WorldWideScience
1

[Pulmonary vascular manifestations in hereditary hemorrhagic telangiectasia].  

Science.gov (United States)

Hereditary hemorrhagic telangiectasia (Osler-Rendu-Weber disease) is a genetic disorder with autosomal dominance, variable penetrance, and an estimated prevalence of 1/10,000 inhabitants in France. Diagnosis is based on clinical criteria including epistaxis, telangiectasia, visceral manifestations, and familial occurrence. Pulmonary arteriovenous malformations, present in 15-33% of patients, are its primary visceral complications. The disease may be revealed by infectious and ischemic neurological manifestations due to paradoxical embolism. The high frequency of neurologic complications even in asymptomatic patients justifies systematic screening for pulmonary arteriovenous malformations. Treatment of these malformations is based on percutaneous transcatheter coil embolization of the feeding artery. Pulmonary arterial hypertension is rare in this disease. It may be due to systemic arteriovenous shunting ...

2005-11-01

2

Vitamins C and E to Prevent Complications of Pregnancy-Associated Hypertension  

UK PubMed Central (United Kingdom)

BackgroundOxidative stress has been proposed as a mechanism linking the poor placental perfusion characteristic of preeclampsia with the clinical manifestations of...Full Text Available

2010-04-08

3

Validation of Cultivation and PCR Methods for Diagnosis of Lyme Neuroborreliosis?  

UK PubMed Central (United Kingdom)

Borrelial infection may manifest with a wide range of clinical signs, and in many cases, microbiological findings are essential for a proper diagnosis. This study included 48 patients with a working...Full Text Available

2008-10-01

4

Infection dynamics and clinical manifestations following experimental inoculation of gilts at 90 days of gestation with a low dose of porcine reproductive and respiratory syndrome virus  

UK PubMed Central (United Kingdom)

Understanding the dynamics of porcine reproductive and respiratory syndrome virus (PRRSV) vertical transmission is important to enhance the accuracy of monitoring protocols for endemically infected...Full Text Available

2009-10-01

5

Health-Related Quality of Life Among Long-Term Rectal Cancer Survivors With an Ostomy: Manifestations by Sex  

UK PubMed Central (United Kingdom)

PurposeIntestinal stomas can pose significant challenges for long-term (≥ 5 years) rectal cancer (RC) survivors. Specifying common challenges and sociodemographic or clinical...Full Text Available

2009-10-01

6

Genetic and cellular evidence of vascular inflammation in neurofibromin-deficient mice and humans  

UK PubMed Central (United Kingdom)

Neurofibromatosis type 1 (NF1) results from mutations in the NF1 tumor suppressor gene, which encodes the protein neurofibromin. NF1 patients display diverse clinical manifestations,...Full Text Available

2010-03-01

7

Clinical perspective on aztreonam lysine for inhalation in patients with cystic fibrosis  

UK PubMed Central (United Kingdom)

Progressive obstructive lung disease is a characteristic component of cystic fibrosis (CF). It is the pulmonary manifestations, including obstruction and endobronchial infection, which directly contribute...Full Text Available

8

Adverse reactions triggered by dental local anesthetics: a clinical survey.  

UK PubMed Central (United Kingdom)

One hundred and seventy-nine patients completed a questionnaire focusing on adverse reactions to dental local anesthetics as manifested by 16 signs and symptoms. Twenty-six percent of the participants...Full Text Available

2000-01-01

9

Comparative optimism in models involving both classical clinical and gene expression information  

UK PubMed Central (United Kingdom)

BackgroundIn cancer research, most clinical variables have already been investigated and are now well established. The use of transcriptomic variables has raised two problems: restricting...Full Text Available

10

Glossitis of Military Workingn> Dogs in South Vietnam: History and Clinical Characteristics.  

Science.gov (United States)

Glossitis among U.S. military working dogs in South Vietnam was characterized by variable redness and loss of papillae on the anterodorsal third of the tongue; salivation, drooling, and inappetence were the principal clinical signs. Symptomatic treatment ...

1973-01-01

11

Positive IgG Western Blot for Borrelia burgdorferi in Colombia  

Scientific Electronic Library Online (English)

Abstract in english In order to evaluate the presence of specific IgG antibodies to Borrelia burgdorferi in patients with clinical manifestations associated with Lyme borreliosis in Cali, Colombia, 20 serum samples from patients with dermatologic signs, one cerebrospinal fluid (CSF) sample from a patient with chronic neurologic and arthritic manifestations, and twelve serum samples from individuals without clinical signs associated with Lyme borreliosis were analyzed by IgG Western blot. The (more) results were interpreted following the recommendations of the Centers for Diseases Control and Prevention (CDC) for IgG Western blots. Four samples fulfilled the CDC criteria: two serum specimens from patients with morphea (localized scleroderma), the CSF from the patient with neurologic and arthritic manifestations, and one of the controls. Interpretation of positive serology for Lyme ...

1999-07-01

12

Soft tissue manifestations of early rheumatic disease. Imaging with MRI  

International Nuclear Information System (INIS)

The aim of this study was to evaluate typical magnetic resonance imaging (MRI) findings in early rheumatic diseases manifesting at the soft tissues of the hand using a retrospective analysis. A total of 186 MRI examinations of patients with clinical suspicion of a rheumatic disease were evaluated in a consensus reading by two experienced radiologists. All imaging patterns were assessed with respect to their type and localization. Under blinded and non-blinded conditions diagnoses were correlated with final clinical diagnosis. The most frequent diagnoses were rheumatoid arthritis (RA, 45.7%) and psoriatic arthritis (PsA, 15.6%). The mean correlation between clinical and MRI diagnosis (r) was 0.75 in blinded and 0.853 in non-blinded reading (p <0.001). The following extra-articular imaging patterns were found: synovitis (59.1%), tendovaginitis (91.4%), dactylitis (14.5%), and bone marrow edema (18.3%). ...

2006-08-01

13

[Heart injuries: diagnosis and therapy].  

Science.gov (United States)

The clinical manifestation of wounds of the heart is determined by the mode, site and size of the injury as well as the structure of the pericardial and myocardial lesion. Diagnosis can be confirmed by ECG and echocardiography. Only 20% of the patients with penetrating wounds of the heart live for more than 30 minutes. Pericardio-centesis should be used only to gain time for a safe sternotomy, cardiac decompression and suture of the wound of the heart. An aggressive surgical approach is mandatory. Cardiopulmonary bypass is necessary only to correct of concomitant lesions. PMID:1983618

1990-01-01

14

Glossitis of military workingn> dogs in south Vietnam; histopathologic observations.  

Science.gov (United States)

Glossitis, known clinically as "redtongue," was studied in tissues from 34 military working dogs (MWD) in the Republic of Vietnam. This condition was manifested grossly by loss of lingual papillae on the dorsal margins of the rostral third of the tongue. Microscopically, the principal lesions consisted of loss of filiform papillae, hemorrhage and edema in the lamina propria, acanthosis, and cellular infiltration. The cause of glossitis remains unknown at this time. PMID:1137213

1975-05-01

15

Evaluation of peripheral vascular disease by intravenous digital subtraction angiography with the Fuji computed radiography (FCR) system  

Energy Technology Data Exchange (ETDEWEB)

Intravenous digital subtraction angiography using Fuji computed radiography system (FCR-DSA) was used to evaluate 57 preoperative patients with clinical manifestations of peripheral vascular disease of lower extremity. With its high contrast resolution and good special resolution, image of FCR-DSA could offer optimal information of vascular abnormality in lower extremity distal to midfoot for the diagnosis and the choice of management.

1987-03-01

16

Evaluation of peripheral vascular disease by intravenous digital subtraction angiography with the Fuji computed radiography (FCR) system  

International Nuclear Information System (INIS)

Intravenous digital subtraction angiography using Fuji computed radiography system (FCR-DSA) was used to evaluate 57 preoperative patients with clinical manifestations of peripheral vascular disease of lower extremity. With its high contrast resolution and good special resolution, image of FCR-DSA could offer optimal information of vascular abnormality in lower extremity distal to midfoot for the diagnosis and the choice of management. (orig.).

1987-01-01

17

Radiation-induced large intracranial vessel occlusive vasculopathy.  

Science.gov (United States)

Two patients who developed large intracranial vessel occlusion after standard radiation therapy for brain tumor are described. This form of vascular occlusion is usually seen in patients who have previously been treated by radiotherapy for intracranial tumor who then develop a relatively acute change in neurologic status. Histology of the lesion mimics accelerated focal arteriosclerosis. The clinical and radiographic manifestations of one case were highly atypical. The vasculopathy became evident shortly after termination of radiation therapy for a fourth ventricular ependymoma, and the angiographic picture stimulated a diffuse arteritis. The second patient was more typical, with clinical symptoms developing 12 years after radiation therapy for an oligodendroglioma. Occlusion of a proximal vessel that had been included in the radiation port was demonstrated radiographically and confirmed by pathologic examination. The ...

1980-01-01

18

Radiation-induced large intracranial vessel occlusive vasculopathy  

Energy Technology Data Exchange (ETDEWEB)

Two patients who developed large intracranial vessel occlusion after standard radiation therapy for brain tumor are described. This form of vascular occlusion is usually seen in patients who have previously been treated by radiotherapy for intracranial tumor who then develop a relatively acute change in neurologic status. Histology of the lesion mimics accelerated focal arteriosclerosis. The clinical and radiographic manifestations of one case were highly atypical. The vasculopathy became evident shortly after termination of radiation therapy for a fourth ventricular ependymoma, and the angiographic picture stimulated a diffuse arteritis. The second patient was more typical, with clinical symptoms developing 12 years after radiation therapy for an oligodendroglioma. Occlusion of a proximal vessel that had been included in the radiation port was demonstrated radiographically and confirmed by pathologic examination. The ...

1980-01-01

19

Evaluation of an ELISA for the diagnosis of brucellosis.  

Science.gov (United States)

Brucela serology using ELISA and standard agglutination test was performed on 23 patients with prolonged fever where the test was requested, on 26 randomly chosen patients with prolonged fever where it was not requested and on 17 controls. ELISA was positive in 39.1, 26.9 and 0 per cent respectively in these groups. Brucellosis may often be unsuspected because of its varied clinical manifestations and may be a more important cause of fever than previously considered. Our data reaffirm that ELISA is superior to the standard agglutination test for the diagnosis of brucellosis. PMID:8707374

1996-06-01

20

Molecular Variability of Pseudallescheria boydii, a Neurotropic Opportunist  

UK PubMed Central (United Kingdom)

The sequences of the internal transcribed spacer (ITS) ribosomal DNA (rDNA) domain data obtained by restriction fragment length polymorphism analysis with 18S rDNA and fingerprinting (M13) for clinical...Full Text Available

2000-09-01

21

Lymphoma depletion during CD20 immunotherapy in mice is mediated by macrophage Fc?RI, Fc?RIII, and Fc?RIV  

UK PubMed Central (United Kingdom)

Despite the demonstrated clinical efficacy of CD20 monoclonal antibody (mAb) for lymphoma therapy, the in vivo mechanisms of tumor depletion remain controversial and variable. To identify the molecular...Full Text Available

2008-08-15

22

Cangrelor increases the magnitude of platelet inhibition and reduces interindividual variability in clopidogrel-pretreated subjects  

UK PubMed Central (United Kingdom)

BackgroundInadequate platelet inhibition despite aspirin and clopidogrel therapy during and after a percutaneous coronary intervention is associated with an impaired clinical outcome....Full Text Available

2009-05-01

23

Primary cutaneous Ewing's sarcoma/primitive neuroectodermal tumor manifesting numerous small and huge ulcerated masses: its complete remission by chemotherapy and magnetic resonance imaging findings  

International Nuclear Information System (INIS)

Extraskeletal Ewing's sarcoma (ES) and primitive neuroectodermal tumor (PNET) are widely regarded as clinically and histologically identical tumors which consist of small blue round cells. Extraskeletal ESs/PNETs usually occur in the deep soft tissues of the paraspinal region, chest wall, or lower extremities. However, superficially located cases, so-called cutaneous ESs/PNETs, are exceedingly rare, and the vast majority of the reported cases present as a single small mass. We present magnetic resonance imaging (MRI) findings and clinical course of a unique case of primary cutaneous ES/PNET presenting as numerous huge masses with severe ulceration on them. (orig.)

2010-06-01

24

Evaluation of therapeutic results in Ewing's sarcoma  

International Nuclear Information System (INIS)

The philosophy pervading the treatment approach to Ewing's sarcoma was to have therapy encompass all foci of disease, including sites of occult or potential involvement in addition to obvious clinical manifestations. The experience with integrated methods of treatment in 66 consecutive patients at the National Cancer Institute is reviewed. A median survival of 18 months (44 percent 2 year survival rate) for patients with recognizable metastases on admission bears impressive witness to the value of adjuvant therapy in Ewing's sarcoma. Even more encouraging, an uncorrected 5 year survival rate of 53 percent (42 percent continuously free of disease) for patients given ''pyrophylactic'', adjuvant therapy indicates the potential for permanent control of disease in a significant fraction of cases with clinically localized primary tumors. (U.S.).

25

The uterine blush. A potential false-positive in Meckel's scan interpretation  

Energy Technology Data Exchange (ETDEWEB)

To determine the presence, prevalence, and clinical importance of /sup 99m/Tc pertechnetate uterine uptake, this retrospective analysis of 71 Meckel's scans was undertaken. Specifically, each study was evaluated for the presence of a focal accumulation of radiotracer cephalad to the bladder. Patients received an intravenous dose of 150 microCi/kg of /sup 99m/Tc pertechnetate. Each study consisted of 15 one minute anterior serial gamma camera images, and a 15, 30, and 60 minute anterior, right lateral and posterior scintiscan. Menstrual histories were obtained from all patients except two. No males (33/33), nor premenstrual (13/13), menopausal (4/4) or posthysterectomy (2/2) patients revealed a uterine blush. Eleven of 15 patients (73%) with regular menses demonstrated a uterine blush. They were in the menstrual or secretory phases of their cycle. Four demonstrated no uterine uptake, had regular periods, but were in the proliferative phase of their cycle. ...

1982-10-01

26

On 15-component theory of a charged spin-1 particle with polarizability in Coulomb and Dirac monopole fields  

CERN Document Server

The problem of a spin 1 charged particle with electromagnetic polarizability, obeying a generalized 15-component quantum mechanical equation, is investigated in presence of the external Coulomb potential. With the use of the Wigner's functions techniques, separation of variables in the spherical tetrad basis is done and the 15-component radial system is given. It is shown that there exists a class of quantum states for which the additional characteristics, polarizability, does not manifest itself anyhow; at this the energy spectrum of the system coincides with the known spectrum of the scalar particle. For j=0 states, a 2-order differential equation is derived, it contains an additional potential term 1/r^{4}. In analogous approach wave functions the generalized particle are examined in presence of external Dirac monopole field. It is shown that there exists one special state with minimal conserved quantum number j_{min}. It this solution, ...

2006-01-01

27

Torsion sur rate baladeuse chez l?enfant: ? propos d?un cas  

British Library Electronic Table of Contents (United Kingdom)

R?sum? La rate baladeuse est une anomalie rare chez l?enfant. Elle est souvent d?crite chez l?adulte, particuli?rement la femme enceinte. Elle est due ? un d?faut de fixit? anatomique de la rate avec les organes de voisinage. Ses manifestations cliniques sont variables, mais la complication la plus redoutable est la survenue d?une torsion du p?dicule spl?nique. Nous rapportons le cas d?une fille de 11 ans qui s?est pr?sent?e avec des douleurs abdominales aigu?s et des vomissements. Les examens radiologiques ont montr? une absence de la vascularisation spl?nique. ? l?exploration chirurgicale, on a d?couvert une torsion du p?dicule spl?nique avec une isch?mie tissulaire avanc?e. La rate ?tait d?pourvue d?attaches ligamentaires. La d?torsion n?a pas permis de sauvegarder la rate, et une spl?n...

2009-01-01

28

Intracranial tuberculoma: MR imaging  

International Nuclear Information System (INIS)

MR studies of 6 patients with intracranial tuberculoma are reviewed. All patients also underwent CT scans which showed hypo- or isodense lesions with abnormal enhancement following contrast administration. MR showed lesions with prolongation of the T1 relaxation time in every case. On the T2-weighted sequences, the signal properties of the tuberculoma varied according to the stage of evolution of the lesion. Incipient tuberculomas appeared as scattered areas of hypointensity surrounded by edema. Mature tuberculomas were composed of a dark necrotic center surrounded by an isointense capsule which was, in turn, surrounded by edema. In one patient, the center of the lesion was hyperintense probably because of liquefaction and pus formation (tuberculous abscess). While both, CT and MR, were equally sensitive in visualizing the intracranial tuberculoma in every patient, MR was slightly superior in demonstrating the extent of the lesion, especially for brainstem tuberculomas. Nevertheless, ...

1988-11-01

29

Incidental brain lesions on MRI in the depressive elderly  

Energy Technology Data Exchange (ETDEWEB)

The study was designed to determine the correlation between parenchymal lesions on MRI and depression. Thirty patients with depression satisfying the following criteria were selected: (1) 60 years or over at the time of MRI scanning, (2) no evidence of cerebrovascular disorder or dementia, and (3) no evidence of neurological findings such as extremity palsy. Seventy six patients with no history of psychiatric visits to a clinic served as controls. There was no significant difference in risk factors for cerebrovascular disorders, such as hypertension, diabetes mellitus, and ischemic heart disease, between the depressive group and the control group. MRI manifestations were semiquantitatively scored according to the periventricular hyperintensity (PVH), white matter hyperintensity (WMH), and pons hyperintensity (PH). All of the PVH score, WMH score, and cerebral enlargement index correlated with age. Although there was no significant difference in ...

1994-07-01

30

Complications of gallstone disease: Mirizzi syndrome, cholecystocholedochal fistula, and gallstone ileus.  

Science.gov (United States)

Gallstone is a common disease with a 10% prevalence in the United States and Western Europe. However, it is only symptomatic in 20-30% of patients, with biliary pain "colic" being the most common symptom. Complications of asymptomatic gallstone disease are generally rare, with an incidence of <1 %/yr. The most common complications of gallstone disease are acute cholecystitis, acute pancreatitis, ascending cholangitis, and gangrenous gallbladder. Less frequent complications include Mirizzi syndrome, cholecystocholedochal fistula, and gallstone ileus. Mirizzi syndrome and cholecystocholedochal fistula are two manifestations of the same process that starts with impaction of a gallstone in the gallbladder neck that results in obstruction of the bile duct, causing jaundice. The gallstone may erode into the bile duct, causing cholecystocholedochal fistula. Gallstone ileus refers to small bowel obstruction resulting from the impaction of one or more gallstones after ...

2002-02-01

31

Reduction of fluoroscopic exposure for the air-contrast barium enema  

Energy Technology Data Exchange (ETDEWEB)

In a fluoroscopic imaging system, image quality and patient dose are both affected by the optical system linking the image intensifier with the video camera. The effect on patient exposure of increasing the optical iris aperture size over that required for other procedures performed on the same imaging system was investigated for the air-contrast barium enema examination. Using a large-area transmission ionisation chamber to monitor the Roentgen-area-product of entrance exposure, a decrease in fluoroscopic radiation of greater than 50% was clinically documented for a fluoroscopic system utilising kVp and mA variable automatic brightness control. For this iris change, the video image was of acceptable quality for positioning and monitoring the patient, and no deleterious effect was detected in the conduct of the air-contrast exam. The availability of a variable-sized operator-selectable iris diaphragm would permit this ...

1983-11-01

32

Soft tissue manifestations of early rheumatic disease. Imaging with MRI; Fruehmanifestationen rheumatischer Gelenkerkrankungen an den Weichgewebestrukturen der Hand. Nachweis mit der MRT  

Energy Technology Data Exchange (ETDEWEB)

The aim of this study was to evaluate typical magnetic resonance imaging (MRI) findings in early rheumatic diseases manifesting at the soft tissues of the hand using a retrospective analysis. A total of 186 MRI examinations of patients with clinical suspicion of a rheumatic disease were evaluated in a consensus reading by two experienced radiologists. All imaging patterns were assessed with respect to their type and localization. Under blinded and non-blinded conditions diagnoses were correlated with final clinical diagnosis. The most frequent diagnoses were rheumatoid arthritis (RA, 45.7%) and psoriatic arthritis (PsA, 15.6%). The mean correlation between clinical and MRI diagnosis (r) was 0.75 in blinded and 0.853 in non-blinded reading (p <0.001). The following extra-articular imaging patterns were found: synovitis (59.1%), tendovaginitis (91.4%), dactylitis (14.5%), and bone marrow edema ...

2006-08-15

33

Use of antivascular endothelial growth factor for diabetic macular edema  

UK PubMed Central (United Kingdom)

BackgroundDiabetic macular edema (DME) is one of the manifestations of diabetic retinopathy leading to loss of central vision and visual acuity. It manifests itself with swelling...Full Text Available

2010-01-01

34

Ocular manifestations of branchio-oculo-facial syndrome: Report of a novel mutation and review of the literature  

UK PubMed Central (United Kingdom)

PurposeTo report unusual ocular manifestations of branchio-oculo-facial syndrome (BOFS) caused by a novel mutation in activating enhancer binding protein 2 alpha (TFAP2A).MethodsFull...Full Text Available

35

Optical diagnostics based on elastic scattering: Recent clinical demonstrations with the Los Alamos Optical Biopsy System  

Energy Technology Data Exchange (ETDEWEB)

A non-invasive diagnostic tool that could identify malignancy in situ and in real time would have a major impact on the detection and treatment of cancer. We have developed and are testing early prototypes of an optical biopsy system (OBS) for detection of cancer and other tissue pathologies. The OBS invokes a unique approach to optical diagnosis of tissue pathologies based on the elastic scattering properties, over a wide range of wavelengths, of the microscopic structure of the tissue. The use of elastic scattering as the key to optical tissue diagnostics in the OBS is based on the fact that many tissue pathologies, including a majority of cancer forms, manifest significant architectural changes at the cellular and sub-cellular level. Since the cellular components that cause elastic scattering have dimensions typically on the order of visible to near-IR wavelengths, the elastic (Mie) scattering properties will be strongly wavelength dependent. Thus, morphology ...

1993-08-01

36

Intensive combined modality therapy including low-dose TBI in high-risk Ewing's sarcoma patients  

International Nuclear Information System (INIS)

Twenty-four high-risk Ewing's sarcoma patients were treated on an intensive combined modality protocol including low-dose fractionated total body irradiaiton (TBI) and autologous bone marrow infusion (ABMI). Twenty patients (83%) achieved a complete clinical response to the primary and/or metastatic sites following induction therapy. The median disease-free interval was 18 months, and nine patients remain disease-free with a follow-up of 22 to 72 months. Local failure as a manifestation of initial relapse occurred in only three patients (15%), each having synchronous distant failure. Eight patients failed initially with only distant metastases, usually within 1-2 years following a complete clinical response. Two patterns of granulocyte recovery following consolidative therapy (including TBI and ABMI) were recognized. The time to platelet recovery was different for the groups with early and late granulocyte recovery. ...

37

Change of the mass of an accelerated charge as a dynamic manifestation of the clock paradox  

Energy Technology Data Exchange (ETDEWEB)

Mass shift of accelerated charges-sources of a massive vector and massive scalar fields, are considered in an approximation which is classical with respect to the charge motion but quantum with respect to their interaction with their proper field. For uniformly accelerated charges the mass shifts are expressed in terms of cylindrical functions of the quantum parameter ..mu..c/sup 3//h/2..pi..w/sub 0/ which is the ratio of the mass ..mu.. of the proper field quanta to the charge acceleration w/sub 0/. For finite positive values of the parameter both the imaginary and real parts of the shifts are nonvanishing and negative. For ..mu -->..0 the real part of the mass shift of a vector charge tends to the classical value -..cap alpha..h/2..pi..w/sub 0//2c/sup 3/ obtained earlier, thereas that of the scalar charge tends to zero. These and other properties of the shifts as functions of ..mu.. are studied by taking into account the locality of interaction, unitarity and causality. Dispersion ...

1982-05-01

38

Cerebral and meningeal manifestations of AIDS: Sensitivity of CT and T sub 2 -weighted MR (129 patients). Zerebrale und meningeale Manifestation des AIDS: Sensitivitaet von CT und T sub 2 -gewichteter MRT (129 Patienten)  

Energy Technology Data Exchange (ETDEWEB)

We studied 129 AIDS patients with suspected or proved intracranial manifestations of the disease. The purpose of this study was to compare the diagnostic sensitivity of unenhanced and contrast enhanced CT and unenhanced T{sub 2}-weighted MR. Thus, in 20% of our patients MR but not CT was diagnostic. In another 20% MR provided additional diagnostic information. In conclusion, MR is recommended as the imaging modality of choice in AIDS patients with non-conclusive cranial CT. (orig./GDG).

1990-09-01

39

Use of acupuncture therapy as a supplement to conventional medical treatments for acute ischaemic stroke patients in an academic medical centre in Korea  

British Library Electronic Table of Contents (United Kingdom)

Objectives: Acupuncture has served as a major complementary and alternative therapy that supplements conventional medicine and is the subject of growing public interest. This study was conducted to estimate the usage rate of acupuncture as a supplemental treatment in acute ischaemic stroke patients and to identify factors associated with the choice to use this therapy. Methods: Using the registry of stroke patients admitted to an academic medical centre in Korea, the use of acupuncture therapy was recorded and analysed, along with the patients' socio-demographic characteristics, hospital access variables, risk factors for ischaemic stroke and clinical characteristics. The data were analysed using descriptive statistics, chi-square tests and multiple logistic regression analyses. Results: O...

2011-01-01

40

Two-year diagnostic stability in early-onset first-episode psychosis  

British Library Electronic Table of Contents (United Kingdom)

Background:- Only one study has used a prospective method to analyze the diagnostic stability of first psychotic episodes in children and adolescents. The Child and Adolescent First-Episode Psychosis Study (CAFEPS) is a 2-year, prospective longitudinal study of early-onset first episodes of psychosis (EO-FEP). Aim:- To describe diagnostic stability and the variables related to diagnostic changes. Methods:- Participants were 83 patients (aged 9-17-years) with an EO-FEP consecutively attended. They were assessed with a structured interview (Kiddie-Schedule for Affective Disorders and Schizophrenia, Present and Lifetime version) and clinical scales at baseline and after 2-years. Results:- The global consistency for all diagnoses was 63.9%. The small group of bipolar disorder had high stabilit...

2011-01-01

41

Sex determination using discriminant function analysis in children and adolescents: a lateral cephalometric study  

British Library Electronic Table of Contents (United Kingdom)

The objective of this study is to test the validity of sex determination in children and adolescents using lateral radiographic cephalometry and discriminant function analysis. Fifty male and 50 female cephalograms of Taiwanese children were used (males and females with mean age of 15.52???1.38 and 15.67???1.54?years, respectively). Twenty-two cephalometric measurements were performed using computerized cephalometry. Statistical analysis shows that all measurements were sexually dimorphic (p?clinically relevant, were used for discriminant function analysis. A stepwise discriminant procedure selected seven of the nine variables, producing 95% accuracy in sex determination. Resubstitution classification reveals the same discriminant rat...

2010-01-01

42

ST-segment changes after direct current external cardioversion for atrial fibrillation. Incidence, characteristics and predictive factors  

British Library Electronic Table of Contents (United Kingdom)

Background: Incidence, characteristics and predictive factors of transient ST-segment changes after DC shock are poorly known. Methods: 91 consecutive pts referred for external cardioversion of atrial fibrillation (AF) (61 men, 69+/-10yo) were prospectively included. The presence of ST elevation or depression was assessed on 12 lead-ECG immediately after the first DC shock. Correlations with DC shock characteristics (monophasic/biphasic and energy), clinical variables, echocardiographic parameters, biological parameters, medications, anesthesic drugs as well with morphological features were made. Results: 18 and 20 pts underwent 200J or 300J monophasic and 53 pts 200J biphasic DC shocks. We found an incidence of 48% for ST-segment changes: 35% for ST elevation and 13% for ST depression. ST...

2011-01-01

43

Outcomes and Cost Analysis of Pyeloplasty for Antenatally Diagnosed Ureteropelvic Junction Obstruction Using Markov Models  

British Library Electronic Table of Contents (United Kingdom)

Objectives The optimal timing of pyeloplasty for children diagnosed with ureteropelvic junction obstruction (UPJO) after workup for antenatal hydronephrosis is disputed. We sought to examine the potential costs and clinical outcomes of treatment protocols featuring different indications for pediatric pyeloplasty using Markov models. Methods Cost and outcomes analysis using Markov modeling was performed for three treatment algorithms: medical management, immediate pyeloplasty (during the first year of life), and pyeloplasty after no improvement on imaging. The costs were determined from the perspective of the medical institution. The variables tracked during Markov model simulation included age at resolution of UPJO, the proportion of patients with worsened hydronephrosis, the number of pye...

2008-01-01

44

Mutation analysis of KRAS prior to targeted therapy in colorectal cancer: development and evaluation of quality by a European external quality assessment scheme  

British Library Electronic Table of Contents (United Kingdom)

In Europe, the use of anti-EGFR monoclonal antibodies is restricted to Kirsten RAS (KRAS) wild-type colorectal tumors. Information on the KRAS status of the patients tumor is thus key for clinical practice; however, there is little guidance or definition on which KRAS mutations to assess and how to assess them. To ensure the consistency and the quality of KRAS test results in Europe, an interlaboratory control network needs to be set up. This pilot study aimed to identify the variables that need to be assessed in a quality control scheme and to provide a first assessment in a selected set of laboratories. Fourteen different tumor cases were circulated between 13 laboratories by a central laboratory acting as the referent for the mutation status determination. This study illustrated that of...

2011-01-01

45

Empirically defined subtypes of alcohol dependence in an Irish family sample  

British Library Electronic Table of Contents (United Kingdom)

Alcohol dependence (AD) is clinically and etiologically heterogeneous. The goal of this study was to explore AD subtypes among a sample of 1221 participants in the Irish Affected Sib Pair Study of Alcohol Dependence, all of whom met DSM-IV criteria for AD. Variables used to identify the subtypes included major depressive disorder, antisocial personality disorder, illicit drug dependence (cannabis, sedatives, stimulants, cocaine, opioids, and hallucinogens), nicotine dependence, the personality traits of neuroticism and novelty seeking, and early alcohol use. Using latent class analysis, a 3-class solution was identified as the most parsimonious description of the data. Individuals in a Mild class were least likely to have comorbid psychopathology, whereas a severe class had highest probabi...

