ali Ghasemzadeh; Alireza Nasiri; Jaafar, Hawa Z. E.; Ali Baghdadi; Izham Ahmad

    2014-01-01

    In the current study, changes in secondary metabolite synthesis and the pharmaceutical quality of sabah snake grass leaves and buds were considered in relation to plant age (1 month, 6 months, and 1 year old). The activity of the enzyme chalcone synthase (CHS, EC 2.3.1.74) was measured, as it is a key enzyme for flavonoid production. Significant differences in total flavonoid (TF) production were observed between the three plant growth periods and the different plant parts. The highest conten...

  14. Raine syndrome: expanding the radiological spectrum

    Energy Technology Data Exchange (ETDEWEB)

    Koob, Meriam; Dietemann, Jean-Louis [CHU de Strasbourg Hopital de Hautepierre, Service de Radiologie 2, Strasbourg (France); Doray, Berenice; Fradin, Melanie [CHU de Strasbourg, Hopital de Hautepierre, Laboratoire de Genetique Medicale, Strasbourg (France); Astruc, Dominique [CHU de Strasbourg Hopital de Hautepierre, Service de Neonatologie, Strasbourg (France)

    2011-03-15

    We describe ante- and postnatal imaging of a 1-year-old otherwise healthy girl with Raine syndrome. She presented with neonatal respiratory distress related to a pyriform aperture stenosis, which was diagnosed on CT. Signs of chondrodysplasia punctata, sagittal vertebral clefting and intervertebral disc and renal calcifications were also found on imaging. This new case confirms that Raine syndrome is not always lethal. The overlapping imaging signs with chondrodysplasia punctata and the disseminated calcifications give new insights into its pathophysiology. (orig.)

  15. Adjuvanted poly(lactic-co-glycolic acid nanoparticle-entrapped inactivated porcine reproductive and respiratory syndrome virus vaccine elicits cross-protective immune response in pigs [Corrigendum

    Directory of Open Access Journals (Sweden)

    Binjawadagi B

    2014-05-01

    Full Text Available Binjawadagi B, Dwivedi V, Manickam C, et al. Int J Nanomedicine. 2014;9:679–694.Note that Figure 1B on page 684 contained an incorrect key. The correct key description should be interchanged, with 2-week-old NP-KAg for open circles, and 1-year-old NP-KAg for closed circles.Read the original article

  16. Informe de nuevas variedades IT-2004: NUEVA VARIEDAD DE TABACO NEGRO CUBANO (Nicotiana tabacum L.

    Directory of Open Access Journals (Sweden)

    E. Espino

    2005-01-01

    Full Text Available La nueva variedad de tabaco negro cubana 'IT-2004' posee un potencial de rendimiento de 2370 kg.ha-1 (700 qq/cab., con 20-22 hojas aprovechables por planta, es altamente resistente al moho azul, la pata prieta y necrosis ambiental y resistente a la sequía. Su calidad organoléptica responde al patrón del tabaco negro cubano, aunque con una fortaleza media, de ligera a medianamente fuerte, lo que permite su utilización como productora de materia prima para la industria cigarrera nacional.

  17. Esquemas cognitivos en personas con conducta de juego patológico y su relación con experiencias de crianza

    OpenAIRE

    Ana Estévez; Esther Calvete

    2007-01-01

    Este estudio evaluó si las personas con juego patológico presentaban esquemas negativos disfuncionales y recordaban estilos de crianza negativos en sus padres y madres durante su infancia. Participó una muestra de 167 ludópatas (77,2% hombres y 22,8% mujeres) y un grupo de contraste de 167 personas sin ludopatía (71,1% hombres y 28,9% mujeres). Se obtuvieron medidas de esquemas cognitivos negativos y de estilos parentales. Los resultados mostraron que las personas con juego patológico puntuab...

  18. Diseño y control reactivo de robots caminantes sobre terreno natural

    OpenAIRE

    Nabulsi Abussaid, Samir

    2008-01-01

    En las últimas décadas se ha constatado el creciente interés que presentan los robots caminantes, tanto desde el punto de vista de la investigación básica como de sus potenciales aplicaciones. Una de las principales características de los robots equipados con patas es su capacidad para poder desplazarse sobre una amplia variedad de terrenos no estructurados. Esta particularidad los hace muy atractivos e interesantes para su aplicación práctica como robots de servicios en los que se requiere l...

  19. Efecto de melatonina exógena en procesos inflamatorios agudos y crónicos en ratas

    OpenAIRE

    Rocha, Nadir de la; Rotelli, Alejandra Ester; Pelzer, Lilian

    2002-01-01

    Se investigó la influencia de melatonina (4 mg/kg) en la inflamación aguda usando el modelo de edema de pata en rata y en la inflamación crónica mediante la prueba del granuloma y artritis inducida por adyuvante. Melatonina inhibió el edema producido por carragenina en el modelo agudo, pero no presentó acción inhibitoria en la fase proliferativa de la prueba del granuloma y en la fase aguda y crónica de la artritis inducida por adyuvante. Estos resultados sugieren que melatonina, a la m...

  20. Grupos de Discusión y HJ-Biplot: Una Nueva Forma de Análisis Textual

    OpenAIRE

    Daniel Caballero Julia; Purificación Vicente Galindo; Mª Purificación Galindo Villardón

    2014-01-01

    Este trabajo da un paso más allá en la integración de métodos cualitativos de investigación y técnicas cuantitativas analizando Grupos de Discusión desde una perspectiva multivariante con el apoyo del HJ-Biplot. Una propuesta metodológica que combina la codificación cualitativa con un nuevo valor matemático de caracterización. La propuesta se aplica al estudio de las representaciones en el discurso sobre Calidad de Vida de los ludópatas.

  1. A new species of Caenis (Ephemeroptera: Caenidae) from Colombia

    OpenAIRE

    Molineri, Carlos

    2009-01-01

    La nueva especie Caenis tarapoto es descripta a partir de imagos machos colectados en la región Amazónica de Colombia. Esta nueva especie se caracteriza por una coloración general castaña oscura, triángulo prosternal aguzado anteriormente, patas anteriores 0.7-0.9 veces la longitud del cuerpo, forceps aguzados en el ápice, esclerito central de la placa estilígera elongado, penes con margen posterior suavemente convexo y con lóbulos peneanos completamente fusionados y proyectados lateralmente....

  2. Estado da arte de Bauhinia forficata Link (Fabaceae) como alternativa terapêutica para o tratamento do Diabetes mellitus

    OpenAIRE

    Graziella Silvestre Marques; Larissa Araújo Rolim; Lariza Darlene Santos Alves; Caio César de Andrade Rodrigues Silva; Luiz Alberto Lira Soares; Pedro José Rolim-Neto

    2013-01-01

    O Diabetes mellitus, por tratar-se de uma doença crônica e por apresentar um crescimento acentuado na sociedade brasileira, tornou-se alvo da comunidade científica na busca de novas alternativas terapêuticas. Diversos estudos estão sendo desenvolvidos com o objetivo de comprovar as aparentes propriedades farmacológicas de espécies vegetais empregadas no tratamento desta enfermidade. Sendo assim, a Bauhinia forficata Link, comumente conhecida como pata-de-vaca, figur...

  3. Relation between phylogeny of African green monkey CD4 genes and their respective simian immunodeficiency virus genes

    DEFF Research Database (Denmark)

    Fomsgaard, Anders; Müller-Trutwin, Michaela C.; Diop, Ousmane;

    1997-01-01

    An apparent species-specific relatedness of SIVagm suggests a coevolution with their natural hosts. However, the exact species or subspecies classification of African green monkeys, AGM, is uncertain because current classification schemes rely on phenotype markers, while more definitive genetic...... data are lacking. In this study, the CD4 protein involved in tissue type recognition was gentically cloned and sequence from PBMC RNA from all AGM species, including Barbados green monkeys (BGM). Phylogenetic trees were constructed that also included genomic CD4 nucleotide sequences from patas, sooty...

  4. COMPOSICIÓN QUIMICA DE LA LECHE, DIGESTIBILIDAD in vitro DE LA MATERIA SECA Y PRODUCCIÓN EN VACAS ALIMENTADAS CON GRAMÍNEAS SOLAS O ASOCIADAS CON Lotus uliginosus

    Directory of Open Access Journals (Sweden)

    A. Morales

    2013-01-01

    Full Text Available La presente investigación tuvo como objetivo evaluar el uso de la leguminosa Lotus uliginosus como alternativa de inclusión dentro de las praderas en dos ecorregiones estratégicas de la sabana de Bogotá. en cada finca se evaluaron cuatro tratamientos: 1 kikuyo solo (P. clandestinum, 2 kikuyo asociado con trébol pata de pájaro ( P.clandes-tinum + L. uliginosus, 3 festuca alta sola (F. arundinacea y 4 Festuca alta asociada con trébol pata de pájaro (F. arundinacea + L. uliginosus. el número de bovinos varió de acuerdo a la capacidad de carga de cada finca. se utilizaron animales que se encontraban en el segundo tercio de lactancia durante un período experimental de siete días. en cada tratamiento se determinó la producción (L/día y calidad de leche (% de grasa, proteína y sólidos totales; en la pastura se evaluó la composición química (Ms, Fdn, Fda y la digestibilidad in vitro de la materia seca (divMs. se midió el consumo voluntario. en la finca Megaleche la producción de biomasa presentó diferencias significativas (P<0,05 entre los tratamientos destacándose el tratamiento del kikuyo solo; la calidad nutricional de las pasturas también presentó diferencias (P<0,04 destacándose el tratamiento de kikuyo + trébol pata de pájaro, asociación que también se destacó en consumo voluntario (P< 0.05 y producción de leche (P<0,05. en la finca Colega el contenido de proteína del forraje presentó diferencias cuando las gramíneas se asociaron con el trébol pata de pájaro (P<0,001. se concluyó que la introducción del Lotus en las praderas mejoró la producción de leche y consumo de materia seca en los animales.

  5. Free Completely Random Measures

    CERN Document Server

    Collet, Francesca

    2011-01-01

    Free probability is a noncommutative probability theory introduced by Voiculescu where the concept of independence of classical probability is replaced by the concept of freeness. An important connection between free and classical infinitely divisibility was established by Bercovici and Pata (1999) in form of a bijection, mapping the class of classical infinitely divisible laws into the class of free infinitely divisible laws. A particular class of infinitely divisible laws are the completely random measures introduced by Kingman (1967). In this paper, a free analogous of completely random measures is introduced and, a free Poisson process characterization is provided as well as a representation through a free cumulant transform. Furthermore, some examples are displayed.

  6. A new species of Caenis (Ephemeroptera: Caenidae from Colombia

    Directory of Open Access Journals (Sweden)

    Carlos MOLINERI

    2009-01-01

    Full Text Available La nueva especie Caenis tarapoto es descripta a partir de imagos machos colectados en la región Amazónica de Colombia. Esta nueva especie se caracteriza por una coloración general castaña oscura, triángulo prosternal aguzado anteriormente, patas anteriores 0.7-0.9 veces la longitud del cuerpo, forceps aguzados en el ápice, esclerito central de la placa estilígera elongado, penes con margen posterior suavemente convexo y con lóbulos peneanos completamente fusionados y proyectados lateralmente.

  7. Clásicos de la Psiquiatría Española del Siglo XIX: Emilio P¡ y Molist.

    Directory of Open Access Journals (Sweden)

    Antonio M Rey González

    1983-01-01

    Full Text Available Evocamos, en esta ocasión, la vida y la obra del ilustre frenópata catalán D. Emilio PI y MOL1ST, figura central, junto con GINE y PARTAGAS, de la psiquiatría española del siglo XIX. Ambos convirtieron a Barcelona en la sede central de la especialidad, que más tarde pasaría a Madrid, aunque sin alcanzar el esplendor logrado en esta etapa de florecimiento catalán

  8. Efecto de la edad, el sexo y el tiempo en la biometría del Piquituerto común (Loxia curvirostra curvirostra) en Navarra = Effect of age, sex and time in the biometrics of common crossbill (Loxia curvirostra curvirostra) in Navarre.

    OpenAIRE

    D. Alonso, J. Arizaga

    2005-01-01

    Se estudia en detalle la biometría del Piquituerto Común (Loxia curvirostra curvirostra) en Navarra (N de España, W de Pirineos), según los sexos, edad y el año de captura. entre 1994 y 2006 se capturaron un total de 2101 aves, en dos localidades emplazadas en bosques de pino silvestre (Pinus sylvestris). Además de la edad y sexo, en cada ejemplar se tomaron diez medidas, relacionadas con el ala, cola, pata y pico, y la morfología del ala de 2004 a 2006. Para toda variable hubo diferencias si...

  9. Japan, quality tourist destiny: a learner option for Colima

    OpenAIRE

    Irma Magaña Carrillo

    2007-01-01

    In this research feature presentation some results are presented as "A Propose Plan to implement a Culture with Quality Control in Tourism Business making Mexico an Attractive site in the Asia-Pacific market and Active within the PATA organism in the XXI Millennium". Which was performed in Japan from 2001 to 2004. This thesis acquires the category of qualitative and emergent and it arouse as a first attempt in reaching the point of a systematic application of the theory of the Model for Total...

  10. El anciano con cardiopatía terminal

    OpenAIRE

    Martínez Sellés Oliveria Soares, Manuel

    2009-01-01

    El objetivo de este documento es aportar un punto de vista experto que permita un mejor conocimiento de la situación y una mejora en el manejo y la toma de decisiones en los últimos días de vida del paciente de edad avanzada que sufre una cardiopatía. Los cardiópatas ancianos constituyen un grupo heterogéneo y es necesaria una valoración exhaustiva, especialmente de los factores que condicionan el pronóstico (cardiopatía, comorbilidad, situación funcional y datos de fragilidad) antes de tomar...

  11. Tratamiento quirúrgico de algunos trastornos mentales

    OpenAIRE

    Lourído-Albán, Francisco A.

    2012-01-01

    La mayoría de los autores están acordes en considerar la Leucotomía Profesional como reservada a los casos de mal pronóstico y como la última carta a jugar (Trelles), para tratar de curar algunos síntomas como el dolor mental, la ansiedad y la tensión angustiosa, con base en el sacrificio de la personalidad del individuo pues "la leucotomía mejora pero no transforma al psicópata en individuo normal" (Fleming). Según Reitman, la leucotomía pre-frontal provoca alteraciones regresivas de la pers...

  12. El concepto de "Constitución" en el Río de La Plata (1750-1850)

    OpenAIRE

    Noemí Goldman

    2007-01-01

    Este artículo estudia los cambios y permanencias en el significado del concepto de constitución en el Río de la Plata en un arco temporal de importantes cambios políticos. En sus particulares modulaciones semánticas, el concepto da cuenta del conflictivo proceso de revolución, guerras de independencia y disputas en torno al ejercicio y a la definición de la soberanía entre los pueblos que emergieron de la crisis de la Monarquía española de 1808. En efecto, el Río de la Pata ...

  13. Sobre realismo y montaje

    OpenAIRE

    Prada Perez De Azpeitia, Manuel

    2014-01-01

    Se suele pensar que los montajes del arte surgieron a principios del siglo XX de la mano de Picasso, los constructivistas, dadaístas y surrealistas, pero es fácil comprobar la existencia de montajes significativos en distintas épocas y culturas: historias contadas con imágenes yuxtapuestas, seres híbridos compuestos con partes de seres diferentes, objetos con piernas o patas de animal, lo cual permite sospechar que el montaje no es un modo reciente del arte, sino un modo original y universal ...

  14. Sobre realismo y montaje

    OpenAIRE

    Prada, Manuel

    2014-01-01

    Se suele pensar que los montajes del arte surgieron a principios del siglo xx de la mano de Picasso, los constructivistas, dadaístas y surrealistas, pero es fácil comprobar la existencia de montajes significativos en distintas épocas y culturas: historias contadas con imágenes yuxtapuestas, seres híbridos compuestos con partes de seres diferentes, objetos con piernas o patas de animal, lo cual permite sospechar que el montaje no es un modo reciente del arte, sino...

  15. Glucose metabolism in rats submitted to skeletal muscle denervation

    Directory of Open Access Journals (Sweden)

    Wilton Marlindo Santana Nunes

    2005-07-01

    Full Text Available This study analyzed the local and systemic effects of immobilization by denervation of the skeletal muscle on glucose metabolism. The rats were submitted to section of the right paw sciatic nerve. A reduction was observed in glucose uptake by the isolated soleus muscle of the denervated paw after 3 and 7 days, but not after 28 days in relation to the control animals. There was no difference after 3 and 7 days in glucose uptake by the soleus muscle of the opposite intact paw in relation to the control. There was increased glucose uptake in the same paw 28 days after denervation. The rate of glucose removal in response to exogenous insulin after 28 days of denervation was significantly higher than in control animals and those observed after 3 and 7 days of denervation. These results suggest that immobilization by denervation interfered not only in glucose metabolism in the skeletal muscle involved but also in other tissues.O estudo analisou os efeitos locais e sistêmicos da imobilização por desnervação do músculo esquelético sobre o metabolismo glicidico. Ratos foram submetidos à secção do nervo ciático da pata direita. Observou-se redução da captação de glicose pelo músculo sóleo isolado da pata desnervada após 3 e 7 mas não após 28 dias em relação a animais controle. Não houve diferença após 3 e 7 dias na captação de glicose pelo músculo sóleo da pata contralateral intacta em relação ao controle. Houve aumento da captação de glicose nesta mesma pata 28 dias após a desnervação. A taxa de remoção da glicose em resposta à insulina exógena após 28 dias de desnervação foi significantemente superior à do controle e àquelas observadas após 3 e 7 dias da desnervação. Esses resultados sugerem que a imobilização por desnervação interfere não só no metabolismo da glicose no músculo esquelético envolvido como também em outros tecidos.

  16. Caracterización comparativa a la faena de cinco híbridos experimentales de pollo campero con diferente genotipo materno

    OpenAIRE

    Dottavio, Ana María; Advínculo, S. A.; Librera, J. E.; Romera, Bernardo Martín; Canet, Zulma E.; Di Masso, Ricardo

    2014-01-01

    Se evaluaron la proporción de pechuga, pata muslo y grasa abdominal y el rendimiento a la faena de machos pertenecientes a cinco grupos genéticos experimentales de pollos camperos. Los grupos provenían del cruzamiento entre gallos de la población sintética paterna AH’, mejorada por tasa de crecimiento y eficiencia alimenticia y gallinas de cinco poblaciones sintéticas maternas. Como grupo testigo se utilizaron machos contemporáneos de la versión tradicional de Campero INTA. Las aves producto ...

  17. Post Mortem y Tony Manero

    OpenAIRE

    Urrutia, Carolina

    2015-01-01

    Post Mortem, el tercer largometraje de Pablo Larraín, podría ser el preludio de su cinta anterior Tony Manero ; el momento en que el protagonista (en ambas instancias interpretado por Alfredo Castro), cae irreversiblemente en la locura y se vuelve psicópata. La apuesta en ambos filmes es extrema porque asume la representación y la relectura de una época extrema, donde la demencia que se activa con el régimen militar ya parece estar instalada en la sociedad que lo origina y que ahora simplemen...

  18. SALINE WATER RESOURCES IN CLUJ-NAPOCA SURROUNDINGS

    OpenAIRE

    B. CZELLECZ; I. GÁBOR; L. RAVASZ; G. ȘCHIOPU; N. SZOPOS

    2016-01-01

    Saline waters are usually researched in those places where it is used for balneotherapy or other industrial purposes. The aim of this study is to describe the saline water sources from less known areas, as they are an important natural mineral water resource. Twenty nine water samples were analyzed from Cojocna-Pata-Sopor region, thirteen of them can be considered saline waters. The visited locations are 21, 15 and 3 km far from Cluj-Napoca. Highly concentrated springs are to be found in the ...

  19. Actividad antinociceptiva, anti-inflamatoria y relajante muscular de (+)-curcufenol aislado de la esponja marina didiscus oxeata

    OpenAIRE

    Salama, Ahmed; Toscano, Mariela; Del Valle, Martha; Vargas, Erika

    2008-01-01

    Mediante el método de edema plantar inducido por carragenina en la pata de la rata, (+)-curcufenol aislado de la esponja marina Didiscus oxeata mostró una actividad antiinflamatoria moderada, en las dosis de 100, 150 y 200 mg/kg administradas por vía oral, mientras que la actividad antinociceptiva fue confirmada por el método de contorsiones inducidas por ácido acético en ratones mostrando un efecto analgésico muy alto, en las dosis de 50, 100, 150 y 200 mg/kg administradas por vía oral, en c...

  20. Antocianinas em extratos vegetais: aplicação em titulação ácido-base e identificação via cromatografia líquida/espectrometria de massas

    Directory of Open Access Journals (Sweden)

    Wesson Guimarães

    2012-01-01

    Full Text Available Anthocyanins extracted from picao, quaresmeira, petunia, flamboyant, purple ipe, lobeira, pata de vaca, jaboticaba, purple cabbage and jambul were evaluated as natural acid-base indicators. Anthocyanins in extracts were identified using HPLC/MS. Clear, rapid change in color at final-point titration was observed for extracts but only picao showed strong change in pH. Indirect determination of carbonate in limestone using a natural indicator was performed and results compared with phenolphthalein indicator and potentiometer titration. Optimal results were obtained with picao but other extracts showed good accuracy and precision.

  1. Forma paraplégica de tétano associada a lesão medular pregressa

    Directory of Open Access Journals (Sweden)

    Roberto Melaragno

    1958-06-01

    Full Text Available Apresentação de um caso de forma paraplégica de tétano, com ponto de partida no pé, verificada em paciente portador de lesão medular pregressa (inflamatória? desmielinizante?. Os autores levantam a hipótese de que seu caso seria a reprodução, na patologia humana, das conclusões experimentais de Meyer, Ranson e outros, que conseguiram limitar o tétano aos membros posteriores de animais de laboratório quando, previamente à injeção de toxina na pata posterior, seccionavam a medula espinal.

  2. La globalización y su impacto en la economía de la educación en el sistema educativo público de Puerto Rico

    OpenAIRE

    Pizarro Figueroa, J.

    2010-01-01

    En este mundo globalizado la educación se constituye en un factor indispensable pata el crecimiento del ser humano y su sociedad. La educación es determinante para el crecimiento económico, social y ecológico de un país. En este ensayo presentamos un análisis sobre la economía de la educación. A tales fines, comenzaremos discutiendo el concepto de la globalización y sus características, tanto sus ventajas como desventajas. Posteriormente, analizaremos la economía de la educación en el Sistema...

  3. Influência da radiação por feixe de eletrões no perfil cromatográfico de Bauhinia variegata var candida: flor comestível proveniente do brasil

    OpenAIRE

    Heleno, Sandrina A.; Villavicencio, Anna L.C.H.; Barros, Lillian; Isabel C. F. R. Ferreira

    2016-01-01

    As flores de Bauhinia variegata var candida apresentam coloração branca e são vulgarmente conhecidas como “patas de vaca branca”, sendo muito utilizadas na cozinha gourmet como forma de aumentar a qualidade sensorial e nutricional dos alimentos [1,2]. No presente estudo, as flores foram submetidas a radiação por feixe de eletrões em diferentes doses (0,5 e 0,8 kGy) como forma de descontaminação, e seguidamente analisadas em termos de parâmetros nutricionais (humidade, proteí...

  4. Estudio del comportamiento térmico y la composición de aceites para el curtido de cueros

    Directory of Open Access Journals (Sweden)

    Grompone, M. A.

    2000-06-01

    Full Text Available The leather industry uses fatty materials to give leather certain characteristics. Neatsfoot oil, a material with variable cost and disponibility, has been used traditionally. Samples of neatsfoot, chicken, fish and rice bran oils are studied in this work. They are evaluated as potential raw materials for leather tanning derivatives, according to their thermal behaviour (Cold Test and DSC and main fatty acids composition (GC. Some seem adequate for that purpose, while others could be modified through thermal fractionation.La industria del cuero utiliza materiales grasos que otorgan determinadas características al cuero. Tradicionalmente se ha usado, entre otros, el aceite de patas de vacuno, producto cuya disponibilidad y costo son muy variables. En este trabajo se estudiaron muestras de distintos aceites de patas de vacuno, de pollo, de pescado y de salvado de arroz. Fueron evaluadas como potenciales materias primas para la obtención de derivados para el curtido de cueros, en función de su comportamiento térmico (“Cold Test” y DSC, y su composición en ácidos grasos principales (GC. Algunos de los aceites estudiados aparecen como adecuados para dicho uso, mientras que otros podrían ser mejorados por fraccionamiento térmico.

  5. Asymmetric processing of durational differences - electrophysiological investigations in Bengali.

    Science.gov (United States)

    Roberts, Adam C; Kotzor, Sandra; Wetterlin, Allison; Lahiri, Aditi

    2014-05-01

    Duration is used contrastively in many languages to distinguish word meaning (e.g. in Bengali, [pata] 'leaf' vs. [pat:a] 'whereabouts'). While there is a large body of research on other contrasts in speech perception (e.g. vowel contrasts and consonantal place features), little work has been done on how durational information is used in speech processing. In non-linguistic studies of low-level processing, such as visual and non-linguistic acoustic pop-out tasks, an asymmetry is found where additional information is more readily detected than missing information. In this study, event-related potentials were recorded during two cross-modal auditory-visual semantic priming studies, where nonword mispronunciations of spoken prime words were created by changing the duration of a medial consonant (real word [dana] 'seed'>nonword [dan:a]). N400 amplitudes showed an opposite asymmetric pattern of results, where increases in consonantal duration were tolerated and led to priming of the visual target, but decreases in consonantal duration were not accepted. This asymmetrical pattern of acceptability is attributed to the fact that a longer consonant includes all essential information for the recognition of the original word with a short medial consonant (a possible default category) and any additional information can be ignored. However, when a consonant is shortened, it lacks the required durational information to activate the word with the original long consonant. PMID:24726333

  6. Environmental Equity through Negotiation: A Case Study on Urban Landfills and the Roma Community

    Science.gov (United States)

    Petrescu-Mag, Ruxandra Mălina; Petrescu, Dacinia Crina; Oroian, Ioan Gheorghe; Safirescu, Ovidiu Călin; Bican-Brișan, Nicoleta

    2016-01-01

    The paper discusses the necessity to bring environmental equity within the Pata Rât Roma community in Northwest Romania, relying on the answers to three questions: “Does environmental equity exist in Pata Rât?”, “How can it be attained?”, and “To what extent can it be brought to the targeted people?” It was shown how a trio of factors tailors the destiny of Roma inhabitants: being a minority, their ethnicity, and the fact they are living on and off what society rejects and dumps—a landfill. The framing of the environmental equity concerns within a vision considering negotiation as the most adequate means to attain it is a novel approach. Further on, the results of the study can fuel win-win solutions in environmental equity. The information abstracted from a set of indicators, assessed through an evaluation matrix, represents a beneficial platform for future bottom-up decisions concerning landfill residents. Three action options were analyzed: on-site living opportunities—that resulted to be preferred, off-site living opportunities, and “Do nothing”. The analysis provides qualitative evidence that the evaluation of environmental equity is largely subjective, because of its complexity and specificity related to geographical, historical, cultural characteristics, and political interests. PMID:27314371

  7. Estudo preliminar da atividade antiinflamatória de Bryophillum calycinum Salisb Preliminar study of the anti-inflammatory activity of Bryophillum calycinum Salisb

    Directory of Open Access Journals (Sweden)

    P.J.C. Sousa

    2005-03-01

    Full Text Available Foram avaliados a toxicidade aguda (DL50 do Extrato Bruto Aquoso Liofilizado das folhas de Bryophillum calycinum Salisb. (EBALBc e seu efeito antiinflamatório sobre o edema de pata de rato induzido por carragenina e dextrana. Com a dose de 500 mg/kg (p.o inibiu o edema de pata induzido por dextrana de maneira significativa (p The acute toxicity (LD50 and the anti-inflammatory effect of the crude freeze-dried aqueous extract of the leaves of Bryophillumcalycinum Salisb. (EBALBc was evaluated, on the rat paw edema induced by carrageenin and dextran. The dose of 500 mg/kg (p.o inhibited the paw edema induced by dextran in a significative manner (p < 0.05, ANOVA, Student Newman-Keuls test 60 and 90 minutes, after stimulus while only the oral dose of 1 g/kg of EBALBc inhibited the paw edema induced by carrageenin. The results indicated an anti-edematogenic effect of the extract when tested on the paw edema induced by dextran and carrageenin, suggesting larger specificity of action on the edema induced by dextran. The EBALBc administered orally, in the doses of the 0.1 to 8 g/kg, it did not cause death, making impossible to determine the LD50.

  8. Environmental Equity through Negotiation: A Case Study on Urban Landfills and the Roma Community

    Directory of Open Access Journals (Sweden)

    Ruxandra Mălina Petrescu-Mag

    2016-06-01

    Full Text Available The paper discusses the necessity to bring environmental equity within the Pata Rât Roma community in Northwest Romania, relying on the answers to three questions: “Does environmental equity exist in Pata Rât?”, “How can it be attained?”, and “To what extent can it be brought to the targeted people?” It was shown how a trio of factors tailors the destiny of Roma inhabitants: being a minority, their ethnicity, and the fact they are living on and off what society rejects and dumps—a landfill. The framing of the environmental equity concerns within a vision considering negotiation as the most adequate means to attain it is a novel approach. Further on, the results of the study can fuel win-win solutions in environmental equity. The information abstracted from a set of indicators, assessed through an evaluation matrix, represents a beneficial platform for future bottom-up decisions concerning landfill residents. Three action options were analyzed: on-site living opportunities—that resulted to be preferred, off-site living opportunities, and “Do nothing”. The analysis provides qualitative evidence that the evaluation of environmental equity is largely subjective, because of its complexity and specificity related to geographical, historical, cultural characteristics, and political interests.

  9. Psicopatía, violencia y criminalidad: un análisis psicológico-forense, psiquiátrico-legal y criminológico (Parte II Psychopathy, violence and crime: a psychological-forensic, psychiatric-legal and criminological analysis (Part II

    Directory of Open Access Journals (Sweden)

    J.M. Pozueco Romero

    2011-12-01

    Full Text Available La Jurisprudencia española se encuentra frecuentemente ante dictámenes periciales en los que aparecen términos como psicópata, trastorno antisocial de la personalidad, personalidad psicopática, psicópata desalmado, psicopatía epileptoide, sociopatía, etc. De esta forma, no es infrecuente que los juristas (magistrados, jueces, fiscales, abogados se hallen desorientados ante tanta terminología que, pese a todo, en absoluto se constituyen en sinónimos. La Doctrina, por su parte, disiente de la visión tradicionalmente ya asentada en la Jurisprudencia de que los psicópatas sean sujetos inimputables. Muchos penalistas conocen bien los textos y estudios psicológicos y psiquiátricos que al respecto existen, y en ellos suelen basarse para establecer ciertas diferencias que aparentemente son sutiles. Una de las controversias más prolongadas es si los términos trastorno antisocial de la personalidad y psicopatía son la misma entidad. En la revisión de esta Parte II también se pretende ahondar en y remarcar esas sutiles diferencias, ya que se ha demostrado reiteradamente que ambas entidades diagnósticas, si bien comparten algunos rasgos en común, no son el mismo concepto ni comportan las mismas consecuencias. Asimismo, se analiza la enconada polémica que existe en torno a la frecuente asociación entre psicopatía y consumo de drogas, una polémica que parece sentar sus orígenes en esa misma confusión terminológica entre psicopatía y trastorno antisocial de la personalidad. Finalmente, se revisa la bibliografía relativa a la criminalidad de los psicópatas, haciendo especial referencia tanto al caso de los delincuentes comunes como al caso de los asesinos en serie y otros delincuentes violentos, sin perder de vista la posición que actualmente tienen los psicópatas a nivel penológico, doctrinal y jurisprudencial.Spanish jurisprudence is frequently faced with the fact that in some expert reports appear terms like psychopath

  10. Unravelling the importance of forest age stand and forest structure driving microbiological soil properties, enzymatic activities and soil nutrients content in Mediterranean Spanish black pine(Pinus nigra Ar. ssp. salzmannii) Forest.

    Science.gov (United States)

    Lucas-Borja, M E; Hedo, J; Cerdá, A; Candel-Pérez, D; Viñegla, B

    2016-08-15

    This study aimed to investigate the effects that stand age and forest structure have on microbiological soil properties, enzymatic activities and nutrient content. Thirty forest compartments were randomly selected at the Palancares y Agregados managed forest area (Spain), supporting forest stands of five ages; from 100 to 80years old to compartments with trees that were 19-1years old. Forest area ranging from 80 to 120years old and without forest intervention was selected as the control. We measured different soil enzymatic activities, soil respiration and nutrient content (P, K, Na, Mg, Cr, Mn, Fe, Co, Ni, Cu, Zn, Pb and Ca) in the top cm of 10 mineral soils in each compartment. Results showed that the lowest forest stand age and the forest structure created by management presented lower values of organic matter, soil moisture, water holding capacity and litterfall and higher values of C/N ratio in comparison with the highest forest stand age and the related forest structure, which generated differences in soil respiration and soil enzyme activities. The forest structure created by no forest management (control plot) presented the highest enzymatic activities, soil respiration, NH4(+) and NO3(-). Results did not show a clear trend in nutrient content comparing all the experimental areas. Finally, the multivariate PCA analysis clearly clustered three differentiated groups: Control plot; from 100 to 40years old and from 39 to 1year old. Our results suggest that the control plot has better soil quality and that extreme forest stand ages (100-80 and 19-1years old) and the associated forest structure generates differences in soil parameters but not in soil nutrient content. PMID:27099995

  11. Survey of food consumption by infants in Aomori prefecture

    International Nuclear Information System (INIS)

    We are collecting sociological data in relation to the estimation of radiation dose by radionuclides released from the nuclear fuel cycle facilities in Rokkasho-mura, Aomori Prefecture. This survey on the daily food intake by infants in Aomori Prefecture over a two-year period (1995-1996) is a continuation of a previous survey on individuals (≥ 5 years old). We investigated 179 infants in the age group around 4 years old and 181 infants in the age group around 1 year old. They were living in families belonging to three different groups of primary occupations: fishery workers, farmers and other occupations. The average total daily food consumption of the age group around 4 years old was about 958 grams/day/person (g/d/p), which was weighted according to the number of families in each of the three types of occupations in Aomori Prefecture. There was no significant difference shown for occupation and area. The consumption rates of marine, agricultural and livestock products and other products were around 45, 388, 256 and 268 g/d/p, respectively. Families of fishery workers showed a higher consumption of marine products, and families of farmers showed a higher consumption of agricultural products. The average total daily food consumption of the age group around 1 year old was about 627 g/d/p. The consumption rates of marine, agricultural and livestock products and other products were around 26, 251, 201 and 150 g/d/p, respectively. Compared with individuals over 5 years old, food consumption of the age group around 4 years old was about one-half, and the age group around 1 year old was about one-third. Consumption rates of marine products and agricultural products were low, and livestock products and other products were high in infants. As the age group became lower, the ratio of the quantity of dairy products became higher. (author)

  12. Effect of the activity of the Brazilian polyherbal formulation: Eucalyptus globulus Labill, Peltodon radicans Pohl and Schinus terebinthifolius Radd in inflammatory models

    Directory of Open Access Journals (Sweden)

    Karina C.P. Medeiros

    2007-03-01

    Full Text Available The Brazilian polyherbal formulation (BPF is composed by dyes of Eucalyptus globulus Labill, Peltodon radicans Pohl and Schinus terebinthifolius Raddi in alcohol at 13.3° GL. The formulation is popularly used in Paraíba state, Brazil since 1889 and it is used as an antiseptic and anti-inflammatory medicine. The aim of this study was to evaluate the anti-inflammatory property of the polyherbal formulation. For this purpose it was used the12-O-tetradecanoylphorbol 13-acetate (TPA and capsaicin-induced mouse ear edema and the carrageenan-induced rat paw edema. The BPF at dose of 26 mL/Kg inhibited both 12-O-tetradecanoylphorbol 13-acetate (TPA and capsaicin-induced ear edema by 49% (p O medicamento fitoterápico brasileiro - BPF é composto de corantes das plantas Eucalyptus globulus Labill, Peltodon radicans Pohl e Schinus terebinthifolius Raddi em alcool a 13,3° GL. Este medicamento é popularmente usado no estado da Paraíba, Brasil desde 1889 como anti-séptico e antiinflamatório. O objetivo deste estudo foi avaliar a propriedade antiinflamatória deste medicamento fitoterápico. Para tal, foram utilizadas as técnicas de edema de orelha em camundongos induzido por 12-O-tetradecanoilforbol 13-acetato (TPA ou capsaicina e o edema de pata de rato induzido por carragenina. O BPF na dose de 26 mL/kg inibiu tanto edema de orelha induzido por TPA como por capsaicina a 49% (p < 0.05 e 24% (p < 0.01 respectivamente. Estudos preliminares utilizando a técnica de edema de pata induzido por carragenina demonstraram que a administração oral também inibiu o edema de pata em aproximadamente 29%. Os resultados demonstraram que o medicamento fitoterápico brasileiro (BPF apresentou propriedades antiinflamatórias e a melhor dose foi aquela que é usada pela população.

  13. A case of congenital hypothyroidism presented with dysmyelinization findings

    Institute of Scientific and Technical Information of China (English)

    Sevil Ar Yuca; Cahide Ylmaz; Avni Kaya; Lokmanstyol; Ertan Sal; Yasar Cesur; Hseyin Caksen

    2014-01-01

    The central nervous system is one of the most crucial targeted systems of hyphotiroidism where tissues undergo various broad developmental processes such as neuronal and glial cellular differentiation, migration and myelinization.However brain images are mainly normal.In this article we present findings related to a1-year-old girl who has been referred to our outpatient clinic with complaints of slowing of movement and lack of interest.She was diagnosed with hypothyroidism.Her brain magnetic resonance image obtained during diagnosis displayed dysmyelinization.It showed improvement afterNa-L thyroxin therapy during follow up.

  14. Seasonal changes in the amount of carbohydrates and photosynthetic activity of Pinus pumila Regal on alpine in central Japan

    OpenAIRE

    Kibe,Takeshi; Masuzawa, Takehiro

    1992-01-01

    Branches and needles of Pmus pumila REGEL were collected from a site in the Yatsugatake mountain range in central Japan They were divided into current, 1-year-old, 2-year-old and 3-year-old parts Then, soluble carbohydrate (total sugars and starch) included in each of them was analyzed by SOMOGYI-NELSON method Photosynthetic rate of needles was measured by an infrared CO_2 gas analyzer Total sugar contents of branches and needles showed high levels in the winter season, but starch content lev...

  15. Impact of Gender in Renal Cell Carcinoma: The Relationship of FABP7 and BRN2 Expression with Overall Survival

    OpenAIRE

    Cheng Tan; Tatsuya Takayama; Naohisa Takaoka; Hiromi Fujita; Miki Miyazaki; Takayuki Sugiyama; Seiichiro Ozono

    2014-01-01

    OBJECTIVE To investigate the relationship between gender differences in fatty acid-binding protein7 (FABP7) and BRN2 (POU class 3 homeobox 2) expression in renal cell carcinoma (RCC) and the prognosis of patients with RCC. MATERIALS AND METHODS immunohistochemical (IHC) staining as well as reverse transcription-polymerase chain reaction (RT-PCR) was performed in renal tissues from 103 patients (83 men, mean age = 63.6 years old; 20 women, mean age = 63.1 years old) underwent radical nephrecto...

  16. Composition and stability of coyote families and territories in North Dakota

    Science.gov (United States)

    Allen, S.H.; Hastings, J.O.; Kohn, S.C.

    1987-01-01

    Coyote (Canis latrans) families studied in North Dakota during 1976 to 1978 contained three or more adults during the spring-summer season, and they occupied large contiguous, non-overlapping territories. Coyote territories averaged 61 km2 during the spring-summer season and 30 km2 during fall-winter season. Three of four families occupied territories that were similar in size for two consecutive years; however, boundaries changed within individual families when one or both alpha adults were killed. All coyotes replacing dead alpha adults were 1 year old.

  17. First Case Report of Canthariasis in an Infant Caused by the Larvae of Lasioderma serricorne (Coleoptera: Anobiidae)

    Science.gov (United States)

    Mokhtar, Aida Syafinaz; Sridhar, Ganiga Srinivasaiah; Mahmud, Rohela; Jeffery, John; Lau, Yee Ling; Wilson, John-James; Abdul-Aziz, Noraishah Mydin

    2016-01-01

    We report an unusual cause of gastrointestinal infection occurring in a 1-year-old infant patient who was brought to a public hospital in Kuala Lumpur, Malaysia. Larvae passed out in the patient’s feces were confirmed by DNA barcoding as belonging to the species, Lasioderma serricorne (F.), known as the cigarette beetle. We postulate that the larvae were acquired from contaminated food and were responsible for gastrointestinal symptoms in the patient. To our knowledge, this the first report of human canthariasis caused by larvae of L. serricorne. PMID:27208008

  18. Two renal tumors in cottontail rabbits (Sylvilagus floridanus).

    Science.gov (United States)

    Carlton, W W; Dietz, J M

    1977-01-01

    Renal tumors were found in two cottontail rabbits (Sylvilagus floridanus) about 1 year old. One tumor was intimately associated with the kidney and consisted of isolated ductular and tubular structures within an abundant connective tissue stroma and was diagnosed as a hamartoma of urogenital origin. The second was composed of epithelial cells arrange as alveolar structures with papillary projections, epithelium that was less differentiated into tubules and ducts, and neoplastic epithelial cells in solid sheets. The diagnosis of renal adenocarcinoma was based on the histologic features as metastasis had not occurred. PMID:850992

  19. Aneurysm of the superficial femoral artery in an infant

    International Nuclear Information System (INIS)

    An isolated arterial aneurysm in childhood is extremely rare. We report a 1-year-old girl with an aneurysm of the right superficial femoral artery, presenting as an asymptomatic mass of the thigh. The aneurysm involved the whole superficial femoral artery (9 cm in length), and surgical treatment would have required replacement of the affected artery. Conservative treatment was chosen, influenced by the patient's rapid growth at that time. Non-invasive, 3-D contrast-enhanced magnetic resonance angiography (MRA) was useful as an alternative to conventional angiography for detailed evaluation of the femoral arteries, including the aneurysm. (orig.)

  20. Imaging diagnosis: fibrodysplasia ossificans progressiva in a cat.

    Science.gov (United States)

    Klang, Andrea; Kneissl, Sibylle; Glänzel, Romana; Fuchs-Baumgartinger, Andrea

    2013-01-01

    A 1-year-old female cat was presented for progressive alopecia, gait abnormalities, and stiffness. Radiography demonstrated multiple calcified lesions within the soft tissues of the cervical and thoracic spine, shoulder, and limbs. Postmortem computed tomography provided more detailed information on the distribution, pattern, and extension of lesions. In addition, computed tomography helped guide sample selection for histopathology. The final diagnosis was fibrodysplasia ossificans progressiva. This is a rare disorder of unknown etiology, characterized by fibrosis and heterotopic bone formation in connective tissues. To the authors' knowledge, this is the first report describing this disease in a European cat.

  1. Mycorrhizae of Japanese black pine (Pinus thunbergii): Protection of seedlings from acid mist and effect of acid mist on mycorrhiza formation

    Energy Technology Data Exchange (ETDEWEB)

    Maehara, Noritoshi; Kikuchi, Junichi; Futai, Kazuyoshi

    1993-01-01

    To determine the effects of acid precipitation on Japanese black pine (Pinus thunbergii Parl.) with and without mycorrhizae (Pisolithus tinctorius (Pers.) Coker et Couch), 1-year-old seedlings were exposed to simulated acid rain mist, pH 3.0, for 10 min per day twice a week for 3 or 4 months. Simulated acid mist adversely affected the transpiration rate and lowered the extractable phosphorus content on seedlings, but seedlings with mycorrhizae were less affected by acid mist than were nonmycorrhizal seedlings. Simulated acid mist also retarded mycorrhiza formation. 41 refs., 7 figs.

  2. Changing the treatment of permanent neonatal diabetes mellitus from insulin to glibenclamide in a 4-month-old infant with kcnj11 activating mutation

    Directory of Open Access Journals (Sweden)

    Homa Ilkhanipoor

    2013-01-01

    Full Text Available Permanent neonatal diabetes mellitus (PNDM is a rare type of diabetes and KCNJ11 gene activating mutation is one of its prevalent causes. We introduced a 4-month-old male infant with poor feeding, restlessness, tachypnea, hyperglycemia, metabolic acidosis, and ketonemia. He was discharged with insulin and after 2 months, KCNJ11 gene mutation was found and treatment was switched from subcutaneous insulin to oral glibenclamide. Now, he is 1 year old with desirable glycemic control; therefore, genetic study is recommended for KCNJ11 gene mutation in such patients because if the mutation is found, treatment can be switched from insulin to sulfonylurea.

  3. The arbuscular mycorrhizal status of poplar clones selected for phytoremediation of soils contaminated with heavy metals

    Energy Technology Data Exchange (ETDEWEB)

    Takacs, T.; Radimszky, L.; Nemeth, T. [Research Inst. for Soil Science and Agricultural Chemistry of the Hungarian Academy of Sciences, Budapest (Hungary)

    2005-04-01

    The aim of this work was to study the colonization of indigenous arbuscular mycorrhizal fungi (AMF) species in fine-roots of poplar clones. Roots of 7 poplar clones were sampled from a 1-year-old trial established at an industrial site strongly polluted with heavy metals at Balatonfuezfoe, Hungary. The poplar clones have shown variable degrees of colonization by AMF, suggesting differential host susceptibility or mycorrhizal dependency. After outplanting the percentage of poplar survival was strongly correlated with the frequency of AMF infection. Two clones that survived at the lowest ratio after outplanting had not been colonized by AMF in contrast to those which survived to a much higher extent. (orig.)

  4. Some features of one-year-old tart Cherry shoots of cv. Sehattenmorelle

    OpenAIRE

    Dariusz Świetlik; Kazimierz Słowik; Sebastian Rejman

    2013-01-01

    The purpose of this study was to obtain data on the relationship between the length of 1-year-old shoots and their fruiting, and both their terminal and lateral growtn produced in the current year. The measurements were taken in 1977 and 1979 from the tart cherry trees of cv. Schattenmorelle grafted of Prunus mahaleb L. or Prunus avium L. grown in loose sandy soil. In 1977 there were more shoots of over 30 cm than in 1979. The longer the shoots, the more lateral shoots were there. Only the sh...

  5. Some features of one-year-old tart Cherry shoots of cv. Sehattenmorelle

    Directory of Open Access Journals (Sweden)

    Dariusz Świetlik

    2013-12-01

    Full Text Available The purpose of this study was to obtain data on the relationship between the length of 1-year-old shoots and their fruiting, and both their terminal and lateral growtn produced in the current year. The measurements were taken in 1977 and 1979 from the tart cherry trees of cv. Schattenmorelle grafted of Prunus mahaleb L. or Prunus avium L. grown in loose sandy soil. In 1977 there were more shoots of over 30 cm than in 1979. The longer the shoots, the more lateral shoots were there. Only the shortest shoots (1-10 cm bore more fruit per unit length as compared to the longer shoots.

  6. Perineal Accessory Scrotum with Congenital Lipoma: A Rare Case Report

    Directory of Open Access Journals (Sweden)

    Souvik Chatterjee

    2012-01-01

    Full Text Available A case of accessory scrotum in a 1-year-old boy is reported because of its rarity. A boy presented with a tumor mass attached with scrotum-like skin on its tip in the right side of perineum between the scrotum and anus. Both testes had descended into the scrotum. There was no other urological anomaly. Histological findings of the tumor indicated perineal lipoma, and the scrotum-like portion accessory scrotum. An overview of sequences during the normal development of male external genitalia has been provided and the deranged mechanism resulting in this anomaly has been reviewed with hypothesis regarding etiology of accessory scrotum.

  7. Brain CT scanning of children with purulent meningitis

    Energy Technology Data Exchange (ETDEWEB)

    Mishima, M.; Suzuki, M.; Nagata, M.; Kawamura, G.

    1986-12-01

    Nine of 21 children with purulent meningitis showed abnormal findings in brain CT when admitted. All of the abnormal group were less than 12 months of age, but 75 % of the normal group were more than 1 year old. The period of positive CRP was longer and the level of sugar in CSF was lower in abnormal group when compared with normal group. Because convulsion and EEG abnormalities were observed similarly in both groups, it may be difficult to determine the organic changes of the brain clinically. Brain CT scanning is recommended as soon as possible after the onset of purulent meningitis.

  8. Ecological aspects of cattle tick control in central Zambia.

    Science.gov (United States)

    Pegram, R G; Lemche, J; Chizyuka, H G; Sutherst, R W; Floyd, R B; Kerr, J D; McCosker, P J

    1989-07-01

    In ecological studies in central Zambia, both climate and ecotype affected population dynamics of tick species. Below average rainfall for several years caused a suppression in numbers of Rhipicephalus appendiculatus Neumann adults. Reduction in rainfall leading to changes in grazing patterns is thought to have been responsible for an increase in numbers of Amblyomma variegatum Fabricius adults in a grassland habitat. There were reasonable correlations between numbers of each tick species on individual hosts over 1 year old. However, there were no relationships between numbers of ticks and bovine lymphocyte antigens (BoLA). PMID:2519677

  9. Evaluation of Mird and Marinelli formalisms in the radiation dosimetry for thyroid of adults and children using {sup 131I} (radioiodine); Evaluacion de las dosimetrias Mird y de Marinelli en el estimado de dosis de radiacion para tiroides de adultos y ninos cuando se usa {sup 131}I (yoduro)

    Energy Technology Data Exchange (ETDEWEB)

    Vasquez, A.M.; Rocha, J.J.; Castillo, D.C.; Gomez, M.A.; Mendoza, A.A.; Rabanal, M.J.; Cruz, S.J. [Universidad Nacional de Trujillo (UNT-UCV), Trujillo (Peru). Grupo de Fisica Medica

    2013-11-01

    Using MIRD formalism and Cristy-Eckerman representation for the thyroid adults, children of 15, 10, 5, 1 year old and newborn it is shown that the total dose absorbed by the gland due to {sup 131}I(iodine) is its self-dose. Their results are not significantly different from those reported by the formalism MARINELLI (self-dose), which uses a sphere as glandular representation. Consequently, the kinetic model to the gland is a single compartment and the thyroid can be represented as a sphere.

  10. Comparative studies on the growth of pinus brutia in pure and mixed plantations

    Energy Technology Data Exchange (ETDEWEB)

    Hasan, S.M.; Al-Saraf, M.J.; Khalil, M.T.

    1980-01-01

    In trials in a semi-arid poor soil in Hammam Al-Alil, Mosul, Iraq, 2-year-old P. brutia transplants were planted in two blocks at 1x1 spacing. One block was interplanted with 1-year-old Acacia farnesiana. There was n.s.d. in growth of P. brutia between the 2 blocks at the end of the first or second year, but height growth in the mixed stand was significantly greater than in the pure stand after 3 growing seasons. (Refs. 10).

  11. Plant species richness and floristic composition change along a rice-pasture sequence in subsistence farms of Brazilian Amazon, influence on the fallows biodiversity (Benfica, State of Para)

    OpenAIRE

    Mitja, Danielle; Miranda, L. D. S.; Velasquez, Elena; Lavelle, Patrick

    2008-01-01

    Along the Amazonian pioneer front in the Brazilian state of Pari, smallholder farmers manually clear primary rain forest every year to grow rice prior to sowing pastures that they will use for 5-20 years. Species richness and floristic composition of the weedy species were studied in 20 plots along a farming succession, from rice fields, to 1-year-old, 4-8-year-old and over 10-year-old pastures planted to Brachiaria brizantha. In the early phases of the farming cycle reduction in the average ...

  12. Familial dysautonomy (Riley-Day syndrome

    Directory of Open Access Journals (Sweden)

    Edward R. Tonholo Silva

    1994-03-01

    Full Text Available Familial dysautonomia, also known as Riley-Day syndrome, is a disorder of autonomic nervous system with an autosomal recessive mode of inheritance. Reduction and/or loss of unmyelinated and small myelinated fibers is found, as reduction of dopamine beta-hydroxylase in blood. The diagnosis is based on clinical features: diminished lacrimation, insensitivity to pain, poor temperature control, abolished deep tendon reflexes, postural hypotension, vomiting attacks, poor motor coordenation, and mental retardation. The treatment is symptomatic and many children die during the first years of life, usually as a result of repeated aspiration pneumonia. We report the case of a 1 year-old child with familial dysautonomia.

  13. Vitamin D Status: A Different Story in the Very Young versus the Very Old Romanian Patients

    OpenAIRE

    Chirita-Emandi, Adela; Socolov, Demetra; Haivas, Carmen; Calapiș, Anca; Gheorghiu, Cristina; PUIU, Maria

    2015-01-01

    Background In Romania (latitude 48°15’N to 43°40’N), vitamin D supplementation is common practice mostly in infants 0-1 year old. No published information is available regarding epidemiological data on vitamin D status in the Romanian population for a wide age range and geographical territory. In this context, we aimed to evaluate the seasonal and age variation of vitamin D status in a large Romanian population. Methods 6631 individuals from across Romania had performed 7544 vitamin D assessm...

  14. Cardiopatías y embarazo

    Directory of Open Access Journals (Sweden)

    Francisco de Jesús Valladares Carvajal

    2011-01-01

    Full Text Available La cardiopatía es la causa más frecuente de muerte materna indirecta en el mundo. Es decir, la presencia de enfermedad cardíaca no excluye el embarazo, pero aumenta el riesgo para la madre y para el feto y requiere de un tratamiento especial. Los cambios hemodinámicos propios del embarazo pueden hacer sospechar la presencia de enfermedad cardíaca, por lo que es importante conocer los síntomas y signos indicadores de cardiopatía estructural en la mujer embarazada. La morbimortalidad materna dependerá del tipo de cardiopatía y de la capacidad funcional en el momento de la concepción. De otro lado las gestaciones en madres cardiópatas se han asociado también a mayor incidencia de problemas para el feto, y por tanto, de un aumento de la mortalidad perinatal.

  15. Baja Andesia: sed y poéticas tramontinas. Un desvío etnográfico a mano alzada

    Directory of Open Access Journals (Sweden)

    Pedro Araya

    2007-07-01

    Full Text Available Si yo fuese dromedario no tendría sed. ¿Qué hora es ?Vicente Huidobro1.El antropólogo-poeta-ponencista despierta luego de un sueño intranquilo. Tiene sed. Algo recuerda. Un escozor, dice, un poco antes, en la misma, como de ron, como de vino y el fumadero de las caras ; como si, apenas, algo de lo exagerado de una opinión, entre una cosa y la otra, hubiera olvidado. Sabe que debe hablar aquella misma mañana. Sabe. La pata de los caballos, piensa. La tribu estará reunida. No la suya. No se sus...

  16. Luces y sombras en la historia de los grupos indígenas en Sonora, siglos XIX-XXI. Panorama historiográfico

    Directory of Open Access Journals (Sweden)

    Zulema Trejo Contreras

    2015-01-01

    Full Text Available en este artículo se presenta un análisis panorámico respecto a la historiografía de los grupos indígenas mayo, yaqui y ópata; el objetivo es conocer cómo ha evolucionado la forma en que se les ha estudiado. Se destaca la concepción dualista de los autores respecto a las etnias, la inserción de los textos revisados en el contexto historiográfico nacional y la manera como han ido cambiando los temas de estudio en relación con la historia de los grupos indígenas de Sonora.

  17. : ESSAI D'INTERPRETATION

    OpenAIRE

    Chamoux, Marie Noëlle

    2006-01-01

    Este capítulo presenta, a partir del léxico y de textos en náhuatl del siglo XVI, las formas que usaban los aztecas pata expresar los conocimientos técnicos, la pericia, la enseñanza y el aprendizaje. Subrayaban la habilidad para planificar y anticipar la acción técnica. Daban criterios de lo "bello" y de lo "bien hecho". En sus discursos, daban relieve a los aspectos cognitivos y psicológicos, más que a lo manual, y insistían en las cualidades éticas. Ce chapitre présente, à partir du lex...

  18. Efeito analgésico de longa duração da dipirona sobre a hiperalgesia persistente induzida pela constrição do nervo ciático em ratos: participação do óxido nítrico Long term analgesic effect of dipyrone on the persistent hyperalgesia induced by chronic constriction injury of sciatic nerve in rats: involviment of nitric oxide

    OpenAIRE

    Fábio José Reis; Noeli Pereira Rocha

    2006-01-01

    O efeito analgésico de longa duração da dipirona foi avaliado em um modelo de dor neuropática assim como a participação da via óxido nítrico-GMPc neste mecanismo analgésico. Uma única administração intraplantar de dipirona (80 µg), no 14º dia após a instalação da hiperalgesia neuropática induzida pela constrição do nervo ciático exerceu um efeito analgésico, significativo e de longa duração. A inibição da óxido nítrico sintetase com L-NAME (50 ou 100 µg/pata), ou do óxido nítrico (NO) endógen...

  19. SBLECCI0N DE LOS BISCHE SOS DEL PRESIDENTE ABDEL NASER

    Directory of Open Access Journals (Sweden)

    Team of authors

    2014-11-01

    Full Text Available Pref acio : E;1xtractamos se~ guidamente algunas de ]a pata-bras del Presidente Abdel Na-ser, pronun-ciadag en difereiltes oeasioncs, y las traducimos a las divers as lenguas quß se hablan en esta escuela, Inten-tam.es con elio ofrecer ai mundo oriental y occi dental ima foto viva de la lucha. del pueblo araba por la causa de la libertad y la construcción de una soctedad democràtica, socialista, cooperativa y sana. Para que ccnozea el mundo la reali-dad del nacionalismo àrabe y aprenda sus objetivos de na-cionalismo y paK. Sera cl mensa je de nuestra escuela a ia Patria.

  20. Contribuição ao conhecimento da morfologia de Oxyagrion Terminale Selys, 1876 com um estudo sobre a genitália externa (Odonata, Zygoptera, Coenagrionidae

    Directory of Open Access Journals (Sweden)

    Jane Margaret Costa

    1984-09-01

    Full Text Available Foi feita uma análise minuciosa da morfologia externa de Oxyagrion terminale Selys, 1876, onde foram interpretadas as principais estruturas da cabeça, tórax, patas, asas e abdômen vistos de vários ângulos, dando especial atenção ao estudo da genitália de ambos os sexos, em microscopia ótica e eletrônica de varredura.A full description of the external morphology of Oxyagrion terminale Selys, 1876, was made through optical microscopy and scanning electron microscopy. The main structures of the head, torax, legs, wings and abdomen, were studied with specieal attention to the genital structures of both sexes.

  1. Órdenes de no reanimar y cuidados paliativos en pacientes fallecidos en un servicio de cardiología : ¿Qué podemos mejorar?

    OpenAIRE

    Martínez Sellés Oliveria Soares, Manuel

    2010-01-01

    Con el objetivo de evaluar el uso de órdenes de no reanimar y de cuidados paliativos en cardiópatas, registramos 198 muertes consecutivas en nuestro servicio. En 113 (57%) se decidió no reanimar, se reflejó en la historia clínica en 102 (90,3%) y en 74 (65,5%) en las hojas de enfermería. Se informó a 5 pacientes (4,4%) y a 95 familias (84,1%). El uso de medidas paliativas fue escaso en pacientes no reanimables, 56 (49,6%) recibieron cloruro mórfico y 5 (4,4%), asistencia espiritual. Sin embar...

  2. Beklemishevia hispaniola n. sp., nuevo representante de la Cohorte Palaeosomata (Acari, Oribatei en España

    Directory of Open Access Journals (Sweden)

    Pérez-Iñigo, C.

    1996-12-01

    Full Text Available A new species of oribatid mite (Acari, Oribatei belonging to the family Ctenacaridae (Cohors Palaeosomata is described; this species was recorded several times in Spain as Beklemishevia galeodula Zachvatkin, 1945. The new species is easily distinguishable from the mentioned one because of the presence of three claws in every leg, a noticeable pigidial neotrichy and the absence of short, almost spiniform, setae on the pygidium.Se describe una nueva especie de oribátido (Acari, Oribatei perteneciente a la familia Ctenacaridae (Cohorte Palaeosomata que habia sido citada varias veces en España como Beklemishevia galeodula Zachvatkin, 1945, y de la que se diferencia por presentar tres uñas en todas las patas, una acentuada neotriquia pigidial y carecer de setas cortas espiniformes en el pigidio.

  3. La radio en la difusión universitaria. A la búsqueda de sentido

    Directory of Open Access Journals (Sweden)

    Lourdes de Quevedo Orozco

    2004-01-01

    Full Text Available Un panorama ideal de la radio universitaria en México sería contar con un amplio número de emisoras en el cuadrante, semejante al conjunto de los centros educativos profesionales del país. Ésta es la imagen del mundo al revés, como bien dice el escritor Eduardo Galeano en Patas arriba. Un mundo que nos enseña a padecer la realidad en lugar de cambiarla, a olvidar el pasado en lugar de escucharlo y a aceptar el futuro en lugar de imaginarlo. Este artículo presta oídos a algunas voces del pasado, con el fin de encontrar sentido a la situación presente de la radiodifusión universitaria. Lanza al aire algunas ideas para participar en la creación de un posible futuro hertziano.

