Energy Technology Data Exchange (ETDEWEB)

We aim to isolate cDNAs mapping to human chromosome 16 and localise such cDNAs on the high resolution physical map. In collaboration with LANL, PCR primers will be synthesised from cDNA sequences mapped to chromosome 16 and used as ESTs in the generation of mega-YAC contigs for this chromosome. Probing of high density cosmid grids will enable integration of the ESTs into cosmid contigs and location of the cosmid contigs on the YAC contig. A hn-cDNA library has been constructed from the hybrid CY18 which contains chromosome 16 as the only human chromosome. A modified screening protocol has been successfully developed and 15 hn-cDNA clones have been sequenced and localised on the hybrid map. Sequence analysis of four of these revealed that they were known cDNAs, which are now mapped to chromosome 16. Development of techniques to allow the isolation of longer cDNAs ...

Energy Technology Data Exchange (ETDEWEB)

The Chediak-Higashi syndrome (CHS) is a severe autosomal recessive condition, features of which are partial oculocutaneous albinism, increased susceptibility to infections, deficient natural killer cell activity, and the presence of large intracytoplasmic granulations in various cell types. Similar genetic disorders have been described in other species, including the beige mouse. On the basis of the hypothesis that the murine chromosome 13 region containing the beige locus was homologous to human chromosome 1, we have mapped the CHS locus to a 5-cM interval in chromosome segment 1q42.1-q42.2. The highest LOD score was obtained with the marker D1S235 (Z{sub max} = 5.38; {theta} = 0). Haplotype analysis enabled us to establish D1S2680 and D1S163, respectively, as the telomeric and the centromeric flanking markers. Multipoint linkage analysis confirms the localization of the CHS locus in this interval. Three YAC clones were found to cover the entire region in a ...

Energy Technology Data Exchange (ETDEWEB)

A gene designated BRCA1, implicated in the susceptibility to early-onset familial breast cancer, has recently been localized to chromosome 17q12-q21. To date, the order of DNA markers mapped within this region has been based on genetic linkage analysis. The authors report the use of multicolor fluorescence in situ hybridization to establish a physically based map of five polymorphic DNA markers and 10 cloned genes spanning this region. Three cosmid clones and Alu-PCR-Generated products derived from 12 yeast artificial chromosome clones representing each of these markers were used in two-color mapping experiments to determine an initial proximity of markers relative to each other on metaphase chromosomes. Interphase mapping was then employed to determine the order and orientation of closely spaced loci by direct visualization of fluorescent signals following hybridization of three probes, each detected in a different color. Statistical analysis of the combined data ...

Energy Technology Data Exchange (ETDEWEB)

The authors describe a cloning strategy for the construction of a human genomic library in yeast artificial chromosomes (YACs) based on complete digestion of high-molecular-weight DNA with the infrequently cutting restriction enzyme MluI. Cloning of MluI fragments in the vector pYAC-RC and one subsequent size fractionation by preparative pulsed-field gel electrophoresis yielded a library with average insert sizes of 600 kb. Ninety-seven percent of the colonies were recombinant. An additional size fractionation of MluI fragments prior to ligation had no significant influence on the size of the YACs. The library currently consists of 5000 clones, which is the equivalent of one human genome. Nineteen percent of the YACs were larger than 1.2 Mb. Since smaller MluI fragments are lost during sizing, they also performed cloning without size fractionation. Only 20% of the colonies were recombinant, probably due ...

Energy Technology Data Exchange (ETDEWEB)

Chapter 5, describes some of the most important molecular methods used in the study of chromosome structure and function. The methods discussed include fragmentation of DNA, cloning, flow cytometry and chromosome sorting, is situ hybridization, polymerase chain reaction (PCR), and yeast artificial chromosomes (YACs). 18 refs., 3 figs., 1 tab.

British Library Electronic Table of Contents (United Kingdom)

To study interactions between plants and plant-parasitic nematodes, several omics studies have nowadays become extremely useful. Since most data available so far is derived from sedentary nematodes, we decided to improve the knowledge on migratory nematodes by studying the transcriptome of the nematode Pratylenchus coffeae through generating expressed sequence tags (ESTs) on a 454 sequencing platform. In this manuscript we present the generation, assembly and annotation of over 325,000 reads from P. coffeae. After assembling these reads, 56,325 contigs and singletons with an average length of 353bp were selected for further analyses. Homology searches revealed that 25% of these sequences had significant matches to the Swiss-prot/trEMBL database and 29% had significant matches in nematode E...

Energy Technology Data Exchange (ETDEWEB)

Genetic mapping is approached using the techniques of high resolution fluorescence in situ hybridization (FISH). This technology and the results of its application are designed to rapidly generate whole genome as tool box of expressed sequence to speed the identification of human disease genes. The results of this study are intended to dovetail with and to link the results of existing technologies for creating backbone YAC and genetic maps. In the first eight months, this approach generated 60--80% of the expressed sequence map, the remainder expected to be derived through more long-term, labor-intensive, regional chromosomal gene searches or sequencing. The laboratory has made significant progress in the set-up phase, in mapping fetal and adult brain and other cDNAs, in testing a model system for directly linking genetic and physical maps using FISH with small fragments, in setting up a database, and in establishing the validity and throughput of the system.

Science.gov (United States)

ratio 2 with NACA 0005-63 thickness distribution in streamwise planes, and twisted and cambered for a trapezoidal span load distribution has ...

Science.gov (United States)

The satellite ocean color data record spans multiple decades and, like most long-term satellite

Science.gov (United States)

of Aspect Ratio 2 With NACA 0005-63 Thickness Distribution,. Cambered and Twisted for a Trapezoidal Span Load Distribution. NACA RM A50K27a,, ...

UK PubMed Central (United Kingdom)

A multiple comparison approach using whole genome transcriptional arrays was used to identify genes and pathways involved in calorie restriction/dietary restriction (DR) life span extension in Drosophila....Full Text Available

UK PubMed Central (United Kingdom)

Here we use published 16S rRNA gene sequences to compare the bacterial assemblages associated with humans, other mammals, other metazoa, and free-living microbial communities spanning a range...Full Text Available

UK PubMed Central (United Kingdom)

SummaryThe life span of C. elegans can be increased via reduced function of the mitochondria; however, the extent to which mitochondrial alteration in a single,...Full Text Available

UK PubMed Central (United Kingdom)

Integration of solid-state biosensors and lipid bilayer membranes is important for membrane protein research and drug discovery. In these sensors, it is critical that the solid-state sensing...Full Text Available

Science.gov (United States)

No Abstract Available

UK PubMed Central (United Kingdom)

BackgroundIn a previous study conducted at the Cesare Maltoni Cancer Research Center of the European Ramazzini Foundation (CMCRC/ERF), we demonstrated for the first time that aspartame...Full Text Available

UK PubMed Central (United Kingdom)

Hyperglycemia and hyperinsulinemia accelerate both aging and cancer. Antidiabetic biguanides such as metformin decrease glucose, insulin and IGF-1 level. Metformin increases lifespan and prevents cancer...Full Text Available

UK PubMed Central (United Kingdom)

The hypothesis, that a decrease in metabolic rate mediates the life span prolonging effect of caloric restriction (CR), was tested using two strains of mice, one of which, C57BL/6, exhibits...Full Text Available

Science.gov (United States)

much in common. For starters, Isabel was hundreds of miles across, while M51 (the Whirlpool Galaxy) spans about 50,000 light-years making them vastly dissimilar in scale, not...

British Library Electronic Table of Contents (United Kingdom)

Design rules for robustness require insensitivity to local failure and the prevention of progressive collapse. This is often verified by applying the load case ''removal of a limited part of the structure''. This paper will evaluate typical structural systems for large-span timber roof structures against these requirements, comparing the results against typical reasons for damages and failures. Applying the finding that most failures of timber structures are not caused by random occurrences or local defects, but by global (repetitive) defects (e.g. from systematic mistakes), it is shown that the objective of load transfer-often mentioned as preferable-should be critically analysed for such structures. Based on these findings, proposals for structural systems and details towards a robust de...

Energy Technology Data Exchange (ETDEWEB)

This paper shows some considerations about the cost of wood, steel and cement support pillars in rural power distribution systems. The life span, mechanical properties, cost estimation and general durability of each type of pillar was evaluated, aiming a better selection of the desired one. 6 figs., 8 tabs., 4 refs.

International Nuclear Information System (INIS)

Beagle dogs given a single inhalation exposure to "2"3"9Pu(NO_3)_4 are being observed for life-span dose-effect relationships. Over half of the dogs planned for "2"3"9Pu(NO_3)_4 exposure have been exposed and the remaining dogs will be exposed as they reach adult age.