2010-01-01

46

Delaying the superficial inferior epigastric artery flap: A solution to the problem of the small calibre of the donor artery  

British Library Electronic Table of Contents (United Kingdom)

Background: Superficial inferior epigastric artery (SIEA) flap has a great advantage over other flaps of the area, that is, readily non-existent donor-site problems. The main reason why the SIEA flap has never been extensively used in breast reconstruction is the small diameter and variable anatomy of its donor artery. This study presents a possibility of enlarging the SIEA diameter using the delay-phenomenon mechanism. Methods: A prospective clinical study of 26 patients was undertaken. Prior to surgery, ultrasound examinations were performed, measuring the diameter of SIEA and the velocity of blood flow in SIEA. The ipsilateral deep inferior epigastric artery (DIEA) was then ligated in all patients who had a measurable SIEA preoperatively. Two weeks later, measurements were repeated. The...

2011-01-01

47

Abces du muscle iliopsoas : complication rare de la sacro-iliite a pyogene chez lenfant  

British Library Electronic Table of Contents (United Kingdom)

Pyogenic sacroiliitis is a rare entity in children. Diagnosis is often delayed because of its variable clinical presentation, low suspicion by the examining physician, and rare findings on radiographs. Delayed diagnosis, however, results in complications such as iliopsoas abscess. We report the case of a 12-year-old girl hospitalized with a 21-day history of fever, pain in the left iliac fossa, and flexion contracture of the hip. On examination, she had fever (38.9 ^oC), psoitis, localized tenderness at the left sacroiliac joint, and pain elicited by lateral compression of the pelvis. The abdominal examination was normal. The erythrocyte sedimentation rate was 130mm in the first hour, C-reactive protein was 186mg/l, and the white blood cell count was 18,400/mm^3, with 79% neutrophils. Urin...

2010-01-01

48

The cardiomyopathy associated with methylsalicylate  

UK PubMed Central (United Kingdom)

Dogs challenged with toxic doses of methylsalicylate developed acute myocardiopathy. Metabolic manifestations of uncoupling of oxidative phosphorylation by methylsalicylate (MS) were observed. Oxygen...Full Text Available

1975-05-01

49

CASPAR: Low-Cost, Dual-Manifest Payload Adapter for ...  

Science.gov (United States)

... being designed for projected Minotaur IV launch load environments, with design objectives of light weight, integrated vibration isolation, low shock ...

2011-05-14

50

The helical tomotherapy thread effect  

International Nuclear Information System (INIS)

Inherent to helical tomotherapy is a dose variation pattern that manifests as a 'ripple' (peak-to-trough relative to the average). This ripple is the result of helical beam junctioning, completely unique to helical tomotherapy. Pitch is defined as in helical CT, the couch travel distance for a complete gantry rotation relative to the axial beam width at the axis of rotation. Without scattering or beam divergence, an analytical posing of the problem as a simple integral predicts minima near a pitch of 1/n where n is an integer. A convolution-superposition dose calculator (TomoTherapy, Inc.) included all the physics needed to explore the ripple magnitude versus pitch and beam width. The results of the dose calculator and some benchmark measurements demonstrate that the ripple has sharp minima near p=0.86(1/n). The 0.86 factor is empirical and caused by a beam junctioning of the off-axis dose profiles which differ from the axial profiles as well as a long scatter tail ...

2005-05-01

51

The clinical application of positron emission tomography to colorectal cancer management  

International Nuclear Information System (INIS)

Colerectal cancer (CRC) is the second commonest cancer in the Western World. Successful treatment relies significantly on accurate detection and staging of primary disease as well as the early identification of the presence and extent of recurrence. Morphological imaging techniques, particularly computed tomography (CT), are well established and widely available to carry out these tasks in addition to predicting and monitoring response to therapy. This review analyses the current inadequacies for imaging CRC and critically assesses the potential role of functional imaging with positron emission tomography (PET). It was reviewed the current literature, to use the experience from the firs 1000 PET studies carried out at the institution and the perspective of surgical colleagues. It was found little evidence for the use of 2-["1"8F]fluoro-2-deoxy-D-glucose (FDG)-PET for screening asymptomatic individuals and current modalities appear better suited for detection of symptomatic primary CRC. ...

2001-09-01

52

CT colonography: interpretative performance in a non-academic environment  

Energy Technology Data Exchange (ETDEWEB)

Aim: To investigate interpretative accuracy and reporting time for radiologists performing computed tomography (CT) colonography in day-to-day non-academic clinical practice. Materials and methods: Thirteen radiologists from seven centres, who were reporting CT colonography in non-academic daily clinical practice, interpreted a dataset of 15 colonoscopically validated cases in a controlled environment. Ten cases had either a cancer or polyp >10 mm; one case had a medium polyp and four were normal. Correct case categorization and interpretation times were compared using analysis of variance to aggregated results obtained from both experienced observers and observers recently trained using 50 cases, working in an academic environment. The effect of experience was determined using Spearman's rank correlation. Results: Individual accuracy was highly variable, range 53% (95% CI 27-79%) to 93% (95% CI 68-100%). ...

2007-05-15

53

Cutaneous manifestations in brucellosis.  

Science.gov (United States)

Brucellosis is a common worldwide zoonotic disease. Cutaneous manifestations are not specific and affect 1-14% of patients with brucellosis. Here, we describe 49-year-old female with fever and a diffuse maculopapular rash due to Brucella melitensis infection. Histopathology of skin biopsy revealed leukocytoclastic vasculitis; positive blood cultures for B. melitensis established the diagnosis of brucellosis. We provide a review of the relevant literature. PMID:21772606

2011-05-01

55

Interactions in multiple schedules: negative induction with squirrel monkeys1  

UK PubMed Central (United Kingdom)

In Experiment I, lever pressing by squirrel monkeys was maintained under a sequence of variable-interval, multiple variable-interval variable-interval, and multiple variable-interval extinction schedules...Full Text Available

1978-11-01

56

Treatment of skeletal class III malocclusions: orthognathic surgery or orthodontic camouflage? How to decide.  

Science.gov (United States)

The choice of treatment in adult skeletal Class III occlusions often poses a particularly tricky problem for the orthodontist. Faced with the option of either orthodontic camouflage or orthognathic surgery, the clinician's clinical experience is of paramount importance, especially in borderline cases. The aim of our study was to uncover a guide model enabling the practitioner to distinguish between skeletal Class III cases which can be suitably treated with orthodontics and those requiring orthognathic surgery. The lateral headfilms of 47 adult patients exhibiting skeletal Class III occlusions were analyzed. The orthodontic group comprised 22 patients and the surgical group 25. Twenty-seven linear, proportional and angular measurements were scrutinized. Stepwise discriminant analysis was used to identify the dentoskeletal and esthetic variables which most distinguished the two groups. The Holdaway angle was chosen to differentiate between ...

2011-04-20

57

Health-related quality of life following percutaneous coronary intervention: the impact of age on outcome at 1 year.  

Science.gov (United States)

This study was performed to assess the possibility that patient age may independently affect improvements in health-related quality of life following percutaneous coronary intervention. One hundred five patients undergoing elective percutaneous coronary intervention at a single tertiary referral center between January 10, 2001 and January 6, 2002 were enrolled and prospectively evaluated. Health-related quality of life was assessed before and 1 year following percutaneous coronary intervention using Short Form-12 and the Seattle Angina Questionnaire. For the purpose of analysis, patients were divided according to age (younger than 60, 60-70, and older than 70 years). One hundred patients (95%) completed both questionnaires. Baseline characteristics among the age groups were similar in terms of gender, cardiac risk factors, and procedural details. All health-related quality-of-life indices demonstrated improvements with at least four variables in each group ...

58

A YAC contig encompassing the recessive Stargardt disease gene (STGD) on chromosome 1p  

Energy Technology Data Exchange (ETDEWEB)

Stargardt disease (STGD) and fundus flavimaculatus are infrequent autosomal recessive conditions characterized by a juvenile macular dystrophy and variable degrees of peripheral retinal changes. Linkage analysis performed in 47 STGD/fundus flavimaculatus families demonstrated significant linkage to 13 polymorphic DNA markers on chromosome 1p. The maximum combined two-point lod score was 32.7 (maximum recombination fraction [{theta}{sub max}] = .006) with the polymorphic marker D1S188. Our data demonstrate that STGD and fundus flavimaculatus are the same disorder clinically and genetically and provide further evidence for genetic homogeneity of this phenotype. Analysis of recombination on disease chromosomes placed the STGD gene within a 4-cM interval between markers D1S435 and D1S236. A physical map was constructed of a YAC contig flanking STGD, from markers D1S500 to D1S495, and includes the critical interval delineated by historical ...

1995-12-01

59

Ultrasound-Guided Three-In-One Nerve Block for Femur Fractures  

UK PubMed Central (United Kingdom)

Femur fractures typically affect elderly patients with multiple co-morbidities. Pain control can be difficult, requiring intensive nursing and physician care as elderly patients may manifest cardiovascular...Full Text Available

2010-09-01

60

The use of etoricoxib to treat an idiopathic stabbing headache: a case report  

UK PubMed Central (United Kingdom)

According to the International Headache Society, idiopathic stabbing headache (ISH), an indomethacin-responsive headache syndrome, is a paroxysmal disorder of short duration manifested as head pain...Full Text Available

61

The use of advanced tracking technologies for the analysis of mobility in Alzheimer's disease and related cognitive diseases  

UK PubMed Central (United Kingdom)

BackgroundOne of the more common behavioral manifestations of dementia-related disorders is severe problems with out-of-home mobility. Various efforts have been attempted to attain...Full Text Available

62

The autoradiographic localization of paraquat in the lung  

International Nuclear Information System (INIS)

Paraquat poisoning in mammals results in a characteristic lung lesion manifested principally as progressive pulmonary fibrosis. Paraquat is actively concentrated into the lung but the site of uptake remains undefined. A method is described for the autoradiographic localization of paraquat in rats. Preliminary evidence for the site of uptake implicates the bronchiol. (author).

63

Reduced dopamine function within the medial shell of the nucleus accumbens enhances latent inhibition  

UK PubMed Central (United Kingdom)

Latent inhibition (LI) manifests as poorer conditioning to a CS that has previously been presented without consequence. There is some evidence that LI can be potentiated by reduced mesoaccumbal dopamine...Full Text Available

2011-03-01

64

Prenatal diagnosis for recessive dystrophic epidermolysis bullosa in 10 families by mutation and haplotype analysis in the type VII collagen gene (COL7A1).  

UK PubMed Central (United Kingdom)

BACKGROUND: Epidermolysis bullosa (EB) is a group of heritable diseases that manifest as blistering and erosions of the skin and mucous membranes. In the dystrophic forms of EB (DEB), the diagnostic...Full Text Available

1996-01-01

65

Oral manifestations of HIV infection in children and adults receiving highly active anti-retroviral therapy [HAART] in Dar es Salaam, Tanzania  

UK PubMed Central (United Kingdom)

BackgroundThe aim of the study was to compare the prevalence and types of HIV-related oral lesions between children and adult Tanzanian patients on HAART with those not on HAART...Full Text Available

66

Long-term disease-free survival after surgical resection for multiple bone metastases from rectal cancer  

UK PubMed Central (United Kingdom)

Bone metastasis of primary colorectal cancer is uncommon. When it occurs, it is usually a late manifestation of disease and is indicative of poor prognosis. We describe a patient with multiple metachronous...Full Text Available

2011-08-10

67

Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies  

UK PubMed Central (United Kingdom)

Recently, genome-wide association studies (GWAS) have linked the human LIN28B locus to height and timing of menarche [1-Full Text Available

2010-07-01

68

Imaging Findings of Localized Lymphoid Hyperplasia of the Pancreas: a Case Report  

UK PubMed Central (United Kingdom)

We report here on a case of localized lymphoid hyperplasia of the pancreas in a 70-year-old man which manifested as double lesions (uncinate process and tail) in the organ. The lesions were incidentally...Full Text Available

2011-07-01

69

High Contrast Near-infrared Polarized Reflectance Images of Demineralization on Tooth Buccal and Occlusal Surfaces at ?=1310-nm  

UK PubMed Central (United Kingdom)

Background and Objectives:Sound enamel manifests peak transparency in the near-IR (NIR) at 1310-nm, therefore the near-IR is ideally suited for high contrast imaging...Full Text Available

2009-03-01

70

FoxO Transcription Factors in Brain: Regulation and Behavioral Manifestation  

UK PubMed Central (United Kingdom)

BackgroundThe mammalian FoxO transcription factors function to regulate diverse physiological processes. Emerging evidence that both BDNF and lithium suppress FoxO...Full Text Available

2009-01-15

71

Double-Valve Libman-Sacks Endocarditis Causing Ventricular Fibrillation Cardiac Arrest  

UK PubMed Central (United Kingdom)

Libman-Sacks endocarditis is a well-known and rather common cardiac manifestation of systemic lupus erythematosus. Transesophageal and transthoracic echocardiography are the definitive imaging methods...Full Text Available

2011-01-01

72

Chromosome X modulates incidence of testicular germ cell tumors in Ter mice  

UK PubMed Central (United Kingdom)

Germ cell tumor development in humans has been proposed to be part of testicular dysgenesis syndrome (TDS), which manifests as undescended testes, sterility, hypospadias, and, in extreme cases,...Full Text Available

2007-12-01

73

Anchoring of a Single Molecular Rotor and Its Array on Metal Surfaces using Molecular Design and Self-Assembly  

UK PubMed Central (United Kingdom)

Functionalizing of single molecules on surfaces has manifested great potential for bottom-up construction of complex devices on a molecular scale. We discuss the growth mechanism for the initial layers...Full Text Available

74

Age- and Gender-Related Differences in the Geometric Properties and Biomechanical Significance of Intracortical Porosity in the Distal Radius and Tibia  

UK PubMed Central (United Kingdom)

Cortical bone contributes the majority of overall bone mass and bears the bulk of axial loads in the peripheral skeleton. Bone metabolic disorders often are manifested by cortical microstructural changes...Full Text Available

2010-05-01

75

Involvement of the chest and abdominal wall as a rare manifestation in Hodgkin's disease  

Energy Technology Data Exchange (ETDEWEB)

Radiological findings of chest and abdominal wall involvement in Hodgkin's disease are reported. This manifestation was diagnosed in one patient in the primary staging and in two patients during the course of the disease. Typical radiological findings are soft tissue masses in the chest and abdominal wall, in two cases with continous tumor growth of enlarged mediastinal lymphnodes into the anterior chest wall. The axial computed tomography is the best method to evaluate the extent of chest and abdominal wall involvement in Hodgkin's disease.

1983-03-01

76

Wide Differences in the Estimation of Cost in Endovenous Laser Therapy for Varicose Veins  

Science.gov (United States)

PURPOSE: To investigate differences in cost of endovenous laser therapy (EVLT) using a top-down approach derived from the Annual Report versus a clinically orientated, bottom-up approach at a single hospital. METHODS: Information was obtained from: the day-case activity Service Line Report (SLR) income statement for general surgery, comparative data from the National Audit Commission, reference costs from the hospital finance department on 69 patients and calculations on individual treatment times and session slots (2 EVLT's per 3.5 hr session) on 37 consecutive patients. Duration of treatment, consumables (over #3) and staff pay were also recorded. Overheads were estimated at 15% and adjustments were made based on location and length of stay. RESULTS: Using a top-down approach with SLR data the total cost of EVLT was estimated at #963.78 per treatment after adjustments for services and consumables. This compares with #1,073.34 using national data. The hospital ...

2011-08-01

77

Surgical adjuvant therapy in colon carcinoma: a human tumor spheroid model for evaluating radiation sensitizing agents  

International Nuclear Information System (INIS)

HT-29 human colon tumor cells growing as spheroids have been evaluated as a model system for measuring the response of human colon tumor cell to antineoplastic agents. HT-29 cells have been capacity to form spheroids up to 1 mm or more in diameter when grown in spinner culture. The multicellular HT-29 spheroids develop hypoxic centers reflecting the cellular conditions found in human cancer treatment, i.e., nutritionally deficient hypoxic cells that are felt to be a significant source of both radiation and chemotherapy clinical treatment failures. Spheroids of increasing size were radiated and then dispersed into single cells for colony survival assay. Compared with irradiated single cell suspensions, the spheroid cells demonstrated a significant increase in radioresistance. Growing spheroids developed a complex radiation survival curve which was variable with respect to size of the spheroid. The drug 5-Fu was studied to examine in a ...

78

Combined chemotherapy and radiotherapy: from biology to bed-side  

International Nuclear Information System (INIS)

Combination of radiotherapy and chemotherapy (CRC) is actually one important way of research in oncology. Theoretical advantages are: (1) Spatial cooperation; (2) Additivity, which is only obtained if the toxicity of each modality are different; (3) Supra-additivity, which needs a rigorous in vitro definition; the only way to prove it is to make an isobologram analysis. This model has however, some limitations: qualitative variable could not be used, results could be different, depending on the cell line and isoeffect chosen...In fact, a supra-additivity was only demonstrated for cis platinum and etoposide. Interactions mechanisms were: (1) at the molecular level, creation of new lesions or inhibition of radiation lesions repair; (2) At the cellular level, either cytokinetic cooperation with S-phase dependent drugs, or synchronization for the drugs which blocked the cells in M-phase; (3) At the tissular level, reoxygenation, cycle redistribution. In ...

84

Clinical Digital Libraries Project: design approach and exploratory assessment of timely use in clinical environments*  

UK PubMed Central (United Kingdom)

Objective: The paper describes and evaluates the use of Clinical Digital Libraries Project (CDLP) digital library collections in terms of their facilitation of timely clinical information...Full Text Available

2006-04-01

86

Variable elimination in chemical reaction networks with mass action kinetics  

CERN Document Server

We consider chemical reaction networks taken with mass action kinetics. The steady states of such a system are solutions to a system of polynomial equations. Even for small systems the task of finding the solutions is daunting. We develop an algebraic framework and procedure for linear elimination of variables. The procedure reduces the variables in the system to a set of "core" variables by eliminating variables corresponding to a set of non-interacting species. The steady states are parameterized algebraically by the core variables, and a graphical condition is given for when a steady state with positive core variables necessarily have all variables positive. Further, we characterize graphically the sets of eliminated variables that are constrained by a conservation law and show that this conservation law takes a ...

2011-01-01

87

Pathology of tissue loss (white syndrome) in Acropora sp. corals from the Central Pacific.  

Science.gov (United States)

We performed histological examination of 69 samples of Acropora sp. manifesting different types of tissue loss (Acropora White Syndrome-AWS) from Hawaii, Johnston Atoll and American Samoa between 2002 and 2006. Gross lesions of tissue loss were observed and classified as diffuse acute, diffuse subacute, and focal to multifocal acute to subacute. Corals with acute tissue loss manifested microscopic evidence of necrosis sometimes associated with ciliates, helminths, fungi, algae, sponges, or cyanobacteria whereas those with subacute tissue loss manifested mainly wound repair. Gross lesions of AWS have multiple different changes at the microscopic level some of which involve various microorganisms and metazoa. Elucidating this disease will require, among other things, monitoring lesions over time to determine the pathogenesis of AWS and the potential role of tissue-associated microorganisms in the genesis of tissue loss. ...

2011-03-30

88

Renormalization of Lorentz non-invariant actions and manifest T-duality  

CERN Document Server

We study general two-dimensional sigma-models which do not possess manifest Lorentz invariance. We show how demanding that Lorentz invariance is recovered as an emergent on-shell symmetry constrains these sigma-models. The resulting actions have an underlying group-theoretic structure and resemble Poisson--Lie T-duality invariant actions. We consider the one-loop renormalization of these models and show that the quantum Lorentz anomaly is absent. We calculate the running of the couplings in general and show, with certain non-trivial examples, that this agrees with that of the T-dual models obtained classically from the duality invariant action. Hence, in these cases solving constraints before and after quantization are commuting operations.

2009-01-01

93

Lead-203 for skeletal imaging  

International Nuclear Information System (INIS)

... biological variability body distribution kidneys labelled compounds lead 203

95

Is uniform target dose possible in IMRT plans in the head and neck?  

International Nuclear Information System (INIS)

Purpose: Various published reports involving intensity-modulated radiotherapy (IMRT) plans developed using automated optimization (inverse planning) have demonstrated highly conformal plans. These reported conformal IMRT plans involve significant target dose inhomogeneity, including both overdosage and underdosage within the target volume. In this study, we demonstrate the development of optimized beamlet IMRT plans that satisfy rigorous dose homogeneity requirements for all target volumes (e.g., #+-#5%), while also sparing the parotids and other normal structures. Methods and Materials: The treatment plans of 15 patients with oropharyngeal cancer who were previously treated with forward-planned multisegmental IMRT were planned again using an automated optimization system developed in-house. The optimization system allows for variable sized beamlets computed using a three-dimensional convolution/superposition dose calculation and flexible cost functions derived ...

2002-04-01

96

Use of an Orientation Clinic to Reduce Failed New Patient Appointments in Primary Care  

UK PubMed Central (United Kingdom)

Patients who fail to attend initial appointments reduce clinic efficiency. To maximize attendance by newly referred outpatients, we introduced a mandatory group orientation clinic for all new patients...Full Text Available

2000-12-01

97

The Clinical and Radiological Outcomes of Minimally Invasive Transforaminal Lumbar Interbody Single Level Fusion  

UK PubMed Central (United Kingdom)

Study DesignThis is a retrospective study that was done according to clinical and radiological evaluation.PurposeWe analyzed the clinical and radiological...Full Text Available

2011-06-01

98

Standardization of clinical decision making for the conduct of credible clinical research in complicated medical environments.  

UK PubMed Central (United Kingdom)

The likelihood that past experience will produce correct guides to current practice depends on the signal-to-noise ratio for the clinical problem of interest. If the signal-to-noise ratio is high, the...Full Text Available

1996-01-01

99

Implementing a Web-based clinical information system using EMR middle layer services.  

UK PubMed Central (United Kingdom)

The Clinical Summary is a Web-based application for accessing the clinical database at the Massachusetts General Hospital. The application has been developed to give physicians in our health care community...Full Text Available

1996-01-01

100

Impact and User Satisfaction of a Clinical Information Portal Embedded in an Electronic Health Record  

UK PubMed Central (United Kingdom)

In 2008, a clinical information tool was developed and embedded in the electronic health record system of an academic medical center. In 2009, the initial information tool, Clinical-e, was superseded...Full Text Available

101

Comparing the Diagnostic Performance of 2 Clinical Decision Rules to Rule Out Deep Vein Thrombosis in Primary Care Patients  

UK PubMed Central (United Kingdom)

PURPOSE The Wells rule is widely used for clinical assessment of patients with suspected deep vein thrombosis (DVT), especially in the secondary care setting. Recently a new clinical decision...Full Text Available

2011-01-01

102

Clinical Signs and Pathology of Accidental Monensin Poisoning in Sheep  

UK PubMed Central (United Kingdom)

The clinical signs and postmortem findings in sheep from two flocks accidentally poisoned with monensin are described. Clinical signs began within 24 hours of exposure to monensin. In the acute stages...Full Text Available

1982-11-01

103

Confrontation between stellar pulsation and evolution; Proceedings of the Conference (ASP Series, Vol. 11), Bologna, Italy, May 28-31, 1990  

International Nuclear Information System (INIS)

Attention is given to the folowing topics: population I and II variable stars; LP variables, the sun, and mass determination; and predegenerate and degenerate variables. Particular papers are presented on alternative evolutionary approaches to the absolute magnitude of the RR Lyrae variables; the evolution of the Cepheid stars; nonradial pulsations in rapidly rotating Delta Scuti stars; dynamical models of dust shells around Mira variables; and pulsations of central stars of planetary nebulae.

1990-05-28

104

Transforming Clinic Environments into Information Workspaces for Patients  

UK PubMed Central (United Kingdom)

Although clinic environments are a primary location for exchanging information with clinicians, patients experience these spaces as harsh environments to access, use, exchange, and manage information....Full Text Available

2010-01-01

105

Specialist clinics: a better way to care?  

UK PubMed Central (United Kingdom)

A questionnaire on the development of specialist clinics was distributed to the members of the Association of British Neurologists and completed by 104 members (85 consultants). Half of the respondents...Full Text Available

1992-03-01

106

Read Code Quality Assurance  

UK PubMed Central (United Kingdom)

As controlled clinical vocabularies assume an increasing role in modern clinical information systems, so the issue of their quality demands greater attention. In order to meet the resulting stringent...Full Text Available

1998-07-01

107

Curvularia keratitis.  

UK PubMed Central (United Kingdom)

PURPOSE: To determine the risk factors and clinical signs of Curvularia keratitis and to evaluate the management and outcome of this corneal phaeohyphomycosis. METHODS: We reviewed clinical and laboratory...Full Text Available

2001-01-01

108

Clinical spectrum  

Energy Technology Data Exchange (ETDEWEB)

A tunable diode laser is used to obtain infrared spectra of carbon dioxide in biological materials. The spectral resolution is sufficient to readily distinguish differing isotopic species. The technique may prove useful in clinical tests.

1987-11-01

109

Clinical significance of coagulase-negative staphylococci.  

UK PubMed Central (United Kingdom)

Although coagulase-negative staphylococci (C-NS) have been implicated in certain human infections, they are generally regarded as contaminants, and their clinical significance is questioned. To assess...Full Text Available

1982-08-01

110

Clinical decision support: progress and opportunities  

UK PubMed Central (United Kingdom)

In 2005, the American Medical Informatics Association undertook a set of activities relating to clinical decision support (CDS), with support from the office of the national coordinator and the Agency...Full Text Available

2010-09-01

111

Clinical Recovery in First-Episode Psychosis  

UK PubMed Central (United Kingdom)

Introduction: Generally agreed outcome criteria in psychosis are required to evaluate the effectiveness of new treatment strategies. The aim of this study is to explore clinical recovery...Full Text Available

2009-03-01

112

Clinical Characteristics and Outcomes of Cataract Surgery in Highly Myopic Koreans  

UK PubMed Central (United Kingdom)

PurposeTo evaluate the clinical characteristics and outcomes of cataract surgery in highly myopic Korean subjects.MethodsWe retrospectively reviewed...Full Text Available

2011-04-01

113

Association of upper gastrointestinal symptoms with functional and clinical charateristics in elderly  

UK PubMed Central (United Kingdom)

AIM: To evaluate the prevalence of upper gastrointestinal symptoms and their association with clinical and functional characteristics in elderly outpatients.METHODS: The study involved 3238 outpatients...Full Text Available

2011-07-07

114

Silica, silicosis and tuberculosis.  

Science.gov (United States)

Exposure to crystalline silica dust causes multiple diseases, but silicosis and silica dust-associated tuberculosis (TB), in particular, are the two diseases that remain high on the list of occupational health priorities in low-income countries and that still occur in some high-income countries. The prevalence of silica-related TB is exacerbated by the human immunodeficiency virus (HIV) epidemic in low-income countries. This review describes the morphology of silica and the variable potency of the different forms. Sources of crystalline silica are discussed, with emphasis on less commonly recognised sources, such as small-scale mining operations and agriculture. Trends in the prevalence of silicosis are also presented. Although efforts have been made for many years in most countries to reduce silica dust levels, silicosis continues to occur even in young people. The clinical and pathological features and diagnosis of silicosis, with emphasis on ...

2007-05-01

115

Screening for von Willebrand disease: contribution of an automated assay for von Willebrand factor activity.  

Science.gov (United States)

Summary.? Measuring von Willebrand factor (VWF) activity is essential to the diagnosis of von Willebrand disease (VWD). The VWF activity is usually assessed based on measurement of the ristocetin cofactor (VWF:RCo). However, that test is technically challenging and has high intra- and inter-assay variabilities. The HemosIL VWF activity (VWF:AC) is a fully automated assay, recently proposed as a good alternative to VWF:RCo for VWD diagnosis. This study was undertaken to assess this new method. First, the analytical performance of VWF:AC on an automated coagulo-meter (ACLTop) was determined, and then this new method was compared with VWF:RCo and the platelet function analyzer (PFA100) for 160 patients referred for VWD screening. The VWF:AC achieved acceptable precision with within-run and between-run coefficients of variation ranging from 2.3% to 14.1%, and linearity from 10% to 100%. Despite some marked differences between VWF:AC and VWF:RCo for 10 plasmas tested, ...

2011-09-28

116

Endovenous radiofrequency ablation using stent-type electrode for varicose veins: an experimental study in goats  

Energy Technology Data Exchange (ETDEWEB)

The purpose of this study was to investigate the feasibility and the optimal conditions of radiofrequency (RF) ablation by using the stent-type electrode upon the saphenous vein of goats for the endovenous treatment of varicose veins. A self-expandable nitinol stent electrode (6 mm diameter, 2 cm length, cell size; 1.3 x 2 mm) was designed to expose the distal 1 cm segment to allow for contact with the venous wall. The proximal part of the electrode was connected to the RF generator by insulated copper wires located within the stent electrode introducer. Initially, to optimize the power setting, ablation of 6 saphenous veins in 3 goats was performed with power settings of 10, 20 and 30 W. Pull back rate of the electrode was 2 and 4 cm/min for each power level, respectively. The goats were sacrificed 4-6 weeks later and histologic examinations of the saphenous veins were done. For the second part of the experiment, RF ablation of 4 saphenous veins from 2 goats was done by applying the ...

2004-10-15

117

Design variables for mechanical properties of bone tissue scaffolds.  

Science.gov (United States)

The reconstruction of segmental defect in long bone is a clinical challenge. Multiple surgeries are typically required to restore the structure and function of the affected defect site. In order to overcome this defect a biodegradable bone tissue engineering scaffold is used. This scaffold acts as a carrier of proteins and growth factors, while also supporting the load that the bone would normally sustain, until the natural bone can regenerate in its place. Work was done to optimize an existing solid free-form scaffold design. The goal of the optimization was to increase the porosity of the scaffold while maintaining the strength of a previously-tested prototype design. With this in mind, eight new designs were created. These designs were drawn using CAD software and then through the use of finite element analysis the theoretical ultimate compressive strength of each design was obtained. Each scaffold design was constructed by casting a thermal-curable ...

