WorldWideScience
1

A Preference for a Sexual Signal Keeps Females Safe  

UK PubMed Central (United Kingdom)

Predation is generally thought to constrain sexual selection by female choice and limit the evolution of conspicuous sexual signals. Under high predation risk, females usually become less choosy, because...Full Text Available

2

Perceptions of tobacco health warnings in China compared with picture and text-only health warnings from other countries: an experimental study  

UK PubMed Central (United Kingdom)

ObjectiveTo assess the perceived effectiveness of cigarette health warnings in China, compared with picture and text-only warnings from other countries.Method1169...Full Text Available

2010-10-01

3

Better machinery monitoring  

Energy Technology Data Exchange (ETDEWEB)

This paper discusses how specialized techniques for machine condition monitoring can help to eliminate false alarms and undetected faults, leading to a truly cost effective predictive maintenance program. It is vital to base the monitoring system on the parameter which will give the most useful information about potential faults and breakdowns. This parameter is generally agreed to be vibration. While oil debris analysis and variations in temperature, geometry and machine speed can all give advance warning of faults, no other parameter can reveal as wide a range of fault types as vibration. The vibration transducers job is to accurately and faithfully convert the vibration into an electric signal for assessment. If this part of the system is weak, reliability will be badly affected. Data integrity is crucial.

1990-07-01

4

DEVELOPMENT OF THE PILOT WARNING INSTRUMENT ...  

Science.gov (United States)

... multivibrators and amplifiers arranged to operate as described above. ... The first of the multivibrators is triggered by the trailing edge of the ...

1962-02-01

5

SPACE FLIGHT 1999 - NASA  

Science.gov (United States)

Mission losses were incurred by an early warning satellite and a Milstar-2 communications satellite when their launch vehicles malfunctioned, the first, ...

6

DC-DC converter for hybrid vehicles; Shasaiyo DC-DC converter  

Energy Technology Data Exchange (ETDEWEB)

In response to the decisions adopted at the Third Session of the Conference of the Parties to the United Nations Framework Convention on Climate Change (Kyoto conference for the prevention of global warming) of 1997, hybrid vehicles, electric vehicles, and the like are being announced of their completion or placed on the market one after another as low pollution vehicles with CO2 emission to cause global warming reduced. Fuji Electric Co., Ltd., is engaged in the development of a DC-DC converter for hybrid vehicles in cooperation with Nissan Motor Co., Ltd. The product is characterized in (1) that it is small in size and light in weight because a step-down converter and an emergency step-up converter are integrated; (2) that it enjoys a high efficiency rate of 89%; (3) that its service life is long thanks to its design free of aluminum electrolytic capacitors; and (4) that it is provided with various reliability improving features, such as protective systems and ...

2000-01-10

7

Application of a finite element method to leak before break (LBB) of a heat exchanger  

International Nuclear Information System (INIS)

The leak before break (LBB) concept is difficult to apply to a structure with a thin tube that is immersed in a water environment. A heat exchanger in a nuclear power plant is such a structure. The present paper addresses an application of the LBB concept to a heat exchanger in a nuclear power plant. The minimum leaked coolant amount containing the radioactive material which can activate the radiation detector device installed near the heat exchanger is assumed. The postulated initial flaw size that cannot grow to the critical flaw size within the time period to activate the radiation detector is justified. In this case, the radiation detector can activate the warning signal caused by coolant leakage from initially postulated flaws of the heat exchanger. The nuclear plant can safely shutdown when this occurs. Since the postulated initial flaw size can not grow to the critical flaw size, the structural integrity of the heat exchanger is not ...

2003-08-17

8

Dual Energy and Low kVp CT in the Abdomen  

UK PubMed Central (United Kingdom)

Low kVp settings provide high conspicuity of contrast materials at CT but may result in high image noise, particularly in larger patients. Material decomposition at dual energy CT can differentiate...Full Text Available

2009-07-01

9

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Wastenet

...Publications Consultations Application forms Vacancies Contact us About us Air Climate change Flooding Live flood warnings Flood map How to use it About the ...map View the map FAQs Contact us & Feedback Flooding: who does what? Flood warning - what we do Floodline Warnings Direct Flood ...risk Being prepared FAQs Floodline kids Flooding publications External links Business & Flood Risk Seminar Contact us Land Planning Radioactive substances Waste Water ... You are here: Home Page Flooding Flood map View the map View the map: terms and conditions Important information about ...

10

Warning Signs and Risk Factors  

Medline Plus

[music] Narrator: New treatments can limit the disability caused by a stroke, but you need to know the signs and act in time. Here are the signs to ...

11

United States Space Activities - NASA  

Science.gov (United States)

Mission losses were incurred by an early warning satellite and a Milstar-2 communications satellite when their launch vehicles malfunctioned, the first, ...

12

The Stryker Brigade Combat Team. Rethinking Strategic ...  

Science.gov (United States)

... For short-warning crises in other regions, Marine Expeditionary Units, the 82nd Airborne Division, Special Operations Forces, and Air Force/Navy ...

13

Proposed Network Security Policy for Integrated Tactical ...  

Science.gov (United States)

... MTR 93B0000095 Proposed Network Security Policy for Integrated Tactical Warning ... Proposed Network security Policy for Integrated Tactical ...

1993-09-01

14

Panel warns of a crisis in american Physics  

CERN Multimedia

"Physics in America is at a crossroads and in crisis, just as humanity stands on the verge of great discoveries about the nature of matter and the universe, a panel from the National Academy of sciences concludes in a new report."

2006-01-01

15

Lightning Detection for an Air Force Automated Observation ...  

Science.gov (United States)

... of six lightning warning systems was carried out in 1979 as a result of lightning-induced premature explosions in open-pit mining operations. ...

1988-06-08

16

Late Life-Threatening Hemorrhage after Percutaneous Tracheostomy  

UK PubMed Central (United Kingdom)

Purpose. Formation of a tracheoinnominate artery fistula (TIF) and consecutive hemorrhage is a rare and life-threatening complication with high mortality. Warning symptoms can...Full Text Available

2011-01-01

17

Fast Flux Test Facility performance monitoring management information, April 1988  

Energy Technology Data Exchange (ETDEWEB)

The purpose of this report is to provide management with performance data on key performance indicators selected from the FFTF Early Warning System performance indicators.

1988-05-01

18

Experts worry US may lose leadership in particle physics  

CERN Multimedia

"Physics in the United States is in a crisis that the country may lose the leadership in basic particle research in coming years, a report of the National Research Council warned." (1 page)

2006-01-01

19

Smog alarm. Five functions of special emergency measures. Smogalarm. Fuenf Funktionen der unmittelbaren Gefahrenabwehr im Umweltschutz  

Energy Technology Data Exchange (ETDEWEB)

Most environmental policies provide for special emergency measures to be taken during phases of high pollution, such as smog alarm regulations. These measures serve several purposes and can have various impacts. First of all, they act as a warning to those parts of the population immediately threatened by health hazards (Warnfunktion). They may be directed at short-term pollution reduction via pollution abatement measures proscribed during smog alarm situations (unmittelbare Steuerungsfunktion). In addition, the announcement of emergency measures may signal that pollution levels in general have been too high, indicating that the environmental policies normally pursued do not sufficiently or effectively protect human beings and the environment from harm (Signalfunktion). Emergency measures often contain special regulations obliging industrial polluters to switch to costly, less polluting production processes, or to stop production altogether. ...

1985-01-01

20

Assessment of leak detection capability of Candu 6 annulus gas system using moisture injection tests  

Energy Technology Data Exchange (ETDEWEB)

The Candu 6 reactor assembly consists of an array of 380 pressure tubes, which are installed horizontally in a large cylindrical vessel, the Calandria, containing the low pressure heavy water moderator. The pressure tube is located inside calandria tube and the annulus between these tubes, which forms a closed loop with CO{sub 2} gas recirculating, is called the Annulus Gas System (AGS). It is designed to give an alarm to the operator even for a small pressure tube leak by a very sensitive dew point meter so that he can take a preventive action for the pressure tbe rupture incident. To judge whether the operator action time is enough or not in the design of Wolsung 2, 3, and 4, the Leak Before Break (LBB) assessment is required for the analysis of the pressure tube failure accident. In order to provide the required data for the LBB assessment of Wolsung Units 2, 3, 4, a series of leak detection capability tests was performed by injecting controlled rates of heavy water vapour. The data ...

1998-10-01

21

Comparative Analysis of State Fish Consumption Advisories Targeting Sensitive Populations  

UK PubMed Central (United Kingdom)

ObjectiveFish consumption advisories are issued to warn the public of possible toxicological threats from consuming certain fish species. Although developing fetuses and children...Full Text Available

2008-12-01

22

30 CFR 75.1403-10 - Criteria-Haulage; general.  

Science.gov (United States)

...persons from danger of runaway haulage equipment. (f) An audible warning...within 300 feet of preceding haulage equipment, except trailing locomotives...provided for all rubber-tired haulage equipment where such equipment is...

2010-07-01

24

Distributed radiation protection console system  

International Nuclear Information System (INIS)

Radiation exposure control is one of the most important aspects in any nuclear facility . It encompasses continuous monitoring of the various areas of the facility to detect any increase in the radiation level and/or the air activity level beyond preset limits and alarm the O and M personnel working in these areas. Detection and measurement of radiation level and the air activity level is carried out by a number of monitors installed in the areas. These monitors include Area Gamma Monitors, Continuous Air Monitors, Pu-In-Air Monitors, Criticality Monitors etc. Traditionally, these measurements are displayed and recorded on a Central Radiation Protection Console(CRPC), which is located in the central control room of the facility. This methodology suffers from the shortcoming that any worker required to enter a work area will have to inquire about the radiation status of the area either from the CRPC or will get to know the same directly from the installed only after entering the area. ...

2004-02-01

25

The skin of Osedax (Siboglinidae, Annelida): An ultrastructural investigation of its epidermis  

British Library Electronic Table of Contents (United Kingdom)

The symbiotic polychaetes of the genus Osedax living on the bones of whale carcasses have become known as bone-eating worms. It is believed that whale bones are the source of nutrition for those gutless worms and that fatty acids are produced by their symbionts and transferred to the host. However, the symbionts are of the heterotrophic group Oceanospirillales and as such are not able to synthesize organic carbon de novo. Also, they are not housed in close contact to the bone material. We studied the ultrastructure of the integument overlying the symbiont housing trophosome in the ovisac region and the roots region and of the symbiont-free trunk region of Osedax to investigate the hosts possible contribution in feeding for the whole symbiosis. The epidermis differs conspicuously between th...

2010-01-01

26

Are the delay images necessary to evaIuate the liver metastatic lesions on mangafodipir trisodium enhanced liver MRI?: comparison with hepatocellular carcinomas  

Energy Technology Data Exchange (ETDEWEB)

To assess whether ring enhancements of liver metastases on Mn-DPDP enhanced, early MR images were well visualized on delayed images, as compared with those of hepatocellular carcinomas (HCC), and to investigate the detection accuracy and conspicuity of each tumor. Twenty patients with liver metastases and 15 with HCC were studied by Mn-DPDP enhanced, T1-weighted MR images. Peripheral ring enhancement and conspicuity were investigated. Differences in detection accuracy and frequency of ring enhancement in liver metastases and HCC were assessed. In liver metastases (n= 69), 44 cases (63.8%) without ring enhancement and 25 (36.2%) with were noted on early images. Sixteen cases (23.2%) without ring enhancement, 38 (55.1%) with ring enhancement similar to the early images, and 15 (21.7%) with prominent ring enhancement were noted on delayed images. In HCC (n=37), 36 cases (97.3%) without ring enhancement and 1 case (2.7%) with were noted on early ...

2004-09-01

27

Table of Contents  

British Library Electronic Table of Contents (United Kingdom)

Abstract Overall Numbers Small, But Study Finds SSRI Exposure, Autism Link Additional Drug Safety, Efficacy Data Needed for Pediatric Bipolar Disorder SGA Safety and Efficacy in Children and Adolescents Aripiprazole Safety and Tolerability for Irritability in Autism No Lisdexamfetamine Effect on Sleep Disturbances in Children With ADHD Sickle Cell Disease With Comorbid Depression Homeopathy in Psychiatry Manic Symptoms Induced by Marijuana in a Healthy Adolescent New Warnings Safety Labeling Changes

2011-01-01

28

Prevent Diabetes Problems: Keep Your Heart and Blood Vessels Healthy  

Science.gov (United States)

... mini-stroke," also called a TIA or a transient ischemic attack . If you have any of these warning signs, ... ur-uhl) (ar-TEE-ree-uhl) (dih-ZEEZ) transient ischemic attack (TRANZ-see-uhnt) (iss-KEE-mik) (uh-TAK) [ ...

29

China's water crisis  

Energy Technology Data Exchange (ETDEWEB)

After the devastating natural disasters that have hit China recently, another crisis is looming, Drought, pollution and heavy usage in the fast-developing megacities have resulted in a shortage of water. A huge construction effort is underway to divert water from the south to the north. But experts warn that it will not solve China's structural water problems.

2008-07-15

30

The Effect of Reference Signals in a Visual Vigilance Task.  

Science.gov (United States)

The effect of reference signals on performance in a visual vigilance task was studied under three conditions. Reference signals were presented on the same display as the real signals. In condition 1 (control), no reference signals were displayed. Sugbject...

1969-01-01

31

An immunohistochemical study in cases with usual and unusual clinicopathological findings of canine visceral leishmaniosis  

British Library Electronic Table of Contents (United Kingdom)

The present study describes pathologic findings and immunohistochemical diagnosis of canine visceral leishmaniasis (CVL) in 22 dogs who died naturally in the Aegean region of Turkey. At necropsy, lymphadenomegaly, hepatosplenomegaly, hepatic, and nephrosclerotic lesions were conspicuous. Histopathologically, chronic inflammatory reactions of the spleen, lymph nodes, bone marrow, liver, and skin were marked findings. Cytological and histological examinations showed macrophages loaded with Leishmania amastigotes in these organs. Immunohistochemistry revealed that immunolabeling of amastigotes and/or parasite antigen, especially in the lymph nodes, spleen, bone marrow, liver, and skin, and occasionally, in the kidneys, intestines and lungs. Our laboratory results showed that immunohistochemis...

2011-01-01

32

Complete convergence of message passing algorithms for some satisfiability problems  

CERN Document Server

Experimental results show that certain message passing algorithms, namely, Survey Propagation, are very effective in finding satisfying assignments for random satisfiable 3CNF formulas which are considered hard for other SAT heuristics. Unfortunately, rigorous understanding of this phenomena is still lacking. In this paper we make a modest step towards providing rigorous explanation for the effectiveness of message passing algorithms. We analyze the performance of Warning Propagation, a popular message passing algorithm that is simpler than Survey Propagation. We show that for 3CNF formulas drawn from a certain distribution over random satisfiable 3CNF formulas, commonly referred to as the planted-assignment distribution, running Warning Propagation in the standard way (run message passing until convergence, simplify the formula according to the resulting assignment, and satisfy the remaining subformula, if necessary, using a simple "off the ...

2008-01-01

36

DNA ENCODING MODIFIED SIGNAL PEPTIDE  

J-STORE (Japan)

Full Text Available

2005-01-11

39

[Fritz hauschild (1908-1974) and drug research in the 'German Democratic Republic' (GDR)].  

Science.gov (United States)

The chemist and pharmacologist Fritz Hauschild developed the sympathomimetic agent Pervitin (metamphetamin) in the 1930s. Not only because of the abuse of the stimulant during the Second World War ("pilot's chocolate") it is one of the most controversial substances in drug history. Nearly forgotten are Hauschild's contributions to build up the drug system in the GDR. Although he was a convinced communist, the skilful pharmacologist gave very early warning of the imminent lack of innovation in the GDR pharmaceutical industry. A letter which he addressed to the Minister of Health, Max Sefrin (born 1913), did not lack explicitness. PMID:15997840

2005-06-01

40

The Landscape of International Biosurveillance  

Energy Technology Data Exchange (ETDEWEB)

Event-based biosurveillance is a scientific discipline in which diverse streams of data, available from the Internet, are characterized prospectively to provide information on infectious disease events. Biosurveillance complements traditional public health surveillance to provide both early warning of infectious disease events as well as situational awareness. The Global Health Security Action Group (GHSAG) of the Global Health Security Initiative is developing a biosurveillance capability that integrates and leverages component systems from member nations. This work discusses these biosurveillance systems and identifies needed future studies.

2010-02-01

41

Telephone: it will never be the same  

Energy Technology Data Exchange (ETDEWEB)

A respected veteran among state utility regulators raises a sober warning that it may not be possible for the telecommunications industry to survive half regulated and half unregulated, which is its posture for the present. He foresees a danger that the unregulated sector may be successful in capturing all the profitable portions of the market, leaving only the unprofitable areas to the regulated sector, which will then experience serious dislocations and even system breakdowns. Avoidance of such an outcome to the deregulatory steps presently being taken will require an uncommon degree of prudence and wisdom in those state officials who remain charged with regulatory responsibility for local exchange telephone facilities and service.

1983-04-14

42

Prohibitions against the combustion of solid and liquid fuels in urban areas  

Energy Technology Data Exchange (ETDEWEB)

Much as it is accepted for pollution control reasons air pollution abatement still is the subject of heated debates. Pollutant emissions can considerably be reduced with the help of electric power supplies. In order not to prejudice electric power users tariffs have to be adapted to the prices of other energy sources available on the market. There is a general need for energy conservation, resource conservation and the reduction of carbon dioxide emissions. Thermal insulation is among the remedial measures. Fundamental air pollution abatement measures will have to be avoiding smog warnings which are known to considerably interfere with both economic and private activities.

1988-02-01

43

Landscape of international event-based biosurveillance  

Science.gov (United States)

Event-based biosurveillance is a scientific discipline in which diverse sources of data, many of which are available from the Internet, are characterized prospectively to provide information on infectious disease events. Biosurveillance complements traditional public health surveillance to provide both early warning of infectious disease events and situational awareness. The Global Health Security Action Group of the Global Health Security Initiative is developing a biosurveillance capability that integrates and leverages component systems from member nations. This work discusses these biosurveillance systems and identifies needed future studies.

2010-02-19

44

Enhancement pattern of hilar cholangiocarcinoma: Contrast-enhanced ultrasound versus contrast-enhanced computed tomography  

International Nuclear Information System (INIS)

Objective: To compare the enhancement pattern of hilar cholangiocarcinoma on contrast-enhanced ultrasound (CEUS) with that on contrast-enhanced computed tomography (CECT). Methods: Thirty-two consecutive patients with pathologically proven hilar cholangiocarcinomas were evaluated by both low mechanical index CEUS and CECT. The enhancement feature of the tumor, portal vein infiltration, and lesion conspicuity on them was investigated. Results: In the arterial phase, the numbers of the lesions showing hyperenhancement, isoenhancement, and hypoenhancement, were 14 (43.8%), 14 (43.8%), and 4 (12.6%), on CEUS, and 12 (37.5%), 9 (28.1%), and 11 (34.4%), on CECT (P = 0.162). In portal phase, the numbers of the lesions showing hypoenhancement, isoenhancement, and hyperenhancement were 30 (93.8%), 1 (3.1%), and 1 (3.1%), on CEUS, and 23 (71.9%), 8 (25.0%), and 1 (3.1%), on CECT (P = 0.046). The detection rates for portal vein infiltration were 84.2% (16/19) for baseline ...

2010-08-01

45

Computerized Tomography versus unenhanced and enhanced fast MRI sequences in the study of liver metastases: Qualitative and quantitative analyses  

International Nuclear Information System (INIS)

The authors compared unenhanced and contrast-enhanced fast MRI and Computerized Tomography in the detection of liver metastases. Eleven patients with single or multiple hepatic lesions (42 in all) were submitted to V and magnetic resonance studies; T1- and T2- weighted TSE, T2-weighted TSE with fat suppression, unenhanced breath-hold TFE and early or delayed enhanced breath-hold TFE images were acquired with a 1.5 T superconductive magnet (Philips NT). The quantitative analysis of all magnetic resonance images was performed for contrast/noise ratio (CNR) and number of detected lesions; magnetic resonance and Computerized Tomography images were also compared qualitatively for lesion conspicuity, anatomical structure identification and artifacts. The results were compared with Student's test. Early enhanced breath-hold TFE was statistically superior to T1-weighted TSE (p = .0009), T2-weighted TSE (p = .01) and Computerized Tomography ( p = .0004) for lesion ...

1997-01-01

46

Power system stabilizer system having improved integrity checking scheme  

Energy Technology Data Exchange (ETDEWEB)

This patent describes improvement in a system for stabilizing the operation of an electrical generator connected to a power distribution network of the type including a power system stabilizer for providing an oscillation signal having a value which normally represents generator oscillations and a modulator circuit responsive to input signals including the oscillation signal to provide a modulated output signal for varying generator excitation, means for checking for operational integrity of the power system stabilizer. It comprises: means for applying, to the power system stabilizer, a test signal of known amplitude and frequency, the test signal simulating generator oscillations and serving to produce a simulated oscillation signal for employment as the oscillation signal, means to store representations of time related ...

1991-03-12

47

Negative frequency and complex-carrier modulation and demodulation  

CERN Document Server

Negative frequency has a physical meaning, the complete description of a frequency signal is a rotating complex signal, in complete description, positive frequency signal exp(iwt) and negative frequency signal exp(-iwt) is two distinguishable and independent frequency signals. Because the real-carrier modulation and demodulation do not distinguish positive and negative frequency, so half of the spectrum resources and signal energy are wasted. The complex-carrier modulation uses the distinguishable positive frequency signal exp(iwt) and negative frequency signal exp(-iwt) as the carrier signals, they can carry different information, so the spectrum resources is full used, the complex-carrier demodulation does not lose signal energy, so the spectrum efficiency is improved.

2010-01-01

48

Application of wavelet analysis to signal processing methods for eddy-current test; ueburetto kaiseki no kadenryushinshoho heno tekiyo  

Energy Technology Data Exchange (ETDEWEB)

This study deals with the application of wavelet analysis to detection and characterization of defects from eddy-current and ultrasonic testing signals of a low signal-to-noise ratio. Presented in this paper are the methods for processing eddy-current testing signals of heat exchanger tubes of a steam generator in a nuclear power plant. The results of processing eddy-current testing signals of tube test pieces with artificial flaws show that the flaw signals corrupted by noise and/or non-defect signals can be effectively detected and characterized by using the wavelet methods. (author)

1998-12-15

49

Device for controlling water supply to nuclear reactor  

International Nuclear Information System (INIS)

Object: To smoothly control automatic water supply for realizing stable operation of a nuclear reactor by providing a flow rate limiting signal selection circuit and a preferential circuit in a water supply control device for a nuclear reactor wherein the speed of a recirculation pump may be changed in two-steps. Structure: Opening angle signals for a water supply regulating valve are controlled by a nuclear reactor water level signal, a vapor flow rate signal and a supplied water flow rate signal through an adder and an adjuster in response to a predetermined water level setting signal. When the water in the reactor is maintained at a predetermined level, a selection circuit receives a water pump condition signal for selecting one of the signals from a supplied water rate limiting signal generator ...

50

The Stellar Populations of Low Luminosity Active Galactic Nuclei. III: Spatially Resolved Spectral Properties  

CERN Document Server

In a recent survey of the stellar populations of LINERS and LINER/HII Transition Objects (TOs) we identified a numerous class of nuclei which stand out because of their conspicuous 10^8-9 yr populations. These objects were called ``Young-TOs'', since they all have TO-like emission line ratios. In this paper we investigate the radial variations of spectral properties in Low Luminosity AGN. Our analysis is based on high S/N, 3500-5500 A, long-slit spectra for 47 galaxies. The data probe distances of typically up to 850 pc from the nucleus with a resolution of ~ 100 pc and S/N ~ 30. Stellar population gradients are mapped by the radial profiles of absorption line equivalent widths and colours along the slit. These variations are further analyzed by means of a decomposition of each spectrum in terms of template galaxies representative of very young (<= 10^7 yr), intermediate age (10^8-9 yr) and old (10^10 yr) populations. Our main findings are: (1) Significant ...

2004-01-01

51

Single-Electrode Transient Behavior for Electric Double Layer Capacitor Composed of Nano-Porous Carbon Electrode; Kasseitan denki 2jyuso kyapasita no tankyoku jyuhoden katei ni taisuru sokudoronteki kento  

Energy Technology Data Exchange (ETDEWEB)

Single-electrode transient behavior was measured mainly during the discharging process for a model cell of electric double layer capacitor with nano-porous carbon electrodes and reference electrode. Apparent conductivity in the cell, which we call `effective conductivity,` is determined with approximation of current in transient behavior to a one-dimensional electrophoretic model. A comparison of effective conductivity with conductivity of bulk solution suggests an interesting mechanism of transfer of electrolyte ions. The difference in transient behavior between various electrolyte ions was not conspicuous in spite of distinctive differences in conductivity of each bulk solution. The large pore diameter of the carbon electrode results in rapid transient behavior and such an electrode should be suitable for rapid charge and discharge. The effect of origin of carbon electrode is found to be significant to bring considerable differences in discharge rate. However, ...

1997-07-10

52

Simultaneous assessment of left ventricular function from gated myocardial perfusion SPECT. Utility of QGS (Quantitative Gated SPECT) program  

International Nuclear Information System (INIS)

Quantitative gated SPECT (QGS) was evaluated in 7 normal volunteers and 31 patients with cardiac diseases. Adequate cut off value of a prefilter was 0.45. In phantom, the left ventricular volume value was 93.9% of determined value by 180-degree projection in L type and 98.8% by 360-degree projection in opposed type. In normal volunteers, LVEF measured by QGS program related to value by first pass method. As for functional map, regional EF and wall motion decreased at the septum side, and wall thickening at base side of heart. Good correlation was recognized (p<0.0001) between blood flow image and functional map (regional EF and wall thickening). In 20 cases of acute myocardial infarction, lesion was detected conspicuously in regional EF and wall motion. The accuracy of coronary arterial stenosis improved in functional map (regional EF 92%, wall motion 92% and wall thickening 88%). In particular, the accuracy of 3 rami lesion was 100% in functional map and higher ...

1998-08-01

53

HD 100453: A Link Between Gas-Rich Protoplanetary Disks and Gas-Poor Debris Disks  

CERN Document Server

HD 100453 has an IR spectral energy distribution (SED) which can be fit with a power-law plus a blackbody. Previous analysis of the SED suggests that the system is a young Herbig Ae star with a gas-rich, flared disk. We reexamine the evolutionary state of the HD 100453 system by refining its age (based on a candidate low-mass companion) and by examining limits on the disk extent, mass accretion rate, and gas content of the disk environment. We confirm that HD 100453B is a common proper motion companion to HD 100453A, with a spectral type of M4.0V - M4.5V, and derive an age of 10 +/- 2 Myr. We find no evidence of mass accretion onto the star. Chandra ACIS-S imagery shows that the Herbig Ae star has L_X/L_Bol and an X-ray spectrum similar to non-accreting Beta Pic Moving Group early F stars. Moreover, the disk lacks the conspicuous Fe II emission and excess FUV continuum seen in spectra of actively accreting Herbig Ae stars, and from the FUV continuum, we find the ...

2009-01-01

54

EVIDENCE FOR DELAYED MASSIVE STAR FORMATION IN THE M17 PROTO-OB ASSOCIATION  

International Nuclear Information System (INIS)

Through analysis of archival images and photometry from the Spitzer GLIMPSE and MIPSGAL surveys combined with Two Micron All Sky Survey and MSX data, we have identified 488 candidate young stellar objects (YSOs) in the giant molecular cloud M17 SWex, which extends #approx#50 pc southwest from the prominent Galactic H II region M17. Our sample includes >200 YSOs with masses >3 M _s_u_n that will become B-type stars on the main sequence. Extrapolating over the stellar initial mass function (IMF), we find that M17 SWex contains >1.3 x 10"4 young stars, representing a proto-OB association. The YSO mass function is significantly steeper than the Salpeter IMF, and early O stars are conspicuously absent from M17 SWex. Assuming M17 SWex will form an OB association with a Salpeter IMF, these results reveal the combined effects of (1) more rapid circumstellar disk evolution in more massive YSOs and (2) delayed onset of massive star formation.

2010-05-10

55

Computed radiography in X-ray examination of stomach. Evaluation by phantom experiments and clinical studies  

Energy Technology Data Exchange (ETDEWEB)

The usefulness and clinical applicability of computed radiography(FCR) in X-ray examination of the stomach were evaluated in comparison with film-screen (FS) radiography by both phantom experiments and clinical studies. Receiver operating characteristic (ROC) curve analysis consisting of 25 normal and 25 artificially created simulated lesions on an orginally created Styrofoam phantom showed no difference in lesion detectability between FCR and FS radiography. Both were also equal in evaluation of the internal structure and margin of the 25 lesions by visual ranking. ROC curve analysis of clinical cases was performed in 30 cases, 20 normal and 10 abnormal, while evaluation by visual ranking was performed on 18 lesions. There was no significant difference between FCR and FS radiography either with ROC curve analysis or visual ranking, although the variations were somewhat greater in the clinical cases than in the phantom studies. I conclude that FCR is equal to FS radiography in X-ray ...

1995-08-01

56

Computed radiography in X-ray examination of stomach. Evaluation by phantom experiments and clinical studies  

International Nuclear Information System (INIS)

The usefulness and clinical applicability of computed radiography(FCR) in X-ray examination of the stomach were evaluated in comparison with film-screen (FS) radiography by both phantom experiments and clinical studies. Receiver operating characteristic (ROC) curve analysis consisting of 25 normal and 25 artificially created simulated lesions on an orginally created Styrofoam phantom showed no difference in lesion detectability between FCR and FS radiography. Both were also equal in evaluation of the internal structure and margin of the 25 lesions by visual ranking. ROC curve analysis of clinical cases was performed in 30 cases, 20 normal and 10 abnormal, while evaluation by visual ranking was performed on 18 lesions. There was no significant difference between FCR and FS radiography either with ROC curve analysis or visual ranking, although the variations were somewhat greater in the clinical cases than in the phantom studies. I conclude that FCR is equal to FS radiography in X-ray ...

1995-01-01

57

The bacterial signal indole increases epithelial-cell tight-junction resistance and attenuates indicators of inflammation  

UK PubMed Central (United Kingdom)

Interkingdom signaling is established in the gastrointestinal tract in that human hormones trigger responses in bacteria; here, we show that the corollary is true, that a specific bacterial signal,...Full Text Available

2010-01-05

58

Social competition affects electric signal plasticity and steroid levels in the gymnotiform fish Brachyhypopomus gauderio  

UK PubMed Central (United Kingdom)

Sexually-selected communication signals can be used by competing males to settle contests without incurring the costs of fighting. Steroid regulation of these signals can render them as reliable...Full Text Available

2009-10-01

59

Mutational Analysis of cis-Acting RNA Signals in Segment 7 of Influenza A Virus?  

UK PubMed Central (United Kingdom)

The genomic viral RNA (vRNA) segments of influenza A virus contain specific packaging signals at their termini that overlap the coding regions. To further characterize cis-acting signals...Full Text Available

2008-12-01

60

Colour television, an imitation of the human visual system.  

UK PubMed Central (United Kingdom)

Colour television is examined as an attempt to imitate the human visual system in image formation, spectral sensitivities, adaptation, contrast effects, signal processing, signal modulation, signal...Full Text Available

1975-07-01

61

The cross-coupled interferometer for gravitational wave detection  

International Nuclear Information System (INIS)

The cross-coupled interferometer is a new design for interferometric gravitational wave detectors. Similar to the baseline gravitational wave detectors proposed for Advanced LIGO, it uses long-arm cavities in which the signal is generated. The signal fields are then extracted from the arm cavities with an additional cavity behind the long-arm cavities. The tuning of this signal extraction cavity and the parallel tuning of the signal recycling mirror can be used to optimize the peak frequency and the bandwidth of the detector independently. If we replace the signal recycling mirror by a small cavity, it is possible to amplify signals in two different frequency bands.

2002-04-07

62

RATIO COMPUTER  

Science.gov (United States)

An electronic computer circuit is described for producing an output voltage proportional to the product or quotient of tbe voltages of a pair of input signals. ln essence, the disclosed invention provides a computer having two channels adapted to receive separate input signals and each having amplifiers with like fixed amplification factors and like negatlve feedback amplifiers. One of the channels receives a constant signal for comparison purposes, whereby a difference signal is produced to control the amplification factors of the variable feedback amplifiers. The output of the other channel is thereby proportional to the product or quotient of input signals depending upon the relation of input to fixed signals in the first mentioned channel.

