WorldWideScience
1

Insights into Genome Plasticity and Pathogenicity of the Plant Pathogenic Bacterium Xanthomonas campestris pv. vesicatoria Revealed by the Complete Genome Sequence  

UK PubMed Central (United Kingdom)

The gram-negative plant-pathogenic bacterium Xanthomonas campestris pv. vesicatoria is the causative agent of bacterial spot disease in pepper and tomato plants, which leads to economically...Full Text Available

2005-11-01

2

Justice and the Human Genome Project  

Energy Technology Data Exchange (ETDEWEB)

Most of the essays gathered in this volume were first presented at a conference, Justice and the Human Genome, in Chicago in early November, 1991. The goal of the, conference was to consider questions of justice as they are and will be raised by the Human Genome Project. To achieve its goal of identifying and elucidating the challenges of justice inherent in genomic research and its social applications the conference drew together in one forum members from academia, medicine, and industry with interests divergent as rate-setting for insurance, the care of newborns, and the history of ethics. The essays in this volume address a number of theoretical and practical concerns relative to the meaning of genomic research.

1992-01-01

3

Massive turnover of functional sequence in human and other mammalian genomes  

UK PubMed Central (United Kingdom)

Despite the availability of dozens of animal genome sequences, two key questions remain unanswered: First, what fraction of any species' genome confers biological function, and second, are apparent...Full Text Available

2010-10-01

4

Analysis of the Type IV Fimbrial-Subunit Gene fimA of Xanthomonas hyacinthi: Application in PCR-Mediated Detection of Yellow Disease in Hyacinths  

UK PubMed Central (United Kingdom)

A sensitive and specific detection method was developed for Xanthomonas hyacinthi; this method was based on amplification of a subsequence of the type IV fimbrial-subunit gene fimA...Full Text Available

2001-02-01

5

Development and Application of Pathovar-Specific Monoclonal Antibodies That Recognize the Lipopolysaccharide O Antigen and the Type IV Fimbriae of Xanthomonas hyacinthi  

UK PubMed Central (United Kingdom)

The objective of this study was to develop a specific immunological diagnostic assay for yellow disease in hyacinths, using monoclonal antibodies (MAbs). Mice were immunized with a crude cell wall preparation...Full Text Available

1999-09-01

6

Regulation and secretion of Xanthomonas virulence factors  

British Library Electronic Table of Contents (United Kingdom)

Abstract Plant pathogenic bacteria of the genus Xanthomonas cause a variety of diseases in economically important monocotyledonous and dicotyledonous crop plants worldwide. Successful infection and bacterial multiplication in the host tissue often depend on the virulence factors secreted including adhesins, polysaccharides, LPS and degradative enzymes. One of the key pathogenicity factors is the type III secretion system, which injects effector proteins into the host cell cytosol to manipulate plant cellular processes such as basal defense to the benefit of the pathogen. The coordinated expression of bacterial virulence factors is orchestrated by quorum-sensing pathways, multiple two-component systems and transcriptional regulators such as Clp, Zur, FhrR, HrpX and HpaR. Furthermore, virule...

2010-01-01

7

Growth promotion and induction of resistance in tomato plant against Xanthomonas euvesicatoria and Alternaria solani by Trichoderma spp.  

British Library Electronic Table of Contents (United Kingdom)

In tomato crop, the induction of resistance emerges as an important alternative for achieving the reduction of chemicals in disease control. This study aimed to evaluate the ability of 28 Trichoderma isolates to promote the growth of tomato seedlings and to induce systemic resistance (ISR) against Xanthomonas euvesicatoria and Alternaria solani, the causal agents of bacterial spot and early blight, respectively. Twelve isolates promoted the increase of plant dry matter mass (DMM) above 100%, showing the great potential of these strains. All isolates were able to colonize the root system of tomato plants. The plant growth-promoting isolates were further evaluated for potential elicitation of ISR. Treatment of the soil with all Trichoderma isolates provided protection in tomato plants from 2...

2011-01-01

8

Conference excitement recalled by "CERN courier" report  

CERN Multimedia

Conference excitement recalled by "CERN courier" report

1962-01-01

9

Structural and operational complexity of the Geobacter sulfurreducens genome  

UK PubMed Central (United Kingdom)

Prokaryotic genomes can be annotated based on their structural, operational, and functional properties. These annotations provide the pivotal scaffold for understanding cellular functions on a genome-scale,...Full Text Available

2010-09-01

10

Intrapopulation Genome Size Dynamics in Festuca pallens  

UK PubMed Central (United Kingdom)

Background and AimsIt is well known that genome size differs among species. However, information on the variation and dynamics of genome size in wild populations and on the early...Full Text Available

2008-10-01

11

Whole-genome shotgun assembly and comparison of human genome assemblies  

UK PubMed Central (United Kingdom)

We report a whole-genome shotgun assembly (called WGSA) of the human genome generated at Celera in 2001. The Celera-generated shotgun data set consisted of 27 million sequencing reads organized in pairs...Full Text Available

2004-02-17

13

The complete mitochondrial genome of the stomatopod crustacean Squilla mantis  

UK PubMed Central (United Kingdom)

BackgroundAnimal mitochondrial genomes are physically separate from the much larger nuclear genomes and have proven useful both for phylogenetic studies and for understanding genome...Full Text Available

15

Genomics - from Neanderthals to high-throughput sequencing  

UK PubMed Central (United Kingdom)

A report on 'The Biology of Genomes' meeting, Cold Spring Harbor, USA, 10-14 May 2006.

2006-01-01

16

Designing a Truly Integrated (Onsite and Online) Conference: Concept, Processes, Solutions  

CERN Document Server

Web conferencing tools have entered the mainstream of business applications. Using web conferencing for IEEE conferences has a good potential of adding value to both organizers and participants. Authors propose a concept of Truly Integrated Conference (TIC) according to which a multi-point worldwide-distributed network of conference online authors/participants will enhance the standard (centralized) IEEE conference model, which requires attendance of the participants in person at the main conference location. The concept entails seamless integration of the onsite and online conference systems, including data/presentation, video, audio channels. Benefits and challenges of the TIC concept are analyzed. Requirements to the web conferencing system capable of supporting the TIC conference are presented and reviewed against commercial web ...

2010-01-01

17

Proceedings of the 8th ocean energy conference  

Energy Technology Data Exchange (ETDEWEB)

Separate abstracts were prepared for 62 papers in this volume of conference proceedings. Two other papers were previously abstracted for EDB. (LEW)

1981-06-01

18

Perspectives in radiation and health: reflections on the International Conference in Beer Sheva.  

UK PubMed Central (United Kingdom)

Insofar as international conferences reflect the state of development of the subject under discussion, they provide an opportunity to question, at a rather fundamental level, the direction of and progress...Full Text Available

1997-12-01

19

Corps of Engineers Structural Engineering Conference Held ...  

Science.gov (United States)

... CI Appendix D: Conference Attendees ..... D1 Appendix E: Structural Steel Connection Design on Federal Projects ..... El iv ...

1992-12-01

20

Cardioprotection conferred by exercise training is blunted by blockade of the opioid system  

UK PubMed Central (United Kingdom)

OBJECTIVES:To investigate the effect of opioid receptor blockade on the myocardial protection conferred by chronic exercise and to compare exercise training with different strategies...Full Text Available

2011-01-01

21

Complexation of nitrogen and sulphur donor Schiff's base ligand to Cr(III) and Ni(II) metal ions: Synthesis, spectroscopic and antipathogenic studies  

British Library Electronic Table of Contents (United Kingdom)

2,6-Diacetyl pyridine based ligand was synthesized by the reaction of 2,6-diacetyl pyridine with thiocarbohydrazide in presence of acetic acid. The coordination compounds with Cr(III) and Ni(II) metal ions having [Cr(L)X]X2 and [Ni(L)X]X compositions (where L=ligand and X=NO3^-, Cl^- and CH3COO^-) were synthesized and characterized by physicochemical and spectral studies. The studies like elemental analyses, molar conductance measurements, magnetic susceptibility measurements, IR, UV-Vis, NMR, mass and EPR reveal that the complexes are octahedral. The compounds were examined against the pathogenic fungal and bacterial strains like Alternaria brassicae, Aspergillus niger, Fusarium oxysporum, Xanthomonas compestris and Pseudomonas aeruginosa. A. niger causes the diseases Apergillosis and Oto...

2011-01-01

22

The mode and tempo of genome size evolution in eukaryotes  

UK PubMed Central (United Kingdom)

Eukaryotic genome size varies over five orders of magnitude; however, the distribution is strongly skewed toward small values. Genome size is highly correlated to a number of phenotypic traits, suggesting...Full Text Available

2007-05-01

23

Sequence space coverage, entropy of genomes and the potential to detect non-human DNA in human samples  

UK PubMed Central (United Kingdom)

BackgroundGenomes store information for building and maintaining organisms. Complete sequencing of many genomes provides the opportunity to study and compare global information properties...Full Text Available

24

Improving the Arabidopsis genome annotation using maximal transcript alignment assemblies  

UK PubMed Central (United Kingdom)

The spliced alignment of expressed sequence data to genomic sequence has proven a key tool in the comprehensive annotation of genes in eukaryotic genomes. A novel algorithm was developed to assemble...Full Text Available

2003-10-01

25

Genome Sequence and Comparative Analysis of the Solvent-Producing Bacterium Clostridium acetobutylicum  

UK PubMed Central (United Kingdom)

The genome sequence of the solvent-producing bacterium Clostridium acetobutylicum ATCC 824 has been determined by the shotgun approach. The genome consists of a 3.94-Mb chromosome and...Full Text Available

2001-08-01

26

Full genome gene expression analysis of the heat stress response in Drosophila melanogaster  

UK PubMed Central (United Kingdom)

The availability of full genome sequences has allowed the construction of microarrays, with which screening of the full genome for changes in gene expression is possible. This method can provide a wealth...Full Text Available

2005-10-01

27

Extensive synteny conservation of holocentric chromosomes in Lepidoptera despite high rates of local genome rearrangements  

UK PubMed Central (United Kingdom)

The recent assembly of the silkworm Bombyx mori genome with 432 Mb on 28 holocentric chromosomes has become a reference in the genomic analysis of the very diverse Order of Lepidoptera....Full Text Available

2010-04-27

28

A DNA transposon-based approach to validate oncogenic mutations in the mouse  

UK PubMed Central (United Kingdom)

Large-scale cancer genome projects will soon be able to sequence many cancer genomes to comprehensively identify genetic changes in human cancer. Genome-wide association studies have also identified...Full Text Available

2008-12-16

29

A Computational Framework Discovers New Copy Number Variants with Functional Importance  

UK PubMed Central (United Kingdom)

Structural variants which cause changes in copy numbers constitute an important component of genomic variability. They account for 0.7% of genomic differences in two individual genomes, of which...Full Text Available

31

44th Canadian geotechnical conference: Preprint volume. 44th conference canadienne de geotechnique  

Energy Technology Data Exchange (ETDEWEB)

A conference on geotechnics presented papers on soil properties, soil liquefaction, slope stability, pile foundations, numerical modelling, engineering geology, rock mechanics, cold regions engineering, oil sands, irrigation, environmental engineering, geosynthetics, and geotechnical case histories. Separate abstracts have been prepared for 29 papers from the conference.

1991-01-01

33

Widespread duplications in the genomes of laboratory stocks of Dictyostelium discoideum  

UK PubMed Central (United Kingdom)

BackgroundDuplications of stretches of the genome are an important source of individual genetic variation, but their unrecognized presence in laboratory organisms would be a confounding...Full Text Available

2008-01-01

34

Time-dependent ARMA modeling of genomic sequences  

UK PubMed Central (United Kingdom)

BackgroundOver the past decade, many investigators have used sophisticated time series tools for the analysis of genomic sequences. Specifically, the correlation of the nucleotide...Full Text Available

35

Methods in DNA methylation profiling  

UK PubMed Central (United Kingdom)

Metastable and somatically heritable patterns of DNA methylation provide an important level of genomic regulation. In this article, we review methods for analyzing these genome-wide epigenetic...Full Text Available

2009-12-01

36

Genomics of human longevity  

UK PubMed Central (United Kingdom)

In animal models, single-gene mutations in genes involved in insulin/IGF and target of rapamycin signalling pathways extend lifespan to a considerable extent. The genetic, genomic and epigenetic influences...Full Text Available

2011-01-12

37

Genomic view of the evolution of the complement system  

UK PubMed Central (United Kingdom)

The recent accumulation of genomic information of many representative animals has made it possible to trace the evolution of the complement system based on the presence or absence of each complement...Full Text Available

2006-09-01

38

Genomic imprinting and the social brain  

UK PubMed Central (United Kingdom)

Genomic imprinting refers to the parent-of-origin-specific epigenetic marking of a number of genes. This epigenetic mark leads to a bias in expression between maternally and paternally inherited imprinted...Full Text Available

2006-12-29

39

Genetics, Genomics, and Molecular Biology  

Science.gov (United States)

Genetics, Genomics, and Molecular Biology USGS scientists develop and integrate new genetic and molecular techniques into systematic analyses to describe individuals and populations of fish .....

40

Enzymatic engineering of the porcine genome with transposons and recombinases  

UK PubMed Central (United Kingdom)

BackgroundSwine is an important agricultural commodity and biomedical model. Manipulation of the pig genome provides opportunity to improve production efficiency, enhance disease...Full Text Available

41

Comparative and phylogenomic studies on the mitochondrial genomes of Pentatomomorpha (Insecta: Hemiptera: Heteroptera)  

UK PubMed Central (United Kingdom)

BackgroundNucleotide sequences and the gene arrangements of mitochondrial genomes are effective tools for resolving phylogenetic problems. Hemipteroid insects are known to possess...Full Text Available

42

Cancer gene discovery in mouse and man  

UK PubMed Central (United Kingdom)

AbstractThe elucidation of the human and mouse genome sequence and developments in high-throughput genome analysis, and in computational tools, have made it possible to profile entire...Full Text Available

2009-12-01

44

Interpreting Mammalian Evolution using Fugu Genome Comparisons  

Energy Technology Data Exchange (ETDEWEB)

Comparative sequence analysis of the human and the pufferfish Fugu rubripes (fugu) genomes has revealed several novel functional coding and noncoding regions in the human genome. In particular, the fugu genome has been extremely valuable for identifying transcriptional regulatory elements in human loci harboring unusually high levels of evolutionary conservation to rodent genomes. In such regions, the large evolutionary distance between human and fishes provides an additional filter through which functional noncoding elements can be detected with high efficiency.

2004-04-02

45

WIZARD collaboration : Papers presented at the 24. International Cosmic Ray Conference, August 28-September 8, Rome 1995  

Energy Technology Data Exchange (ETDEWEB)

This report described the papers presented at the 24. International Cosmic Ray Conference held at Rome in 28 August - 8 September 1995

1995-09-01

46

Proceedings of the eighth West Virginia University international mining electrotechnology conference  

Energy Technology Data Exchange (ETDEWEB)

A total of 25 papers were presented at the conference in 6 sessions: illumination and communication; power and safety; knowledge based systems; mine-wide monitoring; instrumentation control and automation; remote sensing and imaging.

1986-01-01

47

Proceedings of the 8th ocean energy conference  

Energy Technology Data Exchange (ETDEWEB)

Separate abstracts were prepared for 60 papers in this volume of conference proceedings. None other papers in the proceedings were previously abstracted for EDB. Also included in the proceedings but not indexed separately are six workshop summaries and a session introduction. (LEW)

1981-06-01

48

12. European fuels conference  

International Nuclear Information System (INIS)

The 12. Annual European Fuels Conference has enabled refiners and fuel developers on March 2011 (8-11). In this work, the lecturers draw the new tendencies and difficulties at which the refining industry will be confronted with. (O.M.)

49

Proceedings of the Canadian Society for Bioengineering CSBE/SCGAB 2009 annual general meeting and technical conference  

Energy Technology Data Exchange (ETDEWEB)

This conference was attended by experts on current issues in engineering of an urban ecosystem, composting, biofuels and green energy. The meeting provided a forum to discuss advances in the application of engineering principles and practices dealing with biological systems for the production of food, bioproducts and energy. The discussions focused on engineering practices in agriculture, forestry, bioresources, biochemistry and biosystems. The 7 technical sessions of the conference were entitled: aquaculture; safety and training; bioprocessing; energy production and biofuels; environment and ecology; soil and water; and development of technologies. The conference feature 58 presentations, of which 9 have been catalogued separately for inclusion in this database. refs., tabs., figs.

2009-07-01

50

Proceedings of the Canadian Society for Bioengineering CSBE/SCGAB 2008 annual meeting  

Energy Technology Data Exchange (ETDEWEB)

This conference provided a forum to discuss advances in the application of bioengineering principles and practices dealing with biological systems for the production of food, bioproducts and energy. The topics of discussion ranged from engineering practices in agriculture, forestry, bioresources, biochemistry and biosystems. The sessions of the conference were entitled: renewable energy; waste management; soil and water; machinery systems; building and storage systems; and bioproducts and food. The conference also featured a workshop on integrated biomass supply and logistics. In addition to 20 posters, the conference featured 67 presentations, of which 3 have been catalogued separately for inclusion in this database. refs., tabs., figs.

2008-07-01

51

Preparation of Papers for AIAA Technical Conferences  

Science.gov (United States)

The estimated parameter covariance matrix is computed from8. ) ( ) 1. 2. T. T. ( ) ( )(. ?. ?. ?. Cov. E. ??. . ?. = . ? ? ? ? ?. ?. = ?. ?. ? ...

52

Mini-conference on Angular Momentum Transport in Laboratory and Nature  

Energy Technology Data Exchange (ETDEWEB)

This paper provides a concise summary of the current status of the research and future perspectives discussed in the Mini-Conference on Angular Momentum Transport in Laboratory and Nature. This Mini-conference, sponsored by the Topical Group on Plasma Astrophysics, was held as part of the American Physical Society's Division of Plasma Physics 2007 Annual Meeting (November 12{16, 2007). This Mini-conference covers a wide range of phenomena happening in fluids and plasmas, either in laboratory or in nature. The purpose of this paper is not to comprehensively review these phenomena, but to provide a starting point for interested readers to refer to related research in areas other than their own.

2008-05-06

53

Lessons from the past and prospects for the future  

Energy Technology Data Exchange (ETDEWEB)

The author presents his impressions of the conference - that is - major lessons as presented in the talks on nonlinearities and their role in condensed matter physics. (WRF)

1986-05-04

54

Integrating phytotechnologies with energy crop production for biofuels  

Science.gov (United States)

Integrating phytotechnologies with energy crop production for biofuels, bioenergy, and bioproducts. In: Sixth International Phytotechnologies Conference ; ...

55

3rd GOES Users' Conference  

Science.gov (United States)

with the support and cooperation of the American Meteorological Society, the Marine Technology Society, the National Aeronautics and Space Administration, the National Institute...

2011-10-08

56

25th Space Simulation Conference. Environmental Testing: The Earth-Space Connection  

Science.gov (United States)

Topics covered include: Methods of Helium Injection and Removal for Heat Transfer Augmentation; The

2008-01-01

57

The evolution of x-ray binaries  

International Nuclear Information System (INIS)

These proceedings represent papers presented at the Astrophysics Conference in Maryland, USA. The topic of the Conference was the evolution of x-ray binaries and the papers encompass a wide range of subjects on x-ray astronomy. There were one hundred eighteen papers presented at the Conference and out of these three have been abstracted for the Energy Science and Technology database.

1993-10-11

58

Research and Evaluation of Advanced Nondestructive Examination (NDE) Methods for Addressing the Challenges of Inspecting Cast Austenitic Stainless Steel (CASS) Piping  

Energy Technology Data Exchange (ETDEWEB)

This Conference paper is for submission to the 7th International Conference on NDE in Relation to Structural Integrity for Nuclear and Pressurized Components, in Yokohama, Japan Specifically, this paper is being presented at this Conference on May 12-14, 2009.

2009-07-01

59

Non-Linear Dose-Response Relationships in Biology, Toxicology and Medicine - An International Conference  

Energy Technology Data Exchange (ETDEWEB)

Conference abstract book contains seven sections: Plenary-4 abstracts; Chemical-9 abstracts; Radiation-7 abstracts; Ultra Low Doses and Medicine-6 abstracts; Biomedical-11 abstracts; Risk Assessment-5 abstracts and Poster Sessions-25 abstracts. Each abstract was provided by the author/presenter participating in the conference.

2002-05-28

60

China Clean Energy Announces Second Quarter 2011 Financial Results on Environmental Expert  

Wastenet

... To participate in the live conference call, please dial the following number five to ten minutes prior to the scheduled conference call time:... International callers should dial +1 (706) 643-0585. When prompted by the operator, mention conference pass code 89461112. ... To access the replay, please dial +1 (855) 859-2056, international callers dial +1 (404) 537-3406, ...

61

2004 Reversible Associations in Structure & Molecular Biology  

Energy Technology Data Exchange (ETDEWEB)

The Gordon Research Conference (GRC) on 2004 Gordon Research Conference on Reversible Associations in Structure & Molecular Biology was held at Four Points Sheraton, CA, 1/25-30/2004. The Conference was well attended with 82 participants (attendees list attached). The attendees represented the spectrum of endeavor in this field coming from academia, industry, and government laboratories, both U.S. and foreign scientists, senior researchers, young investigators, and students.

2005-03-23

62

ECRbase: Database of Evolutionary Conserved Regions, Promoters, and Transcription Factor Binding Sites in Vertebrate Genomes  

Energy Technology Data Exchange (ETDEWEB)

Evolutionary conservation of DNA sequences provides a tool for the identification of functional elements in genomes. We have created a database of evolutionary conserved regions (ECRs) in vertebrate genomes entitled ECRbase that is constructed from a collection of pairwise vertebrate genome alignments produced by the ECR Browser database. ECRbase features a database of syntenic blocks that recapitulate the evolution of rearrangements in vertebrates and a collection of promoters in all vertebrate genomes presented in the database. The database also contains a collection of annotated transcription factor binding sites (TFBS) in all ECRs and promoter elements. ECRbase currently includes human, rhesus macaque, dog, opossum, rat, mouse, chicken, frog, zebrafish, and two pufferfish genomes. It is freely accessible at http://ECRbase.dcode.org.

2006-08-08

63

Proceedings of the Canadian Society for Bioengineering CSBE/SCGAB 2006 national technical conference  

Energy Technology Data Exchange (ETDEWEB)

This conference provided a forum for discussing advances in the application of engineering principles and practices dealing with biological systems for the production of food, bioproducts and energy. The discussions focused on engineering practices in agriculture, forestry, bioresources, biochemistry and biosystems. The sessions of the conference were entitled: renewable energy and biofuels; food and bioproducts; odour and greenhouse gases; soil and water; waste management and bioresiduals; animal welfare and production; grain storage; machinery systems; structures and biocomposites; and, agricultural production. The conference also featured a workshop on modeling material and energy flows through agro-ecosystems. In addition to 22 posters, the conference featured 100 presentations, of which 8 have been catalogued separately for inclusion in this database. refs., tabs., figs.

2006-07-01

64

Whole-genome cancer analysis as an approach to deeper understanding of tumour biology  

UK PubMed Central (United Kingdom)

Recent advances in DNA sequencing technology are providing unprecedented opportunities for comprehensive analysis of cancer genomes, exomes, transcriptomes, as well as epigenomic components. The integration...Full Text Available

2010-01-19

65

Using Regulatory and Epistatic Networks to Extend the Findings of a Genome Scan: Identifying the Gene Drivers of Pigmentation in Merino Sheep  

UK PubMed Central (United Kingdom)

Extending genome wide association analysis by the inclusion of gene expression data may assist in the dissection of complex traits. We examined piebald, a pigmentation phenotype in both human and Merino...Full Text Available

66

Transcriptional mapping of the 3' end of the bovine syncytial virus genome.  

UK PubMed Central (United Kingdom)

The bovine syncytial virus, a member of the retroviral subfamily Spumavirinae, causes a persistent, asymptomatic infection in cattle. Nucleotide sequence analysis of the viral genome revealed two overlapping...Full Text Available

1994-02-01

67

The European sea bass Dicentrarchus labrax genome puzzle: comparative BAC-mapping and low coverage shotgun sequencing  

UK PubMed Central (United Kingdom)

BackgroundFood supply from the ocean is constrained by the shortage of domesticated and selected fish. Development of genomic models of economically important fishes should assist...Full Text Available

68

Targeted plasmid integration into the human genome by an engineered zinc-finger recombinase  

UK PubMed Central (United Kingdom)

The development of new methods for gene addition to mammalian genomes is necessary to overcome the limitations of conventional genetic engineering strategies. Although a variety of DNA-modifying enzymes...Full Text Available

2011-09-01

69

Synthesis and degradation of dinoflagellate plastid-encoded psbA proteins are light-regulated, not circadian-regulated  

UK PubMed Central (United Kingdom)

In many dinoflagellate species, the plastid genome has been proposed to exist as a limited number of single-gene minicircles, and many genes normally found in the plastid genome are nuclear-encoded....Full Text Available

2005-02-22

70

Replication Stress Induces Genome-wide Copy Number Changes in Human Cells that Resemble Polymorphic and Pathogenic Variants  

UK PubMed Central (United Kingdom)

Copy number variants (CNVs) are an important component of genomic variation in humans and other mammals. Similar de novo deletions and duplications, or copy number changes (CNCs), are now known to be...Full Text Available

2009-03-13

71

Reciprocal Silencing, Transcriptional Bias and Functional Divergence of Homeologs in Polyploid Cotton (Gossypium)  

UK PubMed Central (United Kingdom)

Polyploidy is an important force in the evolution of flowering plants. Genomic merger and doubling induce an extensive array of genomic effects, including immediate and long-term alterations in the...Full Text Available

2009-06-01

72

Rai1 duplication causes physical and behavioral phenotypes in a mouse model of dup(17)(p11.2p11.2)  

UK PubMed Central (United Kingdom)

Genomic disorders are conditions that result from DNA rearrangements, such as deletions or duplications. The identification of the dosage-sensitive gene(s) within the rearranged genomic interval is...Full Text Available

2006-11-01

73

Rab protein evolution and the history of the eukaryotic endomembrane system  

UK PubMed Central (United Kingdom)

Spectacular increases in the quantity of sequence data genome have facilitated major advances in eukaryotic comparative genomics. By exploiting homology with classical model organisms, this makes possible...Full Text Available

2010-10-01

74

Presence of two independent chromosomes in the Brucella melitensis 16M genome.  