UK PubMed Central (United Kingdom)

Human Fas/Apo-1 is a cell-surface protein that mediates apoptosis upon ligation with Fas ligand. The gene lies on the long arm of chromosome 10, consists of nine exons, and spans more than 26 kb of...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Mutations in the mouse formin (Fmn) gene, formerly known as the limb deformity (ld) gene, give rise to recessively inherited limb deformities and renal malformations or aplasia. The Fmn gene encodes many differentially processed transcripts that are expressed in both adult and embryonic tissues. To study the genomic organization of the Fmn locus, we have used Fmn probes to isolate and characterize genomic clones spanning 500 kb. Our analysis of these clones shows that the Fmn gene is composed of at least 24 exons and spans 400 kb. We have identified two novel exons that are expressed in the developing embryonic limb bud as well as adult tissues such as brain and kidney. We have also used a microsatellite polymorphism from within the Fmn gene to map it genetically to a 2.2-cM interval between D2Mit58 and D2Mit103. 36 refs., 6 figs., 1 tab.

Energy Technology Data Exchange (ETDEWEB)

As a consequence of the expanded use of long term hemodialysis and continuous ambulatory peritoneal dialysis (CAPD) treatments and extended life spans, complications of end-stage renal disease and dialysis treatments are being encountered with increasing frequency in these patients. Computed tomography can accurately depict many of the potential complications of end-stage renal disease on dialysis. This article presents the abdominal CT findings of 429 end-stage renal disease patients who are on either hemodialysis or continuous ambulatory peritoneal dialysis treatment.

Energy Technology Data Exchange (ETDEWEB)

E. coli HB101 cells transformed to tetracycline resistance with the plasmids pMB9 or pBR322 display a 10/sup 5/-10/sup 6/-fold lower plating efficiency on agar containing 440 ..mu..M CdCl/sub 2/ than nontransformed cells. When DNA is inserted into the BamH1 site of the plasmid tet gene, or when DNA spanning the BamH1 site is deleted, tetracycline resistance and cadmium hypersensitivity are both lost. In contrast, insertion of DNA into the ampicillin resistance gene does not affect cadmium hypersensitivity.

Energy Technology Data Exchange (ETDEWEB)

The contribution under consideration spans a wide curve from the first deadly accident of motorized aviation in the year 1908 up to newer tendencies of the so-called team resources management on observation points and control stations in order to pursue fundamental questions in man-machine systems. A continuous differentiation in the consideration of the factor human beings in complex technical systems is described. This is illustrated by the example of concepts for leadership, communication and decision making on observation points and control stations.

British Library Electronic Table of Contents (United Kingdom)

In a quantitative survey of religious attitudes and practices in a multi-religious sample of 369 school pupils aged between 13 and 15 in London, the presence of a home shrine was found widespread in 11% of adolescents spanning several religious affiliations and ethnicities - especially Buddhists, Hindus and those of Indian, Chinese and 'Other Asian' ethnicity. Having a home shrine correlated significantly with spiritual attitudes such as agreement with filial piety, the Eightfold Path, subjectivity of happiness, meditation, Sikh festivals, reincarnation and opening Gurdwaras to all. It is suggested that teachers and the social services should be aware of the importance of shrines to many religious communities and recognise their potential as a spiritual asset and manifestation of religion ...

Energy Technology Data Exchange (ETDEWEB)

The goal of the book is to summarize those methods for evaluating Feynman integrals that have been developed over a span of more than fifty years. The book characterizes the most powerful methods and illustrates them with numerous examples starting from very simple ones and progressing to nontrivial examples. The book demonstrates how to choose adequate methods and combine evaluation methods in a non-trivial way. The most powerful methods are characterized and then illustrated through numerous examples. This is an updated textbook version of the previous book (Evaluating Feynman integrals, STMP 211) of the author. (orig.)

British Library Electronic Table of Contents (United Kingdom)

The establishment of workable collaborative relations with indigenous elites formed a vital part of the maintenance of the British Empire. This was especially so in the Malay States, where the Malay rulers enjoyed considerable local prestige as religious leaders and as the organising principle of Malay society itself. As the case of Sultan Ibrahim of Johore demonstrates, nevertheless, indigenous collaborators were no mere puppets and enjoyed considerable freedom of action to frustrate and impede the policies of their imperial overlords. Sultan Ibrahim presents a particularly interesting case study as his 64-year reign more or less spanned the entire period of formal British rule in Malaya.

Science.gov (United States)

This paper presents a semi-active vibration control of a scaled two-span bridge structure. Magneto-rheological fluid dampers are utilized as the semi-active energy absorbing deices and a bridge vibration control system is developed. Closed-loop control system based on fuzzy logic is used to suppress the bridge deck motion under random excitations. The sufficient condition for the closed-loop stability of the fuzzy control system is derived from the variable structure system theory. It is demonstrated that this stable fuzzy control system can significantly reduce the relative deck displacement using about 55 percent less power compared to passive-on state, while the absolute deck acceleration is relatively unaffected.

British Library Electronic Table of Contents (United Kingdom)

The Huqf Supergroup of the Sultanate of Oman provides important information on the geological evolution of the Arabian?Persian Gulf region during a protracted period of continental dispersal and reassembly on the periphery of the Gondwanan supercontinent during the Neoproterozoic, and also provides important constraints on the nature of extreme climate swings during this critical period in the evolution of Earth's biosphere. The Huqf Supergroup spans the period ca. 725?540?Ma, and is composed of three groups. The Abu Mahara Group (ca. 725 to ca.ca. 547?540?Ma), which is known mostly from the subsurface, comprises carbonates, evaporites and organic-rich shales, with interbedded ashes, deposited in a large number of N?S trending troughs and platforms.The three groups of the Huqf Supergroup c...

Energy Technology Data Exchange (ETDEWEB)

A sample of 30 manganese-exposed foundry workers from two Swedish plants were examined with a partly computerized psychological test battery, comprised of 10 performance tests. Performance of the manganese-exposed workers was compared to that of a matched control group of 60 workers. Matching criteria were age, geographical area, type of work, and the results on a test of verbal comprehension. Performance of the exposed workers was inferior to that of the control group on tests of simple reaction time, digit span, and finger tapping. No correlations were found between performance and the present manganese exposure levels or the number of years employed in manganese work. The results seem to indicate that the present exposure standards for manganese, in Sweden 2.5 mg/m3 and in most other countries 5 mg/m3, are not sufficient to protect workers from negative effects on performance capacity.

CERN Document Server

A recurrent idea in the study of complex systems is that optimal information processing is to be found near bifurcation points or phase transitions. However, this heuristic hypothesis has few (if any) concrete realizations where a standard and biologically relevant quantity is optimized at criticality. Here we give a clear example of such a phenomenon: a network of excitable elements has its sensitivity and dynamic range maximized at the critical point of a non-equilibrium phase transition. Our results are compatible with the essential role of gap junctions in olfactory glomeruli and retinal ganglionar cell output. Synchronization and global oscillations also appear in the network dynamics. We propose that the main functional role of electrical coupling is to provide an enhancement of dynamic range, therefore allowing the coding of information spanning several orders of magnitude. The mechanism could provide a microscopic neural basis for psychophysical laws.

British Library Electronic Table of Contents (United Kingdom)

The offshore and inshore wave energy resource in Asturias (N Spain) is studied using wave buoy data and a hindcast dataset spanning 44 years (1958-2001). Offshore average wave power and annual wave energy values are found to exceed 30 kW/m and 250 MWh/m, respectively, at 7 of the 11 study sites. This substantial resource is characterised in terms of the sea states involved. Most of the energy is provided by IV quadrant waves with significant wave heights between 2 m and 5 m and energy periods between 11 s and 13 s. After analysing the offshore resource, numerical modelling is used to investigate the inshore wave patterns. A coastal wave model is validated with wave buoy data and applied to three case studies representative of storm, winter and summer conditions. Inshore wave energy concent...

British Library Electronic Table of Contents (United Kingdom)

Over 300 delegates participated in this scientific meeting to celebrate the career of the late Professor Tony Hart, who was Head of Department of Medical Microbiology, University of Liverpool, from 1986 until his death in September 2007. The meeting, which was opened by Professor James Stewart (Head, School of Infection and Host Defence, University of Liverpool) and closed by Professor Bernard Brabin (Head of the Child Health Group, Liverpool School of Tropical Medicine), captured some of the major elements that distinguished Tony Harts remarkable career. These included: broad research interests spanning both human and veterinary medicine; the ability to conduct both clinical and basic science research with equal skill and vigour; and his phenomenal mentorship of postgraduate students. Eac...

Energy Technology Data Exchange (ETDEWEB)

The findings reported in this study highlight several important features of the development of hematopoietic stem cells after transplantation into irradiated recipients. First, they demonstrate the existence of a class of primitive multipotential stem cells that can function for a significant portion of the lifetime of a mouse (15 mo). In addition, they clearly show that these primitive stem cells can be infected with recombinant retroviruses and thus would be appropriate targets for gene therapy in somatic tissues. Second, our data indicate that the progeny of some, but not all, of the primitive stem cells have fully expanded into the various hematopoietic lineages by 2 mo after reconstitution. Finally, our analysis of the secondary recipients provides strong evidence suggesting that the primitive stem cell population can actually clonally expand. Our current experiments are aimed at determining the extent to which this expansion can occur and whether or not this expansion can be ...

