BackgroundTo identify the differential tuberculosis (TB) characteristics within the immigrant population with respect to natives in Spain.Methodology/Principal...Full Text Available
Terminal-differential algorithm for identification of local nonhomogeneities in items under control is developed on the basis of measurements of X-ray or gamma-radiation weakening. The algorithm may be applied by developing radiation schemes of nondestructive control, identifying inadmissible inclusions in the object under study
We have identified the nonreceptor tyrosine kinase syk as a marker of differentiation/tumor suppressor in pancreatic ductal adenocarcinoma (PDAC). Syk expression is lost in poorly differentiated PDAC...Full Text Available
Anomalous features in Gulf Coast Salt domes exhibit deviations from normally pure salt and vary widely in form from one dome to the next, ranging considerably in length and width. They have affected both conventional and solution mining in several ways. Gas outbursts, insolubles, and potash (especially carnallite) have led to the breakage of tubing in a number of caverns, and caused irregular shapes of many caverns through preferential leaching. Such anomalous features essentially have limited the lateral extent of conventional mining at several salt mines, and led to accidents and even the closing of several other mines. Such anomalous features, are often aligned in anomalous zones, and appear to be related to diapiric processes of salt dome development. Evidence indicates that anomalous zones are found between salt spines, where the differential salt intrusion accumulates other materials: Anhydrite bands which are ...
An indoor radioactive survey is being conducted in an Italian district. Preliminary results identified a zone with significant radioactive levels, in which a new specific survey has been planned. In this paper attention is dedicated mainly to radon measurement technique and results.
ObjectiveThe objective of this study was to identify patterns of brain activation elicited by erotic visual stimuli in patients treated with either Selective Serotonin Reuptake Inhibitors...Full Text Available
In an earlier report, we used differential cloning to identify genes that might be critical in controlling arterial neointima formation (Giachelli, C., N. Bae, D. Lombardi, M. Majesky, and S. Schwartz....Full Text Available
Fibrogenesis is a common feature of many diseases where there is severe insult to the liver. The hepatic stellate cell trans-differentiation into a myofibroblast has been identified as an important...Full Text Available
Humans are remarkably adept at identifying individuals by the sound of their voice, a behavior supported by the nervous system’s ability to integrate information from voice and speech...Full Text Available
A strain from human diarrhea originally identified as Campylobacter mucosalis (NCTC 12408) was examined by using 64 phenotypic characters. The similarity of this strain to 297 isolates of Campylobacter,...Full Text Available
Purpose : To detect differentially expressed genes in the patients with uterine cervical cancer during the radiation therapy. Materials and Methods : In patients with biopsy proven uterine cervical cancer, we took a tumor tissue just before radiation therapy and at 40 minutes after external irradiation of 1.8 Gy. Total RNAs isolated from non-irradiated and irradiated tumor tissue samples were analyzed using the differential-display reverse transcription-polymerase chain reaction (DDRT-PCR). Complementary DNA (cDNA) fragments corresponding to differentially expressed messenger RNAs(mRNAs) were eluted, and cloned. The differential expression of the corresponding mRNAs was confirmed by reverse northern blot. Differentially expressed cDNA bands were sequenced. Nucleotide sequence data were analyzed in the Gene Bank and EMBL databases via the BLAST network server to ...
This is the introductory paper for eight papers that follow in this issue of Natural Resources Journal that were presented at a symposium on the titled subject. The editor notes that two movements in recent decades have been identified with coastal regions - efforts to conserve natural resources and energy source development - and that profound social, economic, and political ramifications have attended these movements. He further notes that the tensions and demands created by the above two developments proved too much for state and local mechanisms, eventually culminating in the Coastal Zone Management Act of 1972. He then briefly evaluates the focus and success of CZMA and reviews the other papers. 58 references.
The spatial connection between the zones of deep-lying faults and the narrowly-localized paleo-relief sections posessing an anomolous sedimentation condition in the latter Cretaceous is identified. It is established that this is of significance in choosing the primary regions for conducting oil exploration.
The pollution of the aquatic zones grows with the time, principally due to industrial and urban settlements, among others, in the surroundings of these sites. The sources of this pollution can be identified by the study of the characteristics of the sediment, this gives relevant information to evaluate any aquatic system. Once the sediment is obtained, a series of preliminary tests are carry out (loss of ignition, 210{sup P}b dating) to be sure that we have a sedimentary core that hans .t be mixed, once this has be done we determine radionuclides, heavy metals and organic compounds. (Author) 2 refs.
Brain scintiscanning which was first carried out exclusively 'statical' and only with test substances of limited quality has been replaced nowadays by 'dynamical' camera-sequency-scintiscanning with technetium. This brought considerable progress not only for identifying but also for the differential diagnosis of cerebro-organic processes. Development, methods, and integration of brain scintiscanning in a diagnostical conception are described briefly. (orig.).
The authors identify a need for a device which can remotely measure methane in coal mines. Similar techniques which have been used to measure atmospheric pollutants are discussed. These techniques include adsorption, Raman scattering and fluorescence. While differential adsorption and Raman scattering techniques have potential there are a number of problems to be resolved before they could be applied effectively. It is felt that an area which may provide suitable technology sometime in the future is in the field of laser sources. 6 refs., 4 tabs.
We retrospectively studied the computed tomography scans of the orbit in 75 patients in order to identify the presence of incidental calcifications (scleral and trochlear apparatus calcifications.). These imaging findings should integrate the vast list of differential diagnosis of orbital calcifications, as they may help radiologists to distinguish these calcifications from orbital foreign bodies. (author)
Indicators of source water use in different economic branches, water consumption in recycling and recycling-successive water supply in 1980?2006 are analyzed. Trends were identified in variations in specific water consumption in industry, agriculture, and municipal economy. Territorial differentiation of wetness indicators of regional product over federal districts and constituent territories of the RF is shown. Wetness values of gross domestic product in different economies are compared.
This paper studies on the modelling of a butterfly-type control valve actuating by an on-off pneumatic solenoid valve. The mathematical model is composed of nonlinear differential equations three parts: (i) a solenoid valve, (ii) a pneumatic cylinder, (iii) a rotary-type butterfly valve. The flow characteristics of the butterfly control valve is analysed by a computer simulator, then its simple transfer function is identified from the step responses.
Physiological functions are carried out by differentiated cells, with finite lifespans, which age and need to be replaced. In young individuals, tissue functions are sustained at optimal levels because cellular dysfunction and cell loss are balanced by the emergence of newly differentiated cells as stem cells and their partially differentiated descendants replicate. However, with the passage of time the mitotic rates of these cells diminish. Eventually, replications occur too infrequently to offset the loss. It is at this point that the tissue begins to show structural changes and declining function which, as they become pervasive, are identified as ageing. In this paper the theory is set forth that: (1) Diminishing mitotic activity in older tissues results from limited stem cell replicative capacity. (2) All stem cells, regardless of tissue, exhibit similar replicative patterns over time, progressing ...
The epidermal compartment is complex and organized into several strata composed of keratinocytes (KCs), including basal, spinous, granular, and cornified layers. The continuous process of self-renewal and barrier formation is dependent on a homeostatic balance achieved amongst KCs involving proliferation, differentiation, and cell death. To determine genes responsible for initiating and maintaining a cornified epidermis, organotypic cultures comprised entirely of stratified KCs creating epidermal equivalents (EE) were raised from a submerged state to an air/liquid (A/L) interface. Compared to the array profile of submerged cultures containing KCs predominantly in a proliferative (relatively undifferentiated) state, EEs raised to an A/L interface displayed a remarkably consistent and distinct profile of mRNAs. Cultures lifted to an A/L interface triggered the induction of gene groups that regulate proliferation, differentiation, and cell death. ...
The Coastal Zone Sector of the Canadian Climate Impact and Adaptation Research Network (C-CIARN) was established to address concerns regarding climate change in coastal areas. Coastal zones are sensitive to increases in air, sea and ground temperatures as well as to variations in sea level, precipitation, ice thickness, and storm intensity. This report presents the results of a workshop which focused on how coastal communities will be affected by climate induced water level changes, particularly sea-level rise on ocean coasts and decreasing lake levels in the Great Lakes. The workshop addressed issues such as the effects of changing water levels on coastal infrastructure, utilities, community development, and the implications of changing water levels to human safety, cultural resources, tourism, and insurance. The workshop reviewed the current state of understanding on water level fluctuations resulting from climate change. It also ...
There is a plethora of new silver-containing dressings on the market today. Various manufacturers attempt to show that their dressings are the most efficacious and therefore should be preferentially employed by health care workers based on the results of their in vitro tests. However, there have been no studies that clearly identify which tests are appropriate for comparison purposes. The purpose of this study was to determine which in vitro test is most appropriate for evaluating the antimicrobial efficacy of silver-containing dressings. This was done by testing seven silver-containing dressings and two non-silver-containing topical agents against 17 clinically relevant microorganisms using zone of inhibition assays and time-kill kinetic assays in complex media. The results for the two assays were then correlated to determine whether the methods generated similar results. It was determined that the two methods do not correlate at all. This is ...
DescriptionFarm-level estimates of the financial impact of regulation are important indicators of the effect that a regulation have. Such estimates should be included in RIA, particularly within the Small Firms Impact Test. This farm-level analysis can be used in the RIA to inform judgements of the affordability of the regulation proposal. It will help to identify which farm types are likely to be financially had-hit from the regulation. Farm-level cost estimates for each regulation are also required t [continued...
Theoretical description of Raman scattering in disordered alloys of Ti and Zr with transition metals of groups 5-8 of the Mendeleev Periodic System in critical range of concentrations (CRC) is given. Results of Raman scattering experiment in the system Ti_1_-_xF_x at 0.0005identified by previously made Moessbauer measurements for the same samples, are presented. The order of the values of hybridization potential and energy of impurity zone, as well as their concentrational dynamics, are determined. Qualitative adequacy of the hybridization model to the alloys studied near CRC is shown.
Pectin rich cold stored spoiled fruits, vegetables and cold soils were screened and different pectinolytic isolates were obtained by enrichment culturing and ruthenium red plate assay. Among the primary isolates 10-15% were yeast isolates. Six isolates with higher zones of pectin hydrolysis were selected and tested for polygalacturonase (PGU) production at room temperature (25 degrees C) and at 5 degrees C. One isolate identified as Saccharomyces sp. with highest polygalacturonase activity at 5 degrees C was used for enzyme production using raw fruit pectins as substrates. The isolate was identified by preliminary cultural, morphological and sugar fermentation tests. PGU production was high in raw pectin substrates like orange peel (21 U/ml), apple peel (20 U/ml ), mango peel (19 U/ml), ...
The heptageniid mayflies Epeorus latifolium and Epeorus l-nigrus are often the dominant species in the upper and midstream areas of Japanese rivers; as such, they play a significant role in river ecosystems. However, although these two species have been identified using the morphological characteristics of the male in its adult stage, it is impossible to differentiate them in their nymphal stage. We conducted a study to elucidate their distribution pattern, i.e., the current distribution of these two species in the Shinano-gawa River basin, based on quantitative field sampling and genetic analysis of nymphs and also some male adults; for these, it was possible to differentiate between the two species reliably. The data collected from the 30 study sites of the 1-year-long study revealed tha...
This study was conducted to investigate the antibacterial effect of BSAP-254 on Bacillus cereus with the induced stress proteins. The BSAP-254 is an antimicrobial peptide isolated from soybean-fermenting bacteria, Bacillus subtilis SC-8. It had a narrow spectrum of activity against B. cereus group. The growth inhibitory effect of BSAP-254 (50??g/mL) reduced the population of B. cereus from >108 to 104 colony-forming units per milliliter within 30?min. In B. cereus exposed to BSAP-254, 14 intracellular proteins were differentially expressed as determined by 2-DE coupled with MS. Of the differentially expressed proteins identified, the stress protein GroEL, which is heat shock protein, was induced in B. cereus exposed to antibacterial peptide.
Objective: Atherosclerosis is an inflammatory disease, modulated by plaque stabilizing and de-stabilizing cell populations such as infiltrating monocytes and vascular smooth muscle cells (vSMCs). Transcription factors regulating proliferation and differentiation of atherosclerosis relevant cell types are of interest in this context. The forkhead box transcription factor FoxP1 modulates monocyte differentiation. We studied FoxP1 expression in atherosclerotic tissue, correlated FoxP1 expression with plaque characteristics and identified associations between FoxP1 and plaque proteins. Methods: 116 Atherosclerotic plaques from carotid endarterectomy samples were histologically classified (fibrous, fibroatheromatous, atheromatous) and subjected to semi-quantitative protein analysis. Macrophage,...
Erythroid differentiation regulator (Erdr1) was first discovered in mouse leukemia cell lines and functions as a stress-related survival factor. This study investigated whether Erdr1 regulates murine melanoma progression, as well as the mechanism involved in Erdr1-regulated metastasis. The expression of Erdr1 is negatively correlated with IL-18 expression, which has a pro-cancer effect in melanoma. To study the role of Erdr1 as an anti-cancer factor, cell migration, invasion, and proliferation were measured. Erdr1 overexpression markedly inhibited the level of cell migration, invasion, and proliferation in B16F10 cells in vitro. In addition, Erdr1 overexpression significantly suppressed melanoma lung colonization, metastasis, and tumor growth in vivo. To identify the factors involved in Er...
To increase further the accuracy of flow regime and considering the non-stationary characteristics of differential pressure fluctuation signals of gas-liquid two-phase flow, the flow regime identification method based on recurrence quantification analysis (RQA) and multi-sensor data fusion techniques is put forward. First of all, the recurrence quantification analysis method is used to extract the nonlinear feature parameters of the differential pressure fluctuation signals of gas-liquid two-phase flow, and data fusion of feature layer is conducted by QRA feature parameters of differential pressure signals of three pressure measure intervals, and composes the fusion feature vectors. The fused characteristic vector are input into the support vector machine for identify flow regime. The identification results for four typical flow regimes of air-water two-phase flow in horizontal pipe has shown that the ...
A procedure for code Verification by the Method of Manufactured Solutions (MMS) is presented. Although the procedure requires a certain amount of creativity and skill, we show that MMS can be applied to a variety of engineering codes which numerically solve partial differential equations. This is illustrated by detailed examples from computational fluid dynamics. The strength of the MMS procedure is that it can identify any coding mistake that affects the order-of-accuracy of the numerical method. A set of examples which use a blind-test protocol demonstrates the kinds of coding mistakes that can (and cannot) be exposed via the MMS code Verification procedure. The principle advantage of the MMS procedure over traditional methods of code Verification is that code capabilities are tested in full generality. The procedure thus results in a high degree of confidence that all coding mistakes which prevent the equations from being solved correctly ...
Twenty-six unclassified Campylobacter-like strains previously isolated from 15 chicken carcasses and caecal contents, together with two more strains isolated from chicken faeces on a different occasion, were identified as Helicobacter pullorum using various phenotypic identification methods. API Campy identification kits and a 16-test identification scheme developed for campylobacters failed to identify these bacteria, or identified them as Campylobacter spp. Eighteen strains (including the two isolated on a different occasion) were chosen for examination using a more comprehensive probabilistic identification scheme. Using this method, 14 of the 18 strains were identified as H. pullorum with ID scores > 95%; two strains were also identified as H. pullorum with lower ID scores. Of the remaining two strains, one was not identified with this scheme and the ...
The value of CT in respect of preoperative determination of tumour status and of tumour classification was studied using 127 histologically identified ovarial tumours as basis in a blind study via mutual image classification by the two participating institutes. The medium accuracy of diagnosis was 82%, but the results were found to be greatly dependent on tumour histology. Quotas of more than 90% were obtained in case of functional cysts, cystomas, cystadeno-carcinomas and dermoids, whereas classification was less successful with the other types of tumours such as germ cell tumours, tumours of the sexually differentiated stroma, metastases and tubo-ovarial abscesses.
Energy and angular double-differential cross-section (DDX) data of fragment production reactions by neutrons or protons are very scarce due to experimental difficulties of fragment detection. We adopted a Bragg curve spectrometer (BCS), which is a gridded-ionization chamber that can identify fragments on the basis of the Bragg peak value. We have been developing the BCS for neutron and proton-induced reactions applying the digital waveform analysis technique to obtain better ability of particle discrimination than the analog electronic circuit. (T. Tanaka)
Pippenger (2011) recently proposed a solution to the longstanding forward-bias puzzle. He argues that the puzzling estimates obtained using the standard equation for the efficient markets hypothesis are due to omitted variable bias. He identifies the missing variables as the future change in the forward exchange rate and the future interest differential. When these are added to the standard equation, he finds a one-to-one relationship between the future change in the spot rate and the forward premium. However, we argue that his equation can only test covered interest parity and offers no insight into the forward-bias puzzle.
Faults in shallow, unconsolidated sediments, particularly in coastal plain settings, are very difficult to discern during subsurface exploration yet have critical impact to groundwater flow, contaminant transport and geotechnical evaluations. This paper presents a case study using cross-over geophysical technologies in an area where shallow faulting is probable and known contamination exists. A comparison is made between Wenner and dipole-dipole resistivity data, ground penetrating radar, and high resolution seismic data. Data from these methods were verified with a cone penetrometer investigation for subsurface lithology and compared to existing monitoring well data. Interpretations from these techniques are compared with actual and theoretical shallow faulting found in the literature. The results of this study suggests that (1) the CPT study, combined with the monitoring well data may suggest that discontinuities in correlatable zones may indicate that faulting ...
A parallel event to the eleventh Conference of Parties (COP) to the United Nations Framework Convention of Climate Change was held to demonstrate examples of adaptation from around the world in the areas of food security, water resources, coastal zones, and communities/infrastructure. Panels on each theme presented examples from developing countries, countries in economic transition, and developed countries. These 4 themes were chosen because both mitigation and adaptation are essential to meeting the challenge of climate change. The objective of the event was to improve the knowledge of Canada's vulnerabilities to climate change, identify ways to minimize the negative effects of future impacts, and explore opportunities that take advantage of any positive impacts. This third session focused on how coastal communities are adapting to climate change in such places as Quebec, the Caribbean, and small Island States. It also presented the ...
Satellite imagery is a cost-effective tool for creating and updating basemaps of coastal zones, especially where existing maps and aerial photographs are unavailable, are out-of-date, or provide limited information. Reliable maps of coastal zones are particularly important for oil spill modelling programs. Color IR (multispectral) images with 20m x 20m ground resolution and black & white (panchromatic) images with 10m x 10m ground resolution of many coastlines around the globe have been acquired from 1986 to present by SPOT Image Corporation. We have digitally merged same-day SPOT panchromatic and multispectral imagery to provide maximum spatial resolution and permit excellent color differentiation of coastal zone features. This combination adequately discriminates individual features, including pipelines, offshore platforms, storage tanks, jetties, and shoreline type. The SPOT images were ...
The effect of insulin on protein biosynthesis was examined in differentiated 3T3-L1 and 3T3-F442A adipocytes. Insulin altered the relative rate of synthesis of specific proteins independent of its ability to hasten conversion of the fibroblast (preadipocyte) phenotype to the adipocyte phenotype. Although more than one pattern of response to insulin was observed, the authors focused on the induction of a Mr 33,000 protein which was identified as the glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH). Exposure of 3T3 adipocytes to insulin throughout differentiation specifically increased GAPDH activity and protein content by 2- to 3-fold as compared to 3T3 adipocytes differentiated in the absence of insulin. These changes in enzyme activity and content could be accounted for by a 4-fold increase in the relative rate of synthesis of GAPDH and a 9-fold increase in hybridizable mRNA levels. ...
High-resolution sequence stratigraphy has been applied widely in the petroleum exploration and development, many achievements have been achieved. However, it is in the beginning stage that high-resolution sequence stratigraphy is applied to explore the sandstone-type uranium deposits in Erlian Basin. By applying principles of high-resolution sequence stratigraphy and taking typical boreholes as an example, sedimentary cycles of Saihan Formation, the ore-bearing formation in Baiyinwula area are divided and correlated through cross sections. One long-term cycle (LSC_1), two middle-term cycles (MSC_1, MSC_2) have been identified in this study. Based on this and combined with the mineralization character of sandstone uranium deposits in this area, it is presented that the interlayer oxidation zone is developed mainly in the rising hemicycle of MSC_1 and uranium ore bodies predominantly in channel sand bodies that were developed in the system tract ...
Phosphoro-uraniferous deposit of Itataia is situated in Precambrian metamorphic terrains, into the litho-stratigraphic unit named Caico Complex. Regionally, the rocks are linearly folded, as a result of compressive tectonic that fits in the regmatic pattern. Rio Groairas' and Itatira's wrench faults form shearing couples in which the drag folds' climax are thrusting faults with axial plane dipping north. Uranium mineralization occurs into a phosphatic rock containing about 80% of collophane - 'collophanite - in association chiefly with marbles or feldsphatic rocks and gneisses. The ore (collophanite) occurs mainly as a stockwork, and it may be massive, (into big joints) or disseminated (impregnating the host rocks). Dark ore appears only in brecciated zones; it is richer in uranium content, but poorer in phosphorous. The highest grade ore is in a very fractured zone, associated to marbles. Supergene enrichment took place in this area. ...
Indian PHWRs are designed to operate with natural uranium (NU) as the main fuel. Earlier in the initial fresh core, to achieve flux flattening and hence to operate the reactor at design rated power, limited number of depleted uranium bundles were loaded in the central portion of the core. Presently even in fresh core about 40 % of the core is loaded with depleted uranium bundles (?0.6 wt % 235U) from the consideration of conserving the natural uranium fuel. This is achieved by loading most of the depleted bundles in the peripheral locations of the channels. Successful operation with large number of DU bundles in the fresh core has been proven in MAPS - 2 and MAPS - 1cores after EMCCR as well as in TAPP - 4. In these three reactors 100 % FP was possible even with 40 % DU bundles in the core. In TAPP-4 and 3 initial core, depleted bundles of 0.36 wt % 235U are also loaded to conserve the depleted bundles of 0.6 wt % 235U. Depleted uranium bundles (?0.6 wt % 235U) have been used in the ...
A significant challenge in proteomics biomarker research is to identify the changes that are of highest diagnostic interest, among the many unspecific aberrations associated with disease burden and inflammation. In the present study liver tissue specimens (n=18) from six experimental stages were collected from the resistant hepatocyte (RH) rat model of liver cancer and analyzed by 2D DIGE. The study included triplicates of regenerating liver, control "sham-operated" liver, three distinct premalignant stages and hepatomas. Out of 81 identified proteins two-thirds were differentially abundant in rat hepatomas compared to control rat liver and, secondly, the majority of proteins were also changed in precursor stages. This underscores the importance of adequate control samples in explorative cancer biomarker research. We confirm several proteomic changes previously identified in human hepatocellular ...
Simple, one-zone models for inhomogeneous chemical evolution of the Galactic halo are used to predict the number fraction of zero-metallicity, Population III stars, which currently is empirically estimated at < 4e-4. These analytic models minimize the number of free parameters, highlighting the most fundamental constraints on halo evolution. There are disagreements of at least an order of magnitude between observations and predictions in limiting cases for both homogeneous Simple Model and Simple Inhomogeneous Model (SIM). Hence, this demonstrates a quantitative, unambiguous discrepancy in the observed and expected fraction of Population III stars. We explore how the metallicity distribution of the parent enrichment events f(z_0) drives the SIM and predictions for the Population III fraction. The SIM shows that the previously-identified "high halo" and "low halo" populations are consistent with a continuous evolutionary progression, and ...
A thermodynamic analysis of the behaviour of Alloy 800 in helium based atmospheres relevant to the High Temperature Gas Cooled Reactor indicates that, depending upon the precise gas composition, oxidation and carburisation, or carburisation alone may be expected. The prime influence appears to be the moisture level. The morphology and structure of the reaction products are discussed. It is shown that the 'reactive' elements chromium, manganese, titanium and silicon are concentrated in the oxide scale which is normally duplex in structure. Aluminium oxide is formed at grain boundaries and in an internal oxidation zone together with titanium and sometimes silicon. In carburising conditions, mixed titanium-chromium carbides are formed. When this occurs, intergranular penetration is maximised. Weight gain data are assessed and briefly described and a tentative model for the mechanism of corrosion of Alloy 800 in HTR helium is proposed. Areas for further work are ...
Nineteen fungal strains having an ability to oxidize elemental sulfur in mineral salts medium were isolated from deteriorated sandstones of Angkor monuments. These fungi formed clearing zone on agar medium supplemented with powder sulfur due to the dissolution of sulfur. Representative of the isolates, strain THIF01, was identified as Fusarium solani on the basis of morphological characteristics and phylogenetic analyses. PCR amplification targeting 16S rRNA gene and analyses of full 16S rRNA gene sequence indicated strain THIF01 harbors an endobacterium Bradyrhizobium sp.; however, involvement of the bacterium in the sulfur oxidation is still unclear. Strain THIF01 oxidized elemental sulfur to thiosulfate and then sulfate. Germination of the spores of strain THIF01 was observed in a liqui...
A study, based on a literature review was made to examine currently recommended meteorological measurement programs and diffusion prediction methods for nuclear power plants to determine their adequacy for plants located in coastal zones. Although procedures for handling the near-worst case (stable, light-wind situation) were judged adequately conservative, deficiencies in guidelines and procedures were found with respect to the following: failure to consider the role of coastal internal boundary layers; specifications for tower locations and instrument heights; methods of classifying atmospheric stability; methods of allowing credit for plume meander, and models specified for diffusion calculations. Recommendations were made for changes in the guidelines applicable to these topics. Areas in which additional research is needed were identified.