UK PubMed Central (United Kingdom)

Mapping the restriction fragments of the Brucella melitensis 16M genome with a new restriction endonuclease, PacI, which cut the DNA into only eight fragments, indicated that this species contains two...Full Text Available

1993-02-01

75

Parallel Loss of Plastid Introns and Their Maturase in the Genus Cuscuta  

UK PubMed Central (United Kingdom)

Plastid genome content and arrangement are highly conserved across most land plants and their closest relatives, streptophyte algae, with nearly all plastid introns having invaded the genome in their...Full Text Available

76

Nucleocapsid and Matrix Protein Contributions to Selective Human Immunodeficiency Virus Type 1 Genomic RNA Packaging  

UK PubMed Central (United Kingdom)

The nucleocapsid protein (NC) of retroviruses plays a major role in genomic RNA packaging, and some evidence has implicated the matrix protein (MA) of certain retroviruses in viral RNA binding. To further...Full Text Available

1998-03-01

77

Natural mutagenesis of human genomes by endogenous retrotransposons  

UK PubMed Central (United Kingdom)

SUMMARYTwo abundant classes of mobile elements, namely Alu and L1 elements, continue to generate new retrotransposon insertions in human genomes. Estimates suggest that these...Full Text Available

2010-06-25

78

Molecular characterization of a Chinese variant of the Flury-LEP strain  

UK PubMed Central (United Kingdom)

The entire genome of rabies virus vaccine strain Flury-LEP-C, a Chinese variant of the rabies virus vaccine strain Flury-LEP, was sequenced. The overall length of the genome of Flury-LEP-C strain was...Full Text Available

79

Mobilizing diversity: transposable element insertions in genetic variation and disease  

UK PubMed Central (United Kingdom)

Transposable elements (TEs) comprise a large fraction of mammalian genomes. A number of these elements are actively jumping in our genomes today. As a consequence, these insertions provide a source...Full Text Available

80

Large-scale cross-species oncogenomics identifies candidate oncogenes and tumor suppressor genes  

UK PubMed Central (United Kingdom)

While genomic alterations identified in human tumors using techniques such as comparative genomic hybridisation (CGH) may be recurrent, they frequently encompass large regions, in some cases...Full Text Available

2010-02-01

81

Isolation of BAC Clones Containing Conserved Genes from Libraries of Three Distantly Related Moths: A Useful Resource for Comparative Genomics of Lepidoptera  

UK PubMed Central (United Kingdom)

Lepidoptera, butterflies and moths, is the second largest animal order and includes numerous agricultural pests. To facilitate comparative genomics in Lepidoptera, we isolated BAC clones containing...Full Text Available

2011-01-01

82

Integration of metabolic databases for the reconstruction of genome-scale metabolic networks  

UK PubMed Central (United Kingdom)

BackgroundGenome-scale metabolic reconstructions have been recognised as a valuable tool for a variety of applications ranging from metabolic engineering to evolutionary studies....Full Text Available

83

Impact of genetic changes to the CRPV genome and their application to the study of pathogenesis in vivo  

UK PubMed Central (United Kingdom)

The cottontail rabbit papillomavirus (CRPV)/rabbit model has been used to study oncogenicity and immunogenicity of different antigens from the papillomavirus genome and has therefore served...Full Text Available

2007-02-20

84

Identifying related L1 retrotransposons by analyzing 3' transduced sequences  

UK PubMed Central (United Kingdom)

BackgroundA large fraction of the human genome is attributable to L1 retrotransposon sequences. Not only do L1s themselves make up a significant portion of the genome, but L1-encoded...Full Text Available

2003-01-01

85

Genomic cloning and characterization of a ricin gene from Ricinus communis.  

UK PubMed Central (United Kingdom)

A genomic clone that specifies a single polypeptide precursor for ricin, a toxic lectin of Ricinus communis (castor bean), was isolated, sequenced and Sl mapped. The gene encodes a 64 kDa precursor...Full Text Available

1985-11-25

86

Genomes are covered with ubiquitous 11 bp periodic patterns, the "class A flexible patterns"  

UK PubMed Central (United Kingdom)

BackgroundThe genomes of prokaryotes and lower eukaryotes display a very strong 11 bp periodic bias in the distribution of their nucleotides. This bias is present throughout a given...Full Text Available

87

Genome-wide detection and characterization of positive selection in human populations  

UK PubMed Central (United Kingdom)

With the advent of dense maps of human genetic variation, it is now possible to detect positive natural selection across the human genome. Here we report an analysis of over 3 million polymorphisms...Full Text Available

2007-10-18

88

Genome-wide characterization of simple sequence repeats in cucumber (Cucumis sativus L.)  

UK PubMed Central (United Kingdom)

BackgroundCucumber, Cucumis sativus L. is an important vegetable crop worldwide. Until very recently, cucumber genetic and genomic resources, especially molecular...Full Text Available

89

Genome-Wide Identification and Evolutionary Analysis of the Animal Specific ETS Transcription Factor Family  

UK PubMed Central (United Kingdom)

The ETS proteins are a family of transcription factors (TFs) that regulate a variety of biological processes. We made genome-wide analyses to explore the classification of the ETS gene family. We identified...Full Text Available

90

Genome size and wing parameters in passerine birds  

UK PubMed Central (United Kingdom)

Despite their status as the most speciose group of terrestrial vertebrates, birds exhibit the smallest and least variable genome sizes among tetrapods. It has been suggested that this is because powered...Full Text Available

2009-01-07

91

Genetic susceptibility to systemic lupus erythematosus in the genomic era  

UK PubMed Central (United Kingdom)

Our understanding of the genetic basis of systemic lupus erythematosus (SLE) has been rapidly advanced using large-scale, case–control, candidate gene studies as well as genome-wide...Full Text Available

2010-12-01

92

Estimating Missing Heritability for Disease from Genome-wide Association Studies  

UK PubMed Central (United Kingdom)

Genome-wide association studies are designed to discover SNPs that are associated with a complex trait. Employing strict significance thresholds when testing individual SNPs avoids false positives at...Full Text Available

2011-03-11

93

Epitope tagging of endogenous proteins for genome wide Chromatin immunoprecipitation analysis  

UK PubMed Central (United Kingdom)

The development of chromatin immunoprecipitation methods coupled with DNA microarray (ChIP-chip) technology has enabled genome-wide identification of cis-DNA regulatory elements to which transcription...Full Text Available

2009-01-01

94

Dynamic Rearrangements Determine Genome Organization and Useful Traits in Soybean1[C][W  

UK PubMed Central (United Kingdom)

Soybean (Glycine max) is a paleopolyploid whose genome has gone through at least two rounds of polyploidy and subsequent diploidization events. Several studies have investigated the...Full Text Available

2009-11-01

95

Completely phased genome sequencing through chromosome sorting  

UK PubMed Central (United Kingdom)

The two haploid genome sequences that a person inherits from the two parents represent the most fundamentally useful type of genetic information for the study of heritable diseases and the development...Full Text Available

2011-01-04

96

Complete plastid genome sequences suggest strong selection for retention of photosynthetic genes in the parasitic plant genus Cuscuta  

UK PubMed Central (United Kingdom)

BackgroundPlastid genome content and protein sequence are highly conserved across land plants and their closest algal relatives. Parasitic plants, which obtain some or all of their...Full Text Available

97

Comparative genomics of the bacterial genus Listeria: Genome evolution is characterized by limited gene acquisition and limited gene loss  

UK PubMed Central (United Kingdom)

BackgroundThe bacterial genus Listeria contains pathogenic and non-pathogenic species, including the pathogens L. monocytogenes and L. ivanovii,...Full Text Available

98

Bunyamwera virus can repair both insertions and deletions during RNA replication  

UK PubMed Central (United Kingdom)

The genomic termini of RNA viruses contain essential cis-acting signals for such diverse functions as packaging, genome translation, mRNA transcription, and RNA replication, and thus...Full Text Available

2010-06-01

99

Biophysical characterization of recombinant proteins: A key to higher structural genomics success  

UK PubMed Central (United Kingdom)

Hundreds of genomes have been successfully sequenced to date, and the data are publicly available. At the same time, the advances in large-scale expression and purification of recombinant proteins have...Full Text Available

2010-10-01

100

Behavioral genomics of honeybee foraging and nest defense  

UK PubMed Central (United Kingdom)

The honeybee has been the most important insect species for study of social behavior. The recently released draft genomic sequence for the bee will accelerate honeybee behavioral genetics. Although...Full Text Available

2007-04-01

101

Avian Nephritis Virus (ANV) as a New Member of the Family Astroviridae and Construction of Infectious ANV cDNA  

UK PubMed Central (United Kingdom)

The complete RNA genome of the avian nephritis virus (ANV) associated with acute nephritis in chickens has been molecularly cloned and sequenced. Excluding the poly(A) tail, the genome comprises 6,927...Full Text Available

2000-09-01

102

Analysis of illegitimate genomic integration mediated by zinc-finger nucleases: implications for specificity of targeted gene correction  

UK PubMed Central (United Kingdom)

BackgroundFormation of site specific genomic double strand breaks (DSBs), induced by the expression of a pair of engineered zinc-finger nucleases (ZFNs), dramatically increases the...Full Text Available

103

A proposal to sequence the genome of a garter snake (Thamnophis sirtalis)  

UK PubMed Central (United Kingdom)

Here we develop an argument in support of sequencing a garter snake (Thamnophis sirtalis) genome, and outline a plan to accomplish this. This snake is a common, widespread, nonvenomous...Full Text Available

104

A haplotype map of the human genome  

UK PubMed Central (United Kingdom)

Inherited genetic variation has a critical but as yet largely uncharacterized role in human disease. Here we report a public database of common variation in the human genome: more than one million...Full Text Available

2005-10-27

105

A genome-wide survey of Major Histocompatibility Complex (MHC) genes and their paralogues in zebrafish  

UK PubMed Central (United Kingdom)

BackgroundThe genomic organisation of the Major Histocompatibility Complex (MHC) varies greatly between different vertebrates. In mammals, the classical MHC consists of a large number...Full Text Available

106

A Marker-Dense Physical Map of the Bradyrhizobium japonicum Genome  

UK PubMed Central (United Kingdom)

Bacterial artificial chromosome (BAC) clones are effective mapping and sequencing reagents for use with a wide variety of small and large genomes. This report describes the development of a physical...Full Text Available

2001-08-01

107

Steam turbines and operation of steam turbines 2008. Lectures; Dampfturbinen und Dampfturbinenbetrieb 2008. Vortraege  

Energy Technology Data Exchange (ETDEWEB)

This year, the VGB Conference 'Steam Turbines and Operation of Steam Turbines 2008' will take place at the Deutsches Haus in Flensburg. By offering the possibility for exchanging experience, this conference aims to also ensure steam turbine operation with high availability and high efficiency in the future. The changing situation of the market and the responses on the parts of the manufacturers and the operators, as well as the responses of the entire service section to this, show that such an exchange of experience is of utmost importance. This year, the conference will focus on the following topics: - reviews - damage - further developing testing methods - monitoring steam turbines - modernising old steam turbines - new products - new developments in the condenser pipe sector. As in previous years, our Co-operation partners will present themselves at a technical exhibition which will be part of the ...

2008-07-01

108

Genomic Careers: Interactive Videos  

Medline Plus

... the nature of DNA testing. 07:56 - President / CEO of a Biotechnology / Pharmaceutical Company - Sherri Bale President ...

109

Exons, Introns and Talking Genes: The Sience Behind the Human Genome Project  

Energy Technology Data Exchange (ETDEWEB)

This book presents in simple terms the basis of molecular genetics and how it is used to obtain an understanding of the human genome. The author's central focus is the transistion of genetics from statistics to experimental manipulations, and he offers analogies that help readers visualize the genome, thereby avoiding conventional scientific presentations. He illustrates how genetics is used in scientific laboratories, in courtrooms, and in hospitals. Little is presented about the complex social and ethical issues raised by the Human Genome project.

1993-01-01

110

Genome-Wide Association Study SNPs in the Human Genome Diversity Project Populations: Does Selection Affect Unlinked SNPs with Shared Trait Associations?  

UK PubMed Central (United Kingdom)

Genome-wide association studies (GWAS) have identified more than 2,000 trait-SNP associations, and the number continues to increase. GWAS have focused on traits with potential consequences for human...Full Text Available

2011-01-01

111

Genome structure of cotton revealed by a genome-wide SSR genetic map constructed from a BC1 population between gossypium hirsutum and G. barbadense  

UK PubMed Central (United Kingdom)

BackgroundCotton, with a large genome, is an important crop throughout the world. A high-density genetic linkage map is the prerequisite for cotton genetics and breeding. A genetic...Full Text Available

112

Survey and analysis of simple sequence repeats in the Laccaria bicolor genome, with development of microsatellite markers  

Energy Technology Data Exchange (ETDEWEB)

It is becoming clear that simple sequence repeats (SSRs) play a significant role in fungal genome organization, and they are a large source of genetic markers for population genetics and meiotic maps. We identified SSRs in the Laccaria bicolor genome by in silico survey and analyzed their distribution in the different genomic regions. We also compared the abundance and distribution of SSRs in L. bicolor with those of the following fungal genomes: Phanerochaete chrysosporium, Coprinopsis cinerea, Ustilago maydis, Cryptococcus neoformans, Aspergillus nidulans, Magnaporthe grisea, Neurospora crassa and Saccharomyces cerevisiae. Using the MISA computer program, we detected 277,062 SSRs in the L. bicolor genome representing 8% of the assembled genomic sequence. Among the analyzed basidiomycetes, L. bicolor exhibited the highest SSR density although no correlation ...

2011-01-01

113

Proceedings of the 1995 oil heat technology conference and workshop  

Energy Technology Data Exchange (ETDEWEB)

This report documents the Proceedings of the 1995 Oil Heat Technology Conference and Workshop, held on March 22-23 at Brookhaven National Laboratory (BNL), and sponsored by the U.S. Department of Energy - Office of Building Technologies (DOE-OBT), in cooperation with the Petroleum Marketers Association of America. This Conference, which was the ninth held since 1984, is a key technology transfer activity supported by the ongoing Combustion Equipment Technology (Oil-Heat R&D) program at BNL, and is aimed at providing a forum for the exchange of information among international researchers, engineers, manufacturers, and marketers of oil-fired space-conditioning equipment. The objectives of the Conference were to: (1) Identify and evaluate the state-of-the-art and recommend new initiatives for higher efficiency, a cleaner environment, and to satisfy consumer needs cost-effectively, reliably, and safely; (2) Foster ...

1995-04-01

114

Proceedings of the eleventh thematic conference - geologic remote sensing: Practical solutions for real world problems. Volume 2  

Energy Technology Data Exchange (ETDEWEB)

This document contains the Proceedings of the Eleventh Thematic Conference Geologic Remote Sensing (Volume II). The conference was held February 27-29, 1996 in Las Vegas, Nevada, USA. Presentations included in this volume address the following topics: Geologic Remote Sensing and aerial surveying as applied toward mineral exploration, monitoring of geothermal resources, petroleum exploration, the environmental effects of mining, environment and hydrology, detection of geohazards, and the GIS system and data integration. Some information regarding the use of color imagery in remote sensing is also included.

1996-08-01

115

MTS 94: Challenges and opportunities in the marine environment  

Energy Technology Data Exchange (ETDEWEB)

The Marine Technology Society 1994 conference was held in Washington, D.C., September 7-9, 1994. Titled Challenges and Opportunities in the Marine Environment, the conference offered a wide variety of presentations. State-of-the-art technology, government policies and regulations, and environmental concerns were addressed. Offshore mining, coastal zone management, marine engineering, oceanographic research, educational issues, and global climate change were also well represented in the presentations. The conference proceedings are organized around the daily sessions and roughly 70% of the papers are included.

1994-01-01

116

2005 clean coal and power conference. Conference proceedings  

Energy Technology Data Exchange (ETDEWEB)

The theme of the conference was 'The paradox: today's coal technologies versus tomorrow's promise'. The sessions covered: today's technologies, tomorrow's potential; economic stability; energy security; transition to sustainable energy future; new coal power technologies leading to zero emission coal; existing power plants - improved performance through use of new technology; and carbon capture and storage R & D - challenges and opportunities. Some of the papers only consist of the viewgraphs/overheads.

2005-07-01

117

[SIAM conference on optimization  

Energy Technology Data Exchange (ETDEWEB)

Abstracts are presented of 63 papers on the following topics: large-scale optimization, interior-point methods, algorithms for optimization, problems in control, network optimization methods, and parallel algorithms for optimization problems.

1992-05-10

118

Tests of the ONERA Calibration Models in Three Transonic ...  

Science.gov (United States)

... changes in the wing shock/ separation patterns throughout ... to Reynolds number and tunnel flow quality before ... AGARD Conference Proceedings No ...

1976-11-01

119

Summary Report of the Summer Conference DARPA ...  

Science.gov (United States)

... DARPA-MATERIALS RESEARCH COUNCIL La Jolla, California 0DTIC ... I I 3 Figure 5. Schematic representation of DARPA's Initiative in Concurrent ...

1989-08-04

120

Society of Wetland Scientists/Australian Marine Sciences Association Conference 2006Catchments to Coast  

Science.gov (United States)

... a fully equipped kitchen with microwave and electric cooktop, ensuite bathroom with bath and shower, laundry with ... ...

121

Simulation, modelling and decision in energy systems  

Science.gov (United States)

Separate abstracts are prepared for 74 papers presented at the conference. M.B. Carver, Program Chairman, presented an overview of the meeting. (MCW)

1978-01-01

122

ROSAT Status 130: Update on Wurzburg Conference - HEASARC - NASA  

Science.gov (United States)

Aug 21, 1995... F.D. Two Southern Supernova Remnants Shibazaki, N. Effect of a Superfluid- Crust Coupling on the Neutron Star Evolution Siddiqui, ...

123

Pipe Freeze Prevention for Passive Solar Water Heaters Using a Room-Air Natural Convection Loop: Preprint  

Energy Technology Data Exchange (ETDEWEB)

Conference paper regarding research in the use of freeze prevention for passive solar domestic water heating systems.

2006-05-01

124

Photo Tours: Gulf of Mexico Integrated Science  

Science.gov (United States)

Inventory Project home page Reports, Posters, Presentations Internet Tools - Digital Libraries, IMS's Maps, Aerial Photographs Meetings & Conferences Photo Tours - all...

2011-10-08

125

On the spectroscopy of quantum dots in microcavities  

Energy Technology Data Exchange (ETDEWEB)

At the occasion of the OECS conference in Madrid, we give a succinct account of some recent predictions in the spectroscopy of a quantum dot in a microcavity that remain to be observed experimentally, sometimes within the reach of the current state of the art.

2010-02-01

126

MINExpo international '92  

Energy Technology Data Exchange (ETDEWEB)

Papers from 3 separate conferences are given. The international coal conference covered: advances in control technologies; advances in remote sensing and monitoring; financing and marketing for the future; global climate; health and safety technology; and improving coal's image. Papers from the international minerals and metals conference covered; environmental challenges; financial trends; industry forecast; management strategies; technology advancement; and trade in a changing world. The U.S. issues conference discussed: access to public lands - can you mine if you can't look; innovative technologies in coal mining; innovative technologies in minerals and metals; managing human resource issues; management - controlling costs into the 21st century; and mine waste and water issues.

1992-01-01

127

Knowledge Dissemination and use in Science and mathematics education- A Literature Review  

Science.gov (United States)

... and (3) the exchange of information; materials or perspectives. In 1977, a conference of ... their peers), to products (e.g., curriculum materials, guidebooks, or videos). We will also take ...

128

Jet Noise Modeling for Suppressed and Unsuppressed Aircraft in - NASA  

Science.gov (United States)

Mechanisms, AGARD Conference Proceedings No. 131, 1974, Paper No. 11. ... Olsen, W. and Karchmer, A., Lip Noise Generated by Flow Separation From Nozzle ...

129

Implementation and Evaluation ... - Intelligent Systems Division - NASA  

Science.gov (United States)

[9] Rysdyk, R. T., and Calise, A. J., Fault Tolerant Flight control via Adaptive Neural Augmentation, AIAA. Guidance, Navigation, and Control Conference, Aug. ...

130

Gordon Research Conference on Nonlinear Optics and ...  

Science.gov (United States)

Frm Apwd Dcn,-fl r%,'I-UMENTATION PAGE OMI Mo 04ve On isestVIaVO= to aere hourer p ponse ncudhngthe time for reviewing instrutions. ...

1992-02-05

131

Gordon Research Conference on High Temperature ...  

Science.gov (United States)

... (Argonne Nat. Lab., Speaker: M. Rand (AERE Harwell, UK) ... 19 - Discussion Leader: P. Potter (AERE Harwell, UK) Speaker: YA Chang (Univ. ...

1984-12-03

132

Ellison on Grid computing it's invincible, inevitable  

CERN Multimedia

Speaking to thousands of attendees at Oracle's customer and partner conference, Chairman and CEO Larry Ellison launched Oracle's Grid Computing initiative (1/2 page).

2003-01-01

133

Eighth Goddard Conference on Mass Storage Systems and Technologies ...  

Science.gov (United States)

f4 f5 f1 f2. (a) Overall process decompress ...... involved the shortest learning curve, was available on several platforms, and was ...

134

Directory of Scientists: Gulf of Mexico Estuaries Integrated...  

Science.gov (United States)

Inventory Project home page Reports, Posters, Presentations Internet Tools - Digital Libraries, IMS's Maps, Aerial Photographs Meetings & Conferences Photo Tours - all...

2011-10-08

135

Conference on Information Technology (2nd)/Special Session ...  

Science.gov (United States)

... Topics includes: Formal methods in information engineering, Electronic documents and digital libraries Autonomous robots in embeded systems ...

2004-08-23

136

Conference Proceedings: 7th Annual Review of Progress in ...  

Science.gov (United States)

... 2 Page 27. I PROGRESS: DEVELOPMENT OF AN INTERACTIVE (;RAPHliCS PROGRAM FOR -"M CODES I. Pcng. 1. Choi. ...

1991-03-01

137

Beta-21S: A High Temperature Metastable Beta Titanium Alloy ...  

Science.gov (United States)

... Accession Number : ADD144314. Title : Beta-21S: A High Temperature Metastable Beta Titanium Alloy. Descriptive Note : Conference Proceedings, ...

138

Abstracts of 5. International conference 'Nuclear and Radiation Physics'  

International Nuclear Information System (INIS)

The 5-th International conference 'Nuclear and Radiation Physics' was held in Almaty (Kazakhstan) 26-29 September 2005. Besides basic problems of nuclear and solid state physics the conference paid considerable attention to applied topics important for industry and science in Kazakhstan; they include fuel and construction materials for nuclear power production, new technologies and materials for their production, materials for hydrogen power production, handling and utilization of radioactive waste, analytical methods for combating with illicit trafficking of nuclear and radioactive materials, technologies for reduction and assessment of environmental risk from radiation-hazardous materials and sites, production and application of isotopes, application of nuclear technologies in medicine and industry. On the conference more than 300 papers were presented by participants from 20 countries.

2005-09-26

139

A Method for Integrating Thrust-Vectoring and Actuated Forebody ...  

Science.gov (United States)

flow separation and vortices shed from the airplane forebody when flying at ...... AGARD Conference Proceedings 548: Technologies for Highly Maneuverable ...

140

A Computer Vision System for Inspection of Light Emitting ...  

Science.gov (United States)

... Accession Number : ADD801284. Title : A Computer Vision System for Inspection of Light Emitting Diodes. Descriptive Note : Conference paper,. ...

1986-06-01

141

2009 Conference on Field and Service Robotics, FSR '09  

Science.gov (United States)

... Our primary work to date in this area has been with the Automated Transport and Retrieval System (ATRS) [1]. ATRS enables independent mobility ...

2011-05-15

142

Engineering Relative Compression of Genomes  

CERN Document Server

Technology progress in DNA sequencing boosts the genomic database growth at faster and faster rate. Compression, accompanied with random access capabilities, is the key to maintain those huge amounts of data. In this paper we present an LZ77-style compression scheme for relative compression of multiple genomes of the same species. While the solution bears similarity to known algorithms, it offers significantly higher compression ratios at compression speed over a order of magnitude greater. One of the new successful ideas is augmenting the reference sequence with phrases from the other sequences, making more LZ-matches available.

2011-01-01

143

Welcome to the Department of Estates - University of Bath  

Wastenet

...The system recognises the name and confirms it before it starts to dial. To stop the number being dialled say 'cancel'. If ...of the conference : Press the Recall 'R' button and listen for holding dial tone. Select extension or outside number of the person to ...who is going to join the conference Press Recall 'R' to receive dial tone and select '*' and '4'. The call is ...line is faulty and should be reported to the switchboard operators by dialling '0' and giving full details of the fault, the extension ...

144

The 6th GRS conference  

International Nuclear Information System (INIS)

On the 3. and 4. November 1982 the sixth conference of the Corporation for Reactor Safety (GRS) was held in Cologne's Guerzenich. The theme of this year's meeting was the 'Status of Risk Investigations at Nuclear Power Plants'. A principal topic was a report on findings made by the GRS during the 'Risk Oriented Analysis SNR-300'. The second topic comprised the newest developments within Phase B of the Risk Study of Water Pressure Reactors, the discussion of the dose/effect relationship and considerations on threshold risk values. (orig.).

145

Summary and closing remarks  

Energy Technology Data Exchange (ETDEWEB)

A summary of the topics covered in papers presented at the 1995 Brookhaven joint conference on production, neutralization, and application of negative ion beams is given. The conference topics covered included plasma ion sources, plasma seeding of these sources for increased ion production, beam extraction and transport, computer simulation and design studies, and operation of existing and experimental ion source facilities. Application of the sources to accelerator, tokamak, and thin film deposition are discussed. (AIP) {copyright} {ital 1996 American Institute of Physics.}

1996-07-01

146

Proceedings of the twelfth international conference, applied geologic remote sensing. Practical solutions for real-world problems  

Energy Technology Data Exchange (ETDEWEB)

The topics covered at the conference include: mineral exploration; geological mapping/stratigraphy; environmental monitoring and hydrology; petroleum exploration; radar digital elevation mapping; new commercial remote sensing initiatives; geological hazards and engineering; processing and integration techniques; and hyperspectral geology.

1997-12-31

147

Proceedings of the 1st ACM international conference on digital libraries  

Energy Technology Data Exchange (ETDEWEB)

This document contains papers which were presented at the First ACM International Conference on Digital Libraries. Topics processed for this document included information retrieval and index structures for structured documents. Individual papers have been processed separately for the United States Department of Energy databases.

1996-12-31

148

Proceedings of the 1988 IEEE international conference on robotics and automation. Volume 1  

International Nuclear Information System (INIS)

These proceedings compile the papers presented at the international conference (1988) sponsored by IEEE Council on ''Robotics and Automation''. The subjects discussed were: automation and robots of nuclear power stations; algorithms of multiprocessors; parallel processing and computer architecture; and U.S. DOE research programs on nuclear power plants.

1988-04-24

149

Oceans 82 conference record: Industry, government, education. partners in progress  

Energy Technology Data Exchange (ETDEWEB)

Separate abstracts were prepared for 20 papers in this conference report and includes all papers in the ''engineering'' section (program E). Ocean thermal energy conversion (OTEC), moorings, cables, corrosion protection, corrosion testing, coatings, offshore platforms, pipelines, OTEC models and pilot plants, and energy transfer are topics discussed.

1982-01-01

150

International conference on advances in destructive and non-destructive analysis for environmental monitoring and nuclear forensics. Book of extended synopses  

International Nuclear Information System (INIS)

This document contains 59 extended synopses of the presentations delivered at the conference during oral and poster sessions. The four oral sessions were devoted to: The role of nuclear forensics in combating illicit trafficking and nuclear terrorism; Current capabilities and past experiences; Analytical techniques; and Challenges and alternative approaches. Each of the synopses was indexed separately

2002-10-21

151

InConference : oil and gas sector  

International Nuclear Information System (INIS)

This Insight conference was held to review many of the legal aspects, legislation and regulations dealing with abandoned wells within the petroleum and natural gas industry. Remedial actions to rehabilitate the abandoned sites, legal issues in abandonment, obligations of the owner, the industry-sponsored Orphans Wells Program, were some of the topics discussed.

1997-04-21

152

Fundamental aspects of gas-liquid flows  

Energy Technology Data Exchange (ETDEWEB)

This book presents the papers given at a conference on two-phase flow. Topics considered at the conference included the thermal hydraulics of a feedwater pipe breakage, pressure losses, measurement of void fraction in a rod bundle, laminar filmwise condensation, natural circulation, flow models, bubble dynamics, cavitation, water hammer, and heat transfer augmentation.

1985-01-01

153

Fundamental aspects of gas-liquid flows  

International Nuclear Information System (INIS)

This book presents the papers given at a conference on two-phase flow. Topics considered at the conference included the thermal hydraulics of a feedwater pipe breakage, pressure losses, measurement of void fraction in a rod bundle, laminar filmwise condensation, natural circulation, flow models, bubble dynamics, cavitation, water hammer, and heat transfer augmentation.

