Choosing a future for epidemiology: I. Eras and paradigms.
UK PubMed Central (United Kingdom)
To inform choices about the future of epidemiology, the present condition of epidemiology is examined, in terms of its evolution through three eras, each demarcated by its own paradigm: (1) the era...Full Text Available
1996-05-01
Channel Rehabilitation: Processes, Design, and ...
... time. The Paleozoic Era ended only 248 million years ago, the Mesozoic Era ended only 65 million years ago, and so on. ...
1999-07-01
Safety and immunogenicity of a vaccine bait containing ERA strain of attenuated rabies virus.
UK PubMed Central (United Kingdom)
Ninety percent of foxes fed commercial ERA vaccine in a specially designed bait developed rabies serum neutralizing antibodies. The vaccine bait did not cause clinical signs of rabies when consumed...Full Text Available
1987-10-01
RefLexiones sobre la inmensidad del universo.La materia vista desde la Grecia antigua hasta la era m
RefLexiones sobre la inmensidad del universo.La materia vista desde la Grecia antigua hasta la era m
2009-01-01
Safety and immunogenicity of ERA strain of rabies virus propagated in a BHK-21 cell line.
UK PubMed Central (United Kingdom)
The ERA strain of rabies virus was propagated in a baby hamster kidney cell line (BHK-21/C13). The viral titer was 10(1.8) tissue culture infective doses (TCID) higher than that of commercial ERA vaccine....Full Text Available
1989-10-01
Netware-Specific Network Security.
This paper focuses on practical and cost-effective NetWare-specific approaches to information systems and computer security. A series of real world experiences is presented that illustrate fundamental information systems and security concepts. A NetWare network is a client-server network which uses a file server to share files while client workstations access the file server via some network typology (usually ethernet or token ring). Passwords are used to authenticate users; thus, password protection is a cornerstone of network security. Passwords can be encrypted, but this feature can be disabled. The bindery, which stores information about users, groups, and printers, is critical to the network and must be backed up. Trade secrets can be hidden from users by restructuring menus. Login scripts should be protected and not used for security purposes. Guest account access should be restricted or removed. Finally, the "security.exe" program can ...
1994-12-01
TIGER in Antarctica - Q&A - Misc. Antarctic Topics - NASA
Jan 5, 2004 ... Even if dinosaurs were cold-blooded, in the Mesozoic Era (when dinosaurs roamed the Earth), Antarctica was warm enough to have them. ...
Sun rises on station era - Johnson Space Center - NASA
Dec 4, 1998 ... throwing a single switch to as complex as the Spartan deploy and retrieve. ...... The camera, called the Acousto-Optic ...
ISS020-E-9861 - The Gateway to Astronaut Photography of Earth
The portion of the Waterpocket Fold illustrated in this image includes layered rocks formed during the Mesozoic Era (~ 250 65 million years ago) the oldest ...
Experimental medicine 1000 years ago
UK PubMed Central (United Kingdom)
Little is known about the state of experimentation in the field of medicine during the Medieval Islamic era. With few exceptions, most of the contemporary sources on history of medicine propagate the...Full Text Available
2011-05-01
Evaluating Phylogenetic Congruence in the Post-Genomic Era
UK PubMed Central (United Kingdom)
Congruence is a broadly applied notion in evolutionary biology used to justify multigene phylogeny or phylogenomics, as well as in studies of coevolution, lateral gene transfer, and as evidence for...Full Text Available
2011-01-01
Denali National Park and Preserve Geologic Resources Inventory Report
... the Mississippian Antler orogeny (Condie and Sloan 1998). Mesozoic Era (251 to 65.5 million years ago) The ... half of the Paleozoic and beginning of the Mesozo...
... with the loosening of Bush-era restrictions on stem cell research, a move that was widely hailed by the ... The first two explore the contentious debate over stem cell research. Using a series of intervie...
Chemical and physical change of packaging materials for food by gamma-ray irradiation
International Nuclear Information System (INIS)
Recently, foods are often exposed to radiation under packed states with various wrapping materials. In this study, the effects of #gamma#-ray radiation were investigated on the additives in wrapping materials on the market. 10 - 50 kGy #gamma# radiation was irradiated to samples under sealed condition in a glass-ware. Polyethylene bag and wrapping film, polypropylene wrapping film, cup and sheet, and polystyrene cup were used as samples. And the additives in these materials were analyzed by GC/MS to evaluate the radiation effects on them. The irradiation was found to induce rapid degradation of antioxidants, especially, Irgafos 168. Some fatty acid amides used as a lubricant and a plasticizer, DBP were also reduced, but not aliphatic hydrocarbons. However, all polystyrene products used in this study included no additives. The contents of styrene dimer and trimer in those wrapping materials were not changed by #gamma#-irradiation. (M.N.)
1999-02-01
Transition of rotating Bianchi type-IX cosmological model into an inflationary era
Energy Technology Data Exchange (ETDEWEB)
A Bianchi type-IX cosmological model has been found as a solution of Einstien's vacuum field equations with a cosmological constant. The solution represents a rotating generalziation fo the de Sitter universe. This universe shows a transition to exponential expansion and the vorticity begins to decay exponentially at the grand-unified-theory time. The point of time for this transition is independent of the magnitude of the vorticity. During the Guth inflationary era the vorticity decays by a factor of the order 10 US.
1986-02-15
Transition of rotating Bianchi type-IX cosmological model into an inflationary era
International Nuclear Information System (INIS)
A Bianchi type-IX cosmological model has been found as a solution of Einstien's vacuum field equations with a cosmological constant. The solution represents a rotating generalziation fo the de Sitter universe. This universe shows a transition to exponential expansion and the vorticity begins to decay exponentially at the grand-unified-theory time. The point of time for this transition is independent of the magnitude of the vorticity. During the Guth inflationary era the vorticity decays by a factor of the order 10"-"1"4"2.
Periodicity of the Phanerozoic magmatism in Mongolia from potassium-argon data
International Nuclear Information System (INIS)
An attempt was made to set the main potassium-argon (PA) boundaries in magmatism development in the territory of Mongolia. Results were correlated with the known concepts about periodicity of magmatism. Possibility of using PA analysis for separation of magmatic rocks was evaluated. Reliable correlation of significant PA boundaries of magmatism with geological periodization of tectonomagmatic events in Mesozoic era and Late Paleozoic era was established.
1989-01-01
UK PubMed Central (United Kingdom)
Locomotive drivers in the steam engine era were exposed to asbestos during their vocational training for two years while training in workshops. Later in their career they had exposure to coal and diesel...Full Text Available
1994-05-01
Origins, evolution, and phenotypic impact of new genes
UK PubMed Central (United Kingdom)
Ever since the pre-molecular era, the birth of new genes with novel functions has been considered to be a major contributor to adaptive evolutionary innovation. Here, I review the origin and evolution...Full Text Available
2010-10-01
NASA SBIR & STTR 2010 ... - NASA's SBIR & STTR Programs
The Heliophysics roadmap: "The Solar and Space Physics of a New Era: ..... Improved materials and manufacturing processes to produce Iridium/Rhenium apogee class ... In addition to batteries, other advanced energy storage/load leveling ...
Mesozoic Era of relativistic heavy ion physics and beyond.
In order to understand how matter 15 billion years ago in the form of quarks, gluons and leptons at a temperature of 2 (times) 10(sup 12) (degrees)K evolved to become today's Universe, the goal of relativistic and ultra-relativistic heavy ion physics is t...
1994-01-01
Information Sharing in the Era of WikiLeaks: Balancing Security and Collaboration.
As the IC Information Sharing Executive (IC ISE), my main focus today concerns classified information--and, in particular, information that is derived from intelligence sources and methods, or information that is reflected in the analytic judgments and as...
2011-01-01
Genetic susceptibility to systemic lupus erythematosus in the genomic era
UK PubMed Central (United Kingdom)
Our understanding of the genetic basis of systemic lupus erythematosus (SLE) has been rapidly advanced using large-scale, case–control, candidate gene studies as well as genome-wide...Full Text Available
2010-12-01
Expedition crew rotation highlights upcoming shuttle mission
Feb 23, 2001 ... Florida, as an F-16 weapons separation engineer with .... new era of space-based research aboard the International Space. Station. ..... the Web at: http://www. aiaa.org/calen- dar/index.hfm?cal=1&cfp=1 ...
Comparison and co-relation of invasive and noninvasive methods of ejection fraction measurement.
UK PubMed Central (United Kingdom)
BACKGROUND: Accurate estimation of left ventricular ejection fraction (LVEF) has assumed great significance in the era of automatic implantable cardioverter defibrillators (AICDs), and a low EF may...Full Text Available
2007-11-01
UK PubMed Central (United Kingdom)
In this era of complete genomes, our knowledge of neuroanatomical circuitry remains surprisingly sparse. Such knowledge is critical, however, for both basic and clinical research into brain function....Full Text Available
2009-03-01
Neutron star evolution with internal heating
Energy Technology Data Exchange (ETDEWEB)
The thermal evolution predicted by current models of the superfluid-crust interaction is noted to differ substantially from the thermal evolution predicted by models without internal heating as well as previous models of heating. Heating rates approaching the maximum predicted by current models enhance the photon luminosity of the star in the neutrino cooling era, and dramatically alter the thermal evolution in the photon cooling era. Standard cooling models are consistent with current pulsar temperature estimates and upper limits, except those for the Vela pulsar, which are lower than predicted. 77 refs.
