WorldWideScience
2

CDC - Seasonal Influenza (Flu) - Q & A: 2007-08 Influenza (Flu...  

Science.gov (United States)

home when you are sick helps everyone you care about Questions & Answers Flu Vaccine: Q&A Vaccine Dosage & Administration Vaccine Supply for 2011-12 Season Vaccine Supply and...

2011-10-15

3

CDC - Seasonal Influenza (Flu) - Q & A: 2006-07 Influenza (Flu...  

Science.gov (United States)

home when you are sick helps everyone you care about Questions & Answers Flu Vaccine: Q&A Vaccine Dosage & Administration Vaccine Supply for 2011-12 Season Vaccine Supply and...

2011-10-15

4

CDC - Seasonal Influenza (Flu) - Q & A about the 2010-2011 Flu...  

Science.gov (United States)

home when you are sick helps everyone you care about Questions & Answers Flu Vaccine: Q&A Vaccine Dosage & Administration Vaccine Supply for 2011-12 Season Vaccine Supply and...

2011-10-15

5

Influenza Vaccines  

International Science & Technology Center (ISTC)

Development of the Culture Influenza Vaccine

6

CDC - Seasonal Influenza (Flu) - Questions and Answers - Guillain...  

Science.gov (United States)

Effectiveness Flu Shot Nasal Spray Vaccine (LAIV) Thimerosal Guillain-Barré Syndrome (GBS) Antiviral Drugs: Key Facts Antiviral Drugs: Q&A Antiviral Drug Resistance Links,...

2011-09-24

7

Serological testing-An alternative to boosters?  

British Library Electronic Table of Contents (United Kingdom)

The issue of the duration of immunity, particularly for the modified live viral components of veterinary vaccines, has been a significant part of the recent vaccination debate. One manufacturer has increased the recommended booster interval for these components to 3 years give name and another now states `up to 4 years' immunity.There remain many unanswered questions regarding this duration of immunity (DOI). Studies suitable for data sheet claims are time consuming and costly and can only be performed in laboratory dogs under tightly controlled conditions. Evidence from rabies serology testing in the UK shows that the response of individual animals to routine vaccination is highly variable. Much of the published field evidence on the persistence of antibody titres originates from North Am...

2006-01-01

8

Possible association of lower rate of postherpetic neuralgia in patients on anti-tumor necrosis factor-  

British Library Electronic Table of Contents (United Kingdom)

Abstract Recently, a study of patients with rheumatoid arthritis who developed herpes zoster while taking a tumor necrosis factor (TNF)- inhibitor reported a decreased incidence of postherpetic neuralgia. The objective of this study was to investigate whether patients on TNF- inhibitors who developed herpes zoster have a lower incidence of subsequent development of postherpetic neuralgia. A retrospective review of herpes zoster patients on TNF- inhibitors (infliximab, etanercept, or adalimumab) was conducted in 12 dermatology clinics. Medical records of such patients were reviewed thoroughly to confirm herpes zoster and TNF- inhibitors and any subsequent development of postherpetic neuralgia (pain score -3 out of 10 after 90 days of shingles onset) was noted. A total of 206 cases were revi...

2011-01-01

10

Influenza  

Medline Plus

... a flu shot There is a new nasal spray version of the vaccine, and it contains weakened ... the LAIV (Live Attenuated Influenza Vaccine). The nasal-spray flu vaccine contains three different live but weakened ...

12

Response to measles-mumps-rubella vaccine in children on dialysis.  

Science.gov (United States)

Ten children receiving maintenance dialysis were immunized with the standard dose of measles-mumps-rubella vaccine between 15 and 33 months of age. Immune responses to vaccination were determined using commercially available enzyme-linked immunosorbent assays for measles, mumps, and rubella viruses. Eight children responded to measles vaccine, 5 to mumps vaccine, 8 to rubella vaccine, and only 3 children to all three vaccines, compared with a seroconversion rate of over 90% to all three vaccines in healthy children (P less than 0.0001). We contend that the relatively poor immunocompetence of our dialysis patients explains their less than optimal vaccine response and suggest that children vaccinated while undergoing dialysis be tested to confirm serological evidence of immunity. PMID:1571219

1992-03-01

13

Follow-up of pregnant women exposed to chicken pox: an audit of relationship between level of antibody and development of chicken pox  

British Library Electronic Table of Contents (United Kingdom)

The purpose of this study was to validate through natural exposure a cut-off level of varicella zoster IgG as protective against infection with varicella zoster virus (VZV). Laboratory testing to determine VZV immune status of pregnant women exposed to varicella is recommended. Quantitative assays are now available which are sensitive and specific. More than 200 consecutive requests for screening in pregnant patients with recent varicella contacts were followed-up by questionnaire. DiaSorin LIAISON and VZV time resolved fluorescence immuno assay (VZV TRFIA) were used to measure VZV antibody level. One hundred fifty out of 209 (72%) questionnaires were returned; 14 patients developed varicella, 129 did not and seven were not known. Patients who had been given VZIG and developed varicella on...

2011-01-01

14

Advances in molecular biology: impact on rotavirus vaccine development.  

Science.gov (United States)

The first candidate rotavirus vaccine was a live attenuated oral vaccine made by the classical empirical method of serial passage of virus in tissue culture cells. Current tetravalent vaccine candidates that are in the final stages of efficacy testing in the United States were made by genetic reassortment. This article briefly highlights how advances in the basic understanding of the molecular biology of rotaviruses have facilitated vaccine development. New approaches for second-generation vaccines and improvements in vaccine efficacy based on further exploitation of the tools and knowledge of rotavirus molecular biology and pathogenesis are discussed. PMID:8752289

1996-09-01

15

Effect of duration of postherpetic neuralgia on efficacy analyses in a multicenter, randomized, controlled study of NGX-4010, an 8% capsaicin patch evaluated for the treatment of postherpetic neuralgia  

UK PubMed Central (United Kingdom)

BackgroundPostherpetic neuralgia (PHN) is a painful and difficult to treat complication of acute herpes zoster. Current treatment options provide only partial relief and are often...Full Text Available

16

Safety and immunogenicity of a vaccine bait containing ERA strain of attenuated rabies virus.  

UK PubMed Central (United Kingdom)

Ninety percent of foxes fed commercial ERA vaccine in a specially designed bait developed rabies serum neutralizing antibodies. The vaccine bait did not cause clinical signs of rabies when consumed...Full Text Available

1987-10-01

17

Population-based prevention of influenza in Dutch general practice.  

UK PubMed Central (United Kingdom)

BACKGROUND: Although the effectiveness of influenza vaccination in high-risk groups has been proven, vaccine coverage continues to be less than 50% in The Netherlands. To improve vaccination rates,...Full Text Available

1997-06-01

18

Novel Approach for Differential Diagnosis of HIV Infections in the Face of Vaccine-Generated Antibodies  

UK PubMed Central (United Kingdom)

SummaryBecause increasing numbers of HIV vaccine candidates are being tested globally, it is essential to differentiate vaccine-from virus-induced antibodies. Most of the currently...Full Text Available

2006-11-01

19

Contrasting Population Structures of the Genes Encoding Ten Leading Vaccine-Candidate Antigens of the Human Malaria Parasite, Plasmodium falciparum  

UK PubMed Central (United Kingdom)

The extensive diversity of Plasmodium falciparum antigens is a major obstacle to a broadly effective malaria vaccine but population genetics has rarely been used to guide vaccine design....Full Text Available

20

A semi-qualitative study of attitudes to vaccinating adolescents against human papillomavirus without parental consent  

UK PubMed Central (United Kingdom)

BackgroundThe first vaccine to prevent human papillomavirus (HPV) and cervical cancer has been licensed, and in future, vaccination may be routinely offered to 10–14 year...Full Text Available

21

Isolation and Identification of Mycoplasmas  

International Science & Technology Center (ISTC)

Isolation and Identification of Mycoplasmas, Development of Reliable Antigen for Mycoplasmas Detection and Oil-Based Vaccines

22

The influence of MHC polymorphism on the selection of T-cell determinants of FMDV in cattle.  

UK PubMed Central (United Kingdom)

There is a quest for the development of a new generation of vaccines consisting of well-defined subunit antigens. For a number of practical reasons it is attractive to develop vaccines on the basis...Full Text Available

1995-01-01

23

Tat-Neutralizing Antibodies in Vaccinated Macaques  

UK PubMed Central (United Kingdom)

The human immunodeficiency virus Tat protein is essential for virus replication and is a candidate vaccine antigen. Macaques immunized with Tat or chemically modified Tat toxoid having the same clade...Full Text Available

2003-03-01

24

Synchronous infection of SIV and HIV in vitro for virology, immunology, and vaccine-related studies  

UK PubMed Central (United Kingdom)

The development of an HIV vaccine will require a more precise understanding of the immunological and virological underpinnings of HIV infection. Magnetofection, the process of magnetizing HIV...Full Text Available

2010-01-01

25

Safety and Immunogenicity of Novel Recombinant BCG and Modified Vaccinia Virus Ankara Vaccines in Neonate Rhesus Macaques ?  

UK PubMed Central (United Kingdom)

Although major inroads into making antiretroviral therapy available in resource-poor countries have been made, there is an urgent need for an effective vaccine administered shortly after birth, which...Full Text Available

2010-08-01

26

Pathway to Licensure for Protective Antigen-based Anthrax Vaccines ...  

Science.gov (United States)

... Weiss, S., D. Kobiler, H. Levy, H. Marcus, A. Pass, N. Rothschild, and Z ... of Bacillus anthracis spores conferred by a protective antigen-based vaccine in rabbits ...

27

Mothers' concept of measles and attitudes towards the measles vaccine in Ile-Ife, Nigeria.  

UK PubMed Central (United Kingdom)

The attitude of Nigerian mothers, mainly Yoruba, towards measles vaccine and other aspects of prevention are influenced by different perceptions of the cause of measles. There is a significant correlation...Full Text Available

1982-09-01

28

Molecular characterization of a Chinese variant of the Flury-LEP strain  

UK PubMed Central (United Kingdom)

The entire genome of rabies virus vaccine strain Flury-LEP-C, a Chinese variant of the rabies virus vaccine strain Flury-LEP, was sequenced. The overall length of the genome of Flury-LEP-C strain was...Full Text Available

29

Indian vaccine innovation: the case of Shantha Biotechnics  

UK PubMed Central (United Kingdom)

BackgroundAlthough the World Health Organization had recommended that every child be vaccinated for Hepatitis B by the early 1980s, large multinational pharmaceutical companies held...Full Text Available

30

Cryoglobinaemia in rabbits hyperimmunized with a polyvalent pneumococcal vaccine  

UK PubMed Central (United Kingdom)

During the anamnestic response, the sera of four rabbits immunized with a polyvalent pneumococcal vaccine contained large amounts of cryoglobulins belonging to the G and M immunoglobulin classes. These...Full Text Available

1965-10-01

31

Correlates to Increased Lethality of Attenuated Venezuelan Encephalitis Virus Vaccine for Immunosuppressed Hamsters.  

Science.gov (United States)

Splenectomy or pretreatment of adult hamsters with cyclophosphamide (Cytoxan) increased the lethality of the TC-83 vaccine strain of Venezuelan encephalitis virus (VEE), inoculated subcutaneously, from 12% for normal hamsters to 75 and 76% respectively. A...

1974-01-01

32

A viral vaccine encoding PSA induces antigen spreading to a common set of self proteins in prostate cancer patients  

UK PubMed Central (United Kingdom)

PurposeWe previously reported a randomized phase II clinical trial combining a poxvirus-based vaccine encoding PSA with radiotherapy in patients with localized prostate...Full Text Available

2010-08-01

33

Vaccination response to tetanus toxoid and 23-valent pneumococcal vaccines following administration of a single dose of abatacept: a randomized, open-label, parallel group study in healthy subjects  

UK PubMed Central (United Kingdom)

The effect of abatacept, a selective T-cell co-stimulation modulator, on vaccination has not been previously investigated. In this open-label, single-dose, randomized, parallel-group, controlled study,...Full Text Available

2007-01-01

34

Long-Term Specific Immune Responses Induced in Humans by a Human Immunodeficiency Virus Type 1 Lipopeptide Vaccine: Characterization of CD8+-T-Cell Epitopes Recognized  

UK PubMed Central (United Kingdom)

We studied the effect of booster injections and the long-term immune response after injections of an anti-human immunodeficiency virus type 1 (HIV-1) lipopeptide vaccine. This vaccine was injected alone...Full Text Available

2003-10-01

35

Comparison of a multivalent viral vaccine program versus a univalent viral vaccine program on animal health, feedlot performance, and carcass characteristics of feedlot calves  

UK PubMed Central (United Kingdom)

A field study was conducted under commercial feedlot conditions at 2 sites in western Canada to determine the relative effects of a univalent viral vaccine (MLV 1) program versus a multivalent viral...Full Text Available

2003-01-01

36

The immunological era in melanoma treatment: new challenges for heat shock protein-based vaccine in the advanced disease  

British Library Electronic Table of Contents (United Kingdom)

Introduction: Tumor-derived heat shock protein (HSP)-peptide complexes (HSPPCs) induced immunity against malignancies in preclinical trials, working across tumor types and bypassing the need to identify single immunogenic peptides. These results paved the way for the use of human gp96 obtained from autologous tumor samples as an anti-cancer vaccine. Areas covered: Autologous tumor-derived HSP gp96 peptide complex (HSPPC-96) vaccine is emerging as a tumor- and patient-specific cancer vaccine, with confirmed activity in several malignancies. It has been tested in Phase III clinical trials in advanced melanoma and kidney cancer with evidence for efficacy in patients with earlier stage disease. HSPPC-96-based vaccine demonstrated an excellent safety profile, thus emerging as a novel therapeuti...

2011-01-01

37

Current status of a hepatitis C vaccine: encouraging results but significant challenges ahead  

DEFF Research Database (Denmark)

Persistent hepatitis C virus (HCV) infection affects 170 million people worldwide. Acute HCV infection is often asymptomatic, but many infected individuals develop persistent infections that may lead to development of end-stage liver diseases, including liver cirrhosis and hepatocellular carcinoma. Thus, an HCV vaccine that could significantly lower the chronicity rate would have a major impact on the disease burden. Unfortunately, HCV is a highly mutable virus, and escape mutations can undermine vaccine-induced virus-specific immunity. Also, HCV exists as multiple genotypes, and so genotype-specific vaccines might be required to achieve broad protection. Finally, vaccine development has been hampered by the lack of a small animal model and cell culture systems, but these are currently being established. Despite these obstacles, several vaccine candidates tested in the chimpanzee ...

2007-01-01

38

The Case for Reactive Mass Oral Cholera Vaccinations  

UK PubMed Central (United Kingdom)

IntroductionThe outbreak of cholera in Zimbabwe intensified interest in the control and prevention of cholera. While there is agreement that safe water, sanitation, and personal...Full Text Available

39

Reversing B cell aging  

UK PubMed Central (United Kingdom)

Age-related alterations in the cellular composition of the B lineage are a major cause of the poor antibody response to vaccination and to infectious agents among the elderly population. The mechanisms...Full Text Available

40

Reporting Problems to FDA  

Medline Plus

Enter Search terms A-Z Index Home Food Drugs Medical Devices Vaccines, Blood & Biologics Animal & Veterinary Cosmetics Radiation-Emitting Products Tobacco ...

41

Health Information for Travelers to South Africa - Travelers...  

Science.gov (United States)

more information about this message, please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) South Africa Regions Vaccinations News & Announcements Travel...

2011-08-28

42

Health Information for Travelers to Somalia - Travelers' Health...  

Science.gov (United States)

more information about this message, please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) Somalia Regions Vaccinations News & Announcements Travel...

2011-08-28

43

Health Information for Travelers to Saudi Arabia - Travelers...  

Science.gov (United States)

more information about this message, please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) Saudi Arabia Regions Vaccinations News & Announcements Travel...

2011-08-28

44

Health Information for Travelers to Rwanda - Travelers' Health...  

Science.gov (United States)

more information about this message, please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) Rwanda Regions Vaccinations News & Announcements Travel...

2011-08-28

45

Health Information for Travelers to Mozambique - Travelers' Health...  

Science.gov (United States)

more information about this message, please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) Mozambique Regions Vaccinations News & Announcements Travel...

2011-08-28

46

Health Information for Travelers to Malawi - Travelers' Health...  

Science.gov (United States)

more information about this message, please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) Malawi Regions Vaccinations News & Announcements Travel...

2011-08-28

47

Health Information for Travelers to Kenya - Travelers' Health...  

Science.gov (United States)

more information about this message, please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) Kenya Regions Vaccinations News & Announcements Travel Notices...

2011-08-28

48

Health Information for Travelers to Iran - Travelers' Health...  

Science.gov (United States)

please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) Iran Regions Vaccinations News & Announcements Travel Notices Diseases Yellow Book Contents...

2011-09-04

49

Health Information for Travelers to Gabon - Travelers' Health...  

Science.gov (United States)

more information about this message, please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) Gabon Regions Vaccinations News & Announcements Travel Notices...

2011-08-28

50

Health Information for Travelers to Ethiopia - Travelers' Health...  

Science.gov (United States)

more information about this message, please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) Ethiopia Regions Vaccinations News & Announcements Travel...

2011-08-28

51

Health Information for Travelers to Eritrea - Travelers' Health...  

Science.gov (United States)

more information about this message, please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) Eritrea Regions Vaccinations News & Announcements Travel...

2011-08-28

52

Health Information for Travelers to Equatorial Guinea - Travelers...  

Science.gov (United States)

more information about this message, please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) Equatorial Guinea Regions Vaccinations News & Announcements...

2011-08-28

53

Health Information for Travelers to Djibouti - Travelers' Health...  

Science.gov (United States)

more information about this message, please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) Djibouti Regions Vaccinations News & Announcements Travel...

2011-08-28

54

Health Information for Travelers to Democratic Republic of the...  

Science.gov (United States)

more information about this message, please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) Democratic Republic of the Congo Regions Vaccinations News &...

2011-08-28

55

Health Information for Travelers to Antarctica - Travelers' Health...  

Science.gov (United States)

more information about this message, please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) Antarctica Regions Vaccinations News & Announcements Travel...

2011-08-28

56

Diphtheria in Europe.  

UK PubMed Central (United Kingdom)

A letter of inquiry was sent to 21 countries in Europe to ascertain their experience of diphtheria during the last 20 years. An analysis of the 15 replies showed that all relied on childhood vaccination...Full Text Available

1984-12-01

57

Controlling Endemic Cholera with Oral Vaccines  

UK PubMed Central (United Kingdom)

BackgroundAlthough advances in rehydration therapy have made cholera a treatable disease with low case-fatality in settings with appropriate medical care, cholera continues...Full Text Available

2007-11-01

58

Bioterrorism and Biocrimes: The Illicit Use of Biological Agents ...  

Science.gov (United States)

... view on the utility of such attacks, see JH Rothschild, Tomorrow's Weapons ... Aum Shinrikyo may have had a stolen vaccine anthrax strain incapable ...

2001-02-01

59

A multifactorial strategy of pain management is associated with less pain in scheduled vaccination of children. A study realized by family practitioners in 239 children aged 4-12 years old  

British Library Electronic Table of Contents (United Kingdom)

Background and aims. The multiplicity of vaccine injections during childhood leads to iterative painful and stressful experiences which may lead in turn to anticipated pain and then possibly to a true needle phobia. We aimed at evaluating a multifactorial strategy of pain management combining pharmacological and non-pharmacological approaches during vaccination, as compared to usual care, in 4- to 12-year-old children. Methods. In all, 239 children were enroled by 25 family practitioners in an open-label study. After a pseudo-randomization, usual pain management (n = 132) was compared to a multifactorial strategy (n = 107) associating preliminary application of an anesthesic patch, preferential use of specified vaccines, child education by the parents and the doctor, parental accompaniment...

2008-01-01

60

A Novel Multi-Antigen Virally Vectored Vaccine against Mycobacterium avium Subspecies paratuberculosis  

UK PubMed Central (United Kingdom)

BackgroundMycobacterium avium subspecies paratuberculosis causes systemic infection and chronic intestinal inflammation in many species including...Full Text Available

61

T Cell Responses to the RTS,S/AS01E and RTS,S/AS02D Malaria Candidate Vaccines Administered According to Different Schedules to Ghanaian Children  

UK PubMed Central (United Kingdom)

BackgroundThe Plasmodium falciparum pre-erythrocytic stage candidate vaccine RTS,S is being developed for protection of young children against...Full Text Available

62

Preliminary Assessment of the Safety and Immunogenicity of a New CTX?-Negative, Hemagglutinin/Protease-Defective El Tor Strain as a Cholera Vaccine Candidate  

UK PubMed Central (United Kingdom)

Vibrio cholerae 638 (El Tor, Ogawa), a new CTXΦ-negative hemagglutinin/protease-defective strain that is a cholera vaccine candidate, was examined for safety and immunogenicity...Full Text Available

1999-02-01

63

Potent immune responses and in vitro pro-inflammatory cytokine suppression by a novel adenovirus vaccine vector based on rare human serotype 28  

UK PubMed Central (United Kingdom)

Adenovirus vaccine vectors derived from rare human serotypes have been shown to be less potent than serotype 5 (Ad5) at inducing immune responses to encoded antigens. To identify highly immunogenic...Full Text Available

2010-08-09

64

NAME=\\  

Wastenet

...INFORMATION Diarrhoeal disease Food safety and foodborne illness Enterohaemorrhagic Escherichia coli (EHEC) Cholera WHO PROGRAMMES AND ACTIVITIES Child and Adolescent Health and Development (...FOS) Initiative for Vaccine Research (IVR) TECHNICAL INFORMATION Vaccine research: diarrhoeal diseases Cholera Water-related diseases Household water treatment and safe storage WHO Global Salm-Surv ...PUBLICATIONS Diarrhoea: child and adolescent health Diarrhoea: cholera RELATED TOPICS - Child health - Water - Food safety - Cholera - Travel - Breastfeeding ...

65

Molecular Characterization of a Haemaphysalis longicornis Tick Salivary Gland-Associated 29-Kilodalton Protein and Its Effect as a Vaccine against Tick Infestation in Rabbits  

UK PubMed Central (United Kingdom)

The use of tick vaccines in mammalian hosts has been shown to be the most promising alternative tick control method to current use of acaricides, which suffers from a number of limitations. However,...Full Text Available

1999-04-01

66

Efficacy of a heat inactivated hepatitis B vaccine in male homosexuals: outcome of a placebo controlled double blind trial.  

UK PubMed Central (United Kingdom)

The efficacy of a heat inactivated hepatitis B virus vaccine, containing 3 micrograms hepatitis B surface antigen (HBsAg), was studied in a high risk group of 800 susceptible homosexual men by a randomised...Full Text Available

1983-04-23

67

Effects of 2 commercially-available 9-way killed vaccines on milk production and rectal temperature in Holstein-Friesian dairy cows.  

UK PubMed Central (United Kingdom)

Veterinarians and farmers employing multivalent killed vaccines in lactating dairy cows have reported transient losses in milk production. Few studies have quantified this loss. In this report, effects...Full Text Available

2001-10-01

68

A recombinant Yellow Fever 17D vaccine expressing Lassa virus glycoproteins  

UK PubMed Central (United Kingdom)

The Yellow Fever Vaccine 17D (YFV17D) has been used as a vector for the Lassa virus glycoprotein precursor (LASV-GPC) resulting in construction of YFV17D/LASV-GPC recombinant virus. The virus...Full Text Available

2006-02-20

69

A Randomized Trial Assessing the Safety and Immunogenicity of AS01 and AS02 Adjuvanted RTS,S Malaria Vaccine Candidates in Children in Gabon  

UK PubMed Central (United Kingdom)

BackgroundThe malaria vaccine candidate antigen RTS,S includes parts of the pre-erythrocytic stage circumsporozoite protein fused to the Hepatitis B surface antigen. Two Adjuvant...Full Text Available

70

2000-centiGray total lymphoid irradiation for refractory rheumatoid arthritis  

International Nuclear Information System (INIS)

Because toxicity with the use of 3000 centiGray (cGy) of total lymphoid irradiation (TLI) was observed in an earlier study, 2000-cGy treatments were delivered in a 2-portal format to 7 patients and in a modified 3-portal fashion to 6 patients, as part of a randomized, investigator-blinded trial of TLI treatment for refractory rheumatoid arthritis. Analysis of combined data from the 13 patients revealed statistically significant improvement in 5 clinical indicators of disease activity at the end of TLI and 6 and 12 months later, accompanied by T4-specific immunosuppression. Management considerations resulted in the introduction of prednisone therapy in 5 patients, methotrexate in 4, and azathioprine in 1 during the interval of 8-12 months post-TLI. Herpes zoster occurred in 5 patients prior to the initiation of this additional therapy. These data indicate that, in patients with rheumatoid arthritis, a TLI dose of 2000 cGy is sufficient to produce measurable benefit ...

71

Flue Gas Desulfurization: Answers to Basic Questions.  

Science.gov (United States)

The purpose of this publication is to provide a better understanding of flue gas desulfurization. It provides brief answers to questions concerning its applicability, cost, effectiveness, and operation.

1973-01-01

72

Drawing Feynman Diagrams with Latex and METAFONT, Part 3: Extension Mechanism and Frequently Asked Questions  

CERN Document Server

Drawing Feynman Diagrams with Latex and METAFONT, Part 3: Extension Mechanism and Frequently Asked Questions

1996-01-01

73

Immunogenicity, efficacy, safety and effectiveness of pneumococcal conjugate vaccines (1998-2006)  

British Library Electronic Table of Contents (United Kingdom)

In this paper we present an overview of the literature on efficacy and safety trials of the various pneumococcal conjugate vaccines on the market (PCV7) and in development (PCV9, PCV11 and allegedly PCV10 and PCV13), as well as of observations from post-licensure studies. Seven- (PCV7) and nine-valent PCV (PCV9) are reported to be sufficiently immunogenic after administration of a 3+1 schedule in infants in various RCTs. PncOMPC (PCV7 with a protein of N. meningitidis as a carrier) is less immunogenic, though this may have no repercussions for the protective efficacy against clinical disease. PCV7 is 82-97% efficacious against vaccine serotype (VT) IPD, 90% efficacious against (clinically diagnosed) pneumococcal pneumonia, and, like the 11-valent PCV, 57% efficacious against VT acute otiti...

2007-01-01

74

An oral nervous necrosis virus vaccine using Vibrio anguillarum as an expression host provides early protection  

British Library Electronic Table of Contents (United Kingdom)

Oral vaccination is the most desirable immunization method by which to prevent fish disease occurring at the early larval stage. We developed an Escherichia coli-based oral nervous necrosis virus (NNV) subunit vaccine and demonstrated its effectiveness in orange spotted grouper (Epinephelus coioides) fry. However, the incubation period was determined to be over 2weeks. To enhance the efficacy and shorten the incubation period, a safe and digestible biological adjuvant should be found. Vibrio anguillarum, a common marine bacterium with immune-stimulatory capability was selected as an expression host. An expression vector containing its heat shock protein 60 gene (groE) as an inducible promoter was constructed to express recombinant NNV coat protein as an antigen. The recombinant V. anguilla...

2011-01-01

75

Therapeutic Vaccination in Chronic Hepatitis B: Preclinical Studies in the Woodchuck  

UK PubMed Central (United Kingdom)

Recommended treatment of chronic hepatitis B with interferon-α and/or nucleos(t)ide analogues does not lead to a satisfactory result. Induction of HBV-specific T cells by therapeutic...Full Text Available

2010-01-01

76

The hemoglobins of the trematodes Fasciola hepatica and Paramphistomum epiclitum: A molecular biological, physico-chemical, kinetic, and vaccination study  

UK PubMed Central (United Kingdom)

The trematode Fasciola hepatica (Fa.he.) is a common parasite of human and livestock. The hemoglobin (Hb) of Fa.he., a potential immunogen, was chosen for characterization...Full Text Available

2008-10-01

77

Testing the Efficacy of a Multi-Component DNA-Prime/DNA-Boost Vaccine against Trypanosoma cruzi Infection in Dogs  

UK PubMed Central (United Kingdom)

BackgroundTrypanosoma cruzi, the etiologic agent of Chagas Disease, is a major vector borne health problem in Latin America and an emerging...Full Text Available

78

Taking social relationships seriously: Lessons learned from the informed consent practices of a vaccine trial on the Kenyan Coast  

UK PubMed Central (United Kingdom)

AbstractIndividual informed consent is a key ethical obligation for clinical studies, but empirical studies show that key requirements are often not met. Common recommendations to strengthen...Full Text Available

2008-09-01

79

Syndecan-Fc Hybrid Molecule as a Potent In Vitro Microbicidal Anti-HIV-1 Agent?  

UK PubMed Central (United Kingdom)

In the absence of a vaccine, there is an urgent need for the development of safe and effective topical microbicides to prevent the sexual transmission of human immunodeficiency virus type 1 (HIV-1)....Full Text Available

2010-07-01

80

Strategies for the production of genetically identical monkeys by embryo splitting  

UK PubMed Central (United Kingdom)

Genetically identical rhesus monkeys would have tremendous utility as models for the study of human disease and would be particularly valuable for vaccine trials and tissue transplantation studies where...Full Text Available

81

Serum Concentrations of Antibodies Against Vaccine Toxoids in Children Exposed Perinatally to Immunotoxicants  

UK PubMed Central (United Kingdom)

BackgroundPolychlorinated biphenyls (PCBs) may cause immunotoxic effects, but the detailed dose–response relationship and possible vulnerable time windows of exposure are...Full Text Available

2010-10-01

82

Rubella screening and vaccination program for US Air Force trainees: an analysis of findings.  

UK PubMed Central (United Kingdom)

A preventive medicine program of rubella control for trainees at the Air Force Military Training Center, Lackland AFB, Texas, was begun in October 1977. Incoming trainees were screened for rubella susceptibility,...Full Text Available

1982-03-01

83

Regulatory compliance | Mott MacDonald  

Wastenet

...broad range of experience in designing and building research and development laboratories for products such as vaccines, blood and sera, biological products, medical devices, solid dosage forms , highly potent products and cytotoxic material. We also have experience in a range of modular laboratories for TSE research, ...

84

Prevention of clinical coliform mastitis in dairy cows by a mutant Escherichia coli vaccine.  

UK PubMed Central (United Kingdom)

A prospective cohort study was undertaken in two commercial California dairies. The treatment group, 246 cows, received three doses of a whole cell bacterin of J5 Escherichia coli (mutant of E. coli...Full Text Available

1989-07-01

85

Polyantigenic Interferon-? Responses Are Associated with Protection from TB among HIV-Infected Adults with Childhood BCG Immunization  

UK PubMed Central (United Kingdom)

BackgroundSurrogate immunologic markers for natural and vaccine-mediated protection against tuberculosis (TB) have not been identified.MethodsHIV-infected...Full Text Available

86

Poliomyelitis control in Israel, the West Bank and Gaza Strip: changing strategies with the goal of eradication in an endemic area.  

UK PubMed Central (United Kingdom)

Israel has faced the challenge presented by epidemic poliomyelitis by using different immunization strategies. In the 1950s, inactivated poliovirus vaccine (IPV) helped to reduce the total burden of...Full Text Available

1994-01-01

87

Plasminogen-125I responses in dogs to a single injection of urokinase and typhoid vaccine and to vascular injury  

UK PubMed Central (United Kingdom)

In vivo plasminogen responses to various stimuli were studied. Plasminogen-125I was prepared and used first for metabolic studies of plasminogen in control dogs. The average results were:...Full Text Available

1972-06-01

88

Peru-15, an improved live attenuated oral vaccine candidate for Vibrio cholerae O1.  

Science.gov (United States)

Cholera vaccine candidate Peru-15 was derived from a Vibrio cholerae O1 El Tor Inaba strain by deleting the cholera toxin genetic element, introducing the gene encoding cholera toxin B subunit into recA, and screening for nonmotility. In a controlled study, Peru-15 (2 x 10(8) cfu) was administered to 11 volunteers. No vaccinee developed diarrhea, and 10 of 11 had > 4-fold rises in vibriocidal antibody titers. One month later, 5 vaccinees and 5 control volunteers were challenged with wild type V. cholerae O1. Four of 5 controls developed diarrhea (mean, 1.9 L). Two Peru-15 vaccinees developed diarrhea, 1 with < 0.3 L and 1 with approximately 1.0 L; this latter volunteer had not developed a significant vibriocidal immune response to vaccination. Peru-15 shows promise as a single-dose, oral cholera vaccine that is safe, immunogenic, and protective. PMID:7561195

1995-10-01

89

Peptide Nanoparticles as Novel Immunogens: Design and Analysis of a Prototypic Severe Acute Respiratory Syndrome Vaccine  

UK PubMed Central (United Kingdom)

Severe acute respiratory syndrome (SARS) is an infectious disease caused by a novel coronavirus that cost nearly 800 lives. While there have been no recent outbreaks of the disease, the threat...Full Text Available

2009-01-01

90

Passive immunity to feline leukemia: evaluation of immunity from dams naturally infected and experimentally vaccinated.  

UK PubMed Central (United Kingdom)

Antibodies against feline leukemia virus (FeLV) and the feline oncornavirus-associated cell membrane antigen (FOCMA) were transferred from pregnant cats to their suckling kittens. All of these kittens...Full Text Available

1977-04-01

91

LOUSE-BORNE BACTERIAL PATHOGENS IN LICE (PHTHIRAPTERA) OF RODENTS AND CATTLE FROM EGYPT  

Science.gov (United States)

... were erroneous. The oriental rat flea, Xenopsylla cheopis Rothschild, is considered to be the primary vector of ... laboratory and production of Weigl's exanthematous typhus vaccine. In Maintenance of hum...

92

In vitro antigen-induced antibody responses to hepatitis B surface antigen in man. Kinetic and cellular requirements.  

UK PubMed Central (United Kingdom)

In this report we define the parameters of the human immune response after immunization with hepatitis B vaccine. 2 wk after booster immunization, there is significant spontaneous secretion of antibody...Full Text Available

1984-10-01

93

Improvement of a Dendritic Cell-Based Therapeutic Cancer Vaccine with Components of Toxoplasma gondii?  

UK PubMed Central (United Kingdom)

The use of dendritic cells (DCs) as a cellular adjuvant is a promising approach to the immunotherapy of cancer. It has previously been demonstrated that DCs pulsed ex vivo with Toxoplasma gondii...Full Text Available

2009-10-01

94

Immunization of foxes by the intestinal route using an inactivated rabies vaccine.  

UK PubMed Central (United Kingdom)

Approximately 30% of foxes given two doses of an inactivated rabies antigen delivered directly into the intestinal tract developed an immune response as measured by rabies serum neutralizing antibodies....Full Text Available

1989-01-01

95

Genomic Expression Libraries for the Identification of Cross-Reactive Orthopoxvirus Antigens  

UK PubMed Central (United Kingdom)

Increasing numbers of human cowpox virus infections that are being observed and that particularly affect young non-vaccinated persons have renewed interest in this zoonotic disease. Usually causing...Full Text Available

96

Genomic Content of Bordetella pertussis Clinical Isolates Circulating in Areas of Intensive Children Vaccination  

UK PubMed Central (United Kingdom)

BackgroundThe objective of the study was to analyse the evolution of Bordetella pertussis population and the influence of herd immunity in different areas of the...Full Text Available

97

Evaluation of Two Homologous Proline-Rich Proteins of Coccidioides posadasii as Candidate Vaccines against Coccidioidomycosis?  

UK PubMed Central (United Kingdom)

Evaluation of the protective efficacy of recombinant T-cell-reactive proteins of Coccidioides posadasii in a murine model of coccidioidomycosis has led to the discovery of potential...Full Text Available

2007-12-01

98

Emulsified Nanoparticles Containing Inactivated Influenza Virus and CpG Oligodeoxynucleotides Critically Influences the Host Immune Responses in Mice  

UK PubMed Central (United Kingdom)

BackgroundAntigen sparing and cross-protective immunity are regarded as crucial in pandemic influenza vaccine development. Both targets can be achieved by adjuvantation strategy...Full Text Available

99

Dengue virus-specific murine T-lymphocyte proliferation: serotype specificity and response to recombinant viral proteins.  