1958-11-11

63

Infrared stimulated luminescence in quartz  

Energy Technology Data Exchange (ETDEWEB)

Infrared (IR, 880 nm) stimulated luminescence (IRSL) signal was observed from quartz at room temperature. The characteristics of the signal such as its response to {gamma}-ray irradiation, thermal stability and thermal assistance energy show that the signal originates from different traps than those responsible for the luminescence signal stimulated by green light (GL, 514 nm). The IRSL signal's short lifetime (18 days at 15 deg. C) may have been the reason why it was not detected in previous experiments. The decay of the IR signal after GL illumination was observed. The thermoluminescence at 76 deg. C was enhanced after IR illumination.

2005-02-01

64

Neural network and noise injection for the modeling of ozone pollution; Reseau de neurones et injection de bruit pour la modelisation de la pollution par l'ozone  

Energy Technology Data Exchange (ETDEWEB)

This study has been carried out in the framework of a collaboration between the laboratory of processes automation (LAP, Caen (France)), and Air Com, a monitoring network for the prevention of atmospheric pollution in Basse-Normandie. It aims at obtaining a medium and long term forecast of the ozone level above the Caen city. The expected goal is to foresee the pollution peaks exceeding the warning thresholds, but the rareness of such events make them more difficult to predict. In order to solve this kind of problem, a neural modeling method combined with a noise injection technique has been implemented in order to obtain a sufficiently performing model over the whole domain of operation. (J.S.)

2001-07-01

65

Experimental study of neutron noise with criticality safety applications in mind  

Energy Technology Data Exchange (ETDEWEB)

A study has been conducted on the statistics of detected neutrons that leaked from four subcritical reflected, enriched-uranium assemblies, to explore the feasibility of developing a criticality warning system based on neutron noise analysis. Studies were conducted on three possible discriminators, i.e., three signatures that might be used to discriminate among assemblies of various multiplications. The noise analysis techniques studied performed well enough in deeply subcritical situations to deserve testing in an applications environment. They have a good chance of detecting changes in reactivity that are potentially dangerous. One can expect sharpest results when doing comparisons, i.e., when comparing two records, one taken in the past under circumstances known to be normal and one taken now to search for change.

1985-11-01

66

Control rod drives  

International Nuclear Information System (INIS)

Purpose: To secure the reactor operation safety by the provision of a fluid pressure detecting section for control rod driving fluid and a control rod interlock at the midway of the flow pass for supplying driving fluid to the control rod drives. Constitution: Between a driving line and a direction control valve are provided a pressure detecting portion, an alarm generating device, and a control rod inhibition interlock. The driving fluid from a driving fluid source is discharged by way of a pump and a manual valve into the reactor in which the control rods and reactor fuels are contained. In addition, when the direction control valve is switched and the control rods are inserted and extracted by the control rod drives, the pressure in the driving line is always detected by the pressure detection section, whereby if abnormal pressure is resulted, the alarm generating device is actuated to warn the abnormality and the control rod inhibition interlock is actuated to ...

67

Application of PDA forest fire monitoring based on web service technology  

British Library Electronic Table of Contents (United Kingdom)

The difficulty in information communication and sharing are major problems for forest fire monitoring and early warning in China. As authors, we applied web service technology to a personal digital assistant (PDA) forest fire monitoring system and propose the framework of a monitoring system based on service-oriented architecture (SOA). At the same time, we describe the composition and function of web services from a server side and a client side. The method for developing a web service invocation engine on the PDA is introduced in detail. Finally, an example of a fire danger rating and fire weather services system are established, based on the Beijing Forest Fire Control System. The results show that the PDA forest fire monitoring system based on web services can effectively take advantag...

2009-01-01

68

Use of Morphological Signal Processing and Computational - NASA  

Science.gov (United States)

Al-Balushi KR, Samanta B. Gear fault diagnosis using energy-based features of acoustic emission signals. Proc. IMechE, Part I: ...

69

Self-Motion and the Shaping of Sensory Signals  

UK PubMed Central (United Kingdom)

Sensory systems must form stable representations of the external environment in the presence of self-induced variations in sensory signals. It is also possible that the variations themselves may provide...Full Text Available

2010-04-01

70

Extracellular Signaling through the Microenvironment: A Hypothesis Relating Carcinogenesis, Bystander Effects, and ...  

Science.gov (United States)

... Extracellular Signaling through the Microenvironment: A Hypothesis Relating Carcinogenesis, Bystander Effects, and Genomic InstabilityMary Helen Barcellos-Hoff1a ... ...

71

Dishonest signalling in a fiddler crab.  

UK PubMed Central (United Kingdom)

Animal communication theory predicts that low-frequency cheating should be common in generally honest signalling systems. However, perhaps because cheats are designed to go undetected, there are few...Full Text Available

2000-04-07

72

Control of Host Cell Phosphorylation by Legionella Pneumophila  

UK PubMed Central (United Kingdom)

Phosphorylation is one of the most frequent modifications in intracellular signaling and is implicated in many processes ranging from transcriptional control to signal transduction in innate immunity....Full Text Available

73

A comprehensive assessment of N-terminal signal peptides prediction methods  

UK PubMed Central (United Kingdom)

BackgroundAmino-terminal signal peptides (SPs) are short regions that guide the targeting of secretory proteins to the correct subcellular compartments in the cell. They are cleaved...Full Text Available

82

Fault diagnosis of rolling bearing based on cyclic spectrum density  

International Nuclear Information System (INIS)

The paper considered the vibration signals of rotating equipment as cyclo stationary signals through analyzing the features of this kind of signals. Based on the analytic method of cyclic spectrum density, the paper pointed out that the impact frequency could be extracted effectively with the help of scanning cyclic frequency domain. The validity of the method of cyclic spectrum density is proved by simulating signals and the method is applied to the diagnosis of rolling bearings. (authors)

2009-09-01

84

Climate Change in the 20th and 21st Centuries  

ScienceCinema

...of the and global warming signal so ...

85

The envelope order spectrum based on generalized demodulation time-frequency analysis and its application to gear fault diagnosis  

British Library Electronic Table of Contents (United Kingdom)

The generalized demodulation time-frequency analysis is a novel signal processing method, which is particularly suitable for the processing of multi-component amplitude-modulated and frequency-modulated (AM-FM) signals as it can decompose a multi-component signal into a set of single-component signals whose instantaneous frequencies own physical meaning. While fault occurs in gear, the vibration signals measured from gearbox would exactly display AM-FM characteristics. Therefore, targeting the modulation feature of gear vibration signal in run-ups and run-downs, a fault diagnosis method in which generalized demodulation time-frequency analysis and envelope order spectrum technique are combined is put forward and applied to the transient analysis of gear vibration signal. Firstly the multi-...

2010-01-01

86

Comparison of the green- and infrared-stimulated luminescence of feldspar  

Energy Technology Data Exchange (ETDEWEB)

The differences are highlighted of various aspects of behaviour of the luminescence signal from feldspar when stimulated by green light and when stimulated by infrared radiation. In respect of bleaching, a comparison is made of the influence of white light (daylight) on the two stimulated luminescence signals, as well as a comparison of the influence of infrared exposure on the green-stimulated signal with the influence of green exposure on the infrared-stimulated signal. The influence of preheating on the two stimulated signals is also compared. Light-emitting diode systems were used for both green and infrared stimulation. The observations are considered in relation to the mechanism relevant to green- and infrared-stimulated luminescence from feldspar. (author).

1994-04-01

87

Comparison of the green- and infrared-stimulated luminescence of feldspar  

International Nuclear Information System (INIS)

The differences are highlighted of various aspects of behaviour of the luminescence signal from feldspar when stimulated by green light and when stimulated by infrared radiation. In respect of bleaching, a comparison is made of the influence of white light (daylight) on the two stimulated luminescence signals, as well as a comparison of the influence of infrared exposure on the green-stimulated signal with the influence of green exposure on the infrared-stimulated signal. The influence of preheating on the two stimulated signals is also compared. Light-emitting diode systems were used for both green and infrared stimulation. The observations are considered in relation to the mechanism relevant to green- and infrared-stimulated luminescence from feldspar. (author).

1993-07-01

88

An intracranial aspergilloma with low signal on T2-weighted images corresponding to iron accumulation  

Energy Technology Data Exchange (ETDEWEB)

We present a case of cerebral aspergillosis in an immunocompetent patient. The MRI signal characteristics were compared with the histologic findings. Irregular low-signal zones were demonstrated between the wall of the abscess and the central necrosis on T2-weighted images; the pathology specimen revealed concentrated iron in these transitional zones but no hemosiderin. Iron is an essential element for the growth of fungal hyphae. The low-signal zones may represent the areas where there was active proliferation of aspergillus, and the unique location of the low signal may be a helpful imaging characteristic for the diagnosis of an aspergillus abscess. (orig.)

2001-07-01

89

A gear fault diagnosis using Hilbert spectrum based on MODWPT and a comparison with EMD approach  

British Library Electronic Table of Contents (United Kingdom)

When gear fault occurs, the vibration signals always display non-stationary behavior. Therefore time-frequency analysis has become the well-accepted technique for vibration-based gear fault diagnosis. This paper presents the application of a new time-frequency signal processing technique, the Hilbert spectrum based on the maximal overlap discrete wavelet packet transform (MODWPT), to the analysis of simulation signals and gear fault vibration signals measured by the acceleration sensor fixed on the bearing house. As long as the decomposition scale and disjoint dyadic decomposition are chosen suitably, the original signal could be decomposed into a set of monocomponent signals whose instantaneous amplitude and instantaneous frequency own physical meaning. After the instantaneous amplitude a...

2009-01-01

90

The envelope order spectrum based on generalized demodulation time-frequency analysis and its application to gear fault diagnosis  

Science.gov (United States)

The generalized demodulation time-frequency analysis is a novel signal processing method, which is particularly suitable for the processing of multi-component amplitude-modulated and frequency-modulated (AM-FM) signals as it can decompose a multi-component signal into a set of single-component signals whose instantaneous frequencies own physical meaning. While fault occurs in gear, the vibration signals measured from gearbox would exactly display AM-FM characteristics. Therefore, targeting the modulation feature of gear vibration signal in run-ups and run-downs, a fault diagnosis method in which generalized demodulation time-frequency analysis and envelope order spectrum technique are combined is put forward and applied to the transient analysis of gear vibration signal. Firstly the multi-component vibration signal of ...

2010-02-01

91

Unearthing black gold  

Energy Technology Data Exchange (ETDEWEB)

Preventing recurrence of surface mining accidents in the coal industry remains a top priority requiring constant vigilance and a substantial commitment from all involved in open pit mining operations. Open pit wall failures, loose rocks rolling down slopes, ground water and stockpiling procedures are common sources of risks in open cut coal operations. This video aims to equip workers with the necessary skills and knowledge to assess and react to the geomechanics hazards in open pit coal operations. Workers need to have the competencies to manage geomechanics hazards to facilitate their own and their workmates' safety. No matter how good the operating systems are, the first line of defence against accidents is the experience, skill and knowledge-based judgment of each individual mine worker. The video covers: Open pit coal mine risk management and geomechanical issues; Terminology, mining cycle, and explanation of pit slope hazards; and Understanding of pit slope failures and ...

2004-07-01

92

The mask detection technology for occluded face analysis in the surveillance system.  

Science.gov (United States)

The surveillance systems have been widely used in automatic teller machines (ATMs), banks, convenient stores, etc. For example, when a customer uses the ATM, the surveillance systems will record his/her face information. The information will help us understand and trace who withdrew money. However, when criminals use the ATM to withdraw illegal money, they usually block their faces with something (in Taiwan, criminals usually use safety helmets or masks to block their faces). That will degrade the purpose of the surveillance system. In previous work, we already proposed a technology for safety helmet detection. In this paper, we propose a mask detection technology based upon automatic face recognition methods. We use the Gabor filters to generate facial features and utilize geometric analysis algorithms for mask detection. The technology can give an early warning to save-guards when any "customer" or "intruder" blocks his/her face information with a mask. Besides, ...

2005-05-01

93

Structural and functional responses of benthic invertebrates to imidacloprid in outdoor stream mesocosms  

International Nuclear Information System (INIS)

Structural and functional responses of a benthic macroinvertebrate assemblage to pulses of the insecticide imidacloprid were assessed in outdoor stream mesocosms. Imidacloprid pulses reduced invertebrate abundance and community diversity in imidacloprid-dosed streams compared to control streams. These results correlated well with effects of imidacloprid on leaf litter decomposition and feeding rates of Pteronarcys comstocki, a stonefly, in artificial streams. Reductions in oxygen consumption of stoneflies exposed to imidacloprid were also observed in laboratory experiments. Our findings suggest that leaf litter degradation and single species responses can be sensitive ecotoxicological endpoints that can be used as early warning indicators and biomonitoring tools for pesticide contamination. The data generated illustrates the value of mesocosm experiments in environmental assessment and how the consideration of functional and structural endpoints of natural ...

94

Simulation for transient stability study of the Taiwan power system - a nuclear majority system  

Energy Technology Data Exchange (ETDEWEB)

A transient stability program was developed for the Taiwan Power Company, which has a high proportion of nuclear generation in its power system. This program offers a new territory to investigate nuclear plant effects on the power system transient stability. This program also provides a high speed tool for the Taipower system operational planning. A generalized procedure of synchronous machine modeling for a large-scale stability study is presented. The merits and weaknesses of machine modeling can be comprehended through each item of this procedure. Three types of nonlinear synchronous machine modeling implemented into this stability program are derived by following this procedure. A robust subroutine was derived to perform the fourth order Runge-Kutta integration method, making the software programming neat and systematical. For simulating the nuclear plant influence on the system, this program implemented an additional four functions: load-limit operation simulated by a low-value ...

1984-01-01

95

Simulation for transient stability study of the Taiwan power system - a nuclear majority system  

International Nuclear Information System (INIS)

A transient stability program was developed for the Taiwan Power Company, which has a high proportion of nuclear generation in its power system. This program offers a new territory to investigate nuclear plant effects on the power system transient stability. This program also provides a high speed tool for the Taipower system operational planning. A generalized procedure of synchronous machine modeling for a large-scale stability study is presented. The merits and weaknesses of machine modeling can be comprehended through each item of this procedure. Three types of nonlinear synchronous machine modeling implemented into this stability program are derived by following this procedure. A robust subroutine was derived to perform the fourth order Runge-Kutta integration method, making the software programming neat and systematical. For simulating the nuclear plant influence on the system, this program implemented an additional four functions: load-limit operation simulated by a low-value ...

96

Online monitoring of power transformers - a new low-cost system for small and medium power transformers; Monitoring von Leistungstransformatoren - Jetzt auch fuer kleine und mittlere Baugroessen  

Energy Technology Data Exchange (ETDEWEB)

Until now, monitoring of power transformers focussed mainly large generator and network transformers. Siemens goes a step ahead and provides a system especially developed and designed for small and medium power transformers, e.g. for the 100 kV level. This low cost version could be achieved by restriction to really necessary measuring quantities. This allows to realize also for small and medium power transformers an online monitoring including an estimation of aging and as an option an early warning to avoid unexpected failures. (orig.) [German] Die Ueberwachung (Monitoring) von Leistungstransformatoren war bisher vor allem fuer Maschinentransformatoren und grosse Netzkuppeltransformatoren in der Diskussion. Siemens geht einen Schritt weiter und stellt nun auch ein System bereit, das speziell fuer kleine und mittlere Leistungstransformatoren, z.B. der 110-kV-Spannungsebene, konzipiert ist. Diese kostenguenstige Variante wurde durch Beschraenkung auf die aus ...

1999-09-20

97

Mining in the Alligator Rivers Region, northern Australia: Assessing potential and actual effects on ecosystem and human health  

International Nuclear Information System (INIS)

This paper presents an overview of issues related to surface water contamination arising from uranium mining activities in the Alligator Rivers Region (ARR) of northern Australia, and a program of research and monitoring that must assess the potential and actual effects on ecosystem and human health. The program of assessing effects on aquatic ecosystems involves a four-tiered approach including the derivation of local water quality guideline trigger values, direct toxicity assessment of mine waters prior to their release, creekside or in situ monitoring for early warning of adverse effects during mine water release, and longer-term monitoring of macroinvertebrate and fish communities. Bioaccumulation in aquatic biota is also assessed, and is an issue of importance not only to ecosystem health, but also to the health of local Aboriginal people. The aquatic animals they consume represent potential sources of radiological dose, and as a result, a major component of ...

2002-12-27

98

Wnt3a Induces Myofibroblast Differentiation by Upregulating TGF-? Signaling Through SMAD2 in a ?-Catenin-Dependent Manner  

UK PubMed Central (United Kingdom)

Growing evidence suggests the Wnt family of secreted glycoproteins and their associated signaling pathways, linked to development, are recapitulated during wound repair and regeneration events. However,...Full Text Available

99

The discovery of signal transduction by G proteins. A personal account and an overview of the initial findings and contributions that led to our present understanding  

UK PubMed Central (United Kingdom)

The realization that there existed a G-protein coupled signal transduction mechanism developed gradually and was initially the result of an ill fated quest for uncovering the mechanism of action...Full Text Available

2007-04-01

100

The Receptor Tyrosine Kinase FGFR4 Negatively Regulates NF-kappaB Signaling  

UK PubMed Central (United Kingdom)

BackgroundNFκB signaling is of paramount importance in the regulation of apoptosis, proliferation, and inflammatory responses during human development and homeostasis, as...Full Text Available

101

Strange as it may seem: the many links between Wnt signaling, planar cell polarity, and cilia  

UK PubMed Central (United Kingdom)

Cilia are important cellular structures that have been implicated in a variety of signaling cascades. In this review, we discuss the current evidence for and against a link between cilia and both the...Full Text Available

2011-02-01

102

Standardization of clinical decision making for the conduct of credible clinical research in complicated medical environments.  

UK PubMed Central (United Kingdom)

The likelihood that past experience will produce correct guides to current practice depends on the signal-to-noise ratio for the clinical problem of interest. If the signal-to-noise ratio is high, the...Full Text Available

1996-01-01

103

Sodium/Calcium Exchangers Selectively Regulate Calcium Signaling in Mouse Taste Receptor Cells  

UK PubMed Central (United Kingdom)

Taste cells use multiple signaling mechanisms to generate appropriate cellular responses to discrete taste stimuli. Some taste stimuli activate G protein coupled receptors (GPCRs) that cause calcium...Full Text Available

2010-07-01

104

Signal and imaging sciences workshop proceedings  

Energy Technology Data Exchange (ETDEWEB)

Papers are presented in the areas of: Medical Technologies; Non-Destructive Evaluation; Applications of Signal/Image Processing; Laser Guide Star and Adaptive Optics; Computational Electromagnetic, Acoustics and Optics; Micro-Impulse Radar Processing; Optical Applications; TANGO Space Shuttle.

1997-11-01

105

RXR activators molecular signalling: involvement of a PPAR?-dependent pathway in the liver and kidney, evidence for an alternative pathway in the heart  

UK PubMed Central (United Kingdom)

In this study we compared the molecular signalling elicited by rexinoids, selective retinoid X receptor (RXR)-activators, in several organs (i.e. liver, kidney,...Full Text Available

2003-03-01

106

PyEEG: An Open Source Python Module for EEG/MEG Feature Extraction  

UK PubMed Central (United Kingdom)

Computer-aided diagnosis of neural diseases from EEG signals (or other physiological signals that can be treated as time series, e.g., MEG) is an emerging field that has gained much attention in past...Full Text Available

2011-01-01

107

Phosphatidic acid signaling to mTOR: Signals for the survival of human cancer cells  

UK PubMed Central (United Kingdom)

During the past decade elevated phospholipase D (PLD) activity has been reported in virtually all cancers where it has been examined. PLD catalyzes the hydrolysis of phosphatidylcholine to generate...Full Text Available

2009-09-01

108

Monitoring the Simultaneous Presentation of Spatialized Speech Signals in a Virtual Acoustic Environment.  

Science.gov (United States)

The effect of spatial auditory information on a listener's ability to detect, identify, and monitor multiple simultaneous speech signals was evaluated using virtual audio technology. Factorial combinations of three variables - the number of localized spee...

1998-01-01

109

Mapping the Spatiotemporal Dynamics of Calcium Signaling in Cellular Neural Networks Using Optical Flow  

UK PubMed Central (United Kingdom)

An optical flow gradient algorithm was applied to spontaneously forming networks of neurons and glia in culture imaged by fluorescence optical microscopy in order to map functional calcium signaling...Full Text Available

2010-08-01

110

Lnk constrains myeloproliferative diseases in mice  

UK PubMed Central (United Kingdom)

Hematopoietic stem and progenitor cell (HSPC) expansion is regulated by intrinsic signaling pathways activated by cytokines. The intracellular kinase JAK2 plays an essential role in cytokine signaling,...Full Text Available

2010-06-01

111

Listeria monocytogenes Infection Induces Prosurvival Metabolic Signaling in Macrophages?  

UK PubMed Central (United Kingdom)

Host cells use metabolic signaling through the LXRα nuclear receptor to defend against Listeria monocytogenes infection. 25-Hydroxycholesterol is a natural ligand of LXRs that...Full Text Available

2011-04-01

112

Lifespan extension by increased expression of the Drosophila homologue of the IGFBP7 tumour suppressor  

UK PubMed Central (United Kingdom)

Mammals possess multiple insulin-like growth factor (IGF) binding proteins (IGFBPs), and related proteins, that modulate the activity of insulin/IGF signalling (IIS), a conserved neuroendocrine signalling...Full Text Available

2011-02-01

113

JAK/STAT Pathways in Cytokine Signaling and Myeloproliferative Disorders  

UK PubMed Central (United Kingdom)

Hematopoiesis is the cumulative result of intricately regulated signaling pathways that are mediated by cytokines and their receptors. Studies conducted over the past 10 to 15 years have revealed that...Full Text Available

2010-10-01

114

Interictal Functional Connectivity of Human Epileptic Networks Assessed by Intracerebral EEG and BOLD Signal Fluctuations  

UK PubMed Central (United Kingdom)

In this study, we aimed to demonstrate whether spontaneous fluctuations in the blood oxygen level dependent (BOLD) signal derived from resting state functional magnetic resonance imaging (fMRI) reflect...Full Text Available

115

Insulin-Like Growth Factor I Receptor Signaling Is Required for Exercise-Induced Cardiac Hypertrophy  

UK PubMed Central (United Kingdom)

The receptors for IGF-I (IGF-IR) and insulin (IR) have been implicated in physiological cardiac growth, but it is unknown whether IGF-IR or IR signaling are critically required. We generated mice with...Full Text Available

2008-11-01

116

Functional Analysis of the Murine Cytomegalovirus Chemokine Receptor Homologue M33: Ablation of Constitutive Signaling Is Associated with an Attenuated Phenotype In Vivo?  

UK PubMed Central (United Kingdom)

The murine cytomegalovirus (MCMV) M33 gene is conserved among all betaherpesviruses and encodes a homologue of seven-transmembrane receptors (7TMR) with the capacity for constitutive signaling. Previous...Full Text Available

2008-02-01

117

Female Scent Signals Enhance the Resistance of Male Mice to Influenza  

UK PubMed Central (United Kingdom)

BackgroundThe scent from receptive female mice functions as a signal, which stimulates male mice to search for potential mating partners. This searching behavior is coupled with...Full Text Available

118

Differential interleukin-6/Stat3 signaling as a function of cellular context mediates Ras-induced transformation  

UK PubMed Central (United Kingdom)

IntroductionTyrosine phosphorylated signal transducer and activator of transcription 3 (pStat3) is expressed in numerous cancers and is required for mediating tumorigenesis. Autocrine...Full Text Available

2010-01-01

119

Characterization of Cytokinin and Adenine Transport in Arabidopsis Cell Cultures1[OA  

UK PubMed Central (United Kingdom)

Cytokinins are distributed through the vascular system and trigger responses of target cells via receptor-mediated signal transduction. Perception and transduction of the signal can occur at the plasma...Full Text Available

2008-12-01

120

Association Study of Serine Racemase Gene with Methamphetamine Psychosis  

UK PubMed Central (United Kingdom)

Experimental studies have demonstrated that not only dopaminergic signaling but also glutamatergic/NMDA receptor signaling play indispensable roles in the development of methamphetamine psychosis. Our...Full Text Available

2011-03-01

121

Artificial neural network alarm method based on signal time-frequency characteristics  

International Nuclear Information System (INIS)

On the problem of alarm when parts are falling in nuclear power plant, the artificial neural network (ANN) alarm method based on the signal time-frequency characteristics was developed. The method was realized by the improved BP algorithm, and demonstrated with the data from simulation experiments

1998-06-01

122

49 CFR 236.206 - Battery or power supply with respect to relay; location.  

Science.gov (United States)

...2010-10-01 2010-10-01 false Battery or power supply with respect to relay...Signal Systems Standards § 236.206 Battery or power supply with respect to relay; location. The battery or power supply for each signal...

2010-10-01

127

NEUROPLASTICITY and INNOVATION  

Science.gov (United States)

OF VOCALIZED SPEECH THROUGH. ANALYSIS OF NEURAL SIGNALS. " SYNTHETIC TELEPATHY- WIRELESS. TRANSMISSION OF DECODED. THOUGHTS. " IMPLANTABLE MEMORY-ELIMINATES ...

129

FADC signal reconstruction for the MAGIC telescope  

Energy Technology Data Exchange (ETDEWEB)

Until April 2007 the Major Atmospheric Gamma ray Imaging Cherenkov (MAGIC) telescope used a 300 MSamples/s flash analog-to-digital converter (FADC) system to sample the shaped photomultiplier tube (PMT) signals produced by the captured Cherenkov photons of air showers. Different algorithms to reconstruct the signal from the read-out samples (extractors) have been implemented and are described and compared. Criteria based on the obtained charge and time resolution/bias are defined and used to judge the different extractors, by applying them to calibration, cosmic and pedestal signals. The achievable charge and time resolution have been derived as functions of the number of incident photo-electrons.

2008-09-11

130

Enabling Lightwave Electronics with Nanotechnology ...  

Science.gov (United States)

... Acousto-optic programmable dispersive filters (AOPDF) have been developed for optical signal processing, polarization switching in lasers, and ...

2011-03-29

131

Development and Calibration of Two and Four Wire Water ...  

Science.gov (United States)

... measurement. Power spectral density measurements are made by the dynamic signal analyzer for each channel. A cross power ...

1992-12-01

135

Visual search behaviour in skeletal radiographs: a cross-speciality study  

Energy Technology Data Exchange (ETDEWEB)

Aim: To determine whether experience improves the consistency of visual search behaviour in fracture identification in plain radiographs, and the effect of specialization. Material and methods: Twenty-five observers consisting of consultant radiologists, consultant orthopaedic surgeons, orthopaedic specialist registrars, orthopaedic senior house officers, and accident and emergency senior house officers examined 33 skeletal radiographs (shoulder, hand, and knee). Eye movement data were collected using a Tobii 1750 eye tracker with levels of diagnostic confidence collected simultaneously. Kullback-Leibler (KL) divergence and Gaussian mixture model fitting of fixation distance-to-fracture were used to calculate the consistency and the relationship between discovery and reflective visual search phases among different observer groups. Results: Total time spent studying the radiograph was not significantly different between the groups. However, the expert groups had a higher number of true ...

2007-11-15

136

New MR techniques in diagnostic imaging of joints; Neue MRT-Techniken in der Gelenkdiagnostik  

Energy Technology Data Exchange (ETDEWEB)

Already, MR Imaging is superior in diagnostic imaging of joints in many cases; however, there have been recent developments, which are the subjects of this paper. With gradient-echo sequences acquired in 3D technique, it is possible to produce high-resolution images of joints in acceptable scantime, because gradient-echo sequences are less time-consuming than convential SE sequences. With the acquisition of two echoes, phase difference between water and fat protons have to be considered. 3D Imaging is capable of displaying complex pathology in a superior way, which should be useful in preoperative planning. Tissue contrast is altered by fat saturation or magnetization transfer in order to achieve better conspicuity of lesions. Although diagnostic value of some of these options is not yet clear and further clinical studies are needed, they are a promising possibility for improving MR Imaging of the joints. (orig.) [Deutsch] In der Gelenkdiagnostik gibt es einige ...

1993-12-31

137

Friction and wear properties of glass fiber reinforced nylons against alumina ceramics in oil; Yuchu ni okeru glass sen`i kyoka nylon no alumina ceramics ni taisuru masatsu mamo tokusei  

Energy Technology Data Exchange (ETDEWEB)

The friction and wear properties of glass fiber reinforced composites of nylons (nylon 6, nylon 66 and nylon 46) with different crystallinities due to their molecular structures were investigated by sliding them with alumina ceramics and using a pin-on-disk friction machine. The friction coefficients of the glass fiber reinforced nylons in oil were lower and more stable than those in air from the initial stage of friction. The transfer of nylon matrix to adhere onto the alumina surface in air was so much greater than in oil that the alumina surface could not be recognized. Consequently, a different between the friction and wear properties in air and in oil was resulted. Reinforcement of nylons with glass fiber remarkably improved their friction properties in oil by its lubricating action, while the wears were rather high contrary to what was expected. This tendency was conspicuous for nylon 46 with high crystallinity. Breakage and extracting of glass fibers from ...

1997-09-01

138

Diagnostic and therapeutic evaluation of "1"1"1In-vinorelbine-liposomes in a human colorectal carcinoma HT-29/luc-bearing animal model  

International Nuclear Information System (INIS)

Colorectal carcinoma is a highly prevalent and common cause of cancer in Taiwan. There is still no available cure for this malignant disease. To address this issue, we applied the multimodality of molecular imaging to explore the efficacy of diagnostic and therapeutic nanoradiopharmaceuticals in an animal model of human colorectal adenocarcinoma [colorectal cancer (CRC)] that stably expresses luciferase (luc) as a reporter. In this study, an in vivo therapeutic efficacy evaluation of dual-nanoliposome (100 nm in diameter) encaged vinorelbine (VNB) and "1"1"1In-oxine on HT-29/luc mouse xenografts was carried out. HT-29/luc tumor cells were transplanted subcutaneously into male SCID mice. Multimodality of molecular imaging approaches including bioluminescence imaging (BLI), gamma scintigraphy, whole-body autoradiography (WBAR) and in vivo tumor growth tracing, histopathology and biochemistry/hematology analyses were applied on xenografted SCID mice to study the treatments with 6% ...

2008-07-01

139

Accumulation of carbon in northern mire ecosystems  

Energy Technology Data Exchange (ETDEWEB)

The basic feature in the functional ecology of any mire ecosystem is retardation of the effective decay of organic material resulting in a conspicuous accumulation of plant debris as peat overtime. The carbon accumulation process is slow, and climatic change may have an impact on the carbon cycle of peatlands, therefore, it has been of interest to study the rate of carbon accumulation by geological methods from dated peat strata. The approach is hampered by several facts. First, the mires vary enormously as to their vegetation and hydrology and hence their production and decay properties. It follows that a great number of study sites are needed. Second, the peat in mires expands both vertically and laterally, and this requires a spatial reconstruction of carbon accumulation within a mire basin. Third, simple geological methods cannot account for the actual rate of carbon accumulation in peat, and finally, an additional carbon sink in the mire ecosystems can be the ...

1996-12-31

140

Spectroscopic detection  

Energy Technology Data Exchange (ETDEWEB)

In embodiments, spectroscopic monitor monitors modulated light signals to detect low levels of contaminants and other compounds in the presence of background interference. The monitor uses a spectrometer that includes a transmissive modulator capable of causing different frequency ranges to move onto and off of the detector. The different ranges can include those with the desired signal and those selected to subtract background contributions from those with the desired signal. Embodiments of the system are particularly useful for monitoring metal concentrations in combustion effluent.

2003-01-01

141

Signal processing methods for MFE plasma diagnostics  

Energy Technology Data Exchange (ETDEWEB)

The application of various signal processing methods to extract energy storage information from plasma diamagnetism sensors occurring during physics experiments on the Tandom Mirror Experiment-Upgrade (TMX-U) is discussed. We show how these processing techniques can be used to decrease the uncertainty in the corresponding sensor measurements. The algorithms suggested are implemented using SIG, an interactive signal processing package developed at LLNL.