1989-11-01
Engines of Creation 2.0: The Coming Era of Nanotechnology - Updated and Expanded
Engines of Creation 2.0: The Coming Era of Nanotechnology -- Updated and Expanded, is an ebook-only version available for free to readers exclusively through WOWIO. In addition to an updated "look and feel" for the ebook, Engines of Creation 2.0 has been expanded to include the first known lecture on nanotechnology by physicist Richard Feynman, the landmark open letter debate between Dr. Drexler and the late nanotech pioneer and Nobel laureate Dr. Richard Smalley, analysis of the debate by Ray Kurzweil, and a number of new additions by Dr. Drexler, including his advice to aspiring nanotechnologists.
2010-11-25
Energy Technology Data Exchange (ETDEWEB)
Effect of the coverage of shot peening, the surface roughness and shot shape, etc. on the stress corrosion cracking (SCC) of Alloy 800 in alkaline solutions was studied. Alloy 800 specimens were cracked in boiling alkaline solutions at the potntial range of {minus} 100 to 0mV in the boiling 50%NaOH+0.3%SiO {sub 2} solution. U bend specimens were tested under the polarized condition at the controlled potential to 0mV, showing that shot peened specimens cracked more easily. Tests of specimens with the same hardness showed that specimens hardened by cold working showed the higher susceptivity than that of surface hardened specimens. In these connections, U bend specimens of higher shot peened coverage were cracked at conditions of 593K and 10%NaOH solution. O-ring specimens of smaller stress level did not show any cracks independent of surface treatments. 8 refs., 9 figs., 5 tabs.
1990-03-15
Computer Network Security: Best Practices for Alberta School Jurisdictions.
This paper provides a snapshot of the computer network security industry and addresses specific issues related to network security in public education. The following topics are covered: (1) security policy, including reasons for establishing a policy, risk assessment, areas to consider, audit tools; (2) workstations, including physical security, protecting workstation components, and computer viruses; (3) the local network, including the OSI (Open Systems Interconnection) reference model, protocols, network segmentation, network management, network sniffing, and data encryption; (4) servers, including UNIX and other server operating systems; (5) remote access, including technologies, remote access servers, protocols, and authentication/authorization; (6) crackers and hackers, including threats and hacking tools/techniques; (7) Internet firewalls, including functions, issues and problems, types, rules, logs, firewall accessories, buying a firewall, and firewall administration; and (8) ...
1999-02-01
UK PubMed Central (United Kingdom)
The consistently observed inverse relationship of allergic conditions with glioma risk and our previous demonstration that IgE levels also were lower in glioma patients than controls suggest...Full Text Available
2009-08-01
Convergenomics Strategic Innovation in the Convergence Era
Convergenomics is about the megatrends that are shaping how people behave and organizations work. In this insightful analysis, Sang Lee and David Olson describe how globalization, digitization, changing demographics, changing industry mix, deregulation and privatization, commoditization of processes, new value chains, emerging new economies, deteriorating environment, and cultural conflicts have led to what they define as a convergence revolution.Lee and Olson discuss this convergence revolution from the perspectives of technology, industry, knowledge, open-source networking and bio-artificial
2010-01-01
Tabulated data are presented from air monitoring studies in the vicinity of the Chalk Point fossil-fuel power plant located in a coastal region of Maryland. (ERA citation 02:057363)
1977-01-01
Energy Technology Data Exchange (ETDEWEB)
A new era for the field of Galactic structure is about to be opened with the advent of wide-area digital sky surveys. In this article, the author reviews the status and prospects for research for 3 new ground-based surveys: the Sloan Digital Sky Survey (SDSS), the Deep Near-Infrared Survey of the Southern Sky (DENIS) and the Two Micron AU Sky Survey (2MASS). These surveys will permit detailed studies of Galactic structure and stellar populations in the Galaxy with unprecedented detail. Extracting the information, however, will be challenging.
1994-11-01
Energy Technology Data Exchange (ETDEWEB)
This is an account of the initial struggles and subsequently successful career of a young woman growing up in prewar Australia with the overriding desire to become a physicist despite various problems and prejudices. The book provides first-hand accounts of wartime radar research and development in Australia; the immediately post-war era in nuclear physics at the Cavendish Laboratory, Cambridge; and work in the Nuclear Physics Division at AERE Harwell in the period from the 1950s onwards. (UK).
1991-01-01
UK PubMed Central (United Kingdom)
The great medieval settlement of Angkor in Cambodia [9th–16th centuries Common Era (CE)] has for many years been understood as a “hydraulic city,” an urban complex defined, sustained,...Full Text Available
2007-09-04
The economic geology of clays/shales raw materials for the ceramics industry in Lebanon
International Nuclear Information System (INIS)
Author.Field, laboratory and market studies are a must for proper evaluation of natural resources for the mineral industry of lebanon. Sites selectively convenient to the existing major Lebanese ceramics industry centered in the Beqa'a region, were investigated as to their geology, geography and economic character. The raw materials are shales, mud stones, siltstones and other argillaceous rocks of Jurassic to Cretaceous age coming from selective sites in south and central Lebanon. The finished products include wall, floor, roofing tiles, pipes, sanitary ware, pottery and brick specimens. Differential thermal analysis, scanning electron microscopy, firing and physico-chemical tests and analyses characterized the raw materials into two major groups: the suitable are siliceous argillaceous rocks and unsuitable calcareous argillaceous rocks. The suitable group is divided into two varieties. The first is dominantly a disordered Kaolinite with low drying and firing ...
Energy Technology Data Exchange (ETDEWEB)
The authors have discovered chert xenoliths from green rocks in the Pippu area, central Hokkaido, Japan. Reports were given on the discovery with regard to the state of its production, chemical composition of the green rocks, and radiolarian fossils produced from the chert and their age. Considerations were given on the geological significance thereof. On 23 green rocks and five cherts out of the collected samples, rock slices were prepared, and petrographic statement was made by using a polarizing microscope. In addition, the whole petro-chemical composition analysis was performed on green rocks to discuss the radiolarian fossils and geological ages. The following conclusions were obtained as a result: green rocks may be identified as a product of igneous activities in a large plate in a certain period from the latter Callovian period of the middle age of the Jurassic period to the Barremian period of the Paleozoic era in the Cretaceous period; and their formation ...
1997-10-15
Introduction to neutron scattering for materials science
International Nuclear Information System (INIS)
The introduction prior to series of papers on the application of neutrons for materials science (MS) in this issue starts with a brief summary of neutron scattering research history in Japan; from the individual activity by Motoharu Kimura at RIKEN early around 1940s to those at present era of world leading neutron science facilities of both JRR3 research reactor and JPARC of the largest proton Accelerator complex in Tokai. Then physical properties of low energy neutrons applied to MS as well as such neutron sources are also reviewed (http://www.jstage.jst.go.jp/browse/jvsj2). (author)
2010-12-01
Innovative financing for future petroleum industry requirements
Energy Technology Data Exchange (ETDEWEB)
Many energies companies rely heavily on the financial markets to fund expansion plans due to the capital intensive nature of this industry. The dramatic and rapid changes in the financial markets over the last few years create both challenges and opportunities for oil and gas companies trying to survive a volatile era and to position themselves for recovery. These market volatilies have bred new financial techniques and opportunities in both the domestic and global capital markets. This paper discusses specific applications, benefits and advantages of these new techniques and financial products to energy companies.
1988-01-01
Feynman integral treatment of the Bargmann potential
International Nuclear Information System (INIS)
A method based on path integral formulation is given for obtaining exact solution of the s states for the Bargmann potentialV(r)=1ka"2#beta#(#beta#-1)e"-"2"r"/"a1-e"-"r"/"a"2-Ae"-"r"/"a1-e"-"r"/"a,where #beta# and k are parameters. The exact energy spectrum and the normalised s-state eigenfunctions are obtained from the poles of the Green function and their residues, respectively. The results are compared with their of Schrodinger formalism, special cases are also discussed.
2005-06-01
Energy planning in developing countries: the role of microcomputers
Energy Technology Data Exchange (ETDEWEB)
Microcomputers are beginning to be used for energy analysis in many developing countries, and have the potential for making a significant contribution to the resolution of difficult analytical and data problems, and to improving communications between analyst and decision maker. Successful introduction of a microcomputer based on analytical capability, however, requires attention to several important factors in order to avoid the mistakes of the earlier mainframe computer era. This paper reviews the key issues of matching models to staff capabilities, of training, and of the operating environment, based on the author's first-hand experience with microcomputer projects in Uruguay, Haiti and Sri Lanka. 3 figures, 3 tables.
1985-02-01
Pathological study on autopsy cases at Hiroshima Atomic Bomb Hospital, September 1956 - March 1988
Energy Technology Data Exchange (ETDEWEB)
A retrospective review was made of 2,659 autopsy patients obtained during the past 31 years and a half in Hiroshima Atomic Bomb Hospital. Of the patients, 1,328 (49.9%) were A-bomb survivors. Five hundred and six A-bomb survivors (38.1%) had been exposed at up to 2,000 m from the hypocenter. There was no correlation between the incidence of malignancy and the presence of exposure to A-bombing. The incidence of multiple malignancy was slightly higher in A-bomb survivors exposed at the place nearer the hypocenter. In the group of A-bomb survivors, cancer of the lung was the most common for men; and cancer of the stomach was the most common for women. The incidence of malignancy has been high in the exposed group during the early eras of examination; however, this figure has recently become high in the non-exposed group. Regarding the kinds of malignancy, there was no significant difference between the exposed and non-exposed groups. The incidence of leukemia was high ...
