... Future Job Fund Scheme Goodwood Allotments Location: Goodwood Allotments Work undertaken by long-term unemployed youngpeople under the Future Jobs Fund (FJF) transforms derelict allotments into a readily workable space for the local community. New Parks Skegness Ride Location: New Parks Youth Centre Youths from the New Parks Club for YoungPeople engage with sustainable transport and develop teamwork skills via a team bike ride. ...
Preventing tobacco use in youths may be an easier task than helping adults break the habit of smoking and overcome its ill effects. Using experimental procedures based on social work techniques,...Full Text Available
OBJECTIVE--To determine whether the seeming excess of childhood leukaemia and lymphoma identified in Seascale, Cumbria, UK, remains unusual when put into a wider context. DESIGN--Analysis of cancer...Full Text Available
BackgroundAs the promotion of alcohol and tobacco to youngpeople through direct advertising has become increasingly restricted, there has been greater interest in whether images...Full Text Available
Participation in conventional politics, such as elections, membership of organizations and political parties, is relatively low among young adults of ethnic minority background. Instead, engagement seems to find its way through aesthetic and other expressive channels of influence drawing on new technologies, impulses from transnational youth culture traditions, and both street riots and less conflictual actions. The aim of this article is to grasp a potential social movement in the making, by exploring the processes of articulation through which youngpeople from immigrant families in Norway express their political engagement. The phenomenon of articulation is understood as a process comprising three steps or modes: (i) becoming conscious; (ii) generating expressions and (iii) collective a...
The current research addressed age differences in internet use among Same Sex Attracted (SSA) individuals. In general, online communities are found to be a source of social support, especially for minority group members. However, it is unclear whether younger and older SSA people differ in their use of these communities. The present research examined age differences in use of online communities, hypothesizing that young SSA people primarily use these for social interaction and support, whereas older SSA people use online communities to seek sexual contacts. Study 1 examined age differences in motives to start using these websites. Study 2 examined age differences in use of online profiles and online social support. Results of both studies confirmed our hypotheses. Younger compared to older...
... Future Job Fund Scheme Goodwood Allotments Location: Goodwood Allotments Work undertaken by long-term unemployed youngpeople under the Future Jobs Fund (FJF) transforms derelict allotments into a readily workable space for the local community. Western Park Location: Western Park, Hinckley Road, Leicester Groundwork conservation officers and Future Jobs Fund staff renew a Western Park spinney making it a better place for all. Bhavyesh ...
Purpose Ultraviolet-B (UV-B) radiation can cause phototoxic macular injuries in youngpeople who have been sunbathing but not sungazing and in welders. Welders have a reportedly increased risk of uveal melanoma. We analyze phakic and pseudophakic risks for solar and welding arc UV-B exposure. Design Optical radiation measurement, analysis, and perspective. Methods Spectral transmittances were measured for UV-transmitting, UV-blocking, and blue-blocking intraocular lenses (IOLs). The photoprotective performances of crystalline and intraocular lenses were analyzed using relevant epidemiologic and laboratory data and action spectra for acute retinal phototoxicity and melanoma photocarcinogenesis. Results Crystalline lens UV-B retinal protection is deficient in children and young adults, incre...
The paper is devoted to analysis of Russian nuclear education system: its current status, specific features, difficulties and prospects. Russian higher education system in nuclear engineering has been created simultaneously with the development of nuclear industry, and the system completely satisfied all industrial demands for the specialists of different qualification levels. For the past several decades, nuclear education has lost its attractiveness to youngpeople. The paper discusses the actions to be undertaken for reversing the situation. The paper underlines particularly the special role of international collaboration and all-European integration of nuclear educational programmes for further development of nuclear education all over the world. (author)
While levels of weight bias vary among individuals, it is not clear why one person possesses stronger anti-fat attitudes than another person. This investigation examined whether individual differences commonly associated with greater anti-fat bias are also associated with a greater preference for thinness among people of varying levels of weight. Young adults (62% women; 84% Caucasian) recruited from psychology classes (N=308) rated four male and female figures with approximate BMIs of 18.5, 25, 30, and 40, on measures of dislike and personality characteristics and completed measures assessing weight controllability, attitudes toward the obese, and perceptual reliance. Greater negative attitudes, weight controllability beliefs, and perceptual reliance were positively associated with greater dislike and negative personality attributes among obese/severely obese figures, but inversely related among low normal weight figures. Individuals who judge ...
This article explores the extent to which and how non-formal education (NFE) contributes to the development of a more diversified basic education system and thus to the achievement of EFA. It outlines the current nature of NFE, the frameworks provided by the EFA movement, and the evolution of reflection, policies and practices in NFE in relation to basic education as a whole. Based on significant developments in various countries across the South, the article also discusses some key challenges that ministries of education and their partners need to face in moving towards relevant and equitable diversity in education. The article posits that, despite the many problems faced by NFE, there is justification for building on its experiences and integrating these within a larger policy and system...
Background:- Diagnoses of paediatric bipolar disorder have increased over the last two decades in the United States, where high levels of comorbidity with ADHD have also been reported. Aims:- To explore how British clinicians apply these diagnoses. Method:- We compared 378 youngpeople under the age of 18 who received a diagnosis of bipolar disorder and/or ADHD from a large NHS mental health trust between 1992 and 2007. Results:- Children with bipolar disorder were rare in this sample (n-=-35, 1.0%), particularly under the age of 13 (n-=-9, 0.3%). Children with bipolar disorder presented more often with affective and psychotic symptoms than children with ADHD. Irritability was common in both disorders. Core ADHD symptoms were prevalent in both conditions but occurred in a greater proportio...
Background Aluminium phosphide tablets popularly known, as ?celphos? is a highly toxic fumigant used as insecticide for preservation of food grains. India is an agricultural country and celphos tablets are easily available to psychologically vulnerable youngpeople. It is swallowed with suicidal intent and death comes in minutes. Patients and methods In this series there were seven patients with tracheo esophageal complications out of 342 patients reviewed. Four patients had esophageal stricture and three had stricture plus tracheo esophageal fistulas. Types of symptoms including progressive dyshagia and extent of respiratory symptoms were evaluated. Nutrition status and success or failure of dilatation at the time of endoscopy was taken into account. The criteria for oesophageal replaceme...
There was a total bus strike in the Danish town of Esbjerg during the spring of 1995. It lasted for a very long period of time and was extremely disruptive. After this the number of bus passengers fell dramatically. As a result, a group of researchers in this field, employed at Aalborg University initiated an investigation of how former bus passengers solved their personal transport problems without the help of a bus service. Telephone interviews were carried out and 1485 persons agreed to take part in the investigation. The data collected in this way are presented in the paper and give information on the number of people who owned cars, how often members of a family availed themselves of bus transport, age groups, the alternative means of transport used generally or for conveyance to the place of work or school, amount of extra, or less, travel time, travel expenses, and other irritations experienced in connection with the strike. It is concluded that the ...
In the future even more than in the past, nuclear power will be indispensable in the present industrialized countries and in those still under development. The safe, nonpolluting, and economic supply of energy to mankind in the future includes so many different problems that the technology of the high-temperature reactor at its present level of development, and with the possibilities is offers above and beyond those provided by other, established, technologies, does not have to mark the end of some old line of development, but rather should be seen as the starting point of a development offering promise for the future. It is for this very reason that the extensive, valuable knowledge and experience accumulated in the construction, operation, and decommissioning of the AVR and THTR plants, the development of the HTR module and other variants and, last, but not least, the valuable results of projects such as PNP, NFE, and HHT, must be preserved at the research ...
Throughout their history, Americans have believed that citizens' fulfillment of their individual duties in a participatory democracy is at least partly met through the forming of groups around important societal issues. Given the complex nature of political socialization, this study investigated identifiable determinants of social action that might be used to advantage in educating youngpeople for citizenship in a democracy. This study attempted to differentiate among junior high, high school and college students (N=517) who were inclined and not inclined to act on their concerns about nuclear threat with selected demographic, psychological, political, and educational variables. The results of a discriminant functional analysis indicated that in comparison with the non-action group, students in the action group were characterized by reporting less trust in government, more exposure to sources of nuclear war information, more political ...
Iron is an essential micronutrient. As an integral part of hemoglobin, it is essential for the transport of oxygen in blood to the tissues. It is an important component of cytochromes and other tissue enzymes that are critical for cellular respiration and of myoglobin that helps maintain oxygen reserve in the muscle. It is also involved in the normal functioning of the immune function, and in the synthesis of steroid hormones and bile acids. There are serious functional consequences to iron deficiency and iron deficiency anemia (IDA) in the human body. The deleterious effects include increased morbidity, preterm delivery, low birth weight, delayed cognitive development, lowered cellular immunity and reduced physical work capacity. However, iron deficiency and IDA remain the world's most common deficiency disease in the 21st century. Recent estimates of people affected with iron deficiency and IDA are 3.5 billion. Iron deficiency anemia is most prevalent and severe ...
Physiological functions are carried out by differentiated cells, with finite lifespans, which age and need to be replaced. In young individuals, tissue functions are sustained at optimal levels because cellular dysfunction and cell loss are balanced by the emergence of newly differentiated cells as stem cells and their partially differentiated descendants replicate. However, with the passage of time the mitotic rates of these cells diminish. Eventually, replications occur too infrequently to offset the loss. It is at this point that the tissue begins to show structural changes and declining function which, as they become pervasive, are identified as ageing. In this paper the theory is set forth that: (1) Diminishing mitotic activity in older tissues results from limited stem cell replicative capacity. (2) All stem cells, regardless of tissue, exhibit similar replicative patterns over time, progressing from the actively proliferating to the nonproliferating state. ...
Divided into three sections, this paper briefly presents Kohlberg's theory of moral reasoning; surveys some key research relating childrearing practices to adolescents' social competence, including moral reasoning; and reports research findings concerning the value systems adolescents develop. The first section characterizes preconventional, conventional, and postconventional morality and explores ways of promoting the development of a mature concept of justice, which includes role taking and living in a "just community." The second section focuses on aspects of social learning, which include authoritative parenting, inductive discipline, argumentative discourse, and tradition-based upbringing. In addition, this section explores socialization practices that hinder the development of mature moral reasoning. Focusing initially on characteristics of alienated youth and parental influences on such youth, the third section describes studies investigating the values development of New York ...
Website hosted by the American Ceramics Society with history of ceramics education, along with notable ceramic engineering educators. "In May 1894, two rooms in the basement of The Ohio State University?s College of Engineering were set aside to create a new department: Clay-Working and Ceramics. Founded with a $10,000 grant from the State of Ohio, the department was the first of its kind anywhere in the nation. The course of study was the idea and personal project of Edward Orton Jr., a young mining engineer. Orton had gathered his ceramic knowledge, piece by piece, from various jobs in coalmines, glass factories and steel plants. In 1893 he was the superintendent for a factory that made paving bricks. Orton?s factory, hit by an ?acute crisis,? closed, leaving him with some unexpected extra time. He used the opportunity to lobby for the passage of what some people dubbed the ?Mud Pie Bill? ? legislated funding to establish a school to train ...
AbstractA young, male miniature poodle was presented with severe neurological problems. Laboratory tests and ultrasonograph examination were consistent with extrahepatic portosystemic...Full Text Available
Copy number variants (CNVs) are an important component of genomic variation in humans and other mammals. Similar de novo deletions and duplications, or copy number changes (CNCs), are now known to be...Full Text Available
Variant alleles of the mannose binding lectin (MBL) gene are associated with increased susceptibility to infection and polymorphisms of tumour necrosis factor and lymphotoxin alpha genes (TNF, LTA)...Full Text Available
AbstractGenetic-variant analysis of rabies viruses provides the most sensitive epidemiologic tool for following the spread and persistence of these viruses in their wildlife hosts. Since...Full Text Available
BackgroundVariant Creutzfeldt–Jakob disease (vCJD) is a prion disease thought to be acquired by the consumption of prion-contaminated beef products. To date, over 200 cases...Full Text Available
The entire genome of rabies virus vaccine strain Flury-LEP-C, a Chinese variant of the rabies virus vaccine strain Flury-LEP, was sequenced. The overall length of the genome of Flury-LEP-C strain was...Full Text Available
Structural variants which cause changes in copy numbers constitute an important component of genomic variability. They account for 0.7% of genomic differences in two individual genomes, of which...Full Text Available
... United States, there are 14 million people with diabetes and while most will not lose their vision ... good deal higher among people with Type I diabetes -- the type that usually begins in childhood and ...
Background An increasing number of people have access to the Internet, and more people are seeking tobacco cessation resources online every year. Despite the...Full Text Available
By a variant version of Fountain Theorem due to Zou [W. Zou, Variant fountain theorems and their applications, Manuscripta Math. 104 (2001) 343-358], the existence of infinitely many solutions is obtained for a class of biharmonic equations where the nonlinearity involves a combination of superlinear and asymptotically linear terms.
The authors report an effort to determine the basis for the altered migration of seven inherited albumin variants detected by one-dimensional electrophoresis in population surveys involving tribal Amerindians and Japanese children. An amino acid substitution has thus far been determined for four of the variants. The randomness in the albumin polypeptide of these and the other sixteen independently ascertained amino acid substitutions of albumin and proalbumin thus far established was analyzed; the clustering of eight of these at two positions in the six-amino acid propeptide sequence seems noteworthy. By comparison with other proteins studied by electrophoresis, albumin exhibits average variability. It is a paradox that individuals who, for genetic reasons, lack albumin exhibit no obvious ill effects; yet, electrophoretic variants of albumin are no more numerous than are variants of proteins, the ...
Exposure to crystalline silica dust causes multiple diseases, but silicosis and silica dust-associated tuberculosis (TB), in particular, are the two diseases that remain high on the list of occupational health priorities in low-income countries and that still occur in some high-income countries. The prevalence of silica-related TB is exacerbated by the human immunodeficiency virus (HIV) epidemic in low-income countries. This review describes the morphology of silica and the variable potency of the different forms. Sources of crystalline silica are discussed, with emphasis on less commonly recognised sources, such as small-scale mining operations and agriculture. Trends in the prevalence of silicosis are also presented. Although efforts have been made for many years in most countries to reduce silica dust levels, silicosis continues to occur even in youngpeople. The clinical and pathological features and diagnosis of silicosis, with emphasis on ...
The crystallography of #alpha#(hcp) precipitates formed on the #beta#(bcc) matrix grain boundaries has been studied with transmission electron microscopy (TEM) in a Ti-15V-3Cr-3Sn-3Al alloy. The #alpha# precipitates have a near-Burgers orientation relationship with respect to at least one of the adjacent #beta# grains. Among the possible 12 variants in this orientation relationship, the variant that [11 bar 20]_#alpha# is parallel to the _#beta# closest to the grain boundary plane tends to be preferred by the #alpha# precipitates. Additionally, further variant selections are made so as to minimize the deviation of orientation relationship with respect to the ''opposite'' #beta# grain from the Burgers one. Such rules in variant selection often result in the formation of precipitates with a single variant at a planar grain boundary. Prior small deformation of #beta# matrix changes the ...
... Tauris, 2005. 'Inclusions/exclusions in rural space', in Cloke, P., Marsdan, T and Mooney, P, eds, Handbook of Rural Studies, Sage, 2006, 401-410 people/dsibley/publications.html CURRICULUM VITAE people/dsibley/cv.html PRESENTATIONS people/dsibley/presentations.html TEACHING people/dsibley/teaching.html Homepage | Contacts | Site Map | Privacy Statement | Webmaster | Faculty of Environment | University of Leeds | Campusweb School of Geography, University of Leeds, Leeds LS2 9JT,...
This research focuses on young Mexican American girls who are not formal gang members yet participate in street-based activities of male gangs and engage in risk behaviors. These females comprise...Full Text Available
This study sought to assess the association between traditional masculine gender role ideologies and sexual risk and intimate partner violence (IPV) perpetration behaviors in young men's heterosexual...Full Text Available
... the nest with young when the female left (male meadow voles were in the nest with young too infrequently ... prairie voles, whereas the number of checks that male meadow voles were in the nest increased s...
Though the genetic background of ischaemic and haemorrhagic stroke is often polygenetic or multifactorial, it can in some cases result from a monogenic disease, particularly in young adults. Besides...Full Text Available
Are economic resources related to relationship quality among young couples, and to what extent does this vary by relationship type? To answer these questions, we estimated regression models...Full Text Available
A review is made of some recent developments in the application of the Bohr Hamiltonian to transitional nulcei. The primary concern is to understand the advantages and limitations inherent to the basic model and its many variants. (author).
BackgroundEmphysematous cholecystitis is a variant of acute cholecystitis which is generally caused by gas-forming organisms. Emphysematous cholecystitis may cause gas spreading...Full Text Available
... which may have embedded remote terminals, and (4 ... model the time-variant or stochastic aspects of ... on such system parameters as queue size, time ...
We investigated activity patterns of 17 elementary school students aged 10-12, and 19 high school students aged 13-17, in suburban Los Angeles during the oxidant pollution season. Individuals' relationships between ventilation rate (VR) and heart rate (HR) were calibrated' in supervised outdoor walking/jogging. Log VR was consistently proportional to HR; although calibrations' were limited by a restricted range of exercise, and possibly by artifact due to mouthpiece breathing, which may cause overestimation of VR at rest. Each subject then recorded activities in diaries, and recorded HR once per minute by wearing Heart Watches, over 3 days (Saturday-Monday). For each activity the subject estimated a breathing rate--slow (slow walking), medium (fast walking), or fast (running). VR ranges for each breathing rate and activity type were estimated from HR recordings. High-school students' diaries showed their aggregate distribution of waking hours as 68% ...
BackgroundThis study focuses on the role of an Internet-based group for people who have an autoimmune liver disease, primary biliary cirrhosis. Primary biliary...Full Text Available
ObjectivesTo examine whether people who expect to live longer engage in healthier behaviors relative to people who expect to live shorter lives.Full Text Available
Background:No recent data exist on human papillomavirus (HPV) infection in Beijing, People's Republic of China.Materials and methodWe interviewed...Full Text Available
The purpose of this study was to assess the effect of a 735-kV transmission line on the electric and magnetic field exposures of people living at the edge of the line's right of way. Exposure of 18...Full Text Available
BackgroundSocial isolation affects a significant proportion of older people and is associated with poor health outcomes. The current evidence base regarding the effectiveness of...Full Text Available
Objectives1. To identify with older people the problems which they encounter in finding their way about public building/spaces.~%~2. To produce ideas, in consultation with older people, for an information/navigation aid that might facilitate their use and enjoyment of public buildings/spaces, notably hospitals, large shops, railway stations, airports.~%~3. To develop an emulation model of the information/navigation aid~%~4. To monitor use of the model by older people~%~5. To identify further research~%~6. [continued...]DescriptionThe growth in the number of older people offers scope for the development of customised information/navigation aids to help them to find their way around complex public spaces. New technology however is unlikely to be taken up by older people unless it is acceptable to them. The research will involve engineers in designing, testing and modifying a model of ...
... Such disorders include depression , anxiety disorders , bipolar disorder , attention deficit hyperactivity disorder (ADHD) , and many others. Some people who develop ...
The ?new variant famine? hypothesis posits links between HIV/AIDS and new patterns of impoverishment, food insecurity and hunger, in southern and eastern Africa. This paper explores the relevance of the NVF hypothesis to understanding Swaziland?s recurrent food crises and high HIV prevalence. Evidence exists that all four markers of NVF are present in Swaziland. The national government and the international community will have to contend with this phenomenon in future planning for the wellbeing of Swazi citizens.
A single Klebsiella pneumoniae strain isolated in a Bulgarian hospital was found to produce CTX-M-71, a new CTX-M variant characterized by one amino acid substitution...Full Text Available
Recent GWAS studies focused on uncovering novel genetic loci related to AD have revealed associations with variants near CLU, CR1, PICALM and BIN1....Full Text Available
Surveys of the antigenic properties of a wide range of variants of the H3N2 (Hong Kong) influenza virus subtype have revealed complex patterns of variants cocirculating during each of the main epidemic...Full Text Available
Genome-wide association studies (GWAS) have established a variant, rs10993994, on chromosome 10q11 as being associated with prostate cancer risk. Since the variant is located outside of a protein-coding...Full Text Available
The microstructural development inside the stress induced martensite (SIM) variants in Ti-Ni-Nb alloy with various degrees of deformation have been revealed by electron microscopic observations. The orientation relationship between the SIM and the parent phase has been found: [1{bar 1}0]{sub M}{parallel}[11{bar 1}]{sub B2}, (001){sub M} 5{degree} away from (101){sub B2}. The lattice invariant shear of the SIM variants at the slightly deformed stage is dominantly (11{bar 1}) Type I twin. Besides the ordinary slip, the adjustment and development of the internal secondary twinning from (11{bar 1}) Type I twin to {l_angle}011{r_angle} Type II/ or (011) Type I twin, (001)compound twin and (111) Type I twin happen concurrently or in combination inside the SIM variants with the further deformation. The corresponding deformation mechanisms include stress induced reorientation of SIM substructural bands by the most favorably ...
In the future even more than in the past, nuclear power will be indispensable in the present industrialized countries and in those still under development. The safe, nonpolluting, and economic supply of energy to mankind in the future includes so many different problems that the technology of the high-temperature reactor at its present level of development, and with the possibilities is offers above and beyond those provided by other, established, technologies, does not have to mark the end of some old line of development, but rather should be seen as the starting point of a development offering promise for the future. It is for this very reason that the extensive, valuable knowledge and experience accumulated in the construction, operation, and decommissioning of the AVR and THTR plants, the development of the HTR module and other variants and, last, but not least, the valuable results of projects such as PNP, NFE, and HHT, must be preserved at the research ...
Studies have indicated that many people misunderstand climate change. Equipped with a limited mental model they inappropriately use a pattern matching heuristics to analyze climate change and mistakenly believe that we can stabilize atmospheric CO2 by keeping anthropogenic emissions at current rates. Drawing on the findings from cognitive and developmental psychology, I argue that the widespread misunderstanding of climate change may arise from an error in people?s ontological assumptions. The pattern matching heuristics highlights correlations in shape and associates with a static mental model, both of which are effective for understanding objects. When people adopt the pattern matching heuristics, they may have implicitly treated climate change as an object. However, climate change belon...
A mechanical model with local resonators is proposed as an acoustic metamaterial that exhibits an unusual frequency-dependent effective stiffness. If treated as an equivalent elastic solid, its effective Young's modulus can become unbounded or vanishingly small at two respective frequencies. Moreover, in a certain frequency range, the effective Young's modulus would become negative, resulting in a band gap that coincides with this frequency range. The wave attenuation behavior and mechanism are studied through numerical simulations on the acoustic metamaterial model. The capability of the metamaterial to selectively block or filter unwanted waves is demonstrated by a numerical simulation example.
Abstract Copy number variants (CNVs) are known to be associated with complex neuropsychiatric disorders (e.g., schizophrenia and autism) but have not been explored in the isolated features of aggressive behaviors such as intermittent explosive disorder (IED). IED is characterized by recurrent episodes of aggression in which individuals act impulsively and grossly out of proportion from the involved stressors. Previous studies have identified genetic variants in the serotonergic pathway that play a role in susceptibility to this behavior, but additional contributors have not been identified. Therefore, to further delineate possible genetic influences, we investigated CNVs in individuals diagnosed with IED and/or personality disorder (PD). We carried out array comparative genomic hybridizati...
The study of quantum walk process has been widely divided into the two standard variants, the discrete-time quantum walk (DTQW) and the continuous-time quantum walk (CTQW). The connection between the two variants has been established by considering limiting value of the coin operation parameter in the DTQW and the coin degree of freedom is show to be unnecessary [26]. But the coin degree of freedom is an additional resource which can be exploited to control the dynamics of the QW process. In this paper we present a generic quantum walk (QW) model using a quantum coin-embedded unitary shift operation U_{C}. The standard version of the DTQW and the CTQW can be conveniently retrieved from this generic model retaining the features of the coin degree of freedom in both the variants.
A diagnosis of dementia is devastating at any age but diagnosis in younger patients presents a particular challenge. The differential diagnosis is broad as late presentation of metabolic disease...Full Text Available
For some neurotoxic chemicals, neurobehavioral effects are now considered to be among the most sensitive end points yet detected, particularly if exposures occur during critical windows of vulnerability....Full Text Available
The present study investigated the association of mothers’ marriage and changes in young adolescents’ cognitive and socioemotional development and changes in family processes....Full Text Available
BackgroundThe National Cancer Institute has concluded that exposure to smoking in movies causes adolescent smoking and there are similar results for young adults.Full Text Available
Two experiments are reported on the influence of cognitive aging on grammatical choice in language production. In both experiments, participants from two age-groups (young and old) produced...Full Text Available
The Ty transposable elements of Saccharomyces cerevisiae form a heterogeneous family within which two broad structural classes (I and II) exist. The two classes differ by two large substitutions and...Full Text Available
To evaluate the role of chronic inflammation in the development of gallstones and biliary tract cancer, we examined the risk associated with 62 single nucleotide polymorphisms (SNPs), including...Full Text Available
The hemagglutinin (HA) glycoprotein of influenza virus performs two critical roles during infection: it binds virus to cell surface sialic acids, and under mildly acidic conditions it induces fusion...Full Text Available
HIV-1 nonsubtype B variants account for the majority of HIV infections worldwide. Drug resistance in individuals who have never undergone antiretroviral therapy can lead to early failure and...Full Text Available
The influence of high temperature thermal ageing treatments on the development of intercrystalline creep damage in two variants of Alloy 800 has been investigated. Ageing up to 3000 h and creep testing were carried out at 800 and 900 C. The high temperature behaviour of the 800HT variant is discussed with reference to the effect of heat treatments on the microstructure. The metallographic methods by which the creep damage was quantitatively determined are described. The growth rate of intercrystalline microcracks was described using a statistical model and the dependence of crack growth rate on the thermal history for both 800HT and 800H was determined. The carbide precipitation and growth processes were determined as functions of the exposure temperature and duration. The results showed the three characteristic stages, precipitation, growth and coarsening (Ostwald ripening). The largest increase in the intergranular creep damage was found in ...
