Full text: Research reactors have been playing a multi dimensional role in areas of nuclear fuel cycle programme, radio-isotope productions, neutron beam research etc. To ensure an efficient, smooth and safe operation of a nuclear research reactor, many reactor physics evaluations are required on routine basis. As part of reactor core management the important activities are maintaining core reactivity status, core power distribution, xenon estimations, safety evaluation of in-pile irradiation samples and experimental assemblies and assessment of nuclear safety in fuel handling/storage. In-pile irradiation requires a prior estimation of the reactivity load due to the sample, heating rate and the activity developed in it during irradiation. For the safety of the personnel handling irradiated samples the dose rate at the surface of shielded flask housing the irradiated sample should be less than 200 mR/Hr. Therefore, a proper shielding and ...
Research performed at LAMPF during 1985 is reported in the areas of: nuclear and particle physics; atomic and molecular physics; materials science; radiation-effects studies; biomedical research and instrumentation; nuclear chemistry; radioisotope production; and physics theory. Also reported are the status of LAMPF-II, facility development work, and accelerator operations. (LEW)
Results are reported from studies of the diffusion rate of xenon through frog abdominal skin and toad urinary bladders, typical epithelial membranes. It was concluded that intracellular water serves as the principal barrier for xenon passage through epithelial tissue.
As radiation detection in the interest of national security becomes increasingly commonplace, inevitable questions arise concerning the interpretation of data from handheld radioisotope identifiers (RIIDs). Field elements typically require fast answers to provide an effective defense and to minimize the impact on legitimate movement of people and goods. To support this need, on-call experts at Sandia, Los Alamos, and Lawrence Livermore national laboratories cooperate in resolving radiation alarms rapidly and accurately. We present an overview, describe the work in progress to improve capabilities, and report on some of the lessons learned.
Scintillation light in liquid xenon excited by 100 MeV/n Al ions was detected with a home-made silicon photodiode. The diameter of the photodiode was 2 inch. The effective quantum efficiency was observed to be 22% for the wavelength of liquid xenon scintillation light (170 nm), while the effective quantum efficiency for 5.486 MeV alpha-particle excitation was 44%. An energy resolution of 0.5% rms was achieved for the energy deposition of 2.5 GeV in liquid xenon using a fast preamplifier ({approx equal} 20 ns). (orig.).
Femoral head replacement was performed for femoral neck fracture or femoral head necrosis on 36 hips of 34 patients on whom Tc-99m MDP scintigraphy was done for analysis of radioisotope uptake around the prosthesis. In the cases with satisfactory clinical course after replacement surgery the uptake was high in the area between the prosthesis and the trochanter, in the area of the stem tip of the prosthesis and in the acetabular area. The high uptake decreased gradually and reached a normal level by 8 months after surgery. The cases with no decrease of high uptake by 8 months after surgery were considered to have had an eventful postoperative course associated with some complication such as infection, fracture, loosening etc. Tc-99m MDP scintigraphy was useful for early detection of complications and to evaluate progress of the operated patients. (author)
During FY1997, the JMTR was operated for 3 complete cycles (120th, 121st and 122nd cycles) and was utilized for the research and development programs on the technology of LWRs and fusion reactor, as well as for fundamental research of fuels and materials, and for radioisotope productions. The improvement of evaluation technique in a local neutron spectrum for irradiation utilization and development of capsule having the vertical migration, the reinstrumentation and loading mechanism have been carried out. Development of a new oxygen potential sensor for oxide fuel pellets has been done as an elemental technology of irradiation for high burn-up fuels. As for post irradiation examination, the techniques for measuring of crack length using an alternating current potential drop method and machining of miniaturized specimen by the remote handling have been developed. A research on the blanket materials and components for thermonuclear fusion reactor were also ...
Researches and production of radio-isotopes, radio-pharmaceuticals and cold kits are carried out in the Radio-isotope Production Facility (RIPF). Four concrete hot cells in Bank-1 are to produce the Ir-192 source for NDT. Eleven lead hot cells in Bank-2 are to produce Ho-166, Cr-51, P-32/33, Tc-99m, Lu-177, Sr-90/Y-90 and W-188/Re-188 for research purpose. Six lead hot cells in Bank-3 are used for the production of I-131 for diagnosis and therapy of cancer in the hospital. A hot cell in Bank-3 is also utilized for the research of I-125 and Br-82. Four lead hot cells in Bank-4 are utilized for the production of Mo-99/Tc-99m generators since 2005. The major systems including the Heat and Ventilated Air Conditioning (HVAC) system and the air cleaning system such as charcoal and HEPA filter trains to filter the radioactive contaminants are in operation. So are the systems such as power supply and distribution system, UPS, fire protection system, ...
The fission gas xenon bonded in bubbles, in pore, and in the lattice of mixed carbide fuels is measured by electron-probe microanalysis. Radial xenon distribution and release curves are determined and are calibrated by gas chromatography of the bonded fission gas and by burnup analysis in the respective pin sections of the irradiation experiments FR2 6A and 6C, Mol 11/K 2, and DFR 330/1. The results are correlated to the microstructure of the fuel, bonding medium, temperature, and burnup. (Auth.).
High pressure xenon ionization chamber detectors are possible alternatives to traditional thallium doped sodium iodide (NaI(Tl)) and hyperpure germanium as gamma spectrometers in certain applications. Xenon detectors incorporating a Frisch grid exhibit energy resolutions comparable to cadmium/zinc/telluride (CZT) (e.g. 2% (at) 662keV) but with far greater sensitive volumes. The Frisch grid reduces the position dependence of the anode pulse risetimes, but it also increases the detector vibration sensitivity, anode capacitance, voltage requirements and mechanical complexity. We have been investigating the possibility of eliminating the grid electrode in high-pressure xenon detectors and preserving the high energy resolution using electronic risetime compensation methods. A two-electrode cylindrical high pressure xenon gamma detector coupled to time-to-amplitude conversion electronics was used to ...
RADIANT{trademark} is manufactured by United States Surgical Corporation, Vascular Therapies Division, (formerly Progressive Angioplasty Systems). The system comprises a liquid {beta}-radiation source, a shielded isolation/transfer device (ISAT), modified over-the-wire or rapid exchange delivery balloons, and accessory kits. The liquid {beta}-source is Rhenium-188 in the form of sodium perrhenate (NaReO{sub 4}), Rhenium-188 is primarily a {beta}-emitter with a physical half-life of 17.0 hours. The maximum energy of the {beta}-particles is 2.1 MeV. The source is produced daily in the nuclear pharmacy hot lab by eluting a Tungsten-188/Rhenium-188 generator manufactured by Oak Ridge National Laboratory (ORNL). Using anion exchange columns and Millipore filters the effluent is concentrated to approximately 100 mCi/ml, calibrated, and loaded into the (ISAT) which is subsequently transported to the cardiac catheterization laboratory. The delivery catheters are modified ...
We have studied the nature of continuum emitted in the visible spectral range from a noncontracted positive column of discharge in a cesium vapor-xenon mixture at a pressure of 45 Torr and at a degree of ionization below 3 ? 10?6. The main contribution to the continuous emission under such conditions is due to electron-xenon atom bremsstrahlung. The intensity of emission has been experimentally and theoretically studied as a function of the electric field strength and electron density in the positive column. It is established that an increase in the visible emission intensity with the electric field strength is related to an increase in the number of hot electrons in plasma.
A noninvasive method is described for estimating local cerebral blood flow (LCBF) and local partition coefficients by means of computed tomographic scanning during inhalation of 30% stable xenon gas in oxygen. Time-dependent xenon concentrations in arterial blood and brain tissue during the wash-in and washout phases are used to calculate partition coefficients and LCBF values by means of a least-squares curve-fitting analysis. Control values for partition coefficient and LCBF obtained from control subjects with minor head trauma in the chronic stage were compatible with those in several past reports, and reproducibility was satisfactory. The theoretic grounds underlying this new method of curve-fitting analysis are discussed.
A noninvasive method is described for estimating local cerebral blood flow (LCBF) and local partition coefficients by means of computed tomographic scanning during inhalation of 30% stable xenon gas in oxygen. Time-dependent xenon concentrations in arterial blood and brain tissue during the wash-in and washout phases are used to calculate partition coefficients and LCBF values by means of a least-squares curve-fitting analysis. Control values for partition coefficient and LCBF obtained from control subjects with minor head trauma in the chronic stage were compatible with those in several past reports, and reproducibility was satisfactory. The theoretic grounds underlying this new method of curve-fitting analysis are discussed.
Carrier-free "8"8Y radioisotope, which has the longest half life (T=106.6 d) of yttrium radioisotopes and is a #gamma#-ray emitter, was obtained by proton irradiation of strontium, followed by cooling for one month. Then, "8"8Y was purified by precipitating strontium as strontium nitrate and extracting yttrium with tri-n-butyl phosphate (TBP). The decontamination factor of strontium to yttrium was more than 4x10"3 and chemically pure yttrium radioisotope was obtained. (author) 6 refs.
This study mainly concerns medical explorations by radioisotopes. Detectors with medical exams and applications are described. Ionisation chambers, semiconductor detectors and scintillation counters are also presented. Uses of radioisotopes in medicine in vivo and in vitro techniques are explained. Examples of scintiscanning are given like: angiography, nuclear cardiography and thyroid scintiscanning. The importance of the study is to present a panorama of nuclear medicine laboratories -at the time- in hospitals in Lebanon.
All the tests have been finished up in the Waste Management and Disposal Facility which has been used for the safety tests of solidified radioactive waste on sea dumping disposal. The decommissioning of this facility was performed for use of radioisotopes. This report describes the plan on decommissioning of facility for use of radioisotopes, the contamination checking methods and measurement of radioactivity, the fore case and practice for amount of generated radioactive wastes, the operation procedures for dismantlement, the safety measures, the expenses for decommissioning and so on. (author)
The pure xenon dc positive column discharge has been characterized for various xenon pressures, currents, and discharge tube radii. The absolute output at the 147 nm resonance transition has been measured using two independent techniques to yield the radiant emittance at 147 nm (power per unit surface area). The efficiency of 147 nm production is obtained by combining the measured radiant emittance with the measured electrical power per unit length deposited in the gas. The radiant emittance and the efficiency are the two principle figures of merit for characterizing the discharge as a source of VUV radiation. It is observed that the trends in efficiency and radiant emittance change substantially when the discharge transitions from two-step electron impact excitation/ionization at higher pressures to single-step electron impact ionization at lower pressures. Modeling of the xenon positive column discharge yields radiant ...
A brief comparative review of possible mercury free fluorescent lighting technologies is presented, including rare-gas positive column discharges, molecular discharges, and dielectric barrier discharges. Detailed experimental results on xenon positive column discharges will then be considered. In order to judge whether xenon-based discharges are a viable UV source it is necessary to measure the radiant emittance (power per unit area) for the vacuum ultraviolet (VUV) resonance xenon emission at 147 nm. Two techniques to determine the VUV radiant emittance have been developed and applied to xenon discharges. One method combines the measured resonance level density using absorption spectroscopy and a calculation of the trapped decay rate for the resonance radiation to arrive at the radiant emittance at 147 nm. A second method utilizes a direct measurement of the radiance (power per unit area per unit solid ...
In this paper the availability and properties of radioisotopes for both radioimmunodiagnosis (RAID) and radioimmunotherapy (RAIT) are discussed. Examples are provided for radioisotopes available via direct production in nuclear reactors and accelerators or as daughters obtained from radionuclide generator systems whose parents are either reactor or accelerator produced. Important factors which must be considered for the use of a particular radioisotope include availability, the physical half-life and decay properties, and chemical versatility for protein attachment. Although both direct'' and indirect'' methods are available for attachment of radioisotopes to antibodies, this broad field of research is not reviewed in detail. Practical issues related to the availability and use of a variety of radionuclides are described. 47 refs., 5 tabs.
The production methods for seven radioisotopes, Ga-67, Sr-85, Pd-103, In-111, Tu-167, Hg-197 and Pb-203, by using a classical 1.5m cyclotron in the Institute of Physics and Power Engineering, Obninsk, USSR, are described. At present, more than 50 cyclotrons in different countries are used for the production of radioisotopes applied to medicine. Radioisotopes are produced with the cyclotron in the I.Ph.P.E. in the form of irradiated targets, which are delivered to Moscow radiopharmaceutical factory, where radiopharmaceuticals are produced on the base of these targets. The cyclotron is operated in two regimes providing the acceleration of protons, deuterons and alpha -particles. Two types of target assemblies are used for irradiation, the one is intended for the internal beam, and the other is for the external beam. The reactions used for the production of seven radioisotopes described above, the types of ...
The production methods for seven radioisotopes, Ga-67, Sr-85, Pd-103, In-111, Tm-167, Hg-197 and Pb-203, by using a classical 1.5m cyclotron in the Institute of Physics and Power Engineering, Obninsk, USSR, are described. At present, more than 50 cyclotrons in different countries are used for the production of radioisotopes applied to medicine. Radioisotopes are produced with the cyclotron in the I.Ph.P.E. in the form of irradiated targets, which are delivered to Moscow radiopharmaceutical factory, where radiopharmaceuticals are produced on the base of these targets. The cyclotron is operated in two regimes providing the acceleration of protons, deuterons and alpha -particles. Two types of target assemblies are used for irradiation, the one is intended for the internal beam, and the other is for the external beam. The reactions used for the production of seven radioisotopes described above, the types of ...
Analytical procedures are described for the determination of organic compounds, metals and radioisotopes in environmental materials, human tissues, urine, feces, and waste water.
Although the radioisotope liver scan has primarily been of use in the detection of the intra-hepatic space occupying lesions, there has been an increasing awareness of its use in evaluation of liver function. In this study, the degree of hepatomegaly, changes in shape and mottling radiodensity on each lobe and splenic visualization in the liver scans done with colloidal radiogold were numerically expressed as scores under the arbitrary standard in 210 patients with liver cirrhosis. The clinical value of this scoring system was studied with special regards to the correlation between the radiogold hepatic uptake half time and conventional liver function tests. Following were the results; 1) The normal scan appeared in 6.7% of 210 patients with liver cirrhosis. 2) The colloidal radiogold hepatic uptake half time was abnormally and progressively prolonged in parallel to severity of hepatocellular dysfunction. The mean hepatic uptake half time in ...
In order to judge the potential fluorescent lamp applications of various low-pressure positive column discharges it is necessary to measure the absolute power emitted in the ultraviolet region of the spectrum. For rare-gas discharges the principle emission occurs in the vacuum ultraviolet so that it is difficult to measure the radiant emittance (power per unit area) of the resonance radiation by standard methods. Two independent techniques are discussed for measuring the radiant emittance of positive column discharges in the vacuum ultraviolet. These techniques are used to study xenon positive column discharges at the resonance wavelength of 147 nm. The first method relies on the measurement of the resonance level density by absorption techniques. The effective decay rate of the resonance level is then determined by the simulation of resonance radiation transport. These two quantities are combined to yield the radiant emittance at 147 nm without implementing vacuum ...
Monitoring for xenon radionuclides which are produced in a nuclear detonation can provide a strong deterrent to the violation of a Comprehensive nuclear Test Ban Treaty (CTBT). There are 18 known radioactive xenon isotopes produced in nuclear fission with half-lives ranging from less than one second to 11.9 days. However, only four of these remain in significant amounts more than a day after a detonation. In order for radioxenon monitoring to be practical, it was necessary to develop an automated measurement system which could operate unattended for periods of months, measure the entire spectrum of radioxenons, and provide hundreds of times better sensitivities than current laboratory procedures. This capability was developed at the US Department of Energy`s Pacific Northwest National Laboratory based on rapid separation of atmospheric xenon coupled with a unique high sensitivity measurement device for the radioxenons. A ...
Measurement results of total interaction cross sections averaged by the spectrum of ultracold neutrons (UCN) within the rate range from 3.2 to 5.7 m/s at the temperatures of 80 and 300 K for the following gases: hydrogen, parahydrogen, helium-4, nitrogen, neon, argon, xenon are presented. The experiment has been conducted conducted in the facility for UCN extraction, mounted in the radial channel of the WWR-K reactor. Experimental dependences of UCN counting rate on pressure of the investigated gases in the chamber varying from 0 to 1.5x10/sup 3/ torr are presented graphically. The measured total cross sections mainly satisfactorily agree with calculations, divergences are observed only for hydrogen and xenon.
Based on a collisional-radiative model, an atomic-kinetic calculation of the gains on the 41.8-nm transitions of Pd-like xenon was performed for the plasma produced due to the interaction of a femtosecond laser pulse with gaseous xenon. The gains g(z,{tau}) averaged over the spatial and temporal coordinates were compared with the known gains which had been measured experimentally in Xe{sup 8+}. The amplification was shown to occur under the conditions of ionisation of the working ions, and the time of output radiation saturation depends on the time of Xe{sup 8+} transformation to higher-ionised ions. Our theoretical investigation enables determining the optimal pump parameters, at which the product of the gain g by the active medium length L is about 20, which exceeds the experimental gL value. (active media)
Based on a collisional-radiative model, an atomic-kinetic calculation of the gains on the 41.8-nm transitions of Pd-like xenon was performed for the plasma produced due to the interaction of a femtosecond laser pulse with gaseous xenon. The gains g(z,?) averaged over the spatial and temporal coordinates were compared with the known gains which had been measured experimentally in Xe8+. The amplification was shown to occur under the conditions of ionisation of the working ions, and the time of output radiation saturation depends on the time of Xe8+ transformation to higher-ionised ions. Our theoretical investigation enables determining the optimal pump parameters, at which the product of the gain g by the active medium length L is about 20, which exceeds the experimental gL value. (active media)
We have observed EUV spectra from the Large Helical Device (LHD) at the National Institute for Fusion Science (NIFS). We measured spectra of impurity ions; carbon, iron, xenon, tin and tungsten ions. In some cases, the plasma evolution was stable and a steady discharge was obtained, but sometimes the plasma underwent radiation collapse and rapid cooling. For carbon and iron spectra, we studied plasma diagnostics by intensity ratios of spectral lines. For other spectra of higher Z element, xenon, tin and tungsten, we studied mainly on line identifications comparing with theoretical calculations and experimental data. Related atomic data for these researches will be also discussed. (author)
Two geriatic male rhesus monkeys were used for the radioisotope imaging in this research. Discussion of the radionuclide, materials, and method used to accomplish the neurologic examination and the results obtained, both during the procedure and confirmation of the results by necropsies were accompanied by color photos of scan images. Results were that the nuclear images provided accurate images of intracranial neoplasia.
NASA and DOE plan a cooperative team effort with industry, government laboratories and universities to develop a near term, low cost, low power (100 watt electric class), low mass (<10 kg), advanced radioisotope space power source (ARPS) and in the process reduce the plutonium-related costs as well. The near term is focused on developing an advanced energy converter to use with the General Purpose Heat Source (GPHS). The GPHS was developed and used for the current radioisotope thermoelectric generators (RTGs). Advanced energy converter technologies are needed as a more efficient replacement for the existing thermoelectric converters so that the space radioisotope power source mass and cost can be reduced. a more advanced technology space radioisotope power system program is also planned that addresses a longer-term need. Twenty first century robotic scientific information missions to the outer ...
A procedure for the determination of lead in soil samples by "2"0"3Pb radioisotope dilution substoichiometric method is described. Japan NIES No.2 river clay standard sample and 83-40 Tibet soil standard sample were determined. The obtained values were in good agreement with reference values. The standard deviation of the method was less then 5%. Detection limit was about 0.1 #mu#g Pb.
The Rayleigh scattering length has been calculated for rare-gas liquids in the ultraviolet for the frequencies at which they luminesce. The calculations are based on the measured dielectric constants in the gas phase, except in the case of xenon for which measurements are available in the liquid. The scattering length mayplace constraints on the design of some large-scale detectors, using uv luminescence, being proposed to observe solar neutrinos and dark matter. Rayleigh scattering in mixtures of rare-gas mixtures is also discussed.
An embodiment of a mercury-free fluorescent lamp combines a low pressure rare gas discharges with a phosphor having a quantum efficiency grater than one. The choice of the rare gas depends on a number of factors, one of which is the resonance transition energy. Less demand is placed the quantum efficiency of the phosphor for a lower energy resonance photon. Xenon has the lowest energy resonance transition of the stable rare gases at 8.5 eV (147 nm) and thus is a good candidate to study. The usefulness of a xenon-based discharge depends on the radiant emittance of the discharge at the resonance wavelength of 147 nm. The radiant emittance from a low pressure xenon positive column discharge is measured using two independent techniques. The first relies on the measurement of the resonance level density using absorption techniques. The effective decay rate of the resonance level is calculated using radiation trapping theory. The ...
The Comprehensive Nuclear-Test-Ban-Treaty (CTBT), which was opened for signature in 1996, bans all nuclear explosions in all environments. Republic of Korea has been working to monitor compliance with CTBT by deterring and detecting any nuclear explosions conducted anywhere on Earth. For the verification of CTBT, several techniques are implemented. Radionuclide monitoring is of particular importance since it is the only method which can provide absolute assurance that a nuclear detonation has occurred
A krypton recovery pilot plant has been completed for the Power Reactor and Nuclear Fuel Development Corporation. This is the first industrial facility in the world to make practical use of development results for offgas treatment and storage from nuclear facilities. The cryogenic distillation process was adopted as a proven and reliable method to separate krypton and xenon, and to reduce gas effuents to a level so low that the decontamination factor amounts to more than 1000.
This paper describes a method for preparing the sample handling and inlet system of a mass spectrometer for analysis of a subsequent sample following analysis of a previous sample comprising the flushing of the system interior with supercritical CO{sub 2} and venting the interior. The method eliminates the effect of system ``memory`` on the subsequent analysis, especially following persistent samples such as xenon and krypton.
The radioisotope production facilities and programs of the 86-Inch Cyclotron are reviewed in this presentation. The 86-Inch Cyclotron is designed to accelerate protons to a maximum energy of 22 MeV for internal targets. These protons are used to bombard metals that are electroplated, potted or soldered to water-cooled plates. Additionally, metals and inorganic compounds are bombarded in water-cooled tube targets. High radioisotope production rates are obtained by beam currents as large as 3 mA. Production rates for /sup 11/C, /sup 57/Co, /sup 67/Ga, /sup 68/Ge, /sup 109/Cd, and other isotopes are presented. The production of /sup 11/C for the carboxyl labeling of amino acids in cooperation with Oak Ridge Associated Universities is discussed. The 86-Inch Cyclotron is used for those programs requiring a larger beam current than is available from commercial cyclotrons.
Processes and apparatus are disclosed for generation of radioisotope contaminant fission fragment free ozone from oxygen containing streams by chemonuclear irradiation accomplished by passing the stream past high energy radiation sources placed in sealed chambers.
We present a software system that computationally reproduces biochemical radioisotope-tracer experiments. It consists of three main components: A mapping database of substrate-product atomic correspondents...Full Text Available
Radioisotope facilities were operated to support research, development and production of radioisotopes. Irradiation facilities were operated to offer irradiation service to the clients. Even though intensive periodical checks and some essential maintenance had been carried out the results of RI facility maintenance seemed to be not much satisfactory due mainly to the shortage of skilled manpower and maintenance expenses. High intensity {gamma} irradiator was normally operated 426 times for overall 3,440 hrs, and the low intensity {gamma} irradiator was operated 157 times for overall 11,092 hrs, respectively. (author)
A simple highly efficient procedure has been developed for recovery of thallium radioisotopes from lead and bismuth targets irradiated by 1-GeV protons. The procedure is based on the use of extraction chromatography. The cross-sections have been determined for formation of {sup 200}Pb, {sup 201}Pb, {sup 202m}Pb, and {sup 203}Pb radioisotopes in targets from lead with natural isotopic composition, irradiated by 1-GeV protons.
A simple highly efficient procedure has been developed for recovery of thallium radioisotopes from lead and bismuth targets irradiated by 1-GeV protons. The procedure is based on the use of extraction chromatography. The cross-sections have been determined for formation of "2"0"0Pb, "2"0"1Pb, "2"0"2"mPb, and "2"0"3Pb radioisotopes in targets from lead with natural isotopic composition, irradiated by 1-GeV protons.
Formulae are derived for estimation of the effect of gamma beam divergence on the value of systematic and statistical components of the errors of density measurement in production of structural materials and products also in the process of exploitation of building structures and constructions. Engineering technique for choice of the distance between radiation source and object under test is developed for absorption radioisotope densimeter operating by the scheme of geometry of divergent beam with amplitude compensation of backscattered radiation effect. The assessment of radioisotope densimeter efficiency providing the error of density measurement prescribed at design stage
The availability of reactor-produced radioisotopes in the United States for use in medical research and nuclear medicine has traditionally depended on facilities which are an integral part of the US national laboratories and a few reactors at universities. One exception is the reactor in Sterling Forest, New York, originally operated as part of the Cintichem (Union Carbide) system, which is currently in the process of permanent shutdown. Since there are no industry-run reactors in the US, the national laboratories and universities thus play a critical role in providing reactor-produced radioisotopes for medical research and clinical use. The goal of this survey is to provide a comprehensive summary of these production capabilities. With the temporary shutdown of the Oak Ridge National Laboratory (ORNL) High Flux Isotope Reactor (HFIR) in November 1986, the radioisotopes required for DOE-supported radionuclide generators ...
We studied regional myocardial perfusion by scintigraphic computer-assisted analysis of initial distribution, washout rates, and residual activity of "1"3"3Xe injected into the left coronary artery of four patients with normal arteriograms and 14 patients with coronary stenosis. At rest, residual activity in poststenotic regions was always greater than in control regions, but initial washout rates were not slower. During angina, following xenon injections, the amount of indicator distributed to the poststenotic regions was markedly reduced; the increase of the initial washout rates was smaller than in control regions relative to rest, and residual activity was higher. Initial washout rates did not differ as much as from those of normal myocardium because in severe ischemia too little indicator is deposited initially in these regions to produce a change of any magnitude. Indeed, when angina was induced immediately after the xenon injection, ...