UK PubMed Central (United Kingdom)

Definition of the T-lymphocyte responses to dengue viruses should aid in the development of safe and effective vaccines and help to explain the pathophysiology of dengue hemorrhagic fever and dengue...Full Text Available

1989-06-01

100

Dengue virus protein recognition by virus-specific murine CD8+ cytotoxic T lymphocytes.  

UK PubMed Central (United Kingdom)

The identification of the protein targets for dengue virus-specific T lymphocytes may be useful for planning the development of subunit vaccines against dengue. We studied the recognition by murine...Full Text Available

1993-02-01

101

CDC - Malaria - Malaria Worldwide - How Can Malaria Cases and...  

Science.gov (United States)

vaccination card during trial enrollment at the KEMRI/CDC site in Kenya. (Alan Rubin, KEMRI) KEMRI Clinical Officer Paul Ogai reviews a prospective participant's...

2011-09-24

102

Auditing the Management of Vaccine-Preventable Disease Outbreaks: The Need for a Tool  

UK PubMed Central (United Kingdom)

Public health activities, especially infectious disease control, depend on effective teamwork. We present the results of a pilot audit questionnaire aimed at assessing the quality of public health services...Full Text Available

104

Evidential and Practical Certainty  

Science.gov (United States)

... We assume that A is chosen so that the claim in question meets whatever are the conventional requirements for confidence in the context at hand. ...

2011-05-14

105

Malnutrition, Gut-Microbial Interactions and Mucosal Immunity to Vaccines, 07 Nov 2011 - 11 Nov 2011, Le Meridien New Delhi, New Delhi, India - SciDe  

Wastenet

... A better understanding of the links between nutrients, the gut microbiome and the intestinal immune system is likely to pave the way to the development of innovative approaches that target activation of specific immunological pathways for promoting the hostrsquo;s gut defense. Such knowledge should positively impact on the development of vaccine formulations and intervention strategies for improved control of enteric infections in developing countries. Registration fees # The Registration Fee is $715.00 on and before September 7, 2011. # After September 7, 2011, the ...

106

Immunological correlates for protection against intranasal challenge of Bacillus anthracis spores conferred by a protective antigen-based vaccine in rabbits.  

Science.gov (United States)

Correlates between immunological parameters and protection against Bacillus anthracis infection in animals vaccinated with protective antigen (PA)-based vaccines could provide surrogate markers to evaluate the putative protective efficiency of immunization in humans. In previous studies we demonstrated that neutralizing antibody levels serve as correlates for protection in guinea pigs (S. Reuveny et al., Infect. Immun. 69:2888-2893, 2001; H. Marcus et al., Infect. Immun. 72:3471-3477, 2004). In this study we evaluated similar correlates for protection by active and passive immunization of New Zealand White rabbits. Full immunization and partial immunization were achieved by single and multiple injections of standard and diluted doses of a PA-based vaccine. Passive immunization was carried out by injection of immune sera from rabbits vaccinated with PA-based vaccine prior to ...

2006-01-01

107

Immunogenicity, efficacy, safety and effectiveness of pneumococcal conjugate vaccines (1998-2006).  

Science.gov (United States)

In this paper we present an overview of the literature on efficacy and safety trials of the various pneumococcal conjugate vaccines on the market (PCV7) and in development (PCV9, PCV11 and allegedly PCV10 and PCV13), as well as of observations from post-licensure studies. Seven- (PCV7) and nine-valent PCV (PCV9) are reported to be sufficiently immunogenic after administration of a 3+1 schedule in infants in various RCTs. PncOMPC (PCV7 with a protein of N. meningitidis as a carrier) is less immunogenic, though this may have no repercussions for the protective efficacy against clinical disease. PCV7 is 82-97% efficacious against vaccine serotype (VT) IPD, 90% efficacious against (clinically diagnosed) pneumococcal pneumonia, and, like the 11-valent PCV, 57% efficacious against VT acute otitis media. Naturally, it would be of paramount public health interest if the same levels of efficacy and effectiveness could be achieved with fewer doses. ...

2006-12-04

108

Genetic control of immune response to pseudorabies and atrophic rhinitis vaccines: II. Comparison of additive direct and maternal genetic effects.  

Science.gov (United States)

Data from 52 litters farrowed in two seasons of a cross-fostering experiment were analyzed to estimate variances and covariances for additive direct and maternal genetic effects on immune response to pseudorabies virus and B. bronchiseptica vaccine. Twenty purebred boars and 44 sows of the Duroc, Landrace and Yorkshire breeds were used. Immune response was measured after vaccine challenge. A modified-live pseudorabies (PR) vaccine was administered to piglets at 28 d of age; response was measured by log2 serum neutralization titers at 56 d. An inactivated B. bronchiseptica bacterin was administered at 28, 42 and 112 d. Antibody levels were measured relative to positive and negative controls at 28, 56 and 119 d by using an enzyme-linked immunosorbent assay (ELISA). Results from this study for heritability were .18 +/- .09 for PR titer and .15 +/- .07 and .52 +/- .15 for 56- and 119-d ELISA values, respectively. The ...

1987-02-01

109

Workshop to identify critical windows of exposure for children's health: neurobehavioral work group summary.  

UK PubMed Central (United Kingdom)

This paper summarizes the deliberations of a work group charged with addressing specific questions relevant to risk estimation in developmental neurotoxicology. We focused on eight questions. a) Does...Full Text Available

2000-06-01

110

The ten questions screen for childhood disabilities: its uses and limitations in Pakistan.  

UK PubMed Central (United Kingdom)

OBJECTIVE--To assess the accuracy of the ten questions screen as a measure of childhood disability for epidemiologic studies in populations lacking resources for professional assessment of children's...Full Text Available

1995-08-01

111

Question box: a tool for gathering information about HIV and AIDS  

UK PubMed Central (United Kingdom)

Previous studies on knowledge of HIV transmission and prevention have used surveys. This study used the question box method to create a safe environment for collecting information on knowledge...Full Text Available

2010-10-01

112

Astronaut Jeff Williams Answers Your Questions  

National Aeronautics and Space Administration (NASA)

Expedition 22 Commander Jeff Williams, aboard the International Space Station 220 miles above Earth, responds to questions posted on YouTube concerning the station's orientation, life in space and the recent butterfly experiment.

2010-03-10

113

Addressing the Question of the Effect of RBC Storage on Clinical Outcomes: The Red Cell Storage Duration Study (RECESS) (Section 7)  

UK PubMed Central (United Kingdom)

The question of whether storage of red blood cells (RBCs) alters their capacity to deliver oxygen and affects patient outcomes remains in a state of clinical equipoise. Studies of the changes...Full Text Available

2010-08-01

114

Simultaneity: A Question of Time, Space, Resources and ...  

Science.gov (United States)

... even divisions. ... hours on 25 October.62 The 82nd Airborne Division and a Marine Amphibious Unit followed the Rangers. ...

2001-05-01

115

Keratoconus: Frequently Asked Questions  

Science.gov (United States)

... a new cornea? As many of you know stem cell research and efforts to develop a replacement cornea have ...

116

Burning questions on the high seas  

Energy Technology Data Exchange (ETDEWEB)

Marine fuels are discussed. Cost, quality, and engineering aspects of burning coal, oil or emulsions of coal and oil are discussed.

1983-02-10

117

Bacterial conjunctivitis  

UK PubMed Central (United Kingdom)

Clinical questionWhat is the best treatment for bacterial conjunctivitis?ResultsTopical antibiotics expedite recovery from bacterial conjunctivitis....Full Text Available

2010-01-01

118

Serotypes and susceptibilities of paediatric clinical isolates of Streptococcus pneumoniae in Crete, Greece, before and after the heptavalent pneumococcal conjugate vaccine.  

Science.gov (United States)

All Streptococcus pneumoniae strains isolated from paediatric clinical samples at Heraklion University General Hospital in the 10-year period 2000-2009 were tested for serotype and susceptibility to antimicrobials. Among a total of 258 strains, 159 were isolated in the 5-year period 2000-2004, before the introduction of the heptavalent pneumococcal conjugate vaccine (PCV7), and 99 in the post-PCV7 5-year period 2005-2009. The prevalence of PCV7-included serotypes decreased in the post-PCV7 period (p?=?0.0002), but an increase was observed for serotypes 7F (p?=?0.002) and 19A (p?=?0.004). Pan-susceptibility rates and susceptibility to cotrimoxazole increased in the post-PCV7 period (p?=?0.01 and p?=?0.008, respectively), but serotype 19A emerged as a contributor to multi-resistance (p?=?0.007). PCV7 was followed by decreased S. pneumoniae resistance and prevalence of vaccine-related serotypes but increased prevalence of serotypes 7F and 19A. ...

2010-07-10

119

Construction and evaluation of a double mutant of Shigella flexneri as a candidate for oral vaccination against shigellosis.  

Science.gov (United States)

Based on studies on the genetic and molecular basis of Shigella flexneri invasive properties, we have constructed and evaluated a double mutant of S. flexneri serotype 5 for utilization as a live attenuated oral vaccine against shigellosis. The first mutation, icsA, blocks intracellular spread of bacteria as well as cell-to-cell infection. It affects the capacity of the invasive pathogen to form large abscesses in epithelia. The second mutation, iuc, eliminates production of the siderophore aerobactin thus impairing growth of the bacterium within tissues. This double mutant, SC5700 appeared safe when administered intragastrically to macaque monkeys as three doses (5 x 10(10) c.f.u. each) at weekly intervals. Protection against a challenge by the wild type isolate (M90T) was observed 4 weeks after the last vaccine inoculation. Duration of carriage was considerably reduced as compared to the control group in which all animals had developed severe ...

1989-10-01

120

Radiation Dosimetry considerations in the safe administration of therapeutic radiopharmaceuticals  

Energy Technology Data Exchange (ETDEWEB)

A set of eight questions was put to advanced nuclear medicine physicians-in-training participating in a continuing assessment exercise in practical therapeutic nuclear oncology. Using the particular example of {sup 131}I-MIBG treatment of neuroblastoma in children, the questions were directed to the rationale of therapy and the contribution of other forms of treatment to toxic effects. The best answer to the questions are reproduced together with an introduction by the examiner, Dr. H. Turner. tabs.

1995-12-01

121

Review on the immunology of European sea bass Dicentrarchus labrax  

British Library Electronic Table of Contents (United Kingdom)

European sea bass (Dicentrarchus labrax L.) is a marine species of great economic importance, particularly in Mediterranean aquaculture. However, numerous pathogenic viruses, bacteria, fungi and parasites affect the species, causing various infectious diseases and thereby leading to the most heavy losses in aquaculture production of sea bass. In this respect, knowledge on molecular and genetic mechanisms of resistance to pathogens and specific features of immune response against various infectious agents should greatly benefit the development of effective vaccines and proper vaccination strategies in marker-assisted selection of fish resistant to a range of infections. To date, genetic knowledge on sea bass immune regulatory genes responsible for resistance to pathogens is relatively poor ...

2007-01-01

122

Intravaginal immunization using the recombinant HIV-1 clade-C trimeric envelope glycoprotein CN54gp140 formulated within lyophilized solid dosage forms  

British Library Electronic Table of Contents (United Kingdom)

Vaccine-mediated prevention of primary HIV-1 infection at the heterosexual mucosal portal of entry may be facilitated by highly optimised formulations or drug delivery devices for intravaginal (i.vag) immunization. Previously we described hydroxyethylcellulose (HEC)-based rheologically structured gel vehicles (RSVs) for vaginal immunization of an HIV-1 vaccine candidate, a soluble recombinant trimeric HIV-1 clade-C envelope glycoprotein designated CN54gp140. Here we investigated the efficacy of lyophilized solid dosage formulations (LSDFs) for prolonging antigen stability and as i.vag delivery modalities. LSDFs were designed and developed that upon i.vag administration they would reconstitute with the imbibing of vaginal fluid to mucoadhesive, site-retentive semi-solids. Mice were immunize...

2011-01-01

123

Cochrane Review: Polysaccharide vaccines for preventing serogroup A meningococcal meningitis  

British Library Electronic Table of Contents (United Kingdom)

AbstractBackground Randomised controlled trials (RCTs) in the 1970s and early 1980s showed the polysaccharide serogroup A vaccine (SgAV) prevented serogroup A meningococcal meningitis (SGAMM). Subsequent non-RCTs suggested significant variations in the age-specific duration of protection among children. Objectives To determine the protective effect, duration of protection, age-specific effects and the effect of booster doses in children of the SgAV against SGAMM. Search strategy We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2010, issue 2) which contains the Acute Respiratory Infections Group's Specialised Register, MEDLINE (January 1950 to May Week 3, 2010) and EMBASE (January 1974 to May 2010). Selection criteria We included RCTs. Non-RCTs ...

2011-01-01

124

Translation products of pre-S(1), pre-S(2) regions and the S gene of hepatitis B virus: susceptibility of their antigenic activities to treatment with heat, urea formalin or pepsin  

UK PubMed Central (United Kingdom)

Hepatitis B subviral particles, purified from plasma of asymptomatic carriers seropositive for hepatitis B e antigen, were treated with various conditions reported for the processing of vaccines. Thereafter,...Full Text Available

1986-12-01

125

Serum and salivary responses to oral tetravalent reassortant rotavirus vaccine in newborns.  

UK PubMed Central (United Kingdom)

Serum and salivary responses of 95 infants to either a standard (4 x 10(4) plaque-forming units (PFU), 47 neonates) or a high dose (4 x 10(5) PFU, 48 neonates) of tetravalent reassortant rhesus rotavirus...Full Text Available

1993-05-01

126

Safety and immunogenicity of ERA strain of rabies virus propagated in a BHK-21 cell line.  

UK PubMed Central (United Kingdom)

The ERA strain of rabies virus was propagated in a baby hamster kidney cell line (BHK-21/C13). The viral titer was 10(1.8) tissue culture infective doses (TCID) higher than that of commercial ERA vaccine....Full Text Available

1989-10-01

127

Recruitment of intestinal CD45RA+ and CD45RC+ cells induced by a candidate oral vaccine against porcine post-weaning colibacillosis.  

Science.gov (United States)

To assess the influence of a live attenuated oral vaccine against porcine post-weaning colibacillosis (PWC) induced by enterotoxigenic Escherichia coli (ETEC) on mucosal lymphoid cell CD45 isoforms expression, experimental group of weaned pigs (n=6) was immunized orally with F4ac+ non-ETEC strain (day 0) and challenged with F4ac+ ETEC strain 7 days latter. Non-immunized ETEC-infected pigs (n=6) served as control. All pigs were killed on post-challenge day 7. The small intestine was excised for isolation of jejunal lamina propria (JLP) and ileal Peyer's patch (IPP) lymphocytes and immunohistochemical studies. The results obtained by immunophenotyping of isolated cells show that the proportion of CD45RA+ and CD45RC+ JLP, but not IPP, cells were higher in the non-ETEC-immunized ETEC-infected pigs versus non-immunized infected. Additionally, while CD45RA+ JLP cells increased only slightly, the expression of CD45RC isoform on the JLP cells was significantly higher ...

2002-07-01

128

Murine antibody response to oral infection with live aroA recombinant Salmonella dublin vaccine strains expressing filamentous hemagglutinin antigen from Bordetella pertussis.  

Science.gov (United States)

Two plasmids which express either nearly intact or truncated filamentous hemagglutinin (FHA) from Bordetella pertussis and which are marked with a tetracycline resistance (Tcr) gene were transformed into Salmonella dublin SL1438, an aroA deletion mutant intended for use as an attenuated oral vaccine against salmonellosis. These S. dublin recombinants, when fed to mice, induced serum immunoglobulin, immunoglobulin M (IgM), and sometimes IgA antibody responses to FHA and S. dublin. In addition, IgA antibodies against FHA were found in gut wash fluids. S. dublin carrying pDB2300, a multicopy plasmid encoding truncated FHA protein, induced a better antibody response than did S. dublin carrying pDB2000, a low-copy-number plasmid encoding full-sized FHA. Administration of tetracycline to mice enhanced the stability of recombinant plasmids, and tetracycline-treated mice developed higher anti-FHA titers. Although neither strain examined is suitable for use in a human oral ...

1990-08-01

129

Invasiveness and persistence of Salmonella enteritidis, Salmonella typhimurium, and a genetically defined S. enteritidis aroA strain in young chickens.  

UK PubMed Central (United Kingdom)

Newly hatched chicks were dosed orally with a Salmonella typhimurium wild-type strain, an S. enteritidis wild-type strain, and a genetically defined S. enteritidis aroA vaccine candidate, strain CVL30....Full Text Available

1994-11-01

130

Interferon-? expressed by a rabies virus-based HIV-1 vaccine vector serves as a molecular adjuvant and decreases pathogenicity  

UK PubMed Central (United Kingdom)

Type I interferon is important in anti-viral responses and in coordinating the innate immune response. Here we explore the use of interferon-β to adjuvant the response to a rabies virus...Full Text Available

2008-12-20

131

Induction of Antibody Responses to African Horse Sickness Virus (AHSV) in Ponies after Vaccination with Recombinant Modified Vaccinia Ankara (MVA)  

UK PubMed Central (United Kingdom)

BackgroundAfrican horse sickness virus (AHSV) causes a non-contagious, infectious disease in equids, with mortality rates that can exceed 90% in susceptible horse populations....Full Text Available

132

Helper T-Cell Epitopes Encoded by the Babesia bigemina rap-1 Gene Family in the Constant and Variant Domains Are Conserved among Parasite Strains  

UK PubMed Central (United Kingdom)

Among important candidates for babesial vaccines are apical complex proteins, including rhoptry-associated protein 1 (RAP-1) from Babesia bovis and B. bigemina, which...Full Text Available

1998-04-01

133

Differential Specificity and Immunogenicity of Adenovirus Type 5 Neutralizing Antibodies Elicited by Natural Infection or Immunization?  

UK PubMed Central (United Kingdom)

A recent clinical trial of a T-cell-based AIDS vaccine delivered with recombinant adenovirus type 5 (rAd5) vectors showed no efficacy in lowering viral load and was associated with increased risk of...Full Text Available

2010-01-01

134

A progress for the health of south countries. The solar refrigerator; Un progres pour la sante dans les pays du Sud. Le refrigerateur solaire  

Energy Technology Data Exchange (ETDEWEB)

In order to conserve vaccines in hot countries a solar refrigerator has been made by a French university. It is a photothermal refrigerator without batteries. It uses two gases: ammonia and calcium chloride. The refrigerator is autonomous and can work eleven days without sun. (N.C.)

1998-05-01

135

BWR stability analysis at Brookhaven National Laboratory  

Energy Technology Data Exchange (ETDEWEB)

Following the unexpected, but safely terminated, power and flow oscillations in the LaSalle-2 Boiling Water Reactor (BWR) on March 9, 1988, the Nuclear Regulatory Commission (NRC) Offices of Nuclear Reactor Regulation (NRR) and of Analysis and Evaluation of Operational Data (AEOD) requested that the Office of Nuclear Regulatory Research (RES) carry out BWR stability analyses, centered around fourteen specific questions. Ten of the fourteen questions address BWR stability issues in general and are dealt with in this paper. The other four questions address local, out-of-phase oscillations and matters of instrumentation; they fall outside the scope of the work reported here. It was the purpose of the work documented in this report to answer ten of the fourteen NRC-stipulated questions. Nine questions are answered by analyzing the LaSalle-2 instability and related BWR transients with ...

1991-12-31

136

A strategy for managing customer relations on the internet: evidence from the football sector  

British Library Electronic Table of Contents (United Kingdom)

Purpose - The purpose of this paper is to provide a better understanding of how the internet is used as a strategic tool in electronic customer relationship management (e-CRM) in the football sector. In particular, the research questions this paper addresses are: How can the online environment be described? How are the customers served in this online environment? The first research question provides an overview of the online environment and the second research question describes the services offered in this online environment. Design/methodology/approach - The qualitative research is the appropriate approach, in order to collect the required data, as the particular research characterizes a complete and comprehensive view and understanding of a phenomenon in its entity. The research is base...

2009-01-01

137

Unearthing the Phylogenetic Roots of Sleep  

UK PubMed Central (United Kingdom)

Why we sleep remains one of the enduring unanswered questions in biology. At its core, sleep can be defined behaviorally as a homeostatically regulated state of reduced movement and sensory...Full Text Available

2008-08-05

138

Questions in 'Arts, Music & Literature' NASA Be A ... - Be a Martian  

Science.gov (United States)

is that Martians, Alliens has a Supernatural Power, Mental Mediumship, Mental Clairvoyant, Mental Telepathy just like me that could Heard the Illegal ...

139

Questions and Answers on Changes to the Renewable Fuel Standard...  

Science.gov (United States)

fuel obligation under the RFS2 program for the production or importation of conventional jet fuel, RINs can be generated for renewable jet fuel. Is that right? A: As described in...

2011-08-18

140

Perspectives in radiation and health: reflections on the International Conference in Beer Sheva.  

UK PubMed Central (United Kingdom)

Insofar as international conferences reflect the state of development of the subject under discussion, they provide an opportunity to question, at a rather fundamental level, the direction of and progress...Full Text Available

1997-12-01

141

OHCM QUESTION AND ANSWERING SYSTEM  

Science.gov (United States)

Jun 6, 2011... applied first (depending upon whether the employee is exempt or non-exempt) before applying the provisions of compensatory time travel. ...

142

Naltrexone and Combined Behavioral Intervention Effects on Trajectories of Drinking in the COMBINE study  

UK PubMed Central (United Kingdom)

ObjectiveCOMBINE is the largest study of pharmacotherapy for alcoholism in the United States to date, designed to answer questions about the benefits of combining...Full Text Available

2010-03-01

143

Media Availability in Hanoi, Vietnam  

Science.gov (United States)

that needs to change is the ambiguity in the laws themselves. QUESTION: The issue of WikiLeaks raised? DEPUTY ASSISTANT SECRETARY BAER: It was not. It was raised by the students....

2011-09-18

144

In Defense of Change Processes  

UK PubMed Central (United Kingdom)

Nativist and constructivist approaches to the study of development share a common emphasis on characterizing beginning and end states in development. This focus has highlighted the question...Full Text Available

2008-01-01

145

Frequent Questions - Emissions | Climate Change | U.S. EPA  

Science.gov (United States)

activities, including the combustion of diesel fuel in heavy-duty vehicles and jet fuel in aircrafts. Current details on emissions from the transportation and other...

2011-04-14

146

Does Your Class Have Questions About Earthquakes? - NASA Jet ...  

Science.gov (United States)

Mar 15, 2011 ... The NASA/JPL Education Office works with educators -- both classroom teachers and informal educators -- to provide tools, resources and ...

147

Colonoscopy  

Medline Plus

... experts agree-- a colonoscopy is the most accurate test to detect the cancer, but because of cost ... method. Dr. Randall Burt: Colonoscopy is the best test. The question is therefore shouldn't everyone, since ...

148

Clinical significance of coagulase-negative staphylococci.  

UK PubMed Central (United Kingdom)

Although coagulase-negative staphylococci (C-NS) have been implicated in certain human infections, they are generally regarded as contaminants, and their clinical significance is questioned. To assess...Full Text Available

1982-08-01

149

CFSAN - Questions and Answers on FDA's Import Alert on Farm-Raised ...  

Science.gov (United States)

... Program on nitrofurans. Nitrofurazone (TR-337 published in June 1988) and Nitrofurantoin (TR-341 published in Sept 1989). Both of ...

150

CDC - XMRV Home - XMRV  

Science.gov (United States)

For more information about this message, please visit this page: About CDC.gov. XMRV (Xenotropic Murine Leukemia Virus-related Virus) XMRV Home Questions & Answers Updates...

2011-10-16

151

Biosynthesis of hyaluronan: direction of chain elongation  

UK PubMed Central (United Kingdom)

The mechanism of hyaluronan biosynthesis in vertebrates had been proposed to occur at the reducing end of growing chains. This mechanism was questioned because a recombinant synthase appeared to add...Full Text Available

2006-09-15

152

Asia's New High Tech Competitors  

Science.gov (United States)

Implications for the United States Last modified on September 13,1995. Please send questions and/or comments about these pages to srsweb@nsf.gov.

153

Efficient mitigation strategies for epidemics in rural regions  

CERN Document Server

Containing an epidemic at its origin is the most desirable mitigation. Epidemics have often originated in rural areas, with rural communities among the first affected. Disease dynamics in rural regions have received limited attention, and results of general studies cannot be directly applied since population densities and human mobility factors are very different in rural regions from those in cities. We create a network model of a rural community in Kansas, USA, by collecting data on the contact patterns and computing rates of contact among a sampled population. We model the impact of different mitigation strategies detecting closely connected groups of people and frequently visited locations. Within those groups and locations, we compare the effectiveness of random and targeted vaccinations using a Susceptible-Exposed-Infected-Recovered compartmental model on the contact network. Our simulations show that the targeted vaccinations of only 10% ...

2010-01-01

154

PhET Teacher Ideas and Activities: Images from Convex Lenses  

Science.gov (United States)

This is an inquiry-based module created specifically for use with the PhET simulation Geometric Optics. It includes a lesson plan for teaching about convex lenses, step-by-step student directions, and a set of Power Point "clicker" questions for use as warm-up questions or informal assessment. This resource is part of a larger collection of interactive Java simulations for students of physics, developed by the Physics Education Technology project at the University of Colorado.

2009-05-20

155

Methanol, MTBE suppliers will likely keep up with rising demand  

Energy Technology Data Exchange (ETDEWEB)

A primary and basic question prevails in the methanol industry - What will be the global demand for methanol, for the expanded production of methyl tertiary butyl ether (MTBE), during the next few years This article attempts to answer the question by discussing the global market; supply and demand factors; the market in North America, Western Europe, Far East and Asia, South America, and other regions; and the uncertainties that remain.

1993-03-29

156

Large cardinals with few measures  

CERN Document Server

We show, assuming the consistency of one measurable cardinal, that it is consistent for there to be exactly kappa+ many normal measures on the least measurable cardinal kappa. This answers a question of Stewart Baldwin. The methods generalize to higher cardinals, showing that the number of lambda strong compactness or lambda supercompactness measures on P_kappa(lambda) can be exactly lambda+, if lambda>kappa is a regular cardinal. We conclude with a list of open questions. Our proofs use a critical observation due to James Cummings.

2006-01-01

157

How common are Earths? How common are Jupiters?  

CERN Document Server

Among the billions of planetary systems that fill the Universe, we would like to know how ours fits in. Exoplanet data can already be used to address the question: How common are Jupiters? Here we discuss a simple analysis of recent exoplanet data indicating that Jupiter is a typical massive planet rather than an outlier. A more difficult question to address is: How common are Earths? However, much indirect evidence suggests that wet rocky planets are common.

2002-01-01

158

Detector questions for a gamma-gamma collider  

Energy Technology Data Exchange (ETDEWEB)

The working group reviewed the main difficulties foreseen in doing physics at a gamma-gamma collider. They discussed the requirements for the detector, calculated some of the signal and background rates, compared methods of measuring luminosity, looked at how to get the laser beams in, investigated ways of sweeping aside the electrons and considered ways of disposing of the used beams. No overwhelming obstacles were found but important questions still need to be answered. ((orig.)).

1995-02-01

159

Detector questions for a gamma-gamma collider  

International Nuclear Information System (INIS)

The working group reviewed the main difficulties foreseen in doing physics at a gamma-gamma collider. They discussed the requirements for the detector, calculated some of the signal and background rates, compared methods of measuring luminosity, looked at how to get the laser beams in, investigated ways of sweeping aside the electrons and considered ways of disposing of the used beams. No overwhelming obstacles were found but important questions still need to be answered. ((orig.)).

160

Clinical aspects of Marburg hemorrhagic fever  

British Library Electronic Table of Contents (United Kingdom)

Marburg virus belongs to the genus Marburgvirus in the family Filoviridae and causes a severe hemorrhagic fever, known as Marburg hemorrhagic fever (MHF), in both humans and nonhuman primates. Similar to the more widely known Ebola hemorrhagic fever, MHF is characterized by systemic viral replication, immunosuppression and abnormal inflammatory responses. These pathological features of the disease contribute to a number of systemic dysfunctions including hemorrhages, edema, coagulation abnormalities and, ultimately, multiorgan failure and shock, often resulting in death. A detailed understanding of the pathological processes that lead to this devastating disease remains elusive, a fact that contributes to the lack of licensed vaccines or effective therapeutics. This article will review the...

2011-01-01

161

Sensitivity of Shallow Land Burial to neutron environment and activation cross sections in IFE thick-liquid concepts  

International Nuclear Information System (INIS)

A comprehensive assessment on the eligibility of reduced activation (RA) steels as structural chamber material in Inertial Fusion Energy thick-liquid concepts is performed. As far as alloying elements, it is shown that the activation of tungsten is a question to discuss. Regarding impurity elements, it is analyzed if they could question the possibility of obtaining real RA steels for shallow land burial (SLB). The effect of the thickness of the liquid wall on the SLB response of alloying and impurity elements is computed. It seems that a reasonable liquid thickness of about 80 cm is allowable to obtain SLB acceptability of real RA steels. And above all, we have estimated the impact of cross section uncertainties when addressing the former questions, and we identify those to be improved. The necessary improvement of some tungsten and niobium cross sections is justified. (authors)

2006-06-01

162

XML Questions to consider  

Indian Academy of Sciences (India)

are you exchanging data or metadata through specific agreements with a defined number of partners? or are you intending to make data or metadata available in a more "open" environment, with the expectation that it may be used by a potentially unlimited number of services? ...

163

Utilization of a Marketing Strategy at Naval Regional Medical Center Great Lakes, Great Lakes, Illinois.  

Science.gov (United States)

The study examines the question of whether or not civilian marketing practices and principles can be applied in the military care setting. Using the NRMC Great Lakes as a basis, the answer is yes--consumers of military medical care are ready to be the rec...

1983-01-01

164

Use of a questionnaire to obtain an alcohol history from those attending an inner city accident and emergency department.  

UK PubMed Central (United Kingdom)

A screening questionnaire designed to take an alcohol history was used on 996 patients attending the London Hospital Accident and Emergency Department. Questions concerned with 'binge' drinking detected...Full Text Available

1989-03-01

165

Topographic Map Creation  

Science.gov (United States)

In this activity, students create two- and three-dimensional maps by using a data grid of an imaginary section of Earth's surface. They are challenged to create six different maps of various surface features and answer questions about them.

2005-01-01

166

The Role of the Pattern Edge in Goldfish Visual Motion Detection  

UK PubMed Central (United Kingdom)

To understand the function of edges in perception of moving objects, we defined four questions to answer. Is the focus point in visual motion detection of a moving object: (1) the body or the edge of...Full Text Available

2010-12-01

167

The NAS Perchlorate Review: Questions Remain about the Perchlorate RfD  

UK PubMed Central (United Kingdom)

Human exposure to perchlorate is commonplace because it is a contaminant of drinking water, certain foods, and breast milk. The U.S. Environmental Protection Agency (EPA) conducted a perchlorate risk...Full Text Available

2005-09-01

168

The French national prospective cohort of patients co-infected with HIV and HCV (ANRS CO13 HEPAVIH): Early findings, 2006-2010  

UK PubMed Central (United Kingdom)

BackgroundIn France, it is estimated that 24% of HIV-infected patients are also infected with HCV. Longitudinal studies addressing clinical and public health questions related to...Full Text Available

169

Student Understanding of the First and Second Laws of Thermodynamics  

Science.gov (United States)

This presentation from the 2006 PTEC Conference presents education research on topics in thermodynamics. Student responses to conceptual thermodynamics questions, and the conceptions they reveal, are presented. Tutorial materials developed to help students gain a better understanding of the topic are also presented.

2006-09-30

170

Status of electron accelerators for linear colliders  

Energy Technology Data Exchange (ETDEWEB)

The paper outlines the basic problems concerning creation of electron-positron linear colliders, as well as their present-day status. More details on the question can be found in the proceedings of recent workshops on linear colliders contained in the References. ((orig.)).

1995-02-01

171

Some open questions in nuclear physics  

Energy Technology Data Exchange (ETDEWEB)

A review of recent work in nuclear physics is presented. The paper gives a broad discussion of research goals in nuclear structure, quark-gluon degrees of freedom, quark-gluon plasma, symmetries, and rare decays. (DWL)

1986-10-01

172

Remarks En Route Abu Dhabi, United Arab Emirates  

Science.gov (United States)

QUESTION: You've already had one trip where you went to deal with fallout from WikiLeaks. You are visiting a couple of places where the leaders were quoted saying some very...

2011-09-18

173

Purpose and regulation of stem cells: a systems-biology view from the Caenorhabditis elegans germ line  

UK PubMed Central (United Kingdom)

Stem cells are expected to play a key role in the development and maintenance of organisms, and hold great therapeutic promises. However, a number of questions must be answered to achieve an...Full Text Available

2009-01-01

174

Problems for clinical judgement: 2. Obtaining a reliable past medical history  

UK PubMed Central (United Kingdom)

ORDINARY HUMAN REASONING MAY LEAD PATIENTS to provide an unreliable history of past experiences because of errors in comprehension, recall, evaluation and expression. Comprehension of a question may...Full Text Available

2001-03-20

175

On the type and the standardform of induced UA representations  

International Nuclear Information System (INIS)

The author derives to which of the three types an irreducible UA representation which is obtained with the procedure of generalised induction belongs. The question whether or not the irreducible induced UA representations are on standardform is analysed. The results hold as well for induced PUA representations. (Auth.).

176

Mind Operational Semantics and Brain Operational Architectonics: A Putative Correspondence  

UK PubMed Central (United Kingdom)

Despite allowing for the unprecedented visualization of brain functional activity, modern neurobiological techniques have not yet been able to provide satisfactory answers to important questions about...Full Text Available

177

Maximum capacity of steam turbine units  

International Nuclear Information System (INIS)

The author investigates the question of the maximum capacity of steam turbines in nuclear power plants when towards the end of the nineties turbo-generator units of 3,000 MW and more will be necessary as a result of increased energy demand. (TK).

178

Massive turnover of functional sequence in human and other mammalian genomes  

UK PubMed Central (United Kingdom)

Despite the availability of dozens of animal genome sequences, two key questions remain unanswered: First, what fraction of any species' genome confers biological function, and second, are apparent...Full Text Available

2010-10-01

179

Low-Level Exposure to Multiple Chemicals: Reason for Human Health Concerns?  

UK PubMed Central (United Kingdom)

BackgroundA key question in the risk assessment of exposures to multiple chemicals is whether mixture effects may occur when chemicals are combined at low doses which individually...Full Text Available

2007-12-01

180

Learn CPR You Can Do It!  

Science.gov (United States)

Have a question about CPR? Click Here To Ask The Doctor Learn CPR is a free public service supported by the University of Washington School of Medicine . Learn the basics of CPR - cardiopulmonary resuscitation. The American Heart Association issued updated ...

181

Ion clustering in aqueous solutions probed with vibrational energy transfer  

UK PubMed Central (United Kingdom)

Despite prolonged scientific efforts to unravel the hydration structures of ions in water, many open questions remain, in particular concerning the existences and structures of ion clusters in 1∶1...Full Text Available

2011-03-22

182

Induction or hysteresis: That is the cooktop question  

Science.gov (United States)

For many years one of us has cooked on an induction cooktop and been impressed by its efficiency, cleanliness, and responsiveness. The commercial name ``induction'' cooktop suggests that we have here an application of Faraday's law of electromagnetic induction since the cooktop produces an oscillating magnetic field.

2001-02-01

183

Induction of tumors by screening mammography  

International Nuclear Information System (INIS)

Somatic radiation doses are recognized to be possible factors of carcinogenesis. In correctly performed mammography, however, even as screening test, the radiation dose does not reach such an order of magnitude that the benefit of the procedure as to prevention of breast cancer is called into question.