Energy Technology Data Exchange (ETDEWEB)

A 4.0 kb TaqI fragment of cosmid EFD64 isolated by a HBV-3 oligonucleotide was subcloned into AccI site of pUC18. MspI identifies 5 allelic VNTR polymorphism with bands between 2.6 and 4.6 kb. RsaI, TaqI, EcoRI, BamHI, HindIII and PvuII identify the same VNTR polymorphism. With RsaI, 80% heterozygosity were observed in 80 unrelated Caucasians. This RFLP pEFD64.2 has been assigned to chromosome 3 by linkage analysis with loci (APOD) known to span this chromosome. Co-dominant segregation for the RsaI RFLP was observed in 40 three generation families. RFLPs were observed under the normal hybridization and washing condition.

Energy Technology Data Exchange (ETDEWEB)

A model is presented to account for the effects of ion-induced defects during implantation processing of Si. It will be shown that processing is quite generally affected by the presence of defect excesses rather than the total number of defects. a defect is considered excess if it represents a surplus locally of one defect type over its compliment. Processing spanning a wide range of implantation conditions will be presented to demonstrate that the majority of the total defects played little or no role in the process. This is a direct result of the ease with which the spatially correlated Frenkel pairs recombine either dynamically or during a post-implantation annealing. Based upon this model, a method will be demonstrated for manipulating or engineering the excess defects to modify their effects. In particular high-energy, self-ions are shown to inject vacancies into a boron implanted region resulting in suppression of transient enhanced diffusion of the dopant.

Science.gov (United States)

The capacity to estimate the head pose of another person is a common human ability that presents a unique challenge for computer vision systems. Compared to face detection and recognition, which have been the primary foci of face-related vision research, identity-invariant head pose estimation has fewer rigorously evaluated systems or generic solutions. In this paper, we discuss the inherent difficulties in head pose estimation and present an organized survey describing the evolution of the field. Our discussion focuses on the advantages and disadvantages of each approach and spans 90 of the most innovative and characteristic papers that have been published on this topic. We compare these systems by focusing on their ability to estimate coarse and fine head pose, highlighting approaches that are well suited for unconstrained environments. PMID:19229078

International Nuclear Information System (INIS)

Measurements of the statistical characteristics of channel wall static pressure fluctuations in parallel one-component boiling flow are reported. The measurements span a wide range of local subcooling and vapor volume fraction, and correspond to flow regimes ranging from highly subcooled bubbly to saturated slug-annular. Vapor volume fraction measurements at the pressure measurement station are also reported in conjunction with visual observation of the flow structure. Variation of static pressure fluctuation intensity and spectral content with local thermal-hydraulic condition is demonstrated. Finally, it is suggested that diagnosis of local two-phase flow regime on the basis of (i) statistical characteristics of the pressure data, and (ii) time trace of pressure signal, may be possible. 15 refs.

International Nuclear Information System (INIS)

Paper presents conceptual design of free electron laser (FEL) complex for industrial applications. The FEL complex consists of three. FEL oscillators with the optical output spanning the infrared (IR) and ultraviolet (UV) wave-lengths (#lambda# = 0.3...20 #mu#m) and with the average output power 10 - 20 kW. The driving beam for the FELs is produced by a superconducting accelerator. The electron beam is transported to the FELs via three beam lines (125 MeV and 2 x 250 MeV). Peculiar feature of the proposed complex is a high efficiency of the. FEL oscillators, up to 20 %. This becomes possible due to the use of quasi-continuous electron beam and the use of the time-dependent undulator tapering.

International Nuclear Information System (INIS)

The stages of processes leading to radiation damage are studied, as well as, the direct and indirect mechanics of its production. The radiation effects on nucleic acid and protein macro moleculas are treated. The physical and chemical factors that modify radiosensibility are analysed, in particular the oxygen effects, the sensibilization by analogues of nitrogen bases, post-effects, chemical protection and inherent cell factors. Consideration is given to restoration processes by excision of injured fragments, the bloching of the excision restoration processes, the restoration of lesions caused by ionizing radiations and to the restoration by genetic recombination. Referring to somatic effects of radiation, the early ones and the acute syndrome of radiation are discussed. The difference of radiosensibility observed in mammalian cells and main observable alterations in tissues and organs are commented. Referring to delayed radiation effects, carcinogeneses, alterations of life ...

British Library Electronic Table of Contents (United Kingdom)

This manuscript is a contribution on the modeling of H.263 traffic in multipoint videoconference sessions over IP Networks. Our study includes analysis and modeling assessment of extensive data gathered during realistic videoconference sessions between commercial H.263-compliant terminal clients (with different videoconference software packages installed). All terminal clients were communicating through a Multipoint Control Unit (software or hardware MCU) at `switched presence' mode and for comparative purposes the same typical videoconference content (a person speaking, with mild movement and occasional zoom/span) was used. The analysis of the H.263 data at the frame level suggests that the traffic from the different terminals to the MCU can be represented by a stationary stochastic proce...

International Nuclear Information System (INIS)

The unique time scales associated with nuclear waste management require active work to preserve the knowledge associated with programs that can often span long time frames. For example, repository programs are designed and developed for the safe containment of radionuclides with half-lives on the order of 24,000 years (for Pu-239). Performance assessment studies are required to show, by predictive modeling, that these repositories can safely contain the waste for tens of thousands of years, with one million years a reality in the debate. Development of successful repository programs can span several decades. Once operational, a repository is expected to function until closure for a period of 30 to 40 years. Yet, the decision makers at all levels in such a repository program exert influence and authority over much shorter periods of time (e.g., four years for executive appointments). A discontinuous decision-making process and the associated ...

Science.gov (United States)

Blade fatigue life is an important element in determining the economic viability of the Vertical-Axis Wind Turbine (VAWT). A principal source of blade fatigue is thought to be the stochastic (i.e., random) aerodynamic loads created by atmospheric turbulence. This paper discusses the development of a model for the simulation of these stochastic loads, given the rotor geometry, operating conditions, and assumed turbulence properties. A Double-Multiple-Streamtube analysis is employed, which includes the effects of wind shear. Reynolds number variations, different airfoil sections and chord lengths along the blade span, and an empirical model for dynamic stall effects. Calculations are presented for the VAWT 34-m Test Bed currently being assembled at Bushland, Texas. Time histories of the loads, as well as their Fourier spectra, are presented and discussed. An unexpected finding is that the average output power is predicted to be more sensitive to turbulence level than ...

DEFF Research Database (Denmark)

Abstract This paper tries to investigate the problem of memory through one of its most intriguing patterns - chiasmus - reflected in old poetry, sacred texts, philosophy and theology, visual arts, as well as biology. It aims to search for some provisory explanation of why man was able once to acquire such excellence in memorizing internally thousands of lines of poetry, whereas now memory is expelled outside the human body and mind in a mere digital file. Contrasting the so-called "wish-dream for immortality" of the contemporary post-human body, this paper takes another path and looks into some old cosmologies and visions in which chiasmus constantly emerged as an enduring cultural paradigm with ontological relevance. Spanning from Plato to Christian theology, up to the contemporary Neo-Platonism of archetypal psychology, this paper hopes to put forth, if not a theory, at least a vision about man and cosmos, cosmos and man, a chiastic epiphany in which the body and ...

Science.gov (United States)

The relationship between hyperactivity and neuropsychological test performance at different age levels was examined. It was found that for young children (6 to 8 years of age, n = 90), there was no significant association between hyperactivity/attentional problems (as measured by the Hyperactivity scale of the Child Behavior Checklist) and performance on neuropsychological tasks thought to contain an attentional component (WISC-R Coding, Arithmetic, and Digit Span; WRAT Arithmetic; and the Benton Visual Retention Test). However, for older children (9 to 12 years of age, n = 92), there were significant and large negative correlations between CBC Hyperactivity scores and Coding, WRAT Arithmetic, and Benton VRT scores. Multiple regression analyses supported the above results (for Coding and WRAT Arithmetic), indicating that hyperactivity/inattention has a particularly deleterious effect on test performance (relative to same-age peers) as age increases. PMID:3361033

CERN Document Server

We examine star clusters in the irregular, starburst galaxy NGC 1569 from HST images. In addition to the two known super star clusters, we identify 45 other clusters that are compact but resolved. Integrated UVI colors of the clusters span a large range, and suggest that ages range from 3 Myrs to 1 Gyr. However, most of the clusters were formed at the tail end of the recent starburst. Numerous clusters in addition to the know super star clusters are similar in luminosity to a small globular cluster. We examined the radial surface brightness of four of the clusters. Their half-light radii and core radii are in the range observed in present-day globular clusters. Therefore, conditions that produced the recent starburst have also been those necessary for producing compact, bright star clusters. We examine resolved stars in the outer parts of the two super star clusters. Cluster A is dominated by bright blue stars with a small population of red supergiants. ...

Science.gov (United States)

We analyzed the effects of the Colorado Medicaid Capitation Program on the duration and services of over 21,000 outpatient mental health episodes for young children. The study spanned a three year period before and after capitation was implemented, and compared episodes of outpatient care for children from 14 capitated Community Mental Health Centers (CMHCs) with those from three CMHCs that remained fee-for-service. Proportional hazards regressions revealed that capitation resulted in an increase in outpatient episode duration, over and above similar effects for the comparison fee-for-service episodes. The hypothesis that there were longer capitated episodes for children who were hospitalized was not supported. Children with behavioral and anxiety disorders had longer capitated episodes. Service intensity decreased over time in the managed care sites. Changes in case mix may have had an impact on changes in episode duration and service intensity. That outpatient ...

