In Experiment I, lever pressing by squirrel monkeys was maintained under a sequence of variable-interval, multiple variable-interval variable-interval, and multiple variable-interval extinction schedules...Full Text Available
PurposeIn situ fixation for mild to moderate slipped capital femoral epiphysis (SCFE) remains an acceptable treatment methodology in most centers. Satisfactory fixation results have...Full Text Available
Previous models of fault-propagation folding used kink-band geometries to approximate folding in front of propagating thrusts. However, kink-band kinematics cannot replicate the curved fold surfaces and complex strain patterns innatural and experimental fault-propagation folds, which also occur in front of steeper reverse and normal faults. Fault-propagation fold hinges tighten and converge downward, forming a triangular zone of penetrative deformation focused on the tip of the propagating fault. The downward convergence of deformation in fault-propagation folds can be modeled as triangular shear zones. Trishear, here defined as distributed, strain-compatible shear in a triangular (in profile) shear zone, provides an alternate kinematic model for fault-propagation folds. Trishear is analogous to simple shear in a tabular shear zone except that area balance in a triangular shear zone requires curved displacement oblique to the fault slip direction. Incremental ...
The gliding modes of a duplex Ti-6Al-4V titanium alloy were investigated through in situ (scanning electron microscopy) tensile tests. A method based on electron back-scattering diffraction (EBSD) measurements was used to identify activated slip systems. The approach applied to a large number of grains allowed a statistical analysis of the nature (basal, prismatic, pyramidal) and distribution of the slip systems according to the crystallographic texture. A discussion concerning the pertinence of Schmid's law to explain the occurrence and succession of slip events is then proposed. The domain in favor of each type of slip system is finally presented by using inverse pole figures mapped with Schmid's factor iso-curves.
Summary Background Current management of egg allergy relies on egg elimination from the diet. It does not protect patients from reactions after accidental ingestion of the food and it has a negative influence on quality of life. To solve these problems, some desensitization protocols have been described that are safe and effective, but only one study of a rush regimen for egg with a small patient sample has been published. Objective To evaluate the safety, efficacy and immunologic effects of an oral rush desensitization protocol for immediate egg allergy. Methods Subjects aged 5 years or older with symptomatic IgE-mediated allergy to hen's egg underwent a 5-day oral tolerance induction regimen and were subsequently maintained on a regular egg intake. The variables studied were the reaction...
For many years one of us has cooked on an induction cooktop and been impressed by its efficiency, cleanliness, and responsiveness. The commercial name ``induction'' cooktop suggests that we have here an application of Faraday's law of electromagnetic induction since the cooktop produces an oscillating magnetic field.
14C-dated Holocene coastal uplift, conventional and satellite geodetic measurements, and coseismic and aseismic fault slip reveal the pattern of distributed deformation at Taiwan resulting...Full Text Available
... 7 Page 11. Figure 5. Diffraction pattern shown a and ~ slip directions with the associated misalignment for single colonies of Ti6242 [2]. 8 Page 12. -- ...
The sterile insect release technique can often be improved by removal of females before release. Rearing efficiencies can also be increased if removal of the females occurs at early developmental stages. In order to begin to develop genetic sexing strains for the pink bollworm, Pectinophora gossypiella (Saunders), it was necessary to determine the best dosage of radiation for induction of viable sex linked recessive lethal mutations and to see if stocks containing induced sex linked lethals could be maintained in culture. Sex linked recessive lethal mutations can be detected by distorted sex ratios in the progeny of treated adults. However, in the pink bollworm, highly distorted sex ratios are common even in the absence of induced mutations. Therefore, a visible sex linked trait, purple eye, was used as a marker for the untreated X-chromosomes in crosses. Thus, the presence of a recessive sex linked lethal mutation induced by the radiation treatment may be detected ...
A quantitative description is proposed for the depletion-induced slip thickness and velocity profile of a polymer solution near the wall-fluid interface in simple shear flow. The inhomogeneous polymer density profile at a flat wall is inserted into the equations of motion for the flow of a polymer solution near the flat wall. The theory is in quantitative agreement with simulation results. (letter to the editor)
We obtained the time-lapse cumulative slip before and after the 29 November 1999, Xiuyan, Liaoning, China, Ms = 5.4 earthquake by using "repeating events" defined by waveform cross-correlation. We used the seismic waveform data from the Liaoning Regional Seismograph Network from June 1999 to December 2006. Two "multiplets" located near the seismogenic fault of the 1999 Xiuyan earthquake and the 4 February 1975, Haicheng Ms = 7.3 earthquake, respectively, were investigated. For the "multiplet" that occurred before and after the 1999 Xiuyan earthquake, apparent pre-shock accelerating-like slip behavior, clear immediate-post-seismic change, and relaxation-like post-seismic change can be observed. As a comparison, for the "multiplet" near the 1975 Haicheng earthquake which occurred a quarter century ago, the cumulative slip appears linear with a much smaller slip rate.
The purpose of this experimental study is to investigate the micromechanical fatigue behavior, in terms of slip nature and preferential cracking sites, of a commercial #alpha#/#beta#-forged Ti-6Al-4V alloy. Electron backscattering diffraction is extensively used to identify the deformation (prismatic, basal, pyramidal slip) and crack formation modes activated by fatigue at the surface of several hundred primary #alpha# nodules. Some fatal crack formation sites are also characterized. Cracking in basal planes is identified as the most critical damage mode leading to fracture. An explanation is proposed which involves the resolved shear stress, taking into account the Schmid factor and the normal stress in relation to the elastic anisotropy of the #alpha#-phase. Finally, the spatial distribution of the secondary cracks is analyzed according to the crystallographic textures (macrozones) present on a mesoscopic scale in the Ti-6Al-4V alloy.
Precipitation-hardened single crystals of a beta (bcc) Ti--40 at. percent V--1.0 at. percent Si alloy were deformed in compression at 77 and 298"0K. The dependence of the yield stress upon aging time at 843"0K for solution-treated crystals shows two maxima which are caused by silicide precipitates. The orientation dependence of the yield stress and of the active macroscopic slip plane were determined as a function of aging time. The solution-treated as well as aged crystals exhibit an asymmetry of both the yield stress and the plane of slip, the degree of asymmetry being larger at 77 than at 298"0K. The asymmetry of slip and yielding is not affected by the presence of precipitation hardening. Results indicate that the effect of the dislocation core structure on dislocation motion is independent of the presence of precipitates. (auth).
... the high current induction linear accelerator of the nanosecond range, meant to be used as injector in the collective ion accelerator, are presented. ...
Deformation mechanisms of Mg-Al-Zn (AZ31) alloys were investigated by performing tensile test at room temperature. In fine grain Mg alloys deformed at room temperature, nonbasal slip systems were found to be active as well as basal slip systems because of grain-boundary compatibility effect. Slip-induced grain-boundary sliding occurred as a complementary deformation mechanism to give rise to c-axis component of strain. With increasing grain size, the activation of the nonbasal slip systems was limited near grain boundaries. Instead of grain-boundary sliding, twinning occurred as a complementary deformation mechanism in large grained samples. Orientation analysis of twins indicated that twinning is induced by stress concentration due to the pile up of basal dislocations. The grain-size dependence on deformation mechanism was found to affect yielding behavior both microscopically and macroscopically which ...
MAGNETIC FORMING .............. MAGNETIC INDUCTION ............ MAGNETIC MATERIALS ............ MAGNETIC MEASUREMENT .......... MAGNETIC PERMEABILITY . ...
... The effectiveness of immune suppression with both 6-mercaptopurine and methotrexate was insufficient to permit induction of a clinically useful ...
A compression ignition engine was operated on dual fuel principle inducting two commercial fuels and four pure hydrocarbon fuels in turn through intake manifold along with air and injecting diesel fuel to initiate the combustion in the conventional manner. The engine was operated at different loads and at each load the quantity of inducted fuel was increased gradually till knocking set in. The engine performance and exhaust pollutant emissions were recorded at different operating conditions. It was observed that the extent of induction and the effect on the performance depend on the properties of the inducted fuel such as volatility, self ignition temperature and oxidation characteristics. The energy release during the cycle was also observed to shift depending on the properties of inducted fuel. With the dual fuel operation, the thermal efficiency at part loads was observed to be ...
Purpose. The paper introduces a novel design of air-core inductive sensors in printed circuit board (PCB) technology for a tongue control system. The tongue control system provides a quadriplegic person with a keyboard and a joystick type of mouse for interaction with a computer or for control of an assistive device. Method. Activation of inductive sensors was performed with a cylindrical, soft ferromagnetic material (activation unit). Comparative analysis of inductive sensors in PCB technology with existing hand-made inductive sensors was performed with respect to inductance, resistance, and sensitivity to activation when the activation unit was placed in the center of the sensor. Optimisation of the activation unit was performed in a finite element model. Results. PCBs with air-core indu...
There is a lot of interest in the studies that would help to understand whether there is a casual association between cancer and various types of molecular or cytogenetic damage detected in human cells. One major oncogenesis process is activation of proto-oncogenes by point mutations or chromosomal translocation. There are substantial evidence that indicates that the loss of heterozygosity of certain chromosomes is involved in human cancerogenesis. Our study aimed to elicit the possible association between cancer and DNA and cytogenetic abnormalities induced in lymphocytes of people bearing various categories of skin cancer cells. Fresh blood was collected by venipuncture from 25 individuals (including nine prior to cancer treatment). All patients were nonsmoking males, however 42.3 % of them were former smokers. Blood samples were divided into two parts and in the first part of samples cytogenetic studies were performed immediately, while from the second part lymphocytes were isolated ...
Localized deformation may play a key role in the underlying mechanism of irradiation assisted stress corrosion cracking (IASCC) in light water reactor core components. In this study, four austenitic alloys, 18Cr8Ni, 15Cr12Ni, 13Cr15Ni and 21Cr32Ni, with different stacking fault energies were irradiated to 1 and 5 dpa at 360 deg. C using 3.2 MeV protons. Interrupted constant extension rate tensile (CERT) tests were conducted in a simulated BWR environment to determine IASCC susceptibility. In order to characterize the localized deformation in slip channels and grain boundaries, parallel CERT experiments were also performed in an argon atmosphere. Results show that the IASCC susceptibility of the tested alloys increases with increasing irradiation dose and decreasing stacking fault energy. IASCC tends to initiate at locations where slip channels intersect grain boundaries. Localized deformation in the form of grain boundary sliding due to the ...
We consider the case of a test sphere (ball) of radius a{sub 1} rotating at constant angular velocity {omega} in an otherwise quiescent unbounded suspension of uniformly sized spheres of radii a{sub 2} dispersed in a Newtonian fluid of viscosity {mu}. To the first order in the volume fraction c of suspended spheres it is shown that when the ball is small compared with the suspended spheres the suspension does not behave as regards the hydrodynamic torque L exerted on the ball like a homogeneous Newtonian fluid characterized by the usual Einstein viscosity coefficient {mu}{sub s}={mu}(1+5/2c). Explicitly, the torque on the rotating sphere does not obey Kirchoff{close_quote}s law, L=8{pi}{mu}{sub s}a{sub 1}{sup 3}{omega} for no slip. Rather, a modified form of Kirchoff{close_quote}s law is obtained in which the Einstein coefficient of 5/2 is multiplied by a coefficient which is less than unity in magnitude and is functionally dependent only upon the ...
The role of phytochrome in the induction of nitrate reductase of etiolated field peas (Pisum arvense L.) was examined. Terminal bud nitrate concentration increased in darkness, and...Full Text Available
ObjectiveTo investigate the effect of maternal obesity on mode of delivery following induction of labour (IOL) for prolonged pregnancy and subsequent intrapartum and neonatal complications.DesignRetrospective...Full Text Available
AimThe goal of this study is to characterize the changes in 33 biomarkers within the gingival crevicular fluid during the 3-week induction and 4-week resolution of...Full Text Available
The effect of various hydrogen concentrations on the crystal lattice period and the hardness of titanium alloy was examined, the alloy containing about 16 at.% Mo (27.5 wt. % Mo) and having #beta# structure. The peculiar features of the mechanism of plastic deformation of the alloy were studied after adding hydrogen to it. A dependence of the crystal lattice period on the concentration of hydrogen was obtained for TixMoxH_2 alloy. It has been established that the hardness of the Ti-Mo alloy does not change when hydrogen is added to it. The presence of hydrogen introduces changes into the mechanism of deformation of #beta#-titanium alloy. The configuration of the inverse pole figures after rolling proves that the transverse slip process in an alloy with hydrogen is hampered, and that the coplanar slip process is developing in it.
Abstract: The basement of the South China Sea (SCS) and adjacent areas can be divided into six divisions (regions) - Paleozoic Erathem graben-faulted basement division in Beibu Gulf, Paleozoic Erathem strike-slip pull-apart in Yinggehai waters, Paleozoic Erathem faulted-depression in eastern Hainan, Paleozoic Erathem rifted in northern Xisha (Paracel), Paleozoic Erathem strike-slip extending in southern Xisha, and Paleozoic-Mesozoic Erathem extending in Nansha Islands (Spratly) waters. The Pre-Cenozoic basement in the SCS and Yunkai continental area are coeval within the Tethyan tectonic domain in the Pre-Cenozoic Period. They are formed on the background of the Paleo-Tethyan tectonic domain, and are important components of the Eastern Tethyan multi-island-ocean system. Three branches of t...
Because power requirements in induction heating applications are largely dependent on the physical properties of the product to be heated, inducting, heating is mainly used in steelwork applications, for the manufacture of finished or semi-finished parts. Applications here cover five main types of steelworks operation: smelting, heating prior to forming, heat treatment, surface treatment, and assembly process. At the same time, technological progress has opened up innovative applications in sectors such as chemical and agro-food industries. Other emerging applications for induction include direct forming of liquid metal, wholly or partially replacing mechanical transformations on solid metal. Techniques include electromagnetic forming, continuous cold-crucible casting, electromagnetic mixing, flow control by continuous magnetic field, and production of intense sliding fields (pumps, flow regulation). (author)
An all solid-state kicker pulser for a proton radiography system has been designed. Multiple solid-state modulators stacked in an inductive-adder configuration are utilized in this kicker pulser design. Each modulator is comprised of multiple metal-oxide-semiconductor field-effect transistors (MOSFETs) which quickly switch the energy storage capacitors across a magnetic induction core. Metglas is used as the core material to minimize loss. Voltage from each modulator is inductively added by a voltage summing stalk. A circuit model of a prototype inductive adder kicker pulser modulator has been developed to predict the performance of the pulser modulator. The modeling results are compared with experimental data.
The strain gradient crystal plasticity theory is applied to study the deformation of planar single crystal with a void under a nominally uniaxial tension. The crystal theory assumes elevated strain hardening due to slip gradients and has a constitutive length scale. The effects of the void size with respect to the constitutive length scale on the single crystal deformation are investigated.
The behaviour of an elastomeric seal for vehicle brake Tandem master cylinder is measured and analyzed in temperature and brake fluids changed. Working conditions are simulated for different piston rod velocity and cylinder supply pressure, in temperature rising, brakefluid boundary and Nanoaluminum oxide brakefluid oxide brakefluid lubrication. The result shows that Nanoaluminum oxide brakefluid with its ball shape can highly reduce friction coefficient to avoid seal excessive wear and reduce slick slip in brake applications.
The following methods of quartz ceramics alloying were considered: alloying of initial quartz glass; introduction of alloying additive into water slip of quartz glass; porous materials impregnation with salt aqueous solutions and subsequent salt thermal decomposition with formation of stable oxides in pores of ceramics. Oxygen free compounds BN, SiB_4, SiC, Si_3N_4, REM oxides and transition metal oxides were used as alloying additives. Main properties of the materials and compositions obtained are presented.
Standard SCR catalysts possess high activity for the hydrolysis of HNCO and thus explain the suitability of urea as a selective reducing agent for NO{sub x}. At high space velocities HNCO-slip can get perceptible over the entire temperature range. This can be attributed to the fact that the temperature dependence is strong for the SCR reaction, but weak for the hydrolysis reaction. (author) 3 figs., 5 refs.
We consider chemical reaction networks taken with mass action kinetics. The steady states of such a system are solutions to a system of polynomial equations. Even for small systems the task of finding the solutions is daunting. We develop an algebraic framework and procedure for linear elimination of variables. The procedure reduces the variables in the system to a set of "core" variables by eliminating variables corresponding to a set of non-interacting species. The steady states are parameterized algebraically by the core variables, and a graphical condition is given for when a steady state with positive core variables necessarily have all variables positive. Further, we characterize graphically the sets of eliminated variables that are constrained by a conservation law and show that this conservation law takes a ...
Magnetic properties of a recently developed Fe-based amorphous alloy with a high saturation induction of 1.65 T are reviewed. The increased saturation induction is fully utilized in transformers with reduced magnetic losses, physical sizes and audible noises, minimizing some of the drawbacks of amorphous metal-based transformers based on a currently available amorphous alloy. Impacts of this on the worldwide energy savings and reduction of greenhouse gas emissions are discussed. A recent effort in achieving a saturation induction beyond 1.65 T in nanocrystalline alloys is mentioned.
Tests have been conducted on a special compression ignition research engine to investigate the effects of gaseous fuels on the ignition delay in dual fuel engines. Diesel oil, n-heptane, or cetane were used as pilot fuels, and hydrogen, carbon monoxide, or methane were inducted in the intake manifold. Induction of nitrogen was used as a reference to eliminate the influence of changes in oxygen concentration and specific heats. Helium was inducted in additional tests. From the results of a number of parameter variations, the cylinder charge temperature (determined by intake temperature and compression ratio), the pilot fuel amount, and the flow of combustible gas were found to have the most significant influence on the ignition delay.
In response to stress, cells start transcriptional and transcription-independent programs that can lead to adaptation or death. Here, we show that multiple inducers of autophagy, including nutrient...Full Text Available
A device made of amorphous silicon which exhibits inductive properties at certain voltage biases and in certain frequency ranges in described. Devices of the type described can be made in integrated circuit form.
Apr 9, 2003 ... Adam Kissiah Jr., a retired KSC engineer, will be honored for his development of the digital hearing aid technology that led to the cochlear ...
... ge aircraft engines (geae) has taken to development an induction plasma deposition (ipd) processing method for the fabrication of ti6242/sic mmc ...
The effects of temperatures, durations of treatment, and derivations from spermatophores or spermaries on in vitro acrosome reaction of the spermatozoa in the Chinese mitten crab Eriocheir sinensis...Full Text Available
Synthesis of wild-type Neurospora crassa assimilatory nitrate reductase is induced in the presence of nitrate ions and repressed in the presence of ammonium ions. Effects of several...Full Text Available
This chapter consists of some points including an introduction, the basic parts of mass spectroscope device, sample introduction into the inductively coupled plasma, pneumatic nebuliser, ultrasonic nebuliser, dry gas cloud system, laser ablation unit, inductively coupled plasma-ion source, extraction of ions from ion source, mass analysis, quad-polar mass spectrometer, dual assembly mass spectrometer, mass spectrometer by calculation of time of flight, ion interferences and the ability of resolution, ion counter, working conditions of inductively coupled plasma mass spectroscope device, efficiency of ion transportation in an inductively coupled plasma mass spectroscope device and applications of analysis using mass spectroscope of induced plasma including nuclear, industrial, geological, environmental and archaeological applications, measurement of isotopes ratio and applications in tracing crimes.
Several scientists have proposed that DNA repair deficiencies and the induction of a mutator phenotype are responsible for the generation of multiple mutagenic alterations in cancer cells. I propose...Full Text Available
Canisters with spent nuclear fuel can obviously not be located within deformation zones as this might jeopardise their long term mechanical stability and thereby constitute a potential hazard to the biosphere. Less apparent, but equally important, is the fact that earthquakes trigger reactivation, slip, of structures some distance from their hypocentres due to, among many other factors, stress redistribution. Fault slip across a deposition hole might damage the isolation capacity of the canister and thereby jeopardise the overall integrity of the barrier system. Therefore, the following question might be posed: What is the distance from a deformation zone beyond which a canister can be safely emplaced? This respect distance cannot be readily computed because, unknown future events aside, there are some complicated aspects that need to be addressed e.g. degree of conservatism, scale, our ability to model ice sheets and earthquakes, etc. In this ...
The goal of this project was to demonstrate that a new low-expanding ceramic (Ca{sub 0.6},Mg{sub 0.4})Zr{sub 4}(PO{sub 4}){sub 6}, hereafter referred to as CMZP, could be used as an exhaust manifold liner in off-road diesel engines and provide improved engine efficiency (by permitting higher engine operating temperature). This study has successfully demonstrated this improvement and further engine testing (and possible manufacturing) is presently underway at Caterpillar Inc. Laboratories. Basically this program involved two subcontracts: one to Virginia Tech to develop sintering procedures for CMZP, and one to Caterpillar, Inc. to develop slip casting procedures for CMZP. Nearly 100kg of CMZP were prepared by MATVA, Inc. and Virginia Tech for use by Caterpillar. Virginia Tech developed detailed sintering procedures for CMZP and Caterpillar developed slip casting procedures and manufactured several exhaust manifold elbows. These elbows have been ...
Deformation mechanisms were investigated in fine-grain (d=7 {mu}m) AZ31 Mg alloy in order to understand their excellent room-temperature ductility. Dislocation cross slip from basal to non-basal planes was found to occur easily at room temperature at a plastic anisotropy factor of only 1.5 instead of several tens to 100 expected from the single crystal CRSS data. Enhanced grain-boundary sliding (GBS) was also found to occur at room temperature. The contribution of GBS strain was found to be approximately 8% of total strain. The enhanced activity of non-basal dislocation slip and GBS was attributed to grain-boundary compatibility effects. Moreover, dynamic recovery was found to occur during deformation at room temperature associated with the formation of recovery twins and small-angle grain boundaries. The occurrence of these deformation mechanisms at room temperature was considered to be a major reason for an excellent ductility in fine-grain ...
The purpose of this work was to investigate the role of chromium on hydrogen embrittlement of Ni-Cr-Fe alloys and thus to develop a better understanding of the low-temperature stress corrosion cracking (SCC) phenomenon. The effect of chromium on hydrogen embrittlement was examined using tensile tests followed by material evaluation via scanning electron microscopy (SEM) and light optical microscopy. Four alloys were prepared with chromium contents ranging from 6 to 35 wt pct. In the uncharged condition, ductility, as measured by the percent elongation or reduction in area, increased as the alloy chromium content increased. Hydrogen appeared to have only minor effects on the mechanical properties of the low-chromium alloys. The addition of hydrogen had a marked effect on the ductility of the higher-chromium alloys. In the 26 pct chromium alloy, the elongation to failure was reduced from 53 to 14 pct, with a change in fracture mode from mixed ductile dimple and ductile intergranular ...
A series of cyclic strain controlled tests have been carried out at 600/sup 0/C on three high temperature austenitic iron-based alloys, AISI type 316 stainless steel, Alloy 800 H and Sandvik 253 MA. The tests were carried out under constant total strain control using a constant strain rate of 0.005 s/sup -1/. By considering the changes in modulus throughout the life of each specimen it was found that damage evolution could be successfully predicted as a function of plastic strain range despite the fact that each alloy had been chosen because of a different stress response at 600/sup 0/C. Although each alloy accumulated fatigue damage in a similar manner the longer lives of Sandvik 253 MA and Alloy 800 H at a given total strain range were due to a smaller plastic strain component and a reduced stage I crack propagation rate. In the 253 MA alloy, slip was predominantly planar with some cells occasionally forming at high strain ranges. Slip was ...
Production of hydrogen sulfide in produced waters due to the activity of sulfate-reducing bacteria (SRB) is a potentially serious problem. The hydrogen sulfide is not only a safety and environmental concern, it also contributes to corrosion, solids formation, a reduction in produced oil and gas values, and limitations on water discharge. Waters produced from seawater-flooded reservoirs typically contain all of the nutrients required to support SRB metabolism. Surface processing facilities provide a favorable environment in which SRB flourish, converting water-borne nutrients into biomass and H{sub 2}S. This paper will present results from a field trial in which a new technology for the biochemical control of SRB metabolism was successfully applied. A slip stream of water downstream of separators on a produced water handling facility was routed through a bioreactor in a side-steam device where microbial growth was allowed to develop fully. This ...
Comments are made on the Public Inquiry into CEGB's proposal to construct a pressurized water reactor (PWR) at Sizewell, UK. Aspects discussed include: time elapsed and its possible effect on the result; economics of nuclear power plants compared with coal-fired power plants; changes in real sterling/dollar exchange rates; effect of mineworkers' strike; the UK electric power generating system; AGR reactors compared with PWR reactors; extension of Magnox reactor life; radioactive waste management; political decisions.
The mixed structure of a nuclear reactor building is composed of SC-columns, S-beams, S-joints and PCa-panels. Following the last report (Part 7)[1], the main test results of the mixed structure, that is, the deformation mode, strain distribution and shear strength, are described. The S-joints using ultrahigh strength materials had no buckling nor shear slipping. The proposed mixed structure resisted the external horizontal forces under integrated uniformity among SC-columns, S-joints and PCa-panels. It could be confirmed that the mixed structure can be established. (author)
Environmental studies in slip-stream process development units at SCGP-1, Shell's advanced coal gasification demonstration plant, located near Houston, Texas, have demonstrated that the gas and water effluents from the Shell Coal Gasification Process (SCGP) are environmentally benign on a broad slate of coals. This report presents the results of those environmental studies. It contains two major subjects, which describe, respectively, the experiments on gas treating and the experiments on water treating. Gas treatment focused on the performance of aqueous methyldiethanolamine (MDEA) and sulfinol-M. 8 refs., 24 figs., 13 tabs.
By treatment with beta or gamma rays, PTFE waste is converted to high-grade PTFE fine powder. High-molecular weight PTFE is degraded to low-molecular weight PTFE. Due to this the density, the degree of crystallinity, and the melt flow index are increased, which enhances the brittleness of the material. Irradiation of PTFE thus facilitates milling and makes the material pourable and free-flowing. Milled PTFE fine powder, lie PTFE plastic, combines temperature resistance, weather fastness, and chemical stability with good slip behaviour and antiadhesive properties. Areas of application for fine powder include additives for plastics, printing inks, nonstick coatings, and antifriction lacquers. (orig.).
Deformation experiments performed in-situ in the transmission electron microscope have led to an increased understanding of dislocation dynamics. To illustrate the capability of this technique two examples will be presented. In the first example, the processes of work hardening in Mo at room temperature will be presented. These studies have improved our understanding of dislocation mobility, dislocation generation, and dislocation-obstacle interactions. In the second example, the interaction of matrix dislocations with grain boundaries will be described. From such studies predictive criteria for slip transfer through grain boundaries have been developed.
The paper reports extensive analyses of the fractal geometry of cellular dislocation structures observed in Cu deformed in multiple-slip orientation. Several methods presented for the determination of fractal dimensions are shown to give consistent results. Criteria are formulated which allow the distinguishing of fractal from non-fractal patterns, and implications of fractal dislocation patterning for quantitative metallography are discussed in detail. For an interpretation of the findings a theoretical model is outlined according to which dislocation cell formation is associated to a noise-induced structural transition far from equilibrium. This allows relating the observed fractal dimensions to the stochastic properties of deformation by collective dislocation glide.
To evaluate the effect of porosity on superplasticity behavior, it is essential to use materials of similar initial grain sizes. This can be achieved by HIPing, which provides an effective way of reducing initial porosity while avoiding appreciable grain growth; various levels of porosity can be achieved for similar grain sizes. This note is concerned with the influence of porosity on superplasticity tensile deformation of a fine grained high-purity alumina doped with copper oxide and containing a grain growth inhibitor. Specimens were prepared by slip casting to net-shape and sintering; some presintered specimens were HIPed to reduce porosity. The subsequent superplasticity behavior is related to porosity in the material.
The island of Hispaniola (Dominican Republic and Haiti) lies within the North Caribbean strike-slip plate boundary zone. The post-Eocene history of Hispaniola is marked by strike-slip accretion of crustal fragments onto a Late Cretaceous-Eocene island arc. Three onshore Neogene clastic basins have been the focus of petroleum exploration in Hispaniola. Oil production was achieved by drilling surface anticlines in the Azua Basin in South-Central Hispaniola (Dominican Republic) during World War II (Maleno and Higuerito fields). More modern seismic exploration has been carried out in the Enriquillo, San Juan and Cibao Basins, but has not resulted in production. Recent surface and seismic stratigraphic mapping has elucidated the geologic history of Southern Hispaniola. It consists of several Late Cretaceous-Eocene oceanic and island-arc terranes separated by E-W to NW/SE-striking ''ramp'' or thrust-bound clastic ...
This work covers three distinct aspects of deformation and fracture during indentations. In particular, we develop an approach to verification of nanoindentation induced film fracture in hard film/soft substrate systems; we examine the ability to perform these experiments in harsh environments; we investigate the methods by which the resulting deformation from indentation can be quantified and correlated to computational simulations, and we examine the onset of plasticity during indentation testing. First, nanoindentation was utilized to induce fracture of brittle thin oxide films on compliant substrates. During the indentation, a load is applied and the penetration depth is continuously measured. A sudden discontinuity, indicative of film fracture, was observed upon the loading portion of the load-depth curve. The mechanical properties of thermally grown oxide films on various substrates were calculated using two different numerical methods. The first method utilized a plate bending ...
