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Sample records for 1-year-old erythrocebus patas

  1. Locomotor Anatomy and Behavior of Patas Monkeys (Erythrocebus patas with Comparison to Vervet Monkeys (Cercopithecus aethiops

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    Adrienne L. Zihlman

    2013-01-01

    Full Text Available Patas monkeys (Erythrocebus patas living in African savanna woodlands and grassland habitats have a locomotor system that allows them to run fast, presumably to avoid predators. Long fore- and hindlimbs, long foot bones, short toes, and a digitigrade foot posture were proposed as anatomical correlates with speed. In addition to skeletal proportions, soft tissue and whole body proportions are important components of the locomotor system. To further distinguish patas anatomy from other Old World monkeys, a comparative study based on dissection of skin, muscle, and bone from complete individuals of patas and vervet monkeys (Cercopithecus aethiops was undertaken. Analysis reveals that small adjustments in patas skeletal proportions, relative mass of limbs and tail, and specific muscle groups promote efficient sagittal limb motion. The ability to run fast is based on a locomotor system adapted for long distance walking. The patas’ larger home range and longer daily range than those of vervets give them access to highly dispersed, nutritious foods, water, and sleeping trees. Furthermore, patas monkeys have physiological adaptations that enable them to tolerate and dissipate heat. These features all contribute to the distinct adaptation that is the patas monkeys’ basis for survival in grassland and savanna woodland areas.

  2. Thermoregulation in Erythrocebus patas - A thermal balance study

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    Kolka, M. A.; Elizondo, R. S.

    1983-01-01

    The ability of nonacclimated patas monkeys (Erythrocebus patas) to maintain a constant core temperature at six ambient temperatures from 15 to 40 C is investigated experimentally in 3 male and 3 female animals weighing 3.9-6.0 kg. The monkeys were permitted to reach equilibrium at the test Ta for at least 2 h before O2-uptake, CO2 output, weighted skin temperature (Tsk), rectal temperature (Tre), respiratory evaporative water loss (Eresp) and total evaporative water loss (Etot) were measured for 30 min. The results are presented in tables and graphs. Tsk is found to vary (from about 30.7 to about 37.2 C) with Ta, while Tre increases only from 37.6 to 38.4 C; Etot increases from about 9 to about 76 W/sq m, mainly due to eccrine sweating. Total body conductance, Tsk, and Tre are shown to be lower (the conductance significantly) at 40 C than those of rhesus monkeys. It is suggested that the enhanced heat tolerance of E. patas makes this species an appropriate subject for further studies of primate temperature regulation.

  3. Microhabitat preference and vertical use of space by patas monkeys (Erythrocebus patas) in relation to predation risk and habitat structure.

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    Enstam, Karin L; Isbell, Lynne A

    2004-01-01

    Habitat structure can be important in determining habitat preference of animals because it is often closely linked to factors that affect survival and reproduction, such as food availability and predation risk. Here we examine the ways in which microhabitat structure and predation risk affect the habitat preference of wild patas monkeys (Erythrocebus patas). Patas monkeys in Kenya are typically restricted to Acacia drepanolobium habitat, but within our study group's home range, there are two distinct microhabitats, one with taller trees ('tall microhabitat') and one with apparently perennially shorter trees ('short microhabitat'). Examination of ranging behavior indicates that the patas monkeys preferred the tall microhabitat. In the tall microhabitat, focal animals climbed into trees that were significantly taller than average, indicating that they preferred tall trees. Female patas monkeys spent more time scanning from tall trees than from short trees and detected predators only from taller than average trees, based on alarm call data. Their use of tall trees may have decreased their predation risk by increasing their ability to detect predators. We found no evidence of increased food availability or reduced predator presence in the tall microhabitat that could contribute to the monkeys' preference for the tall microhabitat.

  4. Interspecific and temporal variation of ant species within Acacia drepanolobium ant domatia, a staple food of patas monkeys (Erythrocebus patas) in Laikipia, Kenya.

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    Isbell, Lynne A; Young, Truman P

    2007-12-01

    The ants that live in the swollen thorns (domatia) of Acacia drepanolobium are staple foods for patas monkeys (Erythrocebus patas). To obtain a better understanding of these insects as resources for patas monkeys, we sampled the contents of 1,051 swollen thorns (ant domatia) over a 22-month period from December 1999 to September 2001, in Laikipia, Kenya. First, we confirmed that of the four species of ants that live on A. drepanolobium, Crematogaster sjostedti, the competitively dominant ant in this system, does not rear significant brood in the swollen thorns and is therefore not a major food item of patas monkeys. Second, across the other three species that do use swollen thorns for rearing their brood, C. nigriceps, C. mimosae, and Tetraponera penzigi, the number of worker ants per swollen thorn increased with increasing competitive dominance. Third, although there was considerable month-to-month variation in the number of workers, immatures, and especially alates (winged reproductives) within species, there was less variation across species because ant production was asynchronous. Variation in domatia contents was poorly related to rainfall for each of the three species. Finally, distal thorns held more alates and fewer workers than interior thorns, and branches higher off the ground held more alates and more workers than lower branches. For the numerically dominant C. mimosae, higher branches held significantly more immature ants than did lower branches. Ants are reliable food resources for patas monkeys, and are probably more reliable than many plant resources in this highly seasonal environment. We estimate that patas monkeys may get as much as a third of their daily caloric needs from these ants year-round. As ants and other insects are widely consumed by primates, we suggest that greater consideration be given to species differences in animal food choices and that further studies be conducted to examine the degree to which ants influence energy intake and

  5. Influence of environment enrichment to the behaviors of Erythrocebus patas in captive%环境丰容对赤猴行为分配影响的研究

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    陈霖; 叶安城; 池章伟

    2014-01-01

    In 2011, the 3 male and 3 female Erythrocebus patas raised in Fuzhou Zoo suffered from such unhealthy growing conditions as unitary behavior, coarse hairs, dry and ruptured tails and claudication, etc. They were transferred to a cage with certain environment enrichment and stayed for one year. Compared with the conditions in the previous cage, the allocations of Erythrocebus patas' day-time behaviors of foraging and sports increase by 61.3% and 213.2% respectively, and their walking and resting time decrease by 41.2% and 26.7% respectively. Now, the Erythrocebus patas have fine hairs, their tails recover to normal conditions, and claudication basically disappears.%2011年初福州动物园饲养的3公3雌赤猴出现行为单一、毛发粗糙、尾部干枯断裂、见有跛行等不良生长状况。为了改变猴群出现的不良状况,福州动物园将赤猴转移至新兽舍饲养,该新兽舍有较大的活动空间、良好的植被覆盖,还在新兽舍中安置有假山、攀网、跑道等设施供赤猴锻炼。此外,还将赤猴部分饲料由定点投喂改为抛洒投喂。经过约一年适应,赤猴昼间行为分配相较旧笼时觅食和运动行为分别提高61.3%、213.2%;行走和休息时间分别减少41.2%、26.7%,猴群被毛良好,尾部恢复正常,跛行现象基本消失。

  6. Social Development: 1 Year Olds

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    ... Stages Listen Español Text Size Email Print Share Social Development: 1 Year Olds Page Content Article Body ... will develop a very specific image of his social world, friends, and acquaintances. He is at its ...

  7. Language Development: 1 Year Olds

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    ... Stages Listen Español Text Size Email Print Share Language Development: 1 Year Olds Page Content Article Body ... assured, it’s not your imagination. He’s developing his language and comprehension skills right on schedule. This giant ...

  8. Mitochondrial compromise in 3-year old patas monkeys exposed in utero to human-equivalent antiretroviral therapies.

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    Liu, Yongmin; Shim Park, Eunwoo; Gibbons, Alexander T; Shide, Eric D; Divi, Rao L; Woodward, Ruth A; Poirier, Miriam C

    2016-08-01

    Antiretroviral (ARV) drug therapy, given during pregnancy for prevention of mother-to-child transmission of human immunodeficiency virus 1 (HIV-1), induces fetal mitochondrial dysfunction in some children. However, the persistence/reversibility of that dysfunction is unclear. Here we have followed Erythrocebus patas (patas) monkey offspring for up to 3 years of age (similar in development to a 15-year old human) after exposure of the dams to human-equivalent in utero ARV exposure protocols. Pregnant patas dams (3-5/exposure group) were given ARV drug combinations that included zidovudine (AZT)/lamivudine (3TC)/abacavir (ABC), or AZT/3TC/nevirapine (NVP), for the last 10 weeks (50%) of gestation. Infants kept for 1 and 3 years also received drug for the first 6 weeks of life. In offpsring at birth, 1 and 3 years of age mitochondrial morphology, examined by electron microscopy (EM), was compromised compared to the unexposed controls. Mitochondrial DNA (mtDNA), measured by hybrid capture chemiluminescence assay (HCCA) was depleted in hearts of patas exposed to AZT/3TC/NVP at all ages (P year-old patas offspring was ∼50% reduced in AZT/3TC/ABC-exposed patas (P year-old patas sustain persistent mitochondrial dysfunction as a result of perinatal ARV drug exposure. Environ. Mol. Mutagen. 57:526-534, 2016. © 2016 Wiley Periodicals, Inc.

  9. Nutritional benefits of Crematogaster mimosae ants and Acacia drepanolobium gum for patas monkeys and vervets in Laikipia, Kenya.

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    Isbell, Lynne A; Rothman, Jessica M; Young, Peter J; Rudolph, Kathleen

    2013-02-01

    Patas monkeys (Erythrocebus patas) are midsized primates that feed extensively on the gum of Acacia drepanolobium and the ants are housed in swollen thorns of this Acacia. Their diet resembles that expected more of smaller bodied primates. Patas monkeys are also more like smaller bodied primates in reproducing at high rates. We sought to better understand the convergence of patas monkeys with smaller bodied primates by comparing their feeding behavior on ants and gum with that of closely related, sympatric vervets (Chlorocebus pygerythrus), and analyzing the nutrient content of the gum of A. drepanolobium and of Crematogaster mimosae, the most common ant species eaten by patas monkeys in Laikipia, Kenya. All occurrences of feeding and moving during focal animal sampling revealed that 1) patas monkeys seek A. drepanolobium gum but vervets avoid it; 2) both species open swollen thorns most often in the morning when antsare less active; 3) patas monkeys continually feed onswollen thorns and gum while moving quickly throughout the day, whereas vervets reduce their consumption of these items and their travel rate at mid-day, and; 4) vervets eat young swollen thorns at a higher rate than patas monkeys. Patas monkeys are able to spend little time acquiring substantial amounts of energy, protein, and minerals from A. drepanolobium gum and C. mimosae ants each day. These findings, when coupled with evidence of causes of infant and adult female mortality, suggest that reproductive success of female patas monkeys is more immediately affected by illness, disease, interactions between adults and infants, and access to water than by food.

  10. Management of tongue and lip laceration due to dystonia in a 1-year-old infant

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    J P Beena

    2017-01-01

    Full Text Available This case report describes the management of tongue and lip lacerations due to dystonia in a 1-year-old infant. A splint was given to raise the bite and prevent repeated trauma and aid in healing of the oral tissue. This paper highlights the importance of pediatric dentist's role in improving quality of patient care in an intensive care unit.

  11. Dentin caries risk indicators in 1-year-olds. A two year follow-up study.

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    Hultquist, Ann Ingemansson; Bågesund, Mats

    2016-11-01

    Early childhood caries (ECC) risk factors are suspected to vary between regions with different caries prevalence. Identify ECC risk factors for 1-year-olds predicting dentin caries at 3 years of age in a region with low caries prevalence. Caries risk was assessed by dental hygienist or dental assistant in 779 one-year-olds. The oral mutans streptococci (MS) score was performed from a tooth surface or (in pre-dentate children) from oral mucosa. A parental questionnaire with questions regarding family factors (siblings with or without caries), general health, food habits (night meals, breastfeeding, other beverage than water), oral hygiene habits and emerged teeth were answered by parents of the 1-year-olds. Dentin caries was assessed when the children were 3-year-olds. Simple and multiple logistic regression analyses were used for identification of caries-associated factors. An increased caries risk was assessed in 4.4% of the 1-year-olds. Dentin caries was found in 2.6% of the 3-year-olds. Caries risk at 1 year was associated with caries at 3 years (OR = 6.5, p = .002). Multiple regression analysis found the variables Beverages other than water (OR = 7.1, p year-olds in a region with low caries experience.

  12. Evidence of Bordetella pertussis infection in vaccinated 1-year-old Danish children

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    von Linstow, Marie-Louise; Pontoppidan, Peter Lotko; von König, Carl-Heinz Wirsing

    2010-01-01

    We measured IgA and IgG antibodies to pertussis toxin (PT) and filamentous hemagglutinin (FHA) in sera from 203 1-year-old children who had received one to three doses of a monocomponent PT toxoid vaccine. Ten children (5%) had IgA antibody to PT indicating recent infection; seven of these children...... had received three doses of vaccine. PT IgA responders did not have significantly longer coughing episodes than PT IgA non-responders. Since an IgA antibody response occurs in only approximately 50% of infected children, the actual infection rate in our cohort is estimated to approximately 10......%. The apparent high Bordetella pertussis infection rate in Danish infants suggests that the monocomponent PT toxoid vaccine used in Denmark has limited efficacy against B. pertussis infection. A prospective immunization study comparing a multi-component vaccine with the present monocomponent PT toxoid vaccine...

  13. Supratentorial arachnoid cyst management by cystoperitoneal shunt in a 1-year-old European cat

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    Mathieu Taroni

    2015-07-01

    Full Text Available Arachnoid cysts are defined as an accumulation of fluid within the arachnoid membrane. Feline intracranial arachnoid cysts are seldom reported, with only three cases in the veterinary literature. A 1-year-old male neutered European cat with a 24 h history of seizures was presented to the small animal neurology department at Vetagro Sup, Lyon. Magnetic resonance imaging (MRI revealed a large intracranial arachnoid cyst ventral to the brain in the left temporal area. Cystoperitoneal shunt placement resulted in complete resolution of the cyst without recurrence (follow-up MRIs 3 weeks and 21 months after surgery. Anticonvulsant treatment (phenobarbital 2.5 mg/kg q12h was initiated at presentation and gradually stopped after 17 months. Seizures recurred 4 months after ending treatment, and seizure therapy was therefore restarted at the initial dose. We report a case of an intracranial arachnoid cyst in an unusual location not previously described. A cystoperitoneal shunt resolved the cyst without complications. Maintenance anticonvulsant treatment was required to control symptomatic epilepsy.

  14. A 1-year-old boy with persistent, generalized eruption. Urticaria pigmentosa.

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    Mir, Adnan; Chamlin, Sarah L

    2014-01-01

    A healthy 1-year-old boy born at full term after an uncomplicated pregnancy presented to the dermatology clinic for a widespread eruption with gradual onset since 3 months of age. He was otherwise well, afebrile, feeding well, and gaining weight appropriately. The child was overall asymptomatic, though some of his lesions occasionally became red and pruritic. His mother noticed that after mild illnesses, he was more prone to these flares. She denied flushing, vomiting, diarrhea, respiratory distress, and irritability. He was meeting all developmental milestones and started walking at 11 months of age. The remainder of his review of systems was unremarkable, and family history was noncontributory. Physical exam revealed a well-appearing, well-nourished, playful, and interactive toddler. There were innumerable discrete and coalescing pink-brown macules and papules concentrated on the trunk and extending onto the proximal upper and lower extremities bilaterally, as well as the neck and lower face. Stroking the lesions quickly led to development of erythematous edematous wheals. There was no hepatosplenomegaly, and the lymph node exam was unremarkable.

  15. Development of 1-year-old computational phantom and calculation of organ doses during CT scans using Monte Carlo simulation.

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    Pan, Yuxi; Qiu, Rui; Gao, Linfeng; Ge, Chaoyong; Zheng, Junzheng; Xie, Wenzhang; Li, Junli

    2014-09-21

    With the rapidly growing number of CT examinations, the consequential radiation risk has aroused more and more attention. The average dose in each organ during CT scans can only be obtained by using Monte Carlo simulation with computational phantoms. Since children tend to have higher radiation sensitivity than adults, the radiation dose of pediatric CT examinations requires special attention and needs to be assessed accurately. So far, studies on organ doses from CT exposures for pediatric patients are still limited. In this work, a 1-year-old computational phantom was constructed. The body contour was obtained from the CT images of a 1-year-old physical phantom and the internal organs were deformed from an existing Chinese reference adult phantom. To ensure the organ locations in the 1-year-old computational phantom were consistent with those of the physical phantom, the organ locations in 1-year-old computational phantom were manually adjusted one by one, and the organ masses were adjusted to the corresponding Chinese reference values. Moreover, a CT scanner model was developed using the Monte Carlo technique and the 1-year-old computational phantom was applied to estimate organ doses derived from simulated CT exposures. As a result, a database including doses to 36 organs and tissues from 47 single axial scans was built. It has been verified by calculation that doses of axial scans are close to those of helical scans; therefore, this database could be applied to helical scans as well. Organ doses were calculated using the database and compared with those obtained from the measurements made in the physical phantom for helical scans. The differences between simulation and measurement were less than 25% for all organs. The result shows that the 1-year-old phantom developed in this work can be used to calculate organ doses in CT exposures, and the dose database provides a method for the estimation of 1-year-old patient doses in a variety of CT examinations.

  16. Two isoforms of cyclooxygenase contribute to augmented endothelium-dependent contractions in femoral arteries of 1-year-old rats

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    Yi SHI; Ricky YK MAN; Paul M VANHOUTTE

    2008-01-01

    Aim: The present experiments were designed to study the changes in endothe-lium-dependent contractions with aging. Methods: The rat femoral arteries of 20-week and 1-year-old rats with and without endothelium were suspended in organ chambers to record isometric tension. The production of oxygen-derived free radicals in the endothelium was measured with 2',7'-dichiorodihydrofluorescein diacetate (DCF) using confocal microscopy. Protein presences were determined by Western blotting. Results: In the arteries from the 1-year-old rats, endothe-lium-dependent relaxations to A23187 were reduced, but the endothelium-depen-dent contractions to A23187 (in the presence of Nω-nitro-L-arginine methyl ester hydrochloride [L-NAME; an inhibitor of nitric oxide synthase]) were augmented, demonstrating endothelial dysfunction with aging. Indomethacin normalized the responses, suggesting that a cyclooxygenase (COX)-dependent contraction is prominent in aging. The endothelium-dependent contractions were also prevented by terntroban (a blocker of thromboxane-prostanoid receptors), confirming the activation of thromboxane-prostanoid receptors on vascular smooth muscle. Valeryl salicylate and NS-398 (preferential inhibitors of COX-1 and COX-2, respectively) partially reduced the response, indicating that both COX-1 and COX-2 are involved. Western blotting confirmed the upregulation of both isoforms in the arteries of the 1-year-old rats. In the presence of L-NAME, A23187 increased the DCF fluores-cence in the endothelium, demonstrating that the production of oxygen-derived free radicals contributes to endothelium-dependent contractions. The activity of catalase was reduced in the arteries with endothelium of 1-year-old rats, indicating that hydrogen peroxide is the likely mediator of increased oxidative stress in the aging endothelium. Conclusion: Endothelium-dependent contractions are aug-mented with aging. Oxidative stress potentiates the response, and both COX-1 and COX-2 are

  17. Nocturnal heart rate variability in 1-year-old infants analyzed by using the Least Square Cosine Spectrum Method.

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    Kochiya, Yuko; Hirabayashi, Akari; Ichimaru, Yuhei

    2017-09-16

    To evaluate the dynamic nature of nocturnal heart rate variability, RR intervals recorded with a wearable heart rate sensor were analyzed using the Least Square Cosine Spectrum Method. Six 1-year-old infants participated in the study. A wearable heart rate sensor was placed on their chest to measure RR intervals and 3-axis acceleration. Heartbeat time series were analyzed for every 30 s using the Least Square Cosine Spectrum Method, and an original parameter to quantify the regularity of respiratory-related heart rate rhythm was extracted and referred to as "RA (RA-COSPEC: Respiratory Area obtained by COSPEC)." The RA value is higher when a cosine curve is fitted to the original data series. The time sequential changes of RA showed cyclic changes with significant rhythm during the night. The mean cycle length of RA was 70 ± 15 min, which is shorter than young adult's cycle in our previous study. At the threshold level of RA greater than 3, the HR was significantly decreased compared with the RA value less than 3. The regularity of heart rate rhythm showed dynamic changes during the night in 1-year-old infants. Significant decrease of HR at the time of higher RA suggests the increase of parasympathetic activity. We suspect that the higher RA reflects the regular respiratory pattern during the night. This analysis system may be useful for quantitative assessment of regularity and dynamic changes of nocturnal heart rate variability in infants.

  18. Transhepatic implant of a trimmed Melody™ valved stent in tricuspid position in a 1-year-old infant.

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    Cools, Bjorn; Rega, Filip; Gewillig, Marc

    2017-02-15

    Percutaneous valved stent implantation is precluded in small infants because large delivery sheaths and large devices. We describe a procedure in a 1-year-old boy in whom a 19 mm Epic™ valve in tricuspid position had become dysfunctional. As the internal diameter of the prosthetic valve was about 16 mm, the only available valve was the Melody™ valved stent. Technical modifications were required to address issues like venous access, the bulky delivery system, and the length of the valved stent. The Melody™ valved stent was surgically trimmed and mounted on a 16 mm Tyshak balloon, access was provided transhepatically through a short 18 Fr sheath. After deployment, the intrahepatic route was sealed with two vascular plugs (8 and 10 mm) in tandem. The procedure was uncomplicated with perfect valve function 18 months after implant. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  19. NCBI nr-aa BLAST: CBRC-DRER-26-0212 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-DRER-26-0212 gb|AAD47790.1| C-C chemokine receptor 5 [Erythrocebus patas] gb|A...AD47791.1| C-C chemokine receptor 5 [Erythrocebus patas] gb|AAD47803.1| C-C chemokine receptor 5 [Erythrocebus... patas] gb|AAD47805.1| C-C chemokine receptor 5 [Erythrocebus patas] gb|AAD47807.1| C-C chemokine receptor 5 [Erythrocebus... patas] gb|AAD47808.1| C-C chemokine receptor 5 [Erythrocebus patas] AAD47790.1 2e-10 27% ...

  20. Effect observation of 1-year-old child health%1岁儿童保健效果观察

    Institute of Scientific and Technical Information of China (English)

    李汉广

    2015-01-01

    Objective To explore effect of 1-year-old child health, and to improve participation rate of child health.Methods A total of 200 children at 1 year old in child health were divided into observation group (regular child health, 108 cases) and control group (irregular child health, 92 cases) by their participation frequency. Comparisons were made on nutritional status and physical development status between the two groups. Denver developmental screening test (DDST) was applied to evaluate their intelligent development situation. Results There was no statistically significant difference of stature and weight between the two groups (P>0.05). The observation group had higher hemoglobin level, lower bone alkaline phosphatase level and lower incidences of iron-deficiency anemia and rickets than the control group. The difference had statistical significance (P0.05);观察组血红蛋白水平高于对照组,骨碱性磷酸酶水平、缺铁性贫血及佝偻病发生率均低于对照组,差异有统计学意义(P<0.05);观察组儿童各项智能发育评分均高于对照组,差异有统计学意义(P<0.05)。结论积极参加儿童保健可促进儿童生长发育,应加强家长的儿童保健意识,以改善儿童保健状况。

  1. [Clinical characteristics and management of infants less than 1-year-old suspected with allergy to cow's milk protein].

    Science.gov (United States)

    Errázuriz, Germán; Lucero, Yalda; Ceresa, Sergio; Gonzalez, Mónica; Rossel, Maureen; Vives, Andrés

    Cow's milk protein allergy (CMPA) is highly prevalent in infants (2-5%). It has a wide clinical spectrum, and confirmation through an oral food challenge (OFC) is relevant for its differential diagnosis. Information on this topic is scarce in Chile. To describe the demographic and clinical features of infants with suspected CMPA. A retrospective study of patients<1 year-old, treated for suspected CMPA between 2009 and 2011. Demographic data, symptoms of atopy, nutrition at the time of diagnosis, CMPA symptoms, diagnostic studies, and response to treatment were recorded. Diet response at least 4 weeks after milk modification, and clinical behavior when suspected foods were added back to the diet were considered standard diagnostic criteria. Descriptive statistics were performed using Epiinfo ™ software. The study included 106 infants, of whom, 51% male, 80% term newborns, 74% with≥1 atopic parent, and 34% with ≥1 parent/sibling with food allergy. The median age at onset of symptoms was 1.5 months (range 1.5-2m). Almost half (46%) were breast-feeding≥6m, with 15% receiving formula milk since the neonatal period, and 49% before the third month. Common symptoms were: vomiting (63%), colic (49%), and bleeding on passing stools (41%). No anaphylaxis was identified, and 61% had≥2 symptoms at debut. Only 34% were subjected to OFC. The most frequently requested tests were, test patch (43%), prick test (40%), and blood in stools (37%). 43% breast feeding with exclusion diet, 24% extensively hydrolysed formula, 26% amino acid formula, and 7% others. Demographic characteristics and risk factors were similar to those previously described in international literature. Clinical presentation was early in life, and digestive symptoms predominated. OFC was underused for diagnosis, and most of the tests requested did not change management. Copyright © 2016 Sociedad Chilena de Pediatría. Publicado por Elsevier España, S.L.U. All rights reserved.

  2. Diet in 1-year-old farm and control children and allergy development: results from the FARMFLORA birth cohort

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    Karin Jonsson

    2016-08-01

    Full Text Available Background: A farming environment confers strong protection against allergy development. We have previously shown that farming mothers consume more full-fat dairy than control mothers, who instead consume more low-fat dairy, margarine, and oils; margarine and oil intake was associated with increased risk of allergy development in their children. Objectives: The aims of this study were to investigate the differences in diet between children in farming and control families at 1 year of age, to investigate the relation between the diets of the mothers and their children, and to relate the children's diet to allergy development. Design: The diet of 1-year-old children from dairy farming families (n=28 and from control families in the same rural area (n=37 was assessed by 24-h dietary recalls, followed by 24-h food diaries. Allergy was diagnosed by pediatricians at 3 years of age using strict predefined criteria. Results: Farm children had a higher intake of farm milk, whole cream, cholesterol, saturated fat, and fat in total and tended to eat more butter, while controls consumed more carbohydrates and poultry and tended to eat more margarine. Farm children also had higher intakes of homemade porridge/gruel, oily fish, and iodine. The intake of butter and whole milk in children and mothers correlated significantly in farm families but not in controls. A weak negative association was found between seafood intake and allergy development, while allergy was positively associated with the intake of pork as well as zinc in the control group; these intakes also correlated with each other. Conclusions: Consistent with mothers in farming families, the children consumed more full-fat dairy and saturated fat than did controls, but this could not be linked to the low risk of allergy in the farming group. Seafood intake might protect against allergy development, in accordance with earlier findings.

  3. Diet in 1-year-old farm and control children and allergy development: results from the FARMFLORA birth cohort

    Science.gov (United States)

    Jonsson, Karin; Green, My; Barman, Malin; Sjöberg, Agneta; Brekke, Hilde K.; Wold, Agnes E.; Sandberg, Ann-Sofie

    2016-01-01

    Background A farming environment confers strong protection against allergy development. We have previously shown that farming mothers consume more full-fat dairy than control mothers, who instead consume more low-fat dairy, margarine, and oils; margarine and oil intake was associated with increased risk of allergy development in their children. Objectives The aims of this study were to investigate the differences in diet between children in farming and control families at 1 year of age, to investigate the relation between the diets of the mothers and their children, and to relate the children's diet to allergy development. Design The diet of 1-year-old children from dairy farming families (n=28) and from control families in the same rural area (n=37) was assessed by 24-h dietary recalls, followed by 24-h food diaries. Allergy was diagnosed by pediatricians at 3 years of age using strict predefined criteria. Results Farm children had a higher intake of farm milk, whole cream, cholesterol, saturated fat, and fat in total and tended to eat more butter, while controls consumed more carbohydrates and poultry and tended to eat more margarine. Farm children also had higher intakes of homemade porridge/gruel, oily fish, and iodine. The intake of butter and whole milk in children and mothers correlated significantly in farm families but not in controls. A weak negative association was found between seafood intake and allergy development, while allergy was positively associated with the intake of pork as well as zinc in the control group; these intakes also correlated with each other. Conclusions Consistent with mothers in farming families, the children consumed more full-fat dairy and saturated fat than did controls, but this could not be linked to the low risk of allergy in the farming group. Seafood intake might protect against allergy development, in accordance with earlier findings. PMID:27534847

  4. Bacillus anthracis acetyltransferases PatA1 and PatA2 modify the secondary cell wall polysaccharide and affect the assembly of S-layer proteins.

    Science.gov (United States)

    Lunderberg, J Mark; Nguyen-Mau, Sao-Mai; Richter, G Stefan; Wang, Ya-Ting; Dworkin, Jonathan; Missiakas, Dominique M; Schneewind, Olaf

    2013-03-01

    The envelope of Bacillus anthracis encompasses a proteinaceous S-layer with two S-layer proteins (Sap and EA1). Protein assembly in the envelope of B. anthracis requires S-layer homology domains (SLH) within S-layer proteins and S-layer-associated proteins (BSLs), which associate with the secondary cell wall polysaccharide (SCWP), an acetylated carbohydrate that is tethered to peptidoglycan. Here, we investigated the contributions of two putative acetyltransferases, PatA1 and PatA2, on SCWP acetylation and S-layer assembly. We show that mutations in patA1 and patA2 affect the chain lengths of B. anthracis vegetative forms and perturb the deposition of the BslO murein hydrolase at cell division septa. The patA1 and patA2 mutants are defective for the assembly of EA1 in the envelope but retain the ability of S-layer formation with Sap. SCWP isolated from the patA1 patA2 mutant lacked acetyl moieties identified in wild-type polysaccharide and failed to associate with the SLH domains of EA1. A model is discussed whereby patA1- and patA2-mediated acetylation of SCWP enables the deposition of EA1 as well as BslO near the septal region of the B. anthracis envelope.

  5. Tres modelos de patas de arquetas nazar??es

    OpenAIRE

    Fern??ndez Puertas, Antonio

    2001-01-01

    Se estudian tres modelos de patas de bronce de cajas nazar??es, datables entre 1345 a 1354 por la hallada en la Puerta de las Albercas de la Alhambra, construida por Yusuf I. Adem??s del ejemplar del Museo de la Alhambra, hay otros dos tipos en el Instituto de Valencia de Don Juan de Madrid, uno en las cuatro patas de una caja de taracea y otro en un ejemplar ??nico, sin duda el m??s bello y mejor ejecutado de los tres modelos.

  6. A congenital anterior urethral diverticulum associated with obstructive urinary symptoms in a 1-year-old male child: A case report and review of the literature

    Directory of Open Access Journals (Sweden)

    Mehmet Hanifi Okur

    2015-05-01

    Full Text Available Congenital anterior urethral diverticula are rarely found in children. We present the case of a 1-year-old male child with a congenital anterior urethral diverticulum. This condition can lead to obstructive lower urinary tract symptoms and urosepsis. The clinical presentation, diagnosis, and management of this rare condition are discussed in this report. The diagnosis was made using retrograde urethrography. Patient was treated with open diverticulectomy and urethroplasty

  7. Obesogenic dietary intake in families with 1-year-old infants at high and low obesity risk based on parental weight status: baseline data from a longitudinal intervention (Early STOPP)

    OpenAIRE

    Svensson, Viktoria; Sobko, Tanja; Ek, Anna; Forssén, Michaela; Ekbom, Kerstin; Johansson, Elin; Nowicka, Paulina; Westerståhl, Maria; Riserus, Ulf; Marcus, Claude

    2015-01-01

    Purpose To compare dietary intake in 1-year-old infants and their parents between families with high and low obesity risk, and to explore associations between infant dietary intake and relative weight. Methods Baseline analyses of 1-year-old infants (n = 193) and their parents participating in a longitudinal obesity intervention (Early STOPP) were carried out. Dietary intake and diet quality indicators were compared between high- and low-risk families, where obesity risk was based on parental...

  8. Predictors and dietary consequences of frequent intake of high-sugar, low-nutrient foods in 1-year-old children participating in the ABIS study.

    Science.gov (United States)

    Brekke, Hilde K; van Odijk, Jenny; Ludvigsson, Johnny

    2007-01-01

    Foods rich in sugar have been suggested to contribute to the increasing prevalence of obesity in children. The aim of this report is to investigate the dietary pattern in 1-year-old children who frequently receive foods rich in sugar but low in nutrients and to study associated demographic and parental factors. During 1977-9, 21,700 infants were invited to participate in this prospective, population-based, longitudinal cohort study. Screening questionnaires were completed for 16,070 infants after delivery. Follow-up questionnaires from 10,762 children at 1 year of age are included in the analysis. It was found that 24% of the children received sweets/pastries more often than one or two times per week. They had a higher intake of French fries, potato crisps and cream as well as a lower intake of fruit and vegetables. A frequent intake of sugar-rich, low-nutrient foods was significantly associated with several maternal factors (high intake of sweets/pastries during pregnancy, young age, mother living alone) as well as presence of older siblings. Maternal smoking during pregnancy and maternal overweight were of borderline significance. Parental education level was inversely associated with the frequency of intake of sweets/pastries in the child. Children who frequently receive sweets/pastries also have an otherwise unfavourable dietary pattern. Several parental and demographic factors were associated with this feeding pattern, especially high intake of sweets/pastries during pregnancy. Screening of pregnant women for risk predictors like consumption of sweets/pastries, young age and smoking could be possible ways of identifying children at future risk for low dietary quality.

  9. Maternal protein restriction during pregnancy and lactation alters central leptin signalling, increases food intake, and decreases bone mass in 1 year old rat offspring.

    Science.gov (United States)

    Qasem, Rani J; Li, Jing; Tang, Hee Man; Pontiggia, Laura; D'mello, Anil P

    2016-04-01

    The effects of perinatal nutrition on offspring physiology have mostly been examined in young adult animals. Aging constitutes a risk factor for the progressive loss of metabolic flexibility and development of disease. Few studies have examined whether the phenotype programmed by perinatal nutrition persists in aging offspring. Persistence of detrimental phenotypes and their accumulative metabolic effects are important for disease causality. This study determined the effects of maternal protein restriction during pregnancy and lactation on food consumption, central leptin sensitivity, bone health, and susceptibility to high fat diet-induced adiposity in 1-year-old male offspring. Sprague-Dawley rats received either a control or a protein restricted diet throughout pregnancy and lactation and pups were weaned onto laboratory chow. One-year-old low protein (LP) offspring exhibited hyperphagia. The inability of an intraperitoneal (i.p.) leptin injection to reduce food intake indicated that the hyperphagia was mediated by decreased central leptin sensitivity. Hyperphagia was accompanied by lower body weight suggesting increased energy expenditure in LP offspring. Bone density and bone mineral content that are negatively regulated by leptin acting via the sympathetic nervous system (SNS), were decreased in LP offspring. LP offspring did not exhibit increased susceptibility to high fat diet induced metabolic effects or adiposity. The results presented here indicate that the programming effects of perinatal protein restriction are mediated by specific decreases in central leptin signalling to pathways involved in the regulation of food intake along with possible enhancement of different CNS leptin signalling pathways acting via the SNS to regulate bone mass and energy expenditure.

  10. SYSTEMATIC FIELD SURVEY ON LIMES TRANSALUTANUS. SĂPATA CASE

    Directory of Open Access Journals (Sweden)

    Eugen S. Teodor

    2017-07-01

    Full Text Available Two adjoined forts and their surroundings, elements of the 3rd century Roman frontier in Dacia – Limes Transalutanus, which were last archaeologically investigated in 1930, were recently systematic surface surveyed, resulting in the identification of the associated civilian settlement in what seemed, at first glance, as an unexpected location, more distant than other military vici the team had previously identified along the same frontier line.Not only the limits of the settlement at Săpata were established, but also the density of occupation and territory division into various functional areas, allowing further interpretations regarding the network of ancient local roads and a better understanding of the way in which the Romans adjusted their built facilities to available resources (water or exploited the strategical features of the relief.Using an efficient, quick and rather inexpensive combination of survey methods (field walking and measurements of the magnetic susceptibility of the soil applied on a 4.8 ha surface, followed by pottery typological and spatial distribution analysis, the investigation team tried to mitigate the challenging vegetation situation, adjusting likewise to the limited resources of a scheduled research project.  Data relevance was increased by applying statistical corrections and using complementary investigation methods in order to cover the various available types of land (relief, vegetation, visibility; while data integration was ensured employing a unitary spatial gridded system for fieldwork and also by relating the obtained results to the high resolution digital terrain model of the sites obtained during UAV photogrammetric aerial survey.In particular, the study takes the opportunity opened by the analysis of the Roman Age pottery found in Săpata vicus to debate on the significance of the traditional, yet not unitary perceived, scholarly division between ‘Chilia-Militari’ ware (dwelling on Dacian

  11. Infinite divisibility and a non-commutative Boolean-to-free Bercovici-Pata bijection

    CERN Document Server

    Belinschi, Serban T; Vinnikov, Victor

    2010-01-01

    We use the theory of fully matricial, or non-commutative, functions to investigate infinite divisibility and limit theorems in operator-valued non-commutative probability. Our main result is an operator-valued analogue of the Bercovici-Pata bijection. An important tool is Voiculescu's subordination property for operator-valued free convolution.

  12. Obesogenic dietary intake in families with 1-year-old infants at high and low obesity risk based on parental weight status: baseline data from a longitudinal intervention (Early STOPP).

    Science.gov (United States)

    Svensson, Viktoria; Sobko, Tanja; Ek, Anna; Forssén, Michaela; Ekbom, Kerstin; Johansson, Elin; Nowicka, Paulina; Westerståhl, Maria; Riserus, Ulf; Marcus, Claude

    2016-03-01

    To compare dietary intake in 1-year-old infants and their parents between families with high and low obesity risk, and to explore associations between infant dietary intake and relative weight. Baseline analyses of 1-year-old infants (n = 193) and their parents participating in a longitudinal obesity intervention (Early STOPP) were carried out. Dietary intake and diet quality indicators were compared between high- and low-risk families, where obesity risk was based on parental weight status. The odds for high diet quality in relation to parental diet quality were determined. Associations between measured infant relative weight and dietary intake were examined adjusting for obesity risk, socio-demographics, and infant feeding. Infant dietary intake did not differ between high- and low-risk families. The parents in high-risk families consumed soft drinks, French fries, and low-fat spread more frequently, and fish and fruits less frequently (p intake of vegetables and fish increased the odds for children being consumers of vegetables (OR 1.7; 95 % CI 1.0-2.9) and fish, respectively (OR 2.5; 95 % CI 1.4-4.4). Infant relative weight was weakly associated with a high intake of milk cereal drink (r = 0.15; p intake, obesity risk, or early feeding patterns. At the age of one, dietary intake in infants is not associated with family obesity risk, nor with parental obesogenic food intake. Milk cereal drink consumption but no other infant dietary marker reflects relative weight at this young age.

  13. 梅州市582例0~1岁儿童喂养状况调查%Investigation on feeding status of 582 0-1-year-old children in Meizhou city

    Institute of Scientific and Technical Information of China (English)

    曾德平

    2012-01-01

    Objective: To understand the feeding status of partial 0 -1 - year - old children in Meizhou city, analyze the existing problems, explore countermeasuies. Methods: Random sampling method was used to investigate the feeding status of 582 0 -1 - year - old hospitalized children from pediatric department of the hospital from March 2004 to December 2009 retrospectively. Results: The pure breast feeding rate of the neonates less than one month was 78.4% , and the breast feeding rate of the infants less than four months was 70. 8%. Conclusion: Targeting to the current situations of relatively low breast feeding rate, adding complementary foods too early, and ablactation too early, correct guidance and intervention should be carried out%目的:了解梅州市部分0~1岁儿童喂养状况,分析存在的问题,探讨应对措施.方法:采用随机抽样法回顾性调查2004年3月~2009年12月在梅州市妇幼保健院儿科住院的582例1~5岁儿童0~1岁时的喂养情况.结果:1个月以内新生儿纯母乳喂养率为78.4%,4个月以内婴儿母乳喂养率为70.8%.结论:应针对目前母乳喂养率偏低、过早添加辅食、过早断乳等现状进行正确引导或干预.

  14. Suitable stocking density and feeding rate of 1 year old Chinese giant salamander, Andrias davidiaus%1龄大鲵适宜养殖密度和投饵率的研究

    Institute of Scientific and Technical Information of China (English)

    刘小召; 杨振江; 涂铁链; 杨开学; 吴凡; 胡乔木; 田海峰; 孟彦; 肖汉兵

    2014-01-01

    在养殖条件下,通过70 d的生长实验研究了养殖密度和投饵率对1龄大鲵( Andrias davidiaus)摄食与生长的影响。养殖密度实验设40、70、100、130、160尾/m2五个组,投饵率实验设1.00%、1.50%、2.00%、2.50%、3.00%五个组,实验结束以增重率( WGR)、特定生长率( SGR)、肥满度( CF)、饵料系数( FCR)为依据,综合评价养殖密度和投饵率对大鲵生长的影响。结果显示:1龄大鲵适宜养殖密度为70尾/m2,该组特定生长率显著高于160尾/m2组;1龄大鲵适宜投饵率为2.00%,该组增重率和特定生长率显著高于3.00%组。%The effects of stocking density and feeding rate on the growth and ingestion of 1 year old giant salamander on the conditions of industrial aquaculture were studied.A 70 -days experiment was conducted in this study.Five daily feeding rates were designed at 1.00%, 1.50%, 2.00%, 2.50%, 3.00% of the total body weight.And five stocking densities were designed at 40, 70, 100, 130, 160 tail /m2.At the end of the feeding trial, the giant salamander were weighted and measured by batch for the determination of weight gain rate (WGR), special growth rate (SGR), condition factor ( CF) and feed conversion ratio ( FCR) which we used to comprehensive evaluation the effects of stocking density and feed -ing rate on the growth of giant salamander.The results showed that: The suitable stocking density of 1 year old giant sala-mander was 70 tail/m2 , special growth rate of which was significantly higher than that of the group of 160 tail/m2; The suitable feeding rate of 1 year old giant salamander was 2.00%, weight gain rate and special growth rate of which was sig-nificantly higher than the group of 3.00%.

  15. Impact of early feeding patterns for infant obesity under 1 years old%早期喂养方式对1岁以下婴幼儿肥胖的影响

    Institute of Scientific and Technical Information of China (English)

    何杏燕; 陈维; 区素梅

    2014-01-01

    目的:探讨早期喂养方式对1岁以下婴幼儿肥胖的影响。方法对462例1岁以下婴幼儿的体格发育资料进行回顾性调查分析,以0~4个月喂养方式的不同分为母乳喂养组298例和人工喂养组164例,比较两组婴幼儿在不同月龄的肥胖及超重+肥胖的发生率。结果两组在月龄为3个月、6个月时的肥胖率和超重+肥胖率比较差异均无统计学意义(P>0.05);在9、12个月时,母乳喂养组的肥胖率和超重+肥胖率均较之人工喂养低,两组比较差异有统计学意义(P<0.05)。结论给予母乳喂养能够预防出现婴幼儿的早期超重和肥胖症,具有显著的保护作用。%Objective To investigate the impact of early feeding patterns for infant obesity under 1 years old. Methods Physical growth data of 462 cases infants under 1 year old was investigated and analyzed retrospectively. The infants were divided into breastfeeding group 298 cases and artificial feeding group 164 cases,according to the different ways of feeding from 0 to 4 months. Obesity, overweight and obesity incidence at different age of both groups were then observed and compared. Results Obesity, overweight rate and obesity rate at the age of 3 months and 6 months of both groups had no statistical significance(P > 0.05). At the age of 9 months and 12 months, obesity, overweight rate and obesity rate of breastfeeding group were lower than artificial feeding group. The difference had statistical significance by comparison(P < 0.05). Conclusion Breastfeeding can prevent the emergence of early infant overweight and obesity, which had significant protective effect.

  16. Influencia da crioterapia e da elevação no edema induzido pelo dextrano na pata posterior de rato

    OpenAIRE

    Vanessa Monteiro Pedro

    1990-01-01

    Resumo: Os resultados deste trabalho mostraram que a crioterapia local associada à elevação reduziu o edema induzido pelo dextrano na pata posterior de rato. A crioterapia aplicada na pata contralateral, associada à elevação, provocou diminuição temporária do edema. Os recursos terapêuticos utilizados apresentaram- se mais efetivos quando aplicados durante 1 hora do que durante 30 minutos, principalmente nos animais tratados com crioterapia local. Estes resultados sugerem que a crioter...

  17. Saber morir. Antropología de la muerte y relatos de psicópatas en el cine.

    OpenAIRE

    Sánchez-Biosca, Vicente

    1995-01-01

    El presente texto estudia la relación existente entre la antropología de la muerte y los relatos de psicópatas. Partiendo de una concepc8ión del relato que se inspira de Walter Benjamin y se materializa en las formas de continuidad, serialidad, ciclismo y final, pone en relación los rasgos formales de los nuevos relatos de psicópatas en el cine de los años 80 en adelante con el imaginario científico de la postmodernidad.

  18. 0~1岁婴儿出生缺陷的流行病学调查%Epidemiological survey on 0-1 years old baby with birth defect

    Institute of Scientific and Technical Information of China (English)

    倪少义; 何洁壁; 陈少娜; 吴翔; 蔡幸生; 黄伟鹏; 王榕生; 洪艳苹; 倪少英; 卢晓航

    2012-01-01

    Objective To understand the incidence of birth defect in 0-1 years old baby in some regions of Jieyang, then to determine the focus groups for prevention. So that it can provide a foundation for birth defect prevention, pre-pregnancy and pregnancy care. Methods Those babies, who were born in Jiedong County, Puning City and Rongcheng District from March 3, 2011 to May 2, 2012 were surveyed by general investigation. Birth defect based on clinical diagnosis, its entity and statistical standard referred to the regulations of International Centre on Birth Defects and Prematurity. Results 238 cases of birth defect babies were found out of 10 773 cases of monitored new babies. The top five diseases of baby birth defects were congenital heart disease, talipes equinovarus, polydactyly, cleft lip and palate and fetal-edematous-syndrome. Some babies had higher incidence of birth defects, such as baby boy, low birth weight baby, and those babies whose mother did not take folic acid, vitamin and trace elements during pregnancy and whose family members smoking and excessive drinking (P < 0.05). Conclusion The incidence rate of birth defects in 0-1 years old baby is 220.92 per ten thousand in some regions of Jieyang City. It is slightly higher than the national average, so it needs attention from each side. Strengthening propaganda and education, screening and preventing birth defects are matters of great urgency.%目的 了解揭阳部分地区0~1岁婴儿出生缺陷的发病情况,确定预防的重点人群,为出生缺陷的预防和孕前、孕期保健提供依据.方法 采用普查的方式,对揭东县、普宁市、榕城区三地2011年3月3日~2012年5月2日出生的婴儿进行调查.出生缺陷以临床诊断为依据,病种及统计标准参照国际出生缺陷监测情报交换所的规定.结果 共监测10 773名婴儿,发现出生缺陷238例;婴儿出生缺陷排名前5位的疾病分别是先天性心脏病、马蹄内翻足、多指(趾)、唇(腭)裂

  19. Study on Winter Survival of the 1-year-old Seedlings of 19 Landscaping Tree Species%19种园林绿化树木1年生播种苗越冬研究

    Institute of Scientific and Technical Information of China (English)

    马晓辉; 刘燕; 王良民

    2012-01-01

    In this experiment, freezing injuries in winter for the 1-year-old seedlings of 19 landscaping tree species common in the central Shanxi were compared to examine the winter survival ability of landscaping tree seedlings and to provide a practical reference guide for seedling propagation in the area. The results indicated: (1) the 1-year-old seedlings of Acer mono, Platycladus orientalis, Fraxinus pennsylvanica, Euonymus bungeanus, Koelreuteria paniculata, Gleditsia japonica, Syringa reticulata and Ligustrum obtusifolum could safely survive winter in the area, without or with little freezing injuries. Seedling propagation was appropriate for these species in the area. (2) The seedlings of Firmiana simplex and Hibiscus syriacus suffered most serious freezing injuries, resulting in very low survival rates despite under protection in the winter. Seedling propagation was not appropriate for the two species in the area. (3) The seedlings of Cornus alba, Albizia julibrissin, Pterocarya stenoptera, Acer negundo, Platanus acerifolia, Cercis chinensis, Toona sinensis, Lagerstroemia indica and Catalpa bungei suffered varying degrees of freezing injuries and needed to be observed in the second even third winters to decide if seedling propagation was appropriate for these species in this area. (4) The freezing injury index with properly weighted class 4 could more objectively reflect and compare freezing injuries of the different tree seedlings. The results from this study could provide a practical reference guide for seedling propagation of the 19 species in the area.%为了检测山西中部园林绿化树种播种苗的越冬特性,进而为苗木培育提供实用参考依据,对19种山西中部地区常见的园林绿化树种的1年生播种苗进行了越冬受冻害比较研究.结果表明:(1)五角枫、侧柏、洋白蜡、丝棉木、栾树、山皂荚、暴马丁香和水蜡的1年生播种苗可以在该地区安全越冬,不受冻害影响或受冻害影响很

  20. Prediction function of early BMI increment to overweight of 1 year old infants%早期BMI增量对1岁婴幼儿超重的预测作用

    Institute of Scientific and Technical Information of China (English)

    乔永涛; 齐秀花; 张茜; 王明园; 刘杰

    2015-01-01

    Objective To analyze influencing factors of overweight and obesity in infancy.Methodsanalyze medical m anual of 533 infants in our hospital including height, weight, feeding history and anemia status.ResultsBMI value of 1 year o ld baby boys and girls showed statistical significance. Anemia is one of influence factors of overweight at age of 6 months and 9 months. Through logistics regression analysis, BMI increment of 0~3 months and 3-6 months is one of influence factors of over weight at 1 year old. ConclusionAnemia at age of 6 months and 9 months is one of influence factors of overweight or obesity , and growing fast is the risk factor for the overweight and obesity at early infancy.%目的:分析婴儿期超重及肥胖的影响因素。方法对在我院建立体检手册的533名婴儿的身高、体重、喂养史、是否存在贫血等进行分析。结果男婴与女婴在1岁时的BMI值具有统计学差异,在6个月或9个月时存在贫血是1岁时超重的影响因素,经logistics回归分析,0~3个月及3~6个月的BMI值增量是1岁时超重的影响因素。结论6个月或9个月患有贫血是婴幼儿超重及肥胖的危险因素,早期的快速增长是其危险因素。

  1. PatA and PatB form a functional heterodimeric ABC multidrug efflux transporter responsible for the resistance of Streptococcus pneumoniae to fluoroquinolones.

    Science.gov (United States)

    Boncoeur, Emilie; Durmort, Claire; Bernay, Benoît; Ebel, Christine; Di Guilmi, Anne Marie; Croizé, Jacques; Vernet, Thierry; Jault, Jean-Michel

    2012-10-02

    All bacterial multidrug ABC transporters have been shown to work as either homodimers or heterodimers. Two possibly linked genes, patA and patB from Streptococcus pneumococcus, that encode half-ABC transporters have been shown previously to be involved in fluoroquinolone resistance. We showed that the ΔpatA, ΔpatB, or ΔpatA/ΔpatB mutant strains were more sensitive to unstructurally related compounds, i.e., ethidium bromide or fluoroquinolones, than the wild-type R6 strain. Inside-out vesicles prepared from Escherichia coli expressing PatA and/or PatB transported Hoechst 33342, a classical substrate of multidrug transporters, only when both PatA and PatB were coexpressed. This transport was inhibited either by orthovanadate or by reserpine, and mutation of the conserved Walker A lysine residue of either PatA or PatB fully abrogated Hoechst 33342 transport. PatA, PatB, and the PatA/PatB heterodimer were purified from detergent-solubilized E. coli membrane preparations. Protein dimers were identified in all cases, albeit in different proportions. In contrast to the PatA/PatB heterodimers, homodimers of PatA or PatB failed to show a vanadate-sensitive ATPase activity. Thus, PatA and PatB need to interact together to make a functional drug efflux transporter, and they work only as heterodimers.

  2. PATA METAR

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — METAR is a routine scheduled observation and is the primary observation code used in the United States to satisfy requirements for reporting surface meteorological...

  3. Overexpression of patA and patB, which encode ABC transporters, is associated with fluoroquinolone resistance in clinical isolates of Streptococcus pneumoniae.

    Science.gov (United States)

    Garvey, Mark I; Baylay, Alison J; Wong, Ryan L; Piddock, Laura J V

    2011-01-01

    Fifty-seven clinical isolates of Streptococcus pneumoniae were divided into four groups based on their susceptibilities to the fluoroquinolones ciprofloxacin and norfloxacin and the dyes ethidium bromide and acriflavine. Comparative reverse transcription-PCR was used to determine the level of expression of the genes patA and patB, which encode putative ABC transporters. Overexpression was observed in 14 of the 15 isolates that were resistant to both fluoroquinolones and dyes and in only 3 of 24 of those resistant to fluoroquinolones only. Isolates overexpressing patA and patB accumulated significantly less of the fluorescent dye Hoechst 33342 than wild-type isolates, suggesting that PatA and PatB are involved in efflux. Inactivation of patA and patB by in vitro mariner mutagenesis conferred hypersusceptibility to ethidium bromide and acriflavine in all isolates tested and lowered the MICs of ciprofloxacin in the patAB-overproducing and/or fluoroquinolone-resistant isolates. These data represent the first observation of overexpression of patA and patB in clinical isolates and show that PatA and PatB play a clinically relevant role in fluoroquinolone resistance.

  4. HetF and PatA control levels of HetR in Anabaena sp. strain PCC 7120.

    Science.gov (United States)

    Risser, Douglas D; Callahan, Sean M

    2008-12-01

    Anabaena sp. strain PCC 7120 is a filamentous cyanobacterium that differentiates heterocysts in response to deprivation of combined nitrogen. A hetF deletion strain lacked heterocysts and had aberrant cell morphology. Site-directed mutagenesis of the predicted active-site histidine and cysteine residues of this putative caspase-hemoglobinase fold protease abolished HetF function, supporting the hypothesis that HetF is a protease. Deletion of patA, which is necessary for the formation of most intercalary heterocysts, or hetF resulted in an increase in HetR protein, and extra copies of hetF on a plasmid functionally bypassed the deletion of patA. A hetR-gfp translational fusion expressed from an inducible promoter demonstrated that hetF-dependent downregulation of HetR levels occurs rapidly in vegetative cells, as well as developing heterocysts. "Mosaic" filaments in which only one cell of a filament had a copy of hetR or hetF indicated that hetF is required for differentiation only in cells that will become heterocysts. hetF was required for transcription from a hetR-dependent transcription start point of the hetR promoter and induction of transcription from the patS promoter. The inverse correlation between the level of HetR protein and transcription from hetR-dependent promoters suggests that the transcriptional activity of HetR is regulated by HetF and PatA.

  5. Effects of different grasses between rows of apple trees on soft characteristics of 1-year-old orchard%行间种植不同草种对幼龄苹果园土壤特性的影响

    Institute of Scientific and Technical Information of China (English)

    寇建村; 杨文权; 程国亭; 韩明玉

    2012-01-01

    于苹果园建植第一年春季,果树行间分别种植不同草种,以清耕的土壤为对照,研究果园土壤温度、含水量、pH值、有机质及N、P、K的变化.结果表明,种草后,夏季高温时土壤温度降低、日变幅减小,含水量增加,生长季结束时,果园土壤pH下降,碱解N、全N、速效P、全P、有机质含量增加,而除种植红三叶的土壤速效K显著(P<0.05)升高外,其余处理全K、速效K均无显著变化;种草后对不同深度土壤肥力的影响不同,马蹄金对土壤N、P和狗牙根与高羊茅对有机质的影响在0~20cm内表现一致,而种植多年生黑麦草、狗牙根、紫羊茅的0~10cm土壤碱解N、全N、全P和种植红三叶、紫军茅的0~10cm土壤有机质升高幅度较10-20cm大,多年生黑麦草、高羊茅、紫羊茅、红三叶、白三叶的速效P,红三叶和高羊茅的碱解N、全N,马蹄金、多年生黑麦草、白三叶的土壤有机质0~10cm土壤升高幅度较10~20cm小,白三叶10~20cm土壤碱解N增加幅度较0~10cm小,全N则反之;草种不同对土壤作用不一,马蹄金对土壤肥力改善作用最大,红三叶、白三叶次之,而狗牙根、高羊茅较差.说明种草后可改善土壤性状,而草种是影响果园种草效益的关键因素.%An experiment was conducted to study the effect of the orchard-grown grasses, planted between the the tows of apple tree in the spring of the 1-year-old apple orchard, on soil temperature, soil water content, pH, organic matter, nitrogen (N) content, phosphorus (P) content, kalium (K) content in October. The clean soil was taken as the control. The results showed that there was a decrease of soil temperature and its daily variance in summer. And soil pH decreased while soil water content, available N and P, total N and P, and organic matter increased. However, available and total K did not change significantly with the exception of available K of soil Trifolium pratense grew in

  6. Structural basis for selective recognition of acyl chains by the membrane-associated acyltransferase PatA.

    Science.gov (United States)

    Albesa-Jové, David; Svetlíková, Zuzana; Tersa, Montse; Sancho-Vaello, Enea; Carreras-González, Ana; Bonnet, Pascal; Arrasate, Pedro; Eguskiza, Ander; Angala, Shiva K; Cifuente, Javier O; Korduláková, Jana; Jackson, Mary; Mikušová, Katarína; Guerin, Marcelo E

    2016-03-11

    The biosynthesis of phospholipids and glycolipids are critical pathways for virtually all cell membranes. PatA is an essential membrane associated acyltransferase involved in the biosynthesis of mycobacterial phosphatidyl-myo-inositol mannosides (PIMs). The enzyme transfers a palmitoyl moiety from palmitoyl-CoA to the 6-position of the mannose ring linked to 2-position of inositol in PIM1/PIM2. We report here the crystal structures of PatA from Mycobacterium smegmatis in the presence of its naturally occurring acyl donor palmitate and a nonhydrolyzable palmitoyl-CoA analog. The structures reveal an α/β architecture, with the acyl chain deeply buried into a hydrophobic pocket that runs perpendicular to a long groove where the active site is located. Enzyme catalysis is mediated by an unprecedented charge relay system, which markedly diverges from the canonical HX4D motif. Our studies establish the mechanistic basis of substrate/membrane recognition and catalysis for an important family of acyltransferases, providing exciting possibilities for inhibitor design.

  7. Avaliação da qualidade de amostras comerciais de boldo (Peumus boldus Molina, pata-de-vaca (Bauhinia spp. e ginco (Ginkgo biloba L. Control quality evaluation of commercial samples of boldo (Peumus boldus Molina, pata-de-vaca (Bauhinia spp. and ginkgo (Ginkgo biloba L.

    Directory of Open Access Journals (Sweden)

    J. G. de Melo

    2004-01-01

    Full Text Available O presente trabalho procurou avaliar a qualidade de produtos comercializados à base de boldo, pata-de-vaca e ginco, através dos parâmetros contidos na Farmacopéia Brasileira e na literatura específica. Foram analisadas oito amostras de boldo, nove de pata-de-vaca e sete de ginco, adquiridas em farmácias na cidade do Recife. A metodologia consistiu em avaliar: os rótulos e bulas dos produtos verificando se estavam de acordo com a RDC n o 17 de 24/02/2000 e a portaria 110/97 da ANVISA; realizar análise sensorial; verificar a autenticidade das amostras e sua pureza. Todas as embalagens de boldo, pata-de-vaca e seis de ginco continham erros ou ausência de informações científicas, além da falta de bula. Na verificação de impurezas, todas as de boldo, cinco de pata-de-vaca, e uma amostra de ginco foram reprovadas. Todos os produtos analisados apresentaram alguma irregularidade segundo os códigos oficiais, sendo necessário uma maior intensificação na vigilância de produtos à base de plantas medicinais no Brasil.This study aimed to evaluate the quality of commercial products prepared with boldo (Peumus boldus Molina, pata-de-vaca (Bauhinia spp. and ginkgo (Ginkgo biloba L. by using parameters from the Brazilian Pharmacopoeia and specific literature. Eight samples of "boldo", nine of "pata-de-vaca", and seven of ginkgo were analyzed, all bought from pharmacies in Recife (Pernambuco, Brazil. The methodology consisted in evaluating the products’ labels and instructions to verify their accordance to RDC n o 17 of 02/24/2000 and ANVISA (National Sanitary Surveillance Agency decree 110/97, undertaking a sensorial analysis, and verifying the authenticity and purity of the samples. All of the packages of "boldo" and "pata-de-vaca" and six of the packages of ginkgo contained mistakes or lacked scientific information; instructions were also missing. After analyzing for impurities, all samples of "boldo", five of "pata-de-vaca", and one of

  8. The Stain That Gets Increasingly Visible. The Ethnic Segregation in the Pata Rât (Stain snout Ghetto, Cluj-Napoca

    Directory of Open Access Journals (Sweden)

    Viorel Mionel

    2012-04-01

    Full Text Available This paper presents, in the first part, a brief theoretical analisys of the ethnic segregation and the causes entailing this kind of urban fragmentation. Undoubtedly, discrimination is one of the main reasons of segregation, closely followed by the countless social disadvantages. Besides all these, we may point out the poor quality of public policies which instead of improving the marginalized people’s situaion, pushes them deeper into poverty and stigma, as in the case study of Pata Rât, Cluj-Napoca. This paper aims at drawing attention to discrimination and segregation of the Gypsy people living in the outskirts of Cluj-Napoca city, usually called Pata Rât ghetto, and the urgent need for new inclusion policies.

  9. Quetotaxia de las patas de Neoppia discreta Ruiz, Mínguez et Subías, 1988 (Acari, Oribatida, Oppiidae, Antilloppiinae

    Directory of Open Access Journals (Sweden)

    Arillo, A.

    1998-12-01

    Full Text Available In this paper the chaetotaxy of the legs of a member of the subfamily Antilloppiinae (Neoppia discreta Ruiz, Mínguez et Subías, 1988 is studied for the first time.En el presente trabajo se realiza por primera vez el estudio de la quetotaxia de las patas de un miembro de la subfamilia Antilloppiinae, Neoppia discreta Ruiz, Mínguez et Subías, 1988.

  10. PSICÓPATAS INTEGRADOS/SUBCLÍNICOS EN LAS RELACIONES DE PAREJA: PERFIL, MALTRATO PSICOLÓGICO Y FACTORES DE RIESGO

    Directory of Open Access Journals (Sweden)

    José Manuel Pozueco Romero

    2013-01-01

    Full Text Available En la presente revisión teórica analizamos las posibles relaciones entre la psicopatía subclínica y las diversas manifestaciones de maltrato psicológico en las relaciones íntimas. Para ello es preciso delimitar el concepto de psicopatía subclínica, así como también la problemática del maltrato psicológico en la pareja, también denominado violencia emocional y/o violencia invisible, puesto que es el tipo de maltrato que mayormente perpetran las parejas psicópatas en sus relaciones, todo lo cual nos permitirá ofrecer un conjunto de indicadores para concretar un perfil no psicopatológico del agresor psicópata en la pareja. Delimitamos el perfil general del psicópata integrado en la pareja, así como también el tipo de relaciones íntimas que suelen establecer y los indicadores de maltrato psicológico que representan factores de riesgo de la relación. Finalmente, también revisamos las posibles relaciones entre esos indicadores y los rasgos psicopáticos.

  11. Reduced blood clearance and increased urinary excretion of N-nitrosodimethylamine in patas monkeys exposed to ethanol or isopropyl alcohol.

    Science.gov (United States)

    Anderson, L M; Koseniauskas, R; Burak, E S; Moskal, T J; Gombar, C T; Phillips, J M; Sansone, E B; Keimig, S; Magee, P N; Rice, J M

    1992-03-15

    Low concentrations of N-nitrosodimethylamine are metabolized in rodent and human liver by cytochrome P450IIE1, an activity competitively inhibitable by ethanol. In rodents coadministration of ethanol with N-nitrosodimethylamine results in increased tumorigenicity in extrahepatic organs, probably as a result of reduced hepatic clearance. To test this concept in a primate, the effects of ethanol cotreatment on the pharmacokinetics of N-nitrosodimethylamine were measured in male patas monkeys. Ethanol, 1.2 g/kg given p.o. before i.v. N-nitrosodimethylamine (1 mg/kg) or concurrently with an intragastric dose resulted in a 10-50-fold increase in the area under the blood concentration versus time curves and a 4-13-fold increase in mean residence times for N-nitrosodimethylamine. Isopropyl alcohol, 3.2 g/kg 24 h before N-nitrosodimethylamine, also increased these parameters 7-10-fold; this effect was associated with persistence of isopropyl alcohol and its metabolic product acetone, both IIE1 inhibitors, in the blood. While no N-nitrosodimethylamine was detected in expired air, trace amounts were found in urine. Ethanol and isopropyl alcohol pretreatment increased the maximum urinary N-nitrosodimethylamine concentration 15-50-fold and the percentage of the dose excreted in the urine by 100-800-fold. Thus ethanol and isopropyl alcohol greatly increase systemic exposure of extrahepatic organs to N-nitrosodimethylamine in a primate.

  12. Aprovechamiento de Patas de Pollos como Alternativa para disminuir Residuos Generados en los Mataderos Use of Chicken Feet as an Alternative to the reduce Wastes from Slaughterhouse

    Directory of Open Access Journals (Sweden)

    Poliana F Almeida

    2012-01-01

    Full Text Available Se presenta un estudio sobre la producción de jaleas y gelatinas a partir de las patas de pollo, usualmente producidas como desechos de los mataderos de aves. La investigación se llevó a cabo en dos etapas. En la primera etapa, las jaleas se obtuvieron a partir de las patas del pollo y se evaluaron sus cualidades sensoriales para verificar su aceptabilidad. En la segunda etapa, se produjo gelatinas y se analizó también sus cualidades sensoriales para comprobar su aceptabilidad. Los resultados mostraron que la mayoría de los catadores aprobaron los productos con más de 7 puntos en la escala hedónica y más del 80% dijeron que consumirían los productos. Los niveles de proteínas en las jaleas y gelatinas de patas de pollo superaron en cuatro veces los niveles de los productos comerciales, lo que indica una superioridad con respecto a las calidades químicas y potencialmente medicinales.A study on the production of jelly and gelatin from chicken feet, produced as wasted from chicken slaughterhouse is presented. The study was conducted in two parts. In the first part, jellies were produced from chicken feet and sensory quality was done to verify their acceptability. In the second step, gelatins were elaborated from chicken feet and also subjected to sensory analysis. Results showed that most experts in the panel accepted the products with more than 7 points in the hedonic scale and 80% said that they would consume these chicken products. Gelatin and jelly protein contents were four times larger than commercial products, indicating superiority in their chemistry and potential medicinal qualities.

  13. pata Terminal Aerodrome Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TAF (terminal aerodrome forecast or terminal area forecast) is a format for reporting weather forecast information, particularly as it relates to aviation. TAFs are...

  14. Determination of normal reference ranges for venous blood count among 526 children aging from 1year old to 12 years old in Shanghai%上海市526例1~12岁儿童静脉血血常规正常参考区间建立

    Institute of Scientific and Technical Information of China (English)

    高原; 邹琛; 蒋婕; 杨剑敏; 田先敏

    2015-01-01

    Objective To determine normal reference ranges for venous blood count among children aging from 1 year old to 12 years old.Methods These normal reference ranges were defined in a population of 526 healthy children who had no blood system diseases,allergic diseases,respiratory system diseases,urinary system diseases,digestive system disease,rheumatoid disease,thyroid disease,parasitic infections,malignancies and genetic disease,etc.Values of white blood cell count (WBC),red blood cell count (RBC),hemoglobin (Hb)concentration,red blood cell specific volume (Hct),mean corpusular volume(MCV),mean cell hemoglo-bin (MCH),mean corpuscular hemoglobin(MCHC),platelet (PLT),percentage of neutrophil (NE%),percentage of lymphocyte (LY%),percentage of mononuclear cells (MO%),percentage of acidophilic granulocyte (EOS%).Statistical analysis was done on various parameters that we recorded,and then for every parameter,we could get the various reference ranges for different age groups.Results The subjects were divided into 4 groups based on age.Besides the parameters of WBC count and classification of WBC,the rest of parameters were proved to be of no statistical difference between 4 groups..After an integration of the values,we could get the results as follows:RBC(4.02-5.2)×10 1 2/L,HGB 108-144 g/L,Hct 35.2%-40.4%,MCV 74.6-89.9 fL,MCH 20.9-34.7 pg,MCHC 332- 340 g/L,PLT(157 - 409 )× 10 9/L.WBC count did not have statistical difference between the age group 6-0.05),合并后得到 RBC:(4.02~5.2)×1012/L,HGB:108~144 g/L, Hct:35.2%~40.4%,MCV:74.6~89.9 fL,MCH:20.9~34.7 pg,MCHC:332~340 g/L,PLT:(157~409)×109/L。WBC 除6~0.05),其余各组间差异有统计学意义(P <0.05),经合并后得到1~<3岁组:(4.88~13.38)×109/L,3~<6岁组:(4.26~11.6)×109/L,6~12岁组:(4.24~10.24)×109/L。WBC 分类结果在不同年龄段差异有统计学意义(P <0.05),1~岁 NE:29%~32%,LY:58%~61%;3~<6岁组 NE:43%~46%,LY:43%~46%;6~<9岁组 NE:49%~52%,LY:38%~40%;9

  15. Valor del rocuronium en la intubación nasotraqueal del niño cardiópata

    Directory of Open Access Journals (Sweden)

    Lincoln de la Parte Pérez

    2002-06-01

    Full Text Available La intubación de la tráquea por vía nasal es un proceder indispensable en el manejo anestésico del niño con cardiopatías congénitas al cual se le realizan procedimientos quirúrgicos. Esta técnica permite el mantenimiento y protección de la vía aérea y facilita una ventilación confiable. La técnica de la intubación en el infante requiere de relajación muscular profunda en un breve período, con un mínimo de repercusión hemodinámica. Aunque la intubación puede lograrse en poco tiempo después de la administración de succinilcolina, su uso se asocia con varios efectos secundarios, algunos de ellos inaceptables en el paciente de alto riesgo. Los agentes relajantes musculares no despolarizantes disponibles habitualmente en nuestro medio demoran mucho y no se emplean para la intubación de la tráquea en la mayoría de los hospitales. La introducción de un nuevo relajante no despolarizante con un inicio de acción breve y efectos hemodinámicos mínimos, soluciona muchas de nuestras dificultades. Se realizó un estudio de las condiciones obtenidas para la intubación de la tráquea en un grupo de niños cardiópatas después de la administración de rocuronium, en dosis promedio de 0,6 mg por kg de peso corporal. El tiempo promedio necesario para obtener una adecuada relajación muscular osciló entre los 60 y 90 s y se necesitaron dosis de mantenimiento a los 30 min como promedio. No se observaron efectos hemodinámicos ni complicaciones atribuibles al uso del relajante muscular.Nasotracheal intubation is an indispensable procedure in the anesthetic management of children with congenital heart defects that undergo surgical procedures. This technique allows to maintain and to protect the airways and facilitates reliable ventilation. The intubation technique in pediatric patients requires deep muscle relaxation in a short period of time, with minimum hemodynamic impact. Though intubation can be performed shortly after the

  16. Representaciones sociales sobre la muerte en un grupo de médicos Alópatas y alternativos 2009 - 2011

    OpenAIRE

    Álvarez Tobos, Luisa Marcela

    2011-01-01

    Introducción. Muerte y medicina son conceptos que siempre han estado ligados ya que la primera podría ser un desenlace dentro de las intervenciones médicas; es posible que el cambio en el paradigma médico influya en el concepto que tienen los médicos sobre la muerte. Objetivo. Determinar la representación social de muerte que tiene un grupo médicos alternativos y alópatas .Diseño y Métodos La investigación para su ejecución implica dos fases; en este trabajo se presenta la fase cuantitativa q...

