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Sample records for 01llb k58 h21

  1. Preparation of a Lipopolysaccharide from Escherichia coli 01lla, 01llb, k58: h21 bacterial wall, labeled with carbon-14; Preparacion de un lipopolisacarido de la pared baceteriana de escherichia coli 01lla, 01llb, K58: H21, marcado con carbono-14

    Energy Technology Data Exchange (ETDEWEB)

    Solano Aunon, M. L.; Pacheco Lopez, J.; Garcia Pineda, M. D.; Roca, M.; Bayon, A.

    1981-07-01

    A brief description of the morphological and chemical structure of Li po polysaccharides is given, as well as its occurrence in nature and its mechanisms of action. It is emphasized the usefulness for actual biochemical and biomedical research of the labeled Lipopolysaccharide. The method for the labelling, isolation and purification of 14''C-Lipopolysacchari de is described. (Author) 23 refs.

  2. Avia pursuit airplane B.H. 21

    Science.gov (United States)

    Serryer, J

    1926-01-01

    Built by the 'Czecho-Slovakian' aircraft factory, AVIA, the B.H. 21, has a top speed of 250 MPH, and carries 120 kg of gasoline and 20 kg of oil, giving it a radius of action of 600-650 km. It is equipped with a Hispano-Suiza engine capable of 300 HP.

  3. Glycosaminoglycans enhance the fibrillation propensity of the ß2-microglobulin cleavage variant--¿K58-ß2m

    DEFF Research Database (Denmark)

    Corlin, Dorthe B; Johnsen, Christina K; Nissen, Mogens H;

    2010-01-01

    Dialysis related amyloidosis (DRA) is a serious complication to long-term hemodialysis treatment which causes clinical symptoms such as carpal tunnel syndrome and destructive arthropathies. The disease is characterized by the assembly and deposition of ß2-microglobulin (ß2m) predominantly....... In this study, we show that fibrillogenesis of a cleavage variant of ß2m, ¿K58-ß2m, which can be found in the circulation of hemodialysis patients and is able to fibrillate at near-physiological pH in vitro, is affected by the presence of copper ions and heparan sulfate. It is found that the fibrils generated...... when heparan sulfate is present have increased length and diameter, and possess enhanced stability and seeding properties. However, when copper ions are present the fibrils are short, thin and less stable, and form at a slower rate. We suggest that heparan sulfate stabilizes the cleaved monomers...

  4. Observation of a 331 K (58 degrees C) spin transition for bis[hydrotris (1,2,4-triazol-1-yl)borate]iron(II) by variable temperature infrared spectroscopy and magnetic susceptibility measurements

    NARCIS (Netherlands)

    van Koningsbruggen, Petra J.; Miller, Joel S.

    2008-01-01

    Fe{HB(C(2)H(2)N(3))(3)}(2) is observed by variable temperature infrared and magnetic studies to have a spin transition between the low spin S = 0 and high spin S = 2 states at 331 K (58 degrees C) with thermal hysteresis of similar to 1.5 K. Changes in the triazole ligand IR absorptions demonstrate

  5. Fluorescence Quenching of Anthracene by N,N-Diethylaniline and Phenothiazine in Triton X-100/n-C10H21OH/H2O Microemulsion

    Institute of Scientific and Technical Information of China (English)

    GUO Xia; XU Hui; GUO Rong

    2003-01-01

    The photo-induced electron transfer reactions of anthracene with N,N-diethylaniline(DEA) and phenothiazine(PTZ) occur in the membrane phase of a Triton X-100/n-C10H21OH(1-decanol)/H2O microemulsion. DEA and PTZ exist in the membrane phase of the microemulsion. Anthracene exists in the oil continuous phase of the W/O microemulsion and in the oil core and membrane phase of the O/W microemulsion.

  6. Characterization of a chromosomally integrated luxCDABE marker for investigation of shiga toxin-producing Escherichia coli O91:H21 shedding in cattle

    Science.gov (United States)

    Hong, Yingying; Mathew, Alan G.

    2011-06-01

    Shiga toxin-producing Escherichia coli (STEC) O91:H21 has been recognized as a potential life-threatening foodborne pathogen and is commonly involved in human infections in European countries. Fecal shedding of the organism by cattle is considered to be the ultimate source for contaminations. Studies examining STEC shedding patterns often include inoculation of strains carrying antibiotic resistance makers for identifiable recovery. However, indigenous intestinal microflora exhibiting similar antibiotic resistance patterns can confound such studies. Such was the case in a study by our group when attempting to characterize shedding patterns of O91:H21 in calves. A chromosomally integrated bioluminescence marker using a luxCDABE cassette from Photorhabdus luminescens was developed in O91:H21 to overcome such shortcomings of antibiotic resistance markers during animal challenge experiment. The marker was validated in various aspects and was shown to have no impact on metabolic reactions, isotype virulence gene patterns, cost to growth, and additionally demonstrated high in vitro stability. Together, the results indicated that a chromosomally integrated luxCDABE based marker may be a superior system for the study of STEC colonization and shedding in cattle.

  7. A new alpha-globin variant with increased oxygen affinity in a Swiss family: Hb Frauenfeld [alpha 138(H21)Ser-->Phe, TCC>TTC (alpha 2)].

    Science.gov (United States)

    Hochuli, Michel; Zurbriggen, Karin; Schmid, Marlis; Speer, Oliver; Rochat, Philippe; Frauchiger, Beat; Kleinert, Peter; Schmugge, Markus; Troxler, Heinz

    2009-01-01

    A new alpha-globin mutation [alpha 138(H21)Ser-->Phe] was found in a 55-year-old male proband with an erythrocytosis known since his youth. Cation exchange high performance liquid chromatography (HPLC) revealed an additional peak eluting slightly before Hb A indicating the presence of a variant. The peak area of the variant was approximately one-third that of Hb A suggesting an alpha-globin variant. Matrix-assisted laser desorption ionization-time-of-flight mass spectrometry analysis confirmed the mutation at the protein level. The variant is also detectable with isoelectric focusing and reversed phase HPLC. DNA analysis revealed a heterozygous sequence mutation at codon 138 of the alpha2 gene. A C>T transition at the second nucleotide of the codon indicated a Ser-->Phe exchange. The variant showed increased oxygen affinity and was named Hb Frauenfeld.

  8. C15H21RuSe

    Science.gov (United States)

    Mikhova, B. M.

    This document is part of Subvolume D5 `Chemical Shifts and Coupling Constants for Carbon-13. Part 5: Organometallic Compounds' of Volume 35 `Nuclear Magnetic Resonance Data' of Landolt-Börnstein Group III: `Condensed Matter'.

  9. The Regulation of Expression of the Stx2d Toxins in Shiga Toxin-producing Escherichia coli O91:H21 Strain B2F1

    Science.gov (United States)

    2002-01-01

    EHEC 1 group consists only of O157:H7 and O157:NM, two serotypes that appear to represent recent clones that have spread globally . Members of the...which carnitine is used in the bacterial cell (Fig. 22). The role this gene might have as a global regulator is unclear; however, the caiD-coding...mRNA secondary structure in differential expression of Shiga toxin genes J.Bacteriol. 175: 597-603. Hamilton,C.M., Aldea ,M., Washburn,B.K

  10. SPECIAL SESSION: (H21) on Global Precipitation Mission for Hydrology and Hydrometeorology. Sampling-Error Considerations for GPM-Era Rainfall Products

    Science.gov (United States)

    Bell, Thomas L.; Lau, William K. M. (Technical Monitor)

    2002-01-01

    The proposed Global Precipitation Mission (GPM) builds on the success of the Tropical Rainfall Measuring Mission (TRMM), offering a constellation of microwave-sensor-equipped smaller satellites in addition to a larger, multiply-instrumented "mother" satellite that will include an improved precipitation radar system to which the precipitation estimates of the smaller satellites can be tuned. Coverage by the satellites will be nearly global rather than being confined as TRMM was to lower latitudes. It is hoped that the satellite constellation can provide observations at most places on the earth at least once every three hours, though practical considerations may force some compromises. The GPM system offers the possibility of providing precipitation maps with much better time resolution than the monthly averages around which TRMM was planned, and therefore opens up new possibilities for hydrology and data assimilation into models. In this talk, methods that were developed for estimating sampling error in the rainfall averages that TRMM is providing will be used to estimate sampling error levels for GPM-era configurations. Possible impacts on GPM products of compromises in the sampling frequency will be discussed.

  11. Mutations in the Histone-like Nucleoid Structuring Regulatory Gene (hns) Decrease the Adherence of Shiga Toxin-producing Escherichia coli 091:H21 Strain B2F1 to Human Colonic Epithelial Cells and Increase the Production of Hemolysin

    Science.gov (United States)

    1999-10-19

    long wave ultra- violet light (Chapman et aI., 1991; Zadik et al., 1993). Because 0157:H7 strains are negative for p-glucuronidase this test...by cross-linking with ultra violet (UV) light (Church and Gilbert, 1984). The blot was blocked at least 4 hours before addition of labeled probe (see...with a trans-blot SO semi-dry apparatus (Bio-Rad). The membranes were blocked with 5% nonfat dried milk ( Carnation Co., Los Angeles, CAl in Tris

  12. Dicty_cDB: Contig-U03047-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ,37h,61h La... 46 4.2 1 ( EX346464 ) GQ03103.SP6_H21 GQ031 - Xylem Scrapings (Normaliz... 46 4.2 1 ( EX34611...2 ) GQ03103.SP6.1_H21 GQ031 - Xylem Scrapings (Normal... 46 4.2 1 ( EX345398 ) GQ03103.B7.1_H21 GQ031 - Xylem Scraping

  13. Transformational leadership sub-dimensions and their link to leaders' personality and performance

    NARCIS (Netherlands)

    Deinert, A.; Homan, A.C.; Boer, D.; Voelpel, S.C.; Gutermann, D.

    2015-01-01

    The multi-dimensionality of the transformational leadership construct has been under debate in the last decades. To shed more light on this issue, we conducted a meta-analysis (k = 58 studies), examining the transformational leadership sub-dimensions and their links to leader personality and perform

  14. Dicty_cDB: Contig-U15472-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available X359575 ) GQ03201.SP6_H18 GQ032 - Shoot tip (Normalized lib... 46 4.0 1 ( EX345037 ) GQ03102.SP6_H21 GQ031 - Xylem Scraping...s (Normaliz... 46 4.0 1 ( EX344692 ) GQ03102.SP6.1_H21 GQ031 - Xylem Scrapings (Normal... 46

  15. AcEST: DK960100 [AcEST

    Lifescience Database Archive (English)

    Full Text Available 1. 5' end sequence. DK960100 - Show DK960100 Clone id TST39A01NGRL0006_H21 Library TST39 Length 690 Definiti...on Adiantum capillus-veneris mRNA. clone: TST39A01NGRL0006_H21. 5' end sequence. Accession DK960100 Tissue t...tein database search programs, Nucleic Acids Res. 25:3389-3402. Query= DK960100|Adiantum capillus-veneris mR...ucleic Acids Res. 25:3389-3402. Query= DK960100|Adiantum capillus-veneris mRNA, clone: TST39A01NGRL0006_H21,

  16. AcEST: DK952954 [AcEST

    Lifescience Database Archive (English)

    Full Text Available TST38A01NGRL0015_H21 616 Adiantum capillus-veneris mRNA. clone: TST38A01NGRL0015_H21. 5' end sequence. DK95...2954 - Show DK952954 Clone id TST38A01NGRL0015_H21 Library TST38 Length 616 Definiti...on Adiantum capillus-veneris mRNA. clone: TST38A01NGRL0015_H21. 5' end sequence. Accession DK952954 Tissue t... of protein database search programs, Nucleic Acids Res. 25:3389-3402. Query= DK952954|Adiantum capillus-ven...2 G 544 G Sbjct: 565 G 565 Score = 79.7 bits (195), Expect = 1e-14 Identities = 5

  17. SwissProt search result: AK069229 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK069229 J023012H21 (Q9TV66) Potassium/sodium hyperpolarization-activated cyclic nu...cleotide-gated channel 4 (Hyperpolarization-activated cation channel 4) (HAC-4) HCN4_RABIT 9e-16 ...

  18. SwissProt search result: AK069229 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK069229 J023012H21 (O88705) Potassium/sodium hyperpolarization-activated cyclic nu...cleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3) HCN3_MOUSE 4e-16 ...

  19. Are Eyewall Replacement Cycles Governed Largely by Axisymmetric Balance Dynamics?

    Science.gov (United States)

    2015-01-01

    rings. Our analysis re- veals a significant weakness of the classical model and highlights the necessity of the boundary layer spinup mechanism (Smith...Sawyer– Eliassen balance inversion described in AM14. Figure 2a shows that, at hour 36, the largest tangential wind maxi - mum occurs in the new single...surpassing 30ms21 h21 and the maxi - mum negative tendency just reaching 250ms21 h21. When compared to theRAMSpredictions, these balanced tendencies represent

  20. Dicty_cDB: VSF780 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 0.17 1 BU572652 |BU572652.1 PA__Ea0001H21f Almond developing seed Prunus dulcis cDNA clone PA__Ea0001H21f, ...mic clone UUGC1M0399K06 R, DNA sequence. 48 0.17 1 BU573578 |BU573578.1 PA__Ea0004H03f Almond developing

  1. Characterization and Virulence Assessment of Two 091:821 Enterohemorrhagic Escherichia Coli Isolates

    Science.gov (United States)

    1993-04-30

    Law, S. B. Richardson, M. petrie, J. L. Brunton, and x. Karaali. 1987. Glycolipid binding of natural and recomninant Escherichi coli produced...HAll AIR FORCE MEDICAL CENTER Title of Dissertation: ·Characterization and Virulence Assessment of Two 091: H21 Enterohemorrhagic Escherichia coli ...the thesis manuscript entitled : of any copyrighted "Characterization and Virulence Assessment of Two 091:H21 Enterohemorrhagic Escherichia coli

  2. A novel chalcone derivative attenuates the diabetes-induced renal injury via inhibition of high glucose-mediated inflammatory response and macrophage infiltration

    Energy Technology Data Exchange (ETDEWEB)

    Fang, Qilu [Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang (China); Zhao, Leping [Department of Pharmacy, the Affiliated Yueqing Hospital, Wenzhou Medical University, Wenzhou, Zhejiang (China); Wang, Yi; Zhang, Yali [Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang (China); Li, Zhaoyu [Department of International High School, Shanghai Jiaotong University Nanyang Affiliated (Kunshan) School, Minhang District, Shanghai (China); Pan, Yong; Kanchana, Karvannan; Wang, Jingying; Tong, Chao [Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang (China); Li, Dan, E-mail: yqyyld@163.com [Department of Nephrology, the Affiliated Yueqing Hospital, Wenzhou Medical University, Wenzhou, Zhejiang (China); Liang, Guang, E-mail: wzmcliangguang@163.com [Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang (China)

    2015-01-15

    Inflammation plays a central role in the development and progression of diabetic nephropathy (DN). Researches on novel anti-inflammatory agents may offer new opportunities for the treatment of DN. We previously found a chalcone derivative L6H21 could inhibit LPS-induced cytokine release from macrophages. The aim of this study was to investigate whether L6H21 could ameliorate the high glucose-mediated inflammation in NRK-52E cells and attenuate the inflammation-mediated renal injury. According to the results, L6H21 showed a great inhibitory effect on the expression of pro-inflammatory cytokines, cell adhesion molecules, chemokines, and macrophage adhesion via down-regulation of NF-κB/MAPKs activity in high glucose-stimulated renal NRK-52E cells. Further, in vivo oral administration with L6H21 at a dosage of 20 mg/kg/2 days showed a decreased expression of pro-inflammatory cytokines, cell adhesion molecules, which subsequently contributed to the inhibition on renal macrophage infiltration, the reduction of serum creatinine and BUN levels, and the improvement on the fibrosis and pathological changes in the renal tissues of diabetic mice. These findings provided that chalcone derived L6H21 may be a promising anti-inflammatory agent and have the potential in the therapy of diabetic nephropathy, and importantly, MAPK/NF-κB signaling system may be a novel therapeutic target for human DN in the future. - Highlights: • Inflammation plays a central role in the development of diabetic nephropathy. • Compound L6H21 reduced the high glucose-mediated inflammation in NRK-52E cells. • Compound L6H21 attenuated the inflammation-mediated renal injury. • L6H21 exhibited anti-inflammatory effects via inactivation of NF-κB/MAPKs. • MAPKs/NF-κB may be a novel therapeutic target in diabetic nephropathy treatment.

  3. Survival in acidic and alcoholic medium of Shiga toxin-producing Escherichia coli O157:H7 and non-O157:H7 isolated in Argentina

    Directory of Open Access Journals (Sweden)

    Sanz Marcelo E

    2003-08-01

    Full Text Available Abstract Background In spite of Argentina having one of the highest frequencies of haemolytic uraemic syndrome (HUS, the incidence of Escherichia coli O157:H7 is low in comparison to rates registered in the US. Isolation of several non-O157 shiga toxin-producing Escherichia coli (STEC strains from cattle and foods suggests that E. coli O157:H7 is an uncommon serotype in Argentina. The present study was undertaken to compare the survival rates of selected non-O157 STEC strains under acidic and alcoholic stress conditions, using an E. coli O157:H7 strain as reference. Results Growth at 37°C of E. coli O26:H11, O88:H21, O91:H21, O111:H-, O113:H21, O116:H21, O117:H7, O157:H7, O171:H2 and OX3:H21, was found to occur at pH higher than 4.0. When the strains were challenged to acid tolerance at pH as low as 2.5, viability extended beyond 8 h, but none of the bacteria, except E. coli O91:H21, could survive longer than 24 h, the autochthonous E. coli O91:H21 being the more resistant serotype. No survival was found after 24 h in Luria Bertani broth supplemented with 12% ethanol, but all these serotypes were shown to be very resistant to 6% ethanol. E. coli O91:H21 showed the highest resistance among serotypes tested. Conclusions This information is relevant in food industry, which strongly relies on the acid or alcoholic conditions to inactivate pathogens. This study revealed that stress resistance of some STEC serotypes isolated in Argentina is higher than that for E. coli O157:H7.

  4. Amino Acid Substitutions That Affect Receptor Binding and Stability of the Hemagglutinin of Influenza A/H7N9 Virus

    Science.gov (United States)

    Schrauwen, Eefje J. A.; Burke, David F.; Rimmelzwaan, Guus F.; Herfst, Sander; Fouchier, Ron A. M.

    2016-01-01

    Receptor-binding preference and stability of hemagglutinin have been implicated as crucial determinants of airborne transmission of influenza viruses. Here, amino acid substitutions previously identified to affect these traits were tested in the context of an A/H7N9 virus. Some combinations of substitutions, most notably G219S and K58I, resulted in relatively high affinity for α2,6-linked sialic acid receptor and acid and temperature stability. Thus, the hemagglutinin of the A/H7N9 virus may adopt traits associated with airborne transmission. PMID:26792744

  5. Half-a-Century of the »Körmend Growth Study«

    OpenAIRE

    Eiben, O. G.; Tóth, G.

    2000-01-01

    The authors give a sketch about the „Körmend Growth Study« which is series of cross-sectional growth studies, carried out in Körmend, a small town in Western Hungary. The first investigation was carried out in 1958 (K-58) and it has been repeated every ten years (K-68, K-78, K-88, and K-98). All 3-18 year-old healthy boys and girls in nurseries and schools in Körmend were involved in the study. Twenty-three body measurements were taken. This paper focuses on changes in height, ...

  6. AcEST: DK950000 [AcEST

    Lifescience Database Archive (English)

    Full Text Available TST38A01NGRL0007_H21 704 Adiantum capillus-veneris mRNA. clone: TST38A01NGRL0007_H2...1. 5' end sequence. DK950000 CL57Contig1 Show DK950000 Clone id TST38A01NGRL0007_H21 Library TST38 Length 70...4 Definition Adiantum capillus-veneris mRNA. clone: TST38A01NGRL0007_H21. 5' end sequence. Accession DK95000...tabase search programs, Nucleic Acids Res. 25:3389-3402. Query= DK950000|Adiantum...T: a new generation of protein database search programs, Nucleic Acids Res. 25:3389-3402. Query= DK9500

  7. 早熟玉米新品种海玉14的选育及栽培技术

    Institute of Scientific and Technical Information of China (English)

    隋冬华; 唐贵; 唐克; 李瑞

    2012-01-01

    海玉14是海伦东升种业有限责任公司科研所2003年以自选系H20为母本,外引系H21为父本杂交选育而成。母本H20是合344与自330的二环系,父本H21是外引不稳定材料经多代连续自交选育而成的自交系。

  8. Recurrent Hemolytic and Uremic Syndrome Induced by Escherichia Coli

    Science.gov (United States)

    Commereuc, Morgane; Weill, Francois-Xavier; Loukiadis, Estelle; Gouali, Malika; Gleizal, Audrey; Kormann, Raphaël; Ridel, Christophe; Frémeaux-Bacchi, Véronique; Rondeau, Eric; Hertig, Alexandre

    2016-01-01

    Abstract A widespread belief is that typical hemolytic and uremic syndrome (HUS) does not recur. We report the case of a patient infected twice with raw milk taken from his own cow and containing a Shiga toxin–producing Escherichia coli O174:H21 that induced recurrent HUS causing severe renal and cerebral disorders. A genomic comparison of the human and bovine Shiga toxin–producing Escherichia coli O174:H21 isolates revealed that they were identical. Typical HUS may recur. Since milk from this animal was occasionally distributed locally, thereby posing a serious threat for the whole village, this particular cow was destroyed. PMID:26735524

  9. Influence of acid-soluble proteins from bivalve Siliqua radiata ligaments on calcium carbonate crystal growth

    Science.gov (United States)

    Huang, Zeng-Qiong; Zhang, Gang-Sheng

    2016-08-01

    In vitro biomimetic synthesis of calcium carbonate (CaCO3) in the presence of shell proteins is a heavily researched topic in biomineralization. However, little is known regarding the function of bivalve ligament proteins in the growth of CaCO3 crystals. In this study, using fibrous protein K58 from Siliqua radiata ligaments or coverslips as substrates, we report the results of our study of CaCO3 precipitation in the presence or absence of acid-soluble proteins (ASP) from inner ligament layers. ASP can disturb the controlling function of K58 or a coverslip on the crystalline phase, resulting in the formation of aragonite, calcite, and vaterite. In addition, we identified the following four primary components from ASP by mass spectroscopy: alkaline phosphatase (ALP), ABC transporter, keratin type II cytoskeletal 1 (KRT 1), and phosphate ABC transporter, phosphate-binding protein (PstS). Further analysis revealed that the first three proteins and especially ALP, which is important in bone mineralisation, could affect the polymorphism and morphology of CaCO3 crystals by trapping calcium ions in their domains. Our results indicate that ALP may play an important role in the formation of aragonite in S. radiata ligaments. This paper may facilitate our understanding of the biomineralization process.

  10. Unfolding, aggregation, and seeded amyloid formation of lysine-58-cleaved beta(2)-microglobulin

    DEFF Research Database (Denmark)

    Heegaard, N.H.H.; Jørgensen, T.J.D.; Rozlosnik, N.;

    2005-01-01

    beta(2)-Microglobulin (beta(2)m) is the amyloidogenic protein in dialysis-related amyloidosis, but the mechanisms underlying beta(2)m fibrillogenesis in vivo are largely unknown. We study a structural variant of beta(2)M that has been linked to cancer and inflammation and may be present in the ci......beta(2)-Microglobulin (beta(2)m) is the amyloidogenic protein in dialysis-related amyloidosis, but the mechanisms underlying beta(2)m fibrillogenesis in vivo are largely unknown. We study a structural variant of beta(2)M that has been linked to cancer and inflammation and may be present...... in the circulation of dialysis patients. This beta(2)M variant, Delta K58-beta(2)m, is a disulfide-linked two-chain molecule consisting of amino acid residues 1-57 and 59-99 of intact beta(2)m, and we here demonstrate and characterize its decreased conformational stability as compared to wild-type (wt) beta(2)M......, and at 37 degrees C the half-time for unfolding is more than 170-fold faster than at 15 degrees C. Conformational changes are also reflected by a very prominent Congo red binding of Delta K58-beta(2)m at 37 degrees C, by the evolution of thioflavin T fluorescence, and by changes in intrinsic fluorescence...

  11. (9E)-9-benzylidene-2-methylsulfanyl-5-phenyl-6,7,8,9-tetrahydropyrimido[4,5-b]quinolin-4(3H)-one: a hydrogen-bonded R2(2)(8) dimer.

    Science.gov (United States)

    Becerra, Diana; Insuasty, Braulio; Cobo, Justo; Glidewell, Christopher

    2013-12-15

    In the molecule of the title compound, C25H21N3OS, which was prepared by mild oxidation of the corresponding 5,6,7,8,9,10-hexahydro analogue, the fused carbocyclic ring adopts an envelope conformation. Pairs of molecules are linked into cyclic centrosymmetric dimers by pairs of inversion-related N-H···O hydrogen bonds.

  12. Dicty_cDB: FC-AR22 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available mRNA sequence. 50 0.023 1 BU572652 |BU572652.1 PA__Ea0001H21f Almond developing seed Prunus dulcis cDNA clo...BAC, RP23-158F1, complete sequence. 48 0.092 1 BU573578 |BU573578.1 PA__Ea0004H03f Almond developing

  13. Drug: D08757 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available Neurolite (TN) C12H21N2O5S2. Tc. 433.9956 436.3417 Therapeutic category: 4300 Therapeutic category of drugs... in Japan [BR:br08301] 4 Agents affecting cellular function 43 Radioactive drugs 430 Radioactive drugs 4300 Radioactive drugs

  14. Drug: D00080 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D00080 Drug Chondroitin sulfate A (JAN) (C14H21NO14S)n D00080.gif Same as: C00634 A...ntirheumatic agents, non-steroids M01AX25 Chondroitin sulfate D00080 Chondroitin sulfate A (JAN) CAS: 24967-

  15. Drug: D04752 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available onatremia [selective V2-receptor antagonist] arginine vasopressin receptor 2 (AVPR2...D04752 Drug Lixivaptan (USAN/INN) C27H21ClFN3O2 473.1306 473.9259 D04752.gif Treatment of nonhypovolemic hyp

  16. Drug: D00196 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D00196 Drug Physostigmine (USP); Eserine (TN) C15H21N3O2 275.1634 275.3461 D00196.g... D00196 Physostigmine (USP) CAS: 57-47-6 PubChem: 7847264 DrugBank: DB00981 LigandBox: D00196 NIKKAJI: J4.57

  17. Drug: D01288 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available 88 359.8466 D01288.gif Stimulant [respiratory] Same as: C12717 ATC code: R07AB08 Anatomical Therapeutic Chem...D01288 Drug Dimefline hydrochloride (JAN/USAN); Remeflin (TN) C20H21NO3. HCl 359.12

  18. Drug: D01804 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D01804 Drug Cadralazine (JP16/INN); Cadral (TN) C12H21N5O3 283.1644 283.3268 D01804...tives C02DB04 Cadralazine D01804 Cadralazine (JP16/INN) CAS: 64241-34-5 PubChem: 7848866 LigandBox: D01804

  19. Drug: D06633 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available 33.gif Insomnia, major depression, and schizophrenia 5-HT2A-receptor antagonist [HSA:3356] [KO:K04157] hsa04...D06633 Drug Pruvanserin hydrochloride (USAN) C22H21FN4O. HCl 412.1466 412.8877 D066

  20. 2,5,11,14-Tetraoxa-8-azadispiro[13.4.0]nonadeca-15,17,19-triene

    Directory of Open Access Journals (Sweden)

    Quanying Gan

    2010-05-01

    Full Text Available The title compound, C14H21NO4, has been synthesized from o-dihydroxybenzene by a three-step reaction. There are two chemically equal but crystallographically independent molecules in the asymmetric unit. The crystal packing is governed by C—H...O hydrogen bonds and C—H...π interactions, forming an infinite network.

  1. Drug: D07307 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D07307 Drug Cyamemazine (INN); Tercian (TN) C19H21N3S 323.1456 323.4551 D07307.gif Neuroleptic; Antihistamin...ic ATC code: N05AA06 Anatomical Therapeutic Chemical (ATC) classification [BR:br083

  2. Drug: D07756 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available 07756.gif Neuroleptic; Antihistaminic ATC code: N05AA06 Anatomical Therapeutic Chemical (ATC) classification...D07756 Drug Cyamemazine tartrate; Tercian (TN) C19H21N3S. C4H6O6 473.1621 473.542 D

  3. Drug: D02091 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available staminic ATC code: D04AA04 R06AC04 H1-receptor antagonist [HSA:3269] [KO:K04149] hs...D02091 Drug Tripelennamine hydrochloride (USP); PBZ-SR (TN) C16H21N3. HCl 291.1502 291.819 D02091.gif Antihi

  4. Drug: D06632 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available , major depression, and schizophrenia 5-HT2A-receptor antagonist [HSA:3356] [KO:K04157] hsa04020(3356) Calci...D06632 Drug Pruvanserin (USAN/INN) C22H21FN4O 376.1699 376.4267 D06632.gif Insomnia

  5. SwissProt search result: AK072740 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK072740 J023134H21 (Q9LEL5) 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransfer...ase (EC 2.1.1.116) (S-adenosyl-L-methionine:3'-hydroxy-N-methylcoclaurine 4'-O-methyltransferase) (4'-OMT) 4OMT_COPJA 3e-44 ...

  6. (E-N′-[4-(Dimethylaminobenzylidene]-2-(4-methylphenoxyacetohydrazide

    Directory of Open Access Journals (Sweden)

    M. K. Usha

    2014-02-01

    Full Text Available In the title compound, C18H21N3O2, the dihedral angle between the benzene rings is 68.85 (11°. In the crystal, the molecules are linked by C—H...O and N—H...O hydrogen bonds, as well as weak C—H...π contacts, forming a three-dimensional supramolecular architecture.

  7. Drug: D02968 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available 2968.gif Antiemetic in chemotherapy-induced emesis; Antidepressant; Treatment of psychiatric conditions [sub...D02968 Drug Aprepitant (JAN/USAN/INN); Emend (TN) C23H21F7N4O3 534.1502 534.4267 D0

  8. Drug: D09024 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D09024 Drug Totrombopag choline (USAN) C25H21N8O2. C5H14NO 569.2863 569.6574 D09024.gif Treatment of chemoth...erapy-induced thrombocytopenia, treatment of thrombocytopenia associated liver dise

  9. SwissProt search result: AK069229 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK069229 J023012H21 (P59111) Potassium voltage-gated channel subfamily H member 8 (...Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (Fragment) KCNH8_MOUSE 8e-17 ...

  10. EST Table: FY018488 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FY018488 rbmov22h21 11/11/04 97 %/265 aa ref|NP_001040121.1| endothelial-monocyte a...ctivating polypeptide II [Bombyx mori] gb|ABD36113.1| endothelial-monocyte activating polypeptide II [Bombyx

  11. EST Table: FY007658 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FY007658 bmov22h21 11/11/04 100 %/199 aa ref|NP_001040121.1| endothelial-monocyte a...ctivating polypeptide II [Bombyx mori] gb|ABD36113.1| endothelial-monocyte activating polypeptide II [Bombyx

  12. 2-[2-(2-Hydroxyethoxyphenyl]-4,4,5,5-tetramethyl-2-imidazoline-1-oxyl 3-oxide

    Directory of Open Access Journals (Sweden)

    Lin-Lin Jing

    2011-12-01

    Full Text Available In the title compound, C15H21N2O4, the nitronyl nitroxide unit displays a twisted conformation. The crystal structure is stabilized by non-classical C—H...O and C—H...π hydrogen bonds, which build up a three-dimensional network.

  13. Dichlorido(η6-toluene[tris(4-methoxyphenylphosphine]ruthenium(II

    Directory of Open Access Journals (Sweden)

    Rui-Xiang Li

    2008-02-01

    Full Text Available In the title compound, [RuCl2(C7H8(C21H21O3P], the RuII atom possesses a pseudo-octahedral geometry and the metrical parameters around the metallic core compare well with those of similar three-legged-piano-stool complexes.

  14. Drug: D07872 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D07872 Drug Dosulepin (INN); Dothiepin; Dothep (TN) C19H21NS 295.1395 295.4417 D07872.gif Antidepress...ant, trycyclic ATC code: N06AA16 Tricyclic antidepressants serotonin transporter inhibitor... [HSA:6532] [KO:K05037]; noradrenalin transporter inhibitor [HSA:6530] [KO:K05035] map07027 Antidepressants

  15. 27 CFR 21.49 - Formula No. 23-H.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Formula No. 23-H. 21.49 Section 21.49 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT... and Authorized Uses § 21.49 Formula No. 23-H. (a) Formula. To every 100 gallons of alcohol add:...

  16. Neglette ma essenziali: le imposte dei governi sub-nazionali. Una rassegna internazionale

    Directory of Open Access Journals (Sweden)

    G. BROSIO

    2013-10-01

    Full Text Available This work offers an updated review of the fiscal instruments available for the financing of sub-national governments. It is based essentially on the experiences observed in developing countries, however, some reference is also made to underdeveloped countries and those of the East.  JEL Codes: H21Keywords: Financing, sub-national governments, developing countries

  17. N-Phenyladamantane-1-sulfinamide

    Directory of Open Access Journals (Sweden)

    Mrityunjoy Datta

    2008-08-01

    Full Text Available In the racemic title compound, C16H21NOS, the molecules are packed into polymeric chains in the b-axis direction and are linked along the b axis by N—H...O and C—H...O hydrogen bonds.

  18. SwissProt search result: AK072740 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK072740 J023134H21 (Q93WU2) Eugenol O-methyltransferase (EC 2.1.1.146) ((Iso)eugenol... O-methyltransferase EOMT1) (S-adenosysl-L-methionine:(Iso)eugenol O-methyltransferase EOMT1) EOMT1_OCIBA 3e-67 ...

  19. SwissProt search result: AK072740 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK072740 J023134H21 (Q93WU3) Chavicol O-methyltransferase (EC 2.1.1.146) ((Iso)eugenol... O-methyltransferase CVOMT1) (S-adenosysl-L-methionine:(Iso)eugenol O-methyltransferase CVOMT1) CVMT1_OCIBA 3e-65 ...

  20. Drug: D10370 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D10370 Drug Mavatrep (USAN) C25H21F3N2O 422.1606 422.4423 D10370.gif Treatment of pain vanillo... Ion channels Related to voltage-gated cation channels Transient receptor potential family, TRPV (Vanilloid)

  1. N,N-Dimethyl-3-(1-naphthyloxy-3-(2-thienylpropan-1-amine

    Directory of Open Access Journals (Sweden)

    Jin-Tang Wang

    2008-03-01

    Full Text Available The title compound, C19H21NOS, is an intermediate for the synthesis of duloxetine hydrochloride. In the molecular structure, the thiophene and naphthalene ring systems make a dihedral angle of 87.5°. All bond lengths and angles involving heteroatoms are as expected. In the crystal structure, no classical hydrogen bonds are found.

  2. SwissProt search result: AK069229 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK069229 J023012H21 (O88704) Potassium/sodium hyperpolarization-activated cyclic nu...cleotide-gated channel 1 (Brain cyclic nucleotide gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2) HCN1_MOUSE 8e-15 ...

  3. SwissProt search result: AK069229 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK069229 J023012H21 (O88703) Potassium/sodium hyperpolarization-activated cyclic nu...cleotide-gated channel 2 (Brain cyclic nucleotide gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1) HCN2_MOUSE 4e-13 ...

  4. Drug: D07454 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D07454 Drug Amylocaine (BAN) C14H21NO2 235.1572 235.322 D07454.gif Local anesthetic... Same as: C14169 map07015 Local analgesics CAS: 644-26-8 PubChem: 51091785 LigandBox: D07454 NIKKAJI: J13.80

  5. Drug: D07572 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D07572 Drug Amylocaine hydrochloride; Dolodent (TN) C14H21NO2. HCl 271.1339 271.783 D07572.gif Local... anesthetic map07015 Local analgesics CAS: 532-59-2 PubChem: 51091891 LigandBox: D07572 NIK

  6. SwissProt search result: AK072466 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK072466 J023118H21 (Q95LA2) Dimethylaniline monooxygenase [N-oxide-forming] 1 (EC ...1.14.13.8) (Hepatic flavin-containing monooxygenase 1) (FMO 1) (Dimethylaniline oxidase 1) FMO1_CANFA 3e-14 ...

  7. SwissProt search result: AK072466 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK072466 J023118H21 (Q8K4C0) Dimethylaniline monooxygenase [N-oxide-forming] 5 (EC ...1.14.13.8) (Hepatic flavin-containing monooxygenase 5) (FMO 5) (Dimethylaniline oxidase 5) FMO5_RAT 7e-17 ...

  8. SwissProt search result: AK072466 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK072466 J023118H21 (P17635) Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC ...1.14.13.8) (Pulmonary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2) (FMO 1B1) FMO2_RABIT 1e-15 ...

  9. SwissProt search result: AK072466 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK072466 J023118H21 (P50285) Dimethylaniline monooxygenase [N-oxide-forming] 1 (EC ...1.14.13.8) (Hepatic flavin-containing monooxygenase 1) (FMO 1) (Dimethylaniline oxidase 1) FMO1_MOUSE 2e-12 ...

  10. SwissProt search result: AK072466 [KOME

    Lifescience Database Archive (English)

    Full Text Available AK072466 J023118H21 (Q8HZ70) Dimethylaniline monooxygenase [N-oxide-forming] 2 (EC ...1.14.13.8) (Pulmonary flavin-containing monooxygenase 2) (FMO 2) (Dimethylaniline oxidase 2) (FMO 1B1) FMO2_PANTR 9e-18 ...

  11. Drug: D06552 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D06552 Drug Alcaftadine (USAN/INN); Lastacaft (TN) C19H21N3O 307.1685 307.3895 D06552.gif Anti-allergic...03] S SENSORY ORGANS S01 OPHTHALMOLOGICALS S01G DECONGESTANTS AND ANTIALLERGICS S01GX Other antiallergics S0

  12. Drug: D01599 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D01599 Drug Gliclazide (JP16/INN); Glimicron (TN) C15H21N3O3S 323.1304 323.4105 D01599.gif Antidiabetic...ents affecting metabolism 396 Antidiabetic agents 3961 Sulfonylureas D01599 Glicl

  13. Drug: D00379 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D00379 Drug Tolazamide (JP16/USP/INN); Tolinase (TN) C14H21N3O3S 311.1304 311.3998 D00379.gif Antidiabetic...od Glucose Regulators Antidiabetic Agents Tolazamide D00379 Tolazamide (JP16/USP/INN) Target-based classific

  14. Drug: D10196 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D10196 Drug Ipragliflozin (INN) C21H21FO5S 404.1094 404.4518 D10196.gif Antidiabetic... [DS:H00409] sodium glucose co-transporter2 (SGLT2) inhibitor [HSA:6524] [KO:K14382] map07051 Antidiabetics

  15. Drug: D10200 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D10200 Drug Ipragliflozin L-proline (JAN) C21H21FO5S. C5H9NO2 519.1727 519.5823 D10200.gif Antidiabetic... [DS:H00409] sodium glucose co-transporter2 (SGLT2) inhibitor [HSA:6524] [KO:K14382] map07051 Antidiabetic

  16. Characterization of Contaminant Migration Potential Through In-Place Sediment Caps

    Science.gov (United States)

    2009-04-01

    Physical-Chemical Properties and Environmental Fate for Organic Chemicals. Polynuclear Aromatic Hydrocarbons, Polychlorinated Dioxins , and... biomarker (17α(H),21β(H)-hopane) will be included in the analysis in the event that it proves useful as a conservative internal marker compound. The

  17. Dicty_cDB: Contig-U15711-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available B3_G22 GQ020: Clean ROOTS systems -Diurnal... 38 0.30 2 ( DV981985 ) GQ0167.B3_H21 GQ016: Primary, secondary... SHOOT -N ... 38 0.30 2 ( DV986039 ) GQ0207.B3_C18 GQ020: Clean ROOTS systems -Diurnal... 38 0.30 2 ( AZ6931

  18. 1,5,6-Triphenyl-8-oxa-7-selena-6-phosphabicyclo[3.2.1]octane-6-selone

    Directory of Open Access Journals (Sweden)

    Yang Li

    2008-01-01

    Full Text Available The structure of the title compound, C23H21OPSe2, consists of fused puckered five- and six-membered rings, PSeC2O and C5O, respectively, with a C2O bridgehead. The C5O ring adopts a chair conformation, whilst the C2PSeO ring has an envelope conformation.

  19. Drug: D08312 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D08312 Drug Oxetorone (INN) C21H21NO2 319.1572 319.3969 D08312.gif Antimigraine ATC...SICS N02C ANTIMIGRAINE PREPARATIONS N02CX Other antimigraine preparations N02CX06 Oxetorone D08312 Oxetorone

  20. Drug: D08420 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D08420 Drug Primaquine (INN); Kanaprim (TN) C15H21N3O 259.1685 259.3467 D08420.gif Antiprotozoa...oquinolines P01BA03 Primaquine D08420 Primaquine (INN) USP drug classification [BR:br08302] Antiparasitics Antiprotozoa

  1. Drug: D05173 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D05173 Drug Nisoxetine (USAN/INN) C17H21NO2 271.1572 271.3541 D05173.gif Antidepressant Selective nora...drenalin reuptake inhibitor noradrenalin transporter inhibitor [HSA:6530] [KO:K05035] map... Solute carrier family SLC6 SLC6A2 (noradrenalin transporter) [HSA:6530] [KO:K050

  2. Characterization and virulence potential of serogroup O113 Shiga toxin-producing Escherichia coli strains isolated from beef and cattle in the United States

    Science.gov (United States)

    Shiga toxin-producing Escherichia coli (STEC) of serotype O113:H21 have caused severe diseases but are unusual in that they do not produce the intimin protein required for adherence to intestinal epithelial cells. Strains of serogroup O113 are one of the most common STEC found in ground beef and be...

  3. EST Table: FY000874 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FY000874 bmov3h21 11/11/04 65 %/109 aa ref|XP_970998.1| PREDICTED: similar to Evolution...%/109 aa gi|91094187|ref|XP_970998.1| PREDICTED: similar to Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial [Tribolium castaneum] FS756091 bmov ...

  4. EST Table: FY011605 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FY011605 rbmov3h21 11/11/04 49 %/238 aa ref|XP_970998.1| PREDICTED: similar to Evolution..._970998.1| PREDICTED: similar to Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial [Tribolium castaneum] FY016706 bmov ...

  5. Sendero Luminoso: Case Study in Insurgency

    Science.gov (United States)

    1993-01-01

    Guzman grew up in Arequipa, where he learned that violence could produce radical change. He was also influenced by the Peruvian Marxist Jose Carlos 64...16H 21. 13, Russell Watson and Brook Lamar, "It’s Your Tum to Lose," Newsweek, 28 September 1992, pp. 28~29. 14. Jorge Castaneda , "The Decline of

  6. Drug: D01465 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D01465 Drug Nizofenone fumarate (JAN); Ekonal (TN) C21H21ClN4O3. C4H4O4 528.1412 528.9416 D01465.gif Nootrop...ic; Vasodilator,cerebral Therapeutic category: 2190 ATC code: N06BX10 Thromboxane A

  7. Drug: D05830 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D05830 Drug Sermetacin (USAN/INN) C22H21ClN2O6 444.1088 444.8649 D05830.gif Anti-in...flammatory CAS: 57645-05-3 PubChem: 47207491 LigandBox: D05830 NIKKAJI: J14.534C ATOM 31 1 C8y C 22.6554 -22

  8. Deacetyl tenuazonic acid p-toluenesulfonylhydrazone

    Directory of Open Access Journals (Sweden)

    Irene Nehls

    2009-12-01

    Full Text Available The title compound {systematic name: 4-methyl-N′-[(3E-2-(1-methylpropyl-5-oxopyrrolidin-3-ylidene]benzenesulfonohydrazide}, C15H21N3O3S, is the condensation product of deacetyl tenuazonic acid (DTA and p-toluenesulfonohydrazide. The crystal structure consists of chains along [100] linked by N—H...O hydrogen bonds.

  9. (E-2,2′-[3-(2-Nitrophenylprop-2-ene-1,1-diyl]bis(3-hydroxycyclohex-2-en-1-one

    Directory of Open Access Journals (Sweden)

    Joo Hwan Cha

    2012-01-01

    Full Text Available In the title compound, C21H21NO6, each of the cyclohexenone rings adopts a half-chair conformation. Each of the pairs of hydroxy and carbonyl O atoms are oriented to allow for the formation of intramolecular O—H...O hydrogen bonds, which are typical of xanthene derivatives.

  10. 1-(Adamantan-1-yl-3-(4-fluorophenylthiourea

    Directory of Open Access Journals (Sweden)

    Nasser R. El-Brollosy

    2012-05-01

    Full Text Available In the title molecule, C17H21FN2S, the mean planes of the benzene ring and the thiourea fragment form a dihedral angle of 61.93 (9°. In the crystal, pairs of weak N—H...S interactions link the molecules, forming inversion dimers.

  11. Identification of amino acid residues involved in the interaction between measles virus Haemagglutin (MVH) and its human cell receptor (signaling lymphocyte activation molecule, SLAM).

    Science.gov (United States)

    Xu, Qin; Zhang, Peng; Hu, Chunling; Liu, Xin; Qi, Yipeng; Liu, Yingle

    2006-07-31

    Signaling lymphocyte activation molecule (SLAM; also known as CD150) is a newly identified cellular receptor for measles virus (MV). The interaction between MV Haemagglutin (MVH) and SLAM is an initial step for MV entry. We have identified several novel SLAM binding sites at residues S429, T436 and H437 of MVH protein and MVH mutants in these residues dramatically decrease the ability to interaction with the cell surface SLAM and fail to coprecipitation with SLAM in vivo as well as malfunction in syncytium formation. At the same time, K58, S59 and H61 of SLAM was also identified to be critical for MVH and SLAM binding. Further, these residues may be useful targets for the development of measles therapy.

  12. Sumoylation Inhibits the Growth Suppressive Properties of Ikaros.

    Directory of Open Access Journals (Sweden)

    Apostol Apostolov

    Full Text Available The Ikaros transcription factor is a tumor suppressor that is also important for lymphocyte development. How post-translational modifications influence Ikaros function remains partially understood. We show that Ikaros undergoes sumoylation in developing T cells that correspond to mono-, bi- or poly-sumoylation by SUMO1 and/or SUMO2/3 on three lysine residues (K58, K240 and K425. Sumoylation occurs in the nucleus and requires DNA binding by Ikaros. Sumoylated Ikaros is less effective than unsumoylated forms at inhibiting the expansion of murine leukemic cells, and Ikaros sumoylation is abundant in human B-cell acute lymphoblastic leukemic cells, but not in healthy peripheral blood leukocytes. Our results suggest that sumoylation may be important in modulating the tumor suppressor function of Ikaros.

  13. Angular momentum and topological dependence of Kepler's Third Law in the Broucke-Hadjidemetriou-H\\'enon family of periodic three-body orbits

    CERN Document Server

    Janković, Marija R

    2016-01-01

    We use 57 recently found topological satellites of Broucke-Hadjidemetriou-Henon's periodic orbits with values of the topological exponent $k$ ranging from $k$ = 3 to $k$ = 58 to plot the angular momentum $L$ as a function of the period $T$, with both $L$ and $T$ rescaled to energy $E=-\\frac12$. Upon plotting $L(T/k)$ we find that all our solutions fall on a curve that is virtually indiscernible by naked eye from the $L(T)$ curve for non-satellite solutions. The standard deviation of the satellite data from the sixth-order polynomial fit to the progenitor data is $\\sigma = 0.13$. This regularity supports Henon's 1976 conjecture that the linearly stable Broucke-Hadjidemetriou-Henon orbits are also perpetually, or Kolmogorov-Arnold-Moser stable.

  14. Hydrogenation/Dehydrogenation Performances of the MgH2-WS2 Composites

    Institute of Scientific and Technical Information of China (English)

    WANG Jiasheng; ZHANG Wei; CHENG Ying; KE Dandan; HAN Shumin

    2015-01-01

    The hydrogenation/dehydrogenation kinetics and thermodynamic behaviors of the MgH2-WS2 composites were investigated. The TPD (Temperature-Programmed-Desorption) curves showed that the onset dehydrogenation temperature of the MgH2 + 20wt% WS2 composite was 615 K, 58 K lower than that of the pristine MgH2. The kinetic measurements showed that within 21 min, the MgH2 + 20wt% WS2 composite could absorb 2.818wt% at 423 K, and release 4.244 wt% of hydrogen at 623 K, while the hydriding/dehydriding capacity of MgH2 reached only 0.979wt% and 2.319wt% respectively under identical conditions. The improvement of hydrogenation/dehydrogenation performances for the composite was attributed to the co-catalytic effect between the new phases W and MgS which formed during the ball-milling process.

  15. Dicty_cDB: AFK120 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 1.yg.ab1 QG_ABCDI lettuce salinas Lactuca sativa cDNA clone QGC16K01, mRNA sequence. 54 3e-05 2 BQ862793 |BQ...862793.1 QGC22B11.yg.ab1 QG_ABCDI lettuce salinas Lactuca sativa cDNA clone QGC22...B11, mRNA sequence. 54 3e-05 2 BQ864368 |BQ864368.1 QGC26H21.yg.ab1 QG_ABCDI lettuce salinas Lactuca sativa ...cDNA clone QGC26H21, mRNA sequence. 54 3e-05 2 BQ861698 |BQ861698.1 QGC19F15.yg.ab1 QG_ABCDI lettuce salinas

  16. Dicty_cDB: SFE493 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 6K01.yg.ab1 QG_ABCDI lettuce salinas Lactuca sativa cDNA clone QGC16K01, mRNA seq...uence. 54 3e-09 3 BQ862793 |BQ862793.1 QGC22B11.yg.ab1 QG_ABCDI lettuce salinas Lactuca sativa cDNA clone QG...C22B11, mRNA sequence. 54 3e-09 3 BQ864368 |BQ864368.1 QGC26H21.yg.ab1 QG_ABCDI lettuce salinas Lactuca sati...g.ab1 QG_ABCDI lettuce salinas Lactuca sativa cDNA clone QGC19F15, mRNA sequence. 54 3e-09 3 BW191896 |BW191...va cDNA clone QGC26H21, mRNA sequence. 54 3e-09 3 BQ861698 |BQ861698.1 QGC19F15.y

  17. Two One-Parameter Special Geometries

    CERN Document Server

    Braun, Volker; de la Ossa, Xenia

    2015-01-01

    The special geometries of two recently discovered Calabi-Yau threefolds with $h^{11}=1$ are analyzed in detail. These correspond to the 'minimal three-generation' manifolds with $h^{21}=4$ and the `24-cell' threefolds with $h^{21}=1$. It turns out that the one-dimensional complex structure moduli spaces for these manifolds are both very similar and surprisingly complicated. Both have 6 hyperconifold points and, in addition, there are singularities of the Picard-Fuchs equation where the threefold is smooth but the Yukawa coupling vanishes. Their fundamental periods are the generating functions of lattice walks, and we use this fact to explain why the singularities are all at real values of the complex structure.

  18. Synthesis and Characterization of 8-Hydroxyquinoline Derivative Containing a Triphenylamine Unit and Its Metal Complexes

    Institute of Scientific and Technical Information of China (English)

    JING, Hui-Lian; ZENG, He-Ping; ZHOU, Ya-Dong; WANG, Ting-Ting; YUAN, Guo-Zan; OUYANG, Xin-Hua

    2006-01-01

    A new 8-hydroxyquinoline derivative (5) was synthesized and characterized by ESI-MS, 1H NMR spectroscopy,elemental analysis and IR spectroscopy. The photophysical properties of compounds 5, 6 and 7 were also detemined by UV-vis and FL spectroscopy. The vibrational frequency of ligand 5 predicted by using B3LYP method is in good agreement with experimentally determined values. The compositions of the corresponding copper(Ⅱ) and zinc(Ⅱ)complexes were confirmed to be Cu(C29H21N2O)2·H2O (6) and Zn(C29H21N2O)2·H2O (7) by elementary analysis,thermogravimetry analysis and IR spectroscopy.

  19. DNA binding sites recognised in vitro by a knotted class 1 homeodomain protein encoded by the hooded gene, k, in barley (Hordeum vulgare)

    DEFF Research Database (Denmark)

    Krusell, L; Rasmussen, I; Gausing, K

    1997-01-01

    The homeodomain of the knotted classes of transcription factors from plants differs from the well characterized Antp/En type homeodomains from Drosophila at key amino acid residues contributing to the DNA binding. A cDNA, Hvh21, derived from the hooded gene and encoding a full length homolog...... of knotted1 from maize was isolated from barley seedlings and expressed as a maltose binding protein fusion in E. coli. The purified HvH21-fusion protein selected DNA fragments with 1-3 copies of the sequence TGAC. Gel shift experiments showed that the TGAC element was required for binding and the results...... further indicate that the HvH21-fusion protein binds DNA as a monomer. Udgivelsesdato: 1997-May-12...

  20. Subsolidus binary phase diagram of C10Zn-C18Zn of thermotropic phase transitions materials

    Institute of Scientific and Technical Information of China (English)

    武克忠; 王新东; 刘晓地; 左萍

    2004-01-01

    The thermotropic phase transitions layer compound in the perovskite type (n-C10 H21 NH3 )2 ZnCl4 and (nC18 H37 NH3 )2 ZnCl4 were synthesized and, at the same time, a series of rnixtures C10 Zn/C18 Zn were prepared. The experimental binary phase diagram of C10 Zn/C18 Zn was established by means of differential scanning calorimetry (DSC) and X-ray diffraction. In the phase diagram, compound (n-C10 H21 NH3 ) (n-C21 H37 NH3 )ZnCl4 and two eutectoid invariants were observed; two eutectoid temperatures are about 53 ℃ and 58 ℃. Contrasting with other similar systems, there are three noticeable solid solution ranges at the left and right boundary and middle of the phase diagram.

  1. Dicty_cDB: SSH878 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available M library Mus musculus genomic clone UUGC1M0399K06 R, DNA sequence. 48 0.076 1 BU572652 |BU572652.1 PA__Ea0001H21f Almond developing...nce. 48 0.076 1 BU573578 |BU573578.1 PA__Ea0004H03f Almond developing seed Prunus dulcis cDNA clone PA__Ea00

  2. Dicty_cDB: FC-IC0858 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available AC, RP23-158F1, complete sequence. 48 0.060 1 BU572652 |BU572652.1 PA__Ea0001H21f Almond developing...6.1 Lupinus luteus mRNA for ribosomal protein L30. 48 0.060 1 BU573578 |BU573578.1 PA__Ea0004H03f Almond developing

  3. Crystal structure of 5-chloro-3-cyclohexylsulfinyl-2,4,6-trimethyl-1-benzofuran

    Directory of Open Access Journals (Sweden)

    Hong Dae Choi

    2014-09-01

    Full Text Available In the title compound, C17H21ClO2S, the cyclohexyl ring adopts a chair conformation with the C—S bond in an equatorial orientation. In the crystal, molecules are linked by C—H...O and C—H...π hydrogen bonds and a Cl...π [3.594 (2 Å] contact into chains along the a-axis direction.

  4. 5-Cyclohexyl-2-(3-fluorophenyl-3-methylsulfinyl-1-benzofuran

    Directory of Open Access Journals (Sweden)

    Hong Dae Choi

    2012-04-01

    Full Text Available In the title compound, C21H21FO2S, the cyclohexyl ring adopts a chair conformation. The 3-fluorophenyl ring makes a dihedral angle of 38.38 (6° with the mean plane [r.m.s. deviation = 0.010 (1 Å] of the benzofuran fragment. In the crystal, molecules are linked by weak C—H...O hydrogen bonds.

  5. Drug: D06303 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D06303 Drug Vincofos (USAN/INN) C11H21Cl2O4P 318.0555 319.1618 D06303.gif Anthelmin...tic CAS: 17196-88-2 PubChem: 47207960 LigandBox: D06303 NIKKAJI: J9.078F ATOM 18 1 C1b C 21.2292 -17.8938 2

  6. Dicty_cDB: AFK872 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ACR23H21, complete sequence. 42 0.051 6 AI484136 |AI484136.1 EST248943 tomato resistant, Cornell Lycopersico...12 2 AI490786 |AI490786.1 EST241494 tomato shoot, Cornell Lycopersicon esculentum cDNA clone cLEB3H9 similar... AI773934 |AI773934.1 EST255034 tomato resistant, Cornell Lycopersicon esculentum cDNA clone cLER8N1, mRNA s

  7. Dicty_cDB: CFG834 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available one BACR23H21, complete sequence. 42 0.038 6 AI484136 |AI484136.1 EST248943 tomato resistant, Cornell Lycope...38 0.10 2 AI490786 |AI490786.1 EST241494 tomato shoot, Cornell Lycopersicon esculentum cDNA clone cLEB3H9 si....10 2 AI773934 |AI773934.1 EST255034 tomato resistant, Cornell Lycopersicon esculentum cDNA clone cLER8N1, m

  8. 2-[5-(4-Methoxyphenyl-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl]-6-methyl-1,3-benzothiazole

    Directory of Open Access Journals (Sweden)

    Hoong-Kun Fun

    2011-09-01

    Full Text Available In the title compound, C24H21N3OS, the pyrazole ring makes dihedral angles of 5.40 (7 and 6.72 (8° with the benzo[d]thiazole ring system and the benzene ring, respectively, and a dihedral angle of 85.72 (8° with the methoxy-substituted benzene ring. In the crystal structure, the molecules are linked by C—H...π interactions.

  9. Drug: D10112 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D10112 Drug Dexmecamylamine hydrochloride (USAN) C11H21N. HCl 203.1441 203.7521 D10112.gif Treatment of major depressive disorder nicotinic cholinergic receptor alpha4beta2 antagonist [HSA:11...04813] Dexmecamylamine D10112 Dexmecamylamine hydrochloride (USAN) CAS: 107596-30-5 PubChem: 135626830 LigandBox: D1011...s Cys-loop superfamily Acetylcholine (nicotinic) alpha4beta2 nicotinic receptor [HSA:1137 1141] [KO:K04806 K

  10. Drug: D10111 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D10111 Drug Dexmecamylamine (USAN) C11H21N 167.1674 167.2911 D10111.gif Treatment o...ily Acetylcholine (nicotinic) alpha4beta2 nicotinic receptor [HSA:1137 1141] [KO:K04806 K04813] Dexmecamylamine D1011...1 Dexmecamylamine (USAN) CAS: 107538-05-6 PubChem: 135626829 LigandBox: D10111 ATOM 12 1 C1z C 25.1

  11. 2-[(1RS,3RS,3aRS,6aSR-5-Benzyl-4,6-dioxo-3-phenyloctahydropyrrolo[3,4-c]pyrrol-1-yl]acetamide

    Directory of Open Access Journals (Sweden)

    Konstantin V. Kudryavtsev

    2011-12-01

    Full Text Available In the title compound, C21H21N3O3, the relative stereochemistry of the four stereogenic C atoms has been determined. The dihedral angle between the phenyl rings is 77.63 (7°. In the crystal, ribbons spread along the a axis are formed by N—H...O hydrogen bonds. C—H...π interactions also occur.

  12. Drug: D01208 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D01208 Drug Aluminum clofibrate (JAN/INN); Alfibrate (TN) C20H21AlCl2O7 470.048 471...GENTS C10A LIPID MODIFYING AGENTS, PLAIN C10AB Fibrates C10AB03 Aluminium clofibrate D01208 Aluminum clofibr...tivated receptor (PPAR) alpha [HSA:5465] [KO:K07294] Aluminium clofibrate [ATC:C10AB03] D01208 Aluminum clof

  13. (Isopropylamino(methyldiphenylphosphonium iodide

    Directory of Open Access Journals (Sweden)

    Normen Peulecke

    2011-07-01

    Full Text Available The title compound, C16H21NP+·I−, was obtained by the reaction of Ph2PN(iPrP(PhN(iPrH with MeI involving cleavage of one of the P—N bonds in diethyl ether. The two phenyl rings form a dihedral angle of 82.98 (5°. A weak donor–acceptor N—H...I interaction is observed.

  14. Methyl 4,5-diacetoxy-1-oxo-2-phenylperhydro-4,6-epoxycyclopenta[c]pyridine-7-carboxylate ethanol solvate

    Directory of Open Access Journals (Sweden)

    Victor N. Khrustalev

    2009-12-01

    Full Text Available The title compound, the product of an acid-catalysed Wagner–Meerwein skeletal rearrangement, crystallizes as an ethanol monosolvate, C20H21NO8·C2H6O. The title molecule comprises a fused tricyclic system containing two five-membered rings (cyclopentane and tetrahydrofuran in the usual envelope conformations and one six-membered ring (piperidinone adopting a flattened twist–boat conformation.

  15. Drug: D10171 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D10171 Drug Tedatioxetine hydrobromide (USAN) C18H21NS. HBr 363.0656 364.343 D10171...-receptor [HSA:3358] [KO:K04157] Tedatioxetine D10171 Tedatioxetine hydrobromide (USAN) 5-HT3-receptor [HSA:...3359 9177 170572 200909 285242] [KO:K04819] Tedatioxetine D10171 Tedatioxetine hydrobromide... [KO:K08155] [TC:2.A.1.2.29] Tedatioxetine D10171 Tedatioxetine hydrobromide (USAN) CAS: 960151-65-9 PubChem

  16. Drug: D01879 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D01879 Drug Eptazocine hydrobromide (JAN); Sedapain (TN) C15H21NO. HBr 311.0885 312...l nervous system 114 Antipyretics and analgesics, anti-inflammatory agents 1149 Others D01879 Eptazocine hydrobromide...ed receptors Rhodopsin family Opioid mu-opioid receptor [HSA:4988] [KO:K04215] Eptazocine D01879 Eptazocine hydrobromide... (JAN) kappa-opioid receptor [HSA:4986] [KO:K04214] Eptazocine D01879 Eptazocine hydrobromide (J

  17. Drug: D00822 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D00822 Drug Citalopram hydrobromide (USAN); Celexa (TN) C20H21FN2O. HBr 404.09 405....06AB Selective serotonin reuptake inhibitors N06AB04 Citalopram D00822 Citalopram hydrobromide (USAN) USP dr...n and Norepinephrine Reuptake Inhibitors) Citalopram D00822 Citalopram hydrobromide...serotonin transporter) [HSA:6532] [KO:K05037] Citalopram [ATC:N06AB04] D00822 Citalopram hydrobromide (USAN)

  18. Drug: D07102 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D07102 Drug Alizapride (INN); Plitican (TN) C16H21N5O2 315.1695 315.3702 D07102.gif... DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS A03F PROPULSIVES A03FA Propulsives A03FA05 Alizapride D07102 Alizapride...amily Dopamine dopamine D2-receptor [HSA:1813] [KO:K04145] Alizapride [ATC:A03FA05] D07102 Alizapride

  19. Drug: D06656 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D06656 Drug Tezampanel (USAN); Tezampanel hydrate C13H21N5O2. H2O 297.1801 297.3534... receptor [HSA:2897 2898 2899 2900 2901] [KO:K05201 K05202 K05203 K05204 K05205] Tezampanel D06656 Tezampanel... (USAN) AMPA receptor [HSA:2890 2891 2892 2893] [KO:K05197 K05198 K05199 K05200] Tezampanel D06656 Tezampanel

  20. (Isopropyl­amino)(meth­yl)diphenyl­phospho­nium iodide

    Science.gov (United States)

    Peulecke, Normen; Peitz, Stephan; Müller, Bernd H.; Spannenberg, Anke; Rosenthal, Uwe

    2011-01-01

    The title compound, C16H21NP+·I−, was obtained by the reaction of Ph2PN(iPr)P(Ph)N(iPr)H with MeI involving cleavage of one of the P—N bonds in diethyl ether. The two phenyl rings form a dihedral angle of 82.98 (5)°. A weak donor–acceptor N—H⋯I inter­action is observed. PMID:21837129

  1. Drug: D08343 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available st [HSA:4988] [KO:K04215] hsa04080(4988) Neuroactive ligand-receptor interaction map07028 Antipsychotics map07039 Opioid analgesic...3327 D08343.gif Opioid analgesic Same as: C07128 ATC code: N02AB02 Synthesis opioid mu-opioid receptor agoni...D08343 Drug Pethidine (INN); Meperidine; Pethidine DBL (TN) C15H21NO2 247.1572 247.

  2. Bromido(2-{1-[2-(piperidin-1-ylethylimino]ethyl}phenolatocopper(II

    Directory of Open Access Journals (Sweden)

    Xiao-Fan Zhao

    2010-08-01

    Full Text Available In the title complex, [CuBr(C15H21N2O], the CuII atom is coordinated by one phenolate O, one imine N and one amine N atom of the tridentate Schiff base ligand and by one bromide ion, resulting in a distorted CuBrN2O square-planar geometry for the metal ion, with the N atoms in a cis conformation.

  3. Spectroscopic investigation of phase transitions in 1-nonanol and 1-decanol

    CERN Document Server

    Chernolevska, Yelyzaveta; Pogorelov, Valeriy; Doroshenko, Iryna; Doroshenko, Olena; Sablinskas, Valdas; Balevicius, Vytautas

    2016-01-01

    FTIR spectra of monohydric alcohols 1-nonanol (C9H19OH) and 1-decanol (C10H21OH) were registered in the spectral region from 500 cm-1 to 4000 cm-1 at temperatures from -50 to + 25 {\\deg}C for 1-nonanol and +100 {\\deg}C for 1-decanol. Temperature-induced spectra changes were compared for these two alcohols. The authors link the observed changes with the transformations of cluster structure occurring during phase transitions.