1985-11-17

154

Conference on climate and water. Volume 2  

Energy Technology Data Exchange (ETDEWEB)

This book contains the Proceedings of the Conference on Climate and Water under the following groupings: Impacts of climatic variability and change-resulting from the changes in hydrological variables; Aquatic environment; Terrestrial environment; Coastal zones and navigation; Urban and industrial water supply and drainage; Energy production; Intropogenic changes of climate and water management problems; Flood potential; Irrigation and land drainage.

1989-12-31

155

Conference on climate and water  

Energy Technology Data Exchange (ETDEWEB)

This book contains the Proceedings of the Conference on Climate and Water under the following groupings: Impacts of climatic variability and change-resulting from the changes in hydrological variables; Aquatic environment; Terrestrial environment; Coastal zones and navigation; Urban and industrial water supply and drainage; Energy production; Intropogenic changes of climate and water management problems; Flood potential; Irrigation and land drainage.

1989-01-01

156

Asilomar conference on managing complexity in high energy physics: A summary and renaming of the conference  

Energy Technology Data Exchange (ETDEWEB)

The complex aspects of high energy physics work are briefly described, and approaches to managing them are discussed. Management of software and data are covered. For managing complexity in experimental physics, the choice of building or buying processor systems is addressed and the issues of compatibility and standardization are discussed. (LEW)

1987-02-01

157

Ultraconserved Elements: Analyses of Dosage Sensitivity, Motifs and Boundaries  

UK PubMed Central (United Kingdom)

Ultraconserved elements (UCEs) are sequences that are identical between reference genomes of distantly related species. As they are under negative selection and enriched near or in specific classes...Full Text Available

2008-12-01

158

The Importance of Mitochondrial DNA in Aging and Cancer  

UK PubMed Central (United Kingdom)

Mitochondrial dysfunction has been implicated in premature aging, age-related diseases, and tumor initiation and progression. Alterations of the mitochondrial genome accumulate both in aging tissue...Full Text Available

159

The COG database: an updated version includes eukaryotes  

UK PubMed Central (United Kingdom)

BackgroundThe availability of multiple, essentially complete genome sequences of prokaryotes and eukaryotes spurred both the demand and the opportunity for the construction of an...Full Text Available

160

Systems medicine: the future of medical genomics and healthcare  

UK PubMed Central (United Kingdom)

High-throughput technologies for DNA sequencing and for analyses of transcriptomes, proteomes and metabolomes have provided the foundations for deciphering the structure, variation and function of the...Full Text Available

161

Proteinortho: Detection of (Co-)orthologs in large-scale analysis  

UK PubMed Central (United Kingdom)

BackgroundOrthology analysis is an important part of data analysis in many areas of bioinformatics such as comparative genomics and molecular phylogenetics. The ever-increasing flood...Full Text Available

162

Polymer Genomics: An Insight into Pharmacology and Toxicology of Nanomedicines 1  

UK PubMed Central (United Kingdom)

Synthetic polymers and nanomaterials display selective phenotypic effects in cells and in the body that affect signal transduction mechanisms involved in inflammation, differentiation, proliferation,...Full Text Available

2006-12-30

163

Plasticity in patterns of histone modifications and chromosomal proteins in Drosophila heterochromatin  

UK PubMed Central (United Kingdom)

Eukaryotic genomes are packaged in two basic forms, euchromatin and heterochromatin. We have examined the composition and organization of Drosophila melanogaster heterochromatin in...Full Text Available

2011-02-01

164

Open-source software accelerates bioinformatics  

UK PubMed Central (United Kingdom)

A report on the Wellcome Trust/Cold Spring Harbor Genome Informatics meeting, Cold Spring Harbor, USA, 7-11 May 2003.

2003-01-01

165

Nucleomorph Ribosomal DNA and Telomere Dynamics in Chlorarachniophyte Algae  

British Library Electronic Table of Contents (United Kingdom)

ABSTRACT. Chlorarachniophytes are enigmatic marine unicellular algae that acquired photosynthesis by secondary endosymbiosis. Chlorarachniophytes are unusual in that the nucleus of the engulfed algal cell (a green alga) persists in a miniaturized form, termed a nucleomorph. The nucleomorph genome of the model chlorarachniophyte, Bigelowiella natans CCMP621, is 373 kilobase pairs (kbp) in size, the smallest nuclear genome characterized to date. The B. natans nucleomorph genome is composed of three chromosomes, each with canonical eukaryotic telomeres and sub telomeric ribosomal DNA (rDNA) operons transcribed away from the chromosome end. Here we present the complete rDNA operon and telomeric region from the nucleomorph genome of Lotharella oceanica CCMP622, a newly characterized chlorarachn...

2010-01-01

166

Manipulating the Xenopus genome with transposable elements  

UK PubMed Central (United Kingdom)

The study of amphibian embryogenesis has provided important insight into the mechanisms of vertebrate development. The frog Xenopus laevis has been an important model of vertebrate...Full Text Available

2007-01-01

167

Identification of pork derivatives in food products by species-specific polymerase chain reaction (PCR) for halal verification  

British Library Electronic Table of Contents (United Kingdom)

Pork identification in four types of food products, which are sausages and the casings, bread and biscuits, using species-specific polymerase chain reaction (PCR) detection of a conserved region in the mitochondrial (mt) 12S ribosomal RNA (rRNA) gene was developed. Genomic DNA of the food products were successfully extracted except for the casing samples, where no genomic DNA was detected. The extracted genomic DNA was then subjected to PCR amplification targeting the specific regions of the 12S rRNA gene. The genomic DNA from the food products were found to be of good quality and produced clear PCR products on the amplification of 12S rRNA gene of 387 base pairs (bp) from pork species. The species-specific PCR identification yielded excellent results for identification of pork derivatives...

2007-01-01

168

Human endogenous retroviruses: transposable elements with potential ?  

UK PubMed Central (United Kingdom)

Human endogenous retroviruses (HERVs) are a significant component of a wider family of retroelements that constitute part of the human genome. These viruses, perhaps representative of previous exogenous...Full Text Available

2004-10-01

169

Human cDNA mapping using fluorescence in situ hybridization. Final progress report, April 1, 1994--July 31, 1997  

Energy Technology Data Exchange (ETDEWEB)

The ultimate goal of this research is to generate and apply novel technologies to speed completion and integration of the human genome map and sequence with biomedical problems. To do this, techniques were developed and genome-wide resources generated. This includes a genome-wide Mapped and Integrated BAC/PAC Resource that has been used for gene finding, map completion and anchoring, breakpoint definition and sequencing. In the last period of the grant, the Human Mapped BAC/PAC Resource was also applied to determine regions of human variation and to develop a novel paradigm of primate evolution through to humans. Further, in order to more rapidly evaluate animal models of human disease, a BAC Map of the mouse was generated in collaboration with the MTI Genome Center, Dr. Bruce Birren.

1997-12-31

170

Genome analysis with inter-nucleotide distances  

UK PubMed Central (United Kingdom)

Motivation: DNA sequences can be represented by sequences of four symbols, but it is often useful to convert the symbols into real or complex numbers for further analysis. Several mapping...Full Text Available

2009-12-01

171

Extracellular Signaling through the Microenvironment: A Hypothesis Relating Carcinogenesis, Bystander Effects, and ...  

Science.gov (United States)

... Extracellular Signaling through the Microenvironment: A Hypothesis Relating Carcinogenesis, Bystander Effects, and Genomic InstabilityMary Helen Barcellos-Hoff1a ... ...

172

Evaluating Phylogenetic Congruence in the Post-Genomic Era  

UK PubMed Central (United Kingdom)

Congruence is a broadly applied notion in evolutionary biology used to justify multigene phylogeny or phylogenomics, as well as in studies of coevolution, lateral gene transfer, and as evidence for...Full Text Available

2011-01-01

173

Developmentally programmed endoreduplication in animals  

UK PubMed Central (United Kingdom)

Development of a fertilized egg into an adult human requires trillions of cell divisions, the vast majority of which duplicate their genome once and only once. Nevertheless, trophoblast giant...Full Text Available

2009-05-15

174

Computational biology for ageing  

UK PubMed Central (United Kingdom)

High-throughput genomic and proteomic technologies have generated a wealth of publicly available data on ageing. Easy access to these data, and their computational analysis, is of great importance in...Full Text Available

2011-01-12

175

Comparing Genomes within the Species Mycobacterium tuberculosis  

UK PubMed Central (United Kingdom)

The study of genetic variability within natural populations of pathogens may provide insight into their evolution and pathogenesis. We used a Mycobacterium tuberculosis high-density...Full Text Available

2001-04-01

176

Comparative genomics of insect juvenile hormone biosynthesis?  

UK PubMed Central (United Kingdom)

The biosynthesis of insect juvenile hormone (JH) and its neuroendocrine control are attractive targets for chemical control of insect pests and vectors of disease. To facilitate the molecular...Full Text Available

2006-04-01

177

Ancestral Genomes, Sex, and the Population Structure of Trypanosoma cruzi  

UK PubMed Central (United Kingdom)

Acquisition of detailed knowledge of the structure and evolution of Trypanosoma cruzi populations is essential for control of Chagas disease....Full Text Available

2006-03-01

178

A framework for evolutionary systems biology  

UK PubMed Central (United Kingdom)

BackgroundMany difficult problems in evolutionary genomics are related to mutations that have weak effects on fitness, as the consequences of mutations with large effects are often...Full Text Available

179

Targeted Capture and Next-Generation Sequencing Identifies C9orf75, Encoding Taperin, as the Mutated Gene in Nonsyndromic Deafness DFNB79  

UK PubMed Central (United Kingdom)

Targeted genome capture combined with next-generation sequencing was used to analyze 2.9 Mb of the DFNB79 interval on chromosome 9q34.3, which includes 108 candidate genes. Genomic...Full Text Available

2010-03-12

180

Genome-wide association studies of gastric adenocarcinoma and esophageal squamous cell carcinoma identify a shared susceptibility locus in PLCE1 at 10q23  

UK PubMed Central (United Kingdom)

We conducted a genome-wide association study of gastric cancer (GC) and esophageal squamous cell carcinoma (ESCC) in ethnic Chinese subjects in which we genotyped 551,152 single nucleotide polymorphisms...Full Text Available

2010-09-01

181

Draft Genome Sequence of Shewanella sp. Strain HN-41, Which Produces Arsenic-Sulfide Nanotubes.  

Science.gov (United States)

The dissimilatory metal reducing bacterium Shewanella sp. strain HN-41 was first reported to produce novel photoactive As-S nanotubes via reduction of As(V) and S(2)O(3)(2-) under anaerobic conditions. Here we report the draft genome sequence and annotation of strain HN-41. PMID:21868804

2011-09-01

182

A unique horizontal gene transfer event has provided the octocoral mitochondrial genome with an active mismatch repair gene that has potential for an unusual self-contained function  

UK PubMed Central (United Kingdom)

BackgroundThe mitochondrial genome of the Octocorallia has several characteristics atypical for metazoans, including a novel gene suggested to function in DNA repair. This mtMutS...Full Text Available

183

A genome-wide association study of cleft lip with and without cleft palate identifies risk variants near MAFB and ABCA4  

UK PubMed Central (United Kingdom)

Case-parent trios were used in a genome wide association study of cleft lip with/without cleft palate (CL/P). SNPs near two genes not previously associated with CL/P [MAFB:...Full Text Available

2010-06-01

184

Construction of the Savannah River Ecology Laboratory Conference Center  

International Nuclear Information System (INIS)

This Environmental Assessment (EA) reviews the environmental consequences associated with the proposed action of granting a site use permit to construct and operate a conference center on an approximately 70-acre tract of land on the Savannah River Site (SRS). While the proposed action requires an administrative decision by DOE, this EA reviews the linked action of physically constructing and operating a conference center. The SRS is a DOE-owned nuclear production facility encompassing approximately 200,000 acres in southwestern South Carolina. The proposed conference center would have an area of approximately 4,000 square feet, and would infrequently accommodate as many as 150 people, with the average being about 20 people per day. In addition to the No-Action alternative, under which the Research Foundation would not require the 70-acre tract of SRS land for a conference center, this EA considers site ...

2006-05-15

185

Complete genome sequence of Actinosynnema mirum type strain (101T)  

Energy Technology Data Exchange (ETDEWEB)

Actinosynnema mirum Hasegawa et al. 1978 is the type species of the genus, and is of phylogenetic interest because of its central phylogenetic location in the Actino-synnemataceae, a rapidly growing family within the actinobacterial suborder Pseudo-nocardineae. A. mirum is characterized by its motile spores borne on synnemata and as a producer of nocardicin antibiotics. It is capable of growing aerobically and under a moderate CO2 atmosphere. The strain is a Gram-positive, aerial and substrate mycelium producing bacterium, originally isolated from a grass blade collected from the Raritan River, New Jersey. Here we describe the features of this organism, together with the complete genome sequence and annotation. This is the first complete genome sequence of a member of the family Actinosynnemataceae, and only the second sequence from the actinobacterial suborder Pseudonocardineae. The 8,248,144 bp long single replicon genome ...

2009-05-20

186

Bisulfite genomic sequencing of DNA from dried blood spot microvolume samples.  

Science.gov (United States)

DNA methylation is an important event in epigenetic changes in cells, and a fundamental regulator of gene transcription. Bisulfite genomic sequencing is a powerful technique used in studies of DNA methylation. However, the established procedures often require relatively large amounts of DNA. In everyday practice, samples submitted for analysis might contain very small amounts of poor quality material, as is often the case with forensic stain samples. In this study, we assess a modified, more efficient method of bisulfite genomic sequencing. Genomic DNA extracted from 3-mm dried blood spots using QIAamp micro kit was treated with sodium bisulfite (using EpiTect kit). Subsequent methylation-specific PCR (MSP) followed by DNA sequencing displayed the differentially methylated region of imprinted gene SNRPN. Our results show that this new combination of efficient DNA extraction and bisulfite treatment provides high quality ...

2011-07-01

187

The conference proceedings from Clean Air `94 - first North American conference & exhibition, emerging clean air technologies and business opportunities  

Energy Technology Data Exchange (ETDEWEB)

The conference was organized to bring together scientific and business people from Canada, United States, and Mexico to foster the protection and improvement of the environment and to promote sustainable development in the three NAFTA countries. The sessions are international cooperation and partnerships (panel discussion), markets, market access, economic instruments, venture and capital growth, economic instruments versus regulations, international financial institutions, partnerships and networks, government support programs (panel), acid rain, stratospheric ozone, smog and ground level ozone, innovative measurement methods, hazardous air pollutants, respirable fine particulates, climate change prevention technologies, pollution prevention technologies, indoor air technology, and posters. Selected papers have been abstracted separately.

1994-09-01

188

Sandia`s network for supercomputing `95: Validating the progress of Asynchronous Transfer Mode (ATM) switching  

Energy Technology Data Exchange (ETDEWEB)

The Advanced Networking Integration Department at Sandia National Laboratories has used the annual Supercomputing conference sponsored by the IEEE and ACM for the past three years as a forum to demonstrate and focus communication and networking developments. For Supercomputing `95, Sandia elected: to demonstrate the functionality and capability of an AT&T Globeview 20Gbps Asynchronous Transfer Mode (ATM) switch, which represents the core of Sandia`s corporate network, to build and utilize a three node 622 megabit per second Paragon network, and to extend the DOD`s ACTS ATM Internet from Sandia, New Mexico to the conference`s show floor in San Diego, California, for video demonstrations. This paper documents those accomplishments, discusses the details of their implementation, and describes how these demonstrations supports Sandia`s overall strategies in ATM networking.

1996-04-01

189

Proceedings of the PHEV 2007 conference : where the grid meets the road  

International Nuclear Information System (INIS)

This conference examined the potential role of plug-in hybrid electric vehicles (PHEVs) which are gaining interest around the world. Emerging PHEV technologies were reviewed along with the role that biofuels and electricity play in their widespread use. It was attended by members of industry, academia, utilities, government and institutions to review on-going research and demonstrations of PHEV projects across North America. The purpose was to understand how PHEV technologies can be integrated into current and future transportation systems and the electrical power grid. Other objectives were to establish a primarily-Canadian network focused on PHEV-related issues to promote public engagement for the plug-in highway. The possible role of government support for PHEV research, development and commercialization was also discussed. In addition to workshops and poster sessions, this conference featured 75 presentations, of which 37 have been ...

2007-11-01

190

Proceedings of the 8. CANMET/ACI international conference on superplasticizers and other chemical admixtures in concrete[ACI SP-239  

Energy Technology Data Exchange (ETDEWEB)

This international conference brought together representatives from industry, academia and government agencies to present the latest developments on the subject of chemical admixtures and superplasticizers in concrete. Recent technological advances in the development of superplasticizers were reviewed, as well as new approaches to manufactured aggregates. The influence of new materials on the rheology of cement systems was discussed, as well as the influence of superplasticizers on various types of aggregates. The addition of hydrophobic admixtures in corrosion prevention strategies were reviewed. Various interactions between cements and superplasticizers were evaluated. Issues concerning adsorption and concrete materials were also investigated. A total of 70 papers were presented at the conference, of which 3 have been catalogued separately for inclusion in this database. refs., tabs., figs.

2006-07-01

191

Preface: phys. stat. sol. (c) 7/11 12  

British Library Electronic Table of Contents (United Kingdom)

AbstractTrends in Nanotechnology (TNT2009) This special issue of Physica Status Solidi presents representative contributions describing the main topics covered at the 10th Trends in Nanotechnology (TNT2009) International Conference, held in Barcelona (Spain), September 07 11, 2009. During the last years many international or national conferences have emerged in response to the growing awareness of the importance of nanotechnology as key issue for the future scientific and technological development. Among these, the conference series Trends in Nanotechnology has become one of the most important meeting points in the nano technology field: it provides fresh organisation ideas, brings together well known speakers, and promotes a suitable environment for discussions, exchanging ideas, enhancin...

2010-01-01

192

Netrawalm: Network Based Resource Aware Application Layer Multicast for Multiparty Video Conference  

CERN Document Server

IP Multicast is one of the most absolute method for large bandwidth Internet applications such as video conference, IPTV, E-Learning and Telemedicine etc., But due to security and management reason IP Multicast is not enabled in Internet backbone routers. To achieve these challenges, lot of Application Layer Multicast (ALM) has been proposed. All the existing protocols such as NICE, ZIGZAG and OMNI are trying to reduce average delay by forming a Multicast tree. But still that problem has not been addressed fully. We are proposing a new protocol called NetRawALM, which will address the average delay, Reliability between nodes, Scalability of conference, Heterogeneity and resilient data distribution for real time multimedia applications by constructing the Network based Resource aware Multicast tree algorithm. This is very dynamic and decentralised. The proposed architecture is a LAN aware; it is used to reduce Internet Traffic.

2011-01-01

193

National action to mitigate global climate change  

Energy Technology Data Exchange (ETDEWEB)

Over 170 participants from 60 countries met for three days in Copenhagen from 7 to 9 June 1994 to discuss howe the aims of the United Nations Framework convention on Climate Change can be translated into practical action. The Conference was organised by the UNEP collaborating Centre on Energy and Environment (UCCEE), with financial support from the Danish International Development Agency (Danida), the Global Environment Facility (GEF), the United Nations Environment Programme (UNEP) and Risoe National Laboratory, Denmark. The main objective of the conference was to identify common approaches to national mitigation analysis for countries to use in meeting their commitments under the FCCC, and in setting priorities for national actions. Although addressing a broader theme, the conference marked the completion and publication of the second phase on UNEP Greenhouse Gas Abatement Costing Study. (au)

1995-06-01

194

Hydro '88: incorporating third international conference on small hydro conference papers  

Energy Technology Data Exchange (ETDEWEB)

Thirty-nine conference papers review practical and topical aspects of hydroelectric development, from planning and design to construction, operation and refurbishment. More than half of the papers deal with small-scale hydro, reflecting the continuing strong interest in this subject throughout the world. The planning and economic evaluation of large-scale hydro schemes and pumped-storage plants, and environmental aspects of hydroelectric developments are also discussed. A special session has also been included on hydro in Latin America, where some of the world's largest schemes are planned or under construction. The papers reproduced here draw on the expertise of engineers from eighteen countries in North and South America, Europe, Asia, Australasia and Africa. All the papers were selected and indexed separately.

1988-01-01

195

12th Symposium on Space Nuclear Power and Propulsion. Conference on Alternative Power from Space (APFS),Conference on Accelerator-Driven Transmutation Technologies and Applications (A-DTTA)  

International Nuclear Information System (INIS)

These proceedings represent papers presented at the 12th symposium on Space Nuclear Power and Propulsion held in Albuquerque, New Mexico. The symposium theme was ''commercialization and technology transfer''. The topics discussed include: wireless power transmission, solar power from space next generation spacecraft, space power electronics and power management, flight testing of components, manufacturing and processing of materials, nuclear propulsion, reactors and shielding and many others of interest to the scientific community representing industry, government and academic institutions. There were 163 papers presented at the conference and 60 have been abstracted for the Energy Science and Technology database.

1995-01-08

196

'11-th International Conference - School on Plasma Physics and Controlled Fusion and 2-nd International Workshop on the Role of Electric Fields in Plasma Confinement in Stellarators and Tokamaks'. Book of abstracts  

International Nuclear Information System (INIS)

About 210 abstracts by Ukrainian and foreign authors submitted to the 11-th International Conference on Plasma Physics and Controlled Fusion and 2-nd Alushta International Workshop on the Role of Electric Fields in Plasma Confinement in Stellarators and Tokamaks have been considered by Conference Program Committee members. All the abstracts have been divided into 9 groups: Magnetic confinement systems (stellarators, tokamaks, alternative conceptions); plasma heating and current drive; ITER and fusion reactor aspects; basic plasma physics; space plasma; plasma dynamics and plasma-wall interaction; plasma electronics; low temperature plasma and plasma technologies; plasma diagnostics.

2006-09-11

197

Wolsung-1 nuclear power plant. Update report, 1983 June.  

Science.gov (United States)

The Wolsung-1 CANDU 600 MWe plant is now in operation. This paper provides an update on the design, construction and commissioning progress reported at last year's conference. The accomplishments of the past year are highlighted with emphasis on how the s...

1983-01-01

198

UTK-EERC ~ Staff - Jack N. Barkenbus  

Wastenet

... Tschantz, Performance Evaluation of Constructed Urban Stormwater Detention Ponds in the Knoxville Area, proceedings and presentation to International Conference on Decision Making in Urban and Civil Engineering, Lyon, France, November 22, 2000. B.A. Tschanz, Current Problems, Practices, and ...

199

Thin Film Solar Cells and Solar Cell Testing, Volume II Proceedings of the Fourth Photovoltaic Specialists Conference  

Science.gov (United States)

Thin film solar cells and solar cell testing - photovoltaic cells, radiation damage to cadmium sulfide solar cells, and airplane testing of solar cells

1964-01-01

200

The Harris M. Schurmeier Collection, 1970-1986 3.0 cubic ... - NASA  

Science.gov (United States)

SDI was a space-based defense system designed to ... satellites that could detect a massive nuclear launch within seconds, orbiting laser weapons to destroy the ..... AIAA Washington Conference, memorandum from T. W. Hamilton to H. ...

201

The Case for Selection at CCR5-?32  

UK PubMed Central (United Kingdom)

The C-C chemokine receptor 5, 32 base-pair deletion (CCR5-Δ32) allele confers strong resistance to infection by the AIDS virus HIV. Previous studies have suggested...Full Text Available

2005-11-01

203

Student Understanding of the First and Second Laws of Thermodynamics  

Science.gov (United States)

This presentation from the 2006 PTEC Conference presents education research on topics in thermodynamics. Student responses to conceptual thermodynamics questions, and the conceptions they reveal, are presented. Tutorial materials developed to help students gain a better understanding of the topic are also presented.

2006-09-30

204

SUBMIT TO: AM105 CONFERENCE TITLE: Earth Observing Systems VI - NASA  

Science.gov (United States)

BAE SYSTEMS Infrared Imaging Systems. MS 209. 2 Forbes Road. Lexington, MA 02421 -7306. (781) 863-3762. (781) 863-4809 (fax) ken.overoye @lmco.com ...

205

Recent US Patterns and Predictors of Prevalent Diabetes among Acute Myocardial Infarction Patients  

UK PubMed Central (United Kingdom)

Background. Diabetes mellitus (DM) confers high vascular risk and is a growing national epidemic. We assessed clinical characteristics and prevalence of diagnosed DM among patients...Full Text Available

206

Rapid detection of epidermal growth factor receptor mutations with multiplex PCR and primer extension in lung cancer  

UK PubMed Central (United Kingdom)

Epidermal growth factor receptor (EGFR) kinase domain mutations hyperactivate the kinase and confer kinase addiction of the non-small-cell lung cancer (NSCLC) tumor...Full Text Available

207

ROCK DEFORMATION. Final Progress Report  

Energy Technology Data Exchange (ETDEWEB)

The Gordon Research Conference (GRC) on ROCK DEFORMATION was held at II Ciocco from 5/19/02 thru 5/24/02. Emphasis was placed on current unpublished research and discussion of the future target areas in this field.

2002-05-24

208

RECOD 87  

International Nuclear Information System (INIS)

This fourth volume of the RECOD 87 proceedings contains two parts: 1 - Authors' communications which arrived after the conference. 2 - Authors' corrections concerning communications which were already published in the three first volumes.

209

Proceedings of the CERI 2006 natural gas conference : North American markets : fragile, handle with care  

International Nuclear Information System (INIS)

This conference was attended by decision makers throughout the supply chain in the natural gas industry who face the continuing challenges of changes in market mechanisms, pricing options, and transmission alternatives. It provided an opportunity to review issues affecting producers, shippers, marketers, and end-users in an environment of tight energy markets and high, inelastic demand. The constraints on adequate energy supplies are influenced by economic factors, current and future resources, materials, equipment, skilled labour, technology and financial capital. The 8 sessions of the conference dealt with the tight North American gas supply; the slow development of new supplies; resource access issues, including politics and supply security; the geopolitics of natural gas; impacts of high prices on the North American economy; energy industry impacts of high natural gas prices; domestic politics and high natural gas prices; and, radical ...

2006-03-13

210

Proceedings of the 58. annual technical meeting of the Petroleum Society of CIM : CIPC 2007 : Because technology changes everything  

International Nuclear Information System (INIS)

This conference and trade show provided a forum to present new, emerging and existing technologies that will play a key role in ensuring that hydrocarbon exploitation occurs in a sustainable manner, where costs and resource recovery are optimized while minimizing environmental impacts. The challenge of developing maturing basins, frontier lands and unconventional resources was discussed. In particular, the application of thermal recovery methods such as steam assisted gravity drainage (SAGD) for the in-situ recovery of heavy oils and bitumens was reviewed and compared with the performance of alternative enhanced energy recovery technologies such as vapor extraction (VAPEX). The conference was attended by local and international participants in the petroleum sector, including managers, engineers, technologists, geologists, and other petroleum industry specialists. The conference featured 132 presentations addressing topics ...

2007-06-12

211

Proceedings of the 1996 oil heat technology conference and workshop  

Energy Technology Data Exchange (ETDEWEB)

This Conference is a key technology transfer activity supported by the ongoing Combustion Equipment Technology (Oil-Heat R and D) program at BNL, and is aimed at providing a forum for the exchange of information among international researchers, engineers, manufacturers, and marketers of oil-fired space-conditioning equipment. The objectives of the Conference were to: identify and evaluate the state-of-the-art and recommend new initiatives for higher efficiency, a cleaner environment, and to satisfy consumer needs cost-effectively, reliably, and safely; and foster cooperation among federal and industrial representatives with the common goal of sustained national economic growth and energy security via energy conservation. The 1996 Oil Technology Conference comprised: (a) fourteen technical papers, and (b) four workshops which focused on mainstream issues in oil-heating technology, namely: oilheat research agenda forum; fan ...

1996-07-01

212

Prediction method abstracts  

Energy Technology Data Exchange (ETDEWEB)

This conference was held December 4--8, 1994 in Asilomar, California. The purpose of this meeting was to provide a forum for exchange of state-of-the-art information concerning the prediction of protein structure. Attention if focused on the following: comparative modeling; sequence to fold assignment; and ab initio folding.