Non-invasive methods are described for estimating local cerebal blood flows (LCBF) and local partition coefficients (Llambda) during inhalation of 30 % stable xenon gas (Xe) in oxygen during CT scanning. After the denitrogenation with pure oxygen breathing, 30 % Xe is inhaled for four minutes to minimize subanesthetic effects with a rubber facemask and the delivery system of Xe. Local time-..delta.. Hounsfield units curve during the Xe wash-in and wash-out phase is utilized in order to calculate Llambda and LCBF using a least squares curve fitting analysis. Calculated Llambda and LCBF with the new method manifested reasonable distribution between the grey and white matters, and reproducibility was excellent in our study. Several case studies of patients with cerebral infarction are presented to demonstrate the characterization of Llambda and LCBF patterns in various tissues and theoretical grounds underlying the new method of curve fitting analysis are discussed.
Non-invasive methods are described for estimating local cerebal blood flows (LCBF) and local partition coefficients (L#lambda#) during inhalation of 30 % stable xenon gas (Xe) in oxygen during CT scanning. After the denitrogenation with pure oxygen breathing, 30 % Xe is inhaled for four minutes to minimize subanesthetic effects with a rubber facemask and the delivery system of Xe. Local time-#DELTA# Hounsfield units curve during the Xe wash-in and wash-out phase is utilized in order to calculate L#lambda# and LCBF using a least squares curve fitting analysis. Calculated L#lambda# and LCBF with the new method manifested reasonable distribution between the grey and white matters, and reproducibility was excellent in our study. Several case studies of patients with cerebral infarction are presented to demonstrate the characterization of L#lambda# and LCBF patterns in various tissues and theoretical grounds underlying the new method of curve fitting analysis are ...
Cesium recovery from the polluted layers in the 1/3 scale hydrogen negative ion source for LHD-NBI system has tested. It was found, that the cesium recovery can be produced by additional discharges as from the cesium layer, aged by tungsten and residual gas, so as from the cesium layers, polluted by an occasional water leak. The highest cesium recovery to NI production was produced by a xenon arc, while glow discharge and arcing in hydrogen were less effective. The mechanism of recovery is the ejection of cesium from the underlying enriched layer by the arc and its transport to the surface. (author)
The purpose of this work was to develop and evaluate a method of locating breached fuel within the Fast Flux Test Facility (FFTF) reactor based on the relative response of the delayed neutron monitors (DNM) located on each of the three primary sodium cooling loops. The primary method of location is the use of tag gas containing unique ratios of the noble gases xenon and krypton. Although the tag gas system works quite well, it is relatively expensive because of the costs of preparing and loading the gas into each fuel pin. Triangulation of DNM signals could potentially decrease tag gas costs while maintaining overall location reliability.
Many monitoring activities require the collection of whole air samples over an extended time interval without loss or concentration of any atmospheric constituents. Described is the development and laboratory testing of a whole air sampler capable of collecting a 100 liter sample over a period of 0.63 days. The sampler has an empty weight of 7.79 kg and an overall size of 20.8-cm {times} 20.8-cm {times} 66.1-cm. The conceptual design for the development of smaller, higher-performance whole air samplers is also reported.
Characteristics of lead-zirconate-titanate (PZT) elements were studied by directly irradiating them with a 400 MeV/n Xe beam. The elements were sensitive to 10{sup 4} Xe ions and their output amplitudes were proportional to the beam intensity. An ensemble of those output amplitudes displayed a Bragg-curve-like response towards the range of 400 MeV/n Xe ion. We discuss the potential of PZT elements as a radiation detector and their application to high-intensity and high-energy detectors. (author)
A computer code based on Nodal expansion method has been developed for solving two groups three dimensional diffusion equation. This code can be used for fuel management and time average core calculation. Explicit Xenon and fuel temperature estimation are also incorporated in this code. TAPP-4 phase-B physics experimental results were analyzed using this code and a code based on FD method. This paper gives the comparison of the observed data and the results obtained with this code and FD code. (author)
In Pressurised heavy water reactors (PHWRs), neutron poison in the moderator is used to compensate the excess reactivity present in the core on different occasions such as xenon decay during synchronization just after poison out period or start ups from xenon free conditions. It is also used in secondary shutdown system (SDS-2), where required amount of neutron poison is injected directly into the moderator within 2.5 seconds. Further, it is also used for over poisoning the moderator to achieve the guaranteed shutdown state when the regular shutdown systems are taken for maintenance. Generally, two types of moderator poisons are used in power reactors to balance the reactivity of the core and they are boron and gadolinium. Gadolinium is used in the form of gadolinium nitrate (Gd(NO3)3.6H2O). The paper gives the details of estimation of reactivity coefficients of gadolinium for 540 MWe PHWR for different operating conditions. These neutron ...
A mission to the surface of Venus would have high scientific value, but most electronic devices and sensors cannot operate at the 450degreeC ambient surface temperature of Venus. Power and cooling systems were analyzed for Venus surface operation. A radioisotope power and cooling system was designed to provide electrical power for a probe operating on the surface of Venus. For a mission duration of substantial length, the use of thermal mass to maintain an operable temperature range is likely impractical, and active refrigeration may be required to keep components at a temperature below ambient. Due to the high thermal convection of the high-density atmosphere, the heat rejection temperature was assumed to be at a 500degreeC radiator temperature, 50degreeC above ambient. The radioisotope S...
This paper reviews the state of the art of silicon-germanium technology and assesses the problems of building thermoelectric modules in Europe, based upon silicon-germanium alloys, for use in multihundred watt radio-isotope thermoelectric generator. The generator developed in the United States for the International Solar Polar mission has been used as a reference system. The essential features of an alternative system, which employs thermocouples fabricated from improved silicon-germanium alloys based upon a design by the Fairchild Space and Electronics Company, is also described. It is concluded that although the fabrication of reliable electrical contacts will present a major problem, the technology is available in Europe to build thermoelectric modules similar to those developed for the International Solar Polar mission. (orig.).
In the Carpathian Basin, significant percentage of watershed area and floodplains of rivers are utilised agriculturally. Several potential sources of poisonous metal pollution have been identified in these areas. Because of spills from some of them a few severe accidents have happened especially in the watershed area of Tisza River during the last decades. The motivation of our present work was to produce {sup 62,65}Zn and {sup 203}Pb radioisotopes because they can be used especially as tracers for studying the kinetics of uptake, transport and accumulation of zinc and lead by plants under different circumstances. (orig.)
In the Carpathian Basin, significant percentage of watershed area and floodplains of rivers are utilised agriculturally. Several potential sources of poisonous metal pollution have been identified in these areas. Because of spills from some of them a few severe accidents have happened especially in the watershed area of Tisza River during the last decades. The motivation of our present work was to produce "6"2","6"5Zn and "2"0"3Pb radioisotopes because they can be used especially as tracers for studying the kinetics of uptake, transport and accumulation of zinc and lead by plants under different circumstances. (orig.)
Nuclear battery produces electricity by converting radiation energy into electrical energy. Energy carried by particles emitted by a radioisotope nuclei is much higher than that released in chemical reaction. Reaction with nuclei can potentially produce electricity thousand to million times higher than that of chemical reaction. Unlike NPP that produces large scale alternating current using thermodynamic cycle such as Rankine or Brayton cycles, nuclear battery is designed like other battery or fuel cell, to produce direct current (DC). However, both battery utilize the energy or particles radiating from nuclei of a radioisotope. In this paper, several types of nuclear battery as an energy converter are discussed, including their working mechanisms and examples. Nuclear battery is potential to become a long-life power source for use in wide range of applications, including in medical areas and for instruments in remote areas and outer space.
A newly-available radioisotopic system, /sup 172/Hf-/sup 172/Lu, has excellent potential for tracer applications in which nuclear data acquisition must be accomplished in real time. The 6.7-day half-life of /sup 172/Lu is sufficient for a large fraction of tracer experiments, and should allow the direct incorporation of /sup 172/Lu into tests that have traditionally utilized much longer-lived radionuclides. Since /sup 172/Lu is the daughter component of a radioisotope generator, however, its effective shelf-life is determined by the half-life of its 1.9-year /sup 172/Hf parent. Consequently, the frequency of isotope procurement need not be any more extensive than investigators would normally be accustomed to. Discussion relevant to isotope production, generator operation, and nuclide acquisition is presented in this paper.
Summaries are included of research contracts which expired prior to Dec. 31, 1960. The contracts were concerned with investigations of: electrophysiological responses of biological systems in nerve cells to irradiation with small doses of ionizing radiations; the mode of the protective action of certain sulfhydryl compounds against radiation effects on the synthesis of deoxyribonucleic acid, using tritium-labeled thymidine; development of a bubble chamber method of monitoring and dosimetry for Low fast neutron fluxes; effects of incorporated radioisotopes on the stability of genetic materials; interrelation of root and leaf absorption of radioisotopes in herbaceous plants; uptake of radioactive wastes by lowland rice from soils contaminated by irrigation water, and decontamination of the rice; and comparison between mutation rates induced by acute and chronic gamma irradiations. (B.O.G.)
Ovine and caprine lentiviruses share the capacity to induce slowly progressive and inflammatory diseases of the central nervous system (leukoencephalitis or visna), lungs (progressive pneumonia or maedi),...Full Text Available
AIM: This paper reviews progression in renal diseases. METHODS: An English language literature search using Medline (1980 January-2001 July) was done to assess research and review articles on progression...Full Text Available
This issue is the collection of the papers on progress of researches by common utilization of JAERI nuclear facilities. The 43 of the papers are indexed individually. (J.P.N.)
BackgroundHealth service databases of administrative type can be a useful tool for the study of progression of a disease, but the data reported in such sources could be affected...Full Text Available
Improving patient compliance with physicians’ treatment or prescription recommendations is an important goal in medical practice. We examine the relationship between treatment progress...Full Text Available
BackgroundLymphangioleiomyomatosis (LAM) is a rare lung disease characterised by progressive airflow obstruction. No effective medical treatment is available but therapy with sirolimus...Full Text Available
A computer was built for use with the NRU reactor to solve the problem of Xe/sup 135/ concentrations. The effect of any changes in reactor on Xe/sup 135/ concentration can be predicted and steps taken to avoid poisoning out. An electromechanical system was used for the computer to avoid the inherent disadvantages that electronic analog computers present for problems of very long solution times. The electromechanical analog computer has a high order of reliability and contains no vaccum tubes, commutators, slip rings, relays, or aluminum electrolytic capacitors. It is insensitive to transient disturbarce. In the event of failure of components or interruption of line voltage, it will retain existing information. The computer was designed for ~ 1% accuracy in Xe/ sup 135/ concentration readings. (W.D.M.)
In this study, wood samples were exposed to light irradiations (direct sunlight, xenon lamp, mercury vapour lamp) and thermal treatments were carried out in dry- and in humid conditions at 90degreeC. One part of the samples was covered by an aluminium plate during light irradiation. The samples under the aluminium plate also suffered considerable chemical changes, monitored by infrared technique and colour measurement. The sunlight produced greater colour change under the aluminium plate than the artificial light sources. During light irradiation, the carbonyl band having two maximum at 1700 and 1746cm-1 increased and the peak of the aromatic skeletal vibration arising from lignin (1510cm-1) decreased together with the guaiacyl vibrations at 1275cm-1. There was absorption decrease at 1174c...
We have previously reported that periventricular structures are hypoperfused in attention deficit and hyperactivity disorder (ADHD). This study has expanded the number of patients, who were divided into two groups: six patients with pure ADHD, and 13 patients with ADHD in combination with other neurologic symptoms. By using xenon 133 inhalation and emission tomography, the regional cerebral blood flow distribution was determined and compared with a control group. Striatal regions were found to be hypoperfused and, by inference, hypofunctional in both groups. This hypoperfusion was statistically significant in the right striatum in ADHD, and in both striatal regions in ADHD with other neuropsychologic and neurologic symptoms. The primary sensory and sensorimotor cortical regions were highly perfused. Methylphenidate increased flow to striatal and posterior periventricular regions, and tended to decrease flow to primary sensory regions. Low striatal activity, ...
We demonstrate that the nanoparticle formation during laser ablation of metals by short (of a few tens of ps) laser pulses strongly depends on the concentration of surrounding gas. While, at vacuum conditions, nanoparticle formation shows very ''sharp'' atomic force microscope images of aggregated clusters, following with clear appearance of plasmon resonance on the absorption spectra of deposited films, an addition of gas particles starts to decrease the probability of cluster formation. This process shows a threshold for both helium (33 torr) and xenon (12 torr) above which no surface plasmon resonance and correspondingly no observable nanoparticles on the deposited surfaces were detected. The destruction of nanoparticle formation was attributed to the negative influence of surrounding gas particles on ablated particles aggregation. (orig.)
Encapsulation of a unique isotopic blend of krypton and xenon gas employs a special application of laser technology. The encapsulated gas is then used as the primary medium for detection and identification of failed nuclear fuel rods. The use of gas tagging as a means of detecting and identifying failed nuclear fuel rods has been successfully demonstrated and used by the Argonne National Laboratory, Experimental Breeder Reactor (EBR-2) Project, and the Westinghouse Hanford Company (WHC), Fast Flux Test Facility (FFTF) Fast Breeder Reactor Program. The Power Reactor and Nuclear Fuel Development Corporation (PNC) of Japan has selected this leak detection system for use in their MONJU Prototype Reactor fuel assemblies. The MONJU reactor is almost identical in design to the highly successful FFTF reactor, which is currently in standby status.
By using megaelectronvolt /sup 4/He ion backscattering techniques and transmission electron microscopy, the authors have investigated the interactions of ion beams with thin film structures in a number of silicide-forming systems. The mixed layer was found to be an equilibrium compound for near-noble metals and an amorphous phase for refractory metals. Differences in behavior have also been observed in near-noble metal systems. For palladium, the Pd/sub 2/Si phase grew with ion dose and remained crystalline up to high dose. For nickel, the compound Ni/sub 2/Si was formed initially and became amorphous on prolonged irradiation. All the results indicate the significance of atomic mobility at target temperatures in determining the phase formation and in explaining the sensitivity of the silicides to ion bombardment.
The obtained results in presently study demonstrate that the feasibility of the detection of the sentry ganglion in cervix uterine cancer using a boarding by laparoscopic via, being necessary the use of twice labelled as much with patent blue and radioisotope (colloid of labelled rhenium with "9"9"mTc, total dose of 3 MCi) to achieve the identification of the ganglion. (Author)
A procedure for the determination of lead in various biological and environmental samples by "2"0"3Pb radioisotope dilution substoichiometric method is presented. The accuracy of the method by comparison with the literature values of reference materials appears to be good. The standard deviation of the method is less than 10%, and detection limit is about 0.1 #mu#g of lead. (author) 5 refs.
The myocardial infarct induced by isoproterenol in spontaneously hypertensive rats accumulates higher activities of /sup 99/sup(m)Tc-PM tetracycline compared with the cardiac infarct in normotensive rats caused by the same method. The isoproterenol model of the myocardial necrosis was induced in intact rats without opening the thorax and is a convenient method for experimental radioisotope studies.
This paper extends the analytical procedure described in another paper in these proceedings to analyze a variety of compact and light-weight OSC-designed radioisotope-heated generators. Those generators employed General Purpose Heat Source (GPHS) modules and a converter containing sixteen AMTEC cells of OSC`s revised five-tube design with enhanced cell wall reflectivity described in a companion paper in these proceedings. OSC found that the performance of the generator is primarily a function of the thermal insulation between the outside of the generator`s 16 cells and the inside of its wall. After examining a variety of insulation options, it was found that the generator`s performance is optimized by employing a hybrid insulation system, in which the space between the cells is filled with fibrous Min-K insulation, and the generator walls are lined with tapered (i.e., graded-length) multifoil insulation. The OSC design results in a very compact generator, with ...
This illustrated booklet describes the fission process; the use of uranium to produce power in nuclear power stations (and a brief explanation of the differences between the principal types of reactor); the formation of plutonium and fission products; radioactive wastes and their management; nuclear fusion and a conceptual fusion reactor; alpha, beta and gamma radiations; radioisotopes and their applications. (U.K.).
Several computer assisted processing and display methods are evaluated using a series of 100 normal brain scintigrams, 50 of which have had single 'mathematical tumours' superimposed. Using a standard rating system, or in some cases quantitative estimation, LROC curves are generated for each method and compared. (author).
In this paper we review and classify the various patterns of isosteric heat versus loading for adsorption of gases on graphitised thermal carbon black at temperatures ranging from below the 3D triple point to temperatures above it, but less than the 3D critical point. We have identified the features of heat curve and highlighted the microscopic origin of these features. The patterns vary with temperature and with the relative strength of the fluid-fluid interaction and solid-fluid interaction. For simple adsorptives (by simple we meant there is no strong association between fluid particles), the heat curve is typified by fluid-fluid attraction and layering phenomena. For adsorptives showing strong association such as water, ammonia and methanol, the heat curve essentially begins below the condensation heat and then approaches it as loading is increased. This is mainly due to the strong hydrogen bonding in these fluids. A third group includes adsorptives such as benzene, where the heat ...
A noninvasive, simplified method using inhalation of stable xenon (Xe{sup s}) and computed tomographic (CT) scanning to estimate regional cerebral blood flow (rCBF) and regional partition coefficient (r{lambda}) is described. Twenty-four patients with cerebrovascular occlusive disease and six volunteer controls inhaled 30% Xe{sup s} and 70% oxygen for 180 seconds and exhaled for 144 seconds during serial CT scanning without denitrogenation. The end-tidal Xe{sup s} concentration was continuously monitored with a thermoconductivity analyzer to determine the build-up range (A value) and build-up rate constant (K value) for arteries with the curve fitting method. The time-CT number (Hounsfield unit) curve for cerebral tissue during the Xe{sup s} washin and washout phases was used to calculate r{lambda} and rCBF using least squares curve fitting analysis. The resultant r{lambda} and rCBF map demonstrated a reliable distribution between the gray and white matter, and ...
A noninvasive, simplified method using inhalation of stable xenon (Xe"s) and computed tomographic (CT) scanning to estimate regional cerebral blood flow (rCBF) and regional partition coefficient (r#lambda#) is described. Twenty-four patients with cerebrovascular occlusive disease and six volunteer controls inhaled 30% Xe"s and 70% oxygen for 180 seconds and exhaled for 144 seconds during serial CT scanning without denitrogenation. The end-tidal Xe"s concentration was continuously monitored with a thermoconductivity analyzer to determine the build-up range (A value) and build-up rate constant (K value) for arteries with the curve fitting method. The time-CT number (Hounsfield unit) curve for cerebral tissue during the Xe"s washin and washout phases was used to calculate r#lambda# and rCBF using least squares curve fitting analysis. The resultant r#lambda# and rCBF map demonstrated a reliable distribution between the gray and white matter, and infarcted areas. rCBF ...
The papers presented at the symposium had covered three general areas in which isotopes could have been beneficially used. these areas are: -Water use and water use efficiency studies. -Ground water investigations -Water problems in the arab countries. The individual papers had dealt with these subjects: -Hydrological research in the arab countries by use of radioisotopes. -The perspectives of use of radioisotopes in hydrological studies in Syria. -Water use efficiency and sub-soil water studies. -Sea water inclusion in a coast el aquifers in Lebanon. -Irrigation requirements of crops in Lebanon as determined by a Neutron probe with reference to other methods. -The use of the neutron moisture meter and other methods of the determination of the evapotranspiration of maize. -Ground water investigations, dating and nuclear methods applied to hydrology. -Ground water investigation in Wa di El-Nat run, U.A.R. -Velocity distribution along the pumped ...
Thermophotovoltaic (TPV) systems are attractive possibilities for direct thermal-to-electric energy conversion, but have typically required the use of black body radiators operating at high temperatures. Recent advances in both the understanding and performance of solid rare-earth oxide selective emitters make possible the use of TPV at temperatures as low as 1200K. Both selective emitter and filter system TPV systems are feasible. However, requirements on the filter system are severe in order to attain high efficiency. A thin-film of a rare-earth oxide is one method for producing an efficient, rugged selective emitter. An efficiency of 0.14 and power density of 9.2 W/KG at 1200K is calculated for a hypothetical thin-film neodymia (Nd2O3) selective emitter TPV system that uses radioisotope decay as the thermal energy source.
Population distribution, atmospheric change, X/Q, characteristics of terrestrial ecosystem around Seoul site were surveyed. Environmental radiation and radioactivities such as gross#alpha#, gross#beta#, Cs-137, Sr-90 and H-3 of various environmental samples were analyzed. The values of environmental radiation dose tended to increase gradually in the light of the recent five years' results of environmental radiation monitoring around the nuclear power plants from 1980 to 1984, however, the changes were not significant. In addition, continuous assessment of environmental radiation monitoring on the roofs of main building and life science building at KAERI showed that the environmental radiation dose tended to increase a little during the night time. Judging from the above results, it is concluded that environmental contamination level by radioactive materials could be ignored in the case of radioisotope production or experiment using ...
The purpose of this study is to develop the radioisotope tracer technology, which can be used in solving industrial and environmental problems and to build a strong tracer group to support the local industries. In relation to the tracer technology in 1999, experiments to estimate the efficiencies of a sludge digester of a waste water treatment plant and a submerged biological reactor of a dye industry were conducted. As a result, the tracer technology for optimization of facilities related to wastewater treatment has been developed and is believed to contribute to improve their operation efficiency. The quantification of the experimental result was attempted to improve the confidence of tracer technology by ECRIN program which basically uses the MCNP simulation principle. Using thin layer activation technique, wear of tappet shim was estimated. Thin layer surface of a tappet shim was irradiated by proton beam and the correlation between the measured activity loss ...
Volume sources is used for standard sources by radioactive measurement using Ge semiconductor detector of environmental sample, e.g. water, soil and etc. that require large volume. The commercial volume source used in measurement of the water sample is made of agar-agar, and that used in measurement of the soil sample is made of alumina powder. When the plastic receptacles of this two kinds of volume sources were damaged, the leakage contents cause contamination. Moreover, if hermetically sealing performance of volume source made of agar-agar fell, volume decrease due to an evaporation off moisture gives an error to radioactive measurement. Therefore, we developed the two type methods using unsaturated polyester resin, vinilester resin, their hardening agent and acrylicresin. The first type is due to dispersing the hydrochloric acid solution included the radioisotopes uniformly in each resin and hardening the resin. The second is due to dispersing the alumina ...
Lanthanum halide (LaBr_3:Ce) scintillators offer significantly better resolution (< 3% at 662 keV) relative to NaI(Tl) and have recently become commercially available in sizes large enough for the handheld, Radio-Isotope Identification Device (RIID) market. Drawbacks to lanthanum halide detectors, however, include internal radioactivity contributing to spectral counts, and a low-energy response which can cause detector resolution to be worse than that of NaI(Tl) below 100 keV. To study the potential of this new material for RIIDs we performed a series of measurements comparing a 1.5 x 1.5-inch LaBr_3:Ce detector with an Exploranium GR-135 RIID, which contains a 1.5 x 2.2-inch NaI(Tl) detector. Measurements were taken for short timeframes, as typifies RIID usage. Measurements included examples of naturally occurring radioactive material (NORM), typically found in cargo, and special nuclear materials. Some measurements were non-contact, involving short distances ...
A carbon-bonded carbon fiber (CBCF) insulation developed for a radioisotope heat source is made from chopped rayon fiber about 10..mu..m long, which is carbonized and bonded with phenolic resin particles. The CBCF is an excellent lightweight insulating material with a nominal density of 0.2 Mg/m/sup 3/ and a thermal conductivity of 0.24 W/(m-K) in vacuum at 2000/sup 0/C. (Several attributes that make CBCF particularly suitable for the heat source application have been identified.) These include light weight, low thermal conductivity, chemical compatibility, and hightemperature capabilities. The mechanical strength of CBCF insulation is satisfactory for the application. The basic fabrication technique was refined to eliminate undesirable large pores and cracks often present in materials fabricated by earlier techniques. Also, processing was scaled up to increase the fabrication rate by a factor of 10. The specific properties of the CBCF were tailored by adjusting ...
A carbon-bonded carbon fiber (CBCF) insulation developed for a radioisotope heat source is made from chopped rayon fiber about 10 ..mu..m in diameter and 250 ..mu..m long, which is carbonized and bonded with phenolic resin particles. The CBCF is an excellent lightweight insulating material with a nominal density of 0.2 Mg/m/sup 3/ and a thermal conductivity of 0.24 W/(m-K) in vacuum at 2000/sup 0/C. Several attributes that make CBCF particularly suitable for the heat source application have been identified. These include light weight, low thermal conductivity, chemical compatibility, and high-temperature capabilities. The mechanical strength of CBCF insulation is satisfactory for the application. The basic fabrication technique was refined to eliminate undesirable large pores and cracks often present in materials fabricated by earlier techniques. Also, processing was scaled up to increase the fabrication rate by a factor of 10. The specific properties of the CBCF ...
Possible use of stable radioisotopes in studies on nutrition and medicine problems that may be used in investigations of babies, children, pregnant women is shown. Attention is paid to behaviour of limited number of elements: hydrogen, carbon, nitrogen, oxygen. The IAEA plans implementation of a new coordinated research program on use of stable isotopes for studying nutrition problems and related diseases. The program emphasis will be placed on protein metabolism measurements and estimation of energy consumption in control population groups in developing countries.
Thermophotovoltaics is the science and technology associated with the direct generation of electricity from high temperature heat. Potential applications include combined heat and power, portable and auxiliary power, radioisotope space power, industrial waste heat recovery and concentrated solar power. This book aims at serving as an introduction to the underlying theory, overview of present day components and system arrangements, and update of the latest developments in the field. The emphasis is placed on the understanding of the critical aspects of efficient thermophotovoltaic system design. The aim is to assist researchers in the field. (orig.)
Carrier-free radioisotopes of tungsten, "1"7"6","1"7"7W, and their corresponding daughter radionuclides "1"7"6","1"7"7Ta, have been produced in holmium target by heavy ion activation with "1"6O"5"+ beam. An attempt has been made to separate these carrier-free radionuclides from bulk holmium target through LLX using cation exchanger HDEHP. (author)
Data from the power output of the radioisotope thermoelectric generators aboard the Cassini spacecraft are used to test the conjecture that small deviations observed in terrestrial measurements of the exponential radioactive decay law are correlated with the Earth-Sun distance. No significant deviations from exponential decay are observed over a range of 0.7 - 1.6 A.U. A 90% Cl upper limit of 0.84 x 10^-4 is set on a term in the decay rate of Pu-238 proportional to 1/R^2 and 0.99 x 10^-4 for a term proportional to 1/R.