  4. Dicty_cDB: Contig-U16289-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available LX4a46b02f1 250DPH (..) Rutilus rutilus cDNA cl... 84 1e-22 3 ( EG534235 ) RrLX4a46h21f1 250DPH (..) Rutilus...... 100 1e-22 3 ( BG260500 ) 602372044F1 NIH_MGC_93 Homo sapiens cDNA clone IM... 70 1e-22 4 ( EG534067 ) Rr

  5. Drug: D08288 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D08288 Drug Nortriptyline (INN); Nortrilen (TN) C19H21N 263.1674 263.3767 D08288.gif Antidepress...ant, tricyclic Same as: C07274 ATC code: N06AA10 Tricyclic antidepressants serotonin transporte... Serotonergic synapse Enzyme: CYP2D6 [HSA:1565] Genomic biomarker: CYP2D6 [HSA:1565] map07027 Antidepress... D08288 Nortriptyline (INN) USP drug classification [BR:br08302] Antidepressants Tricyclics Nortriptyline D0

  6. Drug: D08124 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D08124 Drug Levosalbutamol (INN) C13H21NO3 239.1521 239.3107 D08124.gif Antiasthmat...onists R03AC02 Salbutamol D08124 Levosalbutamol (INN) R03C ADRENERGICS FOR SYSTEM...IC USE R03CC Selective beta-2-adrenoreceptor agonists R03CC02 Salbutamol D08124 Levosalbutamol (INN) Target-...energic receptor [HSA:154] [KO:K04142] Levosalbutamol D08124 Levosalbutamol (INN)

  7. Drug: D08174 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D08174 Drug Memantine (INN); Exiba (TN) C12H21N 179.1674 179.3018 D08174.gif Anti-Alzhe...imer's [DS:H00056] Same as: C13736 ATC code: N06DX01 Indication: Alzheimer's disease adamantane derivati...napse hsa05010(2902+2903+2904+2905+2906) Alzheimer's disease Transporter: SLC22A2 [HSA:6582] map07056 Agents for Alzhe

  8. The Voronoi Diagram for the Euclidean Traveling Salesman Problem Is Piecemeal Quartic and Hyperbolic

    Science.gov (United States)

    1990-06-01

    ceiling function is of cubic order as predicted by the analysis. Acknowledgments The research has greatly benefited from discussions with Gerald ...The Science of Computing. Exploring tole Nature and Power of Algorithms. Addison-Wesley. Reading MA. � 1989 [H21 Held, M . and R M Karp , "The...34Traveling salesman cycles are not always subgrapris of Voronoi duals", Information Processing .etters 16(l):11-12. January 1983. (K21 Karp , R.M

  9. Drug: D00652 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D00652 Drug Brinzolamide (JAN/USP/INN); Azopt (TN) C12H21N3O5S3 383.0643 383.5072 D00652.gif Antiglaucoma...(760+762) Proximal tubule bicarbonate reclamation map07054 Antiglaucoma agents Th...amide D00652 Brinzolamide (JAN/USP/INN) USP drug classification [BR:br08302] Ophthalmic Agents Ophthalmic Antiglaucoma

  10. Early Attachment Sites for Shiga-toxigenic Escherichia coli O157:H7 in Experimentally Inoculated Weaned Calves

    Science.gov (United States)

    Weaned 3-to- 4-month-old calves were fasted 48 h, inoculated with 10**10 CFU of Shiga toxin-positive Escherichia coli (STEC) O157:H7 strain 86-24 (STEC O157) or STEC O91:H21 strain B2F1 (STEC O91), Shiga toxin-negative E. coli O157:H7 strain 87-23 (Stx**- O157), or non-pathogenic control E. coli, ne...

  11. Heavyweight Dendritic Inks for Positive Microcontact Printing

    NARCIS (Netherlands)

    Perl, András; Peter, Mária; Ravoo, Bart Jan; Reinhoudt, David N.; Huskens, Jurriaan

    2006-01-01

    Poly(propylene imine) dendrimers with dialkyl sulfide end groups were prepared and developed as inks for positive microcontact printing ((+)uCP) on gold. Long (C10H21-S-C10H20-), medium (C3H7-S-C4H8-), and short (CH3-S-CH2-) dialkyl sulfide end groups were attached to second- and third-generation PP

  12. Drug: D01665 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D01665 Drug Voglibose (JP16/USAN/INN); Basen (TN) C10H21NO7 267.1318 267.2762 D01665.gif Antidiabetic...se metabolism hsa04973(8972) Carbohydrate digestion and absorption map07051 Antidiabetics Therapeutic catego...ry of drugs in Japan [BR:br08301] 3 Agents affecting metabolism 39 Other agents affecting metabolism 396 Antidiabetic

  13. (2,6-Diisopropyl-phen-yl)(2-thienylmethyl-ene)amine.

    Science.gov (United States)

    Imhof, Wolfgang

    2009-02-25

    The title compound, C(17)H(21)NS, was prepared by the condensation of thio-phene-2-carbaldehyde with 2,6-diiso-propyl-aniline. It crystallizes with two mol-ecules in the asymmetric unit. The mol-ecules are inter-connected via a C-H⋯N hydrogen bond. The dihedral angles between the thio-phene and phenyl rings are 81.7 (7) and 85.5 (7)°.

  14. Occurrence and characterization of Shiga toxin-producing Escherichia coli O157:H7 and other non-sorbitol-fermenting E. coli in cattle and humans in urban areas of Morogoro, Tanzania

    DEFF Research Database (Denmark)

    Lupindu, Athumani M; Olsen, John Elmerdahl; Ngowi, Helena A

    2014-01-01

    effects on Vero cells. The prevalence of STEC in cattle was 1.6%, out of which 0.9% was serotype O157:H7 and the overall prevalence of diarrheagenic E. coli in cattle was 2.2%. The serotypes O157:H7, O142:H34, O113:H21, O+:H-, O+:H16, and O25:H4 were identified. One ESBL-producing isolate showed the MLST...

  15. Drug: D07642 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D07642 Drug Cefminox (INN); CMNX C16H21N7O7S3 519.0665 519.5756 D07642.gif Antibiotic, cephalosporin... ATC code: J01DC12 Semisynthetic cephalosporin: broad spectrum cephalosporin penicillin bin... SYSTEMIC USE J01 ANTIBACTERIALS FOR SYSTEMIC USE J01D OTHER BETA-LACTAM ANTIBACTERIALS J01DC Second-generation cephalosporin

  16. EST Table: FS743730 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS743730 E_FL_bmmt_26H21_R_0 10/09/28 49 %/178 aa gb|ACN52067.1| insect intestinal mucin 3 [Mamestra configu...rata] 10/09/07 n.h 10/08/28 n.h 10/09/10 n.h 10/09/10 n.h 10/09/10 n.h FS740161 bmmt ...

  17. 30 aastat pärast diktatuuri hukku pole rahu Hispaaniasse naasnud / Priit Kivi

    Index Scriptorium Estoniae

    Kivi, Priit

    2005-01-01

    Ilmunud ka: Postimees : na russkom jazõke Ajal. Postimees : na russkom jazõke lüh. 21. nov., lk 11. Hispaania paremäärmuslased süüdistavad sotsialistlikku valitsust riigi tahtlikus lõhkumises. Franco-kummardajate terava vastuseisu on pälvinud valitsuse toetus samasooliste abielule, Kataloonia iseseisvuspüüdluste toetamine ning planeeritav õppekava, mis vähendab usuõpetuse tähtsust koolides. Lisa: Kindral Francisco Franco

  18. 1,5-Dimethyl-4-(1-methyl-3-oxo-3-phenylprop-1-enylamino-2-phenyl-1H-pyrazol-3(2H-one

    Directory of Open Access Journals (Sweden)

    Hualing Zhu

    2011-07-01

    Full Text Available In the title compound, C21H21N3O2, an intramolecular N—H...O interaction generates an S(6 ring, which stablizes the enamine–keto tautomer. The S(6 ring makes dihedral angles of 33.07 (7, 56.50 (8 and 38.59 (8°, respectively, with the benzoylacetone benzene ring and the antipyrine pyrazole and benzene rings.

  19. 1-[Morpholino(phenylmethyl]-2-naphthol

    Directory of Open Access Journals (Sweden)

    Min Min Zhao

    2010-06-01

    Full Text Available There are two independent molecules in the asymmetric unit of the title compound, C21H21NO2, which was synthesized by the one-pot reaction of 2-naphthol, morpholine and benzaldehyde. The dihedral angles between the naphthalene ring systems and the benzene rings are 84.03 (7 and 75.76 (8° in the two molecules and an intramolecular O—H...N hydrogen bond occurs in each independent molecule.

  20. Heat resistance of Fe-Al intermetallics in the context of selected heat-resistant and hihg-temperature creep resistant steels

    Directory of Open Access Journals (Sweden)

    P. Baranowski

    2009-04-01

    Full Text Available Results are hereby presented of heat-resistance tests of two Fe3Al and FeAl intermetallic phase-based alloys in the context of St41k-typeboiler steel and 50H21G9N4 high-temperature creep resistant steel. It has been ascertained that heat resistance of the 50H21G9N4 steeland of the Fe3Al and FeAl intermetallic phase-based alloys significantly exceeds that of the boiler steel tested in the air atmosphere and the atmosphere of a flue gas with CO, CO2, SiO2 content alike. Improvement of these properties depends of exposure conditions. The largest differences have been observed when the tests were carried out in temperature 1023 K and in the flue gas atmosphere. The differences have been more and more noticeable as the exposition duration extended. A tendency has been also recorded of smaller mass decrements of the Fe3Al and FeAl intermetallic phase-based alloys as compared to the 50H21G9N4 steel.

  1. Stabilizing Effect of a Double-Harmonic RF System in the CERN PS

    CERN Document Server

    Bhat, C M; Damerau, H; Hancock, S; Mahner, E; Zimmermann, F

    2010-01-01

    Motivated by the discussions on scenarios for LHC upgrades, beam studies on the stability of flat bunches in a double-harmonic RF system have been conducted in the CERN Proton Synchrotron (PS). Injecting nearly nominal LHC beam intensity per cycle, 18 bunches are accelerated on harmonic h=21 to 26 GeV with the 10 MHz RF system. On the flat-top, all bunches are then transformed to flat bunches by adiabatically adding RF voltage at h=42 from a 20 MHz cavity in anti-phase to the h=21 system. The voltage ratio V(h42)/V(h21) of about 0.5 was set according to simulations. For the next 140 ms,longitudinal profiles show stable bunches in the double harmonic RF bucket until extraction. Without the second harmonic component, coupled-bunch oscillations are observed. The flatness of the bunches along the batch is analyzed as a measure of the relative phase error between the RF systems due to beam loading. Measurements of electron cloud effects induced by the beam are also discussed. The results of beam dynamics simulatio...

  2. Stabilizing effect of a double-harmonic RF system in the CERN PS

    CERN Document Server

    Bhat, C M; Damerau, H; Hancock, S; Mahner, E; Zimmermann, F

    2010-01-01

    Motivated by the discussions on scenarios for LHC upgrades, beam studies on the stability of flat bunches in a double-harmonic RF system have been conducted in the CERN Proton Synchrotron (PS). Injecting nearly nominal LHC beam intensity per cycle, 18 bunches are accelerated on harmonic h = 21 to 26GeV with the 10MHz RF system. On the flat-top, all bunches are then transformed to flat bunches by adiabatically adding RF voltage at h = 42 from a 20MHz cavity in anti-phase to the h = 21 system. The voltage ratio V (h42)/V (h21) of about 0.5 was set according to simulations. For the next 140 ms, longitudinal profiles show stable bunches in the double-harmonic RF bucket until extraction. Without the second harmonic component, coupled-bunch oscillations are observed. The flatness of the bunches along the batch is analyzed as a measure of the relative phase error between the RF systems due to beam loading. The results of beam dynamics simulations and their comparison with the measured data are presented.

  3. STABILIZING EFFECT OF A DOUBLE-HARMONIC RF SYSTEM IN THE CERN PS

    CERN Document Server

    Bhat, C M; Damerau, H; Hancock, S; Mahner, E; Zimmermann, F

    2009-01-01

    Motivated by the discussions on scenarios for LHC upgrades, beam studies on the stability of flat bunches in a double-harmonic RF system have been conducted in the CERN Proton Synchrotron (PS). Injecting nearly nominal LHC beam intensity per cycle, 18 bunches are accelerated on harmonic h = 21 to 26GeV with the 10MHz RF system. On the flat-top, all bunches are then transformed to flat bunches by adiabatically adding RF voltage at h = 42 from a 20MHz cavity in anti-phase to the h = 21 system. The voltage ratio V (h42)/V (h21) of about 0.5 was set according to simulations. For the next 140 ms, longitudinal profiles show stable bunches in the double-harmonic RF bucket until extraction. Without the second harmonic component, coupled-bunch oscillations are observed. The flatness of the bunches along the batch is analyzed as a measure of the relative phase error between the RF systems due to beam loading. The results of beamdynamics simulations and their comparison with the measured data are presented.

  4. 萘基桥联有机-无机杂化介孔材料的合成及其光学性质%Synthesis and Optical Properties of Organic-Inorganic Hybrid Mesoporous Materials with Naphthalene Bridging Groups

    Institute of Scientific and Technical Information of China (English)

    崔小燕; 韩书华; 孙元元; 王莎莎; 邱晓勇; 高萌

    2013-01-01

    Ordered naphthalene-bridged hybrid periodic mesoporous organosilicas (PMOs) were synthesized by co-condensation of 2,7-bis(3-triethoxysilylpropylaminocarbonyloxy) naphthalene (NIS) and tetraethoxy orthosilane (TEOS) using cationic trimeric surfactant [C10H21N +(CH3)2(CH2)2N +(CH3) (C10H21)-(CH2)2N+(CH3)2C10H21]·3Br- as a structure-directing agent. The resulting samples were characterized by powder X-ray diffraction, high resolution transmission electron microscopy, nitrogen adsorption-desorption, and differential scanning calorimetry/thermogravimetric analysis. Ordered mesoporous hybrid materials with a crystal-like pore wal formed when the molar ratio of NIS to the sum of NIS and TEOS was 40%. When this value is below or above 40%, ordered mesoporous hybrid materials with amorphous phase in the pore wal s, and nonporous hybrid materials are obtained, respectively. As the number of naphthyl groups in the pore wal s increases, the thermal stability of the hybrid materials is enhanced through the strongπ-πinteractions between organic groups. Because of the fluorescent naphthyl groups in the silica framework, the PMOs exhibit optical behavior consistent with excimer formation. Absorption spectra of the PMOs show blue shifts compared with that of the precursor (NIS), suggesting the formation of aggregates in the pore wal s of the hybrid materials. As the molar ratio of NIS to the sum of NIS and TEOS increases, the fluorescence quantum yield of the PMOs decreases through fluorescence quenching caused by aggregation of naphthyl groups.%  以短链阳离子三聚表面活性剂[C10H21N+(CH3)2(CH2)2N+(CH3)(C10H21)(CH2)2N+(CH3)2C10H21]·3Br-为结构导向剂,通过2,7-二(3-三乙氧硅基氨丙酯基)萘(NIS)和四乙氧基硅烷(TEOS)共缩聚,制备了有序的萘基桥联的杂化周期性介孔有机硅(PMOs)。样品通过X射线衍射(XRD)、高分辨透射电镜(HRTEM)、氮气吸附-脱附、差示扫描量热/热重分析(DSC/TGA)表征

  5. La riduzione dei tassi dell'interesse

    Directory of Open Access Journals (Sweden)

    P. SYLOS LABINI

    2013-10-01

    Full Text Available The article considers the effects of raising the tax rate on gross interest payments on public bonds in Italy. Several economists have suggested that such a measure is a duplication devoid of real effects because, given the demand for such bonds, the State would be forced to increase the gross interest payment by exactly the same amount it collects by raising the tax rate. By contrast, the author claims that such a measure would provide a net cash benefit for the public finances.  JEL Codes: E43, H21, H63Keywords: Tax rates, interest payments, Italy, public finances

  6. 5-(Anthracen-9-yl-3-(4-nitrophenyl-1-phenyl-4,5-dihydro-1H-pyrazole

    Directory of Open Access Journals (Sweden)

    Bao-Li Dong

    2010-11-01

    Full Text Available In the title compound, C29H21N3O2, the five-membered pyrazoline ring is nearly planar, the maximum deviation being 0.037 (3 Å. The anthracene ring system is approximately perpendicular to the central pyrazoline ring, making a dihedral angle of 86.55 (16°, whereas the two attached benzene rings are oriented at smaller dihedral angles of 12.9 (2 and 14.7 (2°with respect to the pyrazoline ring. An intramolecular C—H...N hydrogen bond is observed.

  7. 5-Cyclohexyl-3-(4-fluorophenylsulfinyl-2-methyl-1-benzofuran

    Directory of Open Access Journals (Sweden)

    Hong Dae Choi

    2011-04-01

    Full Text Available In the title compound, C21H21FO2S, the cyclohexyl ring adopts a chair conformation. The 4-fluorophenyl ring makes a dihedral angle of 83.55 (4° with the mean plane of the benzofuran fragment. In the crystal, molecules are linked through weak intermolecular C—H...O and C—H...π interactions. The crystal structure also exhibits aromatic π–π interactions between the furan rings of neighbouring molecules [centroid–centroid distance = 3.541 (2 Å].

  8. Diethylenetriaminium hexafluoridotitanate(IV fluoride

    Directory of Open Access Journals (Sweden)

    J. Lhoste

    2008-11-01

    Full Text Available The title compound, (C6H21N4[TiF6]F, was synthesized by the reaction of TiO2, tris(2-aminoethylamine, HF and ethanol at 463 K in a microwave oven. The crystal structure consists of two crystallographically independent [TiF6]2− anions, two fluoride anions and two triply-protonated tris(2-aminoethylamine cations. The Ti atoms are coordinated by six F atoms within slightly distorted octahedra. The anions and cations are connected by intermolecular N—H...F hydrogen bonds.

  9. N-(2-Chlorophenyl-2-({5-[4-(methylsulfanylbenzyl]-4-phenyl-4H-1,2,4-triazol-3-yl}sulfanylacetamide

    Directory of Open Access Journals (Sweden)

    Hoong-Kun Fun

    2011-08-01

    Full Text Available In the title molecule, C24H21ClN4OS2, the central 1,2,4-triazole ring forms dihedral angles of 89.05 (9, 86.66 (9 and 82.70 (10° with the chloro-substituted benzene ring, the methylsulfanyl-substituted benzene ring and the phenyl ring, respectively. In the crystal, molecules are linked into sheets parallel to (100 by intermolecular N—H...N and weak C—H...O hydrogen bonds.

  10. Dicty_cDB: AFI627 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 19D15 5' sequence, mRNA sequence. 38 0.12 2 AI490786 |AI490786.1 EST241494 tomato shoot, Cornell Lycopersico...e, mRNA sequence. 38 0.12 2 AI773934 |AI773934.1 EST255034 tomato resistant, Cornell Lycopersicon esculentum...11252.5 Drosophila melanogaster clone BACR23H21, complete sequence. 42 0.058 6 AI484136 |AI484136.1 EST248943 tomato resistant, Corne...ll Lycopersicon esculentum cDNA clone cLER1C5, mRNA sequence. 38 0.12 2 BG128254 |B

  11. Quantification of compositional changes of petroleum hydrocarbons by GC/FID and GC/MS during a long-term bioremediation experiment

    DEFF Research Database (Denmark)

    Jensen, Trine S.; Arvin, Erik; Svensmark, Bo;

    2000-01-01

    Samples from a long-term bioremediation experiment contaminated with two crude oils, Arabian Heavy and Gullfax, was used to analyze the compositional change of petroleum hydrocarbons. A time course of five different homologous series of petroleum hydrocarbons were analysed by GC/FID and GC......, that is, nor-hopanes, hopanes, methyl-hopanes, steranes, mono- og triaromatic steranes. The 17 alpha (H),21 beta (H)-hopane was found to be stable toward biodegradation and was used as reference compound The internal standard quantification method was used to quantify changes of the homologous series...... biodegradation occurs....

  12. Drug: D00415 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D00415 Drug Zolmitriptan (JAN/USAN/INN); Zomig (TN) C16H21N3O2 287.1634 287.3568 D0...asoconstrictors 2160 Vasoconstrictors D00415 Zolmitriptan (JAN/USAN/INN) Anatomic...PREPARATIONS N02CC Selective serotonin (5HT1) agonists N02CC03 Zolmitriptan D00415 Zolmitriptan (JAN/USAN/IN...d Receptor Agonists Zolmitriptan D00415 Zolmitriptan (JAN/USAN/INN) Target-based classification of drugs [BR...:br08310] G Protein-coupled receptors Rhodopsin family Serotonin 5-HT1B-receptor [HSA:3351] [KO:K04153] Zolmitriptan

  13. Drug: D00451 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D00451 Drug Sumatriptan (JAN/USP/INN); Imigran (TN); Imitrex (TN) C14H21N3O2S 295.1...216 Vasoconstrictors 2160 Vasoconstrictors D00451 Sumatriptan (JAN/USP/INN) Anato...NE PREPARATIONS N02CC Selective serotonin (5HT1) agonists N02CC01 Sumatriptan D00451 Sumatriptan (JAN/USP/IN...d Receptor Agonists Sumatriptan D00451 Sumatriptan (JAN/USP/INN) Target-based classification of drugs [BR:br...08310] G Protein-coupled receptors Rhodopsin family Serotonin 5-HT1B-receptor [HSA:3351] [KO:K04153] Sumatriptan

  14. Drug: D07465 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D07465 Drug Arotinolol (INN) C15H21N3O2S3 371.0796 371.5411 D07465.gif Antiarrhythmic alpha1-adr...energic receptor antagonist [HSA:146 147 148] [KO:K04137 K04136 K04135]; beta1-adrenergic recep...tor antagonist [HSA:153] [KO:K04141]; beta2-adrenergic receptor antagonist [HSA:154] [KO:K04142]; beta3-adre...61(146+147+148+153+154) Adrenergic signaling in cardiomyocytes hsa04270(146+147+148) Vascular smooth muscle ...contraction hsa04970(146+147+148+153+154+155) Salivary secretion map07214 beta-Adr

  15. Drug: D02147 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D02147 Drug Albuterol (USP); Salbutamol; Proventil (TN) C13H21NO3 239.1521 239.3107... D02147.gif Bronchodilator [DS:H00079] ATC code: R03AC02 R03CC02 beta2-adrenergic receptor agonist [HSA:154]...3A ADRENERGICS, INHALANTS R03AC Selective beta-2-adrenoreceptor agonists R03AC02 Salbutamol D02147 Albuterol... (USP); Salbutamol R03C ADRENERGICS FOR SYSTEMIC USE R03CC Selective beta-2-adren...oreceptor agonists R03CC02 Salbutamol D02147 Albuterol (USP); Salbutamol USP drug classification [BR:br08302

  16. Drug: D01830 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D01830 Drug Arotinolol hydrochloride (JP16); Almarl (TN) C15H21N3O2S3. HCl 407.0563... 408.0021 D01830.gif Antihypertensive Therapeutic category: 2123 alpha1-adrenergic receptor antagonist [HSA:...146 147 148] [KO:K04137 K04136 K04135]; beta1-adrenergic receptor antagonist [HSA:153] [KO:K04141]; beta2-adr...energic receptor antagonist [HSA:154] [KO:K04142]; beta3-adrenergic receptor ant...48+153+154+155) Neuroactive ligand-receptor interaction hsa04261(146+147+148+153+154) Adrenergic signaling i

  17. EST Table: FS730301 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS730301 E_FL_bmmt_18H21_F_0 10/09/28 96 %/137 aa ref|NP_731941.1| effete [Drosophi...la melanogaster] ref|NP_001119686.1| effete [Acyrthosiphon pisum] ref|XP_310998.2| AGAP000145-PA [Anopheles ...protein ligase) (Ubiquitin carrier protein) (Protein effete) [Tribolium castaneum...AltName: Full=Ubiquitin-protein ligase; AltName: Full=Ubiquitin carrier protein; AltName: Full=Protein effet...e emb|CAA44453.1| ubiquitin-conjugating enzyme [Drosophila melanogaster] gb|AAF55093.1| effet

  18. Drug: D01428 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D01428 Drug Fenoterol hydrobromide (JAN); Berotec (TN) C17H21NO4. HBr 383.0732 384....ividual organs 22 Respiratory organ agents 225 Bronchodilators 2252 Isoprenalines D01428 Fenoterol hydrobromide...-adrenoreceptor agonists R03AC04 Fenoterol D01428 Fenoterol hydrobromide (JAN) R03C ADRENERGICS FOR SYSTEMIC... USE R03CC Selective beta-2-adrenoreceptor agonists R03CC04 Fenoterol D01428 Fenoterol hydrobromide...psin family Adrenaline beta2-adrenergic receptor [HSA:154] [KO:K04142] Fenoterol [ATC:G02CA03] D01428 Fenoterol hydrobromide

  19. Ethyl 2-(1,2,3,4-tetrahydrospiro[carbazole-3,2′-[1,3]dioxolan]-9-ylacetate

    Directory of Open Access Journals (Sweden)

    Philipp M. G. Löffler

    2009-04-01

    Full Text Available In the title compound, C18H21NO4, the hydrogenated six-membered ring of the carbazole unit adopts a half-chair conformation. The dioxolane ring and ethylacetate substituent point to opposite sides of the carbazole plane. The ethylacetate substituent adopts an essentially fully extended conformation, and its mean plane forms a dihedral angle of 83.8 (1° with respect to the carbazole mean plane. The molecules are arranged into stacks in which the carbazole planes form a dihedral angle of 4.4 (1° and have an approximate interplanar separation of 3.6 Å.

  20. [(4-Methylbenzylbis(pyridin-2-ylmethylamine-κ3N,N′,N′′]bis(thiocyanato-κScopper(II dichloromethane hemisolvate

    Directory of Open Access Journals (Sweden)

    Yan Qi

    2012-04-01

    Full Text Available The title compound, [Cu(NCS2(C20H21N3]·0.5CH2Cl2, crystallized with two independent complex molecules (A and B in the asymmetric unit, accompanied by one dichloromethane solvent molecule. Each CuII atom has a square-pyramidal geometry, being coordinated by five N atoms, three from the (4-methylbenzylbis(pyridin-2-ylmethylamine ligand and two from the thiocyanate ligands. In the crystal, the B molecules are linked via C—H...S interactions, forming chains propagating along [100].

  1. 3-{[Bis(pyridin-2-ylmethylamino]methyl}-2-hydroxy-5-methylbenzaldehyde

    Directory of Open Access Journals (Sweden)

    Ruo-Xu Wang

    2012-06-01

    Full Text Available In the title compound, C21H21N3O2, the pyridine rings and the benzene ring lie in a propeller arrangement around the central tertiary amine N atom. The dihedral angles formed by the benzene ring with the pyridine rings are 61.0 (3 and 49.6 (3°, while the dihedral angle between the pyridine rings is 69.7 (3°. The molecular conformation is stabilized by intramolecular bifurcated O—H...N hydrogen bonds. In the crystal, inversion dimers are formed via pairs of C—H...N hydrogen bonds.

  2. Drug: D07563 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D07563 Drug Alizapride hydrochloride; Plitican (TN) C16H21N5O2. HCl 351.1462 351.83...ETABOLISM A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS A03F PROPULSIVES A03FA Propulsives A03FA05 Alizapride D07563 Alizapride...receptors Rhodopsin family Dopamine dopamine D2-receptor [HSA:1813] [KO:K04145] Alizapride... [ATC:A03FA05] D07563 Alizapride hydrochloride CAS: 59338-87-3 PubChem: 51091884 LigandBox: D07563

  3. 5′-Methyl-4′-oxo-7′-phenyl-3′,4′-dihydro-1′H-spiro[cyclohexane-1,2′-quinazoline]-8′-carbonitrile

    Directory of Open Access Journals (Sweden)

    Jianhong Tang

    2011-07-01

    Full Text Available The title compound, C21H21N3O, was obtained by cyclocondensation of 3-amino-5-methyl-[1,1′-biphenyl]-2,4-dicarbonitrile with cyclohexanone. The six-membered 1,3-diaza ring assumes an envelope conformation [with the flap atom displaced by 0.511 (7 Å from the plane through the other ring atoms] and the cyclohexane ring displays a chair conformation. The dihedral angle between the aromatic rings is 42.61 (7°.In the crystal, the molecules form hydrogen-bonded bands along [011].

  4. (E-N-[Cyclopentyl(morpholin-4-ylmethylidene]-4-fluorobenzenesulfonamide

    Directory of Open Access Journals (Sweden)

    Ilya Efimov

    2016-01-01

    Full Text Available The title compound, C16H21FN2O3S, was obtained from the reaction between sulfonyl azide, cyclohexanone and morpholine. The bond lengths at the amidine N—C—N grouping are similar [1.326 (3 and 1.338 (3 Å], indicating significant conjugation. The cyclopentyl moiety displays disorder of one of the methylene groups into two orientations with occupancy coefficients 0.75/0.25. No shortened intermolecular contacts in the crystal are observed.

  5. Crystal structure of 1-(2,4-dimethylphenyl-2-(4-trimethylsilyl-1H-1,2,3-triazol-1-ylethanone

    Directory of Open Access Journals (Sweden)

    G. B. Venkatesh

    2014-12-01

    Full Text Available The asymmetric unit of the title compound, C15H21N3OSi, contains two molecules with similar conformations (r.m.s. overlay fit for the 20 non-H atoms = 0.163 Å. The dihedral angles between the planes of the 1,2,3-triazole and 2,4-dimethylbenzene rings are 27.0 (3 and 19.5 (3°. In the crystal, molecules are linked by very weak C—H...O and C—H...N hydrogen bonds to generate [100] chains. The chains are cross-linked by C—H...π interactions.

  6. turboTDDFT 2.0 - Hybrid functionals and new algorithms within time-dependent density-functional perturbation theory

    CERN Document Server

    Ge, Xiaochuan; Rocca, Dario; Gebauer, Ralph; Baroni, Stefano

    2014-01-01

    We present a new release of the turboTDDFT code featuring an implementation of hybrid functionals, a recently introduced pseudo-Hermitian variant of the Liouville-Lanczos approach to time-dependent density-functional perturbation theory, and a newly developed Davidson-like algorithm to compute selected interior eigenvalues/vectors of the Liouvillian super-operator. Our implementation is thoroughly validated against benchmark calculations performed on the cyanin (C$_{21}$O$_{11}$H$_{21}$) molecule using the Gaussian09 and turboTDDFT 1.0 codes.

  7. N-(2-Allyl-4-ethoxy-2H-indazol-5-yl-4-methylbenzenesulfonamide

    Directory of Open Access Journals (Sweden)

    Hakima Chicha

    2014-05-01

    Full Text Available The indazole ring system of the title compound, C19H21N3O3S, is almost planar (r.m.s. deviation = 0.0192 Å and forms dihedral angles of 77.99 (15 and 83.9 (3° with the benzene ring and allyl group, respectively. In the crystal, centrosymmetrically related molecules are connected by pairs of N—H...O hydrogen bonds into dimers, which are further linked by C—H...O hydrogen bonds, forming columns parallel to the b axis.

  8. trans-Dichloridobis[tris(2-methoxyphenylphosphine]palladium(II

    Directory of Open Access Journals (Sweden)

    Charmaine van Blerk

    2009-11-01

    Full Text Available The structure of the title compound, [PdCl2(C21H21O3P2], shows a nearly square-planar geometry for the PdII atom within the Cl2Pd[P(PhOMe3]2 ligand set. The PdII atom sits on a centre of inversion and therefore the asymmetric unit contains one half-molecule, i.e. half of one PdII atom, one Cl atom and one tris(2-methoxyphenylphosphine ligand.

  9. (S-Methyl 2-benzamido-3-(3,4-dimethoxyphenylpropanoate

    Directory of Open Access Journals (Sweden)

    Tricia Naicker

    2012-01-01

    Full Text Available The dimethoxypbenzene ring in the title compound, C19H21NO5, is gauche to the amide group and anti to the ester group. The chirality was confirmed to be S from two-dimensional NMR spectroscopy. In the crystal, N—H...O and C—H...O hydrogen bonds and several short-contact interactions (2.07–3.45 Å create chains parallel to [110]. The phenyl ring is disordered over two orientations in a 0.54 (2:0.46 (2 ratio.

  10. Tris(4-methylphenylphosphine selenide

    Directory of Open Access Journals (Sweden)

    Alfred Muller

    2011-01-01

    Full Text Available In the title molecule, C21H21PSe or PSe(C7H73, the P atom has a distorted PSeC3 tetrahedral environment, formed by the Se atom [P=Se = 2.1119 (5 Å] and three aryl rings. Two short intramolecular C—H...Se contacts occur. In the crystal, weak intermolecular C—H...Se interactions link the molecules into zigzag double chains propagating in [100]. The previous report of this structure [Zhdanov et al. (1953. Dokl. Akad. Nauk SSSR (Russ. (Proc. Nat. Acad. Sci. USSR, 92, 983–985] contained no geometrical data.

  11. Tris(4-methylphenyl)phosphine selenide

    OpenAIRE

    Alfred Muller

    2011-01-01

    In the title molecule, C21H21PSe or PSe(C7H7)3, the P atom has a distorted PSeC3 tetrahedral environment, formed by the Se atom [P=Se = 2.1119 (5) Å] and three aryl rings. Two short intramolecular C—H...Se contacts occur. In the crystal, weak intermolecular C—H...Se interactions link the molecules into zigzag double chains propagating in [100]. The previous report of this structure [Zhdanov et al. (1953). Dokl. Akad. Nauk SSSR (Russ.) (Proc. Na...

  12. Drug: D00110 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D00110 Drug Cocaine (USP); Cocaine (TN) C17H21NO4 303.1471 303.3529 D00110.gif Eryt...:K04841] hsa04726(6532) Serotonergic synapse hsa04728(6323+6531) Dopaminergic synapse hsa05030(6531) Cocaine... Sodium channel blocking drugs map07234 Neurotransmitter transporter inhibitors map05030 Cocaine addiction A... N01 ANESTHETICS N01B ANESTHETICS, LOCAL N01BC Esters of benzoic acid N01BC01 Cocaine D00110 Cocaine (USP) R... RESPIRATORY SYSTEM R02 THROAT PREPARATIONS R02A THROAT PREPARATIONS R02AD Anesthetics, local R02AD03 Cocaine D00110 Cocai

  13. Diazido{(S-1-phenyl-N,N-bis[(2-pyridylmethyl]ethanamine}copper(II

    Directory of Open Access Journals (Sweden)

    Sankara Rao Rowthu

    2011-07-01

    Full Text Available In the title compound, [Cu(N32(C20H21N3], the CuII ion is coordinated by the three N atoms of the (S-1-phenyl-N,N-bis[(2-pyridylmethyl]ethanamine ligand and two N atoms from two azide anions, resulting in a distorted square-pyramidal environment. A weak intermolecular C—H...N hydrogen-bonding interaction between one pyridine group of the ligand and an azide N atom of an adjacent complex unit gives a one-dimensional chain structure parallel to the c axis.

  14. La misura della pressione fiscale in rapporto al prodotto interno lordo in luogo del prodotto interno netto:un capitolo dell'illusione fiscale

    Directory of Open Access Journals (Sweden)

    Francesco Forte

    2012-04-01

    Full Text Available The present paper calls attention on a major macroeconomic fiscal illusion: that arising fram the current official practice of expressing the main fiscal indicators and particularly tax burden as percentage of GDP rather than NDPF (Net Domestic Product at Factor Costs. This methodology causes a systematic undervaluation af the tax burden, by something between 25% (Sweden and Austria and 15% (Switzerland. Correctly measured, tax bur­den in most European countries is much abave 50% and in the Nordic coun­tries above 65% or close to it!  JEL Codes: H20, H21Keywords:

  15. rac-Dimethyl 2-(tert-butylamino-5-oxo-4,5-dihydropyrano[3,2-c]chromene-3,4-dicarboxylate

    Directory of Open Access Journals (Sweden)

    S. Antony Inglebert

    2011-11-01

    Full Text Available The title compound, C20H21NO7, is asymmetric with a chiral centre located in the pyran ring and crystallizes as a racemate. The molecular framework is somewhat bent; the coumarin moiety and the pyran ring are inclined by 7.85 (5°. The molecular structure is characterized by an intramolecular N—H...O hydrogen bond, which generates an S(6 ring motif, and the crystal packing is stabilized by intermolecular C—H...O hydrogen bonds. The 3-carboxylate O atom is involved in both of them, having a bifurcated character.

  16. Drug: D07473 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D07473 Drug Atomoxetine (INN); Tomoxetine C17H21NO 255.1623 255.3547 D07473.gif Ant...TROPICS N06BA Centrally acting sympathomimetics N06BA09 Atomoxetine D07473 Atomoxetine (INN) USP drug classi...ty Disorder Agents, Non- amphetamines Atomoxetine D07473 Atomoxetine (INN) Target-based classification of dr...ugs [BR:br08310] Transporters Solute carrier family SLC6 SLC6A2 (noradrenalin transporter) [HSA:6530] [KO:K05035] Atomoxetine... [ATC:N06BA09] D07473 Atomoxetine (INN) CAS: 83015-26-3 PubChem:

  17. Drug: D08421 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D08421 Drug Procainamide (INN) C13H21N3O 235.1685 235.3253 D08421.gif Antiarrhythmic... Same as: C07401 ATC code: C01BA02 Class I antiarrhythmic agent voltage-gated sodium channel (SCN1A) blocke...581] Transporter inhibition: SLC47A1 [HSA:55244] map07037 Antiarrhythmic drugs map07213 Dopamine receptor ag... CLASS I AND III C01BA Antiarrhythmics, class Ia C01BA02 Procainamide D08421 Procainamide (INN) USP drug cla...ssification [BR:br08302] Cardiovascular Agents Antiarrhythmics Procainamide D08421 Procainamide (INN) Target

  18. Drug: D00483 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available 6H21NO2. HCl 295.1339 295.8044 D00483.gif Anti-adrenergic [beta-receptor]; Cardiac depressant [anti-arrhythmic...] Therapeutic category: 2123 2149 ATC code: C07AA05 Class II antiarrhythmic agent beta1-adrenergic recepto...enomic biomarker: CYP2D6 [HSA:1565] CYP inhibition: CYP1A2 [HSA:1544] map07037 Antiarrhythmic drugs map07048... Cardiovascular agents 212 Antiarrhythmic agents 2123 Beta blockers D00483 Propranolol hydrochloride (JP16/U

  19. Drug: D00477 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available Pronestyl (TN) C13H21N3O. HCl 271.1451 271.7863 D00477.gif Cardiac depressant [anti-arrhythmic] Therapeutic ...category: 2121 ATC code: C01BA02 Class I antiarrhythmic agent (Ia) voltage-gated sodium channel (SCN1A) bloc...:6581] Transporter inhibition: SLC47A1 [HSA:55244] map07028 Antipsychotics map07037 Antiarrhythmic drugs map...TIARRHYTHMICS, CLASS I AND III C01BA Antiarrhythmics, class Ia C01BA02 Procainami...de D00477 Procainamide hydrochloride (JP16/USP) USP drug classification [BR:br08302] Cardiovascular Agents Antiarrhythmic

  20. Drug: D02100 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D02100 Drug Ziprasidone mesylate (USAN); Ziprasidone mesylate hydrate; Geodon (TN) ...C21H21ClN4OS. CH4SO3. 3H2O 562.1323 563.0871 D02100.gif Antipsychotic [central D2 and 5HT2 receptor antagoni... N05 PSYCHOLEPTICS N05A ANTIPSYCHOTICS N05AE Indole derivatives N05AE04 Ziprasidone D02100 Ziprasidone mesyl...ate (USAN) USP drug classification [BR:br08302] Antipsychotics 2nd Generation/Atypical Ziprasidone D02100 Zi...prasidone mesylate (USAN) Bipolar Agents Bipolar Agents, Other Ziprasidone D02100

  1. Drug: D01004 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D01004 Drug Homatropine hydrobromide (JP16/USP); Isopto homatropine (TN) C16H21NO3.... HBr 355.0783 356.2548 D01004.gif Anticholinergic [ophthalmic] Therapeutic category: 1311 ATC code: S01FA05 ...ing nervous system and sensory organs 13 Agents affecting sensory organs 131 Ophthalmic agents 1311 Mydriatic agents D0100... S01FA Anticholinergics S01FA05 Homatropine D01004 Homatropine hydrobromide (JP16/USP) Target-based classifi...nic cholinergic receptor [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133] Homatropine [ATC:S01FA05] D0100

  2. Aids to Navigation Service Force Mix 2000 Project. Volume 1. Development and Application of an Aids to Navigation Service Force Mix Decision Support System

    Science.gov (United States)

    1992-07-01

    Hours: 0.00 LT ANT ?: DBN ANT ?: (Database: Survey.db Report#: 6) Appendix H Page H-21 12/02/91 BUOY TENDER SUMMARY Page 22 Primary Unit: ACACIA District...2-5 2.2.4 ATON Tug Barges ........................ 2-5 2.2.5 Aids to Navigation Teams ( ANTs ) ................. 2-6 2.3 ATON SERVICES...navigation boat ANT aids to navigation team AOPS abstract of operations ATON aids to navigation ATONIS aids to navigation information system BRIDGE

  3. 5′-Methylsulfanyl-4′-oxo-7′-phenyl-3′,4′-dihydro-1′H-spiro[cyclohexane-1,2′-quinazoline]-8′-carbonitrile dimethylformamide monosolvate

    Directory of Open Access Journals (Sweden)

    Xuan Liu

    2011-08-01

    Full Text Available In the title compound, C21H21N3OS·C3H7NO, the carbonitrile molecule is built up of two fused six-membered rings and one six-membered ring linked through a spiro C atom. The 1,3-diaza ring adopts an envelope conformation and the cyclohexane ring adopts a chair conformation. The dihedral angle between the aromatic rings is 46.7 (3°. In the crystal, the components are linked by N—H...O hydrogen bonds.

  4. Drug: D02689 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D02689 Drug Ramelteon (JAN/USAN/INN); Rozerem (TN) C16H21NO2 259.1572 259.3434 D026...sory organs 11 Agents affecting central nervous system 119 Miscellaneous 1190 Miscellaneous D02689 Ramelteon... N NERVOUS SYSTEM N05 PSYCHOLEPTICS N05C HYPNOTICS AND SEDATIVES N05CH Melatonin receptor agonists N05CH02 Ramelteon D02689 Ramelt...eon (JAN/USAN/INN) USP drug classification [BR:br08302] Sleep Disorder Agents Sleep Disorders, Other Ramelt...eon D02689 Ramelteon (JAN/USAN/INN) Target-based classificat

  5. Drug: D03797 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D03797 Drug Prinomastat (USAN/INN) C18H21N3O5S2 423.0923 423.5064 D03797.gif Antine...metalloproteinase 2 [HSA:4313] [KO:K01398] Prinomastat D03797 Prinomastat (USAN/INN) matrix metalloproteinas...e 3 [HSA:4314] [KO:K01394] Prinomastat D03797 Prinomastat (USAN/INN) matrix metal...loproteinase 9 [HSA:4318] [KO:K01403] Prinomastat D03797 Prinomastat (USAN/INN) matrix metalloproteinase 13 ...[HSA:4322] [KO:K07994] Prinomastat D03797 Prinomastat (USAN/INN) matrix metalloproteinase 14 [HSA:4323] [KO:K07763] Prinomas

  6. Money or Joy

    DEFF Research Database (Denmark)

    Alstadsæter, Annette; Kolm, Anne-Sofie; Larsen, Birthe

    2005-01-01

    This paper examines the effect of taxes on the individuals' choices of educational direction, and thus on the economy.s skill composition. A proportional labour tax induces too many workers with high innate ability to choose an educational type associated with high consumption value and low effort....... This increases the skill mismatch and aggregate unemployment in the economy. The government can correct for this distortion by use of differentiated tuition fees or tax rates.JEL codes: J64, J68, H21, H24Keywords: Unemployment, matching, education, optimal taxation, tuition fees...

  7. Acoustooptic Diffraction in Borate Crystals

    CERN Document Server

    Martynyuk-Lototska, I; Krupych, O; Adamiv, V; Smirnov, Ye; Vlokh, R

    2004-01-01

    The efficiency of acoustooptic (AO) diffraction in a-BaB2O4 and Li2B4O7 crystals is studied experimentally. The crystals are shown to be quite good AO materials. The efficiency of AO diffraction in a-BaB2O4 reaches h=30% at the electric signal power of P=0.7W for the transverse acoustic wave and 15% at the power of P=0.56W for the longitudinal wave. The same parameter for Li2B4O7 reaches h=21% at P=0,81W for the longitudinal acoustic wave.

  8. Diphenyl[2-(2-pyridylaminomethylphenyl]phosphine oxide

    Directory of Open Access Journals (Sweden)

    Simón Hernández-Ortega

    2010-05-01

    Full Text Available The title compound, C24H21N2OP, was obtained by reacting 2-aminopyridine and 2-(diphenylphosphinylbenzaldehyde in ethanol. It crystallizes with two crystallographically independent molecules in the asymmetric unit. The aminopyridine units and the benzene ring bonded to the phosphine oxide P atom form dihedral angles of 88.58 (7 and 82.47 (9° in the two molecules. The crystal structure displays strong N—H...O and weak C—H...O hydrogen bonds along the b axis and C—H...π aromatic intra- and intermolecular interactions.

  9. ALMA Observations of Orion Source I at 350 and 660 GHz

    CERN Document Server

    Plambeck, R L

    2016-01-01

    Orion Source I ('SrcI') is the protostar at the center of the Kleinmann-Low Nebula. ALMA observations of SrcI at 350 and 660 GHz failed to detect the H26$\\alpha$ and H21$\\alpha$ recombination lines, ruling out the possibility that SrcI is a hypercompact HII region. The deconvolved size of the continuum source is approximately 0.23 x 0.05" (100 x 20 AU); it is interpreted as a disk viewed almost edge-on. The continuum flux density is proportional to $\

  10. Diethyl [(4-nitrobenzamido(phenylmethyl]phosphonate

    Directory of Open Access Journals (Sweden)

    Jing-Wei Chen

    2014-05-01

    Full Text Available In the title compound, C18H21N2O6P, the dihedral angle between the benzene and phenyl rings is 85.1 (2°. In the crystal, molecules are linked via pairs of N—H...O(=P hydrogen bonds, forming inversion dimers with graph-set notation R22(10. One of the ethyl groups is disordered over two sets of sites, with occupancies 0.746 (11 and 0.254 (11.

  11. Crystal structure of diethyl [(4-nitrophenylamino(2-hydroxyphenylmethyl]phosphonate methanol monosolvate

    Directory of Open Access Journals (Sweden)

    QingMing Wang

    2014-09-01

    Full Text Available In the title compound, C17H21N2O6P·CH3OH, the planes of the 4-nitroaniline and 2-hydroxyphenyl groups form a dihedral angle of 84.04 (8°. The P atom exhibits tetrahedral geometry involving two O-ethyl groups, a Cα atom and a double-bonded O atom. In the crystal, O—H...O, N—H...O and C—H...O hydrogen bonds link the α-aminophosphonic acid and methanol molecules into chains that propagate parallel to the a axis.

  12. Dichlorido[N-(N,N-dimethylcarbamimidoyl-N′,N′,4-trimethylbenzohydrazonamide]platinum(II nitromethane hemisolvate

    Directory of Open Access Journals (Sweden)

    Dmitrii S. Bolotin

    2014-04-01

    Full Text Available In the title compound, [PtCl2(C13H21N5]·0.5CH3NO2, the PtII atom is coordinated in a slightly distorted square-planar geometry by two Cl atoms and two N atoms of the bidentate ligand. The (1,3,5-triazapentadienePtII metalla ring is slightly bent and does not conjugate with the aromatic ring. In the crystal, N—H...Cl hydrogen bonds link the complex molecules, forming chains along [001]. The nitromethane solvent molecule shows half-occupancy and is disordered over two sets of sites about an inversion centre.

  13. Calculation of Electromagnetic Scattering by a Perfect Conductor.

    Science.gov (United States)

    1980-06-05

    AD-A091 027 NAVAL SURFACE WEAPONS CENTER SILVER SPRING NO0 F/G 20/3 CALCULATION OF ELECTROMAGNETIC SCATTERING BY A PERFECT CONDUCTO --ETCIU) JUN G0 A...let aO,r nonBr. We have 1E.2 - aHl.2 = V.(H I x E2) BE 1.E 2 _ * H H_ . 21. MUller , C., Foundations of the Mathematical Theory of Electromagnetic...20. Kellogg, R. B., "A Scattering Problem for Maxwell’s Equations," Ibid. 21. MUller , C., Foundations of the Mathematical Theory of Electromagnetic

  14. 3-(4-Hexyloxyphenyl-1,2,4-triazolo[3,4-b]benzothiazole

    Directory of Open Access Journals (Sweden)

    Dieter Schollmeyer

    2014-03-01

    Full Text Available The title compound, C20H21N3OS, was prepared by Huisgen reaction of 5-(4-hexyloxyphenyltetrazole and chlorobenzothiazole. The essentially planar benzothiazolotriazole framework [maximum deviation from the mean plane of 0.077 (1 Å for the bridgehead N atom] and the phenyl ring form a dihedral angle of 53.34 (5°. The hexyloxy chain adopts a gauche–all-anti conformation. The intracentroid separation of 3.7258 (8 Å between the triazole and benzene rings is the closest contact between individual molecules in the crystal.

  15. Ethyl 2-(4-bromophenyl-1-[3-(1H-imidazol-1-ylpropyl]-1H-benzimidazole-5-carboxylate monohydrate

    Directory of Open Access Journals (Sweden)

    Yeong Keng Yoon

    2011-11-01

    Full Text Available In the title compound, C22H21BrN4O2·H2O, the two pyrazole rings are essentially planar [maximum deviations 0.002 (1 and 0.002 (1 Å], and form a dihedral angle of 73.46 (9°. The dihedral angle between the benzene rings is 29.33 (7°. In the crystal, molecules are connected via C—H...O and O—H...N hydrogen bonds, forming layers in the ab plane.

  16. 1-[(6-Chloro-3-pyridylmethyl]-N-(4-ethoxyphenyl-3-phenyl-1H-pyrazole-5-carboxamide

    Directory of Open Access Journals (Sweden)

    Zheng Tang

    2009-04-01

    Full Text Available In the title compound, C24H21ClN4O2, the pyrazole ring makes dihedral angles of 7.70 (11, 89.17 (11 and 40.68 (11° with the phenyl, pyridine and ethoxyphenyl rings, respectively. There are some intramolecular C—H...O and C—H...π bonds giving rigidity to the molecule, while weak intermolecular N—H...N and C—H...π hydrogen bonds link the molecules into a two-dimensional structure.

  17. Crystal structure of 5-[4-(di-methyl-amino)-phen-yl]-3-(4-methyl-phen-yl)-4,5-di-hydro-1H-pyrazole-1-carbaldehyde.

    Science.gov (United States)

    Adam, Farook; Samshuddin, Seranthimata; Ameram, Nadiah; Subramaya; Samartha, Laxminarayana

    2015-12-01

    The title compound, C19H21N3O, comprises a central pyrazole ring which is N-connected to an aldehyde group and C-connected twice to substituted benzene rings. The pyrazole ring is twisted on the C-C single bond, and the least-squares plane through this ring forms dihedral angles of 82.44 (5) and 4.52 (5)° with the (di-methyl-amino)-benzene and p-tolyl rings, respectively. In the crystal, weak C-H⋯O hydrogen bonds link mol-ecules into supra-molecular tubes along the b axis.

  18. Drug: D08100 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D08100 Drug Ketobemidone (INN) C15H21NO2 247.1572 247.3327 D08100.gif Opioid Analge... NERVOUS SYSTEM N02 ANALGESICS N02A OPIOIDS N02AB Phenylpiperidine derivatives N02AB01 Ketobemidone D08100 K...04 2905 2906] [KO:K05208 K05209 K05210 K05211 K05212] Ketobemidone [ATC:N02AB01] D08100 Ketobemidone (INN) C...AS: 469-79-4 PubChem: 96024790 LigandBox: D08100 NIKKAJI: J5.929C ATOM 18 1 C1z C

  19. Development of The Viking Speech Scale to classify the speech of children with cerebral palsy.

    Science.gov (United States)

    Pennington, Lindsay; Virella, Daniel; Mjøen, Tone; da Graça Andrada, Maria; Murray, Janice; Colver, Allan; Himmelmann, Kate; Rackauskaite, Gija; Greitane, Andra; Prasauskiene, Audrone; Andersen, Guro; de la Cruz, Javier

    2013-10-01

    Surveillance registers monitor the prevalence of cerebral palsy and the severity of resulting impairments across time and place. The motor disorders of cerebral palsy can affect children's speech production and limit their intelligibility. We describe the development of a scale to classify children's speech performance for use in cerebral palsy surveillance registers, and its reliability across raters and across time. Speech and language therapists, other healthcare professionals and parents classified the speech of 139 children with cerebral palsy (85 boys, 54 girls; mean age 6.03 years, SD 1.09) from observation and previous knowledge of the children. Another group of health professionals rated children's speech from information in their medical notes. With the exception of parents, raters reclassified children's speech at least four weeks after their initial classification. Raters were asked to rate how easy the scale was to use and how well the scale described the child's speech production using Likert scales. Inter-rater reliability was moderate to substantial (k>.58 for all comparisons). Test-retest reliability was substantial to almost perfect for all groups (k>.68). Over 74% of raters found the scale easy or very easy to use; 66% of parents and over 70% of health care professionals judged the scale to describe children's speech well or very well. We conclude that the Viking Speech Scale is a reliable tool to describe the speech performance of children with cerebral palsy, which can be applied through direct observation of children or through case note review.

  20. Electrochemical Behavior and Determination of Trifluoperazine at Decanethiol Self- Assembled Monolayer Modified Gold Electrodes

    Institute of Scientific and Technical Information of China (English)

    HUANG Fei; YAN Quan-ping; ZENG Bai-zhao

    2005-01-01

    The electrochemical behavior of trifluoperazine at decanethiol self-assembled monolayer (SAM) modified gold electrodes (i. e. C10 H21 SH/Au) has been studied. Trifluoperazine can effectively accumulate on C10 H21 SH/Au elec trodes and generate a sensitive anodic peak at about 0. 63 V (vs. SCE) in 0.05 mol/L pH 9.4 Na2B4O7 buffer solution.Under the selected conditions, the anodic peak current was linear to trifluoperazine concentration in the range of 5.0 ×10 7-3. 0× 10-5 mol/L with correlation coefficient of 0. 997,the detection limit was 3.0 × 10-8 mol/L. This method was applied to the determination of trifluoperazine in drug samples and the recovery was 97.3%-104.0%. It was found that sodium dodecyl sulfate (SDS) could make the anodic peak current increase. In the presence of SDS, the peak at about 0.63V turned into two peaks, resulting from the change of the electrochemical mechanism.

  1. Comparison of eight different agars for the recovery of clinically relevant non-O157 Shiga toxin-producing Escherichia coli from baby spinach, cilantro, alfalfa sprouts and raw milk.

    Science.gov (United States)

    Kase, Julie A; Maounounen-Laasri, Anna; Son, Insook; Lin, Andrew; Hammack, Thomas S

    2015-04-01

    The FDA Bacteriological Analytical Manual (BAM) Chapter 4a recommends several agars for isolating non-O157 Shiga toxin-producing Escherichia coli (STEC); not all have been thoroughly tested for recovering STECs from food. Using E. coli strains representing ten clinically relevant O serogroups (O26, O45, O91, O103, O104, O111, O113, O121, O128, O145) in artificially-contaminated fresh produce--bagged baby spinach, alfalfa sprouts, cilantro, and raw milk--we evaluated the performance of 8 different agars. Performance was highly dependent upon strain used and the presence of inhibitors, but not necessarily dependent on food matrix. Tellurite resistant-negative strains, O91:-, O103:H6, O104:H21, O113:H21, and O128, grew poorly on CHROMagar STEC, Rainbow agar O157, and a modified Rainbow O157 (mRB) agar. Although adding washed sheep's blood to CHROMagar STEC and mRB agars improved overall performance; however, this also reversed the inhibition of non-target bacteria provided by original formulations. Variable colony coloration made selecting colonies from Rainbow agar O157 and mRB agars difficult. Study results support a strategy using inclusive agars (e.g. L-EMB, SHIBAM) in combination with selective agars (R & F E. coli O157:H7, CHROMagar STEC) to allow for recovery of the most STECs while increasing the probability of recovering STEC in high bacterial count matrices.

  2. The occurrence of subtilase-cytotoxin-encoding genes in environmental Escherichia coli isolated from a Northern California estuary.

    Science.gov (United States)

    Pereira, Maria das Graças C; Byrne, Barbara A; Nguyen, Trân B H; Lewis, David J; Atwill, E Robert

    2013-06-01

    The presence of subtilase-cytotoxin-encoding genes was determined in 397 environmental Escherichia coli strains isolated from water, suspended solids, and sediments sampled from different hydrological and environmental conditions in a California estuary. A total of 7 strains (1.76%) were found to harbor subtilase-cytotoxin-encoding genes. Using primers targeting subA only, we generated PCR amplicons from 2 strains; while using primers targeting the 3' end of SubA downstream to the 5' end of SubB, amplicons of 232 bp were generated from 5 additional strains. The 556 bp subA sequences were almost identical to that in the subtilase-cytotoxin-positive strain ED 591 (98%), while subAB sequences of 2 non-Shiga-toxigenic strains revealed 100% similarity with the Shiga-toxigenic E. coli O113:H21 strain 98NK2 that was isolated from an outbreak of hemolytic uremic syndrome. Additionally, the serogroup O113:H21 was present in this collection of environmental E. coli, and it was found to harbor stx2d, hra1 that encodes the heat resistant agglutinin 1, and a subAB sequence similar to that in the non-Shiga-toxigenic E. coli subtilase cytotoxin strain ED 591. To further understand potential health risks posed by strains encoding SubAB, future epidemiological studies should consider screening isolates for subAB regardless of the presence of Shiga-toxin-encoding genes.

  3. Size distribution of particle-phase molecular markers during a severe winter pollution episode.

    Science.gov (United States)

    Kleeman, Michael J; Riddle, Sarah G; Jakober, Chris A

    2008-09-01

    Airborne particulate matter was collected using filter samplers and cascade impactors in six size fractions below 1.8 microm during a severe winter air pollution event at three sites in the Central Valley of California. The smallest size fraction analyzed was 0.056 source apportionment calculations. Colocated impactor and filter measurements were highly correlated (R8 > 0.8) for retene, benzo[ghi]flouranthene, chrysene, benzo[b]fluoranthene, benzo[k]fluoranthene, benzo[e]pyrene, benzo[a]pyrene, perylene, indeno[1,2,3-cd]pyrene, benzo[ghi]perylene, coronene, MW302 polycyclic aromatic hydrocarbon (PAHs), 17beta(H)-21alpha(H)-30-norhopane, 17alpha(H)-21beta(H)-hopane, alphabetabeta-20R-C29-ethylcholestane, levoglucosan, and cholesterol. Of these compounds, levoglucosan was present in the highest concentration (60-2080 ng m(-3)) followed by cholesterol (6-35 ng m(-3)), PAHs (2-38 ng m(-3)), and hopanes and steranes (0-2 ng m(-3)). Nighttime concentrations were higher than daytime concentrations in all cases. Organic compound size distributions were generally similar to the total carbon size distributions during the nighttime but showed greater variability during the daytime. This may reflect the dominance of fresh emission in the stagnant surface layer during the evening hours and the presence of aged organic aerosol at the surface during the daytime when the atmosphere is better mixed. All of the measured organic compound particle size distributions had a single mode that peaked somewhere between 0.18 and 0.56 microm, but the width of each distribution varied by compound. Cholesterol generally had the broadest particle size distribution, while benzo[ghi]perylene and 17alpha(H)-21beta(H)-29-norhopane generally had sharper peaks. The difference between the size distributions of the various particle-phase organic compounds reflects the fact that these compounds exist in particles emitted from different sources. The results of the current study will prove useful for size

  4. 2010年福建南平及永安监测点致泻大肠杆菌的监测报告%Surveillance of diarrheagenic Escherichia coli infection in Nanping and Yongan monitoring sites of Fujian in 2010

    Institute of Scientific and Technical Information of China (English)

    林杰; 陈爱平; 陈建辉; 李玉燕; 杨劲松; 郑金凤

    2011-01-01

    目的:为了解福建省腹泻病人中致泻大肠杆菌的感染情况.方法:应用多重PCR或单重PCR方法检测致泻大肠杆菌的EPEC/EHEC eaeA基因、EHEC stx基因、EAEC aggR基因、EIECipaH、EIEC virA、ETEC ST、ETEC LT、EPECbp基因.API 20E生化鉴定条进行生化试验.血清学鉴定.结果:2010年度共分离得19株致泻大肠杆菌,检出率为10.9%.1株EAEC;1株tEPEC;4株aEPEC; 13株ETEC.19株分离的致泻大肠杆菌经API 20E鉴定均为大肠埃希菌.1株tEPEC与EPEC三种多价诊断血清型均不凝集,而1株aEPEC血清型为O111:K58(B4).13株ETEC菌株血清型:多数为O6:K15,1株O25:K19(L),3株未能分型.结论:监测结果对于我们了解福建省致泻大肠杆菌感染情况,预警潜在发生疫情的可能性有其重要性.这些菌种的获得可以为下一步研究其毒力特征、分子分型及耐药性积累原始材料.%Objective:To understand the condition of Diarrheagenic Escherichia coli (DEC) infection in Fujian province. Methods: Genes such as EPEC/EHEC eaek, EHEC stx, EAEC aggR, EIEC ipaH, EIEC virA, ETEC ST, ETEC LT, EPEC bfp were detected by multiplex or single PCR. Biochemical identification was determined by API 20E strip and serotyping was performed. Results: 19 strains of DEC (1 EAEC, 1 tEPEC, 4 aEPEC and 13 ETEC) were isolated in the surveillance in 2010, and the detection rate was 10.9%. All isolated strains were identified as E. Coli by API 20E strip. 1 tEPEC didn't agglutinate with EPEC multivalence diagnostic serum, whereas 1 aEPEC agglutinated with EPEC serum 0111 :K58( B4). Serotypes of 13 ETEC were mainly 06:K15, while the others were 1 strain for O25:K19(L) , 3 strains untyped. Conclusion: The surveillance is important to understand DEC infection in Fujian province and early warn the potential of DEC epidemic. The isolated strains provide material for further study of their virulence characteristics, molecular typing and antibiotic resistance.

  5. A shock tube and theoretical study on the pyrolysis of 1,4-dioxane.

    Science.gov (United States)

    Yang, X; Jasper, A W; Giri, B R; Kiefer, J H; Tranter, R S

    2011-03-07

    The dissociation of 1, 2 and 4% 1,4-dioxane dilute in krypton was studied in a shock tube using laser schlieren densitometry, LS, for 1550-2100 K with 56 ± 4 and 123 ± 3 Torr. Products were identified by time-of-flight mass spectrometry, TOF-MS. 1,4-dioxane was found to initially dissociate via C-O bond fission followed by nearly equal contributions from pathways involving 2,6 H-atom transfers to either the O or C atom at the scission site. The 'linear' species thus formed (ethylene glycol vinyl ether and 2-ethoxyacetaldehyde) then dissociate by central fission at rates too fast to resolve. The radicals produced in this fission break down further to generate H, CH(3) and OH, driving a chain decomposition and subsequent exothermic recombination. High-level ab initio calculations were used to develop a potential energy surface for the dissociation. These results were incorporated into an 83 reaction mechanism used to simulate the LS profiles with excellent agreement. Simulations of the TOF-MS experiments were also performed with good agreement for consumption of 1,4-dioxane. Rate coefficients for the overall initial dissociation yielded k(123Torr) = (1.58 ± 0.50) × 10(59) × T(-13.63) × exp(-43970/T) s(-1) and k(58Torr) = (3.16 ± 1.10) × 10(79) × T(-19.13) × exp(-51326/T) s(-1) for 1600 < T < 2100 K.

  6. Budgeting of major nutrients and the mitigation options for nutrient mining in semi-arid tropical agro-ecosystem of Tamil Nadu, India using NUTMON model.

    Science.gov (United States)

    Surendran, U; Rama Subramoniam, S; Raja, P; Kumar, V; Murugappan, V

    2016-04-01

    Mining of nutrients from soil is a major problem in developing countries causing soil degradation and threaten long-term food production. The present study attempts to apply NUTrient MONitoring (NUTMON) model for carrying out nutrient budgeting to assess the stocks and flows of nitrogen (N), phosphorus (P), and potassium (K) in defined geographical unit based on the inputs, viz., mineral fertilizers, manures, atmospheric deposition, and sedimentation, and outputs, viz., harvested crop produces, residues, leaching, denitrification, and erosion losses. The study area covers Coimbatore and Erode Districts, which are potential agricultural areas in western agro-ecological zone of Tamil Nadu, India. The calculated nutrient balances for both the districts at district scale, using NUTMON methodology, were negative for nitrogen (N -3.3 and -10.1 kg ha(-1)) and potassium (K -58.6 and -9.8 kg ha(-1)) and positive for phosphorus (P +14.5 and 20.5 kg ha(-1)). Soil nutrient pool has to adjust the negative balance of N and K; there will be an expected mining of nutrient from the soil reserve. A strategy was attempted for deriving the fertilizer recommendation using Decision Support System for Integrated Fertilizer Recommendation (DSSIFER) to offset the mining in selected farms. The results showed that when DSSIFER recommended fertilizers are applied to crops, the nutrient balance was positive. NUTMON-Toolbox with DSSIFER would serve the purpose on enhancing soil fertility, productivity, and sustainability. The management options to mitigate nutrient mining with an integrated system approach are also discussed.

  7. Molecular and Genetic Characterization of HIV-1 Tat Exon-1 Gene from Cameroon Shows Conserved Tat HLA-Binding Epitopes: Functional Implications

    Science.gov (United States)

    Teto, Georges; Fonsah, Julius Y.; Tagny, Claude T.; Mbanya, Dora; Nchindap, Emilienne; Kenmogne, Leopoldine; Fokam, Joseph; Njamnshi, Dora M.; Kouanfack, Charles; Njamnshi, Alfred K.; Kanmogne, Georgette D.

    2016-01-01

    HIV-1 Tat plays a critical role in viral transactivation. Subtype-B Tat has potential use as a therapeutic vaccine. However, viral genetic diversity and population genetics would significantly impact the efficacy of such a vaccine. Over 70% of the 37-million HIV-infected individuals are in sub-Saharan Africa (SSA) and harbor non-subtype-B HIV-1. Using specimens from 100 HIV-infected Cameroonians, we analyzed the sequences of HIV-1 Tat exon-1, its functional domains, post-translational modifications (PTMs), and human leukocyte antigens (HLA)-binding epitopes. Molecular phylogeny revealed a high genetic diversity with nine subtypes, CRF22_01A1/CRF01_AE, and negative selection in all subtypes. Amino acid mutations in Tat functional domains included N24K (44%), N29K (58%), and N40K (30%) in CRF02_AG, and N24K in all G subtypes. Motifs and phosphorylation analyses showed conserved amidation, N-myristoylation, casein kinase-2 (CK2), serine and threonine phosphorylation sites. Analysis of HLA allelic frequencies showed that epitopes for HLAs A*0205, B*5301, Cw*0401, Cw*0602, and Cw*0702 were conserved in 58%–100% of samples, with B*5301 epitopes having binding affinity scores > 100 in all subtypes. This is the first report of N-myristoylation, amidation, and CK2 sites in Tat; these PTMs and mutations could affect Tat function. HLA epitopes identified could be useful for designing Tat-based vaccines for highly diverse HIV-1 populations, as in SSA. PMID:27438849

  8. Molten salt CO2 capture and electro-transformation (MSCC-ET) into capacitive carbon at medium temperature: effect of the electrolyte composition.

    Science.gov (United States)

    Deng, Bowen; Chen, Zhigang; Gao, Muxing; Song, Yuqiao; Zheng, Kaiyuan; Tang, Juanjuan; Xiao, Wei; Mao, Xuhui; Wang, Dihua

    2016-08-15

    Electrochemical transformation of CO2 into functional materials or fuels (i.e., carbon, CO) in high temperature molten salts has been demonstrated as a promising way of carbon capture, utilisation and storage (CCUS) in recent years. In a view of continuous operation, the electrolysis process should match very well with the CO2 absorption kinetics. At the same time, in consideration of the energy efficiency, a molten salt electrochemical cell running at lower temperature is more beneficial to a process powered by the fluctuating renewable electricity from solar/wind farms. Ternary carbonates (Li : Na : K = 43.5 : 31.5 : 25.0) and binary chlorides (Li : K = 58.5 : 41.5), two typical kinds of eutectic melt with low melting points and a wide electrochemical potential window, could be the ideal supporting electrolyte for the molten salt CO2 capture and electro-transformation (MSCC-ET) process. In this work, the CO2 absorption behaviour in Li2O/CaO containing carbonates and chlorides were investigated on a home-made gas absorption testing system. The electrode processes as well as the morphology and properties of carbon obtained in different salts are compared to each other. It was found that the composition of molten salts significantly affects the absorption of CO2, electrode processes and performance of the product. Furthermore, the relationship between the absorption and electro-transformation kinetics are discussed based on the findings.