BackgroundEpidemiological studies have shown a J- or U-shaped relation between alcohol and type 2 diabetes and coronary heart disease (CHD). The underlying mechanisms are not clear....Full Text Available
Photosynthetic (Ps) electron transport pathways often contain multiple electron carriers with overlapping functions. Here we focus on two c-type cytochromes (cyt) in facultative phototrophic...Full Text Available
PurposeIt has been demonstrated that mutations in deafness, autosomal recessive 31 (DFNB31), the gene encoding whirlin, is responsible for nonsyndromic hearing loss...Full Text Available
The properties of an atypical Brucella strain isolated from lymph node tissue of a cow slaughtered as a brucellosis reactor were examined. The organism was Gram negative and highly pleomorphic, existing...Full Text Available
Objectives:Copy number variants (CNVs) have been recognized as a source of genetic variation that contributes to disease phenotypes. Alzheimer disease (AD) has high heritability...Full Text Available
In a follow-up to our previously reported genome-wide association study of cutaneous basal cell carcinoma (BCC)1, we describe here several new susceptibility...Full Text Available
BackgroundIndividuals living in malaria endemic areas generally harbour multiple parasite strains. Multiplicity of infection (MOI) can be an indicator of immune status. However,...Full Text Available
PurposeThe size of neuronal populations is modulated by gene variants that influence cell production and survival, in turn influencing neuronal connectivity, function,...Full Text Available
Dyslexia (or reading disability) and specific language impairment (or SLI) are common childhood disorders that show considerable co-morbidity and diagnostic overlaps and have been suggested to share...Full Text Available
Human erythrocyte glucose-6-phosphate is normally quite stable in the presence of 10 #mu#M NADP"+. Certain glucose-6-phosphate dehydrogenase variants lose virtually all their activity at this concentration of NADP"+ but are reactivated by 200 #mu#M NADP"+. Such variants presumably have a defect in their NADP"+-binding site. The authors analyzed the sequence of cDNA or genomic DNA from seven unrelated patients with hemolytic anemia due to the inheritance of variants that are reactivated by NADP"+. Six patients had substitutions of one of three adjacent amino acids, and the seventh patient had another amino acid substitution 23 residues downstream. These amino acids are highly conserved, all being present in rat and all but one being found also in Drosophila. The anomalous electrophoretic behavior of some of the variants can be explained by their loss of ability to bind NADP"+. The conclude that the ...
Tamoxifen (TAM) is a selective estrogen receptor modulator widely used in the prevention and treatment of breast cancer. A major mode of metabolism of the major active metabolites of TAM, 4-OH-TAM...Full Text Available
Pseudoaneurysms related to the superior mesenteric artery (SMA) are a recognised complication of trauma to the vessel, and successful treatment with stenting has been previously described. We report...Full Text Available
BackgroundMicroorganisms display vast diversity, and each one has its own set of genes, cell components and metabolic reactions. To assess their huge unexploited metabolic potential...Full Text Available
Dedifferentiated liposarcoma (DDLPS) is a variant of liposarcoma but with a more aggressive course. It occurs most commonly in the retroperitoneum and rarely in any other anatomical location. We describe...Full Text Available
Phosphorus is an essential mineral that maintains cellular energy and mineralizes the skeleton. Because complex actions of ion transporters and regulatory hormones regulate serum phosphorus concentrations,...Full Text Available
The complete nucleotide sequences of two alleles of cellobiose dehydrogenase, cdh-1 (3,627 bp) and cdh-2 (3,623 bp), from Phanerochaete chrysosporium OGC101 are reported. The nucleotide sequences of...Full Text Available
The amyloidoses are the prototype gain of toxic function protein misfolding diseases. As such, several naturally occurring animal models and their inducible variants provided some of the first...Full Text Available
BackgroundBlue nevi that arise from the Müllerian tract are rare melanocytic lesions. Several histopathologic variants of cellular blue nevi have been described. The angiomatoid...Full Text Available
A hitherto unrecognized variant of solid-pseudopapillary tumor (SPT) of the pancreas is reported. The tumor presented in the pancreatic tail of a 44-year-old female patient. It was a well-defined, solid...Full Text Available
A comparative study has been carried out of the growth of two lines of Datura innoxia (Mill.) cells, designated DI-6 and NR1, their resistance to chlorate, and their ability to assimilate...Full Text Available
Schizophrenia and bipolar disorder are leading causes of morbidity across all populations, with heritability estimates of ∼80% indicating a substantial genetic component. Population genetics...Full Text Available
Summary The First Nations people of British Columbia experience reincarnation as a revitalization of their culture. This article documents the perseverance of reincarnation experiences among the Beaver, Witsuwit'en, and Gitxsan peoples of British Columbia, as well as my own growth in understanding such experiences. It recounts examples of rebirth cases. It explains what rebirth experiences mean to the First Nations people. It describes how these experiences are embedded in their perception of this world and embodied in their beliefs of spiritual realms, which include the interconnected and parallel worlds of fish and land animals, on this world and in spiritual dimensions. While the rebirth worldview contrasts with that of the Western scientific world, this is a worldview I have come to en...
A plethora of experimental studies use mtDNA as a marker of demographic processes without questioning the possibility that selection may bias their interpretations. We studied four lines of Drosophila melanogaster that have a standardized nuclear DNA but variable mtDNA. We completed the sequencing of the mitochondrial genomes (excluding the A+T rich region) and compiled the differences. We then assayed male influence on oviposition, starvation resistance, lipid proportion and physical activity. We discuss these results in terms of the known differences between the lines and conclude that naturally occurring mtDNA variants in D. melanogaster are expressed at the level of the organismal phenotype. PMID:21757031
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INTRODUCTIONSexual dysfunction symptoms in patients with HIV have not been fully investigated in Brazil.OBJECTIVESTo investigate the association...Full Text Available
BackgroundA large and increasing part of the European population has a history of migration. Germany, for example, is home to about 15 million people with migrant background, which...Full Text Available
PurposeTo describe the prevalence of cataract in older people in 2 areas of north and south India.DesignPopulation-based, cross-sectional study.ParticipantsRandomly...Full Text Available
The geographical arrangement of people on the surface of the earth is approximated by a mathematical equation of 361 terms. This is a convenient form for comparison with other distributions and for...Full Text Available
ObjectiveTo investigate the prevalence of complicating and concurrent morbidities in older diabetic patients and to evaluate to what extent their occurrence affects the burden of...Full Text Available
BackgroundMalaria is one of the most important tropical diseases that affects people globally. The influence of environmental conditions in the patterns of temporal distribution...Full Text Available
... elevated blood sugar levels, but not full-blown diabetes. What are the keys to preventing the disease? ... been well studied, in a study called The Diabetes Prevention Program, in several thousand people with this ...
This is a presentation on Human Factors in reactor operations. It discusses issues that deal with power plant operations, training and design, operational effectiveness and safety, supporting people to achieve effective and error free performance.
X-Plain Heart Valve Replacement Reference Summary Introduction Sometimes people have serious problems with their heart valves. A heart valve repair or ...
People assess the quality of the air indoors primarily on the basis of its odors and on their perception of associated health risk. The major current contributors to indoor odorants are human occupant...Full Text Available
to Cool Spots Hanford Fun Facts Classroom Projects Famous People of Hanford Counterintelligence Home Employee Responsibilities CI Information CI Resources Points of Contact...
Background:People with severe and persistent mental illness need help in most aspects of their lives, as the disability associated with these diseases can be debilitating....Full Text Available
Abstract In many places in the world the effects of common floods are increased by climate change. In the area around the Indonesian city of Semarang, the number and effects of tidal flooding are becoming more and more severe. We found that the inhabitants used different strategies against the impact of flooding. In both the existing and the predicted flood prone areas, most people appear not to intend to leave the area, even when the floods become everyday routine. People are connected to their dwellings in a way that abandoning is not a realistic scenario. This study provides relevant information about the way people in the affected areas perceive flood risks and adaptation opportunities. Governmental policy-makers and urban planners could base their strategies and actions on this inform...
When casein, a milk protein, is hydrolyzed, it renders human foods that contain it (e.g., hypoallergenic infant formula, cheeses) distasteful to many people. This rejection...Full Text Available
Schizophrenia and bipolar disorder share genetic risk, brain vulnerability, and clinical symptoms. The ZNF804A risk variant, rs1344706, confers susceptibility for both disorders. This study aimed to identify neural mechanisms common to both schizophrenia and bipolar disorder through this variant's potential effects on cortical thickness, white matter tract integrity, and cognitive function. Imaging, genetics, and cognitive measures were ascertained in 62 healthy adults aged between 18 and 59 years. High-resolution multimodal MRI/DTI imaging was used to measure cortical thickness and major frontotemporal and interhemispheric white matter tracts. The general linear model was used to examine the influence of the ZNF804A rs1344706 risk variant on cortical thickness, white matter tract integrity, and cognitive measures. Individuals homozygous for the risk variant ('A' allele) demonstrated reduced cortical ...
The paper brings forth the information related to the youth organizations acting at the factory, their policies, provisions of youth incentives, intake of employees to the company, labor motivation. There is also the information on the events, which take place on site, on the arrangements of the young employees' leisure, as well as on the creative and productive potential of the factory. (author)
Background: Little is known about the effectiveness of behavioral strategies to prevent long-term weight gain among adolescents and young adults.Objective: The objective...Full Text Available
This paper presents new images and spectroscopy of NGC 34 (Mrk 938) obtained with the du Pont 2.5-m and Baade 6.5-m telescopes at Las Campanas, plus photometry of an HST archival V image. This Mv = -21.6 galaxy has often been classified as a Seyfert 2, yet recently published infrared spectra suggest a dominant central starburst. We find that the galaxy features a single nucleus, a main spheroid containing a blue central disk, and tidal tails indicative of two former disk galaxies. These galaxies appear to have completed merging. The remnant shows three clear optical signs that the merger was gas-rich ("wet") and accompanied by a starburst: (1) It sports a rich system of young star clusters, of which 87 have absolute magnitudes -10.0 > Mv > -15.4. Five clusters with available spectra have ages in the range 0.1-1.0 Gyr, photometric masses between 2x10^6 and 2x10^7 Msun, and are gravitationally bound young globulars. (2) The blue central ...
BackgroundMany emergency ambulance calls are for older people who have fallen. As half of them are left at home, a community-based response may often be more appropriate than hospital...Full Text Available
ObjectivesObjectives Not AvailableDescriptionOne significant research challenge posed by the growing number of older people in the population concerns the mobility-related problems which increase with age, inhibit independence, and can be a prime cause of admission to expensive institutional settings. The scope for engineering advances, particularly in the field of rehabilitation and assistive technology, is immense. The challenge is to produce aids, devices and products that are attractive to older people themselves, since without such [continued...
...Keeping chickens: a beginner's guide : Directgov - Environment and greener living chickens, feeding chickens, egg marking, registering a ...flock, battery hens Chickens; Department for Environment, Food and Rural Affairs; Registrations; Animals; Livestock; Local government; Local ...authorities A guide for people keeping chickens on the laws for registering and feeding them, and how to spot key diseases. A ...guide for people keeping chickens on the laws for registering and feeding them, and how to spot key diseases. Keeping chickens: ...
... Bob, who also teaches the Computer Networks and Security course in the Department, has some concerns when it comes to these large monolithic social-networking sites, such as Facebook and MySpace . He would prefer to see people using a more distributed (or federated) approach to avoid single sites being able to gather lots of personal information, including relationships between people . However, most ...
China and CERN renew co-operation agreement for a further five years. During a visit to CERN on 17 February, Liu Yanhua, the vice-minister of science and technology of the People's Republic of China, signed a new co-operation agreement with the laboratory.
...sector in the Mediterranean, that should have been the pearl of the exhibition, there were never more than 25 people, with significant missing participants such the Mediterranean Institute for Certification IMC, the pioneers in exporting the Italian organic model throughout the Mediterranean region: due credit should have been given to them. Nah, they were not even invited.However, there were people that believed in this Sana, and committed themselves ...
Abstract Aim- According to the revised Bethesda Guidelines, colorectal cancer (CRC) occurring under age 50-years should be screened to exclude Lynch syndrome. However, in current practice in East Anglia, tumour screening is initiated only after genetics referral, reserved for those with a strong pedigree. This study aimed to determine how many patients with young-onset CRC undergo tumour screening in hospitals in East Anglia. Method- A retrospective case notes review over 5-years in four hospitals was undertaken to determine what proportion of those with young-onset CRC underwent referral for tumour screening and to assess local practices in terms of patient counselling and management. Results- One hundred and twenty-two patients were included. There was an average yearly caseload of 6-9 p...
The present study consisted of two experiments to compare new word learning in healthy young (N = 11) and older (N = 17) adults within an explicit learning paradigm. Experiment 1 investigated the new name learning for familiar objects, while Experiment 2 investigated learning names and descriptions for unfamiliar objects. Participants attended five learning sessions over 5 consecutive days, during which they viewed objects with novel names with/without descriptions. The older adults were as accurate as the young adults when recalling and recognizing new names during the learning sessions. With respect to response times, the older adults were as rapid as the young adults at recognizing the new names for the familiar objects, but were slower during the follow-up sessions. The older adults we...
Nitric oxide (NO) is a gas produced through the action of nitric oxide synthase that acts as a neurotransmitter in the central nervous system (CNS) of adult gastropod mollusks. There are no known reports of the presence of NOS-containing neurons and glial cells in young and adult Megalobulimus abbreviatus. Therefore, NADPH-d histochemistry was employed to map the nitrergic distribution in the CNS of young and adult snails in an attempt to identify any transient enzymatic activity in the developing CNS. Reaction was observed in neurons and fibers in all CNS ganglia of both age groups, but in the pedal and cerebral ganglia, positive neurons were more intense than in other ganglia, forming clusters symmetrically located in both paired ganglia. However, neuronal NADPH-d activity in the mesocer...
In experiments designed to detect new mutations affecting hemoglobin, we irradiated the male or female parent in reciprocal crosses of two mouse strains that differ in alleles at the hemoglobin (Hba, Hbb) loci as well as at five other specific loci. Offspring were analyzed for hemoglobin properties (electrophoretic pattern, solubility, crystal pattern), serum albumin differences, erythrocyte lysis, reticulocyte count, and external appearance. Five hemoglobin variants were found among the mutants. In three, the genetic contribution from the irradiated father was not expressed with regard to the #alpha#-chain; one carried a tandem duplication (the first known case in the mouse) involving Hbb; and one probably resulted from double nondisjunction of chromosome 7. The finding that major chromosome aberratios can mimic hemoglobin mutations indicates the need, in similar experiments, to follow F_1 screening with thorough cytogenetic analysis. The ...
BackgroundModern metal-on-metal hip resurfacing implants are being increasingly used for young and active patients, although the long-term outcome and failure mechanisms of these...Full Text Available
Presented here is a case of a young woman, with an undiagnosed osteoid osteoma of the spine, which presented with painful scoliosis in adolescence and was treated by bracing until her accession to adulthood....Full Text Available
AbstractThe structural integrity of striated muscle is determined by extra-sarcomere cytoskeleton that includes structures that connect the Z-disks and M-bands of a sarcomere to sarcomeres...Full Text Available
Disposable nappies (diapers) have been satisfactorily demineralized and used for the collection of excreta from infants and young children during mineral and trace metal balances. It was possible to...Full Text Available
PurposeDutasteride and finasteride are 5α-reductase inhibitors that dramatically decrease serum levels of dihydrotestosterone. Because androgens...Full Text Available
Aging is a risk factor for heart failure, which is a leading cause of death world-wide. Elderly patients are more likely than young patients to experience a myocardial infarction (MI) and are...Full Text Available
BackgroundYersinia pestis, the agent of plague, is a young and highly monomorphic species. Three biovars, each one thought to be associated with the last three Y....Full Text Available
Background. For unknown reasons, the prevalence of thyroid autoimmune disorders is higher in patients with Down's syndrome than in the general population. The present case strongly...Full Text Available
Testes of jellyfish Phialidium gregarium were fixed in 2 per cent OsO4 in Veronal-acetate buffer at pH 7.4. Thin sections showed that in young spermatids the spindle fibers...Full Text Available
BackgroundDespite the grave consequences of sexual violence, and it's persistence both within and outside marriages, this subject has received relatively little attention from researchers,...Full Text Available
BackgroundIndia experienced a rapid economic boom between 1991 and 2007. However, this economic growth has not translated into improved nutritional status among young Indian children....Full Text Available
Objective:This article examines relationships between reproductive onset and lifetime history of smoking, regular smoking, and nicotine dependence, and cannabis and other illicit...Full Text Available
BackgroundSeverely disabling chronic pain in the adult population is strongly associated with a range of negative health consequences for individuals and high health care costs,...Full Text Available
This review presents a summary of existing knowledge regarding the impact of testicular cancer along four broad domains, including romantic and sexual relationships, body image, and fertility....Full Text Available
Sexual pressure among young urban women represents adherence to gender stereotypical expectations to engage in sex. Revision of the original 5-factor Sexual Pressure Scale was undertaken in...Full Text Available
Recovery of hydraulic conductivity after the induction of embolisms was studied in woody stems of laurel (Laurus nobilis). Previous experiments confirming the recovery of hydraulic...Full Text Available
Sensory neurons in aging mammals undergo changes in anatomy, physiology and gene expression that correlate with reduced sensory perception. In this study we compared young and aged mice to identify...Full Text Available
Earlier studies of white London busmen revealed that the ischaemic heart disease experience of conductors is better than that of drivers. Various factors which might be related to this difference have...Full Text Available
Studies fail to find uniform effects of age-related or induced hypogonadism on human sexual function. We examined the effects of induced hypogonadism on sexual function in healthy men and women...Full Text Available
Young men's errors in sexual perception have been linked to sexual coercion. The current investigation sought to explicate the perceptual and decisional sources of these social perception errors,...Full Text Available
Background and purpose:The chicken anterior mesenteric artery contains an outer longitudinal smooth muscle layer, whose neural regulation remains to be elucidated. ATP evokes a depolarization...Full Text Available
We present photoelectric BVRI photometry for 16 T Tau and related stars in the Rho Oph dark cloud, as well as vidicon spectroscopic observations for nine stars. The color excesses of these stars favor circumstellar dust shells as the source of the observed infrared excesses.
Copper deficiency lowers brain copper and iron during development. The reduced iron content could be due to hypoferremia. Experiments were conducted to evaluate plasma iron and “ferroxidase”...Full Text Available
This case report describes the second known instance of a multifocal capillary pancreatic neoplasm. Both cases occurred in young African American females. A less-than-total pancreatectomy was performed...Full Text Available
The goal of this study was to determine if the exaggerated morphine-induced conditioned place preference (CPP) response seen in adult rats after preweanling methylphenidate exposure is unique...Full Text Available
Friends and colleagues remember John N. Brady, Ph.D., Chief of the Virus Tumor Biology Section of the Laboratory of Cellular Oncology, who died much too young at the age of 57 on April 27, 2009 of colon...Full Text Available
Endovascular treatment of post-traumatic pseudoaneurysms has become a viable, less invasive option when compared to open repair. Due to the relative youth of this technology, studies have yet to be...Full Text Available
This study investigated the impact of lifelong sedentariness on skeletal muscle mass and mitochondrial function. Thirty C57BL/6 strain mice (2 months) were randomly divided into three groups (young-Y;...Full Text Available
Background:Increasing evidence shows the importance of young age, estrogen receptor (ER), progesterone receptor (PR) status, and HER-2 expression in patients with breast cancers.Patients...Full Text Available
Sep 1, 2011 ... Title: Hardness, density, and shrinkage characteristics of silk-oak from Hawaii. Author: Youngs, R. L.. Date: 1964. Source: Research note FPL ...
Increasing numbers of human cowpox virus infections that are being observed and that particularly affect young non-vaccinated persons have renewed interest in this zoonotic disease. Usually causing...Full Text Available
The discovery that aerobic exercise increases adult hippocampal neurogenesis and can enhance cognitive performance holds promise as a model for regenerative medicine. This study adds two new...Full Text Available
1. One hundred and thirty-two antidromically identified paraventricular (PV) and supraoptic (SO) neurones were studied during milk ejection evoked by the suckling of the young, in thirty-four lactating...Full Text Available
Ewing's sarcoma is the second most common malignant bone tumor in children and young adults. It is most prevalent between the ages of 10 and 15 years. There are present two cases of Ewing's sarcoma of the chest wall. The clinical, radiological and pathological features are described and the therapeutic options are discussed. (Author)
In Staphylococcus aureus, a pronounced shift in position of the acriflavin resistance locus was observed when gene order was determined by marker frequency analysis of cells of various ages. In young cells (2-hour culture), acriflavin resistance was mappe...
BackgroundThe increasing prevalence of obesity in young women is a major public health concern. Few data are available concerning the epidemiology of malnutrition especially obesity...Full Text Available
The electrical parameters that affect young seedling growth were investigated. Voltages ranging from 5 to 40 volts were applied longitudinally along the mesocotyl region of 4-day old Zea mays...Full Text Available
ObjectivesWe examined the expression of Rho Kinase (ROK) isoforms in young and old rabbit’s detrusor smooth muscles (SM) during the progression of short term...Full Text Available
Most Vega-like stars have far-infrared excess (60micron or longward in IRAS, ISO, or Spitzer MIPS bands) and contain cold dust (~ 4% of the stars in nearby young stellar associations.
BackgroundWebsites of many rogue sellers of medications are accessible through links in email spam messages or via web search engines. This study examined...Full Text Available
Ewing sarcoma (ES) is the second most common type of primary bone malignancy in children and young adults. Survival rates for localized ES have improved to upwards of 70% with aggressive chemotherapy...Full Text Available
Ewing's sarcoma is the second most common bone malignancy affecting children and young adults. The prognosis is especially poor in metastatic or relapsed disease. The cell of origin remains elusive,...Full Text Available
Schwannomas are rare mesenchymal tumors of the gastrointestinal tract. Occurrence of these tumors is more common in the stomach than in the large intestine. These tumors usually present as polypoidal...Full Text Available
Sep 28, 2011 ... Description: Four Populus clones were grown in central Missouri for 2 years at 1 x 1 m spacing to study total biomass production on floodplain ...
Bhanja virus (BHAV) is pathogenic for young domestic ruminants and also for humans, causing fever and affections of the central nervous system. This generally neglected arbovirus of the family Bunyaviridae...Full Text Available
BackgroundIn Germany, there is a shortage of young physicians in several specialties, the situation of general practitioners (GP) being especially precarious. The factors influencing...Full Text Available
BackgroundPrevious research has demonstrated that exposure to images depicting the thin female ideal has negative effects on some females' levels of body dissatisfaction. Much of...Full Text Available
Solid-pseudopapillary tumor (SPT) is a rare neoplasm of the pancreas that usually occurs in young females. It is generally considered a low-grade malignant tumor that can remain asymptomatic for several...Full Text Available
Neurons are born throughout adulthood in the hippocampus and show enhanced plasticity compared to mature neurons. However, there are conflicting reports on whether or not young neurons contribute...Full Text Available
BackgroundWith rates of childhood obesity increasing, physical activity (PA) promotion especially in young children has assumed greater importance. Given the limited effectiveness...Full Text Available
How do people understand questions about cause and prevent? Some theories propose that people affirm that A causes B if A's occurrence makes a difference to B's occurrence in one way or another. Other theories propose that A causes B if some quantity or symbol gets passed in some way from A to B. The aim of our studies is to compare these theories' ability to explain judgements of causation and prevention. We describe six experiments that compare judgements for causal paths that involve a mechanism, i.e. a continuous process of transmission or exchange from cause to effect, against paths that involve no mechanism yet a change in the cause nevertheless brings about a change in the effect. Our results show that people prefer to attribute cause when a mechanism links cause to effect. In contr...
Abstract People with a physical disability are a population who for a number of reasons may be vulnerable to social isolation. Research into Internet based support sites has found that social support and an online sense of community can be developed through computer mediated communication channels. This study aims to gain an understanding of the benefits that membership of disability specific online communities may have for people with a physical disability. An online survey was administered to a sample of users of such sites (N = 160). Results indicated that users did receive moral support and personal advice through participating in such online communities. Further, results indicated that online social support and feeling a sense of community online were positively associated with partic...
British Columbia Hydro's new corporate strategic plan now recognizes two special responsibilities: to the province's native peoples and to the people of the Columbia River Basin. Eight strategic initiatives in the categories of obligations, investments, and opportunities are outlined. Four initiatives are aimed at meeting moral obligations: to pursue employment equity, to establish mutually beneficial business relationships with native peoples, to develop and maintain a leadership role in environmental stewardship, and to ensure a fair annual return on investment to the province. Two initiatives will see investments of strategic importance to British Columbia's future in the areas of job creation and economic progress throughout the province, notably in the Columbia River Basin. The final two initiatives concern development of export markets for the utility's technical services and ...
We consider propagation of relativistic heavy nuclei injected by a young pulsar into the radiation field of a massive companion. If the binary system (BS) is compact enough, then the nuclei suffer multiple photodisintegrations in collisions with thermal photons coming from the massive star (MS). Due to the propagation effects of charged particles in the magnetic field of the MS some hadrons can impinge onto the MS surface at large angles. We calculate the fluxes of produced neutrinos as a function of the viewing angle measured from the plane of the BS. It is found that significant fluxes of neutrinos should be also expected in the case of non-eclipsing BSs.
The Northwest Foster Care Alumni Study examined the relation between experiences in foster care and depression among young adults who spent at least a year in foster care as adolescents. Results indicate that preparation for leaving foster care, nurturing supports from the foster family, school stability, access to tutoring, access to therapeutic service and support, and a shorter and more stable placement history were associated with a lower probability of depression in young adulthood. Results provide evidence that suggest ways to improve practice to decrease rates of depression among alumni of care. (Contains 2 tables.)
We have implemented a virtual Young's double slit experiment for hard X-ray photons with micro-fabricated bi-prisms. We observe fringe patterns with a scintillator, and quantify interferograms by detecting X-ray fluorescence from a scanned 30nm Cr metal film. The observed intensities are best modeled with a near-field, Fresnel analysis. The maximum fringe number in the overlap region is proportional to the ratio of real to imaginary parts refractive index of the prism material. The horizontal and vertical transverse coherence lengths at beamline APS 8-ID are measured.
In this study the results of mathematical simulation and experimental research of texture transition in stress assisted shear phase transformations are discussed. The orientation distribution function (ODF) calculation model to the any type crystalline lattice symmetry materials has been suggested. By crystalline lattice symmetry analysis this computer program determines necessary amount of the initial experimental data. The experimental verification supports this model well. The ODF calculation model after shear phase transformation with equal use of all possible variants of orientation relationship or with various degrees of variant selection worked out. In this study the experimental and calculating data of the direct and reversal shear transformations #alpha# <=> #gamma# in Fe-alloys and B2 <=> B19' in Ti-Ni alloys are discussed. The stress assisted shear phase transformation model and computer program to calculate ODF after ...