1983-01-01

184

FAQ: Earthquakes, Faults, Plate Tectonics, Earth Structure  

Science.gov (United States)

This frequently-asked-questions feature provides answers about earthquakes, faults, plate tectonics, and earth structure. Maps and diagrams are provided with some answers, and links to additional information and to related topics are included.

185

Evidence for nonrandom hydrophobicity structures in protein chains.  

UK PubMed Central (United Kingdom)

The question of whether proteins originate from random sequences of amino acids is addressed. A statistical analysis is performed in terms of blocked and random walk values formed by binary hydrophobic...Full Text Available

1996-09-03

186

Evaluating professionalism in medical undergraduates using selected response questions: findings from an item response modelling study  

UK PubMed Central (United Kingdom)

BackgroundProfessionalism is a difficult construct to define in medical students but aspects of this concept may be important in predicting the risk of postgraduate misconduct. For...Full Text Available

187

Effects of small doses of ionizing radiation on human health  

Energy Technology Data Exchange (ETDEWEB)

The risks to human health from small doses of ionizing radiation raise questions which remain largely unanswered. This paper begins by explaining the historical background to this subject; it goes on to discuss recent developments and concludes with a personal view of the dose-reponse relationship. (author).

1997-12-01

188

Effects of small doses of ionizing radiation on human health  

International Nuclear Information System (INIS)

The risks to human health from small doses of ionizing radiation raise questions which remain largely unanswered. This paper begins by explaining the historical background to this subject; it goes on to discuss recent developments and concludes with a personal view of the dose-reponse relationship. (author).

1997-01-01

189

Economic Factors and Relationship Quality Among Young Couples: Comparing Cohabitation and Marriage  

UK PubMed Central (United Kingdom)

Are economic resources related to relationship quality among young couples, and to what extent does this vary by relationship type? To answer these questions, we estimated regression models...Full Text Available

2010-10-01

190

Der beschleunigte Fortschritt  

CERN Multimedia

Since 50 years, the scientists in European Center for Nuclear Research in Geneva, are looking for the secrets of the nature. Their standard Model would explains a lot of things; but the single question "What is the mass?" still does not have an answer

2004-01-01

191

Current algebra and gauge variance  

Energy Technology Data Exchange (ETDEWEB)

It is urged that the lesson of gauge invariance in quantum electrodynamics implies the irrelevance of `Schwinger term` difficulties in current algebra. The divergence equations of Veltman form the basis of a gauge-variation formalism in which these questions are avoided. (author). 9 refs.

1995-12-31

192

Computational approaches to discovering semantics in molecular biology  

Energy Technology Data Exchange (ETDEWEB)

One of the central questions of molecular biology is the discovery of the semantics of DNA. This discovery relies in a critical way on a variety of expensive computations. In order to solve these computations, both parallel computers and special-purpose hardware play a major role.

1989-07-01

193

Clostridium difficile is not associated with outbreaks of viral gastroenteritis in the elderly in the Netherlands  

UK PubMed Central (United Kingdom)

The coincidental increase in norovirus outbreaks and Clostridium difficile infection (CDI) raised the question of whether these events could be related, e.g. by enhancing spread by...Full Text Available

2010-06-01

194

Chronic Fatigue: Can Natural Remedies Boost My Energy?  

Science.gov (United States)

... Question Chronic fatigue: Can natural remedies boost my energy? Are there any natural remedies that reduce chronic ... AN01764 ">Chronic fatigue: Can natural remedies boost my energy? Guidelines for sites linking to MayoClinic.com ...

195

Chromosomal sites for hepatitis B virus integration in human hepatocellular carcinoma.  

UK PubMed Central (United Kingdom)

The discovery that hepatitis B virus (HBV) integrates into host chromosomes raises the question of whether such viral DNA integration correlates directly with the activation of specific oncogenes or...Full Text Available

1991-12-01

196

Bayesian Cue Integration as a Developmental Outcome of Reward Mediated Learning  

UK PubMed Central (United Kingdom)

Average human behavior in cue combination tasks is well predicted by Bayesian inference models. As this capability is acquired over developmental timescales, the question arises, how it is learned....Full Text Available

197

Asking the right questions: Scoping studies in the commissioning of research on the organisation and delivery of health services  

UK PubMed Central (United Kingdom)

Scoping studies have been used across a range of disciplines for a wide variety of purposes. However, their value is increasingly limited by a lack of definition and clarity of purpose. The UK's Service...Full Text Available

198

Aquatic Resource Monitoring  

Wastenet

...research strategy and plans Aquatic resource monitoring research programs, EMAP and STAR grants Go To EMAP homepage Go To Top Bibliography References for survey designs, statistical analyses , program documentation, and monitoring reports. Reports, abstracts and links to electronic versions Go To Top Frequently Asked Questions ...

199

Ambassade Des Etats-Unis Kinshasa, Congo - Accueil  

Science.gov (United States)

sur la médiatisation des élections Il s'est ouverte le 16 septembre 2011 à Matadi dans le Bas-Congo une formation sur la médiatisation des questions électorales,...

2011-10-13

200

A rational vision of stratospheric ozone  

Energy Technology Data Exchange (ETDEWEB)

This work deals with a rational vision of stratospheric ozone including the threats on ozone layer, the verifications and the fears. After a recalling on the ozone layer history, the authors treats the question of the ultraviolets particularly the beneficial effects. Then an explanation of the ozone layer decrease is given. (O.L.). 29 refs., 6 figs.

1995-03-01

201

A History of Spike-Timing-Dependent Plasticity  

UK PubMed Central (United Kingdom)

How learning and memory is achieved in the brain is a central question in neuroscience. Key to today’s research into information storage in the brain is the concept of synaptic plasticity, a...Full Text Available

202

A Beautiful Day in the Neighborhood: An Event-Related Potential Study of Lexical Relationships and Prediction in Context  

UK PubMed Central (United Kingdom)

Two related questions critical to understanding the predictive processes that come online during sentence comprehension are 1) what information is included in the representation created through...Full Text Available

2009-10-01

203

Mathematical Problem-Solving and Ontology: An Exercise  

British Library Electronic Table of Contents (United Kingdom)

In this paper the reader is asked to engage in some simple problem-solving in classical pure number theory and to then describe, on the basis of a series of questions, what it is like to solve the problems. In the recent philosophy of mind this ?what is it like? question is one way of signaling a turn to phenomenological description. The description of what it is like to solve the problems in this paper, it is argued, leads to several morals about the epistemology and ontology of classical pure mathematical practice. Instead of simply making philosophical judgments about the subject matter in advance, the exercise asks the reader to briefly engage in a mathematical practice and to then reflect on the practice.

2010-01-01

204

Science and Technology Review July/August 2010  

Energy Technology Data Exchange (ETDEWEB)

This issue has the following articles: (1) Deterrence with a Minimum Nuclear Stockpile - Commentary by Bruce T. Goodwin; (2) Enhancing Confidence in the Nation's Nuclear Stockpile - Livermore experts are participating in a national effort aimed at predicting how nuclear weapon materials and systems will likely change over time; (3) Narrowing Uncertainties - For climate modeling and many other fields, understanding uncertainty, or margin of error, is critical; (4) Insight into a Deadly Disease - Laboratory experiments reveal the pathogenesis of tularemia in host cells, bringing scientists closer to developing a vaccine for this debilitating disease. (5) Return to Rongelap - On the Rongelap Atoll, Livermore scientists are working to minimize radiological exposure for natives now living on or wishing to return to the islands.

2010-05-27

205

Novel Techniques and Their Wide Applications to Health Foods, Medical and Agricultural Biotechnology in Relation to Policy Making on Genetically Modified Crops and Foods  

CERN Document Server

Selected applications of novel techniques in Agricultural Biotechnology, Health Food formulations and Medical Biotechnology are being reviewed with the aim of unraveling future developments and policy changes that are likely to open new markets for Biotechnology and prevent the shrinking or closing of existing ones. Amongst the selected novel techniques with applications in both Agricultural and Medical Biotechnology are: immobilized bacterial cells and enzymes, microencapsulation and liposome production, genetic manipulation of microorganisms, development of novel vaccines from plants, epigenomics of mammalian cells and organisms, and biocomputational tools for molecular modeling related to disease and Bioinformatics. Both fundamental and applied aspects of the emerging new techniques are being discussed in relation to their anticipated, marked impact on future markets and present policy changes that are needed for success in either Agricultural or Medical ...

2004-01-01

206

Methanogen community structure in the rumens of farmed sheep, cattle and red deer fed different diets  

British Library Electronic Table of Contents (United Kingdom)

Abstract Development of inhibitors and vaccines that mitigate rumen-derived methane by targeting methanogens relies on knowledge of the methanogens present. We investigated the composition of archaeal communities in the rumens of farmed sheep (Ovis aries), cattle (Bos taurus) and red deer (Cervus elaphus) using denaturing gradient gel electrophoresis (DGGE) to generate fingerprints of archaeal 16S rRNA genes. The total archaeal communities were relatively constant across species and diets, and were less variable and less diverse than bacterial communities. There were diet- and ruminant-species-based differences in archaeal community structure, but the same dominant archaea were present in all rumens. These were members of three coherent clades: species related to Methanobrevibacter ruminan...

2011-01-01

207

Low cytotoxicity effect of dendrosome as an efficient carrier for rotavirus VP2 gene transferring into a human lung cell line  

British Library Electronic Table of Contents (United Kingdom)

The efficiency of dendrosome (a gene porter) was assessed in transferring recombinant human rotavirus VP2 cDNA into A549, a human lung cell line. After gene transferring, transmission electron microscopy showed core-like particles (CLPs) formation in the transfected cells both with dendrosome and lipofectamine porters. In addition, western blotting analysis showed that the expression of VP2 gene was almost equal in the dendrosome and lipofectamine-transfected cells. Also, the cytotoxicity studies revealed that dendrosome had a lower cytotoxicity than lipofectamine. Therefore, our study may introduce dendrosome as a possible carrier for gene transferring into the human lung cell line, especially, for intranasally administration of DNA vaccines.

2009-01-01

208

Global suppression of mitogen-activated ovine peripheral blood mononuclear cells by surface protein activity from Mycoplasma ovipneumoniae  

British Library Electronic Table of Contents (United Kingdom)

Mycoplasma ovipneumoniae is associated with chronic non-progressive pneumonia of sheep and goats. As with many other mycoplasmas involved in animal diseases, protective immune responses have not been achieved with vaccines, even though antibody responses can be obtained. This study focuses on characterizing the interaction of M. ovipneumoniae with ovine PBMC using carboxy-fluorescein-succinimidyl-ester (CFSE) loading and flow cytometry to measure lymphoid cell division. M. ovipneumoniae induced a strong in vitro polyclonal suppression of CD4^+, CD8^+, and B blood lymphocyte subsets. The suppressive activity could be destroyed by heating to 60^oC, and partially impaired by formalin and binary ethyleneimine treatment that abolished its viability. The activity resided on the surface-exposed m...

2010-01-01

209

Estimates of quantitative genetic parameters of immunological traits in the chicken.  

Science.gov (United States)

Three in vivo assays were used to measure the immunocompetence of chickens in two generations of a selection experiment. The obtained data were used to estimate the variance components for sire and dam for antibody production to Pasteurella multocida and Mycoplasma gallisepticum vaccines, for T-cell-mediated immunity evaluated by a phytohemagglutinin wing web assay, and for clearance of foreign particles from the circulatory system. Heritabilities of and genetic correlations among these immunological traits were calculated from the sire variance components. Heritability estimates of the immunological traits based on the sire component of variance ranged from .06 to .53, and genetic correlations among immunological traits were generally negative. PMID:1956847

1991-10-01

210

Diphtheria toxoid conformation in the context of its nanoencapsulation within liposomal particles sandwiched by chitosan  

British Library Electronic Table of Contents (United Kingdom)

Chitosan (a?-(1-4)-amino-2-deoxy-b?-D-glucan) is a deacetylated form of chitin, a polysaccharide from crustacean shells. Its unique characteristics, such as positive charge, biodegradability, biocompatibility, nontoxicity, and rigid structure, make this macromolecule ideal for an oral vaccine delivery system. We prepared reverse-phase evaporation vesicles (REVs) sandwiched by chitosan (Chi) and polyvinylic alcohol (PVA). However, in this method, there are still some problems to be circumvented related to protein stabilization. During the inverted micelle phase of protein nanoencapsulation, hydrophobic interfaces are expanded, leading to interfacial adsorption, followed by protein unfolding and aggregation. Here, spectroscopic and immunological techniques were used to ascertain the effects ...

2011-01-01

211

Complete genome sequences of Brucella melitensis strains M28 and M5-90, with different virulence backgrounds.  

Science.gov (United States)

Brucella melitensis is a Gram-negative coccobacillus bacteria belonging to the Alphaproteobacteria subclass. It is an important zoonotic pathogen that causes brucellosis, a disease affecting sheep, cattle, and sometimes humans. The B. melitensis strain M5-90, a live attenuated vaccine cultured from the B. melitensis virulent strain M28, has been an effective tool to control brucellosis in goats and sheep in China. Here we report the complete genome sequences of B. melitensis M28 and M5-90, strains with different virulence backgrounds, which will serve as a valuable reference for future studies. PMID:21478357

2011-04-08

212

Chloroquine for influenza prevention: a randomised, double-blind, placebo controlled trial  

British Library Electronic Table of Contents (United Kingdom)

Background: Chloroquine has in-vitro activity against influenza and could be an ideal candidate for worldwide prevention of influenza in the period between onset of a pandemic with a virulent influenza strain and the development and widespread dissemination of an effective vaccine. We aimed to assess the efficacy of such an intervention. Methods: In this randomised, double-blind, placebo-controlled trial done at a single centre in Singapore, we randomly assigned (1:1) healthy adults to receive chloroquine phosphate (500 mg/day for 1 week, then once a week to complete 12 weeks) or matching placebo by use of a computer-generated randomisation list. Participants filled an online symptom diary every week, supplemented by daily diaries and self-administered nasal swabs when unwell. Haemagglutin...

2011-01-01

213

Antigenic characterization of phocine distemper virus causing mass mortality in 2002 and its relationship to other morbilliviruses  

British Library Electronic Table of Contents (United Kingdom)

Summary The antigenic relationship between the phocine distemper virus (PDV) strain causing the epidemic in 2002 and the PDV strain of 1988, canine distemper virus from two dogs and one marten, and one measles virus strain was investigated in vivo and in vitro using monospecific polyclonal and monoclonal antibodies directed against five different proteins of canine or phocine distemper virus (N, P, M, F, H). Epitopic mapping revealed no difference between the PDV strains causing the epidemics in 1988 or 2002. However, the use of these antibodies allowed discrimination between different morbilliviruses including a vaccine strain of canine distemper virus. The major differences among the investigated morbilliviruses were found in the H protein.

2007-01-01

214

Development of the Palliative Care Parental Self-Efficacy Measure.  

Science.gov (United States)

Caring for a child with a potentially fatal medical condition is a challenge for parents or caregivers. The ability to measure parental self-efficacy in pediatric palliative care may be an important component of targeting supportive services that address individual needs of families. Therefore, the goal was to develop a Pediatric Palliative Care Parental Self-Efficacy Measure (PCPEM). First, a list of questions were generated that asked parents their level of confidence in carrying out tasks involved in caring for a child with a potentially fatal medical condition in 6 palliative care domains: 1) medical discussion/decisions; 2) symptom management/medication; 3) daily activities; 4) feelings/concerns; 5) spirituality; and 6) end-of-life care. The PCPEM was narrowed to 58 questions after expert reviews. Then, 16 caregivers of children receiving palliative care services and 9 bereaved caregivers participated in individual focus interviews ...

2011-07-26

215

The Swedish dilemma - Nuclear energy v. the environment  

Energy Technology Data Exchange (ETDEWEB)

A phaseout of nuclear power in Sweden is supposed to be accomplished by year 2010. This study is an economic analysis of the questions that are parts of the nuclear dilemma. Even though the economic questions are in focus, the important environmental, health and safety questions are also treated. The basic argument is that Sweden should choose an energy system that allows its citizens to maximize their consumption in a long-term perspective. Consumption is here given a meaning that includes elements outside the market, such as environmental, health and safety aspects valued in a reasonable way. Considerations must also be given to international aspects like global environment, a free and open system of trade and the value of a stable set of rules and proprietary rights. The study compares the economic pros and cons of different energy systems within this general frame. A detailed model of the Swedish energy and power ...

1995-11-01

216

Hawaii technology utilization experiment  

Science.gov (United States)

A one-year technology-transfer project involving ERDA installations and Hawaii consisted of sending teams from the Lawrence Livermore Laboratory on week-long field trips every two months to test the effectiveness of different methods of transferring technology information from federal sources to civilian clients. The team was questioned primarily on non-energy matters, and the energy questions asked related mostly to individuals or small industries. The team responed to all questions and found that a wide range of knowledge was more effective than having a sequence of experts. Hawaiians considered current major ERDA projects to be irrelevant to their needs. The team was most successful on a one-to-one basis because large groups and state agencies tend to be more policy- than action-oriented. Personal followup was considered essential. The team also learned that their visits generated ten times as many inquiries as were ...

1976-12-08

217

Future Accelerators, Muon Colliders, and Neutrino Factories  

Energy Technology Data Exchange (ETDEWEB)

Particle physics is driven by five great topics. Neutrino oscillations and masses are now at the fore. The standard model with extensions to supersymmetry and a Higgs to generate mass explains much of the field. The origins of CP violation are not understood. The possibility of extra dimensions has raised tantalizing new questions. A fifth topic lurking in the background is the possibility of something totally different. Many of the questions raised by these topics require powerful new accelerators. It is not an overstatement to say that for some of the issues, the accelerator is almost the experiment. Indeed some of the questions require machines beyond our present capability. As this volume attests, there are parts of the particle physics program that have been significantly advanced without the use of accelerators such as the subject of neutrino oscillations and many aspects of the particle-cosmology interface. At this ...

2001-12-19

218

Degree of Mathematics Fluency and Success in Second-Semester Introductory Chemistry  

Science.gov (United States)

We report on the contents and results for 360 students of a mathematics assessment administered at the start of the second-semester introductory chemistry course required for science and engineering majors at the University of Minnesota. This calculator-free, 20-question, 30-minute, multiple-choice, diagnostic quiz includes questions selected specifically for their relevance to this course, concerning logarithms, scientific notation, graphs, and algebra. For the 325 students in degree-granting programs, significant correlations are reported between their mathematics assessment scores and success in this course, as measured by performance on exams (for which scientific calculators were permitted) and course grades. These observations suggest that responses to the simple questions on this unannounced quiz have some predictive utility as signatures of underlying thinking and learning patterns that are associated with success ...

2008-05-01

219

What are $E_{\\infty}$ ring spaces good for?  

CERN Document Server

Infinite loop space theory, both additive and multiplicative, arose largely from two basic motivations. One was to solve calculational questions in geometric topology. The other was to better understand algebraic K-theory. The Adams conjecture is intrinsic to the first motivation, and Quillen's proof of that led directly to his original, calculationally accessible, definition of algebraic K-theory. In turn, the infinite loop understanding of algebraic K-theory feeds back into the calculational questions in geometric topology. For example, use of infinite loop space theory leads to a method for determining the characteristic classes for topological bundles (at odd primes) in terms of the cohomology of finite groups. We explain just a little about how all that works, focusing on the central role played by E infinity ring spaces.

2009-01-01

220

Weighted shifts on directed trees  

CERN Document Server

A new class of (not necessarily bounded) operators related to (mainly infinite) directed trees is introduced and investigated. Operators in question are to be considered as a generalization of classical weighted shifts, on the one hand, and of weighted adjacency operators, on the other; they are called weighted shifts on directed trees. The basic properties of such operators, including closedness, adjoints, polar decomposition and moduli are studied. Circularity and the Fredholmness of weighted shifts on directed trees are discussed. The relationships between domains of a weighted shift on a directed tree and its adjoint are described. Hyponormality, cohyponormality, subnormality and complete hyperexpansivity of such operators are entirely characterized in terms of their weights. Related questions that arose during the study of the topic are solved as well. Particular trees with one branching vertex are intensively studied mostly in the context ...

2009-01-01

221

Understanding the mismatch between the demands of risk assessment and practice of scientists ? The case of Deca-BDE  

British Library Electronic Table of Contents (United Kingdom)

This review describes how a mismatch between the knowledge produced by scientists and the evidence demanded by regulators has emerged, and how society has struggled to find definitive answers to questions of safety, for an important flame retardant chemical in current use ? Deca-BDE. This has involved two key disciplines: analytical chemistry and toxicology. Within the chemistry, a lack of standardized methodologies among scientists has resulted in a persistent yet largely undeclared failure to replicate results within the discipline. Within the toxicology, the quest for innovative, curiosity-driven research by university scientists in preference to using validated standard protocols, designed to promote consistency within the risk assessment process, has prompted questions about the credi...

2011-01-01

222

The effect of SEM preparation on pit membrane remnants in vessel element end-walls of primitive angiosperms  

British Library Electronic Table of Contents (United Kingdom)

Scanning electron microscope (SEM) is necessary to demonstrate presence or absence of pit membranes in possible perforations or the type of pit membrane remnants in perforations in vessel element end-walls of angiosperms, but it was unconfirmed and questionable whether pit membrane absence in pits was affected by the processing and handling before SEM observations. To solve this question, the secondary xylem of four woody species from primitive angiosperms, Illicium henryi Diels. (Illiciaceae), Schisandra rubriflora (Franch.) Rehd. et Wils. (Schisandraceae), Tetracentron sinensis Oliv. and Trochodendron aralioides Sieb. & Zucc. (Trochodendraceae) was chosen and the following techniques were used: (1) fresh materials were examined in low-vacuum with ESEM. (2) Air-dried materials were examin...

2011-01-01

223

The Design and Validation of the Quantum Mechanics Conceptual Survey  

CERN Document Server

The Quantum Mechanics Conceptual Survey (QMCS) is a 12-question survey of students' conceptual understanding of quantum mechanics. It is intended to be used to measure the relative effectiveness of different instructional methods in modern physics courses. In this paper we describe the design and validation of the survey, a process that included observations of students, a review of previous literature and textbooks and syllabi, faculty and student interviews, and statistical analysis. We also discuss issues in the development of specific questions, which may be useful both for instructors who wish to use the QMCS in their classes and for researchers who wish to conduct further research of student understanding of quantum mechanics. The QMCS has been most thoroughly tested in, and is most appropriate for assessment of (as a posttest only), sophomore-level modern physics courses. We also describe testing with students in junior quantum courses ...

2010-01-01

224

Nuclear forensic investigations with a focus on plutonium  

International Nuclear Information System (INIS)

Since the beginning of the 1990s when the first seizures of nuclear material were reported, the IAEA has recorded over 200 cases of illicit trafficking of nuclear materials. Despite the decreasing frequency of nuclear material seizures, particularly the ones involving weapons-grade material, the issue continues to attract public attention and is a reason for concern due to the hazard associated with such materials. Once illicitly trafficked nuclear material has been intercepted, the questions of its intended use and origin are to be addressed. Especially the origin is of prime importance in order to close the gaps and improve the physical protection at the sites where the theft or diversion occurred. To answer these questions, a dedicated nuclear forensics methodology has been developed. In this paper an overview is given on the methodologies used, on the past and on-going developments and on the experience gathered. Some selected examples ...

2007-10-11

225

New Public Management et professions dans l'Etat : au-dela des oppositions, quelles recompositions ?  

British Library Electronic Table of Contents (United Kingdom)

More and more reforms in public administrations are being conducted that are based on the principles and instruments of ''new public management''. They have set off protest and collective actions by several professional groups in various sectors (health, education, justice, social work, research...), whence questions about the future of professional groups in public services, in particular about their autonomy, which these reforms threaten. The opposition between this new public management and certain professional groups, is not the final explanation to draw from an analysis of this situation. Should these changes be seen as the decline of professional groups and of their autonomy, as a mutation of professional models, an overhaul of professionalism, etc.? These questions, which current ev...

2011-01-01

226

Measurements of environmental policy for air pollution abatement. Umweltpolitische Massnahmen zur Luftreinhaltung; Kosten-Nutzen-Analyse  

Energy Technology Data Exchange (ETDEWEB)

The first part of the study goes into the determination of efficient strategies for the reduction of air pollutants. The developed method is not only derived theoretically but is tested with the concrete example of emissions sources of a German state. The second part goes into the question what the government can do in order to attain that air pollution abatement measures recognized as being efficient will be put into practice. As market economy mechanisms have advantages over central state planning in the allocation of economic resources the question arises if not also for environmental protection market economy tools may contribute to an improvement of the efficiency of air pollution abatement. Therefore the suitability of different tools of environmental policy for the realization of efficient air pollution abatement is investigated and evaluated. This is again not done abstractly but with existing emission sources. (orig./HSCH). 32 figs., ...

1993-01-01

227

Low-energy ion-molecule reaction dynamics and chemiionization kinetics. Progress report, February 1, 1981-January 31, 1982  

International Nuclear Information System (INIS)

This progress report concerns work completed or initiated since our last report in October of 1980. We have performed experiments in two major areas: photodissociation of organic cations to study the competition between isomerization and fragmentation; and, low energy proton transfer reactions of HCO"+ with selected neutrals. The former area provides a sideline to our combustion studies of proton transfer in hydrocarbon flames, but the question of energy transfer in highly excited gas phase ions impacts directly upon questions closely related to the fate of ions in combustion. The latter area, currently in progress, focuses upon the dynamics of biomolecular reactions of direct relevance to combustion.

228

Innovation in response to the challenges of the new energy order. The example of Predis in Grenoble  

International Nuclear Information System (INIS)

An unprecedented mobilization at all levels is being established in order to fight against the effects of climate change and announcements are increasing each week with proposals of ever more ambitious plans of action. A new landscape is beginning to take shape from a more varied energy supply with less carbon. This new order highlights several central R/D areas which are to be developed and which re described in the first part of this article. How are these plans of action going to be put into practice in the field, within the dynamics of the great unifying project 'Grenoble University of Innovation'? How can the innovation process be speeded up to quickly find answers to all these questions? How can all scientific disciplines be incorporated in this run-up and how can the different players be brought to interact? The new PREDIS centre in Grenoble, described in the second part of the article, is intended to answer these questions. (authors)

229

Hystersisters Online: Social Support and Social Comparison Among Hysterectomy Patients on the Internet  

British Library Electronic Table of Contents (United Kingdom)

Background: The Internet has become a popular source of health information for patients with a variety of medical concerns; however, research examining patient interactions on the Internet has been limited. Purpose: Four questions were examined in a survey study of hysterectomy patients who visited http://www.hystersisters.com: (a) Do hysterectomy patients use the support Web site because they perceive their proximal sources of social support to be inadequate? (b) What kinds of support do patients receive from the Web site? (c) What attributes characterize the "Hystersisters" that are perceived to be most helpful? (d) How do informational sources vary depending on the nature of the patient concern? Methods: Women (N = 137) responded to questions about social support, Web site use, and perc...

2006-01-01

230

Focus marking and focus interpretation  

British Library Electronic Table of Contents (United Kingdom)

The languages of the world exhibit a range of formal phenomena (e.g. accenting, syntactic reordering and morphological marking) that are commonly linked to the information-structural notion of focus. Crucially, there does not seem to be a one-to-one mapping between particular formal features (focus marking devices) and focus, neither from a cross-linguistic perspective, nor within individual languages. This raises the question of what is actually being expressed if we say that a constituent is focused in a particular language, and whether, or to what extent, the same semantic or pragmatic content is formally expressed by focus-marking across languages. This special issue addresses the question of focus and its grammatical realization from a number of theoretical and empirical perspectives....

2011-01-01

231

Fault location observability analysis and optimal meter placement based on voltage measurements  

British Library Electronic Table of Contents (United Kingdom)

Various transmission line fault location algorithms have been proposed in the past depending on measurements available. These methods evince that if a sufficient number of meters are placed in a power network to record the fault measurements, then the fault location can be reliably estimated. A relevant question to ask may be: how many meters are sufficient in order to derive a reliable and unique fault location estimate for a given network? This paper addresses this question by defining and performing the fault location observability analysis. An optimal meter placement scheme is proposed for determining the optimal locations to place meters so as to make the system observable while minimizing the required number of meters to reduce costs. The proposed method is especially useful for powe...

2009-01-01

232

Environmental Radiation Effects: A Need to Question Old Paradigms  

Energy Technology Data Exchange (ETDEWEB)

A historical perspective is given of the current paradigm that does not explicitly protect the environment from radiation, but instead, relies on the concept that if dose limits are set to protect humans then the environment is automatically protected as well. We summarize recent international questioning of this paradigm and briefly present three different frameworks for protecting biota that are being considered by the U.S. DOE, the Canadian government and the International Commission on Radiological Protection. We emphasize that an enhanced collaboration is required between what has traditionally been separated disciplines of radiation biology and radiation ecology if we are going to properly address the current environmental radiation problems. We then summarize results generated from an EMSP grant that allowed us to develop a Low Dose Irradiation Facility that specifically addresses effects of low-level, chronic irradiation on multiple levels of biological ...

2003-03-27

233

Educational policymaking in the Tanzanian postcolony: authenticity, accountability, and the politics of culture  

British Library Electronic Table of Contents (United Kingdom)

In this article I explore the political event of the Tanzanian government's interdiction of a prominent educational civil society organization in order to theorize the emerging policy heterarchy in Tanzania. In the context of the ensuing public debate about the interdiction, I ask two questions: (1) what tensions are emerging from the democratization reforms embedded in national iterations of international EFA policies and (2) to what end are such reforms taking place? I address these questions with ethnographic, documentary and interview data collected as part of a broader study of participation in development between 2004 and 2007 in Dar es Salaam and the Singida region of central Tanzania. My analysis draws on critical, anthropological and postcolonial theories to explore the tensions o...

2011-01-01

234

Dixon's Theorem and random synchronization  

CERN Document Server

A transformation monoid on a set Omega is called synchronizing if it contains an element of rank 1 (that is, mapping the whole of Omega to a single point). In this paper, I tackle the question: given n and k, what is the probability that the submonoid of the full transformation monoid T_n generated by k random transformations is synchronizing? This question is analogous to Dixon's Theorem that two random permutations generate the symmetric or alternating group with high probability. Following the technique of Dixon's theorem, we need to analyse the maximal non-synchronizing submonoids of T_n. I develop a very close connection between transformation monoids and graphs, from which we obtain a description of non-synchronizing monoids as endomorphism monoids of graphs satisfying some very strong conditions. However, counting such graphs, and dealing with the intersections of their endomorphism monoids, seems difficult.

2011-01-01

235

Digitization of past question papers, dissertations and theses: A case study of 30 Nigerian university libraries  

British Library Electronic Table of Contents (United Kingdom)

SummaryThis paper evaluates the status of digitization in 30 Nigerian university libraries with a view to identifying the status, progress, prospects and challenges to digitize library materials and form the basis of providing a roadmap to successful execution of digitization projects. The study assessed the status of digitization of past question papers, theses and dissertations in Nigerian university libraries from May to September 2006 through a self-administered questionnaire, site visits and interviews. It was found that, though there are automation services in those universities, there is no digitization of these materials mentioned in the surveyed institutions. The major obstacles militating against digitizing in the university libraries include lack of funds, lack of appropriate fa...

2007-01-01

236

Defining the research agenda to reduce the joint burden of disease from Diabetes mellitus and Tuberculosis  

British Library Electronic Table of Contents (United Kingdom)

Summary The steadily growing epidemic of diabetes mellitus poses a threat for global tuberculosis (TB) control. Previous studies have identified an important association between diabetes mellitus and TB. However, these studies have limitations: very few were carried out in low-income countries, with none in Africa, raising uncertainty about the strength of the diabetes mellitus-TB association in these settings, and many critical questions remain unanswered. An expert meeting was held in November 2009 to discuss where there was sufficient evidence to make firm recommendations about joint management of both diseases, to address research gaps and to develop a research agenda. Ten key research questions were identified, of which 4 were selected as high priority: (i) whether, when and how to sc...

2010-01-01

237

Computer-mediated infertility support groups: An exploratory study of online experiences  

British Library Electronic Table of Contents (United Kingdom)

Objective Over recent years the Internet has become an increasingly popular source of support and information for infertility, with a growing number of online support groups now available to individuals affected by fertility problems. The aims of the present study were therefore to explore the online experiences of individuals accessing infertility support groups via the Internet. Methods Ninety-five participants who were recruited from several online infertility support groups completed an online questionnaire containing a series of open-ended questions. Responses to the open-ended questions were analysed using inductive thematic analysis. Results The thematic analysis revealed five recurrent themes, which were labelled: `unique features of online social support', `improved relationship w...

2008-01-01

238

Communication Apprehension and Resting Alpha Range Asymmetry in the Anterior Cortex  

British Library Electronic Table of Contents (United Kingdom)

In this study, we examined the relationship between trait-like communication apprehension (CA) and resting alpha range asymmetry in the anterior cortex (AC). Although theory and research in cognitive neuroscience suggest that asymmetry in the AC constitutes a relatively stable, inborn, substrate of emotion, some studies indicate that asymmetry can be increased by experimentally induced transitory anxiety. Transitory anxiety produced by interaction with strangers covaries with trait-like CA, raising questions regarding whether asymmetrical electrical activity in the AC during data collection represents resting levels as assumed in the literature or transitory reactions to dyadic interaction with the experimenter. Because the question if unanswered poses issues for theory and approaches to r...

2011-01-01

239

Black hole and baby universe in a thin film of 3He-A  

CERN Document Server

Condensed matter black hole analogues may provide guidance in grappling with difficult questions about the role of short distance physics in the Hawking effect. These questions bear on the very existence of Hawking radiation, the correlations it may or may not carry, the nature of black hole entropy, and the possible loss of information when a black hole evaporates. We describe a model of black hole formation and evaporation and the loss of information to a disconnected universe in a thin film of 3He-A, and we explain why the existence of Hawking radiation has not yet been demonstrated in this model. [We would like this article to be accessible to researchers in both condensed matter and gravitational physics, hence we include more than the usual amount of introductory material.

2002-01-01

240

Basic environmental questions concerning lawsuits of neighboring power plant dwellers. Grundfragen umweltrechtlicher Nachbarklagen. Zum verwaltungsrechtlichen Drittschutz im Bauplanungsrecht, Immissionsschutzrecht und Kernenergierecht  

Energy Technology Data Exchange (ETDEWEB)

In conjunction with the constellation of lawsuits within the administrative court system, and based on modern environmental protection laws, emission control laws, and foremost, the atomic energy laws, we are confronted with a variety of constitutional and administrative problems. However, the fundamental questions of individual rights within the potentially incriminating environmental utilization or exploitation by individuals could be relatively clearly answered by observing the basic principles of our legal order. It is to be expected that the administrative courts will arrive at acceptable decisions reflecting the full protection of the law and the basic constitutional principles, and that these - once made - may serve as orientation in superior court actions.

1982-01-01

241

A new model of coal-water interaction and relevance for dewatering  

Energy Technology Data Exchange (ETDEWEB)

This project is concerned with a basic scientific question concerning the properties of coal--to what extent is the ability of coal to hold moisture a manifestation of the well-known ability of coal to swell, when exposed to good solvents The question implies that the long-held belief that coal holds a significant portion of its moisture by classical capillary condensation processes, is possibly in error. It is likely that a sound approach to permanent drying would involve highly crosslinking the coal at mild drying conditions. The crosslinked coal could not swell sufficiently to hold much water. It is identifying processes to achieve this goal, that constitute the objective of the second phase of this work. 25 refs., 4 figs., 1 tab.

1991-01-01

242

Rhipicephalus sanguineus: vector of a new spotted fever group rickettsia in the United States.  