1985-02-01

142

Optimal Quantum State Estimation by No-Signaling Principle  

CERN Document Server

We obtain a simple derivation of the optimal quantum state estimation of a two-level system using the no-signaling principle. In particular, we show that the no-signaling principle determines the unique form of the guessing probability, independently to a given figure of merit such as the fidelity or the information gain. This proves that optimal measurements for a two-level quantum system is the same for almost all figures of merit.

2010-01-01

143

ATP-gated P2X3 receptors constitute a positive autocrine signal for insulin release in the human pancreatic ? cell  

UK PubMed Central (United Kingdom)

Extracellular ATP has been proposed as a paracrine signal in rodent islets, but it is unclear what role ATP plays in human islets. We now show the presence of an ATP signaling pathway that enhances...Full Text Available

2010-04-06

144

Cyclic Spectral Analysis of Radio Pulsars  

CERN Document Server

Cyclic spectral analysis is a signal processing technique designed to deal with stochastic signals whose statistics vary periodically with time. Pulsar radio emission is a textbook example of this signal class, known as cyclostationary signals. In this paper, we discuss the application of cyclic spectral analysis methods to pulsar data, and compare the results with the traditional filterbank approaches used for almost all pulsar observations to date. In contrast to standard methods, the cyclic spectrum preserves phase information of the radio signal. This feature allows us to determine the impulse response of the interstellar medium and the intrinsic, unscattered pulse profile directly from a single observation. We illustrate these new analysis techniques using real data from an observation of the millisecond pulsar B1937+21.

2011-01-01

145

A Preliminary Investigation of the Reinforcement Function of Signal Detections in Simulated Baggage Screening: Further Support for the Vigilance Reinforcement Hypothesis  

Science.gov (United States)

The vigilance reinforcement hypothesis (VRH) asserts that errors in signal detection tasks are partially explained by operant reinforcement and extinction processes. VRH predictions were tested with a computerized baggage screening task. Our experiment evaluated the effects of signal schedule (extinction vs. variable interval 6 min) and visual field complexity (dial vs. baggage x-ray) on search behavior rates. There was a main effect for signal schedule [F (1, 20) = 14.0, p = 0.001, p[subscript rep] = 0.99], but no effects for field complexity or interaction. The VRH suggests that performance errors in visual screening work may be reduced through operant conditioning of search behaviors by intensive management of artificially planted signals. (Contains 1 table and 3 figures.)

2008-12-01

146

A simple 5-DoF MR-compatible motion signal measurement system.  

Science.gov (United States)

The purpose of this study was to develop a simple motion measurement system with magnetic resonance (MR) compatibility and safety. The motion measurement system proposed here can measure 5-DoF motion signals without deteriorating the MR images, and it has no effect on the intense and homogeneous main magnetic field, the temporal-gradient magnetic field (which varies rapidly with time), the transceiver radio frequency (RF) coil, and the RF pulse during MR data acquisition. A three-axis accelerometer and a two-axis gyroscope were used to measure 5-DoF motion signals, and Velcro was used to attach a sensor module to a finger or wrist. To minimize the interference between the MR imaging system and the motion measurement system, nonmagnetic materials were used for all electric circuit components in an MR shield room. To remove the effect of RF pulse, an amplifier, modulation circuit, and power supply were located in a shielded case, which was made ...

2011-09-01

147

The influence of electromagnetic field irradiated by high-voltage transmission lines on properties of cells.  

Science.gov (United States)

The influence of low-frequency electromagnetic field irradiating by high-voltage transmission lines on signal transduction of cell in spleen cells of the rates have been studied by molecular-biology techniques. The spleen cells are extracted from skilled rates, which are exposed in the electromagnetic field of high-voltage transmission lines with 4000 V/m and 0.09-0.1 G about 400 days. The quantity or level of phosphorylation of signal transducer and activator of transcription (STAT3) in JAK-STAT signal transduction pathway of spleen cells, which are stimulated and unstimulated by IL-2, respectively, are detected by the immunoblotting and immunobiochemistry. The results show that the expression of phospho-STAT3 in spleen cell stimulated by IL-2 differ not from that in the unstimulated cell. The former is significantly large than the latter. This shows that signal transduction of cell is affected by this ...

2005-01-01

148

Signal Processing in Large Systems: a New Paradigm  

CERN Document Server

For a long time, signal processing applications, and most particularly detection and parameter estimation methods, have relied on the limiting behaviour of test statistics and estimators, as the number n of observations of a population grows large comparatively to the population size N, i.e. n>>N. Modern technological and societal advances now demand the study of sometimes extremely large populations, while simultaneously requiring fast signal processing due to accelerated system dynamics; this results in not-so-large practical ratios n/N, sometimes even smaller than one. A disruptive change in classical signal processing methods has therefore been initiated in the past ten years, mostly spurred by the field of large dimensional random matrix theory. The early literature in random matrix theory for signal processing applications is however scarce and highly technical. This tutorial proposes an ...

2011-01-01

149

Negative regulation of {beta}-catenin/Tcf signaling by naringenin in AGS gastric cancer cell  

Science.gov (United States)

Functional activation of {beta}-catenin/Tcf signaling plays an important role in early events in carcinogenesis. We examined the effect of naringenin against {beta}-catenin/Tcf signaling in gastric cancer cells. Reporter gene assay showed that naringenin inhibited {beta}-catenin/Tcf signaling efficiently. In addition, the inhibition of {beta}-catenin/Tcf signaling by naringenin in HEK293 cells transiently transfected with constitutively mutant {beta}-catenin gene, whose product is not phosphorylated by GSK3{beta}, indicates that its inhibitory mechanism was related to {beta}-catenin itself or downstream components. To investigate the precise inhibitory mechanism, we performed immunofluorescence, Western blot, and EMSA. As a result, our data revealed that the {beta}-catenin distribution and the levels of nuclear {beta}-catenin and Tcf-4 proteins were unchanged after naringenin treatment. Moreover, the ...

2005-09-30

150

MRI with pathogenic correlation of small renal cell carcinoma  

Energy Technology Data Exchange (ETDEWEB)

MRI, ultrasonography and angiography were performed on 24 cases with small renal cell carcinoma, and data were compared with pathological architecture type. An average diameter of cancer was 20.8 mm (10-30 mm). Each tumor was pathologically classified into four architecture types: alveolar type (15 cases), papillary type (5 cases), tubular type (3 cases) and cystic type (1 case). In comparison with renal cortex alveolar type renal cell carcinoma showed equal or low signal in T1-weighted images and equal or high signal in T2-weighted images. Papillary and tubular types showed high signal in T1-weighted images, and low signal in T2-weighted images. In alveolar type, many cases showed equal echo in ultrasonography and hypervascularity in angiography, and in papillary and tubular types, many cases showed high echo and hypovascularity. There were many cases with papillary type small cell carcinoma which ...

1999-11-01

151

Effect of Wnt-1 inducible signaling pathway protein-2 (WISP-2/CCN5), a downstream protein of Wnt signaling, on adipocyte differentiation  

British Library Electronic Table of Contents (United Kingdom)

Wnt signaling negatively regulates adipocyte differentiation, and ectopic expression of Wnt-1 in 3T3-L1 cells induces several downstream molecules of Wnt signaling, including Wnt-1 inducible signaling pathway protein (WISP)-2. In this study, we examined the role of WISP-2 in the process of adipocyte differentiation using an in vitro cell culture system. In the differentiation of 3T3-L1 cells, WISP-2 expression was observed in growing cells and declined thereafter. In the mitotic clonal expansion phase of adipocyte differentiation, WISP-2 expression was transiently down-regulated concurrently with up-regulation of CCAAT/enhancer-binding protein d expression. Treatment of 3T3-L1 cells in the differentiation medium with lithium, an activator of Wnt signaling, inhibited the differentiation pro...

2009-01-01

152

Comparative experimental study of dual energy subtraction and conventional digital radiography on chest  

International Nuclear Information System (INIS)

Objective: To compare the efficiency of dual energy subtraction and conventional direct digital radiography in signal detecting ability. Methods: 200 plastic balls which were 4 mm in diameter were taken as signals and were placed on a 10 cm thick plastic board and the right upper thorax of a healthy volunteer. The signals were examined by DES and CDR separately and were estimated by 3 radiologists with 5-value-differentiation method. ROC curve analysis was made by ROC kit software. Results: when signals on plastic board were detected by CDR and DES, ROC curve analysis indicated that there was no significant difference (P=0.4851 > 0.05, two-tailed) between the area under the ROC curves of the two methods (Az=0.9931 for CDR and Az=0.9879 for DES). The difference was significant (P=0.0002 <0.01, two-tailed) between the area under the ROC curves of CDR and DES (Az=0.7276 for CDR and Az=0.8561 for ...

2005-06-01

153

Blind source separation of convolutive mixtures of non circular linearly modulated signals with unknown baud rates  

CERN Document Server

This paper addresses the problem of blind separation of convolutive mixtures of BPSK and circular linearly modulated signals with unknown (and possibly different) baud rates and carrier frequencies. In previous works, we established that the Constant Modulus Algorithm (CMA) is able to extract a source from a convolutive mixture of circular linearly modulated signals. We extend the analysis of the extraction capabilities of the CMA when the mixing also contains BPSK signals. We prove that if the various source signals do not share any non zero cyclic frequency nor any non conjugate cyclic frequencies, the local minima of the constant modulus cost function are separating filters. Unfortunately, the minimization of the Godard cost function generally fails when considering BPSK signals that have the same rates and the same carrier frequencies. This failure is due to the existence of ...

2011-01-01

154

Traffic signal control for a multi-forked road  

British Library Electronic Table of Contents (United Kingdom)

Traffic jams have become very serious at multiforked road intersections, and conventional pre-timed controls are less effective in such situations. In this article, a new traffic signal control system for multi-forked roads is proposed. First, the cellular automaton (CA) model is used to develop a traffic simulator for multi-forked roads. Next, a stochastic model of a traffic jam is built up. In addition, a new traffic signal control algorithm is designed using the optimization technique and a genetic algorithm (GA). Finally, the effectiveness of the proposed method is shown using actual traffic data with a traffic simulator.

2011-01-01

155

Signal simulator for the calibration of eddy current probes  

Energy Technology Data Exchange (ETDEWEB)

This paper describes a signal simulator which is designed to calibrate eddy current probes. By using simultaneously an excitation coil and an electrically conducting plane, the simulator can emulate signals which correspond to spot welds with different flaws. The presence of a conducting plane allows a wide variation of the amplitude and phase of the excitation coil voltage during the calibration of a probe. A mathematical model for the simulator is derived and used to study the variation of the impedance change upon the parameters of the probe. Numerical computation shows that the impedance change depends in an important way on the frequency of the excitation coil current.

1994-01-01

156

Ruling out a 4th generation using limits on hadron collider Higgs signals  

CERN Document Server

We consider the impact of a 4th generation on Higgs to $\\gamma\\gamma$ and $WW,ZZ$ signals and demonstrate that the Tevatron and LHC have essentially eliminated the possibility of a 4th generation if the Higgs is SM-like and has mass below 200 GeV. We also show that the absence of enhanced Higgs signals in current data sets in the $\\gamma\\gamma$ and $WW,ZZ$ final states can strongly constrain (almost eliminate) the possibility of a 4th generation in two-Higgs-doublet models of type II (in the MSSM).

2011-01-01

157

Preparatory Signal Detection for Annex I Countries under the Kyoto Protocol. A Lesson for the Post-Kyoto Policy Process  

Energy Technology Data Exchange (ETDEWEB)

The focus of this study is on the preparatory detection of uncertain net greenhouse gas (GHG) emission changes (also termed emission signals) under the Kyoto Protocol. The crucial question to be addressed is: How well do we need to know net emissions if we want to detect a specified emission signal after a given time? No restrictions exist as to what concerns the net emitter, which may be any GHG source or sink. Annex I countries are chosen as net emitters, simply for reasons of data availability and because of the excellent possibility of comparing net emitters (inter-country comparison). The countries' emissions - in an increasing number of cases even their uncertainties - are available permitting the application of preparatory signal detection techniques, which are suited to address the aforementioned question. We currently discuss four hierarchically-ordered detection concepts to assess emission ...

2004-06-14

158

Phenomenological study of light-induced effects in #alpha#-Al_2O_3:C  

International Nuclear Information System (INIS)

A computerised glow curve deconvolution (CGCD) analysis was applied to the main dosimetric peak of #alpha#-Al_2O_3:C in order to study the effects of light on the glow curve shape. It was shown that both the light-induced signal and the light-induced fading effects tend to shift the main dosimetric peak to higher temperatures and at the same time change its shape. Furthermore it was confirmed that the magnitude of the light-induced signal depends on radiation history and, by increasing the duration of light exposure, the magnitude of the light-induced signal reaches a plateau, thereby implying the saturation of the phototransfer process. (author).

1995-07-10

159

Nutrition and Physical Activity in Aging, Obesity, and Cancer  

British Library Electronic Table of Contents (United Kingdom)

The liver is a primary target of growth hormone (GH). GH signals are mediated by the transcription factor signal transducer and activator of transcription 5 (STAT5). Here, we focus on recent discoveries about the role of GH-STAT5 signaling in hepatic physiology and pathophysiology. We discuss roles of the GH-STAT5 axis in body growth, lipid metabolism, and the cell cycle pertaining to hepatosteatosis, fibrosis, and hepatocellular carcinoma. Finally, we discuss recent discoveries about the role of GH-STAT5 in sex-specific gene expression and bile acid, steroid, and drug metabolism.

2011-01-01

160

Confocal Imaging of Biological Tissues Using Second Harmonic Generation  

Energy Technology Data Exchange (ETDEWEB)

A confocal microscopy imaging system was devised to selectively detect Second harmonic signals generated by biological tissues. Several types of biological tissues were examined using this imaging system, including human teeth, bovine blood vessels, and chicken skin. All these tissues generated strong second harmonic signals. There is considerable evidence that the source of these signals in tissue is collagen. Collagen, the predominant component of most tissues, is known to have second order nonlinear susceptibility. This technique may have diagnostic usefulness in pathophysiological conditions characterized by changes in collagen structure including malignant transformation of nevi, progression of diabetic complications, and abnormalities in wound healing.

2000-03-06

161

Time Integrating Optical Signal Processing  

Science.gov (United States)

... The acousto-optic device have a 30 MHz 1 ... coherent systems including compact non-coherent optical ... a relatively simple phase switching approach. ...

1981-07-01

162

The mass dependence of the signal peak height of a Bragg-curve ionization chamber  

International Nuclear Information System (INIS)

The Bragg-curve detector of the parallel plate ionization chamber type generates a signal that is a distorted replica of the original Bragg-curve. In result of this distortion, the signal peak height is not only a function of the atomic number of the heavy ion, as it is often stated, but also of the particle mass. This mass effect was studied with the aid of computer simulation, and it was found to be dependent on the Frisch grid to anode gap width and on the detector gas. The charge resolution of the detector is affected very significantly by this mass dependence of the signal peak height. Therefore, a careful selection of the detector gas and the grid to anode gap width is necessary, if good charge resolution over a wide range of heavy ions is required. (orig.).

163

The androgen receptor governs the execution, but not programming, of male sexual and territorial behaviors  

UK PubMed Central (United Kingdom)

SUMMARYTestosterone and estrogen are essential for male behaviors in vertebrates. How these two signaling pathways interact to control masculinization of the brain and behavior...Full Text Available

2010-04-29

164

The Natural Statistics of Audiovisual Speech  

UK PubMed Central (United Kingdom)

Humans, like other animals, are exposed to a continuous stream of signals, which are dynamic, multimodal, extended, and time varying in nature. This complex input space must be transduced and sampled...Full Text Available

2009-07-01

165

Telomeres and telomerase in cancer  

UK PubMed Central (United Kingdom)

Myriad genetic and epigenetic alterations are required to drive normal cells toward malignant transformation. These somatic events commandeer many signaling pathways that cooperate to endow aspiring...Full Text Available

2010-01-01

166

Superterrorism and the Military Instrument of Power  

Science.gov (United States)

... Defense. ... 6 Specific restrictions are outlined in US Signals Intelligence Directive (USSID) 18 and DoD Regulation 5240.1-R. 7 House ...

1998-04-01

167

Strings, tachyons and deconfinement  

Energy Technology Data Exchange (ETDEWEB)

We argue that the tachyons which exist in some string models are a signal of deconfinement. We compare the deconfinement temperature obtained from Monte Carlo calculations with some string models. (orig.).

1985-10-17

168

Strings, tachyons and deconfinement  

International Nuclear Information System (INIS)

We argue that the tachyons which exist in some string models are a signal of deconfinement. We compare the deconfinement temperature obtained from Monte Carlo calculations with some string models. (orig.).

169

Retinoids for Treatment of Retinal Diseases  

UK PubMed Central (United Kingdom)

Knowledge about retinal photoreceptor signal transduction and the visual cycle required for normal eyesight has expanded exponentially over the past decade. Substantial progress in human genetics...Full Text Available

2010-06-01

170

R/V Laurence M. Gould LMG0303 - Development of a luminescence - NASA  

Science.gov (United States)

R/V Laurence M. Gould LMG0303 - Development of a luminescence dating capability for Antarctic glaciomarine sediments: Tests of signal zeroing at the ...

171

Polymer Genomics: An Insight into Pharmacology and Toxicology of Nanomedicines 1  

UK PubMed Central (United Kingdom)

Synthetic polymers and nanomaterials display selective phenotypic effects in cells and in the body that affect signal transduction mechanisms involved in inflammation, differentiation, proliferation,...Full Text Available

2006-12-30

172

Photonic Devices and Systems for Optical Signal Processing  

Science.gov (United States)

... lasers, model switched optical memory elements ... Optical RS flip flop, Acousto-optic switches. ... FLOP CIRCUITS, OPTICAL SWITCHING, NOR GATES ...

1993-08-01

173

Performance Evaluation of Several Types of Pulsed Eddy Current Probes for Detecting Wall Thickness Reduction  

Science.gov (United States)

In this paper, four different types of pulsed eddy current (PEC) probe are designed and their performance of detecting wall thickness reduction is compared. By using the backward difference method in time and the finite element method in space, PEC signals from various thickness and materials are numerically calculated and three features of the signal are selected. Since PEC signals and features are obtained by various types and sizes of probe, the comparison is made through the normalized features which reflect the sensitivity of the feature to thickness reduction. The normalized features indicate that the shielded reflection probe provides the best sensitivity to wall thickness reduction for all three signal features. Results show that the best sensitivity to thickness reduction is achieved by the peak value, but also suggest that the time to peak can be a good candidate because of its linear ...

2010-02-01

174

Optical dating: insufficiently bleached sediments  

International Nuclear Information System (INIS)

Although infrared-stimulated luminescence (IRSL) signals in feldspars can be bleached rapidly by sunlight, there could still be a small amount of IRSL signal remaining in sediment grains if they have experienced only relatively short sunlight exposure before deposition. This remaining signal results in a ''remnant dose'' stored in the grain and is important for young samples but negligible for old samples. Several methods have been introduced to detect insufficient bleaching, and some of them can provide information on the extent of the bleaching. Others can only distinguish between samples bleached for a very long time and for a short time. Empirical methods are introduced to evaluate the possible values of equivalent dose accumulated since the grains were deposited. These methods involve the analysis of the equivalent doses and the natural IRSL signals obtained using single-disc dose determination ...

1993-07-01

175

Optical Processing of Microwave Signals - Part B  

Science.gov (United States)

... switching off all the pixels causes all the spectrum lines to disappear (top of Figure 6), next, that switching off one ... Acousto-optic spectrum analyser ...

2003-04-01

176

On the spontaneous emergence of cell polarity  

UK PubMed Central (United Kingdom)

Diverse cell polarity networks require positive feedback for locally amplifying distributions of signalling molecules at the plasma membrane1. Additional...Full Text Available

2008-08-14

177

Neural processing of asynchronous audiovisual speech perception  

UK PubMed Central (United Kingdom)

The temporal synchrony of auditory and visual signals is known to affect the perception of an external event, yet it is unclear what neural mechanisms underlie the influence of temporal synchrony...Full Text Available

2010-02-15

178

N92-22051  

Science.gov (United States)

The KDP crystal was 10 cm long and cut such that the c-axis was 50.3* to the normal of its input face. We selected for study idler and signal beams ...

179

Medium voltage analytical electron microscopy microanalysis versus radiation damage  

Energy Technology Data Exchange (ETDEWEB)

The kinetic energy transferred to some elements by an electron of kinetic energy 100 to 400 kV is discussed. The displacement rates are compared to the signal generation. (DCL)

1985-09-01

181

Mass dependence of the signal peak height of a Bragg-curve ionization chamber  

Energy Technology Data Exchange (ETDEWEB)

The Bragg-curve detector of the parallel plate ionization chamber type generates a signal that is a distorted replica of the original Bragg-curve. In result of this distortion, the signal peak height is not only a function of the atomic number of the heavy ion, as it is often stated, but also of the particle mass. This mass effect was studied with the aid of computer simulation, and it was found to be dependent on the Frisch grid to anode gap width and on the detector gas. The charge resolution of the detector is affected very significantly by this mass dependence of the signal peak height. Therefore, a careful selection of the detector gas and the grid to anode gap width is necessary, if good charge resolution over a wide range of heavy ions is required.

1985-01-01

182

Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung  

British Library Electronic Table of Contents (United Kingdom)

Fibroblast growth factor (FGF) signaling has been shown to regulate lung epithelial development but its influence on mesenchymal differentiation has been poorly investigated. To study the role of mesenchymal FGF signaling in the differentiation of the mesenchyme and its impact on epithelial morphogenesis, we took advantage of Fgfr2c+/? mice, which due to a splicing switch express Fgfr2b in mesenchymal tissues and manifest Apert syndrome-like phenotypes. Using a set of in vivo and in vitro studies, we show that an autocrine FGF10?FGFR2b signaling loop is established in the mutant lung mesenchyme, which has several consequences. It prevents the entry of the smooth muscle progenitors into the smooth muscle cell (SMC) lineage and results in reduced fibronectin and elastin deposition. Levels of...

2006-01-01

183

Infrared bleaching of the thermoluminescence of four feldspars  

International Nuclear Information System (INIS)

This paper studies the effect upon the thermoluminescence (TL) signal of four feldspar samples of exposing them to infrared stimulation, as occurs during infrared-stimulated luminescence (IRSL) measurement. Together with pulse annealing measurements these results are used to show which part of the TL signal is removed by exposure to IR and which part is directly related to the IRSL signal that is observed. When the samples are preheated prior to measurement in order to remove any low-temperature (< 200"oC) TL signals, a linear relationship is observed between the amount of TL that is lost and the IRSL light sum that is produced. The IRSL light sum is consistently four times larger than the amount of TL that is lost. Three possible explanations are proposed for this, but no conclusive evidence could be obtained to support any of them. A close similarity is observed in the pulse annealing results and ...

1995-06-01

184

History of the Army Ground Forces. Study Number 13. ...  

Science.gov (United States)

... reconnaissance. Presently the signal ompWa captain rushed up, salutec snappily, anI reported. When the general inquired how. ...

1948-06-30

185

Genomics of human longevity  

UK PubMed Central (United Kingdom)

In animal models, single-gene mutations in genes involved in insulin/IGF and target of rapamycin signalling pathways extend lifespan to a considerable extent. The genetic, genomic and epigenetic influences...Full Text Available

2011-01-12

186

Effect of COX-2 (PGE2) and IL-6 on Prostate Cancer Bone ...  

Science.gov (United States)

... of the AR (25). Dihydrotestosterone increases Wnt signaling activity in preosteoblasts. Functional interactions between ...

2008-02-02

187

ESR dating of fault rocks  

Energy Technology Data Exchange (ETDEWEB)

Past movement on faults can be dated by measurement of the intensity of ESR signals in quartz. These signals are reset by local lattice deformation and local frictional heating on grain contacts at the time of fault movement. The ESR signals then trow back as a result of bombardment by ionizing radiation from surrounding rocks. The age is obtained from the ratio of the equivalent dose, needed to produce the observed signal, to the dose rate. Fine grains are more completely reset during faulting, and a plot of age vs grain size shows a plateau for grains below critical size : these grains are presumed to have been completely zeroed by the last fault activity. We carried out ESR dating of fault rocks collected from the Yangsan fault system. ESR dates from the this fault system range from 870 to 240 ka. Results of this research suggest that long-term cyclic fault activity continued into the pleistocene.

2002-03-15

188

Dysregulation of the mevalonate pathway promotes transformation  

UK PubMed Central (United Kingdom)

The importance of cancer metabolism has been appreciated for many years, but the intricacies of how metabolic pathways interconnect with oncogenic signaling are not fully understood. With a clear understanding...Full Text Available

2010-08-24

189

Digital Hearing Aids: Current "State-of-the-Art"  

Science.gov (United States)

... promise of highly advanced signal processing, ensured that digital hearing aid technology had come of age. So how far have ...

190

Digital Audio Sampling for Film and Video.  

Science.gov (United States)

Digital audio sampling is explained, and some of its implications in digital sound applications are discussed. Digital sound equipment is rapidly replacing analog recording devices as the state-of-the-art in audio technology. The philosophy of digital recording involves doing away with the continuously variable analog waveforms and turning the patterns into numbers. A digital recording device rapidly samples the incoming sounds, quantifying the signal into a series of numerical values (binary codes). Although digital sound eliminates many of the traditional analog problems, digital signal processing presents key problems in sampling rates and synchronization. Careful control is necessary to check signals through each step in the audio chain. The advantages of digital audio processing include increased signal-to-noise ratio, no flutter, transparent generation of copies, and sound manipulation. These ...

1993-03-01

191

Composite vector leptoquarks in [ital e][sup +][ital e[minus  

Energy Technology Data Exchange (ETDEWEB)

We study the signals for composite vector leptoquarks in [ital e][sup +][ital e[minus

1993-02-01

192

Chimpanzees Extract Social Information from Agonistic Screams  

UK PubMed Central (United Kingdom)

Chimpanzee (Pan troglodytes) agonistic screams are graded vocal signals that are produced in a context-specific manner. Screams given by aggressors and victims can be discriminated...Full Text Available

193

Center for Advanced Sensors Year Two Funding (FY2006)  

Science.gov (United States)

... a Networked Embedded Sensing Toolkit (MSR Sense ... edging due to mis-registration than the ... Langrebe, Signal theory in multisensor remote sensing ...

2008-02-26

194

CAAX-box protein, prenylation process and carcinogenesis  

UK PubMed Central (United Kingdom)

CAAX proteins are widely involved in global cellular functions such as proliferation, differentiation, and carcinogenesis. As an important modulator of biological activity, signal transduction via protein...Full Text Available

195

Bacterial chemoreceptors: high-performance signaling in networked arrays  

UK PubMed Central (United Kingdom)

Chemoreceptors are crucial components in the bacterial sensory systems that mediate chemotaxis. Chemotactic responses exhibit exquisite sensitivity, extensive dynamic range and precise adaptation....Full Text Available

2008-01-01

196

Army Communicator. Volume 32, Number 2, Spring 2007  

Science.gov (United States)

... Introduction to the Signal Regiment Cisco Academy 1-4 (CCNA) Engineering Math Basic Electronics/Digital Logic (replaced C Programming ...

2011-05-14

197

An Extended Kalman Filter for Use in a Shared Aperture ...  

Science.gov (United States)

... used to track a point source target ... A one sigma tracking error of .2 ... LOOKING INFRARED SYSTEMS, *KALMAN FILTERING, SIGNAL PROCESSING ...

1978-12-01

198

Advanced readout integrated circuit signal processing  

Science.gov (United States)

Readout integrated circuits (ROICs) for focal plane arrays (FPAs) have become increasingly complex to meet the needs of modern infrared systems. BAE Systems has pioneered a number of advanced signal processing architectures for FPA ROICs. Demonstrated signal processing capabilities of BAE Systems FPAs include analog-to-digital conversion, offset subtraction, individual pixel automatic gain compensation, transient noise suppression, on-FPA defect deselection, reconfigurable pixels, spatial neural network processing and subframe noise averaging. BAE Systems FPA advanced signal processing is not just for demonstrations, but is used in many of their deliverable FPAs, improving real system performance.

2006-06-01

199

A wavelet approach to fault diagnosis of a gearbox under varying load conditions  

British Library Electronic Table of Contents (United Kingdom)

Varying load can cause changes in a measured gearbox vibration signal. However, conventional techniques for fault diagnosis are based on the assumption that changes in vibration signal are only caused by deterioration of the gearbox. There is a need to develop a technique to provide accurate state indicator of gearbox under fluctuating load conditions. This paper presents an approach to gear fault diagnosis based on complex Morlet continuous wavelet transform under this condition. Gear motion residual signal, which represents the departure of time synchronously averaged signal from the average tooth-meshing vibration, is analyzed as source data due to its lower sensitiveness to the alternating load condition. A fault growth parameter based on the amplitude of wavelet transform is proposed ...

2010-01-01

200

A program for passively tracking a target using an array of sensors  

Energy Technology Data Exchange (ETDEWEB)

The problem of passively tracking a moving signal source has importance in a variety of applications such as radar, sonar, seismology, and radio astronomy. In many applications, only limited information is available about the signal source. It will be assumed here that only the signals which are detected by the sensors and the velocity of the source signal are known. The objective of this document is to present a program which passively tracks a target using an array of sensors. This program is available in MATLAB, version 3.5. The algorithm which is implemented consists of three main parts: time delay estimation, passive localization, and data post processing. Each of these parts are discussed, and the mathematical foundation for their solution given. Following, this the organization of the program is presented, and an example of its usage is given.

1993-01-01

202

Rainfall effect on single-vehicle crash severities using polychotomous response models.  

Science.gov (United States)

As part of the Wisconsin road weather safety initiative, the objective of this study is to assess the effects of rainfall on the severity of single-vehicle crashes on Wisconsin interstate highways utilizing polychotomous response models. Weather-related factors considered in this study include estimated rainfall intensity for 15 min prior to a crash occurrence, water film depth, temperature, wind speed/direction, stopping sight distance and deficiency of car-following distance at the crash moment. For locations with unknown weather information, data were interpolated using the inverse squared distance method. Non-weather factors such as road geometrics, traffic conditions, collision types, vehicle types, and driver and temporal attributes were also considered. Two types of polychotomous response models were compared: ordinal logistic and sequential logistic regressions. The sequential logistic regression was tested with forward and backward formats. Comparative models were also ...

2009-08-14

203

Geotechnical treatment of generated soil and wastes, and their effective use. Burial of wastes and use of thus-formed sites; Hasseido oyobi haikibutsu no jiban kogakuteki shori to yuko riyo. Haikibutsu no umetate to atochi riyo  

Energy Technology Data Exchange (ETDEWEB)

To use such sites very effectively, pile foundations will be used for soil stabilization and for important structures for the prevention of subsidence. Negative friction that may ensue from the differential settlement of the soil has to be prevented. Measures against gas will include gas collecting and exhausting facilities in the lower parts of structures, natural and forced exhaust systems, and gas detection/warning units. For revegetation, plants strong against bad soil should be selected, they should be protected from generated gas with protecting sheets or the like, and a thick layer of vegetation-capable soil needs to be laid. Replacement, compaction, and solidification are the fundamentals of soil improvement at wastes final treatment locations and of soil-related pollution prevention in the vicinity of the newly produced sites. Across the country, the service life expectancy is approximately 7-8 years for general wastes and approximately 2.3 years for ...

1997-09-01

204

Appendix W: deep sea biophysics (microbiology and amphiped studies)  

International Nuclear Information System (INIS)

CNPT-3 is the laboratory designation of a strain of bacteria that reproduces best at deep-sea pressures. It was isolated from a sample collected at a 5800 m depth of the Pacific Ocean. This isolation was achieved from a sample that had been retrieved without warning. This year we demonstrated that there are similarly behaving bacteria that can be isolated from samples even when retrieved with decompression. The purpose of this project was to define the temperatures and pressures over which CNPT-3 can exist and function. (1) At 2"0C CNPT-3 is eurybathic from about 1000 to 6500 m, as judged from an only slightly pressure dependent generation time. (2) CNPT-3 is unquestionably barophilic at 2"0C, with doubling times of 9 hours at 580 bars and over 18 hours at 1 bar. (3) At 10"0C, reproduction is adversely affected at 1 bar to the extent that CNPT-3 becomes obligately barophilic at 10"0C. Yet reproduction is enhanced above 280 bars and occurs with a regeneration time ...

1981-04-01

205

Use of signal delay of one of detectors in two-channel radiometric flaw detector  

International Nuclear Information System (INIS)

A possibility is considered or reducing the surface heterogeneity effect of an item being tested on the result of radiation flaw detection by means of signal delay of one of detectors in a two-channel radiometric flaw detector. The exposure of a translationally moving item has been studied as well as an external exposure of a rotating hollow item.