  4. Productividad secundaria en los esteros de la barra de arena El Mogote en la Ensenada de La Paz, Baja California Sur, México Secondary productivity in the estuaries of El Mogote sand bar in Ensenada de La Paz, Baja California Sur, Mexico

    Directory of Open Access Journals (Sweden)

    Jorge A. López-Rocha

    2012-04-01

    Full Text Available Los ecosistemas de manglar son un hábitat crítico para numerosas especies y su productividad es importante por su contribución de detritos orgánicos y su producción secundaria. El objetivo del trabajo fue definir indicadores de productividad secundaria para establecer una línea base que permita medir alteraciones en el sistema de manglar por posibles perturbaciones naturales o antropogénicas. Como indicadores se escogieron los moluscos bivalvos pata de mula, Anadara tuberculosa y el ostión de mangle, Crassostrea palmula. Se realizaron muestreos en tres esteros de agosto de 2007 a julio de 2009. Se estimó la abundancia y la producción secundaria con base en el incremento de biomasa. Para la estimación del incremento en peso se usaron las tasas de crecimiento individual obtenidas mediante un análisis de distribuciones de frecuencia de tallas. La abundancia promedio fue de 1.27 y 510 ind · m-2 de la pata de mula y ostión de mangle respectivamente. Se estimó una tasa de crecimiento de 4.91 mm · mes-1 (3.67 g · mes-1 para la pata de mula y de 3.80 mm · mes-1 (0.18 g · mes-1 para el ostión de mangle. La producción secundaria promedio de pata de mula fue de 4.51 g · m-2 · mes-1 y fue mayor durante la primavera, mientras que para el ostión de mangle fue de 97.9 g · m-2 · mes-1, registrándose la máxima producción durante el verano. Los resultados obtenidos demuestran que estos indicadores de calidad del bentos son adecuados para medir alteraciones al sistema de manglar de la Ensenada de La Paz, B. C. S., México.Mangrove ecosystems are critical habitats for many species, and their productivity is important because of their contribution of organic detritus and secondary production. The objective of this study was to identify suitable indicators of secondary productivity of mangrove systems, in order to establish a baseline for measuring changes in the mangrove system due to natural or anthropogenic potential disturbances. The

  5. A connection between free and classical infinite divisibility

    DEFF Research Database (Denmark)

    Barndorff-Nielsen, Ole Eiler; Thorbjørnsen, Steen

    2004-01-01

    In this paper we continue our studies, initiated in Refs. 2–4, of the connections between the classes of infinitely divisible probability measures in classical and in free probability. We show that the free cumulant transform of any freely infinitely divisible probability measure equals the class......In this paper we continue our studies, initiated in Refs. 2–4, of the connections between the classes of infinitely divisible probability measures in classical and in free probability. We show that the free cumulant transform of any freely infinitely divisible probability measure equals...... the classical cumulant transform of a certain classically infinitely divisible probability measure, and we give several characterizations of the latter measure, including an interpretation in terms of stochastic integration. We find, furthermore, an alternative definition of the Bercovici–Pata bijection, which...

  6. Propriedades farmacológicas do extrato etanólico de Eremanthus erythropappus (DC. McLeisch (Asteraceae Pharmacological properties of the ethanol extract from Eremanthus erythropappus (DC. McLeisch (Asteraceae

    Directory of Open Access Journals (Sweden)

    Marcelo S. Silvério

    2008-09-01

    Full Text Available O presente trabalho investigou as propriedades antinociceptiva, antiinflamatória e antiulcerogênica do extrato etanólico dos galhos de E. erythropappus. Foram realizados os testes de contorções abdominais induzidas por ácido acético; tempo da lambida da pata induzida por formalina; placa quente; edema de pata induzido por carragenina; lesões ulcerativas induzidas por indometacina e etanol. As doses de 50, 100 e 200 mg/kg inibiram as contorções em 43,07%, 69,34% e 70,07%, respectivamente. O tempo da lambida da pata foi reduzido em ambas as fases nas doses testadas, enquanto o tempo de latência da placa quente teve efeito significativo na dose de 200 mg/kg. O edema de pata foi reduzido em 23,81% (100 mg/kg e 47,62% (200 mg/kg. O índice ulcerativo das lesões induzidas por indometacina foi reduzido na dose de 100 mg/kg e 200 mg/kg, enquanto a dose de 200 mg/kg teve efeito significativo sobre o volume e o pH do suco gástrico. O índice ulcerativo e o volume do suco gástrico, induzidos por etanol, foram reduzidos na dose de 200 mg/kg, enquanto o pH do suco gástrico aumentou nas doses de 100 e 200 mg/kg. Os resultados indicam que o extrato etanólico de E. erythropappus avaliado pode constituir alvo potencial para uso em terapias da dor, da inflamação e de úlcera.The present work investigated the antinociceptive, anti-inflammatory and antiulcerogenic activities of Eremanthus erythropappus ethanol extract. The tests were carried out by acetic acid writhing, paw licking induced by formalin, hot plate, indomethacin- and ethanol-induced ulcer. The doses of 50, 100 and 200 mg/kg inhibited the contortions in 43.07, 69.34 and 70.07%, respectively. Both phases of paw lick were reduced at the tested doses, while reaction time at hot plate had significant effect at 200 mg/kg. The paw edema was decreased in 23.81% (100 mg/kg and 47.62% (200 mg/kg. The index of ulceration induced by indomethacin was reduced at the doses of 100 and 200 mg

  7. El Sulfato de Magnesio prepinzamiento aórtico como preservador energético en cirugía cardíaca

    OpenAIRE

    Santos Gracia, José Juan

    2003-01-01

    Hay evidencia de un déficit crónico de magnesio en la población mundial atribuido a ingestión deficitaria. En los cardiópatas, la utilización de drogas depletoras agrava este déficit y contribuye a la aparición de arritmias malignas. El magnesio ha sido recomendado en el tratamiento del Infarto Agudo del Miocardio por preservar la energía de la célula cardíaca isquémica o reperfundida desde la era “pretrombolítica” y en todas las variantes de arritmias. Sin embargo, su utilización en cardioci...

  8. Estudo histológico e histoquímico da pele de jurará Kinosternon scorpioides scorpioides (Testudines: Kinosternidae)

    OpenAIRE

    Ana L Abreu-Silva; José A. Silva; Katiene R.S. Souza; Débora M.S. Santos; José G. Pereira; Rafael C. Carvalho; Ambrosio, Carlos E; Miglino, Maria A

    2014-01-01

    O objetivo do presente trabalho foi analisar histológica e histo- químicamente a pele do jurará (Kinosternon scorpioides scorpioides). Foram utilizados seis animais (três machos e três fêmeas). Os animais foram eutanasiados com dose letal de tiopental sódico a 2,5%, para colheita de fragmentos de pele mole das patas e pescoço do animal, que após a fixação em líquido de Bouin, foram incluídos em parafina e corados pelas técnicas de hematoxilina-eosina, Giemsa, Sirius red, Reticulina de Gomori ...

  9. La globalización y su impacto en la economía de la educación en el sistema educativo público de Puerto Rico

    Directory of Open Access Journals (Sweden)

    Pizarro Figueroa, J.

    2010-01-01

    Full Text Available En este mundo globalizado la educación se constituye en un factor indispensable pata el crecimiento del ser humano y su sociedad. La educación es determinante para el crecimiento económico, social y ecológico de un país. En este ensayo presentamos un análisis sobre la economía de la educación. A tales fines, comenzaremos discutiendo el concepto de la globalización y sus características, tanto sus ventajas como desventajas. Posteriormente, analizaremos la economía de la educación en el Sistema Educativo Público del Estado Libre Asociado de Puerto Rico (territorio no incorporado de los Estados Unidos de América. Cómo la economía incide en la educación y viceversa. Finalmente, presentaremos las conclusiones producto de este ensayo.

  10. Crítica de Libros.

    Directory of Open Access Journals (Sweden)

    Fernando Colina Pérez

    1981-01-01

    Full Text Available

    PRESENTACION y ENSEÑANZAS DE SCHREBER, Daniel Paul Schreber -«Memorias de un Neurópata» -Ediciones Petrel. Buenos Aires -1978

    LA TEORIA COMO FICCION, Maud Mannoni -Editorial Crítica -1980

    MAS ALLA DE LA SOCIOLOGIA: EL GRUPO DE DISCUSION: TEORIA y CRITICA, Jesús Ibáñez -Ed. Siglo XXI -Madrid, 1979.

    LA SEXUALIDAD -Jean Laplanche

    EL ORDEN PSIQUIATRICO -Robert Castel -Ediciones La Piqueta. Madrid, 1980 -Colección «La Genealogía del Poder», dirigida por Julia Varela y Fernando Alvarez Uría

  11. A relevância dos conteúdos petcare para os utilizadores nas plataformas digitais

    OpenAIRE

    Carvalho, Marta Sofia Saldanha de

    2016-01-01

    A maioria dos lares portugueses já conta com a presença de animais de estimação, assistindo-se assim a uma maior consciencialização para cuidar e garantir qualidade de vida aos seus companheiros, na sua maioria de quatro patas. A consciencialização dos direitos dos animais, os novos hábitos e estilo de vida contribuíram para o aumento da adoção de animais domésticos, que hoje em dia já são considerados por muitos como membros da família. Esta dissertação de mestrado centra-se n...

  12. Avaliação do efeito antiparasitário do omeprazol na prevenção do desenvolvimento de lesões cutâneas em hamsters infectados por Leishmania brasiliensis Evaluation of omeprazole's antiparasitary effect preventing the development of cutaneous lesions due to Leishmania brasiliensis in hamsters

    Directory of Open Access Journals (Sweden)

    Hélio Amante Miot

    2005-12-01

    Full Text Available FUNDAMENTOS: A leishmaniose tegumentar americana permanece doença endêmica em diversas regiões brasileiras. A sobrevivência do parasita no interior dos macrófagos se deve, em parte, pela atividade de uma K+/H+-ATPase de membrana que pode ser inibida pelo omeprazol. OBJETIVOS: Avaliar a eficácia do omeprazol na prevenção do desenvolvimento de lesões de leishmaniose em hamsters. MÉTODOS: Empregaram-se 18 hamsters, divididos em três grupos: o grupo L recebeu apenas a inoculação de L. brasiliensis na pata anterior direita, o grupo O recebeu apenas doses diárias de 0,4mg de omeprazol subcutâneo, e o grupo L+O recebeu o inóculo de leishmanias e o tratamento com omeprazol desde o dia da inoculação. O estudo foi conduzido por 42 dias, realizaram-se medidas dos diâmetros das patas semanalmente, e, ao final do estudo, foram realizados esfregaços das lesões para verificação dos parasitas. RESULTADOS: Os hamsters dos grupos L e L+O desenvolveram lesões de leishmaniose tegumentar havendo ulceração em duas patas do grupo L e uma do grupo L+O. Ao final do estudo, a mobilidade e vitalidade no grupo L foram menores que em L+O, e estas menores que no grupo O. Os diâmetros das patas inoculadas nos grupos L e L+O foram significativamente maiores que no início do estudo (pBACKGROUND: Cutaneous leishmaniasis remains an endemic disease in several brazilian regions. The parasite’ survival in macrophages is due to a membrane K+/H+-ATPase that can be inhibited by omeprazole. OBJECTIVES: Evaluate omeprazole’s efficacy preventing the development of cutaneous leishmaniasis in hamsters. METHODS: Eighteen hamsters were divided in 3 groups: the L group received an inoculation of L. brasiliensis on right paw, the O group received daily 0,4mg omeprazole subcutaneously, and L+O group received both omeprazole and the inocule. The study was performed in 42 days, and the measurements of the diameter of paws were done weekly. At the end of the study

  13. ‘COROJO 2006’: NUEVA VARIEDAD CUBANA DE TABACO NEGRO (Nicotiana tabacum L.

    Directory of Open Access Journals (Sweden)

    Vivaldo García Morejón

    2013-01-01

    Full Text Available En la Estación Experimental del Tabaco, de San Juan y Martínez, Pinar del Río durante la campaña tabacalera 2001-2002, se realizó un cruzamiento sexual con el objetivo de obtener una variedad de tabaco negro con mayor rendimiento que la comercial ‘Criollo 98’, resistente al moho azul ( Peronospora hyocyami de Bary, a la pata prieta ( Phytophthora parasitica Dast. var . Nicotianae Breda de Haan, al virus del mosaico del tabaco (VMT y a la necrosis ambiental. Después de cinco generaciones de autofecundación y selección por el método genealógico se obtuvieron siete variedades resistentes. El cruce originó la nueva variedad `Corojo 2006 ́ que superó a la `Criollo 98 ́.

  14. Processing of Phonemic Consonant Length: Semantic and Fragment Priming Evidence from Bengali.

    Science.gov (United States)

    Kotzor, Sandra; Wetterlin, Allison; Roberts, Adam C; Lahiri, Aditi

    2016-03-01

    Six cross-modal lexical decision tasks with priming probed listeners' processing of the geminate-singleton contrast in Bengali, where duration alone leads to phonemic contrast ([pata] 'leaf' vs. [pat:a] 'whereabouts'), in order to investigate the phonological representation of consonantal duration in the lexicon. Four form-priming experiments (auditory fragment primes and visual targets) were designed to investigate listeners' sensitivity to segments of conflicting duration. Each prime derived from a real word ([k(h)[symbol: see text]m]/[g(h)en:]) was matched with a mispronunciation of the opposite duration (*[k(h)[symbol: see text]m:]/*[g(h)en]) and both were used to prime the full words [k(h)[symbol: see text]ma] ('forgiveness') and [g(h)en:a] ('disgust') respectively. Although all fragments led to priming, the results showed an asymmetric pattern. The fragments of words with singletons mispronounced as geminates led to equal priming, while those with geminates mispronounced as singletons showed a difference. The priming effect of the real-word geminate fragment was significantly greater than that of its corresponding nonword singleton fragment. In two subsequent semantic priming tasks with full-word primes a stronger asymmetry was found: nonword geminates (*[k(h)[symbol: see text]m:a]) primed semantically related words ([marjona] 'forgiveness') but singleton nonword primes (*[ghena]) did not show priming. This overall asymmetry in the tolerance of geminate nonwords in place of singleton words is attributed to a representational mismatch and points towards a moraic representation of duration. While geminates require a mora which cannot be derived from singleton input, the additional information in geminate nonwords does not create a similar mismatch. PMID:27089807

  15. Differences in MRI findings between subgroups of recent-onset childhood arthritis

    Energy Technology Data Exchange (ETDEWEB)

    Kirkhus, Eva [Oslo University Hospital, Rikshospitalet, Department of Radiology, Oslo (Norway); Flatoe, Berit; Smith, Hans-Joergen [Oslo University Hospital, Rikshospitalet and University of Oslo, Faculty of Medicine, Department of Radiology, Oslo (Norway); Riise, Oeystein [Oslo University Hospital, Rikshospitalet, Department of Pediatrics, Oslo (Norway); Reiseter, Tor [Oslo University Hospital, Ullevaal, Department of Radiology, Oslo (Norway)

    2011-04-15

    MRI is sensitive for joint inflammation, but its ability to separate subgroups of arthritis in children has been questioned. Infectious arthritis (IA), postinfectious arthritis (PA), transient arthritis (TA) and juvenile idiopathic arthritis (JIA) are subgroups that may need early, different treatment. To determine whether MRI findings differ in IA, PA/TA and JIA in recent-onset childhood arthritis. Fifty-nine children from a prospective study of incidence of arthritis (n = 216) were, based on clinical and biochemical criteria, examined by MRI. Joint fluid, synovium, bone marrow, soft tissue and cartilage were scored retrospectively and analysed by Pearson chi-square test and logistic regression analysis. Fifty-nine children had MRI of one station. IA was suggested by bone marrow oedema (OR 7.46, P = 0.011) and absence of T1-weighted and T2-weighted low signal intensity synovial tissue (OR 0.06, P = 0.015). Furthermore, soft-tissue oedema and reduced contrast enhancement in the epiphyses were more frequent in children with IA. JIA correlated positively with low signal intensity synovial tissue (OR 13.30, P < 0.001) and negatively with soft-tissue oedema (OR 0.20, P = 0.018). No significant positive determinants were found for PA/TA, but bone marrow oedema, soft-tissue oedema, irregular thickened synovium and low signal intensity synovial tissue was less frequent than in IA/JIA. In children with high clinical suspicion of recent onset arthritis, there was a significant difference in the distribution of specific MRI features among the diagnostic groups. (orig.)

  16. Differences in MRI findings between subgroups of recent-onset childhood arthritis

    International Nuclear Information System (INIS)

    MRI is sensitive for joint inflammation, but its ability to separate subgroups of arthritis in children has been questioned. Infectious arthritis (IA), postinfectious arthritis (PA), transient arthritis (TA) and juvenile idiopathic arthritis (JIA) are subgroups that may need early, different treatment. To determine whether MRI findings differ in IA, PA/TA and JIA in recent-onset childhood arthritis. Fifty-nine children from a prospective study of incidence of arthritis (n = 216) were, based on clinical and biochemical criteria, examined by MRI. Joint fluid, synovium, bone marrow, soft tissue and cartilage were scored retrospectively and analysed by Pearson chi-square test and logistic regression analysis. Fifty-nine children had MRI of one station. IA was suggested by bone marrow oedema (OR 7.46, P = 0.011) and absence of T1-weighted and T2-weighted low signal intensity synovial tissue (OR 0.06, P = 0.015). Furthermore, soft-tissue oedema and reduced contrast enhancement in the epiphyses were more frequent in children with IA. JIA correlated positively with low signal intensity synovial tissue (OR 13.30, P < 0.001) and negatively with soft-tissue oedema (OR 0.20, P = 0.018). No significant positive determinants were found for PA/TA, but bone marrow oedema, soft-tissue oedema, irregular thickened synovium and low signal intensity synovial tissue was less frequent than in IA/JIA. In children with high clinical suspicion of recent onset arthritis, there was a significant difference in the distribution of specific MRI features among the diagnostic groups. (orig.)

  17. Redescription of Pectiniunguis gaigei (Chamberlin, 1921 from Guyana, with new distributional data and complementary descriptive notes on similar neotropical species (Chilopoda: Geophilomorpha: Schendylidae

    Directory of Open Access Journals (Sweden)

    Luis Alberto Pereira

    2010-01-01

    Full Text Available Pectiniunguis gaigei (Chamberlin, 1921 from Guyana, (Chilopoda: Geophilomorpha: Schendylidae is here redescribed and illustrated on the basis of type material. The species is characterized by the absence of pore-field on the first sternum; presence of undivided ventral pore-fields in an uninterrupted series along the whole trunk length; parunguis of walking legs thin and pale; and last leg praetarsus as a small tubercle with numerous spines. All these combined traits are shared by three other Neotropical members of the genus (P. geayi (Brölemann & Ribaut, 1911 from Brazil; P. ducalis Pereira, Minelli & Barbieri, 1995 from Brazil; and P. roigi Pereira, Foddai & Minelli, 2001 from Ecuador, with which P. gaigei is here compared in detail. New distributional records for P. ducalis and P. geayi, together with complementary descriptive notes and new diagnoses for these species and P. roigi, are also given.Pectiniunguis gaigei (Chamberlin, 1921 de Guyana, (Chilopoda: Geophilomorpha: Schendylidae es aquí redescripta e ilustrada en base a material tipo. La especie se caracteriza por la ausencia de campo de poros en el primer esternito; presencia de campos de poros ventrales simples en una serie continua a lo largo de todo el tronco; parunguis de las patas ambulatorias finos y de coloración pálida; y pretarso del último par de patas en forma de un pequeño tubérculo provisto de numerosas espinas. Todos estos caracteres combinados son compartidos por otros tres miembros neotropicales del género (P. geayi (Brölemann & Ribaut, 1911 de Brasil; P. ducalis Pereira, Minelli & Barbieri, 1995 de Brasil; y P. roigi Pereira, Foddai & Minelli, 2001 de Ecuador, con los cuales P. gaigei es aquí comparada en detalle. Nuevos registros de distribución geográfica para P. ducalis y P. geayi, junto con notas descriptivas complementarias y nuevas diagnosis para estas especies y P. roigi, son también brindados.

  18. Caracterización de las gestantes con cardiopatías en el Hospital Docente Ginecobstétrico “Ramón González Coro”

    Directory of Open Access Journals (Sweden)

    Yanara Gutierrez Aliaga

    2011-11-01

    Full Text Available Introducción: el embarazo en las mujeres cardiópatas constituye hoy, la primera causa de morbi-mortalidad materna entre las patologías asociadas al embarazo. Objetivo: caracterizar a las gestantes con cardiopatía desde el punto de vista clínico y demográfico. Método: estudio observacional, descriptivo y retrospectivo con algunos elementos analíticos, realizado en el Servicio de Cardiopatía y Embarazo del Hospital Docente Ginecobstétrico “Ramón González Coro”, del 2000-2009. El universo estuvo constituido por las 472 gestantes cardiópatas atendidas durante ese periodo y a las que se le aplicó el protocolo diseñado desde el año 2000. Los datos: edad materna, clasificación funcional en primer y tercer trimestres, motivo de ingreso, medicamentos utilizados y complicaciones cardiovasculares, se obtuvieron a través de una encuesta y se procesaron mediante el sistema estadístico SPSS- 11,5, utilizando frecuencias absolutas y relativas. Resultados: las valvulopatías, (25,6 % fue el tipo de cardiopatía más frecuente, se encontraron modificaciones importantes en el grado funcional al terminar el embarazo, se presentaron complicaciones en 29,9 % de las pacientes, las más frecuentes fueron: edema agudo pulmonar (6,4 %, la insuficiencia cardiaca (4,3 % y las arritmias (3,5 %. El tromboembolismo pulmonar fue la causa de las dos muertes maternas que hubo. Conclusión: Las valvulopatías resultaron ser las cardiopatías más frecuentes en nuestras gestantes clasificándose la mayor parte de estas en grado funcionl I y constituyendo el embarazo una agravante potencial para ellas.

  19. Efeitos farmacológicos e toxicológicos do extrato de Posoqueria acutifolia Mart. (Rubiaceae em roedores

    Directory of Open Access Journals (Sweden)

    O. V. SOUSA

    2009-01-01

    Full Text Available

    O presente trabalho investigou os efeitos farmacológicos e toxicológicos do extrato metanólico dos galhos de Posoqueria acutifolia. Foram realizados os testes de contorções abdominais, formalina, placa quente, edema de pata e pleurisia, bem como para a toxicidade aguda. As doses de 100, 200 e 400 mg/kg inibiram as contorções abdominais. No teste da formalina, a dose de 400 mg/kg reduziu o tempo de lambida da primeira fase, enquanto este efeito foi observado nas doses de 200 e 400 mg/kg sobre a segunda fase. O tempo de permanência sobre a placa quente aumentou na dose de 400 mg/kg, embora a dose de 200 mg/kg também tenha tido efeito significativo após 90 minutos de tratamento. Houve uma redução do edema de pata, do volume do exsudato e da migração leucocitária nas doses testadas. O extrato testado não foi tóxico nas doses avaliadas. Portanto, o extrato metanólico de P. acutifolia exibe efeitos analgésico e antiinflamatório, o que poderia estar relacionado a seu uso na medicina popular. Palavras-chave: Posoqueria acutifolia; Rubiaceae; efeito analgésico; efeito antiinflamatório; toxicidade aguda.

  20. Interspecies scaling of the pharmacokinetics of N-nitrosodimethylamine.

    Science.gov (United States)

    Gombar, C T; Harrington, G W; Pylypiw, H M; Anderson, L M; Palmer, A E; Rice, J M; Magee, P N; Burak, E S

    1990-07-15

    The pharmacokinetics of N-nitrosodimethylamine was studied in patas monkeys following i.v. doses of 0.5, 1.0, and 5.0 mg/kg and a p.o. dose of 1.0 mg/kg, and in Swiss mice at i.v. doses of 1.0 and 2.0 mg/kg. In the patas monkey the pharmacokinetics was linear over the i.v. dose range studied. The mean clearance (Cl), steady-state volume of distribution (Vss), mean residence time, and elimination half-life (t 1/2) were 103.3 +/- 26.7 (SD) ml/min, 3061 +/- 821 ml, 30.8 +/- 10.8 min, and 21.1 +/- 8.5 min, respectively. Assuming that the pharmacokinetics was linear at the p.o. dose used, the p.o. bioavailability of N-nitrosodimethylamine in the monkey was 49%. The pharmacokinetics was also linear in mice, and the average Cl, Vss, mean residence time, and t 1/2 were 3.81 ml/min, 21.0 ml, 5.5 min, and 11.9 min, respectively. These data and data for rats, hamsters, rabbits, dogs, and pigs taken from the literature were used to scale Cl and Vss to body weight using the allometric equation. The resulting equation for Cl was Cl = 49.7B0.998 and the equation for Vss was Vss = 748B1.05 where B is body weight in kg. The fit of the data to the equation was excellent in both cases. Using these equations and assuming a body weight of 70 kg for humans, the Cl and Vss for N-nitrosodimethylamine in humans are estimated to be 3450 ml/min and 64,800 ml, respectively.

  1. Efeitos de concentrações crescentes de lidocaína hiperbárica, administradas no espaço subaracnóideo, sobre a medula espinhal e as meninges: estudo experimental em cães Efectos de concentraciones crecientes de lidocaína hiperbara, administradas en el espacio subaracnoideo, sobre la médula espinal y las meninges: estudio experimental en perros Effects of increasing spinal hyperbaric lidocaine concentrations on spinal cord and meninges: experimental study in dogs

    Directory of Open Access Journals (Sweden)

    Silvânia R.O. Pires

    2006-06-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Ainda não está bem estabelecida a concentração de lidocaína que é potencialmente capaz de determinar lesão no tecido nervoso. O objetivo desta pesquisa foi estudar os efeitos sobre a medula espinhal e as meninges, de concentrações crescentes de lidocaína administrada por via subaracnóidea, em injeção única através de agulha de Quincke. MÉTODO: Após a aprovação da Comissão de Ética em Experimentação Animal, 40 cães adultos foram anestesiados com fentanil e etomidato e submetidos a punção subaracnóidea com agulha de Quincke 22G 21/2 para introdução de 1 mL, em 10 segundos, de solução glicosada a 7,5% - Grupo 1; lidocaína a 5% em solução glicosada a 7,5% - Grupo 2; lidocaína a 7,5% em solução glicosada a 7,5% - Grupo 3; lidocaína a 10% em solução glicosada a 7,5% - Grupo 4. Após a recuperação da anestesia venosa, foram observados, no período em que os animais estavam em vigência do bloqueio subaracnóideo, a presença de bloqueio motor, o tônus do esfíncter anal (normal ou relaxado e o nível de bloqueio sensitivo nos diferentes dermátomos das regiões cervical, torácica, lombar e sacral. Os animais permaneceram em cativeiro por 72 horas. Foram avaliados o tônus do esfíncter anal, a motricidade das patas posteriores, a sensibilidade dolorosa nas patas anteriores e posteriores e nos dermátomos sacrais, lombares e torácicos. Após serem sacrificados por eletrocussão sob anestesia, foram retiradas porções lombar e sacral da medula espinhal e das meninges para exame histológico por microscopia óptica. RESULTADOS: Nenhum animal dos Grupos 1 e 2 apresentou lesões clínicas ou histológicas. Três animais do Grupo 3 apresentaram alterações motoras nas patas posteriores e relaxamento do esfíncter anal. Nestes, foram observados focos de necrose na região posterior (dois cães e necrose em faixa em toda a superfície medular (um cão. Em um outro animal deste grupo, no

  2. A Computational Growth Model for Measuring Dynamic Cortical Development in the First Year of Life

    Science.gov (United States)

    Nie, Jingxin; Li, Gang; Wang, Li; Gilmore, John H.; Lin, Weili

    2012-01-01

    Human cerebral cortex develops extremely fast in the first year of life. Quantitative measurement of cortical development during this early stage plays an important role in revealing the relationship between cortical structural and high-level functional development. This paper presents a computational growth model to simulate the dynamic development of the cerebral cortex from birth to 1 year old by modeling the cerebral cortex as a deformable elastoplasticity surface driven via a growth model. To achieve a high accuracy, a guidance model is also incorporated to estimate the growth parameters and cortical shapes at later developmental stages. The proposed growth model has been applied to 10 healthy subjects with longitudinal brain MR images acquired at every 3 months from birth to 1 year old. The experimental results show that our proposed method can capture the dynamic developmental process of the cortex, with the average surface distance error smaller than 0.6 mm compared with the ground truth surfaces, and the results also show that 1) the curvedness and sharpness decrease from 2 weeks to 12 months and 2) the frontal lobe shows rapidly increasing cortical folding during this period, with relatively slower increase of the cortical folding in the occipital and parietal lobes. PMID:22047969

  3. The essential oil qualitative and quantitative composition in the needles of Pinus sylvestris L. growing along industrial transects

    Energy Technology Data Exchange (ETDEWEB)

    Kupcinskiene, Eugenija [Department of Biology, Vytautas Magnus University, Vileikos 8, LT-44404 Kaunas (Lithuania)], E-mail: e.kupcinskiene@gmail.com; Stikliene, Aida [Department of Ecology, Lithuanian University of Agriculture, Studentu 11, LT-53361 Kaunas, Akademija (Lithuania); Judzentiene, Asta [Institute of Chemistry, A. Gostauto 9, LT-01108 Vilnius (Lithuania)

    2008-10-15

    The aim of this study was to evaluate composition of the essential oils in the needles of Pinus sylvestris growing in the areas affected by a cement factory (CF), and an oil refinery (OR). Volatile components of the needles were analyzed by GC and GC/MS. The most heavily polluted CF stand had significantly higher concentration of {gamma}-Terpinene, Caryophyllene oxide in the current-year needles, while higher concentration of {delta}-3-Carene, {alpha}-Terpinene, {gamma}-Terpinene and Terpinolene was documented for 1-year-old needles. The most heavily polluted OR stand had a significantly higher concentration of Sabinene + {beta}-Pinene, 1-epi-Cubenol in the current-year needles and a significantly higher concentration of Camphene, Sabinene + {beta}-Pinene, Myrcene, {alpha}-Cadinene, 1-epi-Cubenol in the 1-year-old needles than the least polluted site. Along transects an increase in the amount of some diterpenes and a decrease in the components of the shorter chain essential oils was observed. These effects could be at least partially attributed to SO{sub 2}. - Quantities of components of essential oil in the needles of Scots pine growing around two factories are described in relation to pollution.

  4. Consumers’ perception and knowledge of food safety: results of questionnaires accessible on IZSalimenTO website

    Directory of Open Access Journals (Sweden)

    Amaranta Traversa

    2015-04-01

    Full Text Available The present survey was undertaken to investigate consumers’ knowledge of the main foodborne agents and dietary regimen during pregnancy. Data were collected using monthly questionnaires available on IZSalimenTO website between March 2013 and January 2014. Hepatitis A virus questionnaire: 20 respondents (77% recognized berries as foodstuff linked to the outbreak of hepatitis A. The majority correctly indicated as precautionary advice to boil berries before consumption. Botulism questionnaire: 29 respondents (62% indicated pesto as food involved in botulism alert in July 2013. The risk of infant botulism in infant less than 1 year old due to honey consumption is known by 24 respondents (51%. Main foodborne disease questionnaire: the risk of infection by Salmonella after the consumption of foods made with raw eggs is known by the majority (94%; N=17 as well as the treatments to be applied in order to make fresh fish safe from parasites (76%. Pregnancy questionnaire: 20 respondents (74% believed that washing vegetables and fruits with sodium bicarbonate or chlorate solution is able to inactivate Toxoplasma; only 4 (15% reported both raw meat and vegetables washed with sodium bicarbonate as food at risk. Results indicate that all consumers should be trained on behaviour and dietary regimen to be adopted in pregnancy and in infant <1 year old. The website may be considered as a useful tool to assess consumers’ knowledge: both the news section and the contents published may be a source of information and education for consumers on food safety.

  5. 1- and 2-year-olds' expectations about third-party communicative actions.

    Science.gov (United States)

    Thorgrimsson, Gudmundur B; Fawcett, Christine; Liszkowski, Ulf

    2015-05-01

    Infants expect people to direct actions toward objects, and they respond to actions directed to themselves, but do they have expectations about actions directed to third parties? In two experiments, we used eye tracking to investigate 1- and 2-year-olds' expectations about communicative actions addressed to a third party. Experiment 1 presented infants with videos where an adult (the Emitter) either uttered a sentence or produced non-speech sounds. The Emitter was either face-to-face with another adult (the Recipient) or the two were back-to-back. The Recipient did not respond to any of the sounds. We found that 2-, but not 1-year-olds looked quicker and longer at the Recipient following speech than non-speech, suggesting that they expected her to respond to speech. These effects were specific to the face-to-face context. Experiment 2 presented 1-year-olds with similar face-to-face exchanges but modified to engage infants and minimize task demands. The infants looked quicker to the Recipient following speech than non-speech, suggesting that they expected a response to speech. The study suggests that by 1 year of age infants expect communicative actions to be directed at a third-party listener.

  6. Population density influences dispersal in female white-tailed deer

    Science.gov (United States)

    Lutz, Clayton L.; Diefenbach, Duane R.; Rosenberry, Christopher S.

    2015-01-01

    Dispersal behavior in white-tailed deer (Odocoileus virginianus) predominantly occurs in 1-year-old males; however, females of the same age also disperse. The timing of female dispersal during fawning season and low dispersal rates suggest that competition for mates and reduced inbreeding are not ultimate causes of female dispersal, as suggested for males. We proposed that female dispersal is the result of competition for space when pregnant females seek to isolate themselves before and after parturition. To test this hypothesis, we conducted a meta-analysis of female dispersal rates from 12 populations of white-tailed deer and predicted dispersal rate and distance were positively related to deer density. We found a positive relationship between dispersal rate and deer per forested km2 and between dispersal distance and deer per forested km2. These results are consistent with the hypothesis that female dispersal is density-dependent and caused by the exclusion of subordinate 1-year-olds as adult females seek isolation before and after parturition.

  7. Influence of Pneumococcal Conjugate Vaccine on Acute Otitis Media with Severe Middle Ear Inflammation: A Retrospective Multicenter Study.

    Science.gov (United States)

    Sugino, Hirotoshi; Tsumura, Shigeru; Kunimoto, Masaru; Noda, Masuhiro; Chikuie, Daisuke; Noda, Chieko; Yamashita, Mariko; Watanabe, Hiroshi; Ishii, Hidemasa; Tashiro, Toru; Iwata, Kazuhiro; Kono, Takashi; Tsumura, Kaoru; Sumiya, Takahiro; Takeno, Sachio; Hirakawa, Katsuhiro

    2015-01-01

    The Japanese guidelines for acute otitis media in children recommend classifying acute otitis media by age, manifestations and local findings, and also recommend myringotomy for moderate-grade cases with severe local findings, severe-grade cases, and treatment-resistant cases. The heptavalent pneumococcal conjugate vaccine was released in Japan in February 2010. In Hiroshima City, public funding allowing free inoculation with this vaccine was initiated from January 2011, and the number of vaccinated individuals has since increased dramatically. This study investigated changes in the number of myringotomies performed to treat acute otitis media during the 5-year period from January 2008 to December 2012 at two hospitals and five clinics in the Asa Area of Hiroshima City, Japan. A total of 3,165 myringotomies for acute otitis media were performed. The rate of procedures per child-year performed in acute otitis media in 1-year-old infants decreased significantly in the 2 years after the introduction of public funding for heptavalent pneumococcal conjugate vaccine compared to all years before introduction (pacute otitis media in reducing the financial burden of myringotomy. In addition, this vaccine may help prevent acute otitis media with severe middle ear inflammation in 1-year-old infants.

  8. Between-country comparison of whole-body SAR from personal exposure data in Urban areas.

    Science.gov (United States)

    Joseph, Wout; Frei, Patrizia; Röösli, Martin; Vermeeren, Günter; Bolte, John; Thuróczy, György; Gajšek, Peter; Trček, Tomaž; Mohler, Evelyn; Juhász, Péter; Finta, Viktoria; Martens, Luc

    2012-12-01

    In five countries (Belgium, Switzerland, Slovenia, Hungary, and the Netherlands), personal radio frequency electromagnetic field measurements were performed in different microenvironments such as homes, public transports, or outdoors using the same exposure meters. From the mean personal field exposure levels (excluding mobile phone exposure), whole-body absorption values in a 1-year-old child and adult male model were calculated using a statistical multipath exposure method and compared for the five countries. All mean absorptions (maximal total absorption of 3.4 µW/kg for the child and 1.8 µW/kg for the adult) were well below the International Commission on Non-Ionizing Radiation Protection (ICNIRP) basic restriction of 0.08 W/kg for the general public. Generally, incident field exposure levels were well correlated with whole-body absorptions (SAR(wb) ), although the type of microenvironment, frequency of the signals, and dimensions of the considered phantom modify the relationship between these exposure measures. Exposure to the television and Digital Audio Broadcasting band caused relatively higher SAR(wb) values (up to 65%) for the 1-year-old child than signals at higher frequencies due to the body size-dependent absorption rates. Frequency Modulation (FM) caused relatively higher absorptions (up to 80%) in the adult male.

  9. Seasonal intermittent preventive treatment for the prevention of anaemia and malaria in Ghanaian children: a randomized, placebo controlled trial.

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    Margaret Kweku

    Full Text Available BACKGROUND: Malaria and anaemia are the leading causes of morbidity and mortality in children in sub-Saharan Africa. We have investigated the effect of intermittent preventive treatment with sulphadoxine-pyrimethamine or artesunate plus amodiaquine on anaemia and malaria in children in an area of intense, prolonged, seasonal malaria transmission in Ghana. METHODS: 2451 children aged 3-59 months from 30 villages were individually randomised to receive placebo or artesunate plus amodiaquine (AS+AQ monthly or bimonthly, or sulphadoxine-pyrimethamine (SP bimonthly over a period of six months. The primary outcome measures were episodes of anaemia (Hb1 year old when they received IPTc compared to the placebo group. However the incidence of malaria in the post intervention period was higher in children who were <1 year old when they received AS+AQ monthly compared to the placebo group. INTERPRETATION: IPTc is safe and efficacious in reducing the burden of malaria in an area of Ghana with a prolonged, intense malaria transmission season. TRIAL REGISTRATION: ClinicalTrials.gov NCT00119132.

  10. Response to seasonal drought in three cultivars of Ceratonia siliqua: leaf growth and water relations.

    Science.gov (United States)

    Correia, M J; Coelho, D; David, M M

    2001-07-01

    Responses of leaf growth and leaf water relations to seasonal drought were monitored during two successive years in three cultivars (Galhosa, Espargal and Mulata) of Ceratonia siliqua L. growing in the field in southern Portugal. Leaf water relations of fully expanded leaves were characterized by pressureâ volume analysis, and morphometric measurements of petiolar xylem were made. The three cultivars differed with respect to onset of leaf initiation. In Galhosa, there was a sharp peak of leaf initiation in June that was immediately followed by a period when leaf expansion rates were highest. The onset of leaf growth occurred earlier in Espargal and Mulata than in Galhosa, and both cultivars continued producing new leaves throughout the summer period. The diurnal pattern of water relations in recently expanded leaves indicated that, during midsummer, Galhosa was the only cultivar in which leaf water potential did not fall below the turgor loss point and leaf relative water content remained above 90%. The occurrence of osmotic adjustment in recently expanded leaves of Galhosa was not demonstrated conclusively. However, during the dry season following leaf formation, a seasonal decrease in osmotic potential sufficient to maintain turgor was detected in 1-year-old leaves of Galhosa but not in 1-year-old leaves of the other cultivars. Among cultivars, Galhosa petioles had the widest xylem conduits, which may partly explain why midday leaf water potential in Galhosa never decreased below -2.0 MPa even at the end of the summer drought.

  11. Uptake and translocation of 54Mn and 65Zn applied on foliage and bark surfaces on balsam fir (Abies balsamea (L.) Mill.) seedlings

    International Nuclear Information System (INIS)

    Uptake and translocation of 54Mn and 65Zn in balsam fir [Abies balsamea (L.) Mill.] seedlings were studied with the radioisotopes applied directly on shoot or main-stem surfaces in a growth chamber. Concentration and distribution of the absorbed radioisotopes in different plant parts depended on distances between source (the application site) and sink (the rest of the seedling), as well as on tissue growth activity. Acidic wetness significantly enhanced radioisotope absorption. 54Mn and 65Zn were found to be concentrated primarily in 1-year old needles at the middle and top levels of the seedling crown. There were significant (P < 0.05) differences in accumulation (Bq g−1) between 54Mn and 65Zn in needles and twigs from foliar uptake. The absorption by seedlings (including the washed application shoot) 70 days after application was 24–32% of the remaining activities for 54Mn and 25–30% for 65Zn. Less than 1% of the absorbed isotopes was translocated from the bark application sites to other plant organs, whereas more than 54% of the activity absorbed at 1-year old shoots moved to the rest of the seedling. (author)

  12. Hepatopatía crónica asociada a fibrosis quística: gasto energético en reposo, factores de riesgo y repercusión en la evolución de la enfermedad Chronic liver disease associated with cystic fibrosis: energy expended at rest, risk factors and impact on the disease's progress

    Directory of Open Access Journals (Sweden)

    S. Tabernero da Veiga

    2004-02-01

    Full Text Available Introducción y objetivos: La fibrosis quística es la enfermedad recesiva más frecuente. Existen diferentes alteraciones hepatobiliares; la más importante es el desarrollo de obstrucción biliar y fibrosis periportal. El objetivo es valorar la influencia de la hepatopatía en el estado nutricional, la evolución de la enfermedad y los factores de riesgo asociados. Ámbito: Unidad de Nutrición del Servicio de Gastroenterología del Hospital Infantil La Paz. Material y métodos: Estudio longitudinal prospectivo con 53 pacientes valorados en tres momentos durante 3 años; al inicio, al año y a los 3 años. Solo 37 se siguieron los 3 años. Se realizan 111 mediciones que incluyen: análisis de la composición corporal, del gasto energético, de la ingesta y de las pérdidas energéticas así como balance nitrogenado. Simultáneamente se realizan pruebas de función respiratoria y se valora la presencia de reagudización respiratoria. Resultados: 37 pacientes, 19 mujeres y 18 varones (edad media 13,04 años ± 3,28. Doce (32,43% fueron diagnosticados de hepatopatía (edad media 12,16 años ± 3,86 DS, 11 varones, 1 mujer de los cuales 1 presentó íleo meconial, 5 eran homocigotos, 5 heterocigotos y los 2 restantes presentaban otras mutaciones. Los hepatópatas presentan parámetros antropométricos mejores o similares que los pacientes sin hepatopatía (p NS. Media del índice de Waterlow en hepatópatas: 93,62% ± 7,87 DS; no hepatópatas: 93,06% ± 10,97 DS (p NS. Media de FEV1 en hepatópatas: 88,81 ± 27,32 DS; no hepatópatas: 75,21 ± 27,92 DS (p Introduction and goals: Cystic fibrosis is the most frequent recessive disease. There are various hepato-biliary alterations, of which the most important is the development of biliary obstruction and periportal fibrosis. The goal is to assess the influence of liver disease on the nutritional status, the progress of the disease and the associated risk factors. Scope: Nutrition Unit of the

  13. Atrial – Ventricular Septal Defect

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    T Panagiotopoulos

    2009-05-01

    Full Text Available Atrial and ventricular septal defect constitute the most common congenital heart disease.Aim: Τhe aim of the present retrospective study was to record data and factors that affect atrial and ventricular septal defect.Method and material: The sample study included patients of both sexes who were hospitalized with diagnosis atrial and ventricular septal defect in a Cardiac Surgery hospital of Athens. A specially constructed printed form was used for data collection, where were recorded the demographic and personal variables, the pathological, surgical, cardiology and obstetric history, the habits of adults, as well as the personal characteristics of mothers. Analysis of data was performed by descriptive statistical analysis.Results: The sample study consisted of 101 individuals with diagnosis atrial or ventricular Septal Defect, of which 40% were boys and 60% girls. The 70% of the sample study suffered from atrial Septal Defect and the 30% suffered from ventricular Septal Defect. Regarding age, 12% of the sample study was 0-1 years old, 35% was >1 years old, 8% was >12-18 years old and 45% over than 18 years old. Regarding educational status of the adult participants, 9% was of 0-6 years education, 22%>6 -12 years, 13%>12 years. 14% of the adult paticipants smoked, 4% consumed alcohol and 5% smoked in conjunction with alcohol. In terms of the obstetric history of the sample studied, 32% of the cases had normal birth, 4% had a twin birth and 1% had a triplet one. According to the variables related to mothers, the mean age of the mother was 30 years and 3 months, 10% were smokers at pregnancy and 3% used chemical substance and mainly hair color. Also, the results of the present study showed that individuals of 12-18 and >18 years old did not suffer from ventricular Septal Defect, whereas the infants 0-1 years old did not suffer from Atrial Septal Defect. The mean value of age at the admission in intensive care unit was 7 months (12% for the infants

  14. Effects of GHRP-2 and Cysteamine Administration on Growth Performance, Somatotropic Axis Hormone and Muscle Protein Deposition in Yaks (Bos grunniens) with Growth Retardation

    Science.gov (United States)

    Hu, Rui; Wang, Zhisheng; Peng, Quanhui; Zou, Huawei; Wang, Hongze; Yu, Xiaoqiang; Jing, Xiaoping; Wang, Yixin; Cao, Binghai; Bao, Shanke; Zhang, Wenhua; Zhao, Suonan; Ji, Hanzhong; Kong, Xiangying; Niu, Quanxi

    2016-01-01

    The objective of this study was to investigate the effects of growth hormone-releasing peptide-2 (GHRP-2) and cysteamine (CS) administration on growth performance in yaks with growth retardation and try to elucidate its regulatory mechanisms. Trial 1, thirty-six 1-year-old Qinghai high plateau yaks (body weight 38–83.2 kg) were randomly chosen for body weight and jugular blood samples collection. The relationship between body weight and serum GHRH (P < 0.05, R = 0.45), GH (P < 0.05, R = 0.47), IGF-1 (P < 0.05, R = 0.62) was significantly correlated in yaks colonies with lighter body weights. Trial 2, fifteen 1-year-old Qinghai high plateau yaks with growth retardation (average body weight 54.8 ± 8.24 kg) were randomly selected and assigned to negative control group (NG), GHRP-2 injection group (GG) and cysteamine feeding group (CG), with 5 yaks per group. Another five 1-year-old Qinghai high plateau yaks with normal growth performance (average body weight 75.3 ± 2.43 kg) were selected as positive control group (PG). The average daily gain (ADG) of the GG and CG were significantly higher than those in the PG and NG (P < 0.05). Both GHRP-2 and CS administration significantly enhanced the myofiber diameter and area of skeletal muscle (P<0.05). GHRP-2 significantly enhanced the serum GH and IGF-1 levels (P < 0.05), and up-regulated GHR, IGF-1 and IGF-1R mRNA expression in the liver and skeletal muscle (P < 0.05), enhanced the mRNA expression of PI3K, AKt and mTOR in the skeletal muscle (P<0.05). CS significantly reduced the serum SS levels and the hypothalamus SS mRNA expression (P < 0.05), and enhanced GHR and IGF-1 mRNA expression in the liver (P < 0.05), decreased the mRNA expression of muscle atrophy F-box (Atrogin-1) and muscle ring finger 1 (MuRF1) mRNA (P < 0.05). Conclusions: Growth retardation in yaks was primarily due to somatotropic axis hormones secretion deficiency. Both GHRP-2 and CS administration can accelerate growth performance and GH, IGF-1

  15. CO2 uptake of Opuntia ficus-indica (L. Mill. whole trees and single cladodes, in relation to plant water status and cladode age

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    Giorgia Liguori

    2013-02-01

    Full Text Available Most of net photosynthesis determinations in Opuntia ficus-indica come from measurements on individual cladodes. However, they have limitations when used to scale up to whole canopy gas exchange, because a large variability of carbon assimilation may occur within the canopy, due to, among others, differences in cladode age and intercepted radiation or individual cladode response to abiotic stresses. The aim of this work was to evaluate the application of open gas exchange chambers, simultaneously applied around the whole canopy, to measure net CO2 uptake, continuously over a 24 h period, in single Opuntia ficus-indica (L. Mill. potted trees and in relation with their water status. Net CO2 uptake was also measured for single cladodes differentiated by age. O. ficus-indica trees continued their photosynthetic activity 60 days after the irrigation was stopped, when soil water content was lower than 5%. At this stage, current-year and 1-year-old cladodes had become flaccid but still the daily net CO2 uptake of non-irrigated trees kept the same rate than at the beginning of the experiment, while watered trees had doubled their net CO2 uptake. The highest instantaneous rates and total daily net CO2 uptake for both well-watered and non-irrigated trees occurred 60 days after the onset of the dry period, when maximal instantaneous rates were 11.1 in well-watered trees and 8.4 mol m–2 s–1 in non-irrigated trees. During the drought period, the chlorenchyma fresh weight decreased by 45% and 30%, in 1- and 2-yearold drought cladodes respectively, and marginally increased in currentyear ones (+20%. Net CO2 uptake for 1-year-old and 2-year-old cladodes changed only at highest photosynthetic photon flux density and temperatures, and average seasonal net CO2 uptake of 2-year-old cladodes was 15% lower than for 1-year-old ones. Whole-tree gas exchange measurements applied for the first time to O. ficus-indica indicated that whole cactus pear trees maintain

  16. Changes in phytochemical synthesis, chalcone synthase activity and pharmaceutical qualities of sabah snake grass (Clinacanthus nutans L.) in relation to plant age.

    Science.gov (United States)

    Ghasemzadeh, Ali; Nasiri, Alireza; Jaafar, Hawa Z E; Baghdadi, Ali; Ahmad, Izham

    2014-01-01

    In the current study, changes in secondary metabolite synthesis and the pharmaceutical quality of sabah snake grass leaves and buds were considered in relation to plant age (1 month, 6 months, and 1 year old). The activity of the enzyme chalcone synthase (CHS, EC 2.3.1.74) was measured, as it is a key enzyme for flavonoid production. Significant differences in total flavonoid (TF) production were observed between the three plant growth periods and the different plant parts. The highest contents of TF (6.32 mg/g dry weight [DW]) and total phenolic (TP) (18.21 mg/g DW) were recorded in 6-month-old buds. Among the flavonoids isolated in this study the most important ones based on concentration were from high to low as follows: catechin > quercetin > kaempferol > luteolin. Production of phenolic acids increased from 1 to 6 months, but after 6 months up to 1 year of age, they decreased significantly. The highest contents of caffeic acid (0.307 mg/g DW) and gallic acid (5.96 mg/g DW) were recorded in 1-year and 6-month-old buds, respectively. The lowest and highest activity of CHS was recorded in 1-month and 6-month-old buds with values of 3.6 and 9.5 nkat/mg protein, respectively. These results indicate that the increment in flavonoids and phenolic acids in 6-month-old buds can be attributed to an increase in CHS activity. The highest 1,1-diphenyl-2-picrylhydrazyl (DPPH) activity was observed in the extract of 1-year-old buds followed by 6-month-old buds, with 50% of free radical scavenging (IC50) values of 64.6 and 73.5 µg/mL, respectively. Interestingly, a ferric reducing antioxidant power (FRAP) assay showed a higher activity in 6-month-old buds (488 μM of Fe(II)/g) than in 1-year-old buds (453 μM of Fe(II)/g), in contrast to the DPPH result. Significant correlations (p < 0.05) were observed between CHS enzyme activity and FRAP activity, TF, catechin, and kaempferol content. Extracts of 6-month-old bud exhibited a significant in vitro anticancer activity against

  17. Changes in Phytochemical Synthesis, Chalcone Synthase Activity and Pharmaceutical Qualities of Sabah Snake Grass (Clinacanthus nutans L. in Relation to Plant Age

    Directory of Open Access Journals (Sweden)

    Ali Ghasemzadeh

    2014-10-01

    Full Text Available In the current study, changes in secondary metabolite synthesis and the pharmaceutical quality of sabah snake grass leaves and buds were considered in relation to plant age (1 month, 6 months, and 1 year old. The activity of the enzyme chalcone synthase (CHS, EC 2.3.1.74 was measured, as it is a key enzyme for flavonoid production. Significant differences in total flavonoid (TF production were observed between the three plant growth periods and the different plant parts. The highest contents of TF (6.32 mg/g dry weight [DW] and total phenolic (TP (18.21 mg/g DW were recorded in 6-month-old buds. Among the flavonoids isolated in this study the most important ones based on concentration were from high to low as follows: catechin > quercetin > kaempferol > luteolin. Production of phenolic acids increased from 1 to 6 months, but after 6 months up to 1 year of age, they decreased significantly. The highest contents of caffeic acid (0.307 mg/g DW and gallic acid (5.96 mg/g DW were recorded in 1-year and 6-month-old buds, respectively. The lowest and highest activity of CHS was recorded in 1-month and 6-month-old buds with values of 3.6 and 9.5 nkat/mg protein, respectively. These results indicate that the increment in flavonoids and phenolic acids in 6-month-old buds can be attributed to an increase in CHS activity. The highest 1,1-diphenyl-2-picrylhydrazyl (DPPH activity was observed in the extract of 1-year-old buds followed by 6-month-old buds, with 50% of free radical scavenging (IC50 values of 64.6 and 73.5 µg/mL, respectively. Interestingly, a ferric reducing antioxidant power (FRAP assay showed a higher activity in 6-month-old buds (488 μM of Fe(II/g than in 1-year-old buds (453 μM of Fe(II/g, in contrast to the DPPH result. Significant correlations (p < 0.05 were observed between CHS enzyme activity and FRAP activity, TF, catechin, and kaempferol content. Extracts of 6-month-old bud exhibited a significant in vitro anticancer activity

  18. Gangliosideos e a resposta de hipersensibilidade retardada em camundongos

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    EFS MONTERO

    2000-01-01

    Full Text Available Em trabalhos anteriores mostrou-se que os gangliosídeos (GSLs têm um efeito inibitório sobre a proliferação linfocitária e a síntese de IL-2, assim como sobre a reação mista de linfócitos. Neste estudo objetivou-se avaliar o efeito dos GSLs sobre a resposta de hipersensibilidade retardada. Foram utilizados 12 camundongos BALB/c, machos, pesando em média 30 gramas, provenientes do biotério setorial da Disciplina de Parasitologia e mantidos por 5 dias para adaptação no biotério setorial da Disciplina de Técnica Operatória e Cirurgia Experimental da UNIFESP-EPM, recebendo água e ração própria para a espécie. Os animais foram distribuídos em três grupos, de acordo com as doses de GSLs, da seguinte forma: grupo 3mg. kg-1, grupo 9mg. kg-1 e grupo simulado (veículo. Os animais foram tratados, por via intramuscular, nos dias 0 e 4. O parâmetro avaliado foi o edema da pata traseira esquerda no local da inoculação do antígeno. Os animais foram anestesiados com Cetamina (60mg.kg-1 e Xilazina (10mg.kg-1, por via intramuscular, sendo em seguida submetidos à dissecção da veia jugular direita, por onde foram inoculadas 10(6 hemácias de Carneiro no dia 0, para sensibilização. No dia 4 subsequente, os animais foram novamente anestesiados e receberam, por via subcutânea, 10(8 hemácias de Carneiro, num volume de 0,02ml. Foram realizadas medidas do edema da pata traseira com paquímetro 24, 48, 72 e 96 horas após o desafio. Os dados mostraram que após 48h houve um aumento do edema em animais dos grupos simulado e 3mg (médias=2,3 and 2,1mm, respectivamente, e os camundongos do grupo 9mg não apresentaram aumento importante (média=0,1mm. Entretanto, após 72h, o grupo 9mg apresentou aumento de 1,7mm enquanto, os outros grupos não apresentaram mudança significativa no edema da pata (médias=0,2 e 0,8mm, grupos simulado e 3mg, respectivamente comparados aos dados do dia antecedente. Após 96h, todos os grupos apresentaram

  19. Delincuente sexual en serie y alteraciones psicopáticas: una relación ocasional Repeat sex offender and psychopathic changes: An incidental relationship

    Directory of Open Access Journals (Sweden)

    M. Ventura Alvarez

    2003-04-01

    Full Text Available Los delincuentes sexuales en serie son tomados frecuentemente como psicópatas, en parte como consecuencia de la creciente popularidad del término. Un delincuente sexual en serie es aquel que ha actuado sobre dos o más víctimas en diferentes fechas; un psicópata es un tipo de trastorno de la personalidad que exhibe un patrón duradero de conductas socialmente irresponsables que desprecian los derechos de los demás. El presente trabajo presenta un caso de violador en serie interrumpido precozmente gracias a la actuación policial. Desde la óptica de su modus operandi lo consideramos dentro de los que Nicholas Groth denomina violador "confirmador de poder" y, tras su estudio clínico y psicométrico, no obtuvimos ningún dato que nos indujera a pensar que nos encontrábamos ante un psicópata. Revisamos ambos perfiles, los de psicopatía y los de agresor sexual en serie. Coincidimos con Marshall en la dificultad de caracterizar la personalidad del delincuente sexual y extraemos estudios como los de Quinsey y Malcolm, quienes encuentran, respectivamente, un 30% y un 7,5 % de psicopatías entre los delincuentes sexuales presos. Llamamos la atención sobre la relación poco clara entre la psicopatía y esta modalidad delictiva. Muchos de los estudios norteamericanos se han limitado a establecer patrones de comportamiento clasificatorios en función de la victimología, motivos o modo de operar de los agresores, muy útiles para las líneas de investigación policial, pero poco reveladores para el psiquiatra forense. Posiblemente no exista un claro patrón de personalidad debajo de la conducta de un violador, pero lamentamos la escasa producción científica al respecto.Repeat sex offenders are often taken for psychopaths, partly due to the increasing popularity of the term. A repeat sex offender is one who has had one or more victims at different times; a psychopath is a type of personality imbalance which displays a lasting pattern of socially

  20. Anti-inflammatory and toxicity studies of atranorin extracted from Cladina kalbii Ahti in rodents

    Directory of Open Access Journals (Sweden)

    Marcelia Garcez Dória de Melo

    2011-12-01

    Full Text Available Atranorin (ATR is the main compound from the lichen Cladina kalbii Ahti, which grows in the arid regions of northeastern Brazil. This study was conducted to evaluate the anti-inflammatory and toxicological properties of ATR. To evaluate anti-inflammatory properties, paw edema was induced by injecting 0.1 mL of carrageenan into the subplantar region of the right hind paw of rats, and leukocyte migration was induced by injection of 500 µL of carrageenan into the peritoneal cavity of mice. In addition, we determined ATR cytotoxicity in L929 cells by MTT assay and acute (5 g/kg-single dose and subchronic (50 mg/kg-30 days toxicity tests in Wistar rats. The results showed that ATR (100 mg/kg and 200 mg/kg exhibited significant anti-inflammatory activity (paw edema and leukocyte migration. In the acute toxicity test, the animals showed hypoactivity and lethargy during the initial period (first 6 hours and increase in total protein, total and indirect bilirubin, and alkaline phosphatase after 14 days in ATR-treated male rats. The subchronic toxicity test revealed increases in total protein, globulin, gamma-glutamyl transferase, alkaline phosphatase, and total and direct bilirubin in ATR-treated female rats. Histological analysis revealed no changes in the architecture and morphology of the organs. These results suggest that ATR has significant anti-inflammatory activity, with no significant acute and subchronic toxicity or cytotoxicity.Atranorina (ATR é o principal composto do líquen Cladina kalbii Ahti, que cresce em terras áridas do nordeste brasileiro. Este estudo foi realizado para avaliar as propriedades antiinflamatórias e toxicológicas da ATR. Para avaliar as propriedades antiinflamatórias, o edema de pata foi induzido, administrando-se 0,1 mL de carragenina na região subplantar da pata traseira direita e a migração leucocitária foi induzida pela injeção de 500 µL de carragenina no peritônio. Além disso, determinou-se a

  1. TWO-STAGE SURGICAL TREATMENT OF A CHILD OF ONE YEAR FROM CONGENITAL HEART DISEASE AND BILIARY CIRRHOSIS

    Directory of Open Access Journals (Sweden)

    S. V. Gautier

    2014-01-01

    Full Text Available Aim: Clinical case of successful two-stage surgical treatment of a 1-year-old child with congenital heart disease and biliary cirrhosis is represented in this article. At the first day of life laparotomy was performed because of high intestinal obstruction. Kasai procedure and Roux-en-Y choledochojejunostomy were per- formed on 12th day and at the end of second month of life, respectively. Liver biopsy showed the signs of biliary cirrhosis. At the same time ventricular septal defect and atrial septal defect with pulmonary hyper- tension were diagnosed. The first step of treatment was the surgical septal defects closure. No complications during procedure, cardiopulmonary bypass and post-operative period were registered. There were no nega- tive effects on liver function after cardiac surgery. 11 months later living-donor liver transplantation was performed without any complications. Patient was discharged at 35th post-transplant day with stable graft function. 

  2. Feed intake, digestibility, nitrogen utilization, and body weight change of sheep consuming wheat straw supplemented with local agricultural and agro-industrial by-products.