Science.gov (United States)

A rickettsia related to but distinct from the spotted fever agent, Rickettsia rickettsii, has been detected in 167 (18.9%) of 884 Rhipicephalus sanguineus taken off dogs in central and northern Mississippi. The organisms could readily be isolated in male meadow voles (Microtus pennsylvanicus), where it produced massive infections in the tissues of tunica vaginalis. It was practically nonpathogenic for male guinea pigs, although inoculation of these animals with infected tunica vaginalis of voles afforded in 30 of 38 instances solid immunity to challenge with virulent R. rickettsii. The Rhipicephalus rickettsia grew well in monolayers of chicken embryo fibroblast, Vero, mouse L, and HeLa cells. Cytopathogenic effects were minimal unless large concentrations of rickettsiae were used as inocula. It also could be established in embryonated hen eggs but only after injection of massive doses of L cell-propagated organisms. Serological tests (complement fixation, microagglutination and/or ...

1975-07-01

243

Protective efficiency of dendrosomes as novel nano-sized adjuvants for DNA vaccination against birch pollen allergy  

British Library Electronic Table of Contents (United Kingdom)

We evaluated the use of a novel gene porter (Den123-a nontoxic self-assembled dendritic spheroidal nanoparticle made of biodegradable monomers), aiming to enhance and improve the desired immune response in protection from allergy. Footpad DNA immunization in Balb/c mice was done three times using the Bet v 1a gene with or without Den123 with 2-week intervals followed by sensitization with rBetv1 (5mg) in alum twice in a weekly interval. Different doses of pCMV-Betv1 were used (10mg and 100mg). The protective role of different formulations was evaluated by measuring the IgG1, IgG2a and IgE antibody production, cytokine release of isolated splenocytes and b-hexosaminidase release from the RBL cells. Higher and increasing ratios of IgG2a/IgG1 were seen in mice which received plasmids in combi...

2006-01-01

244

Investigation of xenotropic murine leukemia virus-related virus (XMRV) in human and other cell lines.  

Science.gov (United States)

Xenotropic murine leukemia virus-related virus (XMRV) was discovered in human prostate tumors and later in some chronic fatigue syndrome (CFS) patients. However, subsequent studies have identified various sources of potential contamination with XMRV and other murine leukemia virus (MLV)-related sequences in test samples. Biological and nucleotide sequence analysis indicates that XMRV is distinct from known xenotropic MLVs and has a broad host range and cell tropism including human cells. Therefore, it is prudent to minimize the risk of human exposure to infection by evaluating XMRV contamination in cell lines handled in laboratory research and particularly those used in the manufacture of biological products. Nested DNA PCR assays were optimized for investigating XMRV gag and env sequences in various cell lines, which included MRC-5, Vero, HEK-293, MDCK, HeLa, and A549, that may be used in the development of some vaccines and other cell lines broadly used in ...

2011-10-11

245

Hepatitis B immunization coverage and risk behaviour among Danish travellers Are immunization strategies based on single journey itineraries rational?  

DEFF Research Database (Denmark)

OBJECTIVES: The authors examine the rationale and efficacy of pre-travel hepatitis B immunization strategies based on itinerary and presumed on-travel risk behaviour. METHODS: A large survey among 26,640 Danes survey provided data on journey lengths and destinations, immunization coverage, risk behaviour and knowledge. RESULTS: The estimated cumulative lifetime stay in endemic areas outside Europe is 4.3 months. The majority of risk situations are involuntary and unforeseeable. The majority of risk situations occur on short-term journeys. 5% nonimmune and 5% short-term travellers experienced at least one risk situation such as injections/operations/tattoos on their journey. The level of knowledge of hepatitis A and B is low. CONCLUSIONS: The rationale and efficacy of current immunization strategies are challenged. Based on the results presented here and the availability of vaccines with long-lasting coverage, the authors find that recommendations of immunization ...

2009-01-01

246

GAMMA GLOBULIN METABOLISM IN RABBITS DURING THE ANAMNESTIC RESPONSE.  

Science.gov (United States)

1. Gamma globulin metabolism and distribution were studied employing rabbit gamma globulin (RGG)I(131) 24 times in 13 control rabbits. Similar studies were performed before and during the ananmestic response in 4 rabbits previously sensitized with a polyvalent pneumococcal vaccine. 2. During the ananmestic response, gamma-globulin levels increased from 1.0 to 6.0 gm/100 ml, and the gamma-globulin pool increased from 0.7 to 4.7 gm/kg. There was no change in the intravascular-extravascular partition of gamma globulin. 3. Gamma globulin degradation increased from 0.06 to 0.33 gm/kg/day during the 28 days of the immunization period while gamma globulin synthesis increased even further to average 0.47 gm/kg/day. Following the attainment of elevated gamma globulin levels the fractional rate of RGG-I(131) turnover increased from 8.0 to 12.5 per cent/day. 4. No differences were noted in the metabolism of homologous or autologous gamma globulin regardless of the allotypic ...

1964-04-01

247

Concise review: expanding roles for hematopoietic cellular therapy and the blood transfusion services.  

Science.gov (United States)

Hematopoietic stem cells (HSCs) have remained at the forefront of stem cell research for the past 50 years, since the therapeutic potential of bone marrow transplantation was realized. Uniquely, among stem and progenitor cells, research progress has been made in parallel between the laboratory benchtop and hospital bedside during this period. Integral to this work has been the role of the transfusion medicine services in the collection, storage, and processing of HSCs. The next decade promises to bring further developments: with new fields of cellular therapies, stem cell vaccination, and stem cell drug testing opening up. This article summarizes exciting areas of research concerning the behavior and potential clinical applications of HSCs. For the purposes of clarity, we describe in turn the trafficking and transfer of HSCs; ex vivo expansion of HSC units from different sources; and finally, applications of specifically selected subsets of hematopoietic cells and ...

2011-09-01

248

Biotechnology developments in the livestock sector in developing countries.  

Science.gov (United States)

Global meat and milk consumption is exponentially increasing due to population growth, urbanization and changes in lifestyle in the developing world. This is an excellent opportunity for developing countries to improve the livestock sector by using technological advances. Biotechnology is one of the avenues for improved production in the "Livestock revolution". Biotechnology developments applied to livestock health, nutrition, breeding and reproduction are improving with a reasonable pace in developing countries. Simple bio-techniques such as artificial insemination have been well implemented in many parts of the developing world. However, advanced technologies including transgenic plant vaccines, marker assisted selection, solid state fermentation for the production of fibrolytic enzymes, transgenic fodders, embryo transfer and animal cloning are confined largely to research organizations. Some developing countries such as Taiwan, China and Brazil have considered ...

2010-01-01

249

An adjuvant autologous therapeutic vaccine (HSPPC-96; vitespen) versus observation alone for patients at high risk of recurrence after nephrectomy for renal cell carcinoma: a multicentre, open-label, randomised phase III trial  

British Library Electronic Table of Contents (United Kingdom)

Summary Background Treatment of localised renal cell carcinoma consists of partial or radical nephrectomy. A substantial proportion of patients are at risk for recurrence because no effective adjuvant therapy exists. We investigated the use of an autologous, tumour-derived heat-shock protein (glycoprotein 96)-peptide complex (HSPPC-96; vitespen) as adjuvant treatment in patients at high risk of recurrence after resection of locally advanced renal cell carcinoma. Methods In this open-label trial, patients were randomly assigned to receive either vitespen (n=409) or observation alone (n=409) after nephrectomy. Randomisation was done in a one to one ratio by a computer-generated pseudo-random number generator, with a block size of four, and was stratified by performance score, lymph node stat...

2008-01-01

250

Wind tunnel modeling of heat islands in a turbulent boundary layer  

International Nuclear Information System (INIS)

The basic studies of this report, had been done with a wind tunnel. Model similarity with typical atmospheric situations - such as an urban heat island - had to exist. Sufficient heat is needed to generate turbulent convection at the ground. By omitting the Boussinesq-approximation proper similarity parameters could be found to present the results in a dimensionless form. Also the effect of a cross circulation was investigated as well as the question at which conditions the convection is no longer able to overcome the longitudinal momentum of the wind. (KW).

251

Why CCR2 and CCR5 Blockade Failed and Why CCR1 Blockade Might Still Be Effective in the Treatment of Rheumatoid Arthritis  

UK PubMed Central (United Kingdom)

BackgroundThe aim of this study was to provide more insight into the question as to why blockade of CCR1, CCR2, and CCR5 may have failed in clinical trials in rheumatoid arthritis...Full Text Available

252

Volcano Field Trip  

Science.gov (United States)

This site focuses on the subject of volcanoes, including how volcanoes form, the destruction they can cause, effects of volcanoes on the environment, where active volcanoes are found, volcanoes of other planets, and the different volcano types. Designed as an electronic tour, it guides the user through different web sites and outlines teaching objectives, concepts covered, and new vocabulary. There is a teacher resources section with links for more information, and questions for students to answer along the way.

253

Use of endobronchial one-way valves reveals questions on etiology of spontaneous pneumothorax: report of three cases  

UK PubMed Central (United Kingdom)

Spontaneous pneumothoraces are believed to arise when air from the supplying airway exit via a ruptured visceral pleural bleb into the pleural cavity. Endobronchial one-way valves (EBVs) allow air exit...Full Text Available

254

Unfolding of differential energy spectra in the MAGIC experiment  

Energy Technology Data Exchange (ETDEWEB)

The paper describes the different methods, used in the MAGIC experiment, to unfold experimental energy distributions of cosmic ray particles ({gamma}-rays). Questions and problems related to the unfolding are discussed. Various procedures are proposed which can help to make the unfolding robust and reliable. The different methods and procedures are implemented in the MAGIC software and are used in most of the analyses.

2007-12-21

255

Unambiguous 1-Uniform Morphisms  

CERN Document Server

A morphism h is unambiguous with respect to a word w if there is no other morphism g that maps w to the same image as h. In the present paper we study the question of whether, for any given word, there exists an unambiguous 1-uniform morphism, i.e., a morphism that maps every letter in the word to an image of length 1.

2011-01-01

256

Transitional nuclei and triaxial shapes  

International Nuclear Information System (INIS)

Evidence for triaxial nuclear shapes from families of unique-parity states in transitional odd-A nuclei around mass A=190 and A=130 is reviewed. The experimental data are analysed within the odd-A triaxial core model. Regular two-dimensional band patterns are found in experiment and are shown to be a consequence of broken axial symmetry. Recent theoretical developments are discussed including the question of how stable the triaxial shapes are.

257

The feasibility of closing the loop  

Energy Technology Data Exchange (ETDEWEB)

Current European and the US experiences in waste management are reviewed in the perspective of sustainable development. This publication questions the validity of the current approach taken by the Germany at ``closing the loop`` based on the example of packaging and packaging waste. The product item focus of current German legislation is compared with Danish and US approaches that are based on an integrated policy which covers the whole of waste generation and handling and is not product/item oriented. 1 fig., 2 tabs.

1998-12-01

258

Target space duality II: applications  

Energy Technology Data Exchange (ETDEWEB)

We apply the framework developed in Target space duality I: general theory. We show that both nonabelian duality and Poisson-Lie duality are examples of the general theory. We propose how the formalism leads to a systematic study of duality by studying few scenarios that lead to open questions in the theory of Lie algebras. We present evidence that there are probably new examples of irreducible target space duality.

2000-09-25

259

Synfuels: how much can they help. [Chevron activities  

Science.gov (United States)

A series of questions and answers addresses issues related to developing synthetic fuels, including the potential supplies, regulatory road blocks, and development incentives to promote the role of the private sector. Chevron's efforts in the area of synfuels are aimed at shale oil tar sands and coal conversion. The status of these research and development projects and the projected recoverable reserves from each are summarized. (DCK)

260

Swedish Ceramic Institute  

Science.gov (United States)

The Swedish Ceramic Institute is an industrial research institute working with product-oriented research and development of ceramics and closely related materials. The institute works with the processing and fabrication of ceramic materials as well as with materials properties and design questions. Its website provides details of research projects (engineering ceramics, electroceramics, traditional ceramics). Publications are listed, with some downloadable files (annual reports, research reports, information leaflets). Sample materials data (mechanical properties, thermal properties) is given for oxides and non-oxide ceramics.

2007-02-01

261

Supersymmetry. Present status and prospects  

Energy Technology Data Exchange (ETDEWEB)

Starting from the gauge hierarchy problem as a motivation, supersymmetric theories are reviewed. The minimal supersymmetric standard model is briefly described and the possible soft breaking terms of supersymmetry are introduced. Phenomenological questions are addressed for the flavor changing neutral current and CP violation. Phenomenological evidences for the supersymmetric grand unified models are reviewed and proton decay is examined. Relations with supergravity and superstring unification is also mentioned. (author).

1995-05-01

262

Spent fuel waste disposal: analyses of model uncertainty in the MICADO project  

International Nuclear Information System (INIS)

The objective was to find out whether international research has now provided sufficiently reliable models to assess the corrosion behavior of spent fuel in groundwater and by this to contribute to answering the question whether the highly radioactive used fuel from nuclear reactors can be disposed of safely in a geological repository. Principal project results are described in the paper

2010-10-01

263

Scaling properties of cell and organelle size  

UK PubMed Central (United Kingdom)

How size is controlled is a fundamental question in biology. In this review, we discuss the use of scaling relationships—for example, power-laws of the form y∝xα—to...Full Text Available

2010-04-01

264

SM Higgs properties measurement at ATLAS  

CERN Document Server

The discovery of a new particle in the Higgs searches being prepared for LHC will not guarantee that the Standard Model Higgs boson has been seen. This paper discusses the possibilities for measuring the spin, parity and couplings of the particle, under the assumption that it does in fact behave like the Standard Model Higgs. The key question, which cannot alas be answered, is: if it looks like a dog, and barks like a dog, how much of the DNA must we analyse to be sure that it is a dog?

2009-01-01

265

Risk-orientated analysis of the SNR 300. Technical report 1  

International Nuclear Information System (INIS)

The study required by the West German Ministry of Research and Technology (RS 605) for the Committee on 'Future Nuclear Energy Policy' of the 9th German Parliament is concerned with the following main points: 1) Assessment of technical risks from the social aspect; 2) Discussion of terms and quantification of risks; 3) 'Engineering judgment' and 'questionable' methods in the Fast Breeder analysis of the Society for Reactor Safety (GRS); 4) Assessment criteria of potential damage. (HP).

266

Replication, Pathogenesis and Transmission of Pandemic (H1N1) 2009 Virus in Non-Immune Pigs  

UK PubMed Central (United Kingdom)

The declaration of the human influenza A pandemic (H1N1) 2009 (H1N1/09) raised important questions, including origin and host range [1],...Full Text Available

267

Public hearings on water management in Quebec: First Nations and water resources -- Supporting documentation for the Commission Workshop at Mashteuiatsh, Aug 18, 1999; Consultation publique sur la gestion de l'eau au Quebec: Les premieres nations et la ressource eau -- Document de soutien a atelier de travail de la Commission du 18 aout 1999 a Masteuiatsh  

Energy Technology Data Exchange (ETDEWEB)

Since mid-March the Commission on Water Management, with the assistance of the appropriate ministries, visited all regions of the province in order to acquaint themselves first hand with regional water management problems. During the month of June, the Commission also organized a series of ten workshops, attended by a limited number of experts, to explore in depth certain specific questions in the area of water management. During these public sessions the Commission hoped to discuss specifically the specific questions relating to water management problems of First Nations communities, bearing in mind the essential nature of water in maintaining traditional activities. The workshop took place on the Montanard reserve of Mashteuiatsh (Pointe-Bleu). The morning session was devoted to presentations by invited experts, followed by an exchange of views between the experts and the Commissioners, with opportunity for participants to address ...

1999-08-13

268

Pitting corrosion  

International Nuclear Information System (INIS)

Pitting corrosion is a kind of electrolytic corrosion by which the surface of a material is locally affected owing to inhomogeneities on the part of the material or medium. The paper deals briefly with questions relating to the importance, to parameters medium or materialwise, influence on production and construction, as well as the general conditions for pitting corrosion. In particular oxygen corrosion in unalloyed and low-alloy steel, and pitting corrosion in ferritic chromium-steel and austenitic chromium-nickel (molybdenum) steel is described. (DG).

269

Organization of setting-up sanitary pass-control regime and sanitary treatment of injured persons in case of radiation accidents  

International Nuclear Information System (INIS)

The main aim of sanitary pass-control regime is to prevent propagation of radioactive contamination outside the area of emergency-rescue works and guarantee of sanitary treatment of all persons having radioactive contamination. The paper has studied the questions of organization of sanitary pass-control regime, arrangement of sanitary treatment of the injured persons and rendering first aid in case of radioactive contamination of wounds. 5 refs.

270

On the CSFT approach to localized closed string tachyons  

Energy Technology Data Exchange (ETDEWEB)

We compute the potential for localized closed string tachyons in bosonic string theory on the orbifold C/Z{sub 4} using level-truncated closed string field theory. The critical points of the potential exhibit features which agree with their conjectured identification as lower-order orbifolds. However this case also raises some questions regarding the quantitative predictions associated with these conjectures. (author)

2005-01-01

271

Nuclear magnetic resonance and the question of 5f electron localization in the actinides  

International Nuclear Information System (INIS)

Nuclear magnetic resonance results are presented for a number of NaCl-type compounds and cubic Laves-phase type compounds of uranium, neptunium, and plutonium. Special emphasis is placed on the Knight shift and spin-lattice relaxation time measurements and their interpretation in terms of localized or itinerant pictures of the 5f electrons. (author).

272

Nuclear magnetic resonance and the question of 5F electron localization in the actinides  

Science.gov (United States)

Nuclear magnetic resonance results are presented for a number of NaCl-type compounds and cubic Laves-phase type compounds of uranium, neptunium, and plutonium. Special emphasis is placed on the Knight shift and spin-lattice relaxation time measurements and their interpretation in terms of localized or itinerant pictures of the 5Line integral electrons.

1976-01-01

273

Nuclear forensics in law enforcement applications  

International Nuclear Information System (INIS)

Over the past several years, the Livermore Forensic Science Center has conducted analyses of nuclear-related samples in conjunction with domestic and international criminal investigations. Law enforcement officials have sought conventional and nuclear-forensic analyses of questioned specimens that have typically consisted of miscellaneous metal species or actinide salts. The investigated activities have included nuclear smuggling and the proliferation of alleged fissionable materials, nonradioactive hoaxes such as 'Red Mercury', and the interdiction of illegal laboratories engaged in methamphetamine synthesis. (author)

1998-09-01

274

Mechanism of radiation induced carcinogenesis: does a threshold exist?  

International Nuclear Information System (INIS)

Epidemiological studies will not solve the shape of the dose effect curve for stochastic effects in the low dose range. Unicellular processes are necessary for the primary processes so that no threshold dose exists. This is evident for somatic and genetic mutations. Not clearly solved is this question for the complex carcinogenesis. These processes develop with manifold interacting molecular and cellular steps. (orig.).

1996-10-23

275

Maximum overhang  

CERN Document Server

How far can a stack of $n$ identical blocks be made to hang over the edge of a table? The question dates back to at least the middle of the 19th century and the answer to it was widely believed to be of order $\\log n$. Recently, Paterson and Zwick constructed $n$-block stacks with overhangs of order $n^{1/3}$, exponentially better than previously thought possible. We show here that order $n^{1/3}$ is indeed best possible, resolving the long-standing overhang problem up to a constant factor.

2007-01-01

276

Mathematical analysis of the length-of-arc assumption  

Energy Technology Data Exchange (ETDEWEB)

The observation by Maday in 1974 that the Schmidt-Duffin solution to the optimal fin profile problem was flawed due to neglect of the slant height factor led to a new solution--actually, a demonstration of the ill-posedness of the question--by Snider. The present article proves mathematically that omission of this factor leads inevitably to underestimation of the heat transfer capability of any fin. Additionally, a perturbation scheme for estimating the correction for this effect is derived for configurations with low generalized Biot numbers, and a revised assessment of the performance of the Schmidt fin is presented.

1996-04-01

277

Major steam turbine losses. Causes, repair measures, recommissioning; Grossschaeden an Dampfturbosaetzen. Ursachen, Reparaturen, Weiterbetrieb  

Energy Technology Data Exchange (ETDEWEB)

Substantial damages at main components of steam turbines do not have to result inevitably in an exchange of the components concerned. Rather a preliminary or final repair is possible which also considers the cause of the damage. An important condition with the technically complex questions is an appropriate qualification and experience of all involved persons. The common task of operators, manufacturers and insurance companies is to preserve the balance from costs, expenditure of time and risk.

2010-07-01

278

Main concepts of modern methods for substantiating extractable reserves and coefficients of oil extraction from the depths  

Energy Technology Data Exchange (ETDEWEB)

General conclusions, principles and order of substantiating the extractable reserves and coefficients of oil extraction from oil and oil and gas fields are presented. Recommendations are made for solving questions of constructing calculation models for heterogeneous beds, schematization of the working conditions, selection of mathematical models for oil extraction for different geological-field conditions and different stages of ''life'' of the field.

1984-01-01

279

Lithium question for nuclear fusion  

International Nuclear Information System (INIS)

An attempt is made to estimate the lithium reserve (the economically recoverable lithium) for the tritium breeding in D-T fusion reactors and other uses. Similar development patterns for fusion energy and fission energy are assumed to estimate the future lithium requirements. These requirements are grouped into three categories; the commercial uses, the lithium batteries for electric cars, and the fusion reactor uses. 5 refs.

280

Isotope Production at the Hanford Site in Richland, Washington  

Energy Technology Data Exchange (ETDEWEB)

This report was prepared in response to a request from the Nuclear Energy Research Advisory Committee (NERAC) subcommittee on ''Long-Term Isotope Research and Production Plans.'' The NERAC subcommittee has asked for a reply to a number of questions regarding (1) ''How well does the Department of Energy (DOE) infrastructure sme the need for commercial and medical isotopes?'' and (2) ''What should be the long-term role of the federal government in providing commercial and medical isotopes?' Our report addresses the questions raised by the NERAC subcommittee, and especially the 10 issues that were raised under the first of the above questions (see Appendix). These issues are related to the isotope products offered by the DOE Isotope Production Sites, the capabilities and condition of the facilities used to produce these products, ...

1999-06-01

281

Identification of a nuclear-localized nuclease from wheat cells undergoing programmed cell death that is able to trigger DNA fragmentation and apoptotic morphology on nuclei from human cells  

UK PubMed Central (United Kingdom)

PCD (programmed cell death) in plants presents important morphological and biochemical differences compared with apoptosis in animal cells. This raises the question of whether PCD arose independently...Full Text Available

2006-08-01

282

Global quantum gauge symmetry via reconstruction theorems  

Energy Technology Data Exchange (ETDEWEB)

In this paper we establish that every quantum field theory satisfying some basic axioms possesses a weak quasi Hopf algebra as gauge symmetry. We use a reconstruction theorem to find this symmetry algebra and show how it is sed to build a gauge covariant field algebra. We investigate the question of why this generality is necessary. The non-uniqueness of the reconstruction process is interpreted and a cohomological classification of possible global gauge symmetries is given. (author)

1996-12-21

283

Gamma ray observations of the solar system  

Energy Technology Data Exchange (ETDEWEB)

Two general categories are discussed concerning the evolution of the solar system: the dualistic view, the planetesimal approach and the monistic view, the nebular hypothesis. The major points of each view are given and the models that are developed from these views are described. Possible applications of gamma ray astronomical observations to the question of the dynamic evolution of the solar system are discussed.

1981-01-01

284

Finding the best quadratic approximation of a function  

British Library Electronic Table of Contents (United Kingdom)

This article examines the question of finding the best quadratic function to approximate a given function on an interval. The prototypical function considered is f(x) = ex. Two approaches are considered, one based on Taylor polynomial approximations at various points in the interval under consideration, the other based on the fact that three non-collinear points determine a unique quadratic function. Three different techniques for measuring the error in the approximations are considered.

2011-01-01

285

Experts' discussion on the possibility of quantification of the radiation hazard  

International Nuclear Information System (INIS)

Due to the intensity and vast number of subjects, this Bremen experts' discussion, too, could discuss only part of the problem of the possibilitiy to quantify the radiation hazard. One preliminary result is that there is no scientific proof of the harmlessness of radiation exposure during normal operation of a nuclear power plant, either within the plant or in its vicinity. Other results are that some important questions can not be answered yet, and that there are important hints on the dangers even of low radiation doses. (GL).

1978-01-01

286

Expanding the role of the cost engineer  

Energy Technology Data Exchange (ETDEWEB)

There have been many questions about the costs of providing medical services. These questions have resulted in the development of Resource-Based Relative Values Scale (RBRVS) at the national level. Policymakers view RBRVS as a potential tool to pay physicians. The questions, about the cost of operations of HSE-2 at Los Alamos National Laboratory, revolve around doing routine occupation health physicals for the Laboratory. Generally, these questions are concerned about why the costs appear to be high relative to what private physician suggests the costs should be. There is also an interest in trying to find methods to reduce these costs if possible. Many of the tools developed to help in construction estimating can be applied to estimating medical costs. With the need to perform many thousands of physicals each year the saving of even a few dollars for each exam can quickly add up to a large saving. ...

1989-01-01

287

Economic effects on taxing CO{sub 2} emissions  

Energy Technology Data Exchange (ETDEWEB)

The CO{sub 2} emissions can be reduced by using economic instruments, like carbon tax. This project included two specific questions related to CO{sub 2} taxation. First one was the economic effects of increasing CO{sub 2} tax and decreasing other taxes. Second was the economic adjustment costs of reducing net emissions instead of gross emissions. A computable general equilibrium (CGE) model was used in this analysis. The study was taken place in Helsinki School of Economics

1996-12-31

288

Ecobalance of thermoplastic materials. El balance medioambiental de los productos termoplasticos  

Energy Technology Data Exchange (ETDEWEB)

The creation of a methodology about the Ecobalance of the main plastic materials manufactured in Europe is very helpful for many questions relating with these matters. This methodology is necessary for the EC and most of its members. It is important that these analysis have available, precise and up-to-date information. In order that these dates are well-known, the european industry of plastics recognised and started an ambitious project two years ago and now we can see the first results.

1994-01-01

289

Direct conversion of fusion energy into the electric one in the 'Dragon' magnetic confinement system  

International Nuclear Information System (INIS)

It is shown that recuperator in which the thermal energy of particles is transformed into electric oue under drift in crossed fields is naturally coupled with dragontype magnetic confinement system, so the recuperation process can be initiated in the dragon magnetic field. A number of questions occuring under analysis of recuperator-dragon system is considered, including the dynamics of particle transfer to the recuperator, the share of particles entering the recuperator, the effect of rotational transform and the recuperation efficiency.

290

Detonation of explosives  

Energy Technology Data Exchange (ETDEWEB)

In recent years new, less-sensitive explosives have been developed together with new types of detonator. Four sections are covered: 1) Description of various developments achieved by the laboratories of Nobel Explosifs over the past 12 years; 2) Explanation of the limits of application of the various products; 3) Thoughts on the various detonator systems and their effectiveness; and 4) Advice and recommendations for the use of the new product range. The products in question are : dynamites, nitrates, oil nitrates, gels and slurry explosives. (17 refs.)

1983-04-01

291

Determining the boundary between underground and open pit mining at the deposits of the Far North  

Energy Technology Data Exchange (ETDEWEB)

The question about expanding the boundaries of the open pit mining method is examined. The use of methods which consider the advantages of open and underground mining operations with their joint use in horizontal and evenly dipping deposits will make it possible to objectively select the mining method, to expand the range of use of open pit mining operations in the deposits of the Far North and provide an improvement in the technical and economic indicators of mineral extraction.

1984-01-01

292

Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression  

UK PubMed Central (United Kingdom)

Metastatic disease is a primary cause of cancer-related death, and factors governing tumor cell metastasis have not been fully elucidated. Here, we address this question by using tumor cell lines derived...Full Text Available

2009-09-15

293

Comments on possible preferential order-disorder in A-15 compounds based upon Nb  

International Nuclear Information System (INIS)

The possible existence of preferential B-site disorder in A-15 compounds recently claimed on the basis of x-ray powder diffraction data but questioned from the viewpoint of known phase diagrams is examined for some Nb-based compounds of this type. It is concluded that x-ray powder data do not allow the determination of both order and compositional variables as suggested, and the latter must therefore be determined by some other method. (author).

294

CCNA Cisco Certified Network Associate Study Guide: Exam 640-801  

CERN Document Server

Here's the book you need to prepare for Cisco's revised CCNA exam, 640-801. This new edition of the best-selling CCNA Study Guide provides in-depth coverage of every CCNA exam objective, practical information on Cisco internetworking solutions and hundreds of challenging review questions.

2006-01-01

295

Biological effects of extremely low frequency (ELF) electromagnetic fields: a perspective on the issues  

Energy Technology Data Exchange (ETDEWEB)

This apper discusses whether health risks are associated with exposure to electromagnetic fields that exist beneath high-voltage transmission lines. This is a question receiving increasing attention as the electric utility industry prepares to supply its customers with increased amounts of electric power. 26 refs.

1980-01-01

296

Beyond Boomer Meets NextGen: Examining Mentoring Practices among Pennsylvania Academic Librarians  

British Library Electronic Table of Contents (United Kingdom)

A survey to assess mentoring experiences and attitudes towards work of Pennsylvania academic librarians was conducted in September 2006 with questions concerning mentoring experiences, work experiences, and attitudes towards work. Results of the survey are analyzed for differences among those librarians responding, especially generational differences, and implications for professional associations when developing mentoring programs are discussed.

2011-01-01

297

Aspen Winter Conference Series  

Science.gov (United States)

(B204) The meeting will bring together observers and theorists in a highly interactive format, to further connect the local and cosmological star formation communities. Forward looking talks, aimed at the other communities, will survey terminology, achievements, problems and aspirations. Discussion will focus on the definition of the key questions, how the different communities can help each other, and preparations for the incorporation of realistic star formation into cosmological simulations.

1999-01-01

298

A note on the axioms for Zilber's pseudo-exponential fields  

CERN Document Server

We show that Zilber's conjecture that complex exponentiation is isomorphic to his pseudo-exponentiation follows from the a priori simpler conjecture that they are elementarily equivalent. We also show that the class of all pseudo-exponential fields is an example of a non-finitary abstract elementary class, answering a question of Kes\\"al\\"a and Baldwin.

2010-01-01

299

On the Role of Convection and Turbulence for Tropospheric Ozone and its Precursors  

International Nuclear Information System (INIS)

The aim of the work in this thesis is to investigate the convective and diffusive transport in the TM chemistry transport model, and to investigate some aspects of the consequences for NOx. The large inaccuracy and uncertainty in the description of processes like convection and turbulent diffusion, the strong dependence of the radiative forcing of ozone on its vertical distribution, and the strong dependence of the ozone production on the distribution of NOx, are the main motivation. The availability of the ERA-40 data, where convective data and vertical diffusion coefficients are archived, allows a study of the effect of different convective mass flux sets, and different vertical diffusion coefficients on the model-simulated distribution of tracers. In this thesis the following questions are addressed : (1) How large is the sensitivity of the (model simulated) distribution of ozone and nitrogen oxides on (the) convection (parameterisation)?; (2) What requirements ...

300

Valuing climate protection through willingness to pay for biomass ethanol  

Energy Technology Data Exchange (ETDEWEB)

This study uses a multi-part, split-sample contingent valuation method (CVM) and fair share (FS) survey to better understand the public's valuation of mitigating global climate change through its willingness to pay for biomass or 'cellulosic' ethanol. In addition to a basic CVM question, a related scenario was developed that asked half of the survey respondents to state their fair share cost to lessen a potential food shortage in the next decade, also through the expanded use of cellulosic ethanol. Three alternative biomass feedstocks were assessed: farming residues, forestry residues and paper mill wastes, and municipal solid wastes. Overall a slightly larger proportion of respondents were WTP extra for cellulosic ethanol in the basic CVM scenario than in the FS scenario, though no significant differences were found in the WTP for the different feedstocks. Bid curve lognormal regression results for the two models were similar, supporting ...

2009-05-15

301

Self-assessment of current knowledge in nuclear medicine (second edition)  

Energy Technology Data Exchange (ETDEWEB)

In this updated second edition, the order of contents of the textbook has been reorganized. It has been divided into main parts: Basic Science and Clinical Nuclear Medicine. Basic Science, Part I, encompasses basic physics, radiation protection, interaction of radiation with matter and radiation detection, imaging, nuclear pharmacy, and radiation biology. Part II, Clinical Nuclear Medicine, covers the central nervous system, bone, gastroenterology (liver/spleen), cardiovascular system, pulmonary system, genitourinary system, thyroid and endocrine systems, gallium studies, radioassay, hematology, and therapy. The total number of pages of the current edition is increased to 250 from the 213 of the first edition but there are fewer questions because those in the basic science area have been carefully selected to 60 of the original 98 questions. Compared with the previous edition, there are two advantages in the current one: (1) the addition of ...

1981-01-01

302

Review of the study and application on nuclear forensic analysis  

International Nuclear Information System (INIS)

For the interests of national security, many scientists who work in the field of nuclear forensic analysis have carried out extensive work in the past on the detection of radioactive material and attributions study, developed a series of scientific and technical means to trace and detect illicit circulation of nuclear materials used to weapons and other radioactive materials which impair public security. All these questions relate to physical, chemical, biological attribution of materials. The nuclear forensic analysis has already become a special, up-to-date sphere of learning. The goal of the study of nuclear forensics is to prevent terrorists from acquiring not only nuclear weapons but also mate- rials that can be used to make such weapons, including radioactive materials for nuclear power plants, and medical radioisotope to and provide us as many clues of environmental links as possible that could help us trace the smuggling path, to answer the following ...

2009-12-01

303

Quantum frustration in organic Mott insulators: from spin liquids to unconventional superconductors  

CERN Document Server

We review the interplay of frustration and strong electronic correlations in quasi-two-dimensional organic charge transfer salts, such as k-(BEDT-TTF)_2X and Et_nMe_{4-n}Pn[Pd(dmit)2]2. These two forces drive a range of exotic phases including spin liquids, valence bond crystals, pseudogapped metals, and unconventional superconductivity. Of particular interest is that in several materials there is a direct transition as a function of pressure from a spin liquid Mott insulating state to a superconducting state. Experiments on these materials raise a number of profound questions about the quantum behaviour of frustrated systems, particularly the intimate connection between spin liquids and superconductivity. Insights into these questions have come from a wide range of theoretical techniques including first principles electronic structure, quantum many-body theory and quantum field theory. In this review we introduce the basic ideas of the field ...

2010-01-01

304

Population exposure to power-frequency fields: concepts, components, and control  

Energy Technology Data Exchange (ETDEWEB)

There are many sources of population exposures to power-frequency (50/60 Hz) electric and magnetic fields including household appliances and wiring, neighborhood distribution circuits, and high-voltage transmission lines. Bioeffects studies were unable to demonstrate that exposures to power-frequency fields can affect public health. Researcher have likewise been unable to show that the health effects of such exposures are negligible. State and federal regulatory agencies are, therefore, grappling with questions of whether and how to regulate the sitting or design of new extra high-voltage transmission lines so as to control the ground-level fields to which people are exposed. The purpose of this dissertation is to illuminate some of the exposure-related aspects of these question. A taxonomy of the relationship between field encounter and effect is developed to clarify the meaning of terms such as exposure and dose in the power-frequency ...

1986-01-01

305

Photovoltaic industry manufacturing technology. Final report  

Energy Technology Data Exchange (ETDEWEB)

This report contains the results of the Photovoltaic (PV) Industry Manufacturing Technology Assessment performed by the Automation and Robotics Research Institute (ARRI) of the University of Texas at Arlington for the National Renewable Energy laboratory. ARRI surveyed eleven companies to determine their state-of-manufacturing in the areas of engineering design, operations management, manufacturing technology, equipment maintenance, quality management, and plant conditions. Interviews with company personnel and plant tours at each of the facilities were conducted and the information compiled. The report is divided into two main segments. The first part of the report presents how the industry as a whole conforms to ``World Class`` manufacturing practices. Conclusions are drawn from the results of a survey as to the areas that the PV industry can improve on to become more competitive in the industry and World Class. Appendix A contains the questions asked in the ...