In the last decade, directed evolution has become a routine approach for engineering proteins with novel or altered properties. Concurrently, a trend away from purely 'blind' randomization strategies and towards more 'semi-rational' approaches has also become apparent. In this review, we discuss ways in which structural information and predictive computational tools are playing an increasingly important role in guiding the design of randomized libraries: web servers such as ConSurf-HSSP and SCHEMA allow the prediction of sites to target for producing functional variants, while algorithms such as GLUE, PEDEL and DRIVeR are useful for estimating library completeness and diversity. In addition, we review recent methodological developments that facilitate the construction of unbiased libraries, which are inherently more diverse than biased libraries and therefore more likely to yield improved variants. PMID:16095966
The non-perturbative validity of covariant BRST-quantization of gauge theories on compact Euclidean space-time manifolds is reviewed. BRST-quantization is related to the construction of a Topological Quantum Field Theory (TQFT) of Witten type on the gauge group. The criterion for the non-perturbative validity of the quantization is that the partition function of the corresponding TQFT does not vanish and that its (equi-variant) BRST-algebra is free of anomalies. I sketch the construction of a TQFT whose partition function is proportional to the generalized Euler-characteristic of the coset space S U (n){sub gauge} / SU(n){sub global} with an associated equi-variant BRST-algebra that manifestly preserves translational symmetry. Some non-perturbative consequences of this approach are discussed. (author)
From out of the numerous technical alternatives the manual develops a waste management concept with emphasis on methods which can be coordinated for maximum ecological use and minimum economic costs. A clear-cut analysis of the present state of waste utilization and waste disposal in the Federal Republic of Germany (chapter 1) is followed by a detailed description of conventional and modern state-of-the-art waste utilization methods based on ecological evaluation criteria (chapter 3). An optimum waste utilization concept for defined quantities of wastes is derived from the ecological and economic comparison of waste utilization techniques given in chapter 3. Chapter 4 points out different variants of waste utilization and waste disposal methods and shows how to determine the optimum variant of the optimum concept for a particular area or community. (orig.).
The World Health Organization (WHO) estimates that as many as 80% of the world's more than six billion people rely primarily on animal and plant-based medicines. The healing of human ailments by using...Full Text Available
The protozoan parasite Trypanosoma cruzi is the etiologic agent of Chagas disease, a neglected tropical infection that affects millions of people in the Americas. Current chemotherapy...Full Text Available
BackgroundExisting studies concerning the health care use of homeless people describe higher utilisation rates for hospital-based care and emergency care, and lower rates for primary...Full Text Available
Sunbed use is associated with increased risk of melanoma. Younger people might be more susceptible to the carcinogenic effects of ultraviolet radiation. We investigated the association between...Full Text Available
This book chapter discusses sugarcane culture and history, describes arthropod biologies and injury, and identifies sugarcane pest management factors to consider for people interested in commercial sugarcane production. Arthropod groups include 10 orders and 40 families. Sugarcane pest management ...
The Space Task Group in its study of future directions in space, with ..... almost $6 billion and a peak civil service and contractor work force of 420000 people. ..... space organizations permitting assumptions of primary or joint responsibility for ...
As the presence of humans in space expands in scope and duration, the quality of life in space as well as on Earth becomes pertinent. .... Military uses of space, such as the introduction of space-based laser or particle beam weapons, may have a major impact on the way people think and relate to .... AIAA Student Journal. ...
BackgroundFor hundred of years, people in the region encompassed by the Afghanistan-Iran-Pakistan borders (AIP region) have been challenged by conflict and political and civil instability,...Full Text Available
of Colorado at Boulder Search This Site Natural Hazards Observer Disaster Research CU Web Site CU People go Search This Site Natural Hazards Observer Disaster Research CU Web...
ObjectiveThis study assessed the relationship between multiple indicators of ‘real-world’ functioning and scores on a brief performance-based measure...Full Text Available
The presence of Legionella spp. in the water of a Portuguese spa was ascertained during the spa season, between May and November. Simultaneously the prevalence of anti-legionella antibodies in people...Full Text Available
Purpose.To estimate the prevalence of early and late age-related macular degeneration (AMD) in India.Methods.Of 7518 people aged 60 years and older...Full Text Available
Skin sensitization is the most commonly reported occupational illness, causing much suffering to a wide range of people. Identification and labeling of environmental allergens is urgently required to...Full Text Available
To resolve the phylogeny of the autochthonous mitochondrial DNA (mtDNA) haplogroups of India and determine the relationship between the Indian and western Eurasian mtDNA pools more precisely, a diverse...Full Text Available
The appearance of hair plays an important role in people’s overall physical appearance and self-perception. With today’s increasing life-expectations, the desire to look youthful plays...Full Text Available
Despite the health-related benefits of exercise, many people do not engage in enough activity to realize the rewards, and little is known regarding the genetic or environmental components that account...Full Text Available
...Programme Manager Interests Multilevel Statistical Modelling Geography of Health and Health Care Geographical Data Analysis Census Data Analysis Health Services Research (in particular Research Design, Statistical Analysis and Epidemiology) people/mgould.html Homepage | Contacts | Site Map | Privacy Statement | Webmaster | ...
Approximately 400 people die from extreme heat each year in the United States, and the risk of heat waves may increase as a result of global climate change. Despite the risk of heat-related morbidity...Full Text Available
The future lubricants could be vegetable oils in order to replace the petroleum products. Vegetable oils are biodegradable and inoffensive for environment and for people. The main uses of vegetable oils are indicated. (O.L.). 3 refs., 3 tabs.
ObjectiveTo assess the efficacy and safety of low dose adrenaline injected subcutaneously to prevent acute adverse reactions to polyspecific antivenom serum in patients admitted...Full Text Available
Objectives To understand the perspectives of people with severe chronic obstructive pulmonary disease (COPD) as their illness progresses, and of their informal and professional carers,...Full Text Available
The selection due to the "healthy worker effect" was estimated from a random sample of the total Finnish population. The sample of 20 000 people was followed for changes in occupations from 1960 to...Full Text Available
Objective To compile and evaluate the evidence on the effects on health and social outcomes of computer based peer to peer communities and electronic self support groups, used by people...Full Text Available
... different personal wellness goals for you. HIV Health Management With a good medical team and a desire to reach wellness goals , people with HIV can have a virtually normal lifespan. Take the HIV Wellness Quiz Test your knowledge and find out where you need to learn ...
BackgroundAt least some forms of breast cancer are increasingly being viewed as a chronic illness, where an emphasis is placed on meeting the various ongoing needs of people living...Full Text Available
BackgroundOsteoporosis affects over 200 million people worldwide, and represents a significant cost burden. Although guidelines are available for best practice in osteoporosis, evidence...Full Text Available
Will the aging of Canada's population bankrupt the health care system? In this issue (see pages 1555 to 1560) Dr. Marie Demers reports that the increase in physician service costs for elderly people...Full Text Available
Hookworms, bloodfeeding intestinal nematodes, infect nearly one billion people in resource limited countries and are a leading cause of anemia and malnutrition. Like other nematodes, hookworms...Full Text Available
Objective:To assess the awareness and attitude of the general public toward people living with HIV/AIDS (PLWHA) in Mangalore, a city in Coastal Karnataka.Full Text Available
Objective: Health information retrieval (HIR) on the Internet has become an important practice for millions of people, many of whom have problems forming effective queries. We have developed...Full Text Available
Hundreds of thousands of people worldwide live or work in close proximity to steel mills. Integrated steel production generates chemical pollution containing compounds that can induce genetic damage...Full Text Available
...global warming problem became undeniable ...as global warming are a number also review they world energy ...global warming temperatures on the models and people take what's called ...? story combat global warming conservation ...
The national standards and state derivatives must be reinforced by models of curricular reform. In this paper, ARISE presents one model based on a set of principles--coherence, integration of the sciences, movement from concrete ideas to abstract ones, inquiry, connection and application, sequencing that is responsive to how people learn.
AIM: To examine the determinants of maternal-neonatal transmission of hepatitis B virus (HBV).METHODS: A nested case-control study was conducted in Changsha, Hunan, People’s Republic...Full Text Available
This article presents the text of a lecture delivered by American Educational Research Association President Carol D. Lee at the 29th Annual Charles H. Thompson Lecture-Colloquium Series which was held on November 5, 2008. In her lecture, Lee discussed several points of similarities between W. E. B. Du Bois and President Barack Obama. These similarities in background, education, and in their ideas on politics and power are historically connected with implications for educating Black people though race consciousness.
AbstractObjective To review studies investigating the brain correlates of unawareness of cognitive and behavioural symptoms in people with dementia. Design A detailed search of the literature was conducted to include all the peer-reviewed studies published in English aimed at identifying the structural or functional brain correspondents of unawareness in dementia patients. Their results were interpreted in relation to the methodological differences in terms of type of dementia studied, the protocol adopted to measure lack of awareness, the imaging techniques employed, the experimental designs and statistical analyses performed. Results Eighteen studies undertaken to explore the functional and structural correlates of unawareness of cognitive symptoms in dementia were identified. Although t...
A 7-kb genomic segment containing the coding sequence for the Drosophila melanogaster Formosa variant of salivary gland secretion protein 3 (sgs3) has been inserted into the snw y, bw, st strain of...Full Text Available
Gastrin and its carboxyl-terminal homolog cholecystokinin (CCK) exert a variety of biological actions in the brain and gastrointestinal tract that are mediated in part through one or more G protein-coupled...Full Text Available
Protein tyrosine phosphatase nonreceptor type 22 (PTPN22) gene polymorphisms are associated with many autoimmune diseases. The major risk allele encodes an R620W amino acid change that...Full Text Available
Attempts to synthesize YPd[sub 2]Si-type representatives LnPd[sub 2]Al were successful only with Ln triple bond Ce, Pr, Nd. This orthorhombic structure (oP16; space group Pnma) is an ordered variant of the Fe[sub 3]C type. Only NdPd[sub 2]Al undergoes magnetic ordering above 2 K. (orig.)
Inhibition of large conductance calcium-activated potassium (BKCa) channels mediates, in part, oxygen sensing by carotid body type I cells. However, BKCa channels remain active...Full Text Available
BackgroundSelection of hepatitis B virus (HBV) by host immunity has been suggested to give rise to variants with amino acid substitutions at or around the 'a' determinant...Full Text Available
Histone H3 mRNAs were found in polyA(+) fractions of total RNA prepared from alfalfa plants, calli and somatic embryos. The sequence analysis of cDNAs revealed the presence of a polyA tail on independent...Full Text Available
It is demonstrated that normal pitting can occur during oxidizing conditions in the repository. It is also concluded that a new theory for pitting corrosion has to be developed, as the present theory is not in accordance with all practical and experimental observations. A special variant of pitting, based on the growth of sulfide whiskers, is suggested to occur during reducing conditions. However, such a mechanism needs to be demonstrated experimentally. A simple calculational model of canister corrosion was developed based on the results of this study. 69 refs, 3 figs.
Mutation breeding in one of the cultigens TMV-5 in Sesamum is undertaken with 5 kr, 10 kr, 15 kr, 20 kr, 60 kr and 80 kr, dosages of gamma-rays. 60 kr and 80 kr dosages were found to be lethal from the complete failure of seed germination. The mutagen had a heterotic effect on the different characters and the promising variants obtained in this programme are proposed to be maintained by pureline breeding for their possible release as new varieties. (author).
Among important candidates for babesial vaccines are apical complex proteins, including rhoptry-associated protein 1 (RAP-1) from Babesia bovis and B. bigemina, which...Full Text Available
A great deal of energy is necessary to manufacture castings, the greater part of which is wasted. Some general instructions are given on how to keep this part as low as possible. This is discussed particularly using the example of a heat recovery plant for foundries, especially in the melting and cooling of castings with the use of cupola furnace stack gas to produce hot gas. Further variants for recovering heat from the individual stages of a foundry process are listed. There are data on using this heat in operation.
Sphingomonas paucimobilis B90A contains two variants, LinA1 and LinA2, of a dehydrochlorinase that catalyzes the first and second steps in the metabolism of hexachlorocyclohexanes (R....Full Text Available
We report the emergence of Salmonella enterica isolates of serotype Concord (and its monophasic variant 6,7:l,v:-) producing the extended-spectrum β-lactamases (ESBLs) SHV-12...Full Text Available
BackgroundTrisomic variants of human embryonic stem cells (hESCs) arise spontaneously in culture. Although trisomic hESCs share many properties with diploid hESCs, they also exhibit...Full Text Available
We study a variant of the Penner-Distler-Vafa model, proposed as a c = 1 quantum gravity: quenched' matrix model with logarithmic potential. The model is exactly soluble, and exhibits a two-cut branching as observed in multicritical unitary matrix models and multicut Hermitian matrix models. Using analytic continuation of the power in the conventional polynomial potential, we also show that both the Penner-Distler-Vafa model and our quenched' matrix model satisfy Virasoro algebra constraints.
Case-parent trios were used in a genome wide association study of cleft lip with/without cleft palate (CL/P). SNPs near two genes not previously associated with CL/P [MAFB:...Full Text Available
This paper reports the findings of a study that explores the perspectives of 25 young Cypriots regarding the symbolic values of smoking with respect to their everyday lived experiences. This study was motivated by recognising the high levels of smoking prevalence among adolescents in Cyprus and the absence of published research 'recording' their own versions of reality about smoking. Data for the study were generated from one-to-one qualitative interviews which encouraged the participants to articulate the symbolic value of smoking in their day-to-day experiences. The analysis focuses first, on the content of the embedded symbolic values of smoking (e.g. the quality of being 'cool') and second on the role of these values (e.g. used in projecting an image) in their everyday lives. A central...
There is evidence that aged normal subjects have more difficulty in achieving automaticity than young subjects. The underlying central neural mechanism for this phenomenon is unclear. In the present study, functional magnetic resonance imaging (fMRI) was used to investigate the effect of normal ageing on automaticity. Aged healthy subjects were asked to practice self-initiated, self-paced, memorized sequential finger movements with different complexity until they could perform the tasks automatically. Automaticity was evaluated by having subjects perform a secondary task simultaneously with the sequential movements. Although it took more time, most aged subjects eventually performed the tasks automatically at the same level as the young subjects. Functional MRI results showed that, for bot...
Bisphenol-A (BPA) is one of the most common environmental endocrine disrupters and has a wide range of effects on central nervous system. Adolescence is another important developmental period besides the early critical prenatal and neonatal periods. In the present study, we exposed mice to BPA (40, 400 mg/kg/d) between adolescence and young adulthood for 8 weeks and investigated its effects on the non-reproductive behaviors. In open field tests, rearing and grooming sex differences were abolished by BPA exposure. In the elevated plus maze test, the number of open arm entries, the time spent in open arms, and the number of unprotected head dips in the center area were reduced in males but increased in females by BPA at 40 or 400 mg/kg/d, thus eliminating or reversing sex differences in thes...
ObjectivesThe International Network for Young Scientists is holding a China:UK workshop in Shanghai in December. It will focus specifically on Renewable Energy. Profs Wallace and Infield have been invited to be the UK academic partners. Dr. Luo Yong Hao, Deputy Director of Institute for Thermal Engineering at Shanghai Jiao Tong University is the lead Chinese academic partner. British Council Shanghai are the co-ordinators of the event and have obtained some limited funding to cover the costs.. ~%~~%~T [continued...]DescriptionReseachers are being brought together at a China:UK Renewable Energy Research Workshop. They will define and initiate joint research and staff/student exchanges between Chinese and UK universities to advance renewable energy and related research to meet the energy needs of both China and the UK.~%~
Effect of oil palm empty fruit bunch (OPEFB) fiber and poly(methyl acrylate) grafted OPEFB on several mechanical properties of poly(vinyl chloride)/epoxidized natural rubber (PVC/ENR) blends were studied. The composites were prepared by mixing the fiber and the PVC/ENR blends using HAKEE Rheomixer at the rotor speed of 50 rpm, mixing temperature 150degreeC, and mixing period of 20 min. The fiber loadings were varied from 0 to 30% and the effect of fiber content in the composites on their ultimate tensile strength (UTS), Youngs modulus, elongation at break, flexural modulus, hardness, and impact strength were determined. An increasing trend was observed in the Youngs modulus, flexural modulus, and hardness with the addition of grafted and ungrafted fiber to the PVC/ENR blends. However the i...
In a series of experiments carried out on young and adult rabbits the effect of isocaloric low protein diets containing 4% or 8% protein compared with a diet containing 21% protein on Obeliscoides cuniculi infection was studied. The pathogenesis, resistance and local immunity were assessed after single infections with 10,000 larvae or reinfection with 5000 larvae. Live weight gain was reduced in young and adult rabbits fed the low protein diets, but the establishment of parasites was not substantially influenced by protein deprivation. However, development of worms in the histotrophic phase and parasite fecundity were impaired in association with the low protein diet. Moreover, mild anaemia as well as changes in the mucosal immune response as a result of infection were related to the level of dietary protein. (author). 30 refs, 6 figs, 5 tabs.
Bilateral breast carcinoma accounts for approximately 5% of all patients with breast cancer, while neuroendocrine breast carcinomas comprise less than 5% of invasive breast carcinomas. In addition, most patients with breast neuroendocrine carcinomas are older. Therefore, bilateral primary breast neuroendocrine carcinoma at a young age is extremely rare. We herein report bilateral neuroendocrine carcinoma of the breast in a 29-year-old woman who underwent bilateral lumpectomy with the initial symptom of bilateral nipple discharge. Grossly, the lesions in both breasts were masses with infinite margins. Histologically, this case was consistent with primary neuroendocrine carcinoma arising in bilateral breasts. Cells from both breast tumors were positive for chromogranin A, neuron-specific eno...
Abstract Micronutrient deficiencies are a public health concern among young children in low-income countries, and novel strategies are needed to improve the nutritional status of children at risk. One promising approach is the use of lipid-based nutrient supplements (LNS), which can be added to complementary food at the time of consumption. The optimal amount of zinc to include in LNS is uncertain, and concerns have been expressed about possible adverse effects of zinc on sensory characteristics of LNS. We conducted a series of acceptability studies of LNS containing either 0 or 10-mg of zinc per daily 20-g LNS dose among Burkinabe children 9-15 months old and their mothers. These acceptability studies included observations of children's consumption, maternal and child sensory reaction to ...
The survival of acetabular components depends on several factors: wear, osteolysis and septic or aseptic loosening. Osteolysis seems to be the main cause for concern in cementless arthroplasties. Acetabular osteolysis results from particle debris and segmental unloading of acetabular bone by rigid sockets. We investigated a cementless elastic monoblock socket with regard to acetabular osteolysis and aseptic loosening in a cohort of young patients. We evaluated 158 hip arthroplasties with a minimum follow-up of ten?years (ten to 18) and a mean age of 42?years (18?50). The overall revision rate at 14?years was 80% with a 98% survival rate for aseptic loosening. The mean polyethylene wear rate was 0.11?mm/year. Progressive acetabular osteolysis was seen in 3% of patients evaluated. In conclus...
This paper presents an overview of issues related to surface water contamination arising from uranium mining activities in the Alligator Rivers Region (ARR) of northern Australia, and a program of research and monitoring that must assess the potential and actual effects on ecosystem and human health. The program of assessing effects on aquatic ecosystems involves a four-tiered approach including the derivation of local water quality guideline trigger values, direct toxicity assessment of mine waters prior to their release, creekside or in situ monitoring for early warning of adverse effects during mine water release, and longer-term monitoring of macroinvertebrate and fish communities. Bioaccumulation in aquatic biota is also assessed, and is an issue of importance not only to ecosystem health, but also to the health of local Aboriginal people. The aquatic animals they consume represent potential sources of radiological dose, and as a result, a major component of ...
Aims: Serotonin (5-hydroxytryptamine 3; 5-HT3) receptors are involved in chemotherapy-induced nausea and vomiting (CINV), and 5-HT3 antagonists are part of the `gold standard' antiemetic treatment during chemotherapy. We investigated the correlation of common variants in 5-HT3 receptor subunit genes with the occurrence of CINV. Materials & methods: A total of 110 previously characterized chemotherapy-naive women with primary breast cancer treated with anthracycline-containing chemotherapy served as a study group for mutational analysis by direct sequencing. Eight common SNPs in the 5-HT3 receptor genes, HTR3A, HTR3B, HTR3D and HTR3E, were selected for association analysis. Results: A nonsynonymous variant in HTR3D, p.G36A (rs6443930), was found to be over-represented in nonresponders, assu...
Protocols were standardized for in vitro propagation of several elite and diverse banana accessions using shoot tip explants. Tissue culture raised plants were field planted at multiple locations. Studies were undertaken for the induction of mutations using multiple shoot cultures of six selected cultivars, Shreemanti (AAA), Basrai (AAA), Lal Kela (AAA), Rasthali (AAB), Karibale Monthan (ABB) and a wild diploid (BB). These shoot cultures were irradiated at different doses of gamma rays (0-100 Gy) and subcultured thrice (up to M_1V_3) to separate shimeras, followed by induction of rooting (M_1V_4). In general, the rate of multiplication had a negative association with the dose of gamma rays. Enhanced multiplication of shoots was noticed at lower doses. The proliferation of shoots was arrested beyond 50 Gy and a dose of 70 Gy was completely lethal for all the genotypes studied. The rooted plantlets were hardened in the green house and in the early stages of field growth, a few ...
A novel single-chain immunotoxin was constructed by combining a CD33-specific single chain Fv (scFv) antibody fragment with an engineered variant of Pseudomonas exotoxin A (ETA). The variant toxin carries the KDEL peptide at its C-terminus, a cellular peptide mediating improved retrograde transport to the endoplasmic reticulum. The purified recombinant fusion protein induced potent apoptosis of the human myeloid cell lines U937, HL-60 and THP-1. Up to 98% of U937 cells were eliminated after treatment for 72 h with a single dose of 500 ng/ml (c. 7 nmol/l). Killing was antigen-specific and occurred by apoptosis. A control protein, consisting of a CD19-specific scFv antibody fragment fused to the ETA-KDEL toxin, failed to induce death of the CD19-negative cell lines U937, HL-60 and THP-1. The CD33-ETA toxin also mediated apoptosis of fresh patient-derived acute myeloid leukaemia cells from bone marrow and peripheral blood. The pronounced ...
For years, the writing has been on the wall about the impact of climate change on the people, plants, animals, and habitats of Latin America and the Caribbean. Now, day-to-day experiences and eye-witness accounts from leading environmental and development groups are proving predictions to be correct. In the late 1990s, the world's pre-eminent group of climate scientists gathered under the Intergovernmental Panel on Climate Change (IPCC) and predicted a devastating range of impacts, including an increase in the intensity and number of extreme weather events exacerbating natural disasters, forest die-off, melting glaciers, and the drying out of temperate grasslands. The region's huge geographical diversity means that patterns of vulnerability to climate change are extremely varied. It also makes modelling difficult, although this is constantly improving. To avoid misunderstanding, it is important to point out that with or without global warming, ...
After the reactor accident at Chernobyl on April 26, 1986 radioactive fallout was carried by air currents to most parts of Europe. The radioactive air currents reached Finland on April 27. Immediately after the arrival of such air in Finland, contamination of people by radioactive nuclides began via inhalation of this air. The ingestion route become important later, when radionuclides were transported via different foodchains to man. To determine the level of radionuclides in the body and to estimate the internal radiation doses caused by the Chernobyl accident, whole-body counting measurements were performed. The results of whole-body counting of six different groups of Finnish people measured during 1986 after the accident at Chernobyl are reported. Three were reference groups measured routinely once or twice annually, two groups were comprised of workers at nuclear power stations and one group consisted of 262 persons not belonging to any ...
In this paper we have investigated the performance of PSO Particle Swarm Optimization based clustering on few real world data sets and one artificial data set. The performances are measured by two metric namely quantization error and inter-cluster distance. The K means clustering algorithm is first implemented for all data sets, the results of which form the basis of comparison of PSO based approaches. We have explored different variants of PSO such as gbest, lbest ring, lbest vonneumann and Hybrid PSO for comparison purposes. The results reveal that PSO based clustering algorithms perform better compared to K means in all data sets.
... (restricted)] 251-260 Revisiting new variant famine: the case of Swaziland by Scott Naysmith & Alex Waal & Alan Whiteside [Downloadable! (restricted)] 261-269 Food prices and the HIV response: findings from rapid regional assessments in eastern and southern Africa in 2008[InlineMediaObject not available: see fulltext.][InlineMediaObject not available: see fulltext.] by Stuart Gillespie & Paul Jere & John Msuya & Scott Drimie [Downloadable! (restricted)] 271-289 Declining global per capita agricultural production and warming oceans ...
A 60-year-old male was bitten by a venomous snake (Vipera ammodytes) and gradually developed signs of an allergic reaction including generalized itching, generalized rash, and chest discomfort. This was followed by severe retrosternal pain with electrocardiographic evidence of an inferior myocardial ischemia progressing to acute myocardial infarction. Cardiac enzymes and troponin, serum tryptase, and histamine were elevated. Coronary arteriography showed normal coronary arteries. This is a characteristic type I variant of Kounis syndrome, which is the concurrence of acute coronary syndromes with conditions associated with mast cell activation including allergic or hypersensitivity reactions as well as anaphylactic or anaphylactoid reactions. This is the first report to show that viper bite...
We study a generalization of the classical Riemannian Tonnetz to N-tone equally tempered scales (for all N) and arbitrary triads. We classify all the spaces that result. The torus turns out to be the most common possibility, especially as N grows. Other spaces include 2-simplices, tetrahedra boundaries, and the harmonic strip (in both its cylinder and Mobius band variants). The final and most exotic space we find is something we call a 'circle of tetrahedra boundaries'. These are the Tonnetze for spaces of triads which contain a tritone. They are closely related to Peck's Klein bottle Tonnetz.
This largely expository paper first gives an introduction to Hilbert stability and its use in Gieseker's GIT construction of $\\overline{M}_g$. Then I review recent work in this area--variants for unpointed curves that arise in Hassett's log minimal model program, starting with Schubert's moduli space of pseudostable curves, and constructions for weighted pointed stable curves and for pointed stable maps due to Swinarski and to Baldwin and Swinarski respectively. The focus is on the steps at which new ideas are needed. Finally, I list open problems in the area, particularly some arising in the log minimal model program that seem inaccessible to current techniques.