We present an image of the rupture propagation of the 2004 M6.0 Parkfield earthquake using records from a dense network of local strong motion stations. We back-propagate high-frequency waveforms in 3D with a method, similar to reverse time migration, to obtain an estimate of the distribution of radiated high-frequency seismic energy in space and time. The image is forced to be coherent at the known hypocenter location and the quake origin time by applying small static time shifts obtained using waveform cross-correlation. We observe that the Parkfield earthquake radiated a distinct secondary high-frequency phase, which is located about 12.5~km northwest of the hypocenter with an onset of seismic radiation about 5~s after the rupture initiation. The time history of the back-projection suggests a rupture velocity of 2.5~km/s between hypocenter and subevent. The back-projection result is confirmed by inversion of picked arrival times of the secondary event clearly visible at some of the ...
The experimental superconducting magnetic system of 0.5 MJ energy storage is described. The step variation of the winding inductance provides a control by the discharge current at the energy output on a high-ohmic load. The voltage on a load is 45 kV at the current 1100 A under the controllable discharge conditions. The energy transfer coefficient constitutes 0,76 under the maximum-to-minimal current ratio equal to 1.3. 7 refs., 3 figs., 2 tabs.
The effects of sodium ions on the uptake of Hg2+ and induction of the Tn21 mer operon were studied by using Escherichia coli HMS174 harboring the reporter plasmids pRB28 and pOS14. Plasmid pRB28 carries...Full Text Available
Ditercalinium, an antitumor bifunctional intercalator which forms a high affinity reversible complex with DNA, was found to be specifically cytotoxic for polA and lig7 E. coli strains. In the polA strain,...Full Text Available
A previous study described the basic theoretical expectations of the magnetic dipole radiation and unipolar induction of pulsars and presented observational results. This paper further discusses the difference between the two braking mechanisms and analyses the results of a statistical study through observed data of apparent beamwidth's distributions and a geometrical method. The theory of magnetic dipole radiation of pulsars agrees with the observations. Unipolar induction as a braking mechanism is not consistent with the observations.
In a positive polarity induction adder each of the induction cavities is a cathode, which emits electrons at a unique potential. These broad spectrum electrons strongly affect Magnetically Insulated Transmission Line (MITL) behavior. Electron flow decreases the cavity-to-MITL coupling efficiency, and reduces the power transport efficiency along the system. Also, the operating impedance of the MITL is lowered, reducing the diode impedance required for good coupling and good total system power efficiency. It is therefore imperative to understand the details of MITL electron flow. In previous work, measurement of MITL electron flow for a twenty-stage linear induction adder (Hermes III), operated in positive polarity, was compared with simulations. There was qualitative agreement, but some differences were noted. For example, measured electron flow in the first cavities was greater than in the simulations. The authors have ...
Attention is given to the folowing topics: population I and II variable stars; LP variables, the sun, and mass determination; and predegenerate and degenerate variables. Particular papers are presented on alternative evolutionary approaches to the absolute magnitude of the RR Lyrae variables; the evolution of the Cepheid stars; nonradial pulsations in rapidly rotating Delta Scuti stars; dynamical models of dust shells around Mira variables; and pulsations of central stars of planetary nebulae.
Investigations of radionuclide metabolism and effects in various mammalian species revealed important similarities between animals and humans and between some animal species. These include skeletal deposition of radium and radiostrontium in bone volume; deposition on bone surfaces of plutonium and other actinides; liver deposition of actinides; induction of skeletal or liver malignancies by these radionuclides; induction of tooth and jaw abnormalities; mammary cancer induction by radium in humans and in the beagle; depression of circulating cells in blood; and induction of bone fractures. There are also inter-species differences that may not have been noted if multiple species (including humans) had not been studied. Some of these are more rapid excretion of radium in humans compared with most other mammals; induction by radium of eye melanomas in animals but not humans; rapid loss ...
Objective: To find out safety and efficiency of Misoprostol in cervical ripening and induction of labour to achieve vaginal delivery. Results: From Misoprostol insertion to delivery time was 4-24 hours. Vaginal delivery was achieved in 80.2%, which included spontaneous, forceps and vacuum extraction. Caesarean section rate was 19.7%. Indications for C. Section included Misoprostol unresponsiveness 11% and fetal distress in 8.6%. Oxytocin augmentation was required in 32% of cases. Term babies were 58%. Intrauterine death and neonatal deaths were 9.8% and 8.6% respectively. Hyper stimulation and postpartum haemorrhage was seen in 2.4% and 3.7% of patients respectively. Conclusion: intravaginal Misoprostol is well tolerated and is very effective for the induction of labour in eclampsia. It helps vaginal delivery in toxemic patients, reduces maternal morbidity, mortality and hospital stay. (author)
This paper presents a new and simple method for sensorless control of matrix converter drives using a power flowing to the motor. The proposed control algorithm is based on controlling the instantaneous real and imaginary powers into the induction motor. To improve low-speed sensorless performance, the nonlinearities of a matrix converter drive such as commutation delays, turn-ON and turn-OFF times of switching devices, and on-state switching device voltage drop are modeled using a PQ power transformation and compensated using a reference power control scheme. The proposed sensorless control method is applied for the induction motor drive using a 3 kW matrix converter system. Experimental results are shown to illustrate the feasibility of the proposed strategy. Udgivelsesdato: September
To test the hypothesis that leaf level photosynthetic related traits might confer late successionals a competitive advantage over early successionals in low light growth conditions, steady photosynthetic assimilation and dynamic photosynthetic induction related traits were examined in low light grown seedlings with contrasting successional status. Compared with the early successionals, late successionals as a group significantly exhibited lower leaf gas exchange rates. While late successionals required a longer time to respond to simulated sunflecks, they had lower rates of induction losses after sunflecks. Such photosynthetic induction traits allowed late successionals to more effectively utilize subsequent sunflecks. It was observed that plants with lower gas exchange rates responded mor...
The high repetition rate and low single-pass gain inherent in an rf-driven Free Electron Laser (FEL) dictate that the laser system be configured as an oscillator. This allows the laser's electric field to build up over many passes around a high Q cavity. By way of contrast, the high-current capability of the Induction Linac (IL) system permits high single-pass optical gain, but the relatively low duty factor precludes oscillator operation; the pulses are neither long enough nor often enough to permit a field to accumulate in a cavity. The IL is thus configured as a MOPA (master oscillator/power amplifier) with a conventional laser serving as the MO. This report concentrates on the status of IL-driven FEL research at LLNL and gives a description of several applications for the high-peak-power radiation produced by an induction linac FEL.
The enzyme TEM1-b-lactamase has been used as a model to study the impact of different cultivation and induction regimes on the structure of cytosolic inclusion bodies (IBs). The protein has been heterologously expressed in Escherichia coli in fed-batch cultivations at different temperatures (30, 37, and 40degreeC) as well as induction regimes that guaranteed distinct product formation rates and ratios of soluble to aggregated protein. Additionally, shake flask cultivations at 20, 30, and 37degreeC were performed. IBs were sampled during the whole bioprocess and structural analysis was performed by attenuated total reflectance Fourier transform infrared (ATR-FT-IR) spectroscopy. This work clearly demonstrates that the tested production regimes and rates had no impact on the IB structure, wh...
Several lines of evidence are presented that indicate that the level of tetracycline resistance of Esherichia coli strains harboring plasmid pBR322 varies according to whether the SOS system of the host bacteria has been induced. These include use of strains in which the SOS system is expressed constitutively (lexA def.), is thermoinducible (recA441) or noninducible (lexA ind-), or is highly repressed (multiple copies of lexA+). Similar induction was observed with the product of another plasmid gene, beta-lactamase. The amounts of extractable plasmid DNA were also increased by SOS induction, and we propose that the SOS-induced increases in levels of tetracycline resistance and beta-lactamase activity are due to an increased plasmid copy number.
Mini-LIA is a miniature of a linear induction accelerator developed by China Academy of Engineering Physics and Tsinghua University in 2007. It has been constructed with a thermionic cathode in an electron injector and a metglas core in the induction accelerator cavities. A double-pulsed electron beam was produced for the first time in China on the Mini-LIA with a thermionic cathode in the electron gun and a metglas core in the induction accelerator cavities. A double-pulsed beam current of more than 1.1A was obtained on condition of 80 kV double-pulsed high voltage produced by pulsed power system supplying to the injector and accelerating modules. Some primary experiments for measuring the parameters of Mini-LIA has been performed, and some beam characterizations of Mini-LIA are presented. Further improvement is underway. (authors)
The first part of this article in two parts deals with the cupola furnace process regarding the energy consumption figures and efficiencies. The splitting of heat transfer into the two stages of melting and superheating makes the poor use of energy in superheating clear. For this reason the previously published idea of duplication, i.e. melting in a cupola furnace and superheating in an induction channel furnace or coreless induction furnace, has gained in interest. The last section of part I examines and compares cupola and electrode furnaces regarding the use of primary energy, where, surprisingly, roughly equal efficiencies of 20 to 25% are found for the melting processes considered.
Recent advances made in the area of amorphous and nanocrystalline alloys exhibiting high saturation inductions are reviewed. A new chemical composition was identified that achieves a saturation induction of 1.64 T in an iron-based amorphous alloy. This alloy, when used in electrical transformers, shows a much improved performance over the existing amorphous alloy. Nanocrystalline FeCoCuNbSiB alloys are found to have saturation induction levels reaching 1.7 T. These materials are suited for use in sensors and inductors carrying large currents. Some of these nanocrystalline alloys show a BH squareness ratio exceeding 90%, which can be utilized in pulse power devices. Recent developments in the applications of these materials are also pointed out.
Sesame varieties/genotypes showed a good response to radiation with gamma rays and treatments with EMS. In M_1 both gamma rays and EMS influenced germination, seedling height, survival of plants and pollen fertility/sterility, producing deleterious effects on these characters. Compared to black seeded genotypes, white seeded ones are more susceptible to radiation. Both gamma rays and EMS produced various types of morphological variations in M_2 generation. These were dwarf plant mutants, mottled and fleshy leaved mutants (sterile), fasciated stem, flower colour, altered phyllotaxy, early, uniculm, capsule size variations, multiple capsule/leaf axil, seed coat colour variations, indehiscent and semi-indehiscent type mutants. Moreover, studies on quantitative characters including seed yield revealed the induction of mutants in both positive and negative directions for such traits which made a good scope of selection of desirable mutants in M_2 generation. Mutants ...
To clarify the acidic and alkaline Intergranular Stress Corrosion Cracking (IGSCC) mechanism of thermally treated alloy 690 (alloy 690 TT) and shot peened alloy 800 (alloy 800 SP), C-ring tests were conducted in deaerated HCl solutions and in deaerated NaOH solutions at 350degC, compared with the acidic and the alkaline IGSCC susceptibilities of mill-annealed alloy 600 (alloy 600 MA), full-sensitized one (alloy 600 FS) and thermally treated one (alloy 600 TT). Grain boundary characteristics, such as chromium depleted zone and chromium carbide precipitation, were examined using modified Huey test and Transmission Electron Microscopy. Potential-pH diagram for Ni, Cr, Fe-H{sub 2}O system at 350degC was constructed and the solubilities of NiO, Cr{sub 2}O{sub 3} and Fe{sub 3}O{sub 4} were also calculated to evaluate the stability of oxide films which were formed on the surfaces of alloy 690, 800 and 600. Under the acidic condition, the IGSCC susceptibility of alloy 800 SP was high. The ...
To clarify the acidic and alkaline Intergranular Stress Corrosion Cracking (IGSCC) mechanism of thermally treated alloy 690 (alloy 690 TT) and shot peened alloy 800 (alloy 800 SP), C-ring tests were conducted in deaerated HCl solutions and in deaerated NaOH solutions at 350degC, compared with the acidic and the alkaline IGSCC susceptibilities of mill-annealed alloy 600 (alloy 600 MA), full-sensitized one (alloy 600 FS) and thermally treated one (alloy 600 TT). Grain boundary characteristics, such as chromium depleted zone and chromium carbide precipitation, were examined using modified Huey test and Transmission Electron Microscopy. Potential-pH diagram for Ni, Cr, Fe-H_2O system at 350degC was constructed and the solubilities of NiO, Cr_2O_3 and Fe_3O_4 were also calculated to evaluate the stability of oxide films which were formed on the surfaces of alloy 690, 800 and 600. Under the acidic condition, the IGSCC susceptibility of alloy 800 SP was high. The selective dissolution of Fe ...
We have investigated the transport of tritiated indole-3-acetic acid (IAA) in intact, red light-grown maize (Zea mays) coleoptiles during gravitropic induction and the subsequent development...Full Text Available
When faced with a harsh climate or inadequate food, some mammals enter a state of suspended animation known as torpor. A major goal of torpor research is to determine mechanisms that integrate...Full Text Available
The present invention relates to a method of recycling polymeric waste products into monomers and high value forms of carbon by pyrolytic conversion using an induction coupled RF plasma heated reactor.
Recommended treatment of chronic hepatitis B with interferon-α and/or nucleos(t)ide analogues does not lead to a satisfactory result. Induction of HBV-specific T cells by therapeutic...Full Text Available
BackgroundIn Pseudomonas fluorescens ST, the promoter of the styrene catabolic operon, PstyA, is induced by styrene and is subject to catabolite...Full Text Available
We have developed a method to extract and separate phytochelatins (PCs)—metal(loid) complexes using parallel metal(loid)-specific (inductively coupled plasma-mass spectrometry) and organic-specific...Full Text Available
BackgroundActivation of the signal transducer and activator of transcription 3 (STAT3) within antigen presenting cells (APCs) is linked to abnormal APCs differentiation and function....Full Text Available
Purpose: This paper reviews and reassesses the internationally accepted niches or ‘targets’ in bone marrow that are sensitive to the induction of leukaemia and primary...Full Text Available
A DNA sequence encoding the A chain of ricin toxin (RTA) from the castor bean plant, Ricinus communis, was placed under GAL1 promoter control and transformed into Saccharomyces cerevisiae. Induction...Full Text Available
A regulatory locus on the Staphylococcus aureus chromosome, designated sar, is involved in the expression of cell wall proteins, some of which are potentially important in the pathogenesis of endocarditis....Full Text Available
Rhizosphere acidification by Fe-deficient bean (Phaseolus vulgaris L.) plants was induced by trace amounts of divalent metal ions (Zn, Mn). The induction of this Fe-efficiency reaction...Full Text Available
Lifetime exposure to physical activity is an important construct for evaluating associations between physical activity and disease outcomes, given the long induction periods in many chronic diseases....Full Text Available
Carbenoxolone (CBX) is a semisynthetic derivative of the licorice root substance glycyrrhizinic acid and has been previously reported to induce only heat shock protein 70 [Hsp70, HSPA1A (the systematic...Full Text Available
Recovery of hydraulic conductivity after the induction of embolisms was studied in woody stems of laurel (Laurus nobilis). Previous experiments confirming the recovery of hydraulic...Full Text Available
Technologies for materials, processes, and manufacturing that will provide safe, .... advanced energy conversion techniques, and pulsed inductive and ... duration antimatter storage and transportation, and methods for utilizing ...... EVA systems can be found in the EVA Technology Roadmap of the EVA Project Plan. ...
A Monascus pilosus strain was selected for production of intracellular α-galactosidase. Optimum conditions for mycelial growth and enzyme induction were determined. Galactose...Full Text Available
Platelet-derived growth factor (PDGF) is a potent moderator of soft tissue repair through induction of the inflammatory phase of repair and subsequent enhanced collagen deposition. We examined the effect...Full Text Available
Effects of physical environment on plasma membrane semipermeability and osmotic induction of changes in aqueous cytoplasmic volume were studied in vegetative and spore cells of a plant pathogenic fungus,...Full Text Available
The author derives to which of the three types an irreducible UA representation which is obtained with the procedure of generalised induction belongs. The question whether or not the irreducible induced UA representations are on standardform is analysed. The results hold as well for induced PUA representations. (Auth.).
Importance of the fieldThe cytochrome P450 (CYP) isoforms that are selectively induced following exposure to structurally-diverse chemicals often are the ones capable...Full Text Available
Increased oxidative stress is associated with perinatal asphyxia and respiratory distress in the newborn period. Induction of nuclear factor erythroid 2 p45-related factor (Nrf2) has been shown to decrease...Full Text Available
The effect of different nitrogen compounds on the induction of reduced nicotinamide adenine dinucleotide phosphate-nitrate reductase was examined in Neurospora crassa. Whereas in the wild-type strain...Full Text Available
Transcriptional regulation of the galactose-metabolizing genes in Saccharomyces cerevisiae depends on three core proteins: Gal4p, the transcriptional activator that binds to upstream activating DNA sequences (UASGAL); Gal80p, a repressor that binds to the carboxyl terminus of Gal4p and inhibits transcription; and Gal3p, a cytoplasmic transducer that, upon binding galactose and adenosine 5'-triphosphate, relieves Gal80p repression. The current model of induction relies on Gal3p sequestering Gal80p in the cytoplasm. However, the rapid induction of this system implies that there is a missing factor. Our structure of Gal80p in complex with a peptide from the carboxyl-terminal activation domain of Gal4p reveals the existence of a dinucleotide that mediates the interaction between the two. Biochemical and in vivo experiments suggests that nicotinamide adenine dinucleotide phosphate (NADP) plays a key role in the initial ...
Human skin is a local source of corticotropin-releasing hormone (CRH) and expresses CRH and CRH receptors (CRH-R) at mRNA and protein levels. Epidermal melanocytes respond to CRH by induction...Full Text Available
AbstractIntrathymic expression of tissue-restricted antigens (TRAs) has been viewed as the key element in the induction of central tolerance and recently, a central role for the autoimmune...Full Text Available
The use of infectious pathogens has allowed the detection of the development of synergism between pathogens and ubiquitous environmental chemical contaminants. This synergism has been demonstrated to...Full Text Available
Somatic radiation doses are recognized to be possible factors of carcinogenesis. In correctly performed mammography, however, even as screening test, the radiation dose does not reach such an order of magnitude that the benefit of the procedure as to prevention of breast cancer is called into question.
Previous experimental data from various laboratories indicate that endotoxin of gram-negative oral microorganisms might be one of the most important bacterial products involved in bone resorption during...Full Text Available
Water samples from several ponds in Minnesota were evaluated for their capacity to induce malformations in embryos of Xenopus laevis. The FETAX assay was used to assess the occurrence of malformations...Full Text Available
During the treatment of neonatal apnea, formula-fed infants, compared to breastfed infants, show nearly three-fold increase in clearance of caffeine, a substrate...Full Text Available
Experiments were conducted to determine the dose response of rat bladder urothelium to a range of different single and fractionated intravesicular doses of the carcinogen, N-methyl-N-nitrosourea (MNU)....Full Text Available
Unless relaxation of the stringent response is achieved, all nongrowing bacteria rapidly develop resistance to autolysis induced by a variety of agents, including all classes of cell wall synthesis...Full Text Available
TCDD and other polyhalogenated aromatic hydrocarbon ligands of the aryl hydrocarbon receptor (AHR) have been classically considered as non-genotoxic compounds because they fail to be directly mutagenic...Full Text Available
Colonization of barley (Hordeum vulgare cv Salome) roots by an arbuscular mycorrhizal fungus, Glomus intraradices Schenck & Smith, leads to elevated levels...Full Text Available
The effects of an electric current on ethylene biosynthesis were investigated in cucumber (Cucumis sativus L.) fruit that were producing almost no ethylene. Direct currents at 0.5...Full Text Available
The use of Bacillus thuringiensis (Bt) endotoxins to control insect vectors of human diseases and agricultural pests is threatened by the possible evolution of resistance in major pest...Full Text Available
The induction of voltages on pipelines and railroad signal wires can be a problem when high-voltage transmission lines share the right of way. A handbook and two computer programs provide the analytic tools for utilities to avoid the problem.
The reactive airways dysfunction syndrome (RADS), the reactive upper airways dysfunction syndrome (RUDS), the sick building syndrome (SBS), and the multiple chemical sensitivity syndrome (MCS) are overlapping...Full Text Available
Electric cars can be recharged via charging stations, battery exchange, or induction cable lanes in asphalted roads. The users' wishes remain unexplored, so a number of technologies are competing in this sector.
A linear induction accelerator that produces a beam of energetic heavy ions (T -- 10 GeV, A -- 200 amu) is a prime candidate as a driver for an inertial fusion power plant. Some early perceptions were that heavy-ion drive fusion would not be cost-competitive with other power sources because of the high cost of the accelerators. However, improved understanding of the physics of heavy-ion transport and acceleration (supported by experimental results), combined with advances in accelerator technology, have resulted in accelerator design costs -- 50% of previous estimates. As a result, heavy-ion drive fusion power plants are now projected to be cost-competitive with other conceptual fusion power plants. A brief formulation of transport and acceleration physics is presented here, along with a description of the induction Linac cost optimization code LIACEP. Cost trends are presented and discussed, along with specific cost estimates for several ...
A linear induction accelerator that produces a beam of energetic heavy ions (T #approx =# 10 GeV, A #approx =# 200 am#mu#) is a prime candidate as a driver for an inertial fusion power plant. Some early perceptions were that heavy-ion driven fusion would not be cost-competitive with other power sources because of the high cost of the accelerators. However, improved understanding of the physics of heavy-ion transport and acceleration (supported by experimental results), combined with advances in accelerator technology, have resulted in accelerator design costs -- 50% of previous estimates. As a result, heavy-ion driven fusion power plants conceptual fusion power plants. A brief formulation of transport and acceleration physics is presented here, along with a description of the induction Linac cost optimization code LIACEP. Cost trends are presented and discussed, along with specific cost estimates for several accelerator designs matched to ...
The alternative sigma factor ςB of Bacillus subtilis is required for the induction of approximately 100 genes after the imposition of a whole range of stresses and...Full Text Available
Metabolic profiling analyses were performed to determine metabolite temporal dynamics associated with the induction of acquired thermotolerance in response to heat shock and acquired freezing tolerance...Full Text Available
BackgroundEscherichia coli strain EL350 contains chromosomally integrated phage lambda Red recombinase genes enabling this strain to be used for modifying the sequence...Full Text Available
Retinoic acid inducible gene I (RIG-I) is a pattern recognition receptor (PRR) responsible for detection of nucleic acids from pathogens in the cytoplasm of infected cells and induction of type I interferon...Full Text Available
Spontaneous mouse models of cancer show promise to more accurately recapitulate human disease and predict clinical efficacy. Transgenic mice or viral vectors have been required to generate spontaneous...Full Text Available
BACKGROUND: H2-histamine receptors mediate a wide range of physiological functions extending from stimulation of gastric acid secretion to induction of human promyelocyte differentiation. We have previously...Full Text Available
The cellular properties of long-term potentiation (LTP) following pairing of pre- and postsynaptic activity were examined at a known glutamatergic synapse in the leech, specifically between the pressure...Full Text Available
We introduce cyclophosphamide-induced alopecia (CYP-IA) in C57BL-6 mice as a clinically relevant model for studying the biology of chemotherapy-induced alopecia and for developing anti-alopecia drugs....Full Text Available
Autophagy is an evolutionarily conserved degradative pathway that has been implicated in a number of physiological events important for human health. This process was originally identified as a response...Full Text Available
The in planta induction of anaerobic nitrate respiration by Erwinia carotovora subsp. atroseptica in relation to the in situ oxygen status in soft rotting potato tubers...Full Text Available
BackgroundBacterial constituents, such as Gram-negative derived lipopolysaccharide (LPS), can initiate inflammatory bone loss through induction of host-derived inflammatory...Full Text Available
BackgroundThe first week of human pre-embryo development is characterized by the induction of totipotency and then pluripotency. The understanding of this delicate process will have...Full Text Available
There is increasing concern for the potential adverse health effects of human exposures to chemical mixtures. To better understand the complex interactions of chemicals within a mixture, it is essential...Full Text Available
A computer was built for use with the NRU reactor to solve the problem of Xe/sup 135/ concentrations. The effect of any changes in reactor on Xe/sup 135/ concentration can be predicted and steps taken to avoid poisoning out. An electromechanical system was used for the computer to avoid the inherent disadvantages that electronic analog computers present for problems of very long solution times. The electromechanical analog computer has a high order of reliability and contains no vaccum tubes, commutators, slip rings, relays, or aluminum electrolytic capacitors. It is insensitive to transient disturbarce. In the event of failure of components or interruption of line voltage, it will retain existing information. The computer was designed for ~ 1% accuracy in Xe/ sup 135/ concentration readings. (W.D.M.)
Liquid-liquid wetting failure is investigated in a two-dimensional Couette system with two immiscible fluids of arbitrary viscosity. The problem is solved exactly using a sharp interface treatment of hydrodynamics (lubrication theory) as a function of the capillary number, viscous ratio and separation of scale, i.e. slip length versus macroscopic scale of the system. The existence of critical velocities, above which no stationary solutions are found, is analyzed in detail in terms of the relevant parameters of the system. Comparisons with existing analysis for other geometries are also carried out. A numerical method of analysis is also presented, based on diffuse interface models obtained from multiphase extensions of the lattice Boltzmann equation (LBE). Sharp interface and diffuse interface models are quantitatively compared face to face indicating the correct limit of applicability of the diffuse interface models.
Advances in the theory and practice of stress corrosion cracking (SCC) are reviewed for the period 1965-1990. The proceedings of two landmark conferences are used as a basis for discussion: Ohio State University (1967) and Kohler, WI (1988). The discussion is developed around the following topics: metal-environment combinations, testing, fractography, metallurgical aspects, electrochemical aspects and crack chemistry, mechanisms, and prediction and mitigation. It is concluded that the main developments since 1967 are the recognition of the lack of specificity of SCC environments, the use of slow strain rate and fracture mechanics testing, quantitative SEM fractography, studies of grain boundary structure and compositions, transient electrochemistry of bare metal surfaces, measurement and modelling of crack chemistry, elaboration of several SCC models, including slip-dissolution and film induced cleavage, and mitigation by alloy development or anodic protection. ...
Abstract Suspension of solids in stirred reactor is widely used for catalytic reactions, dissolution, etc. Quality of solid suspension is an important parameter required for the reliable design, optimum performance, and scale up of the system. Quality of suspension depends on local characteristics of solid velocity and hold up profiles. The present work was focused on investigating quality of solid suspension using ultrasound velocity profiler (UVP) measurements and CFD simulations. The slip velocity measurements carried out with UVP were used to evaluate different drag correlations used in CFD simulations. Results discussed in this work would be useful for extending the applications of CFD models for simulating large stirred slurry reactors.
Defect cluster formation in 14-MeV neutron irradiated polycrystalline copper has been observed by transmission electron microscopy (TEM) and correlated with the increase in yield stress. The measurements indicate that the radiation hardening component of the yield strength in polycrystals is not directly additive to the unirradiated yield strength. A transitional behavior was observed for radiation hardening at low fluences, which produces an anomalous variation of the defect cluster barrier strength with fluence. The behavior is attributed to the effect of grain boundaries on slip band transmission. An upper limit for the room temperature barrier strength of defect clusters in neutron-irradiated copper was determined to be #alpha#=0.23. (orig.).
A 206-size hybrid (ceramic/steel) cylindrical roller bearing was tested in MIL-L-23699 C oil at several speeds and loads. Heat-generation data was collected and subsequently correlated with bearing-analysis software. Bearing-cage slip data was also collected at various oil-flow rates, oil temperatures, and with both MIL-L-7808 J and MIL-L-23699 C oils. The hybrid bearing was tested in MIL-L-23699 C oil for for 25 hours at 2220 N radial load and 1.08 MDN shaft speed. The hybrid bearing technology demonstrated in the report is applicable to the Integrated High Performance Turbine Engine Technology Initiative. 15 refs.
In the early 1980s, a program was begun to evaluate the oil shale resources of the Albert Formation by undertaking a geological lithofacies study of the Albert strata in the Moncton Subbasin of southeastern New Brunswick. Most rock exposures of the Albert were examined from 1982-84 and additional field work was carried out in the summers of 1989 and 1990. In January 1989, 1,900 km of Vibroseis seismic reflection profiles shot from 1981-84 by Chevron Canada Resources Ltd. in the Moncton and Sackville subbasins became publicly available. This report gives the results of the geological investigations on the Albert Formation in the southeastern Moncton Subbasin and the integration of interpreted seismic reflection profiles to help resolve some of the geological problems encountered.
Landslides on ancient embankments, burial mounds of Imashiro-zuka and Nishimotome-zuka, induced by historical earthquakes related to the tectonic movement of active fault systems located between northern Osaka and Kobe, are discussed. The geological conditions of the foundation of the mounds, the lithology, stiffness, and the position of the mound relative to the fault systems, contributed to the collapse of the mounds. Obvious interior structures of landslides revealed the inherent deformation process, and provided significant insight into landslide mechanisms. Rapid increasing pore water pressure was necessary to facilitate sliding along the almost horizontal slip surfaces developed in the main part of the landslide bodies on the Imashiro-zuka mound. Liquefaction analysis using both the ...