Study of the rate of dissolution in simulated lung fluid of uranium from 3 different ore matrices and from refined uranium dioxide in an essentially all teflon extraction apparatus; the rate of dissolution of thorium from a nickel metal/2 percent thoria mixture; the effect of neutron irradiation of the studied materials upon the dissolution rates; and the adsorptions of the radioisotope tracers barium 133 (substitute for radium), lead 203 and thorium 234 upon the extraction system components.
Neon 19, a 17-second positron-emitting radioelement, is produced continously by 23 MeV alpha particle bombardment of oxygen. For a 12 ..mu..A particle current the method of preparation described delivers 14 mCi of neon 19 per min to the functional exploration room. The radiochemically pure radioactive gas is diluted in air and breathed continously by the patient lying under a positron tomographic camera. The regional lung ventilation distribution is obtained on 2 cm thick sections of organ with a transverse resolution of 17 mm. Quantification of the ventilation output per unit lung volume is contemplated.
In Japan, cosmetics claiming hormesis effect are available through Internet. Although these cosmetics show the contents, they never mention the minor elements and radioactive sources. The existence of radioisotopes, however, was observed by measurements of the gamma-rays with a HPGe detector. In this study, in order to clarify the contents of trace elements, the hormesis cosmetics including radioactive sources were analyzed using INAA, PGAA and NAA with multiple gamma-ray detection (NAAMG). Nineteen elements were analyzed quantitatively in hormesis cosmetics by INAA, PGAA and NAAMG and 16 elements were detected qualitatively by SEM-EPMA. (author)
The K_#beta#/K_#alpha# X-ray intensity ratios are measured for Mn and Fe and for six other elements with Z lying in the range 49<=Z<=82 following electron capture decay and photon excitation using "2"4"1Am and "5"7Co sources. High-resolution Si(Li) and HpGe detector systems were used in the experiments. The dependence of K_#beta#/K_#alpha# values on the mode of excitation in the case of Mn and Fe is attribuited to the chemical effects, while no such dependence is found for the high-Z elements.
COMPLIS is an experimental facility designed to carry out spectroscopic studies on radioisotopes produced by disintegration of elements available at CERN's Booster-ISOLDE on-line isotope separator. During recent series of experimental runs, hyperfine structure measurements have yielded information on nuclear moments and deformations of platinum and iridium isotopes. For the first time, population by #alpha#-decay from Hg was exploited to investigate "1"7"8"-"1"8"1Pt--the most neutron-deficient Pt isotopes yet studied. Successful measurements have recently been carried out on "1"8"2"-"1"8"9Ir.
This report was prepared in response to a request from the Nuclear Energy Research Advisory Committee (NERAC) subcommittee on ''Long-Term Isotope Research and Production Plans.'' The NERAC subcommittee has asked for a reply to a number of questions regarding (1) ''How well does the Department of Energy (DOE) infrastructure sme the need for commercial and medical isotopes?'' and (2) ''What should be the long-term role of the federal government in providing commercial and medical isotopes?' Our report addresses the questions raised by the NERAC subcommittee, and especially the 10 issues that were raised under the first of the above questions (see Appendix). These issues are related to the isotope products offered by the DOE Isotope Production Sites, the capabilities and condition of the facilities used to produce these products, the management of the isotope production programs at DOE ...
This is the quarterly progress review report for Wolsung NPP 2, 3, 4 NSSS design and engineering which evaluates the performance of project and describes the project highlight, manpower loading status, design and engineering and project related meeting by...
The sequential events and the inflammatory mediators that characterize disease onset and progression of ulcerative colitis (UC) are not well known. In this study, we evaluated the early pathologic events...Full Text Available
Progress is reported in the following areas: radioactivity control technology, FFTF sodium characterization system, corrosion and process control, and fuel failure monitoring systems for FFTF and CRBRP. (JWR)
Progress is reported in the following areas: metallurgy and ceramics (structure of materials, mechanical properties, physical properties), experimental research, and particle-solid interactions (irradiation effects on alloys). (DLC)
Most genetic changes that promote tumorigenesis involve dysregulation of G1 cell cycle progression. A key regulatory site in G1 is a growth factor–dependent restriction point (R) where cells...Full Text Available
SummaryAn overview of recent progress on the total synthesis of acetogenins from Annonaceae during the past 12 years is provided. These include mono-tetrahydrofurans, adjacent bis-tetrahydrofurans,...Full Text Available
Neurological disorders induced by long-term exposure to organic solvents typically have a slowly progressive clinical course, which may be arrested or even reversed following discontinuation of exposure....Full Text Available
Breast cancer is a progressive and potentially fatal disease that affects women of all ages. Like all progressive diseases, early and reliable diagnosis is the key for successful treatment and annihilation....Full Text Available
Research progress is reported in 20 activities under the headings: spent fuels, defense waste management, commercial waste management, remedial action, and conventional reactors. Separate entries were prepared for each activity.
Progress is reported in fabrication and coating activities being conducted for the weapons program, nuclear test program, nuclear design program, magnetic fusion program, and miscellaneous applications. (DLC)
Progress is briefly summarized for a large number of projects in the areas of research instruments, measurement and controls engineering, reactor systems, and maintenance management. (LEW)
Progress is reported in the following subject areas: (1) chemistry of the arogenate molecule; (2) plant enzymology at the organismal level; (3) isolation of regulatory mutants in tobacco; and (4) stability of the haploid state in Nicotiana sylvestris.
The development of comfort in buildings throughout the centuries was influenced by the demand for progress, wealth and innovation in various respects. At present, it seems that progress may only be possible by taking into account the environment and creat...
This progress report presents a detailed description of the background, technology and application, and Statement of Work for the development of a coal-fired pulse combustor for residential space heating.
Gentilly 2, Point Lepreau, Cordoba and Wolsung are the first 600 MW CANDU nuclear generating stations to be built. Progress in their construction and in the remaining design work for these stations is discussed. (LL).
SummaryFor mammalian somatic cells the importance of microtubule cytoskeleton integrity in interphase cell cycle progression is uncertain. The loss, diminishment, or stabilization...Full Text Available
BackgroundTraditionally in pediatric HIV, the CD4+ T-lymphocyte percent is used in monitoring disease progression due to the variability in absolute CD4+ T-lymphocyte...Full Text Available
... The rounds were initiated by an exploding bridgewire detonator (EBW) and the ionisation probes were progressively cloud by the detonation front. ...
... in tactics, techniques, and procedures (TTP), such as ... flow across the Afghanistan-Pakistan border, specifically ... The funds from the NATO ANA Trust ...
... Progress: For a one-dimensional two-phase degenerate Stefan problem, it was proved that the boundary and the solutions up to the boundary are C ...
The three determination methods of alpha activity ration are described, namely geometric progression method, extrapolation method and curve fitting method. The validity of the geometric progression method is demonstrated in the present work. The "2"3"8Pu/("2"3"9Pu + "2"4"0Pu) evaluated by extrapolation method is compared with that by geometric progression method. Also, the "2"3"8Pu/("2"3"9Pu + "2"4"0Pu)evaluated by curve fitting method is compared with that by geometric progression.
the progressive simplification of composite sandwich panels. The equations ... The thermal and structural behavior of composite sandwich panels with a ...
A theoretical model, which describes subband gap photoexcitation involving localized electronic states, was developed. The escape probability of a charge carrier trapped in a localized state is considered via Poole-Frenkel, direct tunneling, or phonon-assisted tunneling processes, as competing escape mechanisms. Photoelectrochemical experiments were performed on the passive films formed on zirconium and amorphous iron-zirconium alloys and on pure HfO/sub 2/ films and HfO/sub 2/ films implanted with varying concentrations of xenon. These films were found to possess some degree of disorder depending on the substrate, the thickness of the film, and the extent of implantation. The spectral dependence of the photocurrent in all of the films studied is considerably different from what was found for crystalline passive films. The potential dependence of the photocurrent yields Poole-Frenkel behavior. Reverse tunneling processes were also observed at low photon energies ...
In this paper, we investigate the effect of the solid surface on the fluid-fluid intermolecular potential energy. This modified fluid-fluid interaction energy due to the inducement of a solid surface is used in the grand canonical Monte Carlo (GCMC) simulation of various noble gases, nitrogen, and methane on graphitized thermal carbon black. This effect is such that the effective interaction potential energy between two particles close to surface is less than the potential energy if the solid substrate is not present. With this modification the GCMC simulation results agree extremely well with the experimental data over a wide range of pressures while the simulation results with the unmodified potential energy give rise to a shoulder near the neighborhood of monolayer coverage and the significant overprediction of the second and higher layer coverages. In particular the unmodified GCMC results exhibit very sharp change in those higher layers while the experimental data have a much ...
A joint US/Russia program is being conducted to develop, fabricate, launch, and operate a solar dynamic demonstration system on Space Station Mir. The goal of the program is to demonstrate and confirm that solar dynamic power systems are viable for future space applications such as the International Space Station Alpha. The major components of the system include a heat receiver, a closed Brayton cycle power conversion unit, a power conditioning and control unit, a concentrator, a radiator, a thermal control system, and a Space Shuttle carrier. This paper discusses the design of the heat receiver component. The receiver comprises a cylindrical cavity, the walls of which are lined with a series of tubes running the length of the cavity. The engine working fluid, a mixture of xenon and helium, is heated by the concentrated sunlight incident on these tubes. The receiver incorporates integral thermal storage, using a eutectic mixture of lithium fluoride and calcium ...
During the operation of the Fast Flux Test Facility (FFTF), radioactive gases, primarily xenon and krypton, will be produced which will require processing and storing. Two systems have been installed in the FFTF for handling these gases: (1) one to handle, primarily, the reactor cover gas system, and (2) a second to handle the cells and cover gas systems, other than the reactor, whose atmosphere may become contaminated. The system that processes the reactor cover gas, which is argon, is called the Radioactive Argon Processing System (RAPS). The effluent argon from RAPS will normally be sufficiently decontaminated to allow its reuse as the reactor cover gas. If the radioactive level in the RAPS becomes too high, the exhaust stream will be diverted to the Cell Atmosphere Processing System (CAPS), a system which can function as a backup to RAPS. The design and operation of the RAPS and CAPS systems are described and certain safety aspects of the systems are discussed. ...
This report provides a summary of progress for the project {open_quotes}Evaluation of the Geologic Relations and Seismotectonic Stability of the Yucca Mountain Area, Nevada Nuclear Waste Site Investigation (NNWSI).{close_quotes} A similar report was previously provided for the period of 1 October 1991 to 30 September 1992. The report initially covers the activities of the General Task and is followed by sections that describe the progress of the other ongoing tasks.
Noninvasive and simplified methods for estimating regional cerebral blood flow (CBF) and regional partition coefficient ({lambda}) using the inhalation of stable xenon (Xe{sup s}) and computed tomographic (CT) scanning are described. Thirty percent Xe{sup s} in 70% oxygen was inhaled for 240 seconds and exhaled for 160 seconds during serial CT scanning without denitrogenation in 26 patients with cerebrovascular diseases and four volunteer controls. During the investigation, the end-tidal Xe{sup s} concentration was continuously monitored with a thermoconductivity analyzer to determine the build-up range (A value) and build-up rate constant (K value) of the artery by the curve fitting method. Calculated A and K values were corrected by the following formulae reported previously: for patients aged 0-20 years, A{sub e} = 0.75A{sub a} + 2.15, K{sub e} = 0.67K{sub a} + 0.69; 21-40 years, A{sub e} = 0.56A{sub a} + 3.24, K{sub e} = 0.38K{sub a} + 1.12; 41-60 years, A{sub ...
Noninvasive and simplified methods for estimating regional cerebral blood flow (CBF) and regional partition coefficient (#lambda#) using the inhalation of stable xenon (Xe"s) and computed tomographic (CT) scanning are described. Thirty percent Xe"s in 70% oxygen was inhaled for 240 seconds and exhaled for 160 seconds during serial CT scanning without denitrogenation in 26 patients with cerebrovascular diseases and four volunteer controls. During the investigation, the end-tidal Xe"s concentration was continuously monitored with a thermoconductivity analyzer to determine the build-up range (A value) and build-up rate constant (K value) of the artery by the curve fitting method. Calculated A and K values were corrected by the following formulae reported previously: for patients aged 0-20 years, A_e = 0.75A_a + 2.15, K_e = 0.67K_a + 0.69; 21-40 years, A_e = 0.56A_a + 3.24, K_e = 0.38K_a + 1.12; 41-60 years, A_e = 0.91A_a + 1.95, K_e = 0.38K_a + 1.32; over 61 years, ...
The 3 MW TRIGA Mark-II research reactor of Bangladesh Atomic Energy Commission (BAEC) has been operating since September 14, 1986. The reactor is used for radioisotope production ("1"3"1I, "9"9"mTc, "4"6Sc), various R and D activities and manpower training. The reactor has been operated successfully since it's commissioning with the exception of a few reportable incidents. Of these, the decay tank leakage incident of 1997 is considered to be the most significant one. As a result of this incident, reactor operation at full power under forced-convection mode remained suspended for about 4 years. During that time, the reactor was operated at a power level of 250 kW so as to carry out experiments that require lower neutron flux. This was made possible by establishing a temporary by pass connection across the decay tank using local technology. The other incident was the contamination of the Dry Central Thimble (DCT) that took place in March 2002 when a pyrex vial ...
High-flux neutron sources are continuing to be of interest both in Canada and internationally to support materials testing for advanced power reactors, new developments in extracted-neutron-beam applications, and commercial production of selected radioisotopes. The advanced MAPLE reactor concept has been developed to meet these needs. The advanced MAPLE reactor is a new tank-type D_2O reactor that uses rodded low-enrichment uranium fuel in a compact annular core to generate peak thermal-neutron fluxes of 1 x 10"1"9 n#centre dot#s"-"1 in a central irradiation rig with a thermal power output of 50 MW. Capital and incremental development costs are minimized by using MAPLE reactor technology to the greatest extent practicable.
The cross section and activity profile of different radioisotopes produced by #alpha#-induced nuclear reaction on natural zirconium, have been obtained by stacked foil activation using 40 MeV #alpha#-particles from Variable Energy Cyclotron (VEC) machine at Calcutta. The activity profile would be used to study the surface loss of zircaloy materials of engineering components by thin layer activation (TLA) technique. Generally, isotopes with suitable #gamma#-rays and long half-lives are the most useful in TLA technique, e.g., "9"2Nb, "9"5"gNb and "9"5Zr. (author). 2 refs., 1 tab.
The project was designed to solve the infra structural problem required for commercialization of food irradiation. In improvement of physical properties of corn starch, gamma irradiation was effective for increasing glucose productivity and for substituting traditional modified starches (acid modified starch, oxidized starch). In immobilization of microorganisms, the mass production method of natural red pigment was developed by using immobilized mold pellets. In Korean medicinal plants, 10 kGy gamma irradiation was effective for improving sanitary quality and increasing extraction yield. In evaluation of wholesomeness, gamma irradiated red ginseng could be safe on the genotoxic point of view. And also, six items of irradiated foods approved for human consumption from Korea ministry of health and welfare in May 19, 1995. 30 figs, 20 tabs, 54 refs. (Author).
Heavy ion irradiation on tantalum metal target with 57 MeV {sup 11}B{sup 4+} leads to the production of no-carrier-added radioisotopes of platinum, {sup 187,188}Pt and iridium, {sup 187,188}Ir in the matrix, which have been effectively separated from the bulk target and from each other with suitable anion exchangers employing liquid-liquid extraction (LLX). Also {sup 188,189}Pt and {sup 188,189}Ir radionuclides have been produced, from their short-lived precursors {sup 188,189}Au, in {sup 12}C{sup 6+} irradiated tantalum matrix. Gamma-spectroscopy has been utilised to determine the production, extent of separation and purity of the radiotracers at different stages of the experiment. (orig.)
Bismuth radioisotopes, produced by 50-MeV proton bombardment of a lead target in a cyclotron, are separated from the lead target material by ion-exchange chromatography on a column containing 5.0 ml of Chelex 100. After a decay period of 24 hr, the /sup 203/Pb formed in situ is eluted from the column and then separated from /sup 200/Tl and /sup 201/Tl on a second ion-exchange column containing 0.5 ml of Chelex 100. Separations are sharp and carrier-free /sup 203/Pb is obtained.
This report is the result of field work performed at the former White Point Nike Missile Site, San Pedro, California. The Hazardous Waste Remedial Actions Program tasked the Oak Ridge National Laboratory Pollutant Assessments Group in Grand Junction, Colo., with this project. The objective was to determine whether or not radioisotopes possibly associated with past Department of Defense (DOD) operations were present and within accepted background levels. The radiation survey was accomplished by performing three independent radiation surveys, both outdoors and indoors, and random soil sampling. Initially, the site was land surveyed to develop a grid block system. A background radiation investigation was performed out in the San Pedro area.
The calculated radioactive waste inventories of the Turkey Point pressurized water fission reactor (PWR) and the Starfire conceptual fusion tokamak are compared as a function of time from initial start-up to 10,000 years after decommissioning. Only material out of reactor at least one year is considered. The total activity in Ci/W(th) of the Starfire tokamak is slightly greater than that of the PWR during the active lifetimes of the two reactors and beyond 1000 years. However, using reduced activation materials in Starfire can result in about 1/2000 as much long-lived radioactivity as in the fission reactor. It is stressed that comparison of wastes on this basis is not straightforward, since the radioisotopes and methods required for their disposal are different for fusion and fission reactors. 2 refs., 1 fig., 2 tabs.
The radiation control carried out in Atomic Energy Research Institute, Kinki University, for the reactor installation and the tracer/accelerator facilities from April, 1981, to March, 1982, is described. The reactor was operated for total 1057.1 hours at the maximum heat output of 1 W. The persons subject to radiation protection as of April, 1981, were 126 persons in all, including 23 in radiation work and 11 in X-ray work, etc. The contents of this report are as follows: personnel monitoring (health examination, the control of individual exposure dose); laboratory monitoring (the measurement of area dose rate, radioactive concentration in air and water, and surface contamination density); field monitoring (environmental ..gamma..-ray dose rate, radioactive concentration in environmental samples); the use of unsealed radioisotopes, etc.
Nuclear power has been considered for space applications since the 1960s. Between 1955 and 1972 the US built and tested over twenty nuclear reactors/ rocket-engines in the Rover/NERVA programs. However, changes in environmental laws may make the redevelopment of the nuclear rocket more difficult. Recent advances in fuel fabrication and testing options indicate that a nuclear rocket with a fuel form significantly different from NERVA may be needed to ensure public support. The Center for Space Nuclear Research (CSNR) is pursuing development of tungsten based fuels for use in a NTR, for a surface power reactor, and to encapsulate radioisotope power sources. The CSNR Summer Fellows program has investigated the feasibility of several missions enabled by the NTR. The potential mission benefits of a nuclear rocket, historical achievements of the previous programs, and recent investigations into alternatives in design and materials for future systems will be discussed.
Improved radionuclide generator include a substantially insoluble salt of a radioactive parent which may be directly packed in column for subsequent elution of the daughter radionuclide. An improved 188Re generator was prepared by reacting a radioactive tungsten (188W) as parent radionuclide incorporated with aluminum chloride to obtain an insoluble radioactive aluminum tungstate matrix. The investigated matrix was characterized on the basis of the chemical composition, IR, thermal analysis and mechanical stabilities. The factors affecting the elution performance were studied such as influence of pH, molar ratio and drying temperature. From the obtained data, the molar ratio W:Al was 1.5:1 at pH?=?4, the matrix dried at 105??C for 2 h. Chromatographic and multichannel analysis has been cur...
The US Department of Energy (DOE) has millions of gallons of high level nuclear waste stored in underground tanks at Hanford, Washington and Savannah River, South Carolina. These tanks will eventually be emptied and decommissioned. This will leave a residue of sludge adhering to the interior tank surfaces that may contaminate groundwaters with radionuclides and RCRA metals. Experimentation on such sludges is both dangerous and prohibitively expensive so there is a great advantage to developing artificial sludges. The US DOE Environmental Management Science Program (EMSP) has funded a program to investigate the feasibility of developing such materials. The following text reports on the success of this program, and suggests that much of the radioisotope inventory left in a tank will not move out into the surrounding environment. Ultimately, such studies may play a significant role in developing safe and cost effective tank closure strategies.
Nuclear approaches for compositional characterization has bright application prospect in forensic perspective towards assessment of nature and origin of seized material. The macro and micro physical properties of nuclear materials can be specifically associated with a process or type of nuclear activity. Under the jurisdiction of nuclear analytical chemistry as well as nuclear forensics, thrust areas of scientific endeavor like determination of radioisotopes, isotopic and mass ratios, analysis for impurity contents, arriving at chemical forms/species and physical parameters play supporting evidence in forensic investigations. The analytical methods developed for this purposes can be used in international safeguards as well for nuclear forensics. Nuclear material seized in nuclear trafficking can be identified and a profile of the nuclear material can be created
The distribution of Lipiodol in the liver and lungs following arterial or portal injection was studied in normal (n=55) and cirrhotic rats (n=20). Using magnified xeroradiography and radioisotope labeled tracers, it was found that Lipiodol was deposited mainly in the liver and lung after either arterial or portal administration. In control rats after arterial injection, deposits in the lung peaked after 2 hours and gradually declined over 48 hours; whereas after portal injection, the deposit steadily increased for 48 hours. Twenty-five percent of cirrhotic rats demonstrated a Lipiodol-induced miliary pattern in the lung. An increased number of portosystemic shunts in cirrhotic rats was also noted. These results suggest that cirrhosis of the liver may be a potential risk factor for developing pulmonary complications after Lipiodol administration. (orig.).
A LLX procedure for carrier-free separation of the radioisotopes, {sup 47}Sc, {sup 48}V and {sup 48},{sup 49},{sup 51}Cr, the 40 MeV {alpha}-particle activation products of titanium has been developed. Sequential separations of the radionuclides produced in the titanium matrix through the nuclear reactions ({alpha}, {alpha}p{chi}n), ({alpha}, p{chi}n) and {alpha}, ({chi}n) have been performed through LLX from aqueous H{sub 2}SO{sub 4} and HClO{sub 4} acid media using the liquid cation exchanger, HDEHP, as an extractant. Purity of the carrier-free radiotracers at different stages of their separations has been verified by {gamma}-ray spectrometry. (author).
The K/sub ..beta..//K/sub ..cap alpha../ X-ray intensity ratios are measured for Mn and Fe and for six other elements with Z lying in the range 49 less than or equal to Z less than or equal to 82 following electron capture decay and photon excitation using /sup 241/Am and /sup 57/Co sources. High-resolution Si(Li) and HpGe detector systems were used in the experiments. The dependence of K/sub ..beta..//K/sub ..cap alpha../ values on the mode of excitation in the case of Mn and Fe is attributed to chemical effects, while no such dependence is found for the high-Z elements.
Plutonium oxide fuel pellets for powering radioisotopic thermoelectric generators for NASA space vehicles are encapsulated in iridium which has been grain-boundary-stabilized with thorium and aluminum. After aging for 6 months at 1310/sup 0/C under vacuum, enhanced grain growth is observed in the near-surface grains of the iridium next to the PuO/sub 2/. Examination of the grain boundaries by AES and SIMS shows a depletion of thorium and aluminum. Iron, chromium, and nickel from the fuel were found to diffuse into the iridium along the grain boundaries. Enhanced grain growth appears to result from thorium depletion in the grain boundaries of the near-surface grains next to the fuel. However, in one instance grain growth was slowed by the formation of thorium oxide by oxygen diffusing up the grain boundaries.
Hydrogen cyanide (HCN) production by Pseudomonas aeruginosa in a synthetic medium is stimulated by the presence of glycine. Methionine enhances this stimulation but will not substitute for glycine as a stimulator of cyanogenesis. Threonine and phenylalanine are effective substitutes for glycine in the stimulation of HCN production. Glycine, threonine, and serine are good radioisotope precursors of HCN, but methionine and phenylalanine are not. Cell extracts of P. aeruginosa convert (/sup 14/C)threonine to (/sup 14/C)glycine. H14CN is produced with low dilution of label from either (1-/sup 14/C)glycine or (2-/sup 14/C)glycine, indicating a randomization of label either in the primary or secondary metabolism of glycine. When whole cells were fed (1,2-/sup 14/C)glycine, cyanide and bicarbonate were the only radioactive extracellular products observed.
Particle accelerators are constructed and operated for a wide variety of applications. In particle physics - the branch of physics that studies the elementary constituents of matter and forces between them - high energy accelerators are used to look deep into the structure of matter. Medical particle accelerators are used for example in medicine to treat tumours [31], in imaging techniques such as Positron Emission Tomography (PET) [24], or for the radio-isotopes production. They also serve in many other industrial branches, e.g. geology, radiocarbon dating [39], molecular complex spectroscopy, lithography, food preservation etc. The eld of accelerator technology draws knowledge and expertise from a wide range of scientic disciplines and uses the latest technical knowledge. The incomplete list of covered disciplines includes mathematics, physics, electronics, computing, electromagnetic eld technology, microwave technology, cryogenics, vacuum technology, special ...
The nuclear complex in Tarapur, Maharashtra is a multi facility nuclear site comprising of power reactors and research facilities. Each facility has independent liquid effluent discharge line to Arabian Sea. Experimental studies were conducted to evaluate dilution factors in the aquatic environment using liquid effluent releases as tracer from one of the facilities. 3H and 137Cs radioisotopes present in the routine releases were used as simulated tracer nuclides. The dilution factors(D.F) observed for tritium were in the range of 20-20000 in a distance range of 10 m to 1500 m respectively and for 137Cs the D.F. were in the range of 50 to 900 over a distance range of 10-200 m. The paper describes the analytical methodology and sampling scenarios and the results of dilution factors obtained for Tarapur aquatic environment. (author)
The excitation functions of the reactions "9"8Mo(d,p)"9"9Mo and "1"0"0Mo(d,p)"1"0"1Mo have been determined by irradiation of stacked foils with deuterons of energies less than 13 MeV and non-destructive determination of the absolute activity of the Mo radioisotopes by semiconductor #gamma#-ray spectrometry. From the excitation functions, the thick-target yields and the saturation production rates of "9"9Mo and "1"0"1Mo for deuteron energies of 13.0 MeV and 11.7 MeV have been calculated. Implications for the production of "9"9Mo for generators of sup(99m)Tc are discussed. (author).