  17. Synthesis of Biotin Linkers with the Activated Triple Bond Donor [p-(N-propynoylaminotoluic Acid] (PATA for Efficient Biotinylation of Peptides and Oligonucleotides

    Directory of Open Access Journals (Sweden)

    Martina Jezowska

    2012-11-01

    Full Text Available Biotin is an important molecule for modern biological studies including, e.g., cellular transport. Its exclusive affinity to fluorescent streptavidin/avidin proteins allows ready and specific detection. As a consequence methods for the attachment of biotin to various biological targets are of high importance, especially when they are very selective and can also proceed in water. One useful method is Hüisgen dipolar [3+2]-cycloaddition, commonly referred to as “click chemistry”. As we reported recently, the activated triple bond donor p-(N-propynoylaminotoluic acid (PATA gives excellent results when used for conjugations at submicromolar concentrations. Thus, we have designed and synthesized two biotin linkers, with different lengths equipped with this activated triple bond donor and we proceeded with biotinylation of oligonucleotides and C-myc peptide both in solution and on solid support with excellent yields of conversion.

  18. Metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in the patas monkey: pharmacokinetics and characterization of glucuronide metabolites.

    Science.gov (United States)

    Hecht, S S; Trushin, N; Reid-Quinn, C A; Burak, E S; Jones, A B; Southers, J L; Gombar, C T; Carmella, S G; Anderson, L M; Rice, J M

    1993-02-01

    The metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) was examined in the patas monkey, in order to provide further information about NNK metabolic pathways in primates. Female patas monkeys were given i.v. injections of [5-3H]NNK, and metabolites in serum and urine were analyzed by HPLC. Metabolism by alpha-hydroxylation of NNK was rapid and extensive, and the products of this pathway, 4-hydroxy-4-(3-pyridyl)butyric acid and 4-oxo-4-(3-pyridyl) butyric acid, accounted for a relatively large proportion of serum and urinary metabolites at all time points. This is significant because the formation of these products is associated with modification of DNA by NNK. The other major metabolic pathway was carbonyl reduction to 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), which detected both unconjugated and diastereomeric O-glucuronides. One of these glucuronides had been previously identified in rat urine, but the other diastereomer, which was the more prevalent of the two in serum and urine, had not been observed in studies of NNK metabolism in rodents. It was characterized by its spectral properties, by enzymatic hydrolysis to NNAL, and by derivatization of the released NNAL enantiomer with (R)-(+)-alpha-methylbenzylisocyanate. The two NNAL glucuronides accounted for 15-20% of the urinary metabolites in monkeys given 0.1 micrograms/kg NNK, which is similar to a smoker's dose, suggesting their use as dosimeters of NNK exposure in humans. Pharmacokinetic parameters were consistent with those observed in previous studies of nitrosamines, and varied predictably with body weight of five species. The results of this study have provided new insights relevant to assessing human metabolism of NNK.

  19. Psicopatología, crimen violento, cine y realidad: desmontando mitos sobre psicópatas y psicóticos

    Directory of Open Access Journals (Sweden)

    José Manuel Pozueco Romero

    2015-08-01

    Full Text Available Psicosis, esquizofrenia, paranoia, personalidad múltiple y otro sinfín de términos son los que parecen coincidir con los conceptos coloquiales y peyorativos de locos, tarados, etc. Según numerosos autores, parece ser que la psicosis es la enfermedad mental más grave que existe, y, también, es evidente la cantidad de veces que ha sido (mal utilizada para recrear centenares de películas; el ejemplo más claro de esto mismo lo tenemos en el famoso film de Alfred Hitchcock, Psicosis, que analizamos aquí desde una perspectiva psicológico-forense y criminológica. Por otra parte, el tópico de la psicopatía también ha venido siendo amplia y erróneamente abordado por los medios de comunicación, y mal caracterizado en numerosas películas y series televisivas, todo esto a pesar de que hoy día se trata de un constructo clínico-forense válido y fiable. La relación de la psicopatía con la violencia y la criminalidad es bastante conocida, si bien este aspecto también requiere de una serie de rigurosos matices. En este artículo trataremos de desmontar el mito generalizado de que los enfermos mentales son muy peligrosos, y de que su criminalidad se ciñe exclusivamente a los homicidios, algo que también extienden muchos autores al caso de los psicópatas.

  20. Efeitos do alfa-tocoferol nas lesões de isquemia-reperfusão induzidas em pata direita de ratos

    Directory of Open Access Journals (Sweden)

    Bitu-Moreno José

    2001-01-01

    Full Text Available Recentes estudos demonstraram que os radicais livres de oxigênio parecem desempenhar papel importante nas lesões de isquemia-reperfusão. O alfa-tocoferol(AT age in vivo como um anti-oxidante. Nosso objetivo foi o de verificar se o AT atenuava as lesões de isquemia-reperfusão em pata direita de ratos. Os animais, randomizados, foram divididos nos seguintes grupos(G: G1-controle sem isquemia; G2 e G3 - quatro horas isquemia e duas reperfusão. Os animais do G2 foram tratados com salina e os do G3 com AT, 50mg/kg. Como parâmetros examinamos as alterações de volume e circunferência do pé direito ao longo do experimento, assim como a captação de 99mTc-pirofosfato e a microscopia eletrônica de transmissão do músculo soleus direito. Os aumentos de volume e circunferência do pé dos animais do G2 foram estatisticamente maiores quando comparados com o G1. As medidas do G3 não diferiram do G1. A captação de 99mTc-pirofosfato foi bem aumentada nos G2 e G3, quando comparados ao G1, porém sem diferenças entre os grupos isquêmicos. As lesões ao MET foram menos intensas em três animais do G3, quando comparados ao G2. Conclusão: O tratamento com AT diminuiu a formação do edema mas só protegeu parcialmente as células musculares contra as lesões de isquemia-reperfusão.

  1. Mecanismos envolvidos no efeito modulatório de citocinas pró-inflamatórias sobre as respostas mediadas pelos receptores B1 e B2 para as cininas na pata de rato.

    OpenAIRE

    Campos, Maria Martha

    2001-01-01

    Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Farmacologia. Estudo do efeito do tratamento local com [citocinas pró-inflamatórias] sobre as respostas mediadas pelos [receptores B1 e B2] para as [cininas] na [pata de rato]. O tratamento com as citocinas [IL-1b] ou [TNFa] foi capaz de induzir um aumento dose-dependente e marcante da [resposta edematogênica] mediada pelos receptores B1, acompanhado de um aumento na [expr...

  2. Artificial grammar learning by 1-year-olds leads to specific and abstract knowledge.

    Science.gov (United States)

    Gomez, R L; Gerken, L

    1999-03-01

    Four experiments used the head-turn preference procedure to assess whether infants could extract and remember information from auditory strings produced by a miniature artificial grammar. In all four experiments, infants generalized to new structure by discriminating new grammatical strings from ungrammatical ones after less than 2 min exposure to the grammar. Infants acquired specific information about the grammar as demonstrated by the ability to discriminate new grammatical strings from those with illegal endpoints (Experiment 1). Infants also discriminated new grammatical strings from those with string-internal pairwise violations (Experiments 2 and 3). Infants in Experiment 4 abstracted beyond specific word order as demonstrated by the ability to discriminate new strings produced by their training grammar from strings produced by another grammar despite a change in vocabulary between training and test. We discuss the implications of these findings for the study of language acquisition.

  3. Solar urticaria in a 1-year-old infant: diagnosis and management

    Science.gov (United States)

    Hochstadter, Elana Fay; Ben-Shoshan, Moshe

    2014-01-01

    Solar urticaria is a type of inducible urticaria triggered by sun exposure resulting in hives on exposed skin as well as risk of developing systemic symptoms. Most cases are reported in the adult population. However, cases do occur in children. We present a case of visible light induced urticaria in a 12-month-old girl that demonstrates the need for accurate diagnosis and appropriate management. PMID:24744064

  4. [Maternal perception of her child's weight and unrelated children less than 1 year old].

    Science.gov (United States)

    Flores-Peña, Yolanda; Aguado-Barrera, Miguel E; Cerda-Flores, Ricardo M; Cortés-Gutiérrez, Elva I; Dávila-Rodríguez, Martha I

    2016-11-01

    To evaluate the maternal perception of their child's weight (MPCW) and perception of unrelated children's weight. Cross-sectional. Maternal and Child Nursing Health Department at 6 Units of Family Medicine. 486 dyads (mother and child under 1 year). The following question was applied: "I think my child is", and images were provided according the child's gender. Children's weight and height were measured. A total of 20.5% of the mothers of overweight (OW) children accurately perceived this situation, while none of the mothers of obese (OB) children did (κ=0.14±0.03, Z=5.36, p=.001). By images, 63.3% of mothers of OW children and 33.3% of mothers of OB children perceived this situation (κ=0.01±0.02, Z=0.73, p=.46). Most mothers selected the image of OW child as the image of a healthy child (κ=-0.04±0.01, Z=-2.65, p=.008), the image of a child under 1 year (κ=-0.01±0.02, Z=-0.86, p=.38) and the image that they would like their child to look like (κ=0.0004±0.01, Z=0.02, p=.98). The mothers do not perceive the OW-OB of their children. Copyright © 2015 Elsevier España, S.L.U. All rights reserved.

  5. Predictors of Parent Responsiveness to 1-Year-Olds At-Risk for Autism Spectrum Disorder

    Science.gov (United States)

    Kinard, Jessica L.; Sideris, John; Watson, Linda R.; Baranek, Grace T.; Crais, Elizabeth R.; Wakeford, Linn; Turner-Brown, Lauren

    2017-01-01

    Parent responsiveness is critical for child development of cognition, social-communication, and self-regulation. Parents tend to respond more frequently when children at-risk for autism spectrum disorder (ASD) demonstrate stronger social-communication; however, it is unclear how responsiveness is associated with sensory characteristics of children…

  6. PREDICTORS OF EMOTIONAL AND BEHAVIORAL PROBLEMS IN 1-YEAR-OLD CHILDREN: A LONGITUDINAL PERSPECTIVE.

    Science.gov (United States)

    Sirvinskiene, Giedre; Zemaitiene, Nida; Jusiene, Roma; Markuniene, Egle

    2016-07-01

    Emotional and behavioral problems at an early age can reasonably be considered a high-risk factor for later mental health disorders. The aim of the article is to reveal predictive factors of 1½-year-old children's emotional and behavioral problems. The study was a part of a prospective birth-cohort study. The study sample consisted of 172 full-term infants (born during Gestational Weeks 37-42) and their mothers. Emotional and behavioral problems at the age of 1½ years were measured using the Child Behavior Checklist for Ages 1½-5 (T. Achenbach & L. Rescorla, 2000), which was completed by mothers. Emotional and behavioral problems at age of 1½ years were more prevalent in infants born via cesarean section, as compared to infants born vaginally without administration of medication. Newborns' suboptimal functioning after birth, complicated emotional acceptance of pregnancy, a couple's nonsatisfactory relationship during pregnancy, maternal distress during pregnancy and in the first months after childbirth, and inflexible and parent-oriented attitudes toward infant-rearing also predicted children's emotional and behavioral problems independent of sociodemographic factors. Results suggest that biomedical and psychosocial factors which manifest themselves in the prenatal and perinatal periods can have associations with later infant and child mental health. © 2016 Michigan Association for Infant Mental Health.

  7. Adrenocortical and behavioral attunement in parents with 1-year-old infants.

    Science.gov (United States)

    van Bakel, Hedwig J A; Riksen-Walraven, J Marianne

    2008-03-01

    Sethre-Hofstad et al. [2002, Psychoneuroendocrinology 27:731-747] found that behaviorally well-attuned or sensitive parents showed better physiological attunement with their 2- to 4-year-old toddlers' adrenocortical responses to a potentially challenging task than less sensitive parents. In the present study we aimed to replicate this finding in a sample of 83 parents with 15-month-old infants. Parental and infant cortisol responses were assessed using saliva samples collected before and 21 min after the child's confrontation with a stranger and a moving robot. Infant behaviors reflecting distress/uncertainty during the stranger-robot session were rated from videotape. Parental sensitivity was observed during a parent-infant teaching episode. Our findings replicate those of Sethre-Hofstad et al. [2002, Psychoneuroendocrinology 27:731-747] by showing correlated parent-infant cortisol responses for sensitive parents but not for less sensitive parents. Furthermore, sensitive parents cortisol responses were associated with their children's distress/uncertainty during the stranger-robot episode, whereas this was not true for less sensitive parents. Results indicate an important connection between behavior and physiology in parent-infant interactions that deserve more research.

  8. Evidence of Bordetella pertussis infection in vaccinated 1-year-old Danish children

    DEFF Research Database (Denmark)

    von Linstow, Marie-Louise; Pontoppidan, Peter Lotko; von König, Carl-Heinz Wirsing;

    2010-01-01

    %. The apparent high Bordetella pertussis infection rate in Danish infants suggests that the monocomponent PT toxoid vaccine used in Denmark has limited efficacy against B. pertussis infection. A prospective immunization study comparing a multi-component vaccine with the present monocomponent PT toxoid vaccine...

  9. Fatal aortoesophageal fistula caused by button batteryingestion in a 1-year-old child

    DEFF Research Database (Denmark)

    Mortensen, Anette; Hansen, Nikolaj Friis; Schiødt, Ole Mikael

    2010-01-01

    Ingestion of a button battery can result in serious complications if the battery becomes lodged in the esophagus. We report a case of a 14-month-old child who died from exsanguination caused by an aortoesophageal fistula caused by a 20-mm lithium button battery lodged in the esophagus...

  10. Safety of measles-containing vaccines in 1-year-old children.

    Science.gov (United States)

    Klein, Nicola P; Lewis, Edwin; Fireman, Bruce; Hambidge, Simon J; Naleway, Allison; Nelson, Jennifer C; Belongia, Edward A; Yih, W Katherine; Nordin, James D; Hechter, Rulin C; Weintraub, Eric; Baxter, Roger

    2015-02-01

    All measles-containing vaccines are associated with several types of adverse events, including seizure, fever, and immune thrombocytopenia purpura (ITP). Because the measles-mumps-rubella-varicella (MMRV) vaccine compared with the separate measles-mumps-rubella (MMR) and varicella (MMR + V) vaccine increases a toddler's risk for febrile seizures, we investigated whether MMRV is riskier than MMR + V and whether either vaccine elevates the risk for additional safety outcomes. Study children were aged 12 to 23 months in the Vaccine Safety Datalink from 2000 to 2012. Nine study outcomes were investigated: 7 main outcomes (anaphylaxis, ITP, ataxia, arthritis, meningitis/encephalitis, acute disseminated encephalomyelitis, and Kawasaki disease), seizure, and fever. Comparing MMRV with MMR + V, relative risk was estimated by using stratified exact binomial tests. Secondary analyses examined post-MMRV or MMR + V risk versus comparison intervals; risk and comparison intervals were then contrasted for MMRV versus MMR+V. We evaluated 123,200 MMRV and 584,987 MMR + V doses. Comparing MMRV with MMR + V, risks for the 7 main outcomes were not significantly different. Several outcomes had few or zero postvaccination events. Comparing risk versus comparison intervals, ITP risk was higher after MMRV (odds ratio [OR]: 11.3 [95% confidence interval (CI): 1.9 to 68.2]) and MMR + V (OR: 10 [95% CI: 4.5 to 22.5]) and ataxia risk was lower after both vaccines (MMRV OR: 0.8 [95% CI: 0.5 to 1]; MMR + V OR: 0.8 [95% CI: 0.7 to 0.9]). Compared with MMR + V, MMRV increased risk of seizure and fever 7 to 10 days after vaccination. This study did not identify any new safety concerns comparing MMRV with MMR + V or after either the MMRV or the MMR + V vaccine. This study provides reassurance that these outcomes are unlikely after either vaccine. Copyright © 2015 by the American Academy of Pediatrics.

  11. ERP measures of syllable processing in 1 year olds: infant diet- and gender-related differences

    Science.gov (United States)

    Language skills are generally better in females than males, but the basis for these differences has not been determined. To investigate whether variations in infant diet contribute to these differences, cortical responses to the syllable /pa/ (ERPs;124 sites) were examined in healthy 12-month-old, f...

  12. Quantificação de citocinas no soro e homogenato da pata na intoxicação experimental com veneno de Bothropoides jararaca em ratos Wistar tratados com soroterapia e Mikania glomerata

    Directory of Open Access Journals (Sweden)

    Y.P. Motta

    2014-10-01

    Full Text Available O presente estudo teve como objetivo quantificar os níveis de citocinas pró-inflamatórias, entre as quais TNF-α, interleucina-1β (IL-1β, IL-6, e anti-inflamatórias, como IL-10, interferon-γ (INF-γ, bem como comparar o efeito do tratamento convencional com o efeito do tratamento complementado pelo extrato da planta Mikania glomerata, na intoxicação experimental por Bothropoides jararaca. Foram usados ratos Wistar,divididos em três grupos: C - controle, VB - veneno botrópico + soro antiofídico e VBM - veneno botrópico + soro antiofídico + Mikania glomerata. As citocinas foram quantificadas, no soro e no homogenato desses animais, pelo teste ELISA, em três momentos (M1 - 30 minutos, M2 - seis horas e M3 - 24 horas após a inoculação do veneno. Os resultados obtidos evidenciaram que a intoxicação por veneno botrópico estimula principalmente a produção de IL-6 no soro e TNF-α, IL-1β, IL-6 no homogenato da pata de animais experimentalmente intoxicados. O tratamento complementar, com o extrato da planta Mikania glomerata, teve influência principalmente na produção de IL-6, IL-10 e IFN-γ no soro e IL-6, IL-1β e IFN-γ no homogenato. Porém, são necessários novos estudos com o extrato de Mikania glomerata para que se possa entender a ação dessa planta sobre a intoxicação botrópica, bem como verificar qual a melhor via para administrá-lo.

  13. Unexpected dominance of 1 year old parr among migrating salmon and sea trout individuals in the River Siesartis, Lithuania

    Directory of Open Access Journals (Sweden)

    Kęstutis Skrupskelis

    2015-12-01

    However, 1 year age parr unexpectedly dominated among salmon juveniles descending towards the Sea in the restocked Siesartis River, which is situated 400 km to the Baltic Sea. The same phenomenon has been observed among migrating sea trout individuals, too. Mass migration of 1 year age salmon and sea trout parr with mean body length ranging from 69 to 150 mm can hardly be explained by density-dependant regulatory mechanisms alone. Possible impact of particularly long distance migration route is also discussed.

  14. High frequency of S. aureus (MSSA-MRSA) in children under 1 year old with skin and soft tissue infections.

    Science.gov (United States)

    Salazar, Lorena; Quiceno, Judy Natalia Jimenez

    2017-09-20

    Staphylococcus aureus is responsible for a large number of infections in pediatric population; however, information about the behavior of such infections in this population is limited. The aim of the study was to describe the clinical, epidemiological, and molecular characteristics of infections caused by methicillin-susceptible and resistant S. aureus (MSSA-MRSA) in a pediatric population. A cross-sectional descriptive study in patients from birth to 14 years of age from three high-complexity institutions was conducted (2008-2010). All patients infected with MRSA and a representative sample of patients infected with MSSA were included. Clinical and epidemiological information was obtained from medical records and molecular characterization included spa typing, pulsed-field gel electrophoresis (PFGE), and multilocus sequence typing (MLST). In addition, staphylococcal cassette chromosome mec (SCCmec) and virulence factor genes were detected. A total of 182 patients, 65 with MSSA infections and 117 with MRSA infections, were included in the study; 41.4% of the patients being under 1 year. The most frequent infections were of the skin and soft tissues. Backgrounds such as having stayed in day care centers and previous use of antibiotics were more common in patients with MRSA infections (p≤0.05). Sixteen clonal complexes were identified and MSSA strains were more diverse. The most common cassette was SCCmec IVc (70.8%), which was linked to pvl. In contrast with other locations, a prevalence of infections in children under 1 year of age in the city could be observed; this emphasizes the importance of epidemiological knowledge at the local level. Copyright © 2017 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. All rights reserved.

  15. Expression and inducibility of cytochrome P450 isoforms in 1-year-old intrasplenic liver cell transplants in rats.

    Science.gov (United States)

    Lupp, Amelie; Danz, Manfred; Müller, Dieter; Klinger, Wolfgang

    2002-03-01

    Syngenic fetal liver tissue suspensions were transplanted into the spleens of 60- to 90-day-old male Fischer 344 inbred rats. Transplant recipients were compared with age-matched control rats. One year after surgery, the animals were treated orally with beta-naphthoflavone (BNF), phenobarbital (PB), dexamethasone (DEX) or the respective solvents 24 or 48 h before being killed. Expression of cytochrome P450 (P450) isoforms in spleens and orthotopic livers was assessed by immunohistochemistry and P450-dependent monooxygenase functions by the model reactions ethoxyresorufin O-deethylation (EROD), ethoxycoumarin O-deethylation (ECOD), pentoxyresorufin O-depentylation (PROD) and ethylmorphine N-demethylation (EMND). Spleens of control animals displayed almost no expression of P450 isoforms and P450-mediated monooxygenase functions. Similar to liver, in the transplanted hepatocytes no P450 1A1 but distinct P450 2B1 and 3A2 expression was observed. Furthermore, the transplant-containing spleens displayed significant EROD, ECOD, PROD and EMND activities. Similar to normal liver, BNF treatment enhanced P450 1A1 and 2B1, PB induced P450 2B1 and 3A2, and DEX induced P450 3A2 expression in the transplanted hepatocytes. Correspondingly, in the transplant-containing spleens EROD, ECOD and PROD activities were significantly enhanced following BNF treatment, EROD, ECOD, PROD and EMND activities after PB administration, and EMND activity by DEX treatment. These results demonstrate that hepatocytes originating from fetal liver tissue suspensions can survive in the spleen at least for 1 year. They have differentiated into adult hepatocytes and even 1 year after transplantation express different P450 isoforms which are inducible by BNF, PB and DEX, corresponding to normal adult liver.

  16. Time to First Shunt Failure in Pediatric Patients over 1 Year Old: A 10-Year Retrospective Study.

    Science.gov (United States)

    Shannon, Chevis N; Carr, Kevin R; Tomycz, Luke; Wellons, John C; Tulipan, Noel

    2013-01-01

    Studies comparing alternatives to ventriculoperitoneal (VP) shunting for treatment of hydrocephalus have often relied upon data from an earlier era that may not be representative of contemporary shunt survival outcomes. We sought to determine the shunt survival rate of our cohort and compare our results to previously published shunt survival and endoscopic third ventriculostomy (ETV) success rates. We identified 95 patients between 1 and 18 years of age, who underwent initial VP shunt placement between January 2001 and December 2010. Our study shows a shunt survival rate of 85% at 6 months and 79% at 2 years, for initial shunts in pediatric patients over 1 year of age in this cohort. The overall infection rate was 3%. This compares favorably with published success rates of ETV at similar time points as well as with the rate of infection. This suggests that ventricular shunting remains a viable alternative to ETV in the older child.

  17. Combining Genome-Wide Information with a Functional Structural Plant Model to Simulate 1-Year-Old Apple Tree Architecture

    Science.gov (United States)

    Migault, Vincent; Pallas, Benoît; Costes, Evelyne

    2017-01-01

    In crops, optimizing target traits in breeding programs can be fostered by selecting appropriate combinations of architectural traits which determine light interception and carbon acquisition. In apple tree, architectural traits were observed to be under genetic control. However, architectural traits also result from many organogenetic and morphological processes interacting with the environment. The present study aimed at combining a FSPM built for apple tree, MAppleT, with genetic determinisms of architectural traits, previously described in a bi-parental population. We focused on parameters related to organogenesis (phyllochron and immediate branching) and morphogenesis processes (internode length and leaf area) during the first year of tree growth. Two independent datasets collected in 2004 and 2007 on 116 genotypes, issued from a ‘Starkrimson’ × ‘Granny Smith’ cross, were used. The phyllochron was estimated as a function of thermal time and sylleptic branching was modeled subsequently depending on phyllochron. From a genetic map built with SNPs, marker effects were estimated on four MAppleT parameters with rrBLUP, using 2007 data. These effects were then considered in MAppleT to simulate tree development in the two climatic conditions. The genome wide prediction model gave consistent estimations of parameter values with correlation coefficients between observed values and estimated values from SNP markers ranging from 0.79 to 0.96. However, the accuracy of the prediction model following cross validation schemas was lower. Three integrative traits (the number of leaves, trunk length, and number of sylleptic laterals) were considered for validating MAppleT simulations. In 2007 climatic conditions, simulated values were close to observations, highlighting the correct simulation of genetic variability. However, in 2004 conditions which were not used for model calibration, the simulations differed from observations. This study demonstrates the possibility of integrating genome-based information in a FSPM for a perennial fruit tree. It also showed that further improvements are required for improving the prediction ability. Especially temperature effect should be extended and other factors taken into account for modeling GxE interactions. Improvements could also be expected by considering larger populations and by testing other genome wide prediction models. Despite these limitations, this study opens new possibilities for supporting plant breeding by in silico evaluations of the impact of genotypic polymorphisms on plant integrative phenotypes. PMID:28127302

  18. Infotehnoloogia ja virtuaalõpe / Kai Pata

    Index Scriptorium Estoniae

    Pata, Kai

    2001-01-01

    TÜ loodusteaduste didaktika lektoraadis toimus 2000.-2001. a. 160-tunnine koolituskursus "Infotehnoloogia ja loodusteadused" loodusainete (bioloogia, keemia, füüsika) õpetajatele, eesmärgiks tutvustada arvuti ja virtuaalõppe kasutusvõimalusi kooli õppetöös

  19. Determination of effective factors in breast feeding continuity for infants less than 1 year old in urban area of Bushehr Province

    Directory of Open Access Journals (Sweden)

    Zahra Ghaed Mohamamdi

    2004-09-01

    Full Text Available Breast feeding is of great value to mothers and children health. Data shows exclusive breast feeding rate (especially in urban area and continuity of breast feeding in Bushehr is lower than the national rate. In this cross-sectional study, by using cluster random sampling method, mothers of 436 children (213 boys, 223 girls, aged under one year old were selected for face to face interview in Bushehr province. Ninety-nine percent of mothers had started breast feeding immediately after delivery but 80% of infants fewer than 6 months and 62% in the age group of 6-12 months were breast fed exclusively or inclusively. Rate of exclusive breast feeding was 47%. The most common causes of terminating breast feeding were insufficient breast milk, mothers’ occupations and crying of children. There was a significant relation between breast feeding and mother’s education, mother’s job, mother’s knowledge about breast feeding promoting program and mother or child’s illness. However, there was no significant relation between father’s education and his job, the number of living children and breast feeding condition for previous child. Promotion of mother’s knowledge by health and hospital staff during pregnancy and delivery time is the most important factor in increasing breast feeding continuity.

  20. Pathological Anatomy and Quantitative Analysis of morphologic dimensions of 1-Year Old Children Hearts in Case of Sudden Death at Home

    Directory of Open Access Journals (Sweden)

    Yu. R. Yunusova

    2009-06-01

    Full Text Available One hundred twenty-three babies died at home at the age of 1–12 months have been examined from 2004 till 2008. 39 babies died from sudden infant death syndrome (SIDS. The comparison group has been composed of 58 babies of the same age died at home from various diseases. Investigations have been performed in DGCB N1, Samara. About 95 % of babies died from SIDS at home during the first six months of their life, with top mortality between 1 till 3 months. There was sexual difference — 67 % of boys. The majority of home death cases have happened in summer — 49 babies (30%. Morphological investigations have been made including different heart weighting, histological and histometric examination of cardiomyocites. It has been revealed that in the group of babies died from SIDS the most constant symptoms have included: right heart hypertrophy, great heart weight variability, ventricular index.

  1. External Sources of Individual Differences? A Cross-Linguistic Analysis of the Phonetics of Mothers' Speech to 1-Year-Old Children.

    Science.gov (United States)

    Vihman, Marilyn M.; And Others

    1994-01-01

    Sampled the speech of American, French, and Swedish mothers to their one-year olds, to analyze distribution of phonetic parameters of adult speech, as well as children's own early words. Found that variability is greater in child words than in adult speech, and mother-child dyads showed no evidence of specific maternal influence on phonetics of…

  2. The growth pattern of 0-1-year-old Danish children, when screened by public health nurses--the Copenhagen County Child Cohort 2000

    DEFF Research Database (Denmark)

    Olsen, Else Marie; Petersen, Janne; Skovgaard, Anne Mette

    2005-01-01

    Using inadequate growth references when screening child health could lead to false conclusions concerning individual growth. We were concerned that this might apply to the official Danish growth reference.......Using inadequate growth references when screening child health could lead to false conclusions concerning individual growth. We were concerned that this might apply to the official Danish growth reference....

  3. Is early differentiation of human behavior a precursor to the 1-year-old's understanding of intentional action? Comment on Legerstee, Barna, and DiAdamo (2000).

    Science.gov (United States)

    Gergely, G

    2001-09-01

    In a recent issue of Developmental Psychology, M. Legerstee, J. Barna, and C. DiAdamo (2000) reported a study showing that 6-month-olds expect people to talk to persons rather than to inanimate objects and to manipulate inanimates rather than persons. They interpreted this ability as a "precursor" to later understanding of intentionality. The present article takes issue with the authors' 2 different levels of interpretation that contradict each other and raise problems in their own right. It is suggested that M. Legerstee et al.'s finding is most parsimoniously explained by associative learning and may not constitute a precursor to later understanding of intentionality in any well-defined sense of the term. The present article argues for the importance of differentiating between associative and inferential processes and reviews evidence that the understanding of goal-directed action around 9 months of age involves principle-based inferences.

  4. Efeitos metabólicos da L-alanil-glutamina em ratos submetidos à isquemia da pata traseira esquerda seguida de reperfusão Metabolic effects of L-alanyl-glutamine in rats subjected to left hind leg ischemia and reperfusion

    Directory of Open Access Journals (Sweden)

    João Martins de Souza Torres

    2003-01-01

    Full Text Available OBJETIVO: Objetivou-se investigar os efeitos metabólicos da L-alanil glutamina no tecido muscular e sangue arterial de ratos Wistar submetidos à isquemia aguda da pata traseira. MÉTODOS: Utilizaram-se 48 ratos machos distribuídos em 4 grupos (1- controle / 2 - experimento, redistribuídos em 2 subgrupos (n=06. Trinta minutos após a injeção de uma solução a 20% de L-alanil-glutamina (0,75mg/ grupo 2 ou solução salina (grupo 1 na veia jugular direita ocluiu-se a artéria ilíaca comum esquerda por 30 minutos, por pinçamento. Amostras musculares e de sangue arterial foram obtidas logo após a remoção da pinça (tempo 0 e 5, 15 e 30 mais tarde. RESULTADOS: Observou-se redução significativa (p PURPOSE: An experimental study has been conducted to investigate acute ischemic changes in concentrations of glucose, piruvate, lactate and ketone bodies in rat hind leg muscle and arterial blood after intravenous injection of l-alanil-glutamine solution. METHODS: Forty-eight male Wistar rats were distributed into two groups: Group 1 (Control and Group 2 (Experiment. Each group was divided into 4 subgroups (n=6. Thirty minutes after administration of 20% solution of L-alanil-glutamine (0,75g/Kg, group 1 or saline solution (group 2 into right jugular vein, a clamp was placed across left common iliac artery for 30 minutes. Samples from left thigh muscle and arterial blood from abdominal aorta were collected at the end of ischemic period (subgroup 0 and 5, 15 and 30 minutes later. RESULTS: Glucose concentrations were decreased (p<0.05 in experiment group muscles, compared to respective control (subgroup 15 min and significantly increased in subgroups 15 and 30 min as compared to subgroup 0 min. There was no difference in glycemia and pyruvate concentrations when comparing experiment versus control rats. Decreased lactate concentrations might be related to L-alanyl glutamine effects. CONCLUSIONS: Increased availability of L

  5. Tamoxifen-DNA adduct formation in monkey and human reproductive organs.

    Science.gov (United States)

    Hernandez-Ramon, Elena E; Sandoval, Nicole A; John, Kaarthik; Cline, J Mark; Wood, Charles E; Woodward, Ruth A; Poirier, Miriam C

    2014-05-01

    The estrogen analog tamoxifen (TAM), used for adjuvant therapy of breast cancer, induces endometrial and uterine tumors in breast cancer patients. Proliferation stimulus of the uterine endometrium is likely involved in tumor induction, but genotoxicity may also play a role. Formation of TAM-DNA adducts in human tissues has been reported but remains controversial. To address this issue, we examined TAM-DNA adducts in uteri from two species of monkeys, Erythrocebus patas (patas) and Macaca fascicularis (macaque), and in human endometrium and myometrium. Monkeys were given 3-4 months of chronic TAM dosing scaled to be equivalent to the daily human dose. In the uteri, livers and brains from the patas (n = 3), and endometrium from the macaques (n = 4), TAM-DNA adducts were measurable by TAM-DNA chemiluminescence immunoassay. Average TAM-DNA adduct values for the patas uteri (23 adducts/10(8) nucleotides) were similar to those found in endometrium of the macaques (19 adducts/10(8) nucleotides). Endometrium of macaques exposed to both TAM and low-dose estradiol (n = 5) averaged 34 adducts/10(8) nucleotides. To examine TAM-DNA persistence in the patas, females (n = 3) were exposed to TAM for 3 months and to no drug for an additional month, resulting in low or non-detectable TAM-DNA in livers and uteri. Human endometrial and myometrial samples from women receiving (n = 8) and not receiving (n = 8) TAM therapy were also evaluated. Women receiving TAM therapy averaged 10.3 TAM-DNA adducts/10(8) nucleotides, whereas unexposed women showed no detectable TAM-DNA. The data indicate that genotoxicity, in addition to estrogen agonist effects, may contribute to TAM-induced human endometrial cancer.

  6. Psicópatas y asesinos en serie

    OpenAIRE

    Antuña Bellerín, Mª de los Ángeles; Rodríguez Franco, Luís

    2007-01-01

    En este artículo, distinguimos la psicopatía de otros trastornos, como el explosivo intermitente, el disocial o el negativista desafiante, que conllevan comportamientos violentos y que se encuentran recogidos en los manuales diagnósticos al uso. Tras realizar un breve bosquejo de la evolución del término psicopatía, analizamos los problemas que se presentan entre el trastorno antisocial de la personalidad y la psicopatía para centrarnos a continuación en los llamados asesinos en serie. Si bie...

  7. PATAS DE PERRO DE CARLOS DROGUETT: UNA NOVELA PICARESCA

    OpenAIRE

    RODRIGUEZ FERRER ; ROCIO

    2004-01-01

    Carlos Droguett Alfare (Santiago de Chile, 1912 - Berna, Suiza, 1996) es, probablemente, uno de los novelistas chilenos más interesantes y cautivadores y, además, uno de los más coherentes en cuanto a postura ideológica, visión de mundo y escritura se refiere. Su narrativa refleja un carácter unitario, una línea consecuente de verdadero compromiso ético con el hombre. Marcada por cierto pesimismo existencial, la obra de Droguett plantea problemáticas humanas que tienen muc...

  8. PATAS DE PERRO DE CARLOS DROGUETT: UNA NOVELA PICARESCA

    OpenAIRE

    RODRIGUEZ FERRER, ROCIO

    2004-01-01

    Carlos Droguett Alfare (Santiago de Chile, 1912 - Berna, Suiza, 1996) es, probablemente, uno de los novelistas chilenos más interesantes y cautivadores y, además, uno de los más coherentes en cuanto a postura ideológica, visión de mundo y escritura se refiere. Su narrativa refleja un carácter unitario, una línea consecuente de verdadero compromiso ético con el hombre. Marcada por cierto pesimismo existencial, la obra de Droguett plantea problemáticas humanas que tienen mucho de actuales...

  9. El estado periodontal y la higiene bucal en los pacientes cardiópatas del Policlínico “Plaza de la Revolución” The periodontal state and the oral hygiene in cardiopathy patients at “Plaza de la Revolución ” Polyclinic

    Directory of Open Access Journals (Sweden)

    María Elena Pueo Lazo

    2006-09-01

    Full Text Available La enfermedad periodontal se relaciona con las enfermedades cardiovasculares, ya que los microorganismos del surco gingival y de las bolsas periodontales pueden agravar el inicio y curso de estas afecciones cardiovasculares. Se efectuó un estudio descriptivo y transversal, a una muestra no probabilística de 210 cardiópatas del Policlínico "Plaza de la Revolución" en el mes de febrero del 2003, a los que se les aplicó el índice de higiene bucal revisado (IHB-R de Greene y Vermillion, y el índice periodontal revisado de Russell (IP-R. Las variables del estudio fueron: la edad, el sexo, el estado periodontal y el grado de higiene bucal. Se pudo constatar que el 91 % de estos pacientes presentó algún grado de afección periodontal, y fueron los adultos jóvenes los de mayor prevalencia en cuanto a enfermedad gingival crónica, con el 83,3 %. La gravedad de las periodontopatías aumentó con la edad; no hubo diferencias significativas en canto al sexo. Solo el 8 % de estos pacientes tuvo buena higiene bucal; en el grupo estudiado predominó la higiene deficiente. Se evidenció que a medida que la higiene bucal fue más deficiente, el grado de afección periodontal aumentó, por lo cual resulta importante aplicar medidas preventivo-curativas, para mejorar la salud periodontal y así disminuir los riesgos en este grupo de pacientes dispensarizados.The periodontal disease is related to the cardiovascular diseases, since the microorganisms of the gingival sulcus and of the periodontal pockets may aggravate the beginning and the course of these cardiovascular affections. A descriptive and cross-sectional study was conducted in a non-probabilistic sample of 210 cardiopathy patients of “Plaza de la Revolución ” Polyclinic in February 2003. They were applied the revised oral higiene index (R-OHI of Greene and Vermillion, and the revised periodontal index of Russell (R-PI.The following variables were studied: age, sex, periodontal state, and

  10. Adaptação cultural de instrumento para avaliação da capacidade física em cardiopatas Adaptación cultural de instrumento para evaluación de la capacidad física en cardiópatas Cultural adaptation of an instrument to assess physical fitness in cardiac patients

    Directory of Open Access Journals (Sweden)

    Gabriela de Barros Leite Domingues

    2011-04-01

    Full Text Available OBJETIVO: Validar o conteúdo e avaliar a confiabilidade do instrumento Veterans Specific Activity Questionnaire, adaptado culturalmente para uso na população brasileira de cardiopatas. MÉTODOS: O instrumento foi traduzido, retrotraduzido e analisado por comitê de juízes para avaliação das equivalências semântico-idiomática e cultural. As atividades físicas indicadas no instrumento incomuns ao cotidiano da população-alvo foram substituídas. Outro comitê de especialistas analisou a equivalência metabólica das atividades substituídas. A proporção de concordância de avaliação dos juízes foi quantificada pelo Índice de Validade de Conteúdo. O pré-teste foi realizado em duas etapas (n1 e n2 = 15. A confiabilidade foi avaliada por meio do teste re-teste (intervalo de 7-15 dias, n = 50. RESULTADOS: Na avaliação das equivalências semântico-idiomática e cultural, os itens com Índice de Validade de Conteúdo OBJETIVO: Validar el contenido y la confiabilidad del instrumento Veterans Specific Activity Questionnaire, adaptado culturalmente para uso en la población brasileña de cardiópatas. MÉTODOS: El instrumento fue traducido y retro traducido y analizado por comité de árbitros para evaluación de las equivalencias semántico-idiomática y cultural. Las actividades físicas indicadas en el instrumento, no comunes a lo cotidiano de la población de interés fueron sustituidas. Otro comité de especialistas analizó la equivalencia metabólica de las actividades sustituidas. La proporción de concordancia de evaluación de los árbitros fue cuantificada por el Índice de Validez de Contenido. La pre-test fue realizada en dos etapas (n1 y n2=15. La confiabilidad fue evaluada por medio de la prueba re-test (intervalo de 7-15 días, n=50. RESULTADOS: En la evaluación de las equivalencias semántico-idiomática y cultural, los itens con Índice de Validez de Contenido OBJECTIVE: To validate the content and to evaluate the

  11. Doença coronária obstrutiva em hepatopatas crônicos que aguardam transplante hepático Enfermedad coronaria obstructiva en hepatópatas crónicos que aguardan trasplante hepático Obstructive coronary disease in patients with chronic liver disease awaiting liver transplantation

    Directory of Open Access Journals (Sweden)

    Moacir Fernandes de Godoy

    2011-01-01

    grado importante con consecuente aumento de riesgo o incluso contraindicación para trasplante hepático. OBJETIVOS: Analizar la contribución de los factores de riesgo clásicos para la enfermedad arterial coronaria (EAC en pacientes portadores de IHA con y sin coronariopatía obstructiva. MÉTODOS: Evaluación de los factores de riesgo para EAC en 119 pacientes, en un servicio de referencia para trasplante hepático, con las siguientes características: más de 40 años de edad, portadores de IHA y sometidos a cinecoronariografía. RESULTADOS: Coronariopatía obstructiva fue detectada en 21 (17,6% de los casos. Estos pacientes presentaban realmente niveles bajos de colesterol, siendo de 129,0±53,5mg/dL con mediana de 117,0mg/dL en los hepatópatas con coronarias normales y 135,4±51,7mg/dL con mediana de 122,0mg/dL en los hepatópatas con coronariopatía obstructiva (P=0,8215. En la regresión logística multivariada, la edad, el sexo, el índice de masa corporal, así como las presencias de diabetes, de tabaquismo y de etilismo no tuvieron significancia estadística aislada en la diferenciación entre los grupos. También no hubo asociación con la etiología de la IHA. A su vez, la hipertensión arterial se mostró relevante en la asociación con EAC (P=0,0474. CONCLUSIÓN: Sólo la hipertensión arterial fue factor de riesgo con significancia estadística para el desarrollo de EAC en pacientes con IHA aguardando trasplante hepático. Por ser un factor de riesgo cambiable, este hallazgo orienta hacia una práctica de actitudes terapéuticas en la tentativa de evitarse o retardar el desarrollo de la EAC en estos pacientes.BACKGROUND: Advanced liver failure (ALF usually presents hypocholesterolemia. Nevertheless, some patients with ALF develops major coronary obstructive diseases with consequent increased risk or contraindication to liver transplantation. OBJECTIVE: To analyze the contribution of classical risk factors for coronary artery disease (CAD in patients

  12. Allelopathic activity of fresh and dry extracts of Stryphnodendron adstringens (Mart. Coville and Bauhinia forficata link leaves on the germination and initial development of tomato seedlings / Atividade alelopática dos extratos fresco e seco de folhas de barbatimão (Stryphnodendron adstringens (Mart. Coville e pata-devaca (Bauhinia forficata link sobre a germinação e desenvolvimento inicial de plântulas de tomate

    Directory of Open Access Journals (Sweden)

    Gisela Ferreira

    2009-07-01

    Full Text Available The objective of this study aimed at the verification of the allelopatic action of extracts of “pata-devaca” (Bauhinia forficata Link and “barbatimão” (Stryphnodendron adstringens (Mart. Coville on seeds of tomato (Lycopersicum esculentum Mill. Tomato seeds placed in translucent “gerbox” were treated with aqueous extracts prepared with fresh and dry leaves of the tested species at the following concentrations: 100%, 75%, 50%, 25%, and 0% (control. The experimental design was completely randomized with five treatments and five replications of 25 seeds per plot per species. The data were submitted to the analysis of variance and the means compared by Tukey test at 5% of probability. Germination percentage, mean time and germination rates (MGT and MGR, and mean of the primary root length were evaluated. No difference was found for germination percentage of tomato seeds for the different extracts. For MGR, all treatments with fresh leaf extract differed from the check. MGT and MGR showed differences among the following dry leaf extracts concentrations: 25%, 75% and 100%. All treatments presented inhibitory effect on the length of the primary root.O trabalho teve por objetivo verificar a ação alelopática de pata-de-vaca (Bauhinia forficata Link, e barbatimão (Stryphnodendron adstringens (Mart. Coville em sementes de tomate (Lycopersicum esculentum Mill. As sementes de tomate foram tratadas com extratos aquosos preparados a partir de folhas frescas e secas das espécies-teste nas concentrações de 100%, 75%, 50%, 25% e 0% (controle e acondicionadas em ‘gerbox’ transparente. O delineamento experimental foi inteiramente casualizado, com cinco tratamentos e cinco repetições de 25 sementes por parcela por espécie-teste. Foram avaliados porcentagem, tempo e velocidade médios de germinação e, comprimento médio de raiz primária. Os dados foram submetidos à análise de variância e as médias comparadas por Tukey a 5% de

  13. Do deposed adult male Sichuan snub-nosed monkeys Rhinopithecus roxellana roam as solitary bachelors or continue to interact with former band members?

    Institute of Scientific and Technical Information of China (English)

    Dapeng ZHAO; Baoguo LI

    2009-01-01

    @@ Dispersal pattems exhibited by group-living animals play an important role in individual reproductive success and survival, as well as population and social dynamics (Greenwood, 1980; Isbell and van Vuren, 1996; Kappeler and van Schaik, 2002). Dispersing individuals may emigrate voluntarily, or they may be forcibly evicted by other individuals (Pusey and Packer, 1987; Clobert et al., 2001). One cause of individual dispersal is when an extra-group male compels another male to leave a group of females. This phenomenon has been well documented in primates, especially Old World monkey species (e.g. Colobus vellerosus: Saj and Sicotte, 2005; Erythrocebus patas: Ohsawa, 2003; Macaca fascicularis: van Noordwijk and van Schaik, 2001).

  14. Mulher cardiopata com úlcera por pressão: reflexão fenomenológica sobre um modelo de cuidado clínico de conforto Mujer cardiópata con úlcera por presión: reflexión fenomenológica sobre un modelo de atención clínica de confort Female patient that suffers from heart disease with pressure ulcer: a phenomenological reflection on a clinical care model of comfort

    Directory of Open Access Journals (Sweden)

    Aurilene Lima da Silva

    2013-03-01

    Full Text Available Reflexão sobre a possibilidade de desenvolver um modo de cuidar, na prática clínica de enfermagem, de mulheres cardiopatas acometidas por úlcera por pressão durante a hospitalização, com vistas à promoção de conforto. Assim, objetivou-se desenvolver um modelo de cuidado baseado no método fenomenológico heideggeriano. Compreender este fenômeno motiva o desenvolvimento de ações que promovem o conforto de forma autêntica. Considera-se que o cuidado autêntico de enfermagem a esta clientela ressignifica a prática clínica de enfermagem e favorece a percepção de conforto.Reflexión sobre la posibilidad de desarrollar un modelo de cuidar, en la práctica clínica de enfermería, de mujeres cardiópatas acometidas por úlcera por presión durante el periodo de hospitalización, con el fin de promover la comodidad. Así, el objetivo fue desarrollar un modelo de atención basado en el método fenomenológico de Heidegger. Entender este fenómeno motiva acciones que promueven el confort auténtico. Se considera que el cuidado auténtico de enfermería dirigido a esta clientela resignifica la práctica clínica de enfermería y favorece la percepción de confort.This is a reflection on the possibility of developing, in nursing clinical practice, a care for cardiac women affected by pressure ulcer during hospitalization, in order to promote comfort. Thus, the objective was to develop a model of care based on Heidegger's phenomenological method. Once understanding this phenomenon motivates the development of actions that authentically promote comfort. It is considered that the genuine nursing care to this clientele seeks a new vision of clinical practice of nursing and favors the perception of comfort.

  15. Seroprevalence of Toxoplasma gondii infection in captive mammals in three zoos in Mexico City, Mexico.

    Science.gov (United States)

    Alvarado-Esquivel, Cosme; Gayosso-Dominguez, Edgar Arturo; Villena, Isabelle; Dubey, J P

    2013-09-01

    Antibodies to Toxoplasma gondii were determined in 167 mammals in three zoos in Mexico City, Mexico, using the modified agglutination test (MAT). Overall, antibodies to T. gondii were found in 89 (53.3%) of the 167 animals tested. Antibodies were found in 35 of 43 wild Felidae: 2 of 2 bobcats (Lynx rufus); 4 of 4 cougars (Puma concolor); 10 of 13 jaguars (Panthera onca); 5 of 5 leopards (Panthera pardus); 7 of 7 lions (Panthera leo); 2 of 3 tigers (Panthera tigris); 2 of 3 ocelots (Leopardus pardalis); 2 of 2 Sumatran tigers (Panthera tigris sumatrae); lof 2 Jaguarundi (Herpailurus jagouaroundi); but not in 0 of 2 oncillas (Leopardus tigrinus). Such high seroprevalence in wild felids is of public health significance because of the potential of oocyst shedding. Four of 6 New World primates (2 of 2 Geoffroy's spider monkeys [Ateles geoffroyi], 1 of 3 Patas monkeys [Erythrocebus patas], and 1 of 1 white-headed capuchin [Cebus capucinus]) had high MAT titers of 3,200, suggesting recently acquired infection; these animals are highly susceptible to clinical toxoplasmosis. However, none of these animals were ill. Seropositivity to T. gondii was found for the first time in a number of species.

  16. 0~1岁儿童急性肺炎病原学研究及用药合理性分析%Etiological research and medication rationality analysis of acute pneumonia in 0~1 years old

    Institute of Scientific and Technical Information of China (English)

    王晓晖; 张楠; 黄芳

    2013-01-01

    目的 分析住院的0~1岁急性肺炎儿童呼吸道病原学结果、临床特征,评价抗菌药物使用的合理性.方法 2010年12月至2012年11月我院收治34例肺炎患儿,咽拭子送北京市疾病预防控制中心进行流感病毒核酸等快速检测,痰液送院内细菌室进行细菌培养.儿童药物利用指数(children drug utilization index,cDUI)评价抗菌药物用药剂量合理性,cDUI接近1.0时用药剂量合理.药物的用药频度(defined daily dose statistic,DDDs)数值大即临床对此药选择倾向性大.结果 34例急性肺炎患儿中,病毒感染21例,细菌感染9例,混合感染4例.存在基础疾病发生细菌性肺炎(4/9)的机会高于病毒感染(5/21)(P<0.001),有呼吸道感染患者接触史患儿病毒检出率(12/21)高于细菌检出率(4/9)(P=0.01),无交叉感染危险时,婴儿更易出现细菌感染(P=0.006).25例病毒检测阳性患儿痰培养见条件致病菌定植13例,致病菌4例.细菌感染时抗菌药物联用比例(4/9)高于混合感染(1/4)(P =0.001),各组抗菌药物使用天数差异无统计学意义(P=0.29).本研究共涉及7种抗菌药物,头孢曲松(DDDs=1813.45、总用药187 d)和头孢呋新(DDDs=1513.73、总用药162 d)用药频度、总用药天数高于其余5种抗菌药物.所有剂型抗菌药物cDUI均≤1.0,由高到低分别是:阿莫西林克拉维酸钾(cDUI=1.0)、头孢呋辛(cDUI =0.89)、头孢曲松(cDUI=0.87)、阿奇霉素口服剂和头孢吡肟(cDUI=0.80)、麦迪霉素口服剂(cDUI=0.75)、青霉素注射剂(cDUI=0.50).结论 病毒是本次婴儿急性肺炎的主要病原,病毒为细菌定植提供条件,头孢曲松的过多使用加剧条件致病菌致病风险.部分患儿抗菌药物疗程长或联合使用属于不合理用药.%Objective To analyze the etiological results and clinical characteristics in infants with acute pneumonia at the age of 0 ~ 1 years and to evaluate the rationality of the use of antibiotics.Methods Thirty-four infants hospitalized during Dec 2010 to Nov 2012 were selected.The throat swabs were sent to the Beijing Disease Prevention and Control Center for rapid nucleic acid test for influenza; the sputum was sent to the bacteriological laboratory of the hospital for the bacterial culture.Children drug utilization index (cDUI)was used to assess the rationality of the medication amount of antibiotic drugs.For defined daily dose statistic (DDDs),the larger the value of DDDs,the more frequent the clinical use of the drug.Results In the confirmed cases of acute pneumonia,21 cases were of viral infection,9cases were of bacterial infection and 4 cases were of mixed infection.The probability of bacterial pneumonia (4/9) was higher than that of viral pneumonia(5/21) in the case with underlying disease (P <0.001) ;the virus detection rate(12/21) of children with contact history with respiratory tract infection patients was higher than bacteria detection rate(4/9)(P =0.01).In case of no risk of cross infection,the infants were more susceptible to bacterial infection (P =0.006).The sputum culture of 25 cases of positive virus detection showed 13 cases of colonization of conditional pathogenic bacteria and 4 cases of pathogenic bacteria.The ratio of combination use of antibiotic drugs in case of bacterial infection (4/9) was higher than that in mixed infection (1/4) (P =0.001).The durations of the use of antibiotic drugs for every group showed no statistical difference (P =0.29).This research involved 7 antibiotic drugs.The medication frequencies and durations of ceftriaxone (DDDs =1813.45,total medication duration =187 days) and cefuroxirne (DDDs =1513.73,total medication duration =162 days) were higher than those of the other 5 antibiotic drugs.The cDUI of all drugs ≤ 1.0.The decreasing order of drugs by cDUI was amoxicillin and clavulanate potassium (cDUI =1.0),cefuroxime (cDUI=0.89),ceftriaxone (cDUI =0.87),azithromycin oral agent and cefepime (cDUI =0.80),midecamycin oral agent (cDUI =0.75) and penicillin injections (cDUI =0.50).Conclusion Virus is the main pathogen of the acute pneumonia in children in this research.Virus provides preliminary conditions for bacterial colonization.The overuse of ceftriaxone aggravates the pathogenic risks of conditional pathogenic virus.Some children are treated by antibiotic drugs for a long time or by the combination use of drugs,which are irrational mediation.

  17. A mobile element-based evolutionary history of guenons (tribe Cercopithecini

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    Tosi Anthony J

    2007-01-01

    Full Text Available Abstract Background Guenons (tribe Cercopithecini are a species-rich group of primates that have attracted considerable attention from both primatologists and evolutionary biologists. The complex speciation pattern has made the elucidation of their relationships a challenging task, and many questions remain unanswered. SINEs are a class of non-autonomous mobile elements and are essentially homoplasy-free characters with known ancestral states, making them useful genetic markers for phylogenetic studies. Results We identified 151 novel Alu insertion loci from 11 species of tribe Cercopithecini, and used these insertions and 17 previously reported loci to infer a phylogenetic tree of the tribe Cercopithecini. Our results robustly supported the following relationships: (i Allenopithecus is the basal lineage within the tribe; (ii Cercopithecus lhoesti (L'Hoest's monkey forms a clade with Chlorocebus aethiops (African green monkey and Erythrocebus patas (patas monkey, supporting a single arboreal to terrestrial transition within the tribe; (iii all of the Cercopithecus except C. lhoesti form a monophyletic group; and (iv contrary to the common belief that Miopithecus is one of the most basal lineages in the tribe, M. talapoin (talapoin forms a clade with arboreal members of Cercopithecus, and the terrestrial group (C. lhoesti, Chlorocebus aethiops and E. patas diverged from this clade after the divergence of Allenopithecus. Some incongruent loci were found among the relationships within the arboreal Cercopithecus group. Several factors, including incomplete lineage sorting, concurrent polymorphism and hybridization between species may have contributed to the incongruence. Conclusion This study presents one of the most robust phylogenetic hypotheses for the tribe Cercopithecini and demonstrates the advantages of SINE insertions for phylogenetic studies.

  18. Sobredentadura metálica en paciente bruxópata

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    Carmen de los Milagros García Alguacil

    2014-11-01

    Full Text Available Se presenta el caso de un paciente masculino de 49 años de edad que acudió a la consulta de prótesis, el mismo había recibido tratamiento de estomatología general integral, donde se le sugirió la exodoncia de los dientes anteroinferiores, por la pérdida de la mitad de sus coronas anatómicas. Se le realizaron exámenes radiográficos y test de vitalidad, comprobando la vitalidad de los dientes; se le diagnosticó una disfunción masticatoria producto del hábito del bruxismo y se procedió a realizar una prótesis parcial removible metálica inferior (sobredentadura, la cual permitió controlar el hábito parafuncional y lograr la rehabilitación en un mismo tratamiento. Además, se logró devolver la funcionabilidad y la integridad de los dientes remanentes (sin necesidad de realizar tratamientos pulporradiculares, restaurando la dimensión vertical oclusiva y el contorno facial. Se propuso este tratamiento combinado, como alternativa eficaz en el manejo del bruxismo en pacientes parcialmente desdentados

  19. Plastia sustitutiva del LCA con tendones de la pata de ganso cuadruples

    OpenAIRE

    1999-01-01

    Se han estudiado retrospectivamente 44 casos de pacientes a los que se les realizó por vía artrocóspica una plastia sustitutiva intraticular de reconstrucción del LCA, con tendones de Semitendinoso y Recto Interno antólogos, en 4 fascículos. La edad media de los pacientes fue de 25 años. Los resultados a corto plazo (2 años) obtenidos con KT-1000 a 30 Ib han sido excelente-bueno en 40 casos y aceptable en 4 casos. Cuatro casos referían sensación de inestabilidad. Los test de Lachman y Pívot-S...

  20. Rehabilitación ocluso-articular en un paciente bruxópata

    Directory of Open Access Journals (Sweden)

    José Miguel Montero Parrilla

    2011-09-01

    Full Text Available Se realizó la presentación del caso de un paciente masculino de 68 años de edad que acudió a la Consulta de Trastornos Temporomandibulares de la Facultad de Estomatología de La Habana, por presentar problemas estéticos y dificultades masticatorias. Durante la anamnesis y el examen físico se observaron facetas de desgastes oclusales, disminución de la dimensión vertical y prominencias óseas asociadas al bruxismo. Se realizó la discusión del caso y el tratamiento seguido para su rehabilitación ocluso-articular. El resultado final fue la restauración de la estética y la función.

  1. Marchenko-Pastur Theorem and Bercovici-Pata bijections for heavy-tailed or localized vectors

    CERN Document Server

    Benaych-Georges, Florent

    2012-01-01

    The celebrated Marchenko-Pastur theorem gives the asymptotic spectral distribution of sums of random, independent, rank-one projections. Its main hypothesis is that these projections are more or less uniformly distributed on the first grassmannian, which implies for example that the corresponding vectors are delocalized, i.e. are essentially supported by the whole canonical basis. In this paper, we propose a way to drop this delocalization assumption and we generalize this theorem to a quite general framework, including random projections whose corresponding vectors are localized, i.e. with some components much larger than the other ones. The first of our two main examples is given by heavy tailed random vectors (as in a model introduced by Ben Arous and Guionnet or as in a model introduced by Zakharevich where the moments grow very fast as the dimension grows). Our second main example is given by vectors which are distributed as the Brownian motion on the unit sphere, with localized initial law. Our framewor...

  2. La crisis del relato y la apoteosis del sicópata

    OpenAIRE

    Goyes Narváez, Julio César

    2014-01-01

    Jesús González Requena es catedrático de Comunicación Audiovisual,coordinador del doctorado en Teoría, Análisis y DocumentaciónCinematográfica de la Universidad Complutense de Madridy presidente de la Asociación Cultural Trama y Fondo. Estuvo en laUniversidad Nacional de Colombia como conferencista en la III Feriade la Comunicación. Es autor de La metáfora del espejo. El cine deDouglas Sirk (Hiperión, 1986), El discurso televisivo: espectáculode la posmodernidad (Cátedra, 1988), El espectácul...

  3. La crisis del relato y la apoteosis del sicópata

    OpenAIRE

    2014-01-01

    Jesús González Requena es catedrático de Comunicación Audiovisual,coordinador del doctorado en Teoría, Análisis y DocumentaciónCinematográfica de la Universidad Complutense de Madridy presidente de la Asociación Cultural Trama y Fondo. Estuvo en laUniversidad Nacional de Colombia como conferencista en la III Feriade la Comunicación. Es autor de La metáfora del espejo. El cine deDouglas Sirk (Hiperión, 1986), El discurso televisivo: espectáculode la posmodernidad (Cátedra, 1988), El espectácul...

  4. Isolation and characterization of faecal bifidobacteria and lactobacilli isolated from dogs and primates.

    Science.gov (United States)

    Strompfová, Viola; Lauková, Andrea

    2014-10-01

    Although bifidobacteria and lactobacilli have been suggested beneficial for the host and are components of many probiotics and competitive exclusion mixtures, the knowledge on abundance, metabolic and probiotic characteristics in isolates from dogs and monkeys is still limited. The present study was aimed to isolate Bifidobacterium and Lactobacillus strains (faeces of 22 dogs and of 5 primates: Cebus apella, Eulemur fulvus, Erythrocebus patas, Macaca fascicularis, Papio hamadryas) with the MALDI-TOF identification system Lactobacillus murinus, Bifidobacterium animalis and Pediococcus acidilactici were more frequently isolated species in dogs while Lactobacillus plantarum was isolated in several species of primates. Ten strains of 6 species were assayed for enzymatic activities (only Lactobacillus reuteri strains showed no undesirable enzymatic activity), antimicrobial susceptibility (detected higher minimum inhibitory concentration levels for tetracycline and gentamicin), and inhibitory activity against 15 indicator bacteria. All strains inhibited Gram-negative indicators while lactobacilli showed larger inhibition zones than bifidobacteria. L. reuteri II/3b/a (isolate from M. fascicularis) showed the best antimicrobial properties. Resistance to bile (0.3% w/v) was observed in all tested strains (no decrease of CFU/ml) whereas the decrease of 68.4-94.4% (after 90 min exposition) and 78.4-99.9% CFU/ml (after 180 min) depending on the strain was detected in the artificial gastric juice.

  5. Revisiting play elements and self-handicapping in play: a comparative ethogram of five Old World monkey species.

    Science.gov (United States)

    Petrů, Milada; Spinka, Marek; Charvátová, Veronika; Lhota, Stanislav

    2009-08-01

    Play behavior has been viewed as a mixture of elements drawn from "serious" behavior, interspersed by ritualized play signals. Two other types of play behaviors have been overlooked: patterns that are dissimilar from any serious behavior and patterns with self-handicapping character, that is, those that put the animal into unnecessary disadvantageous positions or situations. Here the authors show that these 2 types of patterns can constitute a major part of play repertoire. From our own videorecordings and observations, we constructed play ethograms of 5 monkey species (Semnopithecus entellus, Erythrocebus patas, Chlorocebus pygerythrus, Cercopithecus neglectus, and Cercopithecus diana). The authors evaluated the self-handicapping character of each pattern and in Hanuman langurs also the (dis)similarity to serious behavior. Of the 74 patterns in the 5 species, 33 (45%) were judged to have a self-handicapping character. Of 48 patterns observed in langurs, 16 (33%) were totally dissimilar to any serious langur behavior known to us. The authors discuss the possibility that the different types of play elements may have different functions in play.

  6. The effect of early communication with infants on language development of children aged 1 year old in the city%婴儿早期沟通对城市1岁小儿语言发展的影响

    Institute of Scientific and Technical Information of China (English)

    郝波; Fletcher P; 赵更力; 周敏; 张文坤; 张小松; 陈丽君; 梁卫兰; 张致祥; Tardif T

    2008-01-01

    目的:了解小儿语言发育水平及早期沟通对小儿语言发展的影响.方法:采用定量研究方法,对在同一家医院出生的800对正常足月儿及其母亲,分别于42天、6个月及12个月时用家庭背景问卷,于12个月时用"中文早期语言与沟通发展量表简表"(CCDI)及家庭背景问卷对母亲进行面对面问卷调查.用均数、中位数和率描述语言发展水平,用两独立样本秩和检验分析婴儿早期沟通对小儿语言发展的影响.结果:12个月时,71.6%小儿至少会用1个手势,69.0%会理解或表达至少1个词.1岁时小儿手势得分中位数为6.0(0~10),词汇得分中位数为85.0(0~194).父母在42天内、1~6个月内经常与孩子进行语言交流、给孩子做皮肤按摩、亲自养育孩子,则小儿语言得分较高.结论:婴儿早期沟通利于1岁时小儿语言发展.

  7. The needing investigation and analysis of health care outpatient service towards 484 0~1 years old children's parents%0~1岁儿童家长对保健门诊护理服务需求调查484例分析

    Institute of Scientific and Technical Information of China (English)

    覃文菊; 雷泽东

    2010-01-01

    目的:了解0~1岁儿童家长对儿童保健的认知和对保健门诊护理服务的需求.方法:选取儿保门诊就诊的484例婴儿家长进行问卷调查,采用SPSS 11.0软件统计分析结果.结果:①一般情况:高中或中专以下学历的母亲占54%,月收入>2 000元的家庭占75%,剖宫产率41%,母乳喂养率84%;②保健情况:96%以上儿童进行新生儿疾病筛查、预防接种和定期体格检查,60%以上家长坚持给婴儿做被主动体操和婴儿抚触,参加早教活动和科学育儿知识讲座的家长低于50%,大部分母亲对婴儿发育规律、母乳喂养和亲子依恋等知识了解欠缺;③对保健服务的需求:常见病的预防仍是首要,其次是儿童营养和喂养、智能促进,低文化层次母亲对儿童心理发育不够重视.结论:对婴儿家长积极开展健康教育讲座和讲授早教知识,传授给家长更多的科学育儿知识;加强低文化层次母亲对儿童心理知识的了解,以促进儿童心理健康发展;提高纯母乳喂养率,提高新生儿疾病筛查率,改善儿童保保健服务质量.

  8. EFFECTS OF P APPLICATION ON N AND P ABSORPTION AND SUGAR ACCUMULATION BY 1-YEAR-OLD ALOE VERA IRRIGATED WITH SEAWATER%施磷对海水灌溉下一年生芦荟氮磷吸收及糖分积累的影响

    Institute of Scientific and Technical Information of China (English)

    邵晶; 刘玲; 刘兆普; 宁建凤; 郑青松

    2008-01-01

    在对大田海水灌溉试验的基础上,进行海水灌溉下的肥料试验。库拉索芦荟(Aloe vera)是一种CAM光合碳同化途径的多年生旱生经济植物,具有一定的耐盐性。在国外,芦荟研究的成果被广泛应用在医药、保健、食品等行业,已形成一大产业。最近的研究报告表明,与其他植物一样,盐分胁迫造成芦荟体内盐分积累、营养元素缺失,

  9. ¡Cuídese, no meta la pata!: sexualidad juvenil en escolares de Medellín (Colombia

    Directory of Open Access Journals (Sweden)

    Doris Elena Ospina Muñoz

    2013-12-01

    Full Text Available Objetivo: Discutir con escolares, mediante taller educativo, resultados de investigaciones sobre sexualidad juvenil e identificar ejes para la educación sexual y la formación de docentes. Metodología: Estudio cualitativo sobre sexualidad con escolares de grado 10º en Medellín, Colombia (2008-2011. Previo consentimiento se realizaron actividades educativas sobre imagen corporal, disonancia cognitiva, maternidad y paternidad adolescente, derechos de la comunidad LGBTI y ética sexual. Se analizaron evidencias escritas bajo la modalidad de discusión de expertos. Hallazgos: Los jóvenes reconocieron la sexualidad como asunto central que requiere apropiación del cuerpo, reflexividad y comunicación efectiva con padres y maestros; sin embargo, prevalece en ellos la visión trágica de la vivencia sexual. Conclusión: Los adolescentes requieren educación para la libertad, donde participen de espacios propuestos para ellos o creados por ellos, según sus necesidades y contextos y puedan tomar decisiones autónomas y responsables.