    Science.gov (United States)

    Nurfeta, Ajebu

    2010-06-01

    Effects of supplementing sheep consuming wheat straw with local agro-industrial by-products on feed intake, growth, digestibility and nitrogen utilization were determined. Thirty 1-year-old local wethers, with a mean (+/-SD) live weight of 19.8 (+/-1.06) kg, were assigned to five treatments: wheat straw + atella (T1), wheat straw + atella + poultry litter (T2), wheat straw + atella + coffee pulp (T3), wheat straw + atella + coffee pulp + poultry litter (T4), hay + concentrate (T5). A 7-day digestibility experiment and a 112-day growth trial were conducted. Total dry matter (DM) and organic matter (OM) intake as well as body weight gain was similar for all treatments. The highest (P coffee pulp are available, smallholder farmers could feed the mixtures as a supplement to straw with a good performance without using concentrate feeds.

  3. Changes in the Essential Oil Composition in the Needles of Scots Pine (Pinus sylvestris L. Under Anthropogenic Stress

    Directory of Open Access Journals (Sweden)

    Asta Judzentiene

    2007-01-01

    Full Text Available Unfavorable anthropogenic factors, such as air pollution, lead to biochemical responses in trees. Changes in the amounts of secondary metabolites may be early indicators of invisible injuries. The aim of this study was to evaluate composition of the essential oils in the needles of Scots pine (Pinus sylvestris L. growing in the areas affected by pollutant emissions of main factories in Lithuania: a nitrogen fertilizer factory (NFF, a cement factory (CF, and an oil refinery (OR. Totally, 14 pine stands were examined along transects from the factories (July 2005. Volatile components of the needles were extracted and analyzed by GC and GC/MS. Over 70 components of the essential oils were identified in current-year and 1-year-old needles.

  4. A preliminary assessment of individual doses in the environs of Berkeley, Gloucestershire, following the Chernobyl nuclear reactor accident

    International Nuclear Information System (INIS)

    A preliminary assessment has been made of the individual doses to critical group members of the public in the environs of Berkeley arising from fallout resulting from the Chernobyl accident. The assessment was based on measurements of airborne radionuclide concentrations, ground deposition and nuclide concentrations in rainwater, tapwater, grass, milk and green vegetables. The committed effective dose-equivalent was found to be as follows:- Adult - 200 μSv, 1 year old child - 500 μSv, the 10 year old child receiving a dose intermediate between these two values. The estimate accounts only for the nuclides measured and the specific exposure routes considered namely ingestion of milk and vegetables, inhalation and external exposure. However, it is believed that the inclusion of a range of other nuclides of potential significance, which may have been present but not measured, and potential intakes from additional routes is unlikely to increase the above estimates by more than a factor of 2. (author)

  5. Infratentorial medulloepithelioma with divergent differentiation: Possibly a predictor of poor outcome

    Directory of Open Access Journals (Sweden)

    Indranil Chakrabarti

    2012-01-01

    Full Text Available Medulloepitheliomas (WHO grade IV are rare, malignant embryonal tumors of pediatric population, classified under the central nervous system (CNS primitive neuroectodermal tumors (PNET. Histologically, these tumors are characterized by neoplastic neuroepithelium recapitulating the embryonic neural tube. We describe a rare case of infratentorial medulloepithelioma with divergent differentiation in a 1-year-old male child who presented with headache, vomiting, and seizures. Histopathologic examination of the excised tumor revealed the characteristic neuroepithelium, along with other areas showing primitive neuroectodermal (blastemal cells in sheets, ependymoblastic rosettes, and nodular areas of neuronal differentiation. Possibly, this proliferating immature neuroepithelium is the cause of poor outcome in medulloepitheliomas. Due to the rarity of these tumors, it remains to be established whether infratentorial location or tumors with divergent differentiation are also predictors of adverse prognosis.

  6. Infratentorial medulloepithelioma with divergent differentiation: Possibly a predictor of poor outcome.

    Science.gov (United States)

    Chakrabarti, Indranil; Majumdar, Kaushik; Giri, Amita

    2012-05-01

    Medulloepitheliomas (WHO grade IV) are rare, malignant embryonal tumors of pediatric population, classified under the central nervous system (CNS) primitive neuroectodermal tumors (PNET). Histologically, these tumors are characterized by neoplastic neuroepithelium recapitulating the embryonic neural tube. We describe a rare case of infratentorial medulloepithelioma with divergent differentiation in a 1-year-old male child who presented with headache, vomiting, and seizures. Histopathologic examination of the excised tumor revealed the characteristic neuroepithelium, along with other areas showing primitive neuroectodermal (blastemal) cells in sheets, ependymoblastic rosettes, and nodular areas of neuronal differentiation. Possibly, this proliferating immature neuroepithelium is the cause of poor outcome in medulloepitheliomas. Due to the rarity of these tumors, it remains to be established whether infratentorial location or tumors with divergent differentiation are also predictors of adverse prognosis.

  7. Nasopharyngeal foreign body triggered by a blind finger sweep.

    Science.gov (United States)

    Mori, Takaaki; Inoue, Nobuaki

    2016-01-01

    A previously healthy 1-year-old boy suddenly began choking and coughing after ingesting a coin. The child's mother attempted to extract the coin by inserting her fingers in his mouth and sweeping the oral cavity. The mother felt the object momentarily with her fingertips but was unable to retrieve it, and brought her son to a local hospital for assistance. The patient was referred to our emergency department (ED) for possible oesophageal obstruction by a foreign body based on the X-ray findings. On arrival at our ED, the child exhibited mild gagging but presented no respiratory symptoms and normal pulmonary examination. The chest X-ray revealed a nasopharyngeal foreign body. The patient was placed under procedural sedation and emergency removal was successfully completed by an otolaryngologist. Subsequently, the patient was discharged without complications. PMID:27605001

  8. Contiguous triple spinal dysraphism associated with Chiari malformation Type II and hydrocephalus: an embryological conundrum between the unified theory of Pang and the unified theory of McLone.

    Science.gov (United States)

    Dhandapani, Sivashanmugam; Srinivasan, Anirudh

    2016-01-01

    Triple spinal dysraphism is extremely rare. There are published reports of multiple discrete neural tube defects with intervening normal segments that are explained by the multisite closure theory of primary neurulation, having an association with Chiari malformation Type II consistent with the unified theory of McLone. The authors report on a 1-year-old child with contiguous myelomeningocele and lipomyelomeningocele centered on Type I split cord malformation with Chiari malformation Type II and hydrocephalus. This composite anomaly is probably due to select abnormalities of the neurenteric canal during gastrulation, with a contiguous cascading impact on both dysjunction of the neural tube and closure of the neuropore, resulting in a small posterior fossa, probably bringing the unified theory of McLone closer to the unified theory of Pang.

  9. Optimization of pediatric chest radiographic images using optical densities ratio

    Energy Technology Data Exchange (ETDEWEB)

    Souza, Rafael T.F.; Miranda, Jose R.A. [Universidade Estadual Paulista Julio de Mesquita Filho (UNESP), Botucatu, SP (Brazil). Inst. de Biociencias de Botucatu; Pina, Diana R. [Faculdade de Medicina de Botucatu (UNESP), Botucatu, SP (Brazil). Hospital das Clinicas. Dept. de Doencas Tropicais e Diagnostico por Imagem; Duarte, Sergio B. [Centro Brasileiro de Pesquisas Fisicas (CBPF/MCT), Rio de Janeiro, RJ (Brazil)

    2011-07-01

    The aim of this study is the optimization of radiographic images for the pediatric patients in the age range between 0 and 1 years old, through Optical Density Ratio (ODR), considering that pediatric patients are overexposed to radiation in the repeated attempts to obtain radiographic images considered of good quality. The optimization of radiographic techniques was carried out with the RAP-PEPP (Realistic Analytical Phantom coupled to homogeneous Phantom Equivalent to Pediatric Patient) phantom in two incubators and one cradle. The data show that the clinical routine radiographic techniques generate low-quality images at up to 18.8% when evaluated by the ODRs, and increases in doses up to 60% when compared to the optimized techniques doses. (author)

  10. Reconstruction of Internal and External Exposures of Fukushima Residents.

    Science.gov (United States)

    Akahane, Keiichi

    2016-09-01

    After the Fukushima Daiichi nuclear power plant accident, the internal and external exposures of the residents have been very important issues and concerns. Fukushima prefectural government and Fukushima medical university have been performing the Fukushima Health Management Survey, and the external exposures of the residents have been estimated in the survey by using NIRS external dose estimation system. The doses of 66.3% residents were >1 mSv, and 94.8 % were >2 mSv. For estimating internal exposures of the residents, thyroid measurements, whole body counter measurements and simulation have been applied. These three approach estimations showed that the 90 percentile of thyroid equivalent doses were 10-30 mSv for 1-year-old baby and were 10-20 mSv or less for adults. PMID:27664996

  11. Microbial diversities (16S and 18S rRNA gene pyrosequencing) and environmental pathogens within drinking water biofilms grown on the common premise plumbing materials unplasticized polyvinylchloride and copper.

    Science.gov (United States)

    Buse, Helen Y; Lu, Jingrang; Lu, Xinxin; Mou, Xiaozhen; Ashbolt, Nicholas J

    2014-05-01

    Drinking water (DW) biofilm communities influence the survival of opportunistic pathogens, yet knowledge about the microbial composition of DW biofilms developed on common in-premise plumbing material is limited. Utilizing 16S and 18S rRNA gene pyrosequencing, this study characterized the microbial community structure within DW biofilms established on unplasticized polyvinyl chloride (uPVC) and copper (Cu) surfaces and the impact of introducing Legionella pneumophila (Lp) and Acanthamoeba polyphaga. Mature (> 1 year old) biofilms were developed before inoculation with sterilized DW (control, Con), Lp, or Lp and A. polyphaga (LpAp). Comparison of uPVC and Cu biofilms indicated significant differences between bacterial (P = 0.001) and eukaryotic (P 0.05) but did affect eukaryotic members (uPVC, P < 0.01; Cu, P = 0.001). Thus, established DW biofilms host complex communities that may vary based on substratum matrix and maintain consistent bacterial communities despite introduction of Lp, an environmental pathogen.

  12. Reconstruction of Internal and External Exposures of Fukushima Residents.

    Science.gov (United States)

    Akahane, Keiichi

    2016-09-01

    After the Fukushima Daiichi nuclear power plant accident, the internal and external exposures of the residents have been very important issues and concerns. Fukushima prefectural government and Fukushima medical university have been performing the Fukushima Health Management Survey, and the external exposures of the residents have been estimated in the survey by using NIRS external dose estimation system. The doses of 66.3% residents were >1 mSv, and 94.8 % were >2 mSv. For estimating internal exposures of the residents, thyroid measurements, whole body counter measurements and simulation have been applied. These three approach estimations showed that the 90 percentile of thyroid equivalent doses were 10-30 mSv for 1-year-old baby and were 10-20 mSv or less for adults.

  13. Airway management in Escobar syndrome: A formidable challenge

    Directory of Open Access Journals (Sweden)

    Shaji Mathew

    2013-01-01

    Full Text Available Escobar syndrome is a rare autosomal recessive disorder characterized by flexion joint and digit contractures, skin webbing, cleft palate, deformity of spine and cervical spine fusion. Associated difficult airway is mainly due to micrognathia, retrognathia, webbing of neck and limitation of the mouth opening and neck extension. We report a case of a 1 year old child with Escobar syndrome posted for bilateral hamstrings to quadriceps transfer. The child had adequate mouth opening with no evidence of cervical spine fusion, yet we faced difficulty in intubation which was ultimately overcome by securing a proseal laryngeal mask airway (PLMA and then by intubating with an endotracheal tube railroaded over a paediatric fibreoptic bronchoscope passed through the lumen of a PLMA.

  14. Nationwide survey of bovine leukemia virus infection among dairy and beef breeding cattle in Japan from 2009-2011.

    Science.gov (United States)

    Murakami, Kenji; Kobayashi, Sota; Konishi, Misako; Kameyama, Ken-ichiro; Tsutsui, Toshiyuki

    2013-01-01

    A nationwide survey of bovine leukemia virus (BLV) infection was conducted among dairy and beef breeding cattle in Japan from 2009-2011 using an enzyme-linked immunosorbent assay. Of a total of 20,835 cattle tested, 35.2% were seropositive for BLV and the animal type-level seroprevalences in dairy and beef breeding cattle were 40.9 and 28.7%, respectively. By the time animals were 1 year old, 21.0% of dairy and 13.7% of beef breeding cattle were considered infected. Our findings indicate that BLV is widespread among dairy and beef breeding cattle in Japan with the BLV seroprevalences approximately 10- and 4-fold higher, respectively, than previously reported for 1980-1982 in Japan.

  15. Infective endocarditis of the aortic valve in a Border collie dog with patent ductus arteriosus.

    Science.gov (United States)

    Aoki, Takuma; Sunahara, Hiroshi; Sugimoto, Keisuke; Ito, Tetsuro; Kanai, Eiichi; Fujii, Yoko

    2015-03-01

    Infective endocarditis (IE) in dogs with cardiac shunts has not been reported previously. However, we encountered a dog with concurrent patent ductus arteriosus (PDA) and IE. The dog was a 1-year-old, 13.9-kg female Border collie and presented with anorexia, weight loss, pyrexia (40.4 °C) and lameness. A continuous murmur with maximal intensity over the left heart base (Levine 5/6) was detected on auscultation. Echocardiography revealed a PDA and severe aortic stenosis (AS) caused by aortic-valve vegetative lesions. Corynebacterium spp. and Bacillus subtilis were isolated from blood cultures. The dog responded to aggressive antibiotic therapy, and the PDA was subsequently surgically corrected. After a series of treatments, the dog showed long-term improvement in clinical status. PMID:25391395

  16. Dystocia Ystocia Due to Due to Mummifiedummified Foetaloetal Monsteronster in ain a Yankasaankasa Ewewe: A Casease Reporteport

    Directory of Open Access Journals (Sweden)

    A.I. Kisani

    2012-06-01

    Full Text Available A 1 year old Yyankasa ewe weighing 24 kg was presented to the Large Animal Clinic unit of the Veterinary Teaching Hospital, University of Agriculture Makurdi, Nigeria. The owner with the complained t that she has been in labour for 24 h without delivery. Vital parameters were taken and found to be within the normal ranges. the The patient underwent general and obstetrical animal was examinationed. A diagnosis of dystocia was made with Tthe foetus was found to be in anterior presentation of the fetus, bilateral with the carpalus and shoulder flexioned and the neck deviated laterally.lateral deviation of the neck. Manual traction to deliver the foetus was not successful. Caesarean section was performed with the patient under sedation and epidural anaesthesiatherefore recommended. This was carried out and the dead foetus removed. Recovery post surgery was complete and the ewe was discharged five days post surgery.

  17. Mycobacterium fortuitum lipoid pneumonia in a dog.

    Science.gov (United States)

    Leissinger, M K; Garber, J B; Fowlkes, N; Grooters, A M; Royal, A B; Gaunt, S D

    2015-03-01

    A 1-year old female spayed German Shepherd dog was evaluated for acute onset of dyspnea. Pyogranulomatous inflammation and green globoid structures were present on aspirates of the affected lung. Impression smears and histopathology confirmed pyogranulomatous pneumonia, with large amounts of lipid corresponding to the green structures noted cytologically, and identified poorly staining bacterial rods within lipid vacuoles. Special stains confirmed the presence of acid-fast bacterial rods, and polymerase chain reaction and DNA sequencing identified the organism as Mycobacterium fortuitum. M. fortuitum pneumonia is well described in humans and has previously been reported in 4 dogs and 1 cat. Lipid was a prominent cytologic and histologic feature, as is often described in humans and in the single feline case report. Additionally, this case highlights the variable cytologic appearance of lipid, as well as Mycobacterium spp, which are classically nonstaining with Wright-Giemsa. PMID:24788402

  18. Intervention analysis of introduction of rotavirus vaccine on hospital admissions rates due to acute diarrhea

    Directory of Open Access Journals (Sweden)

    Maria de Lourdes Teixeira Masukawa

    2014-10-01

    Full Text Available The aim of this study is to investigate the impact of rotavirus vaccine on hospitalization rates for acute diarrhea in children younger than 5 years old after the introduction of the vaccine in 2006. A descriptive analytical observational study was carried out of the hospitalization rates occurred between 2000 and 2011 in 22 Regional Health Centers of Paraná State, Brazil. The effect of the vaccine was assessed by applying the SARIMA/Box-Jenkins time series methodology of intervention analysis, which allows verifying the slopes of the series are different after the introduction of the vaccine and estimating the magnitude of these effects for children younger than five years of age, by age group, for each region center. It was verified a statistically significant reduction by center/month on hospitalization rates for children 1 year old and younger, with averages of 47% and 58%, respectively, in December 2011.

  19. Is age the limit for human-assisted reproduction techniques? 'Yes', said an Italian judge.

    Science.gov (United States)

    Gulino, Matteo; Pacchiarotti, Arianna; Vergallo, Gianluca Montanari; Frati, Paola

    2013-04-01

    Although use of assisted reproduction techniques was examined by an ad hoc act in 2004 in Italy, there are many opposing views about ethical and economic implications of the technologies dealing with infertility and sterility problems. In this paper, the authors examine a recent judge's decision that ordered the removal and subsequent adoption of a 1-year-old child because her parents were considered too old to be parents. The couple had had recourse to heterologous artificial insemination abroad and decided to give birth in Italy. The judgement deals with and discusses the complex issue of the right to procreate in order to balance the opportunities offered by scientific progress with the unborn child's condition.

  20. Spontaneous tumours in captive African hedgehogs (Atelerix albiventris): a retrospective study.

    Science.gov (United States)

    Raymond, J T; Garner, M M

    2001-01-01

    Forty tumours were diagnosed in 35 (53%) of 66 captive African hedgehogs documented at Northwest ZooPath (NZP) between 1994 and 1999. Three hedgehogs had more than one type of tumour and the remaining 32 had a single type. Of the 35 hedgehogs with tumours, 14 were female, 11 were male, and 10 were of unknown gender; 21 were from zoological parks and 14 were privately owned. Twenty of the hedgehogs with tumours were adult (>1 year old) with a median age of 3.5 years (range 2-5.5 years); 15, of unreported age, were classified as adult. Thirty-four (85%) of the 40 tumours were classified as malignant and six (15%) as benign. The integumentary, haemolymphatic, digestive and endocrine systems were common sites for tumours. The most common tumours were mammary gland adenocarcinoma, lympho-sarcoma and oral squamous cell carcinoma. PMID:11222009

  1. Potenciales evocados auditivos del tallo cerebral en monos rhesus (Macaca mulatta en diferentes etapas fisiológicas en condiciones de cautiverio Brainstem's auditory evoked potentials in rhesus monkeys (Macaca mulatta in different physiologic stages under captivity

    Directory of Open Access Journals (Sweden)

    A Ibáñez-Contreras

    2011-01-01

    Full Text Available La audición juega un papel importante en el desarrollo de conductas más elaboradas en los organismos a medida en que se asciende en la escala filogenética. El objetivo de este estudio fue evaluar la respuesta de la vía auditiva en la especie Macaca mulatta, en diferentes etapas fisiológicas, a través de los Potenciales Evocados Auditivos del Tallo Cerebral (PEATC. Se utilizaron 30 primates no humanos de la especie Macaca mulatta divididos en dos grupos de 15 machos y 15 hembras. Cada grupo estuvo constituido por 3 machos y 3 hembras: Grupo 1 (0,1-3,1 años; Grupo 2 (3,2-6,1 años; Grupo 3 (6,2-9,1 años; Grupo 4 (9,2-12,1 años y Grupo 5 (12,2-27,1 años. Los PEATC se obtuvieron mediante la estimulación de los oídos con “clicks” de rarefacción a 50 dB de intensidad. La actividad eléctrica cerebral fue recogida por medio de electrodos de disco, colocados en las derivaciones Cz (+, A1, A2 (- y Fz como tierra, según el sistema 10/20 internacional. Se observaron cuatro ondas; debido a que no se encontraron diferencias significativas en t de student por aferencias separadas, se realizó ANOVAs con las aferencias unidas. Se observó que los grupos 1 y 5 presentan diferencias significativas en todas las ondas evaluadas, presentando las latencias más alargadas en relación a los demás grupos. Se concluye que a través de los PEATC es posible conocer los cambios que se generan a partir del desarrollo, maduración y envejecimiento de los monos rhesus.In the phylogenetic scale, audition plays a very important role in the development of elaborated behaviors. The aim of this study was to evaluate the auditive response in the Macaca mulatta species at different physiologic stages, through brainstem's auditory evoked potentials (BAEP. 30 non-human primates Macaca mulatta were allotted into two groups of 15 males and 15 females distributed in five age-dependant groups of 2 males and 2 females as follows: Group 1 (0,1-3,1 year old; Group 2 (3,2-6,1

  2. [Surgical Treatment of Large Muscular Ventricular Septal Defect nearby the Moderator Band Using the Sandwich Method;Report of a Case].

    Science.gov (United States)

    Motokawa, Mamika; Sasahara, Akihiro; Terakawa, Katsunari; Miyamoto, Takashi

    2016-09-01

    We describe the rare case of a 1-year-old girl who had large muscular ventricular defect (VSD) nearby the moderator band. We experienced the patch closure using sandwich method. A 1-month-old girl was referred to our institution for treatment of muscular VSD. At the age of 2 month, she underwent the pulmonary artery banding to control the pulmonary high flow. After follow up, the patient have reached 70 cm tall and weighed 7 kg. One year after the "sandwich operation", cardiac catheterization revealed the tiny residual shunt. Nevertheless, the cardiac function was good and the growth was in fine fettle. Sandwich method is a useful surgical technique to close the muscular VSD without resect the right ventricular trabeculation.

  3. Burnei’s disease: teratological spondylolysis

    Science.gov (United States)

    Gavriliu, ST; Ghiță, RA; El Nayef, T; Burnei, A; Olaru-Barbilian, CR

    2015-01-01

    Teratological spondylolysis is a pathological entity noted for the first time in the specialty literature by Gh. Burnei in “The Spine Journal”, in September 25, 2014. This disease was described in a short presentation of the first case treated by the author. The aim of this paper was to expose in a didactic manner the main characteristic aspects of Burnei’s disease: embryological, clinical, imaging and treatment data and also to make known this pathological entity with all its pathognomonic diagnostic elements. This paper was based on data obtained after analyzing 2 cases of teratological spondylolysis: a 18-year-old patient with triple L3-L5 teratological spondylolysis with Pang 1 spinal dysraphism and a 1-year-old child with teratological spondylolysis and retrospondylolisthesis. PMID:26664464

  4. Sudden death in a captive meerkat (Suricata suricatta with arterial medial and myocardial calcification

    Directory of Open Access Journals (Sweden)

    Laura Bongiovann

    2016-04-01

    Full Text Available A 1-year-old male meerkat was found dead by the owner. The animal was clinically healthy and was regularly vaccinated for distemper virus. Necropsy revealed multifocal to confluent dry white areas in the myocardium, pneumonia and congestive hepatopathy. All the other organs, including gross vessels, were macroscopically normal. The heart showed histologically large, multifocal to confluent areas of mineralization of the myocardium and the wall of small coronary artery. Vascular calcifications were also observed in the hepatic portal tracts and kidneys arteries of small/medium sizes. The arterial lumen appeared narrowed and the wall thickened due to the calcification of the tunica media. In veterinary medicine, arterial mineralization is regarded as a metastatic calcification, as the result of hypercalcemia and/or hyperphosphatemia. However, today, the pathogenesis of medial artery calcification in humans seems to be the results of an active process resembling embryonic osteogenesis, rather than a mere passive process.

  5. Leaching of mercury-containing cement monoliths aged for one year.

    Science.gov (United States)

    Svensson, Margareta; Allard, Bert

    2008-01-01

    A directive from the Swedish Government states that waste containing more than 1% of mercury shall be permanently deposited. The stabilization of mercury by conversion to a sparingly soluble compound like the sulphide is crucial to ensure long-term immobilization in a permanent storage. Immobilization by the solidification/stabilization (S/S) method and possible formation of HgS from mercury oxide or elemental mercury by reaction with a sulphur source (S or FeS) is investigated by a modified version of the NEN 7345 Dutch tank-leaching test. The diffusion of mercury during 11 months from 1-year-old mercury containing monoliths of Portland and slag cement is demonstrated. In a geologic repository under conditions representative of deep granitic bedrock (bicarbonate buffered to pH 8.6), a favourable monolith combination is slag cement with addition of the iron sulphide troilite. The apparent diffusion coefficient of mercury is estimated. PMID:17544639

  6. PREVALÊNCIA E CORRELAÇÃO ENTRE OBESIDADE, HIPERTENSÃO ARTERIAL E A PRÁTICA DE ATIVIDADE FÍSICA

    Directory of Open Access Journals (Sweden)

    Natália Turri da Silva

    2011-06-01

    Full Text Available In the recent decades, obesity and overweight, important risk factors for the cardiovascular disease development, had a significant increase being the sedentarism one of the most important causes. Considering it, this study aims at analysing the prevalence of obesity and hypertension in users of CEAFiR, besides correlating BMI with SBP and DBP. For that, weight and height were collected to calculate BMI and BP of 163 subjects (114 women and 49 men whose average age was 53.0 ± 16.1 years old. The results showed that 30.1% were classified as obese and 43.6% as overweight. Regarding to HA, 22,7% were classified in 1, 2 or 3 stages of hypertension and 7.4% as isolated systolic hypertension. Therefore, 73,7% were classified as overweight and 30.1% with hypertension. This result reinforces the importance of preventional programs aiming at orient the population, promoting positive changes in lifestyle.

  7. Breath test measurements in combination with indirect calorimetry for estimation of 13C-leucine oxidation in mink (Mustela vison)

    DEFF Research Database (Denmark)

    Tauson, Anne-Helene; Ali, Abdalla; Kanska, Katarzyna;

    2000-01-01

    Gas exchange measurements by means of indirect calorimetry can be used to calculate quantitative substrate oxidation. The results represents average net oxidation values (substrate disappearance rate), but they cannot describe the dynamics of the oxidation processes. Breath test measurements...... with substrates labelled with 13C provide an attractive tool to describe the dynamics of oxidation processes, and may in combination with indirect calorimetry refine estimation of substrate oxidation. The objective of our investigation was to estimate oxidation of 1-13C labelled leucine in mink in response...... to feeding and fasting. Twelve 1-year-old male mink (Mustela vison) were measured in each five consecutive periods by means of indirect calorimetry and simultaneous breath test. In Periods 1, 3 and 5, each lasting 3 days, the animals were fed ad libitum and Periods 2 and 4 were fasting periods, each of 48 h...

  8. Severe parainfluenza pneumonia in a case of transient hypogammalobulinemia of infancy

    Science.gov (United States)

    Cotugno, Nicola; Manno, Emma Concetta; Stoppa, Francesca; Sinibaldi, Serena; Saffirio, Claudia; D'Argenio, Parizia; Marano, Marco; Nardo, Matteo Di; Palma, Paolo

    2013-01-01

    Human parainfluenza viruses (HPIVs) infection, largely known to cause self-limiting bronchiolitis and pneumonia in immune competent patients, can lead to severe to fatal pulmonary disease in immune disorders, such as primary or acquired-immune deficiencies. We report the case of a 1-year-old child who developed an acute respiratory distress syndrome. Because of a progressive respiratory failure unresponsive to conventional treatment extracorporeal membrane oxygenation (ECMO) was rapidly started. HPIV-3 infection was diagnosed on the rhinopharyngeal fluid and immunological examinations revealed a hypogammaglobulinemia. A combination therapy with ribavirin, intravenous immunoglobulin (IVIG) and steroid under ECMO support was started with considerable improvement. Subsequent analysis and more specific immunological assessment resulted normal confirming the diagnosis of transient hypogammaglobulinemia of infancy (THI). This case highlights the importance of prompt therapy with early ECMO support in combination with ribavirin, IVIG and steroids in patients affected by severe HPIV-3 pneumonia and THI. PMID:23814123

  9. Values for preventing influenza-related morbidity and vaccine adverse events in children

    Directory of Open Access Journals (Sweden)

    Schwartz Benjamin

    2005-03-01

    Full Text Available Abstract Background Influenza vaccination recently has been recommended for children 6–23 months old, but is not currently recommended for routine use in non-high-risk older children. Information on disease impact, costs, benefits, risks, and community preferences could help guide decisions about which age and risk groups should be vaccinated and strategies for improving coverage. The objective of this study was to measure preferences and willingness-to-pay for changes in health-related quality of life associated with uncomplicated influenza and two rarely-occurring vaccination-related adverse events (anaphylaxis and Guillain-Barré syndrome in children. Methods We conducted telephone interviews with adult members selected at random from a large New England HMO (n = 112. Respondents were given descriptions of four health outcomes: uncomplicated influenza in a hypothetical 1-year-old child of their own, uncomplicated influenza in a hypothetical 14-year-old child of their own, anaphylaxis following vaccination, and Guillain-Barré syndrome. "Uncomplicated influenza" did not require a physician's visit or hospitalization. Preferences (values for these health outcomes were measured using time-tradeoff and willingness-to-pay questions. Time-tradeoff questions asked the adult to assume they had a child and to consider how much time from the end of their own life they would be willing to surrender to avoid the health outcome in the child. Results Respondents said they would give a median of zero days of their lives to prevent an episode of uncomplicated influenza in either their (hypothetical 1-year-old or 14-year-old, 30 days to prevent an episode of vaccination-related anaphylaxis, and 3 years to prevent a vaccination-related case of Guillain-Barré syndrome. Median willingness-to-pay to prevent uncomplicated influenza in a 1-year-old was $175, uncomplicated influenza in a 14-year-old was $100, anaphylaxis $400, and Guillain-Barré syndrome $4000

  10. Phonetic description of babbling in Danish toddlers born with and without unilateral cleft lip and palate

    DEFF Research Database (Denmark)

    Willadsen, Elisabeth; Albrechstn, Helle

    2006-01-01

    Objective: To investigate prelinguistic vocalization sequences of 1-year-old children with and without cleft lip and palate. Design: Prospective study. Participants: Thirty-eight children born with unilateral cleft lip and palate and 36 control children born without clefts. The cleft children had...... the lip, soft palate, and posterior part of the hard palate repaired at 4 months of age. The lip was closed ad modum Millard, the nose was corrected according to McComb, and the soft palate was closed with a posteriorly based vomer flap. Methods: Data were obtained from a clinical visit during which...... of occurrence of nasal contoids and a smaller frequency of occurrence of alveolar contoids in the cleft group. Canonical babbling was achieved by most children in both groups, and no significant difference was found between the groups. Conclusions: Early closure of the soft palate seems to have a positive...

  11. Agammaglobulinemia in a Patient with Smith-Lemli-Opitz Syndrome: Case Report

    Directory of Open Access Journals (Sweden)

    H. Halik Akar

    2016-02-01

    Full Text Available Smith-Lemli-Opitz syndrome (SLO is a rare autosomal recessive (AR inherited genetic disorder characterized by multiple congenital anomalies, microcephaly, muscular hypotonia, and severe developmental delay. The deficiency of 7-dehydrocholesterol reductase enzyme leads to this syndrome. Patients with SLO display recurrent respiratory infections due to secondary muscular hypotonia which leads to decreased motility and respiratory effort. In this study, we report a 1-year-old boy with SLO presented with recurrent urinary infections and chronic diarrhea with Klebsiella pneumonia positivity in the rectal swabs. The patient had also markedly decreased immunoglobulin G (IgG between 50-100 g/dl. In follow-up of patient, markedly clinical improvement was observed with intravenous immunoglobulin (IVIG replacement. With this study, we would like to draw attention; recurrent infections may indicate primary immunodeficiencies such as agammaglobulinemia in patients with SLO.

  12. FNIRS-based evaluation of cortical plasticity in children with cerebral palsy undergoing constraint-induced movement therapy

    Science.gov (United States)

    Cao, Jianwei; Khan, Bilal; Hervey, Nathan; Tian, Fenghua; Delgado, Mauricio R.; Clegg, Nancy J.; Smith, Linsley; Roberts, Heather; Tulchin-Francis, Kirsten; Shierk, Angela; Shagman, Laura; MacFarlane, Duncan; Liu, Hanli; Alexandrakis, George

    2015-03-01

    Sensorimotor cortex plasticity induced by constraint-induced movement therapy (CIMT) in six children (10.2 ± 2.1 years old) with hemiplegic cerebral palsy (CP) was assessed by functional near-infrared spectroscopy (fNIRS). The activation laterality index and time-to-peak/duration during a finger tapping task were quantified before, immediately after, and six months after CIMT. Five age-matched healthy children (9.8 ± 1.3 years old) were also imaged at the same time points to provide comparative activation metrics for normal controls. In children with CP the activation time-to-peak/duration for all sensorimotor centers displayed significant normalization immediately after CIMT that persisted six months later. In contrast to this longer term improvement in localized activation response, the laterality index that depended on communication between sensorimotor centers improved immediately after CIMT, but relapsed six months later.

  13. Effects of NaCl Stress on Chlorophyll Fluorescence Parameters in Cinnamomum japonicum var. chenii%NaCl胁迫对普陀樟叶绿素荧光参数的影响

    Institute of Scientific and Technical Information of China (English)

    李影丽; 汪奎宏; 杜国坚; 许利群; 杨华; 肖纪军

    2008-01-01

    [Objective] Study on the changes of chlorophyll fluorescence parameters in Cinnamomum japonicum var. chenii under NaCl stress. [Method] The seedling growth increment, chlorophyll content and chlorophyll fluorescence parameters in leaves of 1-year old Cinnamomum japonicum var. chenii were investigated in field experiment. [Result] Under NaCl stress, seedling growth increment reduced and the chlorophyll content decreased to a stable value; changes of Fv/Fm and Fv/Fo showed identical increasing trend and double peak type. With the aggravation of salt stress, most variations were ob- served in Fo, correlations among chlorophyll fluorescence parameters presented "rise-drop" trend (in the treatment of 7 g/L NaCl). [Condusion] Cinna-momum japonicum var. chenii is endowed with strong salt resistance and wide adaptability.

  14. Prolonged breast feeding, diarrhoeal disease, and survival of children in Guinea-Bissau

    DEFF Research Database (Denmark)

    Mølbak, K; Gottschau, A; Aaby, P;

    1994-01-01

    OBJECTIVE: To analyse the impact of breast feeding on diarrhoeal disease and survival in children above 1 year of age in Guinea-Bissau, west Africa. DESIGN: A community study of an open cohort followed up weekly by interviews over 15 months. Data on feeding practices, anthropometry, and survival...... was higher in weaned children than in partially breast fed children, both in 1 year olds (relative risk 1.41; 95% confidence interval 1.23 to 1.62) and in 2 year olds (1.67; 1.29 to 2.15). The mean duration of an episode of diarrhoea was 5.3 days in breast fed children compared with 6.3 days in weaned...... the weaned ones, the benefit in terms of lower morbidity may be more important for child survival in places with a high morbidity from diarrhoea and with high mortality....

  15. Effect of CO2 enhancement on beech (Fagus sylvatica L. seedling root rot due to Phytophthora plurivora and Phytophthora cactorum

    Directory of Open Access Journals (Sweden)

    Tkaczyk Miłosz

    2014-09-01

    Full Text Available Global climate change is associated with higher concentrations of atmospheric carbon dioxide (CO2. The ongoing changes are likely to have significant, direct or indirect effects on plant diseases caused by many biotic agents such as phytopathogenic fungi. This study results showed that increased CO2 concentration did not stimulate the growth of 1-year-old beech Fagus sylvatica L seedlings but it activated pathogenic Phytophthora species (P. plurivora and P. cactorum which caused significant reduction in the total number of fine roots as well as their length and area. The results of the greenhouse experiment indicated that pathogens once introduced into soil survived in pot soil, became periodically active (in sufficient water conditions and were able to damage beech fine roots. However, the trees mortality was not observed during the first year of experiment. DNA analyses performed on soil and beech tissue proved persistence of introduced Phytophthora isolates.

  16. Decreased body fat, elevated plasma transforming growth factor-β levels, and impaired BMP4-like signaling in biglycan-deficient mice.

    Science.gov (United States)

    Tang, Tao; Thompson, Joel C; Wilson, Patricia G; Nelson, Christina; Williams, Kevin Jon; Tannock, Lisa R

    2013-01-01

    Biglycan (BGN), a small leucine-rich proteoglycan, binds the pro-fibrotic cytokine transforming growth factor β (TGFβ) and inhibits its bioactivity in vitro. Nevertheless, it is controversial whether BGN plays an inhibitory role in vivo. Therefore, the purpose of this study was to evaluate the effect of BGN deficiency on TGFβ activity in vivo by studying 1-year-old Bgn null and wild-type (WT) mice on an Ldlr-null background. Phenotypic and metabolic characterization showed that the Bgn null mice had lower body weight, shorter body length, and shorter femur length (all p kidney histology. Overall, we propose that this unexpected phenotype arises from the effects of BGN deficiency in vivo to elevate TGFβ levels while decreasing bone morphogenetic protein 4-like signaling.

  17. Generation of poikiloderma with neutropenia (PN) induced pluripotent stem cells (iPSCs).

    Science.gov (United States)

    Mills, Jason A; Hudock, Kristin M; Sullivan, Spencer K; Herrera, Pamela; Sullivan, Lisa M; Gadue, Paul; French, Deborah L

    2015-11-01

    Poikiloderma with neutropenia (PN, Clericuzio-type poikiloderma with neutropenia) is a rare autosomal recessive disorder caused by biallelic mutations in the USB1 gene (Alias C16orf57 and MPN1). To date, there have been only 37 reported cases worldwide of this disorder that presents with neutropenia, early onset poikiloderma, respiratory infections, palmo-plantar hyperkeratosis, and skeletal defects. Here we described the generation of human induced pluripotent stem cell lines (PN1 and PN2) from the peripheral blood of a 1-year-old patient using the dox-inducible STEMCCA vector. This patient presented with bacteremia, pneumonia, and neutropenia. Analysis of bone marrow demonstrated normal cellularity with trilineage hematopoiesis and neutropenia.

  18. Delleman Oorthuys syndrome

    Directory of Open Access Journals (Sweden)

    Syed Wajahat A Rizvi

    2015-01-01

    Full Text Available Oculocerebrocutaneous or Delleman syndrome is a rare congenital syndrome characterized by microphthalmia/anophthalmia with or without orbital cysts, focal skin defects, intracranial cysts and skin appendages. We here report a case of 1-year-old male child with periocular skin tags, lid colobomas, and dermal hypoplasia. The patient had delayed developmental milestones and history of tonic-clonic seizures. Magnetic resonance imaging of the head revealed a large arachnoid cyst, aplastic cerebellar vermis and polymicrographic pattern of the cerebral cortex. A complex cyst of spleen was also noted on abdominal ultrasonography. Orbital cysts depending on the size can be excised or left alone. Neuroimaging evaluation of patients with congenital orbital cysts and skin appendages is emphasized for early and appropriate management.

  19. Height, weight and body mass index in early adulthood and risk of schizophrenia

    DEFF Research Database (Denmark)

    Sørensen, Holger Jelling; Mortensen, E L; Reinisch, J M;

    2006-01-01

    status when the cohort members were 1 year old, birth weight, birth length, and maternal pre-pregnancy BMI. RESULTS: Forty-five cases of schizophrenia had a lower young adult mean body weight and BMI than controls. A significant inverse relationship between BMI and risk of later schizophrenia was found....... No significant differences between cases and controls were observed with respect to adult height. CONCLUSION: Independent of several possible confounders, an inverse relationship between young adult BMI and risk of later development of schizophrenia was demonstrated in this all-male sample.......OBJECTIVE: To illuminate the possible associations between height, weight, and body mass index (BMI) during early adulthood and the development of schizophrenia. METHOD: This prospective study is based on an all-male sample of 3210 individuals from the Copenhagen Perinatal Cohort, comprising...

  20. Utilization of maternal and child health facilities by the urban poor of Kuala Lumpur.

    Science.gov (United States)

    Gan, C Y; Yusof, K

    1993-06-01

    A survey conducted to assess the extent which the urban poor in rapidly expanding Kuala Lumpur utilize maternal and child health services available to them. The sample consisted of 1,380 households with children below 6 years and yielded 1,233 children below 6 years of age. 74% of the children had been delivered in government hospitals and 86% of the pregnancies had antenatal care in governmental establishments. 89.2% had BCG immunization before they were 1 year old but 13.3% had not received DPT by that age. Immunization was mainly done in government clinics. The overall immunization coverage for the whole of Kuala Lumpur is expected to be higher than these figures limited to the urban poor. Health planners should increase health facilities in the city to accommodate the expanding population. There is a need to continually campaign for immunization to improve coverage among the urban poor.

  1. Comparative analysis of early and middle outcomes of the arterial switch operation in children with complete transposition of the great arteries with ventricular septal defect and severe pulmonary artery hypertension

    Institute of Scientific and Technical Information of China (English)

    LIU Cheng-hu; SU Jun-wu; LI Zhi-qiang; FAN Xiang-ming; CHEN Yan; HE Yan; LIU Ying-long

    2013-01-01

    Background The best age for the arterial switch operation (ASO) in complete transposition of great arteries with ventricular septal defect is usually considered to be within six months.This is because of severe pulmonary arterial hypertension and pulmonary arterial obstructive pathological changes.There are few reports on ASO surgery in children older than three years old.Methods We studied 41 children,including 24 males and 17 females,from January 2010 to December 2011.They were divided into three groups by operation age; 15 patients were <1 year old,13 were 1-3 years old,and 13 were >3 years old.Associated cardiac abnormalities included patent ductus arteriosus in six cases,atrial septal defect in five cases,and mitral regurgitation in two cases.All the patients had echocardiography before the operation.Seventeen patients underwent a coronary computed tomography examination and five patients underwent right heart catheterization.All ASO surgeries were performed under inhalation anesthesia and hypothermic cardiopulmonary bypass.Results Three operative deaths occurred.Two were in the <1 year old group,who died from severe postoperative low cardiac output.The other was two years old and died of postoperative multiple organ failure.There was no significant difference in postoperative mortality and the recent mid-term survival rate among the three groups.Thirty-eight cases were followed up for an average of 11.2 months,ranging 6-20 months.One seven years old patient died of acute diarrhea and electrolyte disturbance arrhythmia caused by food poisoning.Three patients more than three years old still had residual pulmonary arterial hypertension.Conclusion Children older than three years old can still undergo the ASO procedure,but residual pulmonary hypertension is present.

  2. Influence of nutrient supply on shade-sun acclimation of Picea abies seedlings: effects on foliar morphology, photosynthetic performance and growth.

    Science.gov (United States)

    Grassi, G.; Minotta, G.

    2000-05-01

    Norway spruce seedlings (Picea abies Karst.) were grown in low light for one year, under conditions of adequate and limiting nutrition, then transferred to high light. Three months after transfer we measured photosynthesis, leaf nitrogen concentration, leaf chlorophyll concentration and leaf mass per area (LMA) of current-year and 1-year-old shoots; silhouette area ratio (SAR, the ratio of shoot silhouette area to projected needle area) was also measured in current-year shoots. At the foliage level, the effects of light and nutrient treatments differed markedly. Light availability during foliage expansion primarily affected LMA and SAR (morphological acclimation at the needle and shoot level, respectively). By contrast, nutrient supply in high light affected photosynthetic capacity per unit of leaf tissue (physiological acclimation at the cellular level) but did not affect LMA and SAR. The capacity for shade-sun acclimation in foliage formed before transfer to high light differed greatly from that of foliage formed following the transfer. The morphological inflexibility of mature needles (measured by LMA) limited their shade-sun acclimation potential. In contrast, at high nutrient supply, shoots that developed just after the change in photosynthetic photon flux density largely acclimated, both morphologically and physiologically, to the new light environment. The acclimation response of both current- and 1-year-old shoots was prevented by nutrient limitation. Analysis of growth at the whole-plant level largely confirmed the conclusions drawn at the shoot level. We conclude that nutrient shortage subsequent to the opening of a canopy gap may strongly limit the acclimation response of Norway spruce seedlings. Successful acclimation was largely related to the plant's ability to produce sun foliage and adjust whole-plant biomass allocation rapidly. PMID:12651514

  3. Forest age stands affect soil respiration and litterfall in a Black pine forest managed by a shelterwood system in the Central Spain?

    Science.gov (United States)

    Hedo de Santiago, Javier; Borja, Manuel Esteban Lucas; Candel, David; Viñegla Pérez, Benjamin

    2016-04-01

    This study aims to investigate the effects that stand age and forest structure generates on soil respiration and litterfall quantity. The effect of stand age on these variables was studied in a shelterwood system Spanish Black pine chronosequence in central Iberian Peninsula composed of 0-20, 20-40, 40-60, 60-80, 80-100-year-old. For each stand age, six forest stands with similar characteristics of soil type and site preparation were used. Also, a forest area ranging 80-120 years old and without forest intervention was selected and used as control. We also measured organic matter, C:N ratio, soil moisture and pH in the top 10 mineral soil at each compartment. Soil respiration measurements were carried out in three time points (3, 8 and 12 days). Results showed a clear trend in soil respiration, comparing all the experimental areas. Soil respiration showed the same trend in all stands. It initially showed higher rates, reaching stability in the middle of the measurement process and finally lightly increasing the respiration rate. The older stands had significantly higher soil respiration than the younger stands. Soil organic matter values were also higher in the more mature stands. C:N ratio showed the opposite trend, showing lower values in the less mature stands. More mature stands clearly showed more quantity of litterfall than the younger ones and there was a positive correlation between soil respiration and litterfall. Finally, the multivariate PCA analysis clearly clustered three differenced groups: Control plot; from 100 to 40 years old and from 39 to 1 years old, taking into account both soil respiration and litterfall quantity, also separately. Our results suggest that the control plot has a better soil quality and that extreme forest stand ages (100-80 and 19-1 years old) and the associated forest structure generates differences in soil respiration.

  4. Infant Mortality Risk and Paternity Certainty Are Associated with Postnatal Maternal Behavior toward Adult Male Mountain Gorillas (Gorilla beringei beringei.

    Directory of Open Access Journals (Sweden)

    Stacy Rosenbaum

    Full Text Available Sexually selected infanticide is an important source of infant mortality in many mammalian species. In species with long-term male-female associations, females may benefit from male protection against infanticidal outsiders. We tested whether mountain gorilla (Gorilla beringei beringei mothers in single and multi-male groups monitored by the Dian Fossey Gorilla Fund's Karisoke Research Center actively facilitated interactions between their infants and a potentially protective male. We also evaluated the criteria mothers in multi-male groups used to choose a preferred male social partner. In single male groups, where infanticide risk and paternity certainty are high, females with infants <1 year old spent more time near and affiliated more with males than females without young infants. In multi-male groups, where infanticide rates and paternity certainty are lower, mothers with new infants exhibited few behavioral changes toward males. The sole notable change was that females with young infants proportionally increased their time near males they previously spent little time near when compared to males they had previously preferred, perhaps to encourage paternity uncertainty and deter aggression. Rank was a much better predictor of females' social partner choice than paternity. Older infants (2-3 years in multi-male groups mirrored their mothers' preferences for individual male social partners; 89% spent the most time in close proximity to the male their mother had spent the most time near when they were <1 year old. Observed discrepancies between female behavior in single and multi-male groups likely reflect different levels of postpartum intersexual conflict; in groups where paternity certainty and infanticide risk are both high, male-female interests align and females behave accordingly. This highlights the importance of considering individual and group-level variation when evaluating intersexual conflict across the reproductive cycle.

  5. Ethylene Evolution Changes in Tilted Fraxinus mandshurica Rupr. var. japonica Maxim. Seedlings in Relation to Tension Wood Formation

    Institute of Scientific and Technical Information of China (English)

    Sha Jiang; Ke Xu; Na Zhao; Shu-Xin Zheng; Yan-Ping Ren; Yu-Bao Gao; Song Gu

    2009-01-01

    The effects of ethylene on tension wood formation were studied in 3-year-old Fraxinus mandshurica Rupr. var. japonica Maxim, seedlings in two separate experiments. In experiment 1, ethylene evolution of buds and stems was measured using gas chromatography after 0, 2,4, 7,14, and 21 d of treatment; in experiment 2, both aminoethoxyvinylglycine (AVG) and AgNO3 were applied to the horizontally-placed stems, and the cell numbers on sites of applications were measured after 40 d. Ethylene evolution from buds was found to be much greater in tilted seedlings than in upright ones. The cell numbers of wood fibers in shoots and 1-year-old stems were reduced in treatments with 12.5 x 10-7 μmol/L AVG, 12.5 x 10-8 μmol/L AVG, and 11.8 x 10-8 μmol/L AgNO3; whereas the horizontal and vertical diameters were reduced by treatment of 12.5 x 10-7 μnol/L AVG. Ethylene evolutions of shoots and 1-year-old stems were inhibited greatly in comparison with the control by applying 12.5 x 10-7 μmol/L AVG. The formation of a gelatinous layer of wood fibers was affected by neither AVG nor AgNO3 application. These results suggest that ethylene regulates the quantity of wood production, but does not affect G-layer formation in F. mandshurica Rupr. var. japonica Maxim, seedlings.

  6. To Explore the Clinical Nutritional Iron Deficiency Anemia of Infantile%小儿营养性缺铁性贫血的临床分析

    Institute of Scientific and Technical Information of China (English)

    田秀华

    2015-01-01

    Objective To analyze nutritional iron deficiency anemia of infantile.Methods Selected 90 cases nutritional iron deficiency anemia of infantile with clinical data retrospective summary, analysis the clinical characteristics and related risk factors. Results 61.11% of nutritional iron deifciency anemia children at age 7 months to 1 year old, Rural children more than city children, exclusive breastfeeding not add side dish was susceptible to ischemic anemia.Conclusion 7 months to 1 year old belongs to infantile nutritional iron deifciency anemia intensiifes period, prevention timely, diagnosis, treatment and reduce the incidence of the disease.%目的:分析小儿营养缺铁性贫血情况。方法回顾性总结90例小儿营养缺铁性贫血患者临床资料,分析其临床发病特点和相关危险因素。结果61.11%儿童营养缺铁性贫血年龄为7个月~1岁;农村儿童多于城市儿童;纯母乳喂养未添加辅食儿童易患缺血性贫血。结论7个月~1岁属于小儿营养缺铁性贫血高发期,应该及时预防、诊断、治疗,降低该病发生率。

  7. Human exposure to trace elements through the skin by direct contact with clothing: Risk assessment

    Energy Technology Data Exchange (ETDEWEB)

    Rovira, Joaquim [Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Universitat Rovira i Virgili, Sant Llorenç 21, 43201 Reus, Catalonia (Spain); Environmental Engineering Laboratory, Departament d' Enginyeria Quimica, Universitat Rovira i Virgili, Av. Països Catalans 26, 43007 Tarragona, Catalonia (Spain); Nadal, Martí [Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Universitat Rovira i Virgili, Sant Llorenç 21, 43201 Reus, Catalonia (Spain); Schuhmacher, Marta [Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Universitat Rovira i Virgili, Sant Llorenç 21, 43201 Reus, Catalonia (Spain); Environmental Engineering Laboratory, Departament d' Enginyeria Quimica, Universitat Rovira i Virgili, Av. Països Catalans 26, 43007 Tarragona, Catalonia (Spain); Domingo, José L., E-mail: joseluis.domingo@urv.cat [Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Universitat Rovira i Virgili, Sant Llorenç 21, 43201 Reus, Catalonia (Spain)

    2015-07-15

    Metals in textile products and clothing are used for many purposes, such as metal complex dyes, pigments, mordant, catalyst in synthetic fabrics manufacture, synergists of flame retardants, antimicrobials, or as water repellents and odour-preventive agents. When present in textile materials, heavy metals may mean a potential danger to human health. In the present study, the concentrations of a number of elements (Al, As, B, Ba, Be, Bi, Cd, Co, Cr, Cu, Fe, Hg, Mg, Mn, Mo, Ni, Pb, Sb, Sc, Se, Sm, Sn, Sr, Tl, V, and Zn) were determined in skin-contact clothes. Analysed clothes were made of different materials, colours, and brands. Interestingly, we found high levels of Cr in polyamide dark clothes (605 mg/kg), high Sb concentrations in polyester clothes (141 mg/kg), and great Cu levels in some green cotton fabrics (around 280 mg/kg). Dermal contact exposure and human health risks for adult males, adult females, and for <1-year-old children were assessed. Non-carcinogenic and carcinogenic risks were below safe (HQ<1) and acceptable (<10{sup −6}) limits, respectively, according to international standards. However, for Sb, non-carcinogenic risk was above 10% of the safety limit (HQ>0.1) for dermal contact with clothes. - Highlights: • We determined in skin-contact clothes the concentrations of a number of metals. • Dermal contact exposure and health risks for adults and for 1-year-old children were assessed. • Carcinogenic risks were considered as acceptable (<10{sup −6}). • For non-carcinogenic risks, only Sb exceeded a 10% of the HQ for dermal contact with clothes.

  8. Early social cognition in three cultural contexts.

    Science.gov (United States)

    Callaghan, Tara; Moll, Henrike; Rakoczy, Hannes; Warneken, Felix; Liszkowski, Ulf; Behne, Tanya; Tomasello, Michael

    2011-08-01

    The influence of culture on cognitive development is well established for school age and older children. But almost nothing is known about how different parenting and socialization practices in different cultures affect infants' and young children's earliest emerging cognitive and social-cognitive skills. In the current monograph, we report a series of eight studies in which we systematically assessed the social-cognitive skills of 1- to 3-year-old children in three diverse cultural settings. One group of children was from a Western, middle-class cultural setting in rural Canada and the other two groups were from traditional, small-scale cultural settings in rural Peru and India.In a first group of studies, we assessed 1-year-old children's most basic social-cognitive skills for understanding the intentions and attention of others: imitation, helping, gaze following, and communicative pointing.Children's performance in these tasks was mostly similar across cultural settings. In a second group of studies, we assessed 1-year-old children's skills in participating in interactive episodes of collaboration and joint attention.Again in these studies the general finding was one of cross-cultural similarity. In a final pair of studies, we assessed 2- to 3-year-old children's skills within two symbolic systems (pretense and pictorial). Here we found that the Canadian children who had much more experience with such symbols showed skills at an earlier age.Our overall conclusion is that young children in all cultural settings get sufficient amounts of the right kinds of social experience to develop their most basic social-cognitive skills for interacting with others and participating in culture at around the same age. In contrast, children's acquisition of more culturally specific skills for use in practices involving artifacts and symbols is more dependent on specific learning experiences.

  9. Favorable outcome in non-infant children with MLL-AF4-positive acute lymphoblastic leukemia: a report from the Tokyo Children's Cancer Study Group.

    Science.gov (United States)

    Tomizawa, Daisuke; Kato, Motohiro; Takahashi, Hiroyuki; Fujimura, Junya; Inukai, Takeshi; Fukushima, Takashi; Kiyokawa, Nobutaka; Koh, Katsuyoshi; Manabe, Atsushi; Ohara, Akira

    2015-11-01

    Unlike acute lymphoblastic leukemia (ALL) in infants, MLL gene rearrangement (MLL-r) is rare in ALL children (≥1 year old). The outcome and optimal treatment options for MLL-r ALL remain controversial. Among the 1827 children enrolled in the Tokyo Children's Cancer Study Group ALL studies L95-14, L99-15, L99-1502, L04-16, and L07-1602 (1995-2009), 25 MLL-r ALL patients (1.3 %) were identified. Their median age and leukocyte count at diagnosis was 2 years old (range 1-15 years) and 27,690/μL (range 1800-1,113,000/μL), respectively. All but one patient achieved complete remission (CR) after induction therapy, and 19 underwent allogeneic hematopoietic stem cell transplantation (HSCT) in first CR according to the protocol. The 5-year event-free survival (EFS) and overall survival (OS) rate were 60.0 % [standard error (SE), 9.7 %] and 64.0 % (SE 9.6 %), respectively. Notably, 9/12 cases with MLL-AF4-positive ALL are alive in continuous CR with a 75.0 % (SE 12.5 %) EFS rate. The causes of treatment failure were as follows: one induction failure, five relapses, and five transplant-related deaths. With intensive chemotherapy and allogeneic HSCT, favorable outcome of children (≥1 year old) with MLL-AF4-positive ALL was observed. However, considering the risk of acute and late toxicities associated with HSCT, its indication should be restricted.

  10. 小儿营养性缺铁性贫血的临床分析%To Explore the Clinical Nutritional Iron Deficiency Anemia of Infantile

    Institute of Scientific and Technical Information of China (English)

    田秀华

    2015-01-01

    目的:分析小儿营养缺铁性贫血情况。方法回顾性总结90例小儿营养缺铁性贫血患者临床资料,分析其临床发病特点和相关危险因素。结果61.11%儿童营养缺铁性贫血年龄为7个月~1岁;农村儿童多于城市儿童;纯母乳喂养未添加辅食儿童易患缺血性贫血。结论7个月~1岁属于小儿营养缺铁性贫血高发期,应该及时预防、诊断、治疗,降低该病发生率。%Objective To analyze nutritional iron deficiency anemia of infantile.Methods Selected 90 cases nutritional iron deficiency anemia of infantile with clinical data retrospective summary, analysis the clinical characteristics and related risk factors. Results 61.11% of nutritional iron deifciency anemia children at age 7 months to 1 year old, Rural children more than city children, exclusive breastfeeding not add side dish was susceptible to ischemic anemia.Conclusion 7 months to 1 year old belongs to infantile nutritional iron deifciency anemia intensiifes period, prevention timely, diagnosis, treatment and reduce the incidence of the disease.

  11. Recruitment in a Colorado population of big brown bats: Breeding probabilities, litter size, and first-year survival

    Science.gov (United States)

    O'Shea, T.J.; Ellison, L.E.; Neubaum, D.J.; Neubaum, M.A.; Reynolds, C.A.; Bowen, R.A.

    2010-01-01

    We used markrecapture estimation techniques and radiography to test hypotheses about 3 important aspects of recruitment in big brown bats (Eptesicus fuscus) in Fort Collins, Colorado: adult breeding probabilities, litter size, and 1st-year survival of young. We marked 2,968 females with passive integrated transponder (PIT) tags at multiple sites during 2001-2005 and based our assessments on direct recaptures (breeding probabilities) and passive detection with automated PIT tag readers (1st-year survival). We interpreted our data in relation to hypotheses regarding demographic influences of bat age, roost, and effects of years with unusual environmental conditions: extreme drought (2002) and arrival of a West Nile virus epizootic (2003). Conditional breeding probabilities at 6 roosts sampled in 2002-2005 were estimated as 0.64 (95% confidence interval [95% CI] = 0.530.73) in 1-year-old females, but were consistently high (95% CI = 0.940.96) and did not vary by roost, year, or prior year breeding status in older adults. Mean litter size was 1.11 (95% CI = 1.051.17), based on examination of 112 pregnant females by radiography. Litter size was not higher in older or larger females and was similar to results of other studies in western North America despite wide variation in latitude. First-year survival was estimated as 0.67 (95% CI = 0.610.73) for weaned females at 5 maternity roosts over 5 consecutive years, was lower than adult survival (0.79; 95% CI = 0.770.81), and varied by roost. Based on model selection criteria, strong evidence exists for complex roost and year effects on 1st-year survival. First-year survival was lowest in bats born during the drought year. Juvenile females that did not return to roosts as 1-year-olds had lower body condition indices in late summer of their natal year than those known to survive. ?? 2009 American Society of Mammalogists.

  12. Transfer of chlorine from the environment to agricultural foodstuffs

    International Nuclear Information System (INIS)

    The factors governing chlorine transfer from Phaeozem and Greyzem soils to various important crop species (foodstuff and forage) were determined in natural conditions in the Kiev region of Ukraine. The stable chlorine concentration ratio (CR) values were the lowest in apple (0.5 ± 0.3) and strawberry (2 ± 1), higher in vegetables (5 ± 3), seeds (15 ± 7) and reached a maximum in straw (187 ± 90). The average CR values of 36Cl were estimated for the most important crops using all experimental data on 36Cl and stable chlorine transfer into plants from various soils. It was experimentally shown that boiling potatoes in water leads to an equilibrium between 36Cl specific content in the water and moisture in the cooked potato. The 36Cl processing factor (PF) for boiling various foodstuffs is equal to the ratio of water mass in the cooked foodstuff to the total water mass (in the food and the decoction). 36Cl PF for cereal flour can be estimated as 1. The 36Cl processing factor for dairy products is equal to the ratio of residual water mass in the product to initial water mass in milk. At a 36Cl specific activity in soil of 1 Bq kg-1, the estimated annual dietary 36Cl intake into human organism (adult man) is about 10 kBq. Sixty to seventy percent of the above amount will be taken in via milk and dairy products, 7-16% via meat, 14-16% via bread and bakery items and 8-12% via vegetables. The highest annual 36Cl intake, 10.7 kBq, is predicted for 1-year-old children. The expected effective doses from annual 36Cl intake are higher for younger age groups, increasing from 0.008 mSv in adults to 0.12 mSv in 1-year-old children

  13. The use of intonation for turn anticipation in observed conversations without visual signals as source of information

    Directory of Open Access Journals (Sweden)

    Anne eKeitel

    2015-02-01

    Full Text Available The anticipation of a speaker’s next turn is a key element of successful conversation. This can be achieved using a multitude of cues. In natural conversation, the most important cue for adults to anticipate the end of a turn (and therefore the beginning of the next turn is the semantic and syntactic content. In addition, prosodic cues, such as intonation, or visual signals that occur before a speaker starts speaking (e.g., opening the mouth help to identify the beginning and the end of a speaker’s turn. Early in life, prosodic cues seem to be more important than in adulthood. For example, it was previously shown that 3-year-old children anticipated more turns in observed conversations when intonation was available compared with when not, and this beneficial effect was present neither in younger children nor in adults (Keitel, Prinz, Friederici, von Hofsten, & Daum, 2013. In the present study, we investigated this effect in greater detail. Videos of conversations between puppets with either normal or flattened intonation were presented to children (1-year-olds and 3-year-olds and adults. The use of puppets allowed the control of visual signals: The verbal signals (speech started exactly at the same time as the visual signals (mouth opening. With respect to the children, our findings replicate the results of the previous study: 3-year-olds anticipated more turns with normal intonation than with flattened intonation, whereas 1-year-olds did not show this effect. In contrast to our previous findings, the adults showed the same intonation effect as the 3-year-olds. This suggests that adults’ cue use varies depending on the characteristics of a conversation. Our results further support the notion that the cues used to anticipate conversational turns differ in development.