  9. Novel methanol-tolerant Ir-S/C chalcogenide electrocatalysts for oxygen reduction in DMFC fuel cell

    Institute of Scientific and Technical Information of China (English)

    Jingyu Ma; Desheng Ai; Xiaofeng Xie; Jianwei Guo

    2011-01-01

    Novel methanol-tolerant oxygen-reduction catalysts, iridium-sulphur (Ir-S) chalcogenides with differ ent Ir/S atomic ratios, were synthesized via a precipitation method using H21rCI6 and Na2SO3 as the Ir and S precursors. Powder X-ray diffraction (XRD) and transmission electron microscopy (TEM) were used to characterize the IrxSl-x/C chalcogenide catalysts. Particle size ranging from 2.5 to 2.8 nm though obvious agglomeration was found on carbon support. However, these chalcogenide catalysts showed strong catalytic activity towards the oxygen reduction reaction (ORR) and high methanol tolerance, strongly suggesting these novel catalysts as promising candidates for direct methanol fuel cell (DMFC) cathode applications.

  10. N-(3-{[(Z-(3-Hydroxy-4-methylphenylimino]methyl}pyridin-2-ylpivalamide

    Directory of Open Access Journals (Sweden)

    Şehriman Atalay

    2016-03-01

    Full Text Available The molecular structure of the title compound, C18H21N3O2, contains pivalamide, pyridin and hydroxy-methylphenyl moieties. The whole molecule is not planar, the dihedral angle between the benzene rings being 34.84 (7°. The molecular conformation is stabilized by an intramolecular N—H...N hydrogen bond. In the crystal, molecules are linked by O—H...O, O—H...N and C—H...O hydrogen bonds. The C and H atoms of the tert-butyl group disordered over two sets of sites with an occupancy ratio of 0.692 (5:0.308 (5.

  11. 5-Cyclohexyl-2-(2-fluorophenyl-3-methylsulfinyl-1-benzofuran

    Directory of Open Access Journals (Sweden)

    Hong Dae Choi

    2013-06-01

    Full Text Available In the title compound, C21H21FO2S, the cyclohexyl ring adopts a chair conformation. The 2-fluorobenzene ring makes a dihedral angle of 38.68 (6° with the mean plane [r.m.s. deviation = 0.018 (2 Å] of the benzofuran fragment. In the crystal, molecules are linked by pairs of C—H...O hydrogen bonds into dimers, which are further packed into stacks along the c axis by C—H...O hydrogen bonds. In addition, the stacked molecules exhibit S...O contacts [3.1733 (13 Å] involving the sulfinyl groups. The F atom is disordered over two positions, with site-occupancy factors of 0.961 (3 and 0.039 (3.

  12. 6-Butyl-5-(4-methylphenoxy-3-phenyl-3H-1,2,3-triazolo[4,5-d]pyrimidin-7(6H-one

    Directory of Open Access Journals (Sweden)

    Hong-Mei Wang

    2010-11-01

    Full Text Available In the title compound, C21H21N5O2, the triazolopyrimidine ring system is essentially planar [maximum displacement = 0.021 (4 Å] and forms dihedral angles of 41.17 (9 and 67.99 (8° with the phenyl and benzene rings, respectively. The n-butyl side chains is disordered over two positions with an ccupancy ratio of 0.77:0.23. An intramolecular C—H...O hydrogen-bonding interaction stabilizes the molecular conformation. In the crystal, molecules are linked by intermolecular C—H...O and C—H...N hydrogen bonds into a three-dimensional network. In addition, π–π stacking interactions involving the triazole and pyrimidine rings of adjacent molecules are observed, with centroid–centroid distances of 3.545 (1 Å.

  13. Bis[μ-N-(tert-butyldimethylsilylquinolin-8-aminato-1:2κ2N1,N8:N8](N,N,N′,N′-tetramethylethane-1,2-diamine-1κ2N,N′lithiumsodium

    Directory of Open Access Journals (Sweden)

    Juan Chen

    2012-12-01

    Full Text Available In the heterometallic title bulky amido complex, [LiNa(C15H21N2Si2(C6H16N2], both alkali metal ions are four-coordinated with distorted tetrahedral geometries. The Li+ ion is N,N′-chelated by the N-silylated amido ligand, with Li—N = 2.015 (5 and 2.074 (5 Å. The two amido ligands are arranged cis to each other. The molecule exhibits a twofold rotational symmetry operation along the Li–Na axis. The Na+ ion is coordinated by two N atoms from the tetramethylethylenediamine ligand [Na—N = 2.553 (4 Å] and shares two amido N atoms from the N-silylated amido ligands with the Li+ ion. Although the crystal structure contains voids with an approximate volume of 50 Å3 there is no inclusion of solvent molecules.

  14. Tetrahydroberberine, a pharmacologically active naturally occurring alkaloid.

    Science.gov (United States)

    Pingali, Subramanya; Donahue, James P; Payton-Stewart, Florastina

    2015-04-01

    Tetrahydroberberine (systematic name: 9,10-dimethoxy-5,8,13,13a-tetrahydro-6H-benzo[g][1,3]benzodioxolo[5,6-a]quinolizine), C20H21NO4, a widely distributed naturally occurring alkaloid, has been crystallized as a racemic mixture about an inversion center. A bent conformation of the molecule is observed, with an angle of 24.72 (5)° between the arene rings at the two ends of the reduced quinolizinium core. The intermolecular hydrogen bonds that play an apparent role in crystal packing are 1,3-benzodioxole -CH2···OCH3 and -OCH3···OCH3 interactions between neighboring molecules.

  15. Must losing taxes on saving be harmful?

    DEFF Research Database (Denmark)

    Huizinga, Harry; Nielsen, Søren Bo

    2004-01-01

    are financed by taxes on savingand investment. There is international cross-ownership of firms, and countries areassumed to be unable to tax away pure profits. Countries then face an incentiveto impose a rather high investment tax also borne by foreigners. In this setting,the loss of the saving tax instrument...... on account of international tax evasion mayprevent the overall saving-investment tax wedge from becoming too high, and hencemay be beneficial for moderate preferences for public goods. A world with 'high-spending' governments, in contrast, is made worse off by the loss of saving taxes,and hence stands...... to gain from international cooperation to restore saving taxation.JEL-Classifcation: H87, H21Keywords: Capital income taxation, cross-ownership, coordination...

  16. dc and microwave performance of a 0.1-micron gate InAs/In(0.52)Al(0.48)As MODFET

    Science.gov (United States)

    Yang, D.; Chen, Y. C.; Brock, T.; Bhattacharya, Pallab K.

    1992-06-01

    The performance characteristics of 0.1-micron gate InAs/In(0.52)Al(0.48)As MODFETs grown by molecular beam epitaxy are measured and analyzed. The transistors are characterized by measured g sub m (max) = 840 mS/mm, f sub T = 128 GHz, and a very high current carrying capability, e.g., I sub dss = 934 mA/mm at V sub gs = 0.4 V and V sub ds = 2.7 V. The value of f sub T is estimated from extrapolation of the current gain (H21) at a -6-dB/octave rolloff. This is the first report on the microwave characteristics of an InAs-channel MODFET and establishes the superiority of this heterostructure system.

  17. Bis{4-methylbenzyl 2-[4-(propan-2-ylbenzylidene]hydrazinecarbodithioato-κ2N2,S}nickel(II: crystal structure and Hirshfeld surface analysis

    Directory of Open Access Journals (Sweden)

    Enis Nadia Md Yusof

    2017-03-01

    Full Text Available The complete molecule of the title hydrazine carbodithioate complex, [Ni(C19H21N2S22], is generated by the application of a centre of inversion. The NiII atom is N,S-chelated by two hydrazinecarbodithioate ligands, which provide a trans-N2S2 donor set that defines a distorted square-planar geometry. The conformation of the five-membered chelate ring is an envelope with the NiII atom being the flap atom. In the crystal, p-tolyl-C—H...π(benzene-iPr, iPr-C—H...π(p-tolyl and π–π interactions [between p-tolyl rings with inter-centroid distance = 3.8051 (12 Å] help to consolidate the three-dimensional architecture. The analysis of the Hirshfeld surface confirms the importance of H-atom contacts in establishing the packing.

  18. A triclinic polymorph of (-)-(S)-N-benzyl-2-[(R)-6-fluoro-chroman-2-yl]-2-hy-droxy-ethanaminium bromide.

    Science.gov (United States)

    Rousselin, Yoann; Laureano, Hugo; Clavel, Alexandre

    2013-12-01

    The title salt, C18H21FNO2 (+)·Br(-), determined at 115 K, crystallizes in the triclinic space group P1. The previously reported polymorph occurs in the monoclinic space group P21 and has two independent mol-ecules in the asymmetric unit [Peeters et al. (1993 ▶). Acta Cryst. C49, 2157-2160]. In the title molecule, the pyran rings adopt half-chair conformations. The absolute configuration is S for the hy-droxy-bearing C atom and R for the asymmetric C atom in the di-hydro-pyran unit. In the crystal, the components are linked by N-H⋯Br and O-H⋯Br hydrogen bonds, forming chains along the c-axis direction. The crystal studied was refined as an inversion twin.

  19. Ethyl 2-(1,2,3,4-tetrahydro­spiro­[carba­zole-3,2′-[1,3]dioxolan]-9-yl)acetate

    Science.gov (United States)

    Löffler, Philipp M. G.; Ulven, Trond; Bond, Andrew D.

    2009-01-01

    In the title compound, C18H21NO4, the hydrogenated six-membered ring of the carbazole unit adopts a half-chair conformation. The dioxolane ring and ethyl­acetate substituent point to opposite sides of the carbazole plane. The ethyl­acetate substituent adopts an essentially fully extended conformation, and its mean plane forms a dihedral angle of 83.8 (1)° with respect to the carbazole mean plane. The mol­ecules are arranged into stacks in which the carbazole planes form a dihedral angle of 4.4 (1)° and have an approximate inter­planar separation of 3.6 Å. PMID:21582427

  20. Bis[(2-methylbenzylbis(pyridin-2-ylmethyl-κNamine-κN]manganese(II bis(perchlorate

    Directory of Open Access Journals (Sweden)

    Ray J. Butcher

    2014-03-01

    Full Text Available In the title complex, [Mn(C20H21N32](ClO42, two tridentate (2-methylbenzylbis(pyridin-2-ylmethylamine (L ligands form the MnII complex [MnL2](ClO42. The MnII ion lies on a twofold axis and the complex cation is significantly distorted from regular octahedral geometry. The packing is stabilized by weak C—H...O interactions between the cations and anions, which link them into a zigzag ribbon along [101]. The perchlorate anion is disordered and was constrained to be tetrahedral with two orientations having occupancies of 0.768 (4 and 0.232 (4. The 2-methylbenzyl moiety is also disordered over two sets of sites, with occupancies of 0.508 (15 and 0.492 (15.

  1. Chlorido[1-diphenylphosphanyl-3-(phenylsulfanylpropane-κ2P,S](η5-pentamethylcyclopentadienyliridium(III chloride monohydrate

    Directory of Open Access Journals (Sweden)

    Gerd Ludwig

    2012-06-01

    Full Text Available The crystal structure of the title compound, [Ir(C10H15Cl(C21H21PS]Cl·H2O, consists of discrete [Ir(η5-C5Me5Cl{Ph2P(CH23SPh-κP,κS}]+ cations, chloride anions and water molecules. The IrIII atom is coordinated by an η5-C5Me5 ligand, a chloride and a Ph2P(CH23SPh-κP,κS ligand, leading to a three-legged piano-stool geometry. In the crystal, two water molecules and two chloride anions are linked by weak O—H...Cl hydrogen bonding into tetramers that are located on centers of inversion. The H atoms of one of the methyl groups are disordered and were refined using a split model.

  2. Crystal structure of ethyl 2-(2,4,5-trimethoxyphenylquinoline-4-carboxylate

    Directory of Open Access Journals (Sweden)

    T. O. Shrungesh Kumar

    2015-07-01

    Full Text Available In the title compound, C21H21NO5, the dihedral angle between the quinoline ring system (r.m.s. deviation = 0.028 Å and the trimethoxybenzene ring is 43.38 (5°. The C atoms of the methoxy groups deviate from their attached benzene ring by −0.396 (2, −0.049 (2 and 0.192 (2 Å for the ortho-, meta- and para-substituents, respectively. The pendant ethyl chain is disordered over two orientations in a 0.527 (5:0.473 (5 ratio. A short intramolecular C—H...O contact closes an S(6 ring. In the crystal, inversion dimers linked by pairs of weak C—H...O interactions generate R22(6 loops. The dimers are linked by further C—H...O interactions to generate [1-10] chains.

  3. 2-Benzylsulfanyl-N-(1,3-dimethylimidazolidin-2-ylideneaniline

    Directory of Open Access Journals (Sweden)

    Ulrich Flörke

    2013-04-01

    Full Text Available The molecular structure of the title compound, C18H21N3S, shows a twisted conformation with a dihedral angle of 67.45 (4° between the aromatic ring planes and an N—C—C—S torsion angle of −5.01 (13°. The imidazolidine ring and the aniline moiety make a dihedral angle of 56.03 (4° and the asscociated C—N—C angle is 125.71 (10°. The guanidine-like C=N double bond is clearly localized, with a bond length of 1.2879 (14 Å. The C—S—C angle is 102.12 (5° and the S—C(aromatic and S—C bond lengths are 1.7643 (11 and 1.8159 (12 Å.

  4. Tribenzylammonium chloride

    Directory of Open Access Journals (Sweden)

    Waly Diallo

    2014-05-01

    Full Text Available Single crystals of the title salt, C21H21NH+·Cl−, were isolated as a side product from the reaction involving [(C6H5CH23NH]2[HPO4] and Sn(CH33Cl in ethanol. Both the cation and the anion are situated on a threefold rotation axis. The central N atom in the cation has a slightly distorted tetrahedral environment, with angles ranging from 107.7 to 111.16 (10°. In the crystal, the tribenzylammonium cations and chloride anions are linked through N—H...Cl and C—H...Cl hydrogen bonds, leading to the formation of infinite chains along [001]. The crystal studied was a merohedral twin.

  5. trans-Carbonylchloridobis(tri-p-tolylphosphinerhodium(I acetone solvate

    Directory of Open Access Journals (Sweden)

    Brian R. James

    2008-03-01

    Full Text Available The title compound, [RhCl(C21H21P2(CO]·C3H6O, was precipitated in trace yield from a reaction of RhCl(cod(THP with P(p-tol3 in a 1:1 acetone-d6/CD3OD solution under a hydrogen atmosphere [p-tol = p-tolyl, THP = tris(hydroxymethylphosphine, P(CH2OH3, and cod = 1,5-cyclooctadiene]. The complex displays a square-planar geometry around the RhI atom. The complex molecules and the acetone molecules are linked into a chain along the a axis by intermolecular C—H...Cl and C—H...O hydrogen bonds.

  6. DECENTRALIZATION, FISCAL CAPABILITY AND PUBLIC SPENDING EFFICIENCY

    Directory of Open Access Journals (Sweden)

    Abdul Hakim

    2012-01-01

    Full Text Available Assigning autonomy to regency governments in Indonesia has failed to increase regency’s economies.While it increases regency government role in planning and initiating policies, its impact oneconomic development has been insignificant. This stems from the lack of institution’s capacity inorganizing the bulk funds transfer from the central government which leads to inefficiency in resourceallocation. This paper maps these regencies based on their fiscal dependency. This paperalso applies Data Envelopment Analysis to identify the efficient and non efficient regencies in sucha way that the non efficient regencies might use the efficient ones as the benchmark to increase theirefficiency.Keywords: Autonomy, regency government, efficiencyJEL classification numbers: H21, H53, H71, H72

  7. (R-2-[(Dimethylaminomethyl]-1,1′-bis(diphenylphosphinothioylferrocene dichloromethane monsolvate

    Directory of Open Access Journals (Sweden)

    Elisabeth Philippe

    2012-06-01

    Full Text Available In the title compound, [Fe(C20H21NPS(C17H14PS]·CH2Cl2, both cyclopentadienyl (Cp rings constituting the ferrocene unit are substituted by a sulfur-protected diphenylphosphine. One of the Cp ligands is additionally substituted by a dimethylaminomethyl group causing the chirality of the molecule. Surprisingly, although the synthetic procedure yielded the title compound as a racemic mixture, the reported crystal is enantiomerically pure with the R absolute configuration. The dimethylamino group is exo with respect to the Cp ring. Both diphenylthiophosphine groups are trans with respect to the centroid–Fe–centroid direction. Weak intramolecular C—H...S and C—H...π interactions between symmetry-related molecules are observed. The contribution of the disordered solvent was removed from the refinement using SQUEEZE in PLATON [Spek (2009. Acta Cryst. D65, 148–155].

  8. 1-Decyl-6-nitro-1H-benzimidazol-2(3H-one

    Directory of Open Access Journals (Sweden)

    Younes Ouzidan

    2011-11-01

    Full Text Available The title molecule, C17H25N3O3, is built up from fused six- and five-membered rings linked to a –C10H21 chain. The fused-ring system is essentially planar, the largest deviation from the mean plane being 0.009 (2 Å. The chain is roughly perpendicular to this plane, making a dihedral angle of 79.5 (2°. In the crystal, N—H...O hydrogen bonds build infinite chains along [010]. There are channels in the structure containing disordered hexane. The contribution of this solvent to the scattering power was suppressed using the SQUEEZE option in PLATON [Spek (2009. Acta Cryst. D65, 148–155].

  9. Tris(4-methoxyphenylphosphine selenide

    Directory of Open Access Journals (Sweden)

    Melina Raymundo

    2016-08-01

    Full Text Available The title compound, C21H21O3PSe, is comprised of a P atom in a distorted tetrahedral environment, attached to the Se atom and three C atoms of the phenyl rings. The P—Se bond length is 2.1214 (12 Å. All three methoxy groups are near coplanar with their respective phenyl rings, with the angles between the phenyl ring and the C—O bond of the methoxy groups being 5.7 (2, 1.5 (4, and 5.7 (3°. The torsion angles of the phenyl rings relative to the P=Se bond are 35.62 (10, 35.07 (13, and 44.50 (11°. No strong intermolecular interactions were observed, but that in addition to van der Waals forces, there are C—H...π and C—H...Se close contacts.

  10. Synthesis and structural study of 4-(2-chlorophenyl)-2-ethoxy-5,6,7,8,9,10-hexahydrocycloocta[B]pyridine-3-carbonitrile

    Science.gov (United States)

    Fathima, K. Saiadali; Vasumathi, M.; Anitha, K.

    2016-05-01

    The novel organic material C20H21ClN2O was synthesized by One-Pot synthesis method and the single crystals were grown by slow evaporation solution growth technique. The crystal structure was elucidated by subjecting the grown crystals to the single crystal x-ray diffraction analysis and was refined by full matrix least-squares method to R=0.039 for 2746 reflections. Crystal system of the grown crystal was found to be monoclinic with the space group P21/a and a=9.196(4) Å, b=13.449(4) Å, c=14.818(4) Å, β= 101.542(3)°, V=1795.6(11) Å3 and Z=4. In this crystal structure, cyclooctanone prefers to reside in a chair-boat conformation. The structure is stabilized by attractive molecular force such as CH/π interaction called hydrophobic interaction.

  11. Sõda on poliitika jätkamine teiste vahenditega : kuidas Euroopa ja USA on jõudnud Iraagi sõja õhtule / Toomas Hendrik Ilves

    Index Scriptorium Estoniae

    Ilves, Toomas Hendrik, 1953-

    2003-01-01

    Järg Eesti Päevaleht : Eriväljaanne 20. märts lk. 3 (lüh.) ; 21. märts lk. 3 "Maailmakord pärast Iraagi sõda" (täistekst) ;15. aprill lk. 3 "Tavalised vahendid pärast sõda". Autor selgitab, millised sajandite kogemused on viinud Euroopa ja USA tüli ning Iraagi sõjani. Iraagi sõja mõjust maailma uuele julgeolekusüsteemile.USA visioon sõjajärgsest Iraagist ja Lähis-Idast. USA võidu mõju Lähis-Ida rahvastele ja riikidele, Venemaale. Arvete klaarimine minevikuga kui Iraagi demokratiseerimise võtmeküsimus. Kommenteerivad Henry Kissinger ja Francis Fukuyama

  12. Tris(4-methyl­phen­yl)phosphine selenide

    Science.gov (United States)

    Muller, Alfred

    2011-01-01

    In the title mol­ecule, C21H21PSe or PSe(C7H7)3, the P atom has a distorted PSeC3 tetra­hedral environment, formed by the Se atom [P=Se = 2.1119 (5) Å] and three aryl rings. Two short intra­molecular C—H⋯Se contacts occur. In the crystal, weak inter­molecular C—H⋯Se inter­actions link the mol­ecules into zigzag double chains propagating in [100]. The previous report of this structure [Zhdanov et al. (1953 ▶). Dokl. Akad. Nauk SSSR (Russ.) (Proc. Nat. Acad. Sci. USSR), 92, 983–985] contained no geometrical data. PMID:21522754

  13. Tris(4-methyl-phen-yl)phosphine selenide.

    Science.gov (United States)

    Muller, Alfred

    2010-12-08

    In the title mol-ecule, C(21)H(21)PSe or PSe(C(7)H(7))(3), the P atom has a distorted PSeC(3) tetra-hedral environment, formed by the Se atom [P=Se = 2.1119 (5) Å] and three aryl rings. Two short intra-molecular C-H⋯Se contacts occur. In the crystal, weak inter-molecular C-H⋯Se inter-actions link the mol-ecules into zigzag double chains propagating in [100]. The previous report of this structure [Zhdanov et al. (1953 ▶). Dokl. Akad. Nauk SSSR (Russ.) (Proc. Nat. Acad. Sci. USSR), 92, 983-985] contained no geometrical data.

  14. Structure-Triggered High Quantum Yield Luminescence and Switchable Dielectric Properties in Manganese(II) Based Hybrid Compounds.

    Science.gov (United States)

    Wang, Zhong-Xia; Li, Peng-Fei; Liao, Wei-Qiang; Tang, Yuanyuan; Ye, Heng-Yun; Zhang, Yi

    2016-04-01

    Two new manganese(II) based organic-inorganic hybrid compounds, C11H21Cl3MnN2 (1) and C11H22Cl4MnN2 (2), with prominent photoluminescence and dielectric properties were synthesized by solvent modulation. Compound 1 with novel trigonal bipyramidal geometry exhibits bright red luminescence with a lifetime of 2.47 ms and high quantum yield of 35.8 %. Compound 2 with tetrahedral geometry displays intense long-lived (1.54 ms) green light emission with higher quantum yield of 92.3 %, accompanied by reversible solid-state phase transition at 170 K and a distinct switchable dielectric property. The better performance of 2 results from the structure, including a discrete organic cation moiety and inorganic metal anion framework, which gives the cations large freedom of motion.

  15. A new layered iron fluorophosphate

    Indian Academy of Sciences (India)

    Amitava Choudhury

    2002-04-01

    A new iron fluorophosphate of the composition, [C6N4H21] [Fe2F2(HPO4)3][H2PO4]·2H2O, I has been prepared by the hydrothermal route. This compound contains iron fluorophosphate layers and the H2PO$_{4}^{-}$ anions are present in the interlayer space along with the protonated amine and water molecules. The compound crystallizes in the monoclinic space group 21/. ( = 13.4422(10) Å, = 9.7320(10) Å, = 18.3123(3) Å, = 92.1480 °, = 2393.92(5) Å3, = 4, = 719.92, calc = 1.997 g cm-3, 1 = 0.03 and 2 = 0.09).

  16. N-[7-Ethoxy-1-(prop-2-en-1-yl-1H-indazol-4-yl]-4-methylbenzenesulfonamide

    Directory of Open Access Journals (Sweden)

    Najat Abbassi

    2011-07-01

    Full Text Available In the title compound, C19H21N3O3S, the C—SO2—NH—C torsion angle is 103.72 (11°. The almost planar indazole ring [r.m.s. deviation = 0.0202 (14 Å] is twisted away from the methylbenzene ring by 76.87 (7°. The vinyl group is disordered over two orientations with site occupancies of 0.622 (10 and 0.378 (10. The S atom has a distorted tetrahedral geometry [maximum deviation: O—S—O = 119.18 (11°]. An intramolecular C—H...O hydrogen bond occurs. In the crystal, two molecules are linked about a center of inversion by pairs of N—H...O hydrogen bonds, generating a dimer. C—H...π interactions are also observed.

  17. (±-N-[4-Acetyl-5-methyl-5-(4-methylcyclohex-3-enyl-4,5-dihydro-1,3,4-thiadiazol-2-yl]acetamide

    Directory of Open Access Journals (Sweden)

    Ahmed Benharref

    2008-03-01

    Full Text Available The new title thiadiazole compound, C14H21N3O2S, was semi-synthesized starting from 1-(4-methylcyclohex-3-enylethanone, a natural product isolated from Cedrus atlantica essential oil. The stereochemistry has been confirmed by single-crystal X-ray diffraction. The thiadiazoline ring is roughly planar, although it may be regarded as having a half-chair conformation. The cyclohexenyl ring has a half-chair conformation. The most interesting feature is the formation of a pseudo-ring formed by four molecules associated through N—H...O hydrogen bonds around a fourfold inversion axis, forming an R44(28 motif.

  18. (±)-N-[4-Acetyl-5-methyl-5-(4-methyl-cyclo-hex-3-en-yl)-4,5-dihydro-1,3,4-thia-diazol-2-yl]acetamide.

    Science.gov (United States)

    Mohammed, Tebbaa; Mazoir, Noureddine; Daran, Jean-Claude; Berraho, Moha; Benharref, Ahmed

    2008-02-20

    The new title thiadiazole compound, C(14)H(21)N(3)O(2)S, was semi-synthesized starting from 1-(4-methyl-cyclo-hex-3-en-yl)ethanone, a natural product isolated from Cedrus atlantica essential oil. The stereochemistry has been confirmed by single-crystal X-ray diffraction. The thia-diazo-line ring is roughly planar, although it may be regarded as having a half-chair conformation. The cyclo-hexenyl ring has a half-chair conformation. The most inter-esting feature is the formation of a pseudo-ring formed by four mol-ecules associated through N-H⋯O hydrogen bonds around a fourfold inversion axis, forming an R(4) (4)(28) motif.

  19. Tri-μ-ethanethiolato-bis{[η5-1,2,3,4-tetramethyl-5-(trimethylsilylcyclopentadienyl]iron(II,III}(FeII–FeIII

    Directory of Open Access Journals (Sweden)

    Jing Li

    2009-12-01

    Full Text Available The title complex, [Fe2(C2H5S3(C12H21Si2], has an unusual Fe2S3 core. The two 1,2,3,4-tetramethyl-5-(trimethylsilylcyclopentadienyl (Cp′ ligands coordinate to the Fe atoms with their C5 planes perpendicular [dihedral angles = 88.23 (7 and 88.55 (7°] to the Fe—Fe vector, building two Cp′Fe subunits. These two subunits are bridged by three thiolate ligands. There are no significant differences in the coordination geometries between the two Fe atoms. The short Fe—Fe distance of 2.7842 (5 Å is clear evidence of an intermetallic bond. Such a diiron–sulfur structure might act as a model of active sites in some metalloproteins.

  20. Petroleum hydrocarbon persistence following the Deepwater Horizon oil spill as a function of shoreline energy.

    Science.gov (United States)

    Evans, Meredith; Liu, Jiqing; Bacosa, Hernando; Rosenheim, Brad E; Liu, Zhanfei

    2017-02-15

    An important aspect of oil spill science is understanding how the compounds within spilled oil, especially toxic components, change with weathering. In this study we follow the evolution of petroleum hydrocarbons, including n-alkanes, polycyclic aromatic hydrocarbons (PAHs) and alkylated PAHs, on a Louisiana beach and salt marsh for three years following the Deepwater Horizon spill. Relative to source oil, we report overall depletion of low molecular weight n-alkanes and PAHs in all locations with time. The magnitude of depletion, however, depends on the sampling location, whereby sites with highest wave energy have highest compound depletion. Oiled sediment from an enclosed bay shows high enrichment of high molecular weight PAHs relative to 17α(H),21β(H)-hopane, suggesting the contribution from sources other than the Deepwater Horizon spill, such as fossil fuel burning. This insight into hydrocarbon persistence as a function of hydrography and hydrocarbon source can inform policy and response for future spills.

  1. Measuring Tax Efficiency

    DEFF Research Database (Denmark)

    Raimondos-Møller, Pascalis; Woodland, Alan D.

    2004-01-01

    This paper introduces an index of tax optimality thatmeasures the distance of some current tax structure from the optimal taxstructure in the presence of public goods. In doing so, we derive a [0, 1]number that reveals immediately how far the current tax configurationis from the optimal one and......, thereby, the degree of efficiency of a taxsystem. We call this number the Tax Optimality Index. We show howthe basic method can be altered in order to derive a revenue equivalentuniform tax, which measures the size of the public sector. A numericalexample is used to illustrate the method developed.......JEL Code: H21, H41.Keywords: Tax optimality index, excess burden, distance function.Authors Affiliations: Raimondos-Møller: Copenhagen Business School, CEPR,CESifo, and EPRU. Woodland: University of Sydney....

  2. Bis(μ-diisopropylphosphanido-κ2P:Pbis[hydrido(triisopropylphosphane-κPplatinum(II

    Directory of Open Access Journals (Sweden)

    Nicole Arnold

    2012-06-01

    Full Text Available In the centrosymmetric molecular structure of the title compound [Pt2(C6H14P2H2(C9H21P2], each PtII atom is bound on one side to a phosphane ligand (PiPr3 and a hydrido ligand. On the other side, it is bound to two phosphanide ligands (μ-PiPr2, which engage a bridging position between the two PtII atoms, forming a distorted square-planar structure motif. The Pt...Pt distance is 3.6755 (2 Å. A comparable molecular structure was observed for bis(μ-di-tert-butylphosphanidobis[hydrido(triethylphosphaneplatinum(II] [Itazaki et al. (2004. Organometallics, 23, 1610–1621].

  3. Crystal growth and characterization studies of novel luminescent 2D coordination polymer of lead-benzilate possessing edge sharing PbO6 polyhedra

    Science.gov (United States)

    Soumya Mol, U. S.; Drisya, R.; Satheesh Chandran, P. R.; Sudarsanakumar, M. R.; Suma, S.; Sudhadevi Antharjanam, P. K.

    2016-12-01

    Single crystals of a new coordination polymer of lead-benzilate, C28H21O6Pb·C2H5OH have been successfully grown by gel diffusion technique at room temperature. The colourless single crystals were obtained within a week. The crystal structure was elucidated using single crystal X-ray diffraction studies. The compound possesses a polymeric structure constructed from edge sharing PbO6 polyhedra. Single crystal X-ray diffraction analysis showed that the compound crystallizes in triclinic space group P-1. The grown crystals were further characterized by elemental analysis, FT-IR, UV-Visible and thermogravimetric analysis. The photoluminescent properties of the complex and the ligand were also investigated.

  4. Improved Bunch Splitting for the 75ns LHC Beam

    CERN Document Server

    Damerau, H

    2011-01-01

    The 75ns variant was added to the PS arsenal of LHC-type beams by adapting the 20MHz cavity used to produce the 25 and 50ns variants to operate at a switchable 13MHz. This permitted splitting from harmonic 14 to 28, but at a cost in adiabaticity compared with the h=2142 splitting of the other two cases. Consequently, a delicate empirical optimization was necessary to bring the 75ns beam inside specification. More recently the speed at which the bunches, once fully distinct, are moved apart has been revisited and further optimization achieved. As a by-product, deliberately degrading the splitting by moving the bunches apart too quickly led to sufficient coherent motion in the resultant bunch pair to permit a voltage calibration of the 13MHz cavity by means of the influence on convergence of the rf voltage input into the iterative algorithm of the Tomoscope [1,2].

  5. 6-Benzyl-3,4-dimethoxy-10-methylpyrido[2′,1′:2,3]imidazo[4,5-c]isoquinolin-5(6H-one

    Directory of Open Access Journals (Sweden)

    Kathrin Meindl

    2009-10-01

    Full Text Available Pyrido[2′,1′:2,3]imidazo[4,5-c]isoquinolin-5(6H-ones such as the title compound, C24H21N3O3, can be obtained in a few minutes in a microwave-assisted three-component reaction from 2-aminopyridines, isocyanides and 2-carboxybenzaldehydes. In the title compound, the pyrido[2′,1′:2,3]imidazo[4,5-c]isoquinolin-5(6H-one ring system is almost planar (mean deviation 0.068 Å. The dihedral angle between the benzyl ring and the pyrido[2′,1′:2,3]imidazo[4,5-c]isoquinolin-5(6H-one ring system is 78.2°. The crystal structure is stabilized by intermolecular C—H...O and C—H...N hydrogen bonds.

  6. Theoretical Investigation on the Adsorption of Ag+ and Hydrated Ag+ Cations on Clean Si(111)Surface

    Institute of Scientific and Technical Information of China (English)

    SHENG Yong-Li; LI Meng-Hua; WANG Zhi-Guo; LIU Yong-Jun

    2008-01-01

    In this paper,the adsorption of Ag+ and hydrated Ag+ cations on clean Si(111)surface were investigated by using cluster(Gaussian 03)and periodic(DMol3)ab initio calculations.Si(111)surface was described with cluster models(Si14H17 and Si22H21)and a four-silicon layer slab with periodic boundary conditions.The effect of basis set superposition error(BSSE)was taken into account by applying the counterpoise correction.The calculated results indicated that the binding energies between hydrated Ag+ cations and clean Si(111)surface are large,suggesting a strong interaction between hydrated Ag+ cations and the semiconductor surface.With the increase of number,water molecules form hydrogen bond network with one another and only one water molecule binds directly to the Ag+ cation.The Ag+ cation in aqueous solution will safely attach to the clean Si(111)surface.

  7. Synthesis and Crystal Structure of 2-(N-Cyclohexyl)-imino-1,4-succinic Acid Dihydrate

    Institute of Scientific and Technical Information of China (English)

    郭金波; 李森兰; 郁兆莲; 陈庆华

    2005-01-01

    The title compound, 2-(N-cyclohexyl)-imino-1,4-succinic acid dihydrate 4, has been prepared and structurally determined by X-ray diffraction analysis. Crystal data: monoclinic, space group Cc, a = 7.5790(15), b = 24.860(5), c = 7.1394(14)(A), β = 104.23(3)°, V = 1303.9(4) (A)3, C10H21NO6, Mr = 251.28, Z = 4, Dc = 1.280 g/cm3, μ = 0.105 mm-1, F(000) = 544, R = 0.0397 and wR = 0.0918 for 1212 observed reflections with I ≥ 2σ(I). X-ray structure analysis reveals that there exist two intramolecular and six intermolecular hydrogen-bonding interactions in the crystal lattice, which can stabilize the configuration of the α-imino acid dihydrate 4.

  8. 4,4-Difluoro-2,3;5,6-bis(tetramethylene-4-bora-3a,4a-diaza-s-indacene (LD540

    Directory of Open Access Journals (Sweden)

    Kirsi Salorinne

    2014-01-01

    Full Text Available The title compound, C18H21BF2N2, is a lipophilic dye based on a BODIPY fluorophore backbone, which was developed for microscopic imaging of lipid droplets; the molecule has a planar BODIPY core [dihedral angle between the pyrrole rings = 2.3 (3°] and two tetramethylene substituents at the 2,3- and 5,6-positions in a half-chair conformation. One of the tetramethylene substituents is disordered over two two sets of sites with site occupancies of 0.5. In the crystal, pairs of C—H...F interactions link the molecules into inversion dimers. Neighbouring dimers are linked by further C—H...F interactions, forming an infinite array. C—H...π and π–π [centroid–centroid distance = 4.360 (3 Å] interactions are observed between the BODIPY core and the tetramethylene substituents of neighbouring dimer pairs.

  9. Methyl trans-(±-1-oxo-2-phenethyl-3-(thiophen-2-yl-1,2,3,4-tetrahydroisoquinoline-4-carboxylate

    Directory of Open Access Journals (Sweden)

    Mehmet Akkurt

    2009-06-01

    Full Text Available In the title compound, C23H21NO3S, the piperidine ring of the tetrahydroisoquinolinone unit adopts a screw-boat conformation. The thiophene ring is disordered in a 0.700 (3:0.300 (3 ratio by an approximate 180° rotation of the ring around the C—C bond linking the ring to the tetrahydroisoquinolinone unit. The benzene ring of the tetrahydroisoquinolinone unit makes dihedral angles of 83.1 (2 and 62.38 (11° with the major occupancy thiophene ring and the phenyl ring, respectively. The dihedral angle between the phenyl ring and the thiophene ring is 71.0 (2°. In the crystal structure, molecules are linked together by intermolecular C—H...O and C—H...π interactions.

  10. Methyl (3R*,3′S*-1′,1′′-dimethyl-2,2′′-dioxodispiro[indoline-3,2′-pyrrolidine-3′,3′′-indoline]-4′-carboxylate

    Directory of Open Access Journals (Sweden)

    G. Ganesh

    2012-10-01

    Full Text Available In the title compound, C22H21N3O4, the central pyrrolidine ring adopts an envelope conformation with the N atom in the flap position. The indoline ring systems are almost perpendicular to the mean plane of the pyrrolidine ring, making dihedral angles of 86.4 (8 and 83.1 (8°. The acetate group attached to the pyrrolidine ring assumes an extended conformation. In thecrystal, N—H...O hydrogen bonds result in the formation of a C(7 chain running along [100]. The crystal packing also features π–π interactions [centroid–centroid distance = 3.2032 (11 Å].

  11. (2E-3-(6-Chloro-2-methoxyquinolin-3-yl-1-(2-methyl-4-phenylquinolin-3-ylprop-2-en-1-one acetone monosolvate

    Directory of Open Access Journals (Sweden)

    Edward R. T. Tiekink

    2013-08-01

    Full Text Available In the title solvate, C29H21ClN2O2·C3H6O, a prop-2-en-1-one bridge links two quinolinyl residues; the latter are almost perpendicular [dihedral angle = 78.27 (6°]. The dihedral angle between the quinonyl ring system and its pendant phenyl group is 59.78 (8°. A small twist in the bridging prop-2-en-1-one group is noted [O=C—C=C torsion angle = −10.6 (3°]. In the crystal, a three-dimensional architecture arises as a result of C—H...O and π–π stacking [centroid–centroid distances = 3.5504 (12–3.6623 (12 Å].

  12. Phylogenetic and molecular analysis of food-borne shiga toxin-producing Escherichia coli.

    Science.gov (United States)

    Hauser, Elisabeth; Mellmann, Alexander; Semmler, Torsten; Stoeber, Helen; Wieler, Lothar H; Karch, Helge; Kuebler, Nikole; Fruth, Angelika; Harmsen, Dag; Weniger, Thomas; Tietze, Erhard; Schmidt, Herbert

    2013-04-01

    Seventy-five food-associated Shiga toxin-producing Escherichia coli (STEC) strains were analyzed by molecular and phylogenetic methods to describe their pathogenic potential. The presence of the locus of proteolysis activity (LPA), the chromosomal pathogenicity island (PAI) PAI ICL3, and the autotransporter-encoding gene sabA was examined by PCR. Furthermore, the occupation of the chromosomal integration sites of the locus of enterocyte effacement (LEE), selC, pheU, and pheV, as well as the Stx phage integration sites yehV, yecE, wrbA, z2577, and ssrA, was analyzed. Moreover, the antibiotic resistance phenotypes of all STEC strains were determined. Multilocus sequence typing (MLST) was performed, and sequence types (STs) and sequence type complexes (STCs) were compared with those of 42 hemolytic-uremic syndrome (HUS)-associated enterohemorrhagic E. coli (HUSEC) strains. Besides 59 STs and 4 STCs, three larger clusters were defined in this strain collection. Clusters A and C consist mostly of highly pathogenic eae-positive HUSEC strains and some related food-borne STEC strains. A member of a new O26 HUS-associated clone and the 2011 outbreak strain E. coli O104:H4 were found in cluster A. Cluster B comprises only eae-negative food-borne STEC strains as well as mainly eae-negative HUSEC strains. Although food-borne strains of cluster B were not clearly associated with disease, serotypes of important pathogens, such as O91:H21 and O113:H21, were in this cluster and closely related to the food-borne strains. Clonal analysis demonstrated eight closely related genetic groups of food-borne STEC and HUSEC strains that shared the same ST and were similar in their virulence gene composition. These groups should be considered with respect to their potential for human infection.

  13. Research of Catalytic Oxidation of 2-mercaptoethanol by Asymmetric Phthalocyanine Cobalt%非对称酞菁钴催化氧化2-巯基乙醇的研究

    Institute of Scientific and Technical Information of China (English)

    梁雅秋; 潘玲玲; 单秋杰; 吴迪; 陈伟

    2015-01-01

    采用统计缩合法合成三种不对称酞菁钴———2-(对羧基苯氧基)-9,10,16,17,23,24-六烷氧基酞菁钴(Ⅱ)CoPc (n-C4 H9, n-C5 H11, n-C10 H21)( a, b, c)。研究了催化剂对2-巯基乙醇的催化氧化性能。探讨了催化剂种类、催化剂用量对2-巯基乙醇催化氧化反应的影响。实验结果表明:在相同的催化条件下,三种催化剂均表现出良好的催化性能,在60 min内,能将0.10 mol· L-1的2-巯基乙醇氧化77%。%Three novel asymmetrical phthalocyanines cobalt (Ⅱ) , 2-( p-carboxylphenoxy )-9 ,10 ,16 ,17 ,23 ,24-hexaalkoxyphthalocyanine cobalt(Ⅱ)[(RO)6(OphCOOH)PcCo(Ⅱ)](R=n-C4H9, n-C5H11, n-C10H21)(a,b,c), were synthesized by statistical condensation method.The catalytic performance of catalysts for 2-mercaptoethanol , effects of catalyst type , catalyst dosage on the catalytic oxidation of 2-mercaptoethanol were studied.The experimental results showed that three kinds of catalysts showed good catalytic performance in the same catalytic conditions , the 0.10 mol· L-1 2-mercaptoethanol of 77%was oxidized in the 60 min.

  14. Circadian response of annual weeds to glyphosate and glufosinate.

    Science.gov (United States)

    Martinson, Krishona B; Sothern, Robert B; Koukkari, Willard L; Durgan, Beverly R; Gunsolus, Jeffrey L

    2002-03-01

    Five field experiments were conducted in 1998 and 1999 in Minnesota to examine the influence of time of day efficacy of glyphosate [N-(phosphonomethyl)glycine] and glufosinate [2-amino-4-(hydroxymethyl-phosphinyl)butanoic acid] applications on the control of annual weeds. Each experiment was designed to be a randomized complete block with four replications using plot sizes of 3 x 9 m. Glyphosate and glufosinate were applied at rates of 0.421 kg ae/ha and 0.292 kg ai/ha, respectively, with and without an additional adjuvant that consisted of 20% nonionic surfactant and 80% ammonium sulfate. All treatments were applied with water at 94 L/ha. Times of day for the application of herbicide were 06:00h, 09:00h, 12:00h, 15:00h, 18:00h, 21:00h, and 24:00h. Efficacy was evaluated 14 d after application by visual ratings. At 14 d, a circadian response to each herbicide was found, with greatest annual weed control observed with an application occurring between 09:00h and 18:00h and significantly less weed control observed with an application at 06:00h, 21:00h, or 24:00h. The addition of an adjuvant to both herbicides increased overall efficacy, but did not overcome the rhythmic time of day effect. Results of the multiple regression analysis showed that after environmental temperature, time of day was the second most important predictor of percent weed kill. Thus, circadian timing of herbicide application significantly influenced weed control with both glyphosate and glufosinate.

  15. Functional studies of the gene slr2049 from Synechocystis sp. PCC6803 and its site-directed mutation.

    Science.gov (United States)

    Liu, Bingjun; Chen, Sili; Zhang, Lei

    2015-06-01

    Phycobiliprotein is a homologous family of light-harvesting chromoproteins existing in cyanobacteria, red algae and cryptophytes. Phycobiliprotein is made up of phycobilin and its corresponding apophycobiliprotein, and they are covalently linked by the thioether bond with the bilin lyase. Using the software BLAST, we have found gene slr2049 in Synechocystis sp. PCC6803 homologous to the biliprotein lyase gene cpeS. This paper investigates the protein expressed by gene slr2049 to find the enzymatic activity characteristics. We cloned slr2049 and its related genes cpcB, ho1, and pcyA which are linked with the synthesis of phycocyanin. Special amino acid mutagenesis was performed on slr2049 to construct eight mutants slr2049 (H21S), slr2049 (L23S), slr2049 (A24S), slr2049 (F25S), slr2049 (W72L), slr2049 (G84S), slr2049 (R107S) and slr2049 (Y124S). These mutants were ligated with vectors pEDFDuet-1 and pET-23a to construct pCDF-cpcB-slr2049 wild-type, pCDF-cpcB-slr2049 mutants and pET-ho1-pcyA, for the purpose of protein expression and analysis. The results showed that the wild-type and mutants slr2049 (H21S), slr2049 (L23S), slr2049 (F25S), slr2049 (W72L), slr2049 (G84S), and slr2049 (Y124S) can catalyze CpcB to couple on PCB correctly and the products have unique spectral characteristics. However mutants slr2049 (A24S) and slr2049 (R107S) have no spectral characteristics. Thus, it is suggested that alanine at position 24 and arginine at position 107 are the active sites.

  16. Solid pole tide in global GPS and superconducting gravimeter observations: Signal retrieval and inference for mantle anelasticity

    Science.gov (United States)

    Ding, Hao; Chao, Benjamin F.

    2017-02-01

    The mantle anelasticity plays an important role in Earth's interior dynamics. Here we seek to determine the lower-mantle anelasticity through the solution of the complex Love numbers at the Chandler wobble period. The Love numbers h21, l21, δ21 and k21 are obtained in the frequency domain by dividing off the observed polar motion, or more specifically the pole tide potential, from the observed GPS 3-D displacement field and SG gravity variation. The latter signals are obtained through the array processing method of OSE (optimal sequence estimation) that results in greatly enhanced signals to be extracted from global array data. The resultant Love number estimates h21 = 0.6248 (± 5 e - 4) - 0.013 (± 5 e - 3) i, l21 = 0.0904 (± 8 e - 4) - 0.0008 (± 2 e - 3) i, δ21 = 1.156 (± 2 e - 3) - 0.003 (± 1 e - 3) i and k21 = 0.3125 (± 2 e - 3) - 0.0069 (± 3 e - 3) i are thus well-constrained in comparison to past estimates that vary considerably. They further lead to estimates of the corresponding mantle anelastic parameters fr and fi, which in turn determines, under the single-absorption band assumption, the dispersion exponent of α = 0.21 ± 0.02 with respect to the reference frequency of 5 mHz. We believe our estimate is robust and hence can better constrain the mantle anelasticity and attenuation models of the Earth interior.

  17. 墨西哥湾陆坡区冷泉碳酸盐岩的烷烃分布特征%Alkane distributions of seep-carbonates from the slopes of Gulf of Mexico

    Institute of Scientific and Technical Information of China (English)

    管红香; 陈多福; 冯东; 吴能友

    2009-01-01

    对墨西哥湾北部水深2 200m 的Alaminos Canyon 645区块(AC 645区)和水深540m的Green Canyon 185区块(GC 185区)冷泉碳酸盐岩的有机质进行了研究,结果显示深水和浅水区冷泉碳酸盐岩的有机质丰度和烷烃组成差别较大,下陆坡深水AC区样品有机质含量低,正构烷烃、萜烷、甾烷各组分的含量相对较高,正构烷烃以低碳数占绝对优势,并含有种类丰富的三环萜烷和五环三萜烷,且以17α(H),21β(H)-藿烷为主峰碳,反映了深水区冷泉碳酸盐岩的有机质来源于细菌和低等藻类,有少量的深部油气藏有机质的渗漏输入,并受微弱的微生物作用改造.上陆坡浅水GC区样品有机质含量较高,其中正构烷烃含量较低,并且以难以分开的复杂混合物(UCM)为主,同样含有种类丰富的以17α(H),21β(H)-降藿烷为主峰碳的三环萜烷和五环三萜烷,表明有机质主要来源于深部油气藏渗漏的有机质,并遭受了强烈的微生物降解.本文系统地研究了冷泉碳酸盐岩中正构烷烃、萜烷、甾烷的组成和分布特征,并探讨了有机质来源和冷泉渗漏的关系.

  18. Hadron rich and Centauro events

    Energy Technology Data Exchange (ETDEWEB)

    Barroso, S.L.C. [Centro Brasileiro de Pesquisas Fisicas, 22290-180 Rio de Janeiro, RJ (Brazil); Beggio, P.C. [Laboratorio de Ciencias Matematicas, UENF, Campos de Goytacazes, RJ (Brazil); Carvalho, A.O. de; Chinellato, J.A.; Mariano, A.; Oliveira, R. de; Shibuya, E.H. [Instituto de Fisica ' Gleb Wataghin' /UNICAMP, 13083-970 Campinas, SP (Brazil)

    2008-01-15

    An exploratory statistical analysis of the event C16S086I037 was possible to do using two simulations. A {gamma} and hadron induced showers recognition done on this event through a best fitting procedure shows identification of 25 and 37 for {gamma} and hadron induced showers, respectively. Assuming that the most energetic shower is the surviving particle of an interaction and the tertiary produced particles are from normal multiple pion production, the characteristics of the interaction are: Energy of primary particle E{sub 0}=1,061 TeV, Inelasticity of collision K=0.81, Mean inelasticity of {gamma}-ray =0.27, Hadron induced showers energy/Total energy Q{sub h}{sup '}=0.90{approx}Q{sub h}, Rapidity density N{sub h}/{delta}Y=(8.56-9.89), Mean energy of secondary hadrons h}>=(21.5{+-}4) TeV, Mean transverse momentum =(1.2{+-}0.2) GeV/c, Upper bound of partial cross section {sigma}{<=}(15-39){mu}barn and life time {tau}{<=}10{sup -16} s. Without the surviving particle assumption, the values are: E{sub 0}=873 TeV, K=1.0, =1/3, Q{sub h}{sup '}=0.90, N{sub h}/{delta}Y=(8.32-9.34), h}>=(21{+-}3.5) TeV, =(1.0{+-}0.16) GeV/c. Using another simulation for energy determination with {chi}{sup 2}>3.16 for best fitting results 22 and 40 for {gamma} and hadron induced showers, respectively. Under the surviving particle assumption, the figures are: Energy of primary particle E{sub 0}=1,047 TeV, Inelasticity of collision K=0.80, Mean inelasticity of {gamma}-ray =0.27, Hadronic induced showers energy/Total energy Q{sub h}{sup '}=0.89{approx}Q{sub h}, Rapidity density N{sub h}/{delta}Y=(10.25-13.19), Mean energy of secondary hadrons =(19{+-}3) TeV, Mean transverse momentum =(1.0{+-}0.2) GeV/c. That is, we get almost similar figures independently of simulation and a mean transverse momentum for this hadron-rich event similar to the Centauro events.

  19. AlGaN/GaN-based HEMT on SiC substrate for microwave characteristics using different passivation layers

    Indian Academy of Sciences (India)

    T R Lenka; A K Panda

    2012-07-01

    In this paper, a new gate-recessed AlGaN/GaN-based high electron mobility transistor (HEMT) on SiC substrate is proposed and its DC as well as microwave characteristics are discussed for Si3N4 and SiO2 passivation layers using technology computer aided design (TCAD). THe two-dimensional electron gas (2DEG) transport properties are discussed by solving Schödinger and Poison equations self-consistently resulting in various subbands having electron eigenvalues. From DC characteristics, the saturation drain currents are measured to be 600 mA/mm and 550 mA/mm for Si3N4 and SiO2 passivation layers respectively. Apart from DC, small-signal AC analysis has been done using two-port network for various microwwave parameters. The extrinsic transconductance parameters are measured to be 131.7 mS/mm at a gate voltage of $V_{gs} = -0.35$ V and 114.6 mS/mm at a gate voltage of $V_{gs} = -0.4$ V for Si3N4 and SiO2 passivation layers respectively. The current gain cut-off frequencies $(f_{t})$ are measured t be 27.1 GHz and 23.97 GHz in unit-gain-point method at a gate voltage of -0.4 V for Si3N4 and SiO2 passivation layers respectively. Similarly, the power gain cut-off frequencied $(f_{max})$ are measured to be 41 GHz and 38.5 GHz in unit-gain-point method at a gate voltage of -0.1 V for Si3N4 and SiO2 passivation layers respectively. Furthermore, the maximum frequency of oscillation or unit power gain (MUG = 1) cut-off frequencies for Si3N4 and SiO2 passivation layers are measured to be 32 GHz and 28 GHz respectively from MUG curves and the unit current gain, $|h_{21}| = 1$ cut-off frequencies are measured to be 140 GHz and 75 GHz for Si3N4 and SiO2 passivation layers respectively from the $abs |h_{21}|$ curves. HEMT with Si3N4 passivation layer giver better results than HEMT with SiO2 passivation layer.

  20. α-氰基-α-二茂铁基乙氧三甲硅烷的合成与晶体结构%Synthesis and Crystal Structure of a Novel Compound-α-cyano-α-ferrocenylethoxytrimethylsilane

    Institute of Scientific and Technical Information of China (English)

    王晓丽; 边占喜; 包华影

    2007-01-01

    乙酰基二茂铁与三甲基氰硅烷在CH2Cl2中ZnI2催化下加成,得到产率较高的α-氰基-α-二茂铁基乙氧三甲硅烷,用元素分析、IR和1H NMR进行了表征.经X射线单晶衍射法测试表明,该化合物属正交晶系,Pbca空间群,晶胞内分子数为8,化合物分子式为C16H21FeNOSi,Mr=327.28,a=1.1995(4)nm,b=1.2441(4)m,c=2.2183(7)nm,β=90°,V=3.3103(18)nm3,Dcale=1.313g·cm-3,Z=8,最终偏离因子R=0.0456,ωR=0.0880.分析其结构表明,该化合物含有一个二茂铁基和氰基乙氧三甲基硅烷基,与二茂铁基相连的碳原子是手性原子,分子中存在超共轭效应.%The title compound, α-cyano-α-ferrocenylethoxytrimethylsilane(C16 H21 FeNOSi,Mr=327.28),was synthesised by the reaction of adding trimethysilyl cynide to acetyfferrocene, in the presence of ZnI2 in CH2 Cl2, and characterized by1H NMR, IR and elemental analysis. The crystal structure was determined by X-ray diffraction methods. The compound crystallises in the orthorhombic space group Pbca, with the cell dimensions of a=1.1995 (4)nm,b = 1.2441 (4) nm,c=2.2183(7)nm,β =90°,V=3.3103 (18)nm3,Z=8,Dcacl =1.313g· cm-3,λ =0. 071073nm,μ(MoKα) =0. 979mm-1 and F(000) =1376. The structure was refined to R =0. 0456 and ωR =0. 0880 for 2148 observed reflections with I>2σ(I). The molecule consists of a ferrocene unit and an ethoxytrimethysilane group and a super conjugate effect may exist in the title compound.

  1. Preparation of Monoclonal Antibody and Development of Enzyme-linked Immunosorbent Assay Specific for Escherichia coli O157 in Foods

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    Objective To prepare monoclonal antibodies (Mab) and antisera specific for Escherichia coli (E.coli) O157, and to develop a sandwich enzyme-linked immunosorbent assay (ELISA) to detect E.coli O157 in foods. Methods Spleen cells from BALB/c mice immunized with the somatic antigen of E.coli O157:H7 were fused with murine Sp2/0 myeloma cells. The hybridoma cell line specific for E.coli O157 was established after having been subcloned. Antisera specific for E.coli O157 was prepared by intravenous injection into New Zealand rabbits with a stain of E.coli O157:H7. The sandwich ELISA was developed with the polyclonal antibody as the capture antibody and the Mab 3A5 as the detection antibody. The inoculated ground poultry meat and pasteurized milk were tested to confirm efficiency of the method. Results Mab 3A5 specific for E.coli O157 and O113:H21 belonged to subtype IgM. The ascetic titers of the antibody was 1:1×106. No cross-reactivity of the Mab was observed with strains of Salmonella spp, Yersinia enterocolitica, Shigella dysenteriae, etc. The purified polyclonal antibody had a titer of 1:1×105 with E.coli O157. The detection limit of this sandwich ELISA was 103-104 cfu E.coli O157/mL in pure culture with a high specificity, which was characterized by every non-O157 strain with negative response. With 10h enrichment procedure, E.coli O157:H7 recovered well from inoculated ground poultry meat and pasteurized milk at levels of 0.1 cfu/g and 0.1 cfu/mL. Conclusion Mab 3A5 specific for E.coli O157 and O113:H21 can be produced by immunizing BALB/c mice with a strain of E.coli O157:H7. Then a sandwich ELISA can be developed with the polyclonal antibody as the capture antibody and the Mab 3A5 as the detection antibody. The method is proved to be a sensitive and specific technique to detect low number of E.coli O157 in food.

  2. Chemical composition of PM2.5 from two tunnels with different vehicular fleet characteristics.

    Science.gov (United States)

    Cui, Min; Chen, Yingjun; Tian, Chongguo; Zhang, Fan; Yan, Caiqing; Zheng, Mei

    2016-04-15

    The chemical compositions of PM2.5 including OC, EC, water soluble ions, elements, and organic components such as polycyclic aromatic hydrocarbons (PAHs), hopanes, and steranes, emitted in Wuzushan (WZS) and Kuixinglou (KXL) tunnels were determined. WZS tunnel is a major route for diesel vehicles traveling, while KXL tunnel has limited to diesel vehicles. The results showed that the proportions of the different constituents of PM2.5 in the Wuzushan (WZS) tunnel were OC (27.7%), EC (32.1%), elements (13.9%), and water soluble ions (9.2%). Whereas the chemical profile of PM2.5 in the Kuixinglou (KXL) tunnel was OC (17.7%), EC (10.4%), elements (8.90%), and water soluble ions (8.87%). The emission factors (EFs) of PM2.5 and proportions of SO4(2-) and Pb were decreased by vehicle emission standards and fuel quality policy in China, and the higher molecular weight PAHs (4+5+6 rings) were more abundant than the lower molecular weight PAHs (2+3 rings) in the two tunnels. The proportions of 17A(H)-21B(H)-30-Norhopane and 17A(H)-21B(H)-Hopane in the hopane and sterane were not dependent on the vehicles types. In addition, specific composition profiles for PM2.5 from gasoline-fueled vehicles (GV) and diesel-fueled vehicles (DV) emissions were drafted, which indicated that OC (0.974mg·veh(-1)·km(-1)) was the most abundant component in PM2.5, followed by Fe, Cl(-), and Mg for GV. The relative proportions of the different constituents in the PM2.5 for DV were EC (35.9%), OC (27.2%), elements (12.8%), and water soluble ions (11.7%). Both the PM2.5 EFs and EC proportions in DV were higher than those in GV, and the HMW PAHs were the dominant PAHs for both GV and DV. The PM2.5 emissions from the vehicles in Yantai were 581±513tons to 1353±1197tons for GV, and 19,627±2477tons to 23,042±2887tons for DV, respectively.

  3. Crystal structures of four δ-keto esters and a Cambridge Structural Database analysis of cyano-halogen interactions.

    Science.gov (United States)

    Kamal, Kulsoom; Maurya, Hardesh K; Gupta, Atul; Vasudev, Prema G

    2015-10-01

    The revived interest in halogen bonding as a tool in pharmaceutical cocrystals and drug design has indicated that cyano-halogen interactions could play an important role. The crystal structures of four closely related δ-keto esters, which differ only in the substitution at a single C atom (by H, OMe, Cl and Br), are compared, namely ethyl 2-cyano-5-oxo-5-phenyl-3-(piperidin-1-yl)pent-2-enoate, C19H22N2O3, (1), ethyl 2-cyano-5-(4-methoxyphenyl)-5-oxo-3-(piperidin-1-yl)pent-2-enoate, C20H24N2O4, (2), ethyl 5-(4-chlorophenyl)-2-cyano-5-oxo-3-(piperidin-1-yl)pent-2-enoate, C19H21ClN2O3, (3), and the previously published ethyl 5-(4-bromophenyl)-2-cyano-5-oxo-3-(piperidin-1-yl)pent-2-enoate, C19H21BrN2O3, (4) [Maurya, Vasudev & Gupta (2013). RSC Adv. 3, 12955-12962]. The molecular conformations are very similar, while there are differences in the molecular assemblies. Intermolecular C-H...O hydrogen bonds are found to be the primary interactions in the crystal packing and are present in all four structures. The halogenated derivatives have additional aromatic-aromatic interactions and cyano-halogen interactions, further stabilizing the molecular packing. A database analysis of cyano-halogen interactions using the Cambridge Structural Database [CSD; Groom & Allen (2014). Angew. Chem. Int. Ed. 53, 662-671] revealed that about 13% of the organic molecular crystals containing both cyano and halogen groups have cyano-halogen interactions in their packing. Three geometric parameters for the C-X...N[triple-bond]C interaction (X = F, Cl, Br or I), viz. the N...X distance and the C-X...N and C-N...X angles, were analysed. The results indicate that all the short cyano-halogen contacts in the CSD can be classified as halogen bonds, which are directional noncovalent interactions.

  4. Potential redox behaviour on industrial wastes treatment; Evolucion del potencial redox en tratamiento y depuracion industrial de aguas

    Energy Technology Data Exchange (ETDEWEB)

    Marin Galvin, R.; rodriguez Mellado, J. M.; Ruiz Montoya, M.; Jimenez Gamero, C. [Departamento Quimica Fisica y Termodinamica aplicada, Facultad de ciencias, Universidad de Cordoba (Spain)

    1995-12-31

    A study over the behaviour of redox potential in waters and wastewaters under industrial treatment processes has been carried out. In both cases, the potential-time curves obtained were in a logarithmical shape being more strongly distorted when the waters contained more dissolved and suspended compounds. Oxygen fundamentally leads the redox state in wastewaters, although ozone and chlorine almost oxygen lead the redox potential in raw waters intended to drinking water production. In this way, by increasing 210 m V the E{sub H} value of water or maintaining the rH>21.8 it can be industrially sterilized the drinking water. On the other hand, increases of 350 mV in the EH values from wastewaters influent to plant to the treated waters, allowed discarding 450 mg/l of DQO and 9 mg/l of NH{sub 3} from the former. Finally, the exploitation of the Wastewaters Treatment Plant by regulation of the E{sub H} values can suppose a good practice. (Author) 14 refs.

  5. The adsorption and mass-transfer process of cationic red X-GRL dye on natural zeolite.

    Science.gov (United States)

    Tian, Jingjing; Guan, Junfang; Gao, Huimin; Wen, Yafei; Ren, Zijie

    2016-01-01

    The adsorption behavior of natural zeolite was studied in order to determine the adsorption capacity and mass-transfer process of cationic red X-GRL (C(18)H(21)BrN(6)) onto the adsorbent. The adsorption tests to determine both the uptake capacity and the mass-transfer process at equilibrium were performed under batch conditions, which showed rapid uptake in general for the initial 5 min, corresponding to 92% total removal. The equilibrium adsorption capacity value (q(e,cal)) in pseudo-second-order kinetics was 13.51 mg/g at 293 K and the whole adsorption process was governed by physical adsorption with an endothermic, endothermic spontaneous nature. Adsorption tests indicated that the zeolite has great potential as an alternative low-cost material in the treatment of X-GRL drainage. However, the mass-transfer process to determine the rate-controlling steps showed that both film diffusion and pore diffusion were important in controlling the adsorption rate. The adsorption process was governed by film diffusion while pore diffusion was poor because the X-GRL molecules could not penetrate into the zeolite easily. The X-GRL molecules were only adsorbed on the external surface of the zeolite. Hence, to improve the adsorption capacity of natural zeolite further, modification to expand its micropores is necessary.

  6. Power Test of the Ladder IH-RFQ Accelerator at Peking University

    Institute of Scientific and Technical Information of China (English)

    LU Yuan-Rong; CHEN Wei; NIE Yuan-Cun; LIU Ge; GAO Shu-Li; ZENG Hong-Jin; YAN Xue-Qing; CHEN Jia-Er

    2011-01-01

    A 104-MHz ladder interdigital-H radio frequency quadrupole accelerator (T-IH-RFQ) is developed for applying RFQs to heavy ion implantation and accelerator-based mass spectroscopy in recent years at the Institute of Heavy Ion Physics,Peking University.It could accelerate ions with a mass-to-charge ratio of less than 14,from 2.9 ke V/u to 35.7keV/u within a length of 1.1 m.The T-IH-RFQ cavity operating at H21(0) mode was constructed successfully.Based on a well designed rf power feeding system,the cavity was cold measured and tested with high rf power.In the case of cold measurement,the rf properties were obtained using a vector network analyzer with the help of a perturbation capacitor. During a high power test,the inter-electrode voltage was derived from the energy spectrum of x-rays measured by a high purity Ge detector.The results show that the specific shunt impedance of the T-IH-RFQ cavity reaches 178kΩm,which could meet the requirements of beam dynamics design.

  7. Synthesis, crystal structure, interaction with BSA and antibacterial activity of La(III) and Sm(III) complexes with enrofloxacin.

    Science.gov (United States)

    Wang, Yan-Jun; Hu, Rui-Ding; Jiang, Dong-Hua; Zhang, Ping-Hua; Lin, Qiu-Yue; Wang, Yun-Yun

    2011-03-01

    Two new La(III) and Sm(III) complexes with enrofloxacin (HER, 1-cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid, C(19)H(21)FN(3)O(3)), [La(2)(ER)(6)(H(2)O)(2)]·14H(2)O(1) and [Sm(2)(ER)(6)(H(2)O)(2)]·14H(2)O(2) have been synthesized and characterized by elemental analysis, FT-IR, TG-DTG and X-ray single crystal diffraction. Both of the complexes are triclinic system with space group Pī. The structure of the complexes show that each rare earth atom in both complexes was nine-coordinated. Two of the enrofloxacin ions acted as tridentate chelate and bridging ligands, while the others as bidentate chelate ligands. The binding reaction between the complexes and bovine serum albumin (BSA) was studied by UV-vis absorption spectra and fluorescence spectroscopy. The results indicated that the two complexes had a quite strong ability to quench the fluorescence from BSA and the binding reaction was mainly a static quenching process. The binding constants K ( A )/(L·mol(-1)) were 1.46 × 10(5)(1) and 8.59 × 10(6)(2) and one binding site was formed. The synchronous spectroscopy suggested that tryptophan residues were placed in BSA. It was also found that the two complexes exhibited greater antimicrobial activity than enrofloxacin at given concentrations.