Science.gov (United States)

Superconductivity of binary alloys spanning the A-15 compounds V/sub 3/Si, V/sub 3/Ge, V/sub 3/Ga, and V/sub 3/Al and the pseudobinary derivatives of these stoichiometric compounds was surveyed by studying samples prepared by rf-sputtering from alloy cathodes. The possible formation of the hypothetical A-15 binaries ''V/sub 3/P,'' ''V/sub 3/B,'' and ''V/sub 3/C'' and their pseudobinary formation with V/sub 3/Si was also explored. Efforts to form these hypothetical alloys were not successful. The T/sub c/'s were measured resistively and the structure and lattice constants were determined by x-ray analysis. A maximum T/sub c/ of 11.7/sup 0/K was obtained for A-15 V/sub 3/Al, and the importance of a suitable deposition temperature and high sputtering pressures was examined. It is proposed that large variations of T/sub c/ among pseudobinary alloys imply ...

CERN Document Server

This paper deals with the computation of sectional curvature for the manifolds of~$N$ landmarks (or feature points) in~$D$ dimensions, endowed with the Riemannian metric induced by the group action of diffeomorphisms. The inverse of the metric tensor for these manifolds (i.e.~the cometric), when written in coordinates, is such that each of its elements depends on at most~$2D$ of the~$ND$ coordinates. This makes the matrices of partial derivatives of the cometric very sparse in nature, thus suggesting solving the highly non-trivial problem of developing a formula that expresses sectional curvature in terms of the cometric and its first and second partial derivatives (we call this Mario's formula). We apply such formula to the manifolds of landmarks and in particular we fully explore the case of geodesics on which only two points have non-zero momenta and compute the sectional curvatures of 2-planes spanned by the tangents to such geodesics. The latter example gives ...

Science.gov (United States)

The Department of Defense (DoD) has long depended on military support functions enabled by space reconnaissance, surveillance, and target acquisition (RSTA) assets. Future generation satellite capabilities will further push technologies in space - if the right technologies are deployed in the right numbers and with the right payloads. Modeling and simulation play major parts in developing and deploying such assets: 1) system and operational requirements determination, and 2) assessment of military utility of such assets. Each area is critical in a system"s life cycle. Requirements determination cuts across the issues of doctrine, organizations, training, materiel, leader development, personnel, and facilities (DOTMLPF). Military utility assessments are necessary to explore and quantify the military worth/benefit of space RSTA assets to operational commanders. Each of these areas requires relevant modeling/simulation tools which span the engineering to system to ...

Science.gov (United States)

We have used a cell-free polymerase I transcription system derived from HeLa cells to study the regulation of human rRNA synthesis. Analysis of deletion mutants spanning the start site of transcription at nucleotide +1 indicates that the control region affecting initiation of human rRNA synthesis is contained within sequences from nucleotides -158 to +18. This promoter region can be subdivided into (i) a central segment of approximately 40 base pair that is required for transcription and (ii) flanking sequences that influence the efficiency of transcription in vitro. We have examined the in vitro transcriptional activity of the human extract under various conditions that are thought to modulate rRNA synthesis in vivo. Cell-free extracts prepared from HeLa cells infected with adenovirus 2 synthesize human rRNA at levels greatly decreased relative to uninfected cell extracts. By contrast, in vitro transcription of human rRNA is stimulated 2- to 3-fold by the addition ...

CERN Document Server

We examine patterns of variation of 32 primarily main sequence stars, extending our previous 7-12 year time series to 13-20 years by combining b, y data from Lowell Observatory with similar data from Fairborn Observatory. Parallel chromospheric Ca II H and K emission data from the Mount Wilson Observatory span the entire interval. The extended data strengthen the relationship between chromospheric and photometric variation derived previously. Twenty-seven stars are deemed variable. On a year-to-year timescale young active stars become fainter when their Ca II emission increases while older less active stars such as the Sun become brighter when their Ca II emission increases. The Sun's total irradiance variation, scaled to the b and y filter photometry, still appears to be somewhat smaller than stars in our limited sample with similar mean chromospheric activity, but we now regard this discrepancy as probably due mainly to our limited stellar sample

CERN Document Server

Let A and B be two affinely generating sets of (Z_2)^n. As usual, we denote their Minkowski sum by A+B. How small can A+B be, given the cardinalities of A and B? We give a fairly tight answer to this question. Our bound is attained when both A and B are unions of cosets of a certain subgroup of (Z_2)^n. These cosets are arranged as Hamming balls, the smaller of which has radius 1. By similar methods, we reprove the Freiman-Ruzsa theorem in (Z_2)^n, with an optimal upper bound. Denote by F(K) the maximal spanning constant || / |A|, over all subsets A of (Z_2)^n with doubling constant |A+A| / |A| < K. We explicitly calculate F(K), and in particular show that 4^K / 4K < F(K) (1+o(1)) < 4^K / 2K. This improves the estimate F(K) = poly(K) 4^K, found recently by Green and Tao and by Konyagin.

Energy Technology Data Exchange (ETDEWEB)

Pancreatitis-associated protein (PAP) is a secretory pancreatic protein present in small amounts in normal pancreas and overexpressed during the acute phase of pancreatitis. In this paper, the authors describe the cloning, characterization, and chromosomal mapping of the human PAP gene. The gene spans 2748 bp and contains six exons interrupted by five introns. The gene has a typical promoter containing the sequences TATAAA and CCAAT 28 and 52 bp upstream of the cap site, respectively. They found striking similarities in genomic organization as well as in the promoter sequences between the human and rat PAP genes. The human PAP gene was mapped to chromosome 2p12 using rodent-human hybrid cells and in situ chromosomal hybridization. This localization coincides with that of the reg/lithostathine gene, which encodes a pancreatic secretory protein structurally related to PAP, suggesting that both genes derived from the same ancestral gene by duplication. 35 refs., 4 ...

International Nuclear Information System (INIS)

Isomers have been populated in "2"4"6Cm and "2"5"2No with quantum numbers K"#pi#=8"-, which decay through K"#pi#=2"- rotational bands built on octupole vibrational states. For N=150 isotones with (even) atomic number Z=94-102, the K"#pi#=8"- and 2"- states have remarkably stable energies, indicating neutron excitations. An exception is a singular minimum in the 2"- energy at Z=98, due to the additional role of proton configurations. The nearly constant energies, in isotones spanning an 18% increase in Coulomb energy near the Coulomb limit, provide a test for theory. The two-quasiparticle K"#pi#=8"- energies are described with single-particle energies given by the Woods-Saxon potential and the K"#pi#=2"- vibrational energies by quasiparticle random-phase approximation calculations. Ramifications for self-consistent mean-field theory are discussed.

International Nuclear Information System (INIS)

Alloy 800 was developed in 1949 by The International Nickel Company, Inc. The basic composition, nominally 32wt.%Ni, 20.5wt.%Cr and 46wt.%Fe, was designed to provide a stable, fully austenitic structure and to impart high strength combined with resistance to oxidation, carburization and corrosion in a wide variety of aggressive industrial environments at elevated temperatures. In the short span of twenty-five years, alloy 800 has earned a unique position in the family of heat- and corrosion-resistant materials. Established uses include a wide range of applications in the industrial heating field, in the petro-chemical industry, in domestic appliances and in food processing equipment. The good performance of alloy 800 in these applications has led to its use as boiler tube material both in fossil-fired plants and in HTGR and PWR nuclear power systems. Recently, it was specified for a PHW CANDU reactor and it is now being considered as heat exchanger tube material ...

International Nuclear Information System (INIS)

Focused-ion beam (FIB) milling provides rapid fabrication of individual cylindrical submicrometer channels with reproducible dimensions (#+-#5% diameters) through 8-#mu#m thick poly(methylmethacrylate) (PMMA) films. PMMA films are spincast on sacrificial Si carriers and sputter-coated with Au before the 30-kV gallium FIB milling process. By adding a trace amount of poly(ethyleneoxide) and poly(dimethylsiloxane) to the PMMA solution before casting, the films can be released for subsequent mounting in microfluidic devices to create hybrid microfluidic-nanofluidic multilevel architectures. In situ FIB sectioning demonstrates the smooth cylindrical surface within the pore. Placing a milled film in contact with an aqueous fluorescein solution fills the channel by capillary action, as verified by confocal fluorescence microscopy. Confocal fluorescence of dyed films reveals that the pores span the thickness of the PMMA film. Small arrays of channels with a defined number ...

Environmental Research Database

Objectives7. (b) Objectives General background Livestock production accounts for 70% of the agricultural land on the planet. Given that demand for livestock products is expected to double by 2050 it is vital that we identify less polluting ways of production, spanning both intensive and extensive systems. Northern Europe is one of the few parts of the globe where climate change is expected to be neutral or even benefit agricultural productivity. Hence it is likely to make an even more important co [continued...]DescriptionRuminant genetic improvement can play an important role in developing livestock systems that will be sustainable in the future, and produce food in an environmentally friendly manner. Also, genetic improvement of livestock is a particularly cost-effective technology, producing permanent and cumulative changes in performance. Moran et al (2007) showed the very high value of animal and plant genetics research and development in helping to deliver on ...