2006-01-01

118

Current Status on Stress Diagnostic Kit and Detection Technology  

Energy Technology Data Exchange (ETDEWEB)

The accurate measurement of a stress level is one of the most important issues in a stress diagnosis and its measurement could be of great value in clinical medicine. Stress has a potent effect on the spirit and physical condition of an individual. There are various methods available for its measurement. Some of the commonly used techniques for the diagnosis of a stress level include analysis of the body fluids, questionnaire assessments, psychophysiological evaluations and by determining heart rate variability (HRV) of subjects. However, the existing diagnostic methods have several defects like, a low sensitivity, inaccuracy and long of operation time. In this report, we present a diagnostic technology to detect a stress level which is the origin of various diseases. This method can be of great help in providing an early diagnosis through a biosensor and might play a vital role in preventing diseases like hypochondria and hypertension. ...

2008-06-15

119

Comparison of medetomidine and fentanyl-droperidol in dogs: sedation, analgesia, arterial blood gases and lactate levels.  

Science.gov (United States)

Medetomidine and fentanyl-droperidol (Innovar-vet) were assessed over a three hour period in 80 healthy dogs. Following physical examination, electrocardiogram (ECG), arterial blood sample analysis, and dynamometer pressure threshold (analgesia score), the dogs were randomly assigned to one of four treatments: Miv--medetomidine (750 micrograms/M2) administered intravenously (IV), Mim--medetomidine (1000 micrograms/M2) administered intramuscularly (IM), Iiv--Innovar-vet IV (0.05 mL/kg) or Iim--Innovar-vet IM (0.1 mL/kg). All assessments were carried out by a single individual unaware of the treatment used. Objective assessments included temperature, heart and respiratory rates, analgesia score, arterial blood gases, acid-base and lactate levels. Subjective evaluation included degree of sedation, response to various clinical procedures, noise responsiveness, posture, and the incidence of side effects. Onset and duration of effect were also recorded. The ECG strips ...

1993-04-01

120

Cardiac Malpositions  

International Nuclear Information System (INIS)

Cardiac Malposition refers to any position of the heart other than a left-sided heart in a situs solitus individual. Associated cardiac malformations are so complex that even angiocardiographic and autopsy studies may not afford an accurate information. Although the terms and classifications used to describe the internal cardiac anatomy and their arterial connections in cardiac malpositions differ and tend to be confusing, common agreement exists on the need for a segmental approach to diagnosis. Authors present 18 cases of cardiac malpositions in which cardiac catheterization and angiocardiography were done at the Department of Radiology, Seoul National University Hospital between 1971 and 1979. Authors analyzed the clinical, radiographic, operative and autopsy findings with the emphasis on the angiocardiographic findings. The results are as follows: 1. Among 18 cases with cardiac malpositions, 6 cases had dextrocardia with situs inversus, 9 cases had dextrocardia ...

1979-06-01

121

Brain SPECT of chronic fatigue syndrome (CFS): SPM analysis of two age groups  

International Nuclear Information System (INIS)

Full text: Chronic fatigue syndrome (CFS) is a complex disorder characterised by profound fatigue and neuropsychiatric dysfunction. Previous studies with cerebral perfusion SPECT (rCBF) scans were performed with inhomogeneous patient populations and were not analysed with Statistical Parametric Mapping (SPM). We have used SPM to study subjects with moderate CFS based on the Fukuda criteria, who were not on medication and not depressed, compared to age matched control subjects. An apparent bimodal age distribution has been observed in CFS. Subjects were therefore divided into two age groups: 16-35 or under 35 (17 CFS, 11 control) and 36-61 or over 35 (15 CFS, 15 control). HMPAO brain SPECT was acquired on a 3-head camera. After lower window scatter subtraction, reconstruction with attenuation correction (mu=0.15/cm) and editing of facial activity, scans were spatially normalised (affine + 2x3x2 nonlinear) to SPM's anatomical space. SPM statistical analysis yielded the location, ...

2002-05-04

122

Attitudes toward obesity in obese persons: a matched comparison of obese women with and without binge eating.  

Science.gov (United States)

No research has compared expressions of weight bias across different subgroups of obese individuals. This study compared attitudes toward and beliefs about obesity in women with and without binge eating disorder (BED) and examined whether these attitudes are related to psychological factors. Fifty obese women with BED were compared with an age- and body mass index (BMI)-matched group of 50 obese women without BED on a battery of established measures of anti-fat attitudes and beliefs about weight controllability and psychological factors (self-esteem, depression, and eating disorder features). The ageand BMI-matched groups did not differ with respect to beliefs about obesity or attitudes toward obese persons, or in self-esteem or depression. Correlational analyses conducted separately within each group revealed that women with BED who reported more favorable attitudes towards obese persons had higher self-esteem and lower levels of depression, whereas there were no significant ...

2010-01-27

123

A pain management program for chronic cancer-treatment-related pain: a preliminary study.  

Science.gov (United States)

A large proportion of patients may develop chronic pain following cancer treatments such as surgery, radiotherapy, or chemotherapy. These patients can experience significant levels of physical and psychological morbidity. Our aim was to investigate a cognitive-behavioral pain management program (PMP) for cancer patients with chronic treatment-related pain. Thirteen patients (1 man, 12 women; mean age 52 yrs) completed the study, 9 of whom had a history of breast cancer and had received extensive medical treatment, including surgery. A combination of physical and psychological techniques were adapted from previous work in chronic benign pain and implemented by two therapists. Interventions included education, relaxation, exercise training, and goal setting. A variety of outcomes were examined to assess general fitness, psychological distress, coping success, activities of daily living, and pain report. The median number of interventions by each therapist was 10 (4 to 15). ...

2006-02-01

124

Transient enhanced diffusion of oxygen in Fe mediated by large electronic excitation  

International Nuclear Information System (INIS)

Contrary to the electronic excitation induced phenomena of desorption and sputtering, we observed incorporation of oxygen in a thin Fe film during its irradiation with swift heavy ions. It is observed that the adsorbed oxygen diffuses in to the Fe film. The incorporation of oxygen and its diffusion in the bulk of the film is a manifestation of extremely large electronic energy deposition by the incident ions. It is shown that the experimentally observed high diffusivity of oxygen in Fe during irradiation is due to the existence of transient melt phase of Fe.

2003-10-15

125

SO(5,5) duality in M-theory and generalized geometry  

CERN Document Server

We attempt to reformulate eleven dimensional supergravity in terms of an object that unifies the three-form and the metric and makes the M-theory duality group manifest. This short note deals with the case of where the U-duality group SO(5,5) acts in five spatial dimensions.

2011-01-01

126

Osteonecrosis in patients receiving dialysis: report of two cases and review of the literature.  

Science.gov (United States)

Two patients receiving maintenance dialysis therapy developed osteonecrosis, the first in the humeral head and the second in the talus. Both patients lacked known risk factors for developing osteonecrosis. A possible pathogenic role of secondary hyperparathyroidism in this disorder is suggested. Rheumatologists evaluating patients receiving maintenance dialysis with rheumatic manifestations should be aware of this potential complication. PMID:2185360

1990-03-01

127

On the unitarity of string propagation on SU(1,1)  

Energy Technology Data Exchange (ETDEWEB)

The authors discuss the consistency (unitarity) of string propagation on the non-compact group SU(1,1) {times} G{sub c} and find the restriction on the level of the Kac-Moody algebra for this propagation to be unitary. They also suggest some modifications to the Virasoro generators and obtain a manifestly unitary string theory.

1990-08-20

128

Lyme myocarditis diagnosed by indium-111-antimyosin antibody scintigraphy  

Energy Technology Data Exchange (ETDEWEB)

We report a new case of Lyme disease with cardiac manifestations, which has been possible to follow during the long period of 12 years. We have detected the usual ECG abnormalities, and concentric hypertrophic myocardiopathy, by echocardiography. The acute myocarditis was demonstrated by /sup 111/In-antimyosin scintigraphy, which showed global myocardial uptake of the tracer, constituting the first report, to our knowledge, of Lyme myocarditis diagnosed by this method.

1989-06-01

129

Localized Rayleigh Instability in Evaporation Fronts  

CERN Document Server

A qualitatively different manifestation of the Rayleigh instability is demonstrated, where, instead of the usual extended undulations and breakup of the liquid into many droplets, the instability is localized, leading to an isolated narrowing of the liquid filament. The localized instability, caused by a nonuniform curvature of the liquid domain, plays a key role in the evaporation of thin liquid films off solid surfaces.

2009-01-01

130

Corrosion resistance of metals in hot hydroxide solutions  

International Nuclear Information System (INIS)

Effect of hydroxide nature, concentration and temperature on corrosion resistance of domestic steels and alloys to hot NaOH, KOH, LiOH solutions is considered. It is ascertained that by corrosion growth in relation to stainless steels and nickel alloys, the hydroxides are placed in the following sequence: LiOHmanifested, are determined. 12 refs., 12 figs.

131

Computed tomography of intrahepatic cholangiocarcinoma  

International Nuclear Information System (INIS)

Intrahepatic cholangiocarcinoma is an uncommon tumor as primary hepatic neoplasm. Five cases of cholangiocarcinoma, mass forming peripheral type, are reported about its CT findings. They were manifested as a poorly marginated low density mass with a irregular stellate area. In one case, a cut section of the gross specimen following surgery showed a central callagenous scar and vessels within the necrotic tumor. (author).

132

CT manifestations of ileal dysgenesis  

Energy Technology Data Exchange (ETDEWEB)

Ileal dysgenesis is an uncommon condition of unknown etiology occurring in the distal ileum in the region of the vitelline duct. The CT appearance of this lesion, although not previously described to our knowledge, is characteristic. We report a patient with ileal dysgenesis who had an abdominal CT scan to evaluate chronic iron deficiency anemia and protein-losing enteropathy. Recognition of this lesion by pediatric radiologists is important; so that surgical treatment, which is simple and effective, can be initiated quickly. (orig.)

2007-02-15

133

Bilateral enlargement of the orbital muscles: first manifestation of renal adenocarcinoma; Espessamento da musculatura extrinseca orbitaria bilateralmente: manifestacao primaria de adenocarcinoma renal  

Energy Technology Data Exchange (ETDEWEB)

The authors present an unusual case of a patient with orbital metastases from renal carcinoma involving the extra ocular muscles bilaterally. The importance of computed tomography for the differential diagnosis with other orbital lesions is emphasized. (author)

2000-06-01

134

Alignments of multi-quasiparticle bands and seniority-dependent reduced pairing  

Energy Technology Data Exchange (ETDEWEB)

Pairing correlations in multi-quasiparticle states in deformed nuclei are expected to be reduced because of blocking. New intrinsic states and their associated rotational bands have been identified allowing comparisons to be made as a function of seniority and between nuclei. The possible effects of the reduced pairing on the collective rotation, and its manifestation in terms of alignment, are discussed. 13 refs., 2 figs.

1994-09-01

135

A class of finite one-loop light-cone integrals  

Energy Technology Data Exchange (ETDEWEB)

Using the manifestly causal gluon propagator in the light-cone gauge, we evaluate two one-loop Feynman integrals which appear in the computation of the three-gluon vertex correction in the two-component formalism of the Yang-Mills gauge fields. We conclude that they both are finite for {omega} -> 2, where {omega} is the dimensional regulator. They belong to a class of finite one-loop light-cone integrals. (author). 7 refs.

1992-10-01

142

Dioxins in the Baltic sea  

Wastenet

for municipal waste iron ore sinter plants incinerators for clinical waste facilities of the non-ferrous metal

149

ADULT ACQUIRED TOLERANCE TO HOMOGRAFTS.  

Science.gov (United States)

... The effectiveness of immune suppression with both 6-mercaptopurine and methotrexate was insufficient to permit induction of a clinically useful ...

1967-07-31

151

Variable Pathogenicity Determines Individual Lifespan in Caenorhabditis elegans  

UK PubMed Central (United Kingdom)

A common property of aging in all animals is that chronologically and genetically identical individuals age at different rates. To unveil mechanisms that influence aging variability, we identified markers...Full Text Available

2011-04-01

152

Variability In Motor Learning: Relocating, Channeling and Reducing Noise  

UK PubMed Central (United Kingdom)

Variability in motor performance decreases with practice but is never entirely eliminated, due in part to inherent motor noise. The present study develops a method that quantifies how performers...Full Text Available

2009-02-01

153

The Characterisation of Three Types of Genes that Overlie Copy Number Variable Regions  

UK PubMed Central (United Kingdom)

BackgroundDue to the increased accuracy of Copy Number Variable region (CNV) break point mapping, it is now possible to say with a reasonable degree of confidence whether a gene...Full Text Available

154

Numerical optimization of spherical variable-line-spacing grating X-ray spectrometers  

UK PubMed Central (United Kingdom)

Operation of an X-ray spectrometer based on a spherical variable-line-spacing (VLS) grating is analyzed using dedicated ray-tracing software allowing fast optimization of the grating parameters and...Full Text Available

2011-03-01

155

Intra-Individual Variability in Alzheimer's Disease and Cognitive Aging: Definitions, Context, and Effect Sizes  

UK PubMed Central (United Kingdom)

Background/AimsTo explore different definitions of intra-individual variability (IIV) to summarize performance on commonly utilized cognitive tests (Mini Mental State Exam; Clock...Full Text Available

156

Guided Cell Migration on Microtextured Substrates with Variable Local Density and Anisotropy  

UK PubMed Central (United Kingdom)

This work reports the design of and experimentation with a topographically patterned cell culture substrate of variable local density and anisotropy as a facile and efficient platform to guide...Full Text Available

2009-02-06

157

Considerable Variability in Platelet Activity among Patients with Coronary Artery Disease in Response to an Increased Maintenance Dose of Clopidogrel  

UK PubMed Central (United Kingdom)

BackgroundVariable platelet response to clopidogrel has been widely observed. Studies have shown that the mean aggregation response to clopidogrel can be changed...Full Text Available

2009-05-01

158

Adaptive Thresholding for Improving Sensitivity in Single-Trial Simultaneous EEG/fMRI  

UK PubMed Central (United Kingdom)

A common approach used to fuse simultaneously recorded EEG and fMRI is to correlate trial-by-trial variability in the EEG, or variability of components derived therefrom, with the blood oxygenation...Full Text Available

161

Mira variables - Pulsation, mass loss and evolution  

International Nuclear Information System (INIS)

Recent developments in the analysis of Mira atmosphere, the determination of the pulsation mode, the problem of mass loss, and the evolution of the Mira variables are covered. Model atmospheres for Mira variables, including the opacities of the molecules expected in very late M-type atmospheres are discussed. The pulsation constant for Omicron Ceti is evaluated using T(eff) = 2900 + or - 200 K, and it is concluded that Miras are fundamental mode pulsators. The importance of molecular opacity to the driving of mass loss is evaluated, and it is pointed out that the radiation pressure on molecules is not a major factor in driving mass loss from Mira. Mass loss is considered as a factor in the calculations of the periods for Mira variables. 30 refs.

1990-05-28

162

Asymptotic functions of many variables and singular operations with Schwartz distributions  

International Nuclear Information System (INIS)

A theory of the asymptotic functions for the case of many variables is presented. It is shown that the class F(R"N) of these generalized functions is closed in respect to the linear algebraic and analytic operations, multiplication as well as a set of linear and polynomial changes of the variables. The existence in F(R"N) of analogues (consistent with the linear operations) of the Schwartz distributions with point support is proved. In terms of these analogues, some formulae for singular products and changes of variables of the Dirac #delta#-function and its derivatives #delta#"("i")(x), x is an element of R"N, are given. (author). 14 refs.

1992-10-19

163

A Simulation Model for Estimating Airport Terminal Area ...  

Science.gov (United States)

... AIR TRAFFIC, TERMINAL FLIGHT ... FLIGHT, RANDOM VARIABLES, STOCHASTIC PROCESSES ... COMPUTER PROGRAMS, QUEUEING THEORY. ...

1971-05-01

164

Variable-speed hydro evolves  

Energy Technology Data Exchange (ETDEWEB)

Success in improving hydropower project efficiency has opened more global markets for variable-speed generator technology. Manufacturers continue to test the markets as the technology evolves. The potential of variable-speed application becomes evident considering that more than 150 pumped storage plants, with a combined capacity exceeding 100,000 MW, are in operation globally.

1993-10-01

165

Tidal spin-up and magnetic braking in cataclysmic variables  

International Nuclear Information System (INIS)

Based on proposed models for the tidal spin-up and magnetic braking of stars with a convective outer envelope, it is suggested that the rotation of secondaries in cataclysmic variables is not necessarily synchronized with the orbital revolution. This may provide an explanation for the observed large range in the mass transfer rate (at the same orbital period) of cataclysmic variables above the period gap. (author).

166

Moderate deviations for stationary sequences of Hilbert valued bounded random variables  

CERN Document Server

In this paper, we derive the moderate deviation principle for stationary sequences of bounded random variables with values in a Hilbert space. The conditions obtained are expressed in terms of martingale-type conditions. The main tools are martingale approximations and a new Hoeffding inequality for non adpated sequences of Hilbert-valued random variables. Applications to Cramer-Von Mises statistics, functions of linear processes and stable Markov chains are given.

2008-01-01

167

Long-run determinants of pollution: A robustness analysis  

British Library Electronic Table of Contents (United Kingdom)

This paper examines how robust economic, political, and demographic variables are related to water and air pollution. Employing Bayesian Averaging of Classical Estimates (BACE) for a cross section of 47 countries, 34 variables and 3 proxies for air and water pollution over a period from 1980 to 2000 we confirm the environmental Kuznets curve hypothesis and highlight the relevance of variables that are not directly related to production.

2009-01-01

168

Joint distributions and tachyons  

International Nuclear Information System (INIS)

In recent years there has been a renewed interest in the treatment of quantum mechanics in terms of joint distribution functions, i.e. functions of momentum and position coordinates p and q. The author considers j.d.f. in the sense of classical probability theory of a stochastic variable. The j.d.f. is then interpreted as the probability that the variables p and q have certain values, the variables being considered as a property possessed by the object system. This formalism is used to provide a unified description of bradyons and tachyons. (Auth.).

169

EUVE Observations of Nonmagnetic Cataclysmic Variables  

Energy Technology Data Exchange (ETDEWEB)

The authors summarize EUVE's contribution to the study of the boundary layer emission of high accretion-rate nonmagnetic cataclysmic variables, especially the dwarf novae SS Cyg, U Gem, VW Hyi, and OY Car in outburst. They discuss the optical and EUV light curves of dwarf nova outbursts, the quasi-coherent oscillations of the EUV flux of SS Cyg, the EUV spectra of dwarf novae, and the future of EUV observations of cataclysmic variables.

2001-09-05

170

Circadian and circatrigintan respiratory and related intermodulations in the crab Barytelphusa guerini.  

Science.gov (United States)

Respiration and related physiologic variables in different tissues of Barytelphusa guerini and the respiration of this freshwater crab as a whole are closely synchronized in phase and in frequency along the circadian scale, in the face of large differences in circadian amplitude. A very close timing of most of the 36 variables examined in 2 separate circadian profiles and a modulation of some of these variables in added profiles as a function of lunar stage are clearly demonstrable, statistically significant and illustrative of time relations at 2 interacting frequencies. PMID:6745009

171

On the development of a new methodology for groundwater-driven health risk assessment  

Science.gov (United States)

A methodology and hypothetical case study are presented for incorporation of uncertainty and variability into calculations of human health risk appropriate for regional, or basin-scale, groundwater management problems. Uncertainty in well water concentration is introduced through complex contaminant migration patterns in the subsurface. Variability is considered in parameters related to individual behavior patterns and biological effects and to groundwater extraction and distribution networks. A joint uncertainty and variability (JUV) analysis is used to generate a two-dimensional distribution or risk surface that spans both transport uncertainty as well as individual variability. Cuts in this distributional surface (fractiles of variability and percentiles of uncertainty) are presented and discussed. Comparisons with alternative approaches based upon deterministic transport models ...

1998-01-01

172

Supersymmetry on the Run: LHC and Dark Matter  

CERN Document Server

Supersymmetry, a new symmetry that relates bosons and fermions in particle physics, still escapes observation. Search for SUSY is one of the main aims of the recently launched Large Hadron Collider. The other possible manifestation of SUSY is the Dark Matter in the Universe. The present lectures contain a brief introduction to supersymmetry in particle physics. The main notions of supersymmetry are introduced. The supersymmetric extension of the Standard Model - the Minimal Supersymmetric Standard Model - is considered in more detail. Phenomenological features of the MSSM as well as possible experimental signatures of SUSY at the LHC are described. The DM problem and its possible SUSY solution is presented.

2010-01-01

173

Study of somatic radiation effects in environment  

International Nuclear Information System (INIS)

A survey is presented of the consequences of the irradiation of the population with ionizing radiation. There is an increased incidence of leukemia in irradiated population groups. Among the inhabitants of Hiroshima and Nagasaki maximum death of leukemia was observed in the years 1951 to 1952. The results are summed up of the observation of carcinoma of the breast, lungs and bronchi, bones, and carcinoma of the thyroid. The effect of radiation on experimental animals is described. It was found that the scatter of the dependence of the incidence of various types of cancer on the dose equivalent apparently reflects differences in the biological mechanism of this incidence and that a proportional relationship cannot be expected between the primary damage of cells during irradiation and the actual manifestation of the disease. (E.S.).

174

Structural origin of optical bowing in semiconductor alloys p  

Energy Technology Data Exchange (ETDEWEB)

The principle of conservation and transferability of chemical bonds explains the recent discovery by extended x-ray absorption fine-structure measurements of two unequal anion-cation bond lengths R/sub A/C and R/sub B/C in A/sub x/B/sub 1-x/C zinc-blende semiconductor alloys despite the close adherence of the lattice constant to the average value (Vegard rule). This bond alternation, manifested as a structural distortion to a local chalcopyrite coordination around the anions, explains also most of the observed optical bowing in semiconductor alloys.

1983-08-22

175

Structural origin of optical bowing in semiconductor alloys p  

International Nuclear Information System (INIS)

The principle of conservation and transferability of chemical bonds explains the recent discovery by extended x-ray absorption fine-structure measurements of two unequal anion-cation bond lengths R/sub A/C and R/sub B/C in A/sub x/B/sub 1-x/C zinc-blende semiconductor alloys despite the close adherence of the lattice constant to the average value (Vegard rule). This bond alternation, manifested as a structural distortion to a local chalcopyrite coordination around the anions, explains also most of the observed optical bowing in semiconductor alloys.

176

On the mechanism of the nonmonotonic relaxation processes in the metallic melts  

International Nuclear Information System (INIS)

The numerical analysis of the experimental data on viscosity change by time in the period after fast heating and crystal-liquid phase transition for the copper nonequilibrium melts and the Fe_7_0Cr_1_0P_1_3C_7 glass-forming melt near their melting temperatures is accomplished through the method of correlation functions and the Rytov-Dimentberg criterion. The observed dependences have nonmonotonic oscillating character but they do not relate to auto-oscillations. The proposed theoretical model of the properties oscillations origination by relaxation in the nonequilibrium liquids explains them as manifestation of noise-induced transitions in the metastable area near the critical temperatures (melting, structural transitions)

2000-01-01

177

Multiquark in high-energy nuclear processes  

International Nuclear Information System (INIS)

The constants, applied in the phenomenological approaches for describing the nuclear reactions with the high transmitted pulse, are obtained within the frames of the multiquark flucton microscopic model. The constants values prove to be universal for all the nuclei and independent on the collision energy and flucton properties (excluding its mass), i.e. the peculiar scaling is manifested in the reaction cross sections. The theoretically obtained values of these constants are in good agreement with the phenomenological values, derived from the (p, p'X) reaction cross sections on the nuclei for X=d, t, "3He

2004-11-01

178

Molecular dynamics study of reaction kinetics in viscous media  

British Library Electronic Table of Contents (United Kingdom)

Predicted by stochastic models and observed experimentally in a number of isomerization reactions, viscosity-induced solvent effects manifest themselves in a significant departure of the reaction rates from the values expected on the basis of transition state theory. These effects are well understood within the framework of stochastic models; however, the predictive power of such models is limited by the fact that their parameters are not readily available. Experiment and molecular dynamics (MD) simulations can provide such information and can serve as the testing grounds for various stochastic models. In real solvents, a change in viscosity is inevitably associated with variation of at least one of the three factors - temperature, pressure, or solvent identity, resulting in different solv...

2011-01-01

179

Manifestation of isotope effects in absorption spectra of "1"4"4Sm"3"+ and "1"5"4Sm"3"+ in solutions  

International Nuclear Information System (INIS)

Photoluminescence spectra for solutions containing Sm"3"+ isotope ions in heavy and normal water were studied in the wave length #lambda# = 500-700 nm and for absorption spectra and photoluminescence excitation spectra within the range of #lambda# = 260-600 nm. Differences in molar extinction coefficients for "1"4"4Sm"3"+ and "1"5"4Sm"3"+ were established both in the solutions with D_2O and by transition from the solutions with D_2O to the solutions with H_2O. New possible causes of the identified effects are discussed

1998-01-01

180

Light Scalar Mesons as Manifestation of Spontaneously Broken Chiral Symmetry  

CERN Document Server

Attention is paid to the production mechanisms of light scalars that reveal their nature. We reveal the chiral shielding of the \\sigma(600) meson. We show that the kaon loop mechanism of the \\phi radiative decays, ratified by experiment, points to the four-quark nature of light scalars. We show also that the light scalars are produced in the two photon collisions via four-quark transitions in contrast to the classic P wave tensor q\\bar q mesons that are produced via two-quark transitions $\\gamma\\gamma\\to q\\bar q$. The history of spontaneous breaking of symmetry in quantum physics is discussed in Appendix.

2010-01-01

181

Influence of scattering on superluminescence in composites dye solution ? nanoparticles  

British Library Electronic Table of Contents (United Kingdom)

Spectral and energy luminescence characteristics of R6G dye solutions in ethanol with addition of Ag nanoparticle suspensions in different aggregate states are experimentally investigated. It is demonstrated that incorporation of non-aggregated and aggregated nanoparticles causes the superluminescence thresholds in R6G solutions to decrease. It is established that the optical properties of the laser beam propagation channel are transformed when low-power (20?mW) cw laser radiation passes through the suspension of nanoparticles. This is manifested through the occurrence of a region with enhanced nanoparticle density in the laser beam center, on which diffraction of laser radiation is observed.

2011-01-01

182

Influence of scattering on superluminescence in composites dye solution - nanoparticles  

Science.gov (United States)

Spectral and energy luminescence characteristics of R6G dye solutions in ethanol with addition of Ag nanoparticle suspensions in different aggregate states are experimentally investigated. It is demonstrated that incorporation of non-aggregated and aggregated nanoparticles causes the superluminescence thresholds in R6G solutions to decrease. It is established that the optical properties of the laser beam propagation channel are transformed when low-power (20 mW) cw laser radiation passes through the suspension of nanoparticles. This is manifested through the occurrence of a region with enhanced nanoparticle density in the laser beam center, on which diffraction of laser radiation is observed.

2011-09-01

183

Infinite-parametric extension of the conformal algebra in D>2 space-time dimensions  

International Nuclear Information System (INIS)

On the basis of the analytic continuations of semisimple Lie algebras discovered recently by us we construct manifestly quasiconformal infinite-dimensional algebras AC(so(4, 1)) and PAC(so(3, 2)) extending the conformal algebras in three-dimensional euclidean and Minkowski space-time like the Virasoro algebra extends so(2, 1). Their higher spin generalizations are also constructed. A counterpart of the central extension for D > 2 and possible appplications in exactly solvable conformal quantum field models in D > 2 are discussed. (orig.).

1991-01-01

184

Imaging findings of abdominal peripheral primitive neuroectodermal tumor: report of four cases with pathological correlation  

British Library Electronic Table of Contents (United Kingdom)

Peripheral primitive neuroectodermal tumors (peripheral PNETs) are rare in the abdomen. We report the imaging findings of four peripheral PNETs arising in the abdomen. Three were ill-demarcated tumors and one was a well-demarcated tumor, with extensive local invasion and lymph node metastasis in two cases, respectively. The tumors are of inhomogeneous attenuation and heterogeneous enhancement after intravenous administration of contrast materials. Although their imaging manifestations cannot distinguish them from other sarcomas, recognition of these imaging features may be helpful in suggesting the possibility of peripheral PNETs in some cases.

2009-01-01

185

Home shrines in Britain and associated spiritual values  

British Library Electronic Table of Contents (United Kingdom)

In a quantitative survey of religious attitudes and practices in a multi-religious sample of 369 school pupils aged between 13 and 15 in London, the presence of a home shrine was found widespread in 11% of adolescents spanning several religious affiliations and ethnicities - especially Buddhists, Hindus and those of Indian, Chinese and 'Other Asian' ethnicity. Having a home shrine correlated significantly with spiritual attitudes such as agreement with filial piety, the Eightfold Path, subjectivity of happiness, meditation, Sikh festivals, reincarnation and opening Gurdwaras to all. It is suggested that teachers and the social services should be aware of the importance of shrines to many religious communities and recognise their potential as a spiritual asset and manifestation of religion ...

2010-01-01

186

Effective numbers of multiquark fluctons in nuclei  

Energy Technology Data Exchange (ETDEWEB)

A technique for calculation of the total weight of quark clusters-fluctons: in nuclei is developed. Blokhintsev's formula is justified microscopically and refined by introduction of spin-charge and quark factors. It is shown that the large values of the correlation radius (R/sub C/approx. =0.75 fm or 1.0 fm) derived from experimental data in various papers using this formula correspond to )similarreverse arrowto)2.5 times smaller internucleon distances in the flucton (0.3--0.4 fm), i.e., the hardness of fluctons is caused by unsuppressed manifestation of hidden color at such distances (the corresponding probabilities are presented)

1987-08-01

187

Effective numbers of multiquark fluctons in nuclei  

International Nuclear Information System (INIS)

A technique for calculation of the total weight of quark clusters-fluctons: in nuclei is developed. Blokhintsev's formula is justified microscopically and refined by introduction of spin-charge and quark factors. It is shown that the large values of the correlation radius (R/sub C/#approx =#0.75 fm or 1.0 fm) derived from experimental data in various papers using this formula correspond to #left brace#similarreverse arrowto#right brace#2.5 times smaller internucleon distances in the flucton (0.3--0.4 fm), i.e., the hardness of fluctons is caused by unsuppressed manifestation of hidden color at such distances (the corresponding probabilities are presented).

188

D-brane probe and closed string tachyons  

International Nuclear Information System (INIS)

We consider a D-brane probe in the unstable string background associated with flux branes. The twist in the spacetime metric reponsible for supersymmetry breaking is shown to manifest itself in the mixing of open Wilson lines with the phases of some adjoint matter fields, resulting in a nonlocal and nonsupersymmetric form of Yang-Mills theory as the probe dynamics. This provides a setup where one can study the fate of a large class of unstable closed string theories that includes as a limit type 0 theories and various orbifolds of type II and type 0 theories. We discuss the limit of C/Z_n orbifold in some detail and speculate on the couplings with closed string tachyons.