  8. Studies of phosphorus Gaussian profile emitter silicon solar cells

    Directory of Open Access Journals (Sweden)

    N. Stem

    2001-01-01

    Full Text Available Considering recent modifications on n-type highly doped silicon parameters, an emitter optimization was made based on one-dimensional models with analytical solutions. In order to get good accuracy, a fifth order approximation has been considered. Two kinds of emitters, homogeneous and non-homogeneous, with phosphorus Gaussian profile emitter solar cells were optimized. According to our results: homogeneous emitter solar cells show their maximum efficiencies (h @ 21.60-21.74%with doping levelsnus = 1x10(19 - 5x10(18 (cm-3 and (1.2-2.0 mum emitter thickness range. Non-homogeneous emitter solar cells provide a slightly higher efficiency (eta = 21.82-21.92%, with Ns = 1x10(20 (cm-3 with 2.0 mum thickness under metal-contacted surface and Ns = 1x10(19 - 5x10(18 (cm-3 with (1.2-2.0 mum thickness range, (sheet resistance range 90-100 W/ under passivated surface. Although non-homogeneous emitter solar cells have a higher efficiency than homogeneous emitter ones, the required technology is more complex and their overall interest for practical applications is questionable.

  9. 苏云金芽孢杆菌科默尔亚种15A3株的cry基因分析及杀虫特性%Characterization of cry Gene and Broad Spectrum Against Lepidopteran of Bacillus thuringiensis subsp. colmeri 15A3

    Institute of Scientific and Technical Information of China (English)

    陈月华; 任改新; 吴卫辉; 王津红; 刘春勇

    2002-01-01

    筛选的苏云金芽孢杆菌野生菌株15A3经鉴定属血清H-21型科默尔亚种.用PCR及RFLP方法对其cryI类基因分析证明其含有crylAa,crylAc,crylCa,crylD,crylI及cry2六种cry基因,其crylA基因N末端1.45kb片段与已发表的序列有差异.表达晶体蛋白质的分子量分别为130,79,70,65,51和45kD.对家蝇致畸实验证明其不含β-外毒素.发酵液对棉铃虫,甜菜夜蛾,小菜蛾及美国白蛾均具较高的毒力.证明野生的苏云金芽孢杆菌资源中也有具国外工程菌所特有的高效杀虫晶体蛋白基因组合的优良菌株.

  10. A Comparative X-ray Diffraction Study and Ab Initio Calculation on RU60358, a New Pyrethroid

    Directory of Open Access Journals (Sweden)

    Gérard Vergoten

    2006-08-01

    Full Text Available The crystal structure of RU60358, C20H21NO3, has been determined using X-raydiffraction to establish the configuration and stereochemistry of the molecule around theC15-C16 triple bond. The compound crystallises in the orthorhombic space group P212121, a= 7.7575, b = 11.3182, c = 21.3529å, V = 1874.80å3 and Z = 4. The structure has beenrefined to a final R = 0.068 for the observed structure factors with I ≥ 3σ (I. The refinedstructure was found to be significantly non planar. A comparative study, using the ab initiocalculations of the structure at B3LYP/6-31G** levels of theory, shows good geometricalagreement with the X-ray diffraction data. Standard deviations between the calculated andexperimental bond values have been shown to be 0.01 å and 0.5° for bond angles.Vibrational wavenumbers were obtained from a normal mode analysis using the ab initiocalculations.

  11. Diurnal fluctuations of cocaine and potential precursors in leaves of Erythroxylum coca.

    Science.gov (United States)

    Johnson, E L

    1993-01-01

    Cocaine is abundant in leaves of Erythroxylum coca var. coca Lam. Consequently, cocaine and two of its early biosynthetic precursors were monitored for 24 h to determine whether they fluctuated diurnally. E. coca was grown under controlled environmental conditions in a growth chamber in soil at pH 3.5. After 17.5 months of growth, leaves not less than 35 days old were harvested every 2 and 4 h for 24 h for arginine, phenylalanine and cocaine content, respectively. The content of cocaine was determined by GC/MS and amino acid content by HPLC. Diurnal fluctuation of cocaine occurred during the 24 h cycle. Cocaine was highest in leaves of E. coca at 8 and 16 h where its content was 7.67 and 9.45 mg.g-1 dry weight, respectively. Arginine and phenylalanine in leaves of E. coca also displayed diurnal rhythmic patterns of fluctuation. The content of arginine declined from hours 6 to 12 and increased to the highest content at 13 h (21.8 mg.g-1 dry weight). Overall, phenylalanine content was lower than arginine, but had two peak periods of accumulation during the 24 h cycle, occurring at 8 and 14 h. The content of phenylalanine in leaves of E. coca during the peak hours was 6.98 and 6.54 mg.g-1 dry weight, respectively.

  12. XMM-Newton and UV Detection of OVIII and Broad HI absorption towards PKS 0558-504: a possible WHIM filament

    CERN Document Server

    Nicastro, F; Fields, D; Conciatore, M L; Zappacosta, L; Elvis, M; Mathur, S; Papadakis, I

    2009-01-01

    We present the first likely X-ray detection associated with Broad HI Ly$\\beta$ (BLB) and Ly$\\alpha$ (BLA) absorbers, consistent with being a WHIM filament. The absorber lies along the line of sight to the nearby ($z=0.1372$) Seyfert 1 galaxy PKS 0558-504. The X-ray absorber is marginally detected in two independent XMM-Newton spectra of PKS 0558-504, with a combined single line statistical significance of 2.8$\\sigma$ (2.7$\\sigma$ and 1.2$\\sigma$ in the two spectra, respectively). When fitted with our self-consistent hybrid-photoionization WHIM models, the combined XMM-{\\em Newton} spectrum is consistent with the presence of an OVIII K$\\alpha$ absorber at $z=(0.117 \\pm 0.001)$, with log$T=6.56_{-0.17}^{+0.19}$ K, and logN$_H=(21.5 \\pm 0.3) (Z/Z_{0.01\\odot})^{-1}$ cm$^{-2}$. The lack of detection of associated OVI in the archival FUSE spectrum of PKS 0558-504, allows us to infer a tighter lower limit on the temperature, of log$T>6.52$ K (at 1$\\sigma$). The statistical sigificance of this single X-ray detection ...

  13. Angiotensin II induces kidney inflammatory injury and fibrosis through binding to myeloid differentiation protein-2 (MD2)

    Science.gov (United States)

    Xu, Zheng; Li, Weixin; Han, Jibo; Zou, Chunpeng; Huang, Weijian; Yu, Weihui; Shan, Xiaoou; Lum, Hazel; Li, Xiaokun; Liang, Guang

    2017-01-01

    Growing evidence indicates that angiotensin II (Ang II), a potent biologically active product of RAS, is a key regulator of renal inflammation and fibrosis. In this study, we tested the hypothesis that Ang II induces renal inflammatory injury and fibrosis through interaction with myeloid differentiation protein-2 (MD2), the accessory protein of toll-like receptor 4 (TLR4) of the immune system. Results indicated that in MD2−/− mice, the Ang II-induced renal fibrosis, inflammation and kidney dysfunction were significantly reduced compared to control Ang II-infused wild-type mice. Similarly, in the presence of small molecule MD2 specific inhibitor L6H21 or siRNA-MD2, the Ang II-induced increases of pro-fibrotic and pro-inflammatory molecules were prevented in tubular NRK-52E cells. MD2 blockade also inhibited activation of NF-κB and ERK. Moreover, MD2 blockade prevented the Ang II-stimulated formation of the MD2/TLR4/MyD88 signaling complex, as well as the increased surface binding of Ang II in NRK-52E cells. In addition, Ang II directly bound recombinant MD2 protein, rather than TLR4 protein. We conclude that MD2 is a significant contributor in the Ang II-induced kidney inflammatory injury in chronic renal diseases. Furthermore, MD2 inhibition could be a new and important therapeutic strategy for preventing progression of chronic renal diseases.

  14. Effect of two human growth hormone receptor antagonists on glomerulosclerosis in streptozotocin-induced diabetic rats

    Institute of Scientific and Technical Information of China (English)

    Wei LI; Shui-xian SHEN; Li-hua ZHU; En-bi WANG; Zeng-can YE; Jun LIN; Li-he GUO; Fei-hong LUO; Xi-hong LIU; Xin FANG

    2004-01-01

    AIM: To explore the feasibility of human growth hormone (hGH) receptor antagonist in the treatment of end-stage diabetic renal complications. METHODS: Two hGH mutants, hGHA1 (Cys-hGH-dell-4, G120R, K168A, E174A,C182S, de1186-191) and hGHA2 (hGH-H21A, G120R, E174A) were expressed in E coli. The IC50 (Mean±SD)values for the mutants for inhibiting 125I-hGH binding to rabbit growth hormone receptor were (65±10) ng for hGHA1, (27±5.6) ng for hGHA2, and (10±0.6) ng for wild type hGH, respectively. RESULTS: After treatment for 12 weeks, the renal histology analysis showed that treatment with hGHA2 at 4 mg/kg body weight daily markedly suppressed glomerulosclerosis in streptozotocin-induced diabetic Sprague-Dawley (SD) rats; hGHA1 at the same dosage slightly increased the renal damage compared with saline; while wild type hGH at 1 U/kg body weight daily severely worsened the glomerulo-sclerosis in diabetic SD rats. CONCLUSION: The data indicated that hGHA2 inhibited the end-stage glomerulosclerosis in diabetic rats, but hGHA1 mildly increased the glomerulosclerosis.

  15. Enhancement of nisin, lysozyme, and monolaurin antimicrobial activities by ethylenediaminetetraacetic acid and lactoferrin.

    Science.gov (United States)

    Branen, Jill K; Davidson, P Michael

    2004-01-01

    A microtiter plate assay was employed to systematically assess the interaction between ethylenediaminetetraacetic acid (EDTA) or lactoferrin and nisin, lysozyme, or monolaurin against strains of Listeria monocytogenes, Escherichia coli, Salmonella enteritidis, and Pseudomonas fluorescens. Low levels of EDTA acted synergistically with nisin and lysozyme against L. monocytogenes but EDTA and monolaurin interacted additively against this microorganism. EDTA synergistically enhanced the activity of nisin, monolaurin, and lysozyme in tryptic soy broth (TSB) against two enterohemorrhagic E. coli strains. In addition, various combinations of nisin, lysozyme, and monolaurin with EDTA were bactericidal to some gram-negative bacteria whereas none of the antimicrobials alone were bactericidal. Lactoferrin alone (2000 microg ml(-1)) did not inhibit any of the bacterial strains, but did enhance nisin activity against both L. monocytogenes strains. Lactoferrin in combination with monolaurin inhibited growth of E. coli O157:H7 but not E. coli O104:H21. While lactoferrin combined with nisin or monolaurin did not completely inhibit growth of the gram-negative bacteria, there was some growth inhibition. All combinations of EDTA or lactoferrin with antimicrobials were less effective in 2% fat UHT milk than in TSB. S. enteritidis and P. fluorescens strains were consistently more resistant to antimicrobial combinations. Resistance may be due to differences in the outer membrane and/or LPS structure.

  16. Prevalence of diarrheagenic Escherichia coli in children with diarrhea in Salvador, Bahia, Brazil

    Directory of Open Access Journals (Sweden)

    Marcia Regina Franzolin

    2005-07-01

    Full Text Available We report the frequency of the different diarrheagenic Escherichia coli (DEC categories isolated from children with acute endemic diarrhea in Salvador, Bahia. The E. coli isolates were investigated by colony blot hibridization whit the following genes probes: eae, EAF, bfpA, Stx1, Stx2, ST-Ih, ST-Ip, LT-I, LT-II, INV, and EAEC, as virulence markers to distinguish typical and atypical EPEC, EHEC/STEC, ETEC, EIEC, and EAEC. Seven of the eight categories of DEC were detected. The most frequently isolated was atypical EPEC (10.1% followed by ETEC (7.5%, and EAEC (4.2%. EHEC, STEC, EIEC, and typical EPEC were each detected once. The strains of ETEC, EAEC, and atypical EPEC belonged to a wide variety of serotypes. The serotypes of the others categories were O26:H11 (EHEC, O21:H21 (STEC, O142:H34 (typical EPEC, and O?H55 (EIEC. We also present the clinical manifestations and other pathogenic species observed in children with DEC. This is the first report of EHEC and STEC in Salvador, and one of the first in Brazil.

  17. Microbial production of a biofuel (acetone-butanol-ethanol) in a continuous bioreactor: impact of bleed and simultaneous product removal.

    Science.gov (United States)

    Ezeji, Thaddeus Chukwuemeka; Qureshi, Nasib; Blaschek, Hans Peter

    2013-01-01

    Acetone butanol ethanol (ABE) was produced in an integrated continuous one-stage fermentation and gas stripping product recovery system using Clostridium beijerinckii BA101 and fermentation gases (CO(2) and H(2)). In this system, the bioreactor was fed with a concentrated sugar solution (250-500 g L(-1) glucose). The bioreactor was bled semi-continuously to avoid accumulation of inhibitory chemicals and products. The continuous system was operated for 504 h (21 days) after which the fermentation was intentionally terminated. The bioreactor produced 461.3 g ABE from 1,125.0 g total sugar in 1 L culture volume as compared to a control batch process in which 18.4 g ABE was produced from 47.3 g sugar. These results demonstrate that ABE fermentation can be operated in an integrated continuous one-stage fermentation and product recovery system for a long period of time, if butanol and other microbial metabolites in the bioreactor are kept below threshold of toxicity.

  18. Synthesis and Crystal Structure of a [Cu(HTren)Cl2]ClO4·H2O Complex (Tren = Tris(2-aminoethyl)amine)

    Institute of Scientific and Technical Information of China (English)

    NIU De-Zhong; MA Heng-Jun; GAO Feng; LU Zai-Sheng; CHEN Jiu-Tong

    2006-01-01

    The title complex [Cu(HTren)Cl2]ClO4·H2O (Tren = tris(2-aminoethyl)amine) was crystal (CuC6H21Cl3N4O5) is of triclinic, space group P-1, with a = 8.2689(2), b = 8.4503(3), c=11.6801(4)(A), a = 96.9350(10), β= 108.2440(10), γ = 90.7550(10)°, V= 768.32(4)(A)3, Z= 2, Mr=399.16, Dc= 1.725 g/cm3,μ= 1.962 mm-1, F(000) = 410, T= 293(2) K, the final R = 0.0479 and wR = 0.1339 for 2659 observed reflections with I > 2σ(I). X-ray single-crystal structure analysis reveals that the copper(Ⅱ) atom adopts a slightly distorted square-pyramidal geometry. The distances between Cu and N atoms (N(1), N(2), N(3)) range from 1.975(4) to 2.116(3)(A). The bond lengths of Cu-Cl(1) and Cu-Cl(2) are 2.309(10) and 2.591(10) (A), respectively. The whole crystal presents a three-dimensional network structure by hydrogen bonds.

  19. Crystal structure of {(S)-1-phenyl-N,N-bis­[(pyridin-2-yl)meth­yl]ethanamine-κ3 N,N′,N′′}bis­(thio­cyanato-κN)zinc from synchrotron data

    Science.gov (United States)

    Lee, Dong Won; Shin, Jong Won

    2017-01-01

    The title ZnII complex, [Zn(NCS)2(C20H21N3)], has been characterized by synchrotron single-crystal diffraction and FT–IR spectroscopy. The central ZnII ion has a distorted square-pyramidal coordination geometry, with three N atoms of the chiral (S) 1-phenyl-N,N-bis­[(pyridin-2-yl)meth­yl]ethanamine (S-ppme) ligand and one N atom of a thio­cyanate anion in the equatorial plane, and one N atom of another thio­cyanate anion at the apical position. The average Zn—NS-ppme and Zn—NNCS bond lengths are 2.183 (2) and 1.986 (2) Å, respectively. In the crystal, inter­molecular C—H⋯S hydrogen bonds and a face-to-face π–π inter­action [centroid–centroid distance = 3.482 (1) Å] link the mol­ecules and give rise to a supra­molecular sheet structure parallel to the ac plane. PMID:28083125

  20. [μ-Bis(diphenylarsinomethane-1:2κ2As:As′]nonacarbonyl-1κ3C,2κ3C,3κ3C-[tris(4-methylphenylphosphine-3κP]-triangulo-triruthenium(0

    Directory of Open Access Journals (Sweden)

    Omar bin Shawkataly

    2010-01-01

    Full Text Available In the title triangulo-triruthenium compound, [Ru3(C25H22As2(C21H21P(CO9], the bis(diphenylarsinomethane ligand bridges a Ru—Ru bond and the monodentate phosphine ligand bonds to the third Ru atom. Both the phosphine and arsine ligands are equatorial with respect to the Ru3 triangle. Additionally, each Ru atom carries one equatorial and two axial terminal carbonyl ligands. The three phenyl rings of the phosphine make dihedral angles of 86.89 (19, 82.1 (2 and 63.0 (2° with each other. The dihedral angles between the two phenyl rings are 73.8 (2 and 82.2 (3° for the two diphenylarsino groups. An intramolecular C—H...O hydrogen bond stabilizes the molecular structure. In the crystal packing, molecules are linked into chains down the b axis via intermolecular C—H...O hydrogen bonds.

  1. Synthesis, Crystal Structure and Magnetic Properties of a New Zn(Ⅱ)-Nitronyl Nitroxide Complex

    Institute of Scientific and Technical Information of China (English)

    JIANG Kai; YANG Rui-Hua; WANG Li-Ya; WANG Yu-Fang

    2008-01-01

    A new complex [Zn(NIT-1'-MeBzIm)Cl2(H2O)] (NIT-1'-MeBzIm = 2-{2'-[(1'-methyl)benzimidazolyl]}-4,4,5,5-tetramethylimidazoline-l-oxyl-3-oxide) has been prepared and structurally characterized by X-ray diffraction method. Crystal data: monoclinic, space group P21/n, Z = 4, C15H21Cl2N4O3Zn, Mr = 441.63, a = 7.2225(10), b = 30.849(4), c = 8.8758(13) (A), β= 103.904(2)°, V = 1919.6(5) A3, Dc = 1.528 g/cm3, μ(MoKα) = 1.579 mm-1, F(000) = 908, R = 0.0436 and wR = 0.1029 for 2456 observed reflections with Ⅰ> 2σ(Ⅰ). X-ray analysis reveals that the Zn(Ⅱ) ion is four-coordinated with a distorted tetrahedron. There also exist H-bonds, π-π piling interactions and weak intermolecular contacts between the NO groups which form a mutual stagger 3-D network configuration. Magnetic investigation reveals that there exists intermolecular antiferro- and ferromagnetic interactions in the title complex.

  2. catena-Poly[2,2′,2′′-nitrilotris(ethanaminium [tri-μ-oxido-tris[dioxidovanadate(V

    Directory of Open Access Journals (Sweden)

    Kelvin B. Chang

    2013-11-01

    Full Text Available The title compound, {(C6H21N4[V3O9]·H2O}n, crystallizes as a salt with [trenH3]3+ cations [tren is tris(2-aminoethylamine], and one-dimensional anionic {[VVO3]−}n (metavanadate chains along the c-axis direction. Three crystallographically distinct VV sites and one occluded water molecule are present for every [trenH3]3+ cation in the unit cell. The {[VVO3]−}n chains are composed of vertex-sharing [VO4] tetrahedra and have a repeat unit of six tetrahedra. Each tetrahedron in the chain contains two terminal and two μ2-bridging oxide ligands. The [trenH3]3+ cations, {[VVO3]−}n anions and occluded water molecules participate in an extensive three-dimensonal hydrogen-bonding network. The three terminal ammonium sites of the [trenH3]3+ cations each form strong N—H...O hydrogen bonds to terminal oxide ligands on the {[VVO3]−}n chain. Each occluded water molecule also donates two O—H...O hydrogen bonds to the terminal oxide ligands.

  3. Three closely related dibenzazepine carboxylic acids: hydrogen-bonded aggregation in one, two and three dimensions.

    Science.gov (United States)

    Sanabría, Carlos M; Palma, Alirio; Cobo, Justo; Glidewell, Christopher

    2014-03-01

    In the structure of (6R*,11R*)-5-acetyl-11-ethyl-6,11-dihydro-5H-dibenzo[b,e]azepine-6-carboxylic acid, C19H19NO3, (I), the molecules are linked into sheets by a combination of O-H...O and C-H...O hydrogen bonds; in the structure of the monomethyl analogue (6RS,11SR)-5-acetyl-11-ethyl-2-methyl-6,11-dihydro-5H-dibenzo[b,e]azepine-6-carboxylic acid, C20H21NO3, (II), the molecules are linked into simple C(7) chains by O-H...O hydrogen bonds; and in the structure of the dimethyl analogue (6RS,11SR)-5-acetyl-11-ethyl-1,3-dimethyl-6,11-dihydro-5H-dibenzo[b,e]azepine-6-carboxylic acid, C21H23NO3, (III), a combination of O-H...O, C-H...O and C-H...π(arene) hydrogen bonds links the molecules into a three-dimensional framework structure. None of these structures exhibits the R2(2)(8) dimer motif characteristic of simple carboxylic acids.

  4. High resolution mapping of Dense spike-ar (dsp.ar) to the genetic centromere of barley chromosome 7H.

    Science.gov (United States)

    Shahinnia, Fahimeh; Druka, Arnis; Franckowiak, Jerome; Morgante, Michele; Waugh, Robbie; Stein, Nils

    2012-02-01

    Spike density in barley is under the control of several major genes, as documented previously by genetic analysis of a number of morphological mutants. One such class of mutants affects the rachis internode length leading to dense or compact spikes and the underlying genes were designated dense spike (dsp). We previously delimited two introgressed genomic segments on chromosome 3H (21 SNP loci, 35.5 cM) and 7H (17 SNP loci, 20.34 cM) in BW265, a BC(7)F(3) nearly isogenic line (NIL) of cv. Bowman as potentially containing the dense spike mutant locus dsp.ar, by genotyping 1,536 single nucleotide polymorphism (SNP) markers in both BW265 and its recurrent parent. Here, the gene was allocated by high-resolution bi-parental mapping to a 0.37 cM interval between markers SC57808 (Hv_SPL14)-CAPSK06413 residing on the short and long arm at the genetic centromere of chromosome 7H, respectively. This region putatively contains more than 800 genes as deduced by comparison with the collinear regions of barley, rice, sorghum and Brachypodium, Classical map-based isolation of the gene dsp.ar thus will be complicated due to the infavorable relationship of genetic to physical distances at the target locus.

  5. Limits on the Size and Orbit Distribution of Main Belt Comets

    CERN Document Server

    Sonnett, S; Jedicke, R; Masiero, J

    2011-01-01

    The seven known main belt comets (MBCs) have orbital characteristics of main belt asteroids yet exhibit dust ejection like comets. In order to constrain their physical and orbital properties we searched the Thousand Asteroid Light Curve Survey (TALCS; Masiero et al. 2009) for additional candidates using two diagnostics: tail and coma detection. This was the most sensitive MBC survey effort to date, extending the search from MBCs with H~18 (D~1 km) to H~21 (D~150 m). We fit each of the 924 TALCS objects to a PSF model incorporating both a coma and nuclear component to measure the fractional contribution of the coma to the total surface brightness. We determined the significance of the coma detection using the same algorithm on a sample of comparable null detections. We did not identify any MBC candidates with this technique to a sensitivity limit on the order of cometary mass loss rate of about 0.1 kg/s. Our tail detection algorithm identified statistically significant flux in a segmented annulus around the ca...

  6. Distorted octahedral environments in tricarbonylrhenium(I) complexes of 5-[2-(2,4,6-trimethylphenyl)diazen-1-yl]quinolin-8-olate and 5,7-bis[2-(2-methylphenyl)diazen-1-yl]quinolin-8-olate.

    Science.gov (United States)

    Schutte-Smith, Marietjie; Muller, Theunis J; Visser, Hendrik G; Roodt, Andreas

    2013-12-15

    The Re(I) centres of two Re(I)-tricarbonyl complexes, viz. tricarbonyl(pyridine-κN){5-[2-(2,4,6-trimethylphenyl)diazen-1-yl]quinolin-8-olato-κ(2)N(1),O}rhenium(I), [Re(C23H21N4O)(CO)3], (I), and {5,7-bis[2-(2-methylphenyl)diazen-1-yl]quinolin-8-olato-κ(2)N(1),O}tricarbonyl(pyridine-κN)rhenium(I), [Re(C28H23N6O)(CO)3], (II), are facially surrounded by three carbonyl ligands, a pyridine ligand and either a 5-[2-(2,4,6-trimethylphenyl)diazen-1-yl]quinolin-8-olate [in (I)] or a 5,7-bis[2-(2-methylphenyl)diazen-1-yl]quinolin-8-olate [in (II)] ligand, in a slightly distorted octahedral environment. The crystal structure of (I) is stabilized by two intermolecular C-H···O interactions and that of (II) is stabilized by three intermolecular C-H···O hydrogen-bonding interactions.

  7. Shape Memory Polymer Composites of Poly(styrene-b-butadiene-b-styrene Copolymer/Liner Low Density Polyethylene/Fe3O4 Nanoparticles for Remote Activation

    Directory of Open Access Journals (Sweden)

    Yongkun Wang

    2016-11-01

    Full Text Available Magnetically sensitive shape memory poly(styrene-b-butadiene-b-styrene copolymer (SBS/liner low density polyethylene (LLDPE composites filled with various contents of Fe3O4 nanoparticles were prepared. The influence of the Fe3O4 nanoparticles content on the thermal properties, mechanical properties, fracture morphology, magnetic behavior, and shape memory effect of SBS/LLDPE/Fe3O4 composites was systematically studied in this paper. The results indicated that homogeneously dispersed Fe3O4 nanoparticles ensured the uniform heat generation and transfer in the alternating magnetic field, and endowed the SBS/LLDPE/Fe3O4 composites with an excellent magnetically responsive shape memory effect. When the shape memory composites were in the alternating magnetic field (f = 60 kHz, H = 21.21 kA·m−1, the best shape recovery ratio reached 99%, the shape retention ratio reached 99.4%, and the shape recovery speed increased significantly with the increment of Fe3O4 nanoparticles. It is anticipated that tagging products with this novel shape memory composite is helpful for the purpose of an intravascular delivery system in Micro-Electro-Mechanical System (MEMS devices.

  8. Detection of Shiga toxin-producing Escherichia coli in meat marketed in Casablanca (Morocco).

    Science.gov (United States)

    Badri, S; Fassouane, A; Filliol, I; Hassar, M; Cohen, N

    2011-03-01

    The contamination of meat and meat products with Shiga toxin-producing O157:H7 and non-O157 Escherichia coli (STEC), obtained from markets in Casablanca, Morocco, was investigated. A total of 460 meat and meat products were sampled between March 2004 and July 2006 analysed and 176 strains of E. coli were isolated from these samples. The presence of the stx1, stx2, eae and ehxA genes, recognized as major virulence factors of STEC, was tested in E. coli isolates by polymerase chain reaction (PCR). STEC was detected in 4 (0.9%) samples. The result of serotyping by molecular method showed that two of these STEC isolates corresponded to the serotype O157:H7. The others Shiga toxin-producing E. coli non-O157 corresponded to O6:H21 and O76:H19. The presence of O157:H7 and non-O157 STEC in meat and meat products marketed in Casablanca, Morocco, emphasizes the importance of implementing the Hazard Analysis and Critical Control Point (HACCP) system, as well as the need for implementing, evaluating, and validating antimicrobial interventions to reduce the presence of potential pathogenic microorganisms.

  9. Synthesis and Structure Characterization of Mn2(CO)6(μ-S2CPiPr3)

    Institute of Scientific and Technical Information of China (English)

    马永强; 陈晓; 李靖; 谢庆兰; 王宏根

    2003-01-01

    The homobinuclear compound Mn2(CO)6(u-S2CPiPr3) has been prepared by the reaction of BrMn(CO)3(u-S2CPiPr3) with NaMn(CO)5 in refluxing THF, and its structure was determined by single-crystal X-ray diffraction. Crystallographic data: C16H21Mn2O6PS2, Mr = 514.30, triclinic, space group Pīwith a = 9.293(3), b = 9.443(3), c = 12.977(4) A。, a = 83.633(5), b= 83.719(5), c= 73.399(5) V = 1081.1(6) A。3, Z = 2, Dc = 1.580 g/cm3, a = 1.463 mm-1, F(000) = 524, the final R = 0.0330 and wR = 0.0729 for 2945 observed reflections with I > 2o(I). The crystal structure determination shows that the ligand can be described as a η2(S, S') chelate to one manganese and a η3(S, C, S') pseudoallyl to the other manganese bridging the Mn-Mn bond asymmetrically.

  10. Crystal structures of (E-3-(furan-2-yl-2-phenyl-N-tosylacrylamide and (E-3-phenyl-2-(m-tolyl-N-tosylacrylamide

    Directory of Open Access Journals (Sweden)

    Dong Cheng

    2016-06-01

    Full Text Available In the title N-tosylacrylamide compounds, C20H17NO4S, (I, and C23H21NO3S, (II, the conformation about the C=C bond is E. The acrylamide groups, [–NH—C(=O—C=C–], are almost planar, with the N—C—C=C torsion angle being −170.18 (14° in (I and −168.01 (17° in (II. In (I, the furan, phenyl and 4-methylbenzene rings are inclined to the acrylamide mean plane by 26.47 (11, 69.01 (8 and 82.49 (9°, respectively. In (II, the phenyl, 3-methylbenzene and 4-methylbenzene rings are inclined to the acrylamide mean plane by 11.61 (10, 78.44 (10 and 78.24 (10°, respectively. There is an intramolecular C—H...π interaction present in compound (II. In the crystals of both compounds, molecules are linked by pairs of N—H...O hydrogen bonds, forming inversion dimers with an R22(8 ring motif. In (I, the dimers are reinforced by C—H...O hydrogen bonds and linked by C—H...π interactions, forming chains along [011]. In the crystal of (II, the dimers are linked via C—H...O hydrogen bonds, forming chains along [100]. The chains are further linked by C—H...π interactions, forming layers parallel to (010.

  11. Volatilization of arsenic from polluted soil by Pseudomonas putida engineered for expression of the arsM Arsenic(III) S-adenosine methyltransferase gene.

    Science.gov (United States)

    Chen, Jian; Sun, Guo-Xin; Wang, Xiao-Xue; Lorenzo, Víctor de; Rosen, Barry P; Zhu, Yong-Guan

    2014-09-02

    Even though arsenic is one of the most widespread environmental carcinogens, methods of remediation are still limited. In this report we demonstrate that a strain of Pseudomonas putida KT2440 endowed with chromosomal expression of the arsM gene encoding the As(III) S-adenosylmethionine (SAM) methyltransfase from Rhodopseudomonas palustris to remove arsenic from contaminated soil. We genetically engineered the P. putida KT2440 with stable expression of an arsM-gfp fusion gene (GE P. putida), which was inserted into the bacterial chromosome. GE P. putida showed high arsenic methylation and volatilization activity. When exposed to 25 μM arsenite or arsenate overnight, most inorganic arsenic was methylated to the less toxic methylated arsenicals methylarsenate (MAs(V)), dimethylarsenate (DMAs(V)) and trimethylarsine oxide (TMAs(V)O). Of total added arsenic, the species were about 62 ± 2.2% DMAs(V), 25 ± 1.4% MAs(V) and 10 ± 1.2% TMAs(V)O. Volatilized arsenicals were trapped, and the predominant species were dimethylarsine (Me2AsH) (21 ± 1.0%) and trimethylarsine (TMAs(III)) (10 ± 1.2%). At later times, more DMAs(V) and volatile species were produced. Volatilization of Me2AsH and TMAs(III) from contaminated soil is thus possible with this genetically engineered bacterium and could be instrumental as an agent for reducing the inorganic arsenic content of soil and agricultural products.

  12. Drug: D10006 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D10006 Drug Eplivanserin (USAN/INN) C19H21FN2O2 328.1587 328.3806 D10006.gif Treatm...tonin 5-HT2A-receptor [HSA:3356] [KO:K04157] Eplivanserin D10006 Eplivanserin (USAN/INN) CAS: 130579-75-8 Pu...bChem: 135626727 LigandBox: D10006 ATOM 24 1 C8x C 19.3200 -22.2600 2 C8x C 19.3200 -23.6600 3 C8x C 20.5100... -24.3600 4 C8x C 21.7700 -23.6600 5 C8y C 21.7700 -22.2600 6 C8y C 20.5100 -21.5...600 7 X F 22.9600 -21.5600 8 C2c C 20.5100 -20.1600 9 C2b C 19.3200 -19.4600 10 N2b N 21.7000 -19.4600 11 C2

  13. Synthesis, Properties and Crystal Structure of a Novel Coordinated Polymer: {(H2en)(H3O)[(BiPb(C2O4)4(H2O)2)]·2(H2O)}n

    Institute of Scientific and Technical Information of China (English)

    GUO Wen-Jun; ZHANG Han-Hui; HUANG Chang-Cang; SUN Rui-Qing; CHEN Yi-Ping; CAO Yan-Ning

    2005-01-01

    A novel oxalate compound {(H2en)(H3O)[BiPb(C2O4)4(H2O)2]·2(H2O)}n 1 (en = ethylenediamine) containing lead and bismuth has been synthesized by hydrothermal methods, and structurally characterized by X-ray single-crystal diffraction. It crystallizes in monoclinic, space group P21/c with a = 11.6160(1), b = 12.7426(1), c = 15.5683(5) (A), β = 108.442(4)°, BiPbC10N2O21H21, Mr = 921.46, V = 2186.0(4) (A)3, Z = 4, Dc = 2.800 g/cm3, F(000) = 1712 and μ(MoKα) = 15.837 mm-1. The final R = 0.0502 and wR = 0.1261 for 3391 observed reflections with I > 2(σI). The title com- pound consists of 2-D polyanions and protonized organic amine cations, and they are combined to each other by static attractive force and H-bonds to form the so-called organic-inorganic hybrid material.

  14. Efectos de extinción en curvas de rotación de galaxias espirales

    Science.gov (United States)

    Valotto, C.; Giovanelli, R.

    Observations show that the slope of the inner part of the Hα/[NII] rotation curves of disk galaxies is depressed by extinction: at fixed luminosity, the observed slope is in fact seen to depend on the disk inclination to the line of sight. Using a simple extinction model, we are able to reproduce well the observed trends. The model assumes an exponential distribution, both in the radial and z directions, identical for star-forming regions and dust. Fits to the data are optimized by varying the scale height and scale length of absorbers, as well as the disk's central optical depth τo, as seen face-on. The observations indicate that disk central opacity increases with total luminosity. Model fits for the most luminous galaxies (brighter than M-5 log h=-21.4 in the I band) yield τo ≃ 3.5+4.0-2.0, near λ=0.66 μm. The large uncertainty on the inferred value of τo is due to the poorly known characteristics of the distribution of absorbers in the disk, as well as to the likelihood of strong departures from an exponential radial distribution near the galaxy centers.

  15. Crystal structure of (4-methoxyphenyl[(4-methoxyphenylphosphonato]dioxidophosphate(1− 2-amino-6-benzyl-3-ethoxycarbonyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-6-ium

    Directory of Open Access Journals (Sweden)

    Joel T. Mague

    2015-12-01

    Full Text Available The asymmetric unit of the title molecular salt, C17H21N2O2S+·C14H15O7P2−, comprises two cations and two anions. Each cation features an intramolecular N—H...O hydrogen bond, which closes an S(6 ring; in each case the hydropyridine ring adopts a half-chair conformation. In the anions, the dihedral angles between the aromatic rings are 64.1 (2 and 54.9 (2°. In each case, the diphosphate groups are close to eclipsed [C—P...P—C pseudo-torsion angles = 11.6 (2 and −19.3 (2°]. One of the methoxy groups in each anion is disordered over two orientations in a 0.539 (18:0.461 (18 ratio in one anion and 0.82 (2:0.18 (2 in the other. In the crystal, O—H...O and N—H...O hydrogen bonds link the components into [100] chains. Numerous C—H...O interactions cross-link the chains into a three-dimensional network.

  16. Hypoglycemic and anti-hyperglycemic study of Ocimum tenuiflorum L. leaves extract in normal and streptozotocin-induced diabetic rats

    Institute of Scientific and Technical Information of China (English)

    Leila Mousavi; Rabeta Mohd Salleh; Vikneswaran Murugaiyah; Mohd Zaini Asmawi

    2016-01-01

    Objective: To investigate the antidiabetic activity of Ocimum tenuiflorum L. (O. tenui-florum) leaves used in the traditional medicine management of diabetes in Malaysia. Methods: O. tenuiflorum leaves were extracted sequentially with hexane, chloroform, ethyl acetate, methanol, and water. The extracts were evaluated in terms of antidiabetic activity by using acute, subcutaneous glucose tolerance, and sub-chronic tests in streptozotocin-induced diabetic rats. The extracts were also subjected to phytochemical analyses. Results: With an acute dose (1 g/kg), the methanol extracts showed significant reduction (31%) in fasting blood glucose (FBG) of the streptozotocin-induced diabetic rats. The FBG-decreasing effect of ethyl acetate extract was more rapid than that of the other extracts;the decreasing rates were 20%after 2 h, 21%after 3 h, and 8%after 5 and 7 h. After 7 h (31%), the effect of methanol extract on FBG was significantly lower than that of metformin. In the subcutaneous glucose tolerance test, only methanol and hexane extracts showed the similarity of metformin in diabetic rats. After 14 days, the effects of these extracts were similar to those of metformin (63.33%). The total flavonoid and phenolic contents of extracts decreased as the polarity of the extraction solvent increased. Conclusions: The results obtained provide support for a possible use of O. tenuiflorum leaves in managing hyperglycemia and preventing the complications associated with it in type 2 diabetic.

  17. Chemoprevention of Colonic Aberrant Crypt Foci by Novel Schiff Based Dichlorido(4-Methoxy-2-{[2-(Piperazin-4-Ium-1-Yl)Ethyl]Iminomethyl}Phenolate)Cd Complex in Azoxymethane-Induced Colorectal Cancer in Rats.

    Science.gov (United States)

    Hajrezaie, Maryam; Shams, Keivan; Moghadamtousi, Soheil Zorofchian; Karimian, Hamed; Hassandarvish, Pouya; Emtyazjoo, Mozhgan; Zahedifard, Maryam; Majid, Nazia Abdul; Mohd Ali, Hapipah; Abdulla, Mahmood Ameen

    2015-07-23

    Schiff-based complexes as a source of cancer chemotherapeutic compounds have been subjected to the variety of anticancer studies. The in-vitro analysis confirmed the CdCl2(C14H21N3O2) complex possess cytotoxicity and apoptosis induction properties in colon cancer cells, so lead to investigate the inhibitory efficiency of the compound on colonic aberrant crypt foci (ACF). Five groups of adult male rats were used in this study: Vehicle, cancer control, positive control groups and the groups treated with 25 and 50 mg/kg of complex for 10 weeks. The rats in vehicle group were injected subcutaneously with 15 mg/kg of sterile normal saline once a week for 2 weeks and orally administered with 5% Tween-20 (5 ml/kg) for 10 weeks, other groups were injected subcutaneously with 15 mg/kg azoxymethane once a week for 2 weeks. The rats in positive groups were injected intra-peritoneally with 35 mg/kg 5-Flourouracil four times in a month. Administration of the complex suppressed total colonic ACF formation up to 73.4% (P < 0.05). The results also showed that treatment with the complex significantly reduced the level of malondialdehyde while increasing superoxide dismutase and catalase activities. Furthermore, the down-regulation of PCNA and Bcl2 and the up-regulation of Bax was confirmed by immunohistochemical staining.

  18. Hydrocarbon geochemistry of the Puget Sound region. II. Sedimentary diterpenoid, steroid and triterpenoid hydrocarbons

    Energy Technology Data Exchange (ETDEWEB)

    Barrick, R.C.; Hedges, J.I.

    1981-03-01

    Cyclic components of the aliphatic hydrocarbon mixtures extracted from Puget Sound sediment cores include a suite of C/sub 19/ and C/sub 20/ diterpenoid hydrocarbons of which fichtelite, sandaracopimaradiene, and isopimaradiene have been identified. Although apparently also derived from vascular plants, these diterpenoid hydrocarbons have relative abundances distinctly different from the co-existing plant wax n-alkane suite. Five C/sub 27/, C/sub 28/ and C/sub 29/ diasteranes and four C/sub 29/, C/sub 30/ and C/sub 31/ 17..cap alpha..(H), 21..beta..(H) hopanes occur in relatively constant proportion as components of a highly weathered fossil hydrocarbon assemblage. These chromatographically resolved cycloalkanes, along with the strongly covarying unresolved complex mixture, have been introduced to Puget Sound sediments from adjacent urban centres at increasing levels over the last 100 yr in the absence of any major oil spill. Naturally-occurring triterpenoid hydrocarbons, including hop-22(29)-ene (diploptene), are also present. A new group of C/sub 30/ polyenes has been detected which contains compounds apparently structurally related to a co-existing bicyclic C/sub 25/ diene and to C/sub 20/ and C/sub 25/ acyclic multibranched hydrocarbons described in a previous paper (Barrick et al., 1980).

  19. Hydrocarbon geochemistry of the Puget Sound region - II. Sedimentary diterpenoid, steroid and triterpenoid hydrocarbons

    Science.gov (United States)

    Barrick, Robert C.; Hedges, John I.

    1981-03-01

    Cyclic components of the 'aliphatic' hydrocarbon mixtures extracted from Puget Sound sediment cores include a suite of C 19 and C 20 diterpenoid hydrocarbons of which fichtelite. sandaracopimaradiene, and isopimaradiene have been identified. Although apparently also derived from vascular plants, these diterpenoid hydrocarbons have relative abundances distinctly different from the co-existing plant wax n-alkane suite. Five C 27, C 28 and C 29 diasteranes and four C 29, C 30 and C 31 17α(H), 21β(H) hopanes occur in relatively constant proportion as components of a highly weathered fossil hydrocarbon assemblage. These chromatographically resolved cycloalkanes. along with the strongly covarying unresolved complex mixture, have been introduced to Puget Sound sediments from adjacent urban centres at increasing levels over the last 100 yr in the absence of any major oil spill. Naturally-occurring triterpenoid hydrocarbons, including hop-22(29)-ene (diploptene), are also present. A new group of C 30 polyenes has been detected which contains compounds apparently structurally related to a co-existing bicyclic C 25 diene and to C 20 and C 25 acyclic multibranched hydrocarbons described in a previous paper ( BARRICK et al., 1980).

  20. The Multiwavelength Survey by Yale-Chile (MUSYC): Deep Near-Infrared Imaging and the Selection of Distant Galaxies

    CERN Document Server

    Quadri, R; van Dokkum, P; Gawiser, E; Franx, M; Lira, P; Rudnick, G; Urry, C M; Maza, J; Kriek, M; Barrientos, L F; Blanc, G; Castander, F J; Christlein, D; Coppi, P S; Hall, P B; Herrera, D; Infante, L; Taylor, E N; Treister, E; Willis, J P; Quadri, Ryan; Marchesini, Danilo; Dokkum, Pieter van; Gawiser, Eric; Franx, Marijn; Lira, Paulina; Rudnick, Gregory; Maza, Jose; Kriek, Mariska; Blanc, Guillermo; Castander, Francisco J.; Christlein, Daniel; Coppi, Paolo S.; Hall, Patrick B.; Herrera, David; Infante, Leopoldo; Taylor, Edward N.; Treister, Ezequiel; Willis, Jon P.

    2006-01-01

    We present deep near-infrared JHK imaging of four 10'x10' fields. The observations were carried out as part of the Multiwavelength Survey by Yale-Chile (MUSYC) with ISPI on the CTIO 4m telescope. The typical point source limiting depths are J~22.5, H~21.5, and K~21 (5sigma; Vega). The effective seeing in the final images is ~1.0". We combine these data with MUSYC UBVRIz imaging to create K-selected catalogs that are unique for their uniform size, depth, filter coverage, and image quality. We investigate the rest-frame optical colors and photometric redshifts of galaxies that are selected using common color selection techniques, including distant red galaxies (DRGs), star-forming and passive BzKs, and the rest-frame UV-selected BM, BX, and Lyman break galaxies (LBGs). These techniques are effective at isolating large samples of high redshift galaxies, but none provide complete or uniform samples across the targeted redshift ranges. The DRG and BM/BX/LBG criteria identify populations of red and blue galaxies, r...

  1. Evaluation of biodiesel as bioremediation agent for the treatment of the shore affected by the heavy oil spill of the Prestige.

    Science.gov (United States)

    Fernández-Alvarez, P; Vila, J; Garrido, J M; Grifoll, M; Feijoo, G; Lema, J M

    2007-08-25

    The efficiency of different bioremediation products (nutrients, microorganisms and biodiesel) was tested using tiles located in both the supra-littoral and intertidal zones of a beach that was affected by the heavy oil spill of the Prestige. Neither nutrients nor microorganisms meant an improvement with respect to the natural processes. The addition of biodiesel improved the appearance of the treated tiles and apparently accelerated the degradation of the aliphatic and aromatic fractions of the residual fuel oil. Nevertheless, PAHs degradation was similar and very high in all the treatments (80-85% after 60 days). On the other hand, the evolution with time of the amount of vanadium was similar to that of 17alpha(H),21beta(H)-hopane, so it was concluded that vanadium could also be used to estimate the extent of oil degradation in the field. These results also suggested that the residual fuel oil mineralization was very low throughout 1 year in all the treatments. Moreover, the increase of the oxygen content of the residual oil from around 1% till 4-8% indicated that the partial oxidation of hydrocarbons took place, and that the hydrocarbon oxidation products accumulated in the polar fractions. In general, the results pointed out that bioremediation techniques were not suitable for the recovery of shores affected by heavy oil spills.

  2. Asteroid 2013 ND15: Trojan companion to Venus, PHA to the Earth

    CERN Document Server

    Marcos, C de la Fuente

    2014-01-01

    Venus has three known co-orbitals: (322756) 2001 CK32, 2002 VE68 and 2012 XE133. The first two have absolute magnitudes 18 < H < 21. The third one, significantly smaller at H = 23.4 mag, is a recent discovery that signals the probable presence of many other similar objects: small transient companions to Venus that are also potentially hazardous asteroids (PHAs). Here, we study the dynamical evolution of the recently discovered asteroid 2013 ND15. At H = 24.1 mag, this minor body is yet another small Venus co-orbital and PHA, currently close to the Lagrangian point L4 and following the most eccentric path found so far for objects in this group. Due to its high eccentricity (0.6), its dynamics is different from that of the other three known Venus co-orbitals even if they all are near-Earth objects (NEOs). A Monte Carlo simulation that uses the orbital data and discovery circumstances of the four objects as proxies to estimate the current size of this population, indicates that the number of high-eccentric...

  3. Determination of arterial wall shear stress

    Institute of Scientific and Technical Information of China (English)

    LIU; Zhaorong

    2001-01-01

    [1]Langille, B. L., 7Donnell, F., Reductions in arterial diameter produced by chronic decreases in blood flow are endothelium-dependent, Science, 1986, 231: 405—407.[2]Langer, R., Vacanti, J. P., Tissue engineering, Science, 1993, 260: 920—926.[3]Kamiya, A., Togawa, T., Adaptive regulation of wall shear stress to flow change in the canine carotid artery, Am. J. Physiol. (Heart Circ. Physiol.), 1980, 239: H14—H21.[4]Fung, Y. C., Biomechanics: Motion, Flow, Stress, and Growth, New York: Springer-Verlag, 1990.[5]Liu, S. Q., Biomechanical basis of vascular tissue engineering, Critical Reviews in Biomedical Engineering, 1999, 27: 75—148.[6]Ando, J., Kamiya, A., Blood flow and vascular endothelium cell function, Frontiers Med. Biological Eng., 1993, 5: 245—264.[7]Ku, D. N., Giddens, D. P., Zarins, D. K. et al., Pulsatile flow and atherosclerosis in the human carotid bifurcation-positive correlation between plaque location and low and oscillating shear stress, Atherosclerosis, 1985, 5: 293—302.[8]Liu Zhaorong, Li Xixi, Theory and Method on Hemodynamics (in Chinese), Shanghai: Fudan University Press, 1997.

  4. Physical entropy, information entropy and their evolution equations

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    [1]Langille, B. L., 7Donnell, F., Reductions in arterial diameter produced by chronic decreases in blood flow are endothelium-dependent, Science, 1986, 231: 405—407.[2]Langer, R., Vacanti, J. P., Tissue engineering, Science, 1993, 260: 920—926.[3]Kamiya, A., Togawa, T., Adaptive regulation of wall shear stress to flow change in the canine carotid artery, Am. J. Physiol. (Heart Circ. Physiol.), 1980, 239: H14—H21.[4]Fung, Y. C., Biomechanics: Motion, Flow, Stress, and Growth, New York: Springer-Verlag, 1990.[5]Liu, S. Q., Biomechanical basis of vascular tissue engineering, Critical Reviews in Biomedical Engineering, 1999, 27: 75—148.[6]Ando, J., Kamiya, A., Blood flow and vascular endothelium cell function, Frontiers Med. Biological Eng., 1993, 5: 245—264.[7]Ku, D. N., Giddens, D. P., Zarins, D. K. et al., Pulsatile flow and atherosclerosis in the human carotid bifurcation-positive correlation between plaque location and low and oscillating shear stress, Atherosclerosis, 1985, 5: 293—302.[8]Liu Zhaorong, Li Xixi, Theory and Method on Hemodynamics (in Chinese), Shanghai: Fudan University Press, 1997.

  5. Construction of many-particle spin entangled states and signature

    Institute of Scientific and Technical Information of China (English)

    ZHU; Hongbo

    2001-01-01

    [1]Langille, B. L., 7Donnell, F., Reductions in arterial diameter produced by chronic decreases in blood flow are endothelium-dependent, Science, 1986, 231: 405—407.[2]Langer, R., Vacanti, J. P., Tissue engineering, Science, 1993, 260: 920—926.[3]Kamiya, A., Togawa, T., Adaptive regulation of wall shear stress to flow change in the canine carotid artery, Am. J. Physiol. (Heart Circ. Physiol.), 1980, 239: H14—H21.[4]Fung, Y. C., Biomechanics: Motion, Flow, Stress, and Growth, New York: Springer-Verlag, 1990.[5]Liu, S. Q., Biomechanical basis of vascular tissue engineering, Critical Reviews in Biomedical Engineering, 1999, 27: 75—148.[6]Ando, J., Kamiya, A., Blood flow and vascular endothelium cell function, Frontiers Med. Biological Eng., 1993, 5: 245—264.[7]Ku, D. N., Giddens, D. P., Zarins, D. K. et al., Pulsatile flow and atherosclerosis in the human carotid bifurcation-positive correlation between plaque location and low and oscillating shear stress, Atherosclerosis, 1985, 5: 293—302.[8]Liu Zhaorong, Li Xixi, Theory and Method on Hemodynamics (in Chinese), Shanghai: Fudan University Press, 1997.

  6. Circadian rhythm of Z- and E-2-beta-D: -glucopyranosyloxy-4-methoxy cinnamic acids and herniarin in leaves of Matricaria chamomilla.

    Science.gov (United States)

    Repcák, Miroslav; Smajda, Benadik; Kovácik, Jozef; Eliasová, Adriana

    2009-07-01

    Chamomile (Matricaria chamomilla) in the above-ground organs synthesizes and accumulates (Z)- and (E)-2-beta-D: -glucopyranosyloxy-4-methoxy cinnamic acids (GMCA), the precursors of phytoanticipin herniarin (7-methoxycoumarin). The diurnal rhythmicity of the sum of GMCA (maximum before daybreak) and herniarin (acrophase at 10 h 21 min of circadian time) was observed under artificial lighting conditions LD 12:12. The acrophase is the time point of the maximum of the sinusoidal curve fitted to the experimental data. In continuous light, the circadian rhythms of both compounds were first described with similar acrophases of endogenous rhythms; a significantly different result from that in synchronized conditions. The rhythms' mesor (the mean value of the sinusoidal curve fitted to the experimental data) under free-running conditions was not influenced. Abiotic stress under synchronized conditions decreased the average content of GMCA to half of the original level and eliminated the rhythmicity. In contrast, the rhythm of herniarin continued, though its content significantly increased. Nitrogen deficiency resulted in a significant increase in GMCA content, which did not manifest any rhythmicity while the rhythm of herniarin continued. Circadian control of herniarin could be considered as a component of the plant's specialized defence mechanisms.

  7. Real Estate Taxes in Albania

    Directory of Open Access Journals (Sweden)

    Luciana Koprencka

    2013-04-01

    Full Text Available The construction sector is one of the mainsectors of the Albanian economy, which,during the last 20 years, has experiencedthe greatest economic growth. In 1991 thissector has contributed by 2.5% to the GDP,in 2006 by 4.9%, while in 2008, this sectorhas contributed by 14.9% to the national GDP. The relevant legislation has played animportant role in the development of this sector. The applied laws have tried to maintainat low levels the real estate prices and totransform such a problematic sector, withreference to fiscal evasion and informality,into an easily controllable sector. The taxesapplied in the construction sector are the sameas in other economic sectors, although thetaxation management in the construction sector, except forthose common principles thatregulate the tax management in general, isbased on some specificrules related to thecharacteristics of this sector. Increase the level of taxation on the transfer of ownership tothe extent of 10%, paralyzed the housing market by reducing the number of sales,especially of real estate old, previously this was 0.3-5%of sales value.JEL Classification: H21

  8. Virulence profiles of Shiga toxin-producing Escherichia coli and other potentially diarrheagenic E.coli of bovine origin, in Mendoza, Argentina

    Directory of Open Access Journals (Sweden)

    M.A. Pizarro

    2013-12-01

    Full Text Available This study described a group of strains obtained from a slaughter house in Mendoza, in terms of their pathogenic factors, serotype, antibiotype and molecular profile. Ninety one rectal swabs and one hundred eight plating samples taken from carcasses of healthy cattle intended for meat consumption were analyzed. Both the swab and the plate samples were processed to analyze the samples for the presence of virulence genes by PCR: stx1, stx2, eae and astA. The Stx positive strains were confirmed by citotoxicity assay in Vero cells. The isolates were subsequently investigated for their O:H serotype, antimicrobial susceptibility and molecular profile by Random Amplification of Polymorphic DNA (RAPD. Twelve E.coli strains were identified by their pathogenicity. Nine were from fecal origin and three from carcasses. Three strains carried the stx1 gene, three the stx2 gene, two carried eae and four the astA gene. The detected serotypes were: O172:H-; O150:H8; O91:H21; O178:H19 and O2:H5. The strains showed a similarity around 70% by RAPD. Some of the E.coli strains belonged to serogroups known for certain life-threatening diseases in humans. Their presence in carcasses indicates the high probability of bacterial spread during slaughter and processing.

  9. Synthesis and Crystal Structure of N-tert-butyl-N′-(2,4-dichlorobenzoyl)-N-[1-(4-chlorophenyl)-1, 4-dihydro-6-methylpyridazine-4-oxo-3- carbonyl] hydrazine

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The title compound N-tert-butyl-N¢-(2,4-dichlorobenzoyl)-N-[1-(4-chlorophenyl)- 1,4-dihydro-6-methylpyridazine-4-oxo-3-carbonyl]hydrazine [(C23H21N4O3Cl3)2·1.5H2O, Mr = 1042.60] was prepared by the reaction of 1-(4-chlorophenyl)-1,4-dihydro-4-oxo-6- methylpyridazine-3-carboxylic acid with chloroformate ethyl ester, then with N′-tert-butyl-N- (2,4-dichlorobenzoyl) hydrazine in the present of triethylamine. The crystal structure has been determined by X-ray diffraction. The crystal belongs to Monoclinic, space group P21/c, with unit cell constants a =11.4948(9), b=12.7495(10), c=35.854(3) ?, β =92.964(2)°, Z=4, V=5247.6(7) ?3, Dc = 1.320 Mg/m3, F(000) = 2156 , μ (MoKa)= 0.385, R = 0.0661, wR = 0.1875, for 9151 observed reflections( I >2σ(I)). The structure is a dimer linked by intermolecular hydrogen bond which can be observed between N(1)- H…O(6), N(5)- H…O(3). The distances are 2.068 and 2.027? respectively.

  10. Effect of vacuum oxy-nitrocarburizing on the microstructure of tool steels: an experimental and modeling study

    Directory of Open Access Journals (Sweden)

    Nikolova Maria

    2017-01-01

    Full Text Available The thermochemical treatments of tool steels improve the performance of the components with respect to surface hardness, wear and tribological performance as well as corrosion resistance. Compared to the conventional gas ferritic nitrocarburizing process, the original vacuum oxy-nitrocarburizing is a time-, cost-effective and environmentally-friendly gas process. Because of the oxidizing nature of the gas atmosphere, there is no need to perform subsequent post-oxidation.In this study, a vacuum oxynitrocarburizing process was carried out onto four tool steels (AISI H10, H11, H21 and D2 at 570 °C, after hardening and single tempering. The structural analysis of the compound and diffusion layers was performed by optical and electron microscopy, X-ray diffraction and glow discharge optical emission spectrometry (GDOES methods. A largely monophase ε- layer is formed with a carbon accumulation at the substrate adjacent area. The overlaying oxides adjacent to the ε-carbonitride phase contained Fe3O4 (magnetite as a main constituent. A thermodynamic modelling approach was also performed to understand and optimize the process. The “Equilib module” of FactSage software which uses Gibbs energy minimization method, was used to estimate the possible products during vacuum oxynitrocarburising process.

  11. Involvement of the nervous system following experimental infection with Pasteurella multocida B:2 in buffalo (Bubalus bubalis): A clinicopathological study.

    Science.gov (United States)

    Marza, Ali Dhiaa; Jesse, Faez Firdaus Abdullah; Ahmed, Ihsan Muneer; Chung, Eric Lim Teik; Ibrahim, Hayder Hamzah; Zamri-Saad, Mohd; Omar, Abdul Rahman; Abu Bakar, Md Zuki; Saharee, Abdul Aziz; Haron, Abdul Wahid; Alwan, Mohammed Jwaid; Lila, Mohd Azmi Mohd

    2016-04-01

    Haemorrhagic septicaemia (HS) is an acute, fatal, septicaemic disease of cattle and buffaloes caused by one of two specific serotypes of Pasteurella multocida B:2 and E:2 in Asian and African, respectively. It is well known that HS affect mainly the respiratory and digestive tracts. However, involvement of the nervous system in pathogenesis of HS has been reported in previous studies without details. In this study, nine buffalo calves of 8 months old were distributed into three groups. Animals of Group 1 and 2 were inoculated orally and subcutaneously with 10 ml of 1 × 10(12) cfu/ml of P. multocida B:2, respectively, while animals of Group 3 were inoculated orally with 10 ml of phosphate buffer saline as a control. All calves in Group 1 and Group 3 were euthanised after 504 h (21 day) post-infection, while calves in Group 2 had to euthanise after 12 h post-infection as they develop sever clinical signs of HS. Significant differences were found in Group 2 in the mean scores of clinical signs, gross and histopathological changes which mainly affect different anatomic regions of the nervous system. In addition, successful bacterial isolation of P. multocida B:2 were obtained from different sites of the nervous system. On the other hand, less sever, clinical, gross and histopathological changes were found in Group 1. These results provide for the first time strong evidence of involving of the nervous system in pathogenesis of HS, especially in the peracute stage of the disease.

  12. The effect of early detection of anterolateral thigh free flap crisis on the salvage success rate, based on 10 years of experience and 1072 flaps.

    Science.gov (United States)

    Yang, Q; Ren, Z H; Chickooree, D; Wu, H J; Tan, H Y; Wang, K; He, Z J; Gong, C J; Ram, V; Zhang, S

    2014-09-01

    The aim of this study was to assess the effectiveness of early exploration of anterolateral thigh (ALT) free flap compromise in head and neck reconstruction and to correlate this with the salvage success rate. The perioperative data of 1051 patients with 1072 ALT flap reconstructions were reviewed retrospectively for the period January 2002 to December 2012. Outcome measures included ethnicity, defect type, incidence and timing of flap compromise, type of flap compromise, causes of vascular occlusion, and salvage rate. The success rate of free flap reconstruction was 97.3% (1043/1072). Of the 29 failures, 21 were complete and eight were partial failures (10-40% of the flap). Venous occlusions occurred in 39 flaps (83.0%) and arterial occlusions in five flaps (17.0%). Six cases were detected within 8h postoperatively, 13 at 8-16 h postoperatively, seven at 16-24h postoperatively, and 18 at 24-48 h postoperatively, with respective salvage rates of 66.7%, 61.5%, 28.6%, and 22.2%; three cases detected after 48 h failed. The salvage rate at ≤16 h (62.2%) was much higher than that at >16 h (21.4%, P=0.0039). Early detection, re-exploration, and effective handling of the flap crisis increases the rate of flap salvage tremendously.

  13. Biological marker distribution in coexisting kerogen, bitumen and asphaltenes in Monterey Formation diatomite, California

    Science.gov (United States)

    Tannenbaum, E.; Ruth, E.; Huizinga, B. J.; Kaplan, I. R.

    1986-01-01

    Organic-rich (18.2%) Monterey Formation diatomite from California was studied. The organic matter consist of 94% bitumen and 6% kerogen. Biological markers from the bitumen and from pyrolysates of the coexisting asphaltenes and kerogen were analyzed in order to elucidate the relationship between the various fractions of the organic matter. While 17 alpha(H), 18 alpha(H), 21 alpha(H)-28,30-bisnorhopane was present in the bitumen and in the pryolysate of the asphaltenes, it was not detected in the pyrolysates of the kerogen. A C40-isoprenoid with "head to head" linkage, however, was present in pyrolysates of both kerogen and asphaltenes, but not in the bitumen from the diatomite. The maturation level of the bitumen, based on the extent of isomerization of steranes and hopanes, was that of a mature oil, whereas the pyrolysate from the kerogen showed a considerably lower maturation level. These relationships indicate that the bitumen may not be indigenous to the diatomite and that it is a mature oil that migrated into the rock. We consider the possibility, however, that some of the 28,30-bisnorhopane-rich Monterey Formation oils have not been generated through thermal degradation of kerogen, but have been expelled from the source rock at an early stage of diagenesis.

  14. μ3-Iodo-tri-μ3-sulfido-sulfidotris[tris(4-methoxyphenylphosphine-κP]tricopper(Itungsten(VI N,N-dimethylformide solvate

    Directory of Open Access Journals (Sweden)

    Guodong Tang

    2008-01-01

    Full Text Available A new W/S/Cu cluster, [Cu3WIS4(C21H21O3P3]·C3H7NO, was formed by the reaction of ammonium tetrathiotungstate(VI, cuprous iodide and tris(4-methoxyphenylphosphine in N,N-dimethylformamide. The title compound exhibits a heavily distorted cubane-like skeleton in which the average Cu—I, Cu—S and W—μ3-S distances are 2.934, 2.302 and 2.249 Å, respectively. The W atom exhibits tetrahedral geometry, formed by three μ3-S and one terminal S atom; the W—S(terminal bond length is 2.1426 (13 Å. Each Cu atom is coordinated by one P atom from a tris(4-methoxyphenylphosphine (mop, two μ3-S and one μ3-I atom, forming a distorted tetrahedral coordination geometry. Some of the mop ligand methyl groups have large librations. Together with the three neutral mop ligands, the title compound is neutral; this contrasts with the all-halogen-coordinated Mo/S/Ag clusters with the same structure, which carry negative charge.

  15. Bohr effect of human hemoglobin A: magnitude of negative contributions determined by the equilibrium between two tertiary structures.

    Science.gov (United States)

    Okonjo, Kehinde O; Olatunde, Abimbola M; Fodeke, Adedayo A; Babalola, J Oyebamiji

    2014-06-01

    We have measured the affinity of the CysF9[93]β sulfhydryl group of human deoxyhemoglobin and oxyhemoglobin for 5,5'-dithiobis(2-nitrobenzoate), DTNB, between pH ≈5.6 and 9 in order to understand the basis of the reported reduction of the Bohr effect induced by chemical modification of the sulfhydryl. We analyzed the results quantitatively on the basis of published data indicating that the sulfhydryl exists in two conformations that are coupled to the transition between two tertiary structures of hemoglobin in dynamic equilibrium. Our analyses show that the ionizable groups linked to the DTNB reaction have lower pKas of ionization in deoxyhemoglobin compared to oxyhemoglobin. So these ionizable groups should make negative contributions to the Bohr effect. We identify these groups as HisNA2[2]β, HisEF1[77]β and HisH21[143]β. We provide explanations for the finding that hemoglobin, chemically modified at CysF9[93]β, has a lower Bohr effect and a higher oxygen affinity than unmodified hemoglobin.

  16. Bis(3,5-dimethyl-1H-pyrazole-κN2bis(3,3′′,5,5′′-tetramethyl-[1,1′:3′,1′′-terphenyl]-2′-carboxylato-κOiron(II dichloromethane monosolvate

    Directory of Open Access Journals (Sweden)

    Yeojin Jeon

    2012-05-01

    Full Text Available In the title compound, [Fe(C23H21O22(C5H8N22]·CH2Cl2, the Fe2+ cation is coordinated by the N atoms of two 3,5-dimethylpyrazole ligands and the carboxylate O atoms from two tetramethylterphenylcarboxylate ligands, forming an FeN2O2 polyhedron with a slightly distorted tetrahedral coordination geometry. Intramolecular N—H...O and C—H...O hydrogen-bonding interactions stabilize the molecular conformation. The dihedral angles formed by the central benzene ring with the outer benzene rings of the terphenyl groups are 47.92 (8, 59.38 (8, 48.24 (8 and 52.37 (8°. The dichloromethane solvent molecule interacts with the complex molecule via a C—H...O hydrogen bond. In the crystal, centrosymmetrically related complex molecules are linked into dimers through pairs of C—H...O hydrogen bonds.

  17. Chemical activation of Lactoperoxidase system on preservation of raw milk at ambient temperature%室温下化学法激活乳过氧化物酶体系对原料乳品质的影响

    Institute of Scientific and Technical Information of China (English)

    胡晓宇; 陈梅仙; 卢蓉蓉; 张国农

    2007-01-01

    本文对化学法激活乳过氧化物酶体系用于室温下原料乳保鲜进行了研究.研究结果表明,在25℃贮藏温度下,原料奶的货架期随着SCN-和H2O2的浓度增加而增加.对照组和实验组0.1 mol/L,0.25 mmol/L,0.5 mmol/L的保鲜期分别为19 h,19.5 h,21.5 h和23.5 h.在贮藏期间,所有的实验组的微生物数量均低于对照组.11.5 h时,激活剂浓度为0.25 mmol/L和0.5 mmol/L的原料乳的菌落总数比对照组提高了3个卫生等级.在14h时,激活剂浓度为0.25 mmol/L和0.5 mmol/L的实验组比对照组的大肠菌群数分别低1.2和1.75个对数周期.

  18. Crystal structure of (4-meth-oxy-phen-yl)[(4-meth-oxy-phen-yl)phospho-nato]dioxidophosphate(1-) 2-amino-6-benzyl-3-eth-oxy-carbon-yl-4,5,6,7-tetra-hydro-thieno[2,3-c]pyridin-6-ium.