Turbulent shear flows on shallow continental shelves (here shallow means that the interaction with the solid, no-slip bottom is important) are of great importance because tide- and wind-driven flows on the shelf are drivers of the transfer of momentum, heat, and mass (gas) across the air?sea interface. These turbulent flows play an important role because vertical mixing and current are vectors for the transport of sediment and bioactive material on continental shelves. Understanding the dynamics of this class of flows presents complications because of the presence of a free surface and also because the flow can be driven by a pressure gradient (a tidal current), a stress at the free surface (a wind-driven current), or a combination of both. In addition, the flow can be modified by the pres...
In this study we discuss an unsteady free convection MHD flow past semi-infinite vertical porous plate. We have considered the flow in the presence of a strong magnetic field and therefore the electromagnetic force is very large. This brings in the phenomenon of Hall and Ion-slip currents. The effects of these two parameters together with that of viscous dissipation and radiation absorption among others on velocity, temperature and concentration profiles are presented. The profiles are presented graphically. As the partial differential equations governing this problem are highly non-linear they are solved numerically by a finite difference method. It is found that in presence of heating of the plate by free convection current the velocity boundary layer thickness decreases.
In this study we discuss an unsteady free convection MHD flow past semi-infinite vertical porous plate. We have considered the flow in the presence of a strong magnetic field and therefore the electromagnetic force is very large. This brings in the phenomenon of Hall and Ion-slip currents. The effects of these two parameters together with that of viscous dissipation and radiation absorption among others on velocity, temperature and concentration profiles are presented. The profiles are presented graphically. As the partial differential equations governing this problem are highly non-linear they are solved numerically by a finite difference method. It is found that in presence of heating of the plate by free convection current the velocity boundary layer thickness decreases.
The grain size dependence of the tensile properties and the deformation mechanisms responsible for those properties are examined for Mg alloy, AZ31B, sheet. Specifically, the Hall-Petch effect and strain anisotropy (r-value) are characterized experimentally, and interpreted using polycrystal plasticity modeling. {1 0 . 2} extension twins, {1 0 . 1} contraction twins, and so-called 'double-twins' are observed via microscopy and diffraction-based techniques, and the amount of twinning is found to increase with increasing grain size. For the sheet texture and tensile loading condition examined, {1 0 . 2} extension twinning is not expected, yet the polycrystal plasticity model predicts the observed behavior, including this 'anomalous' tensile twinning. The analysis shows that the Hall-Petch strength dependence, of the polycrystal as a whole, is primarily determined by the grain size dependence of the strength of the prismatic slip systems.
The experimental results of brittle/ductile two-layer analogue models verify that intraplate tectonic deformation in central-eastern Asia is controlled mainly by the netlike plastic-flow (NPF) occurring in the lower lithosphere, including the lower crust and lithospheric mantle. The ductile lower layer in the model, corresponding to the lower lithosphere in the natural prototype, is made of a mixture of gum rosin and turpentine oil and the brittle upper one, to the upper crust, is formed by the consolidation of talc-powder slurry. The NPF hypothesis for continental dynamics can be regarded as a combination and development of two kinds of seemingly mutually exclusive ones, which are based on the theories of slip-line field and viscous (plastic) flow, respectively. In contrast to "homogeneou...
AZ31 Mg alloy samples were extruded by an equal channel angular extrusion (ECAE) process and subsequently annealed to obtain fine-grained material with a low dislocation density. Tensile tests at room temperature exhibited an apparent steady-state deformation region and a large tensile elongation of 47%. The deformed microstructure at an elongation of 2% indicated a substantial cross-slip to nonbasal planes possibly induced by grain-boundary compatibility effects. The nonbasal segments of dislocations were found to consist of 40% of the total dislocation density at a yield anisotropy factor of only 1.1 instead of an expected value of 100 from single-crystal experiments. (orig.)
In this paper, a complete solution of the steady-state Newton-Euler equations describing the motion of the balls in high speed thrust bill bearings is presented. Kinematic equations are derived and used as ancillary equations to obtain the numerical solution of the Newton-Euler equations. This differs from previously reported work where extraneous assumptions (instead of kinematic analysis) are used to allow solutions of these equations. It is shown that the no-slip condition for the ball motion reported in the literature is based on an unnecessary assumption. The correct form of the condition is developed and used in the analysis of the ball motion. The analysis shows the importance of contact angle on both ball motion and contact force. An approximate theory is then developed for determining the optimum contact angle that would result in minimum contact force in high speed ball bearings. The results are compared with experimental data, and theory is illustrated ...
Charged particle beams in circular accelerators couple with their surroundings through induced electromagnetic fields. This interaction can be described by so-called coupling impedances. In the frequency domain the impedance in connection with the bunch spectrum allows for stability analysis and estimates. However, for simulation codes one usually needs the wakefunction, the equivalent of the impedance in time domain. Recently the transverse impedance of a cylindrical pipe with arbitrary surface impedance was given by L. Vos. An expression for the wakefunction of this transverse resistive wall impedance with inductive bypass is derived here.
Rotary furnaces are a well established alternative to cupola furnaces. Recent innovations in oxygas furnaces have made them the preferred choice even over medium-frequency electric furnaces in many European foundries. The article explains in what respects the rotary furnace is a new iron smelting concept, as different from the cupola furnace as the medium-frequency electric furnace. (author)
A study was conducted on diesel engines to find out the effect of induction rate of biogas on engine performance indices. The results of dual fuel engine performance was compared with diesel mode for various levels of biogas induction rate (0.3 to 7.2 l/s) engine load (20% to full load) and injection timing (20.6 to 48 before top dead centre). At full and 80% brake load, the best energy mix between diesel and biogas was 1.5:1 and 4:1 respectively. (author). 7 refs., 7 figs., 4 tabs.
Correct prediction of the fission products inventory in irradiated nuclear fuels is essential for accurate estimation of fuel burnup, establishing proper requirements for spent fuel transportation and storage, materials accountability and nuclear forensics. Such prediction is impossible without accurate knowledge of neutron induced fission yields. The uncertainty of the fission yields reported in the ENDF/B-VII.0 library is not uniform across all of the data and much of the improvement is desired for certain fissioning isotopes and fission products. We discuss our measurements of cumulative fission yields in nuclear fuels irradiated in thermal and fast reactor spectra using Inductively Coupled Plasma Mass Spectrometry. (author)
Correct prediction of the fission products inventory in irradiated nuclear fuels is essential for accurate estimation of fuel burnup, establishing proper requirements for spent fuel transportation and storage, materials accountability and nuclear forensics. Such prediction is impossible without accurate knowledge of neutron induced fission yields. The uncertainty of the fission yields reported in the ENDF/B-VII.0 library is not uniform across all of the data and much of the improvement is desired for certain fissioning isotopes and fission products. We discuss our measurements of cumulative fission yields in nuclear fuels irradiated in thermal and fast reactor spectra using Inductively Coupled Plasma Mass Spectrometry.
Results obtained on induced current and voltage caused by a high voltage transmission lines running parallel at a trolley bus contact lines, are presented. A computer program in Basic language, was developed to calculate the electric induction, problems of safety, a theoretical development and mathematical model of the electric factors between two lines (inductor and induced) are also discussed. 11 figs., 1 tab., 8 refs.
The rate of hepatic cytochrome P450 Cypla1 and Cyp1a2 induction was investigated in C57BL male mice during induction with o-aminoazotoluene (OAT), benzo[a]pyrene (BP) and 1,4-dihydroxyanthraquinone (AQ). The Cypla1 mPNA level determined by quantitative RT-competitive PCR increased more than three orders of magnitude during induction with OAT and BP compared with untreated animals and remained unchanged during induction with AQ. The Cypla2 mRNA level was only 8.5, 18.7 and 1.9 times higher during induction with OAT, BP and AQ respectively than in untreated mice. At the same time 7-Ethoxyresorufin-O-deethylase (EROD) and 7-Methoxyresorufin-O-demethylase (MROD) activities of Cypla were also investigated in liver. The increase of Cypla1 mRNA level correlated with the increase of EROD activity. This suggests involvement of the transcriptional mechanism of the inducibility of this enzyme. ...
The main problems with the use of neat vegetable oils in diesel engines are higher smoke levels and lower thermal efficiency as compared to diesel. The problem can be tackled by inducting a gaseous fuel in the intake manifold along with air. In this investigation, hydrogen is used as the inducted fuel and rubber seed oil (RSO), rubber seed oil methyl ester (RSOME) and diesel are used as main fuels in a dual fuel engine. A single cylinder diesel engine with rated output of 4.4 kW at 1500 rpm was converted to operate in the dual fuel mode. Dual fuel operation of varying hydrogen quantity with RSO and RSOME results in higher brake thermal efficiency and significant reduction in smoke levels at high outputs. The maximum brake thermal efficiency is 28.12%, 29.26% and 31.62% with RSO, RSOME and diesel at hydrogen energy share of 8.39%, 8.73% and 10.1%, respectively. Smoke is reduced from 5.5 to 3.5 BSU with RSOME and for RSO it is from 6.1 to 3.8 BSU ...
A common property of aging in all animals is that chronologically and genetically identical individuals age at different rates. To unveil mechanisms that influence aging variability, we identified markers...Full Text Available
Variability in motor performance decreases with practice but is never entirely eliminated, due in part to inherent motor noise. The present study develops a method that quantifies how performers...Full Text Available
BackgroundDue to the increased accuracy of Copy Number Variable region (CNV) break point mapping, it is now possible to say with a reasonable degree of confidence whether a gene...Full Text Available
Operation of an X-ray spectrometer based on a spherical variable-line-spacing (VLS) grating is analyzed using dedicated ray-tracing software allowing fast optimization of the grating parameters and...Full Text Available
Background/AimsTo explore different definitions of intra-individual variability (IIV) to summarize performance on commonly utilized cognitive tests (Mini Mental State Exam; Clock...Full Text Available
This work reports the design of and experimentation with a topographically patterned cell culture substrate of variable local density and anisotropy as a facile and efficient platform to guide...Full Text Available
BackgroundVariable platelet response to clopidogrel has been widely observed. Studies have shown that the mean aggregation response to clopidogrel can be changed...Full Text Available
BackgroundIn cancer research, most clinical variables have already been investigated and are now well established. The use of transcriptomic variables has raised two problems: restricting...Full Text Available
A common approach used to fuse simultaneously recorded EEG and fMRI is to correlate trial-by-trial variability in the EEG, or variability of components derived therefrom, with the blood oxygenation...Full Text Available
Recent developments in the analysis of Mira atmosphere, the determination of the pulsation mode, the problem of mass loss, and the evolution of the Mira variables are covered. Model atmospheres for Mira variables, including the opacities of the molecules expected in very late M-type atmospheres are discussed. The pulsation constant for Omicron Ceti is evaluated using T(eff) = 2900 + or - 200 K, and it is concluded that Miras are fundamental mode pulsators. The importance of molecular opacity to the driving of mass loss is evaluated, and it is pointed out that the radiation pressure on molecules is not a major factor in driving mass loss from Mira. Mass loss is considered as a factor in the calculations of the periods for Mira variables. 30 refs.
A theory of the asymptotic functions for the case of many variables is presented. It is shown that the class F(R"N) of these generalized functions is closed in respect to the linear algebraic and analytic operations, multiplication as well as a set of linear and polynomial changes of the variables. The existence in F(R"N) of analogues (consistent with the linear operations) of the Schwartz distributions with point support is proved. In terms of these analogues, some formulae for singular products and changes of variables of the Dirac #delta#-function and its derivatives #delta#"("i")(x), x is an element of R"N, are given. (author). 14 refs.
Success in improving hydropower project efficiency has opened more global markets for variable-speed generator technology. Manufacturers continue to test the markets as the technology evolves. The potential of variable-speed application becomes evident considering that more than 150 pumped storage plants, with a combined capacity exceeding 100,000 MW, are in operation globally.
Based on proposed models for the tidal spin-up and magnetic braking of stars with a convective outer envelope, it is suggested that the rotation of secondaries in cataclysmic variables is not necessarily synchronized with the orbital revolution. This may provide an explanation for the observed large range in the mass transfer rate (at the same orbital period) of cataclysmic variables above the period gap. (author).
In this paper, we derive the moderate deviation principle for stationary sequences of bounded random variables with values in a Hilbert space. The conditions obtained are expressed in terms of martingale-type conditions. The main tools are martingale approximations and a new Hoeffding inequality for non adpated sequences of Hilbert-valued random variables. Applications to Cramer-Von Mises statistics, functions of linear processes and stable Markov chains are given.
This paper examines how robust economic, political, and demographic variables are related to water and air pollution. Employing Bayesian Averaging of Classical Estimates (BACE) for a cross section of 47 countries, 34 variables and 3 proxies for air and water pollution over a period from 1980 to 2000 we confirm the environmental Kuznets curve hypothesis and highlight the relevance of variables that are not directly related to production.
In recent years there has been a renewed interest in the treatment of quantum mechanics in terms of joint distribution functions, i.e. functions of momentum and position coordinates p and q. The author considers j.d.f. in the sense of classical probability theory of a stochastic variable. The j.d.f. is then interpreted as the probability that the variables p and q have certain values, the variables being considered as a property possessed by the object system. This formalism is used to provide a unified description of bradyons and tachyons. (Auth.).
The authors summarize EUVE's contribution to the study of the boundary layer emission of high accretion-rate nonmagnetic cataclysmic variables, especially the dwarf novae SS Cyg, U Gem, VW Hyi, and OY Car in outburst. They discuss the optical and EUV light curves of dwarf nova outbursts, the quasi-coherent oscillations of the EUV flux of SS Cyg, the EUV spectra of dwarf novae, and the future of EUV observations of cataclysmic variables.
Respiration and related physiologic variables in different tissues of Barytelphusa guerini and the respiration of this freshwater crab as a whole are closely synchronized in phase and in frequency along the circadian scale, in the face of large differences in circadian amplitude. A very close timing of most of the 36 variables examined in 2 separate circadian profiles and a modulation of some of these variables in added profiles as a function of lunar stage are clearly demonstrable, statistically significant and illustrative of time relations at 2 interacting frequencies. PMID:6745009
We study the surface and interface roughness of a two-liquid film system using neutron reflectometry. The middle phase and bottom phase are extracted from a three-phase microemulsion containing 2 wt% non-ionic surfactant C{sub 10}E{sub 4}, 81 wt% D{sub 2}O and 17 wt% octane (C{sub 8}H{sub 18}). The system is formed by spreading a few drops of the middle phase of the microemulsion on the bottom phase of the microemulsion. The middle phase does not wet the bottom phase, but demixes to form a top octane-water mixture layer with a thickness of {proportional_to}580 A. The mean surface roughness of the system is found to be 7 A but the data are insensitive to interface roughness. An extended capillary wave model for a two-liquid-film system is derived to account for the coupling between the surface and interface. The dispersion relation yields two fundamental modes. In a calculation of mean-square roughness (left angle {zeta}{sup 2} right angle {sup 1/2}) a high-k-cutoff is needed to account ...
The fine scale mechanical probing capability of NI-AFM was used to examine hydrogen interaction with plasticity. To realize this, an electrochemical three electrode setup was incorporated into the NI-AFM. The developed ECNI-AFM is capable of performing nanoindentation as well as imaging surfaces inside electrolytes. The developed ECNI-AFM setup was used to examine the effect of cathodically charged hydrogen on dislocation nucleation in pure metals and alloys. It was shown that hydrogen reduces the pop-in load in all of the tested materials except Cu. The reduced pop-in load can be interpreted as the HELP mechanism. Classical dislocation theory was used to model the homogeneous dislocation nucleation and it was shown that H reduces the activation energy for dislocation nucleation in H sensitive metals which are not undergoing a phase transformation. The activation energy for dislocation nucleation is related to the material specific parameters; shear modulus {mu}, dislocation core ...
A methodology and hypothetical case study are presented for incorporation of uncertainty and variability into calculations of human health risk appropriate for regional, or basin-scale, groundwater management problems. Uncertainty in well water concentration is introduced through complex contaminant migration patterns in the subsurface. Variability is considered in parameters related to individual behavior patterns and biological effects and to groundwater extraction and distribution networks. A joint uncertainty and variability (JUV) analysis is used to generate a two-dimensional distribution or risk surface that spans both transport uncertainty as well as individual variability. Cuts in this distributional surface (fractiles of variability and percentiles of uncertainty) are presented and discussed. Comparisons with alternative approaches based upon deterministic transport models ...
Power output of a hydrogen-diesel dual-fuel engine is limited by the onset of knock as the percentage of heat input derived from hydrogen increased beyond a certain limit. Earlier work carried out at the Internal Combustion Engines Laboratory, Indian Institute of Technology, Madras, indicates that this knock sets in when the induced hydrogen exceeds about 60% of input energy at a pilot diesel quantity of 30% of full load diesel amount. At higher rates of hydrogen induction, the richer hydrogen-air mixture is more prone to knocking. Hardly any information is available on the possibilities of improving the knock limited power output of a hydrogen-diesel dual-fuel engine. Water can serve as a powerful internal coolant in decreasing the unburned mixture temperature because of its high latent heat. This paper presents the results of our investigation on improving the knock limited power output when water is inducted with the intake charge of a ...
This paper presents a technique for speed control three-phase induction motor using the pulse width modulation (PWM), in open loop while maintaining the tension for constant frequency. The technique is adapted from a thesis entitled 'Control of the three-phase induction motor, using discrete PWM generation, optimized and synchronized', where studies are presented aimed at their application in home appliances, to eliminate mechanical parts, replaced by low cost electronic control, thus having a significant reduction in power consumption. Initially the experiment was done with the Intel 80C31 micro controller. In this paper, the PWM modulation is implemented using a PIC micro controller, and the speed control kept a low profile, based on tables, synchronized with transitions and reduced generation of harmonics in the network. Confirmations were made using the same process of building tables, but takes advantage of the program of ...
Ethidium bromide (EB) and ultraviolet light (UV) in combination are known to produce a synergistic induction of 'petite' mutants in yeast. Two other agents were combined with EB, 3-Carbethoxypsoralene (3 CPs) activated by 365 nm light or #gamma# rays. EB in combination with 3 CPs also resulted in an enhanced production of 'petite' mutants. After the photoaddition of 3 CPs in exponential phase cells, recovery of the 'petite' mutation during dark liquid holding was inhibited by the presence of EB producing an enhanced number of 'petite' mutants. The behavior of mitochondrial antibiotic resistance markers after individual and combined treatments with EB and 3 CPs indicates a random loss of markers after EB and a preferential loss of a certain region for the 3 CPs photoaddition. The combination of the two agents leads to an additivity of total drug marker losses rather than a synergistic loss. The combination of EB with #gamma# rays produced no enhancement in 'petite' ...
A technique and a particular apparatus for an inductive measurement of critical currents as a function of temperature and magnetic field in thin-film superconductors are described. The technique has been found to be particularly useful for high-field A-15 compounds 2 to 3 ..mu..m thick. Samples with lower critical current densities would have to be correspondingly thicker to measure over the same broad range of temperature and field. The design of the apparatus is detailed showing that the film can be taken directly from the deposition chamber and mounted without electrical contacts so samples can be changed easily. The principles of operation are developed based on the Critical State Model. These principles are tested by measurements which verify that the measured value of critical curent is independent of the amplitudes and frequency of the small ac magnetic field which is added to a much larger quasistatic field. The inductive measurements ...
The addition of paraquat (methyl viologen) to a growing culture of Escherichia coli K-12 led within 1 hr to a 10- to 20-fold increase in the level of endonuclease IV, a DNase for apurinic/apyrimidinic sites. The induction was blocked by chloramphenicol. Increases of 3-fold or more were also seen with plumbagin, menadione, and phenazine methosulfate. H_2O_2 produced no more than a 2-fold increase in endonuclease IV activity. The following agents had no significant effect: streptonigrin, nitrofurantoin, tert-butyl hydroperoxide, #gamma# rays, 260-nm UV radiation, methyl methanesulfonate, mitomycin C, and ascorbate. Paraquat, plumbagin, menadione, and phenazine methosulfate are known to generate superoxide radical anions via redox cycling in vivo. A mutant lacking superoxide dismutase was unusually sensitive to induction by paraquat. In addition, endonuclease IV could be induced by merely growing the mutant in pure O_2. The levels of endonuclease ...
Experimental and theoretical research has been conducted jointly at the Livermore and Los Alamos National laboratories on dc electromagnetic railgun Lorentz accelerators. Pellets weighing a few grams to tens of grams have been launched at velocities up to better than 11 km/s. The research is addressed to attaining repeated launches of samples at hypervelocity in target impact experiments. In these experiments, shock-induced pressures in the tens of megabars range are obtained for high pressure equation-of-state research. Primary energy sources of the order of several hundred kJ to a MJ and induction currents of the order of 1 or more MA are necessary for these launches. Erosion and deformation of the conductor rails and the accelerated sample material are continuing problems. The heating, stress, and erosion resulting from simultaneous imposition of rail induction current, dense plasma (armature) interaction, current distribution, magnetic ...
Model construction of the laboratory scale superconducting fault current limiter circuit (SFCL) has been performed. The SFCL is fault current limiter and used as electric network security. It mainly consists of a copper coil, a superconducting ring and an iron core that are concentrically arranged. The SFCL circuit is essentially a transformer where the secondary windings are being replaced by the ring of YBa_2Cu_3O_7_-_x superconductor (HTS). The ring has critical transition temperature Tc = 92 K and critical current Ic = 3.61 A. Characterization of the SFCL circuit is simulated by ANSYS version 5.4 software. The SFCL circuit consists of load and transformer impedances. The results show that the inductions of magnet field flux in the iron core of primer windings and ring disappear to one other before fault state. It means that impedance of the transformer is zero. After the condition a superconductivity behavior of the ring is disappear so that the impedance of ...
In response to a heat shock, the yeast Saccharomyces cerevisiae undergoes a large increase in its resistance to heat and, by the induction of its recombinational DNA repair capacity, a corresponding increase in resistance to radiation. Yeast which lack mitochondrial DNA, mitochondria-controlled protein synthetic apparatus, aerobic respiration, and electron transport (rho/sup 0/ strain) were used to assess the role of O/sub 2/, mitochondria, and oxidative processes controlled by mitochondria in the induction of these resistances. We have found that rho/sup 0/ yeast grown and heat shocked in either the presence or absence of O/sub 2/ are capable of developing both radiation and heat resistance. We conclude that neither the stress signal nor its cellular consequences of induced heat and radiation resistance are directly dependent on O/sub 2/, mitochondrial DNA, or mitochondria-controlled protein synthetic or oxidative processes.
OBJECTIVE:- To determine the effectiveness and safety of short-term treatment of infliximab (IFX) in a group of Chinese patients with active Crohn's disease (CD). METHODS:- Patients with established diagnosis of active CD were treated with IFX intravenously with a dose of 5-mg/kg at week 0, 2, 6. Clinical assessments were performed at baseline (week 0) and every week after IFX infusion until 8 weeks after the induction dose. RESULTS:- Fourteen patients (nine male, five female) with a mean age of 29.7 years (range from 15 to 65 years) were included in the analysis. The mean subjective scores were decreased from 2.85--0.57 at baseline to 1.3--0.4 at week 14 (P-CONCLUSIONS:- Treatment with three infusions of IFX at a dose of 5-mg/kg was effective for induction of remission for active CD patie...
In defining criteria for good protection against ionizing radiation, it is important to assess quantitatively the likely risk of any radiation exposure. The 'somatic' risks to the individual result mainly from induction of cancer in the organs irradiated, and these risks can now be estimated on the basis of numerous detailed epidemiological surveys of exposed human populations. Estimates of the risk of hereditary effects, from genetic changes induced in germ cells, are based largely on the frequency with which such effects are induced in other species. In both cases the risk at very low dose can be inferred using knowledge of the way in which radiation damage is caused in tissues. Coherent systems of radiation protection are based on a restriction of doses to the whole body and to individual organs, such that the induction of cancer and genetic harm is infrequent, and the threshold dose for causing other, 'non-stochastic', effects is not ...
We present the design, analysis, and results of the high brightness electron beam experiments currently under investigation at Sandia National Laboratories. The anticipated beam parameters are the following: energy 12 MeV, current 35 endash 40 kA, rms radius 0.5 mm, and pulse duration 40 ns full width at half-maximum. The accelerator is SABRE, a pulsed linear inductive voltage adder modified to higher impedance, and the electron source is a magnetically immersed foilless electron diode. 20 endash 30 T solenoidal magnets are required to insulate the diode and contain the beam to its extremely small-sized (1 mm) envelope. These experiments are designed to push the technology to produce the highest possible electron current in a submillimeter radius beam. Design, numerical simulations, and experimental results are presented. copyright 1997 American Institute of Physics.
Allogeneic stem-cell transplantation (SCT) is potentially curative therapy in AML by providing both dose-intensive chemo-radiotherapy and induction of graft-versus-leukemia (GvL) effect. Historically, more emphasis was given to the intensity of conditioning. Over the last decade the pendulum turned more towards induction of GvL as the primary goal. A plethora of non-myeloablative (NMA) and reduced-intensity conditioning regimens (RIC) were introduced trying to reduce transplant-related toxicities and allow SCT in elderly and medically infirm patients. In addition, reduced-toxicity myeloablative regimens (RTC) based on fludarabine and myeloablative alkylating-agent doses were designed to allow safer administration of dose-intensive therapy. Conditioning dose-intensity is highly correlated w...
Synergism has been observed during inhibiting initiated oxidation of styrene or tetralin by organic phosphites in the presence of complex compounds of some transition metals. The results are given of non-additive intensification of antioxidative activity of triphenylphosphite (TPP) and tri-(4-methyl-6-tert.-- butyl)-phenyl-phosphite (TMBP) in the process of initiated oxidation of styrene or tetralin with addition of acetylacetonates of cobalt and vanadyl. During styrene oxidation, inhibition of the reaction with chelate complex of vanadyl is weakened considerably when phosphite is added into the reaction system. During tetralin oxidation, postcatalytic (or branched) oxidation is observed only for large concentration of vanadyl complex. Addition of TPP to above complex sharply increases the induction period. When the induction period is completed, oxidation of tetralin follows the mechanism of usual, i.e. initiated, reaction.
In this article a production method of a magnetorheological suspension composed with silicon steel particles of size 0.1-0.15 mm and 4% silicon content is described. Steel particles were dispersed in a conducting carrier of a by mixture of graphite particles with size 2-5 {mu}m and cedar wood oil. The filling factor of the suspension with the silicon steel particles and with graphite particles amounted to 0.25-0.40. Samples of this suspension were placed in a rectangular vessel with electrodes and used for the investigation of the Hall effect in magnetic field with induction 0-8 T, generated by Bitter-type magnet. A non-linear dependence of Hall voltage on the induction of the applied magnetic field and a hysteresis loop of this voltage in the shape of inclined digit eight were found. The causes of the observed effects is the ordering of silicon steel particles and graphite particles along the side of magnetic field lines.
The effects of spin diffusion on the free induction decay (FID) of protons associated with the noncrystalline domains of two polymers, polyethylene and blended Nylon 66 (ZYTEL-408), have been examined using Goldman--Shen NMR pulse sequence ((1/2)..pi..x-t/sub 0/-(1/2)..pi..x-bar-tau-(1/2)..pi..x-t). At tau< or approx. =100 ..mu..s, the FID is drastically distorted from the exponential form while at longer tau(tau> or approx. =500 ..mu..s) an exponential FID is observed; but its transverse spin relaxation rate is smaller than that of the FID obtained after a single (1/2)..pi..x pulse and approaches this value at the limit of large tau. These findings are interpreted in terms of the theory of rapid spin diffusion. The spatial variation in the spin relaxation rate within the noncrystalline domain is inferred.
A new method for analysis and design of smoothing reactances utilising two-dimensional planar models is presented in this paper. Inductance and magnetic flux density are calculated, and their results compared with those measured experimentally. The results obtained are good if compared with those measured once the machine have been built. Moreover, the method herein developed is applied to the calculation of air gap lengths in terms of the desired current and inductance. The kind of reactances studied presents windings in both limbs and air gaps in the four corners (joint of limbs and yokes). The main contribution of this paper is the presentation of a method of industrial application, to be easily developed, with a very important reduction in the time of machine calculation (due to the decrease in the number of nodes and elements compared with the three-dimensional model) for the determination of the air gap length in smoothing reactances. ...
Finding interesting rule in the sixth strategy step about threshold control on generalized relations in attribute oriented induction, there is possibility to select candidate attribute for further generalization and merging of identical tuples until the number of tuples is no greater than the threshold value, as implemented in basic attribute oriented induction algorithm. At this strategy step there is possibility the number of tuples in final generalization result still greater than threshold value. In order to get the final generalization result which only small number of tuples and can be easy to transfer into simple logical formula, the seventh strategy step about rule transformation is evolved where there will be simplification by unioning or grouping the identical attribute. Our approach to measure interesting rule is opposite with heuristic measurement approach by Fudger and Hamilton where the more complex concept hierarchies, more ...