1990-03-01
Energy Technology Data Exchange (ETDEWEB)
Pyrolysis and combustion of CH are investigated. In order to reduce the work required for the present combination of parameters, the following substances were selected: Hexachloroethane, hexachlorocyclohexane, hexachlorobenzene and hexachlorophene. The model substances were pyrolyzed or combusted in varying conditions, and the combustion or pyrolysis products were analyzed. Only the main products were of interest; trace components are important only as far as they may throw light on the reaction mechanisms. The furnace design resulted in incomplete combustion and pyrolysis reactions, so that products of all stages of combusition or pyrolysis were available for analysis. Reaction processes can be derived from the products. As an alternative to thermal treatment of refuse, biological degradation of chlorinated hydrocarbons was gone into. The efficiency of decomposition by microorganisms was to be compared with the efficiency of thermal destruction of chlorohydrocarbons. The ...
1993-07-01
Worker radiation doses in the United States at the dawn of the atomic era (1940--1960)
Energy Technology Data Exchange (ETDEWEB)
Radiation doses to workers at the Manhattan Engineer District (MED) and US Atomic Energy Commission (AEC) sites due to external irradiation during 1940--1960 are reviewed. Categorized radiation dose data were available from AEC annual reports for some years. Annual individual radiation dose data for ten MED/AEC sites for all years were available from the US Department of Energy`s (DOE) Comprehensive Epidemiologic Data Resource (CEDR). These data are combined to produce an estimate of external collective dose equivalent to 172,000 person-rems (1720 person-Sv) for 1940--1960. During this period there were 41 overexposures, 19 criticality incidents, and 3 deaths due to acute radiation syndrome among several hundred thousand workers.
1994-06-01
British Library Electronic Table of Contents (United Kingdom)
Introduction: Tumor-derived heat shock protein (HSP)-peptide complexes (HSPPCs) induced immunity against malignancies in preclinical trials, working across tumor types and bypassing the need to identify single immunogenic peptides. These results paved the way for the use of human gp96 obtained from autologous tumor samples as an anti-cancer vaccine. Areas covered: Autologous tumor-derived HSP gp96 peptide complex (HSPPC-96) vaccine is emerging as a tumor- and patient-specific cancer vaccine, with confirmed activity in several malignancies. It has been tested in Phase III clinical trials in advanced melanoma and kidney cancer with evidence for efficacy in patients with earlier stage disease. HSPPC-96-based vaccine demonstrated an excellent safety profile, thus emerging as a novel therapeuti...
2011-01-01
British Library Electronic Table of Contents (United Kingdom)
Background Previous reports in adults have suggested that the effects experienced after cannabis use can be described in terms of positive and negative subtypes that are heritable and are associated with abuse and dependence. This study extends existing research by inclusion of adolescents and young adults in an offspring of twins design which makes it possible to take into account genetic and environmental risks for substance use disorder. Methods Data were collected from 725 twin members of the Vietnam Era Twin Registry, 839 of their 12-32 year old biological offspring and 427 mothers. Offspring who had ever used cannabis (n=464) were asked the degree to which they typically experienced 13 subjective effects shortly after using cannabis. Latent class analysis (LCA) was used to derive sub...
2009-01-01
British Library Electronic Table of Contents (United Kingdom)
The national research and development (R&D) base has in the post-cold war era gained increased importance in order to fill new security demands. There is a broadening of the search for security relevant science and technology involving more organizations and interests, scientific disciplines and nations. The question discussed in this article is if the premises of international, free and open R&D will be(come) compromised? Will we see more scientists, in their normal scientific activities, being accused of spying? The article suggests that such risks are not unrealistic to expect. Spy cases in less democratic countries could have consequences for scientists also in other countries. Outcomes depend on, among other things, the relative strengths of academic freedom and a political ...
2009-01-01
Revisited the mathematical derivation wall thickness measurement of pipe for radiography
Energy Technology Data Exchange (ETDEWEB)
Wall thickness measurement of pipe is very important of the structural integrity of the industrial plant. However, the radiography method has an advantage because the ability of penetrating the insulated pipe. This will have economic benefit for industry. Moreover, the era of digital radiography has more advantages because the speed of radiographic work, less exposure time and no chemical used for film development. Either the conventional radiography or digital radiology, the wall thickness measurement is using the tangential radiography technique (TRT). In case, of a large diameter, pipe (more than inches) the determination maximum penetration wall thickness must be taken into the consideration. This paper is revisited the mathematical derivation of the determination of wall thickness measurement based on tangential radiography technique (TRT). The mathematical approach used in this derivation is the Pythagoras theorem and geometrical principles. In order to ...
2007-07-01
Rabies in the Face of the 21st Century
British Library Electronic Table of Contents (United Kingdom)
Summary Reference to an ancient Hindu picture of a snarling dog may be a convincing enough proof to consider the fact that rabies has been known in the world for the past 50 centuries. Prior to the monumental observation about rabies of Fracastoro in the 16th century, facts and fantasies were intermingled in the study of rabies. In the realm of fantasy, consider the statement of Aristotle (otherwise a great philosopher) that only animals and not humans die of rabies. It took 19 centuries before Fracastoro finally established that infection with rabies is lethal for all warm-blooded beings including humans. The new era of rabies dates from the time of Galtier who isolated the virus and Pasteur who was able to create a somewhat attenuated strain of virus fixe which became the tool of laborat...
2009-01-01
Public power's roots deep in the Northwest
Energy Technology Data Exchange (ETDEWEB)
Municipal power systems developed early in the Pacific Northwest, but a new dimension was added in the 1930s when the public utility district (PUD) concept combining urban and rural areas encited vigorous debate and the public rejected private-utility candidates. A favorable national climate developed for consumer-owned systems during the 1920s and 30s encouraging the passage of the Federal Water Power Act, the creation of the Tennessee Valley Authority, the building of Hoover Dam, and the establishment of the Bonneville Power Administration. This article reviews developments following the Public Utility Act of 1935, which authorized the Federal Power Commission and the uniform system of accounts. After tracing the record of investigations and policy trends during the Roosevelt era, it concludes that utilities benefited from accounting regulations. (DCK)
1982-01-01
British Library Electronic Table of Contents (United Kingdom)
The term Process Systems Engineering (PSE) is relatively recent. It was coined about 50 years ago at the outset of the modern era of computer-aided engineering. However, the engineering of processing systems is almost as old as the beginning of the chemical industry, around the first half of the 19th century. Initially, the practice of PSE was qualitative and informal, but as time went on it was formalized in progressively increasing degrees. Today, it is solidly founded on engineering sciences and an array of systems-theoretical methodologies and computer-aided tools. This paper is not a review of the theoretical and methodological contributions by various researchers in the area of PSE. Its primary objective is to provide an overview of the history of PSE, i.e. its origin and evolution; ...
2011-01-01
On the Initiation Mechanism in Exploding Bridgewire and Laser Detonators
Since its invention by Los Alamos during the Manhattan Project era the exploding bridgewire detonator (EBW) has seen tremendous use and study. Recent development of a laser-powered device with detonation properties similar to an EBW is reviving interest in the basic physics of the deflagration-to-detonation (DDT) process in both of these devices. Cutback experiments using both laser interferometry and streak camera observations are providing new insight into the initiation mechanism in EBWs. These measurements are being correlated to a DDT model of compaction to detonation and shock to detonation developed previously by Xu and Stewart. The DDT model is incorporated into a high-resolution, multi-material model code for simulating the complete process. Model formulation and the modeling issues required to describe the test data will be discussed.
2006-07-01
Network selection in a WiMAX-WiFi environment
British Library Electronic Table of Contents (United Kingdom)
The tremendous growth of wireless technologies has introduced the potential of continuous service adaptation to the users' needs by giving them the ability to be able to select and access the proper network based on different criteria. Moreover, next generation wireless networks have been designed to provide support for multimedia services, with different traffic characteristics and different Quality of Service (QoS) guarantees. However, the expansion of Wireless Local Area Networks (WLANs) and Worldwide Interoperability for Microwave Access (WiMAX) networks poses new research era in the decision of the access network selection. In this paper, the existing access network selection schemes are classified into three categories: the network-centric, the user-centric and the collaborative sche...
2011-01-01
Metabolomic Study on the Halophyte Suaeda salsa in the Yellow River Delta
British Library Electronic Table of Contents (United Kingdom)
Abstract Plant metabolomics has been well established and applied across multiple fields including medicine, biotechnology, and environmental sciences in the post-genomic era. The Chenopodiaceae C3 halophyte Suaeda salsa is the most important plant species in the vegetation of saline soil and even intertidal zone in the Yellow River Delta, which is economically consumed as food, widely used as a bioindicator of environmental stresses (salinity, drought, and pollution) and typically applied for the phyto-remediation of degraded wetland. However, no global studies have been focused on the metabolic profile of this halophyte which is widely applied in environment related research areas. In metabolomics, the first crucial step is the preparation of plant samples. In this work, several strategi...