The carbonate rocks of the Lower Ordovician Majiagou Formation represent important hydrocarbon reservoirs in the Ordos basin in the western part of the North China plate. Cores and thin sections from more than 60 wells were examined. The main reservoir in the Majiagou Formation consists of fine crystalline dolomite, which was altered by meteoric water during an extended subaerial exposure. Three phreatic zones have been identified in the Majiagou Formation in the northern part of the basin. Oxygen isotopes and fluid inclusion microthermometry data indicates that the porosity developed during the early karst event was considerably reduced by the late-stage, coarse crystalline calcite cements that appear to be related to hydrothermal fluids during deep burial. It was concluded that the main factors that determine the porosity and permeability of these carbonate reservoirs are dolomitization, karstification, and calcite cementation.
Understanding the processes responsible for coastal change is important for managing our coastal resources, both natural and economic. The current scientific understanding of coastal sediment transport and geology suggests that examining coastal processes at regional scales can lead to significant insight into how the coastal zone evolves. To better identify the significant processes affecting our coastlines and how those processes create coastal change we developed a Coupled Ocean-Atmosphere-Wave-Sediment Transport (COAWST) Modeling System, which is comprised of the Model Coupling Toolkit to exchange data fields between the ocean model ROMS, the atmosphere model WRF, the wave model SWAN, and the sediment capabilities of the Community Sediment Transport Model. This formulation builds upon ...
The stability of a forced-flow cooled superconducting coil is investigated by use of the numerical simulation. The numerical code to integrate the simultaneous partial differential system composed of the 1 D hydrodynamic equations and the 1 D thermal conduction equation has been developed and stability margins are evaluated as functions of coolant mass flow rate, operation current and imposed magnetic field. The results of computations show that the stability margin is multi-valued with respect to these operation parameters, as expected from the experimental results. It is also shown that the appearance of the first unstable regime is closely related to the existance of the stagnant region located at the upstream side of the heated zone and that the second stable regime appears because the heat transfer is appreciably enhanced by the induced backflow due to the thermal expansion of coolant. 13 refs., 13 figs., 1 tab.
This paper presents a methodology for modeling slug initiation and growth in horizontal ducts. Transient two-fluid equations are solved numerically using a class of high-resolution shock capturing methods. The advantage of this method is that slug formation and growth in a stratified regime can be calculated directly from the solutions to the flow field differential equations. In addition, by using high-resolution shock capturing methods that do not contain numerical diffusion, the discontinuity generated by slugging in the flow field can be modeled with good accuracy. The two-fluid model is shown to be well-posed mathematically only under certain conditions. Under these circumstances, the two-fluid model is capable of correctly predicting and modeling the flow physics. When ill-posed, an unbounded instability occurs in the flow field solution, and the instability amplitude increases exponentially with decreasing mesh sizes. This work shows that there are three ...
A numerical model was developed to simulate the combined effects of heat transfer, magnetite oxidation, and NO{sub x} formation in a grate-kiln furnace for taconite pellet induration. Heat transfer from the flame in the kiln was described by the net radiation method. The shrinking core model was used to account for magnetite oxidation on the grate. A novel approach to oxidation of tumbling pellets in a kiln was derived. The Zeldovich mechanism was used to predict thermal NO generation. Temperature fluctuations in the gas streams were estimated with a clipped Gaussian probability density function. The thermal energy balances and mass balances resulted in coupled systems of first-order differential equations, which were solved numerically. The model is capable of predicting NO production and magnetite oxidation in agreement with observation of plant performance. Although the design of the grate-kiln system is for efficient heat and mass transfer, it may not be the ...
Distance protection, differential protection and directional comparison schemes are presently used for protecting transmission lines. Directional comparison relays are set to respond to faults in the protection zone without intentional time delay and are, therefore, used where high-speed fault clearing is needed. Artificial Neural Networks (ANNs) can handle most situations which cannot be defined sufficiently for finding a deterministic solution. The design and testing of an ANN for directional comparison protection of transmission lines are presented in this paper. Training patterns were generated using voltage and current samples for faults at various locations along a transmission line. The faults were simulated using an electromagnetic transient program and a sample three-phase power system. The performance of the proposed discriminator was checked using data simulated for testing and the fault data recorded from 240 kV and 500 kV lines. ...
Seismic transects in this area show a strongly reflective Moho of generally low relief, which, in the area of modern transects, consists of a thin zone (< 2 km thick) of short reflectors. The upper mantle is transparent and has a P{sub n} of 7.8-8.0 km/s similar to much of the western US. A lower crustal zone, 2-13 km thick, has variable internal reflectivity and a relatively low velocity of 6.6-6.8 km/s. Upper mantle peridotite xenoliths show both ductile and brittle deformational features and have structures and composition affected by magmatic intrusion; intrusions form complex dike systems and extensive zones of grain boundary infiltration in peridotite xenoliths. Whereas melt infiltration preceded and followed ductile deformation, brittle deformation, represented by closely spaced joint systems and faults, followed ductile deformation and is related to the youngest magmatic episodes. Lower crustal xenoliths are ...
BackgroundMetastases to the stomach from an extra-gastric neoplasm are an unusual event, identified in less than 2% of cancer patients at autopsy. The stomach may be involved by hematogenous spread from a distant primary (most commonly breast, melanoma or lung), or by contiguous spread from an adjacent malignancy, such as the pancreas, esophagus and gallbladder. These latter sites may also involve the stomach via lymphatic or haematogenous spread. We present three cases of secondary gastric malignancy.Methods/ResultsThe first is a 19-year-old male who received a diagnosis of testicular choriocarcinoma in September 2004. Metastatic malignancy was demonstrated in the stomach after partial gastrectomy was performed to control gastric hemorrhage.The second is a 75-year-old male, generally well, who was diagnosed with adenocarcinoma of the lung in September 2005. Poorly differentiated adenocarcinoma of the lung was demonstrated in a subsequent ...
The levels of General Transcription Factor (TF) IIA were examined during mammalian brain development and in rat embryo fibroblasts and transformed cell lines. The large TFIIA subunit paralogues ab and t are largely produced in unsynchronized cell lines, yet only TFIIA ab is observed in a number of differentiated tissue extracts. Steady-state protein levels of the TFIIA t, ab, and g subunits were significantly reduced when human embryonal (ec) and hepatic carcinoma cell lines were stimulated to differentiate with either all-trans-retinoic acid (ATRA) or sodium butyrate. ATRA-treated NT2-ec cells required replating to induce a neuronal phenotype and loss of detectable TFIIA t and g proteins. High levels of TFIIA t, ab, and g and Sp factors were identified in extracts from human fetal and rat...
Aiming at the non-stationary characteristics of differential pressure fluctuation signals of gas-liquid two-phase flow, and the slow convergence of learning and liability of dropping into local minima for BP neural networks, flow regime identification method based on Singular Value Decomposition (SVD) and Least Square Support Vector Machine (LS-SVM) is presented. First of all, the Empirical Mode Decomposition (EMD) method is used to decompose the differential pressure fluctuation signals of gas-liquid two-phase flow into a number of stationary Intrinsic Mode Functions (IMFs) components from which the initial feature vector matrix is formed. By applying the singular vale decomposition technique to the initial feature vector matrixes, the singular values are obtained. Finally, the singular values serve as the flow regime characteristic vector to be LS-SVM classifier and flow regimes are identified by the output of the ...
The Siberian Altai covers about 70% of the area of all south Siberian glaciers, which provide fresh water to the upper tributaries of the Ob and Yenisey rivers. The observed air temperature has increased by 1.2 deg. C over northern Eurasia during the last 120 years, affecting the degradation of the Siberian Altai glaciers. In this study, we estimated glacier area changes in the Aktru River basin (44.8 km{sup 2}), located in the central Altai mountains. We used the 1952, 1966, 1975 and 2006 remote sensed images with 0.6-3.0 m spatial resolution (aerial photographs, Corona and PRISM satellite images) and differential GPS (DGPS) data. From 1952 to 2006, the total glacier area in the Aktru basin shrank by 7.2% (1.2 km{sup 2}). During the last three decades, the rate of glacier area loss increased by a factor of 1.8, thus resembling trends in other mountain systems of Eurasia (Alps, Tien Shan). The glacier area changes were caused mainly by increase of summer air ...
The Siberian Altai covers about 70% of the area of all south Siberian glaciers, which provide fresh water to the upper tributaries of the Ob and Yenisey rivers. The observed air temperature has increased by 1.2 deg. C over northern Eurasia during the last 120 years, affecting the degradation of the Siberian Altai glaciers. In this study, we estimated glacier area changes in the Aktru River basin (44.8 km"2), located in the central Altai mountains. We used the 1952, 1966, 1975 and 2006 remote sensed images with 0.6-3.0 m spatial resolution (aerial photographs, Corona and PRISM satellite images) and differential GPS (DGPS) data. From 1952 to 2006, the total glacier area in the Aktru basin shrank by 7.2% (1.2 km"2). During the last three decades, the rate of glacier area loss increased by a factor of 1.8, thus resembling trends in other mountain systems of Eurasia (Alps, Tien Shan). The glacier area changes were caused mainly by increase of summer air temperature by ...
The passive continental margin in the northern South China Sea is a weakly active area. It has been found to be favorable for large gas field development and also to be profitable for gas hydrate. The active faults, diapir structure, slump deposits, faults break of slopes, gas chimneys and sandstone of submarine fan, control the concentration of gas hydrate. Gas chimneys are widely distributed in the northern South China Sea. They supply the pathway for migration of deeper gas to gas hydrate stability zones especially in the basin of tectonic inactive zone. This paper discussed the geological structures of gas hydrate occurrence in gas fields and presented a detailed analysis of gas chimneys within the northern slope of the South China Sea. The paper described the geological setting of the Qiongdongnan Basin and provided information on the data description and processing. Two multichannel seismic (MCS) reflection profiles were used for the ...
The purpose of this study was to compare a double freeze-thaw protocol to a triple freeze-thaw protocol for pulmonary cryoablation utilizing an in vivo porcine lung model. A total of 18 cryoablations were performed in normal porcine lung utilizing percutaneous technique with 9 each in a double- (10-5-10) and triple-freeze (3-3-7-7-5) protocol. Serial noncontrast CT images were obtained during the ablation. CT imaging findings and pathology were reviewed. No imaging changes were identified during the initial freeze cycle with either protocol. However, during the first thaw cycle, a region of ground glass opacity developed around the probe with both protocols. Because the initial freeze was shorter with the triple freeze-thaw protocol, the imaging findings were apparent sooner with this protocol (6 vs. 13 min). Also, despite a shorter total freeze time (15 vs. 20 min), the ablation zoneidentified with the triple freeze-thaw ...
Thyroid cancer is the most frequently diagnosed endocrine cancer and causes more deaths than all other endocrine cancers combined. Research findings support the concept that a subpopulation of thyroid cancer cells displays properties characteristic of stem cells. These putative cancer-forming entities drive tumorigenesis as a result of their dual ability to undergo self-renewal and to differentiate into various types of cancer cells; they also mediate metastasis and are resistant to the effects of chemotherapy and radiation therapy. This Review discusses the cellular origin of thyroid cancer and the properties of the thyroid cancer stem cell niche. The article critically evaluates the methods used to identify molecular markers expressed by thyroid-cancer-initiating cells and outlines prosp...
Nano- and microstructured surfaces are known to impact on the binding and differentiation of cells, but the detailed basic understanding of the underlying regulatory mechanisms is still scarce, which impedes the rational design of smart biomaterials. Towards a comprehensive analysis of the interplay between topographical parameters such as feature design and lateral and vertical dimensions we here report on a combinatorial screening approach, BioSurface Structure Array (BSSA) of test squares each with a distinct topography. Using such BSSA libraries of 504 topographically distinct surface structures, we have identified combinations of size, gap and height of structures which enhance mineralization as well as the expression of osteogenic markers of a preosteoblastic murine cell line. This g...
We previously reported that puromycin-insensitive leucyl-specific aminopeptidase (PILSAP) is required for vascular endothelial growth factor (VEGF)- and basic fibroblast growth factor (bFGF)-induced angiogenesis and for endothelial differentiation from embryonic stem (ES) cells via the aminopeptidase activity of PILSAP. In this study, we searched for molecules that function during angiogenesis with PILSAP. We performed proteome analysis of nuclear extracts from embryoid bodies (EBs) made from ES cells transfected with mutant PILSAP lacking aminopeptidase activity and mock EBs. We identified pigpen, a 67-kDa nuclear coiled body component protein. Immunoprecipitation and western blotting demonstrated the binding of PILSAP and pigpen in endothelial cells (ECs), and this interaction was enhanc...
The identification of the unknown parameters of the Duffing's mechanical system, based on an algebraic approach, is presented. This approach is fast, accurate, and simple to numerically implement. Also, the method, combined with a suitable invariant filter, can became robust against high frequency output measurement noises. Our method uses the availability of one measurable output and produces an exact formula for the unknown parameters, which may be realized in terms of iterated convolutions. First, we show that the Duffing's system parameters are linearly identifiable with respect to the position variable, then we obtain a linear system where the unknowns are the unavailable parameters. Suitable algebraic operations on the output differential equations makes the identification schema independent of the unavailable initial conditions of the underlying nonlinear dynamical system.
As a new high-voltage cathode candidate for post 4V cathodes, ordered-olivine LiCoPO{sub 4} and fluoride phosphate, Li{sub 2}CoPO{sub 4}F were synthesized by solid-state reaction. Their structures were identified by neutron diffraction. The 5V discharge profiles were demonstrated using coin-type cells. Two important issues for commercial use, metal dissolution and oxygen release at elevated temperatures, were also tested with an atomic absorption spectrophotometer and differential scanning calorimeter, respectively. (author)
Hepatocellular carcinoma (HCC) represents a major health problem as it afflicts an increasing number of patients worldwide. Albeit most of the risk factors for HCC are known, this is a deadly syndrome with a life expectancy at the time of diagnosis of less than 1?year. Definition of the molecular principles governing the neoplastic transformation of the liver is an urgent need to facilitate the clinical management of patients, based on innovative methods to detect the disease in its early stages and on more efficient therapies. In the present study, we have combined the analysis of a murine model and human samples of HCC to identify genes differentially expressed early in the process of hepatocarcinogenesis, using a microarray-based approach. Expression of 190 genes was impaired in murine ...
A web-based decision support tool, zone mapping application for precision farming (ZoneMAP, External Reference Not Shown ), has been developed to automatically determine the optimal number of management zones and delineate them using satellite imagery and field data provided by users. Application rates, such as of fertilizer, can be prescribed for each zone and downloaded in a variety of formats to ensure compatibility with GPS-enabled farming equipment. ZoneMAP is linked to Digital Northern Great Plains, a web-based application which hosts an archive of satellite imagery, as well as high resolution imagery from airborne sensors. Management zones created by ZoneMAP mapped natural variation of the soil organic matter and other nutrients relatively well and were consistent with zone maps cre...
Gastric stromal tumors are an ill-defined group of lesions arising from muscle wall cells and characterized by extremely variable biological patterns. Thanks to modern immunohistochemical and ultrastructural techniques, four main classes of these lesions have been identified, namely: (1) tumors with differentiation toward smooth muscle cells; (2) tumors with differentiation toward neural elements; (3) tumors with differentiation toward neural elements; (3) tumors with dual differentiation toward either cell type. It was investigated the yield of CT in diagnosing and characterizing gastric stromal tumors. It was retrospectively reviewed the CT findings of 38 patients (15 men and 23 women; mean age 51 years) with pathologically proven gastric stromal tumors, namely 31 of myoid origin, 4 of neural origin, 2 with both muscle and neural differentiation, 1 lacking ...
Ageing of nuclear power plants means evolution of material or equipment properties on one side, and evolution of personnel skill and procedure adequacy on the other side, both of which, after a certain time, may not be compatible with the required safety provisions, or with an economic operation of the plant. Repair or replacement of components, as well as change in service conditions for a better compatibility with component reduced capabilities can be used to mitigate ageing effects. The paper summarises the results of a study conducted in this field with the support of the European Commission. It presents: the synthesis of the work done under international auspices, and in the European context; the comparison of ageing management approaches used in several European countries with international recommendations; the summary of the various potential phenomena and their governing parameters, the methods of in-service ageing identification and possible mitigation methods; illustrative ...
Abstract in english The tegument surface of the adult schistosome, bounded by a normal plasma membrane overlain by a secreted membranocalyx, holds the key to understanding how schistosomes evade host immune responses. Recent advances in mass spectrometry (MS), and the sequencing of the Schistosoma mansoni transcriptome/genome, have facilitated schistosome proteomics. We detached the tegument from the worm body and enriched its surface membranes by differential extraction, before subjecting t (more) he preparation to liquid chromatography-based proteomics to identify its constituents. The most exposed proteins on live worms were labelled with impearmeant biotinylation reagents, and we also developed methods to isolate the membranocalyx for analysis. We identified transporters for sugars, amino acids, inorganic ions and water, which confirm the importance of the tegument plasma membrane in nutrient acquisition and solute ...
Using a syngeneic p53-null mouse mammary gland tumor model that closely mimics human breast cancer, we have identified, by limiting dilution transplantation and in vitro mammosphere assay, a Lin(-)CD29(H)CD24(H) subpopulation of tumor-initiating cells. Upon subsequent transplantation, this subpopulation generated heterogeneous tumors that displayed properties similar to the primary tumor. Analysis of biomarkers suggests the Lin(-)CD29(H)CD24(H) subpopulation may have arisen from a bipotent mammary progenitor. Differentially expressed genes in the Lin(-)CD29(H)CD24(H) mouse mammary gland tumor-initiating cell population include those involved in DNA damage response and repair, as well as genes involved in epigenetic regulation previously shown to be critical for stem cell self-renewal. These studies provide in vitro and in vivo data that support the cancer stem cell (CSC) hypothesis. Furthermore, this p53-null mouse mammary tumor model may allow ...
The report provides and overview of calculation models for the simulation of airflows and deals comprehensively with field and multi-zone models as well as the coupling of individual zone and multi-zone models. Examples of calculations are given. figs., tabs., refs.
The primary goal of this project is to increase the availability and ease of access to critical data on the Mesaverde and Dakota tight gas reservoirs of the San Juan Basin. Secondary goals include tuning well log interpretations through integration of core, water chemistry and production analysis data to help identify bypassed pay zones; increased knowledge of permeability ratios and how they affect well drainage and thus infill drilling plans; improved time-depth correlations through regional mapping of sonic logs; and improved understanding of the variability of formation waters within the basin through spatial analysis of water chemistry data. The project will collect, integrate, and analyze a variety of petrophysical and well data concerning the Mesaverde and Dakota reservoirs of the San Juan Basin, with particular emphasis on data available in the areas defined as tight gas areas for purpose of FERC. A relational, geo-referenced database ...
Liquid Zone Control (LZC) System is a 'first-of-its-kind' reactivity control device, designed and implemented at TAPP-3 and 4. The system provides zonal and bulk power control. The system consists of fourteen Zone Control Compartments (ZCCs) containing demineralised light water as neutron absorber. Reactivity control is achieved by varying the level of water in the compartments bi-directionally. Six in-core zircaloy assemblies, housing the fourteen ZCCs and an elaborate process system constitute the LZC system. Measurement of water levels in the ZCCs is done using helium bubbler method. Reliability of ZCC water level measurement is of paramount importance. Commissioning and operating the new system trouble free was a challenge, considering the complex nature of the system. While commissioning the system, level measurement of one of the ZCCs (ZCC - 1) was found erratic and inconsistent. Methodologies were developed to ...
The studies of {sup 137}Cs and {sup 239+240}Pu distributions in surface seawater at South China Sea within the Exclusive Economic Zone (EEZ) of Peninsular Malaysia were carried out in June 2008. The analysis results will serve as additional information to the expanded baseline data for Malaysia's marine environment. Thirty locations from extended study area were identified in the EEZ from which large volumes of surface seawater samples were collected. Different co-precipitation techniques were employed to concentrate cesium and plutonium separately. A known amount of {sup 134}Cs and {sup 242}Pu tracers were used as yield determinant. The precipitate slurry was collected and oven dried at 60 {sup o}C for 1-2 days. Cesium precipitate was fine-ground and counted using gamma-ray spectrometry system at 661.62 keV, while plutonium was separated from other radionuclides using anion exchange, electrodeposited and counted using alpha ...
An initial review was conducted of the current treatment operations for remediation of groundwater contaminated with trichloroethene (TCE) at the Fort lewis Logistics Center. Results from this review indicate the two pump-and-treat systems are effectively containing the TCE plume within the upper unconfined aquifer (Vashon Drift). However, mass balance calculations show the existing treatment systems alone will not accomplish the remedial action objective of cleaning up the aquifer to drinking water standards within 30 years as specified in the Record of Decision (ROD). This conclusion is based on the estimated mass of TCE at the source term (51,000 kg), the calculated mass of TCE in the aquifer (4,900 kg), and the removal rate of the pump-and-treat systems that currently ranges from 324 to 667 kg of TCe per year. Four areas within the TCE plume have been identified where enhancements could be made to the existing treatment operations. These are, Area 1 -- the ...
The electronic band structure, transport properties, and lattice dynamics in AuX_2 (X = Al, Ga and In) under high pressure have been extensively studied with full potential linearized augmented plane wave and pseudopotential plane wave methods. The theoretical results for the electronic band structure and Fermi surface reveal pressure-induced electronic topological transitions (ETTs) in AuGa_2 and AuIn_2, while they are absent in AuAl_2, in excellent agreement with the experimental observations. Moreover, calculations of the transport properties at different pressures reveal subtle changes in the band structure close to the Fermi surface of the three intermetallic compounds. It is clear that the anomalies in transport properties are due to ETTs. Interestingly, a pressure-induced soft transverse acoustic (TA) phonon mode is identified only in AuGa_2. The TA phonon instability at the Brillouin zone boundary L point might be responsible for the ...
Union Oil Company drilled four geothermal test wells in the Cove Fort-Sulphurdale KGRA between 1975 and 1979. A fairly complete suite of well logs were recorded for the three deeper holes, and these data are presented as composite well log plots in this report. The composite well log plots have facilitated the interpretation of limestone, dolomite, sandstone, quartz-monzonite, serpentine, and volcanic lithologies and the identification of numerous fractures. This has been especially helpful because of the extensive lost circulaton zones and poor cuttings recovery. Intraformational flow was identified by a fluid migration-temperature tracer log at depth in CFSU 31-33. Well log crossplots were computed to assist in lithologic identification and the determination of physical properties for specific depth intervals in a given hole. The presence of hydrous minerals sometimes results in neutron porosity somewhat higher than the true nonfracture ...
Excessive erosion of the labyrinth seal of a 100 MW geothermal turbine has been investigated. This study used computational fluid dynamics (CFD) and aims to identify one cause of erosion and a possible solution for substantially reducing it. The predictions were based upon a numerical calculation using a CFD model of the labyrinth seal with a water/steam flow containing hard solid particles and solved with a commercial CFD code: Fluent V5.0. The results confirmed the existence of flow conditions that play a major role in the rotor labyrinth seal erosion. Afterwards, the flow path was simulated with changes of rotor labyrinth seal geometry, which are indeed feasible of being implemented. The results confirmed that it is possible to reduce the erosion process by approximately 80% by incorporating a steam flow deflector in the fourth stage diaphragm, which changes the steam flow direction in the inlet zone to the rotor labyrinth seal channel, ...
In this study, dissimilar welds between HP heat-resistant steel and Incoloy 800 were made with four different filler materials including: 309 stainless steel and nickel-based Inconel 82, 182 and 617. The microstructure of the base metals, weld metals and their interfaces were characterized by utilizing optical and scanning electron microscopy. Grain boundaries migration in the weld metals was studied. It was found that the migration of grain boundaries in the Inconel 82 weld metal was very extensive. Precipitates of TiC and M_2_3C_6 (M = Cr and Mo) in the Inconel 617 weld metal are identified. The necessary conditions for the formation of cracks close to the fusion line of the 309-HP joints are described. Furthermore unmixed zone near the fusion line between HP steel base metal and Inconel 82 weld metal is discussed. An epitaxial growth is characterized at the fusion line of the 309-Alloy 800 and Inconel 617-Alloy 800 joints.
Ternary R_2TSi_3 intermetallic compounds (R=Rare Earth, T=Transition Metal) with hexagonal AlB_2-type crystallographic structure are known because of their interesting physical properties. Pr_2PdSi_3 single crystals were grown by a vertical floating zone method. The compound exhibits congruent melting behavior at a liquidus temperature of about 1770 C. Single crystalline samples show a huge anisotropy at low temperatures due to the crystal electric field effect and order antiferromagnetically below the Neel temperature T_N=2.17 K. This value approximately obeys the linear de Gennes scaling for this class of compounds. The [001] orientation was identified as the magnetic easy axis at room temperature. At lower temperature (#approx#20 K) magnetic easy and hard axes interchange with each other. Two additional magnetic phase transitions were observed at temperatures below 1 K.
In the present study, the type and densities of defects in AlN crystals grown on 6H-SiC seeds by the sublimation-recombination method were assessed. The positions of the defects in AlN were first identified by defect selective etching (DSE) in molten NaOH-KOH at 400 C for 2 minutes. Etching produced pits of three different sizes: 1.77 m, 2.35 m , and 2.86 m. The etch pits were either aligned together forming a sub-grain boundary or randomly distributed. The smaller etch pits were either isolated or associated with larger etch pits. After preparing crosssections of the pits by the focused ion beam (FIB) technique, transmission electron microscopy (TEM) was performed to determine which dislocation type (edge, mixed or screw) produced a specific etch pit sizes. Preliminary TEM bright field and dark field study using different zone axes and diffraction vectors indicates an edge dislocation with a Burgers vector 1/3[1120] is associated with the ...