2002-04-15

189

Constraints on extra dimensions from cosmological and terrestrial measurements  

CERN Document Server

If quantum fields exist in extra compact dimensions, they will give rise to a quantum vacuum or Casimir energy. That vacuum energy will manifest itself as a cosmological constant. The fact that supernova and cosmic microwave background data indicate that the cosmological constant is of the same order as the critical mass density to close the universe supplies a lower bound on the size of the extra dimensions. Recent laboratory constraints on deviations from Newton's law place an upper limit. The allowed region is so small as to suggest that either extra compact dimensions do not exist, or their number is about to be tightly constrained by experimental data.

2001-01-01

190

Constraints on Extra Dimensions from Cosmological and Terrestrial Measurements  

CERN Document Server

If quantum fields exist in extra compact dimensions, they will give rise to a quantum vacuum or Casimir energy. That vacuum energy will manifest itself as a cosmological constant. The fact that supernova and cosmic microwave background data indicate that the cosmological constant is of the same order as the critical mass density to close the universe supplies a lower bound on the size of the extra dimensions. Recent laboratory constraints on deviations from Newton's law place an upper limit. The allowed region is so small as to suggest that either extra compact dimensions do not exist, or their properties are about to be tightly constrained by experimental data.

2000-01-01

191

All Optical Switch of Vacuum Rabi Oscillations: The Ultrafast Quantum Eraser  

CERN Document Server

We study the all-optical time-control of the strong coupling between a single cascade three-level quantum emitter and a microcavity. We find that only specific arrival-times of the control pulses succeed in switching-off the Rabi oscillations. Depending on the arrival times of control pulses, a variety of exotic non-adiabatic cavity quantum electrodynamics effects can be observed. We show that only control pulses with specific arrival times are able to suddenly switch-off and -on first-order coherence of cavity photons, without affecting their strong coupling population dynamics. Such behavior may be understood as a manifestation of quantum complementarity.

2010-01-01

192

Acquired cystic kidney disease  

Energy Technology Data Exchange (ETDEWEB)

Acquired cystic kidney disease (ACKD), also known as acquired renal cystic disease (ARCD,) occurs in patients who are on dialysis for end-stage renal disease. It is generally accepted that ACKD develops as a consequence of sustained uremia and can first manifest even before dialysis is initiated while the patient is still in chronic renal failure. The role of immune suppression, particularly in transplant recipients, in the development of ACKD, is still under investigation. The prevalence of ACKD is directly related to the duration of dialysis and the risk of cancer is directly related to the presence of cysts. Herein we review the current understanding of the pathophysiology and imaging implications of ACKD. (orig.)

2000-11-01

193

A viable model of locally anisotropic space-time and the Finslerian generalization of the relativity theory  

Energy Technology Data Exchange (ETDEWEB)

The work is devoted to the construction of a viable of locally anisotropic, i.e. Finslerian, space-time and to the generalization, on this basis, of the relativistic theory of gravitation. Arguments in favour of this model are considered. From physical considerations the concrete form of the Finslerian metric has been reconstructed and within the framework of the correspondence principle a formalism of the theory has been developed. The approach suggested is aimed at developing unified gauge theories of all fundamental interactions. Much attention is given to the nontrivial physical manifestations of local space anisotropy and to the possibility of its experimental detection. (orig.)

1994-01-01

194

Variation in the Definition of Clinical Target Volumes for Pelvic Nodal Conformal Radiation Therapy for Prostate Cancer  

UK PubMed Central (United Kingdom)

PurposeWe conducted a comparative study of Clinical Target Volume (CTV) definition of pelvic lymph nodes by multiple GU radiation oncologists looking at the levels...Full Text Available

2009-06-01

195

Toxic Myopathy in a Dog Associated with the Presence of Monensin in Dry Food  

UK PubMed Central (United Kingdom)

This report describes a case of toxic myopathy in a two year old sheltie dog with clinical signs of profound weakness, myoglobinuria, and muscle enzyme elevations. The clinical signs were likely related...Full Text Available

1980-01-01

196

The Clinical Value of PET with Amino Acid Tracers for Gliomas WHO Grade II  

UK PubMed Central (United Kingdom)

The clinical management of adults with low-grade gliomas (LGGs) remains a challenge. There is no curative treatment, and management of individual patients is a matter of deciding optimal timing as well...Full Text Available

2011-01-01

197

The Abandoned Radical Hysterectomy for Cervical Cancer: Clinical Predictors and Outcomes  

UK PubMed Central (United Kingdom)

Objective. Cervical cancer patients who had an abandoned radical hysterectomy were evaluated for preoperative clinical predictors, complication rates, and outcomes. Study...Full Text Available

2010-01-01

198

Stopping or Reporting Early for Positive Results in Randomized Clinical Trials: The National Cancer Institute Cooperative Group Experience From 1990 to 2005  

UK PubMed Central (United Kingdom)

Randomized clinical trials are designed with stopping boundaries to guide data monitoring committees with their decision making concerning ongoing trials. In particular, when extremely positive results...Full Text Available

2009-04-01

199

Sex, Gender, and Pain: A Review of Recent Clinical and Experimental Findings  

UK PubMed Central (United Kingdom)

Sex-related influences on pain and analgesia have become a topic of tremendous scientific and clinical interest, especially in the last 10 to 15 years. Members of our research group published...Full Text Available

2009-05-01

200

SNQ for medical research  

Energy Technology Data Exchange (ETDEWEB)

The planned spallation source can be of considerable significance for biomedical basic research and for clinically relevant diagnostic and therapeutic applications. The following gives a brief description and explanations for its possible use in clinical medicine: I. Treatment of Malignant Tumors II. Production of Isotopes for Biochemical Investigations in Living Organisms for Diagnostic Purposes.

1984-12-01

201

Relationship Between Exposure, Clinical Malaria, and Age in an Area of Changing Transmission Intensity  

UK PubMed Central (United Kingdom)

The relationship between malaria transmission intensity and clinical disease is important for predicting the outcome of control measures that reduce transmission. Comparisons of hospital data...Full Text Available

2008-08-01

202

Radionuclide imaging of the acutely painful scrotum  

International Nuclear Information System (INIS)

This paper discusses the clinical application and main objective of testicular imaging. The authors present cases that represent a spectrum of the abnormalities which might be detected by testicular imaging, with special attention given to testicular torsion and the acute diseases which may mimic it clinically. Accuracy of the test is noted.

203

Quantities and types of ceramides and their relationships to physical properties of the horn covering the claws of clinically normal cows and cows with subclinical laminitis  

UK PubMed Central (United Kingdom)

AbstractQuantities and types of ceramides and their relationships to physical properties of the horn covering the claws of clinically normal cows and cows with subclinical laminitis were...Full Text Available

2005-04-01

204

Protecting clinical data on Web client computers: the PCASSO approach.  

UK PubMed Central (United Kingdom)

The ubiquity and ease of use of the Web have made it an increasingly popular medium for communication of health-related information. Web interfaces to commercially available clinical information systems...Full Text Available

1998-01-01

205

Percutaneous endoscopic lumbar discectomy: clinical and quality of life outcomes with a minimum 2 year follow-up  

UK PubMed Central (United Kingdom)

BackgroundPercutaneous endoscopic lumbar discectomy is a relatively new technique. Very few studies have reported the clinical outcome of percutaneous endoscopic discectomy in terms...Full Text Available

206

Paying for treatments? Influences on negotiating clinical need and decision-making for dental implant treatment  

UK PubMed Central (United Kingdom)

BackgroundThe aim of this study is to examine how clinicians and patients negotiate clinical need and treatment decisions within a context of finite resources. Dental implant treatment...Full Text Available

207

Oncology data management in the UK--BODMA's view. British Oncology Data Managers Association.  

UK PubMed Central (United Kingdom)

Over the past 10 years, the original partnership of clinician and statistician for the running of clinical research projects, especially clinical trials, has come to be supplemented by the data manager...Full Text Available

1994-09-01

208

Novel therapies for resistant focal segmental glomerulosclerosis (FONT) phase II clinical trial: study design  

UK PubMed Central (United Kingdom)

BackgroundThe lack of adequate randomized clinical trials (RCT) has hindered identification of new therapies that are safe and effective for patients with primary focal segmental...Full Text Available

209

No Effect of a Homeopathic Preparation on Neonatal Calf Diarrhoea in a Randomised Double-Blind, Placebo-Controlled Clinical Trial  

UK PubMed Central (United Kingdom)

A double-blind, placebo-controlled clinical trial of a homeopathic treatment of neonatal calf diarrhoea was performed using 44 calves in 12 dairy herds. Calves with spontaneously derived diarrhoea were...Full Text Available

2003-01-01

210

Molecular characterization of hepatitis A virus isolates from environmental and clinical samples in Greece  

UK PubMed Central (United Kingdom)

BackgroundHepatitis A virus (HAV) strains detected in environmental and clinical samples were analysed to characterize the genotypes of HAV circulating in Greece. Fifty (50) sewage...Full Text Available

211

McMaster PLUS: A Cluster Randomized Clinical Trial of an Intervention to Accelerate Clinical Use of Evidence-based Information from Digital Libraries  

UK PubMed Central (United Kingdom)

BackgroundPhysicians have difficulty keeping up with new evidence from medical research.MethodsWe developed the McMaster Premium...Full Text Available

2006-11-01

212

Integrating Query of Relational and Textual Data in Clinical Databases: A Case Study  

UK PubMed Central (United Kingdom)

Objectives: The authors designed and implemented a clinical data mart composed of an integrated information retrieval (IR) and relational database management system (RDBMS).Design:...Full Text Available

2003-01-01

213

Implementation and use of a web-based interface for confidential communication of data between the clinical and research environments  

UK PubMed Central (United Kingdom)

Policies and regulations in the current health care environment have impacted the manner in which patient data - especially protected health information (PHI) - are handled in the clinical and...Full Text Available

2008-02-20

214

Impact of the Metabolic Syndrome on the Clinical Outcome of Patients with Acute ST-Elevation Myocardial Infarction  

UK PubMed Central (United Kingdom)

We sought to determine the prevalence of metabolic syndrome (MS) in patients with acute myocardial infarction and its effect on clinical outcomes. Employing data from the Korea Acute Myocardial Infarction...Full Text Available

2010-10-01

215

Impact of Electronic Health Record Clinical Decision Support on Diabetes Care: A Randomized Trial  

UK PubMed Central (United Kingdom)

PURPOSE We wanted to assess the impact of an electronic health record–based diabetes clinical decision support system on control of hemoglobin A1c (glycated hemoglobin),...Full Text Available

2011-01-01

216

Impact of Clinical Oral Chemotherapy Program on Wastage and Hospitalizations  

UK PubMed Central (United Kingdom)

Purpose:The oral chemotherapy cycle management program (CMP) provides clinical management support to patients receiving certain oral chemotherapies. The CMP includes a dose-monitoring...Full Text Available

2011-05-01

217

Imaging of membranous dysmenorrhea  

Energy Technology Data Exchange (ETDEWEB)

Membranous dysmenorrhea is an unusual clinical entity. It is characterized by the expulsion of huge fragments of endometrium during the menses, favored by hormonal abnormality or drug intake. This report describes a case with clinical, US, and MRI findings before the expulsion. Differential diagnoses are discussed. (orig.)

2001-06-01

218

How can information extraction ease formalizing treatment processes in clinical practice guidelines? A method and its evaluation?  

UK PubMed Central (United Kingdom)

SummaryObjective:Formalizing clinical practice guidelines (CPGs) for a subsequent computer-supported processing is a challenging, but burdensome and...Full Text Available

2007-02-01

219

HEARTVIEW-A Knowledge Base to Support Clinical Research in Cardiology  

UK PubMed Central (United Kingdom)

This paper presents HEARTVIEW - a knowledge base (KB) that offers aid for clinical research in cardiology. This KB is an essential component of the medical workstation MW2000, now under development...Full Text Available

1990-11-07

220

Growth-Phase-Dependent Expression of Virulence Factors in an M1T1 Clinical Isolate of Streptococcus pyogenes  

UK PubMed Central (United Kingdom)

The effect of growth phase on expression of virulence-associated factors was studied by Northern hybridization in an M1T1 clinical isolate of Streptococcus pyogenes. Expression of M...Full Text Available

1999-10-01

221

Gardnerella vaginalis: characteristics, clinical considerations, and controversies.  

UK PubMed Central (United Kingdom)

The clinical significance, Gram stain reaction, and genus affiliation of Gardnerella vaginalis have been controversial since Gardner and Dukes described the organism as the cause of "nonspecific vaginitis,"...Full Text Available

1992-07-01

222

Endovascular covered stenting for the management of post-percutaneous nephrolithotomy renal pseudoaneurysm: a case report  

UK PubMed Central (United Kingdom)

IntroductionIntrarenal pseudoaneurysm is a rare, yet clinically significant, complication of percutaneous nephrolithotomy. A high index of clinical suspicion is necessary in order...Full Text Available

223

Effect of Peroxisome Proliferator-Activated Receptor Gamma Agonist (Pioglitazone) and Methotrexate on Disease Activity in Rheumatoid Arthritis (Experimental and Clinical Study)  

UK PubMed Central (United Kingdom)

Objective:To investigate the combined effect of both pioglitazone and methotrexate on disease activity of rheumatoid arthritis in a biphasic study; experimental and clinical.Methods:Experimentally:...Full Text Available

224

Dissemination of the published results of an important clinical trial: an analysis of the citing literature.  

UK PubMed Central (United Kingdom)

The definitive clinical trial which demonstrated the beneficial effects of photocoagulation in treating diabetic retinopathy was reported in 1976 in the American Journal of Ophthalmology by the Diabetic...Full Text Available

1981-07-01

225

Detection and Differentiation of Cryptosporidium spp. in Human Clinical Samples by Use of Real-Time PCR?  

UK PubMed Central (United Kingdom)

Real-time PCR has the potential to streamline detection and identification of Cryptosporidium spp. in human clinical samples. In the present...Full Text Available

2011-03-01

226

Coryneform bacteria in infectious diseases: clinical and laboratory aspects.  

UK PubMed Central (United Kingdom)

Coryneform isolates from clinical specimens frequently cannot be identified by either reference laboratories or research laboratories. Many of these organisms are skin flora that belong to a large number...Full Text Available

1990-07-01

227

Coracoid pain test: a new clinical sign of shoulder adhesive capsulitis  

UK PubMed Central (United Kingdom)

Patients with adhesive capsulitis were clinically evaluated to establish whether pain elicited by pressure on the coracoid area may be considered a pathognomonic sign of this condition. The study group...Full Text Available

2010-03-01

228

Composition, Stability, and Bioavailability of Garlic Products Being Used in a Clinical Trial  

UK PubMed Central (United Kingdom)

In support of a new clinical trial designed to compare the effects of crushed fresh garlic and two types of garlic supplement tablets (enteric-coated dried fresh garlic and dried aged garlic...Full Text Available

2005-08-10

229

Clinical-HINTS: integrated intelligent ICU patient monitoring and information management system.  

Science.gov (United States)

Clinical-HINTS (Health Intelligence System) is a horizontally integrated decision support system (DSS) designed to meet the requirements for intelligent real-time clinical information management in critical care medical environments and to lay the foundation for the development of the next generation of intelligent medical instrumentation. The system presented was developed to refine and complement the information yielded by clinical laboratory investigations, thereby benefiting the management of the intensive care unit (ICU) patient. More specifically, Clinical-HINTS was developed to provide computer-based assistance with the acquisition, organisation and display, storage and retrieval, communication and generation of real-time patient-specific clinical information in an ICU. Clinical-HINTS is an object-oriented system developed in C+2 to run under Microsoft ...

1997-01-01

230

Clinical value of SPECT/CT for evaluation of patients with painful knees after total knee arthroplasty- a new dimension of diagnostics?  

UK PubMed Central (United Kingdom)

BackgroundThe purpose of our study was to evaluate the clinical value of hybrid SPECT/CT for the assessment of patients with painful total knee arthroplasty (TKA).MethodsTwenty-three...Full Text Available

231

Clinical pathology accreditation: standards for the medical laboratory  

UK PubMed Central (United Kingdom)

This article describes a new set of revised standards for the medical laboratory, which have been produced by Clinical Pathology Accreditation (UK) Ltd (CPA). The original standards have been in use...Full Text Available

2002-10-01

232

Clinical and laboratory studies in patients with leprosy and enthesitis.  

UK PubMed Central (United Kingdom)

In a combined clinical, radiological, and laboratory study of 77 patients throughout the leprosy spectrum, 10 patients had an enthesitis which has not been described previously as far as is known and...Full Text Available

1990-09-01

233

Clinical Significance of the Detection of Antinuclear Antibodies in Patients with Acute Hepatitis A  

UK PubMed Central (United Kingdom)

Background/AimsThe findings of several recent studies suggest that antinuclear antibodies (ANAs) are frequently detected in patients with acute hepatitis A (AHA). However, the clinical...Full Text Available

2011-09-01

234

Clinical Implications of Immunohistochemically Demonstrated Lymph Node Micrometastasis in Resectable Pancreatic Cancer  

UK PubMed Central (United Kingdom)

The purpose of this study was to determine the clinical significance of nodal micrometastasis detected by immunohistochemistry in patients that had undergone curative surgery for pancreatic cancer....Full Text Available

2011-07-01

235

Clinical Features and Treatments of Upper Lumbar Disc Herniations  

UK PubMed Central (United Kingdom)

ObjectiveDisc herniations at the L1-L2 and L2-L3 levels are different from those at lower levels of the lumbar spine with regard to clinical characteristics and surgical outcome....Full Text Available

2010-08-01

236

Clinical Characteristics and Treatment Outcome of Depression in Patients with and without a History of Emotional and Physical Abuse  

UK PubMed Central (United Kingdom)

Clinical features and treatment outcome were compared in depressed outpatients with and without a history of emotional and physical abuse (EPA), including childhood maltreatment. Patients were...Full Text Available

2010-04-01

237

Chlamydial urethral infection in Teheran. A study of male patients attending an STD clinic.  

UK PubMed Central (United Kingdom)

The prevalence of chlamydial infection of the urethra was studied in 172 consecutive male patients attending a sexually transmitted disease clinic in Teheran. Chlamydia trachomatis was isolated in 8.8%...Full Text Available

1982-12-01

238

Carcinoma Metastatic to Both Cerebellopontine Angles Masquerading as Acoustic Neuromas  

UK PubMed Central (United Kingdom)

Metastases to the cerebellopontine angles (CPAs) are rare. Typically, the clinical course is one of rapid onset and progression of crarial nerve deficits. The clinical presentation and course of carcinoma...Full Text Available

1995-01-01

239

Automated Creation of Datamarts from a Clinical Data Warehouse, Driven by an Active Metadata Repository  

UK PubMed Central (United Kingdom)

A methodology and toolkit are described which enable the automated metadata-driven creation of datamarts from clinical data warehouses. The software uses schema-to-schema transformation driven by an...Full Text Available

1998-01-01

240

Association of serum markers with improvement in clinical response measures after treatment with golimumab in patients with active rheumatoid arthritis despite receiving methotrexate: results from the GO-FORWARD study  

UK PubMed Central (United Kingdom)

IntroductionThe goal of this study was to identify serum markers that are modulated by treatment with golimumab with or without methotrexate (MTX) and are associated with clinical...Full Text Available

2010-01-01

241

Association of elevated levels of extracellular neuraminidase with clinical isolates of type III group B streptococci.  

UK PubMed Central (United Kingdom)

The level of total extracellular neuraminidase produced by 74 clinical isolates of group B streptococci isolated from diseased or asymptomatically colonized infants was assayed. Extracellular neuraminidase...Full Text Available

1978-09-01

242

Analysis of clinical records of dental patients attending Jordan University Hospital: Documentation of drug prescriptions and local anesthetic injections  

UK PubMed Central (United Kingdom)

Objectives:The aim of this study was to analyze clinical records of dental patients attending the Dental Department at the University of Jordan Hospital: a teaching hospital in Jordan....Full Text Available

2008-10-01

243

Addressing the Question of the Effect of RBC Storage on Clinical Outcomes: The Red Cell Storage Duration Study (RECESS) (Section 7)  

UK PubMed Central (United Kingdom)

The question of whether storage of red blood cells (RBCs) alters their capacity to deliver oxygen and affects patient outcomes remains in a state of clinical equipoise. Studies of the changes...Full Text Available

2010-08-01

244

Acute kidney injury in the intensive care unit: current trends in incidence and outcome  

UK PubMed Central (United Kingdom)

Acute kidney injury (AKI) is a common clinical problem with significant clinical and economic consequences. A number of studies point to a rising incidence of AKI in the hospital and in the intensive...Full Text Available

2007-01-01

245

Accuracy of Contacts Calculated from 3D Images of Occlusal Surfaces  

UK PubMed Central (United Kingdom)

ObjectiveCompare occlusal contacts calculated from 3D virtual models created from clinical records to contacts identified clinically using shimstock and transillumination.Full Text Available

2007-06-01

246

A Wireless Health Outcomes Monitoring System (WHOMS): development and field testing with cancer patients using mobile phones  

UK PubMed Central (United Kingdom)

BackgroundHealth-Related Quality of Life assessment is widely used in clinical research, but rarely in clinical practice. Barriers including practical difficulties administering...Full Text Available

247

A Web-based Interface for Communication of Data between the Clinical and Research Environments without Revealing Identifying Information  

UK PubMed Central (United Kingdom)

Recent health care policies and regulations have impacted the manner in which patient data – especially protected health information (PHI) – are handled in both the clinical...Full Text Available

2007-06-01

248

A System for the Recording of Clinical Data as an Aid in the Diagnosis of Bovine Digital Disease  

UK PubMed Central (United Kingdom)

A form for the clinical evaluation of bovine digital disease was developed. In this article, each section of the resulting Digit Evaluation Form is discussed and justified. By following the...Full Text Available

1986-08-01

249

A Pragmatic Approach to Implementing Best Practices for Clinical Decision Support Systems in Computerized Provider Order Entry Systems  

UK PubMed Central (United Kingdom)

Incorporation of clinical decision support (CDS) capabilities is required to realize the greatest benefits from computerized provider order entry (CPOE) systems. Discussions at a conference on CDS in...Full Text Available

2007-01-01

250

Quality assurance requirements in a clinical heavy ion therapy unit  

International Nuclear Information System (INIS)

German 2006 [1 p.] Germany Karger, Christian Heeg, Peter Jaekel, Oliver

2006-03-13

254

Bacterial conjunctivitis  

UK PubMed Central (United Kingdom)

Clinical questionWhat is the best treatment for bacterial conjunctivitis?ResultsTopical antibiotics expedite recovery from bacterial conjunctivitis....Full Text Available

2010-01-01

255

Hazardous-waste disposal and the clinical laboratory. Final report, May-December 1989  

Energy Technology Data Exchange (ETDEWEB)

Negligent hazardous waste management has resulted in real threats to public health. The Federal Government has responded to the situation with laws and regulations aimed at the producers of hazardous waste, including clinical laboratories. The Resources Conservation and Recovery Act (RCRA) imposes controls on hazardous waste management through the Code of Federal Regulations (CFR). The Environmental Protection Agency (EPA) and the Department of Transportation (DOT) regulate these activities through 40 CFR and 49 CFR. Most clinical laboratories can operate satellite accumulation points and accumulate, store, transport, and dispose of waste in accordance with EPA and DOT regulations. Regulations pertaining to infectious waste, sure to affect many clinical laboratories, are being developed now by he EPA. The cradle to grave tracking system mandated by the Federal Government can be supplemented by state and local authorities ...

1990-01-01

256

Clinical outcomes and risk factors for technical and clinical failures of self-expandable metal stent insertion for malignant colorectal obstruction  

British Library Electronic Table of Contents (United Kingdom)

BackgroundAlthough self-expandable metal stent (SEMS) insertion is widely used for relief of malignant colorectal obstructions, the immediate technical and clinical failure rates of SEMSs and the associated risk factors remain largely unknown. ObjectiveTo identify rates and factors predictive of technical and clinical failure of SEMSs when their use is attempted for the decompression of malignant colorectal obstruction. DesignRetrospective chart review. SettingA tertiary-care academic medical center in South Korea. PatientsThis study involved a total of 412 patients with malignant colorectal obstruction in whom SEMS insertion was attempted. InterventionPlacement of colonic SEMSs. Main Outcome MeasurementsTechnical success and immediate and long-term clinical success rates. ResultsTechnical...

2011-01-01

257

The implications of tolerance system interpretation on past and present dimensional variability studies  

Energy Technology Data Exchange (ETDEWEB)

Dimensional variability studies and published dimensional variability standards have been used by the foundry industry for years as an indicator of the casting process` ability to produce uniform parts. These studies are an extremely useful tool in the continuous ``dimensional dialogue`` between foundries and customers. The nature of these studies, and of the current tolerancing systems used by casting designers, leaves room for some misinterpretation and misuse of these study results. This paper contains two important discussions. The first part explains exactly what these studies represent. Following this is a brief explanation on dimensional and geometric tolerances and how they communicate dimensional requirements.

1994-12-31

258

Man-made disasters: A cross-national analysis  

British Library Electronic Table of Contents (United Kingdom)

This research investigates the impact of national culture and several institutional factors on the safety performance of society and establishes statistically significant relationships between those variables. As expected, the research results reveal that some cultural variables such as uncertainty avoidance, gender orientation and institutional variables such as the degree of law avoidance can directly influence the safety performance of the society. The findings also support the inverted u-curve (Safety Kuznet curve) hypothesis indicating even if we expect a negative trend at the beginning stage of industrialization, we can expect a positive trend in safety performance as their income level continues to improve beyond a certain point.

2011-01-01

259

Go vs. no-go - potential and limitations of continuous-variable quantum computing by measurements  

Energy Technology Data Exchange (ETDEWEB)

In this talk, we explore the feasibility of quantum computation using continuous-variable systems by means of local measurements only. In the first part of the talk, we will identify crucial limitations that arise when starting from Gaussian cluster states. This is done by resorting to a Gaussian projected entangled pair picture as well as to notions of continuous-variable quantum repeater networks. In the second part, we look at instances in which these limitations can be overcome, and how suitable encodings of qubits in oscillators and feasible non-Gaussian resource states give rise to universal schemes for quantum computing.

2010-07-01

260

Creep properties of modified 9 Cr-1 Mo steel  

Energy Technology Data Exchange (ETDEWEB)

Creep properties of modified 9 Cr-1 Mo steel, an alloy significantly improved in elevated-temperature strength over 2 1/4 Cr-1 Mo and other similar alloys, are presented here. Data are primarily on material in the normalized and tempered condition. Effects of variables such as isothermal annealing treatment, cold work, normalizing temperature, tempering temperature, notch, and biaxial stress state have also been examined. Data analysis and comparisons have shown that modified 9 Cr-1 Mo alloy is very insensitive in response to several material variables, heat treatments, and specimen design variables.

1983-01-01

261

Vascular Effects of Photodynamic and Pulsed Dye Laser Therapy Protocols  

UK PubMed Central (United Kingdom)

Background and ObjectivePulsed dye laser (PDL) treatment of cutaneous vascular lesions is associated with variable and unpredictable efficacy. Thus, alternative treatment...Full Text Available

2008-11-01

262

Variability in Melanoma Metalloproteinase Expression Profiling  

UK PubMed Central (United Kingdom)

The proteolytic activities of a disintegrin and metalloproteinase (ADAM); a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS), and matrix metalloproteinase (MMP) families play important...Full Text Available

2010-12-01

263

The role of fatigue variability in life prediction of an #alpha#+#beta# titanium alloy  

International Nuclear Information System (INIS)

The fatigue life variability of the #alpha#+#beta# titanium alloy, Ti-6Al-2Sn-4Zr-6Mo increased with decreasing stress level. The variability in life was found to be due to segregation of lives due to two failure mechanisms. A bimodal cumulative distribution model was shown to accurately describe the combined failure modes. The nominal failure processes for the two regimes were similar, with crack nucleation occurring in equiaxed #alpha#p particles, irrespective of life or stress level. However the variability in life was not controlled by the size of the crack-nucleating #alpha#p, but rather by the ability of the material to distribute deformation and avoid early crack nucleation.

2004-06-10

264

Spatial and Temporal Variability of Column Integrated Aerosol - NASA  

Science.gov (United States)

the southern Arabian Gulf region left its signature on the heterogeneous aerosol .... Arabian Gulf region, since large differences in ? may be caused by ...

265

Spatial Variability of Wave Data from Todos Santos Bay, Baja California, Mexico  

Science.gov (United States)

... and operation of marine structures and to estimate coastal sediment transport. While the timely collection and report of high ... ...

266

Organismos que causan enfermedades transmitidas por los alimentos ...  

Science.gov (United States)

... Variable, Alimentos mal enlatados, especialmente verduras enlatadas en el hogar; pescado fermentado, papas asadas en papel de aluminio, ajo envasado. ...

267

Order in Spontaneous Behavior  

UK PubMed Central (United Kingdom)

Brains are usually described as input/output systems: they transform sensory input into motor output. However, the motor output of brains (behavior) is notoriously variable, even under identical sensory...Full Text Available

268

Optimization of extraction of high-ester pectin from passion fruit peel (Passiflora edulis flavicarpa) with citric acid by using response surface methodology  

British Library Electronic Table of Contents (United Kingdom)

A central composite design was employed to optimize the extraction of pectin with citric acid. The independent variables were citric acid concentration (0.086-2.91% w/v) and extraction time (17-102min). The combined effect of these variables on the degree of esterification was investigated. Results have shown that the generated regression models adequately explained the data variation and significantly represented the actual relationship between the independent variables and the responses. Besides that, the citric acid concentration was the most important factor to affect the degree of esterification, as it exerted a significant influence on the dependent variable. Lower citric acid concentration increased the pectin degree of esterification. The surface response showed the relationships b...

2008-01-01

269

Multifractal Analysis of Multiple Ergodic Averages  

CERN Document Server

In this paper we present a complete solution to the problem of multifractal analysis of multiple ergodic averages in the case of symbolic dynamics for functions of two variables depending on the first coordinate.

2011-01-01

270

Modeling hydrologic responses to deforestation/forestation and ...  

