vaccine allocation strategies: Topics by WorldWideScience.org

International Science & Technology Center (ISTC)

Israel has faced the challenge presented by epidemic poliomyelitis by using different immunization strategies. In the 1950s, inactivated poliovirus vaccine (IPV) helped to reduce the total burden of...Full Text Available

1994-01-01

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Influenza Vaccines

Development of the Culture Influenza Vaccine

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Strategies for the production of genetically identical monkeys by embryo splitting

Emulsified Nanoparticles Containing Inactivated Influenza Virus and CpG Oligodeoxynucleotides Critically Influences the Host Immune Responses in Mice

Genetically identical rhesus monkeys would have tremendous utility as models for the study of human disease and would be particularly valuable for vaccine trials and tissue transplantation studies where...Full Text Available

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BackgroundAntigen sparing and cross-protective immunity are regarded as crucial in pandemic influenza vaccine development. Both targets can be achieved by adjuvantation strategy...Full Text Available

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(Form for)

IDEAS: Maritime Economics and Logistics, Palgrave Macmillan Journals

Date: Cost: Allocation:

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Malnutrition, Gut-Microbial Interactions and Mucosal Immunity to Vaccines, 07 Nov 2011 - 11 Nov 2011, Le Meridien New Delhi, New Delhi, India - SciDe

... (restricted)] 319-341 The value of container terminal investment to ocean carrier strategy by Thomas Pawlik & Lars Stemmler & Alfred J Baird ... (restricted)] 142-173 Prediction of arrival times and human resources allocation for container terminal by Gianfranco Fancello & Claudia Pani & Marco Pisano ... (restricted)] 347-369 Analysis of berth allocation and inspection operations in a container terminal by Yongpei Guan & Kang-hung Yang [Downloadable! (... (restricted)] 237-262 Container terminal concessions: A game theory application to the case of the ports of Pakistan by Naima Saeed & Odd ...

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Targeting vaccines to dendritic cells

... A better understanding of the links between nutrients, the gut microbiome and the intestinal immune system is likely to pave the way to the development of innovative approaches that target activation of specific immunological pathways for promoting the hostrsquo;s gut defense. Such knowledge should positively impact on the development of vaccine formulations and intervention strategies for improved control of enteric infections in developing countries. Registration fees # The Registration Fee is $715.00 on and before September 7, 2011. # After September 7, 2011, the ...

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Review on the immunology of European sea bass Dicentrarchus labrax

Udgivelsesdato: 2002-Mar

2002-01-01

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British Library Electronic Table of Contents (United Kingdom)

European sea bass (Dicentrarchus labrax L.) is a marine species of great economic importance, particularly in Mediterranean aquaculture. However, numerous pathogenic viruses, bacteria, fungi and parasites affect the species, causing various infectious diseases and thereby leading to the most heavy losses in aquaculture production of sea bass. In this respect, knowledge on molecular and genetic mechanisms of resistance to pathogens and specific features of immune response against various infectious agents should greatly benefit the development of effective vaccines and proper vaccination strategies in marker-assisted selection of fish resistant to a range of infections. To date, genetic knowledge on sea bass immune regulatory genes responsible for resistance to pathogens is relatively poor ...

2007-01-01

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Cochrane Review: Polysaccharide vaccines for preventing serogroup A meningococcal meningitis

British Library Electronic Table of Contents (United Kingdom)

AbstractBackground Randomised controlled trials (RCTs) in the 1970s and early 1980s showed the polysaccharide serogroup A vaccine (SgAV) prevented serogroup A meningococcal meningitis (SGAMM). Subsequent non-RCTs suggested significant variations in the age-specific duration of protection among children. Objectives To determine the protective effect, duration of protection, age-specific effects and the effect of booster doses in children of the SgAV against SGAMM. Search strategy We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2010, issue 2) which contains the Acute Respiratory Infections Group's Specialised Register, MEDLINE (January 1950 to May Week 3, 2010) and EMBASE (January 1974 to May 2010). Selection criteria We included RCTs. Non-RCTs ...

2011-01-01

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Design and Analysis of Vaccine Studies Questions of Analysis, Geometry & Algorithmics

Efficient mitigation strategies for epidemics in rural regions

Design and Analysis of Vaccine Studies

2010-01-01

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Vaccination against hepatitis A virus in French hemophilic children.

Containing an epidemic at its origin is the most desirable mitigation. Epidemics have often originated in rural areas, with rural communities among the first affected. Disease dynamics in rural regions have received limited attention, and results of general studies cannot be directly applied since population densities and human mobility factors are very different in rural regions from those in cities. We create a network model of a rural community in Kansas, USA, by collecting data on the contact patterns and computing rates of contact among a sampled population. We model the impact of different mitigation strategies detecting closely connected groups of people and frequently visited locations. Within those groups and locations, we compare the effectiveness of random and targeted vaccinations using a Susceptible-Exposed-Infected-Recovered compartmental model on the contact network. Our simulations show that the targeted ...

2010-01-01

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Influenza

Medline Plus

... a flu shot There is a new nasal spray version of the vaccine, and it contains weakened ... the LAIV (Live Attenuated Influenza Vaccine). The nasal-spray flu vaccine contains three different live but weakened ...

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CDC - Seasonal Influenza (Flu) - Q & A: 2007-08 Influenza (Flu...

PMID:7483502

1995-01-01

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CDC - Seasonal Influenza (Flu) - Q & A: 2006-07 Influenza (Flu...

home when you are sick helps everyone you care about Questions & Answers Flu Vaccine: Q&A Vaccine Dosage & Administration Vaccine Supply for 2011-12 Season Vaccine Supply and...

2011-10-15

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CDC - Seasonal Influenza (Flu) - Q & A about the 2010-2011 Flu...

home when you are sick helps everyone you care about Questions & Answers Flu Vaccine: Q&A Vaccine Dosage & Administration Vaccine Supply for 2011-12 Season Vaccine Supply and...

2011-10-15

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Response to measles-mumps-rubella vaccine in children on dialysis.

home when you are sick helps everyone you care about Questions & Answers Flu Vaccine: Q&A Vaccine Dosage & Administration Vaccine Supply for 2011-12 Season Vaccine Supply and...

2011-10-15

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Hepatitis B immunization coverage and risk behaviour among Danish travellers Are immunization strategies based on single journey itineraries rational?

Ten children receiving maintenance dialysis were immunized with the standard dose of measles-mumps-rubella vaccine between 15 and 33 months of age. Immune responses to vaccination were determined using commercially available enzyme-linked immunosorbent assays for measles, mumps, and rubella viruses. Eight children responded to measles vaccine, 5 to mumps vaccine, 8 to rubella vaccine, and only 3 children to all three vaccines, compared with a seroconversion rate of over 90% to all three vaccines in healthy children (P less than 0.0001). We contend that the relatively poor immunocompetence of our dialysis patients explains their less than optimal vaccine response and suggest that children vaccinated while undergoing dialysis be tested to confirm serological evidence of immunity. PMID:1571219

1992-03-01

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Advances in molecular biology: impact on rotavirus vaccine development.

OBJECTIVES: The authors examine the rationale and efficacy of pre-travel hepatitis B immunization strategies based on itinerary and presumed on-travel risk behaviour. METHODS: A large survey among 26,640 Danes survey provided data on journey lengths and destinations, immunization coverage, risk behaviour and knowledge. RESULTS: The estimated cumulative lifetime stay in endemic areas outside Europe is 4.3 months. The majority of risk situations are involuntary and unforeseeable. The majority of risk situations occur on short-term journeys. 5% nonimmune and 5% short-term travellers experienced at least one risk situation such as injections/operations/tattoos on their journey. The level of knowledge of hepatitis A and B is low. CONCLUSIONS: The rationale and efficacy of current immunization strategies are challenged. Based on the results presented here and the availability of vaccines with long-lasting coverage, the authors ...

