variability biological: Topics by WorldWideScience.org

Dynamic neuronal ensembles: Issues in representing structure change in object-oriented, biologically-based brain models

... biological variability body distribution kidneys labelled compounds lead 203

2

Molecular dynamics of a ?B DNA element: base flipping via cross-strand intercalative stacking in a microsecond-scale simulation

This paper describes the structure of dynamic neuronal ensembles (DNEs). DNEs represent a new paradigm for learning, based on biological neural networks that use variable structures. We present a computational neural element that demonstrates biological neuron functionality such as neurotransmitter feedback absolute refractory period and multiple output potentials. More specifically, we will develop a network of neural elements that have the ability to dynamically strengthen, weaken, add and remove interconnections. We demonstrate that the DNE is capable of performing dynamic modifications to neuron connections and exhibiting biological neuron functionality. In addition to its applications for learning, DNEs provide an excellent environment for testing and analysis of biological neural systems. An example of habituation and hyper-sensitization in biological ...

1996-12-31

3

On the development of a new methodology for groundwater-driven health risk assessment

The sequence-dependent structural variability and conformational dynamics of DNA play pivotal roles in many biological milieus, such as in the site-specific binding of transcription factors to target...Full Text Available

2008-09-01

4

Prioritizing areas in the native range of hygrophila for surveys to collect biological control agents

A methodology and hypothetical case study are presented for incorporation of uncertainty and variability into calculations of human health risk appropriate for regional, or basin-scale, groundwater management problems. Uncertainty in well water concentration is introduced through complex contaminant migration patterns in the subsurface. Variability is considered in parameters related to individual behavior patterns and biological effects and to groundwater extraction and distribution networks. A joint uncertainty and variability (JUV) analysis is used to generate a two-dimensional distribution or risk surface that spans both transport uncertainty as well as individual variability. Cuts in this distributional surface (fractiles of variability and percentiles of uncertainty) are presented and discussed. Comparisons with alternative approaches based upon ...

1998-01-01

5

British Library Electronic Table of Contents (United Kingdom)

Native to Southeast Asia, Hygrophila polysperma is an invasive aquatic weed of lotic habitats in the southern United States and Mexico. An increase in the number of water bodies invaded by hygrophila since 1990 suggests that current methods employed to control this weed are inadequate. Classical biological control may be a viable option for long term regulation of hygrophila in the invaded range. In this study, we used the Maximum Entropy Species Distribution Model (MaxEnt) to prioritize climatically suitable native habitats in India and Bangladesh for conducting exploratory surveys to collect biological control agents. In total, 164 point occurrences from the United States and Mexico and 20 predictor variables, including 19 bioclimatic variables and altitude, were used to predict the nati...

2011-01-01

6

The Oak Ridge Y-12 Plant biological monitoring and abatement program for East Fork Poplar Creek

A Bayesian Bioeconometric Model of Invasive Species Control: The Case of the Hemlock Woolly Adelgid

In May 1985, a National Pollutant Discharge Elimination System permit was issued for the Oak Ridge Y-12 Plant, a nuclear weapons components production facility located in Oak Ridge, Tennessee, and operated by Martin Marietta Energy Systems, Inc., for the US Department of Energy. As a condition of the permit, a Biological Monitoring and Abatement Program (BMAP) was developed to demonstrate that the effluent limitations established for the Oak Ridge Y-12 Plant protect the classified uses of the receiving stream (East Fork Poplar Creek), in particular, the growth and propagation of fish and aquatic life, as designated by the Tennessee Department of Health and Environment. A second purpose for the BMAP is to document the ecological effects resulting from implementation of a water pollution control program that will include construction of nine new wastewater treatment facilities over the next 4 years. Because of the complex nature of the effluent discharged to East ...

1989-10-01

7

British Library Electronic Table of Contents (United Kingdom)

In this article we evaluate a US Forest Service plan to mitigate damages from an invasive insect on public, forested land. We develop a dynamic model of infestation and control to explicitly account for biological interactions, baseline conditions, and uncertainty, thus creating a more complete picture of policy impacts than a static cost benefit analysis could provide. We combine the results of the dynamic model with an empirical study of nonmarket forest benefits to create a bioeconomic model of ecosystem management. Estimating the empirical model in a Bayesian framework allows us to treat the economic coefficients of the dynamic model as random variables. We specify distributions for the biological parameters and examine the effects of both biological and economic uncertainty on the pre...

2011-01-01

8

Biological Surface-Active Substance

International Science & Technology Center (ISTC)

Development of biological preparation with surfactant activity

9

Modelling the impacts of weather and climate variability on crop productivity over a large area: A new super-ensemble-based probabilistic projection

British Library Electronic Table of Contents (United Kingdom)

Estimates of climate change impacts are plague with uncertainties from many physical, biological, and social-economic processes. Among the urgent research priorities, more comprehensive assessments of impacts that better represent the uncertainties are needed. Here, we develop a new super-ensemble-based probabilistic projection approach to account for the uncertainties from CO2 emission scenarios, climate change scenarios, and biophysical processes in impact assessment model. We demonstrate the approach in addressing the probabilistic changes of maize production in the North China Plain in future. The new process-based general crop model, MCWLA [Tao, F., Yokozawa, M. Zhang, Z., 2009. Modelling the impacts of weather and climate variability on crop productivity over a large area: a new proc...

2009-01-01

10

Hydrothermal faunal assemblages and habitat characterisation at the Eiffel Tower edifice (Lucky Strike, Mid-Atlantic Ridge)

British Library Electronic Table of Contents (United Kingdom)

Abstract The Eiffel Tower edifice is situated in the Lucky Strike hydrothermal vent field at a mean depth of 1690-m on the Mid-Atlantic Ridge (MAR). At this 11-m-high hydrothermal structure, different faunal assemblages, varying in visibly dominant species (mussels and shrimp), in mussel size and in density of mussel coverage, were sampled biologically and chemically. Temperature and sulphide (-S) were measured on the different types of mussel-based assemblages and on a shrimp-dominated assemblage. Temperature was used as a proxy for calculating total concentrations of CH4. Based on the physico-chemical measurements, two microhabitats were identified, corresponding to (i) a more variable habitat featuring the greatest fluctuations in environmental variables and (ii) a second, more stable, ...

2011-01-01

11

Bioinformatics in the information age

Spatial heterogeneity and ecological models. [Predation

There is a well-known story about the blind man examining the elephant: the part of the elephant examined determines his perception of the whole beast. Perhaps bioinformatics--the shotgun marriage between biology and mathematics, computer science, and engineering--is like an elephant that occupies a large chair in the scientific living room. Given the demand for and shortage of researchers with the computer skills to handle large volumes of biological data, where exactly does the bioinformatics elephant sit? There are probably many biologists who feel that a major product of this bioinformatics elephant is large piles of waste material. If you have tried to plow through Web sites and software packages in search of a specific tool for analyzing and collating large amounts of research data, you may well feel the same way. But there has been progress with major initiatives to develop more computing power, educate biologists about computers, ...

2000-02-01

12

Gastrointestinal absorption of alfalfa-bound plutonium-238 by rats and guinea pigs

The role of natural enemies in the regulation of populations is one of the major questions facing population ecologists. Simplification have led to two theoretical ways of incorporating the role of natural enemies in single ecological models: diffusion models and patch-type models. The predictions of the models are different because of the way variability is incorporated. Three equations are presented for diffusion models and one for patch models. Since the two types of models apply at different combinations of spatial and temporal scales, the right model(s) to choose for a particular study requires careful assessment. A continuing dialogue between experimentalists and theoreticians will lead to a better understanding of natural systems such as those that occur in biological control.

1990-04-01

13

Determination of pressure distribution in an aerated bed in a controlled pilot-scale compost reactor

Rats and guinea pigs were fed "2"3"8Pu either biologically incorporated into alfalfa (by growth of the plant on soil containing Pu) or added as a solution to alfalfa, or were gavaged with a Pu solution. Depending upon the plant material fed, there appeared to be a twofold increase in "2"3"8Pu-gut absorption by the rat and a two- to fourfold increase in the guinea pig as compared with absorption from the Pu solution. The data, though limited and variable, suggest that Pu bound to plant tissue may have higher gut absorptivity than inorganic Pu in both herbivorous and nonherbivorous rodents.

1977-05-01

14

The Biology of Phenolic Containing Vesicles

This study investigated the effectiveness of dealing with biological waste by composting. In particular, it examined the feasibility of recovering excess thermal energy produced in the process of composting biological waste in terms of mass and energy transport parameters required in the aerated compost bed. An experiment was performed in which a 100 dm{sup 3} adiabatic, leak-tight reactor equipped with a controlled aeration system was constructed to study the temperature and pressure distribution in the bed. Sensors were used to determine the amount and humidity of emitted gases under variable external physical conditions. The perforated bottom of the reactor allowed for bed aeration. As such, the humidity and heat were transported upwards, forced by the air pumped in and by natural convection. In terms of pressure distribution inside the composted and aerated bed, the study results showed that there were considerable ...

2010-07-01

15

ST-segment changes after direct current external cardioversion for atrial fibrillation. Incidence, characteristics and predictive factors

Full Text Available

2008-09-01

16

British Library Electronic Table of Contents (United Kingdom)

Background: Incidence, characteristics and predictive factors of transient ST-segment changes after DC shock are poorly known. Methods: 91 consecutive pts referred for external cardioversion of atrial fibrillation (AF) (61 men, 69+/-10yo) were prospectively included. The presence of ST elevation or depression was assessed on 12 lead-ECG immediately after the first DC shock. Correlations with DC shock characteristics (monophasic/biphasic and energy), clinical variables, echocardiographic parameters, biological parameters, medications, anesthesic drugs as well with morphological features were made. Results: 18 and 20 pts underwent 200J or 300J monophasic and 53 pts 200J biphasic DC shocks. We found an incidence of 48% for ST-segment changes: 35% for ST elevation and 13% for ST depression. ST...

2011-01-01

17

Prevalence and Incidence of HCV Infection among Vietnam Heroin Users with Recent Onset of Injection

British Library Electronic Table of Contents (United Kingdom)

HCV infection continues to spread at an alarming rate among IDU populations. The available evidence suggests that HCV is acquired relatively quickly following onset of injection. However, there are few prospective studies of HCV acquisition, particularly among IDU populations in resource-poor settings. A sample of young male heroin injectors with recent onset of injection (<4?years) was recruited in Hanoi, Vietnam for a prospective assessment of the early course of injection (n?=?179). Both behavioral and biological assessments (including detailed retrospective assessment of injection initiation) were conducted at baseline and repeated at 6-month intervals for a period of 16?months. Variables associated with HCV infection (p value?p value?=?0.0005). In multivariate logistic regression anal...

2010-01-01

18

Biosorption of Zn(II) by Thiobacillus ferrooxidans

The complexities of skeletal biology

There have been a number of studies considering the possibility of removing and recovering heavy metals from diluted solutions. These are due, principally, because of the commercial value of some metals as well as in the environmental impact caused by them. The traditional methods for removing have several disadvantages when metals are present in concentrations lower than 100 mg/l. Biosorption, which uses biological materials as adsorbents, has been considered as an alternative method. In this work, variables like pH and biomass chemical pretreatment have been studied for its effect on the capacity for zinc biosorption by Thiobacillus ferrooxidans. Also, studies to determinate the time for zinc adsorption were carried out. Results indicate that a capacity as high as 82.61 mg of Zn(II)/g of dry biomass can be obtained at a temperature of 25 C and that the biosorption process occurs in a time of 30 min. (orig.)

2000-06-01

19

The analysis of biological and environmental samples for lead by photon activation

For a long time, the skeleton was seen as an amorphous tissue of little biological interest. But

2003-01-01

20

Entomopathogenic Nematodes in Biological Control

... activation analysis biological materials bremsstrahlung environment lead lead

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21

International Science & Technology Center (ISTC)

Commercial Production and Development, in Entomopathogenic Nematodes in Biological Control

22

Biology and Monitoring of Diamondback Terrapins in the Chesapeake Bay

Research and development on inhalation toxicologic evaluation of red phosphorus/butyl rubber combustion products

... to maintaining healthy terrapin populations in the Chesapeake. Biology and Monitoring of Diamondback Terrapins in the Chesapeake ... ...

23

Validation of biological markers for quantitative risk assessment.

Combinations of exposure concentrations, durations and frequencies were tested in four-week inhalation exposures followed by two weeks of recovery to define the interactive effects of these variables on biologic responses and to select the most-sensitive biologic response parameters for the subsequent subchronic studies. Response surface modeling was used for the experimental design and statistical analysis of the data. Results of preliminary testing suggested that exposure duration and frequency did not have major effects. Subsequently, male and female Sprague-Dawley rats were exposed in separate studies to RP/BR aerosols ranging from 0.40 to 1.20 mg/1 or to filtered air for 2.25 hr/day on four days/week for four weeks. Test-atmosphere monitoring data demonstrated that aerosol concentrations were consistently within 4% of the target values and mean particle size ranged from 0.44-0.64 ..mu..m with mean sigma g's of ...

1984-12-01

24

How safe are the biologicals in treating asthma and rhinitis?

The evaluation of biological markers is recognized as necessary to the future of toxicology, epidemiology, and quantitative risk assessment. For biological markers to become widely accepted, their validity...Full Text Available

1991-01-01

25

Synthesis and biological evaluation of ABCD ring fragments of the kibdelones.

A number of biological agents are available or being investigated for the treatment of asthma and rhinitis. The safety profiles of these biologic agents, which may modify allergic and immunological...Full Text Available

26

Phorbol esters from croton oil chemical nature and biological activities

PMID:21370327

2011-02-18

27

Demineralization of Crab Shells by Chemical and Biological Treatments

Not Available

1967-01-01

28

Biological Markers as Predictors of Radiosensitivity in Syngeneic Murine Tumors

Full Text Available

2005-02-01

29

University of Central Lancashire - Facilities

Full Text Available

2006-06-01

30

Wastenet

...specialised laboratories for pharmaceutics, tissue culture and molecular biology Excellent Laboratory Facilities Tissue Culture Facilities Molecular Biology Laboratory ...

31

Spectroscopy, colorimetry, and biological chemistry in the nineteenth century.

Biology of the Rio Grande Border Region: A Bibliography

The development of colorimetry and spectroscopy in the nineteenth century is described. An account is given of the application of their techniques to biological chemistry during that period.

1981-03-01

32

Finite element model selection using Particle Swarm Optimization

BIOLOGY OF THE RIO GRANDE BORDER REGION: A BIBLIOGRAPHY Information and Technology Report USGS/BRD/ITR--1997- .....

33

Evaluating created wetlands through comparisons with natural wetlands

This paper proposes the application of particle swarm optimization (PSO) to the problem of finite element model (FEM) selection. This problem arises when a choice of the best model for a system has to be made from set of competing models, each developed a priori from engineering judgment. PSO is a population-based stochastic search algorithm inspired by the behaviour of biological entities in nature when they are foraging for resources. Each potentially correct model is represented as a particle that exhibits both individualistic and group behaviour. Each particle moves within the model search space looking for the best solution by updating the parameters values that define it. The most important step in the particle swarm algorithm is the method of representing models which should take into account the number, location and variables of parameters to be updated. One example structural system is used to show the applicability of PSO in finding ...

2009-01-01

34

Environmental monitoring at Kahe Point, Oahu, Hawaii for OTEC pilot-plant development

The report summarizes the evaluation and recommendations regarding an approach to wetland sampling and characterization developed by the Wetlands Research Program (WRP) at U.S. Environmental Protection Agency, Environmental Research Laboratory, Corvallis, OR. Between trials, team members discussed at length the methodology and field protocols and modified them to reflect the conditions and difficulties encountered in sampling herbaceous wetlands in urban areas of Florida. Major emphasis is placed on the appropriateness of measured variables for determining successful wetland re-creation. Numerous physical and biological parameters were measured and compared in the nine created and nine natural wetlands. Analysis of these data has shown some important similarities and differences between created and natural wetlands and lends insight into the complex questions surrounding wetland creation and the equivalency of created wetlands to naturally ...

1991-11-01

35

Patterns of blood pressure variability in normotensive and hypertensive rats.

Two 40 MWe Ocean Thermal Energy Conversion (OTEC) Pilot Plant programs are in the initial phase of development near Kahe Point, Oahu, Hawaii. The two options being examined are: (1) a shelf-seated artificial island, connected via a causeway to Oahu, using stainless steel heat exchangers, with the thermal resource enhanced by effluent from a near-by power plant, ammonia working fluid and biocide (chlorine) cleaning; and (2) a shelf mount tower 1 mile off shore using submerged aluminum heat exchangers, R-22 working fluid, and slurry cleaning with biocide (chlorine) backup. Environmental Technical Requirements are described including: siting criteria; environmental design, and operational criteria; thermal resource evaluation and variability; physical, chemical, and biological data requirements; and regulatory requirements. Due to siting, design, and operational differences the proposed two pilot plant options have individual environmental ...

1982-08-01

36

Interactions in multiple schedules: negative induction with squirrel monkeys1

Udgivelsesdato: 1995-Nov

1995-01-01

37

Forest genetics: research and application in Indian forestry

In Experiment I, lever pressing by squirrel monkeys was maintained under a sequence of variable-interval, multiple variable-interval variable-interval, and multiple variable-interval extinction schedules...Full Text Available

1978-11-01

38

Effects of injection systems and plastic mulches on distribution and emissions of cis- and trans-1,3-dichloropropene and chloropicrin.

Sufficient genetic diversity exists in Indian tree species to give large genetic gains. Improvement potential, using wild gene resources for selection and breeding is vast as there are over 244 genera and 400 forest tree species in India. Of these over 30 species and 22 genera are of outstanding forestry value. Selective genetic-variation can be lifted from wild populations, multiplied vegetatively or by seed, and planted with controlled germplasm sources. Among the Indian species no less than 74 reproduce by cutting, 11 by layers, 9 by grafting and buding and 104 by root suckers. More than 161 species coppice vigorously. Afforestation techniques of over 170 species have been worked out. Tree genetic approach of survey of natural variability, quick evaluation, selection, conservation multiplication and planting superior variability directly in the field can give immediate genetic gains. This article discusses genetic information on indigenous ...

1981-04-01

39

Underlying Principles of Natural Selection in Network Evolution: Systems Biology Approach

The concentration and distribution of a soil fumigant in the subsurface of field plots are two key factors in the determination of the fumigant efficacy. Subsurface concentrations of the biologically active compounds cis- and trans-1,3-dichloropropene (1,3-D) and chloropicrin (CP) were determined in soil at two adjacent injection traces and midpoint between the two traces in plastic-covered field beds after injection of the fumigant Telone C35 by conventional chisels or by a coulter rig (Avenger coulters). Two of the four beds were covered with metallic polyethylene film (MPE) and the remaining two were covered with virtually impermeable film (VIF). Three hours after chisel injection, concentrations of the three compounds at the two adjacent injection traces in the two beds were highly variable. Large concentrations of the compounds were detected at the side traces, whereas the compounds were not detected at the middle traces (bed centers) in ...

2007-06-02

40

Biologic Rhythms Derived from Siberian Mammoths' Hairs

Systems biology is a rapidly expanding field that integrates diverse areas of science such as physics, engineering, computer science, mathematics, and biology toward the goal of elucidating the underlying...Full Text Available

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41

Research - Keyword Index

Wastenet

...and biological processes acting on recruitment and post-recruitment EU-Agrinet - Project sheet: Biological performance testing methodology to evaluate the durability of plywood as a quality indicator ... Project sheet: Biological performance testing methodology to evaluate the durability of plywood as a quali EU-Agrinet - Project sheet: Genetic evaluation of European ...

42

Variable elimination in chemical reaction networks with mass action kinetics

Hair is preserved for millennia in permafrost; it enshrines a record of biologic rhythms and offers a glimpse at chronobiology as it was in extinct animals. Here we compare biologic rhythms gleaned...Full Text Available

43

The stability of biological standards

We consider chemical reaction networks taken with mass action kinetics. The steady states of such a system are solutions to a system of polynomial equations. Even for small systems the task of finding the solutions is daunting. We develop an algebraic framework and procedure for linear elimination of variables. The procedure reduces the variables in the system to a set of "core" variables by eliminating variables corresponding to a set of non-interacting species. The steady states are parameterized algebraically by the core variables, and a graphical condition is given for when a steady state with positive core variables necessarily have all variables positive. Further, we characterize graphically the sets of eliminated variables that are constrained by a conservation law and show that this conservation law takes a ...

2011-01-01

44

Suitability of a New Plant Invader as a Target for Biological Control in Florida

The authors emphasize the importance of stability in biological standards and discuss the steps taken to ensure the stability of International Standards and the theoretical basis of the various stability...Full Text Available

1956-01-01

45

Menstrual Cycle: Basic Biology

... L. Sutton. 2000. Is the aquatic weed hygrophila, Hygrophila polysperma (Polemoniales: Acanthaceae), a suitable target for classical biological ... ...

46

MODELING AND BIOLOGICAL CONTROL OF MOSQUITOES

The basic biology of the menstrual cycle is a complex, coordinated sequence of events involving the hypothalamus, anterior pituitary, ovary, and endometrium. The menstrual cycle with all its...Full Text Available

2008-01-01

47

Liver Carcinogenesis Unit

Models can be useful at many different levels when considering complex issues such as biological control of mosquitoes. At an early stage, exploratory models are valuable in exploring the characteristics...Full Text Available

2007-01-01

48

Kenai Fjords National Park Biological Resources Buffer Coverage

The Liver Carcinogenesis Section uses the modern technologies of molecular biology, cell biology, protein chemistry and genetics to investigate the biochemical and genetic pathways involved in human liver cancer.

49

Healthy aging and disease: role for telomere biology?

... a buffer of all biological resources in the Kenai Fjords National Park Area. Data from Alaska Fish ... ...

50

Genetics, Genomics, and Molecular Biology

Aging is a biological process that affects most cells, organisms and species. Human aging is associated with increased susceptibility to a variety of chronic diseases, including cardiovascular disease,...Full Text Available

2011-05-01

51

In vivo and in vitro evaluation of dota-lanreotide radiolabelled with gallium-67

Genetics, Genomics, and Molecular Biology USGS scientists develop and integrate new genetic and molecular techniques into systematic analyses to describe individuals and populations of fish .....

52

Synthetic Biology and Human Health: Potential Applications for Spaceflight

One of the refinements of modern Nuclear Medicine is the capacity of providing dynamic and kinetics images of the administered radiopharmaceutical, reproducing its transport mechanism, action sites, receptor binding and excretion route. With the continues technological advances new radiopharmaceuticals have been developed in order to express higher specificity and with higher characters of affinity between receptor/complex. One radiopharmaceutical is formed by a reagent or bio molecule that has in its structure a radioisotope, that has the objectives of carrying it to the organs of affinity or to benign or malign tumoral process. Somatostatin inhibits the growing and proliferation of several tumoral cells. Somatostatin analogs bind to somatostatic receptors that are expressed in different kind of neoplasia DOTA-LANREOTIDE (DOTALAN) is an octapeptide analog to somatostatin. The interest of labeling the bio conjugate with gallium-67 in Nuclear Medicine comes from its physical, chemical ...

53

Space Biology and Medicine

Human space travelers experience a unique environment that affects homeostasis and physiologic

2011-01-01

54

Radon concentration measurements in a radon chamber for biological treatment using track detectors

Volume IV is devoted to examining the medical and associated organizational measures used to

2004-01-01

55

Radiation Protection of the Organism (Selected Chapters)

Short communication.

1992-09-01

56

Novel Antidrugabuse Peptide

... biologically important compounds is sharply lowered with passage of the solutions to the cell an organ, where their sensitivity ...

1970-12-11

57

International Science & Technology Center (ISTC)

Natural Biologically Active HLDF6 Peptide as Potential Preparation for Correction of Different Drugabuse Forms

58

Mechanism of superoxide anion-radical reactions with some biologically important compounds in aqueous solutions

Mechanical-biological waste treatment as an alternative to thermal processes; MBA-Konzepte als Alternative zur thermischen Abfallbehandlung

Short note.

1989-08-21

59

Localization of "2"0"3Pb-chloride in myocardial infarction

No abstract prepared.

2001-09-01

60

Internalization of cholera toxin by different endocytic mechanisms

... AND NUCLEAR MEDICINE biological localization cardiovascular diseases

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61

Illuminating Cell Biology

Cell biology, clathrin, endocytosis, dynamin, caveolae, cholera toxin

2001-01-01

62

Fresh-water biology, by Henry Baldwin Ward ... and George Chandler Whipple ... with the collaboration of a staff of ...