Science.gov (United States)

Worldwide century-long forest hydrologic research has documented that deforestation and forestation (i.e. reforestation and afforestation) can have variable ...

271

Koji Mukai's Bibliography - Astrophysics Science Division Staff ...  

Science.gov (United States)

Jul 25, 2011 ... Koji Mukai's Bibliography. Invited Reviews. Mukai, K. 1994, "ASCA PV Phase Observations of Cataclysmic Variables," in "New Horizon of X-ray ...

272

Fractal dynamics in physiology: Alterations with disease and aging  

UK PubMed Central (United Kingdom)

According to classical concepts of physiologic control, healthy systems are self-regulated to reduce variability and maintain physiologic constancy. Contrary to the predictions of homeostasis, however,...Full Text Available

2002-02-19

273

Floral ontogeny of Annonaceae: evidence for high variability in floral form  

UK PubMed Central (United Kingdom)

Background and AimsAnnonaceae are one of the largest families of Magnoliales. This study investigates the comparative floral development of 15 species to understand the basis for...Full Text Available

2010-10-01

274

Enhancement of bioleaching of a spent Ni/Mo hydroprocessing catalyst by Penicillium simplicissimum  

British Library Electronic Table of Contents (United Kingdom)

Statistically based experimental designs were applied to screen and optimize the bioleaching of spent hydrocracking catalyst by Penicillium simplicissimum. Eleven factors were examined for their significance on bioleaching using a Plackett-Burman factorial design. Four significant variables (pulp density, sucrose, NaNO"3, and yeast extract concentrations) were selected for the optimization studies. The combined effect of these variables on metal bioleaching was studied using a central composite design (CCD). Second-order polynomials were established to identify the relationship between the recovery percent of the metals and the four significant variables. The optimal values of the variables for maximum metals bioleaching were as follows: pulp density (4.0%, w/v), sucrose (90g/L), NaNO"3 (2...

2011-01-01

275

Effects of wildfires on environmental variability: a comparative analysis using different spectral indices, patch metrics and thematic resolutions  

British Library Electronic Table of Contents (United Kingdom)

Knowledge on environmental variability and how it is affected by disturbances is crucial for understanding patterns of biodiversity and determining adequate conservation strategies. The aim of this study is to assess environmental variability in patches undergoing post-fire vegetation recovery, identifying trends of change and their relevant drivers. We particularly evaluate: the value of three spectral indices derived from Landsat satellite data [Normalized Burn Ratio (NBR), Normalized Difference Vegetation Index (NDVI) and Wetness Component of the Tasseled Cap Transformation (TCW)] for describing secondary succession; the effectiveness of three metrics (diversity, evenness and richness) as indicators of patch variability; and how thematic resolution can affect the perception of environme...

2010-01-01

276

Effects of Climatic Variability and Land Use on American Drylands...  

Science.gov (United States)

Wildlife Refuge, CA Rare and endangered endemic plants Diana Anderson Northern Arizona University Geomorphology Kathryn Thomas USGS, Flagstaff, AZ Vegetation dynamics John...

2011-09-30

277

ENSO affects sex ratio progeny in captive Iberian red deer despite a steady feeding regime  

British Library Electronic Table of Contents (United Kingdom)

Climate variability greatly affects animals through direct and indirect effects. Animals with slow reproductive adaptation to ecological changes such as large mammals are likely to have evolved mechanisms to anticipate early such impacts of climate variability on the environment. One of the adaptive mechanisms between reproductive costs and benefits in mammals affects parental investment through biases in sex ratio. Deer might be likely to show an early detection of climate variability because conception takes place in early autumn, but the main raising cost in deer concerns lactation, which takes place at the end of the following spring. The aim of this paper is to assess whether there is a relationship between global indices of climate variability such as El Ni?o-Southern Oscillation (EN...

2011-01-01

278

DESIGN STUDY OF CONTINUOUSLY VARIABLE ROLLER CONE - NASA Technical ...  

Science.gov (United States)

pedel preo,ure. (_PD). VSO may be developed by nor_:el epeed-o-_eter means at the output. ,haft or it may be derived ...

279

Comparing Genomes within the Species Mycobacterium tuberculosis  

UK PubMed Central (United Kingdom)

The study of genetic variability within natural populations of pathogens may provide insight into their evolution and pathogenesis. We used a Mycobacterium tuberculosis high-density...Full Text Available

2001-04-01

280

Climate change/variability implications on hydroelectricity generation in the Zambezi River Basin  

British Library Electronic Table of Contents (United Kingdom)

The study has analysed the effects of various factors on hydroelectric power generation potential to include climate change/variability, water demand, and installation of proposed hydroelectric power schemes in the Zambezi River Basin. An assessment of historical (1970?2000) power potential in relation to climate change/variability at existing hydro electric power schemes(Cahora Bassa, Kariba, Kafue Gorge and Itezhi-Tezhi) in the Zambezi River Basin was conducted. The correlation of hydroelectric power potential with climate change/variability aimed at observing the link and extent of influence of the latter on the former was investigated. In order to predict the future outlook of hydro electric power potential, General Circulation Models (GCM) were used to generate projected precipitation...

2011-01-01

281

Characterizing partial upwellings ... - Lake Tahoe Validation - NASA  

Science.gov (United States)

measure meteorological variables and bulk water temper- ature. The locations of the buoys are given in Table 1. TB2 and TB3 were moved slightly farther south ...

282

Baxter Q-operator and Separation of Variables for the open SL(2,R) spin chain  

CERN Document Server

We construct the Baxter Q-operator and the representation of the Separated Variables (SoV) for the homogeneous open SL(2,R) spin chain. Applying the diagrammatical approach, we calculate Sklyanin's integration measure in the separated variables and obtain the solution to the spectral problem for the model in terms of the eigenvalues of the Q-operator. We show that the transition kernel to the SoV representation is factorized into the product of certain operators each depending on a single separated variable. As a consequence, it has a universal pyramid-like form that has been already observed for various quantum integrable models such as periodic Toda chain, closed SL(2,R) and SL(2,C) spin chains.

2003-01-01

283

Adaptive Pareto Set Estimation for Stochastic Mixed Variable ...  

Science.gov (United States)

... Direct Search (SMOMADS) and Paciencia's NMADS [45] based on Kim and de Weck's ... Todd Paciencia for his foundational contributions. ...

2009-03-01

284

A novel approach to the dynamics of Szekeres dust models  

CERN Document Server

We obtain an elegant and useful description of the dynamics of Szekeres dust models (in their full generality) by means of "quasi--local" scalar variables constructed by suitable integral distributions that can be interpreted as weighed proper volume averages of the local covariant scalars. In terms of these variables, the field equations and basic physical and geometric quantities are formally identical to their corresponding expressions in the spherically symmetric LTB dust models. Since we can map every Szekeres model to a unique LTB model, rigorous results valid for the latter models can be readily generalized to a non--spherical Szekeres geometry. The new variables lead naturally to an initial value formulation in which all scalars are expressed as scaling laws in terms of their values at an arbitrary initial space slice. These variables also yield a significant simplification of numerical work, ...

2011-01-01

285

[Clinico-hormonal correlations in patients with chronic alcoholic intoxication].  

Science.gov (United States)

Radioimmunochemical assay was used to study the hypophyseal and peripheral hormones activity in 60 patients with chronic alcoholism, stage II. A correlation has been established between the patient's age and prolactin and FSH concentrations, as well as between the duration of the recent hard drinking and the concentrations of prolactin, testosterone, FSH and interstitial cell stimulating hormone. It has been shown that the manifestation of the alcoholic abstinent syndrome depended on the prolactin concentration. The test sensitivity estimated by the prolactin level rise and the testosterone level reduction reached 92.3%. The specificity of the changes detected comprised 25%. A conclusion has been made that the disorders noted in the patients with chronic alcoholic intoxication can be used as an objective test in the alcoholism diagnosis. PMID:3936321

1985-01-01

286

Why the sunspot cycle is double peaked  

CERN Document Server

Many sunspot cycles are double peaked. In 1967 Gnevyshev suggested that actually all cycles have two peaks generated by different physical mechanisms, but sometimes the gap between them is too short for the maxima to be distinguished in indices of the total sunspot activity. Here we show that indeed all cycles have two peaks easily identified in sunspot activity in different latitudinal bands. We study the double peaks in the last 12 sunspot cycles and show that they are manifestation of the two surges of toroidal field - the one generated from the poloidal field advected all the way on the surface to the poles, down to the tachocline and equatorward to sunspot latitudes, and another one generated from the poloidal field diffused at midlatitudes from the surface to the tachocline and transformed there into toroidal field. The existence of these two surges of toroidal field is due to the relative magnitudes of the speed of the large-scale solar meridional ...

2011-01-01

287

The tactical use of constraints and structure in diagnostic problem solving  

British Library Electronic Table of Contents (United Kingdom)

This paper presents a prescriptive account of diagnostic problem solving, or diagnosis, in quality and process control. This paper identifies a general strategy, named branch-and-prune, whose manifestations can be found in disciplines such as medical diagnosis, troubleshooting of devices, and model-based diagnosis in artificial intelligence. The work aims to offer a clear conceptualization of this strategy, based on the notions of structures for the search space, and constraints to the cause's nature.The idea is to treat the search space of candidate explanations as a tree structure, in which general and high-level causal directions are branched into more specific and detailed explanations. Constraints eliminate all but a few branches (pruning), which are explored in more detail. We enumer...

2011-01-01

288

The evolution of human culture during the later Pleistocene: Using fauna to test models on the emergence and nature of "modern" human behavior  

British Library Electronic Table of Contents (United Kingdom)

It has often been argued that the success and spread of modern humans 50,000years ago was due to a series of key behavioral shifts that conferred particular adaptive advantages. And yet, particularly during the African Middle Stone Age (MSA), some of these "modern" behaviors see only patchy expression across time and space. Recent models have proposed a link between the emergence of modern behaviors and environmental degradation and/or demographic stress. Under these models, modern behaviors represent a form of social/economic intensification in response to stress; if this were the case, signs of subsistence intensification should be more common during periods in which these behaviors are manifested than when they are not. In order to test these models, I analyzed faunal remains from Sibud...

2011-01-01

289

The effect of the venom of the yellow Iranian scorpion Odontobuthus doriae on skeletal muscle preparations in vitro  

British Library Electronic Table of Contents (United Kingdom)

The yellow Iranian scorpion Odontobuthus doriae can cause fatal envenoming, but its mechanism of action is unclear. One of the reported manifestations of envenoming is moderate to severe involuntary tremor of skeletal muscle. In order to understand better the mechanism of action of this venom on skeletal muscle function, we examined the effects of the venom in vitro on chick biventer cervicis (CBC) and mouse hemidiaphragm (MHD) nerve muscle preparations. O. doriae venom (0.3-10mg/ml) initially increased and then decreased twitch height. The venom also caused contracture in both preparations. In mouse triangularis sterni preparations, used for all intracellular recording techniques, the venom enhanced the release of acetylcholine and induced repetitive firing of nerve action potentials and ...

2007-01-01

290

The capric-lauric acid and pentadecane combination as phase change material for cooling applications  

Energy Technology Data Exchange (ETDEWEB)

The mixture of 65 mol% capric acid and 35 mol% lauric acid (C-L acid) is a potential latent heat storage material. However, its melting temperature of 18.0 {sup o}C is quite high for low-temperature thermal energy storage. Addition of pentadecane, with a melting point of 9.9 {sup o}C, is proposed. The thermal characteristics of the combination of the C-L acid with pentadecane (CL:P) in different volume ratio are investigated employing the DSC analysis. The actual thermal performance of each CL:P combination is further determined from their radial and axial temperature distribution employing a fabricated thermal storage capsule. The 90:10 CL:P combination manifests an improvement in the melting characteristic of the C-L acid.(author)

2002-03-01

291

Synthesis of ultraviolet curable encapsulating adhesives and their package applications for organic optoelectronic devices  

British Library Electronic Table of Contents (United Kingdom)

With conventional heating process, ultraviolet (UV) illumination, and microwave irradiation, we have successfully synthesized UV curable encapsulating adhesives with excellent gas barrier capabilities, good adhesive strength, moderate hardness, and high refractive indices. The experimental results manifest that the physical properties of lab-made encapsulating adhesives are highly dependent on their chemical structures and synthetic procedure. We also discover that the encapsulating adhesive prepared by microwave irradiation (i.e. encapsulating adhesive VI-MW) exhibits better adhesive strength and higher gas resistance than those prepared by conventional heating process and UV illumination. Furthermore, encapsulating adhesive VI-MW has also been applied for the package of organic light emi...

2011-01-01

292

Search for W-prime boson decaying to electron-neutrino pairs in p anti-p collisions at s**(1/2) = 1.96-TeV  

Energy Technology Data Exchange (ETDEWEB)

The authors present the results of a search for W{prime} boson decaying to electron-neutrino pairs in p{bar p} collisions at a center-of-mass energy of 1.96 TeV, using a data sample corresponding to 205 pb{sup -1} of integrated luminosity collected by the CDF II detector at Fermilab. They observe no evidence for this decay mode and set limits on the production cross section times branching fraction, assuming the neutrinos from W{prime} boson decays to be light. If they assume the manifest left-right symmetric model, they exclude a W{prime} boson with mass less than 788 GeV/c{sup 2} at the 95% confidence level.

2006-11-01

293

Regulation of natural gas: policy and politics, 1938-1978  

Energy Technology Data Exchange (ETDEWEB)

The history of the political process surrounding regulations is traced from the 1930s, when the natural gas industry and the Federal Power Commission were in their infancy. The author traces the changing mandate that Congress has provided the regulators and the instincts for self-preservation that these bureaucrats have manifested when they suspected a change in presidential administration or a new decision from the Supreme Court. Natural gas has been one political issue that has split Congress by region. The economic interests of producer and consumer states have often been at such odds that regulation has involved the question of redistribution of wealth among regions as well as between households and industry. The picture is complicated by the link between gas production and distribution and the production and distribution of coal and oil. 12 figures, 25 tables.

1981-01-01

294

Radiative corrections to the atomic levels in a periodic electromagnetic field  

Energy Technology Data Exchange (ETDEWEB)

The influence of a periodic electromagnetic field on the radiative corrections to the atomic energy levels is studied for the case of ''strong fields'' for which the interaction between the atom and field is of the order or greater than the radiative effects. The analysis is carried out on the basis of the Schwinger-Dirac equation for the propagation function of a bound electron in the field and on the basis of the density matrix in the Furry representation. It is shown that in the strong field approximation the radiative shifts and widths are manifest as radiative corrections to the quasi-energies. In super-high resolution experiments intensity effects in the radiative corrections to the atomic levels are obtained in the case of single-photon resonance. Some multiphoton processes are condidered by taking into account the effect of the field on the radiative structure of the levels.

1982-12-01

295

Quantization in the presence of Gribov ambiguities  

Energy Technology Data Exchange (ETDEWEB)

The non-perturbative validity of covariant BRST-quantization of gauge theories on compact Euclidean space-time manifolds is reviewed. BRST-quantization is related to the construction of a Topological Quantum Field Theory (TQFT) of Witten type on the gauge group. The criterion for the non-perturbative validity of the quantization is that the partition function of the corresponding TQFT does not vanish and that its (equi-variant) BRST-algebra is free of anomalies. I sketch the construction of a TQFT whose partition function is proportional to the generalized Euler-characteristic of the coset space S U (n){sub gauge} / SU(n){sub global} with an associated equi-variant BRST-algebra that manifestly preserves translational symmetry. Some non-perturbative consequences of this approach are discussed. (author)

1999-07-01

296

Phase transition in a simple plasma model  

CERN Document Server

A phase transition of gas-liquid type with an upper critical point is examined which arises in a model of charges of one sign on compensating background (OCP). The phase transition parameters are dependent on the detailed assumptions about the compressibility of the background, but the occurrence of this transition is independent on the background equation of state. In the electron-gas model ('jellium'), this transition appears to rule out Wigner crystallization. A variational principle in statistical mechanics is used to derive so-called Double-OCP model for a superposition of two one-component plasma models for charges of opposite sign. The free energy of this model sets an upper bound to that of a real plasma. Situations are discussed where this transition should manifest itself in anomalies in the approximate description of a non-ideal plasma.

2009-01-01

297

Oral administration of circulating precursors for membrane phosphatides can promote the synthesis of new brain synapses  

British Library Electronic Table of Contents (United Kingdom)

Although cognitive performance in humans and experimental animals can be improved by administering omega-3 fatty acid docosahexaenoic acid (DHA), the neurochemical mechanisms underlying this effect remain uncertain. In general, nutrients or drugs that modify brain function or behavior do so by affecting synaptic transmission, usually by changing the quantities of particular neurotransmitters present within synaptic clefts or by acting directly on neurotransmitter receptors or signal-transduction molecules. We find that DHA also affects synaptic transmission in mammalian brain. Brain cells of gerbils or rats receiving this fatty acid manifest increased levels of phosphatides and of specific presynaptic or postsynaptic proteins. They also exhibit increased numbers of dendritic spines on post...

2008-01-01

298

Modeling of ablation by photospallation using the computer program PUFF/DFRACT  

Energy Technology Data Exchange (ETDEWEB)

In general, macroscopic material failure is a manifestation of irreversible changes at the microscopic level. Many tissues, which may appear to be macroscopically homogeneous, are, at a fundamental microscopic level, a composite material. For example, cornea is composed of a hyaluronic acid matrix in which layers of collagen fibers are overlaid in a crossing pattern. The points where the collagen fibers intersect are potential nucleation sites for microscopic defects, which under the action of tensile stress, nucleate, grow and coalesce to form macroscopic failure planes, or spall planes. Using a model based on microstructural evolution, this paper examines the failure process during photoablation. Specifically, the paper describes a physically motivated, micromechanical model based on the nucleation and growth of spherical voids. This model is then used to simulate photoablation of cornea. Potential for using this model to predict the stress wave and material ...

1995-03-01

299

Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung  

British Library Electronic Table of Contents (United Kingdom)

Fibroblast growth factor (FGF) signaling has been shown to regulate lung epithelial development but its influence on mesenchymal differentiation has been poorly investigated. To study the role of mesenchymal FGF signaling in the differentiation of the mesenchyme and its impact on epithelial morphogenesis, we took advantage of Fgfr2c+/? mice, which due to a splicing switch express Fgfr2b in mesenchymal tissues and manifest Apert syndrome-like phenotypes. Using a set of in vivo and in vitro studies, we show that an autocrine FGF10?FGFR2b signaling loop is established in the mutant lung mesenchyme, which has several consequences. It prevents the entry of the smooth muscle progenitors into the smooth muscle cell (SMC) lineage and results in reduced fibronectin and elastin deposition. Levels of...

2006-01-01

300

Kinetic manifestation of cooperative interaction between quinuclidinyl benzilate and rat brain muscarine cholinoreceptors  

Energy Technology Data Exchange (ETDEWEB)

A study was made of the kinetics of L-(/sup 3/H)quinuclidinyl benzilate binding with membrane-bound muscarine cholinoreceptors from the rat brain. Determination was made of the rate constants of this process, and constants as a function of ligand concentration was investigated, indicating that there is a complex mechanism of interaction of antagonists with muscarine receptor. With up to 3.5 nM concentrations of L-(/sup 3/H)quinuclidinyl benzilate, the binding reaction occurs in two stages: rapid equilibrated binding is followed by a slow process of conformational isomerization of the receptor-ligand complex. At higher ligand concentrations, there is additional drastic increase in constant of rate of ligand binding a new plateau is reached. Such dependence of rate constant on ligand concentration is indicative of the cooperative nature of interaction between antagonists and muscarine receptors. This is possible if there are in the receptor complex several binding sites that play ...

1985-01-01

301

Isomeric states and spin polarization in A approx. 90 nuclei  

Energy Technology Data Exchange (ETDEWEB)

The observed inhibition of M4 transitions in A approx. 90 nuclei has represented a long standing theoretical problem. In particular by calculating first- and second-order configuration mixing contributions to the inhibited M4 lifetimes of /sup 89/Y and /sup 87/Sr, it is found that the first-order perturbative treatment of the residual interaction usually used in shell-model calculations is unjustified in this case. Using random-phase approximation techniques, the renormalization effects of collective (''giant'') M4 resonances in /sup 88/Sr on the low energy M4 transitions in /sup 89/Y and /sup 87/Sr are investigated. It is concluded that the observed retardation of M4 lifetimes in these nuclei is consistent with the manifestation of nuclear spin polarization.

1980-04-01

302

Health risks arising from ionizing radiation and chemical pollutants  

International Nuclear Information System (INIS)

In quantifying health risks arising from radiation exposure and synergistic effects promoted by radiation the dose-effect relationship must be used as a basis. Special problems arise in the extrapolation of experimental results or in the treatment of data in the region of low doses administered over long periods of time. For radiation protection purposes, especially manifestations of cancer and genetic effects are significant. The International Commission on Radiation Protection has published binding guiding values on the basis of which to assess the risk of cancer. The cancer risk and genetic risks are estimated for relevant dose ranges and compared with other factors of civilization. For the most important chemical pollutants emitted into the environment the possibilities of impacts arising from synergistic effects are discussed on the basis of the rules and regulations specified in German antipollution legislation. (orig.) 891 HP/orig. 892 MKO.

1979-10-03

303

Growth factor signalling in the regulation of -cell fate  

British Library Electronic Table of Contents (United Kingdom)

Glucagon plays critical roles in regulating glucose homeostasis, mainly by counteracting the effects of insulin. Consequently, the dysregulated glucagon secretion that is evident in type 2 diabetes has significant implications in the pathophysiology of the disease. Glucagon secretion from pancreatic -cells has been suggested to be modulated by blood glucose, signals from the nervous system and endocrine components. In addition to these regulators, intraislet factors acting in a paracrine manner from neighbouring -cells are emerging as central modulator(s) of -cell biology. One of the most important of these paracrine factors, insulin, modulates glucagon secretion. Indeed, the -cell-specific insulin receptor knockout (IRKO) mouse manifests hypersecretion of glucagon in the postprandial stag...

2011-01-01

304

Feynman rules in N=2 projective superspace. II. Massive hypermultiplets  

International Nuclear Information System (INIS)

For pt.I see ibid., vol.516, p.426-48, 1998. Manifest N=2 supersymmetric hypermultiplet mass terms can be introduced in the projective N=2 superspace formalism. In the case of complex hypermultiplets, where the gauge covariantized spinor derivatives have an explicit representation in terms of gauge prepotentials, it is possible to interpret such masses as vacuum expectation values of an Abelian vector multiplet. The duality transformation that relates the N=2 off-shell projective description of the hypermultiplet to the on-shell description involving two N=1 chiral superfields allows us to obtain the massive propagators of the N=1 complex linear fields in the projective hypermultiplet. The N=1 massive propagators of the component superfields in the projective hypermultiplet suggest a possible ansatz for the N=2 massive propagator, which agrees with an explicit calculation in N=2 superspace. (orig.).

305

Exposure accidents outside basic nuclear installations; Les accidents d`exposition en dehors des installations nucleaires de base  

Energy Technology Data Exchange (ETDEWEB)

With the exception of the 1945 Hiroshima and Nagasaki nuclear weapon explosions and the 1986 Tchernobyl reactor accident, most of the radiation accidents concerns the medical and the traditional industrial sectors. The seriousness of the accident is directly function of the absorbed dose. The paper, first, gives the definition of a radiologic accident with its specific criteria and pathological manifestations. Then, some famous historical accidents are reviewed from the discovery of X-rays to recent acute irradiations due to the careless manipulation of radiation sources. From this analysis, three main causes are put forward: the dysfunction of nuclear medicine apparatuses, the victims` lack of training and knowledge of the risks, and the non-identification or the loss of radiation sources. (J.S.). 1 photo.

1996-04-01

306

Estrogen and raloxifene improve metaphyseal fracture healing in the early phase of osteoporosis. A new fracture-healing model at the tibia in rat  

British Library Electronic Table of Contents (United Kingdom)

Background Fracture healing in osteoporosis is delayed. Quality and speed of fracture healing in osteoporotic fractures are crucial with regard to the outcome of patients. The question arises whether established antiosteoporotic drugs can further improve fracture healing. Materials and methods Osteoporosis manifests predominantly in the metaphyseal bone. Nevertheless, an established metaphyseal fracture model is lacking. A standardized metaphyseal fracture-healing model with stable plate fixation was developed for rat tibiae. The healing process was analyzed by biomechanical, gene expression, and histomorphometric methods in ovariectomized (OVX) and sham-operated rats (SHAM), compared to standardized estrogen (E)- and raloxifene (R)-supplemented diets. Results Estrogen and raloxifene impro...

2010-01-01

307

Effects of velocity-dependent force on the magnetic form factors of odd-Z  

International Nuclear Information System (INIS)

We investigate the effects of the velocity-dependent force on the magnetic form factors and magnetic moments of odd-Z nuclei. The form factors are calculated with the harmonic-oscillator wavefunctions. It is found that the contributions of the velocity-dependent force manifest themselves in the very large momentum transfer region (q?4 fm-1). In the low and medium q region the contributions of the velocity-dependent force are very small compared with those without this force. However, in the high-q region the contributions of the velocity-dependent force are larger than the normal form factors. The diffraction structures beyond the existing experimental data are found after the contributions of the velocity-dependent force are included. The formula of the correction to the single particle magnetic moment due to the velocity-dependent force is reproduced exactly in the long-wavelength limit (q=0) of the M1 form factor. (authors)

2008-03-01

308

Effective numbers of multiquark fluctons in atomic nuclei  

International Nuclear Information System (INIS)

A technique is developed for calculation of the total weight of the quark clusters-fluctons in atomic nuclei. The microscopical proof of Blochintsev formula is carried out and its refinement is obtained (spin-charge and quark factors enter the formula). It is shown that high values of the correlation radius (R_c #approx =# 0.75 fm or 1.0 fm in various papers) obtained from the experimental data making use of the above formula correspond to internucleon distances in flucton of 0.3-0.4 fm, which is by a factor of #approx# 2.5 lower. This means that the flucton hardness is due to free manifestation of hidden color at those distances (the appropriate probabilities are presented).

309

Effect of electrostimulated deformation on thin structure and mechanical properties of polycrystalline molybdenum  

Energy Technology Data Exchange (ETDEWEB)

To clarify the effect of electrostimulated deformation on the fine structure and mechanical properties of polycrystalline molybdenum the experiments on the flattening of wire 0.8 mm in diameter into a strip 0.4 mm thick and its further rolling to 0.1 mm thickness using the electric current of high density in the deformation zone and without it, are carried out. As a result of the electric current use the strip density has increased by more than 20%, the same plasticity being preserved. The changes above are explained by the transformations in the fine structure of the deformed metal, which are manifested in more uniform distribution of dislocations and impurities in the grain boundaries in wide angles of the disoriented subgrains.

1981-01-01

310

Destructive spondyloarthropathy in hemodialysis patients. Report of four cases and prospective study  

Energy Technology Data Exchange (ETDEWEB)

A destructive spondyloarthropathy is reported in four patients undergoing maintenance hemodialysis for chronic renal disease. In a separate investigation a controlled, prospective radiographic study of the cervical spine revealed this spondyloarthropathy in 4 (15%) of 26 long-term dialysis patients. A single disk level was involved in three patients, and two disc levels were involved in one patient. This spondyloarthropathy correlated with the duration of dialysis but not with the radiographic evidence of renal osteodystrophy or severity of laboratory abnormalities associated with hyperparathyroidism. Three of these four patients also had discovertebral erosions or destruction involving the lumbar spine. Cervical spine flexion views revealed evidence of ligamentous laxity or instability in three (12%) dialysis patients, all with vertebral resorption and disc space narrowing. It is postulated that this instability may contribute to the development of cervical discovertebral lesions or ...

1988-04-01

311

Dependence of the evolution of the cavity radiation of a coherently pumped correlated emission laser on dephasing and phase fluctuation  

CERN Document Server

Analysis of the dynamics of the cavity radiation of a coherently pumped correlated emission laser is presented. The phase fluctuation and dephasing are found to affect the time evolution of the two-mode squeezing and intensity of the cavity radiation significantly. The intensity and degree of the two-mode squeezing increase at early stages of the process with time, but this trend changes rapidly afterwards. It is also shown that they increase with phase fluctuation and dephasing in the strong driving limit, however the situation appears to be opposite in the weak driving limit. This essentially suggests that the phase fluctuation and dephasing weaken the coherence induced by a strong driving mechanism so that the spontaneous emission gets a chance. The other important aspect of the phase fluctuation, in this regard, is the relaxation of the time at which the maximum squeezing is manifested as well as the time in which the radiation remains in a squeezed state.

2010-01-01

312

Cumulative effect of X-ray radiation and inflammatory reaction on the circadian rhythm of tyrosine aminotransferase in the liver of mice  

International Nuclear Information System (INIS)

The activity of tyrosine aminotransferase (TAT) in the liver of mice subjected simultaneously to ionizing radiation and to local inflammatory process showed in the first 24 hours of the experiment statistically significant changes resulting from summation of the harmful effects of both factors. In the second 24-hour period an evident tendency was observed for return of a normal circadian rhythm of the enzyme. This points to presence of an endogenous mechanism of suppression of the manifestations of significant desynchronization of the circadian rhythm. The paper contains also a trial of mathematical analysis of changes in TAT activity in the circadian rhythm, a description and analysis or the suppression process, qualitative and quantitative determination of the phenomenon of cumulation of the effects of powerful stress factors acting on the animal organism. The obtained results were compared with the results of investigations of TAT activity changes obtained in ...

1980-01-01

313

Combining satellite data and models to estimate cloud radiative effect at the surface and in the atmosphere  

British Library Electronic Table of Contents (United Kingdom)

Abstract Satellite measurements and numerical forecast model reanalysis data are used to compute an updated estimate of the cloud radiative effect on the global multi-annual mean radiative energy budget of the atmosphere and surface. The cloud radiative cooling effect through reflection of short wave radiation dominates over the long wave heating effect, resulting in a net cooling of the climate system of - 21 Wm-2. The short wave radiative effect of cloud is primarily manifest as a reduction in the solar radiation absorbed at the surface of - 53 Wm-2. Clouds impact long wave radiation by heating the moist tropical atmosphere (up to around 40 Wm-2 for global annual means) while enhancing the radiative cooling of the atmosphere over other regions, in particular higher latitudes and sub-trop...