Carcinogenesis is now generally recognized to be an important detrimental effect in man after low dose irradiation. The carcinogenic action of ionizing radiation is clearly demonstrated after exposure to relatively high doses (in excess of 0.5 Gy) but for lower dose levels reliable direct observations are not available. With the introduction of special protocols for the performance of large scale screening programs by mammography the average absorbed dose in glandular tissue in the average breast can be restricted to a value of 3 mGy per mammogram. The risk for tumor induction after exposure to these low doses can never be established from human epidemiology. In order to investigate the risk of repeated exposure to small dose of ionizing radiation the induction of mammary tumors has been investigated in rats of the WAG/Rij strain after single and fractionated irradiations with gamma-rays. (author). 8 refs., 3 figs.
Maintenance of genomic integrity in embryonic cells is pivotal to proper embryogenesis, organogenesis and to the continuity of species. Cultured mouse embryonic stem cells (mESCs), a model for early embryonic cells, differ from cultured somatic cells in their capacity to remodel chromatin, in their repertoire of DNA repair enzymes, and in the regulation of cell cycle checkpoints. Using 129XC3HF1 mESCs heterozygous for Aprt, we characterized loss of Aprt heterozygosity after exposure to ionizing radiation. We report here that the frequency of loss of heterozygosity mutants in mESCs can be induced several hundred-fold by exposure to 5-10Gy of X-rays. This induction is 50-100-fold higher than the induction reported for mouse adult or embryonic fibroblasts. The primary mechanism underlying the...
A totally-enclosed, fan-cooled, rib-cooled type induction motor is adopted for an exhauster which is to be installed in a ventilation station for dust catcher in a tunnel. It has the highest capacity in Japan for the above purpose, and is provided with a cooling fan inside to recirculate cooled air, thereby improving cooling efficiency and reducing size and weight. Three-row combined angular ball bearings are used as the thrust bearings, and grease lubrication system is adopted to simplify the inspection/maintenance works. It is to be delivered to Japan Highway Public Corporation's Shizuoka Construction Bureau, Yaizu site office. Its electric specifications are 455 kW, 440 V, 890 A and 510 rpm, and its mechanical specifications are thrust load: 16 kN and impeller load: 7.2 kN. (translated by NEDO)
Abstract Herpesvirus saimiri (HVS) causes acute lymphoma and leukemia upon experimental infection of various monkey species. HVS strain C488 is also capable of transforming human T-lymphocytes to stable growth in culture. The most susceptible species for oncogenesis are New World primates, in particular the cottontop tamarin (Saguinus oedipus). However, Old World monkeys such as macaques are the most used animal model for the close-to-human situation. The limited data on HVS infection in Old World monkeys prompted us to investigate susceptibility to infection and disease induction by HVS in macaques. After having established that rhesus macaques can be infected productively, and that rhesus T-cells can be transformed in vivo by HVS, we observed induction of lymphoma in all inoculated anima...
In tomato crop, the induction of resistance emerges as an important alternative for achieving the reduction of chemicals in disease control. This study aimed to evaluate the ability of 28 Trichoderma isolates to promote the growth of tomato seedlings and to induce systemic resistance (ISR) against Xanthomonas euvesicatoria and Alternaria solani, the causal agents of bacterial spot and early blight, respectively. Twelve isolates promoted the increase of plant dry matter mass (DMM) above 100%, showing the great potential of these strains. All isolates were able to colonize the root system of tomato plants. The plant growth-promoting isolates were further evaluated for potential elicitation of ISR. Treatment of the soil with all Trichoderma isolates provided protection in tomato plants from 2...
With appropriate circuit resistance and inductance and sufficient stored energy, discharging a charged human body or component through an exploding bridgewire (EBW) detonator may cause the detonator to function or may damage the detonator. We have studied the effects of electrostatic discharge (ESD) on a number of exploding bridgewire detonators which were subjected to discharges which passed directly through the bridgewires (pin-to-pin), as well as discharges which passed from the bridge to the metal case of the detonator (pin-to-case). We have performed calculations to determine the values of inductance and resistance for which burst and melt may occur for given ESD sources, using a phenomenological model of bridgewire burst in a computer code called FIRESET. Bridge melt was computed using the same computer code, but using experimental values of bridge resistivity and specific heat up to melt. 13 refs., 5 figs.
The production method of the elastic composite containing ferrous particles and titanium barium particles dispersed in the porous silicone matrix is described in this article. Since it contains ferrous and titanium barium particles, this composite shows magnetorheological and also electrorheological properties. The electrostriction of composite samples in the electric field with maximal intensity 1.5x10{sup 6} V/m was investigated. The magnetostriction in the magnetic field with maximal induction 1 T was also investigated. It was found that samples elongate with increased electric field intensity, and the magnetic field induction was detected. By increasing the samples' elongation with increase of ferrous particles, titanium barium particles and pores number were also detected. In the investigated division of the electric and magnetic field the elongation changed in a linear way. The maximal elongation achieved was 1.59%.
We have constructed a mathematical model that describes the coherent spontaneous radiation of a macroscopically filled exciton mode. We have demonstrated qualitatively ways in which a coherent subsystem of excitons can be formed. When this occurs under the influence of an external coherent source, exciton free induction occurs, while in the case of a spontaneous transition of the excitons to a coherent state through freezing of the reservoir of intermolecular interactions superradiance occurs. We have concluded that superradiance in the system of Frenkel excitons is possible under the influence of the non-Dicke mechanisms of self-induction of correlations, when the dipole transition moments of the individual atoms are coupled into a single macroscopic effective spin through their electrostatic interaction, this being analogous to the ordering of magnetic dipole moments in a ferromagnet.
The design and operating principle of a small (50 mm in diameter and 100 mm in height) ???-73C vacuum spark gap are described. It is shown that it can be efficiently switched using a control circuit with a low (?900 V) supply voltage, which is based on an inductive energy storage and a diode opening switch that forms a high-voltage igniting pulse with a rise time of nanosecond duration. The ???-73C switching process is investigated at different rise times of igniting voltage pulses and different igniting current amplitudes. The results of tests of the spark gap operating in regimes of switching current pulses with an amplitude of 12 kA and a rise time of 800 ns are presented.
The FVM-LES-acoustic analogy method (FVM-LES-AAM), which is a hybrid prediction technique for the acoustical property computation, is presented and performed in this paper. The FVM-LES-AAM was developed by combining the finite volume method (FVM), the large eddy simulation (LES), and the Ffowcs Williams-Hawkings analogy algorithm (FWH-AA). To predict the acoustical properties of induction cookers, the FVM is used for discretizing the calculation field and building numerical equations, and the LES and FWH-AA are performed for computing the sound sources and predicting the far-field sound, respectively. Using the FVM with the unstructured grids method to discretize the control equation of Navier-Stokes was introduced for illuminating the above numerical simulation procedure. To prove the FVM...
A thermal-electric mathematical model for a squirrel cage induction motors which permits to specify the best motor for specific drive, under thermal and electric aspects based, only on manufacturer technical bulletins and technical information is presented. Changes of rotor parameters due Skin Effect and changes of winding resistances (both stator and rotor) with the temperature are considered. The accuracy of this model is appraised using experimental results. The thermal behavior and electric performance for some motors are obtained for continuos and intermittent duties with sinusoidal and non-sinusoidal voltages. (author)
For several decades, ceramic matrix composite have been attracted attention in advanced structural and tribological applications. Advanced structural ceramics are presently used in diverse tribological applications such as tips for ballpoint pens, precision instrument bearings and cutting tools inserts. Design and selection of ceramics for these applications require reliable data on the effects of temperature, load and environment on the tribological behavior of these ceramics. In the present work, #alpha#-sialon matrix composites reinforced with different amounts of #beta#-sialon fibers were produced with the aim of improving their toughness to increase the industrial applications. The wear properties of #alpha#-sialon matrix composites were evaluated by carried out wear tests using a pin-on-disk tribometer under dry conditions. The #alpha#-sialon matrix composites were manufactured by slip casting and sintered by uniaxial hot pressing. Scanning electron ...
The ultra-high pressure waterjet technology was being evaluated at Florida International University (FIU) as a baseline technology. In conjunction with FIU's evaluation of efficiency and cost, this report covers the evaluation conducted for safety and health issues. It is a commercially available technology and has been used for various projects at locations throughout the country. The ultra-high pressure waterjet technology acts as a cutting tool for the removal of surface substrates. The Husky trademark pump feeds water to a lance that directs the high pressure water at the surface to be removed. The safety and health evaluation during the testing demonstration focused on two main areas of exposure. These were dust and noise. The dust exposure was found to be minimal, which would be expected due to the wet environment inherent in the technology, but noise exposure was at a significant level. Further testing for noise is recommended because of the outdoor environment where the testing ...
We report the observation of quantum interference in superfluid 4He. The interferometer, an analog of a dc-superconducting quantum interference device (SQUID), employs a recently reported phenomenon wherein superfluid 4He exhibits Josephson frequency oscillations in an array of submicron apertures. An interference pattern is generated by reorienting the loop of the superfluid 'SQUID' with respect to the Earth's rotation vector, thereby varying the rotation flux in the loop. The experiment is performed at 2 K, a temperature 2000 times higher than previously achieved with superfluid 3He. We find that the interference exists not only when the aperture array current-phase relation is a sinusoidal function characteristic of the Josephson effect, but also at lower temperatures where it is linear and oscillations occur by phase slips. The modest requirements for the interferometer (2 K cryogenics and fabrication of apertures at the level of 100 nm) and its potential ...
In this work a comprehensive metallophysical study was carried out for two aluminosilicide slip coatings of the systems Al-Si and Al-Nb-Si and an electron-beam Co-Cr-Al-Y coating on alloy EP-539 (17...19% Cr, 4...6% Co, 2.5...4% W, 4.5...6.5% Mo, 2...3% Ti, 3...4% Al, 1.4...2% Nb, balance Ni) after high-temperature testing. The protective properties of the coatings were evaluated from the results of laboratory tests for heat resistance at 1000/sup 0/C in the combustion products of diesel fuel with added sulfur at 970, 1000, and 1060/sup 0/C for 100 h and after full-scale tests for 150, 250, 400, and 700 h. Metallographic, hardness, x-ray, and micro x-ray studies of the coating were carried out. Layer-by-layer phase composition and the lattice spacing of the main phases were determined. X-ray analysis was carried out in an a DRON-1 diffractometer in copper K/sub ..-->../-radiation, and x-ray microanalysis was carried out in a MS-46 Cameca microanalyzer
Increase usage of magnesium components in the portable electronics industries has propelled considerable research interest on the development of magnesium forging. There have been some studies done in the area of sheet metal forming and forging of axis-symmetrical parts of magnesium alloys but there are very little work done on the plane strain backward extrusion of magnesium alloy. This paper deals with the analysis of plane strain extrusion of magnesium alloy, AZ31, using numerical modeling at different extrusion conditions of temperatures and friction coefficients. A commercially available finite element package, ANSYS/LSDYNA, was used in the finite element analysis. FE simulated results, material deformation, punch force and stress/strain distributions, were compared with actual experimental data. From the numerical analysis, a decrease in forging temperature from 300 C to 250 C will lead to a moderate increase in forming resistance. The forming resistance will increase by about 2 ...
The microstructural development inside the stress induced martensite (SIM) variants in Ti-Ni-Nb alloy with various degrees of deformation have been revealed by electron microscopic observations. The orientation relationship between the SIM and the parent phase has been found: [1{bar 1}0]{sub M}{parallel}[11{bar 1}]{sub B2}, (001){sub M} 5{degree} away from (101){sub B2}. The lattice invariant shear of the SIM variants at the slightly deformed stage is dominantly (11{bar 1}) Type I twin. Besides the ordinary slip, the adjustment and development of the internal secondary twinning from (11{bar 1}) Type I twin to {l_angle}011{r_angle} Type II/ or (011) Type I twin, (001)compound twin and (111) Type I twin happen concurrently or in combination inside the SIM variants with the further deformation. The corresponding deformation mechanisms include stress induced reorientation of SIM substructural bands by the most favorably oriented twin system, stress induced migration of ...
With regard to a fracture system in the Hijiori hot dry rock artificial reservoir, an attempt was made on an interpretation which integrates different data. Major factors that characterize development and performance of an artificial reservoir are composed of a fracture system in rocks, which acts as circulating water paths, a heat exchange face and a reservoir space. The system relates not only with crack density distribution, but also with cracks activated by water pressure fracturing, cracks generating acoustic emission (AE), and cracks working as major flow paths, all of which are characterized by having respective behaviors and roles. Characteristics are shown on AE cluster distribution, crack distribution, production zone and estimated stress fields. Mutual relationship among these elements was discussed based on the Coulomb`s theory. The most important paths are characterized by distribution of slippery cracks. Directions and appearance frequencies of the slippery cracks affect ...
The Cahn-Hilliard-Navier-Stokes system is based on a well-known diffuse interface model and describes the evolution of an incompressible isothermal mixture of binary fluids. A nonlocal variant consists of the Navier-Stokes equations suitably coupled with a nonlocal Cahn-Hilliard equation. The authors, jointly with P. Colli, have already proven the existence of a global weak solution to a nonlocal Cahn-Hilliard-Navier-Stokes system subject to no-slip and no-flux boundary conditions. Uniqueness is still an open issue even in dimension two. However, in this case, the energy identity holds. This property is exploited here to define, following J.M. Ball's approach, a generalized semiflow which has a global attractor. Through a similar argument, we can also show the existence of a (connected) global attractor for the convective nonlocal Cahn-Hilliard equation with a given velocity field, even in dimension three. Finally, we demonstrate that any weak solution fulfilling ...
A press formability of magnesium alloy sheet cannot be evaluated by only general characteristics in tensile test; tensile strength, elongation n-value and r-value. For example, AZ31-alloy elongates about 20% in room temperature but breaks easily at shallow stage in deep drawing, which is caused by little local elongation (local necking). Crystallographic restriction of slip deformation in this alloy produces high strength, which almost equal to macroscopic fracture strength. In press forming, the bending under high tension requires a large deformability. A great difference in the deformability between AZ31 magnesium alloy and a strain hardened A1100 Aluminum (only 5% in elongation) is shown by static bending test with V-notch. In a rolled plate of AZ31, a crack is produced by stress concentration and propagates with reduced load at all testing temperature up to 453 K. In contrast, the point of notch in A1100 is dulled by local plastic deformation with held load in ...
The effect of mean stress, or the stress ratio (R), on the fatigue-crack growth (FCG) behavior of #alpha#-aged and #omega#-aged microstructures of the beta titanium alloy Ti-10V-2Fe-3Al was investigated. While the mean stress had a negligible effect on the FCG behavior of the #alpha#-aged microstructure, a strong effect was observed in the #omega#-aged microstructure. In particular, the values of the threshold stress-intensity range (#DELTA#K_t_h) exhibited a strong dependence on R in the #omega#-aged microstructure, while this dependence was weak in the #alpha#-aged microstructure. These effects seem to arise primarily from fracture-surface roughness-induced crack closure. The crack closure levels for the #alpha#-aged microstructure were found to be very low compared to those for the #omega#-aged microstructure. Transmission electron microscopy and scanning electron microscopy studies of microstructures and fracture surfaces were performed to gain insight into the deformation ...
The crystallography of #alpha#(hcp) precipitates formed on the #beta#(bcc) matrix grain boundaries has been studied with transmission electron microscopy (TEM) in a Ti-15V-3Cr-3Sn-3Al alloy. The #alpha# precipitates have a near-Burgers orientation relationship with respect to at least one of the adjacent #beta# grains. Among the possible 12 variants in this orientation relationship, the variant that [11 bar 20]_#alpha# is parallel to the _#beta# closest to the grain boundary plane tends to be preferred by the #alpha# precipitates. Additionally, further variant selections are made so as to minimize the deviation of orientation relationship with respect to the ''opposite'' #beta# grain from the Burgers one. Such rules in variant selection often result in the formation of precipitates with a single variant at a planar grain boundary. Prior small deformation of #beta# matrix changes the variant of #alpha# precipitates at the deformed portion of grain boundary. It is considered that the ...
Dimensional variability studies and published dimensional variability standards have been used by the foundry industry for years as an indicator of the casting process` ability to produce uniform parts. These studies are an extremely useful tool in the continuous ``dimensional dialogue`` between foundries and customers. The nature of these studies, and of the current tolerancing systems used by casting designers, leaves room for some misinterpretation and misuse of these study results. This paper contains two important discussions. The first part explains exactly what these studies represent. Following this is a brief explanation on dimensional and geometric tolerances and how they communicate dimensional requirements.
This research investigates the impact of national culture and several institutional factors on the safety performance of society and establishes statistically significant relationships between those variables. As expected, the research results reveal that some cultural variables such as uncertainty avoidance, gender orientation and institutional variables such as the degree of law avoidance can directly influence the safety performance of the society. The findings also support the inverted u-curve (Safety Kuznet curve) hypothesis indicating even if we expect a negative trend at the beginning stage of industrialization, we can expect a positive trend in safety performance as their income level continues to improve beyond a certain point.
In this talk, we explore the feasibility of quantum computation using continuous-variable systems by means of local measurements only. In the first part of the talk, we will identify crucial limitations that arise when starting from Gaussian cluster states. This is done by resorting to a Gaussian projected entangled pair picture as well as to notions of continuous-variable quantum repeater networks. In the second part, we look at instances in which these limitations can be overcome, and how suitable encodings of qubits in oscillators and feasible non-Gaussian resource states give rise to universal schemes for quantum computing.
Creep properties of modified 9 Cr-1 Mo steel, an alloy significantly improved in elevated-temperature strength over 2 1/4 Cr-1 Mo and other similar alloys, are presented here. Data are primarily on material in the normalized and tempered condition. Effects of variables such as isothermal annealing treatment, cold work, normalizing temperature, tempering temperature, notch, and biaxial stress state have also been examined. Data analysis and comparisons have shown that modified 9 Cr-1 Mo alloy is very insensitive in response to several material variables, heat treatments, and specimen design variables.
Background and ObjectivePulsed dye laser (PDL) treatment of cutaneous vascular lesions is associated with variable and unpredictable efficacy. Thus, alternative treatment...Full Text Available
The proteolytic activities of a disintegrin and metalloproteinase (ADAM); a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS), and matrix metalloproteinase (MMP) families play important...Full Text Available
The fatigue life variability of the #alpha#+#beta# titanium alloy, Ti-6Al-2Sn-4Zr-6Mo increased with decreasing stress level. The variability in life was found to be due to segregation of lives due to two failure mechanisms. A bimodal cumulative distribution model was shown to accurately describe the combined failure modes. The nominal failure processes for the two regimes were similar, with crack nucleation occurring in equiaxed #alpha#p particles, irrespective of life or stress level. However the variability in life was not controlled by the size of the crack-nucleating #alpha#p, but rather by the ability of the material to distribute deformation and avoid early crack nucleation.
the southern Arabian Gulf region left its signature on the heterogeneous aerosol .... Arabian Gulf region, since large differences in ? may be caused by ...
... Variable, Alimentos mal enlatados, especialmente verduras enlatadas en el hogar; pescado fermentado, papas asadas en papel de aluminio, ajo envasado. ...
Brains are usually described as input/output systems: they transform sensory input into motor output. However, the motor output of brains (behavior) is notoriously variable, even under identical sensory...Full Text Available
A central composite design was employed to optimize the extraction of pectin with citric acid. The independent variables were citric acid concentration (0.086-2.91% w/v) and extraction time (17-102min). The combined effect of these variables on the degree of esterification was investigated. Results have shown that the generated regression models adequately explained the data variation and significantly represented the actual relationship between the independent variables and the responses. Besides that, the citric acid concentration was the most important factor to affect the degree of esterification, as it exerted a significant influence on the dependent variable. Lower citric acid concentration increased the pectin degree of esterification. The surface response showed the relationships b...
In this paper we present a complete solution to the problem of multifractal analysis of multiple ergodic averages in the case of symbolic dynamics for functions of two variables depending on the first coordinate.
Worldwide century-long forest hydrologic research has documented that deforestation and forestation (i.e. reforestation and afforestation) can have variable ...
Jul 25, 2011 ... Koji Mukai's Bibliography. Invited Reviews. Mukai, K. 1994, "ASCA PV Phase Observations of Cataclysmic Variables," in "New Horizon of X-ray ...
According to classical concepts of physiologic control, healthy systems are self-regulated to reduce variability and maintain physiologic constancy. Contrary to the predictions of homeostasis, however,...Full Text Available
Background and AimsAnnonaceae are one of the largest families of Magnoliales. This study investigates the comparative floral development of 15 species to understand the basis for...Full Text Available
Statistically based experimental designs were applied to screen and optimize the bioleaching of spent hydrocracking catalyst by Penicillium simplicissimum. Eleven factors were examined for their significance on bioleaching using a Plackett-Burman factorial design. Four significant variables (pulp density, sucrose, NaNO"3, and yeast extract concentrations) were selected for the optimization studies. The combined effect of these variables on metal bioleaching was studied using a central composite design (CCD). Second-order polynomials were established to identify the relationship between the recovery percent of the metals and the four significant variables. The optimal values of the variables for maximum metals bioleaching were as follows: pulp density (4.0%, w/v), sucrose (90g/L), NaNO"3 (2...
Knowledge on environmental variability and how it is affected by disturbances is crucial for understanding patterns of biodiversity and determining adequate conservation strategies. The aim of this study is to assess environmental variability in patches undergoing post-fire vegetation recovery, identifying trends of change and their relevant drivers. We particularly evaluate: the value of three spectral indices derived from Landsat satellite data [Normalized Burn Ratio (NBR), Normalized Difference Vegetation Index (NDVI) and Wetness Component of the Tasseled Cap Transformation (TCW)] for describing secondary succession; the effectiveness of three metrics (diversity, evenness and richness) as indicators of patch variability; and how thematic resolution can affect the perception of environme...
Wildlife Refuge, CA Rare and endangered endemic plants Diana Anderson Northern Arizona University Geomorphology Kathryn Thomas USGS, Flagstaff, AZ Vegetation dynamics John...
Climate variability greatly affects animals through direct and indirect effects. Animals with slow reproductive adaptation to ecological changes such as large mammals are likely to have evolved mechanisms to anticipate early such impacts of climate variability on the environment. One of the adaptive mechanisms between reproductive costs and benefits in mammals affects parental investment through biases in sex ratio. Deer might be likely to show an early detection of climate variability because conception takes place in early autumn, but the main raising cost in deer concerns lactation, which takes place at the end of the following spring. The aim of this paper is to assess whether there is a relationship between global indices of climate variability such as El Ni?o-Southern Oscillation (EN...
The study of genetic variability within natural populations of pathogens may provide insight into their evolution and pathogenesis. We used a Mycobacterium tuberculosis high-density...Full Text Available
The study has analysed the effects of various factors on hydroelectric power generation potential to include climate change/variability, water demand, and installation of proposed hydroelectric power schemes in the Zambezi River Basin. An assessment of historical (1970?2000) power potential in relation to climate change/variability at existing hydro electric power schemes(Cahora Bassa, Kariba, Kafue Gorge and Itezhi-Tezhi) in the Zambezi River Basin was conducted. The correlation of hydroelectric power potential with climate change/variability aimed at observing the link and extent of influence of the latter on the former was investigated. In order to predict the future outlook of hydro electric power potential, General Circulation Models (GCM) were used to generate projected precipitation...
measure meteorological variables and bulk water temper- ature. The locations of the buoys are given in Table 1. TB2 and TB3 were moved slightly farther south ...
We construct the Baxter Q-operator and the representation of the Separated Variables (SoV) for the homogeneous open SL(2,R) spin chain. Applying the diagrammatical approach, we calculate Sklyanin's integration measure in the separated variables and obtain the solution to the spectral problem for the model in terms of the eigenvalues of the Q-operator. We show that the transition kernel to the SoV representation is factorized into the product of certain operators each depending on a single separated variable. As a consequence, it has a universal pyramid-like form that has been already observed for various quantum integrable models such as periodic Toda chain, closed SL(2,R) and SL(2,C) spin chains.
We obtain an elegant and useful description of the dynamics of Szekeres dust models (in their full generality) by means of "quasi--local" scalar variables constructed by suitable integral distributions that can be interpreted as weighed proper volume averages of the local covariant scalars. In terms of these variables, the field equations and basic physical and geometric quantities are formally identical to their corresponding expressions in the spherically symmetric LTB dust models. Since we can map every Szekeres model to a unique LTB model, rigorous results valid for the latter models can be readily generalized to a non--spherical Szekeres geometry. The new variables lead naturally to an initial value formulation in which all scalars are expressed as scaling laws in terms of their values at an arbitrary initial space slice. These variables also yield a significant simplification of numerical work, ...
An overview of the developments and designs of electric cars is given. It can be concluded that the numbers of electric-powered vehicles in the world, presented by different companies, are confusing and that it is very difficult to categorize the electric cars because of the many different prototypes under development sofar. Also an introduction is given on the engine technology of such cars. Attention is paid to the direct current (DC) motor, the induction motor, the brushless DC-motor, and the synchronous motor. 2 figs., 4 ills., 35 refs.
This report describes the test of a dynamic phase compensation unit for a wind turbine with directly connected induction generators. The compensation unit is based on thyristor switched capacitors, where conventional wind turbine compensations use mechanical contactors to switch the capacitors. The influence on power quality analysed, and influence on component lifetime is discussed. Besides, simulation models in Matlab/Simulink are presented, including a flicker meter model. (au)
The motion of an accelerated charge in a vacuum is analyzed, via the superposition principle and Fourier analysis, into uniform-motion components, which include bradyonic as well as tachyonic contributions. It is shown that the former contribute only to the induction fields whereas the latter are the source of the radiation emitted by the charge, via the Sommerfeld-Cerenkov mechanism. This result calls for a reexamination of some recently formulated theories of superluminal particles.
Purpose.To report the increased production of extracellular transforming growth factor β-induced protein (TGFBIp) by human corneal epithelial cells (HCECs) after induction...Full Text Available
We review the status of free electron laser (FEL) research being conducted at LBL and LLNL as part of a broader program of research on two beam accelerators (TBAs). Induction accelerator-driven FELs for use as power sources for high-gradient accelerators are discussed, along with preliminary cost estimates for this type of power source. Finally, a promising new version of an FEL/TBA is described. 25 refs., 1 fig., 3 tabs.
Pacini (1973) has considered basic theoretical expectations regarding the magnetic dipole radiation and unipolar induction of pulsars, taking into account observational results. The present investigation is concerned with the difference between the two braking mechanisms. Attention is also given to a statistical study involving a comparison of the two braking mechanisms with observations. The study makes use of the observational data for the distribution of apparent beamwidth, and a geometrical method. The obtained results agree with the theory of magnetic dipole radiation.
1. The induction of long-term potentiation (LTP) was investigated in the rat dentate gyrus in the presence of ryanodine, an agent which is known to selectively bind to the ryanodine receptor (RyR) Ca2+...Full Text Available
A cDNA library was constructed from HL60 human promyelocyte poly(A)+ RNA harvested 3 h after induction of macrophage differentiation with 12-O-tetradecanoyl phorbol-13-acetate in the presence of cycloheximide....Full Text Available
From the frequency of diagnostic radiologic examinations and their radiation dose delivered to the population the risk of cancer induction and genetic damage is calculated on the basis of the risk factors given by the ICRP. Thus 0.38 % and 3 % of the total mortality for cancer and leukemia, resp., can be attributed to X-ray diagnostics. Chest examinations alone result in 0.07-0.7 damages per 100,000 persons depending on the imaging technique applied. (author).
This research has two main goals; (1) to quantify mechanisms for radon entry into homes of different types and to determine the fraction of indoor radon attributable to each source and (2) to model and calculate the dose (and therefore alpha particle fluence) to cells in the human and animal tracheobronchial tree that is pertinent to induction of bronchogenic carcinoma from inhaled radon daughters.
This report continues the studies of simplified methods, of magnetic diagnostics in application to TCA/BR tokamak. Here we study the accuracy of known formula for {beta}{sub 1} + l{sub 1}/2 determination from the poloidal magnetic field asymmetry. Errors of the diamagnetic measurements due to vibrations of the vacuum vessel are also considered. (author). 3 refs., 1 fig., 1 tab.
Primary leaves of 7- to 9-day-old etiolated seedlings of Phaseolus vulgaris L. var. Red Kidney infiltrated in darkness with aqueous solutions of α, α′-dipyridyl,...Full Text Available
BackgroundAfrican horse sickness virus (AHSV) causes a non-contagious, infectious disease in equids, with mortality rates that can exceed 90% in susceptible horse populations....Full Text Available
The use of irrigation systems in the proximity of high voltage transmission lines is increasing. This study examines the induced voltages and currents on a pivotal irrigation system operating under a 765 kV line. With a few simple precautions such as a system can be operated in complete safety. 1 ref.