1994-12-31

213

Planetary Defense ... - Asteroid Comet Impact Hazards - NASA  

Science.gov (United States)

Mar 1, 2004 ... For a summary of papers from a 4-day AIAA conference held February ... m is less than $400 million, with both ground-based and space-based options possible. .... from concerns about a new generation of nuclear weapons. ...

214

Pathway to Licensure for Protective Antigen-based Anthrax Vaccines ...  

Science.gov (United States)

... Weiss, S., D. Kobiler, H. Levy, H. Marcus, A. Pass, N. Rothschild, and Z ... of Bacillus anthracis spores conferred by a protective antigen-based vaccine in rabbits ...

215

Organizing and managing for energy efficiency  

Energy Technology Data Exchange (ETDEWEB)

Details of the functioning of some of industry's most successful energy programs are examined. A Conference Board survey was mailed to 921 corporations, yielding 292 usable responses. More detailed information was gathered from discussions and interviews. (MHR)

1983-01-01

216

Northward Market Extension for Passive Solar Water Heaters by Using Pipe Freeze Protection with Freeze-Tolerant Piping: Preprint  

Energy Technology Data Exchange (ETDEWEB)

Conference paper regarding research in freeze-protection methods that could extend market acceptance for passive solar domestic water heating systems in more northern climates if the U.S.

2006-05-01

217

NREL preprints for the 23rd IEEE Photovoltaic Specialists Conference  

Energy Technology Data Exchange (ETDEWEB)

Topics covered include various aspects of solar cell fabrication and performance. Aluminium-gallium arsenides, cadmium telluride, amorphous silicon, and copper-indium-gallium selenides are all characterized in their applicability in solar cells.

1993-05-01

218

Molecular and Kinetic Comparison of the Novel Extended-Spectrum ?-Lactamases CTX-M-25 and CTX-M-26  

UK PubMed Central (United Kingdom)

CTX-M-25 is a novel extended-spectrum β-lactamase isolated from a single Canadian Escherichia coli isolate. Susceptibility testing demonstrated that this enzyme confers resistance...Full Text Available

2004-12-01

219

Mach 4 Performance of Hypersonic Inlet with Rectangular-to ...  

Science.gov (United States)

station in flowmeter used for mass flow calculation. Introduction. THE design .... length (as a result of a less conservative boundary-layer separation criterion), 2) slight ..... ical Flow, AGARD Conference Proceedings, No. 30, 1968. 5Kantrowitz ...

220

MSFC ESO Applied ... - Global Hydrology and Climate Center - NASA  

Science.gov (United States)

In the IEEE Marine Technology Society OCEANS 2009 Conference, Biloxi. October 26-29, 2009. Biloxi, MS. Al-Hamdan, M.; Estes, M.; Quattrochi, D.; Thom, R.; ...

221

Loss of Nocturnin, a circadian deadenylase, confers resistance to hepatic steatosis and diet-induced obesity  

UK PubMed Central (United Kingdom)

The mammalian circadian system consists of a central oscillator in the suprachiasmatic nucleus of the hypothalamus, which coordinates peripheral clocks in organs throughout the body. Although circadian...Full Text Available

2007-06-05

222

Leptin Resistance Protects Mice from Hyperoxia-induced Acute Lung Injury  

UK PubMed Central (United Kingdom)

Rationale: Human data suggest that the incidence of acute lung injury is reduced in patients with type II diabetes mellitus. However, the mechanisms by which diabetes confers protection...Full Text Available

2007-03-15

223

Identification and Disruption of Two Discrete Loci Encoding Hyaluronic Acid Capsule Biosynthesis Genes hasA, hasB, and hasC in Streptococcus uberis  

UK PubMed Central (United Kingdom)

The hyaluronic acid capsule of Streptococcus uberis has been implicated in conferring resistance to phagocytosis by bovine neutrophils. Construction of a bank of random insertion mutants...Full Text Available

2001-01-01

224

Gaseous fuels and other alternative fuels  

Energy Technology Data Exchange (ETDEWEB)

This book contains papers relating to the 1990 Future Transportation Technology Conference and Exposition. Included are the following papers; Examination of rich mixtures operation of a dual fuel engine, A hybrid natural gas vehicles, Performance analysis of a spark ignited engine with ETBE as a blending agent.

1990-01-01

225

Expression of the ?B-Dependent General Stress Regulon Confers Multiple Stress Resistance in Bacillus subtilis  

UK PubMed Central (United Kingdom)

The alternative sigma factor ςB of Bacillus subtilis is required for the induction of approximately 100 genes after the imposition of a whole range of stresses and...Full Text Available

1999-07-01

226

Energy and economy - global interdependencies. Proceedings. Vol. 9. Implications of environmental issues  

Energy Technology Data Exchange (ETDEWEB)

The 7 conference papers in Vol. 9 review the implications of environmental problems and discuss the consequences of pollution abatement measures, especially for the economics of energy conversion. The future developments of pollutant emissions are assessed.

1985-01-01

227

Emerging diseases in Chiroptera: why bats?  

UK PubMed Central (United Kingdom)

A conference entitled ‘2nd International Berlin Bat Meeting: Bat Biology and Infectious Diseases’ was held between the 19 and 21 of February 2010 in Berlin, Germany. Researchers from...Full Text Available

2010-08-23

228

Differential targeting of Tetrahymena ORC to ribosomal DNA and non-rDNA replication origins  

UK PubMed Central (United Kingdom)

The Tetrahymena thermophila origin recognition complex (ORC) contains an integral RNA subunit, 26T RNA, which confers specificity to the amplified ribosomal DNA (rDNA) origin by base...Full Text Available

2009-02-04

229

Decontamination of nuclear facilities  

International Nuclear Information System (INIS)

Thirty-seven papers were presented at this conference in five sessions. Topics covered include regulation, control and consequences of decontamination; decontamination of components and facilities; chemical and non-chemical methods of decontamination; and TMI decontamination experience.

1982-09-19

230

Cloning of the mouse hepatitis virus (MHV) receptor: expression in human and hamster cell lines confers susceptibility to MHV.  

UK PubMed Central (United Kingdom)

The cellular receptor for murine coronavirus mouse hepatitis virus (MHV)-A59 is a member of the carcinoembryonic antigen (CEA) family of glycoproteins in the immunoglobulin superfamily. We isolated...Full Text Available

1991-12-01

231

Catalyst preparation and characterization, session 1  

Energy Technology Data Exchange (ETDEWEB)

The abstracts of all the presentations (1 plenary session, 2 keynotes, 52 oral communications, 496 posters) of the thematic session 1: 'catalyst preparation and characterization' are gathered in the CD-Rom of the conference. The main application described concerns the petroleum industry. (O.M.)

2004-07-01

232

ASME proceedings of the 31. national heat transfer conference: Volume 2. HTD-Volume 324  

Energy Technology Data Exchange (ETDEWEB)

This volume is divided into the following sections: (1) fundamentals of convection heat transfer; (2) fundamentals of heat transfer with impinging jets; and (3) fundamentals of heat transfer augmentation. Separate abstracts were prepared for most papers in this volume.

1996-12-31

233

ABO blood group and the risk of placental malaria in sub-Saharan Africa  

UK PubMed Central (United Kingdom)

BackgroundIn malarious areas of the world, a higher proportion of the population has blood group O than in non-malarious areas. This is probably due to a survival advantage conferred...Full Text Available

234

A Pragmatic Approach to Implementing Best Practices for Clinical Decision Support Systems in Computerized Provider Order Entry Systems  

UK PubMed Central (United Kingdom)

Incorporation of clinical decision support (CDS) capabilities is required to realize the greatest benefits from computerized provider order entry (CPOE) systems. Discussions at a conference on CDS in...Full Text Available

2007-01-01

235

A Nonlinear Dynamic Inversion L Adaptive Controller for - NASA  

Science.gov (United States)

Adaptive Neural Augmentation , AIAA Guidance, Navigation, and. Control Conference, Aug. 1998. [2] J. T. Kaneshige, J. Bull, and J. J. Totah, Generic Neural ...

236

A New Spin on Research Translation: The Boston Consensus Conference on Human Biomonitoring  

UK PubMed Central (United Kingdom)

BackgroundTranslating research to make it more understandable and effective (research translation) has been declared a priority in environmental health but does not always include...Full Text Available

2009-04-01

237

Trans-generational radiation-induced chromosomal instability in the female enhances the action of chemical mutagens  

Energy Technology Data Exchange (ETDEWEB)

Genomic instability can be produced by ionising radiation, so-called radiation-induced genomic instability, and chemical mutagens. Radiation-induced genomic instability occurs in both germinal and somatic cells and also in the offspring of irradiated individuals, and it is characterised by genetic changes including chromosomal rearrangements. The majority of studies of trans-generational, radiation-induced genomic instability have been described in the male germ line, whereas the authors who have chosen the female as a model are scarce. The aim of this work is to find out the radiation-induced effects in the foetal offspring of X-ray-treated female rats and, at the same time, the possible impact of this radiation-induced genomic instability on the action of a chemical mutagen. In order to achieve both goals, the quantity and quality of chromosomal damage were analysed. In order to ...

2008-04-02

238

Exploiting rice-sorghum synteny for targeted development of EST-SSRs to enrich the sorghum genetic linkage map.  

Science.gov (United States)

The sequencing and detailed comparative functional analysis of genomes of a number of select botanical models open new doors into comparative genomics among the angiosperms, with potential benefits for improvement of many orphan crops that feed large populations. In this study, a set of simple sequence repeat (SSR) markers was developed by mining the expressed sequence tag (EST) database of sorghum. Among the SSR-containing sequences, only those sharing considerable homology with rice genomic sequences across the lengths of the 12 rice chromosomes were selected. Thus, 600 SSR-containing sorghum EST sequences (50 homologous sequences on each of the 12 rice chromosomes) were selected, with the intention of providing coverage for corresponding homologous regions of the sorghum genome. Primer pairs were designed and polymorphism detection ability was assessed using parental pairs of two existing sorghum ...

2009-08-08

239

Reports of the second All-Union conference on the chemistry of transplutonium elements (Dmitrovgrad, June 21-23, 1963)  

Energy Technology Data Exchange (ETDEWEB)

The nine papers presented at this conference cover the following topics: the systematization, condensed description, and prediction of sets of anion exchange extraction constants on the basis of their statistical computer treatment; characteristics and uses of solid extractants containing D2EHPA and TBP for separating the transplutonium elements; enrichment of americium 242m and americium 242 by the Szilard-Chalmers method; an x-ray diffraction pattern analysis for transplutonium compounds; the radiation chemistry of americium; and the effects of alpha irradiation on the behavior of americium in perchlorate solutions.

1987-05-01

240

Proceedings of the third international conference on containment design and operation. v.1  

International Nuclear Information System (INIS)

The second international conference on containment design and operation included sessions on the following topics: performance and regulatory requirements; radionuclide behaviour; severe accident design and analysis; operation, maintenance, leaking and aging of containment systems; thermal hydraulic behaviour of containment systems; hydrogen mixing and mitigation; design methods and concepts; code validation; structural analysis and response tests; passive safety systems; aerosol behaviour; containment reliability, integrity, and risk assessment; hydrogen deflagration and detonation. Due prominence was given to CANDU and other PHWR reactors. The individual papers have been abstracted separately.

1994-10-19

241

Proceedings of the third annual better reclamation with trees conference  

Energy Technology Data Exchange (ETDEWEB)

The twenty-three papers presented at this conference discussed requirements of land reclamation under the Federal surface mining regulations, evaluation techniques for assessing reclaimed land, spoil bank chemistry and its change with time, establishment techniques (vegetative propagation, containerized seedlings, nurse vegetation, nitrogen-fixing tree species, direct seeding, and general cultivation techniques), and results from early land reclamation trials. Twenty-two papers have been abstracted separately. 291 references, 16 figures, 80 tables.

1983-01-01

242

Proceedings of the fourth international airborne remote sensing conference and exhibition/ 21st Canadian symposium on remote sensing  

Energy Technology Data Exchange (ETDEWEB)

The theme of the conference was recent developments in airborne remote sensing and their applications. The proceedings contain the papers presented at 14 general sessions and 13 interactive sessions covering airborne platforms, sensor systems, airborne/spaceborne synergy, atmospheric and oceanic measurements, land cover/land use, emergency response and reconnaissance, data handling, forestry, agriculture, water resources, geospatial reference, system calibration, environmental monitoring and planning, and information product advancements. Two papers are abstracted separately.

1999-07-01

243

Proceedings of the 8. CANMET/ACI international conference on superplasticizers and other chemical admixtures in concrete : supplementary papers[ACI SP-239  

Energy Technology Data Exchange (ETDEWEB)

This book provided a set of supplementary papers provided to delegates at the eighth international CANMET/ACI conference on superplasticizers and chemical admixtures in concrete. Recent research on chemical admixtures and superplasticizers was presented along with new approaches to the practical application of concrete admixtures. The presentations highlighted technological advances in the development of superplasticizers and new approaches to the manufacture and implementation of aggregates. Issues regarding the application of plasticizers with various aggregates were addressed, and interactions between cements and superplasticizers were evaluated. Four of the supplementary papers have been catalogued separately for inclusion in this database. refs., tabs., figs.

2006-07-01

244

Plasmid-conferred tetracycline resistance confers collateral cadmium sensitivity to E. coli cells  

Energy Technology Data Exchange (ETDEWEB)

E. coli HB101 cells transformed to tetracycline resistance with the plasmids pMB9 or pBR322 display a 10/sup 5/-10/sup 6/-fold lower plating efficiency on agar containing 440 ..mu..M CdCl/sub 2/ than nontransformed cells. When DNA is inserted into the BamH1 site of the plasmid tet gene, or when DNA spanning the BamH1 site is deleted, tetracycline resistance and cadmium hypersensitivity are both lost. In contrast, insertion of DNA into the ampicillin resistance gene does not affect cadmium hypersensitivity.

1982-01-01

245

Inter-ministerial mission against the greenhouse effect; Mission interministerielle contre l'effet de serre  

Energy Technology Data Exchange (ETDEWEB)

In the framework of the negotiations on the climatic changes, beginning at Rio in 1992, the France received an UN conference from the 4 to 15 of september 2000. This conference determined the necessary actions for the Kyoto protocol validation. This document presents in two part the program of these days. The first part is devoted to the world government policy and the second part defines the french actions decided to fight against the climatic change. A glossary of the main terms adapted to the climatic change domain, is also provided. (A.L.B.)

2000-07-01

246

Insight conference reports : proceedings of the smart meters forum  

Energy Technology Data Exchange (ETDEWEB)

This forum provided insights into Ontario's new smart meter program. Challenges related to implementing the smart meter program were reviewed, and various functional and operational considerations of the meters were considered. The implications and benefits of using real time metering systems were discussed along with issues related to energy conservation and demand management. Various communications technologies were considered in relation to smart metering program implementation. Issues related to pricing and pricing policies were also discussed. The conference featured 11 presentations, of which 2 have been catalogued separately for inclusion in this database. refs., tabs., figs.

2006-07-01

247

Environmental scarcity: The international dimension  

Energy Technology Data Exchange (ETDEWEB)

National environmental policies have international repercussions: Thus the question arises as to how environmental policy should be designed in order to cope with international environmental problems in an efficient way. These topics were discussed in a conference held at the Kiel Institute of World Economics on July 5-6, 1990. The conference papers and comments are presented in this volume. Environmental scarcity has important international aspects. First, national environmental endowment and policy influence competitiveness and trade. Second, transfrontier pollution is a specific issue. Third, global environmental problems require a solution. This classification of the international aspects of the environmental issue provides the outline of the book. (orig./HSCH).

1991-01-01

248

DKV conference report 2000 - 27th year. Working section 4. Vol. 4; DKV-Tagungsbericht 2000 - 27. Jahrgang. Arbeitsabteilung 4. Bd. 4  

Energy Technology Data Exchange (ETDEWEB)

Vol. 4 of the DKV Conference Proceedings 2000 contains 19 papers on air quality, thermal comfort, space HVAC engineering and alternative cooling concepts. [German] Der Band 4 des DKV-Tagungsberichts 2000 enthaelt 19 Beitraege. Sie befassen sich mit speziellen Themen der Heiztechnik; Luftqualitaet und Behaglichkeit; Raumlufttechnik und Alternativen Kuehlkonzepten.

2001-07-01

249

SEPT9_i1 and genomic instability: Mechanistic insights and relevance to tumorigenesis  

British Library Electronic Table of Contents (United Kingdom)

Abstract Septins are highly conserved cytoskeletal GTP-binding proteins implicated in numerous cellular processes from apoptosis to vesicle trafficking. Septins have been associated with leukemia and solid tumor malignancies, including breast, ovarian, and prostate. We previously reported that high SEPT9_i1 expression in human mammary epithelial cell lines (HMECs) led to malignant cellular phenotypes such as increased cell proliferation, invasiveness, motility, and genomic instability. Our goal here was to better understand how SEPT9_i1 expression might contribute to genomic instability and malignant progression. First, we confirmed that even transient expression of SEPT9_i1 was sufficient to increase aneuploidy in HMECs. We then analyzed SEPT9_i1 by immunoprecipitation and immunofluoresce...

2011-01-01

250

Federal technology transfer and the human genome project. Background paper  

Energy Technology Data Exchange (ETDEWEB)

As with other areas of biomedical research, the expectation is that the results of genome research will yield commercially valuable products of benefits to human health. The report, analyzes universities`, companies`, and researchers` experiences and perspectives since enactment of federal laws to enhance technology transfer--especially as it pertains to research funded by the National Institutes of Health and the Department of Energy, the agencies funding U.S. efforts in the Human Genome Project. OTA prepared this background paper with the assistance of a panel of advisors and reviewers selected for their expertise and diverse points of view. Additionally, hundreds of individuals cooperated with OTA staff through interviews or by providing written material. These authorities were drawn from government, academia, industry, and professional societies worldwide.

1995-09-01

251

A genomic library-based amplification approach (GL-PCR) for the mapping of multiple IS6110 insertion sites and strain differentiation of Mycobacterium tuberculosis  

British Library Electronic Table of Contents (United Kingdom)

Evidence suggests that insertion of the IS6110 element is not without consequence to the biology of Mycobacterium tuberculosis complex strains. Thus, mapping of multiple IS6110 insertion sites in the genome of biomedically relevant clinical isolates would result in a better understanding of the role of this mobile element, particularly with regard to transmission, adaptability and virulence. In the present paper, we describe a versatile strategy, referred to as GL-PCR, that amplifies IS6110-flanking sequences based on the construction of a genomic library. M. tuberculosis chromosomal DNA is fully digested with HincII and then ligated into a plasmid vector between T7 and T3 promoter sequences. The ligation reaction product is transformed into Escherichia coli and selective PCR amplification...

2006-01-01

252

solQTL: a tool for QTL analysis, visualization and linking to genomes at SGN database  

UK PubMed Central (United Kingdom)

BackgroundA common approach to understanding the genetic basis of complex traits is through identification of associated quantitative trait loci (QTL). Fine mapping QTLs requires...Full Text Available

253

piggyBac is a flexible and highly active transposon as compared to Sleeping Beauty, Tol2, and Mos1 in mammalian cells  

UK PubMed Central (United Kingdom)

A nonviral vector for highly efficient site-specific integration would be desirable for many applications in transgenesis, including gene therapy. In this study we directly compared the genomic integration...Full Text Available

2006-10-10

254

chipD: a web tool to design oligonucleotide probes for high-density tiling arrays  

UK PubMed Central (United Kingdom)

chipD is a web server that facilitates design of DNA oligonucleotide probes for high-density tiling arrays, which can be used in a number of genomic applications such as ChIP-chip or gene-expression...Full Text Available

2010-07-01

255

Visual Genome-Wide RNAi Screening to Identify Human Host Factors Required for Trypanosoma cruzi Infection  

UK PubMed Central (United Kingdom)

The protozoan parasite Trypanosoma cruzi is the etiologic agent of Chagas disease, a neglected tropical infection that affects millions of people in the Americas. Current chemotherapy...Full Text Available

256

Viruses with More Than 1,000 Genes: Mamavirus, a New Acanthamoeba polyphaga mimivirus Strain, and Reannotation of Mimivirus Genes  

UK PubMed Central (United Kingdom)

The genome sequence of the Mamavirus, a new Acanthamoeba polyphaga mimivirus strain, is reported. With 1,191,693 nt in length and 1,023 predicted protein-coding genes, the Mamavirus...Full Text Available

2011-01-01

257

Ubiquitin over-expression phenotypes and ubiquitin gene molecular misreading during aging in Drosophila melanogaster  

UK PubMed Central (United Kingdom)

Molecular Misreading (MM) is the inaccurate conversion of genomic information into aberrant proteins. For example, when RNA polymerase II transcribes a GAGAG motif it synthesizes at low frequency RNA...Full Text Available

258

Two separate domains within vesicular stomatitis virus phosphoprotein support transcription when added in trans.  

UK PubMed Central (United Kingdom)

The structural phosphoprotein NS of vesicular stomatitis virus, in association with the virion-associated RNA polymerase L protein, transcribes the genome ribonucleoprotein template in vitro. It contains...Full Text Available

1987-12-01

259

Tumour suppressor ING1b maintains genomic stability upon replication stress  

UK PubMed Central (United Kingdom)

The lesion bypass pathway, which is regulated by monoubiquitination of proliferating cell nuclear antigen (PCNA), is essential for resolving replication stalling due to DNA lesions. This process is...Full Text Available

2011-05-01

260

Tumor-Endothelial Interaction Links the CD44+/CD24- Phenotype with Poor Prognosis in Early-Stage Breast Cancer1  

UK PubMed Central (United Kingdom)

Materials and MethodsThe genomic effects of tumor-endothelial interactions in cancer are not yet well characterized. To study this interaction in breast...Full Text Available

2009-10-01

261

Transposons as tools for enhancer trap screens in vertebrates  

UK PubMed Central (United Kingdom)

DNA transposons are efficient tools in transgenesis and have therefore become popular in the analysis of the regulatory genome in vertebrates via enhancer trap screens. Here, I discuss recent progress...Full Text Available

2007-01-01

262

Transposon-based screens for cancer gene discovery in mouse models  

UK PubMed Central (United Kingdom)

Significant emphasis has recently been placed on the characterization of the human cancer genome. This effort has been assisted by the development of new DNA sequencing technologies that allow...Full Text Available

2010-08-01

263

Transposable elements in fish functional genomics: technical challenges and perspectives  

UK PubMed Central (United Kingdom)

The recent introduction of several transposable elements in zebrafish opens new frontiers for genetic manipulation in this important vertebrate model. This review discusses transposable elements as...Full Text Available

2007-01-01

264

Transposable elements are enriched within or in close proximity to xenobiotic-metabolizing cytochrome P450 genes  

UK PubMed Central (United Kingdom)

BackgroundTransposons, i.e. transposable elements (TEs), are the major internal spontaneous mutation agents for the variability of eukaryotic genomes. To address the general issue...Full Text Available

265

Transcriptional Organization of the Avian Adenovirus CELO  

UK PubMed Central (United Kingdom)

A detailed map of the transcriptional organization of the CELO virus genome was produced. Recent computer analysis of CELO virus has indicated the presence of 38 putative open reading frames (ORFs)....Full Text Available

1998-11-01

266

Tissue Effect on Genetic Control of Transcript Isoform Variation  

UK PubMed Central (United Kingdom)

Current genome-wide association studies (GWAS) are moving towards the use of large cohorts of primary cell lines to study a disease of interest and to assign biological relevance to the genetic signals...Full Text Available

2009-08-01

267

The struggle for life of the genome's selfish architects  

UK PubMed Central (United Kingdom)

Transposable elements (TEs) were first discovered more than 50 years ago, but were totally ignored for a long time. Over the last few decades they have gradually attracted increasing interest from research...Full Text Available

268

The polymorphism architecture of mouse genetic resources elucidated using genome-wide resequencing data: implications for QTL discovery and systems genetics  

UK PubMed Central (United Kingdom)

Mouse genetic resources include inbred strains, recombinant inbred lines, chromosome substitution strains, heterogeneous stocks, and the Collaborative Cross (CC). These resources were generated through...Full Text Available

2007-07-01

269

The missing graphical user interface for genomics  

UK PubMed Central (United Kingdom)

AbstractThe Galaxy package empowers regular users to perform rich DNA sequence analysis through a much-needed and user-friendly graphical web interface.See research article...Full Text Available

2010-01-01

270

The complete mitochondrial genome of Atelura formicaria (Hexapoda: Zygentoma) and the phylogenetic relationships of basal insects.  

Science.gov (United States)

In this study, the complete sequence of the mitochondrial DNA (mtDNA) of Atelura formicaria (Hexapoda: Zygentoma) is described. The molecule is 15.205 bp in length and it is the third complete mt genome sequenced from the Zygentoma. The genome organization conforms with the putative ancestral insect gene arrangement. All protein coding genes use standard initiation codons (methionine and isoleucine). The exception is nad4 that starts with GTG, a codon used for this purpose in other insect species. A peculiar strand skew bias is observed, given that the PCGs encoded on the J-strand contain more thymines than adenines and more cytosines than guanines. This trend in nucleotide composition has been observed also in the "firebrat" Thermobia domestica (Zygentoma, Lepismatidae), but differs from that of the majority of hexapod species, including Tricholepidion gertschi (Zygentoma, Lepidotrichidae), where adenines and cytosines outnumber thymines and ...

2009-03-11

271

The chromosomal association/dissociation of the chromatin insulator protein Cp190 of Drosophila melanogaster is mediated by the BTB/POZ domain and two acidic regions  

UK PubMed Central (United Kingdom)

BackgroundChromatin insulators or boundary elements are a class of functional elements in the eukaryotic genome. They regulate gene transcription by interfering with promoter-enhancer...Full Text Available

272

The Pseudomonas aeruginosa PA01 Gene Collection  

UK PubMed Central (United Kingdom)

Pseudomonas aeruginosa, a common inhabitant of soil and water, is an opportunistic pathogen of growing clinical relevance. Its genome, one of the largest among bacteria [5570 open reading...Full Text Available

2004-10-01

273

The Human Ageing Genomic Resources: online databases and tools for biogerontologists  

UK PubMed Central (United Kingdom)

SummaryAgeing is a complex, challenging phenomenon that will require multiple, interdisciplinary approaches to unravel its puzzles. To assist basic research on ageing, we developed...Full Text Available

2009-02-01

274

The Exceptionally Large Genome of Hendra Virus: Support for Creation of a New Genus within the Family Paramyxoviridae  

UK PubMed Central (United Kingdom)

An outbreak of acute respiratory disease in Hendra, a suburb of Brisbane, Australia, in September 1994 resulted in the deaths of 14 racing horses and a horse trainer. The causative agent was a new member...Full Text Available

2000-11-01

275

The Anopheles gambiae glutathione transferase supergene family: annotation, phylogeny and expression profiles  

UK PubMed Central (United Kingdom)

BackgroundTwenty-eight genes putatively encoding cytosolic glutathione transferases have been identified in the Anopheles gambiae genome. We manually annotated these...Full Text Available

276

Ternary Complex Formation on the Adenovirus Packaging Sequence by the IVa2 and L4 22-Kilodalton Proteins?  

UK PubMed Central (United Kingdom)

Assembly of infectious adenovirus particles requires seven functionally redundant elements at the left end of the genome, termed A repeats, that direct packaging of the DNA. Previous studies revealed...Full Text Available

2007-11-01

277

Studying bacterial transcriptomes using RNA-seq  

UK PubMed Central (United Kingdom)

Genome-wide studies of bacterial gene expression are shifting from microarray technology to second generation sequencing platforms. RNA-seq has a number of advantages over hybridization-based techniques,...Full Text Available

2010-10-01

278

Structural analysis of a hepatitis B virus genome integrated into chromosome 17p of a human hepatocellular carcinoma.  