  10. The WHO Collaborating Centre for Research and Control of Schistosomiasis at Niamey, Niger

    Directory of Open Access Journals (Sweden)

    Chippaux J-P

    1997-01-01

    Full Text Available The Centre de Recherche sur les Méningites et les Schistosomes (CERMES is a research institute depending on the Organisation de Coordination et de Coopération pour la lutte contre les Grandes Endémies - a West African Organization for Public Health - devoted to the studies on schistosomiasis and meningitis. The staff includes 32 persons with 11 scientists and one financial officer. The activities of the CERMES involving schistosomiasis concern three research units: (a ecology of human and animal schistosomiasis transmission; the CERMES defined the different patterns of schistosomiasis transmission in Niger (involving African dry savana; in this field, we have shown, (i the existence of important variability in conditions of transmission of S. haematobium and, (ii natural hybridization between parasitic species of the ruminants (S. bovis and S. curassoni and genetic interaction between human and animal parasites; (b definition of morbidity indicators usable for rapid assessment methods, for appraisal of the severity of the disease and for the evaluation of the efficiency of control methods; we have established the correlation between ultrasonographic data and some cheap and simple field indicators; (c immune response and protective immunity induced by recombinant glutathion S-transferase (Sm28, Sb28 and Sh28 in homologous and heterologous animal models including goats, sheep and non human primates (Erythrocebus patas. In Niger, we participate in all control programs against schistosomiasis to define control strategies, to supervise operations and to participate in their evaluation with external experts. International collaborations constitute a frame including four laboratories in Africa and six laboratories in developed countries (Europe and USA

  11. Efectos de el niño en el desarrollo, el fenotipo adulto y la reproducción del bobo de patas azules /

    OpenAIRE

    Ancona Martínez, Sergio Iván

    2012-01-01

     tesis que para obtener el grado de Doctorado en Ciencias Biomédicas, presenta Sergio Iván Ancona Martínez ; asesor Hugh Michael Drummond Durey98 páginas : ilustracionesDoctorado en Ciencias Biomédicas UNAM, Instituto de Ecología, 2012

  12. Pedagoogiline mustrikeel ja järgmise põlvkonna e-õppe lahendused / Kai Pata, Terje Väljataga, Mart Laanpere

    Index Scriptorium Estoniae

    Pata, Kai

    2006-01-01

    Analüüsitakse e-õpikeskkondade põlvkonnavahetuse tagamaid ja suundi Euroopa Liidu 6. raamprogrammi rahvusvahelise uurimisprojekti iCamp tegemiste kontekstis. Projekti eesmärk on luua infotehnoloogiline infrastruktuur, mis toetaks e-õpet Euroopa ühtses kõrgharidusruumis, integreerides erinevaid e-õppe alaseid lahendusi

  13. Reflexiones sobre psicoprofilaxis quirúrgica en niños cardiópatas (II) Cuestionamiento de la psicoprofilaxis como simple información.

    OpenAIRE

    M Arrazola Aranzadi; JA Vicente Sánchez

    1989-01-01

    Describe las ansiedades de una niña de cinco años, a la hora de enfrentarse a la operación de corazón a la que iba a ser sometida y las dificultades para asumir la información acerca de lo que le iba a suceder. Se comentan los mecanismos de defensa que más utiliza, y su evolución psicológica hasta dos años después de la operación. Los autores son partidarios de una metodología individualizada, adaptada al funcionamiento mental del niño, en la práctica de la psicoprofilaxis quirúrgica....

  14. Rehabilitación ocluso-articular en un paciente bruxópata Occlusal-articular rehabilitation in a patient with bruxism

    Directory of Open Access Journals (Sweden)

    José Miguel Montero Parrilla

    2011-09-01

    Full Text Available Se realizó la presentación del caso de un paciente masculino de 68 años de edad que acudió a la Consulta de Trastornos Temporomandibulares de la Facultad de Estomatología de La Habana, por presentar problemas estéticos y dificultades masticatorias. Durante la anamnesis y el examen físico se observaron facetas de desgastes oclusales, disminución de la dimensión vertical y prominencias óseas asociadas al bruxismo. Se realizó la discusión del caso y el tratamiento seguido para su rehabilitación ocluso-articular. El resultado final fue la restauración de la estética y la función.This is the presentation of the case of a male patient aged 68 came to our consultation of temporomandibular disorders of the Stomatology Faculty of Ciudad de La Habana due to esthetic problems and mastication difficulty. During anamnesis and physical examination it was possible to note occlusal wear facets, decrease of vertical dimension and bone prominences associated with bruxism. Case was discussed and treatment was followed for its occlusal-articular rehabilitation. Final result was the restoration of esthetics and function.

  15. Reflexiones sobre psicoprofilaxis quirúrgica en niños cardiópatas (II Cuestionamiento de la psicoprofilaxis como simple información.

    Directory of Open Access Journals (Sweden)

    M Arrazola Aranzadi

    1989-01-01

    Full Text Available Describe las ansiedades de una niña de cinco años, a la hora de enfrentarse a la operación de corazón a la que iba a ser sometida y las dificultades para asumir la información acerca de lo que le iba a suceder. Se comentan los mecanismos de defensa que más utiliza, y su evolución psicológica hasta dos años después de la operación. Los autores son partidarios de una metodología individualizada, adaptada al funcionamiento mental del niño, en la práctica de la psicoprofilaxis quirúrgica.

  16. Las patas en la fuente y la comunidad organizada: dislocación comunitaria e identidad en los orígenes del peronismo

    Directory of Open Access Journals (Sweden)

    Pablo Pizzorno

    2013-06-01

    Full Text Available El presente trabajo se concentra en el proceso de constitución identitaria del peronismo, retomando el lugar que ocupa la identidad en determinados estudios canónicos sobre los orígenes del peronismo y en clave de respuesta a los límites de las explicaciones basadas en el racionalismo instrumental. A partir de allí, se indaga en la conformación de un nuevo sujeto popular, articulado a partir de la interpelación peronista e identificado en la representación con Perón, cuya emergencia agrietó decisivamente el orden tradicional. Dicho proceso se plasmó en la llamada “crisis de la deferencia”, entendida como el fin de la aceptación de un lugar establecido en un orden hegemónico, expresando así un quiebre de los lugares asignados previamente en la comunidad política. Esta dislocación comunitaria de origen marcó constitutivamente al régimen peronista –donde convivieron tensamente tendencias orientadas al orden y a la ruptura– atentando contra los intentos de sutura estatal de aquella ruptura inicial. Esta última reflexión es guiada por el aporte de una serie de teorizaciones sobre el populismo como matriz específica en el marco de las Identidades políticas.

  17. Ocular oxyspirurosis of primates in zoos: intermediate host, worm morphology, and probable origin of the infection in the Moscow zoo.

    Science.gov (United States)

    Ivanova, E; Spiridonov, S; Bain, O

    2007-12-01

    Over the last century, only two cases of ocular oxyspirurosis were recorded in primates, both in zoos, and two species were described: in Berlin, Germany, Oxyspirura (O.) conjunctivalis from the lemurid Microcebus murinus, later also found in the lorisid Loris gracilis; in Jacksonville, Florida, O. (O.) youngi from the cercopithecid monkey Erythrocebus patas. In the present case from the Moscow zoo, oxyspirurosis was recorded in several species of Old World lemuriforms and lorisiforms, and some South American monkeys. i) The intermediate host was discovered to be a cockroach, as for O. (O.) mansoni, a parasite of poultry. The complete sequence identity between ITS-1 rDNA from adult nematodes of the primate and that of the larval worms from the vector, Nauphoete cinerea, confirmed their conspecificity. ii) Parasites from Moscow zoo recovered from Nycticebus c. coucang were compared morphologically to those from other zoos. The length and shape of the gubernaculum, used previously as a distinct character, were found to be variable. However, the vulvar bosses arrangement, the distal extremity of left spicule and the position of papillae of the first postcloacal pair showed that the worms in the different samples were not exactly identical and that each set seemed characteristic of a particular zoo. iii) The presence of longitudinal cuticular crests in the infective stage as well as in adult worms was recorded. Together with several other morphological and biological characters (long tail and oesophagus, cockroach vector), this confirmed that Oxyspirura is not closely related to Thelazia, another ocular parasite genus. iv) The disease in the Moscow zoo is thought to have started with Nycticebus pygmaeus imported fromVietnam, thus the suggestion was that Asiatic lorisids were at the origin of the Moscow set of cases. The natural host(s) for the Berlin and Jacksonville cases remain unknown but they are unlikely to be the species found infected in zoos. Consequently the

  18. Ocular oxyspirurosis of primates in zoos: intermediate host, worm morphology, and probable origin of the infection in the Moscow zoo

    Directory of Open Access Journals (Sweden)

    Ivanova E.

    2007-12-01

    Full Text Available Over the last century, only two cases of ocular oxyspirurosis were recorded in primates, both in zoos, and two species were described: in Berlin, Germany, Oxyspirura (O. conjunctivalis from the lemurid Microcebus murinus, later also found in the lorisid Loris gracilis; in Jacksonville, Florida, O. (O. youngi from the cercopithecid monkey Erythrocebus patas. In the present case from the Moscow zoo, oxyspirurosis was recorded in several species of Old World lemuriforms and lorisiforms, and some South American monkeys. i The intermediate host was discovered to be a cockroach, as for O. (O. mansoni, a parasite of poultry. The complete sequence identity between ITS-1 rDNA from adult nematodes of the primate and that of the larval worms from the vector, Nauphoete cinerea, confirmed their conspecificity. ii Parasites from Moscow zoo recovered from Nycticebus c. coucang were compared morphologically to those from other zoos. The length and shape of the gubernaculum, used previously as a distinct character, were found to be variable. However, the vulvar bosses arrangement, the distal extremity of left spicule and the position of papillae of the first postcloacal pair showed that the worms in the different samples were not exactly identical and that each set seemed characteristic of a particular zoo. iii The presence of longitudinal cuticular crests in the infective stage as well as in adult worms was recorded. Together with several other morphological and biological characters (long tail and oesophagus, cockroach vector, this confirmed that Oxyspirura is not closely related to Thelazia, another ocular parasite genus. iv The disease in the Moscow zoo is thought to have started with Nycticebus pygmaeus imported fromVietnam, thus the suggestion was that Asiatic lorisids were at the origin of the Moscow set of cases. The natural host(s for the Berlin and Jacksonville cases remain unknown but they are unlikely to be the species found infected in zoos

  19. Phototherapy with low intensity laser in carrageenan-induced acute inflammatory process in mice paw - dosimetry studies; Fototerapia com laser em baixa intensidade em processo inflamatorio agudo induzido por carragenina em pata de camundongos - estudos de dosimetria

    Energy Technology Data Exchange (ETDEWEB)

    Meneguzzo, Daiane Thais

    2010-07-01

    The importance of modulation of inflammation on the treatment of inflammatory diseases and the difficulty in determining the laser irradiation parameters has led us to study the effects of different protocols of phototherapy with low intensity laser (power, energy, time and place of irradiation) in the treatment and prevention of edema in acute inflammatory process using the experimental model of paw edema induced by carrageenan (CGN) in three strains of mice (Balb-c, Swiss and C57BL/6). The first stage of the study evaluated different combinations of energy (1J and 3J) with different powers (30, 60 and 100mW) in Balb-C mice paw irradiated 1 and 2h after injection of CGN. The second stage studied different combinations of location (foot, inguinal lymph nodes and both) and exposure time (2 and 1h before, 1h and immediately before the CGN, 1 and 2h and 3.5 and 4.5h after CGN) using fixed irradiation parameters (1J, 100mW, 35J/cm{sup 2}, spot area of 0.028 cm{sup 2}). The third stage compared different strains of mice Balb-c and C57BL/6) in the best local and time parameters found in step 2. At all stages, we evaluated the change in paw volume by plethysmography and inflammatory infiltrate by histomorphometry or analysis of myeloperoxidase (MPO). The results showed that laser phototherapy treated and prevented edema and modulated the inflammatory process with paw and inguinal lymph nodes irradiations accordingly with the parameters and mice strain used. (author)

  20. Pata es la traviesa : La cortesana Estefanía, el engaño mutuo y la sífilis en El casamiento engañoso

    OpenAIRE

    Adrián J. Sáez

    2012-01-01

    This article analizes the figure of doña Estefanía de Caicedo, woman who Campuzano gets married, justifying her immoral behaviour for her attitude and tricks («tapada», cosmet-ics, etc.). Furthermore, it is also studied her relation with syphilis, illness she passes on to the second lieutenant inside the scheme of mutual deceive presented in this cervantine novel. Se analiza la figura de doña Estefanía de Caicedo, mujer con la que se casa Campuzano, justificando su condición licenciosa por...

  1. Perfil clínico de personalidad mediante el Inventario Clínico Multiaxial (MCMI-II) en población ludópata del Instituto Nacional de Salud Mental Honorio Delgado – Hideyo Noguchi

    OpenAIRE

    Paredes Torres, Melissa Noemí; Sandoval Guerrero, Yanina

    2015-01-01

    Objetivo: Determinar y describir el perfil clínico de la personalidad promedio, determinar el porcentaje de sujetos que presentan trastornos de personalidad, determinar la existencia de patrones clínicos y patologías severas de la personalidad e identificar la media de trastornos de la personalidad por sujeto. Metodología: El tipo de estudio fue cuantitativo y de nivel descriptivo. El diseño de la investigación fue no experimental, transversal y retrospectivo, realizado a 19 pacientes con dia...

  2. La reducción del número de animales de experimentación y el cálculo del tamaño muestral: una mesa con cinco patas.

    OpenAIRE

    F Villamayor

    2014-01-01

    El cálculo del tamaño muestral necesario para la consecución de los objetivos de un experimento está basado en cuatro factores interdependientes: tamaño de efecto, nivel de significación, potencia estadística, y variabilidad de la muestra. El trabajo de planificación previo a la ejecución del estudio es fundamental para obtener el máximo de información con el número mínimo de animales.

  3. La reducción del número de animales de experimentación y el cálculo del tamaño muestral: una mesa con cinco patas.

    Directory of Open Access Journals (Sweden)

    F Villamayor

    2014-01-01

    Full Text Available El cálculo del tamaño muestral necesario para la consecución de los objetivos de un experimento está basado en cuatro factores interdependientes: tamaño de efecto, nivel de significación, potencia estadística, y variabilidad de la muestra. El trabajo de planificación previo a la ejecución del estudio es fundamental para obtener el máximo de información con el número mínimo de animales.

  4. Anti-inflammatory activity of Momordica charantia in edema paw and in cortisol seric modulation; Potencial antiinflamatorio da Momordica charantia no edema de pata e na modulacao do cortisol serico

    Energy Technology Data Exchange (ETDEWEB)

    Magnata, Simey S.L.P. [Pernambuco Univ., Recife, PE (Brazil). Dept. de Energia Nuclear]. E-mail: sfmagnata@terra.com.br; Correia, Marilia B.L.; Brandao, Jose Odinilson C.; Souza, Grace M.L.; Catanho, Maria Teresa J.A. [Pernambuco Univ., Recife, PE (Brazil). Dept. de Biofisica e Radiobiologia; Terra, Daniele A.; Amorim, Lucia F. [Rio Grande do Norte Univ., Natal, RN (Brazil). Dept. de Fisiologia

    2005-07-01

    The first sources that the humanity disposed to disease's treatment was plants and herbs. The Momordica charantia, Melao de Sao Caetano (bitter melon), occur in South and Central America and in East, it has been used as an anti-diabetic agent, anti-tumor, anti-helmintic and anti-ulcerogenic. The objective of this study is to research the Momordica charantia's activity on inflammatory process and the change on cortisol hormone seric concentration. To evaluate the anti-inflammatory activity were used mice (n=5) in test groups (30,60,100,250 mg/kg of extract) and control (negative and positive) groups (AAS 250 mg/kg and NaCl 0,9%); the inflammatory agent (carrageenan 1% p/v, 0,1 mL) was injected into right hind paw planter surface, 30 min after, the groups received each dose IP of extract, AAS and solution saline respectively; 4 hour after the mice was sacrificed and the difference between right and left hind foot mass was measured. There was a significant reduction (p<0,05)in carrageenan-induced edema paw at test from control group, the best result was obtained at 60 mg/kg dose which inhibits edema formation by 50%. To determinate the cortisol concentrations male Wistar rats, were divided in three groups: control, test A (2 hours of treatment) and test B (4 hours of treatment). The control group received 0,25 mL of saline solution (NaCl) 0,9% and the test groups 0,25 mL of Momordica charantia's aqueous extract, obtained by decoction of green leaves, (31,16 mg/kg animal); all by via IP. After the treatment, the animals were sacrificed and the serum obtained for realization of dosages. The cortisol was determined through radioimmunoassay. The results showed a reduction on a average by 83,9% from control group. The Momordica charantia's extract showed a high anti-inflammatory effect and was capable of reducing the seric cortisol on normal rats. (author)

  5. Alterações morfométricas em músculo respiratório de ratos submetidos à imobilização de pata Morphometric alterations in respiratory muscle of rats submitted to paw immobilization

    Directory of Open Access Journals (Sweden)

    Francisco Fleury Uchôa Santos-Júnior

    2010-06-01

    Full Text Available A imobilização é um recurso frequentemente utilizado na prática clínica, sendo comum em patologias álgicas e nas fraturas. O objetivo deste estudo foi analisar a influência do processo de imobilização em músculo do sistema respiratório, o diafragma. O experimento foi efetuado com 12 ratos Wistar machos divididos em dois grupos, controle e imobilizado. O procedimento de imobilização foi realizado através de um método alternativo de imobilização por fita adesiva, sendo mantida por duas semanas. Analisou-se a morfometria das fibras do diafragma com coloração de hematoxilina e eosina. Ao compararmos o diâmetro médio das fibras musculares do diafragma dos animais imobilizados (47,15μm ± 0,329μm em relação ao controle (54,67μm ± 0,396μm, encontramos diferença estatística entre os grupos (p Immobilization is a frequently used procedure in clinical practice and common in pain diseases and fractures. This study examined the influence of immobilization in a muscle-related respiratory system, the diaphragm. This experiment was conducted with twelve male rats divided into two groups, control and immobilized with an alternative method of restraining by tape, kept for two weeks. We analyzed the morphometry of the diaphragm muscle fibers with hematoxylin/eosin staining. Statistical difference was found (p < 0.0001 when the average diameter of the diaphragm muscle fibers of immobilized animals (47.15μm ± 0.329μm was compared to the ones in the control group (54.67μm ± 0.396μm. Considering the results, it can be concluded that the immobilization of the animal paw in the used model was able to produce hypotrophy of respiratory musculature, as well as a general framework for reducing the mass of the animal.

  6. Differences among isolates of simian hemorrhagic fever (SHF) virus.

    Science.gov (United States)

    Gravell, M; London, W T; Leon, M E; Palmer, A E; Hamilton, R S

    1986-01-01

    Simian hemorrhagic fever (SHF) virus is a member of the Togaviridae family which currently is unclassified to genus. We have studied the relatedness of four different SHF virus isolates obtained from infected macaque or patas monkeys. Differences were found among isolates in type and severity of disease produced in patas monkeys, cell sensitivity to infection, viral antigens, and levels of specific antibody induced in patas monkeys. Based on these criteria, the four isolates have been grouped in two categories: those producing acute infections in patas monkeys (LVR, P-180) and those producing persistent infections (P-248, P-741). The P-180 isolate induced the most severe disease in experimentally infected patas monkeys, but only occasionally were their infections fatal. Persistently infected patas monkeys were viremic over a period of years, but showed no signs or symptoms of infection. All four isolates were found to be antigenically related by use of enzyme-linked immunosorbent assay (ELISA); the P-248 isolate showing the weakest antigenic relationship. However, none of the four isolates induced cross-neutralizing antibodies in infected patas monkeys. High titers of specific IgG antibody (up to 31,250 as determined by ELISA) were induced in acutely infected patas monkeys (LVR, P-180), but antibody was barely detectable (less than or equal to 50) in persistently infected patas monkeys (P-248, P-741). LVR lytically infected USU-104 cells, patas monkey peritoneal macrophages (PMAC), and rhesus monkey PMAC. The P-180 isolate lytically infected both patas monkey PMAC and rhesus monkey PMAC, but not USU-104 cells. The isolates producing persistent infections (P-248, P-741) lytically infected only rhesus monkey PMAC. These results show that marked differences exist among isolates of SHF virus from naturally infected animals. These differences should be useful in categorizing new isolates.

  7. Drogadicción, Fármaco-Dependencia o Drogadicción

    National Research Council Canada - National Science Library

    Mario Camacho Pinto

    1994-01-01

    .... En otros casos suele ser el refugio de sociópatas o psicópatas que, en busca de alivio para su insuficiencia, sufrimiento y rechazo, se constituyen en adictos e inductores con su ejemplo y requieren tratamiento, control...

  8. On how a dentist can also be a homeopath. Sobre cómo un cirujano dentista tambiém puede ser homeópata. Das formas do cirurgião-dentista ser também homeopata.

    Directory of Open Access Journals (Sweden)

    Ruth Barbosa

    2003-01-01

    Full Text Available No Brasil, a possibilidade de atuação conjunta entre Homeopatia e Odontologia iniciou-se no final do século passado, comprovando que trocar informações e conhecimento é prática indispensável entre profissionais responsáveis e visionários. A Homeopatia oferece ao cirurgião-dentista uma filosofia que expande e aprofunda a observação de seu paciente. Ao mesmo tempo, a Odontologia assessora a remoção de obstáculos mecânicos à cura, deixando ao observador homeopata apenas o que é característico e peculiar ao paciente no ambiente estomatoglossognato-cranio-cervical.

  9. Éxito reproductivo de los pájaros bobos patas azul, Sula nebouxii, y los pájaros bobos café, Sula leucogaster, como indicador de perturbación por uso turístico en las Islas Marietas, México

    Directory of Open Access Journals (Sweden)

    Cornejo–Ortega, J. L.

    2016-06-01

    Full Text Available Breeding success of the blue–footed booby, Sula nebouxii, and the brown booby, Sula leucogaster, as an indicator of touristic disturbance in the Islas Marietas, Mexico We studied the breeding success of two seabird species, the blue–footed booby, Sula nebouxii, and the brown booby, Sula leucogaster, in relation to touristic disturbance in order to focus conservation management strategies in the protected area of the Marietas Islands in Bahía de Banderas, Mexico. Data were collected throughout the breeding season of 2013 at Isla Larga. We considered three sites under different conditions of simulated disturbance within the colonies: ‘medium’, visits constrained to a single path; ‘high’, visits without spatial restrictions, and ‘low’, no visits. The total numbers of nests, eggs and chicks for each species were recorded weekly at the three sites. On the basis of these data, we determined the viability of eggs (hatching success and chicks. A generalized linear mixed model (GLIMMIX showed that breeding success (eggs–to–fledglings rate had no relationship to the conditions of the area and but was significantly lower in the blue–footed booby. The presence of tourists, as measured in this study, was not the cause of nesting failure. Other, non–evaluated factors likely play a role in limiting the breeding success of the two species of booby studied here.

  10. Inhibition of carrageenan-induced expression of tissue and plasma prekallikreins mRNA by low level laser therapy in a rat paw edema model Inibição da expressão de RNA mensageiro de pré-calicreínas tecidual e plasmática pela laserterapia em modelo de edema de pata induzido pela carragenina em ratos

    Directory of Open Access Journals (Sweden)

    Moisés P. Silva

    2011-02-01

    Full Text Available BACKGROND: Low level laser therapy (LLLT has been used clinically in order to treat inflammation, where tissue and plasma prekallikrein have crucial importance. Plasma prekallikrein (PPK is synthesized by the hepatocytes and secreted into the bloodstream, where it participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. Tissue prekallikrein is associated with important disease states (including cancer, inflammation, and neurodegeneration and has been utilized or proposed as clinically important biomarker or therapeutic target of interest. OBJECTIVE: To evaluate if LLLT modulates tissue and plasma prekallikreins mRNA expression in the carrageenan-induced rat paw edema. METHODS: Experimental groups were assigned as followed: A1 (Control-saline, A2 (Carrageenan-only, A3 (laser 660nm only and A4 (Carrageenan + laser 660nm. Edema was measured by a plethysmometer. Subplantar tissue was collected for the quantification of prekallikreins mRNA by Real time-Polymerase Chain Reaction. RESULTS: A significantly decrease in the edema was observed after laser irradiation. Expression of prekallikreins increased after carrageenan injection. Tissue and plasma prekallikrein mRNA expression significantly decreased after LLLT's 660nm wavelength. CONCLUSION: These results suggest that expression of tissue and plasma prekallikreins is modulated by LLLT, which can be used in clinical practice due to its anti-inflammatory effects.CONTEXTUALIZAÇÃO: A laserterapia de baixa potência tem sido usada para o tratamento de processos inflamatórios diversos em que a calicreína tecidual e a plasmática possuem participação ativa. A pré-calicreína plasmática (PPK é sintetizada pelos hepatócitos e secretada na corrente sanguínea, onde participa da ativação da coagulação, fibrinólise, geração de cininas e inflamação. A pré-calicreína tecidual está associada com importantes doenças (incluindo câncer, inflamação e neurodegeneração e tem sido utilizada ou sugerida clinicamente como importante biomarcador ou alvo terapêutico. OBJETIVO: Avaliar se a laserterapia altera a expressão gênica da pré-calicreína tecidual e da plasmática no modelo de inflamação aguda induzida pela carragenina. MÉTODOS: Quarenta ratos foram separados em quatro grupos experimentais: A1 (controle, A2 (carragenina, apenas, A3 (laser 660nm, apenas e A4 (Carragenina + laser 660nm. O edema foi medido por um pletismômetro. Tecido subplantar foi coletado para a quantificação de RNA mensageiro (RNAm de pré-calicreínas tecidual e plasmática por PCR em tempo real. RESULTADOS: Observou-se uma diminuição significativa no volume de edema após irradiação com laser 660nm. A expressão de RNAm de pré-calicreínas tecidual e plasmática aumentou após a inoculação de carragenina, entretanto a expressão gênica das pré-calicreínas diminuiu significantemente após laserterapia de baixa potência de 660nm. CONCLUSÃO: Os resultados sugerem que a expressão de RNAm das pré-calicreínas tecidual e plasmática é modulada pela laserterapia de baixa potência, podendo ser alvo terapêutico para tratamento de processos inflamatórios.

  11. Removal of suspended solids from the effluents of a shrimp farm by the Blood Ark Anadara tuberculosa (Sowerby, 1833 Remoción de sólidos suspendidos en los efluentes de una granja camaronera por la almeja pata de mula Anadara tuberculosa (Sowerby, 1833

    Directory of Open Access Journals (Sweden)

    Anselmo Miranda

    2009-08-01

    Full Text Available The potential of Anadara tuberculosa for bioremediation of shrimp farm effluents was evaluated in five field experiments performed in a semi-intensive shrimp farm in Sonora (NW Mexico, and yielded mean filtration, clearance and biodeposition rates of 33.10 mg/h/g, 0.41 L/h/g and 31.19 mg/h/g, respectively. This study demonstrates that A. tuberculosa adults can remove the particulate matter of a semi-intensive shrimp farms effluents.Se realizaron cinco experimentos en una granja de cultivo semi-intensivo de camarón ubicada en Sonora (Noroeste de México con el fin de verificar in situ el potencial de Anadara tuberculosa para la biorremediación de los efluentes de granjas camaroneras. Se obtuvieron tasas medias de filtración y de clarificación de 33.10 mg/h/g y 0.41 L/h/g y la de biodepositación fue 31.19 mg/h/g. Este estudio demuestra que individuos adultos de A. tuberculosa pueden remover la materia particulada de los efluentes de las granjas camaroneras semi-intensivas.

  12. Training of homeopathic physicians: current changes. Capacitación del médico homeópata: implementando cambios. A formação do médico homeopata: implementando mudanças.

    Directory of Open Access Journals (Sweden)

    Sandra Abrahão Chaim Salles

    2003-01-01

    Full Text Available Em nosso país, sendo a homeopatia reconhecida especialidade médica pelo Conselho Federal de Medicina desde 1980, a clínica homeopática em humanos deve ser praticada por médicos com especialização em homeopatia. A Associação Médica Homeopática Brasileira (AMHB, em convênio com a Associação Médica Brasileira (AMB, confere o título de especialista em homeopatia àqueles que, após cursarem a especialização, prestarem a prova para sua obtenção. Na verdade, outros profissionais, como dentistas, médicos veterinários e farmacêuticos, também podem se tornar homeopatas, contando também com a regulamentação de suas atividades pelas associações de cada categoria.

  13. New species of Haematoloechus (Digenea: Plagiorchidae in the lung of the foothill yellow-legged frog Rana boylii (Anura, from Humboldt County, California, USA Especie nueva de Haematoloechus (Digenea: Plagiorchidae del pulmón de la rana de patas amarillas Rana boylii (Anura, de Humboldt County, California, Estados Unidos de América

    Directory of Open Access Journals (Sweden)

    David Zamparo

    2011-06-01

    Full Text Available A new species of Haematoloechus is described from the lungs of Rana boylii from Humboldt County, California. The new species is similar to Haematoloechus buttensis, Haematoloechus kernensis, and Haematoloechus complexus in general course of the uterus and gonad shape. It is similar to H. buttensis by having a cirrus sac terminating midway between the posterior margin of the pharynx and the anterior margin of the ovary, and having a smaller oral/ventral sucker ratio; to H. complexus by having the genital pore ventral to the pharynx, and it is similar to H. kernensis by having a larger oral sucker to pharynx width ratio. The new species is unique by lacking an extra-cecal longitudinal uterine loop from the hind-body. Molecularly, the new species differs 1.04-1.15% in partial 28S sequence with respect to H. complexus, and a monophyletic grouping of these specimens in a phylogenetic analysis of all available sequence data consistent with the species-specific status proposed herein. Evidence is also presented to suggest that specimens identified as H. buttensis in Rana pretiosa from British Columbia, Canada represents a new, but still undescribed species. The importance of conducting biological inventories of helminths, along with continued monitoring of populations, and collections based taxonomy are related.Una especie nueva de Haematoloechus es descrita de los pulmones de Rana boylii de Humboldt County, California. La especie nueva guarda semejanza con Haematoloechus buttensis, Haematoloechus kernensis, y Haematoloechus complexus en la disposición general del útero y en la forma de las gónadas. Es similar a H. buttensis en que la bolsa del cirro finaliza entre el margen posterior de la faringe y el margen anterior del ovario, y en presentar una relación menor entre la ventosa oral y el acetábulo; a H. complexus por tener el poro genital ventral a la faringe, y a H. kernensis por tener una relación mayor del ancho de la ventosa oral contra la faringe. La especie nueva es única por carecer de asas uterinas extracecales longitudinales. Molecularmente, la especie nueva muestra 1.04-1.15% de diferencia en secuencias parciales de 28S con respecto H. complexus; esta información complementa las diferencias morfológicas. También se presenta evidencia para sugerir que ejemplares identificados como H. buttensis de Rana pretiosa en British Columbia, Canadá probablemente representan una especie nueva aún no descrita. Se aborda la importancia de la realización de inventarios biológicos de helmintos, el monitoreo continuo de las poblaciones y las colecciones basadas en la taxonomía.

  14. On the training of Brazilian homeopaths. Sobre la capacitación de los homeópatas brasileños. Sobre a formação dos homeopatas brasileiros.

    Directory of Open Access Journals (Sweden)

    Renato Sampaio Azambuja

    2007-01-01

    Full Text Available Although the credibility of homeopathy is raising among the Brazilian general population and government and academic institutions, the training of homeopaths disagrees with the exigences presented by clinical practice. This article discusses a proposal to reformulate the pedagogical practice, centered on the student as the builder of knowledge. The training basic block would be the small group, composed by students and a tutor; all activities would be performed in the concrete practice situation. The full process would unfold in three stages: 1 deconstruction of previous knowledge and establishment of new notions; 2 deepening into the homeopathic specific features; 3 discussion of homeopathy philosophical and epistemological issues, as well as its conection to related areas.

  15. Alodínia mecânica e edema de pata induzidos por um ativador da proteína quinase C, PDD:: caracterização e comparação com as respostas induzidas pela carragenina

    OpenAIRE

    2004-01-01

    A ativação da proteína quinase C (PKC) in vitro induz a liberação de mediadores inflamatórios e ativa ou sensibiliza os nociceptores. Estudos in vivo demonstraram que a ativação da PKC induz resposta inflamatória e está relacionada com o processamento espinhal e periférico da resposta nociceptiva. No entanto, uma caracterização da resposta nociceptiva e do edema induzidos pela injeção intraplantar (i.pl.) de um ativador da PKC em ratos ainda não foi conduzida. O presente estudo teve como obje...

  16. LEVEL OF CHOLESTEROL AND FATTY ACIDS IN THE EGGS OF DIFFERENT SPECIES OF POULTRY. TEORES DE COLESTEROL E ÁCIDOS GRAXOS EM OVOS DE DIFERENTES ESPÉCIES DE AVES

    Directory of Open Access Journals (Sweden)

    T. T. OLIVEIRA

    2008-08-01

    Full Text Available This work had as objective to evaluate the cholesterol level fatty acids of triacylglicerol and phosphofolipids of eggs of the different poultry species. The following results were observed: cholesterol: goose duck> turkey > chicken > quail. Fatty acids of triacylglicerols: palmitic acid: turkey > quail goose > duck chicken. Estearic acid: quail chicken> goose duck perua. Oleic acid : goose > chicken> quail duck turkey. α-Linoleic acid: chicken> turkey quail > goose duck. Arachidonic acid: turkey > quail duck> chicken> goose. Docosahexanoic acid: turkey> duck goose chicken > quail. Phospholipids of fatty acids: palmí]itic acid: duck> goose quail > chicken turkey. Estearic acid: chicken turkey > quail> goose > duck. Oleic acid: duck goose > quail > turkey> chicken. α-Linoleic acid: turkey > chicken quail > duck goose. Arachidonic acid: duck > goose > quail chicken > turkey. Docosahexanoic acid: chicken> goose > turkey> quail duck. These results can be of importance for food tables and dietetic treatment of patients.

    Este trabalho teve como objetivo avaliar o teor de colesterol, ácidos graxos de triacilgliceróis e de fosfolipídeos de ovos de diferentes espécies de aves. Foram observados os seguintes resultados: As concentrações de colesterol foram maiores na: pata ≅ gansa > perua > galinha > codorna. As concentrações de ácidos graxos de triacilgliceróis: ácido palmítico: perua> gansa codorna > galinha >pata. Ácido esteárico: codorna galinha > gansa pata perua. Ácido oléico: gansa > galinha >codorna pata perua. Ácido -linoléico: galinha >codorna > perua > gansa pata. Ácido araquidônico: perua > codorna pata > galinha> gansa. Ácido docosaexanóico: perua > pata gansa galinha > codorna. Ácidos graxos de fosfolipídeos: ácido palmítico: pata > gansa codorna > galinha perua. Ácido esteárico: galinha

  17. Protein (Cyanobacteria): 227779 [PGDBj - Ortholog DB

    Lifescience Database Archive (English)

    Full Text Available ZP_18822821.1 1117:4316 1118:2919 1125:192 1126:696 1160286:25 Putative peptidase PatA homolog (fragm...LSSFLNRIYYDLRNLGQTSQDRALNFAATNAFQAAQTFSEAVGAGMELDSINVSKSPFCRLDSDCWDVQLKFFDPENSRRARKVFRFTIDVSDLIPVTLGEVRSWSSPN ...

  18. Protein (Cyanobacteria): 227776 [PGDBj - Ortholog DB

    Lifescience Database Archive (English)

    Full Text Available ZP_18845350.1 1117:4316 1118:2919 1125:192 1126:696 1160285:784 Putative peptidase PatA homolog (fragm...FLNRIYYDLRNLGQTSQDRALNFAATNAFQAAQTFSEAVGAGMELDSINVSKSPFCRLDSDCWDVQLKFFDPENSRRARKVFRFTIDVSDLIPVTLGEVRSWSSPY ...

  19. Protein (Cyanobacteria): 227763 [PGDBj - Ortholog DB

    Lifescience Database Archive (English)

    Full Text Available ZP_10229400.1 1117:4316 1118:2919 1125:192 1160279:2410 Putative peptidase PatA homolog (fragm...ent) Microcystis sp. T1-4 MRRTLSSFLNRIYYDLRNLGQTSQDRALNFAATNAFQAAQTFSEAVGAGMELDSINVSKSPFCRLDSDCWDVQLKFFDPENSRRARKIFRFTIDVSDLIPVTLGEVRSWSSPY ...

  20. Estimation of Genetic Parameters for Main Wool Traits in Keerqin Fine Wool Sheep

    Institute of Scientific and Technical Information of China (English)

    Mei; Hua; Gao; Fengming

    2014-01-01

    [Objective]To investigate the population genetic structure of Keerqin fine wool sheep. [Method]The genetic parameters of wool traits in Keerqin fine wool sheep were calculated by employing paternal half sib correlation method. [Results]The traits with high heritability( h≥0. 3) included wool length( 1-year old),wool yield( 1-year old) and wool yield( 2-year old); that with medium heritability( 0. 1≤h≤0. 3) included wool fineness( 1-year old),wool fineness( 2-year old),wool length( 3-year old) and wool yield( 3-year old). There were extremely significant positive correlations between wool fineness( 1-year old) and wool fineness( 2-year old),between wool fineness( 1-year old) and wool fineness( 3-year old),between wool length( 1-year old) and wool length( 2-year old),between wool length( 1-year old) and wool length( 3-year old),and between wool fineness( 2-year old) and wool fineness( 3-year old),with the correlation coefficients of 0. 653 0,0. 625 8,0. 489 6,0. 578 8,0. 578 4 and 0. 554 6 respectively. The results showed that the phenotypic correlation was poorer than genetic correlation among the wool traits. [Conclusion]The wool fineness,wool yield and body weight of Keerqin fine wool sheep all fail to meet the excellent level and need to be improved further.

  1. Psicopatía, violencia y criminalidad: un análisis psicológico-forense, psiquiátrico-legal y criminológico (Parte II) Psychopathy, violence and crime: a psychological-forensic, psychiatric-legal and criminological analysis (Part II)

    OpenAIRE

    J.M. Pozueco Romero; S.L. Romero Guillena; N. Casas Barquero

    2011-01-01

    La Jurisprudencia española se encuentra frecuentemente ante dictámenes periciales en los que aparecen términos como psicópata, trastorno antisocial de la personalidad, personalidad psicopática, psicópata desalmado, psicopatía epileptoide, sociopatía, etc. De esta forma, no es infrecuente que los juristas (magistrados, jueces, fiscales, abogados) se hallen desorientados ante tanta terminología que, pese a todo, en absoluto se constituyen en sinónimos. La Doctrina, por su parte, disiente de la ...

  2. Drogadicción, Fármaco-Dependencia o Drogadicción

    OpenAIRE

    Mario Camacho Pinto

    1994-01-01

    La drogadicción puede considerarse como una enfermedad neuro-psico-social transmisible, cuya etiología más frecuente suele ser el vicio ambiental, consentido, voluntario, prevenible, que necesita adecuado control estatal.

    En otros casos suele ser el refugio de sociópatas o psicópatas que, en busca de alivio para su insuficiencia, sufrimiento y rechazo, se constituyen en adictos e inductores con su ejemplo y requieren tratamiento, control y rehabilitación estatal o p...

  3. Análisis de un algoritmo de control para un robot andador mediante simulación con ADAMS

    OpenAIRE

    Martín Torrejón, Víctor

    2011-01-01

    El objetivo principal de este proyecto es estudiar la robustez del algoritmo de control propuesto para un bípedo simple formado por dos patas actuadas desde un disco. Para ello se realizarán numerosas simulaciones con el programa Adams View del caminar del bípedo variando parámetros de control, como son el periodo y la amplitud de paso, así como el coeficiente de rozamiento entre las patas y el suelo. Objetivos secundarios que se desprenden de éste son: - Realizar una revisión del estado d...

  4. Delincuente sexual en serie y alteraciones psicopáticas: una relación ocasional Repeat sex offender and psychopathic changes: An incidental relationship

    OpenAIRE

    M. Ventura Alvarez; J.A. Presentación Blasco

    2003-01-01

    Los delincuentes sexuales en serie son tomados frecuentemente como psicópatas, en parte como consecuencia de la creciente popularidad del término. Un delincuente sexual en serie es aquel que ha actuado sobre dos o más víctimas en diferentes fechas; un psicópata es un tipo de trastorno de la personalidad que exhibe un patrón duradero de conductas socialmente irresponsables que desprecian los derechos de los demás. El presente trabajo presenta un caso de violador en serie interrumpido precozmen...

  5. Peptidoglycan Acetylation of Campylobacter jejuni Is Essential for Maintaining Cell Wall Integrity and Colonization in Chicken Intestines.

    Science.gov (United States)

    Iwata, Taketoshi; Watanabe, Ayako; Kusumoto, Masahiro; Akiba, Masato

    2016-10-15

    Peptidoglycan (PG) acetylation of Gram-positive bacteria confers lysozyme resistance and contributes to survival in the host. However, the importance of PG acetylation in Gram-negative bacteria has not been fully elucidated. The genes encoding putative PG acetyltransferase A (PatA) and B (PatB) are highly conserved in Campylobacter jejuni, the predominant cause of bacterial diarrhea worldwide. To evaluate the importance of PatA and PatB of C. jejuni, we constructed patA and patB isogenic mutants and compared their phenotypes with those of the parental strains. Although transmission electron microscopy did not reveal morphological changes, both mutants exhibited decreased motility and biofilm formation in vitro The extent of acetylation of the PG purified from the patA and patB mutants was significantly lower than the PG acetylation in the parental strains. Both mutants exhibited decreased lysozyme resistance and intracellular survival in macrophage cells. In a chick colonization experiment, significant colonization deficiency was observed for both mutants. These results suggest that PatA and PatB of C. jejuni play important roles in maintaining cell wall integrity by catalyzing PG O-acetylation and that the loss of these enzymes causes decreased motility and biofilm formation, thus leading to colonization deficiency in chicken infection. The importance of peptidoglycan (PG) acetylation in Gram-negative bacteria has not been fully elucidated. The genes encoding putative PG acetyltransferase A (PatA) and B (PatB) are highly conserved in Campylobacter jejuni, the predominant cause of bacterial diarrhea worldwide. We evaluated the importance of these enzymes using isogenic mutants. The results of this study suggest that PatA and PatB of C. jejuni play important roles in maintaining cell wall integrity. The loss of these factors caused multiple phenotypic changes, leading to colonization deficiency in chicken infection. These data should be useful in developing novel

  6. SO2 - Contribuer à une gestion plus efficace, démocratique, et responsable des services et des ressources dans les zone ciblées

    OpenAIRE

    Sene, A

    2004-01-01

    For a long time now, Pata has been a zone for migrant settlements. Over time, the migrants have joined the native populations who are mostly agro-pastoral Peuls. At the beginning of the recent migration flows of the 1970¿s, the Pata area was occupied by several ethnic groups¿with Peuls outnumbering the rest¿all engaged in agricultural and livestock activities to varying degrees. The state-controlled forest, despite the presence of some Peul hamlets (enclaves dating back to the 1950's), remain...

  7. Experiment list: SRX080343 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available toe fibroblast from apparently healthy 21 year old, 7% of the cells examined showing random chromosome loss/...1 year old || cell karyotype=7% of the cells examined showing random chromosome loss/gain -Coriell || cell l

  8. Methow River Steelhead - Methow River Steelhead hatchery reform research

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Steelhead in Pacific Northwest hatcheries are typically reared for release as 1-year-old smolts, rather than the 2and 3-year-old smolt life history patterns found in...

  9. Cougar predation and population growth of sympatric mule deer and white-tailed deer

    National Research Council Canada - National Science Library

    Robinson H.S; Wielgus R.B; Gwilliam J.C

    2002-01-01

    ...), recruitment, and cause-specific adult ( 1 year old) mortality rate for sympatric mule deer and white-tailed deer in south-central British Columbia to assess population growth for each species...

  10. Infecciones genitales por VPH tratadas por microinmunoterapia

    National Research Council Canada - National Science Library

    Jacques Grauwet, Diego

    2011-01-01

    ... genitales por VPH tratadas por microinmunoterapia Diego Jacques Grauwet Médico ginecólogo y homeópata, Madrid, España Recibido el 30 de mayo de 2010; aceptado el 10 de septiembre de 2011 Correo...

  11. Algklassilapsed vajavad teejuhti digimaailmas

    Index Scriptorium Estoniae

    2016-01-01

    Tartu ja Tallinna ülikooli teadlased arutasid metsaülikooli vestlusringis, kuidas nutiseadmeid koolitundides kasutada. Vestlusringis osalesid Kaido Reivelt Tartu Ülikoolist, Kai Pata Tallinna Ülikoolist ja Tuuli Hiiesalu Tartu Ülikoolist ning Tartu Luterliku Peetri koolist

  12. Arabidopsis CDS blastp result: AK243595 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK243595 J100084C06 At3g63200.1 68416.m07100 patatin-related low similarity to pata...tin-like latex protein allergen Hev b 7 - Hevea brasiliensis, EMBL:AF113546; contains patatin domain PF01734 1e-21 ...

  13. SJVS October 2012 correction

    African Journals Online (AJOL)

    HP USER

    As such the sizes of different segments of a .... educational, food market and abattoir premises) had ... Multi- purpose. Total. Transit area (vehicle terminals). 92 (7.3%). 86 (6.8%) 26 (2.1%) ... abattoir in the Central Pata Market area of Ilorin city.

  14. Atividades farmacológicas dos extratos de Zanthoxylum chiloperone (Rutaceae Pharmacological activities of Zanthoxylum chiloperone (Rutaceae extracts

    Directory of Open Access Journals (Sweden)

    Milcíades A. Villalba

    2007-06-01

    Full Text Available Neste trabalho foram avaliadas as atividades antinociceptiva e antiinflamatória dos extratos das folhas de Zanthoxylum chiloperone. Os ensaios foram realizados pelos testes de contorções abdominais induzidas por ácido acético, tempo da lambida da pata induzida por formalina, edema de pata e pleurisia induzidas por carragenina, usando os extratos hexânico, em acetato de etila e etanólico administrados nas doses de 100 e 200 mg/kg. As doses testadas reduziram, significativamente, as contorções abdominais, o tempo de lambida da pata, o edema de pata, o volume do exsudato e a migração leucocitária. Estes resultados sugerem que os extratos de Z. chiloperone possuem constituintes com atividades antinociceptiva e antiinflamatória.In this work the antinociceptive and anti-inflammatory activities of the extracts of leaves from Zanthoxylum chiloperone were evaluated. The tests were carried out by acetic acid writhing, formalin-induced paw licking, carrageenan-induced rat paw edema and pleurisy methods, using hexane, ethyl acetate and ethanol extracts administered in the doses of 100 and 200 mg/kg. The doses inhibited, significantly, the contortions, the paw lick, the paw edema, the volume of the exsudate and the leukocytes migration. These results suggest that the extracts from Z. chiloperone possess constituents with antinociceptive and anti-inflammatory activities.

  15. Singid letti! / Mari Kodres

    Index Scriptorium Estoniae

    Kodres, Mari

    2012-01-01

    Hispaania armastatuimast ja hinnatuimast toiduainest jamón ibérico'st ehk Ibeeria singist, mida tuntakse ka nime all pata negra (eesti k 'must sõrg'). Tammetõrudega toidetud Ibeeria sea lihast valmistatud parimad singid valmivad Loode-Andaluusias Sierra de Aracenas

  16. Putrescine catabolism is a metabolic response to several stresses in Escherichia coli.

    Science.gov (United States)

    Schneider, Barbara L; Hernandez, V James; Reitzer, Larry

    2013-05-01

    Genes whose products degrade arginine and ornithine, precursors of putrescine synthesis, are activated by either regulators of the nitrogen-regulated (Ntr) response or σ(S) -RNA polymerase. To determine if dual control regulates a complete putrescine catabolic pathway, we examined expression of patA and patD, which specify the first two enzymes of one putrescine catabolic pathway. Assays of PatA (putrescine transaminase) activity and β-galactosidase from cells with patA-lacZ transcriptional and translational fusions indicate dual control of patA transcription and putrescine-stimulated patA translation. Similar assays for PatD indicate that patD transcription required σ(S) -RNA polymerase, and Nac, an Ntr regulator, enhanced the σ(S) -dependent transcription. Since Nac activation via σ(S) -RNA polymerase is without precedent, transcription with purified components was examined and the results confirmed this conclusion. This result indicates that the Ntr regulon can intrude into the σ(S) regulon. Strains lacking both polyamine catabolic pathways have defective responses to oxidative stress, high temperature and a sublethal concentration of an antibiotic. These defects and the σ(S) -dependent expression indicate that polyamine catabolism is a core metabolic response to stress.

  17. Kenya's Monkeys

    Institute of Scientific and Technical Information of China (English)

    唐天麒

    2004-01-01

    It's difficult to get close to patas monkeys(花脸猴). Clever and nervous, they run away at the sight of humans. The long-legged monkeys, clocked ( 记录 [ 速度 ] ) at 34 miles an hour, easily escaped from the zoologist Lynne Isbell when she arrived in Kenya in 1992.

  18. Dharma Pātañjala : a Śaiva scripture from ancient Java : studied in the light of related old Javanese and Sanskrit texts

    NARCIS (Netherlands)

    Acri, Andrea

    2011-01-01

    My dissertation consists of three parts. Part I is an introduction to the Old Javanese-Sanskrit Śaiva text forming the main focus of the book, namely the Dharma Patañjala, which has been preserved on a palm-leaf codex unicus of West Javanese origin dating back to the 15th century AD. Part II presen

  19. Singid letti! / Mari Kodres

    Index Scriptorium Estoniae

    Kodres, Mari

    2012-01-01

    Hispaania armastatuimast ja hinnatuimast toiduainest jamón ibérico'st ehk Ibeeria singist, mida tuntakse ka nime all pata negra (eesti k 'must sõrg'). Tammetõrudega toidetud Ibeeria sea lihast valmistatud parimad singid valmivad Loode-Andaluusias Sierra de Aracenas

  20. Physical sciences: Thermodynamics, cryogenics, and vacuum technology: A compilation

    Science.gov (United States)

    1974-01-01

    Technological developments which have potential application outside the aerospace community are reported. A variety of thermodynamic devices including heat pipes and cooling systems are described along with methods of handling cryogenic fluids. Vacuum devices are also described. Pata et information is included.

  1. CMS Young Researchers Award 2013 and Fundamental Physics Scholars Award from the CMS Experiment

    CERN Multimedia

    Lapka, Marzena

    2014-01-01

    Photo 2: CMS Fundamental Physics Scholars (FPSs) 1st prize: Joosep Pata, from Estonian National Institue of Chemical Physics and Biophysics / Photo 1 and 3: CMS Young Researchers Award. From left to right: Guido Tonelli, Colin Bernet, Andre David, Oliver Gutsche, Dmytro Kovalskyi, Andrea Petrucci, Joe Incandela and Jim Virdee

  2. ELABORACIÓN DEL QUESO [Material gráfico

    OpenAIRE

    Anonymous

    2000-01-01

    LA QUESERA ES UN SOPORTE DE MADERA CON PATAS, CON FORMA INCLINADA Y UNAS CANALIZACIONES EN EL BORDE PARA QUE EL TABEFE ESCURRA. TRADICIONALMENTE LA ELABORACIÓN DEL QUESO SE HA RELACIONADO A LA MUJER PUES PARECE QUE LA MUJER CUENTA "CON UNA ESPECIAL DESTREZA Y PACIENCIA" NECESARIAS PARA SU ELABORACIÓN.

  3. Pediatric intracranial dural arteriovenous fistulas: age-related differences in clinical features, angioarchitecture, and treatment outcomes.

    Science.gov (United States)

    Hetts, Steven W; Moftakhar, Parham; Maluste, Neil; Fullerton, Heather J; Cooke, Daniel L; Amans, Matthew R; Dowd, Christopher F; Higashida, Randall T; Halbach, Van V

    2016-11-01

    OBJECTIVE Intracranial dural arteriovenous fistulas (DAVFs) are rare in children. This study sought to better characterize DAVF presentation, angioarchitecture, and treatment outcomes. METHODS Children with intracranial DAVFs between 1986 and 2013 were retrospectively identified from the neurointerventional database at the authors' institution. Demographics, clinical presentation, lesion angioarchitecture, treatment approaches, angiographic outcomes, and clinical outcomes were assessed. RESULTS DAVFs constituted 5.7% (22/423) of pediatric intracranial arteriovenous shunting lesions. Twelve boys and 10 girls presented between 1 day and 18 years of age; boys presented at a median of 1.3 years and girls presented at a median of 4.9 years. Four of 8 patients ≤ 1 year of age presented with congestive heart failure compared with 0/14 patients > 1 year of age (p = 0.01). Five of 8 patients ≤ 1 year old presented with respiratory distress compared with 0/14 patients > 1 year old (p = 0.0021). Ten of 14 patients > 1 year old presented with focal neurological deficits compared with 0/8 patients ≤ 1 year old (p = 0.0017). At initial angiography, 16 patients harbored a single intracranial DAVF and 6 patients had 2-6 DAVFs. Eight patients (38%) experienced DAVF obliteration by the end of treatment. Good clinical outcome (modified Rankin Scale score 0-2) was documented in 77% of patients > 1 year old at presentation compared with 57% of patients ≤ 1 year old at presentation. Six patients (27%) died. CONCLUSIONS Young children with DAVFs presented predominantly with cardiopulmonary symptoms, while older children presented with focal neurological deficits. Compared with other pediatric vascular shunts, DAVFs had lower rates of angiographic obliteration and poorer clinical outcomes.

  4. Aging affects mechanical properties and lubricin/PRG4 gene expression in normal ligaments.

    Science.gov (United States)

    Thornton, Gail M; Lemmex, Devin B; Ono, Yohei; Beach, Cara J; Reno, Carol R; Hart, David A; Lo, Ian K Y

    2015-09-18

    Age-related changes in ligament properties may have clinical implications for injuries in the mature athlete. Previous preclinical models documented mechanical and biochemical changes in ligaments with aging. The purpose of this study was to investigate the effect of aging on ligament properties (mechanical, molecular, biochemical) by comparing medial collateral ligaments (MCLs) from 1-year-old and 3-year-old rabbits. The MCLs underwent mechanical (n=7, 1-year-old; n=7, 3-year-old), molecular (n=8, 1-year-old; n=6, 3-year-old), collagen and glycosaminoglycan (GAG) content (n=8, 1-year-old; n=6, 3-year-old) and water content (n=8, 1-year-old; n=5, 3-year-old) assessments. Mechanical assessments evaluated total creep strain, failure strain, ultimate tensile strength and modulus. Molecular assessments using RT-qPCR evaluated gene expression for collagens, proteoglycans, hormone receptors, and matrix metalloproteinases and their inhibitors. While total creep strain and ultimate tensile strength were not affected by aging, failure strain was increased and modulus was decreased comparing MCLs from 3-year-old rabbits to those from 1-year-old rabbits. The mRNA expression levels for lubricin/proteoglycan 4 (PRG4) and tissue inhibitor of metalloproteinase-3 increased with aging; whereas, the mRNA expression levels for estrogen receptor and matrix metalloproteinase-1 decreased with aging. Collagen and GAG content assays and water content assessments did not demonstrate any age-related changes. The increased failure strain and decreased modulus with aging may have implications for increased susceptibility to ligament damage/injury with aging. Lubricin/PRG4 gene expression was affected by aging and its speculated role in ligament function may be related to interfascicular lubrication, which in turn may lead to altered mechanical function with aging and increases in potential for injury.

  5. Relation between phylogeny of African green monkey CD4 genes and their respective simian immunodeficiency virus genes

    DEFF Research Database (Denmark)

    Fomsgaard, Anders; Müller-Trutwin, Michaela C.; Diop, Ousmane

    1997-01-01

    An apparent species-specific relatedness of SIVagm suggests a coevolution with their natural hosts. However, the exact species or subspecies classification of African green monkeys, AGM, is uncertain because current classification schemes rely on phenotype markers, while more definitive genetic...... data are lacking. In this study, the CD4 protein involved in tissue type recognition was gentically cloned and sequence from PBMC RNA from all AGM species, including Barbados green monkeys (BGM). Phylogenetic trees were constructed that also included genomic CD4 nucleotide sequences from patas, sooty...... mangabeys, rhesus and pig-tail macaques, chimpanzees, and humans. Chimpanzees and humans consistently clustered together. Monkeys within the Cercopithecus genus formed a separate cluster which included pata monkeys, supporting its grouping as a member of Cercopithecus. Surprisingly, sooty mangabeys were...

  6. Development and Validation of an Exogenous Metabolic Activation System for FETAX

    Science.gov (United States)

    1997-06-01

    of in vivo assays. In a study conducted for NIH, the National Academy of Sciences recently concluded that the development and use of lower life form...National Institute of Environmental Health Sciences (NIEHS), have indicated that these groups are interested in the FETAX system, but would not use or...Schaefer Pat Lee Timothy Propst Brian Faulkner Curtis Mirkes Scott Shannon Tommy Wynn John Delphon Micheal Copenhaver 28 iW 4 AppendixA2 jRawv 2Pata

  7. Research in Biological and Medical Sciences, Including Biochemistry, Communicable Disease and Immunology, Internal Medicine, Nuclear Medicine, Physiology, Psychiatry, Surgery, and Veterinary Medicine. Volume 1

    Science.gov (United States)

    1975-07-01

    sera has been attempted using a variety of extraction procedures. Acetone and kaolin extraction failed to remove these inhibitors and silicic...M.C. and Sadun, E.H. Changes in lymphatic efficiency in filarial-infected Patas monkeys studied with ^^TC sulphur colloid. Nuclear...commonly used methods for nonspecific inhibitor removal; kaolin , (5) heparin-MnCl2 (6) and dextran sulfate - CaCl2 (7). This report introduces a new

  8. Mycorrhizal bioestimulation with essential oil on Enterolobium contorsiliquum and Bauhinia forficata seedlings in soil contaminated with copper

    Directory of Open Access Journals (Sweden)

    Rodrigo Ferreira da Silva

    2015-06-01

    Full Text Available The use of native tree species inoculated with ectomycorrhizal fungus can be an alternative for revegetation of soil contaminated with copper. The objective was to evaluate the interference of eucalyptus essential oil copper and ectomycorrhiza on growth and quality of seedlings timbaúva-preta (Enterolobium contorsiliquum and pata-de-vaca (Bauhinia forficata. The study was conducted in greenhouse for 120 days using as substrate the layer of 0-20 cm of a Red Oxisol with very clayey texture. The experimental design was completely randomized factorial (2 x 2 x 2, and “ with and without “ inoculant ectomycorrhizal essential oil and addition of 150 mg kg-1 of copper in the soil . Was evaluated the plant height, stem diameter, dry mass of shoots, roots and total length and specific surface area and root seedling quality of relations between: shoot height and stem diameter, shoot height and dry mass of shoots and the quality index of Dickson. The formation of ectomycorrhiza was identified by visualization of fungal structures and surface morphology internal and external morphology of the root system. Addition of copper reduced de stems diameter and dry mass of de aerial part of the pata-de-vaca seedlings regardless of the addition of inoculant and oil. There was no formation of ectomycorrhiza, even when applied in the essential oil of seedlings timbaúva-preta and pata-de-vaca. Growth of timbaúva-preta seedlings is stimulated by the addition of 150 mg kg – 1 of copper and has a higher rate of seedling quality in relation to pata-de-vaca.

  9. Un caso teratológico en Promesomachilis hispanica Silv., 1923 ( Apterygota: Microcoryphia )

    OpenAIRE

    Gaju-Ricart, Miguel; Bach de Roca, Carmen

    1987-01-01

    Se describe, en un ejemplar macho de Promesomachilis hispanica Silvestri, 1923 (Insecta, Apterygota: Microcoryphia), un caso de malformación corporal consistente en la aparición en el 2º par de patas (lado derecho), de un estilo coxal supernumerario. Comparados determinados parámetros del ejemplar en cuestión, con los de otros 16 machos adultos, no se han apreciado diferencias destacables entre los mismos.

  10. Complementary data on Haplozetes fusifer (Berlese, 1908 (Acari, Oribatida, Haplozetidae collected from Iran

    Directory of Open Access Journals (Sweden)

    Akrami, M. A.

    2013-12-01

    Full Text Available An oribatid mite of the family Haplozetidae, Haplozetes fusifer (Berlese, 1908 is redescribed on the basis of Iranian materials, including the first detailed descriptions of the gnathosoma and legs.Se redescribe un ácaro oribátido de la familia Haplozetidae, Haplozetes fusifer (Berlese, 1908, sobre la base de material iraní, incluyendo las primeras descripciones detalladas del gnatosoma y las patas.

  11. Evaluación neuropsicológica en internos penitenciarios mexicanos.

    Directory of Open Access Journals (Sweden)

    Nallely Arias García

    2010-07-01

    Full Text Available El objetivo de esta investigación fue evaluar psicológica y neuropsicológicamente a un grupo de internos violentos de una Penitenciaría Federal en México y caracterizarlos de acuerdo con la clasificación de impulsividad y premeditación de Barratt (Barratt, Stanford, Lynn, Liebman y Kent, 1999 y utilizando la clasificación de Hare (1991 de psicopatía, para analizar las diferencias entre los grupos de acuerdo a diferentes clasificaciones. La muestra fue integrada por 75 participantes, 50 internos y 25 controles para el estudio 1 (impulsivos vs premeditados y 54 sujetos para el estudio 2 (no psicópatas vs psicópatas. Se administraron la Escala de Impulsividad de Plutchik, el Inventario de Hostilidad de Buss-Durkee, la batería neuropsicológica NEUROPSI ATENCIÓN y MEMORIA (Ostrosky-Solís, Gómez, Ardila, Rosselli, Pineda y Matute; 2003 y la batería de Funciones Frontales y Ejecutivas (Flores, Ostrosky y Lozano, 2008. Los resultados indican que las poblaciones violentas independientemente de su clasificación pueden ser diferenciadas de la población no violenta. Sin embargo, no se encontraron diferencias significativas en las evaluaciones neuropsicológicas entre los grupos impulsivo y premeditado, mientras que los resultados entre los no psicópatas y psicópatas muestran diferencias significativas en distintos dominios cognoscitivos. Los resultados se discuten en términos de la base anatómica que subyace a dichos procesos.

  12. Herodot zur skythischen Sprache

    DEFF Research Database (Denmark)

    Hinge, George

    2005-01-01

    Herodots skythiske etymologier for fokenavnene Arimaspoi og Oiorpata må opgives ("enøjet" = arima "en" + spu "øje" og "manddræbende" = oior "mand" + pata "dræbe"). Artiklens forfatter foreslår i stedet nye skythiske forklaringer (*arjataspāh "hesterig" og *aiwawarakāta "enbrystet"). Herodots falske...... overbetydningen af sproget i Herodots historieværk....

  13. PHYTOCHEMICAL STUDY Bauhinia forficata (FABACEAE)

    OpenAIRE

    Simões, Ranggel Carvalho; Almeida, Sheylla Susan Moreira da Silva de

    2015-01-01

    The present study describes the results of preliminary phytochemical screening, Toxicological Artemia salina bioassay and antimicrobial activity in Bauhinia forficata link, known for popularly Pata-de-vaca. The Bauhinia is a pantropical genus, its species are used in the treatment of several infections and diseases, especially diabetes. The phytochemical prospection used crude ethanolic extract (EBE) of the stem bark of Bauhinia forficata Link; the toxicity analyses in Artemia salina for give...

  14. Simulación de un Robot Hexápodo Bioinspirado en el Tenebrio

    Directory of Open Access Journals (Sweden)

    Juan Pablo Rodríguez-Calderón

    2015-06-01

    Full Text Available Los insectos son base fundamental en el estudio de la robótica reactiva ya que estos poseen características biológicas y motrices que son de interés para ser implementadas en robots bioinspirados, teniendo en cuenta el desempeño de éstos en diferentes áreas. Por otra parte los animales hexápodos poseen omnidireccionalidad y estabilidad, debido a la formación del trípode de apoyo, el cual se crea en sus patas al dar un paso, lo cual les permite sobrepasar diferentes obstáculos con facilidad y velocidad constante. En este proyecto se implementa el sistema locomotor del insecto Tenebrio debido a la facilidad con que se pueden apreciar sus movimientos. Se analiza el desplazamiento de las patas del insecto en diferentes trayectorias, vistas y terreno plano, posteriormente se encontraron los parámetros, ecuaciones y restricciones que limitan los diferentes eslabones de cada una de las patas del Tenebrio, esto se realizó por medio de un análisis de imágenes. Finalmente la información recogida se implementa en la plataforma MATLAB para determinar las características de movimiento, estabilidad y desplazamiento.

  15. Biased inheritance of the protein PatN frees vegetative cells to initiate patterned heterocyst differentiation.

    Science.gov (United States)

    Risser, Douglas D; Wong, Francis C Y; Meeks, John C

    2012-09-18

    Heterocysts, cells specialized for nitrogen fixation in certain filamentous cyanobacteria, appear singly in a nonrandom spacing pattern along the chain of vegetative cells. A two-stage, biased initiation and competitive resolution model has been proposed to explain the establishment of this spacing pattern. There is substantial evidence that competitive resolution of a subset of cells initiating differentiation occurs by interactions between a self-enhancing activator protein, HetR, and a diffusible pentapeptide inhibitor PatS-5 (RGSGR). Results presented here show that the absence of a unique membrane protein, PatN, in Nostoc punctiforme strain ATCC 29133 leads to a threefold increase in heterocyst frequency and a fourfold decrease in the vegetative cell interval between heterocysts. A PatN-GFP translational fusion shows a pattern of biased inheritance in daughter vegetative cells of ammonium-grown cultures. Inactivation of another heterocyst patterning gene, patA, is epistatic to inactivation of patN, and transcription of patA increases in a patN-deletion strain, implying that patN may function by modulating levels of patA. The presence of PatN is hypothesized to decrease the competency of a vegetative cell to initiate heterocyst differentiation, and the cellular concentration of PatN is dependent on cell division that results in cells transiently depleted of PatN. We suggest that biased inheritance of cell-fate determinants is a phylogenetic domain-spanning paradigm in the development of biological patterns.

  16. Orbital lymphomatoid granulomatosis - a rare cause of proptosis

    Energy Technology Data Exchange (ETDEWEB)

    Du Toit, Jacqueline; Kilborn, Tracy [Department of Radiology, Red Cross Children' s Hospital, Rondebosch (South Africa); Eyssen, Ann van [Department of Oncology, Red Cross Children' s Hospital, Rondebosch (South Africa); Pillay, Komala [Department of Pathology, Red Cross Children' s Hospital, Rondebosch (South Africa)

    2015-07-15

    A 1-year-old girl with unilateral proptosis was found to have primary orbital lymphomatoid granulomatosis - a condition rarely occurring in children. This multisystem angiocentric, angiodestructive, lymphoproliferative disease typically involves the lungs, with ocular involvement being extremely uncommon. Our case serves to illustrate the imaging findings of this unusual condition and highlight a rare cause of proptosis. (orig.)

  17. Rectal diaphragm in a patient with imperforate anus and rectoprostatic fistula

    Directory of Open Access Journals (Sweden)

    Thakur Ashokanand

    2009-01-01

    Full Text Available The association of rectal diaphragm in an imperforate anus has not been reported until now. A 1-year-old male presented with right transverse colostomy for high anorectal malformation. The patient had imperforate anus and a recto-prostatic fistula with rectal diaphragm. We managed the case by an ano-rectal pull through with excision of the diaphragm.

  18. 17-Beta estradiol and 4-nonylphenol delay smolt development and downstream migration in Atlantic salmon, Salmo salar

    DEFF Research Database (Denmark)

    Madsen, Steffen S; Skovbølling, Søren; Nielsen, Christian;

    2004-01-01

    The effect of 17-beta estradiol (E2) and 4-nonylphenol (4-NP) on smoltification and downstream migration of Atlantic salmon was studied in an integrated laboratory and field study. In a stock of hatchery-raised 1-year-old salmon, smoltification progressed from February until late May as judged...

  19. Investigation of the pathogenesis of transplacental transmission of Aleutian mink disease parvovirus in experimentally infected mink

    DEFF Research Database (Denmark)

    Broll, S.; Alexandersen, Søren

    1996-01-01

    The transplacental transmission of Aleutian mink disease parvovirus (ADV) was studied in experimental infection of 1-year-old female non-Aleutian mink. The ADV-seronegative female mink were inoculated,vith ADV prior to mating or after the expected implantation of the embryos during pregnancy...

  20. Cow's milk and children

    Science.gov (United States)

    Milk and children; Cow’s milk allergy - children; Lactose intolerance - children ... You may have heard that cow's milk should not be given to babies younger than 1 year old. This is because cow's milk doesn't provide enough of certain ...

  1. Aircraft/Stores Compatibility Symposium Proceedings, Held at Arlington, Virginia on 2-4 September 1975. Volume 2

    Science.gov (United States)

    1975-01-01

    technical leadership in development of sensor systems. Mr. Pertman is married and has three children , 8, 2, and 1 year old. He enjoys chess, reading...requirements of interface circuits peculiar to an individual store. 6. Suplemental Equipment Used do document additional Signal Logic (NOW Fbrmat

  2. 数字解读(英文)

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    74.1 Years Old A reporter with Xinhua News Agency recently obtained information,from the Office of the National Working Committee on Children and Women,which indicated the average life expectancy of Chinese women has risen from 73.3 years,in 2000,to the current 74.1 years.

  3. SAMJ 8842.indd

    African Journals Online (AJOL)

    functional terms on a child's learning potential. ... support. Two short case scenarios and a letter from an educator ... When he was 1 year old, HIVE was diagnosed and he was enrolled ... school in a class of 8 children. ... independently at 2 years, 7 months. ... low average, visual memory borderline, and executive functioning.

  4. Effect of spatial differences in growth on distribution of seasonally co-occurring herring Clupea harengus stocks

    DEFF Research Database (Denmark)

    Worsøe Clausen, Lotte; Stæhr, Karl-Johan; Rindorf, Anna

    2015-01-01

    over time. Contrary to previous perception of the juvenile migration, NSAS were found to leave the study area at the age between 1 and 2 years and WBSS 1 year olds were encountered in the Skagerrak. The estimated parameters of von Bertalanffy growth equations showed marked differences between areas...