The primary purpose of the pilot Coal Compilation Project is to provide coal resource maps to stimulate and support industry exploration programs and to assist government in matters of resource management. An essential feature of the program is the use of cost effective Geoscience Information System (GSIS) technology that allows the database and various thematic maps to be analysed, updated and displayed with complete flexibility at any scale. This report describes the main features (geology, resource management, exploration history, coal occurrences etc.) of the study area, mapsheet NTS 83E/9 (Moberly Creek), and includes a copy of the 1:50,000 scale map produced. The study area is located in West-central Alberta and contains coal measures deposited amid thick successions of sandstones, siltstones, shales and conglomerates. These coal-bearing sequences are part of the Luscar Group, Upper Cretaceous Brazeau Formation and Paleocene Coalspur Formations. Coal seams have been ...
The Hanford Site, Richland, Washington, contains over 1,500 identified waste sites and numerous groundwater plumes that will be characterized and remediated over the next 30 years. As a result of the Hanford Federal Facility Agreement and Consent Order, the US Department of Energy (DOE) has initiated a remedial investigation/feasibility study (RI/FS) at the 200-BP-1 operable unit. The 200-BP-1 RI/FS is the first Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) investigation on the Hanford Site that involves highly radioactive and chemically contaminated soils. The initial phase of site characterization was designed to assess the nature and extent of contamination associated with the source waste sites within the 200-BP-1 operable unit. Characterization activities consisted of drilling and sampling, chemical and physical analysis of samples, and development of a conceptual vadose zone model. These data were then ...
The purpose of this study is to identify the radiative heat transfer augmentation by a coaxial cylinder introduced in the infinite cylindrical pipe enclosing a participating gas. The gas is either a mixture of water vapor and carbon dioxide or gray. The gas is assumed to be homogeneous at a constant temperature, and has a refractive index of unity. All of the surfaces are opaque and gray, diffusely emitting and reflecting at a constant temperature. The effect of system diameter, diameter ratio, wall emittances, gas and surface temperatures, mixture component on heat transfer augmentation are studied by using the zone method with participating gas radiative properties evaluated from the weighted sum of gray gases model. From the radiative equilibrium condition, the installed wall temperature is formulated and calculated by the iteration method. If the medium is a gray gas, the augmentation observed are negligible. For the range of values studied ...
The implementation of satellite remote sensing data for monitoring anthropogenic pollution in the USSR is described. Space-based monitoring systems offer the opportunity to identify pollution sources, track the spread of pollutants on the surface and in the air, and characterize land use patterns that cause erosion. Furthermore, vegetation under attack by polluting agents can be recognized by color changes, and water pollution in lakes, coastal zones, and in rivers near industrial areas and ports can be measured for the total affected area. The data have thus far been taken with instrumentation on board the Salyut space station, the Meteor-Priroda satellite, and from the Landsat MSS scanner. It is noted that the transboarder transport of pollutants necessitates sharing data with agencies of other nations, and that a data base must be developed to define procedures and instrumentation for given pollutants, algorithms for processing the data, and ...
Greenhouse-effect induced climate change repercussions will, via the catchment areas of big rivers, eventually arrive in amplified form at the far downstream coastal zones of the world. In the coastal zone these imported problems will add to the locally exerted climate change effects, while the climate change induced sea-level rise will attack the coastal zone from the other side, both by flooding and by saline groundwater intrusion. These multiple problems will hit the coastal zone, which is already under increasing stress. The combined threats require fast and massive support for national Coastal Zone Management capabilities, which could help to limit the damage and to support planning for sustainable development. Recommendations are presented to facilitate implementation of Coastal Zone Management units in all coastal countries by the year 2000.
Rice is a very important food staple that feeds more than half the world's population. Two major Asian cultivated rice (Oryza sativa L.) subspecies, japonica and indica, show significant phenotypic variation in their stress responses. However, the molecular mechanisms underlying this phenotypic variation are still largely unknown. A common link among different stresses is that they produce an oxidative burst and result in an increase of reactive oxygen species (ROS). In this study, methyl viologen (MV) as a ROS agent was applied to investigate the rice oxidative stress response. We observed that 93-11 (indica) seedlings exhibited leaf senescence with severe lesions under MV treatment compared to Nipponbare (japonica). Whole-genome microarray experiments were conducted, and 1,062 probe sets were identified with gene expression level polymorphisms between the two rice cultivars in addition to differential expression under MV treatment, which were ...
This report describes modelling where the hydrological modelling system MIKE SHE has been used to describe surface hydrology, near-surface hydrogeology, advective transport mechanisms, and the contact between groundwater and surface water within the SKB site investigation area at Laxemar. In the MIKE SHE system, surface water flow is described with the one-dimensional modelling tool MIKE 11, which is fully and dynamically integrated with the groundwater flow module in MIKE SHE. In early 2008, a supplementary data set will be available and a process of updating, rebuilding and calibrating the MIKE SHE model based on this data set will start. Before the calibration on the new data begins, it is important to gather as much knowledge as possible on calibration methods, and to identify critical calibration parameters and areas within the model that require special attention. In this project, the MIKE SHE model has been further developed. The model area has been ...
The connection between W-algebras and the algebra of differential operators is conjectured. The bosonized representation of the differential operator algebra with c=-2n and all the subalgebras are examined. The degenerate representations and null-state classifications for c=-2 are presented. (orig.).
Spinal Ewing's sarcomas are rare and cause problems in differential diagnosis. The radiologic, nuclear medicine and CT findings in two children with histologically proven Ewing's sarcoma are presented and problems in differential diagnosis discussed. Biopsy should be done early. (orig.).
Ordos basin lies in the north-central China, in a compression tectonic regime, with an area of approximately 250,000 km{sup 2}, including several pay zones ranging from Cambrian to Jurassic. It is one of the earliest-formed marine to continental-superimposed basin in China, characterized by Proterozoic basin-marginal rifling and Lower-Paleozoic carbonate platform development followed by western thrusting and foreland depression during Mesozoic. It underwent several tectonic movements and is covered by several structural layers, with many play types developed, primarily thrust and anticlinal plays in the west, and differential compaction (river-channel sand lens) or drape as well as buried hill plays in the basin center and east. Ordos basin is a prolific gas basin with an estimated resource potential of gas 656,091 billion m{sup 3} in the Paleozoic strata and oil 2.0474 billion tons in the Mesozoic strata. In 1986, in the western part of the ...
We present local two-dimensional and three-dimensional hybrid numerical simulations of particles and gas in the midplane of protoplanetary disks (PPDs) using the Athena code. The particles are coupled to gas aerodynamically, with particle-to-gas feedback included. Magnetorotational turbulence is ignored as an approximation for the dead zone of PPDs, and we ignore particle self-gravity to study the precursor of planetesimal formation. Our simulations include a wide size distribution of particles, ranging from strongly coupled particles with dimensionless stopping time #tau#_s #ident to# #OMEGA#t_s_t_o_p = 10"-"4 (where #OMEGA# is the orbital frequency, t_s_t_o_p is the particle friction time) to marginally coupled ones with #tau#_s = 1, and a wide range of solid abundances. Our main results are as follows. (1) Particles with #tau#_s #approx#> 10"-"2 actively participate in the streaming instability (SI), generate turbulence, and maintain the height of the ...
The choice of treatment in adult skeletal Class III occlusions often poses a particularly tricky problem for the orthodontist. Faced with the option of either orthodontic camouflage or orthognathic surgery, the clinician's clinical experience is of paramount importance, especially in borderline cases. The aim of our study was to uncover a guide model enabling the practitioner to distinguish between skeletal Class III cases which can be suitably treated with orthodontics and those requiring orthognathic surgery. The lateral headfilms of 47 adult patients exhibiting skeletal Class III occlusions were analyzed. The orthodontic group comprised 22 patients and the surgical group 25. Twenty-seven linear, proportional and angular measurements were scrutinized. Stepwise discriminant analysis was used to identify the dentoskeletal and esthetic variables which most distinguished the two groups. The Holdaway angle was chosen to differentiate between ...
The State of the Espirito Santo will become until the end of 2008, one of the main producers and natural gas exporters of Brazil, where, according to PETROBRAS, the State will produce about 20 million /day m{sup 3}, what it will go to contribute significantly for reduction of the dependence of the Bolivian gas, and still to give support to the natural gas sector in Brazil. The Intention of this work, is to identify proposals so that it has left of the gas produced in the State of the Espirito Santo, has a differentiated price. It does not make sensible the State to pay for the gas that is removed in its proper territory the same price that paid Sao Paulo for the gas that consumes imported of national Bolivia. With the markdown of the gas the State will be able to attract investments of great transport, to generate job and income and to advance in the question of the regional development that is of great importance for the developed cities less. ...
Mutations in the mouse formin (Fmn) gene, formerly known as the limb deformity (ld) gene, give rise to recessively inherited limb deformities and renal malformations or aplasia. The Fmn gene encodes many differentially processed transcripts that are expressed in both adult and embryonic tissues. To study the genomic organization of the Fmn locus, we have used Fmn probes to isolate and characterize genomic clones spanning 500 kb. Our analysis of these clones shows that the Fmn gene is composed of at least 24 exons and spans 400 kb. We have identified two novel exons that are expressed in the developing embryonic limb bud as well as adult tissues such as brain and kidney. We have also used a microsatellite polymorphism from within the Fmn gene to map it genetically to a 2.2-cM interval between D2Mit58 and D2Mit103. 36 refs., 6 figs., 1 tab.
Throughout their history, Americans have believed that citizens' fulfillment of their individual duties in a participatory democracy is at least partly met through the forming of groups around important societal issues. Given the complex nature of political socialization, this study investigated identifiable determinants of social action that might be used to advantage in educating young people for citizenship in a democracy. This study attempted to differentiate among junior high, high school and college students (N=517) who were inclined and not inclined to act on their concerns about nuclear threat with selected demographic, psychological, political, and educational variables. The results of a discriminant functional analysis indicated that in comparison with the non-action group, students in the action group were characterized by reporting less trust in government, more exposure to sources of nuclear war information, more political ...
The Predictive Capability Maturity Model (PCMM) is a new model that can be used to assess the level of maturity of computational modeling and simulation (M&S) efforts. The development of the model is based on both the authors experience and their analysis of similar investigations in the past. The perspective taken in this report is one of judging the usefulness of a predictive capability that relies on the numerical solution to partial differential equations to better inform and improve decision making. The review of past investigations, such as the Software Engineering Institute's Capability Maturity Model Integration and the National Aeronautics and Space Administration and Department of Defense Technology Readiness Levels, indicates that a more restricted, more interpretable method is needed to assess the maturity of an M&S effort. The PCMM addresses six contributing elements to M&S: (1) representation and geometric fidelity, (2) physics ...
Nine infants (six boys, three girls) with anorectal anomalies were examined in the immediate newborn period, prior to corrective surgery, with MRI. Three high, one intermediate and five low anomalies were found at MRI - one patient with a `low` lesion was subsequently found at surgery 2 months later to have a high anorectal anomaly. This infant had passed meconium per urethram soon after the MRI study, prompting the need for a protective colostomy and stressing the importance of a thorough clinical examination of babies with anorectal malformations. The MRI results and findings at surgery were in agreement in all other patients (n=8). Hydronephrosis was evident in two and renal agenesis in one patient. Sacrococcygeal hypoplasia was found in two and two hemivertebrae in one infant. No spinal cord lesion was identified. One fistula was evident on MRI but four were later found at surgery. Uniformly hyperintense T1 signal meconium was seen in all nine newborns, ...
Salamanders regenerate their appendages after amputation and nerves are required for this process. Experiments were designed to test the idea that one way nerves could affect blastema cell proliferation is by influencing the metabolism of extracellular matrix (ECM) components and to identify neurotrophic factors which promote blastema cell mitosis. Temporal and spatial differences of glycosaminoglycans (GAGs) synthesis is innervated and denervated limbs were examined. Hyaluronic acid (HA) was found to be the major GAG produced during the proliferative period and chondroitin sulfate during differentiation. Denervation reduced synthesis of both these components by half. Dorsal root ganglia and fibroblast growth factor (FGF), a brain-derived mitogen, similarly doubled GAG synthesis in cultured blastemas, the FGF-effect being primarily on HA production. Histochemical and autoradiographical results confirmed the biochemical data. Autoradiography of ...
In a vacuum insulator, the narrow electron beam emitted from the cathode impinges on the anode and raises its temperature and also may produce high thermal stress. This high thermal stress, in conjuction with the surface electrostatic pressure may rupture the surface and detach particles from it. In this thesis, the interaction of high energy electron and laser beams with metals and semiconductors is investigated. The differential equations governing the physical processes involved in the interaction are solved by the finite element method. Effects of beam penetration into the material, variable beam reflectance at the surface, finite beam size and dependence of material properties on temperature are accounted for. The two-phase moving boundary problem, also known as the Stefan problem, is solved by an enthalpy formulation of the heat equation. Material deformation by thermal stresses caused by high temperature gradients and electrostatic forces induced by space ...
The X-band EPR spectra of unirradiated and "6"0 Co gamma ray irradiated cardamom (Elettaria cardamomum L. Maton, Zingiberaceae), ginger ((Zingiber officinale Rosc., Zingiberaceae), saffron (Crocus sativus L., Iridaceae), and curry have been investigated at room temperature. All unirradiated spices presented a weak resonance line with g-factors around free-electron ones, most probably due to the presence of semiquinones, previously reported to have paramagnetic properties. After gamma ray irradiation at absorbed dose up to 11.3 kGy we have noticed in all spices the presence of complex EPR spectra consisting of a superposition of at last two different paramagnetic species whose amplitude increase monotonously with the absorbed dose. A 100 deg. C isothermal annealing of 11.3 kGy irradiated samples has shown a differential reduction of amplitude of various components that form the initial spectra, but even after 5 h of thermal treatment, the remaining amplitude ...
The automotive paints could be generally differentiated by color, layer sequence and chemistry of the paint layers comprising each of the topcoat and the primer system. The successful identification of hit-and-run a and traffic accidental vehicles from evidential paint fragments is greatly facilitated with a comprehensive laboratory collection of reference paint samples and the technique for direct analysis without sample preparation. The Pyrolysis-Gas Chromatography(PGC) is a precise and reliable method for performing both quantitative and qualitative analysis of polymeric materials and forensic samples. Our Forensic Laboratory is conducting the examination and identification of 73 reference paint samples; 4 colors of each domestic automotive make that is poplar in Korea, by Curie Point Pyrolyzer(JHP-3) and GC with capillary column(ultra alloy-5). This method can be used not only to compare paint traces with their suspected sources, but also to ...
The ras oncogenes function by indirectly controlling expression of a subset of yet-undefined genes that are crucial for cell growth and differentiation. In a differential display strategy, numerous...Full Text Available
There is a requirement for a noninvasive technique to monitor stem cell differentiation. Several candidates based on optical spectroscopy are discussed in this review: Fourier transform infrared (FTIR)...Full Text Available
BackgroundThrough differentiation processes, keratinocytes provide a physical barrier to our bodies and control skin features such as moisturization, wrinkles and pigmentation. Keratinocyte...Full Text Available
The main purposes of this research was to investigate the feasibility of incineration of wool-scouring sludge in a novel vertical-axis-rotating fluidised bed (RFB). The experiment was carried out in a RFB with an internal diameter (ID) of 200 mm and height of 50 mm. A cold test was first conducted to investigate the fluidization performance of the RFB via parameters such as the bubbling, gas distribution, bed shape and pressure drop. The tumbling phenomena was observed in the bed, and this effectively enhanced the axial mixing. The appropriate range of bed thickness, rotating speed and sand particle size were identified to ensure the full fluidization and reduce the particle elutriation. Four wool-scouring sludges from different processes were incinerated in the RFB. With 5% support methane, all sludges with a maximum moisture up to 70% as received could be successfully burned in the RFB at rotating speeds of 200 and 300 rpm. The combustion was found to be intense ...
Tachycardia Detection, ICD, CRT-D Devices, Appropriate and Inappropriate Shock.-Introduction: We evaluated the frequency of appropriate and inappropriate shocks and survival in patients using dual-zone programming versus single-zone programming. Methods and Results: For the ALTITUDE REDUCES study, patients were followed for 1.6 1.1 years. The 12-month incidence of any shock was lower for dual-versus single-zone programmed detection at rates -170 bpm and between 170-200 bpm (P < 0.001). Appropriate shock rates at 1 year were also lower with dual-zone programming in these rate intervals (single zone 9.1%, 5.4%, P < 0.001, dual zone 6.7%, 4.7%, P < 0.02). There were no detectable differences between single- and dual-zone shock incidence at detection rates - 200 bpm (P = 0.14). Inappropriate s...
This study was designed to identify abnormalities in the hepatic-arterial/portal-venous scintiangiogram (SA) in alcoholic hepatitis (AH). SA's were performed in 35 patients with acute alcoholic hepatitis (AAH), 8; acute alcoholic hepatitis superimposed on cirrhosis (A/C), 14; and cirrhosis (C), 13. Posterior flows were done with a bolus of 10 mCi Tc-99m sulfur colloid with computer time-activity curves over the liver and left kidney. Curves were analyzed for per cent of hepatic arterial (HA) and portal venous contribution using the slope ratio method. Hepatic arterialization was estimated from the angle of the HA component of the curve. Reversal of the relative contribution of the hepatic and portal components of total flow were seen in all groups. Although quite severe in AH, the degree of reversal could not be used to differentiate among the groups. The average HA angle in AAH was 48.3 +- 8.1, in A/C 41.5 +- 10.6, and in C 30.4 +- ...
This study was designed to identify abnormalities in the hepatic-arterial/portal-venous scintiangiogram (SA) in alcoholic hepatitis (AH). SA's were performed in 35 patients with acute alcoholic hepatitis (AAH), 8; acute alcoholic hepatitis superimposed on cirrhosis (A/C), 14; and cirrhosis (C), 13. Posterior flows were done with a bolus of 10 mCi Tc-99m sulfur colloid with computer time-activity curves over the liver and left kidney. Curves were analyzed for per cent of hepatic arterial (HA) and portal venous contribution using the slope ratio method. Hepatic arterialization was estimated from the angle of the HA component of the curve. Reversal of the relative contribution of the hepatic and portal components of total flow were seen in all groups. Although quite severe in AH, the degree of reversal could not be used to differentiate among the groups. The average HA angle in AAH was 48.3 +- 8.1, in A/C 41.5 +- 10.6, and in C 30.4 +- 12.1. In ...
The Mizunami Underground Research Laboratory (MIU) of the Japan Atomic Energy Agency is a major site for geoscientific research to advance the scientific and technological basis for geological disposal of high-level radioactive waste in crystalline rock. Studies on relevant engineering technologies in the MIU consist of a) research on design and construction technology for very deep underground applications, and b) research on engineering technology as a basis of geological disposal. In the Second Phase of the MIU project (the construction phase), engineering studies have focused on research into design and construction technologies for deep underground. The main subjects in the study of very deep underground structures consist of the following: 'Demonstration of the design methodology', 'Demonstration of existing and supplementary excavation methods', 'Demonstration of countermeasures during excavation' and 'Demonstration of safe construction'. In the FY 2007 studies, identification ...
11-MeV neutrons were elastically and inelastically scattered from eight single-closed-shell nuclei: three proton-vibrational nuclei with N = 50 ("8"8Sr, "9"0Zr, "9"2Mo) and five even-even neutron-vibrational nuclei ("1"1"6"-"1"2"4Sn) with Z = 50. Detection methods involving electronic discrimination against #gamma# rays, and time-of-flight techniques were used to measure the energy of the scattered neutrons. Data were taken from 15"0 to 150"0 in 5"0 intervals. Measured differential cross sections were normalized to the zero-degree neutron flux and corrected. An optical model (OM) analysis was used to fit the elastic data with the code GENOA, and potential parameters were obtained for each nucleus. The observed low-lying electric quadrupole (2"+) and octupole (3"-) states were collective in nature; the macroscopic or collective model for inelastic scattering was used to generate the differential cross-section angular distributions with the ...
Receptor interacting protein 140 (RIP140) is a coregulator for numerous nuclear receptors and transcription factors and primarily exerts gene-repressive activities on various target genes. We previously identified a spectrum of posttranslational modifications on RIP140 that augment its property and biological activity. In T(3)-triggered biphasic regulation of cellular retinoic acid binding protein 1 (Crabp1) gene along the course of fibroblast-adipocyte differentiation, we found TRAP220(MED1) critical for T(3)-activated chromatin remodeling whereas RIP140 essential for T(3)-repressive chromatin remodeling of this gene promoter. In this current study, we aim to examine whether and how RIP140 replaces TRAP220(MED1) on the CrabpI promoter in differentiating adipocyte cultures. We find increasing recruitment of RIP140 to this promoter, with corresponding reduction in TRAP220(MED1) recruitment during the T(3)-repressive phase. ...
Background: Recent studies have developed a murine model of IgE-mediated food allergy based on oral coadministration of antigen and cholera toxin (CT) to establish a maximal response for studying immunopathogenic mechanisms and immunotherapeutic strategies. However, for studying subtle immunomodulating factors or factors effective during response initiation, this maximal response-based model is less suitable due to a lack of sensitivity. Therefore, in attempts to identify essential parameters to fine-tune the immune response towards a submaximal level, potentially more sensitive, we were interested in characterizing the individual effects of the parameters in the CT-based model: CT dose, antigen type and dose, and number of immunizations. Methods: BALB/c mice were orally sensitized weekly for 3 or 7 weeks with graded doses of CT and various food antigens (soy-trypsin inhibitor, ovalbumin or ovomucoid). Antigen-specific lgG1, IgG2a, IgA and IgE were monitored by ...
Within the Williston basin, thickness variations of the Prairie Formation are common and are interpreted to originate by two processes: differential accumulation of salt during deposition and differential removal of salt by dissolution. Unambiguous evidence for each process is rare because the Prairie/Winnipegosis interval is seldom cored within the US portion of the basin. Therefore, indirect methods, using well logs, provide the principal method for identifying characteristics of the two processes. The results of this study indicate that the two processes can be distinguished using correlations within the Prairie Formation. Several regionally correlative brining-upward and probably shoaling-upward sequences occur within the Prairie Formation. Near the basin center, the lowermost sequence is transitional with the underlying Winnipegosis Formation. This transition is characterized by thinly laminated basal carbonates that ...
The paper presents cloud structure models for Jupiter's Great Red Spot, Equatorial and North Tropical Zones, North and South Temperate Zones, and North and South Polar Regions. The models are based on images of Jupiter in three methane bands and nearby continuum radiative transfer calculations include multiple scattering and absorption from three aerosol layers. The model results include the transition in the upper-cloud altitude to 3 km lower altitude from the tropical zones to temperate zones and polar regions, a N/S asymmetry in cloud thickness in the tropical and temperature zones, and the presence of aerosols up to about 0.3 bar in the Great Red Spot and Equatorial Zone. It is concluded that polarization data are sensitive to aerosols in and above the upper cloud layer but insensitive to deeper cloud structure.
This article aims to open up the biographical black box of three experts working in the boundary zone between science, policy and public debate. A biographical-narrative approach is used to analyse...Full Text Available
Neuroblasts born in the adult subventricular zone (SVZ) migrate long distances in the rostral migratory stream (RMS) to the olfactory bulbs where they integrate into circuitry as functional interneurons....Full Text Available
Several low-mass models with an inhomogeneous radiative core and a convective envelope are investigated, the entire core or its upper portion being treated as a zone of neutral stability. Mixing by convective overshoot will then give rise to unstable structure.
KOREA-JAPAN NUCLEAR WEAPON FREE ZONE (KJNWFZ) CONCEPT PAPER ...A Korea-Japan2 Nuclear Weapon Free Zone (hereafter KJNWFZ) is a new concept.Once realized, ...Finally, we outline the key elements of the Korea-Japan NWFZ proposed in this paper, noting
The paper presents a review of the current state of knowledge on the likely impacts of extreme weather and climate events on coastal zones and small islands in the context of climate change. Possible response options, including prevention, preparedness and adaptation, are indicated.
The destiny of the mitotically active cells of the subventricular zone (SVZ) in adult rodents is to migrate to the olfactory bulb, where they contribute to the replacement of granular and periglomerular...Full Text Available
The aim of this study was to investigate the effect of erythropoietin (EPO) on histological brain injury, subventricular zone (SVZ) expansion, and sensorimotor function deficits induced by hypoxia-ischemia...Full Text Available
Small-angle X-ray scattering method recognised to be very useful in the studies of structural problems of materials in homogeneous in nanoscale. Studies by small-angle X-ray scattering on the Al-Ag alloys are presented. The size distributions of spherical Guinier-Person zones were calculated using Vonk's and Glatter's methods. Small-angle X-ray scattering studies were performed on Al-5.0 at.%Ag alloy containing Guinier-Preson zones in the #eta#-state. For this alloy one can assume that scattering particles are of spherical shape, have uniform electron density and scatter independently. Moreover, the size distributions were calculated for Al-1.6 at.%Ag alloy containing Guinier-Preston zones in #epsilon#-state (scattering particles with not uniform electron density). Both, Vonk's and Glatter's, methods gave similar size distributions. Profiles of size distributions for Guinier-Preston zones in ...