1998-08-01

306

Organization of bulk power markets: A concept paper  

Energy Technology Data Exchange (ETDEWEB)

The electricity industry in the US today is at a crossroads. The restructuring debate going on in most regions has made it clear that the traditional model of vertically integrated firms serving defined franchise areas and regulated by state commissions may not be the pattern for the future. The demands of large customers seeking direct access to power markets, the entry of new participants, and proposed reforms of the regulatory process all signify a momentum for fundamental change in the organization of the industry. This paper addresses electricity restructuring from the perspective of bulk power markets. The authors focus attention on the organization of electricity trade and the various ways it has been and might be conducted. Their approach concentrates on conceptual models and empirical case studies, not on specific proposals made by particular utilities or commissions. They review literature in economics and power system engineering that is relevant to the major ...

1995-12-01

307

Ly-alpha emitters: blue dwarfs or supermassive ULIRGs? Evidence for a transition with redshift  

CERN Document Server

The traditional view that Ly-alpha emission and dust should be mutually exclusive has been questioned more and more often, notably the observations of Ly-alpha emission from ULIRGs seems to counter this view. In this paper we seek to address the reverse question: How large a fraction of Ly-alpha selected galaxies are ULIRGs? Using two samples of 24/25 Ly-alpha emitting galaxies at z = 0.3/2.3 we perform this test, also including results at z = 3.1, and find that whereas the ULIRG fraction at z = 3.1 is very small, it systematically increases towards lower redshifts. There is a hint that this evolution may be quite sudden and that it happens around a redshift of z ~ 2.5. Measuring the infrared luminosities of the Ly-alpha emitters, we find that they are in the normal to ULIRG range in the lower redshift sample, whereas the higher redshift galaxies all have luminosities in the ULIRG category. The Ly-alpha escape fractions for these infrared ...

2009-01-01

308

Increase in the number of distributed power generation installations in electricity distribution grids - Project findings; Zunahme der dezentralen Energieerzeugungsanlagen in elektrischen Verteilnetzen: Erkenntnisse aus dem Projekt  

Energy Technology Data Exchange (ETDEWEB)

This is the eighth part of a ten-part final report for the Swiss Federal Office of Energy (SFOE) on a project that looked into potential problems relating to the Swiss electricity distribution grid with respect to the increasing number of distributed power generation facilities being put into service. The identification of special conditions for the grid's operation and future development that take increasing decentralised power production into account are discussed. The results of the project activities encompass the analysis and evaluation of various problem areas associated with planning and management of the grid during normal operation and periods of malfunction, as well as required modifications to safety systems and grid configurations. This seventh appendix to the main report summarises and discusses the knowledge gained during the project and attempts to provide answers to various questions posed by the use of distributed power generation in ...

2003-07-01

309

Impact of oil and related chemicals on the marine environment  

International Nuclear Information System (INIS)

This review updates a previous review entitled ''Impact of Oil on the Marine Environment''. It covers oil and individual hydrocarbons, used lubricating oils, chemical control agents for oil spills, and wastes from offshore petroleum operations. It considers all major knowledge generated since the mid-1970s. The review covers its topics comprehensively, from a consideration of the composition, sources and inputs of oil to its ecological and human health effects and its effects on man's use of the sea. The review addresses several key questions on the present levels of contamination, the impact of hydrocarbons and related chemicals on marine biota, the recovery potential of marine ecosystems exposed to these contaminants, the degree of protection required for marine ecosystems known to be vulnerable and sensitive, and recommended research and other actions to fill gaps in knowledge. The review describes the hazards of marine oil pollution and associated chemicals and ...

310

From Light to Consciousness Journey to the End of Science or Fin de Siecle Malaise  

CERN Document Server

As the twentieth century gropes toward its uncertain conclusion, the pontification quotient increases. We hear that the end of history and science are near; that the questions we face today (in contrast with the end of the 19th century) are no longer soluble or present theories verifiable. These arguments will be examined using two examples. The first, familiar to all physicists, already resides securely in the museum of intellectual achievement. The second is a work in progress : the physiological and/or molecular basis for brain functions such as learning and memory storage. How do these lead to various higher level system properties - in particular, consciousness ? About consciousness, much has been said and written - not all of it illuminating. We discuss some of this, in particular a recent argument of Penrose. We consider whether the nature of consciousness is a (possibly) soluble scientific question. If so, how should it be posed ? ...

1996-01-01

311

Apollo II - Thermal use of chicken droppings - Phase II; Apollo II - Thermische Nutzung von Huehnermist, Phase II  

Energy Technology Data Exchange (ETDEWEB)

This report made for the Swiss Federal Office of Energy (SFOE) discusses the conception, planning and construction of an easy-to-operate pilot heating plant that uses chicken litter as its fuel. The plant, which is installed at a chicken farm in Boesingen, Switzerland, produces 250 - 350 kW and not only supplies heat for two chicken sheds and two households, but also provides energy for a drying plant in summer. The results of measurements made on emissions are discussed and, within the framework of an eco-balance analysis, comparisons are made between the direct use of the droppings as manure or as a fuel. The cost-effectiveness of the plant is examined and the influence of plant size and other factors discussed. Further, legal questions concerning the use of chicken litter as a fuel for heating installations are discussed; the use of the droppings as a fuel is not foreseen in the legislation concerning water protection and airborne emissions of pollutants. ...

2001-07-01

312

Yeast as a Model System to Study Tau Biology  

Science.gov (United States)

Hyperphosphorylated and aggregated human protein tau constitutes a hallmark of a multitude of neurodegenerative diseases called tauopathies, exemplified by Alzheimer's disease. In spite of an enormous amount of research performed on tau biology, several crucial questions concerning the mechanisms of tau toxicity remain unanswered. In this paper we will highlight some of the processes involved in tau biology and pathology, focusing on tau phosphorylation and the interplay with oxidative stress. In addition, we will introduce the development of a human tau-expressing yeast model, and discuss some crucial results obtained in this model, highlighting its potential in the elucidation of cellular processes leading to tau toxicity.

2011-04-06

313

U.S. Government Capabilities to Support Analysis of Gamma Ray Data Submitted by Field Elements  

Energy Technology Data Exchange (ETDEWEB)

As radiation detection in the interest of national security becomes increasingly commonplace, inevitable questions arise concerning the interpretation of data from handheld radioisotope identifiers (RIIDs). Field elements typically require fast answers to provide an effective defense and to minimize the impact on legitimate movement of people and goods. To support this need, on-call experts at Sandia, Los Alamos, and Lawrence Livermore national laboratories cooperate in resolving radiation alarms rapidly and accurately. We present an overview, describe the work in progress to improve capabilities, and report on some of the lessons learned.

2005-07-07

314

The nature of gas hydrates  

Energy Technology Data Exchange (ETDEWEB)

Gas hydrates have impacted the oil and gas industry since 1934, when they were first found to plug pipelines. Today we know that in deep oceans and in permafrost, very substantial gas reserves are present in hydrated form. Concerns are being raised about in situ dissociation for both energy and greenhouse implications upon methane release. In Japan work is underway to consider the storage of carbon dioxide, concentrated in clathrates. This talk will deal with some basic questions. Why should we be interested in gas hydrates? What are gas hydrates? How do gas hydrates form? How might hydrates impact on the energy/environmental picture?

1995-12-31

315

The benefits of low level radiation  

Energy Technology Data Exchange (ETDEWEB)

The assumed linear relationship between exposure to radiation and cancer incidence is questioned in this article. The current research data on radiation effects at the cellular level is reviewed, as are epidemiological studies of background radiation effects and health effects of populations exposed to low levels of radiation exposure via employment or medical treatments. Statistics reveal that threshold levels currently in force need to be reviewed. Some evidence of beneficial effects of low level radiation exposure effects of low level radiation exposure is also presented, and so regulations should be reviewed at an international level. (UK).

1997-06-01

316

Spatial heterogeneity and ecological models. [Predation  

Energy Technology Data Exchange (ETDEWEB)

The role of natural enemies in the regulation of populations is one of the major questions facing population ecologists. Simplification have led to two theoretical ways of incorporating the role of natural enemies in single ecological models: diffusion models and patch-type models. The predictions of the models are different because of the way variability is incorporated. Three equations are presented for diffusion models and one for patch models. Since the two types of models apply at different combinations of spatial and temporal scales, the right model(s) to choose for a particular study requires careful assessment. A continuing dialogue between experimentalists and theoreticians will lead to a better understanding of natural systems such as those that occur in biological control.

1990-04-01

317

Section 508 and Electronic Information Technology Accessibility at EPA | US EPA  

Wastenet

...Section 508 and Electronic Information Technology Accessibility at EPA | US EPA Jump to main content. Section 508 and Electronic Information Technology ...Us Search: All EPA Advanced search You are here: EPA Home Section 508 and Electronic Information Technology Accessibility at EPA Welcome to the United ... Section 508 of the Rehabilitation Act mandates that Federal departments and agencies make electronic and information technology (EIT) accessible to individuals ... Achieving compliance with Section 508 is an ongoing process. If you have any problems or questions about accessing information on a particular ...

318

Scaling and performance of a 3-D radiation hydrodynamics code on message-passing parallel computers: final report  

Energy Technology Data Exchange (ETDEWEB)

This report details an investigation into the efficacy of two approaches to solving the radiation diffusion equation within a radiation hydrodynamic simulation. Because leading-edge scientific computing platforms have evolved from large single-node vector processors to parallel aggregates containing tens to thousands of individual CPU's, the ability of an algorithm to maintain high compute efficiency when distributed over a large array of nodes is critically important. The viability of an algorithm thus hinges upon the tripartite question of numerical accuracy, total time to solution, and parallel efficiency.

1999-10-28

319

Risk-orientated analysis of the SNR 300. Technical report 1. Risk assessment of the fast breeder reactor. Risikoorientierte Analyse zum SNR 300. Fachbericht 1. Risikobewertung des Schnellen Brueters  

Energy Technology Data Exchange (ETDEWEB)

The study required by the West German Ministry of Research and Technology (RS 605) for the Committee on 'Future Nuclear Energy Policy' of the 9th German Parliament is concerned with the following main points: 1) Assessment of technical risks from the social aspect; 2) Discussion of terms and quantification of risks; 3) 'Engineering judgment' and 'questionable' methods in the Fast Breeder analysis of the Society for Reactor Safety (GRS); 4) Assessment criteria of potential damage.

1983-09-01

320

Radiological quality of marine and continental waters of the Normandy littoral; Qualite radiologique des eaux marines et continentales du littoral normand  

Energy Technology Data Exchange (ETDEWEB)

The work opened by the A.C.R.O. is in line with in an initiative of evaluation of the radiological quality of marine and continental waters of the Normandy coast. In this perspective, measures of radioactivity were made, not near an emissary (already very watched environment) but in more large scale because in marine environment, more than 640 km of coast are concerned. It was a question of supplying a representative assessment of the radioecological situation, for one year,of the marine environment (along the Normandy coast) and main streams which supplies it. (N.C.)

2000-09-15

321

Physics with Polarized Antiprotons  

Energy Technology Data Exchange (ETDEWEB)

Polarized antiprotons produced by spin filtering with an internal polarized gas target provide access to a wealth of single- and double-spin observables, thereby opening a window to physics uniquely accessible with the HESR at FAIR. This includes a first measurement of the transversity distribution of the valence quarks in the proton, and a first measurement of the moduli and the relative phase of the time-like electric and magnetic form factors G{sub E,M} of the proton. In polarized and unpolarized pp-bar elastic scattering open questions like the contribution from the odd charge-symmetry Landshoff-mechanism at large |t| and spin-effects in the extraction of the forward scattering amplitude at low |t| can be addressed.

2006-04-15

322

Oral histories at the Hanford Nuclear Reservation  

Energy Technology Data Exchange (ETDEWEB)

The founding of the Hanford Engineering Works to produce plutonium is described. The 45-year defense mission has now been replaced with a peaceful mission, that of being the first site for massive cleanup of the 45-year nuclear waste. In order to establish a remedial investigation and feasibility plan, a process of discovery named the Technical Baseline Report must be performed; the task of this process is to discover all that is known about a proposed cleanup site (what the waste was, where did it go). When none of the documentation can answer the question, oral history is utilized. Some of the problems associated with the conduct of oral history interviews are described, particularly Hanford`s legacy of secrecy.

1992-03-01

323

On the effects of low radiation doses  

International Nuclear Information System (INIS)

The prevailing hypothesis of linear extrapolation from high to low radiation doses without any threshold level is being questioned more and more strongly for radiobiological and epidemiological reasons and, consequently, also on socio-economic and ethical grounds. A cost-benefit analysis based on scientific facts and made plausible to the general public, concentrating on a comparison with demonstrable natural and manmade risks, most probably would result not only in the permissible limits being raised by a considerable margin, but also in billions of costs saved, and in greater acceptance of all peaceful uses of radiation, nuclear power included. (orig.)

1998-10-01

324

On Witten's instability and winding tachyons  

Energy Technology Data Exchange (ETDEWEB)

We investigate, from a spacetime perspective, some aspects of Horowitz's recent conjecture that black strings may catalyze the decay of Kaluza-Klein spacetimes into a bubble of nothing. We identify classical configurations that interpolate between flat space and the bubble, and discuss the energetics of the transition. We investigate the effects of winding tachyons on the size and shape of the barrier and find no evidence at large compactification radius that tachyons enhance the tunneling rate. For the interesting radii, of order the string scale, the question is difficult to answer due to the failure of the {alpha}' expansion.

2006-12-15

325

NRC safety research priorities for reactor vessel embrittlement, annealing, and surveillance dosimetry  

Energy Technology Data Exchange (ETDEWEB)

The recent definition of a postulated thermal shock accident followed promptly by system repressurization, termed an overcooling or pressurized thermal shock accident, has set a large analysis and research effort into motion. The essential elements are concerned with defining the accident transients, evaluating the instrumentation and controls that cause the postulated accidents, and evaluating the metallurgical and structural mechanics aspects of the reactor vessel with respect to its failure potential. This paper poses the question faced by the Nuclear Regulatory Commission (NRC) for the vessel steel embrittlement, annealing, and surveillance dosimetry facets of this postulated accident and provides information on our plans for study of this problem as well as current status.

1981-10-01

326

Mitochondrial DNA variants in Drosophila melanogaster are expressed at the level of the organismal phenotype.  

Science.gov (United States)

A plethora of experimental studies use mtDNA as a marker of demographic processes without questioning the possibility that selection may bias their interpretations. We studied four lines of Drosophila melanogaster that have a standardized nuclear DNA but variable mtDNA. We completed the sequencing of the mitochondrial genomes (excluding the A+T rich region) and compiled the differences. We then assayed male influence on oviposition, starvation resistance, lipid proportion and physical activity. We discuss these results in terms of the known differences between the lines and conclude that naturally occurring mtDNA variants in D. melanogaster are expressed at the level of the organismal phenotype. PMID:21757031

2011-07-05

327

Method for syndrome coding and its application to fast hardware data selection based on the processors operating in the GF(2sup(m)) Galois field  

International Nuclear Information System (INIS)

The method of syndrome coding for data compression read out from multiwire proportional chambers that has been previously proposed is generalized in case of its application to registration of the coordinates of events detected. The questions of execution of arithmetic and algebraic operations on the Galois field elements and their hardware implementation are considered. The method of computation is presented of a specialized processor for parallel computing the coordinates of three sparks. The estimate of its speed is equal to 185 ns. Data compression, data selection and coordinate calculations are performed without use of memory elements and timing pulses.

328

Leadership, communication and decision making in man-machine systems; Fuehrung, Kommunikation und Entscheidungsfindung in Mensch-Maschine-Systemen  

Energy Technology Data Exchange (ETDEWEB)

The contribution under consideration spans a wide curve from the first deadly accident of motorized aviation in the year 1908 up to newer tendencies of the so-called team resources management on observation points and control stations in order to pursue fundamental questions in man-machine systems. A continuous differentiation in the consideration of the factor human beings in complex technical systems is described. This is illustrated by the example of concepts for leadership, communication and decision making on observation points and control stations.

2008-07-01

329

Justice and the Human Genome Project  

Energy Technology Data Exchange (ETDEWEB)

Most of the essays gathered in this volume were first presented at a conference, Justice and the Human Genome, in Chicago in early November, 1991. The goal of the, conference was to consider questions of justice as they are and will be raised by the Human Genome Project. To achieve its goal of identifying and elucidating the challenges of justice inherent in genomic research and its social applications the conference drew together in one forum members from academia, medicine, and industry with interests divergent as rate-setting for insurance, the care of newborns, and the history of ethics. The essays in this volume address a number of theoretical and practical concerns relative to the meaning of genomic research.

1992-01-01

330

Influence of chromatin molecular changes on RNA synthesis during embryonic development  

International Nuclear Information System (INIS)

Two aspects of the chromatin repeat length (r_l) are discussed: (i) Why is r_l longer for slowly dividing cells than in rapidly dividing cells?, and (ii) Why is the temporal evolution of r_l a decreasing function of time (t) in mammalian cortical neurons whereas it is an increasing function of t for granule cells around the time of birth? These questions are discussed in terms of a hypothesis which assumes a correlation between deoxyribonucleic acid (DNA) packaging, transcription, and replication. (author). 27 refs.

331

Influence of UMTS mobile phone microwave fields on the muscular system; Einfluss von Mikrowellenfeldern des UMTS Mobilfunks auf das muskulaere System  

Energy Technology Data Exchange (ETDEWEB)

Two hypotheses are in the centre of this investigation, on the one hand the question, whether microwaves as exogenous fields alone are able to stimulate human muscle cells above-threshold, and on the other hand, whether microwaves as conditioning to cathodical electrical pulses can modify the excitation threshold and form. No excitation through the application of microwaves alone can be introduced at any subject. The conditioning of above-threshold cathodical electrical pulses with UMTS-microwaves leads not to a transgression of the threshold or the electrical muscle response (EMG) depending on the amplitude, the duration or the dose rate. (orig.)

2004-07-01

332

How quantum is the big bang?  

CERN Document Server

When quantum gravity is used to discuss the big bang singularity, the most important, though rarely addressed, question is what role genuine quantum degrees of freedom play. Here, complete effective equations are derived for isotropic models with an interacting scalar to all orders in the expansions involved. The resulting coupling terms show that quantum fluctuations do not affect the bounce much. Quantum correlations, however, do have an important role and could even eliminate the bounce. How quantum gravity regularizes the big bang depends crucially on properties of the quantum state.

2008-01-01

333

Harmonic oscillator representation in the theory of scattering and nuclear reactions  

Energy Technology Data Exchange (ETDEWEB)

The following questions, concerning the application of the harmonic oscillator representation (HOR) in the theory of scattering and reactions, are discussed: the formulation of the scattering theory in HOR; exact solutions of the free motion Schroedinger equation in HOR; separable expansion of the short range potentials and the calculation of the phase shifts; `isolated states` as generalization of the Wigner-von Neumann bound states embedded in continuum; a nuclear coupled channel problem in HOR; and the description of true three body scattering in HOR. As an illustration the soft dipole mode in the (11)Li nucleus is considered in a frame of the (9)Li+n+n cluster model taking into account three body continuum effects.

1995-01-01

334

Fundamental investigation of duct/ESP phenomena. Final report  

Energy Technology Data Exchange (ETDEWEB)

Radian Corporation was contracted to investigate duct injection and ESP phenomena in a 1.7 MW pilot plant constructed for this test program. This study was an attempt to resolve problems found in previous studies and answer remaining questions for the technology using an approach which concentrates on the fundamental mechanisms of the process. The goal of the study was to obtain a better understanding of the basic physical and chemical phenomena that control: (1) the desulfurization of flue gas by calcium-based reagent, and (2) the coupling of an existing ESP particulate collection device to the duct injection process. Process economics are being studied by others. (VC)

1991-10-21

335

Fundamental investigation of duct/ESP phenomena  

Energy Technology Data Exchange (ETDEWEB)

Radian Corporation was contracted to investigate duct injection and ESP phenomena in a 1.7 MW pilot plant constructed for this test program. This study was an attempt to resolve problems found in previous studies and answer remaining questions for the technology using an approach which concentrates on the fundamental mechanisms of the process. The goal of the study was to obtain a better understanding of the basic physical and chemical phenomena that control: (1) the desulfurization of flue gas by calcium-based reagent, and (2) the coupling of an existing ESP particulate collection device to the duct injection process. Process economics are being studied by others. (VC)

1991-10-21

336

Food and drink : Frequently asked questions : Soil Association  

Wastenet

... Do you certify Halal or Kosher meat? What fish feed do you allow? What levels of polychlorinated biphenyls (PCBs) have been found in organic fish? How can I be sure that organic products from abroad are really organic? Do you prosecute businesses that break the rules? Does the Soil Association carry out any routine testing of food? Do you test for GM material? Why do you allow additives in organic food? Is organic food fortified with vitamins and minerals? Why choose organic during pregnancy?...

337

Focus and the exclusion of alternatives: On the interaction of syntactic structure with pragmatic inference  

British Library Electronic Table of Contents (United Kingdom)

The claim that focus evokes a set of alternatives is a central issue in several accounts of the effects of focus on interpretation. This article presents two empirical studies that examine whether this property of focus is independent of contextual conditions. The syntactic operation at issue is object-fronting in German, Spanish, Greek, and Hungarian licensed by contexts involving focus on the object constituent. This operation evokes the intuition that the fronted referent excludes some or all relevant alternatives. The presented experiments deal with the question whether this interpretative property obligatorily accompanies the operation at issue or not. The empirical findings show that in German, Spanish, and Greek this intuition depends on properties of the context and is sensitive to...

2011-01-01

338

First-generation price-squeeze policy at the FERC  

Energy Technology Data Exchange (ETDEWEB)

A 1976 decision of the US Supreme Court made it clear that the Federal Energy Regulatory Commission (then the Federal Power Commission) has a responsibility to consider and determine allegations that proposed wholesale electric rates create a price squeeze against customers who compete with the wholesaler in making retail electric sales. This article reviews how the commission has approached the matter of discharging its newly recognized responsibility since that time, and describes its current position regarding the several issues and questions that price squeeze allegations raise. 35 references.

1982-09-30

339

Environmental scarcity: The international dimension  

Energy Technology Data Exchange (ETDEWEB)

National environmental policies have international repercussions: Thus the question arises as to how environmental policy should be designed in order to cope with international environmental problems in an efficient way. These topics were discussed in a conference held at the Kiel Institute of World Economics on July 5-6, 1990. The conference papers and comments are presented in this volume. Environmental scarcity has important international aspects. First, national environmental endowment and policy influence competitiveness and trade. Second, transfrontier pollution is a specific issue. Third, global environmental problems require a solution. This classification of the international aspects of the environmental issue provides the outline of the book. (orig./HSCH).

1991-01-01

340

Economic losses caused by air pollution  

Energy Technology Data Exchange (ETDEWEB)

While the expenses of pollution abatement measures are clearly defined at least by orders of magnitude there are no similar - not even internationally comprehensive and methodologically secured data available on the total economic cost of environmental pollution. The research program ' the cost of environmental pollution (efficiency of environmental policies)' aims at establishing a reliable data base. It is expected to be terminated in 1988. Evaluations are being complicated by a still incomplete knowledge and information. It is therefore obvious that economic losses as a result of air pollution can at present not be expressed in concrete figures and that extrapolations, too, are out of the question. (org./HSCH).

1987-01-21

341

Contract pricing of electric and telephone service: Current practice and policy  

Energy Technology Data Exchange (ETDEWEB)

Due mainly to competitive pressures, the practice of offering electric and telephone service under contracts or special tariffs negotiated individually between a utility and its customers has increased in importance in recent years. Moreover, the practice is likely to become still more widespread in the future. This creates questions of public policy that are of interest to regulators and ratepayers alike such as how to supervise the practice, how to encourage utilities to compete while preventing cross-subsidization and anticompetitive behavior, and how the practice will ultimately affect utilities and ratepayers. This report sheds light on the topic by describing approaches that have been taken by the various regulatory commissions and by providing a framework for analyzing such contractors.

1992-04-01

342

Clean Water Act (Section 404) and Rivers and Harbors Act (Sections 9 and 10). Environmental Guidance Program Reference Book, Revision 4  

Energy Technology Data Exchange (ETDEWEB)

This Reference Book contains a current copy of the Clean Water Act (Section 404) and the Rivers and Harbors Act (Sections 9 and 10) and those regulations that implement those sections of the statutes and appear to be most relevant to DOE activities. The document is provided to DOE and contractor staff for informational purposes only and should not be interpreted as legal guidance. Updates that include important new requirements will be provided periodically. Questions concerning this Reference Book may be directed to Mark Petts, IH-231 (FTS 896-2609 or Commercial 202/586-2609).

1992-03-01

343

Clean Water Act (Section 404) and Rivers and Harbors Act (Sections 9 and 10)  

Energy Technology Data Exchange (ETDEWEB)

This Reference Book contains a current copy of the Clean Water Act (Section 404) and the Rivers and Harbors Act (Sections 9 and 10) and those regulations that implement those sections of the statutes and appear to be most relevant to DOE activities. The document is provided to DOE and contractor staff for informational purposes only and should not be interpreted as legal guidance. Updates that include important new requirements will be provided periodically. Questions concerning this Reference Book may be directed to Mark Petts, IH-231 (FTS 896-2609 or Commercial 202/586-2609).

1992-03-01

344

Chiral crystallization and the origin of chiral life on earth  

British Library Electronic Table of Contents (United Kingdom)

Abstract The creation of chirality on Earth and the development of chiral life have been discussed in this highlight. Convincing evidence for the introduction of chirality on Earth is still fragmentary. We believe that by a combination of chiral crystallization and formation of helical polymers with preferred chiral conformational structure is the key to this question. This concept of macromolecular asymmetry has inspired ideas and resulted in possible rules for how chiral life as we know it, could have been introduced. These investigations needed the understanding of the requirements for chiral crystallization, for the stereochemistry of the initial formation of helical polymers, the measurements of optical activity of solids and their coordination with the fundamentals of chirality. Spac...

2011-01-01

345

CCNA Certification All-In-One For Dummies  

CERN Document Server

A complete preparation guide for the entry-level networking CCNA certification. If you're planning to advance your career by taking the all-important Cisco Certified Network Associate (CCNA), this is the study guide you need! Seven minibooks cover all the concepts and topics on which you'll be tested, covering the latest version of the exam. Each part of the exam is covered thoroughly in its own section, so you can readily find the information you want to study. Plenty of review questions help you prepare, and the companion CD-ROM includes the highly rated Dummies Test Engine so you can test y

2010-01-01

346

Anomaliously high radiation hardening of iron-chromium alloys  

International Nuclear Information System (INIS)

Argon ions irradiation of 12% Cr steels and Fe/Cr alloys results in the hardening up to 10000 MPa. This value exceeds the hardening level even for martensitic transformation. Along with the increase of microhardness following irradiation the shape of X-ray graph of the affected materials changes considerable. Hardening value and behavior are determined by temperature radiation doze, preliminary ageing, extent of cold strain and alloying. The odserved phenomenon is supposed to be caused by irradiation-induced structural transformations. Reversibility of radiation hardening of the materials in question was observed.

347

Affine cones over Fano threefolds and additive group actions  

CERN Document Server

We address the following question: When an affine cone over a smooth Fano threefold admits an effective action of the additive group? In this paper we deal with Fano threefolds of index 1 and Picard number 1. Our approach is based on a geometric criterion from our previous paper, which relates the existence of an additive group action on the cone over a smooth projective variety X with the existence of an open polar cylinder in X. Non-trivial families of Fano threefolds carrying a cylinder were found in loc. cit. Here we provide new such examples.

2011-01-01

348

Investigations of the structure and electromagnetic interactions of few-body systems. Progress report, 1 July 1991--30 June 1994  

Energy Technology Data Exchange (ETDEWEB)

In order to make it easy for the reader to see the specific research carried out and the progress made, the following report of progress is done by topic. Each item has a format layout of Topic, Investigators, Objective, Significance, and Description of Progress, followed at the end by the relevant references. As is clear from the topics listed, the emphasis of the GW nuclear theory group has been on the structure and electromagnetic interactions of few-body nuclei. Both low- and intermediate-energy electromagnetic disintegration of these nuclei is considered, including coherent photoproduction of {pi} mesons. When the excitation energy of the target nucleus is low, the aim has been to handle the continuum part of the theoretical work numerically with no approximations, that is, by means of full three- or four-body dynamics. When structure questions are the issue, numerically accurate calculations are always carried through, limited only by the underlying two-body ...

1994-07-01

349

A single amino acid substitution (R441A) in the receptor-binding domain of SARS coronavirus spike protein disrupts the antigenic structure and binding activity  

International Nuclear Information System (INIS)

The spike (S) protein of severe acute respiratory syndrome coronavirus (SARS-CoV) has two major functions: interacting with the receptor to mediate virus entry and inducing protective immunity. Coincidently, the receptor-binding domain (RBD, residues 318-510) of SAR-CoV S protein is a major antigenic site to induce neutralizing antibodies. Here, we used RBD-Fc, a fusion protein containing the RBD and human IgG1 Fc, as a model in the studies and found that a single amino acid substitution in the RBD (R441A) could abolish the immunogenicity of RBD to induce neutralizing antibodies in immunized mice and rabbits. With a panel of anti-RBD mAbs as probes, we observed that R441A substitution was able to disrupt the majority of neutralizing epitopes in the RBD, suggesting that this residue is critical for the antigenic structure responsible for inducing protective immune responses. We also demonstrated that the RBD-Fc bearing R441A mutation could not bind to soluble and cell-associated ...

2006-05-26

350

What comes first? Electrophysiological differences in the temporal course of memory and future thinking  

British Library Electronic Table of Contents (United Kingdom)

Abstract It is now widely accepted that remembering the past and imagining the future rely on a number of shared processes and recruit a similar set of brain regions. However, memory and future thinking place different demands on a range of processes. For instance, although remembering should lead to early associative retrieval of event details, event construction may be slower for future events, for which details from different memories are combined. In order to shed light on the question of how the brain distinguishes between memories and future thoughts, we investigated the differences in the electrophysiological correlates of the vivid elaboration of future and past events. In the slow cortical potentials of 24 healthy human participants, differences during early elaboration were obser...

2011-01-01

351

What can we learn about extragalactic radio jets from X-ray data?  

CERN Document Server

We review the current status of resolved X-ray emission associated with extragalactic radio jets and hotspots. The primary question for any particular jet is to decide if the X-rays come from the synchrotron process or from inverse Compton scattering. There is considerable evidence supporting synchrotron emission for knots in the jets of FRI galaxies. For FRII terminal hotspots detected in the X-ray band, synchrotron self-Compton emission continues to provide viable models with one possible exception (so far). Inverse Compton scattering on photons of the cosmic microwave background is indicated for a few powerful jets, and is expected to be an important contributor if not the dominating mechanism for higher redshift objects. The application of a model generally yields physical parameters and in many cases, these include the Doppler boosting factor.

2003-01-01

352

Web-based tools for modelling and analysis of multivariate data: California ozone pollution activity  

British Library Electronic Table of Contents (United Kingdom)

This article presents a hands-on web-based activity motivated by the relation between human health and ozone pollution in California. This case study is based on multivariate data collected monthly at 20 locations in California between 1980 and 2006. Several strategies and tools for data interrogation and exploratory data analysis, model fitting and statistical inference on these data are presented. All components of this case study (data, tools, activity) are freely available online at: http://wiki.stat.ucla.edu/socr/index.php/SOCR_MotionCharts_CAOzoneData. Several types of exploratory (motion charts, box-and-whisker plots, spider charts) and quantitative (inference, regression, analysis of variance (ANOVA)) data analyses tools are demonstrated. Two specific human health related questions...

2011-01-01

353

Waqf in Turkestan: the colonial legacy and the fate of an Islamic institution in early Soviet Central Asia, 1917-1924  

British Library Electronic Table of Contents (United Kingdom)

The paper investigates early Soviet policies regarding the institution of waqf (charitable endowment) in Turkestan, questioning the issue of the post-colonial character of the early Soviet administration. After taking into consideration practices related to waqf management in modern Muslim states and European colonial empires, the paper briefly describes the tsarist administrative approach to the issue. We then address the ambiguity inherent in Soviet policies on waqf requisition and restitution during Civil War years. In the section that follows we deal with different groups of Muslim intellectuals that attempted to use the Soviet state in their mutual struggle over authority in Central Asian society and describe the creation and functioning of the bureaucracies responsible for managing w...

2007-01-01

354

Using topographic wetness index in vegetation ecology: does the algorithm matter?  

British Library Electronic Table of Contents (United Kingdom)

Abstract Questions: How important is the choice of flow routing algorithm with respect to application of topographic wetness index (TWI) in vegetation ecology? Which flow routing algorithms are preferable for application in vegetation ecology? Location: Forests in three different regions of the Czech Republic. Methods: We used vegetation data from 521 georeferenced plots, recently sampled in a wide range of forest communities. From a digital elevation model, we calculated 11 variations of TWI for each plot with 11 different flow routing algorithms. We evaluated the performance of differently calculated TWI by (1) Spearman rank correlation with average Ellenberg indicator values for soil moisture, (2) Mantel correlation coefficient between dissimilarities of species composition and dissimil...

2010-01-01

355

Using Multimedia Learning Modules in a Hybrid-Online Course in Electricity and Magnetism  

Science.gov (United States)

We have been piloting web-based multimedia learning modules (MLMs), developed by the Physics Education Research Group at the University of Illinois at Urbana Champaign (UIUC), as a "prelecture assignment" in several introductory physics courses at California State Polytechnic University at Pomona. In this study, we report the results from a controlled study utilizing modules on electricity and magnetism as a part of a blended hybrid-online course. We asked students in the experimental section to view the MLMs prior to attending the face-to-face class, and to make sure this would not result in additional instructional time, we reduced the weekly class time by one-third. We found that despite reduced class time, student-learning outcomes were not hindered; in fact, the implementation of the UIUC MLMs resulted in a positive effect on student performance on conceptual tests and classroom discussion questions. (Contains 4 figures and 1 table.)

2010-12-01

356

Types of nonanticlinal oil and gas traps and their dispersal within the island section of North Sakhalin  

Energy Technology Data Exchange (ETDEWEB)

Questions are examined of prospecting for nonanticlinical traps within North Sakhalin, their spatial distribution and evaluation of the outlook for oil and gas content. Traps of tapering and facial substitution on wings and periclines of local elevations, accumulative bar and erosion-accumulative channel are isolated. THe hypothesis is made that it is possible to form stratigraphic traps above the discrepancy and below it. It is noted that formation of zones of lithological tapering and facial substitution are associated with areas of the exchange of the sedimentation situation. The primary role of the shore and coastal zones in the formation of the examined types of nonanticlinal traps is established. The Okhino-Ekhabinskiy region in North Sakhalin is isolated as the primary object for prospecting for nonanticlinal traps.

1981-01-01

357

Traumatic and Non-traumatic Fibromyalgia Syndrome: Impact Assessment on the Life Quality of Women  

British Library Electronic Table of Contents (United Kingdom)

Objective To investigate the impact on life quality of women with traumatic and non-traumatic origin fibromyalgia syndrome [FMS]. Method Women affected with FMS were selected and divided into two groups: those with traumatic origin FMS [Group 1] and those with non-traumatic origin FMS [Group 2]. A standard question form was used for the research, as well as the fibromyalgia impact questionnaire [FIQ] for evaluation of life quality. Results Seventy-two patients, 34 for Group 1 and 38 for Group 2 were analyzed. The main triggering symptoms were divorce [23.5 percent of cases] and death in the family [23.5 percent of cases]. In addition to diffuse pain, the main symptoms presented were poor sleep quality, weariness, and paresthesia, with no difference between the groups; migraine had a greate...

2011-01-01

358

To Beta Test, or Not to Beta Test: Is That the Question?  

