We performed a comparative study of digitally and conventionally acquired images in gastrointestinal examinations. Radiation dose and spatial resolution were determined in a water phantom. In 676 examinations with either conventional or digital imaging (system: Diagnost 76, DSI) the number of images and the duration of the fluoroscopy time were compared. 101 examinations with digital as well as conventional documentation were evaluated by using 5 criteria describing the diagnostic performance. The entrance dose of the DSI is 12% to 36% of the film/screen system and the spatial resolution of the DSI may be better than that of a film/screen system with a speed of 200. The fluoroscopy time shows no significant difference between DSI and the film/screen technique. In 2 of 4 examination modes significantly more images were produced by the DSI. With exception of the criterion of edge sharpness, DSI yields a significantly inferior assessment compared with the film/screen ...
Purpose: The determination of tumor volume in ocular tumors is very important for the planning and success of radiation therapy. This study uses an animal model to evaluate the accuracy of MR-based volumetry of ocular tumors. Materials and methods: In a total of 25 porcine eyes obtained from the slaughterhouse, ocular tumors were produced by injecting a mixture of hand creme and Gd-DTPA under ophthalmoscopic guidance. The injected volume varied between 0.05 ml and 2.7 ml. The eyes were examined with a 1.5 Tesla scanner and a 4 cm circular surface coil especially developed for ocular MRI. After data transfer to a separate workstation, volumetric analysis was carried out by three independent radiologists using semiautomated software. The determined volume was compared with the injected volume. Results: Of the 25 prepared porcine eyes, 23 were suitable for volumetric analysis. The injection of the mixture of hand creme and GD-DTPA produced two different types of tumors. ...
Two spreading experiments were performed at the FARO facility with prototypical core melts of a UO{sub 2}/ZrO{sub 2} weight percentage of 80/20. The objective was to obtain data on the spreading at flow rates of about 2 l/s of more than 100 kg prototypic high temperature oxide melt on a dry and wet stainless steel plate. For the second spreading test a shallow water layer of 10 mm was added on the substrate. Solutions for an isothermal spreading with a constant volume flux boundary condition in a sector with an angle {phi} are used to analyse the FARO L-32S experiment and to identify the source of discrepancies between the code results (THEMA, CORFLOW) and the experimental findings. The observed spreading behaviour of both FARO experiments can only be explained if an initial melt temperature below the liquidus temperature, i.e. about 120 K lower than the temperature measured by the UTS sensors is assumed. (orig.) [German] Zwei Ausbreitungsexperimente mit einer UO{sub 2}/ZrO{sub 2} ...
This richly illustrated toolbook and atlas contains information on all aspects of nmr diagnostic imaging of benign or malignant neoplasms of female and male mammary glands. It offers pinpointed guidance and insight for vocational training and continuing training of radiology assistants, students and medical radiologists. (orig./AJ) [German] Die MRT als hochaufloesendes und schaedigungsfreies Diagnostikum gewinnt gerade in der emotional stark besetzten Mammadiagnostik zunehmend an Bedeutung. Dennoch beherrschen nur wenige Zentren im deutschsprachigen Raum diese Technik, die - eine hohe Reproduzierbarkeit bei fehlender Belastung fuer die Patientin bietet, - invasive Karzinome bereits ab einer Groesse von 5 mm mit hoher Zuverlaessigkeit ausschliessen kann und - gerade bei widerspruechlichen Befunden zwischen klinischer Untersuchung, Roentgenmammographie und perkutaner Biopsie eine wesentliche Entscheidungshilfe bieten kann. Aus einem der ...
Based on the first part of this report the molybdenum loadings of the red mud were varied and the activity of the catalytic additives was tested in a batch autoclave with TJP VR. The 30% Molybdenum loading (sample Nr. 6) was found to be optimum. Further testing with two vacuum residues (TJP VR and ARH VR) and sample Nr. 6, indicates the influences of the process parameters for hydrogen pressures of 9-15 MPa, temperatures of 440-475 C and residence times of 0-60 min. Obviously 440 C, 12 MPa and a residence time of 30 min are best conditions for hydrocracking of both vacuum residues with sample Nr. 6. (orig.) [Deutsch] Beruhend auf dem ersten Teil des Berichtes wird der Belegungsgrad der Rotmasse mit Molybdaen variiert und die resultierenden katalytischen Zusaetze werden in einem Autoklaven mit TJR VR getestet. Ein Belegungsgrad mit 30% Molybdaen (Probe 6) scheint optimal zu sein. Mit diesem Zusatz werden die Einfluesse der Prozessparameter bei ...
An important opportunity for solving future traffic problems lies in a change of the connection existing between traffic growth and economic development. It could help bring about a cut in traffic intensity. This can be achieved by rationalizing transport processes, i.e. by enhancing the efficiency of traffic via improved organization and infrastructure. Rationalization means that a given traffic effort (distance in kilometres, time, route, energy) can yield a higher transport effect, or a certain transport effect can be attained with less traffic effort. Enhanced productivity permits more transport without more traffic-related and environmental nuisances. (orig.) [Deutsch] Ein wichtiger Weg zur Loesung der kuenftigen Verkehrsprobleme liegt in der Veraenderung des Zusammenhangs der zwischen Verkehrswachstum und Wirtschaftsentwicklung besteht. Damit koennte eine Senkung der Transportintensitaet erreicht werden. Ein Ansatz hierzu bietet die Rationalisierung der ...
Investigation of an HP-blade damage in 1996 and an MP-blade damage in 1007 at the mounting showed that fretting and creep fatigue had caused the damage. Break-down occurred when creep-related cracks developed between radial bridge to the upper blade tooth and weight relief boreholes. After disassembly of the HP-blades the lower blade tooth was found to be cracked after fretting (some cracks along the whole length of the tooth). The lower teeth of MP-bladedes showed merely superficial cracks (depth about 0.4mm). The massive cracks of the lower blade tooth were caused by instationary clearance changes combined with hard blade underground.(orig.) [German] Das Ergebnis der Untersuchung nach einem HD-Schaufelschaden 1996 sowie einem MD-Schaufelschaden 1997 an der Vierzackenfussbefestigung ergab Zeitstanderschoepfung und Fretting als auszuloesende Schadensmechanismen. Die Havarien wurden durch zeitstandbedingte Brueche zwischen ...
Sprayforming offers the possibility to produce a variety of preforms in a single step directly from the melt. Numerous processing parameters ensure high flexibility but require detailed knowledge concerning the microstructure of sprayformed material depending on chemical composition and processing parameters. Within the current study fundamental investigations using unalloyed and low alloy steel grades (C15, C105, 100Cr6) for sprayforming of plates and billets have been performed concerning the influence of chromium and carbon content and selected processing parameters. Sprayformed preforms revealed austenite grain sizes up to 500 {mu}m depending on the development of porosity. Different types of porosity have been detected which can be associated with incomplete densification due to high cooling rates, solidification shrinkage and entrapped nitrogen. Atomisation gas pressure and carbon content are parameters of primary importance. (Abstract Copyright [2003], Wiley Periodicals, Inc.) ...
To evaluate the usefulness of radiation therapy alternative to surgery for clinical N0-N1 non-small cell lung cancer (NSCLC). From 1976 through 1989, 116 patients with NSCLC without mediastinal involvement were treated with definitive radiation therapy alone at Gunma University Hospital. All patients were treated with once-daily standard fractionation using 10 MV X-rays. The total dose ranged from 60 Gy to 80 Gy. The actuarial 2- and 5-year survival rates of the entire group were 43% and 20%, respectively with a median survival time of 19 months. The survival of 76 patients with stage T2 tumors was significantly better than that of 28 patients with T3 tumors (mean survival time 21 versus 15.5 months; p<0.05). Sixty-two patients with tumors less than 5 cm in diameter had a 2-year progression rate of 20%, in comparison with 39% of 54 patients with tumors greater than 5 cm. The difference of survivals for these 2 groups was statistically significant. Twelve patients given a total dose ...
A singular stress field can occur at the edge of the joint plane in a thermally or mechanically loaded material compound. This stress field was calculated analytically and was compared with the results from the finite element method. If one of the two partners consists of ceramic material, unstable crack spread starting from faults in this strongly stressed area can lead to failure. In linear elastic material, the behaviour of a crack is clearly described by the stress intensity factors. These can be calculated for a known stress distribution in the uncracked structure by the method of the weight function. The corresponding weight functions for surface cracks parallel to the boundary surface were determined with the aid of suitable reference load cases. The effect of the position of the crack in the compound and the elastic constants of the compound are discussed. For examples, the stress intensity factors for cracks in a thermally stressed material compound were determined by the ...
The transversus perinei profundus muscle is a well known structure in found anatomical textbook. Fibres of this muscle are believed to form the so-called external urethral sphincter (musculus sphincter urethrae). Recently histomorphologic investigations have shown that there is no muscular connection between the musculus sphincter urethrae (external sphincter) and the muscle system of the pelvic floor. Furthermore, the external sphincter was found to be divided into parts: The transversely striated part (musculus sphincter urethrae transversostriatus) and the smooth part (musculus sphincter urethrae glaber). Similar to histomorphologic investigations, contrast-enhanced MR imaging has shown the musculus sphincter urethrae to be surrounded by fatty and connective tissue only. Neither in MRI nor in anatomical slices can any connection between the urethral sphincter and the muscle system of the pelvic floor be found. Thus, on the basis of the results presented in this work it is concluded ...
A model for combined mass and heat transfer during nonisothermal gas absorption in a two-phase gas- liquid bubbly medium with a high gas content and/or large times of gas-liquid contact is suggested. Diffusion and thermal interactions between bubbles is taken into account in the approximation of a cellular model of a bubbly medium whereby a bubbly medium is viewed as a periodic structure consisting of identical spherical cells with periodic boundary conditions at a cell boundary. Distribution of concentration of dissolved gas, temperature distribution in liquid and coefficients of mass and heat transfer during nonisothermal absorption of a soluble pure gas from a bubble by liquid are determined. In the limiting case of absorption without heat release the derived formulas recover the expressions for isothermal absorption. (orig.). With 1 fig., 1 tab. [Deutsch] Es wird ein Modell vorgestellt, das den kombinierten Waerme- und Stoffaustausch waehrend der nichtisothermen Gasabsorption in ...
Purpose: To assess the new method of 3-dimensional echocardiography in comparison to the 'gold standard' MRI as to its ability to calculate left ventricular volumes in patients with congenital heart disease. Materials and methods: Eighteen patients between the ages of 3.9 to 37.3 years (mean: 12.8{+-}9.7) with a geometrically abnormal left ventricle were examined using a 1.5 T scanner with a fast gradient-echo sequence (TR=14 ms, TE=2.6-2.9 ms, FOV=300-400 mm, flip angle=20 , matrix=128:256, slice thickness=5 mm, retrospective gating) in multislice-multiphase technique. Transthoracic 3D-echocardiography was performed with a 3.5 MHz transducer and a Tomtec {sup trademark} (Munich, Germany) system for 3D reconstruction. Results: Volume calculation was possible in all patients with 3D-echocardiography, but the muscle mass calculation only succeeded in 11 to 18 patients (61%) due to inadequate visualization of the entire myocardium. Comparing MRI and 3D-echocardiography, ...
Purpose: Measurement of the oscillating CSF flow in the spinal canal (SC) of healthy volunteers and in patients with post-traumatic syringomyelia (PTS) using an optimized MRI protocol as well as to determine whether stenosis induced velocity changes are detectable using MRI. Methods: In 68 healthy volunteers quantitative studies of CSF flow in the cervical, thoracic, and lumbar regions were performed. First, an optimized sequence was developed and tested in 19 volunteers using four different flow-encoding velocities (4, 8, 12, 16 cm/s). Secondly, the optimized sequence was employed in 49 volunteers to measure the different CSF patterns in the cervical, thoracic, and lumbar spinal canals (CSC, TSC, LSC). Part three of the study, in which patients with PTS are being examined is still underway. We measured the maximum velocity (cm/s), the pixel area (mm{sup 2}), and the stroke volume (ml/s). Using a flow model the velocities prior to and after compression with 5 different power levels ...
TRITEX was a pumped loop with Pb-15.8Li, fabricated from steel 1.4922. In contact with the molten eutectic were also molybdenum, vanadium and armco-iron. The loop was originally designed to investigate tritium extraction using solid getter metals. Over the years the goal changed to the study of metals, corrosion products and purification of the eutectic mixture. Therefore many modifications were done. The first part of this report describes TRITEX. All parts were enclosed in thermoboxes for a homogeneous temperature. One test section was in an argon glove box and could be opened during operation. Other special equipment`s were: permeation membranes and liquid-metal-covergas-interfaces to study the transport of H{sub 2}, D{sub 2} and {sup 3}H, different purification devices, a quartz observation window to see the liquid metal surface, 4 different kinds of flow measurements, level indicators, freeze valves. The second part describes loop operation. Between 1989 and 1996, the eutectic ...
Patients with haemarthros of the knee were examined by MRI and arthroscopy to identify the bleeding source and to determine surgical or conservative therapy. A prospective study was performed on 120 patients who underwent MRI and arthroscopy, point lesions and bleeding sources were documented separately on a standardised form. Arthroscopy demonstrated a ruptured anterior cruciate ligament in 86%, meniscal tears in 55%, disruption of collateral ligaments in 17%, osteochondral lesions in 5% and tears of capsule or plicae in 13%. Disruption of cruciate ligaments caused haemorrhage in all but three cases. In contrast, only meniscal tears located very adjacent to the meniscal basement had bled. Those types of osteochondral lesions caused haemorrhage characterised on MRI by destruction of the subchondral plate and overlying cartilage. Severe lesions of the knee were diagnosed by MRI in 71% to 100%, slight lesions in 13% to 40% of the cases. Single, combined and bland lesions were accurately ...
We present a method to make phantoms of coronary arteries for intravascular optical coherence tomography (IV-OCT). The phantoms provide a calibrated OCT response similar to the layered structure of...Full Text Available
Purpose: The aim of this study was to test the feasibility of iliac artery stent placement under MR guidance with real-time MR radial scanning in an animal model. Materials and methods: The experiments were performed on three pigs in a 1.5 T scanner. Radial scanning with a gradient echo technique (T{sub R} 8.4 ms, T{sub E} 3.6 ms, flip angle 10 ) was used. A dedicated backprojector performed the reconstruction of the raw data in real-time. The resulting MR-images were displayed on LCD screens beside the magnet. The sliding window reconstruction technique allowed image acquistion at a frame rate of 16 images per second. MR-compatible self-expanding stents with a diameter of 8 mm and a length of 3 cm were placed into the left iliac artery. Their positions were verified by digital subtraction angiography (DSA) and compared to MRI. Results: All stents were successfully placed. Stent positions as monitored by real-time MR were identical to those seen on DSA images. The time needed for exact ...
Purpose: In the present study the reduction of artifacts using an extended CT scale technique was examined in 5 vitallium and 5 titanium-aluminium-vanadium tumor prostheses. Methods: 5 titanium-aluminium-vanadium and 5 vitallium distal femur Mutars {sup trademark} tumor prostheses (Mutars {sup trademark} - Modular Universal Tumor And Revision System) were implanted in 10 human femur specimens. 110 artifical drill hole lesions of 1 mm, 2 mm, 3 mm, 5 mm and 8 mm diameter were placed in the bone around the hexagonal stem of the tumor prosthesis and furthermore in the proximal part of the femur. All specimens were examined using conventional CT and an extended CT scale technique in a slice thickness of 3 mm. Results: In the proximal part of the femur all drill holes could be detected using 3 mm slices, no artefacts were observed. Along the hexagonal stem smooth lines arising from each hexagonal plane could be observed. This made it impossible to detect a 1 mm drill in 1 vitallium and in 1 ...
This research project aimed to determine the factors for the transfer of the elements silver (Ag), cerium (Ce), cobalt (Co), chrome (Cr), gallium (Ga), lanthanum (La), molybdenum (Mo), niobium (Nb), radium (Ra), ruthenium (Ru), antimony (sb), thorium (Th), titanium (Ti) and uranium (U) from food into the mother's milk. This factors will be used as a basic to check and derive activity values for the contamination of food and for radiation protection at working places of suckling women. For this purpose 19 mothers collected samples daily (2-8 weeks), using the duplicate method, of all the food they consumed as well as of their milk. After microwave-assisted digestion the element contents were analysed by mass-spectroscopy with inductive coupled plasma (ICP-MS). The results of the mothers who participate for more than 5 weeks were used to make a time lapse between the intake and transfer of the elements in the mothers milk visible. (orig.) [German] Ziel dieses Forschungsvorhabens ...
Magnetic resonance imaging (MRI) of the lung is challenging because of substantial drawbacks. However, lung pathologies that are associated with increased attenuation values in CT enhance visualization in MRI: proton density is increased and tissue-air interfaces, resulting in susceptibility artifacts, are reduced in pneumonia, pneumonitis, edema, and carcinoma. On the other hand, many lung diseases result in shortness of breath, so that patients cannot hold their breath for long periods. Therefore, fast imaging techniques are required which should also allow for high spatial resolution so that small lesions can be detected. Calcifications and air pockets within lesions are not readily recognized with MRI. Thin section CT is standard for the diagnosis of pneumonia. With parallel imaging techniques, MRI examination of the lungs can be performed with short periods of breath holding, which allow for sub-centimeter resolution in the z-axis. Especially for follow-up examinations in ...
When the use of retarders in utility vehicles increased in the middle of the 80s, the Forschungsvereinigung Automobiltechnik (FAT) commissioned a study on the safety aspect of this braking technology in trucks. Retarders are wear-free permanent brakes that are fitted in the drive transmission system of utility vehicles, thereby generating braking forces only at the wheels of the live shaft. The question of the possible overbraking of the live shafts was just as well investigated as the interaction between the retarder and service brake in so-called integrated braking systems, and both under conditions of low adhesion as well as in the border area of the dynamics of vehicle movement. This subject met with considerable joint interest on the part of the motor vehicle industry as well as of manufacturers of towed vehicles and unit sets. FAT, therefore, commissioned the Institut fuer Kraftfahrwesen of the University of Hannover to carry out a three-phase research project on the braking ...
The basis of assessment for particulate exhaust emissions is the gravimetric analysis of the particle concentration of diluted exhaust gases at temperatures below 52 C. This is very time consuming and takes sufficient sensitivity at low particulate emission rates like downstream of particle filters. For this reason the C/S-method, based on the thermographic analysis of carbon and sulfur, has been developed as an alternative to the gravimetric anallysis. This method yields particle mass as well as the main particle compounds. Comparisons between both methods have been carried out for heavy duty and automobile diesel engines as well as road vehicles and large diesel engines. The tests were conducted with commercial diesel fuel and also with other fuels, such as heavy oils. It could be shown that the C/S-procedure yields the same results as the gravimetric procedure independent of engine, engine mode and kind of fuel. The analysis of all important particulate compounds - elemental carbon ...
We report for the first time about a micromachined mass flow sensor directly integrated between the double guidance and the needle seat into the body of a Common Rail (CR) injection nozzle. The thermal measurement principle was chosen because gaseous as well as liquid mass flows can be determined fast and precisely. Additionally, with glass-ceramic materials fabricated in a low cost batch process, a high temperature and especially pressure stable substrate can be used. The flow sensitive thin film is realized by an e-beam evaporated 110 nm thick molybdenum (Mo) layer. The latter is electrically characterized by the resistivity of {rho} = 8.2 x 10{sup -7} {omega} m ({+-}2%) at room temperature as well as by the first {alpha}=4.5 x 10{sup -4} K{sup -1} ({+-}5%) and second {beta}=3.0 x 10{sup -6} K{sup -2} ({+-}12%) temperature coefficients of resistance up to 300 C. The static temperature field at and around the thin film sensor on the glass-ceramic substrate is investigated with an IR ...
Currently daily quality control (QC) tests for mammography systems are generally evaluated by using visual analysis phantoms, which of course means subjective measurement. In our study, however, we evaluated a novel digital phantom, the 1Shot Phantom M plus (1Shot Phantom), together with automatic analysis software dedicated for mammography systems using Fuji computed radiography (FCR). The digital phantom enables objective evaluation by providing for actual physical measurement rather than subjective visual assessment. We measured contrast to noise ratio (CNR), image receptor homogeneity, missed tissue at chest wall side, modulation transfer function (MTF), and geometric distortion utilizing the 1Shot Phantom. We then compared the values obtained using the 1Shot Phantom with values obtained from the European guidelines and International ...
MRI provides a non-invasive diagnostic tool complementing echocardiography on one hand, and showing advantages over echocardiography, on the other hand, especially after corrective procedures. The multiple different MRI sequences need to be adapted to examinations of children and patients with congenital heart disease (CHD), and can be used to detect morphologic changes, blood-flow in the heart and thoracic vessels and diastolic or systolic function of myocardium. Several factors determine the success of the examination of a complex congenital heart disease or a postoperative situs. Pediatric radiologists and radiologists experienced in congenital heart diseases have to work in close cooperation. Echocardiography should be performed before MRI. The results of prior examinations and the clinical history of the patients, including possible palliative or reconstructive operations, must be available before MRI to guide the planning of the examination. With a systematic segmental approach ...
Purpose: The aim of this study was to evaluate the accuracy of MRI in the measurement of cartilage thickness of the ankle joint in comparison to pathologic and histologic specimens. Patients and methods: The ankle joints of four fresh cadaver feet were imaged on a 1.5 T MR-unit in the coronal plane. Standard T{sub 1}-weighted spin echo (SE) and a T{sub 1}-weighted 3D-GE (FLASH-3D) sequence with fat saturation were applied. Following MR imaging, the talus was explanted and cut parallel to the MR images for macroscopic evaluation and histologic specimens were prepared. MRI measurements of the cartilage thickness of the talus were carried out in two ways: Without and with consideration of a transition zone of intermediate signal intensity between hyperintense cartilage and hypointense cortical bone. The data were compared with the anatomic specimens as the gold standard expressing the difference as a percentage value. On histologic specimens thickness of deep calcified cartilage layer was ...
A phantom simulation imaging quality control device is described that effectively simulates one centimeter lesions, using steel ball bearings as gamma ray attenuators. The bearings are mounted in a synthetic resinous sheet in an orthogonal pattern. The phantom can provide uniformity, resolution, linearity, distortion and field size checks, all with a single exposure.
High dose rate (HDR) brachytherapy for treating a cervix carcinoma has become popular, because it eliminates many of the problems associated with conventional brachytherapy. In order to improve the clinical effectiveness with HDR brachytherapy, a dose calculation algorithm, optimization procedures, and image registrations need to be verified by comparing the dose distributions from a planning computer and those from a humanoid phantom. In this study, the humanoid phantom was fabricated in order to verify the absolute doses and the relative dose distributions. The measured doses from the humanoid phantom were then compared with the treatment planning system for the dose verification. The humanoid phantom needs to be designed such that the dose distributions can be quantitatively evaluated thermoluminescent dosimeter (TLD) chips with a dimension of 1/8 and film dosimetry with a spatial resolution of ...
Objective: To investigate the relationship between exposure dose and image quality for a direct digital radiography system and to determine the optimum exposure parameters for pelvic examination. Methods: A contrast-detail phantom CDRAD2.0 was exposed to different doses and the IQF of phantom images were calculated. The optimum exposure parameters were determined by ANOVA and SNK analysis. The image of an anthropomorphic phantom taken with optimized exposure parameters was verified using CEC image criteria. Results: The IQF of the images of CDRAD2.0 phantom was significantly different for different doses, as the exposure dose was greater than 0.61 mGy. The IQFs have no difference for different dose groups. The image quality between this optimized exposure dose and conventional exposure dose not was significantly different. Conclusion: The image quality of direct digital radiography system is improved as ...
We perform a detailed phase-space analysis of various phantom cosmological models, where the dark energy sector interacts with the dark matter one. We examine whether there exist late-time scaling attractors, corresponding to an accelerating universe and possessing dark energy and dark matter densities of the same order. We find that all the examined models, although accepting stable late-time accelerated solutions, cannot alleviate the coincidence problem, unless one imposes a form of fine-tuning in the model parameters. It seems that interacting phantom cosmology cannot fulfill the basic requirement that led to its construction.
We investigate several varying-mass dark-matter particle models in the framework of phantom cosmology. We examine whether there exist late-time cosmological solutions, corresponding to an accelerating universe and possessing dark energy and dark matter densities of the same order. Imposing exponential or power-law potentials and exponential or power-law mass dependence, we conclude that the coincidence problem cannot be solved or even alleviated. Thus, if dark energy is attributed to the phantom paradigm, varying-mass dark matter models cannot fulfill the basic requirement that led to their construction.
BackgroundStump and phantom pains are debilitating sequelae of amputations that are often resistant to treatment. The efficacy of pharmacologic therapies, including...Full Text Available
The aim of this work was to compare dose calculation algorithm results at orthovoltage energies for a phantom composed of a bone slab in water. The calculation methods investigated were: no correction, ETAR, Batho, convolution/superposition and Monte Carlo. All algorithms calculated depth dose curves in a water phantom within 4% of experiment. However in the bone phantom, differences of over 40% between the No Correction / ETAR / Batho / Convolution and Monte Carlo results in the 1 cm thick bone slab were observed. These differences are predominantly because the algorithms do not account for the differing atomic number of the bone compared to water The increased dose to bone and the tissue adjacent to the bone interface should be considered when treating with orthovoltage photons. Copyright (1998) Australasian Physical and Engineering Sciences in Medicine
ObjectiveTo describe the prevalence, intensity, and functional impact of the following types of pain associated with upper-limb loss: phantom limb, residual limb,...Full Text Available
Purpose: To visualise the vessel wall of the descending thoracic aorta using magnetic resonance imaging. To evaluate the diagnostic potential of tailored T{sub 1}-weighted sequences with contrast enhancement to assess systemic atherosclerotic disease. Methods: This study was performed on a clinical 1.5 Tesla scanner using a gradient strength of 30 mT/m and the phased array spine coil. A cadaver was examined to optimise a magnetic resonance imaging (MRI) protocol to evaluate atherosclerotic aortic wall disease. The acquired MR images were compared to gross specimens and histology. Subsequently seven patients who had undergone transesophageal ultrasound (TEU) with detailed assessment of the descending thoracic aorta were examined with MRI. The optimised protocol included untriggered and fat suppressed T{sub 2}-weighted turbo spin echo sequences and ECG-triggered and fat suppressed T{sub 1}-weighted spin echo sequences before and after iv administration of Gd-DTPA. Findings of the MR ...
A computer program for optimization of modular cogeneration plants is introduced. Computer calculation fundamentals are discussed referring to examples which elucidate the verification of the calculated data by measured data or empirical values. The results obtained as one optimizes plants by varying their size or by splitting them into modules are introduced referring to examples. Sensitivity analyses are made to investigate the influence of parameters such as fuel prices, electricity tariffs and interest rates. (orig.) [Deutsch] Im vorliegenden Beitrag wird ein Computerprogramm zur Optimierung von BHKW-Anlagen vorgestellt. Zunaechst werden in einem ersten Schritt die Berechnungsgrundlagen an einem Beispiel in Hinblick auf ihre Ueberpruefung durch Messdaten oder durch Erfahrungswerte diskutiert. Dann werden in einem zweiten Schritt exemplarisch die Ergebnisse einer Optimierung durch Variation der Gesamtanlagengroesse auf ...
Abstract Residual limb pain (RLP) and phantom limb pain (PLP) can be debilitating and can prevent functional gains following amputation. High correlations have been reported between RLP and the stump neuromas following amputation. Many treatment methods including physical therapy, medications, and interventions, have been used with limited success. Pulsed radiofrequency ablation (PRFA) has shown promise in treating neuropathic pain because of the inhibition of evoked synaptic activity. We present 4 amputees who were treated with PRFA after failing conservative management for their RLP and PLP. All 4 patients underwent PRFA and demonstrated at least 80% relief of RLP for over 6 months. One patient reported a complete resolution of phantom sensation while another patient had significantly de...
Details of the interaction of photons with tissue phantoms are elucidated using Monte Carlo simulations. In particular, photon sampling volumes and photon pathlengths are determined for a variety of scattering and absorption parameters. The Monte Carlo simulations are specifically designed to model light delivery and collection geometries relevant to clinical applications of optical biopsy techniques. The Monte Carlo simulations assume that light is delivered and collected by two, nearly-adjacent optical fibers and take into account the numerical aperture of the fibers as well as reflectance and refraction at interfaces between different media. To determine the validity of the Monte Carlo simulations for modeling the interactions between the photons and the tissue phantom in these geometries, the simulations were compared to measurements of aqueous suspensions of polystyrene microspheres in the wavelength range 450-750 nm.
It is often necessary to estimate the dose of radiation to a fetus from a series of CT scans. To assist in making this process easier and more accurate, we measured fetal doses in an adult anthropomorphic phantom for four CT scanners: Picker 1200, Siemens DRH, GE 9800, and GE 8800. Measurements were made at four kilovoltages (100, 120, 130, and 140 kVp), for 2-, 5-, 8-, and 10-mm thicknesses, for two scanning angles (360 degrees and 398 degrees) and for two patient orientations (prone and supine). The fetal-dose estimates are based on the CT dose index measured by using a pencil ionization chamber at the center position of a 16-cm-diameter cylindrical phantom. Comparison with data from other investigators shows reasonable agreement when phantom differences, X-ray tube output, and equipment calibration are considered.
This study investigated dose to bone tissue in electron beam therapy. Measurements were made using films and thermoluminescent dosimeters in a polystyrene phantom containing bone inhomogeneity for 15-MeV, 12-MeV, and 9-MeV electron beams. An increase in dose of approximately 18%, 12%, and 11%, for the three electron energies respectively, relative to the dose in polystyrene, was found for bone material having an electron density (relative to water) of 1.73. Measurements were also made using films for 15- and 9-Mev electrons in a phantom with a mandibular bone and teeth. A dose enhancement in bone of approximately 10% and 7%, respectively, for the two energies was found in the phantom where the electron density of bone was about 1.60. These results suggest that injury to bone is possible in those clinical situations where high doses of electrons are used for therapy.
This study investigated dose to bone tissue in electron beam therapy. Measurements were made using films and thermoluminescent dosimeters in a polystyrene phantom containing bone inhomogeneity for 15-MeV, 12-MeV, and 9-MeV electron beams. An increase in dose of approximately 18%, 12%, and 11%, for the three electron energies respectively, relative to the dose in polystyrene, was found for bone material having an electron density (relative to water) of 1.73. Measurements were also made using films for 15- and 9-Mev electrons in a phantom with a mandibular bone and teeth. A dose enhancement in bone of approximately 10% and 7%, respectively, for the two energies was found in the phantom where the electron density of bone was about 1.60. These results suggest that injury to bone is possible in those clinical situations where high doses of electrons are used for therapy.
The purpose of this study was to investigate the feasibility of a simple deformable phantom as a QA tool for testing and validation of deformable image registration algorithms. A diagnostic thoracic imaging phantom with a deformable foam insert was used in this study. Small plastic markers were distributed through the foam to create a lattice with a measurable deformation as the ground truth data for all comparisons. The foam was compressed in the superior-inferior direction using a one-dimensional drive stage pushing a flat 'diaphragm' to create deformations similar to those from inhale and exhale states. Images were acquired at different compressions of the foam and the location of every marker was manually identified on each image volume to establish a known deformation field with a known accuracy. The markers were removed digitally from corresponding images prior to registration. Different image registration algorithms were tested using ...
Subjective tinnitus, the phantom ringing or buzzing sensation that occurs in the absence of sound, affects 12–14% of adults; in some cases the tinnitus is so severe or disabling that...Full Text Available
The reference medium for brachytherapy dose measurements is water. Accuracy of dose measurements of brachytherapy sources is critically dependent on precise measurement of the source–detector...Full Text Available
Typical aircraft types supported include F4-Phantom, Tornado, MiG-29 ...... attempt to develop a theoretical explanation for learning phenomena [16]. ..... perspective, a primary reason for this is that an exponential curve approximates ...
The usefulness and clinical applicability of computed radiography(FCR) in X-ray examination of the stomach were evaluated in comparison with film-screen (FS) radiography by both phantom experiments and clinical studies. Receiver operating characteristic (ROC) curve analysis consisting of 25 normal and 25 artificially created simulated lesions on an orginally created Styrofoam phantom showed no difference in lesion detectability between FCR and FS radiography. Both were also equal in evaluation of the internal structure and margin of the 25 lesions by visual ranking. ROC curve analysis of clinical cases was performed in 30 cases, 20 normal and 10 abnormal, while evaluation by visual ranking was performed on 18 lesions. There was no significant difference between FCR and FS radiography either with ROC curve analysis or visual ranking, although the variations were somewhat greater in the clinical cases than in the phantom ...
The usefulness and clinical applicability of computed radiography(FCR) in X-ray examination of the stomach were evaluated in comparison with film-screen (FS) radiography by both phantom experiments and clinical studies. Receiver operating characteristic (ROC) curve analysis consisting of 25 normal and 25 artificially created simulated lesions on an orginally created Styrofoam phantom showed no difference in lesion detectability between FCR and FS radiography. Both were also equal in evaluation of the internal structure and margin of the 25 lesions by visual ranking. ROC curve analysis of clinical cases was performed in 30 cases, 20 normal and 10 abnormal, while evaluation by visual ranking was performed on 18 lesions. There was no significant difference between FCR and FS radiography either with ROC curve analysis or visual ranking, although the variations were somewhat greater in the clinical cases than in the phantom ...
We performed experimental studies on the convolution/superposition method reported in the former companion paper (Iwasaki in Radiol Phys Technol 4, 2011) using 10-MV X-ray beams from open-jaw-collimated fields. The method uses primary and scatter dose kernels formed for energy bins of X-ray spectra reconstructed as a function of off-axis distance. We made a comparison of calculations and measurements in water phantoms and thorax-like phantoms with respect to percentage depth dose curves, tissue???phantom ratio curves, and dose profiles. We made the dose calculation by taking into account the beam-hardening effect with depth and the off-axis radiation-softening effect. We found that the method could be used, in general, for performing accurate dose calculations.
The knowledge shown in this work of the relationships between the oxidation stage of chromium, molybdenum and tungsten and their catalytic activity in some hydrocarbon reactions was achieved by the combination of separate investigations of reduction properties and the catalytic activity of the catalysts concerned. To characterize the electronic state of the reduced surfaces, X-ray photo-electronic spectroscopy was mainly used, supplemented by electron spin resonance. The catalyst activity was measured in conventional apparatus (flow, pulse and gradient-free reactors). (orig.) [Deutsch] Die in dieser Arbeit dargestellten Erkenntnisse ueber die Zusammenhaenge zwischen der Oxidationsstufe von Chrom, Molybdaen und Wolfram und ihrer katalytischen Aktivitaet in einigen Kohlenwasserstoffreaktionen wurden durch die Kombination getrennter Untersuchungen ueber Reduktionseigenschaften und katalytische Aktivitaet der betreffenden Katalysatoren erzielt. Fuer die ...