2009-01-01

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Variation in male reproductive traits among three bitterling fishes (Acheilognathinae: Cyprinidae) in relation to the mating system

The first candidate rotavirus vaccine was a live attenuated oral vaccine made by the classical empirical method of serial passage of virus in tissue culture cells. Current tetravalent vaccine candidates that are in the final stages of efficacy testing in the United States were made by genetic reassortment. This article briefly highlights how advances in the basic understanding of the molecular biology of rotaviruses have facilitated vaccine development. New approaches for second-generation vaccines and improvements in vaccine efficacy based on further exploitation of the tools and knowledge of rotavirus molecular biology and pathogenesis are discussed. PMID:8752289

1996-09-01

23

British Library Electronic Table of Contents (United Kingdom)

Male traits that correlate with fertilization success include testis size and structure, ejaculate size, ejaculation frequency, and sperm motility. Two hypotheses potentially explain interspecific differences in these traits: sperm competition and sperm limitation. We examined variation in six traits associated with fertilization success in three closely-related species of bitterling fish; the European bitterling (Rhodeus amarus), the Chinese rose bitterling (Rhodeus ocellatus), and the Chinese bitterling (Rhodeus sinensis). Interspecific differences indicated that the three study species have evolved different sperm allocation strategies. Rhodeus amarus displayed the most developed reproductive apparatus with a number of traits associated with both high levels of sperm production and fert...

2011-01-01

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Measurements of environmental policy for air pollution abatement. Umweltpolitische Massnahmen zur Luftreinhaltung; Kosten-Nutzen-Analyse

Delay-Limited Cooperative Communication with Reliability Constraints in Wireless Networks

The first part of the study goes into the determination of efficient strategies for the reduction of air pollutants. The developed method is not only derived theoretically but is tested with the concrete example of emissions sources of a German state. The second part goes into the question what the government can do in order to attain that air pollution abatement measures recognized as being efficient will be put into practice. As market economy mechanisms have advantages over central state planning in the allocation of economic resources the question arises if not also for environmental protection market economy tools may contribute to an improvement of the efficiency of air pollution abatement. Therefore the suitability of different tools of environmental policy for the realization of efficient air pollution abatement is investigated and evaluated. This is again not done abstractly but with existing emission sources. (orig./HSCH). 32 figs., ...

1993-01-01

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Water demand management in areas of ground water over-exploitation

We investigate optimal resource allocation for delay-limited cooperative communication in time varying wireless networks. Motivated by real-time applications that have stringent delay constraints, we develop a dynamic cooperation strategy that makes optimal use of network resources to achieve a target outage probability (reliability) for each user subject to average power constraints. Using the technique of Lyapunov optimization, we first present a general framework to solve this problem and then derive quasi-closed form solutions for several cooperative protocols proposed in the literature. Unlike earlier works, our scheme does not require prior knowledge of the statistical description of the packet arrival, channel state and node mobility processes and can be implemented in an online fashion.

2009-01-01

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Male mammals respond to a risk of sperm competition conveyed by odours of conspecific males

SummaryIntended Outputs: Identification and evaluation, using participatory approaches, of demand management options:*Technical*Allocative and market based*Impact on target beneficiariesSupporting measures required when introducing water demand management options above:*Extension services & training*Water licences/rights*Institutional changes*Legal measures and regulation*Education*Support in diversifying to less water demanding activities*S [continued...]ObjectivesIdentification of the most appropriate demand management strategies for ground water abstraction, where aquifiers are being over-exploited, ensuring sustainable livelihoods of the vulnerable and poor are safeguarded. Poverty reduction strategies for areas where groundwater is being over-exploited.DescriptionProject Background: Groundwater is the principal source of both irrigation and domestic water supplies in many arid and semi-arid countries. However, many ...

2006-01-15

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Safety and immunogenicity of a vaccine bait containing ERA strain of attenuated rabies virus.

Sperm competition occurs when a female copulates with two or more males and the sperm of those males compete within the female's reproductive tract to fertilize her eggs. The frequent occurrence of sperm competition has forced males of many species to develop different strategies to overcome the sperm of competing males. A prevalent strategy is for males to increase their sperm investment (total number of sperm allocated by a male to a particular female) after detecting a risk of sperm competition. It has been shown that the proportion of sperm that one male contributes to the sperm pool of a female is correlated with the proportion of offspring sired by that male. Therefore, by increasing his sperm investment a male may bias a potential sperm competition in his favour. Here we show that male meadow voles, Microtus pennsylvanicus, increase their sperm investment when they mate in the presence of another male's odours. Such ...

2004-09-01

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Population-based prevention of influenza in Dutch general practice.

Ninety percent of foxes fed commercial ERA vaccine in a specially designed bait developed rabies serum neutralizing antibodies. The vaccine bait did not cause clinical signs of rabies when consumed...Full Text Available

1987-10-01

29

Novel Approach for Differential Diagnosis of HIV Infections in the Face of Vaccine-Generated Antibodies

BACKGROUND: Although the effectiveness of influenza vaccination in high-risk groups has been proven, vaccine coverage continues to be less than 50% in The Netherlands. To improve vaccination rates,...Full Text Available

1997-06-01

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Contrasting Population Structures of the Genes Encoding Ten Leading Vaccine-Candidate Antigens of the Human Malaria Parasite, Plasmodium falciparum

SummaryBecause increasing numbers of HIV vaccine candidates are being tested globally, it is essential to differentiate vaccine-from virus-induced antibodies. Most of the currently...Full Text Available

2006-11-01

31

A semi-qualitative study of attitudes to vaccinating adolescents against human papillomavirus without parental consent

The extensive diversity of Plasmodium falciparum antigens is a major obstacle to a broadly effective malaria vaccine but population genetics has rarely been used to guide vaccine design....Full Text Available

32

Isolation and Identification of Mycoplasmas

BackgroundThe first vaccine to prevent human papillomavirus (HPV) and cervical cancer has been licensed, and in future, vaccination may be routinely offered to 10–14 year...Full Text Available

33

International Science & Technology Center (ISTC)

Isolation and Identification of Mycoplasmas, Development of Reliable Antigen for Mycoplasmas Detection and Oil-Based Vaccines

34

LHC Magnet Tests Operational Techniques and Empowerment for Successful Completion

Energy and agriculture in the Haitian economy: A computable general equilibrium model

The LHC magnet tests operation team developed various innovative techniques, particularly since early 2004, to complete the superconductor magnet tests by Feb. 2007. Overall and cryogenic priority handling, rapid on-bench thermal cycling, rule-based goodness evaluation on round-the-clock basis, multiple, mashed web systems are some of these techniques applied with rigour for successful tests completion in time. This paper highlights these operation empowerment tools which had a pivotal role for success. A priority handling method was put in place to enable maximum throughput from twelve test benches, having many different constraints. For the cryogenics infrastructure, it implied judicious allocation of limited resources to the benches. Rapid On-Bench Thermal Cycle was a key strategy to accelerate magnets tests throughput, saving time and simplifying logistics. First level magnet appraisal was developed for 24 hr decision making so as to ...

2007-01-01

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Integrating mission and strategy for nonprofit organizations

This report documents a computable general equilibrium (CGE) model of the economy of Haiti, emphasizing energy use in agriculture. CGE models compare favorably with econometric models for developing countries in terms of their ability to take advantage of available data. The model of Haiti contains ten production sectors: manufacturing, services, transportation, electricity, rice, coffee, sugar cane, sugar refining, general agriculture, and fuelwood and charcoal. All production functions use functional forms which permit factor substitution. Consumption is specified for three income categories of consumers and a government sector with a linear expenditure system (LES) of demand equations. The economy exports four categories of products and imports six. Balanced trade and capital accounts are required for equilibrium. Total sectoral allocations of land, labor and capital are constrained to equal the quantities of these inputs in the Haitian economy as of the early ...

1988-02-01

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Technology Strategy Board

Integrating mission and strategy for nonprofit organizations

2005-01-01

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Timber Harvest Allocation Model

Technology Strategy Board Driving Innovation ...Technology Strategy 2009-2012 ... The vision of the Technology Strategy Board is for the UK to be a global leader in innovation

38

NASA Information Technology Requirement Main Menu

Abstract: HARVEST was designed as a strategic research and planning tool, allowing assessment of the spatial pattern consequences of broad timber management ...

39

An application of possibilistic programming to the fuzzy location?allocation problems

Headquarters Centrally-Funded Information Technology (IT) Resource Allocation .... Information Technology Policy Formulation Process ...