NASA's Ames Research Center awarded Ciencia, Inc., a Small Business Innovation Research contract to

2002-01-01

63

European Society for Evolutionary Biology meeting. Tracing the common roots of antibiotic resistance.

Language: English ...

64

Determination of Shooting Distance from Deformation of the ...

PMID:21921169

2011-09-16

65

Chemical and biological aspects of an arabinogalactan from the medicinal herb Phyllanthus niruri (quebra-pedra)

... Descriptors : *TERMINAL BALLISTICS, *WOUND BALLISTICS, VELOCITY, CONVERSION, REPRINTS, TISSUES(BIOLOGY), MANUFACTURING ...

66

Biophotonics and Bone Biology

No abstract prepared.

2005-07-01

67

Biology-inspired Architecture for Situation Management

One of the more-serious side effects of extended space flight is an accelerated bone loss

2004-01-01

68

Biology of lichen communities in Antarctica.

Situation Management is a rapidly developing science combining new techniques for data collection

2006-01-01

69

Biology and The Future of Mars

-Ecophysiological and floristic study of the lichen communities in .... Plasticity of the Lichen Catillaria corymbosa in Different Microhabitats of the ...

70

Biological Control of Sclerotinia sclerotiorum Using Indigenous Chitinolytic Actinomycetes in Jordan

It is possible that at some time in the future we might recreate a habitable climate on Mars

2004-01-01

71

Proceedings of the CEMA reclamation workshop on creating wetlands in the oil sands : final report

Full Text Available

2006-06-01

72

Polymorphisms in fatty acid metabolism-related genes are associated with colorectal cancer risk

The Creating Wetlands in the Oil Sands Reclamation workshop was held to solicit expert views from leading authorities in a number of disciplines related to the creation and study of wetlands, as well as to investigate challenges in the creation of wetlands in reclaimed oil sands landscapes. This document provided a detailed transcript of each presentation and all discussions that followed. The workshop was divided into 5 sessions: (1) wetlands background information; (2) groundwater conditions and boreal wetlands; (3) creating wetland types; (4) wildlife in boreal wetlands and traditional environmental knowledge; and (5) treatment wetlands. An expert panel overview provided presentations on post-mining restoration of boreal landscapes in oil sands regions; the creation of fens, marshes and shallow water wetlands at oil sands sites and the restoration of damaged peatlands. A outline of the physical scale of the oil sands mining disturbances was provided during the first session, as well ...

2006-08-15

73

Nanoelectrospray high capacity ion trap multiple stage mass spectrometry for the structural analysis of human brain gangliosides

Colorectal cancer is the third most common malignant tumor and the fourth-leading cause of cancer death worldwide. The crucial role of fatty acids for a number of important biological processes suggests a more in depth analysis of inter-individual differences in fatty acid metabolizing genes as contributing factor to colon carcinogenesis. We examined the association between genetic variability in 43 fatty acid metabolism-related genes and colorectal risk in 1225 CRC cases and 2032 controls participating in the European Prospective Investigation into Cancer and Nutrition study. 392 single nucleotide polymorphisms were selected using pairwise tagging with an r(2) cutoff of 0.8 and a minor allele frequency of >5%. Conditional logistic regression models were used to estimate odds ratios and corresponding 95% confidence intervals. Haplotype analysis was performed using a generalized linear model framework. On the genotype level, HPGD, PLA2G6, and ...

2010-01-01

74

Genomic analysis of the symbiotic marine crenarchaeon, Cenarchaeumsymbiosum

Full text: A novel protocol based on electrospray ionization (ESI) multiple stage high capacity ion trap (HCT) mass spectrometry (MS) was developed for glycosphingolipidomic surveys. The method was optimized for detailed structural elucidation of human brain gangliosides and particularly applied to human hippocampus-associated structures. The multiple stage MS experiments allowed for a complete structural characterization of GM1 ganglioside species, which was achieved by elucidation of the oligosaccharide sequence, identification of the GM1 a structural isomer from the data upon sialic acid localization along the sugar backbone and determination of the d18:1/18:0 of fatty acid/sphingoid base composition of the ceramide moiety. The methodology developed here is of general practical applicability for glycolipids and represents a step forward in the implementation of the advanced and most modern MS methods in glycomics. Gangliosides are glycosphingolipids, which consist of a mono- to ...

2006-10-25

75

Effect of temperature on the development of Steinernema carpocapsae and Steinernema feltiae (Nematoda: Rhabditida) in liquid culture.

Crenarchaea are ubiquitous and abundant microbial constituents of soils, sediments, lakes and ocean waters, yet relatively little is known about their fundamental evolutionary, ecological, and physiological properties. To better describe the ubiquitous nonthermophilic Crenarchaea, we analyzed the genome sequence of one representative, the uncultivated sponge symbiont, Cenarchaeum symbiosum. C. symbiosum genotypes coinhabiting the same host partitioned into two dominant populations, corresponding to previously described a- and b-type ribosomal RNA variants. Although synthetic, overlapping a- and b-type ribotypes harbored significant genetic variability. A single tiling path comprising the dominant a-type genotype was assembled, and used to explore the biological properties of C. symbiosum and its planktonic relatives. Out of a total of 2,066 predicted open reading frames, 36% were more highly conserved with other Archaea. The remainder ...

2006-06-24

76

Combined chemotherapy and radiotherapy: from biology to bed-side

For commercial use of the entomopathogenic nematodes Steinernema carpocapsae and Steinernema feltiae in biological control of insect pests, they are produced in liquid culture on artificial media pre-incubated with their symbiotic bacteria Xenorhabdus nematophila and Xenorhabdus bovienii, respectively. After 1 day of the bacterial culture, nematode dauer juveniles (DJs) are inoculated, which recover development. The adult nematodes produce DJ offspring, which are harvested and can be sprayed. This study determined optimal temperatures to obtain high DJ progeny within a short process time. Temperatures assessed were 23 degrees C, 25 degrees C, 27 degrees C, and 29 degrees C for S. carpocapsae and 20 degrees C, 23 degrees C, 25 degrees C, and 27 degrees C for S. feltiae. The recovery of inoculated DJs was hardly affected and was reduced only in S. carpocapsae at 29 degrees C. The fecundity (eggs in uterus) in S. carpocapsae reached a maximum at 27 degrees C; whereas, ...

2009-05-20

77

[Fundamental biological model for trials of wound ballistics].

Combination of radiotherapy and chemotherapy (CRC) is actually one important way of research in oncology. Theoretical advantages are: (1) Spatial cooperation; (2) Additivity, which is only obtained if the toxicity of each modality are different; (3) Supra-additivity, which needs a rigorous in vitro definition; the only way to prove it is to make an isobologram analysis. This model has however, some limitations: qualitative variable could not be used, results could be different, depending on the cell line and isoeffect chosen...In fact, a supra-additivity was only demonstrated for cis platinum and etoposide. Interactions mechanisms were: (1) at the molecular level, creation of new lesions or inhibition of radiation lesions repair; (2) At the cellular level, either cytokinetic cooperation with S-phase dependent drugs, or synchronization for the drugs which blocked the cells in M-phase; (3) At the tissular level, reoxygenation, cycle redistribution. In clinical ...

78

Gastric stromal tumors. CT findings; Tumori stromali gastrici. Aspetti con Tomografia Computerizzata

The aim of our experiment was the testing of effects of common ammunition on usable and slightly accessible biological tissue thereby to create fundamental simple biological model for trials of wounded ballistic. Like objective tissue was elected biological material - pork and beef hind-limbs, pork head, pork bodily cavity. It was discovered that objective tissue is able to react to singles types of shots in all spectrum results namely simple smooth penetration wound as well as splintery fracture in dependence on kind of using ammunition. Pork hind-limb was evaluated like the most suitable biological material for given object. PMID:17172163

2006-10-01

79

Temporal and Spatial Variability of the TOMS Total Ozone; Global Trends and Profiles

Gastric stromal tumors are an ill-defined group of lesions arising from muscle wall cells and characterized by extremely variable biological patterns. Thanks to modern immunohistochemical and ultrastructural techniques, four main classes of these lesions have been identified, namely: (1) tumors with differentiation toward smooth muscle cells; (2) tumors with differentiation toward neural elements; (3) tumors with differentiation toward neural elements; (3) tumors with dual differentiation toward either cell type. It was investigated the yield of CT in diagnosing and characterizing gastric stromal tumors. It was retrospectively reviewed the CT findings of 38 patients (15 men and 23 women; mean age 51 years) with pathologically proven gastric stromal tumors, namely 31 of myoid origin, 4 of neural origin, 2 with both muscle and neural differentiation, 1 lacking differentiation with either cell type. The myoid tumors involved gastric fundus in 9/13 ...

2000-02-01

80

Seasonal variability of leaf area index and foliar nitrogen in contrasting dry-mesic tundras

Full Text Available

2005-04-01

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81

Seasonal Relationship between El Nino-Southern Oscillation and Hydrologic Variables in Korea

Udgivelsesdato: May 2009

2009-01-01

82

Optimal Design of a Variable-Speed Cam for Power Circuit Breaker

Full Text Available

2007-04-01

83

Inter-annual variability of a zooplankton community: the importance of summer concentrated rainfall in a regulated river ecosystem

Full Text Available

2001-12-01

84

Confrontation between stellar pulsation and evolution; Proceedings of the Conference (ASP Series, Vol. 11), Bologna, Italy, May 28-31, 1990

Full Text Available

2011-03-01

85

The strong associations between organism characteristics and network architecture

Attention is given to the folowing topics: population I and II variable stars; LP variables, the sun, and mass determination; and predegenerate and degenerate variables. Particular papers are presented on alternative evolutionary approaches to the absolute magnitude of the RR Lyrae variables; the evolution of the Cepheid stars; nonradial pulsations in rapidly rotating Delta Scuti stars; dynamical models of dust shells around Mira variables; and pulsations of central stars of planetary nebulae.

1990-05-28

86

The sensitivity of real-time PCR amplification targeting invasive Salmonella serovars in biological specimens

Understanding the dependence and interplay between architecture and function in biological networks has great relevance to disease progression, biological fabrication and biological systems in general. Recent research in complex systems and networks, presents methods to properly mine the architectural interdependence in networks. Guided by such work, we propose methods to associate organism characteristics with network topology by analyzing a large number of architectural patterns. We adopt an automated approach using 11 topological metrics from complex networks to characterize a collection of various kinds of biological networks. Principal component analysis and clustering allow us to extract the indispensable, independent and informative metrics. Using hierarchical linear modeling, we observe that organism characteristics associate with these metrics, surprisingly well. This work can serve as a ...

2009-01-01

87

Soluble epoxide hydrolase inhibition reveals novel biological functions of epoxyeicosatrienoic acids (EETs)

BackgroundPCR amplification for the detection of pathogens in biological material is generally considered a rapid and informative diagnostic technique. Invasive Salmonella...Full Text Available

88

Reproductive Success of Cavity-nesting Birds Breeding under High-voltage Powerlines

Early on, intriguing biological activities were found associated with the EETs using in vitro systems. Although the EETs other than the 5,6-isomer, are quite stable chemically,...Full Text Available

2007-01-01

89

Preparation and biological properties of a novel composite scaffold of nano-hydroxyapatite/chitosan/carboxymethyl cellulose for bone tissue engineering

... biological effects of electromagnetic fields (EMFs) produced by high-voltage transmission lines have come under intense scrutiny, mostly with respect ... biological effects of electromagnetic fields (EMFs...

90

Pore-forming toxins trigger shedding of receptors for interleukin 6 and lipopolysaccharide.

In this study, we report the physico-chemical and biological properties of a novel biodegradable composite scaffold made of nano-hydroxyapatite and natural derived polymers of chitosan and carboxymethyl...Full Text Available

91

Near Infrared Dyes as Lifetime Solvatochromic Probes for Micropolarity Measurements of Biological Systems

Cleavage of membrane-associated proteins with the release of biologically active macromolecules is an emerging theme in biology. However, little is known about the nature and regulation of the involved...Full Text Available

1996-07-23

92

Metabolic clearance of biologically active luteinizing hormone in man.

The polarity of biological mediums controls a host of physiological processes such as digestion, signaling, transportation, metabolism, and excretion. With the recent widespread use of near-infrared...Full Text Available

2007-10-15

93

Estimation of effective population sizes from data on genetic markers

The plasma metabolic clearance of biologically active luteinizing hormone (bioactive LH) was studied using the rat interstitial cell testosterone (RICT) bioassay in six hypogonadotropic men after single...Full Text Available

1986-04-01

94

Electron spin resonance studies of radiation effects in biological materials. An assessment of current and future research

The effective population size (N_e) is an important parameter in ecology, evolutionary biology and conservation biology. It is, however, notoriously difficult to estimate,...Full Text Available

2005-07-29

95

Effects of Collaborative Group Composition and Inquiry Instruction on Reasoning Gains and Achievement in Undergraduate Biology

Electron spin resonance spectroscopy can provide a powerful approach to the study of radiation effects in biological materials. This memorandum gives an overview of current and future research. (author).

1987-06-01

96

Effects of 3 biologic dressings on healing of cutaneous wounds on the limbs of horses

This study compared the effectiveness of collaborative group composition and instructional method on reasoning gains and achievement in college biology. Based on initial student reasoning ability (i.e.,...Full Text Available

2011-03-01

97

Core Synthesis Facility: Bridging the Gap between Chemistry and Biology

AbstractThree biologic dressings [split-thickness allogeneic skin (STS)], allogeneic peritoneum (P), and xenogenic porcine small intestinal submucosa (PSIS)] were...Full Text Available

2004-01-01

98

Coordination chemistry and biological activity of 5'-OH modified quinoline-B12 derivatives.

CF-23“The biggest stumbling block for biological sciences turned out to be synthetic organic chemistry” – Elias A. Zerhouni, Former NIH Director in Chemical...Full Text Available

2010-09-01

99

Computational approaches to discovering semantics in molecular biology

The consequences of structural modifications at the 5'-OH ribofuranotide moiety of quinoline modified B12 derivatives are discussed in regard of the coordination chemistry, the electrochemical properties and the biological behaviour of the compound. PMID:21850334

2011-08-18

100

C. elegans as a model for stem cell biology

One of the central questions of molecular biology is the discovery of the semantics of DNA. This discovery relies in a critical way on a variety of expensive computations. In order to solve these computations, both parallel computers and special-purpose hardware play a major role.

1989-07-01

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101

Biologically based pesticide dose estimates for children in an agricultural community.

We review the application of C. elegans as a model system to understand key aspects of stem cell biology. The only bona fide stem cells in C. elegans...Full Text Available

2010-05-01

102

Biological species is the only possible form of existence for higher organisms: the evolutionary meaning of sexual reproduction

Current pesticide health risk assessments in the United States require the characterization of aggregate exposure and cumulative risk in the setting of food tolerances. Biologic monitoring can aggregate...Full Text Available

2000-06-01

103

BFL: a node and edge betweenness based fast layout algorithm for large scale networks

Consistent holistic view of sexual species as the highest form of biological existence is presented. The Weismann's idea that sex and recombination provide the variation for the natural...Full Text Available

104

An Undergraduate Course to Bridge the Gap between Textbooks and Scientific Research

BackgroundNetwork visualization would serve as a useful first step for analysis. However, current graph layout algorithms for biological pathways are insensitive to biologically...Full Text Available

105

A Floristic Reconnaissance of Montane Environments in the Foja Mts. of Papua Province, Indonesia

This article reports on a one-semester Advanced Cell Biology course that endeavors to bridge the gap between gaining basic textbook knowledge about cell biology and learning to think and work as a researcher....Full Text Available

2011-03-01

106

Genomics - from Neanderthals to high-throughput sequencing

... A Rapid Biological Assessment of the Kaijende Highlands, Enga Province, Papua New Guinea. RAP Bulletin of Biological ... A Rapid Biodiversity Assessment of the Kaijende Highlands, Enga Province, Papua New...

107

Genetic Applications in Avian Conservation

A report on 'The Biology of Genomes' meeting, Cold Spring Harbor, USA, 10-14 May 2006.

2006-01-01

108

Effect of dietary constituents on the absorption of lead in the human

... structure along an elevational gradient in Hawaiian honeycreepers reveals contrasting evolutionary responses to avian malaria. BMC Evolutionary Biology 8: ... ...

109

Development of a motion analysis system using acceleration sensors for tennis and its evaluations

... biological effects body burden diet intestinal absorption lead lead 203 man

1983-03-01

110

British Library Electronic Table of Contents (United Kingdom)

The term biological motion is often used by researchers studying the patterns of movement generated by living forms and in sports. We studied a pattern recognition system of motion in sport using biological motion data. Biological motion data are acquired using a 3D motion capture system. However, 3D motion capture systems are very expensive. In this article, a biological motion capture system was built using acceleration sensors. Our proposed system uses the technique of Gaussian fitting and regression analysis. We tested our proposed system in pattern recognition of outdoor tennis and its evaluations.

2011-01-01

111

Comparison of Microbial Fungicides in Antagonistic Activities Related to the Biological Control of Phytophthora Blight in Chili Pepper Caused by Phytophthora capsici

Biology-Inspired Distributed Consensus in Massively-Deployed Sensor Networks

Full Text Available

2010-12-01

112

BIOMAGNETIC RESPONSE OF SIMPLE BIOLOGICAL ...

Promises of ubiquitous control of the physical environment by large-scale wireless sensor networks

2005-01-01

113

The loss of lead in biological materials following different drying and ashing procedures

... Examples include magnetic forming tools, magnetic shielding, magnetohydrodynamic propulsion systems, and various magnetic containment ...

1970-01-01

114

Physical mechanisms of biological molecular motors

The loss of lead in various kinds of biological materials after drying and ashing is studied by using "2"0"3Pb as tracer which is intravenously injected into mice. The experimental results show that although the oven ashing can be used for determining the lead in samples of lung, kidney, and liver, etc., the oxygen plasma and high pressure digestion are the most suitable methods for the determination of lead in biological materials. (author) 5 refs.; 2 tabs.

115

Neutrons in Biology. A satellite meeting of the IUPAB/EBSA biophysics congress

Biological motors generally fall into two categories: (1) those that convert chemical into mechanical energy via hydrolysis of a nucleoside triphosphate, usually adenosine triphosphate, regarded as life's chemical currency of energy and (2) membrane bound motors driven directly by an ion gradient and/or membrane potential. Here we argue that electrostatic interactions play a vital role for both types of motors and, therefore, the tools of physics can greatly contribute to understanding biological motors.

2009-03-01

116

Biological network analysis and comparison: mining new biological knowledge

This meeting focussed on the study of the structure and dynamics of biological molecules, with particular emphasis on neutron and complementary methods as well as related enabling technologies. The program covered biological problems that are being addressed by neutron scattering and those where there is the potential to do so in the future. This document provides the abstracts of the different presentations. (A.L.B.)

2005-07-01

117

British Library Electronic Table of Contents (United Kingdom)

The mechanisms underlying life machinery are still not completely understood. Something is known, something is ?probably? known, other things are still unknown. Scientists all over the world are working very hard to clarify the processes regulating the cell life cycle and bioinformaticians try to support them by developing specialized automated tools. Within the plethora of applications devoted to the study of life mechanisms, tools for the analysis and comparison of biological networks are catching the attention of many researchers. It is interesting to investigate why.

2011-01-01

118

Is uniform target dose possible in IMRT plans in the head and neck?

Variable Pathogenicity Determines Individual Lifespan in Caenorhabditis elegans

Purpose: Various published reports involving intensity-modulated radiotherapy (IMRT) plans developed using automated optimization (inverse planning) have demonstrated highly conformal plans. These reported conformal IMRT plans involve significant target dose inhomogeneity, including both overdosage and underdosage within the target volume. In this study, we demonstrate the development of optimized beamlet IMRT plans that satisfy rigorous dose homogeneity requirements for all target volumes (e.g., #+-#5%), while also sparing the parotids and other normal structures. Methods and Materials: The treatment plans of 15 patients with oropharyngeal cancer who were previously treated with forward-planned multisegmental IMRT were planned again using an automated optimization system developed in-house. The optimization system allows for variable sized beamlets computed using a three-dimensional convolution/superposition dose calculation and flexible cost functions derived ...

2002-04-01

119

Variability In Motor Learning: Relocating, Channeling and Reducing Noise

A common property of aging in all animals is that chronologically and genetically identical individuals age at different rates. To unveil mechanisms that influence aging variability, we identified markers...Full Text Available

2011-04-01

120

The Characterisation of Three Types of Genes that Overlie Copy Number Variable Regions

Variability in motor performance decreases with practice but is never entirely eliminated, due in part to inherent motor noise. The present study develops a method that quantifies how performers...Full Text Available

2009-02-01

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121

Numerical optimization of spherical variable-line-spacing grating X-ray spectrometers

BackgroundDue to the increased accuracy of Copy Number Variable region (CNV) break point mapping, it is now possible to say with a reasonable degree of confidence whether a gene...Full Text Available

122

Intra-Individual Variability in Alzheimer's Disease and Cognitive Aging: Definitions, Context, and Effect Sizes

Operation of an X-ray spectrometer based on a spherical variable-line-spacing (VLS) grating is analyzed using dedicated ray-tracing software allowing fast optimization of the grating parameters and...Full Text Available

2011-03-01

123

Guided Cell Migration on Microtextured Substrates with Variable Local Density and Anisotropy

Background/AimsTo explore different definitions of intra-individual variability (IIV) to summarize performance on commonly utilized cognitive tests (Mini Mental State Exam; Clock...Full Text Available

124

Considerable Variability in Platelet Activity among Patients with Coronary Artery Disease in Response to an Increased Maintenance Dose of Clopidogrel

This work reports the design of and experimentation with a topographically patterned cell culture substrate of variable local density and anisotropy as a facile and efficient platform to guide...Full Text Available

2009-02-06

125

Comparative optimism in models involving both classical clinical and gene expression information

BackgroundVariable platelet response to clopidogrel has been widely observed. Studies have shown that the mean aggregation response to clopidogrel can be changed...Full Text Available

2009-05-01

126

Adaptive Thresholding for Improving Sensitivity in Single-Trial Simultaneous EEG/fMRI

BackgroundIn cancer research, most clinical variables have already been investigated and are now well established. The use of transcriptomic variables has raised two problems: restricting...Full Text Available

127

Biological effects of electromagnetic radiation in the microwave range

A common approach used to fuse simultaneously recorded EEG and fMRI is to correlate trial-by-trial variability in the EEG, or variability of components derived therefrom, with the blood oxygenation...Full Text Available

128

The Climatological Characteristics of Monthly Precipitation over Han- and Nakdong-river Basins: Part I. Variability of Area Averaged Time Series

The book examines current experimental and clinical knowledge concerning the biological and biophysical effects of electromagnetic radiation, particularly that in the microwave range. The biophysical bases of the interaction of electromagnetic radiation with matter are reviewed with emphasis on biological systems, and the effects of radiation on critical biological systems, including the nervous, reproductive, visual and blood-forming systems are compared. Data concerning the lethal effects of nonionizing radiation is presented and characteristics of the effects of electromagnetic radiation on the whole mammalian organisms are examined. Various reactions of the neuroendocrine system to electromagnetic radiation are described, with particular attention given to the adrenal system, and the combined effects of ionizing and microwave radiation in the flight environment are discussed. Results are also presented of a series of ...

1980-01-01

129

Spatial Variability of Reactive Mineral and Radionuclide Kd Distributions in the Tuff Confining Unit: Yucca Flat, Nevada Test Site

Full Text Available

2005-02-01

130

Mira variables - Pulsation, mass loss and evolution

Abstract not provided

2008-03-03

131

Asymptotic functions of many variables and singular operations with Schwartz distributions

Recent developments in the analysis of Mira atmosphere, the determination of the pulsation mode, the problem of mass loss, and the evolution of the Mira variables are covered. Model atmospheres for Mira variables, including the opacities of the molecules expected in very late M-type atmospheres are discussed. The pulsation constant for Omicron Ceti is evaluated using T(eff) = 2900 + or - 200 K, and it is concluded that Miras are fundamental mode pulsators. The importance of molecular opacity to the driving of mass loss is evaluated, and it is pointed out that the radiation pressure on molecules is not a major factor in driving mass loss from Mira. Mass loss is considered as a factor in the calculations of the periods for Mira variables. 30 refs.

1990-05-28

132

A Simulation Model for Estimating Airport Terminal Area ...

A theory of the asymptotic functions for the case of many variables is presented. It is shown that the class F(R"N) of these generalized functions is closed in respect to the linear algebraic and analytic operations, multiplication as well as a set of linear and polynomial changes of the variables. The existence in F(R"N) of analogues (consistent with the linear operations) of the Schwartz distributions with point support is proved. In terms of these analogues, some formulae for singular products and changes of variables of the Dirac #delta#-function and its derivatives #delta#"("i")(x), x is an element of R"N, are given. (author). 14 refs.