The paper examines the influence of various total strain amplitudes and mean strains on the cyclic deformation processes in GGG-60 at temperatures of 20 C, 350 C, and 500 C ,the total strain amplitudes being varied between 1.0 permille {<=}{epsilon}{sub a,t}{<=}3.8 permille , and the mean strains between -4.0 permille {<=}{epsilon}{sub m,t}{<=}4.0 permille . - [Deutsch] In der Arbeit wird der Einfluss unterschiedlicher Totaldehnungsamplituden und Mitteldehnungen auf das Wechselverformungsverhalten von GGG-60 bei Temperaturen von 20 C, 350 C und 500 C untersucht. Dabei werden die Totaldehnungsamplituden zwischen 1,0 permille {<=} {epsilon}{sub a,t} {<=} 3,8 permille und die Mitteldehnungen zwischen -4,0 permille {<=} {epsilon}{sub m,t} {<=} 4,0 permille variiert. (orig./MM)
The clinical feasibility of using interventional examination techniques was tested with an equipment combining fluoroscopy and MR imaging. This hybrid system showed to be of advantage in a great number of interventional examinations. The 1.5 Tesla magnet proved to be superior to open MR scanning systems in terms of image quality and scanning times. (orig.) [Deutsch] Es wurde die klinische Durchfuehrbarkeit interventioneller Techniken an einem kombinierten Durchleuchtungs- und MR-Arbeitsplatz untersucht. Dieses Hybridsystem erwies sich bei einer Vielzahl interventioneller Eingriffe als vorteilhaft. Der 1,5 Tesla-Magnet ist offenen MR-Systemen hinsichtlich Bildqualitaet und Messzeit ueberlegen. (orig.)
The purpose of this study is to develop a geometrically accurate imaging protocol at 3 T magnetic resonance imaging (MRI) for stereotactic radiosurgery (SRS) treatment planning. In order to achieve this purpose, a methodology is developed to investigate the geometric accuracy and stability of 3 T MRI for SRS in phantom and patient evaluations. Forty patients were enrolled on a prospective clinical trial. After frame placement prior to SRS, each patient underwent 3 T MRI after 1.5 T MRI and CT. MR imaging protocols included a T1-weighted gradient echo sequence and a T2-weighted spin echo sequence. Phantom imaging was performed on 3 T prior to patient imaging using the same set-up and imaging protocols. Geometric accuracy in patients and phantoms yielded comparable results for external fiducial reference deviations and internal landmarks between 3 T and 1.5 T MRI (mean ?0.6 mm; standard deviation ?0.3 mm). Mean stereotactic ...
In interventional radiology (IVR) of cerebral aneurysms, it is important to understand the form and physical relationships between the cerebral aneurysm and the surrounding vessels. However, because the vessels in the head area are highly complex, it can be difficult to comprehend the structure using conventional angiography. Therefore, three-dimensional rotational angiography (3D-RA) has been used in recent years. This article discusses studies of the spatial resolution of 3D-RA. We reconstructed 3D-RA of an acrylic slit phantom (slit widths: 0.5, 0.75, 1.0, 1.5 mm) and examined spatial resolution by visual evaluation and profile curves. When the slit phantom was arranged to avoid the effect of beam hardening, the spatial resolution of 3D-RA was found to be as high as 0.75 mm. When the slit phantom was placed orthogonal to the rotational axis of the C-arm, the spatial resolution of 3D-RA was decreased because of the cone ...
Ultra-high resolution radiographs can be obtained using synchrotron X-rays. A collaboration team consisting of K-JIST, POSTECH and YUMC has recently commissioned a new beamline (5C1) at Pohang Light Source (PLS) in Korea for medical applications using phase contrast radiology. Relatively simple image acquisition systems were set up on 5C1 beamline, and imaging studies were performed for resolution test patterns, mammographic phantom, and animals. Resolution test patterns and mammographic phantom images showed much better image resolution and quality with the 5C1 imaging system than the mammography system. Both fish and mouse images with 5C1 imaging system also showed much better image resolution with great details of organs and anatomy compared to those obtained with a conventional mammography system. A simple and inexpensive ultra-high resolution imaging system on 5C1 beamline was successfully implemented. The authors were able to acquire ...
Several configurations of moderating and shielding materials have been designed and measured on the LVR-15 reactor for boron neutron capture therapy (BNCT) purposes. To determine the neutron and gamma ray space-energy distributions in the cylindrical geometry, the two-dimensional code DOT with the coupled neutron-gamma data library DLC-36 was used. The experimental verification of the beam parameters was performed in the LVR-15 reactor thermal column empty space with layers of graphite, aluminium, alumina, lead and bismuth. Attention was paid to establishing techniques and instrumentation for monitoring the neutron and gamma ray dose and beam quality. The thermal and epithermal flux densities were measured by activation foils, the neutron spectrum was determined with a Bonner spectrometer and gamma ray background with a scintillation spectrometer. The distribution of thermal neutrons in the human head phantom was mapped with a small semiconductor detector (Si[sup ...
Several configurations of moderating and shielding materials have been designed and measured on the LVR-15 reactor for boron neutron capture therapy (BNCT) purposes. To determine the neutron and gamma ray space-energy distributions in the cylindrical geometry, the two-dimensional code DOT with the coupled neutron-gamma data library DLC-36 was used. The experimental verification of the beam parameters was performed in the LVR-15 reactor thermal column empty space with layers of graphite, aluminium, alumina, lead and bismuth. Attention was paid to establishing techniques and instrumentation for monitoring the neutron and gamma ray dose and beam quality. The thermal and epithermal flux densities were measured by activation foils, the neutron spectrum was determined with a Bonner spectrometer and gamma ray background with a scintillation spectrometer. The distribution of thermal neutrons in the human head phantom was mapped with a small semiconductor detector (Si"6Li). ...
The composition of alkaline and neutral boric acid containing evaporator concentrates resulting from the treatment of radioactive waste water in nuclear power plants with WWER reactors is described as well as the processing of these concentrates to a product suitable for final disposal. Tests with mock solutions of these evaporator concentrates have been performed at the laboratory and teststand scale to produce a dry residue by continuous thickening, which can be processed into a highly leach resistant product, suitable for final disposal, by cementation. Ca-compounds must be added to the evaporator concentrates prior to the drying in an rotary thin-film evaporator (RTFE). The tests showed that neutral evaporator concentrates can be dried in a RTFE with addition of small amounts of Ca-compounds. The alkaline evaporator concentrates with high boric acid and total salt load require a multiple amount of Ca-compounds and diluting water to perform the drying process. A brief description of ...
The creep behaviour of boiler drums of CuNiMo steels depends on the ratio of the alloys, the heat treatment and the processing technology. Reduction in deformability must be expected but, under optimum conditions, this does not lead to a critical material condition. The appropriate material tests are indispensable. (orig.)
The MCNPE-BO and MCNP4 Monte Carlo electron-photon codes were used to calculate the dose equivalent per unit fluence at various depths in tissue-equivalent slab phantoms for broad parallel beams of monoenergetic electrons with energies from 50 keV to 10 MeV. The study was carried out in the framework of the activities of a ICRP/ICRU Joint Task Group with the support of EURADOS WG4 (Numerical Dosimetry). Some preliminary results and comparisons as well as a general discussion on the performances of the codes are presented, demonstrating quite a satisfactory agreement among the results obtained using the two codes and those of other authors. (author).
Purpose: In this paper, we present an alternative to the originally proposed technique for the delivery of spatially fractionated radiation therapy (GRID) using multi-leaf collimator (MLC) shaped fields. We employ the MLC to deliver various pattern GRID treatments to large solid tumors and dosimetrically characterize the GRID fields. Methods and materials: The GRID fields were created with different open to blocked area ratios and with variable separation between the openings using a MLC. GRID designs were introduced into the Pinnacle3 treatment planning system, and the dose was calculated in a water phantom. Ionization chamber and film measurements using both Kodak EDR2 and Gafchromic EBT film were performed in a SolidWater phantom to determine the relative output of each GRID design as w...
This paper develops a fluid dynamic model using finite difference methods characterizing flow in phantoms simulating in vivo conditions and to compare those results with velocity encoded MR images. The phantom consisted of 1-inch (2.5-cm) tubing with semicircular insert and fluid with viscosity, T1, and T2 comparable to blood. Numeric solutions to Navier-Stokes equations for this system were obtained using finite difference methods, with velocity input function of zero at walls and parabolic at both ends. In resulting color raster (CR) images, color temperature represented velocity value. In velocity-encoded MR images acquired under the same flow conditions, phase is proportional to average velocity during application of flow-encoding gradients. Because these gradients are applied along one direction per acquisition, magnitude and direction of velocity are obtained.
Ultrasound tomography is an attractive imaging method for the detection of breast cancer. The complex anatomy of the breast with its different spatial scales and material property contrasts make accurate reconstructions very challenging. This paper proposes a hybrid approach whereby Travel-of-Flight and Diffraction Tomography are combined together to achieve high-resolution and high-accuracy sound-speed reconstructions. The method is validated with several numerical phantoms.
Currently, x-ray mammography is the method of choice in breast cancer screening programmes. As the mammography technology moves from 2D imaging modalities to 3D, conventional computational phantoms do not have sufficient detail to support the studies of these advanced imaging systems. Studies of these 3D imaging systems call for a realistic and sophisticated computational model of the breast. DeBRa (Detailed Breast model for Radiological studies) is the most advanced, detailed, 3D computational model of the breast developed recently for breast imaging studies. A DeBRa phantom can be constructed to model a compressed breast, as in film/screen, digital mammography and digital breast tomosynthesis studies, or a non-compressed breast as in positron emission mammography and breast CT studies. Both the cranial-caudal and mediolateral oblique views can be modelled. The anatomical details inside the phantom include the lactiferous ...
A method of reconstructing three-dimensional, in vivo dose distributions delivered by intensity-modulated radiotherapy (IMRT) is presented. A proof-of-principle experiment is described where an inverse-planned IMRT treatment is delivered to an anthropomorphic phantom. The exact position of the phantom at the time of treatment is measured by acquiring megavoltage CT data with the treatment beam and a research prototype, flat-panel, electronic portal imaging device. Immediately following CT imaging, the planned IMRT beams are delivered using the multiple-static field technique. The delivered fluence is sampled using the same detector as for the CT data. The signal measured by the portal imaging device is converted to primary fluence using an iterative phantom-scatter estimation technique. This primary fluence is back-projected through the previously acquired megavoltage CT model of the phantom, with ...
A simple dose-saving procedure for the diagnosis of congenital hip dysplasia employing a diaphragm in nearfocus position is presented. Doses to the skin and the gonads were measured with a phantom for the new and other techniques. With optimal techniques the skin dose is smaller than 2 mR and the gonadal doses lie around 0.1 mR for both male and female patients. An estimate of the dose burden from undesired radiation is appended. (orig.).
Bone images obtained by single exposure dual energy subtraction with computed radiography, a new image processing method, were evaluated for the detectability of calcification in lung nodules in both phantom and clinical studies. In the phantom study, five simulated nodules containing known and uniformly distributed amounts of calcium hydroxide were placed in a human chest phantom and images were obtained the following five techniques: (1) conventional radiography (CXR), (2) low kV conventional radiography (Low), (3) Fuji computed radiography (FCR), (4) bone images with conventional singles exposure energy subtraction (ES) and (5) bone image with fine single exposure energy subtraction (FES). The detectability of calcification in the simulated nodules was evaluated by six radiologists using ROC analysis and two-way analysis of variance. In the clinical study, images of 42 lung nodules (21 calcified lung nodules and 21 ...
Bone images obtained by single exposure dual energy subtraction with computed radiography, a new image processing method, were evaluated for the detectability of calcification in lung nodules in both phantom and clinical studies. In the phantom study, five simulated nodules containing known and uniformly distributed amounts of calcium hydroxide were placed in a human chest phantom and images were obtained the following five techniques: 1) conventional radiography (CXR), 2) low kV conventional radiography (Low), 3) Fuji computed radiography (FCR), 4) bone images with conventional singles exposure energy subtraction (ES) and 5) bone image with fine single exposure energy subtraction (FES). The detectability of calcification in the simulated nodules was evaluated by six radiologists using ROC analysis and two-way analysis of variance. In the clinical study, images of 42 lung nodules (21 calcified lung nodules and 21 ...
A novel phantom has been developed to measure the modulation transfer function (MTF) in 3D for x-ray computed tomography. The phantom consists of three tungsten wires, positioned nearly orthogonal to each other. Simultaneous measurements of the MTF are taken at various locations along the three orthogonal reconstructed planes. Our computed mammotomography (CmT) system uses a Varian Paxscan 2520 digital x-ray detector which can be positioned anywhere in ~2pi steradian band and can have arbitrary trajectories. With a half-cone beam geometry and with the phantom positioned near the center of rotation, projection images are acquired over 360 degrees. Various 3D orbits are evaluated including vertical axis of rotation and saddle. Reconstructions were performed using an iterative ordered-subsets transmission algorithm on rebinned projection images, using various numbers of iterations. Rotation of reconstructed slices isolated ...
Quantitative evaluation of CRT and CR observations in indentification of malignancy using phantom and clinical data. A breast phantom and a total of 40 patients were imaged by Fuji computed radiography (FCR). The images were interpreted twice by six radiologists both on CR film (2510 x 2000 pixels x 10 bits, 0.1 mm spatial resolution) and on a CRT monitor (1568 x 1152 pixels x 10 bits, 0.1 mm pixel size with double expansion) with image processing parameters of a toutine (RN 1.0, RE 0.2), for a calcification (RN 9.0, RE 4.0) and for a mass (RN 7.0, RE 2.0). The forty clinical cases included breast diseases with calcifications, masses, and normal breasts. Two-tailed t-test was performed to analyze interpretation of simulated microcalcifications and masses in the phantom. The receiver operating characteristic (ROC) analysis was performed to evaluate clinical cases. In all interpretation studies using both breast ...
Full text: Verification of the dose delivered to a patient during radiotherapy is an important quality assurance procedure, however this is rarely performed due to the extra time involved. Electronic portal images (EPIs) are currently acquired at many centres during radiotherapy treatment for positioning verification. These could be utilised for dose verification provided 1) an accurate prediction of the dose transmitted through the patient to the EPID can be produced for the patients' radiotherapy beams, and, 2) the EPID image can be converted to an accurate measured dose. Ideally, the radiotherapy planning system (RTPS) would be used to produce the predicted dose as part of the planning procedure. The aim of this project is to investigate whether the convolution-superposition model of the Pinnacle RTPS can accurately calculate dose transmitted through a patient and deposited in a phantom at a large source to surface distance. The dose transmitted through a ...
This is the first interdisciplinary approach to urban water and waste water managment. The author presents the knowledge acquired during the project. [German] Die ganzheitliche Betrachtung der Wasserwirtschaft in urbanen Gebieten ist sowohl in der Forschung als auch in der Praxis neu. Zwischen der Bearbeitung eines Forschungsprojektes und eines Ingenieurprojektes gibt es grundsaetzliche Differenzen, trotzdem sind wir der Meinung, dass es bezueglich der interdisziplinaeren Aspekte und der ganzheitlichen Betrachtung der Wasserwirtschaft sowohl in der Forschung als auch in der Praxis aehnliche Probleme gibt. Aus diesem Grunde wird in dieser Arbeit versucht ueber einige Erfahrungen aus dem interdisziplinaeren und ganzheitlichen Forschungsprojekt zu berichten. (orig.)
The first equipment installed at KfK-HDB was a system with a thin-film evaporator. This was later replaced by two vapor compression evaporating units with forced circulation, for evaporation of liquid LAW, and a steam-heated natural circulation evaporator, for evaporation of liquid MAW. Nuclear activities of the Karlsruhe Nuclear Research Center phasing out, the liquid radwaste quantities to be treated have been shrinking accordingly, so that the current system is planned to be replaced by a smaller system with a thin-film evaporator. (orig./HP) [Deutsch] Im Laufe der Jahre wurde die Anlage mit Duennschichtverdampfer durch zwei Bruedenkompressionsverdampfer mit Zwangsumwaelzung fuer die Eindampfung leicht aktiver waessriger Abfaelle und einem dampfbeheizten Naturumlaufverdampfer fuer die Eindampfung mittelaktiver waessriger Abfaelle ersetzt. Mittlerweile sinkt der Abwasseranfall seit Jahren stetig aufgrund der sinkenden Aktivitaeten des Zentrums auf dem Gebiet der ...
Report by a participant in the International Nuclear Law School. In 2001, this advanced training course was first offered by the OECD-NEA together with the University of Montpellier and other international partners. This effort is intended to provide an overview of nuclear law, a discipline normally playing a subordinate role in curricula. In this way, a contribution is to be made to the important preservation of the existing knowledge base and to increasing know-how in this field. In 2003, the International Nuclear Law School will be continued with a new curriculum addressed to all interested participants. (orig.) [German] Erfahrungsbericht eines Teilnehmers der Internationalen Schule fuer Nuklearrecht 2002 an der Universitaet Montpellier. Erstmals im Jahr 2001 wurde diese Fortbildungsveranstaltung von der Nuclear Energy Agency der Organisation for Economic Co-operation and Development (OECD-NEA) zusammen mit der Universitaet Montpellier und weiteren internationalen ...
The legal basis to be provided is a licence for decommissioning work, issued for a particular reactor, including activities for recycling of disassembled, radioactive components and materials, subject to radioactivity measurements and exemption from radiological control of materials not exceeding the legally defined maximum level of contamination. (HP) [Deutsch] Es genuegt eine Stillegungsgenehmigung zu einem konkreten Abbauauftrag mit Verwertung radioaktiver Reststoffe nach Freigabe durch Radioaktivitaetsgrenzwertsfestsetzung. (HP)
There are many applications that necessitate reliable and permanent power supply, e.g. power stations, airports, computer centers or hospitals. The stationary battery systems must be monitored by efficient systems, e.g. Batlog. (orig.) [Deutsch] Viele Anwendungen verlangen eine permanent verfuegbare und zuverlaessige Stromversorgung. Kraftwerke, Flughaefen, Rechenzentren oder Krankenhaeuser muessen ihre Prozesse auch bei einem Netzausfall oder einer Versorgungsunterbrechung weiterbetreiben. Dies gelingt nur, wenn sich der entsprechende Energiespeicher in einsatzbereitem Zustand befindet. Die Ueberwachung der stationaeren Batterieanlagen erfordert leistungsfaehige Systeme wie Batlog. (orig.)
In view of current trends in motor car development, the author investigates the increasing conflict between higher comfort and lower fuel consumption. The conflict results mainly from insufficient cooling water heating with consumption-optimized engines. So far, it was never necessary to analyze heat flow after cold starting and heat-up of the powertrain, to develop strategies for heat storage and distribution, to remove heat sinks and to use components multifunctionally. The contribution shows that a general heat management strategy for the whole vehicle will result in high potential fuel savings and improved thermal comfort. Using the example of a latent heat store, heating strategies for the engine and transmission system on the one hand and the passenger compartment on the other hand are developed, and the advantages are presented in detail. [German] Abgeleitet aus den Trends in der Fahrzeugentwicklung wird auf den immer staerker werdenden Konflikt zwischen den ...
Neutron and gamma ray energy spectra were measured using an NE-213 scintillator at depths of 7.2, 15.2, and 22.2 cm in a tissue-equivalent phantom which was uniformly irradiated on one face by deuterium--tritium (DT) neutrons. Coupled neutron--gamma ray multigroup discrete-ordinates calculations were performed using semi-infinite slab geometry. These calculations were used to supplement the measured spectra below 1 MeV. Similar calculations were performed to study the perturbation in the phantom due to the detector. The measured and calculated spectra were used to determine the kerma distributions for neutrons and gamma rays at each location. The gamma radiation was determined to contribute more than 10% of the total dose at each depth. The calculated kerma also reveals that a knowledge of the gamma ray spectra below 1 MeV is desirable. Key words: neutron--gamma spectra, spectrometry, kerma distributions, coupled multigroup calculations
Neutron and gamma ray energy spectra were measured using an NE-213 scintillator at depths of 7.2, 15.2, and 22.2 cm in a tissue-equivalent phantom which was uniformly irradiated on one face by deuterium--tritium (DT) neutrons. Coupled neutron--gamma ray multigroup discrete-ordinates calculations were performed using semi-infinite slab geometry. These calculations were used to supplement the measured spectra below 1 MeV. Similar calculations were performed to study the perturbation in the phantom due to the detector. The measured and calculated spectra were used to determine the kerma distributions for neutrons and gamma rays at each location. The gamma radiation was determined to contribute more than 10% of the total dose at each depth. The calculated kerma also reveals that a knowledge of the gamma ray spectra below 1 MeV is desirable. Key words: neutron--gamma spectra, spectrometry, kerma distributions, coupled multigroup calculations.
Postamputation pain (PAP) affects over 60% of major limb amputees. One of the main challenges in treating PAP is the difficulty involved in identifying pain mechanism(s), which pertains to both residual limb pain (RLP) and phantom limb pain (PLP). In this study, sympathetic blocks were performed on 17 major limb amputees refractory to treatment, including 2 placebo-controlled blocks done for bilateral amputations. One hour postinjection, mean RLP scores at rest declined from 5.2 (SD 2.8) to 2.8 (SD 2.6) (P = .0002), and PLP decreased from 5.3 (SD 3.1) to 2.3 (SD 2.1) (P = .0009). By 1 week, mean pain scores for RLP and PLP were 4.3 (SD 2.9) and 4.2 (SD 3.0), respectively. Overall, 8 of 16 (50%) patients experienced ?50% reduction in RLP 1-hour postinjection, with the beneficial effects ...
We developed a new TLD array for precise dose measurement and verification of the spatial dose distribution in small radiation targets. It consists of a hemicylindrical, tissue-equivalent rod made of polystyrene with 17 parallel moulds for an exact positioning of each TLD. The spatial resolution of the TLD array was evaluated using the Leskell spherical phantom. Dose planning was performed with KULA 4.4 under stereotactic conditions on axial CT images. In the Leksell gamma unit the TLD array was irradiated with a maximal dose of 10 Gy with an unplugged 14 mm collimator. The doses delivered to the TLDs were rechecked by diode detector and film dosimetry and compared to the computer-generated dose profile. We found excellent agreement of our measured values, even at the critical penumbra decline. For the 14 mm and 18 mm collimator and for the 11 mm collimator combination we compared the measured and calculated data at full width at half maximum. This TLD array may be ...
Purpose: calculation of conversion coefficients for the reconstruction of organ doses from entrance doses for abdomen radiographs of 0, 1, 5, 10, 15, and 30-year-old patients in conventional pediatric radiology for the radiographic settings recommended by the German and European guidelines for quality management in diagnostic radiology. Materials und method: using the commercially available personal computer program PCXMC developed by the Finnish Center for Radiation and Nuclear Safety (Saeteilyturvakeskus STUK), conversion coefficients for conventional abdomen radiographs were calculated performing Monte Carlo simulations in mathematical hermaphrodite phantom models describing patients of different ages. The possible clinical variation of beam collimation was taken into consideration by defining optimal and suboptimal radiation fields on the phantoms' surfaces. Results: conversion coefficients for the reconstruction of organ does in ...
A technique capable of measuring the electron energy fluence spectra in a scattering medium was designed. These measurements were performed by setting a bremsstrahlung conversion target on the surface of a phantom, at an intermediate depth, and at a depth equal to electron mean range. The bremsstrahlung produced by the deceleration of electrons in the target was passed through an air channel in the phantom and passed forward by a pinhole collimator into a Na(Tl) detector. The measured pulse height data were unfolded to correct for the distortion of the spectrometer system by using the FORIST unfolding code. The unfolded bremsstrahlung spectra represent the electron energy fluence spectra convolution with the bremsstrahlung produced in the target. To generate the electron energy fluence spectra, the unfolded bremsstrahlung spectra were deconvoluted by using the MAZE2 unfolding code. CYLTRAN, a coupled electron-photon Monte Carlo transport code, ...
The temperature elevations in anatomically based human phantoms of an adult and a 3-year-old child were calculated for radio-frequency whole-body exposure. Thermoregulation in children, however, has not yet been clarified. In the present study, we developed a computational thermal model of a child that is reasonable for simulating body-core temperature elevation. Comparison of measured and simulated temperatures revealed thermoregulation in children to be similar to that of adults. Based on this finding, we calculated the body-core temperature elevation in a 3-year-old child and an adult for plane-wave exposure at the basic restriction in the international guidelines. The body-core temperature elevation in the 3-year-old child phantom was 0.03 deg. C at a whole-body-averaged specific absorption rate of 0.08 W kg{sup -1}, which was 35% smaller than in the adult female. This difference is attributed to the child's higher body surface ...
The aim of the present study focuses on experimentally demonstrating the efficacy of using angularly-variable fiber geometry to achieve the desired tissue-layer selection and probing depths with the further objective of enhancing the sensitivity and specificity of spectral diagnosis in stratified architectures that resemble human cervical epithelia. The morphological and biochemical features of epithelial tissue vary in accordance with tissue depths; consequently, the accuracy of spectroscopic diagnosis of epithelial dysplasia may be enhanced by probing the optical properties of this tissue. When correlated to cellular dysplasia, layer-specific changes in tissue optical properties may be deciphered by reflectance spectroscopy coupled with angularly-variable fiber geometry. This study addresses the utility of using such angularly-variable fiber geometry for resolving spatially-specific spectral signatures of tissue pathology. This is accomplished by interpreting and analyzing the ...
The principle of radiodiagnosis consists in the fact the X-ray beam is attenuated at different degrees by distinct tissues. For this reason, the anatomical structures have distinct radiological opacities, that produce the radiographic image. The progresses in radiology are related to the development if new radiographic image formation systems that enable an amplification in the quality, with low dose and/or risk to the patient. The objective of this work is the sensitometric valuation of a screen-film combination, that is still the most used, for the standardization, of radiographic images. Thinking about this, were constructed homogeneous phantoms of the chest, skull and pelvis, for the calibration of X-ray beams, with the purpose of obtaining radiographic images of good quality, basing in the routine of a radiodiagnosis service and in the scientific knowledge. Questions were approached about the choice of the suitable equipment, that allow the obtention of k Vp ...
In an effort to evaluate the feasibility of introducing computed radiography (FCR) into mass screening for lung cancer, the ability of FCR to detect nodules one cm in diameter was examined using a humanoid chest phantom. Based on the receiver operating characteristic (ROC) analysis, the detectability of FCR was compared with that of conventional radiography and photofluorography. The values of area under ROC curves were higher for FCR (0.963 for image similar to that with conventional film-intensifying screen system, image A; and 0.952 for processed image, image B) than the other two methods (0.774 for radiography and 0.789 for photofluorography). Degradation of image quality in FCR could be avoided by a wide latitude even if proper exposure techniques might not be employed. Images A and B in FCR yielded excellent delineation for nodules in the lung field and in the retrocardiac and subdiaphragmatic regions, respectively. This may have implications for the value of ...
This paper shows the efficacy of computed radiography for major airway in pediatrics. For this purpose, we examined 40 children (range 2 weeks to 14 years; mean 2.3 years) using Fuji Computed Radiography (FCR) and radiation dose using pediatric phantom under FCR and conventional film and screen system. In comparison study with FCR and conventional film and screen system, FCR images are superior to conventional system in all cases. Scorings were done for the quality of the image of the pharynx, the trachea, and both main bronchi. In phantom study to check radiation dose, radiation dose could be reduced 1/6 of the value using high speed film and screen and 1/15 of the value using conventional speed film and screen. FCR also showed clear airway images in all cases but technical failure to evaluate the clinical lesion. These results suggest that FCR is the adequate imaging modality to evaluate the major airway in children. (author).
The calculation of electronn beam dose using an algorithms similar to convolution/superposition methods for photon beams [1,2,3,4] is explored. The distribution of dose deposited by a number of monoenergetic, point-monodirectional electron pencil beams is first determined using the Monte Carlo method [5,6]. These elementary distributions are combined to model distributions that would result from the spectrum of incident energies and angles [6,7] present in a clinical beam. These modified distributions are then stored for use as kernels in the dose calculation. In the case of a homogeneous phantom, the relative fluence distribution is convolved with the stored kernels to obtain thhe dose distributions in 3 dimensions. Since the kernels cannot be assumed to be spatially invariant in a heterogeneous water-like phantom, the dose deposited on paths from the interaction site to all the dose deposition sites is approximated by scaling the kernels to ...
While there have been many experimental and calculational investigations on absorbed dose distribution in the patient resulting from conventional X-ray procedures, such data for computerized tomography (CT) are still sparse. As this diagnostic procedure has shown a rapid increase in application during recent years, we have determined absorbed dose to body organs in a human phantom resulting from CT examinations. The exposure model consists of the heterogeneous MIRD-5 phantom and a suitable Monte-Carlo method to calculate absorbed dose to organs of interest. The exposure conditions are specified according to the exposure specifications of a CT-scanner currently in use. The calculations cover the range of body tissues of interest in terms of organ absorbed doses as well as a risk weighted absorbed dose. A detailed example showing the calculation of red bone marrow dose is given and a somatic effective dose equivalent Hsub(ES) is calculated for ...
Advanced modality of high-precision radiotherapy fulfilled by a composition of large numbers of small field beams called 'beamlets' can be achieved via nonuniform intensity fluencies. In case of radiation measurements and calculations with narrow high-energy photon beams, however, an accurate two-dimensional dosimetry is a challenging task due to dosimetrically unfavorable phenomena such as dramatic changes of the dose at the field boundaries, dis-equilibrium of the electrons resulting from larger detector volume, and non-uniformity between the detector and the phantom materials. Meanwhile, with the advantages of high spatial resolution and wide range of absorbed doses, there is a growing demand of GAFCHROMICat..EBT film to confirm delivered dose distribution. Especially, the effects from the material differences between the phantom and the film can be minimized in the heterogeneous condition since the GAFCHROMICat..EBT film is composed of ...
A first-principles task-based approach to the design of medical ultrasonic imaging systems for breast lesion discrimination is described. This study explores a new approximation to the ideal Bayesian observer strategy that allows for object heterogeneity. The new method, called iterative Wiener filtering, is implemented using echo data simulations and a phantom study. We studied five lesion features closely associated with visual discrimination for clinical diagnosis. A series of human observer measurements for the same image data allowed us to quantitatively compare alternative beamforming strategies through measurements of visual discrimination efficiency. Employing the Smith-Wagner model observer, we were able to breakdown efficiency estimates and identify the processing stage at which performance losses occur. The methods were implemented using a commercial scanner and a cyst phantom to explore development of spatial filters for systems ...
A convolution/superposition method is proposed for use with primary and scatter dose kernels formed for energy bins of X-ray spectra reconstructed as a function of off-axis distance. It should be noted that the number of energy bins is usually about ten, and that the reconstructed X-ray spectra can reasonably be applied to media with a wide range of effective Z numbers, ranging from water to lead. The study was carried out for 10-MV X-ray doses in water and thorax-like phantoms with the use of open-jaw-collimated fields. The dose calculations were made separately for primary, scatter, and electron contamination dose components, for which we used two extended radiation sources: one was on the X-ray target and the other on the flattening filter. To calculate the in-air beam intensities at po...
Surface doses received by patients and operators were measured during 30 interventional radiological procedures (ten percutaneous transhepatic biliary drainages, ten percutaneous nephrostomies, ten percutaneous transluminal angioplasties). In addition, organ doses to the patient were determined using an Alderson-Rando phantom. These served as a basis for calculating the so-called somatic dose indices. It was found that the somatic radiation risk to the patient is relatively small despite prolonged periods of fluoroscopy. However, exposure of the hands and lenses of the operator could easily reach the limits thought acceptable while carrying out these procedures with additional angiography. (orig).
Doses to the salivary glands, thyroid gland, breast, lung, stomach and colon during mass radiological gastric screening, mass radiographic chest screening, upper gastrointestinal series and computed tomography were determined by exposing a female human phantom to simulated radiological X-ray examinations as performed in community hospitals. The doses were measured using thermoluminescent dosemeters, and the results will be used to document organ doses received by participants in the Atomic Bomb Casualty Commission/Radiation Effects Research Foundation Adult Health Study. (Author).
Doses to the salivary glands, thyroid gland, breast, lung, stomach and colon during mass radiological gastric screening, mass radiographic chest screening, upper gastrointestinal series and computed tomography were determined by exposing a female human phantom to simulated radiological X-ray examinations as performed in community hospitals. The doses were measured using thermoluminescent dosemeters, and the results will be used to document organ doses received by participants in the Atomic Bomb Casualty Commission/Radiation Effects Research Foundation Adult Health Study. (Author).
Organ and tissue doses and integral doses in patients due to diagnostic x-ray examinations of the chest and of the head will be presented. These data have been obtained by measuring the dose distributions in man phantoms by LiF-dosimetry. The data will be compared with data obtained by Monte-Carlo calculations. To obtain average organ doses for a special type of examination for the population or for a specified subpopulation in the variation of the exposure, data due to the different techniques used by the different radiologists has to be known. Such data will be presented. The results of the investigation will be discussed in connection with the concept of the 'somatic significant.
In order to calculate the doses received by the organs of 530 children treated by radiation for cancer between 1945 and 1969 at the G. Roussy Institute, we have developed a computer program for organ location calculation. To calculate the location of each child's organs of interest at the time of the treatment, only two parameters are necessary; sex and height or sex and age when the height at the time of the treatment is unknown. The algorithm is based on the metric studies of growth known as auxology. Each organ is located by one point representing its center. The model has been checked on 100 healthy children.
Electron beam therapy has often been used for radiation therapy of carcinomas of the buccal mucosa, though side effects, including stomatitis and dermatitis, are known to exist. We experimented using the additional back scatter and transit with the phantom under a lead plate within the irradiation field, in order to better focus the dose on the target volume moreover, we fabricated a mouthpiece fitted with a lead plate shaped to the target volume, and with respect to the influence of the mouthpiece on stomatitis and dermatitis, obtained good clinical results. (author).
Electron beam therapy has often been used for radiation therapy of carcinomas of the buccal mucosa, though side effects, including stomatitis and dermatitis, are known to exist. We experimented using the additional back scatter and transit with the phantom under a lead plate within the irradiation field, in order to better focus the dose on the target volume moreover, we fabricated a mouthpiece fitted with a lead plate shaped to the target volume, and with respect to the influence of the mouthpiece on stomatitis and dermatitis, obtained good clinical results. (author).