International Nuclear Information System (INIS)

We report a detailed augmented-plane-wave energy-band study and wave-function analysis of stoichiometric PdH which shows that, even though the Fermi surface of PdH is qualitatively similar to that of silver, the simple ''proton model'' is not valid. Instead, the screening of the proton in PdH is found to be larger than in an isolated H atom due, in part, to the formation of a H-Pd bonding band below the bottom of the d-band complex. This result, which is in qualitative agreement with Switendick's earlier calculation, is confirmed by ultraviolet photoemission experiments. A partial density-of-states (DOS) analysis in the energy range spanned by the six valence and conduction bands reveals the quantitative details of the bonding mechanism between the Pd and H constituents. At the Fermi energy, the high Pd d to H s DOS ratio approx. 10.3 is found to be far higher than expected in silver, despite the fact that the Fermi-surface geometry is similar. The field-induced ...

International Nuclear Information System (INIS)

Beagle dogs given a single exposure to "2"3"9PuO_2 or "2"3"8PuO_2 aerosols are being observed for life-span dose-effect relationships. The "2"3"9Pu body burden of the nine dogs that died of pulmonary fibrosis-induced respiratory insufficiency during the first 3 yr after exposure was 1 to 12 #mu#Ci. One of these dogs had a pulmonary tumor. Five additional dogs with body burdens of 0.7 to 1.8 #mu#Ci died due to pulmonary neoplasia 3 to 5 yr after exposure. None of the dogs exposed to "2"3"8Pu have died during the first 3 postexposure yr. Lymphocytopenia was the earliest observed effect after inhalation of "2"3"9PuO_2 or "2"3"8PuO_2, occurring 0.5 to 2 yr after deposition of greater than or equal to 80 nCi plutonium in the lungs.

Energy Technology Data Exchange (ETDEWEB)

The current status of the ZTH vacuum liner design is covered by this report. ZTH will be the first experiment to be installed in the CPRF (Confinement Physics Research Facility) at the Los Alamos National Laboratory and is scheduled to be operational at the rated current of 4 MA in 1992. The vacuum vessel has a 2.4 m major radius and a 40 cm minor radius. Operating parameters which drive the vacuum vessel mechanical design include a 300 C bakeout temperature, an armour support system capable of withstanding 25 kV, a high toroidal resistance, 1250 kPa magnetic loading, a 10 minute cycle time, and high positional accuracy with respect to the conducting shell. The vacuum vessel design features which satisfy the operating parameters are defined. The liner is constructed of Inconel 625 and has a geometry which alternates sections of thin walled bellows with rigid ribs. These composite sections span between pairs of the 16 diagnostic stations to complete the torus. The ...

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Relativistic electron beams are used for generating high power microwaves. These microwave sources require electron beam generators spanning significant ranges in voltage and impedance. The pulsed power technology used to generate these electron beams is presented. Electron beam generators that produce beams with pulse durations in the 10 ns to 100 ns regime consist of an energy storage section, pulse shaping section, and an electron beam diode. The energy storage section is either a Marx generator or capacitor bank-pulsed transformer. The pulse shaping is done with high-voltage transmission lines. The electron beam diode is usually a cold-cathode, space-charge-limited flow device. For longer pulses (approx.1 ..mu..s) the energy storage and pulse shaping can be combined. Lumped-element pulsed-forming networks (PFN) can be designed to produce the desired pulse shape. The Marx generator becomes one of the elements of the PFN. Alternatively, a low voltage PFN followed ...

Energy Technology Data Exchange (ETDEWEB)

A phenomenological simulation was carried out for 41 experimental crystal-field (CF) levels within the {sup 4}I{sub 9/2-15/2}, {sup 4}F{sub 3/2-9/2}, {sup 4}S{sub 3/2} and {sup 2}H{sub 9/2} J manifolds, including the available infrared (IR) data up to {approx}15 000 cm{sup -1} for the Nd{sup 3+} ions in the Nd{sub 2}CuO{sub 4} single crystals. The CF Hamiltonian for the tetragonal C{sub 4v} symmetry was diagonalized together with the free-ion Hamiltonian in a basis that spans the entire 4f{sup 3} configuration. A rms error of 9 cm{sup -1} between the calculated and experimental energy level schemes was obtained. A comparison of the spectra in the visible region between the insulating Nd{sub 2}CuO{sub 4} and the metallic Nd{sub 2-x}Ce{sub x}CuO{sub 4}, allowed identifying the absorption bands associated with the development of the charge-doping induced local structural distortions in the superconducting regime.

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The reinforced concrete artificial iced course, constructed first in Japan as a bobsleigh and luge track for the Nagano Olympic Games, has a total extension of 1,700 m and an altitude difference of 113 m. It contains 15 curves and 2 up-grades and is divided into 43 blocks with spans ranging from 20 m to 80 m, all of which consist of lightwall RC members supported by pile foundations. The surface is cooled to -15 centigrade by the cooling pipes embedded in concrete and is iced by spraying water, and iced surface is shaved to make a course. Since the course scarcely has same profiles, the finished wall thickness is secured by fixing wire gauzes on the required positions without using shutterings. As there is not existed concrete satisfying all the required quality, two kinds of concrete were selected for filling in the arrangement of reinforcement and pipes and for surface finishing. Special notice was taken of the accuracy of finished surface. For the construction ...

International Nuclear Information System (INIS)

Following the publication (Stenhouse and Baxter, Nature; 267:828 (1977)) of the levels of bomb "1"4C and the residence times of carbon in the human body, excess radiation burdens from this radioisotope are evaluated under the assumption that no radiation dose, however small, can be regarded as entirely harmless biologically. The estimated annual absorbed dose attributable to "1"4C both natural and man-made for 1953-1973 and similar predicted figures for 1975-2025 are shown graphically. The cumulated doses to gonads (over 30 yr) and to bone marrow and bone-lining cells (over 60 yr) and also estimates of the biological damage to reproductive cells from "1"4C #beta#-irradiation (30 yr accumulated dose) are presented. It is concluded from both genetic and somatic considerations, that the potential human radiation burden due to artificially produced "1"4C calculated using the assumptions stated is certainly significant and, therefore, cannot be dismissed. However, relative to the world ...

International Nuclear Information System (INIS)

The authors describe the application of an approximate fuzzy C-means (AFCM) clustering algorithm as a data dimension reduction approach to medical magnetic resonance images (MRI). Image data consisted of one T1-weighted, two T2-weighted, and one T2*-weighted (magnetic susceptibility) image for each cranial study and a matrix of 10 images generated from 10 combinations of TE and TR for each body lymphoma study. All images were obtained with a 1.5 Tesla imaging system (GE Signa). Analyses were performed on over 100 MR image sets with a variety of pathologies. The cluster analysis was operated in an unsupervised mode and computational overhead was minimized by utilizing a table look-up approach without adversely affecting accuracy. Image data were first segmented into 2 coarse clusters, each of which was then subdivided into 16 fine clusters. The final tissue classifications were presented as color-coded anatomically-mapped images and as two and three dimensional displays of cluster ...

International Nuclear Information System (INIS)

Youngkwang Unit 3,4 and Ulchin Unit 3 and 4 have had problem of the KSNP Steam Generator due to a severe fretting wear on the tube. In particular, the wears were localized and concentrated in the upper part of U-bend of the Central Cavity region. At the upper tube bundle Central Cavity, the fluid flow velocities and void fraction are very high, because the steam is made by high heat transfer at secondary region. Also, this region is affected easily by fretting wear due to it's unsupported span is longer than another regions. The fretting wear is assumed to be result of Flow-Induced Vibration (F. I. V), which can occur by many mechanisms. EFDP was added to UCN 5,6 for prevent fretting wear by the SEC LCC and DSHIC, a company of design and manufacture of the steam generator, respectively. In order to evaluate the efficacy of EFDP, ANSYS and ATHOS-3 Code were used. From sensitivity analysis and calculation results, Density and Velocity into the Central Cavity are ...

Energy Technology Data Exchange (ETDEWEB)

This disclosure provides a solar rechargeable aircraft that is inexpensive to produce, is steerable, and can remain airborne almost indefinitely. The preferred aircraft is a span-loaded flying wing, having no fuselage or rudder. Travelling at relatively slow speeds, and having a two-hundred foot wingspan that mounts photovoltaic cells on most all of the wing`s top surface, the aircraft uses only differential thrust of its eight propellers to turn. Each of five sections of the wing has one or more engines and photovoltaic arrays, and produces its own lift independent of the other sections, to avoid loading them. Five two-sided photovoltaic arrays, in all, are mounted on the wing, and receive photovoltaic energy both incident on top of the wing, and which is incident also from below, through a bottom, transparent surface. The aircraft is capable of a top speed of about ninety miles per hour, which enables the aircraft to attain and can continuously maintain altitudes ...