2011-01-01

314

Chemical isomeric effects on propanol glassy structures  

Energy Technology Data Exchange (ETDEWEB)

We have studied the structure of both propanol isomers in their glassy and crystalline states by neutron diffraction. The glass-transition temperatures of 1- and 2-propanol are about 98 and 115 K, respectively and, surprisingly, even larger differences are observed for the melting temperatures of the stable crystals, which are 148 and 185 K, respectively. Their supercooled liquid phases show rather different relaxation spectra, 1-propanol manifesting strong deviations from Debye behavior, whereas 2-propanol shows a far weaker effect. We discuss the spectra obtained for the static structure factor and the static pair correlation function D(r). There is a noticeable difference in the position of the first sharp diffraction peak, which clearly indicates a density change, well correlated with the period of the intermolecular oscillations shown by D(r). (orig.)

2002-07-01

315

Chemical isomeric effects on propanol glassy structures  

International Nuclear Information System (INIS)

We have studied the structure of both propanol isomers in their glassy and crystalline states by neutron diffraction. The glass-transition temperatures of 1- and 2-propanol are about 98 and 115 K, respectively and, surprisingly, even larger differences are observed for the melting temperatures of the stable crystals, which are 148 and 185 K, respectively. Their supercooled liquid phases show rather different relaxation spectra, 1-propanol manifesting strong deviations from Debye behavior, whereas 2-propanol shows a far weaker effect. We discuss the spectra obtained for the static structure factor and the static pair correlation function D(r). There is a noticeable difference in the position of the first sharp diffraction peak, which clearly indicates a density change, well correlated with the period of the intermolecular oscillations shown by D(r). (orig.)

316

Carbon dioxide adsorption on carbon nanomaterials  

British Library Electronic Table of Contents (United Kingdom)

The adsorption of CO2 on a number of activated carbons, thermal carbon black, and oxide materials at 195 K was studied using static and dynamic techniques. The landing surface areas ?(CO2) ? 0.19 nm2 on thermal carbon black and the absolute values of sorption for P/P 0 < 0.4 were determined. The density of adsorbed CO2 in the micropore volume was estimated at ?(CO2) = 0.91 g/cm3. It was demonstrated that the previously found effect of a weakening of the sorption interaction of nitrogen molecules with thin-walled materials (which manifested itself in an analysis of sorption isotherms by a comparative method) was pronounced to a lesser degree for the sorption of CO2. At the same time, the presence of supermicropores in activated carbon samples resulted in overestimated values of surface area...

2010-01-01

317

Breathers in Josephson junction ladders: Resonances and electromagnetic wave spectroscopy  

DEFF Research Database (Denmark)

We present a theoretical study of the resonant interaction between dynamical localized states (discrete breathers) and linear electromagnetic excitations (EE's) in Josephson junction ladders. By making use of direct numerical simulations we find that such an interaction manifests itself by resonant steps and various sharp switchings (voltage jumps) in the current-voltage characteristics. Moreover, the power of ac oscillations away from the breather center (the breather tail) displays singularities as the externally applied dc bias decreases. All these features may be mapped to the spectrum of EE's that has been derived analytically and numerically. Using an improved analysis of the breather tail, a spectroscopy of the EE's is developed, The nature of breather instability driven by localized EE's is established.

2001-01-01

318

Antiferromagnetic ordering of defects in GaAs  

Energy Technology Data Exchange (ETDEWEB)

The magnetic susceptibility of GaAs samples containing a large concentration of native defects was investigated by dc magnetization measurements. Thin GaAs films grown by molecular-beam epitaxy at very low temperatures and bulk GaAs:S samples irradiated with fast neutrons have been studied. For all samples, the susceptibility follows a Curie-Weiss law, indicating the presence of localized magnetic moments. These moments are attributed to unpaired spins located at the native defects. Negative Curie-Weiss temperatures found for both neutron-irradiated and low-temperature-grown GaAs is a clear manifestation of an antiferromagnetic interaction between the moments. The presence of a highly inhomogeneous distribution of native defects has to be assumed to account for the observed antiferromagnetic ordering.

1992-10-15

319

An Intrinsic Approach to Forces in Magnetoelectric Media  

CERN Document Server

This paper offers a conceptually straightforward method for the calculation of stresses in polarisable media based on the notion of a drive form and its property of being closed in spacetimes with symmetry. After an outline of the notation required to exploit the powerful exterior calculus of differential forms, a discussion of the relation between Killing isometries and conservation laws for smooth and distributional drive forms is given. Instantaneous forces on isolated spacetime domains and regions with interfaces are defined, based on manifestly covariant equations of motion. The remaining sections apply these notions to media that sustain electromagnetic stresses, with emphasis on homogeneous magnetoelectric material. An explicit calculation of the average pressure exerted by a monochromatic wave normally incident on a homogeneous, magnetoelectric slab in vacuo is presented and the concluding section summarizes how this pressure depends on the parameters in ...

2008-01-01

320

Amyloid oligomers: spectroscopic characterization of amyloidogenic protein states  

British Library Electronic Table of Contents (United Kingdom)

It is assumed that protein fibrils manifested in amyloidosis result from an aggregation reaction involving small misfolded protein sequences being in an `oligomeric' or `prefibrillar' state. This review covers recent optical spectroscopic studies of amyloid protein misfolding, oligomerization and amyloid fibril growth. Although amyloid fibrils have been studied using established protein-characterization techniques throughout the years, their oligomeric precursor states require sensitive detection in real-time. Here, fluorescent staining is commonly performed using thioflavin T and other small fluorescent molecules such as 4-(dicyanovinyl)- julolidine and 1-amino-8-naphtalene sulphonate that have high affinity to hydrophobic patches. Thus, populated oligomeric intermediates and related `pre...

2010-01-01

321

A new model of coal-water interaction and relevance for dewatering  

Energy Technology Data Exchange (ETDEWEB)

This project is concerned with a basic scientific question concerning the properties of coal--to what extent is the ability of coal to hold moisture a manifestation of the well-known ability of coal to swell, when exposed to good solvents The question implies that the long-held belief that coal holds a significant portion of its moisture by classical capillary condensation processes, is possibly in error. It is likely that a sound approach to permanent drying would involve highly crosslinking the coal at mild drying conditions. The crosslinked coal could not swell sufficiently to hold much water. It is identifying processes to achieve this goal, that constitute the objective of the second phase of this work. 25 refs., 4 figs., 1 tab.

1991-01-01

322

Variable Frequency Microwave Synthesis of Silver Nanoparticles  

Energy Technology Data Exchange (ETDEWEB)

Synthesis of silver nanoparticles based on a polyol process and variable frequency microwave (VFM) was investigated. Comparing to a thermal method, the reaction by VFM radiation was much faster. The effects of silver nitrate concentration, poly(N-vinylpyrrolidone) (PVP) concentration, reaction time and reaction temperature were studied. It was found that the higher concentration of silver nitrate, longer reaction time and higher temperature increased the particle size while the higher concentration of PVP decreased the particle size.

2006-02-15

323

One-dimensional numerical simulation of free-electron laser (FEL) amplifier with incorporate variable-parameter wiggler magnets  

International Nuclear Information System (INIS)

A physical model of free-electron laser (FEL) amplifier with variable-parameter wiggler magnets for one-dimensional numerical simulation is presented and a numerical example is given. The wiggler parameters, efficiency of energy conversion between electron beam and laser field, laser intensity, phase-space distributions and energy spectrum of electrons are computed. The period of synchronous oscillation and saturation value of laser intensity agree with estimated one.

324

Flow control with variable inflow as an alternative to conventional nozzle group control - automatic control of large capacity steam turbines  

International Nuclear Information System (INIS)

In the case of large capacity steam turbines the conventional nozzle group control is, for mechanical and thermodynamic reasons, diminishing more and more in importance in favour of variable pressure control. A design for constant-pressure operation as an alternative to nozzle group control is described; this demonstrates a series of important advantages compared with the latter. (orig.).

325

Conference on climate and water. Volume 2  

Energy Technology Data Exchange (ETDEWEB)

This book contains the Proceedings of the Conference on Climate and Water under the following groupings: Impacts of climatic variability and change-resulting from the changes in hydrological variables; Aquatic environment; Terrestrial environment; Coastal zones and navigation; Urban and industrial water supply and drainage; Energy production; Intropogenic changes of climate and water management problems; Flood potential; Irrigation and land drainage.

1989-12-31

326

Conference on climate and water  

Energy Technology Data Exchange (ETDEWEB)

This book contains the Proceedings of the Conference on Climate and Water under the following groupings: Impacts of climatic variability and change-resulting from the changes in hydrological variables; Aquatic environment; Terrestrial environment; Coastal zones and navigation; Urban and industrial water supply and drainage; Energy production; Intropogenic changes of climate and water management problems; Flood potential; Irrigation and land drainage.

1989-01-01

327

Variable-speed generation enhances hydro operation  

Energy Technology Data Exchange (ETDEWEB)

Two major developments have given impetus to wider adoption of variable-speed turbine/generators in hydroelectric plants, both essentially environmental: (1) the need for stream-bed stability below river dams, and (2) the need to minimize fish damage. Also, the need to stabilize pumped-storage and generating efficiencies to match extreme changes in head levels has been a driving force. Variable-speed operation in hydro applications is relatively new to North America. In other parts of the world, it has been used in pumped-storage plants since 1971. In the US, and increasing potential exists for variable-speed hydro, considering the 30 pumped-storage plants already in operation and several river plants struggling with high head fluctuations--including four at stations operated by the Bonneville Power Administration. Several modifications to hydro-plant hardware and operating procedures are actively being considered at ...

1993-07-01

328

Intrapartum FHR monitoring and neonatal CT brain scan  

Energy Technology Data Exchange (ETDEWEB)

The effect of fetal distress on the neonatal brain was investigated by neonatal CT brain scan, FHR monitoring and mode of delivery. This study involved 11 cases of full term vertex delivery in which FHR was recorded by fetal direct ECG during the second stage labor. All infants weighed 2,500 g or more. FHR monitoring was evaluated by Hon's classification. Neonatal brain edema was evaluated by cranial CT histgraphic analysis (Nakada's method). 1) Subdural hemorrhage was noted in 6 of 7 infants delivered by vacuum extraction or fundal pressure (Kristeller's method). 2) Intracranial hemorrhage was demonstrated in all of 3 infants with 5-min. Apgar score 7 or less. 3) Two cases with prolonged bradycardia and no variability had intraventricular or intracerebral hemorrhage which resulted in severe central nervous system damage. 4) The degree of neonatal brain edema correlated with 5-min. Apgar score. 5) One case with prolonged bradycardia and ...

1982-12-01

329

Intrapartum FHR monitoring and neonatal CT brain scan  

International Nuclear Information System (INIS)

The effect of fetal distress on the neonatal brain was investigated by neonatal CT brain scan, FHR monitoring and mode of delivery. This study involved 11 cases of full term vertex delivery in which FHR was recorded by fetal direct ECG during the second stage labor. All infants weighed 2,500 g or more. FHR monitoring was evaluated by Hon's classification. Neonatal brain edema was evaluated by cranial CT histgraphic analysis (Nakada's method). 1) Subdural hemorrhage was noted in 6 of 7 infants delivered by vacuum extraction or fundal pressure (Kristeller's method). 2) Intracranial hemorrhage was demonstrated in all of 3 infants with 5-min. Apgar score 7 or less. 3) Two cases with prolonged bradycardia and no variability had intraventricular or intracerebral hemorrhage which resulted in severe central nervous system damage. 4) The degree of neonatal brain edema correlated with 5-min. Apgar score. 5) One case with prolonged bradycardia and no ...

1982-01-01

330

Clinical features and {sup 123}I-FP-CIT SPECT imaging in drug-induced parkinsonism and Parkinson's disease  

Energy Technology Data Exchange (ETDEWEB)

To determine clinical predictors and accuracy of {sup 123}I-FP-CIT SPECT imaging in the differentiation of drug-induced parkinsonism (DIP) and Parkinson's disease (PD). Several clinical features and {sup 123}I-FP-CIT SPECT images in 32 patients with DIP, 25 patients with PD unmasked by antidopaminergic drugs (PDu) and 22 patients with PD without a previous history of antidopaminergic treatment (PDc) were retrospectively evaluated. DIP and PD shared all clinical features except symmetry of parkinsonian signs which was more frequently observed in patients with DIP (46.9%) than in patients with PDu (16.0%, p<0.05) or PDc (4.5%, p<0.01). Qualitatively {sup 123}I-FP-CIT SPECT images were normal in 29 patients with DIP (90.6%) and abnormal in all patients with PD, and this imaging technique showed high levels of accuracy. DIP and PD are difficult to differentiate based on clinical ...

2010-03-15

331

Various clinical situations and their influence on linear occlusion in treating combination syndrome: a discussion of treatment options.  

Science.gov (United States)

Eliminating anterior tooth contact is paramount when treating combination syndrome. It is possible to do so through the use of linear occlusion with a non-interceptive arrangement and the bilateral fulcrum of protrusive stability. The presence of mandibular anterior teeth often complicates this procedure. When establishing the horizontal plane of occlusion, clinical circumstances often necessitate modifications; nevertheless, certain principles must be incorporated into the design of the prostheses. Clinical circumstances may dictate altering the approach but these principles must be maintained to eliminate anterior hyperfunction. PMID:15055634

332

Value of computed Tomography in re-staging patients undergoing second-look laparotomy for ovarian cancer  

International Nuclear Information System (INIS)

Twenty-five patients with ovarian carcinoma who had been operated and treated with chemotherapy underwent clinical examination and CT before reintervention (second-look laparotomy) to detect the presence of eventual recurrences. The prediction of recurrence based on CT and clinical findings was compared with the surgical findings at reintervention. CT proved to be more accurate than clinical examination in detecting recurrences; this was especially true for masses in the abdominal cavity, with the exception of small peritoneal nodules. The authors suggest the use of CT for staging the patients candidate to reintervention. This might help to avoid reintervantion in patients with persistent disease and to plan treatment.

1991-01-01

333

The role of interferons in the treatment of osteosarcoma  

British Library Electronic Table of Contents (United Kingdom)

Interferons, a group of cytokines with antiangiogenic, direct antitumour and immunostimulating properties, have shown significant activity against osteosarcoma in vitro and in xenograft models. They have also been used in osteosarcoma clinical trials as a single adjuvant to surgery, with an apparent increase in relapse-free survival. In the ongoing EURAMOS 1 clinical trial, interferon a-2b is evaluated as an adjuvant treatment in osteosarcoma. This article reviews the rationale for the use of interferon in cancer with special reference to the treatment of osteosarcoma, including all published data of clinical efficacy in this disease. Pediatr Blood Cancer 2010;54:350-354. Copyright 2009 Wiley-Liss, Inc.

2010-01-01

334

Clinical magnetic resonance imaging with nuclear medicine correlation  

Energy Technology Data Exchange (ETDEWEB)

The current role of magnetic resonance imaging (MRI) in different organ systems is discussed and compared to nuclear medicine and to other available clinical diagnostic modalities. The value of optimizing radiofrequency pulse sequence selection to provide additional tissue characterization is also described. The results of nuclear medicine and MRI studies in 56 patients are compared to evaluate the clinical diagnostic contribution of each imaging modality for various pathological processes. In addition, the state-of-the-art MRI systems and future development in MRI technology with its potential contribution is defined.

1985-08-01

335

[Characteristics of the clinical picture and course of chronic alcoholic intoxication in patients with various types of neuroendocrine changes].  

Science.gov (United States)

Clinical and hormonal indices of androgenic activity were compared in 118 males chronically intoxicated with alcohol. The population was divided into two groups with respect to their clinical and hormonal androgenic indices: 76 patients with (Group 1), and 46 patients without (Group 2) androgenic insufficiency. Distinct signs and syndromes of alcohol addiction were shown to correlate with the extent of cross-regulation impairment within hypothalamo-hypophyseo-gonadal system. This was particularly derived from comparison of clinical picture of chronic alcohol intoxication and hormone activity in the groups. Conventional therapy failed to restore the neuroendocrine indices that was apparently due to inhibition of cross-regulation links in the hypothalamo-hypophyseo-gonadal system at several stages of alcohol addiction. PMID:3223149

1988-01-01

336

Wake-Up Stroke: Clinical and Neuroimaging Characteristics  

UK PubMed Central (United Kingdom)

BackgroundApproximately 25% of ischemic stroke patients awaken with neurological deficits. In these patients, in whom the time from symptom onset is uncertain, brain imaging is a...Full Text Available

2010-03-01

337

Vitamin D and Serum Cytokines in a Randomized Clinical Trial  

UK PubMed Central (United Kingdom)

Background. The role of vitamin D in the body's ability to fight influenza and URI's may be dependent on regulation of specific cytokines that participate in the host inflammatory...Full Text Available

2010-01-01

338

Translational bioinformatics and healthcare informatics: computational and ethical challenges.  

Science.gov (United States)

Exponentially growing biological and bioinformatics data sets present a challenge and an opportunity for researchers to contribute to the understanding of the genetic basis of phenotypes. Due to breakthroughs in microarray technology, it is possible to simultaneously monitor the expressions of thousands of genes, and it is imperative that researchers have access to the clinical data to understand the genetics and proteomics of the diseased tissue. This technology could be a landmark in personalized medicine, which will provide storage for clinical and genetic data in electronic health records (EHRs). In this paper, we explore the computational and ethical challenges that emanate from the intersection of bioinformatics and healthcare informatics research. We describe the current situation of the EHR and its capabilities to store clinical and genetic data and then discuss the Genetic Information Nondiscrimination Act. ...

2009-09-16

339

The management of pain following laminectomy for lumbar disc lesions.  

UK PubMed Central (United Kingdom)

Assessment of the results of laminectomy for lumbar disc lesions is unsatisfactory, but it seems that some degree of recurrent pain is virtually inevitable. The clinical features and incidence of the...Full Text Available

1981-07-01

340

The informationist: building evidence for an emerging health profession*  

UK PubMed Central (United Kingdom)

Background:To encourage evidence-based practice, an Annals of Internal Medicine editorial called for a new professional on clinical teams: an informationist trained...Full Text Available

2010-04-01

341

The importance of radiation quality for optimisation in radiology  

UK PubMed Central (United Kingdom)

Selection of the appropriate radiation quality is an important aspect of optimisation for every clinical imaging task in radiology, since it affects both image quality and patient dose. Spreadsheet...Full Text Available

342

The Johns Hopkins Hospital Network  

UK PubMed Central (United Kingdom)

The Johns Hopkins Hospital has initiated an ambitious program to apply modern technologies to the development of a new, comprehensive clinical information system. One component of this system is a...Full Text Available

1985-11-13

343

The Epidemiology of Cosmetic Treatments for Corneal Opacities in a Korean Population  

UK PubMed Central (United Kingdom)

PurposeTo describe etiologies and clinical characteristics of corneal opacities leading patients to seek cosmetic treatments.MethodsThe medical records...Full Text Available

2010-06-01

344

Synthesis, Characterization and Chondroprotective Properties of a Hyaluronan Thioethyl Ether Derivative  

UK PubMed Central (United Kingdom)

Hyaluronan (HA), a non-sulfated glycosaminoglycan, is widely used in the clinic for viscosurgery, viscosupplementation, and treatment of osteoarthritis. Four decades of chemical modification...Full Text Available

2008-04-01

345

Suicidality: Prospective Assessment of Occurrence in Clinical ...  

Science.gov (United States)

... was associated with at least some 360 intent to ... herself, at least to 366 some degree, can be ... As prospective assessment instruments for suicidality are created ...

346

Social, Clinical and Microbiological Differential Characteristics of Tuberculosis among Immigrants in Spain  

UK PubMed Central (United Kingdom)

BackgroundTo identify the differential tuberculosis (TB) characteristics within the immigrant population with respect to natives in Spain.Methodology/Principal...Full Text Available

347

SECTION 3.0 TRIAL CONDUCT  

Science.gov (United States)

... adverse events and potential major events. 3.2.2.4 Clinical Events Committee (CEC) The independent CEC (cardiologists and neurologists ...

348

RESPIRATION INJURIES AND HYDROLYSIN L-103 ...  

Science.gov (United States)

... their clothes set afire. One patient fell into a hot cupola furnace. Steam burns were observed for four patients. In the clinical ...

1963-01-28

349

Proteomic strategies in multiple sclerosis and its animal models  

UK PubMed Central (United Kingdom)

The early and precise diagnosis, the prognosis, and the clinical management of multiple sclerosis, remain a considerable challenge. In recent years, the development of novel and powerful proteomic...Full Text Available

2007-10-16

350

Principles of antibody therapy.  

UK PubMed Central (United Kingdom)

The success of monoclonal antibodies in clinical practice is dependent on good design. Finding a suitable target is the most important part as other properties of the antibody can be altered by genetic...Full Text Available

1992-12-05

351

Preclinical Models for Neuroblastoma: Establishing a Baseline for Treatment  

UK PubMed Central (United Kingdom)

BackgroundPreclinical models of pediatric cancers are essential for testing new chemotherapeutic combinations for clinical trials. The most widely used ...Full Text Available

352

Orbital lymphoma: Role of radiation  

UK PubMed Central (United Kingdom)

The purpose of this article is to review the literature for clinical presentation, treatment, outcome and complications of using radiotherapy for the treatment of orbital lymphoma. For this, MEDLINE,...Full Text Available

2009-03-01

353

Optical Coherence Tomography Findings in Idiopathic Macular Holes  

UK PubMed Central (United Kingdom)

Purpose. To describe the characteristics of idiopathic macular holes (MH) on optical coherence tomography (OCT) and correlate OCT with clinical assessment. Design....Full Text Available

2011-01-01

354

Nineteen Cases of Plague in Arizona  

UK PubMed Central (United Kingdom)

We review the cases of 19 successfully treated plague patients, with emphasis on the clinical and epidemiologic features of the disease. Proper staining and culturing of bubo aspirates; prompt institution...Full Text Available

1985-05-01

355

Newer molecules in the treatment of schizophrenia: A clinical update  

UK PubMed Central (United Kingdom)

Schizophrenia is a heterogeneous psychiatric disorder in which multiple neurotransmitter systems have been implicated. Increased and decreased dopamine transmission in the subcortical meso-limbic and...Full Text Available

2011-04-01

356

Neuroradiologic and Neurophysiologic Findings of Neuralgic Amyotrophy  

UK PubMed Central (United Kingdom)

ObjectiveNeuralgic amyotrophy (NA) is a distinct clinical syndrome that is characterized by the acute onset of shoulder and arm pain, weakness, and sensory loss. The purpose of this...Full Text Available

2010-11-01

357

Necrotizing sialometaplasia of tongue  

UK PubMed Central (United Kingdom)

Necrotizing sialometaplasia, is a benign inflammatory lesion primarily involving the minor salivary glands of the hard palate. The lesion often presents itself as a deep-seated palatal ulcer with clinical...Full Text Available

2009-01-01

358

Model for assessing psychosocial problems.  

UK PubMed Central (United Kingdom)

The Model for the Assessment of Psychosocial Problems (MAPP) can help family medicine residents effectively assess patients with psychosocial problems. Following a patient-centred clinical method, MAPP...Full Text Available

1996-02-01

359

Intraocular coenurosis: a case report.  

UK PubMed Central (United Kingdom)

A case of intraocular coenurosis was clinically diagnosed and treated with praziquantel. The drug destroyed the coenurus, but vision was lost through toxic endophthalmitis and retinal detachment. There...Full Text Available

1991-07-01

360

Immunological reagents  

UK PubMed Central (United Kingdom)

The need for material standards in the field of clinical immunology, together with the mode of operation of the combined World Health Organization/International Union of Immunological Societies programme...Full Text Available

1976-01-01

361

Imaging immune response in vivo  

UK PubMed Central (United Kingdom)

PurposeClinical trials have commenced to evaluate the feasibility of targeting malignant gliomas with genetically engineered cytolytic T-cells (CTLs) delivered directly...Full Text Available

2008-06-15

362

Highlights from the III International Symposium of Thrombosis and Anticoagulation (ISTA), October 14?16, 2010, S?o Paulo, Brazil  

British Library Electronic Table of Contents (United Kingdom)

To discuss and share knowledge around advances in the care of patients with thrombotic disorders, the Third International Symposium of Thrombosis and Anticoagulation was held in S?o Paulo, Brazil, from October 14?16, 2010. This scientific program was developed by clinicians for clinicians, and was promoted by four major clinical research institutes: the Brazilian Clinical Research Institute, the Duke Clinical Research Institute of the Duke University School of Medicine, the Canadian VIGOUR Centre, and the Uppsala Clinical Research Center. Comprising 3?days of academic presentations and open discussion, the symposium had as its primary goal to educate, motivate, and inspire internists, cardiologists, hematologists, and other physicians by convening national and international visionaries, th...

2011-01-01

363

Foveomacular retinitis.  

UK PubMed Central (United Kingdom)

A group of patients is described who developed the clinical features of foveomacular retinitis. No causative factors were isolated, and all patients strongly denied any type of sun gazing. It is possible...Full Text Available

1986-11-01

364

Experience of isolated sleep paralysis in clinical practice in Nigeria.  

UK PubMed Central (United Kingdom)

The supernatural fears associated with the experience of isolated sleep paralysis in the culture of developing countries is sometimes associated with the evolution of somatic symptoms of psychological...Full Text Available

1992-06-01

365

Epidemiology, prevention and control of legionellosis: memorandum from a WHO meeting.  

UK PubMed Central (United Kingdom)

This Memorandum describes the following aspects of legionellosis: clinical presentations of legionella infection, general epidemiology (including nosocomial outbreaks and travel-associated legionnaires'...Full Text Available

1990-01-01

366

Duodenal ileus caused by a calf feeding nipple in a cow  

UK PubMed Central (United Kingdom)

BackgroundThe aim of this report was to describe duodenal obstruction caused by a rubber foreign body in a cow.Case PresentationThe clinical, biochemical...Full Text Available

367

Cutaneous Scarring: A Clinical Review  

UK PubMed Central (United Kingdom)

Cutaneous scarring can cause patients symptoms ranging from the psychological to physical pain. Although the process of normal scarring is well described the ultimate cause of pathological scarring...Full Text Available

2009-01-01

368

Computed tomography of head in Clinic Pediatrics  

Energy Technology Data Exchange (ETDEWEB)

138 unselected head tomographies of children by computer are reported and analysed. The major aspect stressed by the authors is the excellent precision of this radiological technique.

1982-02-01

369

Cognitive and Functional Decline in Huntington's Disease: Dementia Criteria Revisited  

UK PubMed Central (United Kingdom)

The importance of designating criteria for diagnosing dementia lies in its implications for clinical treatment, research, caregiving, and decision-making. Dementia diagnosis in Huntington's...Full Text Available

2010-07-15

370

Coccygectomy with or without periosteal resection  

UK PubMed Central (United Kingdom)

The purpose of this study was to compare the clinical outcomes and wound complications in coccygectomy with or without subperiosteal resection. This retrospective study included 25 patients who underwent...Full Text Available

2010-04-01

371

Clinical, virological and immunological responses in Danish HIV patients receiving raltegravir as part of a salvage regimen  

DEFF Research Database (Denmark)

Raltegravir is the first integrase inhibitor approved for treatment of HIV-infected patients harboring multiresistant viruses.

2010-01-01

372

Clinical significance of unilateral sinusitis.  

UK PubMed Central (United Kingdom)

In general, the etiologic factors of chronic paranasal sinusitis are systemic conditions such as nutrition, predisposition, allergy, and local factors such as nasal anatomic conditions. Among these...Full Text Available

1986-09-01

373

Clinical Investigation Program, Reports Control Symbol MED ...  

Science.gov (United States)

... POG Cook, BA A Case Control Study of Childhood 147 8552(85) Rhabdomyosarcoma (0) POG COOK, BA Phase II Study of 6-Mercaptopurine ...

1988-10-01

374

Cardiac Angiosarcoma-Associated Membranoproliferative Glomerulonephropathy  

UK PubMed Central (United Kingdom)

Primary cardiac angiosarcoma is a rare cardiac tumor. The initial clinical course is often asymptomatic, and metastatic disease is present in a majority of affected patients at diagnosis. We present...Full Text Available

2011-01-01

375

CRC manual of nuclear medicine: Procedures. Fourth Edition  

Energy Technology Data Exchange (ETDEWEB)

This book discusses the procedures applied for the clinical nuclear medicine laboratory. The procedures are presented as proven guidelines. The chapters are included on quality assurance, radionuclide handling, and radiation safety.

1983-01-01

376

Bullet injuries of the brain  

UK PubMed Central (United Kingdom)

Experience gained with a wide variety of missile injuries of the brain is presented. Clinical signs and intracranial pressure (ICP) studied in the early post-injury period have been correlated with...Full Text Available

1974-09-01

377

Breast cancer in the elderly.  

UK PubMed Central (United Kingdom)

Breast cancer in the elderly has attracted considerable interest in recent years for three main reasons. Firstly, information concerning the profile (clinical and biological) of the disease in the geriatric...Full Text Available

1995-11-01

378

Bone scanning in Ewing's sarcoma  

International Nuclear Information System (INIS)

In eight patients with Ewing's sarcoma bone scans were performed using "9"9"mTc-MDP. This procedure rendered possible the diagnosis of clinically or radiologically silent metastases. (orig.).

379

Bacterial flora-typing with targeted, chip-based Pyrosequencing  

UK PubMed Central (United Kingdom)

BackgroundThe metagenomic analysis of microbial communities holds the potential to improve our understanding of the role of microbes in clinical conditions. Recent, dramatic improvements...Full Text Available

380

Automated Pharmacy Patient Medication Profiling System  

UK PubMed Central (United Kingdom)

The Systems Development Group and the Pharmacy Service of the Washington D.C. VAMC are involved in automating the administrative and clinical data requirements of a satellite out-patient pharmacy....Full Text Available

1981-11-04

381

Animal Models for Radiation Injury, Protection and Therapy  

Science.gov (United States)

... radiation during clinical therapy and exposures due to radiation accidents or attacks, in which the doses are uncontrolled ... only be used off-label in victims of radiation accidents or attacks. The idea...

382

A teleconferencing system.  