1992-10-19

133

Variable-speed hydro evolves

... AIR TRAFFIC, TERMINAL FLIGHT ... FLIGHT, RANDOM VARIABLES, STOCHASTIC PROCESSES ... COMPUTER PROGRAMS, QUEUEING THEORY. ...

1971-05-01

134

Tidal spin-up and magnetic braking in cataclysmic variables

Success in improving hydropower project efficiency has opened more global markets for variable-speed generator technology. Manufacturers continue to test the markets as the technology evolves. The potential of variable-speed application becomes evident considering that more than 150 pumped storage plants, with a combined capacity exceeding 100,000 MW, are in operation globally.

1993-10-01

135

Moderate deviations for stationary sequences of Hilbert valued bounded random variables

Based on proposed models for the tidal spin-up and magnetic braking of stars with a convective outer envelope, it is suggested that the rotation of secondaries in cataclysmic variables is not necessarily synchronized with the orbital revolution. This may provide an explanation for the observed large range in the mass transfer rate (at the same orbital period) of cataclysmic variables above the period gap. (author).

136

Long-run determinants of pollution: A robustness analysis

In this paper, we derive the moderate deviation principle for stationary sequences of bounded random variables with values in a Hilbert space. The conditions obtained are expressed in terms of martingale-type conditions. The main tools are martingale approximations and a new Hoeffding inequality for non adpated sequences of Hilbert-valued random variables. Applications to Cramer-Von Mises statistics, functions of linear processes and stable Markov chains are given.

2008-01-01

137

British Library Electronic Table of Contents (United Kingdom)

This paper examines how robust economic, political, and demographic variables are related to water and air pollution. Employing Bayesian Averaging of Classical Estimates (BACE) for a cross section of 47 countries, 34 variables and 3 proxies for air and water pollution over a period from 1980 to 2000 we confirm the environmental Kuznets curve hypothesis and highlight the relevance of variables that are not directly related to production.

2009-01-01

138

Joint distributions and tachyons

EUVE Observations of Nonmagnetic Cataclysmic Variables

In recent years there has been a renewed interest in the treatment of quantum mechanics in terms of joint distribution functions, i.e. functions of momentum and position coordinates p and q. The author considers j.d.f. in the sense of classical probability theory of a stochastic variable. The j.d.f. is then interpreted as the probability that the variables p and q have certain values, the variables being considered as a property possessed by the object system. This formalism is used to provide a unified description of bradyons and tachyons. (Auth.).

139

Circadian and circatrigintan respiratory and related intermodulations in the crab Barytelphusa guerini.

The authors summarize EUVE's contribution to the study of the boundary layer emission of high accretion-rate nonmagnetic cataclysmic variables, especially the dwarf novae SS Cyg, U Gem, VW Hyi, and OY Car in outburst. They discuss the optical and EUV light curves of dwarf nova outbursts, the quasi-coherent oscillations of the EUV flux of SS Cyg, the EUV spectra of dwarf novae, and the future of EUV observations of cataclysmic variables.

2001-09-05

140

BMFT. The 'biotechnology 2000' project. Annual report 1991. BMFT. Programm Biotechnologie 2000. Jahresbericht 1991

Respiration and related physiologic variables in different tissues of Barytelphusa guerini and the respiration of this freshwater crab as a whole are closely synchronized in phase and in frequency along the circadian scale, in the face of large differences in circadian amplitude. A very close timing of most of the 36 variables examined in 2 separate circadian profiles and a modulation of some of these variables in added profiles as a function of lunar stage are clearly demonstrable, statistically significant and illustrative of time relations at 2 interacting frequencies. PMID:6745009

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141

Yeast as a Model System to Study Tau Biology

The ''biotechnology 2000'' project is supervised by the project sponsor ''biology, energy, ecology'' at Forschungszentrum Juelich on behalf of the Federal Ministry for Research and Technology. The project activities cover the development of techniques and methods, cell biology, gene structure and gene regulation, photosynthetic production processes, biological hydrogen production, synthetic biology, protein design, neurobiological research, biosystems, plant breeding, phytomedicine and plant protection, the biology of waste disposal methods, research into methods which replace animal experiments, biological safety research, technology risk assessment, and ethical aspects. A general survey introduces the promoted projects, and standardized data sheets briefly introduce the individual ...

1992-01-01

142

Structure, reactivity, and biological properties of hidantoines; Estrutura, reatividade e propriedades biologicas de hidantoinas

Hyperphosphorylated and aggregated human protein tau constitutes a hallmark of a multitude of neurodegenerative diseases called tauopathies, exemplified by Alzheimer's disease. In spite of an enormous amount of research performed on tau biology, several crucial questions concerning the mechanisms of tau toxicity remain unanswered. In this paper we will highlight some of the processes involved in tau biology and pathology, focusing on tau phosphorylation and the interplay with oxidative stress. In addition, we will introduce the development of a human tau-expressing yeast model, and discuss some crucial results obtained in this model, highlighting its potential in the elucidation of cellular processes leading to tau toxicity.

2011-04-06

143

On vortices heating biological excitable media

Hydantoin (imidazolidine-2,4-dione) is a 2,4-diketotetrahydroimidazole discovered by Baeyer in 1861. Thiohydantoins and derivatives were prepared, having chemical properties similar to the corresponding carbonyl compounds. Some biological activities (antimicrobial, anticonvulsant, schistosomicidal) are attributed to the chemical reactivity and consequent affinity of hydantoinic rings towards biomacromolecules. Therefore, knowledge about the chemistry of hydantoins has increased enormously. In this review, we present important aspects such as reactivity of hydantoins, acidity of hydantoins, spectroscopy and crystallographic properties, and biological activities of hydantoin and its derivatives. (author)

2008-07-01

144

Confocal Imaging of Biological Tissues Using Second Harmonic Generation

An extension of the Hodgkin-Huxley mathematical model for the propagation of nerve signal which takes into account dynamical heat transfer in biological tissue is derived and fine tuned with existing experimental data. The medium is heated by Joule's effect associated with action potential propagation, leading to characteristic thermal patterns in association with spiral and scroll waves. The introduction of heat transfer-necessary on physical grounds-provides a novel way to directly observe the movement, regular or chaotic, of the tip of spiral waves in numerical simulations and possibly in experiments regarding different biological excitable media.

2009-11-30

145

Advances in molecular biology: impact on rotavirus vaccine development.

A confocal microscopy imaging system was devised to selectively detect Second harmonic signals generated by biological tissues. Several types of biological tissues were examined using this imaging system, including human teeth, bovine blood vessels, and chicken skin. All these tissues generated strong second harmonic signals. There is considerable evidence that the source of these signals in tissue is collagen. Collagen, the predominant component of most tissues, is known to have second order nonlinear susceptibility. This technique may have diagnostic usefulness in pathophysiological conditions characterized by changes in collagen structure including malignant transformation of nevi, progression of diabetic complications, and abnormalities in wound healing.

2000-03-06

146

Unearthing the Phylogenetic Roots of Sleep

The first candidate rotavirus vaccine was a live attenuated oral vaccine made by the classical empirical method of serial passage of virus in tissue culture cells. Current tetravalent vaccine candidates that are in the final stages of efficacy testing in the United States were made by genetic reassortment. This article briefly highlights how advances in the basic understanding of the molecular biology of rotaviruses have facilitated vaccine development. New approaches for second-generation vaccines and improvements in vaccine efficacy based on further exploitation of the tools and knowledge of rotavirus molecular biology and pathogenesis are discussed. PMID:8752289

1996-09-01

147

Towards a more functional concept of causality in cancer research

Why we sleep remains one of the enduring unanswered questions in biology. At its core, sleep can be defined behaviorally as a homeostatically regulated state of reduced movement and sensory...Full Text Available

2008-08-05

148

The biology of lichen communities in Livingston Island ... - NASA

Advances in molecular technologies challenge the different concepts of causality in biology, epidemiology and multistage mathematical models. The lack of integration of the different aspects of causality...Full Text Available

149

The biological aspects and behaviour of Heliothis virescens Fabricius adults from irradiated diapausal pupae

-Evaluacion de la fotosintesis y respiracion de especies de macroliquenes significativas en la tundra antartica. -Estudio de las isoenzimas en liquenes ...

150

The Structure of Plant Cell Walls

... bollworm fertility gamma radiation genetic radiation effects life span mating

1974-07-22

151

The Shifty Nature of Grains

The molecular structure, chemical properties, and biological function of the xyloglucan polysaccharide isolated from cell walls of suspension-cultured sycamore (Acer pseudoplatanus)...Full Text Available

1973-01-01

152

The International Reference Preparation of Erythropoietin*

... Astronomy & Space Biology Chemistry & Materials Computing Earth & Environment Education ... Materials Research Center at the University of Chicago, one of nearly 30 NSF-supported Materials ...

153

The European Bioinformatics Institute's data resources

The WHO Expert Committee on Biological Standardization authorized the National Institute for Medical Research to establish an International Reference Preparation of Erythropoietin on the basis of the...Full Text Available

1966-01-01

154

Studies of the action of hypoglycin-a, a hypoglycaemic substance

As the amount of biological data grows, so does the need for biologists to store and access this information in central repositories in a free and unambiguous manner. The European Bioinformatics Institute...Full Text Available

2003-01-01

155

Reporting Problems to FDA

Some biological effects of hypoglycin-A, a compound isolated from the fruit of Blighia sapida, have been investigated. Administration of this compound to animals caused drowsiness...Full Text Available

1958-06-01

156

Medline Plus

Enter Search terms A-Z Index Home Food Drugs Medical Devices Vaccines, Blood & Biologics Animal & Veterinary Cosmetics Radiation-Emitting Products Tobacco ...

157

Real-time neutron scattering investigations of biological signal transduction dynamics

Real-time neutron scattering investigations of biological signal transduction dynamics

During their catalytic cycle, proteins involved in biological signal transduction undergo unexpectedly large conformational changes, which are at the core of their biological functioning. Until now it has been extremely difficult to obtain experimental insight into the nature of these conformational changes. Mathematical modeling and time-resolved X-ray crystallography have resulted in probable routes along which these conformational changes may take place, but so far this fundamental biological phenomenon has hardly been tackled experimentally. Here, we report on an attempt to observe structural changes in Photoactive Yellow Protein with time-resolved small-angle neutron scattering using diffractometer D22 at the high-flux reactor of the Institut Laue-Langevin, Grenoble, France.

2005-07-01

158

Real Time Trajectory Planning for Groups of Unmanned ...

During their catalytic cycle, proteins involved in biological signal transduction undergo unexpectedly large conformational changes, which are at the core of their biological functioning. Until now it has been extremely difficult to obtain experimental insight into the nature of these conformational changes. Mathematical modeling and time-resolved X-ray crystallography have resulted in probable routes along which these conformational changes may take place, but so far this fundamental biological phenomenon has hardly been tackled experimentally. Here, we report on an attempt to observe structural changes in Photoactive Yellow Protein with time-resolved small-angle neutron scattering using diffractometer D22 at the high-flux reactor of the Institut Laue-Langevin, Grenoble, France

2005-04-11

159

... kinematic model for the robots and designed ... theoretic approach for modeling mobile robot teamn formations". ... "UUV teams, control from a biological ...

2005-08-22

160

R virgatipes

... fl.biology.usgs.gov/herps/Frogs_and_Toads/R_virgatipes/r_virgatipes.html Page Contact Information: SESC Webmaster Page ... ...

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161

R sphenocephala

... fl.biology.usgs.gov/herps/Frogs_and_Toads/R_sphenocephala/r_sphenocephala.html Page Contact Information: SESC Webmaster Page ... ...

162

R heckscheri

... fl.biology.usgs.gov/herps/Frogs_and_Toads/R_heckscheri/r_heckscheri.html Page Contact Information: SESC Webmaster Page ... ...

163

R grylio

... fl.biology.usgs.gov/herps/Frogs_and_Toads/R_grylio/r_grylio.html Page Contact Information: SESC Webmaster Page ... ...

164

R clamitans

... fl.biology.usgs.gov/herps/Frogs_and_Toads/R_clamitans/r_clamitans.html Page Contact Information: SESC Webmaster Page ... ...

165

R capito

Probiotic Bacteria as Biological Control Agents in Aquaculture

... fl.biology.usgs.gov/herps/Frogs_and_Toads/R_capito/r_capito.html Page Contact Information: SESC Webmaster Page ... ...

166

There is an urgent need in aquaculture to develop microbial control strategies, since disease outbreaks are recognized as important constraints to aquaculture production and trade and since the development...Full Text Available

2000-12-01

167

Orphan GPCR research

New Developments in the Use of Histamine and Histamine Receptors

Orphan G protein-coupled receptors (GPCRs) are receptors lacking endogenous ligands. Found by molecular biological analyses, they became the roots of reverse pharmacology, in which receptors are attempted...Full Text Available

2008-03-01

168

Neomusotima Fuscolinealis (Lepidoptera: Pryalidae) is an Unsuitable Biological Control Agent of Lygodium japonicum

Histamine and the histamine receptors are important regulators of a plethora of biological processes, including immediate hypersensitivity reactions and acid secretion in the stomach. In these...Full Text Available

2011-04-01

169

Molecular Aspects of Thyroid Hormone Actions

... la polilla fueron importadas a la facilidad de cuarentena en el Laboratorio de Control Biológico de Florida, ... ...

170

Microfluidic local perfusion chambers for the visualization and manipulation of synapses

Cellular actions of thyroid hormone may be initiated within the cell nucleus, at the plasma membrane, in cytoplasm, and at the mitochondrion. Thyroid hormone nuclear receptors (TRs) mediate the biological...Full Text Available

2010-04-01

171

Labelling methods for #alpha#-melanocyte stimulating hormone: an immunological and biological comparative study

SummaryThe polarized nature of neurons as well as the size and density of synapses complicates the manipulation and visualization of cell biological processes that control synaptic...Full Text Available

2010-04-15

172

How frugal is mother nature with haplotypes?

1981. p. 21. France Ghanem, G. Roland, MT Libert, A. Gossuin, A. Maerschalk,

1981-04-01

173

General Disclaimer One or more of the Following Statements may ...

Motivation: Inference of haplotypes from genotype data is crucial and challenging for many vitally important studies. The first, and most critical step, is the ascertainment of a biologically...Full Text Available

2009-01-01

174

Fixation of CO_2 and export of photosynthate by the carpel in Pisum sativum

Hie synthesis of diverse biologically important compounds, under condi- tions which existed on the earth in the initial period of its evolution, ha; ...

175

Evaluating Phylogenetic Congruence in the Post-Genomic Era

... School of Plant Biology. v. 23(2) p. 316-322. carbon dioxide absorption carbon

1970-01-01

176

Estimation of "1"3"7Cs body burden in Japanese, 2

Congruence is a broadly applied notion in evolutionary biology used to justify multigene phylogeny or phylogenomics, as well as in studies of coevolution, lateral gene transfer, and as evidence for...Full Text Available

2011-01-01

177

DNA synthesis inhibition in mammalian cells as a test for mutagenic carcinogens

The biological half-life of "1"3"7Cs in the total body of human subjects was determined in 23 individuals of Japanese male adult in their normal works by measuring amount of "1"3"7Cs in both their total body and daily urine in the same period. For the group, the value was determined by averaging the half-lives for individuals, by comparing the mean body burden and the mean daily urinary excretion, or by applying a curve fitting method to the body burden estimate. The biological half-life averaged 86 days, ranging from 50 to 161 days. The averages of the biological half-lives for the group were 83, 87 and 82 days in the different periods of observation. By the curve fitting method, 85 days was found for the group. The biological half-life for the individuals depended on both body weight and age, to a lesser extent, of the subjects. (author).

178

Computational biology for ageing

Current models of DNA repair of biological damage are reviewed correlating the similarity between carcinogenesis and mutagenesis theories. (PCS)

1979-01-01

179

Combining Satellite and in Situ Data with Models to Support Climate Data Records in Ocean Biology

High-throughput genomic and proteomic technologies have generated a wealth of publicly available data on ageing. Easy access to these data, and their computational analysis, is of great importance in...Full Text Available

2011-01-12

180

The satellite ocean color data record spans multiple decades and, like most long-term satellite

2011-01-01

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181

Clinical spectrum

Chemical and Biological Warfare: A Manageable Problem

A tunable diode laser is used to obtain infrared spectra of carbon dioxide in biological materials. The spectral resolution is sufficient to readily distinguish differing isotopic species. The technique may prove useful in clinical tests.

1987-11-01

182

CAAX-box protein, prenylation process and carcinogenesis

... On 20 March 1995, members from the religious cult Aum Shinrikyo released sarin and VX nerve gas into the Tokyo subway system. At the height of ...

2003-01-27

183

Breast cancer in the elderly.

CAAX proteins are widely involved in global cellular functions such as proliferation, differentiation, and carcinogenesis. As an important modulator of biological activity, signal transduction via protein...Full Text Available

184

Bioterrorism and Biocrimes: The Illicit Use of Biological Agents ...

Breast cancer in the elderly has attracted considerable interest in recent years for three main reasons. Firstly, information concerning the profile (clinical and biological) of the disease in the geriatric...Full Text Available

1995-11-01

185

Biology of lichen communities in Antarctica. - NASA

... view on the utility of such attacks, see JH Rothschild, Tomorrow's Weapons ... Aum Shinrikyo may have had a stolen vaccine anthrax strain incapable ...

2001-02-01

186

Biology of Pseudomonas stutzeri

-Estudio sobre la fijacion de nitrogeno, fotosintesis y reconolizacion ... - Fotosintesis y relaciones hidricas en liquenes nanofruticulosos antarticos. ...

187

Biological effects of Maytenus ilicifolia extract on the survival of Escherichia coli AB1157 and BH110 strains

Pseudomonas stutzeri is a nonfluorescent denitrifying bacterium widely distributed in the environment, and it has also been isolated as an opportunistic pathogen from humans. Over the...Full Text Available

2006-06-01

188

Biological Studies of Bagous Hydrillae

English 2004 [2 p.] Brazil Soares, SF Dire, Glaucio Abreu, Paulo Jesus,

2004-08-25

189

Analysis of Fisheries and Aquaculture

... Ceratophyllaceas Ceratophyllum doemesm 96 4 3 4 107 Convulivulacme Ipomea aquatica 13 13 Haloragaceae Myriophyflum trahycatpum 15 15 ...

1994-09-01

190

An Artificial Immune System-Inspired Multiobjective ...

... abundance though an effect on escapement. The lobster aquaculture model continues to be updated as new biological ... become available. A monograph on the economics of aquaculture is near completion....

191

Allozyme Divergence in Two Syntopic Liolaemus of the Liolaemus monticola Group (Squamata: Tropiduridae)

... BFS Breadth-First Search BIS Biological Immune System CCNA Cisco-Certified Network Associate CDIS Computer Defense Immune System ...

2007-03-01

192

A unified framework for biological evolution and stochastic quantization

... shareware for population genetic analysis. Molecular Biology and Biotecnology Centre, Univ. of Alberta, Canada. enlarge figure Fig. ... ...

193

A framework for evolutionary systems biology

We investigate the profound relation between the equations of biological evolution and quantum mechanics by writing a biologically inspired equation for the stochastic dynamics of an ensemble of particles. Interesting behavior is observed which is related to a new type of stochastic quantization. We find that the probability distribution of the ensemble of particles can be decomposed into eigenfunctions associated to a discrete spectrum of eigenvalues. In absence of interactions between the particles, the out-of-equilibrium dynamics asymptotically relaxes towards the fundamental state. This phenomenon can be related with the Fisher theorem in biology. On the contrary, in presence of scattering processes the evolution reaches a steady state in which the distribution of the ensemble of particles is characterized by a Bose-Einstein statistics. In order to show a concrete example of this stochastic quantization we have solved ...

2010-01-01

194

The implications of tolerance system interpretation on past and present dimensional variability studies

BackgroundMany difficult problems in evolutionary genomics are related to mutations that have weak effects on fitness, as the consequences of mutations with large effects are often...Full Text Available

195

Man-made disasters: A cross-national analysis

Dimensional variability studies and published dimensional variability standards have been used by the foundry industry for years as an indicator of the casting process` ability to produce uniform parts. These studies are an extremely useful tool in the continuous ``dimensional dialogue`` between foundries and customers. The nature of these studies, and of the current tolerancing systems used by casting designers, leaves room for some misinterpretation and misuse of these study results. This paper contains two important discussions. The first part explains exactly what these studies represent. Following this is a brief explanation on dimensional and geometric tolerances and how they communicate dimensional requirements.

1994-12-31

196

British Library Electronic Table of Contents (United Kingdom)

This research investigates the impact of national culture and several institutional factors on the safety performance of society and establishes statistically significant relationships between those variables. As expected, the research results reveal that some cultural variables such as uncertainty avoidance, gender orientation and institutional variables such as the degree of law avoidance can directly influence the safety performance of the society. The findings also support the inverted u-curve (Safety Kuznet curve) hypothesis indicating even if we expect a negative trend at the beginning stage of industrialization, we can expect a positive trend in safety performance as their income level continues to improve beyond a certain point.

2011-01-01

197

Go vs. no-go - potential and limitations of continuous-variable quantum computing by measurements

Creep properties of modified 9 Cr-1 Mo steel

In this talk, we explore the feasibility of quantum computation using continuous-variable systems by means of local measurements only. In the first part of the talk, we will identify crucial limitations that arise when starting from Gaussian cluster states. This is done by resorting to a Gaussian projected entangled pair picture as well as to notions of continuous-variable quantum repeater networks. In the second part, we look at instances in which these limitations can be overcome, and how suitable encodings of qubits in oscillators and feasible non-Gaussian resource states give rise to universal schemes for quantum computing.

2010-07-01

198

Vascular Effects of Photodynamic and Pulsed Dye Laser Therapy Protocols

Creep properties of modified 9 Cr-1 Mo steel, an alloy significantly improved in elevated-temperature strength over 2 1/4 Cr-1 Mo and other similar alloys, are presented here. Data are primarily on material in the normalized and tempered condition. Effects of variables such as isothermal annealing treatment, cold work, normalizing temperature, tempering temperature, notch, and biaxial stress state have also been examined. Data analysis and comparisons have shown that modified 9 Cr-1 Mo alloy is very insensitive in response to several material variables, heat treatments, and specimen design variables.

1983-01-01

199

Variability in Melanoma Metalloproteinase Expression Profiling

Background and ObjectivePulsed dye laser (PDL) treatment of cutaneous vascular lesions is associated with variable and unpredictable efficacy. Thus, alternative treatment...Full Text Available

2008-11-01

200

The role of fatigue variability in life prediction of an #alpha#+#beta# titanium alloy

The proteolytic activities of a disintegrin and metalloproteinase (ADAM); a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS), and matrix metalloproteinase (MMP) families play important...Full Text Available

2010-12-01

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201

Spatial and Temporal Variability of Column Integrated Aerosol - NASA

The fatigue life variability of the #alpha#+#beta# titanium alloy, Ti-6Al-2Sn-4Zr-6Mo increased with decreasing stress level. The variability in life was found to be due to segregation of lives due to two failure mechanisms. A bimodal cumulative distribution model was shown to accurately describe the combined failure modes. The nominal failure processes for the two regimes were similar, with crack nucleation occurring in equiaxed #alpha#p particles, irrespective of life or stress level. However the variability in life was not controlled by the size of the crack-nucleating #alpha#p, but rather by the ability of the material to distribute deformation and avoid early crack nucleation.

2004-06-10

202

Spatial Variability of Wave Data from Todos Santos Bay, Baja California, Mexico

the southern Arabian Gulf region left its signature on the heterogeneous aerosol .... Arabian Gulf region, since large differences in ? may be caused by ...

203

Organismos que causan enfermedades transmitidas por los alimentos ...

... and operation of marine structures and to estimate coastal sediment transport. While the timely collection and report of high ... ...

204

Order in Spontaneous Behavior

... Variable, Alimentos mal enlatados, especialmente verduras enlatadas en el hogar; pescado fermentado, papas asadas en papel de aluminio, ajo envasado. ...

205

Optimization of extraction of high-ester pectin from passion fruit peel (Passiflora edulis flavicarpa) with citric acid by using response surface methodology

Brains are usually described as input/output systems: they transform sensory input into motor output. However, the motor output of brains (behavior) is notoriously variable, even under identical sensory...Full Text Available

206

British Library Electronic Table of Contents (United Kingdom)

A central composite design was employed to optimize the extraction of pectin with citric acid. The independent variables were citric acid concentration (0.086-2.91% w/v) and extraction time (17-102min). The combined effect of these variables on the degree of esterification was investigated. Results have shown that the generated regression models adequately explained the data variation and significantly represented the actual relationship between the independent variables and the responses. Besides that, the citric acid concentration was the most important factor to affect the degree of esterification, as it exerted a significant influence on the dependent variable. Lower citric acid concentration increased the pectin degree of esterification. The surface response showed the relationships b...