UK PubMed Central (United Kingdom)

Hepatitis B virus (HBV) is clearly a factor in the development of hepatocellular carcinoma, but its mechanism of action remains obscure. One possibility is that the HBV integration event alters the...Full Text Available

1988-11-01

279

Structural Basis for Acetylated Histone H4 Recognition by the Human BRD2 Bromodomain*  

UK PubMed Central (United Kingdom)

Recognition of acetylated chromatin by the bromodomains and extra-terminal domain (BET) family proteins is a hallmark for transcriptional activation and anchoring viral genomes to mitotic chromosomes...Full Text Available

2010-03-05

280

Statistical properties of nucleotide clusters in DNA sequences*  

UK PubMed Central (United Kingdom)

Using the complete genome of Plasmodium falciparum 3D7 which has 14 chromosomes as an example, we have examined the distribution functions for the amount of C or G and A or T consecutively...Full Text Available

2005-05-01

281

Short RNA half-lives in the slow-growing marine cyanobacterium Prochlorococcus  

UK PubMed Central (United Kingdom)

BackgroundRNA turnover plays an important role in the gene regulation of microorganisms and influences their speed of acclimation to environmental changes. We investigated whole-genome...Full Text Available

2010-01-01

282

Severe teratozoospermia and its influence on pronuclear morphology, embryonic cleavage and compaction  

UK PubMed Central (United Kingdom)

BackgroundFertilization, cell division and embryo development depend on genomic contributions from male and female gametes. We hypothesize that teratozoospermic sperm influences...Full Text Available

283

Restriction endonuclease analysis of porcine Pasteurella multocida isolates from Quebec.  

UK PubMed Central (United Kingdom)

We have used restriction endonuclease analysis (REA) of genomic DNA to classify porcine Pasteurella multocida isolates with similar capsular and somatic serotypes, and to monitor the distribution of...Full Text Available

1990-10-01

284

Resolving Individuals Contributing Trace Amounts of DNA to Highly Complex Mixtures Using High-Density SNP Genotyping Microarrays  

UK PubMed Central (United Kingdom)

We use high-density single nucleotide polymorphism (SNP) genotyping microarrays to demonstrate the ability to accurately and robustly determine whether individuals are in a complex genomic DNA mixture....Full Text Available

2008-08-01

285

ReplicationDomain: a visualization tool and comparative database for genome-wide replication timing data  

UK PubMed Central (United Kingdom)

BackgroundEukaryotic DNA replication is regulated at the level of large chromosomal domains (0.5–5 megabases in mammals) within which replicons are activated relatively synchronously....Full Text Available

286

Remobilization of Tol2 transposons in Xenopus tropicalis  

UK PubMed Central (United Kingdom)

BackgroundThe Class II DNA transposons are mobile genetic elements that move DNA sequence from one position in the genome to another. We have previously demonstrated that the naturally...Full Text Available

287

Reduced-Median-Network Analysis of Complete Mitochondrial DNA Coding-Region Sequences for the Major African, Asian, and European Haplogroups  

UK PubMed Central (United Kingdom)

The evolution of the human mitochondrial genome is characterized by the emergence of ethnically distinct lineages or haplogroups. Nine European, seven Asian (including Native American), and three African...Full Text Available

2002-05-01

288

Reconstruction of the complete human cytomegalovirus genome in a BAC reveals RL13 to be a potent inhibitor of replication  

UK PubMed Central (United Kingdom)

Human cytomegalovirus (HCMV) in clinical material cannot replicate efficiently in vitro until it has adapted by mutation. Consequently, wild-type HCMV differ fundamentally from the passaged strains...Full Text Available

2010-09-01

289

Polymorphic Regions Affecting Human Height Also Control Stature in Cattle  

UK PubMed Central (United Kingdom)

Orthologous positions of 55 genes associated with height in four human populations were located on the bovine genome. Single nucleotide polymorphisms close to eight of these genes were significantly...Full Text Available

2011-03-01

290

Palindromic Sequence Plays a Critical Role in Human Foamy Virus Dimerization  

UK PubMed Central (United Kingdom)

The retroviral RNA genome is dimeric, consisting of two identical strands of RNA linked near their 5′ ends by a dimer linkage structure. Previously it was shown that human foamy virus (HFV)...Full Text Available

2001-04-01

291

Onset of Quiescence Following p53 Mediated Down-Regulation of H2AX in Normal Cells  

UK PubMed Central (United Kingdom)

Normal cells, both in vivo and in vitro, become quiescent after serial cell proliferation. During this process, cells can develop immortality with genomic instability,...Full Text Available

292

New common variants affecting susceptibility to basal cell carcinoma  

UK PubMed Central (United Kingdom)

In a follow-up to our previously reported genome-wide association study of cutaneous basal cell carcinoma (BCC)1, we describe here several new susceptibility...Full Text Available

2009-08-01

293

New Pathogenicity Marker Found in the Plasticity Region of the Helicobacter pylori Genome  

UK PubMed Central (United Kingdom)

Comparison of gastric carcinoma and gastritis isolates showed the presence of genes, probably carcinoma associated (JHP947 and JHP940), that are situated in a Helicobacter...Full Text Available

2003-04-01

294

Mutations in TPRN Cause a Progressive Form of Autosomal-Recessive Nonsyndromic Hearing Loss  

UK PubMed Central (United Kingdom)

We performed genome-wide homozygosity mapping in a large consanguineous family from Morocco and mapped the autosomal-recessive nonsyndromic hearing loss (ARNSHL) in this family to the DFNB79...Full Text Available

2010-03-12

295

Mutational Analysis of cis-Acting RNA Signals in Segment 7 of Influenza A Virus?  

UK PubMed Central (United Kingdom)

The genomic viral RNA (vRNA) segments of influenza A virus contain specific packaging signals at their termini that overlap the coding regions. To further characterize cis-acting signals...Full Text Available

2008-12-01

296

Multiplexed, rapid detection of H5N1 using a PCR-free nanoparticle-based genomic microarray assay  

UK PubMed Central (United Kingdom)

BackgroundFor more than a decade there has been increasing interest in the use of nanotechnology and microarray platforms for diagnostic applications. In this report, we describe...Full Text Available

297

Mapping cis-Regulatory Domains in the Human Genome UsingMulti-Species Conservation of Synteny  

Energy Technology Data Exchange (ETDEWEB)

Our inability to associate distant regulatory elements with the genes that they regulate has largely precluded their examination for sequence alterations contributing to human disease. One major obstacle is the large genomic space surrounding targeted genes in which such elements could potentially reside. In order to delineate gene regulatory boundaries we used whole-genome human-mouse-chicken (HMC) and human-mouse-frog (HMF) multiple alignments to compile conserved blocks of synteny (CBS), under the hypothesis that these blocks have been kept intact throughout evolution at least in part by the requirement of regulatory elements to stay linked to the genes that they regulate. A total of 2,116 and 1,942 CBS>200 kb were assembled for HMC and HMF respectively, encompassing 1.53 and 0.86 Gb of human sequence. To support the existence of complex long-range regulatory domains within these CBS we analyzed the prevalence and distribution of ...

2005-06-13

298

Longitudinal assessment of lung cancer progression in the mouse using in vivo micro-CT imaging  

UK PubMed Central (United Kingdom)

Purpose: Small animal micro-CT imaging is being used increasingly in preclinical biomedical research to provide phenotypic descriptions of genomic models. Most of this imaging is coincident...Full Text Available

2010-09-01

299

Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies  

UK PubMed Central (United Kingdom)

Recently, genome-wide association studies (GWAS) have linked the human LIN28B locus to height and timing of menarche [1-Full Text Available

2010-07-01

300

Kinetic Complexity of the Global Response to Glucocorticoid Receptor Action  

UK PubMed Central (United Kingdom)

We have characterized the kinetic response of gene targets throughout the murine genome to transcriptional modulation by the glucocorticoid receptor (GR). In contrast to a model in which multiple genes...Full Text Available

2009-04-01

301

Involvement of the Matrix and Nucleocapsid Domains of the Bovine Leukemia Virus Gag Polyprotein Precursor in Viral RNA Packaging  

UK PubMed Central (United Kingdom)

The RNA packaging process for retroviruses involves a recognition event of the genome-length viral RNA by the viral Gag polyprotein precursor (PrGag), an important step in particle morphogenesis. The...Full Text Available

2003-09-01

302

Interpopulation hybridization results in widespread viability selection across the genome in Tigriopus californicus  

UK PubMed Central (United Kingdom)

BackgroundGenetic interactions within hybrids influence their overall fitness. Understanding the details of these interactions can improve our understanding of speciation. One experimental...Full Text Available

303

Integrase-directed recovery of functional genes from genomic libraries  

UK PubMed Central (United Kingdom)

Large population sizes, rapid growth and 3.8 billion years of evolution firmly establish microorganisms as a major source of the planet's biological and genetic diversity. However, up to 99% of the...Full Text Available

2009-09-01

304

Insights into the Genome of Large Sulfur Bacteria Revealed by Analysis of Single Filaments  

UK PubMed Central (United Kingdom)

Marine sediments are frequently covered by mats of the filamentous Beggiatoa and other large nitrate-storing bacteria that oxidize hydrogen sulfide using either oxygen or nitrate, which...Full Text Available

2007-09-01

305

Inferring transcription factor complexes from ChIP-seq data  

UK PubMed Central (United Kingdom)

Chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq) allows researchers to determine the genome-wide binding locations of individual transcription factors (TFs) at high resolution....Full Text Available

2011-08-01

306

In vitro dimerization of human immunodeficiency virus type 1 (HIV-1) spliced RNAs  

UK PubMed Central (United Kingdom)

The human immunodeficiency virus type 1 (HIV-1) packages its genomic RNA as a dimer of homologous RNA molecules that has to be selected among a multitude of cellular and viral RNAs. Interestingly, spliced...Full Text Available

2007-12-01

307

Impaired replication dynamics at the FRA3B common fragile site  

UK PubMed Central (United Kingdom)

Chromosomal common fragile sites (CFSs) are genetically unstable regions of the genome that are induced by conditions that impair DNA replication. In this report, we show that treatment with the DNA...Full Text Available

2010-01-01

308

Identification of plasmid and Bacillus subtilis chromosomal recombination sites used for pE194 integration.  

UK PubMed Central (United Kingdom)

The plasmid pE194 (3.7 kilobases) is capable of integrating into the genome of the bacterial host Bacillus subtilis in the absence of the major homology-dependent RecE recombination system. Multiple...Full Text Available

1989-05-01

310

Identification of copy number variations and common deletion polymorphisms in cattle  

UK PubMed Central (United Kingdom)

BackgroundRecently, the discovery of copy number variation (CNV) led researchers to think that there are more variations of genomic DNA than initially believed. Moreover, a certain...Full Text Available

311

Identification of a Central DNA Flap in Feline Immunodeficiency Virus  

UK PubMed Central (United Kingdom)

A duplication of the polypurine tract (PPT) at the center of the human immunodeficiency virus type 1 (HIV-1) genome (the cPPT) has been shown to prime a separate plus-strand initiation and to result...Full Text Available

2001-10-01

312

Identification of Genes Affecting the Toxicity of Anti-Cancer Drug Bortezomib by Genome-Wide Screening in S. pombe  

UK PubMed Central (United Kingdom)

Bortezomib/PS-341/Velcade, a proteasome inhibitor, is widely used to treat multiple myeloma. While several mechanisms of the cytotoxicity of the drug were proposed, the actual mechanism remains elusive....Full Text Available

313

Identification and In Vivo Characterization of NvFP-7R, a Developmentally Regulated Red Fluorescent Protein of Nematostella vectensis  

UK PubMed Central (United Kingdom)

BackgroundIn recent years, the sea anemone Nematostella vectensis has emerged as a critical model organism for comparative genomics and developmental biology. Although...Full Text Available

314

Human Immunodeficiency Virus type-1 reverse transcriptase exists as post-translationally modified forms in virions and cells  

UK PubMed Central (United Kingdom)

BackgroundHIV-1 reverse transcriptase (RT) is a heterodimer composed of p66 and p51 subunits and is responsible for reverse transcription of the viral RNA genome into DNA. RT can...Full Text Available

315

Genomic patterns of pathogen evolution revealed by comparison of Burkholderia pseudomallei, the causative agent of melioidosis, to avirulent Burkholderia thailandensis  

UK PubMed Central (United Kingdom)

BackgroundThe Gram-negative bacterium Burkholderia pseudomallei (Bp) is the causative agent of the human disease melioidosis. To understand the evolutionary mechanisms...Full Text Available

316

Genomic but Not Antigenomic Hepatitis Delta Virus RNA Is Preferentially Exported from the Nucleus Immediately after Synthesis and Processing  

UK PubMed Central (United Kingdom)

Hepatitis delta virus (HDV) contains a viroid-like circular RNA that replicates via a double rolling circle replication mechanism. It is generally assumed that HDV RNA is synthesized and remains exclusively...Full Text Available

2002-04-01

317

Genomic blueprint of Hahella chejuensis, a marine microbe producing an algicidal agent  

UK PubMed Central (United Kingdom)

Harmful algal blooms, caused by rapid growth and accumulation of certain microalgae in the ocean, pose considerable impacts on marine environments, aquatic industries and even public health. Here, we...Full Text Available

2005-01-01

318

Genomic Expression Libraries for the Identification of Cross-Reactive Orthopoxvirus Antigens  

UK PubMed Central (United Kingdom)

Increasing numbers of human cowpox virus infections that are being observed and that particularly affect young non-vaccinated persons have renewed interest in this zoonotic disease. Usually causing...Full Text Available

319

Genomic Evidence for the Evolution of Streptococcus equi: Host Restriction, Increased Virulence, and Genetic Exchange with Human Pathogens  

UK PubMed Central (United Kingdom)

The continued evolution of bacterial pathogens has major implications for both human and animal disease, but the exchange of genetic material between host-restricted pathogens is rarely considered....Full Text Available

2009-03-01

320

Genomic Diversity and Evolution of Mycobacterium ulcerans Revealed by Next-Generation Sequencing  

UK PubMed Central (United Kingdom)

Mycobacterium ulcerans is the causative agent of Buruli ulcer, the third most common mycobacterial disease after tuberculosis and leprosy. It is an emerging infectious disease that...Full Text Available

2009-09-01

321

Genomic Content of Bordetella pertussis Clinical Isolates Circulating in Areas of Intensive Children Vaccination  

UK PubMed Central (United Kingdom)

BackgroundThe objective of the study was to analyse the evolution of Bordetella pertussis population and the influence of herd immunity in different areas of the...Full Text Available

322

Genome-wide profiling of forum domains in Drosophila melanogaster  

UK PubMed Central (United Kingdom)

Forum domains are stretches of chromosomal DNA that are excised from eukaryotic chromosomes during their spontaneous non-random fragmentation. Most forum domains are 50–200 kb in length....Full Text Available

2011-05-01

323

Genome-wide linkage scan for contraction velocity characteristics of knee musculature in the Leuven Genes for Muscular Strength Study  

UK PubMed Central (United Kingdom)

The torque-velocity relationship is known to be affected by ageing, decreasing its protective role in the prevention of falls. Interindividual variability in this torque-velocity relationship is partly...Full Text Available

2008-09-01

324

Genome-wide expression profiling reveals distinct clusters of transcriptional regulation during bovine preimplantation development in vivo  

UK PubMed Central (United Kingdom)

Bovine embryos can be generated by in vitro fertilization or somatic nuclear transfer; however, these differ from their in vivo counterparts in many aspects and exhibit a higher proportion of developmental...Full Text Available

2008-12-16

325

Genome-Wide Transcriptome Profiling of Region-Specific Vulnerability to Oxidative Stress in the Hippocampus  

UK PubMed Central (United Kingdom)

Neurons in the hippocampal CA1 region are particularly sensitive to oxidative stress (OS), whereas those in CA3 are resistant. To uncover mechanisms for selective CA1 vulnerability to OS, we...Full Text Available

2007-08-01

326

Genome-Wide Transcriptional Response of Chemostat-Cultured Escherichia coli to Zinc  

UK PubMed Central (United Kingdom)

Zinc is an essential trace metal ion for growth, but an excess of Zn is toxic and microorganisms express diverse resistance mechanisms. To understand global bacterial responses to excess Zn, we conducted...Full Text Available

2005-02-01

327

Genome-Wide Analysis Reveals a Major Role in Cell Fate Maintenance and an Unexpected Role in Endoreduplication for the Drosophila FoxA Gene Fork Head  

UK PubMed Central (United Kingdom)

Transcription factors drive organogenesis, from the initiation of cell fate decisions to the maintenance and implementation of these decisions. The Drosophila embryonic salivary gland...Full Text Available

328

Genome Sequence of Campylobacter jejuni strain 327, a strain isolated from a turkey slaughterhouse  

UK PubMed Central (United Kingdom)

Campylobacter is one of the leading causes of food-borne gastroenteritis and has a high prevalence in poultry. Campylobacter jejuni subsp. jejuni 327 is a subspecies...Full Text Available

329

Genetic screening: The vista of genomic medicine  

UK PubMed Central (United Kingdom)

The accelerating development of biochemical and DNA-based diagnostic tests for human genetic conditions in the last decade has engendered a revolution in genetic diagnosis. Both genetic testing and...Full Text Available

2011-01-01

330

Genetic aspects of birth defects: new understandings of old problems  

UK PubMed Central (United Kingdom)

Over the past two decades, combined advances in genetics, developmental biology and biochemistry have transformed the study of human birth defects. This review describes the importance of genome architecture,...Full Text Available

2007-07-01

331

Generation of microsatellite repeat families by RTE retrotransposons in lepidopteran genomes  

UK PubMed Central (United Kingdom)

BackgroundDeveloping lepidopteran microsatellite DNA markers can be problematical, as markers often exhibit multiple banding patterns and high frequencies of non-amplifying "null"...Full Text Available

332

Generation of a BAC-based physical map of the melon genome  

UK PubMed Central (United Kingdom)

BackgroundCucumis melo (melon) belongs to the Cucurbitaceae family, whose economic importance among horticulture crops is second only to Solanaceae. Melon has high...Full Text Available

333

Gene-gene and gene-environment interactions: new insights into the prevention, detection and management of coronary artery disease  

UK PubMed Central (United Kingdom)

Despite the recent success of genome-wide association studies (GWASs) in identifying loci consistently associated with coronary artery disease (CAD), a large proportion of the genetic components of...Full Text Available

334

Gene expression patterns in four brain areas associate with quantitative measure of estrous behavior in dairy cows  

UK PubMed Central (United Kingdom)

BackgroundThe decline noticed in several fertility traits of dairy cattle over the past few decades is of major concern. Understanding of the genomic factors underlying fertility,...Full Text Available

335

Functional interaction between the Werner Syndrome protein and DNA polymerase ?  

UK PubMed Central (United Kingdom)

Werner Syndrome (WS) is an inherited disease characterized by premature onset of aging, increased cancer incidence, and genomic instability. The WS gene encodes a 1,432-amino acid polypeptide (WRN)...Full Text Available

2000-04-25

336

Exploring nervous system transcriptomes during embryogenesis and metamorphosis in Xenopus tropicalis using EST analysis  

UK PubMed Central (United Kingdom)

BackgroundThe western African clawed frog Xenopus tropicalis is an anuran amphibian species now used as model in vertebrate comparative genomics. It provides the...Full Text Available

337

Evidence That Two Major Replicons Comprise the Genome of Staphylococcus Aureus.  

Science.gov (United States)

In Staphylococcus aureus, a pronounced shift in position of the acriflavin resistance locus was observed when gene order was determined by marker frequency analysis of cells of various ages. In young cells (2-hour culture), acriflavin resistance was mappe...

1967-01-01

338

Distinct signatures of diversifying selection revealed by genome analysis of respiratory tract and invasive bacterial populations  

UK PubMed Central (United Kingdom)

Many pathogens colonize different anatomical sites, but the selective pressures contributing to survival in the diverse niches are poorly understood. Group A Streptococcus (GAS) is...Full Text Available

2011-03-22

339

Differentiation of trophoblast stem cells into giant cells is triggered by p57/Kip2 inhibition of CDK1 activity  

UK PubMed Central (United Kingdom)

Genome endoreduplication during mammalian development is a rare event for which the mechanism is unknown. It first appears when fibroblast growth factor 4 (FGF4) deprivation induces differentiation...Full Text Available

2008-11-01

340

Dietary factors related to body weight in adult Vietnamese in the rural area of Haiphong, Vietnam: the Korean Genome and Epidemiology Study (KoGES)  

UK PubMed Central (United Kingdom)

The objectives of this study were to examine the association between dietary factors and underweight and overweight adult Vietnamese living in the rural areas of Vietnam. A cross-sectional study of...Full Text Available

2010-06-01

341

Detection of Streptococcus mutans Genomic DNA in Human DNA Samples Extracted from Saliva and Blood  

UK PubMed Central (United Kingdom)

Caries is a multifactorial disease, and studies aiming to unravel the factors modulating its etiology must consider all known predisposing factors. One major factor is bacterial colonization,...Full Text Available

2011-01-01

342

DNA Damage during G2 Phase Does Not Affect Cell Cycle Progression of the Green Alga Scenedesmus quadricauda  

UK PubMed Central (United Kingdom)

DNA damage is a threat to genomic integrity in all living organisms. Plants and green algae are particularly susceptible to DNA damage especially that caused by UV light, due to their light dependency...Full Text Available

343

Comprehensive molecular cytogenetic analysis of sorghum genome architecture: distribution of euchromatin, ...  

Science.gov (United States)

Cyteogenetic maps of sorghum chromosomes 3-7, 9, and 10 were constructed on the basis of the fluorescence in situ hybridization (FISH) of ~ ... regions of heterchromatin were delimited for all 10 sorghum chrom...

344

Complete chloroplast genome of Oncidium Gower Ramsey and evaluation of molecular markers for identification and breeding in Oncidiinae  

UK PubMed Central (United Kingdom)

BackgroundOncidium spp. produce commercially important orchid cut flowers. However, they are amenable to intergeneric and inter-specific crossing making phylogenetic...Full Text Available

345

Complete characterization of the edited transcriptome of the mitochondrion of Physarum polycephalum using deep sequencing of RNA  

UK PubMed Central (United Kingdom)

RNAs transcribed from the mitochondrial genome of Physarum polycephalum are heavily edited. The most prevalent editing event is the insertion of single Cs, with Us and dinucleotides...Full Text Available

2011-08-01

346

Comparative genomics reveals 104 candidate structured RNAs from bacteria, archaea, and their metagenomes  

UK PubMed Central (United Kingdom)

BackgroundStructured noncoding RNAs perform many functions that are essential for protein synthesis, RNA processing, and gene regulation. Structured RNAs can be detected by comparative...Full Text Available

2010-01-01

347

Comparative Transcriptional and Genomic Analysis of Plasmodium falciparum Field Isolates  

UK PubMed Central (United Kingdom)

Mechanisms for differential regulation of gene expression may underlie much of the phenotypic variation and adaptability of malaria parasites. Here we describe transcriptional variation among culture-adapted...Full Text Available

2009-10-01

348

Common genetic variation and susceptibility to partial epilepsies: a genome-wide association study  

UK PubMed Central (United Kingdom)

Partial epilepsies have a substantial heritability. However, the actual genetic causes are largely unknown. In contrast to many other common diseases for which genetic association-studies have successfully...Full Text Available

2010-07-01

349

Common Familial Colorectal Cancer Linked to Chromosome 7q31: a genome-wide analysis  

UK PubMed Central (United Kingdom)

Present investigations suggest that approximately 30% of colorectal cancer (CRC) cases arise on the basis of inherited factors. We hypothesize that the majority of inherited factors are moderately...Full Text Available

2008-11-01

350

Chiropteran types I and II interferon genes inferred from genome sequencing traces by a statistical gene-family assembler  

UK PubMed Central (United Kingdom)

BackgroundThe rate of emergence of human pathogens is steadily increasing; most of these novel agents originate in wildlife. Bats, remarkably, are the natural reservoirs of many...Full Text Available

351

Capture of genomic DNA on glass microscope slides  

UK PubMed Central (United Kingdom)

It is well known that DNA strands bind to silica surfaces in the presence of high concentrations of chaotropic salts. We developed simple methods to evaluate binding and recovery of DNA on flat...Full Text Available

2007-06-15

352

Breaking the 1000-gene barrier for Mimivirus using ultra-deep genome and transcriptome sequencing  

UK PubMed Central (United Kingdom)

BackgroundMimivirus, a giant dsDNA virus infecting Acanthamoeba, is the prototype of the mimiviridae family, the latest addition to the family of the nucleocytoplasmic...Full Text Available

353

Blood leukocyte DNA hypomethylation and gastric cancer risk in a high-risk Polish population  

UK PubMed Central (United Kingdom)

Global hypomethylation has been shown to increase genome instability potentially leading to increased cancer risk. We determined whether global methylation in blood leukocyte DNA was associated...Full Text Available

2010-10-15

354

Analysis of the genome-wide variations among multiple strains of the plant pathogenic bacterium Xylella fastidiosa  

UK PubMed Central (United Kingdom)

BackgroundThe Gram-negative, xylem-limited phytopathogenic bacterium Xylella fastidiosa is responsible for causing economically important diseases in grapevine,...Full Text Available

355

Analysis of genomic differences among Clostridium botulinum type A1 strains  

UK PubMed Central (United Kingdom)

BackgroundType A1 Clostridium botulinum strains are a group of Gram-positive, spore-forming anaerobic bacteria that produce a genetically, biochemically, and biophysically...Full Text Available

356

Analysis of European mtDNAs for Recombination  

UK PubMed Central (United Kingdom)

The standard paradigm postulates that the human mitochondrial genome (mtDNA) is strictly maternally inherited and that, consequently, mtDNA lineages are clonal. As a result of mtDNA clonality, phylogenetic...Full Text Available

2001-01-01

357

An integrative multi-dimensional genetic and epigenetic strategy to identify aberrant genes and pathways in cancer  

UK PubMed Central (United Kingdom)

BackgroundGenomics has substantially changed our approach to cancer research. Gene expression profiling, for example, has been utilized to delineate subtypes of cancer, and facilitated...Full Text Available

358

An initial comparative map of copy number variations in the goat (Capra hircus) genome  

UK PubMed Central (United Kingdom)

BackgroundThe goat (Capra hircus) represents one of the most important farm animal species. It is reared in all continents with an estimated world population of...Full Text Available

359

An excess of rare genetic variation in ABCE1 among Yorubans and African-American individuals with HIV-1  

UK PubMed Central (United Kingdom)

Signatures of natural selection occur throughout the human genome and can be detected at the sequence level. We have re-sequenced ABCE1, a host candidate gene essential for...Full Text Available

2009-12-01

360

An Integrated Genomics Approach to Define Niche Establishment by Rhodococcus fascians1[C][W][OA  

UK PubMed Central (United Kingdom)

Rhodococcus fascians is a Gram-positive phytopathogen that induces shooty hyperplasia on its hosts through the secretion of cytokinins. Global transcriptomics using microarrays combined...Full Text Available

2009-03-01

361

Altering the ribosomal subunit ratio in yeast maximizes recombinant protein yield  

UK PubMed Central (United Kingdom)

BackgroundThe production of high yields of recombinant proteins is an enduring bottleneck in the post-genomic sciences that has yet to be addressed in a truly rational manner. Typically...Full Text Available

362

Actin-like sequences are present on human X and Y chromosomes.  