The biological and radiobiological peculiarities of seeds and seedlings of the Rumex confertus and Lupinus polycolor plants, which grown during several generations in plots with different level of radionuclide pollution of the Chernobyl exclusive zone have been investigated.
A simulation is developed that qualitatively describes the small-zone-gel-filtration behaviour of a reversibly associating protein. The results reflect the dependence of the apparent molecular weight...Full Text Available
Chronic autoimmune or pathogen-induced immune reactions resulting in lymphoid neogenesis are associated with development of malignant lymphomas, mostly extranodal marginal zone B-cell lymphomas (MZBCLs)....Full Text Available
Biodegradable and green plastics are the new tendency in the world. The effect of the electron beam irradiation in aromatic aliphatic copolyester and the blend with corn starch films (Ecoflex{sup R} and Ecobras{sup R}) were studied by tensile strength at break, elongation at break, Scanning Electronic Microscopy (SEM), Fourier Transform Infrared Spectroscopy (FT-IR), Differential Scanning Calorimetry (DSC), crosslinking degree and biodegradability. The measurements in both, the machine direction and the transverse direction were made for mechanical tests. It was found that, the electron irradiation caused an increase in the strength at break of the blend with corn starch film, when doses of up to 10 kGy were applied. A significant decrease of the elongation at break of the blend with corn starch was observed at doses of 10 kGy and 40 kGy. It was not found important change in tensile properties for aromatic aliphatic copolyester. Structural changes of the samples ...
Biodegradable and green plastics are the new tendency in the world. The effect of the electron beam irradiation in aromatic aliphatic copolyester and the blend with corn starch films (Ecoflex"R and Ecobras"R) were studied by tensile strength at break, elongation at break, Scanning Electronic Microscopy (SEM), Fourier Transform Infrared Spectroscopy (FT-IR), Differential Scanning Calorimetry (DSC), crosslinking degree and biodegradability. The measurements in both, the machine direction and the transverse direction were made for mechanical tests. It was found that, the electron irradiation caused an increase in the strength at break of the blend with corn starch film, when doses of up to 10 kGy were applied. A significant decrease of the elongation at break of the blend with corn starch was observed at doses of 10 kGy and 40 kGy. It was not found important change in tensile properties for aromatic aliphatic copolyester. Structural changes of the samples ...
Gas storage is a critical element in the natural gas industry. Producers, transmission and distribution companies, marketers, and end users all benefit directly from the load balancing function of storage. The unbundling process has fundamentally changed the way storage is used and valued. As an unbundled service, the value of storage is being recovered at rates that reflect its value. Moreover, the marketplace has differentiated between various types of storage services and has increasingly rewarded flexibility, safety, and reliability. The size of the natural gas market has increased and is projected to continue to increase towards 30 trillion cubic feet over the next 10 to 15 years. Much of this increase is projected to come from electric generation, particularly peaking units. Gas storage, particularly the flexible services that are most suited to electric loads, is crucial in meeting the needs of these new markets. To address the gas storage needs of the ...
Because of the chaotic nature of the corrosion process and the complexity of the electrochemical noise signals that are generated, there is no generally accepted method of measuring and interpreting these signals that allows the consistent detection and identification of sustained localized pitting (SLP) as compared to general corrosion. We have reexamined electrochemical noise analysis (ENA) of localized corrosion using different hardware, signal collection, and signal processing designs than those used in conventional ENA techniques. The new data acquisition system was designed to identify and monitor the progress of SLP by analyzing the power spectral density (PSD) of the trend of the corrosion current noise level (CNL) and potential noise level (PNL). Each CNL and PNL data point was calculated from the root-mean- square value of the ac components of current and potential fluctuation signals, which were measured simultaneously during a short time period. The PSD ...
Besides differentiation and apoptosis, cell migration is a basic process in brain development in which neural cells migrate several centimeters within the developing brain before reaching their proper positions and forming the right connections. For identifying signaling events that control neural migration and are therefore potential targets of chemicals to disturb normal brain development, we developed a human neurosphere-based migration assay based on normal human neural progenitor (NHNP) cells, in which the distance is measured that cells wander over time. Applying this assay, we investigated the role of the extracellular signal-regulated kinases 1 and 2 (ERK1/2) in the regulation of NHNP cell migration. Exposure to model substances like ethanol or phorbol 12-myristate 13-acetate (PMA) revealed a correlation between ERK1/2 activation and cell migration. The participation of phospho-(P-) ERK1/2 was confirmed by exposure of the cells to the ...
...Benthic Marine Bioregionalisation of Australia's Exclusive Economic Zone The benthic (sea floor) component of the National Marine Bioregionalisation covers the 80% of Australia's ... Exclusive Economic Zone that lies beyond the continental shelf break. It provides a description of patterns of biological distributions and physical habitats on the seafloor....sea floor) component of the National Marine Bioregionalisation covers the 80% of Australia's Exclusive Economic Zone that lies beyond the continental shelf break. It provides a ... Benthic Marine Bioregionalisation of Australia's Exclusive Economic Zone Change text size Skip to content Marine Bioregional Planning resources Search: About us Contact us You ...
In this review, we demonstrate the developmental appearance, structural features, and reorganization of transient cerebral zones and structures in the human fetal brain using a correlative histological and MRI analysis. The analysis of postmortem aldehyde-fixed specimens (age range: 10 postovulatory weeks to term) revealed that, at 10 postovulatory weeks, the cerebral wall already has a trilaminar appearance and consists of: (1) a ventricular zone of high cell-packing density; (2) an intermediate zone; (3) the cortical plate (in a stage of primary consolidation) with high MRI signal intensity. The anlage of the hippocampus is present as a prominent bulging in the thin limbic telencephalon. The early fetal telencephalon impar also contains the first commissural fibers and fornix bundles in the septal area. The ganglionic eminence is clearly visible as an expanded continuation of the proliferative ventricular ...
In the course of designing a catalytic porous membrane reactor for experimental studies, both inside and outside of the non-reaction zones as well as the two ends of the membrane need to be completely sealed to ensure that there is no flow across the membrane in the non-reaction zone. Experiments show that up to 50% of the total flow across the membrane may be contributed by the axial flow along the wall of the non-reaction zones if only one side of the membrane is sealed. Another problem that cannot be solved by sealing is the capillary flow of the catalyst along the tube wall into the non-reaction zones when the catalyst is doped on the membrane. One of the best ways to avoid this axial flow of catalyst would be to use non-porous tubes in the non-reaction zones and join them with the porous membrane tube. In doing so, the cost of the membrane reactor could be reduced simply ...
A photoacoustic (PA) imaging system based on an ultrasonic Fresnel zone plate (FZP) transducer is developed for the purpose of imaging biological tissue. This FZP transducer has a two-zone negative zone plate piezoelectric material pattern, and an optical fibre is integrated with the transducer on the symmetric axis of the zone plates to deliver laser pulses to the sample. The focal characteristic of the FZP transducer is analysed by theoretical prediction and experimental measurement, and the measured results are in good agreement with the predicted results. The limited-field back-projection deconvolution algorithm combined with the coherence-factor weighting technique is used to reconstruct the optical absorption distribution. The experiments were performed with phantoms and the blood vessels of chicken embryo chorioallantoic membrane. The results demonstrate that PA imaging using the FZP transducer ...
Microstructure and properties of a Mg AZ31B laser beam weld without filler are studied using electron microscopy, X-ray diffraction and mechanical tests. The microstructure of the weld is characterized by a narrow heat affected zone, columnar grains and precipitate coarsening in the fusion zone. Texture in the fusion zone is significantly different from the texture of the base material. The residual stress distribution observed is similar at the top and the bottom of the weld, maximum tensile residual stress values are observed in the fusion zone. Tensile tests reveal differences in the mechanical behavior of the fusion zone and the parent material, which can be related to the differences of texture and the resulting deformation mechanisms.
Pursuant to statement issued by the Government of Vietnam on 12 May 1977, on the territorial sea, the contiguous zone, the exclusive economic zone (EEZ) and the continental shelf of Vietnam, and according to the provisions of the LOS Convention, the EEZ of Vietnam extends principally up to 200NM from the baseline, and the area of EEZ amounts to about one million square km including the Hoang Sa (Paracel) and Truong Sa (Spratly) Islands [The declaration of the Government of Vietnam on the territorial sea, contiguous zone, exclusive economic zone and continental shelf, Hanoi, 1977]. The establishment of EEZ has significantly changed circumstances for the fisheries sector in Vietnam.Recently, even though the adaptation of new techniques and technologies to the fisheries sector has been somewh...
The reactor core of TAPP-3 and 4 is divided into 14 power zones for spatial power control. Corresponding to each zone is a light water zonal compartment. The 14 ZCCs are located in two radial planes, each containing 7 ZCCs. For each zone, power measurement is carried out using three cobalt Self Powered Neutron Detectors (SPNDs) at appropriate locations close to the respective ZCC. Since the zone power as obtained by the true average of the healthy zone control detector (ZCD) readings belonging to a particular zone may not correspond to its actual power because these 3 detectors per zone, measure only point fluxes but the zone extends over a large core region. Therefore accurate estimation of zone power calibration factors is required to estimate the zone powers and also to ...
In the heat-affected zones (HAZ) of low alloy steels used for nuclear pressure vessel, microstructural changes, such as grain coarsening, carbide precipitation, and martensite formation, generally occur and cause a deterioration of toughness and an increase in sensitivity to brittle fracture. Metallographic analyses of low alloy steel welds reveal significantly different regions in HAZ microstructures. In 2-pass welds, there were seven characteristic regions in the HAZ determined by the peak temperature, to which the region was exposed during the weld thermal cycle: a coarse-grained region, a fine-grained region, an intercritical region, and subcritical region. The coarse-grained region can be categorized into four zones according to the reheating temperature as follows : an unaltered coarse-grained zone (UCGHAZ), a supercritically reheated coarse grained zone (SCRCGHAZ), an intercritically reheated ...
The recent breakthrough in the generation of rat embryonic stem cells (rESCs) opens the door to application of gene targeting to create models for the study of human diseases. In addition, the in vitro differentiation system from rESCs into derivatives of three germ layers will serve as a powerful tool and resource for the investigation of mammalian development, cell function, tissue repair, and drug discovery. However, these uses have been limited by the difficulty of in vitro differentiation. The aims of this study were to establish an in vitro differentiation system from rESCs and to investigate whether rESCs are capable of forming terminal-differentiated cardiomyocytes. Using newly established rESCs, we found that embryoid body (EB)-based method used in mouse ESC (mESC) differentiation...
Tidally dominated sections from the Middle Jurassic Beryl Formation of the Beryl Field, Viking Graben (UKCS) were deposited during rapid changes in relative sea level. High density well coverage in this key producing interval has allowed the construction of an integrated high resolution sequence stratigraphic scheme based on sedimentological, ichnofaunal, wireline, biostratigraphic and engineering data. From this database a number of high resolution sequences in the Bajocian-Bathonian Beryl Formation have been identified composed of interbedded sandstones, siltstones and mudstones. These sediments formed tidally-influenced deltas and estuaries deposited in actively subsiding half-grabens during regionally extensive base-level changes. For reservoir management purposes, the formation has been split into 5 units. The thickest interval, Unit 3, is considered here. In the northern part of the Beryl Field, Unit 3 is bounded above and below by regionally extensive, ...
The authors have interpreted 1,400 km of industry and government multichannel seismic reflection data from eastern Lake Superior. Seismic sequences have been identified by using reflection character and reflector terminations and truncations. This framework, coupled with outcrop information, has allowed them to assign lithologic units to some of these reflectors and reconstruct the timing and geometry of structures within the basin. The authors have mapped the Base Jacobsville-Bayfield Group/Top oronto Group, Base oronto Group/Top Keweenawan volcanics, and Basement as well as several reflectors internal to these groups. Integration of gravity and magnetic data with the seismic grid permits regional mapping of faults and folds between seismic lines. In the eastern part of the basin, high-angle basement-involved reverse faults, such as the southeastern combination of the Keweenaw fault, trend NNW-SSE, while broad folds trend E-W. The Keweenaw fault is a complex ...
A process model is presented and used for identifying options for controlling the cupola furnace process and for investigating natural gas substitutes. Fuel substitution will affect temperature curves (i.e. tapping temperatures and melting capacity), outlet temperatures and gas mass flow out of the preheating zone. The contribution presents several process variations to overcome these problems and compares them with the natural gas process. [German] Mit dem Prozessmodell werden zunaechst Moeglichkeiten der Steuerung von Abstichtemperatur und Schmelzleistung, insbesondere unter Beruecksichtigung der Schrottqualitaet (spezifische Oberflaeche a{sub G}), untersucht. Es wird gezeigt, dass das Prozessmodell die Ergebnisse aus der Praxis wiedergibt. Daran anschliessend wird mit dem Prozessmodell die Substitution von Erdgas durch minderwertige Gase untersucht (Brennstoffsubstitution, Ressourcenschonung). Durch die Brennstoffsubstitution veraendern sich ...
The first radon soil gas survey in Serbia, using passive detectors (SSNTD, CR-39), was carried out in June 2005 at field sites in Niska Banja town. The aim of the survey was to identify risk zones characterised by high levels of this radioactive gas. Radon measurements were made at the depth of 50 cm, in the ground according to a systematic grid pattern. Furthermore, at all 48 measurement points, the surface gamma dose rates in the air was also measured at the same locations and soil samples were collected for gamma spectrometric analysis for the radionuclides {sup 226}Ra, {sup 228}Th and {sup 40}K. Radon concentrations were found to range from 1270 to 155000Bqm{sup -3} with an average of 33765Bqm{sup -3} and a median value of 12626Bqm{sup -3}. The geometrical mean value and geometrical standard deviation were calculated as 16160Bqm{sup -3} and 3.5Bqm{sup -3}, respectively. Gamma dose rate varies from 92 to 316nGyh{sup -1}, with an average of ...
The first radon soil gas survey in Serbia, using passive detectors (SSNTD, CR-39), was carried out in June 2005 at field sites in Niska Banja town. The aim of the survey was to identify risk zones characterised by high levels of this radioactive gas. Radon measurements were made at the depth of 50 cm, in the ground according to a systematic grid pattern. Furthermore, at all 48 measurement points, the surface gamma dose rates in the air was also measured at the same locations and soil samples were collected for gamma spectrometric analysis for the radionuclides "2"2"6Ra, "2"2"8Th and "4"0K. Radon concentrations were found to range from 1270 to 155000Bqm"-"3 with an average of 33765Bqm"-"3 and a median value of 12626Bqm"-"3. The geometrical mean value and geometrical standard deviation were calculated as 16160Bqm"-"3 and 3.5Bqm"-"3, respectively. Gamma dose rate varies from 92 to 316nGyh"-"1, with an average of 132nGyh"-"1. The radium content in ...
Purpose: Liposarcoma is the most common soft tissue sarcoma in adults. The purpose of the study was to correlate MR imaging features with the four ICD subclasses. Methods: 28 patients with liposarcoma were examined preoperatively on a 1.0 T MRI system, using spin echo sequences, gradient echo imaging and STIR sequences. In all patients, classification of the liposarcomas was made by histologic diagnosis (ICD-10-M-classification). Results: Well differentiated liposarcomas (9 patients) showed a number of MRI features consistent with lipoma (well defined mass high signal intensity (SI) on T{sub 1} images, low signal on T{sub 2} images, no or only little signal increase of tumour tissue after contrast material application, no necrosis). Not well differentiated liposarcomas (myxoid 14 patients, pleomorphic three patients, round cell two patients) revealed the largest part of the mass to be of low SI on T{sub 1}-weighted images. Only scattered fatty ...
This presentation described the geology of the Kootenay, Gething, Gates, Brazeau and Coalspur Formations in the potential gas-bearing coal zones of the Alberta Foothills/Mountains. The future potential of this region for coalbed methane (CBM) exploitation was discussed, based on available data from drilling activity and the results of a recent coal desorption and adsorption study in the Val d'Or seam of the Coalspur formation. The gas content of the 5 coal zones was evaluated and compared with previous CBM exploration in the area. For evaluation purposes, the coal zones were divided into shallow and deep coal zones. The potential gas content of the shallow coal zones is approximately 31 Tcf of CBM. This is considered an inferred, initial, in-place, CBM resource estimate based on limited data. The gas content of deep zones is approximately 99 Tcf of ...
Coal is present in the Alberta Foothills/Mountains in five zones: the Kootenay, Gething, Gates, Brazeau and Coalspur coal zones. For coalbed-methane (CBM) evaluation purposes, they can be divided into shallow (less than 1000 m depth) and deep (greater than 1000 m depth) coal zones. The potential gas content of all shallow coal zones totals about 878x10{sup 9} m{sup 3} (31 Tcf) of CBM, which is considered an inferred, initial, in-place, coalbed-methane resource estimate based on limited data. The limited amount of data on formation testing and measured gas content indicate that the inferred resource is bordering on the speculative category. The gas content of all deep coal zones (deeper than 1000 m) totals 2.8x10{sup 12} m{sup 3} (about 99 Tcf) of in-place coalbed-methane gas. Consequently, the total ultimate coalbed-methane resource could be 3.7x10{sup 12} m{sup 3} (130 Tcf). ...
This report describes the geology of the following 5 Alberta Foothills/Mountains coal zones: the Kootenay, Gething, Gates, Brazeau and Coalspur coal zones. The coal areas were assessed for gas content and compared with previous coalbed methane (CBM) exploration in the area. The coal zones can be divided into shallow (less than 1000 m depth) and deep (greater than 1000 m depth) coal zones for evaluation purposes. The potential gas content of the shallow coal zones is approximately 31 Tcf of CBM. This is considered an inferred, initial, in-place, CBM resource estimate based on limited data. The gas content of deep zones is approximately 99 Tcf of in-place CBM gas. Therefore, the total ultimate CBM resource is estimated at 130 Tcf. CBM recovery is not usually attempted due to high drilling costs and low permeability. The only CBM production from the Foothills has ...
AIM: To investigate the effects of transforming growth factor β1 (TGF-β1) on the differentiation of colonic lamina propria fibroblasts (CLPF) into myofibroblasts in vitro.METHODS:...Full Text Available
In honor of the 50th anniversary of the “organizational hypothesis,” this paper reviews work on sexual differentiation of the spinal cord and peripheral nervous system....Full Text Available
Totipotent stem cells have the potential to differentiate into every cell type. Renewal of totipotent stem cells in the germline and cellular differentiation during early embryogenesis rely upon posttranscriptional...Full Text Available
AIM: To investigate differential points of solid-pseudopapillary neoplasm (SPN) of the pancreas and pancreatic endocrine tumor (PET).METHODS: Ten cases of SPN and fourteen cases of PET were studied...Full Text Available
Mice and rats are important mammalian models in biomedical research. In contrast to other biomedical fields, work on sexual differentiation of brain and behavior has traditionally utilized comparative...Full Text Available
SummaryBecause increasing numbers of HIV vaccine candidates are being tested globally, it is essential to differentiate vaccine-from virus-induced antibodies. Most of the currently...Full Text Available
For a simplicial manifold we construct the differential geometry structure and use it to investigate linear connections, metric and gravity. We discuss and compare three main approaches and calculate the resulting gravity action functionals. (author)
Background: Squamous differentiation/squamous metaplasia is often associated with endometrial adenocarcinoma and benign lesions, such as endometrial hyperplasia and chronic endometritis....Full Text Available
BackgroundCavernous hemangiomas are the most frequent neoplasms of the liver and in routine clinical practice they often need to be differentiated from malignant tumors and other...Full Text Available
Osteoblasts are the primary cells responsible for bone formation. They also support osteoclast formation from bone marrow precursors in response to osteotropic factors by inducing receptor activator...Full Text Available
This book provides differential diagnostic possibilities of specific scan abnormalities in one volume for easy reference. This book is organized by organ systems and covers the central nervous system, the endocrine, skeletal, pulmonary, gastrointestinal, genitourinary, and cardiovascular systems. The gamuts are designed to teach differential diagnosis and to assist in the actual interpretation of patient slides.
Experimental techniques are presented that can be used to assay and correct for differential light scattering effects in circular dichroism spectra of biological macrostructures. The assay is based...Full Text Available
Genome endoreduplication during mammalian development is a rare event for which the mechanism is unknown. It first appears when fibroblast growth factor 4 (FGF4) deprivation induces differentiation...Full Text Available
OBJECTIVE: The risk of cardiovascular and renal diseases has been shown to be higher for systolic blood pressure than diastolic blood pressure. The aim of this study was to assess the differential control...Full Text Available
In this paper, the following topics are studied: uranium 238 effective integral; thermal range uranium 238 capture cross section; Americium 242 m capture cross section. The mentioned examples show that differential and integral experiments are both useful...
We have investigated the usefulness of ribotyping for the differentiation of aeromonads isolated from five patients with gastroenteritis and from the source water, treatment plant, and distribution...Full Text Available
Manganous chloride and Congo red incorporated into blotting paper discs have been used to differentiate gonococci from meningococci. The new technique is simple and reliable; the materials for the test...Full Text Available
This paper deals with the indications for prostatectomy; the differential diagnosis of the symptomatology of bladder neck obstruction; and the factors influencing the choice of operation....Full Text Available
Spline functions associated with a general linear differential operator L which interpolate prescribed data with respect to arbitrary linear functionals are investigated. (Author)
In this paper, we study the existence and uniqueness of periodic solutions of the differential equation of the form . Here, we obtain some sufficient conditions which guarantee the existence of periodic solutions. This equation is a quite general third- order nonlinear vector differential equation, and one example is given for illustration of the subject.
An x-ray zone plate was fabricated using the novel approach of focused ion beam (FIB) milling. The FIB technique was developed in recent years, it has been successfully used for transmission electron microscopy (TEM) sample preparation, lithographic mask repair, and failure analysis of semiconductor devices. During FIB milling, material is removed by the physical sputtering action of ion bombardment. The sputter yield is high enough to remove a substantial amount of material, therefore FIB can perform a direct patterning with submicron accuracy. The authors succeeded in fabricating an x-ray phase zone plate using the Micrion 9500HT FIB station, which has a 50 kV Ga{sup +} column. Circular Fresnel zones were milled in a 1.0-{micro}m-thick TaSiN film deposited on a silicon wafer. The outermost zone width of the zone plate is 170 nm at a radius of 60 {micro}m. An achieved aspect ratio ...
Samples from a burning bituminous coal seam from Coalspur, Alberta, were studied by reflected light microscopy. Two zones - namely oxidation- combustion and distillation - were detected in the seam. Near the surface, the oxidation zone contained chars showing cracks and oxidation rims. The cracks were filled with fluorescing hydrocarbon material formed by thermal cracking of coal macerals. The chars in the deeper part of the oxidation zone had a carbonized matrix and burnt rims. The distillation zone covered most of the coal seam. Chars were mostly in the precarbonization stage, except those immediately below the combustion zone or near the base of the seam. Precarbonized chars contained pyrolytic carbon in some horizons. The distilled chars were formed by heat generated by combustion at the top of the seam and also by heat transfer from an underlying burning seam through an ...
Three blocks of non-welded tuff, one nominally one cubic foot (trial block) in volume and the other two, nominally one cubic meter (1 m3) in volume, were excavated from the Busted Butte Test Facility on the Nevada Test Site in 1999 and transported to the Atomic Energy of Canada Limited Whiteshell Laboratories in Pinawa, Manitoba. The trial block and one of the 1-m3 blocks were used for radionuclide migration experiments under unsaturated conditions; the remaining 1-m3 block was used for similar migration experiments under saturated conditions. After a vertical flow of synthetic transport solution was set up under unsaturated conditions, a suite of conservative and chemically reactive radionuclide tracers was injected at volumetric flow rates of 20 mL/hr in the trial block, and 10 mL/hr in two locations on the upper surface of the 1-m3 block. These flow rates correspond to infiltration rates of about 120 cm/year and about 17 cm/year, respectively. The duration of the migration ...
The Coalspur Formation is a continental succession of interbedded mudstone, siltstone and fine grained sandstone with subordinate coarser grained sandstone layers and channel lag deposits. Chert-pebble conglomerate (the Entrance conglomerate) occurs at the base of the formation, and coal beds interbedded with coaly shale and numerous thin bentonites occur in the upper part of the formation. An economically significant amount of high-quality thermal coal occurs within the upper, Paleocene part of the formation named the Coalspur coal zone. Coal from this zone, also known as the Coal Valley coal zone is being exploited in the Coal Valley Mine. 17 refs., 4 figs.
The contention of this commentary, focused on the vestibulocerebellum (particularly the flocculus), is that the great importance for our understanding of cerebellar organization in terms of climbing fiber zones, begun years ago by Voogd [1969, 2011] and Oscarsson [1969], needs to be matched by coming more to grips with the other fundamental geometrical organization of the cerebellum, the parallel fibers. The central issue is the selection of those parallel fiber signals to be transformed into Purkinje cell activity in the different zones. At present, in comparison to our knowledge of vestibulocerebellar climbing fiber inputs, the deficiencies in our knowledge of the zonal anatomy and physiology of vestibulocerebellar mossy fibers and granule cells are glaring. The recent emphasis on molecu...
We present a case of cerebral aspergillosis in an immunocompetent patient. The MRI signal characteristics were compared with the histologic findings. Irregular low-signal zones were demonstrated between the wall of the abscess and the central necrosis on T2-weighted images; the pathology specimen revealed concentrated iron in these transitional zones but no hemosiderin. Iron is an essential element for the growth of fungal hyphae. The low-signal zones may represent the areas where there was active proliferation of aspergillus, and the unique location of the low signal may be a helpful imaging characteristic for the diagnosis of an aspergillus abscess. (orig.)