206

Up-Regulation of the RhoA/Rho-Kinase Signaling Pathway in Corpus Cavernosum from Endothelial Nitric-Oxide Synthase (NOS), but Not Neuronal NOS, Null Mice  

UK PubMed Central (United Kingdom)

We tested the hypothesis that the basal release of nitric oxide (NO) from endothelial cells modulates contractile activity in the corpus cavernosum (CC) via inhibition of the RhoA/Rho-kinase signaling...Full Text Available

2010-04-01

207

The analysis of coupled heat and particle transport in Tokamaks by means of Fourier transform  

Energy Technology Data Exchange (ETDEWEB)

A method to deduce the 2 x 2 transport matrix for coupled heat and particle transport in Tokamaks is proposed. The method applies to perturbative experiments, and is based on a Fourier transform of the measured signals of temperature and density. By analyzing different linear combinations of temperature and density, the eigenvectors and eigenvalues of the transport matrix are determined. The method is tested for a number of illustrative cases using simulated data, and the sensitivity to noise on the signals is evaluated. (author).

1992-04-01

208

The Cause of an Eddy Current Signal Noise from a Steam Generator Tube and its Effect on the Detectability of a Crack  

International Nuclear Information System (INIS)

An eddy current inspection has been applied for a pre-service and in-service examination of a steam generator in nuclear power plants. The experience from the inspection of steam generators showed that many plants had an excessive number of tubes with eddy current noise signals over several hundreds, which originated from manufacturing anomalies. The plants in U.S suffered significant downstream inspection costs, history reviews, and diagnostic testing because some signals resembled flaws and others masked a flaw. These lessens learned resulted in issuing the guidelines for steam generator tubing specifications and repair, in order to reduce the number of anomalous signals in the tubes and also to provide the requirement of a signal to noise ratio by applying a field type examination with bobbin coil eddy current probes at a manufacturing process. Besides the noise signals of a ...

2008-05-01

209

Strong WW scattering at photon linear colliders  

Energy Technology Data Exchange (ETDEWEB)

We investigate the possibility of observing strong interactions of longitudinally polarized weak vector bosons in the process {gamma}{gamma}{yields}ZZ at a photon linear collider. We make use of polarization of the photon beams and cuts on the decay products of the Z bosons to enhance the signal relative to the background of transversely polarized ZZ pairs. We find that the background overwhelms the signal unless there are strong resonant effects, as for instance from a technicolor analogue of the hadronic f{sub 2}(1270) meson. ((orig.)).

1995-02-01

210

Strong WW scattering at photon linear colliders  

Energy Technology Data Exchange (ETDEWEB)

We investigate the possibility of observing strong interactions of longitudinally polarized weak vector bosons in the process {gamma}{gamma} {yields} ZZ at a photon linear collider. We make use of polarization of the photon beams and cuts on the decay products of the Z bosons to enhance the signal relative to the background of transversely polarized ZZ pairs. We find that the background overwhelms the signal unless there are strong resonant effects, as for instance from a technicolor analogue of the hadronic f{sub 2}(1270) meson.

1994-06-01

211

Signal transduction pathway controlling synthesis of a class of degradative enzymes in Bacillus subtilis: expression of the regulatory genes and analysis of mutations in degS and degU.  

UK PubMed Central (United Kingdom)

The rates of synthesis of a class of both secreted and intracellular degradative enzymes in Bacillus subtilis are controlled by a signal transduction pathway defined by at least four regulatory genes:...Full Text Available

1990-02-01

212

Roles of the TNF receptor-associated factor (TRAF)2/3 binding site in differential B cell signaling by CD40 and its viral oncogenic mimic, latent membrane protein 1 (LMP1)  

UK PubMed Central (United Kingdom)

The Epstein-Barr virus protein, LMP1, is a functional mimic of the cellular receptor CD40, but signals to B lymphocytes in an amplified and sustained manner compared to CD40. LMP1 contributes...Full Text Available

2009-09-01

213

Real-time monitoring of dosimetry and image quality during digital radiology examinations  

International Nuclear Information System (INIS)

Objective: To explore the feasibility of real-time monitoring exposure dose and image quality by using the data stored in the DICOM image archive of direct digital radiography system. Methods: Model TO. 16 was exposed, the current increased gradually from 0.5 to 125 mAs. The displayed number of model A( diameter 11.1 mm), D (diameter 4.0 mm) and J( diameter 0.7 mm) were recorded, and the detect factors (H_T) was also calculated. Images were sent to workstation before the end of DR examination. An automatic procedure was implemented to extract dose data and exposure parameters from the DICOM header file. Maximum, minimum and 3rd quartile values were preinstalled. Mean values exceeding the threshold trigger alarm signal to guide radiologist to explore the cause. Results: When the current of point A was less than 10 mAs and the current of point D and J were less than 16 mAs, the detect factor (H_T) increased with the rise of current. While point A located within ...

2009-12-01

214

Real time control of micro-machine system using micro-computer based fuzzy logic power system stabilizer  

Energy Technology Data Exchange (ETDEWEB)

A micro-computer based fuzzy logic power system stabilizer is applied to a micro-machine system to investigate its efficiency in real time control. The stabilizing signal is determined by using measured speed or real power signals at every sampling time to damp the system oscillations. The results show the proposed stabilizer improves the system damping effectively subject to various types of disturbances.

1994-12-01

215

Prostaglandin E2 Signals Through PTGER2 to Regulate Sclerostin Expression  

UK PubMed Central (United Kingdom)

The Wnt signaling pathway is a robust regulator of skeletal homeostasis. Gain-of-function mutations promote high bone mass, whereas loss of Lrp5 or Lrp6 co-receptors decrease bone mass. Similarly, mutations...Full Text Available

216

Method of controlling the coolant level in the cooling system of a nuclear power plant  

International Nuclear Information System (INIS)

Object: To prevent a sudden drop in the level of a coolant in a annular pipe encased within a downcomer pipe. Structure: The coolant levels in annular pipes encased within downcomer pipes are simultaneously measured by level gauges which generate signals representative of coolant levels. The signals are fed to a level control system which will actuate valves to regulate the cover gas pressure in order to average the level differences among the annular pipes in different downcomer pipes. (Kamimura, M.).

217

Long-range correlation analysis of earthquake-related geochemical variations recorded in Central Italy  

Energy Technology Data Exchange (ETDEWEB)

The long-range correlation properties in the hourly time variability of geochemical signals measured in a 70 m depth well at Triponzo (Umbria region), are investigated by the detrended fluctuation analysis (DFA). DFA is a data processing method that allows for the detection of scaling behaviors in observational time series even in the presence of non-stationarities. The procedure adopted has allowed for the unambiguous identification of possible correlations among the recorded signals and local earthquakes.

2004-07-01

218

Infrared-stimulated luminescence dating of sediments  

Energy Technology Data Exchange (ETDEWEB)

Luminescence stimulated from feldspars using wavelengths in the infrared region can be applied to the dating of sedimentary grains. Reported stimulation spectra are very similar for a wide range of feldspars, but their emission spectra show greater variation. For accurate dating it is critical that unstable infrared-stimulated luminescence (IRSL) signals are removed from the laboratory-irradiated grains. Several approaches to isolate a thermally stable signal are described. (author).

1994-04-01

219

Implementation and laboratory test results for a fuzzy logic based self-tuned power system stabilizer  

Energy Technology Data Exchange (ETDEWEB)

This paper describes the implementations of a fuzzy logic based self-tuned controller to improve the stability of electric power systems. The stabilizing signal is computed using the standard fuzzy membership function depending on the speed/acceleration state of the generator in the phase plane. The performance of the proposed stabilizer is demonstrated by practical implementation using a digital signal processor mounted on a PC-AT. Results of the experimental tests on a physical model of a power system are presented.

1993-06-01

220

Gas-diesel dual fuel engine  

Energy Technology Data Exchange (ETDEWEB)

A gas-diesel dual fuel engine apparatus is described having a diesel engine, a diesel fuel supply system including a diesel fuel injection pump, a gaseous fuel supply system including a gaseous fuel regulating valve, and a governing and controlling device for governing the speed of the engine through the control of fuel supplied to the engine and controlling the switchover of the operation of the engine between a diesel fuel mode and a gaseous fuel mode. The improvement of the governing and controlling device consists of: (a) at least one electronic governor means adapted to compare a speed signal representing the actual operating speed of the diesel engine with a set speed signal representing the set speed thereof; (b) a pair of electric actuator means having respective power amplifier circuits and mechanically connected to the diesel fuel injection pump and the gaseous fuel regulating valve, respectively, for the actuation thereof; (c) mode ...

1986-03-18

221

Feasibility of FIR laser stabilization by injection of a synthesized signal  

Energy Technology Data Exchange (ETDEWEB)

In this paper the feasibility of phase locking a FIR laser by injection of a highly stable synthesized signal is examined. The theory of injection locking is revised in order to take into account the characteristic features of FIR lasers and turns out to be in satisfactory agreement with the experimental data reported. From the results obtained, it is inferred that the state of the art of submillimetric multipliers makes it possible to stabilize FIR laser emissions up to about 1 THz.

1980-12-01

222

Digital signal processing for beam position feedback  

Energy Technology Data Exchange (ETDEWEB)

Stabilization of the particle beam position with respect to the focusing optics in the third generation synchrotron light sources is crucial to achieving low emittance and high brightness. For this purpose, global and local beam orbit correction feedbacks will be implemented in the APS storage ring. In this article, the authors discuss application of digital signal processing to particle/photon beam position feedback using the PID (proportional, integral, and derivative) control algorithm.

1992-04-01

223

Differential regulation of the biosynthesis of glucose transporters by the PI3-K and MAPK pathways of insulin signaling by treatment with novel compounds from Liriope platyphylla.  

Science.gov (United States)

The insulin signaling pathway, involving protein kinase B (PKB) and mitogen-activated protein kinase (MAPK), mediates the biological response to insulin and several growth factors and cytokines. To investigate the correlation between glucose transporter (Glut) biosynthesis and the insulin signaling pathway activated by novel compounds of Liriope platyphylla (LP9M80-H), alterations in Glut and key protein expression in the insulin signaling pathway were analyzed in the liver and brain of ICR mice treated with LP9M80-H. An in vitro assay showed that the highest level of insulin concentration was observed in the LP9M80-H-treated group, followed by the LP-H, LP-M, LP-E, and LP9M80-C-treated groups. Therefore, LP9M80-H was selected for use in studying the detailed mechanism of the insulin signaling pathway in animal systems. In an in vivo experiment, LP9M80-H induced a significant increase in glucose levels ...

2010-12-14

224

Capacity analysis techniques for signalized intersections  

Energy Technology Data Exchange (ETDEWEB)

This book contains nomographs for analysis and design of signalized intersections and thoroughly explains how to use them. The nomographs simplify and reduce the work that otherwise would have to be done by hand. The nomograph method for computing capacity has a significant advantage over computerized methods: it provides insight into the interaction between the various factors in the solution process for design analysis.

1986-01-01

225

Amplified B Lymphocyte CD40 Signaling Drives Regulatory B10 Cell Expansion in Mice  

UK PubMed Central (United Kingdom)

BackgroundAberrant CD40 ligand (CD154) expression occurs on both T cells and B cells in human lupus patients, which is suggested to enhance B cell CD40 signaling and play a role...Full Text Available

226

(-)-Epigallocatechin Gallate Regulates CD3-mediated T Cell Receptor Signaling in Leukemia through the Inhibition of ZAP-70 Kinase*  

UK PubMed Central (United Kingdom)

The ζ chain-associated 70-kDa protein (ZAP-70) of tyrosine kinase plays a critical role in T cell receptor-mediated signal transduction and the immune response. A high level of ZAP-70 expression...Full Text Available

2008-10-17

227

Using support vector machines in the multivariate state estimation technique  

Energy Technology Data Exchange (ETDEWEB)

One approach to validate nuclear power plant (NPP) signals makes use of pattern recognition techniques. This approach often assumes that there is a set of signal prototypes that are continuously compared with the actual sensor signals. These signal prototypes are often computed based on empirical models with little or no knowledge about physical processes. A common problem of all data-based models is their limited ability to make predictions on the basis of available training data. Another problem is related to suboptimal training algorithms. Both of these potential shortcomings with conventional approaches to signal validation and sensor operability validation are successfully resolved by adopting a recently proposed learning paradigm called the support vector machine (SVM). The work presented here is a novel application of SVM for data-based modeling of system state variables in ...

1999-07-01

228

United States Geological Survey (USGS) FM cassette seismic-refraction recording system  

Energy Technology Data Exchange (ETDEWEB)

In this two chapter report, instrumentation used to collect seismic data is described. This data acquisition system has two parts: (1) portable anolog seismic recorders and related ``hand-held-testers`` (HHT) and (2) portable digitizing units. During the anolog recording process, ground motion is sensed by a 2-Hz vertical-component seismometer. The voltage output from the seismometer is split without amplification and sent to three parallel amplifier circuit boards. Each circuit board amplifiers the seismic signal in three stages and then frequency modulates the signal. Amplification at the last two stages can be set by the user. An internal precision clock signal is also frequency modulated. The three data carrier frequencies, the clock carrier frequency, and a tape-speed compensation carrier frequency are summed and recorded on a recorded on a cassette tape. During the digitizing process, the cassette tapes are played ...

1988-12-31

229

Unbiased cut selection for optimal upper limits in neutrino detectors the model rejection potential technique  

CERN Document Server

We present a method for optimising experimental cuts in order to place the strongest constraints (upper limits) on theoretical signal models. The method relies only on signal and background expectations derived from Monte-Carlo simulations, so no bias is introduced by looking at actual data, for instance by setting a limit based on expected signal above the ``last remaining data event.'' After discussing the concept of the ``average upper limit,'' based on the expectation from an ensemble of repeated experiments with no true signal, we show how the best model rejection potential is achieved by optimising the cuts to minimise the ratio of this ``average upper limit'' to the expected signal from the model. As an example, we use this technique to determine the limit sensitivity of kilometre scale neutrino detectors to extra-terrestrial neutrino fluxes from a variety of models, e.g. ...

2003-01-01

230

Ignition timing control apparatus for internal combustion engine  

Energy Technology Data Exchange (ETDEWEB)

An ignition timing control apparatus is described for an internal combustion engine having a reference ignition timing comprising: sensing means for sensing vibrations including knocks of the engine; knock signal deriving means for deriving knock signals from the output of the sensing means; correction magnitude determining means for determining from the knock signals derived by the knock signal deriving means of ignition timing correction magnitude for suppressing the occurrence of knock; displacement magnitude determining means for determining from at least one of an output of the knock signal deriving means and an output of the correction magnitude determining means as a displacement magnitude for the reference ignition timing corresponding to the octane rating of a fuel used in the engine; and ignition timing determining means for setting the reference ignition timing at an ...

1986-06-17

231

Higher order time-frequency analysis as a tool for health monitoring  

Energy Technology Data Exchange (ETDEWEB)

In machine condition monitoring many fault-related vibration signals are highly non-stationary. Time-frequency representations comprise the natural signal-processing tool traditionally used for representing such non-stationary signals. The methods used in this analysis are based on the second order statistics of a signal. This paper discusses the use of higher order time frequency methods in the context of a condition monitoring application. The paper outlines the two classes of higher order representations: the L-Wigner distribution and the sliced Wigner higher order distribution. The use of higher order distributions introduces the possibility of non-oscillating cross-terms, a problem not encountered in conventional bilinear time-frequency methods. Techniques for reducing these cross-terms are presented. The paper compares the performance of bilinear and higher order time-frequency methods using ...

2003-07-01

232

High field ESR of P-doped Si for Quantum Computing Application  

Energy Technology Data Exchange (ETDEWEB)

We measured ESR of phosphorous-doped silicon with a low concentration of P, n, at high magnetic fields and low temperatures to investigate the states of nuclear spin. A sample with n = 6.52 x 10{sup 16} /cm{sup 3} was studied at 2.85 T (80 GHz) from 30 K to 2.3 K by field-modulating cw-ESR for a fixed 0 dB power. As the temperature was lowered, the out-of-phase signal appeared around 18 K, reached at a maximum intensity at 13 K, and disappeared around 6 K. The out-of-phase signal is referred to the field modulation. The in-phase signal started to change from the derivative of absorption spectrum at high temperatures to absorption-like shape around 15 K and asymmetry of intensity for two peaks of hyperfine-separated signals increased as temperatures was lowered. Below 10 K, the saturation of the in-phase signal started to appear. We speculate that the asymmetry is caused by ...

2009-02-01

233

Global interrupt and barrier networks  

Energy Technology Data Exchange (ETDEWEB)

A system and method for generating global asynchronous signals in a computing structure. Particularly, a global interrupt and barrier network is implemented that implements logic for generating global interrupt and barrier signals for controlling global asynchronous operations performed by processing elements at selected processing nodes of a computing structure in accordance with a processing algorithm; and includes the physical interconnecting of the processing nodes for communicating the global interrupt and barrier signals to the elements via low-latency paths. The global asynchronous signals respectively initiate interrupt and barrier operations at the processing nodes at times selected for optimizing performance of the processing algorithms. In one embodiment, the global interrupt and barrier network is implemented in a scalable, massively parallel supercomputing device structure comprising a ...

2008-10-28

234

ESR dating of fault rocks  

Energy Technology Data Exchange (ETDEWEB)

Past movement on faults can be dated by measurement of the intensity of ESR signals in quartz. These signals are reset by local lattice deformation and local frictional heating on grain contacts at the time of fault movement. The ESR signals then grow back as a result of bombardment by ionizing radiation from surrounding rocks. The age is obtained from the ratio of the equivalent dose, needed to produce the observed signal, to the dose rate. Fine grains are more completely reset during faulting, and a plot of age vs. grain size shows a plateau for grains below critical size; these grains are presumed to have been completely zeroed by the last fault activity. We carried out ESR dating of fault rocks collected near the Gori nuclear reactor. Most of the ESR signals of fault rocks collected from the basement are saturated. This indicates that the last movement of the faults had occurred ...

2003-02-15

235

Coded Single-Tone Signaling for Resource Coordination and Interference Management in Femtocell Networks  

CERN Document Server

Resource coordination and interference management is the key to achieving the benefits of femtocell networks. Over-the-air signaling is one of the most effective means for distributed dynamic resource coordination and interference management. However, the design of this type of signal is challenging. In this letter, we address the challenges and propose an effective solution, referred to as coded single-tone signaling (STS). The proposed coded STS scheme possesses certain highly desirable properties, such as no dedicated resource requirement (no overhead), no near-and-far effect, no inter-signal interference (no multi-user interference), low peak-to-average power ratio (deep coverage). In addition, the proposed coded STS can fully exploit frequency diversity and provides a means for high quality wideband channel estimation. The coded STS design is demonstrated through a concrete numerical example. ...

2011-01-01

236

A wavelet approach to fault diagnosis of a gearbox under varying load conditions  

Science.gov (United States)

Varying load can cause changes in a measured gearbox vibration signal. However, conventional techniques for fault diagnosis are based on the assumption that changes in vibration signal are only caused by deterioration of the gearbox. There is a need to develop a technique to provide accurate state indicator of gearbox under fluctuating load conditions. This paper presents an approach to gear fault diagnosis based on complex Morlet continuous wavelet transform under this condition. Gear motion residual signal, which represents the departure of time synchronously averaged signal from the average tooth-meshing vibration, is analyzed as source data due to its lower sensitiveness to the alternating load condition. A fault growth parameter based on the amplitude of wavelet transform is proposed to evaluate gear fault advancement quantitatively. We found that this parameter is insensitive to varying load and ...

2010-04-01

237

A novel small-molecule inhibitor of NF-#kappa#B signaling  

International Nuclear Information System (INIS)

The inducible transcription factor NF-#kappa#B regulates divergent signaling pathways including inflammatory response and cancer development. Selective inhibitors for NF-#kappa#B signaling are potentially useful for treatment of inflammation and cancer. NF-#kappa#B is canonically activated by preferential disposal of its inhibitory protein; I#kappa#B, which suppresses the nuclear translocation of NF-#kappa#B. I#kappa#B#alpha# (a major member of I#kappa#B family proteins) is phosphorylated with an I#kappa#B kinase (IKK) and subsequently polyubiquitylated by SCF"#beta#"T"r"C"P"1 ubiquitin-ligase in the presence of E1 and E2 prior to proteasomal degradation. Here, we describe a novel inhibitor termed GS143, which suppressed I#kappa#B#alpha# ubiquitylation, but not I#kappa#B#alpha# phosphorylation, MDM2-directed p53 ubiquitylation, and proteasome activity in vitro. GS143 markedly suppressed the destruction of I#kappa#B#alpha# stimulated by ...

2008-04-18

238

Experimental study of lipiodol ultra-fluid. On its signal intensity in MR imaging  

Energy Technology Data Exchange (ETDEWEB)

Lipiodol Ultra-Fluid (Lipiodol) is widely applied in the transcatheter arterial embolization (TAE). We studied signal intensity, the T1 relaxation time and the T2 relaxation time of Lipiodol itself using Siemens Magnetom H15-2 T (1.5 Tesla) and Magnetom M10 (1.0 Tesla). Lipiodol showed higher signal intensity than saline solution on the T1-weighted images (short TR, short TE technique in spin echo method). On the T2-weighted images (long TR, long TE technique in spin echo method), Lipiodol showed lower signal intensity than saline solution. The T1 relaxation time of Lipiodol, measured at 1.0 T, was 201 msec and 218 msec at 1.5 T. The T2 relaxation time of Lipiodol, measured at 1.0 T, was 127 msec; and 167 msec at 1.5 T. The signal intensity of Lipiodol at 1.0 T was higher than the intensity at 1.5 T. Shorter T1 relaxation time of Lipiodol at 1.0 T is probably responsible for the higher intensity at 1.0 ...

1988-11-01

239

Equivalent dose estimation using a single aliquot of polymineral fine grains  

International Nuclear Information System (INIS)

We have tested the suitability of a new single-aliquot regenerative-dose protocol for estimating the equivalent dose (D_e) in polymineral fine grains extracted from colluvia from various sites in Germany. First, we report the behaviour of three OSL signals: (i) blue-stimulated, (ii) infrared-stimulated luminescence, and (iii) blue-stimulated luminescence following infrared (IR) stimulation, using a near-UV (290-380 nm) detection window in each case. For these three signals, there is a significant change in sensitivity with regeneration cycle; this change can be compensated for using the response to a fixed test dose after each natural or regenerated measurement. The source of the three luminescence signals is then investigated using pulse-anneal and elevated-temperature experiments. Fading tests on laboratory-induced signals show that although the IR signals fade by up to 23% in 15 ...

2001-02-01

240

Detection of multiple AE signal by triaxial hodogram analysis; Sanjiku hodogram ho ni yoru taju acoustic emission no kenshutsu  

Energy Technology Data Exchange (ETDEWEB)

In order to evaluate dynamic behavior of underground cracks, analysis and detection were attempted on multiple acoustic emission (AE) events. The multiple AE is a phenomenon in which multiple AE signals generated by underground cracks developed in an extremely short time interval are superimposed, and observed as one AE event. The multiple AE signal consists of two AE signals, whereas the second P-wave is supposed to have been inputted before the first S-wave is inputted. The first P-wave is inputted first, where linear three-dimensional particle movements are observed, but the movements are made random due to scattering and sensor characteristics. When the second P-wave is inputted, the linear particle movements are observed again, but are superimposed with the existing input signals and become multiple AE, which creates poor S/N ratio. The multiple AE detection determines it a multiple AE event when ...

1997-05-27

241

Vertical array receptions of the Heard Island transmissions  

Energy Technology Data Exchange (ETDEWEB)

The Heard Island Feasibility Test (HIFT) demonstrated that coded acoustic signals could be detected at ranges up to 18,000 km with currently available source technology. This paper describes one component of the HIFT where a large aperture vertical line array was deployed to record the signals transmitted from Heard Island. We have performed four analysis Of the VLA receptions, of the Heard Island signals. All four suggest the presence of higher order modes. The frequency- vertical wavenumber analysis and the modal beamforming indicate that mode 3 has the highest amplitude while the modal fitting suggests that made 5--6 are largest. It is difficult to resolve the differences since the SNR at the VLA, nearly 18,000 km with a transmission loss of around 145 dB, is quite low. Individual arrivals could not be distinguished because of the long integration time necessitated by the low SNR.

1993-03-23

242

Role of MRI in the diagnostic evaluation of parotid diseases  

International Nuclear Information System (INIS)

MRI findings in 13 patients with monolateral parotid tumor were compared with US, sialographic and CT findings. MRI did not allow an accurate diagnosis in 2 patients with diffuse chronic parotitis. MRI was superior to CT in 1 case in defining the intraglandular site of the lesion, and in 2 patients in showing the extraglandular involvement. MRI proved to be superior to CT thanks to its contrast resolution and to multiplanar imaging. MRI high contrast resolution made it possible to demonstrate neoplastic lesions of 4 mm in diameter. The lesion has low signal intensity on T1-weighted images and high signal intensity on T2-weighted. Parotid tumors cannot be characterized by signal intensity alone: only morphology allows to discriminate between benign and malignant lesions. To conclude, US is a screening method, while MRI is helpful in detecting multifocal lesions and in evaluating the tumor extent.

1988-01-01

243

Particle Swarm Optimization and gravitational wave data analysis: Performance on a binary inspiral testbed  

CERN Document Server

The detection and estimation of gravitational wave (GW) signals belonging to a parameterized family of waveforms requires, in general, the numerical maximization of a data-dependent function of the signal parameters. Due to noise in the data, the function to be maximized is often highly multi-modal with numerous local maxima. Searching for the global maximum then becomes computationally expensive, which in turn can limit the scientific scope of the search. Stochastic optimization is one possible approach to reducing computational costs in such applications. We report results from a first investigation of the Particle Swarm Optimization (PSO) method in this context. The method is applied to a testbed motivated by the problem of detection and estimation of a binary inspiral signal. Our results show that PSO works well in the presence of high multi-modality, making it a viable candidate method for further applications in GW ...

2010-01-01

244

Paroxysmal nocturnal hemoglobinuria: a case report of MR, CT findings  

Energy Technology Data Exchange (ETDEWEB)

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, acquired disease involving multiple hematopoietic cell lines. Characteristics of PNH are intrinsic hemolytic anemia, iron deficiency anemia and venous thrombosis. We report a case of PNH with characterostoc MR and CT findings. The signal intensity of renal cortex was lower than that of medulla on both T1-and T2-weighted MR imaging. On T2 weighted MR images, the liver showed very low signal intensity but the signal intensity of the spleen was normal. On precontrast CT the attenuation of renal cortex was higher than that of renal medulla and the attenuation of liver was higher than that of the spleen. These findings of MR imaging and CT were the result from the deposition of hemosiderin in the cells of proximal convoluted tubules and transfusional hemosiderosis of liver.

1995-10-15

245

Onset of nucleate boiling and onset of fully developed subcooled boiling using pressure transducers signals spectral analysis  

International Nuclear Information System (INIS)

The experimental technique used for detection of subcooled boiling through analysis of the fluctuation contained in pressure transducer signals is presented. This work was partly conducted at the Institut fuer Kerntechnik und zertoerungsfreie Pruefverfahren von Hannover (IKPH, Germany) in a thermal-hydraulic circuit with one electrically heated rod with annular geometry test section. Piezo resistive pressure sensors are used for onset of nucleate boiling (ONB) and onset of fully developed boiling (OFDB) detection using spectral analysis/ signal correlation techniques. Experimental results are interpreted by phenomenological analysis of these two points and compared with existing correlation. The results allow to conclude that this technique is adequate for the detection and monitoring of the ONB and OFDB. (author)

246

Onset of nucleate boiling and onset of fully developed subcooled boiling using pressure transducers signals spectral analysis  

Energy Technology Data Exchange (ETDEWEB)

The experimental technique used for detection of subcooled boiling through analysis of the fluctuation contained in pressure transducer signals is presented. This work was partly conducted at the Institut fuer Kerntechnik und zertoerungsfreie Pruefverfahren von Hannover (IKPH, Germany) in a thermal-hydraulic circuit with one electrically heated rod with annular geometry test section. Piezo resistive pressure sensors are used for onset of nucleate boiling (ONB) and onset of fully developed boiling (OFDB) detection using spectral analysis/ signal correlation techniques. Experimental results are interpreted by phenomenological analysis of these two points and compared with existing correlation. The results allow to conclude that this technique is adequate for the detection and monitoring of the ONB and OFDB. (author)

2001-12-01

247

Multiscale morphology analysis and its application to fault diagnosis  

Science.gov (United States)

A novel approach to fault diagnosis is proposed using multiscale morphology analysis to extract impulsive features from the signals with strong background noise. Multiscale morphology is applied to one-dimensional signal by defining both the length and height scales of structuring elements (SEs). A local-peak-value based adaptive algorithm is also introduced. The new approach makes the selection of SEs more transparent and is independent of empirical rules. Both simulated impulsive and vibration signals of two defective roller bearings are employed to validate the proposed algorithm. The roller bearing faults presented in the validation include both inner and outer race faults. The test results show that the multiscale morphology analysis is effective and robust to extract morphological features.

2008-04-01

248

Multifractal Fourier detrended cross-correlation analysis of traffic signals  

Science.gov (United States)

Multifractal detrended cross-correlation analysis (MF-DXA) has been developed to detect the long-range power-law cross-correlation of considered signals in the presence of non-stationarity. However, crossovers arising from extrinsic periodic trends make the scaling behavior difficult to analyze. We introduce a Fourier filtering method to eliminate the trend effects and systematically investigate the multifractal cross-correlation of simulated and real traffic signals. The crossover locations are found approximately corresponding to the periods of underlying trend. Traffic velocity on one road and flows on adjacent roads show strong cross-correlation. They also present weak multifractality after periodic trends are removed. The traffic velocity and flow are cross-correlated in opposite directions which is accordant to their actual evolution.

2011-10-01

249

Method and device for identifying different species of honeybees  

Energy Technology Data Exchange (ETDEWEB)

A method and device have been provided for distinguishing Africanized honeybees from European honeybees. The method is based on the discovery of a distinct difference in the acoustical signatures of these two species of honeybees in flight. The European honeybee signature has a fundamental power peak in the 210 to 240 Hz range while the Africanized honeybee signature has a fundamental power peak in the 260 to 290 Hz range. The acoustic signal produced by honeybees is analyzed by means of a detecting device to quickly determine the honeybee species through the detection of the presence of frequencies in one of these distinct ranges. The device includes a microphone for acoustical signal detection which feeds the detected signal into a frequency analyzer which is designed to detect the presence of either of the known fundamental wingbeat frequencies unique to the acoustical signatures of these species as an indication of the ...

1989-01-01

250

Ion beam induced charge imaging of epitaxial GaN detectors  

Energy Technology Data Exchange (ETDEWEB)

We report the use of ion beam induced charge imaging to characterise the charge signal uniformity of epitaxial gallium nitride radiation detectors. The detectors were fabricated from 2 {mu}m thick semi-insulating gallium nitride, grown by MOCVD on a sapphire substrate. A carrier concentration of 1.4x10{sup 15} cm{sup -3} was measured using capacitance-voltage measurements. Ion beam induced charge imaging was carried out with a 2 MeV alpha particle beam focussed to a 3 {mu}m diameter and raster scanned across the device. The resulting ion beam images show excellent charge signal uniformity in this material with no evidence of material defects or polycrystalline structure on the micrometer length scale. No evidence of charge signal trapping was observed in these devices.

2004-09-21

251

Interpolating atmospheric water vapor delay by incorporating terrain elevation information  

British Library Electronic Table of Contents (United Kingdom)

In radio signal-based observing systems, such as Global Positioning System (GPS) and Interferometric Synthetic Aperture Radar (InSAR), the water vapor in the atmosphere will cause delays during the signal transmission. Such delays vary significantly with terrain elevation. In the case when atmospheric delays are to be eliminated from the measured raw signals, spatial interpolators may be needed. By taking advantage of available terrain elevation information during spatial interpolation process, the accuracy of the atmospheric delay mapping can be considerably improved. This paper first reviews three elevation-dependent water vapor interpolation models, i.e., the Best Linear Unbiased Estimator in combination with the water vapor Height Scaling Model (BLUE?+?HSM), the Best Linear Unbiased Es...