British Library Electronic Table of Contents (United Kingdom)

Purpose - The purpose of this paper is to help library technology staff understand the process of beta testing software, determine if it is appropriate for them to engage in the process, and provide suggestions on how to the time invested in the process. Design/methodology/approach - The paper explains what beta testing is, why it should be used and how to become a beta tester. Findings - The paper reveals that beta testing is not convenient for everyone, but those taking place in these activities should be thorough, positive and generous in order to maximize the return on investment in this kind of testing. Practical Implications - While beta testing new software features can take a significant amount of time, the resulting benefits of early access to new features and improved vendor-staf...

2008-01-01

359

The questions of liquid metal two-phase flow modelling in the FBR core channels  

International Nuclear Information System (INIS)

The two-fluid model representation for calculations of two-phase flow characteristics in the FBR fuel pin bundles with liquid metal cooling is presented and analysed. Two conservation equations systems of the mass, momentum and energy have been written for each phase. Components accounted the mass-, momentum- and heat transfer throughout the interface occur in the macro-field equations after the averaging procedure realisation. The pattern map and correlations for two-fluid model in vertical liquid metal flows are presented. The description of processes interphase mass- and heat exchange and interphase friction is determined by the two-phase flow regime. The opportunity of the liquid metal two-phase flow regime definition is analysed. (author)

2000-06-01

360

The map equation  

CERN Document Server

Many real-world networks are so large that we must simplify their structure before we can extract useful information about the systems they represent. As the tools for doing these simplifications proliferate within the network literature, researchers would benefit from some guidelines about which of the so-called community detection algorithms are most appropriate for the structures they are studying and the questions they are asking. Here we show that different methods highlight different aspects of a network's structure and that the the sort of information that we seek to extract about the system must guide us in our decision. For example, many community detection algorithms, including the popular modularity maximization approach, infer module assignments from an underlying model of the network formation process. However, we are not always as interested in how a system's network structure was formed, as we are in how a network's extant structure influences the ...

2009-01-01

361

The impact of available information on negotiation results  

British Library Electronic Table of Contents (United Kingdom)

Negotiation is the most famous tool for reaching an agreement between parties. Usually, the different parties can be modeled as a buyer and a seller, who negotiate about the price of a given item. In most cases, the parties have incomplete information about one another, but they can invest money and efforts in order to acquire information about each other. This leads to the question of how much each party will be willing to invest on information about its opponent, prior to the negotiation process. In this paper, we consider the profitability of automated negotiators acquiring information on their opponents. In our model, a buyer and a seller negotiate on the price of a given item. Time is costly, and incomplete information exists about the reservation price of both parties. The reservatio...

2010-01-01

362

The effect of thermally pulsating asymptotic giant branch stars on the evolution of the rest-frame near-infrared galaxy luminosity function  

British Library Electronic Table of Contents (United Kingdom)

Abstract We address the fundamental question of matching the rest-frame K-band luminosity function (LF) of galaxies over the Hubble time using semi-analytic models after modification of the stellar population modelling. We include the Maraston evolutionary synthesis models, which feature a higher contribution by the thermally pulsating asymptotic giant branch (TP-AGB) stellar phase, into three different semi-analytic models, namely the De Lucia and Blaizot version of the Munich model, morgana and the Menci model. We leave all other input physics and parameters unchanged. We find that the modification of the stellar population emission can solve the mismatch between models and the observed rest-frame K-band luminosity from the brightest galaxies derived from UKIRT Infrared Deep Sky Survey d...

2011-01-01

363

The effect of neutrals on the performance of plasma opening switches  

Energy Technology Data Exchange (ETDEWEB)

The authors address the question of the limitations on voltage and current transfer to loads in magnetic storage systems utilizing microsecond conduction time plasma opening switches. They propose that the limitation of performance results from neutral atoms that are not entrained into the ionized material that is driven by the magnetic field of the rising generator current. Evidence in support of this proposition is gathered from experiments performed on the Ace-4 and Hawk generators. They set forth a theory to describe the effect of neutrals on the electrical performance of plasma opening switches. The neutral gas is assumed to be present in the region between the moving plasma mass and the generator, primarily in the region in which the plasma is injected initially. The essential elements of the theory are a weak photoionization source to seed the gas with a low concentration of electrons, and joule heating accompanied by further ionization and breakdown of the ...

1996-12-31

364

The determination of the tuning of a Power System Stabilizer (PSS). De bepaling van de instelling van een Power System Stabilizer  

Energy Technology Data Exchange (ETDEWEB)

By means of an analogous simulator, which can simulate a power supply system, a method to determine the transfer function of a Power System Stabilizer (PSS) is developed. The purpose of the PSS is to damp unwanted electro-mechanical oscillations. The method is very systematic and there is no need for specified values of the parameters used in the system. It is assumed that the power generator system is linear for small variations. The system can be considered to be a black box. Measurements executed by means of this method are completely controlled by the person who enforces the measurement. By applying this method carefully, irregularities are almost out of the question. The equipment necessary are a PC with two AD-ports and an adjustable sinus-generator. A comparison is made with a more traditional method, in which a spectrum analyzer is used. 4 figs., 7 refs.

1992-10-01

365

The application of expert systems technology to rotating machine condition monitoring  

Energy Technology Data Exchange (ETDEWEB)

An expert system was developed which helps maintenance personnel diagnose the condition of rotor and stator windings and their cores, in motors and generators rated 2300 V and above. The expert system, called MICAA[TM], used an approach which has been found to be effective for diagnosing medical problems. The program required the user to input machine nameplate information, operating status, and any past test data available. In addition, the program would suggest tests that may be useful, as well as provide guidance to maintenance personnel on what to look for in visual inspections of the machine. The expert system stored and correlated all this information, calculated the overall condition of the component in question, and identified the most likely specific causes of any deterioration. The basic methodology of motor and generator condition assessment, and the architecture and processing performed by MICAA to obtain these capabilities were discussed and described. ...

1995-12-31

366

The Waste of the World  

Environmental Research Database

ObjectivesThis programme aims; To rethink how waste is thought about in social science; To provide a global analysis of waste; To examine how rethinking waste impinges on core social science concerns, notably: economies, researching globalisation, hazards and risk, and materiality. Social science understandings of waste position waste as the end-point of production and consumption, and see waste as a question of disposal.DescriptionThe Waste of the World is a five year research programme funded under ESRC's Large Grant Scheme. It brings together researchers in geography, anthropology and materials science from the University of Sheffield, Durham University, University College London and Goldsmiths College London, and connects the UK with South Asia (particularly India and Bangladesh), as well as the US, Europe and Kazakhstan. The over-arching aims of the programme are: To rethink how waste is thought about in the social [continued...

2011-01-30

367

The Use of Knowledge: Conceptual Problems and Empirical Confusions. Occasional Paper No. 57.  

Science.gov (United States)

Four questions are posed: (1) Is knowledge utilization a rhetorical evocation? (2) Is the conjunction of knowledge with utility part of a cultural system of common sense? (3) Is utility a normative or a descriptive concept? and (4) How does the concept of knowledge utilization figure in the specialized discourse of social scientists? This paper analyzes the concept of knowledge utilization from the perspective of philosophy of language and philosophy of science. Knowledge utilization is a rhetorical evocation that implies concepts of action and knowledge. It is supported by two conceptual fusions. The fusion of value and utility draws on common sense, but does not exhaust colloquial understandings about knowledge and action. The conceptual fusion of knowledge and truth is consistent with common sense but disregards scientific criticism. Both conceptual fusions are thus problematic. But empirical conditions associated with the concept of knowledge utilization mask ...

1982-07-01

368

The Neural control of mood: The possible role of the adrenergic system in the medulla  

British Library Electronic Table of Contents (United Kingdom)

Mood in humans is a complex phenomenon that integrates emotion (e.g. happiness and sadness), cognition, perception, ideation, and action in a coherent manner. In bipolar disorder extremes of mood (up or down) occur outside the normal range, in which all the above functions are coherently affected. Mood is controlled by a series of separate but interactive brain circuits that involve much of the brain, but particularly the limbic system. The question addressed in this paper is whether the coordination of all these separate systems into one coherent functional mood is mediated by non-linear dynamics acting between these systems as equal participants; or whether it is affected by a single master regulator controlling the others. The possible roles, as master regulators, of non-linear dynamica...

2011-01-01

369

The Meaning of Cause and Prevent: The Role of Causal Mechanism  

British Library Electronic Table of Contents (United Kingdom)

How do people understand questions about cause and prevent? Some theories propose that people affirm that A causes B if A's occurrence makes a difference to B's occurrence in one way or another. Other theories propose that A causes B if some quantity or symbol gets passed in some way from A to B. The aim of our studies is to compare these theories' ability to explain judgements of causation and prevention. We describe six experiments that compare judgements for causal paths that involve a mechanism, i.e. a continuous process of transmission or exchange from cause to effect, against paths that involve no mechanism yet a change in the cause nevertheless brings about a change in the effect. Our results show that people prefer to attribute cause when a mechanism links cause to effect. In contr...

2011-01-01

370

The French Electricity Company (EDF) and the environment. Press file for 1996; EDF et l'environnment 1996. Dossier de presse  

Energy Technology Data Exchange (ETDEWEB)

In 1996 the actions of EDF in the domain of environment have recorded FF 4 billions (FF 3.5 billion in 1995), representing about 2% of the EDF's turnover. The EDF keeps on its efforts for reducing the impact of its activities upon environment. Several applications of an environment protective electricity generation are promoted by the company. The company brings services and technical solutions to its clients which meet their energy needs and conserving at the same time the life conditions. Furthermore, EDF participates in the activity of numerous national and international organisms, intervening in the environmental questions, in decision making, participating in studies and actions and following continually the direction of a durable economic and social development. The report is structured in three chapters: 1. an industrial responsibility; 2. services and techniques for environment; 3. action towards a durable development.

1997-03-27

371

The Chernobyl plant shutdown; L'arret de la centrale de Tchernobyl  

Energy Technology Data Exchange (ETDEWEB)

The Chernobylsk-1 reactor, operational in september 1977 has been stopped in november 1996; the Chernobylsk-2 reactor started in november 1978 is out of order since 1991 following a fire. The Chernobylsk-3 reactor began in 1981. During the last three years it occurs several maintenance operations that stop it. In june 2000, the Ukrainian authorities decided to stop it definitively on the 15. of december (2000). This file handles the subject. it is divided in four chapters: the first one gives the general context of the plant shutdown, the second chapter studies the supporting projects to stop definitively the nuclear plant, the third chapter treats the question of the sarcophagus, and the fourth and final chapter studies the consequences of the accident and the contaminated territories. (N.C.)

2000-12-01

372

Teaching and Learning Guide for: Fairness and Power in Family Organization  

British Library Electronic Table of Contents (United Kingdom)

This guide accompanies the following article: Gabrielle Poeschl, `What Family Organization Tells Us about Fairness and Power in Marital Relationships', Social and Personality Compass 1/1 (2007): 557-571, 10.1111/j.1751-9004.2007.00026.x Author's Introduction One thing that often strikes me, when I talk with people, is the human capacity to accept and defend surprising aspects of the social life. Thus, we have some feeling that the separation between the domestic and the public spheres has not always existed, but we are ready to assume that in the first human groups, men went out hunting to feed their family, while women stayed in the camp to take care of the children. Even in the face of evidence to the contrary, we are reluctant to question the opinion that men and women differ in persona...

2009-01-01

373

Sustainability as an educational agenda  

British Library Electronic Table of Contents (United Kingdom)

The mounting evidence about human-induced environmental change, and about its expected detrimental effects on humans and their societies (IPCC, 2007; Reid et al., 2010; Rockstrom et al., 2009), has turned out to be exceedingly difficult to turn into political action to mitigate the change and adapt to its consequences. Economic self-interest creates friction between nation-states, within regional alliances like the EU, and across the divide between the developing and developed world. A significant factor is a vocal and well-funded group of climate skeptics, who question the credibility of mainstream earth system science, overemphasize the disagreements within the scientific community, argue for more research before any action is warranted, and in general create doubt to justify inaction or...

2011-01-01

374

Study of questions of reliability of planning mining operations at open pits  

Energy Technology Data Exchange (ETDEWEB)

A method is proposed for evaluating reliability of planning and calculation of the reliability factor with current planning of open pit mining operations. For a quantitative evaluation of the reliability of fulfilling the planned assignment, laws were defined for distribution of the quality characteristics of the coal. After establishing that coal ash content follows the normal distribution law, the probability was defined that the actual output of coal is greater or equal to the planned. Calculation of the factor of reliability of the current planning of open mining operations makes it possible to determine the optimum planning for this period and the probability of fulfillment of the planned assignments. The technique of planning with regard for reliability makes it possible to select the most reliable variant of the plan within the planning period.

1982-01-01

375

Stream, lake, estuary, and ocean pollution, 2nd edition  

Energy Technology Data Exchange (ETDEWEB)

This book, an updated version of the 1985 edition, contains thirteen chapters, beginning with a preface which provides the objective of the book. The primary objective is to offer a comprehensive survey of the biological, hydrological, mathematical, and biochemical aspects of stream, lake, estuary, and ocean pollution analysis. The book also contains ten appendices of useful tables and nomographs of pertinent data. This book provides a very good summary and review of stream, lake, estuary, and ocean pollution. This book is recommended for environmental engineering students, environmental consulting engineers, and regulatory personnel. It provides an excellent summary of the field of stream and lake analysis and modeling. Every chapter includes a significant number of questions and pertinent references.

1991-01-01

376

Steam generators ? horizontal or vertical (which type should be used in nuclear power plants with VVER?)  

British Library Electronic Table of Contents (United Kingdom)

The steam generator is a very important component of a nuclear power plant. Historically, vertical steam generators came to be used abroad and horizontal steam generators in our country. Both types of steam generators operate successfully in nuclear power plants and satisfactorily fulfill their functions, enabling the production of electricity. Repeated attempts to re-examine the existing concepts in one or another country have been unsuccessful because there are no convincing arguments for this. Nonetheless, the question of using a different type of steam generator is raised periodically in our country and abroad. This article briefly reviews different concepts of steam generators. Their parameters, characteristics, and thermal efficiency are compared and ways to increase the latter are a...

2008-01-01

377

Statoil's Material Expectations for Pipelines  

Energy Technology Data Exchange (ETDEWEB)

Pipelines are normally made in low-alloyed steels and the design is based on technical and economical criteria. For the transportation of corrosive fluids, a corrosion evaluation will determine what materials can be used. In the event that stainless steel must be used, investment costs will increase significantly. Use of life cycle cost evaluation may also apply, but we may question how often that is used properly. One must, furthermore, differ between onshore and offshore pipelines, because of differences in pipe laying conditions and in maintenance and repair costs. The consequences of a rupture may differ dramatically between onshore pipelines, too, i.e. a large gas pipeline in a populated area and a small oil pipeline in a nonpopulated area. (author)

2003-07-01

378

Statistical methods for environmental pollution monitoring  

Energy Technology Data Exchange (ETDEWEB)

This volume covers planning, design, and data analysis. It offers statistical methods for designing environmental sampling and monitoring programs as well as analyzing the resulting data. Statistical sample survey methods to problems of estimating average and total amounts of environmental pollution are presented in detail. The book also provides a broad array of statistical analysis methods for many purposes...numerous examples...three case studies...end-of-chapter questions...computer codes (showing what output looks like along with its interpretation)...a discussion of Kriging methods for estimating pollution concentration contours over space and/or time...nomographs for determining the number of samples required to detect hot spots with specified confidence...and a description and tables for conducting Rosner's test to identify outlaying (usually large) pollution measurements in a data set.

1986-01-01

379

Stability of the viscously spreading ring  

CERN Document Server

We study analytically and numerically the stability of the pressure-less, viscously spreading accretion ring. We show that the ring is unstable to small non-axisymmetric perturbations. To perform the perturbation analysis of the ring we use a stretching transformation of the time coordinate. We find that to 1st order, one-armed spiral structures, and to 2nd order additionally two-armed spiral features may appear. Furthermore, we identify a dispersion relation determining the instability of the ring. The theoretical results are confirmed in several simulations, using two different numerical methods. These computations prove independently the existence of a secular spiral instability driven by viscosity, which evolves into persisting leading and trailing spiral waves. Our results settle the question whether the spiral structures found in earlier simulations of the spreading ring are numerical artifacts or genuine instabilities.

2003-01-01

380

Sperm competition risk affects male mate choice copying  

British Library Electronic Table of Contents (United Kingdom)

Mate choice copying was mostly described as a strategy employed by females to assess the quality of potential mates, but also males can copy other males? mate choice. An open question in this context is whether and how copying males evaluate sperm competition risk, as mating with a female that has already copulated with another male obviously sets the stage for intense sperm competition (i.e., in species with internal fertilization). Using the livebearing Atlantic molly (Poecilia mexicana) as a model, we asked (a) whether males of that species indeed copy other males? choices, and if they do so, (b) whether copying males strategically adjust their behavior to sperm competition risk. We used an approach where focal males could first choose to associate with a large or a small stimulus femal...

2011-01-01

381

Spectral Analysis of Radial Dirac Operators in the Kerr-Newman Metric and its Applications to Time-periodic Solutions  

CERN Document Server

We investigate the existence of time-periodic solutions of the Dirac equation in the Kerr-Newman background metric. To this end, the solutions are expanded in a Fourier series with respect to the time variable $t$ and the Chandrasekhar separation ansatz is applied so that the question of existence of a time-periodic solution is reduced to the solvability of a certain coupled system of ordinary differential equations. First, we prove the already known result that there are no time-periodic solutions in the non-extreme case. Then it is shown that in the extreme case for fixed black hole data there is a sequence of particle masses $(m_N)_{N\\in\\mathbb N}$ for which a time-periodic solution of the Dirac equation does exist. The period of the solution depends only on the data of the black hole described by the Kerr-Newman metric.

2006-01-01

382

Soil seed bank dynamics in alpine wetland succession on the Tibetan Plateau  

British Library Electronic Table of Contents (United Kingdom)

The primary goal was to address several questions with regard to how soil seed banks change in a successional series. How does the composition of the viable seed bank change, and how does the relationship of the soil seed bank and vegetation change with succession? Can the seed bank be regarded as a potential as a source of seeds for wetland restoration? We collected soil seed bank samples and sampled the vegetation in four different successional stages and used the NMDS (nonmetric multidimensional scaling) to evaluate the relationship of species composition between the seed banks and vegetation. The difference of seed density and species richness in different habitats and soil depths also was compared. Viable seeds of half (37) the species in the early-successional stage were found in all...

2011-01-01

383

Software systems in-house integration: Architecture, process practices, and strategy selection  

British Library Electronic Table of Contents (United Kingdom)

As organizations merge or collaborate closely, an important question is how their existing software assets should be handled. If these previously separate organizations are in the same business domain - they might even have been competitors - it is likely that they have developed similar software systems. To rationalize, these existing software assets should be integrated, in the sense that similar features should be implemented only once. The integration can be achieved in different ways. Success of it involves properly managing challenges such as making as well founded decisions as early as possible, maintaining commitment within the organization, managing the complexities of distributed teams, and synchronizing the integration efforts with concurrent evolution of the existing systems.Th...

2007-01-01

384

Simulating the operation of photosensor-based lighting controls  

International Nuclear Information System (INIS)

Energy savings from the use of daylighting in commercial buildings are realized through implementation of photoelectric lighting controls that dim electric lights when sufficient daylight is available to provide adequate workplane illumination. The dimming level of electric lighting is based on the signal of a photosensor. Current simulation approaches for such systems are based on the questionable assumption that the signal of the photosensor is proportional to the task illuminance. This paper presents a method that simulates the performance of photosensor controls considering the acceptance angle, angular sensitivity, placement of the photosensor within a space, and color correction filter. The method is based on the multiplication of two fisheye images: one generated from the angular sensitivity of the photosensor and the other from a 180- or 360-degree fisheye image of the space as ''seen'' by the photosensor. The paper includes a detailed description of the ...

385

Sensitivity analysis: Interaction of DOE SNF and packaging materials  

International Nuclear Information System (INIS)

A sensitivity analysis was conducted to evaluate the technical issues pertaining to possible destructive interactions between spent nuclear fuels (SNFs) and the stainless steel canisters. When issues are identified through such an analysis, they provide the technical basis for answering what if questions and, if needed, for conducting additional analyses, testing, or other efforts to resolve them in order to base the licensing on solid technical grounds. The analysis reported herein systematically assessed the chemical and physical properties and the potential interactions of the materials that comprise typical US Department of Energy (DOE) SNFs and the stainless steel canisters in which they will be stored, transported, and placed in a geologic repository for final disposition. The primary focus in each step of the analysis was to identify any possible phenomena that could potentially compromise the structural integrity of the canisters and to assess their ...

1999-06-06

386

Self-valued health in Danish women after cervix cancer surgery-A retrospective questionnaire study  

British Library Electronic Table of Contents (United Kingdom)

Women treated of localised stages of cervix cancer have a very good prognosis. But do health care professionals have a tendency to underestimate the potential need for rehabilitation of this group? To be able to answer this question this study aimed to develop knowledge concerning these women's own perception of their health during a long period after surgical cancer treatment. A total of 398 women who underwent radical hysterectomy in the period from the 1 January 1983 to 31 December 2000 participated in the study at Aarhus University Hospital, Skejby in Denmark 2001-2003. All patients initially filled in an internally validated questionnaire. Subsequently a sample of 100 women filled in the questionnaires Short Form -36 and Sense of Coherence to evaluate their self-reported health. Analy...

2007-01-01

387

Screening for marine nanoplanktic microalgae from Greek coastal lagoons (Ionian Sea) for use in mariculture  

British Library Electronic Table of Contents (United Kingdom)

Mediterranean mariculture uses imported strains of marine phytoplankton, raising questions of ecological risk and ability to adapt to local conditions for mass culture outdoors. In this context, we report here on the mass-culture potential and chemical composition of six strains of Prasinophyceae (five strains of Tetraselmis sp. and one Pyramimonas sp.) isolated from a Greek coastal lagoon. Proximate composition had a pattern of 10?20% ash, 35?65% protein, 6?10% lipids, and 25?45% other organics including carbohydrates. The amino acid profiles were typical for the marine representatives of the class. All strains had a high PUFA content with dominant the ?3 fraction in four of them. The fatty acid profiles indicated a Tetraselmis strain with high EPA (14%) and a Pyramimonas strain with high...

2009-01-01

388

Screening for depression with the Patient Health Questionnaire-2 (PHQ-2) among the general population in Hong Kong  

British Library Electronic Table of Contents (United Kingdom)

Background: This study investigates the psychometric properties of the Patient Health Questionnaire-2 (PHQ-2) in the general population of Hong Kong. Methods: Random sampling was used to recruit 6028 participants aged 15years or over. Among them, 203 were surveyed twice within a two-week period. Participants completed the Chinese version of the PHQ-9 (including 2 items of the PHQ-2), the Chinese Health Questionnaire, the Happiness Scale, the SF-12, and questions about diagnosis and health service utilization. Internal consistency, test-retest reliability, construct and discriminant validity of the PHQ-2 were assessed. Results: Cronbach's a was 0.76. The test-retest reliability over two weeks calculated by intraclass correlation was 0.70. Spearman correlation results showed that the PHQ-2 s...

2011-01-01

389

Science, security and spies  

British Library Electronic Table of Contents (United Kingdom)

The national research and development (R&D) base has in the post-cold war era gained increased importance in order to fill new security demands. There is a broadening of the search for security relevant science and technology involving more organizations and interests, scientific disciplines and nations. The question discussed in this article is if the premises of international, free and open R&D will be(come) compromised? Will we see more scientists, in their normal scientific activities, being accused of spying? The article suggests that such risks are not unrealistic to expect. Spy cases in less democratic countries could have consequences for scientists also in other countries. Outcomes depend on, among other things, the relative strengths of academic freedom and a political ...

2009-01-01

390

Science and Society: Integrity and honesty in research  

CERN Document Server

Results that contradict known physics, data manipulated, lack of vigilance by co-authors, failures in the system for scientific publication... Last September a US Committee of Enquiry unveiled one of the most serious frauds in the history of physics. Over a two year period, a young researcher at Bell Laboratories had published a large number of articles with exciting results for solid state physics, but which, alas, were fraudulent! Obviously a fraud of this magnitude is exceptional. However, it did serve to focus attention on the problem of integrity and honesty in research practices. This subject, crucial to the well-being and credibility of scientific research, will be the central theme of the lecture given by Nicholas Steneck, Professor of History at the University of Michigan. A leading expert on this issue, on which he has published extensively, he is a consultant to the Office of Research Integrity in the US, and has been closely involved in public policy-making in relation to ...

2003-01-01

391

Roles and challenges of the health information management educator: a national HIM faculty survey.  

Science.gov (United States)

Health information technology initiatives created the framework for a national health information infrastructure that concomitantly fostered a need to build intellectual capacity within our current and future health information management (HIM) work force. Results from the 2008 HIM Educator Survey are discussed. Developed for voluntary electronic participation, the survey comprised a series of questions about educators' professional interests and responsibilities. Summary data from the 402 respondents are provided and highlight areas such as academic rank, teaching status, salary range, levels of interest in various issues, and use of virtual learning tools. Data from this survey provide insights into the concerns and challenges many HIM educators face in today's training institutions and suggest implications for future directions in work force training and professional development within the HIM field. PMID:19424453

2009-04-30

392

Risk trade-off linked to temporary storage function in road transports  

British Library Electronic Table of Contents (United Kingdom)

Today?s demand on high supply chain performance requires higher awareness about supply chain risks and uncertainty. The purpose of this paper is to analyse the role of temporary storage in the transport network in a supply chain perspective. The primary research question concerns the purpose or role of temporary storage and whether management of temporary storage can contribute to reducing risks and uncertainty in the supply chain. The research is based on a system-theoretical approach, which emphasizes a holistic view instead of the characteristics of the different parts. The research method used in this paper is abductive. Existing theories are used to formulate a framework which leads to a conceptual model description of the temporary storage function. This model is then supported and v...

2011-01-01

393

Retrospective investigation of sudden maternal weight loss as an indicator of impending parturition in the term gravida: A pilot study  

British Library Electronic Table of Contents (United Kingdom)

Summary The aim of the study was to perform a retrospective review of records to test a possible significant association between sudden, modest weight loss (t-test and Wilcoxon test p values were 0.95 and 0.61, respectively. A Kolmogorov-?Smirnov test p value was 0.2139. A one-half standard deviation difference in time to delivery, approximately 2.5 days, was detectable with 0.95 probability. It was concluded that these data may be the first time this question has been investigated and provide evidence that sudden, modest weight loss at the end of pregnancy is not associated with shorter time to onset of natural labour.

2011-01-01

394

Relationships of the Lateral Femoral Cutaneous Nerve to Bony Landmarks  

British Library Electronic Table of Contents (United Kingdom)

Background The lateral femoral cutaneous nerve (LFCN) can be at risk during, for example, the insertion of pins in the anterior superior iliac spine (ASIS) during external fixation of the pelvis, total hip arthroplasty through a direct anterior approach, open surgery for impingement in the hip through an anterior approach, and periacetabular osteotomy. During surgery, the surgeon usually assumes the location of the LFCN by using the ASIS as a landmark. Questions/purposes We investigated (1) whether there is any relationship between the LFCN and the ASIS and (2) the anatomy of the LFCN at the lateral border of the psoas major. Methods Using 25 formalin-fixed cadavers, we determined the location of the LFCN emergence point as above, same level with, or below the iliac crest (IC). We measured...

2011-01-01

395

Regulation of natural gas: policy and politics, 1938-1978  

Energy Technology Data Exchange (ETDEWEB)

The history of the political process surrounding regulations is traced from the 1930s, when the natural gas industry and the Federal Power Commission were in their infancy. The author traces the changing mandate that Congress has provided the regulators and the instincts for self-preservation that these bureaucrats have manifested when they suspected a change in presidential administration or a new decision from the Supreme Court. Natural gas has been one political issue that has split Congress by region. The economic interests of producer and consumer states have often been at such odds that regulation has involved the question of redistribution of wealth among regions as well as between households and industry. The picture is complicated by the link between gas production and distribution and the production and distribution of coal and oil. 12 figures, 25 tables.

1981-01-01

396

Reflexive polytopes of higher index and the number 12  

CERN Document Server

We introduce reflexive polytopes of index l as a natural generalisation of the notion of a reflexive polytope of index 1. These l-reflexive polytopes also appear as dual pairs. In dimension two we show that they arise from reflexive polygons via a change of the underlying lattice. This allows us to efficiently classify all isomorphism classes of l-reflexive polygons up to index 200. As another application, we show that any reflexive polygon of arbitrary index satisfies the famous "number 12" property. This is a new, infinite class of lattice polygons possessing this property, and extends the previously known sixteen instances. The number 12 property also holds more generally for l-reflexive non-convex or self-intersecting polygonal loops. We conclude by discussing higher-dimensional examples and open questions.

2011-01-01

397

Recriticality of a BWR core during reflood after control blade meltdown  

Energy Technology Data Exchange (ETDEWEB)

In nuclear reactor safety research, the question of the possible consequences of delayed core reflood during severe accidents or anticipated transient without scram transients in boiling water reactors (BWRs) has been raised. One can envisage a very low probability accident scenario leading to core uncovery and core heat-up, followed by control blade melting and subsequential delayed reflooding of the core with unborated water before its degradation. Reflooding of the hot core causes significant increases in the peak heating, melting, and hydrogen production rates, thus increasing the probability of core degradation. However, as has been established, debris beds formed from shattered fuel rods and quenched fuel melt will be undermoderated. The reflood process of a voided, intact core was examined using the TRAC/BFI CODE.

1994-12-31

398

Rb-Sr isotopic studies on granodioritic rocks from the Mecsek mountains, Hungary  

Energy Technology Data Exchange (ETDEWEB)

New isotopic age determinations carried out with the rubidium-strontium method on granodioritic basement rocks from the Mecsek Mountains in Southeastern Transdanubia give further support to assumptions on a polyphase development of the Mecsek crystalline. As shown by initial Sr isotopic ratios, the protolith of the granodioritic assemblage of polymetamorphic-anatectic origin must have been strongly basic in its composition. The scatter of individual model ages obtained on total rock samples reflects the polymetamorphic-polytectonized character of the basement, and suggests that following a primary granitization process secondary events might have led to the total or partial recrystallization of the rocks in question. The tectonic development of the basement crystalline as reflected in the isotopic age data closed at about 270+-20 million years ago, with processes causing retrograde changes in the crystalline as a whole but leading to the development of dyke rocks ...

1981-01-01

399

Radon concentration measurements at water reservoirs  

International Nuclear Information System (INIS)

Ground water is treated in the Czech Republic so that small water tanks are built above each water source to serve the primary ground water treatment; water so pretreated is then concentrated in large basins for subsequent treatment. Some water tanks where the first contact of the ground water with air takes place were selected as sites predisposed to radon accumulation. The examination was carried out near the town of Jihlava, where the bedrock contains slightly elevated radium concentrations. The average radon concentrations lay within the region of 2-4 kBq/m"3; the instantaneous values, however, exhibited appreciable periodical variations during the day. The relatively high radon concentrations will not pose a marked hazard for the personnel because the employees only reside at the sites in question for 10 to 15 minutes within 2 days, not for the whole working day

1998-09-09

400

Radiation protection  

International Nuclear Information System (INIS)

The book presents a very good account of all aspects of protection from ionizing radiation. The quantities and units are given and defined used in nuclear physics and dosimetry. The effects of ionizing radiation on cells and on man are described. The principles are presented of radiation protection including limits and valid regulations and decrees. Also discussed is internal irradiation and its modelling. A great part of the book is devoted to aspects of monitoring persons, the living and working environment and to the determination of internal contamination. The system of radiation protection in Czechoslovakia is described and some practical questions are discussed of protection during radiodiagnosis and radiotherapy, in the nuclear fuel cycle, in the operation of nuclear power installations and in crack detection. In conclusion a survey is given of the population exposure from various natural and artificial sources. (M.D.). 57 figs., 34 tabs., 138 refs.

1988-01-01

401

RESRAD model presentation  

Energy Technology Data Exchange (ETDEWEB)

RESRAD was one of the multimedia models selected by the US Nuclear Regulatory Commission (NRC) to include in its workshop on radiation dose modeling and demonstration of compliance with the radiological criteria for license termination. This paper is a summary of the presentation made at the workshop and focuses on the 10 questions the NRC distributed to all participants prior to the workshop. The code selection criteria, which were solicited by the NRC, for demonstrating compliance with the license termination rule are also included. Among the RESRAD family of codes, RESRAD and RESRAD-BUILD are designed for evaluating radiological contamination in soils and in buildings. Many documents have been published to support the use of these codes. This paper focuses on these two codes. The pathways considered, the databases and parameters used, quality control and quality assurance, benchmarking, verification and validation of these codes, and capabilities as well as ...

1998-05-01

402

Quantum coherence in ion channels: resonances, transport and verification  

Energy Technology Data Exchange (ETDEWEB)

Recently it was demonstrated that long-lived quantum coherence exists during excitation energy transport in photosynthesis. It is a valid question up to which length, time and mass scales quantum coherence may extend, how one may detect this coherence and what, if any, role it plays in the dynamics of the system. Here we suggest that the selectivity filter of ion channels may exhibit quantum coherence, which might be relevant for the process of ion selectivity and conduction. We show that quantum resonances could provide an alternative approach to ultrafast two-dimensional (2D) spectroscopy to probe these quantum coherences. We demonstrate that the emergence of resonances in the conduction of ion channels that are modulated periodically by time-dependent external electric fields can serve as signatures of quantum coherence in such a system. Assessments of experimental feasibility and specific paths towards the experimental realization of such experiments are ...

2010-08-15

403

Probing Student Understanding of Scientific Thinking in the Context of Introductory Astrophysics  

Science.gov (United States)

Common forms of testing of student understanding of science content can be misleading about their understanding of the nature of scientific thinking. Observational astronomy integrated with related ideas of force and motion is a rich context to explore the correlation between student content knowledge and student understanding of the scientific thinking about that content. In this paper, we describe this correlation in detail with a focus on a question about the relative motion of the Sun and the Earth. We find that high achieving high school students throughout New York City struggle with what constitutes scientific justification and thought processes, but can improve these skills tremendously in an inquiry-oriented summer astronomy-physics program. (Contains 3 tables and 4 figures.)

2008-12-01

404

Predicting urban forest growth and its impact on residential landscape water demand in a semiarid urban environment  

British Library Electronic Table of Contents (United Kingdom)

We present an innovative approach to estimating residential irrigation water demand for a large metropolitan area using GIS data, weather station data, and a water budget modeling approach commonly used by plant scientists and landscape management professionals. An important question addressed by our study is how a growing urban forest affects the overall irrigation water demand of a semiarid metropolitan area. To estimate the amount of water required by residential landscaping, we consider water demand to be a function of the areal extent of residential landscaping (i.e. tree/shrub or turf grass), the water-loss rate for different landscaping types, the efficiency with which the landscape is irrigated, and local climatic factors (i.e. reference evapotranspiration and precipitation). We es...

2011-01-01

405

Photovoltaic performance and long-term stability of dye-sensitized mesoscopic solar cells  

International Nuclear Information System (INIS)

The efficiency of electric power generation by dye-sensitized mesoscopic photovoltaic cells has been progressing steadily over the last years reaching now 11% in full sunlight. An important question for practical applications concerns the stability of these devices under prolonged exposure to light or heat. Strikingly stable operation can be obtained by judicious selection of the sensitizer, electrolyte and sealant rendering feasible a service life of at least 20 years under normal outdoor conditions. The sensitizer playing a central role in the light energy conversion process, we analyze the kinetic requirements for it to sustain the required one hundred million turnovers. We also review recent results on the use of self-assembled monolayers of amphiphilic sensitizers and co-adsorbents to enhance the thermal robustness of the device. (author)

2004-07-04

406

On the binding effect of air pollution concentration values of the Technical Code Clean Air (TA Luft) in favor of the plant operator. Zur Bindungswirkung der Emissionswerte der TA Luft zugunsten des Anlagenbetreibers  

Energy Technology Data Exchange (ETDEWEB)

The dogmatic and constitutional basis as well as points of definition concerning the Technical Code Clean Air (TA Luft) are explained at first, followed by an assessment of the air pollution concentrations within the overall complex of the air pollution abatement measures, and an analyses of air pollution concentrations as a concretization of the state-of-the-art. In connection with the differentiation of the various applicability levels of TA Luft, the inhouse validy for authorities, the importance for law courts and, finally, the external binding effect for plant operators and possible third parties are discussed. At the center of attention are questions concerning validity claims and validity possibilities. (HSCH).