2011-01-01
Malaysian industry enters the gas era
Energy Technology Data Exchange (ETDEWEB)
Malaysia's petroleum industry is looking forward to an expansionary period until the end of the century, with the role of gas being greatly enhanced. The state oil firm Petronas sees increasing oil and gas reserves, making fuller use of abundant gas reserves, an exploration thrust into deepwater areas and the intensification of environmental protection as some of the points of emphasis in its current programme. The state firm president Tan Sri Datuk Azizan Zainul Abidin says that in the past few years a national economic growth rate of 8 percent has resulted in rising energy demand. Economic growth is projected to continue, so that an increase in power demand can be expected for the next few years. 'Fortunately, we are experiencing the same bullish trend in oil exploration and development,' he says. (author)
1992-12-01
Malaysian industry enters the gas era
International Nuclear Information System (INIS)
Malaysia's petroleum industry is looking forward to an expansionary period until the end of the century, with the role of gas being greatly enhanced. The state oil firm Petronas sees increasing oil and gas reserves, making fuller use of abundant gas reserves, an exploration thrust into deepwater areas and the intensification of environmental protection as some of the points of emphasis in its current programme. The state firm president Tan Sri Datuk Azizan Zainul Abidin says that in the past few years a national economic growth rate of 8 percent has resulted in rising energy demand. Economic growth is projected to continue, so that an increase in power demand can be expected for the next few years. 'Fortunately, we are experiencing the same bullish trend in oil exploration and development,' he says. (author).
Linking emerging hazardous waste technologies with the electronic information era
Energy Technology Data Exchange (ETDEWEB)
In looking to the future and the development of new approaches or strategies for managing hazardous waste, it is important to understand and appreciate the factors that have contributed to current successful approaches. In the United States, several events in the last two decades have had a significant impact in advancing remediation of hazardous waste, including environmental legislation, legislative reforms on licensing federally funded research, and electronic transfer of information. Similar activities also have occurred on a global level. While each of these areas is significant, the electronic exchange of information has no national boundaries and has become an active part of major hazardous waste research and management programs. It is important to realize that any group or society that is developing a comprehensive program in hazardous waste management should be able to take advantage of this advanced approach in the dissemination of information. 6 refs., 1 tab.
1996-12-31
Introduction to the Special Issue: Human Linkage Studies for Behavioral Traits
British Library Electronic Table of Contents (United Kingdom)
In the post Genome era, the aim of behavior genetics has shifted from estimating the relative contributions of genes and environmental factors to (co-)variation in human complex traits, to localization of genes and identification of functional genetic variants. This special issue reflects this transition and presents fifteen papers that report on genome-wide linkage scans for complex traits in humans and on methodological tools and innovations. Six papers focus on cognition and report overlapping linkage peaks on chromosomes 6p and 14p. Papers on addictive behavior, i.e. smoking and alcohol dependence and its endophenotypes, find moderate LOD scores on chromosomes 6p, 5q, 4p and 7q, respectively. Three papers concentrate on emotionality, depression and loneliness and examine chromosomes 2q...
2006-01-01
Gas turbine tops 40% efficiency; features novel inlet-air cooler
Energy Technology Data Exchange (ETDEWEB)
This article reports on the world's first gas turbine to top 40% thermal efficiency in simple cycle and is now operating commercially as part of a natural-gas-fired combined-cycle cogeneration (CC) plant serving the Ottawa Health Sciences Center, Ottawa, Ont, Canada. Owned and operated by TransAlta Energy Corp, Calgary, Alta, the CC plant supplies steam and hot and chilled water to the health center and another thermal user while the electricity is sold to Ontario Hydro. Part of the project included the conversion of 15-psig steam-carrying equipment to hot-water service. Commercial success of this installation heralds a new era in the application of efficient gas turbines for power generation.
1993-02-01
Cardiac Pacing: Memories of a Bygone Era
British Library Electronic Table of Contents (United Kingdom)
The first cardiac pacemaker implants occurred in the late 1950s and involved insertion of epicardial or epimyocardial leads and abdominal pulse generators. By the mid 1960s, cardiologists were making attempts to insert transvenous leads into the right ventricle. These early unipolar leads had large, polished, high polarization electrodes, no fixation device, and no lumen in which to place a stylet for lead positioning. The lead implantation procedures were usually long and the irradiation to both patient and operator excessive. Pulse generators were powered by zinc-mercury cells, which were large, unreliable, and prone to sudden output failure. Postoperative complications such as lead dislodgement, exit block, and premature power source failure were very common with most patients requiring...
2008-01-01
Brief laboratory report: surgical drape flammability.
Fires in the operating room continue to present a hazard to patients, at times with catastrophic and debilitating results. Recent data from closed claim files reveal oxygen, electrosurgical unit (ESU), and surgical drapes are common components of the fire triangle in the operating room. In this era of biotechnological sophistication, why are surgical drapes flammable? The purpose of this study was to test the flammability of different surgical drape materials and to determine the time to ignition using a bipolar ESU device in 21%, 35%, and 100% oxygen concentrations. Results show that regardless of oxygen concentration surgical drapes, when exposed to close contact with the ESU, are flammable. Time to ignition decreases with increasing concentrations of oxygen as expected. One of the surgical drapes tested was advertised to the hospital as nonflammable. Future research should focus on surgical drape materials and aim to reduce the flammability of such items in the ...
2006-10-01
British Library Electronic Table of Contents (United Kingdom)
Abstract Introduction.- Infection is the worst complication seen with inflatable penile prosthesis (IPP). Both the American Medical Systems (AMS) and Coloplast IPP have infection retardant coatings. AMS is coated at the factory with rifampicin and minocycline (InhibiZone). The Coloplast IPP has a hydrophilic coating covalently bonded to its components that will absorb any aqueous solution before implantation and provides increased surface lubricity to decrease bacterial adherence. Aim.- We tested several antibiotic dips comparing zones of inhibition (ZOI) against five commonly infecting bacteria with coated Coloplast implants. Results were compared with those ZOI created with strips of an AMS IPP precoated with InhibiZone. Methods.- Pieces of sterile Coloplast Titan IPP were dipped in (i) ...
2011-01-01
An overview of strategies to assess and rehabilitate former nuclear test sites. Keynote address
International Nuclear Information System (INIS)
Since the publication by the International Commission on Radiological Protection of revised recommendations which set out some general principles for intervention, some ideas have emerged which address interventions in the case of chronic exposure from contaminated lands. In the past there have been interventions proposed or carried out to rehabilitate land contaminated during the era of atmospheric nuclear weapon testing. Some of these interventions are reviewed in the context of these ideas and it is concluded that, by and large, reasonable outcomes have been achieved. The concept of a 'generic action level' (an effective dose of the order of 10 mSv#centre dot#a"-"1 to representative individuals in the critical group) may be useful in future to aid decision makers in determining whether intervention is appropriate. (author)
An enhanced model framework of personalized material flow services
British Library Electronic Table of Contents (United Kingdom)
A growing concern about the consumer behavior in Internet economy has spurred the study of Material Flow, resulting in a unique type of consumer behavioral analysis. This research proposes an enhanced conceptual model for Personalized Material Flow Services for consumer behavior. In the era of Internet information technology, customer?s taste tends to be personalized for their market demand. It is observed that there are number of ?Long Tail? phenomena in several successful e-commerce business cases. However, the Long Tail phenomenon is an open question for our research in terms of its role in e-commerce marketing. In the proposed model-X-Party Personalized Material Flow Services, three elements are discussed. They are ?providing?, ?locating? and ?obtaining? based on X-Party Material Flow ...
2011-01-01
Algorithms for Internal Validation Clustering Measures in the Post Genomic Era
Inferring cluster structure in microarray datasets is a fundamental task for the -omic sciences. A fundamental question in Statistics, Data Analysis and Classification, is the prediction of the number of clusters in a dataset, usually established via internal validation measures. Despite the wealth of internal measures available in the literature, new ones have been recently proposed, some of them specifically for microarray data. In this dissertation, a study of internal validation measures is given, paying particular attention to the stability based ones. Indeed, this class of measures is particularly prominent and promising in order to have a reliable estimate the number of clusters in a dataset. For those measures, a new general algorithmic paradigm is proposed here that highlights the richness of measures in this class and accounts for the ones already available in the literature. Moreover, some of the most representative validation measures are also considered. Experiments on 12 ...
2011-01-01
1 The German National Analysis Facility as a tool for ATLAS analyses
In 2008 the German National Analysis Facility (NAF) at DESY was established. It is attached to and builds on top of DESY Grid infrastructure. The facility is designed to provide the best possible analysis infrastructure for high energy particle physics of the ATLAS, CMS, LHCb and ILC experiments. The Grid and local infrastructure of the NAF is reviewed with a focus on the ATLAS part. Both parts include large scale storage and a batch system. Emphasis is put on ATLAS specific customisation and utilisation of the NAF. This refers not only to the NAF components but also to the di erent components of the ATLAS analysis framework. Experience from operating and supporting ATLAS users on the NAF is presented in this paper. The ATLAS usage of the di erent components are shown including some typical use cases of user analysis. Finally, the question is addressed, if the design of the NAF meets the ATLAS expectations for effcient data analysis in the era of LHC data taking.