The action of the Virasoro algebra on integrable hierarchies of non-linear equations and on related objects ('Schroedinger' differential operators) is investigated. The method consists in pushing forward the Virasoro action to the wave function of a hierarchy, and then reconstructing its action on the dressing and Lax operators. This formulation allows one to observe a number of suggestive similarities between the structures involved in the description of the Virasoro algebra on the hierarchies and the structure of conformal field theory on the world-sheet. This includes, in particular, an 'off-shell' hierarchy version of operator products and of the Cauchy kernel. In relation to matrix models, which have been observed to be effectively described by integrable hierarchies subjected to Virasoro constraints, I propose to define general Virasoro-constrained hierarchies also in terms of dressing operators, by certain equations which carry the information of the ...
In order to predict thermal hazards of high-energy materials, accurate kinetics constants must be determined. Predictions of thermal hazards for mixtures of high-energy materials require measurements on the mixtures, because interactions among components are common. A differential-scanning calorimeter (DSC) can be used to observe rate processes directly, and isothermal methods enable detection of mechanism changes. Rate-controlling processes will change as components of a mixture are depleted, and the correct depletion function must be identified for each specific stage of a complex process. A method for kinetics measurements on mixed explosives can be demonstrated with Composition B is an approximately 60/40 mixture of RDX and TNT, and is an important military explosive. Kinetics results indicate that the mator process is the decomposition of RDX in solution in TNT with a perturbation caused by interaction between the two components. It is ...
In the framework of spallation neutron sources and accelerator-driven systems, the international PISA (Proton-induced Spallation) collaboration has initiated measurements of total- and double-differential cross-sections for products of spallation reactions in a wide range of target nuclei (GU) at the COSY proton accelerator in Julich (Germany). The purpose is to study secondary particle production created in structural, window and target materials via proton beams up to 2.5 GeV of incident kinetic energy. Residual nuclei [H, He up to intermediate mass fragment (IMF)] production cross-sections are of great importance for estimating the damage to target and structure materials involving the planned spallation neutron sources, given that the lifetime of window and target materials is directly associated to those cross-sections. The demand for reliable theoretical predictions on production cross-sections is by no means satisfied by the models and codes that are ...
We present differential scanning calorimetry (DSC), X-ray diffractometry, in situ Moessbauer spectroscopy (MS), and transmission electron microscopy (TEM) studies in Metglas ribbons subjected to different heat treatments. The temperature evolution of the hyperfine field H_h_f(T) and the Curie temperature (T_c) of the amorphous phase are determined. The magnetic field originally present in the amorphous phase has a 'normal' behavior, in the sense that it can be described by the Weiss molecular field theory. The total angular momentum of the iron atoms turns out to be 5/2 and this implies Fe"3"+ in which the electronic spins are uncoupled. When the samples are maintained near T_c (#approx#673 K), three new magnetic phases are detected in the Moessbauer spectra, indicating an onset of a crystallization process well below the first crystallization temperature (T_X_1), as determined by DSC (#approx#820 K). The magnetic behavior of these phases is also described by ...
A balloon-borne instrument has measured the cosmic-ray antiproton flux between 130 and 320 MeV and searched for antihelium between 130 and 370 MeV per nuclear. These particles were selected from the background of normal-matter cosmic rays by combining a selective trigger with a detailed spark chamber visualization of each recorded event. Antiprotons are identified by their characteristic annihilatin radiation. Residue from background processes meeting the selection criteria is small. The observed 14 antiprotons yield a measured differential flux of 1.7 +- 0.5 x 10/sup -4/ antiprotons m/sup -2/ sr/sup -1/ s/sup -1/ MeV/sup -1/ at the top of the atmosphere. The corresponding antiproton/proton ratio is 2.2 +- 0.6 x 10/sup -4/,, only slightly smaller than the ratio observed by other experiments at higher energies. Thus the antiprotons have a spectral shape similar to the protons, at least down to about 100 MeV. The expected flux of these particles ...
The Anadenathera macrocarpa, Schinus molle, Hymenaea courbaril, Cariniana legalis, Solidago microglossa and Stryphnodendron barbatiman, were collected ''in natura'' samples (leaves, flowers, barks and seeds) from different commercial suppliers. The pharmaco-active compounds in ethanolic extracts had been made by the Mato Grosso Federal University (UFMT). The energy-dispersive x-ray fluorescence (ED-XRF) spectrometry was used for the elemental analysis in different parts of the plants and respective ethanolic extracts. The Ca, Cl, Cu, Fe, K, Mg, Mn, Na, Ni, P, Rb, S, Sr and Zn concentrations were determined by the fundamental parameters method. Some specimens showed a similar inorganic profile for ''in natura'' and ethanolic extract samples and some ones showed a distinct inorganic profile. For example, the Anadenathera macrocarpa showed a similar concentration in Mg, P, Cu, Zn and Rb elements in ...
IL-4-induced Stat6 signaling is active in a variety of cell types and plays a role in cell proliferation/growth and resistance to apoptosis. Using EMSA, we identifieddifferential IL-4/Stat6 activities in colorectal cancer cell lines, HT-29 being active Stat6"h"i"g"h phenotype and Caco-2 being defective Stat6"n"u"l"l phenotype, respectively. Active Stat6"h"i"g"h HT-29 cells exhibited resistance to apoptosis by flowcytometry and aggressive metastasis by Transwell assay compared with defective Stat6"n"u"l"l Caco-2 cells. Comparing one another using RT-PCR, Stat6"h"i"g"h HT-29 cells expressed more mRNA of anti-apoptotic and pro-metastatic genes Survivin, MDM2, and TMPRSS4, while Stat6"n"u"l"l Caco-2 cells expressed more mRNA of pro-apoptotic and anti-metastatic genes BAX, CAV1, and P53, respectively. This is the first study describing correlations of IL-4/Stat6 activities with apoptosis and metastasis in colon cancer. These findings, together with ...
The origin of the epithelial and myoepithelial cells in the human breast has not been delineated. In this study we have addressed whether luminal epithelial cells and myoepithelial cells are vertically connected, i.e., whether one is the precursor for the other. We used a primary culture assay allowing preservation of basic phenotypic traits of luminal epithelial and myoepithelial cells in culture. The two cell types were then separated immunomagnetically using antibodies directed against lineage-specific cell surface antigens into at best 100% purity. The cellular identity was ascertained by cytochemistry, immunoblotting, and 2-D gel electrophoresis. Luminal epithelial cells were identified by strong expression of cytokeratins 18 and 19 while myoepithelial cells were recognized by expression of vimentin and {alpha}-smooth muscle actin. We used a previously devised culture medium (CDM4) that allows vigorous expansion of proliferative myoepithelial cells and also ...
Candoxin (PDB #1JGK), a three-finger neurotoxin from Bungarus candidus venom, inhibits post-synaptic neuromuscular and neuronal alpha7nACh-receptors, and induces delayed cell-death throughout the glial population. When applied to cultured human glial cell lines, candoxin (CDX) induced cell death in a concentration (EC(50) approximately 1muM) and time dependent manner. Results of TUNEL-histochemistry further confirm CDX-induced brain (hippocampus, frontal cortex, and temporal regions) damage when administered intracerebroventricularly (i.c.v) in adult mice. In this study, we explored differential gene expression profiles following exposure of human glial (Hs 683) cell lines to CDX at various time intervals using Affymetrix-GeneChips. By means of MAS and GeneSpring analyses, 105 genes whose expression was significantly (P<0.01) altered by at least 3-fold were selected. Results of the genome analysis reveal that the potential role of CDX at molecular level involves ...
The authors have investigated insulin receptor phosphorylation in differentiated cultured BC3H-1 myocytes. As for other insulin-responsive cell systems in partially purified wheat germ agglutinin receptor preparations, insulin stimulates the phosphorylation of its own receptor (95K ..beta..-subunits) in a dose dependent manner (0-400 nM), as identified by immunoprecipitation with antiinsulin receptor antibodies and SDS-PAGE. In the same preparations they show that 12-0-tetradecanyl phorbol acetate (TPA), which in many respect ..beta..-subunits in the same dose dependent manner (0-5 ..mu..M). In addition, antiinsulin receptor antibodies (B-10) also induced phosphorylation of mimics insulin action, also induced phosphorylation of the insulin receptor and HPLC tryptic maps of the /sup 32/P-labeled ..beta..-subunit were identical to those for insulin-induced receptor phosphorylation. However, while insulin and TPA are potent stimulators of glucose ...
Magnetic resonance imaging (MRI) in stroke makes it possible to visualize the initial infarct in cases of acute cerebral ischemia. Perfusion MRI serves to determine which tissues are additionally at risk of infarction due to persistent hypoperfusion. MRI also allows those examiners with limited experience to reliably confirm an infarct. The most important differential diagnosis of cerebral ischemia, intracerebral hemorrhage, can likewise be recognized with certainty using MRI. Although diffusion and perfusion MRI only demonstrate the pathophysiology of cerebral ischemia approximately, the method is suited for identifying those patients who would profit from reperfusion therapy. Whether MRI is also appropriate as an aid to reaching a prognosis on the risk of secondary hemorrhage has not yet been resolved. (orig.) [German] Die Schlaganfall-MRT ermoeglicht es, bei akuter zerebraler Ischaemie den bereits initial entstandenen Infarkt darzustellen. ...
Energy and angular double differential cross-section data of fragments by tens of MeV neutron or proton are important to evaluate dosimetry and radiation effect in devices or instruments, since fragments cause a large local ionization. Up to now, experimental data of the fragment production are very scarce due to experimental difficulties of fragment detection. A bragg curve spectrometer (BCS) for fragment measurement is a gridded-ionization chamber that identify fragments on the basis of the difference of Bragg peak value. The BCS was fabricated to adopt for fragment measurement in neutron-induced reactions and tested with a charged-particle beam and then applied to a neutron field successfully. The structure of BCS is a cylindrical gridded ionization chamber, and filled with a Ar + 10% CH{sub 4} gas at a pressure of 2.7 x 10{sup 4} Pa. To confirm the performance of BCS, the following tests were performed: 1) the saturation property by using ...
In vertebrates, the positioning of the internal organs relative to the midline is asymmetric and evolutionarily conserved. A number of molecules have been shown to play critical roles in left-right patterning. Using representational difference analysis to identify genes that are differentially expressed on the left and right sides of the chick embryo, we cloned chick Claudin-1, an integral component of epithelial tight junctions. Here, we demonstrate that retroviral overexpression of Claudin-1, but not Claudin-3, on the right side of the chick embryo between HH stages 4 and 7 randomizes the direction of heart looping. This effect was not observed when Claudin-1 was overexpressed on the left side of the embryo. A small, but reproducible, induction of Nodal expression in the perinodal region on the right side of the embryo was noted in embryos that were injected with Claudin-1 retroviral particles on their right sides. However, no changes in ...
Temperature and concentration profiles of CO in a laminar, axisymmetric, premixed methane-air Bunsen flame are measured using line-of-sight diode laser absorption spectroscopy and computer tomographic (CT) reconstruction. Absorption spectra for P(20) (v=2<-1) and P(27) (v=1<-0) vibrotational transitions of CO were measured at 21 evenly spaced positions over a 1.33 cm span for a 1.3 cm radius flame. CT reconstruction algorithm was based on Fourier convolution. The tomographically reconstructed normalized transmission profiles derived from absorption spectra, in conjunction with a quantum mechanical model for vibrotational behavior of CO, yielded both temperature and concentration profiles. The Bunsen flame had 3 distinct zones: an inner rich-premixed flame zone, an outer non-premixed flame zone and an unburnt core region. The reconstructed temperature profile showed that the core region temperature was close to ambient ...
... In a first-of-its-kind operation, Lisnave recently converted Latvian Shipping Company's 20,000 dwt products tanker Dzintari into a full Class 3 ...
Plate-boundary earthquakes have occurred repeatedly in the past several thousand years at the Cascadia subduction zone, where they are widely recorded ... ...
A rapid and cost-effective assessment was required to provide advice to management on the connectivity between juvenile and adult life cycle stages of Baldchin Groper Choerodon rubescens, a labrid endemic to the west coast of Australia, which has high social value, but relatively low commercial fishery importance. To minimise costs we used laser ablation ICP-MS to analyse levels of a small suite of elements (Ca, Mg, Mn, Cu, Zn, Sr, Rb, Ba and Pb) at the margin (adult phase) and core (juvenile phase) of the same otoliths of adult C. rubescens, collected at ten locations in five management zones. The elemental composition of both otolith margins and cores differed significantly among management zones and in some cases among locations within zones. Similarity of the pattern of among-zone elem...
Equilibrium and energy equations have been developed in describing the solid-fluid transition zone during the melting and solidification of the binary alloys. Due to the existence of the transition region exhibited both solid and fluid phases at the same material point from continuum point of view, mixture theory was utilized to analyze the region. Unlike the Stefan problem, the latent heat due to the phase change appears as a source term in the heat equation. The molten fluid is treated as a thermoviscous and incompressible fluid, whereas the solid is thermoviscoplastic described by the Bodner-Partom/Walker type of constitutive equations. Thermal mechanical behaviors of the solid and the fluid phases are determined separately because of insignificant mechanical interactions between them. Volume fractions of the phases are obtained according to the equilibrium phase diagram. The simulation process of the transition zone and the welding process ...
Satellite Observations of the Southeast Pacific Intertropical Convergence Zone During 1993-1998, Halpern, D.; Hung, C.-W., Journal of Geophysical Research ? ...
Morphological, Electrophysiological and Behavioral Investigations of the Nervous Tissue Developed from the Embryonic Matrix Zone Cells of the Dorsolateral Walls of Lateral Ventricles, Implanted into the Lesioned Regions of the Adult Rat's Brain
The feasibility of continuous production of gallium arsenide ribbon single crystals, by passage of a molten zone through boron-oxide encapsulated GaAs feedstock, is being investigated. Polycrystalline GaAs ribbons have been grown in graphite boats by passage of a wide zone through B2O3-encapsulated feed-stock, confined by a quartz cover plate. Failure to remove the encapsulant above its glass transition temperature, however, resulted in cracking of the ribbons on cooling to room temperature. In order to study the crucial zone melting step in isolation from the encapsulation steps of the continuous process, a constrained-zone melting apparatus has been constructed in which the boron oxide serves only as a sealant to suppress arsenic vaporization. Large grained polycrystalline samples have been produced with this apparatus.
Rapid administration of stable iodine is essential for the saturation and subsequent protection of the thyroid gland against the potential harm caused by radioiodines. This paper proposes the Dutch risk analysis that uses an atmospheric dispersion model to calculate the size of the zones around nuclear power plants where radiological thyroid doses for children might be sufficiently high to warrant iodine administration. Dose calculations for possible releases from the nuclear power plants of Borssele (The Netherlands), Doel (Belgium) and Emsland (Germany) are based on two scenarios in combination with a 1-y set of authentic, high-resolution meteorological data. The dimensions of the circular zones were defined for each nuclear power plant. In these zones, with a radius up to 50 km, distribution of stable iodine tablets is advised. PMID:20332130
Rapid administration of stable iodine is essential for the saturation and subsequent protection of the thyroid gland against the potential harm caused by radioiodines. This paper proposes the Dutch risk analysis that uses an atmospheric dispersion model to calculate the size of the zones around nuclear power plants where radiological thyroid doses for children might be sufficiently high to warrant iodine administration. Dose calculations for possible releases from the nuclear power plants of Borssele (The Netherlands), Doel (Belgium) and Emsland (Germany) are based on two scenarios in combination with a 1-y set of authentic, high-resolution meteorological data. The dimensions of the circular zones were defined for each nuclear power plant. In these zones, with a radius up to 50 km, distrib...
Mexico is located in a transition zone between the Nearctic and Neotropical biogeographical regions and contains a rich and unique biodiversity. A total of 496 Bacillus thuringiensis...Full Text Available
Soil gas, soil, and water were assessed for organic and inorganic constituents at the former 19th Street landfill at Fort Gordon, Georgia, from February to September 2010. Passive soil-gas samplers were analyzed to evaluate organic constituents in the hyporheic zone and flood plain of a creek and soil gas within the estimated boundaries of the former landfill. Soil and water samples were analyzed to evaluate inorganic constituents in soil samples, and organic and inorganic constituents in the surface water of a creek adjacent to the landfill, respectively. This assessment was conducted to provide environmental constituent data to Fort Gordon pursuant to requirements of the Resource Conservation and Recovery Act Part B Hazardous Waste Permit process. The passive soil-gas samplers deployed in the water-saturated hyporheic zone and flood plain of the creek adjacent to the former landfill indicated the presence of total petroleum hydrocarbon (TPH) ...
Wnt signaling negatively regulates adipocyte differentiation, and ectopic expression of Wnt-1 in 3T3-L1 cells induces several downstream molecules of Wnt signaling, including Wnt-1 inducible signaling pathway protein (WISP)-2. In this study, we examined the role of WISP-2 in the process of adipocyte differentiation using an in vitro cell culture system. In the differentiation of 3T3-L1 cells, WISP-2 expression was observed in growing cells and declined thereafter. In the mitotic clonal expansion phase of adipocyte differentiation, WISP-2 expression was transiently down-regulated concurrently with up-regulation of CCAAT/enhancer-binding protein d expression. Treatment of 3T3-L1 cells in the differentiation medium with lithium, an activator of Wnt signaling, inhibited the differentiation pro...
This paper makes a case for "good politics for good education", with special reference to Nigeria. It surveys the impact of good and bad politics on the attainment of Meaningful Access to education with special focus on Nigeria's Universal Basic Education (UBE) programme. Good politics is to be likened to what the French call "la politique au sense noble du terme" (politics in the noble sense of the term--or statesmanship) while bad politics is to be likened to a "politique politicienne" (mere divisive politicking, or politics in its raw form). Politics in its raw form is concerned with seeking power for self-aggrandisement while politics in its noble form is concerned with seeking power for public good. In situations where good politics prevails, educational policies, programmes and delivery processes tend to produce the desirable outcome of "children passing through school and the school also passing through them". By combining the seven exclusion zones used ...
In early 2004, the U.S. Department of Energy (DOE) Richland and Fluor Hanford requested technical assistance from the DOE Headquarters EM-23 Technical Assistance Program to provide a team of technical experts to develop recommendations for mending the In Situ Redox Manipulation (ISRM) Barrier in the 100-D Area of the Hanford Site in Washington State. To accommodate this request, EM-23 provided support to convene a group of technical experts from industry, a national laboratory, and a DOE site to participate in a 2 1/2-day workshop with the objective of identifying and recommending options to enhance the performance of the 100-D Area reactive barrier and of a planned extension to the northeast. This report provides written documentation of the team's findings and recommendations. In 1995, a plume of dissolved hexavalent chromium [Cr(VI)], which resulted from operation of the D/DR Reactors at the Hanford site, was discovered along the Columbia River ...
The authors propose using synthetic aperture radar(SAR) for wind energy mapping of coastal zones. The SAR equipment is located on the European Space Agency ERS-1 and 2 and the RADARSAT satellites. Examples of wind energy maps and evaluations of their applications are given for the Norwegian west coast.
Our work is towards mechanistically understanding interactions of unsaturated bacterial biofilms and their extracellular polymeric substances (EPS) with actinide metals and metal surrogates under vadose zone conditions. Because metal contaminants in the vadose zone co-occur with organic pollutants, some of our work has included experiments with organic pollutants.
A slurry intake device is proposed which contains an inlet sleeve, housing with grating installed with the discharge end in the zone of the slurry outlet, and hinged deflector. In order to conserve the clay mud, it is equipped with a tie rod and two-arm lever which is kinematically linked to the deflector and the grating. It is installed by hinges in relation to the housing and the latter is attached by hinges to the inlet sleeve. The deflector is arranged in the zone of slurry outlet. The device is distinguished by the fact that the deflector is equipped with a cantilever on which a fixable weight is attached.
Numerical simulations are used to predict the migration of radionuclides from the disposal units at Material Disposal Area G through the vadose zone and into the main aquifer in support of a radiological performance assessment and composite analysis for the site. The calculations are performed with the finite element code, FEHM. The transport of nuclides through the vadose zone is computed using a three-dimensional model that describes the complex mesa top geology of the site. The model incorporates the positions and inventories of thirty-four disposal pits and four shaft fields located at Area G as well as those of proposed future pits and shafts. Only three nuclides, C-14, Tc-99, and I-129, proved to be of concern for the groundwater pathway over a 10,000-year period. The spatial and temporal flux of these three nuclides from the vadose zone is applied as a source term for the three-dimensional saturated ...
The coal bed methane (CBM) potential of five coal zones (the Kootenay, Gething, Gates, Brazeau, and Coalspur) in the Alberta foothills and mountains is re-evaluated. For evaluation, the coal zones are divided into shallow (200 to 2500 m depth) and deep (over 2500 m depth). The total gas content is estimated. Recommendations on how to obtain more reliable resource data and about producibility are included. 41 refs., 12 figs., 3 tabs., 2 apps.
Boiling phenomenon is responsible for impurities concentration in the liquid phase and then can involve chemically aggressive conditions. This paper presents the methodology developed by NOVATOME to know the water quality conditions in the boiling zone and under deposits, in order to improve corrosion tests and materials reliability and safety. Calculations show that concentration of chloride and sodium hydroxide for example can reach significant levels which may lead to corrosion risks. (author).
Peculiarities of design of the PGV-1000 horizontal steam generator affecting soluble impurity distribution in its water volume are considered in brief. The results of estimating sodium distribution in different zones of the steam generator are presented. The conclusion is made on the necessity of arrangement of representative measurements of sodium and chloride content in water volume of the steam generator, particularly, in the hot bottom zone for optimization of blow-through flowsheet and its regulations.
A new dual focal point electro-optic lens that is switchable to focusing and unfocusing is proposed and successfully demonstrated. This electro-optic lens is constructed by coating transparent fine electrodes in the Fresnel-zone plate onto a PLZT ceramic plate. Its focal length changes from 1.25 m to infinity binary at 515 nm with the external voltage of 210 V. PMID:20725208
Contents include: introduction; river systems; physical processes; chemical processes; estuaries and coastal zone; introduction; physical processes; chemical processes; the role of sediments; introduction; the anoxic layer; major-element chemistry; minor-element chemistry; the oxic-anoxic interface; assessment; introduction; analysis of sediments; modelling.
Resistive analogous meters for spatial and time characteristics in ocean agitation are most often used in practical oceanography in coastal zones but are based on bridge circuits determined to have shortcomings in their linearity range. This shortcoming is eliminated in the circuit of an instrument developed in an oceanographic laboratory (IMIO, Vana). Principle and block circuits are indicated, and static calibration curves are presented as are the correlative functions in the frequency spectrums obtained with the help of sea agitation recorded at a fixed point and at a depth of 6 meters.
Transport and deposition of atmospheric lead over the coastal zone of Northern Germany are investigated. It is shown that marked differences in the impact of the ecologically valuable wadden sea areas can occur between summer and winter time. Due to the formation of sea breeze systems in summer the coastal zone is likely to be less stressed than in winter when the pollutant is confined to a shallow layer above ground. (orig.) 10 refs.
Previous models of fault-propagation folding used kink-band geometries to approximate folding in front of propagating thrusts. However, kink-band kinematics cannot replicate the curved fold surfaces and complex strain patterns innatural and experimental fault-propagation folds, which also occur in front of steeper reverse and normal faults. Fault-propagation fold hinges tighten and converge downward, forming a triangular zone of penetrative deformation focused on the tip of the propagating fault. The downward convergence of deformation in fault-propagation folds can be modeled as triangular shear zones. Trishear, here defined as distributed, strain-compatible shear in a triangular (in profile) shear zone, provides an alternate kinematic model for fault-propagation folds. Trishear is analogous to simple shear in a tabular shear zone except that area balance in a triangular shear zone ...
The relationship between the QRS transition zone of the standard 12-lead ECG and interventricular septum was studied. The position and the angle to the horizontal line of the interventricular septum were evaluated with computed tomography (CT) and compared to the QRS transition zone. The subjects were 36 patients with no cardiovascular diseases. The patients were divided into 3 groups according to the position of QRS transition zone: V{sub 1}-V{sub 2} (8 cases), V{sub 3}-V{sub 4} (21 cases), and V{sub 5}-V{sub 6} (7 cases). The interventricular septum on CT was directed to the anterior chest wall between V{sub 3} and V{sub 4} in all 3 groups. The mean value of the interventricular septal angle did not differ from group to group, 52.1deg for V{sub 1}-V{sub 2} group, 49.8deg for V{sub 3}-V{sub 4} group, and 48.2deg for V{sub 5}-V{sub 6}. It was concluded that the direction of the interventricular septum was not one of the ...
Technique, allowing to investigate straggling zone (full braking) from high-energy charged particles in detail, is described. Experimental results on investigation of efective structure, created in polycrystalline molybdenum (99.97%) within 29 MeV alpha-particles straggling zone for fluences from 3.8x10"1"9 up to 3.7x10"2"1 #alpha#/m"2 by methods of microhardness (H_#mu#, X-ray structural analysis (#DELTA#a/a) and transparent electron microscopy (TEM), are presented. It is determined, that for doses from 3.8x10"2"0 #alpha#/m"2 and higher, at #approx#6 MeV energy, molybdenum ''softening'' is observed, H_#mu# curve within straggling zone is well described by alloyage calculated profile. #DELTA#a/a measurements within straggling zone are well described by damage profile. TEM-investigations have shown the developed defective structure even within molybdenum ''softening'' range.