    Science.gov (United States)

    Mague, Joel T; Mohamed, Shaaban K; Akkurt, Mehmet; Younes, Sabry H H; Ahmed, Essam K; Albayati, Mustafa R

    2015-12-01

    The asymmetric unit of the title mol-ecular salt, C17H21N2O2S(+)·C14H15O7P2 (-), comprises two cations and two anions. Each cation features an intra-molecular N-H⋯O hydrogen bond, which closes an S(6) ring; in each case the hydro-pyridine ring adopts a half-chair conformation. In the anions, the dihedral angles between the aromatic rings are 64.1 (2) and 54.9 (2)°. In each case, the diphosphate groups are close to eclipsed [C-P⋯P-C pseudo-torsion angles = 11.6 (2) and -19.3 (2)°]. One of the meth-oxy groups in each anion is disordered over two orientations in a 0.539 (18):0.461 (18) ratio in one anion and 0.82 (2):0.18 (2) in the other. In the crystal, O-H⋯O and N-H⋯O hydrogen bonds link the components into [100] chains. Numerous C-H⋯O inter-actions cross-link the chains into a three-dimensional network.

  19. $\\eta$ Carinae Baby Homunculus Uncovered by ALMA

    CERN Document Server

    Abraham, Zulema; Beaklini, Pedro P B

    2014-01-01

    We report observations of $\\eta$ Carinae obtained with ALMA in the continuum of 100, 230, 280 and 660 GHz in 2012 November, with a resolution that varied from 2.88" to 0.45" for the lower and higher frequencies respectively. The source is not resolved, even at the highest frequency; its spectrum is characteristic of thermal bremsstrahlung of a compact source, but different from the spectrum of optically thin wind. The recombination lines H42$\\alpha$, He42$\\alpha$, H40$\\alpha$, He40$\\alpha$, H50$\\beta$, H28$\\alpha$, He28$\\alpha$, H21$\\alpha$ and He21$\\alpha$ were also detected and their intensities reveal non local thermodynamic equilibrium (NLTE) effects. We found that the line profiles could only be fit by an expanding shell of dense and ionized gas, which produces a slow shock in the surroundings of $\\eta$ Carinae. Combined with fittings to the continuum, we were able to constrain the shell size, radius, density, temperature and velocity. The detection of the He recombination lines is compatible with the hi...

  20. Th(Ⅳ)、U(Ⅵ)金刚烷胺Schiff碱配合物的合成、表征及抗菌活性%Synthesis, Characterization and Antibacterial Activity of Th(Ⅳ) and U(Ⅵ) Complexes with Schiff Base Derived from Adamantaneamine

    Institute of Scientific and Technical Information of China (English)

    祝智力; 赵国良; 张萍华; 沈丽金

    2005-01-01

    由金刚烷胺缩水杨醛Schiff碱配体(C17H21NO,以HL1表示)和金刚烷胺缩邻香兰素Schiff碱配体(C18H23NO2,以HL2表示)分别与UO2(Ac)2·2H2O和Th(NO3)4·4H2O作用,合成了四种新的配合物(1)[UO2(Ac)2(HL1)4]·1.5H2O,(2)[UO2(Ac)2(HL2)]·1.5H2O,(3)[Th(NO3)4(HL1)2]·H2O,(4)[Th(NO3)4(HL2)2]·H2O.用元素分析、摩尔电导、红外光谱和热重分析进行表征;并对所合成的配合物在DMF中进行了抗菌活性的初步测定,研究表明铀(Ⅵ)配合物有一定的抗菌活性,而钍(Ⅳ)配合物则无抗菌活性.

  1. The ALHAMBRA Project: A large area multi medium-band optical and NIR photometric survey

    CERN Document Server

    Moles, M; López-Aguerri, J A; Alfaro, E J; Broadhurst, T; Cabrera-Caño, J; Castander, F J; Cepa, J; Cerviño, M; Cristóbal-Hornillos, D; Fernández-Soto, A; Delgado, R M González; Infante, L; Márquez, I; Martínez, V J; Masegosa, J; del Olmo, A; Perea, J; Prada, F; Quintana, J M; Sánchez, S F

    2008-01-01

    (ABRIDGED) We describe the first results of the ALHAMBRA survey which provides cosmic tomography of the evolution of the contents of the Universe over most of Cosmic history. Our approach employs 20 contiguous, equal-width, medium-band filters covering from 3500 to 9700 A, plus the JHKs bands, to observe an area of 4 sqdeg on the sky. The optical photometric system has been designed to maximize the number of objects with accurate classification by SED and redshift, and to be sensitive to relatively faint emission lines. The observations are being carried out with the Calar Alto 3.5m telescope using the cameras LAICA and O-2000. The first data confirm that we are reaching the expected magnitude limits of AB<~25 mag in the optical filters from the blue to 8300 A, and from AB=24.7 to 23.4 for the redder ones. The limit in the NIR is (Vega) K_s~20, H~21, J~22. We expect to obtain accurate redshift values, Delta z/(1+z) <~ 0.03 for about 5x10^5 galaxies with I<~25 (60% complete), and z_med=0.74. This accu...

  2. Synthesis and crystal Structure of 2[1-(1,1-dimethylethyl)-5-methyl-1-H-pyrazol-4-ylcarbonyl]-N-Phenyldrazinecarbothioamide

    Institute of Scientific and Technical Information of China (English)

    李明; 文丽荣; 付维军; 赵桂龙; 杨华铮

    2004-01-01

    The crystal structure of 2[1-(1,1-dimethylethyl)-5-methyl-1-H-pyrazol-4-ylcar-bonyl]-N-phenyldrazinecarbothioamide ([C16H21N5OS]·CH3COCH3,C19H27N5O2S,Mr=389.52) has been determined by single-crystal X-ray diffraction.The crystal belongs to tetragonal,space group I41/a with a=23.960(4),b=23.960(4),c=16.120(5)A,V=9254(4)A3,Z=16,Dc=1.118 g/cm3,μ=0.161 mm-1,F(000)=3328,R=0.0660 and wR=0.1305 for 3878 unique reflections with 1653 observed ones (I > 2σ(I)).The intermolecular hydrogen bond between N(3)-H(3B)…O(1),N(5)-H(5A)…S(1) and N(4)-H(4D)…O(2) has been observed.

  3. Tamarugite in the Steam-Condensate Alteration Paragenesis in Diana Cave (SW Romania)

    Science.gov (United States)

    Puscas, C. M.; Onac, B. P.; Effenberger, H. S.; Povară, I.

    2012-12-01

    The double-salt hydrate tamarugite [NaAl(SO4)2 6H2O] is an uncommon mineral in the cave environment, forming as a result of chemical reactions between water and bedrock only under very specific conditions. The Diana Cave hosts a unique tamarugite occurrence, the first one to be reported from a typical karst environment. The cave is located within the limits of Băile Herculane township in the Cerna Mountains, SW Romania. It consists of a 14 m long, westward-oriented single passage, developed along the Diana Fault. In 1974 a concrete-clad mine gallery was created to channel the thermal water (Diana 1+2 Spring) flowing through the cave to a pumping station. The spring's chemical and physical parameters fluctuated through time, averaging 51.98° C, discharge of 0.96 Ls-1, pH of 7.46, 5768.66 ppm TDS, 9303 μScm-1 conductivity, 5.02 salinity. The major chemical components of the thermo-mineral water in Diana Cave are, Na+ (1392.57 ppm), K+ (58.55 ppm), Ca2+ (725.16 ppm), Mg2+ (10.78 ppm), Cl- (3376.83 ppm), and SO42- (92.27 ppm), and H2S (24.05 ppm), with traces of Si, Fe2+, Br+, I-, and Li+. The general air circulation pattern within the cave is fairly simple: cold air from the outside sweeps into the cave along the floor, heats up at the contact with the thermo-mineral water, ascends, and exists the cave along the ceiling. At the contact with the cold walls of the Diana Cave, the hot steam condenses and gives rise to a rich and exotic sulfate-mineral paragenesis (including halotrichite-series minerals, gypsum, bassanite, anhydrite, epsomite, alunite, halite, native sulfur, etc.). The most exotic minerals precipitate at or below the contact between the Tithonic - Neocomian limestone and the overlaying Cretaceous shaly limestone, as a result of steam-condensate alteration. Minerogenetic mechanisms responsible for the peculiar sulfate mineral assemblage in Diana Cave are evaporation, oxidation, hydrolysis, double exchange reactions, and deposition from vapours or

  4. Reconstruction of External Auditory Meatus (Re-EAMs) and Tympanoplasty for、Patients with Congenital Deformation of the Middle and Outer Ears%先天性中外耳畸形外耳道再造与鼓室成形术

    Institute of Scientific and Technical Information of China (English)

    邹艺辉; 杨仕明; 戴朴; 韩维举; 韩东一

    2014-01-01

    Objective To explore the hearing improvement after reconstruction of external auditory meatus (Re-EAMs) and tympanoplasty for patients with congenital deformation of the middle and outer ears, and provide reference for later treat⁃ment to these kinds of patients. Methods a retrospective analysis of 41 cases (41 ears) with preoperative and postoperative hearing findings undergone Re-EAMs and tympanoplasty patients with congenital deformation of the middle and outer ears in General Hospital of PLA during 2006.7-2012.12. Results The methods for operations were Ossicular chain loosening 41.5%(17/41),Porp implantation 46.3%(19/41), Torp implantation 7.3%(3/41) and inner ear fenestration 4.9%(2/41),with average air conduction hearing threshold pre-and post-operation for 0.5k、1k、2k、4k (58 dB/53dB),(64 dB/52dB),(73 dB/73dB)and (62 dB/46dB)respectively. Conclusion Hearing improvement is not obvious after ossicular chain loosening and Torp implan⁃tation, while significant for Porp implantation and inner ear fenestration, but can’t reach the normal hearing threshold level.%目的:探索先天性中外耳畸形患者耳道再造与鼓室成形术后听力改善情况,为此类患者方案选择提供参考。方法回顾性分析2006年6月~2012年12月我们进行外耳道再造与鼓室成形患者中有术前术后听力的41例(41耳)的情况。结果手术采用听骨链松解41.5%(17/41),Porp植入46.3%(19/41),Torp植入7.3%(3/41),内耳开窗4.9%(2/41)。术前术后0.5k、1k、2k、4k平均气导听阈值分别为(58 dB/53dB),(64 dB/52dB),(73 dB/73dB),(62 dB/46dB).结论听骨链松解与Torp植入术后听力改善不明显,Porp植入和内耳开窗术后听力有明显改善,但未能达到正常听阈水平。

  5. 电导法对32个辣椒品种组合抗寒性的测定及配合力分析%Determination and Combining Ability Analysis of Cold Resistance of 32 Combinations of Hot Peper Hybrid by Electric Conductivity

    Institute of Scientific and Technical Information of China (English)

    杨少瑕; 吕庆芳; 梁春林

    2014-01-01

    为了比较辣椒品种的抗寒性,以32个线椒杂交组合为试材,在人工气候箱下进行低温处理,应用电导法测定叶片相对电导率(REC)。通过Logistic曲线方程拟合求出拐点温度(即半致死温度)(LT50),作为各试材抗寒性评价的参考指标,并将32个线椒组合的半致死温度(L T50)进行比较。结果表明:随处理温度的降低,相对电导率不断升高,变化过程呈“S”型曲线。32个线椒组合抗寒性顺序依次为:H2> H13≈ H28> H31≈H1≈H23> H24> H26> H30> H8> H27≈ H19> H5≈ H12> H21> H3> H18> H15≈ H14> H22> H17>H7≈H29> H4> H11> H10≈H16> H20> H6> H9> H25> H32。配合力分析表明,相对电导率的GCA效应值以亲本P1和P2最低,SCA效应值以P1× P2最低。%In order to compare the cold resistance of the hot pepper varieties ,taking 32 combinations of hot pep-per hybrid as materials ,the relative electrical conductivity was deteriminated under low temperature in artificial climatic .The turning point temperature(semi-lethal temperature)was measured by Logistic equation and used as the index of cold-tolerance for all hybrid combinations ,the semi-lethal temperatures were compared .The re-sults showed that relative conductivity was increasing with the decrease of temperature ,change processing was in an S curve .The order of cold resistance of hot peppers was H2> H13≈ H28> H31≈ H1≈ H23> H24>H26> H30> H8> H27≈ H19> H5≈H12> H21> H3> H18> H15≈ H14> H22> H17> H7≈ H29> H4>H11> H10≈ H16> H20> H6> H9> H25> H32 .Combining ability analysis showed that the lowest GCA effect of relative conductivity was parent P1 and P2 ,the lowest SCA was P1 × P2 .

  6. 含苯四甲酸的邻菲啰啉铜配合物的合成、晶体结构及电化学性质研究%Synthesis, Crystal Structure and Electrochemical Property of Copper Complex Based on 1,10-Phenanthroline and 1,2,4,5-Benzenetetracarboxylic Acid

    Institute of Scientific and Technical Information of China (English)

    朱禹; 黄文浩; 朱敏; 吴云龙; 谢吉民

    2013-01-01

    A Cu(Ⅱ) complex [Cu (phen)2Br] (H3BTEC) (1,phen =1,10-phenanthroline,H4BTEC =1,2,4,5-benzenetetracarboxylic acid) was synthesized,and charactered by elemental analysis,IR spectra,UV-Vis spectra,single crystal X-ray diffraction,TG analysis and electrochemical property.The complex crystallizes in triclinic,space group P1 with a=0.971 00(19) nm,b=1.212 0(2) nm,c=1.4290(3) nm; α=102.21(3)°,β=99.57(3)°,γ=107.64(3)°,V=1.51774(7) nm3,Z=2,C34H21BrCuN4O8,Mr=757,Dc=1.656 g·cm-3,μ=2.098 mm-1,F(000)=762,S=1.059,the final R=0.044 9 and wR=0.086 4 for 4 657 observed reflections with I>2o(I).Two types of one-dimensional chains are demonstrated in the structure.On one hand,the C-H… Br hydrogen bonds and Br…π stacking interactions connect the [Cu(phen)2Br]+ cations into one-dimensional chains; on the other hand,the O-H… O hydrogen bonds aggregate the mono-deprotonated anions into one-dimensional double-layer chains.The two different kinds of chains are further packed into a three-dimensional framework with C-H…O contacts.CCDC:858948.%本文合成了铜配合物[Cu(phen)2Br](H3BTEC)(1,phen=1,10-phenanthroline,H4BTEC=1,2,4,5-benzenetetracarboxylic acid),并对其进行了元素分析、红外、紫外、单晶衍射、热重和电化学性质等表征.测定结果表明,该配合物晶体属三斜晶系,空间群P(1-),晶胞参数a=0.971 00(19) nm,b=1.212 0(2) nm,c=1.429 0(3) nm;α=102.21 (3)°,β=99.57(3)°,γ=107.64(3)°,V=1.517 74(7) nm3,Z=2,C34H21BrCuN4O8,M=757,Dc=1.656 g·cm-3,μ=2.098 mm-1,F(000)=762,S=1.059,最终偏离因子R=0.044 9,wR=0.086 4.该配合物中发现了两种不同类型的一维链.一方面,氢键(C-H…Br)和Br…π堆积作用将[Cu(phen)2Br]+连接成一个一维阳离子链;另外,分子间的O-H…O氢键将均苯四甲酸连成一个双层的一维阴离子链.通过结构中的C-H…O氢键作用及其他弱作用将这两条不同的一维链堆积成一个三维结构.

  7. Assessment of extreme quantitative precipitation forecasts and development of regional extreme event thresholds using data from HMT-2006 and COOP observers

    Science.gov (United States)

    Ralph, F.M.; Sukovich, E.; Reynolds, D.; Dettinger, M.; Weagle, S.; Clark, W.; Neiman, P.J.

    2010-01-01

    Extreme precipitation events, and the quantitative precipitation forecasts (QPFs) associated with them, are examined. The study uses data from the Hydrometeorology Testbed (HMT), which conducted its first field study in California during the 2005/06 cool season. National Weather Service River Forecast Center (NWS RFC) gridded QPFs for 24-h periods at 24-h (day 1), 48-h (day 2), and 72-h (day 3) forecast lead times plus 24-h quantitative precipitation estimates (QPEs) fromsites in California (CA) and Oregon-Washington (OR-WA) are used. During the 172-day period studied, some sites received more than 254 cm (100 in.) of precipitation. The winter season produced many extreme precipitation events, including 90 instances when a site received more than 7.6 cm (3.0 in.) of precipitation in 24 h (i.e., an "event") and 17 events that exceeded 12.7 cm (24 h)-1 [5.0 in. (24 h)-1]. For the 90 extreme events f.7.6 cm (24 h)-1 [3.0 in. (24 h)-1]g, almost 90% of all the 270 QPFs (days 1-3) were biased low, increasingly so with greater lead time. Of the 17 observed events exceeding 12.7 cm (24 h)-1 [5.0 in. (24 h)-1], only 1 of those events was predicted to be that extreme. Almost all of the extreme events correlated with the presence of atmospheric river conditions. Total seasonal QPF biases for all events fi.e., $0.025 cm (24 h)-1 [0.01 in. (24 h)-1]g were sensitive to local geography and were generally biased low in the California-Nevada River Forecast Center (CNRFC) region and high in the Northwest River Forecast Center(NWRFC) domain. The low bias in CA QPFs improved with shorter forecast lead time and worsened for extreme events. Differences were also noted between the CNRFC and NWRFC in terms of QPF and the frequency of extreme events. A key finding from this study is that there were more precipitation events .7.6 cm (24 h)-1 [3.0 in. (24 h)21] in CA than in OR-WA. Examination of 422 Cooperative Observer Program (COOP) sites in the NWRFC domain and 400 in the CNRFC domain

  8. Influência do período de alimentação no consumo e ganho de peso do pirarucu Influence of feeding period on consumption and weight gain of pirarucu

    Directory of Open Access Journals (Sweden)

    Roger Crescêncio

    2005-12-01

    Full Text Available O objetivo deste trabalho foi verificar o período preferencial de consumo alimentar do pirarucu, Arapaima gigas, e a influência de diferentes turnos de alimentação no consumo e ganho de peso dessa espécie. Foram testados três tratamentos: alimentação diurna (peixes alimentados às 9h e 15h, alimentação noturna (peixes alimentados às 21h e 3h e alimentação contínua (peixes alimentados às 9h, 15h, 21h e 3h. Cada tratamento foi avaliado em triplicata, com cada unidade experimental formada por oito peixes, com peso médio de 313 g, estocados em tanques-redes de 1 m³ (1x1x1 m. Os nove tanques-redes foram alocados em um viveiro escavado de 120 m². O experimento durou 60 dias. A alimentação contínua promoveu maiores ganhos de peso e biomassa, taxa de crescimento específico e consumo total. Os tratamentos alimentação diurna e alimentação noturna apresentaram ganho de peso semelhante, porém, a alimentação diurna apresentou a melhor conversão alimentar. O período preferencial de alimentação do pirarucu foi o noturno, principalmente no começo da noite. Os dados deste estudo indicam que o horário de preferência alimentar não é o melhor horário de alimentação do pirarucu, em uma criação comercial. O período de alimentação mais indicado para a espécie, baseado na capacidade de conversão alimentar, é o diurno.The objective of this study was to verify pirarucu Arapaima gigas preferential time of feeding, and the influence of different feeding periods on consumption and weight gain of this species. Three treatments were tested: diurnal feeding (fish fed at 9h and 15h, nocturnal feeding (fish fed at 21h and 3h, and continuous feeding (fish fed at 9h, 15h, 21h and 3h. Each treatment was evaluated in triplicate, and each trial unit had eight fishes with 313 g average weight, stoked into a 1 m³ (1x1x1 m net cage. The nine net cages were located on a 120 m² earth pond. The trial lasted for 60 days. Continuous feeding

  9. INTERSCALENE BRACHIAL PLEXUS BLOCK: COMPARISON OF EFFICACY OF VARYING DOSES OF DEXAMETHASONE COMBINED WITH LEVOBUPIVACAINE: A DOUBLE-BLIND RANDOMISED TRAIL.

    Directory of Open Access Journals (Sweden)

    Srinivasa Rao

    2014-06-01

    Full Text Available INTRODUCTION: To compare the effects of adding two different doses of dexamethasone on the duration and quality of interscalene block in patients undergoing shoulder surgery. METHODOLOGY: A total of 90 patients(age 18-65years undergoing shoulder surgery under interscalene block were assigned randomly to one of three groups: Control Group-C received injection levobupivacaine (0.5%, 35ml plus 2 ml normal saline Group-L received injection levobupivacaine (0.5% 35 ml plus dexamethasone 4 mg plus 1 ml normal saline and; Group H received injection levobupivacaine (0.5% 35 ml plus dexamethasone 8 mg. Assessment of motor and sensory blockade, pulse, systolic blood pressure, respiration and side effects were noted every 5 minutes for first 30 minute and every 10 minute till the end of surgery. Postoperative analgesia was assessed using the numeric rating scores [NRS]. RESULTS: The duration of analgesia was significantly prolonged in both Group L (19.2 ± 2.6 h and Group H (21.3 ± 1.7 h compared with Group C (11.6 ± 1.1 h (p<0.05. Similarly, the duration of motor block was longer in both Group L (26.6 ± 2.8 h, and Group H (28.4 ± 2.2 h compared to Group C (18.6 ± 3.1 h (p<0.05. Postoperative analgesic consumption for the first 48 hours was significantly lower in Group L (6.5 [4–8] tabs and in Group H (5.5 [4–7] tabs vs. 9.5 [8–12] tabs in Group C (p<0.01. CONCLUSION: The addition of dexamethasone to levobupivacaine significantly prolonged the duration of the motor block and improved the quality of analgesia following interscalene block. There was no difference in the duration of analgesia and motor block between low-dose and high-dose dexamethasone.

  10. HYDRA VULGARIS PALLAS, 1766 (HYDROZOA: HYDRIDAE AS BIOINDICATOR OF THE WATER QUALITY OF THE RIVER CHILI, AREQUIPA, PERU

    Directory of Open Access Journals (Sweden)

    Ronald Huarachi

    2012-12-01

    Full Text Available The aim of this study was to use Hydra vulgaris Pallas, 1766 (Hydrozoa: Hydridae as a bioindicator of water quality of the Chili River, Arequipa, Peru. The freshwater hydra were collected in the spring "Ojo del Milagro", Characato District, Arequipa, Peru. H. vulgaris was cultivated under standardized conditions and were fed Artemia sp. K2Cr2O7 was used as a positive control and as a reference toxin. Acute toxicity and morphological changes of H. vulgaris were evaluated on Tiabaya and Tingo, sampling points of the Chili River. The LC50 (median lethal concentration showed: Tingo (LC50-96h = 135.95% classifying it as non-toxic and Tiabaya (LC50 -24h = 61.83%, classifying it as moderately toxic; LC50-48h = 44.19% and LC50 -72h = 38.28% classifying them as toxic; LC50 -96h = 21.44% rating it as very toxic. Significant differences in the morphological changes of H. vulgaris were observed with regard to different concentrations and exposure time in waters sampled from Tingo from 48 h to 96 h and in Tiabaya, significant differences in morphological changes from 24 h to 96 h exposure. The results of the physicochemical parameters of the Chili River were compared with the Peruvian National Standards for Environmental Quality (ECA for water (categories 3 and 4 and recorded high values of biochemical oxygen demand BOD5, NH4 and PO4, and low dissolved oxigen OD values for Tiabaya. In Tingo, NH4 and phosphate were high. In Tiabaya, water was considered more toxic than at Tingo.

  11. Topological data analysis of Escherichia coli O157:H7 and non-O157 survival in soils.

    Science.gov (United States)

    Ibekwe, Abasiofiok M; Ma, Jincai; Crowley, David E; Yang, Ching-Hong; Johnson, Alexis M; Petrossian, Tanya C; Lum, Pek Y

    2014-01-01

    Shiga toxin-producing E. coli O157:H7 and non-O157 have been implicated in many foodborne illnesses caused by the consumption of contaminated fresh produce. However, data on their persistence in soils are limited due to the complexity in datasets generated from different environmental variables and bacterial taxa. There is a continuing need to distinguish the various environmental variables and different bacterial groups to understand the relationships among these factors and the pathogen survival. Using an approach called Topological Data Analysis (TDA); we reconstructed the relationship structure of E. coli O157 and non-O157 survival in 32 soils (16 organic and 16 conventionally managed soils) from California (CA) and Arizona (AZ) with a multi-resolution output. In our study, we took a community approach based on total soil microbiome to study community level survival and examining the network of the community as a whole and the relationship between its topology and biological processes. TDA produces a geometric representation of complex data sets. Network analysis showed that Shiga toxin negative strain E. coli O157:H7 4554 survived significantly longer in comparison to E. coli O157:H7 EDL 933, while the survival time of E. coli O157:NM was comparable to that of E. coli O157:H7 EDL 933 in all of the tested soils. Two non-O157 strains, E. coli O26:H11 and E. coli O103:H2 survived much longer than E. coli O91:H21 and the three strains of E. coli O157. We show that there are complex interactions between E. coli strain survival, microbial community structures, and soil parameters.

  12. Characteristics of particulate carbon emissions from real-world Chinese coal combustion.

    Science.gov (United States)

    Zhang, Yuanxun; Schauer, James Jay; Zhang, Yuanhang; Zeng, Limin; Wei, Yongjie; Liu, Yuan; Shao, Min

    2008-07-15

    Particulate matter emissions from a series of different Chinese coal combustion systems were collected and analyzed for elemental and organic carbon (EC, OC), and molecular markers. Emissions from both industrial boilers and residential stoves were investigated. The coal used in this study included anthracite, bituminite, and brown coal, as well as commonly used coal briquettes produced in China for residential coal combustion. Results show significant differences in the contribution of carbonaceous species to particulate mass emissions. Industrial boilers had much higher burn out of carbon yielding particulate matter emissions with much lower levels of OC, EC, and speciated organic compounds, while residential stoves had significantly higher emissions of carbonaceous particulate matter with emission rates of approximately 100 times higher than that of industrial boilers. Quantified organic compounds emitted from industrial boilers were dominated by oxygenated compounds, of which 46-68% were organic acids, whereas the dominate species quantified in the emissions from residential stoves were PAHs (38%) and n-alkanes (20%). An important observation was the fact that emission factors of PAHs and the distribution of hopanoids were different among the emissions from industrial and residential coal combustion even using the same coal for combustion. Although particulate matter emissions from industrial and residential combustion were different in many regards, picene was detected in all samples with detectable OC mass concentrations, which supports the use of this organic tracer for OC from all types of coal combustion. 17alpha(H),21beta(H)-29-norhopane was the predominant hopanoid in coal combustion emissions, which is different from mobile source emissions and may be used to distinguish emissions from these different fossil fuel sources.

  13. Deposition and Biodegradation of Submerged Oil from the Deepwater Horizon

    Science.gov (United States)

    Bagby, S. C.; Fisher, G. B.; Reddy, C. M.; Valentine, D. L.

    2014-12-01

    The 2010 sinking of the Deepwater Horizon in the Gulf of Mexico caused the release of ~5 million barrels of oil to the deep ocean. Roughly half of this oil, ~2 million barrels, is believed to have been trapped ~1000-1300 m deep in the water column, in plumes comprising water-soluble hydrocarbons in the aqueous phase and water-insoluble oil particles in suspension. While the soluble fraction was subject to rapid biodegradation, the fate of the oil particles has remained unknown. Using 17α(H),21β(H)-hopane (hopane) as a conservative marker of water-insoluble crude oil, we have examined the sediment data collected in support of the Natural Resource Damage Assessment process and identified a 3200-km2 depositional footprint surrounding the Macondo well. Under conservative assumptions, we estimate that this footprint accounts for ~12% of the suspended liquid oil. Monte Carlo modeling of the distribution of surficial hopane concentrations provides an initial estimate of the size distribution and spatial density of deposited particles, and suggests that the local spatial heterogeneity of particle deposition is likely to be extremely high, such that low-density sediment sampling is unlikely to capture the true extent of deposition. Thus, the 'missing' oil may be hiding in plain sight. Finally, we examined the spatial and temporal concentration distribution of >100 hydrocarbon compounds in relation to hopane, finding that, while there is clear evidence for biodegradation of many compounds, biodegradative efficiency appears to be impeded by high concentrations of oil, perhaps reflecting the low surface area to volume ratio of large oil particles.

  14. High indium content graded channel GainAs/AlinAs pseudomorphic MODFETs

    Science.gov (United States)

    Laskar, J.; Kolodzey, J.; Boor, S.; Hsieh, K. C.; Kalem, S.; Caracci, S.; Ketterson, A. A.; Brock, T.; Adesida, I.; Sivco, D.; Cho, A. Y.

    1990-03-01

    We report on the electrical and microstructural properties of InP/GaxIn 1 -xAs/Al0.48In0.52As modulation doped layers having compositionally graded active channels with different channel thicknesses. The layers were grown by solid source molecular beam epitaxy on Fe-doped InP substrates. The undoped GaInAs two dimensional electron gas channel layers were grown having indium compositions graded from x = 0.53 at the substrate buffer to x= 0.65 at the heterointerface by varying the Ga cell temperature during growth. Active channel thicknesses of 20 nm and 30 nm were compared with lattice matched layers. Transmission electron microscope image analysis indicates no misfit dislocations in these structures. Hall-effect measurements at 300 K show an increase in the mobility from 8,380 cm2/Vs for the lattice matched layer to 12,500 cm2/Vs for the 30 nm pseudomorphic layer. Small gate-length, 0.25 μn, MODFETs were fabricated to determine effective velocity values from transconductance ( g m ) and current gain ( h 21 ) measurements. The peak dc extrinsic g m increased from 367 mS/mm for the lattice matched layer to 668 mS/mm for the 30 nm pseudomorphic layer. The effective electron carrier velocity increased from 1.57 × 107 cm/s for the lattice matched layer to 1.88 × 107 cm/s for the 30 nm pseudomorphic layer. Our results show that compositional grading is a useful technique to obtain thick pseudomorphic layers with good transport properties.

  15. In-stream attenuation of neuro-active pharmaceuticals and their metabolites

    Science.gov (United States)

    Writer, Jeffrey; Antweiler, Ronald C.; Ferrar, Imma; Ryan, Joseph N.; Thurman, Michael

    2013-01-01

    In-stream attenuation was determined for 14 neuro-active pharmaceuticals and associated metabolites. Lagrangian sampling, which follows a parcel of water as it moves downstream, was used to link hydrological and chemical transformation processes. Wastewater loading of neuro-active compounds varied considerably over a span of several hours, and thus a sampling regime was used to verify that the Lagrangian parcel was being sampled and a mechanism was developed to correct measured concentrations if it was not. In-stream attenuation over the 5.4-km evaluated reach could be modeled as pseudo-first-order decay for 11 of the 14 evaluated neuro-active pharmaceutical compounds, illustrating the capacity of streams to reduce conveyance of neuro-active compounds downstream. Fluoxetine and N-desmethyl citalopram were the most rapidly attenuated compounds (t1/2 = 3.6 ± 0.3 h, 4.0 ± 0.2 h, respectively). Lamotrigine, 10,11,-dihydro-10,11,-dihydroxy-carbamazepine, and carbamazepine were the most persistent (t1/2 = 12 ± 2.0 h, 12 ± 2.6 h, 21 ± 4.5 h, respectively). Parent compounds (e.g., buproprion, carbamazepine, lamotrigine) generally were more persistent relative to their metabolites. Several compounds (citalopram, venlafaxine, O-desmethyl-venlafaxine) were not attenuated. It was postulated that the primary mechanism of removal for these compounds was interaction with bed sediments and stream biofilms, based on measured concentrations in stream biofilms and a column experiment using stream sediments.

  16. Crystal structure of 2A proteinase from hand, foot and mouth disease virus.

    Science.gov (United States)

    Mu, Zhixia; Wang, Bei; Zhang, Xiaoyu; Gao, Xiaopan; Qin, Bo; Zhao, Zhendong; Cui, Sheng

    2013-11-15

    EV71 is responsible for several epidemics worldwide; however, the effective antiviral drug is unavailable to date. The 2A proteinase (2A(pro)) of EV71 presents a promising drug target due to its multiple roles in virus replication, inhibition of host protein synthesis and evasion of innate immunity. We determined the crystal structure of EV71 2A(pro) at 1.85Å resolution, revealing that the proteinase maintains a chymotrypsin-like fold. The active site is composed of the catalytic triads C110A, H21 and D39 with the geometry similar to that in other picornaviral 2A(pro), 3C(pro) and serine proteinases. The cI-to-eI2 loop at the N-terminal domain of EV71 2A(pro) adopts a highly stable conformation and contributes to the hydrophilic surface property, which are strikingly different in HRV2 2A(pro) but are similar in CVB4 2A(pro). We identified a hydrophobic motif "LLWL" followed by an acidic motif "DEE" at the C-terminus of EV71 2A(pro). The "LLWL" motif is folded into the β-turn structure that is essential for the positioning of the acidic motif. Our structural and mutagenesis study demonstrated that both the negative charging and the correct positioning of the C-terminus are essential for EV71 replication. Deletion of the "LLWL" motif abrogated the proteolytic activity, indicating that the motif is critical for maintaining the active proteinase conformation. Our findings provide the structural and functional insights into EV71 2A(pro) and establish a framework for structure-based inhibitor design.

  17. Differential Expression of Three Hypoxia-inducible Factor-α Subunits in Pulmonary Arteries of Rat with Hypoxia-induced Hypertension

    Institute of Scientific and Technical Information of China (English)

    Qi-Fang LI; Ai-Guo DAI

    2005-01-01

    Hypoxia inducible transcription factor (HIF)-1α plays an important role in the development of hypoxic pulmonary hypertension, but little is known about HIF-2α and HIF-3α with respect to transcriptional regulation by hypoxia. To examine the expression patterns of all HIF-α subunits (HIF-1α, HIF-2α and HIF-3α) in pulmonary arteries of rats undergoing systemic hypoxia, five groups of healthy male Wistar rats were exposed to normoxia (N) and hypoxia for 3 (H3), 7 (H7), 14 (H14) and 21 (H21) d respectively. Mean pulmonary arterial pressure (mPAP), vessel morphometry and right ventricular hypertrophy index were measured. Lungs were inflation fixed for immunohistochemistry and in situ hybridization, and homogenized for Western blot. mPAP increased significantly after 7 d of hypoxia [(18.4±0.4) vs. (14.4±0.4) mmHg, H7 vs.N], reached its peak after 14 d of hypoxia, then remained stable. Pulmonary artery remodeling and right ventricular hypertrophy developed significantly after 14 d of hypoxia. During normoxia, HIF-1 α and HIF-3α staining were slightly positive regarding mRNA levels. A substantial alteration of HIF-1 α and HIF-3α staining occurred in pulmonary arteries after 14 d and 7 d of hypoxia, respectively, but HIF-2α stainin g showed an inversed trend after 14 d of hypoxia. Protein levels of all HIF-α subunits except HIF-3α showed a marked increase corresponding to the duration of hypoxia, which was obtained by Western blot. Our study found that HIF-1 α, HIF-2α and HIF-3α may not only confer different target genes, but also play key pathogenetic roles in hypoxic-induced pulmonary hypertension.

  18. Syntheses, Crystal Structures and Fluorescent Properties of Two New Imidazolidino Schiff Base Compounds

    Institute of Scientific and Technical Information of China (English)

    FENG Yue; LIU Gang; TIAN Xiu-Mei; WANG Ji-De; WANG Wei

    2008-01-01

    Two new imidazolidino Schiff base compounds, (E)-N-((quinoxalin-2-yl)methylene)-2-(2-(quinoxalin-3-yl)imidazolidin-1-yl)ethanamine 1 and 2-(1-(2-(2-(quinoxalin-3-yl)imidazolidin-1-yl)ethyl)imidazolidin-2-yl)quinoxaline 2, have been synthesized and characterized by elemental analysis,1H NMR, IR, MS and single-crystal X-ray diffraction. Crystallographic data for 1: C22H21N7,Mr = 383.46, monoclinic, space group P21, a = 7.0036(14), b=6.9151(14), c=19.701(4)(A),β=96.57(3)°, Z = 2, V=947.9(3)(A)3, Dc = 1.344 g/cm3, F(000)=404, μ = 0.085 mm-1, Flack parameter =0(2), R = 0.0464 and wR = 0.1055; and those for 2: C24H26N8, Mr = 426.53, triclinic, space group P(1),a = 9.6680(19), b = 10.334(2), c = 11.389(2)(A),α= 104.12(3),β= 102.95(3),γ= 100.48(3)°, Z=2,V=1041.2(4)(A)3, Dc=1.361 g/cm3, F(000) = 452,μ = 0.086 mm-1, R = 0.0373 and wR = 0.1155. For the two compounds, the five-membered imidazolidine rings all adopt envelope conformation.Moreover, the title compounds show one-dimensional layered and three-dimensional supramolecular chainlike structures, respectively. Fluorescent properties of the two compounds have been investigated in the solid state at room temperature. Compound 1 exhibits strong fluorescence and thus may serve as excellent candidates of green fluorescent materials.

  19. An extreme mountain ultra-marathon decreases the cost of uphill walking and running

    Directory of Open Access Journals (Sweden)

    Gianluca Vernillo

    2016-11-01

    Full Text Available Purpose: To examine the effects of the world’s most challenging mountain ultramarathon (MUM, 330 km, cumulative elevation gain of +24000 m on the energy cost and kinematics of different uphill gaits. Methods: Before (PRE and immediately after (POST the competition, 19 male athletes performed three submaximal 5-min treadmill exercise trials in a randomized order: walking at 5 km·h-1, +20%; running at 6 km·h-1, +15%; and running at 8 km·h-1, +10%. During the three trials, energy cost was assessed using an indirect calorimetry system and spatiotemporal gait parameters were acquired with a floor-level high-density photoelectric cells system. Results: The average time of the study participants to complete the MUM was 129 h 43 min 48 s (range: 107 h 29 min 24 s to 144 h 21 min 0 s. Energy costs in walking (-11.5 ± 5.5%, P < 0.001, as well as in the first (-7.2 ± 3.1%, P = 0.01 and second (-7.0 ± 3.9%, P = 0.02 running condition decreased between PRE and POST, with a reduction both in the heart rate (-11.3%, -10.0%, and -9.3%, respectively and oxygen uptake only for the walking condition (-6.5%. No consistent and significant changes in the kinematics variables were detected (P values from 0.10 to 0.96. Conclusion: Though fatigued after completing the MUM, the subjects were still able to maintain their uphill locomotion patterns noted at PRE. The decrease (improvement in the energy costs was likely due to the prolonged and repetitive walking/running, reflecting a generic improvement in the mechanical efficiency of locomotion after ~130 h of uphill locomotion rather than constraints imposed by the activity on the musculoskeletal structure and function.

  20. An Extreme Mountain Ultra-Marathon Decreases the Cost of Uphill Walking and Running.

    Science.gov (United States)

    Vernillo, Gianluca; Savoldelli, Aldo; Skafidas, Spyros; Zignoli, Andrea; La Torre, Antonio; Pellegrini, Barbara; Giardini, Guido; Trabucchi, Pietro; Millet, Grégoire P; Schena, Federico

    2016-01-01

    Purpose: To examine the effects of the world's most challenging mountain ultramarathon (MUM, 330 km, cumulative elevation gain of +24,000 m) on the energy cost and kinematics of different uphill gaits. Methods: Before (PRE) and immediately after (POST) the competition, 19 male athletes performed three submaximal 5-min treadmill exercise trials in a randomized order: walking at 5 km·h(-1), +20%; running at 6 km·h(-1), +15%; and running at 8 km·h(-1), +10%. During the three trials, energy cost was assessed using an indirect calorimetry system and spatiotemporal gait parameters were acquired with a floor-level high-density photoelectric cells system. Results: The average time of the study participants to complete the MUM was 129 h 43 min 48 s (range: 107 h 29 min 24 s to 144 h 21 min 0 s). Energy costs in walking (-11.5 ± 5.5%, P running condition decreased between PRE and POST, with a reduction both in the heart rate (-11.3, -10.0, and -9.3%, respectively) and oxygen uptake only for the walking condition (-6.5%). No consistent and significant changes in the kinematics variables were detected (P-values from 0.10 to 0.96). Conclusion: Though fatigued after completing the MUM, the subjects were still able to maintain their uphill locomotion patterns noted at PRE. The decrease (improvement) in the energy costs was likely due to the prolonged and repetitive walking/running, reflecting a generic improvement in the mechanical efficiency of locomotion after ~130 h of uphill locomotion rather than constraints imposed by the activity on the musculoskeletal structure and function.

  1. Colorimetric chemosensor of symmetrical benzoylthiourea derivatives as for detection of Cu2+ in aqueous solution

    Science.gov (United States)

    Hamedan, N. A.; Hasan, S.; Zaki, H. M.; Alias, N. Z.

    2017-02-01

    A novel receptor, designed with a combination of oxygen (O), nitrogen (N) and sulfur (S) -binding sites for metal ions was synthesized. Ortho (A), meta (B) and para (C) bearing benzoyl thiourea were designed and synthesized with triamine group to apply as colorimetric chemosensors for detection of Cu2+. The structure was confirmed by characterized the compound using Elemental analysis, Fourier Infrared (FTIR) and proton Nuclear Magnetic Resonance (1H NMR) spectroscopy. Functional groups of C=O, N-H, C=N and C=S were found at 1677 cm-1, 3240 cm-1, 1591 cm-1, 1024 cm-1 respectively while 1H NMR shows peaks of alkane (CH2), benzene (Ar-H), CONH, CSNH at 3.68 – 4.14, 7.16 – 7.86, 8.74, and 9.2 respectively. Elemental analysis for A, B and C C20H21N5O2S2Br2 found was compatible with the expected theoretical calculation. For an application, all of these three sensors showed excellent colorimetric specific selectivity and high sensitivity for Cu2+ in acetonitrile/water binary solutions, so only A was selected for further studies towards sensitivity. When Cu2+ was added to the solution of A, a dramatic color change from yellow to green, while other cations Fe2+, Zn2+, Ni2+, Co2+, Cr3+ and Mn2+ did not interfere with the recognition process for Cu2+. The detection limit of the sensor C toward Cu2+ was 1.15 x 10-5 M, which is less sensitive that sensor A and B with a detection limit of 6.2 x 10-6 M and 1.5 x 10-6 M respectively. This indicated that the sensor A and B might be useful as an efficient chemical sensor.

  2. Synthesis and Crystal Structure of [Copper(1,10-phenanthroline)2(pyridine)]perchlorates

    Institute of Scientific and Technical Information of China (English)

    牛德仲; 路再生; 马恒俊; 孙柏旺

    2001-01-01

    The complex [Cu(phen)2py](ClO4)2 was obtained by the reaction of 1,10-phenanthroline with Cu(C1O4)2·6H2O in water and by recrystallization from pyridine. A single-crystal X-ray study shows that the complex is a square pyramidal arrangement of five nitrogen atoms from the two 1,10-phenanthroline ligands and one pyridine ligand, respectively.The compound is orthorhombic, C29H21N5C12O8Cu, Mr = 701.958, with space group Pbcn,α = 29.9593(3), b = 16.1240(3), c = 11.9183(6)A, V= 5757.3(3)A3, Z = 8, Dc= 1.409g/cm3,μ =1.121 mm-1, F(000) = 2465, R = 0.0539, Rw = 0.1380 for 4293 reflections with I>2 σ(I). The bond lengths of Cu(1)-N(1), Cu(1)-N(2), Cu(1)-N(3) and Cu(1)-N(4) are 2.223(3),2.017(3), 2.013(3) and 2.038(3) A, respectively. The distance from copper to pyridine N(5) is 2.012(3) A. The angles N(2)-Cu(1)-N(3) and N(4)-Cu(1)-N(5) are 176.1(1)°and 160.9(1)°,respectively. The angles between axial position nitrogen atom N(1) and four square position nitrogen atoms N(2), N(3), N(4), N(5) are 79.3(1), 98.3(1), (1),108.4(1)°,respectively.

  3. Tramadol and Fentanyl and fentanyl Anesthesia Intravenous Postoperative Analgesia%曲马多复合芬太尼与芬太尼全麻术后静脉镇痛的比较

    Institute of Scientific and Technical Information of China (English)

    木也塞尔•艾买提; 热汗姑丽•台外库力

    2012-01-01

      目的探讨曲马多符合芬太尼治疗全麻术后静脉镇痛疗效。方法随机选择我院全麻手术,ASA 麻醉分级为1~2级患者87名,分成 A、B 两组,A 组31例,为对照组,行单独芬太尼注射;B 组56例,为治疗组,行曲马多复合芬太尼注射。结果 B 组3h、5h、11h、21h 呼吸频率高于 A 组,舒适评分高于 A 组,Ramsay 镇静评分高于 B 组,恶心、呕吐等不良反应发生率低于 B 组。结论曲马多复合芬太尼进行全麻术后静脉镇痛,具有较好的效果,不良反应发生率低。%  Objective Explore the tramadol in line with the intravenous analgesic effect of fentanyl treatment after general anesthesia. Methods Randomly selected hospital surgery under general anesthesia, the ASA anesthesia grade 1 to 2 patients of 87, divided into two groups (A, B),31 cases of group A, the control group, the line alone fentanyl injection; Group B 56 cases, in order totreatment group, the line tramadol fentanyl injection. Results Group B 3h,5h,11h,21h respiratory rate higher than Group A, the comfortable score higher than Group A, pain intensity was lower than group B, incidence of nausea, vomiting and other adverse reactions was lower than that in B group. Conclusion Tramadol fentanyl intravenous analgesia after general anesthesia, with good results and fewer adverse reactions.

  4. Phylogenetic Analysis of Enteroaggregative Escherichia coli (EAEC) Isolates from Japan Reveals Emergence of CTX-M-14-Producing EAEC O25:H4 Clones Related to Sequence Type 131.

    Science.gov (United States)

    Imuta, Naoko; Ooka, Tadasuke; Seto, Kazuko; Kawahara, Ryuji; Koriyama, Toyoyasu; Kojyo, Tsuyoshi; Iguchi, Atsushi; Tokuda, Koichi; Kawamura, Hideki; Yoshiie, Kiyotaka; Ogura, Yoshitoshi; Hayashi, Tetsuya; Nishi, Junichiro

    2016-08-01

    Enteroaggregative Escherichia coli (EAEC) causes acute or persistent diarrhea. The aggR gene is widely used as a marker for typical EAEC. The heterogeneity of EAEC is well known; however, there are few reports on the phylogenetic relationships of EAEC. Recently, CTX-M extended-spectrum β-lactamase (ESBL)-producing EAEC strains have been reported worldwide. To characterize EAEC strains in Japan, we investigated the population structure of EAEC. A total of 167 aggR-positive strains isolated from stool specimens from diarrheal patients in Kagoshima (139 strains) and Osaka (28 strains), Japan, between 1992 and 2010 were examined for the prevalence of EAEC virulence markers, the blaCTX-M gene, and the capacity to form biofilms. Multilocus sequence typing was also conducted. EAEC strains were widely distributed across four major E. coli phylogroups. Strains of O111:H21/clonal group 40 (CG40) (30 strains), O126:H27/CG200 (13 strains), and O86a:H27/CG3570 (11 strains) in phylogroup B1 are the historical EAEC clones in Japan, and they exhibited strong biofilm formation. Twenty-nine strains of EAEC O25:H4/CG131 were identified in phylogroup B2, 79% of which produced CTX-M-14. This clone has emerged since 2003. The clone harbored plasmid-encoded EAEC virulence genes but not chromosomal virulence genes and had lower biofilm-forming capacity than historical EAEC strains. This clone most likely emerged from a pandemic uropathogenic O25:H4/sequence type 131 clone by acquiring an EAEC virulence plasmid from canonical EAEC. Surveillance of the horizontal transfer of both virulence and ESBL genes among E. coli strains is important for preventing a worldwide increase in antimicrobial drug resistance.

  5. ALMA Observations of Orion Source I at 350 and 660 GHz

    Science.gov (United States)

    Plambeck, R. L.; Wright, M. C. H.

    2016-12-01

    Orion Source I (“SrcI”) is the protostar at the center of the Kleinmann-Low Nebula. ALMA observations of SrcI with 0.″2 angular resolution were made at 350 and 660 GHz to search for the H26α and H21α hydrogen recombination lines and to measure the continuum flux densities. The recombination lines were not detected, ruling out the possibility that SrcI is a hypercompact H ii region. The deconvolved size of the continuum source is approximately 0.″23 × 0.″07 (˜100 × 30 au); it is interpreted as a disk viewed almost edge-on. Optically thick thermal emission from ˜500 K dust is the most plausible source of the continuum, even at frequencies as low as 43 GHz; the disk mass is most likely in the range 0.02-0.2 {M}⊙ . A rich spectrum of molecular lines is detected, mostly from sulfur- and silicon-rich molecules like SO, SO2, and SiS, but also including vibrationally excited CO and several unidentified transitions. Lines with upper energy levels {E}{{U}}\\gt 500 K appear in emission and are symmetric about the source’s LSR velocity of 5 {km} {{{s}}}-1, while lines with {E}{{U}}\\lt 500 K appear as blueshifted absorption features against the continuum, indicating that they originate in outflowing gas. The emission lines exhibit a velocity gradient along the major axis of the disk that is consistent with rotation around a 5-7 {M}⊙ central object. The relatively low mass of SrcI and the existence of a 100 au disk around it are difficult to reconcile with the model in which SrcI and the nearby Becklin-Neugebauer Object were ejected from a multiple system 500 years ago.

  6. Different molecular conformations co-exist in each of three 2-aryl-N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)acetamides: hydrogen bonding in zero, one and two dimensions.

    Science.gov (United States)

    Narayana, Badiadka; Yathirajan, Hemmige S; Rathore, Ravindranath S; Glidewell, Christopher

    2016-09-01

    4-Antipyrine [4-amino-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one] and its derivatives exhibit a range of biological activities, including analgesic, antibacterial and anti-inflammatory, and new examples are always of potential interest and value. 2-(4-Chlorophenyl)-N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)acetamide, C19H18ClN3O2, (I), crystallizes with Z' = 2 in the space group P\\overline{1}, whereas its positional isomer 2-(2-chlorophenyl)-N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)acetamide, (II), crystallizes with Z' = 1 in the space group C2/c; the molecules of (II) are disordered over two sets of atomic sites having occupancies of 0.6020 (18) and 0.3980 (18). The two independent molecules of (I) adopt different molecular conformations, as do the two disorder components in (II), where the 2-chlorophenyl substituents adopt different orientations. The molecules of (I) are linked by a combination of N-H...O and C-H...O hydrogen bonds to form centrosymmetric four-molecule aggregates, while those of (II) are linked by the same types of hydrogen bonds forming sheets. The related compound N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-2-(3-methoxyphenyl)acetamide, C20H21N3O3, (III), is isomorphous with (I) but not strictly isostructural; again the two independent molecules adopt different molecular conformations, and the molecules are linked by N-H...O and C-H...O hydrogen bonds to form ribbons. Comparisons are made with some related structures, indicating that a hydrogen-bonded R2(2)(10) ring is the common structural motif.

  7. A comparative haematological analysis of Asian Elephants Elephas maximus Linnaeus, 1758 (Mammalia: Proboscidea: Elephantidae managed under different captive conditions in Sri Lanka

    Directory of Open Access Journals (Sweden)

    R.K.D. Mel

    2014-07-01

    Full Text Available Haematological parameters were assessed from elephants of three institutions in Sri Lanka with different captive conditions, in order to evaluate if different captive conditions influence the physiology of the animals. The institutions were: The National Zoological Gardens (NZG, where elephants live a comparatively sedentary lifestyle, Pinnawala Elephant Orphanage (PEO, where elephants are allowed to walk and engage in intra-specific behaviours, and Millennium Elephant Foundation (MEF, where the elephants are used for tourist rides. Four adult females were examined from the NZG, while only two males and two females could be examined from PEO and MEF respectively. All animals were sampled on four consecutive days. Blood glucose levels, total white blood cells (WBC, red blood cells (RBC, packed cell volume (PCV, mean corpuscular volume (MCV and differential white blood cell counts were carried out. Certain blood parameters of the elephants from NZG differed significantly from the parameters of the elephants from PEO and MEF. These were, the total WBC counts (Kruskal-Wallis, H=21.92, 2d.f., P=0.000, the lymphocyte count (Kruskal-Wallis, H=16.40, 2d.f., P=0.00 and the Neutrophil: Lymphocyte ratios (Kruskal-Wallis , H=14.58, 2d.f., P less than 0.05. PCV , blood glucose levels and monocyte counts were also shown to be significantly different among the three groups (Kruskal-Wallis P less than 0.000. We suggest that differences in the stress levels associated with the different management methods might influence these haematological values.

  8. Unveiling the Milky Way: A New Technique for Determining the Optical Color and Luminosity of Our Galaxy

    Science.gov (United States)

    Licquia, Timothy C.; Newman, Jeffrey A.; Brinchmann, Jarle

    2015-08-01

    We demonstrate a new statistical method of determining the global photometric properties of the Milky Way (MW) to an unprecedented degree of accuracy, allowing our Galaxy to be compared directly to objects measured in extragalactic surveys. Capitalizing on the high-quality imaging and spectroscopy data set from the Sloan Digital Sky Survey (SDSS), we exploit the inherent dependence of galaxies’ luminosities and colors on their total stellar mass, {{{M}}}\\star , and star formation rate (SFR), {\\dot{{{M}}}}\\star , by selecting a sample of Milky Way analog galaxies designed to reproduce the best Galactic {{{M}}}\\star and {\\dot{{{M}}}}\\star measurements, including all measurement uncertainties. Making the Copernican assumption that the MW is not extraordinary among galaxies of similar stellar mass and SFR, we then analyze the photometric properties of this matched sample, constraining the characteristics of our Galaxy without suffering interference from interstellar dust. We explore a variety of potential systematic errors that could affect this method, and find that they are subdominant to random uncertainties. We present both SDSS ugriz absolute magnitudes and colors in both rest-frame z = 0 and z = 0.1 passbands for the MW, which are in agreement with previous estimates but can have up to ˜3× lower errors. We find the MW to have absolute magnitude {}0{M}r-5{log}h=-{21.00}-0.37+0.38 and integrated color {}0(g-r)={0.682}-0.056+0.066, indicating that it may belong to the green-valley region in color-magnitude space and ranking it among the brightest and reddest of spiral galaxies. We also present new estimates of global stellar mass-to-light ratios for our Galaxy. This work will help relate our in-depth understanding of the Galaxy to studies of more distant objects.

  9. An Unprecedented 2D 4f-3d-5d Multimetal-lsonicotinic Acid Complex: Synthesis, Structural Characterization and Magnetic Properties

    Institute of Scientific and Technical Information of China (English)

    CHEN Wen-Tong; ZENG Xi-Rui; LIU Dong-Sheng; YING Shao-Ming; LIU Jiu-Hui

    2008-01-01

    A novel heterometallic metal-isonicotinic acid inorganic-organic hybrid complex [Zno.5(H2O)]{(Hg2C5)[Er(C6NO2H4)3(H2O)2]}(HgCl2)·0.5CH3OH·0.5H2O (1) has been successfully synthesized via a hydrothermal reaction and structurally characterized by single-crystal X-ray diffraction.Complex 1 crystallizes in the space group C2/c of the monoclinic system with eight formula units in a cell:a =34.165(4)A,b=9.4692(8)A,c=24.575(3)A,,β=115.090(5)°,V=7200(1) A3,C18.50H21Cl7ErHg3N3Ol0Zn0.50,Mr=1495.25,Dc=2.759 g/cm3,T=293(2) K,μ(Mo Ka)=15.954 mm-1,F(000)=5400 and R1/wR2=O.0561/0.0909 for 3157 observed reflections [I>2σ(I)]and 6468 unique reflections.Complex 1 is characteristic of a novel 2D { (Hg2Cl5)[Er(C6NO2H4)3(H2O)2]} layered structure constructed from the [Er(C6NO2H4)3(H2O)2]chains interconnected by the Hg2Clˉ5 linkers.The 2D {(Hg2Cl5)[Er(C6NO2H4)3(H2O)2]} layers,mercury chloride and the lattice water molecules are held together via hydrogen bonds to form a three-dimensional framework with the methanol molecules and the hydrated zinc ions located in the cavities.The magnetic properties show that complex 1 exhibits antiferromagnetic-like interactions.

  10. Identification of Ganglioside GM3 Molecular Species in Human Serum Associated with Risk Factors of Metabolic Syndrome.

    Directory of Open Access Journals (Sweden)

    Lucas Veillon

    Full Text Available Serum GM3 molecular species were quantified in 125 Japanese residents using tandem mass spectrometry multiple reaction monitoring. Individuals were categorized by the presence or absence of metabolic disease risk factors including visceral fat accumulation, hyperglycemia and dyslipidemia. A total of 23 GM3 molecular species were measured, of these, eight were found to be significantly elevated in individuals with visceral fat accumulation and metabolic disease, defined as the presence of hyperglycemia and dyslipidemia. All of the GM3 molecular species were composed of the sphingoid base sphingosine (d18:1 (Δ4 and, interestingly, six of the eight elevated GM3 molecular species contained a hydroxylated ceramide moiety. The hydroxylated GM3 species were, in order of decreasing abundance, d18:1-h24:0 ≈ d18:1-h24:1 > d18:1-h22:0 » d18:1-h20:0 > d18:1-h21:0 > d18:1-h18:1. Univariate and multiple linear regression analyses were conducted using a number of clinical health variables associated with obesity, type 2 diabetes, metabolic disease, atherosclerosis and hypertension. GM3(d18:1-h24:1 was identified as the best candidate for metabolic screening, proving to be significantly correlated with intima-media thickness, used for the detection of atherosclerotic disease in humans, and a number of metabolic disease risk factors including autotaxin, LDL-c and homeostatic model assessment insulin resistance (HOMA-IR.

  11. Studies on the hydrothermal modifications of new cocoyam (Xanthosoma sagittifolium) starch.

    Science.gov (United States)

    Lawal, Olayide S

    2005-12-30

    Native new cocoyam starch (nNCS) was subjected to annealing (aNCS) and heat moisture treatment at 18% moisture level (h18NCS), 21% moisture level (h21NCS), 24% moisture level (h24NCS) and 27% moisture level (h27NCS) as hydrothermal treatments. Scanning electron and light microscopy revealed round and polygonal shapes with sizes ranging from 15 to 40 microm for native and modified starches. nNCS showed "A" pattern X-ray diffraction and no significant differences were observed in the X-ray pattern of the modified starches. Swelling power and solubility reduced following heat moisture treatment. At all pH studied (2-12), unmodified new cocoyam starch exhibited higher swelling capacity and solubility than the modified derivatives. Hydrothermal modifications improved water absorption capacity but reduced oil absorption capacity. Pasting temperature of native starch shifted to higher values following annealing and heat moisture treatment. Hot paste viscosity (Hv), viscosity after 30 min holding at 95 degrees C (Hv30) and cold paste viscosity (Cv) reduced after annealing and heat moisture treatment. The result also indicates that hydrothermal treatments reduced the tendency for setback. As the number of days of storage of starch paste increased from 1 to 10, light transmittance of all the starches reduced but marked reduction of light transmittance was observed in native starch. DSC studies revealed increase in gelatinization temperature following annealing and heat moisture treatment. Starch hydrothermal modifications reduced retrogradation as enthalpies of regelatinization reduced following modifications. The regelatinization peak in the second day scanning shifted to lower temperature than the gelatinization peak in first run heating DSC curve for all samples. The regelatinization peak also became larger and shifted to higher temperature range when the storage days increased from 2 to 7.

  12. Crystal structures, lattice potential energies, and thermochemical properties of crystalline compounds (1-C(n)H(2n+1)NH3)2ZnCl4(s) (n = 8, 10, 12, and 13).

    Science.gov (United States)

    Liu, Yupu; Di, Youying; He, Donghua; Zhou, Qian; Dou, Jianmin

    2011-11-01

    As part of our ongoing project involving the study of (1-C(n)H(2n+1)NH(3))(2)MCl(4)(s) (where M is a divalent metal ion and n = 8-18), we have synthesized the compounds (1-C(n)H(2n+1)NH(3))(2)ZnCl(4)(s) (n = 8, 10, 12, and 13), and the details of the structures are reported herein. All of the compounds were crystallized in the monoclinic form with the space group P2(1)/n for (1-C(8)H(17)NH(3))(2)ZnCl(4)(s), P21/c for (1-C(10)H(21)NH(3))(2)ZnCl(4)(s), P2(1)/c for (1-C(12)H(25)NH(3))(2)ZnCl(4)(s), and P2(1)/m for (1-C(13)H(27)NH(3))(2)ZnCl(4)(s). The lattice potential energies and ionic volumes of the cations and the common anion of the title compounds were obtained from crystallographic data. Molar enthalpies of dissolution of the four compounds at various molalities were measured at 298.15 K in the double-distilled water. According to Pitzer's theory, molar enthalpies of dissolution of the title compounds at infinite dilution were obtained. Finally, using the values of molar enthalpies of dissolution at infinite dilution (Δ(s)H(m)(∞)) and other auxiliary thermodynamic data, the enthalpy change of the dissociation of [ZnCl(4)](2-)(g) for the reaction [ZnCl(4)](2-)(g)→ Zn(2+)(g) + 4Cl(-)(g) was obtained, and then the hydration enthalpies of cations were calculated by designing a thermochemical cycle.

  13. Protection against Shiga-Toxigenic Escherichia coli by Non-Genetically Modified Organism Receptor Mimic Bacterial Ghosts.

    Science.gov (United States)

    Paton, Adrienne W; Chen, Austen Y; Wang, Hui; McAllister, Lauren J; Höggerl, Florian; Mayr, Ulrike Beate; Shewell, Lucy K; Jennings, Michael P; Morona, Renato; Lubitz, Werner; Paton, James C

    2015-09-01

    Shiga-toxigenic Escherichia coli (STEC) causes severe gastrointestinal infections in humans that may lead to life-threatening systemic sequelae, such as the hemolytic uremic syndrome (HUS). Rapid diagnosis of STEC infection early in the course of disease opens a window of opportunity for therapeutic intervention, for example, by administration of agents that neutralize Shiga toxin (Stx) in the gut lumen. We previously developed a recombinant bacterium that expresses a mimic of the Stx receptor globotriaosyl ceramide (Gb3) on its surface through modification of the lipopolysaccharide (A. W. Paton, R. Morona, and J. C. Paton, Nat Med 6:265-270, 2000, http://dx.doi.org/10.1038/73111). This construct was highly efficacious in vivo, protecting mice from otherwise fatal STEC disease, but the fact that it is a genetically modified organism (GMO) has been a barrier to clinical development. In the present study, we have overcome this issue by development of Gb3 receptor mimic bacterial ghosts (BGs) that are not classified as GMOs. Gb3-BGs neutralized Stx1 and Stx2 in vitro with high efficiency, whereas alternative Gb3-expressing non-GMO subbacterial particles (minicells and outer membrane blebs) were ineffective. Gb3-BGs were highly efficacious in a murine model of STEC disease. All mice (10/10) treated with Gb3-BGs survived challenge with a highly virulent O113:H21 STEC strain and showed no pathological signs of renal injury. In contrast, 6/10 mice treated with control BGs succumbed to STEC challenge, and survivors exhibited significant weight loss, neutrophilia, and histopathological evidence of renal damage. Thus, Gb3-BGs offer a non-GMO approach to treatment of STEC infection in humans, particularly in an outbreak setting.

  14. [μ2-Bis(diphenylphosphanylmethane][μ3-bis(diphenylphosphanylmethyl]trichloridotetragold(I tetrahydrofuran disolvate

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    Huan-Huan Wang

    2011-02-01

    Full Text Available The title tetranuclear complex, [Au4(C25H21P2Cl3(C25H22P2]·2C4H8O, features two non-equivalent Ph2PCPPh2 fragments, one of which represents the `complete' molecule (with two H atoms at the central C atom; each of the two P atoms of this molecule is coordinated by an Au atom [Au—P = 2.2256 (13 and 2.2710 (13 Å], and these two Au atoms form an Au—Au bond [3.2945 (3 Å], thus closing the five-membered Au2P2C ring. The first of these Au atoms has a terminal chlorido ligand [Au—Cl = 2.2806 (12 Å], whereas the second Au atom forms a covalent bond with the central C atom of the bis(diphenylphosphinomethyl group [Au—C = 2.114 (5 Å]; the latter group in turn coordinates with its P atoms the gold atoms of the Cl–Au–Au–Cl group [Au—P = 2.2356 (13 and 2.2338 (13, Au—Au = 3.3177 (3, Au—Cl = 2.3091 (12 and 2.2950 (13 Å], thus closing the second Au2P2C ring. The two such rings have different chemical functions, but both exhibit envelope conformations. However, the first (with different substituents at the Au atoms is non-symmetrical with one of the P atoms in the flap position of the envelope; the other one has a conformation with mirror symmetry, and the gold-substituted C atom is displaced by 0.740 (5 Å from the almost exactly planar (r.m.s. deviation = 0.0038 Å Au2P2 group.

  15. AD-MSCs alleviate hyperglycemia through promoting hepatic glycolysis in type 2 diabetic rats

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    Min XIE

    2016-08-01

    Full Text Available Objective  To evaluate the temporary hypoglycemic effect of adipose mesenchymal stem cells (AD-MSCs on type 2 diabetic rats, and further discuss the mechanisms of AD-MSCs regulating blood glucose through hepatic glycometabolism. Methods  The type 2 diabetic rat model was established by intraperitoneal injection of a single small dose of streptozotocin (STZ, 25mg/kg after a high-fat diet for 8 weeks. The content of blood glucose was determined by tail vein bleeding at indicated time points (0h, 3h, 6h, 12h, 24h after infusion of AD-MSCs, concurrently the rats were executed and the liver tissues were collected (diabetes group, n=5, normal group, n=3 for detecting the mRNA and protein expressions of glucokinase (GK, pyruvate kinase (PK and phosphofructokinase (PFK (the key enzyme of glycolysis by real-time qPCR and Western blotting. Results  The infusion of AD-MSCs significantly decreased blood glucose in a short period [30.55±1.49mmol/L(0h, 18.90±0.85mmol/ L(3h, 23.70±1.13mmol/L(6h, 21.90±1.00mmol/L(12h, respectively]. PCR results showed that the expressions of GK and PFK increased in the liver tissue of type 2 diabetic rats 3h after AD-MSCs infusion, and the expression of PK increased significantly 6h after AD-MSCs infusion (P<0.05. Conclusion  AD-MSCs can ameliorate hyperglycemia rapidly through enhancing liver glycolysis in type 2 diabetic rats. DOI: 10.11855/j.issn.0577-7402.2016.07.04

  16. η Carinae Baby Homunculus uncovered by ALMA

    Energy Technology Data Exchange (ETDEWEB)

    Abraham, Zulema; Beaklini, Pedro P. B. [Instituto de Astronomia, Geofísica e Ciências Atmosféricas, Universidade de São Paulo, R. do Matão 1226, Cidade Universitária, CEP 05508-900 São Paulo, SP (Brazil); Falceta-Gonçalves, Diego, E-mail: zulema.abraham@iag.usp.br [Escola de Artes, Ciências e Humanidades, Universidade de São Paulo, R. Arlindo Bettio 1000, 03828-000 São Paulo, SP (Brazil)

    2014-08-20

    We report observations of η Carinae obtained with ALMA in the continuum of 100, 230, 280, and 660 GHz in 2012 November, with a resolution that varied from 2.''88 to 0.''45 for the lower and higher frequencies, respectively. The source is not resolved, even at the highest frequency; its spectrum is characteristic of thermal bremsstrahlung of a compact source, but different from the spectrum of optically thin wind. The recombination lines H42α, He42α, H40α, He40α, H50β, H28α, He28α, H21α, and He21α were also detected, and their intensities reveal non-local thermodynamic equilibrium effects. We found that the line profiles could only be fit by an expanding shell of dense and ionized gas, which produces a slow shock in the surroundings of η Carinae. Combined with fittings to the continuum, we were able to constrain the shell size, radius, density, temperature, and velocity. The detection of the He recombination lines is compatible with the high-temperature gas and requires a high-energy ionizing photon flux, which must be provided by the companion star. The mass-loss rate and wind velocity, necessary to explain the formation of the shell, are compatible with an luminous blue variable eruption. The position, velocity, and physical parameters of the shell coincide with those of the Weigelt blobs. The dynamics found for the expanding shell correspond to matter ejected by η Carinae in 1941 in an event similar to that which formed the Little Homunculus; for that reason, we called the new ejecta the 'Baby Homunculus'.