2011-01-01
Hot, flat and crowded. Why we need a green revolution - and how it can renew America
International Nuclear Information System (INIS)
The author blows the whistle about what he considers as a worldwide environmental crisis. He brings a fresh outlook to the crises of destabilizing climate change and rising competition for energy - both of which could poison our world if we do not act quickly and collectively. His argument speaks to all of us who are concerned about the state of America in the global future. The author proposes that an ambitious national strategy - which he calls 'Geo-Greenism' - is not only what we need to save the planet from overheating; it is what we need to make America healthier, richer, more innovative, more productive, and more secure. He explains a new era - the Energy-Climate era - through an illuminating account of recent events. He shows how 9/11, Hurricane Katrina, and the flattening of the world by the Internet (which brought 3 billion new consumers onto the world stage) have combined to bring climate and energy issues to Main Street. But they ...
Best of the lot : engineered measurement-while-drilling tool improves efficiency of operations
Energy Technology Data Exchange (ETDEWEB)
NuEra Oilfield Services Inc. combines various technologies, including advanced bearing assemblies and compact wireless decoders that interface with downhole directional tools, to engineer unique, purpose-built measurement-while-drilling (MWD) tool string packages. The 9-metre-long MWD tool string is lowered into the drill pipe from the surface. The directional module monitors the position of the drill bit, which the driller can monitor using an electronic drilling recorder at the surface. The directional drillstring uses a mud motor with adjustable bent housing to correct the direction of the well, as the system cannot steer while drilling. At bottomhole, mud circulation continues after the rotation of the drillstring has been stopped, driving the mud motor, which in turn drives the drill bit, permitting a new direction to be taken even though the drillstring is not turning. The operator points the bent housing in a new direction and slides the bit along before ...
2010-10-15
We conducted a retrospective review of the North American Renal Transplant Cooperative Study (NAPRTCS) Registry transplant and dialysis arms to assess anemia and growth patterns in children who returned to dialysis after a failed renal transplant from January 1, 1992 to February 3, 2004. Of the 1807 potential study subjects, 1451 had transplant removal data (TxIn vs. TxOut) available for analysis. Four hundred and twenty-one of 1451 patients (29%) had a transplant nephrectomy at the time of entry into the NAPRTCS Registry Dialysis arm. Anemia rates steadily decreased from 72.2% at 30 days after dialysis initiation to 59.5% at 12 months after dialysis initiation. Factors associated with anemia at 30 days after dialysis initiation included hemodialysis, lack of Epo use, and patients who comprised earlier study era cohorts. At one yr after return to dialysis, earlier study cohort era was the only factor associated with anemia status. Patients did ...
2007-03-01
The compact linear collider CLIC
A high luminosity (10e34 - 10e35 cm square/s) electron-positron Collider (CLIC) with a nominal centre-of-mass energy of 3 TeV has been under study for a number of years at CERN within an international collaboration of laboratories and institutes to provide the HEP community with a new accelerator-based facility for the post-LHC era. In order to achieve the very high design luminosity, very low emittance beams have to be produced and focused down to very small beam sizes at the interaction point. Beam acceleration using high frequency normal-conducting structures operating at high accelerating fields significantly reduces the length and, in consequence, the cost of the linac. The overall length of the 3 TeV collider is about 33 km. The goals of the CLIC scheme are ambitious, and require further R&D to demonstrate that they are indeed technically feasible. A new test facility is being built at CERN for this purpose with the aim to demonstrate the key feasibility ...
2004-01-01
ScotGrid: Providing an Effective Distributed Tier-2 in the LHC Era
ScotGrid is a distributed Tier-2 centre in the UK with sites in Durham, Edinburgh and Glasgow. ScotGrid has undergone a huge expansion in hardware in anticipation of the LHC and now provides more than 4MSI2K and 500TB to the LHC VOs. Scaling up to this level of provision has brought many challenges to the Tier-2 and we show in this paper how we have adopted new methods of organising the centres, from fabric management and monitoring to remote management of sites to management and operational procedures, to meet these challenges. We describe how we have coped with different operational models at the sites, where Glagsow and Durham sites are managed "in house" but resources at Edinburgh are managed as a central university resource. This required the adoption of a different fabric management model at Edinburgh and a special engagement with the cluster managers. Challenges arose from the different job models of local and grid submission that required special attention to resolve. We show ...
2009-01-01
Optimal Weak Lensing Skewness Measurements
Weak lensing measurements are entering a precision era to statistically map the distribution of matter in the universe. The most common measurement has been of the variance of the projected surface density of matter, which corresponds to the induced correlation in alignments of background galaxies. This measurement of the fluctuations is insensitive to the total mass content, like using waves on the ocean to measure its depths. But when the depth is shallow as happens near a beach, waves become skewed. Similarly, a measurement of skewness in the projected matter distribution directly measures the total matter content of the universe. While skewness has already been convincingly detected, its constraint on cosmology is still weak. We address optimal analyses for the CFHT Legacy Survey in the presence of noise. We show that a compensated Gaussian filter with a width of 2.5 arc minutes optimizes the cosmological constraint, yielding $\\Delta \\Omega_m/\\Omega_m\\sim ...
2003-01-01
New era for coal-based electricity generation in the United States
Energy Technology Data Exchange (ETDEWEB)
In 1970, the Federal Power Commission predicted a fall from 46% to 27% in 1990 as a result of predicted increases in the use of nuclear power. Today, the Department of Energy expects coal to supply about 50% of electricity generation in 1990. About one-eighth of the world's annual hard coal production is used to make electricity in the United States. Power stations in the country used more coal in 1979 than was produced in the whole Western Europe that year. These 405,000,000 tons of coal equivalent were burned in 1257 individual utilities with an aggregate capacity of 235,000 megawatts. There are coal-fired power plants in 43 of the 50 states. Four factors will be most important in shaping the future development of coal-based electricity: prices, conservation, environmental regulations, and national security. The price differential between coal and oil has now reached a level where it is much more economic for a United States electric utility to build and operate a new ...
1980-01-01
Industry Expectations from New Construction Engineers and Managers: Curriculum Improvement
In an era of unprecedented technological advancement and economic expansion, construction practice continues to evolve but construction education has not changed appreciably since the 1990s. This schism has prompted industry, government, and other key constituents to question the relevancy and efficacy of current programs. The Accreditation Board for Engineering and Technology (ABET) Engineering Criteria 2000 and the American Council for Construction Education (ACCE) emphasizes outcomes over process, and provides an opportunity for stakeholders to help universities define educational goals and objectives and design a curriculum to meet the desired outcomes. While the need for curriculum modification has been acknowledged, the industry position was amorphous and anecdotal and therefore difficult to address. Qualitative methodologies such as formal surveys and structured interviews can be used to capture and quantify industry expectations of the needed attributes ...
2009-10-14
Energy Technology Data Exchange (ETDEWEB)
The aim of our project is to develop high-performance processor architectures for both general purpose and application-specific purpose. We also plan to develop basic softwares, such as compliers, and various design aid tools for those architectures. We are particularly interested in performance evaluation at architecture design phase, design optimization, automatic generation of compliers from processor designs, and architecture design methodologies combined with circuit layout. We have investigated both microprocessor architectures and design methodologies / environments for the processors. Our goal is to establish design technologies for high-performance, low-power, low-cost and highly-reliable systems in system-on-silicon era. We have proposed PPRAM architecture for high-performance system using DRAM and logic mixture technology, Softcore processor architecture for special purpose processors in embedded systems, and Power-Pro architecture for low power systems. ...
1997-03-01
Evolution of a molecular switch: universal bacterial GTPases regulate ribosome function.
The GTPases comprise a protein superfamily of highly conserved molecular switches adapted to many diverse functions. These proteins are found in all domains of life and often perform essential roles in fundamental cellular processes. Analysis of data from genome sequencing projects demonstrates that bacteria possess a core of 11 universally conserved GTPases (elongation factor G and Tu, initiation factor 2, LepA, Era, Obg, ThdF/TrmE, Ffh, FtsY, EngA and YchF). Investigations aimed at understanding the function of GTPases indicate that a second conserved feature of these proteins is that they elicit their function through interaction with RNA and/or ribosomes. An emerging concept suggests that the 11 universal GTPases are either necessary for ribosome function or transmitting information from the ribosome to downstream targets for the purpose of generating specific cellular responses. Furthermore, it is suggested that progenitor GTPases were early regulators of RNA ...
2001-07-01
Energy Technology Data Exchange (ETDEWEB)
Managing sites contaminated with munitions constituents is an international challenge. Although the choice of approach and the use of Ecological Risk Assessment (ERA) tools may vary from country to country, the assurance of quality and the direction of ecotoxicological research are universally recognized as shared concerns. Drawing on a multidisciplinary team of contributors, 'Ecotoxicology of Explosives' provides comprehensive and critical reviews available to date on fate, transport, and effects of explosives. The book delineates the state of the science of the ecotoxicology of explosives, past, present, and recently developed. It reviews the accessible fate and ecotoxicological data for energetic materials (EMs) and the methods for their development. The chapters characterize the fate of explosives in the environment, then provide information on their ecological effects in key environmental media, including aquatic, sedimentary, and terrestrial ...
2009-04-01
Design of multifunction anti-terrorism robotic system based on police dog
Aimed at some typical constraints of police dogs and robots used in the areas of reconnaissance and counterterrorism currently, the multifunction anti-terrorism robotic system based on police dog has been introduced. The system is made up of two parts: portable commanding device and police dog robotic system. The portable commanding device consists of power supply module, microprocessor module, LCD display module, wireless data receiving and dispatching module and commanding module, which implements the remote control to the police dogs and takes real time monitor to the video and images. The police dog robotic system consists of microprocessor module, micro video module, wireless data transmission module, power supply module and offence weapon module, which real time collects and transmits video and image data of the counter-terrorism sites, and gives military attack based on commands. The system combines police dogs" biological intelligence with micro robot. Not only does it avoid ...