Comparison of dosimetry measured in a noncylindrical Rando-Alderson phantom by two-field, four-field, and six-field total-skin electron-beam therapy (TSEBT) techniques with our dual-field rotational (DFR) technique reveals a superior dosimetry for the latter. Our technique of dual-field rotational DFR-TSEBT is described in detail, and its advantages and indications for the primary management of cutaneous T-cell lymphoma (CTCL) and Kaposi's sarcoma (KS) are discussed.
Purpose/Objective: With the advent of computed tomography and magnetic resonance imaging, the three dimensional representation of the patient anatomy has become an invaluable resource for better diagnosis and delineation of the target volume and sensitive structures in radiation therapy. Although the therapeutic linear accelerator industry has made available highly sophisticated equipment, the aggressiveness in dose prescription and delivery has to be complimented by accurate dose computation methods. We have adopted a convolution/superposition algorithm for the calculation of absolute dose that fully accounts for the external shape and internal structure of the patient for photon treatment radiotherapy. In this paper, we will discuss the principles of the convolution algorithm and we will show how the computed dose compares to clinically relevant treatment techniques. Materials and Methods: A computer controlled data acquisition system and a water tank where used to measure depth ...
We have developed a new type personal dosemeter by using a B-10 doped silicon p-n junction detector with a polyethylene radiator and a polyethylene moderator. The purpose of this study was to develop a real time neutron dosemeter with a nearly flat response in the energy range from thermal to 15 MeV and low angular dependence to the incident neutron direction. The neutron response of the dosemeter was obtained with the Monte Carlo calculation and the monoenergetic neutron experiment in a free air field and also under a condition attached on a phantom.
Full text: Semiconductor detectors coated with boron or lithium compounds have been studied for neutron detection for decades but, until recently, have been limited to thermal neutron detection efficiencies of less than 5%. We reported previously on development and simulation studies of perforated detectors whose perforations are filled with neutron-reactive material in order to produce higher detection efficiencies. Incorporation of bare and cadmium-backed detectors into battery-powered devices with low-power electronics enables us to produce compact personal neutron dosimeters that provide LED readout of counts, which can be related approximately to neutron dose. We report here on experimental studies with such compact devices; devices capable of direct readout in dose units are anticipated. The thermal and epithermal neutron flux densities from the tangential beam tube of the TRIGA Mark II reactor at Kansas State University were measured. Then, thermoluminescent dosimeters (some ...
The convolution/superposition calculations for radiotherapy dose distributions are traditionally performed by convolving polyenergetic energy deposition kernels with TERMA (total energy released per unit mass) precomputed in each voxel of the irradiated phantom. We propose an alternative method in which the TERMA calculation is replaced by random sampling of photon energy, direction and interaction point. Then, a direction is randomly sampled from the angular distribution of the monoenergetic kernel corresponding to the photon energy. The kernel ray is propagated across the phantom, and energy is deposited in each voxel traversed. An important advantage of the explicit sampling of energy is that spectral changes with depth are automatically accounted for. No spectral or kernel hardening corrections are needed. Furthermore, the continuous sampling of photon direction allows us to model sharp changes in fluence, such as those due to collimator ...
This paper deals with the externally coal-fired combined cycle (EFCC). A process simulation for different configurations of the EFCC-process is carried out as well as an investigation of the effect of the key parameters such as the gas turbine inlet temperature and the compressor intake airflow. The results show a promising potential of the efficiency. One component of this combined gas and steam turbine cycle is a high temperature heat exchanger that has to withstand the extrem chemical and thermal operating conditions. Fibre reinforced ceramics and combinations of them with monolithic ceramics seem to be the most promising materials for this application. A cost estimating of the EFCC-process shows that a competitive operation should be possible. (orig.) [Deutsch] Die Ergebnisse der Prozesssimulationen weisen ein vielversprechendes Wirkungsgradpotential des extern kohlebefeuerten Gasturbinenprozesses auf. Der fuer dieses neue Kraftwerkskonzept notwendige Hochtemperatur-Waermetauscher ...
One aspect of the research program SFB 570 'Distortion engineering' is the in situ X-Ray diffraction analysis of phases and residual stresses during complete heat treatment cycles. These investigations result in experimental evidence available for the extensive computations. The optimisation of the instrumentation will be reported. A surface decarburisation of samples made from the ball bearing steel 100Cr6 could be avoided for a temperature range from 800 to 900 C and a holding time of one hour by a combination of evacuate the furnace and using a certain nitrogen flow as protective gas. At lower temperatures small amounts of ferrite caused by an increased diffusion rate of carbon lead again to a surface decarburisation up to a depth of 2 {mu}m. It was proved that with an evacuation of the X-Ray beam path at constant power of the X-Ray source the intensity of diffraction lines could be increased by more than a factor of 4. The use of nitrogen as protective gas instead ...
The following industrial-scale power station processes are compared with natural gas/light fuel oil heating: Conventional steam generation, steam generation with gas turbine upstream, gas turbine process with low-pressure-waste heat boiler and cogeneration. Industrial gas turbines between 10 and 25 MW are compared with one another; typical boilers and industrial turbines are described. CO{sub 2} and NO{sub x} emissions are indicated. The steam turbines used are the efficient and robust turbines used in industry, wherever possible they are built as single-line plant with the gas turbine. (orig.) [Deutsch] Es werden folgende Industriekraftwerksprozesse mit Erdgas-Leichtoelfeuerung verglichen: Konventioneller Dampfprozess, Dampfprozess mit Vorschaltgasturbine, Gasturbinenprozess mit ND-Abhitzekessel und Kombianlage. Die Industriegasturbinen zwischen 10 und 25 MW werden gegenuebergestellt und typische Kessel und Industrieturbinen vorgestellt. Abschliessend werden ...
MRT criteria have been developed to distinguish between tumour and implant material following examination of 50 patients who had transsphenoidal hypophysectomies for tumours. Judgements were based on the postoperative hormonal status and the operation notes. Following contrast injection of Gd-DTPA and using T[sub 1] weighted spin-echo sequences, implant material appeared as sandwich-like, linear or circular structures. Residual recurrent tumour produced homogenous or non-homogenous aspects without marginal enhancement in 84% of cases. Postoperative displacement of the infundibulum to the opposite side was observed in 73% of patients with tumour remnants. Sensitivity of MRT was 70%, specificity 95%. There was a positive predictive value of 94% and a negative predictive value of 72% with an accuracy of 81%. This provides assistance in differentiating between tumour remnants and implant material. MRT is recommended as a method of examination for hypophyseal tumours to evaluate the success ...
The results of these investigations can be summarised as follows: At simulated operating stress most naturally occuring faults in welded- and cast iron parts develop cracks and can be assessed for reliability under fatigue-,creep- and creep fatigue behaviour according to the laws of fracture mechanics. The empirically determined correlation between the real fault size and the ultrasonic inspection results (height of echo, echo dynamics, sound weakening) lead to better assessment of real fault extension in turbine components. It is very important to adapt the method of inspection and assessment to the type of possible fault.(orig.) [German] Die bei diesen Untersuchungen ermittelten Ergebnisse lassen sich wie folgt zusammenfassen: - Die Mehrzahl der untersuchten natuerlichen Fehlstellen in den Schmiede- und Gussstuecken verhalten sich unter den simulierten Betriebsbeanspruchungen rissartig und sind damit mittels den bruchmechanischen Gesetzen in ihrem Rissfortschrittsverhalten unter ...
Industrial companies are being forced by increasingly restrictive environmental legislation to implement power station technology which is environmentally compatible and which conserves scarce resources. Gas and steam turbine power stations have been causing a sensation in this field for some time. This article gives an introduction to gas and steam turbine power stations in the 4 MW to 30 MW size range. The designs of the plants described here not only provide for electricity generation by gas and steam turbines however, but also designs specific to particular companies for process steam and district heating supply. (orig.) [Deutsch] Durch immer restriktivere Umweltschutzgesetze werden die Industrieunternehmen zu einer umwelt- und ressourcenschonenden Kraftwerkstechnik gedraengt. Auf diesem Gebiet sorgen nun seit geraumer Zeit GuD-Kraftwerke fuer Furore. In diesem Beitrag werden GuD-Kraftwerke in einer Groessenordnung zwischen 4 MW und 30 MW vorgestellt. Die ...
This paper provides some results of the research works at low pressure components of steam turbines and some construction solutions resulting in a modernisation. The problems of turbine phases for the transonic flow are analysed with respect to reducing profile and margin losses. The origin and flow of wet steam and its influence on corrosion and erosion is investigated. Inlet and outlet casing of the flow channels and transfer diffuser between second last and last phase are mentioned. (orig.) [Deutsch] Im Beitrag werden einige Ergebnisse der Forschung der Teile von ND-Teilen der Dampfturbinen angegeben, und werden irgendeine Konstruktionsloesungen, die fuer ihre Modernisierung guenstig sind, beschrieben. Kurz wird die Problematik der Turbinenstufen fuer die transsonische Stroemung analysiert, mit Hinsicht auf die Erniederung der Profil- und Randverluste. Weiter ist die Aufmerksamkeit der Entstehung und Stroemung des Nassdampfes im Zusammenhang mit dem Phaenomen der Korrosion und ...
Tribological performance of alumina and silicon carbide ceramics as well as of the hardened steel 100Cr6 for reference was studied during reciprocating sliding and cavitation erosion in isooctane as substitute of gasoline and in distilled water. It was the aim to characterize effects of surface finish of the specimens and the liquid media on friction, resistance to sliding wear and cavitation erosion. Sliding wear tests were run on the self-mated ceramics and ceramic/steel pairs under conditions of boundary lubrication using a laboratory tribometer with cylinder-on-plate geometry. Vibratory cavitation erosion tests were conducted according to ASTM G 32-92. High initial surface roughness of coarse ground specimens led to a distinct running-in period during sliding contact with a transition from high to low values of friction coefficient and wear intensity. Incubation time was reduced with increasing surface roughness in the cavitation tests. Depending on the materials investigated, the ...
Purpose: In an experimental study, the correlation between the trabecular bone density of the different regions of the proximal femur and the fracture load in the setting of femoral neck fractures was examined. Methods: The bone mineral density 41 random proximal human femora was estimated by single-energy quanitative CT (SE-QCT). The trabecular bone density was measured at the greatest possible extracortical volume at midcapital, midneck and intertrochanteric level and in the 1 cm{sup 3} volumes of the centres of these regions in a standardised 10 mm thick slice in the middle of the femoral neck axis (in mg/ml Ca-hydroxyl apatite). The proximal femora were then isolated and mounted on a compression/bending device under two-legged stand conditions and loaded up to the point when a femoral neck fracture occurred. Results: Statistical analysis revealed a linear correlation between the trabecular bone density and the fracture load for the greater regions, with the highest value in the ...
Materials and methods: 12 patients with 22 coronary bypass grafts underwent intraoperative flow quantification using the transit time ultrasound method. These values were compared to postoperative MR phase shift measurements. Flow measurements were performed preoperatively in 28 coronary arteries of 20 patients. For flow measurement, we used a velocity-encoded k-space segmented gradient echo sequence with a temporal resolution of 110 or 125 ms, respectively. 6-8 pase shift images could be acquired during one cardiac cycle. Results: There was a significant correlation between intraoperative and flow measurements using velocity-encoded MR imaging (r=0.76, p<0.0001, t-test). Flow volumes determined by MR imaging were systematically larger than those determined by the transit time ultrasound method. Mean flow in coronary arteries was reduced in severely stenosed vessels (>70%) compared to normal vessels. Intra- and interobserver variability were 10.5 and 15% (coronary bypass ...
Biosorption behaviour of and toxic effects of heavy metals in submersed and immobilised microorganisms was studied in batches and in continuous processes in an airlift-recycle reactor. Nickel, cadmium, and zinc were used as heavy metals. (orig./VHE) [Deutsch] Am Beispiel einer Naphthalin-2-sulfonsaeure-abbauenden Kultur wurde das Biosorptionsverhalten und die toxische Wirkung von Schwermetallen auf submerse und immobilisierte Mikroorganismen im Batch-Ansatz und im kontinuierlichen Betrieb in einem Airlift-Schlaufenreaktor untersucht. Als Schwermetalle wurden Nickel, Cadmium und Zink eingesetzt. (orig./VHE)
The present paper describes the application of the commercial CFD-code FLUENT 6.1 to the numerical simulation of the flow field in a high specific speed radial fan. Two-dimensional as well as three-dimensional computations are performed using the steady 'Frozen-Rotor method' as well as the unsteady 'Sliding-Mesh method'. The predicted performance curves of the radial fan are compared with the results obtained from measurements on a test stand. Due to the relatively low computation times, the 'Frozen-Rotor method' can be used routinely for design purposes. The results of this approach can be improved if the leakage flow through the gap between the inlet nozzle and the impeller is taken into account. (orig.)
The energy cost of compressors accounts for up to 90% of the total cost. Oil-free compressors could reduce the cost almost by half, i.e. annual savings of 112,500 DM would be achievable. [German] Ueber die Gesamtlaufzeit betrachtet, machen die Energiekosten bei Verdichtern bis zu 90% der Gesamtkosten aus. Deshalb muss bei der Auswahl von Kompressoren dem Energieverbrauch besondere Aufmerksamkeit geschenkt werden. Mit oelfreien Kolbenkompressoren liessen sich in einem speziellen Fall die Kosten fast halbieren, was jaehrlichen Einsparungen von 112 500 DM entspricht. (orig.)
Zusammenfassung Die Festigkeitshypothesen und Flie?fl?chen aus den klassischen Kursen der Mechanik (die Normalspannungshypothese, die Modelle nach von Mises und Tresca) reichen oft nicht aus, das tats?chliche Verhalten von Bauteilen unter Belastung zu erfassen. Deshalb werden in der Literatur weitere Modelle mit einem oder mehreren Parametern vorgeschlagen. Diese Modelle beschr?nken allerdings die Geometrien der zul?ssigen Formen der Fl?chen im Spannungsraum. In dieser Arbeit wird ein auf die Zugspannung normiertes Druck-Torsion-Diagramm vorgestellt, in dem sich die Modelle inkompressiblen Materialverhaltens miteinander vergleichen lassen. Mit diesem Diagramm wird der Begriff der Symmetrie der Fl?che in der ?-Ebene verdeutlicht. Die konvexen Fl?chen inkompressiblen Materialverhaltens sind ...
The 'KUPOLOPT' joint research project has as its target the economic and ecological optimization of cupola furnaces in foundries. The use of natural gas/oxygen burners during foundry operation is being studied on Fritz Winter Eisengiesserei GmbH and Co. KG's cupola furnace with the objective of enhancing melting rate, reducing emissions and permitting re-utilization of foundry and other particulates. This work is also intended to improve the cupola-furnace process in economic terms, in order to enhance its competitiveness. This article presents the results of the first project phase, which served to investigate the natural gas/oxygen burner as an external supplier of energy. (orig.)
Pregraduate medical curricula are currently undergoing a reform process that is moving away from a traditional discipline-related structure and towards problem-based integrated forms of teaching. Imaging sciences, with their inherently technical advances, are specifically influenced by the effects of paradigm shifts in medical education. The teaching of diagnostic radiology should be based on the definition of three core competencies: in vivo visualization of normal and abnormal morphology and function, diagnostic reasoning, and interventional treatment. On the basis of these goals, adequate teaching methods and e-learning tools should be implemented by focusing on case-based teaching. Teaching materials used in the fields of normal anatomy, pathology, and clinical diagnosis may help diagnostic radiology to play a central role in modern pregraduate curricula. (orig.)
High temperature components of power plants are in many cases subjected to variable loading conditions such as cyclic creep or strain cycling. Therefore the cyclic behaviour of important heat resistant steels has been investigated under stress control and to a smaller extent under strain control. The behaviour under cyclic creep rupture conditions was determined in long term experiments covering a wide range of loading conditions. This behaviour can be described with the modified life fraction rule and a factor concept of relative life for single stage cycles and additionally with a multistep hypothesis for multi-stage cycles. The description can be adapted to estimate the life consumption under service type random conditions. The strain cycling behaviour was investigated in regard to the conditions of the heated surface of large components. To simulate this type of loading and to generate long term creep fatigue data, a service type strain cycle was developed. Anisothermal and ...
Trapezblechstege im Bruckenbau kommen trotz der groen Vorteile, die diese Bauweise bietet, in Deutschland bisher nur an einem Pilotprojekt zur Anwendung. Durch die charakteristischen Eigenschaften des Trapezbleches entstehen konstruktive und wirtschaftliche Vorteile gegenuber herkommlichen Bruckenbauweisen. Allerdings lassen die aktuell gultigen Regelwerke aufgrund fehlender Kenntnis zum Tragverhalten und mangelnder Erfahrung keine wirtschaftliche Ausbildung zu. Dies zeigt sich am Beispiel des Pilotprojekts. Die Ausbildung der Verbundfuge wurde hier nur sehr unbefriedigend gelost und verdeutlicht somit die Notwendigkeit einfacher und praktikabler Verbindungsmoglichkeiten. Am Institut fur Leichtbau Entwerfen und Konstruieren der Universitat Stuttgart wurde in Zusammenarbeit mit dem Institut...
Technical innovations such as the availability of movable patient platforms and the introduction of 32-channel systems have made whole-body MRI for tumor staging feasible. In addition, the development of dual-modality PET/CT systems offers the opportunity to perform anatometabolic tumor staging with whole-body coverage in a single session. Based on an increase in patient survival when applying a stage-adapted therapy in different malignant diseases the relevant question relates to the accuracies of whole-body MRI and whole-body PET/CT for TNM staging. This review article addresses whole-body tumor staging with MRI and FDG-PET/CT with special emphasis on diagnostic accuracies for staging different malignant diseases. (orig.) [German] Technische Neuerungen, wie die Verfuegbarkeit beweglicher Tischaufsaetze oder die Einfuehrung von 32-Kanal-Systemen, haben die Ganzkoerperbildgebung mit der MRT ermoeglicht. Die Entwicklung kombinierter PET/CT-Systeme bereitet den Weg fuer eine simultane ...
In coke-oven operations flue-gas valves are used to switch the regenerator function from rich gas firing to lean gas firing. Compared with the simple geometry of the other parts of the flow path, which comprise flues and regenerators, the narrow and winding passages of the flue-gas valves give rise to relatively high losses in pressure. Without the construction of high (and therefore expensive) chimneys, this means that operating problems may well arise due the inadequate suction capacity. The project focused on the theoretical and experimental analysis of a coke-oven flue-gas valve. The primary aim was to reduce the pressure drop through the valve without modifying its external geomerty. The internal flow characteristics created by different valve geometries under a variety of operating conditions were simulated using the commercial CFD code Fluent/UNS, which provided velocity and pressure distributions. A half-scale model valve was constructed in order to characterise the internal ...
Early in 1988 RWE decided to overhaul the power station at Goldenberg. This was necessary due to the age of the plant, the obligation to supply heat and process steam and recent amendments of environmental legislation. After analysing demands and needs one developed a plant concept with a 290 t/h and a 400 t/h steam generator. Due to lack of space the decision was made in favour of a circulating atmospheric fluidised bed combustion instead of steam generators with pulverised lignite combustion as these steam generators take up much more space due to the legally required desulphurisation plants for gaseous emissions. Apart from generating steam RWE wishes to gain experience with this combustion technology and test it for suitability and use in large-scale plant. (orig./KO) [Deutsch] Aufgrund des fortgeschrittenen Alters, der aktuellen Umweltschutzgesetzgebung sowie bestehender Versorgungsverpflichtungen fuer Waerme und Prozessdampf wurde Anfang 1988 von der RWE Energie AG in Essen die ...
In order for fuel cells to be successful, a full-scale hydrogen infastructure is required. The HyTra concept is presented here (HYdrogen TRAnsform, Transfer and TRAnsport) involves combined production, storage and supply of hydrogen in a transportable trailer, i.e. it is both a hydrogen production unit and a mobile filling station. The trailer can be transported to the selected site, where it will produce gaseous hydrogen from electricity and water by electrolysis. A compressor pumps the gas into an internal pressure tank and compresses it to filling pressure. Filling takes place by the overflow principle via a flexible high-pressure line with a standardised H{sub 2} filling unit. (orig.) [German] Um die Marktdurchdringung der Brennstoffzellentechnik gewaehrleisten zu koennen, muss eine flaechendeckende Wasserstoffinfrastruktur aufgebaut werden. Das neue HyTra-Konzept (HYdrogen TRAnsform, TRAnsfer and TRAnsport) beruht auf der Kombination von Wasserstoff-Erzeugung, -Speicherung und ...
An extensive set of benchmark measurement of PDDs and beam profiles was performed in a heterogeneous layer phantom, including a lung equivalent heterogeneity, by means of several detectors and compared against the predicted dose values by different calculation algorithms in two treatment planning systems. PDDs were measured with TLDs, plane parallel and cylindrical ionization chambers and beam profiles with films. Additionally, Monte Carlo simulations by meansof the PENELOPE code were performed. Four different field sizes (10x10, 5x5, 2x2, and1x1 cm"2) and two lung equivalent materials (CIRS, #rho#_e"w=0.195 and St. Bartholomew Hospital, London, #rho#_e"w=0.244-0.322) were studied. The performance of four correction-based algorithms and one based on convolution-superposition was analyzed. The correction-based algorithms were the Batho, the Modified Batho, and the Equivalent TAR implemented in the Cadplan (Varian) treatment planning system and the TMS Pencil Beam ...
Objective: To characterize the protocols with low-dose radiation in survey CT scans for localization. Methods: Eighty standard adult patients, head and body phantoms were recruited. Default protocols provided by operator's manual setting were that all the tube voltage for head, chest, abdomen and lumbar was 120 kV; the tube currents were 20,10,20 and 40 mA, respectively. Values of kV and mA in the low-dose experiments were optimized according to the device options. For chest and abdomen, the tube position were compared between default (0 degree) and 180 degree. Phantoms were scanned with above protocols, and the radiation doses were measured respectively. Paired t-test were used for comparisons of standard deviation in CT value, noise and exposure surface dose (ESD) between group with default protocols and group with optimized protocols. Results: The optimized protocols in low-dose CT survey scans were 80 kV, 10 mA for head, 80 kV, 10 mA for ...
With the advent of intensity-modulated radiation therapy (IMRT), the inclusion of heterogeneity corrections is further complicated by the conformal delivery of many small beams forming steep dose gradients. Radiation treatment planning has evolved to take into account even small changes in tissue density so that the dose to tumor can be further optimized. However, different treatment planning systems incorporate different heterogeneity correction algorithms, and it is unclear whether any of these algorithms are superior to others in terms of accurately predicting delivered radiation doses relative to measurement in a clinical setting. The purpose of this study was to determine the accuracy of heterogeneity dose calculations from two widely used IMRT treatment planning systems (Pinnacle and Corvus) against measurement. These two systems handle heterogeneity dose corrections by means of a collapsed-cone convolution superposition algorithm and a finite-size pencil-beam algorithm with ...
MR images of steady and pulsatile disturbed flow, obtained with use of flow-compensated spin-echo (SE) and cine pulse sequences, revealed excellent flow visualization in three dimensions. Phantoms, built from molds of actual blood vessels, reproduced laminar, disturbed, or turbulent flow. Video recording (VR), performed under conditions equivalent to those of the MR experiments, showed separation zones identical to those seen on SE images. Pulsatile flow studies showed complex patterns of vortical flow on cine images and VR. Varying pulse sequence details changed contrast but not flow patterns. The validation of MR observations by VR has implications for clinical cine imaging and low abnormal signals observed on MR angiograms.
A computer method that calculates tracheal cross-sectional area by compensating for partial volume averaging was developed and validated in a study with phantoms. The program was then used to determine the tracheal cross-sectional area of 30 normal children who ranged in age from four months to 18 years. CT-derived cross sections were correlated with age, height, weight, and body-surface area, and they were compared with findings of published clinical and post-mortem studies. CT cross-sectional areas ranged from 20 to 275 mm/sup 2/, varied by as much as 22% at the three different tracheal levels studied, and appeared to correlate most closely with body height. CT-derived tracheal cross-sectional areas are quite similar to those in published reports of postmortem and clinical studies. Measurements of tracheal cross section by CT may prove useful in quantitating tracheal compromise by intrinsic or extrinsic causes.
The studies using phantoms confirmed that the reduction of electron beam energy and minimization of X-ray contamination could be achieved when electron beam was interposed by an acrylic plate placed 20 cm anterior to a patient. Four patients of mycosis fungoides were treated with 8 MeV electron beam of a linear accelerator at UOEH Hospital from October 1981 to December 1986. Two of them were treated with this technique by placing 2 cm thick acrylic plate anterior to the patients and satisfactory results were obtained. Cutaneous lesions subsided remarkably with the dosage of 2000 cGy given in 2 months. Leucopenia due to bone marrow suppression was mild and the patients tolerated the treatment well.
The studies using phantoms confirmed that the reduction of electron beam energy and minimization of X-ray contamination could be achieved when electron beam was interposed by an acrylic plate placed 20 cm anterior to a patient. Four patients of mycosis fungoides were treated with 8 MeV electron beam of a linear accelerator at UOEH Hospital from October 1981 to December 1986. Two of them were treated with this technique by placing 2 cm thick acrylic plate anterior to the patients and satisfactory results were obtained. Cutaneous lesions subsided remarkably with the dosage of 2000 cGy given in 2 months. Leucopenia due to bone marrow suppression was mild and the patients tolerated the treatment well. (author).
Objectives Clinical PET/MR requires the use of patient positioning aids to immobilize and support patients for the duration of the combined examination. Ancillary immobilization devices contribute to overall attenuation of the PET signal, but are not detected with conventional MR sequences and, hence, are ignored in standard MR-based attenuation correction (MR-AC). We report on the quantitative effect of not accounting for the attenuation of patient positioning aids in combined PET/MR imaging. Methods We used phantom and patient data acquired with positioning aids on a PET/CT scanner (Biograph 16, HI-REZ) to mimic PET/MR imaging conditions. Reference CT-based attenuation maps were generated from measured (original) CT transmission images (origCT-AC). We also created MR-like attenuation map...
By measuring organ doses with TLD at an Alderson-Rando-phantom it was tested to evaluate the somatic risk for mammographies. Similarly as the genetic risk can be expressed by the genetic significant dose, the somatic risk can be expressed by the somatic significant dose index. The measurement results of the mammography show a large deviation of almost one power of ten with dependence of the chosen technique. In conventional xeroradiography and recording technique with foilless film the somatic radiation risk is the highest. By using amplifying foils in combination with high-sensitive films it is relatively small. Unfortunately the magnitude of the somatic risk in the different mammography techniques is in the ratio reciprocal to the corresponding image quality. At the time being the most favourable technique is mammography with a soft rastering method, although the xeromammography with additional high aluminium-filtering is a further alternative with respect to ...
The somatic and genetic radiation exposure of patients undergoing Digital Subtraction Angiography (DSA) and traditional Film Arteriography (FA) of cranial, cervical, thoracic and abdominal vascular territories are compared. The radiation doses absorbed within the critical organs - red bone marrow, lung, thyroid gland and female breast - and in the gonads were measured using an anthropomorphic Alderson phantom. A Somatic Dose Index was calculated in order to estimate the somatic radiation risk. The somatic radiation exposure depends upon the location of the critical organs with respect to the entrance site of the x-ray beam, and can be reduced by an appropriate choice of the angiographic projection. Under this condition, the radiation exposure of the patient during DSA can be lower than during FA. For renal DSA an a.p. projection, the use of an abdominal compression device and careful caudal shielding of the field are advocated. (orig.).
Sex differences in pain are frequently reported in the literature. However, less is known about possible sex differences in the experience of pain secondary to a disability. The current study explored these issues in persons with limb loss (n = 335, 72% men) who were recruited as part of a postal survey. Participants provided ratings of phantom limb pain (PLP), residual limb pain (RLP), and general pain intensity. Participants also completed measures of pain-related interference, catastrophizing, coping, and beliefs. Results indicated that a greater proportion of males than females (86% vs 77%, respectively) reported the presence of PLP; however, this difference was no longer prominent when cause of limb loss was controlled. No sex differences were found in the presence of RLP, or in avera...
Using phantoms of children simulating a child of 6 months of age and another one aged 6 years, the authors measured the amount of radioexposure of the lens of the eye, the thyroid and of the gonads. The two computer tomographs Somatom SF and Tomoscan 300 under examination, produced radiodoses of comparable magnitudes. Both devices allow additional examination techniques of particularly high economy. It was found that in cranial CT the exposure of the lens to radiation is generally below 1 R if the orbitae are not situated in the plane of section. If a distance of 2-3 cm is maintained from the orbitae, the dose remains below 0.5 R. Protecting the gonads is meaningful in a 6-year-old boy, whereas covering-up of the thyroid reduced the dose only slightly.
Objective: To investigate the X-ray radiation dose patients dealt with the hepatic intervention. Methods: Thermoluminescence and tissue-equivalent anthropomorphic phantom were used to measure the X-ray radiation dose in patients dealt with the hepatic intervention in 85 patients. Results: The peak skin dose in the patients who accepted hepatic intervention was from 179.95 to 1759.00 mGy, effective dose approached 29.22 mSv (male), 29.27 mSv (female). Conclusion: Hepatic intervention is now regarded as an important therapeutic method for liver cancer. However, the patients were exposed to too much X-ray radiation during interventional procedures. Some more effective protection should be taken to decrease the X-ray radiation dose accepted by patients. (authors)
Purpose: To evaluate a simple method for quantification of focal activity in bone scintigraphy (BS). Material and methods: The gamma camera was calibrated using a phantom. Quantitative bone scintigraphy (QBS) was performed on 11 men recently diagnosed with prostate cancer (PCa), for whom routine BS showed involvement of the skeleton. Following endocrine therapy for 4 to 8 months, a second QBS was performed. Changes in QBS values were then compared to changes in serum levels of prostate-specific antigen (PSA). Results: PSA response indicating regression of PCa was accompanied by a decrease in the QBS value in 8 of the 11 patients. The overall mean error of the QBS values was 15%. conclusion: QBS according to this method is a relatively simple procedure that might contribute to objective evaluation of therapeutic effects in skeletal metastases, although its validity must be tested in a larger clinical material.
Purpose: To evaluate a simple method for quantification of focal activity in bone scintigraphy (BS). Material and methods: The gamma camera was calibrated using a phantom. Quantitative bone scintigraphy (QBS) was performed on 11 men recently diagnosed with prostate cancer (PCa), for whom routine BS showed involvement of the skeleton. Following endocrine therapy for 4 to 8 months, a second QBS was performed. Changes in QBS values were then compared to changes in serum levels of prostate-specific antigen (PSA). Results: PSA response indicating regression of PCa was accompanied by a decrease in the QBS value in 8 of the 11 patients. The overall mean error of the QBS values was 15%. conclusion: QBS according to this method is a relatively simple procedure that might contribute to objective evaluation of therapeutic effects in skeletal metastases, although its validity must be tested in a larger clinical material
A Quantitative Computed Tomography (QCT) method, simplifying the well-known technique proposed by Genant (1982) and applied to a standard third generation whole body CT scanner is described. This technique was applied in the measurement of the trabecular bone which has high sensitivity for metabolic changes. The BMC (Bone Mineral Content) measured in different groups of subjects (healthy postmenopausal patients versus women with postmenopausal osteoporosis) showed a highly significant difference (p<0.001). The precision of repositioning (coefficient of variation 1.8% to 2.3%, obtained in healty male patients) and the good, linear relationship computed from the phantom values, minimize measurement errors. Since this method is quickly applied and involves low-dose radiation-exposure, it could be introduced in the clinical study of metabolic bone diseases.
It was developed a new formulation of macro aggregates of Samarium 153 ({sup 153} Sm-MH) for the arthropaties treatment. The radio pharmaceutic was prepared by reaction of Samarium 153 chloride (SmCl{sub 3}) in aqueous environment with sodium boron hydride in NaOH 0.5 N. The microscopic analysis shown that the particles have an average size of 4% m (range 1-14 {mu} m). The velocity of sedimentation was 0.008 cm/min with high stability in vitro in human serum. The biological studies in healthy rabbits, shown that the complex is retained inside the articulation still eight days after of the administration of the radiopharmaceutical. Likewise, it is presented the data of absorbed dose in the different target organs, which was determined by thermoluminescent dosimetry (TLD) through the use of a REMCAL phantom (radiation equivalent manikin calibration). (Author)
Although previous research suggests that preamputation pain is a risk factor for pain after amputation, little is known about the association between acute postsurgical pain and chronic amputation-related pain. The current prospective study examined the associations of preamputation pain and acute postamputation pain with chronic amputation-related pain. The sample consisted of patients with lower limb amputation (N = 57) who provided both preamputation and postamputation data during a 2-year study period. Preamputation pain intensity and duration were assessed before amputation; acute phantom limb pain (PLP) and residual limb pain (RLP) intensity were assessed on postsurgical days 4 and 5. Acute PLP intensity was the only significant independent predictor of chronic PLP intensity at 6 and...
Portal localization images for high-energy electron beam therapy are necessary to confirm the treatment field by comparing them with a simulation image obtained before treatment or portal verification images after treatment. In this study, portal localization images were acquired using the computed radiography (CR) system and bremsstrahlung X-rays generated in the electron beam irradiations. All images obtained with phantom and the irradiations of in the electron energy of 8, 10, 12 and 15 MeV were feasible for clinical use. The CR system used in this study included general diagnostic imaging cassette and storage phosphor plate, but none of other special devices. The system can usually supply portal localization images, which maintains the quality assurance of high-energy electron beam therapy. (author)
The basic relationships of the convolution/superposition dose calculation technique are reviewed, and a modelling technique that can be used for obtaining a satisfactory beam model for a commercially available convolution/superposition-based treatment planning system is described. A fluence energy spectrum for a Co-60 treatment machine obtained from a Monte Carlo simulation was used for modelling the fluence spectrum for a Rokus M machine. In order to achieve this model we measured the depth dose distribution and the dose profiles with a Wellhofer dosimetry system. The primary fluence was iteratively modelled by comparing the computed depth dose curves and beam profiles with the depth dose curves and crossbeam profiles measured in a water phantom. The objective of beam modelling is to build a model of the primary fluence that the patient is exposed to, which can then be used for the calculation of the dose deposited in the patient. (authors)
A photoacoustic (PA) imaging system based on an ultrasonic Fresnel zone plate (FZP) transducer is developed for the purpose of imaging biological tissue. This FZP transducer has a two-zone negative zone plate piezoelectric material pattern, and an optical fibre is integrated with the transducer on the symmetric axis of the zone plates to deliver laser pulses to the sample. The focal characteristic of the FZP transducer is analysed by theoretical prediction and experimental measurement, and the measured results are in good agreement with the predicted results. The limited-field back-projection deconvolution algorithm combined with the coherence-factor weighting technique is used to reconstruct the optical absorption distribution. The experiments were performed with phantoms and the blood vessels of chicken embryo chorioallantoic membrane. The results demonstrate that PA imaging using the FZP transducer has the ability to image biological tissue and has potential ...