1991-01-01

407

On the Robustness of Robustness Checks of the Environmental Kuznets Curve Hypothesis  

British Library Electronic Table of Contents (United Kingdom)

Since its first inception in the debate on the relationship between environment and growth in 1992, the Environmental Kuznets Curve hypothesis (EKC hereafter) has been subject of continuous and intense scrutiny. The most recent line of investigation criticizes the EKC hypothesis on more fundamental grounds, in that it stresses the lack of sufficient statistical testing of the empirical relationship and questions the very existence of the notion of EKC. Attention is in particular drawn on the stationarity properties of the series involved?per capita emissions or concentrations and per capita GDP?and, in case of presence of unit roots, on the cointegration property that must be present for the EKC to be a well-defined concept. Only at that point can the researcher ask whether the long-run re...

2009-01-01

408

Observation of the study of protein metabolism in relation to nutrition  

International Nuclear Information System (INIS)

It is a useful hypothesis to thing of the reaction to protein deprivation as made up of two parts. First there is an initial adaptation involving rapid losses of protein. This is followed by slow continuing depletion. When considering two organ groups, such as the liver and muscle, it appears that the curve of urinary nitrogen excretion reflects the different parts they play in these two phases. The changes in the relative amounts of protein in different organs results in an alteration in the pattern of body protein at the level of the organ, the tissue and the cell. These changes are themselves the result of altered rates of synthesis and breakdown. The questions that must be asked and hopefully will be answered with the help of isotopes, are how these changes are brought about, how they are inter-related and controlled, and what is their significance? This paper contains a discussion of the few results that have been obtained so far. 1 fig.

1965-06-01

409

Neurotoxicity and bony diseases caused by the continuous contamination with aluminum of solutions of renal dialysis  

International Nuclear Information System (INIS)

This article reviews the principal evidences about aluminum neurotoxicity in vitro, and some evidences in brain tissues of Alzheimer patients; and also show some studies realized with human that suffer renal deficiencies, dealing whit the principal osteodystrophy. The problem of analyzing low aluminum concentration in human fluids is overcome with very sensitive analytical methods as electrothermal atomic absorption spectrometry (ETAS) and voltammetric methods as Anodic Striping Voltammetry with complexing agents that easing adsorption over solid electrodes or mercury hanging drops. Is a vital question to know with accuracy the aluminum concentration in water used in hemodialysis or in fluids used in ambulatory peritoneal dialysis, as a first stage to prevent contamination by aluminum. So the prevention of contamination during sapling storage and analysis of biological fluids should be the first need and the sources of water used in renal dialysis keep be as clean ...

2001-01-01

410

Natural remedy use in a prospective cohort of breast cancer patients in southern Sweden  

British Library Electronic Table of Contents (United Kingdom)

Abstract Background. Complementary and alternative medicine (CAM) use is common among breast cancer patients. Several CAM therapies may have negative side effects or interact with conventional therapies. We studied biologically based CAM use with and without vitamins/minerals in relation to patient and tumor characteristics as well as treatment in an ongoing prospective cohort of 855 primary breast cancer patients. Methods. Patients from two hospitals in southern Sweden were included. Pre-operative and follow-up questionnaires containing questions on food intake, lifestyle, and concomitant medications, including natural remedies, were completed up to five years postoperatively. Clinical information was obtained from clinical records and tumor characteristics from pathology reports. Results...

2011-01-01

411

Narrative medicine and healthcare reform.  

Science.gov (United States)

Narrative medicine is one of medicine's most important internal reforms, and it should be a critical dimension of healthcare debate. Healthcare reform must eventually ask not only how do we pay for healthcare and how do we distribute it, but more fundamentally, what kind of healthcare do we want? It must ask, in short, what are the goals of medicine? Yet, even though narrative medicine is crucial to answering these pivotal and inescapable questions, it is not easy to describe. Many of its core claims go against the grain of common sense thinking about medicine. This article argues that the best way to understand narrative medicine is to tell a story that puts its emergence in historical context. PMID:21053060

2011-03-01

412

Multiple Reggeon exchange from summing QCD Feynman diagrams  

International Nuclear Information System (INIS)

Multiple Reggeon exchange supplies subleading logarithms that may be used to restore unitarity to the Low-Nussinov Pomeron, provided it can be proven that the sum of Feynman diagrams to all orders gives rise to such multiple Regge exchanges. This question cannot be easily tackled in the usual way except for very low-order diagrams, on account of delicate cancellations present in the sum which necessitate individual Feynman diagrams to be computed to subleading orders. Moreover, it is not clear that sums of high-order Feynman diagrams with complicated crisscrossing of lines can lead to factorization implied by the multi-Regge scenario. Both of these difficulties can be overcome by using the recently developed non-Abelian cut diagrams. We are then able to show that the sum of s-channel-ladder diagrams to all orders does lead to such multiple Reggeon exchanges. copyright 1997 The American Physical Society.

413

Multi-level energy analysis of emerging technologies: a case study in new materials for lithium ion batteries  

British Library Electronic Table of Contents (United Kingdom)

A range of new nanomaterials to replace the active materials in lithium ion batteries are currently being studied and employed in an attempt to overcome various performance limitations of previous technologies. Nanomaterial production and manufacturing techniques appear to fit into a general trend towards more energy intensive production methods for high-tech goods. This does not necessarily imply an increase in lifecycle energy use; artefacts that consume or transform energy during use could possibly regain this increased initial input via increased efficiency in use. In particular, this paper highlights that larger gains could be possible if the artefact in question allows a given service to be provided via an alternative and more efficient system entirely.The lifecycle energy efficienci...

2011-01-01

414

Mucosal Inflammation in Spondylarthritides: Past, Present, and Future  

British Library Electronic Table of Contents (United Kingdom)

Spondylarthritides (SpA) and inflammatory bowel disease (IBD) are idiopathic, chronic inflammatory disorders. Although they are very distinct and well-defined entities, there is clinical and genetic evidence supporting some degree of overlap between the pathogenesis of the two. Subclinical gut inflammation is present in up to two thirds of all SpA patients and can evolve into IBD. This subclinical gut inflammation has been shown to be strongly associated with joint inflammation, providing a clue for a common pathophysiologic background. Despite extensive research progress in the field over the past few years, many questions remain unanswered. In this paper, we focus on the clinical, genetic, and pathophysiologic overlap of SpA and IBD. Furthermore, we discuss some of the targets that may i...

2011-01-01

415

Moufang loops that share associator and three quarters of their multiplication tables  

CERN Document Server

Two constructions due to Dr\\'apal produce a group by modifying exactly one quarter of the Cayley table of another group. We present these constructions in a compact way, and generalize them to Moufang loops, using loop extensions. Both constructions preserve associators, the associator subloop, and the nucleus. We conjecture that two Moufang 2-loops of finite order $n$ with equivalent associator can be connected by a series of constructions similar to ours, and offer empirical evidence that this is so for $n=16$, 24, 32; the only interesting cases with $n\\le 32$. We further investigate the way the constructions affect code loops and loops of type $M(G, 2)$. The paper closes with several conjectures and research questions concerning the distance of Moufang loops, classification of small Moufang loops, and generalizations of the two constructions.

2006-01-01

416

Magnetic resonance imaging in joint diseases  

International Nuclear Information System (INIS)

Magnetic resonance imaging has proven an invaluable method in the diagnosis of joint diseases associated with osteonecrotic, inflammatory, traumatic and degenerative processes. At the clinical level, it has an important role in decisions about the method of treatment and evaluations of the therapeutic success. When the merits of MRT are balanced against those of conventional radiography including tomography and CT, which both ensure better spatial resolution in the visualisation of cortical and spongy bone structures, it becomes quite evident that MRT must not be regarded as an alternative method of imaging but as one that can be used additionally to obtain the most information for the diagnosis of arthropathy. The question as to whether new pulse sequences (snap shots) or invasive techniques like intra-articular injection of paramagnetic substances (MR arthrography) are likely to become routine procedures in the detection of joint diseases using MRT remains to be ...

417

MINERGIE modules: heat pump - heat pump/solar - wood - wood/solar; Minergie-Module Waermepumpe - Waermepumpe/Solar - Holz - Holz/Solar  

Energy Technology Data Exchange (ETDEWEB)

This research report for the Swiss Federal Office of Energy (SFOE) presents the results of a project that examined the feasibility of setting up 'MINERGIE' low-energy-consumption module standards for the production of heat in small residential buildings. The aims of the standards and the basic idea behind the MINERGIE-modules are discussed. The concepts of the modules for heat pumps and wood-fired heating systems and their combination with solar installations are examined, as are their areas of application. The requirements placed on the modules are listed. System concepts, including simple schematics for typical installations, are presented for wood-log, wood-chippings and pellets-fired systems as well as for ground-loop and air-water heat pump systems as well as their solar-aided counterparts. The results of cost-benefit analyses are presented and questions regarding system guarantee and liability are examined.

2005-07-01

418

Literary Lives and a Literal Death: Yajnavalkya, Sakalya, and an Upaniṣadic Death Sentence  

British Library Electronic Table of Contents (United Kingdom)

One of the most popular stories found in the Upani?ads centers around a debate between the ritualist and philosopher, Yajnavalkya, and a series of interlocutors about the nature of sacrifice, the self, and the cosmos. This story, from a textual-historical perspective, is unique in that the last interlocutor, Sakalya, is said to die by having his head shatter because he is unable to answer a question about the fundamental nature of immortality. In this paper, I analyze the interrelationship of these two main characters and argue that this relationship is one key to not only understanding the portrayal of these characters, but also the larger import of this debate about immortality. I provide an intratextual rationale for the head-shattering conclusion and discuss how character and d...

2011-01-01

419

Lighting in indoor environments: Visual and non-visual effects of light sources with different spectral power distributions  

British Library Electronic Table of Contents (United Kingdom)

Since the end of the 1990s, good quality lighting was that which balanced the needs of humans, economic and environmental issues, and architectural design. Recent studies aimed to find a correlation between environmental lighting and human performance and health, with positive results. What is known, is that insufficient or inappropriate light exposure can disrupt standard human rhythms which may result in adverse consequences for performance, safety, health. By studying the relationship between human physiology and light, research in photobiology has advanced to the point where some attempts to foresee what the lighting practice will be in future. The question is if lighting practice and lighting practitioners are ready for changes. This paper has the aim of introducing the recent discove...

2011-01-01

420

Liberalization, internationalization, and globalization: charting the course of foreign investment in the finance and commerce of Japan, 1945-2009  

British Library Electronic Table of Contents (United Kingdom)

As the world's largest creditor nation, with some of the world's largest banks and leading industries, Japan is often portrayed as an economic and financial superpower. With long-established 'Western-style' financial institutions to represent it in all the world's major financial capitals and markets, a technologically savvy Japan is often said to be positioning itself to lead Asia, the Asia/Pacific region, or even the entire world, into the marvels of the twenty-first century. Against this continuing rhetorical backdrop, however, fundamental questions arise as to Japan's ability to internationalize in today's increasingly globalized world economy. Domestically, only a very limited presence is permitted to the foreigner in the Japanese economy, especially in the commanding heights of finan...

2010-01-01

421

LITHIUM ABUNDANCES IN RED GIANTS OF M4: EVIDENCE FOR ASYMPTOTIC GIANT BRANCH STAR POLLUTION IN GLOBULAR CLUSTERS?  

International Nuclear Information System (INIS)

The determination of Li and proton-capture element abundances in globular cluster (GC) giants allows us to constrain several key questions on the multiple population scenarios in GCs, from formation and early evolution to pollution and dilution mechanisms. In this Letter, we present our results on Li abundances for a large sample of giants in the intermediate-metallicity GC NGC 6121 (M4), for which Na and O have been already determined by Marino et al. The stars analyzed are both below and above the red giant branch bump luminosity. We found that the first and second generation stars share the same Li content, suggesting that a Li production must have occurred. This provides strong observational evidence supporting the scenario in which asymptotic giant branch stars are GC polluters.

2010-06-20

422

Issues in food irradiation  

International Nuclear Information System (INIS)

This discussion paper has two goals: first, to raise public awareness of food irradiation, an emerging technology in which Canada has the potential to build a new industry, mainly oriented to promising overseas markets; and second, to help build consensus among government and private sector decision makers about what has to be done to realize the domestic and export potential. The following pages discuss the potential of food irradiation; indicate how food is irradiated; outline the uses of food irradiation; examine questions of the safety of the equipment and both the safety and nutritional value of irradiated food; look at international commercial developments; assess the current and emerging domestic scene; and finally, draw some conclusions and offer suggestions for action.

1995-10-01

423

Is exposure to silica associated with lung cancer in the absence of silicosis? A meta-analytical approach to an important public health question  

British Library Electronic Table of Contents (United Kingdom)

Objective This report investigates epidemiologically whether exposure to silica is associated with lung cancer risks in individuals without silicosis. Methods We searched the PubMed reference data base from 1966 through 1/2007 for reports of lung cancer in silica-exposed persons without and with silicosis. To explore heterogeneity between studies, a multi-stage strategy was employed. First, fixed-effect summaries (FES) and corresponding 95% confidence intervals (CI) for various combinations of studies were calculated, weighting individual results by their precision. The homogeneity of the contributing results was examined using ?2 statistics. Where there was evidence of substantial heterogeneity, the CI around the FES was increased to take account of the between-study variability. Random-e...

2009-01-01

424

Interconnected project 'Development and testing of a biological monitoring for effects of polycyclic aromatic hydrocarbons on man'  

International Nuclear Information System (INIS)

The research project had the aim to develop a standard for measuring individual, inner stresses from polycyclic aromatic hydrocarbons (PAHs) at work. The employed method was by characterizing PAHs and metabolites of PAHs to be identified in urine with a view to developing a biological monitoring of professionally exposured persons. Using a number of PAHs relevant to work, the following questions were studied in cell culture systems and different animal-experimental models: Which metabolites are formed from the PAHs used in cell culture systems and the different animal-experimental models, and what are their ratios in percent? What percentage of a PAH is excreted by experimental animals in their urine and faeces on the first, second, and third day following different forms of application? What is the scale of the individual range of variation of PAH mass excretion? Are these results transferable to man? (orig.).

1992-01-01

425

Integration of Tissue-engineered Cartilage With Host Cartilage: An In Vitro Model  

British Library Electronic Table of Contents (United Kingdom)

Background We developed a tissue-engineered biphasic cartilage bone substitute construct which has been shown to integrate with host cartilage and differs from autologous osteochondral transfer in which integration with host cartilage does not occur. Questions/purposes (1) Develop a reproducible in vitro model to study the mechanisms regulating tissue-engineered cartilage integration with host cartilage, (2) compare the integrative properties of tissue-engineered cartilage with autologous cartilage and (3) determine if chondrocytes from the in-vitro formed cartilage migrate across the integration site. Methods A biphasic construct was placed into host bovine osteochondral explant and cultured for up to 8 weeks (n?=?6 at each time point). Autologous osteochondral implants served as controls...

2011-01-01

426

Informing the decision makers on the cost and value of green building  

Energy Technology Data Exchange (ETDEWEB)

This paper seeks to challenge the traditional way in which we assess the value of green buildings in terms of their environmental friendliness, energy efficiency and whole life cost. In the UK, quantity surveyors (or cost consultants) have a perception that more energy efficient and environmentally friendly buildings cost between 5% and 15% more to build from the outset. This common assumption is not backed up by recent research and should be questioned. Construction professionals need to be informed of the whole life cost and environmental impact of buildings so that they can encourage key stakeholders to make more sustainable choices. These emerging issues together with practical tools are considered with case studies from recent projects. (Author)

2000-09-01

427

Improving Commitment to Basic Education for the Minorities in Botswana: A Challenge for Policy and Practice  

Science.gov (United States)

This paper is part of a study that assessed the level of commitment of primary schools of remote area dwellers (RADs) to basic education between October 2004 and April 2005. The research question focused on the level of commitment of schools to universal basic education, school-community partnership in school governance and parental involvement in the way the curriculum was delivered. Questionnaire and interviews were used. The results show a significant relationship between teachers' perceptions and variables such as district, qualifications, age, location, and experience. There is consistency between teachers' perceptions and children's academic performance. It has been found that learner achievement in RADs schools is low and that parents are not actively involved in their children's education due to the policy environment and school management practices.

2008-07-01

428

Improvement of reproducibility and sensitivity of CE analysis by using the capillary coated dynamically with carboxymethyl chitosan  

British Library Electronic Table of Contents (United Kingdom)

Analysis reproducibility and detection sensitivity of capillary electrophoresis (CE) are often questioned by applied scientists, which has hindered its application as a routine method. To address these issues, a simple, precise, and reproducible dynamic coating method was developed by applying carboxymethyl chitosan (CMC) dynamic coating on fused silica capillary. The proposed coating was accomplished by simply rinsing the capillary with CMC solution for 1?min in between runs, with no regeneration procedure or buffer additives needed. Electroosmotic flow could be well controlled by adjusting the pH of background electrolyte, and the adsorption of analytes onto the capillary inner wall was effectively eliminated. The main parameters of the coating condition were optimized, and extensive app...

2011-01-01

429

Implementing 10 CFR Part 830 Subpart B at WIPP  

Energy Technology Data Exchange (ETDEWEB)

Implementation of Title 10 Code of Federal Regulations Part 830, Subpart B Nuclear Safety Management (1) was accomplished at the Waste Isolation Pilot Plant (WIPP) in a timely and efficient manner. The primary reason the transition went smoothly was that the existing safety analysis was relatively new, initially developed in 1995, and written in accordance with the safe harbor document DOE-STD-3009 (2). The WIPP Safety Analysis Report (SAR) (3) is kept up-to-date with the unreviewed safety question (USQ) process and thorough oversight and input provided by DOE-Carlsbad Field Office (CBFO) documented in the annual safety evaluation report (SER) process.

2002-02-26

430

Impact of partitioning and transmutation on the high level waste management  

British Library Electronic Table of Contents (United Kingdom)

Nuclear energy generates 30% of the electricity in the EU. Still, different countries of EU27 have very different attitudes towards the future use of nuclear energy for electricity generation or other uses. However, independently of the political decision of continuation or phase out of the nuclear energy, all countries using nuclear energy to generate electricity are facing the question of the final management of its spent nuclear fuel and other high level radioactive wastes. Partition and Transmutation are emerging technologies that when integrated in advanced fuel cycles can strongly influence on the final wastes from the nuclear industry and its management. A review of the progress on the understanding of their real potentialities and main conclusions from a large number of internation...

2011-01-01

431

Impact of ocean pollution  

Energy Technology Data Exchange (ETDEWEB)

Man's wastes are polluting the oceans from various sources and delivered by various routes. The result has been the loss of habitat and the irreversible altering of marine ecosystems. Development in the coastal zones and offshore activities that disrupt biologically sensitive areas have led to international negotiations to regulate these impacts and develop a law of the sea. Basic to international cooperation, however, is the need to develop answers to questions about the ecological consequences of development programs and the carrying capacity of the oceans. Current information does not demonstrate long-term global impacts, making it difficult to detect and predict incremental changes and causal relationships. Society needs to determine how much environmental damage it will accept and then to develop appropriate technology, such as biomonitoring. Society also needs to reexamine its positions on technology-based regulatory controls to see if the effects of ...

1981-03-01

432

Identification of oxidation states of ultra-trace elements by radiation detection  

International Nuclear Information System (INIS)

The determination of the oxidation state of ultra-trace elements in the environment, especially in the case of actinides, is of importance in many ways. Speciation techniques using radiation may comprise methods based on the detection of the nuclear and atomic radiations emitted in radioactive decay or methods using external sources of excitation. In the former instance, information can be obtained from the energy and intensity of radiation, but at present the partition method is still the most commonly used, although its reliability is questionable. Excitation with intense laser beams, as is currently being used for trace element analysis in photoacoustic and thermal lensing spectroscopic techniques, could conceivably be applied under suitable conditions to ultra-trace elements with a sensitivity approaching that of the radiochemical methods.

1989-11-01

433

Hydrostatic extrusion of magnesium: process mechanics and performance  

Energy Technology Data Exchange (ETDEWEB)

Following the breakthrough for cast magnesium products, interest is now spreading to wrought applications - triggering a variety of technological questions. A major bottleneck in the manufacture of magnesium sections (profiles) by conventional hot extrusion is the low productivity, with extrusion speeds typically five to ten times lower than for comparable aluminium sections. This paper focuses on the use of hydrostatic extrusion as a means to overcome this problem. On the basis of an analytical model, it is clarified why and how process limits are affected by the process mechanics. Experimental work on the hydrostatic extrusion of the alloys M1A, ZM21 and AZ31 confirms that extrusion speed is indeed multiplied, whereas the resulting mechanical properties are similar to or better than those for conventional extrusions. (orig.)

2003-07-01

434

Human brain development in infants with PET and FDG  

International Nuclear Information System (INIS)

The authors used studies of local cerebral metabolic rate for glucose (LCMRGlc) to examine development of cerebral organization in 5 days to 1 year old children. A group (n=8) of infants with diverse pediatric disorders allowed investigation of developmental changes in LCMRGlc, while also providing relevant clinical management information. Patients consisted of questionable and definite neonatal seizures, cerebral embolism from cardiac sources, and otherwise normal infants with facial nevi with consideration of Sturge-Weber. Gradual increase in cortical LCMRGlc coincides with suppression of intrinsic subcortical reflexes present in all newborns. Two retarded children (2 years old) showed LCMRGlc developmental patterns of a few days old, which corresponded to their functional and mental status. These studies illustrate great potential of PET to study normal and altered states of human brain development.

1985-06-02

435

How is Regeneration of Plants after Mowing Affected by Shoot Size in Two Species-Rich Meadows with Different Water Supply?  

British Library Electronic Table of Contents (United Kingdom)

Mowing a meadow is an example of an equalizing process that reduces differences among species by removing aboveground biomass approximately 5?cm above ground. This regular disturbance that affects all plants prevents competitive exclusion of small species and thus allows coexistence of numerous species differing in shoot size. In this paper we search for the mechanism behind this by comparing the shoot biomass of 41 common species in dry and wet species-rich meadows in mown and recently abandoned plots in June (before mowing) and in October. We asked the following questions: i) Do the plants differ in proportion of biomass lost by mowing? ii) Are the mown plants able to compensate for biomass lost by mowing? iii) Is the compensatory ability of mown plants related to their size? iv) Is the ...

2010-01-01

436

How do mathematicians learn math?: resources and acts for constructing and understanding mathematics  

British Library Electronic Table of Contents (United Kingdom)

In this paper, we present an analytic framework for investigating expert mathematical learning as the process of building a network of mathematical resources by establishing relationships between different components and properties of mathematical ideas. We then use this framework to analyze the reasoning of ten mathematicians and mathematics graduate students that were asked to read and make sense of an unfamiliar, but accessible, mathematical proof in the domain of geometric topology. We find that experts are more likely to refer to definitions when questioning or explaining some aspect of the focal mathematical idea and more likely to refer to specific examples or instantiations when making sense of an unknown aspect of that idea. However, in general, they employ a variety of types of m...

2011-01-01

437

How can supply networks increase firm value? A causal framework to structure the answer  

British Library Electronic Table of Contents (United Kingdom)

The recent literature in the field of supply chain management emphasizes the role of inter-organizational networks and the integration of vertical reproduction networks (supply chains) in particular as a key factor for value creation. However, the literature includes little empirical evidence. This situation suggests the need to appraise investments in such networks or supply chains carefully. How can a decision maker reliably assess the effect of investing in inter-organizational network arrangements on firm value? This article takes up this issue and suggests a framework consisting of five components to help answer the question. The task of the framework is to support the structuring and revelation of the causal chain between investments in the network on the one hand and the effect of t...

2009-01-01

438

How Do Police Respond to Stalking? An Examination of the Risk Management Strategies and Tactics Used in a Specialized Anti-Stalking Law Enforcement Unit  

British Library Electronic Table of Contents (United Kingdom)

How do police respond to and manage complaints of stalking? To answer this question, we conducted a 3-phase study. First, we reviewed the literature to identify risk management tactics used to combat stalking. Second, we asked a group of police officers to review those tactics for completeness and group them into categories reflecting more general risk management strategies. The result was 22 categories of strategies. Finally, we used qualitative methods to evaluate the files of 32 cases referred to the specialized anti-stalking unit of a metropolitan police department. We coded specific risk management tactics and strategies used by police. Results indicated that a median number of 19 specific tactics from 7 general strategies were used to manage risk. Also, the implementation of strategi...

2011-01-01

439

Heapable Sequences and Subsequences  

CERN Document Server

Let us call a sequence of numbers heapable if they can be sequentially inserted to form a binary tree with the heap property, where each insertion subsequent to the first occurs at a leaf of the tree, i.e. below a previously placed number. In this paper we consider a variety of problems related to heapable sequences and subsequences that do not appear to have been studied previously. Our motivation for introducing these concepts is two-fold. First, such problems correspond to natural extensions of the well-known secretary problem for hiring an organization with a hierarchical structure. Second, from a purely combinatorial perspective, our problems are interesting variations on similar longest increasing subsequence problems, a problem paradigm that has led to many deep mathematical connections. We provide several basic results. We obtain an efficient algorithm for determining the heapability of a sequence, and also prove that the question of whether a sequence can ...

2010-01-01

440

HOW IS THE ETHICS OF STEM CELL RESEARCH DIFFERENT FROM THE ETHICS OF ABORTION?:  

British Library Electronic Table of Contents (United Kingdom)

Abstract: It seems that if abortion is permissible, then stem cell research must be as well: it involves the death of a less significant thing (an embryo rather than a fetus) for a greater good (lives saved rather than nine months of physical imposition avoided). However, I argue in this essay that this natural thought is mistaken. In particular, on the assumption that embryos and fetuses have the full moral status of persons, abortion is permissible but one form of stem cell research is not-the practice of creating embryos and then destroying them to extract cell material. Furthermore, I argue that the same is true on the assumption that embryos and fetuses have at least some moral status. I conclude that this form of stem cell research is permissible only if the embryos in question lack ...

2007-01-01

441

Extragalactic Planetary Nebulae: Observational Challenges & Future Prospects  

CERN Document Server

The study of extragalactic planetary nebulae (EPN) is a rapidly expanding field. The advent of powerful new instrumentation such as the PN spectrograph has led to an avalanche of new EPN discoveries both within and between galaxies. We now have thousands of EPN detections in a heterogeneous selection of nearby galaxies and their local environments, dwarfing the combined galactic detection efforts of the last century. Key scientific motivations driving this rapid growth in EPN research and discovery have been the use of the PNLF as a standard candle, as dynamical tracers of their host galaxies and dark matter and as probes of Galactic evolution. This is coupled with the basic utility of PN as laboratories of nebula physics and the consequent comparison with theory where population differences, abundance variations and star formation history within and between stellar systems informs both stellar and galactic evolution. Here we pose some of the burning questions, ...

2004-01-01

442

Estrogen and raloxifene improve metaphyseal fracture healing in the early phase of osteoporosis. A new fracture-healing model at the tibia in rat  

British Library Electronic Table of Contents (United Kingdom)

Background Fracture healing in osteoporosis is delayed. Quality and speed of fracture healing in osteoporotic fractures are crucial with regard to the outcome of patients. The question arises whether established antiosteoporotic drugs can further improve fracture healing. Materials and methods Osteoporosis manifests predominantly in the metaphyseal bone. Nevertheless, an established metaphyseal fracture model is lacking. A standardized metaphyseal fracture-healing model with stable plate fixation was developed for rat tibiae. The healing process was analyzed by biomechanical, gene expression, and histomorphometric methods in ovariectomized (OVX) and sham-operated rats (SHAM), compared to standardized estrogen (E)- and raloxifene (R)-supplemented diets. Results Estrogen and raloxifene impro...

2010-01-01

443

Epidemiology of exposure to electromagnetic fields: An overview of the recent literature. (Reannouncement with new availability information)  

Energy Technology Data Exchange (ETDEWEB)

Increased concern about potential health problems related to exposure to nonionizing electromagnetic fields (EMF) has occurred recently. The most recent epidemiological studies have dealt mainly with effects of extremely low frequency EMF on fetal development and cancer. This paper summarizes noteworthy aspects or recent reviews and studies in this area of research. There has been increased concern recently about potential health problems related to exposure to nonionizing electromagnetic fields (EMF). Although some questions have been raised concerning exposure to radiofrequency radiation (at frequencies up to 300 GHz), the major focus has been on fields of extremely low frequency (especially 60 Hz). The most recent epidemiologic studies have dealt mainly with effects of extremely-low-frequency EMF on fetal development and with the initiation or promotion of cancer.

1991-12-31

444

Emerging global divides in media and communication theory: European universalism versus non-Western reactions  

British Library Electronic Table of Contents (United Kingdom)

What Wallerstein described as European universalism dominated media and communication theory until the end of the twentieth century. The three-tier divide of the global economic system (center, semi-periphery, and periphery) explicated in world-system analysis was equally applicable to the global academic/scholarship structure. The non-traditional fields of study, such as media and (mass) communication, inherited the full flavor of European universalism because they originated in the academic institutions of the center countries. The turn of the century saw a dramatic reaction to the Euro-American rhetoric of power. Organized groups of scholars have begun to question the presumption of European universalism in media and communication theory, encompassing its axiology, epistemology/methodol...

2009-01-01

445

Electricity line construction without participation of the municipalities. Stromleitungsbau ohne Beteiligung der Gemeinden  

Energy Technology Data Exchange (ETDEWEB)

The contribution examines whether the construction of high-voltage transmission lines without formal participation of local authorities is permissible. In this connection the question is also treated to what extent municipal co-determination in transmission line construction represents a precondition for the permissibility of compulsory purchase measures. The individual issues treated are: the formal legal situation and current practice in the construction of electricity pylons; individual legal protection in connection with compulsory purchase; the construction of pylons without a construction licence as an infringement of the municipal right to self-government of local authorities; and the effects on the execution of compulsory purchase procedures of the illegality under Building Law of pylons constructed without approval. (RST).

1990-03-15

446

Effective Population Size Is Positively Correlated with Levels of Adaptive Divergence among Annual Sunflowers  

British Library Electronic Table of Contents (United Kingdom)

The role of adaptation in the divergence of lineages has long been a central question in evolutionary biology, and as multilocus sequence data sets have become available for a wide range of taxa, empirical estimates of levels of adaptive molecular evolution are increasingly common. Estimates vary widely among taxa, with high levels of adaptive evolution in Drosophila, bacteria, and viruses but very little evidence of widespread adaptive evolution in hominids. Although estimates in plants are more limited, some recent work has suggested that rates of adaptive evolution in a range of plant taxa are surprisingly low and that there is little association between adaptive evolution and effective population size in contrast to patterns seen in other taxa. Here, we analyze data from 35 loci for si...

2011-01-01

447

EPRI-USDOE COOPERATIVE AGREEMENT: COFIRING BIOMASS WITH COAL  

Energy Technology Data Exchange (ETDEWEB)

The entire Electric Power Research Institute (EPRI) cofiring program has been in existence of some 9 years. This report presents a summary of the major elements of that program, focusing upon the following questions: (1) In pursuit of increased use of renewable energy in the US economy, why was electricity generation considered the most promising target, and why was cofiring pursued as the most effective near-term technology to use in broadening the use of biomass within the electricity generating arena? (2) What were the unique accomplishments of EPRI before the development of the Cooperative Agreement, which made developing the partnership with EPRI a highly cost-effective approach for USDOE? (3) What were the key accomplishments of the Cooperative Agreement in the development and execution of test and demonstration programs-accomplishments which significantly furthered the process of commercializing cofiring?

2001-09-01

448

Dynamic model based on general input-output analyses - an energy model for the Federal Republic of Germany. Ein dynamisches Modell des allgemeinen Gleichgewichts als Energiemodell fuer die Bundesrepublik Deutschland  

Energy Technology Data Exchange (ETDEWEB)

The study abstracted aims at analyzing the economic effects of energy policies using simulations. Emphasis is on assessing the effects of decisions in favour of an expanding electric power industry based on nuclear energy and hard coal. The study discusses alternative assumptions concerning the cost involved, pollution abatement measures, shutdown and dismantling costs etc. Input-output analyses make the simulation model a consistent vehicle. Besides, the model in question is characterized by its explaining the investment demand of the different sectors by referring to the continuous annual development of innovative technologies.

1986-01-01

449

Does the online channel pay? A comparison of online versus offline information search on physical store spend  

British Library Electronic Table of Contents (United Kingdom)

The Internet has transformed consumer behaviour, particularly the manner in which consumers search for information prior to making a purchase. However, we know relatively little about the relationship between consumer information search strategies prior to visiting a physical retail store and the amount of money spent on product purchases. This raises an important question for retailers; does the online channel pay? We test this notion in a study of 1275 consumers across the four retail categories of Clothing and Footwear, Beauty and Skincare, DIY Hardware, and Kitchen and Bathroom Renovations. We find that in all categories, except for Clothing and Footwear, consumers who used the Internet to search for product information prior to making a physical store purchase, spent more money when p...

2010-01-01

450

Do Higher Hospital-wide Nurse Staffing Levels Reduce In-hospital Mortality in Elderly Patients with Hip Fractures: A Pilot Study  

British Library Electronic Table of Contents (United Kingdom)

Background There is increasing recognition that lower nurse staffing levels are associated with higher morbidity and mortality among medical and surgical patients. The degree to which this applies to elderly patients with hip fractures is unclear. Questions/purposes We conducted a pilot study using administrative data as an initial step in investigating the relationship between nurse staffing levels and in-hospital mortality among elderly patients with hip fractures. Patients and Methods We retrospectively reviewed administrative data for 13,343 patients 65?years or older with a primary diagnosis of hip fracture admitted to 39 Michigan hospitals between 2003 and 2006. We used logistic regression to calculate the change in predicted probability of in-hospital death conferred by differences ...

2011-01-01

451

Do Estrogen and Alendronate Improve Metaphyseal Fracture Healing When Applied as Osteoporosis Prophylaxis?  

British Library Electronic Table of Contents (United Kingdom)

Osteoporosis is accompanied by predominantly metaphyseal fractures with a delayed and qualitatively reduced healing process. This study addressed the question of whether fracture healing in the context of osteoporosis prophylaxis is improved with estrogen (E) or alendronate (ALN). Thirty-six ovariectomized and 12 sham-operated 12-week-old rats received soy-free (osteoporotic C, sham), E-, or ALN- supplemented diets. After 10?weeks, a metaphyseal tibia osteotomy and standardized T-plate fixation were performed. After a 5-week healing process, the fracture callus was evaluated qualitatively by biomechanical bending test and quantitatively in microradiographic sections. The time course of callus formation was examined using fluorochrome-labeled histological sections. Administration of E impro...

2010-01-01

452

Distributed delays stabilize neural feedback systems  

CERN Document Server

We consider the effect of distributed delays in neural feedback systems. The avian optic tectum is reciprocally connected with the nucleus isthmi. Extracellular stimulation combined with intracellular recordings reveal a range of signal delays from 4 to 9 ms between isthmotectal elements. This observation together with prior mathematical analysis concerning the influence of a delay distribution on system dynamics raises the question whether a broad delay distribution can impact the dynamics of neural feedback loops. For a system of reciprocally connected model neurons, we found that distributed delays enhance system stability in the following sense. With increased distribution of delays, the system converges faster to a fixed point and converges slower toward a limit cycle. Further, the introduction of distributed delays leads to an increased range of the average delay value for which the system's equilibrium point is stable. The enhancement of stability with ...

2007-01-01

453

Design creativity: static or dynamic capability?  