2007-11-01
Creep-rupture, creep strength and tensile data on Alloy 800 between 500-800"0C
International Nuclear Information System (INIS)
The authors present tensile data and creep-rupture data out to approximately 40,000 h duration on low-carbon Alloy 800. Each of the four casts was heat treated to three conditions in tube form. When the test programme was originally conceived, the prime object was to obtain 100,000 hour design data; the programme was designed prior to some of the more recently discovered effects such as that of #gamma#' on ductility. Therefore no specific attempt was made to control to a low level, the Al and Ti contents of the casts. A subsequent programme was embarked upon in 1976 where these factors were taken into account. The bulk data obtained show many characteristics which are probably typical of the low-carbon variant of this material and both the quantity and duration of the data are a contribution to the knowledge of the long-term behaviour of this class of alloy, whose future use lies, inter alia, in nuclear applications over the temperature range for which ERA data ...
The relevance of the teacher to the success of any education innovation is not open to contention. Equally incontentious is the relevance of education and training to the success of the teacher in the attainment of his/her professional goals. It is against this background that this paper examines the continuing education imperatives in the present basic education crusade in Nigeria. Here continuing education is conceptualized as a process for developing teacher's skill for coping with changing demands of the job through regular exposure to professional renewal programmes. The paper contends that inasmuch as the teacher will continue to play a pivotal role in the execution of educational innovations, then further education and training as it affects him/her must receive priority attention in the conceptualization and implementation of such innovations. To this end, the paper advocates: teacher exchange programmes between Nigeria and other countries of the world; establishment of ...
2003-12-01
On the Role of Convection and Turbulence for Tropospheric Ozone and its Precursors
International Nuclear Information System (INIS)
The aim of the work in this thesis is to investigate the convective and diffusive transport in the TM chemistry transport model, and to investigate some aspects of the consequences for NOx. The large inaccuracy and uncertainty in the description of processes like convection and turbulent diffusion, the strong dependence of the radiative forcing of ozone on its vertical distribution, and the strong dependence of the ozone production on the distribution of NOx, are the main motivation. The availability of the ERA-40 data, where convective data and vertical diffusion coefficients are archived, allows a study of the effect of different convective mass flux sets, and different vertical diffusion coefficients on the model-simulated distribution of tracers. In this thesis the following questions are addressed : (1) How large is the sensitivity of the (model simulated) distribution of ozone and nitrogen oxides on (the) convection (parameterisation)?; (2) What requirements ...
Unusual Recharge Processes near Arroyos of the Rio Grande Aquifer, El Paso/Juarez Area
The twin-cities of El Paso and Juarez share the water resources of the Hueco Bolson aquifer and overlying Rio Grande aquifer. Both aquifers span the international border between Mexico and the United States. Salinity in the Rio Grande aquifer varies widely, some parts of the shallow aquifer containing less than 1,000 mg/L total dissolved solids (TDS), other parts of the aquifer exceeding 5,000 mg/L TDS. One sizable part of the "Lower Valley" area, approximately 45 km below El Paso contains very dilute water near the outer edge of the floodplain. Historically it had been thought that the dilute waters in this location were derived from recharge from arroyos that drained proximal parts of the Hueco Bolson. Instead, our hydrogen and oxygen isotope data and carbon-14 data indicate that these dilute waters were derived from pre-dam infiltration of the Rio Grande. Relatively light and slightly evaporated pre-dam waters (-11.5 del O18) at the arroyos are also relatively young (60 to 90 ...
2005-12-01
Transcriptional regulation in Drosophila: the post-genome challenge.
Drosophila melanogaster has long been at the forefront of studies of transcriptional regulation in animals. Many fundamental ideas--such as cis control elements that act over long distances, the regulation of development by hierarchical cascades of transcription factors, dosage compensation, and position effect variegation--originated from studies of the fruit fly. The recent completion of the euchromatic DNA sequence of Drosophila is another breakthrough. The sequence data highlight important unanswered questions. For example, only one-fifth of the 124 Mb of Drosophila euchromatic DNA codes for protein. The function of the remaining 100 Mb of mostly unique DNA is largely unknown. Some proportion of this non-reading frame DNA must encode the functional recognition sites targeted by the approximately 700 sequence-specific DNA binding proteins that regulate transcription in Drosophila, but what proportion? Most or very little? Promoter sequences by definition contain all of the cis ...
2001-03-01
Energy Technology Data Exchange (ETDEWEB)
In its beginning, the U.S. Department of Energy (DOE) Office of Environmental Management (EM) viewed private industry as lacking adequate technology know-how to meet demands of hazardous and radioactive waste problems at the DOE`s laboratories and nuclear weapons production facilities. In November 1989, EM`s Office of Technology Development (recently renamed the Office of Science and Technology) embarked on a bold program of developing and demonstrating {open_quotes}innovative{close_quotes} waste cleanup technologies that would be safer, faster, more effective, and less expensive than the {open_quotes}baseline{close_quotes} commercial methods. This program has engaged DOE sites, national laboratories, and universities to produce preferred solutions to the problems of handling and treating DOE wastes. More recently, much of this work has shifted to joint efforts with private industry partners to accelerate the use of newly developed technologies and to enhance existing commercial ...
1996-12-31
START: An essential step in a new era
Energy Technology Data Exchange (ETDEWEB)
After more than nine years of negotiations, the US and the Soviet Union signed the Strategic Arms Reduction Treaty (START) in Moscow on July 31, 1991. While the world has changed dramatically since 1982 when the START negotiations began, the treaty remains very much in the US interest. START exacts deep cuts in the most destabilizing and dangerous US and Soviet strategic weapons, and will lead to substantial overall reductions in the strategic nuclear forces of both sides. Moreover, the agreement will create a formal, structured, and predictable strategic environment. It will also impose on the Soviet Union or its successors a legally binding set of obligations that will be in effect for many years, regardless of changes in leadership or form of government. START, with its extensive series of intrusive, cooperative, and technical verification measures, will greatly enhance US knowledge about Soviet strategic nuclear forces and activities. The force reductions, predictability, and ...
1991-11-01
Renal artery stenosis after radiotherapy for Ewing's sarcoma
International Nuclear Information System (INIS)
Background: the fact that therapeutic irradiation can induce significant stenosis in the arteries of the head, neck, and chest, as welt as in the aorta and the iliac arteries, is familiar in daily practice and well documented in the literature. By contrast, radiation-induced renal artery stenosis seems to be a less widely known complication. Patients and methods: the sudden onset of medically refractory arterial hypertension and coma in a 27-year-old man is reported, who had been treated at age 20 with chemotherapy and radiotherapy for Ewing's sarcoma in the lumbar region. This treatment had been performed at the hospital of Sion, Switzerland in 2001. Also, the relevant literature from 1965 to 2007 is reviewed to underscore various aspects of this problem and to demonstrate the clinical relevance of renal artery stenosis as a potential long-term sequela of radiotherapy. Conclusion: radiation-induced renal artery stenosis has only rarely been described in the literature, but arterial ...
2008-09-01
Energy Technology Data Exchange (ETDEWEB)
This Remedial Investigation (RI) Work Plan specifically addresses Chestnut Ridge Operable Unit 1, (OU1) which consists of the Chestnut Ridge Security Pits (CRSP). The CRSP are located {approximately}800 ft southeast of the central portion of the Y-12 Plant atop Chestnut Ridge, which is bounded to the northwest by Bear Creek Valley and to the southeast by Bethel Valley. Operated from 1973 to 1988, the CRSP consisted of a series of trenches used for the disposal of classified hazardous and nonhazardous waste materials. Disposal of hazardous waste materials was discontinued in December 1984, while nonhazardous waste disposal ended on November 8, 1988. An RI is being conducted at this site in response to CERCLA regulations. The overall objectives of the RI are to collect data necessary to evaluate the nature and extent of contaminants of concern (COC), support an ecological risk assessment (ERA) and a human health risk assessment (HHRA), support the evaluation of ...
1993-09-01
Radiation therapy for Ewing's sarcoma: Results from Memorial Sloan-Kettering in the modern era
International Nuclear Information System (INIS)
Purpose: To evaluate the outcomes of patients with Ewing's sarcoma family of tumors (ESFT) treated with modern radiotherapy techniques with MRI along with optimal chemotherapy. Methods and Materials: The records of all 60 patients with ESFT who received radiation to the primary site between 1990 and 2004 were reviewed. All patients received chemotherapy, including vincristine, doxorubicin, cyclophosphamide, ifosfamide, and etoposide. Radiation was used as the sole modality for local control in 31 patients and was given either before (n = 3) or after surgical resection (n = 26) in the remainder. All patients had MRI and CT scan-based treatment planning, and 43% received intensity-modulated radiation therapy. Radiation doses ranged from 30 Gy to 60 Gy (median, 51 Gy), and 35% received hyperfractionated radiotherapy. Results: Median age was 16 years (range, 2-40 years). Because of selection bias for radiotherapy, the majority of primary tumors were centrally located (72%): spine (n = 18), ...