CERN Document Server

This paper reports on the detection of optical novae in our neighbour galaxy M31 based on digitized historical Tautenburg Schmidt plates. The accurate positions of the detected novae lead to a much larger database for searches for recurrent novae in M31. We conducted a systematic search for novae on 306 digitized Tautenburg Schmidt plates covering a time span of 36 years from 1960 to 1996. From the database of both ~ 300 000 light curves and about one million detections on only one plate per colour band, nova candidates were efficiently selected by automated algorithms and subsequently individually inspected by eye. We report the detection of 84 nova candidates. In detail we found 55 nova candidates from the automated analysis of the light curves. Among these, 22 were previously unknown, 12 were known but have not been identified on Tautenburg Schmidt plates before and 21 novae have been discovered on Tautenburg plates previously. An additional 29 known novae could ...

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To reconstruct the profiles of heavy metal levels in the South Ocean ecosystem of Antarctica, the concentrations of lead (Pb), copper (Cu), arsenic (As), cadmium (Cd), and zinc (Zn) in seal hairs and lake sediments spanning the past 1500 years from Fildes Peninsula of King George Island and in weathering lake sediments from Nelson Island of West Antarctica were determined. The lead contents in the seal hairs and the weathering sediments show a sharp increase since the late 1800s, very likely due to anthropogenic contamination from modern industries. After the 1980s, the Pb content in seal hairs dropped by one-third, apparently due to the reduced usage of leaded gasoline in the Southern Hemisphere. Copper arises mainly from the weathering process, and its level may be substantially affected by climatic conditions. The concentrations of Cd, As, and Zn do not show any clear temporal trends.

Energy Technology Data Exchange (ETDEWEB)

Overhead persistent surveillance systems are becoming more capable at acquiring wide-field image sequences for long time-spans. The need to exploit this data is becoming ever greater. The ability to track a single vehicle of interest or to track all the observable vehicles, which may number in the thousands, over large, cluttered regions while they persist in the imagery is very desirable. Typically, this imagery has many thousands of pixels on a side and is characterized by lower resolutions (e.g. {approx}0.5 meters/pixel to {approx}2.0 meters/pixel) and lower frame rates (e.g. {approx} sub-Hz to several Hz). We describe our ultra-scale capable implementation of a multiple-vehicle tracking algorithm for overhead persistent surveillance imagery. This work builds upon an earlier report, where now the algorithm has been modified for improved performance and has been substantially improved to handle much larger datasets in a much shorter time.

International Nuclear Information System (INIS)

Delayed neutron energy spectra have been measured for six delay-time intervals following the fast fission of "2"3"8U nuclei. The delay-time intervals span the range 0.17 to 10.2 seconds following initial fission while the measured spectra span neutron energies from 10 keV to 4 MeV. The experiment was performed utilizing the UMass/Lowell 5.5 MV Van de Graff accelerator to produce fast neutrons for inducing fission in a "2"3"8U lined fission chamber. The fission fragments were flushed via a helium jet stream to a well-shielded counting room where they were deposited onto a moving tape (magnetic audio tape) and transferred to a beta-neutron time-of-flight spectrometer. By adjusting the tape speed, composite delayed neutron time-of-flight spectra were measured for several different delay-time intervals. These measurements involved beta-neutron coincidences with "6Li-loaded glass scintillators for neutron energies from 10 keV to 450 keV and Bicron ...

Science.gov (United States)

The twin-cities of El Paso and Juarez share the water resources of the Hueco Bolson aquifer and overlying Rio Grande aquifer. Both aquifers span the international border between Mexico and the United States. Salinity in the Rio Grande aquifer varies widely, some parts of the shallow aquifer containing less than 1,000 mg/L total dissolved solids (TDS), other parts of the aquifer exceeding 5,000 mg/L TDS. One sizable part of the "Lower Valley" area, approximately 45 km below El Paso contains very dilute water near the outer edge of the floodplain. Historically it had been thought that the dilute waters in this location were derived from recharge from arroyos that drained proximal parts of the Hueco Bolson. Instead, our hydrogen and oxygen isotope data and carbon-14 data indicate that these dilute waters were derived from pre-dam infiltration of the Rio Grande. Relatively light and slightly evaporated pre-dam waters (-11.5 del O18) at the arroyos are also ...

International Nuclear Information System (INIS)

The objectives of this research were (1) to analyze the transfers of 137Cs and 60Co in a retention pond, with emphasis on aquatic insects and (2) to determine if detectable concentrations of these radionuclides are exported by emerging aquatic insects. We analyzed the radionuclide concentrations in the following components: water solution, bottom sediments, suspended particulate matter, plankton, floating mats of filamentous algae, benthic macroinvertebrates, and emerging aquatic insects. Samples were collected quarterly from June 1981 to April 1982. The lowest concentrations (in picocuries per milliliter) occurred in solution (range: 1.4 X 10(2) to 3.2 X 10(2) for 137Cs and 8.1 X 10(-1) to 2.2 X 10(0) for 60Co). The highest concentrations (in picocuries per gram dry weight) occurred in the sediments (range: 1.5 X 10(4) to 1.1 X 10(8) for 137Cs and 1.0 X 10(2) to 4.3 X 10(6) for 60Co). The primary producers and aquatic insect consumers had concentrations of both radionuclides that were ...

Energy Technology Data Exchange (ETDEWEB)

The Plant Life Assessment Network (PLAN) is a Brite Euram Type II Thematic Network, initiated by the European Commission to facilitate structured co-operation between all cost shared action projects already funded by the Commission which fall under this common technical theme. The projects involved address a multiplicity of problems associated with plant life assessment and are drawn from Brite-Euram, Standards, Measurement and Testing, Nuclear Fission Safety and Esprit EC programmes. The main aim of the Network is to initiate, maintain and monitor a fruitful co-operation process between completed, ongoing and future EC R and D projects, thereby promoting improved cross fertilization and enhanced industrial exploitation of R and D results. As the project is in its infancy, this presentation covers the background to the initiative in some detail. In particular two key aspects are highlighted, namely, the requirement of the EC to launch such a network in the area of plant life assessment ...

International Nuclear Information System (INIS)

We study the relation between size and star formation activity in a complete sample of 225 massive (M_* > 5 x 10"1"0 M _s_u_n) galaxies at 1.5 < z < 2.5, selected from the FIREWORKS UV-IR catalog of the CDFS. Based on stellar population synthesis model fits to the observed rest-frame UV-NIR spectral energy distributions, and independent MIPS 24 #mu#m observations, 65% of the galaxies are actively forming stars, while 35% are quiescent. Using sizes derived from two-dimensional surface brightness profile fits to high-resolution (FWHM_P_S_F #approx# 0.''45) ground-based ISAAC data, we confirm and improve the significance of the relation between star formation activity and compactness found in previous studies, using a large, complete mass-limited sample. At z #approx# 2, massive quiescent galaxies are significantly smaller than massive star-forming galaxies, and a median factor of 0.34 #+-# 0.02 smaller than galaxies of similar mass in the local universe. Thirteen percent of the ...

International Nuclear Information System (INIS)

The symmetrical complexes ["9"9"mTc][TcN(R_2PS_2)_2] [R = CH_3, CH_2CH_3, CH_2CH_2CH_3, CH_2(CH_3)_2], and the unsymmetrical complex ["9"9"mTc][TcN(Me_2PS_2)(Et_2PS_2)] have been prepared, at tracer level, through a two-step procedure involving the preliminary formation of a prereduced technetium nitrido intermediate followed by substitution reaction onto this species by the appropriate dithiophosphinate ligand [R_2PS_2]Na. The chemical identity of the resulting complexes have been established by comparison with the corresponding "9"9Tc-analogs prepared, at macroscopic level, by reacting the complex ["9"9TcNCl_4] [n-Bu_4N] (n-Bu = n-butyl) with an excess of ligand in methanol, and characterized by elemental analyses and spectroscopic techniques. The complexes are neutral and lipophilic, and possess a square pyramidal geometry, with an apical Tc N group and two dithiophosphinate ligands spanning the four positions on the basal plane through the four sulfur atoms of ...

Energy Technology Data Exchange (ETDEWEB)

Research over a three year time span involved the study of multiphase flow useful to understanding the scaleup of coal liquefaction reactors. We attempted to establish the flow patterns and their boundaries in which a direct coal liquefaction, large diameter, bubble column operates. A flow map has been proposed in which coal slurry properties can be input to determine the flow pattern boundaries at reactor operating conditions. Gas holdup and bubble diameters have been measured under different conditions of gas and liquid flow rate. These have been used to determine interfacial area in bubble columns. An equation for the estimation of interfacial area in the bubble-slug flow pattern has been proposed. It has also been established that gas holdup and thus interfacial area depends strongly on the gas distribution in the column. Porous plate gas distributors can yield gas holdups twice as large as sieve plate distributors. Measurements using aqueous solutions (carboxy ...