British Library Electronic Table of Contents (United Kingdom)

Purpose - Viewing creativity through the theoretical lens of the resource-based view, the paper attempts to answer a fundamental question: is design creativity a static or dynamic capability? If static, then firms need to acquire personnel who are already creative. If dynamic, then personnel's creative talents should be developed through training. Design/methodology/approach - In an exploratory controlled experiment of 74 design engineers from ten firms, two forms of training emphasizing design creativity as static or dynamic capability were applied. Creative designs developed by the participants were judged by professionals inside each organization. Results were analyzed using structural equation modeling. Findings - The exploratory findings support the notion that design creativity is a ...

2008-01-01

454

Degradation Improves Tissue Formation in (Un)Loaded Chondrocyte-laden Hydrogels  

British Library Electronic Table of Contents (United Kingdom)

Background Photopolymerizable poly(ethylene glycol) (PEG) hydrogels offer a platform to deliver cells in vivo and support three-dimensional cell culture but should be designed to degrade in sync with neotissue development and endure the physiologic environment. Questions/purposes We asked whether (1) incorporation of degradation into PEG hydrogels facilitates tissue development comprised of essential cartilage macromolecules; (2) with early loading before pericellular matrix formation, the duration of load affects matrix production; and (3) dynamic loading in general influences macroscopic tissue development. Methods Primary bovine chondrocytes were encapsulated in hydrogels (n?=?3 for each condition). The independent variables were hydrogel degradation (nondegrading PEG and degrading olig...

2011-01-01

455

Creativity and integrity: Marketing the "in development" screenplay  

British Library Electronic Table of Contents (United Kingdom)

This studys purpose was to explore the relationship between creativity and integrity in the ideation phase of feature filmmaking. Integrity refers to ones self-defined ability to maintain authenticity and moral autonomy while preserving ones sense of membership and loyalty to the team or organization. When team members choose elements for the screenplays story that they feel will attract the ideal audience, the dynamic tension between creativity and integrity is most apparent. The forces at play during this phase of work yielded the research question: In what ways and to what degree do screenwriters andor studio executives feel their personal integrity is in alignment with the creative process of feature film development? Several concepts from the literature formed the design around which ...

2009-01-01

456

Cosmological model selection  

CERN Document Server

Model selection aims to determine which theoretical models are most plausible given some data, without necessarily asking about the preferred values of the model parameters. A common model selection question is to ask when new data require introduction of an additional parameter, describing a newly-discovered physical effect. We review several model selection statistics, and then focus on use of the Bayesian evidence, which implements the usual Bayesian analysis framework at the level of models rather than parameters. We describe our CosmoNest code, which is the first computationally-efficient implementation of Bayesian model selection in a cosmological context. We apply it to recent WMAP satellite data, examining the need for a perturbation spectral index differing from the scale-invariant (Harrison-Zel'dovich) case.

2006-01-01

457

Cosmological Questions for the European Southern Observatory Very Large Telescope  

CERN Document Server

The next decade promises an observational revolution which will change cosmology forever. The precise measurement of the angular anisotropy of the cosmic microwave background should specify to a few percent all of the parameters of the cosmological model which effect astrophysics. The growth of structure will then be determined (but not yet observed) until gravitational collapse becomes highly non-linear and stars, galaxies and active galactic nuclei (AGN) form. These processes are hard to model with basic physics because they are complex and allow a rich variety of expression. Instead observations will determine when the first stars and quasars formed, and how and when galaxies assembled. If we can reconcile the numerous contradictions which characterize the subject today, cosmology will become a mature subject, founded on the agreement between detailed, inclusive and realistic models, which make precise predictions, and the wealth of new data which will come from a wide variety of ...

1996-01-01

458

Correlation between the Individual and the Combined Width of the Six Maxillary Anterior Teeth  

British Library Electronic Table of Contents (United Kingdom)

ABSTRACT Purpose: There is a consensus in the community of dental research that the selection of undersized artificial maxillary anterior teeth offers an unnatural appearance to the denture. Several methods to select the adequate width of these teeth are of questionable validity, and many dentures have an obviously artificial appearance. This article assessed the relationship between the individual and the combined width of maxillary anterior teeth. Materials and Methods: Impressions were made of the anterior dentition of 69 dentate undergraduate students with rubber impression silicon, and casts were formed. The individual widths of the maxillary anterior teeth were measured by using a digital caliper (SC-6 digital caliper, Mitutoyo Corporation, Tokyo, Japan), and the combined width was r...

2009-01-01

459

Convergent Flows: Humanities Scholars and Their Interactions with Electronic Texts  

Science.gov (United States)

This article reports research findings related to converging formats, media, practices, and ideas in the process of academics' interaction with electronic texts during a research project. The findings are part of the results of a study that explored interactions of scholars in literary and historical studies with electronic texts as primary materials. Electronic texts were perceived by the study participants as fluid entities because the electronic environment promotes seamless interactions with a variety of media and formats. Working with electronic texts combines some traditional information and research practices into new patterns of information behavior. The practice called "netchaining" combines aspects of networking with information-seeking practices to establish and shape online information chains, which link sources and people. Different forms of exploration of participants' research questions were enabled by interactions with electronic texts.

2008-07-01

460

Cluster Geometry & Inclinations from Deprojection Uncertainties  

CERN Document Server

{The determination of cluster masses is a complex problem that would be aided by information about the cluster shape and orientation (along the line-of-sight).} {It is in this context, that we have developed a scheme for identifying the intrinsic morphology and inclination of a cluster, by looking for the signature of the true cluster characteristics in the inter-comparison of the different deprojected emissivity profiles (that all project to the same X-ray brightness distribution) and by using SZe data when available.} {We deproject the cluster X-ray surface brightness profile under the assumptions of four different geometry and inclination configurations for the observed system; these 4 configurations correspond to four extreme geometry+inclination scenarios. The deprojection in question is performed by the non-parametric algorithm DOPING. The formalism is tested with model systems and then is applied to a sample of 24 clusters. While the shape determination is ...

2008-01-01

461

Ceramic Materials and Devices  

Science.gov (United States)

Course website from Cambridge on ceramic materials. This site contains eight lectures in PDF format (Adobe Reader required), two question sheets, five practicals (including answers), digital movies and further useful links. "There is a strong relationship between the structure of a material and its physical properties. The properties of a material whether mechanical, electrical, optical or magnetic, determine how it can be used in practical applications. In this course, the focus is on the structure / property relationship for ionic materials with electrical properties utilised in various transducer devices. The materials considered include perovskites, which have special polarisation properties exploited in ferroelectric, pyroelectric and piezoelectric devices. Other oxides, such as zirconia, have structures permitting rapid diffusion of ions, making them suitable for use in sensors, fuel cells and batteries. The scientific principles underlying the properties of ...

2007-02-01

462

Cast in Plastic: Semiotic Plasticity and the Pragmatic Reading of Darwin  

British Library Electronic Table of Contents (United Kingdom)

As Darwin portended but failed to develop, and of which Gould made much, the forensic evidence of evolution points toward Punctuated Equilibrium rather than Phyletic Gradualism; however Gould?s empirical postulation has long suffered from its lack of a testable theoretical basis. This is rectified by the work of Jaroslav Flegr and the Frozen Plasticity Theory, a hypothesis with striking application within semiotic theory and hence to questions of epistemology and ontology. The consequences of applying FPT within Biosemiotics is this: when any particular sign carries a great range of interpretation (semiotic polymorphism) combined with a high degree of mutually supportive referencing (semiotic pleiotropy), that sign is less likely to exhibit plasticity?less able to find new expressions capa...

2011-01-01

463

Can the new distribution businesses deliver?  

Energy Technology Data Exchange (ETDEWEB)

In this paper, the question of whether the new distribution system for the electricity supply industry can deliver a better service to customers, is discussed. In particular it discusses the requirement of customers for low cost and efficiency, with particular reference to Victoria in general and Solaris in particular. Solaris comprises the amalgamation of five ex-Municipal Electricity Undertakings and one distribution part of the former State Electricity Commission. Despite not having a set of objectives, a strategy, a common culture, appropriate processes or systems, key account management skills, marketing and customer service expertise, commercial financial expertise, commercial treasury expertise and strategic skill, it has been able to develop a business plan and strategy to satisfy the shareholder (the government), improve customer communication facilities, set up human resource management mechanisms and liaison with the community. The conclusion is that the ...

1995-12-31

464

Beyond the tropics: forest structure in a temperate forest mapped plot  

British Library Electronic Table of Contents (United Kingdom)

Abstract Question: How do the diversity, size structure, and spatial pattern of woody species in a temperate (Mediterranean climate) forest compare to temperate and tropical forests? Location: Mixed evergreen coastal forest in the Santa Cruz Mountains, California, USA. Methods: We mapped, tagged, identified, and measured all woody stems (?1 cm diameter) in a 6-ha forest plot, following Center for Tropical Forest Science protocols. We compared patterns to those found in 14 tropical and 12 temperate forest plots. Results: The forest is dominated by Douglas-fir (Pseudotsuga menziesii) and three species of Fagaceae (Quercus agrifolia, Q. parvula var. shrevei, and Lithocarpus densiflorus), and includes 31 woody species and 8180 individuals. Much of the diversity was in small-diameter shrubs,...

2010-01-01

465

Basic Properties Of Second Smarandache Bol Loops  

CERN Document Server

The pair $(G_H,\\cdot)$ is called a special loop if $(G,\\cdot)$ is a loop with an arbitrary subloop $(H,\\cdot)$. A special loop $(G_H,\\cdot)$ is called a second Smarandache Bol loop(S$_{2^{{\\tiny\\textrm{nd}}}}$BL) if and only if it obeys the second Smarandache Bol identity $(xs\\cdot z)s=x(sz\\cdot s)$ for all $x,z$ in $G$ and $s$ in $H$. The popularly known and well studied class of loops called Bol loops fall into this class and so S$_{2^{{\\tiny\\textrm{nd}}}}$BLs generalize Bol loops. The basic properties of S$_{2^{{\\tiny\\textrm{nd}}}}$BLs are studied. These properties are all Smarandache in nature. The results in this work generalize the basic properties of Bol loops, found in the Ph.D. thesis of D. A. Robinson. Some questions for further studies are raised.

2010-01-01

466

Base flow hydrology and water quality of an Ozarks spring and associated recharge area, southern Missouri, USA  

British Library Electronic Table of Contents (United Kingdom)

Human activities in the karst Ozark Plateaus can impact water quality of springs where surface water is rapidly transferred to subsurface conduits. Bennett Spring, in southern Missouri, is the fourth largest spring in the state and supports local tourism activities. Questions regarding poorly functioning on-site wastewater systems (OWS) have raised concerns over the long-term water quality of the spring. This study reports the results of a surface water quality monitoring program in the recharge area where monthly samples were collected at base flow to identify potential pollution sources to the spring. Base flow hydrology of the recharge area was highly variable over the study period, which was drier than normal, causing an incomplete sampling record due to no flow conditions at some site...

2011-01-01

467

An enhanced model framework of personalized material flow services  

British Library Electronic Table of Contents (United Kingdom)

A growing concern about the consumer behavior in Internet economy has spurred the study of Material Flow, resulting in a unique type of consumer behavioral analysis. This research proposes an enhanced conceptual model for Personalized Material Flow Services for consumer behavior. In the era of Internet information technology, customer?s taste tends to be personalized for their market demand. It is observed that there are number of ?Long Tail? phenomena in several successful e-commerce business cases. However, the Long Tail phenomenon is an open question for our research in terms of its role in e-commerce marketing. In the proposed model-X-Party Personalized Material Flow Services, three elements are discussed. They are ?providing?, ?locating? and ?obtaining? based on X-Party Material Flow ...

2011-01-01

468

Algorithms for Internal Validation Clustering Measures in the Post Genomic Era  

CERN Document Server

Inferring cluster structure in microarray datasets is a fundamental task for the -omic sciences. A fundamental question in Statistics, Data Analysis and Classification, is the prediction of the number of clusters in a dataset, usually established via internal validation measures. Despite the wealth of internal measures available in the literature, new ones have been recently proposed, some of them specifically for microarray data. In this dissertation, a study of internal validation measures is given, paying particular attention to the stability based ones. Indeed, this class of measures is particularly prominent and promising in order to have a reliable estimate the number of clusters in a dataset. For those measures, a new general algorithmic paradigm is proposed here that highlights the richness of measures in this class and accounts for the ones already available in the literature. Moreover, some of the most representative validation measures are also ...

2011-01-01

469

Advancing High-Quality Literacy Research in Juvenile Justice: Methodological and Practical Considerations  

Science.gov (United States)

Special education researchers have made noteworthy progress toward conceptualizing literacy research questions, designing quality studies, and disseminating the results of their research. These advancements have been made through the establishment and refinement of quality research indicators. Unfortunately, this progress has mostly eluded the arena of juvenile justice special education research. The purpose of this article is to review juvenile justice literacy studies and provide juvenile justice personnel and researchers with methodological and practical considerations for improving the quality of juvenile justice literacy research. The focus is on advancing group designs. Practical concerns are based on the first-year experiences of researchers who implemented an Institute of Education Sciences Goal 3 study with the aim of determining the efficacy of literacy instructional programs in a juvenile justice setting.

2010-11-01

470

A.C.R.O. activity report 2000; A.C.R.O. rapport d'activite 2000  

Energy Technology Data Exchange (ETDEWEB)

Environmental surveillance and public information are translated in 2000 by numerous actions. To improve the public information, A.C.R.O. concerns its main efforts on the development of the consumer technical information available on-line via its web site and in its regular publication 'the nuclear chronicle'. A new publication, the A.C.R.O. journal is made to answer to more acute questions as waste burying. Besides, the participation of the A.C.R.O. at various local commissions of information (C.L.I.) as well as at the superior council of the safety and nuclear information ( C.S.S.I.N.) stays an essential action. (N.C.)

2000-07-01

471

A study of binary mixture boiling: boiling site density and subcooled heat transfer  

Energy Technology Data Exchange (ETDEWEB)

(Boiling site densities and heat-transfer coefficients have been measured for ethanol-water and ethanol-benzene mixtures at 1.01 bar for a heated vertical brass disk. A strong effect of composition on the boiling site density was observed, which was attributed to the nature of the activation of the boiling surface and mass diffusion effects. The boiling heat-transfer coefficient was found to decrease with increasin subcooling, but for the mixtures at a given level of subcooling the decrease was less than that for the single components and azeotropic mixtures.) The heat-transfer coefficient at a given heat flux was seen to be quite insensitive to the very large increase in boiling site density in comparing the pure water and the ethanol-water azeotrope results, leading one to question pool boiling models that predict heat-transfer rates on the basis of boiling site density.

1985-05-01

472

A review of the structural characteristics of alloy 800  

International Nuclear Information System (INIS)

The published literature is reviewed and supplemented by current information from the author's laboratory, to show the influence of various compositional, heat treatment and thermomechanical factors on the structural characteristics of Alloy 800. The features discussed include carbon, aluminium, titanium and boron, solution treatment, ageing treatments with and without applied strain, and cold working. Examples of the aspects reviewed include the effect of heat treatment and service or testing temperature on the austenite grain size, and the relative importance of M_2_3C_6 and TiC, the influence of carbon level on gamma prime, the effect of residual or steady stress combined with time at temperature on changes in carbide or gamma prime morphology, and on the appearance of sigma or other intermetallic phases. The questions posed by these features are discussed generally, in terms of their effect on the mechanical properties at ambient and elevated temperatures and ...

473

A model of a self-oscillatory process involving elements discretely distributed in space  

Science.gov (United States)

Self-excited oscillations of a distributed medium can be investigated in terms of discrete physical models described by multidimensional systems of nonlinear equations which transform into equations of self-oscillating distributed media as the number of dimensions goes to infinity. Differential equations of such a self-oscillating system are set up and investigated. Coupling between elements of the medium, conditions under which the system constitutes an open system, internal impedance between the energy source and the system elements, and boundary conditions defining open and closed systems are discussed. The Gunn effect, eolian noise, self-oscillations of DNA molecules and of cardiac muscle, and wave processes in the cerebral cortex are mentioned as examples of self-oscillatory processes in question.

1975-01-01

474

A complete census of AGN and their hosts from optical surveys?  

CERN Document Server

Large optical surveys provide an unprecedented census of galaxies in the local Universe, forming an invaluable framework into which more detailed studies of objects can be placed. But how useful are optical surveys for understanding the co-evolution of black holes and galaxies, given their limited wavelength coverage, selection criteria, and depth? In this conference paper I present work-in-progress comparing optical and mid-IR diagnostics of three "unusual" low redshift populations (luminous Seyferts, dusty Balmer-strong AGN, ULIRGs) with a set of ordinary star-forming galaxies from the SDSS. I address the questions: How well do the mid-infrared and optical diagnostics of star formation and AGN strength agree? To what extent do optical surveys allow us to include extreme, dusty, morphologically disturbed galaxies in our "complete" census of black hole-galaxy co-evolution?

2010-01-01

475

1 The German National Analysis Facility as a tool for ATLAS analyses  

CERN Document Server

In 2008 the German National Analysis Facility (NAF) at DESY was established. It is attached to and builds on top of DESY Grid infrastructure. The facility is designed to provide the best possible analysis infrastructure for high energy particle physics of the ATLAS, CMS, LHCb and ILC experiments. The Grid and local infrastructure of the NAF is reviewed with a focus on the ATLAS part. Both parts include large scale storage and a batch system. Emphasis is put on ATLAS specific customisation and utilisation of the NAF. This refers not only to the NAF components but also to the di erent components of the ATLAS analysis framework. Experience from operating and supporting ATLAS users on the NAF is presented in this paper. The ATLAS usage of the di erent components are shown including some typical use cases of user analysis. Finally, the question is addressed, if the design of the NAF meets the ATLAS expectations for effcient data analysis in the era of LHC data taking.

2011-01-01

476

'Outsiderness' and 'insiderness' in a Confucian society: complexity of contexts  

British Library Electronic Table of Contents (United Kingdom)

This paper addresses the influence of CHC on how the insider/outsider distinction is drawn and what consequences follow for the conduct of research. The paper outlines the methodological complexities faced by us whilst conducting our respective research projects in Hong Kong. In the studies reported in this paper we, the researchers, were insiders at one level as both of us have a degree of familiarity with Hong Kong being residents of the city. We were also insiders on a professional level in the contexts under study. However being ethnically non-Chinese positioned us as outsiders. Additionally, our Western-trained research selves accepted certain normative paradigms, whilst our own personal ethno-centricities tended to question these self-same paradigms. In sum, the research context for ...

2011-01-01

477

Valuing future citizens' values regarding risk  

Energy Technology Data Exchange (ETDEWEB)

Valuing present citizen's values regarding the risks they face is an important aspect of risk assessment and risk acceptability. Conferences like VALDOR are held for this reason. Governments like Sweden have national referendums on various risk-prone enterprises. The results of these referendums can determine the future of these programs. In the United States, when guidelines are set for determining acceptable levels of risk, the relevant federal agencies are often required to provide a comment period regarding proposed guidelines in order to ascertain the judgments, including the weights place on certain values, of individual members of society as well as stakeholder groups. After the comment period ends, the agency decides on the acceptable level of risk, taking into account the comments from present citizens. Do we also have a duty to value the not-yet-existing values of future citizens, especially if the risks created by the activities of present citizens extend into the ...

2006-09-15

478

PKU-RBRC Workshop on Transverse Spin  

Energy Technology Data Exchange (ETDEWEB)

Understanding the structure of the nucleon is a fundamental question in subatomic physics, and it has been under intensive investigation for the last several years. Modern research focuses in particular on the spin structure of the nucleon. Experimental and theoretical investigations worldwide over the last few decades have established that, contrary to nave quark model expectations, quarks carry only about 30% of the totd spin of the proton. The origin of the remaining spin is the key question in current hadronic physics and also the major driving forces for the current and future experiments, such as RHIC and CEBAF in US, JPARC in Japan, COMPASS at CERN in Europe, FAIR at GSI in Germany. Among these studies, the transverse-spin physics develops actively and rapidly in the last few years. Recent studies reveal that transverse-spin physics is closely related to many fundamental properties of the QCD dynamics such as the factorization, the ...

2008-06-30

479

Helical CT defecography  

International Nuclear Information System (INIS)

The purpose of this work is to investigate the possible role of Helical CT defecography in pelvic floor disorders by comparing the results of the investigations with those of conventional defecography. The series analyzed consisted of 90 patients, namely 62 women and 28 men, ranging in age 24-82 years. They were all submitted to conventional defecography, and 18 questionable cases were also studied with Helical CT defecography. The conventional examination was performed during the 4 standard phases of resting, squeezing, Valsalva and straining; it is used a remote-control unit. The parameters for Helical CT defecography were: 5 mm beam collimation, pitch 2, 120 KV, 250 m As and 18-20 degrees gantry inclination to acquire coronal images of the pelvic floor. The rectal ampulla was distended with a bolus of 300 mL nonionic iodinated contrast agent (dilution: 3g/cc). The patient wore a napkin and was seated on the table, except for those who could not hold the position ...

1999-11-01

480

Extension of ASME VIII Division 1 design limits  

Energy Technology Data Exchange (ETDEWEB)

ASME Subcommittee 2 on materials presented a series of questions to PVRC regarding the acceptability of using the criteria of ASME Section 2, Part D, Appendix 1 for extending design limits for AISI 304 stainless steel beyond 1,500 F to 2,000 F and Alloy 800 HT from 1,650 F to 1,800 F respectively. This paper describes a project supported by PVRC to try and find an answer to this question. The project consisted of three parts. The first was a survey to determine the intent behind the wording of the ASME criteria in order to make an extrapolation of methods for setting design limits to higher temperatures. The second was a demonstration of a methodology for developing very high temperature limits, using a set of creep data for Alloy 800 HT. The third was a parametric study to evaluate the feasibility of using the minimum creep rate based deformation criterion used in the ASME Code to set strain related limits on materials showing predominantly ...

1995-12-01

481

Dayside auroral activity and magnetospheric boundary layer phenomena  

Energy Technology Data Exchange (ETDEWEB)

Selected case studies of auroral structure/activity observed at different local times on the dayside are presented and discussed in the context of electrodynamic coupling between the different magnetospheric boundary regions and the ionosphere. The first case addresses the question of the auroral signatures of the two boundary regions referred to as cusp and cleft/LLBL. Combined ground-based and satellite data reveal the different latitudinal zones of auroral forms/particle precipitation/field-aligned current and the relationship with the respective magnetospheric plasma populations, i.e. CPS, BPS, LLBL, and the plasma mantle. Midday auroral breakup events and the related ionospheric ion drift and magnetic observations show many of the features that have been predicted to be ionospheric signatures of flux transfer events. An alternative explanation that has been proposed by others, i.e. ionospheric effect of magnetopause perturbations excited by dynamic pressure ...

1990-07-01

482

[Energy education exhibits for Insights El Paso Science Museum  

Energy Technology Data Exchange (ETDEWEB)

The grant in question, DE-FG03-94ER75954, was awarded to Insights El Paso Science Museum to build key exhibits. These exhibits helped the Museum fulfill its mission to ``promote curiosity and stimulate interest by exploratory, entertaining, exciting, and participatory learning in a broad range of scientific disciplines to persons of all ages regionally and internationally.`` There are several current Board of Directors members who also were Board members during the grant period and who helped construct some of the exhibits. Through speaking with them and reviewing minutes of Board meetings during 1994, it has been determined that seven of the ten proposed exhibits were constructed, with an eighth exhibit constructed as an alternative. Photos of seven of the exhibits and preliminary sketches of some are attached. Following is a list of the constructed exhibits: Hot or Cold, Give and Take, Conduction, Convection, Sources of Energy, Wind Generator, Solar Tracker, and ...

1998-05-27

483

Variable-speed generation enhances hydro operation  

Energy Technology Data Exchange (ETDEWEB)

Two major developments have given impetus to wider adoption of variable-speed turbine/generators in hydroelectric plants, both essentially environmental: (1) the need for stream-bed stability below river dams, and (2) the need to minimize fish damage. Also, the need to stabilize pumped-storage and generating efficiencies to match extreme changes in head levels has been a driving force. Variable-speed operation in hydro applications is relatively new to North America. In other parts of the world, it has been used in pumped-storage plants since 1971. In the US, and increasing potential exists for variable-speed hydro, considering the 30 pumped-storage plants already in operation and several river plants struggling with high head fluctuations--including four at stations operated by the Bonneville Power Administration. Several modifications to hydro-plant hardware and operating procedures are actively being considered at Bonneville--all of them practical but costly. The ...

1993-07-01

484

Two science communities and coastal wetlands policy  

Energy Technology Data Exchange (ETDEWEB)

This study compares the attitudes of academic and government wetlands scientists about wetlands science and policy. Analysis of one thousand seven hundred responses to Delphi-type questions posed to twenty California scientists on a wide range of issues about California coastal wetlands found significant differences between academic and government scientists about wetlands definitions, threats to wetlands, wetlands policies, wetlands health, and wetlands mitigation strategies. These differences were consistent with descriptive models of political sociology developed by D. Price and C.P. Snow and with normative models of the philosophy of science developed in the renaissance by F. Bacon and R. Descartes. Characteristics, preferences, and personality attributes consistent with group functions and roles have been described in these models. These findings have serious implications for policy. When academic and government wetlands scientists act as advisors to the major ...

1984-01-01

485

The influence of metallurgical variables on the temperature dependence of irradiation hardening in pressure vessel steels  

International Nuclear Information System (INIS)

Yield stress elevations (#DELTA##sigma#_y) in pressure vessel steels irradiated at intermediate flux and fluence systematically decreased with increasing temperature and decreasing copper and nickel content. Lower stress relief temperature also decreased #DELTA##sigma#_y at bulk copper concentrations greater than about 0.3%. The dependence of #DELTA##sigma#_y on irradiation temperature between 260 and 316 C increased with copper and nickel content and decreased with phosphorus content. When normalized by the average #DELTA##sigma#_y, the fractional temperature dependence correlates with a simple empirical chemistry factor of copper and phosphorus. The correlation predicts data on the irradiation temperature dependence of #DELTA##sigma#_y found in the literature within a standard error of about 0.3 MPa/degree C and is consistent with current understanding of hardening mechanisms. However, questions remain about the effects at very low flux and finer scale variations ...

1994-06-20

486

Tar protocol. Development of a standard method for the measurement of organic contaminants ('Tar') in biomass producer gases  

Energy Technology Data Exchange (ETDEWEB)

This paper presents the history and objectives of the development of a standard method for the measurement of organic contaminants in biomass producer gases. Recently, a project with that title has started in the European 5{sup th} Framework Programme. The structure of this project with acronym 'Tar Protocol' is also described in this paper. The project is performed by 17 partners and continues earlier work initiated by IEA (International Energy Agency), DoE (Department of Energy) and EU (European Union) in 1998. The project aims to combine two draft Protocols that resulted from this earlier work. The Tar Protocol will be developed for accurate measurement of organic contaminants ('tars') over a large range of concentrations (1 mg/Nm{sup 3} to 100 g/Nm{sup 3}) and conditions (0 - 900 deg C; 0.9 - 60 bars). Besides, a particulate concentration will be determined too. Together with the Protocol comes a number of accepted 'shortcut' ...

2000-06-01

487

Somatostatin receptor scintigraphy might be useful for detecting skeleton abnormalities in patients with multiple myeloma and plasmacytoma  

International Nuclear Information System (INIS)

Somatostatin receptor expression has been demonstrated on a number of plasma cell lines. Therefore, we questioned whether somatostatin receptor scintigraphy (SRS) can be used to demonstrate in vivo multiple myeloma (MM) activity. SRS was performed in newly diagnosed (n = 9) or relapsing (n = 18) MM patients or in patients with localized plasmacytoma (n = 2). The results were compared with radiographic findings. A positive SRS was demonstrated in 44% of the newly diagnosed patients, in 83% of the relapsed patients and in both patients with plasmacytoma. The SRS findings corresponded with radiographic abnormalities in 40% of the patients. However, in relapsed patients 60% demonstrated increased SRS uptake in areas without new radiographic abnormalities. The positive SRS corresponded with histologically proven disease activity and responded upon treatment. Moreover, immunohistochemical staining of MM material demonstrated concordant somatostatin receptor sst3 staining ...

2010-01-01

488

Respect distances. Rationale and means of computation  

Energy Technology Data Exchange (ETDEWEB)

Canisters with spent nuclear fuel can obviously not be located within deformation zones as this might jeopardise their long term mechanical stability and thereby constitute a potential hazard to the biosphere. Less apparent, but equally important, is the fact that earthquakes trigger reactivation, slip, of structures some distance from their hypocentres due to, among many other factors, stress redistribution. Fault slip across a deposition hole might damage the isolation capacity of the canister and thereby jeopardise the overall integrity of the barrier system. Therefore, the following question might be posed: What is the distance from a deformation zone beyond which a canister can be safely emplaced? This respect distance cannot be readily computed because, unknown future events aside, there are some complicated aspects that need to be addressed e.g. degree of conservatism, scale, our ability to model ice sheets and earthquakes, etc. In this report we discuss ...

2004-12-01

489

Resolving the Pu Electronic Structure Enigma: Past Lessons and Future Directions  

Energy Technology Data Exchange (ETDEWEB)

The nature of the 5f electronic structure of plutonium (Pu) remains unclear. [1] Despite many recent attempts to resolve the issue, a plethora of important unanswered questions remain. While many theoretical approaches to the problem have been promulgated, the real source of the difficulty is the absence of sufficient experimental benchmarking. This paucity of impact on the part of experimental results is driven in part by the difficulties of working with Pu: it is highly radioactive, biologically toxic, chemically reactive and restricted in its distribution and permitted access to user facilities. The results of these liabilities include the following: (1) it is very difficult, if not impossible, to get large single crystals of single phase samples and; (2) many state of the art experiments can not be done because general user facilities are not available for use with Pu samples. Additionally, there is the apparently bizarre nature of Pu, which seems to defeat the ...

2008-05-30

490

Magnetic resonance imaging in multiple sclerosis. Imagerie nouvelle par resonance magnetique nucleaire au cours de la sclerose en plaques  

Energy Technology Data Exchange (ETDEWEB)

Magnetic resonance imaging (MRI) has rapidly attained a major position among the examinations used in the diagnostic approach of multiple sclerosis because it is highly sensitive in demonstrating lesions. However, these lesional images may have several meanings, and there is the problem of distinguishing between oedema, which is said to reflect recent lesions, and gliosis which is thought to betray old lesions. The intrinsic MRI parameters studied (i.e. relaxation times) are unable to make this distinction, whereas it is provided by paramagnetic contrast media such as gadolinium. There is no correlation between the changes observed at MRI and the severity of the disease. Another problem is the accuracy of lesion localization, since visualization is predominantly macroscopic. This raises several questions about the demonstration of correlations between clinical signs and site of the lesion(s). At the moment, several teams of neuroradiologists are trying to find the ...

1991-09-15

491

Long term durability and performance of radon mitigation subslab depressurization systems  

International Nuclear Information System (INIS)

Subslab depressurization (SSD) systems have become the most popular radon mitigation technique used by professional mitigators. Readily available supplies and equipment from other trades are commonly utilized in the installation of these systems. What is not currently known is the long-term performance of some of the caulks or sealants and the mechanical devices such as fans or controls. The operating environment for the fans is often different from that for which they were designed. Specifically, this involves studying whether the fans are still operating as installed, whether there has been an increase or decrease in the radon levels after several years of operation, and whether the homeowners are operating the systems the way the systems were originally designed. To answer these questions, the authors have tested eight of the Piedmont Study homes as well as homes in which post-mitigation measurements done by New Jersey Dept. of Environmental Protection have ...

1990-02-19

492

Generational Structure of Models with Dynamical Symmetry Breaking  

CERN Document Server

In models with dynamical electroweak symmetry breaking, this breaking is normally communicated to quarks and leptons by a set of vector bosons with masses generated via sequential breaking of a larger gauge symmetry. In reasonably ultraviolet-complete theories of this type, the number of stages of breaking of the larger gauge symmetry is usually equal to the observed number of quark and lepton generations, $N_{gen.}=3$. Here we investigate the general question of how the construction and properties of these models depend on $N_{gen.}$, regarded as a variable. We build and analyze models with illustrative values of $N_{gen.}$ different from 3 (namely, $N_{gen.}=1,2,4$) that exhibit the necessary sequential symmetry breaking down to a strongly coupled sector that dynamically breaks electroweak symmetry. Our results for variable $N_{gen.}$ show that one can robustly obtain, for this latter sector, a theory with a gauge coupling that is large but slowly running, ...

2010-01-01

493

Evaluating created wetlands through comparisons with natural wetlands  

Energy Technology Data Exchange (ETDEWEB)

The report summarizes the evaluation and recommendations regarding an approach to wetland sampling and characterization developed by the Wetlands Research Program (WRP) at U.S. Environmental Protection Agency, Environmental Research Laboratory, Corvallis, OR. Between trials, team members discussed at length the methodology and field protocols and modified them to reflect the conditions and difficulties encountered in sampling herbaceous wetlands in urban areas of Florida. Major emphasis is placed on the appropriateness of measured variables for determining successful wetland re-creation. Numerous physical and biological parameters were measured and compared in the nine created and nine natural wetlands. Analysis of these data has shown some important similarities and differences between created and natural wetlands and lends insight into the complex questions surrounding wetland creation and the equivalency of created wetlands to naturally occurring wetlands. ...

1991-11-01

494

Elective ilioingunial lymph node irradiation  

International Nuclear Information System (INIS)

Most radiologists accept that modest doses of irradiation (4500-5000 rad/4 1/2-5 weeks) can control subclinical regional lymph node metastases from squamous cell carcinomas of the head and neck and adenocarcinomas of the breast. There have been few reports concerning elective irradiation of the ilioinguinal region. Between October 1964 and March 1980, 91 patients whose primary cancers placed the ilioinguinal lymph nodes at risk received elective irradiation at the University of Florida. Included are patients with cancers of the vulva, penis, urethra, anus and lower anal canal, and cervix or vaginal cancers that involved the distal one-third of the vagina. In 81 patients, both inguinal areas were clinically negative; in 10 patients, one inguinal area was positive and the other negative by clinical examination. The single significant complication was a bilateral femoral neck fracture. The inguinal areas of four patients developed mild to moderate fibrosis. One patient with moderate ...

495

Carbonate shoreline sedimentation in San Andres Formation, Lincoln County, New Mexico  

Energy Technology Data Exchange (ETDEWEB)

The Permian San Andres Formation of late Leonardian-early Guadalupian age is a significant hydrocarbon producer and crops out over a large area in south-central New Mexico. However, since its definition in 1909, the age and depositional environment of this unit have been questioned. In 1971 in Pecos County, Vincent Kelly divided the unit into three members: Rio Bonito, Bonney Canyon, and Fourmile Draw. The lowest member, although named for the Rio Bonito, has a type section designated at Sunset along U.S. Highway 70/380. Two miles east of Sunset, near Riverside, on the Rio Bonito, the Rio Bonito Member is exposed in a long series of roadcuts. Petrographic investigation of these rocks reveals an alternating sequence of high to low-energy intertidal to subtidal facies marked by oolitic and fossiliferous dolocalcarenite interbedded with dolomitic mudstone. The unit has been recrystallized and stylolites are abundant, as is dolomite and nodular mosaic anhydrite. These ...

1986-03-01

496

Americans' political participation in the 1993-94 national health care reform debate.  

Science.gov (United States)

The health politics and policy communities are still struggling with the question of "what went wrong" in the 1993-94 health care reform effort. Here I identify which Americans were politically active and inactive during the health care reform debate to explore the role political participation may have had in determining the outcome of the debate. Using data from a national and California random-sample telephone surveys, and controlling for other demographic attributes, I found that those who engaged in political activity specifically related to health care reform were disproportionately more likely to be self-identified conservatives, less likely to favor an employer mandate plan, more likely to be fifty to sixty-four years old, more likely to be men, and more likely to have greater interest in and knowledge of the health care issue. Even in California, where a single-payer proposal was on the November ballot, self-identified liberals were no more likely to engage ...

1996-01-01