2006-02-01
The first sediments to onlap the metamorphosed Precambrian Arabian shield were Infracambrian (Proterozoic) to Middle Cambrian carbonates, clastics, and evaporites. The oldest Arabian reservoir rocks occur in the Precambrian to lower Paleozoic Era Salt of the Huqf Group, which forms the Birba field of Oman. The Middle Cambrian sequence was followed by Late Cambrian through Early Permian marine sandstones and continental to littoral siltstones and variegated shales. The first commercial oil discovered in the Arabian Gulf region occurs in fluvial sands of the Ordovician to Permian Haima and Haushi Groups of the Marmul field in south Oman. These strata are also productive in other fields and are sealed by unconformable contact with the Al Khlata Formation or beneath shale of the Albian Nahr Umr Formation. The deeply buried kerogen sediments of the Huqf Group to the southeast are believed to be the source rocks for these fields of south Oman. The Late Permian to ...
1986-08-01
We evaluated 190 children with very high-risk leukemia, who underwent allogeneic hematopoietic cell transplantation in 2 sequential treatment eras, to determine whether those treated with contemporary protocols had a high risk of relapse or toxic death, and whether non-HLA-identical transplantations yielded poor outcomes. For the recent cohorts, the 5-year overall survival rates were 65% for the 37 patients with acute lymphoblastic leukemia and 74% for the 46 with acute myeloid leukemia; these rates compared favorably with those of earlier cohorts (28%, n = 57; and 34%, n = 50, respectively). Improvement in the recent cohorts was observed regardless of donor type (sibling, 70% vs 24%; unrelated, 61% vs 37%; and haploidentical, 88% vs 19%), attributable to less infection (hazard ratio [HR] = 0.12; P = .005), regimen-related toxicity (HR = 0.25; P = .002), and leukemia-related death (HR = 0.40; P = .01). Survival probability was dependent on leukemia status (first ...
2011-05-25
Energy Technology Data Exchange (ETDEWEB)
'Energy Nation Norway' looks at Norway as an energy nation from both a national and an international perspective. Its purpose is to provide a basis for political and industrial decisions relating to the petroleum industry. The report is particular concerned with the petroleum sector, besides considering the Norwegian energy cluster from a broader perspective. The energy cluster has been and will continue to be a crucial vehicle for economic growth and the development of wealth in Norway. These are the report's main conclusions: The petroleum industry has played a significant part in Norway's economic development, the side-effects of which have benefited the country's entire population. The world's economic growth and wealth development require energy. In the next few decades oil and gas will continue to form a large part of the world's energy consumption. Norway has great opportunities and competitive advantages over other ...
2008-07-01
Ecological risk assessment of the east branch, Finniss River
International Nuclear Information System (INIS)
Quantitative ecological risk assessment (ERA) is a means whereby the risk posed by a toxicant in any system can be evaluated by comparing the distribution of its measured or modelled concentrations (water quality data (WQD)) with available information on the range of concentrations that are known to adversely affect biota within that, or similar, habitats (dose-response data (DRD)). Initially, the WQD are compared with regulatory criteria (e.g. ANZECC and ARMCANZ, 2000). If they fail this test, then, on the assumption that both data sets comprise subsets of the entire range of concentrations, probability density functions are derived assuming a standard distribution form a typically log-normal. In this paper, AQUARISK has been used to estimate the risk posed by copper in effluent from the Rum Jungle mine site, pre- and post-remediation, and the proportion of taxa likely to be affected in the East Branch (EB) of the Finniss River downstream of the mine. In addition, ...
2002-03-01
Asymptomatic cholelithiasis is increasingly diagnosed today, mainly as a result of the widespread use of abdominal ultrasonography for the evaluation of patients for unrelated or vague abdominal complaints. About 10-20% of people in most western countries have gallstones, and among them 50-70% are asymptomatic at the time of diagnosis. Asymptomatic gallstone disease has a benign natural course; the progression of asymptomatic to symptomatic disease is relatively low, ranging from 10-25%. The majority of patients rarely develop gallstone-related complications without first having at least one episode of biliary pain ("colic"). In the prelaparoscopy era, (open) cholecystectomy was generally performed for symptomatic disease. The minimally invasive laparoscopic cholecystectomy refueled the discussion about the optimal management of asymptomatic cholelithiasis. Despite some controversy, most authors agree that the vast majority of subjects should be managed by ...
2007-03-28
Using histopathologic diagnoses made on necropsy material from 3,024 military working dogs (MWDs) who died from 1968 to 1973, we analyzed the effect of military service in the Republic of Vietnam on testicular pathology. Among 1,048 MWDs that died in Vietnam and had no reported developmental risk factors for testicular disease, significant excesses of testicular hemorrhage, epididymitis/orchitis, sperm granuloma, testicular degeneration, and seminoma were evident. Among 126 MWDs with prior Vietnam service who died at other duty stations outside Vietnam from 1968 to 1973, significant excesses of testicular degeneration and seminoma were likewise evident. Among 136 MWDs with prior Vietnam service that later died from 1974 to 1980, seminoma continued to be diagnosed in significant excess. In each instance, the odds ratio for the association between Vietnam service and seminoma was 2.0 or greater. Analysis of ever service by Corps Tactical Zones showed significant excesses of seminoma with ...
1995-05-01
Energy Technology Data Exchange (ETDEWEB)
Our modern society is increasingly faced with challenges and problems that cannot be solved by a purely technical, political or social approach. Radioactive waste disposal site selection and management can be characterised as one of these challenges that require a transdisciplinary approach, integrating social, philosophical and ethical aspects in a 'technical' practice. Along the spirit of this transdisciplinary approach, and in order to ensure the necessary public support for a policy decision regarding this practice, stakeholder involvement is more and more seen as a necessary policy element in the decision making process. The aim is to achieve the broad involvement of individuals from civil society, with significant representation from local communities, elected representatives and NGO's, as well as scientists from outside radioactive waste management organisations, together with established players in the field, such as the implementers of radioactive ...
2006-09-15
Education for All by 2015: Will We Make It?
Seven years ago 164 governments, together with partner organizations from around the world, made a collective commitment to dramatically expand educational opportunities for children, youth, and adults by 2015. Participants at the World Education Forum in Dakar, Senegal, endorsed a comprehensive vision of education, anchored in human rights, affirming the importance of learning at all ages and emphasizing the need for special measures to reach the poorest, most vulnerable and most disadvantaged groups in society. This sixth edition of the "Education for All (EFA) Global Monitoring Report" assesses the extent to which these commitments are being met. There is clearly a "Dakar effect," evidence that rallying around common goals can mobilize countries to empower individual lives. Partly because of the abolition of tuition fees, more children are enrolled in school than in 2000, with the sharpest increases in the regions farthest from the goals set in Dakar. Many governments have ...
2006-12-01
The Earth in energy troubles; La Planete en mal d'energie
Energy Technology Data Exchange (ETDEWEB)
This document gathers the available presentations (articles and transparencies) given at this annual meeting, the 2007 topic of which was the technological, geopolitical, economical, environmental, societal and development stakes of energy. 1 - technological stakes - which energies for the future: new energies, illusion or solution of the future; the Lorraine region, an energy land: strategies and stakes for a sustainable development; from China to Brazil: understanding the nuclear energy revival; hydroelectric power: renewable and sustainable energy; renewable energies and environment protection: the contribution of biofuels; wind power in Germany between success and contestation; 2 - geopolitical stakes - energy levier of power: the Gulf of Guinea hydrocarbons: between development and geopolitics; the complex evaluation of resources and reserves between technology, market and geopolitics; the new Bakou-Tbilissi-Ceyhan pipeline: what impacts for Turkey and the European Union; 3 - ...
2007-07-01
An analysis strategy for safeguards use of optical satellite imagery
International Nuclear Information System (INIS)
This paper outlines conceptual framework for safeguards remote sensing, and suggests a strategy for overcoming the challenges to full exploitation of all types of optical satellite imagery. Since the introduction of commercial open-source high-resolution satellite imagery in 1999, it has become an important tool for verification of declarations, baseline mapping, detection and monitoring of changes and investigation of undeclared activities. Its use is still relatively restricted, but there is a growing demand for wider satellite reconnaissance support, and the Satellite Image Analysis Unit (SIAU) has recently been expanded in response. For a number of reasons, IAEA safeguards use of satellite imagery is largely based on visual interpretation by experienced image analysts of high-resolution monochromatic imagery to monitor and characterize buildings and structures on safeguards sites. The very wide range of remote sensing capabilities could be more fully exploited. There is still a ...
2006-10-16
Advanced applications of water cooled nuclear power plants
International Nuclear Information System (INIS)
By August 2007, there were 438 nuclear power plants (NPPs) in operation worldwide, with a total capacity of 371.7 GW(e). Further, 31 units, totaling 24.1 GW(e), were under construction. During 2006 nuclear power produced 2659.7 billion kWh of electricity, which was 15.2% of the world's total. The vast majority of these plants use water-cooled reactors. Based on information provided by its Member States, the IAEA projects that nuclear power will grow significantly, producing between 2760 and 2810 billion kWh annually by 2010, between 3120 and 3840 billion kWh annually by 2020, and between 3325 and 5040 billion kWh annually by 2030. There are several reasons for these rising expectations for nuclear power: - Nuclear power's lengthening experience and good performance: The industry now has more than 12 000 reactor years of experience, and the global average nuclear plant availability during 2006 reached 83%; - Growing energy needs: All forecasts project increases in world energy demand, ...