  17. Synthesis and Crystal Structure of Rctt-1-(2-benzoxazolyl)-2-(4-chlorophenyl)-4-phenyl-3-(4-pyridinyl) cyclobutane

    Institute of Scientific and Technical Information of China (English)

    庄俊鹏; 张文勤

    2003-01-01

    The title compound (C28H21ClN2O, Mr = 436.92) was synthesized by the cross- photodimerization of (E)-2-(2-phenylethenyl)benzoxazole and (E)-4-[2-(4-chlorophenyl)ethenyl]- pyridine in sulfuric acid solution. Its molecular structure has been unequivocally determined by X-ray crystallography. The title compound belongs to triclinic system, space group Pī with cell parameters: a = 9.648(3), b = 10.458(4), c = 12.106(4) A。, r = 89.089(7), a = 75.644(6), B = 68.441(7)o, V = 1096.7(7) A。3, Z = 2, Dc = 1.323 g/cm3, F(000) = 456 and ((MoKa) = 0.198 mm-1. The final R and wR are 0.0627 and 0.1285, respectively for 1737 observed reflections with I > 2((I). S = 0.921 and (Δ/max = 0.001. The cyclobutane ring has a puckered conformation with four different aryl groups substituted on each carbon atom. The dihedral angles of the cyclobutane ring are 20.2 and 20.6o. The bond distances of the cyclobutane ring are 1.541, 1.555, 1.560 and 1.563 A。, respectively, which are slightly longer than that of the normal C-C single bond. The title compound is the only cross-dimer and its two heteroaryl groups are situated at the trans-1,3 position of the cyclobutane ring, revealing that the cross-photodimerization proceeds in a head-to-tail pattern with high stereo-selectivity.

  18. Synthesis and Crystal Structure of Rctt—1—(2—benzoxaolyl)—2—(4—chlorophenyl)—4—phenyl—3—(4—pyridinyl)cyclobutane

    Institute of Scientific and Technical Information of China (English)

    ZHUANGJun-Peng; ZHANGWen-Qin

    2003-01-01

    The title compound (C28H21C1N2O,Mr=436.92) was synthesized by the cross-photodimerization of (E)-2-(2-phenylethenyl) benzoxazole and (E)-4-[2-(4-cholrophenyl)ethenyl]-pyridine in sulfuric acid solution.Its molecular structure has been unequivocally detemined by X-ray Crystallography,The title compound belongs to triclinic system,space group P-↑1 with cell parameters:a=9.648(3),b=0.458(4),c=12.1064(4)°↑A,α=89.089(7),β=75.644(6),γ=68.441(7)°,V=1096.7(7)°↑A3,Z=2,Dc=1.323 g/cm3,F(000)=456 and μ(Mokα)=0.198mm-1,The final R and wR are 0.0627 and 0.1285,respectively for 1737 observed refections with I>2σ(I),S=0.921 and (△/σ)max=0.001,The cyclobutane ring has a puckered conformation with four different aryl groups substituted on each carbon atom.The dihedral angles of the cyclobutane ring are 20.2 and 20.6°.The bond distances of the cyclobutane ring are 1.541,1.555,1.560 and 1.563°↑A,respectively,which are slightly longer than that of the normal C-C single bond.The title compound is the only cross-dimer and its two heteroaryl groups are situated at the trans-1,3 position of the cyclobutane ring,revealing that the cross-photodimerization proceeds in a head-to-tail pattern with high stereo-selectivity.

  19. Recalcitrance and degradation of petroleum biomarkers upon abiotic and biotic natural weathering of Deepwater Horizon oil.

    Science.gov (United States)

    Aeppli, Christoph; Nelson, Robert K; Radović, Jagoš R; Carmichael, Catherine A; Valentine, David L; Reddy, Christopher M

    2014-06-17

    Petroleum biomarkers such as hopanoids, steranes, and triaromatic steroids (TAS) are commonly used to investigate the source and fate of petroleum hydrocarbons in the environment based on the premise that these compounds are resistant to biotic and abiotic degradation. To test the validity of this premise in the context of the Deepwater Horizon disaster, we investigated changes to these biomarkers as induced by natural weathering of crude oil discharged from the Macondo Well (MW). For surface slicks collected from May to June in 2010, and other oiled samples collected on beaches in the northern Gulf of Mexico from July 2010 until August 2012, hopanoids with up to 31 carbons as well as steranes and diasteranes were not systematically affected by weathering processes. In contrast, TAS and C32- to C35-homohopanes were depleted in all samples relative to 17α(H),21β(H)-hopane (C30-hopane). Compared to MW oil, C35-homohopanes and TAS were depleted by 18 ± 10% and 36 ± 20%, respectively, in surface slicks collected from May to June 2010, and by 37 ± 9% and 67 ± 10%, respectively, in samples collected along beaches from April 2011 through August 2012. Based on patterns of relative losses of individual compounds, we hypothesize biodegradation and photooxidation as main degradation processes for homohopanes and TAS, respectively. This study highlights that (i) TAS and homohopanes can be degraded within several years following an oil spill, (ii) the use of homohopanes and TAS for oil spill forensics must account for degradation, and (iii) these compounds provide a window to parse biodegradation and photooxidation during advanced stages of oil weathering.

  20. Biological marker distribution and significance in oils and rocks of the Monterey Formation, California

    Science.gov (United States)

    Curiale, Joseph A.; Cameron, Douglas; Davis, Dean V.

    1985-01-01

    The biological marker distributions of several oils, core extracts and solid bitumens of the Monterey Formation of California have been studied. Sterane, terpane and monoaromatic steroid hydrocarbons were analyzed in samples from the San Joaquin, Los Angeles, Ventura and Santa Maria Basins. The sterane patterns of both oils and extracts are characterized by (a) low relative concentrations of diasteranes, (b) low 20S/20R-5α,14α,17α-ethylcholestane ratios, (c) relatively high concentrations of cholestane ( vs. methyl- and ethylcholestane) isomers. San Joaquin Basin samples contain significant amounts of the 5β isomer, which is generally absent in samples from other basins. The carbon number distribution of 5α,14α,17α,20R steranes is similar for all oils, regardless of API gravity, depth or basin location, and is suggestive of open marine depositional conditions for the source material involved. 17α(H),l8α(H),21β(H)-28,30-Bisnorhopane is present in almost all samples. Certain San Joaquin Basin oils and extracts contain (a) a series of 25-nor hopanes, including 25,28,30-trisnorhopane, (b) a distinctive monoaromatic steroid hydrocarbon distribution, (c) an aliphatic hydrocarbon fraction devoid of n-paraffins. Biological marker characteristics suggest that the Monterey oils examined originated early in the maturational sequence, from elastics-poor source material. API gravities of the Monterey Formation oils examined vary monotonically with (a) bisnorhopane/hopane ratios, (b) aromatized/regular sterane ratios and (c) the concentration of monoaromatized steranes relative to terpanes and regular steranes. These oil gravity correlations exist regardless of sample depth or basin location.

  1. The Effect of Transdermal Scopolamine for the Prevention of Postoperative Nausea and Vomiting

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    Maria A. Antor

    2014-04-01

    Full Text Available Postoperative nausea and vomiting is one of the most common and undesirable complaints recorded in as many as 70%-80% of high-risk surgical patients. The current prophylactic therapy recommendations for PONV management stated in the Society of Ambulatory Anesthesia guidelines should start with monotherapy and patients at moderate to high risk, a combination of antiemetic medication should be considered. Consequently, if rescue medication is required, the antiemetic drug chosen should be from a different therapeutic class and administration mode than the drug used for prophylaxis. The guidelines restrict the use of dexamethasone, transdermal scopolamine, aprepitant, and palonosetron as rescue medication 6 hours after surgery. In an effort to find a safer and reliable therapy for postoperative nausea and vomiting, new drugs with antiemetic properties and minimal side effects are needed, and scopolamine may be considered an effective alternative. Scopolamine is a belladonna alkaloid, α-(hydroxymethyl benzene acetic acid 9-methyl-3-oxa-9-azatricyclo non-7-yl ester, acting as a nonselective muscarinic antagonist and producing both peripheral antimuscarinic and central sedative, antiemetic, and amnestic effects. The empirical formula is C17H21NO4 and its structural formula is a tertiary amine L-(2-scopolamine (tropic acid ester with scopine; MW = 303.4. Scopolamine became the first drug commercially available as a transdermal therapeutic system used for extended continuous drug delivery during 72 hours. Clinical trials with transdermal scopolamine have consistently demonstrated its safety and efficacy in postoperative nausea and vomiting. Thus, scopolamine is a promising candidate for the management of postoperative nausea and vomiting in adults as a first line monotherapy or in combination with other drugs. In addition, transdermal scopolamine might be helpful in preventing postoperative discharge nausea and vomiting owing to its long

  2. The clinical observation of three-dimensional conformal radiotherapy combined with FOLFOX chemotherapy for rectal cancer of postoperative local recurrence

    Institute of Scientific and Technical Information of China (English)

    Yeqin Zhou; Mi Liu; Daiyuan Ma; Tao Ren; Xiaojie Ma; Xianfu Li; Bangxian Tan

    2012-01-01

    Objective: The aim of this study was to explore the three-dimensional conformal radiotherapy combined with FOLFOX scheme chemotherapy in the treatment of postoperative recurrence of rectal cancer. Methods: Sixty-eight cases of recurrent rectal cancer were divided randomly into two groups: 34 cases of conformal radiotherapy plus FOLFOX chemotherapy group (experiment group) and 34 cases of conformal radiotherapy (control group). After 6 MvX line with three-dimensional conformal radiotherapy technologies for recurrent lesions and pelvic cavity around subclinical lymphatic drainage radiotherapy after radiotherapy to DT 40 Gy to reposit was made use of between both groups, experiment group was made the new treatment plan to continue to irradiate to 50 Gy, and then Shrinkage GTV was pushed quantity in the field 66 Gy. Researchers took chemotherapy in the first week and the fourth week after radiotherapy, with 5-fluorouracil 500 mg/m2, calcium leucovorin 200 mg, d1-5 with intravenous drip, Oxaliplatin 130 mg/m2 and d1 with intravenous drip 2 h, 21 days was one cycle. Kaplan-Meier method was used for survival analysis. Results: The survival rates for 1, 2 and 3 years for experiment group and control group were 88.2%, 64.7%, 47.1% and 66.7%, 38.2%, 29.4% (P = 0.03), the 2-year rate of distant metastases was 32.4% and 58.8% (P = 0.032) respectively. The median survival time was 33 and 20 months respectively. There were some side effects between the groups, but there was no statistical difference. Conclusion: Three-dimensional conformal radiotherapy plus FOLFOX chemotherapy can be considered as a safe and effective approach to treat rectal cancer patients of postoperative recurrence, and can improve the survival rates of patients and reduce distant metastasis rate obviously and make the acute adverse reaction rate insignificantly.

  3. Photometric redshifts and clustering of emission line galaxies selected jointly by DES and eBOSS

    Energy Technology Data Exchange (ETDEWEB)

    Jouvel, S.; et al.

    2015-09-23

    We present the results of the first test plates of the extended Baryon Oscillation Spectroscopic Survey. This paper focuses on the emission line galaxies (ELG) population targetted from the Dark Energy Survey (DES) photometry. We analyse the success rate, efficiency, redshift distribution, and clustering properties of the targets. From the 9000 spectroscopic redshifts targetted, 4600 have been selected from the DES photometry. The total success rate for redshifts between 0.6 and 1.2 is 71\\% and 68\\% respectively for a bright and faint, on average more distant, samples including redshifts measured from a single strong emission line. We find a mean redshift of 0.8 and 0.87, with 15 and 13\\% of unknown redshifts respectively for the bright and faint samples. In the redshift range 0.6h < -21.0. We note that biasing is derived from the galaxy clustering relative to a model for the mass fluctuations. We investigate the quality of the DES photometric redshifts and find that the outlier fraction can be reduced using a comparison between template fitting and neural network, or using a random forest algorithm.

  4. Optimisation research of petroleum hydrocarbon biodegradation in weathered drilling wastes from waste pits.

    Science.gov (United States)

    Steliga, Teresa; Jakubowicz, Piotr; Kapusta, Piotr

    2010-12-01

    The aim of this article is to discuss the problem of drilling waste remediation. Analyses and research showed that material stored in waste pits could be classified as soil with a high level of petroleum impurities (total petroleum hydrocarbons [TPH] = 102,417-132,472 mg kg(-1) dry mass). While preparing the complex technology of soil decontamination (which included primary reclamation, basic bioremediation and inoculation with biopreparations based on indigenous bacteria and fungi), laboratory tests indicated the use of an ex-situ method was fundamental. Remediation was controlled with a chromatographic method of qualitative and quantitative determination of petroleum hydrocarbons. Based on analytical data, there was the possibility to determine the effectiveness of consecutive purifying phases. Laboratory tests, following 135 days of basic bioremediation stimulated by optimum conditions to activate the growth of indigenous micro-organisms, resulted in a decrease in the TPH content, which was in the range of 52.3-72.5%. The next phase of soil decontamination lasted 135 days and involved the use of inoculation with biopreparations based on indigenous micro-organisms and fungi. This process enabled a TPH decrease of 93.8- 94.3%. Laboratory biodegradation research was done with the use of the biomarker C30-17α(H)21β(H)-hopane to normalize analyte (TPH, Σn-C8-n-C22 and Σn-C23-n-C36) concentrations. The calculated first-order biodegradation constants enable estimation of the purification stage dynamics and the effectiveness of the applied biopreparations. Furthermore, they represent the biodegradation degree of individual n-alkanes in subsequent stages of the soil purification process.

  5. Altered electroencephalographic activity associated with changes in the sleep-wakefulness cycle of C57BL/6J mice in response to a photoperiod shortening

    Directory of Open Access Journals (Sweden)

    Stanislav Rozov

    2016-08-01

    Full Text Available AimUnder natural conditions diurnal rhythms of biological processes of the organism are synchronized with each other and to the environmental changes by means of the circadian system. Disturbances of the latter affect hormonal levels, sleep-wakefulness cycle and cognitive performance. To study mechanisms of such perturbations animal models subjected to artificial photoperiods are often used. The goal of current study was to understand the effects of circadian rhythm disruption, caused by a short light-dark cycle regime, on activity of the cerebral cortex in rodents.MethodsWe used electroencephalogram to assess the distribution of vigilance states, perform spectral analysis, and estimate the homeostatic sleep drive. In addition, we analyzed spontaneous locomotion of C57BL/6J mice under symmetric, 22-h-, 21-h-, and 20-h-long light–dark cycles using video recording and tracking methods.Results and ConclusionsWe found that shortening of photoperiod caused a significant increase of slow wave activity during non-rapid eye movement sleep suggesting an elevation of sleep pressure under such conditions. While the rhythm of spontaneous locomotion was completely entrained by all light–dark cycles tested, periodic changes in the power of the θ- and γ-frequency ranges during wakefulness gradually disappeared under 22-h- and 21-h-long light–dark cycles. This was associated with a significant increase in the θ–γ phase-amplitude during wakefulness. Our results thus provide deeper understanding of the mechanisms underlying the impairment of learning and memory retention, which is associated with disturbed circadian regulation.

  6. Physiological and behavioural responses of Gammarus pulex (Crustacea: Amphipoda) exposed to cadmium

    Energy Technology Data Exchange (ETDEWEB)

    Felten, V. [Laboratoire d' Ecotoxicologie, CEMAGREF, 3 bis quai Chauveau, CP 220, 69336 Lyon Cedex 09 (France)], E-mail: vincent.felten@univ-reims.fr; Charmantier, G. [Equipe Adaptation Ecophysiologique et Ontogenese, UMR 5119 Ecolag, Universite Montpellier II, Place E. Bataillon, 34095 Montpellier Cedex 05 (France); Mons, R. [Laboratoire d' Ecotoxicologie, CEMAGREF, 3 bis quai Chauveau, CP 220, 69336 Lyon Cedex 09 (France); Geffard, A. [Laboratoire d' Eco-toxicologie, Universite de Reims Champagne Ardenne, Faculte des Sciences, Moulin de la Housse, BP 1039, 51687 Reims Cedex 2 (France); Rousselle, P. [Laboratoire Biodiversite et Fonctionnement des Ecosystemes, Universite de Metz, Campus Bridoux, Rue du General Delestraint, 57 070 Metz (France); Coquery, M. [Laboratoire de Chimie Environnementale, CEMAGREF, 3 bis quai Chauveau, CP 220, 69336 Lyon Cedex 09 (France); Garric, J.; Geffard, O. [Laboratoire d' Ecotoxicologie, CEMAGREF, 3 bis quai Chauveau, CP 220, 69336 Lyon Cedex 09 (France)

    2008-02-18

    The aim of this study was to investigate the effects of cadmium on physiological and behavioural responses in Gammarus pulex. In a first experiment, cadmium LC50s for different times were evaluated in 264 h experiment under continuous mode of exposure (LC50{sub 96h} = 82.1 {mu}g L{sup -1}, LC50{sub 120h} = 37.1 {mu}g L{sup -1}, LC50{sub 168h} = 21.6 {mu}g L{sup -1}, LC50{sub 264h} = 10.5 {mu}g L{sup -1}). In a second experiment, the physiological and behavioural responses of the amphipod exposed to cadmium (0, 7.5 and 15 {mu}g L{sup -1}) were investigated under laboratory conditions. The mortality and the whole body cadmium concentration of organisms exposed to cadmium were significantly higher than in controls. Concerning physiological responses, cadmium exposure exerted a significant decrease on osmolality and haemolymph Ca{sup 2+} concentration, but not on haemolymph Na{sup +} and Cl{sup -} concentrations, whereas the Na{sup +}/K{sup +}-ATPase activity was significantly increased. Behavioural responses, such as feeding rate, locomotor and ventilatory activities, were significantly reduced in Cd exposed organisms. Mechanism of cadmium action and consequent energetic reallocation in favour of maintenance functions (i.e., osmoregulation) are discussed. The results of this study indicate that osmolality and locomotor activity in G. pulex could be effective ecophysiological/behavioural markers to monitor freshwater ecosystem and to assess the health of organisms.

  7. Dinâmica espaço-temporal de flebotomíneos (Diptera, Psychodidae do município de Santa Quitéria, área de cerrado do Estado do Maranhão, Brasil Spatial-temporal dynamics of phlebotomine sandflies (Diptera, Psychodidae in the municipality of Santa Quitéria, "cerrado'' area, State of Maranhão, Brazil

    Directory of Open Access Journals (Sweden)

    Alexsandra M. C. B. Martin

    Full Text Available A flutuação sazonal, a freqüência horária e a ocorrência dos flebotomíneos nos ambientes intradomiciliar, peridomiciliar e extradomiciliar (cerrado, no município de Santa Quitéria, Estado do Maranhão foram estudados. Os espécimes foram capturados entre 18 e 6 horas, de maio de 1999 a abril de 2000, com armadilhas luminosas tipo CDC. Foram coletados 4.880 espécimes de 11 espécies. A riqueza e abundância foram maiores no peridomicílio (11 espécies; 50,1% dos espécimes, seguido pelo intradomicílio (9 espécies, 34% e cerrado (7 espécies, 15,8%. Duas espécies foram encontradas na estação chuvosa, uma na estiagem e oito em ambas estações. Na estiagem foram registradas elevadas freqüências de Lutzomyia longipalpis Lutz & Neiva, 1912 (88,4%, L. evandroi Costa Lima & Antunes, 1936 (83,6%, L. lenti Mangabeira, 1938 (86% e L. shannoni Dyar, 1929 (100%, enquanto as freqüências de L. quinquefer Dyar, 1929 (100% e L. whitmani Antunes & Coutinho, 1939 (75% foram maiores no período chuvoso. Os flebotomíneos foram encontrados a noite inteira, mas os horários de maior freqüência variaram de acordo com a espécie, observando-se picos no crepúsculo vespertino e primeiras horas da noite: L. quinquefer (18 h - 19 h; L. goiana Martins, Falcão & Silva, 1962 (18 h - 21 h; L. whitmani (19 h - 21 h e L. longipalpis (20 h - 21 h e ao longo da noite e no crepúsculo matutino: L. evandroi (21 h - 23 h e 3 h - 5 h, L. longipalpis (1 h - 3 h, L. lenti (22 h - 23 h e 4 h - 5 h. A ocorrência dos flebotomíneos nos diferentes ambientes, horários e estações vem sendo acompanhada por notificações de vários casos de leishmanioses cutânea e visceral.The seasonal fluctuation, hourly frequency and occurrence of phlebotomine sandflies inside and around dwellings and in the cerrado area of the municipality of Santa Quitéria, State of Maranhão were studied. The specimens were collected between 6:00 pm and 6:00 am from May 1999 to April 2000

  8. Molecular structure of kerogens from source rocks of the Tarim Basin: A study by Py-GC-MS and methylation-Py-GC-MS

    Institute of Scientific and Technical Information of China (English)

    JIA; Wanglu; PENG; Ping'an

    2005-01-01

    Flash pyrolysis-gas chromatography-mass spectrometry (Py-GC-MS) and in situ methylation-pyrolysis-gas chromatography-mass spectrometry (methylation-Py-GC-MS) have been employed for a study of molecular structure of kerogens from source rocks of the Tarim Basin. The main products from Py-GC-MS of the Ordovician and Triassic kerogens from the Tarim Basin are n-alkanes and n-alk-1-enes which decrease in relative abundance with increased carbon number. The major products from methylation-Py-GC-MS are normal saturated fatty acid methyl esters which show maxima at C16 and C18. These aliphatic compounds are mainly from lipids of planktonic algae. Moreover, there are more abundant long-chain fatty acids (C20-C26) and normal n-alkanes and n-alk-1-enes (C15-C25) in pyrolysates of Triassic kerogens than that of Ordovician kerogens, reflecting the discrepancies in sources of the Triassic kerogens and the Ordovician kerogens. Besides these aliphatic compounds, methoxyl benzoic acid methyl esters were detected only in products from methylation-Py-GC-MS of late Ordovician kerogen TAC1-1, which possibly was the first molecular evidence for the appearance of moss or other terrestrial plants in the Tarim Basin. In addition, the relative intensity of 17β(H)-trisnorhopane17 β(H),21 α(H)-30-normoretane and 17 β(H)-moretane is lower, but 17α(H)-trisnorhopane and17 α(H)-30-norhopane is higher in the pyrolysates of the Ordovician kerogens in comparison with the pyrolysates of the Triassic kerogens. Moreover, Pr-1-ene has been detected in pyrolysates of Triassic kerogens. These differences in pyrolysates consist with maturity of kerogens. In conclusion, combination of methylation-Py-GC-MS and Py-GC-MS are useful tools to investigate the molecular structure of geomacromolecules and can be subject to type the organic matter, compare the maturity of kerogens and carry out the oil-source correlation.

  9. Balanço de energia em vinhedo de 'Niagara Rosada' Energy balance on 'Niagara Rosada' vineyard

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    José Ricardo Macedo Pezzopane

    2003-01-01

    Full Text Available O método do balanço de energia foi utilizado para caracterizar a variação horária do saldo de radiação e dos fluxos de calor latente, sensível e no solo, em vinhedo cultivado com a cultivar NiagaraRosada', conduzida no sistema de espaldeira, em Jundiaí (SP. Além disso, foram determinadas as relações entre o saldo de radiação (SR no vinhedo e a radiação solar global (RG e a partição da energia disponível ao sistema nos fluxos de calor latente (LE, sensível (H e no solo (G. Em um dia característico de período seco, o LE representou 44% do SR e o H, 48%. Em um dia chuvoso, o LE representou 86% do SR e o H, 21%. Em um dia ensolarado, após um período de chuvas, LE e H foram, respectivamente, 68% e 29% do SR. O G foi, em média, 5,7% e 1,3% do SR para as ruas mantidas capinadas e com forro, respectivamente.The energy balance method was used to characterize the hourly variation of the net radiation, latent and sensible fluxes and soil heat flux on a mature vineyard grown at Jundiaí, São Paulo, Brazil. The grapevines, cv. Niagara Rosada, in the vineyard were wrapped to trellis wires, creating compact hedgerows 2 m apart, 1.7 m height and 0.4 wide, with the foliage 1m above the soil surface. Also, the net and incoming radiation relationships and the partioning of the available energy to the system into latent and heat flux, and soil heat flux were determined for the vineyard. During a sunny day (dry period the latent heat flux was 44% of the net radiation and the sensible heat flux, 48%. However during a rainy day, the latent heat flux was 86% of the net radiation and the sensible heat flux, 21%. During a sunny day, after the occurrence of rain, the latent and sensible heat fluxes were, respectively, 68% and 29% of the net radiation. The soil heat flux was 5.7 an 1.3% of the net radiation, for bare soil and mulched rows, respectively.

  10. Thermodynamics Analysis of Cesium Adsorption on Na2Ti2O3SiO4 · 2H2O%钛硅酸钠( Na2Ti2O3SiO4·2H2O)对Cs的吸附热力学分析

    Institute of Scientific and Technical Information of China (English)

    王保柱; 张东; 石正坤; 吴涛

    2012-01-01

    钛硅酸钠(Crystalline Sillicotitanate,CST)对铯(Cs)的吸附热力学分析是研究钛硅酸钠吸附铯机理的重要途径之一.本工作通过研究不同温度下CST与不同浓度CsNO3溶液反应,测定反应前后Cs+的浓度变化,得到了一系列参数.结果显示,不同的反应温度对应不同的饱和吸附量,当温度为298.15、313.15和328.15 K时,饱和吸附量分别为212.8、217.4和232.6 mg/g.分别用Langmuir方程和Freundlich方程对实验数据进行拟合,结果表明,此吸附过程更符合Langmuir等温吸附.在不考虑温度对吸附焓和吸附熵影响的前提下,计算得到吸附焓△H=21.28 kJ/mol,△S=89.18 J/K/mol以及△G<0.以上结果表明,CST对Cs的吸附过程是一个自发进行、既有物理吸附又有化学吸附的吸热反应.%Thermodynamical analysis of cesium adsorption on CST is considered to be one of the important approaches in studying the adsorption mechanism of cesium on CST. A series of parameters were obtained by measuring the change of the Cs+ ion concentration before and after the sorption. The CST sorption experiments were conducted with the CsNO3 solution at different concentrations and temperatures. The saturation adsorption was found to be 212.8, 217.4 and 232.6 mg/g at 298. 15, 313. 15 and 328. 15 K, respectively. The experimental data were fitted with the Langmuir model or the Freundlich model. The results showed that the Langmuir isotherm better fits this adsorption process. With the assumption that the adsorption enthalpy and adsorption entropy are independent of the temperature, theadsorption enthalpy and entropy were calculated to be 21. 28 kJ/mol and 89. 18 J ? K-1 ? Mol-1 , respectively, with a negative adsorption free energy. The results indicated that the adsorption of cesium on CST is a spontaneous and endothermic process, with both physical and chemical adsorptions involved.

  11. Synthesis and Crystal Structure of {N,N-bis[(1-methy-limidazol-2-yl)methyl]-β-alanine methylester]}dichlorocobalt(Ⅱ)%N,N-二(1-甲基咪唑基-1-亚甲叉)-β-丙氨酸甲酯二氯化钴(Ⅱ)配合物的合成与晶体结构

    Institute of Scientific and Technical Information of China (English)

    孙景佳; 陈佳民; 劳雁妮; 杨仕平

    2007-01-01

    一个新颖的N,N-二(1-甲基咪唑基-1-亚甲叉)-β-丙氨酸甲酯二氯化钴(Ⅱ)配合物被合成得到,并通过元素分析与X-射线单晶衍射手段对其结构进行了表征.晶体属于三斜晶系,P-1空间群,其中a=7.4540(9),b=10.2345(13),c=13.5999(17)(A),α=102.884(2),β=102.657(2),γ=107.548(2)v,V=917.4(2)(A)3,Mr=421.19,Z=2,Dc=1.525 g/cm3.单晶结构分析表明,钴(Ⅱ)被两个氯原子、两个咪唑环的氮原子与叔胺的氮原子所配位,构成一新颖的五配位的三角双锥配位环境,通过碳上的氢原子与氯原子和酯基的氧之间形成的非典型氢键使得分子构成三维的空间结构.%A new complex CoLCl2(L=N,N-bis[(1-methylimidazol-2-yl)methyl]alanine methylester)was synthesized and its crystal structure was determined by single-crystal x-ray diffraction.Crystal data:C14H21Cl2CoN5O2,triclinic,space group P-1 with a=7.4540(9),b=10.2345(13),c=13.5999(17)(A),α=102.884(2),β =102.657(2),γ=107.548(2)v,V=917.4(2)(A)3,Mr=421.19,Z=2,Dc=1.525 g/cm3,F(000)=434,μ=1.243 mm-1,the final R=0.0500 and wR=0.0712 for 2519 observed reflections(I 2(Ⅰ)).The Co (Ⅱ)atom wsa coordinated in trigonal bipyramid geometry by two chloride atoms,two imidazole nitogen atoms and a tertiary amine N atom.Structure analysis indicated that the structure was consolidated by some non-classical intermolecular and intramolecular weak hydrogen bonds which formed a three dimensional network in the solid.

  12. Selection and Adsorption Behavior of Resin for the Decaffeination of Tea%脱茶叶咖啡碱树脂的筛选及吸附行为的研究

    Institute of Scientific and Technical Information of China (English)

    王杰; 吴晖

    2012-01-01

    Taking the adsorption rate and adsorption capacity as indexes, the adsorption abilities of 10 kinds of resins were compared and the resin AL-1 was shown to be the best one with its caffeine-adsorption rate of 98.58%. Based on the thermodynamics and kinetics characteristics of the resin AL-1, the change of enthalpy was 21.84 kJ/mol, which indicated that the adsorption was exothermic physical absorption process. The value of free energy was positive and was reduced with the gradual increase of temperature. It indicated that the higher ambient temperature, the more easily caffeine was adsorbed. Equilibrium adsorption data was consistent with both Langmuir and Freundlich isotherms equation, which showed that it was single molecule layer adsorption. A Lagergren pseudo-first order rate equation was suitable to the adsorption process, which was mainly controlled by liquid film.%以茶汤中咖啡碱的吸附率及吸附量为指标,比较了静态吸附条件下10种树脂对茶叶咖啡碱的吸附效果,筛选出吸附效果最佳的树脂AL-1,并对AL-1的吸附热力学及动力学特性进行了研究.结果表明,AL-1对茶叶咖啡碱的吸附率高达98.58%,吸附晗变△H=21.84 kJ/mol,说明AL-1对咖啡碱的吸附是吸热的物理吸附过程,吸附自由能均为正值,且随吸附温度增加而减少,说明环境温度越高,吸附越容易.平衡吸附数据符合Langmuir和Freundlich等温吸附方程,说明吸附属单分子层吸附,吸附速率符合准一级动力学方程,吸附过程主要受液膜控制.

  13. Hydrothermal Petroleum in Active Continental Rift: Lake Chapala, Western Mexico, Initial Results.

    Science.gov (United States)

    Zarate-del Valle, P. F.; Simoneit, B. R.; Ramirez-Sanchez, H. U.

    2003-12-01

    Lake Chapala in western Mexico is located partially in the Citala Rift, which belongs to the well-known neotectonic Jalisco continental triple junction. The region is characterized by active volcanism (Ceboruco, Volcan de Fuego), tectonic (1995 earthquake, M=8, 40-50 mm to SW) and hydrothermal (San Juan Cosala & Villa Corona spas and La Calera sinter deposit) activities. Hydrothermal petroleum has been described in active continental rift (East African Rift) and marine spreading zones (Guaymas Basin, Gulf of California). In 1868 the Mexican local press reported that manifestations of bitumen were appearing in front of the Columba Cap on the mid south shore of Lake Chapala. This bitumen is linked to the lake bottom and when the water level decreases sufficiently it is possible to access these tar bodies as islands. Because of these manifestations the Mexican oil company (PEMEX) drilled an exploration well (2,348m) at Tizapan El Alto without success. Hydrothermal activity is evident in the tar island zone as three in-shore thermal springs (26.8 m depth, 48.5° C, pH 7.8 and oriented N-S). The preliminary analyses by GC-MS of the tar from these islands indicate hydrothermal petroleum derived from lake sedimentary organic matter, generated at low temperatures (150° -200° C). The tars contain no n-alkanes, no PAH or other aromatics, but a major UCM of branched and cyclic hydrocarbons and mature biomarkers derived from lacustrine biota. The biomarkers consist of mainly 17α (H),21β (H)-hopanes ranging from C27 to C34 (no C28), gammacerane, tricyclic terpanes (C20-C26), carotane and its cracking products, and drimanes (C14-C16). The biomarker composition indicates an organic matter source from bacteria and algae, typical of lacustrine ecosystems. 14C dating of samples from two tar islands yielded ages exceeding 40 kyrs, i.e., old carbon from hydrothermal/tectonic remobilization of bitumen from deeper horizons to the surface. The occurrence of hydrothermal petroleum in

  14. Electrochemical Properties of Organosilane Self Assembled Monolayers on Aluminum 2024

    Science.gov (United States)

    Hintze, Paul E.; Calle, Luz Marina

    2004-01-01

    Self assembled monolayers are commonly used to modify surfaces. Within the last 15 years, self assembled monolayers have been investigated as a way to protect from corrosion[1,2] or biofouling.[3] In this study, self assembled monolayers of decitriethoxysilane (C10H21Si(OC2H5)3) and octadecyltriethoxysilane (C18H37Si(OC2H5)3) were formed on aluminum 2024-T3. The modified surfaces and bare Al 2024 were characterized by dynamic water contact angle measurements, x-ray photoelectron spectroscopy (XIPS) and infrared spectroscopy. Electrochemical impedance spectroscopy (EIS) in 0.5 M NaCl was used to characterize the monolayers and evaluate their corrosion protection properties. The advancing water contact angle and infrared measurements show that the mono layers form a surface where the hydrocarbon chains are packed and oriented away from the surface, consistent with what is found in similar systems. The contact angle hysteresis measured in these systems is relatively large, perhaps indicating that the hydrocarbon chains are not as well packed as monolayers formed on other substrates. The results of the EIS measurements were modeled using a Randle's circuit modified by changing the capacitor to a constant phase element. The constant phase element values were found to characterize the monolayer. The capacitance of the monolayer modified surface starts lower than the bare Al 2024, but approaches values similar to the bare Al 2024 within 24 hours as the monolayer is degraded. The n values found for bare Al 2024 quickly approach the value of a true capacitor and are greater than 0.9 within hours after the start of exposure. For the monolayer modified structure, n can stay lower than 0.9 for a longer period of time. In fact, n for the monolayer modified surfaces is different from the bare surface even after the capacitance values have converged. This indicates that the deviation from ideal capacitance is the most sensitive indicator of the presence of the monolayer.

  15. Genotypic analyses of shiga toxin-producing Escherichia coli O157 and non-O157 recovered from feces of domestic animals on rural farms in Mexico.

    Science.gov (United States)

    Amézquita-López, Bianca A; Quiñones, Beatriz; Cooley, Michael B; León-Félix, Josefina; Castro-del Campo, Nohelia; Mandrell, Robert E; Jiménez, Maribel; Chaidez, Cristóbal

    2012-01-01

    Shiga toxin-producing Escherichia coli (STEC) are zoonotic enteric pathogens associated with human gastroenteritis worldwide. Cattle and small ruminants are important animal reservoirs of STEC. The present study investigated animal reservoirs for STEC in small rural farms in the Culiacan Valley, an important agricultural region located in Northwest Mexico. A total of 240 fecal samples from domestic animals were collected from five sampling sites in the Culiacan Valley and were subjected to an enrichment protocol followed by either direct plating or immunomagnetic separation before plating on selective media. Serotype O157:H7 isolates with the virulence genes stx2, eae, and ehxA were identified in 40% (26/65) of the recovered isolates from cattle, sheep and chicken feces. Pulse-field gel electrophoresis (PFGE) analysis grouped most O157:H7 isolates into two clusters with 98.6% homology. The use of multiple-locus variable-number tandem repeat analysis (MLVA) differentiated isolates that were indistinguishable by PFGE. Analysis of the allelic diversity of MLVA loci suggested that the O157:H7 isolates from this region were highly related. In contrast to O157:H7 isolates, a greater genotypic diversity was observed in the non-O157 isolates, resulting in 23 PFGE types and 14 MLVA types. The relevant non-O157 serotypes O8:H19, O75:H8, O111:H8 and O146:H21 represented 35.4% (23/65) of the recovered isolates. In particular, 18.5% (12/65) of all the isolates were serotype O75:H8, which was the most variable serotype by both PFGE and MLVA. The non-O157 isolates were predominantly recovered from sheep and were identified to harbor either one or two stx genes. Most non-O157 isolates were ehxA-positive (86.5%, 32/37) but only 10.8% (4/37) harbored eae. These findings indicate that zoonotic STEC with genotypes associated with human illness are present in animals on small farms within rural communities in the Culiacan Valley and emphasize the need for the development of control

  16. Lack of Male-Female Differences in Disposition and Esterase Hydrolysis of Ramipril to Ramiprilat in Healthy Volunteers after a Single Oral Dose

    Directory of Open Access Journals (Sweden)

    Tom B. Vree

    2003-01-01

    Full Text Available The objective of this study was to identify differences in disposition and esterase hydrolysis of ramipril between male and female volunteers. Plasma concentration and area under the concentration-time curve until the last measured concentration (AUCt data of ramipril and its active metabolite ramiprilat (-diacid were obtained from a randomised, cross-over bioequivalence study in 36 subjects (18 females and 18 males. Participants received a single 5-mg oral dose of two different formulations of ramipril (Formulation I and II. Plasma ramipril and ramiprilat concentrations were determined according to validated methods involving liquid chromatography-mass spectrometry. A total number of 2 � 34 available plasma concentration-time curves of both the parent drug and the metabolite could be analysed, and variations (50�100% coefficient of variation [CV] in plasma concentrations of both parent drug and metabolite were found. With both the formulations, the mean plasma concentrations-time curves of males and females were identical. The groups of female and male volunteers showed similar yields (AUCt = mg.h/L of the metabolite ramiprilat (p = 0.37; however, females showed a higher AUCt/kg than males (p = 0.046. This difference was solely attributed to the difference in body weight between males and females (p = 0.00049. In both male and female groups, a subject-dependent yield of active metabolite ramiprilat was demonstrated, which was independent of the formulation.There is a large variation in the ramiprilat t1/2β (50�60% CV. There is a group of subjects who showed a t1/2β of approximately 80 h (15% CV, and two apparent groups with a longer t1/2βfor each formulation (124 h, 22.5% CV; 166 h, 21.6% CV, respectively, p = 0.0013. This variation in the terminal half-life of ramiprilat is not sex related. In all three groups of half-lives, the corresponding Cmax values (mean � SD of ramiprilat in males and females were identical. Thus, with

  17. 紫杉醇脂质体联合顺铂、氟尿嘧啶一线治疗晚期胃癌的临床观察%A phase Ⅱ trial of paclitaxel liposome plus cisplatin and 5-fluorouracil as first line chemotherapy for advanced gastric cancer

    Institute of Scientific and Technical Information of China (English)

    鄢俊; 邱峰; 钟志宏; 张凌; 项晓军; 余锋; 熊建萍

    2009-01-01

    目的:评价紫杉醇脂质体联合顺铂、氟尿嘧啶(PCF方案)一线治疗晚期胃癌的临床疗效和毒副反应.方法:PCF方案一线治疗42例晚期胃癌的具体用法:紫杉醇脂质体175mg/m2 ,第1天静滴90min;顺铂75mg/m2,第1天静滴;亚叶酸钙400mg/m2,第1天滴注2h;氟尿嘧啶2.6g/m2,亚叶酸钙滴注结束后立即持续泵入46h.21天为1周期,每2周期按RESIST标准评价疗效,所有患者至少接受2周期化疗.结果:42例患者共接受192个周期的化疗,所有患者均可评价疗效.完全缓解3例(7.1%),部分缓解20例(47.6%),稳定12例(28.6%),进展7例,总有效率为54.8%,中位进展时间(TTP)6.5个月,中位生存时间(MST)13.9个月.常见的不良反应为血液学毒性,胃肠反应、肌肉酸痛、外周神经毒性较轻,以Ⅰ、Ⅱ级为主.10例(23.8%)发生Ⅲ~Ⅳ级粒细胞减少,伴发热1例(2.4%);Ⅲ级恶心呕吐反应4例(9.5%),Ⅲ级肌肉酸痛3例(7.1%),Ⅲ级外周神经毒性2例(4.7%),无化疗相关性死亡病例.结论:紫杉醇脂质体联合顺铂、氟尿嘧啶(PCF方案)一线治疗晚期胃癌疗效确切,不良反应轻,值得临床推广应用.

  18. A chalcone showing positional disorder, two related diarylcyclohexenones showing enantiomeric disorder and a related hydroxyterphenyl, all derived from simple carbonyl precursors.

    Science.gov (United States)

    Salian, Vinutha V; Narayana, Badiadka; Yathirajan, Hemmige S; Akkurt, Mehmet; Çelik, Ömer; Ersanlı, Cem Cüneyt; Glidewell, Christopher

    2015-07-01

    Four compounds are reported, all of which lie along a versatile reaction pathway which leads from simple carbonyl compounds to terphenyls. (2E)-1-(2,4-Dichlorophenyl)-3- [4-(prop-1-en-2-yl)phenyl]prop-2-en-1-one, C18H14Cl2O, (I), prepared from 4-(prop-1-en-2-yl)benzaldehyde and 2,4-dichloroacetophenone, exhibits disorder over two sets of atomic sites having occupancies of 0.664 (6) and 0.336 (6). The related chalcone (2E)-3-(4-chlorophenyl)-1-(4-fluorophenyl)prop-2-en-1-one reacts with acetone to produce (5RS)-3-(4-chlorophenyl)-5-[4-(propan-2-yl)phenyl]cyclohex-2-en-1-one, C21H21ClO, (II), which exhibits enantiomeric disorder with occupancies at the reference site of 0.662 (4) and 0.338 (4) for the (5R) and (5S) forms; the same chalcone reacts with methyl 3-oxobutanoate to give methyl (1RS,6SR)-4-(4-chlorophenyl)-6-[4-(propan-2-yl)phenyl]-2-oxocyclohex-3-ene-1-carboxylate, C23H23ClO3, (III), where the reference site contains both (1R,6S) and (1S,6R) forms with occupancies of 0.923 (3) and 0.077 (3), respectively. Oxidation, using 2,3-dichloro-5,6-dicyano-1,4-benzoquinone, of ethyl (1RS,6SR)-6-(4-bromophenyl)-4-(4-fluorophenyl)-2-oxocyclohex-3-ene-1-carboxylate, prepared in a similar manner to (II) and (III), produces ethyl 4''-bromo-4-fluoro-5'-hydroxy-1,1':3',1''-terphenyl-4'-carboxylate, C21H16BrFO3, (IV), which crystallizes with Z' = 2 in the space group P-1. There are no significant intermolecular interactions in the structures of compounds (I) and (II), but for the major disorder component of compound (III), the molecules are linked into sheets by a combination of C-H...O and C-H...π(arene) hydrogen bonds. The two independent molecules of compound (IV) form two different centrosymmetric dimers, one built from inversion-related pairs of C-H...O hydrogen bonds and the other from inversion-related pairs of C-H...π(arene) hydrogen bonds. Comparisons are made with related compounds.

  19. Steranes and triterpanes in the Beacon Supergroup samples from southern Victoria Land in Antarctica

    Science.gov (United States)

    Matsumoto, Genki I.; Machihara, Tsutomu; Suzuki, Noriyuki; Funaki, Minoru; Watanuki, Kunihiko

    1987-10-01

    Steranes and triterpanes in Beacon Supergroup samples (sedimentary rock and silicified wood) from Allan Hills and Carapace Nunatak of southern Victoria Land in Antarctica were studied to elucidate sources of organic materials, sedimentary paleoenvironment and thermal history after deposition. Relative abundances of C 27, C 28 and C 29 steranes and visual kerogen results of Beacon Supergroup samples from Allan Hills imply that organic materials in the sedimentary paleoenvironments are contributed mainly by vascular plants with some influence of microorganisms, while those of the Carapace Nunatak sample may be largely due to fern spores. The pristane/phytane and pristane/heptadecane ratios of the samples were generally close to unity and between 0.50 and 0.99, respectively, suggesting that the sedimentary paleoenvironment was shallow lacustrine with alternating oxic and anoxic conditions. The ( 22S/22R)-17α(H),21β(H)-C 31-C 33 triterpane ratios are approximately at thermal equilibrium values ( ca. 1.5) in most samples, while the ( 20S/20R)-5α(H), 14α(H), 17α(H)-C 29 sterane ratios and the (20R + 20S)-5α(H), 14β(H), 17β(H)/5α(H), 14α(H), 17α(H)-C 29 sterane ratios vary from 0.0 to 1.1 and from 0.0 to 1.4, respectively. Most of the ( 20S/20R)-5α(H), 14α(H), 17α(H)-C 29 sterane ratios did not reach thermal equilibrium values. The correlation coefficient between the ( 20S/20R)-5α(H), 14α(H), 17α(H)-C 29 sterane ratios and (20R + 20S)-5α(H), 14β(H), 17β(H)/5α(H), 14α(H), 17α(H)-C 29, sterane ratios is very high (0.96). These variable maturities probably reflect thermal effects of basaltic dikes on the Beacon Supergroup at Allan Hills and Carapace Nunatak during Jurassic time. Thermal stresses on the Beacon Supergroup prior to basaltic intrusion have been estimated to be quite low, so the paleotemperatures of this formation have been quite low.

  20. Gravity-driven membrane filtration as pretreatment for seawater reverse osmosis: linking biofouling layer morphology with flux stabilization.

    Science.gov (United States)

    Akhondi, Ebrahim; Wu, Bing; Sun, Shuyang; Marxer, Brigit; Lim, Weikang; Gu, Jun; Liu, Linbo; Burkhardt, Michael; McDougald, Diane; Pronk, Wouter; Fane, Anthony G

    2015-03-01

    In this study gravity-driven membrane (GDM) ultrafiltration is investigated for the pretreatment of seawater before reverse osmosis (RO). The impacts of temperature (21 ± 1 and 29 ± 1 °C) and hydrostatic pressure (40 and 100 mbar) on dynamic flux development and biofouling layer structure were studied. The data suggested pore constriction fouling was predominant at the early stage of filtration, during which the hydrostatic pressure and temperature had negligible effects on permeate flux. With extended filtration time, cake layer fouling played a major role, during which higher hydrostatic pressure and temperature improved permeate flux. The permeate flux stabilized in a range of 3.6 L/m(2) h (21 ± 1 °C, 40 mbar) to 7.3 L/m(2) h (29 ± 1 °C, 100 mbar) after slight fluctuations and remained constant for the duration of the experiments (almost 3 months). An increase in biofouling layer thickness and a variable biofouling layer structure were observed over time by optical coherence tomography and confocal laser scanning microscopy. The presence of eukaryotic organisms in the biofouling layer was observed by light microscopy and the microbial community structure of the biofouling layer was analyzed by sequences of 16S rRNA genes. The magnitude of permeate flux was associated with the combined effect of the biofouling layer thickness and structure. Changes in the biofouling layer structure were attributed to (1) the movement and predation behaviour of the eukaryotic organisms which increased the heterogeneous nature of the biofouling layer; (2) the bacterial debris generated by eukaryotic predation activity which reduced porosity; (3) significant shifts of the dominant bacterial species over time that may have influenced the biofouling layer structure. As expected, most of the particles and colloids in the feed seawater were removed by the GDM process, which led to a lower RO fouling potential. However, the dissolved organic carbon in the

  1. From farm to table: follow-up of Shiga toxin-producing Escherichia coli throughout the pork production chain in Argentina

    Directory of Open Access Journals (Sweden)

    Rocío eColello

    2016-02-01

    Full Text Available Pigs are important reservoirs of Shiga toxin-producing Escherichia coli (STEC. The entrance of these strains into the food chain implies a risk to consumers because of the severity of hemolytic uremic syndrome. This study reports the prevalence and characterization of Shiga toxin-producing Escherichia coli (STEC throughout the pork production chain. From 764 samples, 31 (4.05% were stx positive by PCR screening. At farms, 2.86% of samples were stx positive; at slaughter, 4.08% of carcasses were stx positive and at boning rooms, 6% of samples were stx positive. These percentages decreased in pork meat ready for sale at sales markets (4.59%. From positive samples, 50 isolates could be characterized. At farms 37.5% of the isolates carried stx1/stx2 genes, 37.5% possessed stx2e and 25%, carried only stx2. At slaughter we detected 50% of isolates positive for stx2, 33% for stx2e and 16% for stx1/stx2. At boning rooms 59% of the isolates carried stx1/stx2, 14% stx2e and 5% stx1/stx2/stx2e. At retail markets 66% of isolates were positive for stx2, 17% stx2e and 17% stx1/stx2. For the other virulence factors, ehxA and saa were not detected and eae gene was detected in 12% of the isolates. Concerning putative adhesins, agn43 was detected in 72%, ehaA in 26%, aida in 8% and iha in 6% of isolates. The strains were typed into 14 E. coli O groups (O1, O2, O8, O15, O20, O35, O69, O78, O91, O121, O138, O142, O157, O180 and ten H groups (H9, H10, H16, H21, H26, H29, H30, H32, H45, H46. This study reports the prevalence and characterization of STEC strains through the chain pork suggesting the vertical transmission. STEC contamination originates in the farms and is transferred from pigs to carcasses in the slaughter process and increase in meat pork at boning rooms and sales markets. These results highlight the need to implement an integrated STEC control system based on good management practices on the farm and critical control point systems in the food chain.

  2. Some empirical estimates of the H2 formation rate in photon-dominated regions

    Science.gov (United States)

    Habart, E.; Boulanger, F.; Verstraete, L.; Walmsley, C. M.; Pineau des Forêts, G.

    2004-02-01

    We combine recent ISO observations of the vibrational ground state lines of H2 towards Photon-Dominated Regions (PDRs) with observations of vibrationally excited states made with ground-based telescopes in order to constrain the formation rate of H2 on grain surfaces under the physiconditions in the layers responsible for H2 emission. We briefly review the data available for five nearby PDRs. We use steady state PDR models in order to examine the sensitivity of different H2 line ratios to the H2 formation rate R_f. We show that the ratio of the 0-0 S(3) to the 1-0 S(1) line increases with Rf but that one requires independent estimates of the radiation field incident upon the PDR and the density in order to infer Rf from the H2 line data. We confirm earlier work by \\cite{habart2003a} on the Oph W PDR which showed that an H2 formation rate higher than the standard value of 3 × 10-17 cm3 s-1 inferred from UV observations of diffuse clouds is needed to explain the observed H2 excitation. From comparison of the ISO and ground-based data, we find that moderately excited PDRs such as Oph W, S140 and IC 63 require an H2 formation rate of about five times the standard value whereas the data for PDRs with a higher incident radiation field such as NGC 2023 and the Orion Bar can be explained with the standard value of Rf. We compare also the H21-0 S(1) line intensities with the emission in PAH features and find a rough scaling of the ratio of these quantities with the ratio of local density to radiation field. This suggests but does not prove that formation of H2 on PAHs is important in PDRs. We also consider some empirical models of the H2 formation process with the aim of explaining these results. Here we consider both formation on classical grains of size roughly 0.1 μm and on very small (˜10 Å) grains by either direct recombination from the gas phase (Eley-Rideal mechanism) or recombination of physisorbed H atoms with atoms in a chemisorbed site. We conclude that

  3. Occurrence of Hybrid Escherichia coli Strains Carrying Shiga Toxin and Heat-Stable Toxin in Livestock of Bangladesh

    Science.gov (United States)

    Johura, Fatema-Tuz; Parveen, Rozina; Islam, Atiqul; Sadique, Abdus; Rahim, Md Niaz; Monira, Shirajum; Khan, Anisur R.; Ahsan, Sunjukta; Ohnishi, Makoto; Watanabe, Haruo; Chakraborty, Subhra; George, Christine M.; Cravioto, Alejandro; Navarro, Armando; Hasan, Badrul; Alam, Munirul

    2017-01-01

    Shiga toxin-producing Escherichia coli (STEC) and enterotoxigenic E. coli (ETEC) are important causes of diarrhea in humans and animals worldwide. Although ruminant animals are the main source of STEC, diarrhea due to this pathotype is very low in Bangladesh where ETEC remains the predominant group associated with childhood diarrhea. In the present study, E. coli strains (n = 35) isolated from Bangladesh livestock (goats, sheep, and cattle) and poultry (chicken and ducks) were analyzed for the presence of major virulence factors, such as Shiga toxins (STX-1 and STX-2), heat-labile toxin, and heat-stable toxins (STa and STb). Multiplex polymerase chain reaction results revealed 23 (66%) E. coli strains to be virulent possessing either sta (n = 5), stx (stx1, n = 8; stx2, n = 2), or both (n = 8) genes in varying combinations. Thirty-four percent (8/23) of strains from livestock were hybrid type that carried both stx (either stx1 or stx2) and ETEC-specific enterotoxin gene sta. Serotyping results revealed that the ETEC strains belonged to five serotypes, namely O36:H5, O174:H−, O152:H8, O109:H51, and O8:H21, while the STEC-producing strains belonged to serotypes O76:H19 (n = 3), O43:H2 (n = 2), O87:H16 (n = 2), OR:H2 (n = 1), O110:H16 (n = 1), and O152:H8 (n = 1). The STEC–ETEC hybrid strains belonged to serotypes O76:H19 (n = 3), O43:H2 (n = 2), O87:H16, OR:H2, and O152:H8. Forty percent (2/5) of the ETEC and 20% (2/10) of the STEC strains were multidrug resistant with the highest drug resistance (50%) being found in the hybrid strains. Molecular fingerprinting determined by pulsed-field gel electrophoresis and cluster analyses by dendrogram revealed that, genetically, STEC–ETEC hybrid strains were highly heterogeneous. Multidrug-resistant E. coli STEC–ETEC hybrid strains in domesticated animals pose a public health threat for humans in Bangladesh. PMID:28119905

  4. Spectral resolution of fluxional organometallics. The observation and FTIR characterization of all-terminal [Rh4(CO)12].

    Science.gov (United States)

    Allian, Ayman D; Garland, Marc

    2005-06-07

    In situ FTIR spectroscopy at 1 cm(-1) resolution was conducted on n-hexane solutions of the bridged [Rh4(CO)9(mu-CO)3] in the interval T= 268-288 K and P(T)= 0.1-7.0 MPa using either helium or carbon monoxide as dissolved gas. Analysis of the spectral data sets was conducted using band-target entropy minimization (BTEM), in order to recover the pure component spectra. A new spectral pattern was recovered with terminal vibrations at 2075, 2069.8, 2044.6 and 2042 cm(-1). The new spectrum is consistent with an all-terminal [Rh4(CO)12] species with a C(3v) anticubeoctahedron structure where 2 different [Rh(CO)3] moieties exist, although the presence of some Td structure can not be entirely excluded. The equilibrium between all-terminal [Rh4(CO)12] and the bridged [Rh(4)(CO)9(mu-CO)3] was determined in the presence of both helium and CO. The equilibrium constant K(eq)=[Rh4(CO)12]/[Rh4(CO)9(mu-CO)3] at 275 K was ca. 0.011 and the determined equilibrium parameters were Delta(r)G= 12.63 +/- 4.8 kJ mol(-1), Delta(r)H=-21.45 +/- 2.3 kJ mol(-1) and Delta(r)S=-114.3 +/- 8.35 J mol(-1) K(-1). The free energy indicates a very small difference between the bridged and terminal geometry, and the lower entropy is consistent with a higher symmetry. This finding helps to address a long-standing issue concerning the existence of various [M4(CO)12] symmetries. In a more general context, the present study illustrates the considerable utility of quantitative infrared spectroscopy (occurring on a fast vibrational timescale) combined with sophisticated deconvolution techniques in order to resolve systems which have been demonstrated to be fluxional on the NMR timescale.

  5. Structures and Spectroscopy Studies of Two M(II-Phosphonate Coordination Polymers Based on Alkaline Earth Metals (M = Ba, Mg

    Directory of Open Access Journals (Sweden)

    Kui-Rong Ma

    2013-01-01

    Full Text Available The two examples of alkaline-earth M(II-phosphonate coordination polymers, [Ba2(L(H2O9]·3H2O (1 and [Mg1.5(H2O9]·(L-H21.5·6H2O (2 (H4L = H2O3PCH2N(C4H8NCH2PO3H2, N,N′-piperazinebis(methylenephosphonic acid, (L-H2 = O3PH2CHN(C4H8NHCH2PO3 have been hydrothermally synthesized and characterized by elemental analysis, FT-IR, PXRD, TG-DSC, and single-crystal X-ray diffraction. Compound 1 possesses a 2D inorganic-organic alternate arrangement layer structure built from 1D inorganic chains through the piperazine bridge, in which the ligand L−4 shows two types of coordination modes reported rarely at the same time. In 1, both crystallographic distinct Ba(1 and Ba(2 ions adopt 8-coordination two caps and 9-coordination three caps triangular prism geometry structures, respectively. Compound 2 possesses a zero-dimensional mononuclear structure with two crystallographic distinct Mg(II ions. Free metal cations   [MgO6]n2+ and uncoordinated anions (L-H2n2- are joined together by static electric force. Results of photoluminescent measurement indicate three main emission bands centered at 300 nm, 378.5 nm, and 433 nm for 1 and 302 nm, 378 nm, and 434.5 nm for 2 (λex=235 nm, respectively. The high energy emissions could be derived from the intraligand π∗-n transition stations of H4L (310 nm and 382 nm, λex=235 nm, while the low energy emission (>400 nm of 1-2 may be due to the coordination effect with metal(II ions.

  6. The Study of Children Patients With Mycoplasma Pneumonia Infection With Clinical Testing Analysis%临床检验分析对小儿肺炎支原体感染的研究

    Institute of Scientific and Technical Information of China (English)

    赵文凤; 周文斌

    2015-01-01

    Objective Clinical testing methods for children patients with mycoplasma pneumonia infection are to be studied.MethodsReviewed and analyzed clinical testing results selected from 41 children patients with mycoplasma pneumonia infection who were treated in hospital from April 2013 to April 2015.Results There were 33 normal cases and 8 abnormal cases tested by urine routine examination respectively,11 cases of leucocytes count 10.0×109/L,7 cases of platelets count 20 mm/h,21 cases’ CRP >10 mg/L;11 cases of bacteria culture results were positive.Conclusion For treatment children patients with mycoplasma pneumonia infection,it is suggested to apply a comprehensive analysis to clinical testing,including urine routine test,blood routine test,vigor analysis,passive agglutination test and bacterial culture of sputum,etc,in order to improve diagnosis accuracy and prevent from misdiagnosis.%目的:深入研究小儿肺炎支原体感染的临床检验方法。方法选取于2013年4月~2015年4月期间在我院接受治疗的41例小儿肺炎支原体感染患儿的临床检验结果进行回顾性分析。结果尿常规检查正常的有33例,异常8例;11例白细胞计数<4.0×109/L,8例白细胞计数在(4.0~10.0)×109/L,22例白细胞计数>10.0×109/L;7例血小板<100×109/L,34例血小板≥100×109/L;表现为MP-IgM阳性的有27例;20例血沉>20 mm/h,21例CRP>10 mg/L;11例细菌培养结果显示为阳性。结论在对小儿肺炎支原体感染进行诊断时,要通过尿常规、血常规、血气分析、被动凝集试验、对痰液进行细菌培养等临床检验进行综合分析,提高确诊率,避免出现漏诊误诊的情况。

  7. Occurrence and characterization of Shiga toxin-producing Escherichia coli O157:H7 and other non-sorbitol-fermenting E. coli in cattle and humans in urban areas of Morogoro, Tanzania.

    Science.gov (United States)

    Lupindu, Athumani M; Olsen, John E; Ngowi, Helena A; Msoffe, Peter L M; Mtambo, Madundo M; Scheutz, Flemming; Dalsgaard, Anders

    2014-07-01

    Escherichia coli strains such as Shiga toxin-producing E. coli (STEC), enteropathogenic E. coli, enterotoxigenic, attaching, and effacing E. coli, and enteroinvasive E. coli cause diarrhea in humans. Although other serotypes exist, the most commonly reported STEC in outbreaks is O157:H7. A cross-sectional study was conducted to isolate and characterize non-sorbitol-fermenting (NSF) E. coli O157:H7 from urban and periurban livestock settings of Morogoro, Tanzania. Human stool, cattle feces, and soil and water samples were collected. Observations and questionnaire interview studies were used to gather information about cattle and manure management practices in the study area. E. coli were isolated on sorbitol MacConkey agar and characterized by conventional biochemical tests. Out of 1049 samples, 143 (13.7%) yielded NSF E. coli. Serological and antimicrobial tests and molecular typing were performed to NSF E. coli isolates. These procedures detected 10 (7%) pathogenic E. coli including STEC (n=7), enteropathogenic E. coli (EPEC) (n=2), and attaching and effacing E. coli (A/EEC) (n=1) strains. The STEC strains had the ability to produce VT1 and different VT2 toxin subtypes that caused cytopathic effects on Vero cells. The prevalence of STEC in cattle was 1.6%, out of which 0.9% was serotype O157:H7 and the overall prevalence of diarrheagenic E. coli in cattle was 2.2%. The serotypes O157:H7, O142:H34, O113:H21, O+:H-, O+:H16, and O25:H4 were identified. One ESBL-producing isolate showed the MLST type ST131. To our knowledge, this is the first finding in Tanzania of this recently emerged worldwide pandemic clonal group, causing widespread antimicrobial-resistant infections, and adds knowledge of the geographical distribution of ST131. Cattle manure was indiscriminately deposited within residential areas, and there was direct contact between humans and cattle feces during manure handling. Cattle and manure management practices expose humans, animals, and the environment

  8. Effective interactions between nanoparticles: Creating temperature-independent solvation environments for self-assembly

    Science.gov (United States)

    Yadav, Hari O. S.; Shrivastav, Gourav; Agarwal, Manish; Chakravarty, Charusita

    2016-06-01

    The extent to which solvent-mediated effective interactions between nanoparticles can be predicted based on structure and associated thermodynamic estimators for bulk solvents and for solvation of single and pairs of nanoparticles is studied here. As a test of the approach, we analyse the strategy for creating temperature-independent solvent environments using a series of homologous chain fluids as solvents, as suggested by an experimental paper [M. I. Bodnarchuk et al., J. Am. Chem. Soc. 132, 11967 (2010)]. Our conclusions are based on molecular dynamics simulations of Au140(SC10H21)62 nanoparticles in n-alkane solvents, specifically hexane, octane, decane and dodecane, using the TraPPE-UA potential to model the alkanes and alkylthiols. The 140-atom gold core of the nanocrystal is held rigid in a truncated octahedral geometry and the gold-thiolate interaction is modeled using a Morse potential. The experimental observation was that the structural and rheological properties of n-alkane solvents are constant over a temperature range determined by equivalent solvent vapour pressures. We show that this is a consequence of the fact that long chain alkane liquids behave to a good approximation as simple liquids formed by packing of monomeric methyl/methylene units. Over the corresponding temperature range (233-361 K), the solvation environment is approximately constant at the single and pair nanoparticle levels under good solvent conditions. However, quantitative variations of the order of 10%-20% do exist in various quantities, such as molar volume of solute at infinite dilution, entropy of solvation, and onset distance for soft repulsions. In the opposite limit of a poor solvent, represented by vacuum in this study, the effective interactions between nanoparticles are no longer temperature-independent with attractive interactions increasing by up to 50% on decreasing the temperature from 361 K to 290 K, accompanied by an increase in emergent anisotropy due to

  9. Extensive analysis of N-H...O hydrogen bonding in four classes of phosphorus compounds: a combined experimental and database study.

    Science.gov (United States)

    Hamzehee, Farahnaz; Pourayoubi, Mehrdad; Nečas, Marek; Choquesillo-Lazarte, Duane

    2017-03-01

    The N-H...O hydrogen bond is the characteristic interaction in the crystal structures of N-benzyl-P-phenyl-N'-(p-tolyl)phosphonic diamide, C20H21N2OP or (C6H5)P(O)(NHCH2C6H5)(NHC6H4-p-CH3), (I), diphenylphosphinic 1-methylpropylamide, C16H20NOP or (C6H5)2P(O)[NHCH(CH3)(C2H5)], (II), (S)-1-phenylethylammonium N-[(S)-1-phenylethyl]phenylphosphonamidate, C8H12N(+)·C14H15NO2P(-) or [S-(C6H5)CH(CH3)NH3][(C6H5)P(O){S-NHCH(CH3)(C6H5)}(O)], (III), and (4-methylbenzyl)ammonium diphenylphosphinate, C8H12N(+)·C12H10O2P(-) or [4-CH3-C6H4CH2NH3][(C6H5)2P(O)(O)], (IV). This article focuses on the N-H...O hydrogen bonds by considering the structures of (I), (II), (III) and (IV), and reviewing their analogous compounds, including 43 (C)P(O)(N)2, 102 (C)2P(O)(N), 31 (C)P(O)(N)(O) and 96 (C)2P(O)(O) structures, deposited in the Cambridge Structural Database (CSD). For the structures with a (C)P(O)(N)2 segment, only neutral hydrogen bonds were found in the CSD. The other three classes of compounds included both neutral and `charge-assisted' hydrogen bonds, and the (C)2P(O)(O) structures were particularly noticeable for a high number of cation-anion compounds. The overall tendencies of N...O distances in neutral and cation-anion compounds were compared. The N-H...O hydrogen-bond angles were also analyzed for the four classes of phosphorus compounds.