When evaluating the risks of oncogenesis and cancer mortality following exposure to the radiations of the atomic bombs (A-bombs), the medical X-ray doses received by the A-bomb survivors must also be estimated and considered. Using a human phantom, dosimetry was performed to estimate the X-ray doses received by A-bomb survivors during medical examinations at the Radiation Effects Foundation (RERF) as part of the long-term follow-up on the Adult Health Study (AHS). These examinations have been estimated to represent nearly 45% of the survivors' cumulative medical irradiation dose. Doses to the salivary glands, thyroid gland, lung, breast, stomach and colon were measured using thermoluminescent dosemeters. The results, which are reported here, will aid in estimating organ doses received by individual AHS participants. (Author).
When evaluating the risks of oncogenesis and cancer mortality following exposure to the radiations of the atomic bombs (A-bombs), the medical X-ray doses received by the A-bomb survivors must also be estimated and considered. Using a human phantom, dosimetry was performed to estimate the X-ray doses received by A-bomb survivors during medical examinations at the Radiation Effects Foundation (RERF) as part of the long-term follow-up on the Adult Health Study (AHS). These examinations have been estimated to represent nearly 45% of the survivors' cumulative medical irradiation dose. Doses to the salivary glands, thyroid gland, lung, breast, stomach and colon were measured using thermoluminescent dosemeters. The results, which are reported here, will aid in estimating organ doses received by individual AHS participants. (Author).
Since the fluoroscopic image during nasoenteral tube placements is used for guidance and not for diagnosis, a lower contrast image with increased quantum mottle can be easily tolerated. The three methods to reduce the radiation dose rate investigated consisted of removing camera from the image intensifier output phosphor, and setting the fluoroscopic mA to the minimum value so that the kVp could be maximized. Fluoroscopic frozen video frames of a clinical tube insertion comparing the images with and without the dose-saving techniques are presented. Measurements of the radiation dose rates using a Plexiglas phantom show that the dose for patient and staff during fluoroscopic-guided nasoenteral tube placements can be reduced by over a factor of 10 without significantly adversely affecting the actual placement procedure. (author).
During fluoroscopy the examiner is usually protected by a radiation-reducing body shield, leaving the thyroid unprotected. The fact that the thyroid is located in a region of the neck usually covered by the shirt collar led to the idea of designing a tie with lead core, providing easy and ''decorative'' reduction of the radiation dose. Sonographic examinations were carried out in 20 volunteers (10 men, 10 women) to determine the size of the gland and its coverage by such a tie. The reduction of the surface and organ dose was assessed using film dosimetry with scattered radiation, the body of the examiner being simulated by an Alderson phantom. On average 88% of the thyroid gland surface area was covered. Surface dose was reduced to 1%, and organ dose to 10% of the value without the protection tie. (Author).
During fluoroscopy the examiner is usually protected by a radiation-reducing body shield, leaving the thyroid unprotected. The fact that the thyroid is located in a region of the neck usually covered by the shirt collar led to the idea of designing a tie with lead core, providing easy and ''decorative'' reduction of the radiation dose. Sonographic examinations were carried out in 20 volunteers (10 men, 10 women) to determine the size of the gland and its coverage by such a tie. The reduction of the surface and organ dose was assessed using film dosimetry with scattered radiation, the body of the examiner being simulated by an Alderson phantom. On average 88% of the thyroid gland surface area was covered. Surface dose was reduced to 1%, and organ dose to 10% of the value without the protection tie. (Author).
Fuji computed radiography (FCR) utilizing imaging plates stimulated by a scanning lazer has been developed in Japan and come to be widely available in diagnostic radiology. This system is advantageous because many processed images can be obtained with a single exposure. However, no reports have been published on the exact conditions necessary under which the FCR image processing method will produce improved visibility of pulmonary abnormal shadows on chest radiographs. In this report, chest FCR images obtained from 50 patients were analyzed, and the best practical image processing conditions were determined for each pathological state. Fundamental analysis was also performed for spatial and contrast resolution with FUNK chart and Burger's phantom using various thickness of acryl plate. Ninety processing images per exposure were analyzed, and the best practical conditions were determined. (author).
Fuji computed radiography (FCR) utilizing imaging plates stimulated by a scanning lazer has been developed in Japan and come to be widely available in diagnostic radiology. This system is advantageous because many processed images can be obtained with a single exposure. However, no reports have been published on the exact conditions necessary under which the FCR image processing method will produce improved visibility of pulmonary abnormal shadows on chest radiographs. In this report, chest FCR images obtained from 50 patients were analyzed, and the best practical image processing conditions were determined for each pathological state. Fundamental analysis was also performed for spatial and contrast resolution with FUNK chart and Burger's phantom using various thickness of acryl plate. Ninety processing images per exposure were analyzed, and the best practical conditions were determined. (author).
Psychological distress and postamputation pain were investigated in a sample of 582 males with long-term limb amputations (mean time since amputation 639.3 months, standard deviation 166.1; range 240-784 months). Prevalence of significant depressive symptoms (Hospital Anxiety and Depression Scale [HADS]-D score?8) was 32.0%, and 34.0% of respondents met the screening criterion for clinical anxiety (HADS-A score?8). Nearly one quarter (24.6%) of respondents reported significant post-traumatic psychological stress symptoms (Impact of Event Scale scores?35). In total, 87.8% experienced either phantom or residual limb pain. Affective distress scores differed according to the respondents' type of pain experience. Respondents who experienced residual limb pain reported significantly hig...
Abstract A method was developed to quantify the effect of scanner instability on functional MRI data by comparing the instability noise to endogenous noise present when scanning a human. The instability noise was computed from agar phantom data collected with two flip angles, allowing for a separation of the instability from the background noise. This method was used on human data collected at four 3 T scanners, allowing the physiological noise level to be extracted from the data. In a -well-operating- scanner, the instability noise is generally less than 10% of physiological noise in white matter and only about 2% of physiological noise in cortex. This indicates that instability in a well-operating scanner adds very little noise to functional MRI results. This new method allows researcher...
For charged particle irradiations, the response of an imaging plate (IP) changes around the Bragg peak. Therefore, an appropriate compensation is necessary for the evaluation of dose distribution formed by charged particles such as protons. In this paper, the response of IPs to clinical proton beams is investigated. An experimentally-obtained depth-dose distribution (an ordinary Bragg curve) by a silicon semiconductor detector (SSD) is employed to evaluate the compensation factors as a function of proton penetrating depth, i.e. residual range. A typical dose distribution in a water phantom formed by an L-shaped bolus is measured by IPs and corrected by using the information of those compensation factors; the residual proton range is successfully calculated by the pencil beam algorithm at an arbitrary point. The results show a good agreement with the measurements by the SSD within the rms error of 3.0%.
For a given linac design, the dosimetric characteristics of a photon beam are determined uniquely by the energy and radial distributions of the electron beam striking the x-ray target. However, in the usual commissioning of a beam from measured data, a large number of variables can be independently tuned, making it difficult to derive a unique and self-consistent beam model. For example, the measured dosimetric penumbra in water may be attributed in various proportions to the lateral secondary electron range, the focal spot size and the transmission through the tips of a non-divergent collimator; the head-scatter component in the tails of the transverse profiles may not be easy to resolve from phantom scatter and head leakage; and the head-scatter tails corresponding to a certain extra-focal source model may not agree self-consistently with in-air output factors measured on the central axis. To reduce the number of adjustable variables in beam modelling, we replace ...
The focus of this study is to validate whether the sensitivity of dose distribution following the interface of different media can be used to distinguish between small variations of photon energy spectra in the context of the convolution/superposition algorithm in the polyenergetic implementation (Philips Pinnacle"3, ADAC Laboratories, Milpitas, CA). Calculations were performed in homogeneous water and heterogeneous lung/water phantoms. Spectra were generated, in which the weights of the low-, medium- and high-energy components were adjusted sequentially. The heterogeneity correction factor CF_l_u_n_g, the D_2_0/D_1_0 ratio for homogeneous water and logarithmic derivative in buildup region LD_b_u_i_l_d_u_p were assessed for their relative ability to discriminate between different spectra for various field sizes. In accordance with another study (Charland et al 2004), the superior discrimination ability of the CF_l_u_n_g and LD_b_u_i_l_d_u_p tests over the ...
Conventional Radiography, Fuji Computed Radiography (FCR) hardcopy and CRT images were evaluated about the detectability of pulmonary nodule using the chest phantom. Conventional and digitized chest radiographs (FCR) were used, including 45 normal cases and 45 abnormal cases with a variety pulmonary nodule. Observer performance tests were conducted to compare the effects on diagnostic accuracy of Conventional Radiography, FCR hardcopy and CRT images, and diagnostic accuracy was determined with receiver operating characteristic (ROC) analysis. ROC study was performed in which six radiologists were asked to locate nodule on three modalities. Two CRT monitors were used to observed CRT images. The left side CRT monitor was divided into two parts and displayed two images which were done as same image processing as FCR hardcopy. The right side CRT monitor was divided into four parts and displayed four images as a subsidiary diagnosis. The upper two images were displayed ...
Conventional Radiography, Fuji Computed Radiography (FCR) hardcopy and CRT images were evaluated about the detectability of pulmonary nodule using the chest phantom. Conventional and digitized chest radiographs (FCR) were used, including 45 normal cases and 45 abnormal cases with a variety pulmonary nodule. Observer performance tests were conducted to compare the effects on diagnostic accuracy of Conventional Radiography, FCR hardcopy and CRT images, and diagnostic accuracy was determined with receiver operating characteristic (ROC) analysis. ROC study was performed in which six radiologists were asked to locate nodule on three modalities. Two CRT monitors were used to observed CRT images. The left side CRT monitor was divided into two parts and displayed two images which were done as same image processing as FCR hardcopy. The right side CRT monitor was divided into four parts and displayed four images as a subsidiary diagnosis. The upper two images were displayed ...
The Anisotropic Analytical Algorithm (AAA) is a new pencil beam convolution/superposition algorithm proposed by Varian for photon dose calculations. The configuration of AAA depends on linear accelerator design and specifications. The purpose of this study was to investigate the accuracy of AAA for an Elekta SL25 linear accelerator for small fields and intensity modulated radiation therapy (IMRT) treatments in inhomogeneous media. The accuracy of AAA was evaluated in two studies. First, AAA was compared both with Monte Carlo (MC) and the measurements in an inhomogeneous phantom simulating lung equivalent tissues and bone ribs. The algorithm was tested under lateral electronic disequilibrium conditions, using small fields (2x2 cm"2). Good agreement was generally achieved for depth dose and profiles, with deviations generally below 3% in lung inhomogeneities and below 5% at interfaces. However, the effects of attenuation and scattering close to the bone ribs were not ...
Endogenous fluorescence provides morphological, spectral, and lifetime contrast that can indicate disease states in tissues. Previous studies have demonstrated that two-photon autofluorescence microscopy (2PAM) can be used for noninvasive, three-dimensional imaging of epithelial tissues down to approximately 150 ?m beneath the skin surface. We report ex-vivo 2PAM images of epithelial tissue from a human tongue biopsy down to 370 ?m below the surface. At greater than 320 ?m deep, the fluorescence generated outside the focal volume degrades the image contrast to below one. We demonstrate that these imaging depths can be reached with 160 mW of laser power (2-nJ per pulse) from a conventional 80-MHz repetition rate ultrafast laser oscillator. To better understand the maximum imaging depths that we can achieve in epithelial tissues, we studied image contrast as a function of depth in tissue phantoms with a range of relevant optical properties. The ...
The feasibility of using a multileaf collimator (MLC) for grid therapy is demonstrated in this study. Grids with the projected field openings of 10 mmx10 mm and 5 mmx5 mm were created using multiple MLC-shaped fields. The deposited doses were measured with films at different depths in a solid water phantom and compared to those of Cerrobend grid collimators of similar hole sizes and hole separations. At the depth of maximum dose (d_m_a_x), the valley-to-peak dose ratios of the MLC grids were found to be about 11% and 19% for the respective 10 mmx10 mm and 5 mmx5 mm grid openings, and those of the corresponding grid blocks were about 15% and 20%. To quantify the dose contributed by transmission in the blocked areas due to the limited leaf thickness, Monte Carlo simulations (based on convolution/superposition method) were performed to calculate the doses in the solid water phantom using an ideal MLC with no leakage and perfect divergence in both ...
Purpose: In this paper, we present an alternative to the originally proposed technique for the delivery of spatially fractionated radiation therapy (GRID) using multi-leaf collimator (MLC) shaped fields. We employ the MLC to deliver various pattern GRID treatments to large solid tumors and dosimetrically characterize the GRID fields. Methods and materials: The GRID fields were created with different open to blocked area ratios and with variable separation between the openings using a MLC. GRID designs were introduced into the Pinnacle"3 treatment planning system, and the dose was calculated in a water phantom. Ionization chamber and film measurements using both Kodak EDR2 and Gafchromic EBT film were performed in a SolidWater phantom to determine the relative output of each GRID design as well as its spatial dosimetric characteristics. Results: Agreement within 5.0% was observed between the Pinnacle"3 predicted dose distributions and the ...
A vessel phantom suitable for evaluation of spatial and contrast resolution of FCRDSA (Fuji Computed Radiography, digital subtraction angiography) has been developed and used for determining resolution. The effects of iodine concentration, low dose exposure, and acryl thickness on the resolution were evaluated in FCRDSA, and FCRDSA images were compared with film substraction with use of this phantom. It has been proven that limitation of resolution of FCRDSA was 5 % 1 mm and about 1/4 dose exposure compared with conventional film exposure was clinically acceptable. Dye dilution method was useful to determine a program of IVDSA with imaging plate. It has been proven that time to appearance and time to peak of time-concentration curve of dye dilution method closely correlate to time to appropriate image of DSA in the neck, the chest, and the abdomen. 106 cases of IVDSA and 130 cases of IADSA using FCR in Tohoku University Hospital from January ...
Using Monte Carlo simulation and the convolution/superposition algorithm, this work examines percent depth dose curves of the central axis in an acrylic phantom (20x20x20 cm"3) with variously sized air cavities (20x20x1.0, 20x20x2.0, 20x20x3.0, 20x20x4.0 and 20x20x4.95 cm"3 for study of longitudinal electron disequilibrium (ED) and 3.6x3.6x4.95, 4.5x4.5x4.95, 5.4x5.4x4.95 and 20x20x4.95 cm"3 for study of lateral ED). Radiochromic film samples are also measured to verify the Monte Carlo results. The Monte Carlo simulation is performed using OMEGA/BEAM and DOSXYZ codes, and the convolution/superposition calculation relies on an ADAC commercial treatment planning system. Underestimating the dose kernel expansion leads to overestimating the dose of what was found in the air cavity of ED using the convolution/superposition algorithm. Consequently, the dose in the rebuild-up region is influenced. The influenced region is on the acrylic phantom ...
The purpose of this study is to evaluate the accuracy of dose calculations by three algorithms. Depth dose, OPF (Output Factor) and dose profiles were measured in a heterogeneous phantom. These values were also calculated by three algorithms of the Batho power law (BPL), Equivalent-Tissue Air Ratio (ETAR) and Convolution superposition (CS). The data were obtained for 4, 6 and 10 MV photon beams with a linear accelerator (Varian 21EX). Field size ranged from 3 x 3 cm"2 to 10 x 10 cm"2. Dose profiles of beam penumbra were also measured by a 0.125 ml ionization chamber at the point of 8, 13 and 18 cm from the surface of the phantom at intervals of 1 mm. Differences between measured and calculated depth doses were within 2% in BPL and CS, but depth doses were overestimated in ETAR. OPFs were also overestimated with the error of more than 4% in ETAR. Absorbed dose calculated by CS were in agreement with the values measured by the ionization chamber. ...
A great deal of current research is directed to finding a way to minimize thermal injury in the esophagus during radiofrequency catheter ablation of the atrium. A recent clinical study employing a cooling intraesophageal balloon reported a reduction of the temperature in the esophageal lumen. However, it could not be determined whether the deeper muscular layer of the esophagus was cooled enough to prevent injury. We built a model based on an agar phantom in order to experimentally study the thermal behavior of this balloon by measuring the temperature not only on the balloon, but also at a hypothetical point between the esophageal lumen and myocardium (2 mm distant). Controlled temperature (55 {sup 0}C) ablations were conducted for 120 s. The results showed that (1) the cooling balloon provides a reduction in the final temperature reached, both on the balloon surface and at a distance of 2 mm; (2) coolant temperature has a significant effect on the temperature ...
From autumn this year, the FRJ-2 of the Research Center Juelich will be supplying molybdenum targets to the Institut National des Radioelements in Fleurus, Belgium - which deals in medical radio-isotopes worldwide - thus helping to meet the need for technetium-99, which is used in the medical profession for diagnostic purposes because of its favourable radiological characteristics. Technetium-99 is formed as a result of the radioactive decay of molybdenum-99. For many years now, molybdenum has been produced by the irradiation of uranium in research reactors, so that the initiation of molybdenum production in the FRJ-2 is not especially new. What is unusual, however, are the particular peripheral conditions which result from the combination of the irradiation requirements, a predetermined target design and the technical characteristics of the reactor and which necessitated special solutions. This applies especially to the handling of the targets after irradiation, which is much more ...
The further optimisation and improvement of the efficiency of internal combustion engines require the realisation of new technologies leading to a distinctively faster warm-up behaviour of the coolant and lubricants as well as of the engine components after a cold start. In order to achieve reduced fuel consumption and exhaust gas emissions with the help of heat management, the design criteria of innovative cooling systems need to be reflected and adapted to future requirements. The use of intelligent components within the cooling system, such as the 'Stand Alone Rotary Valve' as a thermostat's substitute or the use of coolant pumps with a rotary valve integrated into the pump's inlet chamber, offer new ways to realise in a decisively quicker and more flexible way the appropriate heating up and cooling down procedures at varying driving conditions. A description of both of the intelligent components for the cooling system is given in this paper. The ...
The experimental effect investigation programme on Zircaloy-4/air oxidation was pursued and expanded to isothermal specimen exposure and the comparison of the oxidation between the atmospheres Ar/O{sub 2} and air. In close connection with the EC project OPSA, which is meanwhile terminated, the investigation concerned specimen exposure in a thermobalance to flowing atmospheres, namely dry Ar/O{sub 2} of composition 80/20 or synthetic air, respectively. As test parameters the linear heat-up rate was varied in the range 5 to 40 K/min and the ramp or holding temperature between 800 and 1500 C. Mass increase and reaction rate were continuously recorded or evaluated in temperature/time dependence. The oxide scale growth was found to be accompanied by colour changes, crack formation and spalling of layers, as well as by dimensional substrate growth, which are the reasons for the observed kinetic results. The microstructural investigation confirms nitrogen to be essentially responsible for the ...
By using defined compositions based on industrial wastes of the hard-coal mining and a further waste material (red mud), which is obtained during the extraction process of alumina (BAYER-Process), it is possible to produce expanded-clay granulate requiring suitable preparation, shaping and firing at temperatures of about 1150 C. Some of the investigated parameters and aspects of this manufacturing process will be presented in this paper. (orig.) [German] Aus definierten Mischungen industrieller Reststoffe des Steinkohlenbergbaus (Bergematerial) mit einem weiteren Abfallstoff (Rotschlamm), der bei der Aluminiumoxidgewinnung nach dem BAYER-Verfahren anfaellt, laesst sich nach geeigneter Aufbereitung und Formgebung durch Brennen bei ca. 1150 C Blaehton-Grunulat herstellen. Auf einen Teil der untersuchten Parameter und ermittelten Zusammenhaenge soll im folgenden naeher eingegangen werden. (orig.)
The authors investigated the development of tribochemical reaction layers and surface-level structural changes in a fuel-lubricated roller bearing steel 100Cr6 in the limiting friction range, using two different variants of surface treatment and heat treatment. Tribological experiments were carried out in a laboratory test stand with reversing sliding wear under varying loads and with a varying number of friction cycles. [German] Ziel der vorliegenden Arbeit war es, die Entstehung von tribochemischen Reaktionsschichten und oberflaechennahen Gefuegeaenderungen am Waelzlagerstahl 100Cr6 bei Kraftstoffschmierung im Grenzreibungsbereich fuer je zwei Oberflaechenbearbeitungen und Waermebehandlungen zu untersuchen. Dazu wurden tribologische Kurzversuche in einem Laborpruefstand mit reversierender Gleitbeanspruchung unter Variation der Last und der Anzahl der Reibzyklen durchgefuehrt. (orig.)
A system for partial mechanisation of the support work with roadway driving machines consisting of a crawler undercarriage carrying a selective cutter with a cutting jib on a rotary tower is claimed. The system comprises a support manipulator movable in longitudinal direction over the rotary tower and cutting jib and a preassembly table with a number of brackets to take up and preassemble a support structure consisting of profile segments, preferably an arc-shaped support with a cap made up for several parts. The system is characterized in that the preassembly table is mounted on one side of the selective cutter and has one straight vertical guide bar each for at least two cap brackets which can be continuously adjusted in height, and in that the manipulator mounted on the selective cutter has a horizontally suivelling head which may grip under the cap of the preassembled structure on the preassembly table.
In this study, the bend properties of the single-crystalline molybdenum brazed by using Mo-40%Ru alloys containing boron of 1-6 mass%Ru alloy for the improvement of the joint strength was determined. (orig.) [Deutsch] Durchgefuehrt wurde die Herstellung von Verbindungen aus einkristallinem Molybdaen. Hierbei kamen Mo-40%Ru-Legierungen mit 1 bis 6 Gew.-% Bor als Lotmaterialien zum Einsatz. Festigkeit und Duktilitaet der Verbindungen wurden mittels 3-Punkt-Biegepruefung bei Raumtemperatur und unter fluessigem Stickstoff ermittelt. Die Bruchflaechen der Proben wurden mit Hilfe eines Rasterelektronenmikroskopes untersucht. Die Ergebnisse lassen sich wie folgt zusammenfassen: Der optimale Borgehalt bezueglich Festigkeit und Duktilitaet der geloeteten Verbindung liegt bei 2 Gew.-%. Die entsprechende Probe hat bei einem Biegewinkel von 100 bei Raumtemperatur nicht versagt. Auch unter fluessigem Stickstoff zeigte diese Probe eine Festigkeit in der Groessenordnung des ...
The stirling cryocooler ILK 15 is a machine with simple drive concept. This machine works with a conventional built-in electric motor and crank drive and needs a power input of about 500 W. The refrigerating capacity is 15 W at 80 K with a cooldown time of 12 minutes. The cooler is somehow a replacement for the Gifford-McMahon cycle coolers, which are bigger and heavier. The Stirling cryocooler was designed to cool HTSC-components. (orig.) [Deutsch] Der Stirlingkuehler ILK 15 ist eine Kaeltemaschine mit einfachem Antriebskonzept. Die Maschine arbeitet mit einem konventionellen Elektroeinbaumotor und Kurbeltrieb. Sie benoetigt eine Antriebsleistung von 500 W und hat eine Kaelteleistung von 15 W bis 80 K und eine Einkuehlzeit von 12 Minuten. Die Maschine kann als Alternative zur wesentlich groesseren und schweren Gifford-McMahon-Maschine gesehen und bei der Kuehlung von HTSL-Komponenten eingesetzt werden. (orig.)
Sprengel deformity is a congential malformation with usually unilateral elevation and medial rotation of the scapula. An omovertebral bone is generally present. Associated skeletal malformations are frequently present. Though functional impairment is mild, the cosmetic and psycho-social impairment can be considerable. The prognosis of early surgical therapy is good. The presented case also justifies surgical correction in the older child. (orig.) [German] Die Sprengel-Deformitaet ist eine angeborene Fehlbildung mit meist einseitiger Elevation und Medialrotation der Skapula. Meist ist ein Os omovertebrale vorhanden. Assoziierte skelettale Fehlbildungen sind haeufig. Obgleich funktionell wenig einschraenkend, ist die kosmetische und psycho-soziale Beeintraechtigung oft erheblich. Die Prognose der fruehen operativen Therapie ist gut. Der vorliegende Fall ermutigt zur operativen Therapie auch im hoeheren Kindesalter. (orig.)
By retrofitting the existing steam turbine dual purpose power plant with a gas turbine plant and a secondary waste heat boiler the Technische Werke Ludwigshafen AG have considerably improved the energy generation in energetic, economic and ecological terms. The extension of the existing system to a combined cycle process has lead to this positive effect. The erection of a boiler plant during the first two construction phases has fully met the optimistic expectations. (orig.) [Deutsch] Mit der Nachruestung eines vorhandenen Dampfturbinen-HKW um eine Gasturbinenanlage mit nachgeschaltetem Abhitzekessel haben die Technischen Werke Ludwigshafen AG ihre Energieerzeugung entscheidend in energetischer, oekonomischer und oekologischer Sicht optimiert. Insbesondere die Erweiterung des vorhandenen Systems zu einem GuD-Prozess fuehrt zu dieser positiven Bilanz. Die Errichtung der Kesselanlage in den ersten beiden Bauabschnitten hat die optimistischen Erwartungen voll ...
Zusammenfassung Seit Dezember 2009 ist in Deutschland neben einem 10-valenten (PCV10) auch ein 13-valenter Pneumokokkenkonjugatimpfstoff (PCV13) verf?gbar. Ein Wechsel von PCV7 zu PCV13 ist zu jedem Zeitpunkt einer begonnenen Impfserie problemlos m?glich, von PCV7 zu PCV10 nur bei der Boosterimpfung. F?r alle Kinder mit abgeschlossener vollst?ndiger PCV7- oder -10-Impfserie stellt sich die Frage, ob eine zus?tzliche Impfung mit PCV13 sinnvoll ist. Kinder mit erh?htem Risiko f?r Pneumokokkenerkrankungen gem?? STIKO (St?ndige Impfkommission am Robert?Koch-Institut), die mit PCV7, jedoch nicht mit PPV23 geimpft sind, sollten grunds?tzlich mit PCV13 geimpft werden. Zu diesen Risikokindern sind evtl. auch gesunde, aber bereits im fr?hen Alter in Gemeinschaftseinrichtungen betreute Kinder zu rec...
With a pilot electrostatic precipitator having wider plate spacings than usual tests were performed under industrial conditions. In the two-section two-duct pilot precipitator with a precipitation area of 60 m/sup 2/ the plate spacing was increased up to 1,000 mm. As gas velocities values between 0.5 and 2.0 m/s were selected. The precipitator was tested with the flue gases of a coal-fired power station and in the room dedustion of an iron ore sintering plant. Starting with a plate spacing of 250 mm increasing the spacing results initially in a small increase of the precipitation rate. After reaching a maximum the rate decreases and finally with passing a critical spacing it goes below the initial value. Dedusting flue gases the spacing with the maximum and the critical spacing depend on the gas velocity. Cost analyses demonstrate that increasing the up to now used plate spacings may led to considerable savings. Depending on the kind of application plate spacings of about 600 mm seem ...
Optische Uhren nutzen die Anregung optischer Ubergange in neutralen Atomen oder Ionen. Deren Ubergangsfrequenz liegt bei etwa 1015 Hz, also funf Groenordnungen oberhalb der Gigahertz-Schwingungen heutiger Atomuhren. Das erlaubt eine bis zu tausendmal prazisere Zeitmessung. Fur die Genauigkeit ist es entscheidend, dass der Uhrenubergang eine schmale Linienbreite besitzt und seine Frequenz nicht verschoben wird. Dazu mussen die Atome oder Ionen moglichst ungestort und genau lokalisiert sein. Deshalb basiert ein Uhrentyp auf einem kalten Ion in einer Paul-Falle, ein anderer Uhrentyp arbeitet mit vielen kalten Neutralatomen in optischen Gittern. Der Metrologie sollen optische Uhren zunachst als sekundare Realisierung der Sekunde dienen. Derzeit ermoglichen sie bereits Frequenzmessungen mit 17 ...
Flow Tex and ABB Energiekabel GmbH have developed a technique which allows the recovery of cables without requiring any trenching works. The new technique was successfully used for the first time for a pilot project in 1995. The authors report on two recent recovery projects (1998) in which an optimised technology was used for recovering a total of 1 500 m system length of 110 kV low-pressure oil-filled cables in Stuttgart and Munich on very different conditions. The authors describe the operational experiences with the cable connections and highlight the background stipulating the removal of the cables. (orig.) [Deutsch] Ein Verfahren zur grabungsfreien Bergung von Kabeln, gemeinsam entwickelt von FlowTex und ABB Energiekabel, wurde erstmals in einem Pilotprojekt 1995 mit Erfolg eingesetzt. Die Verfasser berichten ueber zwei Bergungsprojekte, bei denen 1998 mit der optimierten Technik in Stuttgart und Muenchen insgesamt 1 500 Systemmeter ...
The harnessing and enhanced use of renewable energy today is a matter of lively debate and much concern. Amazingly, hydro power is either rarely considered in these discussions or viewed in a negative light. But hydro power continues to be the most important source of renewable energy, and its use potential is considerable and should be taken into account when, for instance, agreeing on or implementing carbon dioxide reduction targets. Small hydro power stations are an effective means of harnessing existing energy potentials. (orig.) [Deutsch] Ueber die Nutzung und den Ausbau regenerativer Energien wird heutzutage lebhaft diskutiert und gerungen. Es mag erstaunen, dass in diesen Diskussionen die Wasserkraft kaum Beachtung findet oder in einem schlechten Licht gesehen wird. Dabei ist die Wasserkraft nach wie vor bei weitem die wichtigsten Quelle regenerativer Energie, und sie besitzt ein beachtliches Ausbaupotential, das man wenigstens ins Kalkuel ziehen sollte, ...
The new multi-purpose oxygen cupola furnace is a coke-fired shaft furnace that is operated on pure oxygen. The top gas is recirculated, and the fumes are drawn off at temperatures ranging from 800 to 1 000 C. The furnace offers the possibility of melting down contaminated and zinc-bearing scrap without the occurrence of any environment-polluting gas emissions. The absence of nitrogen ballast permits a high energy efficiency. (orig.) [Deutsch] Der neue Mehrzweck-Sauerstoff-Kupolofen ist ein koksbeheizter Schachtofen, der mit reinem Sauerstoff betrieben wird. Das Gichtgas wird im Kreislauf gefuehrt, und das Abgas wird aus einem Bereich mit Temperaturen von 800 bis 1 000 C abgefuehrt. Der Ofen bietet die Moeglichkeit, verunreinigte und zinkhaltige Schrotte einzuschmelzen, ohne dass umweltbelastende Gasemissionen auftreten. Der fehlende Stickstoffbalast bewirkt einen hohen energetischen Wirkungsgrad. (orig.)
Under the new name of ``geothermal heat pump``, ground-source heat pumps are currently high in demand in Northern America. In sectors characterized by heating and cold air demand, their advantages can be exploited to the full. For Germany, the end-use-energy substitution potential of geothermal heat pumps has been estimated at 1310-1470 PJ annually. Whether this potential can actually be exploited depends essentially on the development of energy prices, but also on the resourcefulness of plant and heat pump manufacturers in upgrading and cheapening geothermal heat pumps. (orig./RHM) [Deutsch] Unter der neuen Bezeichnung `Geothermal Heat Pump` erlebt die erdgekoppelte Waermepumpe z.Zt. in Nordamerika einen Verbreitungsschub. In dem durch Heiz- und Kuehlbedarf charakterisierten Umfeld kann sie Ihre Vorteile voll nutzen. Fuer Deutschland kommt eine Schaetzung zu einem Potential der erdgekoppelten Waermepumpen zur Substition von Endenergie von 1310-1470 PJ/a. Ob dieses ...
Burner nozzles were often redesigned in order to improve flow design and manufacturing quality. Maintenance intervals, however, are not satisfactory for the operators of such plants. There is no definitive answer as to whether upgraded design allows to lengthen these intervals or whether additional measures are required. Gas turbines may break down for a large number of reasons. This article shows that many of the causes of operational failure and damage are preventable. Damage management will be successful if manufacturers, operators and independent institutions work together.(orig.) [German] Es wurden in der Vergangenheit mehrfach Veraenderungen an den Brennerduesen vorgenommen. Dabei wurden Verbesserungen in der stroemungstechnischen Auslegung und der Fertigungsqualitaet erzielt. Die derzeit noch gueltigen Wartungsintervalle sind fuer den Betreiber unbefriedigend. Inwieweit diese Intervalle mit der modifizierten Ausruestung verlaengert werden koennen oder ob weitere Massnahmen ...
A team at the Paul Scherrer Institute (PSI) recently achieved a breakthrough in the development of an environment-friendly and rechargeable battery with novel electrodes. The energy storage density of a rechargeable 12 V/20 Ah zinc/air battery could be increased to 100 watt hours per kilogramme - three times as much as conventional lead accumulators. 20-Ah cells could be charged and discharged 55 times in 1000 hours without any loss of capacity worth mentioning. This is a remarkable cycle stability. (orig.) [German] Einem Team des Paul Scherrer Instituts (PSI) ist kuerzlich bei der Entwicklung einer umweltfreundlichen und wiederaufladbaren Batterie mit neuartigen Elektroden der Durchbruch gelungen. Dabei konnte die Energiespeicherdichte einer wiederaufladbaren 12 V/20 Ah-Zink-Luft-Batterie auf 100 Wattstunden pro Kilogramm gesteigert werden - dreimal soviel wie bei konventionellen Bleiakkumulatoren. 20-Ah-Zellen konnten in 1000 Stunden ohne nennenswerte ...
Pulmonary tumors in children are rare. Nevertheless, there are besides malign primary neoplasms and metastases also some benign tumors that the radiologist should know. The identification of some tumors is difficult, since some of them may mimic pulmonary inflammation. The first diagnostic tool is chest radiography. After that, a CT with contrastmedium should be performed, if possible a multislice-CT (MSCT). Identification of mediastinal structures is best with MRI. (orig.) [German] Tumoren der Lunge sind im Kindesalter selten. Trotzdem finden sich neben den malignen primaeren und sekundaeren Raumforderungen auch im Kindesalter immer wieder benigne Tumoren, die der Radiologe kennen sollte. Eine eindeutige Identifizierung kann schwierig sein, da z. B. entzuendliche Infiltrate vorgetaeuscht werden koennen. Die primaere Untersuchungsmethode ist das konventionelle Thoraxroentgen. Die weitere Diagnostik muss mit der Computertomographie, nach Moeglichkeit mit einem ...