This paper describes the study of kinetically controlled enzymatic coupling of N- and O-glycopeptide fragments using subtilisin BPN' and two of its variants developed for use in high concentrations of dimethylformamide and in aqueous solution, respectively. Glycosyl amino acids were exploited as the P[sub 1], P[sub 2], P[sub 3], P'[sub 1], P'[sub 2], or P'[sub 3] residue in the enzymatic coupling. Glycosyltransferase-mediated glycosylation of the glycopeptide fragments obtained prior to or after enzymatic peptide bond formation is demonstrated. 19 refs., 5 figs., 1 tab.
The cubature Kalman filter (CKF) is a relatively new addition to derivative-free approximate Bayesian filters built under the Gaussian assumption. This paper extends the CKF theory to address nonlinear smoothing problems; the resulting state estimator is named the fixed-interval cubature Kalman smoother (FI-CKS). Moreover, the FI-CKS is reformulated to propagate the square-root error covariances. Although algebraically equivalent to the FI-CKS, the square-root variant ensures reliable implementation when committed to embedded systems with fixed precision or when the inference problem itself is ill-conditioned. Finally, to validate the formulation, the square-root FI-CKS is applied to track a ballistic target on reentry.
Full text of publication follows: Radiation hardening and embrittlement due to high-energy neutron radiation around 623 K are the important issues on reduced-activation ferritic/martensitic (RAF/M) steels. It is expected that the improvement of radiation hardening might be one of effective ways to control the mechanical properties of RAF/M after irradiation. It has been reported that the weld joint has less hardening than the base metal from the tensile test results of TIG weldments irradiated in HFIR. This report indicated that radiation hardening can be reduced by the optimization of heat treatment condition for F82H. The purposes of this study are to establish the condition of heat treatment for minimum of radiation hardening in F82H steel using Neutron/Ion-irradiation and to examine a correlation between tensile property and micro-hardness before/after irradiation. The materials used in this study were F82H IEA heat and F82H heat treatment variants. Neutron ...
Difficulty in recalling the names of people is very common in the early stages of Alzheimer's disease and in mild cognitive impairment (MCI). However, it is not known whether the difficulty in naming people in MCI reflects problems associated with lexical access or with semantic access. The aims of the present study were to investigate semantic and phonological access to proper names by use of a Tip-of-the-tongue (TOT) task in individuals with multidomain amnestic MCI, individuals with amnestic MCI, and healthy controls, as well as to study the relationships between TOT production and performance in a free recall verbal memory test. In the individuals with multidomain amnestic MCI, the main process affected was phonological access; failures in phonological access were related to deficits i...
This study was developed as part of the project ?Studies for Environmental and Cultural Sustainability of the Fulni-? Medical System: Office on handling medicinal plants?. The Fulni-? people are located in Pernambuco State, Northeastern Brazil. One of the components of this project was an ethnobotanical diagnosis of the indigenous land, where a phytosociological survey was performed in an area of Caatinga vegetation, located at Ouricuri settlement. Based on these ethnobotanical data, we calculated a conservation priority index aiming to rank species that should receive immediate attention from the Fulni-? people. We identified 44 woody plants, 50% of which have a medicinal use. Among these, six plants were considered highly vulnerable and in need of immediate conservationist attention, in ...
Long before possible organic effects, exposure to ionizing radiations can provoke anxiety. In front of invisibility, the imagination quickly ignites. The terrorists have perfectly understood it. They are ready to use ionizing radiations as a weapon to remind traumatic images deeply rooted in people's memory. These images induce anxiety with all the clinical expressions connected to it. These symptoms require to be treated because of a possible anarchic development. For that purpose, plans have been elaborated to coordinate the different professional's actions. The coherence of medical management and communication aims to allow the most implicated people to find the way to face the events. When it is not possible, medico-psychological cells permit a specialized care. (author)
This issue of Carbon Market Perspectives on 'Pathways for implementing REDD+: Experience from carbon markets and communities' discusses the role of carbon markets in scaling up investments for REDD+ in developing countries. Nine articles authored by experienced negotiators on REDD+, carbon market actors, project developers and other leading experts share experiences and make suggestions on the key elements of a future international REDD+ regime: Architecture and underlying principles, measuring, reporting and verification (MRV), private-sector involvement, the rights of indigenous people and local communities, biodiversity conservation and environmental integrity. The articles are grouped under three main topics: the lessons of existing REDD+ projects; the future REDD+ regime and the role of carbon markets; and experiences and ideas about the involvement of indigenous people and local communities. (LN)
The diversity of plant resources in the Brazilian semi-arid region is being compromised by practices related to agriculture, pastures, and forest harvesting, especially in areas containing Caatinga vegetation (xeric shrublands and thorn forests). The impact of these practices constitutes a series of complex factors involving local issues, creating a need for further scientific studies on the social-environmental dynamics of natural resource use. Through participatory methods, the present study analyzed people?s representations about local environmental change processes in the Brazilian semi-arid region, taking into consideration local production systems, natural resources, and their importance. Environmental historical graphs were developed with nine local families to analyze landscape cha...
Summary Indigenous people demonstrably lived along rivers and around lakes and wetlands of Australia's Murray-Darling Basin in pre-European times. Waterways were, and continue to be, of major significance to the society and culture of Aboriginal peoples throughout Australia. Historically, they exploited most of the fauna - from mussels and crayfish, to fish and birds - and either ate, or used for other purposes, many species of aquatic plants. Such practices placed them in the role of environmental modifiers, a role played by all human groups from both past and present. They built sophisticated fish traps, cut gaps in river banks to allow fish to move on to floodplains, and there is evidence that they practised a form of fish culture by creating small impoundments in which small fish could...
This study was designed to identify the relationship between free time management and quality of life, exploring whether the amount of free time or the way people using their free time relates to their quality of life. Data were collected from National Pingtung University of Science and Technology in Taiwan. Of the 500 questionnaires distribute, 403 usable questionnaires were received with an 81% response rate. The result has found a positive relationship between free time management and quality of life. Contrary to this, there was no significant relationship between time allocation and quality of life. Results might indicate that people who manage their free time well lead to better quality of life. Suggestions based on the observed relationship and directions for future researches were d...
Purpose - In light of the growth of internet usage and its important role in the field of e-commerce, electronic word-of-mouth (eWOM) has been changing people's behavior and decisions. People count on other users' opinions and information; they sometimes even make offline decisions based on information acquired online. The purpose of this paper is to conceptualise eWOM activity from an input-process-output (IPO) perspective; propose a classification framework based on the identified academic literature; analyze eWOM literature in terms of quantitative development and qualitative issues that are useful to both academics and researchers; and provide directions and guidelines for future research studies in eWOM. Design/methodology/approach - The authors performed a systematic literature revie...
Colorectal cancer (CRC) is the most common cause of cancer death among Canadian non-smokers. Each year about 21,500 Canadians are diagnosed with CRC. Ninety percent of cases occur in people aged 50 years or older. An estimated 4,800 Canadian men and 4,100 Canadian women die each year from the disease. About 75% of all new CRC cases arise in people with no known risk factors. Computed tomography colonography (CTC), a cross-sectional imaging examination that permits complete structural examination of the colon, shows promise as a tool for CRC screening. This article reviews the rationale for CRC screening, currently recommended Canadian and American screening guidelines and screening tools, and current evidence supporting CTC as a CRC screening tool and its advantages over conventional screening methods. (author)
Colorectal cancer (CRC) is the most common cause of cancer death among Canadian non-smokers. Each year about 21,500 Canadians are diagnosed with CRC. Ninety percent of cases occur in people aged 50 years or older. An estimated 4,800 Canadian men and 4,100 Canadian women die each year from the disease. About 75% of all new CRC cases arise in people with no known risk factors. Computed tomography colonography (CTC), a cross-sectional imaging examination that permits complete structural examination of the colon, shows promise as a tool for CRC screening. This article reviews the rationale for CRC screening, currently recommended Canadian and American screening guidelines and screening tools, and current evidence supporting CTC as a CRC screening tool and its advantages over conventional screening methods. (author)
The necessity of supporting more and more social interaction (and not only the mere information sharing) in online environments is the disruptive force upon which phenomena ascribed to the Web2.0 paradigm continuously bud. People interacting in online socio-technical environments mould technology on their needs, seamlessly integrating it into their everyday life. MUVEs (Multi User Virtual Environments) are no exception and, in several cases, represent the new frontier in this field. In this work we analyze if and how MUVEs can be considered a mean for augmenting communities (and more in general people) life. We trace a framework of analysis based on four main observations, and through these lenses we look at Second Life and at several projects we are currently developing in that synthetic world.
We hypothesize that the mushroom-derived active compound may be a potential strategy for increasing survival in response to influenza virus (H1N1) infection through the stimulation of host innate immune response. The validity of the hypothesis can be tested by immune response to influenza infection as seen through survival percentage, virus clearance, weight loss, natural killer cell cytotoxicity, Tumor Necrosis Factor-? (TNF-?) and Interferon-gamma (IFN-?) levels, lytic efficiency in the spleens of mice and inducible nitric oxide synthase mRNA expressions in RAW 264.7 murine macrophage cells. The hypothesis may improve people's quality of life, reduce the medical cost of our healthcare system and eliminate people's fears of influenza outbreak. PMID:21660092
A study conducted at the IHS had the aim to obtain basic information on whether it is possible to build flow turbines following the free jet principle that are on a par with, or superior to, the conventional design, especially in terms of performance and the efficiency curve. Several inflow contours with a ventilated free jet and a conventional flow turbine were studied. The direct comparison of these variants revealed a slightly enhanced peak load efficiency and a very distinct superiority of the free jet contour during partial load. But the efficiency of all variants failed to attain the values claimed by commercial manufacturers. As compared to the initial contour, peak load efficiency was enhanced by 5 per cent. During partial load, the variants studied showed a distinct superiority of the free jet concept over the contour of conventional flow turbines. (orig.) [Deutsch] Am IHS wurde eine Untersuchung mit dem Ziel ...
This report describes a technique of inserting an implantable venous access port (portacath) through a thrombosed and occluded vein employing a pre-existing peripherally inserted central catheter (PICC) as the route of access. The PICC was used as a conduit for venous access in a way that has not been described previously in the literature. This procedure was performed in a young patient with cystic fibrosis in an effort to prevent the use of his virgin contralateral veins, which might be used in the future.
This study examined preliminary psychometric properties of the Teaching Practices Observation Scale (TPOS), a newly developed observational taxonomy for assessing teacher behaviors during free play with young children. Behaviors of 42 child caregivers and junior kindergarten teachers were coded using a combination of time-sampling, event-sampling, and behavior ratings. Findings support the validity of observational coding scheme. (Author/KB)
...Site Home About The Project Advisory Board Advisory Board Kenneth Geiser Omar Friella Darryl Young Jennie Curtis Michael Maniates Stuart Baker Beverly Thorpe Erica Priggen Kenneth Geiser is Professor of Work Environment and Director of the Lowell Center for Sustainable Production at the University of Massachusetts Lowell. Ken is one of the authors of the landmark Massachusetts Toxics Use Reduction Act and served as Director of the Massachusetts Toxics Use Reduction ...
Lower respiratory tract infections are one of the leading causes of morbidity and mortality in children worldwide. Recent technological advances in the field of molecular biology have allowed virologists...Full Text Available
BackgroundThe Plasmodium falciparum pre-erythrocytic stage candidate vaccine RTS,S is being developed for protection of young children against...Full Text Available
A previously healthy young man experienced several episodes of syncope while being treated with tenofovir, emtricitabine and nevirapine initiated during primary HIV-1 infection. Symptoms disappeared after discontinuation of antiretroviral therapy and we suggest that syncope may be a side effect to one of the three antiretroviral drugs that has not been described previously.
DescriptionIn young pigs the post-weaning period is generally characterised by a marked reduction in voluntary feed intake, poor growth and development, and diarrhoea. The associated reduction in digestive and absorptive capacity of the gastrointestinal tract decreases the overall efficiency of nutrient capture and utilisation, thereby causing an increase in nutrient loading to the environment. The reduction in digestive and absorptive efficiency after weaning has implications for lifetime performance be [continued...
In male rodents, anogenital distance (AGD) provides a sensitive and continuous correlate of androgen exposure in the intrauterine environment and predicts later reproductive success. Some endocrine-disrupting chemicals can alter male reproductive tract development, including shortening AGD, in both rodents and humans. Whether AGD is related to semen quality in human is unknown.
Pneumococcal disease in young children has not been as well characterized in East Africa as it has been in industrialized countries. Although pneumococci are likely to cause substantial mortality...Full Text Available
Anaplastic lymphoma kinase-positive, anaplastic large cell lymphoma (ALK+ ALCL) is an aggressive non-Hodgkin lymphoma of T/null immunophenotype that is most prevalent in children and young adults. The...Full Text Available
... I worked on the Young City Farmers course in 2008, where I was voted the best-spoken bus driver and teacher the participants had ever had!! I am a representative of the University for widening participation and outreach, for my enthusiasm, communication and personal skills. I look forward to meeting you, welcoming you to the College and helping with your learning and progression. Sam Parkes Hi I'm ...
... Based in the Philippines, it has a broad remit, covering all philosophical topics, but with a particular focus on analytic ...net/ Cultura is a Romanian-based international journal devoted to philosophy of culture and axiology (the study of value). It aims ...edu/ Aporia is an online undergraduate philosophy journal based at Brigham Young University in Utah, USA. All articles are written by undergraduates,...edu/pcs/basic.html Theoretical and Conceptual Advances in the Cognitive Neuroscience of Self Representation: Representations of the Minimal Self in Self-Narrative is ...
... This is true because a shorter residence time means that ground water moves 'faster.' Thus, contamination will get to the drinking well from the recharge area (point of entry) faster if the ground water is younger. However, it has been difficult to measure the exact age of young ground water. The conventional indicator has been tritium, a radioactive form of hydrogen, but its ...
The paper intends to lay down the fundamentals of normal mineralisation in the perinatal phase as a basis for investigations of disturbed mineralisation. Data are presented on the percentage area of the mineralized osseous tissue, the osteocyte density, and the mineral contents of healthy bones at this age. Comparative morphological examinations of thin bone sections and microradiographs give a picture of bone development at this age. (orig./AJ).
The macroscopic behavior of magnetostrictive materials results from domain evolutions occurring at a microscopic scale. The author shows how to compute magnetization and magnetostriction curves by appraising the behavior of the underlying microstructures. The method hinges on an averaging device (Young measures), which allows one to pass from the microscopic to the macroscopic scale. He takes into account the kinematical constraints on the accommodation of elastic effects, and he highlights the role of material symmetry in the selection of energetically optimal microstructures.
Klippel-Feil Syndrome (KFS) is a congenital anomaly characterized by a defect in the formation or segmentation of the cervical vertebrae. The clinical triad consists of short neck, low posterior hairline and limited neck movement. Multiple congenital anomalies have been associated with this disease. This is a case of KFS in a young girl along with situs inversus, which is an extremely rare association. Various systemic associations occurring in this multi-system disorder are also discussed. (author)
Newly hatched chicks were dosed orally with a Salmonella typhimurium wild-type strain, an S. enteritidis wild-type strain, and a genetically defined S. enteritidis aroA vaccine candidate, strain CVL30....Full Text Available
...Older Siblings by Adriaan R Soetevent & Peter Kooreman 392-415 Vocational Training and Gender: Wages and Occupational Mobility among Young Workers by Bernd Fitzenberger & Astrid Kunze 416-438 Gender Role Attitudes and the Labour-market Outcomes of Women across OECD Countries by Nicole M Fortin 439-461 Gender, Time Use, and Public Policy over ...
The polymer industry is a young industry that has undergone tremendous growth and change over the last sixty years. Many important discoveries in polymer science have been accidental. Most of the learning has been by trial and error and most of the understanding is still basically empirical--make a polymer material or compound and then put it to the test to study what it is and how it performs. This article provides an overview of what polymers and polymer compounds are, why they behave as they do, and it discusses several examples of failures of rubber and plastic components.
Simulations of young stellar systems suggest that planets embedded in a circumstellar disk can produce many distinctive structures, including rings, gaps and spiral arms. This video compares computer simulations of hypothetical systems to an image of system SAO 206462 taken by the Subaru Telescope and its HiCIAO instrument. n nCredit: NASA Goddard Space Flight Center/NCSA
Bovine paratuberculosis is caused by infection of young calves with Mycobacterium avium subsp. paratuberculosis. In some of the chronically infected cows the long asymptomatic...Full Text Available
Experiments were conducted with field-grown cotton (Gossypium hirsutum L.) in 1985 and 1986 to determine effects of water deficit on levels of conjugated indole 3-acetic...Full Text Available
On the basis of symmetry way of texture description a calculation method of elastic moduli of two-phase titanium alloys with rolling texture has been suggested. Efficiency of the calculation formulas is checked by comparing the calculation results of Young modulus anisotropy in the sheet plane of (#alpha#+#beta#)-titanium alloy VT23 with the experimental data.
This is an account of the initial struggles and subsequently successful career of a young woman growing up in prewar Australia with the overriding desire to become a physicist despite various problems and prejudices. The book provides first-hand accounts of wartime radar research and development in Australia; the immediately post-war era in nuclear physics at the Cavendish Laboratory, Cambridge; and work in the Nuclear Physics Division at AERE Harwell in the period from the 1950s onwards. (UK).
Using QCT, we made a longitudinal, population-based assessment of rates of bone loss over life at the distal radius, distal tibia, and lumbar spine. Cortical bone loss began in perimenopause in women...Full Text Available
The Gordon Research Conference (GRC) on 2004 Gordon Research Conference on Reversible Associations in Structure & Molecular Biology was held at Four Points Sheraton, CA, 1/25-30/2004. The Conference was well attended with 82 participants (attendees list attached). The attendees represented the spectrum of endeavor in this field coming from academia, industry, and government laboratories, both U.S. and foreign scientists, senior researchers, young investigators, and students.
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Full text: The IRSN has been organizing enquiries with the French population about risk and risk perception for a long time. In 2002, a collaboration between the IRSN in France and the SCK.CEN in Belgium has been set-up to simultaneously (November 2002) organise this poll in both countries. In each country, a representative sample of the population (over 1000 participants per country) has been consulted by Computer Aided Personal Interviews of about 30 minutes with the professional help of commercial companies: BVA in France and Research International in Belgium. The enquiry yields a broad spectrum of interesting data; here only the results relevant for the emergency context will be presented. One should be aware that these data were collected in a 'normal' period; important differences in behaviour may occur given a serious crisis. A first finding is that more than half of the respondents are convinced that an accident as severe as the Chernobyl disaster may happen in their country as ...
BackgroundDue to improvements in cancer survival the number of people of working age living with cancer across Europe is likely to increase. UK governments have made commitments...Full Text Available
Ts presentation, available online as a printable PDF, discusses the global effects of deforestation. It contains the following three pages:an overview of the reasons people have cut forests and how the direct destruction of forests is the primary reason for today's massive extinction of speciesa world map that shows the global forest cover 8,000 years agoa world map that shows the significantly smaller remaining frontier forests as of 1997?intact natural forest ecosystems that are relatively undisturbed and large enough to maintain all of their biodiversity.
... Wanting to help a charity is commendable but the main focus of generosity should be the people in front of you, not your choice of spiritual overlord - especially so if the group is being funded with money from taxpayers. Recommend? (44) Report abuse | Link ...
The radiation burden of the people of the GDR in relation to biomedical radiography altogether as well as organ doses, gonad doses and genetically significant doses in detail are outlined. The concepts of radiation protection and standards of radiographic examination are demonstrated. Possibilities of influencing radiation exposure by scientifically based indication of X-ray examination, application of new and improvement of usual examination techniques are discussed with regard to quality assurance and control. Proposals concerning the reduction of radiation exposure of the GDR population are presented.
This comprehensive guide offers several tried and true steps to help you successfully manage the complex process of developing free software. Topics include project management, developer motivation, technical infrastructure to support collaboration, and project promotion. Producing Open Source Software is ideal for developers starting their own free software projects, or people who simply want to participate in the process.
The goal of this lecture is to give an overview of important concepts connected to organisational factors and to provide an understanding of mechanisms by which they can contribute to safe or unsafe behaviour of people. The lecture gives examples of ways to organise work, organisational deficiencies and good practices applied in safety oriented organisations. The lecture also gives an introduction to international work and Finnish national regulation connected to organisation and management. (orig.)
... Complete Wasters An exciting range of recycled, re-used, fairtrade and sustainable gifts as well as low cost recycled computer systems. Visit our mini eco centre, gift shop and wildlife garden. Since 1997 Complete Wasters has... recycled 700 tonnes of paper, card, cans, and bottles; refurbished 2000 PCs; planted 600 trees and promoted recycling to over 700,000 people at over ...
BackgroundIn an effort to promote healthy ageing and preserve health and function, the government of Chile has formulated a package of actions into the Programme for Complementary...Full Text Available
Traditionally, market researchers have sought some formula to predict the acceptance of a new product or innovation in advance of its introduction. Perhaps a universal marketing formula will never be found. However, a summary of 3000 research studies, conducted in the United States and in other countries of the world, on how people accept new ideas promises more insight into the subject of the marketing of passive design and products than ever before.
The statements given by the following people are included: Steven Dean, Edward Frieman, Zalman Shapiro, Lee Berry, Ronald Davidson, Kenneth Fowler, Melvin Gottlieb, and Tihiro Ohkawa. (MOW)
... Studies People Projects Opportunities Framework Critical Sectors Development Goals Geographic Region Geographic Scale Research Themes Printer-Friendly Center for Ocean Solutions Early Career Fellowship Program Location: Stanford, California Source: The Center for Ocean Solutions (“Ocean Solutions”) seeks one or more recent graduates who have received a JD, MBA or PhD in the natural, physical or social sciences in the last five years, and who ...
...Studies People Projects Opportunities Framework Critical Sectors Development Goals Geographic Region Geographic Scale Research Themes Printer-Friendly MSU Environmental Science and Policy Program Michigan State University East Lansing , Michigan Type: Program Education Level: Graduate Event Duration: Ongoing Philosophy of the doctoral specialization: In the ...
Background:Timely access to publicly funded health services is a priority issue across the healthcare continuum in Canada. The purpose of this study was to examine wait list management...Full Text Available
BackgroundHepatitis C virus (HCV) infection is the leading cause of chronic hepatitis which progresses to hepatocellular carcinoma (HCC) afflicting > 170 million people worldwide....Full Text Available
Since many years, people take care of hazardous consequences of a non controlled economic growth and the sustainable development concept gains on one. This situation leads to consequences in the building industry and in the energy policy: buildings insulation in consideration, demand of consultants. In this framework, the partnership between Gaz De France and CICF has to be built. (A.L.B.)
Radon in the home is the main source of exposure to ionising radiation for most people. In 1990 the National Radiological Protection Board issued revised advice to the United Kingdom Government on standards of protection against radon in the home. A description is offered of the survey work being undertaken by the Board which includes radiation measurements of thousands of homes in the United Kingdom. (author).
Neutrophils from people with poorly controlled diabetes present a primed phenotype and secrete excessive superoxide. Phospholipase A2 (PLA2)-derived arachidonic acid (AA)...Full Text Available
Convergenomics is about the megatrends that are shaping how people behave and organizations work. In this insightful analysis, Sang Lee and David Olson describe how globalization, digitization, changing demographics, changing industry mix, deregulation and privatization, commoditization of processes, new value chains, emerging new economies, deteriorating environment, and cultural conflicts have led to what they define as a convergence revolution.Lee and Olson discuss this convergence revolution from the perspectives of technology, industry, knowledge, open-source networking and bio-artificial
... I don't think the 5 categories are exclusive nor do they represent the universe of ways people best receive love and affection. The author addresses this last point somewhat by saying there are many dialects within the 5 languages. Some might view that as a cop out. My strongest complaint is that the language of the book is dumb downed to reach the lowest grade of reader. Like ...
In a recent survey of the stellar populations of LINERS and LINER/HII Transition Objects (TOs) we identified a numerous class of nuclei which stand out because of their conspicuous 10^8-9 yr populations. These objects were called ``Young-TOs'', since they all have TO-like emission line ratios. In this paper we investigate the radial variations of spectral properties in Low Luminosity AGN. Our analysis is based on high S/N, 3500-5500 A, long-slit spectra for 47 galaxies. The data probe distances of typically up to 850 pc from the nucleus with a resolution of ~ 100 pc and S/N ~ 30. Stellar population gradients are mapped by the radial profiles of absorption line equivalent widths and colours along the slit. These variations are further analyzed by means of a decomposition of each spectrum in terms of template galaxies representative of very young (<= 10^7 yr), intermediate age (10^8-9 yr) and old (10^10 yr) populations. Our main findings are: ...
The X-ray diffraction analysis of (U,Ce)O{sub 2} with the CeO{sub 2} contents ranging from 0 to 20 mol% CeO{sub 2} was performed at room temperature to obtain the variation in the lattice parameter with the CeO{sub 2} content. Ultrasonic pulse echo measurements were also carried out to estimate the change in the mechanical properties of (U,Ce)O{sub 2} with the CeO{sub 2} content. The lattice parameter of (U,Ce)O{sub 2} was found to decrease with increasing CeO{sub 2} content. The variation in the lattice parameter with the CeO{sub 2} content closely followed the Vegard law. The shear and longitudinal velocities in (U,Ce)O{sub 2} were found to decrease with increasing CeO{sub 2} content. The Young`s and shear moduli, and Poisson`s ratio estimated from the wave velocities decreased with the CeO{sub 2} content. No mechanical property showed anomaly in low CeO{sub 2} content region. (orig.).
We present the results of a monitoring campaign aimed at deriving rotation periods for a representative sample of stars in the young (30 Myr) open cluster IC 2602. Rotation periods were derived for 29 of 33 stars monitored. The periods derived range from 0.2d (one of the shortest known rotation periods of any single open cluster star) to about 10d (which is almost twice as long as the longest period previously known for a cluster of this age). We are able to confirm 8 previously known periods and derive 21 new ones, delineating the long period end of the distribution. Despite our sensitivity to longer periods, we do not detect any variables with periods longer than about 10d. The combination of these data with those for IC 2391, an almost identical cluster, leads to the following conclusions: 1) The fast rotators in a 30 Myr cluster are distributed across the entire 0.5 < B-V < 1.6 color range. 2) 6 stars in our sample are slow rotators, with periods longer ...