On June 19, 1998, after the first annual outage, Wolsung Unit 2 was shutdown at a controlled rate due to the continuous instability of Liquid Zone Control level. Investigation revealed that the Liquid Zone Control level instability was caused by water condensed inside the helium lines, generated from the moistened helium flow, especially, inside the helium balance header feed and bleed valve lines. It was found that improper installation of the diaphragm type isolation valves and the drain valve tap could easily contain the water inside the lines and be destined to form water traps causing the balance header pressure oscillation. After the lines were dried, Liquid Zone Control level instability was almost vanished, and approached the allowable equilibrium state. As the reactor power was increased, however, the zone level instability increased again. In order to compensate for the excessive, the Bulk ...
We study the emission zone in a single-layer polymer light-emitting diode. The emission zone is found by studying the angular distribution of the electroluminescence. The emission is modeled by accounting for optical interference. We account for birefringence of the anode layer in our model. The active polymer was, however, found to be isotropic. The anode consists of a single-layer of the conducting polymer complex poly(3,4-ethylenedioxythiophene) and poly(styrene sulfonate) (PEDOT-PSS), with enhanced conductivity. As a cathode we use plain aluminum. By using only PEDOT-PSS we avoid having a thin metal layer or indium-tin-oxide as the anode in the path of the escaping light. The active material is a substituted polythiophene with excellent film forming properties. A comparison between the experimental and calculated angular distribution of light emission from a single-layered polymer light-emitting diode was shown to be in good agreement for ...
During the early years of the INEL, the USGS conducted extensive studies (sitewide drilling program) of the geology and hydrology of the area collecting varied data over the years. The unsaturated zone has not received much attention until recently. The studies that have been done are a result of problems or concerns arising from liquid radioactive waste disposal. The TRA facility has the most information published about its waste disposal activities. The ICPP has less data about the unsaturated zone due to the fact that most waste water disposal has been to a well. Little is known about the effect of waste water disposal at the NRF on the unsaturated zone. Essentially no information was found about waste disposal activities at other facilities, primarily because there does not appear to be any reported problems associated with waste water disposal at these locations. The RWMC has received much attention in the last few ...
During the early years of the INEL, the USGS conducted extensive studies (sitewide drilling program) of the geology and hydrology of the area collecting varied data over the years. The unsaturated zone has not received much attention until recently. The studies that have been done are a result of problems or concerns arising from liquid radioactive waste disposal. The TRA facility has the most information published about its waste disposal activities. The ICPP has less data about the unsaturated zone due to the fact that most waste water disposal has been to a well. Little is known about the effect of waste water disposal at the NRF on the unsaturated zone. Essentially no information was found about waste disposal activities at other facilities, primarily because there does not appear to be any reported problems associated with waste water disposal at these locations. The RWMC has received much attention in the last few ...
Treatment of cultures of 3T3-L1 cells with methylisobutyl-xanthine and dexamethasone has been shown to result in accumulation of lipid and conversion to the morphology of adipocytes in more than 90% of the cells. The status of the stimulatory (Gs), inhibitory (Gi) and Go-proteins during the course of 3T3-L1 differentiation was examined. The amount of alpha subunit of Gs (#alpha#Gs), assayed by radiolabeling in the presence of cholera toxin and ["3"2P]NAD"+, increased upon differentiation as previously described by others. The amounts of #alpha#Gi and #alpha#Go assayed by radiolabeling in the presence of pertussis toxin and ["3"2P]NAD"+ increased 3-fold upon differentiation. Immunoblots of cell membranes subjected to gel electrophoresis in sodium dodecyl sulfate were probed with two rabbit antisera raised against bovine brain #alpha#Go and with one raised against the#beta#-subunit of the bovine rod-outer-segment G-protein, ...
Transforming growth factor beta (TGF-@b) has a crucial role in the differentiation of ectodermal cells to neural or epidermal precursors. TGF-@b and bone morphogenetic protein molecules (BMPs) are involved in many developmental processes, including cell proliferation and differentiation, apoptosis, mitotic arrest and intercellular interactions during morphogenesis. Additionally, the failure of central thymic tolerance mechanisms, leading to T cells with a skewed autoreactive response, is being described as a contributor in inflammatory processes in autoimmune diseases such as multiple sclerosis. Since TGF-@b and BMP proteins are crucial for the development of the neural system and the thymus, as well as for the differentiation of T cells, it is essential to further investigate their role i...
The paper is concerned with the simulation of practical testing situations which are too difficult and/or expensive to replicate in a laboratory environment. Numerical experiments are described which simulate the differential eddy current probe response to the build-up and chemical flushing of magnetite in the crevice gap of a PWR steam generator unit. The simulation results agree well with the only experimental data available to the authors and lead to the conclusion that conventional differential eddy current probes should be capable of characterizing crevice gap conditions with respect to the presence of magnetite. (author).
The total and differential atomic pair-correlation functions of an icosahedral (quasicrystalline) solid were determined for the first time, directly by the differential anomalous-x-ray-scattering technique using synchrotron radiation. The observed atomic distances involving uranium atoms in icosahedral Pd/sub 58.8/U/sub 20.6/Si/sub 20.6/ suggest the presence of a quasicrystalline sublattice with vertex decoration. The pair distribution functions in the icosahedral and amorphous phases are similar up to the second-nearest neighbors, or up to 6 A-circle.
The total and differential atomic pair-correlation functions of an icosahedral (quasicrystalline) solid were determined for the first time, directly by the differential anomalous-x-ray-scattering technique using synchrotron radiation. The observed atomic distances involving uranium atoms in icosahedral Pd/sub 58.8/U/sub 20.6/Si/sub 20.6/ suggest the presence of a quasicrystalline sublattice with vertex decoration. The pair distribution functions in the icosahedral and amorphous phases are similar up to the second-nearest neighbors, or up to 6 A-circle.
A new simple multi-well plate-based assay to determine monocyte differentiation-inducing activity was developed. It is based on the increase of macrophage adherence after the induction of monocyte differentiation. The assay was conducted using a human monocytic leukemia cell line, THP-1, treated with either 12-O-tetradecanoylphorbol 13-acetate or cytokines, such as tumor necrosis factor-alpha and interferon-gamma. This method is sensitive and easy to perform, especially in case of analyzing a large number of samples. PMID:17920620
A new simple multi-well plate-based assay to determine monocyte differentiation-inducing activity was developed. It is based on the increase of macrophage adherence after the induction of monocyte differentiation. The assay was conducted using a human monocytic leukemia cell line, THP-1, treated with either 12-O-tetradecanoylphorbol 13-acetate or cytokines, such as tumor necrosis factor-? and interferon-?. This method is sensitive and easy to perform, especially in case of analyzing a large number of samples.
Gamete development requires a coordinated soma-germ line interaction that ensures renewal and differentiation of germline and somatic stem cells. The physical contact between the germline and somatic...Full Text Available
The mammalian placenta consists of different trophoblast cell types that assist in the variety of functions required for the maintenance of pregnancy. In rodents, labyrinthine trophoblasts of the placenta are especially important, because they are capable of differentiating into fused labyrinthine cells, which form the feto-maternal exchange surface. Even though the molecular signals triggering labyrinthine trophoblast differentiation are poorly understood, transforming growth factor-b (TGF-b) has been shown to be present in the placental environment and alter trophoblast development. In this study, we investigated the effects of TGF-b on the differentiation of the labyrinthine trophoblast stem cell lines SM10 and HRP-1. RT-PCR analyses demonstrated that while the molecular expression of l...
Nuclear transfer technology can be applied to produce autologous differentiated cells for therapeutic purposes, a concept termed therapeutic cloning. Countless articles have been published on the ethics...Full Text Available
A diagnosis of dementia is devastating at any age but diagnosis in younger patients presents a particular challenge. The differential diagnosis is broad as late presentation of metabolic disease...Full Text Available
Background:Solid pseudopapillary tumor is a rare pancreatic neoplasm with uncertain to low malignant potential. This is an uncommon neoplasm with many pseudonyms, occurring...Full Text Available
Differentiation of the vertebrate communities almost coincides with the differentiation of ecosystems in vegetation at the type level, as judged by formalized classifications of various blocks of ecosystems of West Siberia by geobotanical map units, and it differs significantly from that in the underground component due to the greater effect of waterlogging on the latter. In invertebrate communities, significant differences are observed in the boreal-subboreal part, where waterlogging is more significant and greater similarity is found among middle and southern-taiga communities than among subtaiga-steppe ones. Over the groups of map units, the heterogeneity of the vertebrate communities differs from that in all the examined blocks of ecosystems in greater differentiation in the tundra zon...
Studies on the regulation of the enterocytic differentiation of the human colon cancer cell line HT-29, which is differentiated in the absence (Glc"-) but not in the presence of glucose (Glc"+), have recently shown that the post-translational processing of sucrase-isomaltase and particularly its glycosylation vary as a function of cell differentiation. Other studies indicate that in undifferentiated HT-29 Glc"+ cells there is an accumulation of UDP-N-acetylhexosamine, which is involved in the glycosylation process. The purpose of the present work is to investigate whether an overall alteration of protein glycosylation is associated with the inability of HT-29 cells to differentiate. At least three alterations are detected: (i) after a 10-min pulse, the incorporation of D-[2-"3H]mannose in undifferentiated cells is severely reduced, compared to differentiated cells. (ii) After a 24-h ...
Synthetic polymers and nanomaterials display selective phenotypic effects in cells and in the body that affect signal transduction mechanisms involved in inflammation, differentiation, proliferation,...Full Text Available
ObjectiveTo examine the extent to which the regional and neighborhood distribution of HIV in Tanzania is caused by the differential distribution of individual correlates...Full Text Available
... 2. Federal Employees Retirement System (FERS) ... . 17 ... a. Straight and differential pay b. Bcnefits: retirement, sick leave, health insurance ...
Recent molecular characterizations of Cryptosporidium parasites make it possible to differentiate the human-pathogenic Cryptosporidium parasites from those that do...Full Text Available
PASTICCINO (PAS) genes are required for coordinated cell division and differentiation during plant development. In loss-of-function pas mutants,...Full Text Available
The DN-tracking method is used to prove the existence of a closed trajectory in a quadratic system of ordinary differential equations in three dimensions.
Privacy-preserving machine learning algorithms are crucial for the increasingly common setting in which personal data, such as medical or financial records, are analyzed. We provide general...Full Text Available
TP63, a member of the TP53 gene family, is a nuclear marker of myoepithelial cells. Antibody against p63 is frequently used to aid in the diagnosis of prostate carcinoma, as well as in the identification of myoepithelial cells in other tissues including the breast. p63 is also a marker for squamous cell carcinoma. Recently, it was found that all p53 family members are involved in regulating the process of muscle differentiation through the retinoblastoma (RB) protein. Ablation of these p53 family functions blocks the differentiation program and promotes malignant transformation by enabling cooperating oncogenes to transform myoblasts. We therefore studied p63 expression in a number of neoplasms with myogenic differentiation. Immunohistochemical staining for p63 was performed on paraffin se...
Cells of the mononuclear phagocyte lineage have the capability to adhere to and fuse with each other and to differentiate into osteoclasts and giant cells. To investigate the macrophage adhesion/fusion...Full Text Available
CAAX proteins are widely involved in global cellular functions such as proliferation, differentiation, and carcinogenesis. As an important modulator of biological activity, signal transduction via protein...Full Text Available
aerodynamic force and moment values. Only the solid and the 25 percent porous dishes were tested for the static pressure values used primarily to determine ...
Fatty acids such as stearic acid (SA), palmitic acid (PA), myristic acid (MA), and lauric acid (LA) are promising phase change materials (PCMs) for latent heat thermal energy storage (LHTES) applications, but high cost is the most drawback which limits the utility area of them in thermal energy storage. The use of fatty acids as form-stable PCM will increase their feasibilities in practical LHTES applications due to reduced cost of the energy storage system. In this regard, a series of fatty acid/poly(methyl methacrylate) (PMMA) blends, SA/PMMA, PA/PMMA, MA/PMMA, and LA/PMMA were prepared as new kinds of form-stable PCMs by encapsulation of fatty acids into PMMA which acts as supporting material. The blends were prepared at different mass fractions of fatty acids (50, 60, 70, 80, and 90% w/w) to reach maximum encapsulation ratio. All blends were subjected to leakage test by heating the blends over the melting temperature of the PCM. The blends that do not allow leakage of melted PCM ...
SiC-AlN and SiC-SiAlON refractory composites were obtained by means of nitridation of the mixtures of silicon carbide (SiC) powder with a broad granulometric distribution and powders of aluminium (Al) and aluminium-silicon (Al-Si) mixtures. The mixtures of the composition Al-25% Si, Al-50% Si and Al-75% Si were previously prepared by means of 'mechanical alloying' technique. Thermodynamic analysis was accomplished in order to evaluate the viability of SiC-SiAlON and SiC-AlN refractories production by the chosen processing method, and the results confirmed viability of such. Investigation of nitridation of Al and Al-Si powder compacts in order to obtain the AlN and #beta#-SiAlON matrix phases of the composite was accomplished by means of differential thermal analysis (DTA) and thermogravimetric analysis (TG). The results of the thermal analysis show that nitridation of the Al-25% Si, Al-50% Si and Al-75% Si resulting in p-SiAlON formation occur at temperatures of ...
We present a technique for identifying the amino acids responsible for a loss of immunoreactivity in response to treating an antigen with a chemical modifier. This is of particular interest...Full Text Available
The features of present deposits that form in the vicinity of hot springs can provide clues to the parameters of paleowaters in places of past hydrothermal activity marked by remnant carbonate and/or siliceous sinter. We investigated a large carbonate body at the Garga hot spring developing in the Baikal zone of nitric hydrotherms in the Barguzin Rift Zone valley. The main focus was on the structure of the carbonate mound, as well as on the partitioning of radioactive elements between the cyanobacterial mat and the inorganic component of the body (the issue that has never been explored before). The cyanobacterial community of the Garga spring is an active biosorbent of 226Ra, 228Ra, 210Pb. The radionuclides accumulated by biosorption become preserved in minerals that form within the bacter...
The subscale Varestraint test has been used to determine the relative hot cracking susceptibility of the fusion zone in four commercial heats of alloy 800. Although all four heats were susceptible to cracking, one heat exhibited a significant increase in cracking relative to the other three. Optical metallography revealed that nearly all the cracking was localized along fusion zone grain boundaries. Microprobe analysis of the grain boundaries detected high concentrations of titanium, silicon, and niobium resulting from partitioning during solidification. The fusion zone hot cracking mechanism in alloy 800 involves the complex interaction of titanium, silicon, niobium, and carbon along the solidification boundaries. SEM and Auger analyses of the hot crack fracture surfaces revealed the presence of (Ti, Nb)-rich carbides, suggesting that these particles precipitate from the liquid which solidifies last on the fracture ...
Riparian zones of streams in northwestern Mississippi have been impacted by agriculture, channelization, channel incision, and gully erosion. Riparian gully formation has resulted in the fragmentation of remnant riparian zones within agricultural watersheds. One widely used conservation practice for controlling gully erosion is the installation of drop pipes. This practice involves placing earthen dams across eroding gullies and embedding a metal standpipe within the dam to convey water from the field to stream level. Installation of this structure halts gully erosion and incidentally replaces eroding gullies with riparian habitats. Previous research evaluating gully erosion control structures have not considered the ecological impacts of these conservation practices on amphibian and repti...
Competitive bidding for ancillary services (A/S), in addition to bidding for energy, is increasingly recognized as an important part of electricity markets. In this paper, an LP-based approach is presented for solving the multi-product (i.e. energy and A/S products), multi-zone/area physical market dispatch problem. The approach can explicitly represent various constraints, such as reserve requirement constraints, network security limits, and sharing of constrained resource capacity (e.g. maximum unit generation) between energy and reserve. The joint dispatch method, which dispatches energy and reserve market concurrently, is extended to allow inter-zonal reserve trading in multi-zone competitive pool. Numerical examples are included to demonstrate the salient characteristics of the joint dispatch solution.
Testimony at an April 30, 1980 hearing addressed whether to reauthorize or amend the Coastal Zone Management Act of 1978, specifically section 306, to further implement state programs and institutionalize state management of coastal zones. The text of the reauthorization bill (S. 2622) is followed by the statements of eleven witnesses and additional articles, letters, and statements submitted for the record. Witnesses are present for the fishing and oil industries, state and national governments, and public interest groups. Among the points brought out in testimony were that uniform standards are unwise - given the variety of coastal regions; and that there is a need to balance protection and development policies. (DCK)
The Jaduguda U (?Cu?Fe) deposit in the Singhbhum shear zone has been the most productive uranium deposit in India. Pyrite occurs as disseminated grains or in sulphide stringers and veins in the ore zone. Veins, both concordant and discordant to the pervasive foliation, are mineralogically either simple comprising pyrite ? chalcopyrite or complex comprising pyrite + chalcopyrite + pentlandite + millerite. Nickel-sulphide minerals, though fairly common in concordant veins, are very rare in the discordant veins. Pyrite in Ni-sulphide association is commonly replaced by pentlandite at the grain boundary or along micro-cracks. Based on concentrations of Co and Ni, pyrite is classified as: type-A ? high Co (up to 30800?ppm), no/low Ni; type-B ? moderate Co (up to 16500?ppm) and moderate to high ...
Abstract Introduction.- Infection is the worst complication seen with inflatable penile prosthesis (IPP). Both the American Medical Systems (AMS) and Coloplast IPP have infection retardant coatings. AMS is coated at the factory with rifampicin and minocycline (InhibiZone). The Coloplast IPP has a hydrophilic coating covalently bonded to its components that will absorb any aqueous solution before implantation and provides increased surface lubricity to decrease bacterial adherence. Aim.- We tested several antibiotic dips comparing zones of inhibition (ZOI) against five commonly infecting bacteria with coated Coloplast implants. Results were compared with those ZOI created with strips of an AMS IPP precoated with InhibiZone. Methods.- Pieces of sterile Coloplast Titan IPP were dipped in (i) ...
The most relevant aspects of research and service experience with environmentally-assisted cracking (EAC) of carbon (C) and low-alloy steels (LAS) in high-temperature (HT) water are reviewed, with special emphasis on the primary pressure boundary components of boiling water reactors (BWRs). The main factors controlling the susceptibility to EAC under light water reactor (LWR) conditions are discussed with respect to crack initiation and crack growth. The adequacy and conservatism of the current BWRVIP-60 stress corrosion cracking (SCC) disposition lines (DLs), ASME III fatigue design curves, and ASME XI reference fatigue crack growth curves, as well as of the GE EAC crack growth model are evaluated in the context of recent research results. The operating experience is summarized and compared to the experimental/mechanistic background knowledge. Finally, open questions and possible topics for further research are identified. Laboratory investigations revealed ...
This study focuses the granitoids of center-southern portion of Guyana Shield, southeastern Roraima, Brazil. The region is characterized by two tectonic-stratigraphic domains, named as Central Guyana (GCD) and Uatuma-Anaua (UAD) and located probably in the limits of geochronological provinces (e.g. Ventuari-Tapajos or Tapajos-Parima, Central Amazonian and Maroni-Itacaiunas or Transamazon). The aim this doctoral thesis is to provide new petrological and lithostratigraphic constraints on the granitoid rocks and contribute to a better understanding of the origin and geo dynamic evolution of Guyana Shield. The GCD is only locally studied near to the UAD boundary, and new geological data and two single zircon Pb-evaporation ages in mylonitic biotite granodiorite (1.89 Ga) and foliated hastingsite-biotite granite (1.72 Ga) are presented. These ages of the protholiths contrast with the lithostratigraphic picture in the other areas of Cd (1.96-1.93 Ga). Regional mapping, petrography, ...
It has been acknowledged that river morphology and hydrology have been intensively altered due to the anthropic demands in floodplain land use and management, flood protection, promotion of navigability or energy production. Rivers were transformed in water highways, having lost contact with their surrounding floodplain as well as the plethora of ecological processes and occupants once thriving in these ecotonal zones. The identification of this emerging threat of morphological and hydrological alteration on ecological integrity adds further complexity in the exploitation of hydrosystem resources. These resources are heavily coveted and guarded by different lobbies each having strategic views on future project development. Stakeholders may want to promote hydro-electricity, ecologists a natural reserve, communes may wish to have an increased flood protection and leisure promoters a nautical center. As a result, the proposition of a river development project is ...
The present investigation was aimed to assess the usefulness of biliary agents scintigraphy in the diagnosis of hepatocellular carcinoma (HCC) and to ascertain the relationship between the uptake of these agents and the degree of HCC differentiation. Forty-four patients with this hepatic cancer were included in the study. Liver scans were performed 20 min and 3 hr after the administration of 99mTc diisopropyliminodiacetic acid (DISIDA). DISIDA scintigraphy could not be assessed in six cases. In 16 (42%) out of the remaining 38 patients, the tumor exhibited equal or greater radioactivity uptake than the surrounding liver. In six out of these 16 patients, tumor uptake was apparent in the early and delayed hepatic scans, while in the other ten subjects radioactivity uptake by the HCC could only be detected in the 3-hr delayed scans. In the remaining 22 patients, HCC appeared as a cold area. Tumor location by this technique did not differ from that observed by ...
The status of neutron activation cross sections for some threshold reactions important for reactor materials dosimetry is reviewed. An attempt is made to understand and explain discrepancies between integral and differential data, using recent available experimental results. The importance of standard and benchmark neutron fields for testing differential data for reactor dosimetry is emphasized and the Interlaboratory Reaction Rate (ILRR) program, as well as a similar program pursued by the IAEA, are briefly described.
Here the authors try to dissolve some commonly held misconceptions about the operation of eddy current probes used for inspecting heat exchanger tubes. With the help of computer model results, the authors demonstrate that, for optimized operation, absolute/differential probes should be operated with coil current flowing in phase with another. This month's feature should be of interest to researchers as well as for NDT field personnel.
A cDNA library was constructed from HL60 human promyelocyte poly(A)+ RNA harvested 3 h after induction of macrophage differentiation with 12-O-tetradecanoyl phorbol-13-acetate in the presence of cycloheximide....Full Text Available
A new external-PIXE system utilizing a differential pumping technique, which can completely protect the accelerator and vacuum pumps when the exit foil breaks down, has been developed. Applications to analyses of liquid and heavily-outgassing samples were successfully achieved. Also, experiments for evaluating the efficiency of the system were performed and results will be presented. (author)
Growth differentiation factor-9 (GDF-9), an oocyte-secreted member of the transforming growth factor β superfamily, progesterone receptor, cyclooxygenase 2 (Cox2; Ptgs2), and the EP2 prostaglandin...Full Text Available
Various physics applications involve the computation of the standard hypergeometric function {sub 2}F{sub 1} and its derivatives. Because it is not an intrinsic in the common programming languages, automatic differentiation tools will either differentiate through the code that computes {sub 2}F{sub 1} if that code is available or require the user to provide a hand-written derivative code. We present options for the derivative computation in the context of an ionization problem and compare the approach implemented in the Diamant library to standard methods.
BackgroundThe differentiation of CD8+ T lymphocytes following priming of naïve cells is central in the establishment of the adaptive immune response. Yet, the...Full Text Available
The application of differential optical absorption (DOA) techniques for the in-situ determination of the chemical composition of coal gasification process streams is investigated. Absorption spectra of relevant molecular species and the temperature and pressure effects on DOA-determined spectral characteristics of these species will be determined and cataloged. A system will be configured, assembled, and tested.
The radiologic appearance of inflammatory and tumorous lesions in the iliac bone is characterized by destructive alterations and consolidations simultaneously. This pattern is nonspecific. The value of plain films of this area is compromised by the anatomy of the iliac bone and by overlying structures. Therefore tomography, computer tomography and bone scans are necessary. Difficulties in differentiation between benign and malignant lesions are discussed and case reports are given. The importance of histologic examination is stressed.
A theoretical model is proposed for analyzing elastic scattering of 100-150 MeV #alpha#-particles on intermediate mass nuclei. It is shown that, within the scope of this model accounting for inhomogeneous target-nucleus density, an anomalous growth of differential cross section of elastic scattering in the region of average angles can be explained.
A physical explanation is given for the positive differential voltage-current characteristic seen at low current in weakly ionized, low-pressure positive column discharges in argon/mercury gas mixtures. {copyright} {ital 1996 The American Physical Society.}
This paper mainly considers the asymptotic stability of interval neutral delay-differential systems, which corrects a technical error in the proof given in [Applied Math. Letters, 16(2003) 1063-1068] by a linear fractional transformation of an interconnection matrix with structured real parametric uncertainties. In addition, a new condition, in terms of the structured singular value, is provided to ensure the stability of the interval system. Finally, an example is given to demonstrate the validity of our criteria.
Tea catechin is one of the compounds that are closely related to obesity and insulin sensitivity. In order to determine the effect of catechin on adipocyte differentiation, we treated 3T3-L1 preadipocytes...Full Text Available
"9"9"mTc-tetrofosmin has been used in the imaging of cancers of diverse origin. In this report the use of it in the family of round cell tumors, mainly Ewing's sarcoma and peripheral neuroectodermal tumor (PNET), where differentiation between the two is not always simple on the basis of histopathological features alone is discussed
Underground injection, compared to other waste disposal methods, is considered to have the advantages of isolating wastes in a confined brine aquifer well below the horizon of human activity and underground sources of drinking water (USDWs). While most of injected wastes move laterally in the injection zone, posing a long-term concern to the human health and environment, a small amount can migrate upward to the upper aquifers, causing a greater threat to the quality of USDWs. Both the dual porosity and the single porosity models were used to investigate the migration of injected wastes through these hydrologic conduits. The results indicate that regional upward migration through an extensive confining formation is a slow process. Nevertheless, injected wastes can move upward rapidly through microannuli and channels in the cement sheath and spread over a distance in the upper aquifer. The wastes can also migrate fast through fractures in the disturbed ...