2011-01-01

252

Hypoxia decreases sclerostin expression and increases Wnt signaling in osteoblasts  

British Library Electronic Table of Contents (United Kingdom)

Mutations in sclerostin function or expression cause sclerosing bone dysplasias, involving decreased antagonism of Wnt/Lrp5 signaling. Conversely, deletion of the VHL tumor suppressor in osteoblasts, which stabilize HIF-a isoforms and thereby enables HIF-a/b-driven gene transcription, increases bone mineral content and cross-sectional area compared to wild-type controls. We examined the influence of cellular hypoxia (1% oxygen) upon sclerostin expression and canonical Wnt signaling. Osteoblasts and osteocytes cultured under hypoxia revealed decreased sclerostin transcript and protein, and increased expression and nuclear localization of activated b-catenin. Similarly, both hypoxia and the hypoxia mimetic DFO increased b-catenin gene reporter activity. Hypoxia and its mimetics increased exp...

2010-01-01

253

High-vacuum time-resolved laser-induced incandescence of?flame-generated soot  

British Library Electronic Table of Contents (United Kingdom)

We have measured time-resolved laser-induced incandescence of flame-generated soot under high-vacuum conditions (4.1?10?6 mbar) at an excitation wavelength of 532 nm with laser fluences spanning 0.06?0.5 J/cm2. We generated soot in an ethylene/air diffusion flame, introduced it into the vacuum system with an aerodynamic lens, heated it using a pulsed laser with a spatially homogeneous and temporally smooth laser profile, and recorded LII temporal profiles at 685 nm. At low laser fluences LII signal decay rates are slow, and LII signals persist beyond the residence time of the soot particles in the detection region. At these fluences, the temporal maximum of the LII signal increases nearly linearly with increasing laser fluence until reaching a plateau at ?0.18?J/cm2. At higher fluences, th...

2011-01-01

254

Feedwater control device for a reactor  

International Nuclear Information System (INIS)

Purpose: To eliminate the water level deviation due to the recycling flowrate, as well as enable a stable control to a reference value even upon changes in the recycling flowrate caused by the variation in the opening degree of a minimum flow valve. Constitution: Reactor recycling system comprises a feedwater pump, a flowrate control valve, a reactor water level detector, and a minimum flow line and a minimum flow valve for preventing the overheating of the feedwater pump at a low flowrate. A flowrate compensator is further disposed, in which a recycling flowrate signal is subtracted from a pump flow rate signal and the result is fedback as a compensated pump flowrate signal. This enables the control system to operate at a rapid response for suppressing the effect of the recycling flowrate as external disturbance, whereby the water level in the reactor can be controlled stably to the reference level and the possibility ...

1981-11-18

255

Eddy currents signal processing for steam generator inspection in PWR nuclear power plants  

International Nuclear Information System (INIS)

Steam generator tubes in nuclear power plants are periodically checked by means of eddy current probes. The output of a probe is composed of three types of signals: known events (rolling zone, support plates, U-bend part), noise (mainly metallurgical noise) and possible flaws. The latter are random transients, both in arrival time and in shape: they have to be detected and then estimated, before to be fed to the high level stages of a diagnostic system. The objective of the study presented is to develop a semi-automatic system, which could manage and process more than 1 M-bytes of data per tube and provide an operator with reliable diagnostics proposals within a few minutes. This can be achieved only by cooperation of several digital signal processing techniques: detection, segmentation, estimation, noise subtraction, adaptive filtering, modelization, pattern recognition. The paper describes some of these items.

1992-01-01

256

Dynamic control rod worth measurement of Yonggwang Unit 1 cycle 14  

Energy Technology Data Exchange (ETDEWEB)

A dynamic control rod worth measurement was performed for control bank D, C, B, and A of Yonggwang unit 1 cycle 14 during its low power physics test. MASTER was used for three-dimensional core kinetics calculations required to convert excore detector signal into static rod worth, using the same modeling and cross sections as ANC which was used for the core static design. A signal curve fitting method was proposed to solve a low signal problem due to large amount of rod worth, which leads to the distortion of resulting static worth. The static worths measured in this test well agreed with the predicted worth of design within {+-}15% which is a test requirement of rod worth measurement.

2002-05-01

257

Dynamic control rod worth measurement of Yonggwang Unit 1 cycle 14  

International Nuclear Information System (INIS)

A dynamic control rod worth measurement was performed for control bank D, C, B, and A of Yonggwang unit 1 cycle 14 during its low power physics test. MASTER was used for three-dimensional core kinetics calculations required to convert excore detector signal into static rod worth, using the same modeling and cross sections as ANC which was used for the core static design. A signal curve fitting method was proposed to solve a low signal problem due to large amount of rod worth, which leads to the distortion of resulting static worth. The static worths measured in this test well agreed with the predicted worth of design within #+-#15% which is a test requirement of rod worth measurement.

2002-05-01

258

Discriminating between a Stochastic Gravitational Wave Background and Instrument Noise  

CERN Document Server

The detection of a stochastic background of gravitational waves could significantly impact our understanding of the physical processes that shaped the early Universe. The challenge lies in separating the cosmological signal from other stochastic processes such as instrument noise and astrophysical foregrounds. One approach is to build two or more detectors and cross correlate their output, thereby enhancing the common gravitational wave signal relative to the uncorrelated instrument noise. When only one detector is available, as will likely be the case with the Laser Interferometer Space Antenna (LISA), alternative analysis techniques must be developed. Here we show that models of the noise and signal transfer functions can be used to tease apart the gravitational and instrument noise contributions. We discuss the role of gravitational wave insensitive "null channels" formed from particular combinations of the time delay ...

2010-01-01

259

Acute femoral neck fracture  

International Nuclear Information System (INIS)

Ten patients with traumatic femoral neck fracture were studied with MR imaging (0.5 T, Magnetom, Siemens): unenhanced (multiecho, TR/TE = 1,600/30--240 [repetition time/echo time, msec]; gradient echo, TR/TE = 315/14, #theta# = 90 degrees) and Gd-DTPA enhanced (0.1 mM/kg body weight, Magnevist, Schering; gradient echo, TR/TE = 315/14, #theta# = 90 degrees). MR images were compared with clinical-radiographic findings. Digital subtraction angiography of the femoral head (FH) in five patients showed complete interruption of blood supply to the FH in three patients (signal intensity of FH did not increase on postcontrast images) and intact FH arteries in two patients (FH signal increased on postcontrast images, as did the healthy-side signal).

260

A novel wavelet transform aided neural network based transmission line fault analysis method  

Energy Technology Data Exchange (ETDEWEB)

In the present scenario of market driven business, power supply has become more like a commodity. Reliable and quality power need to be ensured to meet customer requirements. In such a situation, it is extremely important that transmission line faults be identified accurately, reliably and in quick time. Advanced signal processing tools such as discrete wavelet transform (DWT) can be used very effectively for parameterisation and characterization of the fault signals. On the other hand, properly configured neural network (NN) can be utilized for classification of the faults based on the DWT signal. The present contribution uses electromagnetic transient program (EMTP) for modeling of a real transmission system and MATLAB for DWT and NN. Various types of faults have been simulated at different locations along the transmission line and an attempt has been made to correctly identify and locate the fault. (author)

2009-06-15

261

A novel wavelet transform aided neural network based transmission line fault analysis method  

British Library Electronic Table of Contents (United Kingdom)

In the present scenario of market driven business, power supply has become more like a commodity. Reliable and quality power need to be ensured to meet customer requirements. In such a situation, it is extremely important that transmission line faults be identified accurately, reliably and in quick time. Advanced signal processing tools such as discrete wavelet transform (DWT) can be used very effectively for parameterisation and characterization of the fault signals. On the other hand, properly configured neural network (NN) can be utilized for classification of the faults based on the DWT signal. The present contribution uses electromagnetic transient program (EMTP) for modeling of a real transmission system and MATLAB for DWT and NN. Various types of faults have been simulated at differ...

2009-01-01

262

A large solid angle, high stopping power Bragg curve spectrometer for coincidence measurements  

Energy Technology Data Exchange (ETDEWEB)

A large acceptance, high stopping power, Bragg curve spectrometer has been developed for use in coincidence experiments with heavy ions. The electron collection fields are radial and position information is obtained from a resistive anode. The detector is 60 cm deep and operates at pressures of up to 2.5 atm of P-10 gas. It is mated to a scattering chamber which allows it to be moved out of plane during coincidence measurements. The detector design was aided by the results of computer simulations of the electron collection process in the detector, and of the signal processing in the electronics. The signals from the Bragg curve spectrometer are recorded in a waveform digitizer and the Bragg peak height, range, position and pileup rejection information are determined from software analysis of the recorded signals. Factors limiting the performance of the detector are discussed, and results obtained with the detector are ...

1991-09-01

263

A large solid angle, high stopping power Bragg curve spectrometer for coincidence measurements  

International Nuclear Information System (INIS)

A large acceptance, high stopping power, Bragg curve spectrometer has been developed for use in coincidence experiments with heavy ions. The electron collection fields are radial and position information is obtained from a resistive anode. The detector is 60 cm deep and operates at pressures of up to 2.5 atm of P-10 gas. It is mated to a scattering chamber which allows it to be moved out of plane during coincidence measurements. The detector design was aided by the results of computer simulations of the electron collection process in the detector, and of the signal processing in the electronics. The signals from the Bragg curve spectrometer are recorded in a waveform digitizer and the Bragg peak height, range, position and pileup rejection information are determined from software analysis of the recorded signals. Factors limiting the performance of the detector are discussed, and results obtained with the detector are ...

264

skittles, a Drosophila phosphatidylinositol 4-phosphate 5-kinase, is required for cell viability, germline development and bristle morphology, but not for neurotransmitter release.  

UK PubMed Central (United Kingdom)

The phosphatidylinositol pathway is implicated in the regulation of numerous cellular functions and responses to extracellular signals. An important branching point in the pathway is the phosphorylation...Full Text Available

1998-12-01

265

p53 Regulates Oxidative Stress-Mediated Retrograde Signaling: A Novel Mechanism for Chemotherapy-Induced Cardiac Injury  

UK PubMed Central (United Kingdom)

The side effects of cancer therapy on normal tissues limit the success of therapy. Generation of reactive oxygen species (ROS) has been implicated for numerous chemotherapeutic agents including doxorubicin...Full Text Available

266

ch6-1 - NASA's History Office  

Science.gov (United States)

Composed of Sun sensors, the Canopus sensor, the inertial reference unit, ... The heart of the system was a 100-pound-thrust rocket whose hypergolic, ... The spacecraft's low-gain antenna picked up all incoming signals from the NASA-JPL ...

267

Visually mediated species and neighbour recognition in fiddler crabs (Uca mjoebergi and Uca capricornis)  

UK PubMed Central (United Kingdom)

Mating signals are often directed at numerous senses and provide information about species identity, gender, receptiveness, individual identity and mate quality. Given the diversity of colourful body...Full Text Available

2006-07-07

268

Use of lanthanide shift reagents with [sup 31]P FT-NMR spectroscopy to analyze concentrated lake-water samples  

Energy Technology Data Exchange (ETDEWEB)

Several lanthanide shift reagents (LSR) were synthesized from praseodymium, europium, dysprosium, and terbium using ethylenediaminetetraacetic acid, trans-1,2-diaminocyclohexane-N,N,N[prime],N[prime]-tetraacetic acid, and diethylenetriaminepentaacetic acid for the purpose of separating overlapping [sup 31]P FT-NMR spectral signals of dissolved organic phosphorus compounds present in concentrated lake-water samples. The extent of change in signal position and line width of several known phosphorus compounds dissolved in pure water was examined as a function of solution pH and the molar ratio of LSR to phosphorus. Praseodymium ethylenediaminetetraacetate (PrEDTA) was determined to be the most effective LSR. Concentrated lake-water samples mixed with PrEDTA were examined with [sup 31]P FT-NMR. The use of PrEDTA provided separation of overlapping signals, indicated that phosphorus compounds were becoming isolated from the ...

1994-08-01

269

Use of Forward Genetics to Discover Novel Regulators of NF-?B  

UK PubMed Central (United Kingdom)

Forward and reverse genetic experiments have both played important roles in revealing critical aspects of mammalian signal transduction pathways in cell culture experiments. Only recently have we begun...Full Text Available

2010-06-01

270

Unbiased Transcriptional Comparisons of Generalist and Specialist Herbivores Feeding on Progressively Defenseless Nicotiana attenuata Plants  

UK PubMed Central (United Kingdom)

BackgroundHerbivore feeding elicits dramatic increases in defenses, most of which require jasmonate (JA) signaling, and against which specialist herbivores are thought to be better...Full Text Available

271

UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications  

UK PubMed Central (United Kingdom)

Cytosine methylation in DNA is a major epigenetic signal, and plays a central role in propagating chromatin status during cell division. However the mechanistic links between DNA methylation...Full Text Available

2009-01-01

272

Two- level fuzzy control of large-scale systems and Its application into Pss design  

International Nuclear Information System (INIS)

This paper propose a two-level suboptimal control using fuzzy predication to control large-scale systems. A class of large-scale linear systems composed of interconnected subsystems is investigated. The overall control problem that is posed as a minimization of overall objective function, which is considered to be of quadratic form, is reduced to some optimization problems of lower order (sub)systems. The control input of each subsystem is composed of two signals. The first represents the local control signal (first level) and the second is the predication signal (second level). In fact, the second signals is the prediction of other subsystems. It applies to each subsystem at every specified sample time (coordination sample times ). The fuzzy logic theory is used for interaction prediction, where the prediction single is constructed by a set of fuzzy sets with respect to state variable in an appropriate ...

2003-01-01

273

Two Proline-Rich Nuclear Localization Signals in the Amino- and Carboxyl-Terminal Regions of the Borna Disease Virus Phosphoprotein  

UK PubMed Central (United Kingdom)

Borna disease virus (BDV) uses a unique strategy of replication and transcription which takes place in the nucleus, unlike other known, nonsegmented, negative-stranded RNA viruses of animal origin....Full Text Available

1998-12-01

274

Trypanosoma cruzi glycosomal glyceraldehyde-3-phosphate dehydrogenase does not conform to the 'hotspot' topogenic signal model.  

UK PubMed Central (United Kingdom)

The genes which encode glycosomal glyceraldehyde-phosphate dehydrogenase (gGAPDH) of Trypanosoma cruzi are arranged as a tandemly repeated pair on a single chromosome and are identical at the level...Full Text Available

1990-09-01

275

Transforming growth factor-beta signaling in thoracic aortic aneurysm development: a paradox in pathogenesis  

UK PubMed Central (United Kingdom)

Thoracic aortic aneurysms (TAAs) are potentially devastating, and due to their asymptomatic behavior, pose a serious health risk characterized by the lack of medical treatment options and high...Full Text Available

2009-01-01

276

Tissue Effect on Genetic Control of Transcript Isoform Variation  

UK PubMed Central (United Kingdom)

Current genome-wide association studies (GWAS) are moving towards the use of large cohorts of primary cell lines to study a disease of interest and to assign biological relevance to the genetic signals...Full Text Available

2009-08-01

277

Three-Dimensional Traction Force Microscopy: A New Tool for Quantifying Cell-Matrix Interactions  

UK PubMed Central (United Kingdom)

The interactions between biochemical processes and mechanical signaling play important roles during various cellular processes such as wound healing, embryogenesis, metastasis, and cell migration. While...Full Text Available

278

The first long-lived mutants: discovery of the insulin/IGF-1 pathway for ageing  

UK PubMed Central (United Kingdom)

Inhibiting insulin/IGF-1 signalling extends lifespan and delays age-related disease in species throughout the animal kingdom. This life-extension pathway, the first to be defined, was discovered through...Full Text Available

2011-01-12

279

The Serotonin Transporter Polymorphism rs25531 Is Associated with Irritable Bowel Syndrome  

UK PubMed Central (United Kingdom)

Irritable bowel syndrome is a frequent gastrointestinal disorder of unknown etiology. The serotonin transporter regulates the intensity and duration of serotonin signaling in the gut and is,...Full Text Available

2009-12-01

280

The Regulation of Aging and Longevity  

UK PubMed Central (United Kingdom)

p53 plays a critical role in tumor suppression. As a transcription factor, in response to stress signals, p53 regulates its target genes and initiates stress responses, including cell cycle arrest,...Full Text Available

2011-04-01

281

The QseC Adrenergic Signaling Cascade in Enterohemorrhagic E. coli (EHEC)  

UK PubMed Central (United Kingdom)

The ability to respond to stress is at the core of an organism's survival. The hormones epinephrine and norepinephrine play a central role in stress responses in mammals, which require the synchronized...Full Text Available

2009-08-01

282

The Pseudoreceptor BMP and Activin Membrane-bound Inhibitor Positively Modulates Wnt/?-Catenin Signaling*  

UK PubMed Central (United Kingdom)

The canonical Wnt/β-catenin pathway plays a pivotal role in regulating embryogenesis and tumorigenesis by promoting cell proliferation. BAMBI (BMP and activin membrane-bound inhibitor) has...Full Text Available

2008-11-28

283

The Induction of APC with a Distinct Tolerogenic Phenotype via Contact-Dependent STAT3 Activation  

UK PubMed Central (United Kingdom)

BackgroundActivation of the signal transducer and activator of transcription 3 (STAT3) within antigen presenting cells (APCs) is linked to abnormal APCs differentiation and function....Full Text Available

284

The Differing Impact of Multisensory and Unisensory Integration on Behavior  

UK PubMed Central (United Kingdom)

Pooling and synthesizing signals across different senses often enhances responses to the event from which they are derived. Here we examine whether multisensory response enhancements are attributable...Full Text Available

2009-04-15

285

Terminated Exploding Wire Energy Source.  

Science.gov (United States)

By placing a discharge or 'dump' tube across an exploding bridgewire load, it is possible to by-pass the electrical energy and terminate the explosion of the wire. The dump tube is triggered by a signal derived from the energy removed from the storage cap...

1965-01-01

286

Targeted Deletion of Somatotroph Insulin-Like Growth Factor-I Signaling in a Cell-Specific Knockout Mouse Model  

UK PubMed Central (United Kingdom)

The role of IGF-I in the negative regulation of GH expression and release is demonstrated by in vitro and in vivo models; however, the targets and mechanisms of IGF-I...Full Text Available

2010-05-01

287

TTF HOM Data Analysis with Curve Fitting Method  

Energy Technology Data Exchange (ETDEWEB)

To investigate the possibility of using HOM signals induced in SC cavities as beam and cavity diagnostics, narrow band (20 MHz) data was recorded around the strong TE111-6(6{pi}/9-like) dipole modes (1.7 GHz) in the 40 L-band (1.3 GHz) cavities at the DESY TTF facility. The analyses of these data have so far focused on using a Singular Value Decomposition (SVD) technique to correlate the signals with each other and data from conventional BPMs to show the dipole signals provide an alternate means of measuring the beam trajectory. However, these analyses do not extract the modal information (i.e., frequencies and Q's of the nearly degenerate horizontal and vertical modes). In this paper, we described a method to fit the signal frequency spectrum to obtain this information, and then use the resulting mode amplitudes and phases together with conventional BPM data to determine the mode polarizations ...

2009-07-14

288

TFIIH Operates through an Expanded Proximal Promoter To Fine-Tune c-myc Expression  

UK PubMed Central (United Kingdom)

A continuous stream of activating and repressing signals is processed by the transcription complex paused at the promoter of the c-myc proto-oncogene. The general transcription factor...Full Text Available

2005-01-01

289

T cell-engaging BiTE antibodies specific for EGFR potently eliminate KRAS- and BRAF-mutated colorectal cancer cells  

UK PubMed Central (United Kingdom)

Epidermal growth factor receptor (EGFR)-specific monoclonal antibodies predominantly inhibit colorectal cancer (CRC) growth by interfering with receptor signaling. Recent analyses have shown that patients...Full Text Available

2010-07-13

290

Synchronous Averaging for Asynchronous Sampling Data  

Science.gov (United States)

The progress of digital audio technology enabled the familiar use of the products such as CD and DAT in the acoustic measurement. For example, a signal reproduced with CD player is inputted into a subject of measurement and DAT recorder records its response. However, the sampling cannot be synchronized completely with the input signal although both nominal sample rates are set up equally, because player and recorder work independently. It is the most popular software solution to perform the synchronous addition after converting the recorded signal into the original sampling rate. However, the rate conversion also has the error due to the windowing in the high frequency region of processed signal. This paper proposes a new method for averaging asynchronous sampling data to solve these problems. To evaluate performance, the transfer function of only measuring equipment estimated from asynchronous sampling ...

2005-01-01

291

Synaptic Signaling and Aberrant RNA Splicing in Autism Spectrum Disorders  

UK PubMed Central (United Kingdom)

Interactions between presynaptic and postsynaptic cellular adhesion molecules (CAMs) drive synapse maturation during development. These trans-synaptic interactions are regulated by alternative splicing...Full Text Available

292

Surface EMG pattern recognition for real-time control of a wrist exoskeleton  

UK PubMed Central (United Kingdom)

BackgroundSurface electromyography (sEMG) signals have been used in numerous studies for the classification of hand gestures and movements and successfully implemented in the position...Full Text Available

293

Support vector machines for nuclear reactor state estimation  

Energy Technology Data Exchange (ETDEWEB)

Validation of nuclear power reactor signals is often performed by comparing signal prototypes with the actual reactor signals. The signal prototypes are often computed based on empirical data. The implementation of an estimation algorithm which can make predictions on limited data is an important issue. A new machine learning algorithm called support vector machines (SVMS) recently developed by Vladimir Vapnik and his coworkers enables a high level of generalization with finite high-dimensional data. The improved generalization in comparison with standard methods like neural networks is due mainly to the following characteristics of the method. The input data space is transformed into a high-dimensional feature space using a kernel function, and the learning problem is formulated as a convex quadratic programming problem with a unique solution. In this paper the authors have applied the SVM method for ...

2000-02-14

294

Substance P Signaling Contributes to Granuloma Formation in Taenia crassiceps Infection, a Murine Model of Cysticercosis  

UK PubMed Central (United Kingdom)

Cysticercosis is an infection with larval cysts of the cestode Taenia solium. Through pathways that are incompletely understood, dying parasites initiate a granulomatous reaction that,...Full Text Available

2010-01-01

295

Structural basis of ligand binding by a c-di-GMP riboswitch  

UK PubMed Central (United Kingdom)

The second messenger signaling molecule bis-(3′-5′)-cyclic dimeric guanosine monophosphate (c-di-GMP) regulates many processes in bacteria, including motility, pathogenesis,...Full Text Available

2009-12-01

296

Stabilization of ?-catenin induces pancreas tumor formation  

UK PubMed Central (United Kingdom)

Background & Aimsβ-catenin signaling within the canonical Wnt pathway is essential for pancreas development. However, the pathway is normally down-regulated...Full Text Available

2008-10-01

297

Six orders of magnitude dynamic range in capillary electrophoresis with ultrasensitive laser-induced fluorescence detection  

UK PubMed Central (United Kingdom)

An ultrasensitive laser-induced fluorescence detector was used with capillary electrophoresis for the study of 5-carboxy-tetramethylrhodamine. The raw signal from the detector provided roughly...Full Text Available

2009-12-15

298

Signal transduction underlying the control of urinary bladder smooth muscle tone by muscarinic receptors and ?-adrenoceptors  

UK PubMed Central (United Kingdom)

The normal physiological contraction of the urinary bladder, which is required for voiding, is predominantly mediated by muscarinic receptors, primarily the M3 subtype, with the M2...Full Text Available

2008-06-01

299

Serotype- and strain- dependent contribution of the sensor kinase CovS of the CovRS two-component system to Streptococcus pyogenes pathogenesis  

UK PubMed Central (United Kingdom)

BackgroundThe Streptococcus pyogenes (group A streptococci, GAS) two-component signal transduction system CovRS has been described to be important for pathogenesis...Full Text Available

300

Separating kindling and LTP: Lessons from studies of PKMzeta in developing and adult rats  

UK PubMed Central (United Kingdom)

The kindling model of temporal lobe epilepsy and the memory model of long-term potentiation (LTP) may have common underlying mechanisms. This is evident by the demonstration that certain signaling...Full Text Available

2009-04-10

301

Separate Mechanisms for Audio-Tactile Pitch and Loudness Interactions  

UK PubMed Central (United Kingdom)

A major goal in perceptual neuroscience is to understand how signals from different sensory modalities are combined to produce stable and coherent representations. We previously investigated interactions...Full Text Available

302

Sensitivity of psychophysical measures to signal processor modifications in cochlear implant users  

UK PubMed Central (United Kingdom)

Experienced users of the Clarion cochlear implant were tested acutely with the HiResolution (HiRes) and HiRes Fidelity120 (F120) processing strategies. Three psychophysically-based tests were...Full Text Available

2010-04-01

303

Sensitivity limits for voltage control of P2Y receptor-evoked Ca2+ mobilization in the rat megakaryocyte  

UK PubMed Central (United Kingdom)

G-protein-coupled receptor signalling has been suggested to be voltage dependent in a number of cell types; however, the limits of sensitivity of this potentially important phenomenon are unknown. Using...Full Text Available

2004-02-15

304

STIMPY mediates cytokinin signaling during shoot meristem establishment in Arabidopsis seedlings  

UK PubMed Central (United Kingdom)

The establishment of the primary meristems through proliferation after germination is essential for plant post-embryonic development. Cytokinins have long been considered a key regulator of...Full Text Available

2010-02-15

305

Rhabdomere biogenesis in Drosophila photoreceptors is acutely sensitive to phosphatidic acid levels  

UK PubMed Central (United Kingdom)

Phosphatidic acid (PA) is postulated to have both structural and signaling functions during membrane dynamics in animal cells. In this study, we show that before a critical time period during rhabdomere...Full Text Available

2009-04-06

306

Reversal of Depressed Behaviors by p11 Gene Therapy in the Nucleus Accumbens  

UK PubMed Central (United Kingdom)

The etiology of major depression remains unknown, but dysfunction of serotonergic signaling has long been implicated in the pathophysiology of this disorder. p11 is an S100 family member recently...Full Text Available

2010-10-20

307

Rejuvenating somatotropic signaling: a therapeutical opportunity for premature aging?  

UK PubMed Central (United Kingdom)

We have recently reported that progeroid Zmpste24−/− mice, which exhibit multiple defects that phenocopy Hutchinson-Gilford progeria syndrome, show a profound dysregulation...Full Text Available

308

Regulation of apoptosis by the circadian clock through NF-?B signaling  

UK PubMed Central (United Kingdom)

In mice and humans the circadian rhythm of many biochemical reactions, physiology, and behavior is generated by a transcriptional-translation feedback loop (TTFL) made up of the so-called core clock...Full Text Available

2011-07-19

309

Reducing the effect of penstock pressure pulsations on hydro electric plant power system stabilizer signals  

Energy Technology Data Exchange (ETDEWEB)

A characteristic trait of Francis turbines operating at low-head is pressure pulsations that occur during certain load levels of the generator. These stem from pressure variations across the turbine due to pulsating flow in the draft-tube. This surging action of the water column is related to draft-tube geometry and flow-rate of water in the penstock. The pressure pulsations cause torque variations on the turbine and corresponding electric power pulsations. If electric power is used as a feedback signal to the Power System Stabilizer (PSS), then Mvar and terminal voltage pulsations will occur when the generator is operating in the ``rough zone``. This paper describes field test results for investigating feedforward control from the penstock, draft tube and spiral case pressure to reduce the effects of Mw pulsations on PSS output signals. This investigation involved a PSS with generator power as the feedback signal and the ...

1993-12-01

310

Recognizing brain activities by functional near-infrared spectroscope signal analysis  

UK PubMed Central (United Kingdom)

BackgroundFunctional Near-Infrared Spectroscope (fNIRs) is one of the latest technologies which utilize light in the near-infrared range to determine brain activities. Near-infrared...Full Text Available

311

Rapid Onset of Maternal Vocal Recognition in a Colonially Breeding Mammal, the Australian Sea Lion  

UK PubMed Central (United Kingdom)

BackgroundIn many gregarious mammals, mothers and offspring have developed the abilities to recognise each other using acoustic signals. Such capacity may develop at different rates...Full Text Available

312

RIN4-like proteins mediate resistance protein-derived soybean defense against Pseudomonas syringae  

UK PubMed Central (United Kingdom)

Resistance (R) protein mediated recognition of pathogen avirulence effectors triggers signaling that induces a very robust form of species-specific immunity in plants. The soybean Rpg1-b protein mediates...Full Text Available

2010-11-01

313

Quantitative Analysis of Endocytosis and Turnover of Epidermal Growth Factor (EGF) and EGF Receptor  

UK PubMed Central (United Kingdom)

Binding of epidermal growth factor (EGF) to the EGF receptor (EGFR) initiates signal transduction, ultimately leading to altered gene expression. Ligand-activated EGFR is also rapidly internalized...Full Text Available

2010-03-01

314

Prolonged signaling at the parathyroid hormone receptor by peptide ligands targeted to a specific receptor conformation  

UK PubMed Central (United Kingdom)

The parathyroid hormone receptor (PTHR) is a class B G protein-coupled receptor that plays critical roles in bone and mineral ion metabolism. Ligand binding to the PTHR involves interactions to both...Full Text Available

2008-10-28

315

Prolactin Receptor Signaling Is Essential for Perinatal Brown Adipocyte Function: A Role for Insulin-like Growth Factor-2  

UK PubMed Central (United Kingdom)

BackgroundThe lactogenic hormones prolactin (PRL) and placental lactogens (PL) play central roles in reproduction and mammary development. Their actions are mediated via binding...Full Text Available

316

Polymorphisms associated with type 2 diabetes in familial longevity: The Leiden Longevity Study  

UK PubMed Central (United Kingdom)

Human longevity is in part genetically determined, and the insulin/IGF-1 signal transduction (IIS) pathway has consistently been implicated. In humans, type 2 diabetes is a frequent disease that results...Full Text Available

317

Physical Basis for the Lg/P Discriminant: General Properties and Preliminary Modeling.  

Science.gov (United States)

A critical problem for reliable implementation of regional discrimination is incomplete understanding of how regional seismic signals depend on physical characteristics of the source and propagation path to the recording station. This research is directed...

1997-01-01

318

PGE2-regulated wnt signaling and N-acetylcysteine are synergistically hepatoprotective in zebrafish acetaminophen injury  

UK PubMed Central (United Kingdom)

Acetaminophen (APAP) toxicity is the most common drug-induced cause of acute liver failure in the United States. The only available treatment, N-acetylcysteine (NAC), has a limited...Full Text Available

2010-10-05

319

PDP-1 Links the TGF-? and IIS Pathways to Regulate Longevity, Development, and Metabolism  

UK PubMed Central (United Kingdom)

The insulin/IGF-1 signaling (IIS) pathway is a conserved regulator of longevity, development, and metabolism. In Caenorhabditis elegans IIS involves activation of DAF-2 (insulin/IGF-1...Full Text Available

2011-04-01

320

PAS Domain Residues Involved in Signal Transduction by the Aer Redox Sensor of Escherichia coli  

UK PubMed Central (United Kingdom)

SummaryPAS domains sense oxygen, redox potential and light, and are implicated in behavior, circadian rhythmicity, development and metabolic regulation. Although PAS domains are...Full Text Available

2000-05-01

321

Opposing function of mitochondrial prohibitin in aging  

UK PubMed Central (United Kingdom)

While specific signalling cascades involved in aging, such as the insulin/IGF-1 pathway, are well-described, the actual metabolic changes they elicit to prolong lifespan remain obscure. Nevertheless,...Full Text Available

322

On-line plasticity in spoken sentence comprehension: Adapting to time-compressed speech  

UK PubMed Central (United Kingdom)

AbstractListeners show remarkable flexibility in processing variation in speech signal. One striking example is the ease with which they adapt to novel speech distortions such as listening...Full Text Available

2010-01-01

323

New insights into purinergic receptor signaling in neuronal differentiation, neuroprotection, and brain disorders  

UK PubMed Central (United Kingdom)

Ionotropic P2X and metabotropic P2Y purinergic receptors are expressed in the central nervous system and participate in the synaptic process particularly associated with acetylcholine, GABA, and glutamate...Full Text Available

2007-09-01

324

Neutral endopeptidase inhibits prostate cancer cell migration by blocking focal adhesion kinase signaling  

UK PubMed Central (United Kingdom)

Neutral endopeptidase 24.11 (NEP, CD10) is a cell-surface enzyme expressed by prostatic epithelial cells that cleaves and inactivates neuropeptides implicated in the growth of androgen-independent prostate...Full Text Available

2000-12-01

325

Neural-network-based voice-tracking algorithm  

Science.gov (United States)

A voice-tracking algorithm was developed and tested for the purposes of electronically separating the voice signals of simultaneous talkers. Many individuals suffer from hearing disorders that often inhibit their ability to focus on a single speaker in a multiple speaker environment (the cocktail party effect). Digital hearing aid technology makes it possible to implement complex algorithms for speech processing in both the time and frequency domains. In this work, an average magnitude difference function (AMDF) was performed on mixed voice signals in order to determine the fundamental frequencies present in the signals. A time prediction neural network was trained to recognize normal human voice inflection patterns, including rising, falling, rising-falling, and falling-rising patterns. The neural network was designed to track the fundamental frequency of a single talker based on the training procedure. The output of the ...