2007-07-01
Advanced applications of water cooled nuclear power plants
International Nuclear Information System (INIS)
By August 2007, there were 438 nuclear power plants (NPPs) in operation worldwide, with a total capacity of 371.7 GW(e). Further, 31 units, totaling 24.1 GW(e), were under construction. During 2006 nuclear power produced 2659.7 billion kWh of electricity, which was 15.2% of the world's total. The vast majority of these plants use water-cooled reactors. Based on information provided by its Member States, the IAEA projects that nuclear power will grow significantly, producing between 2760 and 2810 billion kWh annually by 2010, between 3120 and 3840 billion kWh annually by 2020, and between 3325 and 5040 billion kWh annually by 2030. There are several reasons for these rising expectations for nuclear power: - Nuclear power's lengthening experience and good performance: The industry now has more than 12 000 reactor years of experience, and the global average nuclear plant availability during 2006 reached 83%; - Growing energy needs: All forecasts project increases in world energy demand, ...
1996-07-21
Advanced applications of water cooled nuclear power plants
International Nuclear Information System (INIS)
By August 2007, there were 438 nuclear power plants (NPPs) in operation worldwide, with a total capacity of 371.7 GW(e). Further, 31 units, totaling 24.1 GW(e), were under construction. During 2006 nuclear power produced 2659.7 billion kWh of electricity, which was 15.2% of the world's total. The vast majority of these plants use water-cooled reactors. Based on information provided by its Member States, the IAEA projects that nuclear power will grow significantly, producing between 2760 and 2810 billion kWh annually by 2010, between 3120 and 3840 billion kWh annually by 2020, and between 3325 and 5040 billion kWh annually by 2030. There are several reasons for these rising expectations for nuclear power: - Nuclear power's lengthening experience and good performance: The industry now has more than 12 000 reactor years of experience, and the global average nuclear plant availability during 2006 reached 83%; - Growing energy needs: All forecasts project increases in world energy demand, ...
2007-11-23
A decade of petroleum developments
Energy Technology Data Exchange (ETDEWEB)
Canada's offshore Atlantic petroleum industry is celebrating its tenth anniversary in 2001. This article chronicles the development of the industry discussing the many challenges and setbacks and the eventual triumphs that accompanied the industry's development over the years. Highlights discussed include shipping first oil from the Cohasset Field in July 1992; the financial crisis caused by the withdrawal of Gulf Oil from the Hibernia consortium in the same year; new funding and the beginning of the gravity-based structure construction at Bulls Arm in 1993; striking oil in the Hibernia Field in 1994; the start of exploration and development of the Terra Nova field by Petro-Canada in the same year, based on the floating production, storage and offloading (FPSO) system, which heralded a new era of offshore development in eastern Canada. Approval by the Nova Scotia government of the third and final phase of the Sable Offshore Energy Project followed ...
2001-03-01
Energy Technology Data Exchange (ETDEWEB)
Historically the organizational models have followed an evolution that has underlined a parallel trend to the complexity of the market, introducing as different mechanisms of coordination. Up to yesterday the winning model it was that hierarchical that however it is not certainly immune from limits. Beginning from eight hundred and especially in the nine hundred experts of organization have studied an alternative or supplementary model to that hierarchical: the bureaucratic model. This last entrusts the organization of the firm to the norms and the procedures considering them like the best integrating mechanism of development of the organizations. Today it is not made that to speak of the model to net, but it would be a serious error if this had to a substitutive model thought of the precedents, that can work then without hierarchy and without alone procedures entirely thanks to the use of Internet. In the present job are individualized new models of management of the private firms and ...
2001-07-01
Gastric stromal tumors. CT findings; Tumori stromali gastrici. Aspetti con Tomografia Computerizzata
Energy Technology Data Exchange (ETDEWEB)
Gastric stromal tumors are an ill-defined group of lesions arising from muscle wall cells and characterized by extremely variable biological patterns. Thanks to modern immunohistochemical and ultrastructural techniques, four main classes of these lesions have been identified, namely: (1) tumors with differentiation toward smooth muscle cells; (2) tumors with differentiation toward neural elements; (3) tumors with differentiation toward neural elements; (3) tumors with dual differentiation toward either cell type. It was investigated the yield of CT in diagnosing and characterizing gastric stromal tumors. It was retrospectively reviewed the CT findings of 38 patients (15 men and 23 women; mean age 51 years) with pathologically proven gastric stromal tumors, namely 31 of myoid origin, 4 of neural origin, 2 with both muscle and neural differentiation, 1 lacking differentiation with either cell type. The myoid tumors involved gastric fundus in 9/13 and 5/7 benign lesions and lesions with ...
2000-02-01
Energy Technology Data Exchange (ETDEWEB)
Seismic monitoring at the Las Tres Virgenes, BCS, geothermal field started in 1992 with an analog station of vertical components detecting a large number of earthquakes of varying magnitudes. In February 1993, a seismic network was installed, composed of six digital stations DR-2000-with S-6000 and S-5000 sensors and three registration channels (N-S, E-W and vertical). This was the basis for the development of a program to correct arrival-time data for P and S waves due to instrument drift. From January to April 1994 and May to August 1995, based on the 170 seismic events recorded, a velocity model was proposed. From December 1995 to July 1996, seismic data were processed and interpreted, and zones of occurrence were determined for events according to magnitude and the predominant noise in the field. From September 2003 to December 2004, 10 seismic stations (permanent and temporary) were installed and monitored and it was concluded the most active fault system was El Volcan. From ...
2009-07-15
Energy Technology Data Exchange (ETDEWEB)
Rectus sheath hematomas are a frequent but sometimes misdiagnosed disease in patients under anticoagulative drugs, hemodialysis, or simply in the elderly. The most frequent localization is in the lower part of the abdomen: the explanation lies in the anatomy of the abdominal wall, especially in the arcuate line of the rectus sheath. Aim of this work is to explain the reason of the almost constant location correlating the anatomy with the CT features. The rectus abdominis muscle lies between the aponeuroses of the transverse and oblique muscles which form the so called rectus sheath. This arrangement is found from the costal arch to a level approximately between the umbilicus and the pubic symphisis, where the rear layer of the rectus sheath ends with a curved edge, called the arcuate or semicircular line of Douglas. Beneath this line the aponeuroses of the three muscles pass in front of the rectus which is separated from the peritoneum only by the fascia trasversalis, a thin connective ...
2000-06-01
Energy Technology Data Exchange (ETDEWEB)
Purpose: Cardiomyopathy is one of the major complications of {beta} thalassaemia major as a result of transfusion iron overload. The aim of our study is to evaluate with MR if there is any difference of iron deposition signal intensity (SI) or distribution between non-cardiopatic and cardiopatic thalassaemic patients in order to establish if there is a relationship between cardiopathy and iron deposition. Materials and methods: We studied 20 patients affected by {beta} thalassaemia major, of whom 10 cardiopatic and 10 non-cardiopatic, and 10 healthy volunteers as control group. Serum ferritin and left ventricular ejection fraction were calculated in thalassaemic patients. All patients were examinated using a 1.5 MR unit with ECG-gated GE cine-MR T2*-weighted, SE T1-weighted and GE T2*-weighted sequences. In all cases, using an adequate ROI, the myocardial and skeletal muscle signal intensity (SI), the myocardial/skeletal muscle signal intensity radio (SIR) and the SI average of the ...
2005-02-01
Energy Technology Data Exchange (ETDEWEB)
The purpose of this paper is to report the personal experience with helical CT evaluation of hepatocellular carcinoma treated with various percutaneous interventional procedures. From December 1996 to September 1998 it were examined with helical CT 41 patients (73 nodules in all) with hepatocellular carcinoma treated with percutaneous ablation therapies: conventional ethanol injection in 18 subjects (31 nodules), one-shot ethanol injection 3 (8 nodules), radiofrequency thermal ablation in 16 (25 nodules), and combined chemo embolization and ethanol injection in 4 (9 nodules). CT performed was 4-27 days after the last session, acquiring biphasic volumetric images in 14 patients and triphasic volumetric images in 27. A second treatment with subsequent CT study was performed for 28 lesions; 15 underwent 3 serial studies and 6 underwent 4 studies. Compared with pretreatment findings, the diameter was unchanged in 62% of the nodules and increased in 38%. Morphology was unchanged in 63% of ...
1999-12-01
Energy Technology Data Exchange (ETDEWEB)
Penetrating liver wounds are related to many causes and rank second after blunt abdominal and liver trauma. In this report are examined the clinical and radiological findings of personal series of patients with penetrating trauma, especially by firearms and stab and cut wounds. It will also tried to define the diagnostic workup of these traumas, which is especially based on CT signs of liver damage and associated changes and which is of basic importance for following treatment, both surgical or conservative. In the last seven years it was retrospectively reviewed 31 cases of penetrating liver trauma. The patients were 19 men and 12 women, ranging in age 18 to 73 (mean 42), with penetrating liver injuries from firearms (16 patients) and stab (9 cases) wounds; 6 patients had injuries from different cases. Abdominal CT was carried out in emergency with the CT Angiography (CTA) technique in all patients. In the patients with suspected chest and abdomen involvement CT was performed from the ...
2000-12-01
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