This study evaluated the clinical efficacy of treatment with oral risedronate (17.5?mg once daily) for 8?weeks in 11 Japanese patients with Paget?s disease of bone (PDB). Risedronate suppressed the excessive bone turnover associated with PDB and improved several biochemical markers, including serum alkaline phosphatase (ALP), serum bone-specific ALP (BALP), urinary deoxypyridinoline (DPD), and urinary cross-linked N-telopeptide of type 1 collagen (NTX). These markers began to decrease within about 2?weeks after the initiation of treatment in most patients, and the response persisted for up to 40?weeks after the cessation of treatment. Risedronate reduced pain by week 24 in most patients. According to quantitative bone scintigraphy, the lesion with the highest radioisotope (RI) uptake showe...
Nuclear forensic science has become increasingly important for global nuclear security. However, many current laboratory analysis techniques are based on methods developed without the imperative for timely analysis that underlies the post-detonation forensics mission requirements. Current analysis of actinides, fission products, and fuel-specific materials requires time-consuming chemical separation coupled with nuclear counting or mass spectrometry. High-temperature gas-phase separations have been used in the past for the rapid separation of newly created elements/isotopes and as a basis for chemical classification of that element. We are assessing the utility of this method for rapid separation in the gas-phase to accelerate the separations of radioisotopes germane to post-detonation nuclear forensic investigations. The existing state of the art for thermo chromatographic separations, and its applicability to nuclear forensics, will be reviewed. (author)
In FY1994, JMTR was in operation during 4 operation cycles with low enriched Uranium(LEU,20%) fuel for irradiation study of nuclear fuels and materials and for radioisotope production. Irradiation studies were carried out using capsules, Oarai Gas Loop-1(OGL-1), Oarai Shroud Facility(OSF-1) and hydraulic rabbits irradiation facilities in support of LWR, FBR, HTTR and thermonuclear reactor. Irradiation studies on blanket materials were intensively carried out. Power ramping tests were carried out and the future program is under consideration. For R and D works, neutron spectrum evaluation technology, re-instrumentation technique for irradiation fuel rod, remote controlled SEM apparatus and examination technique with miniaturized specimens were successfully developed. (author).
A progress report is presented on development of the WIPS computer code, a special purpose code for analysis of whip and impact in nuclear power piping. The computer code and final report are expected to be complete in December 1981. This progress report is an incomplete version of the final report, representing approximately 40% of the volume of the final report. Some sections in the report are complete, some are partially complete, and others are omitted. The report is intended to inform prospective WIPS users of the procedures, theories, and documentation standards which will be used for the computer code and the final report.
Construction of high voltage transmission lines in a difficult hilly terrain within the limited time frame calls for the adoption of modern management tools for controlling the progress. The activity on node network system for such works, in which parallel and overlapping activities are involved is highly useful and is being used in Himachal Pradesh State Electricity Board. This network system has helped the Board to provide an effective and efficient mode of progress reporting at all levels of functioning. A remarkable example is the control of construction of 190 km - 200 kV dc transmission line within four years and six months.
In nuclear fuel, in approximately one quarter of the fissions, one of the two formed fission products is gaseous. These are mainly the noble gases xenon and krypton with isotopes of xenon contributing up to 90% of the product gases. These noble fission gases do not combine with other species, and have a low solubility in the normally used uranium oxide matrix. They can be dissolved in the fuel matrix or precipitate in nanometer-sized bubbles within the fuel grain, in micrometer-sized bubbles at the grain boundaries, and a fraction also precipitates in fuel pores, coming from fuel fabrication. A fraction of the gas can also be released into the plenum of the fuel rod. With increasing fission, and therefore burn-up, the ceramic fuel material experiences a transformation of its structure in the 'cooler' rim region of the fuel. A subdivision occurs of the original fuel grains of few microns size into thousands of small grains of ...
This Fact Sheet presents the mission of the West Valley Demonstration Project and information on the 1994 pollution prevention and recycling accomplishments.
Mitochondrial dysfunction has been implicated in premature aging, age-related diseases, and tumor initiation and progression. Alterations of the mitochondrial genome accumulate both in aging tissue...Full Text Available
BackgroundUnderstanding the mechanisms that control rates of disease progression in humans and other species is an important area of research relevant to epidemiology and to translating...Full Text Available
This is the monthly progress report for the Savannah River Technology Center, which covers the following areas of interest, Tritium, Separation processes, Environmental Issues, and Waste Management.
The installation and performance of a water source heat pump in Minnesota are discussed. The operating cost was found to be higher than expected. (MHR)
Knowledge about retinal photoreceptor signal transduction and the visual cycle required for normal eyesight has expanded exponentially over the past decade. Substantial progress in human genetics...Full Text Available
Insofar as international conferences reflect the state of development of the subject under discussion, they provide an opportunity to question, at a rather fundamental level, the direction of and progress...Full Text Available
The identification of individuals at risk for Alzheimer's disease (AD) is essential for the timely administration of treatment approaches aimed at slowing the onset or progression of the disease....Full Text Available
Tumour hypoxia represents a significant challenge to the curability of human tumours leading to treatment resistance and enhanced tumour progression. Tumour hypoxia can be detected by non-invasive and...Full Text Available
Tobacco use has been recognized to be a significant risk factor for the development and progression of periodontal disease. Its use is associated with increased pocket depths, loss of periodontal attachment,...Full Text Available
Much progress has been made in understanding the complex pharmacokinetics of trichloroethylene (TCE). Qualitatively, it is clear that TCE is metabolized to multiple metabolites either locally or into...Full Text Available
An acute exudative Escherichia coli pyelonephritis rat model was used to study the influence of progressive pyelonephritis on the efficacy of antibiotic treatment. In this model, transient ureteral...Full Text Available
Tumour hypoxia represents a significant challenge to the curability of human tumours leading to treatment resistance and enhanced tumour progression. Tumour hypoxia can be detected by non-invasive and...Full Text Available
Hypercalcitoninemia has frequently been reported as a marker for medullary thyroid carcinoma. Currently, calcitonin measurements are mostly useful in the evaluation of tumor size and progression, and...Full Text Available
The rapidly emerging science of epigenetics and epigenomic medicine promises to reveal novel insights into the susceptibility to and the onset and progression of epileptic disorders. Epigenetic...Full Text Available
Jan 22, 2011 ... dc.description.abstract, The progress in the development of a surface analysis tool based on the excitation of characteristic luminescence ...
tions, final noise-power spectral density measurements were made. These measurements of the noise-power spectral density were not the desired phase- noise ...
In 2005, the American Medical Informatics Association undertook a set of activities relating to clinical decision support (CDS), with support from the office of the national coordinator and the Agency...Full Text Available
Aging can be defined as a progressive decline in physiological efficiency regulated by an extremely complex multifactorial process. The genetic makeup of an individual appears to dictate this rate...Full Text Available
BackgroundFunction exertion of specific proteins are key factors in disease progression, thus the systematical identification of those specific proteins is a prerequisite to understand...Full Text Available
We present a laser spectroscopic approach for measuring the charge radius of the halo nucleus {sup 11}Li and report on recent progress in the development of the experimental apparatus.
A model of weightlessness in which the hindlimbs of rats are elevated by their tails at a 40 degrees angle to unload the hindlimbs while maintaining normal weight bearing on the forelimbs has been used to simulate certain conditions of space flight. When we used this model in growing rats, we found that growth in bone weight ceased by 1 week in the hindlimbs and lumbar vertebrae, whereas growth in bone weight in the forelimbs and cervical vertebrae remained unaffected. Within 2 weeks, however, the accretion of bone weight in the hindlimbs and lumbar vertebrae returned to normal despite continued skeletal unloading. Since bone weight in the growing rat is primarily determined by bone formation (bone resorption is modest), we investigated the effects of selective skeletal unloading on bone formation during 2 weeks of hindlimb elevation using radioisotope incorporation (with /sup 45/Ca and (/sup 3/H)proline) and histomorphometry (with tetracycline labeling). The ...
Except nuclear industry, diverse structures (hospitals, of research or manufacturers) can have appeal to the use of radioisotopes conditioned under unsealed shape. Such practices lead to tolerate releases in environment in the respect of a statutory device. So the collective network can contain radioisotopes the future of which is going to depend partially on the cleaning applied to waste water. This study through the analysis of a concrete case, has for objective to inform about the future of gamma radioelements present in waste water treated by a wastewater treatment plant. The contamination of the network is essentially due to Tc{sup 99} and I{sup 131}, radioelements present whatever the working day and the hour considered. The total estimated in-load for a day is important, of the order of 4000 MBq for Tc{sup 99} and 15 to 300 MBq for I{sup 131}. The assessment of cleaning of the station shows that this one plays a role towards this ...
The first Russian reprocessing facility, known as RT-1 (located at PA-Mayak in Ural region) was started on the radiochemical plant base in 1977. Nowadays RT-1 is the sole operating reprocessing plant in Russia. The main features of RT-1 is its broad spectrum of reprocessing spent nuclear fuels (SNF). The following spent fuel types are reprocessed: -) SNF from PWR reactors (WWER-440) and FB reactor (BN-600); -) SNF of transport ship reactors; -) production reactors SNF; -) research reactor spent nuclear fuel. The world-known technological processes are used at RT-1, but there are the following distinctive features. First, the universality of the three technological lines which allows not only the reprocessing of various SNF kinds, but also to implement the combined reprocessing of some types of them. Secondly, extraction of neptunium during SNF reprocessing which is used to implement its separate storage and for radioisotope production. Thirdly, target enrichment of ...
The first Russian reprocessing facility, known as RT-1 (located at PA-Mayak in Ural region) was started on the radiochemical plant base in 1977. Nowadays RT-1 is the sole operating reprocessing plant in Russia. The main features of RT-1 is its broad spectrum of reprocessing spent nuclear fuels (SNF). The following spent fuel types are reprocessed: -) SNF from PWR reactors (WWER-440) and FB reactor (BN-600); -) SNF of transport ship reactors; -) production reactors SNF; -) research reactor spent nuclear fuel. The world-known technological processes are used at RT-1, but there are the following distinctive features. First, the universality of the three technological lines which allows not only the reprocessing of various SNF kinds, but also to implement the combined reprocessing of some types of them. Secondly, extraction of neptunium during SNF reprocessing which is used to implement its separate storage and for radioisotope production. Thirdly, target enrichment of ...
The General-Purpose Heat Source (GPHS), an improved radioisotope heat source, employs a unique thermal insulation material, carbon-bonded carbon fiber (CBCF), to protect the fuel capsule and to help achieve the highest possible specific power. The CBCF insulation is made from chopped rayon fiber about 10 ..mu..m in diameter and 250 ..mu..m long, which is carbonized and bonded with phenolic resin particles. The CBCF shapes, both tubes and plates, are formed in a multiple molding facility by vacuum molding a water slurry of the carbonized chopped-rayon fiber (54 wt %) and phenolic resin (46 wt %). The molded shapes are subsequently dried and cured. Final carbonization of the resin is at 1600/sup 0/C. Machining to close tolerances (+-0.08 mm) is accomplished by conventional tooling and fixturing. The resulting material is an excellent lightweight insulation with a nominal density of 0.2 Mg/m/sup 3/ and a thermal conductivity of 0.24 W(m.K) in vacuum at 2000/sup 0/C. ...
The progress report for the Theoretical Physics Division of the United Kingdom Atomic Energy Authority, Harwell, 1985/6 is presented. The Division's research programme is divided into four sections - i) nuclear power (fuels, inspection and safety aspects), ii) radioactive waste management, iii) underlying research, and iv) non-nuclear contract research. The report contains a description of the research work carried out on these four topics in the above period. (U.K.).
Statistical data on the world energy consumption are given to illustrate the following situation in 2001: the deceleration of the world economic growth and the high prices of oil slowed down the progression of the energy consumption: 0,7 % in 2001; stagnation of the gas and oil consumption and strong progression for coal and electricity in 2001; the deceleration for gas marks a strong inflection compared to the past trends. (A.L.B.)
This report summarizes the objectives, background, technical progress, and status of ANL electric vehicle battery R&D tasks for DOE-EHP during the period of January 1 through March 31, 1991. The work is organized into the following six task areas: Project management; battery systems technology; lithium/sulfide batteries; advanced sodium/metal chloride battery; aqueous batteries; and EV Battery performance/life evaluation.
Brief summaries are given of research carried out in the following areas: absorption spectroscopy of titanium, niobium, and molybdenum in uranium alloys; atomic absorption spectroscopy of selenium in stainless steel, computer program improvements for spectrophotometer control, and detection of beryllium in stack gases; electrolysis for inactivation of bacteria in cooling-tower water; improved solvent analysis by gas chromatography; sequential radionuclide separation for various sample matrices; progress on an electron microprobe analyzer; and miscellaneous projects.
The objective of Phase IV of the contract is to design a conceptual flue gas treating unit based on the fluidized-bed Copper Oxide (FBCO) process for a new coal-fired 500 MW(e) power plant. A technical and economic evaluation of the FBCO process, based on the conceptual design, will also be completed. Progress is described.
This paper traces the development and progress of magnetic suspension systems and magnetic bearings in the USSR. The paper describes magnetic bearings for turbomachines, magnetic suspension systems for vibration isolation, some special measuring devices, wind tunnels, and other applications. The design, principles of operation, and dynamic characteristics of the system are presented.
During the past 3 years, progress was made in elucidating the excited state structures of Pt(diimine)(dithiolate) complexes, while more recent efforts focused on the photochemistry of these complexes and electronic structure of other dithiolate systems. A carbonyl-Ir-maleonitrile dithiolate complex is also studied.
This is a progress report from the Health and Safety Research Division of Oak Ridge National Laboratory. Information is presented in the following sections: Assessment Technology, Biological and Radiation Physics, Chemical Physics, Biomedical and Environmental Information Analysis, Risk Analysis, Center for Risk Management, Associate Laboratories for Excellence in Radiation Technology (ALERT), and Contributions to National and Lead Laboratory Programs and Assignments--Environmental Restoration.
A state-by-state review of major geothermal-development activities during 1982 is presented. It also inlcudes a summary of recent drilling and exploration efforts and the results of the 1982 leasing program. Two complementary sections feature an update of geothermal direct-use applications and a site-by-site summary of US geothermal electric-power development.
The reactor core of TAPP-3 and 4 is divided into 14 power zones for spatial power control. Corresponding to each zone is a light water zonal compartment. The 14 ZCCs are located in two radial planes, each containing 7 ZCCs. For each zone, power measurement is carried out using three cobalt Self Powered Neutron Detectors (SPNDs) at appropriate locations close to the respective ZCC. Since the zone power as obtained by the true average of the healthy zone control detector (ZCD) readings belonging to a particular zone may not correspond to its actual power because these 3 detectors per zone, measure only point fluxes but the zone extends over a large core region. Therefore accurate estimation of zone power calibration factors is required to estimate the zone powers and also to provide effective spatial power control to avoid the xenon induced spatial power oscillations in large PHWRs like 540 MWe Reactor. This accurate calculation of zone power is carried out by FMS ...
Cerebral blood flow (CBF) and cerebrovascular reserve capacity (CRC) were measured by stable xenon computerized tomography (Xe-CT) and acetazolamide test in 15 patients with cerebrovascular disease before and after extracranial-intracranial (EC-IC) bypass surgery for minor stroke, reversible ischemic neurological deficit or transient ischemic attack. All had angiographically shown occlusive lesions of the major arterial trunk. In the present series, global analysis showed that the bypass did not increase the resting rCBF, but did increase the rCRC. We divided the patients into four groups according to the preoperative resting rCBF and rCRC. All 3 patients with normal resting rCBF and reduced rCRC showed postoperative improvement of rCRC. Of 6 patients with reduced CBF and reduced CRC, three had postoperative increase in resting CBF and four had increased CRC. One of two patients with reduced CBF and normal CRC showed only an increase in CRC. We propose that reduced ...
Our institute has been investigating laser-produced tin, lithium and xenon plasma for extreme ultraviolet (EUV) light source of EUV lithography system, and found the highest conversion efficiency of 3% at 13.5 nm in 2% bandwidth. In the present paper, we introduce fabrication methods of density-controlled tin targets to generate relatively monochromatic EUV, and higher conversion efficiency than bulk tin. The first method is the nano-template method, where liquid tin solution was immersed into a polymer film with monodispersed size nano-particle. The density can be controlled by tin concentration of the solution. The target can be classified into mass-limited target. We have shown a tendency of monochromatic EUV emission around 13.5 nm with decreasing of tin density. The intensity was higher than tin foil with bulk density. The tendency has a merit to mitigate heat effect of the first EUV mirror. The fabrication method has another merit to control not only density ...
Our institute has been investigating laser-produced tin, lithium and xenon plasma for extreme ultraviolet (EUV) light source of EUV lithography system, and found the highest conversion efficiency of 3% at 13.5 nm in 2% bandwidth. In the present paper, we introduce fabrication methods of density-controlled tin targets to generate relatively monochromatic EUV, and higher conversion efficiency than bulk tin. The first method is the nano-template method, where liquid tin solution was immersed into a polymer film with monodispersed size nano-particle. The density can be controlled by tin concentration of the solution. The target can be classified into mass-limited target. We have shown a tendency of monochromatic EUV emission around 13.5 nm with decreasing of tin density. The intensity was higher than tin foil with bulk density. The tendency has a merit to mitigate heat effect of the first EUV mirror. The fabrication method has another merit to control not only density ...
An RF plasma sputter type heavy negative ion source, which can deliver mA-class negative ion beams (12.1 mA, 1.6 mA and 2.3 mA for Cu{sup -}, C{sup -} and C{sub 2}{sup -} currents, respectively) in dc-mode operation, has been developed. In ion source, a dense plasma of 10{sup 11} cm{sup -3} order was generated in the xenon gas pressure of 10{sup -3}-10{sup -2} Pa with an rf (13.56 MHz) power of 200 - 300 W by using an RF coil, and a relatively large sputtering target of 42 mm in diameter was used. As for intense negative ion beams of silicon or boron which are important dopants for semiconductor fabrication, negative ion extraction properties of the negative ion source was investigated. The extracted total negative ion currents of 4.4 mA for a silicon target and 2.8 mA for a LaB{sub 6} target were obtained after electrons were eliminated by magnetic field near the extraction hole. From results of mass-analysis, it was found that Si{sup -} current of 3.8 mA and ...
Full text: In the upper layers of the Earth's atmosphere, molecular nitrogen absorbs the extreme ultraviolet (XUV) solar radiation. The absorption is associated with dipole-allowed excitation of states of singlet ungerade symmetry ("1#SIGMA#"+_u and "1#PI#_u), which are known to undergo predissociation due to coupling with a mainfold of "1#PI#_u states. We determined new N_2 isotopic lifetimes of many "1#SIGMA#"+_u and "1#PI#_u states via line broadening measurements in the frequency domain. Ultrahigh resolution XUV + UV ionization spectra were recorded (bandwidth #approx# 250 MHz, resolving power 10"7), from which the natural linewidth, i.e. lifetime, was determined. These lifetimes provide new information about the predissociation of the singlet ungerade states in N_2. Tunable narrowband XUV radiation was produced by successively pulsed amplification of cw dye laser radiation, frequency doubling the pulsed visible laser beam into the UV and frequency tripling the UV in a ...
The adsorption equilibria of Kr, Xe and N{sub 2}, which are constituents of the off-gas from nuclear reprocessing processes, on representative adsorbents (Molecular Sieve 5A (MS5A) and activated charcoal) were studied. Adsorption experiments were conducted in the temperature range of 77 to 323 K using a packed bed column. The adsorption isotherms for the activated charcoal adsorbent were successfully correlated by the vacancy solution model. The adsorption isotherms for the MS5A adsorbent were properly correlated by the Langmuir model and the vacancy solution model. The adsorption experiments for the binary component systems (Kr-Xe, Kr-N{sub 2} systems) were also performed, and the results suggest that the coexistence of Xe greatly inhibits the adsorption of Kr. The coexistence of large amounts of N{sub 2} was also found to inhibit the adsorption of Kr. The experimental results for the adsorption equilibrium of binary component systems on the activated charcoal adsorbent were well ...
Absorption of the excimer laser radiations of 193-nm argon fluorine and 308-nm xenon chloride in balanced salt solution, sodium hyaluronate, and human cadaver eyes was measured. The absorption of these materials as considerably different for the two wavelengths; we found that 308-nm light experienced much less absorption than the 193-nm light. The extinction coefficient (k) for 308 nm was k = 0.19/cm for balanced salt solution and k = 0.22/cm for sodium hyaluronate. In contrast to this, the extinction coefficient for 193 nm was k = 140/cm for balanced salt solution and k = 540/cm for sodium hyaluronate. Two 1-day-old human phakic cadaver eyes showed complete absorption with both wavelengths. Using aphakic eyes, incomplete absorption was noted at the posterior pole with 308 nm and complete absorption was noted with 193 nm. The extinction in the anterior part of aphakic eyes (the first 6 mm) was 4.2/cm for 308 nm, meaning that the intensity of the light is reduced by ...
Lisy ME, Jarvis KB, DelBello MP, Mills NP, Weber WA, Fleck D, Strakowski SM, Adler CM. Progressive neurostructural changes in adolescent and adult patients with bipolar disorder.-Bipolar Disord 2011: 13: 396-405. 2011 The Authors.-Journal compilation 2011 John Wiley & Sons A/S. Objectives:- Several lines of evidence suggest that bipolar disorder is associated with progressive changes in gray matter volume (GMV), particularly in brain structures involved in emotional regulation and expression. The majority of these studies however, have been cross-sectional in nature. In this study we compared baseline and follow-up scans in groups of bipolar disorder and healthy subjects. We hypothesized bipolar disorder subjects would demonstrate significant GMV changes over time. Methods:- A total of 58 ...
This progress report concerns work completed or initiated since our last report in October of 1980. We have performed experiments in two major areas: photodissociation of organic cations to study the competition between isomerization and fragmentation; and, low energy proton transfer reactions of HCO"+ with selected neutrals. The former area provides a sideline to our combustion studies of proton transfer in hydrocarbon flames, but the question of energy transfer in highly excited gas phase ions impacts directly upon questions closely related to the fate of ions in combustion. The latter area, currently in progress, focuses upon the dynamics of biomolecular reactions of direct relevance to combustion.
The development of comfort in buildings throughout the centuries was influenced by the demand for progress, wealth and innovation in various respects. At present, it seems that progress may only be possible by taking into account the environment and creating methods of reducing further damage to the environment. The innovative feature of future progress my be reducing the impact on the environment from human and building activities by using appropriate technology. As it is impossible to build without any impact on the environment and this is likely to be so in the future, the objective is and will be to find solutions for buildings which are more compatible with the environment. The objective is to demonstrate that it is viable to design buildings with minimized impact on the environment, while still maintaining appropriate comfort levels.
After the LEP dismantling Phase the Cooling and Ventilation Group has started the LHC construction work. Year 2001 through to 2004 will certainly be the most important period of activity for the CV group in the erection phase The author will report on the current works that are in progress on the different LHC Points distinguishing between the Ventilation and the Water Cooling installations. The Ventilation work completed in the new surface buildings in Points 1, 4,5,6 and 8. The work for the Cooling plants comprehend to the pumping stations, the cooling towers and the chilled water production stations in Points 1 and 5, For all of these activities, an updated report of the progress the work, the planning and of the expenses are given. Finally, a brief overview of the future activities is presented.
The Cooling and Ventilation Group has started the LHC construction work in September 1999 and will get into full activity when LEP will be stopped and dismantled: in total 12 major contracts for an amount of about 120 MCHF will be established to build the needed installations for the LHC. The author will report on the current works that are in progress on the different LEP Points distinguishing between the Ventilation and the Water Cooling installations. The Ventilation work, completed in the new surface buildings in Points 18, is currently held in Points 4 and 5. Point 1 will follow in the near future. The work for the Cooling plants comprehend the pumping stations, the cooling towers and the chilled water production stations in Points 1 and 5, the buried pipes in Points 1 and 4. For all of these activities, an updated report of the progress of the work, of the planning and of the expenses is given. Finally, a short overview of the future ...
...comAbstract: Hepatocellular carcinoma (HCC), once thought to be a rare tumor in North America, is a rapidly increasing type of cancer in recent years in the United States. Current treatment modalities to halt the disease progression are only marginally effective. The mainstay treatment ...In addition, NM was shown to down-regulate urokinase plasminogen activator (by fibrin zymography) and up-regulate tissue inhibitors of metalloproteinases (by reverse zymography) in another HCC cell line, Sk-Hep-1. MMP-2 and MMP-9 activities were further modulated by cytokines, inducers and inhibitors, including NM. In ... Our results suggest that NM is an excellent candidate for therapeutic use in the treatment HCC by inhibiting critical parameters in cancer development and progression, such as proliferation, invasion and metastasis, and by inducing apoptosis. Last update: 2 September 2011 JavaScript seems ...
Excitation functions for {sup 201}Pb, {sup 202m}Pb, {sup 203}Pb and {sup 204m}Pb radionuclides which are formed via proton induced reactions with natural thallium target have been measured from their respective threshold (E{sub thr}) to 27.5 MeV using activation technique. Natural copper foils were used to monitor the cyclotron beam. The integral yields (MBq/{mu}A h) of the produced radionuclides were calculated from the measured excitation functions. The optimum proton energy range for the production of {sup 203}Pb with low amount of impurities is (16-10 MeV) after 5 h of EOB. The experimental cross-sections for {sup nat}Tl(p,xn) reactions were compared with the cross-sections recommended by the IAEA and with earlier published data when it was possible. (orig.)