  10. Crystal structures of two substituted thia-zolidine derivatives.

    Science.gov (United States)

    Viswanathan, Vijayan; Rao, Naga Siva; Raghunathan, Raghavachary; Velmurugan, Devadasan

    2016-08-01

    In the first of the compounds reported herein, namely 6'-ferrocenyl-6a'-nitro-6',6a',6b',7',9',11a'-hexa-hydro-2H-spiro-[ace-naphthyl-ene-1,11'-chromeno[3',4':3,4]pyrrolo-[1,2-c]thia-zol]-2-one, [Fe(C5H5)(C29H21N2O4S)], (I), the thia-zolidine ring adopts a twist conformation on the methine N-C atoms. In the second compound, viz. 6'-(4-methoxy-phen-yl)-6a'-nitro-6',6a',6b',7',9',11a'-hexa-hydro-2H-spiro-[ace-naphthyl-ene-1,11'-chromeno[3',4':3,4]pyrrolo-[1,2-c]thia-zol]-2-one, [Fe(C5H5)(C26H19N2O5S)], (II), the thia-zolidine ring adopts an envelope conformation with a methine C atom as the flap. In both compounds, the pyrrolidine ring adopts a twist conformation on the thia-zolidine and tetra-hydro-pyran C atoms. The mean planes of the thia-zolidine and pyrrolidine rings subtend angles of 67.30 (1) and 62.95 (7)° in (I) and (II), respectively, while the mean plane of the pyrrolidine ring makes dihedral angles of 76.53 (1) and 87.74 (7)° with the ace-naphthyl-ene ring system in (I) and (II), respectively. In both compounds, an intra-molecular C-H⋯O hydrogen bond forms an S(7) ring motif. In the crystal of (I), mol-ecules are linked via two different C-H⋯O hydrogen bonds, forming chains along [001] and [100]. In (II), they are linked through C-H⋯O hydrogen bonds, forming dimers with an R 2 (2)(10) ring motif while C-H⋯π inter-actions link the mol-ecules in a head-to-tail fashion, forming chains along the a-axis direction.

  11. Crystal structures of two substituted thia­zolidine derivatives

    Science.gov (United States)

    Viswanathan, Vijayan; Rao, Naga Siva; Raghunathan, Raghavachary; Velmurugan, Devadasan

    2016-01-01

    In the first of the compounds reported herein, namely 6′-ferrocenyl-6a′-nitro-6′,6a′,6b′,7′,9′,11a′-hexa­hydro-2H-spiro­[ace­naphthyl­ene-1,11′-chromeno[3′,4′:3,4]pyrrolo­[1,2-c]thia­zol]-2-one, [Fe(C5H5)(C29H21N2O4S)], (I), the thia­zolidine ring adopts a twist conformation on the methine N—C atoms. In the second compound, viz. 6′-(4-methoxy­phen­yl)-6a′-nitro-6′,6a′,6b′,7′,9′,11a′-hexa­hydro-2H-spiro­[ace­naphthyl­ene-1,11′-chromeno[3′,4′:3,4]pyrrolo­[1,2-c]thia­zol]-2-one, [Fe(C5H5)(C26H19N2O5S)], (II), the thia­zolidine ring adopts an envelope conformation with a methine C atom as the flap. In both compounds, the pyrrolidine ring adopts a twist conformation on the thia­zolidine and tetra­hydro­pyran C atoms. The mean planes of the thia­zolidine and pyrrolidine rings subtend angles of 67.30 (1) and 62.95 (7)° in (I) and (II), respectively, while the mean plane of the pyrrolidine ring makes dihedral angles of 76.53 (1) and 87.74 (7)° with the ace­naphthyl­ene ring system in (I) and (II), respectively. In both compounds, an intra­molecular C—H⋯O hydrogen bond forms an S(7) ring motif. In the crystal of (I), mol­ecules are linked via two different C—H⋯O hydrogen bonds, forming chains along [001] and [100]. In (II), they are linked through C—H⋯O hydrogen bonds, forming dimers with an R 2 2(10) ring motif while C—H⋯π inter­actions link the mol­ecules in a head-to-tail fashion, forming chains along the a-axis direction. PMID:27536396

  12. Metabolism and antioxidant defense in the larval chironomid Tanytarsus minutipalpus: adjustments to diel variations in the extreme conditions of Lake Magadi

    Science.gov (United States)

    Wood, Chris M.; Bergman, Harold L.; Johannsson, Ora E.; Laurent, Pierre; Chevalier, Claudine; Kisipan, Mosiany L.; Kavembe, Geraldine D.; Papah, Michael B.; Brix, Kevin V.; De Boeck, Gudrun; Maina, John N.; Ojoo, Rodi O.; Bianchini, Adalto

    2017-01-01

    ABSTRACT Insect larvae are reported to be a major component of the simple but highly productive trophic web found in Lake Magadi (Kenya, Africa), which is considered to be one of the most extreme aquatic environments on Earth. Previous studies show that fish must display biochemical and physiological adjustments to thrive under the extreme conditions of the lake. However, information for invertebrates is lacking. In the present study, the occurrence of the larval chironomid Tanytarsus minutipalpus is reported in Lake Magadi for the first time. Additionally, changes in larval metabolism and antioxidant defense correlated with diel variations in the extremely hostile environmental conditions of the lake are described. Wide variations in water temperature (20.2-29.3°C) and dissolved oxygen content (3.2-18.6 mg O2 l−1) were observed at different times of day, without significant change in water pH (10.0±0.03). Temperature and dissolved oxygen were higher at 13:00 h (29.3±0.4°C and 18.6±1.0 mg O2 l−1) and 19:00 h (29.3±0.8°C and 16.2±1.6 mg O2 l−1) and lower at 01:00 h (21.1±0.1°C and 10.7±0.03 mg O2 l−1) and 07:00 h (20.2±0.4°C and 3.2±0.7 mg O2 l−1). Significant and parallel increases in parameters related to metabolism (cholinesterase, glucose, cholesterol, urea, creatinine and hemoglobin) and the antioxidant system (SOD, GPx, GR, GSH and GSSG) were observed in larvae collected at 13:00 h. In contrast, no significant changes were observed in pro-oxidants (ROS and NO), TOSC and oxidative damage parameters (LPO and DNA damage). Therefore, the observed increases in temperature and dissolved O2 content in Lake Magadi were associated with changes in the antioxidant system of T. minutipalpus larvae. Adjustments performed by the chironomid larvae were efficient in maintaining body homeostasis, as well as protecting biomolecules against oxidative damage, so that oxidative stress did not occur. GSH-GSSG and GPx-GR systems appeared to

  13. Metabolism and antioxidant defense in the larval chironomid Tanytarsus minutipalpus: adjustments to diel variations in the extreme conditions of Lake Magadi

    Directory of Open Access Journals (Sweden)

    Lucas F. Bianchini

    2017-01-01

    Full Text Available Insect larvae are reported to be a major component of the simple but highly productive trophic web found in Lake Magadi (Kenya, Africa, which is considered to be one of the most extreme aquatic environments on Earth. Previous studies show that fish must display biochemical and physiological adjustments to thrive under the extreme conditions of the lake. However, information for invertebrates is lacking. In the present study, the occurrence of the larval chironomid Tanytarsus minutipalpus is reported in Lake Magadi for the first time. Additionally, changes in larval metabolism and antioxidant defense correlated with diel variations in the extremely hostile environmental conditions of the lake are described. Wide variations in water temperature (20.2-29.3°C and dissolved oxygen content (3.2-18.6 mg O2 l−1 were observed at different times of day, without significant change in water pH (10.0±0.03. Temperature and dissolved oxygen were higher at 13:00 h (29.3±0.4°C and 18.6±1.0 mg O2 l−1 and 19:00 h (29.3±0.8°C and 16.2±1.6 mg O2 l−1 and lower at 01:00 h (21.1±0.1°C and 10.7±0.03 mg O2 l−1 and 07:00 h (20.2±0.4°C and 3.2±0.7 mg O2 l−1. Significant and parallel increases in parameters related to metabolism (cholinesterase, glucose, cholesterol, urea, creatinine and hemoglobin and the antioxidant system (SOD, GPx, GR, GSH and GSSG were observed in larvae collected at 13:00 h. In contrast, no significant changes were observed in pro-oxidants (ROS and NO, TOSC and oxidative damage parameters (LPO and DNA damage. Therefore, the observed increases in temperature and dissolved O2 content in Lake Magadi were associated with changes in the antioxidant system of T. minutipalpus larvae. Adjustments performed by the chironomid larvae were efficient in maintaining body homeostasis, as well as protecting biomolecules against oxidative damage, so that oxidative stress did not occur. GSH-GSSG and GPx-GR systems appeared to

  14. The Relationship Within Awareness of AIDS Prevention Among MSM, Social Internet and Preventive Service%男男性行为者艾滋病知识知晓与社会网络和预防服务的关系

    Institute of Scientific and Technical Information of China (English)

    王毅; 徐杰; 李志军; 张光贵; 李六林; 樊静

    2011-01-01

    目的 了解男男性行为者(MSM)艾滋病知识知晓现况,分析社会网络及艾滋病预防服务对知晓率的影响.方法 2009 ~ 06/09,采用应答者趋动招募抽样法(RDS),在MSM活动场所定时、定点进行艾滋病防治知识知晓、社会网络、预防服务等情况的招募和寻问式匿名现场调查.结果 共调查400人,艾滋病防治知识平均总知晓率为92.1%,获取知识主要途径互联网62.8%、朋友57.0%、电视44.2%、宣传材料35.3%.不同主要寻找性伴场所者艾滋病防治知识知晓率差异有统计学意义(H=21.254,P<0.01),以联网最高,其次为酒吧/歌舞厅/茶室/会所,以浴室/桑拿/按摩最低,其次是公园/公厕/草地;认识MSM朋友人数与知晓率相关性有统计学意义(rs=0.142,P<0.01),认识朋友多,知晓率相对较高;不同介绍参加调查关系知晓率差异有统计学意义(H=7.905,P<0.05),熟人介绍者最高,其次是好朋友,性伴介绍最低.近半年是否接受过HIV检测、知道检测结果、安全套发放、润湿剂发放、同伴教育、防艾宣传资料发放知晓率差异有统计学意义(Z=- 3.358、-2.308、-3.028、-3.106、- 3.531、-4.019,P<0.05),接受过相应预防性服务者知晓率相对较高;是否以互联网、朋友、宣传材料为主要艾滋病防治知识来源者知晓率差异有统计学意义(Z=-2.754、-3.08、-2.196,P<0.05),以此为主要来源者知晓率较高,为有效宣传来源途径.结论 绵阳市MSM艾滋病防治知识知晓率较高,但不平衡,受社会活动网络、接受艾滋病预防服务因素的影响,应针对性深入开展健康教育,提整体知晓率.%Objective To understand the current situation of AIDS prevention in MSM, analyze the influence by social Internet and AIDS prevention service. Methods During June to September in 2009, recruitment and fieldsurvey about the awareness of AIDS prevention, social Internet and prevention service were conducted

  15. Avaliação das alterações biomecânicas da córnea antes e após lasik em pacientes míopes e hipermetrópes utilizando Moriá® Sub-Bowman's Keratomileusis (SBK

    Directory of Open Access Journals (Sweden)

    Bruno de Freitas Valbon

    2012-10-01

    Full Text Available OBJETIVO: Avaliar e comparar as alterações biomecânicas da córnea por meio do Ocular Response Analyzer® (ORA Reichert Ophtalmics Instruments, Buffalo, New York, USA antes e após Lasik com Moriá ® Sub Bowman Keratomileusis (SBK One Use Plus (OUP em pacientes míopes e hipermetrópes. MÉTODOS: Foram estudados 33 olhos, sendo 19 olhos míopes e 14 olhos hipermetrópes submetidos à cirurgia refrativa com técnica Lasik com flap fino (100 µ utilizando Moriá SBK OUP. O ORA foi realizado no pré-operatório e 1 mês após a cirurgia para avaliar a biomecânica da córnea. O CH (Corneal Hysteresis, CRF (Corneal Resistance Factor, IOPg (goldmann gold standard, Goldmann correlated intraocular pressure a IOPcc (corneal compensated intraocular pressure e mais 38 variáveis biomecânicas da córnea derivadas do sinal de resposta foram avaliados. O Teste de Kolmogorov-Smirnov foi utilizado para avaliar a distribuição normal. O teste de Wilcoxon foi utilizado para comparar as variáveis antes e após a cirurgia para cada grupo. As diferenças entre as medidas pré e pós-operatórias dos olhos míopes foram comparadas com as diferenças obtidas nos olhos hipermetrópes, utilizando-se o teste de Mann-Whitney. Foi considerado como estatisticamente significante p < 0,05%. RESULTADOS: Houve diferença significativa antes e após Lasik em olhos míopes e hipermetrópes na variável IOPg(Wilcoxon, p <0,05, porém não houve em IOPcc. Somente em olhos míopes houve diferenças significativas em CH e CRF, antes e após Lasik com Moriá SBK OUP, como também 9 parâmetros derivados do ORA Waveform_Sinal Gráfico (aspect1, h1, dive1, path1, p1area1, W11, H11, and w2 path11; Wilcoxon, p <0,05. Em olhos hipermetrópes houve diferenças antes e após Lasik das seguintes variáveis: aspect2, h2, dive2, mslew2 e H21 (Wilcoxon p<0,05.Diferenças nas variáveis IOPg e p1area, antes e após Lasik foram maiores em olhos míopes do que hipermetrópes (Mann-Whitey, p

  16. Effects of Fermentation Temperature on Total Acidity and Dominant Microorganisms of Fermented Maize Mash%发酵温度对发酵玉米醪中总酸及主要微生物的影响

    Institute of Scientific and Technical Information of China (English)

    姜照; 杜金华; 孙文涛; 祝敏

    2011-01-01

    In order to provide basis for the production and quality improvement of the sour maize pancake,effects of fermentation temperatures(15,20,25,30,and 35℃) on population of lactic acid bacteria and yeasts,pH value,and total acidity of spontaneously fermented maize mash were investigated;The optimum fermentation time at different temperatures were determined by the total acidity of sour maize pancake.The result showed that with the prolonging of the time,the pH value decreased from 5.62 ~ 6.94 to 3.30 ~ 3.80,and the total acidity increased to 3.89 g/kg ~ 16.14 g/kg.It also showed that the optimum fermentation time were 72~84 h,72~108 h,48~72 h,21~27 h,24~27 h.The lactic acid bacteria and the yeasts co-interacted,and the population of the lactic acid bacteria had the same tendency at the five temperatures,that is,remaining stable and then decreasing slightly after reaching the maximum value.The population of the yeasts reached the maximum and gradually decreased at both 30℃ and 35℃.During fermentation,It is seen that the population of the lactic acid bacteria was obviously more than that of the yeasts.%测定了15、20、25、30、35℃五个温度下自然发酵玉米醪的pH值、总酸含量、乳酸菌及酵母菌数量的变化,研究比较了发酵温度对玉米醪中总酸含量及主要微生物数量的影响,并以玉米酸煎饼的总酸含量为参照,确定了不同温度下的最适发酵时间,以期为玉米酸煎饼的生产及质量的提高提供依据。结果表明,随着发酵时间的延长,pH值由5.62~6.94降低至3.30~3.80;总酸含量增加,初始范围为3.89~16.14 g/kg,最适的发酵时间分别是72~84 h、72~108 h、48~72 h、21~27 h、24~27 h;乳酸菌、酵母菌相互作用,乳酸菌数量5个温度下变化趋势大致相同,达到最大值后保持稳定并略有减少,酵母菌数量在温度较高时(30℃、35℃)达到最大值后逐渐减少,整个发酵过程中,乳酸菌的数量明显多于酵母菌的数量。

  17. A Literature Survey to Identify Potentially Volatile Iodine-Bearing Species Present in Off-Gas Streams

    Energy Technology Data Exchange (ETDEWEB)

    Bruffey, S. H. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Spencer, B. B. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Strachan, D. M. [Strata-G, Knoxville, TN (United States); Jubin, R. T. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Soelberg, N. R. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Riley, B. J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2015-06-30

    Four radionuclides have been identified as being sufficiently volatile in the reprocessing of nuclear fuel that their gaseous release needs to be controlled to meet regulatory requirements (Jubin et al. 2011, 2012). These radionuclides are 3H, 14C, 85Kr, and 129I. Of these, 129I has the longest half-life and potentially high biological impact. Accordingly, control of the release of 129I is most critical with respect to the regulations for the release of radioactive material in stack emissions. It is estimated that current EPA regulations (EPA 2010) would require any reprocessing plant in the United States to limit 129I release to less than 0.05 Ci/MTIHM for a typical fuel burnup of 55 gigawatt days per metric tonne (GWd/t) (Jubin 2011). The study of inorganic iodide in off-gas systems has been almost exclusively limited to I2 and the focus of organic iodide studies has been CH3I. In this document, we provide the results of an examination of publically available literature that is relevant to the presence and sources of both inorganic and organic iodine-bearing species in reprocessing plants. We especially focus on those that have the potential to be poorly sequestered with traditional capture methodologies. Based on the results of the literature survey and some limited thermodynamic modeling, the inorganic iodine species hypoiodous acid (HOI) and iodine monochloride (ICl) were identified as potentially low-sorbing iodine species that could present in off-gas systems. Organic species of interest included both short chain alkyl iodides such as methyl iodide (CH3I) and longer alkyl iodides up to iodododecane (C10H21I). It was found that fuel dissolution may provide conditions conducive to HOI formation and has been shown to result in volatile long-chain alkyl iodides, though these may not volatilize until later in the reprocessing sequence. Solvent extraction processes were found to be significant sources of various organic iodine-bearing species; formation of these

  18. EXPRESSION OF △Np63 AND MDM2 PROTEINS IN TRANSITIONAL CELL CARCINOMA OF URINARY BLADDER%膀胱移行细胞癌组织△Np63和MDM2蛋白表达及意义

    Institute of Scientific and Technical Information of China (English)

    张鲁伟; 周荣祥

    2007-01-01

    目的 探讨缺乏酸性N端反式激活区的截短型p63(△Np63)和MDM2蛋白在膀胱移行细胞癌(TCC)组织中的表达及其临床意义.方法 用免疫组织化学法,检测35例石蜡包埋TCC组织标本中△Np63和MDM2的表达,以38例正常膀胱黏膜作为对照.结果 膀胱癌组30例(83.3%)△Np63蛋白呈阳性表达,膀胱黏膜组7例(18.4%)呈阳性表达,两组比较差异有显著性(uc=5.75,P<0.01).膀胱癌组15例(42.9%)MDM2蛋白呈阳性表达,膀胱黏膜组3例(7.9%)呈阳性表达,两组差异有显著性(x2=11.99,P<0.01).在不同病理分级、临床分期TCC中,△Np63表达差异有显著性(H=21.09、14.99,P<0.01).随着TCC病理分级、临床分期升高,△Np63表达明显增强,呈显著正相关(r=0.64、0.51,P<0.01).在不同病理分级、临床分期TCC中,MDM2表达差异有显著性(x2=16.63,P<0.01;x2=6.72,P<0.05).30例△Np63蛋白阳性表达TCC组织中MDM2蛋白阳性表达10例(33.3%),两者呈显著相关性(x2=7.78,P<0.05).△Np63阳性表达主要集中在低分化、浸润性TCC中,而MDM2则主要表达在高分化、浅表TCC中.结论 △Np63和MDM2与膀胱肿瘤的发生发展密切相关,可作为膀胱肿瘤早期诊断和判断恶性程度的参考指标.

  19. Molecular distributions and carbon isotopic compositions of fatty acids in the surface sediments f rom Shenhu Area,northern South China Sea%神狐海域 Si te4 B表层沉积物中脂肪酸组成及其碳同位素分布特征

    Institute of Scientific and Technical Information of China (English)

    朱小畏; 茅晟懿; 吴能友; 孙永革; 管红香

    2013-01-01

    content of them ,the author believes that the surface sediments of the Shenhu area may be embraced by reducing environment . In addition ,eight isoprenoid acids detected in the samples ,mainly phytanic acid and 17β(H) ,21β(H)-32-hopanoic acid ,and a small amount of the pristane acid ,presumably for the joint contribution of chlorophyll A and bacterial microorganisms .

  20. 人类脂肪来源成体干细胞体外培养的生物学特征研究及供体年龄对其增殖的影响

    Institute of Scientific and Technical Information of China (English)

    雷磊; 廖威明; 盛璞义; 傅明; 何爱珊; 黄纲

    2007-01-01

    通过研究人类脂肪组织来源成体干细胞(human adipose tissue derived adult stem cells,hADAS细胞)体外培养的生物学特征及供体年龄对其生长增殖的影响,为其作为组织工程学研究和应用的种子细胞提供实验室研究基础.取不同年龄组志愿者(<20岁、21~40岁、41~60岁和>61岁),手术中切除少量皮下脂肪组织,酶消化法分离细胞,体外培养,传至20代.取培养第3代细胞,流式细胞仪检测细胞表面抗原标记物(CD29,CD34,CD44,CD45,CD49d,HLA-DR,CD106)和细胞周期.细胞培养传20代后进行细胞染色体组分析.MTT法分别检测各年龄组不同时间点吸光值,绘制生长曲线,根据公式TD=t1g2/1gNt-1gN0换算人类脂肪来源干细胞倍增时间(time doubling,TD).结果显示:酶消化法自皮下脂肪组织分离细胞,体外培养hADAS细胞,流式细胞仪检测示CD29+,CD34-,CD44+,CD45-,CD49d±,HLA-DR-,CD106-;G1期占90%(P10代);P20细胞染色体组分析显示为正常染色体,未见异常染色体,保持遗传稳定.绘制细胞生长曲线,<20年龄组TD为(11.22±0.73)h,21~40年龄组TD为(11.14±0.76)h,两组之间P>0.05,无显著性差异;41~60年龄组TD为(13.18±1.58)h,>61年龄组TD为(13.11±0.83)h,两组之间P>0.05,无显著性差异.<20年龄组TD与>61年龄组TD显著性差异,P<0.05.说明hADAS细胞可方便地取材于皮下脂肪组织,体外培养遗传特性稳定,生长活跃,青年组生长活性强于老年组,可以作为组织工程学种子细胞的新来源.

  1. Influence of Relief on Vegetation Factors and Agrotechnical Differentiation Measures in Transylvania Plain

    Science.gov (United States)

    Ioana Moraru, Paula; Rusu, Teodor; Bogdan, Ileana; Ioan Pop, Adrian

    2016-04-01

    Transylvanian Plain (TP), with an area of 395.616 hectares, has a special importance for Romanian agriculture being characterized as a region orographically represented by hilly areas hills whereas climatically appears as a plain. Physical-geographical conditions from TP (low level of forestation; climate specific to plains) have resulted in numerous land degradation phenomena: land erosion, landslide, draining of gradient springs and groundwater level. These conditions create a favourable framework for the development of anthropic morphogenetic processes, as well as those triggered by natural mechanisms, thus intensifying the pace and their territorial expansion. Rainfall, through annual distribution and spring-summer pluvial aggressiveness, require the implementation of preservation measures on arable land, particularly for spring cultures. Along with rainfall, more factors are involved: relief, by the high degree of fragmentation and through tilting slopes; vegetation, by the dominance of cultivated plants and by the advanced state of degradation of vegetal grasslands (especially on southern slopes); lithology, by the predominance of loose rocks (sand, marl, sandstone etc.). In order to determine the influence of landscape morphology on the agro-technical characterization of land, 11 HOBO Micro Stations (H21-002) have been implemented from April to October in the locality Caianu, at various altitudes (311-441 m) at exposure coverage (N, NW, W, S, SE, E, NE). HOBO Smart Temp (S-TMB-M002) temperature sensors and Decagon EC-5 (S-SMC-M005) moisture sensors were connected to HOBO Micro Stations. Additionally, in 4 of the 11 sites, tipping bucket rain gauges (RG3-M) were deployed to measure precipitation. Each station stored electronic data regarding ground temperature at 3 depths (10, 20, 30 cm), humidity at a depth of 10 cm, air temperature (1 m) and precipitation. Data were downloaded from the Micro Stations via a laptop computer using HOBOware Pro Software Version

  2. The solvent-extractable organic compounds in the Indonesia biomass burning aerosols - characterization studies

    Energy Technology Data Exchange (ETDEWEB)

    Fang, M.; Zheng, M.; Wang, F.; To, K.L. [The Hong Kong University of Science and Technology (Hong Kong). Applied Technology Center; Jaafar, A.B.; Tong, S.L. [Alam Sekitar Malaysia Sdn Bhd, Kuala Lumpur (Malaysia)

    1999-07-01

    } from C{sub 16} to C{sub 26} for n-alkanoic acid s and C{sub 18} < to C{sub 28} for n-alkanols, and the presence of abundant moretane (I7{beta}(H), 21{alpha}(H)-hopanes). The biomarkers dehydroabietic acid and retene were not found in the samples suggesting there is a difference in the long-distance transport samples of an Asian forest fire and the controlled experiments reported in the literature. Similar to the biomass burning in Amazonia (Abas et al., 1995), the present study also showed an absence of conifer tracers in the smoke aerosols indicating tropical wood sources. Abundant friedelin, a specific biomarker for smoke from oak wood fires (Standley and Simoneit, 1990), was present in the late September samples when the fire was more intense. (author)

  3. Effects of variations in flow characteristics through W.P. Franklin Lock and Dam on downstream water quality in the Caloosahatchee River Estuary and in McIntyre Creek in the J.N. “Ding” Darling National Wildlife Refuge, southern Florida, 2010–13

    Science.gov (United States)

    Booth, Amanda C.; Soderqvist, Lars E.; Knight, Travis M.

    2016-05-17

    Franklin Lock increases. The highest FDOM recorded during a survey was at Billy’s Creek. Chlorophyll fluorescence was positively correlated with flow at Franklin Lock, with 23 percent of the variation explained by the flow rate at Franklin Lock. An increase in flow rate at Franklin Lock resulted in a decrease in pH (21 percent of variation explained by flow rates). Data from the pH surveys indicate an increase in pH with distance from Franklin Lock. Turbidity and dissolved oxygen near the surface in McIntyre Creek were not correlated with flow rate at Franklin Lock. Moving-boat surveys did not document a change in turbidity or dissolved oxygen with a change in distance from the Franklin Lock. Correlations between Franklin Lock flow rate and water quality in McIntyre Creek indicate that releases at Franklin Lock affect water quality in the Caloosahatchee River Estuary and Ding Darling Refuge.

  4. Automation of Eastern Kentucky University Observatory and Preliminary Data

    Science.gov (United States)

    Ciocca, M.; Kilgore, E. E.; Williams, W. W.

    2012-06-01

    (Abstract only) Eastern Kentucky University is a regional comprehensive institution located in Richmond, Kentucky. Its service area includes much of the eastern part of Kentucky, commonly referred to as Appalachia. As such, Eastern has truly been a "school of opportunities" for the region. We offer three astronomy courses and one of them, AST 135, has an outdoor lab component, in which the students observe the moon and the brightest planets using 6-inch SCT. To expand our offerings by adding advanced classes in observational astronomy, and with support from the University and a small grant from the AAS (Small Research Grants), we constructed a small observatory for that purpose. We have a 14-inch telescope (C14 from Celestron), with a research grade mount (Paramount ME), housed permanently in a two-room facility. The telescope room has a retractable roof and the control room is insulated against the elements. The telescope is conveniently located near campus, in a location away from city lights and vehicular traffic, with access via a secure gate. The observatory is on a concrete pad poured directly onto the ground, to minimize vibrations. The instrument package consists of a SBIG STL-6303E CCD camera with filter wheel and full complement of photographic, narrow-band, and photometric filters (Ha and UBVRI). Courtesy of the AAS grant, we also have a temperature-compensated focuser (TCF-S3i), off-axis guider, and SBIG AO-L adaptive optics accessory. Our first step has been the measurement of our CCD transformation parameters, to assess the capabilities of our telescope-camera combination. We imaged a standard photometric field from Landolt (1992) (R.A. 09h 21m 32s, Dec. +02° 47' 00" (J2000, Plate 38 of Landolt). Data were obtained with a time integration of 90 seconds, binned 2 x 2 (~1 arcsec/pixel) at air mass X = 1.31. We determined the CCD transformation parameter as described by the AAVSO document "Computing and Using CCD transformation coefficients" (Cohen 2003

  5. p53凋亡刺激蛋白2对饥饿诱导的大肠癌HCT116 p53-/-细胞自噬和凋亡的影响%The role of ASPP2 in starvation-induced autophagy and apoptosis of HCT116 cell line

    Institute of Scientific and Technical Information of China (English)

    侯庆生; 丁谓; 陈德喜; 张玉林; 郭洪亮

    2013-01-01

    目的 探讨p53凋亡刺激蛋白2(apoptosis stimulating protein 2 0f p53,ASPP2)对饥饿诱导的大肠癌HCT116 p53-/-(p53缺失)细胞自噬和凋亡的影响.方法 实验分3组:(1)绿色荧光蛋白腺病毒(green fluorescent protein adenovirus,rAd-GFP)感染组(对照组);(2)自噬抑制剂LY294002处理组;(3) ASPP 2腺病毒(ASPP2 adenovirus,rAd-ASPP2)感染组.无血清培养基分别培养0、24、48 h诱导细胞自噬和凋亡.利用calcein/PI吸收试验观察各组细胞凋亡水平.细胞转染红色荧光蛋白自噬质粒Lc3(cerise fluorescent protein autophagy plasmid Lc3,CFP-Lc3),在荧光显微镜下观察各组细胞自噬水平.结果 rAd-GFP感染组饥饿24h细胞的自噬水平升高显著(0 h:1.04±0.24;24 h:12.17 ±0.86,P<0.05),而凋亡水平改变差异无统计学意义(0 h:2.01%±0.06%;24 h:3.23%±0.34%,P>0.05);饥饿时间延长至48 h,自噬水平(0 h:1.04±0.24;48 h:21.09±3.32)和凋亡水平(0h:2.01%±0.06%;48 h:30.20%±3.18%)升高,差异均具有统计学意义(均P<0.05).使用LY294002抑制细胞自噬,饥饿24 h细胞凋亡显著增多(rAd-GFP组:3.23%±0.34%;LY294002组:15.68%±1.24%,P<0.01),而饥饿48 h凋亡显著减少(rAd-GFP组:30.20%±3.18%;LY294002组:25.44%±3.01%,P <0.05).rAd-ASPP2感染组饥饿24 h自噬显著降低(rAd-GFP组:12.17±0.86;ASPP2组:1.45±0.45,P<0.01),而凋亡显著升高(rAd-GFP组:3.23%±0.34%;ASPP2组:10.45% ±0.81%,P<0.05);饥饿48 h自噬(rAd-GFP组:21.09 ±3.32;ASPP2组:29.93±3.48)和凋亡(rAd-GFP组:30.20%±3.18%;ASPP2组:36.72%±2.74%)水平均显著升高(均P<0.05).结论 ASPP2通过对自噬的双向调节促进饥饿诱导的大肠癌HCT116 p53-/-细胞凋亡.%Objective To investigate the role of ASPP2 (apoptosis stimulating protein 2 of p53,ASPP2) in starvation-induced autophagy and apoptosis of colorectal cancer HCT116 p53-/-(p53 gene deletion) cell line.Methods The study included three

  6. 犬咬伤创口感染分布及特点的研究%Distribution and characteristics of infection in dog bite wounds

    Institute of Scientific and Technical Information of China (English)

    陈瑞丰; 王立秋; 黄立嵩; 王雪飞

    2011-01-01

    Objective To study the distribution and characteristics of infection in dog bite wounds in different parts of body.Methods Six groups of 150 dog bite patients with the wounds at their head, face and neck, hand, foot, upper limb (to the exclusion of the hand), and lower limb (to the exclusion of the foot), and trunk respectively, totally 900, underwent observation of the infection rate,infection time, clinical manifestations, and complications.Results The infection rate of the hand group was 26.0%,not significantly different from that of the foot group (22.0%, P>0.05), however,both were significantly higher than those of the head, face, and neck, upper limb (to the exclusion of the hand), lower limb (to the exclusion of the foot), and trunk groups (7.3%, 10.0%, 9.3%, and 11.3% respectively, all P<0.05).The infection time of the hand group was (13.7±6.7)h, not significantly different from that of the foot group [(16.0±7.6)h, P>0.05], however, both were significantly shorter than those of the head, face and neck, upper limb (to the exclusion of the hand), lower limb (to the exclusion of the foot), and trunk groups [(23.3±11.4)h, (23.1±8.4)h, (21.9±7.8)h, and (20.1±6.8)h respectively, all P<0.05].And there were not significant differences in the infection rate and infection time among the 4 groups except the hand and foot groups (all P>0.05).The main clinical manifestations of the dog bite wound infection included local redness, edema, purulent drainage, and fever.The main complications included abscess, lymphangitis/erysipelas, arthritis, and tenosynovitis.Conclusion Hand and foot wounds are the sites most liable to suffer from infection and severe complications among all the dog bite wounds.%目的 探讨各部位犬咬伤创口的感染及临床特点.方法 900例65岁以下的犬咬伤致撕裂伤患者,按伤部分为头面颈组、手部组、足部组、上肢组、下肢组和躯干组,分别观察各组的感染率、感染时间

  7. EV71-2A突变质粒的构建及体内外功能初探%Construction of pcDNA3 . 1-EV71-2A mutant and preliminary studying related biological functions

    Institute of Scientific and Technical Information of China (English)

    原素梅; 徐超; 张煦; 王源; 谢冰玉; 熊庆; 彭宜红

    2016-01-01

    Objective To construct EV71-2Amut(pcDNA3. 1-EV71-2A mutant plasmid)and studying its functions in vitro and in vivo, so as to provide an experiemental base for the further studying the active site and biological function of 2A pro-teinase. Methods By using of site-directed mutagenesis system based on PCR, EV71-2Amut was constructed on site-directed mutagenesis of 21His,39Asp and 110Cys genes and confirmed by sequencing analysis. Then EV71-2Amut and pRL-CMV(Cyto-megalovirus, CMV) were co-transfected to human rhabdomyosarcoma cell( RD cell) , and the enzyme activity inside cells was determined and compared with effect to pRL expression level between wild type EV71-2Apro and EV71-2Amut . EV71-2A mR-NA was detected by RT-PCR, and its effect on the quadriceps femoris of BALB/c mice was observed on histopathological changes, which reflected its transcription level and activity in vivo. Results The constructed EV71-2Amut sequence was i-dentical with we expected,the RL activity detected at cellular level from EV71-2Amut groups were significantly higher than that of EV71-2Apro groups (P<0. 05). EV71-2A-mRNA were detected by RT-PCR in quadriceps femoris from the mice injected with EV71-2Apro and EV71-2Amut . Compared with the control group injected with wild type 2A,inflammatory cell infiltration and coagulation necrosis were mild in quadriceps femoris injected with EV71-2Amut . Conclusion EV71-2Amut with H21N+D39E+C110A was successfully constructed. and its protease activity was almost abolished in RD cell and BABL/c mice. This work provides a ground work for the further studying the biological functions of EV71-2A protease.%目的:构建pcDNA3.1-EV71-2A的突变质粒(EV71-2Amut),并对其功能进行检测,为进一步研究肠道病毒71型(Enterovirus type 71,EV71)2A蛋白酶的活性位点及其生物学功能奠定实验基础。方法利用聚合酶链式反应(PCR)定点诱变技术,定点突变编码EV71-2A第21His、39Asp 和110Cys 氨基酸的位点,构建EV71

  8. Evaluation of computer-assisted ThinPrep imaging system in the screening of cervical cancer and precancerous lesion%TIS在宫颈癌和癌前病变筛查中的价值评价

    Institute of Scientific and Technical Information of China (English)

    米贤军; 王莹; 沈铿; 吴秋良; 肖琳; 陈昂; 徐秀梅; 孪峰; 钟守军

    2013-01-01

    目的 评价新柏氏电脑辅助阅片系统(TIS)对宫颈癌及癌前病变的诊断价值.方法 收集2011年6月至2012年6月参加中山市大规模免费宫颈癌筛查中妇女的资料,选择做过TIS检测并追踪到有确切组织病理学诊断结果的600例病例为研究对象,将ASCUS/AGC+病变列为细胞学阳性病例,将CIN1+病变列为病理学阳性病例,以病理学检查为金标准,评价TIS检测的诊断价值.结果 600例妇女中,TIS检测结果为癌(CA)9例,高度鳞状上皮内病变(HSIL) 66例,低度鳞状上皮内病变(LSIL) 104例,不除外高度鳞状上皮内病变的不典型鳞状细胞(ASC-H) 21例,非典型鳞状细胞/非典型腺细胞(ASCUS/AGC) 30例,正常(WNL) 370例.以病理学诊断结果为金标准,TIS检测的灵敏度为93.95%,特异度为92.73%,约登指数为0.867,阳性似然比12.92,阴性似然比0.065,Kappa值0.854,总符合率为93.17%,阳性预测值87.83%,阴性预测值96.49%.TIS与病理学结果的符合率在CA、HSIL、LSIL中分别为100%、90.91%和72.12%,TIS对CA和HSIL的符合率高于LSIL (P<0.01).结论 TIS对宫颈癌及癌前病变有较高的诊断价值,特别是对CA和HSIL.它是一种高效、高质量和高准确率的宫颈癌及癌前病变筛查技术.%Objective To study the diagnostic value of computer-assisted ThinPrep imaging system(TIS) in the screening of cervical cancer and precancerous lesion.Methods The clinical data of 600 cases who participated voluntarily in the screening of large-scale cervical cancer for free in Zhongshan were collected from June 2011 to June 2012.ASCUS/AGC and above were postive cytology and the postive results of pathological examination were CIN and above.Histopathological results were used as gold standard to calculate the diagnostic value of TIS technique.Results A total of 600 cases were detected by TIS,and the testing results showed 9 cases of CA,66 cases of HSIL,104 cases of LSIL,21 cases of ASC-H,30 cases of ASCUS

  9. The fluid management for mild and moderate hyponatremia after acute cervical spinal cord iniurv%急性颈脊髓损伤后轻中度低钠血症的液体管理

    Institute of Scientific and Technical Information of China (English)

    张仲汇; 韩岳; 颜柳子

    2011-01-01

    group A and B, there were no statistics meaning about serum sodium, MAP, CVP, urine volume of 24 h,urine sodium of 24 h,urine osmoticpressure/sodium osmoticpressure after 24 h different treatments. At 72 h after treatments, serum sodium[(128.98±4.32)mmol/L] ,MAP[(64.32±3.25)mmHg],CVP[(5.14±0.68)cmH2O] in group A were lower than those in group B(P<0.05). Urine volume of 24 h[(2 100.32±32.21)mL],urine sodium of 24 h [(189.25±H.21) mmol/L],urine osmoticpressure/sodium osmoticpressure(2.78±0.79)in group A were higher than those in group B (P<0.01). Conclusion: The mild and moderate hyponatremia and interrelated complications after ACSCI can be retrieved earlier by liberal fluid management than conservative fluid management.

  10. Characterization of seed oils from different varieties of watermelon [Citrullus lanatus (Thunb.] from Pakistan

    Directory of Open Access Journals (Sweden)

    Mahmood, Z.

    2012-10-01

    Full Text Available This paper reports the physicochemical characteristics of the seed oils from different varieties of watermelon (Citrullus lanatus cultivated in Pakistan, namely Sugar Baby, Q-F-12, D-W-H-21 and Red Circle-1885. The oil and crude protein contents from watermelon seeds, within the range of 28.25 to 35.65% and 20.50 to 35.00%, respectively, varied significantly (p -1 of oil, saponification index (190.20-205.57 mg KOH g-1 of oil, unsaponifiable matter (0.54-0.82% and color (1.12-4.30 R + 12.20-33.40 Y. The oils revealed a reasonable oxidative parameter range as depicted by the determinations of specific extinction at 232 and 270 nm (2.90-4.40 and 2.05- 3.09, respectively, p-anisidine value (5.60-7.70 and peroxide value (2.90-5.06 meqO2 kg-1 of oil. Linoleic acid was the major fatty acid found in all the seed oils with contributions of 45.30-51.80% of the total fatty acids (FA. Other fatty acids detected were known to be oleic acid (20.2- 23.5%, palmitic acid (15.1-16.9% and stearic acid (11.5- 14.4%. The contents of α- and δ-tocopherol in the oils accounted for 120.6-195.6 and 9.1-58.3 mg kg-1, respectively. The physicochemical attributes of the watermelon seed oils showed a wider variation among the varieties tested. The results of the present study indicate that the seeds of the tested watermelon varieties from Pakistan are a potential source of high-linoleic oil and thus can be explored for commercial use and value addition.Se presentan las características físico-químicas de aceites de diferentes variedades de semillas de sandías (Citrullus lanatus cultivadas en Pakistán: Sugar Baby, QF-12, DWH-21 y Círculo rojo-1885. El aceite y el contenido de proteína cruda de las semillas de sandía están dentro de los rangos: 28,25-35,65% y 20,50-35,00%, respectivamente y varian significativamente (p -1 de aceite, índice de saponificación (190,20-205,57 mg de KOH g-1 de aceite, insaponificable (0,54-0.82% y color (1.12-4.30 de I + 12.20- 33.40 y

  11. Global system for hydrological monitoring and forecasting in real time at high resolution

    Science.gov (United States)

    Ortiz, Enrique; De Michele, Carlo; Todini, Ezio; Cifres, Enrique

    2016-04-01

    connection) and not need update (all upgrade are deployed on the remote server)and DSS is a classical client-server application. The client side will be an HTML 5-CSS 3 application, it runs in one of the most common browser. The server side consist in: A web server (Apache web server); a map server (Geoserver); a Geographical q3456Relational Database Management Sytem (Postgresql+Postgis); Tools based on GDAL Lybraries. A customized web page will be implemented to publish all hydrometeorological information and forecast runs (free) for all users in the world. In this first presentation of the project are invited to attend all those scientific / technical people, Universities, Research Centers (public or private) who want to collaborate in it, opening a brainstorming to improve the System. References: • Liu Z. and Todini E., (2002). Towards a comprehensive physically based rainfall-runoff model. Hydrology and Earth System Sciences (HESS), 6(5):859-881, 2002. • Thielen, J., Bartholmes, J., Ramos, M.-H., and de Roo, A., (2009): The European Flood Alert System - Part 1: Concept and development, Hydrol. Earth Syst. Sci., 13, 125-140, 2009. • Coccia C., Mazzetti C., Ortiz E., Todini E., (2010) - A different soil conceptualization for the TOPKAPI model application within the DMIP 2. American Geophysical Union. Fall Meeting, San Francisco H21H-07, 2010. • Pappenberger, F., Cloke, H. L., Balsamo, G., Ngo-Duc, T., and Oki,T., (2010) Global runoff routing with the hydrological component of the ECMWF NWP system, Int. J. Climatol., 30, 2155-2174, 2010. • Coccia, G. and Todini, E., (2011). Recent developments in predictive uncertainty assessment based on the Model Conditional Processor approach. Hydrology and Earth System Sciences, 15, 3253-3274, 2011. • Wu, H., Adler, R. F., Hong, Y., Tian, Y., and Policelli, F.,(2012): Evaluation of Global Flood Detection Using Satellite-Based Rainfall and a Hydrologic Model, J. Hydrometeorol., 13, 1268-1284, 2012. • Simth M. et al., (2013

  12. Effect Evaluation of Dexmedetomidine and Midazolam in Infants in Mechanical Ventilation%婴幼儿机械通气时使用右旋美托咪定和咪达唑仑的效果评价

    Institute of Scientific and Technical Information of China (English)

    郑敏; 田刚; 李虎年; 刘勇; 王群

    2012-01-01

    Objective: To compare infants sedation effect and difference when using dexmedetomidine and midazolam in mechanical ventilation. Methods: To collect 1CU patients requiring mechanical ventilation from February 2009 to October 2011 in our hospital, they received intravenously midazolam 0.05 mg·kg-1·h-1 dexmedetomidine 0.25 or 0.5 μg·kg-1·h-1 respectively. At the same time, they were given interruptably morphine according to pathogenetic condition.We evaluate sedative effect using Ramsay sedation scale and BIS. Results: Sixty patients were randomly assigned into three groups (n=20 for each group). Continuing infusion time in midazolam group (group M), D1 group and D2 groups were 22±8h, 21 ± 10h and 22±9h respectively. Average infusion rate in M, D1 and D2 groups were 0.22±0.05 mg ·kg-1·h-1h, 0.28±0.07 μg·kg-1·h-1 and 0.21 ±0.05 μg·kg-1·h-1respectively. There was no significant difference among groups. The morphine dose in M, D1 and D2 groups were 36 mg·kg-1· 24h-1, 29 mgμg·kg-1· 24h-1 and 20 mg·kg-1·24h-1 respectively. Compared with Group M, the morphine dose in Group Dl decreased, but there was no significant difference (P>0.05). However the morphine dose in Group D2 obviously decreased, there was significant difference compared with Group M (P<0.05). Ramsay sedation scale and BiS value have no significant difference in three groups. Conclusion: Dexmedetomidine used in infant is safe and effective, 0.5 μg·kg-1·h-1 dose of dexmedetomidine bring about effective sedation and decreased morphine dose in 24h significantly.%目的:比较婴幼儿在机械通气镇静时使用右旋美托咪定和咪达唑仑效果.方法:收集我院2009年2月至2011年10月入住ICU需要机械通气且镇静时间大于24h的患儿60例,随机分为3组,每组20例,右旋美托咪啶1组(输注剂量为0.25 μg· kg-l·h-1,D1组)、2组(输注剂量为0.5 μg- kgq·h-1,D2组)维持镇静,咪达唑仑组(输注剂量为0.05 mg·kg1·h-1,M组)维持镇静.同

  13. Application of sodium citrate combined with modified dialysate in continuous venous-venous hemodialysis%枸橼酸钠抗凝联合透析液配方改良在连续性静脉-静脉血液透析中的应用

    Institute of Scientific and Technical Information of China (English)

    兰洋; 齐华林; 庄守纲; 严海东

    2012-01-01

    析液流量、血流量、4%枸橼酸钠和氯化钙流量.记录患者动脉血气、外周血及透析器后游离钙离子浓度、血浆总钙浓度、管路和滤器的凝血情况和使用时间,观察治疗中的不良反应.结果 在血液透析过程中两组患者生命体征平稳,无1例患者发生抽搐、痉挛等明显低钙血症的表现.RCA组的滤器使用时间为(74±42)h,显著长于肝素组的(32士26)h(P<0.01).22例(56.4%)患者发生代谢性碱中毒,通过增加透析液流量250~500 mL/h,21例(95.5%)患者在48 h内达到酸碱平衡.结论 枸橼酸钠抗凝联合血液透析液处方改良应用在AKI合并活动性或高危出血患者行CVVHD时,既不加重患者出血倾向,又能够达到临床治疗效果.

  14. 6246例急诊住院危重患者抢救室滞留的Cox回归分析%Cox regression analysis of 6246 critically ill patients with prolonged stay in emergency room

    Institute of Scientific and Technical Information of China (English)

    叶立刚; 张茂; 何小军; 周光居; 沈伟锋; 干建新

    2011-01-01

    滞留的危险因素.结果 (1)全年经急诊抢救室住院的危重患者6246例,抢救室滞留的时间(中位数、四分位间距)为11 h(3~23 h),有56.6%的患者滞留时间超过6h,21.6%的患者滞留时间超过24h.(2)单因素分析显示影响患者滞留的最重要因素是专科病房的床位状况,其次为患者的医疗费用支持状况、病情是否涉及个多科室、是否急诊手术、收住病房的类型、主诊科室、年龄、性别和就诊时间段.(3)Cox多因素回归分析提示,最主要的影响因素为专科病房的床位状况、患者的医疗费用支持状况和病情是否涉及多科室;其次为是否急诊手术、收住病房的类型、主诊科室、性别和就诊时间段,年龄不影响患者的滞留时间.结论 该家医院经急诊收住院的危重患者在抢救室滞留时间偏长,主要的影响因素是专科病房不能及时提供床位,病情涉及多科室而偏复杂,患者的医疗费用支付困难,值得进一步的研究.

  15. Characteristics of cortical mapping in response to acid exposure in non-erosive reflux disease and erosive esophagitis using functional magnetic resonance imaging%应用fMRI研究非糜烂性反流病和糜烂性食管炎患者酸灌注时脑激活模式的差异

    Institute of Scientific and Technical Information of China (English)

    杨敏; 李兆申; 陈东风; 徐晓蓉; 许国铭; 邹多武; 房殿春

    2008-01-01

    目的 探索食管内脏高敏感性形成的脑机制.方法 2005年9月至2007年6月随机选择31例非糜烂性反流病(NERD)患者、13例糜烂性食管炎(EE)患者和12名正常对照者参与实验,并将NERD患者分为感知过敏组(NERD-H)21例和感知正常组(NERD-N)10例.利用血氧水平依赖脑功能磁共振成像(BOLD-fMRI)技术对比研究食管酸灌注时NERD-H组、NERD-N组、EE患者及正常对照者大脑功能活动区域定位、MR-BOLD信号激活及消退模式的差异.结果 NERD-H组酸灌注时激活的脑区包括单侧或双侧第二躯体感觉皮质(S Ⅱ)、初级躯体感觉皮质(S Ⅰ)、前额叶皮质(右侧为主)、框额皮质、岛叶皮质、楔前叶、杏仁体、腹侧纹状体、运动区/辅助运动区及小脑半球,且以双侧大脑激活为主.NERD-H组上述感兴趣区(ROI)区的fMRI峰值影像强度和最大磁共振(MR)信号增加幅度明显高于NERD-N组和正常对照组(均P<0.01),前扣带回激活信号值(562±104)明显低于正常组(587±126,P<0.05),但显著高于EE组(535±91,P<0.05).酸灌注刺激后,NERD-H组初始影像潜伏期、峰值影像潜伏期(1.7 min±0.9 min、4.5 min±1.3 min)均明显短于NERD-N组(4.0 min±1.1 min、6.8 min±1.6 min,均P<0.01)和正常对照组(5.4 min±1.7 min、7.2 min±1.5 min,均P<0.01).NERD-H组双侧SⅡ、右前额皮质信号消退失活幅度(26.5%±5.4%、20.3%±3.0%)均明显高于NERD-N组(8.2%±2.2%、16.4%±3.6%,均P<0.05)和EE组(11.9%±4.8%、11.7%±3.1%,均P<0.01),而正常对照组前扣带回的MR信号消退失活幅度(16.9%±2.5%)明显高于NERD-H组、EE组(11.8%±2.8%、6.4%±1.0%,均P<0.05).结论 在食管内脏高敏感状态下,中枢神经系统处理整合、处理食管痛敏传入信息功能异常.%Objective To investigate the brain mechanisms for esophageal visceral hypersensitivity. Methods Thirty-one non-erosive reflux disease(NERD)patients, 21 in the group of NERD with esophageal

  16. 严重延迟复苏烧伤休克患者血浆脑钠肽的变化%Change in plasma brain natriuretic peptide and its clinical significance in burn patients after delayed fluid resuscitation of shock

    Institute of Scientific and Technical Information of China (English)

    黄永新; 詹新华; 郑静伟; 吴祖煌; 陈建崇; 朱剑仙; 谢包根; 刘世康

    2010-01-01

    伤后72 h30.28±7.13、伤后168 h 21.44±3.15,心衰组分别为65.76±16.38、81.46±7.92、86.43±14.19、72.53±11.27、36.39±6.18、22.85±7.26)的变化比较差异无统计学意义(均P>0.05).结论 血浆BNP浓度测定可作为严重烧伤休克复苏时检测心衰的一项简便易行的有效方法.