Continuous metallic glass ribbons were produced by mejans of liquid-quenching at rates >10/sup 50/C/s. The ribbons, typically 30 ..mu..m thick and 1 to 2 mm wide, were determined to be glassy by X-ray diffraction (XRD) employing CuK..cap alpha.. and MoK..cap alpha.. radiation. Mechanical properties of the as-quenched product were determined by measurements of hardness, tensile strength and Young's modulus. The Vicker's diamond pyramid microhardness (H/sub V/) was measured on epoxy mounted samples using a Lietz Miniload instrument with a 100 g load. Tensile tests were conducted in an Instron machine using specimens which were hand-polished to produce smooth, parallel sides. Young's modulus (E) is given by the relationship rho V/sub E/sup 2//. V/sub E/, the velocity of extensional mode waves, was measured by the pulse-echo technique using a Panametrics Intervalometer and glass density, rho, was obtained by the liquid ...
The effect of irradiation on the tensile properties of oil palm empty fruit bunch (OPEFB) fiber reinforced poly(vinyl chloride)/epoxidized natural rubber (PVC/ENR) blends were studied. The composites were prepared by mixing the fiber and the PVC/ENR blend using HAAKE Rheomixer at 150 deg. C. The composites were then irradiated by using a 3.0 MeV electron beam machine at doses ranging from 0 to 100 kGy in air and room temperature. The tensile strength, Young's modulus, elongation at break and gel fraction of the composites were measured. Comparative studies were also made by using poly(methyl acrylate) grafted OPEFB fiber in the similar blend system. An increase in tensile strength, Young's modulus and gel fraction, with a concurrent reduction in the elongation at break (Eb) of the PVC/ENR/OPEFB composites were observed upon electron beam irradiation. Studies revealed that grafting of the OPEFB fiber with methyl acrylate did ...
Context. We present a multi-wavelength, high-resolution observational survey of the young binary system Haro 6-10 (GV Tau, IRAS 04263+2426), which is harbouring one of the few known infrared companions. Aims. The primary goal of this project is to determine the physical and geometrical properties of the circumstellar and circumbinary material in the Haro 6-10 system. Methods. High-resolution optical (HST/WFPC2) and near-infrared (VLT/NACO) images in different bands were analysed to investigate the large-scale structures of the material around the binary.Mid-infrared interferometry (VLTI/MIDI) and spectroscopy (TIMMI2 at the 3.6m ESO telescope) were carried out to determine the structure and optical depth of the circumstellar material around the individual components. Results. The multi-wavelength observations suggest that both components of the binary system Haro 6-10 are embedded in a common envelope. The measured extinction indicates a dust composition of the ...
This paper presents diffraction-limited 1-18 micron images of the young quadruple star system HD 98800 obtained with the W. M. Keck 10-m telescopes using speckle and adaptive optics imaging at near-IR wavelengths and direct imaging at mid-IR wavelengths. The two components of the visual binary, A and B, both themselves spectroscopic binaries, were separable at all wavelengths, allowing us to determine their stellar and circumstellar properties. Combining these observations with spectroscopic data from the literature, we derive an age of 10 Myr, masses of 0.93 and 0.64 M_sun and an inclination angle of 58 deg for the spectroscopic components of HD 98800 B, and an age of 10 Myr and a mass of 1.1 M_sun for HD 98800 Aa. Our data confirm that the large mid-IR excess is entirely associated with HD 98800 B. This excess exhibits a black body temperature of 150 K and a strong 10 micron silicate emission feature. The theoretical equilibrium radius of large, perfectly ...
To determine MTRs for normal structures and benign diseases in the breast two-dimensional magnetization transfer imaging was performed in 62 patients and in 3 young female volunteers. With regard to the MTRs of measurements in the normal breast tissues, fat tissues which is close to simple cysts in MTRs show little transfer of longitudinal magnetization. MTRs of the muscles was 15.15{+-}6.22%, which exceeded those of breast parenchyma. The breast parenchyma didn`t show the change of MTR value due to the difference of patient age and due to variable amount of fat and fibrous tissues. Breast parenchyma in the two young volunteers clearly showed biphasic change of MTR values in accordance with the menstrual cycle; little transfer value was due to hydration in the postovulatory period and high transfer value was due to dehydration in the preovulatory period. In the remaining one volunteer during lactation period, mammary parenchyma shows sever ...
Through analysis of archival images and photometry from the Spitzer GLIMPSE and MIPSGAL surveys combined with Two Micron All Sky Survey and MSX data, we have identified 488 candidate young stellar objects (YSOs) in the giant molecular cloud M17 SWex, which extends #approx#50 pc southwest from the prominent Galactic H II region M17. Our sample includes >200 YSOs with masses >3 M _s_u_n that will become B-type stars on the main sequence. Extrapolating over the stellar initial mass function (IMF), we find that M17 SWex contains >1.3 x 10"4 young stars, representing a proto-OB association. The YSO mass function is significantly steeper than the Salpeter IMF, and early O stars are conspicuously absent from M17 SWex. Assuming M17 SWex will form an OB association with a Salpeter IMF, these results reveal the combined effects of (1) more rapid circumstellar disk evolution in more massive YSOs and (2) delayed onset of massive star formation.
Brine from active oil wells seeped through the soil of a forested site in north-western Pennsylvania and killed all vegetation in its path, leaving the affected area unproductive and unsightly. After the brine source was eliminated, herbaceous plants, shrubs and forest tree seedlings became established and developed rapidly. Establishment began in the first year and by Year 4 the site had developed into a healthy young forest. Results show that Allegheny hardwood forest sites damaged by brine water will rapidly revegetate once the brine water discharge is stopped if there is a seed supply and if the area is fenced to exclude deer. 3 figs., 12 refs.
The water culture experiment of Houttuynia cordata of the medicinal plant was carried out, and basic study on {sup 137}Cs accumulation characteristic and internal circulation in H. cordata in the fruiting stage was investigated since the flowering season. H. cordata accumulated 80% of {sup 137}Cs absorbed unlike K to the root, rhizome, terminal bud of the underground part for the rhizome reproduction. {sup 137}Cs content to the young leaf, spike, involucre increased in the flowering season. Thereafter, {sup 137}Cs was recirculated to the developing organs in second generations such as the rhizome and bud. (author)
Methods are described for the production of callus and subsequent shoot and root induction and multiplication using stamen filaments, nodes of young stems of mature trees or cotyledon petioles. A high frequency of contamination occurred using nodal sections from mature trees, whereas up to 100% sterility was obtained with cotyledons and stamens. The rooting % of shoot cultures from nodes or stamen callus was low compared with that of shoots from seedling callus. Considerable variation was observed between clones from different trees in their ability to produce shoots and roots. 27 references
Posttraumatic tibia valga is a well-recognized complication following fracture of the upper tibial metaphysis in young children. We present a case of a child who developed a valgus deformity following fracture of the proximal tibia and fibula in which quantitative bone scintigraphy at 5 months after injury demonstrated increased uptake at the proximal tibial growth plate with proportionally greater uptake on the medial side. This finding suggests that the valgus deformity in this patient was due to a relative increase in vascularity and consequent overgrowth of the medial portion of the proximal tibial physis.
Posttraumatic tibia valga is a well-recognized complication following fracture of the upper tibial metaphysis in young children. We present a case of a child who developed a valgus deformity following fracture of the proximal tibia and fibula in which quantitative bone scintigraphy at 5 months after injury demonstrated increased uptake at the proximal tibial growth plate with proportionally greater uptake on the medial side. This finding suggests that the valgus deformity in this patient was due to a relative increase in vascularity and consequent overgrowth of the medial portion of the proximal tibial physis.
Abstract in english Odontopus brevirostris (Hustache, 1936) feeding on Annona squamosa L., A. cherimola Mill., A. glabra L., and A. muricata L. was observed. The last three host plants are recorded for the first time. The endophitic oviposition occurs in the veins of the ventral surface of the young leaves. The larvae, leaf miners, eat the parenchyma and the adults make small holes in the leaves. The pupation occurs in spherical cocoons protected by a sort of nest (pupation chamber) between the two epidermal layers.
Measurements of the humeral cortical thickness demonstrate that generalised osteoporosis in female Bantu commences in the fifth decade and gradually increases until, in the ninth decade, all subjects are osteoporotic. The combined cortical thickness (CCT) of the humerus in young adults is very similar to that found previously in a white London population and the loss of cortex with age is very similar. It is concluded that the known low incidence of femoral neck fracture in Bantu is not due to a lower incidence of generalised osteoporosis but to environmental factors. The chief environmental factor postulated is the greater amount of physical work performed by the Bantu. A more careful mode of walking is suggested as a subsidiary cause. (orig.).
The effect of protein malnutrition on the metabolism of collagen in bone was studied in young female albino rats after a single injection of "3H-proline. Both specific and total radioactivities of hydroxyproline in the total collagen of the bone were found to decrease in the protein-deficient animals, indicating decreased rate of collagen synthesis. In the urine the amount of hydroxyproline excreted and total radioactivity of "3H-hydroxyproline were greatly decreased. The results of the present investigation therefore clearly indicate decreased synthesis and catabolism of collagen in bones of protein deficient animals compared to controls. (auth.).
We report here the imaging findings of a rare case of a lethal form of Gorham disease in a young female patient. Multimodality imaging findings over 13 year-follow-up demonstrated progressive wide spread skeletal and soft tissue abnormalities with permeative osteolysis, pathological fractures and severe skeletal deformities. Unusual extensive osseous and soft tissue pneumatosis was illustrated on cross-sectional studies. The progressive nature of this form of Gorham disease and the subsequent complications eventually culminated in patient's death. (orig.)
We report here the imaging findings of a rare case of a lethal form of Gorham disease in a young female patient. Multimodality imaging findings over 13 year-follow-up demonstrated progressive wide spread skeletal and soft tissue abnormalities with permeative osteolysis, pathological fractures and severe skeletal deformities. Unusual extensive osseous and soft tissue pneumatosis was illustrated on cross-sectional studies. The progressive nature of this form of Gorham disease and the subsequent complications eventually culminated in patient's death. (orig.)
We demonstrate the use of a variational method to determine a quantitative lower bound on the rate of convergence of Markov Chain Monte Carlo (MCMC) algorithms as a function of the target density and proposal density. The bound relies on approximating the second largest eigenvalue in the spectrum of the MCMC operator using a variational principle and the approach is applicable to problems with continuous state spaces. We apply the method to one dimensional examples with Gaussian and quartic target densities, and we contrast the performance of the basic Metropolis-Hastings algorithms with a ``smart'' variant that incorporates gradient information into the trial moves. We find that the variational method agrees quite closely with numerical simulations. We also see that the smart MCMC algorithm often fails to converge geometrically in the tails of the target density except in the simplest case we examine, and even then care must be taken to choose the appropriate ...
A magnetic rhombohedral PrCo_2C_x (x = 0.05 #approx#0.25) phase (space group Rbar 3m), which is heavily twinned along the #left brace#110#right brace# and #left brace#211#right brace# planes, was identified. The twinning mechanism was explored by analyzing the reduction of crystal symmetry due to the cubic-rhombohedral phase transformation. The origin of the twinning and the formation of four twin variants were attributed to the insertion of carbon interstitials into Co_4 tetrahedrons along the bar 3 axis in the rhombohedral lattice, which corresponds to one of the four equivalent axes of its parent PrCo_2 cubic-lattice.
The coal-fired combined cycle with partial gasification and fluidized bed combustion (PGFBC-CC), also referred to as a hybrid cycle, has advantages of staged energy conversion and utilization, which can attain high thermal efficiency with low emissions. Four kinds of PGFBC-CC are studied in this paper, two based on pressurized fluidized bed combustion (PFBC) and two on atmospheric fluidized bed combustion (AFBC). Thermal performance calculations and parametric analyses were performed. On the basis of the results, from the above analyses, the best integration system for China is suggested. In addition, a preliminary exergetic analysis is carried out for three of the PGFBC-CC variants.
Objective A number of effective treatments for bulimia nervosa have been developed, but they are infrequently used, in part due to problems with dissemination. The goal of this study was to examine the cost effectiveness of telemedicine delivery of cognitive behavioral therapy for bulimia nervosa. Method A randomized controlled trial of face-to-face versus telemedicine cognitive behavioral therapy for bulimia nervosa. One hundred twenty eight women with DSM-IV bulimia nervosa or eating disorder, not otherwise specified subsyndromal variants of bulimia nervosa were randomized to 20 sessions of treatment over 16 weeks. A cost effectiveness analysis from a societal perspective was conducted. Results The total cost per recovered (abstinent) subject was $9324.68 for face-to-face CBT, and $7300....
Many advances have been carried out on the estrogens, GnRH and endocannabinoid system that have impact in the reproductive field. Indeed, estrogens, the generally accepted female hormones, have performed an unsuspected role in male sexual functions thanks to studies on non-mammalian vertebrates. Similarly, these animal models have provided important contributions to the identification of several GnRH ligand and receptor variants and their possible involvement in sexual behavior and gonadal function regulation. Moreover, the use of non-mammalian animal models has contributed to a better comprehension about the endocannabinoid system action in several mammalian reproductive events. We wish to highlight here how non-mammalian vertebrate animal model research contributes to advancements with i...
The discovery that the cosmic expansion is accelerating has been followed by an intense theoretical and experimental response in physics and astronomy. The discovery implies that our most basic notions about how gravity work are violated on cosmological distance scales. One simple fix is the introduction of a cosmological constant into the field equations for general relativity. However, the extremely small value of the cosmological constant, relative to theoretical expectations, has led theorists to explore a wide variety of alternative explanations that involve the introduction of an exotic negative-pressure fluid or a modification of general relativity. Here we briefly review the evidence for cosmic acceleration. We then survey some of the theoretical attempts to account for it, including the cosmological constant, quintessence and its variants, mass-varying neutrinos, and modifications of general relativity, such as scalar-tensor and $f(R)$ theories and ...
A method is proposed for evaluating reliability of planning and calculation of the reliability factor with current planning of open pit mining operations. For a quantitative evaluation of the reliability of fulfilling the planned assignment, laws were defined for distribution of the quality characteristics of the coal. After establishing that coal ash content follows the normal distribution law, the probability was defined that the actual output of coal is greater or equal to the planned. Calculation of the factor of reliability of the current planning of open mining operations makes it possible to determine the optimum planning for this period and the probability of fulfillment of the planned assignments. The technique of planning with regard for reliability makes it possible to select the most reliable variant of the plan within the planning period.
Contradictory reports in the literature on the reliability of lymphography stimulated the authors to test the diagnostic accuracy, employing methods which are approximately analogous to practice, using carcinoma of the cervix as the model on which the study was carried out. Using 21 observers it was found that there was no correlation between their experience and on-target accuracy of the diagnosis. Good observers obtained an accuracy of 85% with good proportions between sensitivity in the recognition of detail, specificity and readiness to arrive at a decision on the basis of discriminatory ability. With the help of the concept of the ROC curves, the position taken up by the observers in respect of diagnostic decisions, and a complex manner of assessing the various characteristic factors determining diagnostic accuracy, are demonstrated. This form of test, which permits manipulation of different variants of diagnosis, is recommended, among other things, for ...
November 1989, marked the beginning of a new three-year cycle of DOE grant support, in connection with which the program underwent a major reorganization. This document presents the progress on the three objectives of the present program which are: to isolate by the technique of two-dimensional polyacrylamide gel electrophoresis (2-D PAGE), proteins of special interest because of the relative mutability of the corresponding gene, establish the identity of the protein, and, for selected proteins, move to a characterization of the corresponding gene; to develop a more efficient approach, based on 2-D PAGE, for the detection of variants in DNA, with special reference to the identification of mutations in the parents of the individual whose DNA is being examined; and, to continue an effective interface with the genetic studies on the children of atomic bomb survivors in Japan, with reference to both the planning and implementation of new studies at the molecular level.
Recently, molecular clusters are the subject of several experimental and computational studies by means of their bonding structures. We studied, first time, small difluorine monoxide clusters such as dimer (linear, cyclic, bifurcated), trimer and tetramer structures using B3LYP variant of density functional theory with cc-pVDZ basis set. On the basis of the optimized geometry, various energy properties such as binding energy, molecular orbital energies, two and three body interaction energies have been calculated. Additionally dipole moment, polarizability, anisotropic polarizability and hyper polarizability have been calculated and compared with monomer structure.
We have demonstrated that, with simple pH adjustment, volatile drugs such as methamphetamine, amphetamine, 3,4-methylenedioxymethamphetamine (MDMA), ketamine, and valproic acid could be analyzed rapidly from raw biofluid samples (e.g. urine and serum) without dilution, or extraction, using atmospheric pressure ionization. The ion source was a variant type of atmospheric pressure chemical ionization (APCI) that used a dielectric barrier discharge (DBD) to generate the metastable helium gas and reagent ions. The sample solution was loaded in a disposable glass pipette, and the volatile compounds were purged by nitrogen gas to be reacted with the metastable helium gas. The electrodes of the DBD were arranged in such a way that the generated glow discharge was confined within the discharge tub...
A kind of metastable beta titanium alloy, i.e. Ti-10Mo-8V-1Fe-3.5Al, was aged under elastic compressive stress. Transmission electron microscopy (TEM) investigations revealed that, in the stress-aged samples, precipitated alpha plates were parallel to each other. However, in the conventionally aged samples, alpha plates intersected each other. In other words, variant of alpha plate was selected in the stress-aged samples. Tensile tests showed that, at equivalent tensile strength, the stress-aged samples exhibited higher ductility, compared to the conventionally aged ones.
Methods of automated control of 18-10-type steel inclination to IGC are developed and a corresponding automated testing complex (ATS) is created. 08Kh18N10T steel samples had two variants of thermal treatment: 1) 1200 deg (5 h), 600 deg (50 h); 2) 1200 deg (5 h). Methods of non-destructive automated control of 18-10-type steel inclination to IGC are developed on the basis of potentiodynamic reactivation (PR) principle. Automated testing complex is developed, which has undergone experimental running and demonstrated a high confidence of results, reliability and easy operation.
Dissolved microcystins (MCs) are regularly present in water dominated by microcystin-producing, bloom-forming cyanobacteria. In vitro experiments with environmentally feasible concentrations (5 ? 10?7 M) of the three most common microcystins, MC-LR, MC-RR, and MC-YR, revealed that they influence the metabolism of different representative phytoplanktons. At light intensities that are close to the cyanobacterial bloom environment (50??mol m?2 s?1), they produce morphological and physiological changes in both microcystin-producing and -nonproducing Microcystis aeruginosa strains and also have similar effects on the green alga Scenedesmus quadricauda that is frequently present in cyanobacterial blooms. All three microcystin variants tested induce cell aggregation, increase in cell volume, and ...
In this report we present a suite of subroutines for the solution of sparse unsymmetric sets of linear equations using a variant of Gaussian elimination. The subroutines are divided into three distinct phases. The first phase optionally preorders the matrix to block triangular form and then performs a sparsity oriented factorization, the second factorizes a matrix of a similar sparsity pattern, while the third uses these decompositions to solve the equations. In this revised edition, the actual Fortran listings have been replaced by a reference to their availability in machine readable form. Other changes to the first edition are minor. This revision is essentially a reprint of the 1979 revision, the only changes being that the MA28A specification sheet has been typeset and has a few minor changes and the existence of a version of the package for complex equations is announced. 11 refs., 11 tabs.
In the post Genome era, the aim of behavior genetics has shifted from estimating the relative contributions of genes and environmental factors to (co-)variation in human complex traits, to localization of genes and identification of functional genetic variants. This special issue reflects this transition and presents fifteen papers that report on genome-wide linkage scans for complex traits in humans and on methodological tools and innovations. Six papers focus on cognition and report overlapping linkage peaks on chromosomes 6p and 14p. Papers on addictive behavior, i.e. smoking and alcohol dependence and its endophenotypes, find moderate LOD scores on chromosomes 6p, 5q, 4p and 7q, respectively. Three papers concentrate on emotionality, depression and loneliness and examine chromosomes 2q...
Abstract Introduction: Laparoscopic subtotal adrenalectomy (LSA) has emerged as a treatment option in the management of certain adrenal pathologies. After LSA, a satisfactory blood supply to the adrenal remnant is vital to preserve steroid function. The aim of this study was to review the adrenal blood supply with relevance to LSA. Materials and Methods: The adrenal blood supply was examined in three ways: 1) a review of six previous cadaver studies looking at adrenal blood supply; 2) a review of our 164 consecutive laparoscopic adrenalectomies (LAs) (January 1999?January 2009); the details of the main adrenal veins and variants had been prospectively recorded; and 3) dissection of 4 cadaver specimens (macroscopic and histologic examination was performed). Results: The six cadaver studies ...
A well-known diffuse interface model consists of the Navier-Stokes equations nonlinearly coupled with a convective Cahn-Hilliard type equation. This system describes the evolution of an incompressible isothermal mixture of binary-fluids and it has been investigated by many authors. Here we consider a variant of this model where the standard Cahn-Hilliard equation is replaced by its nonlocal version. More precisely, the gradient term in the free energy functional is replaced by a spatial con- volution operator acting on the order parameter phi. Therefore the coupling with the Navier-Stokes equations is difficult to handle even in two spatial dimensions because of the lack of regularity of phi. We establish the global existence of a weak solution.
Meningococcal disease is an infection caused by Neisseria meningitidis. Genetic factors contribute to host susceptibility and progression to disease, but the genes responsible for disease development are largely unknown. We report here a genome-wide association study for host susceptibility to meningococcal disease using 475 individuals with meningococcal disease (cases) and 4,703 population controls from the UK. We performed, in Western European and South European cohorts (consisting of 968 cases and 1,376 controls), two replication studies for the most significant SNPs. A cluster of complement factor SNPs replicated independently in both cohorts, including SNPs within complement factor H (CFH) (rs1065489 (p.936D
Occurrence of genetic variants during micropropagation is occasionally encountered when the cultures are maintained in vitro for long period. Therefore, the micropropagated multiple shoots of Vanilla planifolia Andrews developed from axillary bud explants established 10 years ago were used to determine somaclonal variation using random amplified polymorphic DNA (RAPD) and intersimple sequence repeats markers (ISSR). One thousand micro-plants were established in soil of which 95 plantlets (consisting of four phenotypes) along with the mother plant were subjected to genetic analyses using RAPD and ISSR markers. Out of the 45 RAPD and 20 ISSR primers screened, 30 RAPD and 7 ISSR primers showed 317 clear, distinct and reproducible band classes resulting in a total of 30 115 bands. However, no ...
Glial fibrillary acidic protein (GFAP) is the main intermediate filament protein in mature astrocytes, but also an important component of the cytoskeleton in astrocytes during development. Major recent developments in astrocyte biology and the discovery of novel intermediate filament functions enticed the interest in the function of GFAP. The discovery of various GFAP splice variants gave an additional boost to explore this protein in more detail.The structural role of GFAP in astrocytes has been widely accepted for a long time, but over the years, GFAP has been shown to be involved in astrocyte functions, which are important during regeneration, synaptic plasticity and reactive gliosis. Moreover, different subpopulations of astrocytes have been identified, which are likely to have distinc...
Introduction: The orofacial clefts include 30 variant according to Tessier classification: the number 30 contain mandibular arc damage isolated or associated with damage of surrounding soft tissue. Case report: Our patient was a newborn with median mandibular cleft associated with ankyloglossia, bifid tongue and a top cervical fistula. We have not found polymalformative syndrome. The early surgical management included one time and after-effect were simple within 11months. Discussion: We point up difficulties for antenatal diagnosis and controversy about appropriate time for management of bone defect. The last physiopathologic hypotheses were explicated.
The previous decade has brought a remarkable increase of the interest in applications that deal with querying and mining of time series data. Many of the research efforts in this context have focused on introducing new representation methods for dimensionality reduction or novel similarity measures for the underlying data. In the vast majority of cases, each individual work introducing a particular method has made specific claims and, aside from the occasional theoretical justifications, provided quantitative experimental observations. However, for the most part, the comparative aspects of these experiments were too narrowly focused on demonstrating the benefits of the proposed methods over some of the previously introduced ones. In order to provide a comprehensive validation, we conducted an extensive experimental study re-implementing eight different time series representations and nine similarity measures and their variants, and testing their effectiveness on ...
The transformation mechanism of hexagonal delta phase from the disordered bcc gamma phase has not been reported before in the Zr-rich U-Zr alloy system. With the help of X-ray diffraction, transmission electron microscopy (TEM) and high-resolution TEM analyses it was shown that the gamma to delta conversion takes place by the lattice collapse mechanism of omega transformation. It was also ascertained that a higher aging temperature or time promotes the growth of all four variants of the delta phase within a parent gamma grain. In addition, ab initio electronic structure calculations showed that the bcc to hexagonal transformation, involving partial ordering of the parent bcc phase followed by (111) plane collapse, is energetically favorable.
In eukaryotes, accurate chromosome segregation during mitosis and meiosis is coordinated by kinetochores, which are unique chromosomal sites for microtubule attachment. Centromeres specify the kinetochore formation sites on individual chromosomes, and are epigenetically marked by the assembly of nucleosomes containing the centromere-specific histone H3 variant, CENP-A. Although the underlying mechanism is unclear, centromere inheritance is probably dictated by the architecture of the centromeric nucleosome. Here we report the crystal structure of the human centromeric nucleosome containing CENP-A and its cognate ?-satellite DNA derivative (147 base pairs). In the human CENP-A nucleosome, the DNA is wrapped around the histone octamer, consisting of two each of histones H2A, H2B, H4 and CENP...
Whereas in part 1 and 2 the detailed observation equations of terrestrial type for an integrated geodetic model are presented this paper will outline how the theory is transferred in an operational program. The main lines of functions of the FORTRAN IV program are discussed. Since the input specifications as well as the data requirements are described in detail and illustrated by example of input and output part 3 can serve as an user-guide for OPERA. OPERA is an acronym for operational adjustment. Besides the integrated determination of 3D-geocentric coordinates and the gravity disturbing potential the program can handle all cases of traditional geodesy (in total 13 variants of solution are provided) equivalent also with adjustments in ellipsoidal coordinates B, L or H, as well as constrained adjustments, pure prediction of the gravity disturbing field, etc.