The Waste Sampling and Characterization Facility (WSCF) complex consists of the main structure (WSCF) and four support structures located in the 600 Area of the Hanford site east of the 200 West area and south of the Hanford Meterology Station. WSCF is to be used for low level sample analysis, less than 2 mRem. The Laboratory features state-of-the-art analytical and low level radiological counting equipment for gaseous, soil, and liquid sample analysis. In particular, this facility is to be used to perform Resource Conservation and Recovery Act (RCRA) of 1976 and Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) of 1980 sample analysis in accordance with U.S. Environmental Protection Agency Protocols, room air and stack monitoring sample analysis, waste water treatment process support, and contractor laboratory quality assurance checks. The samples to be analyzed contain very low concentrations of radioisotopes. The main reason that ...
The thermal-neutron capture cross section (#sigma#_0_,_g) and the resonance integral (I_0_,_g) leading to the ground state of "2"4"2Am were measured by an activation method for neutron capture by "2"4"1Am. A method with gadolinium, which was similar to the cadmium difference method, was used to measure the cross section #sigma#_0_,_g with attention to resonances of "2"4"1Am. Americium chloride samples containing "2"4"1Am radioisotope were irradiated for 68 h in the long-irradiation plug of the Kyoto University Research Reactor, KUR. Wires of Co/Al and Au/Al alloys were used as monitors to determine thermal-neutron fluxes and epithermal Westcott's indexes at the irradiation positions. An #alpha#-ray spectrometer was used to measure the activity ratios of "2"4"2Cm to "2"4"1Am. On the basis of Westcott's convention, the #sigma#_0_,_g and I_0_,_g values were determined as 628#+-#22 b and 3.5#+-#0.3 kb, respectively. (author)
Radioactive waste is generally classified on the basis of how much radiation and the type of radiation it emits as well as the length of time over which it will continue to emit radiation. Many activities dealing with radioactive materials produce nuclear wastes, including civilian nuclear power programs (nuclear Power plant operations and nuclear fuel-cycle activities), defense nuclear programs (nuclear weapons production, naval nuclear reactor programs, and related R and D), and industrial and institutional activities (scientific research, medical operations, and other industrial uses of Radioisotopic sources or Radio chemicals). To minimize the potential adverse health and environment impacts to people and other systems including of animals, plant and etc, during the entire lifetime of the radionuclides involved, nuclear waste must be carefully and properly managed. The scope of nuclear - waste management encompasses generation, processing (treatment and ...
Ionizing radiation, mainly in the form of #gamma#-rays from the radioisotope cobalt 60, is being used increasingly for the inactivation of contaminants in cosmetic and toiletry preparations. The treatment is applied to the product in its final pack, and therefore, it is important to recognize that the properties of the packaging materials could be affected, particularly if high radiation doses are used. The stability of a wide range of materials is discussed. The nature and extent of chemical and physical changes in plastics very much depends on the presence of antioxidants and other additives, and on the environmental conditions during irradiation. Some useful information is available from research into the use of radiation for the preservation of food - many films and laminates have been cleared for use in the United States. The low radiation doses used for the control of contaminants in cosmetic products are quite unlikely to cause changes in packaging materials ...
The level of assimilation of dietary iron is believed to have an important influence on iron status. To examine the effect of enhancing the availability of dietary iron on iron balance, 17 adult volunteer subjects were given 2 g of ascorbic acid daily with meals for 16 weeks. Serum ferritin levels before and after the study averaged 46 and 43 micrograms/L, respectively, indicating a negligible effect on iron stores. When vitamin C supplementation was continued for an additional 20 months in five iron-replete and four iron-deficient subjects, serum ferritin determinations again failed to indicate any significant effect of the vitamin C on iron reserves. These findings were not explained by intestinal adaptation to the enhancing effect of the vitamin, because radioisotopic measurements of nonheme iron absorption showed no reduction in the enhancing effect of 1 g of ascorbic acid after four months of megadoses of vitamin C. It is concluded that altering the ...
An examination of chemical and radiological characteristics of RI organic liquid waste, wet oxidation by Fenton reaction and decomposition liquid waste treatment process were studied. These items will be applied to develop the equipment of wet oxidation and decomposition liquid waste treatment mixed processes for the safe treatment of RI organic liquid waste which is consisted of organic solvents such as toluene, alcohol and acetone. Two types of toluene solutions were selected as a candidate decomposition material. As for the first type, the concentration of toluene was above 20 vol percent. As for the second type, the solubility of toluene was considered. The decomposition ration by Fenton reaction was above 95 percent for both of them. From the adsorption equilibrium tests, a -Na{sup +} substituted/acid treated activated carbon and Zeocarbon mixed adsorbent was selected for the fixed adsorption column. This mixed adsorbent will be used to obtain the basic design data of liquid waste ...
Full text.Surficial sediment samples were collected from seventeen springs distributed all over Lebanon (east, west, north and south). Concentrations of metals Ca, Fe, Mn, Ni, Cu, Cr, Zn and Pb were determined by energy dispersive x-ray fluorescence technique. Irradiation was done by the radioisotope source Cd-109 and the detection by an EG and G Si(Li) detector. These analysis was done in attempt to assess the impact of anthropogenic sources on ground water quality. Metals concentration in sediment were found to be (Ca:0.05-47%, Fe:0.24-4.2%, Cr:
A radiochemical charged particle activation procedure for production and separation of carrier free {sup 52,56}Mn, {sup 55,56,58}Co and {sup 56,57}Ni has been developed. The radioisotopes produced on bombardment of an iron foil target with a 40 MeV {alpha}-particle beam through the nuclear reactions, Fe({alpha}, {alpha}pxn){sup 52,56}Mn, Fe({alpha}, pxn){sup 55,56,58}Co and Fe({alpha}, nx){sup 56,57}Ni, have been separated by LLX. The target element and the activation products have been sequentially separated from an HCl medium using diethylether and the liquid anion exchanger, TIOA, as extractants. Extent of separation and purity of the carrier free radiotracers at different stages of their LLX separation have been verified by taking recourse to {gamma}-ray spectrometry. (Author).
Heavy ion irradiation on tantalum metal target with 57 MeV "1"1B"4"+ leads to the production of no-carrier-added radioisotopes of platinum, "1"8"7","1"8"8Pt and iridium, "1"8"7","1"8"8Ir in the matrix, which have been effectively separated from the bulk target and from each other with suitable anion exchangers employing liquid-liquid extraction (LLX). Also "1"8"8","1"8"9Pt and "1"8"8","1"8"9Ir radionuclides have been produced, from their short-lived precursors "1"8"8","1"8"9Au, in "1"2C"6"+ irradiated tantalum matrix. Gamma-spectroscopy has been utilised to determine the production, extent of separation and purity of the radiotracers at different stages of the experiment. (orig.)
Understanding risks from exposures to carcinogens and other chemicals depends upon measurement of their dose to target tissues and their reactivity with critical macromolecules. The authors have used AMS detection of radio-isotopes to assess doses and reactivities at low, environmentally relevant doses. Several biomedical investigations show the effectiveness of quantification of biologically important events at extremely high sensitivity with AMS. Specifically, they have measured the addition of environmental carcinogens such as 2-amino-3,8-dimethylimidazo[4,5-f]-quinoaxaline (MelQx), a chemical found in cooked food, to DNA at concentrations relevant to human exposure. Other low level detection problems in biology, such as immunoassay assessment of small environmental chemicals, is being developed with attomole sensitivity. AMS also aids the assessment of genotoxic risks from chemicals by quantifying the binding of labeled chemicals to DNA. The very toxic and ...
For the interests of national security, many scientists who work in the field of nuclear forensic analysis have carried out extensive work in the past on the detection of radioactive material and attributions study, developed a series of scientific and technical means to trace and detect illicit circulation of nuclear materials used to weapons and other radioactive materials which impair public security. All these questions relate to physical, chemical, biological attribution of materials. The nuclear forensic analysis has already become a special, up-to-date sphere of learning. The goal of the study of nuclear forensics is to prevent terrorists from acquiring not only nuclear weapons but also mate- rials that can be used to make such weapons, including radioactive materials for nuclear power plants, and medical radioisotope to and provide us as many clues of environmental links as possible that could help us trace the smuggling path, to answer the following ...
Silver zeolite is used to capture radioiodines from air cleaning systems in some nuclear facilities at the Idaho National Engineering Laboratory. It may become radioactively contaminated and/or poisoned by hydrocarbon vapors, which diminishes its capacity for iodine. Silver zeolite contains up to 38 wt% silver. A pyrometallurgical process was developed to reclaim the silver before disposing of the unserviceable zeolite as a radioactive waste. A flux was formulated to convert the refractory aluminosilicate zeolite structure into a low-melting fluid slag, with Na{sub 2}O added as NAOH instead of Na{sub 2}CO{sub 3} to avoid severe foaming due to CO{sub 2} evolution. A propane-fired furnace was built to smelt 45 kg charges at 1300C in a carbon-bonded silicon carbide crucible. A total of 218 kg (7000 tr oz) of silver was reclaimed from 1050 kg of unserviceable zeolite. Silver recoveries of 97% were achieved, and the radioisotopes were fixed as stable silicates in a ...
Platelet deposition on bovine pericardial-tissue mitral-valve prostheses in 11 dogs was observed noninvasively by use of "1"1"1In-labeled platelets and quantified after sacrifice at one (n . 3), 14 (n . 3), and 30 (n . 5) days postimplantation (300-400 microCi of labeled platelets having been injected 24 hours previously). Thrombosis on the sewing ring and pericardial leaflets at one and 14 days and on the leaflets at 30 days was delineated in scintiphotos. In vitro quantification (% injected dose) indicated that the leaflets, sewing ring, and perivalvular tissue retained 0.904% of labeled platelets at one day postimplantation, 0.198% at 14 days, and 0.040% at 30 days. Platelet half-life was reduced to 38 hours at 21 days postimplantation but returned toward the normal (50 hours) with fibrous ingrowth in the sewing ring. Microembolism in lung and kidney, as measured by tissue/blood radioactivity ratio, also was decreased significantly at 30 days. "1"1"1In-labeled platelets thus provide ...
Techniques for fabricating P-type (Cu,Ag)/sub 2/Se with mesh-type bonds have been developed and are being evaluated for long-term use. In addition, methods for reducing vapor suppression by the use of coatings and/or baffling continue to show gains. The N-type alloy Gd/sub 2/Se/sub 3/ has been shown to be thermally unstable. It undergoes a sluggish cubic-to-orthorhombic phase change below 1000/sup 0/C, with an accompanying degradation in mechanical and thermoelectric properties. Fabrication studies conducted with the (Bi,Sb)/sub 2/(Se,Te)/sub 3/ alloys showed these materials to be sensitive to oxygen contamination if reproducible properties are to be obtained. Preparation of powdered material by explosive techniques was investigated. This technique appears to be useful in preparing homogeneous -325 mesh material, but it does not yield a useful amount of submicron-size powder.
The 3001 Storage Canal is located under portions of Buildings 3001 and 3019 at Oak Ridge National Laboratory (ORNL) and has a capacity of approximately 62,000 gallons of water. The term canal has historically been used to identify this structure, however, the canal is an in-ground reinforced concrete structure satisfying the regulatory definition of a tank. From 1943 through 1963, the canal in Building 3001 was designed to be an integral part of the system for handling irradiated fuel from the Oak Ridge Graphite Reactor. Because one of the main initial purposes of the reactor was to produce plutonium for the chemical processing pilot plant in Building 3019, the canal was designed to be the connecting link between the reactor and the pilot plant. During the war years, natural uranium slugs were irradiated in the reactor and then pushed out of the graphite matrix into the system of diversion plates and chutes which directed the fuel into the deep pit of the canal. After shutdown of the ...
In nuclear power plant Paks, Hungary, alkaline oxidative (NaOH, KMnO_4, H_2O) and acidic reductive (citric- and oxalic acid, water) liquids are using for the decontamination of primary circuit equipment (main liquid circulating pumps, steam generators, pipelines etc). The above mentioned decontamination liquids are containing "1"1"0"mAg, "9"5Nb, "5"4Mn, "5"8 Co, "6"0Co, "5"1 Cr, "1"2"4 Sb radioisotopes, summarized radioactivity is between 10"3-8x10"4 kBq/dm"3 liquid. The decontamination liquid can be cleaned with reactive adsorption (active carbon) and ion-exchange process at elevated temperature (333-368 K) in multilayered columns. After purification the summarized radioactivity for "5"4Mn, "6"0Co, and "1"1"0"mAg are in the outlet liquid below 1 kBq/dm"3. Decontamination factor DF#approx =#10"3-10"4, volumetric reduction factor VRF#approx =#50-500.
Water quality of the Citarum River and the Jatiluhur Reservoir in Indonesia was evaluated using C-14 radioisotope. A close relationship between the abiotic (physical and chemical) and the biotic (algal growth potential, primary productivity, chlorophylla and diversity index of planktonic and benthic macroinvertebrate) parameters was obtained. Algal growth potential to abiotic parameters relationship has the highest correlation coefficient and can be used as a pollution indicator. The other biotic parameters do not show clear relationship with the abiotic parameters. The Citarum water quality is the lowest in those locations which receive human and industrial waste from Bandung and its environment. This water cannot be used for drinking purposes and fishery. The water quality in other locations of the river, however, meets the criteria for agriculture. Agricultural waste does not show any drastic effect on the water quality profile due to non-polluted ...
The authors present arguments against nuclear energy and pro renewable energy sources. Thus, the water used in Uranium mining and primary ore processing becomes contaminated in long lived radioisotopes and so a threat for local ecosystems and communities. Then, during the fabrication, enrichment, and handling of nuclear fuel the workers are exposed to radiations and dangerous accidental radioactive leaks can occur. But, by far, the most menacing aspect of nuclear power exploitation remains the human errors in operating the nuclear plants which can result in major accidents like that from Chernobyl which spread radioactivity all over the Europe. The equipment used in nuclear facilities which is highly contaminated as well as the burned fuel implies transportation and long term storage which also present high risks. The major advantage of the nuclear energy consists in its very low environment impact and its null contribution to the greenhouse effect. In contrast, ...
The measurements of the L X-ray intensity ratio I(L?)/I(L?), I(L?)/I(L?), I(L?)/I(L?), I(L?)/I(L?) and I(L?)/I(L?) for elements Dy, Ho, Yb, W, Hg, Tl and Pb were experimentally determined both by photon excitation, in which 59.5 keV ?-rays from a filtered radioisotope 241Am was used, and by the radioactive decay of 160Tb, 160Er, 173Lu, 182Re, 201Tl, 203Pb and 207Bi. L X-rays emitted by samples were counted by a Si(Li) detector with resolution 160 eV at 5.9 keV. Obtained values were compared with the calculated theoretical values. Theoretical values of the I(L?/L?), I(L?/L?), I(L?/L?), I(L?/L?) and I(L?/L?) intensity ratios were calculated using theoretically tabulated values of subshell photoionization cross-section, fluorescence yield, fractional X-ray emission rates, Coster-Kronig transition probabilities. It was observed that present values agree with previous theoretical and other available experimental results.
64Cu (T1/2=12.7h, ?- decay: 40%, ?+ decay: 19%, E.C. decay: 41%) is one of the most useful radioisotope in the nuclear medicine due to its multiple decay mode and the intermediate half-life. Several nuclear reaction, i.e., 64Ni(p,n)64Cu, 68Zn(p,?n)64Cu and 64Ni(d,2n)64Cu have been investigated for production. The highest could be obtained with proton irradiation on the enriched 64Ni target. For mass and routine production, the 64Ni target fabrication using electroplating, the reliable chemical separation of 64Cu from the irradiated 64Ni target and the effective recovery process for the recycling of very expensive enriched material ($20,000/g) and so forth are absolutely necessary to be established. In this work, we report our mass production method of 64Cu with 64Ni and Cyclone-30 accelerator
The present volume on energy and the environment discusses space power requirements, space power systems, space power systems hardware, space radioisotope systems, space solar arrays, space solar cells, space station power, and terrestrial applications of aerospace technology. Attention is given to NASA future space power requirements and issues, the design of a battery charger for the NASA EOS Space Platform, in situ carbon dioxide fixation on Mars, and a preliminary design update of the CRAF/Cassini Power Subsystem. Topics addressed include concentrator testing using projected images, solar power satellites and demonstraton platforms from nonterrestrial materials, a mass sensitivity analysis of lunar orbiting beam power systems, and a power-beaming-based infrastructure for space power. Also discussed are fiber-optic sensors for aerospace electrical measurements, the preliminary design of a mobile lunar power supply, advanced power systems for EOS, and Air Force ...
The alpha emitter plutonium-238 ("2"3"8Pu), which is produced in uranium-fueled, light-water reactors, is used as a thermoelectric power source for space applications. Inhalation of a mixed oxide form of Pu is the most likely mode of exposure of workers and the general public. Occupational exposures to "2"3"8PuO_2 have occurred in association with the fabrication of radioisotope thermoelectric generators. Organs and tissue at risk for deterministic and stochastic effects of "2"3"8Pu-alpha irradiation include the lung, liver, skeleton, and lymphatic tissue. Little has been reported about the effects of inhaled "2"3"8PuO_2 on peripheral blood cell counts in humans. The purpose of this study was to investigate hematological responses after a single inhalation exposure of Beagle dogs to alpha-emitting "2"3"8PuO_2 particles and to extrapolate results to humans.
The utilization of 14.6-min "1"0"1Mo and 25-min "1"3"1Te for the determination of molybdenum and tellurium in biological materials by neutron activation analysis is described for the first time. Radioisotopes were separated from the samples activated in a thermal neutron flux of about 10"1"4 n cm"-"2s"-"1. The radiochemical procedure for molybdenum involves extraction of Mo"6"+ from 6 M HCl into diethylether, re-extraction into water, precipitation as oxinate, and measurement of the gamma activity of "1"0"1Tc. The tellurium was separated by reduction to the element with SO_2 in 3 M HCl, dissolution in HNO_3, and reprecipitation as the element for the measurement of radioactivity. The sensitivity was estimated at ca. 10 ng at the level of confidence of 95%. The methods were tested by analyzing NBS-standard Bovine Liver and Orchard Leaves for molybdenum; the concentrations found were 3.2 +- 0.1 #mu#g g"-"1 and 300 +- 60 ng g"-"1, respectively. The tellurium content ...
There is an increasing interest in using radioisotopes of rare earth elements for internal radiotherapy and for imaging in nuclear medicine. {sup 177}Lu is one of the promising radionuclides. This article reports on the first measurements of the excitation function for the production of {sup 177}Lu with proton-beam energies up to 17 MeV on natural hafnium targets. The experimental cross sections for the reaction {sup nat}Hf(p,x){sup 177}Lu were obtained by the activation of a stacked-foil target and subsequent gamma spectrometry. Theoretical cross sections were calculated up to 35 MeV with the EMPIRE nuclear reaction model code. The measured and calculated cross sections were used for deriving the thick-target yields and for estimating the production of other nuclides than {sup 177}Lu. Measured production cross sections of {sup 175,176,177,178}Ta on the same target are also presented.
There is an increasing interest in using radioisotopes of rare earth elements for internal radiotherapy and for imaging in nuclear medicine. "1"7"7Lu is one of the promising radionuclides. This article reports on the first measurements of the excitation function for the production of "1"7"7Lu with proton-beam energies up to 17 MeV on natural hafnium targets. The experimental cross sections for the reaction "n"a"tHf(p,x)"1"7"7Lu were obtained by the activation of a stacked-foil target and subsequent gamma spectrometry. Theoretical cross sections were calculated up to 35 MeV with the EMPIRE nuclear reaction model code. The measured and calculated cross sections were used for deriving the thick-target yields and for estimating the production of other nuclides than "1"7"7Lu. Measured production cross sections of "1"7"5","1"7"6","1"7"7","1"7"8Ta on the same target are also presented.
Cerebral angiography, pneumoencephalography, and radioisotope brain scan with their differing diagnostic abilities have provided the neurologist and neurosurgeon with extremely valuable diagnostic techniques. It is doubtful, however, if any of these now conventional methods had the enormous impact on the practice of neurology that computer assisted axial tomography (C.A.T.) is beginning to have. Here, for the first time, is a test which, without significant risk or discomfort, can demonstrate some normal intracranial (and intraorbital) structures, can demonstrate some normal intracranial pathology and, in many cases, can make the potentially dangerous contrast studies unnecessary. After only a few months experience with C.A.T. in a clinical setting, it has become obvious that there will have to be a reappraisal of the accepted investigative work-up of many conditions. While it is too early to have formulated strict criteria for the use of C.A.T., this paper is an ...
Following the publication (Stenhouse and Baxter, Nature; 267:828 (1977)) of the levels of bomb "1"4C and the residence times of carbon in the human body, excess radiation burdens from this radioisotope are evaluated under the assumption that no radiation dose, however small, can be regarded as entirely harmless biologically. The estimated annual absorbed dose attributable to "1"4C both natural and man-made for 1953-1973 and similar predicted figures for 1975-2025 are shown graphically. The cumulated doses to gonads (over 30 yr) and to bone marrow and bone-lining cells (over 60 yr) and also estimates of the biological damage to reproductive cells from "1"4C #beta#-irradiation (30 yr accumulated dose) are presented. It is concluded from both genetic and somatic considerations, that the potential human radiation burden due to artificially produced "1"4C calculated using the assumptions stated is certainly significant and, therefore, cannot be dismissed. However, ...
Since the radiometric measuring technique was introduced for industrial measuring and control engineering 15 to 20 years ago, the advantages of this technique have become more and more evident and have led to its world-wide application. In the last 15 to 20 years this method has become the standard one in this field. Its major advantages as compared with conventional methods are: contactless measurement; high reliability and accuracy; no mechanically moving parts; and no maintenance required. Despite higher investment costs the application of this method is paid off within a very short time owing to a higher output and the savings in maintenance costs. Some chemo-technical methods can be realized on a grand scale only when radiometric measuring equipment is used - e.g., urea plants, high-pressure polyethylene production. Especially in moisture measurements of blast-furnace coke are the economical advantages significant. Detailed studies have shown that the system pays off within a few ...
Research and development and other activities of the various constituent units of Department of Atomic Energy (DAE) and also of the institution aided by DAE for the year 2005-2006 are reported. The various constituents units of DAE consist of nuclear research centres, nuclear power stations, fuel reprocessing and heavy water plants, nuclear fuel fabrication facilities, electronic and instrumentation production organisations, atomic mineral processing units and other nuclear installations. The activities of DAE cover the whole gamut of nuclear fuel cycle, research and development in nuclear science and reactor technology, applications of radiation and radioisotopes, radiation protection, research and development in front line areas such as robotics, lasers, mathematics and computational sciences. International research collaborations like CERN-DAE collaboration were completed by BARC. These activities are described broadly under: executive summary, nuclear power ...
An aerial radiological survey was conducted over the Department of Energy's Hanford Site near Richland, Washington, during the period 5 July through 26 August 1988. The survey was expanded, and additional flights were conducted to the east of the site and along the banks of the Columbia River down to McNary Dam near Umatilla. The survey was flown at altitude of 61 meters (200 feet) by a helicopter containing 17 liters (eight 2 in. x 4 in. x 16 in.) of sodium iodide detectors. Gamma ray data were collected over the survey area by flying north-south lines spaced 122 meters (400 feet) apart. The processed data indicated that detected radioisotopes and their associated gamma ray exposure rates were generally consistent with those expected from normal background emitters and man-made fission/activation products resulting from activities at the site. External exposure rates were generally 10 microroentgens per hour (#mu#R/h) with some operating areas over 1000 #mu#R/h. ...
Activation has been used for many kinds of useful applications, such as use of the radioisotopes for diagnosis and treatment of cancer, and wear (or corrosion) investigation for using thin layer activation (TLA) technique, etc. But activation also has severe problems for the post-processing of the samples; such as time-loss, inconvenience of sample handling, personal radiation safety, etc. For in-vitro experiments, we observed death of tumor cells by proton irradiation. The use of large activated container material can cause erroneous results in this case. To solve these problems, we studied why the samples were activated and how the level of the activation could be reduced. In proton beam irradiation experiments, the target materials could be defined as the container and sample itself. We could easily reduce activation of container material comparing to activation of sample itself. Therefore, we tried to find less activated container material by irradiating proton ...
The Wolsung-1 CANDU 600 MWe plant is now in operation. This paper provides an update on the design, construction and commissioning progress reported at last year's conference. The accomplishments of the past year are highlighted with emphasis on how the s...
This 2-page fact sheet gives statistics on routine waste generation and projected reduction by waste type, and 1994 pollution prevention and recycling accomplishments at ORNL.
Progress is reported on: radon barrier systems for uranium mill tailings; liner evaluation for uranium mill tailings; revegetation/rock cover for stabilization of inactive U-tailings sites; and application of long-term chemical biobarriers for uranium tailings.
Albeit the considerable progress that has been made both in our understanding of the pathophysiology of acute renal failure (ARF) and in its treatment (continuous renal replacement therapies), the morbidity...Full Text Available
BackgroundHerbivore feeding elicits dramatic increases in defenses, most of which require jasmonate (JA) signaling, and against which specialist herbivores are thought to be better...Full Text Available
This report describes a quality assurance program plan for the Yucca Mountain Project. Aspects of the plan include: document control, equipment maintenance and calibration, process control, audits, computer software, and inspections. (CBS)
In addition to the well documented role of cytokines in mediating tissue-level interactions, it is now clear that matrix macromolecules fulfil a complementary regulatory function. Data highlighted in...Full Text Available
Treatment with sorafenib prolongs both the median survival and time to progression by nearly 3 months in patients with advanced hepatocellular carcinoma. Although the effects of combining sorafenib...Full Text Available
DNA transposons are efficient tools in transgenesis and have therefore become popular in the analysis of the regulatory genome in vertebrates via enhancer trap screens. Here, I discuss recent progress...Full Text Available
This talk summarizes recent progress in top quark physics studies for high energy linear electron-positron colliders as presented at the LCWS2000 Workshop at Fermilab. New results were presented for top pair production at threshold and in the continuum, as well as for top production at #gamma##gamma# colliders.