40

British Library Electronic Table of Contents (United Kingdom)

This paper considers location?allocation problem in the real uncertain world and develops a possibilistic non-linear programming model to deal with this problem. Fuzzy decision making in fuzzy environment concept is used to determine possibility distribution of location and allocation variables. To solve this model, a novel approach based on genetic algorithm structure is developed. As the proposed model includes both deterministic (location) and uncertain (allocation) parameters, the developed solution algorithm uses a hybrid chromosome structure. Also, to cover continuous nature of the problem and prevent GA from early convergence, a new crossover operator is introduced. Finally, performance of the developed algorithm is evaluated by an example.

2011-01-01

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The influence of MHC polymorphism on the selection of T-cell determinants of FMDV in cattle.

Tat-Neutralizing Antibodies in Vaccinated Macaques

There is a quest for the development of a new generation of vaccines consisting of well-defined subunit antigens. For a number of practical reasons it is attractive to develop vaccines on the basis...Full Text Available

1995-01-01

42

Synchronous infection of SIV and HIV in vitro for virology, immunology, and vaccine-related studies

The human immunodeficiency virus Tat protein is essential for virus replication and is a candidate vaccine antigen. Macaques immunized with Tat or chemically modified Tat toxoid having the same clade...Full Text Available

2003-03-01

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Safety and Immunogenicity of Novel Recombinant BCG and Modified Vaccinia Virus Ankara Vaccines in Neonate Rhesus Macaques ?

The development of an HIV vaccine will require a more precise understanding of the immunological and virological underpinnings of HIV infection. Magnetofection, the process of magnetizing HIV...Full Text Available

2010-01-01

44

Pathway to Licensure for Protective Antigen-based Anthrax Vaccines ...

Although major inroads into making antiretroviral therapy available in resource-poor countries have been made, there is an urgent need for an effective vaccine administered shortly after birth, which...Full Text Available

2010-08-01

45

Mothers' concept of measles and attitudes towards the measles vaccine in Ile-Ife, Nigeria.

... Weiss, S., D. Kobiler, H. Levy, H. Marcus, A. Pass, N. Rothschild, and Z ... of Bacillus anthracis spores conferred by a protective antigen-based vaccine in rabbits ...

46

Molecular characterization of a Chinese variant of the Flury-LEP strain

The attitude of Nigerian mothers, mainly Yoruba, towards measles vaccine and other aspects of prevention are influenced by different perceptions of the cause of measles. There is a significant correlation...Full Text Available

1982-09-01

47

Indian vaccine innovation: the case of Shantha Biotechnics

The entire genome of rabies virus vaccine strain Flury-LEP-C, a Chinese variant of the rabies virus vaccine strain Flury-LEP, was sequenced. The overall length of the genome of Flury-LEP-C strain was...Full Text Available

48

Cryoglobinaemia in rabbits hyperimmunized with a polyvalent pneumococcal vaccine

BackgroundAlthough the World Health Organization had recommended that every child be vaccinated for Hepatitis B by the early 1980s, large multinational pharmaceutical companies held...Full Text Available

49

Correlates to Increased Lethality of Attenuated Venezuelan Encephalitis Virus Vaccine for Immunosuppressed Hamsters.

During the anamnestic response, the sera of four rabbits immunized with a polyvalent pneumococcal vaccine contained large amounts of cryoglobulins belonging to the G and M immunoglobulin classes. These...Full Text Available

1965-10-01

50

A viral vaccine encoding PSA induces antigen spreading to a common set of self proteins in prostate cancer patients

Splenectomy or pretreatment of adult hamsters with cyclophosphamide (Cytoxan) increased the lethality of the TC-83 vaccine strain of Venezuelan encephalitis virus (VEE), inoculated subcutaneously, from 12% for normal hamsters to 75 and 76% respectively. A...

1974-01-01

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Vaccination response to tetanus toxoid and 23-valent pneumococcal vaccines following administration of a single dose of abatacept: a randomized, open-label, parallel group study in healthy subjects

PurposeWe previously reported a randomized phase II clinical trial combining a poxvirus-based vaccine encoding PSA with radiotherapy in patients with localized prostate...Full Text Available

2010-08-01

52

Long-Term Specific Immune Responses Induced in Humans by a Human Immunodeficiency Virus Type 1 Lipopeptide Vaccine: Characterization of CD8⁺-T-Cell Epitopes Recognized

The effect of abatacept, a selective T-cell co-stimulation modulator, on vaccination has not been previously investigated. In this open-label, single-dose, randomized, parallel-group, controlled study,...Full Text Available

2007-01-01

53

Comparison of a multivalent viral vaccine program versus a univalent viral vaccine program on animal health, feedlot performance, and carcass characteristics of feedlot calves

We studied the effect of booster injections and the long-term immune response after injections of an anti-human immunodeficiency virus type 1 (HIV-1) lipopeptide vaccine. This vaccine was injected alone...Full Text Available

2003-10-01

54

An Energy-Efficient Resource Allocation Scheme for Mobile Ad Hoc Computational Grids

A field study was conducted under commercial feedlot conditions at 2 sites in western Canada to determine the relative effects of a univalent viral vaccine (MLV 1) program versus a multivalent viral...Full Text Available

2003-01-01

55

British Library Electronic Table of Contents (United Kingdom)

Due to recent advancements in mobile computing and communication technologies, mobile ad hoc computational Grids are emerging as a new computing paradigm, enabling innovative applications through sharing of computing resources among mobile devices without any pre-existing network infrastructure. Energy-efficient resource allocation is one of the key issues in mobile ad hoc computational Grids due to limited battery life of mobile nodes. To reduce energy consumption, we propose a hybrid power-based resource allocation scheme for allocation of interdependent tasks to nodes within mobile ad hoc computational Grid. The basic idea is to exploit dependencies and task type, and allocate interdependent tasks to nodes accessible at minimum transmission power. We also propose a power-based algorithm...

2011-01-01

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The immunological era in melanoma treatment: new challenges for heat shock protein-based vaccine in the advanced disease

British Library Electronic Table of Contents (United Kingdom)

Introduction: Tumor-derived heat shock protein (HSP)-peptide complexes (HSPPCs) induced immunity against malignancies in preclinical trials, working across tumor types and bypassing the need to identify single immunogenic peptides. These results paved the way for the use of human gp96 obtained from autologous tumor samples as an anti-cancer vaccine. Areas covered: Autologous tumor-derived HSP gp96 peptide complex (HSPPC-96) vaccine is emerging as a tumor- and patient-specific cancer vaccine, with confirmed activity in several malignancies. It has been tested in Phase III clinical trials in advanced melanoma and kidney cancer with evidence for efficacy in patients with earlier stage disease. HSPPC-96-based vaccine demonstrated an excellent safety profile, thus emerging as a novel therapeuti...

2011-01-01

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Knowledge management process and strategy

Responses of northern forest plants to atmospheric changes

Knowledge management

2011-01-01

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Integrated Mission Specification and Task Allocation for Robot ...

This research programme has been under way since 1990 to study the long-term synergistic effects of air pollutants and changing climatic conditions on the northern forest ecosystem and to increase the knowledge of climatic change and its consequences for the fragile northern nature. Ecological, physiological, morphological and biochemical methods have been used to study the responses of forest trees, dwarf shrubs, lichens and soil biology to environmental changes. The research programme is divided into four subprojects concentrating on different ecosystem levels. The subprojects are: (1) life, growth and survival strategies of northern dwarf shrubs under the pressure of a changing environment, (2) forest trees under the impact of air pollutants, increasing CO{sub 2} and UV-B, (3) susceptibility of lichens to air pollution and climatic change and (4) impact of elevated atmospheric CO{sub 2} and O{sub 3} on soil biology with special reference to carbon ...

1996-12-31

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Bandwidth Allocation to Interactive Users in DBS-Based ...

... for team sizes ranging from 2 to 6 robots. ... intercep- tion mission, a robot must overtake a ... of unmanned underwater vehicles (UUV), unmanned aerial ...

2011-05-14

60

Analysis of Online Algorithms for Organ Allocation.

... end-to-end TCP connection from the hybrid terminal ... peculiar to self-similar stochastic processes, ... Queue First (MDQF) schemes are employed at the ...