  5. Aggression and dominance in matched groups of subadult Icelandic horses (Equus caballus)

    NARCIS (Netherlands)

    Vervaecke, H.; Stevens, J.M.G.; Vandemoortele, H.; Sigurjónsdóttir, H.; Vries, Han de

    2006-01-01

    We studied sex differences in the nature of aggression and dominance behaviour in two newly formed groups of 1-year-old Icelandic horses. One herd contained nine geldings, the other nine mares. The groups were matched with regard to dominancedetermining traits such as age, weaning age, composition o

  6. Creating an Amazing Montessori Toddler Home Environment

    Science.gov (United States)

    Woo, Stephanie

    2014-01-01

    The author states that raising her twins the Montessori way has made her life easy. Imagine two 1-year-olds eating entire meals on their own, setting their own tables by 20 months, and becoming potty-trained before 2. These are not statistics found in just one household. Children raised the Montessori way can take care of themselves and their…

  7. A stand-development approach to oak afforestation in the lower Mississippi alluvial valley

    Science.gov (United States)

    Brian Roy Lockhart; Emile Gardiner; Theodor Leininger; John Stanturf

    2008-01-01

    Oak (Quercus spp.) afforestation in the Lower Mississippi Alluvial Valley has involved planting 1-year-old bareroot seedlings on a relatively wide spacing in single-species stands or planting light-seeded species with oaks to form mixed-species stands. In the former case, the developing single-species stands have limited future management options...

  8. Cardiofaciocutaneous syndrome: A rare entity

    Directory of Open Access Journals (Sweden)

    S Pavithra

    2012-01-01

    Full Text Available The cardiofaciocutaneous (CFC syndrome is a condition of sporadic occurrence, with patients showing multiple congenital anomalies and mental retardation and characteristic dysmorphic features. We, thus, report a rare case of this syndrome in a 1-year-old child who presented with typical features of CFC syndrome.

  9. Detection of Bordetella pertussis using a PCR test in infants younger than one year old hospitalized with whooping cough in five Peruvian hospitals

    Directory of Open Access Journals (Sweden)

    María Esther Castillo

    2015-12-01

    Conclusion: An increase in pertussis cases has been reported in recent years in Peru, despite national immunization efforts. Surveillance with PCR for B. pertussis is essential, especially in infants less than 1 year old, in whom a higher rate of disease-related complications and higher mortality have been reported.

  10. Hearing Evaluation in Children (For Parents)

    Science.gov (United States)

    ... Lessons? Visit KidsHealth in the Classroom What Other Parents Are Reading Your Child's Development (Birth to 3 Years) Feeding Your 1- ... Year-Old Hearing Evaluation in Children KidsHealth > For Parents > Hearing Evaluation in Children A A A What's in this article? Causes ...

  11. One-Year-Olds Think Creatively, Just Like Their Parents

    Science.gov (United States)

    Hoicka, Elena; Mowat, Rachael; Kirkwood, Joanne; Kerr, Tiffany; Carberry, Megan; Bijvoet-van den Berg, Simone

    2016-01-01

    Creativity is an essential human ability, allowing adaptation and survival. Twenty-nine 1-year-olds and their parents were tested on divergent thinking (DT), a measure of creative potential counting how many ideas one can generate. Toddlers' and parents' DT was moderately to highly correlated. Toddlers showed a wide range of DT scores, which were…

  12. Bypass flow and its role in leaching of raised beds under different land use types on an acid sulphate soil.

    NARCIS (Netherlands)

    Minh, L.Q.; Tuong, T.P.; Booltink, H.W.G.; Mensvoort, van M.E.F.; Bouma, J.

    1997-01-01

    A better understanding of leaching processes in raised beds is useful in assessing management options for acid sulphate soils. Field and laboratory studies were carried out to quantify the effects of soil physical properties and bypass flow on leaching processes of new, 1-year-old and 2-year-old rai

  13. Feeding mink (Neovison vison) a protein-restricted diet during pregnancy induces higher birth weight and altered hepatic gene expression in the F2 offspring

    DEFF Research Database (Denmark)

    Matthiesen, Connie Marianne Frank; Blache, Dominique; Thomsen, Preben Dybdahl

    2010-01-01

    Malnutrition during foetal life can induce modifications in the phenotype of an individual. The present study aimed to observe effects of low foetal life protein provision on modifications of the phenotype and changes in the progeny of 1-year-old female mink (F1 generation) offspring of mothers f...

  14. Mentors in Life and at School: Impact on Undergraduate Protege Perceptions of University Mission and Values

    Science.gov (United States)

    Ferrari, Joseph R.

    2004-01-01

    University undergraduates (84 women, 80 men: M age=19.1 years old) reported school mission and value perceptions, life and/or school mentor relationships, and social desirability tendencies. No significant social desirability effect was obtained. Proteges with mentors at school and in life (n=52) reported greater cognitive and informational…

  15. Creating an Amazing Montessori Toddler Home Environment

    Science.gov (United States)

    Woo, Stephanie

    2014-01-01

    The author states that raising her twins the Montessori way has made her life easy. Imagine two 1-year-olds eating entire meals on their own, setting their own tables by 20 months, and becoming potty-trained before 2. These are not statistics found in just one household. Children raised the Montessori way can take care of themselves and their…

  16. TETRASOMY-5P MOSAICISM IN A BOY WITH DELAYED GROWTH, HYPOTONIA, MINOR ANOMALIES, AND AN ADDITIONAL ISOCHROMOSOME-5P [46,XY/47,XY,+I(5P)

    NARCIS (Netherlands)

    SIJMONS, RH; LEEGTE, B; VANLINGEN, RA; DEPATER, JM; VANDERVEEN, AY; DELCANHO, H; TENKATE, LP; BREED, ASPM

    1993-01-01

    We describe a 1-year-old boy with a rare de novo 46,XY/47,XY,+ i(5p) mosaicism (ratios 28/3 in peripheral blood lymphocytes and 2/12 in skin fibroblasts). The boy, born after a pregnancy of 34 weeks, had lung hypoplasia, persistent hypotonia, and postnatal growth failure. Craniofacial anomalies were

  17. CARDIAC AND BEHAVIORAL-RESPONSES OF LONG-TERM OBESE AND LEAN ZUCKER RATS TO EMOTIONAL-STRESS

    NARCIS (Netherlands)

    NYAKAS, C; BALKAN, B; STEFFENS, AB; BOHUS, B

    1995-01-01

    Obesity is known as a risk factor in stress-related cardiovascular pathology in man. The length of obesity can be an important interacting variable. Therefore, cardiac and behavioral responses to emotional stress were studied in 1-year-old, genetically obese (fa/fa) and lean (Fa/-) male Zucker rats,

  18. Digital Childhood

    Institute of Scientific and Technical Information of China (English)

    Wang Hairong

    2012-01-01

    Three-year-old Li Ming is a restless boy in Beijing,but one thing that always calms him down is an iPad.Like many young children in China,Li has been exposed to electronic products almost from birth.When he was about 1 year old,his mother began showing him animated children's songs on a computer.

  19. Root desiccation and drought stress responses of bareroot Quercus rubra seedlings treated with a hydrophilic polymer root dip

    Science.gov (United States)

    Kent G. Apostol; Douglass F. Jacobs; R. Kasten Dumroese

    2009-01-01

    Root hydrogel, a hydrophilic polymer, has been used to improve transplanting success of bareroot conifer seedlings through effects on water holding capacity. We examined mechanisms by which Terra-sorb Fine Hydrogel reduces damage that occurs when roots of 1-year old, dormant northern red oak (Quercus rubra L.) were subjected to shortterm (1, 3, and 5...

  20. 7 CFR 4279.29 - Eligible lenders.

    Science.gov (United States)

    2010-01-01

    ...; audited financial statements not more than 1 year old; sources of funds for the proposed loans; office... 7 Agriculture 15 2010-01-01 2010-01-01 false Eligible lenders. 4279.29 Section 4279.29 Agriculture... UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE GUARANTEED LOANMAKING General § 4279.29 Eligible lenders....

  1. Bypass flow and its role in leaching of raised beds under different land use types on an acid sulphate soil.

    NARCIS (Netherlands)

    Minh, L.Q.; Tuong, T.P.; Booltink, H.W.G.; Mensvoort, van M.E.F.; Bouma, J.

    1997-01-01

    A better understanding of leaching processes in raised beds is useful in assessing management options for acid sulphate soils. Field and laboratory studies were carried out to quantify the effects of soil physical properties and bypass flow on leaching processes of new, 1-year-old and 2-year-old

  2. [Extreme dietary selectivity following liver transplantation in a 5-year-old girl; management via behavior therapy

    NARCIS (Netherlands)

    Moor, J.M.H. de; Brons, E.; Kokke, F.T.; Vos, H.; Tolboom, J.J.M.

    2004-01-01

    In a 5.1-year-old girl who had been treated by surgical correction of biliary atresia and total orthotopic liver transplantation, extreme dietary selectivity was noted; this was treated by behaviour therapy. On entry in the rehabilitation centre, she manifested malnutrition along with a variety of g

  3. Psychosocial Aspects of Cleft Lip and Palate: Implications for Parental Education. Research Report 138.

    Science.gov (United States)

    Kalland, Mirjam

    This study focused on the psychosocial aspects of cleft lip and/or palate on maternal emotional reactions and the family, with emphasis on the effect on the maternal-infant bond. Interviews were conducted with 40 mothers of 1-year-old infants with non-syndromic cleft lip and/or palate. The interviews were analyzed using the phenomenological…

  4. CARDIAC AND BEHAVIORAL-RESPONSES OF LONG-TERM OBESE AND LEAN ZUCKER RATS TO EMOTIONAL-STRESS

    NARCIS (Netherlands)

    NYAKAS, C; BALKAN, B; STEFFENS, AB; BOHUS, B

    1995-01-01

    Obesity is known as a risk factor in stress-related cardiovascular pathology in man. The length of obesity can be an important interacting variable. Therefore, cardiac and behavioral responses to emotional stress were studied in 1-year-old, genetically obese (fa/fa) and lean (Fa/-) male Zucker rats,

  5. Efeito analgésico de longa duração da dipirona sobre a hiperalgesia persistente induzida pela constrição do nervo ciático em ratos: participação do óxido nítrico Long term analgesic effect of dipyrone on the persistent hyperalgesia induced by chronic constriction injury of sciatic nerve in rats: involviment of nitric oxide

    Directory of Open Access Journals (Sweden)

    Fábio José Reis

    2006-12-01

    Full Text Available O efeito analgésico de longa duração da dipirona foi avaliado em um modelo de dor neuropática assim como a participação da via óxido nítrico-GMPc neste mecanismo analgésico. Uma única administração intraplantar de dipirona (80 µg, no 14º dia após a instalação da hiperalgesia neuropática induzida pela constrição do nervo ciático exerceu um efeito analgésico, significativo e de longa duração. A inibição da óxido nítrico sintetase com L-NAME (50 ou 100 µg/pata, ou do óxido nítrico (NO endógeno com hemoglobina (10 ou 30 µg/pata, bloquearam o desenvolvimento do efeito analgésico da dipirona. A L-arginina (500 µg/pata reverteu o efeito do L-NAME. Cloreto de metiltionínio (azul de metileno (500 µg/pata, ODQ (50 µg/pata (bloqueadores da guanilil ciclase ou glibenclamida (100, 200 ou 300 µg/pata (bloqueador de canais de K+ sensíveis ao ATP inibiram o efeito analgésico da dipirona. O nitroprussiato de sódio administrado no 14º dia após a instalação da hiperalgesia neuropática também exerceu efeito analgésico de longa duração, semelhante ao observado com a dipirona. Sugerimos que a ação analgésica periférica e de longa duração da dipirona, neste modelo experimental, ocorra devido a provável dessensibilização dos nociceptores, envolvendo a via óxido nítrico - GMPc e canais de K+ sensíveis ao ATP.The long term analgesic effect of dipyrone was evaluated on a model of neuropathic pain and the role of nitric oxide/GMPc pathway in this antinociceptive mechanism. One intraplantar dipyrone administration (80 mg, at 14th day after the chronic constriction injury of the sciatic nerve, induced a significant and long term analgesic effect. The inhibition of nitric oxide synthase (NOS with L-NAME (50 or 100 mg/paw or scavenging of the endogenous NO with hemoglobin (10 or 30 mg/paw inhibited the development of the dipyrone analgesia. L-arginine (500 mg/paw could reverted the effect of L-NAME. Metylene blue

  6. Using an experimental model for the study of therapeutic touch Uso de un modelo experimental para estudio sobre el toque terapéutico Utilização de um modelo experimental para estudo sobre o toque terapêutico

    Directory of Open Access Journals (Sweden)

    Daniella Soares dos Santos

    2013-02-01

    Full Text Available OBJECTIVE: to verify whether the Paw Edema Model can be used in investigations about the effects of Therapeutic Touch on inflammation by measuring the variables pain, edema and neutrophil migration. METHOD: this is a pilot and experimental study, involving ten male mice of the same genetic strain and divided into experimental and control group, submitted to the chemical induction of local inflammation in the right back paw. The experimental group received a daily administration of Therapeutic Touch for 15 minutes during three days. RESULTS: the data showed statistically significant differences in the nociceptive threshold and in the paw circumference of the animals from the experimental group on the second day of the experiment. CONCLUSION: the experiment model involving animals can contribute to study the effects of Therapeutic Touch on inflammation, and adjustments are suggested in the treatment duration, number of sessions and experiment duration.OBJETIVO: verificar si el Modelo de Edema de Pata puede ser utilizado en las investigaciones acerca de los efectos del Toque Terapéutico sobre la inflamación, mensurándose las variables dolor, edema y migración de neutrófilos. MÉTODO: se trata de un estudio piloto, experimental, con 10 ratones machos del mismo linaje genético, divididos en grupo experimental y control, sometidos a inducción química de inflamación local en la pata derecha trasera. O grupo experimental recibió una aplicación diaria de Toque Terapéutico con duración de quince minutos, por tres días. RESULTADOS: Los datos evidenciaron diferencias estadísticamente significativas en el umbral de nocicepción y circunferencia de las patas de los animales del grupo experimental durante el segundo día del experimento. CONCLUSIÓN: El modelo de experimento con animal puede contribuir al estudio de los efectos del Toque Terapéutico sobre la inflamación: se sugiere ajuste en el tiempo de exposición, número de sesiones y

  7. Psicopatía, violencia y criminalidad: un análisis psicológico-forense, psiquiátrico-legal y criminológico (Parte I Psychopathy, violence and crime: a psychological-forensic, psychiatric-legal and criminological analysis (Part I

    Directory of Open Access Journals (Sweden)

    J.M. Pozueco Romero

    2011-09-01

    Full Text Available Tras más de 200 años de historia, el concepto de "psicopatía" ha venido experimentando una auténtica y variopinta metamorfosis terminológica. Exceptuando aquellos períodos del Medievo en los que se creía que la psicopatía y cualquier otra conducta y personalidad "anormales" eran bien de origen demoníaco, bien de corte estrictamente hereditarista-biologicista-fisionomista-antropométrico, el resto de enfoques teórico-investigadores han arrojado sobrada luz que, a día de hoy, y tras más de 200 años de historia amarga y controvertida sobre el término, nos permiten haber llegado a un consenso generalizado entre los estudiosos de la psicopatía desde el punto de vista clínico-forense y criminológico. Este primer trabajo o Parte I es una revisión en la que se pretende ahondar en los polémicos y muchas veces incomprobables orígenes del término "psicopatía". Por otro lado, y tras intensas investigaciones empíricas realizadas desde los años 70 y centradas fundamentalmente en la población penitenciaria, modernamente se ha comenzado a hablar, de manera distintiva, tanto de los psicópatas criminales como de los psicópatas integrados, habiéndose hallado que la diferencia principal entre ambos tipos de psicópatas estriba, sencillamente, en la concreta comisión de delitos, puesto que la estructura básica de personalidad es prácticamente la misma en ambos tipos de psicópatas. Finalmente, se hace muy necesario subrayar que el carácter antisocial de la personalidad y conducta se observa, por definición, en cualquier tipo de delincuentes, sean éstos o no psicópatas, un carácter antisocial que, por otro lado, no siempre ni necesariamente se observa entre los denominados psicópatas integrados.After more than 200 years of history, the concept of "psychopathy" has been undergoing an authentic and varied terminological metamorphosis. Except for those periods in the Medieval Age in which it was believed that psychopathy and other

  8. Efeito do meloxicam sobre a lesão de isquemia e reperfusão em músculo esquelético de ratos Effect of meloxicam on ischemia-reperfusion injury in skeletal muscle of rats

    Directory of Open Access Journals (Sweden)

    Vitor A. Uhle

    2000-01-01

    Full Text Available Os antiinflamatórios não esteroidais, derivados do piroxicam, agem como varredores de radicais livres de oxigênio em experimentos in vitro. O objetivo deste trabalho foi analisar o efeito do meloxicam em músculos esqueléticos de ratos submetidos à isquemia e reperfusão com base na análise de liberação de malondialdeído da membrana celular ( indicador de peroxidação lipídica provocada pelos radicais livres. Dezoito ratos Wistar foram divididos em 2 grupos de 9. O grupo I (grupo sham foi tratado previamente com 3g/kg de peso de solução fisiológica e o grupo II com 3g/kg de peso de meloxicam por via peritoneal. Após 5 min os ratos foram submetidos a 3h de isquemia total ( torniquete e 45 min de reperfusão das patas posteriores esquerdas. Colheram-se biópsias dos músculos isquêmicos e reperfundidos e das patas controles (contralaterais para a dosagem de malondialdeído. A análise das diferenças de concentração do malondiadeído nas patas controles e reperfundidas no grupo I (43,7± 60,7; n=9 em relação ao grupo II (21,7± 49,5; n=9 não mostrou alteração significante (p=0,3. Os dados obtidos, neste trabalho, mostram que o meloxicam não protege a musculatura esquelética dos danos causados pela isquemia e reperfusão, com base na análise do malondialdeído tissular após 3h de isquemia e 45 min de reperfusão.

  9. Influência do método de osteotomia para preparação do leito na reparação óssea ao redor de implantes de titânio: comparação histológica entre instrumento rotatório e ultrassom cirúrgico piezoelétrico

    OpenAIRE

    Marcelo Sirolli Ferreira

    2014-01-01

    O objetivo deste estudo foi avaliar histomorfometricamente a influência da piezocirurgia (PZ) sobre a reparação óssea ao redor de implantes de titânio. Foram utilizados 15 ratos machos Wistar, com aproximadamente 300g, nos quais em uma das patas o leito para instalação de um implante de titânio foi realizado com um motor rotatório convencional (Grupo Controle) e na outra com ultrassom cirúrgico piezoelétrico (Grupo Piezo). Após 30 dias, os animais foram sacrificados para obtenção do material ...

  10. Tratamiento quirúrgico de algunos trastornos mentales

    OpenAIRE

    Lourído-Albán, Francisco A.

    2012-01-01

    La mayoría de los autores están acordes en considerar la Leucotomía Profesional como reservada a los casos de mal pronóstico y como la última carta a jugar (Trelles), para tratar de curar algunos síntomas como el dolor mental, la ansiedad y la tensión angustiosa, con base en el sacrificio de la personalidad del individuo pues "la leucotomía mejora pero no transforma al psicópata en individuo normal" (Fleming). Según Reitman, la leucotomía pre-frontal provoca alteraciones regresivas de la pers...

  11. Forma paraplégica de tétano associada a lesão medular pregressa

    Directory of Open Access Journals (Sweden)

    Roberto Melaragno

    1958-06-01

    Full Text Available Apresentação de um caso de forma paraplégica de tétano, com ponto de partida no pé, verificada em paciente portador de lesão medular pregressa (inflamatória? desmielinizante?. Os autores levantam a hipótese de que seu caso seria a reprodução, na patologia humana, das conclusões experimentais de Meyer, Ranson e outros, que conseguiram limitar o tétano aos membros posteriores de animais de laboratório quando, previamente à injeção de toxina na pata posterior, seccionavam a medula espinal.

  12. Taller "Cuerpo, movimiento y género"

    OpenAIRE

    Gonzalez Seligra, Ana; Vignolles, Diana

    2013-01-01

    Este taller surge a partir de la experiencia transitada por dos integrantes del Grupo Turuleca Danza en la realización de la obra Que las Parió de las Patas y la creación del proyecto Jams de Movimiento oeste. A lo largo de la experiencia del proceso creativo de la obra y el transitar de los jams de Movimiento se generó un diálogo desde lo teóricopractico sobre los conceptos: Cuerpo, Movimiento y Género. Este taller es parte del trabajo de investigación que se encuentran realizando con res...

  13. A síndrome anserina Anserine syndrome

    OpenAIRE

    2010-01-01

    Dor no joelho é uma condição comum na clínica diária e a patologia anserina, também conhecida como pata de ganso, tem sido considerada uma das principais causas. O diagnóstico tem sido realizado de maneira eminentemente clínica, o que tem gerado equívocos. Os pacientes queixam-se tipicamente de dor na parte medial do joelho, com sensibilidade na porção ínferomedial. Estudos de imagem têm sido realizados para esclarecer se tais pacientes possuem bursite, tendinite ou ambos os distúrbios na reg...

  14. Resultados de la cirugía del LCA : platias mixtas biológicas-sintéticas

    OpenAIRE

    2012-01-01

    Se estudian 58 casos de lesiones de ligamento cruzado anterior (LCA), aisladas o combinadas que dan lugar a inestabilidad anterior de la rodilla. Se realizan reconstrucciones intraarticulares con plastia mixta de tendones de la pata de ganso con aumento de fibra sintética de polipropileno trenzado (Kennedy-Lad) o de poliester de polietilenotereftalato (Leeds-Keio), durante el periodo comprendido entre 1988-1992, con un seguimiento mínimo de dos años. Las dos técnicas difieren en el paso artic...

  15. La crisis de la Monarquía Hispánica en la intendencia de Arizpe. Insurgencia y contrainsurgencia

    OpenAIRE

    Medina Bustos, José Carlos; Borrero Silva, María del Valle

    2012-01-01

    En este artículo se analiza el levantamiento de Miguel Hidalgo en la intendencia de Arizpe, provincia fronteriza de la Nueva España. Se destaca la importancia que tuvieron los soldados de los presidios en el combate a los insurgentes provenientes de la Nueva Galicia. Se muestra que el esfuerzo de los soldados presidiales tuvo como consecuencia la rebelión de los soldados ópatas en 1820 y la vinculación de los soldados criollos al movimiento independentista encabezado por Agustín de Iturbide. ...

  16. ”The basic human form is female. Maleness is a kind of birth defect”: la discriminación positiva en The Fall

    OpenAIRE

    Carretero, E. (Enrique); Martínez-Lucena, J. (Jorge)

    2016-01-01

    Este artículo intenta hacer un análisis hermenéutico de algunos de los imaginarios sociales puestos en juego en las dos primeras temporadas de la teleserie británica The Fall a través de sus dos personajes protagonistas: la policía Stella Gibson y el asesino en serie Paul Spector. Mientras en el primero de los casos tenemos a una mujer emancipada de algunos roles femeninos anteriores, en el segundo nos encontramos con un sociópata que intenta conciliar su pulsional necesidad de asesinar para ...

  17. Antocianinas em extratos vegetais: aplicação em titulação ácido-base e identificação via cromatografia líquida/espectrometria de massas

    Directory of Open Access Journals (Sweden)

    Wesson Guimarães

    2012-01-01

    Full Text Available Anthocyanins extracted from picao, quaresmeira, petunia, flamboyant, purple ipe, lobeira, pata de vaca, jaboticaba, purple cabbage and jambul were evaluated as natural acid-base indicators. Anthocyanins in extracts were identified using HPLC/MS. Clear, rapid change in color at final-point titration was observed for extracts but only picao showed strong change in pH. Indirect determination of carbonate in limestone using a natural indicator was performed and results compared with phenolphthalein indicator and potentiometer titration. Optimal results were obtained with picao but other extracts showed good accuracy and precision.

  18. Glucose metabolism in rats submitted to skeletal muscle denervation

    Directory of Open Access Journals (Sweden)

    Wilton Marlindo Santana Nunes

    2005-07-01

    Full Text Available This study analyzed the local and systemic effects of immobilization by denervation of the skeletal muscle on glucose metabolism. The rats were submitted to section of the right paw sciatic nerve. A reduction was observed in glucose uptake by the isolated soleus muscle of the denervated paw after 3 and 7 days, but not after 28 days in relation to the control animals. There was no difference after 3 and 7 days in glucose uptake by the soleus muscle of the opposite intact paw in relation to the control. There was increased glucose uptake in the same paw 28 days after denervation. The rate of glucose removal in response to exogenous insulin after 28 days of denervation was significantly higher than in control animals and those observed after 3 and 7 days of denervation. These results suggest that immobilization by denervation interfered not only in glucose metabolism in the skeletal muscle involved but also in other tissues.O estudo analisou os efeitos locais e sistêmicos da imobilização por desnervação do músculo esquelético sobre o metabolismo glicidico. Ratos foram submetidos à secção do nervo ciático da pata direita. Observou-se redução da captação de glicose pelo músculo sóleo isolado da pata desnervada após 3 e 7 mas não após 28 dias em relação a animais controle. Não houve diferença após 3 e 7 dias na captação de glicose pelo músculo sóleo da pata contralateral intacta em relação ao controle. Houve aumento da captação de glicose nesta mesma pata 28 dias após a desnervação. A taxa de remoção da glicose em resposta à insulina exógena após 28 dias de desnervação foi significantemente superior à do controle e àquelas observadas após 3 e 7 dias da desnervação. Esses resultados sugerem que a imobilização por desnervação interfere não só no metabolismo da glicose no músculo esquelético envolvido como também em outros tecidos.

  19. Pensamientos de un violador en serie

    OpenAIRE

    Javier Urrá

    2006-01-01

    El presente artículo corresponde a un estudio de caso, en el que el autor describe material obtenido de trabajar directamente con V.S.R., con el fin de ilustrar los pensamientos de un violador en serie y, a la vez, esclarecer algunos elementos teóricos del psicópata. El documento describe a V.S.R. como un condenado a pena de prisión de 20 años por tres violaciones consumadas, al cumplir 23 años y estando en un centro de reforma, puede reingresar a prisión o bien quedar...

  20. Ejercicio de resistencia y fuerza muscular: diseño de una sesión de fisioterapia cardiovascular hospitalaria

    OpenAIRE

    Marqués Sulé, Elena; Ruescas-Nicolau, Mª Arántzazu

    2012-01-01

    La actividad física es uno de los pilares de la Rehabilitación Cardíaca. La mayoría de estos programas incluyen sesiones de entrenamiento supervisado basadas principalmente en ejercicio aeróbico continuo o interválico, excluyendo el trabajo anaeróbico por el potencial peligro sobre el corazón del cardiópata. Sin embargo, la AACVPR y el ACSM recomiendan el entrenamiento de fuerza en estos casos. Por lo tanto, la prescripción de ejercicio físico debería incluir tanto entrenamiento cardiovascula...

  1. Diseño estructura básica de nave industrial

    OpenAIRE

    ÉLEZ RECHE, DAVID

    2016-01-01

    El presente proyecto tiene por objeto la realización de una nave industrial para una fábrica de muebles de madera. Se pretenden establecer los parámetros estructurales para definir las obras para realizar la construcción de una nave industrial. La actividad que se desarrollará en esta industria forma parte de la industria del mueble de BRICO VALERA, tiene diferentes partes de los muebles tales como traseras para todo tipo de mobiliario de madera, fondos de armarios, patas de me...

  2. A síndrome anserina

    OpenAIRE

    Helfenstein Jr,Milton; Kuromoto, Jorge

    2010-01-01

    Dor no joelho é uma condição comum na clínica diária e a patologia anserina, também conhecida como pata de ganso, tem sido considerada uma das principais causas. O diagnóstico tem sido realizado de maneira eminentemente clínica, o que tem gerado equívocos. Os pacientes queixam-se tipicamente de dor na parte medial do joelho, com sensibilidade na porção ínferomedial. Estudos de imagem têm sido realizados para esclarecer se tais pacientes possuem bursite, tendinite ou ambos os distúrbios na reg...

  3. Sistema de aprendizaje evolutivo para un robot caminante

    OpenAIRE

    Jiménez García, Ángel Luis

    2015-01-01

    Este proyecto consiste en el desarrollo de un sistema de aprendizaje evolutivo para un robot caminante, más concretamente un robot caminante cuadrúpedo con dos grados de libertad en cada pata. Para ello, se utiliza Matlab en sintonía con un software de simulación robótica llamado V-REP (Virtual Robot Experimentation Platform). El robot debe aprender a caminar por sí mismo con secuencias de marcha que produzcan un desplazamiento efectivo de su centro de masa, sin que él tenga conocimiento algu...

  4. Enfoque terapéutico de la dismenorrea desde la medicina tradicional china

    OpenAIRE

    Lozano Monroy, Paola Andrea

    2012-01-01

    La dismenorrea hace referencia un síntoma consistente en dolor pélvico asociado al ciclo menstrual [1, 2, 3]. Desde la medicina alópata, su enfoque terapéutico parte de dos grandes grupos según sea su etiología, Primaria: se presenta principalmente desde la menarquía y corresponde a una causa puramente fisiológica, Secundaria: cuando se han evidenciado anormalidades pélvicas, siendo la endometriosis la principal patología asociada. [1,2] Desde la Medicina Tradicional China, la dismenorrea es ...

  5. Uso medicinal de las plantas por los otomíes del municipio de Nicolás Flores, Hidalgo, México

    OpenAIRE

    A. Sánchez-González; D. Granados-Sánchez; R. Simón-Nabor

    2008-01-01

    El conocimiento de las plantas medicinales por los otomíes (hñähñü) de Nicolás Flores, Hidalgo se ha mantenido a través de las generaciones. La influencia de la medicina alópata está restringida principalmente a la prevención de enfermedades como poliomielitis, sarampión, viruela y paludismo. La medicina tradicional es más viable ante las condiciones socioeconómicas, fisiográficas y culturales en esta región. El objetivo de este estudio fue identificar las especies de plantas que utilizan los...

  6. A Quick Look at SATA Disk Performance

    OpenAIRE

    Barclay, Tom; Chong, Wyman; Gray, Jim

    2004-01-01

    We have been investigating the use of low-cost, commodity components for multi-terabyte SQL Server databases. Dubbed storage bricks, these servers are white box PCs containing the largest ATA drives, value-priced AMD or Intel processors, and inexpensive ECC memory. One issue has been the wiring mess, air flow problems, length restrictions, and connector failures created by seven or more parallel ATA (PATA) ribbon cables and drives in]a tower or 3U rack-mount chassis. Large capacity Serial ATA...

  7. Estudo comparativo da resposta inflamatoria, em ratos, induzida por venenos de serpentes do genero Bothrops em estagios distintos de desenvolvimento

    OpenAIRE

    Susana Elisa Moreno

    1994-01-01

    Resumo: No presente trabalho se estuda a resposta inflamatória induzida por venenos de 3 serpentes de gênero Bothrops (B. jararaca, B. neuwiedi e B. moojeni) em estágios distintos de desenvolvimento, utilizando-se os modelos de peritonite e edema de pata. Os venenos de Bothrops moojeni (VBM), Bothrops jararaca (VBJ), Bothrops neuwiedi (VBN) induzem migração de neutrófilos, de maneira dose-dependente, para a cavidade peritoneal de ratos, com diferentes graus de intensidade, devido, provavelmen...

  8. Estudo comparativo da resposta inflamatoria, em ratos, induzida por venenos de serpentes do genero Bothrops em estagios distintos de desenvolvimento

    OpenAIRE

    Susana Elisa Moreno

    1994-01-01

    No presente trabalho se estuda a resposta inflamatória induzida por venenos de 3 serpentes de gênero Bothrops (B. jararaca, B. neuwiedi e B. moojeni) em estágios distintos de desenvolvimento, utilizando-se os modelos de peritonite e edema de pata. Os venenos de Bothrops moojeni (VBM), Bothrops jararaca (VBJ), Bothrops neuwiedi (VBN) induzem migração de neutrófilos, de maneira dose-dependente, para a cavidade peritoneal de ratos, com diferentes graus de intensidade, devido, provavelmente, a va...

  9. Utilización transnacional de servicios de salud por parte de los migrantes mexicanos en Estados Unidos

    OpenAIRE

    Tonatiuh Tomás González-Vázquez; Cristian Armando Torres-Robles; Blanca Estela Pelcastre-Villafuerte

    2013-01-01

    Objetivo. Documentar la utilización transnacional de re- cursos y servicios de salud de los migrantes mexicanos en Estados Unidos de América (EUA). Material y métodos. Entre diciembre de 2009 y febrero de 2011, a través de entrevistas y grupos focales, se platicó en cuatro estados mexicanos y en California con 135 personas: migrantes de retorno, médicos alópatas y médicos tradicionales. Resul- tados. Ante los obstáculos para acceder al sistema de salud ...

  10. Trasplante cardiaco Cardiac transplant

    OpenAIRE

    Donato Salas-Segura; Mario Sánchez Suen; Carlos Salazar-Vargas

    2008-01-01

    La insuficiencia cardiaca es un cuadro clínico frecuente y de apreciable mortalidad. A menudo de nuestra área de atracción emergen cardiópatas con diferentes grados de discapacidad, dependientes de familiares para su atención y que requieren re-hospitalizaciones y tratamientos costosos y a pesar de ello con mal pronóstico. Las autoridades sanitarias y particularmente el estado invierten anualmente mucho dinero en el tratamiento de los enfermos que la padecen y también en la cobertura de incap...

  11. Trasplante cardiaco

    OpenAIRE

    Donato Salas-Segura; Mario Sánchez Suen; Carlos Salazar-Vargas

    2008-01-01

    La insuficiencia cardiaca es un cuadro clínico frecuente y de apreciable mortalidad. A menudo de nuestra área de atracción emergen cardiópatas con diferentes grados de discapacidad, dependientes de familiares para su atención y que requieren re-hospitalizaciones y tratamientos costosos y a pesar de ello con mal pronóstico. Las autoridades sanitarias y particularmente el estado invierten anualmente mucho dinero en el tratamiento de los enfermos que la padecen y también en la cobertura de incap...

  12. Nutrición en el lactante con cardiopatías congénitas

    OpenAIRE

    Gutiérrez, María Cielo

    2015-01-01

    Las Cardiopatías Congénitas (CC) son las malformaciones congénitas más frecuentes a nivel mundial con una incidencia de 8 a 10 por cada 1000 recién nacidos. En menores de un año, constituyen una de las principales causas de mortalidad infantil. Los lactantes y niños cardiópatas presentan frecuentemente alteraciones en el crecimiento y desarrollo, siendo mayor el compromiso en aquellos pacientes que presenten insuficiencia cardíaca y cianosis. Objetivos: Identificar las representaciones so...

  13. Edema induced by Bothrops asper (Squamata: Viperidae) snake venom and its inhibition by Costa Rican plant extracts

    OpenAIRE

    Badilla, Beatriz; Chaves, Fernando; Mora, Gerardo; Poveda, Luis J.

    2014-01-01

    Se investigó la capacidad de los extractos de las hojas de Urera baccifera, Loasa speciosa, Urtica leptuphylla, Chaptalia nutans, Satureja viminea y de la raíz de Uncaria tomentosa para inhibir el edema inducido por el veneno de Bothrops asper por métodos pletismométricos. Los grupos de ratas fueron inyectados intraperitonealmente con varias dosis de cada extracto y una hora mas tarde se inyectó veneno por vía subcutánea en la pata trasera derecha de la rata. Se evaluó el edema en distintos i...

  14. Clásicos de la Psiquiatría Española del Siglo XIX: Emilio P¡ y Molist.

    Directory of Open Access Journals (Sweden)

    Antonio M Rey González

    1983-01-01

    Full Text Available Evocamos, en esta ocasión, la vida y la obra del ilustre frenópata catalán D. Emilio PI y MOL1ST, figura central, junto con GINE y PARTAGAS, de la psiquiatría española del siglo XIX. Ambos convirtieron a Barcelona en la sede central de la especialidad, que más tarde pasaría a Madrid, aunque sin alcanzar el esplendor logrado en esta etapa de florecimiento catalán

  15. El entrenamiento aeróbico mejora las mediciones ergométricas en enfermos cardiovasculares

    OpenAIRE

    Flores, C; P. Sanz; D. Ansorena

    2010-01-01

    OBJETIVO: estudiar la evolución en el estado de salud cardiovascular de pacientes cardiópatas y/o con factores de riesgo cardiovascular sometidos a un programa supervisado de actividad física aeróbica. MÉTODOS: se seleccionó un total de 56 voluntarios varones de edades entre los 38 y 73 años, con algún tipo de factor de riesgo cardiovascular. Los sujetos fueron clasificados en 4 grupos de acuerdo a sus características: grupo control (personas sin especial patología cardíaca, pero ...

  16. Botulismo tipo C em perus em Minas Gerais, Brasil

    OpenAIRE

    Lobato,Francisco Carlos Faria; Salvarani,Felipe Masiero; Silva,Rodrigo Otávio Silveira; Assis,Ronnie Antunes de; Lago,Luis Alberto do; Carvalho Filho,Maurício Baltazar de; Martins,Nelson Rodrigo da Silva

    2009-01-01

    O botulismo é uma intoxicação causada pela ingestão das toxinas produzidas pelo Clostridium botulinum, que acomete mamíferos e aves e é caracterizado por um quadro de paralisia flácida. Neste trabalho, é descrito um surto de botulismo em perus, ocorrido no município de Santa Luzia, região metropolitana de Belo Horizonte, Minas Gerais. Os animais apresentavam incoordenação motora, paralisia flácida das patas, asas e pescoço. Em um intervalo de 24 horas, todos os 29 animais do plantel vieram a ...

  17. Ejercicio de resistencia y fuerza muscular: diseño de una sesión de fisioterapia cardiovascular hospitalaria

    OpenAIRE

    2012-01-01

    La actividad física es uno de los pilares de la Rehabilitación Cardíaca. La mayoría de estos programas incluyen sesiones de entrenamiento supervisado basadas principalmente en ejercicio aeróbico continuo o interválico, excluyendo el trabajo anaeróbico por el potencial peligro sobre el corazón del cardiópata. Sin embargo, la AACVPR y el ACSM recomiendan el entrenamiento de fuerza en estos casos. Por lo tanto, la prescripción de ejercicio físico debería incluir tanto entrenamiento cardiovascula...

  18. Efeitos do reiki na evolução do granuloma induzido através da inoculação do BCG em hamsters e do tumor ascítico de Ehrlich induzido em camundongos

    OpenAIRE

    2008-01-01

    Estudaram-se os efeitos da influência do Reiki na evolução do granuloma induzido experimentalmente pela inoculação do BCG no coxim plantar de hamsters, assim como os efeitos da mesma terapia em camundongos portadores do tumor ascítico de Ehrlich in vivo e in vitro. No modelo de inflamação granulomatosa crônica, utilizou-se 40 hamsters machos, os quais após serem inoculados com BCG no dia 0 no coxim da pata posterior direita, foram separados em dois grupos contendo 20 animais em cada. Um grupo...

  19. La "Dea Artio" celta y la "Artemis" griega: Un aspecto religioso de la afinidad celto-iliria

    OpenAIRE

    Ruipérez, Martín S.

    2009-01-01

    En una partida de estatuillas romanas de bronce encontradas en 1832 en Muri, en las inmediaciones de Berna (Suiza), se hallaban una figura de osa, una diosa sentada teniendo una patera con frutas, una cesta, un árbol tortuoso y un pedestal con la inscripción Deae Artioni/ Licinia Sabinilla. En seguida se vio que la diosa, el cesto y el árbol tenían su sitio señalado en el pedestal, pero hasta 1899 no se reconstruyó el grupo en su integridad al probar Vionnet que las patas de la osa habían dej...

  20. ESTUDO FITOQUÍMICO DE Bauhinia forficata (FABACEAE)

    OpenAIRE

    Ranggel Carvalho Simões; Sheylla Susan Moreira da Silva de Almeida

    2015-01-01

    O presente trabalho descreve resultados de prospecção fitoquímica preliminar, bioensaio com Artemia salina e atividade antimicrobiana da Bauhinia forficata Link, conhecida popularmente como Pata-de-vaca. O gênero Bauhinia é pantropical, suas espécies são utilizadas em vários tratamentos, como antidiabético, infecções e processos dolorosos. O “screening” fitoquímico foi realizado com o Extrato Bruto Etanóico (EBE) sendo o mesmo obtido a partir da percolação do pó das cascas do caule da B. forf...

  1. Conductas agresivas en la escuela, organización psicológica y vínculación parental

    OpenAIRE

    María Eugenia Villalobos Valencia; Luz Adriana Chaves Villegas; Hosanna Renée Pérez Medina

    2013-01-01

    Este estudio explora la representación de la relación con las figuras parentales que tienen niños escolarizados con conductas agresivas frecuentes y repetitivas. Se aborda desde una perspectiva clínica uti- lizando como instrumentos de evaluación la entrevista clínica y dos pruebas proyectivas: test del dibujo de la familia y test de Pata Negra. Se encontró que las conductas agresivas hacia los otros pueden ser manifestaciones de una organización psicológica que vivencia al otro como una amen...

  2. Conductas agresivas en la escuela, organización psicológica y vínculación parental

    OpenAIRE

    Villalobos Valencia, Maria Eugenia; Chaves Villegas, Luz Adriana; Pérez Medina, Hosanna Renée

    2013-01-01

    Este estudio explora la representación de la relación con las figuras parentales que tienen niños escolarizados con conductas agresivas frecuentes y repetitivas. Se aborda desde una perspectiva clínica utilizando como instrumentos de evaluación la entrevista clínica y dos pruebas proyectivas: test del dibujo de la familia y test de Pata Negra. Se encontró que las conductas agresivas hacia los otros pueden ser manifestaciones de una organización psicológica que vivencia al otro como una amenaz...

  3. Sobre realismo y montaje

    OpenAIRE

    Prada Perez De Azpeitia, Manuel

    2014-01-01

    Se suele pensar que los montajes del arte surgieron a principios del siglo XX de la mano de Picasso, los constructivistas, dadaístas y surrealistas, pero es fácil comprobar la existencia de montajes significativos en distintas épocas y culturas: historias contadas con imágenes yuxtapuestas, seres híbridos compuestos con partes de seres diferentes, objetos con piernas o patas de animal, lo cual permite sospechar que el montaje no es un modo reciente del arte, sino un modo original y universal ...

  4. Influência da radiação por feixe de eletrões no perfil cromatográfico de Bauhinia variegata var candida: flor comestível proveniente do brasil

    OpenAIRE

    Heleno, Sandrina A.; Villavicencio, Anna L.C.H.; Barros, Lillian; Isabel C. F. R. Ferreira

    2016-01-01

    As flores de Bauhinia variegata var candida apresentam coloração branca e são vulgarmente conhecidas como “patas de vaca branca”, sendo muito utilizadas na cozinha gourmet como forma de aumentar a qualidade sensorial e nutricional dos alimentos [1,2]. No presente estudo, as flores foram submetidas a radiação por feixe de eletrões em diferentes doses (0,5 e 0,8 kGy) como forma de descontaminação, e seguidamente analisadas em termos de parâmetros nutricionais (humidade, proteí...

  5. Avaliação da dinâmica conjugal violenta e suas repercusões sobre os filhos

    OpenAIRE

    Santos, Larissa Viana dos; Costa, Liana Fortunato

    2009-01-01

    Este trabalho teve como objetivo geral avaliar como funcionam os subsistemas quando se dá a interação violenta na família, focando a violência no casal. Utilizou-se a Teoria dos Sistemas e a Terapia Familiar para coletar, analisar e discutir os dados, por meio de uma interpretação clínica. Esta é uma pesquisa qualitativa que enfatizou a intensidade e o processo da investigação, por meio de um estudo de caso de uma família, encaminhada pata atendimento pela justiça. Os instrumentos utilizados ...

  6. COMPOSICIÓN QUIMICA DE LA LECHE, DIGESTIBILIDAD in vitro DE LA MATERIA SECA Y PRODUCCIÓN EN VACAS ALIMENTADAS CON GRAMÍNEAS SOLAS O ASOCIADAS CON Lotus uliginosus

    Directory of Open Access Journals (Sweden)

    A. Morales

    2013-01-01

    Full Text Available La presente investigación tuvo como objetivo evaluar el uso de la leguminosa Lotus uliginosus como alternativa de inclusión dentro de las praderas en dos ecorregiones estratégicas de la sabana de Bogotá. en cada finca se evaluaron cuatro tratamientos: 1 kikuyo solo (P. clandestinum, 2 kikuyo asociado con trébol pata de pájaro ( P.clandes-tinum + L. uliginosus, 3 festuca alta sola (F. arundinacea y 4 Festuca alta asociada con trébol pata de pájaro (F. arundinacea + L. uliginosus. el número de bovinos varió de acuerdo a la capacidad de carga de cada finca. se utilizaron animales que se encontraban en el segundo tercio de lactancia durante un período experimental de siete días. en cada tratamiento se determinó la producción (L/día y calidad de leche (% de grasa, proteína y sólidos totales; en la pastura se evaluó la composición química (Ms, Fdn, Fda y la digestibilidad in vitro de la materia seca (divMs. se midió el consumo voluntario. en la finca Megaleche la producción de biomasa presentó diferencias significativas (P<0,05 entre los tratamientos destacándose el tratamiento del kikuyo solo; la calidad nutricional de las pasturas también presentó diferencias (P<0,04 destacándose el tratamiento de kikuyo + trébol pata de pájaro, asociación que también se destacó en consumo voluntario (P< 0.05 y producción de leche (P<0,05. en la finca Colega el contenido de proteína del forraje presentó diferencias cuando las gramíneas se asociaron con el trébol pata de pájaro (P<0,001. se concluyó que la introducción del Lotus en las praderas mejoró la producción de leche y consumo de materia seca en los animales.

  7. [Effects of debagging time and picking off leaf on fruit quality of "Red Fuji" apple].

    Science.gov (United States)

    Zhang, Ji-Xiang; Yue, Yu-Ling; Wei, Qin-Ping; Wang, Xiao-Wei; Zhang, Qiang

    2010-08-01

    This paper studied the effects of debagging time and picking off leaves around fruits on the fruit quality and 1-year old shoots stored nutrition of "Red Fuji" apple. Properly advancing debagging time significantly increased the mean mass, anthocyanin content, and coloration area of the fruits (P picked off, the light environment around the fruits improved significantly (P picked off treatment. Picking off the leaves within 30-45 cm away from the fruits benefited the fruit coloration and anthocyanin accumulation. No significant effects were observed on the 1-year old shoots stored nutrition and their budding in next year among the treatments of picking off leaves. Advancing debagging time and picking off the leaves within 30-45 cm away from the fruits could improve fruit appearance and quality.

  8. The strategy for prevention of measles and rubella prevalence with measles-rubella (MR) vaccine in Japan.

    Science.gov (United States)

    Ihara, Toshiaki

    2009-05-21

    To eliminate the indigenous measles and rubella virus by 2012 in Japan, the strategy fro prevention of measles and rubella prevalence with measles-rubella (MR) vaccine was proposed. Since the vast majority of 1-year old infants are susceptible to measles and rubella, the first MR vaccine, the first MR vaccine should be administered at 1-year old to sustain the herd immunity. Since significant elevation of measles and rubella antibody titers were eliminated in a half of children after the second dose, the second dose of of MR vaccine within 1 year before elementary school entry is the effective maneuver. Moreover, supplement MR vaccination to the teenage group and 20-29 years' group might be necessary, because the mean measles antibody titers in this group were significantly lower compared with those in the older individuals' groups.

  9. Seroepidemiological survey of pathogenic Yersinia in breeding squirrel monkeys in Japan.

    Science.gov (United States)

    Iwata, Taketoshi; Une, Yumi; Lee, Ken-ichi; Nakamura, Shin-ichi; Taniguchi, Takahide; Hayashidani, Hideki

    2010-08-01

    To investigate the prevalence of antibodies to pathogenic Yersinia in breeding squirrel monkeys, the serum samples of 252 squirrel monkeys from 9 zoological gardens in Japan were tested by ELISA using plasmid-encoded Yersinia outer membrane protein (Yops) as the antigen. The cutoff value was calculated by using the serum samples of the squirrel monkeys from Suriname, where no prevalence of pathogenic Yersinia have been reported. According to the cutoff value, 164 of 252 (65.1%) squirrel monkeys were considered positive against pathogenic Yersinia. These positive monkeys belonged to 8 of the 9 zoological gardens, and the percentage of the seropositive monkeys ranged from 22.2 to 89.4%. Furthermore, in one zoological garden, the positive rate of the squirrel monkeys which were over 1 year old (95.7%) was significantly higher than those which were under 1 year old (23.3%). These results suggested that pathogenic Yersinia is highly prevalent among breeding monkeys in Japan.

  10. Lymphedema secondary to filariasis.

    Science.gov (United States)

    Leonard, J C; Humphrey, G B; Basmadjian, G

    1985-03-01

    A 1-year-old immunodeficient boy developed brawny edema of the left foot. Lymphoscintigraphy revealed no evidence of left inguinal activity following pedal injection of Tc-99m-Sn phosphate. Over the next two months, the patient developed lymphedema on the right and repeat scintigraphy demonstrated no movement of isotope from the dorsum of either foot. Subsequent studies identified microfilaria in a nocturnal blood smear, which were thought to represent Brugia beaveri acquired by mosquito transmission in Oklahoma.

  11. Lymphedema secondary to filariasis

    Energy Technology Data Exchange (ETDEWEB)

    Leonard, J.C.; Humphrey, G.B.; Basmadjian, G.

    1985-03-01

    A 1-year-old immunodeficient boy developed brawny edema of the left foot. Lymphoscintigraphy revealed no evidence of left inguinal activity following pedal injection of Tc-99m-Sn phosphate. Over the next two months, the patient developed lymphedema on the right and repeat scintigraphy demonstrated no movement of isotope from the dorsum of either foot. Subsequent studies identified microfilaria in a nocturnal blood smear, which were thought to represent Brugia beaveri acquired by mosquito transmission in Oklahoma.

  12. Biomarkers in the Detection of Prostate Cancer in African Americans

    Science.gov (United States)

    2015-09-01

    establish ELISA and multiplex immunoassays using samples of serum which are less than 1 year old. The ELISA will focus on FABP5. The multiplex immunoassay ...prostate as “suspicious” for prostate cancer and molecular prostate cancer field effects. September 2015 16. Book Chapter in Press Burke HB , Grizzle WE...Burke HB , Grizzle WE. Clinical Validation ofMolecular Biomarkers in Translational Medicine in Biomarkers in Cancer Screening and Early Detection, Sudhir

  13. Corrosive tracheo-esophageal fistula following button battery ingestion.

    Science.gov (United States)

    Harjai, M M; Ramalingam, Wvbs; Chitkara, G; Katiyar, A

    2012-02-01

    We describe a case of corrosive tracheo-esophageal fistula following button battery ingestion in a 1-year old nonverbal pediatric patient. The delay in diagnosis was caused by failure to obtain correct history and failure to detect opacity of the battery in the neck at the first visit. The large fistula was successfully treated with division and repair with non absorbable sutures, with interposition of strap muscles between separated trachea and esophagus.

  14. Macronuclear chromatin structure dynamics in Colpoda inflata (Protista, Ciliophora) resting encystment.

    Science.gov (United States)

    Tiano, L; Chessa, M G; Carrara, S; Tagliafierro, G; Delmonte Corrado, M U

    1999-01-01

    The chromatin structure dynamics of the Colpoda inflata macronucleus have been investigated in relation to its functional condition, concerning chromatin body extrusion regulating activity. Samples of 2- and 25-day-old resting cysts derived from a standard culture, and of 1-year-old resting cysts derived from a senescent culture, were examined by means of histogram analysis performed on acquired optical microscopy images. Three groups of histograms were detected in each sample. Histogram classification, clustering and matching were assessed in order to obtain the mean histogram of each group. Comparative analysis of the mean histogram showed a similarity in the grey level range of 25-day- and 1-year-old cysts, unlike the wider grey level range found in 2-day-old cysts. Moreover, the respective mean histograms of the three cyst samples appeared rather similar in shape. All this implies that macronuclear chromatin structural features of 1-year-old cysts are common to both cyst standard cultures. The evaluation of the acquired images and their respective histograms evidenced a dynamic state of the macronuclear chromatin, appearing differently condensed in relation to the chromatin body extrusion regulating activity of the macronucleus. The coexistence of a chromatin-decondensed macronucleus with a pycnotic extrusion body suggests that chromatin unable to decondense, thus inactive, is extruded. This finding, along with the presence of chromatin structural features common to standard and senescent cyst populations, supports the occurrence of 'rejuvenated' cell lines from 1-year-old encysted senescent cells, a phenomenon which could be a result of accomplished macronuclear renewal.

  15. Lesch-Nyhan Syndrome: a rare disorder of self-mutilating behavior

    Directory of Open Access Journals (Sweden)

    Mrinal Gupta

    2014-01-01

    Full Text Available This paper describes Lesch-Nyhan syndrome in a 1-year-old boy. This X-linked recessive error of purine metabolism presents in infancy with a constellation of mental and developmental retardation, self-mutilating behavior, neurological features and abnormal urine uric acid: creatinine ratio. The basic defect is deficiency in phosphoribosyl transferase production but exact pathomechanism for clinical symptomatology remains un-elucidated. No specific medical treatment is available.

  16. Exploration of nurses' knowledge regarding Ηypertension

    OpenAIRE

    Anastasios Kokkinakis; Dimitrios Michalis; Krystalia Koultoudi; Paraskevi Gourni; Maria Polikandrioti; George Vassilopoulos; Maritsa Gourni

    2012-01-01

    The aim of the present study was to explore nurses' knowledge regarding hypertension. Method and material: The sample –studied consisted of individuals from all levels of nursing personnel. Data were collected by the use the completion of a specially designed questionnaire which apart from demographic variables, it included items concerning knowledge about hypertension. Results: From the 360 participants, 88% were women, while the mean age of the sample-studied was 36,1 years old. In terms of...

  17. Effect of acorn mass and size, and early shoot growth on one-year old container-grown RPM™ oak seedlings

    Science.gov (United States)

    Benjamin C. Grossman; Michael A. Gold; Daniel C. Dey

    2003-01-01

    The purpose of this study was to evaluate the influence of seed source, acorn mass and size, and early shoot growth on morphological traits of 1-year-old oak seedlings. Forested bottomlands in the Midwest have been greatly reduced in the past 150 years as a result of conversion to agriculture and recent catastrophic floods. Due to a lack of available hard mast, intense...

  18. Prolonged breast feeding, diarrhoeal disease, and survival of children in Guinea-Bissau

    DEFF Research Database (Denmark)

    Mølbak, K; Gottschau, A; Aaby, P

    1994-01-01

    was higher in weaned children than in partially breast fed children, both in 1 year olds (relative risk 1.41; 95% confidence interval 1.23 to 1.62) and in 2 year olds (1.67; 1.29 to 2.15). The mean duration of an episode of diarrhoea was 5.3 days in breast fed children compared with 6.3 days in weaned...

  19. Magnetic resonance in diagnosis of ureterocele

    Energy Technology Data Exchange (ETDEWEB)

    Nascimento, Humberto do; Hachul, Mauricio; Macedo Junior, Antonio [Universidade Federal de Sao Paulo (UNIFESP/EPM), SP (Brazil). Div. de Urologia]. E-mail: humbertojr1@aol.com

    2003-05-15

    Ultrasonography is the main non-invasive technique for screening of ureterocele, but presents some difficulties for its diagnosis. Other supplementary diagnostic methods have the disadvantage of being invasive or using ionizing radiation. Magnetic resonance (MR) has a high sensitivity for diagnosing urinary tract malformations in adults and children. We report one case of ureterocele in a 1-year old child with the purpose of presenting its diagnosis through MR. (author)

  20. Emergency anesthesia for evacuating a traumatic acute subdural hemorrhage in a child overdosed with hypertonic saline

    Directory of Open Access Journals (Sweden)

    Chulananda Goonasekera

    2016-01-01

    Full Text Available A previously healthy 1-year-old child with a traumatic acute subdural hemorrhage received 10 times higher dose of hypertonic saline inadvertently immediately before surgery. This case report describes deviations in fluid management needed to alleviate salt toxicity and its adverse effects during surgery under anesthesia perioperatively. The child made an uneventful recovery with no evident residual damage at follow-up.

  1. Outcomes of a Clinic-Based Pediatric Constraint-Induced Movement Therapy Program

    Science.gov (United States)

    Reidy, Teressa Garcia; Naber, Erin; Viguers, Emily; Allison, Kristen; Brady, Kathleen; Carney, Joan; Salorio, Cynthia; Pidcock, Frank

    2012-01-01

    A single-group pre- and post-test design was used to evaluate functional outcomes of a constraint-induced movement therapy (CIMT) protocol implemented in an outpatient therapy center. The participants were 29 children with hemiplegia, ages 1.6-19.1 years old. The less-involved upper limb was placed in a cast that was worn 24 hr a day, 7 days a…

  2. Report on 1Y and 6M child models

    NARCIS (Netherlands)

    Meyer, F.; Deck, C.; Rodarius, C.; Meijer, R.; Yang, J.

    2011-01-01

    This document is the deliverable D.2.3.2 of the CASPER project. It has been done in the framework of WP2 “Child human body modeling” task 2.3 “Develop specific human segments and whole body models per age”. This task aims to provide the meshing of the whole body models of the 1 year old child (1 Y.O

  3. Effects of IBA and Putrescine on Root Formation of Olive Cuttings

    OpenAIRE

    Elham Aslmoshtaghi; Ali Reza Shahsavar; Mohammad Reza Taslimpour

    2014-01-01

    Semi-hardwood cuttings of olive cv. ‘Tokhmkabki’ (low rooting ability) and cv. ‘Roghani’ (high rooting ability) were obtained from 1-year-old shoots. Cuttings were dipped in 2000, 4000, and 6000 mg L-1 IBA, 150 or 300 mg L-1 putrescine and their combination before rooting in greenhouse equipped with an automatic mist system. Rooting ability was evaluated four months after planting for each treatment. Satisfactory rooting occurred when IBA was applied with putrescine, w...

  4. 自閉症エコラリアと健常児の音声模倣における自動性と意図 ―ジャクソニズムの立場からの考察―

    OpenAIRE

    萱村, 俊哉

    2013-01-01

    The significance of the autism echolalia and vocal imitations in 1- year- old normal children is consideredfrom Jacksonistic point of view. In this study, through the observations of the replies or utterances in 1-yearoldnormal children, it was revealed that the automatic vocal imitations frequently existed immediately beforethe appearance of the intentional replies or utterances in them. Such automatic responses were thought toplay a fixed role in language acquisition and development of comm...

  5. The needs and expectations of generation Y nurses in the workplace.

    Science.gov (United States)

    Lavoie-Tremblay, Melanie; Leclerc, Edith; Marchionni, Caroline; Drevniok, Ulrika

    2010-01-01

    Generation Y nurses represent the new nursing workforce. This article describes a study examining the needs, motivations, and expectations of generation Y nurses at the start of their careers. New nurses, on average 24.1 years old in 2007, were interviewed. The generation Y nurses reported that recognition was a key motivator. Their needs are stability, flexible work schedules and shifts, recognition, opportunities for professional development, and adequate supervision.

  6. An Irritable Infant and the Runaway Redback: An Instructive Case

    Directory of Open Access Journals (Sweden)

    Thomas R. Ward

    2011-01-01

    Full Text Available The envenomation syndrome of Redback spider bites, lactrodectism, is distinctive. However diagnosis can be difficult due to an atypical presentation. We describe the case of a 1 year old boy with irritability, diaphoresis and reduced oral intake, in whom a diagnosis was made of redback spider bite. Successful resolution of symptoms was achieved following treatment with antivenom. The symptoms and management of redback spider bites is discussed.

  7. Raine syndrome: expanding the radiological spectrum

    Energy Technology Data Exchange (ETDEWEB)

    Koob, Meriam; Dietemann, Jean-Louis [CHU de Strasbourg Hopital de Hautepierre, Service de Radiologie 2, Strasbourg (France); Doray, Berenice; Fradin, Melanie [CHU de Strasbourg, Hopital de Hautepierre, Laboratoire de Genetique Medicale, Strasbourg (France); Astruc, Dominique [CHU de Strasbourg Hopital de Hautepierre, Service de Neonatologie, Strasbourg (France)

    2011-03-15

    We describe ante- and postnatal imaging of a 1-year-old otherwise healthy girl with Raine syndrome. She presented with neonatal respiratory distress related to a pyriform aperture stenosis, which was diagnosed on CT. Signs of chondrodysplasia punctata, sagittal vertebral clefting and intervertebral disc and renal calcifications were also found on imaging. This new case confirms that Raine syndrome is not always lethal. The overlapping imaging signs with chondrodysplasia punctata and the disseminated calcifications give new insights into its pathophysiology. (orig.)

  8. Report on 1Y and 6M child models

    NARCIS (Netherlands)

    Meyer, F.; Deck, C.; Rodarius, C.; Meijer, R.; Yang, J.

    2011-01-01

    This document is the deliverable D.2.3.2 of the CASPER project. It has been done in the framework of WP2 “Child human body modeling” task 2.3 “Develop specific human segments and whole body models per age”. This task aims to provide the meshing of the whole body models of the 1 year old child (1

  9. Congenital bicuspid aortic valve in an English bulldog.

    Science.gov (United States)

    Visser, Lance C; Scansen, Brian A

    2013-03-01

    A bicuspid aortic valve (BAV) demonstrating moderate valvular stenosis and mild insufficiency was identified in an asymptomatic 1-year-old male cryptorchid English bulldog by transthoracic and transesophageal echocardiography. The BAV was most consistent with type 3 morphology, based upon human classification. Pulmonary valve dysplasia with mild pulmonary stenosis and a suspected persistent left cranial vena cava were also identified. Although BAV is the most common congenital cardiac malformation in humans, it is rare in the dog.

  10. Piracetam-induced changes on the brainstem auditory response in anesthetized juvenile rhesus monkeys (Macaca mulatta). Report of two clinical cases.

    Science.gov (United States)

    Durand-Rivera, A; Gonzalez-Pina, R; Hernandez-Godinez, B; Ibanez-Contreras, A; Bueno-Nava, A; Alfaro-Rodriguez, A

    2012-10-01

    We describe two clinical cases and examine the effects of piracetam on the brainstem auditory response in infantile female rhesus monkeys (Macaca mulatta). We found that the interwave intervals show a greater reduction in a 3-year-old rhesus monkey compared to a 1-year-old rhesus monkey. In this report, we discuss the significance of these observations. © 2012 John Wiley & Sons A/S.

  11. Radiation Dose Assessments for Shore-Based Individuals in Operation Tomodachi

    Science.gov (United States)

    2012-09-30

    Misawa AB Kyoto Kyoto Iwate Morioka City of Ofunato* Osaka Osaka Miyagi Sendai Camp Sendai* Hyogo Kobe Akita Akita Nara Nara Yamagata Yamagata... economy one day per week for the first month (a total of 4 days), the highest doses would have been calculated for a 1-year old child yielding values...Radiation dose estimates to people who were living solely on the local economy near U.S. military installations should be comparable to the values in

  12. Adjuvanted poly(lactic-co-glycolic acid nanoparticle-entrapped inactivated porcine reproductive and respiratory syndrome virus vaccine elicits cross-protective immune response in pigs [Corrigendum

    Directory of Open Access Journals (Sweden)

    Binjawadagi B

    2014-05-01

    Full Text Available Binjawadagi B, Dwivedi V, Manickam C, et al. Int J Nanomedicine. 2014;9:679–694.Note that Figure 1B on page 684 contained an incorrect key. The correct key description should be interchanged, with 2-week-old NP-KAg for open circles, and 1-year-old NP-KAg for closed circles.Read the original article

  13. Clinical Manifestations Vary with Different Age Spectrums in Infants with Kawasaki Disease

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    Hao-Chuan Liu

    2012-01-01

    Full Text Available Background. Kawasaki disease (KD is an acute systemic vasculitis with unknown etiology. The diagnosis of KD depends on clinical manifestations. The prevalence of coronary artery abnormality (CAA is 11.0% and results in cardiac sequelae, such as myocardial infarction or coronary aneurysm, which are the most serious complications in KD. Methods. We divided KD's children into different age groups: ≤6 months old, 7 months to 1 year old, and >1 year old, respectively. Different parameters were compared in each group. Results. Infants ≤6 months old are less likely to fulfill KD's major diagnostic criteria within 10 days, are prone to develop incomplete KD with the lowest cholesterol level, and have the greatest chance to have CAA and the laboratory features associated with CAA, such as the longest time needed to confirm CA diagnosis, lower hemoglobin level, lower albumin level, and higher platelet count. Infants <1 year old develop higher percentage of leukocytosis and sterile pyuria. But this group has fewer patients with neck lymphadenopathy.

  14. The dynamics of reproductive rate, offspring survivorship and growth in the lined seahorse, Hippocampus erectus Perry, 1810

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    Qiang Lin

    2012-02-01

    Seahorses are the vertebrate group with the embryonic development occurring within a special pouch in males. To understand the reproductive efficiency of the lined seahorse, Hippocampus erectus Perry, 1810 under controlled breeding experiments, we investigated the dynamics of reproductive rate, offspring survivorship and growth over births by the same male seahorses. The mean brood size of the 1-year old pairs in the 1st birth was 85.4±56.9 per brood, which was significantly smaller than that in the 6th birth (465.9±136.4 per brood (P<0.001. The offspring survivorship and growth rate increased with the births. The fecundity was positively correlated with the length of brood pouches of males and trunk of females. The fecundity of 1-year old male and 2-year old female pairs was significantly higher than that from 1-year old couples (P<0.001. The brood size (552.7±150.4 of the males who mated with females that were isolated for the gamete-preparation, was larger than those (467.8±141.2 from the long-term pairs (P<0.05. Moreover, the offspring from the isolated females had higher survival and growth rates. Our results showed that the potential reproductive rate of seahorses H. erectus increased with the brood pouch development.

  15. Environmental Equity through Negotiation: A Case Study on Urban Landfills and the Roma Community

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    Ruxandra Mălina Petrescu-Mag

    2016-06-01

    Full Text Available The paper discusses the necessity to bring environmental equity within the Pata Rât Roma community in Northwest Romania, relying on the answers to three questions: “Does environmental equity exist in Pata Rât?”, “How can it be attained?”, and “To what extent can it be brought to the targeted people?” It was shown how a trio of factors tailors the destiny of Roma inhabitants: being a minority, their ethnicity, and the fact they are living on and off what society rejects and dumps—a landfill. The framing of the environmental equity concerns within a vision considering negotiation as the most adequate means to attain it is a novel approach. Further on, the results of the study can fuel win-win solutions in environmental equity. The information abstracted from a set of indicators, assessed through an evaluation matrix, represents a beneficial platform for future bottom-up decisions concerning landfill residents. Three action options were analyzed: on-site living opportunities—that resulted to be preferred, off-site living opportunities, and “Do nothing”. The analysis provides qualitative evidence that the evaluation of environmental equity is largely subjective, because of its complexity and specificity related to geographical, historical, cultural characteristics, and political interests.

  16. A novel gene amplification causes upregulation of the PatAB ABC transporter and fluoroquinolone resistance in Streptococcus pneumoniae.

    Science.gov (United States)

    Baylay, Alison J; Ivens, Alasdair; Piddock, Laura J V

    2015-01-01

    Overexpression of the ABC transporter genes patA and patB confers efflux-mediated fluoroquinolone resistance in Streptococcus pneumoniae and is also linked to pneumococcal stress responses. Although upregulation of patAB has been observed in many laboratory mutants and clinical isolates, the regulatory mechanisms controlling expression of these genes are unknown. In this study, we aimed to identify the cause of high-level constitutive overexpression of patAB in M184, a multidrug-resistant mutant of S. pneumoniae R6. Using a whole-genome transformation and sequencing approach, we identified a novel duplication of a 9.2-kb region of the M184 genome which included the patAB genes. This duplication did not affect growth and was semistable with a low segregation rate. The expression levels of patAB in M184 were much higher than those that could be fully explained by doubling of the gene dosage alone, and inactivation of the first copy of patA had no effect on multidrug resistance. Using a green fluorescent protein reporter system, increased patAB expression was ascribed to transcriptional read-through from a tRNA gene upstream of the second copy of patAB. This is the first report of a large genomic duplication causing antibiotic resistance in S. pneumoniae and also of a genomic duplication causing antibiotic resistance by a promoter switching mechanism.

  17. Estudio del comportamiento térmico y la composición de aceites para el curtido de cueros

    Directory of Open Access Journals (Sweden)

    Grompone, M. A.

    2000-06-01

    Full Text Available The leather industry uses fatty materials to give leather certain characteristics. Neatsfoot oil, a material with variable cost and disponibility, has been used traditionally. Samples of neatsfoot, chicken, fish and rice bran oils are studied in this work. They are evaluated as potential raw materials for leather tanning derivatives, according to their thermal behaviour (Cold Test and DSC and main fatty acids composition (GC. Some seem adequate for that purpose, while others could be modified through thermal fractionation.La industria del cuero utiliza materiales grasos que otorgan determinadas características al cuero. Tradicionalmente se ha usado, entre otros, el aceite de patas de vacuno, producto cuya disponibilidad y costo son muy variables. En este trabajo se estudiaron muestras de distintos aceites de patas de vacuno, de pollo, de pescado y de salvado de arroz. Fueron evaluadas como potenciales materias primas para la obtención de derivados para el curtido de cueros, en función de su comportamiento térmico (“Cold Test” y DSC, y su composición en ácidos grasos principales (GC. Algunos de los aceites estudiados aparecen como adecuados para dicho uso, mientras que otros podrían ser mejorados por fraccionamiento térmico.