2008-01-01

207

Multifractal Analysis of Multiple Ergodic Averages

Modeling hydrologic responses to deforestation/forestation and ...

In this paper we present a complete solution to the problem of multifractal analysis of multiple ergodic averages in the case of symbolic dynamics for functions of two variables depending on the first coordinate.

2011-01-01

208

Koji Mukai's Bibliography - Astrophysics Science Division Staff ...

Worldwide century-long forest hydrologic research has documented that deforestation and forestation (i.e. reforestation and afforestation) can have variable ...

209

Fractal dynamics in physiology: Alterations with disease and aging

Jul 25, 2011 ... Koji Mukai's Bibliography. Invited Reviews. Mukai, K. 1994, "ASCA PV Phase Observations of Cataclysmic Variables," in "New Horizon of X-ray ...

210

Floral ontogeny of Annonaceae: evidence for high variability in floral form

According to classical concepts of physiologic control, healthy systems are self-regulated to reduce variability and maintain physiologic constancy. Contrary to the predictions of homeostasis, however,...Full Text Available

2002-02-19

211

Enhancement of bioleaching of a spent Ni/Mo hydroprocessing catalyst by Penicillium simplicissimum

Background and AimsAnnonaceae are one of the largest families of Magnoliales. This study investigates the comparative floral development of 15 species to understand the basis for...Full Text Available

2010-10-01

212

British Library Electronic Table of Contents (United Kingdom)

Statistically based experimental designs were applied to screen and optimize the bioleaching of spent hydrocracking catalyst by Penicillium simplicissimum. Eleven factors were examined for their significance on bioleaching using a Plackett-Burman factorial design. Four significant variables (pulp density, sucrose, NaNO"3, and yeast extract concentrations) were selected for the optimization studies. The combined effect of these variables on metal bioleaching was studied using a central composite design (CCD). Second-order polynomials were established to identify the relationship between the recovery percent of the metals and the four significant variables. The optimal values of the variables for maximum metals bioleaching were as follows: pulp density (4.0%, w/v), sucrose (90g/L), NaNO"3 (2...

2011-01-01

213

Effects of wildfires on environmental variability: a comparative analysis using different spectral indices, patch metrics and thematic resolutions

British Library Electronic Table of Contents (United Kingdom)

Knowledge on environmental variability and how it is affected by disturbances is crucial for understanding patterns of biodiversity and determining adequate conservation strategies. The aim of this study is to assess environmental variability in patches undergoing post-fire vegetation recovery, identifying trends of change and their relevant drivers. We particularly evaluate: the value of three spectral indices derived from Landsat satellite data [Normalized Burn Ratio (NBR), Normalized Difference Vegetation Index (NDVI) and Wetness Component of the Tasseled Cap Transformation (TCW)] for describing secondary succession; the effectiveness of three metrics (diversity, evenness and richness) as indicators of patch variability; and how thematic resolution can affect the perception of environme...

2010-01-01

214

Effects of Climatic Variability and Land Use on American Drylands...

ENSO affects sex ratio progeny in captive Iberian red deer despite a steady feeding regime

Wildlife Refuge, CA Rare and endangered endemic plants Diana Anderson Northern Arizona University Geomorphology Kathryn Thomas USGS, Flagstaff, AZ Vegetation dynamics John...

2011-09-30

215

British Library Electronic Table of Contents (United Kingdom)

Climate variability greatly affects animals through direct and indirect effects. Animals with slow reproductive adaptation to ecological changes such as large mammals are likely to have evolved mechanisms to anticipate early such impacts of climate variability on the environment. One of the adaptive mechanisms between reproductive costs and benefits in mammals affects parental investment through biases in sex ratio. Deer might be likely to show an early detection of climate variability because conception takes place in early autumn, but the main raising cost in deer concerns lactation, which takes place at the end of the following spring. The aim of this paper is to assess whether there is a relationship between global indices of climate variability such as El Ni?o-Southern Oscillation (EN...

2011-01-01

216

DESIGN STUDY OF CONTINUOUSLY VARIABLE ROLLER CONE - NASA Technical ...

Comparing Genomes within the Species Mycobacterium tuberculosis

pedel preo,ure. (_PD). VSO may be developed by nor_:el epeed-o-_eter means at the output. ,haft or it may be derived ...

217

Climate change/variability implications on hydroelectricity generation in the Zambezi River Basin

The study of genetic variability within natural populations of pathogens may provide insight into their evolution and pathogenesis. We used a Mycobacterium tuberculosis high-density...Full Text Available

2001-04-01

218

British Library Electronic Table of Contents (United Kingdom)

The study has analysed the effects of various factors on hydroelectric power generation potential to include climate change/variability, water demand, and installation of proposed hydroelectric power schemes in the Zambezi River Basin. An assessment of historical (1970?2000) power potential in relation to climate change/variability at existing hydro electric power schemes(Cahora Bassa, Kariba, Kafue Gorge and Itezhi-Tezhi) in the Zambezi River Basin was conducted. The correlation of hydroelectric power potential with climate change/variability aimed at observing the link and extent of influence of the latter on the former was investigated. In order to predict the future outlook of hydro electric power potential, General Circulation Models (GCM) were used to generate projected precipitation...

2011-01-01

219

Characterizing partial upwellings ... - Lake Tahoe Validation - NASA

Baxter Q-operator and Separation of Variables for the open SL(2,R) spin chain

measure meteorological variables and bulk water temper- ature. The locations of the buoys are given in Table 1. TB2 and TB3 were moved slightly farther south ...

220

Adaptive Pareto Set Estimation for Stochastic Mixed Variable ...

We construct the Baxter Q-operator and the representation of the Separated Variables (SoV) for the homogeneous open SL(2,R) spin chain. Applying the diagrammatical approach, we calculate Sklyanin's integration measure in the separated variables and obtain the solution to the spectral problem for the model in terms of the eigenvalues of the Q-operator. We show that the transition kernel to the SoV representation is factorized into the product of certain operators each depending on a single separated variable. As a consequence, it has a universal pyramid-like form that has been already observed for various quantum integrable models such as periodic Toda chain, closed SL(2,R) and SL(2,C) spin chains.

2003-01-01

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221

A novel approach to the dynamics of Szekeres dust models

... Direct Search (SMOMADS) and Paciencia's NMADS [45] based on Kim and de Weck's ... Todd Paciencia for his foundational contributions. ...

2009-03-01

222

[The indicators of biological age and accelerated aging in liquidators of the consequences of radiation emergency].

We obtain an elegant and useful description of the dynamics of Szekeres dust models (in their full generality) by means of "quasi--local" scalar variables constructed by suitable integral distributions that can be interpreted as weighed proper volume averages of the local covariant scalars. In terms of these variables, the field equations and basic physical and geometric quantities are formally identical to their corresponding expressions in the spherically symmetric LTB dust models. Since we can map every Szekeres model to a unique LTB model, rigorous results valid for the latter models can be readily generalized to a non--spherical Szekeres geometry. The new variables lead naturally to an initial value formulation in which all scalars are expressed as scaling laws in terms of their values at an arbitrary initial space slice. These variables also yield a significant simplification of numerical work, ...

2011-01-01

223

Tumorigenic and tumoricidal actions of ionizing radiations

The biological age (BA) of the majority of the liquidators of the consequences of the radiation accidents in the Navy and of the liquidators of the Chernobyl' APS accident exceeds the medium standard and the DBA (due BA). The index of the BA can be a characteristic of the influence of the social-hygienic factors on the health condition of the Special Risk Subunit--the liquidators of the consequences of the radiation accidents. It was established, that the radiation influence concerns to the factors dramatically increasing the BA and the rate of senescence of the liquidators of the consequences of the radiation accidents. PMID:21809627

2011-01-01

224

Topological modeling of the reactive capacity and biological activity of some amino-polysaccharides

The book is divided into two approximately equal parts. The first four chapters are relatively lengthy and cover the basic principles of radiation biology, carcinogenesis and therapy, along with a brief introduction to radiological physics to orient the reader without background in this specialized related discipline. The remainder consists of twenty-four relatively brief chapters, each covering the radiation biology of a specific organ, tissue, or systems tissues, with emphasis on the tumorigenic and tumoricidal action of ionizing radiations.

1983-01-01

225

British Library Electronic Table of Contents (United Kingdom)

The work is devoted to a microscopic analysis of the reactive capacity of chitin. An algorithm for modeling the deacetylation reaction in a monomeric unit of chitin is described. The reaction coordinate and the potential energy surface topography are determined taking into account the electron-vibrational interaction and low-symmetry perturbations within Jahn-Teller theory. Based on this algorithm, the topological modeling of the deacetylation process is performed for the first time and a mechanism of the biological activity of chitosan is proposed.

2011-01-01

226

The Fenton oxidation mechanism: reactivities of biologically relevant substrates with two oxidizing intermediates differ from those predicted for the hydroxyl radical.

Radionuclide X-ray fluorescence analysis of components of the environment

The application of kinetic probes that allow one to determine relative reactivities of biologically relevant substrates with oxidizing intermediates in the Fenton reagent (H2O2 plus Fe2+ in acidic aqueous...Full Text Available

1994-07-05

227

On new methods for standardization of samples in activation analysis of biological materials

The physical foundations and methodology are described of radionuclide X-ray fluorescence analysis. The sources are listed of air, water and soil pollution, and the transfer of impurities into biological materials is described. A detailed description is presented of the sampling of air, soil and biological materials and their preparation for analysis. Greatest attention is devoted to radionuclide X-ray fluorescence analysis of the components of the environment. (ES).

1983-01-01

228

New humic plant growth stimulant based on the neogene brown coals of Belarus

New standardization techniques of samples in multielement instrumental neutron-activation analysis (INAA) of biological materials (BM) are considered. New methodical developments of sample preparation techniques, BM tableting, creation of comparison standards and standardization of packing material are suggested. Correlated data on concentration of different elements in standard specimens-comparison standards are presented for mass INAA, that is: for phenol-formaldehyde resin-base and human blood-base synthetic standards. 7 refs.; 3 tabs.

1988-06-26

229

British Library Electronic Table of Contents (United Kingdom)

Data on a technology for the manufacture of a new biologically active humic preparation based on the Neogene brown coals deposited in Belarus are presented. The physicochemical properties of the preparation are given, and its biological activity is evaluated; the results of plant cultivation tests in the basic crops of the region?potatoes and grain crops?are also considered.

2011-01-01

230

Ion-Track Membranes and Their Use in Biological and Medical Applications

Generalized genetic code. A note on order-isomorphism/order-equivalence relations

This report is a brief review of biological and medical applications of ion-track membranes. The review aims at informing nuclear physicists about alternative (i.e. non-fundamental-science) use of heavy ion accelerators such as production of micro- and nano-porous materials. The ion-track membranes produced this way are employed in life sciences and numerous technological applications. The author focuses on recent results from the Flerov laboratory in co-operation with other scientific institutions and industrial partners.

2007-05-22

231

Determination of lead in biological and environmental samples by "2"0"3Pb isotope dilution substoichiometric method

Constructive and combinatorial relationships between order-isomorphisms and order-equivalence classes within the generalized genetic code are presented, not only for the biologically relevant groups of order 4, but also for finite groups of arbitrary order. The main result is the derivation of the number (and types) or order-equivalence classes for a group of order n. Finally, an extension of this work to all biologically admissible alternative codes is discussed.

1982-01-01

232

CRC handbook of biological effects of electromagnetic fields

A procedure for the determination of lead in various biological and environmental samples by "2"0"3Pb radioisotope dilution substoichiometric method is presented. The accuracy of the method by comparison with the literature values of reference materials appears to be good. The standard deviation of the method is less than 10%, and detection limit is about 0.1 #mu#g of lead. (author) 5 refs.

233

Biological solubilization of coal in aqueous and nonaqueous media

This book presents the current knowledge about the effects of electromagnetic fields on living matter. The three-part format covers dielectric permittivity and electrical conductivity of biological materials; effects of direct current and low frequency fields; and effects of radio frequency (including microwave) fields. The parts are designed to be consulted independently or in sequence, depending upon the needs of the reader. Useful appendixes on measurement units and safety standards are also included.

1986-01-01

234

Biological effects from electric fields associated with high voltage transmission lines

Current investigations into the biological solubilization of coal with microorganisms focus on the production of solubilizing activity in fungi. Test organisms for this work include a species of the yeast Candida previously isolated from a lignite outcrop, and P. chrysosporium, a filamentous higher fungus which has played a major role in lignin biodegradation research. The studies described are primarily exploratory in nature, and are fundamental to the design of more sophisticated inquiries into the physiology of fungal coal solubilization.

1987-01-01

235

Biological and Chemical Security

Efforts during the past year by the US Department of Energy and the Electric Power Research Institute-funded laboratories to investigate the biological effects from electric fields are described in resume form. Investigations generally have been summarized with objectives, accomplishments of the past year, and some indication of projected studies.

1983-11-01

236

7. Overview of radionuclide X-ray fluorescence analysis of components of the environment

The LLNL Chemical & Biological National Security Program (CBNP) provides science, technology and integrated systems for chemical and biological security. Our approach is to develop and field advanced strategies that dramatically improve the nation's capabilities to prevent, prepare for, detect, and respond to terrorist use of chemical or biological weapons. Recent events show the importance of civilian defense against terrorism. The 1995 nerve gas attack in Tokyo's subway served to catalyze and focus the early LLNL program on civilian counter terrorism. In the same year, LLNL began CBNP using Laboratory-Directed R&D investments and a focus on biodetection. The Nunn-Lugar-Domenici Defense Against Weapons of Mass Destruction Act, passed in 1996, initiated a number of U.S. nonproliferation and counter-terrorism programs including the DOE (now NNSA) Chemical and Biological ...

2002-12-19

237

2004 Reversible Associations in Structure & Molecular Biology

A survey is presented of studies dealing with radionuclide X-ray fluorescence analysis (RXFA) of impurities in the air, water, soil, sediments and biological materials, mainly blood, urine, hair, soft tissues and bones. Tabulated are lists of published works on RXFA of the air, water and biological materials. (ES).

1983-12-01

238

The peak to background method in quantitative ion microprobe analysis of thick biological specimens

The Gordon Research Conference (GRC) on 2004 Gordon Research Conference on Reversible Associations in Structure & Molecular Biology was held at Four Points Sheraton, CA, 1/25-30/2004. The Conference was well attended with 82 participants (attendees list attached). The attendees represented the spectrum of endeavor in this field coming from academia, industry, and government laboratories, both U.S. and foreign scientists, senior researchers, young investigators, and students.

2005-03-23

239

Chromium and manganese levels in biological samples of normal and night blindness children of age groups (3-7) and (8-12) years.

The use of the ratio of the characteristic intensity to the continuum background intensity (P/B ratio) of the X-ray spectrum for a quantitative ion microprobe (IMP) or PIXE (particle induced X-ray emission) analysis of thin biological specimens was proposed previously. The IMP analysis of thick biological specimens is also of considerable practical use. In this paper, the possibility of using the P/B ratio to quantify minor elements in thick biological specimens is investigated. The epoxy resin based standards with gradual concentrations of KCNS up to 0.6 mol/kg and NBS bovine liver were analyzed by a 27 MeV {alpha} particle microprobe. The measured peak to background ratios (between 4.4 to 5.7 keV) agreed well with the theoretical calculations. The calculations showed that the concentration dependence of the P/B ratios was determined mainly by the absorption of X-rays in specimens. The results indicate that the P/B method ...

1991-05-01

240

Biological in situ remediation of a former pond for trickling waste water containing explosives

This study was designed to compare the levels of chromium (Cr) and manganese (Mn) in scalp hair, blood, and urine of night blindness in children age ranged (3-7) and (8-12) years of both genders, comparing them to sex- and age-matched controls. A microwave-assisted wet acid digestion procedure, was developed as a sample pretreatment, for the determination of Cr and Mn in biological samples of night blindness children. The proposed method was validated by using conventional wet digestion and certified reference samples of hair, blood and urine. The digests of all biological samples were analyzed for Cr and Mn by electrothermal atomic absorption spectrometry. The results indicated significantly higher levels of Cr, whilst low level of Mn in the biological samples (blood and scalp hair) of male and female night blindness children, compared with control subjects of both genders. These data present guidance to clinicians and ...

2010-09-21

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241

Biological effects of radiowaves and microwaves

WASAG DECON developed a concept for the biological in situ remediation of an TNT-contaminated former seepage pond. This pond is located on the site of an ammunition factory in Lower Saxony. Unit 1982 all the waste water from the production buildings was directed into this pond, including TNT-contaminated water from the flushing of shells. Due to this practice, the sediment of the pond, the underlying soil and the groundwater became contaminated with TNT. The area of the soil contamination adds to abut 2.000 m{sup 2}. The remediation concept includes three steps: 1. Excavation of the most highly contaminated soil with TNT-concentrations above 1000 mg/kg. 2. Reduction of the remaining contamination by a biological in situ treatment using organic and inorganic amendments and mechanical tillage. After about to years of treatment, remediation goals of 50 mg/kg are expected to be reached on most of the area. 3. Contaminations eventually remaining in ...

2003-07-01

242

Variable Frequency Microwave Synthesis of Silver Nanoparticles

Heat production in biological materials due to absorption of radiowaves and microwaves can be used in applications as diverse as cancer treatment and cooking. However, the hazards of overexposure range from hyperthermia to cataracts and internal burns. To maximize the clinical benefits and minimize potential hazards, the biological effects of radiowaves and microwaves must be understood. Dielectric measurements can be used to determine the extent of such effects in various applications and at various levels of exposure. The values of maximum permissible exposure levels that are likely to be recommended aeat production in biological materials due to absorption of radiowaves and microwaves can be used in applications as diverse as cancer treatment and cooking. However, the hazards of overexposure range from hyperthermia to cataracts and internal burns. To maximize the clinical benefits and minimize potential hazards, the ...

1980-01-01

243

One-dimensional numerical simulation of free-electron laser (FEL) amplifier with incorporate variable-parameter wiggler magnets

Synthesis of silver nanoparticles based on a polyol process and variable frequency microwave (VFM) was investigated. Comparing to a thermal method, the reaction by VFM radiation was much faster. The effects of silver nitrate concentration, poly(N-vinylpyrrolidone) (PVP) concentration, reaction time and reaction temperature were studied. It was found that the higher concentration of silver nitrate, longer reaction time and higher temperature increased the particle size while the higher concentration of PVP decreased the particle size.

2006-02-15

244

Flow control with variable inflow as an alternative to conventional nozzle group control - automatic control of large capacity steam turbines

A physical model of free-electron laser (FEL) amplifier with variable-parameter wiggler magnets for one-dimensional numerical simulation is presented and a numerical example is given. The wiggler parameters, efficiency of energy conversion between electron beam and laser field, laser intensity, phase-space distributions and energy spectrum of electrons are computed. The period of synchronous oscillation and saturation value of laser intensity agree with estimated one.

245

Conference on climate and water. Volume 2

In the case of large capacity steam turbines the conventional nozzle group control is, for mechanical and thermodynamic reasons, diminishing more and more in importance in favour of variable pressure control. A design for constant-pressure operation as an alternative to nozzle group control is described; this demonstrates a series of important advantages compared with the latter. (orig.).

246

Conference on climate and water

This book contains the Proceedings of the Conference on Climate and Water under the following groupings: Impacts of climatic variability and change-resulting from the changes in hydrological variables; Aquatic environment; Terrestrial environment; Coastal zones and navigation; Urban and industrial water supply and drainage; Energy production; Intropogenic changes of climate and water management problems; Flood potential; Irrigation and land drainage.

1989-12-31

247

Variable-speed generation enhances hydro operation

This book contains the Proceedings of the Conference on Climate and Water under the following groupings: Impacts of climatic variability and change-resulting from the changes in hydrological variables; Aquatic environment; Terrestrial environment; Coastal zones and navigation; Urban and industrial water supply and drainage; Energy production; Intropogenic changes of climate and water management problems; Flood potential; Irrigation and land drainage.

1989-01-01

248

Intrapartum FHR monitoring and neonatal CT brain scan

Two major developments have given impetus to wider adoption of variable-speed turbine/generators in hydroelectric plants, both essentially environmental: (1) the need for stream-bed stability below river dams, and (2) the need to minimize fish damage. Also, the need to stabilize pumped-storage and generating efficiencies to match extreme changes in head levels has been a driving force. Variable-speed operation in hydro applications is relatively new to North America. In other parts of the world, it has been used in pumped-storage plants since 1971. In the US, and increasing potential exists for variable-speed hydro, considering the 30 pumped-storage plants already in operation and several river plants struggling with high head fluctuations--including four at stations operated by the Bonneville Power Administration. Several modifications to hydro-plant hardware and operating procedures are actively being considered at ...

1993-07-01

249

Intrapartum FHR monitoring and neonatal CT brain scan

The effect of fetal distress on the neonatal brain was investigated by neonatal CT brain scan, FHR monitoring and mode of delivery. This study involved 11 cases of full term vertex delivery in which FHR was recorded by fetal direct ECG during the second stage labor. All infants weighed 2,500 g or more. FHR monitoring was evaluated by Hon's classification. Neonatal brain edema was evaluated by cranial CT histgraphic analysis (Nakada's method). 1) Subdural hemorrhage was noted in 6 of 7 infants delivered by vacuum extraction or fundal pressure (Kristeller's method). 2) Intracranial hemorrhage was demonstrated in all of 3 infants with 5-min. Apgar score 7 or less. 3) Two cases with prolonged bradycardia and no variability had intraventricular or intracerebral hemorrhage which resulted in severe central nervous system damage. 4) The degree of neonatal brain edema correlated with 5-min. Apgar score. 5) One case with prolonged bradycardia and ...

1982-12-01

250

eDNA: A Bio-Inspired Reconfigurable Hardware Cell Architecture Supporting Self-organisation and Self-healing

The effect of fetal distress on the neonatal brain was investigated by neonatal CT brain scan, FHR monitoring and mode of delivery. This study involved 11 cases of full term vertex delivery in which FHR was recorded by fetal direct ECG during the second stage labor. All infants weighed 2,500 g or more. FHR monitoring was evaluated by Hon's classification. Neonatal brain edema was evaluated by cranial CT histgraphic analysis (Nakada's method). 1) Subdural hemorrhage was noted in 6 of 7 infants delivered by vacuum extraction or fundal pressure (Kristeller's method). 2) Intracranial hemorrhage was demonstrated in all of 3 infants with 5-min. Apgar score 7 or less. 3) Two cases with prolonged bradycardia and no variability had intraventricular or intracerebral hemorrhage which resulted in severe central nervous system damage. 4) The degree of neonatal brain edema correlated with 5-min. Apgar score. 5) One case with prolonged bradycardia and no ...

1982-01-01

251

Use of a trap garden to find additional genetically distinct isolates of the rust fungus Phragmidium violaceum to enhance biological control of European blackberry in Australia

This paper presents the concept of a biological inspired reconfigurable hardware cell architecture which supports self-organisation and self-healing. Two fundamental processes in biology, namely fertilization-to-birth and cell self-healing have inspired the development of this cell architecture. In biology as well as in our hardware cell architecture it is the DNA which enables these processes. We propose a platform based on the electronic DNA (eDNA) and show through simulation, its capabilities as a new generation of robust reconfigurable hardware platforms. We have created a Java based simulator to simulate our self-organisation and self-healing algorithms and the results obtained from this looks promising.

2009-01-01

252

British Library Electronic Table of Contents (United Kingdom)

Biological control agents can be more effective if their populations are genetically diverse, particularly when the target invasive plant comprises a range of genotypes with different susceptibilities and occurs across various microclimates. We report on the use of an efficient approach to find, in the native range, diverse isolates of a rust fungus for biological control. An outdoor trap garden containing various clones of invasive European blackberry (Rubus fruticosus agg.) collected in Australia, each with a different DNA phenotype, was established in France. Within 4?weeks of establishment, the leaf-rust fungus Phragmidium violaceum was recovered from all clones in the garden. Molecular analyses of eight recovered and purified isolates of the fungus from the garden revealed that they w...