  14. The Effects of Run-of-River Hydroelectric Power Schemes on Fish Community Composition in Temperate Streams and Rivers.

    Directory of Open Access Journals (Sweden)

    Gary S Bilotta

    Full Text Available The potential environmental impacts of large-scale storage hydroelectric power (HEP schemes have been well-documented in the literature. In Europe, awareness of these potential impacts and limited opportunities for politically-acceptable medium- to large-scale schemes, have caused attention to focus on smaller-scale HEP schemes, particularly run-of-river (ROR schemes, to contribute to meeting renewable energy targets. Run-of-river HEP schemes are often presumed to be less environmentally damaging than large-scale storage HEP schemes. However, there is currently a lack of peer-reviewed studies on their physical and ecological impact. The aim of this article was to investigate the effects of ROR HEP schemes on communities of fish in temperate streams and rivers, using a Before-After, Control-Impact (BACI study design. The study makes use of routine environmental surveillance data collected as part of long-term national and international monitoring programmes at 23 systematically-selected ROR HEP schemes and 23 systematically-selected paired control sites. Six area-normalised metrics of fish community composition were analysed using a linear mixed effects model (number of species, number of fish, number of Atlantic salmon-Salmo salar, number of >1 year old Atlantic salmon, number of brown trout-Salmo trutta, and number of >1 year old brown trout. The analyses showed that there was a statistically significant effect (p<0.05 of ROR HEP construction and operation on the number of species. However, no statistically significant effects were detected on the other five metrics of community composition. The implications of these findings are discussed in this article and recommendations are made for best-practice study design for future fish community impact studies.

  15. Human exposure to trace elements through the skin by direct contact with clothing: Risk assessment

    International Nuclear Information System (INIS)

    Metals in textile products and clothing are used for many purposes, such as metal complex dyes, pigments, mordant, catalyst in synthetic fabrics manufacture, synergists of flame retardants, antimicrobials, or as water repellents and odour-preventive agents. When present in textile materials, heavy metals may mean a potential danger to human health. In the present study, the concentrations of a number of elements (Al, As, B, Ba, Be, Bi, Cd, Co, Cr, Cu, Fe, Hg, Mg, Mn, Mo, Ni, Pb, Sb, Sc, Se, Sm, Sn, Sr, Tl, V, and Zn) were determined in skin-contact clothes. Analysed clothes were made of different materials, colours, and brands. Interestingly, we found high levels of Cr in polyamide dark clothes (605 mg/kg), high Sb concentrations in polyester clothes (141 mg/kg), and great Cu levels in some green cotton fabrics (around 280 mg/kg). Dermal contact exposure and human health risks for adult males, adult females, and for <1-year-old children were assessed. Non-carcinogenic and carcinogenic risks were below safe (HQ<1) and acceptable (<10−6) limits, respectively, according to international standards. However, for Sb, non-carcinogenic risk was above 10% of the safety limit (HQ>0.1) for dermal contact with clothes. - Highlights: • We determined in skin-contact clothes the concentrations of a number of metals. • Dermal contact exposure and health risks for adults and for 1-year-old children were assessed. • Carcinogenic risks were considered as acceptable (<10−6). • For non-carcinogenic risks, only Sb exceeded a 10% of the HQ for dermal contact with clothes

  16. Infant Mortality Risk and Paternity Certainty Are Associated with Postnatal Maternal Behavior toward Adult Male Mountain Gorillas (Gorilla beringei beringei).

    Science.gov (United States)

    Rosenbaum, Stacy; Hirwa, Jean Paul; Silk, Joan B; Vigilant, Linda; Stoinski, Tara S

    2016-01-01

    Sexually selected infanticide is an important source of infant mortality in many mammalian species. In species with long-term male-female associations, females may benefit from male protection against infanticidal outsiders. We tested whether mountain gorilla (Gorilla beringei beringei) mothers in single and multi-male groups monitored by the Dian Fossey Gorilla Fund's Karisoke Research Center actively facilitated interactions between their infants and a potentially protective male. We also evaluated the criteria mothers in multi-male groups used to choose a preferred male social partner. In single male groups, where infanticide risk and paternity certainty are high, females with infants <1 year old spent more time near and affiliated more with males than females without young infants. In multi-male groups, where infanticide rates and paternity certainty are lower, mothers with new infants exhibited few behavioral changes toward males. The sole notable change was that females with young infants proportionally increased their time near males they previously spent little time near when compared to males they had previously preferred, perhaps to encourage paternity uncertainty and deter aggression. Rank was a much better predictor of females' social partner choice than paternity. Older infants (2-3 years) in multi-male groups mirrored their mothers' preferences for individual male social partners; 89% spent the most time in close proximity to the male their mother had spent the most time near when they were <1 year old. Observed discrepancies between female behavior in single and multi-male groups likely reflect different levels of postpartum intersexual conflict; in groups where paternity certainty and infanticide risk are both high, male-female interests align and females behave accordingly. This highlights the importance of considering individual and group-level variation when evaluating intersexual conflict across the reproductive cycle.

  17. The use of intonation for turn anticipation in observed conversations without visual signals as source of information.

    Science.gov (United States)

    Keitel, Anne; Daum, Moritz M

    2015-01-01

    The anticipation of a speaker's next turn is a key element of successful conversation. This can be achieved using a multitude of cues. In natural conversation, the most important cue for adults to anticipate the end of a turn (and therefore the beginning of the next turn) is the semantic and syntactic content. In addition, prosodic cues, such as intonation, or visual signals that occur before a speaker starts speaking (e.g., opening the mouth) help to identify the beginning and the end of a speaker's turn. Early in life, prosodic cues seem to be more important than in adulthood. For example, it was previously shown that 3-year-old children anticipated more turns in observed conversations when intonation was available compared with when not, and this beneficial effect was present neither in younger children nor in adults (Keitel et al., 2013). In the present study, we investigated this effect in greater detail. Videos of conversations between puppets with either normal or flattened intonation were presented to children (1-year-olds and 3-year-olds) and adults. The use of puppets allowed the control of visual signals: the verbal signals (speech) started exactly at the same time as the visual signals (mouth opening). With respect to the children, our findings replicate the results of the previous study: 3-year-olds anticipated more turns with normal intonation than with flattened intonation, whereas 1-year-olds did not show this effect. In contrast to our previous findings, the adults showed the same intonation effect as the 3-year-olds. This suggests that adults' cue use varies depending on the characteristics of a conversation. Our results further support the notion that the cues used to anticipate conversational turns differ in development. PMID:25713548

  18. Kinetics of carnitine palmitoyltransferase I (CPT I) in Chinese sucker (Myxocyprinus asiaticus) change with its development.

    Science.gov (United States)

    Liu, Cai-Xia; Luo, Zhi; Hu, Wei; Tan, Xiao-Ying; Zheng, Jia-Lang; Chen, Qi-Liang; Zhu, Qing-Ling

    2014-02-01

    The present study was conducted to evaluate the ontogeny and kinetic of CPT I in several tissues of the Chinese sucker Myxocyprinus asiaticus. To this end, liver, muscle and intestine tissues were examined at five various developmental stages of Chinese sucker: newly-hatched larvae, 68-day-old, 4-month-old, 1- and 2-year-old Chinese sucker, respectively. The total carnitine (TC) content in the liver increased from birth to 1-year-old Chinese sucker and then declined in the 2-year-old Chinese sucker. From the 68-day-old to the 1-year-old Chinese sucker, both free and total concentrations in muscle increased. Both acyl carnitine (AC) and TC concentrations in intestine were very variable at different stages. The ratio of AC to free carnitine (FC) in liver progressively increased from hatching to 4 months, and declined at the age of 1 year, and then increased by 2 years. In muscle, the highest and lowest ratios of AC/FC were observed at 68-days-old and 4 month-old Chinese sucker. The highest proportion of AC/FC in intestine was also observed at 68-day-old Chinese sucker. All the Chinese sucker larvae at hatching had a high value of the Michaelis constant (K(m)) for carnitine. Maximal velocity (V(max)) in intestine increased with age. V(max) in liver and muscle increased with age except a decrease at 4 months in liver and at 2 years in muscle. The FC concentration in the examined tissues at all developmental stages were less than the respective K(m), indicating that Chinese suckers require supplemental carnitine in their food to ensure that CPT I activity is not constrained by carnitine availability. PMID:24264360

  19. Prevalence of intestinal parasites in breeding kennel dogs in Japan.

    Science.gov (United States)

    Itoh, Naoyuki; Kanai, Kazutaka; Kimura, Yuya; Chikazawa, Seishiro; Hori, Yasutomo; Hoshi, Fumio

    2015-03-01

    The present study is the first to show overall prevalences of intestinal parasites among breeding kennel dogs in Japan. A total of 573 fresh fecal samples were collected from dogs at 12 breeding kennels. Giardia-specific coproantigen was examined by ELISA kit (SNAP(®) Giardia, IDEXX Laboratories, Inc., Maine, USA). Other intestinal parasites were determined microscopically using the formalin-ethyl acetate sedimentation technique. Overall prevalences of two genera of protists, Giardia spp. and Cystoisospora spp., were 25.7 and 1.2 %, respectively. The prevalence of helminthes was recorded as: Toxocara canis 0.2 %, Toxascaris leonina 0.9 %, Ancylostoma caninum 0.2 %, Trichuris vulpis 2.1 %, and Spirometra erinacei 0.4 %. According to age categories, Giardia spp., Cystoisospora spp., and T. leonina in <1-year-old dogs were significantly more prevalent than in ≥ 1-year-old dogs (61.0 vs. 19.8 %, P < 0.0001; 7.3 vs. 0.2 %, P < 0.0001; and 4.9 vs. 0.2 %, P < 0.001; respectively). With respect to fecal condition, the prevalences of T. leonina and T. vulpis were significantly higher in unformed stool dogs than in formed ones (2.4 vs. 0 %, P < 0.01, and 4.3 vs. 0.8 %, P < 0.05, respectively). In all of the breeding kennels except for one kennel, intestinal parasite infections were found at the high prevalent, ranging from 16.0 to 70.0 %. PMID:25627028

  20. ANTICORPOS ANTI-Toxoplasma gondii EM CARRAPATOS NO MUNICÍPIO DE GOIÂNIA: LEVANTAMENTO SOROLÓGICO ANTIBODIES ANTI - Toxoplasma gondii IN GOATS IN THE AREA OF GOIÂNIA: SOROLOGICAL SURVEY

    Directory of Open Access Journals (Sweden)

    Guido Fontgalland Coelho Linhares

    2007-09-01

    Full Text Available

    Foi efetuado estudo sorológico para pesquisa de anticorpos anti-Toxoplasma gondii pelo método de hemaglutinação indireta em 109 (cento e nove amostras de soro de caprinos provenientes de 5 (cinco rebanhos distintos do município de Goiânia. Foi encontrado 30,2% de animais positivos com idade inferior a um ano de idade, e 51,5% em animais com idade superior a um ano de idade. Com relação ao sexo, 46,3% das fêmeas foram positivas, enquanto que os machos 33,3%. E finalmente 43,1% quando foram testados os animais de ambos os sexos, exceto os lactantes. O titulo mínimo considerado foi 1/64.

    Studies on prevalence of anti-Toxoplasma gondii antibodies was carried out by the indirect hemaglutination test in 109 caprine sera samples from five distinct heards in Goiânia, Goiás. It had been shown positivity of 30.2% for animals under 1 year old and 51.5% for animals over 1 year old. Between females 46.3% were positive and males 33.3%. And finally 43.1% among animals of both sexes and any age, except lactents. The sera were tested from the inicial dilutron of 1/64.

  1. Critical tidal level for forestation with hypocotyl of Rhizophora stylosa Griff along the Guangxi coast of China

    Institute of Scientific and Technical Information of China (English)

    Binyuan HE; Tinghe LAI

    2009-01-01

    From August 2004 to August 2005, three replicate experimental platforms were constructed in a section of the tidal flats in Yingluo Bay, Guangxi Province to study the growth and physiological responses of Rhizophora stylosa Griff seedlings to tidal waterlogging stress in a diurnal tidal zone. A total of eight tidal flat elevation (TFE) treatments, i.e., 320, 330, 340, 350, 360,370, 380 and 390 cm above Yellow Sea Datum (YSD),were created on each platform. The results showed that lower TFEs (320-330cm YSD) slightly increased the seedling stem height of 1-year old seedlings, while higher TFEs (> 340 cm YSD) increased the seedling growth significantly. Moderate TFEs (350-370 cm YSD) favored the development of knots. Number of leaves, leaf conservation rate and leaf area per seedling all decreased dramatically with decreasing TFE. Lower TFEs caused large damage to Chl a, but Chl b was less affected. The Chl a/b ratio decreased with decreasing TFE. Prolonged waterlogging induced higher SOD activity in roots, while moderate TFE inhibited the SOD activity in leaves. The POD activity in roots and leaves increased with decreasing TFE. Waterlogging stress decreased the biomass of individual organs and entire seedlings. With increasing waterlogging, the biomass partitioning in 1-year old seedlings increased from leaf to stem. The survival rate decreased sharply from 88.9% to 40.0% as TFE decreased,while more than 80% of the seedlings were able to survive at the TFE level of 370 cm YSD and above. We propose that the local mean sea level should be adopted as the critical tidal level for forestation with hypocotyls of R.stylosa along the Guangxi coast.

  2. Efeito analgésico e anti-inflamatório do extrato aquoso das folhas de trevo-roxo (Scutellaria agrestis A. St.-Hil. ex Benth. - Lamiaceae em roedores

    Directory of Open Access Journals (Sweden)

    A.B. Oliveira

    2014-06-01

    Full Text Available Scutellaria agrestis é utilizada por comunidades ribeirinhas do Amazonas principalmente para o tratamento de otites por via tópica utilizando-se o extrato bruto obtido por maceração. O presente trabalho visou investigar preliminarmente o perfil fitoquímico, a segurança toxicológica e as ações analgésica, anti-inflamatória e antiedematogência do extrato aquoso das folhas de S. agrestis. Foram coletados 80 indivíduos da espécie no horto medicinal da Universidade Nilton Lins, Manaus, Brasil. O perfil fitoquímico foi obtido por meio de prospecção da droga vegetal para heterosídeos cianogênicos, terpenos, compostos fenólicos e alcaloides. A toxicologia foi avaliada pelo teste de toxicidade aguda. As atividades analgésicas/ anti-inflamatórias foram analisadas por meio dos testes de formalina em camundongos e a atividade antiedematogência, pelo teste de edema de pata em ratos. Os metabólitos detectados foram fenóis (taninos hidrolisáveis, cumarinas e várias classes de flavonoides e terpenos (esteroides livres, saponinas. Não foi possível estabelecer DL50, haja visto que o extrato não provocou a morte de nenhum animal durante o teste de toxicidade aguda, provavelmente devido à ausência de heterosídeos cianogênicos na sua composição. Apesar de não provocar morte, considerou-se que o extrato apresenta uma discreta toxicidade, uma vez que foi observada a ocorrência de espasmos na primeira hora de observação dos animais. O extrato apresentou ainda efeito analgésico e anti-inflamatório significativo nas doses de 30, 100 e 300 mg/kg pelo teste da formalina, sendo o resultado na maior dose equivalente ao obtido com a droga padrão (fentanil. No entanto, não observamos efeito antiedematogênico nas doses testadas durante as 5 horas de registro do edema de pata. Os resultados obtidos nesta pesquisa conferem base científica preliminar quanto à segurança e ao efeito analgésico e antiinflamatório da droga vegetal, o

  3. A Mídia e o Processo de Pulverização da Figura do Sujeito Cerebral

    Directory of Open Access Journals (Sweden)

    Gustavo Zambenedetti

    2012-01-01

    Full Text Available La expresión “sujeto cerebral” se refiere a una forma de relación consigo que expresa los modos contemporáneos de subjetivación, los cuales tienen tomado el cerebro como referencia para el sentimiento de identidad, definiendo lo que somos y lo que/como debemos ser. Nuestro objetivo es analizar el modo como la figura del sujeto cerebral es vehiculada en los medios de comunicación. Este análisis se hará a partir de reportajes presentados en dos telediarios brasileños. Entendemos que los reportajes posibilitan la comprensión del modo como el lenguaje científico-académico es agregado en el cotidiano, propiciando una ‘difusión’ y naturalización de la figura del sujeto cerebral. Desde la perspectiva de la ontología del presente, propuesta por Michel Foucault, proponemos cambiar lo que los reportajes vehiculan de la posición de evidencia para la posición de problematización. Al analizar reportajes que vehiculan lo que ocurre en el cerebro como explicación para comportamientos y trastornos mentales, discutimos la ambigüedad del significado de la palabra “explicación”, así como la diferencia entre el cerebro ser entendido como causa de determinado fenómeno o condición de posibilidad para que el ocurra. Desde tres reportajes que vehiculan informaciones sobre diferencias o similitudes entre los cerebros, respectivamente, de homosexuales y heterosexuales, pedófilos y no pedófilos, psicópatas y no psicópatas, discutimos las diferencias entre la delimitación de hechos y la atribución de valores a tales hechos, así como posibles efectos de la confusión entre los dos procesos. Presentamos todavía, una serie de reportajes en los que el cerebro surge como matriz explicativa para fenómenos muy diversos, apuntando el movimiento de generalización y difusión de la figura del sujeto cerebral. Afirmamos un posicionamiento político que no desconsidera el avance de las neurociencias y la importancia del cerebro como uno de

  4. Japan, quality tourist destiny: a learner option for Colima

    Directory of Open Access Journals (Sweden)

    Irma Magaña Carrillo

    2007-11-01

    Full Text Available In this research feature presentation some results are presented as "A Propose Plan to implement a Culture with Quality Control in Tourism Business making Mexico an Attractive site in the Asia-Pacific market and Active within the PATA organism in the XXI Millennium". Which was performed in Japan from 2001 to 2004. This thesis acquires the category of qualitative and emergent and it arouse as a first attempt in reaching the point of a systematic application of the theory of the Model for Total Quality through the Total Control of Quality to the tourist product its basis and service as well as to be delivered with the purpose of giving benefits to the Mexican tourist sector, so that it would provide a gaining position of tourist from Asia, mostly Japanese and in this way it would take advantage Mexico’s participation in PATA.During the search field wok several investigation works were carried out, such as depth interviews to top level management (owner and or proprietor manager level of service area from a ransom selection of some Japanese enterprises. It had the start point in the premise that most of the chosen Japanese business selected for search, are managed with own forms of management to serve the base service and deliver it with quality to reach the external customer satisfaction. In this presentation the analysis result of some interviews are shown. For the planned interviews, this search process used some techniques to get precise information whit sound impact on the research about the following key factors: a customer satisfaction in all their needs, b customer satisfaction in their expectations, c customer loyalty to their supplier.Data collected are qualitative and its informant source was bases on the facts of the way they live the reality of serving the base service or product, which whit its delivery and know-how to their external customer. Techniques application has been carefully revised inside the Japanese cultural context

  5. SPATA17的单核苷酸多态性可能是日本减速分裂阻滞患者的遗传危险因素

    Institute of Scientific and Technical Information of China (English)

    Toshinobu Miyamoto[日本; Akira Tsujimura[日本; Yasushi Miyagawa[日本; Eitetsu Koh[日本; Naoko Sakugawa[日本; Hiroe Miyakawa[日本; Hisashi Sato[日本; Mikio Namiki[日本; Akihiko Okuyama[日本; Kazuo Sengoku[日本

    2009-01-01

    遗传机制已经成为一些男性患者不育的一个病因。近年来,通过人类睾丸组织的基因芯片分析鉴定了10个与人类精子发生相关的新基因。其中一个是精子发生相关17基因(SPATA17)。为了研究是否SPATA17基因缺陷与减数分裂导致的无精症有关,我们进行了突变分析,将18个日本减数分裂导致的无精症患者的SPATA17编码区域进行了测序,以及统计分析,其中包括18个减数分裂阻滞患者,20个唯支持细胞综合征(SCOS)患者和96个健康对照男性。没有SPATA17发生突变。但是,减数分裂阻滞患者组检测到了3个单核苷酸多态性(cSNPs:SNPI—SNP3)。减数分裂阻滞患者与其他患者的SNP1和SNP2基因型与等位基因频率无明显不同。但是,SNP3的等位基因频率在减数分裂阻滞患者组中明显升高(P〈0.05)。这项研究表明,sPATA17在人类精子发生,尤其是减数分裂中可能起关键性作用。

  6. O papel do esteroide anabolizante sobre a hipertrofia e força muscular em treinamentos de resistência aeróbia e de força

    Directory of Open Access Journals (Sweden)

    Everton Crivoi do Carmo

    2011-06-01

    Full Text Available INTRODUÇÃO: Os efeitos dos esteroides anabolizantes (EA sobre a massa muscular e força são controversos e dependentes do treinamento realizado e das fibras musculares recrutadas. Com isso, o objetivo deste estudo foi avaliar os efeitos da associação de EA ao treinamento de força ou aeróbio sobre a hipertrofia e força muscular. MÉTODOS: Ratos Wistar (42 foram divididos em seis grupos: sedentário (SC, n = 7, sedentário anabolizante (SA, n = 7, treinado natação controle (TNC, n = 7, treinado natação anabolizante (TNA, n = 7, treinado força controle (TFC, n = 7 e treinado força anabolizante (TFA, n = 7. O EA foi administrado duas vezes por semana (10mg/kg/semana. Os protocolos de treinamento foram realizados durante 10 semanas, cinco sessões semanais. Foram avaliadas a hipertrofia dos músculos sóleo, plantar e gastrocnêmio (massa muscular corrigida pelo comprimento da tíbia, a proteína total muscular (Bradford e a força muscular em patas traseiras (testes de resistência à inclinação. RESULTADOS: Não foram observadas diferenças significantes na hipertrofia do músculo sóleo. Os grupos TFC e TFA apresentaram, respectivamente, hipertrofia de 18% e 31% no músculo plantar comparado ao grupo SC. A hipertrofia foi 13% maior no grupo TFA em relação ao grupo TFC. Resultados semelhantes foram encontrados no músculo gastrocnêmio. Os grupos TFC e TFA apresentaram significantes aumentos na quantidade total de proteína nos músculos plantares, sendo essa mais pronunciada no grupo TFA e positivamente correlaciona a hipertrofia muscular. Observamos aumento de força nas patas traseiras nos grupos TCF e TAF. CONCLUSÃO: A administração de EA ou sua associação ao treinamento aeróbio não aumenta a massa muscular e força. Porém, à associação ao treinamento de força leva a maior hipertrofia muscular em fibras glicolíticas. Portanto, o tipo de treinamento físico, recrutamento muscular e características das fibras

  7. Efeito do gel da babosa (Aloe barbadensis Mill. associado ao ultrassom em processo inflamatório agudo Effect of aloe (Aloe barbadensis Mill. gel combined with ultrasound in the acute inflammatory process

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    A.L.M Maia-Filho

    2011-01-01

    Full Text Available O presente trabalho teve por objetivo analisar a ação antiinflamatória do gel da Babosa a 2% (Aloe barbadensis Mill. associado ao Ultrassom pulsátil no modelo de edema de pata. Foram utilizados 25 ratos Wistar, (200-250 g, divididos em 5 grupos de 5 animais cada. Grupo1 (controle: ratos tratados com solução salina a 0,9%; Grupo 2: ratos tratados topicamente com gel de A. barbadensis Mill. a 2%; Grupo 3: animais tratados com Ultrassom; Grupo 4: ratos tratados com gel de A. barbadensis Mill. a 2% associado ao Ultrassom; Grupo 5 (controle positivo: ratos tratados com Indometacina na dose de 5 mg Kg-1. Os animais dos grupos 1 e 5 receberam os respectivos tratamentos por via intra-peritoneal 30 minutos antes da injeção intra-plantar de carragenina e os grupos 2, 3 e 4 foram tratados por aplicação tópica de gel de A. barbadensis Mill. a 2%, Ultrassom pulsátil e gel de A. barbadensis Mill. associado ao Ultrassom respectivamente 15 minutos após a indução do edema. Os animais do grupo 04 demonstraram redução significativa do edema quando comparados ao grupo controle, ao mesmo tempo, que se mostrou comparável à indometacina. Observou-se que o gel de aloe associado à fonoforose é capaz reduzir a formação do edema de pata em ratosThis work aimed to evaluate the anti-inflammatory action of 2% aloe (Aloe barbadensis Mill. gel combined with pulsed ultrasound in the paw edema model. Twenty-five Wistar rats (200-250 g were divided into 5 groups of 5 animals each. Group1 (control: rats treated with 0.9% saline; Group 2: rats topically treated with 2% aloe gel; Group 3: rats treated with ultrasound; Group 4: rats treated with 2% aloe gel combined with ultrasound; Group 5 (positive control: rats treated with indomethacin at 5 mg Kg-1. Animals of groups 1 and 5 were intraperitoneally treated 30 min before intraplantar carrageenan injection and groups 2, 3 and 4 were treated by topical application of 2% aloe gel, pulsed ultrasound and aloe gel

  8. O efeito do plasma rico em plaquetas no reparo de lesões musculares em ratos

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    Marcelo Luiz Quarteiro

    2015-10-01

    Full Text Available resumo Objetivo: A necessidade de opções terapêuticas para lesões musculares, cada vez mais fre quentes entre os esportistas, fundamentou este estudo experimental, cujo objetivo foi avaliar os efeitos histológicos do plasma rico em plaquetas (PRP no reparo do tecido mus cular de ratos. Métodos: O PRP foi obtido por dupla centrifugação do sangue de cinco animais. Em 30 ratos, foi produzido um trauma no terço médio do ventre do músculo gastrocnêmio de cada mem bro traseiro. Essas lesões não receberam tratamento em seis ratos (12 patas. Em 24 ratos, injeções intralesionais de soro fisiológico a 0,9% e de PRP foram aplicadas nas patas esquer das e direitas, respectivamente. Amostras do tecido tratado e não tratado foram avaliadas histologicamente sete e 21 dias após os procedimentos. Resultados: A quantidade de colágeno nas lesões tratadas com PRP foi significativamente menor do que a das demais lesões na avaliação feita sete dias após o procedimento, mas se equiparou à dos demais grupos na avaliação feita no 21° dia. Houve aumento significativo (p < 0,001 na quantidade de colágeno do sétimo para o 21° dia nas lesões tratadas com PRP, o que não ocorreu nas lesões tratadas de outra forma. O processo inflamatório se mostrou mais intenso nas lesões tratadas com PRP em comparação com as lesões dos outros grupos de tratamento na avaliação feita sete dias após o procedimento; todavia, os aspectos mor fológicos dessas lesões se mostraram similares ao das lesões não tratadas 21 dias após o procedimento. Conclusão: OPRP promoveu completa restituição tecidual entre o sétimo e o 21° dia em lesões musculares experimentais.

  9. Efeitos de um minuto e dez minutos de deambulação em ratos com artrite induzida por adjuvante completo de Freund sobre os sintomas de dor e edema

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    Raquel Pinheiro Gomes

    2014-04-01

    Full Text Available Este estudo avaliou o efeito de dois protocolos de exercício na nocicepção, edema e migração celular em ratos com artrite induzida por CFA. Ratos Wistar fêmeas (200 - 250 g, n = 50 foram induzidos à monoartrite por adjuvante completo de Freund (CFA, Mycobacterium butyricum; 0,5 mg/mL; 50 μL na articulação do joelho direito (TF; n = 24 ou tornozelo direito (TT; n = 26. A incapacitação articular foi mensurada pelo tempo de elevação da pata (TEP; s em 1 minuto de avaliação. O edema do joelho ou tornozelo foi avaliado pela medida do diâmetro articular (AD, cm e pelo edema de pata (EP, mL, respectivamente. Ambos foram avaliados durante 10 dias consecutivos. Dois protocolos de exercício foram realizados: (a exercício constante (TF, n = 6; TT, n = 6, realizando 1 minuto diário de exercício no cilindro (3 r.p.m.; (b exercício variável (TF, n = 6; TT, n = 7, exercício com aumento de 1 minuto por dia, totalizando 10 minutos no último dia. Os grupos-controle (TF, n = 12; TT, n = 13 não realizaram exercício. Após 10 dias, os animais foram eutanasiados para contagem total (células/mm3 e diferencial (mononucleares e polimorfos nucleares; células/mm3 de leucócitos do tecido inflamado. O exercício variável inibiu a incapacitação e o edema em ambas as articulações. Entretanto, reduziu a migração total de leucócitos apenas na articulação TF. O exercício constante inibiu o edema nas duas articulações e reduziu a migração total de leucócitos da articulação TT. Porém, não reduziu a incapacitação. O exercício variável pareceu ser mais efetivo em reduzir os parâmetros inflamatórios em comparação com o exercício constante.

  10. Validação de metodologia espectrofotométrica para quantificação dos flavonóides de Bauhinia cheilantha (Bongard Steudel Validation of spectrophotometric methodology for quantify flavonoid content in Bauhinia cheilantha (Bongard Steudel

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    Tadeu José da Silva Peixoto Sobrinho

    2008-12-01

    Full Text Available Os laboratórios de fitoterápicos necessitam de metodologias que assegurem o controle de qualidade de seus produtos quando os mesmos não constam em farmacopéias ou monografias oficiais. Baseando-se neste fato, o presente estudo visou validar uma metodologia analítica para quantificação de flavonóides contidos nos extratos da pata-de-vaca (Bauhinia cheilantha [Bongard] Steudel, através de espectrofotometria no visível, como equivalentes de Rutina (µg/mL. Todos os parâmetros exigidos pela ANVISA foram avaliados. No teste de especificidade, observou-se a existência de pico máximo a 420 nm. O método foi considerado linear e com alta sensibilidade de quantificação (2,51 µg/mL. O método também mostrou-se robusto e com elevada recuperação (98,36%. Os resultados obtidos para repetibilidade (intra-corrida, precisão intermediária (inter-corridas e reprodutibilidade certificaram a precisão do método com valores entre 0,31 e 3,58%, sendo também considerado exato (95,71-105,50%. Com este estudo, o método proposto foi considerado específico, preciso, reprodutível, exato, de baixo custo e fácil execução.Phytotherapeutic laboratories require access to methodologies that guarantee quality control for their products when these items are not already registered in pharmacopeias or official monographs. As such, the present study sought to validate analytical methodologies for quantifying natural flavonoids contained in extracts of "pata-de-vaca" (Bauhinia cheilantha [Bong.] Steudel using visible light spectrophotometry and a rutin standard (µg/ml. All of the parameters required by ANVISA were evaluated. The specificity test revealed a maximum absorption peak at 420 nm. The methodology was considered linear and of high quantification sensitivity (2.51 µg/ml. The methodology also proved to be robust, and had high recovery levels (98.36%. The results obtained for repeatability, intermediate precision (intra- and inter-day, and

  11. A síndrome anserina Anserine syndrome

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    Milton Helfenstein Jr

    2010-06-01

    Full Text Available Dor no joelho é uma condição comum na clínica diária e a patologia anserina, também conhecida como pata de ganso, tem sido considerada uma das principais causas. O diagnóstico tem sido realizado de maneira eminentemente clínica, o que tem gerado equívocos. Os pacientes queixam-se tipicamente de dor na parte medial do joelho, com sensibilidade na porção ínferomedial. Estudos de imagem têm sido realizados para esclarecer se tais pacientes possuem bursite, tendinite ou ambos os distúrbios na região conhecida como pata de ganso. Entretanto, o defeito estrutural responsável pelos sintomas permanece desconhecido, motivo pelo qual preferimos intitular como "Síndrome Anserina". O diabetes mellitus é um fator predisponente bem reconhecido. O sobrepeso e a osteoartrite de joelho parecem ser fatores adicionais de risco, contudo, seus papéis na gênese da moléstia ainda não são bem entendidos. O tratamento atual inclui anti-inflamatório, fisioterapia e infiltração de corticoide, com evolução muito variável, que oscila entre 10 dias e 36 meses. A falta de conhecimento sobre a etiofisiopatologia e dados epidemiológicos exige futuros estudos para esse frequente e intrigante distúrbio.Knee pain is a common complaint in clinical practice, and pes anserinus tendino-bursitis syndrome (PATB has been frequently diagnosed based only on clinical features that may cause equivocal interpretations. Patients complain of characteristic spontaneous medial knee pain with tenderness in the inferomedial aspect of the joint. Studies with different imaging modalities have been undertaken during the last years to identify whether these patients suffer from bursitis, tendinitis, or both. Nevertheless, little is known regarding the structural defect responsible for this disturbance. Due to these problems and some controversies, we suggest the term "anserine syndrome" for this condition. Diabetes Mellitus is a known predisposing factor for this syndrome

  12. Interacciones de pesquerías ribereñas en Bahía Magdalena-Almejas, Baja California Sur

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    Miguel A. Ojeda Ruiz de la Peña

    2012-01-01

    Full Text Available Con el fin de aportar al desarrollo de un modelo conceptual sobre la pesca ribereña o artesanal en el área de Bahía Magdalena-Almejas, Baja California Sur, se jerarquizó la importancia de 14 pesquerías de la región. La calificación se basó en un análisis cualitativo por puntos y en la estimación de un índice de importancia relativa, con indicadores como los promedios de captura, valor y frecuencia de registro de especies objetivo en desembarcos de embarcaciones menores, de 1998 a 2009; entre ellas están: almeja catarina, escama, camarón, callo de hacha, tiburón, jaiba, calamar, almeja pata de mula, rayas, lisa, pulpo, abulón, langosta y caracol chino. La interacción temporal entre varias de ellas es controlada por vedas oficiales, pero cuando ocurre se reconocen posibles efectos por pesca incidental e ilegal y modificaciones al ecosistema.

  13. A new genus and species of the family Lethaxonidae (Acari, Parasitengona, Hydrachnidia from the island of Coiba (Panama

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    Valdecasas, A. G.

    2010-06-01

    Full Text Available Transitia carlosi n. gen. n. sp. of the family Lethaxonidae is described from the interstitial environment of a small stream in Central America. Following a morphological revision of the adult variation in the family, Transitia n. gen. is proposed, characterized by a posteriorly tapering body shape, three pairs of acetabula arranged linearly, median position of male gonopore in relation to first pair of genital acetabula and slight sexual dimorphism of male legs.

    Se describe Transitia carlosi n. gen. n. sp. de la familia Lethaxonidae del medio intersticial de un pequeño río en America Central. Tras la revisión morfológica de la variación en los adultos de la familia se propone Transitia n. gen., caracterizado por una forma del cuerpo estrechada posteriormente, tres pares de acetábulas dispuestos linealmente, posición media del gonóporo del macho en relación a los acetábulas genitales y ligero dimorfismo sexual de las patas del macho.

  14. Mayas de Yucatán, México

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    Judith Ortega Canto

    2006-01-01

    Full Text Available El artículo describe y analiza el proceso de transformación de las representaciones sociales respecto a la salud/enfermedad/atención de procesos de embarazo-partopuerperio, a través de tres generaciones de parejas y la condición de género. Es a partir del papel que juega la ideología biomédica representada en las clínicas de campo de la seguridad social, y las relaciones que operan entre hombres y mujeres, que es posible distinguir los elementos protectivos y curativos, así como los elementos de tensión existentes. El trabajo muestra cómo juegan los géneros a través de tres generaciones en términos de colaboración mutua, su demanda y evaluación a la atención recibida por las parteras o a los servicios de atención alópatas, y el efecto de la medicalización sobre hombres y mujeres de la tercera generación.

  15. Autoconsumo de hierbas medicinales en usuarios con enfermedades cardio-vasculares en una comuna de Chile

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    Lizet Veliz-Rojas

    2015-09-01

    Full Text Available Objetivo: Caracterizar el autoconsumo de hierbas medicinales en usuarios con enfermedades cardiovasculares. Metodología: Estudio de tipo cuantitativo y transversal, con una muestra de 257 personas. Los instrumentos recolectores de datos fueron un cuestionario y la revisión de la ficha clínica. Se utilizó un análisis descriptivo univariante apoyado en SPSS. Resultados: El 80,80% de los encuestados usó hierbas medicinales, y el 72,76% señaló no informar esta práctica al equipo de salud. Las hierbas medicinales más utilizadas para el control de la enfermedad cardiovascular fueron: el limón (20,6% para bajar la presión arterial, la pata de vaca (7% para reducir la glicemia y la alcachofa (3,5% para controlar el colesterol. Conclusiones: La mayoría de los participantes recurrieron a las hierbas medicinales, pese a ser una práctica de autocuidado prevalente, no es informada al equipo de salud. Algunas hierbas utilizadas por la muestra para controlar la enfermedad cardiovascular, están descritas sus usos para otras causas. Esta situación podría reflejar el desconocimiento sobre su utilización. Se sugiere el desarrollo de estrategias para el adecuado uso de las hierbas medicinales en atención primaria, enfocado en la integralidad en salud.

  16. Primer registro de Elachistocleis skotogaster Lavilla, Vaira & Ferrari, 2003 (Anura: Microhylidae para la provincia de Formosa, Argentina

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    Kehr, Arturo Ignacio

    2011-10-01

    Full Text Available Entre el 4 de marzo y el 25 de abril de 2011, en 6 sistemas de trampas instalados en la Provinciade Formosa, Ciudad de Las Lomitas, Departamento Patiño, Ruta Nacional N° 81, Establecimiento Sumayen 2000 (24°39'49,4" S; 60°38'29,9" O; 137 m.s.n.m.; datum WGS84, fueron colectados 32 microhílidos con vientre gris manchado de blanco, y características franjas y manchas de color naranja endiferentes partes de las patas, axilas e ingle. Dichos ejemplares, correspondientes al género Elachistocleis se encuentran depositados en la colección herpetológica del Laboratorio de Herpetología del Centro de Ecología Aplicada del Litoral. Luego de analizar los ejemplares colectados (fijados y preservados en formol al 10% consideramos que se trata de E. skotogaster por presentarlas siguientes características morfológicas externas especificadas por Lavilla et al. (2003.

  17. A new species of Caenis (Ephemeroptera: Caenidae from Colombia Una nueva especie de Caenis (Ephemeroptera: Caenidae de Colombia

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    Carlos Molineri

    2009-12-01

    Full Text Available The new species Caenis tarapoto is described from male imagos collected in the Amazonas region from Colombia. This new species is characterized by a dark brown general coloration, presternal triangle anteriorly pointed, forelegs 0.7-0.9 times length of body, forceps apically pointed, central sclerite of styliger plate elongated, penes with gently convex posterior margin and with lobes of penes completely fused and projected laterally.La nueva especie Caenis tarapoto es descripta a partir de imagos machos colectados en la región Amazónica de Colombia. Esta nueva especie se caracteriza por una coloración general castaña oscura, triángulo prosternal aguzado anteriormente, patas anteriores 0.7-0.9 veces la longitud del cuerpo, forceps aguzados en el ápice, esclerito central de la placa estilígera elongado, penes con margen posterior suavemente convexo y con lóbulos peneanos completamente fusionados y proyectados lateralmente.

  18. Carbohydrate composition of serum low and high density lipoproteins of nonhuman primate species.

    Science.gov (United States)

    Pargaonkar, P S; Radhakrishnamurthy, B; Srinivasan, S R; Berenson, G S

    1977-01-01

    1. Carbohydrate composition of serum low and high density lipoproteins obtained from 5 nonhuman primate species (chimpanzee, patas, baboon, rhesus, and spider) and humans was studied. 2. Individual lipoproteins were isolated from pooled sera of each species by ultracentrifugal flotation between the densities 1.019-1.063 for LDL-2; 1.063-1.12 for HDL-2; and 1.12-1.21 for HDL-3. After delipidation, sialic acid, fucose, glucosamine, mannose, galactose, and glucose were determined on apo LDL-2, apo HDL-2, and apo HDL-3. 3. Glucosamine, galactose, and mannose constituted a major component of the sugars in apo LDL-2, with similar relative proportions in all species. Sialic acid, fucose, and glucose formed a minor component, the proportions of which varied greatly among the species. 4. Unlike apo LDL-2, sialic acid, fucose, and glucosamine constituted the bulk of the sugars in apo HDL-2 and apo HDL-3. Mannose, galactose, and glucose were minor components, with galactose predominating. 5. Qualitative differences were observed in electrophoretic mobilities of apo HDL-2 and apo HDL-3 on polyacrylamide gel. One faster moving band was unique to chimpanzee. 6. Intraspecies differences in the content of sialic acid and fucose of apolipoproteins may be related to lipoprotein metabolism and species susceptibility (or resistance) to either spontaneous or diet-induced atherosclerosis. PMID:233783

  19. Conductas agresivas en la escuela, organización psicológica y vínculación parental

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    María Eugenia Villalobos Valencia

    2013-01-01

    Full Text Available Este estudio explora la representación de la relación con las figuras parentales que tienen niños escolarizados con conductas agresivas frecuentes y repetitivas. Se aborda desde una perspectiva clínica uti- lizando como instrumentos de evaluación la entrevista clínica y dos pruebas proyectivas: test del dibujo de la familia y test de Pata Negra. Se encontró que las conductas agresivas hacia los otros pueden ser manifestaciones de una organización psicológica que vivencia al otro como una amenaza a su integridad; el sentimiento continuo de peligro hace que los individuos mal interpreten las situaciones frenando las posibilidades de desarrollo de las habilidades sociales y del reconoci- miento propio de su ser. No hay en ellos una constitución identitaria de sí que les permita referenciarse para situar los eventos, tomar distancia de ellos y buscar recursos representacionales con los que podrían enfrentar comprensivamente lo que les sucede.

  20. Efecto de la edad, el sexo y el tiempo en la biometría del Piquituerto común (Loxia curvirostra curvirostra en Navarra = Effect of age, sex and time in the biometrics of common crossbill (Loxia curvirostra curvirostra in Navarre.

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    D. Alonso, J. Arizaga

    2005-01-01

    Full Text Available Se estudia en detalle la biometría del Piquituerto Común (Loxia curvirostra curvirostra en Navarra (N de España, W de Pirineos, según los sexos, edad y el año de captura. entre 1994 y 2006 se capturaron un total de 2101 aves, en dos localidades emplazadas en bosques de pino silvestre (Pinus sylvestris. Además de la edad y sexo, en cada ejemplar se tomaron diez medidas, relacionadas con el ala, cola, pata y pico, y la morfología del ala de 2004 a 2006. Para toda variable hubo diferencias significativas entre los sexos y edades, presentando los valores máximos los machos adultos, y los mínimos las hembras jóvenes. Tras eliminar el efecto de la edad y sexo, se observaron diferencias interanuales, posiblemente debido a la ocurrencia de aves irruptivas. en lo relativo a la morfología alar, la especie parece mostrar en promedio alas apuntadas y cóncavas, sugiriendo cierta naturaleza nómada, tal vez debido a la variabilidad en la producción de semillas en el pino silvestre. Además, se registraron diferencias entre los sexos, mostrando los machos un ala más apuntada y convexa. Se desconocen por ahora las causas de esta variabilidad.

  1. STUDI PERKEMBANGAN STRUK TUR KOMUNITAS IKAN KARANG DI TERUMBU BUATAN BERBENTUK HEXADOME PADA BERBAGAI KONDISI PERAIRAN DI KABUPATEN BULELENG, BALI

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    YUNALDI YUNALDI

    2015-06-01

    Full Text Available Artificial reefs are made to act as temporary substitutes for small areas of damaged original reef. The structures attract fish and other marine organisms, which can eventually be exploited (e.g. for human food, so it is expected that they will form the basis around which natural reefs can grow and recover. The purpose of this study is to document recruitment of organisms onto the artificial structures, evaluate the effectiveness of the structures in terms of shape and recruitment potential, and use the recruitment information to show which species occur in the surrounding reefs. This research was conducted from May-July 2010 in north Bali, in the Village District Gerokgak Patas, Kampung Baru Village in Buleleng District, and Penuktukan Village, Kecematan Tejakula. The research method used was a visual census method to determine the number of fish species and fish abundance on artificial reefs at three different locations. Three replications were performed at each location. 2481 individuals from 18 families (38 species of reef fish were observed. The area with the greatest abundance of fish and the highest number of fish species was in Kampung Baru, with 1170 individuals from 21 species of fish. Dominant reef fish species were Plotosus lineatus (Cat Fish - 510 individuals, Pomacentrus auriventris (Goldbelly damsel- 256 individuals, Dascyllus trimaculatus (Three spot damsel - 335 individuals, Pseudanthias squamipinnis (Lyretail Anthias - 320 individuals. A Sorensen analysis showed that reef fish communities on the artificial reefs in the form of 'hexadomes' were not derived from the surrounding reefs.

  2. Un letto funebre con decorazione in osso da Teramo (Italia

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    d'Agata, Maria Grazia

    1997-12-01

    Full Text Available The authors propose a morphological and iconographic reconstruction of a Roman funeral couch decorated in bone working upon numerous cladding pieces coming from a grave in bustum in the necropolis of La Cona – Teramo (Abruzzo. The bed, classified within the «turned legs» typology, was probably adorned with a Bacchic iconographic theme and can be dated on the first half of the 1st century A.D., the time that records the widest diffusion of this kind furniture.Las autoras proponen la reconstrucción morfológica e iconográfica de la decoración en hueso de un lecho funerario romano a partir de numerosos fragmentos de revestimiento procedentes de una sepultura in bustum de la necrópolis de La Cona en Teramo (Abruzzo. El lecho, integrado en la tipología del mobiliario con "patas torneadas", estaba probablemente adornado con un tema báquico y se encuadra cronológicamente en la primera mitad del siglo I d.C, época de mayor difusión de este tipo de muebles.

  3. Atividade antiinflamatória do granulado de Calendula officinalis L. e Matricaria recutita L.

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    L.R. Sartori

    2003-01-01

    Full Text Available Este trabalho descreve os resultados da atividade antiinflamatória de um granulado composto pelos extratos secos de Calendula officinalis L. e Matricaria recutita L. (GECOMR® - granulado encapsulado de Calendula officinalis e Matricaria recutita. Estas espécies são utilizadas na medicina popular devido às suas atividades antiinflamatória, antiúlcera gástrica e antiespasmódica. A redução do processo edematogênico nos grupos de animais tratados com o GECOMR foi observada para todos agentes inflamatórios testados (Carragenina, dextrana e histamina. Esta associação mostrou-se eficaz sobre os modelos de edema de pata induzidos pelas diferentes substâncias inflamatórias, com as doses de 100 e 250 mg.kg-1. A associação dos extratos hidroalcoólicos destas espécies medicinais não modificou a indicação isolada de cada uma.

  4. The Patient’s Experience of the Psychosocial Process That Influences Identity following Stroke Rehabilitation: A Metaethnography

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    E. Hole

    2014-01-01

    Full Text Available Background and Purpose. Patient experience is increasingly being recognised as a key health outcome due to its positive correlation with quality of life and treatment compliance. The aim of this study was to create a model of how patient’s experiences of rehabilitation after stroke influence their outcome. Methods. A metaethnography of qualitative articles published since 2000 was undertaken. A systematic search of four databases using the keywords was competed. Original studies were included if at least 50% of their data from results was focused on stroke survivors experiences and if they reflected an overarching experience of stroke rehabilitation. Relevant papers were appraised for quality using the COREQ tool. Pata analysis as undertaken using traditional processes of extracting, interpreting, translating, and synthesizing the included studies. Results. Thirteen studies were included. Two themes (1 evolution of identity and (2 psychosocial constructs that influence experience were identified. A model of recovery was generated. Conclusion. The synthesis model conceptualizes how the recovery of stroke survivors’ sense of identity changes during rehabilitation illustrating changes and evolution over time. Positive experiences are shaped by key psychosocial concepts such as hope, social support, and rely on good self-efficacy which is influenced by both clinical staff and external support.

  5. Demodicose suína no norte do estado do Rio de Janeiro: relato de caso

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    R.L Silveira

    2012-06-01

    Full Text Available Um leitão oriundo de um criatório do norte do estado do Rio de Janeiro, mantido no biotério do Hospital Veterinário da Universidade Estadual do Norte Fluminense Darcy Ribeiro e utilizado como caso piloto de projeto de pesquisa para investigações sobre o acesso videolaparoscópico retal (NOTES - Natural Orifice Translumenal Endoscopic Surgery, foi eutanasiado e necropsiado. Amostras do ponto de acesso do tubo de inserção na região mucocutânea anal foram colhidas, fixadas em formalina neutra tamponada a 10%, processadas por inclusão em parafina e coradas pela hematoxilina e eosina para histologia. Observou-se o comprometimento de folículos que, dilatados, exibiam formações que lembravam Demodex spp. cortados em vários sentidos e, por se tratar de ácaros espécie-específicos, concluiu-se como D. phylloides. Na citopatologia, o ácaro foi recuperado e identificado a fresco, mostrando-se alongado, com quatro pares de patas ventrais e no terço anterior do corpo. Este se refere ao primeiro registro de demodicose suína no estado do Rio de Janeiro.

  6. Caracterização microbiológica e clínica de surtos de "red leg" em Minas Gerais e avaliação do efeito bactericida in vitro do Vantocil IB® para Aeromonas hydrophila Microbiological and clinical characterization of "red leg" outbreaks in Minas Gerais, Brazil, and evaluation of in vitro bacterial effects of Vantocil IB® for Aeromonas hydrophila

    Directory of Open Access Journals (Sweden)

    Anna Christina de Almeida

    2000-08-01

    Full Text Available Com o objetivo da caracterização da ocorrência de "red leg" em Minas Gerais, avaliaram-se rãs jovens e adultas que apresentavam úlceras nas patas e dedos, derrame hemorrágico na pele da região ventral, incoordenação motora, altas taxas de mortalidade em adultos e abscessos hepáticos à necropsia. No cultivo de fragmentos de pele lesada e abscessos, foi isolado e identificado Aeromonas hydrophila. O efeito bactericida do VANTOCIL IB® foi superior ao permanganato de potássio, determinado pela concentração inibitória mínima para colónias isoladas.With the objective of characterizating lhe ocurrence of "red leg" in Minas Gerais, Brazill, young and adult frogs which presented in theirpads and limbs hemorragie in the skin of the ventral region, incordination, high death rate in adults and hepatic abscess at necropsy, have been evaluated. In fragment culture ofdamage skin and abscess, Aeromonas. hydrophila hás been isolated and identified. The bactericidal effect of VANTOCIL IB® was higher than that of potassium permanganate, as determinated by the minimal inhibitory concentration for isolated colonies.

  7. Trasplante cardiaco

    Directory of Open Access Journals (Sweden)

    Donato Salas-Segura

    2008-12-01

    Full Text Available La insuficiencia cardiaca es un cuadro clínico frecuente y de apreciable mortalidad. A menudo de nuestra área de atracción emergen cardiópatas con diferentes grados de discapacidad, dependientes de familiares para su atención y que requieren re-hospitalizaciones y tratamientos costosos y a pesar de ello con mal pronóstico. Las autoridades sanitarias y particularmente el estado invierten anualmente mucho dinero en el tratamiento de los enfermos que la padecen y también en la cobertura de incapacidades para estos individuos. El trasplante cardiaco se ha implementado en el mundo como una excelente opción de tratamiento de los pacientes con insuficiencia cardiaca, capaz de brindar al menos 10 años de vida a pesar de lo riguroso del seguimiento, tanto para el paciente y su familia, como para el personal medico. El Hospital R. A. Calderón Guardia inició hace un año un Programa de Trasplante Cardiaco, presentamos aquí los 2 primeros pacientes y su seguimiento.

  8. Impacto de ondas sobre taludes

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    Yamile Valencia

    2003-01-01

    Full Text Available Las playas sufren cambios topobatimétricos por la acción del viento, corrientes, hidrodinámica del oleaje e inestabilidad de taludes. En este artículo se estudia un modelo, en donde es posible analizar la solución teórica tipo Airy del movimiento ondulatorio, para tipificar una onda que se produce por medio de un generador de oleaje, diseñado para operar en un canal metálico de determinadas dimensiones. En un extremo del canal fue construido un talud con y sin protecciones, de geometría inicial dada y con diversos materiales (arena gruesa, media, fina y limo-arenoso, el cual fue sometido a la acción de diferentes ondas y a un seguimiento en el tiempo, hasta llegar al perfil de equilibrio. Además, se estudió el proceso erosivo cuya principal característica es la socavación de la parte superior del talud y la depositación en la pata, así como la formación de un punto neutro o de “Cornaglia”.

  9. Hormonas de utilidad diagnóstica en Medicina Veterinaria Hormones of diagnostic value in Veterinary Medicine

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    R MATAMOROS

    2002-01-01

    Full Text Available Como muchas áreas de la medicina veterinaria, la endocrinología clínica ha experimentado importantes avances en el conocimiento de la fisiología, fisiopatología y el diagnóstico de las enfermedades en los animales domésticos. La presente revisión pretende entregar la información disponible, en la actualidad, de las pruebas endocrinas más relevantes de una manera concisa y práctica, tanto para los estudiantes de medicina veterinaria que están en su etapa de residencia clínica, como para los colegas que deseen más información sobre la determinación de condiciones fisiológicas y el diagnóstico diferencial entre alteraciones endocrinas y otras patAs many areas of the veterinary medicine, clinical endocrinology has experienced significant advances in the knowledge of physiology, physiopathology and the diagnosis of diseases in domestic animals. The present review seeks to provide an up-to-date information of most currently used endocrine tests in a concise and practical way for the students of veterinary medicine that are in their clinical residence and for the colleagues that want more information on the understanding of physiologic conditions and the differential diagnosis between endocrine disorders and other pathologies

  10. Enfermedades y entidades anímicas del entorno natural. Etiologías religioso-rituales y espacio-ambientales entre los toba del Chaco Central, Argentina

    Directory of Open Access Journals (Sweden)

    Gustavo J. Martínez

    2010-05-01

    Full Text Available El trabajo documenta, en el marco del estudio de la etnomedicina de los tobas del Chaco Central (Argentina, el rol que desempeñan entidades anímicas del monte chaqueño (plantas y animales en torno a los desequilibrios ambientales y religioso-rituales, esto es aquellos que devienen de la proximidad a ambientes negativos enfermantes, o bien de la transgresión de tabúes durante el ciclo vital y de trastornos en las relaciones con seres míticos. El material analizado proviene de la observación participante, entrevistas abiertas, extensas y en profundidad e instancias de investigación participativa, junto a la documentación de campo del material etnobiológico en cuestión. Asimismo se procura interpretar, desde el punto de vista de los nativos, aspectos vinculados con la nomenclatura vernácula, las representaciones etiológicas y las principales prácticas preventivas y terapéuticas de algunas de estas dolencias, tales como las odontalgias, los orzuelos, la conjuntivitis y otros taxa locales como “laiel” o pata de cabra, entre otros. Finalmente y a partir del material documentado se discuten algunos aspectos de la relación naturaleza-cultura evidenciados en la etnomedicina toba.

  11. [Biocultural study of infant malnutrition of primary cause in the urban setting of La Plata, Buenos Aires Province, Argentina].

    Science.gov (United States)

    Ortale, S; Rodrigo, M A

    1996-06-01

    The present study, of microsocial nature, attempts to recover the biology-culture unity in the analysis of child undernutrition. A sample was selected of 52 children with primary undernutrition and their families, from the population attending the Nutritional Rehabilitation Unit of La Plata Children Hospital. The specific index was used to measure the low socioeconomic level in families with undernourished children. The mothers were interviewed to obtain information on the perception and recognition of undernutrition. Observation and interviews to the medical staff were performed in ten centers of primary health care (PHC), in order to reveal the medical practices related to this problem. The results obtained showed that the studied families conjugated the most unfavorable life conditions within poverty. Children with adequate weight at birth were nutritionally affected between 3 and 18 months of age, leading to height disorders. The representations and practices sustained by the mothers, relating undernutrition to a popular disease named "pata de cabra" lead to limitations in treatment. In PHC centers, conceptual and operative limitations are recorded for its detection and early treatment. It is concluded that cultural factors present in the two most directly related agents to child health (the mother and the PHC center) do not allow to modify the environmental effects that prematurely affect the children of poverty.

  12. Informes psicológicos: el sujeto doble de la Psicología y el Derecho

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    Judit Bembibre-Serrano

    2006-01-01

    Full Text Available El objetivo de este estudio teórico es intentar establecer la naturaleza de algunas dificultades que enfrenta el psicólogo ante la elaboración de un informe pericial. Se centra en dos de ellas: la imposibilidad de una evaluación psicológica independiente del hecho jurídico y la confusión de la idea de sujeto que, en la práctica, tienen los diferentes tipos de profesionales implicados. Como consecuencia, asistimos a una psicologización de la Justicia, que proporciona tanto un elemento de control de los individuos como un mecanismo de conocimiento que oculta la naturaleza históricosocial subyacente a los trastornos psicológicos. En esta confusión, el juez se desdobla en terapeuta, mientras el psicólogo asume funciones de juez de instrucción y, en general, se vuelve a la concepción medieval al juzgar no el delito sino las características personales, como en el caso del psicópata. Se concluye que los problemas derivados de esta psicologización de la Justicia no tienen una solución técnica sino que requerirían una reformulación política del marco jurídico.

  13. La "Dea Artio" celta y la "Artemis" griega: Un aspecto religioso de la afinidad celto-iliria

    Directory of Open Access Journals (Sweden)

    Martín S. RUIPÉREZ

    2009-10-01

    Full Text Available En una partida de estatuillas romanas de bronce encontradas en 1832 en Muri, en las inmediaciones de Berna (Suiza, se hallaban una figura de osa, una diosa sentada teniendo una patera con frutas, una cesta, un árbol tortuoso y un pedestal con la inscripción Deae Artioni/ Licinia Sabinilla. En seguida se vio que la diosa, el cesto y el árbol tenían su sitio señalado en el pedestal, pero hasta 1899 no se reconstruyó el grupo en su integridad al probar Vionnet que las patas de la osa habían dejado su huella sobre el pedestal, entre el árbol y la diosa (ver grabado adjunto. La inscripción aparece recogida en CIL, XI11, 5.160, y el grupo escultórico fue publicado por S. Reinach, Revue Celtique, 21, 1900, p. 288, en un artículo, al que nos referiremos después, sobre "Les survivances du totémisme chez les anciens Celtes".