2002-11-01

326

Near Infrared Dyes as Lifetime Solvatochromic Probes for Micropolarity Measurements of Biological Systems  

UK PubMed Central (United Kingdom)

The polarity of biological mediums controls a host of physiological processes such as digestion, signaling, transportation, metabolism, and excretion. With the recent widespread use of near-infrared...Full Text Available

2007-10-15

327

NKX2-3 Transcriptional Regulation of Endothelin-1 and VEGF Signaling in Human Intestinal Microvascular Endothelial Cells  

UK PubMed Central (United Kingdom)

BackgroundNKX2-3 is associated with inflammatory bowel disease (IBD). NKX2-3 is expressed in microvascular endothelial cells and the muscularis...Full Text Available

328

N A S A T'ECHNICAL, - NASA Technical Reports Server  

Science.gov (United States)

Four temperature sensors were provided instead of the previous two sensors. 4. ... Incoming signals from either one or two ground stations at a frequency of .... The propulsion subsystem consists of a single solid-propellant rocket motor. ...

329

Myelin associated glycoprotein cross-linking triggers its partitioning into lipid rafts, specific signaling events and cytoskeletal rearrangements in oligodendrocytes  

UK PubMed Central (United Kingdom)

Myelin-associated glycoprotein (MAG) has been implicated in inhibition of nerve regeneration in the CNS. This results from interactions between MAG and the Nogo receptor and gangliosides on...Full Text Available

2004-02-01

330

Monitoring system assists in dual-fuel engine knock prevention  

Energy Technology Data Exchange (ETDEWEB)

ABB Industrietechnik AG recently has introduced an augmented version of its Cyldeyt cylinder pressure monitoring system aimed at spark-ignited and diesel/gas, dual-fuel engines. In addition to recording and evaluating cylinder pressure as a means of assessing engine condition, the new Cyldet version now evaluates the cylinder pressure signals to provide protection against pre-ignition related damage. When pre-ignition reaches critical levels, the Cyldet computer relays alarm signals in two stages to the overriding engine control system of the power plant. On receiving the first-stage alarm signal, the engine control system is programmed to adjust one or more engine settings to eliminate preignition - a typical adjustment is to lower charge-air temperature, for example. If such measures fail to eliminate pre-ignition, in the case of a dual-fuel engine, a second alarm signal triggers a reduction in engine ...

1995-03-01

331

Molecular conservation of estrogen-response associated with cell cycle regulation, hormonal carcinogenesis and cancer in zebrafish and human cancer cell lines  

UK PubMed Central (United Kingdom)

BackgroundThe zebrafish is recognized as a versatile cancer and drug screening model. However, it is not known whether the estrogen-responsive genes and signaling pathways that are...Full Text Available

332

Modulation of Expression of the ToxR Regulon in Vibrio cholerae by a Member of the Two-Component Family of Response Regulators  

UK PubMed Central (United Kingdom)

The ToxRS system in Vibrio cholerae plays a central role in the modulation of virulence gene expression in response to environmental stimuli. An integration of multiple signalling inputs...Full Text Available

1998-12-01

333

Modulation of B-cell endoplasmic reticulum calcium homeostasis by Epstein-Barr virus Latent Membrane Protein-1  

UK PubMed Central (United Kingdom)

BackgroundCalcium signaling plays an important role in B lymphocyte survival and activation, and is critically dependent on the inositol-1,4,5-tris-phosphate-induced...Full Text Available

334

Microprocessor system controlling gas-carburizing process  

Energy Technology Data Exchange (ETDEWEB)

This report introduces a microprocessor system composed of a Z-80 single-board computer controlling a gas-carburizing process. The system has 7 analogical input and output signals 24 switch signal-input and 12 switch signal-output signals, which are applicable for temperature, carbon potential, and mechanical-movement control of multipurpose sealed furnaces, or for mutiple-zone temperature, carbon potential, and mechanical-movement control of continuous gas carburizing furnaces; or for distributed control of pit-type carburizing furnaces. The setpoints of variables, such as treating time, temperature, carbon potential of carburizing period, carbon potential of diffusion period, depth of carburizing layer, P.I.D. etc., are entered by keyboard and stored into memories, and actual values are displayed by digital tubes. Furthermore, the fault of thermocouple, oxygen probe, or infrared CO/sub 2/ analyzer; ...

1986-01-01

335

Method for controlling the liquid level of a steam generator for a sodium-cooled fast breeder reactor  

International Nuclear Information System (INIS)

Object: To control the average liquid level of each steam generator at a constant level irrespective of the flow rate of sodium thereby to decrease change in the retained amount of sodium and at the same time to improve the load response characteristic. Construction: A method for decreasing to as large an extent as possible a change in the amount of sodium retained in a steam generator due to change in the flow rate, which comprises the steps of detecting the main recirculating flow rate of liquid sodium by the use of a sodium flow rate detector, amplifying the detected flow rate signal depending upon the ratio between the flow rates respectively in a super-heater and a re-heater (distribution ratio), delivering the amplified signal to a function generator which generates a liquid level setting signal for maintaining the respective average liquid levels of the super-heater and the re-heater at constant levels irrespective ...

336

Metabolic labeling and direct imaging of choline phospholipids in vivo  

UK PubMed Central (United Kingdom)

Choline (Cho)-containing phospholipids are the most abundant phospholipids in cellular membranes and play fundamental structural as well as regulatory roles in cell metabolism and signaling. Although...Full Text Available

2009-09-08

337

Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways  

UK PubMed Central (United Kingdom)

Melanoma is one of the most aggressive cancers, and its incidence is increasing. These tumors derive from the melanocyte lineage and remain incurable after metastasis. Here we report that SONIC HEDGEHOG...Full Text Available

2007-04-03

338

Measurements and elimination of Cherenkov light in fiber-optic scintillating detector for electron beam therapy dosimetry  

International Nuclear Information System (INIS)

In this study, a miniature fiber-optic radiation detector has been developed using a water-equivalent organic scintillator for electron beam therapy dosimetry. Usually, two kinds of light signals such as fluorescent and Cherenkov lights are generated in a fiber-optic radiation detector when a high-energy electron beam is irradiated. The fluorescent light signal is produced in the scintillator and is transmitted through a plastic optical fiber to a remote light-measuring device such as a PMT or a photodiode. The Cherenkov light could be also produced in the plastic optical fiber itself and be detected by a light-measuring device. Therefore, it could cause problems or limit the accuracy of the detection of a fluorescent light signal that is proportional to dose. The objectives of this study are to measure, characterize and eliminate Cherenkov light generated in a plastic optical fiber used as a component of a fiber-optic ...

2007-08-21

339

Maternal Overweight Programs Insulin and Adiponectin Signaling in the Offspring  

UK PubMed Central (United Kingdom)

Gestational exposure to maternal overweight (OW) influences the risk of obesity in adult life. Male offspring from OW dams gain greater body weight and fat mass and develop insulin resistance when fed...Full Text Available

2010-06-01

340

Mammalian target of rapamycin signaling modulates photic entrainment of the suprachiasmatic circadian clock  

UK PubMed Central (United Kingdom)

Inducible gene expression appears to be an essential event that couples light to entrainment of the master mammalian circadian clock located in the suprachiasmatic nucleus (SCN) of the hypothalamus....Full Text Available

2010-05-05

341

Male-derived cuticular hydrocarbons signal sperm competition intensity and affect ejaculate expenditure in crickets  

UK PubMed Central (United Kingdom)

Female sexual promiscuity can have significant effects on male mating decisions because it increases the intensity of competition between ejaculates for fertilization. Because sperm production is costly,...Full Text Available

2009-01-22

342

Macroscopic consequences of calcium signaling in microdomains: A first passage time approach  

CERN Document Server

Calcium (Ca) plays an important role in regulating various cellular processes. In a variety of cell types, Ca signaling occurs within microdomains where channels deliver localized pulses of Ca which activate a nearby collection of Ca-sensitive receptors. The small number of channels involved ensures that the signaling process is stochastic. The aggregate response of several thousand of these microdomains yields a whole-cell response which dictates the cell behavior. Here, we study analytically the statistical properties of a population of these microdomains in response to a trigger signal. We apply these results to understand the relationship between Ca influx and Ca release in cardiac cells. In this context, we use a first passage time approach to show analytically how Ca release in the whole cell depends on the single channel kinetics of Ca channels and the properties of microdomains. Using these results, we explain the ...

2007-01-01

343

Macropinocytosis is decreased in diabetic mouse macrophages and is regulated by AMPK  

UK PubMed Central (United Kingdom)

BackgroundMacrophages (MΦs) utilize macropinocytosis to integrate immune and metabolic signals in order to initiate an effective immune response. Diabetes is characterized...Full Text Available

344

Lnk controls mouse hematopoietic stem cell self-renewal and quiescence through direct interactions with JAK2  

UK PubMed Central (United Kingdom)

In addition to its role in megakaryocyte production, signaling initiated by thrombopoietin (TPO) activation of its receptor, myeloproliferative leukemia virus protooncogene (c-Mpl, or Mpl), controls...Full Text Available

2008-08-01

345

Lineage-specific co-evolution of the Egf receptor/ligand signaling system  

UK PubMed Central (United Kingdom)

BackgroundThe epidermal growth factor receptor (Egfr) with its numerous ligands has fundamental roles in development, cell differentiation and physiology. Dysfunction of the receptor-ligand...Full Text Available

346

Lessons in Signaling and Tumorigenesis from Polyomavirus Middle T Antigen  

UK PubMed Central (United Kingdom)

Summary: The small DNA tumor viruses have provided a very long-lived source of insights into many aspects of the life cycle of eukaryotic cells. In recent years, the emphasis has been on cancer-related...Full Text Available

2009-09-01

347

Interleukin-7 mediates glucose utilization in lymphocytes through transcriptional regulation of the hexokinase II gene  

UK PubMed Central (United Kingdom)

The cytokine interleukin-7 (IL-7) has essential growth activities that maintain the homeostatic balance of the immune system. Little is known of the mechanism by which IL-7 signaling regulates metabolic...Full Text Available

2010-06-01

348

Insulin receptor signaling in the development of neuronal structure and function  

UK PubMed Central (United Kingdom)

Sensory experience plays a crucial role in regulating neuronal shape and in developing synaptic contacts during brain formation. These features are required for a neuron to receive, integrate, and transmit...Full Text Available

349

Inhibition of Osteoclastogenesis by Mechanically Loaded Osteocytes: Involvement of MEPE  

UK PubMed Central (United Kingdom)

In regions of high bone loading, the mechanoresponsive osteocytes inhibit osteoclastic bone resorption by producing signaling molecules. One possible candidate is matrix extracellular phosphoglycoprotein...Full Text Available

2010-11-01

350

Inferring gene regulatory networks from asynchronous microarray data with AIRnet  

UK PubMed Central (United Kingdom)

BackgroundModern approaches to treating genetic disorders, cancers and even epidemics rely on a detailed understanding of the underlying gene signaling network. Previous work has...Full Text Available

351

Induced voltage in a shared corridor  

Energy Technology Data Exchange (ETDEWEB)

The induction of voltages on pipelines and railroad signal wires can be a problem when high-voltage transmission lines share the right of way. A handbook and two computer programs provide the analytic tools for utilities to avoid the problem.

1983-10-01

352

Independent Vector Analysis for Source Separation Using a Mixture of Gaussians Prior  

UK PubMed Central (United Kingdom)

Convolutive mixtures of signals, which are common in acoustic environments, can be difficult to separate into their component sources. Here we present a uniform probabilistic framework to separate...Full Text Available

2010-06-01

353

In vitro selection of RNA molecules that displace cocaine from the membrane-bound nicotinic acetylcholine receptor  

UK PubMed Central (United Kingdom)

The nicotinic acetylcholine receptor (AChR) controls signal transmission between cells in the nervous system. Abused drugs such as cocaine inhibit this receptor. Transient kinetic investigations indicate...Full Text Available

1998-11-24

354

In Vivo Reconstitution of ?-Secretase in Drosophila Results in Substrate Specificity?  

UK PubMed Central (United Kingdom)

The intramembrane aspartyl protease γ-secretase plays a fundamental role in several signaling pathways involved in cellular differentiation and has been linked with a variety of human diseases,...Full Text Available

2010-07-01

355

Identification of inhibitors of auxin transcriptional activation by means of chemical genetics in Arabidopsis  

UK PubMed Central (United Kingdom)

Auxin modulates diverse plant developmental pathways through direct transcriptional regulation and cooperative signaling with other plant hormones. Genetic and biochemical approaches have clarified...Full Text Available

2004-10-12

356

Identification of a Copper-Responsive Two-Component System on the Chromosome of Escherichia coli K-12  

UK PubMed Central (United Kingdom)

Using a genetic screen we have identified two chromosomal genes, cusRS (ylcA ybcZ), from Escherichia coli K-12 that encode a two-component, signal...Full Text Available

2000-10-01

357

Human intronic enhancers control distinct sub-domains of Gli3 expression during mouse CNS and limb development  

UK PubMed Central (United Kingdom)

BackgroundThe zinc-finger transcription factor GLI3 is an important mediator of Sonic hedgehog signaling and crucial for patterning of many aspects of the vertebrate body plan. In...Full Text Available

358

Glutamatergic regulation of ghrelin-induced activation of the mesolimbic dopamine system  

UK PubMed Central (United Kingdom)

Recently, we demonstrated that the central ghrelin signalling system, involving the ghrelin receptor (GHS-R1A), is important for alcohol reinforcement. Ghrelin targets a key mesolimbic circuit involved...Full Text Available

2011-01-01

359

Genetically-engineered mouse models for pancreatic cancer: Advances and current limitations  

UK PubMed Central (United Kingdom)

Recently, there has been significant progress in the development of genetically-engineered mouse (GEM) models. By introducing genetic alterations and/or signaling alterations of human pancreatic cancer...Full Text Available

2011-05-10

360

Generation and control of sound bullets with a nonlinear acoustic lens  

UK PubMed Central (United Kingdom)

Acoustic lenses are employed in a variety of applications, from biomedical imaging and surgery to defense systems and damage detection in materials. Focused acoustic signals, for example, enable ultrasonic...Full Text Available

2010-04-20

361

Gear fault detection using customized multiwavelet lifting schemes  

Science.gov (United States)

Fault symptoms of running gearboxes must be detected as early as possible to avoid serious accidents. Diverse advanced methods are developed for this challenging task. However, for multiwavelet transforms, the fixed basis functions independent of the input dynamic response signals will possibly reduce the accuracy of fault diagnosis. Meanwhile, for multiwavelet denoising technique, the universal threshold denoising tends to overkill important but weak features in gear fault diagnosis. To overcome the shortcoming, a novel method incorporating customized (i.e., signal-based) multiwavelet lifting schemes with sliding window denoising is proposed in this paper. On the basis of Hermite spline interpolation, various vector prediction and update operators with the desirable properties of biorthogonality, symmetry, short support and vanishing moments are constructed. The customized lifting-based multiwavelets for feature matching are chosen by the ...

2010-07-01

362

Frequently Asked ... - Precipitation Measurement Missions - NASA  

Science.gov (United States)

... say for sure if the signal is coming from hail, lots of graupel, or some other hydrometeor . ... Precipitation forms when cloud droplets or ice particles in clouds grow and .... A landslide is the movement of rock, debris, or earth down a slope. ...

363

Freeze-Dried Tendon Allografts as Tissue Engineering Scaffolds for Gdf5 Gene Delivery  

UK PubMed Central (United Kingdom)

Tendon reconstruction using grafts often results in adhesions that limit joint flexion. These adhesions are precipitated by inflammation, fibrosis, and paucity of tendon differentiation signals...Full Text Available

2008-03-01

364

FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis  

UK PubMed Central (United Kingdom)

Fibroblast growth factor (FGF) signaling is involved in skeletal development of the vertebrate. Gain-of-function mutations of FGF receptors (FGFR) cause craniosynostosis, premature fusion of the skull,...Full Text Available

2002-04-01

365

Evolutionary conservation of a microbody targeting signal that targets proteins to peroxisomes, glyoxysomes, and glycosomes  

UK PubMed Central (United Kingdom)

Peroxisomes, glyoxysomes, glycosomes, and hydrogenosomes have each been classified as microbodies, i.e., subcellular organelles with an electron-dense matrix that is bound by a single membrane. We investigated...Full Text Available

1991-09-01

366

Engineering ligand-responsive RNA controllers in yeast through the assembly of RNase III tuning modules  

UK PubMed Central (United Kingdom)

The programming of cellular networks to achieve new biological functions depends on the development of genetic tools that link the presence of a molecular signal to gene-regulatory activity. Recently,...Full Text Available

2011-07-01

367

Electrochemical detection of DNA hybridization based on silver-enhanced gold nanoparticle label  

Energy Technology Data Exchange (ETDEWEB)

An electrochemical detection method for analyzing sequence-specific DNA using gold nanoparticle DNA probes and subsequent signal amplification step by silver enhancement is described. The assay relies on the electrostatic adsorption of target oligonucleotides onto the sensing surface of the glassy carbon electrode (GCE) and its hybridization to the gold nanoparticle-labeled oligonucleotides DNA probe. After silver deposition onto gold nanoparticles, binding events between probe and target were monitored by the differential pulse voltammetry (DPV) signal of the large number of silver atoms anchored on the hybrids at the electrode surface. The signal intensity difference permits to distinguish between the match of two perfectly matched DNA strands and the near-perfect match where just one base pair was wrong. Coupled with this 'nanoparticle-promoted' reduction of silver signal ...

2002-10-03

368

Effects of metabotropic glutamate receptor 2/3 agonism and antagonism on schizophrenia-like cognitive deficits induced by phencyclidine in rats  

UK PubMed Central (United Kingdom)

Dysregulation of glutamate neurotransmission may play a role in cognitive deficits in schizophrenia. Manipulation of glutamate signaling using drugs acting at metabotropic glutamate receptors...Full Text Available

2010-08-10

369

Effects of ATRA combined with citrus and ginger-derived compounds in human SCC xenografts  

UK PubMed Central (United Kingdom)

BackgroundNF-κB is a survival signaling transcription factor complex involved in the malignant phenotype of many cancers, including squamous cell carcinomas (SCC). The citrus...Full Text Available

370

Editorial: EEG Phenomenology and Multiple Faces of Short-term EEG Spectral Pattern  

UK PubMed Central (United Kingdom)

An electroencephalogram (EEG) signal is extremely nonstationary, highly composite and very complex, all of which reflects the underlying integral neurodynamics. Understanding the EEG “grammar”,...Full Text Available

371

EGFR Signaling Through an Akt-SREBP-1-Dependent, Rapamycin-Resistant Pathway Sensitizes Glioblastomas to Anti-Lipogenic Therapy  

UK PubMed Central (United Kingdom)

Glioblastoma, the most common malignant brain tumor, is among the most lethal and difficult cancers to treat. Although epidermal growth factor receptor (EGFR) mutations are frequent in glioblastoma,...Full Text Available

372

Diurnal Variations of Mouse Plasma and Hepatic Bile Acid Concentrations as well as Expression of Biosynthetic Enzymes and Transporters  

UK PubMed Central (United Kingdom)

BackgroundDiurnal fluctuation of bile acid (BA) concentrations in the enterohepatic system of mammals has been known for a long time. Recently, BAs have been recognized as signaling...Full Text Available

373

Disruption of Bidirectional Oocyte-Cumulus Paracrine Signaling During In Vitro Maturation Reduces Subsequent Mouse Oocyte Developmental Competence1  

UK PubMed Central (United Kingdom)

Oocyte-cumulus cell bidirectional communication is essential for normal development of the oocyte and cumulus cells (CCs) within the follicle. We showed recently that addition of recombinant growth...Full Text Available

2009-05-01

374

Display unit of speedometer for automobile  

Energy Technology Data Exchange (ETDEWEB)

This patent describes a display unit of a speedometer for an automobile, comprising: a constant speed running circuit capable of producing output signals indicative of a desired car speed; an actual car speed operational circuit capable of producing output signals indicative of actual car speed; a comparing circuit for comparing the amplitudes of the output signals of the constant speed running operational circuit and the actual car speed operational circuit; bar graph decoders receiving the output signals from the constant speed running operational circuit and the actual car speed operational circuit; an EX-OR circuit having inputs coupled to respective bar graph decoders and having an output; and OR circuit having inputs coupled to respective bar graph decoders and having an output; selector means coupled to the output of the EX-OR circuit and the output of the OR circuit and controlled by an output ...

1987-03-03

375

Discrete molecular states in the brain accompany changing responses to a vocal signal  

UK PubMed Central (United Kingdom)

New experiences can trigger changes in gene expression in the brain. To understand this phenomenon better, we studied zebra finches hearing playbacks of birdsong. Earlier research had shown that initial...Full Text Available

2009-07-07

376

Developmental gene regulation during tomato fruit ripening and in-vitro sepal morphogenesis  

UK PubMed Central (United Kingdom)

BackgroundRed ripe tomatoes are the result of numerous physiological changes controlled by hormonal and developmental signals, causing maturation or differentiation of various fruit...Full Text Available

377

Development of small-molecule inhibitors of the group I p21-activated kinases, emerging therapeutic targets in cancer  

UK PubMed Central (United Kingdom)

The p21-activated kinases (PAKs), immediate downstream effectors of the small G-proteins of the Rac/cdc42 family, are critical mediators of signaling pathways regulating cellular behaviors and...Full Text Available

2010-09-01

378

Development of BWR core flow measurement technology using in-core neutron fluctuating signals  

Energy Technology Data Exchange (ETDEWEB)

The extensive work on the measurement technology of total and local flow rates in BWR core has been performed using in-core neutron fluctuating signals. Based on a large amount of actual data acquired from commercial BWR plants in operation, physical interpretation was discussed on the transit time of the neutron fluctuating signals. The new findings against the logical inconsistency of the transit time between the different LPRM detector positions lead to a promised core flow measurement algorithm using in-core neutron fluctuating signals. The advanced on-line core flow measurement system was developed and tested during the startup phase of the first ABWR. The measurement test results demonstrate the present core flow measurement system within the errors of 5 through 10% over the wide operating area besides the capability for the local void fraction and two-phase flow regime monitoring. (author)

1997-09-01

379

Detrended Fluctuation Analysis of Intracranial Pressure Predicts Outcome Following Traumatic Brain Injury  

UK PubMed Central (United Kingdom)

Detrended fluctuation analysis (DFA) is a recently developed technique suitable for describing scaling behavior of variability in physiological signals. The purpose of this study is to explore...Full Text Available

2008-11-01

380

Detection and Analysis of Tumor Fluorescence Using a Two-Photon Optical Fiber Probe  

UK PubMed Central (United Kingdom)

The utility of a two-photon optical fiber fluorescence probe (TPOFF) for sensing and quantifying tumor fluorescent signals was tested in vivo. Xenograft tumors were developed in athymic mice using MCA207...Full Text Available

2004-06-01

381

Dendritic Signals Command Firing Dynamics in a Mathematical Model of Cerebellar Purkinje Cells  

UK PubMed Central (United Kingdom)

AbstractDendrites of cerebellar Purkinje cells (PCs) respond to brief excitations from parallel fibers with lasting plateau depolarizations. It is unknown whether these plateaus are local...Full Text Available

2010-07-21

382

Deglutathionylation of 2-Cys Peroxiredoxin Is Specifically Catalyzed by Sulfiredoxin*  

UK PubMed Central (United Kingdom)

Reversible protein glutathionylation plays a key role in cellular regulation and cell signaling and protects protein thiols from hyperoxidation. Sulfiredoxin (Srx), an enzyme that catalyzes the reduction...Full Text Available

2009-08-28

383

Cytoplasmic Calcium Increases in Response to Changes in the Gravity Vector in Hypocotyls and Petioles of Arabidopsis Seedlings1  

UK PubMed Central (United Kingdom)

Plants respond to a large variety of environmental signals, including changes in the gravity vector (gravistimulation). In Arabidopsis (Arabidopsis thaliana) seedlings, gravistimulation...Full Text Available

2008-02-01

384

Cytokine signalling in rat pulp interstitial fluid and transcapillary fluid exchange during lipopolysaccharide-induced acute inflammation  

UK PubMed Central (United Kingdom)

The dental pulp consists of loose connective tissue encased in rigid dentinal walls. Because of its topography the tissue has low interstitial compliance and limited capacity to expand during fluid...Full Text Available

2006-05-15

385

Cyst Formation in Kidney via B-Raf Signaling in the PKD2 Transgenic Mice*  

UK PubMed Central (United Kingdom)

The pathogenic mechanisms of human autosomal dominant polycystic kidney disease (ADPKD) have been well known to include the mutational inactivation of PKD2. Although haploinsufficiency...Full Text Available

2009-03-13

386

Cyclic Diguanylate Signaling Proteins Control Intracellular Growth of Legionella pneumophila  

UK PubMed Central (United Kingdom)

Proteins that metabolize or bind the nucleotide second messenger cyclic diguanylate regulate a wide variety of important processes in bacteria. These processes include motility, biofilm formation, cell...Full Text Available

387

Cultural Variation in Vigilance and Precaution Themes.  

Science.gov (United States)

Determine the degree to which different precautionary themes are dominant in various target populations and how these themes are acquired. Assess cultural signals of potential danger: are there different kinds of potential danger in different cultures. Do...

2009-01-01

388

Conservation of spermatogonial stem cell self-renewal signaling between mouse and rat  

UK PubMed Central (United Kingdom)

Self-renewal of spermatogonial stem cells (SSCs) is the foundation for maintenance of spermatogenesis throughout life in males and for continuation of a species. The molecular mechanism underlying stem...Full Text Available

2005-10-04

389

Concurrent schedule control of human visual target fixations1  

UK PubMed Central (United Kingdom)

Operant conditioning techniques were applied to the study of how target fixations are controlled by the probability of signal occurrence. In a standard vigilance setting, gaze at three illuminable...Full Text Available

1973-11-01

390

Computer modelling of eddy current probes  

International Nuclear Information System (INIS)

Computer programs have been developed for modelling impedance and transmit-receive eddy current probes in two-dimensional axis-symmetric configurations. These programs, which are based on analytic equations, simulate bobbin probes in infinitely long tubes and surface probes on plates. They calculate probe signal due to uniform variations in conductor thickness, resistivity and permeability. These signals depend on probe design and frequency. A finite element numerical program has been procured to calculate magnetic permeability in non-linear ferromagnetic materials. Permeability values from these calculations can be incorporated into the above analytic programs to predict signals from eddy current probes with permanent magnets in ferromagnetic tubes. These programs were used to test various probe designs for new testing applications. Measurements of magnetic permeability in magnetically biased ferromagnetic materials have ...

1992-10-01

391

Computational promoter analysis of mouse, rat and human antimicrobial peptide-coding genes  

UK PubMed Central (United Kingdom)

BackgroundMammalian antimicrobial peptides (AMPs) are effectors of the innate immune response. A multitude of signals coming from pathways of mammalian pathogen/pattern recognition...Full Text Available

392

Comprehensive Quantification of Signal-to-Noise Ratio and g-Factor for Image-Based and k-Space-Based Parallel Imaging Reconstructions  

UK PubMed Central (United Kingdom)

Parallel imaging reconstructions result in spatially varying noise amplification characterized by the g-factor, precluding conventional measurements of noise from the final...Full Text Available

2008-10-01

393

Comparative study of nonlinear properties of EEG signals of normal persons and epileptic patients  

UK PubMed Central (United Kingdom)

BackgroundInvestigation of the functioning of the brain in living systems has been a major effort amongst scientists and medical practitioners. Amongst the various disorder of the...Full Text Available

394

Clarke's Column Neurons as the Focus of a Corticospinal Corollary Circuit  

UK PubMed Central (United Kingdom)

Proprioceptive sensory signals inform the CNS of the consequences of motor acts, but effective motor planning involves internal neural systems capable of anticipating actual sensory feedback....Full Text Available

2010-10-01

395

Chimeric Antigen Receptor Therapy for B-cell Malignancies  

UK PubMed Central (United Kingdom)

We presented data showing that the CART-19 cells expressing the 4-1BB signaling domain can have unprecedented and massive in-vivo expansion, traffic to tumor sites, persist long term in vivo, and induce...Full Text Available

396

Characterization of Terfestatin A, a New Specific Inhibitor for Auxin Signaling1[w  

UK PubMed Central (United Kingdom)

Terfestatin A (TrfA), terphenyl-β-glucoside, was isolated from Streptomyces sp. F40 in a forward screen for compounds that inhibit the expression of auxin-inducible...Full Text Available

2005-10-01

397

Characterization of ?-Butyrolactone Autoregulatory Signaling Gene Homologs in the Angucyclinone Polyketide WS5995B Producer Streptomyces acidiscabies?  

UK PubMed Central (United Kingdom)

Organisms belonging to the genus Streptomyces produce numerous important secondary metabolites and undergo a sophisticated morphological differentiation program. In many instances these...Full Text Available

2009-08-01

398

Chaotic system of two-phase flow in a small, horizontal, rectangular channel.  

Science.gov (United States)

Various measurement tools that are used in chaos theory were applied to analyze two-phase pressure signals with the objective of identifying and interpreting flow pattern transitions for two-phase flows in a small, horizontal rectangular channel. These me...

1995-01-01

399

Cells navigate with a local-excitation, global-inhibition-biased excitable network  

UK PubMed Central (United Kingdom)

Cells have an internal compass that enables them to move along shallow chemical gradients. As amoeboid cells migrate, signaling events such as Ras and PI3K activation occur spontaneously on pseudopodia....Full Text Available

2010-10-05

400

Calcium gradients and buffers in bovine chromaffin cells.  