2011-05-13

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Advances in Optimal Routing through Computer Networks

... on some results we obtained, using stochastic methods as ... choice between two customers in a queue and one ... with the terminal of edge I being the ...

1990-10-03

62

Adjustment of sperm allocation under high risk of sperm competition across taxa: a meta-analysis

... adaptive method called Shortest Queue plus Bias ... routing problem under stochastic traffic demands have ... of permits allocated to a node or terminal ...

1977-09-01

63

British Library Electronic Table of Contents (United Kingdom)

Abstract Sperm competition theory predicts that under high risk of sperm competition, males will increase the number of sperm that they allocate to a female. This prediction has been supported by some experimental studies but not by others. Here, I conducted a meta-analysis to determine whether the increase in sperm allocation under high risk of sperm competition is a generalized response across taxa. I collected data from 39 studies and 37 species. Across taxa, males under a high risk of sperm competition respond by increasing their sperm allocation (mean effect size-=-0.32). Number of offspring did not explain a significant portion of the variation in effect sizes. A traditional meta-analysis (i.e. without phylogenetic information) described the variation among effect sizes better than a...

2011-01-01

64

Current status of a hepatitis C vaccine: encouraging results but significant challenges ahead

The Case for Reactive Mass Oral Cholera Vaccinations

Persistent hepatitis C virus (HCV) infection affects 170 million people worldwide. Acute HCV infection is often asymptomatic, but many infected individuals develop persistent infections that may lead to development of end-stage liver diseases, including liver cirrhosis and hepatocellular carcinoma. Thus, an HCV vaccine that could significantly lower the chronicity rate would have a major impact on the disease burden. Unfortunately, HCV is a highly mutable virus, and escape mutations can undermine vaccine-induced virus-specific immunity. Also, HCV exists as multiple genotypes, and so genotype-specific vaccines might be required to achieve broad protection. Finally, vaccine development has been hampered by the lack of a small animal model and cell culture systems, but these are currently being established. Despite these obstacles, several vaccine candidates tested in the chimpanzee ...

2007-01-01

65

IntroductionThe outbreak of cholera in Zimbabwe intensified interest in the control and prevention of cholera. While there is agreement that safe water, sanitation, and personal...Full Text Available

66

Reversing B cell aging

Reporting Problems to FDA

Age-related alterations in the cellular composition of the B lineage are a major cause of the poor antibody response to vaccination and to infectious agents among the elderly population. The mechanisms...Full Text Available

67

Medline Plus

Enter Search terms A-Z Index Home Food Drugs Medical Devices Vaccines, Blood & Biologics Animal & Veterinary Cosmetics Radiation-Emitting Products Tobacco ...

68

Health Information for Travelers to South Africa - Travelers...

Health Information for Travelers to Somalia - Travelers' Health...

more information about this message, please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) South Africa Regions Vaccinations News & Announcements Travel...

2011-08-28

69

Health Information for Travelers to Saudi Arabia - Travelers...

more information about this message, please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) Somalia Regions Vaccinations News & Announcements Travel...

2011-08-28

70

Health Information for Travelers to Rwanda - Travelers' Health...

more information about this message, please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) Saudi Arabia Regions Vaccinations News & Announcements Travel...

2011-08-28

71

Health Information for Travelers to Mozambique - Travelers' Health...

more information about this message, please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) Rwanda Regions Vaccinations News & Announcements Travel...

2011-08-28

72

Health Information for Travelers to Malawi - Travelers' Health...

more information about this message, please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) Mozambique Regions Vaccinations News & Announcements Travel...

2011-08-28

73

Health Information for Travelers to Kenya - Travelers' Health...

more information about this message, please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) Malawi Regions Vaccinations News & Announcements Travel...

2011-08-28

74

Health Information for Travelers to Iran - Travelers' Health...

more information about this message, please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) Kenya Regions Vaccinations News & Announcements Travel Notices...

2011-08-28

75

Health Information for Travelers to Gabon - Travelers' Health...

please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) Iran Regions Vaccinations News & Announcements Travel Notices Diseases Yellow Book Contents...

2011-09-04

76

Health Information for Travelers to Ethiopia - Travelers' Health...

more information about this message, please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) Gabon Regions Vaccinations News & Announcements Travel Notices...

2011-08-28

77

Health Information for Travelers to Eritrea - Travelers' Health...

more information about this message, please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) Ethiopia Regions Vaccinations News & Announcements Travel...

2011-08-28

78

Health Information for Travelers to Equatorial Guinea - Travelers...

more information about this message, please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) Eritrea Regions Vaccinations News & Announcements Travel...

2011-08-28

79

Health Information for Travelers to Djibouti - Travelers' Health...

more information about this message, please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) Equatorial Guinea Regions Vaccinations News & Announcements...

2011-08-28

80

Health Information for Travelers to Democratic Republic of the...

more information about this message, please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) Djibouti Regions Vaccinations News & Announcements Travel...

2011-08-28

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

81

Health Information for Travelers to Antarctica - Travelers' Health...

more information about this message, please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) Democratic Republic of the Congo Regions Vaccinations News &...

2011-08-28

82

more information about this message, please visit this page: About CDC.gov. Travelers' Health Home Destinations (238) Antarctica Regions Vaccinations News & Announcements Travel...

2011-08-28

83

Diphtheria in Europe.

Controlling Endemic Cholera with Oral Vaccines

A letter of inquiry was sent to 21 countries in Europe to ascertain their experience of diphtheria during the last 20 years. An analysis of the 15 replies showed that all relied on childhood vaccination...Full Text Available

1984-12-01

84

Bioterrorism and Biocrimes: The Illicit Use of Biological Agents ...

BackgroundAlthough advances in rehydration therapy have made cholera a treatable disease with low case-fatality in settings with appropriate medical care, cholera continues...Full Text Available

2007-11-01

85

A Novel Multi-Antigen Virally Vectored Vaccine against Mycobacterium avium Subspecies paratuberculosis

... view on the utility of such attacks, see JH Rothschild, Tomorrow's Weapons ... Aum Shinrikyo may have had a stolen vaccine anthrax strain incapable ...

2001-02-01

86

Decomissioning Strategies for Facilities Using Radioactive Material

BackgroundMycobacterium avium subspecies paratuberculosis causes systemic infection and chronic intestinal inflammation in many species including...Full Text Available

87

T Cell Responses to the RTS,S/AS01_E and RTS,S/AS02_D Malaria Candidate Vaccines Administered According to Different Schedules to Ghanaian Children

Decomissioning Strategies for Facilities Using Radioactive Material

2007-01-01

88

Preliminary Assessment of the Safety and Immunogenicity of a New CTX?-Negative, Hemagglutinin/Protease-Defective El Tor Strain as a Cholera Vaccine Candidate

BackgroundThe Plasmodium falciparum pre-erythrocytic stage candidate vaccine RTS,S is being developed for protection of young children against...Full Text Available

89

Potent immune responses and in vitro pro-inflammatory cytokine suppression by a novel adenovirus vaccine vector based on rare human serotype 28

Vibrio cholerae 638 (El Tor, Ogawa), a new CTXΦ-negative hemagglutinin/protease-defective strain that is a cholera vaccine candidate, was examined for safety and immunogenicity...Full Text Available

1999-02-01

90

Adenovirus vaccine vectors derived from rare human serotypes have been shown to be less potent than serotype 5 (Ad5) at inducing immune responses to encoded antigens. To identify highly immunogenic...Full Text Available

2010-08-09

91

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Molecular Characterization of a Haemaphysalis longicornis Tick Salivary Gland-Associated 29-Kilodalton Protein and Its Effect as a Vaccine against Tick Infestation in Rabbits

...INFORMATION Diarrhoeal disease Food safety and foodborne illness Enterohaemorrhagic Escherichia coli (EHEC) Cholera WHO PROGRAMMES AND ACTIVITIES Child and Adolescent Health and Development (...FOS) Initiative for Vaccine Research (IVR) TECHNICAL INFORMATION Vaccine research: diarrhoeal diseases Cholera Water-related diseases Household water treatment and safe storage WHO Global Salm-Surv ...PUBLICATIONS Diarrhoea: child and adolescent health Diarrhoea: cholera RELATED TOPICS - Child health - Water - Food safety - Cholera - Travel - Breastfeeding ...