PNAS-4, a novel pro-apoptotic gene activated during the early response to DNA damage, can inhibit proliferation via apoptosis when overexpressed in some tumor cells. Recent studies have indicated that honokiol can induce apoptosis, inhibit angiogenesis, and suppress tumor growth. In the present study, we investigated whether mouse PNAS-4 (mPNAS-4) could augment the apoptosis of tumor cells induced by honokiol in vitro, and whether the antiangiogenic activity of honokiol and induction of apoptosis by mPNAS-4 could work cooperatively to improve the antitumor efficacy in vivo. In vitro, mPNAS-4 inhibited proliferation of murine colorectal carcinoma CT26 and Lewis lung carcinoma LL2 cells through induction of apoptosis, and significantly augmented the apoptosis of CT26 and LL2 cells induced by honokiol. Compared with treatment with mPNAS-4 or honokiol alone, in vivo systemic administration of an expression plasmid encoding mPNAS-4 and low-dose ...
Dendritic cells (DC) are the most potent antigen-presenting cells and play a central role in the induction of antiviral immune responses. Recently, we have shown that monocyte-derived DC (MoDC) from...Full Text Available
The study examined the possibility for fuel ignition by spark discharge caused by induction effects under high voltage transmission lines. Theoretical background information on capacitive spark discharges and fuel ignition processes is given. Laboratory experiments were conducted to test the dependence of fuel ignition on three parameters: impedance in discharge path, multiple discharges, and larger electrode shapes. The results of these tests are discussed in terms of fuel ignition possibilities under high voltage transmission lines.
Occupational and environmental exposure to organic ligands, solvents, fuel hydrocarbons, and polychlorinated biphenyls are linked with increased risk of hematologic malignancies. DOE facilities and waste sites in the U.S. are contaminated with mixtures of potentially hazardous chemicals such as metals, organic ligands, solvents, fuel hydrocarbons, polychlorinated biphenyls and radioactive isotopes. A major goal of this project was to establish linkage between chemical/radiation exposure and induction of genomic damage in target populations with the capability to undergo transformation.
The objective of this study was to determine if genistein (GEN) modulation of the immune responses might contribute to the increased host resistances to tumors. A time-course study was performed...Full Text Available
Two cellular DNA regions representing common domains for proviral DNA integration ( Mlvi -1 and Mlvi -2) have been identified in Moloney murine leukemia virus-induced rat thymic lymphomas. Cellular...Full Text Available
This paper proposes a novel control strategy for tracking peak power in a wind or wave energy system using a squirrel cage induction generator. It eliminates wind speed measurement or estimation and uses a simple scalar technique by exploiting the cubic nature of the power curve. The method works even when air velocity is varying dynamically. (author)
Because of questions regarding current density and inductance estimates of the Atlas oil transmission line in the region where the vertical plates connect to the disk line, calculations using the 3D FE program Flux3d were initiated. Flux3d inductance values are nearly that estimated by D. Scudder. Calculations for three base designs of E. Ballard and D. Pierce were completed where several variations for each base design were used to determine the important parameters affecting inductance and to check inductance consistency. Flux3d showed for the first base design a very high current density of 36MA/m at the connection between the vertical and horizontal ground plates resulting in a magnetic pressure of 120 kpsi. The second base design modified this connection to reduce the current density to 20MA/m and 36 kpsi and for design 3 current density is 17MA/m. Maximum current density on the hot plates is ...
Synthesis of silver nanoparticles based on a polyol process and variable frequency microwave (VFM) was investigated. Comparing to a thermal method, the reaction by VFM radiation was much faster. The effects of silver nitrate concentration, poly(N-vinylpyrrolidone) (PVP) concentration, reaction time and reaction temperature were studied. It was found that the higher concentration of silver nitrate, longer reaction time and higher temperature increased the particle size while the higher concentration of PVP decreased the particle size.
A physical model of free-electron laser (FEL) amplifier with variable-parameter wiggler magnets for one-dimensional numerical simulation is presented and a numerical example is given. The wiggler parameters, efficiency of energy conversion between electron beam and laser field, laser intensity, phase-space distributions and energy spectrum of electrons are computed. The period of synchronous oscillation and saturation value of laser intensity agree with estimated one.
In the case of large capacity steam turbines the conventional nozzle group control is, for mechanical and thermodynamic reasons, diminishing more and more in importance in favour of variable pressure control. A design for constant-pressure operation as an alternative to nozzle group control is described; this demonstrates a series of important advantages compared with the latter. (orig.).
This book contains the Proceedings of the Conference on Climate and Water under the following groupings: Impacts of climatic variability and change-resulting from the changes in hydrological variables; Aquatic environment; Terrestrial environment; Coastal zones and navigation; Urban and industrial water supply and drainage; Energy production; Intropogenic changes of climate and water management problems; Flood potential; Irrigation and land drainage.
This book contains the Proceedings of the Conference on Climate and Water under the following groupings: Impacts of climatic variability and change-resulting from the changes in hydrological variables; Aquatic environment; Terrestrial environment; Coastal zones and navigation; Urban and industrial water supply and drainage; Energy production; Intropogenic changes of climate and water management problems; Flood potential; Irrigation and land drainage.
Two major developments have given impetus to wider adoption of variable-speed turbine/generators in hydroelectric plants, both essentially environmental: (1) the need for stream-bed stability below river dams, and (2) the need to minimize fish damage. Also, the need to stabilize pumped-storage and generating efficiencies to match extreme changes in head levels has been a driving force. Variable-speed operation in hydro applications is relatively new to North America. In other parts of the world, it has been used in pumped-storage plants since 1971. In the US, and increasing potential exists for variable-speed hydro, considering the 30 pumped-storage plants already in operation and several river plants struggling with high head fluctuations--including four at stations operated by the Bonneville Power Administration. Several modifications to hydro-plant hardware and operating procedures are actively being considered at ...
The effect of fetal distress on the neonatal brain was investigated by neonatal CT brain scan, FHR monitoring and mode of delivery. This study involved 11 cases of full term vertex delivery in which FHR was recorded by fetal direct ECG during the second stage labor. All infants weighed 2,500 g or more. FHR monitoring was evaluated by Hon's classification. Neonatal brain edema was evaluated by cranial CT histgraphic analysis (Nakada's method). 1) Subdural hemorrhage was noted in 6 of 7 infants delivered by vacuum extraction or fundal pressure (Kristeller's method). 2) Intracranial hemorrhage was demonstrated in all of 3 infants with 5-min. Apgar score 7 or less. 3) Two cases with prolonged bradycardia and no variability had intraventricular or intracerebral hemorrhage which resulted in severe central nervous system damage. 4) The degree of neonatal brain edema correlated with 5-min. Apgar score. 5) One case with prolonged bradycardia and ...
The effect of fetal distress on the neonatal brain was investigated by neonatal CT brain scan, FHR monitoring and mode of delivery. This study involved 11 cases of full term vertex delivery in which FHR was recorded by fetal direct ECG during the second stage labor. All infants weighed 2,500 g or more. FHR monitoring was evaluated by Hon's classification. Neonatal brain edema was evaluated by cranial CT histgraphic analysis (Nakada's method). 1) Subdural hemorrhage was noted in 6 of 7 infants delivered by vacuum extraction or fundal pressure (Kristeller's method). 2) Intracranial hemorrhage was demonstrated in all of 3 infants with 5-min. Apgar score 7 or less. 3) Two cases with prolonged bradycardia and no variability had intraventricular or intracerebral hemorrhage which resulted in severe central nervous system damage. 4) The degree of neonatal brain edema correlated with 5-min. Apgar score. 5) One case with prolonged bradycardia and no ...
Lateral and vertical variabilities in the bulk and mechanical properties of silicic volcanic tuff at the potential nuclear waste repository site in Yucca Mountain, NV have been evaluated. Laboratory measurements have been performed on tuff specimens recovered from boreholes located to support the design of the Exploratory Studies Facility/North Ramp. The data include dry and saturated bulk densities, average grain density, porosity, compressional and shear wave velocities, elastic moduli, and compressional and tensional fracture strengths. Data from eight boreholes aligned in a northwest-southeast direction have been collected under the required quality assurance program. Three boreholes have penetrated the potential repository horizon. The information collected provides for an accurate appraisal of the variability of rock properties in the vicinity of the boreholes. As expected, there is substantial variability in the bulk ...
To assess the variability and systematic differences in polyp measurements on optical colonoscopy and CT colonography. Gastroenterologists measured 51 polyps by visual estimation, forceps comparison and linear probe. CT colonography observers randomly assessed polyp size two-dimensionally (abdominal and intermediate window) and three-dimensionally (manually and semi-automatically). Linear mixed models were used to assess the variability and systematic differences between CT colonography and optical colonoscopy techniques. The variability of forceps and linear probe measurements was comparable and both showed less variability than measurement by visual assessment. Measurements by linear probe were 0.7 mm smaller than measurements by visual assessment or by forceps. The variability of all CT colonography techniques was lower than for measurements by forceps or visual assessment and ...
In this article, we studied the effects of variable viscosity and thermal conductivity on an unsteady two-dimensional laminar flow of a viscous incompressible conducting fluid past a semi-infinite vertical porous moving plate taking into account the effect of a magnetic field in the presence of variable suction. The fluid viscosity is assumed to vary as an inverse linear function of temperature but the thermal conductivity is assumed to vary as a linear function of temperature. It is assumed that the porous plate moves with a constant velocity in the direction of fluid flow, and the free stream velocity follows the exponentially increasing small perturbation law. The governing equations for the flow are transformed into a system of nonlinear ordinary differential equations by perturbation ...
Diet overlap and niche breadth are well-known species traits from trophic ecology that can assist in explaining how species interact and coexist as well as the ecological mechanisms that influence biodiversity. In the present study, we analyzed the relationships between these trophic variables and indicators of resource availability with some attributes of fish assemblages (species richness, Shannon diversity index, evenness, density and individual body size). The physical and chemical characteristics of the biotopes (topography, water quality and conservation of slopes) were examined to identify possible patterns. Monthly sampling using electrofishing was conducted in 2003 along five streams located in the Cuiab? River watershed. The relationships between environmental variables and attri...
An automotive powertrain includes a conventional piston engine, a continuously variable ratio transmission, an engine speed sensor and a feedback control system. The control system adjusts both the transmission ratio and the throttle valve in the engine carburetor or fuel metering system in response to the position of the accelerator pedal and in response to the crankshaft speed as measured by the engine sensor. The transmission provides extreme overdrive gear ratios which allow the engine to be operated at wide open throttle even during moderate cruising, and, in addition, the engine carburetor or fuel metering system is calibrated to deliver to the engine a stoichiometric air-fuel mixture which is combined, before combustion, with a special proportion of recirculated exhaust gas. As a result of extensive wide open throttle engine operation with the above mentioned intake charge composition, combustion variables are optimized to produce ...
Abstract In this paper, a new predictive model that can forecast the performance of a vertical axis wind turbine (VAWT) is presented. The new model includes four primary variables (rotor velocity, wind velocity, air density, and turbine power output) as well as five geometrical variables (rotor radius, turbine height, turbine width, stator spacing, and stator angle). These variables are reduced to include the power coefficient (Cp) and tip speed ratio (TSR). A power coefficient correlation for a novel VAWT (called a Zephyr Vertical axis Wind Turbine (ZVWT)) is developed. The turbine is an adaptation of the Savonius design. The new correlation can predict the turbine's performance for altered stator geometry and varying operating conditions. Numerical simulations with a rotating reference f...
This paper analyses Italian interregional migration flows. The approach taken is to decompose labour mobility flows into short distance and long distance migration and to model the effects of economic variables, social capital and quality of life variables, and amenity variables, on the mobility behaviour of individuals. We estimate these different types of migration flows using a negative binomial model, augmented with instruments to control for potential endogeneity issues. Our findings demonstrate that long distance migration reflects a disequilibrium model of migration whereas short distance migration largely reflects an equilibrium model of migration. As such, attempts to model interregional migration in general will be mis-specified as the simultaneously-operating underlying mobility...
The unavoidable irreversible losses of power in a heat engine are found to be of quantum origin. Following thermodynamic tradition a model quantum heat engine operating by the Otto cycle is analyzed. The working medium of the model is composed of an ensemble of harmonic oscillators. A link is established between the quantum observables and thermodynamical variables based on the concept of canonical invariance. These quantum variables are sufficient to determine the state of the system and with it all thermodynamical variables. Conditions for optimal work, power and entropy production show that maximum power is a compromise between the quasistatic limit of adiabatic following on the compression and expansion branches and a sudden limit of very short time allocation to these branches. At high temperatures and quasistatic operating conditions the efficiency at maximum power coincides with the endoreversible result. The optimal ...
Various SST indices in the Indo-Pacific region have been proposed in the literature in light of a long-range seasonal forecasting of the Indian Summer Monsoon (ISM). However, the dynamics associated with these different indices have never been compared in detail. To this end, the present work re-examines the variabilities of ISM rainfall, onset and withdrawal dates at interannual timescales and explores their relationships with El Ni?o-Southern Oscillation (ENSO) and various modes of coupled variability in the Indian Ocean. Based on recent findings in the literature, five SST indices are considered here: Ni?o3.4 SST index in December?January both preceding [Nino(?1)] and following the ISM [Nino(0)], South East Indian Ocean (SEIO) SST in February?March, the Indian Ocean Basin (IOB) mode in ...
The primary objective of batch data as trajectory alignment (or synchronization) is to standardize the data sampling per batch according to the evolution of the process, and secondarily to homogenize the samples per run. The use of an indicator variable performs both objectives well. Two examples from the pharmaceutical sector are discussed to illustrate the different ways to deal with uneven samples across batches and across variables in the same batch. Since trajectory alignment requires large time investment, a simple triage approach is proposed to assess the need to analyze the dynamics of a given process and hence perform alignment. The presented examples are representative of a broad variety of batch processes that are operated by recipe in the pharmaceutical sector. In our experienc...
Abstract Mammalian teeth exhibit incremental structures representing successive forming fronts of enamel at varying time scales, including a short daily increment called a cross striation and a long period called a stria of Retzius, the latter of which, in humans, occurs on average every 8-9 days. The number of daily increments between striae is called the repeat interval, which is the same period as that required to form one increment of bone, i.e. the lamella, the fundamental - if not archetypal - unit of bone. Lamellae of known formation time nevertheless vary in width, and thus their measures provide time-calibrated growth rate variability. We measured growth rate variability for as many as 6 years of continuously forming primary incremental lamellar bone from midshaft femur histologic...
An interesting line of research is the investigation of the laws of random variables known as Dirichlet means. However, there is not much information on interrelationships between different Dirichlet means. Here, we introduce two distributional operations, one of which consists of multiplying a mean functional by an independent beta random variable, the other being an operation involving an exponential change of measure. These operations identify relationships between different means and their densities. This allows one to use the often considerable analytic work on obtaining results for one Dirichlet mean to obtain results for an entire family of otherwise seemingly unrelated Dirichlet means. Additionally, it allows one to obtain explicit densities for the related class of random variables that have generalized gamma convolution distributions and the finite-dimensional distribution of their associated L\\'{e}vy processes. ...
Purpose Nonpoint sources (NPS) pollution has been an important cause for water quality impairment worldwide. To take the temporal variations of both NPS pollution and in-stream attenuation into consideration, an inverse modeling approach and the load duration curve (LDC) method were combined for variable nutrient total maximum daily load (TMDL) development. Methods Water quality and hydrological parameters were monitored monthly along the ChangLe River system in 2004?2008. The catchment NPS export load (EL) and TMDL for total nitrogen (TN) were estimated by the inverse format of an existing stream nutrient transport equation. The LDC method was used to describe the variability of EL, TMDL, requiring load (RLR) and percent (the ratio between the RLR and the EL, RPR) reduction, and then to s...
The central engine of Gamma Ray Bursts is hidden from direct probing with photons mainly due to the high densities involved. Inferences on their properties are thus made from their cosmological setting, energetics, low-energy counterparts and variability. If GRBs are powered by hypercritical accretion onto compact objects, on small spatial scales the flow will exhibit fluctuations, which could in principle be reflected in the power output of the central engine and ultimately in the high energy prompt emission. Here we address this issue by characterizing the variability in neutrino cooled accretion flows through local shearing box simulations with magnetic fields, and then convolving them on a global scale with large scale dynamical simulations of accretion disks. The resulting signature is characteristic, and sensitive to the details of the cooling mechanism, providing in principle a discriminant for GRB central engine properties.
Multi-millennial climate changes were relatively minor over the mid-late Holocene in the British Isles, because orbitally forced insolation changes were smaller than those at higher latitudes. Centennial climate variability is thus likely to have exerted a greater influence on the environment and human society of the region. Proxy-climate records from the British Isles covering the last 4500years are assembled and re-evaluated with the aim of identifying centennial climate variability reflected by multi-proxy indicators. The proxies include bog oak populations, peatland surface wetness, flooding episodes from fluvial deposits, speleothem annual band width and oxygen isotopes, chironomids from lake sediments and sand and dune deposition. Most proxies reflect water balance rather than temper...
This paper presents a study on Manasbal lake, which is one of the high altitude lakes in the Kashmir Valley, India. Eighteen water samples were analysed for major ions and trace elements to assess the variability of water quality of the lake for various purposes. Geostatistics, the theory of regionalized variables, was then used to enhance the dataset and estimate some missing spatial values. Results indicated that the concentration of major ions in the water samples in winter was higher than in summer. The scatter diagrams suggested the dominance of alkaline earths over the alkali elements. Three types of water were identified in the lake that are referred to as Ca?HCO3, Mg?HCO3 and hybrid types. The lake water was found to be controlled by rock?water interaction with carbonate lithology ...
This paper focuses on a factorial-based design strategy. The approach provides an efficient and statistically reliable means for assessing the influence of multivariable effects. It is applied to the detection and evaluation of damage in impacted composite sandwich panels. The experimental results obtained from this test strategy are utilized to form an empirical response function. The resulting polynomial relates damage area to residual compression strength at values of independent variables for which testing did not occur. The response function also identifies nonlinear interaction effects of key variabes that cannot be easily ascertained by traditional single-variable test strategies. Independent variables evaluated include core thickness, number of face sheet plys and impact energy. The methodology presented allows the designer to predict with more confidence the damage tolerance of a composite material component, and ...
A variable gene delivery system has been developed based on conjugating chitosan to biotin through a functionalized poly(ethylene glycol) (PEG) spacer, which can be used to further bind different molecules on the outer layer of a polymer/DNA complex by streptavidin (SA)-biotin linkage. In this study, TAT-conjugated SA was used as the model molecule to prove the conjugation function of the prepared complex. In addition, low-molecular-weight poly(ethyleneimine) (PEI) was added into the polymer/DNA complex to increase the transfection efficiency. The results of the luciferase assay show that the transfection efficiency of the prepared complex was significantly correlated with the amount of PEI and was further enhanced when TAT was conjugated to the complex by SA-biotin linkage. Considered to have negligible cytotoxic effects, the variable gene delivery complex prepared in this study would be of considerable potential as carriers for in vitro ...
Experiments based on a 23 central composite full factorial design were carried out in 200-ml stainless-steel containers to study the pretreatment, with dilute sulfuric acid, of a sugarcane bagasse sample obtained from a local sugar?alcohol mill. The independent variables selected for study were temperature, varied from 112.5?C to 157.5?C, residence time, varied from 5.0 to 35.0 min, and sulfuric acid concentration, varied from 0.0% to 3.0% (w/v). Bagasse loading of 15% (w/w) was used in all experiments. Statistical analysis of the experimental results showed that all three independent variables significantly influenced the response variables, namely the bagasse solubilization, efficiency of xylose recovery in the hemicellulosic hydrolysate, efficiency of cellulose enzymatic saccharificatio...
The possibility of the group preconcentration of Zr(4), Hf(4), Nb(5), and Ta(5) countercurrent liquid chromatography using extraction systems based on di-2-ethylhexylphosphoric acid N-benzoyl-N-phenylhydroxylamine, and tetraoctylethylenediamine (TOEDA) is studied. A method have been proposed for the group extraction of Zr(4), Hf(4), Nb(5), and Ta(5) from solution of geological samples. At the stage of the preconcentration of Zr(40, Hf(4), Nb(5) and Ta(5) with a 0.1 M solution of TOEDA in chloroform from mixture of oxalic (0.01 M) and hydrochloric (0.1 M) acids, matrix components are eluted with a flow of the mobile phase, Then, upon changing the eluent (2.0 M HCl), the four elements mentioned above are extracted to a small (7-8 mL) eluate fraction. The results of determining Zr, Hf, Nb, and Ta by inductively coupled plasma atomic emission spectrometry in the international standard reference material Granite GM after their preconcentration in the system with TOEDA ...
The crystallization of calcium sulfate from aqueous solutions with NaCl is both geological and industrial interest because NaCl is the dominant solute in natural brines and many industrial fluids. Induction periods for the nucleation of calcium sulfate dihydrate were experimentally determined as a function of supersaturation in NaCl solutions from 0 to 6 m at 25 C and in 3.0-m NaCl solutions at temperatures from 25 to 90 C. Using classic nucleation theory, the interfacial tension between gypsum and 3.0-m NaCl solution was estimated to be about 39 mJ/m[sup 2] at 25 C and increases with increasing temperature (to 63 mJ/m[sup 2] at 90 C). It was observed that the induction period decreases with increasing NaCl concentrations up to 3 m and then starts to increase slightly at a given temperature and saturation state. The electrolyte effect on nucleation was proportional to the enhanced solubility of calcium sulfate dihydrate in NaCl solutions. This ...
Nitrogen ion implantation improves the wear resistance of Ti-6Al-4V alloys by forming a hard TiN superficial passivation layer. However, the thickness of the layer formed by traditional ion implantation is typically 100-200 nm and may not be adequate for many industrial applications. We propose to use radio-frequency (RF) plasma nitriding and nitrogen plasma immersion ion implantation (PIII) to increase the layer thickness. By using a newly designed inductively coupled RF plasma source and applying a series of negative high voltage pulses to the Ti-6Al-4V samples. RF plasma nitriding and nitrogen PIII can be achieved. Our process yields a substantially thicker modified layer exhibiting more superior wear resistance characteristics, as demonstrated by data from micro-hardness testing, pin-on-disc wear testing, scanning electron microscopy (SEM), as well as Auger electron spectroscopy (AES). The performance of our newly developed inductively ...
Nitrogen ion implantation improves the wear resistance of Ti-6Al-4V alloys by forming a hard TiN superficial passivation layer. However, the thickness of the layer formed by traditional ion implantation is typically 100-200 nm and may not be adequate for many industrial applications. We propose to use radio-frequency (RF) plasma nitriding and nitrogen plasma immersion ion implantation (PIII) to increase the layer thickness. By using a newly designed inductively coupled RF plasma source and applying a series of negative high voltage pulses to the Ti-6Al-4V samples. RF plasma nitriding and nitrogen PIII can be achieved. Our process yields a substantially thicker modified layer exhibiting more superior wear resistance characteristics, as demonstrated by data from micro-hardness testing, pin-on-disc wear testing, scanning electron microscopy (SEM), as well as Auger electron spectroscopy (AES). The performance of our newly developed inductively ...
Samples of air-dust-concentration- and air-dust-deposit measurements were digested by a standardized wet digestion procedure and the amounts of substances in the dust according to class I TA Luft by Atomic Emission Spectroscopy with Inductively Coupled Plasma (AES-ICP). The characteristic values for procedures according to VDI 2449, sheet 1, were determined for lead, vanadium, cadmium, chromium, copper, nickel and zinc. By partial automatic control of the digestion procedure the personel expenditure of work could be reduced by a factor 13. Dust filter samples were analysed without sample preparation by evaporating the material with a solid state laser. The absolute detection limit was between 1 and 100 ng/cm"2 for the elements arsenic, cadmium, cobalt, chromium, mercury, antimony, selen and thallium. For sampling by means of the Beta-Staubmeter the relative detection limits for the laser-ICP were 10-fold lower than by use of a nebulizer. (orig.).
Homogeneous mixtures of Ce0.8Gd0.2O1.9 (GDC) and La0.6Sr0.4Co0.2Fe0.8O3 (LSCF) nanopowders were successfully synthesized using induction plasma by axial injection of a solution. The resulting nanocomposite powders consisted of two kinds of nanopowders with different mass ratio of GDC/LSCF, such as 3/7 and 6/4. The morphological features, crystallinity, and the phases of the synthesized powders were characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), local energy-dispersive x-ray spectroscopy (EDS) analysis, and x-ray diffraction (XRD). The nanopowders are almost globular in shape with a diameter smaller than 100?nm and their BET specific areas are around 20?m2?g?1. The GDC and LSCF phases are well distributed in the nanopowders. In addition, suspens...
Dose measurements were performed in several body regions of patients suffering from inflammatory degenerative diseases (humeral epicondylitis, humeroscapular periarthritis, gonarthrosis, axillary hidradenitis, rheumatoid arthritis, coxarthrosis, parotitis). The problem of the radiation induction of neoplasms is predominant concerning somatic as well as genetic risk, discussed by example of the most frequently occurring organ cancer. Compared to the rate of breast cancer in the highly developed industrial states (5,000 to 6,000 cancers/100,000 women) the 'radiation induction' calculated according to a mathematical model of ICRP 26 (1.25 cases of death for breast cancers/100,000 women following for example irradiation of epicondylitis) is behind several powers of ten and not demonstrable. The genetic radiation exposure is also low. Derived from the measurements it is wrong to give up reliable and approved indications of radiotherapy of ...
Recently there has been much concern with the ability of plants to uptake heavy metals from their surroundings. With the development of instrumental techniques with low detection limits such as inductively coupled plasma-mass spectrometry (ICP-MS), attention is shifting toward achieving faster and more elegant ways of oxidizing the organic material inherent in environmental samples. Closed-vessel microwave dissolution was compared with conventional methods for the determination of concentrations of cerium, samarium, europium, terbium, uranium and thorium in a series of samples from the National Institute of Standards and Technology and from fields in Idaho. The ICP-MS technique exhibited detection limits in parts-per-trillion and linear calibration plots over three orders of magnitude for the elements under study. The results obtained by using nitric acid and hydrogen peroxide in a microwave digestion system for the analysis of reference materials showed close ...
Rhodopseudomonas viridis was grown in liquid culture at 30 degrees C anaerobically in light (generation time, 13 h) and under microaerophilic growth conditions in the dark (generation time, 24 h). The bacterium could be cloned at the same temperature anaerobically in light (1 week) and aerobically in the dark (3 to 4 weeks) if oxygen was limited to 0.1%. Oxygen could not be replaced by dimethyl sulfoxide, potassium nitrate, or sodium nitrite as a terminal electron acceptor. No growth was observed anaerobically in darkness or in the light when air was present. A variety of additional carbon sources were used to supplement the standard succinate medium, but enhanced stationary-phase cell density was observed only with glucose. Conditions for induction of the photosynthetic reaction center upon the change from microaerophilic to phototrophic growth conditions were investigated and optimized for a mutant functionally defective in phototrophic growth. R. viridis ...
Chromium electroplated AISI 316L stainless steel was nitrided using inductively coupled plasma (ICP) for application in the bipolar plate of a polymer electrolyte membrane fuel cell (PEMFC). A continuous and thin chromium nitride layer was formed at the surface of the samples after ICP nitriding for 2 h at 400 C. The interfacial contact resistance (ICR) and corrosion resistance in simulated PEMFC operating conditions were higher than the required values, while they varied with the applied dc bias voltage during the nitriding process. The ICR value decreased with an increase in bias voltage. Potentiodynamic polarization measurements showed that all of the nitrided samples had excellent corrosion resistance with a current density of {proportional_to}10{sup -7} A cm{sup -2} at the cathode. It was also found that the oxygen content at the surface was not increased after the corrosion test. X-ray diffractometry (XRD), field emission scanning electron microscopy ...
The production of cellulolytic enzymes from fungi has been extensively studied. Several mutants of Trichoderma reesei were selected. Most of the studies were carried out on T. reesei, T. viride, T. harzianum, Penicillium funiculosum, Altemaria alternata. Aspergillus phoenicis, A. ustus, A. tamarii, A. japonicus, and A. niger. T. koningii is one of the most active producers of the so-called C, factor, which is indispensable for the rapid and extensive attack on crystal-line cellulose. However, Trichodenna is known to excrete only small amounts of {beta}-glucosidase. Therefore, Trichoderma is supplemented with {beta}-glucosidase from Aspergillus to increase the saccharification rate of cellulose to glucose as the main sugar. Induction of mutations in Trichodenna spp. rather than T. viride as a tool for the enhancement of {beta}-glucosidase activity was reported. Unfortunately, T. reesei is a poor producer of {beta}-glucosidase. On the other hand, T. harzianum M{sub ...