UK PubMed Central (United Kingdom)

1. Digital imaging and photometry were used in conjunction with the fluorescent Ca2+ indicator, Fura-2, to examine intracellular Ca2+ signals produced by depolarization of single adrenal chromaffin...Full Text Available

1992-05-01

401

CID755673 enhances mitogenic signaling by phorbol esters, bombesin and EGF through a protein kinase D-independent pathway  

UK PubMed Central (United Kingdom)

Recently, CID755673 was reported to act as a highly selective inhibitor of protein kinase D (PKD). In the course of experiments using CID755673, we noticed that it exerted unexpected stimulatory...Full Text Available

2010-01-01

402

Bunyamwera virus can repair both insertions and deletions during RNA replication  

UK PubMed Central (United Kingdom)

The genomic termini of RNA viruses contain essential cis-acting signals for such diverse functions as packaging, genome translation, mRNA transcription, and RNA replication, and thus...Full Text Available

2010-06-01

403

Bump time-frequency toolbox: a toolbox for time-frequency oscillatory bursts extraction in electrophysiological signals  

UK PubMed Central (United Kingdom)

Backgroundoscillatory activity, which can be separated in background and oscillatory burst pattern activities, is supposed to be representative of local synchronies of neural assemblies....Full Text Available

404

Biomarkers Signal Contaminant Effects on the Organs of English Sole (Parophrys vetulus) from Puget Sound  

UK PubMed Central (United Kingdom)

Fish living in contaminated environments accumulate toxic chemicals in their tissues. Biomarkers are needed to identify the resulting health effects, particularly focusing on early changes at a subcellular...Full Text Available

2006-06-01

405

Bimodal MR-PET agent for quantitative pH imaging  

UK PubMed Central (United Kingdom)

Activatable or “smart” magnetic resonance contrast agents have relaxivities that depend on environmental factors such as pH or enzymatic activity, but the MR signal depends on...Full Text Available

2010-03-22

406

Behavioural assessment of pediatric pain  

UK PubMed Central (United Kingdom)

Behavioural assessment methods have been used to signal the need for intervention and to evaluate treatment effectiveness. Direct observation and rating scales have been used to assess pain and distress...Full Text Available

2009-01-01

407

Bacterial response to siderophore and quorum-sensing chemical signals in the seawater microbial community  

UK PubMed Central (United Kingdom)

BackgroundOceans are iron-deficient and nutrient-poor environments. These conditions impart limitations on our understanding of and our ability to identify microorganisms from the...Full Text Available

408

Autoantibodies to BRAF, a new family of autoantibodies associated with rheumatoid arthritis  

UK PubMed Central (United Kingdom)

IntroductionBRAF (v raf murine sarcoma viral oncogene homologue B1) is a serine-threonine kinase involved in the mitogen-activated protein kinase (MAPK) signalling pathway, known...Full Text Available

2010-01-01

409

Atrial natriuretic peptide signal pathway upregulated in stomach of streptozotocin-induced diabetic mice  

UK PubMed Central (United Kingdom)

AIM: To investigate atrial natriuretic peptide (ANP) secretion from gastric mucosa and the relationship between the ANP/natriuretic peptide receptor type A (NPR-A) pathway and diabetic gastroparesis.METHODS:...Full Text Available

2010-01-07

410

Arabidopsis and Tobacco SUPERMAN regulate hormone signalling and mediate cell proliferation and differentiation  

UK PubMed Central (United Kingdom)

Arabidopsis thaliana SUPERMAN (SUP) plays an important role during flower development by maintaining the boundary between stamens and carpels in the inner two whorls....Full Text Available

2011-01-01

411

All-optical synchronization of a 40GHz self-pulsating distributed Bragg reflector laser to return-to-zero 10, 20 and 40Gbit/s data streams  

British Library Electronic Table of Contents (United Kingdom)

This paper presents experimental investigations of the all-optical synchronization of a distributed Bragg reflector (DBR) laser self-pulsating at 40GHz on various injected bit-rate signals. Even though there is no modulation applied to this laser, it exhibits a modulation of its output emission, measured at 39.7GHz with a linewidth of 30MHz. Such performance is exploited in all-optical clock recovery for a return-to-zero data stream at 40Gbit/s. The SP-DBR laser wavelength and the injected signal wavelength are 10nm apart. All-optical synchronization is demonstrated at 40Gbit/s with a linewidth of less than 20MHz for injected signals at 10 and 20Gbit/s, respectively. Thus the SP-DBR laser proves to be very versatile and can be synchronized on various bit-rate data signals.

2009-01-01

412

Ageing in Drosophila: The role of the insulin/Igf and TOR signalling network  

UK PubMed Central (United Kingdom)

A remarkable discovery of recent years is that, despite the complexity of ageing, simple genetic interventions can increase lifespan and improve health during ageing in laboratory animals. The pathways...Full Text Available

2011-05-01

413

Activity-Dependent Augmentation of Spontaneous Neurotransmission during Endoplasmic Reticulum Stress  

UK PubMed Central (United Kingdom)

The endoplasmic reticulum (ER) is an essential cellular compartment responsible for Ca2+ sequestration, signaling, protein translation, folding as well as transport. Several acute...Full Text Available

2010-05-26

414

Activated PPAR? Targets Surface and Intracellular Signals That Inhibit the Proliferation of Lung Carcinoma Cells  

UK PubMed Central (United Kingdom)

Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors belonging to the nuclear hormone receptor superfamily. Their discovery in the 1990s provided insights...Full Text Available

2008-01-01

415

Actin Fusion Proteins Alter the Dynamics of Mechanically Induced Cytoskeleton Rearrangement  

UK PubMed Central (United Kingdom)

Mechanical forces can regulate various functions in living cells. The cytoskeleton is a crucial element for the transduction of forces in cell-internal signals and subsequent biological responses. Accordingly,...Full Text Available

416

Aberrant repair and fibrosis development in skeletal muscle  

UK PubMed Central (United Kingdom)

The repair process of damaged tissue involves the coordinated activities of several cell types in response to local and systemic signals. Following acute tissue injury, infiltrating inflammatory cells...Full Text Available

417

AMP-activated protein kinase (AMPK) cross-talks with canonical Wnt signaling via phosphorylation of ?-catenin at Ser 552  

UK PubMed Central (United Kingdom)

AMP-activated protein kinase (AMPK) is a key regulator of energy metabolism; its activity is regulated by a plethora of physiological conditions, exercises and many anti-diabetic drugs. Recent...Full Text Available

2010-04-23

418

ALTERATION OF THE PKC-MEDIATED SIGNALING PATHWAY FOR SMOOTH MUSCLE CONTRACTION IN OBSTRUCTION-INDUCED HYPERTROPHY OF THE URINARY BLADDER  

UK PubMed Central (United Kingdom)

Normal urinary bladder function requires contraction and relaxation of the detrusor smooth muscle (DSM). The DSM undergoes compensatory hypertrophy in response to partial bladder outlet obstruction...Full Text Available

2009-07-01

419

A novel fluorescent pH probe for expression in plants  

UK PubMed Central (United Kingdom)

BackgroundThe pH is an important parameter controlling many metabolic and signalling pathways in living cells. Recombinant fluorescent pH indicators (pHluorins) have come into vogue...Full Text Available

420

A novel Na+ channel splice form contributes to the regulation of an androgen-dependent social signal  

UK PubMed Central (United Kingdom)

Na+ channels are often spliced but little is known about the functional consequences of splicing. We have been studying the regulation of Na+ current inactivation in an...Full Text Available

2008-09-10

421

A discrete cell model with adaptive signalling for aggregation of Dictyostelium discoideum.  

UK PubMed Central (United Kingdom)

Dictyostelium discoideum (Dd) is a widely studied model system from which fundamental insights into cell movement, chemotaxis, aggregation and pattern formation can be gained. In this system aggregation...Full Text Available

1997-03-29

422

A direct role for serum albumin in the cellular uptake of long-chain fatty acids.  

UK PubMed Central (United Kingdom)

The interaction of long-chain fatty acids with cells is important for their uptake and metabolism, as well as their involvement in signalling processes. The majority of long-chain fatty acids circulating...Full Text Available

1995-05-15

423

A Review on Sensor, Signal, and Information Processing ...  

Science.gov (United States)

... Rep. ISIS-04-504, Institute for Software Integrated Systems (2004). [59] G. Simon, M. Maroti, A. Ledeczi, G. Balogh, B. Kusy, A. Nadas, G. Pap, J ...

2011-05-15

424

A Mitochondrial Superoxide Signal Triggers Increased Longevity in Caenorhabditis elegans  

UK PubMed Central (United Kingdom)

The nuo-6 and isp-1 genes of C. elegans encode, respectively, subunits of complex I and III of the mitochondrial respiratory chain. Partial loss-of-function...Full Text Available

2010-12-01

425

A Decline in p38 MAPK Signaling Underlies Immunosenescence in Caenorhabditis elegans  

UK PubMed Central (United Kingdom)

The decline in immune function with aging, known as immunosenescence, has been implicated in evolutionarily diverse species, but the underlying molecular mechanisms are not understood. During aging...Full Text Available

2011-05-01

426

A Conserved Role for Phosphoinositide-3-Kinase but Not Akt Signaling in Mitochondrial Adaptations that Accompany Physiological Cardiac Hypertrophy  

UK PubMed Central (United Kingdom)

Physiological cardiac hypertrophy is associated with mitochondrial adaptations that are characterized by activation of PGC-1α and increased fatty acid oxidative (FAO) capacity. It is...Full Text Available

2007-10-01

427

?Activation of the mitogen-activated protein kinase pathways by heat shock  

UK PubMed Central (United Kingdom)

In addition to inducing new transcriptional activities that lead within a few hours to the accumulation of heat shock proteins (Hsps), heat shock activates within minutes the major signaling transduction...Full Text Available

2002-04-01

428

Oil turbulence in the next decade. An essay on high oil prices in a supply-constrained world  

International Nuclear Information System (INIS)

A CIEP analysis of the recent development of demand and supply for crude oil indicates that the mismatch in supply and demand growth could cause tighter oil markets than we already experience today. In the World Energy Outlook 2007, the International Energy Agency (IEA) warned of a possible 'energy crunch'. But what was anticipated to happen in the first part of the next decade has been fast-forwarded to today, more than 5 years earlier, and could shake the very foundation of our energy systems if no action is undertaken. Without exaggeration, the recent developments in the international oil market are ground-breaking: a little over a year ago, in January 2007, the West Texas Intermediate crude oil price (WTI) traded for USD50 dollar a barrel. Within a year, the price doubled to USD100 per barrel in January 2008 and pushed through to over USD135 in June 2008, against the backdrop of the fresh market supposition about reaching a whopping USD200 per barrel in 2009. ...

429

Condition monitoring and thermoeconomic optimization of operation for a hybrid plant using artificial neural networks; Tillstaandsoevervakning och termoekonomisk driftoptimering av en hybridanlaeggning med artificiella neurala naetverk  

Energy Technology Data Exchange (ETDEWEB)

The project aim is to model the hybrid plant at Vaesthamnsverket in Helsingborg using artificial neural networks (ANN) and integrating the ANN models, for online condition monitoring and thermoeconomic optimization, at Vaesthamnsverket. The definition of a hybrid plant is that it uses more than one fuel, in this case a natural gas fuelled gas turbine with heat recovery steam generator (HRSG) and a biomass fuelled steam boiler with steam turbine. The project is a continuation of previous projects where ANN training was done with operational data from the plant. The ANN models have, if required, been updated to better suit the purpose of this project. The thermoeconomic optimization takes into account current electricity prices, taxes, fuel prices etc. and calculates the current production cost along with the 'predicted' production cost. The tool also has a built in feature of predicting when a compressor wash is economically beneficial. The user interface is developed ...

2007-12-15

430

Use of integrin-linked kinase to extend function of encapsulated pancreatic tissue  

Energy Technology Data Exchange (ETDEWEB)

We have studied the impact of overexpression of an intracellular signaling protein, integrin-linked kinase (ILK), on the survival and function of encapsulated islet tissue used for the treatment of type 1 diabetes. The dimensions of the encapsulated tissue can impact the stresses placed on the tissue and ILK overexpression shows the ability to extend function of dissociated cells as well as intact islets. These results suggest that lost cell-extracellular matrix interactions in cell encapsulation systems can lead to decreased insulin secretion and ILK signaling is a target to overcome this phenomenon. (communication)

2010-12-15

431

Self-seeded injection-locked FEL amplifier  

Energy Technology Data Exchange (ETDEWEB)

A self-seeded free electron laser (FEL) provides a high gain and extraction efficiency for the emitted light. An accelerator outputs a beam of electron pulses to a permanent magnet wiggler having an input end for receiving the electron pulses and an output end for outputting light and the electron pulses. An optical feedback loop collects low power light in a small signal gain regime at the output end of said wiggler and returns the low power light to the input end of the wiggler while outputting high power light in a high signal gain regime.

1998-12-01

432

Researches on gear fault diagnosis techniques  

Science.gov (United States)

Seeking effective methods is one of the most important goals in machinery fault diagnosis. The effective methods for gear fault diagnosis have been successively developed in our Institute. This paper is a comprehensive treatise based on our research work of recent years. A mathematical model of vibration signals for defective gears is physically described. Five effective new methods for gear fault diagnosis, such as zoom complex envelope analysis, wideband demodulation technique, bispectrum analysis, correlative spectrum analysis, and maximum entropy spectrum analysis for phase modulated signals, are summarily presented. The listed illustrations prove sufficiently the validation of these methods.

1993-05-01

433

Reciprocal regulation of the neural and innate immune systems  

British Library Electronic Table of Contents (United Kingdom)

Innate immune responses are regulated by microorganisms and cell death, as well as by a third class of stress signal from the nervous and endocrine systems. The innate immune system also feeds back, through the production of cytokines, to regulate the function of the central nervous system (CNS), and this has effects on behaviour. These signals provide an extrinsic regulatory circuit that links physiological, social and environmental conditions, as perceived by the CNS, with transcriptional 'decision-making' in leukocytes. CNS-mediated regulation of innate immune responses optimizes total organism fitness and provides new opportunities for therapeutic control of chronic infectious, inflammatory and neuropsychiatric diseases.

2011-01-01

434

Production of four-weak-bosons and heavy Higgs signals in TeV photon-photon collisions  

Energy Technology Data Exchange (ETDEWEB)

We have studied the signals for a heavy Higgs boson in the processes {gamma}{gamma}{yields}WWWW, and {gamma}{gamma}{yields}WWZZ at a photon linear collider. The results are based on the first complete tree-level calculation for these reactions. We show that, with a forward ``spectator`` W tag, and a central ``spectator`` W veto to suppress backgrounds from transverse W, Z production, the invariant mass spectrum of central WW, ZZ pairs is sensitive to Higgs bosons with a mass up to 1 TeV in a 2-TeV linear collider. ((orig.)).

1995-02-01

435

Observation of stochastic resonance near a subcritical bifurcation  

Energy Technology Data Exchange (ETDEWEB)

A hysteretic subcritical period-doubling bifurcation is observed in the nonlinear strain dynamics of a magnetostrictive oscillator. The dynamic strain response of the magnetostrictive oscillator was observed with a high-resolution fiber optic interferometer. The effects of low-frequency modulation and band-limited stochastic fluctuations on such a bifurcation are investigated. Power spectral density measurements show that for an optimal value of externally injected noise the signal-to-noise ratio of a low-frequency modulation signal is enhanced by greater than 14 dB, thus indicating the first experimental observation of stochastic resonance near a bistable period-doubling bifurcation. 10 refs., 7 figs.

1993-01-01

436

Micropulse Lidar (MPL) Handbook  

Energy Technology Data Exchange (ETDEWEB)

The micropulse lidar (MPL) is a ground-based optical remote sensing system designed primarily to determine the altitude of clouds overhead. The physical principle is the same as for radar. Pulses of energy are transmitted into the atmosphere; the energy scattered back to the transceiver is collected and measured as a time-resolved signal. From the time delay between each outgoing transmitted pulse and the backscattered signal, the distance to the scatterer is infered. Besides real-time detection of clouds, post-processing of the lidar return can also characterize the extent and properties of aerosol or other particle-laden regions.

2006-05-01

437

Method for limiting scram discharge water  

International Nuclear Information System (INIS)

Object: To limit the discharge amount of reactor water in a primary system at the time of scram to prevent excessive outflow of reactor water outside the system. Structure: A signal from an upper limit position indicator detects the fact that control rods are completely inserted when the reactor is urgently stopped and the detection signal causes a valve in an outflow line of the discharge water from a control rod driving mechanism to be closed to limit the amount of discharge flown into the scram discharge vessel, thus preventing outflow of reactor water in the primary system after the scram has been initiated. (Kamimura, M.).

438

Method and system for controlling the idle speed of an internal combustion engine at variable ignition timing  

Energy Technology Data Exchange (ETDEWEB)

The idle speed of an internal combustion engine is controlled in response to a variable ignition timing control signal from a microcomputer. The microcomputer derives this control signal as a function of the magnitude of engine speed variation which occurs during engine idle periods to cause the ignition timing to vary quickly in response to a transitory engine load variation. An auxiliary air delivery system may be advantageously incorporated in the idle speed control system to cooperate with the ignition timing control in response to the engine speed variation.

1984-05-08

439

Feedwater control device of the steam generator in an atomic power station  

International Nuclear Information System (INIS)

Purpose: In a case of automatically controlling the water level at the time of generating a lower power, to impact the followability of the control necessary for the power variation of the steam generator thereby to obtain good controllability. Constitution: A signal of deviation of water level of a steam generator and its set value and a signal of a difference between the temperature of the primary coolant in the high temperature side pipeline and that of the primary coolant in the low temperature side pipeline are used to automatically or manually control the flow quantity of water fed to the steam generator. (Yoshihara, H.).

440

Detection of EDM defects under Monju support plate using experimental data from remote field eddy current probes and a multi-frequency algorithm  

International Nuclear Information System (INIS)

This paper describes detection of electro-discharged machine (EDM) defects in magnetic steam generator (SG) tubes of Monju fast breeder reactor (FBR). The EDM defects are located under support plate (SP), on the outer tube surface and they are detected by a remote field eddy current probe. Using the experimental measurements and a multi frequency algorithm, the defect signal can be extracted from the SP signal. The parameters of the multi-frequency algorithm were calculated by comparing SP measurements with two-dimensional finite element simulations (FEM). (author)

2006-07-01

441

Convective heat transfer under unsteady impinging jets: the effect of the shape of the unsteadiness  

Science.gov (United States)

Unsteady impinging jets are systematically controlled with respect to their time dependence in order to investigate the influence of unsteadiness on the heat transfer performance. This is achieved by a special mass flow control device, which allows almost arbitrary shapes of unsteadiness to be imposed onto the impinging jet. Three different standard signals (sinusoidal, triangular, rectangular) and two specially designed signals are applied and their influence on heat transfer is determined in terms of an enhancement factor. Heat transfer augmentation up to 30% was found and could be physically explained with the help of PIV and hot-wire measurements of the flow field.

2009-10-01

442

Bragg-curve spectroscopy detector  

Energy Technology Data Exchange (ETDEWEB)

In an ionization chamber with the electric field parallel to the particle trajectories, the time dependence of the anode signal contains all the information about the energy and the nuclear charge of the ionizing particle. By proper pulse shaping with a long and a short time constant the total ionization charge and the ionization charge integrated around the Bragg maximum, respectively, can be obtained. The former signal is proportional to the total energy, whereas the latter allows the nuclear charge to be deduced directly. An energy resolution of 0.4% and a Z resolution ..delta..Z/Z = 1/82 was achieved for 130 MeV /sup 32/S ions and argon-methane as the stopping medium.

1982-02-01

443

An Explanation of the CDF Dijet Anomaly within a $U(1)_X$ Stueckelberg Extension  

CERN Document Server

We discuss the recent excess seen by the CDF Collaboration in the dijet invariant mass distribution produced in association with a $W$ boson. We analyze the possibility of such a signal within the context of a $U(1)_X$ Stueckelberg extension of the Standard Model where the new gauge boson couples only to quarks. In addition to the analysis of the $Wjj$ anomaly we also discuss the production of $Zjj$ and $\\gamma jj$ at the Tevatron. The analysis is then extended to the Large Hadron Collider with $\\sqrt{s}=7 {\\rm TeV}$ and predictions for the dijet signals are made.

2011-01-01

444

A new method for the analysis of infrared stimulated luminescence data from potassium feldspars  

International Nuclear Information System (INIS)

A new method is described for the analysis of high precision pulse annealing data obtained using IRSL measurements on potassium feldspars using a Risoe reader. Presenting the data as the percentage of the signal lost per annealing phase permits more detailed comparisons to be made between samples. In addition, it is possible to directly compare the temperatures at which the TL and IRSL signals are released, thus giving information about the relationship between them. This method of analysis is applied to pulse annealing data for natural, irradiated, preheated and IR bleached aliquots. (author).

1993-07-01

445

A multiple sampling proportional counter for particle identification of relativistic heavy ions  

Energy Technology Data Exchange (ETDEWEB)

A multiple sampling dE/dx counter using a multiwire proportional chamber equipped with catbode pads was constructed for the multiple detection of dE/dx values along a particle trajectory. For low-energy particles this counter was proved to be useful as a Bragg-curve detector. At relativistic energies around E=14.6 GeV/nucleon good particle identification was obtained by cathode pad signals as well as anode signals for the range of projectile fragments from Z=1 (minimum ionization) up to a beam charge of Z=14. (orig.).

1990-11-15

446

A driving system for Moessbauer spectrometer  

International Nuclear Information System (INIS)

The driving system of a Moessbauer spectrometer is described. The system comprises a minivibrator, a digital generator of the reference velocity signal, and circuits for controlling the vibrator. The reference velocity signal is stored by the control computer in an intermediate storage. The feedback in the control circuits includes correction for nonlinearity of the driving facility. A Moessbauer spectrometer which is equipped with this driving system exhibits a velocity scale nonlinearity below 0.1%. The resonance line width for sodium nitroprusside is 0.27 #+-# 0.01 mm/s. (author). 6 figs., 8 refs.

447

Hypercapnic normalization of BOLD fMRI: comparison across field strengths and pulse sequences.  

DEFF Research Database (Denmark)

The blood oxygenation level-dependent (BOLD) functional magnetic resonance imaging (fMRI) signal response to neural stimulation is influenced by many factors that are unrelated to the stimulus. These factors are physiological, such as the resting venous cerebral blood volume (CBV(v)) and vessel size, as well as experimental, such as pulse sequence and static magnetic field strength (B(0)). Thus, it is difficult to compare task-induced fMRI signals across subjects, field strengths, and pulse sequences. This problem can be overcome by normalizing the neural activity-induced BOLD fMRI response by a global hypercapnia-induced BOLD signal. To demonstrate the effectiveness of the BOLD normalization approach, gradient-echo BOLD fMRI at 1.5, 4, and 7 T and spin-echo BOLD fMRI at 4 T were performed in human subjects. For neural stimulation, subjects performed sequential finger movements at 2 Hz, while for global stimulation, ...

2004-01-01

448

Wind turbine fault diagnosis based on Morlet wavelet transformation and Wigner-Ville distribution  

Energy Technology Data Exchange (ETDEWEB)

Based on the Morlet wavelet transformation and Wigner-Ville distribution (WVD), we present a wind turbine fault diagnosis method in this paper. Wind turbine can be damaged by moisture absorption, fatigue, wind gusts or lightening strikes. Due to this reason, there is an increasing need to monitor the health of these structures. Vibration analysis is the best-known technology applied in wind turbine condition monitoring, in which the time-frequency analysis techniques such as Wigner-Ville distribution (WVD) are widely used. Theoretically WVD has an infinite resolution in time-frequency domain. For early wind turbine fault signals, however, there are two main difficulties in WVD analysis. One is strong noise signals in the background and the other is cross terms in WVD itself. In this paper, continuous wavelet transformation (CWT) is employed to filter useless noise in raw vibration signals, and auto terms window (ATW) ...

2010-12-15

449

Quantitative imaging of turbulent and reacting flows  

Energy Technology Data Exchange (ETDEWEB)

Quantitative digital imaging, using planar laser light scattering techniques is being developed for the analysis of turbulent and reacting flows. Quantitative image data, implying both a direct relation to flowfield variables as well as sufficient signal and spatial dynamic range, can be readily processed to yield two-dimensional distributions of flowfield scalars and in turn two-dimensional images of gradients and turbulence scales. Much of the development of imaging techniques to date has concentrated on understanding the requisite molecular spectroscopy and collision dynamics to be able to determine how flowfield variable information is encoded into the measured signal. From this standpoint the image is seen as a collection of single point measurements. The present effort aims at realizing necessary improvements in signal and spatial dynamic range, signal-to-noise ratio and spatial resolution in the ...

1993-12-01

450

Empirical Evaluation of a New Method for Calculating Signal to Noise Ratio (SNR) for Microarray Data Analysis  

Energy Technology Data Exchange (ETDEWEB)

Signal-to-noise-ratio (SNR) thresholds for microarray data analysis were experimentally determined with an oligonucleotide array that contained perfect match (PM) and mismatch (MM) probes based upon four genes from Shewanella oneidensis MR-1. A new SNR calculation, called signal to both standard deviations ratio (SSDR) was developed, and evaluated along with other two methods, signal to standard deviation ratio (SSR), and signal to background ratio (SBR). At a low stringency, the thresholds of SSR, SBR, and SSDR were 2.5, 1.60 and 0.80 with oligonucleotide and PCR amplicon as target templates, and 2.0, 1.60 and 0.70 with genomic DNA as target templates. Slightly higher thresholds were obtained at the high stringency condition. The thresholds of SSR and SSDR decreased with an increase in the complexity of targets (e.g., target types), and the presence of background DNA, and a decrease in the composition ...

2008-03-06

451

Electrochemical noise measurements of sustained microbially influenced pitting corrosion in a laboratory flow loop system.  

Energy Technology Data Exchange (ETDEWEB)

Because of the chaotic nature of the corrosion process and the complexity of the electrochemical noise signals that are generated, there is no generally accepted method of measuring and interpreting these signals that allows the consistent detection and identification of sustained localized pitting (SLP) as compared to general corrosion. We have reexamined electrochemical noise analysis (ENA) of localized corrosion using different hardware, signal collection, and signal processing designs than those used in conventional ENA techniques. The new data acquisition system was designed to identify and monitor the progress of SLP by analyzing the power spectral density (PSD) of the trend of the corrosion current noise level (CNL) and potential noise level (PNL). Each CNL and PNL data point was calculated from the root-mean- square value of the ac components of current and potential fluctuation ...

1999-01-13

452

Comparison of turbo inversion recovery magnitude (TIRM) with T2-weighted turbo spin-echo and T1-weighted spin-echo MR imaging in the early diagnosis of acute osteomyelitis in children  

Energy Technology Data Exchange (ETDEWEB)

Objective. To compare turbo inversion recovery magnitude (TIRM) with standard T1-weighted (T1-W) and T2-weighted (T2-W) MR sequences in the very early detection of acute osteomyelitis in children. Materials and methods. In 15 children with osteomyelitis, 15 sets of T1-W spin-echo (SE) (TR/TE, 400-640/12-17), T2-W turbo spin-echo (TSE) (TR/TE/ETL, 3290-4465/112-120/11), and TIRM (TR/TE/TI, 4000-6120/60/160) images were acquired with a 1.0-T magnet. Contrast-to-noise (C/N) ratios and percentage of signal between lesion and normal bone marrow were analysed with a computer-assisted image analysing system in a region of interest (ROI). Results. In 13 of 15 patients, the absolute signal enhancement in a ROI on the TIRM images was better than on the T1-W SE and T2-W TSE images and in 14 of 15 cases, C/N ratios were also better on the TIRM images than on the other sequences. In the other cases, the TIRM signal was diagnostically ...

1998-11-01

453

Why Gabor Frames? Two Fundamental Measures of Coherence and Their Role in Model Selection  

CERN Document Server

The problem of model selection arises in a number of contexts, such as subset selection in linear regression, estimation of structures in graphical models, and signal denoising. This paper generalizes the notion of "incoherence" in the existing literature on model selection and introduces two fundamental measures of coherence---termed as the worst-case coherence and the average coherence---among the columns of a design matrix. It utilizes these two measures of coherence to provide an in-depth analysis of two variants of a simple one-step thresholding (OST) algorithm for model selection and proves that OST is feasible for model selection as long as the design matrix obeys an easily verifiable property. One of the key insights offered by the ensuing analysis in this regard is that if the design matrix has reasonably small worst-case and average coherence then OST performs near-optimally when either (i) the energy of any nonzero entry of the ...

2010-01-01

454

Void signal analysis and gas-liquid two-phase flow regime determination by a statistical pattern recognition method  

International Nuclear Information System (INIS)

A statistical pattern recognition method was applied to the analysis of the signals of crosssectional mean void fraction for discriminating gas-liquid two-phase flow regimes. The analysis and discrimination were carried out based on six key flow patterns : bubble, cap-bubble, plug, froth (F_I and F_I_I), and annular flow. For each flow condition 100 void signals with a recording dimension of 1 second were used and transferred to discrete data, the sampling frequency of which was selected at 100 Hz by comparison between correct recognition rates obtained from different frequencies. The magnitude of the time-averaged void fraction was partly employed supplementary to the pattern recognition method. The boundaries between the six flow regimes were determined corresponding to a correct recognition rate of 80 % and drawn on a superficial gas-liquid velocities diagram. These flow boundaries were also compared with those available in the literature. ...

1986-01-01

455

Vibration test report on the instrumented capsule for fuel irradiation test  

Energy Technology Data Exchange (ETDEWEB)

The fluid-induced vibration level of instrumented capsule, which was manufactured for fuel irradiation test at the reactor core of HANARO, was investigated. For this purpose, the instrumented capsule was loaded at the OR site of the HANARO design verification test facility that could simulate identical flow condition as the HANARO core. Then, vibration signals of the instrumented capsule subjected to various flow conditions were measured by using vibration sensors. In time domain analysis, maximum amplitudes and RMS values of the measured acceleration and displacement signals were obtained. By using frequency domain analysis, frequency components of the fluid-induced vibration were analyzed. In addition, natural frequencies of the instrumented capsule were obtained by performing modal test. The frequency analysis results showed that the natural frequency components near 7.5Hz and 17.5Hz were dominant in the fluid-induced vibration ...

2003-01-01

456

Study to reduce laser-induced breakdown spectroscopy measurement uncertainty using plasma characteristic parameters  

Energy Technology Data Exchange (ETDEWEB)

Using standard brass alloy samples, an approach to reduce the laser-induced breakdown spectroscopy measurement uncertainty was tested and proved. Two important parameters for plasma characterization, the plasma temperature and the electron density, were applied to minimize the signal uncertainties due to uncontrollable experimental parameter variations. Results show that for the pulse-to-pulse analysis, the signal fluctuations can be significantly reduced by utilizing the plasma characteristic information. The major source for the single pulse fluctuations is the redistribution of the characteristic line at different temperatures according to the Boltzmann distribution under LTE. The change of the degree of ionization also contributes to the signal fluctuations. For the multi-pulse analysis, due to the nonlinear relationship between the plasma temperature and the line intensity, it is not applicable to utilize the Boltzmann ...

2010-07-15

457

Study of core collapse neutrino signals and constraints on neutrino masses from a future Galactic Supernova  

CERN Document Server

We study the sensitivity to neutrino masses of a Galactic supernova neutrino signal as could be measured with the detectors presently in operation and with future large volume water \\v{C}erencov and scintillator detectors. The analysis uses the full statistics of neutrino events. The method proposed uses the principles of Bayesian inference reasoning and has shown a remarkably independence of astrophysical assumptions. We show that, after accounting for the uncertainties in the detailed astrophysical description of the neutrino signal and taking into account the effects of neutrino oscillations in the supernova mantle, detectors presently in operation can have enough sensitivity to reveal a neutrino mass (or to set upper limits) at the level of 1 eV. This is sensibly better than present results from tritium $\\beta$-decay experiments, competitive with the most conservative limits from neutrinoless double $\\beta$-decay and less precise but ...

2005-01-01

458

Spectral energy effects in ESR bone dosimetry: photons and electrons  

International Nuclear Information System (INIS)

The spectral energy-dependence of the radiation-induced ESR signal has been studied in ovine cortical bone. Crushed bone samples were irradiated using photon beams with effective energies in the range from 0.06 to 6 MeV, and electron beams with mean energies in the range from 2 to 10 MeV. The photon and electron data were normalized to a dose to bone of 50 Gy and the results are reported as response relative to the ESR signal for photon irradiation at 1.25 MeV ("6"0Co). The photon irradiation results show that the ESR response is greatest at low energies with a relative value of 1.2 at 0.06 MeV. The relative response decreases, as the energy increases, to approximately 0.85 in the region of 2 to 3 MeV. These variations in the relative ESR responses are significantly less than the ESR energy-dependent responses reported in the literature for human tooth enamel and synthetic hydroxyapatite. An explanation for this difference is offered. For ...

459

Spectral dependence of ultrasonic attenuation for hydrided Zr-2.5%Nb Alloy  

International Nuclear Information System (INIS)

The cold-worked Zr-2.5%Nb alloy is used as material for the pressure tubes in CANDU nuclear reactors. During the service life in reactor, diffusion of hydrogen and/or deuterium in the pressure tubes wall occur. Below a certain temperature, a stable hydride of zirconium is formed, as a brittle phase which can lead to catastrophic failures. For this reason, it is very important to be able to investigate the hydrogen effect on the micro structural properties of zirconium alloys. In the present paper a non-destructive testing technique is used, known as ultrasonic spectral analysis. When an ultrasonic signal traverses a medium, the frequency components associated with the input signal are altered. By frequency analysing the reflected signals, it is possible to study and compare the material properties. The two major parameters measured in ultrasonic spectroscopy are the attenuation and the velocity of the waves. Attenuation is ...

2009-10-12

460

Sodium leak detector  

International Nuclear Information System (INIS)

Purpose: To permit accurate detection of sodium leakage by distinguishing between variations in the overflow tank level due to changes in sodium temperature accompanying changes in the power level or operating state of a liquid metal sodium cooled fast breeder, and a reduction in power level due to duct leakage. Constitution: The volume of sodium in the primary cooling system is roughly estimated from the temperatures of hot and cold legs, and the duct leak preset level with respect to the sodium liquid level within an overflow tank when the plant is normal is varied according to the state of the plant. More particularly, the volume of sodium within the overflow tank is calculated on the basis of a signal representing the liquid level detected by a liquid level gauge in the overflow tank and a signal representing the temperature detected by hot leg and cold leg thermometers, thereby obtaining the preset value of the liquid level within the ...