  18. Estudo preliminar da atividade antiinflamatória de Bryophillum calycinum Salisb Preliminar study of the anti-inflammatory activity of Bryophillum calycinum Salisb

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    P.J.C. Sousa

    2005-03-01

    Full Text Available Foram avaliados a toxicidade aguda (DL50 do Extrato Bruto Aquoso Liofilizado das folhas de Bryophillum calycinum Salisb. (EBALBc e seu efeito antiinflamatório sobre o edema de pata de rato induzido por carragenina e dextrana. Com a dose de 500 mg/kg (p.o inibiu o edema de pata induzido por dextrana de maneira significativa (p The acute toxicity (LD50 and the anti-inflammatory effect of the crude freeze-dried aqueous extract of the leaves of Bryophillumcalycinum Salisb. (EBALBc was evaluated, on the rat paw edema induced by carrageenin and dextran. The dose of 500 mg/kg (p.o inhibited the paw edema induced by dextran in a significative manner (p < 0.05, ANOVA, Student Newman-Keuls test 60 and 90 minutes, after stimulus while only the oral dose of 1 g/kg of EBALBc inhibited the paw edema induced by carrageenin. The results indicated an anti-edematogenic effect of the extract when tested on the paw edema induced by dextran and carrageenin, suggesting larger specificity of action on the edema induced by dextran. The EBALBc administered orally, in the doses of the 0.1 to 8 g/kg, it did not cause death, making impossible to determine the LD50.

  19. Psicopatía, violencia y criminalidad: un análisis psicológico-forense, psiquiátrico-legal y criminológico (Parte II Psychopathy, violence and crime: a psychological-forensic, psychiatric-legal and criminological analysis (Part II

    Directory of Open Access Journals (Sweden)

    J.M. Pozueco Romero

    2011-12-01

    Full Text Available La Jurisprudencia española se encuentra frecuentemente ante dictámenes periciales en los que aparecen términos como psicópata, trastorno antisocial de la personalidad, personalidad psicopática, psicópata desalmado, psicopatía epileptoide, sociopatía, etc. De esta forma, no es infrecuente que los juristas (magistrados, jueces, fiscales, abogados se hallen desorientados ante tanta terminología que, pese a todo, en absoluto se constituyen en sinónimos. La Doctrina, por su parte, disiente de la visión tradicionalmente ya asentada en la Jurisprudencia de que los psicópatas sean sujetos inimputables. Muchos penalistas conocen bien los textos y estudios psicológicos y psiquiátricos que al respecto existen, y en ellos suelen basarse para establecer ciertas diferencias que aparentemente son sutiles. Una de las controversias más prolongadas es si los términos trastorno antisocial de la personalidad y psicopatía son la misma entidad. En la revisión de esta Parte II también se pretende ahondar en y remarcar esas sutiles diferencias, ya que se ha demostrado reiteradamente que ambas entidades diagnósticas, si bien comparten algunos rasgos en común, no son el mismo concepto ni comportan las mismas consecuencias. Asimismo, se analiza la enconada polémica que existe en torno a la frecuente asociación entre psicopatía y consumo de drogas, una polémica que parece sentar sus orígenes en esa misma confusión terminológica entre psicopatía y trastorno antisocial de la personalidad. Finalmente, se revisa la bibliografía relativa a la criminalidad de los psicópatas, haciendo especial referencia tanto al caso de los delincuentes comunes como al caso de los asesinos en serie y otros delincuentes violentos, sin perder de vista la posición que actualmente tienen los psicópatas a nivel penológico, doctrinal y jurisprudencial.Spanish jurisprudence is frequently faced with the fact that in some expert reports appear terms like psychopath

  20. Efeito analgésico de antagonistas do receptor da histamina H1 em modelo de dor provocada por formalina em ratos Efecto analgésico de antagonistas del receptor de la histamina H1 en un modelo de dolor provocado por formalina en ratones Analgesic effects of H1 receptor antagonists in the rat model of formalin-induced pain

    Directory of Open Access Journals (Sweden)

    Hazem Adel Ashmawi

    2009-08-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Os receptores de histamina mediam vias nociceptivas principalmente no sistema nervoso central. Alguns estudos mostraram efeito analgésico de antagonistas de receptor de histamina no sistema nervoso periférico. Não está claro se o efeito analgésico local é classe específico ou droga específico. MÉTODO: Para responder a essa questão, utilizamos três diferentes antagonistas do receptor H1 (pirilamina, prometazina e cetirizina administrados diretamente na pata do rato, pela via intraperitoneal ou por bloqueio de nervo periférico em modelo de dor induzida por formalina. Observamos o efeito das drogas no comportamento do número de elevações da pata. RESULTADOS: Na fase I, a pirilamina local diminuiu o número de elevações da pata de forma dose-dependente. Na dose mais alta, a diminuição foi de 97,8%. Para a prometazina, a diminuição foi de 92% e para cetizirina, 23,9%. Na fase II, a pirilamina diminuiu o número de elevações da pata em 93,5%, a prometazina em 78,2% e a cetirizina em 80,1%. A administração dos fármacos por via intraperitoneal não alterou o comportamento doloroso. Quando utilizadas para bloqueio de nervo periférico, na fase I, a pirilamina diminuiu o número de elevações da pata em 96,7%, a prometazina em 73,3% e a cetirizina em 23,9%. Na fase II, a pirilamina levou à diminuição de 86,6%, a prometazina de 64,4% e a cetirizina de 19,9%. CONCLUSÕES: Os resultados mostraram que os antagonistas de receptor da histamina H1 apresentam efeitos analgésicos locais, diferentes do efeito sistêmico, sendo um deles anti-inflamatório e classe específico e o outro específico para prometazina e pirilamina, semelhante a efeito clínico anestésico local.JUSTIFICATIVA Y OBJETIVOS: Los receptores de histamina intermedian las vías nociceptivas, principalmente en el sistema nervioso central. Algunos estudios arrojaron un efecto analgésico de antagonistas de receptor de histamina en el

  1. Effect of the activity of the Brazilian polyherbal formulation: Eucalyptus globulus Labill, Peltodon radicans Pohl and Schinus terebinthifolius Radd in inflammatory models

    Directory of Open Access Journals (Sweden)

    Karina C.P. Medeiros

    2007-03-01

    Full Text Available The Brazilian polyherbal formulation (BPF is composed by dyes of Eucalyptus globulus Labill, Peltodon radicans Pohl and Schinus terebinthifolius Raddi in alcohol at 13.3° GL. The formulation is popularly used in Paraíba state, Brazil since 1889 and it is used as an antiseptic and anti-inflammatory medicine. The aim of this study was to evaluate the anti-inflammatory property of the polyherbal formulation. For this purpose it was used the12-O-tetradecanoylphorbol 13-acetate (TPA and capsaicin-induced mouse ear edema and the carrageenan-induced rat paw edema. The BPF at dose of 26 mL/Kg inhibited both 12-O-tetradecanoylphorbol 13-acetate (TPA and capsaicin-induced ear edema by 49% (p O medicamento fitoterápico brasileiro - BPF é composto de corantes das plantas Eucalyptus globulus Labill, Peltodon radicans Pohl e Schinus terebinthifolius Raddi em alcool a 13,3° GL. Este medicamento é popularmente usado no estado da Paraíba, Brasil desde 1889 como anti-séptico e antiinflamatório. O objetivo deste estudo foi avaliar a propriedade antiinflamatória deste medicamento fitoterápico. Para tal, foram utilizadas as técnicas de edema de orelha em camundongos induzido por 12-O-tetradecanoilforbol 13-acetato (TPA ou capsaicina e o edema de pata de rato induzido por carragenina. O BPF na dose de 26 mL/kg inibiu tanto edema de orelha induzido por TPA como por capsaicina a 49% (p < 0.05 e 24% (p < 0.01 respectivamente. Estudos preliminares utilizando a técnica de edema de pata induzido por carragenina demonstraram que a administração oral também inibiu o edema de pata em aproximadamente 29%. Os resultados demonstraram que o medicamento fitoterápico brasileiro (BPF apresentou propriedades antiinflamatórias e a melhor dose foi aquela que é usada pela população.

  2. Potencialização do efeito antiinflamatório e antinociceptivo do diclofenaco e da nimesulida por vitaminas do complexo B

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    L. A. RODRIGUES

    2009-01-01

    Full Text Available

    Investigou-se os efeitos de algumas vitaminas B associadas ao diclofenaco ou nimesulida, na contorção abdominal em camundongos e edema de pata em ratos apenas com a nimesulida ou sua associação com algumas vitaminas B. Verificou-se que o pré-tratamento com as vitaminas tiamina[B1], piridoxina[B6] e cianocobalamina [B12], isoladas ou administradas conjuntamente, não inibiu o edema de pata produzido pela carragenina em ratos, nem as contorções abdominais produzidas pelo ácido acético em camundongos. Por outro lado, a nimesulida [5mg/kg] reduziu o edema de pata em ratos, e a associação das três vitaminas à este fármaco, mas não as vitaminas administradas isoladamente, potencializou seus efeitos nos tempos de duas, três e quatro horas após a carragenina. As contorções abdominais em camundongos foram inibidas pelas doses de 25 ou 50mg/kg de diclofenaco. A associação das três vitaminas ou apenas da cianocobalamina, potencializou as duas doses do diclofenaco utilizadas. As contorções abdominais foram reduzidas também pelo nimesulida [5mg/kg] e a associação das três vitaminas, ou cada uma das vitaminas administradas isoladamente, foram capazes de potencializar os efeitos do nimesulida. É provável que a diferença no mecanismo de ação destes fármacos seja responsável pela diferença dos efeitos das vitaminas. O presente trabalho aponta para a realização de novos estudos com o uso destes antiinflamatórios, combinados com as vitaminas tiamina[B1], piridoxina[B6] e cianocobalamina [B12], em doenças inflamatórias crônicas, na tentativa de reduzir a dose destes fármacos e conseqüentemente diminuindo seus efeitos colaterais. Palavras-chave: diclofenaco; nimesulida; contorção abdominal; edema, cianocobalamina; tiamina.

  3. Efeitos da terapia combinada com ácido zoledrônico e propranolol na resistência mecânica em um modelo de rato com osteoporose por desuso

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    Deepak Kumar Khajuria

    2015-12-01

    Full Text Available Resumo Objetivos: Investigar os efeitos aditivos do agente antirreabsorção ácido zoledrônico (ZOL, isolado e em combinação ao propranolol (PRO, em um modelo de rato com osteoporose por desuso. Métodos: Usou-se um modelo de pata traseira direita de rato privada de descarga de peso para estudar as consequências da falta de descarga de peso sobre o esqueleto durante várias condições, como missões espaciais e repouso prolongado no leito em idosos. Ratos Wistar machos de três meses de idade foram submetidos à imobilização da pata traseira direita (IPTD por 10 semanas para induzir à osteopenia; em seguida, foram divididos aleatoriamente em quatro grupos: 1 – IPTD para controle positivo; 2 – IPTD mais ZOL (50 μg/kg, dose única intravenosa; 3 – IPTD mais PRO (0,1 mg/kg, via subcutânea, cinco dias na semana; 4 – IPTD mais PRO (0,1 mg/kg, via subcutânea, cinco dias na semana mais ZOL (50 μg/kg, dose única intravenosa por outras 10 semanas. Um grupo de ratos não imobilizados foi usado como controle negativo. No fim do tratamento, os fêmures foram removidos e testaram-se a porosidade do osso e suas propriedades mecânicas, além do peso seco e das cinzas do osso. Resultados: No que diz respeito à melhoria da resistência mecânica da diáfise femoral média, a terapia combinada com ZOL mais PRO foi mais eficaz do que a monoterapia com ZOL ou PRO. Além disso, a terapia combinada com ZOL mais PRO foi mais eficaz na melhoria do peso seco do osso e preservou melhor a porosidade do osso cortical do que a monoterapia com ZOL ou PRO em ratos submetidos à imobilização da pata traseira direita. Conclusões: Esses dados sugerem que a terapia combinada com ZOL mais PRO deve ser recomendada para o tratamento da osteoporose por desuso.

  4. 超声在不同时期先天性肌性斜颈患儿中的诊断价值%Value of ultrasonography in diagnosis of children with congenital muscular torticollis in different stages

    Institute of Scientific and Technical Information of China (English)

    王磊; 邱逦; 于雷

    2012-01-01

    目的 探讨超声对不同时期先天性肌性斜颈(CMT)患儿的诊断价值.方法 回顾性分析50例经临床或手术证实为CMT患儿的声像图特点,包括病变区域边界、胸锁乳突肌(SCM)厚度、回声强度及彩色多普勒血流表现,比较﹤1岁患儿和≥1岁患儿超声表现的差异性.结果 50例患儿中,超声诊断CMT患儿46例,诊断准确率92.0%.28例﹤1岁患儿超声表现为患侧SCM局限性增厚,彩色多普勒血流成像(CDFI)示部分病变内部或周边点线状血流信号;18例≥1岁患儿超声表现为患侧SCM厚度多变薄,肌层回声可弥漫性增强或肌层内出现条带状强回声,CDFI未见明显血流信号.两组患儿受累SCM的超声特征比较差异有统计学意义(P﹤0.05).结论 不同时期CMT患儿的二维及彩色多普勒超声表现具有特异性,可指导临床医师选择合适的治疗方式.%Objective To explore the value of ultrasonography in diagnosis of children with congenital muscular torticollis (CMT) in different stages. Methods The sonographic features of 50 patients with CMT proved by the clinical diagnosis and operation were analyzed retrospectively, including the boundary, sternocleidomastoid muscle (SCM) thickness,echo intensity and color Doppler flow imaging of the lesion. The sonographic features of CMT between the children < 1 year old(n=28) and = 1 year old(n=18) were compared. Results Forty-six cases of 50 patients were diagnosed as CMT by ultrasonography, the diagnostic ac-curacy rate was 92.0%. There were significant differences between the children < 1 year old and =1 year old (P < 0.05 ). The ul-trasonographic appearances of the children < 1 year old included local thickening of SCM and point or linear blood flow signals in-side or around the lesions, while those of the children = 1 year old included thinning of the affected SCM, diffusely increased echo signals, or cord-like hyperechoic signals inside the muscle layer and no significant blood flow

  5. Dynamics of testis-ova in a wild population of Japanese pond frogs, Rana nigromaculata.

    Science.gov (United States)

    Kobayashi, Tohru; Kumakura, Masahiko; Yoshie, Sumio; Sugishima, Tomomi; Horie, Yoshifumi

    2015-02-01

    Although many studies have reported the occurrence of testis-ova in wild frog populations, the origin and trigger of testis-ova differentiation/development remain unclear. A high frequency of testis-ova has been previously reported for wild populations of the Japanese pond frog, Rana nigromaculata (cf. Iwasawa and Asai, '59). In the present study, we aimed to clarify the dynamics of testis-ova in this frog species, including the origin and artificial induction of testis-ova. Testis-ova were observed in both mature frogs and puberty-stage frogs (i.e., 0- and 1-year-old frogs). However, the early stages of testis-ova (~pachytene stage) were mostly observed in puberty-stage male frogs at the onset of spermatogenesis. The early stages of testis-ova were observed in the cysts of early secondary spermatogonia and the single cysts of the primary spermatogonium. This finding indicates that testis-ova differentiation occurs during spermatogonial proliferation and that it is correlated with the initiation of spermatogenesis. We also examined whether estrogen exposure induced testis-ova differentiation and how it is correlated with the progression of spermatogenesis. When 1-year-old frogs were exposed to estradiol-17β during spring (i.e., when spermatogenesis was initiated), testis-ova differentiation was induced in a dose-dependent manner. However, this phenomenon did not occur in 1-year-old frogs during summer, (i.e., when the transition from spermatogonia to spermatocytes mainly occurs). These results present the first evidence that testis-ova of the Japanese pond frog are derived from primary and early secondary spermatogonia, and that estrogen exposure induces testis-ova differentiation accompanied by the initiation of spermatogenesis.

  6. [Value of soluble transferrin receptor in the diagnosis of iron deficiency in children].

    Science.gov (United States)

    Wang, Ya-Ping; Shao, Jie; Zhuang, Xue-Ling

    2011-07-01

    To study the prevalence of iron deficiency in children between 6 months and 7 years and to study the diagnostic value of soluble transferrin receptor (sTfR) for iron deficiency in the children. A total of 502 healthy children between 6 months and 7 years from Hangzhou City of Zhejiang Province were enrolled. Serum sTfR, serum ferritin (SF), serum iron (SI), total iron blinding capacity (TIBC), zinc protoporphyrin (ZPP), Hb, MCV and CRP levels were measured. The prevalence rate of iron deficiency was 19.5% in children at ages of 6 months to 7 years. The prevalence rate of iron deficiency was the highest in infants (≤1 year old; 34.7%), followed by in toddlers (1-3 years old; 19.4%) and preschoolers (3-7 years old; 14.0%). The mean serum sTfR level in infants (2.02±0.73 mg/L) was significantly higher than that in toddlers (1.68±0.40 mg/L) and preschoolers (1.67±0.29 mg/L) (Piron deficiency was 2.02 mg/L in infants (sensitivity: 70.3%, specificity: 82.2%). The best cut-off value was 1.85 mg/L in toddlers (sensitivity: 71.7%; specificity: 86.4%), and that was 1.85 mg/L in preschoolers (sensitivity: 77.8%; specificity: 88.6%). Serum sTfR was correlated with SF (r=0.107, PIron deficiency is more prevalent in infants ≤1 year old. The mean serum level and the cut-off value of sTfR in infants are higher than in toddlers and preschoolers. Serum sTfR is an effective index for the diagnosis of iron deficiency in children, especially in infants≤ 1 year old.

  7. Unravelling the importance of forest age stand and forest structure driving microbiological soil properties, enzymatic activities and soil nutrients content in Mediterranean Spanish black pine(Pinus nigra Ar. ssp. salzmannii) Forest.

    Science.gov (United States)

    Lucas-Borja, M E; Hedo, J; Cerdá, A; Candel-Pérez, D; Viñegla, B

    2016-08-15

    This study aimed to investigate the effects that stand age and forest structure have on microbiological soil properties, enzymatic activities and nutrient content. Thirty forest compartments were randomly selected at the Palancares y Agregados managed forest area (Spain), supporting forest stands of five ages; from 100 to 80years old to compartments with trees that were 19-1years old. Forest area ranging from 80 to 120years old and without forest intervention was selected as the control. We measured different soil enzymatic activities, soil respiration and nutrient content (P, K, Na, Mg, Cr, Mn, Fe, Co, Ni, Cu, Zn, Pb and Ca) in the top cm of 10 mineral soils in each compartment. Results showed that the lowest forest stand age and the forest structure created by management presented lower values of organic matter, soil moisture, water holding capacity and litterfall and higher values of C/N ratio in comparison with the highest forest stand age and the related forest structure, which generated differences in soil respiration and soil enzyme activities. The forest structure created by no forest management (control plot) presented the highest enzymatic activities, soil respiration, NH4(+) and NO3(-). Results did not show a clear trend in nutrient content comparing all the experimental areas. Finally, the multivariate PCA analysis clearly clustered three differentiated groups: Control plot; from 100 to 40years old and from 39 to 1year old. Our results suggest that the control plot has better soil quality and that extreme forest stand ages (100-80 and 19-1years old) and the associated forest structure generates differences in soil parameters but not in soil nutrient content. Copyright © 2016 Elsevier B.V. All rights reserved.

  8. Órdenes de no reanimar y cuidados paliativos en pacientes fallecidos en un servicio de cardiología : ¿Qué podemos mejorar?

    OpenAIRE

    Martínez Sellés Oliveria Soares, Manuel

    2010-01-01

    Con el objetivo de evaluar el uso de órdenes de no reanimar y de cuidados paliativos en cardiópatas, registramos 198 muertes consecutivas en nuestro servicio. En 113 (57%) se decidió no reanimar, se reflejó en la historia clínica en 102 (90,3%) y en 74 (65,5%) en las hojas de enfermería. Se informó a 5 pacientes (4,4%) y a 95 familias (84,1%). El uso de medidas paliativas fue escaso en pacientes no reanimables, 56 (49,6%) recibieron cloruro mórfico y 5 (4,4%), asistencia espiritual. Sin embar...

  9. Efeitos do ultra-som terapêutico na prevenção de aderências tendinosas

    OpenAIRE

    Rosângela Lobato

    2002-01-01

    O trabalho realizado estudou experimentalmente os efeitos do ultra-som terapêutico na prevenção de aderências tendinosas e no reparo tendíneo. Foi selecionado para o estudo o tendão flexor profundo do 3º dedo na transição das zonas 3 e 4 da pata dianteira direita de coelho. Foram utilizados 30 coelhos fêmeas adultas jovens, com peso corporal médio de 2,7 Kg, divididos em 3 grupos (A, B e C) de 10 animais, sob anestesia para a produção da lesão no tendão, feita por escarificação com o uso do b...

  10. Propriedades farmacológicas do extrato etanólico de Eremanthus erythropappus (DC. McLeisch (Asteraceae Pharmacological properties of the ethanol extract from Eremanthus erythropappus (DC. McLeisch (Asteraceae

    Directory of Open Access Journals (Sweden)

    Marcelo S. Silvério

    2008-09-01

    Full Text Available O presente trabalho investigou as propriedades antinociceptiva, antiinflamatória e antiulcerogênica do extrato etanólico dos galhos de E. erythropappus. Foram realizados os testes de contorções abdominais induzidas por ácido acético; tempo da lambida da pata induzida por formalina; placa quente; edema de pata induzido por carragenina; lesões ulcerativas induzidas por indometacina e etanol. As doses de 50, 100 e 200 mg/kg inibiram as contorções em 43,07%, 69,34% e 70,07%, respectivamente. O tempo da lambida da pata foi reduzido em ambas as fases nas doses testadas, enquanto o tempo de latência da placa quente teve efeito significativo na dose de 200 mg/kg. O edema de pata foi reduzido em 23,81% (100 mg/kg e 47,62% (200 mg/kg. O índice ulcerativo das lesões induzidas por indometacina foi reduzido na dose de 100 mg/kg e 200 mg/kg, enquanto a dose de 200 mg/kg teve efeito significativo sobre o volume e o pH do suco gástrico. O índice ulcerativo e o volume do suco gástrico, induzidos por etanol, foram reduzidos na dose de 200 mg/kg, enquanto o pH do suco gástrico aumentou nas doses de 100 e 200 mg/kg. Os resultados indicam que o extrato etanólico de E. erythropappus avaliado pode constituir alvo potencial para uso em terapias da dor, da inflamação e de úlcera.The present work investigated the antinociceptive, anti-inflammatory and antiulcerogenic activities of Eremanthus erythropappus ethanol extract. The tests were carried out by acetic acid writhing, paw licking induced by formalin, hot plate, indomethacin- and ethanol-induced ulcer. The doses of 50, 100 and 200 mg/kg inhibited the contortions in 43.07, 69.34 and 70.07%, respectively. Both phases of paw lick were reduced at the tested doses, while reaction time at hot plate had significant effect at 200 mg/kg. The paw edema was decreased in 23.81% (100 mg/kg and 47.62% (200 mg/kg. The index of ulceration induced by indomethacin was reduced at the doses of 100 and 200 mg

  11. La globalización y su impacto en la economía de la educación en el sistema educativo público de Puerto Rico

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    Pizarro Figueroa, J.

    2010-01-01

    Full Text Available En este mundo globalizado la educación se constituye en un factor indispensable pata el crecimiento del ser humano y su sociedad. La educación es determinante para el crecimiento económico, social y ecológico de un país. En este ensayo presentamos un análisis sobre la economía de la educación. A tales fines, comenzaremos discutiendo el concepto de la globalización y sus características, tanto sus ventajas como desventajas. Posteriormente, analizaremos la economía de la educación en el Sistema Educativo Público del Estado Libre Asociado de Puerto Rico (territorio no incorporado de los Estados Unidos de América. Cómo la economía incide en la educación y viceversa. Finalmente, presentaremos las conclusiones producto de este ensayo.

  12. Crítica de Libros.

    Directory of Open Access Journals (Sweden)

    Fernando Colina Pérez

    1981-01-01

    Full Text Available

    PRESENTACION y ENSEÑANZAS DE SCHREBER, Daniel Paul Schreber -«Memorias de un Neurópata» -Ediciones Petrel. Buenos Aires -1978

    LA TEORIA COMO FICCION, Maud Mannoni -Editorial Crítica -1980

    MAS ALLA DE LA SOCIOLOGIA: EL GRUPO DE DISCUSION: TEORIA y CRITICA, Jesús Ibáñez -Ed. Siglo XXI -Madrid, 1979.

    LA SEXUALIDAD -Jean Laplanche

    EL ORDEN PSIQUIATRICO -Robert Castel -Ediciones La Piqueta. Madrid, 1980 -Colección «La Genealogía del Poder», dirigida por Julia Varela y Fernando Alvarez Uría

  13. Productividad secundaria en los esteros de la barra de arena El Mogote en la Ensenada de La Paz, Baja California Sur, México Secondary productivity in the estuaries of El Mogote sand bar in Ensenada de La Paz, Baja California Sur, Mexico

    Directory of Open Access Journals (Sweden)

    Jorge A. López-Rocha

    2012-04-01

    Full Text Available Los ecosistemas de manglar son un hábitat crítico para numerosas especies y su productividad es importante por su contribución de detritos orgánicos y su producción secundaria. El objetivo del trabajo fue definir indicadores de productividad secundaria para establecer una línea base que permita medir alteraciones en el sistema de manglar por posibles perturbaciones naturales o antropogénicas. Como indicadores se escogieron los moluscos bivalvos pata de mula, Anadara tuberculosa y el ostión de mangle, Crassostrea palmula. Se realizaron muestreos en tres esteros de agosto de 2007 a julio de 2009. Se estimó la abundancia y la producción secundaria con base en el incremento de biomasa. Para la estimación del incremento en peso se usaron las tasas de crecimiento individual obtenidas mediante un análisis de distribuciones de frecuencia de tallas. La abundancia promedio fue de 1.27 y 510 ind · m-2 de la pata de mula y ostión de mangle respectivamente. Se estimó una tasa de crecimiento de 4.91 mm · mes-1 (3.67 g · mes-1 para la pata de mula y de 3.80 mm · mes-1 (0.18 g · mes-1 para el ostión de mangle. La producción secundaria promedio de pata de mula fue de 4.51 g · m-2 · mes-1 y fue mayor durante la primavera, mientras que para el ostión de mangle fue de 97.9 g · m-2 · mes-1, registrándose la máxima producción durante el verano. Los resultados obtenidos demuestran que estos indicadores de calidad del bentos son adecuados para medir alteraciones al sistema de manglar de la Ensenada de La Paz, B. C. S., México.Mangrove ecosystems are critical habitats for many species, and their productivity is important because of their contribution of organic detritus and secondary production. The objective of this study was to identify suitable indicators of secondary productivity of mangrove systems, in order to establish a baseline for measuring changes in the mangrove system due to natural or anthropogenic potential disturbances. The

  14. Random matrix models of stochastic integral type for free infinitely divisible distributions

    CERN Document Server

    Molina, J Armando Domínguez

    2010-01-01

    The Bercovici-Pata bijection maps the set of classical infinitely divisible distributions to the set of free infinitely divisible distributions. The purpose of this work is to study random matrix models for free infinitely divisible distributions under this bijection. First, we find a specific form of the polar decomposition for the L\\'{e}vy measures of the random matrix models considered in Benaych-Georges who introduced the models through their measures. Second, random matrix models for free infinitely divisible distributions are built consisting of infinitely divisible matrix stochastic integrals whenever their corresponding classical infinitely divisible distributions admit stochastic integral representations. These random matrix models are realizations of random matrices given by stochastic integrals with respect to matrix-valued L\\'{e}vy processes. Examples of these random matrix models for several classes of free infinitely divisible distributions are given. In particular, it is shown that any free sel...

  15. ‘COROJO 2006’: NUEVA VARIEDAD CUBANA DE TABACO NEGRO (Nicotiana tabacum L.

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    Vivaldo García Morejón

    2013-01-01

    Full Text Available En la Estación Experimental del Tabaco, de San Juan y Martínez, Pinar del Río durante la campaña tabacalera 2001-2002, se realizó un cruzamiento sexual con el objetivo de obtener una variedad de tabaco negro con mayor rendimiento que la comercial ‘Criollo 98’, resistente al moho azul ( Peronospora hyocyami de Bary, a la pata prieta ( Phytophthora parasitica Dast. var . Nicotianae Breda de Haan, al virus del mosaico del tabaco (VMT y a la necrosis ambiental. Después de cinco generaciones de autofecundación y selección por el método genealógico se obtuvieron siete variedades resistentes. El cruce originó la nueva variedad `Corojo 2006 ́ que superó a la `Criollo 98 ́.

  16. The structure of the cyanobactin domain of unknown function from PatG in the patellamide gene cluster.

    Science.gov (United States)

    Mann, Greg; Koehnke, Jesko; Bent, Andrew F; Graham, Rachael; Houssen, Wael; Jaspars, Marcel; Schwarz-Linek, Uli; Naismith, James H

    2014-12-01

    Patellamides are members of the cyanobactin family of ribosomally synthesized and post-translationally modified cyclic peptide natural products, many of which, including some patellamides, are biologically active. A detailed mechanistic understanding of the biosynthetic pathway would enable the construction of a biotechnological `toolkit' to make novel analogues of patellamides that are not found in nature. All but two of the protein domains involved in patellamide biosynthesis have been characterized. The two domains of unknown function (DUFs) are homologous to each other and are found at the C-termini of the multi-domain proteins PatA and PatG. The domain sequence is found in all cyanobactin-biosynthetic pathways characterized to date, implying a functional role in cyanobactin biosynthesis. Here, the crystal structure of the PatG DUF domain is reported and its binding interactions with plausible substrates are investigated.

  17. The structure of the cyanobactin domain of unknown function from PatG in the patellamide gene cluster

    Science.gov (United States)

    Mann, Greg; Koehnke, Jesko; Bent, Andrew F.; Graham, Rachael; Houssen, Wael; Jaspars, Marcel; Schwarz-Linek, Uli; Naismith, James H.

    2014-01-01

    Patellamides are members of the cyanobactin family of ribosomally synthesized and post-translationally modified cyclic peptide natural products, many of which, including some patellamides, are biologically active. A detailed mechanistic understanding of the biosynthetic pathway would enable the construction of a biotechnological ‘toolkit’ to make novel analogues of patellamides that are not found in nature. All but two of the protein domains involved in patellamide biosynthesis have been characterized. The two domains of unknown function (DUFs) are homologous to each other and are found at the C-termini of the multi-domain proteins PatA and PatG. The domain sequence is found in all cyanobactin-biosynthetic pathways characterized to date, implying a functional role in cyanobactin biosynthesis. Here, the crystal structure of the PatG DUF domain is reported and its binding interactions with plausible substrates are investigated. PMID:25484206

  18. Cardiopatías y embarazo

    Directory of Open Access Journals (Sweden)

    Francisco de Jesús Valladares Carvajal

    2011-01-01

    Full Text Available La cardiopatía es la causa más frecuente de muerte materna indirecta en el mundo. Es decir, la presencia de enfermedad cardíaca no excluye el embarazo, pero aumenta el riesgo para la madre y para el feto y requiere de un tratamiento especial. Los cambios hemodinámicos propios del embarazo pueden hacer sospechar la presencia de enfermedad cardíaca, por lo que es importante conocer los síntomas y signos indicadores de cardiopatía estructural en la mujer embarazada. La morbimortalidad materna dependerá del tipo de cardiopatía y de la capacidad funcional en el momento de la concepción. De otro lado las gestaciones en madres cardiópatas se han asociado también a mayor incidencia de problemas para el feto, y por tanto, de un aumento de la mortalidad perinatal.

  19. Modulação da nocicepção em camundongos por receptores ETb para endotelinas

    OpenAIRE

    Fernandes, Marcília Baticy Monteiro Morais

    2006-01-01

    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Farmacologia. O presente estudo investigou a importância de receptores ETB para endotelinas na modulação da resposta de camundongos à aplicação de estímulos nociceptivos químico e térmico e mecânico não nociceptivo na pata traseira. A administração intraplantar de sarafotoxina S6c, um agonista seletivo de receptores ETB, causou hiperalgesia à formalina e à capsaicina...

  20. A new Lepeophtheirus (Copepoda: Siphonostomatoida: Caligidae from Isla del Coco National Park, Costa Rica, Eastern Tropical Pacific

    Directory of Open Access Journals (Sweden)

    Eduardo Suárez-Morales

    2012-11-01

    copépodo calígido del género Lepeophtheirus con base en especímenes femeninos recolectados a partir de muestras de plancton en aguas de Bahía Wafer, isla del Coco, una isla oceánica del Pacífico Tropical Oriental. La nueva especie, L. alvaroi sp. nov., tiene algunas afinidades con congéneres que poseen un abdomen relativamente corto, un complejo genital más ancho que largo y un exópodo de la pata 4 con 3 segmentos. Esta especie difiere de la mayoría de estas especies por la presencia de un proceso maxilular no ramificado y por el tamaño relativo de las garras terminales de la pata 4, con dos elementos igualmente largos. Está más cercanamente relacionada con otras dos especies del Pacífico Oriental: L. dissimulatus Wilson, 1905 y L. clarionensis Shiino, 1959. Difiere de estas especies por las proporciones y forma del complejo genital, la forma de la furca esternal, la longitud relativa de los segmentos maxilares, la ausencia de un proceso pectiniforme en el segmento maxilar distal, la longitud de la pata 4 y la armadura de la pata 5. La nueva especie representa el primer Lepeophtheirus descrito en aguas del Pacífico de Costa Rica. La baja diversidad del género en esta región tropical se explica por su tendencia a preferir hospederos de latitudes templadas. Hasta encontrar más evidencia, el hospedero de esta especie de Lepeophtheirus permanece desconocida.

  1. Baja Andesia: sed y poéticas tramontinas. Un desvío etnográfico a mano alzada

    OpenAIRE

    Pedro Araya

    2012-01-01

    Si yo fuese dromedario no tendría sed. ¿Qué hora es ?Vicente Huidobro1.El antropólogo-poeta-ponencista despierta luego de un sueño intranquilo. Tiene sed. Algo recuerda. Un escozor, dice, un poco antes, en la misma, como de ron, como de vino y el fumadero de las caras ; como si, apenas, algo de lo exagerado de una opinión, entre una cosa y la otra, hubiera olvidado. Sabe que debe hablar aquella misma mañana. Sabe. La pata de los caballos, piensa. La tribu estará reunida. No la suya. No se sus...

  2. Baja Andesia: sed y poéticas tramontinas. Un desvío etnográfico a mano alzada

    Directory of Open Access Journals (Sweden)

    Pedro Araya

    2007-07-01

    Full Text Available Si yo fuese dromedario no tendría sed. ¿Qué hora es ?Vicente Huidobro1.El antropólogo-poeta-ponencista despierta luego de un sueño intranquilo. Tiene sed. Algo recuerda. Un escozor, dice, un poco antes, en la misma, como de ron, como de vino y el fumadero de las caras ; como si, apenas, algo de lo exagerado de una opinión, entre una cosa y la otra, hubiera olvidado. Sabe que debe hablar aquella misma mañana. Sabe. La pata de los caballos, piensa. La tribu estará reunida. No la suya. No se sus...

  3. De escarabajos y otros bichos: intimidades del paciente mental en los laberintos del capitalismo biomédico

    Directory of Open Access Journals (Sweden)

    María Angélica Ospina Martínez

    2011-09-01

    Full Text Available El mercado global farmacéutico ha provocado en la actualidad una actitud distinta frente a la enfermedad. Médicos, enfermeros y terapeutas alópatas son hoy “ofertantes”, mientras sus pacientes se han convertido en “usuarios”, consumidores de bienes y servicios para aliviar su sufrimiento. El tratamiento de la enfermedad mental en el medio hospitalario no escapa de esta lógica mercantil de la biomedicina. A través de un relato etnográfico y de las narrativas de algunos pacientes institucionalizados, el artículo aborda algunas expresiones íntimas de la experiencia de la locura en el marco del capitalismo biomédico en Bogotá, Colombia.

  4. Beklemishevia hispaniola n. sp., nuevo representante de la Cohorte Palaeosomata (Acari, Oribatei en España

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    Pérez-Iñigo, C.

    1996-12-01

    Full Text Available A new species of oribatid mite (Acari, Oribatei belonging to the family Ctenacaridae (Cohors Palaeosomata is described; this species was recorded several times in Spain as Beklemishevia galeodula Zachvatkin, 1945. The new species is easily distinguishable from the mentioned one because of the presence of three claws in every leg, a noticeable pigidial neotrichy and the absence of short, almost spiniform, setae on the pygidium.Se describe una nueva especie de oribátido (Acari, Oribatei perteneciente a la familia Ctenacaridae (Cohorte Palaeosomata que habia sido citada varias veces en España como Beklemishevia galeodula Zachvatkin, 1945, y de la que se diferencia por presentar tres uñas en todas las patas, una acentuada neotriquia pigidial y carecer de setas cortas espiniformes en el pigidio.

  5. Contribuição ao conhecimento da morfologia de Oxyagrion Terminale Selys, 1876 com um estudo sobre a genitália externa (Odonata, Zygoptera, Coenagrionidae

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    Jane Margaret Costa

    1984-09-01

    Full Text Available Foi feita uma análise minuciosa da morfologia externa de Oxyagrion terminale Selys, 1876, onde foram interpretadas as principais estruturas da cabeça, tórax, patas, asas e abdômen vistos de vários ângulos, dando especial atenção ao estudo da genitália de ambos os sexos, em microscopia ótica e eletrônica de varredura.A full description of the external morphology of Oxyagrion terminale Selys, 1876, was made through optical microscopy and scanning electron microscopy. The main structures of the head, torax, legs, wings and abdomen, were studied with specieal attention to the genital structures of both sexes.

  6. Avaliação do efeito antiparasitário do omeprazol na prevenção do desenvolvimento de lesões cutâneas em hamsters infectados por Leishmania brasiliensis Evaluation of omeprazole's antiparasitary effect preventing the development of cutaneous lesions due to Leishmania brasiliensis in hamsters

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    Hélio Amante Miot

    2005-12-01

    Full Text Available FUNDAMENTOS: A leishmaniose tegumentar americana permanece doença endêmica em diversas regiões brasileiras. A sobrevivência do parasita no interior dos macrófagos se deve, em parte, pela atividade de uma K+/H+-ATPase de membrana que pode ser inibida pelo omeprazol. OBJETIVOS: Avaliar a eficácia do omeprazol na prevenção do desenvolvimento de lesões de leishmaniose em hamsters. MÉTODOS: Empregaram-se 18 hamsters, divididos em três grupos: o grupo L recebeu apenas a inoculação de L. brasiliensis na pata anterior direita, o grupo O recebeu apenas doses diárias de 0,4mg de omeprazol subcutâneo, e o grupo L+O recebeu o inóculo de leishmanias e o tratamento com omeprazol desde o dia da inoculação. O estudo foi conduzido por 42 dias, realizaram-se medidas dos diâmetros das patas semanalmente, e, ao final do estudo, foram realizados esfregaços das lesões para verificação dos parasitas. RESULTADOS: Os hamsters dos grupos L e L+O desenvolveram lesões de leishmaniose tegumentar havendo ulceração em duas patas do grupo L e uma do grupo L+O. Ao final do estudo, a mobilidade e vitalidade no grupo L foram menores que em L+O, e estas menores que no grupo O. Os diâmetros das patas inoculadas nos grupos L e L+O foram significativamente maiores que no início do estudo (pBACKGROUND: Cutaneous leishmaniasis remains an endemic disease in several brazilian regions. The parasite’ survival in macrophages is due to a membrane K+/H+-ATPase that can be inhibited by omeprazole. OBJECTIVES: Evaluate omeprazole’s efficacy preventing the development of cutaneous leishmaniasis in hamsters. METHODS: Eighteen hamsters were divided in 3 groups: the L group received an inoculation of L. brasiliensis on right paw, the O group received daily 0,4mg omeprazole subcutaneously, and L+O group received both omeprazole and the inocule. The study was performed in 42 days, and the measurements of the diameter of paws were done weekly. At the end of the study

  7. Transmissão de produtos farmacêuticos tópicos através de energia ultra-sônica na regeneração de lesões da musculatura esquelética - enfoque morfológico

    OpenAIRE

    Morsoleto, Maria José Misael da Silva

    2003-01-01

    Este trabalho apresenta uma série de resultados referentes à utilização da transmissão de fármacos tópicos através de ondas ultra-sônicas (fonoforese), em lesão cirúrgica produzida no músculo tibial anterior de ratos Wisttar. O fármaco utilizado foi a hidrocortisona gel manipulada a 10%. Foram utilizados 42 ratos Wisttar machos, com 60 dias de idade e peso médio de 300,0 g ( 50,0 g), que foram submetidos à lesão cirúrgica na pata direita no músculo tibial anterior. Após 24 horas a área da les...

  8. Luces y sombras en la historia de los grupos indígenas en Sonora, siglos XIX-XXI. Panorama historiográfico

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    Zulema Trejo Contreras

    2015-01-01

    Full Text Available en este artículo se presenta un análisis panorámico respecto a la historiografía de los grupos indígenas mayo, yaqui y ópata; el objetivo es conocer cómo ha evolucionado la forma en que se les ha estudiado. Se destaca la concepción dualista de los autores respecto a las etnias, la inserción de los textos revisados en el contexto historiográfico nacional y la manera como han ido cambiando los temas de estudio en relación con la historia de los grupos indígenas de Sonora.

  9. Recomendaciones terapéuticas en la insuficiencia cardíaca Therapeutic recommendations in heart failure

    Directory of Open Access Journals (Sweden)

    Annery Luis Martínez

    2003-12-01

    Full Text Available Se presentan algunas recomendaciones terapéuticas para el tratamiento de la insuficiencia cardíaca (IC. Esta se ha convertido en un creciente problema de salud, debido al envejecimiento poblacional y al aumento de la supervivencia de las pacientes cardiópatas. Las opciones terapéuticas que se aconsejan están encaminadas a lograr una mejor calidad de vida del paciente, para lo cual es vital el entendimiento de los procesos fisiopatológicos de esta enfermedad.Some therapeutic recommendations for the treatment of heart failure are made. It has become an increasing health problem due to the population aging and to the rise of survival among cardiopathic patients. The recommended therapeutic options are directed to attain a better quality of life of the patients, for which the comprehension of the physiopathological processes of this disease is vital.

  10. La radio en la difusión universitaria. A la búsqueda de sentido

    Directory of Open Access Journals (Sweden)

    Lourdes de Quevedo Orozco

    2004-01-01

    Full Text Available Un panorama ideal de la radio universitaria en México sería contar con un amplio número de emisoras en el cuadrante, semejante al conjunto de los centros educativos profesionales del país. Ésta es la imagen del mundo al revés, como bien dice el escritor Eduardo Galeano en Patas arriba. Un mundo que nos enseña a padecer la realidad en lugar de cambiarla, a olvidar el pasado en lugar de escucharlo y a aceptar el futuro en lugar de imaginarlo. Este artículo presta oídos a algunas voces del pasado, con el fin de encontrar sentido a la situación presente de la radiodifusión universitaria. Lanza al aire algunas ideas para participar en la creación de un posible futuro hertziano.

  11. Solid and aqueous mercury in remote river sediments (Litany River, French Guyana, South America)

    Science.gov (United States)

    Charlet, L.; Roman-Ross, G.; Spadini, L.; Rumbach, G.

    2003-05-01

    Mercury content in river sediments was investigated, in the Haut Maroni river basin (French Guyana, South America), around Antecume-Pata, a village where Wayanas Amerindians are contaminated with mercury. Solid sediment particulate total mercury content indicate a 100 to 150 ng/g Hg geochemical background level. Sediments act as an environmental archive: gold mining contaminated sediments have up to 400 ng/g total mercury. Pore waters from contaminated sediments are enriched in Fe(II) and Hg(II) by a factor 40 compared to uncontaminated sediment pore waters, due to more acute anoxie conditions. They act therefore as a major source of dissolved mercury in remote tropical aquatic ecosystems. Keywords: Mercury, sediment, DGT and DET techniques, pore water, gold mining.

  12. El Sulfato de Magnesio prepinzamiento aórtico como preservador energético en cirugía cardíaca

    OpenAIRE

    Santos Gracia, José Juan

    2003-01-01

    Hay evidencia de un déficit crónico de magnesio en la población mundial atribuido a ingestión deficitaria. En los cardiópatas, la utilización de drogas depletoras agrava este déficit y contribuye a la aparición de arritmias malignas. El magnesio ha sido recomendado en el tratamiento del Infarto Agudo del Miocardio por preservar la energía de la célula cardíaca isquémica o reperfundida desde la era “pretrombolítica” y en todas las variantes de arritmias. Sin embargo, su utilización en cardioci...

  13. Prevalencia de infección por vih en pacientes con patología dermatológica en un centro de referencia nacional

    OpenAIRE

    Tamayo-Buendía, Margarita; Sánchez-Vanegas, Guillermo; Porras de Quintana, Luisa

    2013-01-01

    Objetivo Estimar la prevalencia de  infección por VIH en pacientes con patología cutánea en un centro de referencia nacional en Colombia.Métodos Se realizó un estudio de corte transversal, en pacientes dermópatas mayores de 18 años, sin diagnóstico previo de infección por VIH. Se calculó un tamaño muestral de 1 537 pacientes. Se definió como caso confirmado un paciente con pruebas positivas de Elisa y Western Blott. La prevalencia se calculó como el número de casos confirmados sobre el total ...

  14. Assessing locomotion deficiency in broiler chicken Medida de deficiência locomotora em frango de corte

    Directory of Open Access Journals (Sweden)

    Irenilza de Alencar Nääs

    2010-04-01

    Full Text Available Locomotion deficiencies in broiler production cause poor welfare and lead to change in drinking and feeding behavior with consequent loss in weight gain. This research aimed to assess locomotion deficiencies in broiler chicken by analyzing the vertical peak force on both feet during walk. A chamber was built with an inlet ramp, a horizontal walkway in the middle and an outlet ramp. In the walkway a thin mat with piezoelectric crystal sensors was placed to record the step vertical peak force of the feet while walking on the force platform. The measurement system consisted of a mat with electronic sensors and software that allowed real time recording of the forces and the processing and analysis of data. Footage was taken from two digital video cameras and used for gait scoring. Forty male broilers were chosen at random, grown under similar rearing conditions and farms, with age varying from 49 to 28 days (ten birds of same age to be used in the trial. Measurement consisted of inducing the bird to walk on the force platform which automatically registered the peak vertical force of the steps. Results showed that the gait score increased with the weight and age of the birds. Peak force asymmetry was found for each foot, independent of age or gait score. Although not identified visually in the broilers, the peak vertical force values differed in both right and left feet leading to slow and uneven walking. Walking deficiency was more severe in older birds.Deficiência em locomoção é hoje um dos problemas mais importantes na produção de frangos de corte. É causa de baixo bem-estar e leva a alteração no comportamento de bebida e alimentação, com conseqüente perda de ganho de peso. Mediram-se deficiências locomotoras em frango de corte por meio da análise do pico de força plantar vertical em ambas as patas, durante a caminhada. Foi construída uma câmara com uma rampa de entrada, uma área horizontal de passagem e uma rampa de saída. Na

  15. Neurological morbidity in vaccine-associated paralytic poliomyelitis in Brazil from 1989 up to 1995

    OpenAIRE

    Dias-Tosta,Elza; Kückelhaus,Carlos Santos

    2004-01-01

    We collected 30 cases of vaccine associated paralytic poliomyelitis (VAPP) from 4081 cases of acute flaccid palsies cases notified from 1989 to 1995 to the Brazilian Ministry of Health. There were 30 VAPP cases with 56% of children younger than 1 year old, 56.7% of female. 46% of cases were reported in the Northeast. Ten P2 vaccine virus, 8 P3 and 2 P1 and associations amongst them were isolated. The clinical pattern in 60 days was: monoplegia (16), paraplegia (6), tetraplegia (5), hemiplegia...

  16. Some features of one-year-old tart Cherry shoots of cv. Sehattenmorelle

    Directory of Open Access Journals (Sweden)

    Dariusz Świetlik

    2013-12-01

    Full Text Available The purpose of this study was to obtain data on the relationship between the length of 1-year-old shoots and their fruiting, and both their terminal and lateral growtn produced in the current year. The measurements were taken in 1977 and 1979 from the tart cherry trees of cv. Schattenmorelle grafted of Prunus mahaleb L. or Prunus avium L. grown in loose sandy soil. In 1977 there were more shoots of over 30 cm than in 1979. The longer the shoots, the more lateral shoots were there. Only the shortest shoots (1-10 cm bore more fruit per unit length as compared to the longer shoots.

  17. Comparative studies on the growth of pinus brutia in pure and mixed plantations

    Energy Technology Data Exchange (ETDEWEB)

    Hasan, S.M.; Al-Saraf, M.J.; Khalil, M.T.

    1980-01-01

    In trials in a semi-arid poor soil in Hammam Al-Alil, Mosul, Iraq, 2-year-old P. brutia transplants were planted in two blocks at 1x1 spacing. One block was interplanted with 1-year-old Acacia farnesiana. There was n.s.d. in growth of P. brutia between the 2 blocks at the end of the first or second year, but height growth in the mixed stand was significantly greater than in the pure stand after 3 growing seasons. (Refs. 10).

  18. Cognitive function and neurodevelopmental outcomes in HIV-infected Children older than 1 year of age randomized to early versus deferred antiretroviral therapy: the PREDICT neurodevelopmental study.

    OpenAIRE

    Puthanakit, T.; Ananworanich, J.; Vonthanak, S.; Kosalaraksa, P; Hansudewechakul, R; Lugt, J. van der; Kerr, SJ; Kanjanavanit, S.; Ngampiyaskul, C.; Wongsawat, J; Luesomboon, W.; Vibol, U.; Pruksakaew, K; Suwarnlerk, T; Apornpong, T

    2013-01-01

    We previously reported similar AIDS-free survival at 3 years in children who were >1 year old initiating antiretroviral therapy (ART) and randomized to early versus deferred ART in the Pediatric Randomized to Early versus Deferred Initiation in Cambodia and Thailand (PREDICT) study. We now report neurodevelopmental outcomes.Two hundred eighty-four HIV-infected Thai and Cambodian children aged 1-12 years with CD4 counts between 15% and 24% and no AIDS-defining illness were randomized to initia...

  19. Recurrent Multiple Squamous Cell Carcinomas on the Scalp in a Patient with Juvenile Dermatomyositis

    Science.gov (United States)

    Sato, Yota; Fujimura, Taku; Kambayashi, Yumi; Tsukada, Akira; Hidaka, Takanori; Tanita, Kayo; Haga, Takahiro; Hashimoto, Akira; Aiba, Setsuya

    2017-01-01

    Both long-term administration of immunosuppressive agents and chronic inflammatory conditions, such as autoimmune disease, could be risk factors for the development of cutaneous squamous cell carcinoma (cSCC). In this report, we present a case of recurrent multiple cSCC on the scalp in a patient with juvenile dermatomyositis who had been administered cyclosporine and Predonine since she was a 1-year-old infant. Interestingly, immunohistochemical staining revealed IL-17-producing cells adjacent to IL-17R-expressing atypical keratinocytes. Our present case suggested that IL-17/IL-17R signaling might contribute to the carcinogenesis of cSCC. PMID:28203172

  20. Evaluation of Mird and Marinelli formalisms in the radiation dosimetry for thyroid of adults and children using {sup 131I} (radioiodine); Evaluacion de las dosimetrias Mird y de Marinelli en el estimado de dosis de radiacion para tiroides de adultos y ninos cuando se usa {sup 131}I (yoduro)

    Energy Technology Data Exchange (ETDEWEB)

    Vasquez, A.M.; Rocha, J.J.; Castillo, D.C.; Gomez, M.A.; Mendoza, A.A.; Rabanal, M.J.; Cruz, S.J. [Universidad Nacional de Trujillo (UNT-UCV), Trujillo (Peru). Grupo de Fisica Medica

    2013-11-01

    Using MIRD formalism and Cristy-Eckerman representation for the thyroid adults, children of 15, 10, 5, 1 year old and newborn it is shown that the total dose absorbed by the gland due to {sup 131}I(iodine) is its self-dose. Their results are not significantly different from those reported by the formalism MARINELLI (self-dose), which uses a sphere as glandular representation. Consequently, the kinetic model to the gland is a single compartment and the thyroid can be represented as a sphere.

  1. VOLTAGE-GATED NA+ CHANNEL BLOCKERS ATTENUATE THE TOXICITY OF PROLONGED REPETITIVE ACTIVITY IN A MOUSE MODEL OF CMT1B

    DEFF Research Database (Denmark)

    Alvarez Herrero, Susana; Rosberg, M. R.; Moldovan, M.

    2016-01-01

    Prolonged high frequency electrical stimulation (RS) was found to precipitate motor axon degeneration in P0+/− mice, a model of demyelinating Charcot-Marie-Tooth disease (CMT1B). We hypothesized that this was due to the associated changes in voltage-gated Na + channel (VGSC) isoforms with ectopic.......). Investigations were carried out in 1-year-old WT, P0+/− and NaV1.8 knockouts (P0+/−SNS) mice. Tibial nerve RS was carried out under anesthesia using interrupted trains of 200 Hz for 3 hours, which is not neurotoxic in WT. Nerve function was monitored by conventional conduction studies and nerve excitability...

  2. The effect of β-sitosterol on the metabolism of cholesterol and lipids in rats on a diet containing coconut oil

    Science.gov (United States)

    Gerson, T.; Shorland, F. B.; Dunckley, G. G.

    1965-01-01

    1. Intraperitoneal injection of β-sitosterol (5mg./rat/day for 25 days) into 1-year-old male Wistar rats fed on a low-fat diet supplemented with 10% of coconut oil resulted in a lowering of cholesterol and lipid concentrations in the tissues. 2. β-Sitosterol increased the rate of biosynthesis of cholesterol and lipids in the tissues, but to an even greater extent enhanced their oxidative degradation. 3. The present results are similar to those previously obtained on a low-fat diet, indicating that the presence of fat had no marked effect on the action of β-sitosterol. PMID:5891218

  3. Imaging diagnosis: fibrodysplasia ossificans progressiva in a cat.

    Science.gov (United States)

    Klang, Andrea; Kneissl, Sibylle; Glänzel, Romana; Fuchs-Baumgartinger, Andrea

    2013-01-01

    A 1-year-old female cat was presented for progressive alopecia, gait abnormalities, and stiffness. Radiography demonstrated multiple calcified lesions within the soft tissues of the cervical and thoracic spine, shoulder, and limbs. Postmortem computed tomography provided more detailed information on the distribution, pattern, and extension of lesions. In addition, computed tomography helped guide sample selection for histopathology. The final diagnosis was fibrodysplasia ossificans progressiva. This is a rare disorder of unknown etiology, characterized by fibrosis and heterotopic bone formation in connective tissues. To the authors' knowledge, this is the first report describing this disease in a European cat.

  4. Malnutrition during lactation as a metabolic imprinting factor inducing the feeding pattern of offspring rats when adults: The role of insulin and leptin

    OpenAIRE

    MOURA,A.S.; Franco de Sá,C.C.N.; Cruz,H.G.; C. L. Costa

    2002-01-01

    The aim of the present study was to determine the impact of malnutrition during early postnatal life and the feeding pattern of rat offspring when adults (2 months and 1 year old). In comparison with rats normally fed during lactation, we observed that adult offspring displayed a faster process of feeding reduction when a protein-free diet was offered. In addition, we studied the concentration of insulin and leptin in the lactating pups (10 days) and when these offspring became adult after th...

  5. Meningitis due to Haemophilus influenzae type f.

    Science.gov (United States)

    Cardoso, Marta Pessoa; Pasternak, Jacyr; Giglio, Alfredo Elias; Casagrande, Rejane Rimazza Dalberto; Troster, Eduardo Juan

    2013-12-01

    With the decline in the rate of infections caused by Haemophilus influenzae serotype b since the widespread vaccination, non-b serotypes should be considered as potential pathogenic agents in children with invasive disease younger than 5 years old. We report the case of an immunocompetent 1-year-old boy with Haemophilus influenzae type f meningitis. The agent was identified in cerebrospinal fluid and blood cultures. Serotyping was performed by tests using polyclonal sera and confirmed by polymerase chain reaction. All Haemophilus influenzae isolates associated with invasive disease should be serotyped and notified as a way to evaluate the changes and trends in serotype distribution of this disease.

  6. Familial dysautonomia (Riley-Day syndrome).

    Science.gov (United States)

    Tonholo-Silva, E R; Takahashi, S I; Yoshinaga, L

    1994-03-01

    Familial dysautonomia, also known as Riley-Day syndrome, is a disorder of autonomic nervous system with an autosomal recessive mode of inheritance. Reduction and/or loss of unmyelinated and small myelinated fibers is found, as reduction of dopamine beta-hydroxylase in blood. The diagnosis is based on clinical features: diminished lacrimation, insensitivity to pain, poor temperature control, abolished deep tendon reflexes, postural hypotension, vomiting attacks, poor motor coordination, and mental retardation. The treatment is symptomatic and many children die during the first years of life, usually as a result of repeated aspiration pneumonia. We report the case of a 1 year-old child with familial dysautonomia.

  7. Familial dysautonomy (Riley-Day syndrome

    Directory of Open Access Journals (Sweden)

    Edward R. Tonholo Silva

    1994-03-01

    Full Text Available Familial dysautonomia, also known as Riley-Day syndrome, is a disorder of autonomic nervous system with an autosomal recessive mode of inheritance. Reduction and/or loss of unmyelinated and small myelinated fibers is found, as reduction of dopamine beta-hydroxylase in blood. The diagnosis is based on clinical features: diminished lacrimation, insensitivity to pain, poor temperature control, abolished deep tendon reflexes, postural hypotension, vomiting attacks, poor motor coordenation, and mental retardation. The treatment is symptomatic and many children die during the first years of life, usually as a result of repeated aspiration pneumonia. We report the case of a 1 year-old child with familial dysautonomia.

  8. The arbuscular mycorrhizal status of poplar clones selected for phytoremediation of soils contaminated with heavy metals

    Energy Technology Data Exchange (ETDEWEB)

    Takacs, T.; Radimszky, L.; Nemeth, T. [Research Inst. for Soil Science and Agricultural Chemistry of the Hungarian Academy of Sciences, Budapest (Hungary)

    2005-04-01

    The aim of this work was to study the colonization of indigenous arbuscular mycorrhizal fungi (AMF) species in fine-roots of poplar clones. Roots of 7 poplar clones were sampled from a 1-year-old trial established at an industrial site strongly polluted with heavy metals at Balatonfuezfoe, Hungary. The poplar clones have shown variable degrees of colonization by AMF, suggesting differential host susceptibility or mycorrhizal dependency. After outplanting the percentage of poplar survival was strongly correlated with the frequency of AMF infection. Two clones that survived at the lowest ratio after outplanting had not been colonized by AMF in contrast to those which survived to a much higher extent. (orig.)

  9. A new neonatal case of N-acetylglutamate synthase deficiency treated by carbamylglutamate.

    Science.gov (United States)

    Guffon, N; Vianey-Saban, C; Bourgeois, J; Rabier, D; Colombo, J P; Guibaud, P

    1995-01-01

    N-Acetylglutamate synthase (NAGS) deficiency is a rare, autosomal recessive urea-cycle disease. Its clinical presentation is not different from the other hereditary hyperammonaemias. We report a new neonatal case with hyperammonaemic coma. A test by carbamylglutamate was performed at 25 days of life. Since then, the child was treated by carbamylglutamate three or four times a day with a total dose of 80-100 mg/kg per day. Today, the boy is 1 year old. He receives carbamylglutamate 200 mg four times a day. He has normal somatic and neurological development and good metabolic balance.

  10. Mycorrhizae of Japanese black pine (Pinus thunbergii): Protection of seedlings from acid mist and effect of acid mist on mycorrhiza formation

    Energy Technology Data Exchange (ETDEWEB)

    Maehara, Noritoshi; Kikuchi, Junichi; Futai, Kazuyoshi

    1993-01-01

    To determine the effects of acid precipitation on Japanese black pine (Pinus thunbergii Parl.) with and without mycorrhizae (Pisolithus tinctorius (Pers.) Coker et Couch), 1-year-old seedlings were exposed to simulated acid rain mist, pH 3.0, for 10 min per day twice a week for 3 or 4 months. Simulated acid mist adversely affected the transpiration rate and lowered the extractable phosphorus content on seedlings, but seedlings with mycorrhizae were less affected by acid mist than were nonmycorrhizal seedlings. Simulated acid mist also retarded mycorrhiza formation. 41 refs., 7 figs.

  11. Brain stem hypoplasia associated with Cri-du-Chat syndrome.

    Science.gov (United States)

    Hong, Jin Ho; Lee, Ha Young; Lim, Myung Kwan; Kim, Mi Young; Kang, Young Hye; Lee, Kyung Hee; Cho, Soon Gu

    2013-01-01

    Cri-du-Chat syndrome, also called the 5p-syndrome, is a rare genetic abnormality, and only few cases have been reported on its brain MRI findings. We describe the magnetic resonance imaging findings of a 1-year-old girl with Cri-du-Chat syndrome who showed brain stem hypoplasia, particularly in the pons, with normal cerebellum and diffuse hypoplasia of the cerebral hemispheres. We suggest that Cri-du-Chat syndrome chould be suspected in children with brain stem hypoplasia, particularly for those with high-pitched cries.

  12. Spontaneous thrombosis of a giant cerebral varix in a pediatric patient.

    Science.gov (United States)

    Ozturk, Mesut; Aslan, Serdar; Ceyhan Bilgici, Meltem; Idil Soylu, Aysegul; Aydin, Keramettin

    2017-07-20

    Cerebral cortical venous aneurysm also known as cerebral varix is a rare entity that usually occurs in relation to high-flow draining veins of arteriovenous fistulas, arteriovenous malformations, and venous angioma. Isolated cerebral varix is an extremely rare entity. We present a 1-year-old male with isolated cerebral varix. During follow-up, the varix thrombosed spontaneously without causing any neurological deficits. To the best of our knowledge, spontaneous asymptomatic thrombosis of an isolated cerebral varix without any clinical finding was reported for the first time in the literature.

  13. Increasing rate of middle ear ventilation tube insertion in children in denmark

    DEFF Research Database (Denmark)

    Djurhuus, Bjarki Ditlev; Skytthe, Axel; Christensen, Kaare;

    2014-01-01

    ear ventilation tube insertion performed in Denmark in the period were identified. A possible change in incidence rate over time was examined using Poisson regression analysis, while the cumulative incidence proportion was estimated using life-tables. RESULTS: A total of 502,569 uni- or bilateral...... in incidence rate was found in 1-year-olds with an annual increase of 4.5% (95% confidence interval 4.4-4.6%). Age-specific incidence rates remained at maximum around the age of 14 months throughout the period. The cumulative incidence proportion for the 2010 birth cohort by the time they reach the age of 5...

  14. Ameloblastic fibroma in one-year-old girl.

    Science.gov (United States)

    Munde, Anita D; Karle, Ravindra R; Kale, Ujwala B

    2013-01-01

    Ameloblastic fibroma (AF) is a relatively rare, slow growing benign mixed odontogenic tumor, comprising of 1.5-4.5% of all odontogenic tumors. It is usually asymptomatic except for the eventual expansion of the jaw. AFs are most common in adolescents and young adults, mostly affecting the mandible as a well-defined uni or multilocular radiolucency. The effective surgical treatment includes enucleation and curettage of the surrounding bone and removal of the affected teeth. Although recurrence of AF is rare, a long term follow up is recommended. This report describes a 1-year-old girl with AF in the mandible and discusses its clinical, radiographic and histological findings.

  15. Failure of peritoneal and gallbladder shunts in a child with craniopharyngioma

    Directory of Open Access Journals (Sweden)

    Julie Woodfield

    2013-01-01

    Full Text Available A 1-year-old girl with craniopharyngioma required external drainage of 40-50 mL/h of cerebrospinal fluid (CSF after biopsy and cyst fenestration. She developed CSF ascites following insertion of a ventriculoperitoneal (VP shunt and a distended painful gallbladder following ventriculogallbladder shunt insertion. Revision to a ventriculoatrial shunt was required. This is the first time a craniopharyngioma has been reported to cause increased CSF production. The potential mechanisms of CSF overproduction and the difficulties managing the large volume of CSF in a young child are discussed.

  16. A case of congenital hypothyroidism presented with dysmyelinization findings

    Institute of Scientific and Technical Information of China (English)

    Sevil Ar Yuca; Cahide Ylmaz; Avni Kaya; Lokmanstyol; Ertan Sal; Yasar Cesur; Hseyin Caksen

    2014-01-01

    The central nervous system is one of the most crucial targeted systems of hyphotiroidism where tissues undergo various broad developmental processes such as neuronal and glial cellular differentiation, migration and myelinization.However brain images are mainly normal.In this article we present findings related to a1-year-old girl who has been referred to our outpatient clinic with complaints of slowing of movement and lack of interest.She was diagnosed with hypothyroidism.Her brain magnetic resonance image obtained during diagnosis displayed dysmyelinization.It showed improvement afterNa-L thyroxin therapy during follow up.

  17. Salmonella bongori 48:z35:– The first Italian case of human infection outside Sicily

    Directory of Open Access Journals (Sweden)

    Alberto Bellio

    2016-10-01

    Full Text Available Salmonella bongori 48:z35:– is considered endemic to Sicily (Italy due to its epidemiological peculiarity. To our knowledge, no previous cases of human infection caused by S. bongori 48:z35:– have ever been reported in mainland Italy. Here we describe the isolation of S. bongori 48:z35:– from a 1-year-old symptomatic child in northwest Italy (Piedmont Region. The strain showed no antimicrobial resistance. Reporting of S. bongori 48:z35:– in a previously safe area is important to identify epidemiological changes.

  18. Feeding and oral hygiene habits of preschool children in Hong Kong and their caregivers' dental knowledge and attitudes

    OpenAIRE

    King, NM; Chan, SCL; Tsai, JSJ

    2002-01-01

    Objectives. This study was designed to gather data on infant feeding habits and oral hygiene practices of Hong Kong preschool children, on the dental knowledge and attitudes of their caregivers and on the oral health status of the same group of children. Design. Cross-sectional study. Sample and methods. Data was gathered for a total of 369 boys and 297 girls (207 1-year-olds, 269 2-year-olds and 190 3-year-olds) with a mean age of 20-19 (± 0.38) months. Information related to children attend...

  19. Brain stem hypoplasia associated with Cri-du-Chat syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Jin Ho; Lee, Ha Young; Lim, Myung Kwan; Kim, Mi Young; Kang, Young Hye; Lee, Kyung Hee; Cho, Soon Gu [Dept. of Radiology, Inha University Hospital, Inha University School of Medicine, Incheon (Korea, Republic of)

    2013-12-15

    Cri-du-Chat syndrome, also called the 5p-syndrome, is a rare genetic abnormality, and only few cases have been reported on its brain MRI findings. We describe the magnetic resonance imaging findings of a 1-year-old girl with Cri-du-Chat syndrome who showed brain stem hypoplasia, particularly in the pons, with normal cerebellum and diffuse hypoplasia of the cerebral hemispheres. We suggest that Cri-du-Chat syndrome chould be suspected in children with brain stem hypoplasia, particularly for those with high-pitched cries.

  20. Case of cytomegalovirus-associated direct anti-globulin test-negative autoimmune hemolytic anemia.

    Science.gov (United States)

    Kaneko, Saeko; Sato, Masanori; Sasaki, Goro; Eguchi, Hiroyuki; Oishi, Tsutomu; Kamesaki, Toyomi; Kawaguchi, Hiroyuki

    2013-12-01

    A 1-year-old boy developed autoimmune hemolytic anemia after a negative direct anti-globulin test. The concentration of erythrocyte membrane-associated immunoglobulin G, determined using an immunoradiometric assay, correlated with disease activity. He was positive for cytomegalovirus (CMV) both serologically and by quantitative real-time polymerase chain reaction, indicating that his autoimmune hemolytic anemia was directly caused by CMV infection. Since anti-CMV immunoglobulin G was not absorbed by the patient's erythrocytes, cross-reaction between erythrocyte antigens and CMV was not likely a causative factor for hemolysis.

  1. Perforated ileal duplication cyst with haemorrhagic pseudocyst formation

    Energy Technology Data Exchange (ETDEWEB)

    Hwang, Im Kyung; Kim, Bong Soo; Kim, Heung Chul; Lee, In Sun; Hwang, Woo Chul [Department of Radiology, College of Medicine, Hallym University (Korea); Namkung, Sook [Department of Radiology, College of Medicine, Hallym University (Korea); Department of Radiology, Chuncheon Sacred Heart Hospital, 153 Kyo-dong, Chuncheon, Kangwon-do, 200-704 (Korea)

    2003-07-01

    Duplication cysts of the gastrointestinal tract are rare congenital abnormalities. Ectopic gastric mucosa, which can be found in duplications, may cause peptic ulceration, gastrointestinal bleeding or perforation. We report a 1-year-old boy with a perforated ileal duplication cyst with haemorrhagic pseudocyst formation caused by peptic ulceration of the duplication cyst. It presented a snowman-like appearance consisting of a small, thick-walled, true enteric cyst and a large, thin-walled haemorrhagic pseudocyst on US and CT. It is an unusual manifestation of a duplication cyst, which has not been reported in the English language literature. (orig.)

  2. Age-specificity of Toxoplasma gondii seroprevalence in sheep, goats and cattle on subsistence farms in Bangladesh.

    Science.gov (United States)

    Rahman, Moizur; Azad, Md Thoufic Anam; Nahar, Lovely; Rouf, Shah Md Abdur; Ohya, Kenji; Chiou, Shih-Pin; Baba, Minami; Kitoh, Katsuya; Takashima, Yasuhiro

    2014-09-01

    Toxoplasma gondii is a zoonotic protozoan parasite that infects humans and domestic animals. In this study, the seroprevalence of T. gondii antibodies was investigated using serum samples collected from 83 sheep, 146 goats and 37 cattle from a dozen subsistence farms in Bangladesh. Fifty-eight out of 83 sheep (69.9%), 89 out of 146 goats (61.0%) and 10 out of 37 cattle (27.0%) were seropositive for the parasite. Seroprevalence in young goats (goats (>1 year old). In contrast, seroprevalence for young and adult sheep was similar. These results indicate that acquired infection with T. gondii occurs in this region of Bangladesh, at least among goats.