2011-01-01

253

Pilot project ''measurement of efficacy'' - biological monitoring of antimony pollution in the Munich test area using a standardized grass culture

Pharmaceutical applications of cyclodextrins: effects on drug permeation through biological membranes

This pilot project was carried out for the purpose of testing methods for active biological monitoring. It covered a period of three years (until September 1994), including two years of exposure. The measurements served to determine pollutant levels in plants used as animal fodder and dust-borne heavy metal concentrations in different sites and, on this basis, to obtain indirect information on human exposure. Among others, the pilot project investigated the suitability of Italian rye-grass as a biological indicator for aluminium, arsenic, cadmium, cobalt, chromium, copper, iron, mercury, magnesium, manganese, nickel, lead, platinum, antimony, titanium, and zinc. (orig./GL).

254

British Library Electronic Table of Contents (United Kingdom)

Abstract Objectives- Cyclodextrins are useful solubilizing excipients that have gained currency in the formulator's armamentarium based on their ability to temporarily camouflage undesirable physicochemical properties. In this context cyclodextrins can increase oral bioavailability, stabilize compounds to chemical and enzymatic degradation and can affect permeability through biological membranes under certain circumstances. This latter property is examined herein as a function of the published literature as well as work completed in our laboratories. Key findings- Cyclodextrins can increase the uptake of drugs through biological barriers if the limiting barrier component is the unstirred water layer (UWL) that exists between the membrane and bulk water. This means that cyclodextrins are mo...

2011-01-01

255

On the selection and validation of biological treatment processes. The GDF experience; Le choix et la validation des procedes de traitement biologique. L`experience de GDF

Molecular biology of the renin-angiotensin system

The biological treatment process was selected by Gaz de France (GDF), the French national gas utility, for the de-pollution of an old gas works where the main pollutants are coal tars containing polycyclic aromatic hydrocarbons. Microorganism-based biological treatment techniques may involve bio-reactors, static ground knolls (where oxygen is brought through drains) and dynamic knolls (where oxygenation is carried out by turning up the soil). Issues on sampling, sorting, process testing, site preparation, process control, etc. are reviewed

1996-12-31

256

MGV: a generic graph viewer for comparative omics data

This paper reviews the molecular biology of the renin-angiotensin system. The renin gene structure is analyzed in detail, including an examination of the putative regulatory regions. The combined action of these regulatory sequences would result in the complex, tissue-specific expression and regulation observed in vivo. The expression of the tissue renin-angiotensin systems, which may have important physiological functions, is also described. In addition, the pathway of renin biosynthesis and secretion is reviewed. This includes speculation on the fate of circulating prorenin and the physiological role of multiple renin forms and secretory pathways. The molecular approaches described in this paper have greatly advanced our knowledge of the biology of the renin-angiotensin system. Future studies using these and other approaches should provide further insight into this complex system.

1988-10-01

257

British Library Electronic Table of Contents (United Kingdom)

Motivation: High-throughput transcriptomics, proteomics and metabolomics methods have revolutionized our knowledge of biological systems. To gain knowledge from comparative omics studies, strong data integration and visualization features are required. Knowledge gained from these studies is often available in the form of graphs, and their visualization is especially useful in a wide range of systems biology topics, including pathway analysis, interaction networks or gene models. Especially, it is necessary to compare biological models with measured data. This allows the identification of new models and new insights into existing ones. Results: We present MGV, a versatile generic graph viewer for multiomics data. MGV is integrated into Mayday (Battke et al., 2010). It extends Maydays visual...

2011-01-01

258

Biological wound dressings sterilized with gamma radiation: Mexican clinical experience

British Library Electronic Table of Contents (United Kingdom)

Biological wound dressings sterilized with gamma radiation, such as amnion and pig skin, are a reality in Mexico. These tissues are currently processed in the tissue bank and sterilized in the Gamma Industrial Irradiation Plant; both facilities belong to the Instituto Nacional de Investigaciones Nucleares (ININ) (National Institute of Nuclear Research). With the strong support of the International Atomic Energy Agency, the bank was established at the ININ and the Mexican Ministry of Health issued its sanitary license on July 7, 1999. The Quality Management System of the bank was certified by ISO 9001:2000 on August 1, 2003; the scope of the system is "Research, Development and Processing of Biological Tissues Sterilized with Gamma Radiation". At present, more than 150 patients from 16 hosp...

2007-01-01

259

Biological scarcity: looking beyond regulatory exteriors in Taiwan

British Library Electronic Table of Contents (United Kingdom)

Research and bioethical policies are increasingly seen to facilitate, rather than to impede, scientific progress. Bioethical structures, nonetheless, often fail to account for or to shape the specific social surrounds in which scientific research is conducted. In Taiwan, a perceived shortage in human biological donations threatens to hamper stem cell research progress. This paper considers the stalled national biobank project and the lack of a reliable embryo supply for stem cell research, and suggests that one must look beyond regulatory structures in seeking explanations for such shortages. Specific aspects of Taiwan's democratization and social changes combine with problematic relations between patients and physicians to shape the terrain upon which human biologicals are given or withhe...

2011-01-01

260

Applications of CR-39 for the estimation of biological effects of heavy ion irradiation to DNA and living cells

Variability of the physical properties of tuff at Yucca Mountain, NV

We present two applications of CR-39 to estimate biological effects of heavy ion irradiation. The accurate measurement of fluence of ions using CR-39 is indispensable to calculate the action cross sections for biological effects. Ions with 6 MeV/n at the Medium Energy Beam Course, HIMAC (NIRS) were extracted to the air, and degraded with the air. DNA and living cells were irradiated by ions with various specific energies at several air columns along with the Bragg curve. DNA strand breaks and cell killing were measured and the results were converted to the action cross sections using the fluence measured with CR-39 at the irradiation positions. Another example of the application of CR-39 is to identify whether the ions with a specific energy pass through the cell or stop within the cell. (author)

2001-10-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

261

Polyp measurement based on CT colonography and colonoscopy: variability and systematic differences

Lateral and vertical variabilities in the bulk and mechanical properties of silicic volcanic tuff at the potential nuclear waste repository site in Yucca Mountain, NV have been evaluated. Laboratory measurements have been performed on tuff specimens recovered from boreholes located to support the design of the Exploratory Studies Facility/North Ramp. The data include dry and saturated bulk densities, average grain density, porosity, compressional and shear wave velocities, elastic moduli, and compressional and tensional fracture strengths. Data from eight boreholes aligned in a northwest-southeast direction have been collected under the required quality assurance program. Three boreholes have penetrated the potential repository horizon. The information collected provides for an accurate appraisal of the variability of rock properties in the vicinity of the boreholes. As expected, there is substantial variability in the bulk ...

1994-12-31

262

Whole-genome cancer analysis as an approach to deeper understanding of tumour biology

To assess the variability and systematic differences in polyp measurements on optical colonoscopy and CT colonography. Gastroenterologists measured 51 polyps by visual estimation, forceps comparison and linear probe. CT colonography observers randomly assessed polyp size two-dimensionally (abdominal and intermediate window) and three-dimensionally (manually and semi-automatically). Linear mixed models were used to assess the variability and systematic differences between CT colonography and optical colonoscopy techniques. The variability of forceps and linear probe measurements was comparable and both showed less variability than measurement by visual assessment. Measurements by linear probe were 0.7 mm smaller than measurements by visual assessment or by forceps. The variability of all CT colonography techniques was lower than for measurements by forceps or visual assessment and ...

2010-06-15

263

Value of procalcitonin, C-reactive protein, and neopterin in exacerbations of chronic obstructive pulmonary disease

Recent advances in DNA sequencing technology are providing unprecedented opportunities for comprehensive analysis of cancer genomes, exomes, transcriptomes, as well as epigenomic components. The integration...Full Text Available

2010-01-19

264

Using long term biological monitoring data to evaluate the recovery of disturbed systems

Objective:The identification of biological markers in order to assess different aspects of COPD is an area of growing interest. The objective of this study was to investigate whether...Full Text Available

2011-01-01

265

Uracil DNA glycosylase uses DNA hopping and short-range sliding to trap extrahelical uracils

Biological monitoring has been conducted in industrially impacted streams near US Department of Energy facilities in Tennessee and Kentucky for almost ten years. A comprehensive Biological Monitoring and Abatement Program, which was developed to meet National Pollutant Discharge Elimination System permit requirements, includes tasks on (1 ) toxicity testing; (2) bioaccumulation in aquatic and terrestrial biota; (3) bioindicators of fish health; and (4) fish, macroinvertebrate, and periphyton community surveys. These studies have been used successfully to characterize spatial trends and demonstrate temporal recovery resulting from remedial actions and pollution abatement activities, identify contaminant sources, and provide data for conducting ecological risk assessments. The program uses multiple lines of evidence to evaluate stream recovery and illustrates the importance of using an integrated approach when determining stream health. An ...

1995-11-05

266

Undergraduate Course and Curriculum Development Program and Curriculum Development in Mathematics: Calculus and the Bridge to Calculus 1994 Awards

The astonishingly efficient location and excision of damaged DNA bases by DNA repair glycosylases is an especially intriguing problem in biology. One example is the enzyme uracil DNA glycosylase (UNG),...Full Text Available

2008-08-05

267

Two-site exchange revisited: a new method for extracting exchange parameters in biological systems.

... such as biology, physics, geology, materials science, engineering, computer science, and mathematics ... expected to produce course and curricular materials that will be of national interest and widely ...

268

Tissue Effect on Genetic Control of Transcript Isoform Variation

A new analysis is presented which links real volume fractions, relaxation rates, and intracompartmental exchange rates directly with apparent volume fractions and relaxation rates obtained from biexponential...Full Text Available

1989-02-01

269

The hemoglobins of the trematodes Fasciola hepatica and Paramphistomum epiclitum: A molecular biological, physico-chemical, kinetic, and vaccination study

Current genome-wide association studies (GWAS) are moving towards the use of large cohorts of primary cell lines to study a disease of interest and to assign biological relevance to the genetic signals...Full Text Available

2009-08-01

270

The fission yeast gene pmt1+ encodes a DNA methyltransferase homologue.

The trematode Fasciola hepatica (Fa.he.) is a common parasite of human and livestock. The hemoglobin (Hb) of Fa.he., a potential immunogen, was chosen for characterization...Full Text Available

2008-10-01

271

The biological and clinical significance of HCG-containing cells in seminoma.

DNA methylation of cytosine residues is a widespread phenomenon and has been implicated in a number of biological processes in both prokaryotes and eukaryotes. This methylation occurs at the 5-position...Full Text Available

1995-01-25

272

The Anti-Inflammatory Drug Leflunomide Is an Agonist of the Aryl Hydrocarbon Receptor

The morphological appearance, incidence and prognostic significance of human chorionic gonadotrophin (HCG)-containing cells in seminomas were examined in a retrospective series of 228 orchidectomy specimens,...Full Text Available

1985-04-01

273

Temperature regulates limb length in homeotherms by directly modulating cartilage growth

BackgroundThe aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that mediates the toxicity and biological activity of dioxins and related chemicals. The...Full Text Available

274

Technological and biological reclamation of overburden dumps in NCL

Allen's Rule documents a century-old biological observation that strong positive correlations exist among latitude, ambient temperature, and limb length in mammals. Although genetic selection for thermoregulatory...Full Text Available

2008-12-09

275

Task-Specific Codes for Face Recognition: How they Shape the Neural Representation of Features for Detection and Individuation

Methods and materials employed by NCL to reclaim treatment of overburden dumps in opencast projects are described. These involve controlling slope stability and erosion (for example by covering with geosynthetic composites or jute/coir mat) and installing a drainage system before planting trees, shrubs and grass. 1 photo.

2000-05-01

276

TOXICITY OF AROMATIC AEROBIC BIOTRANSFORMATION PRODUCTS OF TOLUENE TO HELA CELLS

BackgroundThe variety of ways in which faces are categorized makes face recognition challenging for both synthetic and biological vision systems. Here we focus on two face processing...Full Text Available

277

Sugarcane pests and their management

Petroleum contamination of groundwater is widely recognized as a serious environmental problem. Toluene (methylbenzene) occurs naturally in crude oil and is commonly found as a contaminant in the subsurface as a result of waste disposal and storage activities. Biological transf...

278

Succession of Indigenous Pseudomonas spp. and Actinomycetes on Barley Roots Affected by the Antagonistic Strain Pseudomonas fluorescens DR54 and the Fungicide Imazalil

This book chapter discusses sugarcane culture and history, describes arthropod biologies and injury, and identifies sugarcane pest management factors to consider for people interested in commercial sugarcane production. Arthropod groups include 10 orders and 40 families. Sugarcane pest management ...

279

Structure of lipid bilayers

In recent years, the interest in the use of bacteria for biological control of plant-pathogenic fungi has increased. We studied the possible side effects of coating barley seeds with the antagonistic...Full Text Available

2001-03-01

280

Structural, chemical and biological aspects of antioxidants for strategies against metal and metalloid exposure

The quantitative experimental uncertainty in the structure of fully hydrated, biologically relevant, fluid (L_α) phase lipid bilayers has been too large to...Full Text Available

2000-11-10

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281

Sp1/NF?B/HDAC/miR-29b Regulatory Network in KIT-driven Myeloid Leukemia

Oxidative stress contributes to the pathophysiology of exposure to heavy metals/metalloid. Beneficial renal effects of some medications, such as chelation therapy depend at least partially on the ability...Full Text Available

2009-09-01

282

Shelterin complex and associated factors at human telomeres

SUMMARYThe biologic and clinical significance of KIT overexpression that associates with KIT gain-of- function mutations occurring in subsets...Full Text Available

2010-04-13

283

Seasonal and Annual Variation in Activity in Wild Male Meadow Voles (Microtus Pennsylvanicus).

The processes regulating telomere function have major impacts on fundamental issues in human cancer biology. First, active telomere maintenance is almost always required for full oncogenic transformation...Full Text Available

2011-03-01

284

SWISS MADE: Standardized WithIn Class Sum of Squares to Evaluate Methodologies and Dataset Elements

Project ZEUS was designed to characterize the effects of long-term gamma irradiation on free-ranging meadow voles, and to determine the lowest level of radiation at which biological effects are discernible in the population. Behavioural tests are consider...

1980-01-01

285

SEQADAPT: an adaptable system for the tracking, storage and analysis of high throughput sequencing experiments

Contemporary high dimensional biological assays, such as mRNA expression microarrays, regularly involve multiple data processing steps, such as experimental processing, computational processing, sample...Full Text Available

286

Room climate - air quality - thermal comfort; Raumklima - Luftqualitaet - Behaglichkeit

BackgroundHigh throughput sequencing has become an increasingly important tool for biological research. However, the existing software systems for managing and processing these data...Full Text Available

287

Role of copper resistance in competitive survival of Pseudomonas fluorescens in soil.

The article presents measures for the solution of construction-biological problems and for reducing the pollutant load of buildings. (HW) [Deutsch] Der Artikel berichtet ueber Massnahmen ueber Sanierung von baubiologischen Schwachstellen und Schadstoffbelastungen in Gebaeuden. (HW)

1995-12-31

288

Robust parameter extraction for decision support using multimodal intensive care data

A copper-resistant strain (09906) of Pseudomonas fluorescens that was isolated from a citrus grove soil is being investigated as a biological control agent for Phytophthora root rot. Since citrus grove...Full Text Available

1993-02-01

289

Research and development of a new RF-assisted device for bloodless rapid transection of the liver: Computational modeling and in vivo experiments

Digital information flow within the intensive care unit (ICU) continues to grow, with advances in technology and computational biology. Recent developments in the integration and archiving of these...Full Text Available

2009-01-28

290

Regulatory compliance | Mott MacDonald

BackgroundEfficient and safe transection of biological tissue in liver surgery is strongly dependent on the ability to address both parenchymal division and hemostasis simultaneously....Full Text Available

291

Wastenet

...broad range of experience in designing and building research and development laboratories for products such as vaccines, blood and sera, biological products, medical devices, solid dosage forms , highly potent products and cytotoxic material. We also have experience in a range of modular laboratories for TSE research, ...

292

Quantification of physical and biological uncertainty in the simulation of the yield of a tropical crop using present-day and doubled CO₂ climates

Quantification and deconvolution of asymmetric LC-MS peaks using the bi-Gaussian mixture model and statistical model selection

The impacts of climate change on crop productivity are often assessed using simulations from a numerical climate model as an input to a crop simulation model. The precision of these predictions reflects...Full Text Available

2005-11-29

293

Purpose and regulation of stem cells: a systems-biology view from the Caenorhabditis elegans germ line

BackgroundLiquid chromatography-mass spectrometry (LC-MS) is one of the major techniques for the quantification of metabolites in complex biological samples. Peak modeling is one...Full Text Available

294

Proteome of human colon cancer stem cells: A comparative analysis

Stem cells are expected to play a key role in the development and maintenance of organisms, and hold great therapeutic promises. However, a number of questions must be answered to achieve an...Full Text Available

2009-01-01

295

Project resumes: biological effects from electric fields associated with high-voltage transmission lines

AIM: To isolate and identify the biological characteristics of human colon cancer stem cells (SW1116 cells) and further study their proteome.METHODS: SW1116 cells were isolated and cultured with...Full Text Available

2011-03-14

296

Progress in osteoporosis and fracture prevention: focus on postmenopausal women

Abstracts of research projects are presented in the following areas: measurements and special facilities; cellular and subcellular studies; physiology; behavior; environmental effects; modeling, scaling and dosimetry; and high voltage direct current. (ACR)

1980-01-01

297

Prediction of breast cancer prognosis using gene set statistics provides signature stability and biological context

In the past decade, we have witnessed a revolution in osteoporosis diagnosis and therapeutics. This includes enhanced understanding of basic bone biology, recognizing the severe consequences of fractures...Full Text Available

2009-01-01

298

Predicting Protein Post-translational Modifications Using Meta-analysis of Proteome Scale Data Sets*S?

BackgroundDifferent microarray studies have compiled gene lists for predicting outcomes of a range of treatments and diseases. These have produced gene lists that have little overlap,...Full Text Available

299

Physical Activity and Telomere Biology: Exploring the Link with Aging-Related Disease Prevention

Protein post-translational modifications are an important biological regulatory mechanism, and the rate of their discovery using high throughput techniques is rapidly increasingly. To make use of this...Full Text Available

2009-02-01

300

Pathogenic Role of NKT and NK Cells in Acetaminophen-Induced Liver Injury is Dependent on the Presence of DMSO

Physical activity is associated with reduced risk of several age-related diseases as well as with increased longevity in both rodents and humans. Though these associations are well established, evidence...Full Text Available

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301

Partial Purification and Characterization of Biological Effects of a Lipid Toxin Produced by Mycobacterium ulcerans

Dimethyl sulfoxide (DMSO) is commonly used in biological studies to dissolve drugs and enzyme inhibitors with low solubility. While DMSO is generally thought of as being relatively inert, it...Full Text Available

2008-09-01

302

Parallel Arrays of Geometric Nanowells for Assembling Curtains of DNA with Controlled Lateral Dispersion

Organisms in the genus Mycobacterium cause a variety of human diseases. One member of the genus, M. ulcerans, causes a necrotizing skin disease called Buruli ulcer....Full Text Available

1998-02-01

303

PASBio: predicate-argument structures for event extraction in molecular biology

The analysis of individual molecules is evolving into an important tool for biological research, and presents conceptually new ways of approaching experimental design strategies. However, more...Full Text Available

2008-10-07

304

Overcoming the challenges of membrane protein crystallography

BackgroundThe exploitation of information extraction (IE), a technology aiming to provide instances of structured representations from free-form text, has been rapidly growing within...Full Text Available

305

On the sensitivity of IMRT dose optimization to the mathematical form of a biological imaging-based prescription function

Membrane protein structural biology is still a largely unconquered area, given that approximately 25% of all proteins are membrane proteins and yet less than 150 unique structures are available. Membrane...Full Text Available

2008-10-01

306

Natural Variation of Drug Susceptibility in Wild-Type Human Immunodeficiency Virus Type 1

Voxel-based prescriptions of deliberately non-uniform dose distributions based on molecular imaging, so-called dose painting or theragnostic radiation therapy, require specification of a transformation...Full Text Available

2009-03-21

307

Multilevel support vector regression analysis to identify condition-specific regulatory networks

Wild-type viruses from the ViroLogic phenotype-genotype database were evaluated to determine the upper confidence limit of the drug susceptibility distributions, or “biological cutoffs,”...Full Text Available

2004-02-01

308

Molecular biological enhancement of coal biodesulfurization. Final report, October 1988--December 1991

Motivation: The identification of gene regulatory modules is an important yet challenging problem in computational biology. While many computational methods have been proposed to identify...Full Text Available

2010-06-01

309

Molar extinction coefficients of some biologically important substances

The overall objective of this project was to use molecular genetics to develop strains of bacteria with enhanced ability to remove sulfur from coal, and to obtain data that will allow the performance and economics of a coal biodesulfurization process to be predicted. (VC)

1991-12-01

310

Modeling RNA polymerase competition: the effect of ?-subunit knockout and heat shock on gene transcription level

Reliable values of x-ray and gamma-ray attenuation coefficients of elements and compounds are required in spectrometry as well as in many other scientific, engineering and medical disciplines involving photon radiation

2002-11-15

311

Metabolic Engineering of Poly(3-Hydroxyalkanoates): From DNA to Plastic

BackgroundModeling of a complex biological process can explain the results of experimental studies and help predict its characteristics. Among such processes is transcription in...Full Text Available

312

Memories of John N. Brady: scientist, mentor and friend

Poly(3-hydroxyalkanoates) (PHAs) are a class of microbially produced polyesters that have potential applications as conventional plastics, specifically thermoplastic elastomers. A wealth of biological...Full Text Available

1999-03-01

313

Massive turnover of functional sequence in human and other mammalian genomes

Friends and colleagues remember John N. Brady, Ph.D., Chief of the Virus Tumor Biology Section of the Laboratory of Cellular Oncology, who died much too young at the age of 57 on April 27, 2009 of colon...Full Text Available

314

Mammalian Sirt1: insights on its biological functions

Despite the availability of dozens of animal genome sequences, two key questions remain unanswered: First, what fraction of any species' genome confers biological function, and second, are apparent...Full Text Available

2010-10-01

315

Long-term effects of inhaled uranyl nitrate in rats

Sirt1 (member of the sirtuin family) is a nicotinamide adenosine dinucleotide (NAD)-dependent deacetylase that removes acetyl groups from various proteins. Sirt1 performs a wide variety of functions...Full Text Available

316

Large-scale Analysis of Thermo-stable, Mammalian Proteins Provides Insights into the Intrinsically Disordered Proteome

Rats were exposed to aerosols of "2"3"3U and "2"3"2U nitrate in a study of the long-term biological effects. Preliminary radiation dose estimates show lung > skeleton > kidney in each dose group.

1977-05-01

317

Intrinsic near-24-h pacemaker period determines limits of circadian entrainment to a weak synchronizer in humans

Intrinsically disordered proteins are predicted to be highly abundant and play broad biological roles in eukaryotic cells. In particular, by virtue of their structural malleability and propensity...Full Text Available

2009-01-01

318

IntelliGO: a new vector-based semantic similarity measure including annotation origin

Endogenous circadian clocks are robust regulators of physiology and behavior. Synchronization or entrainment of biological clocks to environmental time is adaptive and important for physiological homeostasis...Full Text Available

2001-11-20

319

Integrase-directed recovery of functional genes from genomic libraries

BackgroundThe Gene Ontology (GO) is a well known controlled vocabulary describing the biological process, molecular function and cellular...Full Text Available

320

Insecticidal properties of genetically engineered baculoviruses expressing an insect juvenile hormone esterase gene.

Large population sizes, rapid growth and 3.8 billion years of evolution firmly establish microorganisms as a major source of the planet's biological and genetic diversity. However, up to 99% of the...Full Text Available

2009-09-01

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321

Inferring Stabilizing Mutations from Protein Phylogenies: Application to Influenza Hemagglutinin

Exploring the possibility of enhancing the properties of baculoviruses as biological control agents of insect pests, we tested the effect of expressing an insect gene (jhe) encoding juvenile hormone...Full Text Available

1992-05-01

322

In Vivo RNAi Screening Identifies Regulators of Actin Dynamics as Key Determinants of Lymphoma Progression

One selection pressure shaping sequence evolution is the requirement that a protein fold with sufficient stability to perform its biological functions. We present...Full Text Available

2009-04-01

323

Impact of concomitant use of DMARDs on the persistence with anti-TNF therapies in patients with rheumatoid arthritis: results from the British Society for Rheumatology Biologics Register

Mouse models have dramatically improved our understanding of cancer development and tumor biology. However, these models have shown limited efficacy as tractable systems for unbiased genetic...Full Text Available

2009-10-01

324

Identification of Phloem Involved in Assimilate Loading in Leaves by the Activity of the Galactinol Synthase Promoter1

ObjectiveTo evaluate the effect of different concomitant disease modifying antirheumatic drugs (DMARDs) on the persistence with antitumour necrosis factor (anti-TNF) therapies in...Full Text Available

325

Identification and validation of heavy metal and radionuclide hyperaccumulating terrestrial plant species. Quarterly technical progress report, March 20, 1995--June 20, 1995

The definition of “minor” veins in leaves is arbitrary and of uncertain biological significance. Generally, the term refers to the smallest vein classes in the leaf, believed to function...Full Text Available

2000-07-01

326

Identification and In Vivo Characterization of NvFP-7R, a Developmentally Regulated Red Fluorescent Protein of Nematostella vectensis

The biological accumulation of heavy metals and cesium, strontium, and uranium in plants is discussed. The role of nutrient deficiencies and foliar treatments of manganese and iron compounds is described.