92

Efficacy of a heat inactivated hepatitis B vaccine in male homosexuals: outcome of a placebo controlled double blind trial.

The use of tick vaccines in mammalian hosts has been shown to be the most promising alternative tick control method to current use of acaricides, which suffers from a number of limitations. However,...Full Text Available

1999-04-01

93

Effects of 2 commercially-available 9-way killed vaccines on milk production and rectal temperature in Holstein-Friesian dairy cows.

The efficacy of a heat inactivated hepatitis B virus vaccine, containing 3 micrograms hepatitis B surface antigen (HBsAg), was studied in a high risk group of 800 susceptible homosexual men by a randomised...Full Text Available

1983-04-23

94

A recombinant Yellow Fever 17D vaccine expressing Lassa virus glycoproteins

Veterinarians and farmers employing multivalent killed vaccines in lactating dairy cows have reported transient losses in milk production. Few studies have quantified this loss. In this report, effects...Full Text Available

2001-10-01

95

A Randomized Trial Assessing the Safety and Immunogenicity of AS01 and AS02 Adjuvanted RTS,S Malaria Vaccine Candidates in Children in Gabon

The Yellow Fever Vaccine 17D (YFV17D) has been used as a vector for the Lassa virus glycoprotein precursor (LASV-GPC) resulting in construction of YFV17D/LASV-GPC recombinant virus. The virus...Full Text Available

2006-02-20

96

Management of fire and industrial safety - challenges during commissioning of a NPP

BackgroundThe malaria vaccine candidate antigen RTS,S includes parts of the pre-erythrocytic stage circumsporozoite protein fused to the Hepatitis B surface antigen. Two Adjuvant...Full Text Available

97

Coping Strategies of Family Members of Hospitalized Psychiatric Patients

Construction and commissioning period of NPP are reduced world over drastically by stringent schedule for financial and economic reasons. For meeting the schedule, commissioning of components and systems are started immediate after installation, while construction activities are continued in parallel at the same place. Parallel activities' and 'Time Constraint' have brought new challenges to 'Management of Fire and Industrial Safely' during commissioning. An innovative approach was used during such phase of commissioning of TAPP-3 and 4. This paper outlines challenges encountered during this phase and special approach and measures used to meet those challenges. This paper also outlines problems encountered during implementation of these measures and subsequent change in approach to ensure smooth and safe execution of activities. Primarily, challenges were conflicting requirements by various agencies to carryout commissioning in parallel with construction activities concurrently. Main ...

2006-11-13

98

Serological testing-An alternative to boosters?

This exploratory research paper investigated the coping strategies of families of hospitalized psychiatric patients and identified their positive and negative coping strategies. In this paper, the coping...Full Text Available

2011-01-01

99

British Library Electronic Table of Contents (United Kingdom)

The issue of the duration of immunity, particularly for the modified live viral components of veterinary vaccines, has been a significant part of the recent vaccination debate. One manufacturer has increased the recommended booster interval for these components to 3 years give name and another now states `up to 4 years' immunity.There remain many unanswered questions regarding this duration of immunity (DOI). Studies suitable for data sheet claims are time consuming and costly and can only be performed in laboratory dogs under tightly controlled conditions. Evidence from rabies serology testing in the UK shows that the response of individual animals to routine vaccination is highly variable. Much of the published field evidence on the persistence of antibody titres originates from North Am...

2006-01-01

100

Immunogenicity, efficacy, safety and effectiveness of pneumococcal conjugate vaccines (1998-2006)

British Library Electronic Table of Contents (United Kingdom)

In this paper we present an overview of the literature on efficacy and safety trials of the various pneumococcal conjugate vaccines on the market (PCV7) and in development (PCV9, PCV11 and allegedly PCV10 and PCV13), as well as of observations from post-licensure studies. Seven- (PCV7) and nine-valent PCV (PCV9) are reported to be sufficiently immunogenic after administration of a 3+1 schedule in infants in various RCTs. PncOMPC (PCV7 with a protein of N. meningitidis as a carrier) is less immunogenic, though this may have no repercussions for the protective efficacy against clinical disease. PCV7 is 82-97% efficacious against vaccine serotype (VT) IPD, 90% efficacious against (clinically diagnosed) pneumococcal pneumonia, and, like the 11-valent PCV, 57% efficacious against VT acute otiti...

2007-01-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

101

An oral nervous necrosis virus vaccine using Vibrio anguillarum as an expression host provides early protection

British Library Electronic Table of Contents (United Kingdom)

Oral vaccination is the most desirable immunization method by which to prevent fish disease occurring at the early larval stage. We developed an Escherichia coli-based oral nervous necrosis virus (NNV) subunit vaccine and demonstrated its effectiveness in orange spotted grouper (Epinephelus coioides) fry. However, the incubation period was determined to be over 2weeks. To enhance the efficacy and shorten the incubation period, a safe and digestible biological adjuvant should be found. Vibrio anguillarum, a common marine bacterium with immune-stimulatory capability was selected as an expression host. An expression vector containing its heat shock protein 60 gene (groE) as an inducible promoter was constructed to express recombinant NNV coat protein as an antigen. The recombinant V. anguilla...

2011-01-01

102

Strategies for Protecting Waste Collectors' Health and Safety

Full Throttle 122 Strategies to Supercharge Your Performance at Work

Full Text Available

2010-06-01

103

A Study on the Convergence of the Evolution Strategies based on Learning

Full Throttle

2009-01-01

104

Who Should Receive Life Support During a Public Health Emergency? Using Ethical Principles to Improve Allocation Decisions

Full Text Available

1999-12-01

105

Technology assessment and resource allocation for predictive genetic testing: A study of the perspectives of Canadian genetic health care providers

A public health emergency such as an influenza pandemic will lead to shortages of mechanical ventilators, critical care beds, and other potentially life saving treatments. This will raise difficult...Full Text Available

2009-01-20

106

Surge Capacity for Response to Bioterrorism in Hospital Clinical Microbiology Laboratories

BackgroundWith a growing number of genetic tests becoming available to the health and consumer markets, genetic health care providers in Canada are faced with the challenge of developing...Full Text Available

107

Strength training for wheelchair users.

Surge capacity is the ability to rapidly mobilize to meet an increased demand. While large amounts of federal funding have been allocated to public health laboratories, little federal funding has been...Full Text Available

2003-12-01

108

Sperm competition games: optimal sperm allocation in response to the size of competing ejaculates

Sedentary adult males with spinal lesions, all habitual wheelchair users, were allocated to exercise (n = 11) and control (n = 4) groups. A Cybex II dynamometer was used to assess peak power, average...Full Text Available

1990-03-01

109

Quality assessment of reporting of randomization, allocation concealment, and blinding in traditional chinese medicine RCTs: A review of 3159 RCTs identified from 260 systematic reviews

Sperm competition theory predicts that when males are certain of sperm competition, they should decrease sperm investment in matings with an increasing number of competing ejaculates. How males should...Full Text Available

2007-01-22

110

Frozen shoulder: prospective clinical study with an evaluation of three treatment regimens.

BackgroundRandomized controlled trials (RCTs) which are of poor quality tend to exaggerate the effect estimate and lead to wrong or misleading conclusions. The aim of this study...Full Text Available

111

Economics of Reliability Improvement for Space Launch Vehicles.

Forty-two patients with frozen shoulder were followed up closely for eight months. They were all taught pendular exercises and randomly allocated to one of four treatment groups: (a) intraarticular...Full Text Available

1984-06-01

112

Civil and Military Satellite Communications: A Systems ...

Present methods for planning reliability improvement of launch vehicles are reviewed. A theoretical criterion for optimum allocation of resources for reliability improvement exists that requires equal marginal failure reduction for all elements to be impr...

1968-01-01

113

Goals, Strategies, and Top Accomplishments, May 2010 (Fact Sheet)

... to-noise density than the uplink budget has (74.2 ... in heav:, point-to-point link applications with ... 11.7 Expanded bands allocated (Ku band) (500 MHz ...

1991-02-01

114

Optimization of cleaning timing and load allocation in steam generator management

Fact sheet describes the goals, strategies, and top accomplishments of the Clean Cities program.

2010-05-01

115

Implementation of the national desalination and water purification technology roadmap : structuring and directing the development of water supply solutions.