Energy Technology Data Exchange (ETDEWEB)

The centromere is the most characteristic landmark of eukaryotic chromosomes. Centromeres function as the site for kinetochore assembly and spindle attachment, allowing for the faithful pairing and segregation of sister chromatids during cell division. Characterization of centromeric DNA is not only essential to understand the structure and organization of plant genomes, but it is also a critical step in the development of plant artificial chromosomes. The centromeres of most model eukaryotic species, consist predominantly of long arrays of satellite DNA. Determining the precise DNA boundary of a centromere has proven to be a difficult task in multicellular eukaryotes. We have successfully cloned and sequenced the centromere of rice chromosome 8 (Cen8), representing the first fully sequenced centromere from any multicellular eukaryotes. The functional core of Cen8 spans ~800 kb of DNA, which was determined by chromatin immunoprecipitation (ChIP) using an antibody ...

International Nuclear Information System (INIS)

Tumor-targeted monoclonal antibodies (mAb) might be useful as diagnostic or therapeutic agents when linked to cytotoxic or imaging reagents. Our group is working to test this hypothesis by linking cytocidal and image-producing isotopes to mAb and testing the utility of the radioimmunoconjugates formed in animal model systems. Radioiodines were first employed for these purposes,but unfavorable nuclear properties (half-lives, #gamma#-ray and #beta#-particle energies) and chemical reactivity (deiodination in vivo) limit their utility. Labeling immunoproteins with metallic radionuclides offers more versatility in that the selection of potentially useful radiometals spans the periodic table.Of the metallic radionuclides with physical properties most suited for use with mAb in nuclear medicine, few are more available or desirable than those of bismuth ("2"1"2Bi) and lead ("2"0"3Pb, "2"1"2Pb), as listed in Table 1. "2"1"2Bi or "2"1"2Pb could serve as sources for highly ...

International Nuclear Information System (INIS)

An on-going inter-comparison programme which is focused on assessing and establishing consensus protocols to be applied in the identification, selection and sub-sampling of materials for subsequent "1"4C analysis is described. The outcome of the programme will provide a detailed quantification of the uncertainties associated with "1"4C measurements including the issues of accuracy and precision. Such projects have become recognised as a fundamental aspect of continuing laboratory quality assurance schemes, providing a mechanism for the harmonisation of measurements and for demonstrating the traceability of results. The design of this study and its rationale are described. In summary, a suite of core samples has been defined which will be made available to both AMS and radiometric laboratories. These core materials are representative of routinely dated material and their ages span the full range of the applied "1"4C time-scale. Two of the samples are of wood from ...

Energy Technology Data Exchange (ETDEWEB)

Manganese is an essential metal of toxicologic concern primarily because of exposure via inhalation. Environmental forms of Mn exist mainly as insoluble oxides, yet much of the research information available relates to the soluble salts. In the present study, adult male Sprague-Dawley rats were intratracheally instilled with either soluble MnCl/sub 2/ or insoluble Mn/sub 3/O/sub 4/ labeled with /sup 54/Mn. Lungs and other major organs were sampled over a span of 3 mo after dosing with the respective chemicals, which were equivalent to 8 ..mu..Ci and 1 ..mu..mol of manganese in 0.2 ml of buffer. There was rapid clearance of Mn from the lungs in the case of both chemicals; the chloride cleared at an initial rate of nearly four times that of the oxide. Despite this early difference, the amount of /sup 54/Mn remaining in the lungs after 2 wk was similar for both compounds. The level of /sup 54/Mn in the liver, kidney, spleen, and testes peaked at the 3-d sampling point ...

International Nuclear Information System (INIS)

The purpose of this paper is to evaluate a complete set of environmental pathways for disposal options and conditions that the Nuclear Regulatory Commission (NRC) may analyze for a low-level radioactive waste (LLW) license application. The regulations pertaining In the past, shallow-land burial has been used for the disposal of low-level radioactive waste. However, with the advent of the State Compact system of LLW disposal, many alternative technologies may be used. The alternative LLW disposal facilities include below- ground vault, tumulus, above-ground vault, shaft, and mine disposal This paper will form the foundation of an update of the previously developed Sandia National Laboratories (SNL)/NRC LLW performance assessment methodology. Based on the pathway assessment for alternative disposal methods, a determination will be made about whether the current methodology can satisfactorily analyze the pathways and phenomena likely to be important for the full range of potential ...

Energy Technology Data Exchange (ETDEWEB)

Blade fatigue life is an important element in determining the economic viability of the Vertical-Axis Wind Turbine (VAWT). A principal source of blade fatigue is thought to be the stochastic (i.e., random) aerodynamic loads created by atmospheric turbulence. This report describes the theoretical background of the VAWT Stochastic Aerodynamic Loads (VAWT-SAL) computer code, whose purpose is to numerically simulate these random loads, given the rotor geometry, operating conditions, and assumed turbulence properties. A Double-Multiple-Stream Tube (DMST) analysis is employed to model the rotor's aerodynamic response. The analysis includes the effects of Reynolds number variations, different airfoil sections and chord lengths along the blade span, and an empirical model for dynamic stall effects. The mean ambient wind is assumed to have a shear profile which is described by either a power law or a logarithmic variation with height above ground. Superimposed on ...

Energy Technology Data Exchange (ETDEWEB)

Laron syndrome (LS) is an autosomal recessively inherited condition characterized by insensitivity to endogenous and exogenous GH. Affected individuals have severe episodes and other characteristic features. GH receptor gene mutations are present in all affected individuals in whom molecular studies have been reported. The GH receptor is a plasma membrane-spanning protein in which the extracellular domain binds circulating GH and the intracellular domain interacts with the JAK-2 kinase and possibly other intracellular signaling molecules. GH receptor dimerization occurs on GH binding and is thought to be required for normal signal transduction. We have studied the GH receptor genes of four unrelated individuals affected with LS from the United States, Italy, Saudi Arabia, and India. We have identified four different missense mutations that alter consecutive amino acids 152 to 155 in or near the dimerization domain of the GH receptor. One of these mutations, D152H, ...

Energy Technology Data Exchange (ETDEWEB)

This paper describes the development, design, and fabrication of the crude oil process facilities, and the conversion of an existing tanker for use at the Liuhua 11-1 Field. Over a 16-month period spanning 1994 and 1995, Amoco Orient Petroleum Company, and partners, China Offshore Oil Nanhai East Corporation (CONHE), and Kerr-McGee China Petroleum Ltd., converted a crude oil tanker originally built in 1975 to the Nanhai Sheng Li, the floating production, storage and offloading (FPSO) facility for the Liuhua 11-1 Field. The FPSO will process up to 65,000 BOPD produced from 20 subsea wells located 1.7 miles away. In addition to the processing facilities for produced oil and water, the FPSO has a processed crude oil storage capacity of 715,000 bbls. The ship`s propulsion system was removed during the conversion, because the FPSO is permanently moored at site by means of a 10-point, ``soft`` mooring. The mooring system was designed to survive the 100-year-return-period ...

Energy Technology Data Exchange (ETDEWEB)

This document is the Final Report for the project. Improvements in SISCOM II Technology. It consists of a brief description of the activities carried out during the project, and several Annexes that explain in a deeper way each result. SISCOM II is the main telemetry system currently in use in the Spanish underground coal mining, but it was developed ten years ago and needed a technological update, which was the objective of this project. The aims of the project were: - To develop Hardware and Software for the Outstations currently used (maintenance developments) - To design new hardware and software, easier to use in the current and new applications of SISCOM II Both objectives were met, although not in the way originally intended. The main results were: In the field of old Outstations update: - A new set of boards for the old Outstations was developed - Outstations`s firmware was updated for the new hardware In the field new hardware and software design: - SISCOM II Supervision ...

Energy Technology Data Exchange (ETDEWEB)

This paper describes a Honshu-Shikoku linking transmission cable building plan and its technical features. The Chugoku District and the Shikoku District are supplied with power currently by the Chugoku-Shikoku trunk line of 220,000 volts. To cope with the anticipated power shortage, a plan was established to install power cables for 500,000 volts on the Honshu-Shikoku connecting bridge. The plan calls far an installation length of 127.4 km and a transmission capacity of 1.2 million kW per line. The cable installation on the Seto Bridge was completed already, the construction is now in the peak period for building steel towers on the land sections, and laying overhead cables and underground cables. Commencement of the operation is scheduled 1994 on one liner, and 2000 on two lines. The technical features include the Japan's first large-capacity, long-distance underground transmission cable installation, and the installation of the multi-conductor overhead cables having ...

Energy Technology Data Exchange (ETDEWEB)

Experiments on heat transfer augmentation in a rectangular cross-section water channel are reported. The channel geometry is designed to excite normally damped Tollmein-Schlichting modes in order to enhance mixing. In this experiment, a hydrodynamically fully developed flow encounters a test section where one channel boundary is a series of periodic, saw-tooth, transverse grooves. Free shear layers span the groove openings, separating the main channel flow from the circulating vortices contained within each cavity. The periodicity length of the grooves is equal to one-half of the expected wavelength of the most unstable mode. The remaining channel walls are flat, and the channel has an aspect ratio of 10:1. Experiments are performed over the Reynolds number range of 300 to 15,000. Streakline flow visualization shows that the flow is steady at the entrance, but becomes oscillatory downstream of an onset location. This location moves upstream with increasing Reynolds ...