UK PubMed Central (United Kingdom)

The human genome contains greater than 20 actin-related sequences, six of which at least are expressed as protein. We have shown by blot hybridization the presence of actin-like sequences on both the...Full Text Available

1984-08-01

363

A supervised approach for predicting patient survival with gene expression data  

UK PubMed Central (United Kingdom)

Rapid development in genomics in recent years has allowed the simultaneous measurement of the expression levels of thousands of genes using DNA microarrays. This has offered tremendous potential...Full Text Available

2010-01-01

364

A piggyBac transposon-based genome-wide library of insertionally mutated Blm-deficient murine ES cells  

UK PubMed Central (United Kingdom)

Cultured mouse or human embryonic stem (ES) cells provide access to all of the genes required to elaborate the fundamental components and physiological systems of a mammalian cell. Chemical or insertional...Full Text Available

2009-04-01

365

A novel role of the aryl hydrocarbon receptor (AhR) in centrosome amplification - implications for chemoprevention  

UK PubMed Central (United Kingdom)

BackgroundCentrosome aberrations can cause genomic instability and correlate with malignant progression in common human malignancies such as breast and prostate cancer. Deregulation...Full Text Available

366

A novel custom high density-comparative genomic hybridization array detects common rearrangements as well as deep intronic mutations in dystrophinopathies  

UK PubMed Central (United Kingdom)

BackgroundThe commonest pathogenic DMD changes are intragenic deletions/duplications which make up to 78% of all cases and point mutations (roughly 20%) detectable...Full Text Available

367

A new perspective on phylogeny and evolution of tetraodontiform fishes (Pisces: Acanthopterygii) based on whole mitochondrial genome sequences: Basal ecological diversification?  

UK PubMed Central (United Kingdom)

BackgroundThe order Tetraodontiformes consists of approximately 429 species of fishes in nine families. Members of the order exhibit striking morphological diversity and radiated...Full Text Available

368

A new evolutionary scenario for the Mycobacterium tuberculosis complex  

UK PubMed Central (United Kingdom)

The distribution of 20 variable regions resulting from insertion-deletion events in the genomes of the tubercle bacilli has been evaluated in a total of 100 strains of Mycobacterium tuberculosis,...Full Text Available

2002-03-19

369

A microarray analysis of the rice transcriptome and its comparison to Arabidopsis  

UK PubMed Central (United Kingdom)

Arabidopsis and rice are the only two model plants whose finished phase genome sequence has been completed. Here we report the construction of an oligomer microarray based on the presently...Full Text Available

2005-09-01

370

A genomic and proteomic investigation of the impact of preimplantation factor on human decidual cells  

UK PubMed Central (United Kingdom)

OBJECTIVEPreimplantation factor (PIF) is a novel, 15 amino acid peptide, secreted by viable embryos. This study aims to elucidate PIF’s effects in human endometrial...Full Text Available

2010-05-01

371

A genome-wide study of PDZ-domain interactions in C. elegans reveals a high frequency of non-canonical binding  

UK PubMed Central (United Kingdom)

BackgroundProteins may evolve through the recruitment and modification of discrete domains, and in many cases, protein action can be dissected at the domain level. PDZ domains are...Full Text Available

372

A Response Regulator That Represses Transcription of Several Virulence Operons in the Group A Streptococcus  

UK PubMed Central (United Kingdom)

A search for homologs of the Bacillus subtilis PhoP response regulator in the group A streptococcus (GAS) genome revealed three good candidates. Inactivation of one of these, recently...Full Text Available

1999-06-01

373

A Proposal for a Coordinated Effort for the Determination of Brainwide Neuroanatomical Connectivity in Model Organisms at a Mesoscopic Scale  

UK PubMed Central (United Kingdom)

In this era of complete genomes, our knowledge of neuroanatomical circuitry remains surprisingly sparse. Such knowledge is critical, however, for both basic and clinical research into brain function....Full Text Available

2009-03-01

374

A Coxiella burnetti repeated DNA element resembling a bacterial insertion sequence.  

UK PubMed Central (United Kingdom)

A DNA fragment located on the 3' side of the Coxiella burnetii htpAB operon was determined by Southern blotting to exist in approximately 19 copies in the Nine Mile I genome. The DNA sequences of this...Full Text Available

1992-09-01

375

Search for a Methanopyrus-proximal last universal common ancestor based on comparative-genomic analysis  

British Library Electronic Table of Contents (United Kingdom)

The origin of life is a long-standing mystery puzzling many people. This mystery possesses not only philosophical but also important biological significance. To unveil this mystery, the searches for the root of life, or the last universal common ancestor (LUCA), based on comparative-genomic analysis have been intensively performed on rRNAs, tRNAs and proteins sequences. The current search pointed to a Methanopyrus-proximal LUCA, which opens up the reconstruction of Lucan biology and helps to delineate the evolutionary pathways.

2011-01-01

376

Genome Sequence of a Lancefield Group C Streptococcus zooepidemicus Strain Causing Epidemic Nephritis: New Information about an Old Disease  

Science.gov (United States)

Outbreaks of disease attributable to human error or natural causes can provide unique opportunities to gain new information about host-pathogen interactions and new leads for pathogenesis research. Poststreptococcal glomerulonephritis (PSGN), a sequela of infection with pathogenic streptococci, is a common cause of preventable kidney disease worldwide. Although PSGN usually occurs after infection with group A streptococci, organisms of Lancefield group C and G also can be responsible. Despite decades of study, the molecular pathogenesis of PSGN is poorly understood. As a first step toward gaining new information about PSGN pathogenesis, we sequenced the genome of Streptococcus equi subsp. zooepidemicus strain MGCS10565, a group C organism that caused a very large and unusually severe epidemic of nephritis in Brazil. The genome is a circular chromosome of 2,024,171 bp. The genome shares extensive gene content, including many ...

2008-08-21

377

Proceedings of the 1997 oil heat technology conference and workshop  

Energy Technology Data Exchange (ETDEWEB)

This report documents the Proceedings of the 1997 Oil Heat Technology Conference and Workshop, held on April 3--4 at Brookhaven National Laboratory (BNL), and sponsored by the US Department of Energy--Office of Building Technologies, State and Community programs (DOE-BTS), in cooperation with the Petroleum Marketers Association of America (PMAA). This Conference is a key technology transfer activity supported by the ongoing Combustion Equipment Technology (Oil-Heat R and D) program at BNL, and is aimed at providing a forum for the exchange of information among international researchers, engineers, manufacturers, and marketers of oil-fired space-conditioning equipment. The objectives of the Conference were to: identify and evaluate the state-of-the-art and recommend new initiatives for higher efficiency, a cleaner environment, and to satisfy consumer needs cost-effectively, reliably, and safely: and foster cooperation among ...

1997-09-01

378

Conference on reformation of regulation in OECD/IEA power sector - Conference on reformation of regulation in USA, Netherlands, Japan  

Energy Technology Data Exchange (ETDEWEB)

Since 1995, OECD started to examine the current situation of government regulation in each member country and discussed to recommend quality improvement of regulation to member countries. The conference on reformation of regulation in power industry was held in October and December 1998. In USA, enhancing competition in supplying electricity was recommended by eliminating differentiation in use of power network, transmission network and incidental facilities. The retail competition is also an important reformation. The reformation in Netherlands can be seen as following EU guide for revealing problems of the existing regulation in the power industry and for opening up a power market. The Dutch government passed the power act for opening up a market to the public between 1999 and 2007. In Japan, the entry of independent power provider (IPP) has been softened. With the opening of bid system in 1999, bids will be equally given to both power providers and independent ...

1999-01-01

379

Co-Authorship Networks in the Digital Library Research Community  

CERN Document Server

The field of digital libraries (DLs) coalesced in 1994: the first digital library conferences were held that year, awareness of the World Wide Web was accelerating, and the National Science Foundation awarded $24 Million (U.S.) for the Digital Library Initiative (DLI). In this paper we examine the state of the DL domain after a decade of activity by applying social network analysis to the co-authorship network of the past ACM, IEEE, and joint ACM/IEEE digital library conferences. We base our analysis on a common binary undirectional network model to represent the co-authorship network, and from it we extract several established network measures. We also introduce a weighted directional network model to represent the co-authorship network, for which we define $AuthorRank$ as an indicator of the impact of an individual author in the network. The results are validated against conference program committee members in the same ...

2005-01-01

380

The internationalization of nuclear law. 10th regional conference of the German national group of AIDN/INLA held in Celle; Die Internationalisierung des Atomrechts. 10. Regionaltagung der Deutschen Landesgruppe der AIDN/INLA in Celle  

Energy Technology Data Exchange (ETDEWEB)

The German National Group of the International Nuclear Law Association, AIDN/INLA, held its 10{sup th} regional conference in Celle on September 2 and 3, 2004. The event was attended by approx. 120 participants from twenty countries discussing 'the Internationalization of Nuclear Law'. Four sessions were devoted to in-depth studies of these topics: - Legal problems associated with the management of radioactive waste. - Regional nuclear safety vs. global nuclear safety. Do the Europeans need a supplementary EU regime of nuclear safety? - Liability and insurance in cases of nuclear damage. - Topical issues of German nuclear law. (orig.)

2004-10-01

381

Proceedings of the phytoremediation technical seminar  

International Nuclear Information System (INIS)

The research and development efforts regarding phytoremediation technologies were the main focus of this conference. Phytoremediation is the term for any applied process that uses green plants and their associated microorganisms for remediating contaminated soils and groundwater. The 12 papers presented at this conference provided guidance on recommended requirements for the successful implementation of specific phytoremediation technologies. The mechanisms of phytoremediation for petroleum hydrocarbons were also described. Phytoremediation technologies are divided into two major classes including contaminant removal and contaminant stabilization. Several studies have shown that phytoremediation is effective in degrading, containing and transferring petroleum hydrocarbons in soil and groundwater. Phytoremediation has shown to hold promise for the effective and inexpensive cleanup of various hazardous wastes. refs., tabs., figs.

382

Petroleum hydrocarbons and organic chemicals in ground water -- prevention, detection and restoration: Proceedings. Ground water management: Book 17  

International Nuclear Information System (INIS)

The 1993 Petroleum Hydrocarbons Conference was comprised of 3 days of technical presentations within the following topic areas: pollution prevention and cost control; development of remediation levels; free-phase and dissolved hydrocarbon contamination management; investigation and analysis of petroleum hydrocarbons; applications of computer modeling for remediation; design and implementation of bioventing; design and implementation of air sparging; soil vapor extraction as a remediation technique; and ground water remediation using natural bacteria. In addition, more than 100 leading companies in the ground water and petroleum industries participated in the Conference Exposition in which a variety of equipment and services for preventing, detecting and remediating ground water contaminated by petroleum hydrocarbons and other organic chemicals was showcased. Individual papers have been processed separately for inclusion in the appropriate data ...

1993-11-10

383

New models needed to manage gas supply, APPrO conference hears  

International Nuclear Information System (INIS)

Details of a 1 day conference designed to create more efficient interactions between the gas supply and electricity systems in Ontario and new models for gas supply and the electricity system were presented. Market efficiency, generators' perspectives on critical gas issues, an overview of the North American gas and an outline of issues concerning Ontario were discussed. A natural gas industry forecast and issues concerning marketers and producers were presented. The terms on which gas is bought and sold were discussed. Regulatory tools, cost allocation and issues relating to unbundling were also presented. Infrastructure needs were reviewed, as well as basic market structures. It was suggested that appropriate commercial service options need to be developed and approved, including cross-utility services.

2005-08-01

384

Needs, opportunities, and options for large scale systems research  

Energy Technology Data Exchange (ETDEWEB)

The Office of Energy Research was recently asked to perform a study of Large Scale Systems in order to facilitate the development of a true large systems theory. It was decided to ask experts in the fields of electrical engineering, chemical engineering and manufacturing/operations research for their ideas concerning large scale systems research. The author was asked to distribute a questionnaire among these experts to find out their opinions concerning recent accomplishments and future research directions in large scale systems research. He was also requested to convene a conference which included three experts in each area as panel members to discuss the general area of large scale systems research. The conference was held on March 26--27, 1984 in Pittsburgh with nine panel members, and 15 other attendees. The present report is a summary of the ideas presented and the recommendations proposed by the attendees.

1984-10-01

385

Ion nitriding; Proceedings of the International Conference, Cleveland, OH, Sept. 15-17, 1986  

Energy Technology Data Exchange (ETDEWEB)

The present conference discusses plasma-assisted surface coating/modification processes, the applications to date of ion nitriding, the effects of nitrogen on metal surfaces, ion nitriding mechanisms in Cr, Al and Cr + Al-containing 1040 steel, ion nitriding of Al and its alloys, life enhancement for forging dies, novel anode plasma nitriding developments, and a comparative study of the pulsed and dc ion-nitriding behavior in specimens with blind holes. Also discussed are the influence of heating method on ion nitriding, surface hardening of marage steels by ion nitriding without core hardness reduction, plasma nitriding of nodular cast iron sput gears, NbN composites for superconductors, the carburization of tungsten in a glow discharge methane plasma, economic considerations concerning plasma nitriding, and the corrosion properties obtained by ion nitriding.

1987-01-01

386

International Union of Forest Research Organization 19th world congress proceedings  

Energy Technology Data Exchange (ETDEWEB)

An international conference on forestry research presented papers on topics including forest mensuration, growth and yield; growth/yield relationships; design, performance, and evaluation of experiments; forest resource inventory and monitoring techniques; forest management, planning, and managerial economics; forestry and rural development in developing countries; forestry in sustainable economic development; conceptual advances in multiple-use forestry evaluations; economic evaluation of forest damages; supply and demand of roundwood and forest industry products; forestry and rural development in industrialized countries; analysis and evaluation of forest policies; forest institutions and organizations; biological and economic considerations when harvesting young thinning stands; applied sector modelling; and structural changes of the forest sector in a global perspective. Separate abstracts have been prepared for 3 papers from this ...

1990-01-01

387

International Lens Design Conference, Monterey, CA, June 11-14, 1990, Proceedings  

Energy Technology Data Exchange (ETDEWEB)

The present conference on lens design encompasses physical and geometrical optics, diffractive optics, the optimization of optical design, software packages, ray tracing, the use of artificial intelligence, the achromatization of materials, zoom optics, microoptics and GRIN lenses, and IR lens design. Specific issues addressed include diffraction-performance calculations in lens design, the optimization of the optical transfer function, a rank-down method for automatic lens design, applications of quadric surfaces, the correction of aberrations by using HOEs in UV and visible imaging systems, and an all-refractive telescope for intersatellite communications. Also addressed are automation techniques for optics manufacturing, all-reflective phased-array imaging telescopes, the thermal aberration analysis of a Nd:YAG laser, the analysis of illumination systems, athermalized FLIR optics, and the design of array systems using shared symmetry.

1990-01-01

388

Incorporating Traditional Knowledge in an International Regime on Access to Genetic Resources and Benefit Sharing: Problems and Prospects  

British Library Electronic Table of Contents (United Kingdom)

The Seventh Meeting of the Conference of the Parties (2004) of the Convention on Biological Diversity established a mandate for the negotiation of an international regime on Access to Genetic Resources and Benefit Sharing arising from their utilization. Negotiations have been proceeding and have entered the final phase. Seven working group meetings have been held to date and there is expectation that an instrument will emerge by the final deadline - the Tenth Meeting of the Conference of the Parties in Nagoya, Japan in October 2010. A key component singled out for inclusion in the international regime relates to the recognition and protection of the rights of indigenous and local communities (ILCs) over their traditional knowledge (TK) associated with genetic resources. The Ninth Meeting o...

2010-01-01

389

How Women Cope: Being a Numerical Minority in a Male-Dominated Profession  

British Library Electronic Table of Contents (United Kingdom)

Women who have academic careers in engineering have successfully navigated the social identity threats that prevent many other women from feeling that they belong in science, technology, engineering, and math fields. In this research, we examined what factors may be related to resilience in these academic environments. Female academics in engineering and nonengineering fields watched a fictitious conference video depicting either an unbalanced ratio of men to women or a balanced ratio. Subjective measures of identity threat were collected. Past experience with discrimination, positive experience with female role models, family support, and general social support were associated with a greater sense of belonging to or desire to participate in the conference. These variables all buffered neg...

2011-01-01

390

Healthy buildings and installations. Trends at the Healthy Buildings Conference 2003; Gezonde gebouwen en installaties. Trends op Healthy Buildings 2003  

Energy Technology Data Exchange (ETDEWEB)

At the 7th Healthy Buildings Conference, which was held in Singapore, 7-11 December 2003, more than 500 articles to improve public health and productivity of workers in buildings and the performance of installations. Special attention is paid to indoor air quality and thermal comfort in relation to energy efficiency. [Dutch] Op de laatste Healthy Buildings conferentie, december 2003 in Singapore, werden meer dan 500 artikelen gepresenteerd over het creeren van gezonde, productiviteit verhogende gebouwen en installaties. Deze keer lag de nadruk op binnenluchtkwaliteit en thermisch binnenklimaat, onder andere op het aspect energiezuinigheid. Opvallend was ook de aandacht die de problemen met binnenluchtkwaliteit in ontwikkelingslanden kreeg.

2004-02-01

391

Fifth international scientific conference ?Sviridov?s Readings-2010? (Minsk, Republic of Belarus, April 6?9, 2010)  

British Library Electronic Table of Contents (United Kingdom)

The author analyzes conference materials, emphasizing the studies and latest developments useful for industrial heterogeneous catalysis in view of the requirements of green chemistry. Industrial catalysts is developing along a nanometer scale, so especial attention is devoted to analyzing the reports in the Nanochemistry section on the creation of nanocatalysts, the production of active phase nanoparticles, and the formation of new synthesized material properties. The catalysts developed earlier by Russian research in cooperation with Belarusian scientists are considered, and it is shown that not only are expensive nanocontacts extremely promising for industry, but the efficient and economic low-percentage new generation of nanocatalysts synthesized by wet chemistry and containing nanopart...

2010-01-01

392

Fate of volatile organic compounds in wastewater collection systems, volumes IV-VIII  

Energy Technology Data Exchange (ETDEWEB)

This publication compiles five documents on volatile organic compounds (VOCs) in wastewater collection systems. The first is a thesis describing experiments conducted to obtain parameters for determining the significance of biodegradation relative to volatilization as a VOC fate mechanism in sewers. The second is a compilation of three papers from the 1992-94 conferences of the Air & Waste Management Association (AWMA). The papers concern VOC emissions at sewer drop structures and an estimation method for determining VOC emissions from industrial sewers. The third is a compilation of two papers from the AWMA 1992 and 1994 conferences, covering the formation of chloroform from household sources. The fourth is a thesis on post-discharge formation of chloroform in untreated municipal wastewater. The final document is a report detailing the derivation of fate mechanism models in the TOXCHEM model.

1994-12-31

393

DGMK conference 'Energetic utilisation and recycling of waste and biomass'. Authors' manuscripts; Beitraege zur DGMK-Fachbereichstagung 'Energetische und stoffliche Nutzung von Abfaellen und Biomassen'. Autorenmanuskripte  

Energy Technology Data Exchange (ETDEWEB)

This conference of Deutsche Wissenschaftliche Gesellschaft fuer Erdoel, Erdgas und Kohle focused on energetic utilisation and recycling of waste materials and biomass, i.e. combustion, gasification and pyrolysis. Aspects of process control were gone into as well. [German] Die Fachbereichstagung der Deutschen Wissenschaftlichen Gesellschaft fuer Erdoel, Erdgas und Kohle beschaeftigte sich mit der energetischen und stofflichen Nutzung von Abfall und Biomasse. Verbrennung, Vergasung und Pyrolyse verschiedener Abfallstoffe sowie die Prozesssteuerung wurden eroertert.

2000-07-01

394

Coastal sediments '91. Volume 1  

Energy Technology Data Exchange (ETDEWEB)

This volume contains papers delivered at a technical conference of the American Society of Civil Engineers held on June 25-27, 1991 in Seattle, Washington. The conference dealt with the physical aspects of sediment processes in the coastal environment. The papers are presented under three general themes: fundamentals of coastal sediment transport, coastal geologic processes, and engineering applications. The topics of the role of long waves in coastal sediment processes and cross-shore transport are highlighted. Examples of the topics covered include: sediment transport; beach and nearshore sedimentation; shoreline and beach profile changes; longshore and cross-shore transport; storm erosion; inlet sediment processes; gravel transport; coastal structure and sediment interaction; and dredging.

1991-01-01

395

BMBF status seminar: Bodies of landfills. Vol. 1. Conference report; BMBF-Statusseminar: Deponiekoerper. Bd. 1. Tagungsband  

Energy Technology Data Exchange (ETDEWEB)

This conference report contains the lectures presented at the BMBF status seminar on the cooperative project ``Bodies of landfills``, which took place at Wuppertal on 25th and 26th April 1995. The cooperative project was started in autumn 1993 and studies the long-term behaviour of wastes deposited at landfills in general. Inorganic and municipal wastes are studied separately. (orig./SR) [Deutsch] Der vorliegende Tagungsband enthaelt die Vortraege des BMBF-Statusseminars zum Verbundvorhaben `Deponiekoerper` vom 25. und 26. April 1995 in Wuppertal. Das Verbundvorhaben `Deponiekoerper` wurde im Herbst 1993 begonnen und befasst sich ganz generell mit dem langfristigen Deponieverhalten von Abfaellen. Es ist unterteilt in die Untersuchung von anorganischen Abfaellen und von Siedlungsabfaellen. (orig./SR)

1995-12-31

396

The enhanced genomic instability was induced by alpha particle and low-energy ion irradiation in somatic cells of Arabidopsis thaliana  

International Nuclear Information System (INIS)

Although low-energy ion radiation has been proven to have a wide range of biological effects and led to fruitful achievements as a new mutagenic source for genetic modification, there still exist some disputes about its mutagenic mechanisms because of its short-penetrating property. In present research, Arabidopsis thaliana transgenic for GUS recombination substrate was used to evaluate the genomic instability induced by irradiations of alpha particle (3.3MeV) and Low-energy-Argon ion (30 KeV). A pronounced effects of alpha particle irradiation to Arabidopsis thaliana seedlings and Argon ion irradiation to seeds on the somatic homologous recombination frequency (sHRF) were reported. The sHRFs increased 1.88-fold and 2.42-fold, respectively, which indicated that the short-penetrating radiation could effectively induce the plant genomic instability in either dry seeds or seedlings with active metabolism. The local alpha particle irradiation of ...

2008-08-12

397

Genomic analysis of the symbiotic marine crenarchaeon, Cenarchaeumsymbiosum  

Energy Technology Data Exchange (ETDEWEB)

Crenarchaea are ubiquitous and abundant microbial constituents of soils, sediments, lakes and ocean waters, yet relatively little is known about their fundamental evolutionary, ecological, and physiological properties. To better describe the ubiquitous nonthermophilic Crenarchaea, we analyzed the genome sequence of one representative, the uncultivated sponge symbiont, Cenarchaeum symbiosum. C. symbiosum genotypes coinhabiting the same host partitioned into two dominant populations, corresponding to previously described a- and b-type ribosomal RNA variants. Although synthetic, overlapping a- and b-type ribotypes harbored significant genetic variability. A single tiling path comprising the dominant a-type genotype was assembled, and used to explore the biological properties of C. symbiosum and its planktonic relatives. Out of a total of 2,066 predicted open reading frames, 36% were more highly conserved with other Archaea. The remainder partitioned between bacteria ...

2006-06-24

398

The mouse formin (Fmn) gene: Genomic structure, novel exons, and genetic mapping  

Energy Technology Data Exchange (ETDEWEB)

Mutations in the mouse formin (Fmn) gene, formerly known as the limb deformity (ld) gene, give rise to recessively inherited limb deformities and renal malformations or aplasia. The Fmn gene encodes many differentially processed transcripts that are expressed in both adult and embryonic tissues. To study the genomic organization of the Fmn locus, we have used Fmn probes to isolate and characterize genomic clones spanning 500 kb. Our analysis of these clones shows that the Fmn gene is composed of at least 24 exons and spans 400 kb. We have identified two novel exons that are expressed in the developing embryonic limb bud as well as adult tissues such as brain and kidney. We have also used a microsatellite polymorphism from within the Fmn gene to map it genetically to a 2.2-cM interval between D2Mit58 and D2Mit103. 36 refs., 6 figs., 1 tab.

1997-02-01

399

Genetic effects of introgression genomic components from Sea Island cotton (Gossypium barbadense L.) on fiber related traits in upland cotton (G. hirsutum L.)  

British Library Electronic Table of Contents (United Kingdom)

The germplasm with exotic genomic components especially from Sea Island cotton (Gossypium barbadense L. Gb) is the dominant genetic resources to enhance fiber quality of upland cotton (G. hirsutum L., Gh). Due to low efficiency of phenotypic evaluation and selection on fiber quality, genetic dissection of favorable alleles using molecular markers is essential. Genetic dissection on putative Gb introgressions related to fiber traits were conducted by SSR markers with mapping populations derived from a cross between Luyuan343 (LY343), a superior fiber quality introgression line (IL) with genomic components from Gb, and an elite Upland cotton cv. Lumianyan#22 (LMY22). Among 82 polymorphic loci screened out from 4050 SSRs, 42 were identified as putative introgression alleles. A total of 29 fib...

2011-01-01

400

Gene discovery in the Acanthamoeba castellanii genome  

Energy Technology Data Exchange (ETDEWEB)

Acanthamoeba castellanii is a free-living amoeba found in soil, freshwater, and marine environments and an important predator of bacteria. Acanthamoeba castellanii is also an opportunistic pathogen of clinical interest, responsible for several distinct diseases in humans. In order to provide a genomic platform for the study of this ubiquitous and important protist, we generated a sequence survey of approximately 0.5 x coverage of the genome. The data predict that A. castellanii exhibits a greater biosynthetic capacity than the free-living Dictyostelium discoideum and the parasite Entamoeba histolytica, providing an explanation for the ability of A. castellanii to inhabit adversity of environments. Alginate lyase may provide access to bacteria within biofilms by breaking down the biofilm matrix, and polyhydroxybutyrate depolymerase may facilitate utilization of the bacterial storage compound polyhydroxybutyrate as a food source. Enzymes for the ...

2005-08-01

401

Fiscal 1998 industrial science and technology R and D project. Research report on R and D of genome informatics technology (Development of stable oil supply measures using complex biosystem); 1998 nendo genome informatics gijutsu kenkyu kaihtsu seika hokokusho. Fukugo seibutsukei riyo sekiyu antei kyokyu taisaku kaihatsu  

Energy Technology Data Exchange (ETDEWEB)

This report describes the fiscal 1998 result on development of genome informatics technology. As comparative analysis technique of genes, the combination of electrophoresis and PCR was used. For improvement of the throughput and reproducibility of the technique, module- shuffling primers were used, and the multi(96)-arrayed capillary fragment analyzer was devised. The system detecting SNPs rapidly was also developed successfully. As analysis technology of DNA sequence by use of triple- stranded DNA formation, study was made on construction of long cDNA libraries, selective subtraction of specific sequences from libraries, and the basic technology of homologous cloning. Study was also made on each reaction step of IGCR technique for fast analysis, and specifications of a fluorescence transfer monitor. As modeling technique of genetic sequence information, the simulation model was developed for gene expression regulatory networks during muscle differentiation, and ...

1999-03-01

402

Evolutionary dynamics of Newcastle disease virus  

International Nuclear Information System (INIS)

A comprehensive dataset of NDV genome sequences was evaluated using bioinformatics to characterize the evolutionary forces affecting NDV genomes. Despite evidence of recombination in most genes, only one event in the fusion gene of genotype V viruses produced evolutionarily viable progenies. The codon-associated rate of change for the six NDV proteins revealed that the highest rate of change occurred at the fusion protein. All proteins were under strong purifying (negative) selection; the fusion protein displayed the highest number of amino acids under positive selection. Regardless of the phylogenetic grouping or the level of virulence, the cleavage site motif was highly conserved implying that mutations at this site that result in changes of virulence may not be favored. The coding sequence of the fusion gene and the genomes of viruses from wild birds displayed higher yearly rates of change in virulent viruses than in ...