A method for cleaning timing optimization in a parallel steam generator system is described. The method is based on the minimization of a suitable objective function, and takes into account the load allocation on steam generators. In order to establish appropriate fouling growth models the mechanism of the particle deposition and removal on heat transfer surfaces is analyzed. The objective function is related to the short time management costs which are based on depreciation of steam generators, fuel costs and the costs of cleaning interventions. The optimization problem is described; a direct one level method is compared with a two level method. Some applications and their results are reported and discussed. (author)

1998-03-01

116

Congestion cost allocation method in a pool model

In the United States, economic growth increasingly requires that greater volumes of freshwater be made available for new users, yet supplies of freshwater are already allocated to existing users. Currently, water for new users is made available through re-allocation of xisting water supplies-for example, by cities purchasing agricultural water rights. Water may also be made available through conservation efforts and, in some locales, through the development of ''new'' water from non-traditional sources such as the oceans, deep aquifer rackish groundwater, and water reuse.

2006-06-01

117

Therapeutic Vaccination in Chronic Hepatitis B: Preclinical Studies in the Woodchuck

The congestion cost caused by transmission capacities and voltage limit is an important issue in a competitive electricity market. To allocate the congestion cost equitably, the active constraints in a constrained dispatch and the sequence of these constraints should be considered. A multi-stage method is proposed which reflects the effects of both the active constraints and the sequence. In a multi-stage method, the types of congestion are analysed in order to consider the sequence, and the relationship between congestion and the active constraints is derived in a mathematical way. The case study shows that the proposed method can give more accurate and equitable signals to customers. (Author)

2003-09-01

118

The hemoglobins of the trematodes Fasciola hepatica and Paramphistomum epiclitum: A molecular biological, physico-chemical, kinetic, and vaccination study

Recommended treatment of chronic hepatitis B with interferon-α and/or nucleos(t)ide analogues does not lead to a satisfactory result. Induction of HBV-specific T cells by therapeutic...Full Text Available

2010-01-01

119

Testing the Efficacy of a Multi-Component DNA-Prime/DNA-Boost Vaccine against Trypanosoma cruzi Infection in Dogs

The trematode Fasciola hepatica (Fa.he.) is a common parasite of human and livestock. The hemoglobin (Hb) of Fa.he., a potential immunogen, was chosen for characterization...Full Text Available

2008-10-01

120

Taking social relationships seriously: Lessons learned from the informed consent practices of a vaccine trial on the Kenyan Coast

BackgroundTrypanosoma cruzi, the etiologic agent of Chagas Disease, is a major vector borne health problem in Latin America and an emerging...Full Text Available

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

121

Syndecan-Fc Hybrid Molecule as a Potent In Vitro Microbicidal Anti-HIV-1 Agent?

AbstractIndividual informed consent is a key ethical obligation for clinical studies, but empirical studies show that key requirements are often not met. Common recommendations to strengthen...Full Text Available

2008-09-01

122

Serum Concentrations of Antibodies Against Vaccine Toxoids in Children Exposed Perinatally to Immunotoxicants

In the absence of a vaccine, there is an urgent need for the development of safe and effective topical microbicides to prevent the sexual transmission of human immunodeficiency virus type 1 (HIV-1)....Full Text Available

2010-07-01

123

Rubella screening and vaccination program for US Air Force trainees: an analysis of findings.

BackgroundPolychlorinated biphenyls (PCBs) may cause immunotoxic effects, but the detailed dose–response relationship and possible vulnerable time windows of exposure are...Full Text Available

2010-10-01

124

Regulatory compliance | Mott MacDonald

A preventive medicine program of rubella control for trainees at the Air Force Military Training Center, Lackland AFB, Texas, was begun in October 1977. Incoming trainees were screened for rubella susceptibility,...Full Text Available

1982-03-01

125

Prevention of clinical coliform mastitis in dairy cows by a mutant Escherichia coli vaccine.

...broad range of experience in designing and building research and development laboratories for products such as vaccines, blood and sera, biological products, medical devices, solid dosage forms , highly potent products and cytotoxic material. We also have experience in a range of modular laboratories for TSE research, ...

126

Polyantigenic Interferon-? Responses Are Associated with Protection from TB among HIV-Infected Adults with Childhood BCG Immunization

A prospective cohort study was undertaken in two commercial California dairies. The treatment group, 246 cows, received three doses of a whole cell bacterin of J5 Escherichia coli (mutant of E. coli...Full Text Available

1989-07-01

127

Plasminogen-¹²⁵I responses in dogs to a single injection of urokinase and typhoid vaccine and to vascular injury

BackgroundSurrogate immunologic markers for natural and vaccine-mediated protection against tuberculosis (TB) have not been identified.MethodsHIV-infected...Full Text Available

128

Peru-15, an improved live attenuated oral vaccine candidate for Vibrio cholerae O1.

In vivo plasminogen responses to various stimuli were studied. Plasminogen-¹²⁵I was prepared and used first for metabolic studies of plasminogen in control dogs. The average results were:...Full Text Available

1972-06-01

129

Peptide Nanoparticles as Novel Immunogens: Design and Analysis of a Prototypic Severe Acute Respiratory Syndrome Vaccine

Cholera vaccine candidate Peru-15 was derived from a Vibrio cholerae O1 El Tor Inaba strain by deleting the cholera toxin genetic element, introducing the gene encoding cholera toxin B subunit into recA, and screening for nonmotility. In a controlled study, Peru-15 (2 x 10(8) cfu) was administered to 11 volunteers. No vaccinee developed diarrhea, and 10 of 11 had > 4-fold rises in vibriocidal antibody titers. One month later, 5 vaccinees and 5 control volunteers were challenged with wild type V. cholerae O1. Four of 5 controls developed diarrhea (mean, 1.9 L). Two Peru-15 vaccinees developed diarrhea, 1 with < 0.3 L and 1 with approximately 1.0 L; this latter volunteer had not developed a significant vibriocidal immune response to vaccination. Peru-15 shows promise as a single-dose, oral cholera vaccine that is safe, immunogenic, and protective. PMID:7561195

1995-10-01

130

Passive immunity to feline leukemia: evaluation of immunity from dams naturally infected and experimentally vaccinated.

Severe acute respiratory syndrome (SARS) is an infectious disease caused by a novel coronavirus that cost nearly 800 lives. While there have been no recent outbreaks of the disease, the threat...Full Text Available

2009-01-01

131

LOUSE-BORNE BACTERIAL PATHOGENS IN LICE (PHTHIRAPTERA) OF RODENTS AND CATTLE FROM EGYPT

Antibodies against feline leukemia virus (FeLV) and the feline oncornavirus-associated cell membrane antigen (FOCMA) were transferred from pregnant cats to their suckling kittens. All of these kittens...Full Text Available

1977-04-01

132

In vitro antigen-induced antibody responses to hepatitis B surface antigen in man. Kinetic and cellular requirements.

... were erroneous. The oriental rat flea, Xenopsylla cheopis Rothschild, is considered to be the primary vector of ... laboratory and production of Weigl's exanthematous typhus vaccine. In Maintenance of hum...

133

Improvement of a Dendritic Cell-Based Therapeutic Cancer Vaccine with Components of Toxoplasma gondii?

In this report we define the parameters of the human immune response after immunization with hepatitis B vaccine. 2 wk after booster immunization, there is significant spontaneous secretion of antibody...Full Text Available

1984-10-01

134

Immunization of foxes by the intestinal route using an inactivated rabies vaccine.

The use of dendritic cells (DCs) as a cellular adjuvant is a promising approach to the immunotherapy of cancer. It has previously been demonstrated that DCs pulsed ex vivo with Toxoplasma gondii...Full Text Available

2009-10-01

135

Genomic Expression Libraries for the Identification of Cross-Reactive Orthopoxvirus Antigens

Approximately 30% of foxes given two doses of an inactivated rabies antigen delivered directly into the intestinal tract developed an immune response as measured by rabies serum neutralizing antibodies....Full Text Available

1989-01-01

136

Genomic Content of Bordetella pertussis Clinical Isolates Circulating in Areas of Intensive Children Vaccination

Increasing numbers of human cowpox virus infections that are being observed and that particularly affect young non-vaccinated persons have renewed interest in this zoonotic disease. Usually causing...Full Text Available

137

Evaluation of Two Homologous Proline-Rich Proteins of Coccidioides posadasii as Candidate Vaccines against Coccidioidomycosis?