  3. [Bilateral persistent hyaloid artery. A case report].

    Science.gov (United States)

    Borbolla-Pertierra, A M; Martínez-Hernández, C K; Juárez-Echenique, J C

    2014-06-01

    A 5-year-old male presented with bilateral poor vision, esotropia and a previous diagnosis of cataract since he was 1 year old. The physical examination revealed bilateral posterior paracentric capsule opacification, vitreous cavity with a permeable pulsatile blood filled hyaloid artery in both eyes. He was kept under observation. Persistent hyaloid artery is an uncommon faulty primary vitreous regression, often unilateral (although it may be bilateral) and sporadic, associated with microphthalmos. It may be complicated with glaucoma and phthisis bulbi. Vitrectomy plus lensectomy or simple observation are the accepted treatment options. Copyright © 2012 Sociedad Española de Oftalmología. Published by Elsevier Espana. All rights reserved.

  4. Convergent Strabismus in a Cat and It’s Surgical Treatment

    Directory of Open Access Journals (Sweden)

    Murat KİBAR

    2017-01-01

    Full Text Available The aim of this study was to improve visual acuity and esthetic correction in a short hair domestic cat with strabismus. A domestic short hair cat (1 year old, male referred with visual deficit and progressively obvious strabismus. For recession surgery, medial rectus muscle was detached from the sclera after used suspensory suture. The muscle insertion was recessed 4 mm and sutured to sclera. In conclusion, strabismus can be caused to visual deficy and treated succesfully by recession surgery in cats.

  5. Brain CT scanning of children with purulent meningitis

    Energy Technology Data Exchange (ETDEWEB)

    Mishima, M.; Suzuki, M.; Nagata, M.; Kawamura, G.

    1986-12-01

    Nine of 21 children with purulent meningitis showed abnormal findings in brain CT when admitted. All of the abnormal group were less than 12 months of age, but 75 % of the normal group were more than 1 year old. The period of positive CRP was longer and the level of sugar in CSF was lower in abnormal group when compared with normal group. Because convulsion and EEG abnormalities were observed similarly in both groups, it may be difficult to determine the organic changes of the brain clinically. Brain CT scanning is recommended as soon as possible after the onset of purulent meningitis.

  6. Differences in MRI findings between subgroups of recent-onset childhood arthritis

    Energy Technology Data Exchange (ETDEWEB)

    Kirkhus, Eva [Oslo University Hospital, Rikshospitalet, Department of Radiology, Oslo (Norway); Flatoe, Berit; Smith, Hans-Joergen [Oslo University Hospital, Rikshospitalet and University of Oslo, Faculty of Medicine, Department of Radiology, Oslo (Norway); Riise, Oeystein [Oslo University Hospital, Rikshospitalet, Department of Pediatrics, Oslo (Norway); Reiseter, Tor [Oslo University Hospital, Ullevaal, Department of Radiology, Oslo (Norway)

    2011-04-15

    MRI is sensitive for joint inflammation, but its ability to separate subgroups of arthritis in children has been questioned. Infectious arthritis (IA), postinfectious arthritis (PA), transient arthritis (TA) and juvenile idiopathic arthritis (JIA) are subgroups that may need early, different treatment. To determine whether MRI findings differ in IA, PA/TA and JIA in recent-onset childhood arthritis. Fifty-nine children from a prospective study of incidence of arthritis (n = 216) were, based on clinical and biochemical criteria, examined by MRI. Joint fluid, synovium, bone marrow, soft tissue and cartilage were scored retrospectively and analysed by Pearson chi-square test and logistic regression analysis. Fifty-nine children had MRI of one station. IA was suggested by bone marrow oedema (OR 7.46, P = 0.011) and absence of T1-weighted and T2-weighted low signal intensity synovial tissue (OR 0.06, P = 0.015). Furthermore, soft-tissue oedema and reduced contrast enhancement in the epiphyses were more frequent in children with IA. JIA correlated positively with low signal intensity synovial tissue (OR 13.30, P < 0.001) and negatively with soft-tissue oedema (OR 0.20, P = 0.018). No significant positive determinants were found for PA/TA, but bone marrow oedema, soft-tissue oedema, irregular thickened synovium and low signal intensity synovial tissue was less frequent than in IA/JIA. In children with high clinical suspicion of recent onset arthritis, there was a significant difference in the distribution of specific MRI features among the diagnostic groups. (orig.)

  7. Interspecies scaling of the pharmacokinetics of N-nitrosodimethylamine.

    Science.gov (United States)

    Gombar, C T; Harrington, G W; Pylypiw, H M; Anderson, L M; Palmer, A E; Rice, J M; Magee, P N; Burak, E S

    1990-07-15

    The pharmacokinetics of N-nitrosodimethylamine was studied in patas monkeys following i.v. doses of 0.5, 1.0, and 5.0 mg/kg and a p.o. dose of 1.0 mg/kg, and in Swiss mice at i.v. doses of 1.0 and 2.0 mg/kg. In the patas monkey the pharmacokinetics was linear over the i.v. dose range studied. The mean clearance (Cl), steady-state volume of distribution (Vss), mean residence time, and elimination half-life (t 1/2) were 103.3 +/- 26.7 (SD) ml/min, 3061 +/- 821 ml, 30.8 +/- 10.8 min, and 21.1 +/- 8.5 min, respectively. Assuming that the pharmacokinetics was linear at the p.o. dose used, the p.o. bioavailability of N-nitrosodimethylamine in the monkey was 49%. The pharmacokinetics was also linear in mice, and the average Cl, Vss, mean residence time, and t 1/2 were 3.81 ml/min, 21.0 ml, 5.5 min, and 11.9 min, respectively. These data and data for rats, hamsters, rabbits, dogs, and pigs taken from the literature were used to scale Cl and Vss to body weight using the allometric equation. The resulting equation for Cl was Cl = 49.7B0.998 and the equation for Vss was Vss = 748B1.05 where B is body weight in kg. The fit of the data to the equation was excellent in both cases. Using these equations and assuming a body weight of 70 kg for humans, the Cl and Vss for N-nitrosodimethylamine in humans are estimated to be 3450 ml/min and 64,800 ml, respectively.

  8. Antagonistas serotoninérgico e noradrenérgico por via subaracnoidea aumentam a resposta álgica em ratos

    Directory of Open Access Journals (Sweden)

    Oscar César Pires

    2011-04-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Há evidências de que a passagem de informações nociceptivas pelo corno posterior da medula espinhal (CPME seguindo para níveis rostrais do sistema nervoso central sofre profundas influências excitatórias e inibitórias. A presente pesquisa teve como objetivo comparar os efeitos da metissergida, da fentolamina e da fentolamina associada à metissergida, administrados por via subaracnoidea, sobre as fases I, intermediária e II do teste da formalina modificado em ratos. MÉTODO: Foram utilizados 28 ratos Wistar machos, distribuídos aleatoriamente em quatro grupos (n = 7 para receber solução salina (GC, fentolamina (GF, metissergida (GM ou fentolamina associada à metissergida (GFM por via subaracnoidea. A dor foi induzida pela administração de formalina na região dorsal da pata posterior direita. O teste foi dividido em três fases; fase I, intermediária e fase II. A análise estatística dos resultados foi realizada utilizando o programa SPSS (Statistical Package for Social Sciences, adotando o nível de significância de 5%. RESULTADOS: Na fase intermediária, o número de elevações da pata foi significativamente maior nos grupos GF, GM e GFM quando comparados com o grupo GC. CONCLUSÕES: Os resultados sugerem a existência de efeito noradrenérgico e serotoninérgico no sistema inibitório descendente da dor aguda, com a possibilidade de emprego de agonistas serotoninérgicos e α1-adrenérgicos para controle da dor aguda.

  9. Morphologic features of Sancassania berlesei (Acari: Astigmata: Acaridae), a common mite of stored products in China.

    Science.gov (United States)

    Li, Chaopin; Jiang, Yuxin; Guo, Wei; Chen, Qi

    2015-04-01

    Objetivo: sancassania berlesei (S. berlesei) es el lider en la industria de cría amenaza mite eupolyphaga sinensis y la salud pública.Métodos: los especimenes vivos de S. berlesei fueron obtenidos a partir de la superficie de eupolyphaga sinensis y purificado con agua bidestilada.El huevo, larva, ninfa, hypopus, macho adulto y la hembra de S. berlesei fueron evaluados y elegidos bajo microscopio.Resultados: las variaciones morfológicas de S. berlesei, incluidas sus piernas, setas, genitales externos y accesorios, están claramente identificadas en la SEM.La larva tiene tres pares de patas, sin hojas como setas, pero su coxal Rod es desarrollada.Por la etapa de ninfa, cuatro pares de patas y el cuarto dorsal seta surgen, mientras que la zona genital se ve aún en desarrollo.En hypopus, las garras y tarsules aparecen bien construido, y la hoja como setas, setas de tibia y setas de Genu son vistos.La ventosa plato totalmente contiene nueve retoños y cuatro Shell como dimplings en que hay distribuciones simétricas con 1 par de mamones, 2 pares de lado anterior de ventosas y 1 par de tontos, respectivamente.Una pera como posterior ventosa está ubicado en la espalda de Sucker plato.Todos los tontos son suaves excepto anterior Sucker con franja radial.El órgano de sentido genital adultos exhibe con cordiforme aspecto externo y osificación típica textura; mientras que el macho es diferente con la hembra respecto a seta numero en el sentido de órganos genitales.Conclusión: descripción de la estructura morfologica en gran detalle para S. berlesei tiende a suministrar la información importante para la taxonomía y más estudio.

  10. Reconhecimento e uso de plantas medicinais pelos idosos do Município de Marmeleiro - Paraná

    Directory of Open Access Journals (Sweden)

    S. Balbinot

    2013-01-01

    Full Text Available O consumo de plantas medicinais tem base na tradição familiar e tornou-se prática generalizada na medicina popular. Neste sentido, este trabalho teve como objetivo verificar o grau de reconhecimento e uso de espécies medicinais utilizadas por 35 idosos do município de Marmeleiro - Paraná. Os resultados das entrevistas mostraram que todos os idosos conheciam, das vinte plantas medicinais apresentadas, a babosa, a camomila, a erva-cidreira, a macela, a malva, a manjerona, a noz-moscada, a pata-de-vaca e a sálvia. Além disso, 94% dos mesmos faziam o uso de plantas medicinais, sendo que 71,4% destes, utilizavam frequentemente, enquanto 94,2% foram influenciados principalmente pelos familiares (pais e avós. As plantas medicinais consumidas diariamente pelos idosos eram a erva-cidreira (48,6%, a malva (34,3%, o quebra-pedra (34,1%, a sálvia (25,7%, a camomila (22,9%, o guaco (20%, a carqueja e a macela (14,3%, a pata-de-vaca e o alecrim (8,6% e a babosa (2,9%, preparadas na forma de chá (decocção ou infusão. Vale destacar que a forma de obtenção das plantas medicinais era principalmente em plantações próprias (88,6%. Desta forma, informações acerca das plantas medicinais devem retornar para a população, em especial a mais idosa, enfatizando o modo de cultivo e colheita, através de técnicas desconhecidas por eles, bem como a melhor forma de utilização de cada espécie medicinal, estimulando seu uso, com maior eficacia e segurança.

  11. Processing of Phonemic Consonant Length: Semantic and Fragment Priming Evidence from Bengali.

    Science.gov (United States)

    Kotzor, Sandra; Wetterlin, Allison; Roberts, Adam C; Lahiri, Aditi

    2016-03-01

    Six cross-modal lexical decision tasks with priming probed listeners' processing of the geminate-singleton contrast in Bengali, where duration alone leads to phonemic contrast ([pata] 'leaf' vs. [pat:a] 'whereabouts'), in order to investigate the phonological representation of consonantal duration in the lexicon. Four form-priming experiments (auditory fragment primes and visual targets) were designed to investigate listeners' sensitivity to segments of conflicting duration. Each prime derived from a real word ([k(h)[symbol: see text]m]/[g(h)en:]) was matched with a mispronunciation of the opposite duration (*[k(h)[symbol: see text]m:]/*[g(h)en]) and both were used to prime the full words [k(h)[symbol: see text]ma] ('forgiveness') and [g(h)en:a] ('disgust') respectively. Although all fragments led to priming, the results showed an asymmetric pattern. The fragments of words with singletons mispronounced as geminates led to equal priming, while those with geminates mispronounced as singletons showed a difference. The priming effect of the real-word geminate fragment was significantly greater than that of its corresponding nonword singleton fragment. In two subsequent semantic priming tasks with full-word primes a stronger asymmetry was found: nonword geminates (*[k(h)[symbol: see text]m:a]) primed semantically related words ([marjona] 'forgiveness') but singleton nonword primes (*[ghena]) did not show priming. This overall asymmetry in the tolerance of geminate nonwords in place of singleton words is attributed to a representational mismatch and points towards a moraic representation of duration. While geminates require a mora which cannot be derived from singleton input, the additional information in geminate nonwords does not create a similar mismatch.

  12. Atividades antinociceptiva e antiinflamatória do extrato etanólico de Luehea divaricata

    Directory of Open Access Journals (Sweden)

    E.K.F BATISTA

    Full Text Available RESUMO Considerando os diferentes usos etnofarmacológicos apresentados pela planta Luehea divaricata, realizou-se este estudo com o objetivo de avaliar as atividades antinociceptiva e antinflamatória do extrato etanólico de suas folhas, em modelo animal, nas dosagens de 20, 40, 80 e 160 mg/Kg, por via oral. Foram realizados os seguintes testes: contorções abdominais induzidas pelo acido acético, placa quente, formalina e edema de pata induzido por carragenina. Foram utilizados camundongos Swiss (20-25 g para os três primeiros testes e ratos Wistar (180-250 g, para o último, divididos em seis grupos de oito animais, totalizando 48 animais em cada parâmetro de avaliação. Os resultados foram analisados estatisticamente pela análise de variância a 5% de probabilidade, para verificar quais os tratamentos que diferiram entre si, e estes foram submetidos aos testes de Kruskall-Wallis e Student-Newman-Keuls. O extrato etanólico das folhas de L. divaricata (EEtOH-Ld, nas diferentes doses estudadas, apresentou significativa atividade antinociceptiva sobre a dor induzida quimicamente por injeções intraperitoneal de acido acético e intraplantar de formalina. Na dosagem de 160 mg/Kg, esse extrato apresentou ação analgésica central, aos 120 minutos de observação, no teste de placa quente e reduziu o edema de pata induzido pela administração de carragenina, uma hora após a administração do agente inflamatório, semelhante ao efeito produzido pelo fármaco padrão.

  13. Caracterización de las gestantes con cardiopatías en el Hospital Docente Ginecobstétrico “Ramón González Coro”

    Directory of Open Access Journals (Sweden)

    Yanara Gutierrez Aliaga

    2011-11-01

    Full Text Available Introducción: el embarazo en las mujeres cardiópatas constituye hoy, la primera causa de morbi-mortalidad materna entre las patologías asociadas al embarazo. Objetivo: caracterizar a las gestantes con cardiopatía desde el punto de vista clínico y demográfico. Método: estudio observacional, descriptivo y retrospectivo con algunos elementos analíticos, realizado en el Servicio de Cardiopatía y Embarazo del Hospital Docente Ginecobstétrico “Ramón González Coro”, del 2000-2009. El universo estuvo constituido por las 472 gestantes cardiópatas atendidas durante ese periodo y a las que se le aplicó el protocolo diseñado desde el año 2000. Los datos: edad materna, clasificación funcional en primer y tercer trimestres, motivo de ingreso, medicamentos utilizados y complicaciones cardiovasculares, se obtuvieron a través de una encuesta y se procesaron mediante el sistema estadístico SPSS- 11,5, utilizando frecuencias absolutas y relativas. Resultados: las valvulopatías, (25,6 % fue el tipo de cardiopatía más frecuente, se encontraron modificaciones importantes en el grado funcional al terminar el embarazo, se presentaron complicaciones en 29,9 % de las pacientes, las más frecuentes fueron: edema agudo pulmonar (6,4 %, la insuficiencia cardiaca (4,3 % y las arritmias (3,5 %. El tromboembolismo pulmonar fue la causa de las dos muertes maternas que hubo. Conclusión: Las valvulopatías resultaron ser las cardiopatías más frecuentes en nuestras gestantes clasificándose la mayor parte de estas en grado funcionl I y constituyendo el embarazo una agravante potencial para ellas.

  14. Lymphocyte differentiation in sea bass thymus: CD4 and CD8-alpha gene expression studies.

    Science.gov (United States)

    Picchietti, Simona; Guerra, Laura; Buonocore, Francesco; Randelli, Elisa; Fausto, Anna Maria; Abelli, Luigi

    2009-07-01

    Different developmental stages (from eggs to 1-year-old juveniles) of the teleost fish Dicentrarchus labrax (L.) were assayed for CD4 gene expression. RT-PCR revealed the appearance of CD4 transcripts in post-larvae from 51 days post-hatching (dph). This finding overlaps the first detection of CD8-alpha mRNA. Real-time PCR with specific primers quantified CD4, CD8-alpha and TCR-beta transcripts in larvae and post-larvae (25, 51, 75 and 92 dph) and 1-year-old thymus. At 92 dph, TcR-beta and CD8-alpha transcripts were significantly higher (P overlap, except in the medulla, where CD4(+) thymocytes were isolated, while CD8-alpha(+) ones mainly arranged in cords. These results provide new information about the thymic compartmentalization and lymphocyte differentiation pathways in a teleost, almost demonstrating that double negative thymocytes fill the cortex giving rise to further selection in the medulla.

  15. Population variation and individual maximum size in two leech populations: energy extraction from cannibalism or niche widening?

    Science.gov (United States)

    Persson, Lennart; Elliott, J Malcolm

    2013-05-01

    The theory of cannibal dynamics predicts a link between population dynamics and individual life history. In particular, increased individual growth has, in both modeling and empirical studies, been shown to result from a destabilization of population dynamics. We used data from a long-term study of the dynamics of two leech (Erpobdella octoculata) populations to test the hypothesis that maximum size should be higher in a cycling population; one of the study populations exhibited a delayed feedback cycle while the other population showed no sign of cyclicity. A hump-shaped relationship between individual mass of 1-year-old leeches and offspring density the previous year was present in both populations. As predicted from the theory, the maximum mass of individuals was much larger in the fluctuating population. In contrast to predictions, the higher growth rate was not related to energy extraction from cannibalism. Instead, the higher individual mass is suggested to be due to increased availability of resources due to a niche widening with increased individual body mass. The larger individual mass in the fluctuating population was related to a stronger correlation between the densities of 1-year-old individuals and 2-year-old individuals the following year in this population. Although cannibalism was the major mechanism regulating population dynamics, its importance was negligible in terms of providing cannibalizing individuals with energy subsequently increasing their fecundity. Instead, the study identifies a need for theoretical and empirical studies on the largely unstudied interplay between ontogenetic niche shifts and cannibalistic population dynamics.

  16. Seasonal intermittent preventive treatment for the prevention of anaemia and malaria in Ghanaian children: a randomized, placebo controlled trial.

    Directory of Open Access Journals (Sweden)

    Margaret Kweku

    Full Text Available BACKGROUND: Malaria and anaemia are the leading causes of morbidity and mortality in children in sub-Saharan Africa. We have investigated the effect of intermittent preventive treatment with sulphadoxine-pyrimethamine or artesunate plus amodiaquine on anaemia and malaria in children in an area of intense, prolonged, seasonal malaria transmission in Ghana. METHODS: 2451 children aged 3-59 months from 30 villages were individually randomised to receive placebo or artesunate plus amodiaquine (AS+AQ monthly or bimonthly, or sulphadoxine-pyrimethamine (SP bimonthly over a period of six months. The primary outcome measures were episodes of anaemia (Hb1 year old when they received IPTc compared to the placebo group. However the incidence of malaria in the post intervention period was higher in children who were <1 year old when they received AS+AQ monthly compared to the placebo group. INTERPRETATION: IPTc is safe and efficacious in reducing the burden of malaria in an area of Ghana with a prolonged, intense malaria transmission season. TRIAL REGISTRATION: ClinicalTrials.gov NCT00119132.

  17. PMCV and PRV occurrence in wild and farmed fish in Denmark

    DEFF Research Database (Denmark)

    Mikkelsen, Susie Sommer; Arnö, J.; Bruun, Morten Sichlau

    -virus in the family of Reoviridae, while Piscine myocarditis virus (PMCV) is a double-stranded RNA virus of the Totiviridae family. Wild and farmed salmon and trout have not been tested for PRV or PMCV in Denmark before, but both viruses are found in Norway, where they are suspected of causing Heart and Skeletal......Every year salmon are restocked in the 7 rivers Storå, Skjern Å, Varde Å, Sneum Å, Kongeå, Ribe Å and Gudenåen. Six-month-old and 1-year-old salmon for about 2 mio. Kr (€268000) are restocked every year. The salmon are restocked in both the main rivers as well as the larger inlets. 6-month......-old salmon are restocked in smaller rivers where the spawning and growth is ideal. They are released from a boat drifting downstream between September and October. 1-year-old smolt are restocked in a few places in the main rivers in April. They are restocked in large numbers to provide better protection...

  18. A Computational Growth Model for Measuring Dynamic Cortical Development in the First Year of Life

    Science.gov (United States)

    Nie, Jingxin; Li, Gang; Wang, Li; Gilmore, John H.; Lin, Weili

    2012-01-01

    Human cerebral cortex develops extremely fast in the first year of life. Quantitative measurement of cortical development during this early stage plays an important role in revealing the relationship between cortical structural and high-level functional development. This paper presents a computational growth model to simulate the dynamic development of the cerebral cortex from birth to 1 year old by modeling the cerebral cortex as a deformable elastoplasticity surface driven via a growth model. To achieve a high accuracy, a guidance model is also incorporated to estimate the growth parameters and cortical shapes at later developmental stages. The proposed growth model has been applied to 10 healthy subjects with longitudinal brain MR images acquired at every 3 months from birth to 1 year old. The experimental results show that our proposed method can capture the dynamic developmental process of the cortex, with the average surface distance error smaller than 0.6 mm compared with the ground truth surfaces, and the results also show that 1) the curvedness and sharpness decrease from 2 weeks to 12 months and 2) the frontal lobe shows rapidly increasing cortical folding during this period, with relatively slower increase of the cortical folding in the occipital and parietal lobes. PMID:22047969

  19. Response to seasonal drought in three cultivars of Ceratonia siliqua: leaf growth and water relations.

    Science.gov (United States)

    Correia, M J; Coelho, D; David, M M

    2001-07-01

    Responses of leaf growth and leaf water relations to seasonal drought were monitored during two successive years in three cultivars (Galhosa, Espargal and Mulata) of Ceratonia siliqua L. growing in the field in southern Portugal. Leaf water relations of fully expanded leaves were characterized by pressureâ volume analysis, and morphometric measurements of petiolar xylem were made. The three cultivars differed with respect to onset of leaf initiation. In Galhosa, there was a sharp peak of leaf initiation in June that was immediately followed by a period when leaf expansion rates were highest. The onset of leaf growth occurred earlier in Espargal and Mulata than in Galhosa, and both cultivars continued producing new leaves throughout the summer period. The diurnal pattern of water relations in recently expanded leaves indicated that, during midsummer, Galhosa was the only cultivar in which leaf water potential did not fall below the turgor loss point and leaf relative water content remained above 90%. The occurrence of osmotic adjustment in recently expanded leaves of Galhosa was not demonstrated conclusively. However, during the dry season following leaf formation, a seasonal decrease in osmotic potential sufficient to maintain turgor was detected in 1-year-old leaves of Galhosa but not in 1-year-old leaves of the other cultivars. Among cultivars, Galhosa petioles had the widest xylem conduits, which may partly explain why midday leaf water potential in Galhosa never decreased below -2.0 MPa even at the end of the summer drought.

  20. Ineffective erythropoiesis in beta-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin.

    Science.gov (United States)

    Gardenghi, Sara; Marongiu, Maria F; Ramos, Pedro; Guy, Ella; Breda, Laura; Chadburn, Amy; Liu, YiFang; Amariglio, Ninette; Rechavi, Gideon; Rachmilewitz, Eliezer A; Breuer, William; Cabantchik, Z Ioav; Wrighting, Diedra M; Andrews, Nancy C; de Sousa, Maria; Giardina, Patricia J; Grady, Robert W; Rivella, Stefano

    2007-06-01

    Progressive iron overload is the most salient and ultimately fatal complication of beta-thalassemia. However, little is known about the relationship among ineffective erythropoiesis (IE), the role of iron-regulatory genes, and tissue iron distribution in beta-thalassemia. We analyzed tissue iron content and iron-regulatory gene expression in the liver, duodenum, spleen, bone marrow, kidney, and heart of mice up to 1 year old that exhibit levels of iron overload and anemia consistent with both beta-thalassemia intermedia (th3/+) and major (th3/th3). Here we show, for the first time, that tissue and cellular iron distribution are abnormal and different in th3/+ and th3/th3 mice, and that transfusion therapy can rescue mice affected by beta-thalassemia major and modify both the absorption and distribution of iron. Our study reveals that the degree of IE dictates tissue iron distribution and that IE and iron content regulate hepcidin (Hamp1) and other iron-regulatory genes such as Hfe and Cebpa. In young th3/+ and th3/th3 mice, low Hamp1 levels are responsible for increased iron absorption. However, in 1-year-old th3/+ animals, Hamp1 levels rise and it is rather the increase of ferroportin (Fpn1) that sustains iron accumulation, thus revealing a fundamental role of this iron transporter in the iron overload of beta-thalassemia.

  1. 1- and 2-year-olds' expectations about third-party communicative actions.

    Science.gov (United States)

    Thorgrimsson, Gudmundur B; Fawcett, Christine; Liszkowski, Ulf

    2015-05-01

    Infants expect people to direct actions toward objects, and they respond to actions directed to themselves, but do they have expectations about actions directed to third parties? In two experiments, we used eye tracking to investigate 1- and 2-year-olds' expectations about communicative actions addressed to a third party. Experiment 1 presented infants with videos where an adult (the Emitter) either uttered a sentence or produced non-speech sounds. The Emitter was either face-to-face with another adult (the Recipient) or the two were back-to-back. The Recipient did not respond to any of the sounds. We found that 2-, but not 1-year-olds looked quicker and longer at the Recipient following speech than non-speech, suggesting that they expected her to respond to speech. These effects were specific to the face-to-face context. Experiment 2 presented 1-year-olds with similar face-to-face exchanges but modified to engage infants and minimize task demands. The infants looked quicker to the Recipient following speech than non-speech, suggesting that they expected a response to speech. The study suggests that by 1 year of age infants expect communicative actions to be directed at a third-party listener.

  2. Validating indicators of sheep welfare through a consensus of expert opinion.

    Science.gov (United States)

    Phythian, C J; Michalopoulou, E; Jones, P H; Winter, A C; Clarkson, M J; Stubbings, L A; Grove-White, D; Cripps, P J; Duncan, J S

    2011-05-01

    A consensus of expert opinion was used to provide both face and consensual validity to a list of potential indicators of sheep welfare. This approach was used as a first step in the identification of valid welfare indicators for sheep. The consensus methodology of the National Institute of Health, using pre-meeting consultation and focus group discussions, was used to ascertain the consensus opinion of a panel of sheep welfare experts. The Farm Animal Welfare Council's five freedoms were used as a framework to organise a list of current on-farm welfare issues for sheep. The five freedoms were also the welfare criterion used to identify potential on-farm welfare indicators for sheep. As a result, experts identified 193 welfare issues for sheep and lambs managed on farms across England and Wales. Subsequently, a combination of animal- (n = 26), resource- (n = 13) and management- (n = 22) based indicators was suggested for (i) adult rams, (ii) adult ewes (male and female sheep, over 1 year old), (iii) growing lambs (male and female sheep, over 6 weeks to 1 year old) and (iv) young lambs (male and female lambs, 6 weeks old and under). The results from this study could therefore be used to inform the further development of valid methods of assessing the on-farm welfare of sheep.

  3. Retrospective study of mortality in Asiatic lions (Panthera leo persica) in the European breeding population between 2000 and 2014.

    Science.gov (United States)

    Metz, Olivia; Williams, Jonathan; Nielsen, Rikke Kruse; Masters, Nic

    2017-01-01

    Although the European population of Asiatic lions (Panthera leo persica) has been managed under the European Endangered Species Program (EEP) since 1990, little is known about the health status of the population. This study was designed to characterize mortality for this population through examination of the studbook and other records on 392 Asiatic lions living in the EEP between 2000 and 2014. A total of 270 animals died during the period with 80% of them being under 1 year old. The mortality rate for under 1 year olds was 54%, while the odds of survival of cubs within a litter increased if the dam had had litters previously. Survival to reproductive age was 44%. Post-mortem reports were requested and the cause of death was obtained for 133 animals. Trauma inflicted by a conspecific and lack of care were common causes of death (26% and 22%, respectively) and were also responsible for most of the neonatal mortalities. Congenital defects were responsible for 9% of deaths, although the true prevalence is likely underestimated. A common necropsy protocol for all Asiatic lion collections is needed to facilitate future studies. Zoo Biol. 36:66-73, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  4. The essential oil qualitative and quantitative composition in the needles of Pinus sylvestris L. growing along industrial transects

    Energy Technology Data Exchange (ETDEWEB)

    Kupcinskiene, Eugenija [Department of Biology, Vytautas Magnus University, Vileikos 8, LT-44404 Kaunas (Lithuania)], E-mail: e.kupcinskiene@gmail.com; Stikliene, Aida [Department of Ecology, Lithuanian University of Agriculture, Studentu 11, LT-53361 Kaunas, Akademija (Lithuania); Judzentiene, Asta [Institute of Chemistry, A. Gostauto 9, LT-01108 Vilnius (Lithuania)

    2008-10-15

    The aim of this study was to evaluate composition of the essential oils in the needles of Pinus sylvestris growing in the areas affected by a cement factory (CF), and an oil refinery (OR). Volatile components of the needles were analyzed by GC and GC/MS. The most heavily polluted CF stand had significantly higher concentration of {gamma}-Terpinene, Caryophyllene oxide in the current-year needles, while higher concentration of {delta}-3-Carene, {alpha}-Terpinene, {gamma}-Terpinene and Terpinolene was documented for 1-year-old needles. The most heavily polluted OR stand had a significantly higher concentration of Sabinene + {beta}-Pinene, 1-epi-Cubenol in the current-year needles and a significantly higher concentration of Camphene, Sabinene + {beta}-Pinene, Myrcene, {alpha}-Cadinene, 1-epi-Cubenol in the 1-year-old needles than the least polluted site. Along transects an increase in the amount of some diterpenes and a decrease in the components of the shorter chain essential oils was observed. These effects could be at least partially attributed to SO{sub 2}. - Quantities of components of essential oil in the needles of Scots pine growing around two factories are described in relation to pollution.

  5. [Effects levocabastine ophthalmic solution (H1 receptor antagonist) on symptoms of vernal conjunctivitis. A prospective, randomized double-blind study].

    Science.gov (United States)

    Graue, E

    1994-01-01

    A double blind, prospective and randomized study was carried out in forty patients with clinical diagnosis of vernal conjunctivitis and eosinophilia in conjunctival scrapings. They were divided in two randomized groups of 20 patients each. One of the groups received levocabastine ophthalmic solution and the other saline solution drops. The mean age of the study group was 9.1 years old with a vernal conjunctivitis history of 44 months. The control group mean age was 10.1 years old and a history of vernal conjunctivitis of 48 months prior the enter of the study. One group received levocabastine 0.5 mgrs/ml while the other balanced saline solution, one drop every 12 hours per seven days. The patients evaluated their symptoms through a visual analogic scale (every day). Data collected was analyzed, for the first, third and seventh day, through U-Mann Whitney statistical analysis. Epiphora and photophobia showed a significant improvement. Itching, edema and foreign body sensation showed improvement in the levocabastine group but without statistical significance. Hyperthermia remained the same in both groups studied.

  6. Investigation on 2331 cases of pulled elbow over the last 10 years

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    Takashi Irie

    2014-05-01

    Full Text Available Pulled elbow is a common upper extremity injury in children. We present a retrospective study of 2331 pulled elbow cases examined in our hospital over the last ten years. All pediatric patients with a diagnosis of pulled elbow from January 2002 to December 2011 were retrospectively reviewed according to sex, age, affected arm, recurrence rate, mechanism of injury and treatment outcomes. There is no significant sex difference. The frequency of injury peaked for both boys and girls at 6 months and 2 years of age. The left arm was more affected than the right. The recurrence rate was 14%. In about 50% of cases, the cause of injury was forcible traction to the forearm. Almost all of the splinted patients, caused by severe pain or lack of mobility of the affected limb following reduction, recovered within 2 weeks, but 2 were later diagnosed with a fracture. For infants less than 1 year old, injury can often occur when rolling over. For children 1 year old or older the left arm is more commoly affected, and the frequency of injuries to the left arm increases with age, possibly because the left hand is commonly held by the guardian’s dominant right hand and faster development of muscle strength in the child’s dominant right arm works toward preventing injury to that arm with age.

  7. Consumers’ perception and knowledge of food safety: results of questionnaires accessible on IZSalimenTO website

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    Amaranta Traversa

    2015-04-01

    Full Text Available The present survey was undertaken to investigate consumers’ knowledge of the main foodborne agents and dietary regimen during pregnancy. Data were collected using monthly questionnaires available on IZSalimenTO website between March 2013 and January 2014. Hepatitis A virus questionnaire: 20 respondents (77% recognized berries as foodstuff linked to the outbreak of hepatitis A. The majority correctly indicated as precautionary advice to boil berries before consumption. Botulism questionnaire: 29 respondents (62% indicated pesto as food involved in botulism alert in July 2013. The risk of infant botulism in infant less than 1 year old due to honey consumption is known by 24 respondents (51%. Main foodborne disease questionnaire: the risk of infection by Salmonella after the consumption of foods made with raw eggs is known by the majority (94%; N=17 as well as the treatments to be applied in order to make fresh fish safe from parasites (76%. Pregnancy questionnaire: 20 respondents (74% believed that washing vegetables and fruits with sodium bicarbonate or chlorate solution is able to inactivate Toxoplasma; only 4 (15% reported both raw meat and vegetables washed with sodium bicarbonate as food at risk. Results indicate that all consumers should be trained on behaviour and dietary regimen to be adopted in pregnancy and in infant <1 year old. The website may be considered as a useful tool to assess consumers’ knowledge: both the news section and the contents published may be a source of information and education for consumers on food safety.

  8. Evidence for potential impacts of ozone on Pinus cembra L. at mountain sites in Europe: An overview

    Energy Technology Data Exchange (ETDEWEB)

    Wieser, G. [Division Alpine Timberline Ecophysiology, Bundesamt und Forschungszentrum fuer Wald, Rennweg 1, 6020 Innsbruck (Austria)]. E-mail: gerhard.wieser@uibk.ac.at; Manning, W.J. [Department of Microbiology, University of Massachusetts, Amsherst, MA 01003 (United States); Tausz, M. [Institute of Plant Sciences, Karl-Franzens Universitaet Graz, Schubertstrasse 51, 8010 Graz (Austria); School of Forest and Ecosystem Science, University of Melbourne, Water Street, Creswick Victoria 3363 (Australia); Bytnerowicz, A. [USDA Forest Service, Pacific Southwest Research Station, Riverside (United States)

    2006-01-15

    We summarize what is known about the impact of ozone (O{sub 3}) on Pinus cembra in the timberline ecotone of the central European Alps and the Carpathian Mountains. In the central European Alps exposure to ambient and two-fold ambient O{sub 3} throughout one growing season did neither cause any visible injury nor affect the photosynthetic machinery and biochemical parameters in current to 1-year-old needles. By contrast, in the southern French Alps and in the Carpathians 1-year-old needles of Pinus cembra trees showed visual symptoms similar to those observed in O{sub 3} stressed pine stands in southern California. For the southern French Alps the observed symptoms could clearly be attributed O{sub 3} and differences in O{sub 3} uptake seems to be the likely key factor for explaining the observed decline. For the Carpathians however, other reasons such as drought may not be excluded in eliciting the observed symptoms. Thus, the action of O{sub 3} has always to be evaluated in concert with other environmental impacts, determining the tree's sensitivity to stress. - An overview of ozone effects on Pinus cembra an important European coniferous tree species in the timberline ecotone.

  9. Anatomy and morphometry of the olfactory organ of the wels Silurus glanis L. (Siluridae, Pisces).

    Science.gov (United States)

    Jakubowski, M; Kunysz, E

    1979-01-01

    The anatomical structure of the olfactory organs, nerve tracts and brain was described in Silurus glanis. The changes connected with aging were considered. The olfactory lamellae are thin and tightly set in a rosette. In the 1 year old individuals there are 48...51 lamellae in a single rosette. This number increases gradually with age and in the 9...10 year old welses reaches 150. The surface area of the lamellae of a single rosette also indicates an increase: in the 1 year old specimen it equals 117 mm2, while in the adult individual (5...6 year old)--1040 mm2. This is due to the increase in both the size of each lamella and the number of the lamellae. The obtained results are discussed with regard to other author's data. It has been found that the dynamics of the increase of the surface area of the olfactory epithelium in fish are closely related to the way of life and not to the systematic affiliation of the species.

  10. Impaired fasting blood glucose is associated to cognitive impairment and cerebral atrophy in middle-aged non-human primates

    Science.gov (United States)

    Djelti, Fathia; Dhenain, Marc; Terrien, Jérémy; Picq, Jean-Luc; Hardy, Isabelle; Champeval, Delphine; Perret, Martine; Schenker, Esther; Epelbaum, Jacques; Aujard, Fabienne

    2017-01-01

    Age-associated cognitive impairment is a major health and social issue because of increasing aged population. Cognitive decline is not homogeneous in humans and the determinants leading to differences between subjects are not fully understood. In middle-aged healthy humans, fasting blood glucose levels in the upper normal range are associated with memory impairment and cerebral atrophy. Due to a close evolutional similarity to Man, non-human primates may be useful to investigate the relationships between glucose homeostasis, cognitive deficits and structural brain alterations. In the grey mouse lemur, Microcebus murinus, spatial memory deficits have been associated with age and cerebral atrophy but the origin of these alterations have not been clearly identified. Herein, we showed that, on 28 female grey mouse lemurs (age range 2.4-6.1 years-old), age correlated with impaired fasting blood glucose (rs=0.37) but not with impaired glucose tolerance or insulin resistance. In middle-aged animals (4.1-6.1 years-old), fasting blood glucose was inversely and closely linked with spatial memory performance (rs=0.56) and hippocampus (rs=−0.62) or septum (rs=−0.55) volumes. These findings corroborate observations in humans and further support the grey mouse lemur as a natural model to unravel mechanisms which link impaired glucose homeostasis, brain atrophy and cognitive processes. PMID:28039490

  11. Comparison of aortic intima and inner media in young adult versus aging rats. Stereology in a polarized system.

    Science.gov (United States)

    Guyton, J. R.; Lindsay, K. L.; Dao, D. T.

    1983-01-01

    Age-related ultrastructural changes in the intima and inner media of rat thoracic aorta were examined by new morphometric techniques. Young adult male rats, 10 weeks old, were compared with 1-year-old male rats. The most marked changes were found in the sub-endothelium, which increased in thickness more than five-fold. Basement-membrane-like and granular material accounted for the bulk of this thickening. Certain other structures were increased sevenfold or more in subendothelium. These structures and the volume fractions they occupied in 1-year-old rats were as follows: banded collagen, 4.3%; mononuclear leukocytes, 4.5%; cystic structures, 3.3%; and fibrillar elastin, 1.0%. Changes were also demonstrated in the fenestrae of and at selected depth levels below the innermost, or alternatively the internal, elastic lamina. Collagen increased strikingly within fenestrae and just below the elastic lamina. This was associated with a 28% increase in the thickness of the elastic lamina and a recession of smooth muscle cytoplasm to a deeper position within the first musculoelastic medial layer. The alterations in subendothelial tissues imply an altered basis for mechanical support for aortic endothelium in aging rats. These results mark the successful application of micro-computer-based stereology to a situation of polarized geometry. Images Figure 1 Figure 3 Figure 4 Figure 5 PMID:6846504

  12. Effects of GHRP-2 and Cysteamine Administration on Growth Performance, Somatotropic Axis Hormone and Muscle Protein Deposition in Yaks (Bos grunniens) with Growth Retardation.

    Science.gov (United States)

    Hu, Rui; Wang, Zhisheng; Peng, Quanhui; Zou, Huawei; Wang, Hongze; Yu, Xiaoqiang; Jing, Xiaoping; Wang, Yixin; Cao, Binghai; Bao, Shanke; Zhang, Wenhua; Zhao, Suonan; Ji, Hanzhong; Kong, Xiangying; Niu, Quanxi

    2016-01-01

    The objective of this study was to investigate the effects of growth hormone-releasing peptide-2 (GHRP-2) and cysteamine (CS) administration on growth performance in yaks with growth retardation and try to elucidate its regulatory mechanisms. Trial 1, thirty-six 1-year-old Qinghai high plateau yaks (body weight 38-83.2 kg) were randomly chosen for body weight and jugular blood samples collection. The relationship between body weight and serum GHRH (P growth retardation (average body weight 54.8 ± 8.24 kg) were randomly selected and assigned to negative control group (NG), GHRP-2 injection group (GG) and cysteamine feeding group (CG), with 5 yaks per group. Another five 1-year-old Qinghai high plateau yaks with normal growth performance (average body weight 75.3 ± 2.43 kg) were selected as positive control group (PG). The average daily gain (ADG) of the GG and CG were significantly higher than those in the PG and NG (P muscle (Pmuscle (P muscle (Pmuscle atrophy F-box (Atrogin-1) and muscle ring finger 1 (MuRF1) mRNA (P Growth retardation in yaks was primarily due to somatotropic axis hormones secretion deficiency. Both GHRP-2 and CS administration can accelerate growth performance and GH, IGF-1 secretion in yaks with growth retardation. GHRP-2 enhanced muscle protein deposition mainly by up-regulated the protein synthesis pathways, whereas CS worked mainly by down-regulated the ubiquitin-proteasome pathway.

  13. Between-country comparison of whole-body SAR from personal exposure data in Urban areas.

    Science.gov (United States)

    Joseph, Wout; Frei, Patrizia; Röösli, Martin; Vermeeren, Günter; Bolte, John; Thuróczy, György; Gajšek, Peter; Trček, Tomaž; Mohler, Evelyn; Juhász, Péter; Finta, Viktoria; Martens, Luc

    2012-12-01

    In five countries (Belgium, Switzerland, Slovenia, Hungary, and the Netherlands), personal radio frequency electromagnetic field measurements were performed in different microenvironments such as homes, public transports, or outdoors using the same exposure meters. From the mean personal field exposure levels (excluding mobile phone exposure), whole-body absorption values in a 1-year-old child and adult male model were calculated using a statistical multipath exposure method and compared for the five countries. All mean absorptions (maximal total absorption of 3.4 µW/kg for the child and 1.8 µW/kg for the adult) were well below the International Commission on Non-Ionizing Radiation Protection (ICNIRP) basic restriction of 0.08 W/kg for the general public. Generally, incident field exposure levels were well correlated with whole-body absorptions (SAR(wb) ), although the type of microenvironment, frequency of the signals, and dimensions of the considered phantom modify the relationship between these exposure measures. Exposure to the television and Digital Audio Broadcasting band caused relatively higher SAR(wb) values (up to 65%) for the 1-year-old child than signals at higher frequencies due to the body size-dependent absorption rates. Frequency Modulation (FM) caused relatively higher absorptions (up to 80%) in the adult male.

  14. Influence of Pneumococcal Conjugate Vaccine on Acute Otitis Media with Severe Middle Ear Inflammation: A Retrospective Multicenter Study.

    Science.gov (United States)

    Sugino, Hirotoshi; Tsumura, Shigeru; Kunimoto, Masaru; Noda, Masuhiro; Chikuie, Daisuke; Noda, Chieko; Yamashita, Mariko; Watanabe, Hiroshi; Ishii, Hidemasa; Tashiro, Toru; Iwata, Kazuhiro; Kono, Takashi; Tsumura, Kaoru; Sumiya, Takahiro; Takeno, Sachio; Hirakawa, Katsuhiro

    2015-01-01

    The Japanese guidelines for acute otitis media in children recommend classifying acute otitis media by age, manifestations and local findings, and also recommend myringotomy for moderate-grade cases with severe local findings, severe-grade cases, and treatment-resistant cases. The heptavalent pneumococcal conjugate vaccine was released in Japan in February 2010. In Hiroshima City, public funding allowing free inoculation with this vaccine was initiated from January 2011, and the number of vaccinated individuals has since increased dramatically. This study investigated changes in the number of myringotomies performed to treat acute otitis media during the 5-year period from January 2008 to December 2012 at two hospitals and five clinics in the Asa Area of Hiroshima City, Japan. A total of 3,165 myringotomies for acute otitis media were performed. The rate of procedures per child-year performed in media in 1-year-old infants decreased significantly in the 2 years after the introduction of public funding for heptavalent pneumococcal conjugate vaccine compared to all years before introduction (pmedia in reducing the financial burden of myringotomy. In addition, this vaccine may help prevent acute otitis media with severe middle ear inflammation in 1-year-old infants.

  15. Hepatopatía crónica asociada a fibrosis quística: gasto energético en reposo, factores de riesgo y repercusión en la evolución de la enfermedad Chronic liver disease associated with cystic fibrosis: energy expended at rest, risk factors and impact on the disease's progress

    Directory of Open Access Journals (Sweden)

    S. Tabernero da Veiga

    2004-02-01

    Full Text Available Introducción y objetivos: La fibrosis quística es la enfermedad recesiva más frecuente. Existen diferentes alteraciones hepatobiliares; la más importante es el desarrollo de obstrucción biliar y fibrosis periportal. El objetivo es valorar la influencia de la hepatopatía en el estado nutricional, la evolución de la enfermedad y los factores de riesgo asociados. Ámbito: Unidad de Nutrición del Servicio de Gastroenterología del Hospital Infantil La Paz. Material y métodos: Estudio longitudinal prospectivo con 53 pacientes valorados en tres momentos durante 3 años; al inicio, al año y a los 3 años. Solo 37 se siguieron los 3 años. Se realizan 111 mediciones que incluyen: análisis de la composición corporal, del gasto energético, de la ingesta y de las pérdidas energéticas así como balance nitrogenado. Simultáneamente se realizan pruebas de función respiratoria y se valora la presencia de reagudización respiratoria. Resultados: 37 pacientes, 19 mujeres y 18 varones (edad media 13,04 años ± 3,28. Doce (32,43% fueron diagnosticados de hepatopatía (edad media 12,16 años ± 3,86 DS, 11 varones, 1 mujer de los cuales 1 presentó íleo meconial, 5 eran homocigotos, 5 heterocigotos y los 2 restantes presentaban otras mutaciones. Los hepatópatas presentan parámetros antropométricos mejores o similares que los pacientes sin hepatopatía (p NS. Media del índice de Waterlow en hepatópatas: 93,62% ± 7,87 DS; no hepatópatas: 93,06% ± 10,97 DS (p NS. Media de FEV1 en hepatópatas: 88,81 ± 27,32 DS; no hepatópatas: 75,21 ± 27,92 DS (p Introduction and goals: Cystic fibrosis is the most frequent recessive disease. There are various hepato-biliary alterations, of which the most important is the development of biliary obstruction and periportal fibrosis. The goal is to assess the influence of liver disease on the nutritional status, the progress of the disease and the associated risk factors. Scope: Nutrition Unit of the

  16. Anti-inflammatory and toxicity studies of atranorin extracted from Cladina kalbii Ahti in rodents

    Directory of Open Access Journals (Sweden)

    Marcelia Garcez Dória de Melo

    2011-12-01

    Full Text Available Atranorin (ATR is the main compound from the lichen Cladina kalbii Ahti, which grows in the arid regions of northeastern Brazil. This study was conducted to evaluate the anti-inflammatory and toxicological properties of ATR. To evaluate anti-inflammatory properties, paw edema was induced by injecting 0.1 mL of carrageenan into the subplantar region of the right hind paw of rats, and leukocyte migration was induced by injection of 500 µL of carrageenan into the peritoneal cavity of mice. In addition, we determined ATR cytotoxicity in L929 cells by MTT assay and acute (5 g/kg-single dose and subchronic (50 mg/kg-30 days toxicity tests in Wistar rats. The results showed that ATR (100 mg/kg and 200 mg/kg exhibited significant anti-inflammatory activity (paw edema and leukocyte migration. In the acute toxicity test, the animals showed hypoactivity and lethargy during the initial period (first 6 hours and increase in total protein, total and indirect bilirubin, and alkaline phosphatase after 14 days in ATR-treated male rats. The subchronic toxicity test revealed increases in total protein, globulin, gamma-glutamyl transferase, alkaline phosphatase, and total and direct bilirubin in ATR-treated female rats. Histological analysis revealed no changes in the architecture and morphology of the organs. These results suggest that ATR has significant anti-inflammatory activity, with no significant acute and subchronic toxicity or cytotoxicity.Atranorina (ATR é o principal composto do líquen Cladina kalbii Ahti, que cresce em terras áridas do nordeste brasileiro. Este estudo foi realizado para avaliar as propriedades antiinflamatórias e toxicológicas da ATR. Para avaliar as propriedades antiinflamatórias, o edema de pata foi induzido, administrando-se 0,1 mL de carragenina na região subplantar da pata traseira direita e a migração leucocitária foi induzida pela injeção de 500 µL de carragenina no peritônio. Além disso, determinou-se a

  17. Gangliosideos e a resposta de hipersensibilidade retardada em camundongos

    Directory of Open Access Journals (Sweden)

    EFS MONTERO

    2000-01-01

    Full Text Available Em trabalhos anteriores mostrou-se que os gangliosídeos (GSLs têm um efeito inibitório sobre a proliferação linfocitária e a síntese de IL-2, assim como sobre a reação mista de linfócitos. Neste estudo objetivou-se avaliar o efeito dos GSLs sobre a resposta de hipersensibilidade retardada. Foram utilizados 12 camundongos BALB/c, machos, pesando em média 30 gramas, provenientes do biotério setorial da Disciplina de Parasitologia e mantidos por 5 dias para adaptação no biotério setorial da Disciplina de Técnica Operatória e Cirurgia Experimental da UNIFESP-EPM, recebendo água e ração própria para a espécie. Os animais foram distribuídos em três grupos, de acordo com as doses de GSLs, da seguinte forma: grupo 3mg. kg-1, grupo 9mg. kg-1 e grupo simulado (veículo. Os animais foram tratados, por via intramuscular, nos dias 0 e 4. O parâmetro avaliado foi o edema da pata traseira esquerda no local da inoculação do antígeno. Os animais foram anestesiados com Cetamina (60mg.kg-1 e Xilazina (10mg.kg-1, por via intramuscular, sendo em seguida submetidos à dissecção da veia jugular direita, por onde foram inoculadas 10(6 hemácias de Carneiro no dia 0, para sensibilização. No dia 4 subsequente, os animais foram novamente anestesiados e receberam, por via subcutânea, 10(8 hemácias de Carneiro, num volume de 0,02ml. Foram realizadas medidas do edema da pata traseira com paquímetro 24, 48, 72 e 96 horas após o desafio. Os dados mostraram que após 48h houve um aumento do edema em animais dos grupos simulado e 3mg (médias=2,3 and 2,1mm, respectivamente, e os camundongos do grupo 9mg não apresentaram aumento importante (média=0,1mm. Entretanto, após 72h, o grupo 9mg apresentou aumento de 1,7mm enquanto, os outros grupos não apresentaram mudança significativa no edema da pata (médias=0,2 e 0,8mm, grupos simulado e 3mg, respectivamente comparados aos dados do dia antecedente. Após 96h, todos os grupos apresentaram

  18. Vitamin D Status: A Different Story in the Very Young versus the Very Old Romanian Patients.

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    Adela Chirita-Emandi

    Full Text Available In Romania (latitude 48°15'N to 43°40'N, vitamin D supplementation is common practice mostly in infants 0-1 year old. No published information is available regarding epidemiological data on vitamin D status in the Romanian population for a wide age range and geographical territory. In this context, we aimed to evaluate the seasonal and age variation of vitamin D status in a large Romanian population.6631 individuals from across Romania had performed 7544 vitamin D assessments (2012-2014 in a chain of private laboratories. Vitamin D (25-hydroxyvitamin D2 and 25-hydroxyvitamin D3 was measured using High Performance Liquid Chromatography. Vitamin D levels were classified as severe deficiency100 ng/ml.Male to female ratio was 1:2.9. Age ranged from 0 to 85 years. Mean vitamin D levels increased from April (26.3n g/ml to September (35.6 ng/ml and decreased from October (33.5 ng/ml to March (24.4 ng/ml. Overall 40% had sufficient vitamin D, while the rest were insufficient 33%, deficient 22%, severely deficient 4% and 1% potentially harmful (of them 81% under 1 year old. Males compared to females showed higher percentages of sufficiency (47% vs. 38%. Children 0- 2 years presented the highest percentage of vitamin D sufficiency (77%. Lowest percentages (21% of sufficiency were in people 80-84 years.In Romania, suboptimal vitamin D levels are common (59%, especially in older age, wintertime and in women. Vitamin D supplementation would be most warranted from January to April in the Romanian population. 25-hydroxyvitamin D levels > 100 ng/ml were relatively prevalent in children 0-1 year old (17.3%. This was attributed to supplementation errors and the fact that high-risk individuals were more likely to visit for medical check-up. Nonetheless, it stresses the need to increase awareness of the importance of preventing Vitamin D supplementation administration errors in the young.

  19. Changes in phytochemical synthesis, chalcone synthase activity and pharmaceutical qualities of sabah snake grass (Clinacanthus nutans L.) in relation to plant age.

    Science.gov (United States)

    Ghasemzadeh, Ali; Nasiri, Alireza; Jaafar, Hawa Z E; Baghdadi, Ali; Ahmad, Izham

    2014-10-30

    In the current study, changes in secondary metabolite synthesis and the pharmaceutical quality of sabah snake grass leaves and buds were considered in relation to plant age (1 month, 6 months, and 1 year old). The activity of the enzyme chalcone synthase (CHS, EC 2.3.1.74) was measured, as it is a key enzyme for flavonoid production. Significant differences in total flavonoid (TF) production were observed between the three plant growth periods and the different plant parts. The highest contents of TF (6.32 mg/g dry weight [DW]) and total phenolic (TP) (18.21 mg/g DW) were recorded in 6-month-old buds. Among the flavonoids isolated in this study the most important ones based on concentration were from high to low as follows: catechin > quercetin > kaempferol > luteolin. Production of phenolic acids increased from 1 to 6 months, but after 6 months up to 1 year of age, they decreased significantly. The highest contents of caffeic acid (0.307 mg/g DW) and gallic acid (5.96 mg/g DW) were recorded in 1-year and 6-month-old buds, respectively. The lowest and highest activity of CHS was recorded in 1-month and 6-month-old buds with values of 3.6 and 9.5 nkat/mg protein, respectively. These results indicate that the increment in flavonoids and phenolic acids in 6-month-old buds can be attributed to an increase in CHS activity. The highest 1,1-diphenyl-2-picrylhydrazyl (DPPH) activity was observed in the extract of 1-year-old buds followed by 6-month-old buds, with 50% of free radical scavenging (IC50) values of 64.6 and 73.5 µg/mL, respectively. Interestingly, a ferric reducing antioxidant power (FRAP) assay showed a higher activity in 6-month-old buds (488 μM of Fe(II)/g) than in 1-year-old buds (453 μM of Fe(II)/g), in contrast to the DPPH result. Significant correlations (p < 0.05) were observed between CHS enzyme activity and FRAP activity, TF, catechin, and kaempferol content. Extracts of 6-month-old bud exhibited a significant in vitro anticancer activity against

  20. Changes in Phytochemical Synthesis, Chalcone Synthase Activity and Pharmaceutical Qualities of Sabah Snake Grass (Clinacanthus nutans L. in Relation to Plant Age

    Directory of Open Access Journals (Sweden)

    Ali Ghasemzadeh

    2014-10-01

    Full Text Available In the current study, changes in secondary metabolite synthesis and the pharmaceutical quality of sabah snake grass leaves and buds were considered in relation to plant age (1 month, 6 months, and 1 year old. The activity of the enzyme chalcone synthase (CHS, EC 2.3.1.74 was measured, as it is a key enzyme for flavonoid production. Significant differences in total flavonoid (TF production were observed between the three plant growth periods and the different plant parts. The highest contents of TF (6.32 mg/g dry weight [DW] and total phenolic (TP (18.21 mg/g DW were recorded in 6-month-old buds. Among the flavonoids isolated in this study the most important ones based on concentration were from high to low as follows: catechin > quercetin > kaempferol > luteolin. Production of phenolic acids increased from 1 to 6 months, but after 6 months up to 1 year of age, they decreased significantly. The highest contents of caffeic acid (0.307 mg/g DW and gallic acid (5.96 mg/g DW were recorded in 1-year and 6-month-old buds, respectively. The lowest and highest activity of CHS was recorded in 1-month and 6-month-old buds with values of 3.6 and 9.5 nkat/mg protein, respectively. These results indicate that the increment in flavonoids and phenolic acids in 6-month-old buds can be attributed to an increase in CHS activity. The highest 1,1-diphenyl-2-picrylhydrazyl (DPPH activity was observed in the extract of 1-year-old buds followed by 6-month-old buds, with 50% of free radical scavenging (IC50 values of 64.6 and 73.5 µg/mL, respectively. Interestingly, a ferric reducing antioxidant power (FRAP assay showed a higher activity in 6-month-old buds (488 μM of Fe(II/g than in 1-year-old buds (453 μM of Fe(II/g, in contrast to the DPPH result. Significant correlations (p < 0.05 were observed between CHS enzyme activity and FRAP activity, TF, catechin, and kaempferol content. Extracts of 6-month-old bud exhibited a significant in vitro anticancer activity

  1. Effects of GHRP-2 and Cysteamine Administration on Growth Performance, Somatotropic Axis Hormone and Muscle Protein Deposition in Yaks (Bos grunniens) with Growth Retardation

    Science.gov (United States)

    Hu, Rui; Wang, Zhisheng; Peng, Quanhui; Zou, Huawei; Wang, Hongze; Yu, Xiaoqiang; Jing, Xiaoping; Wang, Yixin; Cao, Binghai; Bao, Shanke; Zhang, Wenhua; Zhao, Suonan; Ji, Hanzhong; Kong, Xiangying; Niu, Quanxi

    2016-01-01

    The objective of this study was to investigate the effects of growth hormone-releasing peptide-2 (GHRP-2) and cysteamine (CS) administration on growth performance in yaks with growth retardation and try to elucidate its regulatory mechanisms. Trial 1, thirty-six 1-year-old Qinghai high plateau yaks (body weight 38–83.2 kg) were randomly chosen for body weight and jugular blood samples collection. The relationship between body weight and serum GHRH (P < 0.05, R = 0.45), GH (P < 0.05, R = 0.47), IGF-1 (P < 0.05, R = 0.62) was significantly correlated in yaks colonies with lighter body weights. Trial 2, fifteen 1-year-old Qinghai high plateau yaks with growth retardation (average body weight 54.8 ± 8.24 kg) were randomly selected and assigned to negative control group (NG), GHRP-2 injection group (GG) and cysteamine feeding group (CG), with 5 yaks per group. Another five 1-year-old Qinghai high plateau yaks with normal growth performance (average body weight 75.3 ± 2.43 kg) were selected as positive control group (PG). The average daily gain (ADG) of the GG and CG were significantly higher than those in the PG and NG (P < 0.05). Both GHRP-2 and CS administration significantly enhanced the myofiber diameter and area of skeletal muscle (P<0.05). GHRP-2 significantly enhanced the serum GH and IGF-1 levels (P < 0.05), and up-regulated GHR, IGF-1 and IGF-1R mRNA expression in the liver and skeletal muscle (P < 0.05), enhanced the mRNA expression of PI3K, AKt and mTOR in the skeletal muscle (P<0.05). CS significantly reduced the serum SS levels and the hypothalamus SS mRNA expression (P < 0.05), and enhanced GHR and IGF-1 mRNA expression in the liver (P < 0.05), decreased the mRNA expression of muscle atrophy F-box (Atrogin-1) and muscle ring finger 1 (MuRF1) mRNA (P < 0.05). Conclusions: Growth retardation in yaks was primarily due to somatotropic axis hormones secretion deficiency. Both GHRP-2 and CS administration can accelerate growth performance and GH, IGF-1

  2. Atrial – Ventricular Septal Defect

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    T Panagiotopoulos

    2009-05-01

    Full Text Available Atrial and ventricular septal defect constitute the most common congenital heart disease.Aim: Τhe aim of the present retrospective study was to record data and factors that affect atrial and ventricular septal defect.Method and material: The sample study included patients of both sexes who were hospitalized with diagnosis atrial and ventricular septal defect in a Cardiac Surgery hospital of Athens. A specially constructed printed form was used for data collection, where were recorded the demographic and personal variables, the pathological, surgical, cardiology and obstetric history, the habits of adults, as well as the personal characteristics of mothers. Analysis of data was performed by descriptive statistical analysis.Results: The sample study consisted of 101 individuals with diagnosis atrial or ventricular Septal Defect, of which 40% were boys and 60% girls. The 70% of the sample study suffered from atrial Septal Defect and the 30% suffered from ventricular Septal Defect. Regarding age, 12% of the sample study was 0-1 years old, 35% was >1 years old, 8% was >12-18 years old and 45% over than 18 years old. Regarding educational status of the adult participants, 9% was of 0-6 years education, 22%>6 -12 years, 13%>12 years. 14% of the adult paticipants smoked, 4% consumed alcohol and 5% smoked in conjunction with alcohol. In terms of the obstetric history of the sample studied, 32% of the cases had normal birth, 4% had a twin birth and 1% had a triplet one. According to the variables related to mothers, the mean age of the mother was 30 years and 3 months, 10% were smokers at pregnancy and 3% used chemical substance and mainly hair color. Also, the results of the present study showed that individuals of 12-18 and >18 years old did not suffer from ventricular Septal Defect, whereas the infants 0-1 years old did not suffer from Atrial Septal Defect. The mean value of age at the admission in intensive care unit was 7 months (12% for the infants

  3. CO2 uptake of Opuntia ficus-indica (L. Mill. whole trees and single cladodes, in relation to plant water status and cladode age

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    Giorgia Liguori

    2013-02-01

    Full Text Available Most of net photosynthesis determinations in Opuntia ficus-indica come from measurements on individual cladodes. However, they have limitations when used to scale up to whole canopy gas exchange, because a large variability of carbon assimilation may occur within the canopy, due to, among others, differences in cladode age and intercepted radiation or individual cladode response to abiotic stresses. The aim of this work was to evaluate the application of open gas exchange chambers, simultaneously applied around the whole canopy, to measure net CO2 uptake, continuously over a 24 h period, in single Opuntia ficus-indica (L. Mill. potted trees and in relation with their water status. Net CO2 uptake was also measured for single cladodes differentiated by age. O. ficus-indica trees continued their photosynthetic activity 60 days after the irrigation was stopped, when soil water content was lower than 5%. At this stage, current-year and 1-year-old cladodes had become flaccid but still the daily net CO2 uptake of non-irrigated trees kept the same rate than at the beginning of the experiment, while watered trees had doubled their net CO2 uptake. The highest instantaneous rates and total daily net CO2 uptake for both well-watered and non-irrigated trees occurred 60 days after the onset of the dry period, when maximal instantaneous rates were 11.1 in well-watered trees and 8.4 mol m–2 s–1 in non-irrigated trees. During the drought period, the chlorenchyma fresh weight decreased by 45% and 30%, in 1- and 2-yearold drought cladodes respectively, and marginally increased in currentyear ones (+20%. Net CO2 uptake for 1-year-old and 2-year-old cladodes changed only at highest photosynthetic photon flux density and temperatures, and average seasonal net CO2 uptake of 2-year-old cladodes was 15% lower than for 1-year-old ones. Whole-tree gas exchange measurements applied for the first time to O. ficus-indica indicated that whole cactus pear trees maintain

  4. Validação de metodologia espectrofotométrica para quantificação dos flavonóides de Bauhinia cheilantha (Bongard Steudel Validation of spectrophotometric methodology for quantify flavonoid content in Bauhinia cheilantha (Bongard Steudel

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    Tadeu José da Silva Peixoto Sobrinho

    2008-12-01

    Full Text Available Os laboratórios de fitoterápicos necessitam de metodologias que assegurem o controle de qualidade de seus produtos quando os mesmos não constam em farmacopéias ou monografias oficiais. Baseando-se neste fato, o presente estudo visou validar uma metodologia analítica para quantificação de flavonóides contidos nos extratos da pata-de-vaca (Bauhinia cheilantha [Bongard] Steudel, através de espectrofotometria no visível, como equivalentes de Rutina (µg/mL. Todos os parâmetros exigidos pela ANVISA foram avaliados. No teste de especificidade, observou-se a existência de pico máximo a 420 nm. O método foi considerado linear e com alta sensibilidade de quantificação (2,51 µg/mL. O método também mostrou-se robusto e com elevada recuperação (98,36%. Os resultados obtidos para repetibilidade (intra-corrida, precisão intermediária (inter-corridas e reprodutibilidade certificaram a precisão do método com valores entre 0,31 e 3,58%, sendo também considerado exato (95,71-105,50%. Com este estudo, o método proposto foi considerado específico, preciso, reprodutível, exato, de baixo custo e fácil execução.Phytotherapeutic laboratories require access to methodologies that guarantee quality control for their products when these items are not already registered in pharmacopeias or official monographs. As such, the present study sought to validate analytical methodologies for quantifying natural flavonoids contained in extracts of "pata-de-vaca" (Bauhinia cheilantha [Bong.] Steudel using visible light spectrophotometry and a rutin standard (µg/ml. All of the parameters required by ANVISA were evaluated. The specificity test revealed a maximum absorption peak at 420 nm. The methodology was considered linear and of high quantification sensitivity (2.51 µg/ml. The methodology also proved to be robust, and had high recovery levels (98.36%. The results obtained for repeatability, intermediate precision (intra- and inter-day, and

  5. Avaliação funcional da nocicepção do joelho de ratos tratada com laser de baixa potência e natação

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    Gladson Ricardo Flor Bertolini

    2011-02-01

    Full Text Available O objetivo deste estudo foi avaliar e comparar os efeitos do laser de baixa potência e da natação forçada em modelo de nocicepção articular, de ratos Wistar, avaliando a dor de forma funcional, pelo tempo de elevação da pata (TEP durante marcha em cilindro metálico. Foram utilizados 32 ratos Wistar, divididos em quatro grupos: GC - animais submetidos à indução de nocicepção no joelho direito e não tratados; GL - nocicepção e tratados com laser de baixa potência 670nm, 8J/cm²; GN - nocicepção e natação por 10 minutos em água a 30-32ºC; GNL - nocicepção e tratados com natação e laser. Para realizar a nocicepção foi injetado, no espaço tibiofemoral medial direito, 50µL de formalina 5%. A avaliação funcional da dor foi realizada com o teste de incapacidade funcional, que avalia o tempo de pata no ar (TEP da marcha durante um minuto sobre um cilindro metálico, as avaliações ocorreram antes da indução da nocicepção (AV1, após 15 (AV2 e 30 minutos (AV3 da mesma, sendo que após a AV2, ocorreram os protocolos de tratamento. Os resultados mostraram que o grupo laser foi o único a apresentar restauração dos valores na AV3, comparando com AV1. GN foi o único a não apresentar redução ao comparar AV3 com AV2. Conclui-se que, pela avaliação funcional, o laser de baixa potência apresentou efeitos analgésicos, enquanto a natação produziu aumento do quadro de dor, o qual foi parcialmente revertido com o uso do laser associado

  6. Surto de varíola murina em camundongos suíços em biotério: Relato de caso An outbreak of mousepox in swiss mice in a laboratory animal facility: Case report

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    S. Diniz

    2001-04-01

    Full Text Available Duzentos camundongos suíços foram alojados em um biotério com instalações e condições de manejo adequadas para uma criação de animais convencionais sadios. Após 14 dias de alojamento, dois animais tiveram morte súbita, e em 74 animais (37% foram observados sintomas clínicos como edema da face e das patas. Uma semana após foram observadas lesões generalizadas na pele ou somente no dorso, na face, no focinho e nas patas, nódulos na cauda, e em cinco animais conjuntivite. A necropsia de 10 camundongos indicou alterações como hepatomegalia, esplenomegalia e hiperplasia dos gânglios. Amostras do fígado, baço e de lesões da cauda foram inoculadas em membrana corioalantóide (MCA de ovos embrionados de galinha. Após 72 horas foram detectadas lesões necróticas típicas denominadas "pocks". As MCAs foram maceradas e inoculadas em culturas de células Vero e detectado efeito citopático após 72 horas. O diagnóstico da varíola murina foi baseado nos sinais clínicos, lesões, cultivo e na identificação do vírus.Two hundred Swiss mice were housed following the requirements to produce healthy laboratory animals. After 14 days two mice had an acute lethal infection and one week later 74 animals (37% presented multiple skin lesions some of them associated with conjunctivitis. Necropsy of 10 mice with clinical signs (swelling of feet and facial area revealed alterations in the spleen, liver and lymphonodes. Samples of hepatic and splenic tissues and of tail lesions were inoculated on chorioallantoic membrane (MCA of embrionated chicken eggs and pocks lesions were detected. The MCAs were grinded and inoculated in Vero cell cultures and the cytophatic effect was detected after 72 hours. Diagnosis of mousepox was based on clinical signs, lesions and virus isolation and identification.