Cell death in general can be a physiological process of cell number regulation in tissue, or it can be the result of exo or endogenous injuries, such a low-dose of radiation. Chicken B cell population in the bursa of Fabricius are very susceptible to PCD. Our present studies concern the development of radiation damage of chicken defence mechanisms. In 6 experiments pathogen free chicken were irradiated by gamma rays with the total doses of 0.25, 0.5, 1.0, 2.0 and 4.0 Gy. The induction of apoptosis was checked by Flow-cyto-meter 12 h after irradiation in bursa cell suspension. There is some increase in the number of induced apoptotic cells 12 h after irradiation at the dose 0.5-.4.0 Gy. There were no significant changes in the proportion of proliferating lymphocytes (G2 M), but cellularity decreased significantly at dose 2.0 and 4.0 Gy/12 h after irradiation. (author)
Protocols were standardized for in vitro propagation of several elite and diverse banana accessions using shoot tip explants. Tissue culture raised plants were field planted at multiple locations. Studies were undertaken for the induction of mutations using multiple shoot cultures of six selected cultivars, Shreemanti (AAA), Basrai (AAA), Lal Kela (AAA), Rasthali (AAB), Karibale Monthan (ABB) and a wild diploid (BB). These shoot cultures were irradiated at different doses of gamma rays (0-100 Gy) and subcultured thrice (up to M_1V_3) to separate shimeras, followed by induction of rooting (M_1V_4). In general, the rate of multiplication had a negative association with the dose of gamma rays. Enhanced multiplication of shoots was noticed at lower doses. The proliferation of shoots was arrested beyond 50 Gy and a dose of 70 Gy was completely lethal for all the genotypes studied. The rooted plantlets were hardened in the green house and in the ...
The NRL Long Pulse Induction Linac is being employed in a Free Electron Laser (FEL) experiment. The authors present results of beam transport and focusing experiments as well as measurements of the output radiation generated by various magnetic wigglers. The electron gun of the accelerator presently has a 17-cmdiam. cold cathode which is located in a nearly zero magnetic field (B /SUB z/ less than or equal to 5 G). The gun voltage is flat to within approx. = + or - 5% for 1.5 #mu#sec with this graphite brush cathode. The beam is focused by a series of solenoidal coils as it propagates through the 4-m-long accelerator."2 A solenoidal field which can be varied from 1-10 kG confines the beam in the FEL interaction region. Previous experiments were limited by poor beam transport, focusing, and matching into the relatively large solenoidal field in the FEL region. By smoothing the axial magnetic field profile in the accelerator and making a more adiabatic transition ...
Along with the shrinkage of LSI geometries, a higher quality of ultrapure water has been continuously required. Analytical technology for ultrapure water has also progressed before ultrapure water production technology improvements. In this study, we performed optimization of the analytical conditions for the direct analysis of acid droplets, and established an analytical technology for measurements of trace amounts of metallic impurities deposited on a wafer surface by means of Vapor Phase Decomposition (VPD)/Inductively Coupled Plasma Mass Spectrometry (ICP-MS). As a result, analytical technology for metallic elements of the 1x10"8 atoms/cm"2 level on wafer surface has been established. By applying analytical technology to the wafer that has been contacted with ultrapure water, a new evaluation technology for ultrapure water quality by means of wafer surface contamination has been established. We confirmed good correlations between metal contamination of the ...
Inductively coupled fluorocarbon (CF4/Ar and C4F8/Ar) plasmas were used to etch HfO2, which is a promising high-dielectric-constant material for the gate of complementary metal-oxide-semiconductor devices. The etch rates of HfO2 in CF4/Ar plasmas exceeded those in C4F8/Ar plasmas. The tendency for etch rates to become higher in fluorine-rich (high F/C ratio) conditions indicates that HfO2 can be chemically etched by fluorine-containing species. In C4F8/Ar plasmas with a high Ar dilution ratio, the etch rate of HfO2 increased with increasing bias power. The etch rate of Si, however, decreasd with bias power, suggesting that the deposition of carbon-containing species increased with increasing the power and inhibited the etching of Si. The HfO2/Si selectivity monotonically increased with increasing power, then became more than 5 at the highest tested bias power. The carbon-containing species to inhibit etching of Si play an important role in enhancing the HfO2/Si ...
Background: The effective-dose method which was proposed by the ICRP (International Commission of Radiation Protection) for the estimation of risk to the general population from occupational or environmental, low-dose radiation exposure is not adequate for estimating the risk of cancer induction by radiotherapy of malignant or nonmalignant diseases. Methods:The risk of cancer induction by radiotherapy of benign diseases should be based on epidemiologic data directly derived from follow-up studies of patients who had been given radiotherapy for nonmalignant diseases in the past. Results: Risk factors were derived from epidemiologic studies of patients treated with irradiation for nonmalignant diseases to be used for selecting treatment options and optimizing treatment procedures. Conclusion: In most cases, cancer risks estimated by the effective-dose method may overestimate the true risks by one order of magnitude, yet in other cases even may ...
Background: The effective-dose method which was proposed by the ICRP (International Commission of Radiation Protection) for the estimation of risk to the general population from occupational or environmental, low-dose radiation exposure is not adequate for estimating the risk of cancer induction by radiotherapy of malignant or nonmalignant diseases. Methods:The risk of cancer induction by radiotherapy of benign diseases should be based on epidemiologic data directly derived from follow-up studies of patients who had been given radiotherapy for nonmalignant diseases in the past. Results: Risk factors were derived from epidemiologic studies of patients treated with irradiation for nonmalignant diseases to be used for selecting treatment options and optimizing treatment procedures. Conclusion: In most cases, cancer risks estimated by the effective-dose method may overestimate the true risks by one order of magnitude, yet in other cases even may ...
Elise is a heavy ion induction linear accelerator that will demonstrate beam manipulations required in a driver for inertial fusion energy. With a line charge density similar to that of heavy ion drivers, Elise will accelerate a #>=# 1 gs beam pulse of K"+ ions from an initial energy of 2 MeV to a final energy #>=# 5 MeV. In the present design, the Elise electrostatic quadrupoles (ESQ) will have a 2.33 cm radius aperture operating at #+-#59 kV. The half-lattice periods range from 21 cm to 31 cm. The entire machine will be approximately 30 m long, half of that is the induction accelerator and the remaining half is the injector (including the Marx generator) and the matching section. Elise will be built in a way that allows future expansion into the full ILSE configuration, therefore it will have an array of four ESQ focusing channels capable of transporting up to a total of 3.2 A of beam current. Elise will also have an active alignment ...
In this work, the silicon oxynitride layer was studied as a tunneling layer for non-volatile memory application by fabricating low temperature polysilicon thin film transistors on glass. Silicon wafers were oxynitrided by only nitrous oxide plasma under different radio frequency powers and plasma treatment times. Plasma oxynitridation was performed in RF plasma using inductively coupled plasma chemical vapor deposition. The X-ray energy dispersive spectroscopy was employed to analyze the atomic concentration ratio of nitrogen/oxygen in oxynitride layer. The oxynitrided layer formed under radio frequency power of 150 W and substrate temperature of 623 K was found to contain the atomic concentration ratio of nitrogen/oxygen as high as 1.57. The advantage of high nitrogen concentration in silicon oxide layer formed by using nitrous oxide plasma was investigated by capacitance-voltage measurement. The analysis of capacitance-voltage characteristics demonstrated that ...
In this work, the silicon oxynitride layer was studied as a tunneling layer for non-volatile memory application by fabricating low temperature polysilicon thin film transistors on glass. Silicon wafers were oxynitrided by only nitrous oxide plasma under different radio frequency powers and plasma treatment times. Plasma oxynitridation was performed in RF plasma using inductively coupled plasma chemical vapor deposition. The X-ray energy dispersive spectroscopy was employed to analyze the atomic concentration ratio of nitrogen/oxygen in oxynitride layer. The oxynitrided layer formed under radio frequency power of 150 W and substrate temperature of 623 K was found to contain the atomic concentration ratio of nitrogen/oxygen as high as 1.57. The advantage of high nitrogen concentration in silicon oxide layer formed by using nitrous oxide plasma was investigated by capacitance-voltage measurement. The analysis of capacitance-voltage characteristics demonstrated that ...
The CYP1A (EROD)-inducing potencies of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), 3,3minutes or feet,4,4minutes or feet,5-pentachlorobiphenyl (PCB126) and benzo(k)fluoranthene (B(k)F) were studied in avian embryo livers. TCDD and PCB126 proved to be much more potent as inducers in the chicken than in the other species examined. This finding is consistent with a considerably higher sensitivity of the chicken compared with a number of other avian species to the embryotoxic effects of these compounds. Furthermore, the relative potencies of the tested Ah receptor agonists as CYP1A inducers differed substantially between species. B(k)F and PCB126 showed similar induction potencies in domestic duck embryos, whereas PCB126 is much more potent than B(k)F in the chicken. Also, the potency of PCB126,relative to that of TCDD, was much lower in quail embryo liver in vitro than in chicken embryo liver. Thus, there are large interspecific differences in birds in the sensitivity ...
To identify radio-protective agent candidate among medicinal plants and to elucidate the mechanism of action of the candidate material by using modern biochemical and molecular biological methods, we screened radio-protective activity among 48 medicinal plants. Seven samples showed above 20% protective activities against oxidative cell damage: Euryale ferox, Glycyrrhiza uralensis, Salvia miltiorrhiza, Eucomia ulmoides, Paeonia suffruticosa, Spirodela polyrrhiza, and Nelumbo nucifera. We also screened for oxidative stress sensitizing activity among other 51 medicinal plants. Among those samples, 11 samples showed good sensitizing effect; Melia azedarach, Agastache rugosa, Catalpa ovata, Prunus persica, Sinomenium acutum, Pulsatilla koreana, Oldenlandia diffusa, Anthriscus sylvestris, Schizandra chinensis, Gleditsia sinensis, and Cridium officinale. We also reported the radio-protective effect of DTT. The treatment of DTT increased cell survival after gamma-irradiation, decreased in the ...
2-hydroxyethyl methacrylate (HEMA) has been deposited onto the surface of silicon substrate (thickness = 500 ?m) using plasma polymerization technique. Polymerization process was carried out in an in-house developed inductively coupled plasma polymerization setup. The depositions were carried out using RF power supply (13.56 MHz) at power of 75 W for 10 and 40 min. The RF supply was coupled to the inductance through a matching network. The effect of plasma polymerization (surface grafting) on the degree of surface modification has been investigated. The chemical changes on the polymer backbone are followed from the results of Fourier transform infrared (FTIR) spectroscopy and X-ray photoelectron spectroscopy (XPS), which show the peaks corresponding to the functional groups of the HEMA polymerized onto the silicon surface. The morphology of the modified surfaces has also been investigated using scanning electron microscopy (SEM) and atomic ...
A new method for the determination of {sup 237}Np and Pu isotopes in large soil samples has been developed that provides enhanced uranium removal to facilitate assay by inductively coupled plasma mass spectrometry (ICP-MS). This method allows rapid preconcentration and separation of plutonium and neptunium in large soil samples for the measurement of {sup 237}Np and Pu isotopes by ICP-MS. {sup 238}U can interfere with {sup 239}Pu measurement by ICP-MS as {sup 238}UH{sup +} mass overlap and {sup 237}Np via {sup 238}U peak tailing. The method provides enhanced removal of uranium by separating Pu and Np initially on TEVA Resin, then transferring Pu to DGA resin for additional purification. The decontamination factor for removal of uranium from plutonium for this method is greater than 1 x 10{sup 6}. Alpha spectrometry can also be applied so that the shorter-lived {sup 238}Pu isotope can be measured successfully. {sup 239}Pu, {sup 242}Pu and {sup 237}Np were measured ...
This study develops a framework for analysis and assessment of the cost of ownership and use of major cooking appliances. This involved an assessment of the monetary cost as well as the cost of human resources required to maintain and operate cooking systems. The goal was to provide information useful in making purchase decisions within a framework that can be used to organize information about cost beyond the initial purchase price. Five cooktops - conventional electric oil, induction, solid element with thermostatic control, solid element with thermal limiter, and gas - and a microwave oven were used to develop a decision-making matrix. Results were used to assign weights in the matrix used to develop a 10-point scale that represented the total cost of owning and using a cooking system in food preparation. Based on the matrix, the microwave oven received the highest score followed by gas, conventional electric coil, solid element with thermostatic control, solid ...
Two plasma chemistries, i.e., CH_4/H_2/Ar and Cl_2/Ar, were compared for the etching of InGaP, AlInP, and AlGaP under inductively coupled plasma (ICP) conditions. While the etching with CH_4/H_2/Ar discharges appears to be ion driven, Cl_2/Ar discharges showed an additional strong chemical enhancement. The highest etch rate (#approx#1 #mu#m/min) for InGaP was achieved at high ICP source power (#>=#750 W) with the Cl_2/Ar chemistry. Cl_2/Ar discharges provided very smooth surfaces in all three materials with root-mean-square roughness measured by atomic force microscopy around 2 nm. This result may be due to the efficient ion-assisted product desorption in this chemistry. The etched near-surface region of InGaP (#approx#100 Angstrom) with Cl_2/Ar maintained almost the same stoichiometry as that of the unetched control. By contrast, the CH_4/H_2/Ar plasma chemistry produced somewhat rougher surfaces and depletion of phosphorous (P) from the surface of InGaP. ...
We reported the radio-protective effect of DTT. The treatment of DTT increased cell survival after gamma-irradiation, decreased in the frequencies of micronucleus, and reduction in DNA fragmentation and apoptotic cells. Induction of apoptosis after UV-C irradiation was revealed by the changes in the relative cell death, increase in the relative amount of apoptotic cells, and the induction of DNA fragmentation. About 100 medicinal plants were purchased and methanol extract samples were prepared. Radio-protective and radio-sensitizing activities of these samples were screened. Seven samples showed above 20% radio-protective activities: Salvia miltiorrhiza, Areca catechu, Cornus officinalis, Alpiniae officinari rhizoma, Meliae fructus, Alpiniae katsumadaii semen, Betulae cortex. Acanthopanax sessiliflous showed the highest radio-sensitizing effect and 10 other samples revealed moderate activities: Melia japonica, Agastache rugosa, Platycodon ...
Two series of diffusion tests were performed to examine the degradation of dichloromethane (DCM) as it diffuses through clay. The first series showed the use of a synthetic leachate with no significant initial bacterial population diffusing through a plug of intact clay; there was an induction period of 95--135 d, during which diffusion was as expected in the absence of degradation, followed by a second stage, where degradation occurred with an apparent half-life of less than 55 d at a temperature of 24 C. The second series of tests examined the diffusion of an actual leachate from the Keele Valley Landfill (KVL) (which provided both nutrients and a source of bacteria), through a compacted clay. In these tests, the induction period was reduced to 40--60 d, after which the apparent half-life was 20 d or less at 27 C. The diffusion coefficient for DCM was approximately 8 {times} 10{sup {minus}10} m{sup 2}/s, with partitioning coefficient K{sub d} ...
An electric propulsion concept suitable for delivering heavy payloads from low earth orbit (LEO) to high energy earth orbit is proposed. The system consists of a number of pulsed inductive plasma thrusters powered by a 100 kWe space nuclear power system. The pulsed plasma thruster is a relatively simple electrodeless device. It also exhibits adequate conversion to thrust power in the desired I sub sp regime of 1500 to 3000 seconds for optimal payload transfer from low earth to high earth orbit. Because of these features and the fact that the nuclear power unit will be capable of delivering sustained high power levels throughout the duration of any given mission, the system presented appears to be a very promising propulsion candidate for advanced orbital transfer vehicle (OTV) applications. An OTV, which makes use of this propulsion system and which has been designed to lift a 9000-lb payload into geosynchronous earth orbit, (GEO) is also examined.
A study of stress corrosion cracking susceptibility of Zircaloy-4 in chloride-containing aqueous methanolic media is presented. The influence of water content is investigated in the 5-100 vol. % water range. The dependence of stress corrosion cracking on potential is evidenced. A close correlation is established with pitting susceptibility determined by a statistical analysis of induction times. A correlation with the repassivation potential is observed in the water-rich solutions. In the low water content solutions, two repassivation curves are determined according to the experimental technique. Pit morphology and fractography show a transition from aqueous to organic media. (author).
Recent research work on adjustable speed pumped storage plants conducted in Japan, the USA and Europe suggests that they have many advantages over fixed-speed plants, and can contribute to power system regulation even in pump mode. This paper describes two types of static frequency converter for such pumped storage plants, especially those with greatly fluctuating heads. The design characteristics and operation of the doubly fed induction machine and the synchronous machine with DC link converter are set out and the devices compared. (UK)
Solenoid transport of high current, heavy ion beams is considered for several stages of a heavy ion fusion driver. In general this option is more efficient than magnetic quadrupole transport at sufficiently low kinetic energy and/or large e/m, and for this reason it has been employed in electron induction linacs. Ideally an ion beam would be transported in a state of Brillouin flow, i.e. cold in the transverse plane and spinning at one half the cyclotron frequency. The design of appropriate solenoids and the equilibrium and stability of transported ion beams are discussed. An outline of application to a fusion driver is also presented.
Introduction Gastrointestinal bleeding is a common life-threatening problem, causing significant mortality, costs and resource allocation. Its management requires a dynamic multidisciplinary approach that directs diagnostic and therapeutic priorities appropriately. Materials and methods Articles published within the past 15 years, related to gastrointestinal bleeding, were reviewed through MEDLINE search, in addition to current guidelines and standards. Results Decisions of ICU admission and blood transfusion must be individualized based on the extent of bleeding, hemodynamic profile and comorbidities of the patient and the risk of rebleeding. A secure airway may be required to optimize oxygenation and to prevent aspiration. Doses of induction agents must be reduced due to the changes in v...
We present a study of the interaction between Josephson junctions in circular superconducting rings and non-classical microwaves, treating both quantum mechanically. A Hamiltonian that describes both inductive and capacitive coupling between the two systems is derived within the external field approximation. Other Hamiltonians which go beyond the external field approximation, and describe explicitly the interaction of the quantum circuit that produces the non-classical microwaves with the Josephson junction circuit, are also presented. A comparison between current experiments which use classical electromagnetic fields and the proposed experiments that use non-classical microwaves, is made. (orig.) With 6 figs., 32 refs.
Fifty patients scheduled to undergo IVF received a standard anesthetic of fentanyl and propofol for induction, followed by propofol infusion, with Bispectral index values and modified Ramsey sedation scores recorded at 5-minute intervals for the duration of anesthesia care. Moderate sedation was found only transiently during the first 5-10 minutes of the oocyte retrieval, but thereafter the level of sedation increased, with deep sedation and general anesthesia measured in all patients as determined by both the Bispectral index scores and lack of response to painful stimulation.
Methods are described for the production of callus and subsequent shoot and root induction and multiplication using stamen filaments, nodes of young stems of mature trees or cotyledon petioles. A high frequency of contamination occurred using nodal sections from mature trees, whereas up to 100% sterility was obtained with cotyledons and stamens. The rooting % of shoot cultures from nodes or stamen callus was low compared with that of shoots from seedling callus. Considerable variation was observed between clones from different trees in their ability to produce shoots and roots. 27 references
Purpose: To prevent evaporization stills against corrosion due to radioactive liquid wastes. Constitution: Microwaves are supplied from a microwave generator by way of a wave guide tube and through a microwave permeation window to the inside of an evaporatization still. A matching device is attached to the wave guide tube for transmitting the microwaves in order to match the impedance. When the microwaves are supplied to the inside of the evaporization still, radioactive liquid wastes supplied from a liquid feed port by way of a spray tower to the inside of the evaporization still is heated and evaporated by the induction heating of the microwaves. (Seki, T.).
This review of methods and designs of transducers for nondestructive determination of the magnitude and nature of the anisotropy of magnetic properties (permeability, induction, coercive force, energy loss due to magnetization reversal) in local portions of ferromagnetic sheet and, in some cases, in individual parts of products. The need to measure the anisotropy is considered for two angles: for the case when the anisotropy is due to the crystallographic texture and determines the main operating characteristics of widely used sheet such as electrical steel and automobile body sheet, and for crystallographically isotropic materials, in which the anisotropy of magnetic properties as a result of mechanical stresses is a measure for determining the internal stresses.
Titanium metal-matrix composites (MMC) are prime candidate materials for aerospace applications be-cause of their excellent high-temperature longitudinal strength and stiffness and low density compared with nickel- and steel-base materials. This article examines the steps GE Aircraft Engines (GEAE) has taken to develop an induction plasma deposition (IPD) processing method for the fabrication of Ti6242/SiC MMC material. Information regarding process methodology, microstructures, and mechani-cal properties of consolidated MMC structures will be presented. The work presented was funded under the GE-Aircraft Engine IR & D program.
Studies on pupal irradiation of Earias vittella Fabricius, were undertaken to determine the optimum dose for sterile and competitive adults. Late pupae were irradiated with gamma radiation doses ranging from 150 to 300 Gy. Emerging adults were normal and without malformation. When males that emerged from irradiated pupae were crossed with normal female, fecundity as well as longevity was comparable to control, but there was drastic reduction in percent egg hatch in all the treatments. However, when females emerging from irradiated pupae were crossed with normal male, there was reduction in the fecundity as well as fertility and this effect was dose dependent. (author).
Several compounds were evaluated in nonhuman primates for their potential to induce neoplasms, especially hepatocellular carcinoma (HCC). The compounds can be classified into three groups: food contaminants, model rodent carcinogens, and nitrosamines. All three compounds in the food contaminants group, namely, aflatoxin B1, sterigmatocystin, and methylazoxymethanol acetate, induced HCC. None of the model rodent carcinogens tested consistently induced HCC in rhesus and cynomolgus monkeys. Three of four nitrosamines evaluated induced HCC in rhesus and cynomolgus monkeys. One nitrosamine, diethylnitrosamine, is a predictable and potent inducer of HCC and is useful for establishment of a nonhuman primate model for numerous oncologic studies.
Several fast neutral pressure gauges have been installed on NSTX [National Spherical Torus Experiment] to measure the vessel and divertor pressure during inductive and coaxial helicity injected (CHI) plasma operations. Modified, PDX [Poloidal Divertor Experiment]-type Penning gauges have been installed on the upper and lower divertors. Neutral pressure measurements during plasma operations from these and from two shielded fast Micro ion gauges at different toroidal locations on the vessel mid-plane are described. A new unshielded ion gauge, referred to as the In-vessel Neutral Pressure (INP) gauge is under development.
As a part of the program at the Lawrence Livermore National Laboratory (LLNL) in induction-linac free-electron laser (IFEL) research, the authors are conducting a variety of activities addressing the unique requirements imposed on IFEL wiggler systems. They are actively developing improved DC iron-core electromagnetic wiggler designs to attain higher peak fields, greater tunability, and lower random error levels. They are pursuing specialized control systems, such as magnetic-field and beam-position controllers, which can relax requirements on the wiggler itself. They are also pursuing basic studies to establish the effect of radiation on permanent magnets.
As a part of the program at the Lawrence Livermore National Laboratory (LLNL) in induction-linac free-electron laser (IFEL) research, we are conducting a variety of activities addressing the unique requirements imposed on IFEL wiggler systems. We are actively developing improved dc iron-core electromagnetic wiggler designs to attain higher peak fields, greater tunability, and lower random error levels. We are pursuing specialized control systems, such as magnetic-field and beam-position controllers, which can relax requirements on the wiggler itself. We are also pursuing basic studies to establish the effect of radiation on permanent magnets.
Earlier work carried out on the hydrogen-diesel dual-fuel engine indicates that knock sets in when the inducted hydrogen exceeds about 60% of input energy with a pilot quantity of 30% of full load diesel amount. Some of the findings of an investigation into knock-free performance of a hydrogen-diesel dual-fuel engine with the addition of a diluent-carbon dioxide are presented. The effects of carbon dioxide on the suppression of knocking in the hydrogen-diesel dual-fuel engine and on the improvement in the knock limited power output are described.
Drawing on work in epistemology and the philosophy of science, this paper seeks to provide very general reasons for why a comparative perspective needs to be applied to the inferential procedures of research methodologies where these concern the issue of justifying knowledge claims. In particular, the paper explores the role of culture on a number of important patterns of reasoning that figure in inferential arguments in research methodologies. The patterns examined are induction, both enumerative and analytical, hypothetico-deductive reasoning, and abductive inference. In each case it is argued that substantive theories about the world, including cultures, significantly affect inferential procedures. Examples chosen to illustrate this in more detail mostly reflect the impact of Confucian ...
Isotopic analyses of radioactive materials such as irradiated nuclear fuel are of major importance for the optimization of the nuclear fuel cycle and for safeguard aspects. Among the mass-spectrometric techniques available, inductively coupled plasma mass spectrometry (ICP-MS) and thermal ionization mass spectrometry are the most frequently applied methods for nuclear applications. Because of the low detection limits, the ability to analyze the isotopic composition of the elements and the applicability of the techniques for measuring stable as well as radioactive nuclides with similar sensitivity, both mass-spectrometric techniques are an excellent amendment to classical radioactivity counting methods. The paper describes selected applications of multicollector ICP-MS in combination with c...
Male meadow voles maintained in a long photoperiod (LP) from birth have heavier brains than do females, but in short photoperiods (SP) this sex dimorphism is absent. Testosterone propionate (TP) administration on the second day of postnatal life produced significant increases in brain weight of LP but not SP females at 35 days of age. Short daylengths reduce the responsiveness of the meadow vole nervous system to the masculinizing effects of perinatal testosterone and may, in part, mediate the seasonally reduced sex difference in brain weight. PMID:8446686
A high-power microwave Free Electron Laser (FEL) experiment has been performed to study the inherent electron beam bunching that occurs in the FEL interaction. An induction linac delivered a 1 kA, 2.2 MeV electron beam to a FEL amplifier. In the process of amplifying the input signal of frequency 35 GHz to power levels of the order of 10 MW, the electron beam was bunched by the ponderomotive force. In this paper we describe the FEL experiment and the optical technique that was used to observe the bunches. Their properties as functions of the basic FEL parameters are discussed. copyright 1996 American Institute of Physics.
The mutual inductance between parallel transmission lines influences the locating of the transmission line faults. A fault location algorithm for parallel lines developed in this paper takes into account the magnetic coupling between parallel lines. The paper presents a detailed description of the developed algorithm and test results performed on a simplified real transmission line. The obtained error is less than 0.5 percent in most cases. Also, the developed algorithm is not sensitive to typical fault parameters, such as: resistance, type, location, and incidence angle. 7 refs, 4 figs, 12 tabs
We report the case of a 22-year-old man with Ewing's sarcoma who attained a complete remission (CR) after combination radiotherapy and chemotherapy. Secondary acute lymphoblastic leukemia with multiple cytogenetic abnormalities involving chromosome 5 and 7 developed 16 years later. The patient underwent induction chemotherapy and entered a CR. Peripheral blood stem cell transplantation from a matched sibling was performed successfully and he is in complete remission of both ALL and Ewing's sarcoma. (Copyright (c) 1999 Elsevier Science B.V., Amsterdam. All rights reserved.)
A new simple multi-well plate-based assay to determine monocyte differentiation-inducing activity was developed. It is based on the increase of macrophage adherence after the induction of monocyte differentiation. The assay was conducted using a human monocytic leukemia cell line, THP-1, treated with either 12-O-tetradecanoylphorbol 13-acetate or cytokines, such as tumor necrosis factor-alpha and interferon-gamma. This method is sensitive and easy to perform, especially in case of analyzing a large number of samples. PMID:17920620
A new simple multi-well plate-based assay to determine monocyte differentiation-inducing activity was developed. It is based on the increase of macrophage adherence after the induction of monocyte differentiation. The assay was conducted using a human monocytic leukemia cell line, THP-1, treated with either 12-O-tetradecanoylphorbol 13-acetate or cytokines, such as tumor necrosis factor-? and interferon-?. This method is sensitive and easy to perform, especially in case of analyzing a large number of samples.
The effect of 50 Hz and 60 Hz (frequencies of current distribution) and 20 kHz to 50 kHz (frequencies of induction cooktop) magnetic interference on implanted pacemakers have been assessed with the present generation of device technology. Sixty patients implanted in 1998 and 1999 with dual chamber pacemakers from 9 different manufacturers were monitored with telemetry while passing through, and standing between a system of two coils. They generated a 50 Hz or a 60 Hz magnetic field at 50 microT. Then, patients used a cooktop at different power. The recordings were made with the standard setting of "medically correct" sensing parameters chosen for the patients. Then pacemakers were reprogrammed to the unipolar mode, with the highest atrial (A) and ventricular (V) sensitivity that did not induce muscular inhibition while moving. Between each exposure (50 Hz, 60 Hz or 20 kHz to 50 kHz), the pacemaker programmation was controlled. At the end of the tests, pacemakers ...
The Segmented Rail Phased Induction Motor (SERAPHIM) is a compact, pulsed linear induction motor (LIM) offering a unique capability for very high speed train propulsion. It uses technology developed for the Sandia coilgun, an electromagnetic launcher designed to accelerate projectiles to several kilometers per second. Both aluminum cylinders and plates were accelerated to a kilometer per second (Mach 3) by passing through a sequence of coils which were energized at the appropriate time. Although this technology was developed for ultra-high velocity, it can be readily adapted to train propulsion for which, at sea level, the power required to overcome air resistance limits the operational speed to a more modest 300 mph. Here, the geometry is reversed. The coils are on the vehicle and the ``projectiles`` are fixed along the roadbed. SERAPHIM operates not by embedding flux in a conductor, but by excluding it. In this propulsion scheme, pairs of ...