  14. 福建安溪不同年限茶树土壤养分与微生物Biolog功能多样性的差异分析%Analysis of nutrient and microbial Biolog function diversity in tea soils with different planting years in Fujian Anxi

    Institute of Scientific and Technical Information of China (English)

    林生; 庄家强; 陈婷; 张爱加; 周明明; 林文雄

    2012-01-01

    Premature aging and degradation of tea gardens have been critical issues limiting the economic development of tea industry. Nutrient and microbial diversity in tea garden soils with different planting years were studied. The study was based on pH and fertility indexes of tea producing environmental conditions (NY/T8 53—2004). Soil pH of 1-year-old tea was 4.73, which was at grade H level. Also soil pH of 6-year-old tea was 4.41, close to grade II. Both these grades conformed to acid-base indicators for high quality tea garden soils. The soil pH of 20-year-old tea was 4.15 (less than 4.5 but close to 4.0) and therefore identified as acidic. Organic matter, available N (nitrogen) and available P (phosphorus) in the 6-year-old tea soil were respectively at fertility grade I level. That of available K (potassium) was at grade III level. Available P was abundant in the 1-year-old tea soil, which was at grade I level. While available N was at grade II, organic matter and available K were at grade HI level. In the 20-year-old tea soil, organic matter reached grade II and available N, P and K reached grade HI. While the 6-year-old tea soil fertility was the best, 1-year-old tea soil fertility was medium and then the 20-year-old tea soil fertility was the worst. Biolog analysis showed that the ability of microbial flora to use six kinds of carbon sources was highest in the 6-year-old tea soil. It was lowest in the 20-year-old tea soil. Microbial utilization of six kinds of carbon sources in the 1-year-old tea soil was moderate. Community diversity indexesanalysis showed that the Shannon index, Brillouin index, homogeneity index and richness index of the 6-year-old tea soil were the highest. These indexes were worst in the 20-year-old tea soil. Compared with the 6- and 1-year-old tea soils, the 20-year-old tea soil presented the strongest acidification. Organic matter in the 20-year-old tea soil was 47.81% less than that in the 6-year-old tea soil. Physiological activity

  15. 不同林龄杂交楝(Azadirachta indica× Melia azedarach)人工林土壤水土保持功能研究%Soil and Water Conservation Functions of Azadirachta indica×Melia azedarach Plantation at Different Ages

    Institute of Scientific and Technical Information of China (English)

    成向荣; 虞木奎; 周卫兵; 何祯祥

    2012-01-01

    为了明确林龄对杂交楝(印楝×苦楝)人工林土壤水土保持功能的影响,通过测定土壤持水能力、渗透能力和抗蚀能力来综合评价不同林龄杂交楝人工林保持水土功能.结果表明,随着杂交楝林龄增加,林地土壤孔隙结构得到改善、持水性能增加、渗透能力增大,提高了土壤水稳性指数,增加了土壤抗蚀性,土壤水土保持功能得到增强.3年生杂交楝林分的土壤持水性能、渗透能力和抗蚀性与1年生林分之间无显著差异,5年生杂交楝林地各指标均比1年生和3年生林分有显著提高.5年生杂交楝林地的土壤最大持水量、总孔隙度、非毛管孔隙度、平均渗透速率和水稳性指数分别比1年生林地增加18.6%、11.4%、19.8%、45%、30.1%.因此,种植杂交楝可以在短期内提高林分的土壤水土保持功能,在山地丘陵地区值得大力发展杂交楝.%In order to evaluate the effect of forest age of Azadirachta indica×Melia azedarach (hybrid neem tree) plantation on soil and water conservation function, soil water-holding capacity, infiltration capacity and erosion resistance of hybrid neem plantation in different ages were studied. The results showed that soil pore structure, soil water-holding capacity, infiltration capacity, and soil erosion resistance increased with the increase of hybrid neem stand age, soil and water conservation function was further enhanced. Soil water-holding capacity, infiltration capacity, and soil erosion resistance were not significant difference between 3-year-old and 1-year-old hybrid neem stands, however, these variables of the 5-year-old hybrid neem stand were significantly higher than that of 1-year-old and 3-year-old stands. Compared to 1-year-old stand, maximal soil water-holding capacity, total porosity, non-capillary porosity, the average infiltration rate and water stability index of the 5-year-old hybrid neem stand increased by 18.6%, 11.4%, 19.8%, 45

  16. Efeito da mosca-dos-chifres, Haematobia irritans (L. (Diptera: Muscidae, no ganho de peso de bovinos Nelore Effects of the horn fly, Haematobia irritans (L. (Diptera: Muscidae in the weight gain on Nellore cattle

    Directory of Open Access Journals (Sweden)

    Ivo Bianchin

    2004-06-01

    Full Text Available A presente investigação foi realizada devido à escassez, no Brasil, de informações sobre os possíveis danos decorrentes da ação hematófaga da mosca-dos-chifres, Haematobia irritans (L., em bovinos da raça Nelore. O estudo foi realizado durante quatro estações chuvosas (outubro a abril, de 1991 a 1995. Em cada ano, 80 bovinos foram utilizados de acordo com os seguintes tratamentos: 28 touros com um ano de idade divididos em quatro grupos; 20 bois com idade de dois anos divididos em quatro grupos, e 32 bois com três anos e divididos em oito grupos. Metade dos grupos de animais de cada idade eram tratados contra H. irritans com intervalos de 28 dias e os demais mantidos como grupos controle. As moscas foram contadas a cada 14 dias e o peso dos bois registrado a cada 28. O número médio de mosca/animal dos grupos controle para o primeiro, segundo, terceiro e quarto anos do estudo foi, respectivamente: cinco, cinco, quatro e cinco, nos animais de um ano; 15, 11, 13 e 27, nos de dois anos e 55, 31, 40 e 51, nos de três anos. Observou-se que maior número de moscas (PThis investigation was carried out due the lack of information about the possible effects of the blood-feeding horn fly, Haematobia irritans (L., on Nellore cattle. Data were recorded during four rainy seasons (October to April from 1991 to 1995. In each year, 80 animals were utilized according to the following treatments: twenty-eight 1-year old bulls divided into four groups; twenty 2-year old cattle divided into four groups and thirty-two 3-year old cattle divided into eight groups. Treatments against H. irritans were conduced at about 28-day intervals on half part of each age groups and the remainders groups maintained without treatment as control. The flies were counted at 14-day intervals and the animals weight registered at each 28-day intervals. The values for the mean flies number on the animals of the control groups in the first, second, third and fourth years of

  17. Predictors of ante-natal care, delivery and infant feeding practices among rural women in Madhya Pradesh, India

    Directory of Open Access Journals (Sweden)

    Indrapal Ishwarji Meshram

    2014-10-01

    Full Text Available Background: Maternal and infant mortality rates and prevalence of under nutrition are high in the State Madhya Pradesh. Regular ante-natal check-ups (ANC, delivery by trained health personnel, delivery practices and optimal infant feeding practices are important to reduce maternal and infant mortality. Objectives: The aim was to assess antenatal care, delivery and infant feeding practices of mothers of <1-year-old children in Madhya Pradesh. Materials and Methods: This was community-based cross-sectional study carried out in the rural areas of Madhya Pradesh by adopting systematic random sampling procedure. Data were collected from 5324 mothers having <1-year-old children. Information on household (HH socioeconomic and demographic particulars was collected from the mothers. Bivariate and multivariate analysis was performed to study the association between dependent and independent variables. Results and Interpretations: About 36% mothers had undergone at least three ante-natal check-ups and 73% delivered either at government or private hospitals. Only 26% mothers initiated breastfeeding within 1-h of birth and 92% fed colostrum. Step-wise regression analysis showed that ante-natal care for <3 times was significantly (P < 0.01 higher among women with high parity (≥5, illiterate women, and among lower socioeconomic group,s while home delivery was higher among women with high parity (≥5 (odds ratio [OR]: 2.3, among Scheduled Caste and Tribe women (OR: 1.5, illiteracy of head of HH (OR: 2, and among lower socioeconomic groups (OR: 1.3. Discarding colostrum was higher among illiterate women (OR: 1.6, belonging to lower socioeconomic groups (OR: 1.4 and delivery conducted by untrained person (OR: 3.9, while initiation of breastfeeding after 1-h of childbirth was higher among ≥30 years women (OR: 1.9, illiterate women (OR: 1.4, and delivery by untrained person (OR: 2.9. Conclusions: It was observed that antenatal care, delivery and infant and

  18. Time Course Analysis of Skeletal Muscle Pathology of GDE5 Transgenic Mouse

    Science.gov (United States)

    Yoshizawa, Ikumi; Kajihara, Kaori; Kato, Norihisa; Wada, Masanobu; Yanaka, Noriyuki

    2016-01-01

    Glycerophosphodiesterase 5 (GDE5) selectively hydrolyses glycerophosphocholine to choline and is highly expressed in type II fiber-rich skeletal muscles. We have previously generated that a truncated mutant of GDE5 (GDE5dC471) that lacks phosphodiesterase activity and shown that transgenic mice overexpressing GDE5dC471 in skeletal muscles show less skeletal muscle mass than control mice. However, the molecular mechanism and pathophysiological features underlying decreased skeletal muscle mass in GDE5dC471 mice remain unclear. In this study, we characterized the skeletal muscle disorder throughout development and investigated the primary cause of muscle atrophy. While type I fiber-rich soleus muscle mass was not altered in GDE5dC471 mice, type II fiber-rich muscle mass was reduced in 8-week-old GDE5dC471 mice. Type II fiber-rich muscle mass continued to decrease irreversibly in 1-year-old transgenic mice with an increase in apoptotic cell. Adipose tissue weight and blood triglyceride levels in 8-week-old and 1-year-old transgenic mice were higher than those in control mice. This study also demonstrated compensatory mRNA expression of neuromuscular junction (NMJ) components, including nicotinic acetylcholine receptors (α1, γ, and ε subunits) and acetylcholinesterase in type II fiber-rich quadriceps muscles in GDE5dC471 mice. However, we did not observe morphological changes in NMJs associated with skeletal muscle atrophy in GDE5dC471 mice. We also found that HSP70 protein levels are significantly increased in the skeletal muscles of 2-week-old GDE5dC471 mice and in mouse myoblastic C2C12 cells overexpressing GDE5dC471. These findings suggest that GDE5dC471 mouse is a novel model of early-onset irreversible type II fiber-rich myopathy associated with cellular stress. PMID:27658304

  19. Research on Early Diagnosis and Intervention of Infantile Brain Injury%婴儿脑损伤早期诊断和早期干预的研究

    Institute of Scientific and Technical Information of China (English)

    张粤蓝

    2013-01-01

    Objective: To explore the early diagnosis and intervention of infantile brain injury. Methods: Clinical data of infantile brain injury in 96 cases were retrospectively analyzed from March 2010 to March 2012. Results:Monitoring infants of high risk is helpful to find out infantile brain injury, the discovery rate in hospital accounted for 83.33%, and 16.67%at home;Premature birth, threatened abortion and hyperbilirubinemia were the risky factors of top three;Sick infants less than 1 years old were mainly CCD and stunt, and infants more than 1 years old were mainly hypophrenia, CP, CP+MR and CP+EP. After 1~2 courses of synthetical in-tervention in early stage, the total effective rate was 90.63%, and the curative effects of infantile brain injury in 1~3 months was the best. Conclusion:Dynamic neural monitoring of infantile brain injury is conducive to early diagnosis, early intervention can promote early brain injury recovery and improve the prognosis quality.%  目的:探究婴儿脑损伤早期诊断和早期干预。方法:回顾性分析2010年3月~2012年3月我院诊治的96例婴儿脑损伤的临床资料。结果:对高危患儿进行监测有助于早期发现脑损伤患儿,其中院内发现占83.33%,家庭中发现占16.67%;前三位高危因素为早产、先兆流产、高胆红素血症;1岁者主要以CP、智力低下、CP+MR、CP+EP为主。经综合早期干预1~2个疗程后,总有效率为90.63%,其中1~3个月的患儿治疗效果最好。结论:对婴儿进行脑损伤动态神经监测,有利于早期诊断,及早干预,促进早期脑损伤修复,改善预后质量。

  20. Follow-up on lack of Vitamin D deficiency and poisoning after the supplementation of vitamin D%维生素D预防应用后儿童维生素D缺乏及中毒情况随访

    Institute of Scientific and Technical Information of China (English)

    李红梅; 黄萍; 宋芳; 庞希莲

    2014-01-01

    Objective:To follow up Vitamin D deficiency and poisoning of 0~1 year-old infants after vitamin D supplementation.Methods: 500 children for child’s care from January 2011 to January 2013 were taken VitD at the half month, and regularly followed up. At the age of half year and 1 year-old, the functions of blood and liver, alkaline phosphatase, calcium, C-reactive protein were tested. Results:After oral administration of vitamin D, the incidence of rickets prevalence was very low, and in early stage without typical clinical manifestations. They can return to normal after treatment of vitamin D3 without vitamin D intoxication. Conclusion:In clinical practice, vitamin D500-1000 units can bot only prevent vitamin D deficiency,but prevent intoxication.%目的:随访0~1岁婴儿补充维生素D后维生素D缺乏及中毒的情况。方法:2011年1月~2013年1月对前来进行儿童保健的500名儿童在半月时开始补充VitD,并定期随访,于6月及1岁时分别进行血肝功、碱性磷酸酶、钙、磷及C反应蛋白的化验检查。结果:经过口服维生素D预防后佝偻病的患病率极低,且均为早期,无典型临床表现,予以维生素D3治疗后基本上都恢复正常;无维生素D中毒。结论:临床工作中补充维生素D500-1000单位既可预防维生素D缺乏,又不会出现维生素D中毒。

  1. Children's mouthing and food-handling behavior in an agricultural community on the US/Mexico border.

    Science.gov (United States)

    Black, Kathleen; Shalat, Stuart L; Freeman, Natalie C G; Jimenez, Marta; Donnelly, Kirby C; Calvin, James A

    2005-05-01

    Children's mouthing and food-handling activities were measured during a study of nondietary ingestion of pesticides in a south Texas community. Mouthing data on 52 children, ranging in age from 7 to 53 months, were collected using questionnaires and videotaping. Data on children's play and hand-washing habits were also collected. Children were grouped into four age categories: infants (7-12 months), 1-year-olds (13-24 months), 2-year-olds (25-36 months) and preschoolers (37-53 months). The frequency and type of events prompting hand washing did not vary by age category except for hand washing after using the bathroom; this increased with increasing age category. Reported contact with grass and dirt also increased with increasing age category. The median hourly hand-to-mouth frequency for the four age groups ranged from 9.9 to 19.4, with 2-year-olds having the lowest frequency and preschoolers having the highest. The median hourly object to mouth frequency ranged from 5.5 to 18.1 across the four age categories; the frequency decreased as age increased (adjusted R(2)=0.179; P=0.003). The median hourly hand-to-food frequency for the four age groups ranged from 10.0 to 16.1, with the highest frequency being observed in the 1-year-olds. Hand-to-mouth frequency was associated with food contact frequency, particularly for children over 12 months of age (adjusted R(2)=0.291; P=0.002). The frequency and duration of hand-to-mouth, object-to-mouth and food-handling behaviors were all greater indoors than outdoors. Infants were more likely to remain indoors than children in other age groups. The time children spent playing on the floor decreased with increasing age (adjusted R(2)=0.096; P=0.031). Parental assessment was correlated with hand-to-mouth activity but not with object-to-mouth activity. The highest combined (hand and object) mouthing rates were observed among infants, suggesting that this age group has the greatest potential for exposure to environmental toxins. PMID

  2. Ameliorative potential of Butea monosperma on chronic constriction injury of sciatic nerve induced neuropathic pain in rats

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    Venkata R.K. Thiagarajan

    2012-12-01

    Full Text Available The present study was designed to investigate the ameliorative role of ethanolic extract from leaves of Butea monosperma in chronic constriction injury (CCI of sciatic nerve induced neuropathic pain in rats. Hot plate, acetone drop, paw pressure, Von Frey hair and tail immersion tests were performed to assess the degree of thermal hyperalgesia, cold chemical allodynia, mechanical hyperalgesia & allodynia in the left hind paw and tail thermal hyperalgesia. Further on, thiobarbituric acid reactive substances (TBARS, reduced glutathione (GSH and total calcium levels were estimated to assess the biochemical changes in the sciatic nerve tissue. Histopathological changes were also observed in the sciatic nerve tissue. Ethanolic extract of Butea monosperma leaves and pregabalin (serving as positive control were administered for 14 consecutive days starting from the day of surgery. CCI resulted in significant changes in behavioural and biochemical parameters. Pretreatment of Butea monosperma attenuated CCI induced development of behavioural, biochemical and histopathological alterations in a dose dependent manner, which is comparable to that of pregabalin pretreated group. These findings may be attributed to its potential anti-oxidative, neuroprotective and calcium channel modulatory actions of Butea monosperma.O presente trabalho visou investigar o papel do extrato etanólico de folhas de Butea monosperma no alívio da dor neuropática pela injúria de constrição crônica (CCI do nervo ciático induzida em ratos. Placa quente, gota de acetona, pressão na pata, testes de imersão de pelo e cauda de Von Frey foram utilizados para acessar o grau de hiperalgesia térmica, alodinia química fria, hiperalgesia mecânica e alodinia na pata trazeira esquerda e hiperalgesia térmica da cauda. Além disso, substâncias reativas com ácido tiobarbitúrico (TBARS, glutatião reduzido (GSH e níveis de cálcio total foram estimados para acessar as altera

  3. Analysis of the use of fenthion via epicutaneous in dogs for Rhipicephalus sanguineus control Análise do uso de fenthion via epicutânea em cães para o controle de Rhipicephalus sanguineus

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    Fernando de Freitas Fernandes

    2001-01-01

    Full Text Available The action of fenthion was studied in a 15% epicutaneous formulation upon Rhipicephalus sanguineus, which may transmit pathogens to men and other animals, such as Ehrlichia, Babesia and Ricketsia. Dogs were artificially infected for the trial. The fenthion bioassays were begun four months after artificial infestation. The test group, having a mean of 186 ticks per dog, received the formulation dosage according to body weight on the neck region. Tick counts were performed, considering diameters > or = 2mm, during 11 days of treatment, in the most affected body areas: back, ears and paws. Before the application of fenthion in the dogs, it were observed an average 43.3% ticks in the ears, 38.1% in the back area and 17.6% in the paws. The number of ticks in dogs decreased by 36.2%, 63.8%, 82.7%, 67%, 40% and 4.9%, respectively on days 1, 2, 3, 5, 7, 9 and 11 after treatment. R. sanguineus anti-tick activity, lower than that officially recommended, was verified. The number of ticks increased progressively after the 5th day, demonstrating residual insecticide inefficacy. The results obtained did not indicate the use of this formulation, at the tested dosage, as an elective measure for R. sanguineus control.Investigou-se a atividade de fenthion em formulação epicutânea a 15% sobre Rhipicephalus sanguineus, transmissor de patógenos ao homem e animais, tais como Ehrlichia, Babesia e Ricketsia. Infestou-se artificialmente cães com larvas deste carrapato. Os bioensaios com o fenthion iniciaram-se 4 meses após a infestação artificial. Constatada a média de 186 ixodídeos/cão, cães do grupo teste receberam na região da nuca a dosagem correspondente ao seu peso. Avaliaram-se a eficiência e a atividade residual através de contagens dos carrapatos com diâmetro > ou = 2mm, durante 11 dias, nas áreas corpóreas mais parasitadas: dorso, orelhas e patas. Anteriormente, à aplicação do fenthion, 44,3% dos carrapatos format observados nas orelhas

  4. A new proposal to evaluate the healing of open skin wounds: volumetry Nova proposta para avaliar cicatrização de ferida cutânea aberta: volumetria

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    Danilo Nagib Salomão Paulo

    2011-12-01

    Full Text Available PURPOSE: To present a new proposal to evaluate the healing of an open subcutaneous and skin wound, which we termed "volumetry". METHODS: A total of 32 circular wounds were performed in the subcutaneous tissues and skin of four feet of pigs (8 each. Each wound had about 1 cm in diameter and was 0.2 cm deep. Volume was calculated from the wound filled with saline and mass Xantopren. With the aid of a magnifying glass and local lighting, the liquid was dripped with a micropipette inside the wound until complete fullness. Volume repletion was calculated in microliters, corresponding to the volume of the wound. The mass of Xantopren was placed inside the wound to obtain a mold of the lesion. Mold volume was calculated using the formula of the volume of a cylinder closest resembling a geometric figure with mold. RESULTS: The calculation of wound volume was possible with both Xantopren and mold techniques. Volume as calculated by micropipette was 119.37 ± 30.87 microliters while the volume calculated by mold was 122.41 ± 33.90 mm3 (p=0.79. CONCLUSIONS: Volumetry in pig feet is simple and reproducible. Volumetry perfomed with saline did not differ from the volumetry with mass Xantopren. This method may be a useful tool to help evaluate the healing of open skin wounds in experimental and clinical research.OBJETIVO: Apresentar nova proposta para avaliar a cicatrização de uma ferida cutânea aberta, denominada "volumetria." MÉTODOS: Foram provocadas 32 feridas circulares cutâneas, com cerca de 1 cm de diâmetro e 0.2 cm de profundidade, em quatro patas de suíno. O volume da ferida foi calculado com solução salina e massa de xantopren. O líquido foi gotejado com uma micropipeta no interior da ferida até sua completa repleção, o que foi auxiliado com uma lupa de aumento e iluminação local. O volume de repleção foi calculado em microlitros e correspondeu ao volume da ferida. A massa de xantopren foi colocada no interior da ferida para se

  5. O ultrassom terapêutico na medula espinhal acelera a regeneração do nervo ciático de ratos Therapeutic ultrasound on the spinal cord accelerates regeneration of the sciatic nerve in rats

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    Fernanda Guadallini Jatte

    2011-01-01

    Full Text Available OBJETIVO: Estudar os efeitos da irradiação ultrassônica de baixa intensidade aplicada sobre a medula espinhal na regeneração do nervo ciático de ratos após lesão por esmagamento controlado, avaliando os resultados pelo índice funcional do ciático (SFI, medido nas imagens vídeo-filmadas das plantas das patas. MÉTODOS: Dezoito ratos foram submetidos a esmagamento controlado (do nervo ciático direito e divididos em dois grupos de acordo com o tratamento: Grupo 1 (n=9, irradiação simulada; Grupo 2 (n=9, irradiação efetiva. Irradiação ultrassônica de baixa intensidade foi iniciada no 7º dia pós-operatório e aplicada diariamente por 6 semanas. Imagens das plantas das patas dos animais foram vídeo-filmadas em uma esteira transparente sob velocidade controlada a intervalos semanais até a 6ª semana de irradiação e o correspondente SFI medido com um programa de computador específico. RESULTADOS: O SFI durante a 1ª e a 6ª semana de tratamento foi de -59,12 e -12,55 no Grupo 1, e -53,31 e -1,32 no Grupo 2, indicando uma melhora de 79% e 97%, respectivamente, mas as diferenças entre os grupos somente foram significantes (pOBJECTIVE: To study the effects of low intensity ultrasound irradiation applied on the spinal cord on the regeneration of the rat's sciatic nerve after a controlled crush injury, evaluating the functional results of the sciatic functional index as measured on the video recorded images of the foot sole. METHODS: Eighteen rats were submitted to a controlled crush injury of the right sciatic nerve and divided into two groups according to the treatment: Group 1 (n=9, simulated irradiation; Group 2 (n=9, effective irradiation. Low-intensity ultrasound irradiation was started on the 7th postoperative day and applied daily for 6 weeks. Images of the animals´ foot sole were video recorded on a see-through treadmill type walking belt machine at weekly intervals until the 6th week of irradiation and the corresponding

  6. Removal new alternative to chemical and mechanical removal for the study of pollen carried on the wild bee scopae Remoción química como nueva alternativa a la remoción mecánica para el estudio del polen transportado en las escopas de abejas silvestres

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    Marta Caccavari

    2010-12-01

    Full Text Available Taxonomic recognition and quantification of the different pollen types collected by bees offer the most direct method to study the diet. To determine the importance of each plant taxon, it is necessary to separate the pollen deposited only in the collecting structures in order to minimize contamination of grains collected passively in other parts of the body. The technique currently applied is based on the mechanical removal of the pollen loads with dissecting needles and repeated washings with ethanol. Metathoracic scopae that underwent this procedure showed traces of pollen in varying amounts when observed under the microscope. As an alternative to this technique chemical removal using HOK is proposed. The leg is removed and treated separatedly to avoid contamination. The deflocculant properties of HOK successfully allowed to separate the pollen adhered to the scopae, which can be then returned to the individual, unaffected by the procedure. Suspend the pollen in a know quantity of mounting fluid permit take the subsamples and determine the total number of pollen grains of each taxon. In this paper, the new technique is presented and its effectiveness is compared to the technique currenty used.El reconocimiento taxonómico y la cuantificación de los distintos tipos polínicos colectados por las abejas ofrecen el método más directo para estudiar la dieta. Para determinar la importancia de cada taxón vegetal y minimizar la contaminación, es necesario separar el polen depositado en las estructuras de colecta, de los granos recolectados en forma pasiva en otras partes del cuerpo. La técnica que se aplica hasta el momento se basa en la remoción mecánica de las cargas polínicas con agujas de disección y sucesivos lavados con etanol. Escopas de patas metatoráxicas sometidas a este procedimiento al ser observadas bajo lupa presentaban aún granos de polen en cantidades variables. Como una alternativa a esta técnica proponemos la remoci

  7. Toxicity of Field-Aged Permethrin-Loaded Attracticides on Choristoneura rosaceana (HARRIS and Pandemis pyrusana Kearfott (Lepidoptera: Tortricidae Adult Males and Females Toxicidad de Atracticidas en Base a Permetrina Envejecidos en Campo, sobre Machos y Hembras Adultas de Choristoneura rosaceana (Harris and Pandemis pyrusana Kearfott (Lepidoptera: Tortricidae

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    Tomislav Curkovic

    2009-03-01

    ,3% luego del emparejamiento con machos intoxicados. Veinticuatro h post exposición el nivel de auto amputación de patas en machos expuestos al atracticida fue al menos 73% en C. rosaceana y ≥ 41% en P. pyrusana, mientras que fue ≥ 10% entre hembras de ambas especies luego del emparejamiento con machos intoxicados. Las polillas expuestas a un atracticida “blanco” (sin permetrina mostraron niveles significativamente menores en todos los parámetros evaluados (0-3,3%. La fecundidad y fertilidad también fueron significativamente afectadas por el emparejamiento con machos intoxicados. No se observó una reducción significativa en la mortalidad, auto-amputación de patas ni en la fecundidad asociada al tiempo que fue envejecido el atracticida. Los resultados sugieren un alto potencial para el uso de atracticidas contra estas dos especies de tortrícidos.

  8. Redução do efeito analgésico da estimulação elétrica nervosa transcutânea de baixa freqüência em ratos tolerantes à morfina Reduction in analgesic effect from low-frequency transcutaneous electrical nerve stimulation in morphine-tolerant rats

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    MA Resende

    2006-09-01

    Full Text Available OBJETIVO: Investigar o efeito da TENS de baixa (10 Hz e alta freqüência(130 Hz aplicadas na pata inflamada do rato após tratamento crônico com morfina. MÉTODO: Foram utilizados 140 ratos Holtzman fêmeas, nos quais a carragenina (Cg 250 µg/0,1ml foi administrada na pata posterior direita para a indução da inflamação. TENS de baixa e alta freqüência foi aplicada por 20 min, após 2 h e 30 min da Cg e seu efeito medido através do método de Randall-Selitto. O antagonista opióide Naltrexona (3mg/kg,sc, foi administrado 30 minutos antes da TENS para verificar a liberação de substâncias opióides endógenas. A tolerância foi obtida após administração da morfina (10 mg/kg,sc, duas vezes ao dia, durante sete dias. O tratamento com TENS de baixa e alta freqüência foi realizado no oitavo dia às 2 h e 30 min após Cg. A análise estatística foi feita pelo método da análise de variância ANOVA (One Way seguido de um teste "post hoc" (Teste de Bonferroni, com nível de significância quando p OBJECTIVE: To investigate the effects of low (10 Hz and high-frequency (130 Hz transcutaneous electrical nerve stimulation (TENS applied to inflamed paws of rats following chronic treatment with morphine. METHOD: 140 female Holtzman rats were utilized. Carrageenan (250 µg/0.1 ml was administered to the right hind paws to induce inflammation. Two and a half hours after carrageenan injection, low and high frequency TENS was applied to the inflamed paw for 20 min, and its effect was measured via the Randall-Selitto method. The opioid antagonist naltrexone (3.0 mg/kg, subcutaneously was administered 30 min before TENS, to verify the release of endogenous opioids. Morphine tolerance (10 mg/kg, subcutaneously was induced by twice-daily injection over seven days. Low and high frequency TENS treatment was carried out on the eighth day, 2.5 hours after carrageenan injection. Statistical analysis was performed using one-way analysis of variance (ANOVA

  9. Estudo histomorfométrico do músculo esquelético de ratos em anestro Skeletal muscle histomorphometric study of rats in anestrus

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    Manoel de Almeida Moreira

    2005-08-01

    Full Text Available A castração, assim como a menopausa, representa estágio de supressão endócrina em que prevalece o hipoestrogenismo e sua conseqüência maior sobre o músculo esquelético é provocar sarcopenia. OBJETIVOS: estudar as alterações histomorfológicas do músculo esquelético de ratos fêmeas castrados. MÉTODOS: vinte e seis ratos Wistar, distribuídos em dois grupos, A e B, submetidos inicialmente à pesagem, citologia vaginal, ovariectomia e biópsia do músculo rectus femoris das patas traseiras, grupo A na direita e B na esquerda. Decorridos 20 dias foi colhido citologia vaginal para comprovar o estado de anestro. Após 70 dias os animais foram pesados e passaram por biópsia muscular, grupo A na pata E e grupo B na D. A histomorfometria foi realizada com o auxílio de uma lente gradiculada de 1cm², com retículo de Weibel de 1mm²; contou-se as miofibrilas com seis leituras na vertical e cinco na horizontal em cada lamina, obtendo-se um número múltiplo que aplicado sobre uma formula especifica para calcular o Coeficiente de Densidade Muscular. RESULTADOS: em A a densidade muscular variou de 60.0 para 52.33 (pCastration, as well as the menopause, represents endocrine suppression that prevails the hipoestrogenism and their larger consequence on the skeletal muscle is to provoke sarcopenia. OBJETIVE: To study the morphometric alteration of striated muscle of castrated female rats. METHODS: Twenty six female rats Wistar , distributed in two sub-groups, A and B, submitted initially to weigh-in place, vaginal cytology, ovariectomy, and biopsy of the muscle rectus femoris on the back paws, A group on right paw, and B on the left. Elapsed 20 days it was collected vaginal cytology to prove the anestrus status. After 70 days the animals went through weigh-in place, and new muscle biopsy, A group in left paw and B in right paw. The morphometric study was accomplished with the aids of a graduated lens, with reticules of 100 mm², it was counted

  10. Regeneração in vitro via organogênese direta de Bauhinia cheilantha In vitro regeneration of the Bauhinia cheilantha via organogenesis

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    Ingrid Estefania Mancia de Gutiérrez

    2011-02-01

    Full Text Available Bauhinia cheilantha, conhecida como "pata-de-vaca", possui grande relevância econômica e etnofarmacológica no semiárido brasileiro. Nas suas sementes constatou-se dormência, o que dificulta a obtenção de plantas uniformes e em curto período de tempo, diante disso, o presente trabalho objetivou estabelecer um protocolo de micropropagação para a espécie. Os segmentos cotiledonar e nodal de plântulas emergidas in vitro foram inoculados em meio de cultura WPM, suplementado com diferentes concentrações de 6-benzilaminopurina (BAP, thidiazuron (TDZ ou cinetina (KIN para induzir a regeneração de brotos adventícios. Na fase de enraizamento foram testadas diferentes concentrações de ácido indol-3-butírico (AIB e de carvão ativado. Nos segmentos nodais houve maior capacidade organogênica do que no segmento cotiledonar. O maior número de brotos (4,3 e 2,1 foi obtido com 1,0mg L-1 de TDZ e 1,5mg L-1 de BAP, respectivamente. No entanto, na presença de TDZ foram observadas as menores brotações. A presença de 2,0mg L-1 de AIB com carvão ativado (CA promoveu a maior porcentagem de enraizamento (cerca de 60,0% e maior número de raízes adventícias (2,5. As brotações enraizadas foram transferidas para casa de vegetação e aclimatizadas com sucesso.Bauhinia cheilantha, known as "pata-de-vaca", is of great economic and ethnopharmacological importance in the semiarid Brazilian. Seeds are dormant which makes it difficult to obtain uniform plants in a short time before this, our study aimed to establish a micropropagation protocol for the species. Cotyledonary and nodal segments of seedlings grown in vitro were inoculated on Woody Plant Medium (WPM supplemented with various concentrations of 6-benzylaminopurine (BAP, thidiazuron (TDZ or kinetin (KN to induce adventitious shoot regeneration. In the rooting phase, different concentrations of indole-3-butyric acid (IBA and the activated charcoal were tested. The nodal segments showed

  11. Characterization of Pregnant Women with Heart Disease at the “Ramón Gonzalez Coro” Gynecologic and Obstetric Teaching Hospital Caracterización de las gestantes con cardiopatías en el Hospital Docente Ginecobstétrico “Ramón González Coro”

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    Yanara Gutierrez Aliaga

    2011-11-01

    Full Text Available Introduction: pregnancy-related heart disease is nowadays the first cause of maternal morbidity and mortality among pregnancy-related pathologies. Objective: to characterize pregnant women with heart disease according to demographic and clinical features. Method: a descriptive study with some analytic aspects was conducted in the Heart Disease and Pregnancy service of “Ramón Gonzalez Coro’’ Gynecologic and Obstetric Teaching Hospital from 2000-2009. The universe consisted on the 472 pregnant women with heart disease that received follow up during that period. They were treated according to the protocol applied since 2000. Data were obtained through a questionnaire and were processed using the SPSS 11,5 system for Windows, through determination of absolute and relative frequencies. They included: mothers’ age, first and third trimester functional classification, drugs used and cardiovascular complications. Results: valvular heart diseases (25, 6 % were the most common type of heart disease. Important modifications were found at the end of pregnancy for the functional degree. Complications were registered in 29,9 % of patients, being pulmonary acute edema (6,4 %, cardiac arrest (4,3 % and arrhythmias (3,5 %, the most common ones. Pulmonary thomboembolism was the cause of the two maternal deaths that occurred. Conclusion: valvular heart diseases were the most common cardiac disease detected in the patients included in our study. Most of them were classified as functional degree I, being pregnancy a potential risk for them.Introducción: el embarazo en las mujeres cardiópatas constituye hoy, la primera causa de morbi-mortalidad materna entre las patologías asociadas al embarazo. Objetivo: caracterizar a las gestantes con cardiopatía desde el punto de vista clínico y demográfico. Método: estudio

  12. Evaluation of anti-ulcerogenic activity in an Aqueous Extract obtained from Bauhinia forficata leaves

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    Giovanna Christina Costa Mazzeo

    2015-09-01

    Full Text Available Bauhinia forficata Link, popularly known as pata-de-vaca, unha-de-vaca, casco-de-vaca, has been widely used in traditional medicine to treat several diseases. Leaves of B. forficata are used in popular medicine as a diuretic, hypoglycemic, tonic and cleanser, and to combat elephantiasis. However, despite the wide range of ethnopharmacological data surrounding the plant, there are no scientific data demonstrating a probable anti-ulcerogenic activity conferred by use of that species. The present study aimed to evaluate the antiulcer properties of an infusion of fresh leaves of B. forficata Link. From the leaves of B. forficata, an Aqueous extract (AqE was obtained and the phytochemical analysis showed the presence of flavonols in this extract. In the gastric ulcer induced by administration of HCl-Ethanol model performed with four different doses of AqE (125, 250, 500 and 1000 mg.Kg-1, the AqE showed significant preventive activity (*p<0.01 at doses of 1000 mg.Kg-1. The antiulcer activity of AqE (1000 mg.Kg-1 could also be demonstrated in experimental models of NSAID-bethanechol (**p<0.001 and absolute ethanol (**p<0.001. Moreover, AqE (1000 mg.Kg-1 promoted a significant increase (**p<0.001 in the amount of gastric mucus. The data presented here demonstrated the potential gastroprotective activity from AqE, possibly attributed to the presence of flavonols in this extract. These results may serve as a support for the development of new treatments related to the pathology of gastric ulcer.Keywords: Gastric ulcer. Cytoprotection. Flavonoids. Bauhinia forficata.  

  13. Twin-tube practical acoustic thermometry: theory and measurements up to 1000 °C

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    Sutton, G.; Edwards, G.; Veltcheva, R.; de Podesta, M.

    2015-08-01

    We present details of a Practical Acoustic Thermometer (PAT), in which temperature is inferred from measurements of the speed of sound along acoustic waveguides. We describe both the theory of operation, and measurements on three devices at temperatures up to 1000 °C. Because the relationship between the speed of sound in a simple gas and absolute temperature is well understood, the mean temperature along a tube may be estimated from measurements of the frequency-dependent propagation constant. A PAT device made from two tubes of different lengths allows the temperature measurement region to be localised, creating an instrument functionally similar to conventional contact thermometers. Three twin-tube PAT devices were constructed and tested. PAT-A, made of silica, served to validate the technique with differences between the acoustic thermometer and a reference thermocouple of less than 2 °C at temperatures in the range from 100 °C to 1000 °C. PAT-B and PAT-C were made of Inconel-600, potentially more suitable for use in harsh environments. The Inconel devices deviated from expected behaviour in a reproducible manner, which after calibration allowed measurements with errors of less than  ±1 °C in the range to 700 °C. No drift was observed up to 700 °C. The drift observed during prolonged exposure to higher temperatures is described and its likely causes discussed. In the longer term, similar technology may provide a means for the measurement of temperature in harsh environments such as those found in the nuclear industry.

  14. Accumulation of Peptidoglycan O-Acetylation Leads to Altered Cell Wall Biochemistry and Negatively Impacts Pathogenesis Factors of Campylobacter jejuni*

    Science.gov (United States)

    Ha, Reuben; Frirdich, Emilisa; Sychantha, David; Biboy, Jacob; Taveirne, Michael E.; Johnson, Jeremiah G.; DiRita, Victor J.; Vollmer, Waldemar; Clarke, Anthony J.; Gaynor, Erin C.

    2016-01-01

    Campylobacter jejuni is a leading cause of bacterial gastroenteritis in the developed world. Despite its prevalence, its mechanisms of pathogenesis are poorly understood. Peptidoglycan (PG) is important for helical shape, colonization, and host-pathogen interactions in C. jejuni. Therefore, changes in PG greatly impact the physiology of this organism. O-acetylation of peptidoglycan (OAP) is a bacterial phenomenon proposed to be important for proper cell growth, characterized by acetylation of the C6 hydroxyl group of N-acetylmuramic acid in the PG glycan backbone. The OAP gene cluster consists of a PG O-acetyltransferase A (patA) for translocation of acetate into the periplasm, a PG O-acetyltransferase B (patB) for O-acetylation, and an O-acetylpeptidoglycan esterase (ape1) for de-O-acetylation. In this study, reduced OAP in ΔpatA and ΔpatB had minimal impact on C. jejuni growth and fitness under the conditions tested. However, accumulation of OAP in Δape1 resulted in marked differences in PG biochemistry, including O-acetylation, anhydromuropeptide levels, and changes not expected to result directly from Ape1 activity. This suggests that OAP may be a form of substrate level regulation in PG biosynthesis. Ape1 acetylesterase activity was confirmed in vitro using p-nitrophenyl acetate and O-acetylated PG as substrates. In addition, Δape1 exhibited defects in pathogenesis-associated phenotypes, including cell shape, motility, biofilm formation, cell surface hydrophobicity, and sodium deoxycholate sensitivity. Δape1 was also impaired for chick colonization and adhesion, invasion, intracellular survival, and induction of IL-8 production in INT407 cells in vitro. The importance of Ape1 in C. jejuni biology makes it a good candidate as an antimicrobial target. PMID:27474744

  15. Isolation of Sporothrix schenkii from the nails of healthy cats Isolamento de Sporothrix schenckii de unhas de gatos sadios

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    Lorena Leonardo de Souza

    2006-09-01

    Full Text Available Many cases of sporotrichosis in cats were diagnosed in the town of Rio Grande, RS, Brazil, caused mainly by inoculation due to scratches. In this work, we evaluated the frequency of Sporothrix schenckii in the nails of healthy cats living together with cats showing clinical sporotrichosis. The isolation of the fungus was carried out pressing unwashed nails of the forelimbs of 24 cats (48 paws directly onto the surface of Mycobiotic Agar in Petri dishes. S. schenckii was isolated from seven (29.1% cats. The procedure for isolation of the fungus was simpler than methods that require sedation and cuts of the nails.Um número elevado de casos de esporotricose em gatos foi diagnosticado na cidade de Rio Grande/RS/Brasil, e na maioria dos animais, a doença ocorreu após inoculação do fungo a partir de arranhões. Nesse estudo, avaliou-se a freqüência de Sporothrix schenckii nas unhas de gatos saudáveis que conviviam com gatos com esporotricose. O isolamento do fungo foi realizado a partir da impressão das unhas dos membros torácico direito e esquerdo, de 24 gatos (48 patas, diretamente em placas de Petri com Agar Mycobiotic sem lavagem prévia das unhas. S. schenckii foi isolado de sete gatos (29,1%. O procedimento adotado para o isolamento do fungo foi mais simples que os procedimentos que requerem sedação e corte das unhas do animal.

  16. Neonatal administration of fluoxetine did not alter the anxiety indicators, but decreased the locomotor activity in adult rats in the elevated plus-maze Administração neonatal de fluoxetina não alterou os indicadores de ansiedade, mas diminuiu a atividade locomotora em ratos adultos no labirinto elevado em cruz

    Directory of Open Access Journals (Sweden)

    Valdenilson Ribeiro Ribas

    2008-12-01

    Full Text Available The objective of this study was evaluate the anxiety and locomotor activity (LA in 52 Wistar adult male rats, being 26 treated with fluoxetine (10 mg/Kg - sc in the neonatal period. These same rats received foot shock (FS (1.6-mA - 2-s in the 90th day. The anxiety and LA were appraised by plus-maze. The time spent in the open arms was used as anxiety index and the LA was measured by number of entries in closed arms (NECA and the total of entries (TE. T-test was used with pO objetivo deste estudo foi avaliar a ansiedade e a atividade locomotora (AL em 52 ratos Wistar adultos machos, sendo 26 tratados no período neonatal com fluoxetina (10 mg/Kg - sc e no 90º dia, receberam estímulos elétricos nas patas (1,6-mA-2-s. A ansiedade e a AL foram avaliadas por meio do labirinto elevado em cruz. O tempo de permanência dos animais nos braços abertos (BA foi utilizado como índice de ansiedade e a AL medida pelo número de entradas nos braços fechados (NEBF e pelo total de entradas (TE nos BA e BF. O teste t foi utilizado, com (p<0,05 e os dados apresentados em média±erro padrão. Os animais tratados reduziram o NEBF (2,35±0,33 e o TE (3,96±0,61 comparados a seus controles (4,65±0,52 e (6,96±0,94. A administração neonatal de fluoxetina não alterou a ansiedade, mas diminuiu a AL dos animais que receberam EE.

  17. Relaciones entre morfología y forrajeo de artrópodos en colibríes de bosque altoandino

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    Rico Guevara Alejandra

    2006-06-01

    Full Text Available Con esta investigación se buscó reanudar el debate sobre la importancia que tiene el forrajeo de artrópodos en el estudio de la ecología y evolución de los colibríes. Se examinaron las tácticas de caza, preferencias en selección de presas, estructura morfológica y ciertos parámetros aerodinámicos de las especies encontradas en un bosque altoandino en los cerros orientales, como un primer acercamiento a las características de la depredación de artrópodos por colibríes en ambientes de alta montaña. Se tomaron las cuatro especies más abundantes en el área y se hicieron comparaciones entre tres fuentes de datos complementarias (comportamiento, dieta y morfología, para discutir las particularidades encontradas en este ensamblaje particular, con las tendencias e hipótesis anteriormente propuestas para bosque húmedo tropical. La comunidad de colibríes en conjunto, consumió muchas menos presas de superficie y más presas de aire en comparación con las especies de tierras bajas. Existen diferencias marcadas para el consumo de artrópodos entre las especies e incluso entre los sexos de cada especie, y éstas se relacionaron significativamente con algunas medidas relativas de ala, pico y patas, e índices aerodinámicos calculados para tales especies, sugiriendo la existencia de condicionamientos morfológicos, y por lo tanto presiones selectivas impuestas por la caza de artrópodos sobre el diseño corporal de los colibríes.

  18. Asociaciones implícitas como método para la detección de violencia y psicopatía.

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    Feggy Ostrosky-Solís

    2009-12-01

    Full Text Available La psicopatía es un trastorno de la personalidad que caracterizado por rasgos interpersonales, afectivos, conductuales y de estilo de vida. Está asociada con conducta violenta, existen pocos estudios que evalúen la tendencia hacia la violencia en psicópatas mediante técnicas de asociaciones implícitas como el Test de Asociaciones Implícitas (IAT. Se desarrolló el IAT-violencia, para evaluar las distorsiones cognitivas acerca de la violencia en 195 reos de acuerdo al nivel de psicopatía y al tipo de delito, se exploró el desempeño en la prueba de acuerdo a los niveles de los factores 1 y 2 de psicopatía. Los resultados indican que los sujetos violentos con alta psicopatía presentan distorsiones cognitivas acerca de la violencia. Aquellos con alto factor 2 de psicopatía presentan distorsiones cognitivas acerca de la violencia. Se discute la relación entre los factores 1 y 2 con la conducta violenta y la importancia de contar con instrumentos breves, confiables y objetivos. Las entrevistas semi-estructuradas requieren 1.5-3.5 horas, un entrenamiento especializado para evaluar el grado de psicopatía. Se discute el potencial para detectar sujetos que estén en riesgo de cometer alguna ofensa violenta mediante el IAT-violencia que toma 15 minutos y cuya calificación es automatizada.

  19. Problemas Del Pollo De Engorde Antes Y Después Del Beneficio (Pollo En Canal. 1º Parte

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    Sandra Lissette Ricaurte Galindo M.V.Z.

    2005-06-01

    Full Text Available Cuando los pollos llegan a la planta necesitan una ventilación adecuada en la zona de retención para minimizar la mortalidad y la pérdida excesiva de peso vivo. Los pollos que llegan deben ser programados para el procesamiento dentro de las 8 a 12 horas después de haber comido por última vez. De esta manera disminuye la cantidad de material que podría contaminar potencialmente la canal durante el procesamiento permitiendo tiempo suficiente para que el intestino se vacíe. Los pollos que quedan sin alimento por largos periodos (más de 13 a 14 horas comienzan a perder la mucosa intestinal y tendrán menor rendimiento en canal.Cuando se pierde la mucosa intestinal, el intestino resultante será mucho más débil y se romperá más fácilmente durante la evisceración, se procesa a los pollos principalmente para convertir sus músculos en carne, eliminar los componentes del cuerpo que no se desean (sangre, plumas, vísceras, patas y cabeza y mantener en un mínimo la contaminación microbiológica. La calidad del producto final depende no sólo de la condición de las aves cuando llegan a la planta, sino también de como se manejan durante el procesamiento. Lesiones, huesos rotos, partes faltantes y un número excesivo de reprocesamientos pueden ocasionar pérdidas económicas significativas. La descarga, aturdimiento, sacrificio, escaldado, desplumado, eviscerado, enfriamiento y empacado son algunas de las etapas del procesamiento que pueden ocasionar defectos en el producto. Así que estas etapas deben ser vigiladas.

  20. Fraccionamiento térmico de aceite de pollo

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    Grompone, María A.

    1994-12-01

    Full Text Available Properties of chicken oil industrially obtained in Uruguay are studied.
    Dry fractionation of neutralized and degummed chicken oil is carried out at laboratory employing two different temperature programmes. The oleine obtained at the final temperature of 13°C (yield of 79.2%, remains clear at 0°C during 20 minutes, and the one obtained at 9°C (yield of 76.3% during 240 minutes. The latter could be used as a substitute of neatsfoot oil.
    Melting points of stearines vary from 39.5°C to 41.5°C. Therefore, and given their composition, they could be used in food industry.

    Se estudian las propiedades del aceite de pollo obtenido industrialmente en el Uruguay.
    Se realizan, a nivel de laboratorio, fraccionamientos térmicos en seco de aceite de pollo neutralizado y desgomado, empleando dos programas de temperatura diferentes. La oleína obtenida a la temperatura final de 13°C (con un rendimiento del 79,2% permanece límpida a la temperatura de 0°C durante 20 minutos y la obtenida a 9°C (con un rendimiento del 76,3%, durante 240 minutos. Esta última podría ser utilizada como sustituto del aceite de patas de vacuno.
    Las estearinas obtenidas tienen puntos de fusión entre 39,5°C y 41,5°C. Por ello y por su composición podrían ser empleadas en productos alimenticios.

  1. El comportamiento animal como escudo para evitar la enfermedad y remedio hacia la salud (algunas bases fisiológicas

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    F. I. Flores

    2005-01-01

    Full Text Available Los animales viven en ambientes donde está presente, de manera permanente, la amenaza de enfermar. Para evitarlo, se alimentan lejos de las heces y reconocen las plantas o zonas del potrero que deben evitar. Aprenden, también, a ingerir especies o realizar conductas específicas con fines profilácticos. Si esto falla, entonces el animal manifiesta otras conductas y respuestas fisiológicas como: anorexia, inactividad, dolor y fiebre. El dolor obliga al animal a proteger el área dañada, evitando el apoyar una pata herida o inutilizando un músculo dañado, mientras los tejidos son reparados. La fiebre representa un alto costo energético, y para ahorrar energía, el animal tiende a permanecer inmóvil, estrategia de gran utilidad para controlar el crecimiento y reproducción de bacterias patógenas. En el comportamiento de los animales enfermos se han descubierto sustancias involucradas denominadas citocinas, que juegan un papel muy importante en la inducción de este tipo de conductas; por ejemplo, se puede inducir una disminución del consumo de alimento y en la actividad física inyectando sustancias provenientes de paredes celulares de bacterias o determinadas toxinas. El conocimiento de la conducta y sus bases fisiológicas en la lucha contra la enfermedad ofrecen expectativas prometedoras en la investigación para mejorar el diagnóstico y tratamiento de enfermedades

  2. DRD4 dopamine receptor allelic diversity in various primate species

    Energy Technology Data Exchange (ETDEWEB)

    Adamson, M.; Higley, D. [NIAAA, Rockville, MD (United States); O`Brien, S. [NCI, Frederick, MD (United States)] [and others

    1994-09-01

    The DRD4 dopamine receptor is uniquely characterized by a 48 bp repeating segment within the coding region, located in exon III. Different DRD4 alleles are produced by the presence of additional 48 bp repeats, each of which adds 16 amino acids to the length of the 3rd intracytoplasmic loop of the receptor. The DRD4 receptor is therefore an intriguing candidate gene for behaviors which are influenced by dopamine function. In several human populations, DRD4 alleles with 2-8 and 10 repeats have previously been identified, and the 4 and 7 repeat alleles are the most abundant. We have determined DRD4 genotypes in the following nonhuman primate species: chimpanzee N=2, pygmy chimpanzee N=2, gorilla N=4, siamang N=2, Gelada baboon N=1, gibbon N=1, orangutan (Bornean and Sumatran) N=62, spider monkey N=4, owl monkey N=1, Colobus monkey N=1, Patas monkey N=1, ruffed lemur N=1, rhesus macaque N=8, and vervet monkey N=28. The degree of DRD4 polymorphism and which DRD4 alleles were present both showed considerable variation across primate species. In contrast to the human, rhesus macaque monkeys were monomorphic. The 4 and 7 repeat allels, highly abundant in the human, may not be present in certain other primates. For example, the four spider monkeys we studied showed the 7, 8 and 9 repeat length alleles and the only gibbon we analyzed was homozygous for the 9 repeat allele (thus far not observed in the human). Genotyping of other primate species and sequencing of the individual DRD4 repeat alleles in different species may help us determine the ancestral DRD4 repeat length and identify connections between DRD4 genotype and phenotype.

  3. Holocene Charcoal Deposition From Brazilian Forest Fires

    Science.gov (United States)

    Turcq, B.; Cordeiro, R. C.; Albuquerque, A. S.; Simoes, F. L.; Sifeddine, A.

    2004-12-01

    Determination of charcoal accumulation rate in lacustrine sediments allows to reconstruct the fire history of the region surrounding the lake. Our studies have been achieved in three Amazonian sites and one site in Atlantic rainforest. Charcoal fragments are identified and counted under a microscope. Typical size of these charcoals is around ten micrometers and they probably have been subject to eolian transport. The highest charcoal accumulation rates were obtained in sediments from Middle Holocene in Carajás region, eastern Amazonia. These rates are on the same order than the present day charcoal accumulation rate in Alta Floresta, a region of Amazonia which is being submited to intense slash and burn. The lowest values were found in Lagoa da Pata in Sao Gabriel da Cachoeira, a very humid area in western Amazon. We observed from the D. Helvécio record, in the Atlantic rainforest, fire occurrences from 8,400 to 6,400 cal years BP. For Carajás lake, surrounded by tropical rain forest, we had identified fires during the period between 8,000 and 5,300 cal years BP. Finally, the lake Caracarana, which is surrounded by grass savanna, showed a record of main fire occurrence phase at 9,750 cal yrs BP and a second phase marked by charcoal peaks at 7,680, 6,990 and 6,460 cal yrs BP. The synchronism of the fire occurrence periods in different Brazilian regions is related to the Middle Holocene dry climate phase provoked by the low summer insolation. Differences in the accumulation rates can be attributed to differences in biomass availability and fire return time. The carbon released in the atmosphere by this fires must have contributed to the observed increase of CO2, poorer in 13C, during the middle Holocene.

  4. Isolation of poxvirus from debilitating cutaneous lesions on four immature grackles (Quiscalus sp.)

    Science.gov (United States)

    Docherty, D.E.; Long, R.I.R.; Flickinger, Edward L.; Locke, L.N.

    1991-01-01

    Poxvirus was isolated from nodules on four immature grackles (Quiscalus sp.) collected in two residential areas of Victoria, Texas. All of the birds were emaciated and had nodules on the eyelids, bill, legs, toes, and areas of the skin on the wings, neck, and ventral abdomen. These pox nodules were extensive and probably interfered with both sight and flight. The preliminary diagnosis was confirmed by virus isolation, histopathology, and electron microscopy. Poxvirus was isolated on the chorioallantoic membrane of embryonated hen's eggs and in Muscovy duck embryo fibroblast cell culture. Phaenicia calliphoridae (blowfly) larvae were found in one of the pox nodules, raising the possibility of mechanical transmission of the virus by contaminated adult blowfiles. /// Se aisl?? virus de viruela a partir de n??dulos presentes en cuatro estorninos inmaduros (Quiscalus sp.) capturados en dos ?!reas residenciales de Victoria, Texas. Las cuatro aves estaban emaciadas y presentaron n??dulos en los p?!rpados, pico, patas, dedos, y algunas ?!reas de la piel de las alas, cuello, y regi??n inferior del abdomen. Estos n??dulos producidos por viruela eran extensos y probablemente interfirieron con la visi??n y el vuelo. El diagn??stico presuntivo fue confirmado mediante aislamiento viral, histopatolog?-a, y microscop?-a electr??nica. Se aisl?? el virus de viruela en la membrana corioalantoidea de huevos embrionados de gallina y en cultivos celulares de fibroblasto de embri??n de pato. Se encontraron larvas de mosca azul (Phaenicia calliphoridae) en uno de los n??dulos de viruela, increment?!ndose as?- la posibilidad de transmisi??n mec?!nica del virus mediante moscas adultas contaminadas.

  5. Aislamiento y algunas propiedades de la toxina Be1 del veneno de Brachistosternus ehrenbergii (Gervais, 1841 (Scorpiones:Bothriuridae

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    Catherina Ramos

    2013-05-01

    Full Text Available Mediante cromatografía de intercambio catiónico en CM-Sephadex C-25 (16 x 1,1 cm con buffer acetato de amonio 0,05 M a pH 7, del veneno del escorpión Brachistosternus ehrenbergii fue aislada una proteína con acción tóxica sobre ratones albinos. En este sistema la toxina interactúa con el gel y es eluida al final luego de usar el mismo buffer conteniendo NaCl 0,6M. La toxina fue denominada Be1 y es una proteína básica que constituye el 8,1% de la proteína total del veneno. La pureza de la toxina fue evaluada por electroforesis en condiciones nativas, de acuerdo al método de Reisfeld, y en condiciones denaturantes por el método de Schägger y von Jagow, determinándose que la toxina es una sola cadena polipeptídica de 6,3 kDa. La inoculación de 60 μg de toxina en ratones albinos, vía intraperitoneal, genera la aparición de algunos signos locales como hipersecreción salival, seguido por afección respiratoria, arrastre de las patas posteriores, hasta finalmente al cabo de 2 horas, producir la muerte. Vía intramuscular (7,6 μg, Be1 produce parálisis temporal de la extremidad inoculada. La toxina no tiene actividades de fosfolipasa, proteasa, acetilcolinesterasa ni actividad inhibidora de acetilcolinesterasa.

  6. Metabolic encephalopathy and lipid storage myopathy associated with a presumptive mitochondrial fatty acid oxidation defect in a dog

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    Vanessa R Biegen

    2015-11-01

    Full Text Available A 1-year-old spayed female Shih Tzu presented for episodic abnormalities of posture and mentation. Neurologic examination was consistent with a bilaterally symmetric multifocal encephalopathy. The dog had a waxing-and-waning hyperlactemia and hypoglycemia. Magnetic resonance imaging revealed bilaterally symmetric cavitated lesions of the caudate nuclei with less severe abnormalities in the cerebellar nuclei. Empirical therapy was unsuccessful and the patient was euthanized. Post-mortem histopathology revealed bilaterally symmetric necrotic lesions of the caudate and cerebellar nuclei and multi-organ lipid accumulation, including a lipid storage myopathy. Malonic aciduria and ketonuria were found on urinary organic acid screen. Plasma acylcarnitine analysis suggested a fatty acid oxidation defect. Fatty acid oxidation disorders are inborn errors of metabolism documented in humans, but poorly described in dogs. Although neurologic signs have been described in humans with this group of diseases, descriptions of advanced imaging and histopathology are severely lacking. This report suggests that abnormalities of fatty acid metabolism may cause severe, bilateral gray matter necrosis and lipid accumulation in multiple organs including the skeletal muscles, liver, and kidneys. Veterinarians should be aware that fatty acid oxidation disorders, although potentially fatal, may be treatable. A timely definitive diagnosis is essential in guiding therapy.

  7. Long-term effects of manipulated natal brood size on metabolic rate in zebra finches.

    Science.gov (United States)

    Verhulst, Simon; Holveck, Marie-Jeanne; Riebel, Katharina

    2006-09-22

    Long-term effects of developmental conditions on health, longevity and other fitness components in humans are drawing increasing attention. In evolutionary ecology, such effects are of similar importance because of their role in the trade-off between quantity and quality of offspring. The central role of energy consumption is well documented for some long-term health effects in humans (e.g. obesity), but little is known of the long-term effects of rearing conditions on energy requirements later in life. We manipulated the rearing conditions in zebra finches (Taeniopygia guttata) using brood size manipulation and cross-fostering. It has previously been shown in this species that being reared in a large brood has negative fitness consequences, and that such effects are stronger in daughters than in sons. We show that, independent of mass, standard metabolic rate of 1-year-old birds was higher when they had been reared in a large brood, and this is to our knowledge the first demonstration of such an effect. Furthermore, the brood size effect was stronger in daughters than in sons. This suggests that metabolic efficiency may play a role in mediating the long-term fitness consequences of rearing conditions. PMID:17148435

  8. The effect of plant growth-promoting rhizobacteria on asparagus seedlings and germinating seeds subjected to water stress under greenhouse conditions.

    Science.gov (United States)

    Liddycoat, Scott M; Greenberg, Bruce M; Wolyn, David J

    2009-04-01

    Plant growth-promoting rhizobacteria (PGPR) can have positive effects on vigour and productivity, especially under stress conditions. In asparagus (Asparagus officinalis L.) field culture, seeds are planted in high-density nurseries, and 1-year-old crowns are transplanted to production fields. Performance can be negatively affected by water stress, transplant shock, and disease pressure on wounded roots. PGPR inoculation has the potential to alleviate some of the stresses incurred in the production system. In this study, the effects of PGPR (Pseudomonas spp.) treatment were determined on 3-week-old greenhouse-grown seedlings and germinating seeds of 2 asparagus cultivars. The pots were irrigated to a predetermined level that resulted in optimum growth or the plants were subjected to drought or flooding stress for 8 weeks. The cultivars responded differently to PGPR: single inoculations of seedlings enhanced growth of 'Guelph Millennium' under optimum conditions and 'Jersey Giant' seedlings under drought stress. Seed inoculations with PGPR resulted in a positive response only for 'Guelph Millennium', for which both single or multiple inoculations enhanced plant growth under drought stress.

  9. Bordetella pertussis.

    Science.gov (United States)

    Nieves, Delma J; Heininger, Ulrich

    2016-06-01

    Pertussis is a highly infectious vaccine-preventable cough illness that continues to be a significant source of morbidity and mortality around the world. The majority of human illness is caused by Bordetella pertussis, and some is caused by Bordetella parapertussis. Bordetella is a Gram-negative, pleomorphic, aerobic coccobacillus. In the past several years, even countries with high immunization rates in early childhood have experienced rises in pertussis cases. Reasons for the resurgence of reported pertussis may include molecular changes in the organism and increased awareness and diagnostic capabilities, as well as lessened vaccine efficacy and waning immunity. The most morbidity and mortality with pertussis infection is seen in infants too young to benefit from immunization. Severe infection requiring hospitalization, including in an intensive care setting, is mostly seen in those under 3 months of age. As a result, research and public health actions have been aimed at better understanding and reducing the spread of Bordetella pertussis. Studies comparing the cost benefit of cocooning strategies versus immunization of pregnant women have been favorable towards immunizing pregnant women. This strategy is expected to prevent a larger number of pertussis cases, hospitalizations, and deaths in infants <1 year old while also being cost-effective. Studies have demonstrated that the source of infection in infants usually is a family member. Efforts to immunize children and adults, in particular pregnant women, need to remain strong.