  7. O papel do esteroide anabolizante sobre a hipertrofia e força muscular em treinamentos de resistência aeróbia e de força

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    Everton Crivoi do Carmo

    2011-06-01

    Full Text Available INTRODUÇÃO: Os efeitos dos esteroides anabolizantes (EA sobre a massa muscular e força são controversos e dependentes do treinamento realizado e das fibras musculares recrutadas. Com isso, o objetivo deste estudo foi avaliar os efeitos da associação de EA ao treinamento de força ou aeróbio sobre a hipertrofia e força muscular. MÉTODOS: Ratos Wistar (42 foram divididos em seis grupos: sedentário (SC, n = 7, sedentário anabolizante (SA, n = 7, treinado natação controle (TNC, n = 7, treinado natação anabolizante (TNA, n = 7, treinado força controle (TFC, n = 7 e treinado força anabolizante (TFA, n = 7. O EA foi administrado duas vezes por semana (10mg/kg/semana. Os protocolos de treinamento foram realizados durante 10 semanas, cinco sessões semanais. Foram avaliadas a hipertrofia dos músculos sóleo, plantar e gastrocnêmio (massa muscular corrigida pelo comprimento da tíbia, a proteína total muscular (Bradford e a força muscular em patas traseiras (testes de resistência à inclinação. RESULTADOS: Não foram observadas diferenças significantes na hipertrofia do músculo sóleo. Os grupos TFC e TFA apresentaram, respectivamente, hipertrofia de 18% e 31% no músculo plantar comparado ao grupo SC. A hipertrofia foi 13% maior no grupo TFA em relação ao grupo TFC. Resultados semelhantes foram encontrados no músculo gastrocnêmio. Os grupos TFC e TFA apresentaram significantes aumentos na quantidade total de proteína nos músculos plantares, sendo essa mais pronunciada no grupo TFA e positivamente correlaciona a hipertrofia muscular. Observamos aumento de força nas patas traseiras nos grupos TCF e TAF. CONCLUSÃO: A administração de EA ou sua associação ao treinamento aeróbio não aumenta a massa muscular e força. Porém, à associação ao treinamento de força leva a maior hipertrofia muscular em fibras glicolíticas. Portanto, o tipo de treinamento físico, recrutamento muscular e características das fibras

  8. Efeito do tratamento com algumas vitaminas B na potencialização do efeito antiinflamatório e antinociceptivo do diclofenaco e da talidomida

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    N. M.K. NAKAEMA

    2009-01-01

    Full Text Available

    Mostrou-se que o pré-tratamento com as vitaminas tiamina[B1], piridoxina[B6] e cianocobalamina [B12], isoladas ou administradas conjuntamente, não inibiu o edema de pata produzido pela carragenina em ratos, nem as contorções abdominais produzidas pelo ácido acético em camundongos. Por outro lado, o diclofenaco [25 ou 50mg/kg] ou talidomida [45mg/kg] inibiram o edema de pata em ratos, e a associação das três vitaminas à estas drogas, mas não as vitaminas administradas isoladamente, potencializou os efeitos do diclofenaco [25 ou 50mg/kg] no tempo de quatro horas e a talidomida [45mg/kg], nos tempos de duas, três e quatro horas após a carragenina. As contorções abdominais em camundongos foram inibidas pelas doses de 25 ou 50mg/ kg de diclofenaco. A associação das três vitaminas ou apenas da cianocobalamina, potencializou as duas doses do diclofenaco utilizadas. As contorções abdominais foram inibidas também pela talidomida [45mg/kg] e a associação das três vitaminas, ou cada uma das vitaminas administradas isoladamente, foram capazes de potencializar os efeitos da talidomida. É provável que a diferença no mecanismo de ação destas drogas seja responsável por esta diferença dos efeitos das vitaminas. O presente estudo preconiza o uso de antiinflamatórios, combinados com as vitaminas tiamina[B1], piridoxina[B6] e cianocobalamina [B12], em doenças crônicas, diminuindo assim a dose destas drogas e seus efeitos colaterais. Palavras-chave: Diclofenaco; talidomida; contorção abdominal; piridoxina; cianocobalamina; tiamina.

  9. A síndrome anserina Anserine syndrome

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    Milton Helfenstein Jr

    2010-06-01

    Full Text Available Dor no joelho é uma condição comum na clínica diária e a patologia anserina, também conhecida como pata de ganso, tem sido considerada uma das principais causas. O diagnóstico tem sido realizado de maneira eminentemente clínica, o que tem gerado equívocos. Os pacientes queixam-se tipicamente de dor na parte medial do joelho, com sensibilidade na porção ínferomedial. Estudos de imagem têm sido realizados para esclarecer se tais pacientes possuem bursite, tendinite ou ambos os distúrbios na região conhecida como pata de ganso. Entretanto, o defeito estrutural responsável pelos sintomas permanece desconhecido, motivo pelo qual preferimos intitular como "Síndrome Anserina". O diabetes mellitus é um fator predisponente bem reconhecido. O sobrepeso e a osteoartrite de joelho parecem ser fatores adicionais de risco, contudo, seus papéis na gênese da moléstia ainda não são bem entendidos. O tratamento atual inclui anti-inflamatório, fisioterapia e infiltração de corticoide, com evolução muito variável, que oscila entre 10 dias e 36 meses. A falta de conhecimento sobre a etiofisiopatologia e dados epidemiológicos exige futuros estudos para esse frequente e intrigante distúrbio.Knee pain is a common complaint in clinical practice, and pes anserinus tendino-bursitis syndrome (PATB has been frequently diagnosed based only on clinical features that may cause equivocal interpretations. Patients complain of characteristic spontaneous medial knee pain with tenderness in the inferomedial aspect of the joint. Studies with different imaging modalities have been undertaken during the last years to identify whether these patients suffer from bursitis, tendinitis, or both. Nevertheless, little is known regarding the structural defect responsible for this disturbance. Due to these problems and some controversies, we suggest the term "anserine syndrome" for this condition. Diabetes Mellitus is a known predisposing factor for this syndrome

  10. Efeito analgésico e anti-inflamatório do extrato aquoso das folhas de trevo-roxo (Scutellaria agrestis A. St.-Hil. ex Benth. - Lamiaceae em roedores

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    A.B. Oliveira

    2014-06-01

    Full Text Available Scutellaria agrestis é utilizada por comunidades ribeirinhas do Amazonas principalmente para o tratamento de otites por via tópica utilizando-se o extrato bruto obtido por maceração. O presente trabalho visou investigar preliminarmente o perfil fitoquímico, a segurança toxicológica e as ações analgésica, anti-inflamatória e antiedematogência do extrato aquoso das folhas de S. agrestis. Foram coletados 80 indivíduos da espécie no horto medicinal da Universidade Nilton Lins, Manaus, Brasil. O perfil fitoquímico foi obtido por meio de prospecção da droga vegetal para heterosídeos cianogênicos, terpenos, compostos fenólicos e alcaloides. A toxicologia foi avaliada pelo teste de toxicidade aguda. As atividades analgésicas/ anti-inflamatórias foram analisadas por meio dos testes de formalina em camundongos e a atividade antiedematogência, pelo teste de edema de pata em ratos. Os metabólitos detectados foram fenóis (taninos hidrolisáveis, cumarinas e várias classes de flavonoides e terpenos (esteroides livres, saponinas. Não foi possível estabelecer DL50, haja visto que o extrato não provocou a morte de nenhum animal durante o teste de toxicidade aguda, provavelmente devido à ausência de heterosídeos cianogênicos na sua composição. Apesar de não provocar morte, considerou-se que o extrato apresenta uma discreta toxicidade, uma vez que foi observada a ocorrência de espasmos na primeira hora de observação dos animais. O extrato apresentou ainda efeito analgésico e anti-inflamatório significativo nas doses de 30, 100 e 300 mg/kg pelo teste da formalina, sendo o resultado na maior dose equivalente ao obtido com a droga padrão (fentanil. No entanto, não observamos efeito antiedematogênico nas doses testadas durante as 5 horas de registro do edema de pata. Os resultados obtidos nesta pesquisa conferem base científica preliminar quanto à segurança e ao efeito analgésico e antiinflamatório da droga vegetal, o

  11. Prevalence of Colacium vesiculosum (Colaciales: Euglenophyceae on planktonic crustaceans in a subtropical shallow lake of Argentina

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    Yolanda Zalocar

    2011-09-01

    locomoción y alimentación tienen mayor probabilidad de encuentro con los epibiontes: antenas y patas toráxicas en copépodos, patas toráxicas y postabdomen en cladóceros. Valores similares en la tasa de filtración entre individuos infestados y no infestados de N. spiniger y la constante prevalencia (<40% del alga epibionte sugieren que C. vesiculosum no condicionaría la vida de los microcrustáceos planctónicos del lago Paiva.

  12. Identificación de individuos de jaguares (Panthera onca y pumas (Puma concolor a partir de morfometría de sus huellas (Carnivora: Felidae

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    Emiliana Isasi-Catalá

    2008-12-01

    Full Text Available Estimar la abundancia de felinos resulta particular-mente difícil o, incluso imposible, debido a su comportamiento críptico y sus amplios requerimiento espaciales. Las técnicas disponibles para estimar abundancia son costosas y poco eficientes, por lo que es necesario proponer métodos alternativos. El objetivo de este trabajo fue evaluar la capacidad de identificación de individuos utilizando el análisis morfométrico de huellas en yaguares y pumas. Para ello, se dibujaron huellas de cinco yaguares y cuatro pumas, registrándose el tipo de pata que dio origen a la huella y el sustrato. Para cada huella se tomaron 16 mediciones morfológicas de ángulos, largos, anchos y áreas. Las variables de largos, anchos y áreas fueron analizadas con un Análisis de Componentes Principales (ACP y sustituidas por el primer componente principal (más del 70 % de la varianza en todos los casos. Se evaluó el efecto del sustrato y del tipo de pata a partir de pruebas t-pareadas, encontrándose diferencias entre huellas del mismo individuo dibujadas a partir de arena o tierra (t-pareadas p Identification of individual jaguars (Panthera onca and pumas (Puma concolor based on footprint morphometry (Carnivora: Felidae. Estimating feline abundance becomes particularly difficult, sometimes impossible, due to their elusive behavior and extensive space requirements. Available techniques are expensive and/or poorly efficient, therefore alternative methods are needed. The objective of this study was to assess the possibility of identifying individual jaguars and pumas based on morphometric analyses of their tracks. The footprints of five jaguars and four pumas were drawn and the foot (hind or fore foot, left or right foot and the substrate were recorded. We took 16 measures from each footprint including lengths, widths, areas and angles. Variables were analyzed by using Principal Component Analysis (PCA and substituted by the first Principal Component (PC (> 70

  13. Uso empírico de plantas medicinais para tratamento de diabetes Empirical use of medicinal plants for diabetes treatment

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    M.M Santos

    2012-01-01

    Full Text Available Diabetes é alvo interessante para a busca de novos métodos de tratamento com a possibilidade de uso de várias espécies de plantas medicinais. Este trabalho objetivou descrever a prevalência do uso de plantas medicinais consideradas hipoglicemiantes por pacientes diabéticos em Vitória de Santo Antão. O estudo foi do tipo descritivo transversal realizado com 158 pacientes diabéticos atendidos pelo programa HIPERDIA nos PSF's da cidade entre julho de 2009 a maio de 2010, com a coleta de dados realizada por meio de formulário estruturado. Entre os entrevistados, 36% relatavam uso de plantas medicinais consideradas hipoglicemiantes. Foram citadas 35 plantas diferentes pertencentes à 24 famílias, sendo as mais freqüentes: Asteraceae (12,5% e Myrtaceae (9,37%. A planta medicinal mais prevalente foi a pata de vaca (Bauhinia sp, com 16,8%, seguida por azeitona roxa (Syzygium jambolanum DC. e insulina (Cissus sicyoides L.. A maioria dos indivíduos (58% cultivava a planta medicinal que usavam e, entre aqueles que adquiriam, a principal fonte foi a de raizeiros (28,16%.Diabetes is an attractive target to search for new methods of treatment, with the possibility of using several medicinal plant species. This study aimed to describe the prevalence of the use of medicinal plants considered hypoglycemic for diabetic patients from Vitoria de Santo Antão-Pernambuco State, Brazil. This was a transversal descriptive study conducted with 158 diabetic patients enrolled in the program HIPERDIA at the PSF's of this city, between July 2009 and May 2010 with data collected by means of structured form. Among interviewees, 36% reported the use of medicinal plants considered hypoglycemic. A total of 35 different plants belonging to 24 families were cited and the most frequent species were: Asteraceae (12.5% and Myrtaceae (9.37%. The most prevalent medicinal plant was "pata-de-vaca" (Bahuinia sp., with 16.8%, followed by "azeitona roxa" (Syzygium jambolanum DC

  14. Efeitos de concentrações crescentes de lidocaína hiperbárica, administradas no espaço subaracnóideo, sobre a medula espinhal e as meninges: estudo experimental em cães Efectos de concentraciones crecientes de lidocaína hiperbara, administradas en el espacio subaracnoideo, sobre la médula espinal y las meninges: estudio experimental en perros Effects of increasing spinal hyperbaric lidocaine concentrations on spinal cord and meninges: experimental study in dogs

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    Silvânia R.O. Pires

    2006-06-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Ainda não está bem estabelecida a concentração de lidocaína que é potencialmente capaz de determinar lesão no tecido nervoso. O objetivo desta pesquisa foi estudar os efeitos sobre a medula espinhal e as meninges, de concentrações crescentes de lidocaína administrada por via subaracnóidea, em injeção única através de agulha de Quincke. MÉTODO: Após a aprovação da Comissão de Ética em Experimentação Animal, 40 cães adultos foram anestesiados com fentanil e etomidato e submetidos a punção subaracnóidea com agulha de Quincke 22G 21/2 para introdução de 1 mL, em 10 segundos, de solução glicosada a 7,5% - Grupo 1; lidocaína a 5% em solução glicosada a 7,5% - Grupo 2; lidocaína a 7,5% em solução glicosada a 7,5% - Grupo 3; lidocaína a 10% em solução glicosada a 7,5% - Grupo 4. Após a recuperação da anestesia venosa, foram observados, no período em que os animais estavam em vigência do bloqueio subaracnóideo, a presença de bloqueio motor, o tônus do esfíncter anal (normal ou relaxado e o nível de bloqueio sensitivo nos diferentes dermátomos das regiões cervical, torácica, lombar e sacral. Os animais permaneceram em cativeiro por 72 horas. Foram avaliados o tônus do esfíncter anal, a motricidade das patas posteriores, a sensibilidade dolorosa nas patas anteriores e posteriores e nos dermátomos sacrais, lombares e torácicos. Após serem sacrificados por eletrocussão sob anestesia, foram retiradas porções lombar e sacral da medula espinhal e das meninges para exame histológico por microscopia óptica. RESULTADOS: Nenhum animal dos Grupos 1 e 2 apresentou lesões clínicas ou histológicas. Três animais do Grupo 3 apresentaram alterações motoras nas patas posteriores e relaxamento do esfíncter anal. Nestes, foram observados focos de necrose na região posterior (dois cães e necrose em faixa em toda a superfície medular (um cão. Em um outro animal deste grupo, no

  15. Descripción de la morfología externa por microscopia de luz y electrónica de barrido de Megninia ginglymura, Megnin, 1877 en faisán de collar (Phasianus torquatus, en un criadero de Corrientes, Argentina

    Directory of Open Access Journals (Sweden)

    A. Santa Cruz ; M. C. Agüero ; J. A. González; J.A Comolli ; D. Cayo; J. P. Roux.-

    2008-09-01

    Full Text Available El objetivo de este trabajo es reportar el primer hallazgo de Megninia ginglymura, Megnin, 1877 (Arthropoda, Arachnida, Acari, Astigmata, Analgidae, en faisán de collar (Phasianus torquatus y describir algunos caracteres morfológicos externos a través imágenes obtenidas con microscopios de luz y microscopio electrónico de barrido. La investigación se llevó a cabo en un criadero ubicado en la localidad del Ingenio Santa Ana de la ciudad de Corrientes, Latitud 27º 26´ 01, Longitud 58º 37´ 21. Del plantel de 500 faisanes de collar (Phasianus torquatus se examinaron 15 (10 animales jóvenes y 5 adultos que presentaban lesiones principalmente en la cabeza, cuello y dorso, y se tomaron muestras de plumas de las zonas afectadas. Se colectaron ácaros que fueron montados entre porta y cubreobjetos con líquido de Hoyer’s, para su posterior clasificación sistemática; los ejemplares destinados a microscopía electrónica de barrido se conservaron en Glutaraldehído al 3%. Los especimenes presentaron pronunciado dimorfismo sexual, en el macho se observó el tercer par de patas más desarrollada y la presencia de lóbulos posteriores con ventosas copulatrices. En las hembras se advirtió lasimilitud de todas las patas, con el borde posterior de su cuerposemiredondeado. Las lesiones observadas fueron pérdida y corte deplumas en las alas, dorso y en la mayor parte del cuerpo. Estas lesiones corresponden a la acción parasitaria de Megninia ginglymura. Constituye el primer hallazgo en faisán de collar (Phasianus torquatus y la primera descripción de algunos aspectos morfológicos externos de Megninia ginglymura, Megnin, 1877 (Arthropoda, Arachnida, Acari, Astigmata, Analgidae, que se realiza mediante el uso de microscopio de luz y microscopio electrónico de barrido en la Argentina.

  16. Efeitos de um minuto e dez minutos de deambulação em ratos com artrite induzida por adjuvante completo de Freund sobre os sintomas de dor e edema

    Directory of Open Access Journals (Sweden)

    Raquel Pinheiro Gomes

    2014-04-01

    Full Text Available Este estudo avaliou o efeito de dois protocolos de exercício na nocicepção, edema e migração celular em ratos com artrite induzida por CFA. Ratos Wistar fêmeas (200 - 250 g, n = 50 foram induzidos à monoartrite por adjuvante completo de Freund (CFA, Mycobacterium butyricum; 0,5 mg/mL; 50 μL na articulação do joelho direito (TF; n = 24 ou tornozelo direito (TT; n = 26. A incapacitação articular foi mensurada pelo tempo de elevação da pata (TEP; s em 1 minuto de avaliação. O edema do joelho ou tornozelo foi avaliado pela medida do diâmetro articular (AD, cm e pelo edema de pata (EP, mL, respectivamente. Ambos foram avaliados durante 10 dias consecutivos. Dois protocolos de exercício foram realizados: (a exercício constante (TF, n = 6; TT, n = 6, realizando 1 minuto diário de exercício no cilindro (3 r.p.m.; (b exercício variável (TF, n = 6; TT, n = 7, exercício com aumento de 1 minuto por dia, totalizando 10 minutos no último dia. Os grupos-controle (TF, n = 12; TT, n = 13 não realizaram exercício. Após 10 dias, os animais foram eutanasiados para contagem total (células/mm3 e diferencial (mononucleares e polimorfos nucleares; células/mm3 de leucócitos do tecido inflamado. O exercício variável inibiu a incapacitação e o edema em ambas as articulações. Entretanto, reduziu a migração total de leucócitos apenas na articulação TF. O exercício constante inibiu o edema nas duas articulações e reduziu a migração total de leucócitos da articulação TT. Porém, não reduziu a incapacitação. O exercício variável pareceu ser mais efetivo em reduzir os parâmetros inflamatórios em comparação com o exercício constante.

  17. Japan, quality tourist destiny: a learner option for Colima

    Directory of Open Access Journals (Sweden)

    Irma Magaña Carrillo

    2007-11-01

    Full Text Available In this research feature presentation some results are presented as "A Propose Plan to implement a Culture with Quality Control in Tourism Business making Mexico an Attractive site in the Asia-Pacific market and Active within the PATA organism in the XXI Millennium". Which was performed in Japan from 2001 to 2004. This thesis acquires the category of qualitative and emergent and it arouse as a first attempt in reaching the point of a systematic application of the theory of the Model for Total Quality through the Total Control of Quality to the tourist product its basis and service as well as to be delivered with the purpose of giving benefits to the Mexican tourist sector, so that it would provide a gaining position of tourist from Asia, mostly Japanese and in this way it would take advantage Mexico’s participation in PATA.During the search field wok several investigation works were carried out, such as depth interviews to top level management (owner and or proprietor manager level of service area from a ransom selection of some Japanese enterprises. It had the start point in the premise that most of the chosen Japanese business selected for search, are managed with own forms of management to serve the base service and deliver it with quality to reach the external customer satisfaction. In this presentation the analysis result of some interviews are shown. For the planned interviews, this search process used some techniques to get precise information whit sound impact on the research about the following key factors: a customer satisfaction in all their needs, b customer satisfaction in their expectations, c customer loyalty to their supplier.Data collected are qualitative and its informant source was bases on the facts of the way they live the reality of serving the base service or product, which whit its delivery and know-how to their external customer. Techniques application has been carefully revised inside the Japanese cultural context

  18. EVOLUTION OF ALLOMETRIC CHANGES IN FRUIT FLY LEGS: A DEVELOPMENTALLY ENTRENCHED STORY

    Directory of Open Access Journals (Sweden)

    Juan Nicolas MALAGON

    2016-01-01

    Full Text Available La alometría estudia los cambios de tamaño entre las diferentes partes del cuerpo de los seres vivos y sus implicaciones ecológicas y evolutivas. Aunque la mayoría de los estudios en esta área se han centrado en investigar la importancia de los cambios alométricos en la evolución fenótipica, pocos estudios han analizado como la interconexión de los diferentes procesos del desarrollo afectan dichos cambios de tamaño. Para investigar la relación entre los mecanismos de desarrollo y los cambios alométricos, utilizamos los peines sexuales de diferentes especies del género Drosophila. Dichas estructuras, constituidas por un grupo de sedas ubicadas en las patas anteriores de los machos, presentan una variedad morfológica sobresaliente durante la evolución. Por medio de análisis morfométricos entre diferentes especies de Drosophila, incluidas líneas de Drosophila melanogaster modificadas genéticamente, investigamos los cambios alométricos que ocurren en el tamaño de las patas y diferentes tipos de sedas como resultado de la radiación de los peines sexuales. En este trabajo presentamos evidencia que sugiere una interacción compleja entre los mecanismos del desarrollo encargados de definir la distancia entre las sedas y su movimiento. Además, mostramos que dichos mecanismos son fundamentales para entender cómo evoluciona la alometría en los segmentos tarsales. Aunque la emergencia de una nueva característica puede modificar las relaciones alométricas, los procesos ancestrales de desarrollo varían en su susceptibilidad de ser modificados. De igual forma, este trabajo muestra que la interconexión entre los diferentes procesos de desarrollo puede sesgar la dirección de los cambios morfológicos.

  19. HIV treatment and care services for adolescents: a situational analysis of 218 facilities in 23 sub-Saharan African countries.

    Science.gov (United States)

    Mark, Daniella; Armstrong, Alice; Andrade, Catarina; Penazzato, Martina; Hatane, Luann; Taing, Lina; Runciman, Toby; Ferguson, Jane

    2017-05-16

    In 2013, an estimated 2.1 million adolescents (age 10-19 years) were living with HIV globally. The extent to which health facilities provide appropriate treatment and care was unknown. To support understanding of service availability in 2014, Paediatric-Adolescent Treatment Africa (PATA), a non-governmental organisation (NGO) supporting a network of health facilities across sub-Saharan Africa, undertook a facility-level situational analysis of adolescent HIV treatment and care services in 23 countries. Two hundred and eighteen facilities, responsible for an estimated 80,072 HIV-infected adolescents in care, were surveyed. Sixty per cent of the sample were from PATA's network, with the remaining gathered via local NGO partners and snowball sampling. Data were analysed using descriptive statistics and coding to describe central tendencies and identify themes. Respondents represented three subregions: West and Central Africa (n = 59; 27%), East Africa (n = 77, 35%) and southern Africa (n = 82, 38%). Half (50%) of the facilities were in urban areas, 17% peri-urban and 33% rural settings. Insufficient data disaggregation and outcomes monitoring were critical issues. A quarter of facilities did not have a working definition of adolescence. Facilities reported non-adherence as their key challenge in adolescent service provision, but had insufficient protocols for determining and managing poor adherence and loss to follow-up. Adherence counselling focused on implications of non-adherence rather than its drivers. Facilities recommended peer support as an effective adherence and retention intervention, yet not all offered these services. Almost two-thirds reported attending to adolescents with adults and/or children, and half had no transitioning protocols. Of those with transitioning protocols, 21% moved pregnant adolescents into adult services earlier than their peers. There was limited sexual and reproductive health integration, with 63% of facilities offering

  20. Prevalence of Cryptosporidium-like infection in one-humped camels (Camelus dromedarius of northwestern Iran

    Directory of Open Access Journals (Sweden)

    Yakhchali M.

    2012-02-01

    Full Text Available Cryptosporidium is a ubiquitous enteropathogen protozoan infection affecting livestock worldwide. The present study was carried out to determine the prevalence of Cryptosporidium infection in different age groups of dromedary camels in northwestern Iran from November 2009 to July 2010. A total number of 170 fecal samples were collected and examined using modified Ziehl-Neelsen (MZN staining under light microscope. Examination of stained fecal smears revealed that 17 camels (10% were positive for Cryptosporidium-like. The prevalence of Cryptosporidium-like was significantly higher in camel calves (< 1 years old (20% than other age groups, in which the diarrhoeic calves had the prevalence of 16%. In adult camels the prevalence was 6.5%. There was no significant difference in the prevalence of Cryptosporidium-like between male and female camels. It is concluded that Cryptosporidium infection is a problem in camel husbandry and could be of public health concern in the region.

  1. Direct detection of Ehrlichia canis by PCR in the conjunctiva of a dog with bilateral anterior uveitis.

    Science.gov (United States)

    Walser-Reinhard, L; Schaarschmidt-Kiener, D; Forster, J L; Matheis, F; Spiess, B

    2012-04-01

    The following report describes the direct detection of Ehrlichia canis by real-time PCR in the conjunctiva of a 1-year-old female Maltese dog. After being imported from Brazil, the dog was presented because of anorexia, dehydration, fever, and palpable mandibular lymph nodes. A few days later, the dog developed bilateral blepharospasm, photophobia and anterior uveitis. Monocytic ehrlichia was diagnosed by a positive PCR result and the detection of IgM and IgG antibodies. Because of the massive uveitis a conjunctival sample was taken with a cytobrush, which also tested positive for Ehrlichia canis DNA by real-time PCR. Only one week after starting treatment with systemic doxycycline and local anti-inflammatory and cyclopalgic therapy the dog recovered from systemic and eye diseases. After therapy the follow-up examination revealed a full remission of clinical and hematological parameters and negative PCR result.

  2. FNIRS-based evaluation of cortical plasticity in children with cerebral palsy undergoing constraint-induced movement therapy

    Science.gov (United States)

    Cao, Jianwei; Khan, Bilal; Hervey, Nathan; Tian, Fenghua; Delgado, Mauricio R.; Clegg, Nancy J.; Smith, Linsley; Roberts, Heather; Tulchin-Francis, Kirsten; Shierk, Angela; Shagman, Laura; MacFarlane, Duncan; Liu, Hanli; Alexandrakis, George

    2015-03-01

    Sensorimotor cortex plasticity induced by constraint-induced movement therapy (CIMT) in six children (10.2 ± 2.1 years old) with hemiplegic cerebral palsy (CP) was assessed by functional near-infrared spectroscopy (fNIRS). The activation laterality index and time-to-peak/duration during a finger tapping task were quantified before, immediately after, and six months after CIMT. Five age-matched healthy children (9.8 ± 1.3 years old) were also imaged at the same time points to provide comparative activation metrics for normal controls. In children with CP the activation time-to-peak/duration for all sensorimotor centers displayed significant normalization immediately after CIMT that persisted six months later. In contrast to this longer term improvement in localized activation response, the laterality index that depended on communication between sensorimotor centers improved immediately after CIMT, but relapsed six months later.

  3. Socio-demographic disparities in the utilisation of general practice services for Australian children - Results from a nationally representative longitudinal study.

    Science.gov (United States)

    Ou, Lixin; Chen, Jack; Hillman, Ken

    2017-01-01

    This study aimed to investigate the pattern of general practice services utilization for Australian children and to examine socio-demographic disparities in general practitioner (GP) visits. We used the linked data from the nationally representative Longitudinal Study of Australian Children (LSAC) and the Medicare Australia claims data record. We used survey negative binomial and logistic regression to examine the socio-demographic factors associated with the utilisation of general practice services. The average number of annual GP visits gradually declined from 7.0 at 0-1 year old to 2.4 at 5-8 years (pSocio-demographic disparities existed in the utilisation of general practice services and varied at different age periods. Family socio-economic position, private health insurance coverage and region of residence strongly associates with the utilisation disparities over all age period. Further policy interventions are called to minimise the disparities in GP utilisation for children in Australian context.

  4. [A case of a child who developed Cushing reflex after a clinical diagnosis of brain death].

    Science.gov (United States)

    Enoki, Hideo

    2007-01-01

    The author presents a case of brain death caused by salmonella encephalopathy in a 1-year-old girl. The patient suffered from fever, convulsive status, and coma. On the 5th day, her respiration was arrested. At that time, we confirmed the absence of brainstem reflexes. An electroencephalogram (EEG) showed a flat pattern. Only wave I was recordable in auditory brainstem responses (ABR). On the 6th day, we obtained a flat EEG and a disappearance of all components of ABR. A simultaneous elevation of her heart rate and blood pressure was observed 14 to 18 hours after the respiratory arrest. This phenomenon was equivalent to the Cushing reflex, which represents an autoregulation against increased intracranial pressure. Our case suggested that the activity of a part of the brainstem was preserved in spite of the absence of activities in EEG, ABR and brainstem reflexes at 14 hours after the onset of apnea.

  5. TWO-STAGE SURGICAL TREATMENT OF A CHILD OF ONE YEAR FROM CONGENITAL HEART DISEASE AND BILIARY CIRRHOSIS

    Directory of Open Access Journals (Sweden)

    S. V. Gautier

    2014-01-01

    Full Text Available Aim: Clinical case of successful two-stage surgical treatment of a 1-year-old child with congenital heart disease and biliary cirrhosis is represented in this article. At the first day of life laparotomy was performed because of high intestinal obstruction. Kasai procedure and Roux-en-Y choledochojejunostomy were per- formed on 12th day and at the end of second month of life, respectively. Liver biopsy showed the signs of biliary cirrhosis. At the same time ventricular septal defect and atrial septal defect with pulmonary hyper- tension were diagnosed. The first step of treatment was the surgical septal defects closure. No complications during procedure, cardiopulmonary bypass and post-operative period were registered. There were no nega- tive effects on liver function after cardiac surgery. 11 months later living-donor liver transplantation was performed without any complications. Patient was discharged at 35th post-transplant day with stable graft function. 

  6. Leaching of mercury-containing cement monoliths aged for one year.

    Science.gov (United States)

    Svensson, Margareta; Allard, Bert

    2008-01-01

    A directive from the Swedish Government states that waste containing more than 1% of mercury shall be permanently deposited. The stabilization of mercury by conversion to a sparingly soluble compound like the sulphide is crucial to ensure long-term immobilization in a permanent storage. Immobilization by the solidification/stabilization (S/S) method and possible formation of HgS from mercury oxide or elemental mercury by reaction with a sulphur source (S or FeS) is investigated by a modified version of the NEN 7345 Dutch tank-leaching test. The diffusion of mercury during 11 months from 1-year-old mercury containing monoliths of Portland and slag cement is demonstrated. In a geologic repository under conditions representative of deep granitic bedrock (bicarbonate buffered to pH 8.6), a favourable monolith combination is slag cement with addition of the iron sulphide troilite. The apparent diffusion coefficient of mercury is estimated.

  7. Delleman Oorthuys syndrome

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    Syed Wajahat A Rizvi

    2015-01-01

    Full Text Available Oculocerebrocutaneous or Delleman syndrome is a rare congenital syndrome characterized by microphthalmia/anophthalmia with or without orbital cysts, focal skin defects, intracranial cysts and skin appendages. We here report a case of 1-year-old male child with periocular skin tags, lid colobomas, and dermal hypoplasia. The patient had delayed developmental milestones and history of tonic-clonic seizures. Magnetic resonance imaging of the head revealed a large arachnoid cyst, aplastic cerebellar vermis and polymicrographic pattern of the cerebral cortex. A complex cyst of spleen was also noted on abdominal ultrasonography. Orbital cysts depending on the size can be excised or left alone. Neuroimaging evaluation of patients with congenital orbital cysts and skin appendages is emphasized for early and appropriate management.

  8. Agammaglobulinemia in a Patient with Smith-Lemli-Opitz Syndrome: Case Report

    Directory of Open Access Journals (Sweden)

    H. Halik Akar

    2016-02-01

    Full Text Available Smith-Lemli-Opitz syndrome (SLO is a rare autosomal recessive (AR inherited genetic disorder characterized by multiple congenital anomalies, microcephaly, muscular hypotonia, and severe developmental delay. The deficiency of 7-dehydrocholesterol reductase enzyme leads to this syndrome. Patients with SLO display recurrent respiratory infections due to secondary muscular hypotonia which leads to decreased motility and respiratory effort. In this study, we report a 1-year-old boy with SLO presented with recurrent urinary infections and chronic diarrhea with Klebsiella pneumonia positivity in the rectal swabs. The patient had also markedly decreased immunoglobulin G (IgG between 50-100 g/dl. In follow-up of patient, markedly clinical improvement was observed with intravenous immunoglobulin (IVIG replacement. With this study, we would like to draw attention; recurrent infections may indicate primary immunodeficiencies such as agammaglobulinemia in patients with SLO.

  9. Effect of CO2 enhancement on beech (Fagus sylvatica L. seedling root rot due to Phytophthora plurivora and Phytophthora cactorum

    Directory of Open Access Journals (Sweden)

    Tkaczyk Miłosz

    2014-09-01

    Full Text Available Global climate change is associated with higher concentrations of atmospheric carbon dioxide (CO2. The ongoing changes are likely to have significant, direct or indirect effects on plant diseases caused by many biotic agents such as phytopathogenic fungi. This study results showed that increased CO2 concentration did not stimulate the growth of 1-year-old beech Fagus sylvatica L seedlings but it activated pathogenic Phytophthora species (P. plurivora and P. cactorum which caused significant reduction in the total number of fine roots as well as their length and area. The results of the greenhouse experiment indicated that pathogens once introduced into soil survived in pot soil, became periodically active (in sufficient water conditions and were able to damage beech fine roots. However, the trees mortality was not observed during the first year of experiment. DNA analyses performed on soil and beech tissue proved persistence of introduced Phytophthora isolates.

  10. Effect of spatial differences in growth on distribution of seasonally co-occurring herring Clupea harengus stocks

    DEFF Research Database (Denmark)

    Worsøe Clausen, Lotte; Stæhr, Karl-Johan; Rindorf, Anna

    2015-01-01

    over time. Contrary to previous perception of the juvenile migration, NSAS were found to leave the study area at the age between 1 and 2 years and WBSS 1 year olds were encountered in the Skagerrak. The estimated parameters of von Bertalanffy growth equations showed marked differences between areas...... with fish in the eastern part of the area having the lowest size at age at all ages. Further, their growth conditions appeared to deteriorate progressively over the period studied. Both NSAS and WBSS showed the highest condition in the North Sea and Skagerrak while condition was substantially lower in age...... Kattegat. The westward movement of spring spawners over time suggests that growth rate and possibly density of conspecifics influence the migration pattern and distribution of C. harengus in the area. In contrast, there was no evidence to suggest that distribution was constant over time within stocks...

  11. Changes in the Essential Oil Composition in the Needles of Scots Pine (Pinus sylvestris L. Under Anthropogenic Stress

    Directory of Open Access Journals (Sweden)

    Asta Judzentiene

    2007-01-01

    Full Text Available Unfavorable anthropogenic factors, such as air pollution, lead to biochemical responses in trees. Changes in the amounts of secondary metabolites may be early indicators of invisible injuries. The aim of this study was to evaluate composition of the essential oils in the needles of Scots pine (Pinus sylvestris L. growing in the areas affected by pollutant emissions of main factories in Lithuania: a nitrogen fertilizer factory (NFF, a cement factory (CF, and an oil refinery (OR. Totally, 14 pine stands were examined along transects from the factories (July 2005. Volatile components of the needles were extracted and analyzed by GC and GC/MS. Over 70 components of the essential oils were identified in current-year and 1-year-old needles.

  12. EXPERIENCE OF MEDICINAL FEEDING OF CHILDREN WITH NONINFECTIOUS DIARRHEA IN SOMATIC IN HOSPITAL DEPARTMENT

    Directory of Open Access Journals (Sweden)

    A.S. Eiberman

    2007-01-01

    Full Text Available The authors highlight the experience of the balanced low fat and low lactose mixture with medium chain triglycerides application among children with noninfectious diarrhea and hypotrophy (aged between 3 months and 1 year old, n = 21. All the children underwent artificial feeding, while the co program showed signs of amylorrhea and steatorrhea among most children. Owing to the mixture feeding, most children showed an in crease of body mass, normalization of co program and peripheral blood indices. The high mixture efficacy was confirmed among 11 children in their first months of life with different surgical pathology accompanied by the stool disorders in the postoperative period. The use of the given mixture allowed for the stool normalization, stoppage of enteral losses and rate stabilization of the body mass increase at early stages already in conditions of the resuscitation department.Key words: children, artificial feeding, diarrhea, medium chain triglycerides.

  13. Do we see eye to eye? Chinese mothers' and fathers' parenting beliefs and values for toddlers in Canada and China.

    Science.gov (United States)

    Chuang, Susan S; Su, Yanjie

    2009-06-01

    This study explores maternal and paternal parenting practices (authoritative or authoritarian) and parental values and goals for toddlers among Chinese mothers and fathers in Canada and China. The participants included 126 families of 1-year-old toddlers (67 Chinese Canadians and 59 mainland Chinese). The findings revealed that Chinese Canadian parents were more supportive of authoritative practices, and Chinese parents were more likely to support authoritarian practices. Between mothers and fathers, gender differences were found within countries. Interparental agreement for parenting beliefs varied by infant gender and country. For parental values, parents generally endorsed self-confidence as the most important trait for their toddlers. Endorsement of other traits (collectivistic and individualistic) varied in importance. Links among parenting beliefs and desired personality traits for their children were also explored. Copyright 2009 APA, all rights reserved.

  14. Infratentorial medulloepithelioma with divergent differentiation: Possibly a predictor of poor outcome

    Directory of Open Access Journals (Sweden)

    Indranil Chakrabarti

    2012-01-01

    Full Text Available Medulloepitheliomas (WHO grade IV are rare, malignant embryonal tumors of pediatric population, classified under the central nervous system (CNS primitive neuroectodermal tumors (PNET. Histologically, these tumors are characterized by neoplastic neuroepithelium recapitulating the embryonic neural tube. We describe a rare case of infratentorial medulloepithelioma with divergent differentiation in a 1-year-old male child who presented with headache, vomiting, and seizures. Histopathologic examination of the excised tumor revealed the characteristic neuroepithelium, along with other areas showing primitive neuroectodermal (blastemal cells in sheets, ependymoblastic rosettes, and nodular areas of neuronal differentiation. Possibly, this proliferating immature neuroepithelium is the cause of poor outcome in medulloepitheliomas. Due to the rarity of these tumors, it remains to be established whether infratentorial location or tumors with divergent differentiation are also predictors of adverse prognosis.

  15. Infratentorial medulloepithelioma with divergent differentiation: Possibly a predictor of poor outcome.

    Science.gov (United States)

    Chakrabarti, Indranil; Majumdar, Kaushik; Giri, Amita

    2012-05-01

    Medulloepitheliomas (WHO grade IV) are rare, malignant embryonal tumors of pediatric population, classified under the central nervous system (CNS) primitive neuroectodermal tumors (PNET). Histologically, these tumors are characterized by neoplastic neuroepithelium recapitulating the embryonic neural tube. We describe a rare case of infratentorial medulloepithelioma with divergent differentiation in a 1-year-old male child who presented with headache, vomiting, and seizures. Histopathologic examination of the excised tumor revealed the characteristic neuroepithelium, along with other areas showing primitive neuroectodermal (blastemal) cells in sheets, ependymoblastic rosettes, and nodular areas of neuronal differentiation. Possibly, this proliferating immature neuroepithelium is the cause of poor outcome in medulloepitheliomas. Due to the rarity of these tumors, it remains to be established whether infratentorial location or tumors with divergent differentiation are also predictors of adverse prognosis.

  16. Optimization of pediatric chest radiographic images using optical densities ratio

    Energy Technology Data Exchange (ETDEWEB)

    Souza, Rafael T.F.; Miranda, Jose R.A. [Universidade Estadual Paulista Julio de Mesquita Filho (UNESP), Botucatu, SP (Brazil). Inst. de Biociencias de Botucatu; Pina, Diana R. [Faculdade de Medicina de Botucatu (UNESP), Botucatu, SP (Brazil). Hospital das Clinicas. Dept. de Doencas Tropicais e Diagnostico por Imagem; Duarte, Sergio B. [Centro Brasileiro de Pesquisas Fisicas (CBPF/MCT), Rio de Janeiro, RJ (Brazil)

    2011-07-01

    The aim of this study is the optimization of radiographic images for the pediatric patients in the age range between 0 and 1 years old, through Optical Density Ratio (ODR), considering that pediatric patients are overexposed to radiation in the repeated attempts to obtain radiographic images considered of good quality. The optimization of radiographic techniques was carried out with the RAP-PEPP (Realistic Analytical Phantom coupled to homogeneous Phantom Equivalent to Pediatric Patient) phantom in two incubators and one cradle. The data show that the clinical routine radiographic techniques generate low-quality images at up to 18.8% when evaluated by the ODRs, and increases in doses up to 60% when compared to the optimized techniques doses. (author)

  17. Effects of NaCl Stress on Chlorophyll Fluorescence Parameters in Cinnamomum japonicum var. chenii%NaCl胁迫对普陀樟叶绿素荧光参数的影响

    Institute of Scientific and Technical Information of China (English)

    李影丽; 汪奎宏; 杜国坚; 许利群; 杨华; 肖纪军

    2008-01-01

    [Objective] Study on the changes of chlorophyll fluorescence parameters in Cinnamomum japonicum var. chenii under NaCl stress. [Method] The seedling growth increment, chlorophyll content and chlorophyll fluorescence parameters in leaves of 1-year old Cinnamomum japonicum var. chenii were investigated in field experiment. [Result] Under NaCl stress, seedling growth increment reduced and the chlorophyll content decreased to a stable value; changes of Fv/Fm and Fv/Fo showed identical increasing trend and double peak type. With the aggravation of salt stress, most variations were ob- served in Fo, correlations among chlorophyll fluorescence parameters presented "rise-drop" trend (in the treatment of 7 g/L NaCl). [Condusion] Cinna-momum japonicum var. chenii is endowed with strong salt resistance and wide adaptability.

  18. Advanced multimodality imaging of an anomalous vessel between the ascending aorta and main pulmonary artery in a dog.

    Science.gov (United States)

    Markovic, Lauren E; Kellihan, Heidi B; Roldán-Alzate, Alejandro; Drees, Randi; Bjorling, Dale E; Francois, Chris J

    2014-03-01

    A 1-year-old male German shorthaired pointer was referred for evaluation of tachypnea and hemoptysis. A grade VI/VI left basilar continuous murmur was ausculted. Multimodality imaging consisting of thoracic radiographs, transthoracic and transesophageal echocardiography, fluoroscopy-guided selective angiography, computed tomography angiogram (CTA) and magnetic resonance angiogram (MRA), was performed on this patient. The defect included a left-to-right shunting anomalous vessel between the ascending aorta and main pulmonary artery, along with a dissecting aneurysm of the main and right pulmonary artery. An MRA post-processing technique (PC VIPR) was used to allow for high resolution angiographic images and further assessment of the patient's hemodynamics prior to surgical correction. This case report describes the clinical course of a canine patient with a rare form of congenital cardiac disease, and the multiple imaging modalities that were used to aid in diagnosis and treatment.

  19. Height, weight and body mass index in early adulthood and risk of schizophrenia

    DEFF Research Database (Denmark)

    Sørensen, Holger Jelling; Mortensen, E L; Reinisch, J M;

    2006-01-01

    individuals born between 1959 and 1961. In 1999, cases of schizophrenia were identified in the Danish Psychiatric Central Register, and the cases were compared with the cohort pool of controls with respect to height, weight, and BMI from draft records. The effect of low BMI was adjusted for parental social......OBJECTIVE: To illuminate the possible associations between height, weight, and body mass index (BMI) during early adulthood and the development of schizophrenia. METHOD: This prospective study is based on an all-male sample of 3210 individuals from the Copenhagen Perinatal Cohort, comprising...... status when the cohort members were 1 year old, birth weight, birth length, and maternal pre-pregnancy BMI. RESULTS: Forty-five cases of schizophrenia had a lower young adult mean body weight and BMI than controls. A significant inverse relationship between BMI and risk of later schizophrenia was found...

  20. Sudden death in a captive meerkat (Suricata suricatta with arterial medial and myocardial calcification

    Directory of Open Access Journals (Sweden)

    Laura Bongiovann

    2016-04-01

    Full Text Available A 1-year-old male meerkat was found dead by the owner. The animal was clinically healthy and was regularly vaccinated for distemper virus. Necropsy revealed multifocal to confluent dry white areas in the myocardium, pneumonia and congestive hepatopathy. All the other organs, including gross vessels, were macroscopically normal. The heart showed histologically large, multifocal to confluent areas of mineralization of the myocardium and the wall of small coronary artery. Vascular calcifications were also observed in the hepatic portal tracts and kidneys arteries of small/medium sizes. The arterial lumen appeared narrowed and the wall thickened due to the calcification of the tunica media. In veterinary medicine, arterial mineralization is regarded as a metastatic calcification, as the result of hypercalcemia and/or hyperphosphatemia. However, today, the pathogenesis of medial artery calcification in humans seems to be the results of an active process resembling embryonic osteogenesis, rather than a mere passive process.

  1. Airway management in Escobar syndrome: A formidable challenge

    Directory of Open Access Journals (Sweden)

    Shaji Mathew

    2013-01-01

    Full Text Available Escobar syndrome is a rare autosomal recessive disorder characterized by flexion joint and digit contractures, skin webbing, cleft palate, deformity of spine and cervical spine fusion. Associated difficult airway is mainly due to micrognathia, retrognathia, webbing of neck and limitation of the mouth opening and neck extension. We report a case of a 1 year old child with Escobar syndrome posted for bilateral hamstrings to quadriceps transfer. The child had adequate mouth opening with no evidence of cervical spine fusion, yet we faced difficulty in intubation which was ultimately overcome by securing a proseal laryngeal mask airway (PLMA and then by intubating with an endotracheal tube railroaded over a paediatric fibreoptic bronchoscope passed through the lumen of a PLMA.

  2. Measurement of ethylene emission from Japanese red pine (Pinus densiflora) under field conditions in NOx-polluted areas.

    Science.gov (United States)

    Kume, A; Tsuboi, N; Nakatani, N; Nakane, K; Sakurai, N; Nakagawa, N; Sakugawa, H

    2001-01-01

    Emission of ethylene from the needles of Japanese red pine, Pinus densiflora, was measured in air-polluted areas in Hiroshima, Japan. We applied a suitable protocol to determine the rate of ethylene emission from the excised needles. The influence of excision of needles on ethylene emission was not detected during the first 4 h of incubation at 20 degrees C. Ethylene emissions were low in the unpolluted (clean) areas regardless of the altitude or season. The emission of stress ethylene increased with the atmospheric NO2 concentration, suggesting that atmospheric NOx or related substances induced the higher ethylene emission in the polluted areas (near urban and industrial areas). In all cases, 1-year-old needles emitted significantly larger amounts of ethylene than the current needles. Ethylene emission did not increase evenly in the polluted areas, but the frequency of trees emitting high ethylene increased. Therefore, threshold rates for the baseline ethylene emission were proposed.

  3. Measurement of ethylene emission from Japanese red pine (Pinus densiflora) under field conditions in NO{sub x}-polluted areas

    Energy Technology Data Exchange (ETDEWEB)

    Kume, A.; Nakatani, N. [Hiroshima Univ., Center for Forest Decline Studies, Higashi-Hiroshima (Japan); Tsuboi, N.; Nakane, K. [Hiroshima Univ., Dept. of Environmental Dynamics and Management, Hiroshima (Japan); Sakurai, N.; Nakagawa, N.; Sakugawa, H. [Hiroshima Univ., Dept. of Environmental Studies, Hiroshima (Japan)

    2001-07-01

    Emission of ethylene from the needles of Japanese red pine, Pinus densiflora, was measured in air-polluted areas in Hiroshima, Japan. We applied a suitable protocol to determine the rate of ethylene emission from the excised needles. The influence of excision of needles on ethylene emission was not detected during the first 4 h of incubation at 20degC. Ethylene emissions were low in the unpolluted (Clean) areas regardless of the altitude or season. The emission of stress ethylene increased with the atmospheric NO{sub 2} concentration, suggesting that atmospheric NO{sub x} or related substances induced the higher ethylene emission in the polluted areas (near urban and industrial areas). In all cases, 1-year-old needles emitted significantly larger amounts of ethylene than the current needles. Ethylene emission did not increase evenly in the polluted areas, but the frequency of trees emitting high ethylene increased. Therefore, threshold rates for the baseline ethylene emission were proposed. (Author)

  4. Prevenção de anemia no primeiro ano de vida em centros de saúde do município de Santo André, São Paulo

    DEFF Research Database (Denmark)

    Szarfarc, S C; Berg, Gabriele; Santos, A L

    1996-01-01

    The aim of this study was to evaluate the efficacy of an iron prophylactic supplementation program, in three health centers of Santo André, in São Paulo state. The prevalence of anemia was identified in a control group consisting of 201 children of 1 year old. The intervention group consisted...... and anemia and its risk to children's health. When the children were 12 months old, the diagnosis of anemia was made through dosage of hemoglobin concentration and the results were compared with those of the control group. It was verified that the 2 groups presented similar prevalences. It is important...... to realize that children with low frequency of visits to the health centers had prevalence of anemia significantly higher than those with high frequency. Some factors that possibly contributed to the result of the intervention are discussed....

  5. First report of oligodendroglioma in a sheep : clinical communication

    Directory of Open Access Journals (Sweden)

    A. Derakhshanfar

    2010-05-01

    Full Text Available Oligodendrogliomas occur most commonly in the dog, but have also been reported in cattle, horses and cats. A 1-year-old sheep with neurological disturbances, including blindness, ataxia, circling and incoordination was referred to the veterinary clinic of Shahid Bahonar University of Kerman. Following euthanasia and necropsy, a soft, relatively well-demarcated mass was observed in the white and grey matter of the right cerebral hemisphere, close to the sylvian fissure in the right cerebral hemisphere. Microscopic examination revealed a sheet of densely packed tumour cells with hyperchromatic nuclei, lightly staining cytoplasm and characteristic perinuclear halo effect which is consistent with a diagnosis of oligodendroglioma. This is the 1st report of oligodendroglioma in sheep.

  6. Analysis of pediatric burns in Nagasaki University from 1983 to 2002.

    Science.gov (United States)

    Akita, Sadanori; Nakagawa, Hiroshi; Tanaka, Katsumi; Hirano, Akiyoshi

    2005-12-01

    Pediatric burns are frequently observed: twenty-year burn analysis was performed in a single department, and 354 cases, aged 0-6 years old. The major cause of pediatric burns was scalding (68%) and hot water comprised over half of the scald burns. At 1 year old and younger, the total burn surface area (TBSA) was significantly smaller than from 1 to 6 years old (4.8+/-9.56 versus 10.5+/-18.86%, respectively, pburns was significantly greater than contact burns (8.9+/-15.76 versus 0.9+/-2.0%, respectively, ppatients (18%) and 126 patients were hospitalized (34%). Compared to the first decade of analysis, the second decade had fewer patients (222 versus 142 cases) and lower severity (7.4+/-14.6% versus 6.6+/-13.26%, TBSA). Pediatric burns in younger children should be studied closely as to their causes and with further follow-up.

  7. Contiguous triple spinal dysraphism associated with Chiari malformation Type II and hydrocephalus: an embryological conundrum between the unified theory of Pang and the unified theory of McLone.

    Science.gov (United States)

    Dhandapani, Sivashanmugam; Srinivasan, Anirudh

    2016-01-01

    Triple spinal dysraphism is extremely rare. There are published reports of multiple discrete neural tube defects with intervening normal segments that are explained by the multisite closure theory of primary neurulation, having an association with Chiari malformation Type II consistent with the unified theory of McLone. The authors report on a 1-year-old child with contiguous myelomeningocele and lipomyelomeningocele centered on Type I split cord malformation with Chiari malformation Type II and hydrocephalus. This composite anomaly is probably due to select abnormalities of the neurenteric canal during gastrulation, with a contiguous cascading impact on both dysjunction of the neural tube and closure of the neuropore, resulting in a small posterior fossa, probably bringing the unified theory of McLone closer to the unified theory of Pang.

  8. Prevalence of mutans streptococci in one-year-old children.

    Science.gov (United States)

    Grindefjord, M; Dahllof, G; Wikner, S; Hojer, B; Modeer, T

    1991-10-01

    Colonization with mutans streptococci was studied in 1095 1-year-old children living in suburban Stockholm. During a scheduled vaccination appointment at a child health centre, a bacterial sample was obtained from the child's tongue and a structured questionnaire was completed by the accompanying parent. Six percent of the subjects were colonized with mutans streptococci. The variables most strongly correlated with presence of mutans streptococci were: non-Swedish background, consumption of sugar-containing beverages at night and total consumption of sugar-containing beverages. The results indicate that, by the age of 1 year, maternally influenced behaviour patterns such as dietary habits that may predispose to early colonization of mutans streptococci are already established. Such early colonization with mutans streptococci may predict high caries risk in the primary dentition.

  9. Unilateral anterior persistent fetal vasculature in a child with blepharophimosis-ptosis-epicanthus inversus syndrome: A surgical challenge

    Directory of Open Access Journals (Sweden)

    Vasudha Kemmanu

    2016-01-01

    Full Text Available Blepharophimosis-ptosis-epicanthus inversus syndrome (BPES is a rare autosomal dominant genetic disease. It is clinically characterized by four major features; blepharophimosis, ptosis, epicanthus inversus, and telecanthus. We report a case of a 1-year-old female with BPES with unilateral anterior persistent fetal vasculature (PFV. On examination, she was found to have all the clinical features of BPES, along with calcified and partially absorbed cataract with elongated ciliary processes in her left eye. B-scan of left eye showed attached retina with no evidence of posterior PFV. Systemic examination was normal. She underwent cataract surgery with primary posterior capsulotomy with intraocular lens implantation under general anesthesia. Literature search did not reveal any previous reports of unilateral anterior PFV and BPES. The clinical features, other associations, and the difficulties in the surgical management of this condition are discussed.

  10. Intervention analysis of introduction of rotavirus vaccine on hospital admissions rates due to acute diarrhea

    Directory of Open Access Journals (Sweden)

    Maria de Lourdes Teixeira Masukawa

    2014-10-01

    Full Text Available The aim of this study is to investigate the impact of rotavirus vaccine on hospitalization rates for acute diarrhea in children younger than 5 years old after the introduction of the vaccine in 2006. A descriptive analytical observational study was carried out of the hospitalization rates occurred between 2000 and 2011 in 22 Regional Health Centers of Paraná State, Brazil. The effect of the vaccine was assessed by applying the SARIMA/Box-Jenkins time series methodology of intervention analysis, which allows verifying the slopes of the series are different after the introduction of the vaccine and estimating the magnitude of these effects for children younger than five years of age, by age group, for each region center. It was verified a statistically significant reduction by center/month on hospitalization rates for children 1 year old and younger, with averages of 47% and 58%, respectively, in December 2011.

  11. Nationwide survey of bovine leukemia virus infection among dairy and beef breeding cattle in Japan from 2009-2011.

    Science.gov (United States)

    Murakami, Kenji; Kobayashi, Sota; Konishi, Misako; Kameyama, Ken-ichiro; Tsutsui, Toshiyuki

    2013-01-01

    A nationwide survey of bovine leukemia virus (BLV) infection was conducted among dairy and beef breeding cattle in Japan from 2009-2011 using an enzyme-linked immunosorbent assay. Of a total of 20,835 cattle tested, 35.2% were seropositive for BLV and the animal type-level seroprevalences in dairy and beef breeding cattle were 40.9 and 28.7%, respectively. By the time animals were 1 year old, 21.0% of dairy and 13.7% of beef breeding cattle were considered infected. Our findings indicate that BLV is widespread among dairy and beef breeding cattle in Japan with the BLV seroprevalences approximately 10- and 4-fold higher, respectively, than previously reported for 1980-1982 in Japan.

  12. Microbial diversities (16S and 18S rRNA gene pyrosequencing) and environmental pathogens within drinking water biofilms grown on the common premise plumbing materials unplasticized polyvinylchloride and copper.

    Science.gov (United States)

    Buse, Helen Y; Lu, Jingrang; Lu, Xinxin; Mou, Xiaozhen; Ashbolt, Nicholas J

    2014-05-01

    Drinking water (DW) biofilm communities influence the survival of opportunistic pathogens, yet knowledge about the microbial composition of DW biofilms developed on common in-premise plumbing material is limited. Utilizing 16S and 18S rRNA gene pyrosequencing, this study characterized the microbial community structure within DW biofilms established on unplasticized polyvinyl chloride (uPVC) and copper (Cu) surfaces and the impact of introducing Legionella pneumophila (Lp) and Acanthamoeba polyphaga. Mature (> 1 year old) biofilms were developed before inoculation with sterilized DW (control, Con), Lp, or Lp and A. polyphaga (LpAp). Comparison of uPVC and Cu biofilms indicated significant differences between bacterial (P = 0.001) and eukaryotic (P 0.05) but did affect eukaryotic members (uPVC, P < 0.01; Cu, P = 0.001). Thus, established DW biofilms host complex communities that may vary based on substratum matrix and maintain consistent bacterial communities despite introduction of Lp, an environmental pathogen.

  13. [Surgical Treatment of Large Muscular Ventricular Septal Defect nearby the Moderator Band Using the Sandwich Method;Report of a Case].

    Science.gov (United States)

    Motokawa, Mamika; Sasahara, Akihiro; Terakawa, Katsunari; Miyamoto, Takashi

    2016-09-01

    We describe the rare case of a 1-year-old girl who had large muscular ventricular defect (VSD) nearby the moderator band. We experienced the patch closure using sandwich method. A 1-month-old girl was referred to our institution for treatment of muscular VSD. At the age of 2 month, she underwent the pulmonary artery banding to control the pulmonary high flow. After follow up, the patient have reached 70 cm tall and weighed 7 kg. One year after the "sandwich operation", cardiac catheterization revealed the tiny residual shunt. Nevertheless, the cardiac function was good and the growth was in fine fettle. Sandwich method is a useful surgical technique to close the muscular VSD without resect the right ventricular trabeculation.

  14. An unusual case of intestinal leiomyositis in a Bernese mountain dog.

    Science.gov (United States)

    Gianella, P; Tecilla, M; Bellino, C; Buracco, R; Martano, M; Zanatta, R; Cagnasso, A; D'angelo, A

    2015-10-01

    A 1-year-old, female Bernese mountain dog was presented to the Veterinary Teaching Hospital of Turin University with a 3-month history of weight loss, intermittent anorexia, vomiting, constipation, and abdominal distension. Full-thickness biopsies from the stomach, duodenum, jejunum and ileum were collected for histological and immunohistochemical examination. Microscopic lesions displayed severe diffuse degeneration and loss of leiomyocytes, with lymphocytic leiomyositis, fibroplasia, angiogenesis, severe diffuse neuronal atrophy, and ganglioneuritis in the myenteric (Auerbach's) plexus. A diagnosis of chronic idiopatic intestinal pseudo-obstruction was made. Response to immunosuppressive therapy was poor and the dog was humanely euthanized. Unique findings were mononuclear infiltration composed predominantly of B-cell, angiogenesis and weak immunoreactivity for neuron-specific enolase.

  15. Glycolic acid physical properties and impurities assessment

    Energy Technology Data Exchange (ETDEWEB)

    Lambert, D. P. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Pickenheim, B. R. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Hay, M. S. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); BIBLER, N. E. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2017-08-09

    This document has been revised to add analytical data for fresh, 1 year old, and 4 year old glycolic acid as recommended in Revision 2 of this document. This was needed to understand the concentration of formaldehyde and methoxyacetic acid, impurities present in the glycolic acid used in Savannah River National Laboratory (SRNL) experiments. Based on this information, the concentration of these impurities did not change during storage. These impurities were in the glycolic acid used in the testing included in this report and in subsequent testing using DuPont (now called Chemours) supplied Technical Grade 70 wt% glycolic acid. However, these impurities were not reported in the first two versions of this report. The Defense Waste Processing Facility (DWPF) is planning to implement a nitric-glycolic acid flowsheets to increase attainment to meet closure commitment dates during Sludge Batch 9. In fiscal year 2009, SRNL was requested to determine the physical properties of formic and glycolic acid blends.

  16. Unilateral anterior persistent fetal vasculature in a child with blepharophimosis-ptosis-epicanthus inversus syndrome: A surgical challenge

    Science.gov (United States)

    Kemmanu, Vasudha; Rathod, Pragnya; Anaspure, Hemant; Yadav, Naresh K

    2016-01-01

    Blepharophimosis-ptosis-epicanthus inversus syndrome (BPES) is a rare autosomal dominant genetic disease. It is clinically characterized by four major features; blepharophimosis, ptosis, epicanthus inversus, and telecanthus. We report a case of a 1-year-old female with BPES with unilateral anterior persistent fetal vasculature (PFV). On examination, she was found to have all the clinical features of BPES, along with calcified and partially absorbed cataract with elongated ciliary processes in her left eye. B-scan of left eye showed attached retina with no evidence of posterior PFV. Systemic examination was normal. She underwent cataract surgery with primary posterior capsulotomy with intraocular lens implantation under general anesthesia. Literature search did not reveal any previous reports of unilateral anterior PFV and BPES. The clinical features, other associations, and the difficulties in the surgical management of this condition are discussed. PMID:27488160

  17. Burnei’s disease: teratological spondylolysis

    Science.gov (United States)

    Gavriliu, ST; Ghiță, RA; El Nayef, T; Burnei, A; Olaru-Barbilian, CR

    2015-01-01

    Teratological spondylolysis is a pathological entity noted for the first time in the specialty literature by Gh. Burnei in “The Spine Journal”, in September 25, 2014. This disease was described in a short presentation of the first case treated by the author. The aim of this paper was to expose in a didactic manner the main characteristic aspects of Burnei’s disease: embryological, clinical, imaging and treatment data and also to make known this pathological entity with all its pathognomonic diagnostic elements. This paper was based on data obtained after analyzing 2 cases of teratological spondylolysis: a 18-year-old patient with triple L3-L5 teratological spondylolysis with Pang 1 spinal dysraphism and a 1-year-old child with teratological spondylolysis and retrospondylolisthesis. PMID:26664464

  18. Breath test measurements in combination with indirect calorimetry for estimation of 13C-leucine oxidation in mink (Mustela vison)

    DEFF Research Database (Denmark)

    Tauson, Anne-Helene; Ali, Abdalla; Kanska, Katarzyna

    2000-01-01

    Gas exchange measurements by means of indirect calorimetry can be used to calculate quantitative substrate oxidation. The results represents average net oxidation values (substrate disappearance rate), but they cannot describe the dynamics of the oxidation processes. Breath test measurements...... to feeding and fasting. Twelve 1-year-old male mink (Mustela vison) were measured in each five consecutive periods by means of indirect calorimetry and simultaneous breath test. In Periods 1, 3 and 5, each lasting 3 days, the animals were fed ad libitum and Periods 2 and 4 were fasting periods, each of 48 h...... before measurements started and expired air was then sucked out of the respiration chamber and collected into breath bags at frequent intervals until 5.5 h after the start of measurements. The ratio of 13C/12C was measured by means of an IRIS infrared analyser and results are reported in terms of delta...

  19. Reconstruction of Internal and External Exposures of Fukushima Residents.

    Science.gov (United States)

    Akahane, Keiichi

    2016-09-01

    After the Fukushima Daiichi nuclear power plant accident, the internal and external exposures of the residents have been very important issues and concerns. Fukushima prefectural government and Fukushima medical university have been performing the Fukushima Health Management Survey, and the external exposures of the residents have been estimated in the survey by using NIRS external dose estimation system. The doses of 66.3% residents were >1 mSv, and 94.8 % were >2 mSv. For estimating internal exposures of the residents, thyroid measurements, whole body counter measurements and simulation have been applied. These three approach estimations showed that the 90 percentile of thyroid equivalent doses were 10-30 mSv for 1-year-old baby and were 10-20 mSv or less for adults.

  20. Effectiveness of early preventive intervention with semiannual fluoride varnish application in toddlers living in high-risk areas

    DEFF Research Database (Denmark)

    Anderson, Maria; Dahllöf, Göran; Twetman, Svante

    2016-01-01

    This study evaluated whether toddlers in an extended preventive program of semiannual fluoride varnish applications from 1 year of age had a lower incidence of caries than those undergoing a standard program. A cohort of 1-year-old children (n = 3,403) living in multicultural areas of low...... socioeconomic standing in Stockholm participated in a cluster-randomized controlled field trial with two parallel arms. The children attended 23 dental clinics. Using the ICDAS II criteria, the examiners recorded caries at baseline and after 1 and 2 years. The children in the reference group received...... a standardized oral health program once yearly between 1 and 3 years of age. The children in the test group received the same standard program supplemented with topical applications of fluoride varnish every 6 months. We compared the test group and the reference group for the prevalence and increment of caries...

  1. Genome sequence and description of Anaeromassilibacillus senegalensis gen. nov., sp. nov., isolated from the gut of patient with kwashiorkor

    Directory of Open Access Journals (Sweden)

    E. Guilhot

    2017-05-01

    Full Text Available Using the culturomics strategy, a wide range of anaerobic bacteria was discovered including Anaeromassilibacillus senegalensis strain mt9T (= CSUR P1511=DSM 102954, isolated from the gut microbiota of a 1-year-old Senegalese patient with kwashiorkor. This Gram-negative strain is a strictly anaerobic, spore-forming rod motile by a polar flagellum. The 3 511 289 bp long genome of this strain contains 3046 protein-coding and 49 RNA genes, including 45 tRNA and four rRNA genes, and exhibits a G+C content of 52.94%. Here we describe the features of this organism, together with the complete genome sequence and annotation.

  2. Dystocia Ystocia Due to Due to Mummifiedummified Foetaloetal Monsteronster in ain a Yankasaankasa Ewewe: A Casease Reporteport

    Directory of Open Access Journals (Sweden)

    A.I. Kisani

    2012-06-01

    Full Text Available A 1 year old Yyankasa ewe weighing 24 kg was presented to the Large Animal Clinic unit of the Veterinary Teaching Hospital, University of Agriculture Makurdi, Nigeria. The owner with the complained t that she has been in labour for 24 h without delivery. Vital parameters were taken and found to be within the normal ranges. the The patient underwent general and obstetrical animal was examinationed. A diagnosis of dystocia was made with Tthe foetus was found to be in anterior presentation of the fetus, bilateral with the carpalus and shoulder flexioned and the neck deviated laterally.lateral deviation of the neck. Manual traction to deliver the foetus was not successful. Caesarean section was performed with the patient under sedation and epidural anaesthesiatherefore recommended. This was carried out and the dead foetus removed. Recovery post surgery was complete and the ewe was discharged five days post surgery.

  3. Generation of poikiloderma with neutropenia (PN) induced pluripotent stem cells (iPSCs).

    Science.gov (United States)

    Mills, Jason A; Hudock, Kristin M; Sullivan, Spencer K; Herrera, Pamela; Sullivan, Lisa M; Gadue, Paul; French, Deborah L

    2015-11-01

    Poikiloderma with neutropenia (PN, Clericuzio-type poikiloderma with neutropenia) is a rare autosomal recessive disorder caused by biallelic mutations in the USB1 gene (Alias C16orf57 and MPN1). To date, there have been only 37 reported cases worldwide of this disorder that presents with neutropenia, early onset poikiloderma, respiratory infections, palmo-plantar hyperkeratosis, and skeletal defects. Here we described the generation of human induced pluripotent stem cell lines (PN1 and PN2) from the peripheral blood of a 1-year-old patient using the dox-inducible STEMCCA vector. This patient presented with bacteremia, pneumonia, and neutropenia. Analysis of bone marrow demonstrated normal cellularity with trilineage hematopoiesis and neutropenia.

  4. Generation of poikiloderma with neutropenia (PN induced pluripotent stem cells (iPSCs

    Directory of Open Access Journals (Sweden)

    Jason A. Mills

    2015-11-01

    Full Text Available Poikiloderma with neutropenia (PN, Clericuzio-type poikiloderma with neutropenia is a rare autosomal recessive disorder caused by biallelic mutations in the USB1 gene (Alias C16orf57 and MPN1. To date, there have been only 37 reported cases worldwide of this disorder that presents with neutropenia, early onset poikiloderma, respiratory infections, palmo-plantar hyperkeratosis, and skeletal defects. Here we described the generation of human induced pluripotent stem cell lines (PN1 and PN2 from the peripheral blood of a 1-year-old patient using the dox-inducible STEMCCA vector. This patient presented with bacteremia, pneumonia, and neutropenia. Analysis of bone marrow demonstrated normal cellularity with trilineage hematopoiesis and neutropenia.