2009-08-15

403

Complete genome sequence of Conexibacter woesei type strain (ID131577T)  

Energy Technology Data Exchange (ETDEWEB)

The genus Conexibacter (Monciardini et al. 2003) represents the type genus of the family Conexibacteraceae (Stackebrandt 2005, emend. Zhi et al. 2009) with Conexibacter woesei as the type species of the genus. C. woesei is a representative of a deep evolutionary line of des-cent within the class Actinobacteria. Strain ID131577T was originally isolated from temperate forest soil in Gerenzano (Italy). Cells are small, short rods that are motile by peritrichous fla-gella. They may form aggregates after a longer period of growth and, then as a typical charac-teristic, an undulate structure is formed by self-aggregation of flagella with entangled bacteri-al cells. Here we describe the features of the organism, together with the complete sequence and annotation. The 6,359,369 bp long genome of C. woesei contains 5,950 protein-coding and 48 RNA genes and is part of the Genomic Encyclopedia of Bacteria and Archaea project.

2010-01-01

404

The genetic basis of salinity tolerance in Arctic charr (Salvelinus alpinus).  

Science.gov (United States)

ABSTRACT: BACKGROUND: The capacity to maintain internal ion homeostasis amidst changing conditions is particularly important for teleost fishes whose reproductive cycle is dependent upon movement from freshwater to seawater. Although the physiology of seawater osmoregulation in mitochondria-rich cells of fish gill epithelium is well understood, less is known about the underlying causes of inter- and intraspecific variation in salinity tolerance. We used a genome-scan approach in Arctic charr (Salvelinus alpinus) to map quantitative trait loci (QTL) correlated with variation in four salinity tolerance performance traits and six body size traits. Comparative genomics approaches allowed us to infer whether allelic variation at candidate gene loci (e.g., ATP1alpha1b, NKCC1, CFTR, and cldn10e) could have underlain observed variation. RESULTS: Combined parental analyses yielded genome-wide significant QTL on linkage groups 8, 14 ...

2011-09-21

405

{sup 3}He spectrum at small atmospheric depths for different geomagnetic cutoff values  

Energy Technology Data Exchange (ETDEWEB)

It is carried out a calculation to determine the energy spectra of secondary {sup 3}He at small atmospheric depths. It is produced in the spallation reaction of primary helium and heavier nuclei in the overlying atmosphere. It is examined the effect of the geomagnetic cut-off on the spectral shape of the secondary {sup 3}He nuclei. The calculations are being carried out for both solar minimum and maximum periods. Results from these calculations will be presented at the Conference.

1995-09-01

406

miR-9 and let-7g enhance the sensitivity to ionizing radiation by suppression of NF?B1  

UK PubMed Central (United Kingdom)

The activation of nuclear factor-kappa B1 (NFκB1) in cancer cells may confer resistance to ionizing radiation (IR). To enhance the therapeutic efficiency of IR in lung cancer, we screened for...Full Text Available

2011-05-31

407

X ICSMFE: Tenth international conference on soil mechanics and foundation engineering. Vol. 2  

Energy Technology Data Exchange (ETDEWEB)

Topics covered in this volume include soil-structure interactions, environmental control (including waste materials), soil exploration and sampling, and pile foundations. Four papers on the use of fly ash from coal combustion as a construction material have been abstracted separately.

1981-01-01

408

Wolsung-1 nuclear power plant  

International Nuclear Information System (INIS)

The Wolsung-1 CANDU 600 MWe plant is now in operation. This paper provides an update on the design, construction and commissioning progress reported at last year's conference. The accomplishments of the past year are highlighted with emphasis on how the station has been commissioned in preparation for commercial service and on the skills that were dedicated to the completion of the project. The paper also deals with some of the features of the CANDU 600 MWe Nuclear Power Plant that make it viable for export.

1977-06-05

409

USDA Finances Wind for Rural Economic Development (Poster)  

Energy Technology Data Exchange (ETDEWEB)

To foster rural economic development and growth, Congress passed the Renewable Energy Systems and Energy Efficiency Improvements Program as Section 9006 of the 2002 Farm Bill. This program provides financial assistance to farmers, ranchers, and rural small businesses to purchase renewable energy systems or make energy efficiency improvements. The Rural Business and Cooperative Services of the United States Department of Agriculture (USDA) administers this program. This conference poster provides an overview of Section 9006.

2005-05-01

410

The high-temperature reactor's attractiveness lies in passive safety  

International Nuclear Information System (INIS)

In the recent years the use of nuclear energy has turned from a technical and scientific issue to a political one. The high-temperature reactor (HTR) however, has always been advertised as particularly safe. The present situation and future developments of HTR-technology were the two issues that VDI-News brought up on the 27th October on an HTR-conference in an interview with the 'spiritual father' of the HTR, Prof. Dr. Rudolf Schulten of the Juelich Nuclear Research Centre. (orig.).

411

The environmentally sound management of low-grade fuels  

Energy Technology Data Exchange (ETDEWEB)

Selected papers from the conference are presented under seven sections covering: an overview of the environmental and health implications of low-grade fuel use; fuel resources and recovery; exploitation of peat and wood as a fuel; oil shale resources, processing and use; technological approaches to the reduction of environmental impacts associated with oil shale processing and use; technological approaches to reducing the environmental impacts of low-grade coal use; and environmentally sound technical options for low-grade fuel use.

1992-01-01

412

Termine: Stahlbau 4/2010  

British Library Electronic Table of Contents (United Kingdom)

HOAI und Vergabe - erste Erfahrungen mit den Novellen 29. Stahlbauseminar INTAB+ Seminar 2010 Verbundbrucken mit integralen Widerlagern Hamburg Offshore Wind Conference 2010Perfect know-HOW Leichtbausysteme aus Stahl fur Dach und Fassade. Energie- und kosteneffiziente Losungen fur Neu- und Bestandsbau Lubecker Bautag

2010-01-01

413

Solar rises in the south; Le solaire se leve au sud  

Energy Technology Data Exchange (ETDEWEB)

This autumn, Nice welcomed the thirteen European photovoltaic conference. It was the occasion for the world of solar energy to measure technical progress which were carried out and the market which are still to win. If developing countries are a reserve of new markets, they are not solvent and programmes depend on North/South negotiations. (N.C.).

1996-01-01

414

Selective Expression in Carotid Body Type I Cells of a Single Splice Variant of the Large Conductance Calcium- and Voltage-activated Potassium Channel Confers Regulation by AMP-activated Protein Kinase*  

UK PubMed Central (United Kingdom)

Inhibition of large conductance calcium-activated potassium (BKCa) channels mediates, in part, oxygen sensing by carotid body type I cells. However, BKCa channels remain active...Full Text Available

2011-04-08

415

Searches for standard model Higgs at the Tevatron  

Energy Technology Data Exchange (ETDEWEB)

A summary of the latest results of Standard Model Higgs boson searches from CDF and D0 presented at the DIS 2007 conference is reported in this paper. All analyses presented use 1 fb{sup -1} of Tevatron data. The strategy of the different analyses is determined by the Higgs production mechanism and decay channel.

2007-04-01

416

Searches for Standard Model Higgs at the Tevatron  

Energy Technology Data Exchange (ETDEWEB)

A summary of the latest results of Standard Model Higgs boson searches from CDF and D0 presented at the DIS 2007 conference is reported in this paper. All analyses presented use 1 fb{sup -1} of Tevatron data. The strategy of the different analyses is determined by the Higgs production mechanism and decay channel.

2007-11-01

417

Review of the 1996 Pacific Basin Conference and future outlook  

Energy Technology Data Exchange (ETDEWEB)

Highlights of the meeting are briefly summarized in this paper. Most of the papers presented at the meeting dealt with remediation and pollution prevention practices. A major focus of the technical sessions was on the identification of pollution sources. Identification of exposures to specific chemicals with disease outcomes was also discussed. Other papers focused on ecological exposures and their effects on wildlife to identify the presence of contaminants. 4 refs.

1996-12-31

418

Regulatory and technical reports (Abstract Index Journal): Compilation for third quarter 1986, July-September  

Energy Technology Data Exchange (ETDEWEB)

This journal includes all formal reports in the NUREG series prepared by the NRC staff and contractors, as well as proceedings of conferences and workshops. The entries in the compilation are indexed for access by title and abstract, contractor report number, personal author, subject, NRC organization, contractor, and licensed facility.

1986-11-01

419

Regulatory and technical reports (Abstract Index Journal). Annual compilation for 1985. Volume 10, No. 4  

Energy Technology Data Exchange (ETDEWEB)

This journal includes all formal reports in the NUREG series prepared by the NRC staff and contractors, as well as proceedings of conferences and workshops. The entries in the compilation are indexed for access by title and abstract, contractor report number, personal author, subject, NRC organization, contractor, and licensed facility.

1986-02-01

420

Proceedings of the tenth annual DOE low-level waste management conference: Session 1: Institutional and regulatory issues  

Energy Technology Data Exchange (ETDEWEB)

This document contains eleven papers on various aspects of low-level radioactive waste regulation. Topics include: EPA environmental standards; international exemption principles; the concept of below regulatory concern; envirocare activities in Utah; mixed waste; FUSRAP and the Superfund; and a review of various incentive programs. Individual papers are processed separately for the data base. (TEM)

1988-12-01

421

Proceedings of the eighth symposium on training of nuclear facility personnel  

Energy Technology Data Exchange (ETDEWEB)

This conference brought together those persons in the nuclear industry who have a vital interest in the training and licensing of nuclear reactor and nuclear fuel processing plant operators, senior operators, and support personnel for the purpose of an exchange of ideas and information related to the various aspects of training, retraining, examination, and licensing. The document contains 64 papers; each paper was abstracted for the data.

1989-04-01

422

Proceedings of the 1991 ASME JSME thermal engineering joint conference  

International Nuclear Information System (INIS)

This book is organized under the following headings: Electrohydrodynamic heat transfer augmentation; Forced convection augmentation and heat transfer control; Turbulent heat transfer; Thermal problems in the environment; Energy conversion systems; Measurement, visualization, and imaging; Thermal problems in space technology; and Thermal properties.

1991-03-17

423

Proceedings of GeoEdmonton 2008 : the 61. Canadian geotechnical conference and 9. joint CGS/IAH-CNC groundwater conference : a heritage of innovation  

Energy Technology Data Exchange (ETDEWEB)

This conference provided a forum for more than 500 delegates from industry, government universities and research centres to share their professional knowledge on research and development that affects all sectors of geotechnical engineering, applied geology and hydrogeology. Accomplishments in the geoenvironmental field were also highlighted. The geotechnical sessions were entitled: pile foundations and load testing; excavations and special foundation issues; reinforced soil and soil-structure interactions; advances in modelling, constitutive issues; advances in modelling, consolidation and other applications; advances in modelling, discrete elements and slope stability; embankments and dams; landfills and barriers; fundamental soil mechanics; soil mechanics and ground movement; GIS and remote sensing; landslides and slopes; cone penetration tests and liquefaction assessment; rock mechanics; engineering geology; geoenvironmental sustainability; oilsand and petroleum ...

2008-07-01

424

Pharmaceutics | Special Issue: Solid Dosage Forms  

Wastenet

...Pharmaceutics | Special Issue: Solid Dosage Forms LoginRegister mdpi.com Journals A-Z For Authors About Open Access Policy Title / Keyword Journal all Administrative Sciences Agriculture ...Establishing Differences from Adults Recent Developments and Future Perspectives in Dissolution Testing Solid Dosage Forms The 1st Electronic Conference on Pharmaceutical Science The Progress on Pharmaceutics ... 1 (2009) Special Issue \\

425

Performing Re-mediation in Graphical Cyberspace: Mediating Agency, Body and Identity in Virtual Interactional Practices  

DEFF Research Database (Denmark)

Promoted as the first academic conference to be held completely in graphical cyberspace, Avatars 98 took place in November 1998. The virtual conference site was built and inhabited using software that supports multi-party presence over the Internet in a simulated, navigable environment. During the conference, avatar-embodied speakers using text chat performed to virtual audiences, 'webcams' (re)broadcast live video images of CNN and other remote sites, and a 'webcast' sent audiovisual representations captured by video camera of certain key participants in their physical locations. Such a novel and spectacular multi-media event raises many questions. How do we conceive of the recent developments in media technology and social computing that are impacting on what we have traditionally called 'the mass media'? How is interaction and talk mediated and adapted to new media genres? And how do participants construct and maintain ...

426

Offshore and arctic operations symposium - 1987  

Energy Technology Data Exchange (ETDEWEB)

This book presents the papers given at a conference on offshore platforms. Topics considered in this book include risk assessment, crack propagation, fracture control, stress corrosion, the reliability of pile foundations, the thermal conductivity of offshore pipeline coating material, economic analysis, hydrodynamics, simulation, Arctic structure design, composite materials, buoys, deep water drilling, corrosion protection, pollution control equipment, and subsea exhaust gas compressors.

1987-01-01

427

NEW DEVELOPMENT IN THE VACUUM MELTING AND CASTING OF URANIUM IN TONNAGE QUANTITIES. Transactions of the Vacuum Metallurgy Conference, 1960  

Science.gov (United States)

> Develoopments which have imporved fuel core quality and reduced production costs are described. These developments in the melting and casting of uranium ingots arei modification of the crucible and knockout-slide assembly, substitution of uncoated crucibles for coated crucibles, and substitution of a one-piece gun barrel mold for a vertically split mold. (N.W.R.)

1961-01-01

428

Immunological correlates for protection against intranasal challenge of Bacillus anthracis spores conferred by a protective antigen-based vaccine in rabbits.  

Science.gov (United States)

Correlates between immunological parameters and protection against Bacillus anthracis infection in animals vaccinated with protective antigen (PA)-based vaccines could provide surrogate markers to evaluate the putative protective efficiency of immunization in humans. In previous studies we demonstrated that neutralizing antibody levels serve as correlates for protection in guinea pigs (S. Reuveny et al., Infect. Immun. 69:2888-2893, 2001; H. Marcus et al., Infect. Immun. 72:3471-3477, 2004). In this study we evaluated similar correlates for protection by active and passive immunization of New Zealand White rabbits. Full immunization and partial immunization were achieved by single and multiple injections of standard and diluted doses of a PA-based vaccine. Passive immunization was carried out by injection of immune sera from rabbits vaccinated with PA-based vaccine prior to challenge with B. anthracis spores. Immunized rabbits were challenged by intranasal spore instillation with one ...

2006-01-01

429

III International Symposium on analytical methodology in the Environment. III Symposium Internacional de Metodologia Analitica en el campo del medio ambiente  

Energy Technology Data Exchange (ETDEWEB)

The symposium had four areas in analytical methodology to study global environmental change: air; water, wastes and speciation, analytical methodology and environmental management. The symposium had 24 conferences and papers.

1994-01-01

430

IAEA Nuclear Security Programme Combating Nuclear Terrorism  

International Nuclear Information System (INIS)

IAEA Plans of activities include, General Conference in September 2001 which reviewed activities relevant to preventing nuclear terrorism and proposed master plan. The Board of Governors approved new Nuclear Security Plan for the next four years. Three activity areas are; - needs assessment, analysis and coordination, prevention and detection and response.

2010-05-10

431

Heat transfer  

Energy Technology Data Exchange (ETDEWEB)

Heat transfer has emerged as a leading-edge technology supporting the rapid pace of developments in science and engineering ranging from energy production to electronic cooling. Subjects covered at the 6th UK National Conference on heat transfer held at Edinburgh from 15-16 September 1999 include: convection; boiling and evaporation; condensation; numerical techniques; heat exchangers; radiation and combustion; conduction; two-phase flow and heat transfer augmentation. Fifteen of the papers are abstracted here.

1999-07-01

432

Healthy buildings '88. Volume 2. Planning, physics, and climate technology for healthier buildings (Planning, physique et technologie du climat pour des constructions plus saines)  

Energy Technology Data Exchange (ETDEWEB)

The Conference on Building Design and Architecture organized by Swedish Council for Building Research Contents included articles on building physics, thermal-climate technology, and building location and planning.

1988-06-01

433

Healthy buildings '88. Volume 1. State-of-the-art reviews (Revue de l'etat de la technique)  

Energy Technology Data Exchange (ETDEWEB)

The Conference on Building Design and Architecture organized by Swedish Council for Building Research Contents included articles on building physics, thermal-climate technology, indoor-air-quality technology, construction materials, quality assurance, and building policy and regulation.

1988-06-01

434

Getting to grips with remote handling and robotics  

International Nuclear Information System (INIS)

A report on the Canadian Nuclear Society Conference on robotics and remote handling in the nuclear industry, September 1984. Remote handling in reactor operations, particularly in the Candu reactors is discussed, and the costs and benefits of use of remote handling equipment are considered. Steam generator inspection and repair is an area in which practical application of robotic technology has made a major advance. (U.K.).

435

Fifty successful years of the Institute of Plasma Physics, Academy of Sciences of the Czech Republic  

International Nuclear Information System (INIS)

The history of the Czech Institute of Plasma Physics is highlighted. The article is structured as follows: Cyclic accelerators; Interaction of an external high-frequency field and high-temperature plasma - the tokamak; Interaction of an external high-frequency field and high-temperature plasma - pulse plasma systems; Low-temperature plasma - plasma technologies and new materials; Laser plasma - PALS; Optical diagnosis; and Teaching, conferences and international cooperation. (P.A.)

436

Eighth ocean energy conference: preliminary report  

Energy Technology Data Exchange (ETDEWEB)

A series of speeches is presented which cover political aspects of ocean energy, legislation, the status of the DOE Ocean Energy Program, the Maritime Administration OTEC Support Program. Six workshop reports are given covering ocean energy technology and systems concepts, power systems concepts, environmental developments, energy transfer and utilization, construction and test capabilities, and industry development. (LEW)

1981-01-01

437

Case for Sizewell B  

Energy Technology Data Exchange (ETDEWEB)

A review and a number of extracts are given of the statement made by the acting chairman of the CEGB at a press conference on the publication of documents in support of the case for the building of the proposed Sizewell B PWR. The documents comprise the CEGB Statement of Case proper, the Reference Design, the Pre-Construction Safety Report and some 300 supporting reports. Objectors have eight months to study the reports before the public inquiry into the CEGB's proposals due to open in January 1983.

1982-07-01

438

Caesium clocks. Status and research activities  

International Nuclear Information System (INIS)

Thirty years ago, in 1967, the new definition of the second based on a quantum phenomenon, the hyperfine splitting of the groundstate of the "1"3"3Cs atom, was passed by the 13th General Conference on Weight and Measure. What followed was a fascinating improvement of the performance of caesium clocks which is still pursued. Their total uncertainty could be reduced, until 1995, by 4 orders of magnitude. With the development of the so-called fountain clocks, another factor of ten is within reach. (orig.)

1998-02-01

439

CEEweb for Biodiversity  

Wastenet

...relevant international NGO networks Lobby for sufficient support in EU institutions for developing EU legislation on IAS Provide input into the debate about the wilderness concept at the Wilderness Conference under the Czech Presidency National level press work on Art. 17 composite report and Natura 2000 management CEEweb Natura 2000 Working Group meetings Develop a CEEweb proposal on how to discuss and ensure the appropriate management of Natura 2000 sites on ...

440

Binding of Ru(bpy)2(eilatin)2+ to Matched and Mismatched DNA  

UK PubMed Central (United Kingdom)

The DNA-binding properties of Ru(bpy)2(eilatin)2+ have been investigated to determine if the sterically expansive eilatin ligand confers specificity for destabilized single-base...Full Text Available

2008-07-21

441

B(s) properties at the Tevatron  

Energy Technology Data Exchange (ETDEWEB)

The Tevatron collider at Fermilab provides a very rich environment for the study B{sub s} mesons. In this paper they show a few selected topics from the CDF and D0 collaborations, giving special attention to the B{sub s} Mixing analyses. This note corresponds to the proceedings of the Hadron Collider Physics 2005 conference.

2005-11-01

442

Assisting Eastern European countries in the setting up of a national response to nuclear smuggling  

International Nuclear Information System (INIS)

The paper will report the experience gained in the implementation of the national assistance projects, including the detailed assessment of the national situation compared to the ITWG Model Action Plan, the upgrading of the technical skills, the training of national experts and the joint analysis of nuclear material at ITU. The status of the work with the 13 future Member States to the European Union will also be reported on during the conference

2001-10-01

443

Aspen Winter Conference Series  

Science.gov (United States)

(B204) The meeting will bring together observers and theorists in a highly interactive format, to further connect the local and cosmological star formation communities. Forward looking talks, aimed at the other communities, will survey terminology, achievements, problems and aspirations. Discussion will focus on the definition of the key questions, how the different communities can help each other, and preparations for the incorporation of realistic star formation into cosmological simulations.

1999-01-01

444

Ancillary Services in a pool-based competitive market: Conference on innovative approaches to electricity pricing  

Energy Technology Data Exchange (ETDEWEB)

(1) Most ancillary services needed for real-time control of the transmission grid and to meet operating criteria can be competitively supplied and competitively procured. (2) The independent service operator (ISO) must directly control the generators and loads, which supply ancillary services. (3) Comparability of access to ancillary services is achievable through the ISO-based competitive market structure.

1996-03-01

445

Universal Similarity  

CERN Document Server

We survey a new area of parameter-free similarity distance measures useful in data-mining, pattern recognition, learning and automatic semantics extraction. Given a family of distances on a set of objects, a distance is universal up to a certain precision for that family if it minorizes every distance in the family between every two objects in the set, up to the stated precision (we do not require the universal distance to be an element of the family). We consider similarity distances for two types of objects: literal objects that as such contain all of their meaning, like genomes or books, and names for objects. meaning, like genomes or books, and names for objects. The latter may have literal embodyments like the first type, but may also be abstract like ``red'' or ``christianity.'' For the first type we consider a family of computable distance measures corresponding to parameters expressing similarity according to particular features between ...

2005-01-01

446

Summary of the OA biomarkers workshop 2010 - genetics and genomics: new targets in OA  

British Library Electronic Table of Contents (United Kingdom)

On November fourth and fifth 2010 a group of more than 100 international investigators gathered in Atlanta for the second Osteoarthritis (OA) Biomarkers Global Initiative workshop titled ''Genetics and Genomics: New Targets in OA''. The first workshop took place in April 2009 and focused on in vitro (soluble) biomarkers whilst the third and final workshop will take place in 2012 and will focus on imaging biomarkers. The OA Research Society International (OARSI) has organized the workshops. In addition to OARSI, the National Institute of Arthritis, Musculoskeletal and Skin Diseases, the Arthritis Foundation, Amgen, Genzyme, the American Orthopaedic Society for Sports Medicine and Pfizer sponsored the second meeting. It was clear from this meeting that experiments in the genetics, epigenetic...

2011-01-01

447

Selective changes of retroelement expression in human prostate cancer  

British Library Electronic Table of Contents (United Kingdom)

Retroelements constitute a large part of the human genome. These sequences are mostly silenced in normal cells, but genome-wide DNA hypomethylation in cancers might lead to their re-expression. Whether this re-expression really occurs in human cancers is largely unkown. We therefore investigated expression and DNA methylation of several classes of retroelements in human prostate cancer tissues and cell lines by quantitative reverse transcription-polymerase chain reaction and pyrosequencing, respectively. The most striking finding was strong and generalized increased expression of the HERV-K_22q11.23 provirus in cancers, including de novo expression of a spliced accessory Np9 transcript in some tumors. In parallel, DNA methylation in the long terminal repeat (LTR) decreased. Conversely, HER...

2011-01-01

448

Introduction to the Special Issue: Human Linkage Studies for Behavioral Traits  

British Library Electronic Table of Contents (United Kingdom)

In the post Genome era, the aim of behavior genetics has shifted from estimating the relative contributions of genes and environmental factors to (co-)variation in human complex traits, to localization of genes and identification of functional genetic variants. This special issue reflects this transition and presents fifteen papers that report on genome-wide linkage scans for complex traits in humans and on methodological tools and innovations. Six papers focus on cognition and report overlapping linkage peaks on chromosomes 6p and 14p. Papers on addictive behavior, i.e. smoking and alcohol dependence and its endophenotypes, find moderate LOD scores on chromosomes 6p, 5q, 4p and 7q, respectively. Three papers concentrate on emotionality, depression and loneliness and examine chromosomes 2q...

2006-01-01

449

Genomic architecture of aggression: Rare copy number variants in intermittent explosive disorder  

British Library Electronic Table of Contents (United Kingdom)

Abstract Copy number variants (CNVs) are known to be associated with complex neuropsychiatric disorders (e.g., schizophrenia and autism) but have not been explored in the isolated features of aggressive behaviors such as intermittent explosive disorder (IED). IED is characterized by recurrent episodes of aggression in which individuals act impulsively and grossly out of proportion from the involved stressors. Previous studies have identified genetic variants in the serotonergic pathway that play a role in susceptibility to this behavior, but additional contributors have not been identified. Therefore, to further delineate possible genetic influences, we investigated CNVs in individuals diagnosed with IED and/or personality disorder (PD). We carried out array comparative genomic hybridizati...

2011-01-01

450

Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease  

British Library Electronic Table of Contents (United Kingdom)

Meningococcal disease is an infection caused by Neisseria meningitidis. Genetic factors contribute to host susceptibility and progression to disease, but the genes responsible for disease development are largely unknown. We report here a genome-wide association study for host susceptibility to meningococcal disease using 475 individuals with meningococcal disease (cases) and 4,703 population controls from the UK. We performed, in Western European and South European cohorts (consisting of 968 cases and 1,376 controls), two replication studies for the most significant SNPs. A cluster of complement factor SNPs replicated independently in both cohorts, including SNPs within complement factor H (CFH) (rs1065489 (p.936D

2010-01-01

451

Complete genome sequences of Brucella melitensis strains M28 and M5-90, with different virulence backgrounds.  

Science.gov (United States)

Brucella melitensis is a Gram-negative coccobacillus bacteria belonging to the Alphaproteobacteria subclass. It is an important zoonotic pathogen that causes brucellosis, a disease affecting sheep, cattle, and sometimes humans. The B. melitensis strain M5-90, a live attenuated vaccine cultured from the B. melitensis virulent strain M28, has been an effective tool to control brucellosis in goats and sheep in China. Here we report the complete genome sequences of B. melitensis M28 and M5-90, strains with different virulence backgrounds, which will serve as a valuable reference for future studies. PMID:21478357

2011-04-08

452

An integrated genome research network for studying the genetics of alcohol addiction  

British Library Electronic Table of Contents (United Kingdom)

Abstract Alcohol drinking is highly prevalent in many cultures and contributes to the global burden of disease. In fact, it was shown that alcohol constitutes 3.2% of all worldwide deaths in the year 2006 and is linked to more than 60 diseases, including cancers, cardiovascular diseases, liver cirrhosis, neuropsychiatric disorders, injuries and foetal alcohol syndrome. Alcoholism, which has been proven to have a high genetic load, is one potentially fatal consequence of chronic heavy alcohol consumption, and may be regarded as one of the most prevalent neuropsychiatric diseases afflicting our society today. The aim of the integrated genome research network -Genetics of Alcohol Addiction--which is a German inter-/trans-disciplinary life science consortium consisting of molecular biologists,...

2010-01-01

453

The normal developmental regulation of a cloned sgs3 'glue' gene chromosomally integrated in Drosophila melanogaster by P element transformation.  

UK PubMed Central (United Kingdom)

A 7-kb genomic segment containing the coding sequence for the Drosophila melanogaster Formosa variant of salivary gland secretion protein 3 (sgs3) has been inserted into the snw y, bw, st strain of...Full Text Available

1983-01-01

454

The Complete Genome Sequence of Yersinia pseudotuberculosis IP31758, the Causative Agent of Far East Scarlet-Like Fever  

UK PubMed Central (United Kingdom)

The first reported Far East scarlet-like fever (FESLF) epidemic swept the Pacific coastal region of Russia in the late 1950s. Symptoms of the severe infection included erythematous skin rash and desquamation,...Full Text Available

2007-08-01

455

The Acidic Domain of Hepatitis C Virus NS4A Contributes to RNA Replication and Virus Particle Assembly?  