UK PubMed Central (United Kingdom)

Training of health professionals commonly involves multiple sites in order to best utilize the available clinical material. However, this makes it difficult to achieve continuity in the presentation...Full Text Available

1993-01-01

383

A Transposon and Transposase System for Human Application  

UK PubMed Central (United Kingdom)

The stable introduction of therapeutic transgenes into human cells can be accomplished using viral and nonviral approaches. Transduction with clinical-grade recombinant viruses offers the potential...Full Text Available

2010-04-01

384

A Review of the Pharmacology and Clinical Uses of Ivermectin  

UK PubMed Central (United Kingdom)

The avermectins were introduced in 1981 and constitute a potent new class of anthelmintic agents. They are naturally-derived products of microbial action displaying an exceptionally wide range of antiparasitic...Full Text Available

1987-08-01

385

A Novel Tool for the Assessment of Pain: Validation in Low Back Pain  

UK PubMed Central (United Kingdom)

BackgroundAdequate pain assessment is critical for evaluating the efficacy of analgesic treatment in clinical practice and during the development of new therapies. Yet the currently...Full Text Available

2009-04-01

386

"Paratrigeminal" paralysis of the oculopupillary sympathetic system  

UK PubMed Central (United Kingdom)

Raeder described five patients with mixed features of trigeminal nerve pathology and oculosympathetic impairment, with or without other cranial nerve lesions. This constellation of clinical features...Full Text Available

2002-03-01

387

Fiscal 1997 report on the results of the R and D of industrial scientific technology. R and D of synergistic ceramics (R and D of corrosion prevention technology for the petroleum production system); 1997 nendo sangyo kagaku gijutsu kenkyu kaihatsu seika hokokusho. Synergy ceramics no kenkyu kaihatsu (sekiyu seisan system fushoku boshi gijutsu kenkyu kaihatsu)  

Energy Technology Data Exchange (ETDEWEB)

To heighten durability and safety of materials/parts for undersea oil drilling, the development of ceramic base materials was made by developing function harmony type process technology which harmonizes on a high grade contrary characteristics and various functions. The paper summed up the fiscal 1997 results. In the design of system formation, computational simulation technology was developed to the composite process and the diploid system. The development of multifunction simultaneous manifestation materials was trially made by the higher nano structure process. A study was made of control of microstructures of porous materials and matrix filling by the gas phase precipitation control. Proposed were selective control of grain growth from species crystals and the columnar particle orientation laminated structure of simultaneous manifestation of strength and toughness. By composite precipitation reaction control, studied were simultaneous ...

1998-03-01

388

Effective equivalent dose and radiation risk in radionuclide diagnostics estimated in patients of the Nuclear Medicine Department of the Medical Academy 'Carl Gustav Carus' Dresden  

International Nuclear Information System (INIS)

7,959 patients were examined by radionuclide in-vivo methods within one year, 1,228 of them by application of "1"3"1I-iodide (radioiodine test and scintigraphy of the thyroid gland). In compliance with the ICRP publications 26 and 27 the somatically effective equivalent dose H/sub s,eff/ was ascertained for several examining methods, derived from it the collective dose S/sub s,eff/ and considering a part of manifestation resulting from the age distribution of patients, the somatic risk regarding radiation-induced malignoma with fatal termination. For the patients examined by "1"3"1I-iodide the collective dose was 79.9 man x Sv and the mean somatic risk 30 x 10"-"5 with a part of manifestation of 0.39 accordig to 0.37 radiation-induced malignomas with fatal termination. For all patients examined by other radiopharmaceuticals the collective dose was 14.07 man x Sv, the mean somatic risk 1.7 x 10"-"5 according to 0.11 malignomas. The average ...

1986-01-01

389

Variability of the physical properties of tuff at Yucca Mountain, NV  

Energy Technology Data Exchange (ETDEWEB)

Lateral and vertical variabilities in the bulk and mechanical properties of silicic volcanic tuff at the potential nuclear waste repository site in Yucca Mountain, NV have been evaluated. Laboratory measurements have been performed on tuff specimens recovered from boreholes located to support the design of the Exploratory Studies Facility/North Ramp. The data include dry and saturated bulk densities, average grain density, porosity, compressional and shear wave velocities, elastic moduli, and compressional and tensional fracture strengths. Data from eight boreholes aligned in a northwest-southeast direction have been collected under the required quality assurance program. Three boreholes have penetrated the potential repository horizon. The information collected provides for an accurate appraisal of the variability of rock properties in the vicinity of the boreholes. As expected, there is substantial variability in the bulk ...

1994-12-31

390

Polyp measurement based on CT colonography and colonoscopy: variability and systematic differences  

Energy Technology Data Exchange (ETDEWEB)

To assess the variability and systematic differences in polyp measurements on optical colonoscopy and CT colonography. Gastroenterologists measured 51 polyps by visual estimation, forceps comparison and linear probe. CT colonography observers randomly assessed polyp size two-dimensionally (abdominal and intermediate window) and three-dimensionally (manually and semi-automatically). Linear mixed models were used to assess the variability and systematic differences between CT colonography and optical colonoscopy techniques. The variability of forceps and linear probe measurements was comparable and both showed less variability than measurement by visual assessment. Measurements by linear probe were 0.7 mm smaller than measurements by visual assessment or by forceps. The variability of all CT colonography techniques was lower than for measurements by forceps or visual assessment and ...

2010-06-15

391

CT in the study of thoracic-pulmonary complications after liver transplantation  

International Nuclear Information System (INIS)

In this article is reviewed the role of Computed Tomography (CT) in thoracic complications following ortho topic liver transplantation (OLT). In a post-OLT population of 567 patients transplanted in the Italian institutions, 100 patients (17.6%) were examined with chest CT. It was reviewed data relative to the total number of examinations, clinical and/or radiographic indications, the CT technique-i.e., conventional (with (out) intravenous, i.v., contrast material) or high-resolution (HRCT). It also reviewed the radiologic patterns and their correlation with the other clinical, bronchoscopic and/or laboratory results. Of 152 chest CT examinations, 45 (29.6%) were performed because of clinical indications, 31 (20.4%) because of a radiographic abnormality, 64 (42.1%) because of clinical and radiographic abnormality, 64 (42.1%) because of clinical and radiographic indications, while in ...

2000-12-01

392

The effects of temperature dependent viscosity and thermal conductivity on unsteady MHD convective heat transfer past a semi-infinite vertical porous moving plate with variable suction  

British Library Electronic Table of Contents (United Kingdom)

In this article, we studied the effects of variable viscosity and thermal conductivity on an unsteady two-dimensional laminar flow of a viscous incompressible conducting fluid past a semi-infinite vertical porous moving plate taking into account the effect of a magnetic field in the presence of variable suction. The fluid viscosity is assumed to vary as an inverse linear function of temperature but the thermal conductivity is assumed to vary as a linear function of temperature. It is assumed that the porous plate moves with a constant velocity in the direction of fluid flow, and the free stream velocity follows the exponentially increasing small perturbation law. The governing equations for the flow are transformed into a system of nonlinear ordinary differential equations by perturbation ...

2007-01-01

393

The coexistence of fish species in streams: relationships between assemblage attributes and trophic and environmental variables  

British Library Electronic Table of Contents (United Kingdom)

Diet overlap and niche breadth are well-known species traits from trophic ecology that can assist in explaining how species interact and coexist as well as the ecological mechanisms that influence biodiversity. In the present study, we analyzed the relationships between these trophic variables and indicators of resource availability with some attributes of fish assemblages (species richness, Shannon diversity index, evenness, density and individual body size). The physical and chemical characteristics of the biotopes (topography, water quality and conservation of slopes) were examined to identify possible patterns. Monthly sampling using electrofishing was conducted in 2003 along five streams located in the Cuiab? River watershed. The relationships between environmental variables and attri...

2011-01-01

394

Powertrain and apparatus using a continuously variable ratio transmission to improve fuel economy  

Energy Technology Data Exchange (ETDEWEB)

An automotive powertrain includes a conventional piston engine, a continuously variable ratio transmission, an engine speed sensor and a feedback control system. The control system adjusts both the transmission ratio and the throttle valve in the engine carburetor or fuel metering system in response to the position of the accelerator pedal and in response to the crankshaft speed as measured by the engine sensor. The transmission provides extreme overdrive gear ratios which allow the engine to be operated at wide open throttle even during moderate cruising, and, in addition, the engine carburetor or fuel metering system is calibrated to deliver to the engine a stoichiometric air-fuel mixture which is combined, before combustion, with a special proportion of recirculated exhaust gas. As a result of extensive wide open throttle engine operation with the above mentioned intake charge composition, combustion variables are optimized to produce ...

1981-07-28

395

Power correlation for vertical axis wind turbines with varying geometries  

British Library Electronic Table of Contents (United Kingdom)

Abstract In this paper, a new predictive model that can forecast the performance of a vertical axis wind turbine (VAWT) is presented. The new model includes four primary variables (rotor velocity, wind velocity, air density, and turbine power output) as well as five geometrical variables (rotor radius, turbine height, turbine width, stator spacing, and stator angle). These variables are reduced to include the power coefficient (Cp) and tip speed ratio (TSR). A power coefficient correlation for a novel VAWT (called a Zephyr Vertical axis Wind Turbine (ZVWT)) is developed. The turbine is an adaptation of the Savonius design. The new correlation can predict the turbine's performance for altered stator geometry and varying operating conditions. Numerical simulations with a rotating reference f...

2011-01-01

396

Long and Short Distance Migration in Italy: The Role of Economic, Social and Environmental Characteristics  

British Library Electronic Table of Contents (United Kingdom)

This paper analyses Italian interregional migration flows. The approach taken is to decompose labour mobility flows into short distance and long distance migration and to model the effects of economic variables, social capital and quality of life variables, and amenity variables, on the mobility behaviour of individuals. We estimate these different types of migration flows using a negative binomial model, augmented with instruments to control for potential endogeneity issues. Our findings demonstrate that long distance migration reflects a disequilibrium model of migration whereas short distance migration largely reflects an equilibrium model of migration. As such, attempts to model interregional migration in general will be mis-specified as the simultaneously-operating underlying mobility...

2011-01-01

397

Irreversible Performance of a Quantum Harmonic Heat Engine  

CERN Document Server

The unavoidable irreversible losses of power in a heat engine are found to be of quantum origin. Following thermodynamic tradition a model quantum heat engine operating by the Otto cycle is analyzed. The working medium of the model is composed of an ensemble of harmonic oscillators. A link is established between the quantum observables and thermodynamical variables based on the concept of canonical invariance. These quantum variables are sufficient to determine the state of the system and with it all thermodynamical variables. Conditions for optimal work, power and entropy production show that maximum power is a compromise between the quasistatic limit of adiabatic following on the compression and expansion branches and a sudden limit of very short time allocation to these branches. At high temperatures and quasistatic operating conditions the efficiency at maximum power coincides with the endoreversible result. The optimal ...

2006-01-01

398

Interannual relationships between Indian Summer Monsoon and Indo-Pacific coupled modes of variability during recent decades  

British Library Electronic Table of Contents (United Kingdom)

Various SST indices in the Indo-Pacific region have been proposed in the literature in light of a long-range seasonal forecasting of the Indian Summer Monsoon (ISM). However, the dynamics associated with these different indices have never been compared in detail. To this end, the present work re-examines the variabilities of ISM rainfall, onset and withdrawal dates at interannual timescales and explores their relationships with El Ni?o-Southern Oscillation (ENSO) and various modes of coupled variability in the Indian Ocean. Based on recent findings in the literature, five SST indices are considered here: Ni?o3.4 SST index in December?January both preceding [Nino(?1)] and following the ISM [Nino(0)], South East Indian Ocean (SEIO) SST in February?March, the Indian Ocean Basin (IOB) mode in ...

2011-01-01

399

Experiences in batch trajectory alignment for pharmaceutical process improvement through multivariate latent variable modelling  

British Library Electronic Table of Contents (United Kingdom)

The primary objective of batch data as trajectory alignment (or synchronization) is to standardize the data sampling per batch according to the evolution of the process, and secondarily to homogenize the samples per run. The use of an indicator variable performs both objectives well. Two examples from the pharmaceutical sector are discussed to illustrate the different ways to deal with uneven samples across batches and across variables in the same batch. Since trajectory alignment requires large time investment, a simple triage approach is proposed to assess the need to analyze the dynamics of a given process and hence perform alignment. The presented examples are representative of a broad variety of batch processes that are operated by recipe in the pharmaceutical sector. In our experienc...

2011-01-01

400

Enamel-Calibrated Lamellar Bone Reveals Long Period Growth Rate Variability in Humans  

British Library Electronic Table of Contents (United Kingdom)

Abstract Mammalian teeth exhibit incremental structures representing successive forming fronts of enamel at varying time scales, including a short daily increment called a cross striation and a long period called a stria of Retzius, the latter of which, in humans, occurs on average every 8-9 days. The number of daily increments between striae is called the repeat interval, which is the same period as that required to form one increment of bone, i.e. the lamella, the fundamental - if not archetypal - unit of bone. Lamellae of known formation time nevertheless vary in width, and thus their measures provide time-calibrated growth rate variability. We measured growth rate variability for as many as 6 years of continuously forming primary incremental lamellar bone from midshaft femur histologic...

2011-01-01

401

Dirichlet mean identities and laws of a class of subordinators  

CERN Document Server

An interesting line of research is the investigation of the laws of random variables known as Dirichlet means. However, there is not much information on interrelationships between different Dirichlet means. Here, we introduce two distributional operations, one of which consists of multiplying a mean functional by an independent beta random variable, the other being an operation involving an exponential change of measure. These operations identify relationships between different means and their densities. This allows one to use the often considerable analytic work on obtaining results for one Dirichlet mean to obtain results for an entire family of otherwise seemingly unrelated Dirichlet means. Additionally, it allows one to obtain explicit densities for the related class of random variables that have generalized gamma convolution distributions and the finite-dimensional distribution of their associated L\\'{e}vy processes. ...

2010-01-01

402

Combined inverse modeling approach and load duration curve method for variable nitrogen total maximum daily load development in an agricultural watershed  

British Library Electronic Table of Contents (United Kingdom)

Purpose Nonpoint sources (NPS) pollution has been an important cause for water quality impairment worldwide. To take the temporal variations of both NPS pollution and in-stream attenuation into consideration, an inverse modeling approach and the load duration curve (LDC) method were combined for variable nutrient total maximum daily load (TMDL) development. Methods Water quality and hydrological parameters were monitored monthly along the ChangLe River system in 2004?2008. The catchment NPS export load (EL) and TMDL for total nitrogen (TN) were estimated by the inverse format of an existing stream nutrient transport equation. The LDC method was used to describe the variability of EL, TMDL, requiring load (RLR) and percent (the ratio between the RLR and the EL, RPR) reduction, and then to s...

2011-01-01

403

Characterizing the time variability in magnetized neutrino--cooled accretion disks: signatures of the gamma-ray burst central engine  

CERN Document Server

The central engine of Gamma Ray Bursts is hidden from direct probing with photons mainly due to the high densities involved. Inferences on their properties are thus made from their cosmological setting, energetics, low-energy counterparts and variability. If GRBs are powered by hypercritical accretion onto compact objects, on small spatial scales the flow will exhibit fluctuations, which could in principle be reflected in the power output of the central engine and ultimately in the high energy prompt emission. Here we address this issue by characterizing the variability in neutrino cooled accretion flows through local shearing box simulations with magnetic fields, and then convolving them on a global scale with large scale dynamical simulations of accretion disks. The resulting signature is characteristic, and sensitive to the details of the cooling mechanism, providing in principle a discriminant for GRB central engine properties.

2010-01-01

404

Centennial climate variability in the British Isles during the mid-late Holocene  

British Library Electronic Table of Contents (United Kingdom)

Multi-millennial climate changes were relatively minor over the mid-late Holocene in the British Isles, because orbitally forced insolation changes were smaller than those at higher latitudes. Centennial climate variability is thus likely to have exerted a greater influence on the environment and human society of the region. Proxy-climate records from the British Isles covering the last 4500years are assembled and re-evaluated with the aim of identifying centennial climate variability reflected by multi-proxy indicators. The proxies include bog oak populations, peatland surface wetness, flooding episodes from fluvial deposits, speleothem annual band width and oxygen isotopes, chironomids from lake sediments and sand and dune deposition. Most proxies reflect water balance rather than temper...

2010-01-01

405

Assessing variability of water quality in a groundwater-fed perennial lake of Kashmir Himalayas using linear geostatistics  

British Library Electronic Table of Contents (United Kingdom)

This paper presents a study on Manasbal lake, which is one of the high altitude lakes in the Kashmir Valley, India. Eighteen water samples were analysed for major ions and trace elements to assess the variability of water quality of the lake for various purposes. Geostatistics, the theory of regionalized variables, was then used to enhance the dataset and estimate some missing spatial values. Results indicated that the concentration of major ions in the water samples in winter was higher than in summer. The scatter diagrams suggested the dominance of alkaline earths over the alkali elements. Three types of water were identified in the lake that are referred to as Ca?HCO3, Mg?HCO3 and hybrid types. The lake water was found to be controlled by rock?water interaction with carbonate lithology ...

2011-01-01

406

Advanced experimental design applied to damage tolerance of composite materials  

Science.gov (United States)

This paper focuses on a factorial-based design strategy. The approach provides an efficient and statistically reliable means for assessing the influence of multivariable effects. It is applied to the detection and evaluation of damage in impacted composite sandwich panels. The experimental results obtained from this test strategy are utilized to form an empirical response function. The resulting polynomial relates damage area to residual compression strength at values of independent variables for which testing did not occur. The response function also identifies nonlinear interaction effects of key variabes that cannot be easily ascertained by traditional single-variable test strategies. Independent variables evaluated include core thickness, number of face sheet plys and impact energy. The methodology presented allows the designer to predict with more confidence the damage tolerance of a composite material component, and ...

1991-01-01

407

A variable gene delivery carrier-biotinylated chitosan/polyethyleneimine  

International Nuclear Information System (INIS)

A variable gene delivery system has been developed based on conjugating chitosan to biotin through a functionalized poly(ethylene glycol) (PEG) spacer, which can be used to further bind different molecules on the outer layer of a polymer/DNA complex by streptavidin (SA)-biotin linkage. In this study, TAT-conjugated SA was used as the model molecule to prove the conjugation function of the prepared complex. In addition, low-molecular-weight poly(ethyleneimine) (PEI) was added into the polymer/DNA complex to increase the transfection efficiency. The results of the luciferase assay show that the transfection efficiency of the prepared complex was significantly correlated with the amount of PEI and was further enhanced when TAT was conjugated to the complex by SA-biotin linkage. Considered to have negligible cytotoxic effects, the variable gene delivery complex prepared in this study would be of considerable potential as carriers for in vitro ...

2010-12-01

408

A study on the pretreatment of a sugarcane bagasse sample with dilute sulfuric acid  

British Library Electronic Table of Contents (United Kingdom)

Experiments based on a 23 central composite full factorial design were carried out in 200-ml stainless-steel containers to study the pretreatment, with dilute sulfuric acid, of a sugarcane bagasse sample obtained from a local sugar?alcohol mill. The independent variables selected for study were temperature, varied from 112.5?C to 157.5?C, residence time, varied from 5.0 to 35.0 min, and sulfuric acid concentration, varied from 0.0% to 3.0% (w/v). Bagasse loading of 15% (w/w) was used in all experiments. Statistical analysis of the experimental results showed that all three independent variables significantly influenced the response variables, namely the bagasse solubilization, efficiency of xylose recovery in the hemicellulosic hydrolysate, efficiency of cellulose enzymatic saccharificatio...

2011-01-01

409

Radiotherapy quality assurance review in a multi-center randomized trial of limited-disease small cell lung cancer: the Japan Clinical Oncology Group (JCOG) trial 0202  

UK PubMed Central (United Kingdom)

BackgroundThe purpose of this study was to analyze the radiotherapy (RT) quality assurance (QA) assessment in Japan Clinical Oncology Group (JCOG) 0202, which was the first trial...Full Text Available

410

New mechanism for methicillin resistance in Staphylococcus aureus: clinical isolates that lack the PBP 2a gene and contain normal penicillin-binding proteins with modified penicillin-binding capacity.  

UK PubMed Central (United Kingdom)

Seventeen clinical isolates of Staphylococcus aureus (from the United States and Europe) selected for low (borderline)-level methicillin resistance (MIC of methicillin, 2 to 4 micrograms/ml; MIC of...Full Text Available

1989-11-01

411

Monoclonal antibody imaging in malignant and benign gastrointestinal diseases  

International Nuclear Information System (INIS)

The "1"3"1I-labelled monoclonal antibodies 791T/36 and 79IT/36 Fab fragments have been evaluated in the imaging of patients with colorectal cancer, with benign colorectal tumours, and with malignant tumours of other parts of the gastrointestinal tract. The results of clinical imaging have been carefully correlated with clinical findings and direct measurement of the preferential uptake of antibody by the tumours. (UK).

412

Interventional MR imaging: Clinical results obtained with a 1.5 Tesla system  

International Nuclear Information System (INIS)

The clinical feasibility of using interventional examination techniques was tested with an equipment combining fluoroscopy and MR imaging. This hybrid system showed to be of advantage in a great number of interventional examinations. The 1.5 Tesla magnet proved to be superior to open MR scanning systems in terms of image quality and scanning times. (orig.).

413

Instrument of millimetre wave radiation and its effect on malignant tumor in mice and its application in clinic  

Energy Technology Data Exchange (ETDEWEB)

An animated test is made for mice with malignant tumors irradiated by a self-made millimetre wave radiator for medical purpose. It is observed that S-180 sarcomas in mice after irradiation has been distinctly suppressed. And remarkable effects are shown through a lot of clinical practices on peptic ulcer, skin-deep ulcer, acute and chromic soft tissue injuries etc.

1995-12-31

414

Importance of computer tomography in paediatric diagnostics of abdominal and pelvic tumours  

Energy Technology Data Exchange (ETDEWEB)

In a joint study conducted by the University Clinic of Radiology, Graz, and the Medical University Clinic, Innsbruck, the results of computer tomography examinations of the abdomen and pelvis in 23 cases of tumours in children are discussed. In children computer tomography resents special difficulties on account of the very poorly developed fatty layers between the organs and the increased incidence of movement artifacts. The importance of computer tomography for the diagnosis of abdominal and pelvic tumours is discussed.

1980-03-01

415

Health care of the elderly at Tygerberg Geriatric Clinic and Goodwood Aftercare Hospital.  

Science.gov (United States)

Comprehensive geriatric care should receive nation-wide attention in order to realize its objectives. An analysis of patient problems at the Geriatirc Clinic, Tygerberg Hospital and Goodwood Aftercare Hospital is presented. The training of personnel, with full motivation of the community, to render health services to the aged is discussed. PMID:7368010

1980-03-29

416

Evaluation on the clinical effect of lysozyme chloride in radiotherapy  

Energy Technology Data Exchange (ETDEWEB)

Lysozyme chloride was administered to 84 patients of laryngeal cancer and the clinical effect was discussed. Lysozyme chloride delayed the appearance of swelling and white plaque while it accelerated that of inflammatory erythema in radiotherapy. No difference of the local inflammation was found between lysozyme administered groups and not administered groups when irradiation and chemotherapy were combined. Any side effect was not seen in blood picture of all cases by using lysozyme chloride.

1982-10-01

417

Disagreements between central clinical events committee and site investigator assessments of myocardial infarction endpoints in an international clinical trial: review of the PURSUIT study  

UK PubMed Central (United Kingdom)

BackgroundLimited information has been published regarding how specific processes for event adjudication can affect event rates in trials. We reviewed nonfatal myocardial infarctions...Full Text Available

2001-01-01

418

Clinical translation of ultraviolet autofluorescence microscopy towards endomicroscopy for early detection of cancer  

Science.gov (United States)

The non-invasiveness of autofluorescence technology may reduce sampling error and time delay for histopathology diagnosis. We establish biophotonic methods and guidelines to visualize and interpret early epithelial tissue changes that signify disease. Flexible and rigid fiber endomicroscopy instrumentation design parameters feasible for translation towards clinical use are in development.

2010-12-01

419

Clinical application of FCR for the portable chest radiographs in ICU  

Energy Technology Data Exchange (ETDEWEB)

The diagnostic value of the portable chest radiography obtained with Fuji computed radiography (FCR) was evaluated in comparison with conventional images in 23 patients who were admitted to ICU in Yokohama City University Hospital. On the whole , FCR produced more exellent images than conventional screen-film radiographs. Especially the evaluation for the demonstration of the catheters, the endotracheal tubes and the tracheal shadows obtained high score. We discuss the clinically utility of FCR for the portable chest radiographs in ICU. (author).

1989-08-01

420

Clinical application of FCR for the portable chest radiographs in ICU  

International Nuclear Information System (INIS)

The diagnostic value of the portable chest radiography obtained with Fuji computed radiography (FCR) was evaluated in comparison with conventional images in 23 patients who were admitted to ICU in Yokohama City University Hospital. On the whole , FCR produced more exellent images than conventional screen-film radiographs. Especially the evaluation for the demonstration of the catheters, the endotracheal tubes and the tracheal shadows obtained high score. We discuss the clinically utility of FCR for the portable chest radiographs in ICU. (author).

1989-01-01

421

Clinical and metabolic consequences of two regimens of total parenteral nutrition in the newborn  

UK PubMed Central (United Kingdom)

The clinical and metabolic effects of two regimens of total parenteral nutrition delivering the same amino-acid (2·8 g/kig per 24 h), fat (4·8 g/kg per 24 h), and glucose (12 g/kg per...Full Text Available

1983-03-01

422

Clinical Procedures for Medical Technology Specialists  

CERN Document Server

Divided into diagnostic and treatment sections, this book provides a comprehensive overview of the most common medical procedures performed in modern clinical settings. Each section presents common names for the procedure; an outline of the disease or injury for which the procedure is performed; a brief review of the anatomical structures and physiological processes that are involved; staffing, equipment, and pre-procedure requirements; a detailed description of the procedure itself; and, a discussion of expected outcomes as well as potential complications. Each chapter includes a summary and

2010-01-01

423

Characteristics of CDC group 1 and group 1-like coryneform bacteria isolated from clinical specimens.  

UK PubMed Central (United Kingdom)

Fifteen strains of CDC group 1 coryneform and biochemically similar bacteria were isolated from clinical specimens. Of the 15 strains isolated, 11 were derived from abscesses and purulent lesions, mostly...Full Text Available

1993-11-01

424

A prospective evaluation of the safety and efficacy of the TAXUS Element paclitaxel-eluting coronary stent system for the treatment of de novo coronary artery lesions: Design and statistical methods of the PERSEUS clinical program  

UK PubMed Central (United Kingdom)

BackgroundPaclitaxel-eluting stents decrease angiographic and clinical restenosis following percutaneous coronary intervention compared to bare metal stents. TAXUS Element is a third-generation...Full Text Available

425

A pragmatic study exploring the prevention of delirium among hospitalized older hip fracture patients: Applying evidence to routine clinical practice using clinical decision support  

UK PubMed Central (United Kingdom)

Delirium occurs in up to 65% of older hip fracture patients. Developing delirium in hospital has been associated with a variety of adverse outcomes. Trials have shown that multi-component preventive...Full Text Available

426

6. Workshop on heavy-charged particles in biology and medicine. Book of abstracts  

Energy Technology Data Exchange (ETDEWEB)

Topics of this proceedings are: DNA damage and repair; Space research; Cell and tissue radiobiology; Treatment planning 1: The role of clinical RBEs; Treatment planning 2: Dose optimization and inverse planning; Dosimetry; Clinical results of particle therapy and new techniques; Status reports and future developments. Separate abstracts were prepared for 79 chapters. (orig./SR)

1997-09-01

427

Computed radiography in X-ray examination of stomach. Evaluation by phantom experiments and clinical studies  

Energy Technology Data Exchange (ETDEWEB)

The usefulness and clinical applicability of computed radiography(FCR) in X-ray examination of the stomach were evaluated in comparison with film-screen (FS) radiography by both phantom experiments and clinical studies. Receiver operating characteristic (ROC) curve analysis consisting of 25 normal and 25 artificially created simulated lesions on an orginally created Styrofoam phantom showed no difference in lesion detectability between FCR and FS radiography. Both were also equal in evaluation of the internal structure and margin of the 25 lesions by visual ranking. ROC curve analysis of clinical cases was performed in 30 cases, 20 normal and 10 abnormal, while evaluation by visual ranking was performed on 18 lesions. There was no significant difference between FCR and FS radiography either with ROC curve analysis or visual ranking, although the variations were somewhat greater in the clinical cases ...

1995-08-01

428

Computed radiography in X-ray examination of stomach. Evaluation by phantom experiments and clinical studies  

International Nuclear Information System (INIS)

The usefulness and clinical applicability of computed radiography(FCR) in X-ray examination of the stomach were evaluated in comparison with film-screen (FS) radiography by both phantom experiments and clinical studies. Receiver operating characteristic (ROC) curve analysis consisting of 25 normal and 25 artificially created simulated lesions on an orginally created Styrofoam phantom showed no difference in lesion detectability between FCR and FS radiography. Both were also equal in evaluation of the internal structure and margin of the 25 lesions by visual ranking. ROC curve analysis of clinical cases was performed in 30 cases, 20 normal and 10 abnormal, while evaluation by visual ranking was performed on 18 lesions. There was no significant difference between FCR and FS radiography either with ROC curve analysis or visual ranking, although the variations were somewhat greater in the clinical cases ...

1995-01-01

429

Water Deficit and Spatial Pattern of Leaf Development. Variability in Responses Can Be Simulated Using a Simple Model of Leaf Development1  

UK PubMed Central (United Kingdom)

We analyzed the effect of short-term water deficits at different periods of sunflower (Helianthus annuus L.) leaf development on the spatial and temporal patterns of tissue expansion...Full Text Available

1999-02-01

430

Variable domain I of nematode CLEs directs post-translational targeting of CLE peptides to the extracellular space  

UK PubMed Central (United Kingdom)

Effector proteins expressed in the esophageal gland cells of cyst nematodes are delivered into plant cells through a hollow, protrusible stylet. Although evidence indicates that effector proteins function...Full Text Available

2010-12-01

431

Transposable elements are enriched within or in close proximity to xenobiotic-metabolizing cytochrome P450 genes  

UK PubMed Central (United Kingdom)

BackgroundTransposons, i.e. transposable elements (TEs), are the major internal spontaneous mutation agents for the variability of eukaryotic genomes. To address the general issue...Full Text Available

432

Transport of sorbing solutes in randomly heterogeneous formations: Spatial moments, macrodispersion, and parameter uncertainty  

Energy Technology Data Exchange (ETDEWEB)

Expressions for the spatial moments and macrodispersion tensor for sorbing solutes in heterogeneous formations were presented using a probabilistic model of a fluid residence time coupled with the particle position analysis. The fluid residence time was defined as a fraction of the actual time during which the particle stayed in the mobile fluid phase of the aquifer. The fluid residence time is a random variable whose variability comes as a result of the non-equilibrium sorption properties. The sorbing solute was assumed to be governed with first-order linear kinetics. The closed-form expressions were based on the stationarity in the kinetic process and on the first-order approximation in the hydraulic conductivity field and in the fluid residence time. The non-equilibrium effects were presented as a function of the spatial variability in hydraulic conductivity and temporal variability in the fluid ...