High quality single-walled carbon nanotubes (SWNT) have been synthesized at large scales by the method of direct evaporation of carbon black and metallic catalyst mixtures, using induction thermal plasma technology. The processing system consists mainly of an RF plasma torch, which generates a plasma jet of extremely high temperature (?15 000 K), with a high energy density and abundance of reactive species (ions and neutrals). With the present reactor system, it has been demonstrated that carbon soot product which contains approximately 40 wt% of SWNT can be continuously synthesized at the high production rate of ?100 g h-1. The processing parameters involved have been examined closely in order to evaluate their individual influences on SWNT synthesis. The results have shown that the quality and purity of the SWNT produced are critically affected by the grade of carbon black, the plasma gas composition and the metallic catalyst employed. Theoretical calculations, ...
Peroxisome proliferating agents (PPAs) are a structurally diverse group of chemicals that include environmental chemical contaminants such as certain chlorinated herbicides, solvents and plasticizers. PPAs have previously been shown to induce anti-trout laruci acid hydroxylase immunoreactive proteins in bluegill and catfish. In this investigation, induction of lauric acid hydroxylase activity and immunoreactive proteins was confirmed, and the mass spectral analysis of specific hydroxylation products was performed in order to identify possible species-specific differences in fatty acid metabolism. Male bluegill (Lepomis macrochirus) and channel catfish (Ictalurus punctatus) were administered clofibrate or ciprofibrate 48 hr prior to hepatic or trunk kidney (catfish only) microsome preparation. While no significant differences were observed in male catfish, male bluegill had significant decreases in hematocrit and plasma protein indicating hemodilution due to ...
The /sup 13/C-AP breath test is shown to be a convenient, noninvasive method to monitor velocity and capacity of P450-dependent AP N-demethylation in infancy and childhood. According to /sup 13/C-AP breath tests, neonates have a very low capacity to eliminate /sup 13/CO/sub 2/, which is only 15 to 21% of the activity in adults. During the first year of life AP N-demethylation increases to reach its maximum at about 2 years; afterwards a slight decrease occurs. In 25 neonates exposed prenatally to different antiepileptic drugs /sup 13/C-AP breath test was efficiently used to prove that cytochrome AP N-demethylation was considerably stimulated. After primidone/phenobarbitone, especially in combination with phenytoin, /sup 13/C elimination reaches and even surpasses the range for older children. Valproate exposure during fetal life is not consistently followed by a significant increase in AP N-demethylation. The enzyme induction demonstrated by /sup 13/C-AP breath ...
Purpose To investigate the sensitivity and accuracy of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) for restaging the mediastinum after induction chemotherapy in patients with non-small-cell lung cancer (NSCLC). Patients and Methods One hundred twenty-four consecutive patients with tissue-proven stage IIIA-N2 disease who were treated with induction chemotherapy and who had undergone mediastinal restaging by EBUS-TBNA were reviewed. On the basis of computed tomography, 58 patients were classified as having stable disease and 66 were judged to have had a partial response. All patients subsequently underwent thoracotomy with attempted curative resection and a lymph node dissection regardless of EBUS-TBNA findings. Results Persistent nodal metastases were detected by using EBUS-TBNA in 89 patients (72%). Of the 35 patients in whom no metastases were assessed by EBUS-TBNA, 28 were found to have residual stage IIIA-N2 ...
1-Furan-2-yl-3-pyridin-2-yl-propenone (FPP-3) is an anti-inflammatory agent with a propenone moiety and chemically synthesized recently. In this study, we examined the chemopreventive effect of FPP-3 on 7,12-dimethylbenz[a]anthracene (DMBA)-induced genotoxicity in MCF-7 cells. FPP-3 reduced the formation of the DMBA-DNA adduct. DMBA-induced CYP1A1 and CYP1B1 gene expression and enzyme activity were inhibited by FPP-3. It inhibited DMBA-induced aryl hydrocarbon receptor (AhR) transactivation and DMBA-inducible nuclear localization of the AhR. Induction of detoxifying phase II genes by chemopreventive agents represents a coordinated protective response against oxidative stress and neoplastic effects of carcinogens. Transcription factor NF-E2 related factor 2 (Nrf2) regulates antioxidant response element (ARE) of phase II detoxifying and antioxidant enzymes, such as glutathione S-transferase (GST) and NAD(P)H:quinone oxidoreductase (QR). FPP-3 increased the expression ...
We analyzed the effect of short-term water deficits at different periods of sunflower (Helianthus annuus L.) leaf development on the spatial and temporal patterns of tissue expansion...Full Text Available
Effector proteins expressed in the esophageal gland cells of cyst nematodes are delivered into plant cells through a hollow, protrusible stylet. Although evidence indicates that effector proteins function...Full Text Available
BackgroundTransposons, i.e. transposable elements (TEs), are the major internal spontaneous mutation agents for the variability of eukaryotic genomes. To address the general issue...Full Text Available
Expressions for the spatial moments and macrodispersion tensor for sorbing solutes in heterogeneous formations were presented using a probabilistic model of a fluid residence time coupled with the particle position analysis. The fluid residence time was defined as a fraction of the actual time during which the particle stayed in the mobile fluid phase of the aquifer. The fluid residence time is a random variable whose variability comes as a result of the non-equilibrium sorption properties. The sorbing solute was assumed to be governed with first-order linear kinetics. The closed-form expressions were based on the stationarity in the kinetic process and on the first-order approximation in the hydraulic conductivity field and in the fluid residence time. The non-equilibrium effects were presented as a function of the spatial variability in hydraulic conductivity and temporal variability in the fluid ...
The paralysis-by-analysis phenomenon, i.e., attending to the execution of one's movement impairs performance, has gathered a lot of attention over recent years (see Wulf, 2007,...Full Text Available
Activation-induced deaminase (AID) initiates somatic hypermutation, gene conversion and class switch recombination by deaminating variable and switch region DNA cytidines to uridines. AID is predominantly...Full Text Available
Intraindividual variability of measurements of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), nicotine, cotinine, and r-1,t-2,3,c-4-tetrahydroxy-1,2,3,4-tetrahydrophenanthrene...Full Text Available
A previous report of high levels of members of the domain Archaea in Antarctic coastal waters prompted us to investigate the ecology of Antarctic planktonic prokaryotes. rRNA hybridization...Full Text Available
BackgroundSynonymous sites are freer to vary because of redundancy in genetic code. Messenger RNA secondary structure restricts this freedom, as revealed by previous findings in...Full Text Available
Dependent variables in research on problem behavior typically are based on measures of response repetition, but these measures may be problematic when behavior poses high risk or when its occurrence...Full Text Available
IntroductionHealth information on the Internet undergoes no quality control at the stage of production, thus its quality is highly variable, making it difficult...Full Text Available
Information from the Health Assessment Questionnaire (HAQ) is used to identify which variables measured in 1981 successfully predict the severity of disease in 1989 and the eight year change in severity...Full Text Available
Dissecting the genes involved in complex traits can be confounded by multiple factors, including extensive epistatic interactions among genes, the involvement of epigenetic regulators, and the variable...Full Text Available
BackgroundAn earlier study showed that a week of yoga practice was useful in stress management after a natural calamity. Due to heavy rain and a rift on the banks of the Kosi river,...Full Text Available
The highly variable and intermittent pollutant concentrations and flowrates associated with wet-weather events in combined sewersheds necessitates the use of storage-treatment systems to control pollution.An optimized combined-sewer-overflow (CSO) control system requires a manage...
Using the POLISH instrument, I am unable to reproduce the large-amplitude polarimetric observations of Berdyugina et al. (2008) to the >99.99% confidence level. I observe no significant polarimetric variability in the HD 189733 system, and the upper limit to variability from the exoplanet is Delta_P < 7.9 x 10^(-5) with 99% confidence in the 400 nm to 675 nm wavelength range. Berdyugina et al. (2008) report polarized, scattered light from the atmosphere of the HD 189733b hot Jupiter with an amplitude of two parts in 10^4. Such a large amplitude is over an order of magnitude larger than expected given a geometric albedo similar to other hot Jupiters. However, my non-detection of polarimetric variability phase-locked to the orbital period of the exoplanet, and the lack of any significant variability, shows that the polarimetric modulation reported by Berdyugina et al. (2008) cannot be due to the ...
The effect of spatial auditory information on a listener's ability to detect, identify, and monitor multiple simultaneous speech signals was evaluated using virtual audio technology. Factorial combinations of three variables - the number of localized spee...
The sequence-dependent structural variability and conformational dynamics of DNA play pivotal roles in many biological milieus, such as in the site-specific binding of transcription factors to target...Full Text Available
The sequences of the internal transcribed spacer (ITS) ribosomal DNA (rDNA) domain data obtained by restriction fragment length polymorphism analysis with 18S rDNA and fingerprinting (M13) for clinical...Full Text Available
Despite the demonstrated clinical efficacy of CD20 monoclonal antibody (mAb) for lymphoma therapy, the in vivo mechanisms of tumor depletion remain controversial and variable. To identify the molecular...Full Text Available
Study objectiveThe study aim was to improve our understanding of the relationships between contextual socioeconomic characteristics and coronary heart disease (CHD)...Full Text Available
Simulations with a regional chemical transport model show that anthropogenic emissions of volatile organic compounds and nitrogen oxides (NOx = NO + NO2) lead to a dramatic diurnal...Full Text Available
ObjectiveTo develop consistent variable names and a common database structure for the data elements in the International Spinal Cord Injury (SCI) Data Sets.Full Text Available
Random forest (RF) analysis of genetic data does not require specification of the mode of inheritance, and provides measures of variable importance that incorporate interaction effects. In this paper...Full Text Available
Although humans vary in their response to chemicals, comprehensive measures of susceptibility have generally not been incorporated into human risk assessment. The U.S. EPA dose-response-based risk assessments...Full Text Available
In this review we attempt to reconstruct the evolutionary history of hominin life history from extant and fossil evidence. We utilize demographic life history theory and distinguish life history variables,...Full Text Available
Arbuscular mycorrhizal fungi (AMF) are ecologically important root symbionts of most terrestrial plants. Ecological studies of AMF have concentrated on differences between species; largely assuming...Full Text Available
High speed experimental tests provided data on six parametric cylindrical roller bearings. Four bearing variables were evaluated and the results were correlated with the analytical model developed under Naval Air Propulsion Center Contract N00140-76-C-038...
An approach to the calculation of the quantity of heat consumed in the process of coal formation is presented. The variability of this parameter in a coalification series is analyzed using coals from the Kuznetsk and Tunguska Basins as an example.
The systems for which the algebra of gauge transformations in the lagrangian formalism is closed, are considered. The hamiltonian BRST charge and the BRST-invariant hamiltonian are found explicitly. Their expansions in powers of the ghost variables contain, in general, an infinite number of terms. (orig.).
Glossitis among U.S. military working dogs in South Vietnam was characterized by variable redness and loss of papillae on the anterodorsal third of the tongue; salivation, drooling, and inappetence were the principal clinical signs. Symptomatic treatment ...
The torque-velocity relationship is known to be affected by ageing, decreasing its protective role in the prevention of falls. Interindividual variability in this torque-velocity relationship is partly...Full Text Available
Despite their status as the most speciose group of terrestrial vertebrates, birds exhibit the smallest and least variable genome sizes among tetrapods. It has been suggested that this is because powered...Full Text Available
Exercise is essential for health, yet the amount, duration, and intensity that individuals engage in are strikingly variable, even under prescription. Our focus was to identify the locations and effects...Full Text Available
Microarray data has a high dimension of variables but available datasets usually have only a small number of samples, thereby making the study of such datasets interesting and challenging. In the task...Full Text Available
The aim of the present study focuses on experimentally demonstrating the efficacy of using angularly-variable fiber geometry to achieve the desired tissue-layer selection and probing depths with the further objective of enhancing the sensitivity and specificity of spectral diagnosis in stratified architectures that resemble human cervical epithelia. The morphological and biochemical features of epithelial tissue vary in accordance with tissue depths; consequently, the accuracy of spectroscopic diagnosis of epithelial dysplasia may be enhanced by probing the optical properties of this tissue. When correlated to cellular dysplasia, layer-specific changes in tissue optical properties may be deciphered by reflectance spectroscopy coupled with angularly-variable fiber geometry. This study addresses the utility of using such angularly-variable fiber geometry for resolving spatially-specific spectral signatures of tissue ...
We investigated the effects of wastewater treatment plant (WWTP) discharge on the ecology of bacterial communities in the sediment of a small, low-gradient stream in South Australia. The quantification...Full Text Available
... 1984; Martin-Mora et al., 1995), and parasitism (Rothschild and Rothschild, 1939; Pesigan et al., 1958; Moose, 1963; Pan, ... effects of digeneans are variable; they may enhance (Rothschild and Rothschild...
Understanding the pathogenesis of obesity is now more important than ever, given the remarkable world-wide epidemic. This paper explores the potential role of core temperature in energy balance, and...Full Text Available
Energy confinement in W7-AS has been analyzed in terms of dimensionally exact form free functions employing Bayesian probability theory. The confinement function was set up as a linear combination of dimensionally exact power law terms as already proposed very early by Connor and Taylor. Generation of this expansion basis is dictated by the basic plasma model which one assumes. Based upon data accumulated in W7-AS, which contains the energy content for a wide variety of variable settings, predictions for single variable scans are made. The scaling functions for density and power scans, respectively, are in quantitative agreement with data collected in W7-AS. The result of a single variable scan is therefore already hidden in the data obtained for arbitrary variable choices and can be extracted from the latter by a proper data analysis. Furthermore, the optimal model for the description of the global ...
Detrended fluctuation analysis (DFA) is a recently developed technique suitable for describing scaling behavior of variability in physiological signals. The purpose of this study is to explore...Full Text Available
Certain structural and environmental factors other than technical combination of resources and firm size are hypothesized to affect medical practice output. Four groups of variables related to physician...Full Text Available
BackgroundStudies conducted in developed countries using economic models show that individual- and household- level variables are important determinants of health insurance ownership....Full Text Available
In recent years the modelling of interannual climate variability has been studied, the atmospheric energy and water cycles, and climate simulations with the ECHAM3 model. In addition, the climate simulations of several models have been compared with special emphasis in the area of northern Europe
BackgroundInadequate platelet inhibition despite aspirin and clopidogrel therapy during and after a percutaneous coronary intervention is associated with an impaired clinical outcome....Full Text Available
In this report, the main emphasis is given to (1) the problems associated with the basic calibration of the spectroradiometer and (2) the year-to-year variability of the calibrations of the solar UV network radiometers. Also, the results from intercomparisons of the Brewer and OL 742 spectroradiometers are included
PurposeTo analyze the contributions of cytochrome P4501B1 (CYP1B1) mutations to primary congenital glaucoma (PCG) in Spanish patients.MethodsWe...Full Text Available
An elliptic equation in a rectangle with coefficients depending on a fast variable and with its period being a small parameter is considered. An asymptotic expansion of the solution up to an arbitrary degree of the small parameter is constructed and substantiated by applying the two-scale expansion method.
After discrimination training on a multiple variable-interval extinction schedule of food reinforcement, pigeons were placed on the uncued or mixed version of the same schedule and allowed to make...Full Text Available
Visual assessment of the degree of renal artery stenosis on renal arteriography has a large inter- and intraobserver variability. This degree is usually estimated by the ratio between the most narrowed...Full Text Available
BackgroundMost analyses of spatial clustering of disease have been based on either residence at the time of diagnosis or current residence. An underlying assumption in these analyses...Full Text Available
Antiplatelet resistance has been proposed as a possible mechanism to explain recurrent cardiovascular events in patients who have coronary artery disease and who are undergoing dual antiplatelet therapy....Full Text Available
In the case wherein nonlinear seismic response analyses are carried out, the response values vary due to the variations in materials and modeling. In this paper, nonlinear analyses of several random variables are carried out using: i. a conventional method; ii. a two-point estimation method (i. and ii. are simplified methods); and iii. Monte Carlo simulation (detailed method) to examine the variability of the response in the excessive nonlinear range for seismic responses of shear walls. The analyses are performed to a PWR-3 loop type reactor building which is one of the most typical reactor buildings in Japan. The variations are considered in specified compressive strength of concrete, concrete damping factor, shear wave velocity of soil and shapes of shear stress-strain relation curves of shear walls. As the results by the two simplified methods closely matched the Monte Carlo simulation results, the appropriateness for applying the ...
BackgroundTraditionally in pediatric HIV, the CD4+ T-lymphocyte percent is used in monitoring disease progression due to the variability in absolute CD4+ T-lymphocyte...Full Text Available
The distribution of 20 variable regions resulting from insertion-deletion events in the genomes of the tubercle bacilli has been evaluated in a total of 100 strains of Mycobacterium tuberculosis,...Full Text Available
PurposeTo detail the highly variable ocular phenotypes of a French family affected with an autosomal dominantly inherited vitreoretinopathy and to identify the disease gene.MethodsSixteen...Full Text Available
BackgroundWith the explosion in data generated using microarray technology by different investigators working on similar experiments, it is of interest to combine results across...Full Text Available
Structural variants which cause changes in copy numbers constitute an important component of genomic variability. They account for 0.7% of genomic differences in two individual genomes, of which...Full Text Available
A variable-dispersion electron spectrometer is being installed for use by the Stanford Superconducting Accelerator in conjunction with its Free Electron Laser program. The system has been designed to operate with electron beam energies from 20 MeV to 200 MeV, with a maximum energy resolution of 0.01% FWHM. The maximum energy acceptance is approximately #+-# 5%, as determined by the bending magnet aperture. Resolution is controlled by adjusting the focal conditions at the entrance to a 90 degree bending magnet, while the dispersion is controlled by changing the magnitude and polarity of the field in a quadrupole magnet which immediately follows the bending magnet. 4 refs., 5 figs.
This report describes the design, fabrication, installation and testing of a small variable-speed vertical axis wind turbine (VAWT). This VAWT is unique in its installation using hand tools only; unconventional and simple support system; and variable speed operation under microprocessor control. Initial testing confirmed that the turbine can be controlled by commanded alternator field modulation. Further studies will be directed toward determination of an optimum control algorithm.
Divergence between aircraft engine emission regulations proposed by EPA and ICAO is discussed. Every engine, upon entering service, requires a certificate as to its compliance with emission standards. It is shown that despite the large variability in the measurements, it is possible to devise a certification procedure requiring the testing of one engine only. Statistical modeling of such a test at the 5% significance level is described. Values of the parameter standard deviation/mean recommended as certification standards for various pollutants are given. Features of a rational certification scheme to be formulated are outlined.
We construct representation of the Separated Variables (SoV) for the quantum SL(2,R) Heisenberg closed spin chain and obtain the integral representation for the eigenfunctions of the model. We calculate explicitly the Sklyanin measure defining the scalar product in the SoV representation and demonstrate that the language of Feynman diagrams is extremely useful in establishing various properties of the model. The kernel of the unitary transformation to the SoV representation is described by the same "pyramid diagram" as appeared before in the SoV representation for the SL(2,C) spin magnet. We argue that this kernel is given by the product of the Baxter Q-operators projected onto a special reference state.
For reliable operation and the optimization of production, industrial fermentation processes require appropriate tools for monitoring the process in real time. This work presents the structure and operation of a soft sensor for the on-line monitoring of biomass and product concentration during salinomycin and bacitracin fermentation in an industrial, 80-m^3 batch reactor; moreover it provides a tool for evaluation of batch production verified in industrial application. The process estimation algorithm consists of decoupled growth and product models, which ensures an unbiased convergence of the estimator and the robustness of the model. The production of secondary metabolites is described with a non-structured model upgraded with a variable forgetting factor that demonstrated a successful e...
The idle speed of an internal combustion engine is controlled in response to a variable ignition timing control signal from a microcomputer. The microcomputer derives this control signal as a function of the magnitude of engine speed variation which occurs during engine idle periods to cause the ignition timing to vary quickly in response to a transitory engine load variation. An auxiliary air delivery system may be advantageously incorporated in the idle speed control system to cooperate with the ignition timing control in response to the engine speed variation.
The marine ram-type blowout preventer deployed from an offshore drilling rig has one serious disadvantage, its inaccessibility. A development to promote reliability of the subsea ram-type preventer and reduce the excess running and pulling to charge out rams, is the variable bare ram (VBR). Unlike the standard ram, the VBR has the ability to pack off a range of pipe sizes. Interest in VBR's has been revived and research and development in this equipment goes on at each of three manufacturer's facilities in Houston.
We discuss the inclusive production of D{sup *{+-}} mesons in {gamma}p collisions at DESY HERA, based on a calculation at next-to-leading order in the general-mass variable-flavor-number scheme. In this approach, MS subtraction is applied in such a way that large logarithmic corrections are resummed in universal parton distribution and fragmentation functions and finite mass terms are taken into account. We present detailed numerical results for a comparison with data obtained at HERA and discuss various sources of theoretical uncertainties. (orig.)
We consider the spin-up of the white dwarf in non-magnetic cataclysmic variables (CVs) during secular evolution. If this is unresisted, CVs are quenched as boundary-layer emitters once the binary period has decreased by #approx# 1 hr. Angular momentum loss in nova explosions may, however, prevent the star reaching breakup. If the explosions remove (1 + #epsilon#) x the mass accreted between outbursts, values 0.5 < #approx# #epsilon# < #approx# 1 allow CVs to be modest boundary-layer emitters for most of their lifetimes. Spectral effects will limit their detection as soft X-ray sources. (author).
Energy productivity and energy intensity within the industrial sector of the economy are examined. Results suggest that relative prices and other economic factors can explain much of the variation in both energy productivity and energy intensity for manufacturing and mining and for the industrial sector as a whole. Cyclical factors, seasonal factors and trend variables are also useful in explaining variation in these data, both for annual and monthly time series. Of the variables examined, it appears that the relative price of energy is a highly significant factor in accounting for the difference between actual industrial energy intensity and that which might have been expected had pre-1973 trends continued.
The effects of variable hardness, pH, alkalinity, humics, and suspended clay on the chemical speciation of copper and its toxicity to fathead minnow larvae in Lake Superior water were investigated. Two proposed methods (toxicity factors and chemical speciation) for predicting LC50 values in specific natural waters from laboratory toxicity data and the average site specific values of general water quality parameters were evaluated. The accuracy of the cupric ion-selective electrode in determining CU/sup +2/ activities in ambient and chemically altered Lake Superior water was also determined.
We present a protocol for quantum key distribution using discrete modulation of coherent states of light. Information is encoded in the variable phase of coherent states which can be chosen from a regular discrete set ranging from binary to continuous modulation similar to phase-shift keying in classical communication. Information is decoded by simultaneous homodyne measurement of both quadratures and requires no active choice of basis. The protocol utilizes either direct or reverse reconciliation both with and without postselection. We analyze the security of the protocol and show how to enhance it by the optimal choice of all variable parameters of the quantum signal.
In this project we determined primary production and optical variability in the shelf and slope waters off of Cape Hatteras, N.C. These processes were addressed in conjunction with other Ocean Margins Program investigators, during the Spring Transition period and during Summer. We found that there were significant differences in measured parameters between Spring and Summer, enabling us to develop seasonally specific carbon production and ecosystem models as well as seasonal and regional algorithm improvements for use in remote sensing applications.
A fermionic - based on Grassmann--Berezin calculus of anticommuting variables - topological quantum field theory (TQFT) is considered, mainly in three dimensions. It is defined for piecewise-linear manifolds and, for a given triangulation, deals only with a finite number of variables. Despite its simple nature, it can distiguish between lens spaces L(7,1) and L(7,2). And despite its origin from a kind of Reidemeister torsion, it does this without using nontrivial representations of the fundamental group. Also, symbolic calculations are presented giving strong evidence of existence of similar theory in four dimensions.
Pippenger (2011) recently proposed a solution to the longstanding forward-bias puzzle. He argues that the puzzling estimates obtained using the standard equation for the efficient markets hypothesis are due to omitted variable bias. He identifies the missing variables as the future change in the forward exchange rate and the future interest differential. When these are added to the standard equation, he finds a one-to-one relationship between the future change in the spot rate and the forward premium. However, we argue that his equation can only test covered interest parity and offers no insight into the forward-bias puzzle.
A reliability approach for probabilistic modeling of one-dimensional non-reactive and reactive transport in porous media provides two important quantitative results: (1) an estimate of the probability that dimensionless concentration equals or exceeds some specified level and, (2) the sensitivity of the probabilistic outcome to likely changes in each uncertain variable. The reliability approach is particularly attractive because it can incorporate various marginal probability density functions (PDF) for any of the uncertain variables. In this work uncertain variables include: groundwater flow velocity, diffusion coefficient, dispersivity, distribution coefficient, porosity and bulk density. The primary objective is to examine how the probabilistic outcome is influenced by choice of marginal PDF, correlation and magnitude of uncertainty for the variables. Because little information exists concerning the ...
Autonomous robots or remotely operated vehicles have raised high hopes in the military and industrial communities because of the potential safety improvement and gain of productivity they may provide. Waste management on nuclear sites, pallet manipulation in factories, interventions on battle-fields, etc., are actively studied. A lot of these applications require powerful four-wheel vehicles, the kinematics of which is similar to that of a car. Such vehicles have three degrees of freedom: the (x,y) positions in a plane and the orientation of the vehicle. Path planning is often understood as only changing the position of the vehicle, whereas the tasks performed by this kind of robot requires a perfect orientation of the vehicle: forklifting a pallet or docking at a loading or unloading station requires accuracy in the orientation of the vehicle. It is this requirement and the kinematic constraints of the motion mode which have led to the path-planning algorithm presented in this paper. ...
The Pequop Mountains (PM), Wood Hills (WH) and East Humboldt Range (EHR), NE Nevada, provide evidence that the hinterland of the Sevier thrust belt experienced large-magnitude Mesozoic shortening ([>=]55 km) and crustal thickening ([>=] 30 km). These ranges expose a structurally continuous crustal cross section of unmetamorphosed to high pressure upper amphibolite facies Triassic to Precambrian miogeoclinal strata. This sequence lies structurally beneath unmetamorphosed extensional klippen that omit metamorphic grade and crustal section, but also repeat stratigraphic units. Because they repeat stratigraphic units, the underlying miogeoclinal section, or footwall, must have once lain beneath a thrust fault (herein named the Windermere thrust). The footwall of the Windermere thrust was exhumed by two generations of top-to-the-W-NW low-angle normal faults that are distinguished by whether they are depositionally overlapped by Eocene volcanic rocks or if they cut the volcanic rocks ...
Seismic stratigraphy based chronostratigraphic (SSBC) analysis of the Serbian Banat region allows the delineation of the spatial and stratigraphic relationships of the generally regressive and shallowing upward Neogene depositional fill of a tectonically unstable central portion of the Pannonian Basin. When geometrically restored in time and space, the sediment dispersal directions, sediment source directions, types of sedimentation breaks and the tectonic events influencing basin evolution can be delineated. For such an analysis the time-transgressive lithostratigraphic units used in the neighbouring Hungarian part of the Pannonian Basin are conveniently introduced based upon their characteristic seismic facies and constrained borehole log records as mappable seismic stratigraphic sequence units, termed "seismic operational sequences". The respective Neogene stage and operational sequence equivalents (Hungarian lithostratigraphic units or formations) are the Middle Miocene (Badenian, ...
A numerical study has been performed to investigate the hydrodynamic aspects of the pool boiling on horizontal-, vertical- and downward-facing surfaces. The FlowLab code, which is based on a Lattice-Boltzmann (LB) model of two-phase flows, is employed. Macroscopic properties, such as surface tension ({sigma}) and contact angle ({beta}), are implemented through the fluid-fluid (G{sub {sigma}}) and fluid-solid (G{sub t}) interaction potentials. The model is found to express a linear relation between the macroscopic properties ({sigma}, {beta}) and microscopic parameters (G{sub {sigma}}, G{sub t}). The simulation results on bubble departure diameter appear to have the same parametric dependence as the empirical correlation. Hydrodynamic aspects of two-phase flow regime transition mechanism are investigated for different surface-coolant configurations. Results of the LB simulation clearly demonstrate that not only the bubble nucleation site density (related, e.g. to the heater surface ...
Gabal Ralal is one of the major asymmetrical doubly- plunging anticlinal fold belts (50 Km length) related to the Syrian Arc System in northern Sinai, Egypt. The exposed rock units at Gabal Ralal range from Cretaceous to Quaternary and are divided into eight formations which are from base to top: Malha, Ralal, Wata, Themed, Sudr, Beida, Egma and Quaternary wadi deposits. The image processing is applied using Landsat-7 satellite data to discriminate structure and lithology for defining the horizons of the radioactive anomalies of each rock unit. The extracted structural lineaments, using Ge Analyst-PCl package, from digital ETM data showed that the main structural trends are NE-SW and NW-SE normal faults which originated as extensional fractures with lateral dip-slip displacement. The axial trace of Gabal Ralal fold is curved and plunging to Wand SW directions while the northeastern part (Gabal Dalfa) is plunging to NE direction. The use of remote sensing data and ...