UK PubMed Central (United Kingdom)

Hepatitis C virus NS3-4A is a membrane-bound enzyme complex that exhibits serine protease, RNA helicase, and RNA-stimulated ATPase activities. This enzyme complex is essential for viral genome replication...Full Text Available

2011-02-01

456

Structural Chemistry of Human SET Domain Protein Methyltransferases  

Science.gov (United States)

There are about fifty SET domain protein methyltransferases (PMTs) in the human genome, that transfer a methyl group from S-adenosyl-L-methionine (SAM) to substrate lysines on histone tails or other peptides. A number of structures in complex with cofactor, substrate, or inhibitors revealed the mechanisms of substrate recognition, methylation state specificity, and chemical inhibition. Based on these structures, we review the structural chemistry of SET domain PMTs, and propose general concepts towards the development of selective inhibitors.

2011-08-22

457

Sequencing and Comparative Genomic Analysis of pK29, a 269-Kilobase Conjugative Plasmid Encoding CMY-8 and CTX-M-3 ?-Lactamases in Klebsiella pneumoniae?  

UK PubMed Central (United Kingdom)

A 269-kilobase conjugative plasmid, pK29, from a Klebsiella pneumoniae strain was sequenced. The plasmid harbors multiple antimicrobial resistance genes, including those encoding CMY-8...Full Text Available

2007-08-01

458

Sequence analysis of two alleles reveals that intra-and intergenic recombination played a role in the evolution of the radish fertility restorer (Rfo)  

UK PubMed Central (United Kingdom)

BackgroundLand plant genomes contain multiple members of a eukaryote-specific gene family encoding proteins with pentatricopeptide repeat (PPR) motifs. Some PPR proteins were shown...Full Text Available

459

Production of Infectious Genotype 1b Virus Particles in Cell Culture and Impairment by Replication Enhancing Mutations  

Science.gov (United States)

With the advent of subgenomic hepatitis C virus (HCV) replicons, studies of the intracellular steps of the viral replication cycle became possible. These RNAs are capable of self-amplification in cultured human hepatoma cells, but save for the genotype 2a isolate JFH-1, efficient replication of these HCV RNAs requires replication enhancing mutations (REMs), previously also called cell culture adaptive mutations. These mutations cluster primarily in the central region of non-structural protein 5A (NS5A), but may also reside in the NS3 helicase domain or at a distinct position in NS4B. Most efficient replication has been achieved by combining REMs residing in NS3 with distinct REMs located in NS4B or NS5A. However, in spite of efficient replication of HCV genomes containing such mutations, they do not support production of infectious virus particles. By using the genotype 1b isolate Con1, in this study we show that REMs interfere with HCV assembly. Strongest ...

2009-06-12

460

Plant Sulphur Nutrition  

Environmental Research Database

DescriptionThe recent sequencing of the complete genomes of several streptomycete species revealed the presence of a large number of cryptic' secondary metabolic gene clusters, and led to the realisation that these organisms have the ability to produce many more natural products than had previously been recognised. One of the aims of our work is to identify the physiological signals and regulatory mechanisms responsible for the activation of these 'cryptic' pathways, thus unleashing the full biosynthetic p [continued...

2010-01-31

461

Ordered Cloned DNA Map of the Genome of Vibrio cholerae 569B and Localization of Genetic Markers  

UK PubMed Central (United Kingdom)

By using a low-resolution macrorestriction map as the foundation (R. Majumder et al., J. Bacteriol. 176:1105–1112, 1996), an ordered cloned DNA map of the 3.2-Mb chromosome of the hypertoxinogenic...Full Text Available

1998-02-01

462

Meta-Analysis for Genome-Wide Association Study Identifies Multiple Variants at the BIN1 Locus Associated with Late-Onset Alzheimer's Disease  

UK PubMed Central (United Kingdom)

Recent GWAS studies focused on uncovering novel genetic loci related to AD have revealed associations with variants near CLU, CR1, PICALM and BIN1....Full Text Available

463

Isolation, sequence, and expression in Escherichia coli of an unusual thioredoxin gene from the cyanobacterium Anabaena sp. strain PCC 7120.  

UK PubMed Central (United Kingdom)

Two sequences with homology to a thioredoxin oligonucleotide probe were detected by Southern blot analysis of Anabaena sp. strain PCC 7120 genomic DNA. One of the sequences was shown to code for a protein...Full Text Available

1989-01-01

464

Investigation of genomic instability by assay of DNA fingerprint from the offspring of male mice exposed to chronic low-level #gamma#-radiation  

International Nuclear Information System (INIS)

By polymerase chain reaction with arbitrary primer (AP-PCR), the possibility of transmission of genome instability to somatic cells of the offspring (F_1 generation) from male parents of mice exposed to chronic low-dose #gamma#-radiation was studied. Male mice 15 days after exposure to 10-50 cGy were mated with unirradiated females. Biopsies were taken from tale tips of two month-old mice progeny for DNA separation. Primer in the AP-PCR was 20-mer oligonucleotide flanking the micro-satellite locus Atplb2 on chromosome 11 of the mouse. Comparative analysis of individual fingerprints of AP-PCR products on DNA-templates from the offspring of irradiated and unirradiated male mice revealed an increased variability of micro-satellite-associated sequences in the genome of the offspring of males exposed to 25 and 50 cGy. DNA-fingerprints of the offspring of male mice exposed to chronic irradiation doses 10 and 25 cGy. 15 days before fertilization (at ...

2000-11-20

465

Intragenic rearrangements of a mycoreovirus induced by the multifunctional protein p29 encoded by the prototypic hypovirus CHV1-EP713  

UK PubMed Central (United Kingdom)

Mycoreovirus 1 (MyRV1), a member of the Reoviridae family possessing a genome consisting of 11 dsRNA segments (S1–S11), and the prototype hypovirus (CHV1-EP713)...Full Text Available

2008-12-01

466

Human thrombomodulin gene is intron depleted: nucleic acid sequences of the cDNA and gene predict protein structure and suggest sites of regulatory control.  

UK PubMed Central (United Kingdom)

We have isolated a human thrombomodulin cDNA, and a human genomic clone containing the putative promoter domain, as well as the translated and untranslated regions of the endothelial cell receptor....Full Text Available

1987-09-01

467

Haplotyping and copy number estimation of the highly polymorphic human beta-defensin locus on 8p23 by 454 amplicon sequencing  

UK PubMed Central (United Kingdom)

BackgroundThe beta-defensin gene cluster (DEFB) at chromosome 8p23.1 is one of the most copy number (CN) variable regions of the human genome. Whereas individual DEFB CNs have been...Full Text Available

468

Global analysis of estrogen receptor beta binding to breast cancer cell genome reveals an extensive interplay with estrogen receptor alpha for target gene regulation  

UK PubMed Central (United Kingdom)

BackgroundEstrogen receptors alpha (ERα) and beta (ERβ) are transcription factors (TFs) that mediate estrogen signaling and define the hormone-responsive phenotype...Full Text Available

469

Genomic sequence for human prointerleukin 1 beta: possible evolution from a reverse transcribed prointerleukin 1 alpha gene.  

UK PubMed Central (United Kingdom)

We have isolated the human prointerleukin 1 (proIL-1) beta gene from leukocyte and fetal liver libraries. The nucleotide sequence and its gene organization reveals that the proIL-1 beta gene is composed...Full Text Available

1986-10-24

470

Genome-wide analysis reveals rapid and dynamic changes in miRNA and siRNA sequence and expression during ovule and fiber development in allotetraploid cotton (Gossypium hirsutum L.)  

UK PubMed Central (United Kingdom)

BackgroundCotton fiber development undergoes rapid and dynamic changes in a single cell type, from fiber initiation, elongation, primary and secondary wall biosynthesis, to fiber...Full Text Available

2009-01-01

471

Genome-wide analysis of N1-methyl-adenosine modification in human tRNAs  

UK PubMed Central (United Kingdom)

The N1-methyl-Adenosine (m1A58) modification at the conserved nucleotide 58 in the TΨC loop is present in most eukaryotic tRNAs. In yeast, m1A58 modification...Full Text Available

2010-07-01

472

Genome analysis of F. nucleatum sub spp vincentii and its comparison with the genome of F. nucleatum ATCC 25586.  

Science.gov (United States)

We present the draft genome sequence and its analysis for Fusobacterium nucleatum sub spp. vincentii (FNV), and compare that genome with F. nucleatum ATCC 25586 (FN). A total of 441 FNV open reading frames (ORFs) with no orthologs in FN have been identified. Of these, 118 ORFs have no known function and are unique to FNV, whereas 323 ORFs have functional orthologs in other organisms. In addition to the excretion of butyrate, H2S and ammonia-like FN, FNV has the additional capability to excrete lactate and aminobutyrate. Unlike FN, FNV is likely to incorporate galactopyranose, galacturonate, and sialic acid into its O-antigen. It appears to transport ferrous iron by an anaerobic ferrous transporter. Genes for eukaryotic type serine/threonine kinase and phosphatase, transpeptidase E-transglycosylase Pbp1A are found in FNV but not in FN. Unique ABC transporters, cryptic phages, and three types of restriction-modification systems have been ...

2003-06-01

473

Genome Sequence of a Lancefield Group C Streptococcus zooepidemicus Strain Causing Epidemic Nephritis: New Information about an Old Disease  

UK PubMed Central (United Kingdom)

Outbreaks of disease attributable to human error or natural causes can provide unique opportunities to gain new information about host-pathogen interactions and new leads for pathogenesis research....Full Text Available

474

Explore - The Lab - Australian Broadcasting Corporation's Gateway to Science  

Wastenet

...Explore - The Lab - Australian Broadcasting Corporation's Gateway to Science Radio TV Shop News Sport Local Children Science Environment more Topics help Science Home News in Science Features Explore TV & Radio Dr Karl Play Podcasts DNA - The discovery of the double helix structure of DNA completely changed biology and opened up the new field of genetics. The 'backbone of life' has given us the human genome, stem cell research, ...

475

Evolution of a cluster of innate immune genes (?-defensins) along the ancestral lines of chicken and zebra finch  

UK PubMed Central (United Kingdom)

BackgroundAvian β-defensins (AvBDs) represent a group of innate immune genes with broad antimicrobial activity. Within the chicken genome, previous work identified 14 AvBDs...Full Text Available

476

Environmentally-Induced Malignancies: An In Vivo Model to Evaluate the Health Impact of Chemicals in Mixed Waste  

Energy Technology Data Exchange (ETDEWEB)

Occupational and environmental exposure to organic ligands, solvents, fuel hydrocarbons, and polychlorinated biphenyls are linked with increased risk of hematologic malignancies. DOE facilities and waste sites in the U.S. are contaminated with mixtures of potentially hazardous chemicals such as metals, organic ligands, solvents, fuel hydrocarbons, polychlorinated biphenyls and radioactive isotopes. A major goal of this project was to establish linkage between chemical/radiation exposure and induction of genomic damage in target populations with the capability to undergo transformation.

2001-05-04

477

Dramatic Effects of 2-Bromo-5,6-Dichloro-1-?-d-Ribofuranosyl Benzimidazole Riboside on the Genome Structure, Packaging, and Egress of Guinea Pig Cytomegalovirus  

UK PubMed Central (United Kingdom)

The halogenated benzimidazoles BDCRB (2-bromo-5,6-dichloro-1-β-d-riborfuranosyl benzimidazole riboside) and TCRB (2,5,6-trichloro-1-β-d-riborfuranosyl benzimidazole...Full Text Available

2004-02-01

478

Differential decay of parent-of-origin-specific genomic sharing in cystic fibrosis-affected sib pairs maps a paternally imprinted locus to 7q34  

UK PubMed Central (United Kingdom)

Cystic fibrosis (CF) is a monogenic disease characterized by a high variability of disease severity and outcome that points to the role of environmental factors and modulating genes that shape the course...Full Text Available

2010-05-01

479

Deep short-read sequencing of chromosome 17 from the mouse strains A/J and CAST/Ei identifies significant germline variation and candidate genes that regulate liver triglyceride levels  

UK PubMed Central (United Kingdom)

Genome sequences are essential tools for comparative and mutational analyses. Here we present the short read sequence of mouse chromosome 17 from the Mus musculus domesticus derived...Full Text Available

2009-01-01

480

DNA rearrangements from #gamma#-irradiated normal human fibroblasts preferentially occur in transcribed regions of the genome  

International Nuclear Information System (INIS)

Full text: DNA rearrangement events leading to chromosomal aberrations are central to ionizing radiation-induced cell death. Although DNA double-strand breaks are probably the lesion that initiates formation of chromosomal aberrations, little is understood about the molecular mechanisms that generate and modulate DNA rearrangement. Examination of the sequences that flank sites of DNA rearrangement may provide information regarding the processes and enzymes involved in rearrangement events. Accordingly, we developed a method using inverse PCR that allows the detection and sequencing of putative radiation-induced DNA rearrangements in defined regions of the human genome. The method can detect single copies of a rearrangement event that has occurred in a particular region of the genome and, therefore, DNA rearrangement detection does not require survival and continued multiplication of the affected cell. Ionizing radiation-induced DNA ...

2003-08-17

481

Computational identification of developmental enhancers:conservation and function of transcription factor binding-site clustersin drosophila melanogaster and drosophila psedoobscura  

Energy Technology Data Exchange (ETDEWEB)

Background The identification of sequences that control transcription in metazoans is a major goal of genome analysis. In a previous study, we demonstrated that searching for clusters of predicted transcription factor binding sites could discover active regulatory sequences, and identified 37 regions of the Drosophila melanogaster genome with high densities of predicted binding sites for five transcription factors involved in anterior-posterior embryonic patterning. Nine of these clusters overlapped known enhancers. Here, we report the results of in vivo functional analysis of 27 remaining clusters. Results We generated transgenic flies carrying each cluster attached to a basal promoter and reporter gene, and assayed embryos for reporter gene expression. Six clusters are enhancers of adjacent genes: giant, fushi tarazu, odd-skipped, nubbin, squeeze and pdm2; three drive expression in patterns unrelated to those of neighboring genes; the ...

2004-08-06

482

Comparative transcriptional pathway bioinformatic analysis of dietary restriction, Sir2, p53 and resveratrol life span extension in Drosophila  

UK PubMed Central (United Kingdom)

A multiple comparison approach using whole genome transcriptional arrays was used to identify genes and pathways involved in calorie restriction/dietary restriction (DR) life span extension in Drosophila....Full Text Available

2011-03-15

483

Cell-cycle-related biosynthesis. [Sarkosyl, neocarzinostatin, adriamycin  

Science.gov (United States)

The state of chromatin during the cell cycle was examined using synchronized cultures of CHO hamster cells. Results support Mazia's dynamic chromosome cycle model and indicate that DNA-interactive chemotherapeutic agents elicit different types of kinetic responses in treated cells, suggesting a degree of specificity of interaction between various alkylating and intercalating agents and the genome. Effects of sarkosyl crystals, heparin, and chemotherapeutic agents, neocarzinostatin and adriamycin, on chromation are discussed. (HLW)

1976-01-01

484

Biochemical and Structural Characterization of the Secreted Chorismate Mutase (Rv1885c) from Mycobacterium tuberculosis H37Rv: an *AroQ Enzyme Not Regulated by the Aromatic Amino Acids  

UK PubMed Central (United Kingdom)

The gene Rv1885c from the genome of Mycobacterium tuberculosis H37Rv encodes a monofunctional and secreted chorismate mutase (*MtCM) with a 33-amino-acid...Full Text Available

2006-12-01

485

Analysis of the transcript encoding the latent Epstein-Barr virus nuclear antigen I: a potentially polycistronic message generated by long-range splicing of several exons.  

UK PubMed Central (United Kingdom)

The Epstein-Barr virus nuclear antigen (EBNA I) present in latently infected cells is encoded in a 2-kilobase exon contained in the BamHI K viral genomic fragment. This exon is, however, found within...Full Text Available

1985-12-01

486

Analysis of the 10q11 Cancer Risk Locus Implicates MSMB and NCOA4 in Human Prostate Tumorigenesis  

UK PubMed Central (United Kingdom)

Genome-wide association studies (GWAS) have established a variant, rs10993994, on chromosome 10q11 as being associated with prostate cancer risk. Since the variant is located outside of a protein-coding...Full Text Available

2010-11-01

487

A Nonparametric Mean-Variance Smoothing Method to Assess Arabidopsis Cold Stress Transcriptional Regulator CBF2 Overexpression Microarray Data  

UK PubMed Central (United Kingdom)

Microarray is a powerful tool for genome-wide gene expression analysis. In microarray expression data, often mean and variance have certain relationships. We present a non-parametric mean-variance smoothing...Full Text Available

488

Local chromatin structure of heterochromatin regulates repeatedDNA stability, nucleolus structure, and genome integrity  

Energy Technology Data Exchange (ETDEWEB)

Heterochromatin constitutes a significant portion of the genome in higher eukaryotes; approximately 30% in Drosophila and human. Heterochromatin contains a high repeat DNA content and a low density of protein-encoding genes. In contrast, euchromatin is composed mostly of unique sequences and contains the majority of single-copy genes. Genetic and cytological studies demonstrated that heterochromatin exhibits regulatory roles in chromosome organization, centromere function and telomere protection. As an epigenetically regulated structure, heterochromatin formation is not defined by any DNA sequence consensus. Heterochromatin is characterized by its association with nucleosomes containing methylated-lysine 9 of histone H3 (H3K9me), heterochromatin protein 1 (HP1) that binds H3K9me, and Su(var)3-9, which methylates H3K9 and binds HP1. Heterochromatin formation and functions are influenced by HP1, Su(var)3-9, and the RNA interference (RNAi) pathway. My thesis project ...

2007-05-05

489

WHO wants more use of irradiated food, calls for education programs  

International Nuclear Information System (INIS)

Short note. The World Health Organization (WHO) has taken aim at critics of irradiated food, claiming that the process has the potential to reduce the incidence of foodborne diseases such as salmonellosis, to cut postharvest food losses and to provide a wider variety of foods for consumers. 'The unwarranted rejection of this process, often based on lack of understanding of what food irradiation entails, may hamper its use in those countries which may benefit most', Dr. Jean-Paul Jardel, WHO's assistant director-general, argued following a recent international conference on the subject. Critics, including Canadians, has opposed food irradiation for years, claiming that more needs to be known about its effects. WHO said the 'vast majority' of the 54 national delegations at the conference supported use of the technology on foods ranging from grain and potatoes to poultry, tropical fruit and strawberries. WHO wants governments to educate the public ...

1989-02-01

490

Stationary fuel cell systems - market introduction. Conference; Stationaere Brennstoffzellenanlagen - Markteinfuehrung. Tagung  

Energy Technology Data Exchange (ETDEWEB)

The conference reviewed the state of the art of stationary fuel cell systems, concepts, and the next steps to be taken. Fuel cell systems of several hundred kW have been designed and constructed already. Systems for domestic power supply are in the range of several kW. [German] Die in den letzten zehn Jahren gewonnenen Erfahrungen mit den ersten Pilotanlagen sind eine wichtige und unentbehrliche Hilfe den Weg in den Markt fuer die Brennstoffzelle zu ebnen. Der vorliegende Tagungsband soll diese Erfahrungen fuer die stationaer eingesetzten Brennstoffzellen zusammenfassen und ein aktuelles Bild ueber die daraus gewonnenen Konzepte und Vorstellungen fuer die naechsten Schritte aufzeigen. Bei Energieversorgern sind hier Leistungsgroessen von bis zu mehreren 100 kW eingesetzt worden. Der Leistungsbereich, der fuer die Aufgaben der Hausenergieversorgung typisch ist, befindet sich demgegenueber im Bereich einiger kW. (orig.)

2001-07-01

491

Small-satellite technology and applications III  

Energy Technology Data Exchange (ETDEWEB)

This third conference on small-satellite applications has combined a number of significant and timely presentations on the status, in the US and on the international front, of this emerging industry. Presentations by all of the major Department of Defense activities in this field, including an overview of the ARPA CAMEO multispectral remote sensing satellite program, space activities at the Air Force Phillips Laboratory, and a space systems capabilities overview of the Naval Research Laboratory, are complemented by presentations from several international activities on their accomplishments and progress in the development of remote sensing satellite programs. For example: Spar Aerospace of Canada presented an overview of the progress they have made in establishing a space program through the use of small satellites, and the University of Surrey and Spar Aerospace provided an overview of the application of image compression schemes to imagery obtained from their ...

1993-01-01

492

Rice RING protein OsBBI1 with E3 ligase activity confers broad-spectrum resistance against Magnaporthe oryzae by modifying the cell wall defence  

British Library Electronic Table of Contents (United Kingdom)

Emerging evidence suggests that E3 ligases play critical roles in diverse biological processes, including innate immune responses in plants. However, the mechanism of the E3 ligase involvement in plant innate immunity is unclear. We report that a rice gene, OsBBI1, encoding a RING finger protein with E3 ligase activity, mediates broad-spectrum disease resistance. The expression of OsBBI1 was induced by rice blast fungus Magnaporthe oryzae, as well as chemical inducers, benzothiadiazole and salicylic acid. Biochemical analysis revealed that OsBBI1 protein possesses E3 ubiquitin ligase activity in vitro. Genetic analysis revealed that the loss of OsBBI1 function in a Tos17-insertion line increased susceptibility, while the overexpression of OsBBI1 in transgenic plants conferred enhanced resi...

2011-01-01

493

Proceedings of the 2. international conference on accelerator-driven transmutation technologies and applications  

International Nuclear Information System (INIS)

Technical developments in the construction of high power accelerators have created new research activities on accelerator-driven transmutation technologies (ADTT) with main applications for energy production and nuclear waste transmutation. The on-going research was reported and discussed at the conference. The studies of energy production based on ADTT indicate possible important advantages compared to the present nuclear power reactors. Natural Uranium or Thorium is burned in a subcritical reactor with or without simultaneous incineration and transmutation of nuclear waste. High level radioactive wastes and weapons Plutonium constitute an environmental and proliferation problem. Studies were reported on the possibilities to use ADTT to considerably shorten the life-time and reduce the amount of long-lived radioactive waste in order to decrease the volumes needed for long-term geologic deposition. A panel discussed the ADTT impact on nuclear waste disposal, ...

1996-06-03

494

Historical on the Norm Related to the CO{sub 2} Emission Integrated in the Protocol of Kyoto; Historico sobre la Normativa Relacionada con las Emisiones de CO{sub 2} Integrado en el Protocolo de Kyoto  

Energy Technology Data Exchange (ETDEWEB)

The United Nations Framework Convention on Climate Change (UNFCCC) was approved in 1992 to respond to the worl-wide concern about the warming of the planet. The primary target was the stabilization of the concentration of greenhouse gases in the atmosphere, in an attempt to reduce to the minimum the degradation of the environment caused by humans. By virtue of the Convention, the Parts2 are committed to reach their objectives in the reduction of the emissions. A Conference of the Parts was stablished to promote the effective application of the Convention. The third Conference of the Parts, celebrated in Kyoto (Japan, 1997) approved, by consensus, the denominated Kyoto Protocol, in which 39 developed countries and countries with economies in transition were committed to reduce their emissions of greenhouse gases between years 2008 and 2012 in a 5.2 global percent with respect to the 1990 levels. Three {sup f}lexibility mechanisms{sup w}ere ...

2006-07-01

495

Getting America Ready for Japanese Science and Technology.  

Science.gov (United States)

The proceedings of a conference on the development of language capabilities to prepare United States scientists to share in scientific and technological development with Japan include these papers: "Are Japanese Language Programs Reaching Scientists and Engineers?"; "Japanese Language Study for Engineers: High Tech Perspectives"; "Applied Japanese Studies for Science and Engineering at American Universities"; "Training and Certifying Japanese Technical Translators"; "Designing Effective Language Teaching for Professionals"; "Problems in Teaching Technical Japanese"; "Commentary" A Cautious and Deliberate Strategy Is Needed"; "Establishing a Japanese High-Technology Information Company in the United States"; "The Problems of Operating a Technical Translation Company in Japan";"The Japan Information Center of Science and Technology"; "A National Agenda for Japanese Language Training"; "National Language Policies and the 99th Congress"; "Machine Translations: ...

1985-05-15

496

DC-DC converter for hybrid vehicles; Shasaiyo DC-DC converter  

Energy Technology Data Exchange (ETDEWEB)

In response to the decisions adopted at the Third Session of the Conference of the Parties to the United Nations Framework Convention on Climate Change (Kyoto conference for the prevention of global warming) of 1997, hybrid vehicles, electric vehicles, and the like are being announced of their completion or placed on the market one after another as low pollution vehicles with CO2 emission to cause global warming reduced. Fuji Electric Co., Ltd., is engaged in the development of a DC-DC converter for hybrid vehicles in cooperation with Nissan Motor Co., Ltd. The product is characterized in (1) that it is small in size and light in weight because a step-down converter and an emergency step-up converter are integrated; (2) that it enjoys a high efficiency rate of 89%; (3) that its service life is long thanks to its design free of aluminum electrolytic capacitors; and (4) that it is provided with various reliability improving features, such as ...

2000-01-10

497

Analysis of forward mutations induced by N-methyl-N'-nitro-N-nitrosoguanidine in the bacteriophage P22 mnt repressor gene  

Energy Technology Data Exchange (ETDEWEB)

We describe the isolation and genetic characterization of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced mutations in the phage P22 mnt repressor gene cloned in plasmid pBR322. Mutations in the mnt repressor gene or its operator on this plasmid, pPY98, confer a tetracycline resistance phenotype, whereas the wild-type plasmid confers tetracycline sensitivity. Cells carrying pPY98 were briefly exposed to MNNG to give 20 to 40% survival and a 50- to 100-fold increase in tetracycline-resistant cells. DNA sequence analysis showed that 29 to 30 MNNG-induced mutations were GC-to-AT transitions and one was an AT-to-GC transition. About 80% of the mutations are in three hotspots. This mutation spectrum is consistent with the proposed mechanism of mutagenic action of MNNG, which involves mispairing of an alkylated base, O/sup 6/-methylguanine. The mnt gene may be a useful target for determining mutagenic specificity at the nucleotide level ...

1986-04-01

498

Trajectory of virtual, bound and resonant Efimov states  

International Nuclear Information System (INIS)

The pole trajectory of Efimov states for a three-body ??? system with ?? unbound and ?? bound is calculated using a zero-range Dirac-? potential. It is shown that a three-body bound state turns into a virtual one by increasing the ?? binding energy. This result is consistent with previous results for three equal mass particles. The present approach considers the n-n-18C halo nucleus. However, the results have good perspective to be tested and applied in ultracold atomic systems, where one can realize such three-body configuration with tunable two-body interaction. Presented at the 20th Few-Body Conference, Pisa, Italy, 10-14 September 2007. (author)

499

Confrontation between stellar pulsation and evolution; Proceedings of the Conference (ASP Series, Vol. 11), Bologna, Italy, May 28-31, 1990  

International Nuclear Information System (INIS)

Attention is given to the folowing topics: population I and II variable stars; LP variables, the sun, and mass determination; and predegenerate and degenerate variables. Particular papers are presented on alternative evolutionary approaches to the absolute magnitude of the RR Lyrae variables; the evolution of the Cepheid stars; nonradial pulsations in rapidly rotating Delta Scuti stars; dynamical models of dust shells around Mira variables; and pulsations of central stars of planetary nebulae.

1990-05-28

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BNES materials conference a status review of alloy 800  

International Nuclear Information System (INIS)

Existing applications of Alloy 800 are summarized, with particular reference to its use in various types of reactor. The need for a co-ordinated research and development programme is stressed, and the variables to be explored are outlined. The papers relating to the problem of corrosion and cracking in water and steam are considered. the strength and ductility of Alloy 800 is considered. Finally, sections of the summary deal with the use of Alloy 800 for (a) sodium cooled fast reactor boiler tubes; (b) the high temperature gas cooled reactor; and (c) PWR steam generator tubes. (U.K.).