Starting from the generalized Konishi anomaly equations at the non-perturbative level, we demonstrate that the algebraic consistency of the quantum chiral ring of the N=1 super Yang-Mills theory with gauge group U(N), one adjoint chiral superfield X and N_f<=2N flavours of quarks implies that the periods of the meromorphic one-form Tr dz/(z-X) must be quantized. This shows in particular that identities in the open string description of the theory, that follow from the fact that gauge invariant observables are expressed in terms of gauge variant building blocks, are mapped onto non-trivial dynamical equations in the closed string description.
We describe a large class of chemical reaction networks, those endowed with a subtle structural property called concordance. We show that the class of concordant networks coincides precisely with the class of networks which, when taken with any weakly monotonic kinetics, invariably give rise to kinetic systems that are injective --- a quality that, among other things, precludes the possibility of switch-like transitions between distinct positive steady states. We also provide persistence characteristics of concordant networks, instability implications of discordance, and consequences of stronger variants of concordance. Some of our results are in the spirit of recent ones by Banaji and Craciun, but here we do not require that every species suffer a degradation reaction. This is especially important in studying biochemical networks, for which it is rare to have all species degrade.
We report about the fabrication and analysis of the properties of Cr/CrO_x/Cr tunnel junctions and SET transistors, prepared by different variants of direct-writing multilayer technique. In all cases, the CrO_x tunnel barriers were formed in air under ambient conditions. From the experiments on single junctions, values for the effective barrier height and thickness were derived. For the Cr/CrO_x/Cr SET transistors we achieved minimal junction areas of 17 x 60 nm^2 using a scanning transmission electron microscope for the e-beam exposure on Si_3N_4 membrane substrate. We discuss the electrical performance of the transistor samples as well as their noise behavior.
Abstract Sudden infant death syndrome (SIDS) is always a devastating and unexpected occurrence. SIDS is the leading cause of death in the first 6 months after birth in the industrialized world. Since the discovery in 1998 of long QT syndrome as an underlying substrate for SIDS, around 10-20% of SIDS cases have been proposed as being caused by genetic variants in either ion channel or ion channel-associated proteins. Until now, 10 cardiac channelopathy susceptibility genes have been found to be implicated in the pathogenesis of SIDS. Four of the genes encode cardiac ion channel a-subunits, 3 genes encode ion channel b-subunits, and 3 genes encode other channel-interacting proteins. All 10 genes have been associated with primary electrical heart diseases. SIDS may hereby be the initial sympt...
The alloy type 'alloy 800' with its different variants is used for numerous components in high-temperature reactor (HTR) plants, e.g. for hot-gas conductors, the high-pressure part of steam generators, superheaters, steam collecting vessels and live steam conductors. This study deals with the evaluation of creep rupture tests on 28 welded joints of alloy 800 with an accumulated test duration of 410 years, with the objective to obtain quantitative information on a possible loss of strength in comparison with the unwelded material. The longest test period of an individual test amounted to 98,000 h and the analyzed test temperature range lay between 550"0 and 1000"0C. (orig./MM).
Techniques of chemical analysis, amino acid sequencing and autoradiography are being used to study the frequency of incorporation of normally noncoded amino acids into hemoglobins and seminal fluid proteins. We are studying, by the sequencing of radiolabeled proteins followed by the recovery of ["3H] isoleucine phenylthiohydantoin by high-performance liquid chromatography, the frequency at which normally noncoded isoleucine is incorporated into hemoglobin because of base-substitution mutations versus translational errors. Irradiation increases the isoleucine content of human hemoglobin and the frequency of substitution of isoleucine for specific amino acids in rabbit hemoglobin. Studies to date indicate that these techniques have been developed sufficiently for initial analysis of the potential of drugs and environmental pollutants to induce base-substitution mutations in mammalian somatic cells.
A new evaluation of the 1% time strain limit for creep strength and the isochronous stress/strain relationship was to be undertaken for the type 800 alloy, based on up to date experimental data. After the evaluation of the 1% time strain limit curves and time fracture curves of individual melts, multilinear regression analyses were made to clear up the relationship between parameters of the creep behaviour such as creep strength, 1% time strain limit and time fracture strain on the one hand and metallurgical parameters such as C, Ti, Al, Ni, Cr contents or grain size and type of manufacture, on the other hand. Based on the knowledge gained from these calculations, new limits were determined for HTR material specifications for variants of the 800 alloy of the Rk, NT, DE, and HT type. (orig./DG).
In view of the importance of the material Alloy 800 in high-temperature reactor plants (HTR), a material data bank was established which is used for statistical evaluation of mechanical and physical material behaviour. Based on investigations on the interconnection between the mechanical properties at high temperatures and the metallurgical parameters, different types of Alloy 800 were specified in compliance with the component requirements. In addition, aspects of corrosion and toughness behaviour were taken into consideration. The specifications and strength characteristics for the different variants of Alloy 800 were incorporated into draft DIN standards after discussion and approval in expert committees. Further important characteristics of the mechanical and physical material behaviour were summarized in HTR material data sheets so as to furnish an improved basis for the design and stress analyses of Alloy 800 components. (orig.).
In view of the importance of the material Alloy 800 in high-temperature reactor plants (HTR), a material data bank was established which is used for statistical evaluation of mechanical and physical material behaviour. Based on investigations on the interconnection between the mechanical properties at high temperatures and the metallurgical parameters, different types of Alloy 800 were specified in compliance with the component requirements. In addition, aspects of corrosion and toughness behaviour were taken into consideration. The specifications and strength characteristics for the different variants of Alloy 800 were incorporated into draft DIN standards after discussion and approval in expert committees. Further important characteristics of the mechanical and physical material behaviour were summarized in HTR material data sheets so as to furnish an improved basis for the design and stress analyses of Alloy 800 components. (orig.).
We propose a combined experimental (Atomic Force Microscopy) and theoretical study of the structural and dynamical properties of nucleosomes. In contrast to biochemical approaches, this method allows to determine simultaneously the DNA complexed length distribution and nucleosome position in various contexts. First, we show that differences in the nucleo-proteic structure observed between conventional H2A and H2A.Bbd variant nucleosomes induce quantitative changes in the in the length distribution of DNA complexed with histones. Then, the sliding action of remodeling complex SWI/SNF is characterized through the evolution of the nucleosome position and wrapped DNA length mapping. Using a linear energetic model for the distribution of DNA complexed length, we extract the net wrapping energy of DNA onto the histone octamer, and compare it to previous studies.
This paper gives a concise overview of evolutionary algorithms for multiobjective optimization. A substantial number of evolutionary computation methods for multiobjective problem solving has been proposed so far, and an attempt of unifying existing approaches is here presented. Based on a fine-grained decomposition and following the main issues of fitness assignment, diversity preservation and elitism, a conceptual global model is proposed and is validated by regarding a number of state-of-the-art algorithms as simple variants of the same structure. The presented model is then incorporated into a general-purpose software framework dedicated to the design and the implementation of evolutionary multiobjective optimization techniques: ParadisEO-MOEO. This package has proven its validity and flexibility by enabling the resolution of many real-world and hard multiobjective optimization problems.
The paper describes two schemes that follow the model of Lamarckian evolution and combine differential evolution (DE), which is a population-based stochastic global search method, with the local optimization algorithm of conjugate gradients (CG). In the first, each offspring is fine-tuned by CG before competing with their parents. In the other CG is used to improve both parents and offspring in a manner that is completely seamless for individuals that survive more than one generation. Experiments involved training weights of feed-forward neural networks to solve three synthetic and four real-life problems. In six out of seven cases the DE?CG hybrid, which preserves and uses information on each solution?s local optimization process, outperformed two recent variants of DE.
Thirty-two asthmatic volunteers 8 to 16 yr of age, recruited through local schools and private physicians, were exposed in a chamber to clean air (control condition) and to sulfuric acid aerosol at a low concentration (46 +/- 11 micrograms/m3; mean +/- SD) and at a high concentration (127 +/- 21 micrograms/m3). Acid aerosols had mass median aerodynamic diameters near 0.5 microns with geometric standard deviations near 1.9. Temperature was 21 degrees C, and relative humidity was near 50%. Subjects were exposed with unencumbered oronasal breathing for 30 min at rest plus 10 min at moderate exercise (ventilation rate approximately 20 L/min/m2 of body surface). A subgroup (21 subjects) were exposed similarly to clean air and to high acid (134 +/- 20 micrograms/m3) with 100% oral breathing. Increased symptoms and bronchoconstriction were found after exercise under all exposure conditions. For the group, symptom and lung function responses were not statistically different during control and ...
The autors examined the hypothesis that current recommendations on dietary energy requirements may underestimate the total energy needs of young adult men, by measuring total energy expenditure (TEE) and resting energy expenditure (REE) in 14 weight-maintaining healthy subjects leading unrestricted lives. TEE and body composition were measured by using 2H(2)18O, and REE was measured by using indirect calorimetry. All subjects had sedentary full-time occupations and participated in strenuous leisure activities for 34 #+-# 6 (SE) min/d. TEE and REE were 14.61 #+-# 0.76 and 7.39 #+-# 0.26 MJ/d, respectively, and 202 #+-# 2 and 122 #+-# 2 kJ.kg-1.d-1. There were significant relationships between TEE and both body fat-free mass (r = 0.732, P less than 0.005) and measured REE (r = 0.568, P less than 0.05). Measured TEE:REE values were significantly higher than the recommended energy requirement (1.98 #+-# 0.09, compared with 1.55 or 1.67, P less than 0.005). These ...
In 1978 the Marshall Islands Radiological Safety Program was organized to perform radiation measurements and assess radiation doses for the people of the Bikini, Enewetak, Rongelap and Utirik Atolls. One of the major field components of this program is whole- body counting (WBC). WBC is used to monitor the quantity of gamma- emitting radionuclides present in individuals. A primary objective of the program was to establish {sup 137}Cesium body contents among the Enewetak, Rongelap and Utirik populations. {sup 137}Cs was the only gamma-emitting fission radionuclide detected in the 1,967 persons monitored. {sup 137}Cs body burdens tended to increase with age for both sexes, and were higher in males. The average {sup 137}Cs dose Annual Effective Dose for the three populations was as follows: For Enewetak, the dose was 22{+-}4 {mu}Sv. For Utirik, the dose was 33{+-} 3 {mu}Sv. Since 1985 the Rongelap people have been self-exiled to Mejatto. ...
The Thai-Canadian Nuclear Human Resources Development Linkage Project (the ''Project'') was initiated in 1994 in order to develop the engineering and scientific expertise needed for Thailand to decide whether and how the country can best benefit from the establishment of a nuclear power program. The Project was designed to upgrade current academics and people in industry, and to develop an adequate supply of new technical personnel for academic, industry, utility, regulatory and other government institutions. The key Project objectives included the establishment of a Chair in Nuclear Engineering at Chulalongkorn University, the upgrading of the current Masters level curriculum, the establishment of undergraduate and doctorate level curricula, development and delivery of an industrial training program for people in industry and government, exchanges of Thai and Canadian academics and industry experts to ...
Rapid growth in economic development, coupled with the absence of an electric grid in large areas of the rural countryside, have created a need for new energy sources both in urban centers and rural areas in China. Environmental pollution from the increased use of coal-fired steam turbines to meet this capacity expansion is a concern. There is a growing interest in China to develop renewable-energy resources and technologies to meet energy demands and help mitigate pollution problems. In February 1995, Secretary Hazel O`Leary of the U.S. Department of Energy signed an Energy Efficiency and Renewable Energy Protocol Agreement with the Chinese State Science and Technology Commission in Beijing, China. Under this agreement, projects using photovoltaics for rural electrification are being conducted in Gansu Province in western China and Inner Mongolia in northern China, providing the basis for much wider deployment and use of photovoltaics for meeting the growing rural energy demands of ...
Skin sensitization is the most commonly reported occupational illness, causing much suffering to a wide range of people. Identification and labeling of environmental allergens is urgently required to protect people from skin sensitization. The guinea pig maximization test (GPMT) and murine local lymph node assay (LLNA) are the two most important in vivo models for identification of skin sensitizers. In order to reduce the number of animal tests, quantitative structure-activity relationships (QSARs) are strongly encouraged in the assessment of skin sensitization of chemicals. This paper has investigated the skin sensitization potential of 162 compounds with LLNA results and 92 compounds with GPMT results using a support vector machine. A particle swarm optimization algorithm was implemented for feature selection from a large number of molecular descriptors calculated by Dragon. For the LLNA data set, the classification accuracies are 95.37% and ...
There are many sources of population exposures to power-frequency (50/60 Hz) electric and magnetic fields including household appliances and wiring, neighborhood distribution circuits, and high-voltage transmission lines. Bioeffects studies were unable to demonstrate that exposures to power-frequency fields can affect public health. Researcher have likewise been unable to show that the health effects of such exposures are negligible. State and federal regulatory agencies are, therefore, grappling with questions of whether and how to regulate the sitting or design of new extra high-voltage transmission lines so as to control the ground-level fields to which people are exposed. The purpose of this dissertation is to illuminate some of the exposure-related aspects of these question. A taxonomy of the relationship between field encounter and effect is developed to clarify the meaning of terms such as exposure and dose in the power-frequency context. The major inputs to ...
This paper use data from a pilot study to analyse relationships between type of resettlement (voluntary or involuntary) and individuals' everyday feelings, perceptions of risk, health status and control. The data were collected in 1995, within the Joint Study Project 2, i.e., a collaborative research project of the European Union and the Commonwealth of Independent States of Russia, Ukraine and Belarus, 1991/92 - 95/96. The aim of the study was to investigate reactions to change and new life conditions of people who had been resettled due to the Chernobyl accident. Participants from the respective countries included adult individuals sampled from two age groups of less than 45 years and 45 years and older, with approximately the same number of men and women. The questionnaire presented various topics to which responses were indicated on quantitative response scales, as well as in open ended response formats. The results presented here focus on emotional reactions, ...
Use of hydrogen in large scale applications is more usual than public is mentioning normally. Nevertheless reserve against hydrogen can be observed up to highest level decision-makers. Possibly a main reason can be found and eliminated by fixing: Some spectacular accidents happened in the past and found great interest. The publication of impressive accidents and the follow up of the events course was very carefully. The research in finding causalities in former decisions and follow up was not in the interest of some people or institutions. Important facts are even not noticed by insiders, but would have been very important for future decision makings and public acceptance of new applications. It will be demonstrated in three historical examples. Much more examples would be available and each one could help to find new applications for a saver and effective use of hydrogen in power supply. Awaking from new reserves could be avoided. Additional a safer handling would ...
SummaryIntended Outputs: Documentation demonstrating an improved biophysical understanding of the role of forests on low flows in the arid zone regions of India through the development and outputs from hydrological models such as Hyluc and SWAT.A documented analysis of the impacts on the poor of historical and current water management policies, including the investigation through PRA techniques of people's perceptions and beliefs of land-use/hydrological interactions, and the implications o [continued...]ObjectivesTo establish a better understanding of forest impacts on low flows and the social impact of water resources management in arid zone regions of India, and to develop tools which allow this improved understanding to be disseminated directly to stakeholders.DescriptionProject Background: Reducing river flows and groundwater tables, especially during the dry season, constitutes a major problem causing great hardship to large numbers of rural and urban poor ...
Muscular fatigue in the training athlete or military recruit has been hypothesized to cause increased bone strain that may contribute to the development of a stress fracture. Under normal circumstances, muscles exert a protective effect by contracting to reduce bending strains on cortical bone surfaces. In vivo strain studies in dogs show that muscle fatigue following strenuous exercise elevates bone strain and changes strain distribution. However, a similar experiment has yet to be performed in humans. The purpose of this work was to test the hypothesis in humans that strenuous fatiguing exercise causes an elevation in bone strain. It was also hypothesized that this elevation is greater in younger people than in older people due to the decline in muscle strength and endurance that normally occurs with age. To test these hypotheses, strain in the tibiae of seven human volunteers was measured during walking before and after a period of fatiguing ...
Human resource competence building and continued enhancement of performance is the most vital input for safe and reliable operations of a Nuclear Power Plant. Integrated planning leading to the decision of timely selection of optimum number of fresh people and deployment of experienced manpower with desired lead time is inevitable to achieve the above objective. For safe and reliable plant operation human performance analysis followed by suggestive measures to improve the same is needed. Corrective or strengthening input may be in terms of training, work environment, motivations, organizational culture and climate, leadership and prevailing environmental force and bio-rhythm of individuals with critical days are to be worked out The adequacy in training and development not only gives safe and reliable plant operations but results in greater employee satisfaction and self esteem as well. As of date, in the present vibrant global scenario, only the organization which ...
Not long ago primary census data became available to publicity. It opened qualitatively new perspectives not only for researchers in demography and sociology, but also for those people, who somehow face processes occurring in society. In this paper authors propose using Data Mining methods for searching hidden patterns in census data. A novel clustering-based technique is described as well. It allows determining factors which influence people behavior, in particular decision-making process (as an example, a decision whether to have a baby or not). Proposed technique is based on clustering a set of respondents, for whom a certain event have already happened (for instance, a baby was born), and discovering clusters' prototypes from a set of respondents, for whom this event hasn't occurred yet. By means of analyzing clusters' and their prototypes' characteristics it is possible to identify which factors influence the decision-making process. ...
Prejudice against overweight people is rife. However, there is a paucity of research on the underlying reasons for it. In two studies the relationship between body image, the tendency to make physical appearance-related comparisons (PACS), and both explicit and implicit anti-fat attitudes was examined. In Study 1 (n = 227) people with a high tendency to make physical appearance-related comparisons (high PACS scorers) reported lower self-appearance evaluation, but higher appearance orientation and explicit anti-fat attitudes. The PACS fully mediated the relationship between appearance orientation and explicit anti-fat attitudes. Study 2 (n = 134) found that the PACS also mediated the relationship between appearance orientation and implicit anti-fat attitudes. Thus, individual differences in factors such as body image and the tendency to make appearance-related comparisons, appear to play a central role in both explicit and implicit anti-fat ...
Examination of measurement invariance provides a powerful method to evaluate the hypothesis that the same set of psychological constructs underlies a set of test scores in different populations. If measurement invariance is observed, then the same psychological meaning can be ascribed to scores in both populations. In this study, the measurement model including core and supplementary subtests of the Wechsler Adult Intelligence Scale-Fourth edition (WAIS-IV) were compared across the U.S. and Canadian standardization samples. Populations were compared on the 15 subtest version of the test in people aged 70 and younger and on the 12 subtest version in people aged 70 or older. Results indicated that a slightly modified version of the four-factor model reported in the WAIS-IV technical manual provided the best fit in both populations and in both age groups. The null hypothesis of measurement invariance across populations was not rejected, and the ...
As radiation detection in the interest of national security becomes increasingly commonplace, inevitable questions arise concerning the interpretation of data from handheld radioisotope identifiers (RIIDs). Field elements typically require fast answers to provide an effective defense and to minimize the impact on legitimate movement of people and goods. To support this need, on-call experts at Sandia, Los Alamos, and Lawrence Livermore national laboratories cooperate in resolving radiation alarms rapidly and accurately. We present an overview, describe the work in progress to improve capabilities, and report on some of the lessons learned.
Abstract Charity is deeply embedded in the religious thought and teachings of the three monotheistic religions. This article, while focusing on medieval Islam, is set in a wider framework with references to both Jewish and Christian parallels. Three main topics are examined: the religious meaning of charity, the social and political ramifications of almsgiving, and the impact of the institutional form of charity (the pious endowment system, waqf pl. awqaf) on Muslim medieval society. In the course of this examination, the article deals with the motives and attitudes of the donors (mainly people of the ruling class and the wealthy) and with the recipients of charity (the poor as well as the learned class). The article equally provides an overview of the charitable institutions and functions...
... Thursday: South Brisbane Sailing Club, Orleigh Park Hill End Terrace, West End. Friday: Booroodabin Bowls Club, 126 Breakfast Creek Road, Newstead. Related Photos Ros Capeness and Jeff Shearin: six months on (Emma Sykes - ABC Local) Map Fig Tree Pocket 4069 Subscribe/RSS Subscribe to ABC Brisbane videos Subscribe to all ABC Local videos Topics: floods, people Locations: brisbane-4000,...
The origin of life is a long-standing mystery puzzling many people. This mystery possesses not only philosophical but also important biological significance. To unveil this mystery, the searches for the root of life, or the last universal common ancestor (LUCA), based on comparative-genomic analysis have been intensively performed on rRNAs, tRNAs and proteins sequences. The current search pointed to a Methanopyrus-proximal LUCA, which opens up the reconstruction of Lucan biology and helps to delineate the evolutionary pathways.
Over the years, nurses, doctors and scientists have sought ways of assessing the impact of pain on patients. While many of the instruments devised have been extremely useful in identifying the nature and intensity of pain, defining the effect it has on people's lives and perceptions has proved much more problematic. Based on the work she carried out with patients suffering from chronic benign pain, Karen Rose explores one aspect of these effects--the feeling of isolation. By using a four-step anthropological approach to identify the impact of pain, she argues, nurses can arrive at a realistic and accurate assessment of how patients are coping. PMID:7947167
This paper discusses key methods for sustaining quality engineering data, the fundamental principles that these methods are based on, and the methods for supporting the performance of nuclear power plants by the provision of quality engineering data at all times. The concept of an 'engineering data foundation', and a Configuration Management data model are developed. The concepts and methods for managing the integrity of engineering data across many different databases and document systems are developed, including the key concepts of data-positions and data-values, Master Data and Copy Data, and the concept of a 'partnership between people and technology'. (author). 7 refs., 1 tab., 2 figs.
Malnutrition?in the form of insufficient energy intakes?affects millions of people worldwide and the negative impact of this kind of hunger is well acknowledged, not least by agronomists trying to increase yields to ensure a sufficient supply of food. This review focuses on another, more particular and ?hidden? form of malnutrition, namely mineral malnutrition. It illustrates the burden of disease that is caused by mineral deficiencies and the social and economic consequences they bring about. Mineral malnutrition has a considerable negative impact on individual well-being, social welfare and economic productivity. Agricultural scientists should keep the nutritional qualities of food in mind and?next to optimizing the agricultural properties of crops that are paramount for their adoption b...
Purpose - The article shares insights from a program that was developed to address burnout, compassion fatigue and vicarious trauma. The program works from the premise that people and organizations thrive when they have shared values and common understandings. Design/methodology/approach - The approach draws together reflection at the organizational and person levels. Connecting business ethics and organizational analysis, improving understanding of the body's energy as well as inter-cultural understanding are all achievable while adopting the resilience development methods. Findings - The article concludes that reflective practice through the tools used on the program enhances understanding of the challenges faced by organizations and the individuals involved. It provides creative routes ...
Objective: To estimate exposure dose of personnel around patients by Monte Carlo method and integration method. Methods: Exposures were estimated by a Monte Carlo practical program with Visual Basic 6.0 and integration method using 'pen-and-paper'. Results: Exposures for rectangle and ellipse sources were calculated. The difference between different methods for various sources were 0.88% and 0.61%, respectively. Conclusion: The results estimated by Monte Carlo method are close to those of integration method. It is illustrated that doses of other people estimated by Monte Carlo method are significant
Calcium and phosphorus were mainly responsible for reducing the gastrointestinal absorption of lead in human subjects. The effect of calcium was greater than phosphorus, and their combined effect was more than additive. Increasing weights of calcium and phosphorus progressively reduced lead absorption. The relationship between absorption and increasing weights could be described by two negative exponentials. These effects could be explained if lead competed with calcium and phosphorus for common transport mechanisms in the gut. Milk was also found to reduce lead absorption. Adding milk to the diet of people with low dietary calcium intake could reduce the possibility of increased absorption of ingested lead.
During one year more than 40,000 items of information on radiation exposure of personnel involved in the handling of radiation sources and more than 5,000,000 items on irradiation of other people are collected in the authors' laboratory. Considerable progress in assessment of mean annual gonad dose of genetically sifnificant dose was attained by means of an algorithm for a personal computer. This simple and inexpensive system has led to a higher accuracy in the application of protective measures. (author).
Patients with end stage renal failure (ESRD) require renal replacement therapy in the form of dialysis or renal transplantation. There is an increasing number of people receiving maintenance dialysis as patients with ESRD are increasing faster than the supply of transplantable organs. The mortality rate on dialysis is 4-6 times that of the general population and is substantially reduced by transplantation. For the past 8 years, dialysis research has focused on improving patient outcomes and quality of life on dialysis. This review examines recent advances in haemodialysis and peritoneal dialysis in a historical context and considers future research possibilities. PMID:19329705
There are 110 million people in Sichuan Province, China. Although most of the people in cities of Sichuan use river water, which contains low levels of radon, as potable water, people in countryside and in some communities of big cities still use well water as domestic consumption. This paper reports the radon concentrations in well water investigated in four cities, i.e. Chengdu, Chongqing, Leshan and Leijiang in Sichuan Province. Of the 80 wells investigated, the radon concentrations range from 3.5 to 181.6 KBqm"-"3. Of the four cities, Chongqing has the highest well water radon concentration with the average 49.6 #+-# 54.1 KBqm"-"3 and the greatest variation. The investigation in four cities showed that the radon concentrations in well water are much higher than that in tap-water. In Chongqing where there are complex geological structures, mainly granite stratum, for example, the average radon concentration in well water ...
The objective of the project was to develop an infiltration material based on SiC that should have improved corrosion resistance and should permit higher operating temperatures. From a variety of tested doping agents, zirconium silicide and molybdenum proved to be the most appropriate agents. The respective infiltration materials permit a combination of advantages of the SSiC with those of the SiSiC. Silicide SiC, analogous to the SiSiC, is almost nonshrinking, and above all is more corrosion-resistant than SiSiC in the alkaline regime, due to the replacement of free silicon by silicide phases. The operating temperature of the molybdenum-base variant is 1600 C. (orig./CB) [Deutsch] Ziel des Vorhabens war die Entwicklung eines Infiltrationswerkstoffes auf SiC-Basis mit verbesserter Korrosionsbestaendigkeit und hoeherer Einsatztemperatur. Aus einer Vielzahl von getesteten Dotierungsmoeglichkeiten kristallisierten sich Zirkondisilicid und Molybdaen als geeingete ...