Shell Solar GmbH is working on a variant of the so-called stacked elemental layer process for CIGSSe absorber production. The metal films resp. the selenium are deposited on the Mb electrode at room temperature by DC sputtering (CIG) or evaporation (Se) and then processed into semiconductors by rapid thermal annealing (RTP). Currently, the mean efficiency of the pilot plant is i 12.6 {+-} 0.2 % for non-sealed 30 x 30 cm{sup 2} modules, the key efficiency is 13.0 %. In addition to the 30 x 30 cm{sup 2} pilot line, a small series of 60x90cm2 modules was constructed in December 2004. Here, the mean efficiency was 13.0 percent while the average module power was higher than 60 W. The contribution also describes investigations of ceramically sputtered n-ZnO:Al layers with reduced Al concedntrations of 1 percent and on reactively sputtered n-ZnO.Al layers from the double roller magnetron. (orig.) [German] Bei Shell Solar GmbH wird eine Variante des sogenannten ...
Purpose: To evaluate the success rates of the implantation of stent grafts in the treatment of peripheral aneurysms. Materials and methods: in 13 patients with 15 aneurysms at the common iliac artery (n = 6), external iliac artery (n = 1), hypogastric artery (n = 2), femoral artery (n = 2) or popliteal artery (n = 4), implantation of dacron-covered nitinol stents was performed. The patients were followed up for three to 20 months (mean, 8.8 months) with intravenous digital subtraction angiography, CT or colour-coded Doppler sonography. Results: In all cases, the aneurysm was successfully occluded after stent implantation. In one case with a popliteal aneurysm, kinking of the vessel caused thrombosis of the stent. The stent was successfully reopened. The aneurysm however, had to be surgically treated 9 months later. The primary and secondary patency rates at 6 months were 93% and 100%, respectively. Conclusion: The method described might be an alternative therapy to surgery. There are ...
Purpose: Small suspicious breast lesions that are only visible at MR imaging were preoperatively marked with a hook wire under MR-guidance to allow the removal of the lesion with tissue-sparing surgery. Method: In all patients the suspicious lesions were marked preoperatively under MR guidance with a hook wire using a commercially available stereotactic device. Interventions were performed with MR guidance on a 1.0 T and on a 1.5 T system. Results: In 19 patients 22 lesions were localized. One lesion was missed and removed in a second procedure. The mean duration for localization was 66{+-}20 min (range 38-119 min). In two patients two lesions were localized. The mean deviation of the wire tip to the lesion was 2,0{+-}2,6 mm. In this series, 6 of 22 lesions were malignant. The mean diameter of the lesion was 7.6{+-}2.6 mm (range 3-14 mm). Conclusion: Suspicious breast lesions detectable only in MR imaging can be accurately localized with a hook wire preoperatively under MR control to ...
Purpose: In vitro evaluation of possible deflection and heating of present-day prosthetic heart valves, 12 technical and 5 biological, were investigated using a 1.5 Tesla Siemens Vision system. Deflection was measured at the edge of a 1.5 Tesla superconducting magnet. Each valve was then submerged in a vial of a 1/1 electrolyte solution and temperature was measured before and after imaging with a turbo-spin-echo sequence (TR 5200 ms, TE 138 ms, Flip angle 180 C, acquisition time 10.5 minutes, length of echo train 29). MR imaging was performed with phase encoding parallel and perpendicular to the plane of the valves. Results: None of the investigated prosthetic heart valves was deflected. The maximal observed temperature rise was 0.5 C. During MR investigation of the prostheses, artifacts caused by metallic parts were less evident using a spin-echo sequence than a gradient-echo sequence. Conclusions: Patients with the tested present-day prosthetic heart valves can be safely imaged by ...
In technical combustors, flow and combustion processes inside the combustion chamber determine the design and also the safety of the plant. A modelling technique was developed at TU Dresden which comprises both numerical simulations and experimental data and thus achieves a high degree of transparency in its visualisation of the processes inside the combustion chambers under investigation. With the experience gained, numerical models of commercial simulation software (FLUENT, CFX) can be validated by measured values, and potential applications of the programs can be investigated. The first stage of experimental modelling consisted in isothermal (cold) modelling in consideration of flow-relevant similarity characteristics. In the reactive, non-isothermal models, the fuel/air ratio and temperature conditions inside the original combustion chamber were modelled as well. In order to obtain detailed data on the combustion conditions at the burner, measurements were made on a separate ...
A new emissivity measurement device with inductive sample heating is described. The disc shaped samples can be measured between 800 C and 2000 C in vacuum or in each available gas atmosphere. Two kinds of surface temperature measurement methods are described, one by measuring in a blackbody hole and one by measuring at the surface without additional measures to correct emissivity. Total normal and spectral emissivity at wavelengths between 0,5 {mu}m and 8,3 {mu}m of various high temperature materials like platinum and Pt-Rh-alloys, siliconcarbide and molybdenum disilicide have been measured. From the investigated materials a few have been selected as reference samples for comparative emissivity measurements fullfilling the requirement of stability on air up to 400 C to 1000 C in order to ensure reproducibility of the results at different measurement conditions in air and in vacuum. (orig.) [Deutsch] Der Aufbau einer neuen Messapparatur fuer Emissionsgradmessungen bei Temperaturen ...
It is demonstrated that highly dispersed molybdenum sulfide catalysts are prepared by using Mo(CO){sub 6} adsorbed on the support. The structure of ultradispersed molybdenum sulfide is suggested by EXAFS techniques to be different from that of MoS{sub 2}. The TOF of the thiophene HDS is almost invariant with the dispersion of molybdenum sulfide at a high molybdenum dispersion, whereas the TOF of the hydrogenation greatly increases with increasing dispersion. On the basis of the HDS activity and optimum Co/Mo ratio of Co-Mo/Al{sub 2}O{sub 3} catalysts having a variety of molybdenum dispersion fabricated by using carbonyl complexes, it is demonstrated that highly active HDS catalysts are prepared by highly dispersing molybdenum sulfide phases. Edge decorations of molybdenum sulfides by cobalt are suggested for the synergy generation between cobalt and molybdenum sulfides. (orig.) [Deutsch] Unter Verwendung von auf dem Traeger adsorbierten Mo(CO){sub 6} lassen sich hochdispergierte ...
Already, MR Imaging is superior in diagnostic imaging of joints in many cases; however, there have been recent developments, which are the subjects of this paper. With gradient-echo sequences acquired in 3D technique, it is possible to produce high-resolution images of joints in acceptable scantime, because gradient-echo sequences are less time-consuming than convential SE sequences. With the acquisition of two echoes, phase difference between water and fat protons have to be considered. 3D Imaging is capable of displaying complex pathology in a superior way, which should be useful in preoperative planning. Tissue contrast is altered by fat saturation or magnetization transfer in order to achieve better conspicuity of lesions. Although diagnostic value of some of these options is not yet clear and further clinical studies are needed, they are a promising possibility for improving MR Imaging of the joints. (orig.) [Deutsch] In der Gelenkdiagnostik gibt es einige neuere Entwicklungen in ...
Policy strategies for the promotion of electricity from renewable energy sources differ significantly among the Member States of the European Union with respect to the amount of additional installed capacity as well as concerning the country-specific support costs. The present report aims to assess the effectiveness and the economic efficiency of the support policies in the EU based on both historical experiences and prospective model-based analysis. The main message of the investigation is that the most effective policy instruments tend to be cost-efficient at the same time. In particular, feed-in tariff systems were identified as a successful instrument for supporting renewable energies in terms of effectiveness and efficiency, whereas quota systems still have to prove themselves in practice. (orig.) [German] Bezueglich des Erfolges bei der Foerderung erneuerbarer Energietraeger im Stromsektor bestehen deutliche Unterschiede zwischen den Mitgliedsstaaten der ...
It is necessary to measure strength and creep behavior to guarantee the safe and reliable usage of refractory alloys at extremely high temperatures. In the literature there is very little information available about the properties of Mo-Re alloys at temperatures higher than 1000 C. A special test facility has been designed and built for stress-rupture testing at very high temperatures (up to 3000 C) of refractory metals and alloys in inert atmospheres. - The stress-rupture strength as well as the creep behavior of molybdenum-rhenium alloys with rhenium contents between 41 and 51 wt.% have been determined at temperatures ranging from 1200 to 2000 C, and rupture times of up to 10 hours using this facility. Previous measurements of stress-rupture strength and creep behavior of pure rhenium have been compared with the measurement results of Mo-Re alloys. - The discussion of the values measured is based on metallographic test results and scanning electron microscopy (SEM) images of Mo-Re ...
The typical MRI features of the most common pancreatic diseases, such as pancreatitis and adenocarcinoma of the pancreas, have been established. However, even in these common pancreatic disorders, MRI correlation with the underlying pathology is limited for clinical reasons. We emphasize MR-pathological correlation of inflammatory and neoplastic pancreatic changes, including pancreatitis, adenocarcinoma, acinar cell carcinoma, rare cystic and solid pancreatic neoplasms, and islet cell tumors. By highlighting the correlation of key pathological features with MR findings, a better understanding of the MR appearance of pancreatic pathology can be provided. In addition, MRI may prove a powerful tool in detection and characterization of pancreatic tumors. (orig.) [Deutsch] Das MR-tomographische Erscheinungsbild von Pankreatitiden und Adenokarzinomen des Pankreas, als den haeufigsten Pankreaserkrankungen, ist zwar ausreichend bekannt; allerdings ist selbst bei diesen Pankreaserkrankungen die ...
The evaluation of possible manufacture-based defects in turbine shafts and housings for component serviceability relevance is of particular interest not only in post-manufacturing NDT but also in evaluation of NDT results obtained by in-service inspections of components with long service lives. The results discussed in the paper are summarized as follows: Most of the examined natural defects in the forgings and castings behave like cracks under the simulated operating conditions and hence may well be evaluated by fracture mechanical methods for their serviceability relevance determined by crack propagation under fatigue, creep and creep-fatigue stress. The empirical correlation of true defect size and US testing results (echo signal, echodynamics, attenuation) permits improved determination of true defect sizes in the turbine components. Care has to be taken to select the proper testing and evaluation methods in compliance with defect types. (orig./MM) [Deutsch] Die ...
Alloyed steels containing retained austenite after martensitic hardening are widely applied in technical practice. Although many practical investigations have been made into the mechanical behaviour of composite microstructures with retained austenite, there is still a lack of knowledge concerning their fatigue and crack propagation behaviour. For this reason, the author investigated the effects of retained austenite concentration and stability on the transformation and deformation behaviour of hardened states of the steels X210Cr12 and 100Cr6. For this purpose, monotone tensile tests, cyclic tensile pressure tests, and supplementary crack propagation experiments were carried out. The concentrations of retained austenite were varied between 10 and 100% by volume by means of different heat treatments. [Deutsch] Legierte Staehle, die nach martensitischer Haertung noch Restaustenit enthalten, finden in der technischen Praxis verbreitete Anwendung. Zum mechanischen Verhalten von ...
The fibre reinforcement of ceramic materials is used above all to improve the toughness and tolerance of damage, compared to unreinforced monolithic ceramics. This improvement is made possibly by the bridging effect of the cracks by the fibres in crack propagation in the matrix. In this work, the crack bridging effect of the fibres is included in a bridge stress equation, in which a clear relationship between bridge stress and crack opening is determined. The most important step for deriving the bridge stress law was determining the probability of failure of a fibre for a given axial stress curve. One relied on the micromechanical analysis of Hutchinson and Jensen here, by which the boundary conditions in multi-fibre materials can be included and realistic assumptions can be made for the load transfer mechanisms in the fibre/matrix boundary surface. (orig./MM) [Deutsch] Die Faserverstaerkung keramischer Werkstoffe dient vor allem zur Verbesserung der Zaehigkeit und Schadenstoleranz ...
Isothermal reaction experiments were performed in the temperature range of 1000 - 1300 C in order to determine the chemical interactions between Zircaloy-4 fuel rod cladding and Inconel-718 spacer grids of Pressurized Water Reactors (PWR) under severe accident conditions. It was not possible to apply even higher temperatures since fast and complete liquefaction of the components occurred as a result of eutectic interactions during heatup. The liquid reaction products formed enhance and accelerate the degradation of the material couples and the fuel elements, respectively. Only small amounts of Inconel are necessary to liquefy large amounts of Zircaloy. Thin oxide layers on the Zircaloy surface delay the beginning of the chemical interactions with Inconel but cannot prevent them. In this work the reaction kinetics have been determined for the system: as-received and pre-oxidized Zircaloy-4/Inconel 718. The interactions can be described by parabolic rate laws; the Arrhenius equations for ...
Phase contrast X-ray imaging has been studied intensively using X-rays from synchrotron radiation and micro-focus X-ray tubes. However, these studies have revealed the difficulty of this technique's application to practical medical imaging. We have created a phase contrast imaging technique using a molybdenum X-ray tube with a small focal spot size for mammography. We identified the radiographic conditions in phase contrast magnification mammography with a screen-film system, where edge effect due to phase contrast overcomes geometrical unsharpness caused by the 0.1 mm-focal spot of a molybdenum X-ray tube. The edge enhancement due to phase imaging was observed in an image of a plastic tube, and then geometrical configuration of the X-ray tube, the object and the screen-film system was determined for phase imaging of mammography. In order to investigate a potential for medical application of this method, we conducted evaluation of the images of the American Collage of Radiology (ACR) ...
As part of a U.S. multi-regional pilot study conducted by the six Centers for Radiological Physics, 12-mm-diameter by 0.4-mm-thick CaSO/sub 4/:Dy Teflon-embedded discs were evaluated and used to measure patient entrance exposure on 60 average patients at 12 clinical centers. The discs were found to have adequate sensitivity, reproducibility and linearity up to 69.7 microC kg-1 (270 mR). The minimum measurable exposure was estimated as 0.4 microC kg-1 (1.5 mR). All responses were corrected for energy dependence, which varied +/- 20% from 1.7 to 6.5 mm Al half-value layer. Patient entrance exposure values ranged from 1.3 to 28 microC kg-1 (5 to 110 mR), with a median value of 5.2 microC kg-1 (20 mR). This value agreed with exposure measurements made on the chest radiography equipment using an ionization chamber and a phantom which simulated an average patient, and with published Nationwide Evaluation of X-Ray Trends (NEXT) data for the same period.
In the convolution/superposition method of photon beam dose calculations, inhomogeneities are usually handled by using some form of scaling involving the relative electron densities of the inhomogeneities. In this paper the accuracy of density scaling as applied to primary electrons generated in photon interactions is examined. Monte Carlo calculations are compared with density scaling calculations for air and cork slab inhomogeneities. For individual primary photon kernels as well as for photon interactions restricted to a thin layer, the results can differ significantly, by up to 50%, between the two calculations. However, for realistic photon beams where interactions occur throughout the whole irradiated volume, the discrepancies are much less severe. The discrepancies for the kernel calculation are attributed to the scattering characteristics of the electrons and the consequent oversimplified modeling used in the density scaling method. A technique called the kernel integration ...
Pain is necessary for survival but chronic pain is disabling and causes significant health and economic problems. This study provides an understanding of the future for spinal cord stimulation. Stimulation by means of chronically implanted electrodes, was carried out in 200 patients with pain of varied benign organic etiology. In 177 of them, pain was confined to the failed back syndrome. Most patients were referred by a Pain Management Service. 226 epidural implants were used: 80 unipolar, 59 Resume, 12 bipolar, and 75 quadripolar. Patients were followed for periods of 6 months to 12 years, with a mean follow-up of 44 months. 84 patients (42%) were able to control their pain by stimulation alone, 22 patients (11%) needed occasional analgesic supplements along with their stimulation program. Pain secondary to failed back syndrome, multiple sclerosis, peripheral vascular disease, sympathetic dystrophy and diabetic neuropathy responded favorably. Pain due to cauda equina injury, ...
Quantitative gated SPECT (QGS) was evaluated in 7 normal volunteers and 31 patients with cardiac diseases. Adequate cut off value of a prefilter was 0.45. In phantom, the left ventricular volume value was 93.9% of determined value by 180-degree projection in L type and 98.8% by 360-degree projection in opposed type. In normal volunteers, LVEF measured by QGS program related to value by first pass method. As for functional map, regional EF and wall motion decreased at the septum side, and wall thickening at base side of heart. Good correlation was recognized (p<0.0001) between blood flow image and functional map (regional EF and wall thickening). In 20 cases of acute myocardial infarction, lesion was detected conspicuously in regional EF and wall motion. The accuracy of coronary arterial stenosis improved in functional map (regional EF 92%, wall motion 92% and wall thickening 88%). In particular, the accuracy of 3 rami lesion was 100% in functional map and higher ...
Both x-ray and optical cone-beam CT (CBCT) scanners are limited by scattered photons that contaminate the primary images. Transparent radiochromic gels and plastics are anticipated to produce less scattering than polymerization gels and hence result in reconstructed dose distributions with greater contrast and dynamic range. Four methods of scatter measurement were investigated to quantify scatter fractions using an in-house optical CBCT scanner. The methods consisted of generating either 'coin' shadows or primary beamlets in transmission images. The four methods generated similar results of 10% scatter fractions in gel transmission images for this particular scanner configuration with both leuco crystal violet and carbon black micelle gels. The scatter contributions were distributed as 5% from micelle gel, 2% from Teflon wall, 2% from refractive index matching liquid and 1% other sources. Applying a uniform background subtraction of 2% of open field intensity ...
Pharmacokinetics is studied, radiation doses to patients when using domestic thallium-201 chloride in diagnosis of the heart ischemic disease is estimated; contribution into the total dose of thallium-201 (1.5 %), thallium-201 (0.2 %) and lead-201 + lead-203 (0.05 %) radionuclide impurities is also determined. Internal doses were estimated for a heterogeneous phantom of a standard man; the calculations were carried out using a computer. Scanning of patients which were treated with radiopharmaceuticals to be diagnosed was carried out using a whole body counter and gamma-chamber. Large intestine, kidneys and thyroid are the critical organs when using thallium-201 chloride. The highest contribution into the dose to organs and the whole body from thallium-200 and thallium-202 impurities being contained in thallium-201, doesn't exceed 8.6 %. The contribution into the dose from lead-201 and lead-203 may be ignored. Doses from thallium-199 preparation per activity unit ...
Measurements were carried out for calibration and performance testing of a set of 10 electronic personal dosimeters (EPDs) at the Secondary Standard Dosimetry Laboratory of Sudan. Calibrations were carried out at three X-ray beam qualities described in ISO standard 4037 in addition to 137Cs and 60Co gamma ray beams. The experimental was performed with EPDs mounted on ICRU Slab phantom. X-ray and ?-ray beams were characterized in terms of air kerma free-in-air which were converted to the known delivered personal dose equivalent, Hp(10) using appropriate the air kerma to personal dose equivalent conversion coefficients. Dosimeters tested showed excellent energy and angular response and relative error of indication within the recommended limit for photon energies from 65 keV to 1.25 MeV. The study showed encouraging results for using electronic dosimeters in personal dosimetry.
Dose reconstruction is a process that re-creates the treatment-time dose deposited in a patient provided there is knowledge of the delivered energy fluence and the patient's anatomy at the time of treatment. A method for reconstructing dose is presented. The process starts with delivery verification, in which the incident energy fluence from a treatment is computed using the exit detector signal and a transfer matrix to convert the detector signal to energy fluence. With the verified energy fluence and a CT image of the patient in the treatment position, the treatment-time dose distribution is computed using any model-based algorithm such as convolution/superposition or Monte Carlo. The accuracy of dose reconstruction and the ability of the process to reveal delivery errors are presented. Regarding accuracy, a reconstructed dose distribution was compared with a measured film distribution for a simulated breast treatment carried out on a thorax phantom. It was found ...
A thermoluminescence (TL) sheet and its spatial readout system for in vivo measurement of spatial dose distribution around sources has been newly developed for intracavitary high dose-rate radiation therapy. The TL sheet (40 cm x 50 cm x 200 {mu}m), which is composed of teflon mixed with BaSO{sub 4} (Eu doped) powder, has a linear response with a very wide dynamic range from at least 0.002 cGy to 5000 cGy for {sup 60}Co sources. Phantom test of the TL sheet readout system demonstrated that absorbed dose with TL sheet and that with ionization chamber as standard dosimeter agreed well. For clinical application, TL sheet was attached on an applicator of intracavitary radiation therapy for rectal cancer. After irradiation with high dose-rate {sup 60}Co sources, the in vivo dose distribution on the surface of the rectum was determined. The TL sheet was suggested to provide a convenient means of measuring the dose distribution around {sup 60}Co sources in intracavitary ...
The dose distribution in a Rando phantom has been measured for typical EMI 5005 CT scans of the head, chest, abdomen and pelvis. These dose distributions have been used to generate quantitative estimates of the somatic and genetic radiation risks associated with these CT examinations and also to measure the total energy imparted during each scan. A comparison has been made between the radiation risk estimates and the energy imparted measurements. The energy imparted measurements are not a good indicator of the somatic and/or genetic risks when one type of CT scan is compared with another. However, for a given type of scan, the energy imparted may be a reasonable indicator of the relative somatic risks associated with different CT examinations. Considerable care should be taken when interpreting and using any measured value of energy imparted in a radiological examination since published values of the risk per unit energy imparted can significantly underestimate the ...
Experiments were conducted to confirm the isotropic spatial resolution of multislice CT with a 0.5 mm slice thickness. Isotropic spatial resolution means that the spatial resolution in the transaxial plane (X-Y plane) and that in the longitudinal direction (Z direction) are equivalent. To obtain point spread function (PSF) values in the X-Y-Z directions, three-dimensional voxel data were obtained by helical scanning of a bead phantom. The modulation transfer function (MTF) values were then obtained by three-dimensional Fourier transform of the PSF. Evaluation of the spatial resolution in the X-Y-Z directions by the MTF values showed that the spatial resolution in the Z direction does not depend on the reconstruction kernel used. It was also found that the spatial resolution in the Z direction, as compared with that in the X-Y plane, is superior with the standard kernel for the abdomen and is inferior with the high-definition kernel for the ears/bones. By performing ...
Molecular imaging represents a modern research area that allows the in vivo study of molecular biological process kinetics using appropriate probes and visualization methods. This methodology may be defined- apart from the contrast media injection - as non-abrasive. In order to reach an in vivo molecular process imaging as accurate as possible the effects of the used probes on the biological should not be too large. The contrast media as important part of the molecular imaging can significantly contribute to the understanding of molecular processes and to the development of tailored diagnostics and therapy. Since more than 15 years PTB is developing optic imaging systems that may be used for fluorescence based visualization of tissue phantoms, small animal models and the localization of tumors and their predecessors, and for the early recognition of inflammatory processes in clinical trials. Cellular changes occur during many diseases, thus the molecular imaging ...
IMRT optimization requires a fast yet relatively accurate algorithm to calculate the iteration dose with small memory demand. In this paper, we present a dose calculation algorithm that approaches these goals. By decomposing the infinitesimal pencil beam (IPB) kernel into the central axis (CAX) component and lateral spread function (LSF) and taking the beam's eye view (BEV), we established a non-voxel and non-beamlet-based dose calculation formula. Both LSF and CAX are determined by a commissioning procedure using the collapsed-cone convolution/superposition (CCCS) method as the standard dose engine. The proposed dose calculation involves a 2D convolution of a fluence map with LSF followed by ray tracing based on the CAX lookup table with radiological distance and divergence correction, resulting in complexity of O(N"3) both spatially and temporally. This simple algorithm is orders of magnitude faster than the CCCS method. Without pre-calculation of beamlets, its implementation is also ...
The dosimetric characteristics for a new brachytherapy seed source (I-Plant"T"M model 3600) were measured using LiF thermoluminescent dosimeters and appropriate phantom materials in conformance with the methodology and guidance provided by the AAPM Task Group 43. The I-Plant"T"M model 3600 is the successor to the I-Plant"T"M model 3500. The major difference between these sources is that the model 3600 contains a leaded-glass core to provide radio-opacity (while the model 3500 contains a silver core), which does not produce spectral contamination upon neutron activation. The dose rate constant #LAMBDA# for the model 3600 was determined to be 1.00 Gy h"-"1 U"-"1 (with a 6% overall relative standard deviation), compared to 1.01 cGy h"-"1 U"-"1 reported for the model 3500 in previous studies. The remaining dosimetric characteristics also are similar for both sources.
Perforated thermoplastic masks are used to provide patients immobilization. This procedure inserts a material in the path of the radiation beam, that attenuates and modifies the beam fluence and flatness. The present study evaluates the increase in skin dose as a result of using thermoplastic masks. Relative doses were measured on the surface of a solid water phantom, in the presence and absence of masks. These masks were stretched according to deformation patterns observed in clinical routine. The measurements were obtained with a plane-parallel chamber (Markus type 23343) and radiochromic film (EBT Gafchromic) for 6MV X-rays from a linear accelerator, and for a radiation beam from a cobalt therapy unit. The results showed that thermoplastic masks, whose thickness varied between 2 and 3 mm, increased the dose on the surface by a factor of 3. Due to the variations in the skin dose distribution, clinical procedures were suggested to minimize radiobiological damages ...
Perforated thermoplastic masks are used to provide patients immobilization. This procedure inserts a material in the path of the radiation beam, that attenuates and modifies the beam fluence and flatness. The present study evaluates the increase in skin dose as a result of using thermoplastic masks. Relative doses were measured on the surface of a solid water phantom, in the presence and absence of masks. These masks were stretched according to deformation patterns observed in clinical routine. The measurements were obtained with a plane-parallel chamber (Markus type 23343) and radiochromic film (EBT Gafchromic) for 6MV X-rays from a linear accelerator, and for a radiation beam from a cobalt therapy unit. The results showed that thermoplastic masks, whose thickness varied between 2 and 3 mm, increased the dose on the surface by a factor of 3. Due to the variations in the skin dose distribution, clinical procedures were suggested to minimize radiobiological damages ...
In electron beam therapy, tissue overdose due to electrons backscattered from lead has been profusely studied. To quantify this dose enhancement effect, an electron backscatter factor (EBF) wasdefined as the ratio of dose at the tissue-inhomogeneity interface with and without the scatterer present. The dependence of the EBF on energy at the scatterer surface is not well known for energies lower than 3 MeV which is the most frequent clinical situation. In this work, we have done Monte Carlo calculations with the GEANT code to study EBF in lead at this energy range. The applicability of this code and the developed procedure for dose estimation has been experimentally verified. The dependence of the EBF on the beam energy incident on the scatterer has been studied for different nominal beam energies incident at the phantom's surface. The results show a trend of increase of EBF with the beam energy incident on the scatterer between 0.5 and 1.5 MeV, keeping ...
Diagnostic capability of Fuji Computed Radiography (FCR) of the chest was compared to the conventional radiography (CoR) using regular film-screen system. FCR utilizers imaging plates of scanning laser stimulated luminescence. Visibility of 14 structures of the chest radiography was evaluated by 3 radiologists in 100 pairs of FCR and CoR which were taken at the same time with the same exposure factors. FCR was superior to CoR especially in observation of the mediastinum and areas behind the heart and diaphragm. The minor fissure was better seen on CoR. Superiority of FCR to CoR was thought to be mainly due to the processed image of FCR, and the so-called normal image of FCR had little diagnostic advantage. Simulated abnormal densities: nodular, alveolar, and interstitial densities with a chest phantom, were made, and detectability of alteration of these densities on FCR and CoR was evaluated by 19 radiologists, using ROC curve analysis. FCR and CoR revealed the ...
Diagnostic capability of Fuji Computed Radiography (FCR) of the chest was compared to the conventional radiography (CoR) using regular film-screen system. FCR utilizers imaging plates of scanning laser stimulated luminescence. Visibility of 14 structures of the chest radiography was evaluated by 3 radiologists in 100 pairs of FCR and CoR which were taken at the same time with the same exposure factors. FCR was superior to CoR especially in observation of the mediastinum and areas behind the heart and diaphragm. The minor fissure was better seen on CoR. Superiority of FCR to CoR was thought to be mainly due to the processed image of FCR, and the so-called normal image of FCR had little diagnostic advantage. Simulated abnormal densities: nodular, alveolar, and interstitial densities with a chest phantom, were made, and detectability of alteration of these densities on FCR and CoR was evaluated by 19 radiologists, using ROC curve analysis. FCR and CoR revealed the ...
Based on a recently introduced phase X-ray imaging approach, a dual-detector prototype was developed for in-line X-ray phase imaging and phase retrieval utilizing a micro-focus X-ray source and two computed radiography (CR) cassette detectors. The system was built on a horizontal optical rail to facilitate manual adjustment of the positions of the X-ray source, the sample and the detectors. The novel design of the detector-1 is essential, it detects a portion of radiation to form an attenuation image; allows the rest of radiation to reach the detector-2 to form a phase contrast image, and the two images are used to retrieve a phase map. The two detectors are balanced for optimal phase-retrieval with reasonable radiation dose to the object to be imaged. The system was examined in terms of the linearity, the fractions of the X-ray photons detected by the two detectors, respectively and the imaging quality of phantoms. Preliminary results showed that the system is ...
For the purpose of risk estimates from radiation carcinogenesis including leukemogenesis and radiation genetic effects, the biological significant dose is not the tissue kerma in air but the absorbed dose in organ or tissue with respect to carcinogenic and leukemogenic effects or genetic effects. In order to estimate organ or tissue dose from the tissue kerma in air, a ratio of the organ or tissue dose to the tissue kerma in air for survivors in Hiroshima and Nagasaki was calculated with the aid of the Snyder's mathematical phantoms constructed so as to simulate the body shape of survivors aged 5, 10 years old and adult at the time of atomic bomb detonations. The ratios were corrected for the angular distribution of atomic bomb radiations, assuming an anisotropic angular distribution for the survivors exposed to the atomic bombs in open air and the isotropic distribution for the survivors incide a Japanese house or other structures. The resultant ratios are ...
In an effort to evaluate the feasibility of introducing computed radiography (FCR) into mass screening for lung cancer, the ability of FCR to detect nodules one cm in diameter was examined using a humanoid chest phantom. Based on the receiver operating characteristic (ROC) analysis, the detectability of FCR was compared with that of conventional radiography and photofluorography. The values of area under ROC curves were higher for FCR (0.963 for image similar to that with conventional film-intensifying screen system, image A; and 0.952 for processed image, image B) than the other two methods (0.774 for radiography and 0.789 for photofluorography). Degradation of image quality in FCR could be avoided by a wide latitude even if proper exposure techniques might not be employed. Images A and B in FCR yielded excellent delineation for nodules in the lung field and in the retrocardiac and subdiaphragmatic regions, respectively. This may have implications for the value of ...
Radiotherapy with high-energy carbon ion beams can be more advantageous compared to photons because of better physical dose distribution and higher biological efficiency in tumour cell sterilization. Despite enhanced normal tissue sparing, damage incurred by normal cells at the beam entrance is unavoidable and may affect the progeny of surviving cells in the form of inheritable cytogenetic alterations. Furthermore, the quality of the beam along the Bragg curve is modified by nuclear fragmentation of projectile and target nuclei in the body. We present an experimental approach based on the use of a polymethylmethacrylate (PMMA) phantom that allows the simultaneous exposure to a particle beam of several biological samples positioned at various depths along the beam path. The device was used to measure the biological effectiveness of a 60 MeV/amu carbon-ion beam at inducing chromosomal aberrations in G{sub 0}-human peripheral blood lymphocytes. Chromosome spreads were ...
The idea to couple the Treatment Planning System (TPS) to the information on the real boron distribution in the patient is the main added value of the new methodology set-up at DIMNP of University of Pisa, in collaboration with the JRC of Petten (NL). The methodology has been implemented in the new TPS, called BDTPS (Boron Distribution Treatment Planning System), which takes into account the actual boron distribution in the patient brain, while the standard TPS assumes a uniform boron distribution, absolutely far from the reality. Nowadays, Positron Emission Tomography (PET) is able to provide this in vivo information. The new TPS, based on the Monte Carlo technique, has been validated comparing the main BNCT parameters (thermal flux, boron dose, etc.) as measured during the irradiation of a special heterogeneous boron phantom (HEBOM), ad hoc designed, as calculated by the BDTPS and by the standard TPS SERA. An evident SERA overestimation of the thermal neutron ...
Modern digital radiographic 'flat panel' detectors can exhibit a progressive form of image degradation arising from non-functioning pixels. The effect of these 'dead pixels' on the quantitative image quality measures of modulation transfer function (MTF), noise power spectrum (NPS) and detective quantum efficiency (DQE) is investigated by a simulated degradation of images obtained from an Hologic EPEX system. The effects on the semi-quantitive measures obtained from contrast threshold test objects and resolution gratings are also investigated. Results suggest that the contrast-detail tests often employed in quality assurance measures are not sufficient to reveal the presence of dead pixels until well beyond the recommended replacement point for the flat panel detector. However, measurements of spatial resolution using a line pairs phantom were found to be more sensitive to pixel loss. Measurement of the MTF, NPS and DQE can ...
Modern digital radiographic 'flat panel' detectors can exhibit a progressive form of image degradation arising from non-functioning pixels. The effect of these 'dead pixels' on the quantitative image quality measures of modulation transfer function (MTF), noise power spectrum (NPS) and detective quantum efficiency (DQE) is investigated by a simulated degradation of images obtained from an Hologic EPEX system. The effects on the semi-quantitive measures obtained from contrast threshold test objects and resolution gratings are also investigated. Results suggest that the contrast-detail tests often employed in quality assurance measures are not sufficient to reveal the presence of dead pixels until well beyond the recommended replacement point for the flat panel detector. However, measurements of spatial resolution using a line pairs phantom were found to be more sensitive to pixel loss. Measurement of the MTF, NPS and DQE can reveal small changes in image quality ...
Accurate dose calculation in radiation treatment planning is most important for successful treatment. Since human body is composed of various materials and not an ideal shape, it is not easy to calculate the accurate effective dose in the patients. Many methods have been proposed to solve inhomogeneity and surface contour problems. Monte Carlo simulations are regarded as the most accurate method, but it is not appropriate for routine planning because it takes so much time. Pencil beam kernel based convolution/superposition methods were also proposed to correct those effects. Nowadays, many commercial treatment planning systems have adopted this algorithm as a dose calculation engine. The purpose of this study is to verify the accuracy of the dose calculated from pencil beam kernel based treatment planning system comparing to Monte Carlo simulations and measurements especially in inhomogeneous region. Home-made inhomogeneous phantom, Helax-TMS ver. 6.0 and Monte ...