1995-12-01

327

INVERTEBRATE FAUNA ASSOCIATED WITH TORPEDOGRASS, PANICUM REPENS (CYPERALES: POACEAE), IN LAKE OKEECHOBEE, FLORIDA, AND ...

BackgroundIn recent years, the sea anemone Nematostella vectensis has emerged as a critical model organism for comparative genomics and developmental biology. Although...Full Text Available

328

Human hair genealogies and stem cell latency

... 154. By way of comparison, the aquatic weed Hygrophila polysperma (Roxb.) T. Anderson, a potential target for biological ... L. Sutton. 2000. Is the aquatic weed hygrophila, Hygrophila polysperma (Polemon...

329

Highly Conserved Regimes of Neighbor-Base-Dependent Mutation Generated the Background Primary-Structural Heterogeneities along Vertebrate Chromosomes

BackgroundStem cells divide to reproduce themselves and produce differentiated progeny. A fundamental problem in human biology has been the inability to measure how often stem cells...Full Text Available

330

Gyrase B Inhibitor Impairs HIV-1 Replication by Targeting Hsp90 and the Capsid Protein*

The content of guanine+cytosine varies markedly along the chromosomes of homeotherms and great effort has been devoted to studying this heterogeneity and its biological implications. Already...Full Text Available

331

Genome-Wide Identification and Evolutionary Analysis of the Animal Specific ETS Transcription Factor Family

Chemical genetics is an emerging approach to investigate the biology of host-pathogen interactions. We screened several inhibitors of ATP-dependent DNA motors and detected the gyrase B inhibitor coumermycin...Full Text Available

2010-12-10

332

Genetic aspects of birth defects: new understandings of old problems

The ETS proteins are a family of transcription factors (TFs) that regulate a variety of biological processes. We made genome-wide analyses to explore the classification of the ETS gene family. We identified...Full Text Available

333

Gallium Disrupts Iron Uptake by Intracellular and Extracellular Francisella Strains and Exhibits Therapeutic Efficacy in a Murine Pulmonary Infection Model ?

Over the past two decades, combined advances in genetics, developmental biology and biochemistry have transformed the study of human birth defects. This review describes the importance of genome architecture,...Full Text Available

2007-07-01

334

Fusion expression of pedA gene to obtain biologically active pediocin PA-1 in Escherichia coli *

Francisella tularensis requires iron (Fe) for growth, but the biologic sources of Fe for this organism are largely unknown. We found that Francisella sp. growing in...Full Text Available

2010-01-01

335

From Classical Genetics to Quantitative Genetics to Systems Biology: Modeling Epistasis

Two heterologous expression systems using thioredoxin (trxA) as a gene fusion part in Escherichia coli were developed to produce recombinant pediocin PA-1. Pediocin...Full Text Available

2011-01-01

336

Fabp7 Maps to a Quantitative Trait Locus for a Schizophrenia Endophenotype

Gene expression data has been used in lieu of phenotype in both classical and quantitative genetic settings. These two disciplines have separate approaches to measuring and interpreting epistasis, which...Full Text Available

2008-03-01

337

Experimental Differential Light-Scattering Correction to the Circular Dichroism of Bacteriophage T2

Deficits in prepulse inhibition (PPI) are a biological marker for schizophrenia. To unravel the mechanisms that control PPI, we performed quantitative trait loci (QTL) analysis on 1,010 F2 mice derived...Full Text Available

2007-11-01

338

Evolutionary history and the effect of biodiversity on plant productivity

Experimental techniques are presented that can be used to assay and correct for differential light scattering effects in circular dichroism spectra of biological macrostructures. The assay is based...Full Text Available

1973-01-01

339

Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses

Loss of biological diversity because of extinction is one of the most pronounced changes to the global environment. For several decades, researchers have tried to understand how changes in biodiversity...Full Text Available

2008-11-04

340

Estimating trace deposition time with circadian biomarkers: a prospective and versatile tool for crime scene reconstruction

DNA double-strand breaks (DSBs) are generally accepted to be the most biologically significant lesion by which ionizing radiation causes cancer and hereditary disease. However, no information on the...Full Text Available

2003-04-29

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341

Estimating Impact Forces of Tail Club Strikes by Ankylosaurid Dinosaurs

Linking biological samples found at a crime scene with the actual crime event represents the most important aspect of forensic investigation, together with the identification of the sample donor. While...Full Text Available

2010-09-01

342

Environmental assessment of the Alaskan continental shelf. Final reports of principal investigators, Volume 15. Biological studies

BackgroundIt has been assumed that the unusual tail club of ankylosaurid dinosaurs was used actively as a weapon, but the biological feasibility of this behaviour has not been examined...Full Text Available

343

Engineering ligand-responsive RNA controllers in yeast through the assembly of RNase III tuning modules

The contents of the report include: Identification, documentation and delineation of coastal migratory bird habitat; and an annotated bibliography of literature on Alaska Water Birds.

1981-12-01

344

Endocrine and Neurochemical Effects of 3,4-Methylenedioxymethamphetamine and Its Stereoisomers in Rhesus Monkeys

The programming of cellular networks to achieve new biological functions depends on the development of genetic tools that link the presence of a molecular signal to gene-regulatory activity. Recently,...Full Text Available

2011-07-01

345

Emerging diseases in Chiroptera: why bats?

3,4-Methylenedioxymethamphetamine (MDMA) is an amphetamine derivative that elicits complex biological effects in humans. One plausible mechanism for this phenomenon is that racemic MDMA is composed...Full Text Available

2010-08-01

346

Emergence of Switch-Like Behavior in a Large Family of Simple Biochemical Networks

A conference entitled ‘2nd International Berlin Bat Meeting: Bat Biology and Infectious Diseases’ was held between the 19 and 21 of February 2010 in Berlin, Germany. Researchers from...Full Text Available

2010-08-23

347

Efficient Phagocytosis Requires Triacylglycerol Hydrolysis by Adipose Triglyceride Lipase*

Bistability plays a central role in the gene regulatory networks (GRNs) controlling many essential biological functions, including cellular differentiation and cell cycle control. However, establishing...Full Text Available

2011-05-01

348

Dynamics of ligand substitution in labile cobalt complexes resolved by ultrafast T-jump

Macrophage phagocytosis is an essential biological process in host defense and requires large amounts of energy. To date, glucose is believed to represent the prime substrate for ATP production in macrophages....Full Text Available

2010-06-25

349

Discovering Networks of Perturbed Biological Processes in Hepatocyte Cultures

Ligand exchange of hydrated metal complexes is common in chemical and biological systems. Using the ultrafast T-jump, we examined this process, specifically the transformation of aqua cobalt (II) complexes...Full Text Available

2008-09-02

350

Differential Regulation of PDE5 Expression in Left and Right Ventricles of Feline Hypertrophy Models

The liver plays a vital role in glucose homeostasis, the synthesis of bile acids and the detoxification of foreign substances. Liver culture systems are widely used to test adverse effects of drugs...Full Text Available

351

DECOMP: A PDB decomposition tool on the web

BackgroundThough long known to affect smooth muscle biology, recent studies indicate that phosphodiesterase 5 (PDE5) is also expressed in myocardium. Recognizing that the regulation...Full Text Available

352

Curcumin, a cancer chemopreventive and chemotherapeutic agent, is a biologically active iron chelator

The protein databank (PDB) contains high quality structural data for computational structural biology investigations. We have earlier described a fast tool (the decomp_pdb tool) for identifying and...Full Text Available

353

Cumulative effects of protracted irradiation of Chernobyl exclusive zone plants

Curcumin is a natural product currently in human clinical trials for a variety of neoplastic, preneoplastic, and inflammatory conditions. We previously observed that, in cultured cells, curcumin exhibits...Full Text Available

2009-01-08

354

Cumulative Inflammatory Load Is Associated with Short Leukocyte Telomere Length in the Health, Aging and Body Composition Study

The biological and radiobiological peculiarities of seeds and seedlings of the Rumex confertus and Lupinus polycolor plants, which grown during several generations in plots with different level of radionuclide pollution of the Chernobyl exclusive zone have been investigated.

2005-01-01

355

Crystallization and preliminary X-ray analysis of human liver ?-enolase

BackgroundLeukocyte telomere length (LTL) is an emerging marker of biological age. Chronic inflammatory activity is commonly proposed as a promoter of ...Full Text Available

356

Cryptic invasion by a non-native genotype of the common reed, Phragmites australis, into North America

Enolase is a multifunctional enzyme that plays important roles in many biological and disease processes. α-Enolase from human liver (hENO1) was expressed as a soluble protein and purified by...Full Text Available

357

Computational Challenges in miRNA Target Predictions: To Be or Not to Be a True Target?

Cryptic invasions are a largely unrecognized type of biological invasion that lead to underestimation of the total numbers and impacts of invaders because of the difficulty in detecting them. The distribution...Full Text Available

2002-02-19

358

Comparative analysis of RBE values of two sublines of the Dunning prostate tumor R3327 using different biological characteristics; Vergleichende Bestimmung der RBE - Werte fuer zwei Sublinien des Dunning Prostatatumors R3327 mit unterschiedlichen biologischen Charakterisitika

All microRNA (miRNA) target—finder algorithms return lists of candidate target genes. How valid is that output in a biological setting? Transcriptome analysis has proven to be a useful approach...Full Text Available

2009-01-01

359

Coevolution of activating and inhibitory receptors within mammalian carcinoembryonic antigen families

Short communication

1995-12-31

360

Climate change induces demographic resistance to disease in novel coral assemblages

BackgroundMost rapidly evolving gene families are involved in immune responses and reproduction, two biological functions which have been assigned to the carcinoembryonic antigen...Full Text Available

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361

Chromosome aberrations in human lymphocytes from the plateau region of the Bragg curve for a carbon-ion beam

Climate change is reshaping biological communities and has already generated novel ecosystems. The functioning of novel ecosystems could depart markedly from that of existing systems and therefore obscure...Full Text Available

2011-02-01

362

Chemotherapy-induced alopecia in mice. Induction by cyclophosphamide, inhibition by cyclosporine A, and modulation by dexamethasone.

Radiotherapy with high-energy carbon ion beams can be more advantageous compared to photons because of better physical dose distribution and higher biological efficiency in tumour cell sterilization. Despite enhanced normal tissue sparing, damage incurred by normal cells at the beam entrance is unavoidable and may affect the progeny of surviving cells in the form of inheritable cytogenetic alterations. Furthermore, the quality of the beam along the Bragg curve is modified by nuclear fragmentation of projectile and target nuclei in the body. We present an experimental approach based on the use of a polymethylmethacrylate (PMMA) phantom that allows the simultaneous exposure to a particle beam of several biological samples positioned at various depths along the beam path. The device was used to measure the biological effectiveness of a 60 MeV/amu carbon-ion beam at inducing chromosomal aberrations in G{sub 0}-human peripheral ...

2007-06-15

363

Calculations of physical and chemical reactions produced in irradiated water containing DNA

We introduce cyclophosphamide-induced alopecia (CYP-IA) in C57BL-6 mice as a clinically relevant model for studying the biology of chemotherapy-induced alopecia and for developing anti-alopecia drugs....Full Text Available

1994-04-01

364

Boule and the Evolutionary Origin of Metazoan Gametogenesis: A Grandpa's Tale

Initial results obtained with a Monte Carlo computer program designed to link initial physical events in irradiated liquid water with subsequent chemical and biological events are presented. 10 refs., 4 figs., 3 tabs.

1985-01-01

365

Biology and Medicine Division annual report, 1978-1979

The evolution of sex remains a hotly debated topic in evolutionary biology. In particular, studying the origins of the molecular mechanisms underlying sexual reproduction and gametogenesis (its fundamental...Full Text Available

366

Biology and Effects of Spontaneous Heating in Hay

Summaries of research projects conducted during 1978 and 1979 are presented. Subject areas include research medicine, cancer research, environmental physiology, radiation biophysics, and structural biophysics. (ACR)

1979-01-01

367

Biological, Life Course, and Cross-Cultural Studies All point Toward the Value of Dimensional and Developmental Ratings in the Classification of Psychosis

The negative consequences of baling hay before it is adequately dried are widely known to producers. Frequently, these problems are created by uncooperative weather conditions that prevent forages from drying (rapidly) to moisture levels that allow safe and stable storage of harvested forages. When ...

368

Biological wound dressings sterilized with gamma radiation: Mexican clinical experience

The diagnostic criteria for schizophrenia in the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV1)...Full Text Available

2007-07-01

369

Biological variations in Anopheles darlingi and Anopheles gambiae

Biological wound dressings sterilized with gamma radiation, such as amnion and pig skin, are a reality in Mexico. These tissues are currently processed in the tissue bank and sterilized in the Gamma Industrial Irradiation Plant; both facilities belong to the Instituto Nacional de Investigaciones Nucleares (ININ) (National Institute of Nuclear Research). With the strong support of the International Atomic Energy Agency, the bank was established at the ININ and the Mexican Ministry of Health issued its sanitary license on July 7, 1999. The Quality Management System of the bank was certified by ISO 9001:2000 on August 1, 2003; the scope of the system is 'Research, Development and Processing of Biological Tissues Sterilized with Gamma Radiation'. At present, more than 150 patients from 16 hospitals have been successfully treated with these tissues. This paper presents a brief description of the tissue processing, as well as the present Mexican ...

2007-11-01

370

Biological processing and interactions with coal: Summary of activities for the period January 1, 1988--March 31, 1988

A remarkable range of variation has been demonstrated in the biting habits of A. darlingi in South America. At the centre of its area of distribution, the species comprises both anthropo-endophilic...Full Text Available

1956-01-01

371

Biological effects of low level exposures to chemicals and radiation

Biodegradation/solubilization of coal is described. The degradation of dibenzothiophene by two bacterial strains is reported. The effects of adding salicylate to the treatments was also investigated. 2 figs., 5 tabs. (CBS)

1988-01-01

372

Biological conversion of synthesis gas: Quarterly report [No. 3-4, July 1, 1993--September 3, 1993

In May 1990 a group of scientists representing several federal agencies, the International Society of Regulatory Toxicology and Pharmacology, the private sector, and academia met to develop a strategy to encourage the study of the biological effects of low level exposures (BELLE) to chemical agents and radioactivity. A workshop was held in 1991 with seven invited speakers focusing on the toxicological implications of biological adaptations. The selection of topics and speakers was designed to consider critically the concept of hormesis, not only in a broad, conceptual manner, but also at the molecular and biochemical levels. These presentations offered a complementary perspective on the diverse range of molecular mechanisms that can become activated at low levels of toxicant exposure. In addition to chemical toxicology research, an overview of current research on 'Effects of low-dose radiation on the immune response' was presented as well as ...

373

Biological Response to Nonuniform Distributions of ²¹⁰Po in Multicellular Clusters

This report details the status of the Biological Conversion of Synthesis Gas Project. The following tasks are described as being completed: (1) the test plan, (2) culture development, and (3) the mass transfer/kinetic studies. The bioreactor studies (Task 4) are underway. The continuous stirred tank reactor system for the conversion of H{sub 2}S to elemental sulfur using Chlorobium thiosulfatophilum has been studied for varying light intensities. The system was also modified to include both sulfur recovery and cell recycle using ceramic membranes. Studies were also performed to observe the effects of cell recycle using a polysulfone hollow filter membrane module. Work on Task 5, limiting conditions/scale-up, includes a scale-up study with three different size reactors to establish the optimum operating conditions for hydrogen production from synthesis gas by the biological water-gas shift reaction using the photosynthetic bacterium ...

1993-10-01

374

Biological Response Modifier Activity of an Exopolysaccharide from Paenibacillus jamilae CP-7

Radionuclides are distributed nonuniformly in tissue. The present work examined the impact of nonuniformities at the multicellular level on the lethal effects of ²¹⁰Po. A three-dimensional...Full Text Available

2007-09-01

375

Biodiversity and body size are linked across metazoans

An extracellular polysaccharide was purified from culture supernatants of Paenibacillus jamilae CP-7, a gram-positive bacillus that was isolated from compost prepared with olive mill...Full Text Available

2001-07-01

376

Bioaccumulation and toxicity of selenium compounds in the green alga Scenedesmus quadricauda

Body size variation across the Metazoa is immense, encompassing 17 orders of magnitude in biovolume. Factors driving this extreme diversification in size and the consequences of size variation for biological...Full Text Available

2009-06-22

377

Binary Bacterial Toxins: Biochemistry, Biology, and Applications of Common Clostridium and Bacillus Proteins

BackgroundSelenium is a trace element performing important biological functions in many organisms including humans. It usually affects organisms in a strictly dosage-dependent manner...Full Text Available

378

Association of Paraoxonase 1 (PON1) polymorphisms with osteoporotic fracture risk in postmenopausal Korean women

Certain pathogenic species of Bacillus and Clostridium have developed unique methods for intoxicating cells that employ the classic enzymatic “A-B” paradigm for protein toxins. The binary...Full Text Available

2004-09-01

379

Antioxidant Defenses Predict Long-Term Survival in a Passerine Bird

There is increasing evidence of a biochemical link between lipid oxidation and bone metabolism. Paraoxonase 1 (PON1) prevents the oxidation of low-density lipoprotein (LDL) and metabolizes biologically...Full Text Available

2011-02-28

380

Amyloid Oligomer Neurotoxicity, Calcium Dysregulation, and Lipid Rafts

BackgroundNormal and pathological processes entail the production of oxidative substances that can damage biological molecules and harm physiological functions. Organisms have evolved...Full Text Available

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381

Ammonium and Nitrate Uptake by the Floating Plant Landoltia punctata

Amyloid proteins constitute a chemically heterogeneous group of proteins, which share some biophysical and biological characteristics, the principal of which are the high propensity to acquire an incorrect...Full Text Available

382

Alteration of the chemical environment disrupts communication in a freshwater fish

Background and AimsPlants from the family Lemnaceae are widely used in ecological engineering projects to purify wastewater and eutrophic water bodies. However, the biology of nutrient...Full Text Available

2007-02-01

383

Actin Fusion Proteins Alter the Dynamics of Mechanically Induced Cytoskeleton Rearrangement

It is well established that changes to the chemical environment can impair development, physiology and reproductive biology; by contrast, impacts on communication have not been widely reported. This...Full Text Available

2006-05-22

384

Accelerated interleaflet transport of phosphatidylcholine molecules in membranes under deformation.

Mechanical forces can regulate various functions in living cells. The cytoskeleton is a crucial element for the transduction of forces in cell-internal signals and subsequent biological responses. Accordingly,...Full Text Available

385

AEROSPACE MEDICINE AND BIOLOGY - NASA Technical Reports Server

Biological membranes are lamellar structures composed of two leaflets capable of supporting different mechanical stresses. Stress differences between leaflets were generated during micromechanical experiments...Full Text Available

1996-09-01

386

A simple method to systematically study oxidatively-modified proteins in biological samples and its applications

Learning curve models have gained widespread acceptance as a technique for analyzing and ...... flight segment in F4 pilots p 163 A91-30966. WILSON, JOHN W . ...

387

A multistep bioinformatic approach detects putative regulatory elements in gene promoters

Increased oxidative stress with elevated levels of reactive oxygen and nitrogen species (ROS/RNS) plays an important role in the pathophysiology of many disease states. Increased ROS/RNS can...Full Text Available

2010-01-01

388

A biological standard for measurement of blood coagulation factor VIII activity

BackgroundSearching for approximate patterns in large promoter sequences frequently produces an exceedingly high numbers of results. Our aim was to exploit biological knowledge for...Full Text Available

389

A Vasculature-Targeting Regimen of Pre-Operative Docetaxel with or without Bevacizumab for Locally Advanced Breast Cancer

Because of the instability of Factor VIII (antihaemophilic factor) in plasma in vitro, and since evidence has accumulated that the level of activity varies significantly between samples...Full Text Available

1971-01-01

390

A Position Paper on the Electronic Publication of Nematode Taxonomic Manuscripts

PurposeTaxanes have effects on angiogenesis causing difficulties in separating biologic effects of chemotherapy from those due to angiogenesis inhibitors. This randomized...Full Text Available

2009-05-15

391

A Hot New Twist to Hair Biology

Several nematode species have now attained ‘model organism’ status, yet there remain many niches in basic biological inquiry for which nematodes would be ideal model systems of study....Full Text Available

2006-09-01

392

A Curated Database of miRNA Mediated Feed-Forward Loops Involving MYC as Master Regulator

The vanilloid receptor-1 (VR1, or transient receptor potential vanilloid-1 receptor, TRPV1) is activated by capsaicin, the key ingredient of hot peppers. TRPV1 was originally described on sensory neurons...Full Text Available

2005-04-01

393

A Comprehensive Analysis of the Dynamic Biological Networks in HCV Induced Hepatocarcinogenesis

BackgroundThe MYC transcription factors are known to be involved in the biology of many human cancer types. But little is known about the Myc/microRNAs cooperation in the regulation...Full Text Available

394

The effects of temperature dependent viscosity and thermal conductivity on unsteady MHD convective heat transfer past a semi-infinite vertical porous moving plate with variable suction

Hepatocellular carcinoma (HCC) is a primary malignancy of the liver, which is closely related to hepatitis C and cirrhosis. The molecular mechanisms underlying the hepatocarcinogenesis induced by HCV...Full Text Available

395

British Library Electronic Table of Contents (United Kingdom)

In this article, we studied the effects of variable viscosity and thermal conductivity on an unsteady two-dimensional laminar flow of a viscous incompressible conducting fluid past a semi-infinite vertical porous moving plate taking into account the effect of a magnetic field in the presence of variable suction. The fluid viscosity is assumed to vary as an inverse linear function of temperature but the thermal conductivity is assumed to vary as a linear function of temperature. It is assumed that the porous plate moves with a constant velocity in the direction of fluid flow, and the free stream velocity follows the exponentially increasing small perturbation law. The governing equations for the flow are transformed into a system of nonlinear ordinary differential equations by perturbation ...

2007-01-01

396

The coexistence of fish species in streams: relationships between assemblage attributes and trophic and environmental variables

British Library Electronic Table of Contents (United Kingdom)

Diet overlap and niche breadth are well-known species traits from trophic ecology that can assist in explaining how species interact and coexist as well as the ecological mechanisms that influence biodiversity. In the present study, we analyzed the relationships between these trophic variables and indicators of resource availability with some attributes of fish assemblages (species richness, Shannon diversity index, evenness, density and individual body size). The physical and chemical characteristics of the biotopes (topography, water quality and conservation of slopes) were examined to identify possible patterns. Monthly sampling using electrofishing was conducted in 2003 along five streams located in the Cuiab? River watershed. The relationships between environmental variables and attri...

2011-01-01

397

Powertrain and apparatus using a continuously variable ratio transmission to improve fuel economy

Power correlation for vertical axis wind turbines with varying geometries

An automotive powertrain includes a conventional piston engine, a continuously variable ratio transmission, an engine speed sensor and a feedback control system. The control system adjusts both the transmission ratio and the throttle valve in the engine carburetor or fuel metering system in response to the position of the accelerator pedal and in response to the crankshaft speed as measured by the engine sensor. The transmission provides extreme overdrive gear ratios which allow the engine to be operated at wide open throttle even during moderate cruising, and, in addition, the engine carburetor or fuel metering system is calibrated to deliver to the engine a stoichiometric air-fuel mixture which is combined, before combustion, with a special proportion of recirculated exhaust gas. As a result of extensive wide open throttle engine operation with the above mentioned intake charge composition, combustion variables are optimized to produce ...

1981-07-28

398

British Library Electronic Table of Contents (United Kingdom)

Abstract In this paper, a new predictive model that can forecast the performance of a vertical axis wind turbine (VAWT) is presented. The new model includes four primary variables (rotor velocity, wind velocity, air density, and turbine power output) as well as five geometrical variables (rotor radius, turbine height, turbine width, stator spacing, and stator angle). These variables are reduced to include the power coefficient (Cp) and tip speed ratio (TSR). A power coefficient correlation for a novel VAWT (called a Zephyr Vertical axis Wind Turbine (ZVWT)) is developed. The turbine is an adaptation of the Savonius design. The new correlation can predict the turbine's performance for altered stator geometry and varying operating conditions. Numerical simulations with a rotating reference f...