Motivation: Since database retrieval is a fundamental operation, the measurement of retrieval efficacy is critical to progress in bioinformatics. This article points out some issues with...Full Text Available
PurposeTo date there remains no effective therapy for metastatic melanoma and at the molecular level disease progression remains poorly understood. Recent work by...Full Text Available
The challenge to our profession today is to improve the quality of oral health while overcoming both extrinsic and intrinsic factors which may adversely affect our progress toward this goal. The combined...Full Text Available
Paraquat poisoning in mammals results in a characteristic lung lesion manifested principally as progressive pulmonary fibrosis. Paraquat is actively concentrated into the lung but the site of uptake remains undefined. A method is described for the autoradiographic localization of paraquat in rats. Preliminary evidence for the site of uptake implicates the bronchiol. (author).
The commercial potential of the 17 m, 100 kW Darrieus Vertical Axis Wind Turbine (VAWT) is discussed. Long term testing is in progress. As the first commercially adapted Darrieus turbines built by DOE, the superior cost, structural integrity, and output characteristics demonstrated by the prototypes appear particularly promising.
The progress of laboratory studies on the removal of NO/sub x/ and SO/sub 2/ with zeolite molecular sieves is reported. The trademark of these zeolite molecular sieves is Zeolon. (LK)
Deep brain stimulation of the subthalamic nucleus (STN-DBS) is efficacious in treating the motor symptoms of Parkinson’s disease (PD). However, the impact of STN-DBS on the progression...Full Text Available
Patients with Alport syndrome progressively lose renal function as a result of defective type IV collagen in their glomerular basement membrane. In mice lacking the α3 chain of type IV collagen...Full Text Available
There are 173 three quasiparticle rotational bands, out of which 38 bands display signature splitting and sometimes a signature inversion also. The observed signature splitting is basically due to the higher order Coriolis coupling and calculation based on particle rotor model (PRM) are in progress
Human epidermal growth factor receptor 2 (HER2) is one of the most important prognostic and predictive factors for breast cancer patients. Recently, serum HER2...Full Text Available
AbstractStudies performed to identify early events of ovarian cancer and to establish molecular markers to support early detection and development of chemopreventive regimens have been...Full Text Available
The secreted Bv8 protein has been recently characterized as a regulator of myeloid cell mobilization and a neutrophil-derived mediator of tumor angiogenesis in several xenografts, but its role in tumor...Full Text Available
BackgroundStudies using transthoracic thermodilution have demonstrated increased extravascular lung water (EVLW) measurements attributed to progression of edema and...Full Text Available
The CWDD injector has been shipped to Argonne National Laboratory, installed, and recommissioned. Commissioning progress, operational status, and future plans are reported. Operational experience at ANL is compared with that obtained at Culham.
Systemic chemotherapy has been relatively ineffective in the treatment of malignant brain tumors even though systemic chemotherapy drugs are small molecules that can readily extravasate across the porous...Full Text Available
The Gordon Research Conference (GRC) on ROCK DEFORMATION was held at II Ciocco from 5/19/02 thru 5/24/02. Emphasis was placed on current unpublished research and discussion of the future target areas in this field.
RationalePrevious research has shown that rats exposed perinatally to phencyclidine (PCP) exhibited neuroanatomical abnormalities and altered cognition. In addition...Full Text Available
A 33-year-old man sustained an acute Achilles tendon rupture which was surgically repaired. Early nonweight-bearing range of motion and strengthening of the ankle and the repaired muscle unit was allowed...Full Text Available
The Pde6brd10 (rd10) mouse has a moderate rate of photoreceptor degeneration and serves as a valuable model for human autosomal recessive retinitis pigmentosa...Full Text Available
... based, disease treatment remains promising, the emphasis for stem cell research from the biomedical research community is clear, and ... diagnosis as a novel source of embryos for stem cell research. Repr...
In the past decade, we have witnessed a revolution in osteoporosis diagnosis and therapeutics. This includes enhanced understanding of basic bone biology, recognizing the severe consequences of fractures...Full Text Available
This is a report of surgical treatment of thoracoabdominal aortic aneurysms and aneurysms of the abdominal aorta from which the visceral vessels arise during the 18 year period from April 5, 1960,...Full Text Available
AIM: To investigate the role of metallothionein in colorectal tumours and the possible relation with other factors associated with tumour progression: expression of cathepsin D (CD), CD44, p53, Rb,...Full Text Available
Cervical cancer is known to metastasize primarily by the lymphatic system. Dissemination through lymphatic vessels represents an early step in regional tumor progression, and the presence of lymphatic...Full Text Available
Background. Detection of subjects with early chronic kidney disease (CKD) is important because some will progress up to stage 5 CKD, and most are at high risk of cardiovascular morbidity...Full Text Available
Recognition of HIV-1 ssRNA by TLR7 induces the production of the pro-inflammatory cytokines that may contribute to the systemic immune activation associated with HIV-1 disease progression. Here...Full Text Available
Medical treatment of heroin addiction with methadone and other pharmacotherapies has important benefits for individuals and society. However, regulatory policies have separated this treatment from the...Full Text Available
This chapter summarizes research progress in development of phytoremediation technologies. Some soils have become contaminated by trace elements enough to kill plants, inhibit soil organisms, and/or threaten wildlife, humans or the environment. Traditional remediation by dig and haul methods are v...
During the past 3 years, progress was made in elucidating the excited state structures of Pt(diimine)(dithiolate) complexes, while more recent efforts focused on the photochemistry of these complexes and electronic structure of other dithiolate systems. A carbonyl-Ir-maleonitrile dithiolate complex is also studied.
Idiopathic pulmonary fibrosis (IPF) is a progressive disease with poor survival. The identification of therapeutic targets is essential to improving outcomes. Previous studies found that expression...Full Text Available
Advances in neuroscience have resulted in the development of new diagnostic and therapeutic agents for potential use in the central nervous system (CNS). However, the ability to deliver the...Full Text Available
BackgroundAurora kinases play an essential role in orchestrating chromosome alignment, segregation and cytokinesis during mitotic progression, with both aurora-A and B frequently...Full Text Available
This report discusses: shape coexistence in {sup 184}Pt; nuclear structure of {sup 187}Ir; g-factors of excited states; OLNO-2; and refrigerator development.
BackgroundRetinitis pigmentosa (RP) is characterized by progressive night blindness, visual field loss, altered vascular permeability and loss of central vision. Currently there...Full Text Available
BackgroundAlthough considerable progress has been made in the treatment of chronic kidney disease, compromised quality of life continues to be a significant problem for patients...Full Text Available
Since the inception of blood banking, refinements in laboratory processes have allowed for progressively longer storage times of red blood cells. Whilst advantageous for the logistics of stock management,...Full Text Available
A case of neurocysticercosis with progressive severe neurological symptoms is described. The patient was a Turkish girl aged 4 1/2 years who had experienced intermittent neurological symptoms for two years. Rapid diagnosis and treatment with praziquantel and corticosteroid resulted in complete restitution.
This quarterly update contains information on the National Bioenergy Center Biochemical Platform Integration Project, R&D progress and related activities.
...research and publications and some who are accredited by the British Association of Sport and Exercise Sciences (BASES), which enables them to work with high performance athletes . We care about your progress and welfare. As our recent QAA review noted \\
We performed genome-wide homozygosity mapping in a large consanguineous family from Morocco and mapped the autosomal-recessive nonsyndromic hearing loss (ARNSHL) in this family to the DFNB79...Full Text Available
PurposeRetinitis pigmentosa (RP) is a genetically heterogeneous disorder characterized by progressive loss of vision. The aim of this study was to identify the causative mutations...Full Text Available
BackgroundThe precise mechanisms involved in the initiation and progression of rheumatoid arthritis (RA) are not known. Early stages of RA often have non-specific symptoms, delaying...Full Text Available
Early detection of precancerous tissue has significantly improved survival of most cancers including colorectal cancer (CRC). Animal models designed to study the early stages of cancer are valuable...Full Text Available
Muscular dystrophies (MDs) comprise a group of degenerative muscle disorders characterized by progressive muscle wasting and often premature death. The primary defect common to most MDs involves disruption...Full Text Available
BackgroundThe tumor microenvironment has been described as a critical milieu determining tumor growth and metastases. A pivotal role of metastasis-inducing S100A4 in the development...Full Text Available
Objective is to study the effects of local structure, interatomic forces, and atom size on the mobility of metal atoms in amorphous silica and at the silica surface. EXAFS studies of Zn and Pt in silica are reported. (DLC)
The CKM angle $\\gamma/\\phi_{3}$ had been measured by two B-factories, the PEPII collider for the BaBar experiment and the KEKB collider for the Belle experiments. The present paper reports recent progress in $\\gamma/\\phi_{3}$.
Neuronal death is known to trigger reactive microgliosis. However, little is known regarding the manner by which microglia are activated by injured neurons and how microgliosis participates...Full Text Available
Purpose: Small animal micro-CT imaging is being used increasingly in preclinical biomedical research to provide phenotypic descriptions of genomic models. Most of this imaging is coincident...Full Text Available
Objectives To understand the perspectives of people with severe chronic obstructive pulmonary disease (COPD) as their illness progresses, and of their informal and professional carers,...Full Text Available
A Legionella-like organism, strain 1677-MI-H, was isolated from the bronchoscopy washings of a patient with pneumonia who had a 2-year history of progressive, chronic lymphocytic leukemia. The growth...Full Text Available
The somatic sensory system responds to stimuli of distinct modalities, including touch, pain, itch, and temperature sensitivity. In the past century, great progress has been made in understanding the...Full Text Available
Polycystic kidney disease (PKD) is one of the leading causes of end-stage renal disease in humans and is characterized by progressive cyst formation, renal enlargement, and abnormal tubular development....Full Text Available
As the result of genetic alterations and tumor hypoxia, many cancer cells avidly take up glucose and generate lactate through lactate dehydrogenase A (LDHA), which is encoded by a target gene of c-Myc...Full Text Available
BackgroundClinical studies suggest that local wall shear stress (WSS) patterns modulate the site and the progression of atherosclerotic lesions. Computational fluid dynamics (CFD)...Full Text Available
Mouse models have dramatically improved our understanding of cancer development and tumor biology. However, these models have shown limited efficacy as tractable systems for unbiased genetic...Full Text Available
Dementia with Lewy bodies (DLB) is the second most common cause of degenerative dementia after Alzheimer's disease (AD), and is clinically characterized by the progressive cognitive decline with fluctuations...Full Text Available
Telomerase, a ribonucleoprotein enzyme that maintains telomere length, is crucial for cellular immortalization and cancer progression. Telomerase activity is attributed primarily to the expression of...Full Text Available
The biological accumulation of heavy metals and cesium, strontium, and uranium in plants is discussed. The role of nutrient deficiencies and foliar treatments of manganese and iron compounds is described.
The technical committees of the International Electrotechnical Committee (IEC) play an important part in preparing international standards. In this report the chairman of the Technical Comittee 14 (Power Transformers) describes the present state and the progressive work.
Alternative energy resources such as hydrogen and methane gases are becoming increasingly important for the future economy. A major challenge for using hydrogen is to develop suitable materials to store...Full Text Available
AimTo assess the progression of bronchial reactivity (BR) and incidence of bronchial hyperreactivity (BH), exercise‐induced bronchoconstriction (EIB) and asthma in triathletes...Full Text Available
Stargardt-like macular degeneration (STGD3) is an early onset, autosomal dominant macular degeneration. STGD3 is characterized by a progressive pathology, the loss of central vision, atrophy...Full Text Available
Recently, there has been significant progress in the development of genetically-engineered mouse (GEM) models. By introducing genetic alterations and/or signaling alterations of human pancreatic cancer...Full Text Available
Benign prostatic hyperplasia (BPH) is a complex and progressive disease common in aging men. While associated with bothersome lower urinary tract symptoms, it may also result in additional serious complications...Full Text Available
The Melt Vessel Interaction (MVI) project is concerned with the consequences of the interactions that a core melt, generated during a postulated severe accident in a light water reactor, may have with the pressure vessel. In particular, the issues concerned with the failure of the vessel bottom head are the focus of the research. The specific objectives of the project are to obtain data and develop validated models, which could be applied to prototypic plants, and accident conditions, for resolution of issues related to the melt vessel interactions. The project work has been performed by nine partners having varied responsibility. The work included a large number of experiments, with simulant materials, whose observations and results are employed, respectively, to understand the physical mechanisms and to develop validated models. Applications to the prototypic geometry and conditions have also been performed. This report is volume 1 of the Final Report for the Project, in which a ...
This document is the published result, conclusion, or progress report of research performed by the staff of the U.S. Geological Survey, Fort Collins Science ... ...
Chemoprevention strategies to prevent the development of lung cancer in at-risk individuals are a key component in disease management. In addition to being highly effective, an ideal chemopreventive...Full Text Available
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Concl...
ObjectivesWe examined the expression of Rho Kinase (ROK) isoforms in young and old rabbit’s detrusor smooth muscles (SM) during the progression of short term...Full Text Available
Mutational inactivation of the RB1 tumor suppressor gene initiates retinoblastoma and other human cancers. RB1 protein (pRb) restrains cell proliferation by binding...Full Text Available
A rapid expansion of urban systems, particularly in less-developed countries, pose considerable challenges. Urbanization also provides opportunities for socio-economic progress. Relative contribution...Full Text Available
The earliest clinical evidence of diabetic nephropathy is microalbuminuria. Progression from microalbuminuria to overt nephropathy occurs in 20-40% within a 10-year period with approximately 20% of...Full Text Available
BackgroundChina has had no effective and systematic information system to provide guidance for strengthening PHC (Primary Health Care) or account to citizens on progress. We report...Full Text Available
DNA damage is a threat to genomic integrity in all living organisms. Plants and green algae are particularly susceptible to DNA damage especially that caused by UV light, due to their light dependency...Full Text Available
The hierarchical arrangement of collagen and mineral into bone tissue presumabley maximizes fracture resistance with respect to the predominant strain mode in bone. Thus, the ability of cortical...Full Text Available
The Cordoba and Wolsung projects mark the entry into the international sales arena of the standardized Canadian 600 MWe CANDU-PHW reactor design. The Cordoba station experienced a setback in the early stages when severe inflation in Argentina led to a ren...
Significant progress was made in the May 1990--May 1991 contract period in three primary coal liquefaction research areas: catalysis, structure-reactivity studies, and novel liquefaction processes. A brief summary of the accomplishments in the past year in each of these areas is given.
Myocarditis, often initiated by viral infection, may progress to autoimmune inflammatory heart disease, dilated cardiomyopathy and heart failure. Although cardiac myosin is a dominant autoantigen...Full Text Available
For over 20 years advocates of computer assisted instruction (CAI) have been proclaiming impending revolutionary developments in the educational process, yet progress in acceptance has been slow. This...Full Text Available
Johne disease, caused by Mycobacterium avium, subspecies paratuberculosis (MAP) is becoming increasingly widespread on dairy farms worldwide, due in part, to the absence...Full Text Available
There are many methods to screen for abnormal amounts of proteinuria to identify patients at risk for progression of renal disease, but which method best predicts renal risk is unknown. Here, we analyzed...Full Text Available
DOE is supporting the development of several conversion processes that are currently in the pilot plant stage. Each of these processes is described briefly and information given as to contractor, contract, funding, site and current progress. Several support projects are treated similarly. (LTN)
Progressive obstructive lung disease is a characteristic component of cystic fibrosis (CF). It is the pulmonary manifestations, including obstruction and endobronchial infection, which directly contribute...Full Text Available
Metastases to the cerebellopontine angles (CPAs) are rare. Typically, the clinical course is one of rapid onset and progression of crarial nerve deficits. The clinical presentation and course of carcinoma...Full Text Available
The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Concl...
Tick-borne encephalitis (TBE) virus causes severe encephalitis with serious sequelae in humans. The disease is characterized by fever and debilitating encephalitis that can progress to chronic illness...Full Text Available
This article outlines research and progress into the liquefaction of coal by solvent treatment, being conducted at the National Research Institute for Pollution and Resources, Japan. (In Japanese)
BackgroundCentrosome aberrations can cause genomic instability and correlate with malignant progression in common human malignancies such as breast and prostate cancer. Deregulation...Full Text Available
Frontotemporal lobar degeneration is a progressive neurodegenerative syndrome that is the second most common cause of early-onset dementia. Mutations in the progranulin gene are a major cause of familial...Full Text Available
HIV infections show great variation in the rate of progression to disease, and the role of viral genetic factors in this variation had remained poorly characterized until recently. Now a series of four...Full Text Available
... At the Vintage at Goodwood festival we're curating this summer, we intend to demonstrate how sustainability can be cool without being hippy in 2010. It really can - I'm the living embodiment of that . . .\\
In accordance with the requirements of Section 113 (b) (3) of the Nuclear Waste Policy Act of 1982, as amended (NWPA), the US Department of Energy (DOE) has prepared this report on the progress of site characterization activities at Yucca Mountain, Nevada, for the period October 1, 1990, through March 31, 1991. This report is the fourth in a series of reports that are issued at intervals of approximately six months during site characterization. The report covers a number of initiatives to improve the effectiveness of the site characterization program, and covers continued efforts related to preparatory activities, Study Plans, and performance assessment.
In the last two years, rapid progress has been made in the energy conversion efficiencies of GaAs solar cells fabricated from molecular beam epitaxy (MBE) material. The efficiencies of cells fabricated from MBE material are now comparable with those fabricated from metal-organic chemical vapor deposition material, even for cells of dimension 2 cmx4 cm. This paper reviews the progress in MBE cell efficiencies. Also discussed is the role oval defects play in GaAs diode and solar cell performance. (orig.).
The Large Hadron Collider (LHC) project, approved by the CERN Council in December 1994, has now fully entered its construction phase, with the detailed technical definition of the major systems, and the adjudication of a number of large procurement contracts. We first recall the main features and characteristics of the LHC, report on the advances in definition of the layout and optics as well as on preparation of the injector complex, and review recent progress in the key technical systems of the main ring: magnets, cryogenics and vacuum, as well as civil construction, which has started following acceptance by authorities in the Host States.
The International Linear Collider Main Linacs are based on superconducting accelerator structures operating at 1.3 GHz. The basis for this design has been developed and tested at DESY and R&D is progressing at many laboratories around the world including DESY, Orsay, KEK, FNAL, SLAC, Cornell, and JLAB. The status of the TESLA-style cavities and rf system will be reviewed and parameters for the ILC linac will be described. The role of the different linac test facilities will discussed and the critical items and R&D program to support a Conceptual Design and Technical Design will be outlined.
Progress is reported in several areas of research. The following cellulosic raw materials were selected for study: wheat, barley, and rice straws, rice hulls, sorghum, corn stover, cotton gin trash, newsprint, ground wood, and masonite steam-treated Douglas fir and redwood. Samples were collected, prepared, and analyzed for hexosans, pentosans, lignin, ash, and protein. Results of acid extraction and enzymatic hydrolysis are discussed. Yields of glucose, polyglucose, xylose, and arabinose are reported. Progress in process design and economic studies, as well as pilot plant process development and design studies, is summarized. (JGB)
This document is a progress report to the USDOE Atmospheric Radiation and Measurement Program (ARM). The overall project goal is to relate subgrid-cumulus-cloud formation, coverage, and population characteristics to statistical properties of surface-layer air, which in turn are modulated by heterogeneous land-usage within GCM-grid-box-size regions. The motivation is to improve the understanding and prediction of climate change by more accurately describing radiative and cloud processes.
This is the ninth quarterly report as required by the Hanford Federal Facility Agreement and Consent Order (Ecology et al. 1990), also known as the Tri-Party Agreement, established between the US Department of Energy (DOE), the US Environmental Protection Agency (EPA), and the Washington State Department of Ecology (Ecology). The Tri-Party Agreement sets the plan and schedule for achieving regulatory compliance and cleanup of waste sites at the Hanford Site. This report covers progress for the quarter that ended June 30, 1991. A total of 87 milestones have been completed to date. 39 refs., 1 fig.
This report--the forty-fifth of a series--is a compendium of monthly progress reports for the ORNL research and development programs that are in support of the increased utilization of coal and other fossil fuel alternatives to oil and gas as sources of clean energy. The projects reported this month include those for coal conversion process development, materials engineering, alkali metal vapor topping cycles, a coal equipment test program, an AFB coal combustor for cogeneration (CCC), engineering and support studies, process and program assistance, evironmental assessment studies, magnetic beneficiation, and AFBC demonstration plant.
Development progress of the full-flow engine fluidic control system is reported. The fluidic temperature control subsystem was transferred from IR and D status to the SNP-1 program contract 1 December 1969. Several new fluidic control concepts were explored either experimentally or analytically. Basic component and subsystem design data at simulated engine state-point conditions were secured. Component design effort during the next six months will include fabrication and simulated tests of selected ''breadboard'' configurations. (auth).
The focus of the Chernobyl Studies Project has now turned to the issue of health effects from the Chernobyl accident. Currently, we are involved in and making progress on the case-control and co-hort studies of thyroid diseases among Belarussian children. Dosimetric aspects are a fundamental part of these studies. We are working to implement similar studies in Ukraine. A major part of the effort of these projects is supporting these studies, both by providing methods and applications of dose reconstruction and by providing support and equipment for the medical teams.
Progress in the construction of Candu reactors at home and abroad is surveyed. Some A.E.C.L. research projects are also mentioned. During 1979, Candu reactors again showed their superior capacity factors, four of them being among the ten most reliable reactors in the world. Progress in construction at Pickering B, Bruce B, Point Lepreau, Gentilly-2, Darlington, Wolsung (Korea), Cordoba (Argentina), and Cernavoda (Romania) is recounted. In 1979, it was unfortunately necessary to replace installed steam generators at Pickering B, Bruce B, Point Lepreau and Gentilly-2. At Wolsung, the reactor was pre-assembled before installation, which is a new technique. (N.D.H.).
We report here the imaging findings of a rare case of a lethal form of Gorham disease in a young female patient. Multimodality imaging findings over 13 year-follow-up demonstrated progressive wide spread skeletal and soft tissue abnormalities with permeative osteolysis, pathological fractures and severe skeletal deformities. Unusual extensive osseous and soft tissue pneumatosis was illustrated on cross-sectional studies. The progressive nature of this form of Gorham disease and the subsequent complications eventually culminated in patient's death. (orig.)
We report here the imaging findings of a rare case of a lethal form of Gorham disease in a young female patient. Multimodality imaging findings over 13 year-follow-up demonstrated progressive wide spread skeletal and soft tissue abnormalities with permeative osteolysis, pathological fractures and severe skeletal deformities. Unusual extensive osseous and soft tissue pneumatosis was illustrated on cross-sectional studies. The progressive nature of this form of Gorham disease and the subsequent complications eventually culminated in patient's death. (orig.)
A lot of effort has been made to spread the application of RTOS in embedded system development in China. RTOS, #mu#C/OS and #mu#C/OS-II, with its opened source code, is well known in embedded systems. Learning RTOS, Using RTOS, becomes more and more popular. The Book of 'Micro C/OS-II The Real-Time Kennel Second Edition' was published in 2002. Here some new progress of the RTOS, especially the safety certifications, the reliability of software is introduced. (authors)
A thermal-resistant radiation sensing system using optical fiber has been developed. The system is for monitoring progress of chemical decontamination and able to measure the gamma-ray level in a hot solution of decontamination chemicals in situ. Our sensor head makes use of thermal-resistant NaI (T1) and it is connected to an optical fiber bundle. Scintillation photons pass from the NaI (T1) into the end of the bundle. This part of the system can withstand temperatures of over 100degC. At the far end of the optical fiber bundle, the scintillation photons are converted into fluorescent photons using a wavelength-shifting fiber. These photons are transferred to a distant photomultiplier tube through two thin transparent optical fibers. Furthermore, we propose a self-compensation technique for the dependence of scintillator sensitivity on. This compensation method is based on the correlation between temperature, sensitivity, and scintillation decay time. We have ...
All of the project work since the previous report has been on Phase 2B tasks. Therefore, this quarterly progress report summarizes the period's activities in Engineering, Procurement and Civil Construction. Engineering is 95% complete, but revisions and changes are still being incorporated particularly in the Instrument and Electrical areas. Procurement has only valves 4 in. and above yet to order to complete all major items purchased. The scheduled material curve was based on the original estimate of the job. The projected curve reflects the previous month's estimate. Construction of civil work is proceeding according to schedule in the field. The initial bid packages for the Mechanical General Contractor portion of the work have been reviewed and evaluated. Order placement is scheduled for the end of July. The Electrical package is due back from the bidders on July 6. It requires additional evaluation by BSC and DSO and will not be placed until ...
Ontario's Countdown Acid Rain program was formulated in 1985 and placed an annual SO{sub 2} emissions cap of 885 kilotonnes over the province from 1994. Caps were placed on emissions from the Inco nickel/copper smelter in Sudbury, the Falconbridge nickel/copper smelter in Sudbury, the Algoma iron ore sintering plant in Wawa, and Ontario Hydro fossil-fuel plants province-wide. Semi-annual reports are required of the companies, with the 6th report outlining the final planning phase and the 7th and later reports outlining implementation progress. This document summarizes the contents of the 7th set of reports and the responses of the government review team to each company's efforts. All companies have begun implementing abatement plans outlined in the final planning phase reports of December 1988 at a rapid pace and are generally on track in controlling emissions. However, all 4 company reports lack the necessary detail for a complete review of the ...
This report summarizes the progress and accomplishments in accelerator atomic physics research supported by DOE grant DE-FG02-87ER13778 from February 16, 1990 through February 15, 1993. This work involves the experimental investigation of atomic interactions in collisions of charged projectiles with neutral targets or electrons, with particular emphasis on two-electron interactions and electron-correlation effects. The processes studied are of interest both from fundamental and applied points of view. In the latter case, results are obtained which are relevant to the understanding of laboratory and astrophysical plasmas, highly-excited (Rydberg) and continuum states of atoms and ions, atomic structure effects, the interaction of ions with surfaces, and the development of heavy-ion storage-rings. The results obtained have provided the basis for several M.A. thesis projects at Western Michigan and several Ph.D. dissertation projects are currently underway. Summaries ...