Four trypsin inhibitor homologs, the first known from Dendroaspis angusticeps venom, were characterized using a combination of gel filtration, cation exchange, reverse-phase liquid chromatography, Edman degradation and mass spectrometry. The four toxins comprise two 57 residue and two 59 residue isoforms. The long toxins possess a Lys-Gln N-terminal extension lacked by the short toxins. The only other structural difference is an Arg/His replacement at position 55. The long Arg55 variant is identical to trypsin inhibitor E from the venom of Dendroaspis polylepis. The name epsilon-dendrotoxin is suggested so as to follow the nomenclature of Benishin, C.G., Sorensen, R.G., Brown, W.E., Krueger, B.K., Blaustein, M.P., 1988. Four polypeptide components of green mamba venom selectively block certain potassium channels in rat brain synaptosomes. Mol. Pharmacol. 34, 152-159. Among snake venom protease inhibitors, the epsilon-dendrotoxins are structurally most like the ...
The process of mouse skin tumor formation is subdivided into three operational stages. These stages include initiation, promotion and progression. Ionizing radiation has been found to be a weak initiating agent in the production of malignant squamous cell carcinomas, a complete carcinogen and an agent effective in causing tumor progression. Four skin tumor histologies have been seen with ionizing radiation: benign papillomas, squamous (SCC) and basal (BCC) cell carcinomas and fibrosarcomas. Distinct non-ras transforming genes have been detected in radiation initiated SCCs. A benign papilloma cell line (308) was used as a model system to study ionizing radiation induced progression. A variant 308 cell line (308 10 Gy 5) derived by irradiation of the parental 308 cell has been characterized. The 308 10 Gy 5 cells unlike the parental 308 cells from malignant tumors in athymic nude mice upon subcutaneous injection. The variant 308 10 Gy 5 cells ...
Large-scale decommissioning of Russian nuclear-powered submarines (NPS) and their utilization prospects gave rise to numerous complicated scientific and technical, as well as economic, problems. Problems of handling of radioactive equipment from the reactor compartments (RC) are among the vital ones, arousing a growing concern with the public. Without solution of the problems the processes of NPS utilization can not be considered completed. It involves potential hazard, for the environment both from NPS being paid up (temporal on-float storage) with unloaded spent nuclear fuel (SNF), and RC, cut from submarine hull, containing highly radioactive equipment and materials but no SNF. Diverse variations of the concept of reactor compartment handling of NPS subject to, utilization are possible, but, in principle, there are essentially two variants: (1) RC utilization directly in the course of NPS utilization, envisaging removal of radioactive equipment from the reactor ...
The interaction of accretion disks with the magnetospheres of young stars can produce X-winds and funnel flows. With the assumption of axial symmetry and steady state flow, the problem can be formulated in terms of quantities that are conserved along streamlines, such as the Bernoulli integral (BI), plus a partial differential equation (PDE), called the Grad-Shafranov equation (GSE), that governs the distribution of streamlines in the meridional plane. The GSE plus BI yields a PDE of mixed type, elliptic before critical surfaces where the flow speed equals certain characteristic wave speeds are crossed and hyperbolic afterward. The computational difficulties are exacerbated by the locations of the critical surfaces not being known in advance. To overcome these obstacles, we consider a variational principle by which the GSE can be attacked by extremizing an action integral, with all other conserved quantities of the problem explicitly included as part of the overall ...
This paper provides a brief overview of the young, but rapidly growing field of spintronics. Its primary objective is to explain how as electrons tunnel through simple insulators such as MgO, wavefunctions of certain symmetries are preferentially transmitted. This symmetry filtering property can be converted into a spin-filtering property if the insulator is joined epitaxially to a ferromagnetic electrode with the same two-dimensional symmetry parallel to the interface. A second requirement of the ferromagnetic electrodes is that a wavefunction with the preferred symmetry exists in one of the two spin channels but not in the other. These requirements are satisfied for electrons traveling perpendicular to the interface for Fe-MgO-Fe tunnel barriers. This leads to a large change in the resistance when the magnetic moment of one of the electrodes is rotated relative to those of the other electrode. This large tunneling magnetoresistance effect is being used as the ...
Knowledge and awareness of past and future autobiographical events may be mediated by a common system that supports intentional, goal-directed behavior. The purpose of this study was to assess the correspondence of past and future autobiographical thought. In Experiment 1, 300 undergraduates aged 19 years generated and assigned dates to past and f utu re autobiographical events. Thetemporal distribution of past events replicated a power function for retention as has been described in past research. The intention function of future autobiographical events fit the inverse of this same power function, reflecting a temporality of past and future mental time travel centered around the present moment. In Experiment 2, these findings were extended to young, middle-aged, and older groups. These data provide empirical support for the notion that thinking outside of "now" is mediated by a common system, regardless of whether one is thinking about the past or the future. ...
The western area of the United Stated contains three young silicic calderas, all of which contain attractive targets for scientific drilling. Of the three, the Yellowstone caldera complex is the largest, has the most intense geothermal anomalies, and is the most seismically active. On the basis of scientific objectives alone. it is easily the first choice for investigating active hydrothermal processes. This report briefly reviews what is known about the geology of Yellowstone National Park and highlights unique information that could be acquired by research drilling only in Yellowstone. However, it is not the purpose of this report to recommend specific drill sites or to put forth a specific drilling proposal. 175 refs., 9 figs., 2 tabs.
The evolution of intermediate and high mass stars is reviewed focusing on the interpretation of Pop I Cepheids. First, a summary is given of the classical results of stellar evolution theory for the main evolutionary phases (main sequence and core He-burning) all over the HR diagram, putting into evidence the various points of disagreement with current observational data. Second, models incorporating the effect of convective overshoot, are reviewed, and studies are presented on the rich, young clusters in the Large Magellanic Cloud, in which the models are compared with the observational data. Arguments are given to favor the adoption of models with convective overshoot instead of the classical ones. Third, new results are presented for pulsational models of the Cepheid stars, and the shape of the instability strip in the HR diagram, the number frequency-period distribution, and the mass discrepancy are discussed. 81 refs.
This article examines relevant government policy documents on education and culture and discovers that Nigerian education authorities do not "discriminate" against art and culture in its articulation of educational policies per se, but lack of administrative machinery or political will has resulted in the deprivation of the Nigerian child in the process of creative activity in early childhood development. The article argues that lack of creative ability in our educational products is perhaps a major setback in the nation's quest for industrial and technological development. In this article a new art curriculum for elementary schools is advocated as a means of engaging the young child in order to attain functional educational skills necessary in the world of work.
We estimate the TeV {gamma}-ray fluxes expected from the population of young pulsars in terms of the self-consistent time-dependent hadronic-leptonic model for the high-energy processes inside the pulsar wind nebulae (PWNe). This radiation model is based on the hypothesis of Arons and collaborators who postulate that leptons are accelerated inside the nebulae as a result of resonant scattering on heavy nuclei, which in turn are accelerated in the pulsar wind region or the pulsar inner magnetosphere. Our aim is to find out which PWNe on the northern hemisphere are the best candidates for detection at energies above 60 GeV and 200 GeV by the next generation of low-threshold Cherenkov telescopes.
Background Previous reports in adults have suggested that the effects experienced after cannabis use can be described in terms of positive and negative subtypes that are heritable and are associated with abuse and dependence. This study extends existing research by inclusion of adolescents and young adults in an offspring of twins design which makes it possible to take into account genetic and environmental risks for substance use disorder. Methods Data were collected from 725 twin members of the Vietnam Era Twin Registry, 839 of their 12-32 year old biological offspring and 427 mothers. Offspring who had ever used cannabis (n=464) were asked the degree to which they typically experienced 13 subjective effects shortly after using cannabis. Latent class analysis (LCA) was used to derive sub...
Abstract Young protostars embedded in circumstellar discs accrete from an angular momentum rich mass reservoir. Without some braking mechanism, all stars should be spinning at or near breakup velocity. In this paper, we perform simulations of the self-gravitational collapse of an isothermal cloud using the orion adaptive-mesh refinement code and investigate the role that gravitational torques might play in the spin-down of the dense central object. While magnetic effects likely dominate for low-mass stars, high-mass and Population III stars might be less well magnetized. We find that gravitational torques alone prevent the central object from spinning up to more than half of its breakup velocity, because higher rotation rates lead to bar-like deformations that enable efficient angular mome...
Results that contradict known physics, data manipulated, lack of vigilance by co-authors, failures in the system for scientific publication... Last September a US Committee of Enquiry unveiled one of the most serious frauds in the history of physics. Over a two year period, a young researcher at Bell Laboratories had published a large number of articles with exciting results for solid state physics, but which, alas, were fraudulent! Obviously a fraud of this magnitude is exceptional. However, it did serve to focus attention on the problem of integrity and honesty in research practices. This subject, crucial to the well-being and credibility of scientific research, will be the central theme of the lecture given by Nicholas Steneck, Professor of History at the University of Michigan. A leading expert on this issue, on which he has published extensively, he is a consultant to the Office of Research Integrity in the US, and has been closely involved in public ...
Dusty primordial disks surrounding young low-mass stars are revealing tracers of stellar and planetary formation. The evolution and lifetime of these disks define the boundary conditions of the mechanisms of planet formation. Stellar companions, however, can significantly change this evolution through their tidal interactions. Stellar evolution and planet formation in binaries have to respond to an environment of truncated, quickly disappearing disks--very different compared to an isolated star environment. In order to investigate details of the influence of binarity on circumstellar disk evolution, we obtained adaptive optics supported near-infrared imaging and spectroscopy of the individual components of 22 low-mass binaries in the well-known Orion Nebula Cluster. Brackett gamma emission, which we detect in several systems, is used as a tracer for the presence of an active accretion disk around each binary component. We find a low fraction of accreting binary ...
HCV infection continues to spread at an alarming rate among IDU populations. The available evidence suggests that HCV is acquired relatively quickly following onset of injection. However, there are few prospective studies of HCV acquisition, particularly among IDU populations in resource-poor settings. A sample of young male heroin injectors with recent onset of injection (<4?years) was recruited in Hanoi, Vietnam for a prospective assessment of the early course of injection (n?=?179). Both behavioral and biological assessments (including detailed retrospective assessment of injection initiation) were conducted at baseline and repeated at 6-month intervals for a period of 16?months. Variables associated with HCV infection (p value?p value?=?0.0005). In multivariate logistic regression anal...
Polysomaty analysis of the succulent portulaca (Portulaca grandiflora Hook.) plant was carried out using flow cytometry. For both diploid and tetraploid plants, mature leaf tissue was found to have a higher level of polysomaty than young leaf tissue. Mesophyll (MP), bundle sheath (BSP) and water storage protoplasts (WSP) were isolated from leaf tissues of diploid portulaca plants. WSP had a higher degree of endopolyploidization than MP and BSP. The ploidy distribution was also variable in different floral organs. Tetraploid plants artificially induced by colchicine treatment showed a decline in the degree of polysomaty compared to diploid plants. Tetraploid plants had more spherical leaves, a larger number of petals and lower pollen fertility than diploid plants. PMID:10936528
Concerns for potential vulnerability to manganese (Mn) neurotoxicity during fetal and neonatal development have been raised due to increased needs for Mn for normal growth, different sources of exposure to Mn, and pharmacokinetic differences between the young and adults. A physiologically based pharmacokinetic (PBPK) model for Mn during human gestation and lactation was developed to predict Mn in fetal and neonatal brain using a parallelogram approach based upon extrapolation across life stages in rats and cross-species extrapolation to humans. Based on the rodent modeling, key physiological processes controlling Mn kinetics during gestation and lactation were incorporated, including alterations in Mn uptake, excretion, tissue-specific distributions, and placental and lactational transfer ...
The effects of exposure to sublethal levels of microwaves were studied. Young albino rats of both sexes were exposed for 60 days to 7.5-GHz microwaves (1.0-KHz square wave modulation, average power 0.6 mW/cm2) for 3 h daily. During and after microwave exposure several physiological parameters were measured in both control and exposed animals. It was found that the animals exposed to microwaves tended to eat and drink less and thus showed a smaller gain in body weight. Some of the hematological parameters and organ weights were also significantly different. It is proposed that a nonspecific stress response due to microwave exposure and mediated through the central nervous system is responsible for the observed physiological changes.
Purpose We retrospectively analyzed the results of percutaneous nephrolithotomy operations for treatment of staghorn kidney stone disease in elderly patients and compared surgical parameters and outcomes with a control group of young adult patients. Patients and method Between 2002 and 2010, 300 consecutive patients underwent percutaneous nephrolithotomy operation for treatment of staghorn kidney stone disease. Forty-five of the patients were older than 65?years and considered to be in elderly group. Thirty-seven of the patients were between the ages 18 and 36?years and considered to be the control group. Surgical parameters and outcomes were compared between groups. Results There were no significant differences between groups for stone area, operation time, difference in hemoglobin levels...
Although infrared-stimulated luminescence (IRSL) signals in feldspars can be bleached rapidly by sunlight, there could still be a small amount of IRSL signal remaining in sediment grains if they have experienced only relatively short sunlight exposure before deposition. This remaining signal results in a ''remnant dose'' stored in the grain and is important for young samples but negligible for old samples. Several methods have been introduced to detect insufficient bleaching, and some of them can provide information on the extent of the bleaching. Others can only distinguish between samples bleached for a very long time and for a short time. Empirical methods are introduced to evaluate the possible values of equivalent dose accumulated since the grains were deposited. These methods involve the analysis of the equivalent doses and the natural IRSL signals obtained using single-disc dose determination methods. (author).
This article reviews the little examined early work of the Greek Marxist and state theorist, Nicos Poulantzas (1936-1979). In his first book, Nature du choses et droit of 1965, the young scholar developed a sociology of law culled from the insights of philosophical ontology. The article sets out the central claims of that book and reflects on its place in Poulantzass intellectual development. Drawing on Heidegger, Sartre and Marx, Poulantzas proposed a species of Natural Law theory that unified `facts' and `values' by grounding legal concepts in a theory of social praxis centred on material labour. Legal categories were thus irreducible to ahistorical essences but were, rather, expressions of mankinds struggle to realize its intrinsic freedom. As we shall see, although flawed and in key re...
An evolutionary model of dynamical processes in protostellar disks is described and illustrated with graphs of typical results. The effective transport mechanisms are discussed, including thermal convection, nonaxisymmetric gravitational instabilities in the outer regions of disks, and wave propagation. Consideration is then given to the stages of dynamical evolution, FU Ori outburst phenomena, unsteady accretion-disk flows, and nonlinear feedback as a mechanism to modulate mass transfer. The simulations show that mass redistribution is determined by angular-momentum transfer, which in turn is regulated by the effective viscosity generated by convectively driven turbulence. Significant mass transfer occurs as a result of mixing of infalling material with disk gas and is affected by the tidal torque associated with the growth of nonaxisymmetric disturbances in the outer disk. The time scale for disk evolution is found to be about 1 Myr. 72 refs.
This is the final report of a three-year, Laboratory Directed Research and Development (LDRD) project at the Los Alamos National Laboratory (LANL). The authors investigated the evolution and radiation characteristics of individual neutron stars and stellar systems. The work concentrated on phenomena where new techniques and observations are dramatically enlarging the understanding of stellar phenomena. Part of this project was a study of x-ray and gamma-ray emission from neutron stars and other compact objects. This effort included calculating the thermal x-ray emission from young neutron stars, deriving the radio and gamma-ray emission from active pulsars and modeling intense gamma-ray bursts in distant galaxies. They also measured periodic optical and infrared fluctuations from rotating neutron stars and search for high-energy TeV gamma rays from discrete celestial sources.
A Y-Mg-Si-Al-O-N glass was submitted to swift heavy-ion bombardment at GANIL (Caen, France) and the influence of irradiation on the mechanical properties was studied. The mechanical properties of the glass were characterized both before and after irradiation. Changes in hardness, elastic modulus and fracture toughness of the near-surface irradiated layer were determined using indentation techniques. SRIM calculations allowed to estimate the ions penetration range and the energy deposition relative to electronic and nuclear interactions, which can be correlated to the experimental damaged depth. Meyer's hardness and Young's modulus decrease by about 30 %, while fracture toughness is increased by more than 40 %. (authors)
A 2-year-old, female spayed, domestic shorthair cat presented to the University of Missouri-Veterinary Medical Teaching Hospital (UMC-VMTH) with an approximately 11-month history of fluid-draining pockets along her ventral thorax and axillae. The skin in these regions was erythematous, and multiple areas drained a serous to serosanguinous fluid. Fluid-filled, nodules formed along the ventrum, but these nodules disappeared as fluid drained spontaneously. Histologic assessment of skin biopsies revealed areas of vascular proliferation extending along the deep margin of the section and rare instances of invasion into the superficial dermis. These vascular channels were devoid of cells, lined by variably pleomorphic endothelial cells which had a low mitotic index. Based on the mild to moderate ...
Observations are reported of the lithium feature (6708 A) in some bright southern stars, most of which are F, G, or K dwarfs. Three of these stars have been suggested as belonging to the Ursa Major Group. Two of these three have the large Li abundance and strong Ca II H and K emission expected of such young stars. The third potential Ursa Major Group member has little Li, but is also not a true kinematic member. No stars were found with abnormal (Li-6)/(Li-7) ratios, in accord with other recent analyses. Thus it appears that all stars have (Li-6)/(Li-7) near the solar/terrestrial value of 0.08. 31 references.
A rare case of primary splenic cyst is shown in a young woman who had a left subcostal abdominal pain. Abdominal echography and CT scan revealed a cyst of the anterior aspect of the spleen. A sorologic test for hidatic disease was negative. On the basis of a presumed diagnostic of nonparasitic cyst, the patient was referred to a laparoscopic decapsulation with excision of the cysts wall not covered by splenic tissue. The patient was discharged 24 hours later. Histological report revealed epidermoid cyst. The laparoscopic approach has being recently considered an effective and less invasive alternative in the treatment of splenic diseases. We demonstrated that it should be considered for the treatment of splenic cysts present in a superficial location, with the advantage of organ preservation. (author)
An international conference on forestry research presented papers on topics including forest mensuration, growth and yield; growth/yield relationships; design, performance, and evaluation of experiments; forest resource inventory and monitoring techniques; forest management, planning, and managerial economics; forestry and rural development in developing countries; forestry in sustainable economic development; conceptual advances in multiple-use forestry evaluations; economic evaluation of forest damages; supply and demand of roundwood and forest industry products; forestry and rural development in industrialized countries; analysis and evaluation of forest policies; forest institutions and organizations; biological and economic considerations when harvesting young thinning stands; applied sector modelling; and structural changes of the forest sector in a global perspective. Separate abstracts have been prepared for 3 papers from this conference.
Fly ash from Lagisza power station with addition of kaolin and calculated amount of carbon was reacted in flowing nitrogen at 1520"oC in order to obtain #beta#-sialon. The resulted powder was sintered with and without Y_2O_3 addition. Examinations show that it is possible to sinter that material without any sintering additives, however additive of Y_2O_3 decreases sintering temperature of about 100"oC. Sintering temperature influences the final mechanical properties like: flexural strength, microhardness, Young elastic modulus (E) and fracture toughness (K_I_c). (author)
From the first principles total energy calculations based on full-potential linear augmented plane wave method (FPLAPW), the elastic properties of XPt_3 (X=V, Cr, Mn, Fe, Co, Ni) are reported here. Theoretical values of Young's modulus, shear modulus, Poisson's ratio and Debye temperature are estimated from the computed elastic constants. From the analysis of the ratio of shear to bulk modulus, it is found that these intermetallic compounds are ductile in nature except CrPt_3, which is brittle. The calculated results are compared with other reported values.
The Sultanate of Oman has a relatively young national health care system that could demonstrate its high performance at an international level. Emergency medicine as a specialty has developed rapidly in the country over the last decade. This has involved the parallel development of local emergency residency training, prehospital emergency care, and emergency nursing programs. This article reviews the progress of emergency care practice in this country from a general primary care system toward becoming an established specialty in hospital, prehospital, and private emergency care settings. It also describes aspects of undergraduate, postgraduate, and continuous emergency medicine education in the country. Further, a glimpse into academic emergency medicine and emergency nursing is provided. ...
Dense samples of #beta#-sialons (with z from 1 to 4) were pressuressly sintered for different time (15-240 minutes) and at relatively low temperature of 1600 C using single-phase #beta#-sialon powders synthesized by combustion nitridation. The samples were characterized using ultrasonic method for determination of elastic properties (E,G,#mu#). Also, hardness by Knoop and fracture toughness by Vickers indentation microfracture method was estimated. With increasing z number Young's modulus decreases from 293 to 179 GPa. Simultaneously Poisson ratio increases by about 30%. The highest values of hardness and fracture toughness were obtained for sialon with z equal to 1. (orig.).
Six different groups of non-smoking young male subjects were studied separately for 18 consecutive days each in a closed controlled-environmental human exposure chamber. Each group was subjected to a 5-day control period in fresh air followed successively by an 8-day period of continuous exposure to 50 ppm, 15 ppm or 0 ppm (control) by volume of carbon monoxide (CO) in air, and a 5-day recovery period in fresh air. The subjects performed a 1-h auditory vigilance task every day at the same time of day in a fixed qualitative, quantitative, and temporal relationship with food intake, consumption of stimulating beverages, physical activity, and sleep. It was concluded that such CO exposure, involving the continuous carriage of carboxyhaemoglobin loads up to 7%, was without significant effect on auditory vigilance.
Young children are at increased risk for valproic acid (VPA) hepatotoxicity. Urinary organic acid profiles, as a surrogate of mitochondrial function, were obtained in children 1.9 to 17.3 years of age (n = 52) who were undergoing treatment with VPA for seizure disorders. Age-matched patients receiving treatment with carbamazepine (CBZ; n = 50) and healthy children not undergoing treatment (n = 22) served as controls. Age-related changes in organic acid profiles were observed in all three groups. Although the untreated and CBZ control groups were indistinguishable from each other with respect to the principal-component analysis (PCA) score plots of the subjects, a distinct boundary was apparent between the VPA and each of the control groups. Interindividual variability was observed in the V...
Young rats were given a single irradiation dose (0.5, 2, 5 or 8 Gy) to the left knee-joint. The right unexposed knee-joint served as control. The animals were decapitated 1.5, 3, 7, 14 or 30 days after the irradiation. Longitudinal bone growth in the tibial epiphysis was established using tetracycline as an intravital marker. During the first 1.5 days after irradiation with 5 and 8 Gy, the growth was slightly inhibited (6-7%). Maximum growth retardation (20%) was found 7 to 14 days after irradiation with 5 and 8 Gy. No consistent effect occurred after 0.5 and 2 Gy. Between 14 to 30 days following irradiation growth was normalized.
This three-part article describes the early years of one of the mother-baby-children groups of the Project for Mothers, Infants, and Young Children of September 11, 2001. The goal of the group was to help prevent the effects of trauma and loss from disrupting the relationships among the mothers, their infants, and growing children. View I by Anni Bergman describes the mothers' states of minds as the group began, when they felt that their worlds had collapsed under them. View II by Sally Moskowitz focuses on the clinical experience of working in the group, transference and countertransference themes, helping the mothers and children with their mourning process, and helping the mothers' relationships to each other, their babies, older children, family, and friends. The evolution of a casual,...
The last decade has produced an explosion in neuroscience research examining young children's early processing of language that has implications for education. Noninvasive, safe functional brain measurements have now been proven feasible for use with children starting at birth. In the arena of language, the neural signatures of learning can be documented at a remarkably early point in development, and these early measures predict performance in children's language and pre-reading abilities in the second, third, and fifth year of life, a finding with theoretical and educational import. There is evidence that children's early mastery of language requires learning in a social context, and this finding also has important implications for education. Evidence relating socioeconomic status (SES) ...
A new method for determining the year of birth, the year of death, and hence, the age at death, of post-bomb and recently deceased elephants has been developed. The technique is based on Accelerator Mass Spectrometry radiocarbon analyses of small-sized samples extracted from along the length of a ge-line of an elephant tusk. The measured radiocarbon concentrations in the samples from a tusk can be compared to the {sup 14}C atmospheric bomb-pulse curve to derive the growth years of the initial and final samples from the tusk. Initial data from the application of this method to two tusks will be presented. Potentially, the method may play a significant role in wildlife management practices of African national parks. Additionally, the method may contribute to the underpinnings of efforts to define new international trade regulations, which could, in effect, decrease poaching and the killing of very young animals.
The thermal properties (thermal conductivity, thermal diffusivity, thermoelectric power, thermal dilatation, etc.) and the mechanical properties (Young's modulus, strength, hardness, fracture toughness, etc.) have been measured at low temperatures (4-300K) and under a high magnetic field (0-10T) for about 50 REBaCuO bulks (RE=Y, Gd, Nd, Sm, Dy, etc.). We have constructed the database of these properties and opened it on the Web site (thermal properties: http://ikebehp.mat.iwate-u.ac.jp/database.html and mechanical properties: http://paris.mech.iwate-u.ac.jp/sc-bulk/database.html). The influence of the species of RE ions, the content, size and dispersion of the RE211 (or Nd422) phase and Ag particles and the defects distribution on these properties is characterized.
The lower condition factors for two catfish species in water heated by effluents from APCo's Glen Lyn, Virginia plant as compared to control areas probably is not due to lack of food as evidenced by macroinvertebrate sampling and the fact that only 4.3 percent of the catfish stomachs were empty. Results suggested that young-of-the-year channel catfish were nonselectively eating food organisms present at both control and heated stations. The difference between stomach contents of flatheat catfish from the heated site and fauna available at that site indicated that fish were either moving out of the heated area to feed or were selectively feeding on organisms (particularly mayflies) which were in the substrate or drifted into the heated area. Stomach contents of the two species and distribution and abundance of the macroinvertebrate benthos community are detailed.
Recent legislative changes in both Europe and the USA have increased the responsibility of drug developers to purposefully study the agents they market in children so that specific dosing recommendations can be made to assist clinicians in their use. Typically, clinicians use empirical- or experiential-based rationales for selecting the dose to use in children, generally in a manner that attempts to achieve the same dose-exposure or pharmacokinetic profile in children as in adults. However, whether this approach achieves the necessary dose exposure or exposure effect needed may not be systematically explored during off-label use. This creates the opportunity for under- or over-exposure in children, particularly in very young children (i.e., less than 2 years old) where a combination of fac...
Spatial skills are a central component of intellect and show marked individual differences. There is evidence that variations in the spatial language young children hear, which directs their attention to important aspects of the spatial environment, may be one of the mechanisms that contributes to these differences. To investigate how play affects variations in language, parents and children were assigned to 1 of 3 conditions: free play with blocks, guided play, or play with preassembled structures (Study 1). Parents in the guided play condition produced significantly higher proportions of spatial talk than parents in the other two conditions, and children in the guided play condition produced significantly more spatial talk than those in the free play condition. Study 2 established baseli...