The proton beam has an advantage of the sharp dose falloff in dose distribution called Bragg peak while conventional radiation therapy modalities such as photons exhibit considerable amount of exit dose. To take advantage of this property it is important to know the exact location of the distal dose falloff. An error can cause overdose to the normal tissue or underdose to the tumor volume. The only way of finding out the dose distribution in-situ in particle therapy is to measure the gammas produced by nuclear reactions with tissue materials. Two kinds of gammas can be used: one is prompt gamma and the other is coincident gamma from the positron-emission isotopes. We chose to detect prompt gammas, and developed a prompt gamma scanning system (PGS). The proton beams of the proton therapy facility at National Cancer Center were used. The gamma distribution was compared to the dose distribution measured by an ionization chamber at three different energies of 100, 150, 200 MeV's. ...
Convolution/superposition (C/S) is regarded as the standard dose calculation method in most modern radiotherapy treatment planning systems. Different implementations of C/S could result in significantly different dose distributions. This paper addresses two major implementation issues associated with collapsed cone C/S: one is how to utilize the tabulated kernels instead of analytical parametrizations and the other is how to deal with voxel size effects. Three methods that utilize the tabulated kernels are presented in this paper. These methods differ in the effective kernels used: the differential kernel (DK), the cumulative kernel (CK) or the cumulative-cumulative kernel (CCK). They result in slightly different computation times but significantly different voxel size effects. Both simulated and real multi-resolution dose calculations are presented. For simulation tests, we use arbitrary kernels and various voxel sizes with a homogeneous phantom, and assume ...
Current methods to calculate dose distributions with organ motion can be broadly classified as 'dose convolution' and 'fluence convolution' methods. In the former, a static dose distribution is convolved with the probability distribution function (PDF) that characterizes the motion. However, artifacts are produced near the surface and around inhomogeneities because the method assumes shift invariance. Fluence convolution avoids these artifacts by convolving the PDF with the incident fluence instead of the patient dose. In this paper we present an alternative method that improves the accuracy, generality as well as the speed of dose calculation with organ motion. The algorithm starts by sampling an isocenter point from a parametrically defined space curve corresponding to the patient-specific motion trajectory. Then a photon is sampled in the linac head and propagated through the three-dimensional (3-D) collimator structure corresponding to a particular MLC segment chosen randomly from ...
The ODS superalloys MA 6000 and MA 760 were investigated with regard to their behaviour under non-isothermal fatigue stress. For this purpose, strain-controlled thermomechanical and bithermal experiments with different phase relationships between strain and temperature were carried out on the one hand; on the other hand, the deformation behaviour under thermomechanical stress was modelled on the basis of isothermal cyclic creep data. The fatigue experiments show that a diamond-shaped cycle derived from the stress pattern of a turbine blade is clearly less critical than in-phase and out-of-phase cycles. The life of the diamond-shaped cycle is determined by oxidation-induced crack initiation and propagation and can be predicted easily with a suitable damage model. Important damage parameters required by the model can be obtained by the less complicated bithermal fatigue tests. Modelling of the TMF hystereses suggests that cyclic, non-isothermal deformaltion is determined mainly by ...
To test the assumption underlying every morphometric twin study that the brains of monozygotic twins are almost identical. Methods: High resolution MRI of the neurocranium of 26 monozygotic twin pairs were acquired and the volumes of 36 cerebral structures were measured. The same twins served as control group after rear-ranging them into non-related pairs of same sex and matching them for age, body height and body weight. Results: For most of the examined structures the correlations within the twins were significant (R = 0,97-0,59). Except for total forebrain volume the controls showed no significant similarity. Conclusions: For almost every measured cerebral structure the assumption, that significant similarities exist between healthy monozygotic twins is correct. Therefore discordant monozygotic twins represent an excellent sample when investigating cerebral correlates of neurologic and psychiatric disorders. (orig.) [German] Pruefung der Grundannahme hirnmorphologischer ...
Several components of high-temperature reactor units have roller bearings in order to carry out their motions without much friction. The use of such bearings poses friction and wear problems which cannot be mastered by commercial roller bearing technology. Possible improvements of coating, cage design and bearing materials as well as of their parameters were registered and studied. The service life of dry lubricated bearings was considerably improved. With a radial or axial load on the bearing of {>=} 10% of the static load, {approx_equal} 20x10{sup 6} rolling motions/actuations can be performed. The connections between surface compression and wear were determined, and optimum conditions for the transfer of lubricants from the cage onto the bearing race were worked out. Coating of corrosion-resistant roller bearing steels with the HRB-M{sub 0}S{sub 2} running-in coating could be proved. New cage designs and materials were tested with positive results. Alternative coatings (thin ...
To study the biogeochemical behaviour, mobility and transport of trace metals in seawater (Se, Mo, Cd, Pb, Hg, Cu, Co, Fe, Ni, Zn), in suspended particulate matter (Mo, Cd, Pb, Cu, Co, Fe, Ni, Zn, Al, Mn) and in sediments of the inner and outer coastal regions, samples were collected on 3 separate cruises during a one year period (Mai 1993 - April 1994) at 20 stations in the coastal area of Mecklenburg-Vorpommern. Standard hydrographic parameters, nutrients and dissolved oxygen were also measured. Priority was taken to establish the methods for the determination of molybdenum and selenium. To study the behaviour of these two elements in detail, longterm measurements were carried out weekly between January 1993 and June 1994 at the `Messsteg/Warnemuende`. Because of parallel measurements correlations to biological, chemical and hydrographic parameters have been tested. The total database is summarized in the Appendix. The results are presented in 30 figures and 13 tables and are ...
1. Cyanide degradation: Of the cyanide- and thiocyanate-degrading bacteria, Burkholderia cepacia and Pseudomonas spec. were the most effective. 2. Biosorption: Of the isolates suited for biosorption of heavy metals, 597-A (non-identifiable) and 597-A2 (Aspergillus fumigatis) had the biggest potential. The sorption capacity of the fungi for metals varied with the C source used for their growth: apple juice > molasses > glucose. The fungi are not cyanide-sensitive and can even degrade cyanide. Living biomass had better metal sorption efficiencies than dead mycelium. The biosorption rates in waste water were usually higher than in broth. Depending on the metal composition and concentrations and on the exposure time and volume of the mycelia, up to 85 % of the initial concentration was removed from the liquid phase. The capacity of different biomasses for the sorption of metal mixtures was between 65 and 80 mg/g of dry matter depending on the experimental conditions, with ...
The nuclear structure of A {proportional_to} 100 nuclei has been studied in the frame of this thesis with a recently developed {beta} - {gamma} - {gamma} triple coincidence fast timing technique and different models such as shell model, hydrodynamic model, Nilsson and particle-rotor models. This technique which allows the measurement of the level lifetimes in the ps range has been applied at JOSEF at the research reactor DIDO of KFA Juelich in studes of the short-lived neutron-rich nuclei in the A {approx_equal} 100 region. Lifetimes of level in {sup 96},{sup 98},{sup 100} ZR, {sup 99},{sup 101}-{sup 104} Nb, {sup 100}-{sup 105} Mo have been measured, which are in many cases completely new, and otherwise more precise than previously published data. From the lifetimes of the members of rotational bands, the size of the nuclear deformations has been deduced. (orig./HSI). [Deutsch] Im Rahmen dieser Doktorarbeit wurde die Kernstruktur der A {proportional_to} 100 Kerne untersucht. Dazu ...
Aim: The purpose of this prospective study was to evaluate the value of immunoscintigraphy (ISG) with anti-225.28S in clinically suspected ocular melanoma. Methods: For this purpose standardized ISG was performed in 36 patients using both planar acquisition and emission computed tomography (ECT). Ocular melanoma was present in 31 patients. In 21 patients therapy was enucleation of the eye. These specimens were evaluated by histology and immunohistochemistry in 11 of 21 patients. Results: Regarding the clinical diagnosis, ISG was positive only in 15 of 31 patients with ocular melanoma, regarding histology in 11 of 21 and regarding immunohistochemistry in 5 of 6 patients with a positive immunoreaction. 5 patients showed no immunoreactivity, their ISG was negative. Conclusion: Thus a good correlation between ISG and immunohistochemistry was observed. However ISG using the cutaneous melanoma antibody 225.28S cannot be recommended for the diagnostic work-up of an ocular melanoma considering ...
To determined precisely a possible connection between the amount of copper in tap-water and the risk of early childhood liver disease, it was attempted through an epidemiological survey, to determine the extent of excessive concentrations of copper in the tap-water of households with copper pipes. Water samples from 956 households were tested for copper, and the state of health of the infants in these households was documented. Infants who had been fed using water with a copper concentration of 0.8 mg/l or more received a paediatric examination with a blood serum analysis to rule out any liver damage. A copper level greater than 0.8 mg/l was found in only 2% of the households examined. Eight infants were examined by a paediatrician and their serum was analysed. These infants had either been breast-fed to the 12th week or had received more than 200 ml of tap water per day during first 12 months. None of the infants examined showed any signs of liver malfunction. From the results of the ...
The influence of a decarburisation process during austenitising of the through-hardenable rolling bearing steel 100Cr6 (SAE 52100) on the rim zone properties of the martensitic through-hardened material was investigated by means of material analysis and diffusion calculations. For this purpose, two specimens were prepared under defined heat treatment conditions, and the near-surface carbon distribution was determined micro-chemically by using secondary ion mass spectrometry (SIMS). In part 1 of the present work, these concentration profiles are compared with the depth variation of the micro-hardness and with the distance curves of the residual stresses and the line broadening ({l_brace}211{r_brace} {alpha}'-Fe diffraction line) both measured by X-ray diffraction (XRD). In addition, microstructure investigations were performed. In part 2, a refined kinetics model of a diffusion-controlled reaction based on the finite element method (FEM) will be applied to the decarburisation ...
Purpose: The nint version of the licensing regulation for medical doctors (Approbation Regulation (AR)) sets a benchmark in terms of practical experience, interdigitation of preclinical and clinical studies, interdisciplinary approach, economic efficiency, independence of students, added new teaching and learning modalities, and ongoing evaluation of the progress of the medical students. It is the aim to implement these major points of the AR in a model course for diagnostic radiology and radiation protection within the scope of the Virtual University of Bavaria and test them in practice. Materials and Methods: In cooperation with residents and board certified radiologists, students developed the virtual course 'Web-Based Training (WBT) Radiology' in diagnostic radiology and radiation protection for students in the first clinical semester. A representative target group taken from the student body was asked about the options to get access to the World Wide Web ...
Backgrund: Interleukin-1, tumornecrosisfactor-{alpha} and interferon-{gamma} endogenously provide protection of the hematopoietic system against radiation. Thiols have already been used successfully as radioprotective agents. In this study the effect von N-acetylcysteine (NAC) on the release of interleukin-1{alpha} and {beta} (IL-1), interleukin-2 (IL-2), interferon-{gamma} (IFN-{gamma}) and tumornecrosisfactor-{alpha} (TNF-{alpha}) was assessed in an in vitro assay. Patients and Methods: Whole blood samples from 8 healthy volunteers were stimulated with 7.5 {mu}m/ml PHA. NAC was added at concentrations of 0.6, 6, 12 and 24 mmol/l. Subsequently the samples were irradiated with a dose of 18 Gy according to preceding validation experiments. Results: IL-1{alpha}, IL-1{beta} and IL-2: In comparison to simulation and radiation alone the addition of 0.6 and 6 mmol/l with IL-2 also 12 mmol/l, NAC resulted in a significant increase of the cytokine-concentrations. The highest concentration of ...
Purpose: The purpose of this study was to observe the process of fixation in liver specimens non-invasively by means of magnetic resonance. The fixation process of several formaldehyde-containing solutions was monitored with MRI and MRS at two different temperatures. Materials and Methods: Liver specimens were conserved in aqueous fixative solutions containing formaldehyde concentrations of 0.7, 1.8, 4 and 7.2% and at different temperatures of 5 C and 20 C. MRI was performed with T1-, T2- and PD-weighted TSE sequences, a 2D FLASH-sequence with and without magnetization transfer, and a FISP 3D-sequence on a clinical 1.5 Tesla MR whole-body unit, and MRS with {sup 1}H-spectroscopic methods (STEAM-sequence) on a 3 Tesla MR whole-body unit. Results: The diffusion of formaldehyde into the tissue was best identified on PD- and T1-weighted images as a band under the liver surface with increasing thickness, penetrating especially fast during the first three days. Spectroscopic measurements ...
The first volume of the report covers the state of implementation of primary and secondary measures for SO{sub 2}- and NO{sub x} control applied in the most important industrial sectors in Germany. Integrated pollution abatement techniques, called primary measures in this report, such as process integrated measures and low emission processes, have gained increased importance in recent years. The end-of-pipe processes, described here as secondary measures, are generally highly effective. They represent mature technologies, which are capable of achieving significant reductions in SO{sub 2}- and NO{sub x} emissions, and which have been used in particular for retrofitting existing plants. At first, an overview is given regarding the development of SO{sub 2}- and NO{sub x} emissions in selected European countries during the last 20 years and in Europe. Current national and European emission limits and emission guidelines on SO{sub 2}- and NO{sub x} emissions from stationary sources are ...
Objective: To determine the efficacy of a covered stent prototype designed for protected carotid angioplasty to reduce cerebral embolization. Material and Method: The covered stent tested is made of nitinol, coated with a polyurethane membrane (MembraX{sup TM}; porous size 80 {mu}m). In a bench-top model (flow-rate 650 ml/min, pulsatile flow [dicrote] 123 Pulses/min, pressure 100/60 mm Hg [mean pressure 80 mmHg]) with inserted human carotid (n=6) stent implantation was performed (8/32 mm). Passed particles (mg) were determined in the effluent of a 100 {mu}m filter prior to intervention, after stent deployment and after final dilation (5 mm). Results: When stenting carotid arteries obtained from human cadavers, the highest rate of particle embolization was measured while crossing the lesion with the delivery device (6,8 mg; for all p<0,05), embolization after additional balloon angioplasty and particle rates measured in the effluent filter prior covered stent placement were ...
Wood is currently having a renaissance as a domestic fuel. Wood pellets, usually about 8 mm in diameter and 40 mm long and produced from sawmill and wood processing residues by pressing without binders, are gaining general acceptance. According to a market analysis of Solar Promotion GmbH, Pforzheim, about 4,800 pellet-fuelled heating systems with automatic fuel supply and with a total thermal capacity of 35 kW are in operation in Germany, and 2000 new ones were installed in 2000. [German] Holz als Brennstoff erlebt in vielen Heizkellern und Kaminen eine Renaissance. Und zwar nicht in Form von Holzscheiten, sondern als kleine Presslinge, meist mit einem Durchmesser von acht und einer Laenge von bis zu 40 Millimetern. Als Abfallprodukt von Saegewerken und Holz verarbeitenden Betrieben werden die so genannten Pellets unter hohem Druck und ohne Bindemittel wie beispielsweise Leim hergestellt. Und dieser neue Brennstoff findet immer mehr Anhaenger. So sind im ...
The RCP method was designed as a residue-optimised alternative to the thermally optimised grate firing of residual wastes. Its technical realisation and development to market maturity took no more than 5 years. In the first process stage the waste is converted to high-carbon pyrolysis charcoal and high-rank gas in the absence of oxygen. In the second stage these substances are oxidised by addition of oxygen. The resulting temperature causes the non-combustible constituents of the slag to melt. In a third, optional, stage this molten slag can be liberated of (heavy) metals to such an extent that it can subsequently be used directly as additive for grinding. Further exhaust gas treatment is facilitated by the use of a circulatory fluidised-bed secondary combustion chamber. Despite the reduced flue gas volume and resultant higher pollutant concentrations in the crude gas, overall emissions are lower than in conventional plants. [Deutsch] Das reststoffoptimierte RCP Verfahren ist als ...
When performing trenchless pipe renovation work - whichever process you use - the success of the job depends on the careful removal of all scale, sediments and rust from the innerwall surfaces. The VACUJET process - in which the pipe is cleaned with water at pressures of up to 2 500 bar using a technique jointly developed by Preussag Rohrsanierung GmbH and Fabex GmbH - meets all requirements. The equipment includes a mobile waste water treatment unit which is small enough to fit on a standard trailer. Despite its compact dimensions this plant is so effective that it can treat all the waste water generated during the high pressure cleaning jobs so that it is suitable for reuse in the cleaning process or for release into the sewerage system. (orig.) [Deutsch] Bei der grabenlosen Rohrsanierung, ganz gleich nach welchem Verfahren saniert wird, ist die sorgfaeltige Entfernung von alten Beschichtungen, Ablagerungen und Rost eine wesentliche Voraussetzung fuer den Sanierungserfolg. Das ...
The paper addresses the major items of relevance to compensation for nuclear damage under civil liability law. The revision of the Vienna Convention deserves support as a contribution to enhancing the protection of those who suffered damage, and of the environment. The results of the revision will have an impact on the liability regimes in existing and future signatory states, and to some extent will also set the goals of a future reshaping of the Paris Convention, all the more since the Joint Protocol calls for harmonization of at least basic provisions of substantive law in the two Conventions. (orig./HP) [Deutsch] Es werden die wesentlichen Punkte dargestellt, die fuer die zivilrechtliche Praxis im Schadensfall von Belang sein koennten. Die Revision ist als Beitrag zu einem verbesserten Schutz Geschaedigter, aber auch der Umwelt zu begruessen und zu unterstuetzen. Die Ergebnisse werden sich auf die Rechtsordnungen der gegenwaertigen und zukuenftigen ...
The objective of the project was to develop an infiltration material based on SiC that should have improved corrosion resistance and should permit higher operating temperatures. From a variety of tested doping agents, zirconium silicide and molybdenum proved to be the most appropriate agents. The respective infiltration materials permit a combination of advantages of the SSiC with those of the SiSiC. Silicide SiC, analogous to the SiSiC, is almost nonshrinking, and above all is more corrosion-resistant than SiSiC in the alkaline regime, due to the replacement of free silicon by silicide phases. The operating temperature of the molybdenum-base variant is 1600 C. (orig./CB) [Deutsch] Ziel des Vorhabens war die Entwicklung eines Infiltrationswerkstoffes auf SiC-Basis mit verbesserter Korrosionsbestaendigkeit und hoeherer Einsatztemperatur. Aus einer Vielzahl von getesteten Dotierungsmoeglichkeiten kristallisierten sich Zirkondisilicid und Molybdaen als geeingete Zusaetze heraus. Die ...
In a case study of the River Lahn, Hessen, Germany, the ecological impact of effluents from sewage treatment plants was investigated. These emissions have a significant impact on the receiving water quality with ammonia, nitrite, phosphorus and the eutrophication as most important factors. Current legislation standards seem to be sufficent for the sanitation of the nitrogen load. The potential of phosphorus removal in sewage treatment plants however may not reach the demand for eutrophication abatement. Therefore, integrated and immission oriented strategies are required including in site measures of river restoration. (orig.) [Deutsch] An der hessischen Lahn wurde in einem mehrjaehrigen Forschungsvorhabens die Bedeutung von Abwasserereinleitungen aus Klaeranlagen hinsichtlich ihrer gewaesseroekologischen Relevanz untersucht. Wesentliche Belastungen beziehen sich auf die Parameter Ammonium, Nitrit und Phosphor sowie eutrophierungsbedingte Folgeerscheinungen. ...
As one of the largest contractors for the construction of ethylene plants featuring steam cracker furnaces as their core component Linde AG has examined the `real` chemical recycling of polymers in steam cracker furnaces as an alternative to their thermal utilisation. In steam cracker furnaces the feedstock, i.e., hydrocarbons, is broken down to ethylene, propylene, and other valuable products in a steam dilution of approx. 800-870 C. In the ideal case, if polyolefins are used as feedstock, then the initial product which led to the polymers can be fully recycled. In this context a series of experiments was carried out in a laboratory-scale cracker plant. The purpose of this was to demonstrate the technical feasibility and the economic advantage of using recycling polyethylene or polypropylene as feedstock for steam cracker plants. (orig./SR) [Deutsch] Die Linde AG als einer der bedeutendsten Kontraktoren fuer den Bau von Ethylenanlagen, deren Herzstueck die Steamcrackeroefen sind, hat ...
Only about 25% of residue accumulating in the Federal Republic of Germany is currently used for the purposes of energy. This residue will be converted into fuel for power stations by the Omega process when the dumping of waste with a calorific value in excess of 5 MJ/kg is prohibited with effect from 2005. This oxygen melting process is suitable for the local use of substitute fuels. Waste is converted into a high-quality synthesis gas with a wide range of uses. The Omega process combines drying, thermal decomposition, gasification and melting of the material used in a single-stage process. This is now technologically possible for the first time by combining a metallurgical cupola furnace with a traditional gas producer. The highly-calorific synthesis gas produced by the Omega process can be used in block heat and power stations or as an industrial fuel gas, instead of natural gas. It is also suitable as a starting material for synthesising methanol. The gas is specifically processed ...
As an alternative to the usual way of installing wind machines in extended windfarms new concepts are being developed. Several wind turbines are affixed to one support structure and can be aligned together. Drafts of steel constructions developed by students in three diploma theses are presented. The attempt to transform existing design standards requires extensive discussion of possible influence scenarios. Several concepts regarding structure and safety elements are described and evaluated. The design of the support structure is to be seen as a first step to the practicability of the whole concept. A preliminary mass calculation and a specification of further cost factors facilitates the comparison to conventional wind power stations. (orig.) [Deutsch] Als Alternative zur ueblichen Praxis, Windenergieanlagen in Form grossflaechiger Windparks zu bauen, werden Konzepte entwickelt, bei denen mehrere Konverter an einem Tragwerk angeordnet und gemeinsam in den Wind ...
More than two and a half years of monitoring of a passive house school and day-care centre in Frankfurt a. M. show comfortable indoor climate and good air quality. The space heat consumption is low and shows savings of approximately 90 % as compared to average existing schools. Excellent performance was also achieved in terms of primary energy. The results of further analyses of the efficient ventilation system with heat recovery, the perimeter insulation as an alternative to floor slab insulation and the influence of the air change due to the entrance door are presented. (Abstract Copyright [2008], Wiley Periodicals, Inc.) [German] Ueber zweieinhalb Jahre Monitoring einer Passivhaus-Schule und Kindertagesstaette (KiTa) in Frankfurt a.M. zeigt behagliche raumklimatische Bedingungen bei guten Luftqualitaeten. Die Heizwaermeverbrauchswerte liegen wie erwartet niedrig und zeigen Einsparungen um 90 % gegenueber dem Durchschnitt im Bestand. Auch primaerenergetisch bewertet, weist die Schule ...
The Mittelplate oilfield is located in the Waddensea tidelands 8 km off the north sea coast and represents Germany's largest oilfield. Since Mittelplate oil production has started in 1987, RWE Dea AG being the operator in a 50/50 joint venture with Wintershall AG, has continually implemented and improved the sophisticated technology required to exploit natural resources by using safe and environmentally compatible means in the sensitive tideland environment of Mittelplate. Besides the sucessful offshore operations from the man-made Mittelplate Drilling and Production Island, further onshore development has started in 2000 by producing from high-tech ERD wells drilled from onshore locations. The offshore oil production had been transported so far by specially designed tug and tow barges and had been restricted by weather and tide. To overcome this bottleneck and to enable an accelerated offshore drilling and production program a pipeline link between Mittelplate Island and ...
Nitriding leads to improved tribological and corrosive properties of iron alloy components. In order to study the effect of plasma nitriding parameters on the structure of compound layer and diffusion zone, a systematic variation of process parameters, temperature and process gas atmosphere has been carried out. Metallographic inspection, X-ray diffraction and glow discharge optical spectroscopy analysis (GDOES) were used in this investigation. The results clarified that depending on the amount of nitrogen in the gas atmosphere nitrided layers with and without compound layer can be generated in the surface of M2 tool steel for temperatures from 350 C to 500 C. For plasma nitriding in 5 vol.% Nitrogen and 95 vol.% Hydrogen no compact compound layer was formed. The gas mixture of 76 vol.% Nitrogen resulted in compound layer formation for all temperatures from 350 C to 500 C. X-ray phase analysis indicated an almost 100% {epsilon}-(carbo)nitride phase but the existence of the ...
About 25 years after the last edification of a new large high voltage institute at Technical University of Karlsruhe and about 10 years afte the edification of the test lab at Kaiserslautern University, the Brandenburg Technical University of Cottbus had the opportunity to design new high voltage test facilities from the very beginning on and to realize it in a very short time. To review the project from the first ideas followed by the planning and realization phase and the final commissioning of the technical equipment, this book should be a contribution to spred the experiences made among interested people and to demonstrate the actual technical possibilities. To ensure an international exchange of these experiences, all co-authors to the trouble to translate their participation's also to the English language. (orig.) [German] Etwa 25 Jahre nach dem letzten grossen hochspannungstechnischen Institutsneubau in der deutschen Hochschullandschaft an der TH Karlsruhe, bzw. 10 ...
A high-temperature flow reactor and different technical plants were tested within the framework of this research project. Anthropogenic N{sub 2}O emissions form during secondary flue gas or waste gas purification as secondary emissions during denitrification and pollution abatement measures. N{sub 2}O forms as an intermediate product as NO is reduced to N{sub 2}. Under certain operating conditions N{sub 2}O is not decomposed completely. Different secondary flue gas purification measures, i.e. selective noncatalytic reduction (SNCR), selective catalytic reduction (SCR), and nonselective catalytic reduction (NSCR) were investigated testing several technical plants and the high-temperature flow reactor. (orig./EF) [Deutsch] Das Forschungsprojekt ``Messung der N{sub 2}O-Emissionen von Verbrennungsanlagen und Untersuchung von Moeglichkeiten zur Emissionsminderung`` wurde an einem Hochtemperatur-Stroemungsreaktor und an verschiedenen technischen Anlagen durchgefuehrt. ...
The ash of biomass fuels was analysed in order to identify its inorganic chemical characteristics. The experiments were carried out using different methods of extraction. The accuracy of the measurements was verified by comparative analyses using certified samples. The composition was shown to vary with the fuel type and ash fraction. In the case of arsenic and the toxic heavy metals cadmium, mercury and lead, accumulation factors of 1.4 to 43 were measured in the tissue filter ash. [German] Fuer die Bestimmung der stofflichen Eigenschaften von Biobrennstoffaschen werden neben der fuer die Ermittlung von Stoffbilanzen notwendigen Analyse der Gesamtgehalte, in Abhaengigkeit von der Zielsetzung und den gesetzlichen Vorgaben, unterschiedliche Extraktionsverfahren eingesetzt. Fuer die Gesamtgehaltsbestimmung wurden aus laborinternen Wiederholungsuntersuchungen sowie einem laborexternen Analysenvergleich Kenngroessen fuer die Praezision und Richtigkeit abgeleitet. ...
In an extended case report, we discuss four cases with masses in the lacrimal fossa representing the most important entities in this region (lymphoma, pleomorphadenoma, inflammatory pseudotumor, and malignant epithelial tumor). The different indications for CT and MRI are explained. For the differential diagnosis of lacrimal gland lesions, the following imaging parameters are important: The shape of the lacrimal gland, the inner structure, the degree of contrast enhancement, and the surrounding bony structures. In the evaluation of the expansion of lacrimal gland lesions, CT in thin slices with multiplanar reconstructions is equal to MRI. However, the contrast-enhancement of lacrimal glands is better evaluated with MRI than with CT. The bony structures are better visualized on CT than on MRI. (orig.) [Deutsch] In einem erweiterten Fallbericht wird ueber die vier grossen Entitaeten bei Traenendruesenraumforderungen berichtet (Lymphom, pleomorphes Adenom, ...
Large-eddy-simulations are performed for the heat transfer and the wake flow of a thin rotating disk subjected to an outer parallel passing stream of air. Above a critical value for the angular velocity of the disk, heat transfer augmentation sets on. This is strongly related to a flow instability that leads to a periodic vortex generation at the counter-moving disk side. The resulting phenomena are captured by the classical Landau model. For higher angular velocities the wake becomes fully turbulent, and here the transition to turbulence seems to be very abrupt. In this regime, a periodic vortex generation is observable at the co-moving disk side, too. (orig.) [German] Grobstruktur-Simulationen werden fuer die Waermeuebertragung und die Nachlaufstroemung fuer eine duenne rotierende Scheibe in einem aeusseren parallelen Luftstrom durchgefuehrt. Oberhalb eines kritischen Wertes fuer die Rotationsgeschwindigkeit setzt eine Verstaerkung der Waermeuebertragung ein. ...
A process model is presented and used for identifying options for controlling the cupola furnace process and for investigating natural gas substitutes. Fuel substitution will affect temperature curves (i.e. tapping temperatures and melting capacity), outlet temperatures and gas mass flow out of the preheating zone. The contribution presents several process variations to overcome these problems and compares them with the natural gas process. [German] Mit dem Prozessmodell werden zunaechst Moeglichkeiten der Steuerung von Abstichtemperatur und Schmelzleistung, insbesondere unter Beruecksichtigung der Schrottqualitaet (spezifische Oberflaeche a{sub G}), untersucht. Es wird gezeigt, dass das Prozessmodell die Ergebnisse aus der Praxis wiedergibt. Daran anschliessend wird mit dem Prozessmodell die Substitution von Erdgas durch minderwertige Gase untersucht (Brennstoffsubstitution, Ressourcenschonung). Durch die Brennstoffsubstitution veraendern sich die Temperaturverlaeufe und damit auch ...
Molybdenum is an essential element for living organisms. Moreover its radionuclides may represent an incorporation risk for members of the public and/or radiation workers after a nuclear accident or a release of radioactive materials. However, only few reliable data on Mo biokinetics in humans were available. The results of recent tracer kinetic investigations with stable isotopes have shown several differences from the ICRP data with regard to the processes of intestinal absorption and of excretion. As a consequence, the dose coefficients calculated with a revised biokinetic model deviate from the ICRP estimates. By ingestion of {sup 99}Mo radionuclides with solid food, for example, the dose to the colon may be higher of a factor up to 1 order of magnitude, due to the fraction of non-absorbed material which traverses the gastro-intestinal tract. (orig.) [Deutsch] Molybdaen ist einerseits ein fuer Lebewesen essentielles Spurenelement, andererseits koennen radioaktive Mo-Isotope im ...
The enhancements described of high-performance CT systems of latest design have again confirmed the importance of CT systems for acute and selective diagnostic imaging. Higher availability, shorter exposure times, and better applicability and handling for examination of poly-traumata patients or patients of intensive care departments are some of the advantages achieved with CT systems which demonstrate CT system efficiency in addition to MRI, which for specific examinations will remain the modality of first choice for diagnostic evaluation. The Tomoscan Av-E presented here was able to answer all relevant diagnostic questions appearing in routine diagnostics and scientific work. For patients, examinations using the spiral CT technique also offers significant advantages. (orig./CB) [Deutsch] Durch die dargestellten Verbesserungen bei Hochleistungs-CT-Systemen neuester Bauart wurde die Bedeutung der CT fuer die akute und selektive Diagnostik erneut bestaetigt. Bessere Verfuegbarkeit, ...
The externally fired combined cycle (EFCC) process utilises a high temperature heat exchanger to transfer the heat of a dirty flue gas to a clean working medium. In comparison to other combined cycle concepts, like integrated gasification combined cycle or pressurized pulverized coal combustion, the problems of hot gas cleaning are avoided. The first part of the publication (BWK 5/02) deals with the possible concepts and the efficiency potential of the externally fired combined cycle. The applicability of metallic and ceramic heat exchanger materials are discussed. The second part summarizes the state of the art and presents the basic design of a ceramic heat exchanger. [German] Der extern gefeuerte Gasturbinenprozess arbeitet mit einem Waermeuebertrager, um ein Arbeitsmedium auf Gasturbineneintrittstemperatur zu erhitzen. Im Vergleich zu Kombiprozessen mit integrierter Kohlevergasung oder Druckkohlenstaubfeuerung entfaellt damit die Heissgasreinigung. Der erste ...
The externally fired combined cycle (EFCC) process utilises a high temperature heat exchanger to transfer the heat of a dirty flue gas to a clean working medium. In comparison to other combined cycle concepts, like integrated gasification combined cycle or pressurized pulverized coal combustion, the problems of hot gas cleaning are avoided. The first part of the publication deals with the possible concepts and the efficiency potential of the externally fired combined cycle. The applicability of metallic and ceramic heat exchanger materials are discussed. The second part (BWK 6/02) summarizes the state of the art and presents the basic design of a ceramic heat exchanger. (orig.) [German] Der extern gefeuerte Gasturbinenprozess arbeitet mit einem Waermeuebertrager, um ein Arbeitsmedium auf Gasturbineneintrittstemperatur zu erhitzen. Im Vergleich zu Kombiprozessen mit integrierter Kohlevergasung oder Druckkohlenstaubfeuerung entfaellt damit die Heissgasreinigung. Der ...
Gel dosimetry is a new dosimetry method applied in radiation therapy. Gel dosimeters consist of a radiation sensitive gel, which can integrate absorbed doses from several radiation sources or beams. The dose to the gel can be evaluated by magnetic resonance imaging (MRI), a procedure that is the focus of the present thesis. A robust tool for the evaluation of the nonuniformity in MRI has been developed, the Deviation Image method. Unlike previously presented methods, the Deviation Image method includes all nonuniformity variations across a phantom surface and is insensitive to stochastic noise. Methods for the estimation of stochastic noise were analyzed in terms of sensitivity to nonuniformities. A method that averages the stochastic noise level over five regions over the phantom surface, and a method that assesses the stochastic noise level from the background, were found to be the methods of choice. Pronounced MR image nonuniformity ...
Full text: A semiempirical algorithm for absorbed dose calculation at off-axis points in irregular beams was implemented. It is well known that semiempirical methods are very useful because of their easy implementation and its helpfulness in dose calculation in the clinic. These methods can be used as independent tools for dosimetric calculation in many applications of quality assurance. However, the applicability of such methods has some limitations, even in homogeneous media, specially at off axis points, near beam fringes or outside the beam. Only methods derived from tissue-air-ratio (TAR) or scatter-maximum-ratio (SMR) have been devised for those situations, many years ago. Despite there have been improvements for these manual methods, like the Sc-Sp ones, no attempt has been made to extend their usage at off axis points. In this work, a semiempirical formalism was introduced, based on the works of Venselaar et al. (1999) and Sanz et al. (2004), aimed to the Sc-Sp separation. This ...
A number of procedures in diagnostic radiology and cardiology make use of long exposures to x-rays from fluoroscopy units. Although numerous studies have been performed to measure or calculate skin dose from these procedures, there have only been a handful of studies to determine the dose to the other organs. This thesis was focused on devising a method to calculate the absorbed dose to underlying tissues and organs. The work was performed in several stages. First, a commercial convolution/superposition-based treatment planning system used in radiation oncology was modified and complemented to make it usable with the low energies of x-rays used in diagnostic radiology. This required generation of energy deposition kernels in the kilovoltage energy range. The kernels were generated using the EGS4 Monte Carlo system of codes and added to the treatment planning system. The treatment planning system was then evaluated for its accuracy of calculations at low energies within homogeneous and ...