1993-06-01

433

Time-Referenced Effects of an Internal vs. External Focus of Attention on Muscular Activity and Compensatory Variability  

UK PubMed Central (United Kingdom)

The paralysis-by-analysis phenomenon, i.e., attending to the execution of one's movement impairs performance, has gathered a lot of attention over recent years (see Wulf, 2007,...Full Text Available

434

The Interaction between AID and CIB1 Is Nonessential for Antibody Gene Diversification by Gene Conversion or Class Switch Recombination  

UK PubMed Central (United Kingdom)

Activation-induced deaminase (AID) initiates somatic hypermutation, gene conversion and class switch recombination by deaminating variable and switch region DNA cytidines to uridines. AID is predominantly...Full Text Available

435

Temporal Stability of Urinary and Plasma Biomarkers of Tobacco Smoke Exposure among Cigarette Smokers  

UK PubMed Central (United Kingdom)

Intraindividual variability of measurements of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), nicotine, cotinine, and r-1,t-2,3,c-4-tetrahydroxy-1,2,3,4-tetrahydrophenanthrene...Full Text Available

2010-06-01

436

Seasonal and Spatial Variability of Bacterial and Archaeal Assemblages in the Coastal Waters near Anvers Island, Antarctica  

UK PubMed Central (United Kingdom)

A previous report of high levels of members of the domain Archaea in Antarctic coastal waters prompted us to investigate the ecology of Antarctic planktonic prokaryotes. rRNA hybridization...Full Text Available

1998-07-01

437

Relationship between mRNA secondary structure and sequence variability in Chloroplast genes: possible life history implications  

UK PubMed Central (United Kingdom)

BackgroundSynonymous sites are freer to vary because of redundancy in genetic code. Messenger RNA secondary structure restricts this freedom, as revealed by previous findings in...Full Text Available

438

RESPONSE LATENCY AS AN INDEX OF RESPONSE STRENGTH DURING FUNCTIONAL ANALYSES OF PROBLEM BEHAVIOR  

UK PubMed Central (United Kingdom)

Dependent variables in research on problem behavior typically are based on measures of response repetition, but these measures may be problematic when behavior poses high risk or when its occurrence...Full Text Available

2011-01-01

439

QOI10/477: The medCERTAIN Project: Rating and certification of Internet health information using medPICS  

UK PubMed Central (United Kingdom)

IntroductionHealth information on the Internet undergoes no quality control at the stage of production, thus its quality is highly variable, making it difficult...Full Text Available

440

Predictors of disability in a longitudinal sample of patients with rheumatoid arthritis.  

UK PubMed Central (United Kingdom)

Information from the Health Assessment Questionnaire (HAQ) is used to identify which variables measured in 1981 successfully predict the severity of disease in 1989 and the eight year change in severity...Full Text Available

1992-05-01

441

Practical Applications of the Bioinformatics Toolbox for Narrowing Quantitative Trait Loci  

UK PubMed Central (United Kingdom)

Dissecting the genes involved in complex traits can be confounded by multiple factors, including extensive epistatic interactions among genes, the involvement of epigenetic regulators, and the variable...Full Text Available

2008-12-01

442

Post traumatic stress symptoms and heart rate variability in Bihar flood survivors following yoga: a randomized controlled study  

UK PubMed Central (United Kingdom)

BackgroundAn earlier study showed that a week of yoga practice was useful in stress management after a natural calamity. Due to heavy rain and a rift on the banks of the Kosi river,...Full Text Available

443

OPTIMIZATION OF COMBINED SEWER OVERFLOW CONTROL SYSTEMS  

Science.gov (United States)

The highly variable and intermittent pollutant concentrations and flowrates associated with wet-weather events in combined sewersheds necessitates the use of storage-treatment systems to control pollution.An optimized combined-sewer-overflow (CSO) control system requires a manage...

444

Non-Detection of Polarized, Scattered Light from the HD 189733b Hot Jupiter  

CERN Document Server

Using the POLISH instrument, I am unable to reproduce the large-amplitude polarimetric observations of Berdyugina et al. (2008) to the >99.99% confidence level. I observe no significant polarimetric variability in the HD 189733 system, and the upper limit to variability from the exoplanet is Delta_P < 7.9 x 10^(-5) with 99% confidence in the 400 nm to 675 nm wavelength range. Berdyugina et al. (2008) report polarized, scattered light from the atmosphere of the HD 189733b hot Jupiter with an amplitude of two parts in 10^4. Such a large amplitude is over an order of magnitude larger than expected given a geometric albedo similar to other hot Jupiters. However, my non-detection of polarimetric variability phase-locked to the orbital period of the exoplanet, and the lack of any significant variability, shows that the polarimetric modulation reported by Berdyugina et al. (2008) cannot be due to the ...

2009-01-01

445

Monitoring the Simultaneous Presentation of Spatialized Speech Signals in a Virtual Acoustic Environment.  

Science.gov (United States)

The effect of spatial auditory information on a listener's ability to detect, identify, and monitor multiple simultaneous speech signals was evaluated using virtual audio technology. Factorial combinations of three variables - the number of localized spee...

1998-01-01

446

Molecular dynamics of a ?B DNA element: base flipping via cross-strand intercalative stacking in a microsecond-scale simulation  

UK PubMed Central (United Kingdom)

The sequence-dependent structural variability and conformational dynamics of DNA play pivotal roles in many biological milieus, such as in the site-specific binding of transcription factors to target...Full Text Available

2008-09-01

447

Investigating the spatial variability in incidence of coronary heart disease in the Gazel cohort: the impact of area socioeconomic position and mediating role of risk factors  

UK PubMed Central (United Kingdom)

Study objectiveThe study aim was to improve our understanding of the relationships between contextual socioeconomic characteristics and coronary heart disease (CHD)...Full Text Available

2011-02-01

448

Industrial emissions cause extreme urban ozone diurnal variability  

UK PubMed Central (United Kingdom)

Simulations with a regional chemical transport model show that anthropogenic emissions of volatile organic compounds and nitrogen oxides (NOx = NO + NO2) lead to a dramatic diurnal...Full Text Available

2004-04-27

449

Incorporation of the International Spinal Cord Injury Data Set Elements into the National Institute of Neurological Disorders and Stroke (NINDS) Common Data Elements (CDEs)  

UK PubMed Central (United Kingdom)

ObjectiveTo develop consistent variable names and a common database structure for the data elements in the International Spinal Cord Injury (SCI) Data Sets.Full Text Available

2011-01-01

450

Identification of genes and haplotypes that predict rheumatoid arthritis using random forests  

UK PubMed Central (United Kingdom)

Random forest (RF) analysis of genetic data does not require specification of the mode of inheritance, and provides measures of variable importance that incorporate interaction effects. In this paper...Full Text Available

451

Human variability and susceptibility to trichloroethylene.  

UK PubMed Central (United Kingdom)

Although humans vary in their response to chemicals, comprehensive measures of susceptibility have generally not been incorporated into human risk assessment. The U.S. EPA dose-response-based risk assessments...Full Text Available

2000-05-01

452

Hominin life history: reconstruction and evolution  

UK PubMed Central (United Kingdom)

In this review we attempt to reconstruct the evolutionary history of hominin life history from extant and fossil evidence. We utilize demographic life history theory and distinguish life history variables,...Full Text Available

2008-04-01

453

High genetic variability and low local diversity in a population of arbuscular mycorrhizal fungi  

UK PubMed Central (United Kingdom)

Arbuscular mycorrhizal fungi (AMF) are ecologically important root symbionts of most terrestrial plants. Ecological studies of AMF have concentrated on differences between species; largely assuming...Full Text Available

2004-02-24

454

High Speed Cylindrical Roller Bearing Development.  

Science.gov (United States)

High speed experimental tests provided data on six parametric cylindrical roller bearings. Four bearing variables were evaluated and the results were correlated with the analytical model developed under Naval Air Propulsion Center Contract N00140-76-C-038...

1980-01-01

455

Heats (enthalpies) of formation of coals and the thermodynamic evaluation of the coal formation process  

British Library Electronic Table of Contents (United Kingdom)

An approach to the calculation of the quantity of heat consumed in the process of coal formation is presented. The variability of this parameter in a coalification series is analyzed using coals from the Kuznetsk and Tunguska Basins as an example.

2011-01-01

456

Hamiltonian BRST formalism for gauge-invariant systems with closed algebra  

International Nuclear Information System (INIS)

The systems for which the algebra of gauge transformations in the lagrangian formalism is closed, are considered. The hamiltonian BRST charge and the BRST-invariant hamiltonian are found explicitly. Their expansions in powers of the ghost variables contain, in general, an infinite number of terms. (orig.).

1991-11-01

457

Genome-wide linkage scan for contraction velocity characteristics of knee musculature in the Leuven Genes for Muscular Strength Study  

UK PubMed Central (United Kingdom)

The torque-velocity relationship is known to be affected by ageing, decreasing its protective role in the prevention of falls. Interindividual variability in this torque-velocity relationship is partly...Full Text Available

2008-09-01

458

Genome size and wing parameters in passerine birds  

UK PubMed Central (United Kingdom)

Despite their status as the most speciose group of terrestrial vertebrates, birds exhibit the smallest and least variable genome sizes among tetrapods. It has been suggested that this is because powered...Full Text Available

2009-01-07

459

Genetic architecture of voluntary exercise in an advanced intercross line of mice  

UK PubMed Central (United Kingdom)

Exercise is essential for health, yet the amount, duration, and intensity that individuals engage in are strikingly variable, even under prescription. Our focus was to identify the locations and effects...Full Text Available

2010-07-01

460

Feature Selection and Classification of MAQC-II Breast Cancer and Multiple Myeloma Microarray Gene Expression Data  

UK PubMed Central (United Kingdom)

Microarray data has a high dimension of variables but available datasets usually have only a small number of samples, thereby making the study of such datasets interesting and challenging. In the task...Full Text Available

461

Experimental evaluation of angularly-variable fiber geometry for targeting depth-resolved reflectance from layered epithelial tissue phantoms  

Science.gov (United States)

The aim of the present study focuses on experimentally demonstrating the efficacy of using angularly-variable fiber geometry to achieve the desired tissue-layer selection and probing depths with the further objective of enhancing the sensitivity and specificity of spectral diagnosis in stratified architectures that resemble human cervical epithelia. The morphological and biochemical features of epithelial tissue vary in accordance with tissue depths; consequently, the accuracy of spectroscopic diagnosis of epithelial dysplasia may be enhanced by probing the optical properties of this tissue. When correlated to cellular dysplasia, layer-specific changes in tissue optical properties may be deciphered by reflectance spectroscopy coupled with angularly-variable fiber geometry. This study addresses the utility of using such angularly-variable fiber geometry for resolving spatially-specific spectral signatures of tissue ...

2007-03-01

462

Effect of Wastewater Treatment Plant Effluent on Microbial Function and Community Structure in the Sediment of a Freshwater Stream with Variable Seasonal Flow?  

UK PubMed Central (United Kingdom)

We investigated the effects of wastewater treatment plant (WWTP) discharge on the ecology of bacterial communities in the sediment of a small, low-gradient stream in South Australia. The quantification...Full Text Available

2008-05-01

463

EFFECT OF THE DIGENEAN PARASITE PROTEROMETRA MACROSTOMA ON HOST MORPHOLOGY IN THE FRESHWATER SNAIL ELIMIA LIVESCENS  

Science.gov (United States)

... 1984; Martin-Mora et al., 1995), and parasitism (Rothschild and Rothschild, 1939; Pesigan et al., 1958; Moose, 1963; Pan, ... effects of digeneans are variable; they may enhance (Rothschild and Rothschild...

464

Do the Obese Have Lower Body Temperatures? A New Look at a Forgotten Variable in Energy Balance  

UK PubMed Central (United Kingdom)

Understanding the pathogenesis of obesity is now more important than ever, given the remarkable world-wide epidemic. This paper explores the potential role of core temperature in energy balance, and...Full Text Available

2009-01-01

465

Dimensionless energy confinement scaling in W7-AS  

International Nuclear Information System (INIS)

Energy confinement in W7-AS has been analyzed in terms of dimensionally exact form free functions employing Bayesian probability theory. The confinement function was set up as a linear combination of dimensionally exact power law terms as already proposed very early by Connor and Taylor. Generation of this expansion basis is dictated by the basic plasma model which one assumes. Based upon data accumulated in W7-AS, which contains the energy content for a wide variety of variable settings, predictions for single variable scans are made. The scaling functions for density and power scans, respectively, are in quantitative agreement with data collected in W7-AS. The result of a single variable scan is therefore already hidden in the data obtained for arbitrary variable choices and can be extracted from the latter by a proper data analysis. Furthermore, the optimal model for the description of the global ...

1999-12-01

466

Detrended Fluctuation Analysis of Intracranial Pressure Predicts Outcome Following Traumatic Brain Injury  

UK PubMed Central (United Kingdom)

Detrended fluctuation analysis (DFA) is a recently developed technique suitable for describing scaling behavior of variability in physiological signals. The purpose of this study is to explore...Full Text Available

2008-11-01

467

Determinants of output in group and solo medical practice.  

UK PubMed Central (United Kingdom)

Certain structural and environmental factors other than technical combination of resources and firm size are hypothesized to affect medical practice output. Four groups of variables related to physician...Full Text Available

1976-01-01

468

Determinants of health insurance ownership among South African women  

UK PubMed Central (United Kingdom)

BackgroundStudies conducted in developed countries using economic models show that individual- and household- level variables are important determinants of health insurance ownership....Full Text Available

469

Climate models and scenarios  

Energy Technology Data Exchange (ETDEWEB)

In recent years the modelling of interannual climate variability has been studied, the atmospheric energy and water cycles, and climate simulations with the ECHAM3 model. In addition, the climate simulations of several models have been compared with special emphasis in the area of northern Europe

1996-12-31

470

Calibration of the solar UV radiometers in Finland  

Energy Technology Data Exchange (ETDEWEB)

In this report, the main emphasis is given to (1) the problems associated with the basic calibration of the spectroradiometer and (2) the year-to-year variability of the calibrations of the solar UV network radiometers. Also, the results from intercomparisons of the Brewer and OL 742 spectroradiometers are included

1996-12-31

471

CYP1B1 mutations in Spanish patients with primary congenital glaucoma: phenotypic and functional variability  

UK PubMed Central (United Kingdom)

PurposeTo analyze the contributions of cytochrome P4501B1 (CYP1B1) mutations to primary congenital glaucoma (PCG) in Spanish patients.MethodsWe...Full Text Available

472

Boundary value problem for an elliptic equation with rapidly oscillating coefficients in a rectangle  

British Library Electronic Table of Contents (United Kingdom)

An elliptic equation in a rectangle with coefficients depending on a fast variable and with its period being a small parameter is considered. An asymptotic expansion of the solution up to an arbitrary degree of the small parameter is constructed and substantiated by applying the two-scale expansion method.

2011-01-01

473

Average uncertainty as a determinant of observing behavior1  

UK PubMed Central (United Kingdom)

After discrimination training on a multiple variable-interval extinction schedule of food reinforcement, pigeons were placed on the uncued or mixed version of the same schedule and allowed to make...Full Text Available

1974-09-01

474

Automatic stenosis detection and quantification in renal arteriography.  

UK PubMed Central (United Kingdom)

Visual assessment of the degree of renal artery stenosis on renal arteriography has a large inter- and intraobserver variability. This degree is usually estimated by the ratio between the most narrowed...Full Text Available

1997-01-01

475

Assessing spatio-temporal variability of risk surfaces using residential history data in a case control study of breast cancer  

UK PubMed Central (United Kingdom)

BackgroundMost analyses of spatial clustering of disease have been based on either residence at the time of diagnosis or current residence. An underlying assumption in these analyses...Full Text Available

476

Aspirin and Clopidogrel Response Variability  

UK PubMed Central (United Kingdom)

Antiplatelet resistance has been proposed as a possible mechanism to explain recurrent cardiovascular events in patients who have coronary artery disease and who are undergoing dual antiplatelet therapy....Full Text Available

2008-01-01

477

Analytical study on analysis methods of several random variables for seismic nonlinear responses of reactor buildings  

International Nuclear Information System (INIS)

In the case wherein nonlinear seismic response analyses are carried out, the response values vary due to the variations in materials and modeling. In this paper, nonlinear analyses of several random variables are carried out using: i. a conventional method; ii. a two-point estimation method (i. and ii. are simplified methods); and iii. Monte Carlo simulation (detailed method) to examine the variability of the response in the excessive nonlinear range for seismic responses of shear walls. The analyses are performed to a PWR-3 loop type reactor building which is one of the most typical reactor buildings in Japan. The variations are considered in specified compressive strength of concrete, concrete damping factor, shear wave velocity of soil and shapes of shear stress-strain relation curves of shear walls. As the results by the two simplified methods closely matched the Monte Carlo simulation results, the appropriateness for applying the ...

1993-08-15

478

Absolute CD4+ T-Lymphocyte Count as a Surrogate Marker of Pediatric HIV Disease Progression  

UK PubMed Central (United Kingdom)

BackgroundTraditionally in pediatric HIV, the CD4+ T-lymphocyte percent is used in monitoring disease progression due to the variability in absolute CD4+ T-lymphocyte...Full Text Available

2008-07-01

479

A new evolutionary scenario for the Mycobacterium tuberculosis complex  

UK PubMed Central (United Kingdom)

The distribution of 20 variable regions resulting from insertion-deletion events in the genomes of the tubercle bacilli has been evaluated in a total of 100 strains of Mycobacterium tuberculosis,...Full Text Available

2002-03-19

480

A new VCAN/versican splice acceptor site mutation in a French Wagner family associated with vascular and inflammatory ocular features  

UK PubMed Central (United Kingdom)

PurposeTo detail the highly variable ocular phenotypes of a French family affected with an autosomal dominantly inherited vitreoretinopathy and to identify the disease gene.MethodsSixteen...Full Text Available

481

A Latent Variable Approach for Meta-Analysis of Gene Expression Data from Multiple Microarray Experiments  

UK PubMed Central (United Kingdom)

BackgroundWith the explosion in data generated using microarray technology by different investigators working on similar experiments, it is of interest to combine results across...Full Text Available

482

A Computational Framework Discovers New Copy Number Variants with Functional Importance  

UK PubMed Central (United Kingdom)

Structural variants which cause changes in copy numbers constitute an important component of genomic variability. They account for 0.7% of genomic differences in two individual genomes, of which...Full Text Available

483

Variable-dispersion electron spectrometer for the SCA/FEL  

International Nuclear Information System (INIS)

A variable-dispersion electron spectrometer is being installed for use by the Stanford Superconducting Accelerator in conjunction with its Free Electron Laser program. The system has been designed to operate with electron beam energies from 20 MeV to 200 MeV, with a maximum energy resolution of 0.01% FWHM. The maximum energy acceptance is approximately #+-# 5%, as determined by the bending magnet aperture. Resolution is controlled by adjusting the focal conditions at the entrance to a 90 degree bending magnet, while the dispersion is controlled by changing the magnitude and polarity of the field in a quadrupole magnet which immediately follows the bending magnet. 4 refs., 5 figs.

1989-06-01

484

United States Air Force Academy (USAFA) Vertical Axis Wind Turbine. Final report May 77-Sep 80  

Science.gov (United States)

This report describes the design, fabrication, installation and testing of a small variable-speed vertical axis wind turbine (VAWT). This VAWT is unique in its installation using hand tools only; unconventional and simple support system; and variable speed operation under microprocessor control. Initial testing confirmed that the turbine can be controlled by commanded alternator field modulation. Further studies will be directed toward determination of an optimum control algorithm.

1980-09-01

485

The effects of aircraft engine pollutant emission measurement variability on engine certification policy  

Science.gov (United States)

Divergence between aircraft engine emission regulations proposed by EPA and ICAO is discussed. Every engine, upon entering service, requires a certificate as to its compliance with emission standards. It is shown that despite the large variability in the measurements, it is possible to devise a certification procedure requiring the testing of one engine only. Statistical modeling of such a test at the 5% significance level is described. Values of the parameter standard deviation/mean recommended as certification standards for various pollutants are given. Features of a rational certification scheme to be formulated are outlined.

1978-10-01

486

Separation of variables for the quantum SL(2,R) spin chain  

CERN Document Server

We construct representation of the Separated Variables (SoV) for the quantum SL(2,R) Heisenberg closed spin chain and obtain the integral representation for the eigenfunctions of the model. We calculate explicitly the Sklyanin measure defining the scalar product in the SoV representation and demonstrate that the language of Feynman diagrams is extremely useful in establishing various properties of the model. The kernel of the unitary transformation to the SoV representation is described by the same "pyramid diagram" as appeared before in the SoV representation for the SL(2,C) spin magnet. We argue that this kernel is given by the product of the Baxter Q-operators projected onto a special reference state.

2003-01-01

487

Product identification in industrial batch fermentation using a variable forgetting factor  

British Library Electronic Table of Contents (United Kingdom)

For reliable operation and the optimization of production, industrial fermentation processes require appropriate tools for monitoring the process in real time. This work presents the structure and operation of a soft sensor for the on-line monitoring of biomass and product concentration during salinomycin and bacitracin fermentation in an industrial, 80-m^3 batch reactor; moreover it provides a tool for evaluation of batch production verified in industrial application. The process estimation algorithm consists of decoupled growth and product models, which ensures an unbiased convergence of the estimator and the robustness of the model. The production of secondary metabolites is described with a non-structured model upgraded with a variable forgetting factor that demonstrated a successful e...

2011-01-01

488

Method and system for controlling the idle speed of an internal combustion engine at variable ignition timing  

Energy Technology Data Exchange (ETDEWEB)

The idle speed of an internal combustion engine is controlled in response to a variable ignition timing control signal from a microcomputer. The microcomputer derives this control signal as a function of the magnitude of engine speed variation which occurs during engine idle periods to cause the ignition timing to vary quickly in response to a transitory engine load variation. An auxiliary air delivery system may be advantageously incorporated in the idle speed control system to cooperate with the ignition timing control in response to the engine speed variation.

1984-05-08

489

Less BOP running with variable bore rams  

Energy Technology Data Exchange (ETDEWEB)

The marine ram-type blowout preventer deployed from an offshore drilling rig has one serious disadvantage, its inaccessibility. A development to promote reliability of the subsea ram-type preventer and reduce the excess running and pulling to charge out rams, is the variable bare ram (VBR). Unlike the standard ram, the VBR has the ability to pack off a range of pipe sizes. Interest in VBR's has been revived and research and development in this equipment goes on at each of three manufacturer's facilities in Houston.

1984-04-01

490

Inclusive photoproduction of D{sup *{+-}} mesons at next-to-leading order in the general-mass variable-flavor-number scheme  

Energy Technology Data Exchange (ETDEWEB)

We discuss the inclusive production of D{sup *{+-}} mesons in {gamma}p collisions at DESY HERA, based on a calculation at next-to-leading order in the general-mass variable-flavor-number scheme. In this approach, MS subtraction is applied in such a way that large logarithmic corrections are resummed in universal parton distribution and fragmentation functions and finite mass terms are taken into account. We present detailed numerical results for a comparison with data obtained at HERA and discuss various sources of theoretical uncertainties. (orig.)

2009-02-15

491

Evolution of the white dwarf mass and spin in cataclysmic variables  

International Nuclear Information System (INIS)

We consider the spin-up of the white dwarf in non-magnetic cataclysmic variables (CVs) during secular evolution. If this is unresisted, CVs are quenched as boundary-layer emitters once the binary period has decreased by #approx# 1 hr. Angular momentum loss in nova explosions may, however, prevent the star reaching breakup. If the explosions remove (1 + #epsilon#) x the mass accreted between outbursts, values 0.5 < #approx# #epsilon# < #approx# 1 allow CVs to be modest boundary-layer emitters for most of their lifetimes. Spectral effects will limit their detection as soft X-ray sources. (author).

492

Energy productivity in the industrial sector: an econometric analysis  

Energy Technology Data Exchange (ETDEWEB)

Energy productivity and energy intensity within the industrial sector of the economy are examined. Results suggest that relative prices and other economic factors can explain much of the variation in both energy productivity and energy intensity for manufacturing and mining and for the industrial sector as a whole. Cyclical factors, seasonal factors and trend variables are also useful in explaining variation in these data, both for annual and monthly time series. Of the variables examined, it appears that the relative price of energy is a highly significant factor in accounting for the difference between actual industrial energy intensity and that which might have been expected had pre-1973 trends continued.

1983-01-01

493

Effects of variable hardness, ph, alkalinity, suspended clay, and humics on the chemical speciation and aquatic toxicity of copper  

Science.gov (United States)

The effects of variable hardness, pH, alkalinity, humics, and suspended clay on the chemical speciation of copper and its toxicity to fathead minnow larvae in Lake Superior water were investigated. Two proposed methods (toxicity factors and chemical speciation) for predicting LC50 values in specific natural waters from laboratory toxicity data and the average site specific values of general water quality parameters were evaluated. The accuracy of the cupric ion-selective electrode in determining CU/sup +2/ activities in ambient and chemically altered Lake Superior water was also determined.

1986-03-01

494

Coherent state quantum key distribution with multi letter phase-shift keying  

International Nuclear Information System (INIS)

We present a protocol for quantum key distribution using discrete modulation of coherent states of light. Information is encoded in the variable phase of coherent states which can be chosen from a regular discrete set ranging from binary to continuous modulation similar to phase-shift keying in classical communication. Information is decoded by simultaneous homodyne measurement of both quadratures and requires no active choice of basis. The protocol utilizes either direct or reverse reconciliation both with and without postselection. We analyze the security of the protocol and show how to enhance it by the optimal choice of all variable parameters of the quantum signal.

2010-05-01

495

Assessment of primary production and optical variability in shelf and slope waters near Cape Hatteras, North Carolina. Final project report  

Energy Technology Data Exchange (ETDEWEB)

In this project we determined primary production and optical variability in the shelf and slope waters off of Cape Hatteras, N.C. These processes were addressed in conjunction with other Ocean Margins Program investigators, during the Spring Transition period and during Summer. We found that there were significant differences in measured parameters between Spring and Summer, enabling us to develop seasonally specific carbon production and ecosystem models as well as seasonal and regional algorithm improvements for use in remote sensing applications.

2001-02-12

496

A finite-dimensional fermionic TQFT  

CERN Document Server

A fermionic - based on Grassmann--Berezin calculus of anticommuting variables - topological quantum field theory (TQFT) is considered, mainly in three dimensions. It is defined for piecewise-linear manifolds and, for a given triangulation, deals only with a finite number of variables. Despite its simple nature, it can distiguish between lens spaces L(7,1) and L(7,2). And despite its origin from a kind of Reidemeister torsion, it does this without using nontrivial representations of the fundamental group. Also, symbolic calculations are presented giving strong evidence of existence of similar theory in four dimensions.

2011-01-01

497

A comment on: ''The solution to the forward-bias puzzle''  

British Library Electronic Table of Contents (United Kingdom)

Pippenger (2011) recently proposed a solution to the longstanding forward-bias puzzle. He argues that the puzzling estimates obtained using the standard equation for the efficient markets hypothesis are due to omitted variable bias. He identifies the missing variables as the future change in the forward exchange rate and the future interest differential. When these are added to the standard equation, he finds a one-to-one relationship between the future change in the spot rate and the forward premium. However, we argue that his equation can only test covered interest parity and offers no insight into the forward-bias puzzle.

2011-01-01

498

Stochastic analysis of contaminant transport: One-dimensional non-reactive and reactive cases  

Energy Technology Data Exchange (ETDEWEB)

A reliability approach for probabilistic modeling of one-dimensional non-reactive and reactive transport in porous media provides two important quantitative results: (1) an estimate of the probability that dimensionless concentration equals or exceeds some specified level and, (2) the sensitivity of the probabilistic outcome to likely changes in each uncertain variable. The reliability approach is particularly attractive because it can incorporate various marginal probability density functions (PDF) for any of the uncertain variables. In this work uncertain variables include: groundwater flow velocity, diffusion coefficient, dispersivity, distribution coefficient, porosity and bulk density. The primary objective is to examine how the probabilistic outcome is influenced by choice of marginal PDF, correlation and magnitude of uncertainty for the variables. Because little information exists concerning the ...

1990-12-03

499

MR findings of central nervous system involvement in acquired immunodeficiency syndrome patient : a report of two cases  

Energy Technology Data Exchange (ETDEWEB)

Central nervous system (CNS) manifestations in acquired immunodeficiency syndrome (AIDS) patients are an early and common feature. The spectrum of AIDS-related CNS diseases are encephalitis caused by the human immunodeficiency virus(HIV) itself, opportunistic infection, infarct and malignancy. We experienced two cases of CNS involvement in AIDS and they were serologically diagnosed as HIV encephalitis and CNS toxoplasmosis, respectively. In the case of the HIV encephalitis patient, brain MRI showed a non-enhancing lesion with high signal intensity on T2WI and low signal on T1WI and there was no mass effect on the right frontal lobe, periventricular white matter, splenium of the corpus callosum or bilateral basal ganglia. In the other case of CNS toxoplasmosis, MR showed multiple nodular and rim enhanced mass lesions in the right basal ganglia, thalamus and periventricular white matter, which were of low signal intensity on T1WI and of high intensity on T2WI. We ...

1996-10-01

500

Disturbed tooth formation by /sup 60/Co-gamma-ray radiation  

Energy Technology Data Exchange (ETDEWEB)

The molar of guinea pigs was irradiated with /sup 60/Co-..gamma.. ray for daily observations of the manifestation of disturbed tooth formation by microradiography and the time registration by tetracycline-labelling. Irradiation first injured young blast cells of the dentin in the growth phase, dental pulp cells, and cells of the enamel. The portion composed of injured cells formed a depressed ''constriction'' from the dental pulp side toward the border between the enamel and dentin. The cells of the enamel injured by irradiation in the growth phase later formed a very thin irregular stroma. In contrast, cells in the differentiation or subsequent phase at the time of irradiation and cells probably having started to grow after irradiation proceeded with formation of a normal stroma and calcification. No uniform relation was obtained between the histological staining of the organic stroma of normal or abnormal dentin and ...

1982-02-01