2011-01-01

399

Long and Short Distance Migration in Italy: The Role of Economic, Social and Environmental Characteristics

British Library Electronic Table of Contents (United Kingdom)

This paper analyses Italian interregional migration flows. The approach taken is to decompose labour mobility flows into short distance and long distance migration and to model the effects of economic variables, social capital and quality of life variables, and amenity variables, on the mobility behaviour of individuals. We estimate these different types of migration flows using a negative binomial model, augmented with instruments to control for potential endogeneity issues. Our findings demonstrate that long distance migration reflects a disequilibrium model of migration whereas short distance migration largely reflects an equilibrium model of migration. As such, attempts to model interregional migration in general will be mis-specified as the simultaneously-operating underlying mobility...

2011-01-01

400

Irreversible Performance of a Quantum Harmonic Heat Engine

Interannual relationships between Indian Summer Monsoon and Indo-Pacific coupled modes of variability during recent decades

The unavoidable irreversible losses of power in a heat engine are found to be of quantum origin. Following thermodynamic tradition a model quantum heat engine operating by the Otto cycle is analyzed. The working medium of the model is composed of an ensemble of harmonic oscillators. A link is established between the quantum observables and thermodynamical variables based on the concept of canonical invariance. These quantum variables are sufficient to determine the state of the system and with it all thermodynamical variables. Conditions for optimal work, power and entropy production show that maximum power is a compromise between the quasistatic limit of adiabatic following on the compression and expansion branches and a sudden limit of very short time allocation to these branches. At high temperatures and quasistatic operating conditions the efficiency at maximum power coincides with the endoreversible result. The optimal ...

2006-01-01

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401

British Library Electronic Table of Contents (United Kingdom)

Various SST indices in the Indo-Pacific region have been proposed in the literature in light of a long-range seasonal forecasting of the Indian Summer Monsoon (ISM). However, the dynamics associated with these different indices have never been compared in detail. To this end, the present work re-examines the variabilities of ISM rainfall, onset and withdrawal dates at interannual timescales and explores their relationships with El Ni?o-Southern Oscillation (ENSO) and various modes of coupled variability in the Indian Ocean. Based on recent findings in the literature, five SST indices are considered here: Ni?o3.4 SST index in December?January both preceding [Nino(?1)] and following the ISM [Nino(0)], South East Indian Ocean (SEIO) SST in February?March, the Indian Ocean Basin (IOB) mode in ...

2011-01-01

402

Experiences in batch trajectory alignment for pharmaceutical process improvement through multivariate latent variable modelling

British Library Electronic Table of Contents (United Kingdom)

The primary objective of batch data as trajectory alignment (or synchronization) is to standardize the data sampling per batch according to the evolution of the process, and secondarily to homogenize the samples per run. The use of an indicator variable performs both objectives well. Two examples from the pharmaceutical sector are discussed to illustrate the different ways to deal with uneven samples across batches and across variables in the same batch. Since trajectory alignment requires large time investment, a simple triage approach is proposed to assess the need to analyze the dynamics of a given process and hence perform alignment. The presented examples are representative of a broad variety of batch processes that are operated by recipe in the pharmaceutical sector. In our experienc...

2011-01-01

403

Enamel-Calibrated Lamellar Bone Reveals Long Period Growth Rate Variability in Humans

British Library Electronic Table of Contents (United Kingdom)

Abstract Mammalian teeth exhibit incremental structures representing successive forming fronts of enamel at varying time scales, including a short daily increment called a cross striation and a long period called a stria of Retzius, the latter of which, in humans, occurs on average every 8-9 days. The number of daily increments between striae is called the repeat interval, which is the same period as that required to form one increment of bone, i.e. the lamella, the fundamental - if not archetypal - unit of bone. Lamellae of known formation time nevertheless vary in width, and thus their measures provide time-calibrated growth rate variability. We measured growth rate variability for as many as 6 years of continuously forming primary incremental lamellar bone from midshaft femur histologic...

2011-01-01

404

Dirichlet mean identities and laws of a class of subordinators

Combined inverse modeling approach and load duration curve method for variable nitrogen total maximum daily load development in an agricultural watershed

An interesting line of research is the investigation of the laws of random variables known as Dirichlet means. However, there is not much information on interrelationships between different Dirichlet means. Here, we introduce two distributional operations, one of which consists of multiplying a mean functional by an independent beta random variable, the other being an operation involving an exponential change of measure. These operations identify relationships between different means and their densities. This allows one to use the often considerable analytic work on obtaining results for one Dirichlet mean to obtain results for an entire family of otherwise seemingly unrelated Dirichlet means. Additionally, it allows one to obtain explicit densities for the related class of random variables that have generalized gamma convolution distributions and the finite-dimensional distribution of their associated L\\'{e}vy processes. ...

2010-01-01

405

British Library Electronic Table of Contents (United Kingdom)

Purpose Nonpoint sources (NPS) pollution has been an important cause for water quality impairment worldwide. To take the temporal variations of both NPS pollution and in-stream attenuation into consideration, an inverse modeling approach and the load duration curve (LDC) method were combined for variable nutrient total maximum daily load (TMDL) development. Methods Water quality and hydrological parameters were monitored monthly along the ChangLe River system in 2004?2008. The catchment NPS export load (EL) and TMDL for total nitrogen (TN) were estimated by the inverse format of an existing stream nutrient transport equation. The LDC method was used to describe the variability of EL, TMDL, requiring load (RLR) and percent (the ratio between the RLR and the EL, RPR) reduction, and then to s...

2011-01-01

406

Characterizing the time variability in magnetized neutrino--cooled accretion disks: signatures of the gamma-ray burst central engine

Centennial climate variability in the British Isles during the mid-late Holocene

The central engine of Gamma Ray Bursts is hidden from direct probing with photons mainly due to the high densities involved. Inferences on their properties are thus made from their cosmological setting, energetics, low-energy counterparts and variability. If GRBs are powered by hypercritical accretion onto compact objects, on small spatial scales the flow will exhibit fluctuations, which could in principle be reflected in the power output of the central engine and ultimately in the high energy prompt emission. Here we address this issue by characterizing the variability in neutrino cooled accretion flows through local shearing box simulations with magnetic fields, and then convolving them on a global scale with large scale dynamical simulations of accretion disks. The resulting signature is characteristic, and sensitive to the details of the cooling mechanism, providing in principle a discriminant for GRB central engine properties.

2010-01-01

407

British Library Electronic Table of Contents (United Kingdom)

Multi-millennial climate changes were relatively minor over the mid-late Holocene in the British Isles, because orbitally forced insolation changes were smaller than those at higher latitudes. Centennial climate variability is thus likely to have exerted a greater influence on the environment and human society of the region. Proxy-climate records from the British Isles covering the last 4500years are assembled and re-evaluated with the aim of identifying centennial climate variability reflected by multi-proxy indicators. The proxies include bog oak populations, peatland surface wetness, flooding episodes from fluvial deposits, speleothem annual band width and oxygen isotopes, chironomids from lake sediments and sand and dune deposition. Most proxies reflect water balance rather than temper...

2010-01-01

408

Assessing variability of water quality in a groundwater-fed perennial lake of Kashmir Himalayas using linear geostatistics

British Library Electronic Table of Contents (United Kingdom)

This paper presents a study on Manasbal lake, which is one of the high altitude lakes in the Kashmir Valley, India. Eighteen water samples were analysed for major ions and trace elements to assess the variability of water quality of the lake for various purposes. Geostatistics, the theory of regionalized variables, was then used to enhance the dataset and estimate some missing spatial values. Results indicated that the concentration of major ions in the water samples in winter was higher than in summer. The scatter diagrams suggested the dominance of alkaline earths over the alkali elements. Three types of water were identified in the lake that are referred to as Ca?HCO3, Mg?HCO3 and hybrid types. The lake water was found to be controlled by rock?water interaction with carbonate lithology ...

2011-01-01

409

Advanced experimental design applied to damage tolerance of composite materials

A variable gene delivery carrier-biotinylated chitosan/polyethyleneimine

This paper focuses on a factorial-based design strategy. The approach provides an efficient and statistically reliable means for assessing the influence of multivariable effects. It is applied to the detection and evaluation of damage in impacted composite sandwich panels. The experimental results obtained from this test strategy are utilized to form an empirical response function. The resulting polynomial relates damage area to residual compression strength at values of independent variables for which testing did not occur. The response function also identifies nonlinear interaction effects of key variabes that cannot be easily ascertained by traditional single-variable test strategies. Independent variables evaluated include core thickness, number of face sheet plys and impact energy. The methodology presented allows the designer to predict with more confidence the damage tolerance of a composite material component, and ...

1991-01-01

410

A study on the pretreatment of a sugarcane bagasse sample with dilute sulfuric acid

A variable gene delivery system has been developed based on conjugating chitosan to biotin through a functionalized poly(ethylene glycol) (PEG) spacer, which can be used to further bind different molecules on the outer layer of a polymer/DNA complex by streptavidin (SA)-biotin linkage. In this study, TAT-conjugated SA was used as the model molecule to prove the conjugation function of the prepared complex. In addition, low-molecular-weight poly(ethyleneimine) (PEI) was added into the polymer/DNA complex to increase the transfection efficiency. The results of the luciferase assay show that the transfection efficiency of the prepared complex was significantly correlated with the amount of PEI and was further enhanced when TAT was conjugated to the complex by SA-biotin linkage. Considered to have negligible cytotoxic effects, the variable gene delivery complex prepared in this study would be of considerable potential as carriers for in vitro ...

2010-12-01

411

British Library Electronic Table of Contents (United Kingdom)

Experiments based on a 23 central composite full factorial design were carried out in 200-ml stainless-steel containers to study the pretreatment, with dilute sulfuric acid, of a sugarcane bagasse sample obtained from a local sugar?alcohol mill. The independent variables selected for study were temperature, varied from 112.5?C to 157.5?C, residence time, varied from 5.0 to 35.0 min, and sulfuric acid concentration, varied from 0.0% to 3.0% (w/v). Bagasse loading of 15% (w/w) was used in all experiments. Statistical analysis of the experimental results showed that all three independent variables significantly influenced the response variables, namely the bagasse solubilization, efficiency of xylose recovery in the hemicellulosic hydrolysate, efficiency of cellulose enzymatic saccharificatio...

2011-01-01

412

Search for a Methanopyrus-proximal last universal common ancestor based on comparative-genomic analysis

British Library Electronic Table of Contents (United Kingdom)

The origin of life is a long-standing mystery puzzling many people. This mystery possesses not only philosophical but also important biological significance. To unveil this mystery, the searches for the root of life, or the last universal common ancestor (LUCA), based on comparative-genomic analysis have been intensively performed on rRNAs, tRNAs and proteins sequences. The current search pointed to a Methanopyrus-proximal LUCA, which opens up the reconstruction of Lucan biology and helps to delineate the evolutionary pathways.

2011-01-01

413

Radiobiology

Possible processes of abiogenic synthesis of biologically important compounds on surface of small bodies in the Solar System

This text-book (electronic book - multi-media CD-ROM) constitutes a course-book - author's collection of lectures. It consists of 13 lectures in which the reader acquaints with the basis of radiobiology: Introduction to radiobiology; Physical fundamentals of radiobiology; Radiation of cells; Modification of radiation damage of cells; Reparation of radiation damage of cells; Radiation syndromes and their modification; Radiation injury; Radiation damage of tissues; Effect of radiation on embryo and fetus; Biological effects of incorporated radionuclides; Therapy of acute irradiation sickness; Delayed consequences of irradiation; Radiation oncology and radiotherapy. This course-book may be interesting for students, post-graduate students of chemistry, biology, physics, medicine as well as for teachers, scientific workers and physicians. (author)

414

Omic Approaches in Environmental Issues

A mixture of aminoacids was irradiated by a scattered proton beam, its energy varying from 4 to 6.6 MeV, by doses up to 5 x 10"1"1 proton/cm"2 for studying the potentiality of abiogenic synthesis of biologically important compounds in space. It was ascertained that increase in the radiation dose and reduction of proton energy involve increase in effectiveness both of destruction of the initial aminoacid (tryptophan, tyrosine, glycine) and synthesis of the relevant dipeptide. Essential influence of mineral substrate on abiogenic synthesis of natural nucleotides under the action of diverse energy sources was pointed out

2004-04-01

415

British Library Electronic Table of Contents (United Kingdom)

Biomonitoring requires the application of batteries of different biomarkers, as environmental contaminants induce multiple responses in organisms that are not necessarily correlated. Omic technologies were proposed as an alternative to conventional biomarkers since these techniques quantitatively monitor many biological molecules in a high-throughput manner and thus provide a general appraisal of biological responses altered by exposure to contaminants. As the studies using omic technologies increase, it is becoming clear that any single omic approach may not be sufficient to characterize the complexity of ecosystems. This work aims to provide a preliminary working scheme for the use of combined transcriptomic and proteomic methodologies in environmental biomonitoring. There are difficulti...

2011-01-01

416

Modelling heat and mass transfer in drying of biological materials. A simplified approach to materials with small dimensions

Migration of the long-lived radionuclides in soil-plant system under conditions of 30-km zone

A simplified approach has been proposed to model the drying of capillary-porous materials with small geometric parameters for practical purposes. Luikov`s theory of mass and heat transfer for capillary-porous bodies was applied to drying of biological materials and it was shown that the thermo diffusion effect can be neglected if the thermal gradient remains small during the whole period of drying. The resulting simplified equations can then be solved using available mathematical software. The simplified equations were applied to drying of wood and a peanut pod

1996-04-17

417

Influence of anaerobic microbial activity on biosorption of 2,4-dichlorophenol

Field experiments were conducted in the 30-km zone of Gomel's region of the Byelorussia to study factors aecting a biological radionuclide accessibility. A contamination density by radiocesium equaled 2,7-9,9 MBk/m"2, strontium 90 - 0,3-0,5 MBk/m"2 in 1991. A sowing of oats barley, lupin was carried out. It was shown that radionuclide accumulation by agricultural plants was determined basically by biological peculiarities of plants in greater degree than by the contamination density. It was shown that strontium 90 migration from the soil was more intensive than that of radiocesium. 8 tabs.

1992-05-15

418

Free radicals and their transformations in irradiated proteins

Biosorption is an important removal mechanism in treating hydrophobic toxic organics in biological reactors. Equilibrium sorption isotherms and sorption kinetics of 2,4-dichlorophenol on live and chemically inactive anaerobic granules were studied. A metabolic inhibitor was used to inactivate the biological activity of the biomass. Results showed that the difference in the biosorption of live and chemically inactive anaerobic granules is not significant. This would suggest that anaerobic biosorption is mainly a physical-chemical process and that metabolic-mediated diffusion in the process is negligible. 12 refs., 3 tabs., 7 figs.

1995-12-31

419

Environmental tobacco smoke and sudden infant death syndrome: a review

Experimental investigation data are systematized of free radical states and processes in irradiated proteins. The investigation is performed by the radiospectral methods. Results are discussed in detail of the study of free radicals electronic structure of amino acids, peptides and proteins formed by the action of ionizing radiation. The specificity is stressed of the study of monocrystalls of these compounds by the method of electronic paramagnetic resonance. The nature is also studied of primary centres formed under the effect of radiation on biologically important compounds and their subsequent reactions in solid and liquid solutions. Ion-radical states of different functional groups of the protein molecule are studied. Prospects of the study and the role of anion-radicals in biological processes are discusses.

420

British Library Electronic Table of Contents (United Kingdom)

Environmental tobacco smoke (ETS), containing the developmental neurotoxicant, nicotine, is a prevalent component of indoor air pollution. Despite a strong association with active maternal smoking and sudden infant death syndrome (SIDS), information on the risk of SIDS due to prenatal and postnatal ETS exposure is relatively inconsistent. This literature review begins with a discussion and critique of existing epidemiologic data pertaining to ETS and SIDS. It then explores the biologic plausibility of this association, with comparison of the known association between active maternal smoking and SIDS, by examining metabolic and placental transfer issues associated with nicotine, and the biologic responses and mechanisms that may follow exposure to nicotine. Evidence indicates that prenatal ...

2006-01-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

421

Conceptual design of a nuclear reactor facility for medical and biological purposes

Conceptual design of a nuclear reactor facility for medical and biological purposes

Optimal neutron energy for boron neutron capture therapy (BNCT) has been studied. Epithermal neutron is superior to thermal neutrons in treating deep-seated tumors. Design of the epithermal neutron column for BNCT has been performed by using a two-dimensional transport calculation code. Aluminum and heavy water are used as moderation materials. A thermal neutron column is also designed using heavy water as thermalization material. The configuration of the facility for treatment and research of BNCT and also for basic radio-biological studies of neutrons has been presented.

1981-09-01

422

In vitro H2AX phosphorylation and micronuclei induction in human fibroblasts across the Bragg curve of a 577MeV/nucleon Fe incident beam

Optimal neutron energy for boron neutron capture therapy (BNCT) has been studied. Epithermal neutron is superior to thermal neutrons in treating deep-seated tumors. Design of the epithermal neutron column for BNCT has been performed by using a two-dimensional transport calculation code. Aluminum and heavy water are used as moderation materials. A thermal neutron column is also designed using heavy water as thermalization material. The configuration of the facility for treatment and research of BNCT and also for basic radio-biological studies of neutrons has been presented. (author).

423

BMBF. The biotechnology 2000 project. Annual report 1994; BMBF. Programm Biotechnologie 2000. Jahresbericht 1994

The space environment consists of a varying field of radiation particles including high-energy ions, with spacecraft shielding material providing the only major protection to astronauts from harmful exposure. Unlike low-linear energy transfer (LET) {gamma} or X-rays, the presence of shielding does not always reduce the radiation risks for energetic charged particle exposure, since the dose delivered by the charged particle increases sharply as the particle approaches the end of its range, a position known as the Bragg peak. The Bragg curve does not necessarily represent the biological damage along the particle traversal, and the 'biological Bragg curve' is dependent on the energy and the type of the primary particle, and may vary for different biological endpoints. Here we used a unique irradiation geometry to measure the biological response across the Bragg curve in human fibroblasts ...

2006-10-15

424

Water Deficit and Spatial Pattern of Leaf Development. Variability in Responses Can Be Simulated Using a Simple Model of Leaf Development1

The `biotechnology 2000` project is supervised by the project sponsor `biology, energy, ecology` at Forschungszentrum Juelich on behalf of the Federal Ministry for Research and Technology. The project activities cover the development of techniques and methods, cell biology, gene structure and gene regulation, photosynthetic production processes, biological hydrogen production, synthetic biology, protein design, neurobiological research, biosystems, plant breeding, phytomedicine and plant protection, the biology of waste disposal methods, research into methods which replace animal experiments, biological safety research, technology risk assessment, and ethical aspects. A general survey introduces the promoted projects, and standardized data sheets briefly introduce the individual activities. The appendix gives the project indices, the indices of joint projects, a ...

1995-11-01

425

Variable domain I of nematode CLEs directs post-translational targeting of CLE peptides to the extracellular space

We analyzed the effect of short-term water deficits at different periods of sunflower (Helianthus annuus L.) leaf development on the spatial and temporal patterns of tissue expansion...Full Text Available

1999-02-01

426

Transposable elements are enriched within or in close proximity to xenobiotic-metabolizing cytochrome P450 genes

Effector proteins expressed in the esophageal gland cells of cyst nematodes are delivered into plant cells through a hollow, protrusible stylet. Although evidence indicates that effector proteins function...Full Text Available

2010-12-01

427

Transport of sorbing solutes in randomly heterogeneous formations: Spatial moments, macrodispersion, and parameter uncertainty

BackgroundTransposons, i.e. transposable elements (TEs), are the major internal spontaneous mutation agents for the variability of eukaryotic genomes. To address the general issue...Full Text Available

428

Time-Referenced Effects of an Internal vs. External Focus of Attention on Muscular Activity and Compensatory Variability

Expressions for the spatial moments and macrodispersion tensor for sorbing solutes in heterogeneous formations were presented using a probabilistic model of a fluid residence time coupled with the particle position analysis. The fluid residence time was defined as a fraction of the actual time during which the particle stayed in the mobile fluid phase of the aquifer. The fluid residence time is a random variable whose variability comes as a result of the non-equilibrium sorption properties. The sorbing solute was assumed to be governed with first-order linear kinetics. The closed-form expressions were based on the stationarity in the kinetic process and on the first-order approximation in the hydraulic conductivity field and in the fluid residence time. The non-equilibrium effects were presented as a function of the spatial variability in hydraulic conductivity and temporal variability in the fluid ...

1993-06-01

429

The Interaction between AID and CIB1 Is Nonessential for Antibody Gene Diversification by Gene Conversion or Class Switch Recombination

The paralysis-by-analysis phenomenon, i.e., attending to the execution of one's movement impairs performance, has gathered a lot of attention over recent years (see Wulf, 2007,...Full Text Available

430

Temporal Stability of Urinary and Plasma Biomarkers of Tobacco Smoke Exposure among Cigarette Smokers

Activation-induced deaminase (AID) initiates somatic hypermutation, gene conversion and class switch recombination by deaminating variable and switch region DNA cytidines to uridines. AID is predominantly...Full Text Available

431

Seasonal and Spatial Variability of Bacterial and Archaeal Assemblages in the Coastal Waters near Anvers Island, Antarctica

Intraindividual variability of measurements of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), nicotine, cotinine, and r-1,t-2,3,c-4-tetrahydroxy-1,2,3,4-tetrahydrophenanthrene...Full Text Available

2010-06-01

432

Relationship between mRNA secondary structure and sequence variability in Chloroplast genes: possible life history implications

A previous report of high levels of members of the domain Archaea in Antarctic coastal waters prompted us to investigate the ecology of Antarctic planktonic prokaryotes. rRNA hybridization...Full Text Available

1998-07-01

433

RESPONSE LATENCY AS AN INDEX OF RESPONSE STRENGTH DURING FUNCTIONAL ANALYSES OF PROBLEM BEHAVIOR

BackgroundSynonymous sites are freer to vary because of redundancy in genetic code. Messenger RNA secondary structure restricts this freedom, as revealed by previous findings in...Full Text Available

434

QOI10/477: The medCERTAIN Project: Rating and certification of Internet health information using medPICS

Dependent variables in research on problem behavior typically are based on measures of response repetition, but these measures may be problematic when behavior poses high risk or when its occurrence...Full Text Available

2011-01-01

435

Predictors of disability in a longitudinal sample of patients with rheumatoid arthritis.

IntroductionHealth information on the Internet undergoes no quality control at the stage of production, thus its quality is highly variable, making it difficult...Full Text Available

436

Practical Applications of the Bioinformatics Toolbox for Narrowing Quantitative Trait Loci

Information from the Health Assessment Questionnaire (HAQ) is used to identify which variables measured in 1981 successfully predict the severity of disease in 1989 and the eight year change in severity...Full Text Available

1992-05-01

437

Post traumatic stress symptoms and heart rate variability in Bihar flood survivors following yoga: a randomized controlled study

Dissecting the genes involved in complex traits can be confounded by multiple factors, including extensive epistatic interactions among genes, the involvement of epigenetic regulators, and the variable...Full Text Available

2008-12-01

438

OPTIMIZATION OF COMBINED SEWER OVERFLOW CONTROL SYSTEMS

BackgroundAn earlier study showed that a week of yoga practice was useful in stress management after a natural calamity. Due to heavy rain and a rift on the banks of the Kosi river,...Full Text Available

439

Non-Detection of Polarized, Scattered Light from the HD 189733b Hot Jupiter

The highly variable and intermittent pollutant concentrations and flowrates associated with wet-weather events in combined sewersheds necessitates the use of storage-treatment systems to control pollution.An optimized combined-sewer-overflow (CSO) control system requires a manage...

440

Monitoring the Simultaneous Presentation of Spatialized Speech Signals in a Virtual Acoustic Environment.

Using the POLISH instrument, I am unable to reproduce the large-amplitude polarimetric observations of Berdyugina et al. (2008) to the >99.99% confidence level. I observe no significant polarimetric variability in the HD 189733 system, and the upper limit to variability from the exoplanet is Delta_P < 7.9 x 10^(-5) with 99% confidence in the 400 nm to 675 nm wavelength range. Berdyugina et al. (2008) report polarized, scattered light from the atmosphere of the HD 189733b hot Jupiter with an amplitude of two parts in 10^4. Such a large amplitude is over an order of magnitude larger than expected given a geometric albedo similar to other hot Jupiters. However, my non-detection of polarimetric variability phase-locked to the orbital period of the exoplanet, and the lack of any significant variability, shows that the polarimetric modulation reported by Berdyugina et al. (2008) cannot be due to the ...