Background: In an effort to standardise radiological practices in the Republic of Ireland, current legislation states that 'written protocols for every type of standard radiological practice shall be established'. In order to fulfil this requirement the Irish Medical Council recommends the protocols issued by the Commission of European Communitees (CEC) for adoption in the country. Whilst this document does provide good guidance with regard to various radiographic factors, patient shielding instructions are notably ambiguous. The aim of this study was to remove some of this ambiguity by defining the optimal method of positioning patient shielding in antero-posterior (AP) and lateral lumbar spine radiographic examinations. These projections were chosen on the basis of their area of coverage being in close to and in some cases including the reproductive organs. They also represent the highest source of collective population dose of any conventional radiographic ...
Background: In an effort to standardise radiological practices in the Republic of Ireland, current legislation states that 'written protocols for every type of standard radiological practice shall be established'. In order to fulfil this requirement the Irish Medical Council recommends the protocols issued by the Commission of European Communitees (CEC) for adoption in the country. Whilst this document does provide good guidance with regard to various radiographic factors, patient shielding instructions are notably ambiguous. The aim of this study was to remove some of this ambiguity by defining the optimal method of positioning patient shielding in antero-posterior (AP) and lateral lumbar spine radiographic examinations. These projections were chosen on the basis of their area of coverage being in close to and in some cases including the reproductive organs. They also represent the highest source of collective population dose of any conventional radiographic examination carried out in ...
To determine a suitable combination of X-ray filter and tube kilovoltage for Fuji Computed Radiography (FCR), provide better detection of pulmonary nodules, and reduce patient exposure, we compared observer performance with different X-ray filters and tube voltages. Radiographs were obtained with a copper filter backed by aluminium, with a tungsten filter backed by yttrium and aluminium, and with a lead filter backed by yttrium and aluminium, at both 100 kVp and 135 kVp. Observer performance in detecting simulated lung nodules, which were placed on the posterior aspect of a chest phantom, was compared using receiver operating characteristic (ROC) techniques for each combination of the X-ray filter and tube voltage. The results of the study indicated that (1) nodule detection was superior for the images obtained with 135 kVq as compared with 100 kVp; (2) approximately equal detection rates were obtained for the three X-ray filter sets, although results with the ...
To determine a suitable combination of X-ray filter and tube kilovoltage for Fuji Computed Radiography (FCR), provide better detection of pulmonary nodules, and reduce patient exposure, we compared observer performance with different X-ray filters and tube voltages. Radiographs were obtained with a copper filter backed by aluminium, with a tungsten filter backed by yttrium and aluminium, and with a lead filter backed by yttrium and aluminium, at both 100 kVp and 135 kVp. Observer performance in detecting simulated lung nodules, which were placed on the posterior aspect of a chest phantom, was compared using receiver operating characteristic (ROC) techniques for each combination of the X-ray filter and tube voltage. The results of the study indicated that 1) nodule detection was superior for the images obtained with 135 kVq as compared with 100 kVp; 2) approximately equal detection rates were obtained for the three X-ray filter sets, although results with the ...
The risks of genetic, leukemia and malignant diseases from medical X-ray diagnostic examinations were estimated using the frequency of radiographic and fluoroscopic exposures per diagnostic examination, child expectancy, leukemia and malignancy significant factors, and using a weighting factor determined on the basis of data concerning the cancer mortality among atomic bomb survivors in Nagasaki and of a recommendation of International Commission of Radiological Protection. The organ or tissue doses with respect to the stochastic risks were determined with ionization chambers and thermoluminescent dosimeters placed at the positions of the organs or tissues in a RANDO woman phantom which was exposed to diagnostic X-rays according to technical factors of typical radiographic and fluoroscopic examinations obtained from a nationwide survey. The resultant risks by age-group and type of radiographic and fluoroscopic examination are tabulated in terms of risk level of ...
Late plagiogranite bodies in the Semail ophiolite have been previously suggested to represent late stage fractionates within an episodic spreading center magma chamber or the roots of seamount chains. Field and lab observations suggest that these late silicic magma chambers represent zones of repeated injection by dikes of intermediate to mafic composition. Multiple generations of intrusion, partial resorption and reintrusion are preserved in the plagiogranite as 1) relict phantom xenoliths, 2) angular xenoliths with quartz-rich margins, 3) deformed fine-grained dikes with distinct chilled margins, and 4) planes of rectangular blocks with cuspate margins or ellipsoids of similar fine grained mafic materials. The blocks and ellipsoids are actually dismembered mafic dikes that chilled by intruding a cooler silicic liquid and were either thermally fractured or pinched out. All of the dikes are hydrothermally altered to assemblages including amph., qtz., epi., preh., ...
The patients studied were referred for routine abscess localization with indium-111 labelled autologous leukocytes. One series (n=15) was studied at 1 day after reinjection of labelled cells and a second series (n=9) was studied between 4 hours and 4 days after reinjection of labelled cells. The leukocytes were isolated by a gravity sedimentation method and labelled with In-111 oxinate according to Roevekamp and co-workers. The labelled cell suspension administered to the patient contained between 11 and 15 MegaBq (300-400 microCi). The indium-111 concentration in the liver and spleen was quantitated using a scintillation camera and an on-line computer system. Phantom studies were carried out to obtain conversion factors from geometric mean counts to MegaBq of activity for both liver and spleen. Once determined, the amount of activity in liver and spleen was corrected for physical decay of In-111 and expressed as a percentage of the administered activity. ...
It has been five years since the last in-depth American College of Nuclear Physicians/Society of Nuclear Medicine Symposium on the subject of single photon emission computed tomography (SPECT) was held. Because this subject was nominated as the single most desired topic we have selected SPECT imaging as the basis for this year's program. The objectives of this symposium are to survey the progress of SPECT clinical applications that have taken place over the last five years and to provide practical and timely guidelines to users of SPECT so that this exciting imaging modality can be fully integrated into the evaluation of pathologic processes. The first half was devoted to a consideration of technical factors important in SPECT acquisition and the second half was devoted to those organ systems about which sufficient clinical SPECT imaging data are available. With respect to the technical aspect of the program we have selected the key areas which demand awareness and attention in order ...
{sup 188}Re is a {beta}{sup -} (Emax=2.12 MeV) and {gamma} (155 keV) emitter. Since its chemistry is similar to that of the largely employed tracer, {sup 99m}Tc, molecules of hyaluronic acid (HA) have been labelled with {sup 188}Re to produce a target specific radiopharmaceutical. The radiolabeled compound, i.v. injected in healthy mice, is able to accumulate into the liver after a few minutes. To study the effect of metabolic radiotherapy in mice, we have built a small gamma camera based on a matrix of YAP:Ce crystals, with 0.6x0.6x10 mm{sup 3} pixels, read out by a R2486 Hamamatsu PSPMT. A high-sensitivity 20 mm thick lead parallel-hole collimator, with hole diameter 1.5 mm and septa of 0.18 mm, is placed in front of the YAP matrix. Preliminary results obtained with various phantoms containing a solution of {sup 188}Re and with C57 black mice injected with the {sup 188}Re-HA solution are presented. To increase the space resolution and to obtain two orthogonal ...
As a series of estimations of population doses and of risk estimates from medical exposures in Japan, the malignancy significant dose (MSD) and the fatal malignant risk from beam therapy were estimated based on a nationwide survey of radiotherapeutic treatments, using a malignancy significant factor and a weighting factor determined from the data on the cancer mortality among the atomic bomb survivors in Nagasaki. The effective dose was defined as a sum of the product of the weighting factor and the organ or tissue doses with respect to the malignant diseases. The organ or tissue doses were determined with ionization chambers placed at the positions of their center in a MixDp-phantom simulated lung tissues by a block of cork, using a telecobalt unit, a conventional X-ray unit and a medical linear accelerator. The organ or tissue doses were categorized into three dose components; namely 1) dose from useful beams; 2) scattered radiation dose from irradiated materials ...
To evaluate the diagnostic performance of commercially available CRT monitors used in a teleradiology system by determining the rate of detection of simulated lung nodules. Three types of CRT monitors were tested in the observation study. They had matrix sizes of 1024 x 768 (16 inches, color), 1024 x 768 (20 inches, color) and 1600 x 1125 (24 inches, black and white). Twenty chest radiographs were obtained by Fuji computed radiography (FCR) of an anthropomorphic chest phantom with ten simulated nodules on its surface. These FCR films were digitized by a film digitizer with 125 DPI (1024 x 1024 matrix sizes) and 12 bit gray scales, and the image data were transferred from Shinshu University Hospital to other hospitals where interpretation was carried out by the radiologists. Ten radiologists of three hospitals were asked to interpret independently both the original FCR films and the images shown on the CRT monitors and to indicate the presence or absence of ...
Accurate modeling of system response and scatter distribution is crucial for image reconstruction in emission tomography. Monte Carlo simulations are very well suited to calculate these quantities. However, Monte Carlo simulations are also slow and many simulated counts are needed to provide a sufficiently exact estimate of the detection probabilities. In order to overcome these problems, we propose to split the simulation into two parts, the detection system and the object to be imaged (the patient). A so-called 'virtual boundary' that separates these two parts is introduced. Within the patient, particles are simulated conventionally. Whenever a photon reaches the virtual boundary, its detection probability is calculated analytically by evaluating a multi-dimensional B-spline that depends on the photon position, direction and energy. The unknown B-spline knot values that define this B-spline are fixed by a prior 'pre-' simulation that needs to be run once for each scanner type. After ...
Brachytherapy refers to short distance treatment of cancer with radiation from small, encapsulated radionuclide sources. This type of treatment is given by placing sources directly into or near the volume to be treated. The dose is then delivered continuously, either over a short period of time (temporary implants) or over the lifetime of the source to a complete decay (permanent implants). This technique is extensively used in the treatments of gynecological, breast, prostate, head and neck, and other soft tissue cancers. The clinical outcomes of this treatment depend on accurate dosimetry and dose delivery. The patient is generally considered to be water equivalent. So the treatment planning system software generally is based on measured or calculated dose distributions in homogenous water medium. In real situation, the treatment volume is not homogenous water medium, but it is a heterogeneous medium consisting of bone, soft tissue, lung, air etc. For better understanding we present ...
During the last few decades, accuracy in photon and electron radiotherapy has increased substantially. This is partly due to enhanced linear accelerator technology, providing more flexibility in field definition (e.g. the usage of computer-controlled dynamic multileaf collimators), which led to intensity modulated radiotherapy (IMRT). Important improvements have also been made in the treatment planning process, more specifically in the dose calculations. Originally, dose calculations relied heavily on analytic, semi-analytic and empirical algorithms. The more accurate convolution/superposition codes use pre-calculated Monte Carlo dose 'kernels' partly accounting for tissue density heterogeneities. It is generally recognized that the Monte Carlo method is able to increase accuracy even further. Since the second half of the 1990s, several Monte Carlo dose engines for radiotherapy treatment planning have been introduced. To enable the use of a Monte Carlo treatment planning (MCTP) dose ...
For Monte Carlo simulations to be used as an alternative solution to perform scatter correction, accurate modelling of the scanner as well as speed is paramount. General-purpose Monte Carlo packages (Geant4, EGS, MCNP) allow a detailed description of the scanner but are not efficient at simulating voxel-based geometries (patient images). On the other hand, dedicated codes (SimSET, PETSIM) will perform well for voxel-based objects but will be poor in their capacity of simulating complex geometries such as a PET scanner. The approach adopted in this work was to couple a dedicated code (SimSET) with a general-purpose package (Geant4) to have the efficiency of the former and the capabilities of the latter. The combined SimSET+Geant4 code (SimG4) was assessed on the GE Advance PET scanner and compared to the use of SimSET only. A better description of the resolution and sensitivity of the scanner and of the scatter fraction was obtained with SimG4. The accuracy of scatter correction ...
Monte Carlo simulation of beam modifiers such as physical wedges and compensating filters has been performed with a rectilinear voxel geometry module. A modified version of the EGS4/DOSXYZ code has been developed for this purpose. The new implementations have been validated against the BEAM Monte Carlo code using its standard component modules (CMs) in several geometrical conditions. No significant disagreements were found within the statistical errors of 0.5% for photons and 2% for electrons. The clinical applicability and flexibility of the new version of the code has been assessed through an extensive verification versus dosimetric data. Both Varian multi-leaf collimator (MLC) wedges and standard wedges have been simulated and compared against experiments for 6 MV photon beams and different field sizes. Good agreement was found between calculated and measured depth doses and lateral dose profiles along both wedged and unwedged directions for different depths and focus-to-surface ...
In radiotherapy treatment planning, convolution/superposition algorithms currently represent the best practical approach for accurate photon dose calculation in heterogeneous tissues. In this work, the implementation, accuracy and performance of the FFT convolution (FFTC) and multigrid superposition (MGS) algorithms are presented. The FFTC and MGS models use the same 'TERMA' calculation and are commissioned using the same parameters. Both models use the same spectra, incorporate the same off-axis softening and base incident lateral fluence on the same measurements. In addition, corrections are explicitly applied to the polyenergetic and parallel kernel approximations, and electron contamination is modelled. Spectra generated by Monte Carlo (MC) modelling of treatment heads are used. Calculations using the MC spectra were in excellent agreement with measurements for many linear accelerator types. To speed up the calculations, a number of calculation techniques were implemented, ...
The aim of this work was to develop several strategies and software-packages for the evaluation of in-vivo-data of the human brain, which were acquired with high-resolution 1H-MRSI at 1.5 and 3 T. Several studies involving phantoms, volunteers and patients were performed. Quality assurance studies were conducted in order to evaluate the reproducibility of the applied MR-techniques at both field strengths. A qualitative comparison-study between MRSI-data from a 1.5 T clinical MR-scanner and a 3 T research MR-scanner showed the advantages of the more advanced MRSI sequences and higher field strength (3 T). A study involving patients with primary brain tumours (gliomas) was performed in cooperation with the Department of Neurosurgery (University of Erlangen-Nuremberg). The methods developed in the course of this study, such as the integration of MRS-data into a stereotactic-system, the segmentation of metabolic maps and the correlation with histopathological findings ...
Analytical expressions that describe the dependence of slopes and amplitudes of the scatter distribution functions (SDF) on source depth and media density are used to estimate a scatter component in SPECT projection data. Since the ratio of detected scattered to total photons (S/T), SDF amplitude and slope depend strongly on line source length (SL) used to obtain SDFs, we compared estimated scattered components using SDFs, obtained for lengths of 2-21 cm. At 10 cm source depth, S/T changes from 0.19 to 0.36 when SL changes from 2 to 21 cm. Scatter amplitude`s dependence on source depth (d) in water was described by 6.38e{sup -0.186d} for a 2 cm and 16.15e{sup -0.129d} for a 21 cm SL. Slope was described by 0.292d{sup -0.601} for a cm SL and by 0.396d{sup -0.82} for a 21 cm SL. The estimated scatter components are compared with simulated SPECT projection data obtained with Monte Carlo modeling of six hot spheres placed in a cylindrical water filled phantom. The ...
Collective dose equivalent and population dose from occupational exposures in Japan, 1988 were estimated on the basis of a nationwide survey. The survey was conducted on annual collective dose equivalents by sex, age group and type of radiation work for about 0.21 million workers except for the workers in nuclear power stations. The data on the workers in nuclear power stations were obtained from the official report of the Japan Nuclear Safety Commission. The total number of workers including nuclear power stations was estimated to be about 0.26 million. Radiation works were subdivided as follows: medical works including dental; non-atomic energy industry; research and education; atomic energy industry and nuclear power station. For the determination of effective dose equivalent and population dose, organ or tissue doses were measured with a phantom experiment. The resultant doses were compared with the doses previously calculated using a chord length technique and ...
Collective dose equivalent and population dose from occupational exposures in Japan, 1988 were estimated on the basis of a nationwide survey. The survey was conducted on annual collective dose equivalents by sex, age group and type of radiation work for about 0.21 million workers except for the workers in nuclear power stations. The data on the workers in nuclear power stations were obtained from the official report of the Japan Nuclear Safety Commission. The total number of workers including nuclear power stations was estimated to be about 0.26 million. Radiation works were subdivided as follows: medical works including dental; non-atomic energy industry; research and education; atomic energy industry and nuclear power station. For the determination of effective dose equivalent and population dose, organ or tissue doses were measured with a phantom experiment. The resultant doses were compared with the doses previously calculated using a chord length technique and ...
We measured and evaluated digital, pre-sampling and overall imaging properties (characteristic curve, modulation transfer function (MTF), Wiener spectrum (WS), noise equivalent quanta (NEQ)) for Cannon's flat-panel detector (FPD), Fuji computed radiography (FCR) and screen-film (S/F) systems, respectively. First, the digital and overall characteristic curves of FPD and FCR systems were more wide dynamic range than that of the S/F system. Second, the pre-sampling and overall MTF of FPD system were better than those of FCR system a little at lower spatial frequencies than 0.8 mm"-"1, but the overall MTF of FPD and FCR systems were worse than that of S/F system a little at all spatial frequencies. Third, the digital and overall WS of FPD system were similar or better than those of FCR system, but the overall WS of FPD and FCR systems were worse than that of S/F system. Fourth, the pre-sampling and overall NEQ of FPD system were better than those of FCR system a little at lower spatial ...
We measured and evaluated digital, pre-sampling and overall imaging properties (characteristic curve, modulation transfer function (MTF), Wiener spectrum (WS), noise equivalent quanta (NEQ)) for Cannon's flat-panel detector (FPD), Fuji computed radiography (FCR) and screen-film (S/F) systems, respectively. First, the digital and overall characteristic curves of FPD and FCR systems were more wide dynamic range than that of the S/F system. Second, the pre-sampling and overall MTF of FPD system were better than those of FCR system a little at lower spatial frequencies than 0.8 mm{sup -1}, but the overall MTF of FPD and FCR systems were worse than that of S/F system a little at all spatial frequencies. Third, the digital and overall WS of FPD system were similar or better than those of FCR system, but the overall WS of FPD and FCR systems were worse than that of S/F system. Fourth, the pre-sampling and overall NEQ of FPD system were better than those of FCR system a little at ...
Boron Neutron Capture Therapy (BNCT) is a promising binary treatment modality for high-grade primary brain tumors (glioblastoma multiforme, GM) and other cancers. BNCT employs a boron-10 containing compound that preferentially accumulates in the cancer cells in the brain. Upon neutron capture by {sup 10}B energetic alpha particles and triton released at the absorption site kill the cancer cell. In order to gain penetration depth in the brain Fairchild proposed, for this purpose, the use of energetic epithermal neutrons at about 10 keV. Phase I/II clinical trials of BNCT for GM are underway at the Brookhaven Medical Research Reactor (BMRR) and at the MIT Reactor, using these nuclear reactors as the source for epithermal neutrons. In light of the limitations of new reactor installations, e.g. cost, safety and licensing, and limited capability for modulating the reactor based neutron beam energy spectra alternative neutron sources are being contemplated for wider implementation of this ...
A cross sectional study on the mineral density of the 3rd lumbar vertebral trabecular bone was carried out in 123 children less than 15 years old, comprising 44 controls, and 79 patients affected with conditions which are at risk for developing metabolic derangement of skeletal bone (34 patients taking antiepileptic drugs (AED), 29 undergoing glucocorticoid (GC) therapy and 16 bedridden patients), by using quantitative computed tomography (QCT) with a CaCO{sub 3} phantom. Serum Ca and alkaline-phosphatase (Alp) levels were measured at the time of QCT examinations in all. The results obtained were as follows: The QCT values in the control children showed neither age dependency nor a sexual difference before puberty. The QCT values in each group showed significant difference with one another; the control group>the AED group>the GC group>the bedridden group (p<0.05{approx}0.005). The serum Ca levels in each pathology group were significantly lower than ...
During the last decade, new radiopharmaceutical have been introduced for brain imaging. The marked differences of these tracers in tissue specificity within the brain and their increasing use for diagnostic studies support the need for a more anthropomorphic model of the human brain and head. Brain and head models developed in the past have been only simplistic representations of this anatomic region. For example, the brain within the phantom of MIRD Pamphlet No. 5 Revised is modeled simply as a single ellipsoid of tissue With no differentiation of its internal structures. To address this need, the MIRD Committee established a Task Group in 1992 to construct a more detailed brain model to include the cerebral cortex, the white matter, the cerebellum, the thalamus, the caudate nucleus, the lentiform nucleus, the cerebral spinal fluid, the lateral ventricles, and the third ventricle. This brain model has been included within a slightly modified version of the head ...
During the last decade, new radiopharmaceutical have been introduced for brain imaging. The marked differences of these tracers in tissue specificity within the brain and their increasing use for diagnostic studies support the need for a more anthropomorphic model of the human brain and head. Brain and head models developed in the past have been only simplistic representations of this anatomic region. For example, the brain within the phantom of MIRD Pamphlet No. 5 Revised is modeled simply as a single ellipsoid of tissue With no differentiation of its internal structures. To address this need, the MIRD Committee established a Task Group in 1992 to construct a more detailed brain model to include the cerebral cortex, the white matter, the cerebellum, the thalamus, the caudate nucleus, the lentiform nucleus, the cerebral spinal fluid, the lateral ventricles, and the third ventricle. This brain model has been included within a slightly modified version of the head ...
Purpose: To develop an accurate, fast, and robust algorithm for registering portal and computed tomographic (CT) images for radiotherapy using a combination of sparse and dense field data that complement each other. Methods and Materials: Gradient Feature Weighted Minimax (GFW Minimax) method was developed to register multiple portal images to three-dimensional CT images. Its performance was compared with that of three others: Minimax, Mutual Information, and Gilhuijs' method. Phantom and prostate cancer patient images were used. Effects of registration errors on tumor control probability (TCP) and normal tissue complication probability (NTCP) were investigated as a relative measure. Results: Registration of four portals to CTs resulted in 30% lower error when compared with registration with two portals. Computation time increased by nearly 50%. GFW Minimax performed the best, followed by Gilhuijs' method, the Minimax method, and Mutual Information. Conclusions: ...
Nickel base superalloys for turbine construction are exposed to maximum thermal and mechanical stresses. owing to a change of materials by one of the project partners, the project only comprised analyses of the alloy CMSX-6. Isothermal tensile and fatigue tests provided basic data on the alloy. Thermomechanical fatigue tests showed that material life and microstructural changes are clearly, and to an extreme extent, dependent on the type of combination of the two stress factors `temperature interval` and `total strain amplitude`, while the damage to the material tends to be a function of the maximum stresses for a given stress path. On the one hand, these results make it possible to obtain information real stresses from the structures of real blades. On the other hand, constructional measures can be taken in order to better adapt the stresses to which alloys are exposed to their characteristic potential. (orig./AKF) [Deutsch] Die im Turbinenbau eingesetzten Nickelbasis-Superlegierungen ...
Poly-Lactic-Acid (PLA) was evaluated for coating of vascular endoprotheses in the treatment of experimental arterio-venous-fistulae (AVF). Bilateral carotid-external jugular AVF were created in 5 adult dogs. 7 PLA coated nitinol stents were placed via a transfemoral approach covering 5 AVF. The contralateral AVF remained untreated. Angiography was performed immediately after stent placement, at weeks 1 and 3 and at months 3, 6 and 9. All grafts were removed and underwent histologic examination. In 2 cases the occlusion of the AVF was successful, while misplacement occurred in 3 cases. Occlusion of the parent vessel was disclosed in 3 cases. Histologic examination revealed a mild inflammatory reaction with the presence of macrophages. There was no foreign-body reaction or fragmentation of the arterial vessel wall. PLA, which is a well-known biodegradable material, showed a good mid-term biocompatibility. Elastic mismatch of the non-elastic coating and the self-expandable nitinol stent ...
The oxidation of boron carbide in steam or air was recently extensively studied especially in Forschungszentrum Karlsruhe, Institut fuer Materialforschung. An important data set is available for the interaction modelling. An oxygen diffusion model through the superficial liquid boron oxide formed on the boron carbide external surface associated to a superficial reaction between the liquid boron oxide and steam is proposed to simulate the experimental kinetics from BOX rig and thermogravimetric tests on the interaction between steam and boron carbide at a temperature range 800 C to 1400 C. The oxygen diffusion model will be also useful to simulate interaction between boron carbide and Ar+O2 (air simulation) atmosphere when the steam pressure becomes zero. From the analysis of BOX rig experimental kinetics of non-condensable (H2, CO2, CO and CH4) gases we propose an oxygen diffusion model through the liquid boron oxide and a ''steam/liquid boron ...
Aim: Changes within the brain detected by MRI after chronic manganese poisoning raised the question whether morphological changes of the basal ganglia, particularly of the globus pallidus, could be detected after chronic occupational exposure to manganese dioxide. Results: No cases of parkinsonism were detected in clinical examinations or by other means. The mean manganese concentration in blood was 12 {mu}g/l (range: 3.9-23.3 {mu}g/l). In comparison to the upper reference value of 10 {mu}g/l, 42 workers (56%) had a higher body burden. A significant positive correlation between manganese levels in blood and the PI (indicated by T{sub 1}-shortening) was observed as well as between the CBI and workplace-specific exposure. Brain atrophy was not detected in any of the observed cases. Conclusions: Long-term exposure to manganese dioxide dust correlates with the Pallidum-Index in MRI scans. Although the MRI findings have no current clinical relevance for individuals, further studies are ...
Austenitic stainless steel (18% Cr, 12% Ni, Mo gradation between 0,06 to 3,6%) had been solution nitrided. By step-by-step removing, the samples could be prepared with various surface contents of nitrogen from 0.04 to 0.42%. In two test series the influence of nitrogen had been determined. The susceptibility against pitting corrosion of these samples had been tested by the chronopotentiostatical method. For the investigated steel composition and the used corrosion system there is no influence of molybdenum on the effectiveness of nitrogen. The effectiveness of nitrogen can be described by the factor 25 in the PRE. By the investigation of the surfaces with the XPS analysis, it could be shown that the passivation and the pit nucleation is influenced by nitrogen. In these ranges NO{sub x}, NH{sub x}, and NH{sub z}-spectra have been detected. Bound Mo was found in steels containing molybdenum. It is assumed that the repassivation mechanisms of N and Mo work independently of each other. ...
Purpose: The aim of this study was to demonstrate the typical appearance of ganglioneuromas in computer-assisted tomography (CT), and magnetic resonance imaging (MRI). Material and methods: Retrospective analysis of diagnostic imaging (9 CT, 6 MRI) in 9 children aged 3 to 15 years with the histological diagnosis of ganglioneuroma. Results: The tomographies showed large (max. 13.4 cm in diameter) round or oval tumors with sharp delineation. The sites of the tumors were the retroperitoneum (5), the mediastinum (3), and the adrenal gland (1). Intraspinal tumor involvement occurred in 4 cases. On comparing CT with MRI, MRI was more accurate in defining the intraspinal involvement. The ganglioneuromas were of hypodense appearance in the native CT scan and showed moderate enhancement upon administration of contrast media. In five patients tumor calcifications with a disseminated sprinkled pattern were seen in CT. In MRI T{sub 1}-weighted scans the tumors were homogeneous and hypointense, ...
1. In order to carry out isothermic crystal growth experiments of YBCO the 123 primary crystallization field was determined by means of phase diagram investigations and crystal growth experiments at different oxygen partial pressure. 2. YBCO single crystals of high crystallographic perfection were grown and conclusions on the flux pinning mechanism were drawn. 3. By means of Liquid Phase Epitaxy (LPE) single crystalline (Tc{approx}90 K; {Delta}T{<=}0.5 K) c- and a,b- YBCO fils have been prepared on NdGaO{sub 3} and LaGaO{sub 3} substrates. The films were characterized structurally and magnetically. 4. Our fist melt textured YBCO ``single crystals`` possess intracrystalline critical current densities >10{sup 4} A/cm{sup 2} at B{<=}2T. The irreversibility inductions are {<=}6 T at 77 K. A simple demonstrator was constructed together with the IFW Dresden and a growth model was developed. 5. Using above all torque magnetometer measurements we separated intrinsic pinning effects ...
Purpose: For planning the therapeutic strategies and estimating the prognosis in esophageal cancer, N-staging is very important. To date, MRI still is of minor importance as imaging modality of the mediastinum despite promising developments in the past, like ECG-gating or 'averaging' sequences, e.g. LOTA (Long-term averaging), which facilitate mediastinal and thoracic MR-imaging. In a prospective approach, the value of MRI based N-staging was examined with respect to LOTA-sequences. Material and Methods: Within from weeks prior to esophagectomy, standardized MRI of the esophagus was performed in 15 patients (10 squamous-cell-carcinomas and 5 adenocarcinomas) using a 1.5 T whole body scanner. Imaging quality was classified based on depiction of aortic wall or tracheal wall layers. Criteria for malignant infiltration were a diameter of more than 15 mm or a round appearance of a lymph node together with GD-DTPA enhancement. All data were blinded and separately read by ...
The Deutsche Post AG is a transport company that with approximately 55,000 vehicles owns one of the biggest fleets in Europe. Being aware of its responsibility in the field of environmental policy it is looking for an alternative solution of an environmentally friendly vehicle drive system that also takes into account economic efficiency. Extensive investigations have led to a new energy storage based on the zinc-air energy system that has been developed and manufactured by the Israeli Company Electric Fuel Ltd. First tests showed an extraordinarily high capacity potential, drive values and ranges, which had been considered as impossible until that point of time. After these tests the Deutsche Post AG decided together with other well-known partners at home and abroad to carry out a territorial test with the zinc-air energy system in order to obtain insight into the day-to-day capability, economic efficiency, environmental friendliness under real driving conditions and into the required ...
The ECOTEC is a mass-efficient gasoline DOHC 4-valve per cylinder engine with balance shafts, chain driven camshafts and roller finger followers with hydraulic lash adjusters for valve actuation. It has lightweight aluminium components such as camcover, cylinder head, cylinder block, lower crankcase and structural oil pan. Other features include composite intake manifold and a coil-on-plug ignition cassette. The ECOTEC combustion system and engine architecture are optimized for low engine out and tail pipe emissions. It also includes several designed-in 'green' features for environmental benefits. The product design, development and validation process drew upon the best knowledge and practices available worldwide both inside and outside General Motor. The manufacturing systems were also designed by leveraging the best available knowledge around the world resulting in implementation of world class processes and error proofing to achieve the competitive edge in product ...
DMT has developed what is called the stepped reforming process. This is an allothermal gasification process which uses hydrogen for a gasification medium. First the biomass is pyrolised by means of a heat transfer material. The escaping gaseous and condensable constituents are hydrogenated, heated in a reforming stage and are made to react to a hydrogen-rich product gas by means of homogeneous gasification. The heat required for this is provided by burning the pyrolysis coke. This makes it possible to dispense with process stages that would involve gasification of solid material and hence require higher pressure levels. The present process also works at ambient pressure. Moreover, stepped reforming promises a number of additional advantages: low-tar product gas containing 60% hydrogen, high cold gas efficiency, no wastewater arisings, robust operating behaviour. This paper outlines the basic ideas that led to the development of stepped reforming process and describes its diverse ...
One part of the RWE measure catalogue in order to guarantee an environmental friendly and competitive electric power generation based on brown coal is to carry out measures improving the efficiency at existing steam turbines in RWE brown coal power plants. Since 1993 a total of 21 steam turbines with a gross capacity of 7,100 MW or net capacity of 6540 MW - this corresponds to approximately 70 % of the installed RWE brown coal power plant capacity - have been improved with an investment of approximately DM 500 million. The net block efficiency has been increased by 1.3 % on average. The planned net capacity increase of approximately 250 MW is still going to be achieved taking into account the pending enhancements. Nuclear power plant turbines have been successfully improved in the same way. Apart from the described retrofit programme measures to improve efficiency are carried out at further steam turbines of brown coal power plants. In the frame of this talk the measures taken are ...
Objective: Optimization and testing of a high temperature combustion chamber for burning coal gas and conventional fuels natural gas or fuel oil. Coal gas is not available in such quantity for testing a full scaled combustion chamber. Therefore the design of the combustion chamber is based of experimental results from model tests and numerical solution procedures. Working program: (1) Analytical model for burning coal gas implemented in an existing computational fluid dynamics (CFD) code. (2) Three-dimensional calculations of a full scaled combustion chamber with a CFD code for flows accompanied by combustion and chemical reaction. (3) Improvement of measuring method for determination of flame temperature and concentration. (4) Temperature and concentration profil measuring in a full scaled combustion chamber by operating with natural gas or fuel oil. Results: An analytical model for burning coal gas was implemented in an existing two-dimensional CFD code. The model gave acceptable ...
Lung cancer staging according to the TNM system is based on morphological assessment of the primary cancer, lymph nodes and metastases. All aspects of this important oncological classification are measurable with MRI. Pulmonary nodules can be detected at the clinically relevant size of 4-5 mm in diameter. The extent of mediastinal, hilar and supraclavicular lymph node affection can be assessed at the same time. The predominant metastatic spread to the adrenal glands and spine can be detected in coronal orientation during dedicated MRI of the lungs. Search focused whole body MRI completes the staging. Various additional MR imaging techniques provide further functional and clinically relevant information during a single examination. In the oncological context the most important techniques are imaging of perfusion and tumor motion. Functional MRI of the lungs complements the pure staging and improves surgical approaches and radiotherapy planning. (orig.) [German] Das Staging des ...
The paper discusses multiaxial, isothermal and thermocyclic experiments with tubes made of the austenitic steel 1.4909 (AISI 316 L(N)). The thermocyclic stress is induced by periodic, inductive heating of the tube outer wall and simultaneous, continuous water cooling of the inner wall. Temperature gradients above 100 K/mm are measured, which cause fatigue cracking, predominantly in the inner wall. The experiments with the isothermally stressed tube specimens are intended to simulate the equi-biaxial stress conditions that are typical of the thermocyclic stress regime. This stress regime is created by superimposed longitudinal stress (tension/compression), and circumferential stress (internal/external compression). A novel test bench was realised specifically for the experiments. The paper explains design, operation, and measuring techniques, especially of the circumferential strain measurements. The measured results are compared with results of uniaxial strain cycling experiments made ...
In comparison to deterministic criteria, probabilistic reliability indices like interruption frequency and unavailability give a more differentiated insight into reliability in an electrical energy network. One possibility for network planning based on these indices is the definition of limits for customer nodes, another is the monetarisation of reliability in terms of interruption costs. Because of numerous disadvantages, interruption cost methods could not up to now win broad recognition in network planning in Western Europe. A more recent method for the monetarisation of reliability circumventing most of these disadvantages is the insurance system. In this system the customer selects a tariff class in an insurance system, and the utility reimburses its customers in the case of an interruption. In its first section, the paper describes a method for the flexible and realistic optimisation of MV networks. This method based on Genetic optimisation is able to integrate probabilistic ...