BackgroundThe objective of the study was to analyse the evolution of Bordetella pertussis population and the influence of herd immunity in different areas of the...Full Text Available

138

Dengue virus-specific murine T-lymphocyte proliferation: serotype specificity and response to recombinant viral proteins.

Evaluation of the protective efficacy of recombinant T-cell-reactive proteins of Coccidioides posadasii in a murine model of coccidioidomycosis has led to the discovery of potential...Full Text Available

2007-12-01

139

Dengue virus protein recognition by virus-specific murine CD8+ cytotoxic T lymphocytes.

Definition of the T-lymphocyte responses to dengue viruses should aid in the development of safe and effective vaccines and help to explain the pathophysiology of dengue hemorrhagic fever and dengue...Full Text Available

1989-06-01

140

CDC - Seasonal Influenza (Flu) - Questions and Answers - Guillain...

The identification of the protein targets for dengue virus-specific T lymphocytes may be useful for planning the development of subunit vaccines against dengue. We studied the recognition by murine...Full Text Available

1993-02-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

141

CDC - Malaria - Malaria Worldwide - How Can Malaria Cases and...

Effectiveness Flu Shot Nasal Spray Vaccine (LAIV) Thimerosal Guillain-Barré Syndrome (GBS) Antiviral Drugs: Key Facts Antiviral Drugs: Q&A Antiviral Drug Resistance Links,...

2011-09-24

142

Auditing the Management of Vaccine-Preventable Disease Outbreaks: The Need for a Tool

vaccination card during trial enrollment at the KEMRI/CDC site in Kenya. (Alan Rubin, KEMRI) KEMRI Clinical Officer Paul Ogai reviews a prospective participant's...

2011-09-24

143

Immunological correlates for protection against intranasal challenge of Bacillus anthracis spores conferred by a protective antigen-based vaccine in rabbits.

Public health activities, especially infectious disease control, depend on effective teamwork. We present the results of a pilot audit questionnaire aimed at assessing the quality of public health services...Full Text Available

144

Immunogenicity, efficacy, safety and effectiveness of pneumococcal conjugate vaccines (1998-2006).

Correlates between immunological parameters and protection against Bacillus anthracis infection in animals vaccinated with protective antigen (PA)-based vaccines could provide surrogate markers to evaluate the putative protective efficiency of immunization in humans. In previous studies we demonstrated that neutralizing antibody levels serve as correlates for protection in guinea pigs (S. Reuveny et al., Infect. Immun. 69:2888-2893, 2001; H. Marcus et al., Infect. Immun. 72:3471-3477, 2004). In this study we evaluated similar correlates for protection by active and passive immunization of New Zealand White rabbits. Full immunization and partial immunization were achieved by single and multiple injections of standard and diluted doses of a PA-based vaccine. Passive immunization was carried out by injection of immune sera from rabbits vaccinated with PA-based vaccine prior to ...

2006-01-01

145

Genetic control of immune response to pseudorabies and atrophic rhinitis vaccines: II. Comparison of additive direct and maternal genetic effects.

In this paper we present an overview of the literature on efficacy and safety trials of the various pneumococcal conjugate vaccines on the market (PCV7) and in development (PCV9, PCV11 and allegedly PCV10 and PCV13), as well as of observations from post-licensure studies. Seven- (PCV7) and nine-valent PCV (PCV9) are reported to be sufficiently immunogenic after administration of a 3+1 schedule in infants in various RCTs. PncOMPC (PCV7 with a protein of N. meningitidis as a carrier) is less immunogenic, though this may have no repercussions for the protective efficacy against clinical disease. PCV7 is 82-97% efficacious against vaccine serotype (VT) IPD, 90% efficacious against (clinically diagnosed) pneumococcal pneumonia, and, like the 11-valent PCV, 57% efficacious against VT acute otitis media. Naturally, it would be of paramount public health interest if the same levels of efficacy and effectiveness could be achieved with fewer doses. ...

2006-12-04

146

Spectrum Allocation in Two-Tier Networks

Data from 52 litters farrowed in two seasons of a cross-fostering experiment were analyzed to estimate variances and covariances for additive direct and maternal genetic effects on immune response to pseudorabies virus and B. bronchiseptica vaccine. Twenty purebred boars and 44 sows of the Duroc, Landrace and Yorkshire breeds were used. Immune response was measured after vaccine challenge. A modified-live pseudorabies (PR) vaccine was administered to piglets at 28 d of age; response was measured by log2 serum neutralization titers at 56 d. An inactivated B. bronchiseptica bacterin was administered at 28, 42 and 112 d. Antibody levels were measured relative to positive and negative controls at 28, 56 and 119 d by using an enzyme-linked immunosorbent assay (ELISA). Results from this study for heritability were .18 +/- .09 for PR titer and .15 +/- .07 and .52 +/- .15 for 56- and 119-d ELISA values, respectively. The ...

1987-02-01

147

Effect of two-stage injection on fundamental combustion characteristics of DI diesel engine; Chokusetsu funshashiki diesel kikan no nidan funshaka ni yoru kihon nensho tokusei no henka

Two-tier networks, comprising a conventional cellular network overlaid with shorter range hotspots (e.g. femtocells, distributed antennas, or wired relays), offer an economically viable way to improve cellular system capacity. The capacity-limiting factor in such networks is interference. The cross-tier interference between macrocells and femtocells can suffocate the capacity due to the near-far problem, so in practice hotspots should use a different frequency channel than the potentially nearby high-power macrocell users. Centralized or coordinated frequency planning, which is difficult and inefficient even in conventional cellular networks, is all but impossible in a two-tier network. This paper proposes and analyzes an optimum decentralized spectrum allocation policy for two-tier networks that employ frequency division multiple access (including OFDMA). The proposed allocation is optimal in terms of Area Spectral Efficiency (ASE), and is ...

2008-01-01

148

Effect of increased CO sub 2 and decreased O sub 2 on photosynthesis, and carbon allocation in source leaves

Combustion characteristics and engine performances of a two-stage injection DI diesel engine were experimentally investigated. Two-stage injection was achieved by using two injection pumps. Injection timing and fuel allocation ratio between first and second injection were widely controlled, Engine performance of a two-stage injection diesel engine was compared with that of a single injection diesel engine with early timing injection. The heat release rate was analyzed to understand the combustion phenomena in a two-stage injection diesel engine. As a result, NO emission of two-stage injection diesel engine was improved when the first injection timing is early. The various pattern of heat release rate appeared with the change of a fuel allocation ratio. It was greatly affected by the first injection spray impinged on the cylinder wall or the piston top. The trade-off tendency between NO and smoke was influenced by the fuel ...

2000-06-25

149

Assessing the Significance of Above- and Belowground Carbon Allocation of Fast- and Slow-Growing Families of Loblolly Pine - Final Report

The effect of raising the rate of photosynthesis on the allocation of carbon between sucrose and starch was studied by means of steady-state radiolabeling. Sugar beet source leaves on intact plants were exposed to ambient levels of CO{sub 2} and O{sub 2} for 3 hrs. Next CO{sub 2} was raised to 600 {mu}LL{sup {minus}3} for 3 hrs then O{sub 2} was decreased to 2% for 3 hrs. Rates of net carbon exchange (NCE), export, and starch and sucrose synthesis were measured. NCER increased by 30% under the combined treatments and the proportion of photosynthate allocated to starch and to sucrose did not change. When O{sub 2} concentration was lowered, NCER increased but export did not and sucrose accumulated. This observation, and our earlier conclusion that export rate usually equals sucrose synthesis rate, lead us to conclude that low O{sub 2} directly inhibited export. Low O{sub 2} treatment causes sucrose to accumulate in a sugar beet leaf which usually ...