  5. Effects of yoga practice on muscular endurance in young women.

    Science.gov (United States)

    Shiraishi, Juliana Costa; Bezerra, Lídia Mara Aguiar

    2016-02-01

    The aim of this study was to verify the effects of a systematized yoga practice on muscular endurance in young women. Twenty six women (24 ± 3.5 years old) participated in six weeks of yoga classes, and twenty one women (25 ± 5.1 years old) participated as the control group. The yoga intervention was composed of eighteen sessions, three times per week, at 1 h per session. The muscular endurance of upper limbs (push-up) and abdominal (sit-up) was assessed through the protocol suggested by Gettman (1989) [1] and Golding, Myers and Sinning (1989) [2] to the maximum repetitions performed in 1 min. To verify the significant differences intra groups and between groups a SPANOVA was performed, and the level of significance was p ≤ 0.05. The findings suggest that yoga provides improvement in upper limb and in abdominal muscular endurance.

  6. Responses of dairy heifers to the visual cliff formed by a herringbone milking pit: evidence of fear of heights in cows (Bos taurus).

    Science.gov (United States)

    Arnold, Naomi Adele; Ng, Kim Tee; Jongman, Ellen Caroline; Hemsworth, Paul Hamilton

    2007-11-01

    The ability of cows (Bos taurus) to perceive depth has never been experimentally investigated. If cows can perceive depth, the milking pit in commercial milking facilities may be fear provoking for dairy cows, as past research has shown that most land-dwelling species possess an instinctive fear of heights. In the current study, 12 dairy heifers (1-year-old cows) were exposed to a milking pit (depth-exposed group) and 13 heifers (control group) were exposed to a standard change in the environment while they moved through a milking facility over a 5-day treatment period. Heifers in the depth-exposed group showed a higher heart rate (p fear of heights in cows. Copyright 2007 APA.

  7. Welfare policies and very young children: experimental data on stage-environment fit.

    Science.gov (United States)

    Hill, Heather D; Morris, Pamela

    2008-11-01

    The authors examined the effects of welfare programs that increased maternal employment and family income on the development of very young children using data from 5 random-assignment experiments. The children were 6 months to 3 years old when their mothers entered the programs; cognitive and behavioral outcomes were measured 2-5 years later. While there were no overall program impacts, positive or negative, on the development of children in this age group, there was a pair of domain- and age-specific effects: The programs decreased positive social behavior among 1-year-olds and increased school achievement among 2-year-olds. After exploring several explanations for these results, the authors suggest that the contextual changes engendered by the programs, including children's exposure to center-based child care, interacted differentially with specific developmental transitions.

  8. Decreased body fat, elevated plasma transforming growth factor-β levels, and impaired BMP4-like signaling in biglycan-deficient mice.

    Science.gov (United States)

    Tang, Tao; Thompson, Joel C; Wilson, Patricia G; Nelson, Christina; Williams, Kevin Jon; Tannock, Lisa R

    2013-01-01

    Biglycan (BGN), a small leucine-rich proteoglycan, binds the pro-fibrotic cytokine transforming growth factor β (TGFβ) and inhibits its bioactivity in vitro. Nevertheless, it is controversial whether BGN plays an inhibitory role in vivo. Therefore, the purpose of this study was to evaluate the effect of BGN deficiency on TGFβ activity in vivo by studying 1-year-old Bgn null and wild-type (WT) mice on an Ldlr-null background. Phenotypic and metabolic characterization showed that the Bgn null mice had lower body weight, shorter body length, and shorter femur length (all p kidney histology. Overall, we propose that this unexpected phenotype arises from the effects of BGN deficiency in vivo to elevate TGFβ levels while decreasing bone morphogenetic protein 4-like signaling.

  9. An atypical case of lacrimal sac fistula located on the temporal side of the lateral canthus.

    Science.gov (United States)

    Kim, Gyu-Nam; Huh, Hyun-Do; Park, Jong-Moon; Seo, Seong-Wook

    2012-12-01

    We report a case of congenital lacrimal sac fistula located on the temporal side of the lateral canthus. A systemically healthy 1-year-old girl came to the outpatient clinic with a complaint of tearing on the temporal side of the right lateral canthus since birth. On examination, a small orifice was found in the skin on the temporal side of the lateral canthus. There was no evidence of inflammation or swelling within the opening. Surgeons carried out an operation under general anesthesia. They passed a probe through the lacrimal orifice and advanced it toward the lacrimal sac. Next, they introduced saline to the inferior punctum and found that it drained to the lateral fistula. The lower lid stretched as the dissected fistula was pulled. After the operation, the patient was free of the symptom. This paper is to report a case of congenital lacrimal sac fistula located on the temporal side of the lateral canthus.

  10. Dosimetry of (99m)Tc (DTPA, DMSA and MAG3) used in renal function studies of newborns and children.

    Science.gov (United States)

    Arteaga, Marcial Vásquez; Caballero, Víctor Murillo; Rengifo, Kelman Marín

    2017-07-28

    The dose to kidneys of newborns and 1-year old children was calculated using the MIRD methodology. In order to perform renal studies radiopharmaceutical like (99m)Tc-DTPA, (99m) Tc-MAG3 and (99m)Tc-DMSA are used. Here, besides the anatomic and structure information of kidneys another data are provided in benefit of patient, however during the radioisotope decay emitted radiations delivers, totally or partially, their energy. Therefore is important to estimate the internal radiation dose of the organs. The largest dose to kidneys comes from the self-dose and it is due to the charged particles emitted during (99m)Tc decay. From the three radiopharmaceutical here used the largest dose to kidneys is due to (99m)Tc-DMSA, and the smaller dose is due to (99m)Tc-MAG3. Copyright © 2017 Elsevier Ltd. All rights reserved.

  11. Osteogenesis imperfecta Type IV: a newly identified variant at position c.560 (G > T; p.Gly187Val) in the COL1A2 gene.

    Science.gov (United States)

    Usta, Akin; Karademir, Dilay; Sen, Eylem; Yazici, Selcuk; Adali, Ertan; Erdem, Erkan; Karacan, Meric

    2017-01-01

    Osteogenesis imperfecta is a clinically heterogenous disease caused by defective collagen syntesis associated with a mutation in the COL1A1 or COL1A2 genes. In this report, we present a case of osteogenesis imperfecta (OI) type IV, seen in a female fetus with incurved femurs at 18 weeks of gestation. Molecular analysis of the newborn revealed a novel mutation at position c.560 (c.560 G > T) of the exon 12 in the COL1A2 gene; which lead to the glycine modification with valine (p.Gly187Val) at codon 187. The pregnancy follow-up was uneventful. After delivery, the newborn underwent biphosponat therapy and no fracture was detected until 1 year old.

  12. Feed intake, digestibility, nitrogen utilization, and body weight change of sheep consuming wheat straw supplemented with local agricultural and agro-industrial by-products.

    Science.gov (United States)

    Nurfeta, Ajebu

    2010-06-01

    Effects of supplementing sheep consuming wheat straw with local agro-industrial by-products on feed intake, growth, digestibility and nitrogen utilization were determined. Thirty 1-year-old local wethers, with a mean (+/-SD) live weight of 19.8 (+/-1.06) kg, were assigned to five treatments: wheat straw + atella (T1), wheat straw + atella + poultry litter (T2), wheat straw + atella + coffee pulp (T3), wheat straw + atella + coffee pulp + poultry litter (T4), hay + concentrate (T5). A 7-day digestibility experiment and a 112-day growth trial were conducted. Total dry matter (DM) and organic matter (OM) intake as well as body weight gain was similar for all treatments. The highest (P coffee pulp are available, smallholder farmers could feed the mixtures as a supplement to straw with a good performance without using concentrate feeds.

  13. EXPERIENCE OF IMPLEMENTATION OF THE COHORT PNEUMOCOCCAL VACCINATION PROGRAM FOR INFANTS IN ST. PETERSBURG

    Directory of Open Access Journals (Sweden)

    S. M. Kharit

    2014-01-01

    Full Text Available The program of cohort immunization of 0-1-year-old children with a pneumococcal conjugate vaccine (PCV has been going on in Saint Petersburg with the help of the Rostropovich‑Vishnevskaya Foundation since June 2013. The need in cohort immunization against pneumococcal infection is substantiated by effectiveness of use of PCVs in previous years, when immunization therewith resulted in 9.5-fold and 1.8-fold reduction in the incidence rate of community-acquired pneumonias and acute otites mediae, respectively, at pediatric institutions. The joint program involved use of PCV13. 38,000 vaccinal doses confirm high safety thereof both for separate and combined administration. The article provides analysis of vaccination organization and demonstrates importance of individual work with the population and training of all medical professionals.

  14. Aortic stenosis with abnormal eccentric left ventricular remodeling secondary to hypothyroidism in a Bourdeaux Mastiff

    Directory of Open Access Journals (Sweden)

    Guilherme Augusto Minozzo

    Full Text Available ABSTRACT: This paper describes a case of congenital aortic stenosis with eccentric left ventricular hypertrophy associated with hypothyroidism in a 1-year-old Bourdeaux Mastiff dog. The dog had ascites, apathy, alopecic and erythematous skin lesions in different parts of the body. A two-dimensional echocardiogram revealed aortic valve stenosis, with poststenotic dilation in the ascending aorta. The same exam showed eccentric hypertrophy and dilation of the left ventricle during systole and diastole. Aortic stenosis usually results in concentric left ventricular hypertrophy instead of eccentric hypertrophy; and therefore, this finding was very unusual. Hypothyroidism, which is uncommon in young dogs, may be incriminated as the cause of ventricular dilation, making this report even more interesting. Because hypothyroidism would only result in dilatation, the eccentric hypertrophy was attributed to pressure overload caused by aortic stenosis. Thus, cardiac alterations of this case represent a paradoxical association of both diseases.

  15. Differentiated effect of ageing on the enzymes of Krebs' cycle, electron transfer complexes and glutamate metabolism of non-synaptic and intra-synaptic mitochondria from cerebral cortex.

    Science.gov (United States)

    Villa, R F; Gorini, A; Hoyer, S

    2006-11-01

    The effect of ageing on the activity of enzymes linked to Krebs' cycle, electron transfer chain and glutamate metabolism was studied in three different types of mitochondria of cerebral cortex of 1-year old and 2-year old male Wistar rats. We assessed the maximum rate (V(max)) of the mitochondrial enzyme activities in non-synaptic perikaryal mitochondria, and in two populations of intra-synaptic mitochondria. The results indicated that: (i) in normal, steady-state cerebral cortex the values of the catalytic activities of the enzymes markedly differed in the various populations of mitochondria; (ii) in intra-synaptic mitochondria, ageing affected the catalytic properties of the enzymes linked to Krebs' cycle, electron transfer chain and glutamate metabolism; (iii) these changes were more evident in intra-synaptic "heavy" than "light" mitochondria. These results indicate a different age-related vulnerability of subpopulations of mitochondria in vivo located into synapses than non-synaptic ones.

  16. Nocardia infection in a renal transplant recipient

    Directory of Open Access Journals (Sweden)

    K K Kaswan

    2011-01-01

    Full Text Available Opportunistic infection occurs in up to 20% renal transplant patients and is associated with a high mortality. We report a 47-year-old diabetic female with 1-year-old deceased donor renal allograft on triple drug immunosuppression. She developed cytomegalovirus retinitis at ten months post-transplant followed by nocardiasis manifested by hemiparesis with comatose state due to lumbar epidural and multiple brain abscesses, in spite of immediately curtailing immunosuppression. She recovered with linezolid and cotrimoxazole and was discharged two weeks later. She is maintaining stable graft function with serum creatinine 1.4 mg/dL on cyclosporin 2.5 mg/kg/day and prednisone10 mg/day with maintenance therapy for nocardiasis.

  17. Temperament, stereotypies and anticipatory behaviour as measures of welfare in mink

    DEFF Research Database (Denmark)

    Hansen, Steffen W.; Jeppesen, Leif Lau

    2006-01-01

    as a measure of poor welfare. On this basis, it was interesting to see if the sensitivity to a reward as expressed by the level of anticipatory behaviour of high and low stereotyping mink would clarify the discrepancy between the two classical measures of welfare. Twenty-four of the most stereotyping animals...... and 24 of the non-stereotyping animals were selected and exposed to Pavlovian conditioning with both positive and negative rewards. Their behaviour during anticipation of the reward changed, however, they also showed a great variation and dependence on feeding time as well as stereotypy status. So......A farm mink population of 290 1-year-old wild-coloured females was scanned for stereotyped behaviour in October 2003. At the same time the temperament of the individuals was established with a stick test. Some of the females performed no stereotypies in 54 scans and this fraction of the population...

  18. Ophthalmomyiasis interna anterior in a dog: keratotomy and extraction of a Cuterebra sp. larva.

    Science.gov (United States)

    Edelmann, Michele L; Lucio-Forster, Araceli; Kern, Thomas J; Bowman, Dwight D; Ledbetter, Eric C

    2014-11-01

    A 1-year-old female spayed mixed-breed dog was presented for evaluation of acute onset of lethargy and blepharospasm OD. Slit-lamp biomicroscopy revealed a segmented larva embedded in the inferonasal iris. Moderate anterior uveitis was present. After pharmacologic dilation, mild vitreal hemorrhage and chorioretinal migration tracks were identified. The dog was treated empirically for uveitis for 5 days, after which a keratotomy and larval foreign body extraction was performed. The dog recovered uneventfully from intraocular surgery and remained visual and comfortable. Parasite evaluation confirmed the larva to be a Cuterebra sp. To the authors' knowledge, this is the first report of canine ophthalmomyiasis interna anterior, and the first report of successful surgical removal from the anterior segment in a dog with preservation of vision.

  19. Height, weight and body mass index in early adulthood and risk of schizophrenia

    DEFF Research Database (Denmark)

    2006-01-01

    status when the cohort members were 1 year old, birth weight, birth length, and maternal pre-pregnancy BMI. RESULTS: Forty-five cases of schizophrenia had a lower young adult mean body weight and BMI than controls. A significant inverse relationship between BMI and risk of later schizophrenia was found....... No significant differences between cases and controls were observed with respect to adult height. CONCLUSION: Independent of several possible confounders, an inverse relationship between young adult BMI and risk of later development of schizophrenia was demonstrated in this all-male sample.......OBJECTIVE: To illuminate the possible associations between height, weight, and body mass index (BMI) during early adulthood and the development of schizophrenia. METHOD: This prospective study is based on an all-male sample of 3210 individuals from the Copenhagen Perinatal Cohort, comprising...

  20. Feline Unilateral Uterine Prolapse: A Description of Two Cases

    Directory of Open Access Journals (Sweden)

    Ahmet SABUNCU

    2017-01-01

    Full Text Available Two 1-year old primiparous cats were referred to the Small Animal Clinic of Department of Obstetrics and Gynaecology, Faculty of Veterinary Medicine, Istanbul University two weeks apart with a protrusion of a mass through vagina. Depending on clinical and ultrasonographic findings, unilateral uterine prolapse was diagnosed in both of the cats. Uterine prolapse was occured just after the last delivery in Case 1, and was occured 3 days after parturition in Case 2. Ovariohysterectomy was performed following manual reduction and intra-abdominal retraction of the prolapsed tissue in both cats. According to the author’s knowledge, this is the first report of uterine prolapse in a cat 3 days after parturition.

  1. Phonetic description of babbling in Danish toddlers born with and without unilateral cleft lip and palate

    DEFF Research Database (Denmark)

    Willadsen, Elisabeth; Albrechstn, Helle

    2006-01-01

    Objective: To investigate prelinguistic vocalization sequences of 1-year-old children with and without cleft lip and palate. Design: Prospective study. Participants: Thirty-eight children born with unilateral cleft lip and palate and 36 control children born without clefts. The cleft children had...... the lip, soft palate, and posterior part of the hard palate repaired at 4 months of age. The lip was closed ad modum Millard, the nose was corrected according to McComb, and the soft palate was closed with a posteriorly based vomer flap. Methods: Data were obtained from a clinical visit during which...... the canonical babbling stage. Results: No significant differences were observed between the cleft and control groups concerning frequency of occurrence of vocalization sequences, contoids, or vocoids. Structural differences between the groups seem to influence the contoid inventory, with a higher frequency...

  2. Studies on the mechanism of long term survival of Taenia taeniaeformis in rats.

    Science.gov (United States)

    Kwa, B H; Liew, F Y

    1978-03-01

    An attempt was made to determine if blocking antibody is involved in protecting cysticerci of Taenia taeniaeformis against a host immune response. Immunoflourescence microscopy confirmed that host antibody is presnet on the parasite surface within the capsule. To test if the larvae can still survive after such a coat of blocking antibody is removed, the larvae were trysinised and then implanted into recipients. The results indicate that blocking antibody could be involved in the survival of 1 year old established larvae. Untrypsinised larvae were normal 14 days after implantation into control or immunised rats. Trypsinised larvae implanted in control rats were alive but showed on intense cell adherence on their surface. On the other hand, trypsinised larvae implanted into immunised rats were dead and completely encapsulated. However, experiments with 1 month old larvae were inconclusive.

  3. Clinical study of cutaneous drug eruptions in 200 patients

    Directory of Open Access Journals (Sweden)

    Raksha M

    2008-01-01

    Full Text Available Two hundred patients (112 males and 88 females with cutaneous drug eruption were studied. The aim was to recognize the offending drug, to evaluate mortality and morbidity, educate the patient and avoid self-administration and readministration of drugs. Fixed drug eruption was the commonest reaction, seen in 61 patients; other reactions being urticaria and angioedema, morbilliform rash in 37, pruritus in 25, Stevens Johnson Syndrome (SJS in 6, purpura in 6, exfoliative dermatitis in 5, photosensitivity in 5, toxic epidermal necrolysis in 2, acneiform eruption in 3, erythema multiforme in 2. Maximum patients belonged to the age group 41-50, followed by 21-30 and 31-40 years. The youngest was 1 year old and the oldest was 80 years old. Period of development of lesion after intake of drug varied from 1 day to 45 days. Cotrimoxazole was the commonest drug, in 26 cases; followed by Ibuprofen in 20 cases.

  4. Forest age stands affect soil respiration and litterfall in a Black pine forest managed by a shelterwood system in the Central Spain?

    Science.gov (United States)

    Hedo de Santiago, Javier; Borja, Manuel Esteban Lucas; Candel, David; Viñegla Pérez, Benjamin

    2016-04-01

    This study aims to investigate the effects that stand age and forest structure generates on soil respiration and litterfall quantity. The effect of stand age on these variables was studied in a shelterwood system Spanish Black pine chronosequence in central Iberian Peninsula composed of 0-20, 20-40, 40-60, 60-80, 80-100-year-old. For each stand age, six forest stands with similar characteristics of soil type and site preparation were used. Also, a forest area ranging 80-120 years old and without forest intervention was selected and used as control. We also measured organic matter, C:N ratio, soil moisture and pH in the top 10 mineral soil at each compartment. Soil respiration measurements were carried out in three time points (3, 8 and 12 days). Results showed a clear trend in soil respiration, comparing all the experimental areas. Soil respiration showed the same trend in all stands. It initially showed higher rates, reaching stability in the middle of the measurement process and finally lightly increasing the respiration rate. The older stands had significantly higher soil respiration than the younger stands. Soil organic matter values were also higher in the more mature stands. C:N ratio showed the opposite trend, showing lower values in the less mature stands. More mature stands clearly showed more quantity of litterfall than the younger ones and there was a positive correlation between soil respiration and litterfall. Finally, the multivariate PCA analysis clearly clustered three differenced groups: Control plot; from 100 to 40 years old and from 39 to 1 years old, taking into account both soil respiration and litterfall quantity, also separately. Our results suggest that the control plot has a better soil quality and that extreme forest stand ages (100-80 and 19-1 years old) and the associated forest structure generates differences in soil respiration.

  5. Alteration of foliar flavonoid chemistry induced by enhanced UV-B radiation in field-grown Pinus ponderosa, Quercus rubra and Pseudotsuga menziesii.

    Science.gov (United States)

    Warren, Jeffrey M; Bassman, John H; Mattinson, D Scott; Fellman, John K; Edwards, Gerald E; Robberecht, Ronald

    2002-03-01

    Chromatographic analyses of foliage from several tree species illustrate the species-specific effects of UV-B radiation on both quantity and composition of foliar flavonoids. Pinus ponderosa, Quercus rubra and Pseudotsuga menziesii were field-grown under modulated ambient (1x) and enhanced (2x) biologically effective UV-B radiation. Foliage was harvested seasonally over a 3-year period, extracted, purified and the flavonoid fraction applied to a mu Bondapak/C(18) column HPLC system sampling at 254 nm. Total flavonoid concentrations in Quercus rubra foliage were more than twice (leaf area basis) that of the other species; Pseudotsuga menziesii foliage had intermediate levels and P. ponderosa had the lowest concentrations of total flavonoids. No statistically significant UV-B radiation-induced effects were found in total foliar flavonoid concentrations for any species; however, concentrations of specific compounds within each species exhibited significant treatment effects. Higher (but statistically insignificant) levels of flavonoids were induced by UV-B irradiation in 1- and 2-year-old P. ponderosa foliage. Total flavonoid concentrations in 2-year-old needles increased by 50% (1x ambient UV-B radiation) or 70% (2x ambient UV-B radiation) from that of 1-year-old tissue. Foliar flavonoids of Q. rubra under enhanced UV-B radiation tended to shift from early-eluting compounds to less polar flavonoids eluting later. There were no clear patterns of UV-B radiation effects on 1-year-old P. menziesii foliage. However, 2-year-old tissue had slightly higher foliar flavonoids under the 2x UV-B radiation treatment compared to ambient levels. Results suggest that enhanced UV-B radiation will alter foliar flavonoid composition and concentrations in forest tree species, which could impact tissue protection, and ultimately, competition, herbivory or litter decomposition.

  6. Comparative analysis of early and middle outcomes of the arterial switch operation in children with complete transposition of the great arteries with ventricular septal defect and severe pulmonary artery hypertension

    Institute of Scientific and Technical Information of China (English)

    LIU Cheng-hu; SU Jun-wu; LI Zhi-qiang; FAN Xiang-ming; CHEN Yan; HE Yan; LIU Ying-long

    2013-01-01

    Background The best age for the arterial switch operation (ASO) in complete transposition of great arteries with ventricular septal defect is usually considered to be within six months.This is because of severe pulmonary arterial hypertension and pulmonary arterial obstructive pathological changes.There are few reports on ASO surgery in children older than three years old.Methods We studied 41 children,including 24 males and 17 females,from January 2010 to December 2011.They were divided into three groups by operation age; 15 patients were <1 year old,13 were 1-3 years old,and 13 were >3 years old.Associated cardiac abnormalities included patent ductus arteriosus in six cases,atrial septal defect in five cases,and mitral regurgitation in two cases.All the patients had echocardiography before the operation.Seventeen patients underwent a coronary computed tomography examination and five patients underwent right heart catheterization.All ASO surgeries were performed under inhalation anesthesia and hypothermic cardiopulmonary bypass.Results Three operative deaths occurred.Two were in the <1 year old group,who died from severe postoperative low cardiac output.The other was two years old and died of postoperative multiple organ failure.There was no significant difference in postoperative mortality and the recent mid-term survival rate among the three groups.Thirty-eight cases were followed up for an average of 11.2 months,ranging 6-20 months.One seven years old patient died of acute diarrhea and electrolyte disturbance arrhythmia caused by food poisoning.Three patients more than three years old still had residual pulmonary arterial hypertension.Conclusion Children older than three years old can still undergo the ASO procedure,but residual pulmonary hypertension is present.

  7. Changes in the essential oil composition in the needles of Scots pine (Pinus sylvestris L.) under anthropogenic stress.

    Science.gov (United States)

    Judzentiene, Asta; Stikliene, Aida; Kupcinskiene, Eugenija

    2007-03-21

    Unfavorable anthropogenic factors, such as air pollution, lead to biochemical responses in trees. Changes in the amounts of secondary metabolites may be early indicators of invisible injuries. The aim of this study was to evaluate composition of the essential oils in the needles of Scots pine (Pinus sylvestris L.) growing in the areas affected by pollutant emissions of main factories in Lithuania: a nitrogen fertilizer factory (NFF), a cement factory (CF), and an oil refinery (OR). Totally, 14 pine stands were examined along transects from the factories (July 2005). Volatile components of the needles were extracted and analyzed by GC and GC/MS. Over 70 components of the essential oils were identified in current-year and 1-year-old needles. Along the CF transect for current-year needles, the percentage of diterpenes was decreasing with the increasing pH of the pine bark (r = -0.582; p us to distinguish the most contrasting stands according to the concentration of air pollutants. Current-year needles were more effective as indicators of the effects of pollution than 1-year-old needles in the case of the NFF and the OR transects, and both-aged needles were equally valuable in the case of the CF transect. The changes detected in the proportions of components of the essential oils in the needles of the trees affected by the industrial emissions may play a significant role in modifying the susceptibility of the pine stands to the biotic factors, and also may alter emissions of terpenes from the stands to the atmosphere.

  8. Ethylene Evolution Changes in Tilted Fraxinus mandshurica Rupr. var. japonica Maxim. Seedlings in Relation to Tension Wood Formation

    Institute of Scientific and Technical Information of China (English)

    Sha Jiang; Ke Xu; Na Zhao; Shu-Xin Zheng; Yan-Ping Ren; Yu-Bao Gao; Song Gu

    2009-01-01

    The effects of ethylene on tension wood formation were studied in 3-year-old Fraxinus mandshurica Rupr. var. japonica Maxim, seedlings in two separate experiments. In experiment 1, ethylene evolution of buds and stems was measured using gas chromatography after 0, 2,4, 7,14, and 21 d of treatment; in experiment 2, both aminoethoxyvinylglycine (AVG) and AgNO3 were applied to the horizontally-placed stems, and the cell numbers on sites of applications were measured after 40 d. Ethylene evolution from buds was found to be much greater in tilted seedlings than in upright ones. The cell numbers of wood fibers in shoots and 1-year-old stems were reduced in treatments with 12.5 x 10-7 μmol/L AVG, 12.5 x 10-8 μmol/L AVG, and 11.8 x 10-8 μmol/L AgNO3; whereas the horizontal and vertical diameters were reduced by treatment of 12.5 x 10-7 μnol/L AVG. Ethylene evolutions of shoots and 1-year-old stems were inhibited greatly in comparison with the control by applying 12.5 x 10-7 μmol/L AVG. The formation of a gelatinous layer of wood fibers was affected by neither AVG nor AgNO3 application. These results suggest that ethylene regulates the quantity of wood production, but does not affect G-layer formation in F. mandshurica Rupr. var. japonica Maxim, seedlings.

  9. [Efficacy and safety profile of cranberry in infants and children with recurrent urinary tract infection].

    Science.gov (United States)

    Fernández-Puentes, V; Uberos, J; Rodríguez-Belmonte, R; Nogueras-Ocaña, M; Blanca-Jover, E; Narbona-López, E

    2015-06-01

    Cranberry prophylaxis of recurrent urinary tract infection in infants has proven effective in the experimental model of the adult. There are few data on its efficacy, safety and recommended dose in the pediatric population. A controlled, double-blind Phase III clinical trial was conducted on children older than 1 month of age to evaluate the efficacy and safety of cranberry in recurrent urinary tract infection. The assumption was of the non-inferiority of cranberry versus trimethoprim. Statistical analysis was performed using Kaplan Meier analysis. A total of 85 patients under 1 year of age and 107 over 1 year were recruited. Trimethoprim was prescribed to 75 patients and 117 received cranberry. The cumulative rate of urinary infection associated with cranberry prophylaxis in children under 1 year was 46% (95% CI; 23-70) in children and 17% (95% CI; 0-38) in girls, effectively at doses inferior to trimethoprim. In children over 1 year-old cranberry was not inferior to trimethoprim, with a cumulative rate of urine infection of 26% (95% CI; 12-41). The cranberry was well tolerated and with no new adverse effects. Our study confirms that cranberry is safe and effective in the prophylaxis of recurrent urinary tract infection in infants and children. With the doses used, their efficiency is not less than that observed for trimethoprim among those over 1 year-old. (Clinical Trials Registry ISRCTN16968287). Copyright © 2014 Asociación Española de Pediatría. Published by Elsevier España, S.L.U. All rights reserved.

  10. Early social cognition in three cultural contexts.

    Science.gov (United States)

    Callaghan, Tara; Moll, Henrike; Rakoczy, Hannes; Warneken, Felix; Liszkowski, Ulf; Behne, Tanya; Tomasello, Michael

    2011-08-01

    The influence of culture on cognitive development is well established for school age and older children. But almost nothing is known about how different parenting and socialization practices in different cultures affect infants' and young children's earliest emerging cognitive and social-cognitive skills. In the current monograph, we report a series of eight studies in which we systematically assessed the social-cognitive skills of 1- to 3-year-old children in three diverse cultural settings. One group of children was from a Western, middle-class cultural setting in rural Canada and the other two groups were from traditional, small-scale cultural settings in rural Peru and India.In a first group of studies, we assessed 1-year-old children's most basic social-cognitive skills for understanding the intentions and attention of others: imitation, helping, gaze following, and communicative pointing.Children's performance in these tasks was mostly similar across cultural settings. In a second group of studies, we assessed 1-year-old children's skills in participating in interactive episodes of collaboration and joint attention.Again in these studies the general finding was one of cross-cultural similarity. In a final pair of studies, we assessed 2- to 3-year-old children's skills within two symbolic systems (pretense and pictorial). Here we found that the Canadian children who had much more experience with such symbols showed skills at an earlier age.Our overall conclusion is that young children in all cultural settings get sufficient amounts of the right kinds of social experience to develop their most basic social-cognitive skills for interacting with others and participating in culture at around the same age. In contrast, children's acquisition of more culturally specific skills for use in practices involving artifacts and symbols is more dependent on specific learning experiences.

  11. Recruitment in a Colorado population of big brown bats: Breeding probabilities, litter size, and first-year survival

    Science.gov (United States)

    O'Shea, T.J.; Ellison, L.E.; Neubaum, D.J.; Neubaum, M.A.; Reynolds, C.A.; Bowen, R.A.

    2010-01-01

    We used markrecapture estimation techniques and radiography to test hypotheses about 3 important aspects of recruitment in big brown bats (Eptesicus fuscus) in Fort Collins, Colorado: adult breeding probabilities, litter size, and 1st-year survival of young. We marked 2,968 females with passive integrated transponder (PIT) tags at multiple sites during 2001-2005 and based our assessments on direct recaptures (breeding probabilities) and passive detection with automated PIT tag readers (1st-year survival). We interpreted our data in relation to hypotheses regarding demographic influences of bat age, roost, and effects of years with unusual environmental conditions: extreme drought (2002) and arrival of a West Nile virus epizootic (2003). Conditional breeding probabilities at 6 roosts sampled in 2002-2005 were estimated as 0.64 (95% confidence interval [95% CI] = 0.530.73) in 1-year-old females, but were consistently high (95% CI = 0.940.96) and did not vary by roost, year, or prior year breeding status in older adults. Mean litter size was 1.11 (95% CI = 1.051.17), based on examination of 112 pregnant females by radiography. Litter size was not higher in older or larger females and was similar to results of other studies in western North America despite wide variation in latitude. First-year survival was estimated as 0.67 (95% CI = 0.610.73) for weaned females at 5 maternity roosts over 5 consecutive years, was lower than adult survival (0.79; 95% CI = 0.770.81), and varied by roost. Based on model selection criteria, strong evidence exists for complex roost and year effects on 1st-year survival. First-year survival was lowest in bats born during the drought year. Juvenile females that did not return to roosts as 1-year-olds had lower body condition indices in late summer of their natal year than those known to survive. ?? 2009 American Society of Mammalogists.

  12. ANTICORPOS ANTI-Toxoplasma gondii EM CARRAPATOS NO MUNICÍPIO DE GOIÂNIA: LEVANTAMENTO SOROLÓGICO ANTIBODIES ANTI - Toxoplasma gondii IN GOATS IN THE AREA OF GOIÂNIA: SOROLOGICAL SURVEY

    Directory of Open Access Journals (Sweden)

    Guido Fontgalland Coelho Linhares

    2007-09-01

    Full Text Available

    Foi efetuado estudo sorológico para pesquisa de anticorpos anti-Toxoplasma gondii pelo método de hemaglutinação indireta em 109 (cento e nove amostras de soro de caprinos provenientes de 5 (cinco rebanhos distintos do município de Goiânia. Foi encontrado 30,2% de animais positivos com idade inferior a um ano de idade, e 51,5% em animais com idade superior a um ano de idade. Com relação ao sexo, 46,3% das fêmeas foram positivas, enquanto que os machos 33,3%. E finalmente 43,1% quando foram testados os animais de ambos os sexos, exceto os lactantes. O titulo mínimo considerado foi 1/64.

    Studies on prevalence of anti-Toxoplasma gondii antibodies was carried out by the indirect hemaglutination test in 109 caprine sera samples from five distinct heards in Goiânia, Goiás. It had been shown positivity of 30.2% for animals under 1 year old and 51.5% for animals over 1 year old. Between females 46.3% were positive and males 33.3%. And finally 43.1% among animals of both sexes and any age, except lactents. The sera were tested from the inicial dilutron of 1/64.

  13. Infant Mortality Risk and Paternity Certainty Are Associated with Postnatal Maternal Behavior toward Adult Male Mountain Gorillas (Gorilla beringei beringei.

    Directory of Open Access Journals (Sweden)

    Stacy Rosenbaum

    Full Text Available Sexually selected infanticide is an important source of infant mortality in many mammalian species. In species with long-term male-female associations, females may benefit from male protection against infanticidal outsiders. We tested whether mountain gorilla (Gorilla beringei beringei mothers in single and multi-male groups monitored by the Dian Fossey Gorilla Fund's Karisoke Research Center actively facilitated interactions between their infants and a potentially protective male. We also evaluated the criteria mothers in multi-male groups used to choose a preferred male social partner. In single male groups, where infanticide risk and paternity certainty are high, females with infants <1 year old spent more time near and affiliated more with males than females without young infants. In multi-male groups, where infanticide rates and paternity certainty are lower, mothers with new infants exhibited few behavioral changes toward males. The sole notable change was that females with young infants proportionally increased their time near males they previously spent little time near when compared to males they had previously preferred, perhaps to encourage paternity uncertainty and deter aggression. Rank was a much better predictor of females' social partner choice than paternity. Older infants (2-3 years in multi-male groups mirrored their mothers' preferences for individual male social partners; 89% spent the most time in close proximity to the male their mother had spent the most time near when they were <1 year old. Observed discrepancies between female behavior in single and multi-male groups likely reflect different levels of postpartum intersexual conflict; in groups where paternity certainty and infanticide risk are both high, male-female interests align and females behave accordingly. This highlights the importance of considering individual and group-level variation when evaluating intersexual conflict across the reproductive cycle.

  14. Infant Mortality Risk and Paternity Certainty Are Associated with Postnatal Maternal Behavior toward Adult Male Mountain Gorillas (Gorilla beringei beringei).

    Science.gov (United States)

    Rosenbaum, Stacy; Hirwa, Jean Paul; Silk, Joan B; Vigilant, Linda; Stoinski, Tara S

    2016-01-01

    Sexually selected infanticide is an important source of infant mortality in many mammalian species. In species with long-term male-female associations, females may benefit from male protection against infanticidal outsiders. We tested whether mountain gorilla (Gorilla beringei beringei) mothers in single and multi-male groups monitored by the Dian Fossey Gorilla Fund's Karisoke Research Center actively facilitated interactions between their infants and a potentially protective male. We also evaluated the criteria mothers in multi-male groups used to choose a preferred male social partner. In single male groups, where infanticide risk and paternity certainty are high, females with infants <1 year old spent more time near and affiliated more with males than females without young infants. In multi-male groups, where infanticide rates and paternity certainty are lower, mothers with new infants exhibited few behavioral changes toward males. The sole notable change was that females with young infants proportionally increased their time near males they previously spent little time near when compared to males they had previously preferred, perhaps to encourage paternity uncertainty and deter aggression. Rank was a much better predictor of females' social partner choice than paternity. Older infants (2-3 years) in multi-male groups mirrored their mothers' preferences for individual male social partners; 89% spent the most time in close proximity to the male their mother had spent the most time near when they were <1 year old. Observed discrepancies between female behavior in single and multi-male groups likely reflect different levels of postpartum intersexual conflict; in groups where paternity certainty and infanticide risk are both high, male-female interests align and females behave accordingly. This highlights the importance of considering individual and group-level variation when evaluating intersexual conflict across the reproductive cycle.

  15. To Explore the Clinical Nutritional Iron Deficiency Anemia of Infantile%小儿营养性缺铁性贫血的临床分析

    Institute of Scientific and Technical Information of China (English)

    田秀华

    2015-01-01

    Objective To analyze nutritional iron deficiency anemia of infantile.Methods Selected 90 cases nutritional iron deficiency anemia of infantile with clinical data retrospective summary, analysis the clinical characteristics and related risk factors. Results 61.11% of nutritional iron deifciency anemia children at age 7 months to 1 year old, Rural children more than city children, exclusive breastfeeding not add side dish was susceptible to ischemic anemia.Conclusion 7 months to 1 year old belongs to infantile nutritional iron deifciency anemia intensiifes period, prevention timely, diagnosis, treatment and reduce the incidence of the disease.%目的:分析小儿营养缺铁性贫血情况。方法回顾性总结90例小儿营养缺铁性贫血患者临床资料,分析其临床发病特点和相关危险因素。结果61.11%儿童营养缺铁性贫血年龄为7个月~1岁;农村儿童多于城市儿童;纯母乳喂养未添加辅食儿童易患缺血性贫血。结论7个月~1岁属于小儿营养缺铁性贫血高发期,应该及时预防、诊断、治疗,降低该病发生率。

  16. 17α-Ethinylestradiol (EE2) treatment of wild roach (Rutilus rutilus) during early life development disrupts expression of genes directly involved in the feedback cycle of estrogen.

    Science.gov (United States)

    Nikoleris, Lina; Hultin, Cecilia L; Hallgren, Per; Hansson, Maria C

    2016-02-01

    Fish are more sensitive to introduced disturbances from synthetic endocrine disrupting compounds during early life phases compared with mature stages. 17α-Ethinylestradiol (EE2), which is the active compound in human oral contraceptives and hormone replacement therapies, is today ever present in the effluents from sewage treatment plants. EE2 targets and interacts with the endogenous biological systems of exposed vertebrates resulting in to large extents unknown short- and long-term effects. We investigated how EE2 exposure affects expression profiles of a large number of target genes during early life of roach (Rutilus rutilus). We exposed fertilized roach eggs collected from a lake in Southern Sweden to EE2 for 12weeks together with 1+-year-old roach in aquaria. We measured the gene expression of the estrogen receptor (esr)1/2a/2b, androgen receptor (ar), vitellogenin, cytochrome P450 (cyp)19a1a/1b in fertilized eggs; newly hatched larvae; 12-week-old fry; and juvenile wild roach (1+-year-old). Results shows that an EE2 concentration as low as 0.5ng/L significantly affects gene expression during early development. Gene expression responses vary both among life stages and molecular receptors. We also show that the gene profile of the estrogen feedback cycle to a large extent depends on the relationship between the three esr genes and the two cyp19a1 genes, which are all up-regulated with age. Results indicate that a disruption of the natural activity of the dominant esr gene could lead to detrimental biological effects if EE2 exposure occurs during development, even if this exposure occurred for only a short period.

  17. The Effects of Run-of-River Hydroelectric Power Schemes on Fish Community Composition in Temperate Streams and Rivers.

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    Gary S Bilotta

    Full Text Available The potential environmental impacts of large-scale storage hydroelectric power (HEP schemes have been well-documented in the literature. In Europe, awareness of these potential impacts and limited opportunities for politically-acceptable medium- to large-scale schemes, have caused attention to focus on smaller-scale HEP schemes, particularly run-of-river (ROR schemes, to contribute to meeting renewable energy targets. Run-of-river HEP schemes are often presumed to be less environmentally damaging than large-scale storage HEP schemes. However, there is currently a lack of peer-reviewed studies on their physical and ecological impact. The aim of this article was to investigate the effects of ROR HEP schemes on communities of fish in temperate streams and rivers, using a Before-After, Control-Impact (BACI study design. The study makes use of routine environmental surveillance data collected as part of long-term national and international monitoring programmes at 23 systematically-selected ROR HEP schemes and 23 systematically-selected paired control sites. Six area-normalised metrics of fish community composition were analysed using a linear mixed effects model (number of species, number of fish, number of Atlantic salmon-Salmo salar, number of >1 year old Atlantic salmon, number of brown trout-Salmo trutta, and number of >1 year old brown trout. The analyses showed that there was a statistically significant effect (p<0.05 of ROR HEP construction and operation on the number of species. However, no statistically significant effects were detected on the other five metrics of community composition. The implications of these findings are discussed in this article and recommendations are made for best-practice study design for future fish community impact studies.

  18. A segmental radiological study of the spine and rib – cage in children with progressive Infantile Idiopathic Scoliosis

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    Vasiliadis Elias S

    2006-10-01

    Full Text Available Abstract Background The role of rib cage in the development of progressive infantile idiopathic scoliosis (IIS has not been studied previously. No report was found for rib growth in children with IIS. These findings caused us to undertake a segmental radiological study of the spine and rib-cage in children with progressive IIS. The aim of the present study is to present a new method for assessing the thoracic shape in scoliotics and in control subjects and to compare the findings between the two groups. Materials and methods In the posteroanterior (PA spinal radiographs of 24 patients with progressive IIS, with a mean age of 4.1 years old, the Thoracic Ratios (TRs (segmental convex and concave TRs, the Cobb angle, the segmental vertebral rotation and vertebral tilt were measured. In 233 subjects, with a mean age of 5.1 years old, who were used as a control group, the segmental left and right TRs and the total width of the chest (left plus right TRs were measured in PA chest radiographs. Statistical analysis included Mann-Whitney, Spearman correlation coefficient, multiple linear regression analysis and ANOVA. Results The comparison shows that the scoliotic thorax is significantly narrower than that of the controls at all spinal levels. The upper chest in IIS is funnel-shaped and the vertebral rotation at T4 early in management correlates significantly with the apical vertebral rotation at follow up. Conclusion The IIS thorax is narrower than that of the controls, the upper chest is funnel-shaped and there is a predictive value of vertebral rotation at the upper limit of the thoracic curve of IIS, which reflects, impaired rib control of spinal rotation possibly due to neuromuscular factors, which contribute also to the funnel-shaped chest.

  19. Sulfadiazine uptake and effects in common hazel (Corylus avellana L.).

    Science.gov (United States)

    Michelini, Lucia; Meggio, Franco; Reichel, Rüdiger; Thiele-Bruhn, Sören; Pitacco, Andrea; Scattolin, Linda; Montecchio, Lucio; Alberghini, Sara; Squartini, Andrea; Ghisi, Rossella

    2015-09-01

    Soil contamination by antibiotics is a possible consequence of animal husbandry waste, sewage sludge, and reclaimed water spreading in agriculture. In this study, 1-year-old hazel plants (Corylus avellana L.) were grown in pots for 64 days in soil spiked with sulfadiazine (SDZ) in the range 0.01-100 mg kg(-1) soil. Leaf gas exchanges, fluorescence parameters and plant growth were measured regularly during the experiment, whereas plant biomass, sulfonamide concentrations in soil and plant tissues, and the quantitative variation of culturable bacterial endophytes in leaf petiole were analyzed at the end of the trial. During the experiment, photosynthesis and leaf transpiration as well as fluorescence parameters were progressively reduced by the antibiotic. Effects were more evident for leaf transpiration and for the highest SDZ spiking concentrations, whereas growth analyses did not reveal negative effects of the antibiotic. At the end of the trial, a high number of culturable endophytic bacteria in the leaf petiole of plants treated with 0.1 and 0.01 mg kg(-1) were observed, and SDZ was extractable from soil and plant roots for spiking concentrations ≥1 mg kg(-1). Inside plants, the antibiotic was mainly stored at the root level with bioconcentration factors increasing with the spiking dose, and the hydroxylated derivate 4-OH-SDZ was the only metabolite detected. Overall results show that 1-year-old hazel plants can contribute to the reduction of sulfonamide concentrations in the environment, however, sensitive reactions to SDZ can be expected at the highest contamination levels.

  20. Human exposure to trace elements through the skin by direct contact with clothing: Risk assessment

    Energy Technology Data Exchange (ETDEWEB)

    Rovira, Joaquim [Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Universitat Rovira i Virgili, Sant Llorenç 21, 43201 Reus, Catalonia (Spain); Environmental Engineering Laboratory, Departament d' Enginyeria Quimica, Universitat Rovira i Virgili, Av. Països Catalans 26, 43007 Tarragona, Catalonia (Spain); Nadal, Martí [Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Universitat Rovira i Virgili, Sant Llorenç 21, 43201 Reus, Catalonia (Spain); Schuhmacher, Marta [Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Universitat Rovira i Virgili, Sant Llorenç 21, 43201 Reus, Catalonia (Spain); Environmental Engineering Laboratory, Departament d' Enginyeria Quimica, Universitat Rovira i Virgili, Av. Països Catalans 26, 43007 Tarragona, Catalonia (Spain); Domingo, José L., E-mail: joseluis.domingo@urv.cat [Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, Universitat Rovira i Virgili, Sant Llorenç 21, 43201 Reus, Catalonia (Spain)

    2015-07-15

    Metals in textile products and clothing are used for many purposes, such as metal complex dyes, pigments, mordant, catalyst in synthetic fabrics manufacture, synergists of flame retardants, antimicrobials, or as water repellents and odour-preventive agents. When present in textile materials, heavy metals may mean a potential danger to human health. In the present study, the concentrations of a number of elements (Al, As, B, Ba, Be, Bi, Cd, Co, Cr, Cu, Fe, Hg, Mg, Mn, Mo, Ni, Pb, Sb, Sc, Se, Sm, Sn, Sr, Tl, V, and Zn) were determined in skin-contact clothes. Analysed clothes were made of different materials, colours, and brands. Interestingly, we found high levels of Cr in polyamide dark clothes (605 mg/kg), high Sb concentrations in polyester clothes (141 mg/kg), and great Cu levels in some green cotton fabrics (around 280 mg/kg). Dermal contact exposure and human health risks for adult males, adult females, and for <1-year-old children were assessed. Non-carcinogenic and carcinogenic risks were below safe (HQ<1) and acceptable (<10{sup −6}) limits, respectively, according to international standards. However, for Sb, non-carcinogenic risk was above 10% of the safety limit (HQ>0.1) for dermal contact with clothes. - Highlights: • We determined in skin-contact clothes the concentrations of a number of metals. • Dermal contact exposure and health risks for adults and for 1-year-old children were assessed. • Carcinogenic risks were considered as acceptable (<10{sup −6}). • For non-carcinogenic risks, only Sb exceeded a 10% of the HQ for dermal contact with clothes.

  1. Mayas de Yucatán, México

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    Judith Ortega Canto

    2006-01-01

    Full Text Available El artículo describe y analiza el proceso de transformación de las representaciones sociales respecto a la salud/enfermedad/atención de procesos de embarazo-partopuerperio, a través de tres generaciones de parejas y la condición de género. Es a partir del papel que juega la ideología biomédica representada en las clínicas de campo de la seguridad social, y las relaciones que operan entre hombres y mujeres, que es posible distinguir los elementos protectivos y curativos, así como los elementos de tensión existentes. El trabajo muestra cómo juegan los géneros a través de tres generaciones en términos de colaboración mutua, su demanda y evaluación a la atención recibida por las parteras o a los servicios de atención alópatas, y el efecto de la medicalización sobre hombres y mujeres de la tercera generación.

  2. Caracterização microbiológica e clínica de surtos de "red leg" em Minas Gerais e avaliação do efeito bactericida in vitro do Vantocil IB® para Aeromonas hydrophila Microbiological and clinical characterization of "red leg" outbreaks in Minas Gerais, Brazil, and evaluation of in vitro bacterial effects of Vantocil IB® for Aeromonas hydrophila

    Directory of Open Access Journals (Sweden)

    Anna Christina de Almeida

    2000-08-01

    Full Text Available Com o objetivo da caracterização da ocorrência de "red leg" em Minas Gerais, avaliaram-se rãs jovens e adultas que apresentavam úlceras nas patas e dedos, derrame hemorrágico na pele da região ventral, incoordenação motora, altas taxas de mortalidade em adultos e abscessos hepáticos à necropsia. No cultivo de fragmentos de pele lesada e abscessos, foi isolado e identificado Aeromonas hydrophila. O efeito bactericida do VANTOCIL IB® foi superior ao permanganato de potássio, determinado pela concentração inibitória mínima para colónias isoladas.With the objective of characterizating lhe ocurrence of "red leg" in Minas Gerais, Brazill, young and adult frogs which presented in theirpads and limbs hemorragie in the skin of the ventral region, incordination, high death rate in adults and hepatic abscess at necropsy, have been evaluated. In fragment culture ofdamage skin and abscess, Aeromonas. hydrophila hás been isolated and identified. The bactericidal effect of VANTOCIL IB® was higher than that of potassium permanganate, as determinated by the minimal inhibitory concentration for isolated colonies.

  3. Primer registro de Elachistocleis skotogaster Lavilla, Vaira & Ferrari, 2003 (Anura: Microhylidae para la provincia de Formosa, Argentina

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    Kehr, Arturo Ignacio

    2011-10-01

    Full Text Available Entre el 4 de marzo y el 25 de abril de 2011, en 6 sistemas de trampas instalados en la Provinciade Formosa, Ciudad de Las Lomitas, Departamento Patiño, Ruta Nacional N° 81, Establecimiento Sumayen 2000 (24°39'49,4" S; 60°38'29,9" O; 137 m.s.n.m.; datum WGS84, fueron colectados 32 microhílidos con vientre gris manchado de blanco, y características franjas y manchas de color naranja endiferentes partes de las patas, axilas e ingle. Dichos ejemplares, correspondientes al género Elachistocleis se encuentran depositados en la colección herpetológica del Laboratorio de Herpetología del Centro de Ecología Aplicada del Litoral. Luego de analizar los ejemplares colectados (fijados y preservados en formol al 10% consideramos que se trata de E. skotogaster por presentarlas siguientes características morfológicas externas especificadas por Lavilla et al. (2003.

  4. A new genus and species of the family Lethaxonidae (Acari, Parasitengona, Hydrachnidia from the island of Coiba (Panama

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    Valdecasas, A. G.

    2010-06-01

    Full Text Available Transitia carlosi n. gen. n. sp. of the family Lethaxonidae is described from the interstitial environment of a small stream in Central America. Following a morphological revision of the adult variation in the family, Transitia n. gen. is proposed, characterized by a posteriorly tapering body shape, three pairs of acetabula arranged linearly, median position of male gonopore in relation to first pair of genital acetabula and slight sexual dimorphism of male legs.

    Se describe Transitia carlosi n. gen. n. sp. de la familia Lethaxonidae del medio intersticial de un pequeño río en America Central. Tras la revisión morfológica de la variación en los adultos de la familia se propone Transitia n. gen., caracterizado por una forma del cuerpo estrechada posteriormente, tres pares de acetábulas dispuestos linealmente, posición media del gonóporo del macho en relación a los acetábulas genitales y ligero dimorfismo sexual de las patas del macho.

  5. Universidad, ciudadanía y TIC

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    José Ignacio Iñaki Chaves

    2014-01-01

    Full Text Available ¿Está el mundo del siglo XXI del revés? Si miramos las noticias que nos venden los medios masivos de difusión de noticias y si analizamos la realidad social que nos rodea, la respuesta es SÍ. Si el mundo está patas arriba significa que la escuela, que forma parte de ese mundo, también se encuentra así. Dice Eduardo Galeano que si “(… el plomo aprende a flotar y el corcho, a hundirse. Las víboras aprenden a volar y las nubes aprenden a arrastrarse por los caminos” es que el mundo definitivamente está al revés. ¿Por qué este planteamiento inicial para hablar de Universidad, de ciudadanía y de nuevas tecnologías? Porque considero que en la situación del mundo de hoy, digital y pro-tecnológico en lo comunicativo, depredador y ciego en lo medioambiental, neoliberal y dictatorial en lo político, y capitalista y explotador en lo económico, tienen un rol relevante los tres campos enunciados en el título del presente artículo.

  6. APLICACIÓN DEL MÉTODO TERRITORII EN DOS ASENTAMIENTOS ESPONTÁNEOS DE PUERTO MADRYN, ARGENTINA

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    María Paula Ferrari

    2016-01-01

    Full Text Available El objetivo del trabajo es realizar un diagnóstico socio-territorial de dos asentamientos espontáneos de la ciudad de Puerto Madryn (Chubut, Argentina: La Lomita y Alta Tensión, a partir de la aplicación del Método Territorii y sus ocho fases -territorios reales, vividos, pasados, legales, pensados, posibles, concertados e inteligentes. El propósito es acompañar a las comunidades en la construcción de territorios más sustentables e identificar en los actores partícipes del proceso en qué medida están presentes las cuatro modalidades de transformación propuestas por la Red Internacional de Inteligencia Territorial: subjetiva, social, ambiental y desicional, así como también las “cuatro patas de la mesa” de la inteligencia territorial latinoamericana: actores públicos, comunitarios, empresarios y científicos.

  7. Ecocardiografía fetal: Evaluación y resultados de un Programa Nacional. Cuba 1989-1991

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    Andrés Savío Benavides

    1995-04-01

    Full Text Available Se exponen los resultados del Programa Nacional para el Diagnóstico Prenatal de las Cardiopatías por Ultrasonido, cuyo objetivo es contribuir a la reducción de la mortalidad infantil. Dicho programa se basa en el esquisaje masivo a las 20 semanas, de la imagen de las 4 cavidades del corazón fetal, la que es relativamente fácil de obtener en el examen ultrasonográfico rutinario que se practica en Cuba a todas las embarazadas. De 1 424 pacientes examinados entre 1989 y 1991 se diagnosticaron 94 cardiopatías (7 % de positivos. Las cardiopatías más frecuentes fueron: síndrome de hipoplasia de cavidades izquierdas (20,2 %, defecto de septación atrioventricular (15,9 % y la atresia tricuspídea (10,6 %. El 81,9 % de las embarazadas optó por la interrupción del embarazo. El resto decidió continuarlo, por lo cual se le brindó atención inmediata y óptica al recién nacido cardiópata, lo que contribuyó a la disminución de la mortalidad infantil por cardiopatías congénitas.

  8. On the Origin of Post-Aspirated Stops: Production and Perception of /s/ + Voiceless Stop Sequences in Andalusian Spanish

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    Hanna Ruch

    2016-03-01

    Full Text Available The present study investigates the role of articulatory and perceptual factors in the change from pre- to post-aspiration in two varieties of Andalusian Spanish. In an acoustic study, the influence of stop type, speaker age, and variety on the production of pre- and post-aspiration was analyzed in isolated words produced by 24 speakers of a Western and 24 of an Eastern variety, both divided into two age groups. The results confirmed previous findings of a sound change from pre- to post-aspiration in both varieties. Velar stops showed the longest, bilabials the shortest, and dental stops intermediate pre- and post-aspiration durations. The observed universal VOT-pattern was not found for younger Western Andalusian speakers who showed a particularly long VOT in /st/-sequences. A perception experiment with the same subjects as listeners showed that post-aspiration was used as a cue for distinguishing the minimal pair /pata/-/pasta/ by almost all listeners. Production-perception comparisons suggested a relationship between production and perception: subjects who produced long post-aspiration were also more sensitive to this cue. In sum, the results suggest that the sound change has first been actuated in the dental context, possibly due to a higher perceptual prominence of post-aspiration in this context, and that post-aspirated stops in Andalusian Spanish are on their way to being phonologized.

  9. Avaliação da atividade antiinflamatória e analgésica do extrato bruto hidroalcoólico do zoantídeo Palythoa caribaeorum (Duchassaing & Michelotti, 1860 Evaluation of the anti-inflammatory and analgesic activity of the crude hydroalcoholic extract of the zoanthid Palythoa caribaeorum (Duchassaing & Michelotti, 1860

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    Carolina L.S. Soares

    2006-12-01

    Full Text Available O presente trabalho representa a primeira análise das atividades analgésica e antiinflamatória do extrato bruto hidroalcoólico do zoantídeo Palythoa caribaeorum. Foram realizados os testes de Writhing induzido por ácido acético (1%, 10 mL.kg-1 i.p. e da chapa quente em camundongos para avaliar o efeito analgésico; e o teste de edema de pata de rata induzido por carragenina para avaliar a atividade antiinflamatória. As análises evidenciaram atividade analgésica no teste de Writhing no grupo tratado com 200 mg.kg-1 v.o. de extrato, com uma inibição de 47,22% do número de contorções abdominais ("Writhings", revelando atividade estatisticamente significativa.This work represents the first pharmacological analysis on the crude hydroalcoholic extract of Palythoa caribaeorum. The analgesic activity was assayed in acetic acid-induced writhing test and with the hot-plate test with mice; while the anti-inflammatory activity was evaluated in carrageenan-induced hind paw edema in the rat. The analysis suggested an analgesic activity in the Writhing test on the group treated with the crude extract (200 mg.kg-1 v.o. with an abdominal contortion’s inhibition of 47,22 %.

  10. Pensamientos de un violador en serie

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    Javier Urrá

    2006-01-01

    Full Text Available El presente artículo corresponde a un estudio de caso, en el que el autor describe material obtenido de trabajar directamente con V.S.R., con el fin de ilustrar los pensamientos de un violador en serie y, a la vez, esclarecer algunos elementos teóricos del psicópata. El documento describe a V.S.R. como un condenado a pena de prisión de 20 años por tres violaciones consumadas, al cumplir 23 años y estando en un centro de reforma, puede reingresar a prisión o bien quedar en la calle con una medida de libertad vigilada. Se solicita informe del Psicólogo Forense adscrito a la Fiscalía para su evaluación y orientación de la medida. A través de las entrevistas y análisis del expediente llegaremos a conocer los verdaderos pensamientos y patología de un agresor sexual reiterativo.

  11. A new species of Caenis (Ephemeroptera: Caenidae from Colombia Una nueva especie de Caenis (Ephemeroptera: Caenidae de Colombia

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    Carlos Molineri

    2009-12-01

    Full Text Available The new species Caenis tarapoto is described from male imagos collected in the Amazonas region from Colombia. This new species is characterized by a dark brown general coloration, presternal triangle anteriorly pointed, forelegs 0.7-0.9 times length of body, forceps apically pointed, central sclerite of styliger plate elongated, penes with gently convex posterior margin and with lobes of penes completely fused and projected laterally.La nueva especie Caenis tarapoto es descripta a partir de imagos machos colectados en la región Amazónica de Colombia. Esta nueva especie se caracteriza por una coloración general castaña oscura, triángulo prosternal aguzado anteriormente, patas anteriores 0.7-0.9 veces la longitud del cuerpo, forceps aguzados en el ápice, esclerito central de la placa estilígera elongado, penes con margen posterior suavemente convexo y con lóbulos peneanos completamente fusionados y proyectados lateralmente.

  12. Interacciones de pesquerías ribereñas en Bahía Magdalena-Almejas, Baja California Sur

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    Miguel A. Ojeda Ruiz de la Peña

    2012-01-01

    Full Text Available Con el fin de aportar al desarrollo de un modelo conceptual sobre la pesca ribereña o artesanal en el área de Bahía Magdalena-Almejas, Baja California Sur, se jerarquizó la importancia de 14 pesquerías de la región. La calificación se basó en un análisis cualitativo por puntos y en la estimación de un índice de importancia relativa, con indicadores como los promedios de captura, valor y frecuencia de registro de especies objetivo en desembarcos de embarcaciones menores, de 1998 a 2009; entre ellas están: almeja catarina, escama, camarón, callo de hacha, tiburón, jaiba, calamar, almeja pata de mula, rayas, lisa, pulpo, abulón, langosta y caracol chino. La interacción temporal entre varias de ellas es controlada por vedas oficiales, pero cuando ocurre se reconocen posibles efectos por pesca incidental e ilegal y modificaciones al ecosistema.

  13. Solid-State Disk with Double Data Rate DRAM Interface for High-Performance PCs

    Science.gov (United States)

    Kim, Dong; Bang, Kwanhu; Ha, Seung-Hwan; Park, Chanik; Chung, Sung Woo; Chung, Eui-Young

    We propose a Solid-State Disk (SSD) with a Double Data Rate (DDR) DRAM interface for high-performance PCs. Traditional SSDs simply inherit the interface protocol of Hard Disk Drives (HDD) such as Parallel Advanced Technology Attachment (PATA) or Serial-ATA (SATA) for maintaining the compatibility. However, SSD itself provides much higher performance than HDD, hence the interface also needs to be enhanced. Unlike the traditional SSDs, the proposed SSD with DDR DRAM interface is placed in the North Bridge which provides two or more DDR DRAM interface ports in high-performance PCs. The novelty of our work is on DQS signaling scheme which allows arbitrary Column Address Strobe (CAS) latency unlike typical DDR DRAM interface scheme. The experimental results show that the proposed SSD maximally outperforms the traditional SSD by 8.7 times in read mode, by 1.5 times in write mode. Also, for synthetic workloads, the proposed scheme shows performance improvement over the conventional architecture by a factor of 1.6 times.

  14. Prevención de factores de riesgo: Impacto del ejercicio y los programas de rehabilitación cardiovascular en el riesgo cardiovascular de pacientes coronarios

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    Dr. Arnaldo Angelino

    2012-11-01

    Full Text Available Los Factores de Riesgo Cardiovascular (FRC son la base para la aparición de enfermedades cardiovasculares, establecen una fuente de discapacidad social, laboral y familiar y contribuyen al incremento de la mortalidad general. Para tratarlos contamos con fármacos y medidas higiénicas dietéticas, entre las que destacamos al ejercicio. El concepto de rehabilitación cardiovascular multitrat es importante tanto desde lo médico (equipo multidisciplinario como desde el paciente (paciente y familia. Prescribir ejercicio a personas que durante la mayor parte de su vida han sido sedentarias, modificar hábitos y costumbres es difícil. La prescripción es individual, requiere de una evaluación y se adecuará a las posibilidades de ejecución, debe tener un inicio prudente, aumentar progresivamente su intensidad y planificarse por un largo período con sesiones similar a un cardiópata en rehabilitación cardiovascular. El ejercicio es una herramienta central pero el concepto multitrat involucra una novedosa cantidad de elementos imprescindibles para pretender un éxito significativo en el tratamiento de la enfermedad cardiovascular.

  15. Avaliação do cetoconazol em camundongos inoculados com Paracoccidioides brasiliensis pela histopatologia de fígado e baço e pela intradermorreação de paracoccidioidina

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    Maria do Rosário Rodrigues Silva

    1994-03-01

    Full Text Available Camundongos machos albinos, foram inoculados por via intravenosa com 0,5xl07 células leveduriform.es viáveis de Paracoccidioides brasiliensis da amostra rotulada como Pb 2052 e tratados diariamente com cetoconazol nas dosagens de 50 e 100mg/kg durante 50 dias e em seguida sacrificados. Observou-se o número de parasitas .formação de granulomas no fígado e baço e reação de hipersensibilidade retardada usando-se antígeno de P. brasiliensís preparada segundo Fava Neto, inoculado na pata direita do animal. Verificou-se que: 1. cetoconazol diminuiu acentuadamente o número de parasitas encontrados no fígado e baço; 2. não havia diferença entre o número de granulomas formados no baço e fígado de animais tratados e não tratados; 3. a intensidade dos testes cutâneos tardios foram similares em todos os animais.

  16. Efecto de la edad, el sexo y el tiempo en la biometría del Piquituerto común (Loxia curvirostra curvirostra en Navarra = Effect of age, sex and time in the biometrics of common crossbill (Loxia curvirostra curvirostra in Navarre.

    Directory of Open Access Journals (Sweden)

    D. Alonso, J. Arizaga

    2005-01-01

    Full Text Available Se estudia en detalle la biometría del Piquituerto Común (Loxia curvirostra curvirostra en Navarra (N de España, W de Pirineos, según los sexos, edad y el año de captura. entre 1994 y 2006 se capturaron un total de 2101 aves, en dos localidades emplazadas en bosques de pino silvestre (Pinus sylvestris. Además de la edad y sexo, en cada ejemplar se tomaron diez medidas, relacionadas con el ala, cola, pata y pico, y la morfología del ala de 2004 a 2006. Para toda variable hubo diferencias significativas entre los sexos y edades, presentando los valores máximos los machos adultos, y los mínimos las hembras jóvenes. Tras eliminar el efecto de la edad y sexo, se observaron diferencias interanuales, posiblemente debido a la ocurrencia de aves irruptivas. en lo relativo a la morfología alar, la especie parece mostrar en promedio alas apuntadas y cóncavas, sugiriendo cierta naturaleza nómada, tal vez debido a la variabilidad en la producción de semillas en el pino silvestre. Además, se registraron diferencias entre los sexos, mostrando los machos un ala más apuntada y convexa. Se desconocen por ahora las causas de esta variabilidad.

  17. Autoconsumo de hierbas medicinales en usuarios con enfermedades cardio-vasculares en una comuna de Chile

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    Lizet Veliz-Rojas

    2015-09-01

    Full Text Available Objetivo: Caracterizar el autoconsumo de hierbas medicinales en usuarios con enfermedades cardiovasculares. Metodología: Estudio de tipo cuantitativo y transversal, con una muestra de 257 personas. Los instrumentos recolectores de datos fueron un cuestionario y la revisión de la ficha clínica. Se utilizó un análisis descriptivo univariante apoyado en SPSS. Resultados: El 80,80% de los encuestados usó hierbas medicinales, y el 72,76% señaló no informar esta práctica al equipo de salud. Las hierbas medicinales más utilizadas para el control de la enfermedad cardiovascular fueron: el limón (20,6% para bajar la presión arterial, la pata de vaca (7% para reducir la glicemia y la alcachofa (3,5% para controlar el colesterol. Conclusiones: La mayoría de los participantes recurrieron a las hierbas medicinales, pese a ser una práctica de autocuidado prevalente, no es informada al equipo de salud. Algunas hierbas utilizadas por la muestra para controlar la enfermedad cardiovascular, están descritas sus usos para otras causas. Esta situación podría reflejar el desconocimiento sobre su utilización. Se sugiere el desarrollo de estrategias para el adecuado uso de las hierbas medicinales en atención primaria, enfocado en la integralidad en salud.

  18. Demodicose suína no norte do estado do Rio de Janeiro: relato de caso

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    R.L Silveira

    2012-06-01

    Full Text Available Um leitão oriundo de um criatório do norte do estado do Rio de Janeiro, mantido no biotério do Hospital Veterinário da Universidade Estadual do Norte Fluminense Darcy Ribeiro e utilizado como caso piloto de projeto de pesquisa para investigações sobre o acesso videolaparoscópico retal (NOTES - Natural Orifice Translumenal Endoscopic Surgery, foi eutanasiado e necropsiado. Amostras do ponto de acesso do tubo de inserção na região mucocutânea anal foram colhidas, fixadas em formalina neutra tamponada a 10%, processadas por inclusão em parafina e coradas pela hematoxilina e eosina para histologia. Observou-se o comprometimento de folículos que, dilatados, exibiam formações que lembravam Demodex spp. cortados em vários sentidos e, por se tratar de ácaros espécie-específicos, concluiu-se como D. phylloides. Na citopatologia, o ácaro foi recuperado e identificado a fresco, mostrando-se alongado, com quatro pares de patas ventrais e no terço anterior do corpo. Este se refere ao primeiro registro de demodicose suína no estado do Rio de Janeiro.

  19. Atividade antiinflamatória do granulado de Calendula officinalis L. e Matricaria recutita L.

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    L.R. Sartori

    2003-01-01

    Full Text Available Este trabalho descreve os resultados da atividade antiinflamatória de um granulado composto pelos extratos secos de Calendula officinalis L. e Matricaria recutita L. (GECOMR® - granulado encapsulado de Calendula officinalis e Matricaria recutita. Estas espécies são utilizadas na medicina popular devido às suas atividades antiinflamatória, antiúlcera gástrica e antiespasmódica. A redução do processo edematogênico nos grupos de animais tratados com o GECOMR foi observada para todos agentes inflamatórios testados (Carragenina, dextrana e histamina. Esta associação mostrou-se eficaz sobre os modelos de edema de pata induzidos pelas diferentes substâncias inflamatórias, com as doses de 100 e 250 mg.kg-1. A associação dos extratos hidroalcoólicos destas espécies medicinais não modificou a indicação isolada de cada uma.

  20. A atitude do cão na micção e os hormônios sexuais The body posture of the dog during micturition, and sex hormones

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    Thales Martins

    1946-06-01

    Full Text Available Neste trabalho foi estudada a influência dos hormônios sexuais sôbre a atitude do cão no ato de urinar. Enquanto nos machos castrados depois de quarto mês de idade não é evitado o aparecimento da atitude característica de elevação de uma das patas traseiras durante a emissão da urina, os castrados antes de segundo mês, em regra, conversam na idade adultao tipo infantil, isto é, afastamento das patas posteriores e leve abaixamento da bacia. A castração precoce, entretanto, não impede as tentativas copulatórias como a monta e os movimentos pélvicos. Cães castrados na infância e mantendo na idade afulta o comportamento infantil de micção começam a elevar uma das patas trazeiras depois do tratamento pela testosterona. O tratamento de machos castrados com estrogênicos não provocou o aparecimento da atitude urinária feminina, que é caracterizada pela flexão das patas traseiras, e abaixamento muito acentuado do trem posterior. Também a administração de testosterona a cadelas normais ou castradas, em regra, não fez, com que elas exibissem a postura masculina, esboçada apenas num único caso. A importância dos fatôres hormonais e nervosos envolvidos no mecanismo regulador foi comentada e discutida. Do exposto, pode-se concluir que o dimorfismo postural do cão no ato de urinar é um caráter sexual secundário e, pelo menos no macho, dependente da testosterona.It is known that dogs and bitches exhibit a peculiar body posture during micturition. In the infantile male, the hind limbs are spread with slight drooping of the pelvis; in the adult one of the hind legs is lifted, with flexion and adduction of the limb, urine being emmitted, in most cases, against a vertical object. This adult pattern has been initiated in our dogs between 5 and 8 months of age. In the infantile or adult female there is a flexion of both hind limbs, with pronounced drooping of the pelvis. Castration and hormonal treatment of males - Castration