A procedure is described for the isolation and determination of {sup 90}Sr, {sup 226}Ra, {sup 228}Ra and {sup 210}Pb in food. These nuclides are highly radiotoxic, above all for babies and children. Samples are dry ashed, alkali metals are removed as carbonates. Separation from other matrix ions and separation of Ra, Sr and Pb can be achieved with a column of Sr-Spec, an immobilized crown ether. For activity measurements membrane filters with SrSO{sub 4}, Ba(Ra)SO{sub 4} and PbS are prepared. Ra is determined by gamma-spectrometry, {sup 90}Sr and {sup 210}Pb are determined by low-level-betacounting. The determination limits are 10 mBq/kg for {sup 90}Sr and {sup 210}Pb and 50 mBq/kg for {sup 226}Ra and {sup 228}Ra. The procedure is useful for all kinds of foodstuff. (orig.) [Deutsch] Es wird ein Analysengang zur Abtrennung und Bestimmung von {sup 90}Sr, {sup 226}Ra, {sup 228}Ra und {sup 210}Pb in Lebensmitteln beschrieben. Ein Merkmal dieser Nuklide ist ihre hohe Radiotoxizitaet, ...
The main objective of nuclear liability law is the compensation of victims of a possible nuclear incident. However, an adequate nuclear liability law is just as important for nuclear industry, in particular the supply industry - including suppliers of know-how and consultants. Without such a law, the liability risk would be incalculable and industry would not be ready to supply to nuclear installations or nuclear activities. This applies especially to programmes which aim at improving nuclear safety in Eastern Europe. Key elements are the exclusive concentration of liability onto the operator of a nuclear installation (channelling of liability) and the channelling of lawsuits onto one single competent court in one single country. There are recent examples: The negotiations on the management of nuclear waste, including submarines, in Northern Russia and the negotiations within the framework of the East Asian project of the Korean Peninsula Energy Development Organization (KEDO), ...
The influences of temperature and duration of tempering on hardness and microstructure were investigated at high-temperature martensitic and low-carbon steels with 9% chrome and the further alloying elements molybdenium, vanadium, niobium and partially tungsten. After austenitizing and subsequent air cooling the steels were tempered at temperatures below, at and above Ac{sub 1b} for different times and finally a hardness test was performed. Making use of the temperature dependence of the hardness tempering diagrams were constructed and the Hollomon-Jaffe-Parameter on the three steels was determined within its application limits. Micrographs of the structure shows the formation of the carbides and the martensite. At tempering temperatures below Ac{sub 1b} a decrease of hardness occurs, above Ac{sub 1b}, a hardness rise due to the partial austenitizing was obtained. While hardening below Ac{sub 1b}, the tempering quality increases from P 91, NF 616 to E 911. (orig.) [Deutsch] An ...
The aim of this review is to evaluate the role of inflammatory spine disease in patients with chronic back pain. The contribution of imaging modalities for the diagnostic evaluation of back pain is discussed. A systematic literature search based on the classification of seronegative spondyloarthropathies and rheumatoid arthritis was performed. The results of this search and the experiences in a large collective of rheumatological patients are analyzed. The prevalence of rheumatoid arthritis (1-2%) is comparable to that of spondyloarthropathies (1.9%). The etiology of these entities is not fully elucidated. Magnetic resonance imaging is increasingly used for early detection and surveillance of therapy with TNF-{alpha} antagonists. Bone marrow edema, which is only detectable with MRI, represents an early sign of inflammation. Therapy with TNF-{alpha} antagonists is based on clinical and laboratory criteria, and signs of inflammation in MRI. MRI is useful for assessment of the ...
The first commercial vehicle, built by Gottlieb Daimler in Cannstatt (Germany), head foto, had been the begin of a new transport technology around the world. Benz had been consolidated 1926 with Daimler to the Daimler-Benz AG with a new vehicle programme; all trucks over 5 t payload would be powered since 1935 by diesel engines only. Worldwide all-wheel drived vehicles had been under development for different purposes. After 1945 the European Automobil industry launched at first former types followed by new designed and improved types. The eight-wheeler used since the twentees in England conquered Switzerland, and in 1984 Germany too. The development of gear boxes and drive axles had been influenced on the drive train demands depending of the engine output and speed and the increased GTW. The future of the commercial vehicles will be determined by the European legislation, higher economy and reduced-pollutant Euro II and later Euro III engines, further by the cooperation of the truck ...
Already in 1998, the city of Hanover, the Stadtwerke Hannover and six further cities of the region initiated the funding programme 'Hannover proKlim' for promoting energy-relevant modernization measures in domestic buildings. One year later, the social marketing campaign 'Haus-Partner Hannover / Der (H)Eissbaer'' was started, which addresses building owners in Hanover with the intention to induce them to action. The 'Energiepass Hannover' is another important instrument of the campaign. This report takes stock of the results achieved so far. [German] Beim Klimaschutz im Gebaeudebestand lassen sich in Hannover drei Ansaetze hervorheben, die parallel zueinander entwickelt wurden und die in besonderer Weise dazu beitragen, die CO{sub 2}-Emissionen im Gebaeudebestand zu reduzieren: Bereits 1998 hat die Landeshauptstadt Hannover gemeinsam mit den Stadtwerken Hannover und sechs weiteren Staedten der Region den Klimaschutz-Fonds ...
For a wider application of GaAs single crystals for semiconductor devices a cheaper process to grow crystals with high purity and low dislocation density is required. According to todays knowledge the Czochralski method with a hot wall vessel should be the choice. The temperature of the vessel has to be 700deg C to avoid condensation of arsenic which vapourizes from the 1240deg C hot melt. Arsenic vapour is very agressive against all metals. Therefore the corrosion resistance of metals and alloys with a high melting point and also ceramics has been tested. All the alloys under investigation are corroded severely so that they have to be excluded as a material for the vessel. The metals tantalum, molybdenum and tungsten are more resistent, titanium forms initially a thick protection layer and further corrosion is greatly reduced. The ceramics investigated (TiB{sub 2}; ALN; Makor; BN) are not attacked by arsenic though they may store some arsenic. (orig./MM). [Deutsch] Fuer breitere ...
The paper presents fundamental studies on natural biosorption to algae of heavy metals. The investigations were carried out by TU Berlin University in a special research project (Sfb 193, 'Biologische Behandlung industrieller und gewerblicher Abwaesser'). The chlorophyceae C. vulgaris was used as reference alga, and 38 further algae were analzyed with regard to their sorption characteristics for lead, cadmium, nickel and zinc. The most effective algae were the chlorophyceae C. salina, the cyanophyceae S. hofmani and L. taylorii. The biosorption characteristics of C. salina and L. taylorii were investigated in detail. L. taylorii was found to be exploitable successfully in a technical process, so the investigations were extended to include copper. Knowledge about the chemical processes of biosorption is important for any attempt to modify the biosorption characteristics. Experiments on the incorporation of additional functional groups in the cell wall polysaccharides ...
A comparative process can be shown for the design of combined fuel cell powerstations. It is worth noting that the output of a combined powerstation working reversibly is independent of the thermodynamic state of the cell, and only depends on the reaction and thermodynamic state of the environment. The potential efficiency of gas-fired combined fuel cell powerstations is estimated at 80%. The fuel cell proves to be an isothermal heat source and not an adiabatic fluegas generator. This applies generally for all combustion power processes. Compared with external reforming, the integration of the reforming in the whole process leads to distinct advantages in efficiency if the possibilities of using the waste heat of intermediate thermal power processes are fully exploited. The plant implementation with an SOFC gas turbine process shows that realisation of a relatively simple plant concept leads to efficiencies distinctly above 70%. The enclosure design is of central improtance for the ...
The measuring series was performed from November 1991 through April 1992 in seven drinking-water conditioning plants of the Fichtel mountains area in the north-eastern part of Bavaria, and the results revealed as an annual average a dose of about 1 - 40 WLM. The area of interest is a drinking-water catchment area where the ground water and other water resources include waters particularly rich in radon content, which explains this relatively high dose range. This is why comprehensive, specific local and long-term mearurements were carried out in order to assess the occupational radiation dose in the drinking-water conditioning plants, taking as a model site the conditioning plant of the municipal utilities of Hof in Weissenstadt. These more specific measurements were performed by the Technical Inspectorates (TUeV) of Bavaria and Saxony and the isotope laboratory of Georg-August University of Goettingen in mid-April 1994 (Goettingen University, TUeV Saxonia and Bavaria) and from June ...
This report completes the documentation for the research project 'High Pressure Compressor - Preliminary Design as Basis for the Development of an Efficient and Environmentally Friendly Core Engine' which was funded by the Ministry of Economics of State Brandenburg. The objective of the project is to deliver a preliminary compressor aerodynamic design as well as design studies for an efficient, weight and cost improved compressor. The increase of stage pressure ratio and improved efficiency, whilst stage and blade count is reduced, has been achieved by advanced 3D methods. Compressor stability also at off-design conditions will be retained. The mechanical design focusses on a cost and weight optimised rotor not only for a conventional bladed discs but also for Blish stages. Various options for split casings have been developed and assessed. Alternative vortex reducers based on different design options have been carried out. The results from this project will be ...
To compare the accuracy in the detection and staging of various malignant tumors with high resolution whole-body MRI using parallel imaging with whole-body dual-modality PET-CT. Preliminary results of an interim analysis from a prospective, blinded study are presented, in which 20 patients (mean age 59 years, range 27-77 years) with different oncological diseases underwent whole-body dual modality FDG-PET-CT screening for tumor search or staging in case of confirmed or suspected metastatic disease. All patients also underwent whole-body MRI imaging with the use of parallel imaging (iPAT). High-resolution coronal T1w- and STIR-sequences of 5 body levels with 512 x 512 matrix, axial fast T2w imaging of lung and abdomen (HASTE), contrast-enhanced dynamic and static T1w-sequences of liver, brain, abdomen, and pelvis were performed. Using a 32-channel whole-body MRI scanner (Magnetom Avanto, Siemens Medical Solutions) with a total field of view of 205 cm and free table movement, all ...
This study was conducted to search for the type of technical error in DEXA (dual-energy X-ray absorptiometry) and the effect of error to measurement of BMD. The changes of BMD (g/cm2, T-score) by patients information (Age, Weight, Height, Manopause age) input error and Confirming ROI error were investigated. Using spine phantom, we canned 10 times by age (5, 10), weight (10, 20 kg), height (5, 10 cm), manopause age (5, 10) increase and decrease respectively. Scanning region (L-spine, femur, Forearm) of 10 patients was calculated by changing ROI respectively. Analysis of difference for mean (precision 1%) were carried out. There error of patient information (Age, Weight, Height, Manopause age) was not changed differently. In confirming ROI, the BMD and T-score of L-spine involving T-12 was decreased to 0.063 g/cm2, 0.3 and involving L-5 increased to 0.077 g/cm2, 0.5. In narrowing 1 cm of vertical line of ROI, the BMD and T-score decreased to 0.006 g/cm2, 0.1 and in ...
Purpose: To evaluated artifacts of unexpended stents and to determine their exact position for MR-guided percutaneous transluminal angioplasty using real-time sequences. Materials and Methods: By using an in vitro model, 11 unexpended stents - 9 nitinol, 1 stainless steel, and 1 cobalt alloy - were investigated by MR. Each stent was studied in a vessel-phantom filled with saline solution. Imaging was performed using five different realtime sequences: fast low angle shot (Flash 2D), fast imaging with steady precession (true FISP, FISP, interactive true FISP) and segmented echo planar imaging (seg. EPI). Artifacts of the introducer system and the stent were calculated by four blinded radiologists (scale: 1 - artifacts, making an excellent contribution to visualization; 2 - artifacts, making mainly a contribution to visualization; 3 - artifacts, making no contribution to visualization). Furthermore, an evaluation of the visibility of the tip of the stent-catheter and ...
High-energy ionizing radiation is a prominent modality for the treatment of many cancers. The approaches to electron dose calculation can be categorized into semi-empirical models (e.g. Fermi-Eyges, convolution-superposition) and probabilistic methods (e.g. Monte Carlo). A third approach to dose calculation has only recently attracted attention in the medical physics community. This approach is based on the deterministic kinetic equations of radiative transfer. We derive a macroscopic partial differential equation model for electron transport in tissue. This model involves an angular closure in the phase space. It is exact for the free streaming and the isotropic regime. We solve it numerically by a newly developed HLLC scheme based on Berthon et al (2007 J. Sci. Comput. 31 347-89) that exactly preserves the key properties of the analytical solution on the discrete level. We discuss several test cases taken from the medical physics literature. A test case with an academic ...
The purpose of this study was to test a large sample of different coronary artery stents using four image reconstruction approaches with respect to lumen visualization, lumen attenuation, and image noise in 64-slice multidetector-row computed tomography (MDCT) in vitro and to provide a catalogue of currently used coronary artery stents when imaged with state-of the-art MDCT. We examined 68 different coronary artery stents (57 stainless steel, four cobalt-chromium, one cobalt-alloy, two nitinol, four tantalum) in a coronary artery phantom (vessel diameter 3 mm, intravascular attenuation 250 HU, extravascular density -70). Stents were imaged in axial orientation with standard parameters: 32x0.6 collimation, pitch 0.24, 680 mAs, 120 kV, rotation time 0.37 s. Four different image reconstructions were obtained with varying convolution kernels and section thicknesses: (1) soft, 0.6 mm, (2) soft, 0.75, (3) medium soft, 0.6, and (4) stent-optimized sharp, 0.6. To evaluate ...
This thesis deals with the analysis of dominant loss mechanisms in direct methanol fuel cells (DMFC) and hydrogen fed polymer electrolyte membrane fuel cells (PEFC) by means of experimental characterization and modeling work. Due to different fuels used in these two fuel cell types, the dominant loss mechanisms are different in their nature. All in-situ characterization techniques that are used in this work are based on a novel test fuel cell with embedded reference electrodes. The first part of this work presents a new concept for realizing a reference electrode configuration in a polymer electrolyte membrane fuel cell by means of laser ablation. The laser beam is used to evaporate a small gap into the electrode surface of a catalyst coated membrane (CCM) to isolate the reference electrode from the working/counter electrode (WE/CE). This method enables the simultaneous ablation of the electrodes on both sides of the CCM because the membrane is transparent for the laser beam. ...
The aim of this study was to evaluate typical magnetic resonance imaging (MRI) findings in early rheumatic diseases manifesting at the soft tissues of the hand using a retrospective analysis. A total of 186 MRI examinations of patients with clinical suspicion of a rheumatic disease were evaluated in a consensus reading by two experienced radiologists. All imaging patterns were assessed with respect to their type and localization. Under blinded and non-blinded conditions diagnoses were correlated with final clinical diagnosis. The most frequent diagnoses were rheumatoid arthritis (RA, 45.7%) and psoriatic arthritis (PsA, 15.6%). The mean correlation between clinical and MRI diagnosis (r) was 0.75 in blinded and 0.853 in non-blinded reading (p <0.001). The following extra-articular imaging patterns were found: synovitis (59.1%), tendovaginitis (91.4%), dactylitis (14.5%), and bone marrow edema (18.3%). Only dactylitis was specific for a particular rheumatic disease (PsA; r=0.934; ...
Purpose: An animal model is used to investigate whether MR angiography combined with super-paramagnetic particles of iron oxide (SPIO) is suitable for detecting thromboses. Methods: 42 rats in groups of 7 each were examined on days 1, 3, 5, 7, 9 and 11, respectively, after mechanical/chemical thrombus induction in a 1.5 Tesla magnet with a FISP sequence (TR/TE/FA 50 ms/6 ms/40 ). Imaging was performed before and up to 90 minutes after intravenous injection of 30 {mu}mol FE/kg BW of the experimental SPIO (hydrodynamic diameter, 34{+-}17 nm LLS; R1 and R2 relaxivity at 0.47 T, 31 and 57 L/(mmol*s)). MIP reconstructions of MR angiographies were submitted to consensus assessment by two examiners using histology as the gold standard. Results: The image quality of MIP reconstructions was rated as good in 38 of 42 cases. With regard to thrombotic vessel occlusion, MR angiography coincided with histology in 17 of 42 cases and differed in 25, lumen narrowing being overestimated by MRI in 4 ...
The aim of this work was the examination of the coarse grain recrystallisation of the {gamma}-free ODS nickel-based alloy PM 1000 depending on the various parameters due to the processing during heat treatment. After isotropic hot compacting (HIP) of the mechanically alloyed powder, one observes a homogeneous sub-microscopic fine grain structure which can coarsen during high temperature heat treatment, due to sufficiently high driving force from the grain boundary energy via abnormal grain growth to 600 times its size. The setting of the elongated high temperature resistant recrystallisation structure is, however, not connected with this. The dependence of the sucess of re-crystallisation on the re-forming parameters (re-forming temperature and degree of re-forming) was shown by a socalled re-forming card. In order to achieve re-crystallisation to a coarse and aligned grain structure, apart from a certain absolute minimum degree of re-forming, the re-forming must occur within a defined ...
Objective: To evaluate the treatment of malignant biliary stenoses and occlusions using a new stent. Methods: In a prospective study, 25 patients with malignant obstructive jaundice were treated with SMART stents. The handling and the quality of stent expansion were documented. Stent function was assessed 2-4 days after intervention by cholangiography and laboratory tests. A follow-up was performed three months, after stent placement. Results: All lesions were treated successfully, with a total of 35 stents implanted. In 14 patients a further balloon dilatation was performed after stent placement (8-10 mm diameter/40-80 mm length). The mean serum bilirubin level decreased significantly from 11.6 mg/dl to 4.6 mg/dl after intervention (p<0.05). The follow-up showed a mean serum bilirubin level at 4.0 mg/dl. In 4 cases (16%) a further intervention (PTCD or stent) was performed. Six patients died due to tumor progression. The stents proved to be patent in 79% (n=15) of patients ...
Purpose: To report on the nephron-sparing, percutaneous ablation of a large renal cell carcinoma by combined superselective embolization and percutaneous radiofrequency ablation. Materials and Methods: A 5 cm renal cell carcinoma of a 43-year-old drug abusing male with serologically proven HIV, hepatitis B and C infection, who refused surgery, was superselectively embolized using microspheres (size: 500 - 700 {mu}m) and a platinum coil under local anesthesia. Percutaneous radiofrequency ablation using a 7F LeVeen probe (size of expanded probe tip: 40 mm) and a 200 Watt generator was performed one day after transcatheter embolization under general anesthesia. Results: The combined treatment resulted in complete destruction of the tumor without relevant damage of the surrounding healthy renal tissue. The patient was discharged 24 hours after RF ablation. No complications like urinary leaks or fistulas were observed and follow up CT one day and 4 weeks after the radiofrequency ...
Purpose: To evaluate a T{sub 2}-weighted URSE sequence for the assessment of pulmonary infiltrations in comparison to CT. Methods: 28 MRT scans of 22 patients with confirmed pneumonia were recorded on a 1.5 Tesla apparatus with an expiratory and diastolic triggered, T{sub 2}-weighted ultrafast-spin-echo sequence in axial slice mode with the following parameters: TR{sub eff}/T{sub E}/Turbofactor 2000-4000/90 ms/21-23; slice thickness/separation 6/0.6 mm; FOV 360 mm; 24 slices. 24 spiral CTs (sice thickness/table advance: 1-2 mm/10 mm) were available for comparison. The separate evaluation of MRTs and CTs was performed by three radiologists in a consensus procedure with regard to pulmonary lesions (e.g., infiltration, round foci, net patterns) and image quality of the MRTs (4-step scale). Results: In 71% of the cases the CTs and MRTs agreed with the diagnosis and representation of the lesions, in 25% MRT was superior. MRT was better for the detection of pulmonary abscesses. In 93% the ...
Purpose: Liposarcoma is the most common soft tissue sarcoma in adults. The purpose of the study was to correlate MR imaging features with the four ICD subclasses. Methods: 28 patients with liposarcoma were examined preoperatively on a 1.0 T MRI system, using spin echo sequences, gradient echo imaging and STIR sequences. In all patients, classification of the liposarcomas was made by histologic diagnosis (ICD-10-M-classification). Results: Well differentiated liposarcomas (9 patients) showed a number of MRI features consistent with lipoma (well defined mass high signal intensity (SI) on T{sub 1} images, low signal on T{sub 2} images, no or only little signal increase of tumour tissue after contrast material application, no necrosis). Not well differentiated liposarcomas (myxoid 14 patients, pleomorphic three patients, round cell two patients) revealed the largest part of the mass to be of low SI on T{sub 1}-weighted images. Only scattered fatty islands and septa (9 patients with myxoid ...
Purpose: To determine the value of MRI in the preoperative evaluation of chronic paranasal sinusitis and to compare the results with CT and intraoperative findings. Method/Materials: 42 patients with clinical signs of chronic paranasal sinusitis underwent MRI after CT evaluation on one day, with subsequent functional endoscopic sinus surgery on the next day. Coronary CT was obtained with 5-mm slices and table-feed in the prone position, while MRI was performed in the supine position with coronary T{sub 2}-TSE+pd and coronary and transverse HASTE, each with 5-mm slice thickness. Aquisition time in MRI was less than 8 minutes. Two radiologists reviewed the CT and MRI scans for signs of sinusitis and detection of anatomical landmarks. The results were correlated with the intraoperative findings. Results: MRI offered no artifacts of dental work and showed more often high quality pictures than CT. CT and MRI demonstrated a good correlation in the detection of mucosal pathologies ...
Purpose: To determine the diagnostic value of high resolution MR imaging with a circularly polarised (c.p.) body phased-array coil for the staging of pelvic lymph nodes in cervical carcinoma. Material and methods: 42 patients with histologically proven carcinoma of the cervix were studied on a 1.5 T scanner by using a c.p. body phased-array coil. The imaging protocol included T{sub 2}-weighted turbo-spin-echo (TSE) and T{sub 1}-weighted spin-echo sequences pre and post IV application of Gd-DTPA; slice thickness was 5-7 mm and pixel size 0.53 mm{sup 2}. Lymph nodes with a diameter of {>=}8 mm were considered to have metastatic involvement. MR imaging results were compared with histopathologic findings. Results: MR imaging showed enlarged lymph nodes ({>=} 8 mm) in 16 of 18 patients with histologic proof of lymph node metastases (sensitivity 89%). In 22 of 24 cases MR findings were true negative (specificity 92%). Diagnostic accuracy was 91%. Conclusion: High-resolution MR imaging ...
Nuclear energy will have to cope more and more with a rapid changing environment due to economic competitive pressure and the deregulatory progress. In current economic environment, utilities will have to focus strongly on the reduction of their total generation costs, covering the fuel cycle costs, which are only partly under their control. Developments in the fuel cycle will be in the short-term rather evolutionary addressing the current needs of utilities. However, within the context of sustainable development and more and more inclusion of externalities in energy generation costs, more performing developments in the fuel cycle could become important and feasible. A life-cycle design approach of the fuel cycle will be requested in order to cover all factors in order to decrease significantly the nuclear energy generation cost to complete with other alternative fuels in the long-term. This paper will report on some of the trends one could distinguish in the fuel cycle with emphasis ...
Functional imaging of the pharynx used to be the domain of cineradiography, CT and ultrafast CT. The development of modern MRI techniques led to new access to functional disorders of the pharynx. The aim of this study was to implement a new MRI technique to examine oropharyngeal obstructive mechanisms in patients with obstructive sleep apnea (OSA). Sixteen patients suffering from OSA and 6 healthy volunteers were examined on a 1.5 T whole-body imager (`Vision`, Siemens, Erlangen Medical Engineering, Germany) using a circular polarized head coil. Imaging was performed with 2D flash sequences in midsagittal and axial planes. Patients and volunteers were asked to breathe normally through the nose and to simulate snoring and the Mueller maneuver during magnetic resonance imaging (MRI). Prior to MRI, all patients underwent an ear, nose and throat (ENT) examination, functional fiberoptic nasopharyngoscopy and polysomnography. A temporal resolution of 6 images/s and an in-plane resolution of ...
This assessment is a feasibility study according to ISO 14024. It deals with the question whether an ecolabel is suitable for wood pellet heating systems and how concrete criteria for an ecolabel for wood pellet heating plants could be specified. The study begins with a comprehensive market analysis in order to identify possible plants for which an ecolabel would make sense. In the main part of the study, the environmental relevance of the chosen plants is analysed. For this analysis, plant manufacturers were interviewed and a comparison between wood pellet heating systems and heating systems which use gas, oil or wood was carried out. On the basis of this analysis, it was possible to derive a number of criteria which were discussed with company representatives and other experts in this field. As a result of this dialogue and the investigation process as a whole, the introduction of an ecolabel for wood pellet heating plants can be recommended. Wood pellet heating systems are ...
Under the repository storage conditions of Eram and Konrad, waste packages designed for permanent storage must not contain or release freely mobile liquids, except for the minimum residues attainable by reasonable efforts or unavoidable. In accordance with a directive issued by the German Federal Ministry for the Environment (BMU), waste conditioning must be carried out so as to minimize waste volumes and, if possible, on the site where the waste arises. Liquid waste is conditioned most effectively by drying. At the present time, various different processes for drying liquid waste are employed as reflected by the state of the art: The Robe process; roller drying; the RDA process; Favorit; in-drum drying; and HPA liquid waste drying with make-up feed. The HPA process offers these advantages: Drying under atmospheric conditions, which means high level of dryness (freely mobile and releasable water is removed); the residual water content is 10%; isothermal drying by hot air, which ...
Present day mammography has not been able to make use of the advantages of digital luminescence radiography because of the limited spatial resolution. The recent development of electromagnetic focusing X-ray tube with effective focal spot sizes from 0.04 to 0.12 mm allows radiographic direct magnification with less geometric blur. It is now possible to combine direct magnification mammography with digital luminescence radiography. By combining high quality storage phosphor screens with an HQ-workstation a spatial resolution of 8 lp/mm is possible for 1.7-fold magnification. For 4-fold spot magnification views spatial resolution can be theoretically increased to approx. 20 lp/mm. One important advantage of digital radiography is the possibility of image-postprocessing. This article presents two sets of standard parameters and three sets of image dependent parameters for better imaging of specific lesions, such as microcalcifications. The introduction of the storage phosphor screen ...
A cooperative effort of the Center for Solar Energy and Hydrogen Research (ZSW) and Phototronics Solartechnik GmbH (PST) aimed at the transfer of highly efficient solar cells developed on a laboratory scale, to large-area thin-film solar modules suitable for production. This work was based on research and development at the Institute for Physical Electronics (IPE) of Stuttgart University and ZSW on one hand, and on the know-how of PST in regard to large-area module fabrication on the other hand. The various thin-film layers of the cells and modules comprize molybdenum as rear contact, copper-indium(gallium)-diselenide (CIGS) as absorber material, the combination of cadmium sulphide (CdS) and ZnO as window layer. To produce these layers on large areas (30x30 cm{sup 2}), equipment was constructed and procedures were developed. Monolithic series connection of cells, used in other thin-film technologies, was studied and optimized by suitable patterning procedures, such as laser-scribing, ...
Against the background of more severe limitation of particle emission in all application areas of Diesel engines, it is necessary to monitor the particle emission, but also the chemical composition of the particles. The basis of assessing particle emission is formed by gravimetric determination of the particle concentration from exhaust gas diluted with particle-free ambient air, with a maximum temperature of 52 degrees C at the sampling position. While it is already possible, using the part flow dilution system, to take samples locally, previously the subsequent particle determination and characterisation could only be done in a chemical laboratory. For this reason, the C/S particle measurement process was developed as an alternative to gravimetry, which can be used locally, eg: on ships and which makes it possible to determine the particle mass and composition. This process is based on a thermographic carbon and sulphate determination. Comparative investigations were done both on ...
The quantitative measurement of carbon concentration-distance curves serves as fundamental prerequisite for the evaluation of rim zone properties connected with decarburisation processes in material science. This was shown in part 1 of the present work with two samples from through-hardenable rolling bearing steel 100Cr6 (SAE 52100) austenitised in different oxidising atmospheres by position dependent determination of hardness, residual stresses, and X-ray line broadening ({l_brace}211{r_brace} {alpha}'-Fe diffraction line). In practice, it is important to predict carbon concentration-distance curves under prevailing heat treatment conditions or to conclude conversely from profile measurements. Based on a refined kinetics model of a diffusion-controlled process, part 2 therefore presents a simulation tool developed by means of the finite element method (FEM). Apart from the concentration dependence of the diffusion coefficient, it also considers the decarburisation induced ...
Methods: Systemic irradiation of neuroaxis is an essential part in the management of medulloblastoma, stPNET and intracranial germ cell tumors. The introduction of quality assurance programs in radiooncology assures a precise radiotherapy of target volumes and is a prerequisite to improve survival. Results: Hyperfractionated radiotherapy has the potential of increasing dose to tumor more safely without increasing the risk for late adverse effects. Pilot studies revealed excellent tumor control in medulloblastoma with acceptable acute toxicity and a long-term survival of up to 96%. In medulloblastoma stereotactic radiation techniques reveal an acceptable toxicity and promising results in tumor control in recurrent disease or as primary treatment. They are now part of future treatment protocols in case of persisting residual tumor. Radiotherapy alone in pure germinoma is continuously yielding high cure rates. In secreting germ cell tumors cisplatin containing chemotherapies in ...
In areas where radiation dose monitoring has not been performed, it is essential to use material available in the environment be able to rapidly assess doses to individuals for immediate emergency medical care or for general estimation of the radiological consequences. It was shown that certain types of telephone cards containing microchips have the potential to be used as individual radiation dosimeters in emergency situations to detect doses over 250 mGy by luminescence measurements. In order to understand the dosimetric properties of chip cards, the components obtained from INFINIEON Company at various stages of production were used for luminescence measurements. It is found that the protecting layer used above the chips so called 'globe top' is the main source of radiation induced signal in chip cards. The globe top produced by INFINIEON at that stage is found to contain SiO2 and Epoxy. In order to improve the dosimetric properties of the chip cards, the raw material of the globe ...
Full text: Radiotherapy treatment planning (RTP) relies heavily on medical imaging. Until recently, the most important planning tool was the treatment simulator. The kilovoltage radiographic capabilities in a treatment simulator enabled the boundaries of treatment fields to be visualized with respect to bony anatomic landmarks. Perhaps the most important advance in treatment planning in recent years is the ability to visualize the passage of the beams with respect to a more accurate geometrical representation of the tumor and other soft tissue structures. This 'virtual simulation' uses a computer-based representation of a patient to determine the extent of the disease and the location of radiation sensitive normal tissue. Computer tomographic (CT) imaging produces a high-resolution three-dimensional representation of anatomy that can be correlated with other image sets such as magnetic resonance images (MRI) of function. Positron emission tomographic (PET) imaging is beginning to be ...
In an epidemiological study of the somatic late effects risk following incorporation of a short lived {alpha}-emitter, 1473 ankylosing spondylitis patients treated with repeated intravenous injections of {sup 224}Ra in the years 1948 - 75, have been observed in the GSF. The usual therapeutic plan consisted of a total of 10 - 12 injections of 1.036 MBq (28 {mu}Ci) of {sup 224}Ra each, given at weekly intervals; this would result in an cumulative {alpha}-dose of 0.56 - 0.67 Gy to the marrow-free skeleton of a 70-kg-man (standard man). These patients have been followed together with a control group of ankylosing spondylitis patients not treated with radioactive drugs and/or X-rays. Until May 1993 (mean follow-up time 19.9 yr), 595 patients of the exposure group and 722 patients of the control group have died, causes of death have been ascertained for 578, resp. 668 patients. Among others we observed in the exposure group 10 cases of leukaemia (vs. 2.7 - 2.8 cases expected, p < 0.001) ...
Purpose: {sup 31}P-MRS is used to assess the influence of sex and age on quadriceps muscle metabolism before and after exercise. Materials and Methods: 32 healthy volunteers (15 women, 17 men; mean age: 38{+-}17 yrs.) were examined by dynamic phosphorus-31 ({sup 31}P) magnetic resonance spectroscopy (MRS). In the magnet, the quadriceps muscle was stressed by an isometric and an isotonic form of exercise until exhaustion, respectively. Results: Resting conditions: With increasing subjects` age, the ratio {beta}-adenosine triphosphate/total phosphate decreased (r=-0.37; p=0.02). With increasing subjects` age, the ratios inorganic phosphate/phosphocreatine (r=0.79; p=5x10{sup -8}), phosphomonoester/{beta}-adenosine triphosphate (r=0.74; p=10{sup -6}) and phosphodiester/{beta}-adenosine triphosphate (r=0.62; p=10{sup -4}) increased. The pH was the only one of the evaluated spectroscopic parameters which showed a sex-dependence: Female subjects had a significantly lower pH (7.03{+-}0.02) ...
Pr{sub 2}[Mo{sub 2}C{sub 3}] was obtained by arc melting of the elements followed by annealing at 1500 C in arc welded and sealed Mo-ampoules. The compound was characterised by chemical analyses, X-ray diffraction and metallography. The crystal structure (monoclinic, P2{sub 1}/c, Z = 4, a = 597.99(10) pm, b = 665.15(11) pm, c = 1185.60(19) pm and {beta} = 111.631(5) ) represents a new structure type containing a three dimensional polyanion {sub {infinity}}{sup 3}[(Mo{sub 2}C{sub 3}){sup 6-}] with Molybdenum(III) in a distorted tetrahedral coordination by carbo-ligands. Tetrameric building-blocks, Mo{sub 4}C{sub 10}, of edge sharing MoC{sub 4}-tetrahedra are arranged to form layers running parallel to (100). The layers are interconnected along [100] by sharing common apices of the MoC{sub 4} tetrahedra. The coordination polyhedra around praseodymium represent distorted (PrC{sub 5})-arrangements (mono capped tetrahedra and square pyramids). The metal atoms together form a distorted motif ...
Low energy buildings promise significant energy savings and help climate preservation by cutting down on annual heating requirements to values below 70 kWh per m{sup 2} dwelling space. It is expected that low energy constructions will become the common standard by the year 2000 as a result of the forthcoming energy saving ordinance. For making the introduction and implementation of this standard successful, practical experience will be essential. For this reason, the state government of Hesse has supported respective pilot projects 1987. In 1989 the funding programme `30 low energy buildings in Hesse` has been established. Consecutively - between 1989 and 1993 - 29 buildings were erected. At first, the thermal quality of the crafted building construction including the ventilation systems was checked. Consecutively, energy consumption, indoor and outdoor temperatures were measured over a time span of several years. The experience of the inhabitants was surveyed. The `Institut Wohnen und ...