We explored ways of doing spatial search within a relational database: (1) hierarchical triangular mesh (a tessellation of the sphere), (2) a zoned bucketing system, and (3) representing areas as disjunctive-normal form constraints. Each of these approaches has merits. They all allow efficient point-in-region queries. A relational representation for regions allows Boolean operations among them and allows quick tests for point-in-region, regions-containing-point, and region-overlap. The speed of these algorithms is much improved by a zone and multi-scale zone-pyramid scheme. The approach has the virtue that the zone mechanism works well on B-Trees native to all SQL systems and integrates naturally with current query optimizers - rather than requiring a new spatial access method and concomitant query optimizer extensions. Over the last 5 years, we have used these techniques extensively in our work on ...
Using the linearized augmented-plane-wave (LAPW) -calculated electron and positron charge densities for YBa_2Cu_3O_7, the Brillouin-zone-reduced electron-positron momentum density is computed and the zone-reduced two-dimensional angular correlation of annihilation radiation (2D ACAR) spectrum is produced. The calculations show that the relative weights of the Fermi-surface discontinuities are substantially altered due to the positron preferentially sampling the Cu-O chain region. In addition, the reduced 2D ACAR spectrum contains large k-dependent wave-function effects. The theoretical zone-reduced 2D ACAR spectrum is compared to the several existing experimental spectra. It is concluded that, at present, positron-annihilation experiments do not provide consistent and clear evidence for the existence and shapes of Fermi surfaces in YBa_2Cu_3O_7.
BackgroundWhile the gene flow in some organisms is strongly affected by physical barriers and geographical distance, other highly mobile species are able to overcome such constraints....Full Text Available
The receptive field of a neuron reflects its function. For example, for parallel fiber (PF) inputs in C3 zone the cerebellar cortex, the excitatory and inhibitory receptive fields of a Purkinje cell...Full Text Available
The following subjects are dealt with: physics of indoor air flow, flow in individual rooms, exchange of air and pollution between individual building zones and with the outside world, thermal coupling with the building shell, thermal comfort and air quality, evaluation of the ventilation. figs., tabs., refs.
Current military conflicts in Iraq and Afghanistan have produced a significant number of complex injury patterns. Multiple extremity trauma and wide zones of injury mandate a flexible approach to these...Full Text Available
Treatment of Japanese pines (P. densiflora and P. thunbergii) with paraquat induced a zone of lightwood. Determinations of turpentine and ether extractives contents in lightwoods showed high levels as compared with those in control woods. (Refs. 5).
...this pathway study the following two focus modules (in addition to the six core modules) and carry out a research investigation within this theme: Agricultural Production Systems Considers the type of farming systems that have evolved globally in relation to the prevailing agro-climatic zones, the influences of economic factors ...
Coded imaging techniques using thick, micro-Fresnel zone plates as coded apertures have been used to image x-ray emissions (2-20 keV) and 3.5 MeV Alpha particle emissions from laser driven micro-implosions. Image resolution in these experiments was 3-8 ..mu..m. Extension of this coded imaging capability to higher energy x-rays (approx. 100 keV) and more penetrating charged particles (e.g. approx. 15 MeV protons) requires the fabrication of very thick (50-200 ..mu..m), high aspect ratio (10:1), gold Fresnel zone plates with narrow linewidths (5-25 ..mu..m) for use as coded aperatures. A reactive ion etch technique in oxygen has been used to produce thick zone plate patterns in polymer films. The polymer patterns serve as electroplating molds for the subsequent fabrication of the free-standing gold zone plate structures.
Coded imaging techniques using thick, micro-Fresnel zone plates as coded apertures have been used to image x-ray emission (2--20 keV) and 3.5 MeV Alpha particle emissions from laser driven micro-implosions. Image resolution in these experiments was 3--8 ..mu..m. Extension of this coded imaging capability to higher energy x rays (approx.100 KeV) and more penetrating charged particles (e.g., approx.15 MeV protons) requires the fabrication of very thick (50--200 ..mu..m), high aspect ratio (10:1), gold Fresnel zone plates with narrow linewidths (5--25 ..mu..m) for use as coded apertures. A reactive ion etch technique in oxygen has been used to produce thick zone plate patterns in polymer films. The polymer patterns serve as electroplating molds for the subsequent fabrication of the free-standing gold zone plate structures.
A method is proposed for operating bed waters in an oil well by injecting silanes into the near-face zone. It is distinguished by the fact that in order to improve the effectiveness of insulation, the silanes used are silanes of general formula Si /SUB n/ H /SUB 2n-n/ .
Background and AimsSulfonylurea (SU) herbicides are used extensively in cereal–livestock farming zones as effective and cheap herbicides with useful levels of residual activity....Full Text Available
The effects of the plasma nitriding with the formation of compound nitride and diffusion zones and of the boronising with the different ion doses on hydrogen distribution and hydrogen induced deterioration of a surface layer were examined in the case of Armco iron. Electrochemical studies of hydrogen permeation rate, hydrogen vacuum extraction measurements, optical and scanning microscopy, X-ray diffraction and elastic recoil detection analysis (ERDA) were used. Accumulation of entering hydrogen within the various constituent zones of the modified layer inhibits the hydrogen transport into the metal and thus, decreases the mean hydrogen content in the deeper zones and in the core. Hydrogen accumulation within the compact nitride zone causes the expansion of the nitride lattice, nitride phase transformation and deterioration. The ion boronising enhances the hydrogen effects in the plasma nitrided layers. ...
Foreward: Preface; Introduction; The natural science of global climate change; Land and water use; Coastal zones and oceans; Energy and industry; Energy and social systems; Technological change; and Sponsoring organizations, International Advisory Board, and project participants.
Field campaigns were conducted in 1981 and 1982/83 on the Dutch coast near Egmond. Measurements were made of surface elevations, water velocities and sediment concentrations in 3 to 8 surf zone locations and 2 to 5 offshore locations simultaneously. A des...
A triangle zone, which commonly occurs along the external margin of a foreland thrust and fold belt with a buried thrust front, is underlain by a subhorizontal, blind, foreland-verging thrust that ends against a foreland-dipping, hinterland-verging thrust. These contemporaneous thrusts, active towards the end of orogenesis, enclose an intercutaneous wedge that moved towards the foreland. During orogenesis, a triangle zone evolves through periodic replacement of faults bounding the active wedge. Replacements occur in cycles during each of which a lower fault tends to be replaced by one in a lower stratigraphic horizon, an upper fault by one farther away from the foreland. Each cycle ends with the lower fault moving to a younger horizon where it joins a new, more external upper fault. Near Coalspur, the triangle zone exposes the remnants of several wedges involving Upper Cretaceous and Palaeocene molasse. Most of these wedges ...
Sulfur dioxide emissions from an iron ore sintering plant have severely damaged vegetation up to 16 km northeast of the source. Concentric zones of increasing vegetation loss have formed around the point of maximum ground level concentration of the gas. Species diversity, sulfur and heavy metal concentrations in vegetation and soil amount to SO/sub 2/ injury were measured along a transect through the injury zones. Surrounding a central denuded area were zones dominated respectively by tussock-forming hair grass (Deschampsia flexuosa); low-growing shrubs and trailers (Sambucus pubens, Polygonum cilinode); higher-growing shrubs and suckering Populus tremuloides and Betula papyrifera) stunted forest tree species (Populus, Betula, Picea glauca, Abies Balsamea), and finally, normal boreal forest flora. Although SO/sub 2/ injury is continuing in this area, these zones now appear to be maintained primarily by ...
In mammals, adult neurogenesis has been extensively studied in the dentate gyrus of the hippocampus and subventricular zone. However, newly proliferated neurons have also been documented in...Full Text Available
An image slicing spectrometer (ISS) for microscopy applications is presented. Its principle is based on the redirecting of image zones by specially organized thin mirrors within a custom fabricated...Full Text Available
In humid zones and marine environments the bio indicator contaminants by trace elements are well established. However, in arid zones it is more difficult to find these tools because there is less biodiversity. The objective of this paper was to analyze the behavior of the Baccharis salicifolia plant in areas with high uranium concentration in arid zones, to determine the characteristics of tolerance and possible use as a bio monitor for the presence of such contaminants. For this project a uraniferous zone was selected in San Marcos, located northwest of the City of Chihuahua. A total of 8 sampling points of the plant and soil were located here. Each sample was divided into the root and the stem and leaves to determine the specific activity of the uranium in both parts of the plant and its sediments. The determination of the specific activities of the total uranium in the samples was obtained by liquid ...
Jun 16, 2011 ... Results indicated that fuel loadings averaged 24.05 Mg ha 1 in 2004–2006. Forest litter decreased from wetter to drier forest life zones. ...
In rats and primates, the central nucleus of the amygdala (CeN) is most known for its role in responses to fear stimuli. Recent evidence also shows that the CeN is required for directing attention...Full Text Available
In multiple sclerosis (MS), oligodendrocyte and myelin destruction lead to demyelination with subsequent axonal loss. Experimental demyelination in rodents has highlighted the activation of the subventricular...Full Text Available
The relationships between soil salinization and the zonal and provincial bioclimatic conditions, the lithological composition of the sediments, and the geomorphic features of the territory have been analyzed for the Southern federal okrug of Russia. It is shown that the lithological and geomorphic conditions (relief, salinity of parent materials, degree of drainage, and the depth of saline groundwater) play an important role in the distribution of salt-affected soils against the background of the more general regularities specified by the climate. The participation of salt-affected soils in the soil cover of the Southern federal okrug increases in the eastward direction from the forest-steppe zone to the semidesert zone in agreement with an increase in the aridity and continentality of the...
Approximately 1.2 million kg of uranium oxide (yellow cake) has been produced from the area surrounding Gunnison, Colorado. Over 99 percent of this has come form the Cochetopa and Marshall Pass districts. Uranium in both districts and many of the other occurrences is associated closely with fault and shear zones which cut brittle host formations (sandstones and dolomites) of Paleozonic and Mesozoic age. Minor uranium occurrences are in pegmatites and shear zones in Precambrian rocks, Cambrian vein material, and sandstones of Tertiary age. In the paper presented, the uranium occurences are described by districts. In addition, possibilities for additional discoveries are discussed. (JMT)
A process for the production of transportation fuels from heavy hydrocarbonaceous feedstock is provided comprising a two-stage, close-coupled process, wherein the first stage comprises a hydrothermal zone into which is introduced a mixture comprising a feedstock and red mud having coke-suppressing and demetalizing activity, and hydrogen; and the second, close-coupled stage comprises a hydrocatalytic zone into which substantially all the effluent from the first stage is directly passed and processed under hydrocracking conditions.
The present paper is concerned with the prediction method for the motions and tensions of mooring lines on slack-moored floating oceanic architectural building in coastal zone. The motions and the tensions of mooring lines were estimated by the time domain numerical simulation in the present method. The present method includes the nonlinearity of mooring system, slow varying wave drift force. The authors performed a time domain numerical simulation for motions and the tensions of mooring lines on floating barge in two component waves. Also, the results obtained by numerical simulation were compared with the experimental results. The validity of the present method was confirmed.
Field experiments were conducted in the 30-km zone of Gomel's region of the Byelorussia to study factors aecting a biological radionuclide accessibility. A contamination density by radiocesium equaled 2,7-9,9 MBk/m"2, strontium 90 - 0,3-0,5 MBk/m"2 in 1991. A sowing of oats barley, lupin was carried out. It was shown that radionuclide accumulation by agricultural plants was determined basically by biological peculiarities of plants in greater degree than by the contamination density. It was shown that strontium 90 migration from the soil was more intensive than that of radiocesium. 8 tabs.
A process for the production of transportation fuels from heavy hydrocarbonaceous feedstock is provided comprising a two-stage, close-coupled process, wherein the first stage comprises a hydrothermal zone into which is introduced a mixture comprising a feedstock and metals-impregnated red mud having coke-suppressing and demetalizing activity, and hydrogen; and the second, close-coupled stage comprises a hydrocatalytic zone into which substantially all the effluent from the first stage is directly passed and processed under hydrocatalytic conditions. The preferred metals for impregnation include transition metals, in particular, nickel and molybdenum.
Friction stir welding of dissimilar formed Mg alloys(AZ31/AZ91) was successfully carried out at the limited welding conditions. In a sound joint, SZ was mainly consisted of AZ31 Mg alloy which was located the retreating side. Dynamic recrystallization and grain growth occurred and {beta} intermetallic compounds of AZ 91 Mg alloy was not observed in SZ. BM had a higher hardness than that of the weld zone. The fracture location was not weld zone but BM of the AZ91 Mg alloy in tensile test. (orig.)
This work deals with the development of wind maps in the Venezuelan coastal zones (South America). The Navier-Stokes equations for real viscous incompressible flow are discretized via the finite element method and they are applied to a full 3D numerical model. Two regions were analyzed: the Margarita island and the Paraguana peninsula, both of them located in the Caribbean Sea at the North of Venezuela. These regions were modeled by using a three dimensional control volume, discretized through hexaedric eight-noded finite elements. Some wind maps obtained in this research are presented and discussed. (author)
We have investigated the properties of nerve cell precursors in hydra by analyzing the differentiation and proliferation capacity of interstitial cells in the peduncle of Hydra oligactis, which is a region of active nerve cell differentiation. Our results indicate that about 50% of the interstitial cells in the peduncle can grow rapidly and also give rise to nematocyte precursors when transplanted into a gastric environment. If these cells were committed nerve cell precursors, one would not expect them to differentiate into nematocytes nor to proliferate apparently without limit. Therefore we conclude that cycling interstitial cells in peduncles are not intermediates in the nerve cell differentiation pathway but are stem cells. The remaining interstitial cells in the peduncle are in G1 and have the properties of committed nerve cell precursors. Thus, the interstitial cell population in the peduncle ...
Poncirin, flavanone glycoside, isolated from the fruit of Poncirus trifoliata, has anti-bacterial and anti-inflammatory activities. In this study, the effects of poncirin on the differentiation of mesenchymal stem cells were investigated. The C3H10T1/2 mesenchymal stem cells and primary bone marrow mesenchymal stem cells were studied. In the C3H10T1/2 cells, poncirin prevented adipocyte differentiation, as demonstrated by inhibition of cytoplasm lipid droplet accumulation and peroxisome proliferator-activating receptor-? (PPAR-?) and CCAAT-enhancer-binding protein-? (C/EBP-?) mRNA expression. By contrast, poncirin enhanced the expression of the key osteogenic transcription factors, runt-related transcription factor 2 (Runx2) and transcriptional coactivator with PDZ-binding motif (TAZ). Poncirin also enhanced expression of the osteogenic marker genes including alkaline phosphatase (ALP) and osteocalcin (OC). Poncirin increased mineral nodule ...
The isotopic composition of Pd, Ag, Cd and Te has been measured by solid source mass spectrometry for four samples from reactor zones 2, 3-4, 5-6 and 7, and from four host rock samples external to the reactor zones from the Oklo mine site. The concentrations of these elements have also been determined in the eight samples using the stable isotope dilution technique. Cumulative fission yields have been derived from the reactor zone samples after correcting where necessary for the terrestrial component of the element concerned. It has been shown that fission-produced Pd and Te are retained almost in their entirety in the uraninite reactor zone samples, whereas a significant fraction of fission-produced Ag and Cd have migrated from the reactor zones. Fission product Cd is observed in the host rock samples, whereas no strong evidence of fission-produced Ag could be found. This the ...
The uncertainty associated with the sorption coefficient, or K{sub d} value, is one of the key uncertainties in estimating risk associated with burying low-level nuclear waste in the subsurface. The objective of this study was to measure >648 K{sub d} values and provide a measure of the range and distribution (normal or log-normal) of radionuclide K{sub d} values appropriate for the E-Area disposal site, within the Savannah River Site, near Aiken South Carolina. The 95% confidence level for the mean K{sub d} was twice the mean in the Aquifer Zone (18-30.5 m depth), equal to the mean for the Upper Vadose Zone (3.3-10 m depth), and half the mean for the Lower Vadose Zone (3.10-18 m depth). The distribution of K{sub d} values was log normal in the Upper Vadose Zone and Aquifer Zone, and normal in the Lower Vadose Zone. To our knowledge, this is the first ...
9 9 simulated Purex waste oxides was investigated as a function of Na/sub 2/O, CaO and P/sub 2/O/sub 5/ content. All compositions lost some sulfate at 50 to 100 deg C above the softening point. In generai the volatility decreased with increase of either Na/ sub 2/O or CaO relative to P/sub 2/O/sub 5/, but no simple correlation Was indicated. Softening temperatures were lowered by inc ease in Na/sub 2/O vs CaO. Ceramic solids were obtained but no true glasses. Attempts to produce glasses by addition of varying combinations of Al/sub 2/O/sub 3/, PbO, BaO, and B/sub 2/O/ sub 3/ to simulated Pure x waste plus phosphite were unsuccessful. The use of 0.005 M Na/sub 2/C/O/sub 3/ to precipitate calcium from wastes containing up to 3 ppm of phosphate was demonstrated in four pilot plant runs and produced a decrease in the hardness of the waste leaving the clarifier. An inadvertent Sr/ sup 90/ and Cs/sup 137/ breakthrough occurred during one run which was caused ...
This paper explores effects of differential diffusion in nonpremixed turbulent jet flames. Pulsed Raman scattering spectroscopy is used to measure temperature and species concentrations in chemically reacting jets of H{sub 2}/CO{sub 2} into air, over a range of jet Reynolds numbers from 1,000 to 30,000 based on cold jet fluid properties. Results show significant effects of differential diffusion at all jet Reynolds numbers considered. Differential diffusion between H{sub 2} and C0{sub 2} produces differences between the hydrogen element mixture fraction ({xi}{sub H}) and the carbon element mixture fraction ({xi}{sub c}). The greatest effects occur on the rich side of stoichiometric, where {xi}{sub H} is observed to be smaller than {xi}{sub C} at all Reynolds numbers. Differential diffusion between H{sub 2} and H{sub 2}O creates a net flux of hydrogen element toward the stoichiometric contour and causes ...
Summary The effects of high-intensity pulsed electromagnetic stimulation (HIPEMS) on proliferation and differentiation of neonatal rat neural stem cells in vitro were investigated. Neural stem cells derived from neonatal rats were exposed to 0.1 Hz, 0.5-10 Tesla (T) [8 groups of B-I, respectively], 5 stimuli of HIPEMF. The sham exposure controls were correspondingly established. Inverted phase contrast microscope was used to observe the cultured cells, MTT assay to detect the viability of the cells as expressed by absorbance (A) value, and flow cytometry to measure differentiation of neural stem cells. The results showed that A values of neural stem cells in both 3.0 T and 4.0 T groups were significantly higher than the other groups 24 to 168 h post HPEMS, indicating a strong promotion of ...
The literature regarding the free vibration analysis of Bernoulli?Euler and Timoshenko beams under various supporting conditions is plenty, but the free vibration analysis of Reddy?Bickford beams with variable cross-section on elastic soil with/without axial force effect using the Differential Transform Method (DTM) has not been investigated by any of the studies in open literature so far. In this study, the free vibration analysis of axially loaded and semi-rigid connected Reddy?Bickford beam with variable cross-section on elastic soil is carried out by using DTM. The model has six degrees of freedom at the two ends, one transverse displacement and two rotations, and the end forces are a shear force and two end moments in this study. The governing differential equations of motion of the r...
Experiments were designed to elucidate whether or not the irradiated bone marrow cells receive any stimulation for the self-replication and differentiation from normal 'stromal' cell colonies in the bone marrow cell culture in vitro. When irradiated or unirradiated bone marrow cells were overlaid on the normal adherent cell colonies, the proliferation of haemopoietic stem cells was supported, the degree of the stimulation depending on the starting cellular concentration. There was, however, no significant changes in the concentration of either CFUs or CFUc regardless of the dose of irradiation on the bone marrow cells overlaid. This was a great contrast to the dose-dependent decrease of CFUs or CFUc within the culture in which both the stem cells and stromal cells were simultaneously irradiated. These results suggest that the balance of self-replication and differentiation of the haemopoietic stem cells is affected only when ...
MRI diagnosis for malignant tumors are made possible by direct comparison to the results obtained by the brain and it seems possible to differentiate malignant tumors from other benign lesions. Cystic lesions, and mycotic sinusitis sometimes resemble malignant tumors in MR Image. In the present report, we investigated the relationships between the biochemical contents of cystic lesions and NMR-parameters to clarify why some inflammatory lesions appeared similar to malignant tumors in MRI. The variation of relaxation time depends upon the amount of protein in the cystic contents and the amount of glucose affects the relaxation time. We conclude that NMR-parameters are useful for the differential diagnosis of malignant tumors, cystic lesions and mycositic sinusitis by using the multiple variation analysis.
In several vertebrate classes, the M?ller glia are capable of de-differentiating, proliferating, and acquiring a progenitor-like state in response to acute retinal injury or in response to exogenous growth factors. Our previous study has shown that M?ller cells can be activated and de-differentiated into retinal progenitors during Royal College of Surgeons (RCS) rats' degeneration, although the limited proliferation cannot maintain retinal function. We now report that rat retinal stem cells (rSCs) transplanted into RCS rats slowed the progression of retinal morphological degeneration and prevented the functional disruption. Further, we found that retinal progenitor cells labeled with Chx10 were increased significantly after rSCs transplantation, and most of them are mainly from activated M...
Human embryonic stem (ES) cells can undergo spontaneously differentiation in standard culture conditions, demonstrating that the undifferentiated state is relatively unstable. The heterogeneous expression of SSEA3 observed within human ES colonies, provides a means to examine undifferentiated stem cell substates. Through functional testing of single cells we have shown that undifferentiated ES cells can be segregated into functionally discrete subpopulations on the basis of SSEA3 expression: SSEA3(High), SSEA(Low) and SSEA3(Negative). Human ES subpopulations were found to be interconvertible, but they possess distinct properties when challenged to differentiate along the neural lineage. These data suggest that ES cells with pluripotent/self-renewal capacities can exhibit different responses to induction of differentiation. PMID:21763622
In the paper the role of conservation laws in evolutionary processes, which proceed in material systems (in material media) and lead to generation of physical fields, is shown using skew-symmetric differential forms. In present paper the skew-symmetric differential forms on deforming (nondifferentiable) manifolds were used in addition to exterior forms, which have differentiable manifolds as a basis. Such skew-symmetric forms (which were named evolutionary ones since they possess evolutionary properties), as well as the closed exterior forms, describe the conservation laws. But in contrast to exterior forms, which describe conservation laws for physical fields, the evolutionary forms correspond to conservation laws for material systems. The evolutionary forms possess an unique peculiarity, namely, the closed exterior forms are obtained from these forms. It is just this that enables one to describe the process of generation ...
As part of the EPRI Motor-Operated Valve (MOV) Performance Prediction Methodology, a System Flow Model (SFM) has been developed to determine the differential pressure (DP) across MOVs as they are stroked in typical power plant systems. Input to the SFM includes valve flow characteristics (such as flow coefficient) and system characteristics (such as pump head/flow curve). The primary output is differential pressure across the valve at each stroke position. The SFM was validated by comparison with test data from the EPRI Flow Loop Test Program. In this study, we calculated DP using SFM and performed DP test for four MOVs. Compared between calculated DP and test DP of four MOV, respectively good agreements are found. (author). 6 refs., 9 figs., 1 tab.
The grey-black mudstones of the Sonehat Formation form part of the Middle Jurassic fill of the Jameson Land Basin in East Greenland. The formation is exposed in the southernmost part of the north south-trending, Mesozoic rift system in East Greenland that was part of the epeiric seaway betaveen East Greenland and Norway. Sedimentological observations of the Sortehat Formation indicate deposition in an offshore marine setting that was typically low energy and periodically oxygen-deficient but was influenced by storm currents on occasion. Detailed palynological studies of the Sortehat Formation have resulted in the definition of theee palynological assemblage zones recognised at four localities, namely Enhjoerningen Dal and Pelion (north Jameson Land), the type section at Sortehat (central Jameson Land) and Albuen at Neill Klinter along Hurry Inlet (south-east Jameson Land). In stratigraphic order, these zones are termed the Botryococcus ...
Regional arterial CO2 tension (PaCO2) reactivity of cerebral blood flow (CBF) and the effect of PaCO2 on the spatial and temporal heterogeneity of CBF were investigated by using autoradiographically determined CBF in the rat middle cerebral artery occlusion model after a 2-h period under pentobarbital anesthesia to clarify the relation between PaCO2 reactivity, CBF heterogeneity, and the temporal cycling of CBF. PaCO2 was adjusted to one of four levels. CBF was determined in four cortical areas and white matter using the tissue fractionation of [14C]iodoantipyrine [( 14C]IAP) in combination with vessel mapping using in vivo 4% thioflavine S. Specific PaCO2 reactivity and CBF were normal in the nonischemic cortex, normal, although slightly depressed, in the border zone far from the ischemic core area, and depressed in the border zone adjacent to the ischemic core area (P less than 0.001) and the ischemic core (P less than 0.001). In normocapnic ...