  10. Low skin conductance activity in infancy predicts aggression in toddlers 2 years later.

    Science.gov (United States)

    Baker, Erika; Shelton, Katherine H; Baibazarova, Eugenia; Hay, Dale F; van Goozen, Stephanie H M

    2013-06-01

    Low autonomic nervous system activity is claimed to be a biomarker for aggressive and antisocial behavior. Although there is evidence that low skin conductance activity (SCA) accounts for variation in the severity of antisocial behavior and predicts the onset of aggression in children and adults, it is unknown whether SCA measured in infancy can predict the development of aggression. We measured SCA in 70 typically developing 1-year-old infants at baseline, during an orienting habituation paradigm, and during a fear challenge. We also observed the infants' fear behavior, and each mother rated her infant's temperament and her attachment to her child. At follow-up, mothers rated the children at 3 years old for aggressive and nonaggressive behavior problems. Low infant SCA predicted aggressive behavior, but there was no association between SCA and nonaggressive behavior problems. Mothers' ratings of the infants' temperament and their maternal attachment and the infants' observed fearlessness did not predict later aggression. These results suggest that SCA is a specific biomarker for aggression in low-risk samples of infants.

  11. Electrocardiographic Indices in Clinically Healthy Iranian Najdi Goats in Different Ages: A Reference Study

    Directory of Open Access Journals (Sweden)

    Aliasghar CHALMEH

    2015-07-01

    Full Text Available The cardiovascular system develops along with growing the animals. Information regarding the alterations of electrocardiographic parameters during aging can provide the basis to evaluate the development of cardiovascular system. Hence, the present study was performed to clarify the effect of aging on electrocardiographic alterations in Iranian Najdi goats. The electrocardiograms were recorded on a bipolar base apex lead from 172 clinically healthy Iranian Najdi does into 9 age groups, including 15-day-old (n=18, 2 (n=18, 6 (n=19, 9-month-old (n=21, 1 (n=20, 2 (n=22, 3 (n=19, 5 (n=18 and 7-year-old (n=17. All electrocardiograms were examined to evaluate normal electrocardiographic parameters and cardiac arrhythmias. Finally changing of the electrocardiographic parameters during aging was statistically determined. P, S and T durations were increased significantly during aging. Furthermore, the significant increases were seen in RR, QT and ST intervals. Sinus tachycardia and sinus arrhythmia were the most common cardiac arrhythmias in studied animals. The proportion of cardiac arrhythmias in under 1-year-old kids was significantly higher than other groups. It may be concluded that aging can affect electrocardiographic parameters in Iranian Najdi goats.

  12. Metacognición, escritura y rendimiento académico en universitarios de Colombia y Francia

    Directory of Open Access Journals (Sweden)

    Kiara Campo

    2016-04-01

    Full Text Available The main of this article were: (1 To describe the degree of objectives knowledge and the planning strategies identified by university students in relation to the process of developing written texts, and (2 to establish the link between the students’ perception about these processes and the academic success. The hypothesis was that the students that describe a low degree of metacognitive knowledge and planning strategies used in the process of writing, show low levels of academic success. A comparative and descriptive research design was used with 462 students selected intentionally from two psychology programs (231 Colombian and 231 French students with average age of 18.8 and 20.1 years old respectively. These students completed a questionnaire composed by two scales: Metacognitive Knowledge and Planning Strategies in Writing. It was found that the students acknowledged their metacognitive knowledge used when developing their written texts. The Colombian students described that they use planning strategies occasionally while the French students declared that they use this strategy more frequently. In addition, a positive correlation appeared between the metacognition and the academic success.

  13. Estudio retrospectivo de las enfermedades respiratorias en felinos diagnosticadas clínicamente en el Hospital Veterinario de la Universidad Austral de Chile, Valdivia, durante el período 1997-2004 A retrospective study on feline respiratory diseases clinically diagnosed at the Universidad Austral de Chile Veterinary Hospital, Valdivia, between 1997 and 2004

    Directory of Open Access Journals (Sweden)

    L Azócar

    2008-01-01

    Veterinary Hospital at the Universidad Austral de Chile between 1997 and 2004, were analyzed. A total of 2,068 clinical records were examined, of which 291 were identified as respiratory diseases. Most cases were observed in male felines of less than 1 year-old (53.8%, from 1 to 5.9 year-old (57.8%, and among female felines of 6 years of age and older (64.7%. The most affected topographic area was the upper respiratory tract (57.1%, most likely to occur in felines of less than 1 year-old (58.5%. Feline Respiratory Syndrome was the most frequent diagnosis (128 cases with a high rate of cases in male felines of less than 1 year-old (56.4%, from 1 and 5.9 year-old (54.3% and among felines of 6 years of age and older (75.0%. The frequency of respiratory diseases increased during August (13.7%. Feline Respiratory Syndrome had more cases during March (11.7% and September (12.5%. The respiratory disease endemic index during the study period showed an epidemic curve in March, April, May, July, November and December of 2002. Regarding Feline Respiratory Syndrome, there was an epidemic curve in March, April, June, July, November and December of 2002. It was concluded that respiratory diseases affected more frequently male felines of less than 1 year-old; being the upper respiratory tract the most affected area; Feline Respiratory Syndrome was the most frequent diagnosis and the frequency of feline respiratory diseases varied according to month of the year.

  14. Radiation contamination after the Chernobyl nuclear accident and the effective dose received by the population of Croatia

    International Nuclear Information System (INIS)

    Because of the Chernobyl nuclear accident which led to enhanced deposition of all fission products, contamination of the human environment in the Republic of Croatia was much higher than in the previous two decades. The paper deals with the investigation of deposition and contamination by fission product radionuclides (137Cs and 90Sr, in particular), especially within the human food chain. Its aim was to determine differences in contamination levels resulting from the Chernobyl accident and from large-scale atmospheric nuclear weapon tests. For the year following the Chernobyl accident, the radiation doses received from external and internal exposures were estimated for 1-year old infants, children at the age of 10-years and adults. The corresponding annual effective doses were 1·49, 0·93 and 0·83 mSv, respectively. The paper also gives data on the yearly intakes of 137Cs and 90Sr in foods and the corresponding effective doses received by the population of Croatia over many years from the global fallout following nuclear weapons testing and the Chernobyl accident. (Copyright (c) 1998 Elsevier Science B.V., Amsterdam. All rights reserved.)

  15. Exposure to BPA in Children—Media-Based and Biomonitoring-Based Approaches

    Directory of Open Access Journals (Sweden)

    Krista L.Y. Christensen

    2014-04-01

    Full Text Available Bisphenol A (BPA is used in numerous industrial and consumer product applications resulting in ubiquitous exposure. Children’s exposure is of particular concern because of evidence of developmental effects. Childhood exposure is estimated for different age groups in two ways. The “forward” approach uses information on BPA concentrations in food and other environmental media (air, water, etc. combined with average contact rates for each medium. The “backward” approach relies on urinary biomonitoring, extrapolating backward to the intake which would have led to the observed biomarker level. The forward analysis shows that BPA intakes are dominated by canned food consumption, and that intakes are higher for younger ages. Mean intake estimates ranged from ~125 ng/kg-day for 1 year-olds to ~73 ng/kg-day among 16–20 years olds. Biomonitoring-based intakes show the same trend of lower intakes for older children, with an estimate of 121 (median to 153 (mean ng/kg-day for 2–6 years, compared with 33 (median to 53–66 (mean ng/kg-day for 16–20 years. Infant intakes were estimated to range from ~46 to 137 ng/kg-day. Recognizing uncertainties and limitations, this analysis suggests that the “forward” and “backward” methods provide comparable results and identify canned foods as a potentially important source of BPA exposure for children.

  16. A study (1977-1992) of population dynamics of endoparasites featuring benzimidazole-resistant small strongyles (population S) in Shetland ponies.

    Science.gov (United States)

    Lyons, E T; Tolliver, S C; Drudge, J H; Stamper, S; Swerczek, T W; Granstrom, D E

    1996-11-01

    Critical tests (91) were done between 1977 and 1992 in Shetland ponies to evaluate drug susceptibility and population dynamics (present paper) of endoparasites. The test ponies, most less than 1 year old, were from a herd where older animals were treated every 8 weeks initially with cambendazole (CBZ) (1974-1978) and then with oxibendazole (OBZ) (1978-1992). Previous field test data (1974-1992) on older ponies in the breeding herd indicated the presence of benzimidazole (BZ) resistant small strongyles. Data on population dynamics from the present critical tests indicated that 28 species of small strongyles persisted over the study period in spite of initial susceptibility and later refractiveness of six species to both CBZ and OBZ. Changes in intensities and other aspects were observed for the six BZ-resistant species (Cyathostomum catinatium, Cyathostomum coronatum, Cylicocyclus nassatus, Cylicostephanus calicatus, Cylicostephanus goldi, and Cylicostephanus longibursatus). Variabilities, some striking, were found in prevalence and intensity in bots, stomach worms, ascarids, eyeworms, large strongyles, pinworms and tapeworms.

  17. Influence of Soil Compaction and Drought on the Growth,Photosynthesis and Carbohydrates in Fugi/M.9EMLA Apple Plants

    Institute of Scientific and Technical Information of China (English)

    YAO Yun-cong; John G Streeter; David C Ferree

    2003-01-01

    Greenhouse-grown 1-year-old potted M.9EMLA apple trees (Malus pumila Borkh) were subjected to the soil compaction and, after growing under compacted or non-compacted conditions for 6 weeks, were subjected to drought stress by withholding water for an additional six-week period. Soil compaction and drought stress significantly reduced plant height, number of leaves, and leaf area. Although drought significantly inhibited photosynthesis and transpiration, compaction only depressed transpiration. Furthermore, the effects of drought on plant growth, photosynthesis and transpiration were much greater than the effects of compaction. The rate of water loss from compacted plants was lower than the rate from non-compacted controls and this may explain the insignificant impact of compaction on photosynthesis. Sorbitol, glucose, and fructose concentrations increased over time during the drought stress period whereas sucrose concentration declined. In well-watered controls, sucrose concentration was much higher in leaves of compacted plants than in the leaves on non-compacted controls. For most of the sampling dates the leaf sorbitol concentration was lower in leaves on plants growing in compacted soil than in the leaves of those of the non-compacted controls. Although interactions between the effects of compaction and drought were highly significant for plant growth variables during the onset of drought, interactive effects on photosynthesis, transpiration, relative water content and carbohydrate variables were inconsistent. Compaction and drought both have major effects on apple plants and the interactions between these two stresses are complex.

  18. Animal-Assisted Activities: Results From a Survey of Top-Ranked Pediatric Oncology Hospitals.

    Science.gov (United States)

    Chubak, Jessica; Hawkes, Rene

    2016-07-01

    Animal-assisted activities (AAA) are increasingly common, yet little is known about practices in pediatric oncology. To address this gap, we surveyed the top 20 pediatric oncology hospitals in the United States in May and June of 2014. Questionnaires were sent via e-mail and generally returned by e-mail or postal mail. Among the 19 responding hospitals, the 18 that offered AAA to pediatric patients formed the basis of our analysis. All sites had written AAA policies. Most programs were restricted to dogs. At 11 hospitals, children with cancer could participate in AAA activities. Outpatient waiting rooms and individual inpatient rooms were the most common locations for AAA with pediatric oncology patients. Safety precautions varied by hospital, but all required hand sanitation after visits and that animals receive an annual health examination, be on a leash or in a carrier, be ≥1 year old, and not be directly from a shelter. Our findings reveal consistencies and variations in practice that may help other hospitals develop their own programs and researchers identify areas of future study.

  19. The Patagonian toothfish: biology, ecology and fishery.

    Science.gov (United States)

    Collins, Martin A; Brickle, Paul; Brown, Judith; Belchier, Mark

    2010-01-01

    Patagonian toothfish (Dissostichus eleginoides) is a large notothenioid fish that supports valuable fisheries throughout the Southern Ocean. D. eleginoides are found on the southern shelves and slopes of South America and around the sub-Antarctic islands of the Southern Ocean. Patagonian toothfish are a long-lived species (>50 years), which initially grow rapidly on the shallow shelf areas, before undertaking an ontogenetic migration into deeper water. Although they are active predators and scavengers, there is no evidence of large-scale geographic migrations, and studies using genetics, biochemistry, parasite fauna and tagging indicate a high degree of isolation between populations in the Indian Ocean, South Georgia and the Patagonian Shelf. Patagonian toothfish spawn in deep water (ca. 1000 m) during the austral winter, producing pelagic eggs and larvae. Larvae switch to a demersal habitat at around 100 mm (1-year-old) and inhabit relatively shallow water (illegal, unreported and unregulated fishing (IUU). These problems have now largely been addressed, but continued vigilance is required to ensure that the species is sustainably exploited and the ecosystem effects of the fisheries are minimised.

  20. Mucosubstance histochemistry in control and acid-stressed epidermis of brown bullhead catfish, Ictalurus nebulosus (LeSueur)

    International Nuclear Information System (INIS)

    Glycoprotein components of epidermal mucous cells in control (pH 6.8) and acid-stressed (pH 5.8, 4.8, 4.0) brown bullhead catfish were studied by histochemical and autoradiographic methods. Following exposure to acid, increased numbers of epidermal mucous cells were noted in all tissue sites studied, particularly dorsal and ventral skin. Mucous cells of control fish and acid-stressed (pH 5.8) fish contained a mixture of neutral and acidic mucosubstances, the latter including both sialomucins and sulfomucins, with sialomucins predominating. An apparent shift toward increased sulfomucin production was observed in skin from fish exposed to pH 4.8 and 4.0. In addition, autoradiographic studies using 35S showed increased labeling of mucous cells in acid-exposed (pH 4.0) epidermis, offering further support for a shift toward sulfomucin production in acid-stressed fish. Absence of appreciable sulfomucin production in younger fish (less than 1 year old) suggested that this shift may be partly age-dependent. The functional significance of increased sulfomucin production in acid-stressed epidermal mucous cells is uncertain but may be related to maintenance of ionic equilibrium

  1. Epidemiological characteristics of varicella from 2000 to 2008 and the impact of nationwide immunization in Taiwan

    Directory of Open Access Journals (Sweden)

    Chang Luan-Yin

    2011-12-01

    Full Text Available Abstract Background Varicella has an important impact on public health. Starting in 2004 in Taiwan, nationwide free varicella vaccinations were given to 1-year-old children. Methods Our study investigated the epidemiological characteristics of varicella from 2000 to 2008, and assessed the change of varicella epidemiology after the mass varicella immunization. ICD-9-CM codes related to varicella or chickenpox (052, 052.1, 052.2, 052.7, 052.8, 052.9 were analyzed for all young people under 20 years of age through the National Health Insurance database of Taiwan from 2000 to 2008. Results Case numbers of varicella or chickenpox significantly declined after the nationwide immunization in 2004. Winter, particularly January, was the epidemic season of varicella. We found a significant post-vaccination decrease in incidence among preschool children, especially 3 to 6 year-old children-- the peak incidence was 66 per thousand for 4 and 5 year-old children before the nationwide immunization (2000 to 2003, and the peak incidence was 23 per thousand for 6 year-old children in 2008 (p Conclusion The varicella annual incidence and varicella-related hospitalization markedly declined in preschool children after nationwide varicella immunization in 2004.

  2. Cold hardiness of interspecific hybrids between Pinus strobus and P. wallichiana measured by post-freezing needle electrolyte leakage.

    Science.gov (United States)

    Lu, Pengxin; Colombo, Stephen J; Sinclair, Robert W

    2007-02-01

    Interspecific hybrids between eastern white pine (Pinus strobus L.) and Himalayan blue pine (P. wallichiana A. B. Jacks.) were developed in Ontario, Canada, to introduce blister rust (Cronartium ribicola Fisch.) resistance genes to P. strobus. There is concern that introducing blister rust resistance has resulted in reduced cold hardiness of the progeny compared with non-hybridized eastern white pine. To test the efficacy of backcrossing with P. strobus to improve cold hardiness, 1-year-old seedlings from hybrid crosses differing in P. strobus genome composition were artificially freeze-tested. In Experiment 1, unhardened seedlings were allowed to acclimate to progressively lower temperatures in a growth room, whereas in Experiment 2, seedlings were hardened outdoors under natural weather conditions in Sault Ste Marie, Ontario. Needle cold injury was determined by calculating relative electrical conductivity based on post-freezing electrolyte leakage. Results indicated that needle fascicles from unhardened seedlings of all genotypes in the greenhouse tolerated -5 degrees C for 3 hours with little or no injury. Cold hardiness increased in parallel with declining growth room minimum temperature over the 7-week period of hardening. Cold hardiness was improved for hybrid crosses with increased Pinus strobus genome composition in Experiment 2, but the results were less conclusive in Experiment 1. PMID:17241966

  3. Impact of Gender in Renal Cell Carcinoma: The Relationship of FABP7 and BRN2 Expression with Overall Survival

    Science.gov (United States)

    Tan, Cheng; Takayama, Tatsuya; Takaoka, Naohisa; Fujita, Hiromi; Miyazaki, Miki; Sugiyama, Takayuki; Ozono, Seiichiro

    2014-01-01

    OBJECTIVE To investigate the relationship between gender differences in fatty acid-binding protein7 (FABP7) and BRN2 (POU class 3 homeobox 2) expression in renal cell carcinoma (RCC) and the prognosis of patients with RCC. MATERIALS AND METHODS immunohistochemical (IHC) staining as well as reverse transcription-polymerase chain reaction (RT-PCR) was performed in renal tissues from 103 patients (83 men, mean age = 63.6 years old; 20 women, mean age = 63.1 years old) underwent radical nephrectomy from January 1, 2001 through December 31, 2010. The probability of overall patient survival was estimated using the Kaplan-Meier method. RESULTS FABP7 mRNA expression was more frequent in men (P = 0.07) while BRN2 protein expression was significantly more frequent in women (P = 0.029). In particular, FABP7 was expressed in 100% of G1 renal cell carcinoma both in mRNA and protein levels. In women, FABP7 (−) and BRN2 (+) groups had a worse prognosis both in mRNA level (P = 0.038) and protein level (P = 0.058). BRN2 was expressed 100% of papillary RCC both in mRNA and protein levels. CONCLUSIONS Our results demonstrated that gender was a key factor in FABP7 and BRN2 expression in RCC, and the combination with FABP7 and BRN2 stratified by gender could be a new potential prognostic factor in patients with RCC. PMID:24653654

  4. Determination of essential elements in commercial infant foods by instrumental neutron activation analysis

    International Nuclear Information System (INIS)

    Eating habits are important determinants of health conditions during childhood. Commercial infant food is an important part of the diet for many babies. As such it is necessary that such food contain sufficient amounts of essential elements. Inadequate complementary feeding is a major cause of high rates of malnutrition throughout the world. Commercial infant food is classified into four different stages: Stages 1 and 2 are adequate for babies older than 6 months, but new flavors and food are introduced in stage 2; Stage 3 is offered to 8 month old babies; Junior Stage is recommended to children over 1 year old. In this study, essential elements: Ca, Cl, Co, Cr, Fe K, Mg, Mn, Na, Se and Zn were determined in commercial infant food samples by Instrumental Neutron Activation Analysis (INAA). Twenty-seven infant food samples were bought in stores around Sao Paulo city during 2011. These samples were freeze-dried and homogenized before analysis. The powdered samples were irradiated in the IEA-R1 nuclear research reactor of IPEN-CNEN/SP. For validation of the methodology, INCT MPH-2 Mixed Polish Herbs and NIST-SRM 1577b Bovine Liver reference materials were analyzed. Most of the concentration results were below the World Health Organization's recommended daily intake for infants from 6 to 12 months old. These low essential element concentration results in commercial infant foods obtained in our study indicate that infants should not only be fed with commercial baby foods. (author)

  5. Ketamine and midazolam sedation for pediatric gastroinntestinal endoscopy in the Arab world

    Institute of Scientific and Technical Information of China (English)

    Mohamad-Iqbal S Miqdady; Wail A Hayajneh; Ruba Abdelhadi; Mark A Gilger

    2011-01-01

    AIM: To evaluate the safety and effectiveness of intravenous ketamine-midazolam sedation during pediatric endoscopy in the Arab world. METHODS: A retrospective cohort study of all pediatric endoscopic procedures performed between 2002-2008 at the shared endoscopy suite of King Abdullah University Hospital, Jordan University of Science & Technology, Jordan was conducted. All children were > 1 year old and weighed > 10 kg with American Society of Anesthesiologists class 1 or 2. Analysis was performed in terms of sedation-related complications (desaturation, respiratory distress, apnea, bradycardia, cardiac arrest, emergence reactions), adequacy of sedation, need for sedation reversal, or failure to complete the procedure. RESULTS: A total of 301 patients (including 160 males) with a mean age of 9.26 years (range, 1-18 years) were included. All were premedicated with atropine; and 79.4% (239/301) had effective and uneventful sedation. And 248 (82.4%) of the 301 patients received a mean dose of 0.16 mg/kg (range, 0.07-0.39) midazolam and 1.06 mg/kg (range, 0.31-2.67) ketamine, respectively within the recommended dosage guidelines. Recommended maximum midazolam dose was exceeded in 17.6% patients [34 female (F):19 male (M), P = 0.003] and ketamine in 2.7% (3 M:5 F). Maximum midazolam dose was more likely to be exceeded than ketamine (P 1 year and weighing > 10 kg without co-morbidities.

  6. Long working distance optical coherence tomography for pediatric imaging (Conference Presentation)

    Science.gov (United States)

    Qian, Ruobing; Carrasco-Zevallos, Oscar; Vajzovic, Lejla; Gramatikov, Boris I.; Guyton, David L.; Toth, Cynthia A.; Izatt, Joseph A.

    2016-03-01

    Conventional optical coherence tomography (OCT) systems have working distances of about 25 mm, and require cooperative subjects to immobilize and fixate on a target. Handheld OCT probes have also been demonstrated for successful imaging of pre-term infants and neonates up to ~1 year old. However, no technology yet exists for OCT in young children due to their lack of attention and inherent fear of large objects close to their face. In this work, we demonstrate a prototype retinal swept-source OCT system with a long working distance (from the last optical element to the subject's eye) to facilitate pediatric imaging. To reduce the footprint and weight of the system compared to the conventional 4f scheme, a novel 2f scanning configuration was implemented to achieve a working distance of 348mm with a +/- 8° scanning angle prior to cornea. Employing two custom-designed lenses, the system design resolution was nearly diffraction limited throughout a -8D to +5D refractive corrections. A fixation target displayed on a LCD monitor and an iris camera were used to facilitate alignment and imaging. Our prototype was tested in consented adult subjects and has the potential to facilitate imaging of young children. With this apparatus, young children could potentially sit comfortably in caretaker's lap while viewing entertainment on the fixation screen designed to direct their gaze into the imaging apparatus.

  7. COEXISTENCE OF CUTANEOUS MUCORMYCOSIS AND SCROFULODERMA IN AN IMMUNODEFICIENT CHILD

    Directory of Open Access Journals (Sweden)

    Mahalakshmi

    2016-01-01

    Full Text Available Severe Combined Immunodeficiency (SCID is a genetic disorder characterised by the disturbed development of functional T cells and B cells caused by numerous genetic mutations. (1 These patients are extremely vulnerable to infectious diseases and early death. (1 A 1-year-old child, known case of SCID since 8 months of age, presented with septic shock. He had a swelling on the left hand for 1 month and over left hand, which was a prior site of IV cannulation and swelling over axilla since 6 months. The child received multiple blood transfusions, though no bone marrow transplant was done. We entertained a differential diagnosis of cutaneous tuberculosis, atypical mycobacterial infection, deep fungal infection and foreign body granuloma for the left hand nodule. We thought of scrofuloderma with lymphadenopathy as a diagnosis for the axillary lesion. Biopsy of the hand lesion-multiple broad aseptate hyphae with granulomatous infiltrates suggesting mucormycosis. FNAC of axillary lymph node-necrotising lymphadenitis with AFB positive. Chest X-ray HRCT-PCP Pneumonia. He was started on IV Amphotericin-B

  8. Free-ranging macaque mothers exaggerate tool-using behavior when observed by offspring.

    Directory of Open Access Journals (Sweden)

    Nobuo Masataka

    Full Text Available The population-level use of tools has been reported in various animals. Nonetheless, how tool use might spread throughout a population is still an open question. In order to answer that, we observed the behavior of inserting human hair or human-hair-like material between their teeth as if they were using dental floss in a group of long-tailed macaques (Macaca fascicularis in Thailand. The observation was undertaken by video-recording the tool-use of 7 adult females who were rearing 1-year-old infants, using the focal-animal-sampling method. When the data recorded were analyzed separately according to the presence/absence of the infant of the target animal in the target animal's proximity, the pattern of the tool-using action of long-tailed adult female macaques under our observation changed in the presence of the infant as compared with that in the absence of the infant so that the stream of tool-using action was punctuated by more pauses, repeated more often, and performed for a longer period during each bout in the presence of the infant. We interpret this as evidence for the possibility that they exaggerate their action in tool-using so as to facilitate the learning of the action by their own infants.

  9. Differential expression of zinc accumulation during two growing seasons of Acacia victoriae

    Institute of Scientific and Technical Information of China (English)

    Ali Mahdavi; Khadijeh Khermandar

    2015-01-01

    It is important to understand seasonal heavy metal accumulation in different parts of plants in order to develop the best phytoremediation practices for con-taminated soils. For this purpose we exposed, 1 year old A. victoriae seedlings to ZnSO4 in 4 different concentrations:0, 50, 250 and 500 mg Zn L-1 for 45 days over two growing seasons. Subsequently, bioaccumulation of Zn in different plant tissues (roots, shoots and leafs) was assessed by Atomic Absorption Spectroscopy (AAS) for two peri-ods. In addition, various growth attributes (dry biomass, shoot and root lengths, plant appearance) and functional traits (leaf area, chlorophyll a, b and total) were measured. The accumulation of Zn was influenced by the Zn con-centration in the growth medium and the number of growing seasons. The amounts of Zn concentrated in the root tissues might indicate A. victoriae as a good option for phytostabilization of soils contaminated by Zn. We rec-ommend that if A. victoriae is used for phytoextraction purposes, then it should be harvested at the end of the first growing season (fall) because at this time the concentra-tions of Zn in the above-ground parts will be maximal.

  10. Clinical variability in neurohepatic syndrome due to combined mitochondrial DNA depletion and Gaucher disease

    Directory of Open Access Journals (Sweden)

    Julie Harvengt

    2014-01-01

    Full Text Available A 1-year-old girl born to consanguineous parents presented with unexplained liver failure, leading to transplantation at 19 months. Subsequent partial splenectomy for persistent cytopenia showed the presence of foamy cells, and Gaucher disease was confirmed by homozygosity for the p.Leu483Pro mutation in the GBA gene. She was treated by enzyme replacement therapy (ERT. Clinical follow-up showed mild developmental delay, strabismus, nystagmus and oculomotor apraxia. Biochemical studies revealed multiple respiratory chain deficiencies and a mosaic pattern of deficient complex IV immunostaining in liver and fibroblast. Molecular analysis identified a mtDNA depletion syndrome due to the homozygous p.Pro98Leu mutation in MPV17. A younger sister unaffected by mtDNA depletion, presented with pancytopenia and hepatosplenomegaly. ERT for Gaucher disease resulted in visceral normalization without any neurological symptom. A third sister, affected by both conditions, had marked developmental delay, strabismus and ophthalmoplegia but no liver cirrhosis. In conclusion, intrafamilal variability occurs in MPV17-related disease. The combined pathological effect of Gaucher and mitochondrial diseases can negatively impact neurological and liver functions and influence the outcome in consanguineous families. The immunocytochemical staining of OXPHOS protein in tissues and cultured cells is a powerful tool revealing mosaic pattern of deficiency pointing to mtDNA-related mitochondrial disorders.

  11. Trends in Oral Antibiotic, Proton Pump Inhibitor, and Histamine 2 Receptor Blocker Prescription Patterns for Children Compared With Adults: Implications for Clostridium difficile Infection in the Community.

    Science.gov (United States)

    Faden, Howard S; Ma, Chan-Xing

    2016-07-01

    The use of antibiotics, proton pump inhibitor (PPI), and histamine 2 receptor blocker (H2B) was compared between children and adults in the community from 2005 through 2011. Antibiotic prescription rates remained stable for children, but increased significantly for adults, P = .03. PPI prescription rates increased for children, P = .02 and for adults, P = .009. H2B prescription rates increased for children, P = .03, but not for adults. Antibiotic prescription rates were significantly higher in children than adults in all 7 years, P < .0001. In contrast, PPI prescription rates were significantly higher in adults than children in all 7 years, P < .0001. H2B prescription rates were significantly higher in adults than children 1 to 18 years old P < .0001; however, H2B prescription rates were highest in children <1 year old, P = .0001. The high use of oral antibiotics, PPI, and H2B among outpatients may be a contributing factor to the rise of Clostridium difficile infection in the community. PMID:26350427

  12. Incidence of Acute Diarrhea Among Children Aged 0 - 1 Year in Southern Brazil, 2012

    Directory of Open Access Journals (Sweden)

    Nascimento

    2015-09-01

    Full Text Available Background The incidence rate of acute diarrheal disease in children is a health indicator, and the estimation of these data can help guide public health policies. Objectives The aim of this study was to estimate the incidence and risk factors for acute diarrheal disease in children aged 0 - 1 year. Patients and Methods An observational prospective cohort study was conducted on 210 children recruited at Hospital Nossa Senhora da Conceicao, in Tubarao, state of Santa Catarina, Brazil. Children born between July and September 2012 were followed up for 12 months. The presence of three or more liquid or loose stools during a 24-hour period was considered acute diarrhea. The categories of variables evaluated were comprised of sociodemographic characteristics (per capita income, maternal education, maternal age, access to medical care [public or private], and housing and living conditions [sanitation and hygiene, water supply, daycare attendance, and domestic animal] and characteristics of the child (gender, birth weight, and breastfeeding. Results The incidence of acute diarrhea among the 0 - 1-year-old children was 26.7 cases per 1,000 children per month. Independent risk factors for the occurrence of diarrhea were maternal age under 20 years and health care services provided by the Brazilian National Health System (SUS. Conclusions The high incidence density of diarrhea among the children recruited in this study indicates the need for educational programs directed at people who are involved in this issue.

  13. Development of the gonads in the triploid (ZZW and ZZZ) fowl, Gallus domesticus, and comparison with normal diploid males (ZZ) and females (ZW).

    Science.gov (United States)

    Lin, M; Thorne, M H; Martin, I C; Sheldon, B L; Jones, R C

    1995-01-01

    Gonadal development in fowls aged from 1 day to more than 4.5 years was studied in 63 ZZW and 16 ZZZ triploid crossbreds and compared with normal diploid males (ZZ) and females (ZW). In the ZZW fowl, the right gonad developed into a testis (although this occurred earlier in the ZZ genotype), and a structurally-abnormal excurrent duct system containing some malformed spermatids and spermatozoa was associated with the gonad of young adults. The left gonad was an ovotestes at hatching and no excurrent ducts were associated with it. The ovarian component was much less developed than that in the ZW genotype-it started to degenerate by 1 week of age, and most of the oocytes had disappeared by about 3 weeks of age. The seminiferous tubules developed in the medullary region, but only abnormal spermatozoa were produced. Leukocytes infiltrated both gonads at about 9 months of age and the seminiferous epithelium had degenerated in most fowls over 1 year old. In ZZZ fowl, gonadal and excurrent duct development was normal, but occurred earlier than in the ZZ genotype. However, meiosis and spermiogenesis were abnormal and malformed spermatozoa were produced. The heads of spermatozoa from the ducts deferens were about 1.4-times longer in the ZZZ genotype than in the ZZ genotype, indicating that the former may be producing some diploid spermatozoa. PMID:8848586

  14. [Infanticide. Social and forensic aspects].

    Science.gov (United States)

    Bätje, C; Schläfke, D; Nedopil, N; Hässler, F

    2011-07-01

    Infanticides are not specifically classified in German criminal records. Thus, the number of infanticides varies depending on different sources of information. Reports from expert witnesses (n=48, 1980-2007) from the German regions around Munich and Rostock were analyzed retrospectively in order to identify sociodemographic, clinical and forensic characteristics of child murders. In 87.5% of the cases the victims were the natural children of which 25 were younger than 1 year old. Female offenders outnumbered male offenders by 3:1 and on average females were 8 years younger than males (26.5 years for females and 34.2 years for males). The motives included unwanted pregnancy/child, altruistic deeds, acute psychoses, child abuse (sexual abuse, neglect or negligence), drug or alcohol abuse, sadistic punishment of the child and revenge on partners. In 27 cases a restricted or exemption from criminal responsibility was acknowledged. About one third of the offenders consulted a physician before the crime. For an improvement in primary prevention, support networks should be integrated and sensitized to the problem.

  15. På vej mod en dansk krondyrforvaltning (Cervus elaphus): Hvad mangler vi at vide, og hvad mangler vi at gøre?

    DEFF Research Database (Denmark)

    Sunde, Peter; Haugaard, Lars

    2014-01-01

    bestanden og jagtudbyttet på, vil være at frede de unge hjorte mod at have fri jagt på dem, som har nået ”høstklar” alder. Ud over at sikre jægerne et bedre udbytte vil en sådan ”mindstemålsmodel” modvirke selektion for tidligere kønsmodenhed og mindre kropstørrelse for hjorte. In Denmark, red deer (Cervus....... We compared the harvest outcome and demographic composition of these theoretical models with two Danish red deer populations with contrasting land owner structure and hunting regimes (Djursland and Oksbøl). Djursland (hunting seasons 2008/9-2012/13) represents a ‘typical’ Danish landscape, comprising...... multiple owners of small or larger estates each of which run their own hunting practices. In this area, 1-year old males were protected in an effort to increase the proportion of mature stags in the population. The population on Oksbøl (1985/86-2012/13) is managed by the Danish Nature Agency, with the aim...

  16. Timing of the maturation transition in haddock Melanogrammus aeglefinus.

    Science.gov (United States)

    Tobin, D; Wright, P J; O'Sullivan, M

    2010-10-01

    The timing of maturation in haddock Melanogrammus aeglefinus was examined using changes in gonad development, follicle stimulating hormone β (FSH-β) transcript expression profile, growth and condition of 1 year old females held under a common environment between the summer and winter solstices. The circumnuclear ring, cortical alveolus and vitellogenic oocyte stages were first observed in August, October and November, respectively. FSH-β transcript levels did not change significantly until September but increased markedly thereafter in maturing fish. A combined analysis of the mean oocyte diameter of the leading cohort, histological staging and FSH-β transcript profile provided evidence of a commitment to maturation by October or November. Contrary to that previously proposed for gadoid species, histological analysis of field-caught immature M. aeglefinus during the spawning season indicated that cortical alveolar, rather than circumnuclear ring, stage oocytes provided definitive evidence of maturation. A decrease in relative liver size following the summer solstice suggested a possible link between energy status and maturation.

  17. Radial tear of posterior horn of the medial meniscus and osteonecrosis of the knee

    International Nuclear Information System (INIS)

    We studied the relation between a radial tear of the posterior horn of the medial meniscus and osteonecrosis of the knee. Thirty-eight knees of 37 patients were diagnosed as medial meniscus tear and received arthroscopic knee surgery. We divided them into two groups: knees having radial tear of the posterior horn of the medial meniscus (posterior horn group) and knees containing radial tear except for posterior horn, horizontal tear, degenerative tear, and flap tear of the medial meniscus (non-posterior horn group). The posterior horn group consisted of 14 knees (average age: 65.1 years old) and the non-posterior horn group consisted of 24 knees (average age: 59.6 years old). All cases underwent MRI before arthroscopy. MRI findings were classified into three types (typical osteonecrosis, small osteonecrosis, and non-osteonecrosis). In the posterior horn group, typical osteonecrosis were five knees and small osteonecrosis were five knees, while in the non-posterior horn group only three knees were small osteonecrosis. These findings suggest the relevance between radial tear of the posterior horn of the medial meniscus and osteonecrosis of the knee (Mann-Whitney test p<0.01). The etiology of spontaneous osteonecrosis of the knee joint is unknown, however one etiology could be the radial tear of the posterior horn of the medial meniscus. (author)

  18. Influence of Marriage and Parenthood on Physical Activity: A 2-Year Prospective Analysis

    Science.gov (United States)

    Hull, Ethan Edward; Rofey, Dana L.; Robertson, Robert J.; Nagle, Elizabeth F.; Otto, Amy D.; Aaron, Deborah J.

    2011-01-01

    Background Physical activity (PA) tends to decrease from adolescence to young adulthood, and factors that have been proposed to contribute to this decrease are life transitions. The focus of this study is to examine life transitions, such as marriage and parenthood, and the impact they may have on the physical activity levels of young adults. Methods This 2-year prospective analysis assessed physical activity (hrs/wk) and sociodemographics in young adults (n = 638, 48% male, 15% nonwhite, 24 ± 1.1 years old) via questionnaire. PA data were normalized through log transformations and examined using ANCOVAs, controlling for appropriate covariates. Results ANCOVA results showed that becoming married did not significantly change PA compared with individuals who stayed single [F(1,338) = 0.38, P = .54, d = 0.06]. Conversely, PA was significantly lower [F(1,517) = 6.7, P = .01, d = 0.41] after having a child, compared with individuals who stayed childless. Conclusions These results suggest that marriage does not impact PA in young adults, but having a child significantly decreases PA in parents, and may offer an optimal period of intervention. PMID:20864752

  19. Improved Prefrontal Activity and Chewing Performance as Function of Wearing Denture in Partially Edentulous Elderly Individuals: Functional Near-Infrared Spectroscopy Study

    Science.gov (United States)

    Kamiya, Kazunobu; Narita, Noriyuki; Iwaki, Sunao

    2016-01-01

    The purpose of this study was to elucidate the effects of wearing a denture on prefrontal activity during chewing performance. We specifically examined that activity in 12 elderly edentulous subjects [63.1±6.1 years old (mean ± SD)] and 12 young healthy controls (22.1±2.3 years old) using functional near-infrared spectroscopy (fNIRS) in order to evaluate the quality of prefrontal functionality during chewing performance under the conditions of wearing a denture and tooth loss, and then compared the findings with those of young healthy controls. fNIRS and electromyography were used simultaneously to detect prefrontal and masticatory muscle activities during chewing, while occlusal force and masticatory score were also examined by use of a food intake questionnaire. A significant increase in prefrontal activity was observed during chewing while wearing a denture, which was accompanied by increased masticatory muscle activity, occlusal force, and masticatory score, as compared with the tooth loss condition. Prefrontal activation during chewing while wearing a denture in the elderly subjects was not much different from that in the young controls. In contrast, tooth loss in the elderly group resulted in marked prefrontal deactivation, accompanied by decreased masticatory muscle activity, occlusal force, and masticatory score, as compared with the young controls. We concluded that intrinsic prefrontal activation during chewing with a denture may prevent prefrontal depression induced by tooth loss in elderly edentulous patients. PMID:27362255

  20. Imaging abusive head trauma: why use both computed tomography and magnetic resonance imaging?

    International Nuclear Information System (INIS)

    Abusive head trauma is the leading cause of death in child abuse cases. The majority of victims are infants younger than 1 year old, with the average age between 3 and 8 months, although these injuries can be seen in children up to 5 years old. Many victims have a history of previous abuse and the diagnosis is frequently delayed. Neuroimaging is often crucial for establishing the diagnosis of abusive head trauma as it detects occult injury in 37% of cases. Several imaging patterns are considered to be particularly associated with abusive head trauma. The presence of subdural hematoma, especially in multiple locations, such as the interhemispheric region, over the convexity and in the posterior fossa, is significantly associated with abusive head trauma. Although CT is the recommended first-line imaging modality for suspected abusive head trauma, early MRI is increasingly used alongside CT because it provides a better estimation of shear injuries, hypoxic-ischemic insult and the timing of lesions. This article presents a review of the use and clinical indications of the most pertinent neuroimaging modalities for the diagnosis of abusive head trauma, emphasizing the newer and more sensitive techniques that may be useful to better characterize the nature and evolution of the injury. (orig.)

  1. Product estimate of air kerma-area and the air kerma in the input surface of the skin of pediatric patients undergoing chest X-ray; Estimativa do produto kerma ar-area e do kerma ar na superficie de entrada da pele de pacientes pediatricos submetidos a radiografia de torax

    Energy Technology Data Exchange (ETDEWEB)

    Villa-Chan, Beatriz; Carvalho, Aline; Andrade, Marcos Ely A.; Barros, Vinicius S.M. de; Khoury, Helen J., E-mail: beatrizvillachan@gmail.com, E-mail: alinecx90@gmail.com, E-mail: marcos.ely@gmail.com, E-mail: vsmdbarros@gmail.com, E-mail: hjkhoury@gmail.com [Universidade Federal de Pernambuco (UFPE), Recife, PE (Brazil). Dept. de Energia Nuclear

    2014-07-01

    The aim of this paper is to evaluate the entrance air kerma (Ka,e) and the product air kerma-area (Pka) for chest examinations performed with pediatric patients in a large public hospital of Recife. For this study 89 examinations of patient with ages from zero to 10 years old were evaluated. The results showed that the mean Ka,e values, for patients of 0-1 years old, 1-5 years old and 5-10 years old, were, respectively, 100 mGy, 120 mGy and 100 mGy. The Pka values for newborn patients range from 11,9 to 58,4 mGy.cm{sup 2}, for patients with 1 to 5 years old range from 17 to 192 mGy.cm{sup 2}, and from 30,4 to 136,2 mGy.cm{sup 2} for patients with ages from 5 to 10 years old. The differences in the Pka values are due the different dimensions of the radiation field. For the results its possible to conclude that the Pka values are high, in special for patients with ages from 1 to 5 years old, indicating that the collimation of the radiation field is not adequate. (author)

  2. Grassland carbon sequestration and emissions following cultivation in a mixed crop rotation

    DEFF Research Database (Denmark)

    Acharya, Bharat Sharma; Rasmussen, Jim; Eriksen, Jørgen

    2012-01-01

    -old grassland and a pea field as reference. Aboveground and root biomass were determined and soils were incubated to study CO2 emissions after soil disturbance. Aboveground biomass was highest in 1-year-old grassland with slurry application and lowest in 4-year-old grassland without slurry application. Root...... biomass was highest in 4-year-old grassland, but all 1–4-year-old grasslands were in between the pea field (0.81 ± 0.094 g kg−1 soil) and the 17-year-old grassland (3.17 ± 0.22 g kg−1 soil). Grazed grasslands had significantly higher root biomass than cut grasslands. There was no significant difference...... in the CO2 emissions within 1–4-year-old grasslands. Only the 17-year-old grassland showed markedly higher CO2 emissions (4.9 ± 1.1 g CO2 kg−1 soil). Differences in aboveground and root biomass did not affect CO2 emissions, and slurry application did not either. The substantial increase in root biomass...

  3. Growth and the modeling/remodeling of the alveolar bone of the rat incisor.

    Science.gov (United States)

    Merzel, José; Salmon, Cristiane R

    2008-07-01

    The modeling and remodeling of the rat incisor alveolar bone was followed as the animals grew. The weight of the hemimandible, the length of the socket, and the width of the lower incisor were measured. Osteoclasts and resorption areas were identified by tartrate-resistant acid phosphatase staining. Fluorochrome markers were used to detect and measure osteogenic activities. In the socket related to the periodontal ligament, osteoclasts appeared in scattered sites as well as isolated sites of osteogenic activity, apparently without any variation related to the age of the animals. At the socket facing the dental follicle of young rats, the inner surface was lined with osteoclasts. The number of osteoclasts decreased steadily as the rats grew. In 1-year-old rats, in addition to a few scattered osteoclasts, the internal aspect of the labial wall showed some sites lined with osteoblasts and cement lines indicative of prior bone formation. In young rats, there was a continuous osteogenic activity at the external surface of this wall. The thickness of the labial wall of the socket remained apparently constant; therefore, bone resorption must have occurred at the internal side of the wall. Such osteogenic activity was not observed in old rats. The main forces acting on rat incisors, biting and eruption, are continuous through the life of the animals. Thus, these results indicate that the modeling of the alveolar bone related to the dental follicle, in young rats, can only be associated with another force, specifically, the growth of the incisor. PMID:18461598

  4. [Major features of decline of Pinus sylvestris var. mongolica plantation on sandy land].

    Science.gov (United States)

    Wu, Xiangyun; Jiang, Fengqi; Li, Xiaodan; Xue, Yang; Qiu, Sufen

    2004-12-01

    In view of the decline of man-made sand-fixation forest of Pinus sylvestris var. mongolica in Zhanggutai sand land of Liaoning Province, this paper studied the major characteristics of the decline. The appearance of the declining man-made sand-fixation forest of Pinus sylvestris var. mongolica was grey green, its needle leaf was very thin, the blooming and fruiting rate was low, the average quantity of cones per tree was only 10.4-16.5, with only 6.96 g to 7.39 g per thousand seeds, and there were many empty and astringent seeds. The seasonal dynamics of nutrients in 2-year-old pine needle leaf was similar, i.e., the N and P contents decreased, while K content increased, showing that the nutrient cycle was imbalance. The chlorophyll content in 2-year-old needle leaf of declined forest was high, while that in 1-year-old healthy forest was also high but with a wide increasing range. The infected harm of shoot blight was the clearest mark to the decline of man-made sand-fixation forest of Pinus sylvestris var. mongolica. After the forest declined, the height and the DBH of the pine trees decreased evidently, and the structure of DBH distribution moved "left". The quantity of weak pine trees increased by 15.9%-27.2%, the roots decreased by 22.9%-28.9%, and the absorbing roots (diameter < 0.5 cm) decreased most seriously. PMID:15825430

  5. [Effects of artificial tending on Pinus tabulaeformis forest growth and its structural characteristics].

    Science.gov (United States)

    Cao, Yun; Yang, Yie; Song, Bingyu; Huang, Heping; Yang, Mingbo; Zheng, Min

    2005-03-01

    The investigation on the growth status, community composition, and structural characteristics of Pinus tabulaeformis forest artificially tended for six years showed that there were significant differences in the average DBH, height, and crown size of the forest among the treatments DA (trimming without intermediate cutting), FA (trimming and intermediate cutting) and CK (without trending). Treatment FA had the highest values of average DBH (7.8 +/- 0.29 cm), height (5.5 +/- 0.09 m) and crown size (249 +/- 7.24 cm), while the CK had the lowest ones. The average biomass of new leaf (1-year-old), old leaf (2 or more-year-old), and branch per tree increased significantly (P<0.01) with enhancing tending treatments. The aboveground biomass of treatment FA was the biggest (44.0 t x hm(-2)), and that of CK was the smallest (14.9 t x hm(-2)). The leaf length and SLA at the early and terminal stages of development (May, June and September) had significant difference among the treatments, and the amount of community composition and the cover degree of undergrowth plants increased evidently under artificial tending treatments. PMID:15943345

  6. Age-related changes in semen quality characteristics and expectations of reproductive longevity in Duroc boars.

    Science.gov (United States)

    Huang, Yu Hung; Lo, Ling Ling; Liu, Shyh Hwa; Yang, Tien Shuh

    2010-08-01

    Quadratic fitting was used to regress semen characteristics of 1441 samples consisting of 12-month collection from 58 Duroc boars against animal age varied from 10 to 80 months. Data was divided into two groups of cool (14.0-22.7 degrees C, RH 81.5%) and hot season (22.9-29.9 degrees C, RH 86.6%), to test effects of age, season and their interactions. Results revealed that young boars of around 1 year old could endure the hot season. The endurance gradually diminished as animals grew. In the hot season animals exhibited peak performance at age around 33 month and it remained for 1 month, while cool-season kept boars could last for 48 months from 16 months old onward. The reproductive longevity should be 51 month in a subtropical environment and it may extend to 70 month if heat stress can be avoided. The estimated total sperm contribution of a Duroc boar would be 1.8 times more when kept below 22 degrees C than in a natural subtropical environment. It is concluded that to maintain Duroc boars as semen donor to at least 4 years of age is feasible in a subtropical environment and boar longevity could reach 6 years old if well kept in a temperate region. PMID:20662811

  7. Seasonal and Tissue Age Influences on Endophytic Fungi of Pinus tabulaeformis (Pinaceae) in the Dongling Mountains,Beijing

    Institute of Scientific and Technical Information of China (English)

    Liang-Dong Guo; Guo-Rui Huang; Yu Wang

    2008-01-01

    Endophytic fungi associated with Pinus tabulaeformis Carr.were investigated in the Dongling Mountains of Beijing.A total of 16200 tissue segments of P.tabulaeformis from four sample collections were processed,and 10659 fungal isolates were recovered.The overall colonization and isolation rates of endophytic fungi from high to low were spring>winter>autumn>summer and in different tissues were bark>needle>xylem,irrespective of sampling seasons.The colonization rates of endophytic fungi of needles increased with age in the four sample collections.There were no significant differences of the colonization rates of endophytic fungi among 1-,2-,and 3-year-old bark and xylem,except for significantly lower colonization rates in 1-year-old bark than in 2- and 3-year-old bark in summer.A similar trend of the isolation rates of endophytic fungi occurred.A total of 24 fungal taxa were recorded,of these five taxa Alternaria alternata,Leptostroma sp.,Pestalotiopsis besseyi,Phoma lingam,and Phomopsis archeri,were consistently isolated as the common fungi in each sample collection.Our results suggest that some fungi show a certain degree of tissue recurrence or specificity,and the composition of endophytic assemblages is not conspicuously influenced by the seasonal factor.

  8. Aspectos dos líquidos cefalorraquidianos nas meningites bacterianas

    Directory of Open Access Journals (Sweden)

    Claudia E. O. Pires de Campos

    1994-06-01

    Full Text Available Foram colhidos 1815 líquidos cefalorraquidianôs de doentes internados com meningite, no Hospital Emílio Ribas, São Paulo, durante os meses de maio a outubro de 1989. Neisseria meningitidis 56%, dos quais 44% do tipo B; Haemophilus influenzae 17%, sendo 72 % isoladas de neonatos até 3 anos; Streptococcus pneumoniae 14%, dos quais 60% isolados de recém nascidos a 1 ano de idade. O estudo citoquímico liquórico mostrou: celularidade: global > 500cel/mm³ e específica > 70%; proteínas > 90mg/dl e glicose Samples of 1815 cerebrospinal fluid (CSF were studied in a meningitis outbreak during 1989 in São Paulo, Brazil. Neisseria meningitis 56% with 44% type B, Haemophilus influenzae 17%, from which 72% in children (days to 3-year old and Streptococcus pneumoniae 14% from which 60% in children (day to 1- year old of443 (24 %of allstrains. Cytochemistry study showed: purulent or turbidity aspects in 70 to 79% positive bacterioscopy or culture of CSF; white cells count > 500/mm³; glucose 90mg/dl in 90% of all patients. We concluded that: CSF prognostic factors: (aspect and cytochemistry were correlated with bacterial meningitis. Bacterioscopy and positive cultures were correlated to NM, SP and HI isolation from these patients (Goodman Test.

  9. Pulmonary arterial hypertension associated with bronchopulmonary dysplasia and congenital heart disease in preterm infants. A case report of a preterm infant with recurrent pulmonary hypertension after corrective cardiac surgery and review of the literature.

    Science.gov (United States)

    Muneuchi, Jun; Kuraoka, Ayako; Watanabe, Mamie; Ochiai, Yoshie; Joo, Kunitaka

    2015-01-01

    In preterm infants with congenital heart disease, concomitant bronchopulmonary dysplasia (BPD) is associated with relatively poor clinical outcomes because of the increased pulmonary vascular resistance and adverse effects of inflammation on the damaged lungs, even after surgery. We present herein a 1-year-old female who developed recurrent pulmonary arterial hypertension 6 months after closure of a ventricular septal defect. She was born at 26 weeks of gestation (birth weight, 470 g), and developed BPD requiring oxygen supplementation. Her systemic-to-pulmonary blood flow ratio was 2.1 preoperatively and 1.0 postoperatively, pulmonary arterial pressure was 61/15 (mean 39) mmHg preoperatively and 41/17 (mean 24) mmHg postoperatively, and pulmonary vascular resistance was 4.2 mmHg/L·minute·m(2) preoperatively and 3.6 mmHg/L·minute·m(2) postoperatively. At 1 year of age, echocardiography showed an increase in her estimated right ventricular pressure, indicating worsening pulmonary hypertension. After 3 years of treatment with oxygen supplementation, prostacyclin, and bosentan, her pulmonary arterial pressure improved to the normal range. The pathophysiology of pulmonary arterial hypertension is heterogeneous in preterm infants with congenital heart disease and concomitant BPD. Careful management of these patients is warranted even after corrective cardiac surgery.

  10. PALMILHAS PROPRIOCEPTIVAS PARA O CONTROLE POSTURAL

    Directory of Open Access Journals (Sweden)

    Alessandra Madia Mantovani

    2010-12-01

    Full Text Available The postural control and balance depend of the sensory system and musculoskeletal biomechanics being the feet one of the main sensors of the sensory system. The aim were to evaluate postural control and plantar pressures before, during and after the use of proprioceptive insoles. Participated 15 subjects, age 19,62,1 years old, and body mass índex (BMI of 24,45,4 kg/m2. Postural assessment values have been measured the arrows on the spine curvature, followed by analysis of plantar pressures and measures for pedobarometricstabilometric for measuring of displacement of center of pressure before, during andafter the use of insoles. In the results we saw normal arrows post insole plantar pressureand stabilometry not statistically significant after its use. Conclued that after using these insole, was saw an adequate postural realignment, probably due to adequate muscle and posture tonedemonstrating the importance of assessing the captor podal for understanding postural disordens.

  11. Animal-Assisted Activities: Results From a Survey of Top-Ranked Pediatric Oncology Hospitals.

    Science.gov (United States)

    Chubak, Jessica; Hawkes, Rene

    2016-07-01

    Animal-assisted activities (AAA) are increasingly common, yet little is known about practices in pediatric oncology. To address this gap, we surveyed the top 20 pediatric oncology hospitals in the United States in May and June of 2014. Questionnaires were sent via e-mail and generally returned by e-mail or postal mail. Among the 19 responding hospitals, the 18 that offered AAA to pediatric patients formed the basis of our analysis. All sites had written AAA policies. Most programs were restricted to dogs. At 11 hospitals, children with cancer could participate in AAA activities. Outpatient waiting rooms and individual inpatient rooms were the most common locations for AAA with pediatric oncology patients. Safety precautions varied by hospital, but all required hand sanitation after visits and that animals receive an annual health examination, be on a leash or in a carrier, be ≥1 year old, and not be directly from a shelter. Our findings reveal consistencies and variations in practice that may help other hospitals develop their own programs and researchers identify areas of future study. PMID:26589356

  12. Genome-Wide Transcriptional Profile Analysis of Prunus persica in Response to Low Sink Demand after Fruit Removal.

    Science.gov (United States)

    Duan, Wei; Xu, Hongguo; Liu, Guotian; Fan, Peige; Liang, Zhenchang; Li, Shaohua

    2016-01-01

    Prunus persica fruits were removed from 1-year-old shoots to analysis photosynthesis, chlorophyll fluorescence and genes changes in leaves to low sink demand caused by fruit removal (-fruit) during the final stage of rapid fruit growth. A decline in net photosynthesis rate was observed, accompanied with a decrease in stomatal conductance. The intercellular CO2 concentrations and leaf temperature increased as compared with a normal fruit load (+fruit). Moreover, low sink demand significantly inhibited the donor side and the reaction center of photosystem II. 382 genes in leaf with an absolute fold change ≥1 change in expression level, representing 116 up- and 266 down-regulated genes except for unknown transcripts. Among these, 25 genes for photosynthesis were down-regulated, 69 stress and 19 redox related genes up-regulated under the low sink demand. These studies revealed high leaf temperature may result in a decline of net photosynthesis rate through down-regulation in photosynthetic related genes and up-regulation in redox and stress related genes, especially heat shock proteins genes. The complex changes in genes at the transcriptional level under low sink demand provided useful starting points for in-depth analyses of source-sink relationship in P. persica.

  13. Prevalence of intestinal helminthes in owned dogs in Kerman city, Iran

    Institute of Scientific and Technical Information of China (English)

    Mohammad Mirzaei; Majid Fooladi

    2012-01-01

    Objective:To survey the prevalence of canine gastrointestinal helminthes in dogs presented to theVeterinary faculty of theUniversity ofKerman betweenMay andNovember2011.Methods:A total of70 fecal samples were evaluated by the fecal sedimentation method.Results:The prevalence of gastrointestinal helminthes was7.14%.The parasites most frequently detected were Toxocara canis (T. canis)(4.3%);Toxascaris leonina (T. leonina)(1.4%) andTeania spp.(1.4%). The age distribution of intestinal parasites in dogs showed that the dog less than1 year old had a higher overall prevalence than those dogs over12 months of age but there was not significant (P>0.05).Also there was no significant difference in the prevalence between male(7.7%) and female(6.5%) dogs(P>0.05).Conclusions:It is thought that the reduction in the frequency of the dogs with those helminthes may be mainly a result of the improvement in breeding environment and the routine use of antihelmintics.The significance of zoonotic diseases caused by intestinal helminthes makes it necessary for us to know the infection status of domestic dogs and to take measures for further control.It is concluded that veterinarians have an important role in educating dog owners of these potential risks and means forpreventing or minimizing zoonotic transmission.

  14. Aging and iron accumulation in the monkey brain

    International Nuclear Information System (INIS)

    Iron is deposited in the mammalian brain with a characteristic distribution, its amount increasing with aging. The relative abundance of iron in the globus pallidus, substantia nigra and putamen is thought to be responsible for the hypointensity of these nuclei on T2-weighted MR images, due to magnetic susceptibility effects. However, no quantitative correlation between iron content and hypointensity has been made to confirm this hypothesis. Two young (1-year-old) and two older (18-year-old) rhesus monkeys were studied with MR imaging at different field strengths (0.5, 1.5, 2.0 T). MR signal intensities from different anatomic structures were measured on T2-weighted coronal images (2,6000/80 [repetition time msec/echo time msec]). At completion of the MR studies, the monkeys were killed, coronal brain sections were stained for iron (Perls method), and optical densities of anatomic structures were measured. A quantitative correlation between the iron content and the signal intensity decrease was found on T2-weighted images in both deep and superficial cerebral structures. The detectability of magnetic susceptibility effects in a single structure is determined by the amount of iron present, with the threshold being inversely correlated to the strength of the magnetic field

  15. Association of cytogenetics and immunophenotype in prognosis of children with acute lymphoblastic leukemia: Literature Review

    Directory of Open Access Journals (Sweden)

    Abdollah Banihashem

    2014-02-01

    Full Text Available Acute lymphoblastic leukemia (ALL is the most common type of neoplastic disorder diagnosed in childhood. It is the cause of one third of all pediatric malignancies. ALL is characterized by the abnormal production and proliferation of immature lymphoblasts in bone marrow (BM. It seems that ALL occurs due to a genetic mutation in DNA structure producing white blood cell (WBC stem cells. Because ALL is a systemic disease, its primary management is based on chemotherapy. There are important risk factors responsible for the poor prognosis of  ALL in children less than 1 year old and greater than 10 years old, such as: high WBC, mature T cell ,mature B cell, central nervous system (CNS involvement, DNA index 10 at diagnosis, no remission at the end of induction therapy and Minimal residual disease at the end of consolidation therapy. Complications might appear during the treatment including tumor lysis syndrome, bleeding, renal failure, sepsis, seizure, thrombosis, etc. Some consequences might identify after a long-term follow-up such as learning impairment, growth retardation, and secondary malignancies. It is estimated that up to 90% of pediatric ALL cases are curable.

  16. Identification of the secondary follicle cycle of Hexi cashmere goat.

    Science.gov (United States)

    He, Yanyu; Cheng, Lixiang; Wang, Jiqing; Liu, Xiu; Luo, Yuzhu

    2012-09-01

    This experiment conducted to identify a periodic change of ultrastructures of secondary follicle characteristics during a whole year, reveal the molecule regulation of growth of cashmere. A total of 10 cashmere goats of 1-year old were studied. The paraffin section and ultrathin slices of skin were made each month in a whole year, observed, photographed, and analyzed under light microscope and transmission electron microscope after stained. Following the development of down fiber, the ultrastructures of secondary follicle of Hexi cashmere goat showed a periodic change within a year. There were five different periods during a down fiber cycle. It was observed that the stage of telogen, proanagen, anagen, procatagen, and catagen was in January and February, March and April, May to August, September and October, and November and December, respectively. The key change observed in secondary follicle under transmission electron microscope was inner root sheath. This study illustrated the five different stage of secondary follicle of Hexi Cashmere goat within a whole growth cycle, and has provided more detailed information about the research field of Hexi cashmere goat. Choosing the suitable time to harvest the cashmere may get the profit maximization. PMID:22753049

  17. Growth and carbohydrate status of coppice shoots of hybrid poplar following shoot pruning.

    Science.gov (United States)

    Tschaplinski, T J; Blake, T J

    1995-05-01

    Fifteen, 1-year-old Populus maximowiczii Henry x P. nigra L. 'MN9' trees were decapitated and allowed to sprout. After 8 weeks, all had 6 to 10 coppice shoots. All shoots, except the tallest (dominant) shoot, were removed from five of the trees (pruned treatment), and shoot growth, gas exchange and carbohydrate status were compared in the pruned and unpruned trees. Although photosynthetic rate of recently mature leaves of pruned trees was approximately 50% greater than that of leaves on the dominant shoot of unpruned trees, and the dry weight of leaves of pruned trees was 37% greater than that of the leaves on the dominant shoot of unpruned trees, the shoot dry matter relative growth rate did not differ between treatments. Concentrations of water-soluble carbohydrates and starch in the uppper stem and leaves of the dominant shoot were similar in pruned and unpruned trees. However, relative to that of the dominant shoot in unpruned trees, the lower stem in pruned trees was depleted in both soluble carbohydrates and starch. Starch deposition, assessed as the quantity of (14)C-starch in tissues 24 h after a fully expanded source leaf was labeled with (14)CO(2), was 3.9 times greater in roots of pruned trees than in roots of unpruned trees. We conclude that early removal of all but the dominant shoot reduces the carbohydrate status of the roots and the lower portion of the stem by eliminating the excised shoots as a source of photosynthate.