2009-01-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

441

Molecular Variability of Pseudallescheria boydii, a Neurotropic Opportunist

The effect of spatial auditory information on a listener's ability to detect, identify, and monitor multiple simultaneous speech signals was evaluated using virtual audio technology. Factorial combinations of three variables - the number of localized spee...

1998-01-01

442

Lymphoma depletion during CD20 immunotherapy in mice is mediated by macrophage Fc?RI, Fc?RIII, and Fc?RIV

The sequences of the internal transcribed spacer (ITS) ribosomal DNA (rDNA) domain data obtained by restriction fragment length polymorphism analysis with 18S rDNA and fingerprinting (M13) for clinical...Full Text Available

2000-09-01

443

Investigating the spatial variability in incidence of coronary heart disease in the Gazel cohort: the impact of area socioeconomic position and mediating role of risk factors

Despite the demonstrated clinical efficacy of CD20 monoclonal antibody (mAb) for lymphoma therapy, the in vivo mechanisms of tumor depletion remain controversial and variable. To identify the molecular...Full Text Available

2008-08-15

444

Industrial emissions cause extreme urban ozone diurnal variability

Study objectiveThe study aim was to improve our understanding of the relationships between contextual socioeconomic characteristics and coronary heart disease (CHD)...Full Text Available

2011-02-01

445

Incorporation of the International Spinal Cord Injury Data Set Elements into the National Institute of Neurological Disorders and Stroke (NINDS) Common Data Elements (CDEs)

Simulations with a regional chemical transport model show that anthropogenic emissions of volatile organic compounds and nitrogen oxides (NO_x = NO + NO₂) lead to a dramatic diurnal...Full Text Available

2004-04-27

446

Identification of genes and haplotypes that predict rheumatoid arthritis using random forests

ObjectiveTo develop consistent variable names and a common database structure for the data elements in the International Spinal Cord Injury (SCI) Data Sets.Full Text Available

2011-01-01

447

Human variability and susceptibility to trichloroethylene.

Random forest (RF) analysis of genetic data does not require specification of the mode of inheritance, and provides measures of variable importance that incorporate interaction effects. In this paper...Full Text Available

448

Hominin life history: reconstruction and evolution

Although humans vary in their response to chemicals, comprehensive measures of susceptibility have generally not been incorporated into human risk assessment. The U.S. EPA dose-response-based risk assessments...Full Text Available

2000-05-01

449

High genetic variability and low local diversity in a population of arbuscular mycorrhizal fungi

In this review we attempt to reconstruct the evolutionary history of hominin life history from extant and fossil evidence. We utilize demographic life history theory and distinguish life history variables,...Full Text Available

2008-04-01

450

High Speed Cylindrical Roller Bearing Development.

Arbuscular mycorrhizal fungi (AMF) are ecologically important root symbionts of most terrestrial plants. Ecological studies of AMF have concentrated on differences between species; largely assuming...Full Text Available

2004-02-24

451

Heats (enthalpies) of formation of coals and the thermodynamic evaluation of the coal formation process

High speed experimental tests provided data on six parametric cylindrical roller bearings. Four bearing variables were evaluated and the results were correlated with the analytical model developed under Naval Air Propulsion Center Contract N00140-76-C-038...

1980-01-01

452

British Library Electronic Table of Contents (United Kingdom)

An approach to the calculation of the quantity of heat consumed in the process of coal formation is presented. The variability of this parameter in a coalification series is analyzed using coals from the Kuznetsk and Tunguska Basins as an example.

2011-01-01

453

Hamiltonian BRST formalism for gauge-invariant systems with closed algebra

Glossitis of Military Workingn> Dogs in South Vietnam: History and Clinical Characteristics.

The systems for which the algebra of gauge transformations in the lagrangian formalism is closed, are considered. The hamiltonian BRST charge and the BRST-invariant hamiltonian are found explicitly. Their expansions in powers of the ghost variables contain, in general, an infinite number of terms. (orig.).

1991-11-01

454

Genome-wide linkage scan for contraction velocity characteristics of knee musculature in the Leuven Genes for Muscular Strength Study

Glossitis among U.S. military working dogs in South Vietnam was characterized by variable redness and loss of papillae on the anterodorsal third of the tongue; salivation, drooling, and inappetence were the principal clinical signs. Symptomatic treatment ...

1973-01-01

455

Genome size and wing parameters in passerine birds

The torque-velocity relationship is known to be affected by ageing, decreasing its protective role in the prevention of falls. Interindividual variability in this torque-velocity relationship is partly...Full Text Available

2008-09-01

456

Genetic architecture of voluntary exercise in an advanced intercross line of mice

Despite their status as the most speciose group of terrestrial vertebrates, birds exhibit the smallest and least variable genome sizes among tetrapods. It has been suggested that this is because powered...Full Text Available

2009-01-07

457

Feature Selection and Classification of MAQC-II Breast Cancer and Multiple Myeloma Microarray Gene Expression Data

Exercise is essential for health, yet the amount, duration, and intensity that individuals engage in are strikingly variable, even under prescription. Our focus was to identify the locations and effects...Full Text Available

2010-07-01

458

Experimental evaluation of angularly-variable fiber geometry for targeting depth-resolved reflectance from layered epithelial tissue phantoms

Microarray data has a high dimension of variables but available datasets usually have only a small number of samples, thereby making the study of such datasets interesting and challenging. In the task...Full Text Available

459

Effect of Wastewater Treatment Plant Effluent on Microbial Function and Community Structure in the Sediment of a Freshwater Stream with Variable Seasonal Flow?

The aim of the present study focuses on experimentally demonstrating the efficacy of using angularly-variable fiber geometry to achieve the desired tissue-layer selection and probing depths with the further objective of enhancing the sensitivity and specificity of spectral diagnosis in stratified architectures that resemble human cervical epithelia. The morphological and biochemical features of epithelial tissue vary in accordance with tissue depths; consequently, the accuracy of spectroscopic diagnosis of epithelial dysplasia may be enhanced by probing the optical properties of this tissue. When correlated to cellular dysplasia, layer-specific changes in tissue optical properties may be deciphered by reflectance spectroscopy coupled with angularly-variable fiber geometry. This study addresses the utility of using such angularly-variable fiber geometry for resolving spatially-specific spectral signatures of tissue ...

2007-03-01

460

EFFECT OF THE DIGENEAN PARASITE PROTEROMETRA MACROSTOMA ON HOST MORPHOLOGY IN THE FRESHWATER SNAIL ELIMIA LIVESCENS

We investigated the effects of wastewater treatment plant (WWTP) discharge on the ecology of bacterial communities in the sediment of a small, low-gradient stream in South Australia. The quantification...Full Text Available

2008-05-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

461

Do the Obese Have Lower Body Temperatures? A New Look at a Forgotten Variable in Energy Balance

... 1984; Martin-Mora et al., 1995), and parasitism (Rothschild and Rothschild, 1939; Pesigan et al., 1958; Moose, 1963; Pan, ... effects of digeneans are variable; they may enhance (Rothschild and Rothschild...

462

Dimensionless energy confinement scaling in W7-AS

Understanding the pathogenesis of obesity is now more important than ever, given the remarkable world-wide epidemic. This paper explores the potential role of core temperature in energy balance, and...Full Text Available

2009-01-01

463

Detrended Fluctuation Analysis of Intracranial Pressure Predicts Outcome Following Traumatic Brain Injury

Energy confinement in W7-AS has been analyzed in terms of dimensionally exact form free functions employing Bayesian probability theory. The confinement function was set up as a linear combination of dimensionally exact power law terms as already proposed very early by Connor and Taylor. Generation of this expansion basis is dictated by the basic plasma model which one assumes. Based upon data accumulated in W7-AS, which contains the energy content for a wide variety of variable settings, predictions for single variable scans are made. The scaling functions for density and power scans, respectively, are in quantitative agreement with data collected in W7-AS. The result of a single variable scan is therefore already hidden in the data obtained for arbitrary variable choices and can be extracted from the latter by a proper data analysis. Furthermore, the optimal model for the description of the global ...

1999-12-01

464

Determinants of output in group and solo medical practice.

Detrended fluctuation analysis (DFA) is a recently developed technique suitable for describing scaling behavior of variability in physiological signals. The purpose of this study is to explore...Full Text Available

2008-11-01

465

Determinants of health insurance ownership among South African women

Certain structural and environmental factors other than technical combination of resources and firm size are hypothesized to affect medical practice output. Four groups of variables related to physician...Full Text Available

1976-01-01

466

Climate models and scenarios

BackgroundStudies conducted in developed countries using economic models show that individual- and household- level variables are important determinants of health insurance ownership....Full Text Available

467

Cangrelor increases the magnitude of platelet inhibition and reduces interindividual variability in clopidogrel-pretreated subjects

In recent years the modelling of interannual climate variability has been studied, the atmospheric energy and water cycles, and climate simulations with the ECHAM3 model. In addition, the climate simulations of several models have been compared with special emphasis in the area of northern Europe

1996-12-31

468

Calibration of the solar UV radiometers in Finland

BackgroundInadequate platelet inhibition despite aspirin and clopidogrel therapy during and after a percutaneous coronary intervention is associated with an impaired clinical outcome....Full Text Available

2009-05-01

469

CYP1B1 mutations in Spanish patients with primary congenital glaucoma: phenotypic and functional variability

In this report, the main emphasis is given to (1) the problems associated with the basic calibration of the spectroradiometer and (2) the year-to-year variability of the calibrations of the solar UV network radiometers. Also, the results from intercomparisons of the Brewer and OL 742 spectroradiometers are included

1996-12-31

470

Boundary value problem for an elliptic equation with rapidly oscillating coefficients in a rectangle

PurposeTo analyze the contributions of cytochrome P4501B1 (CYP1B1) mutations to primary congenital glaucoma (PCG) in Spanish patients.MethodsWe...Full Text Available

471

British Library Electronic Table of Contents (United Kingdom)

An elliptic equation in a rectangle with coefficients depending on a fast variable and with its period being a small parameter is considered. An asymptotic expansion of the solution up to an arbitrary degree of the small parameter is constructed and substantiated by applying the two-scale expansion method.

2011-01-01

472

Average uncertainty as a determinant of observing behavior1

Automatic stenosis detection and quantification in renal arteriography.

After discrimination training on a multiple variable-interval extinction schedule of food reinforcement, pigeons were placed on the uncued or mixed version of the same schedule and allowed to make...Full Text Available

1974-09-01

473

Assessing spatio-temporal variability of risk surfaces using residential history data in a case control study of breast cancer

Visual assessment of the degree of renal artery stenosis on renal arteriography has a large inter- and intraobserver variability. This degree is usually estimated by the ratio between the most narrowed...Full Text Available

1997-01-01

474

Aspirin and Clopidogrel Response Variability

BackgroundMost analyses of spatial clustering of disease have been based on either residence at the time of diagnosis or current residence. An underlying assumption in these analyses...Full Text Available

475

Analytical study on analysis methods of several random variables for seismic nonlinear responses of reactor buildings

Antiplatelet resistance has been proposed as a possible mechanism to explain recurrent cardiovascular events in patients who have coronary artery disease and who are undergoing dual antiplatelet therapy....Full Text Available

2008-01-01

476

Absolute CD4+ T-Lymphocyte Count as a Surrogate Marker of Pediatric HIV Disease Progression

In the case wherein nonlinear seismic response analyses are carried out, the response values vary due to the variations in materials and modeling. In this paper, nonlinear analyses of several random variables are carried out using: i. a conventional method; ii. a two-point estimation method (i. and ii. are simplified methods); and iii. Monte Carlo simulation (detailed method) to examine the variability of the response in the excessive nonlinear range for seismic responses of shear walls. The analyses are performed to a PWR-3 loop type reactor building which is one of the most typical reactor buildings in Japan. The variations are considered in specified compressive strength of concrete, concrete damping factor, shear wave velocity of soil and shapes of shear stress-strain relation curves of shear walls. As the results by the two simplified methods closely matched the Monte Carlo simulation results, the appropriateness for applying the ...

1993-08-15

477

A new evolutionary scenario for the Mycobacterium tuberculosis complex

BackgroundTraditionally in pediatric HIV, the CD4+ T-lymphocyte percent is used in monitoring disease progression due to the variability in absolute CD4+ T-lymphocyte...Full Text Available

2008-07-01

478

A new VCAN/versican splice acceptor site mutation in a French Wagner family associated with vascular and inflammatory ocular features

The distribution of 20 variable regions resulting from insertion-deletion events in the genomes of the tubercle bacilli has been evaluated in a total of 100 strains of Mycobacterium tuberculosis,...Full Text Available

2002-03-19

479

A Latent Variable Approach for Meta-Analysis of Gene Expression Data from Multiple Microarray Experiments

PurposeTo detail the highly variable ocular phenotypes of a French family affected with an autosomal dominantly inherited vitreoretinopathy and to identify the disease gene.MethodsSixteen...Full Text Available

480

A Computational Framework Discovers New Copy Number Variants with Functional Importance

BackgroundWith the explosion in data generated using microarray technology by different investigators working on similar experiments, it is of interest to combine results across...Full Text Available

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481

Variable-dispersion electron spectrometer for the SCA/FEL

Structural variants which cause changes in copy numbers constitute an important component of genomic variability. They account for 0.7% of genomic differences in two individual genomes, of which...Full Text Available

482

United States Air Force Academy (USAFA) Vertical Axis Wind Turbine. Final report May 77-Sep 80

A variable-dispersion electron spectrometer is being installed for use by the Stanford Superconducting Accelerator in conjunction with its Free Electron Laser program. The system has been designed to operate with electron beam energies from 20 MeV to 200 MeV, with a maximum energy resolution of 0.01% FWHM. The maximum energy acceptance is approximately #+-# 5%, as determined by the bending magnet aperture. Resolution is controlled by adjusting the focal conditions at the entrance to a 90 degree bending magnet, while the dispersion is controlled by changing the magnitude and polarity of the field in a quadrupole magnet which immediately follows the bending magnet. 4 refs., 5 figs.

1989-06-01

483

The effects of aircraft engine pollutant emission measurement variability on engine certification policy

This report describes the design, fabrication, installation and testing of a small variable-speed vertical axis wind turbine (VAWT). This VAWT is unique in its installation using hand tools only; unconventional and simple support system; and variable speed operation under microprocessor control. Initial testing confirmed that the turbine can be controlled by commanded alternator field modulation. Further studies will be directed toward determination of an optimum control algorithm.

1980-09-01

484

Separation of variables for the quantum SL(2,R) spin chain

Divergence between aircraft engine emission regulations proposed by EPA and ICAO is discussed. Every engine, upon entering service, requires a certificate as to its compliance with emission standards. It is shown that despite the large variability in the measurements, it is possible to devise a certification procedure requiring the testing of one engine only. Statistical modeling of such a test at the 5% significance level is described. Values of the parameter standard deviation/mean recommended as certification standards for various pollutants are given. Features of a rational certification scheme to be formulated are outlined.

1978-10-01

485

Product identification in industrial batch fermentation using a variable forgetting factor

We construct representation of the Separated Variables (SoV) for the quantum SL(2,R) Heisenberg closed spin chain and obtain the integral representation for the eigenfunctions of the model. We calculate explicitly the Sklyanin measure defining the scalar product in the SoV representation and demonstrate that the language of Feynman diagrams is extremely useful in establishing various properties of the model. The kernel of the unitary transformation to the SoV representation is described by the same "pyramid diagram" as appeared before in the SoV representation for the SL(2,C) spin magnet. We argue that this kernel is given by the product of the Baxter Q-operators projected onto a special reference state.

2003-01-01

486

British Library Electronic Table of Contents (United Kingdom)

For reliable operation and the optimization of production, industrial fermentation processes require appropriate tools for monitoring the process in real time. This work presents the structure and operation of a soft sensor for the on-line monitoring of biomass and product concentration during salinomycin and bacitracin fermentation in an industrial, 80-m^3 batch reactor; moreover it provides a tool for evaluation of batch production verified in industrial application. The process estimation algorithm consists of decoupled growth and product models, which ensures an unbiased convergence of the estimator and the robustness of the model. The production of secondary metabolites is described with a non-structured model upgraded with a variable forgetting factor that demonstrated a successful e...

2011-01-01

487

Method and system for controlling the idle speed of an internal combustion engine at variable ignition timing

Less BOP running with variable bore rams

The idle speed of an internal combustion engine is controlled in response to a variable ignition timing control signal from a microcomputer. The microcomputer derives this control signal as a function of the magnitude of engine speed variation which occurs during engine idle periods to cause the ignition timing to vary quickly in response to a transitory engine load variation. An auxiliary air delivery system may be advantageously incorporated in the idle speed control system to cooperate with the ignition timing control in response to the engine speed variation.

1984-05-08

488

Inclusive photoproduction of D{sup *{+-}} mesons at next-to-leading order in the general-mass variable-flavor-number scheme

The marine ram-type blowout preventer deployed from an offshore drilling rig has one serious disadvantage, its inaccessibility. A development to promote reliability of the subsea ram-type preventer and reduce the excess running and pulling to charge out rams, is the variable bare ram (VBR). Unlike the standard ram, the VBR has the ability to pack off a range of pipe sizes. Interest in VBR's has been revived and research and development in this equipment goes on at each of three manufacturer's facilities in Houston.

1984-04-01

489

Evolution of the white dwarf mass and spin in cataclysmic variables

We discuss the inclusive production of D{sup *{+-}} mesons in {gamma}p collisions at DESY HERA, based on a calculation at next-to-leading order in the general-mass variable-flavor-number scheme. In this approach, MS subtraction is applied in such a way that large logarithmic corrections are resummed in universal parton distribution and fragmentation functions and finite mass terms are taken into account. We present detailed numerical results for a comparison with data obtained at HERA and discuss various sources of theoretical uncertainties. (orig.)

2009-02-15

490

Energy productivity in the industrial sector: an econometric analysis

We consider the spin-up of the white dwarf in non-magnetic cataclysmic variables (CVs) during secular evolution. If this is unresisted, CVs are quenched as boundary-layer emitters once the binary period has decreased by #approx# 1 hr. Angular momentum loss in nova explosions may, however, prevent the star reaching breakup. If the explosions remove (1 + #epsilon#) x the mass accreted between outbursts, values 0.5 < #approx# #epsilon# < #approx# 1 allow CVs to be modest boundary-layer emitters for most of their lifetimes. Spectral effects will limit their detection as soft X-ray sources. (author).

491

Effects of variable hardness, ph, alkalinity, suspended clay, and humics on the chemical speciation and aquatic toxicity of copper

Energy productivity and energy intensity within the industrial sector of the economy are examined. Results suggest that relative prices and other economic factors can explain much of the variation in both energy productivity and energy intensity for manufacturing and mining and for the industrial sector as a whole. Cyclical factors, seasonal factors and trend variables are also useful in explaining variation in these data, both for annual and monthly time series. Of the variables examined, it appears that the relative price of energy is a highly significant factor in accounting for the difference between actual industrial energy intensity and that which might have been expected had pre-1973 trends continued.

1983-01-01

492

Coherent state quantum key distribution with multi letter phase-shift keying

The effects of variable hardness, pH, alkalinity, humics, and suspended clay on the chemical speciation of copper and its toxicity to fathead minnow larvae in Lake Superior water were investigated. Two proposed methods (toxicity factors and chemical speciation) for predicting LC50 values in specific natural waters from laboratory toxicity data and the average site specific values of general water quality parameters were evaluated. The accuracy of the cupric ion-selective electrode in determining CU/sup +2/ activities in ambient and chemically altered Lake Superior water was also determined.

1986-03-01

493

Assessment of primary production and optical variability in shelf and slope waters near Cape Hatteras, North Carolina. Final project report

We present a protocol for quantum key distribution using discrete modulation of coherent states of light. Information is encoded in the variable phase of coherent states which can be chosen from a regular discrete set ranging from binary to continuous modulation similar to phase-shift keying in classical communication. Information is decoded by simultaneous homodyne measurement of both quadratures and requires no active choice of basis. The protocol utilizes either direct or reverse reconciliation both with and without postselection. We analyze the security of the protocol and show how to enhance it by the optimal choice of all variable parameters of the quantum signal.

2010-05-01

494

A finite-dimensional fermionic TQFT

In this project we determined primary production and optical variability in the shelf and slope waters off of Cape Hatteras, N.C. These processes were addressed in conjunction with other Ocean Margins Program investigators, during the Spring Transition period and during Summer. We found that there were significant differences in measured parameters between Spring and Summer, enabling us to develop seasonally specific carbon production and ecosystem models as well as seasonal and regional algorithm improvements for use in remote sensing applications.

2001-02-12

495

A comment on: ''The solution to the forward-bias puzzle''

A fermionic - based on Grassmann--Berezin calculus of anticommuting variables - topological quantum field theory (TQFT) is considered, mainly in three dimensions. It is defined for piecewise-linear manifolds and, for a given triangulation, deals only with a finite number of variables. Despite its simple nature, it can distiguish between lens spaces L(7,1) and L(7,2). And despite its origin from a kind of Reidemeister torsion, it does this without using nontrivial representations of the fundamental group. Also, symbolic calculations are presented giving strong evidence of existence of similar theory in four dimensions.

2011-01-01

496

British Library Electronic Table of Contents (United Kingdom)

Pippenger (2011) recently proposed a solution to the longstanding forward-bias puzzle. He argues that the puzzling estimates obtained using the standard equation for the efficient markets hypothesis are due to omitted variable bias. He identifies the missing variables as the future change in the forward exchange rate and the future interest differential. When these are added to the standard equation, he finds a one-to-one relationship between the future change in the spot rate and the forward premium. However, we argue that his equation can only test covered interest parity and offers no insight into the forward-bias puzzle.

2011-01-01

497

Stochastic analysis of contaminant transport: One-dimensional non-reactive and reactive cases

Upflow anaerobic sludge reactors for the treatment of combined industrial effluent in subtropical conditions: a comparison between UASB and UASF reactors

A reliability approach for probabilistic modeling of one-dimensional non-reactive and reactive transport in porous media provides two important quantitative results: (1) an estimate of the probability that dimensionless concentration equals or exceeds some specified level and, (2) the sensitivity of the probabilistic outcome to likely changes in each uncertain variable. The reliability approach is particularly attractive because it can incorporate various marginal probability density functions (PDF) for any of the uncertain variables. In this work uncertain variables include: groundwater flow velocity, diffusion coefficient, dispersivity, distribution coefficient, porosity and bulk density. The primary objective is to examine how the probabilistic outcome is influenced by choice of marginal PDF, correlation and magnitude of uncertainty for the variables. Because little information exists concerning the ...

1990-12-03

498

Biological responses to the chemical recovery of acidified fresh waters in the UK

The performance of anaerobic biological process is heavily process conditions dependent. In this study, an attempt has been made to investigate the influence of process conditions like temperature, sludge age and hydraulic retention time (HRT) on the efficiency of an upflow anaerobic sludge blanket (UASB) reactor and upflow anaerobic sludge filter (UASF) to treat combined industrial wastewater. Reactors were operated at easing ambient temperatures (38, 30, 20 and 14 deg. C) and correspondingly increasing sludge ages (60, 90, 120 and 150 days). At temperature 38 deg. C and sludge age of 60 days, UASF showed better performance than VASE reactor. This mainly due to the enhanced filtration through well-graded sand filter and fairly good biological activity in UASF. At this stage, lack of sludge granulation in VASE reactor resulted in poor biological activity; hence, relatively poor performance. At temperatures 30 and 20 deg. C ...

2004-06-07

499

Biological conversion of synthesis gas. Limiting conditions/scale-up

We report biological changes at several UK Acid Waters Monitoring Network lakes and streams that are spatially consistent with the recovery of water chemistry induced by reductions in acid deposition. These include trends toward more acid-sensitive epilithic diatom and macroinvertebrate assemblages, an increasing proportional abundance of macroinvertebrate predators, an increasing occurrence of acid-sensitive aquatic macrophyte species, and the recent appearance of juvenile (<1 year old) brown trout in some of the more acidic flowing waters. Changes are often shown to be directly linked to annual variations in acidity. Although indicative of biological improvement in response to improving water chemistry, 'recovery' in most cases is modest and very gradual. While specific ecological recovery endpoints are uncertain, it is likely that physical and biotic interactions are influencing the rate of recovery of certain groups of organisms at ...

2005-09-01

500