During development, multipotent neural precursors give rise to oligodendrocyte progenitor cells (OPCs), which migrate and divide to produce additional OPCs. Near the end of embryogenesis and...Full Text Available
BackgroundPuccinia striiformis f. sp. tritici is a fungal pathogen causing stripe rust, one of the most important wheat diseases worldwide. The...Full Text Available
Growing evidence suggests the Wnt family of secreted glycoproteins and their associated signaling pathways, linked to development, are recapitulated during wound repair and regeneration events. However,...Full Text Available
Background: Differentiation between reactive, but morphologically atypical, mesothelial cells and adenocarcinoma in effusions can be problematic. Elaborate immunohistochemical...Full Text Available
The acyl coenzyme A (CoA) binding protein AcbA is secreted unconventionally and processed into spore differentiation factor 2 (SDF-2), a peptide that coordinates sporulation in Dictyostelium...Full Text Available
This paper describes a long term course of research into the fundamentals of two phase flow regime dynamics that had lead to a differential description of regime properties. The development has included experiment, microscale simulation, and mathematical averaging to produce a dynamic equation for interfacial area.
AbstractThe tick-borne protozoan parasite Theileria annulata causes a debilitating disease of cattle called Tropical Theileriosis. The parasite predominantly invades...Full Text Available
Equine herpesvirus type 1 was cultivated in swine testis cell cultures and partially purified by differential centrifugation and centrifugation in a linear sucrose density gradient. The viral envelope...Full Text Available
Mutations in SOX9, a gene essential for chondrocyte differentiation cause the human disease campomelic dysplasia (CD). To understand how SOX9 activates transcription, we characterized...Full Text Available
BackgroundThermogenic brown adipose tissue has never been described in birds or other non-mammalian vertebrates. Brown adipocytes in mammals are distinguished from the more common...Full Text Available
... time, sucrase activity, a marker of intestinal epithelium (Matsushita, 1983) was observed in epithelial cells with CdxA ... PubMed, CSAIshii, Y., K. Fukuda, H. Saiga, S. Matsushita, and S. Yasugi. 1997. E...
BackgroundActivation of the signal transducer and activator of transcription 3 (STAT3) within antigen presenting cells (APCs) is linked to abnormal APCs differentiation and function....Full Text Available
Breast cancer is a leading cause of female deaths worldwide. In Malaysia, it is the most common form of female cancer while Infiltrating ductal carcinoma (IDC) is the most common form of breast cancer....Full Text Available
Recent clinical trials demonstrate that combined oral dosing with estrogen and progestin increases the incidence of breast cancer in post-menopausal women. Similarly, in a rat model system of...Full Text Available
Terminal differentiation of many vascular cells involves cell wall changes. Cells first elongate their primary wall, then lay down a lignified secondary wall, which is often followed by digestion of...Full Text Available
During embryonic development, cells are instructed which position to occupy, they interpret these cues as differentiation programmes, and expand these patterns by growth. Sonic hedgehog...Full Text Available
Constitutive activation of the transcription factor Stat5 in hematopoietic stem/progenitor cells leads to various hematopoietic malignancies including myeloproliferative neoplasm (MPN). Our recent study...Full Text Available
BackgroundRecent evidence suggests that some sex differences in brain and behavior might result from direct genetic effects, and not solely the result of the organizational effects...Full Text Available
Excessive weight loss due to protein calorie malnutrition (PCM) is a significant problem in Nigerian children. This syndrome may be difficult to differentiate from the wasting disease caused by human...Full Text Available
... from Dr. Austin Smith of the Institute for Stem Cell Research, University of Edinburgh) was modified from the CGR8 ... to thank Dr. Austin Smith, the Institute for Stem Cell Research, University of Edinbu...
Adipocyte differentiation is a complex developmental process that involves the coordinated interplay of numerous transcription factors. PPARγ has emerged as a master regulator of adipogenesis...Full Text Available
• Background and Aims Development and architecture of plant roots are regulated by phytohormones. Cytokinin (CK), synthesized in the root cap, promotes cytokinesis, vascular...Full Text Available
The level of bone morphogenetic protein 2 (BMP2) profoundly influences essential cell behaviors such as proliferation, differentiation, apoptosis, and migration. The spatial and temporal pattern...Full Text Available
BackgroundLung cancer diagnosis in tissue material with commonly used histological techniques is sometimes inconvenient and in a number of cases leads to ambiguous conclusions. Frequently...Full Text Available
Some pathological conditions with feeding pattern alterations, including obesity and Huntington disease (HD) are associated with hypothalamic dysfunction and neuronal cell death. Additionally, the hypothalamus...Full Text Available
The development of three-dimensional (3D) biomimetic scaffolds which provide an optimal environment for cells adhesion, proliferation and differentiation, and guide new tissue formation has...Full Text Available
We examined the effect of spatial iconicity (a perceptual simulation of canonical locations of objects) and word-order frequency on language processing and episodic memory of orientation. Participants...Full Text Available
... be rare or absent as leaves in the forest litter. The differences between the amount of leaf and ... the relative proportions of leaf species in a forest litter when compared with standing biomass has sig...
It is generally accepted that hypoxia and recovery from oxygen deprivation contribute to the breakdown and ulceration of human skin. The effects of these stresses on proliferation, differentiation...Full Text Available
On the basis of the resolvent of a simple differential operator, a method for finding approximations to continuous functions is constructed. In this method, both the approximated function and its approximations satisfy the given integral boundary condition.
We study a rapidly convergent modification of a two-sided method for the approximate integration of a boundary-value problem with parameters in boundary conditions for a system of quasilinear second-order differential equations.
BackgroundStem cell characteristics are an important feature of human cancer cells and play a major role in the therapy resistance of tumours. Strategies to target cancer stem cells...Full Text Available
Ionotropic P2X and metabotropic P2Y purinergic receptors are expressed in the central nervous system and participate in the synaptic process particularly associated with acetylcholine, GABA, and glutamate...Full Text Available
BackgroundIn rats, alcohol exposure during the period of rapid brain growth produces long-term changes in the free-running period, photoentrainment and phase-shifting...Full Text Available
A highly purified preparation of double-stranded RNA, obtained from virus-like particles in Penicillium cultures, was found to affert humoral immune responses in mice differentially depending on its...Full Text Available
In our quest for novel genes required for the development of the embryonic peripheral nervous system (PNS), we have performed three genetic screens using MAb 22C10 as a marker of terminally differentiated...Full Text Available
Calpains are Ca2+-dependent proteinases that mediate protein turnover in crustacean skeletal muscles. We used an antibody directed against lobster muscle-specific calpain (Ha-CalpM)...Full Text Available
Genes of the S100 fused-type protein (SFTP) family are clustered within the epidermal differentiation complex and encode essential components that maintain epithelial homeostasis and barrier functions....Full Text Available
3T3 - L1 cells can be induced to differentiate by exposing cell culture to a medium containing 3-isobutyl-1-methyl-xanthine together with insulin and dexamethasone. They have observed that oxalomalate (OMA) which inhibits aconitase thus blocking the citric cycle, also favours differentiation to adipocytes leading to fatty acids accumulation and increased synthesis of specific proteins. They compared the effects of 3-isobutyl-1-methyl-xanthine-insulin-dexamethasone and OMA on the steady-state levels of mRNA of c / EBP, H-ferritin and aconitase / IRE-BP. OMA does not affect the steady-state mRNA amount of C / EBP, H-ferritin and aconitase / IRE-BP but the 3-isobutyl-1-methyl-xanthine-insulin-dexamethasone mixture is able to induce a five-fold increase of mRNA levels for aconitase / IRE-BP. This is the first finding correlating iron metabolism to adipocyte differentiation. Further studies will clarify a possible role for the ...
The cosmic ray neutron spectrum at sea level has been measured by the method of pulse shape discrimination in anthracene scintillator. The exponent of the differential spectrum was found to be 2.2+-0.1. (Auth.).
IntroductionNormal and neoplastic breast tissues are comprised of heterogeneous populations of epithelial cells exhibiting various degrees of maturation and differentiation. While...Full Text Available
BackgroundThe epidermal growth factor receptor (Egfr) with its numerous ligands has fundamental roles in development, cell differentiation and physiology. Dysfunction of the receptor-ligand...Full Text Available
Circuit modification associated with learning and memory involves multiple events, including the addition and remotion of newborn cells trough adulthood. Adult neurogenesis and gliogenesis were mainly...Full Text Available
A large temperature differential (10K) thermal storage system in a small (4400 m{sup 2}) 8-storey office building is discussed and the monitoring results are analyzed in comparison with computer simulations. Requirements were a comfortable indoor environment and system cost effectiveness. Out of four potential system concepts, the Large Temperature Differential System was chosen. It comprises a flat-type thermal stratification heat storage tank in the under floor pit of the building as the heat source for a variable flow heat pump chiller. The heat sink is a set of serially connected air handling and fan coil units. The tank`s capacity is sized for one day operation and is made as large as possible to shift the electricity demand to night time. To avoid a large size and high cost, the water temperature differential was enlarged. The role of Tokyo Electric Power Company (TEPCO) was to develop the chiller and its control ...
The promising use of mesenchymal stromal cells (MSC) in regenerative technologies accounts for necessity of detailed study of their physiology. Proliferation and differentiation of multipotent cells often involve changes in their metabolic state. In the present study, we analyzed the expression of ATP-sensitive potassium (K"A"T"P) channels in MSC and upon in vitro differentiation. K"A"T"P channels are present in many cells and regulate a variety of cellular functions by coupling cell metabolism with membrane potential. Kir6.1, Kir6.2 and SUR2A were expressed in undifferentiated MSC, whereas SUR2B and SUR1 were not detected on cDNA and protein level. Upon adipogenic differentiation Kir6.1 and SUR2A showed a significant reduction of the amount of mRNA by 84% and 95%, respectively, whereas Ki...
Patients with schizophrenia can be taught the Wisconsin Card Sorting Test (WCST) sorting rules based upon expanded feedback. However, few task manipulations have been reported that differentially...Full Text Available
The intramembrane aspartyl protease γ-secretase plays a fundamental role in several signaling pathways involved in cellular differentiation and has been linked with a variety of human diseases,...Full Text Available
Membranous dysmenorrhea is an unusual clinical entity. It is characterized by the expulsion of huge fragments of endometrium during the menses, favored by hormonal abnormality or drug intake. This report describes a case with clinical, US, and MRI findings before the expulsion. Differential diagnoses are discussed. (orig.)
Skeletal formation is an essential and intricately regulated part of vertebrate development. Humans and mice deficient in Growth and Differentiation Factor 6 (Gdf6) have numerous...Full Text Available
BackgroundThe hard clam, Mercenaria mercenaria, has been affected by severe mortality episodes associated with the protistan parasite QPX (Quahog Parasite Unknown)...Full Text Available
The methods of statistical dynamics are applied to a fluid with 5 conserved fields (the mass, the energy, and the three components of momentum) moving in a given external potential. When the potential is zero, we recover a previously derived system of parabolic differential equations, called "corrections to fluid dynamics".
BackgroundStem cells divide to reproduce themselves and produce differentiated progeny. A fundamental problem in human biology has been the inability to measure how often stem cells...Full Text Available
Accumulation of molecular damage and increased molecular heterogeneity are hallmarks of cellular aging. Mild stress-induced hormesis can be an effective way for reducing the accumulation of molecular...Full Text Available
BackgroundHuman Papillomavirus (HPV) E2 plays several important roles in the viral cycle, including the transcriptional regulation of the oncogenes E6 and E7, the regulation of the...Full Text Available
The glycolipid content of human non-seminomatous germ cell tumour cell lines correlates with their differentiation lineage. To analyse whether this reflects the situation in primary tumours, we studied...Full Text Available
One of the major decisions that germ cells make during their development is whether to differentiate into oocytes or sperm. In mice, the germ cells’ decision to develop as male or female depends...Full Text Available
Quantitative probing of heterogeneous regions in muscle is feasible with phosphorus-31 magnetic resonance spectroscopy because of the differentiation of metabolic patterns of glycolytic and oxidative...Full Text Available
Background:Stem cells can differentiate into multiple cell types, and therefore can be used for cellular therapies, including tissue repair. However, the participation of stem cells...Full Text Available
Tendon reconstruction using grafts often results in adhesions that limit joint flexion. These adhesions are precipitated by inflammation, fibrosis, and paucity of tendon differentiation signals...Full Text Available
Background & objectives:Acanthamoeba keratitis (AK) is a painful and vision-threatening ocular infection. The differentiation of Acanthamoeba...Full Text Available
Fear learning is associated with changes in synapse strength in the lateral amygdala (LA). To examine changes in LA dendritic spine structure with learning, we used serial electron microscopy to re-construct...Full Text Available
Fibroblast growth factor (FGF) signaling is involved in skeletal development of the vertebrate. Gain-of-function mutations of FGF receptors (FGFR) cause craniosynostosis, premature fusion of the skull,...Full Text Available
Silent information regulators are potent NAD+-dependent protein deacetylases, which have been shown to regulate gene silencing, muscle differentiation and DNA damage repair. Here,...Full Text Available
Bistability plays a central role in the gene regulatory networks (GRNs) controlling many essential biological functions, including cellular differentiation and cell cycle control. However, establishing...Full Text Available
Mitogen Activated Protein Kinases (MAPKs) are a class of serine/threonine kinases that regulate a number of different cellular activities including cell proliferation, differentiation, survival and...Full Text Available
Low kVp settings provide high conspicuity of contrast materials at CT but may result in high image noise, particularly in larger patients. Material decomposition at dual energy CT can differentiate...Full Text Available
Spatial abilities have been associated with many ecologically-relevant behaviors such as territoriality, mate choice, navigation and acquisition of food resources. Differential demands on spatial...Full Text Available
We have isolated a second gene (MLS1), which in addition to DAL7, encodes malate synthase from S. cerevisiae. Expression of the two genes is specific for their physiological roles in carbon and nitrogen...Full Text Available
The Tetrahymena thermophila origin recognition complex (ORC) contains an integral RNA subunit, 26T RNA, which confers specificity to the amplified ribosomal DNA (rDNA) origin by base...Full Text Available
A stain of 0.1% toluidine blue in a 1.0% aqueous solution of triethylene glycol followed by decolorization with acid-alcohol resulted in mycobacteria retaining the stain (violet), whereas non-acid-fast...Full Text Available
Retinoic acid inducible gene I (RIG-I) is a pattern recognition receptor (PRR) responsible for detection of nucleic acids from pathogens in the cytoplasm of infected cells and induction of type I interferon...Full Text Available
IntroductionTyrosine phosphorylated signal transducer and activator of transcription 3 (pStat3) is expressed in numerous cancers and is required for mediating tumorigenesis. Autocrine...Full Text Available
Normal mouse epidermis constitutively expresses prostaglandin-H synthase 1 (PGHS-1) but no PGHS-2. Acute inflammation and epidermal hyperplasia, (hyperplastic transformation), as evoked in adult mouse...Full Text Available
BackgroundFor the clinical management of adrenocortical neoplasms it is crucial to correctly distinguish between benign and malignant tumours. Even histomorphologically based scoring...Full Text Available
Haemophilus parasuis is an important opportunistic pathogen in swine of high health status, but to date no proven virulence factors have been described. As virulence factors are known...Full Text Available
Whereas genetic factors are known to influence both susceptibility to carcinogens and the capacity to respond to specific antigenic stimuli, little is known regarding the influence of phenotype per...Full Text Available
BackgroundMultidrug resistance (MDR) is a major obstacle in cancer treatment and is often the result of overexpression of the drug efflux protein, P-glycoprotein (P-gp), as a consequence...Full Text Available
BackgroundThough long known to affect smooth muscle biology, recent studies indicate that phosphodiesterase 5 (PDE5) is also expressed in myocardium. Recognizing that the regulation...Full Text Available
Acetaminophen (APAP), a widely used analgesic and antipyretic that is considered to be relatively safe at recommended doses, is the leading cause of drug-induced liver failure in the United States....Full Text Available
Although skin is usually exposed during human exposures to ionizing radiation, there have been no thorough examinations of the transcriptional response of skin fibroblasts and keratinocytes...Full Text Available
Growth at increasing continuous irradiance (at high nutrient nitrate) and nutrient nitrate concentrations (at high continuous irradiance) furnished increases in the in vivo and in...Full Text Available
BackgroundRed ripe tomatoes are the result of numerous physiological changes controlled by hormonal and developmental signals, causing maturation or differentiation of various fruit...Full Text Available
Normal reproductive functioning may require secretion of LH independently of FSH. Variation in GnRH pulse frequency and inhibin negative feedback are mechanisms for differential gonadotropin regulation;...Full Text Available
Thermal behaviors of eucalyptus wood residue (EWR) filled recycled high density polyethylene (HDPE) composites have been measured applying the thermogravimetric analysis (TGA) and differential scanning...Full Text Available
Real-time PCR has the potential to streamline detection and identification of Cryptosporidium spp. in human clinical samples. In the present...Full Text Available
We investigate the default time of a firm when a stochastic discount factor is used so that both diffusion and regime switching risks are priced. We establish the relationship between the probability distribution of the default time and the solution of a system of coupled partial differential equations.
SummaryHuman skin expresses elements of the hypothalamo-pituitary-adrenal (HPA) axis including pro-opiomelanocortin (POMC), corticotropin releasing hormone (CRH), the CRH receptor-1...Full Text Available
Cryptococcus neoformans is a ubiquitously distributed human pathogen. It is also a model system for studying fungal virulence, physiology and differentiation. Light is known to inhibit...Full Text Available
Normal healthy volunteers underwent broncho-alveolar lavage and the cells obtained were cultured for 24 h and 48 h, either alone or in the presence of the corticosteroid, Budesonide. Cell differentials...Full Text Available
BACKGROUND: H2-histamine receptors mediate a wide range of physiological functions extending from stimulation of gastric acid secretion to induction of human promyelocyte differentiation. We have previously...Full Text Available
Our understanding of the development of neurotransmitter systems in the central nervous system has increased greatly over the past three decades and it has become apparent that drug effects...Full Text Available
BackgroundWhite spot syndrome (WSS) is a viral disease that affects most of the commercially important shrimps and causes serious economic losses to the shrimp farming industry worldwide....Full Text Available
Mechanisms for differential regulation of gene expression may underlie much of the phenotypic variation and adaptability of malaria parasites. Here we describe transcriptional variation among culture-adapted...Full Text Available
In a previous study we found that nanofibrous poly(l-lactic acid) (PLLA) scaffolds mimicking collagen fibers in size were superior to solid-walled scaffolds in promoting osteoblast differentiation...Full Text Available
Mechanisms regulating sexual differentiation of the zebra finch song system appear to include both genetic and hormonal factors. Sorting Nexin 2 (SNX2), which is involved in trafficking proteins...Full Text Available
IntroductionAutologous chondrocyte transplantation (ACT) is a routine technique to regenerate focal cartilage lesions. However, patients with osteoarthritis (OA) are lacking an appropriate...Full Text Available
Organisms belonging to the genus Streptomyces produce numerous important secondary metabolites and undergo a sophisticated morphological differentiation program. In many instances these...Full Text Available
The role of intracellular Ca2+ (Ca2+i) on hematopoiesis was investigated in long term bone marrow cultures using cytokines and agonists of P2 receptors. Cytokines interleukin 3 and granulocyte/macrophage colony stimulator factor promoted a modest increase in Ca2+i concentration ([Ca2+]i) with activation of phospholipase Cgamma, MEK1/2, and Ca2+/calmodulin kinase II. Involvement of protein kinase C was restricted to stimulation with interleukin 3. In addition, these cytokines promoted proliferation (20 times) and an increase in the Gr-1(-)Mac-1+ population with participation of gap junctions (GJ). Nevertheless ATP, ADP, and UTP promoted a large increase in [Ca2+]i, moderate proliferation (6 times), a reduction in the primitive Gr-1(-)Mac-1(-)c-Kit+ population, and differentiation into macrophages without participation of GJ. It is likely that Ca2+i participates as a regulator of hematopoietic signaling: moderate increases in [Ca2+]i would be related to ...
SummarySpatial control of gene expression, at the level of both transcription and translation, is critical for cellular differentiation [1-Full Text Available
Delineating the differential effects of anxiety versus depression on patterns of information processing has proved challenging. The tripartite model of mood disorders (Clark...Full Text Available
Differential scanning calorimetric (DSC) studies of the glassy states of as-received and hydrated lysozyme, hemoglobin, and myoglobin powders, with water contents of < or = 0.25, < or...Full Text Available
The polymorphic phase behavior of a homologous series of n-saturated 1,2-diacyl phosphatidylethanolamines was investigated by differential scanning calorimetry, 31P-nuclear magnetic resonance, and Fourier...Full Text Available
To examine the associations between body weight and physical, verbal, relational and cyber victimization among U.S. boys and girls in grade 6 through 10. Underweight boys and girls were more...Full Text Available
Total and differential leucocyte counts were measured in cord blood samples obtained by cordocentesis (n = 316) or at elective caesarean section (n = 11) from normal fetuses of between 18 and 40 weeks'...Full Text Available
Although salamanders are characteristic amphibians in Holarctic temperate habitats, in tropical regions they have diversified evolutionarily only in tropical America. An adaptive radiation centered...Full Text Available
Arabidopsis thaliana SUPERMAN (SUP) plays an important role during flower development by maintaining the boundary between stamens and carpels in the inner two whorls....Full Text Available
ObjectiveThis study sought to determine whether differential treatment effects in the targeted mechanisms of change and eating disorder (ED) symptoms are associated...Full Text Available
The authors present differential scanning calorimetry (DSC) and in situ Moessbauer spectroscopy results for Metglas ribbons, to which different heat treatments were made. The Curie temperature of the amorphous phase is determined and the evolution of the magnetic field of this phase is studied as a function of temperature
Among the several rotenoids, amorphigenin is isolated from the leaves of Amopha Fruticosa and it is known that has anti-proliferative effects and anti-cnacer effects in many cell types....Full Text Available
Ozone (O3) is an oxidant gas that can directly induce lung injury. Knowledge of the initial molecular events of the acute O3 response would be useful in developing biomarkers of...Full Text Available
BackgroundObesity is one of the principal causative factors involved in the development of metabolic syndrome. AMP-activated protein kinase (AMPK) is an energy sensor that regulates...Full Text Available
KLF1 regulates a diverse suite of genes to direct erythroid cell differentiation from bipotent progenitors. To determine the local cis-regulatory contexts and transcription factor networks...Full Text Available
... on the presence of leukocytes in the mammary epithelial tissue [11], temporal differentiation of the epithelial cells during ... of the gland and were separated from the epithelial tissue by bundles of co...
Previous studies have been conducted in gene expression profiling to identify groups of genes that characterize the colorectal carcinoma disease. Despite the success of previous attempts to identify...Full Text Available
Motivation: The identification of gene regulatory modules is an important yet challenging problem in computational biology. While many computational methods have been proposed to identify...Full Text Available
This plan details the methods and procedures necessary to ensure a safe transition in the operation of the Light Duty Utility Arm (LDUA) System. The steps identified here outline the work scope and identify responsibilities to complete startup, and turnover of the LDUA to Characterization Project Operations (CPO).
While genomic alterations identified in human tumors using techniques such as comparative genomic hybridisation (CGH) may be recurrent, they frequently encompass large regions, in some cases...Full Text Available
The development of a computational intelligent tools based on neural network to identify commercial losses or fraud (theft energy), considering information from a database electric utility, is presented.
A method to identify hadronic molecules in the particle spectrum is reviewed and the conditions for its applicability discussed. Special emphasis is put on the discussion of molecule candidates in the baryon spectrum. (orig.)
Descriptive assessment methods have been used in applied settings to identify consequences for problem behavior, thereby aiding in the design of effective treatment programs. Consensus has not been...Full Text Available
Cancers are highly heterogeneous and contain many passenger and driver mutations. To functionally identify tumor suppressor genes relevant to human cancer, we compiled pools of short harpin...Full Text Available
Large-scale cancer genome projects will soon be able to sequence many cancer genomes to comprehensively identify genetic changes in human cancer. Genome-wide association studies have also identified...Full Text Available
...dates of the implementation of the standard unique health identifier for health care providers. 162.404 Section 162.404 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES ADMINISTRATIVE DATA...
This paper is concerned with the study of insurance related derivatives on financial markets that are based on non-tradable underlyings, but are correlated with tradable assets. We calculate exponential utility-based indifference prices, and corresponding derivative hedges. We use the fact that they can be represented in terms of solutions of forward-backward stochastic differential equations (FBSDE) with quadratic growth generators. We derive the Markov property of such FBSDE and generalize results on the differentiability relative to the initial value of their forward components. In this case the optimal hedge can be represented by the price gradient multiplied with the correlation coefficient. This way we obtain a generalization of the classical 'delta hedge' in complete markets.
The purpose of this study is to clarify the confusing nomenclature and pathogenesis of Developmental Facial Paralysis, and how it can be differentiated from other causes of facial paralysis present at birth. Differentiating developmental from traumatic facial paralysis noted at birth is important for determining prognosis, but also for medicolegal reasons. Given the dramatic presentation of this condition, accurate and reliable guidelines are necessary in order to facilitate early diagnosis and initiate appropriate therapy, while providing support and counselling to the family. The 30 years experience of our center in the management of developmental facial paralysis is dependent upon a thorough understanding of facial nerve embryology, anatomy, nerve physiology, and an appreciation of well...