461

Prediction of the intramuscular fat content in loin muscle of pig carcasses by quantitative time-resolved ultrasound  

British Library Electronic Table of Contents (United Kingdom)

A novel method for non-destructive intramuscular fat (IMF) estimation via spectral ultrasound backscatter analysis of signals obtained from pig carcasses early post mortem is described. A commercial hand-held ultrasound device (center frequency: 2.7MHz) was modified to focus the sound beam to the longissimus muscle at the 2nd/3rd last rib. Time-resolved ultrasound backscatter signals of loin muscle were recorded 45minp.m. on 82 pig carcass sides. Backfat width (d"B"F=18.9+/-3.8mm) and muscle attenuation (@a"m"u"s"c"l"e=.77+/-.15dBMHz^-^1cm^-^1) were assessed from the measured pulse echo data. Other propagation properties of skin, backfat and muscle tissue obtained in a previous investigation were incorporated into the signal pre-processing to minimize parameter estimation artifacts. Spectr...

2012-01-01

462

Polarised foreground removal at low radio frequencies using rotation measure synthesis: Uncovering the signature of hydrogen reionisation  

CERN Document Server

Measurement of redshifted 21-cm emission from neutral hydrogen promises to be the most effective method for studying the reionisation history of hydrogen and, indirectly, the first galaxies. These studies will be limited not by raw sensitivity to the signal, but rather, by bright foreground radiation from Galactic and extragalactic radio sources and the Galactic continuum. In addition, leakage due to gain errors and non-ideal feeds conspire to further contaminate low-frequency radio obsevations. This leakage leads to a portion of the complex linear polarisation signal finding its way into Stokes I, and inhibits the detection of the non-polarised cosmological signal from the epoch of reionisation. In this work, we show that rotation measure synthesis can be used to recover the signature of cosmic hydrogen reionisation in the presence of contamination by polarised foregrounds. To achieve this, we apply the rotation measure ...

2010-01-01

463

Machine fault signature analysis by midpoint-based empirical mode decomposition  

Science.gov (United States)

The fault signature can be revealed by vibration analysis in machine fault detection and diagnosis. Empirical mode decomposition (EMD) is a self-adaptive method that can decompose a vibration signal into informative intrinsic mode functions (IMFs). This paper addresses the improvement of the weakness of the traditional EMD algorithm and presents a new midpoint-based EMD method for effective fault signature analysis of a rotating machine. In the proposed method, geometrical midpoints of successive extrema are employed to estimate the local mean of an analyzed signal. Signal decomposition is then self-adaptively performed to achieve IMFs through removal of the midpoint-based local means. The representative IMF containing fault information is selected for identifying the fault signature. The effectiveness of the proposed method was verified by means of simulation and an application to gear fault diagnosis. Results indicated ...

2011-01-01

464

MR findings of central nervous system involvement in acquired immunodeficiency syndrome patient : a report of two cases  

Energy Technology Data Exchange (ETDEWEB)

Central nervous system (CNS) manifestations in acquired immunodeficiency syndrome (AIDS) patients are an early and common feature. The spectrum of AIDS-related CNS diseases are encephalitis caused by the human immunodeficiency virus(HIV) itself, opportunistic infection, infarct and malignancy. We experienced two cases of CNS involvement in AIDS and they were serologically diagnosed as HIV encephalitis and CNS toxoplasmosis, respectively. In the case of the HIV encephalitis patient, brain MRI showed a non-enhancing lesion with high signal intensity on T2WI and low signal on T1WI and there was no mass effect on the right frontal lobe, periventricular white matter, splenium of the corpus callosum or bilateral basal ganglia. In the other case of CNS toxoplasmosis, MR showed multiple nodular and rim enhanced mass lesions in the right basal ganglia, thalamus and periventricular white matter, which were of low signal intensity on ...

1996-10-01

465

Isochron measurements of naturally irradiated K-feldspar grains  

International Nuclear Information System (INIS)

The equivalent doses of K-feldspar grains in a range of grain sizes from 90 to 250#mu#m diameter were measured using a single-aliquot regenerative-dose protocol for the infrared stimulated luminescence (IRSL) signals for two samples of desert sand. The equivalent doses for each sample were compared with that for the 125-150#mu#m grains of quartz from the same samples. The results suggested that the K-feldspar equivalent doses were underestimated because of anomalous fading. Measurements of the decay of the IRSL signals following laboratory irradiation for these two samples, and an additional one from a previously published isochron study, showed anomalous fading during the period of laboratory storage. The decay rate was about 3% per decade for all samples and was independent of the grain size used. Using plots of equivalent doses for K-feldspars as a function of their calculated internal dose rate, and the quartz equivalent dose as a function ...

2007-09-01

466

Fusion ldentification method for gas-liquid two-phase flow regime based on recurrence quantification characteristics  

International Nuclear Information System (INIS)

To increase further the accuracy of flow regime and considering the non-stationary characteristics of differential pressure fluctuation signals of gas-liquid two-phase flow, the flow regime identification method based on recurrence quantification analysis (RQA) and multi-sensor data fusion techniques is put forward. First of all, the recurrence quantification analysis method is used to extract the nonlinear feature parameters of the differential pressure fluctuation signals of gas-liquid two-phase flow, and data fusion of feature layer is conducted by QRA feature parameters of differential pressure signals of three pressure measure intervals, and composes the fusion feature vectors. The fused characteristic vector are input into the support vector machine for identify flow regime. The identification results for four typical flow regimes of air-water two-phase flow in horizontal pipe has shown that the reliability of the ...

2009-12-01

467

Functional MRI of the visual cortex and visual testing in patients with previous optic neuritis.  

DEFF Research Database (Denmark)

The volume of cortical activation as detected by functional magnetic resonance imaging (fMRI) in the visual cortex has previously been shown to be reduced following optic neuritis (ON). In order to understand the cause of this change, we studied the cortical activation, both the size of the activated area and the signal change following ON, and compared the results with results of neuroophthalmological testing. We studied nine patients with previous acute ON and 10 healthy persons served as controls using fMRI with visual stimulation. In addition to a reduced activated volume, patients showed a reduced blood oxygenation level dependent (BOLD) signal increase and a greater asymmetry in the visual cortex, compared with controls. The volume of visual cortical activation was significantly correlated to the result of the contrast sensitivity test. The BOLD signal increase correlated significantly to both the results of the ...

2002-01-01

468

Extremely low frequency electric and magnetic fields and cancer: A literature review  

Energy Technology Data Exchange (ETDEWEB)

Epidemiologic studies suggest a weak link between occupational or residential exposure to extremely low frequency electromagnetic fields and cancer, especially tumors of the central nervous and hematopoietic systems. This report discusses these studies with reference to basic research on ELF EMF bioeffects relevant to cancer-promoting mechanisms. Many of the studies suggest a possible interaction of ELF EMF with the immune system, endocrine system, or growth-regulatory signals and morphogenic movements that involve calcium flux through cell membranes. Many bioeffects have been reported only with certain specific combinations of frequency, amplitude, and orientation of the EMF signal with respect to the geomagnetic field. The possibility of signal-specific effects raises a complication in dosimetry for both epidemiologic and experimental studies since ELF EMF effects may not be directly related to field strength. The report ...

1989-12-01

469

Estimation of dose in irradiated chicken bone by ESR method  

Energy Technology Data Exchange (ETDEWEB)

The author studied the conditions needed to routinely estimate the radiation dose in chicken bone by repeated re-irradiation and measuring ESR signals. Chicken meat containing bone was {gamma}-irradiated at doses of up to 3kGy, accepted as the commercially used dose. The results show that points in sample preparation and ESR measurement are as follows: Both ends of bone are cut off and central part of compact bone is used for experiment. To obtain accurate ESR spectrum, marrow should be scraped out completely. Sample bone fragments of 1-2mm particle size and ca.100mg are recommended to obtain stable and maximum signal. In practice, by re-irradiating up to 5kGy and extrapolating data of the signal intensity to zero using linear regression analysis, radiation dose is estimated. For example, in one experiment, estimated doses of chicken bones initially irradiated at 3.0kGy, 1.0kGy, 0.50kGy and 0.25kGy were 3.4kGy, 1.3kGy, ...

1998-03-01

470

Eddy currents signal processing for steam generator inspection in PWR nuclear power plants; Traitement des signaux de courants de Foucault pour le controle des tubes de generateurs de vapeur dans les centrales nucleaires REP  

Energy Technology Data Exchange (ETDEWEB)

Steam generator tubes in nuclear power plants are periodically checked by means of eddy current probes. The output of a probe is composed of three types of signals: known events (rolling zone, support plates, U-bend part), noise (mainly metallurgical noise) and possible flaws. The latter are random transients, both in arrival time and in shape: they have to be detected and then estimated, before to be fed to the high level stages of a diagnostics system. The objective of the study presented is to develop a semi-automatic system, which could manage and process more than 1 M-bytes of data per tube and provide an operator with reliable diagnostics proposals within a few minutes. This can be achieved only by cooperation of several digital signal processing techniques: detection, segmentation, estimation, noise subtraction, adaptive filtering, modelization, pattern recognition. The paper describes some of these items.

1991-07-01

471

Eddy currents signal processing for steam generator inspection in PWR nuclear power plants. Traitement des signaux courants de Foucault pour le controle des tubes de generateurs de vapeur dans les centrales nucleaires REP  

Energy Technology Data Exchange (ETDEWEB)

Steam generator tubes in nuclear power plants are periodically checked by means of eddy current probes. The output of a probe is composed of three types of signals: known events (rolling zone, support plates, U-bend part), noise (mainly metallurgical noise) and possible flaws. The latter are random transients, both in arrival time and in shape: they have to be detected and then estimated, before to be fed to the high level stages of a diagnostic system. The objective of the study presented is to develop a semi-automatic system, which could manage and process more than 1 M-bytes of data per tube and provide an operator with reliable diagnostics proposals within a few minutes. This can be achieved only by cooperation of several digital signal processing techniques: detection, segmentation, estimation, noise subtraction, adaptive filtering, modelization, pattern recognition. The paper describes some of these items.

1992-01-01

472

Detecting exposure to environmental organic toxins in individual cells: towards development of a micro-fabricated device  

Energy Technology Data Exchange (ETDEWEB)

A new method is being developed to quickly screen for the human exposure potential to polycyclic aromatic hydrocarbons (PAHs) and organochlorines (OCs). The development involves two key elements: identifying suitable signals that represent intracellular changes that are specific to PAH and OC exposure, and constructing a device to guide the biological cell growth so that signals from individual cells are consistent and reproducible. We are completing the identification of suitable signals by using synchrotron radiation-based (SR) Fourier-transform infrared (FTIR) spectromicroscopy in the mid-infrared region (4000-400 cm-1). Distinct changes have been observed in the IR spectra after treatment of human cells in culture medium with PAHs and OCs. The potential use of this method for detecting exposure to PAHs and OCs has been tested and compared to a reverse transcription polymerase chain reaction (RT-PCR) assay that ...

1999-01-10

473

Creating an EPICS Based Test Stand Development System for a BPM Digitizer of the Linac Coherent Light Source  

Energy Technology Data Exchange (ETDEWEB)

The Linac Coherent Light Source (LCLS) is required to deliver a high quality electron beam for producing coherent X-rays. As a result, high resolution beam position monitoring is required. The Beam Position Monitor (BPM) digitizer acquires analog signals from the beam line and digitizes them to obtain beam position data. Although Matlab is currently being used to test the BPM digitizer?s functions and capability, the Controls Department at SLAC prefers to use Experimental Physics and Industrial Control Systems (EPICS). This paper discusses the transition of providing similar as well as enhanced functionalities, than those offered by Matlab, to test the digitizer. Altogether, the improved test stand development system can perform mathematical and statistical calculations with the waveform signals acquired from the digitizer and compute the fast Fourier transform (FFT) of the signals. Finally, logging of meaningful data into ...

2011-06-22

474

An availability of brain magnetic resonance imaging (MRI) in the early diagnosis of latent hepatic encephalopathy  

Energy Technology Data Exchange (ETDEWEB)

Brain MRI was carried out in patients with chronic liver diseases. No abnormal findings were recognized in patients with chronic viral hepatitis, while 59.2% of cirrhotics showed a symmetrically strong signal in basal ganglia on T1 weighted image in MRI. This finding significantly related with lowered Fischer`s ratio of serum amino acid, increased levels of serum phenylalanine, tyrosine and hyaluronic acid, prolonged prothrombin time and decreased platelet counts in the peripheral blood. Overt hepatic encephalopathy was observed in 6 of 34 patients with the strong signal in MRI during follow-up period, while none of patients without that finding developed hepatic encephalopathy. These results have indicated that the strong signal in basal ganglia on MRI appears in cirrhotic patients with severe liver dysfunction, and it is an useful index in the early diagnosis of latent hepatic encephalopathy. An improvement of this MRI ...

1996-03-01

475

Adaptive and mobile ground sensor array.  

Energy Technology Data Exchange (ETDEWEB)

The goal of this LDRD was to demonstrate the use of robotic vehicles for deploying and autonomously reconfiguring seismic and acoustic sensor arrays with high (centimeter) accuracy to obtain enhancement of our capability to locate and characterize remote targets. The capability to accurately place sensors and then retrieve and reconfigure them allows sensors to be placed in phased arrays in an initial monitoring configuration and then to be reconfigured in an array tuned to the specific frequencies and directions of the selected target. This report reviews the findings and accomplishments achieved during this three-year project. This project successfully demonstrated autonomous deployment and retrieval of a payload package with an accuracy of a few centimeters using differential global positioning system (GPS) signals. It developed an autonomous, multisensor, temporally aligned, radio-frequency communication and signal processing capability, ...

2003-12-01

476

A Global Framework for Monitoring Phenological Responses to Climate Change  

Energy Technology Data Exchange (ETDEWEB)

Remote sensing of vegetation phenology is an important method with which to monitor terrestrial responses to climate change, but most approaches include signals from multiple forcings, such as mixed phenological signals from multiple biomes, urbanization, political changes, shifts in agricultural practices, and disturbances. Consequently, it is difficult to extract a clear signal from the usually assumed forcing: climate change. Here, using global 8 km 1982 to 1999 Normalized Difference Vegetation Index (NDVI) data and an eight-element monthly climatology, we identified pixels whose wavelet power spectrum was consistently dominated by annual cycles and then created phenologically and climatically self-similar clusters, which we term phenoregions. We then ranked and screened each phenoregion as a function of landcover homogeneity and consistency, evidence of human impacts, and political diversity. Remaining phenoregions ...

2005-02-01

477

A Bragg curve counter with an active cathode to improve the energy threshold in fragment measurements  

Energy Technology Data Exchange (ETDEWEB)

We have developed a Bragg curve counter (BCC) equipped with an active cathode to extend the energy acceptance to lower energies than for a conventional BCC to measure differential cross-sections of fragment production reactions induced by tens of MeV protons. The signal from the active cathode providing the timing signal of fragment incidence and the time difference signal between the cathode and anode gives information on the fragment range in the BCC on the basis of electron drift time. Utilization of the range information made possible identification of fragments less than 0.5 MeV/u that is lower than the identification threshold of a conventional BCC technique. After investigations on fundamental properties of a newly constructed BCC using heavy ion beams and alpha-particles, this method was applied successfully to a fragment production measurement for 70 MeV proton-induced reactions on carbon. With this technique, the ...

2008-05-01

478

3-D modelling the electric field due to ocean tidal flow and comparison with observations  

DEFF Research Database (Denmark)

The tidal motion of the ocean water through the ambient magnetic field, generates secondary electric field. This motionally induced electric field can be detected in the sea or inland and has a potential for electrical soundings of the Earth. A first goal of the paper is to gain an understanding of the global distribution of the electric signal due to tidal ocean flow. We simulate the electric signals for two tidal constituents - lunar semidiurnal (M2) and diurnal (O1) tides. We assume a realistic Earth's conductivity model with a surface thin shell and 1-D mantle underneath. Simulations demonstrate that in some coastal regions the amplitudes of the electric field can reach 100 mV/km and 10 mV/km for M2 and O1 tides respectively. The changes of lithosphere resistance produce detectable changes in the tidal electric signals. We show that our predictions are in a good agreement with observations.

2006-01-01

479

Modulation of neuronal differentiation by CD40 isoforms  

International Nuclear Information System (INIS)

Neuron differentiation is a complex process involving various cell-cell interactions, and multiple signaling pathways. We showed previously that CD40 is expressed and functional on mouse and human neurons. In neurons, ligation of CD40 protects against serum withdrawal-induced injury and plays a role in survival and differentiation. CD40 deficient mice display neuron dysfunction, aberrant neuron morphologic changes, and associated gross brain abnormalities. Previous studies by Tone and colleagues suggested that five isoforms of CD40 exist with two predominant isoforms expressed in humans: signal-transducible CD40 type I and a C-terminal truncated, non-signal-transducible CD40 type II. We hypothesized that differential expression of CD40 isoform type I and type II in neurons may modulate neuron differentiation. Results show that adult wild-type, and CD40"-"/"- deficient mice predominantly express CD40 type I and II isoforms. ...

2008-05-02

480

Status report about the revision of an IEC standard for personal dose equivalent meters for H{sub p}(10) and H{sub p}(0,07); Statusbericht ueber die Neufassung einer IEC-Norm fuer H{sub p}(10)- und H{sub p}(0,07)-Personendosimeter  

Energy Technology Data Exchange (ETDEWEB)

A working group (SC 45B/WG B8) exists within the international electrochemical commission (IEC) which is working on the combination and revision of the IEC standards 61283, 61323, 61344, 61525 and 61526. All these standards concern direct reading, electronic, personal dose equivalent meters for the quantities H{sub p}(10) and H{sub p}(0,07); they are different with regard to the kind of radiation (photons, and/or beta rays and/or neutrons). The new standard with the number 61526 shall cover the following topics: 1. Combination of all the mentioned standards; 2. Maintenance of the essential requirements of the former standards; 3. Inclusion of the determination of the uncertainty of measurement for the measured dose equivalent value according to the ''Guide to the Expression of Uncertainty in Measurement''; 4. Consideration of all the relevant ISO-standards for reference radiation fields for photon, beta and neutron radiations; 5. Consideration of ...

2001-07-01

481

Wnt/b-catenin signal pathway stabilizes APP intracellular domain (AICD) and promotes its transcriptional activity  

British Library Electronic Table of Contents (United Kingdom)

Amyloid precursor protein (APP), a key protein in pathogenesis of Alzheimer's disease (AD), is a type I transmembrane protein which can be cleaved by b- and g-secretase to release the amyloidogenic b-amyloid peptides (Ab) and the APP intracellular domain (AICD). While Ab has been widely believed to initiate pathogenic cascades culminating AD, the physiological functions and regulations of AICD remain elusive. In present study, endogenous AICD was demonstrated to be increased by canonical Wnt signal. Instead of due to g-secretase activity, enhanced AICD expression was found due to the increased protein stability by Wnt/b-catenin. b-Catenin was demonstrated to be an associating partner of AICD, capable of promoting AICD mediated transcriptional activity. Investigation by AICD mutants proved ...

2011-01-01

482

Video and seismic observations of Strombolian eruptions at Erebus volcano, Antarctica  

British Library Electronic Table of Contents (United Kingdom)

Between 1986 and 1990 the eruptive activity of Erebus volcano was monitored by a video camera with on-screen time code and recorded on video tape. Corresponding seismic and acoustic signals were recorded from a network of 6 geophones and 2 infrasonic microphones. Two hundred Strombolian explosions and three lava flows which were erupted from 7 vents were captured on video. In December 1986 the Strombolian eruptions ejected bombs and ash. In November 1987 large bubble-bursting Strombolian eruptions were observed. The bubbles burst when the bubble walls thinned to ?20?cm. Explosions with bomb flight-times up to 14.5?s were accompanied by seismic signals with our local size estimate, ?unified magnitudes?? (mu), up to 2.3. Explosions in pools of lava formed by flows in the Inner Crater were co...

2008-01-01

483

Use of lanthanide shift reagents together with silver trifluoroacetate for quantitative analysis of mixtures of aromatic hydrocarbons  

Energy Technology Data Exchange (ETDEWEB)

The shifts induced by equimolar mixture of typical lanthanide shift reagent such as 2,2-dimethyl-6,6,7,7,8,8,8-heptafluoro-3,5-octadionato europium with silver trifluoroacetate in /sup 1/H NMR spectra of aromatic hydrocarbons have been used for analytical purposes; the NMR determination of m- and p-xylenes in mixtures has been chosen as an example. The use has been made of the difference between induced shifts of methyl group signals in the /sup 1/H NMR spectra of m- and p-xylenes. The magnitude of induced shifts of methyl groups signal in m-xylene is always larger than that of p-isomer, irrespective of contents of m- and p-xylenes in mixture.

1980-01-01

484

The spatial distribution of argon clusters in gas jet  

International Nuclear Information System (INIS)

The spatial distribution of argon clusters in gas jet is tested using the Rayleigh scattering method. A pulsed laser is used to acquire the whole evolution of the cluster inside one event. The measured results at a fixed axial position show that the argon clusters grow in less than one millisecond after the nozzle is opened and the cluster size keeps constant during the whole open period of 20 ms. Further results show that the scattering signal along the radial direction is almost Gaussian-distributed and the full width half maximum (FWHM) increases almost linearly when the distance from nozzle increases. The scattering signal along the axial direction is Landau-distributed and the area near the nozzle is most effective for laser cluster interaction. (authors)

2010-02-01

485

The development of technology on chicken yard design and its environment control  

Energy Technology Data Exchange (ETDEWEB)

The objective of this study is development of technology on chicken yard design and its environment control. For this objective, the micro processor interface techniques and related programming techniques have been surveyed, and the chicken yard environment monitoring system has been developed that equipped with micro computer and signal measurement module. Software has also been developed that operated the system and analyzes measured data. By using micro computer and signal input/output module, the system can have various functions, such as monitoring, alarm, and data analysis function. Three dimensional graphic modeling of a chicken yard is performed using graphic package in this study. Application of three dimensional modeling technique make it easy to design chicken yard. 9 figs. (Author)

1996-04-01

486

Search for Z' ---> e+ e- using dielectron mass and angular distribution  

Energy Technology Data Exchange (ETDEWEB)

The authors search Z{prime} bosons in dielectron events produced in p{bar p} collisions at {radical}s = 1.96 TeV, using a 0.45 fb{sup -1} dataset accumulated with the CDF II detector at the Fermilab Tevatron. To identify the Z{prime} {yields} e{sup +}e{sup -} signal, both the dielectron invariant mass distribution and the angular distribution of the electron pair are used. No evidence of a signal is found, and 95% confidence level lower limits are set on the Z{prime} mass for several models. Limits are also placed on the mass and gauge coupling of a generic Z{prime}, as well as on the contact interaction mass scales for different helicity structure scenarios.

2006-02-01

487

Point-contact Andreev reflection spectroscopy of heavy-fermion-metal/superconductor junctions  

Energy Technology Data Exchange (ETDEWEB)

Our previous point-contact Andreev reflection studies of the heavy-fermion superconductor CeCoIn{sub 5} using Au tips have shown two clear features: reduced Andreev signal and asymmetric background conductance. To explore their physical origins, we have extended our measurements to point-contact junctions between single crystalline heavy-fermion metals and superconducting Nb tips. Differential conductance spectra are taken on junctions with three heavy-fermion metals, CeCoIn{sub 5}, CeRhIn{sub 5}, and YbAl{sub 3}, each with different electron mass. In contrast with Au/CeCoIn{sub 5} junctions, Andreev signal is not reduced and no dependence on effective mass is observed. A possible explanation based on a two-fluid picture for heavy fermions is proposed.

2008-04-01

488

Point -contact Andreev reflection spectroscopy of heavy-fermion-metal/superconductor junctions  

Energy Technology Data Exchange (ETDEWEB)

Our previous point-contact Andreev reflection studies of the heavy-fermion superconductor CeCoIn{sub 5} using Au tips have shown two clear features: reduced Andreev signal and asymmetric background conductance. To explore their physical origins, we have extended our measurements to point-contact junctions between single crystalline heavy-fermion metals and superconducting Nb tips. Differential conductance spectra are taken on junctions with three heavy-fermion metals, CeCoIn{sub 5}, CeRhIn{sub 5}, and YbAl{sub 3}, each with different electron mass. In contrast with Au/CeCoIn{sub 5} junctions, Andreev signal is not reduced and no dependence on effective mass is observed. A possible explanation based on a two-fluid picture for heavy fermions is proposed.

2008-01-01

489

Optimal conditions for stability of photoemission and freeze drying of two luminescent bacteria for use in a biosensor  

British Library Electronic Table of Contents (United Kingdom)

Abstract Bioluminescent bacteria have been used for many years for biotoxicological analysis. One of the main concerns with this microorganism is the low experimental repeatability when subjected to external factors. The aim of the present study was to obtain accurate, sensitive, and repeatable measurements with stable signals (during the detection and over days) for application in a water-analysis device for the detection of pollutants. Growth conditions were tested and optimized. An optimal freeze-drying procedure for the constitutive bioluminescent bacteria Vibrio fischeri and Photobacterium phosphoreum was developed. The luminescence stability after rehydration was also investigated. Freeze drying was found to be a critical process in survival and signal stability of luminescent bacter...

2011-01-01

490

Market-based pricing and demand-side participation in the electricity pool of England and Wales  

Energy Technology Data Exchange (ETDEWEB)

This paper focuses upon the workings of the electricity pool of England and Wales. Created as a generators` pool, with the twin objectives of preserving order-of-merit dispatch and setting marginal-cost pricing signals, it is now evident that the system may not provide an efficient market-clearing mechanism from the consumers` perspective. Thus, over the five years since its inception, there have been repeated calls to incorporate more explicitly demand-side pricing signals into the process. A number of official reviews and various consultants have looked at the issue and there have been trial periods of active demand-side bidding. This paper reviews that experience to date.

1996-03-01

491

Mapping Equivalence for Symbolic Sequences: Theory and Applications  

CERN Document Server

Processing of symbolic sequences represented by mapping of symbolic data into numerical signals is commonly used in various applications. It is a particularly popular approach in genomic and proteomic sequence analysis. Numerous mappings of symbolic sequences have been proposed for various applications. It is unclear however whether the processing of symbolic data provides an artifact of the numerical mapping or is an inherent property of the symbolic data. This issue has been long ignored in the engineering and scientific literature. It is possible that many of the results obtained in symbolic signal processing could be a byproduct of the mapping and might not shed any light on the underlying properties embedded in the data. Moreover, in many applications, conflicting conclusions may arise due to the choice of the mapping used for numerical representation of symbolic data. In this paper, we present a novel framework for the analysis of the ...

2009-01-01

492

Initial airborne CO{sub 2} DIAL measurements: Discussion of results and data analysis considerations  

Energy Technology Data Exchange (ETDEWEB)

A detailed discussion of airborne CO{sub 2}, DIAL measurements obtained from the first joint N-ABLE field campaign at INEL is presented. System performance characteristics, including return signal strength, averaging statistics, and temporal correlation as well as multi-line DIAL spectral data are discussed. In particular, we review data acquisition and analysis strategies pertinent to chemical detection from a moving platform, such as range determination and correction, and return signal processing (waveform vs. box-car integration, baseline correction). We also report observed effects and variations due to near-field light scattering, pointing and tracking stability, and stack-release plume dynamics.

1997-07-01

493

Endogenous expression of Hras(G12V) induces developmental defects and neoplasms with copy number imbalances of the oncogene.  

Science.gov (United States)

We developed mice with germline endogenous expression of oncogenic Hras to study effects on development and mechanisms of tumor initiation. They had high perinatal mortality, abnormal cranial dimensions, defective dental ameloblasts, and nasal septal deviation, consistent with some of the features of human Costello syndrome. These mice developed papillomas and angiosarcomas, which were associated with Hras(G12V) allelic imbalance and augmented Hras signaling. Endogenous expression of Hras(G12V) was also associated with a higher mutation rate in vivo. Tumor initiation by Hras(G12V) likely requires augmentation of signal output, which in papillomas and angiosarcomas is achieved via increased Hras-gene copy number, which may be favored by a higher mutation frequency in cells expressing the oncoprotein. PMID:19416908

2009-04-29

494

Detection of irradiated chicken by ESR spectroscopy of bone  

Energy Technology Data Exchange (ETDEWEB)

Ionizing radiation has been used to treat poultry to remove harmful microorganisms, mainly Salmonella, which contaminates chicken, goose and other fresh and frozen poultry. This microorganism is sensitive to low dose radiation. Thus, irradiating these foods with doses between 1 to 7 kGy results in a large reduction of bacteria. Since it is necessary to determine whether irradiation has occurred and to what extend, this work studied the signal produced by ionizing radiation within the hard crystalline matrix of chicken`s bone to establish a control method. Chicken`s drumsticks were irradiated and bones separated from flesh were lyophilized and milled. ESR spectrum was then obtained. The ESR signal increased linearly with dose over the range 0.25 to 8.0 kGy. Free radicals evaluated during 30 days after irradiation showed stable in this period. (Author).

1995-10-01

495

Correlation of MRI and histomorphological findings in bone marrow oedema syndrome of the hip  

Energy Technology Data Exchange (ETDEWEB)

In 15 patients (16 hip joints) we found the clinical and radiological signs of BMOS. On T1-weighted MRI images areas of low signal intensity could be observed in the head, neck and the intertrochanteric region of the femur in various extensions. These areas showed a significant increase in signal intensity on the T2-weighted images. Because pain was resistant to conservative therapy all these patients were treated by core decompression of the femoral head in a prospective study. Bone cores were evaluated histologically using undecalcified sections and quantitative microradiography. The existence of intramedullary oedema in exactly the regions exhibiting the MRI pattern of bone marrow oedema was verified histologically; however, bone and marrow changes similar to those of early avascular necrosis (AVN) were also visible. (orig.)

1993-10-01

496

Cooling device for impurity removal device in thermonuclear devices  

International Nuclear Information System (INIS)

Purpose: To prevent structure material meltdown upon rupture of cooling pipeways in a impurity remover by preventing the coolants from flowing into the vacuum vessel while continuing the supply of coolants to other portions to be cooled. Constitution: Dual cooling pipeway systems are disposed to the neutralizing plates of the impurity remover. A rupture detector (pressure gage) is mounted to each of the cooling pipeways and flow rate control valves to be opened and closed by the signal from the detector are disposed to the upstream and downstream of the cooling pipeway. In this constitution if the cooling pipes should be ruptured, the coolant supply is stopped to the ruptured system in which the flow rate valve is closed by the signal from the rupture detector. However, since the coolant is kept to be supplied to the other system of the cooling pipeways, meltdown of the neutralizing plates can be prevented. (Kamimura, M.).

1983-08-26

497

Chronic sympathetic activation promotes downregulation of ?-adrenoceptor-mediated effects in the guinea pig heart independently of structural remodeling and systolic dysfunction  

British Library Electronic Table of Contents (United Kingdom)

It is uncertain if downregulation of ?-adrenoceptor signaling pathway is promoted by an enhanced adrenergic tone at an early stage of cardiac disease, or it develops secondary to detrimental local myocardial changes in advanced heart failure. We examined the integrity of ?-adrenoceptor signaling pathway upon chronic infusion of isoproterenol, a ?-adrenoceptor agonist, at a dose producing no structural left ventricular (LV) remodeling and systolic dysfunction. Subcutaneous isoproterenol infusion (400??g?kg?1?h?1 over 16?days) to guinea pigs using osmotic minipumps produced no change in cardiac weights, LV internal dimensions, myocyte cross-sectional area, extent of interstitial fibrosis, and basal contractile function. Isolated, perfused heart preparations from isoproterenol-treated guinea ...

2011-01-01

498

Cell fate regulation by coupling mechanical cycles to biochemical signaling pathways  

British Library Electronic Table of Contents (United Kingdom)

Many aspects of cellular motility and mechanics are cyclic in nature such as the extension and retraction of lamellipodia or filopodia. Inherent to the cycles of extension and retraction that test the environment is the production of mechano-chemical signals that can alter long-term cell behavior, transcription patterns, and cell fate. We are just starting to define such cycles in several aspects of cell motility, including periodic contractions, integrin cycles of binding and release as well as the normal oscillations in motile activity. Cycles of local cell contraction and release are directly coupled to cycles of stressing and releasing extracellular contacts (matrix or cells) as well as cytoplasmic mechanotransducers. Stretching can alter external physical properties or sites exposed b...

2009-01-01