  17. Chemistry%化学

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    O612 01050129 具有微孔/大孔双孔道体系沸石材料的合成=Synthesis of Silicate Materials with Micro/Macroporous Bimodal Pore Systems[刊, 中]/王亚军(复旦大学),唐颐…∥高等学校化学学报.&2000, 21(7).&1013~1015 国家自然科学基金(29873011)资助 O612 01050130 一种新型磷酸钛大单晶的溶剂热法合成与结构研究=Studies on Solvothermal Synthesis and Structure of a New Titanium Phosphate Large Single Crystal[刊, 中]/郭阳虹(吉林大学),施展…∥高等学校化学学报.&2000, 21(7).&1010~1012 国家自然科学基金(29571011)资助 O613 01050131 一种氟气源的制备及热分解=Preparation and Thermal Decomposition of a Kind of Fluorine Source[刊, 中]/刘文元(西北核技术研究所),李辉…∥应用化学.&2000, 17(3).&300~303 国家"八六三”计划资助课题 O613 01050132 铒在HBTMPTP-正庚烷/水溶液间的传质动力学=Mass Transfer of Er(Ⅲ) between HBTMPTP Dissolved in n-Heptane and HAc-NaAc[刊, 中]/乐善堂(中科院长春应用化学所),马根祥…∥高等学校化学学报.&2000, 21(6).&832~835 在(30±0.5)℃下,用层流恒界面池研究了铒在HBTMPTP-正庚烷-0.2mol/L(H,Na)Ac萃取体系中的传质动力学.测定了该体系的界面张力,考察了水相酸度、萃取剂浓度、氯离子浓度、温度和比界面对萃取速率的影响.图6参16 国家自然科学基金(29771028,29801004)资助 O613 01050133 岩石中硼的提取分离及同位素组成的测定=Extraction and Separation of Boron in Rock Samples and lts lsotopic Determination by Thermal lonization Mass Spectrometry[刊, 中]/王刚(中科院青海盐湖所),王蕴慧…∥岩矿测试.&2000, 19(3).&169~172 介绍了一种用Na2CO3+K2CO3混合熔剂对岩石样品进行分解,用硼特效树脂和阴、阳混合离子交换树脂相结合进行岩石样品中硼的纯化分离的方法.采用该方法从岩石样品中提取、分离出来的硼能满足硼同位素质谱法测定的需要,不产生硼同位素分馏,硼同位素测定精度大多优于0.05%.表3参7 国家自然科学基金(29775028)资助 O614 01050134 有机/无机纳米杂化材料负载钛催化剂及聚合研究:Ⅰ.乙烯聚合=Study of Titanium Catalysts Supported on he Organic/Inorganic Hybrid and Polymerization Thereby:Ⅰ.Polymerization of Ethylene[刊, 中]/朱宁(中科院长春应用化学所),唐涛…∥应用化学.&2000, 17(3).&233~237 以苯乙烯与马来酸酐无规共聚物为有机组分,以正硅酸乙酯为无机组分,利用sol-gel方法制得纳米杂化材料,以此为载体合成了杂化材料载体钛系催化剂.图3表3参13 国家自然科学基金(29774028)资助 O614 01050135 硫酸锌与L-α-缬氨酸固体配合物的合成与表征=Synthesis and Characterization of Zinc Sulfate Complexes with L-α-Valine[刊, 中]/张晓玉(西北大学),杨旭武…∥应用化学.&2000, 17(3).&243~247 用半微量相平衡方法研究了ZnSO4-Val-H2O体系在25℃时的溶度图及饱和溶液折光率曲线.体系中未形成新化合物.合成了配合物Zn(Val)SO4*H2O、Zn(Val)2*H2O,并进行了表征.图2表3参13 国家自然科学基金(29871023)资助 O614 01050136 微乳液法制备超细包裹型铁粉=Preparation of Ultrafine Fe Particles by Microemulsion Method[刊, 中]/张朝平(贵州大学),邓伟…∥应用化学.&2000, 17(3).&248~251 应用W/O型微乳液法制备了纳米量级包裹型超细铁粉.由XRD、SEM、TEM和IR谱测试表明:它属于表面活性剂包裹型超细微粒.图3参9 国家自然科学基金(19872021)资助 O614 01050137 以12-钨(钼)磷杂多酸为掺杂剂的导电聚N,N-二甲基苯胺的合成与导电性=Synthesis and Conductivity of Conducting Poly N,N-Dimethaniline Doped by 12-Tungsto(Molybdo) Phosphoric Acid Used as Doping Agent[刊, 中]/张贞文(湖北大学),柳士忠…∥湖北大学学报(自然科学版).&2000, 22(3).&270~273 以12-钨(钼)磷杂多酸为掺杂剂,合成了聚N,N-二甲基苯胺.并利用ICP、元素分析、循环伏安、红外光谱及室温固体电导率的测定等手段进行了表征.结果表明,掺杂的PDMAn/PM12的室温导电率约为12-13 S/cm.图3参6 国家自然科学基金(29971010)资助 O614 01050138 Co(phen)2TATP3+与DNA在旋转金盘金环电极上的相互作用研究=Electrochemical Studies on the Interactions of the Complex of Co(phen)2TATP3+ with DNA at Rotating Au-Au Electrode[刊, 中]/李红(中山大学),蒋雄…∥高等学校化学学报.&2000, 21(7).&995~998 在pH=7.2的Tris缓冲溶液中,利用旋转环盘电极法研究了金电极上Co(phen)2TATP3+与DNA的相互作用,并根据扩散控制和电化学控制下得到的各种参数,对它们作用的模式进行了讨论.图3表2参13 国家自然科学基金(29871036)资助 O614 01050139 双金属杂原子分子筛CrCoBEA的合成、波谱及催化性能研究=Studies on the Synthesis, Spectroscopy and Catalytic Properties of CrCoBEA Metallosilicate[刊, 中]/王亚军(南开大学),唐祥海…∥高等学校化学学报.&2000, 21(7).&999~1004 采用水热晶化法首次合成出BEA结构含铬、钴双金属杂原子分子筛CrCoBEA,对晶化时间、晶化温度、成胶配比等合成条件进行了优化研究,测试其物相、波谱性质和催化性能.图6表1参15 国家自然科学基金重点项目(29733070)资助 O614 01050140 Ru(bpy)2+3在MCM-48中的组装及其发光性质=The Assembly of Tris(Bipyridine)Ruthenium(Ⅱ) in MCM-48 and Photoluminescent Properties of Assembly Products[刊, 中]/房铭(吉林大学),张萍…∥高等学校化学学报.&2000, 21(7).&1016~1017 国家自然科学基金(29771013,59795006)资助 O621 01050141 2-烯丙基-1,1-偕二金属环已烷的合成研究=Synthesis of 2-Allyl-1,1-Gemdimetallic Cyclohexane[刊, 中]/宋国强(江苏石油化工学院),王钒…∥合成化学.&2000, 8(3).&216~219 在无水乙醚中1-锂代环己烯和烯丙基溴化镁于无水溴化锌作用下发生金属化克兰荪重排反应,生成2-烯丙基-1,1-偕二金属环己烷.通过对温度、溶剂量和投料顺序等重排反应主要影响因素的考察和优化,可使2-烯丙基-1,1-偕二金属环己烷的收率达到65%.图2表3 国家自然科学基金(2947043)资助 O621 01050142 沙丘芦苇特有一小分子化合物及其对叶绿体的逆境保护效应[刊, 中]/浦铜良(兰州大学),程佑发…∥科学通报.&2000, 45(12).&1308~1313 用柱层析手段从沙漠地区沙丘芦苇叶片中分离得到一种为该生态型所特有的小分子物质,其化学特征与已报道的逆境胁迫诱导累积的溶质均不同,具多氨基芳香族强极性特征.其自然丰度与月平均气温和月极端高温值为指标的生境高温程度呈显著相关性.并主要存在于光合细胞器叶绿体中.该物质对离体叶绿体在高温下电子传递链的功能具有保护作用.图5表2参15 国家自然科学基金(39870062)资助 O621 01050143 亚胺氧自由基与酚类的反应=The Reaction of Iminoxy Radical with Phenols[刊, 中]/胡家欣(南京大学),吉民…∥高等学校化学学报.&2000, 21(7).&1045~1047 研究了亚胺氧自由基与酚类的反应,一步合成了取代苯并C023唑、萘并及喹啉并C023唑类衍生物,同时探讨了反应机理.表2参8 国家自然科学基金(29375052)资助 O621 01050144 新型磺酰胺类含氮手性配体的合成、晶体结构及催化苯乙酮的不对称氢转移反应=Studies on the Synthesis of New Sulfonylamide Ligand, Crystal Structure and Asymmetric Hydrogen Transfer Reaction of Acetophenone[刊, 中]/董春娥(中科院成都有机化学所),张俊龙…∥高等学校化学学报.&2000, 21(7).&1070~1072 国家自然科学基金(29973042)资助 O624 01050145 P+7原子团簇及其特殊配位=P+7 Clusters and Their Specical Coordinations[刊, 中]/陈明旦(厦门大学),罗海彬…∥厦门大学学报(自然科学版).&2000, 39(3).&341~346 在激光产生的磷原子团簇正离子的质谱图中,P+7具有最强的谱峰.使用分子图形软件设计出24种P+7的同分异构体,并进行分子力学、PM3半经验量子化学和ADF密度泛函优化.从各异构体成键能量的比较中可得知,最稳定的P+7构型是在最稳定的P6的双键位置增加1个磷原子所生成的结构.图2表2参23 国家自然科学基金资助 O626 01050146 硫醚双酐聚酰胺酸的合成及其热稳定性=The Synthesis and Thermal Stability of Thioether Dianhydride Poly(Amic Acid)[刊, 中]/王江洪(中科院感光化学所),沈玉全∥高等学校化学学报.&2000, 21(6).&879~883 合成了硫醚二酐和4-硝基-4′-[N,N-二(2-氨乙基)氨基]偶氮苯(二胺单体)及对应的硫醚聚酰胺酸,并对其结构进行表征.目前,这些聚合物在高敏感非线性光学材料方面显示着广泛的应用前景.图3参14 国家自然科学基金(69637010)资助 O626 01050147 具有光致变色和发光性能的有机化合物的合成及其性能研究=Synthesis and Characteristics of Compounds Having Both Photochromic and Fluorescent Character[刊, 中]/庞美丽(南开大学),王永梅…∥高等学校化学学报.&2000, 21(6).&903~907 以吲哚啉螺苯并吡喃与香豆素衍生物为原料.用DCC缩合酯化法在温和条件下合成了8种新的具有光致变色和发光性能的化合物.所得化合物同时具有光致变色和发荧光的双重特性.图2参15 国家自然科学基金(29872015)资助 O626 01050148 1,2,4-三唑并[3,2-d][1,5]-苯并氧氮杂C024化合物的合成=Synthesis of 1,2,4-Triazolo[3,2-d][1,5] Benzoxazepine Compounds[刊, 中]/刘现军(复旦大学),刘毅…∥高等学校化学学报.&2000, 21(7).&1052~1055 苯并二氢吡喃-4-酮的芳腙衍生的偶氮基碳正离子与腈发生1,3-偶极环加成反应,加成产物通过[1,2]-迁移扩环重排反应,形成新颖的三环系杂环化合物1,2,4-三唑并[3,2-d][1,5]-苯并氧氮杂C024化合物.图1表3参9 国家自然科学基金(A29872007)资助 O626 01050149 四(4-N-吡啶基)卟啉衍生物的合成及表征=Synthesis and Characterization of Meso-Tetrakis(4-Pyridyl) Porphyrin Derivatives[刊, 中]/刘淑清(吉林大学),孙浩然…∥应用化学.&2000, 17(3).&260~263 利用吡啶氮烷基化合成了一系列具有空间效应的水溶性和油溶性的四(4-N-吡啶基)卟啉衍生物及其对应的金属钴卟啉.表5参8 国家自然科学基金(29733090,29803003)资助 O627 01050150 η6-苯乙烯二羰基(三苯基膦)铬配合物的合成与聚合=Synthsis and Polymerization of η6-Styrenedicarbonyl (Triphenylphos- phine) Chromium Complexes[刊, 中]/田晓慧(华东理工大学),林嘉平…∥功能高分子学报.&2000, 13(4).&419~422 国家教委留学回国人员科研启动基金资助 O627 01050151 Schiff碱单核及双核配合物拟酶催化性能的研究=Studies on the Biomimetic Catalytic Character of New Schiff Base Mono-and Di-Nuclear Complexes[刊, 中]/陈新斌(湖南大学),朱申杰…∥高等学校化学学报.&2000, 21(7).&1048~1051 国家自然科学基金(29472055)资助 O627 01050152 Cp2TiCl2/BuiMgBr/THF体系还原二芳基二硒醚=Reduction of Diphenyldiselides with Cp2TiCl2/BuiMgBr/THF[刊, 中]/许新华(南开大学),黄宪∥高等学校化学学报.&2000, 21(7).&1073~1074 国家自然科学基金(29672008)资助 O629 01050153 环肽合成方法的研究进展=Progress in the Study on Synthetic Method of Cyclopeptide[刊, 中]/唐艳春(北京大学),田桂玲…∥高等学校化学学报.&2000, 21(7).&1056~1063 介绍了纯环肽与杂环肽合成的方法、策略及其优缺点,列举了一些常用缩合试剂,探讨了反应溶液浓度、线型肽前体化合物的结构及构象等因素对环化反应的影响.参64 国家自然科学基金(29772001)资助 O63 01050154 N-异丙基丙烯酰胺/N-乙烯基吡咯烷酮水凝胶的研究=Synthesis and Characterization of Copolymer Hydrogels of Poly(N-Isopropylacrylamide-co-N-Vinyl-2-Pyrrolidone)[刊, 中]/刘郁杨(西北工业大学),范晓东…∥功能高分子学报.&2000, 13(4).&380~384 陕西省自然科学基金资助 O63 01050155 组织工程细胞支架及其细胞亲和性改进研究进展=Cells Scaffold for Tissue Engineering and Improvement of Cells Affinity between the Cells and Cells Scaffold[刊, 中]/杨健(中科院化学所),贝建中…∥功能高分子学报.&2000, 13(4).&455~460 国家"973计划” O63 01050156 新型的乙烯聚合催化剂=Novel Catalysts for Ethylene Polymerization[刊, 中]/罗祥(中山大学),伍青∥功能高分子学报.&2000, 13(4).&481~486 广东省自然科学基金资助 O631 01050157 衣康酸对聚丙烯腈原丝结构和性能的影响=Effect of Itaconic Acid on the Structure and Properties of PAN Precursor[刊, 中]/张旺玺(山东工业大学)∥高分子学报.&2000, (3).&287~291 控制单体配比,采用丙烯腈与衣康酸自由基溶液共聚,以偶氮二异丁腈为引发剂在溶剂二甲基亚砜中合成了聚丙烯腈原丝纺丝溶液,并纺制了碳纤维前驱体聚丙烯腈原丝.通过元素分析、IR、DSC、13C-NMR等手段,讨论了共聚单体衣康酸对共聚反应及聚丙烯腈原丝结构和性能的影响.图3表3参11 国家自然科学基金(59783002)资助 O631 01050158 Cr(Ⅱ)与过氧化莰烷酮酰体系引发的活性自由基聚合反应研究=Study on "Living” Radical Polymerization Initiated by Aged Chronum (Ⅱ) Acetate and Ketopinyl Peroxide[刊, 中]/李增昌(中国科学技术大学),吴承佩…∥高分子学报.&2000, (3).&330~334 合成了过氧化莰烷酮酰(KPO),用它和Cr(Ac)2组成的氧化还原体系经陈化后,引发甲基丙烯酸甲酯,甲基丙烯酸β-羟乙酯和丙烯酸进行了聚合反应.其中甲基丙烯酸甲酯具有活性聚合特征.并有效引发含羟基单体如甲基丙烯酸β羟乙酯和丙烯酸进行聚合.图2表4参10 国家自然科学基金(29774027)资助 O631 01050159 MgCl2负载(dbm)2Ti(OPh)2催化乙烯聚合=Ethylene Polymerization with MgCl2-Supported(dbm)2Ti(OPh)2[刊, 中]/阎卫东(中科院化学所),洪瀚…∥高分子学报.&2000, (3).&358~360 报道了用MgCl2负载的二苯氧基二(二苯甲酰甲烷)钛铬合物(dbm)2Ti(OPh),以甲基铝氧烷为助催化剂,常压催化乙烯聚合的结果.图1表2参8 国家自然科学基金(29734141)重点资助 O631 01050160 单分散聚苯乙烯乳胶有序膜在二氧化硅多孔材料制备中的模板作用=Template Effects of the Ordered Film Formed from Monodispersed Polystyrene Latex[刊, 中]/杨振忠(中科院化学所),齐凯…∥高分子学报.&2000, (3).&364~367 以单分散聚苯乙烯乳胶室温形成的有序膜为模板,采用快速溶胶凝胶方法,制备了聚苯乙烯/二氧化硅杂化物,高温烧蚀除去有机物得到了二氧化硅有序孔材料,并讨论了聚苯乙烯有序膜的模板作用机理.图5参15 国家自然科学基金(29774038)资助 O631 01050161 新型含环氧端基聚芳醚酮的合成及表征=Synthesis and Characterization of a Novel Epoxy-Terminated Poly(Aryl Ether Ketoe)[刊, 中]/宣英男(大连理工大学),蹇锡高…∥高分子学报.&2000, (4).&407~410 国家"九五”攻关项目 O631 01050162 超支化聚(胺-酯)的分子设计及其制备=Synthesis and Characterization of Hyperbranched Poly(Amine-Ester)[刊, 中]/陆玉(中国科学技术大学),林德…∥高分子学报.&2000, (4).&411~414 国家自然科学基金(59673026)资助 O631 01050163 聚苯基单醚喹C023啉薄膜的性能与物理老化=The Relations between Properties and Physical Aging of Polyphenylquinoxaline Film[刊, 中]/刘万军(中科院化学所),沈静姝…∥高分子学报.&2000,(4).&415~419 国家科委基础性研究重大项目 O631 01050164 端基附壁模型聚合物环形链的构象统计理论=Configurational Statistics of Model Polymer Loop Chains Attached to a Surface[刊, 中]/廖琦(四川大学),吴大诚∥高分子学报.&2000,(4).&420~425 国家自然科学基金(29774016)资助 O631 01050165 拉格朗日-欧拉方法模拟高分子复杂流体平面收缩流动=The Lagrangian-Eulerian Method:Solutions for Planar Contraction Flow[刊, 中]/李险峰(中科院化学所),袁学锋…∥高分子学报.&2000,(4).&432~437 国家自然科学基金(29634030)资助 O631 01050166 气体膜分离用过渡金属有机络合物-聚酰亚胺杂化材料的研究=Study on Transitional Metal Organic Complex-Polyimide Hybrid Material for Gas Separation Membranes[刊, 中]/史德青(石油大学),孔瑛…∥高分子学报.&2000,(4).&457~461 科技部国家重点基础研究发展规划项目 O631 01050167 原子转移自由基聚合制备聚(丙二醇-g-苯乙烯)=Synthesis of Poly(Propylene Glycol-g-Styrene) from Atom Transfer Radical Polymerization[刊, 中]/黄昌国(华东理工大学),万小龙…∥高分子学报.&2000,(4).&467~471 国家自然科学基金(29634010)资助 O631 01050168 聚苯胺嵌入氧化石墨复合物的合成及表征=Synthesis and Characterization of Polyaniline Intercalated Graphite Oxide Composite[刊, 中]/刘平桂(北京航空材料研究院),龚克成∥高分子学报.&2000,(4).&492~495 国家自然科学基金(59836230)资助 O631 01050169 乙交酯/丙交酯共聚物的体内外降解行为及生物相容性研究=Study on the Biocompatibility and Degradation Behavior of Poly(l-Lactide-co-Glycolide) in vitro and in vivo[刊, 中]/蔡晴(中科院化学所),贝建中…∥功能高分子学报.&2000, 13(3).&249~254 国家重点基础研究发展规划(973)资助 O631 01050170 动态下HTDB/TDI体系凝胶化的研究=Study on the Gelation of Hydroxy-Teminated Polybutadiene/Diisocyanate Blends under Dynamic Condition[刊, 中]/邱方正(华东理工大学),陈建定∥功能高分子学报.&2000, 13(3).&289~292 国家教育部博士点基金资助 O631 01050171 含偶氮苯生色团的聚醚的合成与热致液晶性质=Synthesis and Thermotropic Liquid Crystalline Properties of Two Polyethers Containing Azobenzene Groups[刊, 中]/梁旭霞(中山大学),张灵志…∥功能高分子学报.&2000, 13(3).&277~284 广东省自然科学基金资助 O631 01050172 CoSalphen在壳聚糖上的固定化及对DOPA的催化氧化研究=CoSalphen Immobilized onto Chitosan and Its Activate in Catalytic Oxidation of DOPA[刊, 中]/马会宣(陕西师范大学),胡道道…∥功能高分子学报.&2000, 13(3).&301~305 陕西省自然科学基金资助 O631 01050173 环氧基活化凝胶的开环反应=Ring-Opening Reaction on Epoxy-Activated Resin[刊, 中]/查娟(生物反应器工程国家重点实验室),刘坐镇…∥功能高分子学报.&2000, 13(3).&321~324 由自制的乙酸乙烯酯-甲基丙烯酸缩水甘油酯-甲基丙烯酸烯丙酯大孔共聚物与氨水反应,实现了环氧基的开环反应.考查了不同的氨水浓度、反应温度和时间对胺化转化率的影响,并测定了形成的伯胺基的pKa值为6.9.图4表1参12 国家自然科学基金(29706002)资助 O631 01050174 纳米自组装聚电解质超薄多层膜=Polyelectrolyte Ultrathin Multilayer Films by Nano-Self-Assembly Process[刊, 中]/孙启龙(华南理工大学),王朝阳∥功能高分子学报.&2000, 13(3).&332~336 国家杰出青年科学基金(29725411)与国家自然科学基金(29804003)资助 O631 01050175 十二烷基硫酸钠减慢二苯胺-4-重氮盐及重氮树脂在水溶液中热分解反应的机理=The Mechanism of Thermal Decomposition of DDS and DR in Aqueous Solution Delayed by SDS[刊, 中]/杨伯C025(北京大学),曹维孝∥高等学校化学学报.&2000, 21(6).&969~975 国家自然科学基金(59633110及29774001)资助 O631 01050176 芘标记磺酸基聚电解质在水与DMSO中的荧光光谱=Fluorescence Spectra of Pyrene Labeled Polyelectrolytes with Sulfonate Groups in Water and DMSO[刊, 中]/高峰(华南理工大学),严宇…∥高等学校化学学报.&2000, 21(6).&976~979 国家自然科学基金(29804003)与国家杰出青年科学基金(29725411)资助 O631 01050177 尼龙1012的Brill转变=Brill Transition of Nylon 1012[刊, 中]/李勇进(上海交通大学),颜德岳…∥高等学校化学学报.&2000, 21(6).&983~984 国家自然科学基金(29974017)资助 O631 01050178 热致液晶含氯侧基聚芳醚酮的单晶状条带织构=The Single Crystal-Like Banded Textures in the Films of a Thermotropic Liquid Crystalline Poly(Aryl Ether Ketone) Containing a Lateral Chloro Group[刊, 中]/富露祥(中科院长春应用化学所),张善举…∥高等学校化学学报.&2000, 21(6).&988~990 国家自然科学基金(29974032)资助 O631 01050179 具有RAFT链转移过程的活性自由基聚合的Monte Carlo模拟=Monte Carlo Simulation on Living Radical Polymerization with RAFT Process[刊, 中]/李莉(复旦大学),何军坡…∥高等学校化学学报.&2000, 21(7).&1146~1148 国家自然科学基金资助 O631 01050180 C60-苯乙烯-顺丁烯二酸酐的三元自由基共聚=Free Radical Ternary Copolymerization of C60 with Styrene and Maleic Anhydride[刊, 中]/官文超(华中理工大学),雷洪…∥高等学校化学学报.&2000, 21(7).&1149~1150 国家自然科学基金(29674010)资助 O631 01050181 聚(苯乙烯-b-2-甲基-2-C023唑啉)嵌段共聚物的合成=Studies on Synthesis of P(S-b-Me-OXZ) Block Copolymers[刊, 中]/刘燕飞(华东理工大学),万小龙…∥高等学校化学学报.&2000, 21(7).&1157~1159 国家自然科学重点基金(29634010-2)资助 O631 01050182 乙丙共聚物接枝马来酸酐反应机理的模拟研究=Investigation of Reaction Mechanism of Maleic Anhydride Grafted onto Ethylene-Propylene Copolymer[刊, 中]/黄宏亮(中科院长春应用化学所),姚占海…∥应用化学.&2000, 17(3).&256~259 国家自然科学基金(59873022)资助 O631 01050183 稀土催化丁二烯-异戊二烯共聚合过程中的原位环化反应=In situ Cyclization in the Course of Butadiene Isoprene Copolymerization with Nd-Based Catalyst[刊, 中]/董为民(中科院长春应用化学所),逄束芬…∥应用化学.&2000, 17(3).&272~275 国家自然科学基金(29574179)资助 O631 01050184 计算机模式识别在颜料表面改性中的应用=Study on the Application of Pattern Recognition with a Computer in Surface Modification of Pigment[刊, 中]/严乐美(天津大学),杨桂琴…∥天津大学学报.&2000, 33(3).&344~347 国家自然科学基金(29376254)资助 O631 01050185 共混物中聚氯乙烯凝胶化度测试=Studies on Gelling Value of Polyvingyl Chloride in the Blend[刊, 中]/何本桥(湖北大学),张玉红…∥湖北大学学报(自然科学版).&2000, 22(4).&367~370 湖北省自然科学基金资助 O631 01050186 二氧化硅模板技术制备三维有序聚苯乙烯孔材料[刊, 中]/容建华(中科院化学所),杨振忠…∥科学通报.&2000, 45(15).&1627~1630 以单分散二氧化硅颗粒形成的有序结构为模板,制备了聚苯乙烯孔材料.通过扫描电子显微镜观察了模板、复合物及有序多孔聚苯乙烯的形态.结果表明,所合成的多孔材料中,孔大小均匀,空间排布高度有序,且结构与模板中二氧化硅小球自组装方式完全相同.图6参8 国家自然科学基金(20023003)资助 O631 01050187 光导性偶氮聚合物材料的设计[刊, 中]/周雪琴(浙江大学),陈红征…∥自然科学进展.&2000, 10(6).&543~548 以电荷转移理论为指导,对偶氮聚合物材料结构进行设计,获得了两类光导性偶氮聚合物材料,并对其结构和光导性进行了分析与讨论.图4表1参16 国家自然科学基金(59333071,69890230)资助 O631 01050188 聚合物复合材料中填料的摩擦学作用=Tribological Actions of Filiers in Polymer Composites[刊, 中]/薛群基(中科院兰州化学物理所),阎逢元∥中国科学基金.&2000, 14(4).&211~215 综述了就填料对聚合物复合材料的结构和摩擦学行为的影响,并对目前研究过程中所存在的问题进行了简要分析.图3参29 国家自然科学基金资助 O633 01050189 双马来酰亚胺树脂链结构对熔点和反应活性的影响=The Effect of Chain Structure of Bismaleimide Resins on Melting Point and Reactivity of Reaction[刊, 中]/刘润山(湖北省化学研究所),赵三平…∥功能高分子学报.&2000, 13(4).&487~493 湖北省自然科学基金资助 O636 01050190 高分子固体电解质材料研究进展=Advances in Material of Solid Polymer Electrolytes[刊, 中]/赵地顺(河北科技大学),孙凤霞…∥功能高分子学报.&2000, 13(4).&469~475 河北省自然科学基金资助 O64 01050191 Ru(bpy)2(NCS)2染料敏化CdS/Zn2+-TiO2复合半导体纳米多孔膜的光电化学=Photoelectrochemistry of CdS/Zn2+-TiO2 Composite Semiconductor Nanoporous Films Sensitized by Ru-(bpy)2(NCS)2 Dye[刊, 中]/张莉(北京大学),王艳芹…∥高等学校化学学报.&2000, 21(7).&1075~1079 国家自然科学基金(29773003)资助 O641 01050192 富勒烯笼结构的平面展示法[刊, 中]/叶大年(中科院地质与地球物理所),艾德生…∥科学通报.&2000, 45(16).&1781~1785 采用船式F5和F6与海燕式F5和F6分别表示富勒烯笼几何结构的两种平面图.这些平面图最大的优点是:(1)不破坏富勒烯笼的空间对称性;(2)可以非常清楚地展示出结构中F5和F6的配位形式.这为富勒烯笼的结构几何研究打下了基础.图3参17 国家自然科学基金(49872019)资助 O641 01050193 布朗扩散系数对胶体分形粒子簇扩散控制聚集动力学影响的Monte Carlo模拟=Monte Carlo Simulation to the Effect of Cluster Brownian Diffusion Coefficient on the Colloidal Fractal Cluster Aggregation Kinetics[刊, 中]/王惠(南开大学),王贵昌…∥高等学校化学学报.&2000, 21(6).&922~925 使用表征粒子簇结构的几何形状因子,通过对扩散控制聚集过程的模拟,从微观或介观层次研究了粒子簇结构对粒子簇增长速率和速率常数的影响规律,并与实验结果进行了对比分析.图4表1参15 国家自然科学基金(29573109)资助 O641 01050194 一些富勒烯C60双加成物稳定性的理论研究=Theoretical Studies on the Stabilities of Some C60 Bis-Adducts[刊, 中]/陈中方(南开大学),王贵昌…∥高等学校化学学报.&2000, 21(7).&1127~1129 国家自然科学基金(29773022)资助 O641 01050195 M(bpy)+32(M=Fe,Ru,Os)电子结构与相关性质=Electronic Structure and Related Chemical Properties of Complexes(M=Fe,Ru,Os)[刊, 中]/郑康成(中山大学),匡代彬…∥物理化学学报.&2000, 16(7).&608~612 报道了对配合物(M=Fe,Ru,Os)的量子化学密度泛函法研究的结果,探讨的电子结构特征及相关性质,特别是中心原子对配合物的配位键长、光谱性质、电荷布居及化学稳定性等的影响规律.图2表6参14 国家自然科学基金资助 O642 01050196 纳米HZSM-5分子筛的热稳定性=Thermostability of Nanosized HZSM-5 Zeolite[刊, 英]/张维萍(中科院大连化物所),包信和∥催化学报.&2000, 21(3).&195~196 科技部攀登计划项目 O642 01050197 微量热法研究硒对大肠杆菌生长代谢的作用=Microcalorimetric Study of the Action of Seleniumcontaining Complexes on Growth Metabolism of Escherichia coli[刊, 中]/李曦(武汉大学),刘义…∥物理化学学报.&2000, 16(6).&568~572 采用微量热法测定了Na2SeO3、吗啉、硒代吗啉和N,N'-亚基双硒代吗啉对大肠杆菌作用的热功率输出曲线,根据热功率输出曲线求算在这些药物作用下,大肠杆菌生长代谢的速率常数,并对它们的作用特征进行了比较.图2表1参7 国家自然科学基金资助 O642 01050198 反相气相色谱法测定溶剂在PBMA中的无限稀释活度系数=Measurement of Infinite Diluted Activity Coefficient of Solvent in PBMA by Inverse Gas Chromatography Method[刊, 中]/冯媛媛(华东理工大学),叶汝强…∥华东理工大学学报.&2000, 26(3).&305~308 用反相气相色谱方法测定了16种溶剂在聚甲基丙烯酸丁酯(PBMA)中343~433K范围内的无限稀释活度系数,并用周浩等的高分子溶液分子热力学模型对实验结果进行了关联,结果令人满意.图8表2参15 国家自然科学基金(29976011)资助 O643 01050199 海泡石对非晶态NiB合金催化剂的改性研究=Studies on the Modification of Sepiolite for Amorphous NiB Alloy Catalyst[刊, 中]/石秋杰(南昌大学),陈昭萍…∥物理化学学报.&2000, 16(6).&501~506 以常压气相苯加氢为探针反应,考察了酸改性前后海泡石的加入对非晶态NiB合金催化剂的加氢及抗硫性能的影响,用TPR、TPD表征了催化剂的表面性质,测定了酸改性前后海泡石的比表面及孔径分布,并与活性进行了关联.图3表3参12 国家自然科学基金资助 O643 01050200 F+NCO反应的机理和动力学=Mechanism and Kinetics of the F+NCO Reaction[刊, 中]/侯华(山东大学),王宝山…∥物理化学学报.&2000, 16(6).&517~521 高等学校博士学科点专项科研基金资助 O643 01050201 激光溅射下原子团簇生长的非平衡力学(Ⅱ)=Non-Equilibrium Kinetics of Clusters Growth under Laser Ablation(Ⅱ)[刊, 中]/曹玉群(厦门大学),黄荣彬…∥物理化学学报.&2000, 16(7).&621~626 国家自然科学基金(29890210,29773040)资助 O643 01050202 双(2,4-二甲基戊二烯基)氯化钆的合成及晶体结构=Synthesis and Structure of Bis(2,4-Dimethylpentadienyl)Gadolinium Chloride[刊, 中]/王建辉(吉林大学),母瀛…∥高等学校化学学报.&2000, 21(6).&829~831 国家自然科学基金(29672013,29754143)资助 O643 01050203 温控相转移催化&&水/有机两相催化新进展=Thermoregulated Phase-Transfer Catalysis&&Recent Advances in Water/Organic Biphasic Catalysis[刊, 中]/金子林(大连理工大学),梅建庭…∥高等学校化学学报.&2000, 21(6).&941~946 综述了"温控相转移催化”的原理,温控膦配体的设计、合成及其在水溶性极小的底物高碳烯烃的水/有机两相氢甲酰化反应中的应用效果.图4表5参35 国家自然科学基金(29792074)资助 O643 01050204 Cr-HMS合成、表征及其在催化氧化反应中的应用=Synthesis, Characterization of Cr-HMS and the Application in Catalytic Oxidation[刊, 中]/乐洪咏(复旦大学),华伟明…∥高等学校化学学报.&2000, 21(7).&1101~1104 合成了一系列不同Cr含量的Cr-HMS介孔分子筛,并对其物化性质进行了表征.结果表明,Cr的引入降低了介孔分子筛骨架结构的规整度和孔径的均一程度.Cr-HMS对苯羟基化和环己烷氧化反应均表现出良好的催化活性.并且随Cr含量的增加,催化活性呈火山型分布.图3表3参14 国家自然科学基金(29873011)资助 O643 01050205 新型甲烷无氧芳构化催化剂MoO3/MCM-49=A Novel Catalyst of MoO3/MCM-49 over Nonoxidative Aromatization of CH4[刊, 中]/许宁(吉林大学),阚秋斌…∥高等学校化学学报.&2000, 21(7).&1113~1114 国家自然科学基金(29973011)资助 O643 01050206 以TiCl4为钛源合成钛硅分子筛=Synthesis of Titanosilicalite Using Titanium Tetrachloride as Titanium Source[刊, 英]/张义华(大连理工大学),王祥生∥催化学报.&2000, 21(3).&197~198 以四丙基溴化铵为模板剂,以四氯化钛为钛源,研究了合成小晶粒钛硅分子筛(TS-1)的合成路线.合成的TS-1样品在丙烯环氧化反应中显示有较高的活性(96%)和选择性(95%),H2O2利用率高于95%.图3表1参8 国家自然科学基金(29792071)资助 O643 01050207 稀土氧化物在Fe1-xO基氨合成催化剂中的作用规律=Regular Effect of Rare Earth Oxide on Fe1-xO Catalyst for Ammonia Synthesis[刊, 中]/季德春(浙江工业大学),李小年∥催化学报.&2000, 21(3).&199~203 考察了稀土氧化物对Fe1-xO基催化剂性能的影响.结果表明,稀土氧化物与Fe1-xO作用生成一种复合氧化物REFeO3,从而促进了催化剂的还原,这种促进作用随稀土离子半径不同呈现规律性变化.图1表6参14 国家自然科学基金(29706011)资助 O643 01050208 光电催化降解磺基水杨酸的研究=Study of Photoelectrocatalytic Degradation of Sulfosalicylic Acid[刊, 中]/刘鸿(中科院大连化学物理所),冷文华∥催化学报, 21(3).&209~212 建立了以TiO2/Ni为工作电极、泡沫镍为对电极、饱和甘汞电极为参比电极的光电催化反应体系,研究了在磺基水杨酸(SSal)的光电催化降解过程中,外加电压和溶液pH值对降解速率的影响.图5表1参18 国家自然科学基金(29877024)资助 O643 01050209 多孔TiO2薄膜的表面微结构对甲基橙光催化脱色的影响=Effect of Surface Microstructure of Porous TiO2 Thin Films on Photocatalytic Decolorization of Methyl Orange[刊, 中]/余家国(武汉工业大学),赵修建∥催化学报.&2000, 21(3).&213~216 湖北省自然科学基金资助 O643 01050210 γ-Mo2N催化剂上的乙炔选择加氢=Selective Hydrogenation of Ethyne on γ-Mo2N[刊, 中]/郝志显(中科院大连化学物理所),魏昭彬∥催化学报.&2000, 21(3).&217~220 对γ-Mo2N催化剂上乙炔加氢反应进行了研究.在150℃的反应温度下,乙炔转化率为95%,乙烯选择性达80%,乙烷选择性为4%,丁烯选择性为10%.反应温度和空速对产物的选择性没有明显的影响.图4参17 国家自然科学基金(29625305)资助 O643 01050211 WO3/ZrO2固体强酸催化剂上异丁烷/丁烯的烷基化反应:Ⅱ.过渡金属的助催化作用=Study on Alkylation of Isobutane with Butene over WO3/ZrO2 Strong Solid Acid:Ⅱ. Promotions Effect of Transition Metal[刊, 中]/孙闻东(中科院长春应用化学所),吴越∥催化学报.&2000, 21(3).&229~233 制备了一系列用过渡金属活化的WO3/ZrO2固体强酸催化剂,并对其晶型结构、表面状态和酸量进行了表征.图7表2参22 国家自然科学基金(29792076)资助 O212 01050212 超细镍基催化剂上CH4-CO2重整反应的性能:Ⅰ.制备方法对催化剂结构和还原性能的影响=CH4 Reforming with CO2 over Superfine Ni-Based Catalysts:Ⅰ. Effects of Preparation Methods on Structure and TPR of Catalysts[刊, 中]/许峥(清华大学),张鎏∥催化学报.&2000, 21(3).&234~238 国家博士点基金资助 O643 01050213 SO2对Co3O4/Al2O3选择性催化氧化NO的影响=Effect of SO2 on Catalytic Oxidation of NO over Co3O4/Al2O3[刊, 中]/赵秀阁(华东理工大学),肖文德∥催化学报.&2000, 21(3).&239~242 采用流动态原位IR,TPD及XPS技术研究了NO及SO2在Co3O4/Al2O3金属氧化物催化剂表面上的吸附及脱附行为,并与该催化剂上模拟烟道气中NO的选择性催化氧化活性相关联,考察了SO2对该反应过程的影响及作用机理.图5参13 国家自然科学基金(29633030)资助 O643 01050214 Lewis酸对杂多酸催化异丁烷/丁烯烷基化反应的作用=Effect of Lewis Acid on Alkylation of Isobutane with Butene[刊, 中]/赵振波(中科院长春应用化学所),吴越∥催化学报.&2000, 21(3).&243~246 考察了SbCl5对杂多酸(HPA)催化异丁烷/丁烯烷基化反应的修饰作用,用Hammett指示剂测定了SbCl5/HPA催化剂的酸强度.结果表明,经SbCl5修饰的HPA的酸强度有所提高,SbCl5的加入量、反应温度及反应时间对烷基化油收率及产物分布均有不同的影响.图5表2参15 国家自然科学基金(29792076)资助 O643 01050215 微波固相法制备的ZnCl2/Y在α-蒎烯环氧化物重排反应中的催化性能=Catalytic Performance of ZnCl2/Y Catalyst Prepared by Solid-State Microwave Irradiation for Rearrangement Reaction of α-Pinene Oxide[刊, 中]/尹笃林(湖南师范大学),银董红∥催化学报.&2000, 21(3).&251~254 国家自然科学基金(29572042,29972011)资助 O643 01050216 Co-Mo/HZSM-5甲烷无氧芳构化催化剂上的积炭=Characterization of Coke on Co-Mo/HZSM-5 Catalyst for Methane Dehydro-Aromatization in the Absence of Oxygen[刊, 中]/田丙伦(中科院大连化学物理所),徐奕德∥催化学报.&2000, 21(3).&255~258 国家重点基础研究发展规划项目 O643 01050217 热处理改性的活性炭纤维的脱硫活性=Desulfurization Activity of Activated Carbon Fiber Modified by Heat Treatment[刊, 中]/李开喜(中科院山西煤炭化学所),凌立成∥催化学报.&2000, 21(3).&264~268 考察了在O2和水蒸气存在下高温热处理对活性炭纤维(ACF)催化转化SO2为H2SO4的活性的影响,关联了ACF表面含氧官能团的种类及数量与其脱硫活性之间的关系.图4表2参20 国家自然科学基金(29633030)资助 O643 01050218 制备方法对锶改性氧化铝的高温热稳定性的影响=The Influence of Preparation Methods on the Thermal Stability of Alumina Modified by Strontium[刊, 中]/刘勇(复旦大学),陈晓银∥催化学报.&2000, 21(3).&273~275 福特-中国研究与发展基金资助 O643 01050219 NO在氧化铝负载的Pd催化剂上吸附的TPD-MS研究=TPD-MS Study of NO Adsorption on Alumina Supported Pd Catalysts[刊, 中]/刘振林(中国科技大学),伏义路∥催化学报.&2000, 21(3).&279~282 福特-中国研究与发基金资助项目 O643 01050220 不同焙烧气氛对氟化镁表面碱性的影响=The Effect of Different Calcination Atmosphere on the Surface Basicity of Magnesium Oxide[刊, 中]/孟明(中国科技大学),林培琰∥催化学报.&2000, 21(3).&286~288 在不同气氛中600℃下焙烧Mg(OH)2制得了MgO样品.结果表明,Mg(OH)2经焙烧后分解为MgO.样品的比表面积受焙烧气氛的影响,真空中制备的样品比表面积最大,而空气中制备的样品比表面积最小.真空中制备的样品具有最多的碱位和最强的碱性.图3表2参8 国家自然科学基金(29973037)资助 O643 01050221 Ni改性Cu/Mn/ZrO2催化剂上合成低碳混合醇的研究=Synthesis of Mixed Higher Alcohols by CO Hydrogenation over Ni-Modified Cu/Mn/ZrO2 Catalyst[刊, 中]/陈小平(中科院山西煤炭化学所),吴贵升∥催化学报.&2000, 21(4).&301~304 国家自然科学基金(29873064)资助 O643 01050222 超细镍基催化剂上CH4-CO2重整反应的性能:Ⅱ.制备方法对催化和抗积碳性能的影响=CH4 Reforming with CO2 over Superfine Ni-Based Catalysts:Ⅱ.Effects of Preparation Methods on Reactivity and Carbon Deposition over Catalysts[刊, 中]/许峥(清华大学),张鎏∥催化学报.&2000, 21(4).&309~313 国家博士点基金资助 O643 01050223 合成甲基叔丁基醚的分子筛催化剂研究=A Study of Zeolite Catalysts for Synthesis of Methyl tert-Butyl Ether[刊, 中]/李永红(天津大学),王莅∥催化学报.&2000, 21(4).&323~326 中国石油化工集团公司资助 O643 01050224 二苯并噻吩在CoMoNx催化剂上的加氢脱硫=Hydrodesulfurization of Dibenzothiophene over Cobalt-Promoted Molybdenum Nitride Catalysts[刊, 中]/柳云骐(石油大学),刘晨光∥催化学报.&2000, 21(4).&337~340 中国石油天然气集团公司资助 O643 01050225 锆助剂含量对钴基费-托合成催化剂的影响=Effect of ZrO2 Loadings on Catalytic Performance of Co/SiO2 for F-T Synthesis[刊, 中]/陈建刚(中科院山西煤炭化学所),相宏伟∥催化学报.&2000, 21(4).&359~362 国家重点基础研究发展规划项目 O643 01050226 一种天然气直接转化制乙烯的新过程=A Novel Process for Direct Conversion of Natural Gas to Ethylene[刊, 英]/朱爱民(中科院大连化物所),田志坚∥催化学报.&2000, 21(4).&395~396 国家科技部资助项目 O643 01050227 N,N-二甲基胺乙基膦酸-磷酸氢锆为载体的新型固体碱研究=Study on Solid Base Supported on Zirconium Dimethyl Aminoethylphosphonate-Phosphate[刊, 中]/龚成斌(中科院大连化学物理所),曾仁权…∥应用化学.&2000, 17(3).&264~267 国家自然科学基金资助 O643 01050228 丙烷在钒-磷混合氧化物催化剂上晶格氧氧化及其循环流化床工艺=Oxidation of Propane over Vanadium-Phosphorus Oxides Catalyst by Lattice Oxygen and Its Circulating Fluidized Bed Process[刊, 中]/王鉴(浙江大学),赵如松…∥应用化学.&2000, 17(3).&313~315 用脉冲色谱研究了丙烷在钒-磷混合氧化物催化剂上的选择氧化反应,并结合TPD和XRD表征结果,证明丙烷是与催化剂的晶格氧反应生成丙烯酸和乙酸.图2参5 国家自然科学基金(29676007)资助 O643 01050229 用以分解氟里昂-12的新型催化剂WO3/Al2O3=A Novel Catalyst WO3/Al2O3 for Decomposition of CFC-12[刊, 中]/马臻(复旦大学),华伟明…∥应用化学.&2000, 17(3).&319~321 国家科委攀登计划资助 O643 01050230 LaFeO3的光催化性=Photocatalytic Activity of LaFeO3[刊, 中]/白树林(天津大学),付希贤…∥应用化学.&2000, 17(3).&343~345 采用柠檬酸法和微乳液法制备纳米晶LaFeO3.结果表明,微乳液法较柠檬酸法制备的LaFeO3粒径小,表面积大,使LaFeO3吸附性增加,因此表现出较强的光催化活性.图2表1 国家自然科学基金(59772019)资助 O643 01050231 NiO/SiO2催化剂上CO氧化的反应机理研究=Mechanism of CO Oxidation on NiO/SiO2 Catalyst[刊, 中]/王远洋(宁夏大学),高荫本…∥宁夏大学学报(自然科学版).&2000, 21(2).&147~149 NiO/SiO2是优良的非贵金属型CO氧化催化剂,EXAFS和TPR表征表明其活性中心为NiO.在此基础上的Monte Carlo模拟表明,在NiO/SiO2上CO氧化遵循L-H机理.图5参11 国家自然科学基金(29803009)资助 O643 01050232 烯基取代的茂钛族络合物合成及应用于烯烃催化聚合的进展=Recent Advances in the Synthesis of Alkenyl Substituted Metallocene Complexes(Ti,Zr,Hf) and the Application of Its to α-Olefins Polymerization[刊, 中]/钱贤苗(华东理工大学),许胜…∥功能高分子学报.&2000, 13(3).&358~366 综述了含烯基取代基的茂钛族络合物的合成,取代基上双键的化学反应,以及在α-烯烃催化聚合上的最新进展.表2参45 国家自然科学基金(29871010)资助 O643 01050233 氧化态Co/γ-Al2O3催化剂的结构与反应性能研究:Ⅱ.钴物种微观结构的XAFS表征=Studies on the Structures and Catalytic Properties of Oxidized Co/γ-Al2O3 Catalysts:Ⅱ.XAFS Characterizations of the Micro-Structures of Co Species[刊, 中]/孟明(中国科学技术大学),林培琰…∥分子催化.&2000, 14(3).&161~165 采用X-射线吸收近边结构与扩展X-射线吸收精细结构技术,对用不同原料盐和不同焙烧温度制得的Co/γ-Al2O3催化剂中钴的微观结构进行了详细的表征.图5表1参8 国家自然科学基金(29973037)资助 O643 01050234 CuCl/γ-Al2O3上NO脱除过程研究=Reaction Mechanism of NO Conversion over CuCl/γ-Al2O3[刊, 中]/朱月香(北京大学),尉继英…∥分子催化.&2000, 14(3).&166~170 设计了一系列的对比实验,利用XRD、XPS、TPR、EXAFS等技术,系统研究了CuCl/γ-Al2O3上的NO脱除反应过程.图4表1参8 国家自然科学基金(29733080)资助 O643 01050235 以Au(PPh3)(NO3)为前体的Au/NiO催化剂的制备及其对CO的催化氧化=Preparation and Catalytic Performance of Au/NiO Catalyst Derived from Au(PPh3)(NO3) for CO Oxidation[刊, 中]/邹旭华(烟台大学),齐世学…∥分子催化.&2000, 14(3).&171~174 采用有机金属配合物固载法,将金的有机配合物Au(PPh3)(NO3)沉积于刚制备出的Ni(OH)2沉淀上.结果表明,以K2CO3作为制备Ni(OH)2的沉淀剂,金担载量为3%(质量分数)在焙烧温度为300℃的条件下,制备出的负载型金催化剂Au/NiO对CO的低温氧化有很高的催化活性.图2表3参15 国家自然科学基金(29873041)资助 O643 01050236 CexZr1-xO2复合氧化物负载PdO催化剂的CO和CH4氧化性能研究=CO and Methane Oxidation over CexZr1-xO2 Mixed Oxide Supported PdO Catalysts[刊, 中]/马磊(浙江大学),韩立峰…∥分子催化.&2000, 14(3).&175~178 浙江省自然科学基金资助 O643 01050237 溶胶-凝胶法镍基催化剂的研究&&Ti/Si原子比对NiO-TiO2-SiO2结构和苯加氢性能的影响=Study of the Nickel Catalysts Prepared by Sol-Gel Method&&The Effects of Si/Ti Atomic Ratios on the Structure and Catalytic Performance for Benzene Hydrogenation of NiO/TiO2-SiO2[刊, 中]/朱毅青(江苏石油化工学院),林西平…∥分子催化.&2000, 14(3).&184~190 中石化集团公司资助课题 O643 01050238 (NH4)15[La(PMo9V2O39)2]*6H2O杂多配合物对苯酚羟化的催化作用=Catalytic Activity of (NH4)15[La(PMo9V2O39)2]*6H2O Heteropoly Complex in Phenol Hydroxylation with Hydrogen Peroxide[刊, 中]/林深(福建师范大学),郑瑛…∥分子催化.&2000, 14(3).&191~194 福建省科委资助项目 O643 01050239 Co改性Mo/HZSM-5催化剂上甲烷无氧芳构化反应研究=Methane Dehydro-Aromatization over Cobalt Modified Mo/HZSM-5 Catalysts in the Absence of Oxygen[刊, 中]/田丙伦(中科院大连化学物理所),刘红梅…∥分子催化.&2000, 14(3).&200~204 国家重点基础研究发展规划项目 O643 01050240 甲醇催化氧化重整反应制氢的研究=Hydrogen Production by Catalytic Oxidation and Reforming of Methanol[刊, 中]/陈兵(华南理工大学),董新法…∥分子催化.&2000, 14(3).&205~208 广东省高教厅自然科学基金资助 O643 01050241 TiO2催化Cr(Ⅵ)-氯代苯酚共存体系中Cr(Ⅵ)的光致还原=Photo-Induced Cr(Ⅵ) Reduction in Cr(Ⅵ)-4CP Coexist Pollution System in the Presence of TiO2 Photocatalyst[刊, 中]/付宏祥(中科院兰州化学物理所),吕功煊…∥分子催化.&2000, 14(3).&214~218 中科院重大项目资助 O643 01050242 三磺化三苯基膦(TPPTS)制备方法的改进=Improvement of Synthesis Method of TPPTS[刊, 中]/张敬畅(北京化工大学),曹维良…∥分子催化.&2000, 14(3).&223~226 国家"九五”科技攻关项目 O644 01050243 预处理对TiO2表面超亲水性的影响=Effect of Pretreatment on Superhydrophilicity of TiO2 Films[刊, 中]/管自生(中科院化学所),马颖∥感光科学与光化学.&2000, 18(3).&204~207 在高温度环境下,应用紫外光辐射对溶胶-凝胶TiO2薄膜预处理,经过预处理的薄膜烧结后具有快速光致高度亲水特性和良好的光催化活性.超亲水的薄膜能够吸附大量的酸性品红,在光照下薄膜将吸附的酸性品红逐渐降解掉.图3参6 国家自然科学基金(59932040)重点资助 O644 01050244 荧光探针在测定N-异丙基丙烯酰胺共聚物最低临界溶液温度(LCST)时的扩散过程=The Diffusion Process of Fluorescence Probe in Measurement of LCST of Poly(N-Isopropylacrylamide-co-Acrylamide) Aqueous Solution[刊, 中]/李俊(中科院感光化学所),史向阳∥感光科学与光化学.&2000, 18(3).&208~213 合成了多种不同配比的N-异丙基丙烯酰胺(NIPAM)与丙烯酰胺(AM)的共聚物.研究了共聚物溶液在温度变化过程中发生的线团-胶粒转变,及荧光探针分子扩散进入疏水胶粒的动力学过程.图3表2参9 国家自然科学基金(29733100)资助 O644 01050245 蒽醌冠醚铕离子络合物分子内能量转移=Intramolecular Energy Transfer in Anthraquione Crown Ether-Eu3+ Complex[刊, 中]/江华(中科院感光化学所),许慧君∥感光科学与光化学.&2000, 18(3).&223~228 研究结果表明,选择性激发铕离子络合物中的蒽醌冠醚能发生分子内能量转移,观察到铕离子的发光.荧光衰减测试表明,由于冠醚的包络作用使得铕离子络合物的荧光寿命较未络合铕离子的寿命有所延长.图5表1参10 国家自然科学基金(29733100)资助 O644 01050246 有机染料光褪色机理及主要原因=The Mechanism and Main Reasons of Photofading of Organic Dyes[刊, 中]/于新瑞(大连理工大学),张淑芬∥感光科学与光化学.&2000, 18(3).&243~253 综述了有机染料光褪色机理的主要研究方法以及现有研究结论.对光氧化和光还原过程、影响因素、典型反应步聚、研究手段进行了系统的阐述,同时也对通过染料分子结构设计合成、通过添加剂的使用提高染料光牢度的方法进行了介绍.图4表3参29 国家自然科学基金重点基金(29836150)资助 O644 01050247 荧光分子开关的研究进展=The Progress of the Research on Fluorescent Molecular Switches[刊, 中]/甘家安(华东理工大学),陈孔常∥感光科学与光化学.&2000, 18(3).&254~262 根据开关动作完成的方式对近年来研究的各类荧光分子开关进行了简要的归类总结,并介绍了一些具有特殊功能的荧光分子开关器件.图8参33 国家自然科学基金(29836150)资助 O644 01050248 半花菁衍生物LB膜的光致荧光特性研究=Photoluminescence Characteristics of Hemicyanine Derivatives in Langmuir Blodgett Multilayers[刊, 中]/王文军(复旦大学),陆兴泽…∥物理化学学报.&2000, 16(6).&496~500 通过改变半花菁的亲水基团与硫水基团而得到了四种半花菁衍生物,利用稳态和时间分辨荧光研究了不同亲水基团与疏水基团对半花菁衍生物光学特性的影响.图1表3参7 国家自然科学基金重点基金(19834030)资助 O644 01050249 N-萘甲基多乙撑多胺类荧光化学敏感器=Fluorescence Chemical Sensor of Naphthylmethyl Polyethylenepolyamine[刊, 中]/梅明华(中科院感光化学所),吴世康∥物理化学学报.&2000, 16(6).&559~562 合成了一类带有萘甲基的多乙撑多胺化合物,对其在不同溶剂中作为FCS检测锌离子时的荧光光谱变化进行了研究.结果表明,两种不同锌盐化合物与配体相互作用时,其所带阴离子对络合物的组成和方式有很大的影响.图2表1参6 国家自然科学基金(29733100)资助 O644 01050250 三聚氰胺甲醛树脂的光学性质=Optical Properties of Melamine Formaldehyde Resin[刊, 中]/刘海波(复旦大学),侯占佳…∥物理化学学报.&2000, 16(6).&563~567 对三聚氰胺甲醛树脂的合成过程、波导制备条件及利用三聚氰胺甲醛树脂作为掺杂基质的非线性光学性质进行了研究.实验结果表明,三聚氰胺甲醛树脂是一种极具有应用前景的光学材料.图3参14 国家自然科学基金(69708005,69808001)资助 O644 01050251 紫菜两个光系统间激发能分配研究对光合进化的启示[刊, 中]/潘洁(中科院化学所),施定基…∥科学通报.&2000, 45(12).&1276~1279 选择两个不同发育阶段(孢子体和配子体)的条斑紫菜作为研究对象.对过多激发能在两个光系统间的分配进行了比较研究.图2参13 国家自然科学基金(39890390,29733100)资助 O644 01050252 非线性光学配合物的化学研究[刊, 中]/左景林(南京大学),游效曾∥科学通报.&2000, 45(14).&1457~1464 从化学角度出发,在分子水平上研究和探索新型分子基非线性光学材料是一个新的研究领域.总结了近年来在新型二阶、三阶极化率和光限制等非线性光学配合物的化学研究方面所取得的进展.图6表2参46 国家自然科学基金(29631040)资助 O644 01050253 螺旋共轭化合物1′,3′,3′-三甲基-6-羟基螺旋[2H-1-苯并吡喃-2,2′-二氢吲哚]的结构、光谱、非线性光学性质和光异构化过程的理论研究=Theoretical Study of the Structures, Spectra, Nonlinear Second-Order Optical Properties and Photoisomerization Process of the Spiroconjugated Compound 1′,3′,3′-Trimethyl-6-Hydroxyspiro[2H-1-Benzopyran-2,2′-Indoline][刊, 中]/孙秀云(吉林大学),封继康…∥高等学校化学学报.&2000, 21(7).&1080~1085 用AM1和ZINDO方法研究了螺旋共轭化合物1′,3′,3′-三甲基-6-羟基螺旋[2H-1-苯并吡喃-2,2′-二氢吲哚](HBPS)及其光导构化产物的结构和光谱性质,从理论上研究了HBPS的光异构化反应过程,并在此基础上,用自编的完全态求和公式(SOS)程序计算了非线性光学系数.图4表7参17 国家自然科学基金(29873016)资助 O644 01050254 Af型自由基均聚反应的固化理论(Ⅲ)&&高分子凝胶网络缺陷=The Curing Theory of Af Type Free Radical Homopolymerization(Ⅲ)&&The Defects of Polymer Gel Network[刊, 中]/王海军(河北大学),赵敏…∥高等学校化学学报.&2000, 21(7).&1138~1141 应用高分子反应统计理论,分析了高分子网络的形成过程,讨论了Af型自由基均聚反应凝胶网络中的缺陷&&悬吊环的数目及其形成几率.图4参22 国家自然科学基金(29673018)资助 O646 01050255 微过氧化物酶-11修饰电极对O2和H2O2的电催化还原=Electrocatalytic Reduction of O2 and H2O2 at the Glass Carbon Electrode Modified with Microperoxidase-11[刊, 中]/杨辉(南京师范大学),黄志忠…∥物理化学学报.&2000, 16(6).&527~532 运用电化学循环伏安法和旋转圆盘电极技术研究了O2和H2O2在Nafion膜固定的微过氧化物酶-11修饰的玻碳电极上的电化学还原.图6参16 国家自然科学基金资助 O646 01050256 电沉积Co-Cu颗粒膜的巨磁电阻效应=Giant Magnetoresistance in Electro-Deposited Co-Cu Granular Film[刊, 中]/李浩华(兰州大学),黎超…∥物理化学学报.&2000, 16(6).&573~576 用电化学沉积法制备了Co-Cu纳米颗粒膜,并对这种膜的结构、磁性、巨磁电阻效应作了较详细的研究.图6参7 国家自然科学基金资助 O646 01050257 磷酸溶液中铝恒压阳极氧化的研究=Investigation of Aluminum Anodizing in Phosphoric Acid Solution at Constant Voltage[刊, 中]/王为(天津大学),郭鹤桐…∥天津大学学报.&2000, 33(3).&341~343 结果表明,随着电解电压的升高,形成的氧化铝多孔膜的阻挡层增厚,多孔层的孔径和胞径均增加,其原因与离子迁移等密切相关.图6参6 国家自然科学基金(69601006)资助 O646 01050258 二次微分简易示波伏安法测定痕量镍=Determination of Trace Nickel by Second-Order Differential Simple Oscillographic Voltammetry[刊, 中]/傅业伟(西北大学),高敏…∥应用化学.&2000, 17(3).&296~299 国家自然科学基金(29775018)资助 O646 01050259 Ml(NiCuAlZn)5储氢合金粉末的包覆处理=Encapsulation of Ml(NiCuAlZn)5 Hydrogen Storage Alloy Powder[刊, 中]/王一菁(南开大学),赵东…∥应用化学.&2000, 17(3).&310~312 国家"八六三”计划资助项目 O646 01050260 和厚朴酚电化学还原机理的研究=Theoretical Study on the Mechanism of Electrochemical Reductions Reaction of Honokiol[刊, 中]/孙成科(曲靖师范高等专科学校),龚思源…∥高等学校化学学报.&2000, 21(6).&912~917 用量子化学AM1、PM3方法研究了和厚朴酚分子的电化学还原反应机理.结果表明,和厚朴酚分子电还原的基团为两个烯丙基的双键,其中邻位烯丙基优先被还原,对位次之,整个还原反应中和厚朴酚得到4e和4H+,使两个烯丙基饱和,计算结果较好地说明了实验事实.图2表7参12 国家自然科学基金(29773007)资助 O646 01050261 Fourier自去卷积示波计时电位法的研究=Oscillographic Chronopotentiometry with Fourier Self-Deconvolution[刊, 中]/郑建斌(西北大学),张红权…∥高等学校化学学报.&2000, 21(7).&1037~1039 国家自然科学基金(29775018)资助 O646 01050262 用规整膜板对砷化镓的三维微结构图形加工刻蚀=Three-Dimensional Microfabrication on GaAs Using a Regular Patterns Mold[刊, 中]/董海苟(厦门大学),孙建军…∥电化学.&2000, 6(3).&253~257 以微齿轮图形结构作为规整模板.用约束刻蚀剂层技术对GaAs样品表面进行了加工刻蚀.在有捕捉剂H3AsO3存在的情况下,规则微齿轮图形能够很好地在样品表面复制.图5参6 国家自然科学基金重点项目(29833070)资助 O646 01050263 混凝土中钢筋的腐蚀行为研究=Corrosion Behavior of Reinforcing Steel in Concrete[刊, 中]/林荣归(厦门大学),胡融刚…∥电化学.&2000, 6(3).&305~310 钢筋在混凝土中受到高碱性环境的保护,耐蚀性好,但随着介质pH的降低、Cl-含量的上升,钢筋腐蚀电流升高;动电位阳极极化曲线的测试表明,钢筋的维钝电流增大,击穿电位负移,混凝土中钢筋的耐蚀性下降.图4表1参6 国家自然科学基金(59871043)资助 O647 01050264 天冬氨酸在Cu(001)表面吸附的扫描隧道显微镜研究=Adsorption of Aspartic Acid on Cu(001) Studied by Scanning Tunneling Microscopy[刊, 中]/王浩(北京大学),赵学应…∥物理学报.&2000, 49(7).&1316~1320 国家自然科学基金(19634010)资助 O647 01050265 共聚高分子吸附的Monte Carlo模拟=Monta Carlo Simulation of Adsorption of Diblock Copolymer at Solid-Liquid Interface[刊, 中]/陈霆(华东理工大学),刘洪来…∥化工学报.&2000, 51(4).&512~518 用Monte Carlo方法对选择性溶剂中两嵌段共聚高分子在固液界面的吸附进行了模拟,获得了吸附等温线以及吸附层厚度、链附着率、表面覆盖率、链节浓度分布等表征吸附层结构的信息,同时模拟获得了固液界面区吸附构型大小及分布等表征高分子构型的微观信息.图12表1参10 国家自然科学基金(29736170)资助 O647 01050266 无规共聚高分子溶液相平衡的Monte Carlo模拟=Monte Carlo Simulations of Phase Equilibria of Random Copolymer Solutions[刊, 中]/陈霆(华东理工大学),刘洪来…∥化工学报.&2000, 51(4).&552~554 用构型偏倚蒸发Monte Carlo方法模拟研究了密堆积格子模型上A、B无规共聚高分子的相平衡问题,无规共聚高分子中链节A、B以不同的相互作用能来区别.模拟获得了链长直至200个链节的无规共聚高分子系统相平衡数据,同时计算获得了不同链长固定组成下无规共聚高分子系统相应的临界点.图2表1参12 国爱自然科学基金(29736170)资助 O648 01050267 Triton X-100/正癸醇/水层状液晶制备泡囊=Preparation of Vesicles from Lamellar Liquid Crystal in Triton X-100/n-C10H21OH/H2O System[刊, 中]/丁元华(扬州大学),刘天晴…∥物理化学学报.&2000, 16(6).&481~486 以Triton X-100/n-C10H21OH/H2O体系生成的层状液晶为介质制备泡囊,所得泡囊分布比较均匀,囊径在0.2~0.5 μm之间.研究了层状液晶组成、pH、超声振荡时间等因素对所制泡囊的电位及微极性的影响.图6表2参16 国家自然科学基金(29673035)资助 O648 01050268 表面波技术研究TBP对C12E8表面流变性质的影响=Influence of TBP on the Surface Rheological Properties of C12E8 Studied by Surface Wave Method[刊, 中]/韩国彬(厦门大学),吴金添…∥物理化学学报.&2000, 16(6).&507~511 利用表面波技术研究消泡剂TBP对起泡剂C12E8表面流变性质的影响,阐述泡沫的排液过程中液膜变形所产生的表面张力梯度修复机理以及液膜强度与表面膨胀模量、表面膨胀弹性和表面膨胀粘度的关系,并且探讨了消泡剂TBP的消泡机理.图4参6 国家自然科学基金(29973033)资助 O648 01050269 制备宽温区O/W微乳的新方法=Novel Method to Prepare O/W Microemulsions within a Wide Temperature Range[刊, 英]/梁文平(中科院化学所),Tharwat F Tadros∥物理化学学报.&2000, 16(6).&538~542 通过把一个带有羧基的离子表面活性剂镶嵌在微乳界面的单分子层中,在低pH值时,形成水包油微乳,然后用氢氧化钠中和使其表面离子化而形成一个较厚的双电层,从而得到的宽温区(0-90℃)水包油微乳.研究了油相浓度、pH以及微乳液滴的大小对体系的浊点的影响.图5参12 国家自然科学基金资助 O65 01050270 Triton X-100与牛血清白蛋白的相互作用=The Interaction between Triton X-100 and Bovine Serum Albumin[刊, 中]/魏晓芳(中科院化工冶金所),刘会洲∥分析化学.&2000, 28(6).&699~701 国家自然科学基金重点项目资助 O65 01050271 球形铜离子模板缩聚物的制备及其选择吸附性能=The Preparation of Globular Copper(Ⅱ) Template Condensation Polymer and Its Behavior of the Selective Adsorption[刊, 中]/王旭东(南开大学),何锡文…∥分析化学.&2000, 28(7).&805~809 以苯酚、甲醛、四乙烯五胺为反应单体,铜离子为模板,反相悬浮聚合制备出球形离子模板缩聚物.该模板缩聚物对铜离子的吸附性能显著优于相应的非模板缩聚物.图6参3 国家自然科学基金(29775011)资助 O65 01050272 杯芳烃银离子敏感场效应晶体管传感器=Silver Ion-Sensitive Field-Effect Transistor Based on Calixarene[刊, 中]/陈朗星(南开大学),牛文成…∥分析化学.&2000, 28(7).&815~819 报道了硫醚取代的杯[4]芳烃化合物的合成,以此化合物为敏感材料,研制了聚氯乙烯膜的银离子敏感场效应晶体管(Ag+-ISFET)传感器.Ag+-ISFET传感器对银离子表现出优良的能斯特响应,该传感器对碱金属、碱土金属及过渡金属离子有极高的选择性.图5表1参13 国家自然科学基金(29975014)资助 O65 01050273 电极扩散层内物质浓度及分布研究方法进展=Development of Research Method of Concentration Observation and Distribution in Electrode Diffusion Layer[刊, 中]/杨玉书(重庆大学),夏之宁…∥分析化学.&2000, 28(7).&897~903 评述了测试电极扩散层内物质浓度及分布的各种方法,分别从方法原理、实验装置、影响因素及其应用等方面加以论述,评价了各种方法的特点,并对发展方向进行了展望.参52 国家自然科学基金(29775035)资助 O657 01050274 甲烷氧化偶联Na-W-Mn/SiO2催化剂的喇曼光谱=Raman Spectroscopy Characterization of Na-W-Mn/SiO2 Catalyst for Oxidative Coupling of Methane[刊, 中]/陈宏善(中科院兰州化学物理所),牛建中…∥物理化学学报.&2000, 16(6).&543~546 研究了A16061/SiCp复合材料表面双层稀土转化膜的微观结构以及化学组成,并对稀土转化膜对抗腐蚀性能进行了评估.结果表明,稀土转化膜能显著提高耐蚀性.图2表3参10 国家自然科学基金资助 O657 01050275 12-钼磷酸-葡聚糖包合物的研究=Study on the Inclusion Compound of 12-Molybdenum Phosphoric Acid with Dextran[刊, 中]/程贤C026(福建师范大学),苏英草…∥物理化学学报.&2000, 16(7).&658~662 福建省教委基金资助 O657 01050276 O/W微乳液中制备甲基丙烯甲酯-苯乙烯共聚物超细颗粒=Preparation of Methyl Methacrylate and Styrene Copolymer Ultrafine Particles in the Oil-in-Water Microemulsions[刊, 中]/钱君律(同济大学),甘礼华…∥同济大学学报(自然科学版).&2000, 28(3).&320~323 在甲基丙烯酸甲酯(MMA)-苯乙烯-环己烷/十六烷基三甲基溴化铵/水体系的O/W微乳液中,制备了粒径约58 nm球状甲基丙烯酸甲酯-苯乙烯共聚物超细颗粒.研究了影响粒子形态和大小的因素.图4表1参12 国家自然科学基金(29673030)资助 O657 01050277 基于小波神经网络的新型算法用于化学信号处理=A Novel Algorithm Based on the Wavelet Neural Network for Processing Chemical Signals[刊, 中]/蔡文生(中国科技大学),于芳…∥高等学校化学学报.&2000, 21(6).&855~859 基于紧支集正交小波神经网络的构造思想,用具有紧支集的B-样条函数的伸缩和平移替代小波函数,提出了一种新型算法,并将其应用于化学信号的处理,实现了信号的压缩和滤噪,与自适应小波神经网络相比,学习速度得到了大幅度的提高.图4表2参9 国家自然科学基金(29775001)资助 O657 01050278 改进溶胶-凝胶法固定酶结构剖析及在苯酚光化学传感器中的应用=The Microstructure Analysis of Enzymes Immobilized by Sol-Gel Method and Its Application in Phenol Optical Chemical Sensor[刊, 中]/李军(湖南大学),王柯敏…∥高等学校化学学报.&2000, 21(7).&1018~1022 结果表明,酶固定于溶胶-凝胶中后,与在溶液中一样,呈均匀分布且不易流失.此敏感膜可用于制备基于化学发光强度减弱的苯酚光化学传感器;用竞争反应的原理讨论了响应机理.图3表1参20 国家自然科学基金(29675005)及国家杰出青年基金(29825110)资助 O657 01050279 一种用于电热蒸发-原子光谱的微型化固相萃取技术=A Miniaturization Solid-Phase Extraction Technique Designed for Electrothermal Vaporization-Atomic Emission Spectrometry Determination[刊, 中]/熊宏春(武汉大学),胡斌…∥高等学校化学学报.&2000, 21(7).&1035~1036 国家自然科学基金(29875022)资助 O657 01050280 多环芳烃芴、苊的无保护流体室温磷光性质研究=Studies on Non-Protected Fluid Room Temperature Phosphorescence of Polycyclic Aromatic Hydrocarbon of Fluoren and Acenaphthene[刊, 中]/李隆弟(清华大学),牟兰…∥高等学校化学学报.&2000, 21(7).&1040~1042 国家自然科学基金(29775013)资助 O657 01050281 高效液相色谱/大气压化学电离质谱快速分析水中痕量有机磷农药=Rapid Analysis of Trace Organophosphorous Pesticides in Water by High Performance Liquid Chromatography/Atmospheric Pressure Chemical Ionization Mass Spectrometry[刊, 中]/潘元海(中科院生态环境研究中心),金军…∥分析化学.&2000, 28(6).&661~671 用反相液谱短柱实现了6种有机磷农药(乙酰甲胺磷,甲基对硫磷、杀螟硫磷、喹硫磷、二嗪农、辛硫磷)的高效液相色谱/大气压化学电离质谱(HPLC/APCIMS)快速分析.此技术可以很好地实现水中痕量有机磷农药的测定,一次联机分析仅需10 min.图3表2参11 国家自然科学基金(29977023)资助 O657 01050282 氧氟沙星对映体的同步-导数荧光光谱法识别与测定=Recognition and Determination of Ofloxacin Enantiomers by Synchronization-Derivative Fluorimetry[刊, 中]/弓巧娟(山西大学),晋卫军…∥分析化学.&2000, 28(6).&672~677 控制pH=3,首次通过同步一阶导数荧光光谱技术,有效地识别和分辨氧氟沙星的R和S对映体,同时有效地消除尿样背景的干扰.据此建立了同时识别与测定两种旋光体的同步-导数荧光光谱法.图5表2参9 国家自然科学基金(29875016)资助 O657 01050283 一种新的重原子微扰剂氯代叔丁烷在亚硫酸钠化学除氧环糊精诱导室温磷光法中的应用研究=A Study of t-Butyl Chloride as Heavy Atom Perturber in Chemical Deoxygenation-Cyclodextrin Induced Room Temperature Phosphorimetry[刊, 中]/张淑珍(山西大学),魏雁声…∥分析化学.&2000, 28(6).&678~681 以氯代叔丁烷作重原子微扰剂采用亚硫酸钠化学除氧技术建立了菲、7,8-苯并喹啉、2-溴代萘在环糊精介质中的室温磷光分析法.图4表2参5 国家自然科学基金(29575204)资助 O657 01050284 小牛胸腺脱氧核糖核酸诱导中性红聚集的机理及其影响因素=The Aggregation of Neutral Red Encouraged by Deoxyribonucleic Acids and Its Depending Factors[刊, 中]/黄新华(西南师范大学),李原芳…∥分析化学.&2000, 28(6).&682~686 在pH7.6~7.8和低离子强度条件下,中性红与小牛脱氧核糖核酸(ctDNA)作用产生以535 nm为特征的共振光散射增强(ERLS)光谱.机理研究表明,这种ERLS是由于DNA诱导中性红的聚集所致.图6表1参11 国家自然科学基金(29875019)资助 O657 01050285 蛋白质样品的非竞争性毛细管电泳免疫分析激光诱导荧光检测=Noncompetitive Capillary Electrophoresis Based Immunoassay for Proteins with Laser Induced Fluorescence Detection[刊, 中]/王清刚(清华大学),罗国安…∥分析化学.&2000, 28(6).&687~691 国家自然科学基金重点资助 O657 01050286 亲和毛细管电泳测定孕酮与其单克隆抗体的结合常数=Determination of the Binding Constant between Progesterone and Its Monoclonal Antibody Using Affinity Capillary Electrophoresis[刊, 中]/王清刚(清华大学),王义明…∥分析化学.&2000, 28(6).&731~734 采用亲和毛细管电泳的配体分离模式,以激光诱导荧光作为检测手段,测定了荧光素标记的孕酮与孕酮单克隆抗体之间的结合常数,并研究了温育时间、电泳条件等因素对测定的影响.图3参5 国家自然科学基金重点资助 O657 01050287 钌(Ⅱ)-联吡啶-铈(Ⅳ)-戊二醛化学发光体系及其应用=Chemiluminescence System of Ru(bpy)2+3-Ce(Ⅳ)-Glutaraldehyde and Its Application[刊, 中]/韩鹤友(武汉大学),何治柯…∥分析化学.&2000, 28(6).&738~740 基于在硫酸介质中戊二醛增强铈(Ⅳ)氧化钌(Ⅱ)-联吡啶的化学发光强度.在优化后的条件下,方法的线性范围和检测限分别为2.5×10-6~2.5×10-3 mol/L和3.1×10-7 mol/L戊二醛.图1表1参6 国家自然科学基金(29605001)资助 O657 01050288 毛细管区带电泳法测定甲氧苄胺嘧啶和磺胺甲基异C023唑的离解常数及其在复方新诺明中的含量=Determination of Dissociation Constants of Trimethoprim and Sulfamethoxazole and Their concentrations in Co-Trimoxazole Tablets by Capillary Zone Electrophoresis[刊, 中]/李前锋(兰州大学),张红医…∥分析化学.&2000, 28(7).&793~797 国家自然科学基金(29475194和29675007)资助 O657 01050289 联用色谱数据的半自动解析法=Semiautomatic Deconvolution of Hyphenated Chromatographic Data[刊, 中]/甘峰(湖南大学),李晓宁…∥分析化学.&2000, 28(7).&833~836 采用正交投影法获得初始迭代光谱,继采用非负最小二乘法和常规最小二乘法进行交替迭代,最终获得纯光谱和纯色谱向量.图2参15 国家自然科学基金(29875007)资助 O657 01050290 陈皮挥发油的气相色谱/质谱分析=Determination of the Volatile Oil of Pericarpium Citri Reticulatae with Gas Chromatography/Mass Spectrometry[刊, 中]/龚范(湖南大学),梁逸曾…∥分析化学.&2000, 28(7).&860~864 用GC/MS分析复方制剂平胃散中的一种单味药材陈皮的挥发油化学成分及其相对含量.分离出53个组分,其中鉴定了34个组分,约占其挥发油总量的96.08%.图5表1参7 国家自然科学基金(29875007)资助 657 01050291 人工神经网络法鉴别红外光谱=Artificial Neural Network for the Identification of Infrared Spectra[刊, 中]/李燕(南京理工大学),王俊德…∥光谱学与光谱分析.&2000, 20(4).&477~479 将反向传播人工神经网络用于FTIR,鉴别未知化合物.结果表明,当训练集样本不含噪声时,纯光谱的预测结果很好.而当训练集样本有少量噪声干扰时,预测结果随预测集样本的不同,而得到了不同的改善.图3参6 国家自然科学基金资助 O657 01050292 苯丙氨酸桥联金属双卟啉的诱导圆二色光谱研究=The Study of Induced Circular Dichroism of Phenylalanine Bridged Metal Bis-Porphyrin[刊, 中]/刘海洋(华南理工大学),黄锦汪…∥光谱学与光谱分析.&2000, 20(4).&495~497 报道了邻位和对位桥联苯丙氨酸锌双卟啉的合成,考查了双卟啉的分子结构对诱导圆二色性的影响.结果表明,两个卟啉环之间的π-π堆积和手性激子偶合作用是影响此类双卟啉圆二色光谱的主要因素.图3参16 国家自然科学基金(29771034)资助 O657 01050293 砷和汞的顺序注射-蒸气发生原子吸收光谱测定=Sequential Injection Vapor Generation Atomic Absorption Spectrometric Determination of Mercury and Arsenic[刊, 中]/马泓冰(东北大学),徐淑坤…∥光谱学与光谱分析.&2000, 20(4).&529~532 建立了砷和汞的顺序注射-蒸气发生原子吸收光谱测定方法.在流动注射蒸气发生原子吸收光谱测定方法的基础上,采用汇流技术,通过两个微量注射泵和一个多位选择阀的计算机程控操作,实现待测组分与硼氢化钠间的强氧化还原反应及其气-液分离过程.图3表4参4 国家自然科学基金资助 O657 01050294 氢化物的气相富集及其在超痕量分析中的应用=The Gaseous Phase Enrichment Techniques in Hydride Generation (Review)[刊, 中]/郭旭明(厦门大学),黄本立…∥光谱学与光谱分析.&2000, 20(4).&533~536 从富集原理及其在光谱超痕量分析的应用方面分别对这几种氢化物发生后的气相富集技术进行了较详细地综述.这些气相富集方法包括液氮冷却捕集技术、气球收集技术、石墨炉原位捕集技术、吸收液吸收技术及固体吸附技术等.参63 国家自然科学基金资助 O657 01050295 pH诱导牛血清白蛋白芳香氨基酸残基微环境变化的光谱分析=Spectral Study of the Microenviroment Change of Aromatic Amino-Acid Residues in BSA Induced by pH[刊, 中]/魏晓芳(中科院化工冶金所),刘会洲…∥光谱学与光谱分析.&2000, 20(4).&556~559 用荧光光谱和紫外吸收光谱研究了pH=2.3~11.3范围内牛血清白蛋白芳香氨基酸残基微环境的变化,以此推断蛋白质构象的变化,并讨论蛋白质表面疏水性变化的趋势.图4表1参8 国家自然科学基金重点基金资助 O657 01050296 传感器几何结构对近红外组织氧合检测仪灵敏度的影响=The Influence of Probe Geometry on the Sensitivity of Tissue Oximeter Using Near Infra-Red Spectroscopy[刊, 中]/王峰(清华大学),丁海曙…∥光谱学与光谱分析.&2000, 20(4).&585~588 利用蒙特卡罗仿真方法对光在多层生物组织模型中的平均穿透深度、光子平均飞行距离和空间灵敏度分布进行了仿真,结果表明,传感器几何结构,即光源与光检测器之间的距离是影响灵敏度的重要因素,适当增加这一距离有助于深层组织生化信息的提取和测量灵敏度的提高,但是它又受到信噪比降低的限制.图8参3 国家自然科学基金资助 O657 01050297 精密气动液压伺服系统用于傅里叶变换光谱仪光谱测量=Spectral Measuring of Fourier Transform Spectrometer Using Pneumatic Hydraulic Servo System[刊, 中]/李志刚(中科院长春光学精密机械所),王淑荣…∥光谱学与光谱分析.&2000, 20(4).&589~591 讨论了傅里叶变换光谱仪动镜稳定平移的重要性,研制了以高压无氧氮气为动力源的精密气动液压系统用于推进在研傅里叶变换光谱仪"猫眼”动镜系统,并在此基础上测量了ZYGO干涉仪光源光谱图.图4参5 国家自然科学基金资助 O658 01050298 超临界流体色谱法分离手性化合物的进展=Advances in Chiral Separations by Supercritical Fluid Chromatography[刊, 中]/任其龙(浙江大学),苏宝根…∥分析化学.&2000, 28(6).&772~776 国家自然科学基金(29776040)资助 O658 01050299 长江口水体混合过程中溶解态稀土元素分布特征[刊, 中]/王中良(中科院地球化学所),刘丛强∥科学通报.&2000, 45(12).&1322~1326 采用液-液萃取与反萃取分离富集方法和ICP-MS测试技术,对长江河口南支盐度0.15~19 mg/g表层水体中溶解态稀土元素的浓度进行了测定.图2表1参17 国家杰出青年科学基金(49625304)资助 O658 01050300 分子烙印手性固定相分离过程热力学研究=Thermodynamic Study on Separation of Molecular Imprinting Chiral Stationary Phase[刊, 中]/王进防(中科院大连化学物理所),周良模…∥高等学校化学学报.&2000, 21(6).&930~933 结果表明,分子烙印手性固定相的分离过程为焓控制过程.随着温度的升高,样品的容量因子降低,手性选择因子α减小.样品与分子烙印固定相的作用力包括非特异作用力和特异作用力,只有特异作用力的差值才是手性分离的本质.表2参22 国家自然科学基金(29575212)资助 O658 01050301 十八烷基醚型高效液相反相色谱填料的制备=Synthesis and Characterization of Ether-Bond RP-Packing[刊, 中]/喻昕(中科院化学所),赵睿…∥高等学校化学学报.&2000, 21(7).&1043~1044 国家自然科学基金(29635010)资助