The problem of model selection arises in a number of contexts, such as subset selection in linear regression, estimation of structures in graphical models, and signal denoising. This paper generalizes the notion of "incoherence" in the existing literature on model selection and introduces two fundamental measures of coherence---termed as the worst-case coherence and the average coherence---among the columns of a design matrix. It utilizes these two measures of coherence to provide an in-depth analysis of two variants of a simple one-step thresholding (OST) algorithm for model selection and proves that OST is feasible for model selection as long as the design matrix obeys an easily verifiable property. One of the key insights offered by the ensuing analysis in this regard is that if the design matrix has reasonably small worst-case and average coherence then OST performs near-optimally when either (i) the energy of any nonzero entry of the signal is close to the ...
Directed evolution of proteins depends on the production of molecular diversity by random mutagenesis. While a number of methods have been developed for introducing this diversity, the best ways to sample it are not always clear. Here we used simple statistics to analyse completeness and diversity in randomized libraries generated by oligonucleotide-directed mutagenesis, error-prone polymerase chain reaction (epPCR) and in vitro recombination of highly homologous sequences. For oligonucleotide-directed mutagenesis, we derive equations to estimate how complete a given library is expected to be and also to predict the size of library required to give a fixed probability of being 100% complete. We describe the statistical bases for computer programs which estimate the number of distinct variants represented in epPCR and shuffled libraries, dubbed PEDEL and DRIVeR, respectively. These programs allow the user to calculate (rather than guess) the diversity represented in ...
The authors investigated the development of tribochemical reaction layers and surface-level structural changes in a fuel-lubricated roller bearing steel 100Cr6 in the limiting friction range, using two different variants of surface treatment and heat treatment. Tribological experiments were carried out in a laboratory test stand with reversing sliding wear under varying loads and with a varying number of friction cycles. [German] Ziel der vorliegenden Arbeit war es, die Entstehung von tribochemischen Reaktionsschichten und oberflaechennahen Gefuegeaenderungen am Waelzlagerstahl 100Cr6 bei Kraftstoffschmierung im Grenzreibungsbereich fuer je zwei Oberflaechenbearbeitungen und Waermebehandlungen zu untersuchen. Dazu wurden tribologische Kurzversuche in einem Laborpruefstand mit reversierender Gleitbeanspruchung unter Variation der Last und der Anzahl der Reibzyklen durchgefuehrt. (orig.)
subsequent to its in-reactor dwell time, spent fuel still contains large amounts of materials that are recoverable, for value-added energy purposes (uranium, plutonium), together with fission products, and minor actinides, making up the residues from nuclear reactions. The treatment and recycling of spent nuclear fuel, as implemented in France, entail that such materials be chemically partitioned. The development of the process involved, and its deployment on an industrial scale stand as a high achievement of French science, and technology. Treatment and recycling allow both a satisfactory management of nuclear waste to be implemented, and substantial savings, in terms of fissile material. Bolstered of late as it has been, due to spectacularly skyrocketing uranium prices, this strategy is bound to become indispensable, with the advent of the next generation of fast reactors. This Monograph surveys the chemical process used for spent fuel treatment, and its ...
Describes progress made with the new economic system in the USSR coal industry since full self-financing was introduced on 1 January 1989, pointing out that mining is now being carried out at greater depths than before (515 m in 1988, 457 m in 1981 on the average) and that an increasing proportion of coal is being produced by mines liable to coal and gas bursts (62.3% in 1988, 59.6% in 1981). More difficult conditions means that mining costs are increasing. Explains system of agreements between teams of workers and mine management regarding output and extraction costs. Reveals that on 1 January 1990 a new list of coal prices will include 90% price rises on average, as a result of need for mines to finance themselves. There are to be 2 variants of this price list: one containing standard nationwide prices, the other based on mining areas, taking into account different geological and other conditions. Concludes by emphasizing the need to improve productivity, by ...
In an adiabatic low-pressure calorimeter, the temperature dependence of the standard molar heat capacity of paramagnetic dicarbonyl rhodium complex with o-semiquinone (CO){sub 2}Rh(SQ) has been determined in the range from T=(6 to 355)K mainly with an accuracy of about 0.3%. Over the ranges from T=(205 to 234) K, T=(266 to 315)K and T=(316 to 345)K physical transformations have been revealed and their enthalpies and entropies have been estimated. The experimental data were used to calculate the thermodynamic functions C{sub p,m}{sup o}/R,{delta}{sub 0}{sup T}H{sub m}{sup o}/(R.K),{delta}{sub 0}{sup T}S{sub m}{sup o}/R and {phi}{sub m}{sup o}={delta}{sub 0}{sup T}S{sub m}{sup o}-{delta}{sub 0}{sup T}H{sub m}{sup o}/T (where R is the universal gas constant) between T=(0 and 355)K. The fractal dimension D in the heat capacity function of the fractal variant of Debye heat capacity theory has been evaluated.
The present study has examined for #alpha#/#beta#-Ti alloys the relationship between the morphology and crystallography of Widmanstaetten plates of #alpha#-Ti in colonies within a prior grain of #beta#-Ti. Thus, optical metallography, scanning electron microscopy and transmission electron microscopy have been used to characterize the morphological features of the microstructure, whereas orientation-imaging microscopy (OM) and transmission electron microscopy (TEM) have been employed to reveal crystallographic information. It has been discovered that within a prior #beta#-Ti grain, although the growth direction of the Widmanstaetten plates in given colonies may differ by large angles from #alpha#-plates in other colonies, they may exhibit very close crystallographic relationships. For example, inclined #alpha#-plates may share common basal planes and be related by a rotation of #approx#10.5 deg. about the c-axis of the crystals. This phenomenon has been interpreted on the basis of ...
The paper presents the progress of the Radioactive Waste Management Plan which accompanies the Decommissioning Plan for research reactor WWR-S located in Magurele, Ilfov, near Bucharest, Romania. The new variant of the Decommissioning Plan was elaborated taking into account the IAEA recommendation concerning radioactive waste management. A new feasibility study for WWR-S decommissioning was also developed. The preferred safe management strategy for radioactive wastes produced by reactor decommissioning is outlined. The strategy must account for reactor decommissioning, as well as rehabilitation of the existing Radioactive Waste Treatment Plant and the upgrade of the Radioactive Waste Disposal Facility at Baita-Bihor. Furthermore, the final rehabilitation of the laboratories and reusing of cleaned reactor building is envisaged. An inventory of each type of radioactive waste is presented. The proposed waste management strategy is selected in accordance with the IAEA ...
The iron hormone hepcidin is inhibited by matriptase-2, a liver serine-protease encoded by TMPRSS6 gene. Cleaving the BMP-coreceptor hemojuvelin, matriptase-2 impairs the BMP/SMAD signaling pathway, downregulates hepcidin and facilitates iron absorption. TMPRSS6 inactivation causes iron-deficiency-anemia refractory to iron administration both in humans and mice. Genome wide association studies have shown that the SNP rs855791, which causes the matriptase-2 V736A amino acid substitution, is associated with variations of serum iron, transferrin saturation, hemoglobin and erythrocyte traits. Here we show that in vitro matriptase-2 736(A) inhibits hepcidin more efficiently than 736(V). Moreover, in a genotyped population, after exclusion of samples with iron deficiency and inflammation, hepcidin, hepcidin/transferrin saturation and hepcidin/ferritin ratios were significantly lower and iron parameters were consistently higher in homozygotes 736(A) than in 736(V). Our results indicate that ...
The syntheses of N-alkylated deoxynojirimycin and 1,5-dideoxy-1,5-iminoxylitol derivatives having either a D- or an L-erythritol-3-sulfate functionalized N-substituent are reported. The alkylating agent used was a cyclic sulfate derivative, whereby selective attack of the nitrogen atom at the least hindered primary center afforded the desired ammonium salt. In aqueous solution, these salts were configurationally labile at the ammonium center. Sulfonium and/or selenonium analogues of the ammonium salts were prepared by analogous reactions. The chalcogen salts were obtained as mixtures of diastereomers, separable in some cases, differing only in the stereochemistry at the configurationally stable sulfur or selenium atoms. Proof of configuration and conformation of each compound was obtained by detailed NMR experiments. The compounds are six-membered ring analogues of salacinol, a known sulfonium-salt glucosidase inhibitor. Evaluation of the target compounds for enzyme inhibition of the ...
An original device and a method of its application for restoring of the function of relatively incompetent valves (both patented) are elaborated. Application of the new device allows to lower the difficulty of surgical treatment, to decrease the duration of operation and post-operative period. The long-term results of six-year long experience of its application are presented. The patients examination after 2,5-3,0-year post-operation period shows perfect vein valve correction. A device for stone extraction from tubular organs (patented) fabricated with titanium nickelide superelastic alloy is presented. The new suggested design is free of the drawback inherent in the previous one. The working element of the device is formed as a truncated cone or a truncated cone coaxial with the cylinder (the previous design was formed as a full cone) that prevents overstraining and residual strain accumulation during the manipulation process. Since the first publication the design of spiral stent and ...
Material testing of SPF-sheet is usually done with coupon hot tensile testing. The optimum range of strain rates is determined with stepped strain tests. To overcome the problem of very few available testing facilities and time consuming and costly procedure, cone cup testing has been developed since long. This test can be generated directly in the workshop, no machining of samples is necessary and it is very much related to the real SPF-process. The analysis of suitable temperature and strain rate is done by simple measurement of resulting cone height. This paper describes a unique and novel variant of the above mentioned baseline design. It provides on-line data of the actual status of the cone cup forming resulting from the applied, constant pressure. Strain rate variations as a result from texture or from the alloy-related behaviour is detectable. Thinning and ''hardening'' behaviour of different alloys up to maximum failure ...
The nature of the 5f electronic structure of plutonium (Pu) remains unclear. [1] Despite many recent attempts to resolve the issue, a plethora of important unanswered questions remain. While many theoretical approaches to the problem have been promulgated, the real source of the difficulty is the absence of sufficient experimental benchmarking. This paucity of impact on the part of experimental results is driven in part by the difficulties of working with Pu: it is highly radioactive, biologically toxic, chemically reactive and restricted in its distribution and permitted access to user facilities. The results of these liabilities include the following: (1) it is very difficult, if not impossible, to get large single crystals of single phase samples and; (2) many state of the art experiments can not be done because general user facilities are not available for use with Pu samples. Additionally, there is the apparently bizarre nature of Pu, which seems to defeat the efforts to analyze ...
Until now, monitoring of power transformers focussed mainly large generator and network transformers. Siemens goes a step ahead and provides a system especially developed and designed for small and medium power transformers, e.g. for the 100 kV level. This low cost version could be achieved by restriction to really necessary measuring quantities. This allows to realize also for small and medium power transformers an online monitoring including an estimation of aging and as an option an early warning to avoid unexpected failures. (orig.) [German] Die Ueberwachung (Monitoring) von Leistungstransformatoren war bisher vor allem fuer Maschinentransformatoren und grosse Netzkuppeltransformatoren in der Diskussion. Siemens geht einen Schritt weiter und stellt nun auch ein System bereit, das speziell fuer kleine und mittlere Leistungstransformatoren, z.B. der 110-kV-Spannungsebene, konzipiert ist. Diese kostenguenstige Variante wurde durch Beschraenkung auf die aus ...
We show that a general variant of the Wick theorems can be used to reduce the time ordered products in the Gell-Mann and Low formula for a certain class on non local quantum field theories, including the case where the interaction Lagrangian is defined in terms of twisted products. The only necessary modification is the replacement of the Stueckelberg-Feynman propagator by the general propagator (the 'contractor' of Denk and Schweda) D(y-y';#tau#-#tau#')=(1)/i(#DELTA#_+(y-y')#theta#(#tau#-#tau#')+#DELTA#+(y'-y)#theta#(#tau#'-#tau#)), where the violations of locality and causality are represented by the dependence of #tau#,#tau#' on other points, besides those involved in the contraction. This leads naturally to a diagrammatic expansion of the Gell-Mann and Low formula, in terms of the same diagrams as in the local case, the only necessary modification concerning the Feynman rules. The ordinary local theory is easily recovered as a special case, and there is a ...
The effects of neutron irradiation on the superconducting and normal state properties of alloys and compounds are presented. Particular emphasis is placed on the A-15 compounds where the effects of neutron irradiation on Tsub(c), Hsub(c_2), long range order parameter and lattice parameter are described. Large depressions (up to 80%) in Tsub(c) are observed for all the A-15 compounds studied with the exception of Mo_3Os where much smaller decreases in Tsub(c) are seen. Along with the decrease in Tsub(c) and increase in lattice parameter, the degree of long range order, as measured by X-ray and neutron diffraction, decreases. Also presented are the results of isothermal and isochronal anneals up to 900"0C. The unirradiated value of Tsub(c) can be restored by annealing, and for those systems where measurements have been made, recovery of the lattice parameter and order parameter also takes place. The effects observed in irradiated material, together with those observed in unirradiated but ...
High resolution Monte-Carlo simulations show that the neutron spectrum, fuel burnup and fuel temperature feedback effect of a PWR core loaded with Thoria-based fuel (Th/Pu-O_2) do not significantly differ from the MOX fuelled one due to the similar neutronic characteristics of both fertile materials (Th-232, U-238). The core physics of this fuel variant is characterized by an enhanced moderator/void temperature coefficient (by factor 2.4) and high incineration rate for Pu (approx. 60 %). A PWR core loaded with the Molybdenum-based inert matrix fuel (IMF) - in contrast to MOX-, shows a harder spectrum, resulting in small temperature coefficients of reactivity and particularly in a higher fuel depletion rate as well as an enhanced TRU reduction performance. The incineration of Pu amounts to 46 % resulting, in turn, in generation of minor actinides of about 10 % of the total Pu consumption. The higher excess reactivity resulting from the initial Pu contents is ...
Purpose: To determine the value of MRI in the preoperative evaluation of chronic paranasal sinusitis and to compare the results with CT and intraoperative findings. Method/Materials: 42 patients with clinical signs of chronic paranasal sinusitis underwent MRI after CT evaluation on one day, with subsequent functional endoscopic sinus surgery on the next day. Coronary CT was obtained with 5-mm slices and table-feed in the prone position, while MRI was performed in the supine position with coronary T_2-TSE+pd and coronary and transverse HASTE, each with 5-mm slice thickness. Aquisition time in MRI was less than 8 minutes. Two radiologists reviewed the CT and MRI scans for signs of sinusitis and detection of anatomical landmarks. The results were correlated with the intraoperative findings. Results: MRI offered no artifacts of dental work and showed more often high quality pictures than CT. CT and MRI demonstrated a good correlation in the detection of mucosal pathologies ...
Endoreduplication represents a cell cycle variant during which multiple rounds of DNA replication occur without subsequent chromosome separation and cytokinesis, resulting into a cellular increase of the DNA content. Although the DNA ploidy level of cells is controlled by external stimuli such as light, currently limited knowledge is available on how environmental signals regulate the endoreduplication cycle at the molecular level. Previously, we have demonstrated that the conversion from the mitotic cell cycle into an endoreduplication cycle is mediated by the atypical E2F transcription factor DEL1 that operates as a repressor of endocycle onset. Here, we identified DEL1 as a transcriptional target of the classical E2Fb and E2Fc transcription factors that antagonistically control DEL1 transcript levels through competition for a single E2F cis-acting binding site. Correspondingly with the reported opposite effect of light on the E2Fb and E2Fc protein levels, the ...
An investigation was carried out to determine the significance of a large input of cogeneration units for the electric power generation, next to the input of coal and uranium. Thereto a production plant has been set up to generate heat and electric power. The plant serves as a basis for a number of comparative calculations: basic calculations to investigate the influence of some strategies on the cogeneration input, and sensitivity calculations to determine the influence of a few changes in the starting points. Some variants have been deduced from this plant, which is based on prognosis for the year 2000. By means of the computer calculation program OPINIE (Optimale Inzet en Instelling van Eenheden: Optimal Input and Installation of Units) the minimal variable costs were calculated for different situations. Finally for each considered situation the total annual costs have been calculated. 53 figs., 13 refs., 30 tabs., 3 apps.
Aims: The present study explored the integrative effect of genes encoding methadone pharmacokinetic and pharmacodynamic pathways on methadone maintenance doses in Han Chinese Patients. Materials & methods: Genomic DNA was extracted from 321 opioid-dependent patients and 202 healthy controls, and realtime-PCR and PCR-RFLP were conducted to determine the genotypes. Results: Pair-wise comparisons revealed that carriers of the variants ABCB1 3435C>T or CYP2B6 516G>T alleles were more likely to require a higher methadone dose than noncarriers (both p G or 939C>T allele had a two-fold chance of requiring a lower methadone dose than noncarriers (p = 0.001). Proportional odds regression with adjustment of cofactors demonstrated that ...
Chemical analyses were done on the abnormal hemoglobins of the five (101 x SEC)F_1 offspring of X- irradiated adult SEC mice to determine which hemoglobin genes were expressed in each hemoglobin variant. Three offspring of irradiated SEC males did not express either of the two kinds of #alpha#-chains normally found in all SEC mice. The deficient #alpha#-chain synthesis caused these mice to exhibit an #alpha#-thalassemia similar to human #alpha#-thalassemia. Scanning electron microscopy was used to show that many erythrocytes of mice with #alpha#-thalassemia have bizarre shapes; e.g. many erythrocytes appeared flattened or had thorny projections (acanthocytes). One mutant with a tandem duplication of a segment of chromosome 7 (site of locus determining #beta#-chain structure) produced twice as much SEC as 101 #beta#-chain polypeptides. One mutant that probably arose by non-disjunction of chromosome 7's in its unirradiated 101 mother and loss of chromosome 7 from the ...
The Cahn-Hilliard-Navier-Stokes system is based on a well-known diffuse interface model and describes the evolution of an incompressible isothermal mixture of binary fluids. A nonlocal variant consists of the Navier-Stokes equations suitably coupled with a nonlocal Cahn-Hilliard equation. The authors, jointly with P. Colli, have already proven the existence of a global weak solution to a nonlocal Cahn-Hilliard-Navier-Stokes system subject to no-slip and no-flux boundary conditions. Uniqueness is still an open issue even in dimension two. However, in this case, the energy identity holds. This property is exploited here to define, following J.M. Ball's approach, a generalized semiflow which has a global attractor. Through a similar argument, we can also show the existence of a (connected) global attractor for the convective nonlocal Cahn-Hilliard equation with a given velocity field, even in dimension three. Finally, we demonstrate that any weak solution fulfilling ...
To analyze and review the most common focal lesions of the external auditory canal (EAC), describing the computed tomography (CT) findings. The CT images of EAC were reviewed in a series of 167 patients. Abnormal findings were recorded in 13 cases. The CT images were correlated with otoscopic and/or intraoperative findings. There were four cases of osteoma (one located outside the EAC); all of which were treated surgically, as was the one case of exostosis. Six patients presented debris in EAC, coinciding with clinical evidence of external otitis. There were two cholesteatomas derived from EAC, one of them secondary to survery to treat osteoma. On patient was diagnosed as having a basal cell carcinoma of the ear, extending to EAC, but refused to undergo surgery. Five patients presented small triangular laminae of dense bone arising from the upper wall of the EAC which were defined as abnormal variants of the fusion of the temporal squamous epithelium to the ...
Certain 6000-series extrusions may develop susceptibility to intergranular corrosion (IGC) by improper heat treatment, especially if copper is present as an alloying element. Although occurrence of IGC in such cases is documented, the underlying mechanisms are not adequately explained. We present corrosion data for two model alloys, having different Cu content and Mg:Si ratio, showing that the susceptibility to IGC depended primarily on the Cu content and secondly on thermal processing. Low Cu samples (0.0005 wt.% Cu) were essentially resistant to IGC. High Cu samples (0.12 wt.% Cu), which were air cooled after extrusion, exhibited significant IGC. However, IGC susceptibility was reduced significantly as a result of artificial aging to peak strength. Water quenched high Cu samples were essentially resistant to IGC. However, slight IGC susceptibility was introduced after aging. Electron optical characterisation revealed Al_4Mg_8Si_7Cu_2 (Q-phase) grain boundary precipitates on all the ...
Modern text retrieval systems often provide a similarity search utility, that allows the user to find efficiently a fixed number k of documents in the data set that are most similar to a given query (here a query is either a simple sequence of keywords or the identifier of a full document found in previous searches that is considered of interest). We consider the case of a textual database made of semi-structured documents. Each field, in turns, is modelled with a specific vector space. The problem is more complex when we also allow each such vector space to have an associated user-defined dynamic weight that influences its contribution to the overall dynamic aggregated and weighted similarity. This dynamic problem has been tackled in a recent paper by Singitham et al. in in VLDB 2004. Their proposed solution, which we take as baseline, is a variant of the cluster-pruning technique that has the potential for scaling to very large corpora of documents, and is far ...
The authors present tensile data and creep-rupture data out to approximately 40,000 h duration on low-carbon Alloy 800. Each of the four casts was heat treated to three conditions in tube form. When the test programme was originally conceived, the prime object was to obtain 100,000 hour design data; the programme was designed prior to some of the more recently discovered effects such as that of #gamma#' on ductility. Therefore no specific attempt was made to control to a low level, the Al and Ti contents of the casts. A subsequent programme was embarked upon in 1976 where these factors were taken into account. The bulk data obtained show many characteristics which are probably typical of the low-carbon variant of this material and both the quantity and duration of the data are a contribution to the knowledge of the long-term behaviour of this class of alloy, whose future use lies, inter alia, in nuclear applications over the temperature range for which ERA data ...
Abstract Common single nucleotide polymorphisms (SNPs) in SMAD7 (18q21) have been linked to colorectal cancer (CRC) risk in genome-wide association studies, but little is known about their effects on survival. SMAD7 regulates gastrointestinal inflammation by inhibiting transforming growth factor- (TGFB), which can act as both a tumor suppressor and a promoter of metastasis. Regular use of cyclooxygenase-2 (COX2) inhibitors, such as nonsteroidal anti-inflammatory drugs (NSAIDs), reduces the risk of developing CRC. Because COX2 overexpression reduces the growth suppressing effects of TGFB, we hypothesized that survival may depend on both SMAD7 genotype and prediagnostic NSAID use. Postmenopausal women, ages 50-74, diagnosed with incident invasive CRC from 1997 to 2002 were identified using t...
A first-principles task-based approach to the design of medical ultrasonic imaging systems for breast lesion discrimination is described. This study explores a new approximation to the ideal Bayesian observer strategy that allows for object heterogeneity. The new method, called iterative Wiener filtering, is implemented using echo data simulations and a phantom study. We studied five lesion features closely associated with visual discrimination for clinical diagnosis. A series of human observer measurements for the same image data allowed us to quantitatively compare alternative beamforming strategies through measurements of visual discrimination efficiency. Employing the Smith-Wagner model observer, we were able to breakdown efficiency estimates and identify the processing stage at which performance losses occur. The methods were implemented using a commercial scanner and a cyst phantom to explore development of spatial filters for systems with shift-variant ...
The subjects covered in this Symposium range through almost every clinical medical specialty. From an average of one paper in each of the past three Symposiums, the explosive interest in cerebral amyloidosis has led to the presentation of 12 papers on this subject in the present volume. The genetically predisposed familial amyloidotic processes, such as the polyneuropathies and familial Mediterranean fever have also stimulated extensive and intriguing investigations which have revealed the striking effect of a single amino acid substitution in transforming a normal protein into a lethal ''amyloidogenic'' one. This Symposium clearly depicts the advances since the first amyloid fibril protein was definitively identified and defined 14 years ago. Since all amyloid fibril proteins so far described are variants of normal proteins, attention to gene abnormalities now becomes a significant focus as well as the pathogenic sequences which lead in these cases to twisted ...
Shell Solar GmbH is working on a variant of the so-called stacked elemental layer process for CIGSSe absorber production. The metal films resp. the selenium are deposited on the Mb electrode at room temperature by DC sputtering (CIG) or evaporation (Se) and then processed into semiconductors by rapid thermal annealing (RTP). Currently, the mean efficiency of the pilot plant is i 12.6 {+-} 0.2 % for non-sealed 30 x 30 cm{sup 2} modules, the key efficiency is 13.0 %. In addition to the 30 x 30 cm{sup 2} pilot line, a small series of 60x90cm2 modules was constructed in December 2004. Here, the mean efficiency was 13.0 percent while the average module power was higher than 60 W. The contribution also describes investigations of ceramically sputtered n-ZnO:Al layers with reduced Al concedntrations of 1 percent and on reactively sputtered n-ZnO.Al layers from the double roller magnetron. (orig.) [German] Bei Shell Solar GmbH wird eine Variante des ...
Energy in general is essential for economic and social development, prosperity, health and security of citizens. of the other hand, world population over the last 10 years has increased by more than 12%, and now it is exactly about 6.4 billion people and it means more demand for energy. Meanwhile, global primary energy consumption has seen an increase of 20%. Energy supply has some sources and unfortunately most of them have impact on life cycle in biosphere. However, the developed countries, that are only 16% in the population in 2000, consume the energy of 80%. This article deals with the threat of global climate change and its implications throughout the world.
The #alpha# radiation dose to the lungs of people who live in buildings constructed of some granites, low density concretes, and gypsum boards is higher than for residents of most other types of dwellings due to the air-borne progeny of radon. There is evidence that sealing the interior surfaces with epoxy paint, for example, can reduce the #alpha# dose to the lung significantly without a compensating increase in whole-body exposure to the #gamma#-rays from radon progeny. Based on the incidence rates for lung cancer in uranium miners, a concentration of radon of the order of 1 to 5 pCi/l. appears to be a reasonable limit for 'lifetime' exposure indoors for 'typical' home ventilation conditions. (author).
The information given in the present report about the Chernobyl accident and its radiological consequences indicates a serious crisis of the international radiation community. The following signs of this crises can be discerned: The international radiation community did not recognize the real reasons of the accident for a long time. It could not make a correct assessment of the damage to the thyroid of the affected populations of Belarus, Russia and the Ukraine. Up to present time it rejects the reliable data on hereditary malformations. It is not able to accept reliable data on the increase in the incidence in all categories of people affected by the Chernobyl accident. The international radiation community supported the Soviet authorities in their attempts to play down the radiological consequences of the Chernobyl accident for a long time. (author)