  18. 五加的扦插繁殖研究%Study on Cuttage of Acanthopanax gracilistylus W. W. Smith

    Institute of Scientific and Technical Information of China (English)

    王仕玉; 郭凤根

    2001-01-01

    The influence of matrices and IBA treatments on cuttage of old and young branches of Acanthopanax gracilistylus W. W. Smith was studied by using Orthogonal Design with 3 factors and 2 levels. The results were as follows : Quicksets of 2 or 3 years old are better than those of 1 year old for cuttage. Mixed matrix of sand and red soil give better cuttage effects than that of perlite and humus. It can increase the radication and sprout rates of quicksets of Acanthopanax gracilistylus W. W. Smith dipped quicksets in 1 000 mg/kg IBA for 10 sec.%采用3因子2水平正交试验设计,探讨了不同扦插基质和IBA处理对五加老枝和嫩枝扦插繁殖的影响,结果表明:二年生或三年生插条优于当年生插条;河沙和红土的混合基质优于珍珠岩和腐殖土的混合基质;用1 000mg/LIBA蘸插条10 s(秒)能提高五加插条的生根率和发梢率。

  19. The Association of IFI27 Expression and Fatigue Intensification during Localized Radiation Therapy: Implication of a Para-Inflammatory Bystander Response

    Directory of Open Access Journals (Sweden)

    Leorey N. Saligan

    2013-08-01

    Full Text Available The mechanisms behind fatigue intensification during cancer therapy remain elusive. The interferon alpha-inducible protein 27 (IFI27 was the most up-regulated gene based on our previous microarray data in fatigued men with non-metastatic prostate cancer receiving localized external beam radiation therapy (EBRT. The purpose of this study was to confirm the IFI27 up-regulation and determine its association with fatigue intensification during EBRT. Peripheral blood samples and fatigue scores were collected at three time points—prior to EBRT, at midpoint, and at completion of EBRT. Confirmatory quantitative real time polymerase chain reaction (qPCR and enzyme-linked immunosorbent assay (ELISA were utilized to verify the microarray results. Subjects were a total of 40 Caucasian men with prostate cancer; 20 scheduled for EBRT (65.6 ± 7.5 years old, and 20 on active surveillance as controls (62.8 ± 6.1 years old. Significant IFI27 expression overtime during EBRT was confirmed by qPCR (p < 0.5, which correlated with fatigue scores during EBRT (R = −0.90, p = 0.006. Alterations in mechanisms associated with immune response and mitochondrial function that explain the up-regulation of IFI27 may provide an understanding of the pathways related to the intensification of fatigue during localized radiation therapy.

  20. Japanese macaque (Macaca fuscata) mothers huddle with their young offspring instead of adult females for thermoregulation.

    Science.gov (United States)

    Ueno, Masataka; Nakamichi, Masayuki

    2016-08-01

    It is unclear whom animals select to huddle with for thermoregulation. In this study, we investigated whom Japanese macaque (Macaca fuscata) mothers huddled with-their young offspring or other adult group members-when there is need for thermoregulation. We used a focal-animal sampling method, targeting 17 females at Katsuyama, Okayama Prefecture, Japan. A majority of huddling among adult females was recorded during winter season (December, January, and February). Females who had young (0- or 1-year-old) offspring huddled less frequently with other adult females compared to females who did not have young offspring in winter. However, including young offspring, the frequency of huddling with any other individuals did not differ by whether females had young offspring. Moreover, the females who did not have young offspring huddled with other adult females more often in cloudy than in sunny weather during winter season. In contrast, females who had young offspring increased huddling with their young offspring in cloudy than in sunny weather, but did not do so with other adult females. This study indicates that Japanese macaque mothers huddle with their young offspring instead of other adult females when there is need for thermoregulation. PMID:27262980

  1. Diversity of Gut Microbiota Metabolic Pathways in 10 Pairs of Chinese Infant Twins

    Science.gov (United States)

    Wang, Yan; Zhou, Jianli; Zhou, Wenhao

    2016-01-01

    Early colonization of gut microbiota in human gut is a complex process. It remains unclear when gut microbiota colonization occurs and how it proceeds. In order to study gut microbiota composition in human early life, the present study recruited 10 healthy pairs of twins, including five monozygotic (MZ) and five dizygotic (DZ) twin pairs, whose age ranged from 0 to 6 years old. 20 fecal samples from these twins were processed by shotgun metagenomic sequencing, and their averaged data outputs were generated as 2G per sample. We used MEGAN5 to perform taxonomic and functional annotation of the metagenomic data, and systematically analyzed those 20 samples, including Jaccard index similarity, principle component, clustering, and correlation analyses. Our findings indicated that within our study group: 1) MZ-twins share more microbes than DZ twins or non-twin pairs, 2) gut microbiota distribution is relatively stable at metabolic pathways level, 3) age represents the strongest factor that can account for variation in gut microbiota, and 4) a clear metabolic pathway shift can be observed, which speculatively occurs around the age of 1 year old. This research will serve as a base for future studies of gut microbiota-related disease research. PMID:27583441

  2. Impact of Obesity and Underweight on Surgical Outcome of Lumbar Disc Herniation

    Directory of Open Access Journals (Sweden)

    Farzad Omidi-Kashani

    2014-01-01

    Full Text Available Background. The relationship between underweight and lumbar spine surgery is still unknown. Aim. To evaluate the effect of underweight versus obesity based on surgical outcome of lumbar disc herniation. Material and Method. In this retrospective study, we evaluated 206 patients (112 male and 94 female with a mean age of 37.5±3.1 years old (ranged 20–72 who have been surgically treated due to the refractory simple primary L4-L5 disc herniation. We followed them up for a mean period of 42.4±7.2 months (ranged 24–57. We used Body Mass Index (BMI, Oswestry Disability Index (ODI, and Visual Analogue Scale (VAS for categorization, disability, and pain assessment, respectively. We used Wilcoxon and Mann-Whitney U tests for statistics. Results. Surgical discectomy in all weight groups was associated with significant improvement in pain and disability, but intergroup comparison showed these improvements in both underweight and obese groups and they were significantly lower than in normal weight group. Excellent and good satisfaction rate was also somewhat lower in both these ends of weight spectrum, but statistically insignificant. Conclusion. Both obesity and underweight may have adverse prognostic influences on the surgical outcome of lumbar disc herniation, although their impact on subjective satisfaction rate seems to be insignificant.

  3. Increasing rate of middle ear ventilation tube insertion in children in denmark

    DEFF Research Database (Denmark)

    Djurhuus, Bjarki Ditlev; Skytthe, Axel; Christensen, Kaare;

    2014-01-01

    ventilation tube insertions distributed among 269,459 different children were identified. From 1997 to 2010 the age standardized incidence rate in 0-15-year-olds increased from 26 to 40 per 1000 person years with an estimated annual increase of 2.0% (95% confidence interval 1.9-2.1%). The largest increase......OBJECTIVE: To study the incidence rates of middle ear ventilation tube insertion in children aged 0 to 15 years in Denmark from 1997 to 2010. METHODS: Using two national registers, the Danish National Health Service Register and the Danish National Patient Register, practically all cases of middle...... in incidence rate was found in 1-year-olds with an annual increase of 4.5% (95% confidence interval 4.4-4.6%). Age-specific incidence rates remained at maximum around the age of 14 months throughout the period. The cumulative incidence proportion for the 2010 birth cohort by the time they reach the age of 5...

  4. Risk factors in pediatric asthmatic patients. Cases and control studies.

    Directory of Open Access Journals (Sweden)

    Rafael Alejandro Gómez Baute

    2003-04-01

    Full Text Available Background: Asthma constitutes the first disease among chronic diseases in children. The morbid-mortality promoted to continue being elevated in spite of the new therapies. For this reason it is a disease with high priority for investigation in pediatric ages. Method: A control and case group study was carried out. The samples was composed by 72 asthmatic children from three General Comprehensive doctor offices from Palmira health area located in Cienfuegos Province, Cuba; and a control group of 72 children apparently healthy from the same population. A questionnaire with the different risk variables was elaborated. Odds ratio technique was used to estimate the risk. Results: low weight at birth, family history of asthma, brochiolitis antecedent and the excessive usage of antibiotics in children under 1 year old were the main risks found. Conclusions: It is conclusive that the exposure to home allergen plus a genetic favorable factor, the prematurity, and brochiolitis constituted the most outstanding elements to suffer from asthma in the population studied.

  5. A longitudinal group study of speech development in Danish children born with and without cleft lip and palate.

    Science.gov (United States)

    Hutters, B; Bau, A; Brøndsted, K

    2001-01-01

    The present study focuses on contoid vocalization by Danish 1-year-old unrepaired toddlers born with cleft lip and palate, and how they differ from their non-cleft peers. Furthermore, we focus on how the same children master Danish consonants at 3 years of age compared with their non-cleft peers in terms of their ability to produce consonants in accordance with adult target. Also, with the 3 year olds, we look at cleft speech characteristics as well as developmental speech characteristics found in both groups of children. Based on phonetic transcription, it was found that Danish unoperated cleft palate children at 1 year of age produced few types of contoids and preferably contoids that did not require closure of the velopharyngeal port in their prespeech. In addition, the data suggest that consonants produced by cleft children who are treated with one-stage surgery after speech onset, at 3 years of age differ from speech produced by non-cleft children, not only as regards cleft speech characteristics, but also as regards developmental speech characteristics.

  6. Dermal mass aspirate from a Persian cat.

    Science.gov (United States)

    Zimmerman, Kurt; Feldman, Bernard; Robertson, John; Herring, Erin S; Manning, Thomas

    2003-01-01

    A 1-year-old spayed female Persian cat with alopecia and weight loss had numerous variably ulcerated dermal nodules. Cytologic examination of an aspirate of one of the nodules revealed pyogranulomatous inflammation along with septate hyphae and basophilic round bodies, 0.5-1.0 microm in diameter, surrounded by a thin clear halo (arthrospores). The cytologic diagnosis was dermatophytic pseudomycetoma. Histologically, there were dermal granulomas containing poorly staining, septate hyphae with bulbous spores embedded within abundant amorphous eosinophilic material (Splendore-Hoeppli reaction), and the histologic diagnosis was pseudomycetoma-associated chronic multifocal severe granulomatous dermatitis with lymphocytic perifolliculitis and furunculosis. Microsporum canis was cultured from the lesion. Pseudomycetomas are distinguished from fungal mycetomas, or eumycotic mycetomas, by the findings of multiple lesions, lack of a history of skin trauma, an association with dermatophytes, most commonly Microsporum canis, and, histologically, lack of true cement material and a more abundant Splendore-Hoeppli reaction in pseudomycetomas. Additionally, pseudomycetomas differ from dermatophytosis, in which lesions are restricted to epidermal structures. Persian cats have a high incidence of pseudomycetoma formation, suggesting a heritable predisposition. The prognosis is fair with systemic antifungal therapy. When examining cytologic specimens from Persian cats with single or multiple dermal nodules, especially if pyogranulomatous inflammation is present, a diagnosis of pseudomycetoma should be suspected and is warranted if arthrospores and refractile septate hyphae are present.

  7. Hyperactivity and alopecia associated with ingestion of valproic acid in a cat.

    Science.gov (United States)

    Zoran, D L; Boeckh, A; Boothe, D M

    2001-05-15

    A 1-year-old castrated male cat was evaluated because of alopecia of approximately 4 to 5 months' duration as well as hyperactive behavior. It was later determined that the cat was ingesting valproic acid by eating food to which it had been added for daily administration to a child in the household who had cerebral palsy. The clinical signs slowly resolved after the source of valproic acid was removed. This emphasizes the sensitivity of cats to drugs that are commonly used in humans. It was not determined whether the clinical signs that developed in this cat were caused by an adverse reaction or from toxicosis as a result of prolonged hepatic elimination of valproic acid, which requires glucuronide metabolism for disposition. However, the cat recovered completely following removal of the drug and prevention of further exposure. This report emphasizes the importance of obtaining a careful and complete history from the owner regarding an animal and its environment. In the cat of this report, the owner had not considered the impact of the presence of the drug in the child's food.

  8. Predisposing factors for renal scarring in children with urinary tract infection

    Directory of Open Access Journals (Sweden)

    Fatemeh Beiraghdar

    2012-01-01

    Full Text Available This study was undertaken to determine the predisposing factors for renal scarring in children with urinary tract infection. In this prospective cohort study, 176 children with documented urinary tract infection were categorized into four groups: ≤1 year old, 1-2 years old, 2-7 years and 7-14 years old. Ultrasonography and Technetium-99 m-DMSA scan were used to detect the possible abnormalities. Infants under 12 months old presented as the most common group for renal scarring (27 cases, 52.9%, and vesicoureteral reflux (VUR was diagnosed in 29 cases (56.8%. Fifteen (41.67% children between the ages of one and two years had renal scar, and VUR was detected in half of the patients. In the third group, 36.3%, and in fourth group, 41.6% of the patients had renal scar. Also, 38.6% in group three and 50% in the final group had VUR. A co-incidental finding that was observed in this study was the high incidence of pseudohypoaldesteronism (PHA in our patients: in 39.2% of the children in group one, 22.2% in group two and 4% in group three. In group four however, none of the patients had PHA. Risk of scar formation with urinary tract infection (UTI was higher in the younger age group and in those with recurrent UTIs.

  9. The value of TORCH screening in children with bilateral profound sensorineural hearing loss

    Directory of Open Access Journals (Sweden)

    Rabee M Al Sabellha

    2012-01-01

    Full Text Available We aimed to ascertain the effectiveness of TORCH (toxoplasma, rubella, cytomegalovirus, herpes simplex investigation in children with profound sensorineural hearing loss (SNHL. Review of TORCH laboratory results in 2011 from 168 patients who had cochlear implants between 2006 and 2010 at King Abdul-Aziz University hospital Riyadh was conducted. Of the 168 patients, 102 had TORCH laboratory results. Nine were positive for cytomegalovirus (CMV IgM antibody (8.8%, two were positive for herpes simplex virus (HSV IgM antibody (1.96%, and one was positive for rubella IgG (0.9%. No patient showed positive results for toxoplasma or syphilis. The mean age at which the request was made was 5.89 years. All 102 patients who had TORCH laboratory results were above the age of 2 years, and all the patients had bilateral profound SNHL. The nine patients who were positive for CMV were above 1 year old, and it was thus difficult to differentiate between congenital and acquired CMV infection; however, acquired CMV is unlikely to cause a neurodevelopmental disability.

  10. Imaging abusive head trauma: why use both computed tomography and magnetic resonance imaging?

    Energy Technology Data Exchange (ETDEWEB)

    Vazquez, Elida; Delgado, Ignacio; Sanchez-Montanez, Angel [Hospital Universitario Vall d' Hebron, UAB, Pediatric Radiology Department, Barcelona (Spain); Fabrega, Anna [Hospital Universitario Vall d' Hebron, UAB, Department of Pediatrics, Barcelona (Spain); Cano, Paola [Hospital Universitario Vall d' Hebron, UAB, Pediatric Neurosurgery, Barcelona (Spain); Martin, Nieves [Hospital Universitario Vall d' Hebron, UAB, Pediatric Ophthalmology, Barcelona (Spain)

    2014-12-15

    Abusive head trauma is the leading cause of death in child abuse cases. The majority of victims are infants younger than 1 year old, with the average age between 3 and 8 months, although these injuries can be seen in children up to 5 years old. Many victims have a history of previous abuse and the diagnosis is frequently delayed. Neuroimaging is often crucial for establishing the diagnosis of abusive head trauma as it detects occult injury in 37% of cases. Several imaging patterns are considered to be particularly associated with abusive head trauma. The presence of subdural hematoma, especially in multiple locations, such as the interhemispheric region, over the convexity and in the posterior fossa, is significantly associated with abusive head trauma. Although CT is the recommended first-line imaging modality for suspected abusive head trauma, early MRI is increasingly used alongside CT because it provides a better estimation of shear injuries, hypoxic-ischemic insult and the timing of lesions. This article presents a review of the use and clinical indications of the most pertinent neuroimaging modalities for the diagnosis of abusive head trauma, emphasizing the newer and more sensitive techniques that may be useful to better characterize the nature and evolution of the injury. (orig.)

  11. Characteristics of one-year-old shoots of peach hybrids from the crossing combination Flaminia × Hale Tardiva Spadoni

    Directory of Open Access Journals (Sweden)

    Radović Aleksandar R.

    2015-01-01

    Full Text Available The results of two-year research (2011-2012 of the most important morphological characteristics of 1-year-old shoots in eight peach hybrids obtained from a crossing combination Flaminia × Hale Tardiva Spadoni were shown in this paper. The following characteristics were studied in tested hybrids: length and diameter of shoots, internode length, number of flowers and vegetative buds per shoot, ratio of flower to vegetative buds, number of flower buds per node and 1-m length of a shoot. The properties of sylleptic shoots on one-year-old shoots have also been studied. The significant differences were determined among the hybrids for parameters such as the diameter of shoots, internode length, number of flower and vegetative buds per shoot. Hybrids FH1 and FH6 were characterized by the highest density of flower buds, so that they are singled out as potentially the most yielding. These hybrids may be of interest for growing in areas where there is a risk of frost and in the domain of breeding when creating new peach cultivars of high yield potential. [Projekat Ministarstva nauke Republike Srbije, br. TR 31063: Primena novih genotipova i tehnoloških inovacija u cilju unapređenja voćarske i vinogradarske proizvodnje

  12. Cardiomyopathy in captive African hedgehogs (Atelerix albiventris).

    Science.gov (United States)

    Raymond, J T; Garner, M M

    2000-09-01

    From 1994 to 1999, 16 captive African hedgehogs (Atelerix albiventris), from among 42 necropsy cases, were diagnosed with cardiomyopathy. The incidence of cardiomyopathy in this study population was 38%. Fourteen of 16 hedgehogs with cardiomyopathy were males and all hedgehogs were adult (>1 year old). Nine hedgehogs exhibited 1 or more of the following clinical signs before death: heart murmur, lethargy, icterus, moist rales, anorexia, dyspnea, dehydration, and weight loss. The remaining 7 hedgehogs died without premonitory clinical signs. Gross findings were cardiomegaly (6 cases), hepatomegaly (5 cases), pulmonary edema (5 cases), pulmonary congestion (4 cases), hydrothorax (3 cases), pulmonary infarct (1 case), renal infarcts (1 case), ascites (1 case), and 5 cases showed no changes. Histologic lesions were found mainly within the left ventricular myocardium and consisted primarily of myodegeneration, myonecrosis, atrophy, hypertrophy, and disarray of myofibers. All hedgehogs with cardiomyopathy had myocardial fibrosis, myocardial edema, or both. Other common histopathologic findings were acute and chronic passive congestion of the lungs, acute passive congestion of the liver, renal tubular necrosis, vascular thrombosis, splenic extramedullary hematopoiesis, and hepatic lipidosis. This is the first report of cardiomyopathy in African hedgehogs. PMID:11021439

  13. Investigation of regurgitation and other symptoms of gastroesophageal reflux in Indonesian infants

    Institute of Scientific and Technical Information of China (English)

    Badriul Hegar; Aswitha Boediarso; Agus Firmansyah; Yvan Vandenplas

    2004-01-01

    AIM: To evaluate the incidence of regurgitation and other symptoms of gastroesophageal reflux in Indonesian infants.METHODS: In a cross-sectional study at the University Outpatient Clinic for vaccination in Jakarta, 138 mothers of healthy infants less than 12-mo old were prospectively asked to report the frequency of regurgitation.RESULTS: Whatever the age was, some infants did not regurgitate (from 10% during the first month of life to 67%in 1-year-old infants). Regurgitation of at least once a day was reported in 77% of infants younger than 3 mo. Daily regurgitation decreased to 12% in the 9-12 mo old group.Reported peak prevalence was 81%(26/32) during the first month of life. Regurgitation decreased sharply between the 4-6 and 7-9 mo old groups (from 44% to 9%). The longer the regurgitation persisted, the more frequently the mother perceived regurgitation as a problem. Volume and frequency of regurgitation, back arching, irritability, crying and refusal of feeding were the symptoms causing maternal anxiety. The longer the regurgitation persisted, the more frequently the mothers viewed it as a health problem.CONCLUSION: Regurgitation occurs frequently in Indonesian infants, and is a frequent cause of concern to mothers.

  14. Reasoning about instrumental and communicative agency in human infancy.

    Science.gov (United States)

    Gergely, György; Jacob, Pierre

    2012-01-01

    Theoretical rationality and practical rationality are, respectively, properties of an individual's belief system and decision system. While reasoning about instrumental actions complies with practical rationality, understanding communicative actions complies with the principle of relevance. Section 2 reviews the evidence showing that young infants can reason about an agent's instrumental action by representing her subjective motivations and the episodic contents of her epistemic states (including false beliefs). Section 3 reviews the evidence showing special sensitivity in young human infants to some ostensive behavioral signals encoding an agent's communicative intention. We also address the puzzle of imitative learning of novel means actions by 1-year olds and argue that it can be resolved only by assuming that the infant construes the model's demonstration as a communicative, not an instrumental, action. Section 4 reviews the evidence for natural pedagogy, a species-unique social communicative learning mechanism that exploits human infants' receptivity to ostensive-communicative signals and enables infants to acquire kind-wide generalizations from the nonverbal demonstrations of communicative agents. We argue that the essentialist bias that has been shown to be involved in children's concepts of natural kinds also applies to infants' concepts of artifacts. We further examine how natural pedagogy may also boost inductive learning in human infancy.

  15. The effect of plant growth-promoting rhizobacteria on asparagus seedlings and germinating seeds subjected to water stress under greenhouse conditions.

    Science.gov (United States)

    Liddycoat, Scott M; Greenberg, Bruce M; Wolyn, David J

    2009-04-01

    Plant growth-promoting rhizobacteria (PGPR) can have positive effects on vigour and productivity, especially under stress conditions. In asparagus (Asparagus officinalis L.) field culture, seeds are planted in high-density nurseries, and 1-year-old crowns are transplanted to production fields. Performance can be negatively affected by water stress, transplant shock, and disease pressure on wounded roots. PGPR inoculation has the potential to alleviate some of the stresses incurred in the production system. In this study, the effects of PGPR (Pseudomonas spp.) treatment were determined on 3-week-old greenhouse-grown seedlings and germinating seeds of 2 asparagus cultivars. The pots were irrigated to a predetermined level that resulted in optimum growth or the plants were subjected to drought or flooding stress for 8 weeks. The cultivars responded differently to PGPR: single inoculations of seedlings enhanced growth of 'Guelph Millennium' under optimum conditions and 'Jersey Giant' seedlings under drought stress. Seed inoculations with PGPR resulted in a positive response only for 'Guelph Millennium', for which both single or multiple inoculations enhanced plant growth under drought stress. PMID:19396238

  16. The Acute Effects of Upper Extremity Stretching on Throwing Velocity in Baseball Throwers

    Directory of Open Access Journals (Sweden)

    Michael Williams

    2013-01-01

    Full Text Available Purpose. To examine the effects of static and proprioceptive neuromuscular facilitation (PNF stretching of the shoulder internal rotators on throwing velocity. Subjects. 27 male throwers (mean age = 25.1 years old, SD = 2.4 with adequate knowledge of demonstrable throwing mechanics. Study Design. Randomized crossover trial with repeated measures. Methods. Subjects warmed up, threw 10 pitches at their maximum velocity, were randomly assigned to 1 of 3 stretching protocols (static, PNF, or no stretch, and then repeated their 10 pitches. Velocities were recorded after each pitch and average and peak velocities were recorded after each session. Results. Data were analyzed using a repeated measures ANOVA. No significant interaction between stretching and throwing velocity was observed. Main effects for time were not statistically significant. Main effects for the stretching groups were statistically significant. Discussion. Results suggest that stretching of the shoulder internal rotators did not significantly affect throwing velocity immediately after stretching. This may be due to the complexity of the throwing task. Conclusions. Stretching may be included in a thrower's warm-up without any effects on throwing velocity. Further research should be performed using a population with more throwing experience and skill.

  17. A case of interscapular fibrosarcoma in a dwarf rabbit (Oryctolagus cuniculus).

    Science.gov (United States)

    Petterino, Claudio; Modesto, Paola; Strata, Daniela; Vascellari, Marta; Mutinelli, Franco; Ferrari, Angelo; Ratto, Alessandra

    2009-11-01

    A 1-year-old, intact, male dwarf rabbit (Oryctolagus cuniculus) was vaccinated against myxomatosis and rabbit viral hemorrhagic disease in February 1999, and a localized reaction appeared in the same anatomic site within a few days. No regression was observed after subcutaneous antibiotic treatment. The rabbit was kept under observation, and the swelling apparently disappeared in 3 months. The owner then decided to avoid any further subcutaneous drug administration. The referring veterinarian examined the animal on July 2006 for the sudden appearance of a nodular, 4.5 cm x 3.5 cm x 2.0 cm, subcutaneous mass located over the interscapular space. Fine-needle aspiration was performed, and a population of neoplastic spindle cells, rare pleomorphic multinucleated cells, and rare leukocytes were observed. The mass was surgically removed, fixed in 10% neutral buffered formalin, and routinely processed for histologic, histochemical, and immunohistochemical diagnostic investigation. The neoplastic tissue exhibited fascicles composed of malignant spindle-shaped cells with elongated to oval hyperchromatic nuclei and scant cytoplasm. Occasional multinucleated cells were also observed. The neoplastic cells were immunoreactive for vimentin but did not stain for smooth muscle actin, desmin, myoglobin, and cytokeratins (AE1/AE3). Moreover, the histochemical stain for aluminum was positive. The diagnosis was fibrosarcoma based on morphologic and immunohistochemical results. The histologic features of this neoplasm were remarkably similar to feline injection-site sarcoma. PMID:19901300

  18. Primary Mediastinal Large B-Cell Lymphoma during Pregnancy

    Directory of Open Access Journals (Sweden)

    Cesar A. Perez

    2012-01-01

    Full Text Available Non-Hodgkin’s Lymphoma (NHL rarely presents during pregnancy and primary mediastinal large B-cell lymphoma (PMLBCL accounts for approximately 2.5% of patients with NHL. The case of a 22-year-old woman who was diagnosed with Stage IIA PMLBCL during week 13 of her intrauterine pregnancy is described. The staging consisted in computed tomography (CT of the chest and magnetic resonance imaging (MRI of the abdomen and pelvis. She was managed with R-CHOP regimen (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone for a total of six cycles and, because of the early presentation during the second trimester, she received the entire chemotherapy course during the pregnancy. She delivered a healthy baby at 34 weeks of pregnancy and a 18FDG-PET/CT scan demonstrated complete remission after delivery. After 20 months of follow up she remains with no evidence of disease and her 1-year-old son has shown no developmental delays or physical abnormalities. PMLBCL, although an uncommon subgroup of DLBCL, may present during pregnancy and R-CHOP should be considered as one suitable option in this complex scenario.

  19. 不同年龄段人群血清视黄醇结合蛋白浓度差异及参考范围研究%The Difference of the Concentration of Retinol-bonding Protein Among the People of Different Ages and the Reference ranges

    Institute of Scientific and Technical Information of China (English)

    李继刚; 张顺斌; 许峰

    2012-01-01

      Objective To study the difference of the concentration of retinol bonding protein in serum among the people of different ages and the reference ranges. Methods The people to be researched were divided into five groups according to age. A: 0-1 years old; B: 2-10 years old; C: 11-17 years old; D: 18-60 years old; E: 61-80 years old. The concentration of retinol-bonding protein in serum was measured by immune turbidimetry, and the difference among the groups was analyzed by q test and Wilcoxon paired test. Results The concentrations of retinol bonding protein varied from low to high as group A, B, C, D, E, PD组> C组组>B组>C组,P<0.01,各组别参考范围不同.结论随着年龄的增长,血清中视黄醇结合蛋白的浓度逐渐升高,不同年龄段应有不同的参考范围.

  20. Feasibility of perfusion cardiovascular magnetic resonance in paediatric patients

    Directory of Open Access Journals (Sweden)

    Kellenberger Christian

    2009-01-01

    Full Text Available Abstract Aims As coronary artery disease may also occur during childhood in some specific conditions, we sought to assess the feasibility and accuracy of perfusion cardiovascular magnetic resonance (CMR in paediatric patients. Methods and results First-pass perfusion CMR studies were performed under pharmacological stress with adenosine and by using a hybrid echo-planar pulse sequence with slice-selective saturation recovery preparation. Fifty-six perfusion CMR examinations were performed in 47 patients. The median age was 12 years (1 month-18 years, and weight 42.8 kg (2.6-82 kg. General anaesthesia was required in 18 patients. Mean examination time was 67 ± 19 min. Diagnostic image quality was obtained in 54/56 examinations. In 23 cases the acquisition parameters were adapted to patient's size. Perfusion CMR was abnormal in 16 examinations. The perfusion defects affected the territory of the left anterior descending coronary artery in 11, of the right coronary artery in 3, and of the circumflex coronary artery in 2 cases. Compared to coronary angiography, perfusion CMR showed a sensitivity of 87% (CI 52-97% and a specificity of 95% (CI 79-99%. Conclusion In children, perfusion CMR is feasible and accurate. In very young children (less than 1 year old, diagnostic image quality may be limited.

  1. Stress among nurses: an examination of salivary cortisol levels on work and day off

    Directory of Open Access Journals (Sweden)

    Maria Cecilia Pires da Rocha

    2013-10-01

    Full Text Available The present study evaluates the use of salivary cortisol concentration as a physiological index of the stress level among nurses on their work day and day off and correlates it with the questionnaire used to measure occupational stress in nurses (Inventário de Estresse em Enfermeiros - IEE. This is a comparative, cross-sectional descriptive study in which sociodemographic data, IEE results and salivary cortisol levels were used. Fifty-seven nurses participated in the study (80.7% females and a mean age of 37.1 years old. The IEE average score was 124.5. The average cortisol level was 564.1 ng/m on work day and 354.1 ng/mL on day off. Nurses who had double workdays presented high values of salivary cortisol during the work day (638.1 ng/mL. In conclusion, salivary cortisol identified the nurses’ stress level, and differences were found between a work day and day off. On the nurses’ day off, their salivary cortisol levels and stress scores were lower.

  2. Defamilialisation Policies and Attitudes and Behaviour Among Mothers in Twelve European Countries. Do results for Denmark, Finland and Sweden differ from the others?

    Directory of Open Access Journals (Sweden)

    Weckström, Sirpa

    2014-12-01

    Full Text Available Diverse family leave and day care policies create varying monetary incentives for mothers to stay at home with their children. They also affect attitudes of mothers and this should influence childcare decisions. In this study, attitudes of mothers towards cutting down on paid work for the sake of family as well as their behaviour regarding childcare at home were studied in 12 European countries. Of special interest were Denmark, Finland and Sweden, three Nordic countries with a long tradition of childcare policies supporting mothers’ work participation. The data is based on the European Social Survey (ESS Round 2, conducted in 2004 and 2005. The least familialistic attitudes were found in Sweden, Denmark and Finland. A coarse indicator for the effectiveness of childcare policy was devised and indicated that attitudes correlated with the policies in several countries. No correspondence was found between attitudes and average times spent with children at home. Regarding the Nordic countries (particularly Sweden and Finland, the contradictions observed were consistent with childcare policies that affect short- and long-term behaviour in opposite directions. In Finland, a familialistic attitude was relatively common among mothers whose youngest child was under 1-year-old.

  3. Ontogenetic changes in meristic measurements of silver carp and bighead carp.

    Science.gov (United States)

    Yu, Hong-Xia; Tang, Wen-Qiao; Li, Si-Fa

    2010-04-01

    The study analyzed 30 exterior meristic characters for 255 silver and bighead carp samples of 1- to 5-year-old collected from the National Primary Breeding Farm at Laojianghe Lake at the Middle Reach of the Yangtze River. Multivariate analysis was performed. In silver carp, the Euclidean distance was the greatest between the 1-year-old group and other age groups. Silver carp individuals were correctly classified at 98.0% accuracy with a discriminant function established by discriminant analysis based on meristic measurements. Similarly, bighead carp had the greatest distance between 1- to 2-year-old group and other age groups. Individuals of bighead carp were correctly classified at 90.7% accuracy by the discrimination function. The data showed that morphological transformation occurred during the life history of silver and bighead carp development. Eighteen meristic measurements showed highly significant differences, while four showed a significant difference between the two silver carp groups. Ten parameters decreased, while twelve measurements increased during development. In bighead carp, fourteen parameters were significantly different, while three parameters were significantly different between the two groups. Twelve parameters were significantly decreased and another five were increased during development. The results suggest allometric growth should be taken into account when identifying species, analyzing population differences and establishing germplasm standards based on morphology. PMID:20545007

  4. Using heterozygosity-fitness correlations to study inbreeding depression in an isolated population of white-tailed deer founded by few individuals.

    Science.gov (United States)

    Brommer, Jon E; Kekkonen, Jaana; Wikström, Mikael

    2015-01-01

    A heterozygosity-fitness correlations (HFCs) may reflect inbreeding depression, but the extent to which they do so is debated. HFCs are particularly likely to occur after demographic disturbances such as population bottleneck or admixture. We here study HFC in an introduced and isolated ungulate population of white-tailed deer Odocoileus virginianus in Finland founded in 1934 by four individuals. A total of 422 ≥ 1-year-old white-tailed deer were collected in the 2012 hunting season in southern Finland and genotyped for 14 microsatellite loci. We find significant identity disequilibrium as estimated by g 2. Heterozygosity was positively associated with size- and age-corrected body mass, but not with jaw size or (in males) antler score. Because of the relatively high identity disequilibrium, heterozygosity of the marker panel explained 51% of variation in inbreeding. Inbreeding explained approximately 4% of the variation in body mass and is thus a minor, although significant source of variation in body mass in this population. The study of HFC is attractive for game- and conservation-oriented wildlife management because it presents an affordable and readily used approach for genetic monitoring that allowing identification of fitness costs associated with genetic substructuring in what may seem like a homogeneous population. PMID:25691963

  5. Vegetative Growth Characters of the Young Apple Trees Trained in Vertical Axis System

    Institute of Scientific and Technical Information of China (English)

    LI Shao-hua; LI Ming; LIU Guo-jie; MENG Zhao-qing

    2002-01-01

    Vegetative growth of young apple trees trained in vertical axis were studied with ‘Red Fuji',‘Jonagold’, ‘ Orin’ and ‘ Starkrimson’on M7, MM106, M26 interstocks in northern China. About 30branches sprouted from the central leader of the trees during the 4 years after planting for ‘Red Fuji’ and‘Jonagold’, and 26.7 and 20 branches respectively for ‘Orin' and ‘Starkrimson. Moreover the 2-year-old section of the central leader had the strongest capacity to sprout new branches (and sometimes the 1-year-old section too), and sprouted more new shoots than the other section. The total new shoots including spurs on the4-year-old trees reached 631 per tree for ‘ Jonagold', about 480 for ‘ Red Fuji’ and ‘ Orin’, and 312 for‘Starkrimson’. Percentage of spurs was about 61% for ‘Red Fuji’, 73% for ‘Jonagold’ and ‘Orin’, and81% for‘Starkrimson’. Growth vigor of the central leader and limbs of the young apple trees could quickly decline: the growth of the central leader decreased markedly in the fourth year after planting, and branches from the central leader grew vigorously only in the current growth season or in the first two years after branching.

  6. Evaluation of a density-based rapid diagnostic test for sickle cell disease in a clinical setting in Zambia.

    Directory of Open Access Journals (Sweden)

    Ashok A Kumar

    Full Text Available Although simple and low-cost interventions for sickle cell disease (SCD exist in many developing countries, child mortality associated with SCD remains high, in part, because of the lack of access to diagnostic tests for SCD. A density-based test using aqueous multiphase systems (SCD-AMPS is a candidate for a low-cost, point-of-care diagnostic for SCD. In this paper, the field evaluation of SCD-AMPS in a large (n = 505 case-control study in Zambia is described. Of the two variations of the SCD-AMPS used, the best system (SCD-AMPS-2 demonstrated a sensitivity of 86% (82-90% and a specificity of 60% (53-67%. Subsequent analysis identified potential sources of false positives that include clotting, variation between batches of SCD-AMPS, and shipping conditions. Importantly, SCD-AMPS-2 was 84% (62-94% sensitive in detecting SCD in children between 6 months and 1 year old. In addition to an evaluation of performance, an assessment of end-user operability was done with health workers in rural clinics in Zambia. These health workers rated the SCD-AMPS tests to be as simple to use as lateral flow tests for malaria and HIV.

  7. INVESTIGAÇÃO DO USO DE POLIVITAMÍNICOS COMO POSSÍVEL CAUSA DE FLUOROSE EM CRIANÇAS

    Directory of Open Access Journals (Sweden)

    Eliane Gava Pizi

    2009-06-01

    Full Text Available The present study aimed to investigate the causes of fluorosis giving primary focus to the presence of fluoride in polivitaminics. Children had been evaluated with fluorosis by collecting data of the former history as the use of fluorides, the use of vitamin supplements, frequency of toohbrushing and ingestion of fluorinated dentifrices. Interviews were made with parents of 50 children who had fluorosis and 50 without fluorosis. Of the children examined 44% had fluorosis grade 2 (as Index of Dean. Of this total, 88% are natural from Presidente Prudente. According to the report of parents, 56% of children with fluorosis made use of polivitaminics, whereas 18% used Kalyamon B12. According to the intake of fluorinated dentifrices was established that 52% do not ingest dentifricies during toohbrushing and that ingest began after 1 year old. We conclude that the intake of products containing fluoride, the use of fluorinated dentifrices and the fluoride present in drinking water, may be leading to consumption above the recommended, being fundamental importance the supervision and guidance of the use of this to minimize the risk of fluorosis. The use of vitamin supplements containing fluoride is linked to the emergence of fluorosis.

  8. The Interaction of Season Collection of Cuttings, Indol Butyric Acid (IBA and Juvenility Factors on Root Induction in Olea europaea L. Cultivar Kokërr Madhi i Beratit

    Directory of Open Access Journals (Sweden)

    ADHURIM LAZAJ

    2015-03-01

    Full Text Available Differences in the root ability of olive cuttings in the juvenile and mature form are reported. The root ability of cuttings from juvenile and mature olive shoots together with the influence of season stem collection and different concentration of IBA have been studied. The shoots coming from the olive ovule located at the base of the trunk are affected by juvenility factors. Leafy stem cuttings of olive cv. “Kokërr Madhi i Beratit” were obtained from 1-year-old olive shoots sampled on March 25th, April 15th, August 1st and September 1st during the 2013 growing season. The shoots were collected from the olive ovule located at the base of the tree (juvenile form and from canopy of the tree (mature form. To improve the rooting of olive cuttings, different concentrations of IBA, (0,2000,4000, 6000 and 10000 ppm are applied. The percentage of rooted cuttings sampled on March 25t h and April 15th was markedly greater than those sampled on the other seasons (August 1st and September 1st. The concentration 4000 ppm of IBA was most effective. In all the seasons and concentrations of IBA the juvenility modified significantly higher rooting of cuttings.

  9. Intrascrotal lipoblastoma: report of a case and the review of literature.

    Science.gov (United States)

    Yada, Keigo; Ishibashi, Hiroki; Mori, Hiroki; Shimada, Mitsuo

    2016-12-01

    Intrascrotal lipoblastoma is a rare pediatric benign soft tissue neoplasm, and only 11 cases have been reported. The accurate preoperative diagnosis is difficult because of its rarelity and the similarity with the other soft tissue tumors. Among them, accurate preoperative diagnosis had been made in only one case. Thus, almost all of the cases had required inguinal mass excision (and orchidectomy in one case). In this paper, we discuss the accurate preoperative diagnosis of intrascrotal lipoblastoma and subsequent simple tumorectomy via minimal invasive scrotal skin incision, in 1-year-old boy. On physical examination, intrascrotal extra-testicular lobulated mass was palpated on the right scrotum. An ultrasonography revealed the well-circumscribed, iso-echoic, scant blood-flow, and lobulated tumors with each lobules of 1 to 4 cm in diameter, and the tumor located outside of the tunica vaginalis testis. The serum values of alpha-fetoprotein (AFP) and beta-human chorionic gonadotropin (b-hCG) were within normal limit. The preoperative diagnosis of intrascrotal lipoblastoma was made, and the mass was excised via minimal scrotal incision. The right testicle and epididymis were normal. The lesion consisted of the distinct two lobulated tumors, and microscopic examination confirmed the diagnosis of intrascrotal lipoblastoma. The postoperative course was uneventful without evidence of recurrence. A rare intrascrotal lipoblastoma is seldom made accurate preoperative diagnosis; however, the accurate preoperative suspicion of this tumor leads to the minimal invasive tumorectomy via scrotal skin incision and favorable postoperative recovery without recurrence. PMID:27059472

  10. The Effect of Exhausting Exercise Induced Muscular Fatigue On Functional Stability

    Directory of Open Access Journals (Sweden)

    K. Letafatkar

    2009-01-01

    Full Text Available Problem statement: To quantify the effect of exhausting exercise induced muscular fatigue on functional stability. Approach: About 30 male professional athletes with mean age 23±2.1 years old, mean weight 82±1.3 kg and mean height1 81±9.7 cm were selected for participation in this study. In this study Unstable Biodex platform (level 3 used for stability evaluation. Balance performance was quantified as a stability index and the mean deflection of the platform. Running Based Anaerobic Test (RAST test used for fatigue execution. Results: Results showed no significant (p>0.05 main effect for exercise duration in the stability index, suggesting that balance performance was maintained throughout the competition. Hence there wasn’t a significant relationship between lactate acid accumulation and variations of stability indices (r = -0/661, pConclusion: Therefore, the improvement of proprioception in the ankle and knee joint is recommended as a prevention role to the injuries in the abovementioned joints.

  11. Infusion of ATP increases leg oxygen delivery but not oxygen uptake in the initial phase of intense knee-extensor exercise in humans

    DEFF Research Database (Denmark)

    Nyberg, Michael Permin; Christensen, Peter Møller; Mortensen, Stefan Peter;

    2014-01-01

    The present study examined whether an increase in leg blood flow and oxygen delivery at the onset of intense exercise would speed the rate of rise in leg oxygen uptake. Nine healthy men (25 ± 1 years old, mean ± SEM) performed one-leg knee-extensor exercise (62 ± 3 W, 86 ± 3% of incremental test ...... release was lower after 60, 120 and 180 s of exercise with ATP infusion. These results suggest that O2 delivery is not limiting the rise in skeletal muscle oxygen uptake in the initial phase of intense exercise....... peak power) for 4 min during a control setting (CON) and with infusion of ATP into the femoral artery in order to increase blood flow before and during exercise. In the presence of ATP, femoral arterial blood flow and O2 delivery were higher (P ... (femoral arterial blood flow after 10 s, 5.1 ± 0.5 versus 2.7 ± 0.3 l min(-1); after 45 s, 6.0 ± 0.5 versus 4.1 ± 0.4 l min(-1); after 90 s, 6.6 ± 0.6 versus 4.5 ± 0.4 l min(-1); and after 240 s, 7.0 ± 0.6 versus 5.1 ± 0.3 l min(-1) in ATP and CON conditions, respectively). Leg oxygen uptake...

  12. The Change of Stretched Penile Length and Anthropometric Data in Korean Children Aged 0-14 Years: Comparative Study of Last 25 Years.

    Science.gov (United States)

    Park, Sungchan; Chung, Jae Min; Kang, Dong Il; Ryu, Dong Soo; Cho, Won Yeol; Lee, Sang Don

    2016-10-01

    There has been a great improvement in height and weight of Korean children owing to economic development over the last 25 years. This study aimed to evaluate the penile length of Korean children today and to compare it with a previous Korean study reported in 1987. The cross-sectional study was conducted with 909 Korean boys aged 0-14 years who had been brought to outpatient clinics of five tertiary hospitals (Busan, Ulsan, and Changwon) between September 2013 and May 2015. The stretched penile length (SPL) was measured and the testicular size was measured using orchidometry (mL). Student's t-test or Mann-Whitney U test was used to compare the result of our study and the study reported in 1987. SPL of Korean children gradually increased from 4.1 ± 0.8 cm at 0-1 year old to 9.6 ± 3.0 cm at 13-14 years old, the most rapidly during the age of 13. While body weight and testicular size significantly increased from 1987 in most of age groups, there were no significant changes in SPL although there was in some age groups. Height decreased in the infants 6 years old. With the great economic development over the last quarter century in Korea, height, body weight, and testicular size of children significantly increased but there was no significant change in SPL except penile growth pattern. PMID:27550493

  13. Juvenile Osprey Navigation during Trans-Oceanic Migration.

    Directory of Open Access Journals (Sweden)

    Travis W Horton

    Full Text Available To compensate for drift, an animal migrating through air or sea must be able to navigate. Although some species of bird, fish, insect, mammal, and reptile are capable of drift compensation, our understanding of the spatial reference frame, and associated coordinate space, in which these navigational behaviors occur remains limited. Using high resolution satellite-monitored GPS track data, we show that juvenile ospreys (Pandion haliaetus are capable of non-stop constant course movements over open ocean spanning distances in excess of 1500 km despite the perturbing effects of winds and the lack of obvious landmarks. These results are best explained by extreme navigational precision in an exogenous spatio-temporal reference frame, such as positional orientation relative to Earth's magnetic field and pacing relative to an exogenous mechanism of keeping time. Given the age (<1 year-old of these birds and knowledge of their hatching site locations, we were able to transform Enhanced Magnetic Model coordinate locations such that the origin of the magnetic coordinate space corresponded with each bird's nest. Our analyses show that trans-oceanic juvenile osprey movements are consistent with bicoordinate positional orientation in transformed magnetic coordinate or geographic space. Through integration of movement and meteorological data, we propose a new theoretical framework, chord and clock navigation, capable of explaining the precise spatial orientation and temporal pacing performed by juvenile ospreys during their long-distance migrations over open ocean.

  14. Demographic mechanism of a historical bird population collapse reconstructed using museum specimens.

    Science.gov (United States)

    Green, Rhys E

    2008-10-22

    Long-term studies of demographic rates provide clues about the external causes of animal population declines, but systematic monitoring is rarely in place until after the decline has occurred. This study evaluates alternative hypotheses about the demographic mechanisms underlying the historical collapse of corncrake (Crexcrex) populations in Britain and Ireland in the late nineteenth and early twentieth centuries using characteristics of museum specimens. The proportion of adult corncrakes that are 1-year old was estimated from feather characteristics of birds collected before, during and after the population decline and showed a marked transitory reduction during the decline. This pattern would be expected if the decline was caused by a large reduction in the recruitment of young birds to the breeding population and is the opposite of what would be expected if a change in adult survival had caused the decline. These results are consistent with previous suggestions that the corncrake population decline was caused by adverse effects on breeding productivity caused by the mechanization of the harvesting of hay crops.

  15. FEMALE EPISPADIAS: A CASE REPORT AND REVIEW OF THE LITERATURE

    Directory of Open Access Journals (Sweden)

    R. Angotti

    2012-05-01

    Full Text Available Female epispadias without bladder exstrophy is an extremely rare anomaly, occurring in 1 in 480.000 female population. It’s the mildest form of the extrophy-epispadias-complex (EEC, that is the most se- rious form of abdominal midline malformation (incidence of EEC can be estimated at 1 in 10.000 births. It’s imperative to diagnose this ab- normalities at birth, because that's enough a complete local examina- tion and a good patient’s past medical history, when the patient is greater, about congenital urinary incontinence and recurrent urinary tract infection. The early diagnosis, so the early treatment, is very im- portant to reduce the psychological and psychosocial problems and prevent the urinary incontinence, that’s a real problem for the social life of the patient. The pathology can be corrected by surgical recon- struction of bladder neck, urethra and external genitalia. Epispadias surgery is a reconstructive surgery and it has mainly two aims: the correction of the urinary incontinence and the reconstruct of the ex- ternal genitalia with good aesthetic appearance. In this case report we present a 3-years-old girl with isolated female epispadias, who un- derwent just one operation to correct her anomaly. In this patient the epispadias was unrecognized until 1 years-old. We reviewed, also, the Literature about cases of female epispadias that confirmed the rarity of the disease.

  16. Effect of Arbuscular Mycorrhiza on the Drought Tolerance of Poncirus trifoliata Seedlings

    Institute of Scientific and Technical Information of China (English)

    Wu Qiangsheng; Xia Renxue; Hu Zhengjia

    2006-01-01

    The effects of Glomus mosseae colonization on the plant growth and drought tolerance of 1-year-old trifoliate Poncirus trifoliata seedlings in potted culture were studied in natural water stress and rewatering conditions.Results showed that arbuscular mycorrhizal (AM)inoculation significantly improved the height,stem diameter,and fresh weight of P.trifoliata seedlings before natural water stress.By the end of the experiment,the survival percentage of AM-transplanted seedlings was 8%higher than those of non-AM ones.During water stress and rewatering,AM significantly increased the contents of soluble sugars and proteins in leaves,and enhanced the activities of superoxide dismutase (SOD),guaiacol peroxidase (G-POD),and catalase (CAT) in either seedling leaves or roots,which indicated that AM colonization could improve the osmotic adjustment response of P.trifoliata,enhance its defense system,and alleviate oxidative damages to membrane lipids and proteins.These results demonstrated that the drought tolerance of P.trifoliata seedlings was increased by inoculation with AM fungi.The functional mechanism underlying the observation that mycorrhizas increased the host's drought tolerance was closely related to enzymatic and nonenzymatic antioxidant defense systems such as SOD,GPOD,CAT,and soluble protein.

  17. Reasoning about instrumental and communicative agency in human infancy.

    Science.gov (United States)

    Gergely, György; Jacob, Pierre

    2012-01-01

    Theoretical rationality and practical rationality are, respectively, properties of an individual's belief system and decision system. While reasoning about instrumental actions complies with practical rationality, understanding communicative actions complies with the principle of relevance. Section 2 reviews the evidence showing that young infants can reason about an agent's instrumental action by representing her subjective motivations and the episodic contents of her epistemic states (including false beliefs). Section 3 reviews the evidence showing special sensitivity in young human infants to some ostensive behavioral signals encoding an agent's communicative intention. We also address the puzzle of imitative learning of novel means actions by 1-year olds and argue that it can be resolved only by assuming that the infant construes the model's demonstration as a communicative, not an instrumental, action. Section 4 reviews the evidence for natural pedagogy, a species-unique social communicative learning mechanism that exploits human infants' receptivity to ostensive-communicative signals and enables infants to acquire kind-wide generalizations from the nonverbal demonstrations of communicative agents. We argue that the essentialist bias that has been shown to be involved in children's concepts of natural kinds also applies to infants' concepts of artifacts. We further examine how natural pedagogy may also boost inductive learning in human infancy. PMID:23205408

  18. Product estimate of air kerma-area and the air kerma in the input surface of the skin of pediatric patients undergoing chest X-ray

    International Nuclear Information System (INIS)

    The aim of this paper is to evaluate the entrance air kerma (Ka,e) and the product air kerma-area (Pka) for chest examinations performed with pediatric patients in a large public hospital of Recife. For this study 89 examinations of patient with ages from zero to 10 years old were evaluated. The results showed that the mean Ka,e values, for patients of 0-1 years old, 1-5 years old and 5-10 years old, were, respectively, 100 mGy, 120 mGy and 100 mGy. The Pka values for newborn patients range from 11,9 to 58,4 mGy.cm2, for patients with 1 to 5 years old range from 17 to 192 mGy.cm2, and from 30,4 to 136,2 mGy.cm2 for patients with ages from 5 to 10 years old. The differences in the Pka values are due the different dimensions of the radiation field. For the results its possible to conclude that the Pka values are high, in special for patients with ages from 1 to 5 years old, indicating that the collimation of the radiation field is not adequate. (author)

  19. Cinnarizine for Sea Sickness During a Remote Pacific Ocean Rescue Mission.

    Science.gov (United States)

    Lyon, Regan F; Rush, Stephen C; Roland, J Thomas; Jethanamest, Daniel; Schwan, Christopher P; Kharon, Chetan U

    2015-01-01

    Motion sickness can be a limiting factor for sea and air missions. We report the experience of a Pararescue (PJ) team on a Pacific Ocean rescue mission in which motion sickness was prevalent. Cinnarizine, an antagonist of H1-histamine receptors, was used to treat affected PJs. We also report findings of a survey of PJs regarding motion sickness. A family of four on a disabled sailboat 900 miles off the coast of Mexico sent out a distress call because their 1-year-old daughter became severely ill with fever and diarrhea. Four PJs were deployed on a C-130, performed a free-fall parachute insertion into the ocean, and boarded the sailboat. All four PJs experienced onset of motion sickness at some point during the early part of the mission and symptoms persisted through the first 24 hours. Three PJs experienced ongoing nausea, vomiting, dizziness, and sensory imbalances. The captain of the sailboat offered the three sick PJs approximately 18mg of cinnarizine two or three times a day with relief of symptoms and improvement on operational effectiveness. A new, anonymous, voluntary survey of Air National Guard PJs and combat rescue officers revealed that 78.4% of Operators have experienced motion sickness at sea. We discuss the current theories on motion sickness, the effect of motion sickness on operational effectiveness, and research on treatment of motion sickness, including the medication cinnarizine. PMID:26125158

  20. [Improved Response to 5-FU Using Dose Adjustment and Elastomeric Pump Selection Based on Monitoring of the 5-FU Level--A Case Report].

    Science.gov (United States)

    Muneoka, Katsuki; Shirai, Yoshio; Kanda, Junkichi; Sasaki, Masataka; Wakai, Toshifumi; Wakabayashi, Hiroyuki

    2015-10-01

    A 6 1-year-old man with unresectable multiple hepatic metastases after resection of sigmoid colon carcinoma was treated with irinotecan and infused 5-fluorouracil (5-FU) plus Leucovorin (FOLFIRI). Since the levels of tumor markers increased, the 5-FU dose was increased from 2,700 to 3,000 mg/m2 using a Jackson-type pump and an extended infusion time of 53 hours. The blood level of 5-FU was 507 ng/mL 16 hours after starting the infusion. The pump was then changed to a bottle-type pump with the same dose of 3,000 mg/m2. At 16 hours, the 5-FU level was 964.5 ng/mL. The areas under the concentration vs. time curve (AUC mg・h/L)were 21 and 44 mg・h/L for the Jackson- and bottle-type pumps, respectively. Owing to the development of Grade 3 stomatitis and hand-foot syndrome, 5-FU was reduced to 2,700 mg/m2 with a bottle-type pump. The AUC decreased to 27 mg・h/L, but the liver metastases were reduced and the adverse effects subsided to Grade 1. This case shows that individual dose adjustment of 5-FU to the appropriate AUC based on pharmacokinetic monitoring of the blood 5-FU level can improve the response, reduce adverse effects, and have a clinical benefit. PMID:26489552

  1. Health systems and services.

    Science.gov (United States)

    Mukhopadhyay, A

    1992-01-01

    Since 1/6 of the world population lives in India, the health status of Indians significantly affects the global health situation. India is also a country of contrasts with some states having levels of health similar to the best of other developing countries, to other states having levels of health similar to the worst of other developing countries. India's health system is based on centuries of social tradition; however, it wasn't until this century, that it became clear that the health of workers was directly related to production capacity and thus to the national economy. After independence infant/child mortality was 162/1000 for 1 year olds, the maternal mortality rate was 20/1000, and malaria accounted for 1 million deaths out of 100 million cases. Through an integrated approach to prevention and treatment, these figures have dropped 35.2/1000 for infant mortality. Now, there are other problems like the declining sex ration. In 1901 there were 972 girls/1000 boys, by 1991 this figure dropped to 929. Currently 90% of the population knows about their Public Health Centers, but only 31% utilize the formal health care system, of these 9-23% are dissatisfied. PMID:12343654

  2. Vaccine Adverse Events Reported during the First Ten Years (1998–2008 after Introduction in the State of Rondonia, Brazil

    Directory of Open Access Journals (Sweden)

    Mônica P. L. Cunha

    2013-01-01

    Full Text Available Despite good safety records, vaccines given to young children can cause adverse events. We investigated the reported adverse events following immunization (AEFI of vaccines given to children of less than seven years of age during the first ten years (1998 to 2008 in the state of Rondonia, Brazil. We worked with the events related to BCG (Bacillus Calmett-Guérin, HB (hepatitis B, DTwP/Hib (diphtheria-tetanus-pertussis+Hemophillus influenza b, DTP (diphtheria-tetanus-pertussis, MMR (mumps, measles, rubella, and YF (yellow fever vaccines because they were part of the recommended scheme. The number of doses of vaccines given was 3,231,567 with an average of AEFI of 57.2/year during the studied period. DTwP/Hib was responsible for 298 (57.8%, DTP 114 (22.9%, HB 31 (6%, MMR 28 (5.4%, BCG 24 (4.7%, and YF 20 (3.9% of the reported AEFI. The combination of the AEFI for DTwP/Hib vaccines showed the highest number of systemic (61.4% and local events (33.8%. Young children (≤1-year old were more susceptible to AEFI occurring in the 6 hours (54.2% following vaccine uptake. This study suggests significant differences in reactogenicity of vaccines and that despite limitations of the AEFI Brazilian registry system we cannot ignore underreporting and should use the system to expand our understanding of adverse events and effects.

  3. Mortality following snake bite envenomation by Bitis arietans in an HIV positive child: A case report.

    Science.gov (United States)

    Firth, Gregory B; Street, Matthew; Ramguthy, Yammesh; Doedens, Linda

    2016-07-01

    Snake bites occur commonly in the rural areas of South Africa. Hospitals where snake bites are uncommon should always have protocols on standby in the event of such cases presenting. This is the first reported case documenting the effect of human immunodeficiency virus (HIV) on snake bite in South African children.A case report and review of relevant information about the case was undertaken.We present a case of a 1-year-old child referred from a peripheral hospital following a snake bite to the left upper limb with a compartment syndrome and features of cytotoxic envenomation. The patient presented late with a wide area of necrotic skin on the arm requiring extensive debridement. The underlying muscle was not necrotic. Polyvalent antivenom (South African Institute of Medical Research Polyvalent Snakebite Antiserum) administration was delayed by 4 days after the snake bite. The patient was also diagnosed with HIV and a persistent thrombocytopenia possibly due to both HIV infection and the snake bite venom. Lower respiratory tract infections with subsequent overwhelming sepsis ultimately resulted in the child's death.The case highlights the challenge of treating a snake bite in a young child with HIV and the detrimental outcome of delayed treatment. A protocol is essential in the management of snake bites in all hospitals.Level IV, Case report.This case highlights the interaction of snake bite envenomation and HIV infection on thrombocytopenia. PMID:27399076

  4. RESEARCHES REGARDING THE TECHNOLOGICAL PERFORMANCES OF CARP REARING DURING WINTER PERIOD IN THE CONDITIONS OF A RECIRCULATING AQUACULTURE SYSTEM

    Directory of Open Access Journals (Sweden)

    G. STEFAN

    2013-12-01

    Full Text Available The techniques of carp culture are highly diversified, ranging from the extensive production in pond or open water with no fertilization or supplemental feeding to highly intensive systems in concrete tanks or cages. Among the different carp species, common carp is the best species reared in intensive monoculture, the others (Chinese and Indian carps being usually cultivated in polyculture (P. Kestemont, 1995. An experiment was conducted in inside recirculation system conditions to identify the technological performances on carp growth and survival at the Fishing and Aquaculture Department, Galati, during winter period (February, 2007 – March, 2007. The 1-year-old carp (Cyprinus carpio 4792g; 4594 g; 4561 g and 4525 g (total weight grew to 7384g; 7017g; 6924g and 7125 g in 44 days in aquarium 1, 2, 3 and 4, respectively. In all aquariums, the fish appeared healthy and no mortality was observed. Feed conversion efficiencies (FCE had similar values among all aquariums, the highest FCE being found in B4 aquarium with 1, 57 value. Water quality parameters were acceptable range for fish culture. Results show that the carp rearing during winter period in the inside recirculation system is a very good economic solution.