'The primary objective of this research project is to acquire a deeper fundamental knowledge of acoustic cavitation and cavitation chemistry, and in doing so, to ascertain how ultrasonic irradiation can be more effectively applied to environmental problems. Four on-going projects will be described in this progress report, The first project is the destruction of carbofuran in a Near-Field Acoustical Processor (NAP), and the hydrodynamic characterization of the reactor. The second project is a comprehensive study of how ultrasonic frequency influences sonochemical reaction rates; the substrate it, the preliminary portion of this study has been hydrogen peroxide formation. The third project in progress is destruction of four polychlorinated biphenyls at 20 kHz. Work so far has been at 20 kHz, but the most significant portion of this project will involve a multi-frequency (ultrasonic frequency) study. Finally, the destruction of a ...
Beams may be viewed as directed and focussed flow of energy and information, carried by particles and electromagnetic radiation fields (ie, photons). Often, they interact with each other (eg, in high energy colliders) or with other forms of matter (eg, in fixed targets, sychrotron radiation, neutron scattering, laser chemistry/physics, medical therapy, etc.). The whole art and science of beams revolve around the fundamental quest for, and ultimate implementation of, mechanisms of production, storage, control and observation of beams -- always directed towards studies of the basic structures and processes of the natural world and various practical applications. Tremendous progress has been made in all aspects of beam physics and technology in the last decades -- nonlinear dynamics, superconducting magnets and rf cavities, beam instrumentation and control, novel concepts and collider praradigms, to name a few. We illustrate this progress with a ...
The Electrochemical Technology Program at Argonne National Laboratory (ANL) provides advanced battery R&D; technology transfer to industry; technical analyses, assessments, modeling, and databases; and independent testing and post-test analyses of advanced batteries. These capabilities and services are being offered to the US Advanced Battery Consortium (USABC) and Cooperative Research and Development Agreements (CRADA) are being negotiated for USABC-sponsored work at ANL. A small portion of DOE`s cost share for USABC projects has been provided to ANL to continue R&D and testing activities on key technologies that were previously supported directly by DOE. This report summarizes progress on these USABC projects during the period of April I through September 30, 1992. In this report, the objective, background, technical progress, and status are described for each task. The work is organized into the following task areas: 1.0 ...
During the first phase of this project, significant progress was made in several of the connected issues that make up the objectives of this grant. The central thrust or theme of this work under the DOE/ERIP grant is to carry out prototype testing of the concept of tribopolymerization as a novel mechanism of boundary lubrication--under more severe, high-load, high-speed conditions that are most likely to exist in field applications. The authors see this as an important step in attracting industries to license and market the results of this new technology. In addition, they have began to explore other potential, energy-saving applications of the concept of tribopolymerization. These exploratory studies are quite promising; they are likely to open new doors in industrial applications. To carry out the experimental part of this program, a new device has been built. Highlights of these and other developments are given.
Background:- Discrepancies exist in optometric education, practice and regulation across the Asia-Pacific region and the competence of optometric practitioners in adopting new lens technologies may vary widely. Over the past 10-years, a continuing professional development program, Varilux Academy Asia-Pacific (VAAP), was implemented and conducted in countries across the Asia-Pacific region to improve practitioners' understanding of optometric fitting principles, with special emphasis on progressive addition lenses (PAL). The aim was to demonstrate the effectiveness of VAAP and to compare the competence of practitioners across the Asia-Pacific region in new lens fitting technologies. Methods:- From 2002 to 2008, all VAAP participants from 12 countries across Asia-Pacific were invited to com...
This paper considers the technical progress in offshore pipeline construction with limitation to some general subjects covering pipeline design, installation and start-up. In future the use of limit state pipeline design philosophy, may be implemented as an alternative to the stress based design commonly used to day giving a potential for further optimisation of the pipeline design and consequently reduction of the initial investment. Comprehensive research and development efforts in Norway in the second half of the 1970`s, made it technically feasible to cross the deep water Norwegian Trench in the 1980`s. In addition, the development of several offshore pipeline systems until to day including gas distribution systems to the European continent, have brought Norway to the forefront of technical expertise
Alzheimer's disease (AD) is a progressive neurodegenerative disorder of the elderly accounting for the vast majority of dementia. Recently, many studies have implicated the role of inflammatory response, especially neuroinflammatory response in the development and progression of AD. However, the underlying mechanism of how inflammatory response induces AD is unknown. Kynurenine pathway is a major route of the amino acid tryptophan catabolism, resulting in the production of nicotine adenine dinucleotide and other neuroactive intermediates: quinolinic acid (QA) and kynurenic acid (KA). QA exerts different toxic effects, including over-activation of N-methyl-d-aspartate (NMDA) receptor and excitotoxicity, synaptic dysfunction and neuronal death. On the other hand, KA is identified as the only...
This report covers the second year of the 28 month grant current grant to Clarkson University to study the chemical and physical behavior of the polonium 218 atom immediately following its formation by the alpha decay of radon. Because small changes in size for activity result in large changes in the delivered dose per unit exposure, this behavior must be understood if the exposure to radon progeny and it dose to the cells in the respiratory tract are to be fully assessed. Two areas of radon progeny behavior are being pursued; laboratory studies under controlled conditions to better understand the fundamental physical and chemical process that affect the progeny`s atmospheric behavior and studies in actual indoor environments to develop a better assessment of the exposure of the occupants of that space to the size and concentration of the indoor radioactive aerosol. This report describes the progress toward achieving these objectives.
The H-Coal ebullated bed reactor contains at least four discrete components: gas, liquid, catalyst, and unconverted coal and ash. Because of the complexity created by these four components, it is desirable to understand the fluid dynamics of the system. The objective of this program is to establish the dependence of the ebullated bed fluid dynamics on process parameters. This will permit improved control of the ebullated bed reactor. Progress has been made in the study undertaken for defining the hydrodynamic properties of gas/liquid/solid systems as related to the H-Coal process. The literature search was completed, and a report will be issued shortly. Design and construction of the fluid dynamics unit proceeded as planned. Unit completion is scheduled for May 1, 1978.
The Surry low power and shutdown probabilistic risk analysis (PRA) is an ongoing project at Brookhaven National Laboratory (BNL) to identify and quantify potential accident scenarios that may occur in a pressurized water reactor (PWR) during low power and shutdown. It was initiated as a result of various incidents and accidents that have occurred within the United States and overseas. The project involves review and evaluation of PWR experience at shutdown, identification of accident scenarios, determination of methods to mitigate the accidents, and performance a level 1 PRA. An evaluation of accident progression, source terms and consequences has also been initiated. The results will be used to address issues related to shutdown conditions. The objective of this paper is to provide a progress report on the project, and to present the approach used as well as the preliminary results of the ongoing and completed tasks.
Progress in the worldwide capability of predicting the convective energy loss from solar central receivers is reviewed. The significant advances in the past three years have been in experimental areas. Baseline measurements of the convective heat transfer from large high-temperature surfaces, e.g., a flat plate and a cubical cavity, have been completed and empirical correlations have been obtained. Theoretical modeling activities have not kept pace with the experimental advances, however. Currently, the primary theoretical emphasis is the development and testing of turbulence models suitable for buoyant flows. Three major needs have been identified: the measurement of convective energy losses from operating solar central receivers; the continued development of theoretical models in spite of the relatively slow progress to date; and the quantification of the effects of atmospheric turbulence.
After the publication of the 2nd progress report of geological disposal of TRU waste in Japan, policy and general scheme of future study for the waste disposal in Japan was published by ANRE and JAEA. This annual report summarized aim and progress of individual problem, which was assigned into JAEA in the published policy and general scheme. The problems are as follows; characteristics of TRU waste and its geologic disposal, treatment and waste production, quality control and inspection methodology for waste, mechanical analysis of near-field, data acquisition and preparation on radionuclides migration, cementitious material transition, bentonite and rock alteration in alkaline solution, nitrate effect, performance assessment of the disposal system and decomposition of nitrate as an alternative technology. (author)
Progress in experimental investigations of high spin excitations in spherical and transitional nuclei in the A = 180 to 204 mass range is described. Most of the experiments were performed by in-beam #gamma#-ray spectroscopy using beams of "3He, "4He, and "1"2C ions from the Michigan State University cyclotron. The main results of studies of the nuclei "1"9"5 "1"9"7 "1"9"9 "2"0"1 "2"0"2 "2"0"3Pb, "1"9"6 "1"9"7 "1"9"9 "2"0"0Hg and "1"8"6 "1"8"7 "1"8"8 "1"8"9Pt are summarized.
The Muon Ionization Cooling Experiment (MICE) focusing solenoid magnets focus the muon beam within the MICE cooling channel on a liquid or solid absorber that is within the warm bore of solenoid. The focusing magnet has a warm bore of 470 mm. his magnet consists of two coils 210-mm long that is separated by an aluminum mandrel that is 200 mm long. Each of the coils has its own leads. The coils may be operated in either the non-flip mode (solenoid mode with both coils at the same polarity) or the lip mode (quadrupole focusing mode where both coils are at opposite polarity). This report describes the focusing solenoid magnet design that will be built by the vendor. The progress on the construction of the first of the focusing magnets will also be discussed in this report. Ultimately three of these magnets will be built. These magnets will be cooled using a pair 1.5 W (at 4.2 K) pulse tube coolers.
A previous note reviewed methods for the paramagnetic doping of materials for spin-polarized solid targets and some of the history of attempts to apply those methods to hydrocarbons. Since the earlier work on hydrocarbons had yielded, at best, rather mediocre results, that note also speculated on some ways to extend and, possibly, to improve upon the earlier work. The sharpest focus was on the light (number of carbons less than six) alkanes, since these are the hydrocarbons that have the highest hydrogen contents ([approx gt] 17wt %) and therefore require the least degree of polarization to be interesting. This present note summarizes the subsequent work done, to date, exploring some of the issues related to the chemical doping method. The main areas of progress have been in the literature search, experimental results on glass formation by alkanes, and a polarizing test of a prototype'' hydrocarbon.
A previous note reviewed methods for the paramagnetic doping of materials for spin-polarized solid targets and some of the history of attempts to apply those methods to hydrocarbons. Since the earlier work on hydrocarbons had yielded, at best, rather mediocre results, that note also speculated on some ways to extend and, possibly, to improve upon the earlier work. The sharpest focus was on the light (number of carbons less than six) alkanes, since these are the hydrocarbons that have the highest hydrogen contents ([approx gt] 17wt %) and therefore require the least degree of polarization to be interesting. This present note summarizes the subsequent work done, to date, exploring some of the issues related to the chemical doping method. The main areas of progress have been in the literature search, experimental results on glass formation by alkanes, and a polarizing test of a prototype'' hydrocarbon.
A previous note reviewed methods for the paramagnetic doping of materials for spin-polarized solid targets and some of the history of attempts to apply those methods to hydrocarbons. Since the earlier work on hydrocarbons had yielded, at best, rather mediocre results, that note also speculated on some ways to extend and, possibly, to improve upon the earlier work. The sharpest focus was on the light (number of carbons less than six) alkanes, since these are the hydrocarbons that have the highest hydrogen contents ({approx_gt} 17wt %) and therefore require the least degree of polarization to be interesting. This present note summarizes the subsequent work done, to date, exploring some of the issues related to the chemical doping method. The main areas of progress have been in the literature search, experimental results on glass formation by alkanes, and a polarizing test of a ``prototype`` hydrocarbon.
The operation of the negative ion based NBI system for JT-60U has been progressed since 1996. Most of the efforts in the operation for increasing beam power and energy have been concentrated to get over the troubles, caused by surge energy at the moment of the accelerator break-down, in the ion sources and high voltage power supplies. The ion source for the N-NBI, so far, has accelerated negative ion beams of 14.3 A at 380 keV with deuterium and 18.5 A at 360 keV with hydrogen against the target of 22 A. The neutral beam power injected into JT-60U has already reached 5.2 MW at 350 keV for 0.7 sec with deuterium. (author)
Remotely sensed ocean color data and numerical modeling have been used to study the phenology of both spring and fall phytoplankton blooms (FPBs) in the Nova Scotian Shelf (NSS)-Gulf of Maine (GoM) region. The ocean color data reveal a general pattern of westward progression of the spring phytoplankton bloom (SPB), and an eastward progression of the FPB in the NSS-GoM region. The spatial pattern of mean chlorophyll concentration in spring is similar to that in fall, with a lower concentration in the NSS and higher in the GoM. Interannually, there is a weak but significant tendency for years with earlier (delayed) SPBs to be followed by delayed (earlier) FPBs, but the mean chlorophyll concentrations during SPBs are not correlated with those during FPBs. The interannual variability of SPB ti...
The purpose of this project is to demonstrate targeted infill and extension drilling opportunities, better determinations of oil-in- place, methods for improved completion efficiency and the suitability of waterflooding in certain shallow-shelf carbonate reservoirs in the Williston Basin, Montana, North Dakota and South Dakota. Improved reservoir characterization utilizing 3-dimensional (3D) and multi-component seismic are being investigated for identification of structural and stratigraphic reservoir compartments. Field demonstrations are in progress to collect data for evaluation of horizontal completions in both the Red River and Ratcliffe. A vertical well in the Red River will test attribute analysis of 3D seismic data for prediction of porosity development. Additional seismic acquisitions and interpretation are in progress for both the Ratcliffe and Red River. A water-injectivity test in a new horizontal completion in the Red Rive B zone ...
The gastrointestinal transit was studied in 20 patients with loop transverse colostomies and previously normal colons. This analysis was performed through radiological observation of progression of 20 radiopaque pellets and measurements of its transit time in the various segments of the digestive tract. An evaluation of other related clinical and radiological events was carried out sentimentality's. In order to better understand the influence of the surgical procedure, the study was performed under similar dietary and supportive care conditions and standard radiological studies before and after the re-establishment of transit, thus enabling a comparison with the same individual. (author)
Successful electron capture dissociation (ECD) Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) applications to peptide and protein structural analysis have been enabled by constant progress in implementation of improved electron injection techniques. The rate of ECD product ion formation has been increased to match the liquid chromatography and capillary electrophoresis timescales, and ECD has been combined with infrared multiphoton dissociation in a single experimental configuration to provide simultaneous irradiation, fast switching between the two techniques, and good spatial overlap between ion, photon, and electron beams. Here we begin by describing advantages and disadvantages of the various existing electron injection techniques for ECD in FT-ICR MS. We next ...
Research and bioethical policies are increasingly seen to facilitate, rather than to impede, scientific progress. Bioethical structures, nonetheless, often fail to account for or to shape the specific social surrounds in which scientific research is conducted. In Taiwan, a perceived shortage in human biological donations threatens to hamper stem cell research progress. This paper considers the stalled national biobank project and the lack of a reliable embryo supply for stem cell research, and suggests that one must look beyond regulatory structures in seeking explanations for such shortages. Specific aspects of Taiwan's democratization and social changes combine with problematic relations between patients and physicians to shape the terrain upon which human biologicals are given or withhe...
Special education researchers have made noteworthy progress toward conceptualizing literacy research questions, designing quality studies, and disseminating the results of their research. These advancements have been made through the establishment and refinement of quality research indicators. Unfortunately, this progress has mostly eluded the arena of juvenile justice special education research. The purpose of this article is to review juvenile justice literacy studies and provide juvenile justice personnel and researchers with methodological and practical considerations for improving the quality of juvenile justice literacy research. The focus is on advancing group designs. Practical concerns are based on the first-year experiences of researchers who implemented an Institute of Education Sciences Goal 3 study with the aim of determining the efficacy of literacy instructional programs in a juvenile justice setting.
The ARE progress report discusses the following issues: Economic development and its effects on power supply; Deregulation of the electricity and gas market; Competition between regional utilities; Energy policy of the new German government; European regulations; Legislation on energy supply; Energy supply and cartel law; Regional supply in the East German states. [German] Der Taetigkeitsbericht der ARE befasst sich mit folgenden Themen: Gesamtwirtschaftliche Entwicklung und ihre Auswirkung auf die Energiewirtschaft, Oeffnung des Monopoles fuer Strom und Gas, Wettbewerb der regionalen Energieversorger, Energiepolitik der neuen Bundesregierung, Europaeische Richtlininen, energiewirtschaftsrecht, Versorgungswirtschaft und Kartellrecht und der Regionalversorgung in den neuen Bundeslaendern.
Corrosion is said to be the most dominant factor which affects the physical life of ships and offshore structures. In order to secure the structural safety of ships and offshore structures, it is necessary to take measures to corrosion based on the prediction of condition of progressive corrosion. But such prediction is difficult because the behavior of corrosion`s progress is probabilistic. In this paper, probabilistic model, which could evaluate the degradation of coatings and the successive corrosion of steel members, was proposed in order to explain the tendency of the actual corrosion conditions of existing ships. Then, statistical inferences on the proposed model were made by applying the actual data on plate thickness measurements of Bulk Carriers` Cargo Hold. And validity of the proposed model was verified.
BackgroundAlthough benign ampullary tumors are removed endoscopically, due to their potential to progress to malignant disease, the favored treatment for adenocarcinoma is pancreaticoduodenectomy. We reviewed our institutions experience in order to identify which patients were at highest risk of disease progression following surgical resection, as well as evaluate whether localized T1 tumors are best treated by pancreaticoduodenectomy. MethodsWe retrospectively reviewed 157 patients who presented with an ampullary mass, from 2001 to 2010, and identified 51 with benign adenoma and 106 with adenocarcinoma. ResultsPatients with malignant tumors most often presented with larger tumors and jaundice, which alone was predictive of survival (OR = 67). Forty-five percent of patients with pathologic...
Summary Background Sorafenib is an oral multikinase inhibitor that blocks cell proliferation via the ERK pathway and angiogenesis via the VEGF pathway. This phase II trial was conducted to determine the efficacy and tolerability of sorafenib for the treatment of patients with metastatic urothelial cancer (UC) who had not had prior chemotherapy for advanced disease. Patients and Methods Seventeen chemo-na?ve UC patients with adequate performance status and organ function were treated with sorafenib 400?mg twice daily on a continuous basis until progression or unacceptable toxicity. The primary endpoint was objective tumor response rate as measured by RECIST criteria. Secondary endpoints included rate of prolonged stable disease (>3?months), time to progression, median and 1?yr survival and ...
Full text: Founded in 1964, Ankara Nuclear Research and Training Center (ANRTC) conducts and facilitates the scientific activities including training (summer practice, MSc and Ph D studies in physics and chemistry, IAEA fellowship programs etc.), research and other studies in nuclear and related fields. As it's a part of main duties, ANRTC has analysis on the variety of samples, and radiation protection services commercially, for radiation workers in state, public and private sectors. Research, development and application projects implemented in this Center have mostly been supported by State Planning Organization (SPO) and Turkish Atomic Energy Authority (TAEA). In addition to the projects there are on going collaborative studies with some national Universities and International Atomic Energy Agency. The main activities carried out in ANRTC can be summarized as: studies on experimental nuclear physics, application of nuclear techniques such as XRF, XRD, Gamma, Alpha, etc. for ...
A study was undertaken to examine the uptake, distribution, and interaction of five activation products (Co-57, Be-7, Cs-134, Rb-83, and Mn-54) within the biotic and abiotic components surrounding the waste treatment lagoons of the Los Alamos Meson Physics Facility (LAMPF). The study attempted to ascertain where, and what specific interactions were taking place among the isotopes and the biotic/abiotic components. A statistical approach, utilizing Multivariate Analysis of Variance (MANOVA), was conducted testing the radioisotopic concentrations by (1) the trophic levels (TROPLVL) in each position sampled on the grid, (2) where sampled on the grid (TRAN), (3) where sampled with-in each grid line (PLOT), and (4) the side with which sampled (SIDE). This provided both the dependent and independent variables that would be tested. The Null Hypothesis (Ho) tested the difference in the mean values of the isotopes within/between each of the four independent variables. The ...
A study was undertaken to examine the uptake, distribution, and interaction of five activation products (Co-57, Be-7, Cs-134, Rb-83, and Mn-54) within the biotic and abiotic components surrounding the waste treatment lagoons of the Los Alamos Meson Physics Facility (LAMPF). The study attempted to ascertain where, and what specific interactions were taking place among the isotopes and the biotic/abiotic components. A statistical approach, utilizing Multivariate Analysis of Variance (MANOVA), was conducted testing the radioisotopic concentrations by (1) the trophic levels (TROPLVL) in each position sampled on the grid, (2) where sampled on the grid (TRAN), (3) where sampled with-in each grid line (PLOT), and (4) the side with which sampled (SIDE). This provided both the dependent and independent variables that would be tested. The Null Hypothesis (Ho) tested the difference in the mean values of the isotopes within/between each of the four independent variables. The ...
Radioisotopes of Pb(II) have been of some interest in radioimmunotherapy and radioimmunoimaging (RII). However, the absence of a kinetically stable bifunctional chelating agent for Pb(II) has hampered its use for these applications. {sup 203}Pb (T{sub 1/2}=52.02 h) has application potential in RII, with a {gamma}-emission that is ideal for single photon emission computerized tomography, whereas {sup 212}Pb (T{sub 1/2}=10 h) is a source of highly cytotoxic {alpha}-particles via its decay to its {sup 212}Bi (T{sub 1/2}=60 min) daughter. The synthesis of the novel bifunctional chelating agent 2-(4-isothiocyanotobenzyl)-1,4,7,10-tetraaza-1,4,7,10-tetra-(2-carbamoyl methyl)-cyclododecane (4-NCS-Bz-TCMC) is reported herein. The Pb[TCMC]{sup 2+} complex was less labile to metal ion release than Pb[DOTA]{sup 2-} at pH 3.5 and below in isotopic exchange experiments. In addition to increased stability to Pb{sup 2+} ion release at low pH, the bifunctional TCMC ligand was ...
Radioisotopes of Pb(II) have been of some interest in radioimmunotherapy and radioimmunoimaging (RII). However, the absence of a kinetically stable bifunctional chelating agent for Pb(II) has hampered its use for these applications. "2"0"3Pb (T_1_/_2=52.02 h) has application potential in RII, with a #gamma#-emission that is ideal for single photon emission computerized tomography, whereas "2"1"2Pb (T_1_/_2=10 h) is a source of highly cytotoxic #alpha#-particles via its decay to its "2"1"2Bi (T_1_/_2=60 min) daughter. The synthesis of the novel bifunctional chelating agent 2-(4-isothiocyanotobenzyl)-1,4,7,10-tetraaza-1,4,7,10-tetra-(2-carbamoyl methyl)-cyclododecane (4-NCS-Bz-TCMC) is reported herein. The Pb[TCMC]"2"+ complex was less labile to metal ion release than Pb[DOTA]"2"- at pH 3.5 and below in isotopic exchange experiments. In addition to increased stability to Pb"2"+ ion release at low pH, the bifunctional TCMC ligand was found to have many other ...
The potential application of radioisotopes are not discussed in this review of trypanosome pathogenesis in cattle. Initially, structural changes in the lymphoid system are characterized by marked proliferation and germinal centre formation, whereas in long-standing infections the lymphoid organs become depleted. These changes appear associated with immunodepression. Anaemia dominates the clinical disease syndrome in bovine trypanosomiasis. It develops with the onset of parasitaemia and is largely haemolytic, resulting from increased red blood cell destruction by phagocytosis. Several factors may be involved in this process including haemolysins produced by the trypanosome, immunological mechanisms, fever, disseminated intravascular coagulation and an expanded and active mononuclear phagocytic system. During this phase of the disease, cattle respond well to chemotherapy. However, in later phases of the disease, when trypanosomes cannot be detected, the anaemia ...
In radiation processing of food, the product often has to be prepackaged to prevent microbial recontamination during and after irradiation. The packaging material is exposed to radiation during radiation processing and radiation stability is a key consideration in the selection of packaging materials. The effects of ionizing radiation on many food packaging materials at the dose levels recommended for food precessing can be minimized by selecting appropriate radiation resistant materials. It is important to select materials in which chemicals formed as a result of the radiation treatment do not migrate and interact with the food, affecting its organoleptic and toxicological aspects. It is also important to select materials in which the physical properties are not altered to the extent they cannot resist damage during commercial production, shipment and storage. Radiation treatment of food may be classified broadly into two categories: 1. Processes requiring doses less than 10 kGy; 2. ...
The measurements of the L X-ray intensity ratio I(L{alpha})/I(L{beta}), I(L{alpha})/I(L{gamma}), I(L{alpha})/I(L{iota}), I(L{beta})/I(L{gamma}) and I(L{iota})/I(L{gamma}) for elements Dy, Ho, Yb, W, Hg, Tl and Pb were experimentally determined both by photon excitation, in which 59.5 keV {gamma}-rays from a filtered radioisotope {sup 241}Am was used, and by the radioactive decay of {sup 160}Tb, {sup 160}Er, {sup 173}Lu, {sup 182}Re, {sup 201}Tl, {sup 203}Pb and {sup 207}Bi. L X-rays emitted by samples were counted by a Si(Li) detector with resolution 160 eV at 5.9 keV. Obtained values were compared with the calculated theoretical values. Theoretical values of the I(L{alpha}/L{beta}), I(L{alpha}/L{gamma}), I(L{alpha}/L{iota}), I(L{beta}/L{gamma}) and I(L{iota}/L{gamma}) intensity ratios were calculated using theoretically tabulated values of subshell photoionization cross-section, fluorescence yield, fractional X-ray emission rates, Coster-Kronig transition ...
The effect that different chemical and physical atomic environments can have on the relative intensities of radiative electron transitions from the filling of K shell vacancies was investigated. The method used involved the detection of photoionization induced X-ray fluorescence. An experimental system based on a hyper pure germanium detector (HPGE) was used to measure the relative K-L and K-M X-ray yields from the photofluorescence of a series of lanthanide elements and compounds. A background subtraction and peak integration strategy was employed which accounted for scattering in the samples and scattering of the flux from the radioisotope photoionization sources. Analysis of the data resulted in a tabulation of relative K/sub ..beta..//K/sub ..cap alpha../ X-ray intensity ratios. The measured relative K/sub ..beta..//K/sub ..cap alpha../ X-ray intensity ratios were compared to the calculated values predicted by the theoretical development of Scofield and the ...