International Nuclear Information System (INIS)

The response of the reactive flow detector (RFD) toward organometallic compounds of several transition metals has been explored, and several of its strong elemental responses have been characterized in detail. The RFDs minimum detectable flow (measured in picograms of metal per second at S/N_p_-_t_-_p=2) is 0.1 for ruthenium, 3 for chromium, 10 for manganese, 5 for nickel, 15 for iron, and 2 for osmium. Typically, the linearity of response spans four orders of magnitude, with atomic selectivity of metal versus carbon ranging from 2 to 3 orders. Response quenching by co-eluting hydrocarbons is not observed. As a demonstration experiment, the common analysis of methylcyclopentadienyl manganese tricarbonyl (MMT) in gasoline is carried out on an RFD system modified for dual-channel operation. The results show that dual-channel operation of the RFD can increase the native elemental selectivity of manganese over carbon by a factor of 100, in accordance with earlier ...

International Nuclear Information System (INIS)

"1"4C measurement uses a number of standards and reference materials with different properties. Historically the absolute calibration of "1"4C measurement was tied to 1890 wood, through the 'primary' standard of NBS-OxI (produced by the National Bureau of Standards, now NIST - National Institute of Standards and technology) subsequently replaced by NBS-OxII. These are both internationally calibrated and certified materials, whose "1"4C activities are known absolutely. A second tier of materials, often called secondary standards or reference materials, and including internationally recognised materials such as ANU-sucrose (now also IAEA-C6), Chinese - sucrose and the IAEA C1-C6 series, augmented by additional oxalic acid samples are also used routinely. The activity of these materials has been estimated from large numbers of measurements made by many laboratories. Recently, further natural materials from the Third and Fourth International Radiocarbon Inter-comparisons (TIRI and FIRI) ...

Science.gov (United States)

Based on a recent investigation that modeled the elastic properties (ie, strength, stiffness and range) of multistranded wires made from linearly elastic materials, three-stranded (triple) and six-stranded coaxial (coax) stainless steel (SS) wires were compared to single-stranded (single) SS and conventional nickel titanium (NiTi) leveling wires. To measure Young's modulus of elasticity (E), flexural tests were performed with an Instron mechanical testing machine in a three-point bending arrangement having a span length of 8.9 mm or 12.5 mm. A strong correlation between wire stiffness and the area moment of inertia demonstrated that strand interaction was negligible at low activations and that E = 199 GPa was constant even for the heavily drawn coax strands. Using the Instron with an extensometer, the 0.1% yield strengths (sigma(YS)) of the single SS wires and the straight inner strands within the coax wires were tested. The ratio of the sigma(YS) to the ultimate ...

International Nuclear Information System (INIS)

Full text of publication follows: The effect of neutron irradiation on the thermal conductivity of silicon carbide can be dramatic depending on the irradiation temperature and fluence the material is subjected to, and may be a critical factor defining it's use in fusion systems. Historically there have been several papers describing the effect of neutron irradiation on thermal conductivity degradation of SiC, predominately in the low to intermediate temperature ranges. Practically all of this work has been at temperatures lower than the application temperature for SiC being considered by the conceptual fusion reactors. This paper provides new data on the thermal conductivity of high quality CVD silicon carbide irradiated in a range of doses and temperature spanning the proposed fusion reactor temperature range. Specifically, an irradiation was carried out from fractions milli-dpa to approximately 8 dpa in the HFIR with irradiation temperatures ranging from 80-1600 ...

Energy Technology Data Exchange (ETDEWEB)

In the present study Balb/c mice were exposed to 3,4-benzopyrene, painted on the skin every 2nd day for a total of 6 months, and simultaneously irradiated with athermal (5 mW/cm/sup 2/) or subthermal (15 mW/cm/sup 2/) doses of 2,450 MHz microwaves. The other group of animals was preirradiated with microwaves at 10 mW/cm/sup 2/ power level for 1, 2, or 3 months and then treated with benzopyrene, as above. Control mice were exposed for 6 months to benzopyrene, resulting in the development of baso- or spinocellular skin carcinoma within approximately 9 months, and sham-irradiated with microwaves. The growth of the tumour was assessed according to a self-designed 7-range macroscopic scale, supported by microscopical examinations of skin sections. All protocols of microwave irradiations resulted in a significant acceleration of the development of benzopyrene-induced skin cancer and in shortening of life span of the tumour-bearing hosts. This effect seemed to be ...

Energy Technology Data Exchange (ETDEWEB)

A variety of surveillance operations require the ability to track vehicles over a long period of time using sequences of images taken from a camera mounted on an airborne or similar platform. In order to be able to see and track a vehicle for any length of time, either a persistent surveillance imager is needed that can image wide fields of view over a long time-span or a highly maneuverable smaller field-of-view imager is needed that can follow the vehicle of interest. The algorithm described here was designed for the persistence surveillance case. In turns out that most vehicle tracking algorithms described in the literature[1,2,3,4] are designed for higher frame rates (> 5 FPS) and relatively short ground sampling distances (GSD) and resolutions ({approx} few cm to a couple tens of cm). But for our datasets, we are restricted to lower resolutions and GSD's ({ge}0.5 m) and limited frame-rates ({le}2.0 Hz). As a consequence, we designed our own ...

Energy Technology Data Exchange (ETDEWEB)

Southeastern Finland belongs to the area covered by the Weichselian ice sheet, where the release of the ice load caused a rapid isostatic rebound during the postglacial time. While the mean overall apparent uplift is of the order of 2 mm/yr today, in the early Holocene time it was several times higher. A marked decrease in the rebound rate occurred around 8500 BP, however, since then the uplift rate has remained high until today, with a slightly decreasing trend towards the present time. According to current understanding there have neither been temporary increases nor decreases in the rate of uplift during the postglacial time. Even so, it is not known for sure whether there are regional irregularities on the rebound in Finland. Concurrently with land uplift, relative sea-level changes in the Baltic basin were also strongly affected by the global eustatic rise of sea-level. During the early Litorina Sea stage on the southern coast of Finland around 7000 BP, the rise in sea-level ...

International Nuclear Information System (INIS)

We study the origin and properties of 'extra' or 'excess' central light in the surface brightness profiles of cusp or power-law elliptical galaxies. Dissipational mergers give rise to two-component profiles: an outer profile established by violent relaxation acting on stars already present in the progenitor galaxies prior to the final stages of the merger, and an inner stellar population comprising the extra light, formed in a compact central starburst. By combining a large set of hydrodynamical simulations with data that span a broad range of profiles at various masses, we show that observed cusp ellipticals appear consistent with the predicted 'extra light' structure, and we use our simulations to motivate a two-component description of the observations that allows us to examine how the properties and mass of this component scale with, e.g., the mass, gas content, and other properties of the galaxies. We show how to robustly separate the physically meaningful ...

Energy Technology Data Exchange (ETDEWEB)

Maintenance of power stations so far operated on the concept of using or extending the expected service life of a machine or plant as far as possible in order to avoid early and costly replacement. This was done by means of time-oriented maintenance, inspection and repair, otherwise called preventive maintenance. A European study on maintenance methods totals the cost of these measures at between 140 to 200 billion DM. One way of reducing these costs is 'predictive maintenance'. Estimated savings are about 8 percent or between 12 and 16 billion DM per year. Predictive maintenance identifies irregulaties of machine parts at an early point in time by means of condition monitoring and can help to cut costs: unplanned repairs can be avoided; repairs can be fitted into production schedules; production will not be disturbed to to unforeseen repairs, optimised spare part warehousing helps to cut costs. Predictive maintenance aims at keeping availability high, give maximum ...

Energy Technology Data Exchange (ETDEWEB)

The existence of problems with wild pigs (Sus scrofa) is nothing new to the Western Hemisphere. Damage by these introduced animals was reported as far back as 1505 by the early Spanish colonies in the Caribbean, where wild pigs were killing the colonists cattle. Droves of these animals also ravaged cultivated crops of maize and sugarcane on islands in the West Indies during this same time period. These wild pigs reportedly were very aggressive and often attacked Spanish soldiers hunting rebellious Indians or escaped slaves on these islands, especially when these animals were cornered. The documentation of such impacts by introduced populations of this species in the United States has subsequently increased in recent years, and continued up through the present (Towne and Wentworth. 1950, Wood and Barrett 1979, Mayer and Brisbin 1991, Dickson et al. 2001). In spite of a fairly constant history in this country since the early 1900s, wild pigs have had a dramatic recent increase in both ...

Energy Technology Data Exchange (ETDEWEB)

Low energy buildings promise significant energy savings and help climate preservation by cutting down on annual heating requirements to values below 70 kWh per m{sup 2} dwelling space. It is expected that low energy constructions will become the common standard by the year 2000 as a result of the forthcoming energy saving ordinance. For making the introduction and implementation of this standard successful, practical experience will be essential. For this reason, the state government of Hesse has supported respective pilot projects 1987. In 1989 the funding programme `30 low energy buildings in Hesse` has been established. Consecutively - between 1989 and 1993 - 29 buildings were erected. At first, the thermal quality of the crafted building construction including the ventilation systems was checked. Consecutively, energy consumption, indoor and outdoor temperatures were measured over a time span of several years. The experience of the inhabitants was surveyed. The ...