  5. Rapid population increase in an introduced muskox population, West Greenland

    Directory of Open Access Journals (Sweden)

    Carsten Riis Olesen

    1993-10-01

    Full Text Available In 1962 and 1965, 27 (13 and 14 muskox yearlings were translocated from East Greenland (71°N to the Angujaartorfiup Nunaa range in West Greenland (67°N. Angujaartorfiup Nunaa is a 6600 km2 icefree, continental area where caribou are indigenous. The climate is strictly continental with a minimum of precipitation but with abundant vegetation. Aerial surveys in 1990 documented that the muskox population has increased to 2600 heads despite quota-based harvesting since 1988. The annual quota was 200, 300 and 400 for 1988, 1989 and 1990, respectively. Distribution of muskoxen shows a significant preference for low altitude habitats southeast of Kangerlussuaq Airport and around Arnangarnup Qoorua (Paradise valley. Annual population increment averages 30% and the calf crop is around 24% of the population. Yearling recruitment in the population reveals that calf mortality during winter is very limited. About half of the 1-year-old females are served and they eventually give birth to their first calf when they turn 2 years old. With half of the 2-year-old females reproducing, the calf/cow ration ranges between 0.9 and 1.0.

  6. Targeting connexin 43 protects against the progression of experimental chronic kidney disease in mice.

    Science.gov (United States)

    Abed, Ahmed; Toubas, Julie; Kavvadas, Panagiotis; Authier, Florence; Cathelin, Dominique; Alfieri, Carlo; Boffa, Jean-Jacques; Dussaule, Jean-Claude; Chatziantoniou, Christos; Chadjichristos, Christos E

    2014-10-01

    Excessive recruitment of monocytes and progression of fibrosis are hallmarks of chronic kidney disease (CKD). Recently we reported that the expression of connexin 43 (Cx43) was upregulated in the kidney during experimental nephropathy. To investigate the role of Cx43 in the progression of CKD, we interbred RenTg mice, a genetic model of hypertension-induced CKD, with Cx43+/- mice. The renal cortex of 5-month-old RenTgCx43+/- mice showed a marked decrease of cell adhesion markers leading to reduced monocyte infiltration and interstitial renal fibrosis compared with their littermates. In addition, functional and histological parameters such as albuminuria and glomerulosclerosis were ameliorated in RenTgCx43+/- mice. Interestingly, treatment with Cx43 antisense produced remarkable improvement of renal function and structure in 1-year-old RenTg mice. Similar results were found in Cx43+/- or wild-type mice treated with Cx43 antisense after obstructive nephropathy. Furthermore, in these mice, Cx43 antisense attenuated E-cadherin downregulation and phosphorylation of the transcription factor Sp1 by the ERK pathway resulting in decreased transcription of type I collagen gene. Interestingly, Cx43-specific blocking peptide inhibited monocyte adhesion in activated endothelium and profibrotic pathways in tubular cells. Cx43 was highly increased in biopsies of patients with CKD. Thus, Cx43 may represent a new therapeutic target against the progression of CKD.

  7. Determination of essential elements in commercial infant foods by instrumental neutron activation analysis

    Energy Technology Data Exchange (ETDEWEB)

    Vallinoto, Priscila; Maihara, Vera A., E-mail: pvallinoto@ipen.br, E-mail: vmaihara@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2013-07-01

    Eating habits are important determinants of health conditions during childhood. Commercial infant food is an important part of the diet for many babies. As such it is necessary that such food contain sufficient amounts of essential elements. Inadequate complementary feeding is a major cause of high rates of malnutrition throughout the world. Commercial infant food is classified into four different stages: Stages 1 and 2 are adequate for babies older than 6 months, but new flavors and food are introduced in stage 2; Stage 3 is offered to 8 month old babies; Junior Stage is recommended to children over 1 year old. In this study, essential elements: Ca, Cl, Co, Cr, Fe K, Mg, Mn, Na, Se and Zn were determined in commercial infant food samples by Instrumental Neutron Activation Analysis (INAA). Twenty-seven infant food samples were bought in stores around Sao Paulo city during 2011. These samples were freeze-dried and homogenized before analysis. The powdered samples were irradiated in the IEA-R1 nuclear research reactor of IPEN-CNEN/SP. For validation of the methodology, INCT MPH-2 Mixed Polish Herbs and NIST-SRM 1577b Bovine Liver reference materials were analyzed. Most of the concentration results were below the World Health Organization's recommended daily intake for infants from 6 to 12 months old. These low essential element concentration results in commercial infant foods obtained in our study indicate that infants should not only be fed with commercial baby foods. (author)

  8. Expression of genes related to quality of Longissimus dorsi muscle meat in Nellore (Bos indicus) and Canchim (5/8 Bos taurus × 3/8 Bos indicus) cattle.

    Science.gov (United States)

    Giusti, Juliana; Castan, Eduardo; Dal Pai, Maeli; Arrigoni, Mário De Beni; Rodrigues Baldin, Samira; De Oliveira, Henrique Nunes

    2013-06-01

    This study was performed to compare CAPN1, CAPN2, CAST, TG, DGAT1 and LEP gene expressions and correlate them with meat quality traits in two genetic groups (Nellore and Canchim) in order to assess their expression profile and use their expression profile as genetic markers. We analyzed 30 young bulls (1year old), 15 of each genetic group. Samples of the Longissimus dorsi muscle were collected for analysis of: total lipids (TL) and meat tenderness measured as Warner-Bratzler shear force (SF) and myofibrillar fragmentation (MFI) at day of slaughter and 7days of aging. Gene expression profiles were obtained via RT-qPCR. TL and MFI showed differences between breeds, higher MFI in Canchim and higher TL in Nellore. Calpains showed no differential expression between groups, as did DGAT1, TG, and LEP. CAST was expressed more in the Nellore cattle. The only significant within-breed correlation (0.79) between gene expression and meat traits was found for DGAT1 and MFI in Canchim breed. Although the number of animals used in this study was small, the results indicate that the increased expression of CAST in Nellore may reflect tougher meat, but the lack of correlations with the meat traits indicates it is not a promising genetic marker.

  9. Altered cell metabolism in tissues of the knee joint in a rabbit model of Botulinum toxin A-induced quadriceps muscle weakness.

    Science.gov (United States)

    Leumann, A; Longino, D; Fortuna, R; Leonard, T; Vaz, M A; Hart, D A; Herzog, W

    2012-12-01

    Quadriceps muscle weakness is frequently associated with knee injuries in sports. The influence of quadriceps weakness on knee joint homeostasis remains undefined. We hypothesized that quadriceps weakness will lead to tissue-specific alterations in the cell metabolism of tissues of the knee. Quadriceps weakness was induced with repetitive injections of Botulinum toxin A in six 1-year-old New Zealand White rabbits for 6 months. Five additional animals served as controls with injections of saline/dextrose. Muscle weakness was assessed by muscle wet mass, isometric knee extensor torque, and histological morphology analysis. Cell metabolism was assessed for patellar tendon, medial and lateral collateral ligament, and medial and lateral meniscus by measuring the total RNA levels and specific mRNA levels for collagen I, collagen III, MMP-1, MMP-3, MMP-13, TGF-β, biglycan, IL-1, and bFGF by reverse transcription and polymerase chain reaction. While the total RNA levels did not change, tissue-specific mRNA levels were lower for relevant anabolic and catabolic molecules, indicating potential changes in tissue mechanical set points. Quadriceps weakness may lead to adaptations in knee joint tissue cell metabolism by altering a subset of anabolic and catabolic mRNA levels corresponding to a new functional and metabolic set point for the knee that may contribute to the high injury rate of athletes with muscle weakness.

  10. Effects of Cutting Density on Growth,Yield and Quality of Poplar Clone Seedlings

    Institute of Scientific and Technical Information of China (English)

    Fang Shengzuo; Tian Ye; Yuan Fayin

    2006-01-01

    In order to identify the optimum cutting density for producing the highest number of plantable seedlings of poplar clones,a split-plot randomized block design was used to establish four cutting densities in plots.Based on data on the survival,leaf area,seedling height,caliper,and biomass of 1-year-old seedlings of clones Nanlin-95,Nanlin-895,Nanlin-1388 and NL-80351,the growth characteristics and seedling quality under four cutting densities were analyzed.Results indicated that the leaf area,stern and leaf biomass,and caliper of seedlings of all four poplar clones increased with the decrease in cutting density.Leaf area index reached its highest level at the spacing of 40 cm×40 cm,while the aboveground biomass of the seedling on an area basis increased as the cutting density increased.Seedling quality at low cutting density was higher than that at closer cutting density.The quantity of first-grade seedlings (grade Ⅰ) for clones Nanlin-95 and Nanlin-895 was achieved at the spacing of 40 cm×50 cm;for NL-1388 and NL-80351,it was 50 cm×50 cm.According to the seedling quality and the number of plantable seedlings produced,the suggested cutting density for these four poplar clones was 50,000 stems/hm2.

  11. Genetic Test of New Cottonwood Clones at Nursery Stage

    Institute of Scientific and Technical Information of China (English)

    QINGuanghua; JIANGYuezhong

    2004-01-01

    Twenty-five new clones belong to Populus Aigeiros of both domestic and foreign origin had been introduced and tested at nursery stage in Shandong province. Results showed that height (H),diameter at stem base (DO) and survival rate (SR) varied significantly and genetic variation were very large among the clones. CVg and broad-sense heritability (h2) of H, DO and SR of 1-year-old stock nursery were 7.43%, 9.25%, 18.78% and 78.91%, 96.31%, 95.93%, respectively, showing high genetic control on the tested traits. 11 superior clones with characteristics of high growth rate and medium or high SR were primarily selected and genetic gains (△G) of H, DO and SR were 16.89%, 16.08% and 13.08%, respectively.Rooting habits test of some selected clones were also conducted based on the cutting culture in water container and annual growth increment measured. The date of first root emergence, number of main roots, number of lateral roots, length of main roots and the emergence date of growth peak varied to certain degree among the selected clones.

  12. Congenital dislocation of the hip. A review.

    Science.gov (United States)

    Sherk, H H; Pasquariello, P S; Watters, W C

    1981-08-01

    Congenital dislocation of the hip usually results from capsular stretching caused by fetal malposition and crouching late in the third trimester. Early recognition of hip dislocation or instability soon after birth permits prompt treatment. Ortolani's and Barlow's maneuvers, respectively, reduce into and displace from the acetabulum a femoral head that is insecurely contained therein. The diagnosis of CDH in the first month of life usually depends on these clinical components of the physical examination of the newborn, because similar device, in this age group can usually maintain the displaced hip in sufficient flexion and abduction to permit reduction and normal development. By 3 months of age, the nuclei of the pelvis and upper femur have ossified enough to permit radiologic diagnosis of CDH. Problems related to treatment increase as the child grows older. In infants up to 6 months of age, closed methods with a harness usually succeed. Beyond 6 months, the soft tissues shorten and prevent easy reduction. These patients almost always require pre-reduction traction. An adductor tenotomy also facilitates reduction and apparently lessens compressive forces on the femoral head, an important consideration in preventing avascular necrosis of the head. Children over 1 year old develop bony changes, such as excessive femoral valgus and anteversion and deformity of the acetabulum. Treatment in these patients requires realignment of bony deformities with femoral or pelvic osteotomies in addition to the measures noted previously. The gentleness and high success rate of early treatment make early diagnosis of CDH an important consideration in infants and newborns.

  13. Tendência das meningites por Haemophilus influenzae tipo b no Brasil, em menores de 5 anos, no período de 1983 a 2002 Trends in Haemophilus influenzae type b meningitis in Brazil in children under five years of age from 1983 through 2002

    Directory of Open Access Journals (Sweden)

    Sybelle de Souza Castro Miranzi

    2006-10-01

    Full Text Available Trata-se de um estudo ecológico, tipo série histórica (1983-2002, onde foram calculados os coeficientes de incidência, mortalidade e letalidade de meningites por Haemophilus influenzae , tipo b, no Brasil, e avaliou-se a tendência da morbi-mortalidade em menores de 5 anos. Para a análise de tendência dos coeficientes construíram-se modelos de regressão polinomial para as faixas etárias de The study was based on an ecological design using a historical time series (1983-2002, related to Haemophilus influenzae type b meningitis in Brazil. Incidence, mortality and case-fatality rates, as well as trends in incidence and morbidity-mortality were estimated in children less than 5 years of age. Polynomial regression analysis was used to analyze trends, adopting a significance level of 0.05. 43.9% of confirmed cases occurred in infants less than 1 year old and 38.7% in children 1-4 years old. The observed rates were also highest in these two age strata. The incidence and mortality rates showed an increasing trend, until approximately 1999, when a quick decline was observed. The study results reinforce the effectiveness of the Vaccination Program against HIB in Brazil, which benefited age ranges that did not receive the vaccine (Herd Immunity.

  14. Clinical and course indicators of bipolar disorder type I with and without opioid dependence

    Directory of Open Access Journals (Sweden)

    Amir Shabani

    2010-01-01

    Full Text Available Background: The existing evidence about the clinical situations of the bipolar patients with opioid dependence is scarce. The present study was carried out to compare the clinical features and course of the bipolar disorder type I re-garding the two subgroups of opioid dependent and non- dependent. Methods: There were 178 adult patients with bipolar disorder type I consecutively referred to the Iran Hospital of Psy-chiatry, Tehran, Iran, from January 2008 to January 2009 who enrolled in the study. The Persian Structured Clinical Interview for DSM- IV axis I disorders (SCID- I, HDRS- 17, and Y- MRS were administered for all patients. Other clini-cal information was gathered through the face- to- face interviews with the probands and the hospital records. The T test, Chi square test and logistic regression were used to analyze the data. Results: The mean age of probands were 33.6 ± 11.1 years old and they were mostly male. Among the evaluated indi-ces, the factors gender, anxiety disorders comorbidity, non- adherence, and positive family history were different sig-nificantly and independently from the other studied factors between opioid dependent and non- dependent bipolar pa-tients. Conclusions: Despite some differences, the opioid dependent and non- dependent bipolar patients did not have any significant difference regarding most of the examined clinical and course indices.

  15. Influence of solar UV radiation on the nitrogen metabolism in needles of Scots pine (Pinus sylvestris L.)

    Energy Technology Data Exchange (ETDEWEB)

    Krywult, Marek [Department of Instrumental Analysis, Provincial Sanitary-Epidemiological Station, State Sanitary Inspection, Pradnicka 76, PL-31-202 Krakow (Poland)], E-mail: marasek2@gazeta.pl; Smykla, Jerzy [Department of Biodiversity, Institute of Nature Conservation, Polish Academy of Sciences, Mickiewicza 33, PL-31-120 Krakow (Poland)], E-mail: smykla@iop.krakow.pl; Kinnunen, Heli [Finnish Forest Research Institute, Rovaniemi Research Unit, P.O. Box 16, FI-96301 Rovaniemi (Finland)], E-mail: heli.kinnunen@gmail.com; Martz, Francoise [Finnish Forest Research Institute, Rovaniemi Research Unit, P.O. Box 16, FI-96301 Rovaniemi (Finland)], E-mail: francoise.martz@metla.fi; Sutinen, Marja-Liisa [Finnish Forest Research Institute, Rovaniemi Research Unit, P.O. Box 16, FI-96301 Rovaniemi (Finland); Department of Biology, University of Oulu, P.O. Box 3000, FI-90014 (Finland)], E-mail: marja-liisa.sutinen@metla.fi; Lakkala, Kaisa [Arctic Research Centre, Finnish Meteorological Institute (FMI-ARC), Taehtelaentie 62, FI-99600 Sodankylae (Finland)], E-mail: kaisa.lakkala@fmi.fi; Turunen, Minna [Arctic Centre, University of Lapland, POB 122, FI-96101 Rovaniemi (Finland)], E-mail: minna.turunen@ulapland.fi

    2008-12-15

    Needles of 20-year-old Scots pine (Pinus sylvestris L.) saplings were studied in an ultraviolet (UV) exclusion field experiment (from 2000 to 2002) in northern Finland (67 deg. N). The chambers held filters that excluded both UV-B and UV-A, excluded UV-B only, transmitted all UV (control), or lacked filters (ambient). UV-B/UV-A exclusion decreased nitrate reductase (NR) activity of 1-year-old needles of Scots pines compared to the controls. The proportion of free amino acids varied in the range 1.08-1.94% of total proteins, and was significantly higher in needles of saplings grown under UV-B/UV-A exclusion compared to the controls or UV-B exclusion. NR activity correlated with air temperature, indicating a 'chamber effect'. The study showed that both UV irradiance and increasing temperature are significant modulators of nitrogen (N) metabolism in Scots pine needles. - This research presents new information on the responses of N metabolism, particularly nitrate reductase (NR) activity, of Scots pine needles to UV radiation and temperature.

  16. Development of the tree and shrub component and recovery techniques in a burnt pine forest, Castel Fusano, Rome

    Directory of Open Access Journals (Sweden)

    Manetti MC

    2007-01-01

    Full Text Available A five-year study (2000-2005 was established in a part of Castel Fusano (Rome pinewood burned in 2000. The aims of the research were: i to analyse the behaviour of the coenoses after fire; ii to verify the post-fire growth and canopy recovery of the Mediterranean maquis; iii to evaluate natural regeneration of italian stone pine (Pinus pinea L.; iv to verify the effectiveness of italian stone pine plantation in enhancing the establishment of the forest cover. Permanent research plots were established to evaluate features and dynamics of the Mediterranean maquis as well as mortality and development of 1-year-old italian stone pine (ca.500 ha-1 seedlings. Two different plantation systems were applied: blocks of three seedlings at 8x8 m distance; one seedling at 5x5 m distance. After five growing seasons from the fire, only 700 stools ha-1 have resprouted, mainly holm oak (48%, whose only 38% of good vigour. Canopy cover of the broad-leaved species is not enough to assure a quick forest establishment. Combined pine plantation with the maquis species, has given satisfactory results, though the mortality was quite high because of the game damages. The block planting performed better for growth and survival of seedlings. This last plantation system could be a rational choice to assure, in a relative short time, forest recovery and mixed stands characterised by a considerable presence of natural vegetation.

  17. Coping with size: China's efforts pay off.

    Science.gov (United States)

    1994-11-01

    With a population of 1.2 billion people, China is the world's most populous country. With so many people and more than 24 million births per year, China has difficulty ensuring that all of its children have been immunized. Most difficult is keeping track of an increasingly mobile population in the current move toward a market economy. Two immunization targets, set by the Chinese government and supported by the World Health Organization and UNICEF, have been reached. By 1988, immunization programs launched in the 1980s had vaccinated at least 85% of infants under 1 year old in all provinces and regions against tuberculosis, diphtheria, pertussis, tetanus, polio, and measles. By 1990, the same coverage level had been achieved in all of China's urban districts and rural counties, and China is now well on its way to achieving 85% coverage in all townships by the end of 1995. China's coverage against individual diseases is also impressive. The incidence of targeted vaccine-preventable diseases has plummeted, while life expectancy at birth has risen from approximately 64 years in the 1970s to 69 years in 1992 for both sexes combined. Despite reducing its estimated neonatal tetanus (NT) death rate from around 55 deaths/1000 births in 1954 to 4/1000 in 1980, an estimated 98,000 infants still die annually in China due to NT. Education programs and two 1-day immunization campaigns against NT are planned for the southern province of Guizhou.

  18. Defects in myelination, paranode organization and Purkinje cell innervation in the ether lipid-deficient mouse cerebellum.

    Science.gov (United States)

    Teigler, Andre; Komljenovic, Dorde; Draguhn, Andreas; Gorgas, Karin; Just, Wilhelm W

    2009-06-01

    Ether lipids (ELs), particularly plasmalogens, are essential constituents of the mammalian central nervous system. The physiological role of ELs, in vivo, however is still enigmatic. In the present study, we characterized a mouse model carrying a targeted deletion of the peroxisomal dihydroxyacetonephosphate acyltransferase gene that results in the complete lack of ELs. Investigating the cerebellum of these mice, we observed: (i) defects in foliation patterning and delay in precursor granule cell migration, (ii) defects in myelination and concomitant reduction in the level of myelin basic protein, (iii) disturbances in paranode organization by extending the Caspr distribution and disrupting axo-glial septate-like junctions, (iv) impaired innervation of Purkinje cells by both parallel fibers and climbing fibers and (v) formation of axon swellings by the accumulation of inositol-tris-phosphate receptor 1 containing smooth ER-like tubuli. Functionally, conduction velocity of myelinated axons in the corpus callosum was significantly reduced. Most of these phenotypes were already apparent at P20 but still persisted in 1-year-old animals. In summary, these data show that EL deficiency results in severe developmental and lasting structural alterations at the cellular and network level of the cerebellum, and reveal an important role of ELs for proper brain function. Common molecular mechanisms that may underlie these phenotypes are discussed. PMID:19270340

  19. Effect of storage on the chemical composition and biological activity of several popular South African medicinal plants.

    Science.gov (United States)

    Stafford, G I; Jäger, A K; van Staden, J

    2005-02-10

    The in vitro biological activity of nine frequently used medicinal plants in South Africa was assessed and re-assessed after various lengths of storage. The plants investigated were Alepidea amatymbica, Leonotis leonurus, Drimia robusta, Vernonia colorata, Merwilla natalensis, Eucomis autumnalis, Bowiea volubilis, Helichrysum cymosum and Siphonochilus aethiopicus. Water, ethanol and hexane extracts of fresh, 90-day-old and 1-year-old material were assayed for antibacterial activity against four strains of bacteria and for COX-1 inhibition activity. TLC-fingerprints of the fresh and stored extracts were produce to document chemical changes. Alepidea amatymbica, Eucomis autumnalis, Helichrysum cymosum, Leonotis leonurus, Siphonochilus aethiopicus and Vernonia colorata were investigated further as to the effect of 1 year's storage. Elevated temperature and humidity (55 degrees C and 100% relative humidity) were used to accelerate the ageing process of Alepidea amatymbica, Leonotis leonurus and Vernonia colorata plant material for further investigation. The TLC-fingerprints indicated that there was chemical breakdown during storage in certain species. The degree of changes in biological activity and chemistry due to storage were species-specific. In general, antibacterial activity was retained in most species while COX-1 inhibition activity was lost rapidly. PMID:15652284

  20. Sialoblastoma of the cheek: A case report and review of the literature

    Science.gov (United States)

    SITTHICHAIYAKUL, PEERAYUT; SOMRAN, JULINTORN; OILMUNGMOOL, NONGLUK; WORASAKWUTTIPONG, SARAN; LARBCHAROENSUB, NOPPADOL

    2016-01-01

    Sialoblastoma is a rare salivary gland tumor that recapitulates the primitive salivary gland anlage. The authors herein report a case of sialoblastoma of a minor salivary gland, clinically presenting with progressive enlargement of a mass in the cheek of a 1-year-old female infant. Histopathologically, the mass consisted of tight clusters of basaloid cells and partially formed ductal and pseudo-ductal spaces separated by thin fibrous bands. Immunohistchemical studies demonstrated the presence of cytokeratin AE1/AE3, p63, CD99, α-fetoprotein (AFP) and Hep Par-1 expression in a considerable number of tumor cells. The clinical and pathological characteristics are presented and relevant literature is reviewed. Early complete surgical excision is recommended for the treatment of sialoblastoma. Radiation may be considered in cases with incomplete resection of the tumor. Chemotherapy may play a vital role in extensive, metastatic, or relapsed cases, or in cases with inadequate excision. The follow-up treatment should be frequent and prolonged. To the best of our knowledge, this is the first reported case of sialoblastoma of the cheek with immunoreactivity for AFP and Hep Par-1, which may be associated with the embryonic origin of the tumor. AFP may be a useful marker of tumor response in patient with sialoblastoma. PMID:27284424

  1. Comparative study of plant growth of two poplar tree species irrigated with treated wastewater, with particular reference to accumulation of heavy metals (Cd, Pb, As, and Ni).

    Science.gov (United States)

    Houda, Zarati; Bejaoui, Zoubeir; Albouchi, Ali; Gupta, Dharmendra K; Corpas, Francisco J

    2016-02-01

    Water is a scarce natural resource around the world which can hamper the socio-economic development of many countries. The Mediterranean area, especially north Africa, is known for its semi-arid to arid climate, causing serious water supply problems. Treated wastewater (TWW) is being used as an alternative strategy for recycling wastewater. It is also a potential source of nutrients for reforestation with certain plant species such as poplar trees, a useful wood resource, and even for phytoremediation purposes. In the present study, we used treated wastewater to irrigate two clones of 1-year-old poplar trees (Populus nigra cv. I-488 and Populus alba cv. MA-104) for 90 days. After a stipulated time, a comparative study was made of the effects of TWW on growth parameters, acquisition of essential minerals (Na, Fe and Zn) and pollutants (Cd, Pb, As and Ni) as well as the enrichment of secondary metabolites such as polyphenolic, flavonoid and tannin compounds which could contribute to the growth and development of poplar plants. The results of this study show that the use of TWW increased P. alba's biomass production by 36% and also enhanced its Cd and Pb accumulation capacity. We also found that P. alba has considerable potential to be used as an alternative plant species for reforestation and/or phytoremediation of toxic metals from contaminated water or effluent. PMID:26780418

  2. Allogeneic cartilage used for skull base plasty in children with primary intranasal encephalomeningocele associated with cerebrospinal fluid rhinorrhea.

    Science.gov (United States)

    Parízek, J; Mĕrićka, P; Nĕmecek, S; Nĕmecková, J; Zemánková, M; Sercl, M; Häringová, M

    1996-03-01

    Three children with primary intranasal encephalomeningocele associated with cerebrospinal fluid rhinorrhea were operated on at the Department of Neurosurgery, Hradec Králové. In two children, aged 4 and 9.5 years, freeze-dried allogeneic costal cartilage was glued into the skull base defect. This plugging was covered up with deep frozen allogeneic fascia lata. In the third child, an only 1-year-old boy, after transection of the neck of the encephalomeningocele freeze-dried allogeneic dura mater was glued on extradurally and deep-frozen allogeneic fascia lata applied intradurally. The cerebrospinal fluid rhinorrhea ceased immediately after surgery. Spontaneous atrophy of the intranasal portion of the encephalomeningocele was demonstrated respectively 11, 1, and 7 years postoperatively on computed tomography. To evaluate cartilage healing histologically, the extracted allogeneic cartilage used for orbital roof plasty after 4 months was examined. The extent of spotty regressions represented about 7% of the tissue volume. It is stressed that, once diagnosed, intranasal encephalomeningocele associated with cerebrospinal fluid rhinorrhea should be operated on for prevention of meningitis as soon as possible. PMID:8697455

  3. Evaluation of cortical plasticity in children with cerebral palsy undergoing constraint-induced movement therapy based on functional near-infrared spectroscopy

    Science.gov (United States)

    Cao, Jianwei; Khan, Bilal; Hervey, Nathan; Tian, Fenghua; Delgado, Mauricio R.; Clegg, Nancy J.; Smith, Linsley; Roberts, Heather; Tulchin-Francis, Kirsten; Shierk, Angela; Shagman, Laura; MacFarlane, Duncan; Liu, Hanli; Alexandrakis, George

    2015-04-01

    Sensorimotor cortex plasticity induced by constraint-induced movement therapy (CIMT) in six children (10.2±2.1 years old) with hemiplegic cerebral palsy was assessed by functional near-infrared spectroscopy (fNIRS). The activation laterality index and time-to-peak/duration during a finger-tapping task and the resting-state functional connectivity were quantified before, immediately after, and 6 months after CIMT. These fNIRS-based metrics were used to help explain changes in clinical scores of manual performance obtained concurrently with imaging time points. Five age-matched healthy children (9.8±1.3 years old) were also imaged to provide comparative activation metrics for normal controls. Interestingly, the activation time-to-peak/duration for all sensorimotor centers displayed significant normalization immediately after CIMT that persisted 6 months later. In contrast to this improved localized activation response, the laterality index and resting-state connectivity metrics that depended on communication between sensorimotor centers improved immediately after CIMT, but relapsed 6 months later. In addition, for the subjects measured in this work, there was either a trade-off between improving unimanual versus bimanual performance when sensorimotor activation patterns normalized after CIMT, or an improvement occurred in both unimanual and bimanual performance but at the cost of very abnormal plastic changes in sensorimotor activity.

  4. Radiation doses from coal-fired plants in Oxfordshire and Berkshire

    International Nuclear Information System (INIS)

    This report contains an assessment of the radiation doses to members of the public living in Oxfordshire and Berkshire from the releases to atmosphere of natural radioactivity from Didcot Power Station and the coal-fired boilers that operate at the Atomic Weapons Establishment (AWE) at Aldermaston and the Harwell Laboratory of UKAEA. The calculated annual effective dose equivalents to adults from the emissions from Didcot Power Station and the coal-fired plants at AWE, Aldermaston, and UKAEA, Harwell, at 5 km from the sites are, respectively, 0.3, 0.06 and 0.01 μSv. The dose to red bone marrow are broadly comparable with these values. The doses to the other age groups considered (1-year-old and 10-year-old children) are similar to those to the adults. The conclusion is therefore drawn that the discharges from the coal-fired plants make a negligible contribution to the total radiation doses received by the population living around the sites. (author)

  5. Comparative study of electrolyte additives using electrochemical impedance spectroscopy on symmetric cells

    Science.gov (United States)

    Petibon, R.; Sinha, N. N.; Burns, J. C.; Aiken, C. P.; Ye, Hui; VanElzen, Collette M.; Jain, Gaurav; Trussler, S.; Dahn, J. R.

    2014-04-01

    The effect of various electrolyte additives and additive combinations added to a 1 M LiPF6 EC:EMC electrolyte on the positive and negative electrodes surface of 1 year old wound LiCoO2/graphite cells and Li[Ni0.4Mn0.4Co0.2])O2/graphite cells was studied using electrochemical impedance spectroscopy (EIS) on symmetric cells. The additives tested were: vinylene carbonate (VC), trimethoxyboroxine (TMOBX), fluoroethylene carbonate (FEC), lithium bis(trifluoromethanesulfonyl)imide (LiTFSI), and H2O alone or in combination. In general, compared to control electrolyte, the additives tested reduced the impedance of the positive electrode and increased the impedance of the negative electrode with the exception of LiTFSI in Li[Ni0.4Mn0.4Co0.2]O2/graphite wound cells. Higher charge voltage led to higher positive electrode impedance, with the exception of 2%VC + 2% FEC, and 2% LiTFSI. In some cases, some additives when mixed with another controlled the formation of the SEI at one electrode, and shared the formation of the SEI at one electrode when mixed with a different additive.

  6. Mortality rate in children caused by traffic accidents according to geographical regions : Brazil, 1997 - 2005 Mortalidade de crianças por acidente de trânsito segundo região geográfica : Brasil, 1997 a 2005

    Directory of Open Access Journals (Sweden)

    Maria Loffredo

    2012-06-01

    Full Text Available Fatal injuries in children caused by motor vehicle accidents represent a common situation in many countries worldwide. The present study addresses the mortality rate in children as vehicle passengers in Brazil, from 1997 to 2005. To evaluate mortality rates, the number of deaths was collected from the National Mortality Information System (SIM and the population size was obtained using the Brazilian Bureau Census (IBGE data available at DATASUS. Mortality rates were estimated in three-year periods and analyzed according to age groups (younger than 1 year old, 1-4 years old, 5-9 years old and geographical regions using a 95% confidence interval. Overall results showed mortality rates of 5.68, 7.32 and 6.78 (per 1,000,000 for the 1997-1999, 2000-2002 and 2003-2005 periods, respectively for the whole country. Children younger than 1 year old had a mortality rate of 10.18 (per 1,000,000, which was higher than for the other age groups. For the period analyzed, the highest rates were observed for the Mid-West and South regions of Brazil, with rates of 13.88 and 11.47 (per 1,000,000, respectively. These results show the risk of fatal injury in children caused by motor vehicle accidents and may contribute to the establishment of educational campaigns aiming injury prevention in children as vehicle passengers.Lesões fatais em crianças causadas por acidentes de trânsito representam um problema em muitos países. Este estudo analisou a taxa de mortalidade em crianças passageiras de automóveis menores de 10 anos de idade no Brasil, entre 1997 e 2005. Para isso, o número de mortes foi obtido diretamente no banco de dados do Sistema de Informação sobre Mortalidade (SIM e os dados da população são projeções intercensitárias a partir censo demográfico do Instituto Brasileiro de Geografia e Estatística (IBGE disponíveis pelo site do DATASUS. Foram calculadas, para os triênios compreendidos no período em estudo, as taxas de mortalidade por

  7. 2010年夏季急性细菌感染性腹泻患儿沙门菌感染分析%Analysis of Salmonella infection in children with acute bacterial diarrhea in 2010 summer

    Institute of Scientific and Technical Information of China (English)

    王爱敏; 何磊燕; 许学斌; 宋建明; 薛建昌; 王传清

    2011-01-01

    The current report aims to investigate the prevalence and resistance patterns of Salmonella in children with acute bacterial diarrhea. A total of 1045 stool specimens were collected from outpatients and inpatients with acute bacterial diarrhea admitted to Children's Hospital, Fudan University, from 1 July to 30 September in 2010. Salmonella spp. Was identified by culture isolation method. Antimicrobial susceptibility was tested via the Kirby-Bauer method. Salmonella was found in 160 specimens. The total infection rate was 15.3% (160/1045). The infection rate was 23. 6% (119/505) in children under 1-year old, which was significant higher than those in children aged 1 to 5 years (7. 6%, 32/423) and older (7.7%, 9/117) (x2 =2 090, P<0. 001). Twenty-one serotypes of Salmonella were found. Salmonella typhimurium accounted for 40.6% (65/160), Salmonella enteritidis accounted for 25.0% (40/160), and the others accounted for 34.4% (55/160). The resistance rates of Salmonella typhimurium and Salmonella enteritidis to ampicillin were 91. 4% and 69. 0%, to ceftriaxone 29. 3% and 6. 9%, and to cefotaxime 29.3% and 6.9%, respectively. The sensitivity rates of Salmonella typhimurium and Salmonella enteritidis to cefmetazole and fosfomycin were above 90%. These results suggest that Salmonella was the dominant pathogenic bacterium associated with acute bacterial diarrhea in children in our hospital in 2010 summer.The children under 1-year old were more susceptible to Salmonella infection. The prevalence serotypes were Salmonella typhimurium and Salmonella enteritidis and we found that they exhibited varying resistance to the third-generation cephalosporin.%本文旨在了解急性细菌感染性腹泻患儿中沙门菌的感染现状及其耐药性.采集2010年7月1日~2010年9月30日复旦大学附属儿科医院门诊及住院急性细菌感染性腹泻患儿的粪便标本,进行沙门菌分离、培养及鉴定,采用Kirby-Bauer法进行药敏试验.共收集急性细菌

  8. 母株年龄和生长调节剂对俄罗斯大果沙棘嫩枝扦插生根的影响%Effects of donor tree ages and plant growth regulators on the softwood cutting propagation of Hippophae rhamnoides

    Institute of Scientific and Technical Information of China (English)

    杨立学; 王海南; 范晶

    2011-01-01

    研究了母株年龄、植物生长调节剂与其浓度对俄罗斯大果沙棘嫩枝扦插生根效果的影响。结果表明:所有因素对插穗生根率、生根数与平均根长均影响极显著(P〈0.01);母株年龄为1年生插穗的生根效果好于2年生,植物生长调节剂NAA优于IBA与ABT2,植物生长调节剂的浓度以200mg/L为最佳。使用200mg/L的NAA处理1年生大果沙棘的嫩枝插穗30min可以达到最优的生根效果,生根率、生根数与平均根长分别为88.87%、10.8条/穗和10.47cm。同时,因素之间的交互效应对大果沙棘的嫩枝扦插生根具有显著影响,母株年龄与植物生长调节剂的交互效应显著影响大果沙棘扦插的生根率,植物生长调节剂种类与浓度、母株年龄与植物生长调节剂浓度的交互效应对大果沙棘扦插的生根率、生根数与平均根长均具有极显著影响。母株年龄与植物生长调节剂与浓度的交互效应对生根率具有极显著影响。%The rooting effects of donor plant age,plant growth regulators and their concentrations on stem cuttings from Russian seabuckthorn were investigated.The factors mentioned above were highly significant(P0.01) for all studied parameters and the rooting effects of stem cuttings form 1-year-old donor tree were better than from 2-year-old one.NAA was more effective than IBA and ABT2among plant growth regulators and the 200 mg/L concentration of plant growth regulator was the best.Overall,applying 200 mg/L concentration of NAA to treat 1-year-old donor tree cuttings for 30 min could achieve the best rooting,with the rooting rate,root number and average root length being 88.87%,10.8 item/panicle and 10.47 cm,respectivly.Meanwhile,the interaction among the factors also had significant effects on rooting of softwood cuttings.The interactive effects of donor age×plant growth regulators were significant for percent rooting.The interactive effects of plant growth regulators

  9. Tree growth, biomass, allometry and nutrient distribution in Gmelina arborea stands grown in red lateritic soils of Central India

    Energy Technology Data Exchange (ETDEWEB)

    Swamy, S.L.; Kushwaha, S.K.; Puri, S. [Indira Gandhi Agricultural Univ., Raipur (India). Dept. of Forestry

    2004-04-01

    A chronosequence of Gmelina arborea Roxb. stands ranging from 1 to 6 years old was measured to document changes in growth, biomass and nutrient (N, P and K) contents for three red lateritic sites in Chhattisgarh, India. The stand's density, survival and growth parameters (DBH, total height, crown diameter and number of branches) varied significantly with age and site. The number of stems was highest (789 trees/ha) in a 1-year-old plantation at site 3 (Kusumi) and lowest (724 trees/ha) in a 6-year-old stand at site 2 (Anandgoan). Allometric equations for stem wood, branches, leaves and roots to tree diameter at breast height were developed to estimate above ground and below ground tree biomass. The total biomass ranged from 3.9 Mg ha{sup -1} in 1-year-old to 53.7 Mg ha{sup -1} in 6-year-old stand. The stem wood contributed from 55.3% (site 3) to 56.3% (site 1), branch wood from 18.3% (site 2) to 19.8% (site 3), roots from 17.9% (site 3) to 18.5% (site 2) and foliage from 6.6% (site 2) to 7.0% (site 3) of the total biomass. The growth and biomass production were poor from establishment to 3 years age and it increased by 1.5-2 times as the plantation aged from 4-6 years. Nutrient accumulation in tree biomass increased with stand age, following the pattern of biomass accumulation. The total nitrogen accumulation in 6-year-old stands at three sites ranged from 212.9 to 279.5 kg ha{sup -1} with a mean annual storage of 238.4 kg ha{sup -1} and total K ranged from 170.8 to 220.5 kg ha{sup -1} with a mean annual storage of 189.9 kg ha{sup -1} Phosphorous storage was lowest which ranged from 15.0 to 19.6 kg ha{sup -1} with a mean storage of 16.8 kg ha{sup -1} The organic matter and nutrients in the soils improved significantly after 6 years of planting. Available N enhanced by 14.9%, 12.0% and 11.3%, K by 10.0%, 9.1% and 10.6%, whereas phosphorous declined by 2.6%, 23.0% and 20.0%, respectively, at soil depths of 0-20, 21-40 and 41-60 cm. The paper discusses the

  10. 2010年玉溪市华宁县人群麻疹抗体水平调查%Investigation on measles antibody level in Huaning county of Yuxi city in 2010

    Institute of Scientific and Technical Information of China (English)

    普天贵; 向阳武; 余庆福; 向焱

    2012-01-01

    目的 了解华宁县人群实施麻疹疫苗按种情况及血清抗体水平,为2012年按期实现消除麻疹提供依据.方法 采用分层和整群抽样(PPS)方法,在华宁县范围内随机抽取3个乡镇,每个乡镇抽3个行政村,每个村按8个年龄组(<1岁、1岁~、3岁~、5岁~、7岁~、11岁~、15岁~、≥20岁)进行,每个年龄组调查5或6人,共调查382人.结果 调查的382人中麻疹疫苗接种率(≥1针次)为72.51%,抗体阳性率为95.03%;3个乡镇的人群麻疹疫苗接种率、抗体阳性率差异均有统计学意义(P<0.05);各年龄组间麻疹疫苗接种率、抗体阳性率差异有统计学意义(P<0.01),其中<1岁人群的麻疹疫苗接种率、抗体阳性率均较低,分别为44.44%、77.78%;性别间麻疹疫苗接种率、抗体阳性率差异有统计学意义(P<0.05),男性显著高于女性.结论 华宁县人群麻疹抗体阳性率较高,能有效控制输入性病例引起的流行,对有效控制麻疹取得了较好的效果.%[Objective]To study the implementation status of measles vaccination and serum antibody levels in Huaning county, provide the data for measles elimination with a target date of 2012. [Methods] With stratified cluster sampling, 3 townships were randomly sampled from Huaning county, and 3 villages were sampled from each township. There were 8 age groups (under 1 year old, l-3years old, 3-5 years old, 5-7 years old, 7-11 years old, 11-15 years old, 15-20 years old and over 20 years old) , 5 or 6 people were involved into each age groups of each village, and total of 382 people were investigated. [Results] Among 382 people, the immunization coverage rate of measles vaccination (at least one dose-time) was 72. 51% , and the antibody positive rate was 95.03%. There were significant differences in the immunization coverage rate of measles vaccination and the antibody positive rate among 3 townships (P < 0.05). The differences in the immunization

  11. Value research of ultrasonicbone densitometry for early diagnosis of infantile rickets%超声骨密度测定对婴幼儿佝偻病早期诊断的价值研究

    Institute of Scientific and Technical Information of China (English)

    肖厚兰; 陈振华; 梁伟; 罗玲云

    2015-01-01

    目的:研究超声骨密度测定对婴幼儿佝偻病早期诊断的价值。方法全体0~3岁佝偻病患儿中,随机抽取50例0~1岁患儿纳入观察A组,抽取50例1~2岁患儿纳入观察B组,抽取50例2~3岁患儿纳入观察C组;从同期在本科门诊就诊的全体健康检查正常的婴幼儿中随机抽取50例0~1岁婴幼儿纳入对照A组,抽取50例1~2岁婴幼儿纳入对照B组,抽取50例2~3岁婴幼儿纳入对照C组。比较各年龄段观察组和对照组婴幼儿的超声骨密度测定值和观察组内男、女患儿的超声骨密度测定值以评价其早期诊断价值。结果观察A、B、C组患儿超声骨密度测定Z值明显低于对照A、B、C组,差异有统计学意义(P0.05)。结论超声骨密度测定仪对婴幼儿维生素D缺乏性佝偻病具有良好的诊断效果,值得在临床推广应用。%Objective To research the early diagnostic value of ultrasonic bone densitometry for infantile rickets.Methods Among all the 0~3-year-old children with rickets, there were 50 children aging 0~1 year old randomly taken into observation A group, 50 children aging 1~2 year old into observation B group, and 50 children aging 2~3 years old into observation C group. Random selection was also made among healthy children at the same period, and 50 of them aging 0~1 year old were divided into control A group, 50 children aging 1~2 years old were into control B group, and 50 children aging 2~3 years old were into control C group. Comparisons were made on measured values of ultrasonic bone densitometry in every group and different values in different gender, so as to evaluate its value for early diagnosis.Results The observation A, B and C groups had obviously lower Z value of ultrasonic bone densitometry than control A, B and C groups, and the difference had statistical significance (P0.05).Conclusion Ultrasonic bone densitometry can provide good diagnostic effect for infantile vitamin D deficiency rickets

  12. 银川市某医院体检人群EV71型和ECHO病毒感染率的调查%Asymptomatic Infection of Enterovirus 71 and Echovirus in Examination Population of Yinchuan

    Institute of Scientific and Technical Information of China (English)

    白永生; 杨安宁; 张静; 孙炜炜; 王菊; 郭爱玲

    2012-01-01

    目的 了解银川市不同年龄组人群肠道病毒71型(EV71型)和埃克病毒(ECHO)感染率情况及IgG抗体阳性率分布情况.方法 采集宁夏银川市某医院204份不同年龄组体检人群血清,用间接酶联免疫吸附试验(ELISA)检测血清中的EV71型和ECHO IgG抗体.结果 204例受检人群血清中EV71型和ECHO IgG阳性率分别为32.4%和15.1%,其中1岁以内婴幼儿EV71抗体阳性率低,1岁~组EV71 IgG抗体阳性率最高达48.3%,但与其他组比较差异无统计学意义.1岁以内婴幼儿ECHO抗体阳性率低,随着年龄增长,抗体阳性率增高,15~65岁组ECHO IgG抗体阳性率最高,为22.3%,与其他组比较差异无统计学意义.结论 普通人群中可能存在EV71型和ECHO隐性感染者,成人EV71隐性感染率较低,儿童是EV71的主要感染者,15岁以下儿童为ECHO感染的高危人群,人群通过自然感染获得免疫保护.%Objective To investigate the serum level and distribution of IgG antibody against Enterovirus 71 ( EV71) and Echovirus ( Echo) in population of Yinchuan. Methods 204 serum samples were collected from examination population in Yinchuan. The IgG antiody to EV71 and Echo was detected by indirect enzyme -linked immunosorbent assay (ELISA). Results The positive rate of EV71 and Echo antibody were respectively 32. 4% and 15. 1% . The positive rate of IgG antibody to EV71 was the lowest under 1 year old,it was the highest in 1 ~5 year group. The positive rate of IgG antibody to Echovirus was the lowest under 1 year old (9.7% ) ,with the age growth, the positive rate increased, and it was highest above 15 years old (22. 3% ). There was no significant difference in positive rate of EV71and Echo antibody among the different age groups. Conclusion There were asymptomatic infections of EV71and Echo in population of Yinchuan. Population acquired EV71 and Echo virus of immunity through recessive infection. The recessive infection of EV71 was low in adults,while the children were

  13. Effect of age on click-evoked otoacoustic emission A systematic review

    Institute of Scientific and Technical Information of China (English)

    Jinfeng Liu; Ningyu Wang

    2012-01-01

    OBJECTIVE: The aims of this study were to investigate the changes of the total intensity of transient evoked otoacoustic emission (TEOAE) and signal-to-noise ratio in various frequency bands as a function of aging, and to explore the role of age-related decline of cochlear outer hair cells.DATA SELECTION: Inclusion criteria: (1) Articles should involve the total TEOAE level or sig-nal-to-noise ratio. (2) The measurement and analysis system used was Otodynamics ILO analysis system (ILO88, ILO92, ILO96 or ILO292). (3) Studies involved groups of greater than 10 subjects and TEOAE results were from normally hearing ears. (4) If more papers from the same author or laboratory analyzed the same subjects, only one was used. MAIN OUTCOME MEASURES: The correlations of the age scale with the total level and sig-nal-to-noise ratio of TEOAE was determined, respectively.RESULTS: (1) TEOAE total level gradually increased until 2 months of age, and then decreased with increasing age. Significant negative correlations between total TEOAE level and age were found (r = -0.885, P = 0.000). (2) The most rapid decrease of TEOAE amplitude occurred at 1 year old. The total TEOAE level decreased about 4.25 dB SPL between 2 months to 1 year old, then about 0.26-0.52 dB SPL from 1 year to 10 years old, about 0.23 dB SPL from 11 years to 25 years old, and about 0.14 dB SPL from 26 years to 60 years old. (3) The signal-to-noise ratio in the fre-quency bands centered at 1.5, 2, 3 and 4 kHz decreased with increasing age after 2 months of age. Significant negative correlations between the signal-to-noise ratio and age were found for frequency bands ranging from 1.5 kHz to 4 kHz, with the highest correlations at 4 kHz (r = -0.890, P < 0.01), then at 3 kHz (r = -0.889, P < 0.01), at 2 kHz (r = -0.850, P < 0.01) and at 1.5 kHz (r = -0.705, P < 0.05). Conversely, a positive correlation between the signal-to-noise ratio centered at 1 kHz and age was found, but was not statistically significant (r = 0

  14. Analysis of success rate of hepatitis B vaccination for children under age of 7 in some district of Shenzhen%深圳某区7岁以下儿童乙肝疫苗免疫成功率现状分析

    Institute of Scientific and Technical Information of China (English)

    许春涛; 宋柯瑶; 杨彩轩

    2015-01-01

    Objective To improve the success rate of hepatitis B vaccination and prevent children who received hepatitis B vaccination from infection of hepatitis B virus ,thereby reducing hepatitis B prevalence ,through hepatitis B vaccine analysis and evaluation of children under age of 7 who received hepatitis B vaccination in a district of Shenz‐hen .Methods Total 1903 children who made health examination per the hospital′s procedure "4‐2‐1" in period of August 2012 to July 2015 were studied ,with collection of finger tip whole blood detection (latex method) to measure hepatitis B surface antibody (HBsAb) ,to analyze HBsAb positive level by age classification of < 1 year old ,1 to 2 yeard old ,2 to 3 years old ,3 to 4 years old ,4 to 5 years old ,5 to 6 years old and 6 to 7 years old .Results Child HB‐sAb positive rate was 45 .19% in that district of Shenzhen ,of which HBsAb positive rate was higher for those chil‐dren under 1 year old ,and it was 62 .39% .The lowest HBsAb rate was 33 .33% for children′s age between 4 and 5 years old .Conclusion In that district of Shenzhen ,children under 7 years old whose HBsAb positive rate was less than the average data of 2006 national hepatitis B serum epidemiology survey ,children′s resistance to HBV was rela‐tively weak ,and need further investigation to find out reasons .%目的:旨在对深圳某区7岁以下儿童接种乙肝疫苗后免疫成功率的现状做分析与评价,以期能够提高儿童乙肝疫苗免疫成功率,避免接种过乙肝疫苗的儿童感染乙肝,从而降低乙肝患病率。方法对2012年8月至2015年7月在本院按照“4‐2‐1”做儿童健康体检的1903名儿童按<1岁、1~2岁、2~3岁、3~4岁、4~5岁、5~6岁、6~7岁进行分组,采集其采用手指末梢全血检测(乳胶法)测所测乙肝表面抗体(HBsAb)阳性水平数据进行分析。结果深圳市某区儿童 HBsAb 阳性率为45.19%,其中<1岁 HBsAb

  15. Survey on measles vaccination rate and measles antibody level in population in Luliang county of Yunnan province, 2010%2010年云南省陆良县人群麻疹接种率调查及抗体水平监测

    Institute of Scientific and Technical Information of China (English)

    资素琼; 赵文强

    2011-01-01

    Objective To evaluate the performance of measles vaccination and understand the measles antibody level in the population in Luliang. Methods Nine vaccination clinics in 3 townships (Zhongshu, Zhaokua and Majie) were selected by stratified and cluster samplings to conduct survey. Results Totally 390 people were surveyed. the overall measles vaccination rate was 94.10% . the serum antibody positive rate was 99.23% . The measles vaccination rate was 96.83% in Zhongshu, 93.85% in Zhaokua and 91.79% in Majie. The measles vaccination rate in age groups were as follows:71.74% in age group of <1 year old, 100% in age group of l -2 years old, 100% in age group of 3 -4 years old, 100% in age group of 5 -6 years old, 98% in age group of 7 -10 years old, 100% in age group of 11 -14 years old, 89.58% in age group of 15 -19 years old and 91.49% in age group of ≥20 years old. and the serum antibody positive rate was 95.65% in age group of <1 year old, 100% in age group of 1 -2 years old, lOO% in age group of 3 -4 years old, 100% in age group of 5 -6 years old, 98% in age group of 7 -10 years old, 100% in age group of 11 - 14 years old, lOO% in age group of 15 -19 years old and lOO% in age group of ≥20 years old. Conclusion The measles vaccination rate in Zhaokua and Majie should be increased to meet the requirement of > 95% in national immunization program. The serum antibody positive rates of measles in all age groups were >95% (indicating that the herd immunity had been formed) , which would facilitate the measles control and elimination.%目的 为客观评价云南省陆良县麻疹疫苗常规免疫接种情况和掌握人群免疫水平.方法 采取分层和整群抽样(PPS)方法抽取调查单位和调查点.全县共确定3个调查单位(中枢镇、召夸镇、马街镇),9个村级接种点为调查点.结果 共监测390人,麻疹接种率为94.10%,麻疹血清抗体阳性率为99.23%.中枢

  16. 心理护理在不同年龄段住院儿童患者护理中的作用%Effect of psychological nursing in the nursing of hospitalized children of different ages

    Institute of Scientific and Technical Information of China (English)

    刘玉婷

    2016-01-01

    Objective To analyze and explore the effect of psychological nursing intervention in the clinical nursing of hospitalized children of different ages. Methods 120 children who were hospitalized in the pediatric ward of our hospital from September 2013 to January 2015 children were selected and they were allocated to four groups according to their ages. There were 30 infants of 6 months to 1 year old, 30 children of 1 to 3 years old, 30 preschool children of 3 to 7 years old and 30 preschool children of 7 to 14 years old. Children of different ages were received corresponding psychological intervention. Psychological states between and after psychological intervention of children in all groups were compared. Results After corresponding psychological intervention, bad psychological states of all children have been effectively reduced. And quiet state of children is also significantly better than that before the psychological intervention. Changes in psychological states of children of 7 to 14 years old and children of to 7 years old had no significant difference while the magnitude of psychological state of children in the two groups was significantly better than that of children of 6 months to 1 year old and 1 to 3 years old. Conclusion Hospitalized children of different ages receiving corresponding psychological nursing intervention can helps to reduce anxiety, tension and resistance behavior of children. It can improve the treatment coordination rate of children, worthy of clinical application and promotion.%目的:分析与探讨不同年龄段住院儿童患者临床护理中对应用心理护理干预的作用。方法选取120例2013年9月~2015年1月在我院儿科病房住院的患儿,根据不同年龄段将这些患儿分为四组,30例6个月~1岁婴幼儿,30例1~3岁幼儿,30例3~7岁学龄前儿童,30例7~14岁学龄期儿童,对各年龄段患儿行相对应的心理护理干预。对比各组患儿行心理护理前后的心

  17. 红原县0~3岁儿童营养状况调查%Investigation on nutritional status of children aged 0-3 years in Hongyuan County

    Institute of Scientific and Technical Information of China (English)

    李艳; 李小玉

    2015-01-01

    Objective To evaluate the nutritional status of children aged from 0 to 3 years old in Hongyuan county. Methods Randomly selected 288 cases according to the proportion. In all villages and towns in Hongyuan County. All the children were accurate measurements of height, weight. WHO child growth standards In the 2006 were designated as the reference standard, and through these standards to judge the child malnutrition and divided degree. Then the proportion of different degree of malnutrition were calculated, and statistical analysis was performed. Results The pro-portion of moderate to severe under weigth, stunting, wasting was respectively 15.3%, 17.36% and 6.25%. The under weigth and stunting accounted for 22.67% and 20.00% in the infants less than 1 year of age, the low weight ratio was significantly higher than that of more than 1 years old children, there was significant difference between two groups (P<0.05). Underweight and stunting had no difference in two groups,there was no significant differences between different gender. Conclusion Hongyuan County 0 to 3 years old children, especially 1 years old children, the prevalence rate of malnutrition was significantly higher than that in other area. Remote minority areas should promote the development of medical and health work, to improve the educational level of parents, strengthen scientific feeding knowledge education.%目的:了解红原县0~3岁儿童营养状况。方法在红原县各乡镇按比例随机抽样288例,准确测量儿童身高、体重,用2006年WHO儿童生长标准为参考标准,判断儿童营养不良状况并分度,然后统计分析各种程度营养不良比例。结果中重度体重低下、生长迟缓、消瘦的比例分别为15.3%、17.36%和6.25%;其中小于1岁婴儿体重低下者占22.67%,生长迟缓占20.00%;小于1岁婴儿体重低下比例明显高于大于1岁组,两组比较有显著差异(P<0.05),生长迟缓及消瘦情况比较无显著

  18. Influence of the science intervention for early childhood development on infants' growth and development%儿童早期发展科学干预对婴幼儿生长发育的影响

    Institute of Scientific and Technical Information of China (English)

    高明英; 段娅莉; 徐兵; 张程华; 孙恩; 胡雯

    2011-01-01

    目的:研究儿童早期发展的科学干预活动对婴幼儿生长发育的影响效果.方法:用随机抽样原则分实验组对照组.两组儿童均自出生后接受儿童保健系统管理中常规生长发育监测和精神发育评估指导;同时,实验组儿童还自胎儿5个月开始,实施该院自行设计、符合婴幼儿早期发展特点和发育规律的科学训练方案至婴儿期.两组儿童均在1岁和3岁时采用盖瑟尔(Gesell)婴幼儿发育量表测试其神经心理发育水平.结果:体格发育指标在1岁和3岁时两组儿童中差异均无统计意义.但发育年龄(DA)及发育商(DQ)在1岁时,实验组均高于对照组,差异均有统计学意义(P<0.05);在3岁时实组发育年龄(DA)和发育商(DQ)均高于对照组,其中言语能区和应人能区2个能区差异具有统计学意义(P<0.05).结论:儿童早期发展的科学干预活动可促进婴幼儿的智能发育,并可产生深远的长期持续影响.%Objective: To explore the effect of the science intervention for early childhood development on growth and development of 0 ~ 3 years old infant. Methods: Comparing with the Gontrol group, the experimental group was trained by their trained parents every day using" The Early Childhood Development Intervention Plan" designed by the hospital from the embryo to 1 year old. Regularly two groups were evaluated physical and mental development indicators. All children were assessed by Gesell scales of development at 1 and 3 year -old. Results: In 1 and 3 year -old children, there were no differences on items of physical development between the two groups. The development age (DA) and development quotient (DQ) of the experiment group were higher than the control group; there was a significant difference between the two groups of all ability in 1 year - old and part ability in 3 year - old ( P < 0. 05 ) . Conclusion: Early childhood development intervention can promote the growth of infant's intelligence, and

  19. Avaliação prognóstica da doença coronária estável através de um novo escore Evaluación pronóstica de la enfermedad coronaria estable a través de un nuevo score New prognostic score for stable coronary disease evaluation

    Directory of Open Access Journals (Sweden)

    Fernanda Coutinho Storti

    2011-05-01

    Full Text Available FUNDAMENTO: A necessidade de melhorar a acurácia do teste de esforço, determinou o desenvolvimento de escores, cuja aplicabilidade já foi amplamente reconhecida. OBJETIVO: Avaliação prognóstica do coronariopata estável através de um novo escore simplificado. MÉTODOS: Um novo escore foi aplicado em 372 coronariopatas multiarteriais e função ventricular preservada, 71,8% homens, idade média 59,5 (± 9,07 anos, randomizados para angioplastia, revascularização cirúrgica e tratamento clínico, acompanhados por 5 anos. Óbito cardiovascular foi o desfecho primário. Infarto do miocárdio não-fatal, óbito e re-intervenção formaram o desfecho combinado secundário. O escore baseou-se numa equação previamente validada resultante da soma de 1 ponto para: sexo masculino, história de infarto, angina, diabete, uso de insulina e ainda 1 ponto para cada década de vida a partir dos 40 anos. Teste positivo adicionou 1 ponto. RESULTADOS: Ocorreram 36 óbitos (10 no grupo angioplastia, 15 no grupo revascularização e 11 no grupo clínico, p = 0,61. Observou-se 93 eventos combinados: 37 no grupo angioplastia, 23 no grupo revascularização e 33 no grupo clínico (p = 0,058. 247 pacientes apresentaram escore clínico > 5 pontos e 216 > 6 pontos. O valor de corte > 5 ou > 6 pontos identificou maior risco, com p = 0,015 e p = 0,012, respectivamente. A curva de sobrevida mostrou uma incidência de óbito após a randomização diferente naqueles com escore > 6 pontos (p = 0,07, e uma incidência de eventos combinados diferente entre pacientes com escore 6 pontos (p = 0,02. CONCLUSÃO: O novo escore demonstrou consistência na avaliação prognóstica do coronariopata estável multiarterial.FUNDAMENTO: La necesidad de mejorar la exactitud de las pruebas de estrés, determinó el desarrollo de los puntajes, cuya aplicación fue ampliamente reconocida. OBJETIVO: La evaluación pronóstica del coronariópata estable a través de un nuevo score

  20. Kre-Celazine(®) as a viable treatment for juvenile rheumatoid arthritis/juvenile idiopathic arthritis - a pilot study.

    Science.gov (United States)

    Golini, Jeff; Jones, Wendy Lou

    2014-09-01

    The purpose of this study was to ascertain whether an oral, non-prescription, nutritional supplement compound composed of a proprietary alkali-buffered creatine monohydrate and cetylated fatty acids mixture (Kre-Celazine(®)) was efficacious in reducing or eliminating refractory pain and inflammation, without untoward effects, in Juvenile Rheumatoid Arthritis (JRA), which is also called Juvenile Idiopathic Arthritis (JIA). JRA/JIA is a patho-physiologically complex, chronic childhood autoimmune inflammatory disease of unknown etiology. Numerous studies have unsuccessfully attempted to pinpoint a possible common initiation event. Officially considered an affliction of children below the age of 16 years, an initial diagnosis has been confirmed in infants less than 1 year old, to individuals older then 17 years. In this study, sixteen juveniles, ages 7 through 16 years, experiencing long-standing, unremitting pain and inflammation despite previous use of prescription anti-inflammatory drugs and NSAIDs, were enrolled in a 30-day, open-label clinical study and treated with Kre-Celazine. Efficacy of this nutritional supplement was determined by the juvenile's personal physician and based on observations of the following: (1) significant reduction or elimination of palpable signs of inflammation; (2) renormalization of range of motion; (3) reduction or absence of perceived pain as reported to the physician by the patient; (4) renormalization of C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) values. In addition, the individual's previous steroid or non-steroidal anti-inflamatory medication(s) were reduced or eliminated in a stepwise progressive fashion during the study.