The effect that different chemical and physical atomic environments can have on the relative intensities of radiative electron transitions from the filling of K shell vacancies was investigated. The method used involved the detection of photoionization induced X-ray fluorescence. An experimental system based on a hyper pure germanium detector (HPGE) was used to measure the relative K-L and K-M X-ray yields from the photofluorescence of a series of lanthanide elements and compounds. A background subtraction and peak integration strategy was employed which accounted for scattering in the samples and scattering of the flux from the radioisotope photoionization sources. Analysis of the data resulted in a tabulation of relative K/sub #beta#//K/sub #alpha#/ X-ray intensity ratios. The measured relative K/sub #beta#//K/sub #alpha#/ X-ray intensity ratios were compared to the calculated values predicted by the theoretical development of Scofield and the average of previous ...
This is the 1st revision of the INIS/ETDE Joint Thesaurus. It contains 20 953 valid descriptors and 8 600 forbidden terms. It was last updated in December 2003. The Joint Thesaurus contains the controlled terminology for indexing all information within the subject scope of both INIS (International Nuclear Information System) and ETDE (Energy Technology Data Exchange) information systems. The terminology is intended for use in subject description for input or retrieval of information in those systems. The thesaurus is a terminological control device used in translating from the natural language of documents, indexers or users into a more constrained system language It is also a controlled and dynamic vocabulary of semantically and generically related terms which covers a specific domain of knowledge. The domain of knowledge covered by this Thesaurus includes physics (in particular, plasma physics, atomic and molecular physics, and especially nuclear and high-energy physics), chemistry, ...
General-Purpose Heat Source radioisotope thermoelectric generators (GPHS-RTGs) will provide electrical power for the NASA Galileo and European Space Agency (ESA) Ulysses missions. Each GPHS-RTG comprises two major components: GPHS modules, which provide thermal energy, and a thermoelectric converter, which converts the thermal energy into electrical power. Each of the 18 GPHS modules in a GPHS-RTG contains four /sup 238/PuO/sub 2/-fueled capsules. LANL conducted a series of safety verification tests on the GPHS-RTG before the scheduled May 1986 launch of the Galileo spacecraft to assess the ability of the GPHS modules to contain plutonia in potential accident environments. As a result of the Challenger 51-L accident in January 1986, NASA postponed the launch of Galileo; the spacecraft launch vehicle was reconfigured and the spacecraft trajectory modified. These actions prompted NASA to reevaluate potential mission accidents and the extended series safety test ...
The excitation function of the {sup 64}Ni({alpha},p){sup 67}Cu reaction was measured from threshold up to 24 MeV in order to investigate the possibility of production of the {beta}{sup -}-emitting therapeutic radioisotope {sup 67}Cu (T{sub 1/2}=61.9 h). Two stacks of thin metallic self-supporting foils of {sup 64}Ni (enrichment 77.8%) prepared by electrolytic deposition were irradiated by {alpha}-particle beams. The radioactivity was determined via HPGe detector {gamma}-ray spectrometry. Some {sup 67}Ga activity (which emits the same {gamma}-rays as {sup 67}Cu), formed via the {sup nat}Cu({alpha},x){sup 67}Ga process on trace copper impurity in the Ni foils, was also observed. Corrections were done for {sup 67}Ga activity contribution and for the {sup 67}Cu activity escape fraction from the thin Ni-foil. The maximum cross section of the {sup 64}Ni({alpha},p){sup 67}Cu reaction amounts to 34 mb at 22 MeV. The experimental results were compared with theoretical ...
Full text: Certain groups of patients have been excluded from ventilation lung scanning due to their inability to comply with instruction. Tetley Manufacturing have recently developed a Positive Ventilation Delivery System (PVDS) which assists in delivering Technegas to patients who are unable to cooperate fully. The aim of this study is to evaluate the PVDS in the clinical setting. Fifteen frail aged and psychogeriatric patients (n=l 5), mean age 78 years (range 60-93), were ventilated with Technegas using the PVDS. The decision to ventilate the patient with the PVDS was based on an initial assessment of the patients ability to comply with instructions, or failure of the conventional ventilation method, to produce an adequate count rate. Technegas was prepared in the usual manner and then delivered to the patients lungs by squeezing a black anesthetic bag synchronously with the patients breathing, until a count rate of approximately 1000 counts/second was obtained. All patients ...
Nowadays there is a growing interest in the study of natural radioactivity levels, mainly of radionuclides; {sup 238}U, {sup 226}Ra, {sup 232}Th, {sup 40}K, and {sup 210}Pb present in the environment. The environmental radioactivity control is very important to obtain information on exposure of humans and vegetables to potential sources on natural radioactive occurrences. Industrial processes involving mining and extraction and production of oil foster concentration of radionuclides, contributing to the occurrence of what is known as 'TENORM' - Technologically Enhanced Naturally Occurring Radioactive Material. This work aims to assess the environmental radiological impact on the estuarine area of the Industrial Park of SUAPE, due the installation of an oil refinery and the consequent introduction on the environment of natural radioactive materials from other regions in that area. The radioisotopes {sup 238}U, {sup 226}Ra, {sup 232}Th , {sup 40}K ...
The distribution of carrier-free "2"0"3Pb-acetate, "2"0"3HgCl_2, "5"7Cocl_2, "1"3"7CsCl and "2"0"1TlCl was investigated in rats bearing thigh-implanted Morris 7777 hepatomas. Viable and nonviable tumor tissue was collected in order to determine the relative affinities of the radiopharmaceutical for these tissues. The animals were sacrificed at 4, 24, 48, 72 and 96 hrs following intravenous injection. Washout of the radioisotope from the viable tumor tissue was rapid, the maximum concentration being reached on or before 4 hrs following injection. In contrast, residual activity within the nonviable tumor tissue decreased much more slowly and in some cases even increased with time. Viable tumor-to-muscle and nonvialbe tumor-to-muscle ratios for "2"0"3Pb, "2"0"3Hg and "5"7Co were comparable to the analogous ratios reported for "6"7Ga. However, none of these isotopes approached "6"7Ga as a potential tumor imaging agent because the large ratios were the result of low ...
Colorectal carcinoma is a highly prevalent and common cause of cancer in Taiwan. There is still no available cure for this malignant disease. To address this issue, we applied the multimodality of molecular imaging to explore the efficacy of diagnostic and therapeutic nanoradiopharmaceuticals in an animal model of human colorectal adenocarcinoma [colorectal cancer (CRC)] that stably expresses luciferase (luc) as a reporter. In this study, an in vivo therapeutic efficacy evaluation of dual-nanoliposome (100 nm in diameter) encaged vinorelbine (VNB) and "1"1"1In-oxine on HT-29/luc mouse xenografts was carried out. HT-29/luc tumor cells were transplanted subcutaneously into male SCID mice. Multimodality of molecular imaging approaches including bioluminescence imaging (BLI), gamma scintigraphy, whole-body autoradiography (WBAR) and in vivo tumor growth tracing, histopathology and biochemistry/hematology analyses were applied on xenografted SCID mice to study the treatments with 6% ...
Different types of generators have been developed for the convenient use of {sup 99m}Tc as the demand for this radioisotope is strong. Currently, the demand for {sup 99m}Tc is more than 80 % of the total demand for medical isotopes in the world. A {sup 99m}Tc generator, in general, is composed of a column packed with ceramic adsorbent, tubing, eluent reservoir or vials, collection vials, and shielding. The key technology to develop a good generator is how to load {sup 99}Mo as much as possible while maintaining the quality of eluted {sup 99}mTc as good as possible. The technology is well developed and already available commercially for the case of the fission {sup 99}Mo/{sup 99}mTc because loading of few curries of {sup 99}Mo on a conventional adsorbent, i.e. alumina is not a serious task in the chemical point of view. However, the current infrastructure of the supply of {sup 99}Mo to the world market is sturdy as the research reactors are getting aged. In this ...
The major effect of immobilization during growth is a smaller bone mass induced by either an increased bone resorption or a decreased bone formation. Using a method of analyzing radioisotopic loss of (/sup 3/H)tetracycline and (/sup 3/H)collagen from bone prelabeled in vivo, we compared the amount of bone resorption due to immobilization with bone resorption induced by growth. One hind limb was denervated in growing male rats, 6 weeks of age, that had been chronically prelabeled with (/sup 3/H)tetracycline, /sup 45/calcium, and (/sup 3/H)proline. The total radioactivity of the whole femur and tibia/fibula from the denervated limb was compared with that from bones of the control limb at 0, 1, 2, 4, and 8 weeks after denervation. The effect of growth on bone formation was measured by net increases in bone length, volume, and mass of matrix and mineral. Experimental bones had a significantly smaller volume and mass. Bone resorption was much greater during growth ...
Lipiodol, lipid soluble contrast media, was applied to 59 patients, who was clinically suspected to have hepatic tumor, in the Department of Diagnostic Radiology, Seoul National University Hospital. The results of the clinical use of Lipiodol were as follows: 1. The clinical diagnosis was hepatocellular carcinoma (HCC) in 50 cases, cavernous hemangioma in 4 cases, metastasis in one case and others in 4 cases. 2. After hepatic arteriography, Lipiodol only was injected in 28 cases, mixture of Lipiodol and Mitomycin was injected in 22 cases and transcatheter arterial embolization was performed additionally after injection of Lipiodol and Mitomycin in 9 cases. 3. Among the 50 cases of HCC, Lipiodol was accumulated in the lesion in 49 cases. However, similar accumulation of Lipiodol occured in a metastatic cancer and cavernous hemangiomas. 4. Plain radiographic patterns of Lipiodol accumulation could be divided into fine granular type, nodular type and linear or branching type. The linear ...
As an important radioisotope in nuclear industry and other fields, americium-241 is one of the most serious contamination concerns duo to its high toxicity and long half-life. In this experiment, the biosorption of {sup 241}Am from solution by Candida sp., and the effects of various experimental conditions on the adsorption were investigated. The preliminary results showed that the adsorption of {sup 241}Am by Candida sp. was efficient. {sup 241}Am could be removed by Candida sp. of 0.82 g/L (dry weight) from {sup 241}Am solutions of 5.6-111 MBq/L (44.3-877.2 {mu}g/L)(C{sub 0}), with maximum adsorption rate (R) of 98% and maximum adsorption capacities (W) of 63.5 MBq/g biomass (dry weight) (501.8 {mu}g/g). The biosorption equilibrium was achieved within 4 hour and the optimum pH was pH = 2. No significant differences on {sup 241}Am adsorption were observed at 10 C-45 C, or in solutions containing Au{sup 3+} or Ag{sup +}, even 1500 times or 4500 times above the {sup ...
As an important radioisotope in nuclear industry and other fields, americium-241 is one of the most serious contamination concerns duo to its high radiation toxicity and long half-life. In this experiment, the biosorption of "2"4"1Am from solution by a fungus, Saccharomyces cerevisiae (S. cerevisiae), and the effects of various experimental conditions on the biosorption and the mechanism were explored. The preliminary results showed that S. cerevisiae is a very efficient biosorbent. An average of more than 99% of the total "2"4"1Am could be removed by S. cerevisiae of 2.1g/L (dry weight) from "2"4"1Am solutions of 2.22MBq/L -555 MBq/L (Co). The adsorption equilibrium was achieved within 1 hour and the optimum pH ranged 1-3. The culture times of more than 16 hours were suitable and the efficient adsorption of 241Am by the S. cerevisiae could be noted. The biosorption of 241Am by the decomposed cell wall, protoplasm or cell membrane of S. cerevisiae was same ...
Metal waste generated from domestic nuclear operation for defense and commercial application has led to a growing stockpile of radioactively contaminated scrap metal, much of which is stainless steel. A significant fraction of this material cannot be efficiently surface decontaminated. The burial of this material would be wasteful and expensive, since long term monitoring would be necessary in order to minimize environmental risk. Much of this waste consists of bulky equipment. In many case, this equipment contains valuable material that may be recycled. The piece of equipment considered frequently also has complex geometries, making extremely difficult, time-consuming and expensive to determine the exact location and level of radioactivity on the internal surfaces. After melting, however, the radioactivity may be precisely determined from samples of each ingot. Moreover, an ingot may be released for restricted or unrestricted reuse, or stored for decay to appropriated limits. Melting ...
Experimental excitation functions for deuteron-induced reactions up to 20 MeV on high purity natural hafnium were measured with the activation method using a stacked foil irradiation technique. Metallic hafnium foils with thickness of 10 #mu#m were stacked together with 50 #mu#m thick aluminium and 12 #mu#m thick titanium foils. The aluminium foils served as energy absorber while the titanium foils were used to monitor the energy and intensity of the bombarding deuteron beam. From a detailed remeasurement of the complete excitation function of the "n"a"tTi(d,x)"4"8V monitor reaction it was possible to adopt the proper incident energy and beam intensity by comparing the results with the recommended values. High resolution off-line gamma-ray spectrometry was applied to assess the activity of each foil. From the measured activity independent and/or cumulative elemental or isotopic cross section data for production of Ta, Hf and Lu radioisotopes by (d,x) reactions were ...
A gel-type "9"9Mo-"9"9"mTc generator using Titanium-Molybdate target (TiMo-target) as column packing was developed in Radioisotope Department, the Dalat Nuclear Research Institute [1]. The concentration of trace elements in TiMo-target and radionuclidic purity in "9"9"mTc solution eluted from this type of generator were studied for quality control purpose. The monostandard method in neutron activation analysis has been applied to determine the concentration of trace impurities in titanium-molybdate target. For neutron activation analysis, TiMo samples were irradiated in the different channels of nuclear reactor IVV-9 at a neutron flux of maximum 2.1 x 10"1"3 n.cm"-"2s"-"1. The following chemical element impurities were determined: Na, W, Co, Fe, Zn, Ag, Sb and Cr. The gamma ray emitted nuclides found in "9"9"mTc solution eluted from our "9"9"mTc generator were the following: "6"5Zn, "6"0Co, "1"1"0"mAg, "5"9Fe, "5"1Cr, "2"4Na, "8"2Br and "9"9Mo. "9"9Mo was found ...
The work of this association is cut according to 6 axes. Three publications: radiological quality of marine and continental waters of the Normandy coast (synthesis 1997 and 1998); preliminary study of the iodine 129 distribution in the environment of the reprocessing plant of La Hague with terrestrial moss (Homalotecium sericeum); radiological surveillance of the aquatic environment of the nuclear facilities on the area of La Hague (1997 and 1998). The second axis concerns the radiation protection with a campaign of radon measures in a school of the Vire rural district (june 1999). The third part is devoted to the radioecology with the surveillance of radioactivity in the aquatic continental environment of nuclear facilities and the radioecological surveillance (1999) of the building site of Cogema la Hague in the area of tidal range of the Moulinets cove. The fourth part concerns the radioactive waste and environment, with the study of the distribution of the artificial gamma emitters ...
This paper addresses the background and the continuously evolving topics of hardening and electronic components. Typical radiation environments from 1960 are described. Examples of a civilian satellite and of future particle physics colliders help illustrate hardening problems. Effects in components, limits of shielding, and three methods of providing components are described. The authors conclude by focusing on both future trends of radiation environments and anticipated progress in electronics. (authors). 10 refs., 9 figs., 4 tabs.
The Myc oncoprotein is a potent inducer of cell growth, cell cycle progression, and apoptosis. While many direct Myc target genes have been identified, the molecular determinants of Myc’s transcriptional...Full Text Available
BackgroundAdipokines, e.g. TNFα, IL-6 and leptin increase insulin resistance, and consequent hyperinsulinaemia influences breast cancer progression. Beside its mitogenic...Full Text Available
Research commenced in FY 97 to determine the suitability of superplasticized cement-sand grouts for backfilling vertical boreholes used with geothermal heat pump (GHP) systems. The overall objectives were to develop, evaluate and demonstrate cementitious grouts that could reduce the required bore length and improve the performance of GHPs. This report summarizes the accomplishments in FY 98.
This report is directed at the commercial potential of the 17-m, 100 kW Darrieus Vertical Axis Wind Turbine (VAWT) developed under DOE funding by Sandia National laboratories (SNL) and Alcoa Laboratories. Three of the turbines have come on line over the past 14 months and long-term testing is in progress. As the first commercially adapted Darrieus turbines built by DOE, the superior cost, structural integrity, and output characteristics demonstrated by the prototypes appear particularly promising.
This autumn, Nice welcomed the thirteen European photovoltaic conference. It was the occasion for the world of solar energy to measure technical progress which were carried out and the market which are still to win. If developing countries are a reserve of new markets, they are not solvent and programmes depend on North/South negotiations. (N.C.).
Background/AimsFabry disease is an X-linked recessive and progressive disease caused by α-galactosidase A (α-GaL A) deficiency. We sought to assess the prevalence...Full Text Available
DescriptionAbstract of Research Proposal The root environment has a major effect on crop growth, both directly through the supply of water and nutrients to the shoot, and indirectly through root to shoot signalling. Better management of crop root systems through agronomic and genetic means has the potential to improve the efficiency of water and nutrient uptake, and limit root restrictions to crop growth. However, progress in this area is currently limited by the lack of sensors for in situ estimates of [continued...
The deregulated kinase activity of p210-BCR/ABL oncoproteins, hallmark of chronic myelogenous leukaemia (CML), induces and sustains the leukaemic phenotype, and contributes to disease progression....Full Text Available
Research and development activities are reported on absorption spectroscopy, calorimetry, electrolysis, emission spectroscopy, fluorimetry gas chromatography, infrared spectroscopy, liquid chromatography, liquid scintillation counting, mass spectroscopy, microscopy, radiometric analysis, and thermal analysis. A group of miscellaneous projects are also described.
This article discusses the latest developments made in the field of technology used for coal liquefaction. Some new areas of development in research and development work are described. Particular consideration is given to low-severity processing. This has two advantages, mostly low-molecular-weight fragments are produced and the extracts are low in heteroatoms. A detailed description of low-severity processing is given. The refining of the liquids produced from coal is also covered.
After reviewing some of the mathematical foundations and numerical difficulties facing lattice QCD, I review the status of several calculations relevant to experimental high-energy physics. The topics considered are moments of structure functions, which may prove relevant to search for new phenomena at the LHC, and several aspects of flavor physics, which are relevant to understanding CP and flavor violation.
Phthalate esters (PE's) are plasticizers used to soften PVC-based medical devices. PE's are the most abundant man-made pollutants and increase the risk of developing an allergic respiratory disease...Full Text Available
After slow progress in the efforts to develop phase plates for electron microscopes, functional phase plate using thin carbon film has been reported recently. It permits collecting high-contrast images...Full Text Available
The initiation and progression of several forms of retinal degenerations involve excessive, repetitive, and/or sustained oxidative stress that, in turn, mediate photoreceptor cell damage and...Full Text Available
Separate abstracts were prepared for 20 papers in this conference report and includes all papers in the ''engineering'' section (program E). Ocean thermal energy conversion (OTEC), moorings, cables, corrosion protection, corrosion testing, coatings, offshore platforms, pipelines, OTEC models and pilot plants, and energy transfer are topics discussed.
The uncertainties of growth in Croatian future energy, particularly electricity demand, together with growing environmental considerations and protection constraints, are such that Croatia needs to have flexibility to respond by having the option of expanding the nuclear sector. The paper deals with nuclear energy as an option for croatian sustainable economic development. The conclusion is that there is a necessity for extended use of nuclear energy in Croatia because most certainly nuclear energy can provide energy necessary to sustain progress. (author).
Research is being carried out in this project in two areas which are of interest to ongoing investigations at the Pittsburgh Energy Technology Center (PETC). They are: (a) thermal behavior of slurry reactors used for indirect coal liquefaction; and (b) coal liquefaction under supercritical conditions. The current status of each of these tasks is summarized in this report. 76 refs., 23 figs., 6 tabs.
Research is being carried out in this project in two areas which are of interest to ongoing investigations at the Pittsburgh Energy Technology Center (PETC). They are: (1) behavior of slurry reactors used for indirect coal liquefaction, and (2) coal liquefaction under supercritical conditions. The current status of each of these tasks is summarized in this report.
Non-destructive methods for measuring the remaining anticorrosive or antioxidative ability of coatings are investigated. For anticorrosive chromium coatings the increasing ferromagnetism caused by loss of chromium is measured by a permeability probe. Measured values on blades after operation are correlated with the progress of corrosion as determined by metallographic methods. For antioxidative aluminum coatings the diminishing layer thickness is taken as indication for the exhaustion of their protection ability. The layer thickness is measured eddy current probes, especially developed for this application.
Bacterial plasmids contain specific genes for resistances to toxic heavy metal ions including Ag+, AsO2-, AsO4(3-), Cd2+, Co2+, CrO4(2-), Cu2+, Hg2+, Ni2+, Pb2+, Sb3+, and Zn2+. Recent progress with...Full Text Available
Ocular and urogenital tract infections with Chlamydia trachomatis can progress to chronic inflammatory diseases that produce blindness and tubal infertility. The pathophysiology of these chronic disease...Full Text Available
Research continued on low severity coal liquefaction. Research using high temperature infrared of cyclic olefins progressed well during this quarter. Several fluorinated solvents were found that provide a high temperature medium for isotetralin and its aromatic and aliphatic analogues.
BackgroundMicroRNAs (miRNAs) are important regulators that play key roles in tumorigenesis and tumor progression. A previous report has shown that let-7 family members can act as...Full Text Available
A cryostat is described that was developed for irradiating a number of small metal specimens with a high beamcurrent of heavy particles at liquid nitrogen temperature. The specimens, which are mounted on a block, are taken out of the cryostat after irradiation and subsequently annealed in a temperature bath. The progress of annealing is followed by measuring the change in electrical resistivity of the specimens in liquid helium. (auth)
Brief summaries of research work are presented in the following section: overview of the ORNL Instrumentation and Controls Division activities; new developments and methods; reactor instrumentation and controls; measurement and control engineering; electronic engineering; maintenance; studies; services; and development; and division achievements.
This issue of the newsletter on Engineering Design Activities (EDA) for the ITER Tokamak project contains a report on Second International Industries' Liaison meeting which was held in Tokyo on 2-4 April 1997 (by Y. Kaneki, JAIF, Japan); an overview report on the Blanket project (by A. Cardella, I.Ioki (ITER Central Team), W. Daenner (EU Home Team)); and a progress report on microwave reflectometry (by J. Sanchez, Madrid, Spain).
... Social Capital Social capital describes circumstances in which individuals and organisations can use membership in groups and networks to secure benefits. Connections within and between networks reinforce the belief that these social networks have a value and can be used as a platform for further social progress. In this light, natural capital and social capital are closely related, and policies that build or destroy one often build ...
The workshop focused on strategies for promoting and developing engineering level transonic flutter prediction techniques. The technology of transonic aerodynamics is currently undergoing rapid development. Significant progress is being made to solve the inherently nonlinear equations describing unsteady motions of wings in transonic flow, while the availability of reliable and efficient computational methods will greatly enhance the ability to predict the aeroelastic behavior of modern aircraft operating under transonic flow conditions.
For most of the history of binary star astronomy, systems have been classified largely on the basis of how they were discovered and qualitative appearance of their spectra and light curves. Present understanding of single and double star evolution has now progressed to the point where most of the classes previously identified, and some new ones, can be arranged into evolutionary sequences, depending primarily on the initial masses and separation of the component stars.
Although human T-cell lymphotropic virus type I (HTLV-I) is the etiologic agent of adult T-cell leukemia/lymphoma (ATL), the role of viral gene expression in the progression to and maintenance of the...Full Text Available
Research programs from the following sections and programs are summarized: aquatic ecology, environmental resources, earth sciences, terrestrial ecology, advanced fossil energy program, toxic substances program, environmental impacts program, biomass, low-level waste research and development program, US DOE low-level waste management program, and waste isolation program.
The electrochemical oxidation as a method to destroy drug residues like Aspirin {sup trademark}, tetracycline or gentamicin in water was investigated with C-Anode (modified by manganese oxides) and Pt Anode. The mechanism of Aspirin {sup trademark} and tetracycline oxidation and the influence of the biocide effect was observed using GC-MS and three different microbiological tests. In general the biological availability increases with progressive oxidation of the antibiotics. (orig.)
Amyloid-β (Aβ) deposits have been identified as key players in the progression of Alzheimer’s disease (AD). Recent evidence indicates that the deposits probably precede...Full Text Available
The report gives results of the first 3 years of study to determine environmentally sound methods for disposing of wastes from nonregenerable flue gas desulfurization systems. Untreated and treated wastes from seven different scrubbers at eastern and western plants, using lime, l...
ERDA's coal liquefaction program is reviewed, especially the progress with several pilot plant operations. Other items involve the possible recovery of organic chemicals from coal liquids, the filtration of coal liquids, some experiments on hydrogenation and carbonization, and renovation of the Cresap materials and equipment test facility. (LTN)
IntroductionMeniscal injury is a risk factor for the development and progression of knee osteoarthritis, yet little is known about risk factors for meniscal pathology. Joint loading...Full Text Available
DescriptionRemote sensing of the sea surface from satellites in near-polar orbits has contributed greatly to our understanding of the links between physical and biological processes in marine systems. However most of this progress has been made in open oceanic waters or major upwelling areas, and many unresolved problems are encountered in coastal regions and shelf seas. In these optically complex waters, quantitative remote sensing requires a more sophisticated interpretation strategy than that implemente [continued...
In clinical situations where a diagnostic real-time PCR assay is not sensitive enough, leading to low or falsely negative results, or where detection earlier in a disease progression would benefit the...Full Text Available
This report summarizes activities of the Amarillo National Resource Center for Plutonium during the quarter. The report describes the Electronic Resource Library; DOE support activities; current and future environmental health and safety programs; pollution prevention and pollution avoidance; communication, education, training, and community involvement programs; and nuclear and other material studies, including plutonium storage and disposition studies.
Programs in coal research by the Pittsburgh Energy Technology Center are discussed. Topics include: Coal Science and Chemistry, Coal Liquefaction, Alternative Fuels, Coal Preparation, Combustion, MHD Program, Flue Gas Cleanup, Environmental Coordination, and Technology Transfer. (CBS)
Studies in advanced coal research are presented. Included are the following: coal science programs; coal preparation and combustion kinetics; advanced technology in liquefaction, including direct and indirect liquefaction; alternative fuels; advanced combustion technology; flue gas cleanup; environmental coordination, technology transfer, and clean coal demonstration program. (CBS)