There are at present 116 floating production systems and 60 storage vessels dotting the oceans involved in hydrocarbon exploration and production activities. Although concentrated mostly in the North Sea, they can be found also off the coast of Australia, eastern Canada, Brazil, some African nations and the Gulf of Mexico. They range from converted tankers to purpose built rigs. The most adaptable of the various systems is the floating production, storage and offloading (FPSO) vessel, first developed as a cost-effective means of developing fields in Brazil's very deep offshore areas. Still being tested and modified for work in widely different environments, FPSOs appear to have met all requirements in producing expenditure efficiencies, maximizing profits, and protecting workers. One of the most efficient and most technically advanced is a 292-metre long FPSO built for the Terra Nova Alliance by Daewoo Shipyards in South Korea. It arrived at Newfoundland's Bull Arm ...
Hydrogen (H{sub 2}) emissions characteristics of H{sub 2}-diesel dual fuel engine were measured using a 2004 turbocharged heavy-duty diesel engine with H{sub 2} supplemented into the intake air. The emissions of H{sub 2} were measured using an Electron Pulse Ionization (EPI) Mass Spectrometer (MS). The effect of the amount of H{sub 2} added, the engine load, and diesel fuel flow rates on the emissions of H{sub 2} and its combustion efficiency in the engine were investigated. The addition of H{sub 2} under high load operation was notable for its ability to obtain high H{sub 2} combustion efficiency and improve brake thermal efficiency. However, the addition of H{sub 2} at low load resulted in high emissions of H{sub 2} due to the failure to initiate and support a sufficiently vigorous flame for the complete combustion of H{sub 2} present outside the diesel spray plume. The maximum H{sub 2} emissions of 1.4% (volume in dry exhaust gas) were observed with the addition of 6% H{sub 2} at ...
According to the LeChatelier-Braun principle, when a closed quiescent system initially in an equilibrium or unstressed steady state is subjected to an externally imposed ``stress'' it responds in a manner tending to alleviate that stress. Use of this entropically based qualitative rule, in combination with the notion of Maxwell thermal stresses existing in nonisothermal gases and liquids, enables one to (i) derive Maxwell's thermal-creep boundary condition prevailing at the boundary between a solid and a fluid (either gas or liquid) and (ii) rationalize the phenomenon of thermophoresis in liquids, for which, in contrast with the case of gases, an elementary explanation is currently lacking. These two objectives are achieved by quantitatively interpreting the heretofore qualitative LeChatelier-Braun notion of stress in the present context as being the fluid's stress tensor, the latter including Maxwell's thermal stress. In effect, thermophoretic particle motion is interpreted as the ...
Introduction The progressive growth of malignancies is accompanied by a decline in the immune response through mechanisms which are poorly understood. Apoptosis and induction of inflammation by tumor released cytokines as tumor escape mechanisms have been proposed to play an important role in colorectal carcinogenesis. Methods Expression of Tumor necrosis factor-alpha (TNF-?) was analyzed in colorectal cancer specimen and the cancer cell line HT-29 by immunohistochemistry and RT-PCR. TNF-? expression on protein and mRNA level were correlated with clinical characteristics and impact on survival. TNFR-1 was co-labelled with TNF-? and CD8+ cytotoxic T cells in immunofluorescence double staining experiments. Results: 94% (n?=?98/104) of the patients with CRC expressed TNF-?. High TNF-? express...
PurposeThe behavior of trigeminocardiac reflex (TCR) during maxillofacial surgeries has not yet been sufficiently studied and knowledge of its behavior is limited to some case reports. The present study aimed to assess the occurrence of TCR in bilateral sagittal split ramus osteotomy and to determine the possible effect of Gow-Gates block on its incidence. Materials and MethodsTwenty candidates for bilateral sagittal split ramus osteotomy (included were American Society of Anesthesiologists I Class III patients with a prognathism of 3 to 5 mm) were given routine general anesthesia after at least 12 hours of fasting. All patients received Gow-Gates mandibular nerve block on 1 random side (case ramus; the other side was used as the control) after induction of general anesthesia before surger...
In this article, a method of producing elastic ferromagnetic composite containing particles of chemical pure iron with sizes of 0.10-0.15 mm was described. The particles were dispersed in an elastic matrix of an elastic silicone rubber. The filling factor of composite by ferromagnetic particles and porous factors were changed in the range from 0.15 to 0.45. The samples of the obtained composite were placed in the magnetic field with induction of 0-8 T, produced by the Bitter-type magnet. The longitudinal magnetostriction of samples was measured by using a coaxial capacitor with a movable plate. It was found that the maximal relative elongation of samples was 4.81% and hysteresis of magnetostriction and also remanent magnetostriction amounted to 1.08%. A slow decay of remanent magnetostriction up to 0.14% in 10{sup 5} s was also observed.
The presence of washed or unwashed cellophane alone or together with a bleomycin, mitomycin C or hydrochlorothiazide, ('Esidrex') showed no appreciable effect on survival of either unirradiated or irradiated conidia. Irradiation for a period of 20min reduced the survival of conidia to 20%. The growth of irradiated conidia in the presence of bleomycin, mitomycin C or Esidrex is associated with a 2- to 3-fold increase in the frequency of gene convertants, but was not accompanied by an increase in point mutants. When conidia were grown on cellophane but otherwise treated as before the frequency of gene convertants was increased 8-fold, but induction of point mutants was negligible. This effect was the same for irradiated and unirradiated conidia. The environment created by the cellophane in contract with the medium appears to affect the action of each of the three compounds synergistically. (author).
Inductive electromagnetic launchers, or coilguns, use discrete solenoidal coils to accelerate a coaxial conductive armature. To date, Sandia has been using an internally developed code, SLINGSHOT, as a point-mass lumped circuit element simulation tool for modeling coilgun behavior for design and verification purposes. This code has shortcomings in terms of accurately modeling gun performance under stressful electromagnetic propulsion environments. To correct for these limitations, it was decided to attempt to closely couple two Sandia simulation codes, Xyce and ALEGRA, to develop a more rigorous simulation capability for demanding launch applications. This report summarizes the modifications made to each respective code and the path forward to completing interfacing between them.
An attempt is made to induce in mud crab (Scylla serrata) epileptiform activities that resemble the generalized epileptic seizures. Cerebral ganglion of crab was exposed in situ, to a convulsant drug pentylenetetrazole (PTZ) 100?mM, for induction of seizures. Also, crabs were pretreated with antiepileptic drug viz sodium valproate (120??mol/l) to inhibit epileptiform activities. The surface electrical discharges of cerebral ganglion were recorded using Unkelscope (MIT, USA) in control as well as experimental animals. The cerebral ganglion of crab showed a pattern of high cerebral electrical discharges after PTZ treatment compared to control. The sodium valproate promoted sedative action in control and prevented PTZ-mediated epileptiform discharges. Glutamate and GABA contents in cerebral g...
This paper presents a new method to improve sensorless performance of matrix converter drives using a parameter estimation scheme. To improve low-speed sensorless performance, the non-Iinearities of a matrix converter drive such as commutation delays, turn-on and turn-off times of switching devices, and on-state switching device voltage drop is modelled using PQR transformation and compensated using a reference current control scheme. To eliminate the input current distortion due to the input voltage unbalance, a simple method using PQR transformation is also presented. The proposed compensation method is applied for high performance induction motor drives using a 3 kW matrix converter system without a speed sensor. Experimental results are shown to illustrate the feasibility of the proposed strategy.
The spontaneous precipitation of calcium sulfate in supersaturated solutions over the temperature range between 25.0 and 80.0 C was investigated by monitoring the solution specific conductivity during desupersaturation. From measurements of the induction times preceding the onset of precipitation the surface energy of the forming solid, identified as gypsum, was found between ca. 12 and 25 mJ/m{sup 2} for the temperature range between 80.0 and 25.0 C, respectively. Kinetics analysis showed that over 50 C it is possible that anhydrous calcium sulfate is forming as a transient phase converting into the more stable calcium sulfate dihydrate. The linear dependence of the rates of precipitation on the relative solution supersaturation suggested a mechanism according to which the growth units are integrated into the active sites of the supercritical nuclei by surface diffusion. According to the morphological examination of the crystals it is possible that crystal growth ...
Lung cancer is still difficult to treat by current chemotherapeutic procedures. We recently found that MVL, an anti-HIV lectin from blue-green algae Microcystis viridis, also has antitumor activity. The objective of this study was to investigate apoptosis-inducing activity of recombinant MVL (R-MVL) and proteomic changes in A549 cells, and to identify the molecular pathways responsible for the anti-cancer action of R-MVL. We found that R-MVL induces A549 cells apoptosis in a dose-dependent manner by using MTT assay, fluorescent microscope (FM) and flow cytometry (FCM), and the IC50 was calculated to be 24.12??g/ml. Subsequently, 7 altered proteins in R-MVL-treated A549 cells were identified, including upregulated aldehyde dehydrogenase 1 and ?-actin, and five downregulated proteins: heat s...
Early failure of an induction-hardening carbon steel pipe, which was used to transport tailing slurry, was caused by pitting corrosion. The microstructure on the internal pipe surface layer was found being a mixture of martensite, pearlite and ferrite. In this work, the pitting corrosion behavior of each constitute in the microstructure of steel is investigated with electrochemical noise analyses; the electronic properties of passive films were studied with Mott-Schottky relationship. It is found that the passive films formed on the materials under investigation are highly disordered n-type semiconductors. The high-to-low pitting susceptibility is ferrite > martensite > pearlite. The pitting resistance is related to the semiconductive nature of the passive film formed on each constitute. The pitting susceptibility increases with the donor concentration in the passive films. (author)
Wild and tissue cultured plants of Portulaca grandiflora Hook. have shown to be able to decolorize a sulfonated diazo dye Navy Blue HE2R (NBHE2R) up to 98% in 40h. A significant induction in the activities of lignin peroxidase, tyrosinase and DCIP reductase was observed in the roots during dye decolorization. The wild plants and tissue cultures could independently decolorize and degrade NBHE2R into metabolites viz. N-benzylacetamide and 6-diazenyl-4-hydroxynaphthalene-2-sulfonic acid. A dye mixture and a textile effluent were also decolorized efficiently by P. grandiflora. The phytotoxicity study revealed reduction in the toxicity due to metabolites formed after dye degradation.
Each of the three cysteine residues in the Escherichia coli RecA protein was replaced with a number of other amino acids. To do this, each cysteine codon was first converted to a chain-terminating amber codon by oligonucleotide-directed mutagenesis. These amber mutants were then either assayed for function in different suppressor strains or reverted by a second round of mutagenesis with oligonucleotides that had random sequences at the amber codon. Thirty-three different amino acid substitutions were obtained. Mutants were tested for three functions of RecA: survival following UV irradiation, homologous recombination, and induction of the SOS response. It was found that although none of the cysteines is essential for activity, mutations at each of these positions can affect one or more of the activities of RecA, depending on the particular amino acid substitution. In addition, the cysteine at position 116 appears to be involved in the RecA-promoted cleavage of the ...
This article describes the complete microsporogenesis and pollen formation in cassava (Manihot esculenta Crantz) at the various developmental stages (pollen mother cell, meiosis, tetrads, early free spore, mid uninucleate, late uninucleate, binucleate and mature pollen grain). Light microscopy, transmission electron microscopy and confocal laser scanning microscopy were used for the study. Floral bud size and other inflorescence characteristics were correlated with specific stages of the microspore development. This association allows a rapid selection of floral buds with similar microspore developmental stages, useful when a large number of homogeneous cells are needed for analysis and for in vitro induction of androgenesis. This article also compares methods for digestion the exine wall ...
The results of following the oxidative degradation of a plastic-bonded explosive (PBX 9501) are reported. Into over 1100 sealed containers were placed samples of PBX 9501 and combinations of its components and aged at relatively low temperatures to induce oxidative degradation of the samples. One of the components of the explosive is a poly(ester urethane) polymer and the oxidative degradation of the samples were following by measuring the molecular weight change of the polymer by gel permeation chromatography (coupled with both differential refractive index and multiangle laser light scattering detectors). Multiple temperatures between 40 and 64 degreeC were used to accelerate the aging of the samples. Interesting induction period behavior, along with both molecular weight increasing (cro...
Ex vivo expanded peripheral blood progenitor cells (PBPC) have been shown to provide rapid neutrophil engraftment, and in some patients, to eliminate neutropenia after transplantation to support high-dose chemotherapy. However, the effect of expansion culture on stem cell content and potential loss of stem cells caused by induction of differentiation remains a concern. We have transplanted 21 patients with breast cancer with expanded autologous PBPC, with 11 patients receiving expanded PBPC as their sole hematopoietic cell source. In these studies, the CD34+ cells were selected and cultured for 10 days in defined media containing 100 ng/mL each of recombinant human stem cell factor (rhSCF), recombinant human granulocyte colony stimulating factor (rhG-CSF), and recombinant human megakaryocy...
The aim of this thesis is the design of a faults diagnosis-aiding system in a nuclear facility of the Cea. Actually the existing system allows the optimization of the production processes in regular operating conditions. Meanwhile during accidental events, the alarms, managed by threshold, are bringing no relevant information. To increase the reliability and the safety, the human operator needs a faults diagnosis-aiding system. The developed system, SECAPI, combines problem solving techniques and automatic learning techniques, that allow the diagnosis and the the simulation of various faults happening on nuclear facilities. Its reasoning principle uses case-based and rules-based techniques. SECAPI owns a learning module which reads out knowledge connected with faults. It can then simulate various faults, using the inductive logical computing. SECAPI has been applied on a radioactive tritium treatment operating channel, at the Cea with good results. (A.L.B.)
The feather has been widely used as a indicator tissue of metal exposure in birds. The feathers were collected from Tuskegee University poultry farm (TUPF) and Harrison Poultry farm (HPF) chicken and analyzed by Inductively Coupled Plasma Atomic Emission Spectroscopy for lead, cadmium, cobalt, chromium, and copper contaminations. The mean levels of lead, cadmium, cobalt, chromium, and copper in TUPF chicken were 3.67, 0.13, 12.23, 0.22, and 7.71 ppm, respectively, and in HPF chicken were 5.32, 0.096, 11.03, 0.15, and 8.06 ppm, respectively. The mean levels of these metals did not show any significant difference between TUPF and HPF chicken.
DNA methylation is considered as a potential cause of aberrations in regulation of gene expression during carcinogenesis. Therefore, changes in DNA methylation patterns may be targets for chemoprevention. In the present study, we investigated effects of all-trans retinoic acid (ATRA), vitamin D3, and resveratrol alone and in combination with adenosine analogues: 2-chloro-2'-deoxyadenosine (2CdA) and 9-beta-d-arabinosyl-2-fluoroadenine (F-ara-A), on methylation and expression of retinoic acid receptor beta 2 (RARbeta2) in MCF-7 and MDA-MB-231 breast cancer cell lines. Alterations in methylation and expression levels after treatment of cells with the tested compounds were evaluated by methylation-sensitive restriction analysis (MSRA) and real-time PCR, respectively. RARbeta2 promoter in the ...
The author explains current developments in high voltage cable technology and subsequently describes problems inherent in its application, from the users viewpoint, in municipal electricity supply. The planning of a high voltage cable network and the selection of a specific type of cable are not only dependent on the typical properties of various cables but to a major degree also on the feasible laying technique, the power transmitted, the costs, the stellation treatment of the high voltage network, the acceptance requirement, the inductive influence from telecommunication cable, thermal influences from the environment, eventual safeguards from mechanical and chemical damage to the network, frequency of failure and surveillance and breakdown location. In conclusion, the author portrays potential developments in the fields of high and maximum voltage cable from the perspectives of today.
This study was conducted to investigate the antibacterial effect of BSAP-254 on Bacillus cereus with the induced stress proteins. The BSAP-254 is an antimicrobial peptide isolated from soybean-fermenting bacteria, Bacillus subtilis SC-8. It had a narrow spectrum of activity against B. cereus group. The growth inhibitory effect of BSAP-254 (50??g/mL) reduced the population of B. cereus from >108 to 104 colony-forming units per milliliter within 30?min. In B. cereus exposed to BSAP-254, 14 intracellular proteins were differentially expressed as determined by 2-DE coupled with MS. Of the differentially expressed proteins identified, the stress protein GroEL, which is heat shock protein, was induced in B. cereus exposed to antibacterial peptide.
Field-annealed Co-based amorphous ribbon (Metglas? 2705M) with a meander structure is fabricated by MEMS technology and the giant magnetoimpedance (GMI) effects are studied at different magnetic fields and frequencies. The maximum longitudinal GMI ratio of the ribbon is 193.7% and the magnetic field sensitivity is 17.4%/Oe. The maximum GMI ratio of the meander ribbon is much larger than the single strip ribbon mainly due to the larger change ratio of inductance L. The sensitivity of an output U reach up to 10 V/A and U thermal fluctuation is less than 15 mV in the temperature range of ?20 to 40?C. This meander shape ribbon can be considered as a good candidate for the GMI-based sensor fabrication.
Human embryonic stem (ES) cells can undergo spontaneously differentiation in standard culture conditions, demonstrating that the undifferentiated state is relatively unstable. The heterogeneous expression of SSEA3 observed within human ES colonies, provides a means to examine undifferentiated stem cell substates. Through functional testing of single cells we have shown that undifferentiated ES cells can be segregated into functionally discrete subpopulations on the basis of SSEA3 expression: SSEA3(High), SSEA(Low) and SSEA3(Negative). Human ES subpopulations were found to be interconvertible, but they possess distinct properties when challenged to differentiate along the neural lineage. These data suggest that ES cells with pluripotent/self-renewal capacities can exhibit different responses to induction of differentiation. PMID:21763622
Objective: : Evaluate expression of inducible negative regulators of JAK/STAT pathway and their target proteins during the course of ligature-induced experimental periodontal disease in rats. Design: : Rats were sacrificed 07, 15 and 30days after disease induction for histological evaluation of periodontal inflammation and macroscopic analysis of alveolar bone loss. SOCS expression and the activation status of STAT1 and STAT3 were evaluated in gingival biopsies by real time PCR and Western blot. Results: : Ligature-induced model presented significant progressive bone loss from 7 to 30days. Inflammation was evident and similar for 07 and 15days; however, a decrease on severity at the end of the experimental period was observed. There was a significant (p<0.05) increase on SOCS1 and SOCS3 ge...
AbstractBackground: So far, infliximab (IFX) therapy for the treatment of Crohn's disease (CD) has generally been guided by clinical symptoms. Data on treatment response as ascertained by endoscopy in IFX therapy are scarce. The aims of this study were to measure the endoscopic response rate during IFX induction and maintenance therapy in luminal CD, and also evaluate the role of endoscopy in monitoring IFX therapy. Methods: Data obtained from 71 patients with active luminal CD and treated with IFX were analyzed retrospectively. The endoscopy findings were scored according to mucosal activity as: 0 (remission), 1-2 (mild), 3-4 (moderate), and 5-6 (severe). A positive endoscopic response was determined by a decrease in score of at least two points and mucosal healing was assigned a score of...
The present study was designed to determine the exercise intensity equivalent to the metabolic aerobic/anaerobic transition of alloxan diabetic rats, through lactate minimum test (LMT), and to evaluate the effects of swimming exercise at this intensity (LM) on the glucose and protein metabolism of these animals. Adult male Wistar rats received alloxan (SD, alloxan-injected rats that remained sedentary) intravenously (30 mg kg?1 body weight) for diabetes induction. As controls (SC, vehicle-injected rats that remained sedentary), vehicle-injected rats were utilized. Two weeks later, the animals were submitted to oral glucose tolerance test (oGTT) and LMT. After the tests, some of the animals were submitted to swimming exercise training [TC (vehicle-injected rats that performed a 6-week exerc...
The presence of washed or unwashed cellophane alone or together with a bleomycin, mitomycin C or hydrochlorothiazide, ('Esidrex') showed no appreciable effect on survival of either unirradiated or irradiated conidia. Irradiation for a period of 20min reduced the survival of conidia to 20%. The growth of irradiated conidia in the presence of bleomycin, mitomycin C or Esidrex is associated with a 2- to 3-fold increase in the frequency of gene convertants, but was not accompanied by an increase in point mutants. When conidia were grown on cellophane but otherwise treated as before the frequency of gene convertants was increased 8-fold, but induction of point mutants was negligible. This effect was the same for irradiated and unirradiated conidia. The environment created by the cellophane in contract with the medium appears to affect the action of each of the three compounds synergistically.
The paper describes novel analytical methods developed for the detection of previous neutron irradiation and reprocessing of illicit nuclear materials, which is an important characteristic of nuclear materials of unknown origin in nuclear forensics. Alpha spectrometry and inductively coupled plasma sector-field mass spectrometry (ICP-SFMS) using solution nebulization and direct, quasi-non-destructive laser ablation as sample introduction were applied for the measurement of trace-level "2"3"2U, "2"3"6U and plutonium isotopes deriving from previous neutron irradiation of uranium-containing nuclear materials. The measured radionuclides and isotope ratios give important information on the raw material used for fuel production and enable confirm the supposed provenance of illicit nuclear material.
Coilguns have the ability to provide magnetic pressure to projectiles which results in near constant acceleration. However, to achieve this performance and control projectile hearing, significant constraints are placed on the design of the coils. We are developing coils to produce an effective projectile base pressure of 100 MPa (1kbar) as a step toward reaching base pressures of 200 MPa. The design uses a scalable technology applicable to the entire range of breech to muzzle coils of a multi-stage launcher. This paper presents the design of capacitor-driven coils for launching nominal 50 mm, 350 gram projectiles. Design criteria, constraints, mechanical stress analysis, launcher performance, and test results are discussed.
Pro-inflammatory cytokines may directly influence the viability and metabolic function of colonic epithelial cells (CEC) as an early event in the development of inflammatory bowel disease. We report here that TNF-alpha+IFN-gamma induced a synergistic, concentration-dependent decline in butyrate oxidation, an essential energy supply, in HT-29 and DLD-1 cells. TNF-alpha+IFN-gamma induced a parallel profound decline in cell viability in HT-29 cells, but not in DLD-1 cells, where impairment of butyrate oxidation seemed to precede later occurrence of cell damage. TNF-alpha+INF-gamma induced CEC damage was independent on NO formation and involved the IFN-gamma signalling pathway as well as induction of apoptosis. If cytokines have similar effects in vivo, these may lead to energy deficiency and thus contribute to CEC damage and disturbance of the epithelial integrity.
Objective Over recent years the Internet has become an increasingly popular source of support and information for infertility, with a growing number of online support groups now available to individuals affected by fertility problems. The aims of the present study were therefore to explore the online experiences of individuals accessing infertility support groups via the Internet. Methods Ninety-five participants who were recruited from several online infertility support groups completed an online questionnaire containing a series of open-ended questions. Responses to the open-ended questions were analysed using inductive thematic analysis. Results The thematic analysis revealed five recurrent themes, which were labelled: `unique features of online social support', `improved relationship w...
SBA-15 supported nano-scaled copper oxide was synthesized by impregnation method via ultrasonic-assisted route. The removal test from gas mixture containing 0.1?vol.% hydrogen sulfide was carried out over this material at atmospheric conditions. The effects of the chemical nature of copper oxide and the textural properties of the material on removal capacity were studied. The materials before and after the removal test were analyzed by nitrogen adsorption, X-ray diffraction, Transmission Electron Microscope, X-ray photoelectron Spectroscopy, Fourier Transform Infrared Spectrometer and Inductive Coupled Plasma. The results showed that copper species are located predominantly in mesopore channels, existing as copper oxide nanoparticles. Mesopores are active sites for removal reaction. The ou...
Electromagnetic forming (EMF) is a forming process that relies on the inductive electromagnetic force to deform metallic workpiece at high speed. Calculation of the electromagnetic force is essential to understand the EMF process. However, accurate calculation requires complex numerical solution, in which the coupling between the electromagnetic process and the deformation of workpiece needs be considered. In this paper, an appropriate formula has been developed to calculate the electromagnetic force in metal work-piece in the sheet EMF process. The effects of the geometric size of coil, the material properties, and the parameters of discharge circuit on electromagnetic force are taken into consideration. Through the formula, the electromagnetic force at different time and in different positions of the workpiece can be predicted. The calculated electromagnetic force and magnetic field are in good agreement with the numerical and experimental results. The accurate ...
Abstract Epstein-Barr virus (EBV), which infects not only B cells, but also T cells and natural killer (NK) cells, is associated with multiple lymphoid malignancies. Recently, the proteasome inhibitor bortezomib was reported to induce apoptosis of EBV-transformed B cells. We evaluated the killing effect of this proteasome inhibitor on EBV-associated T lymphoma cells and NK lymphoma cells. First, we found that bortezomib treatment decreased the viability of multiple T and NK cell lines. No significant difference was observed between EBV-positive and EBV-negative cell lines. The decreased viability in response to bortezomib treatment was abrogated by a pan-caspase inhibitor. The induction of apoptosis was confirmed by flow cytometric assessment of annexin V staining. Additionally, cleavage o...
Using a case-study, inductive, narrative approach, this article explores the history, drivers, benefits, and barriers to the Bakun Hydroelectric Project in East Malaysia. Situated on the island of Borneo, Bakun Dam is a 204m high concrete face, rock filled dam on the Balui River in the Upper Rajang Basin in the rainforests of Sarawak. Bakun Dam and its affiliated infrastructure could be the single largest and most expensive energy project ever undertaken in Southeast Asia. Based on data collected through site visits, original field research in Sarawak, and more than 80 research interviews, the article begins by teasing out the complex history and drivers behind the Bakun project before identifying a set of potential social, political, and economic benefits the project could deliver. It the...
Recently, the precise isotope ratios of some refractory elements in meteorites have been reported using inductively coupled plasma mass spectrometry. The in situ decay of {sup 182}Hf (T{sub 1/2}=9 Myr), which was produced at the latest nucleosynthesis, is recognized in many meteorites as isotopic anomalies of its daughter isotope, {sup 182}W. The degrees of relative {sup 182}W isotopic deviation in extra-terrestrial and terrestrial silicate samples vary from +0.3% to {+-}0% related to the size of their parent bodies. One ready interpretation of its correlation is the difference in timing of metal-silicate separation in the parent bodies. Between the earth and meteorite parent bodies, the difference is calculated to be about four times of the half-life of {sup 182}Hf, equivalent to 36 Myr. (author)
Summary Background- Treatments that achieve sustainable steroid-free clinical remission in Crohn-s disease are needed; however, long-term steroid-sparing efficacy data are limited. Aim- To evaluate steroid-sparing efficacy and the impact of steroid discontinuation on adverse events during treatment of Crohn's disease with adalimumab in the phase III randomised, double-blind 1-year CHARM trial and for an additional 2-years in its open-label extension ADHERE. Methods- Steroid-free remission and response and steroid-sparing (-50% steroid dose reduction) remission rates were evaluated over 3-years in patients who were taking corticosteroids at CHARM baseline. Results- Of 778 patients randomised in CHARM (including those who did not achieve clinical response to open-label induction therapy), 31...
The free-electron laser (FEL) projects that are currently in progress in Japan are discussed. Particular attention is given to the storage ring FELs at the Electrotechnical Laboratory, the Institute for Molecular Physics, and the Kyushu University; the superconducting linear accelerator (SC linac) FELs being developed at the Japan Atomic Energy Research Institute; and the RF-linac FEL being developed by the Nuclear Engineering Research Laboratory of the University of Tokyo, the Institute of Scientific and Industrial Research of Osaka University, the Mitsubishi Electric Company, and Tokyo Institute of Technology. Consideration is also given to the microtron FEL being constructed at the Nihon University; the induction-linac and pulseline FELs of the Institute of Laser Engineering of Osaka University, the Institute of Physical and Chemical Research, the National Laboratory for High-Energy Physics, and ISAS; and the Smith-Purcell-effect FEL developed by Tohoku ...
Glycyrrhiza glabra root is one of the common traditional Chinese medicines and used as flavoring and sweetening agents for tobaccos, chewing gums, candies, toothpaste and beverages. While glycyrrhizin is one of the main components in the extract of G. glabra root and has been characterized, the other components have not been well characterized. The mechanism of growth activation of breast cancer MCF-7 cells, including the activation of Erk1/2 and Akt, and the transcriptional regulation of estrogen-responsive genes, was examined by means of sulforhodamine B, luciferase reporter gene, real-time RT-PCR and Western blotting assays after the induction of the cells with the extract of G. glabra root. The extract has similar activity to that induced by 17b-estradiol (E2), although glycyrrhizin di...
This paper presents a new method to compensate the nonlinearities for matrix converter drives. The nonlinearities of matrix converter drives such as commutation delay, turn-on and turn-off time of the switching devices, and on-state switching device voltage drop is corrected by a new matrix converter model using the direction of current. The proposed method does not need any additional hardware or complicated software and it is easy to realize by applying the algorithm to the conventional vector control. The proposed compensation method is applied for high-performance induction motor drives using a 3-kW matrix converter system without a speed sensor. Experimental results show the proposed method provides good compensating characteristics.