1990-05-01

150

Tropical Deforestation and Climate Change: Towards an International Mitigation Strategy

During this project we experimentally evaluated the below-ground biomass and carbon allocation and partitioning of four different fast- and slow-growing families of loblolly pine located in Scotland County, NC, in an effort to increase the long-term performance of the crop. The trees were subjected to optimal nutrition and control since planting in 1993. Destructive harvests in 1998 and 2000 were used for whole?plant biomass estimates and to identify possible family differences in carbon acquisition (photosynthesis) and water use efficiency. At regular intervals throughout each year we sampled tissues for carbohydrate analyses to assess differences in whole-tree carbon storage. Mini rhizotron observation tubes were installed to monitor root system production and turnover. Stable isotope analysis was used to examine possible functional differences in water and nutrient acquisition of root systems between the various families. A genetic dissection of root ontogenic ...

2001-03-01

151

The Allocation of Treatment Responsibility scale: A novel tool for assessing patient and caregiver management of pediatric medical treatment regimens

This dissertation evaluates recent proposals to include tropical deforestation into international climate change mitigation strategies. The research ... ...

152

British Library Electronic Table of Contents (United Kingdom)

Pai ALH, Gray E, Kurivial K, Ross J, Schoborg D, Goebel J. The Allocation of Treatment Responsibility scale: A novel tool for assessing patient and caregiver management of pediatric medical treatment regimens. Pediatr Transplantation 2010: 14:993 999. 2010 John Wiley & Sons A/S. Abstract: The purpose of the current study is to report preliminary psychometric properties of the ATR scale, a brief measure of the distribution of treatment tasks across the family members of children with a kidney transplant. Pediatric patients with renal transplants (ages 7 18 yr) and their caregivers completed the ATR and measures of adherence and family functioning. Internal consistency for the ATR (total score and subscales) was strong (range = 0.75 0.93). Validity for the ATR was supported by significant co...

2010-01-01

153

Sex starved: do resource-limited males ensure fertilization success at the expense of precopulatory mating success?

British Library Electronic Table of Contents (United Kingdom)

Theory predicts trade-offs between investment in various life history traits, and it is also now generally accepted that reproduction is costly for males. Males must therefore optimize resource allocation across several episodes of reproduction, and this includes investment in both pre- and postcopulatory fitness components. We investigated this in the sperm-polymorphic Indian meal moth, Plodia interpunctella. Resource-limited males were smaller, and had decreased precopulatory mating success, measured as lifetime number of matings. However, they transferred similar numbers of fertile sperm as males reared under high-quality larval conditions, and more nonfertile sperm. By mating less frequently, resource-limited males may allocate sufficient resources to the matings they achieve to ensure...

2011-01-01

154

How the World Bank funds protected areas

British Library Electronic Table of Contents (United Kingdom)

Abstract The World Bank is the largest international funder of biodiversity conservation. It invests in protected areas to conserve species and spaces, protect ecosystems, and provide food, shelter, and other ecosystem services to local communities. It spends on average, $275 million annually supporting parks in developing countries. We examined their protected areas investment portfolio from 1988 to 2008 to understand how they allocate these funds. We found that more money is allocated to countries with progressively larger GDPs. Many, but not all, of these investments correlate with consensus opinions of high biodiversity priorities. But the World Bank's investments are not proportional; poorer countries receive relatively more funds than richer ones, regardless of biodiversity importanc...

2011-01-01

155

Effects of population allocation of the electric power systems from the viewpoint of combined heat and power installation

Discriminating Males and Unpredictable Females: Males Bias Sperm Allocation in Favor of Virgin Females

Recently it is strongly required to reduce energy consumption to cope with the global warming. Since energy consumption in commercial and residential sectors are increasing while industrial sector is almost constant in Japan, policies to lead energy conservation in urban areas is quite important. This study aims at investigating the performance of urban energy systems which install combined heat and power (CHP) as a district heating and cooling (DHC) plant and the influence of CHP on the structure of electric power systems of utilities. The behavior of energy technologies and the possibility of energy conservation are evaluated based on an optimization model with respect to total system cost. Sensitivity analysis of population allocation into urban areas indicates that fossil fuel consumption varies in the range of 10--20% compared with conventional systems.

1997-12-31

156

British Library Electronic Table of Contents (United Kingdom)

Abstract When both sexes mate with multiple partners, theory predicts that males should adjust their investment in ejaculates in response to the risk and/or intensity of sperm competition. Here, we demonstrate that, in the harlequin beetle riding pseudoscorpion, Cordylochernes scorpioides, males use cues deposited on females by previous males to distinguish between virgin, once-mated, and multiply-mated females and adjust sperm allocation accordingly. Sperm number declined in direct proportion to the number of previous males, with virgin females receiving nearly three times more sperm than females exposed to three previous males. Given the lack of first-male sperm precedence in C.scorpioides, this pattern is not consistent with current sperm competition models and appears best explained by...

2011-01-01

157

Differences in morphology, gas exchange and root hydraulic conductance before planting in Pinus canariensis seedlings growing under different fertilization and light regimes

British Library Electronic Table of Contents (United Kingdom)

As the main forestry species in the Canary Islands (Spain), Pinus canariensis is frequently used in afforestation programs. Several nursery techniques are commonly employed to modify its morphology and physiology with the aim of improving post-planting survival and growth. In this work, we studied how fertilization and light regime treatments applied during the nursery period modify biomass allocation patterns and produce effects in gas exchange and root hydraulic conductance. Seedlings were grown for a 6-month period in the nursery under two light regimes (full sunlight and 40% PAR reduction), and three fertilization levels were applied in each light regime. Morphology, biomass allocation patterns, leaf gas exchange and hydraulic conductance of the whole root system were evaluated. Fertil...

2010-01-01

158

Customer and service profitability

Ambiguity aversion and trade

The rapid pace of competitive change in the generation sector has pushed electric utilities to rethink the concept of being obligated to serve all customers and with this change, the notion of measuring customer profitability is also being redefined. Traditionally, uniform services were provided to all customers. Rates were based on each customer classes` contribution to average costs, and consequently return was equally allocated across all customer segments. Profitability was defined strictly on an aggregate basis. The increasing demand for choice by electric customers will require electricity providers to redefine if not who they serve, than certainly how they provide differentiated services tailored to specific customer segments. Utilities are beginning to analyze the value, or profitability, of offering these services. Aggregate data no longer provides an accurate assessment of how resources should be allocated most efficiently. As ...

1996-03-01

159

British Library Electronic Table of Contents (United Kingdom)

What is the effect of ambiguity aversion on trade? Although in a Bewley?s model, ambiguity aversion always leads to less trade; in other models, this is not always true. However, we show that if the endowments are unambiguous, then more ambiguity aversion implies less trade for a very general class of preferences. The reduction in trade caused by ambiguity aversion can be as severe as to lead to no trade. In an economy with MEU decision makers, we show that if the aggregate endowment is unanimously unambiguous, then every Pareto optima allocation is also unambiguous. We also characterize the situation in which every unanimously unambiguous allocation is Pareto optimal. Finally, we show how our results can be used to explain the home-bias effect. As a useful result for our methods, we also ...

2011-01-01

160

Serotypes and susceptibilities of paediatric clinical isolates of Streptococcus pneumoniae in Crete, Greece, before and after the heptavalent pneumococcal conjugate vaccine.

Construction and evaluation of a double mutant of Shigella flexneri as a candidate for oral vaccination against shigellosis.

All Streptococcus pneumoniae strains isolated from paediatric clinical samples at Heraklion University General Hospital in the 10-year period 2000-2009 were tested for serotype and susceptibility to antimicrobials. Among a total of 258 strains, 159 were isolated in the 5-year period 2000-2004, before the introduction of the heptavalent pneumococcal conjugate vaccine (PCV7), and 99 in the post-PCV7 5-year period 2005-2009. The prevalence of PCV7-included serotypes decreased in the post-PCV7 period (p?=?0.0002), but an increase was observed for serotypes 7F (p?=?0.002) and 19A (p?=?0.004). Pan-susceptibility rates and susceptibility to cotrimoxazole increased in the post-PCV7 period (p?=?0.01 and p?=?0.008, respectively), but serotype 19A emerged as a contributor to multi-resistance (p?=?0.007). PCV7 was followed by decreased S. pneumoniae resistance and prevalence of vaccine-related serotypes but increased prevalence of serotypes 7F and 19A. ...

2010-07-10

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161

Intravaginal immunization using the recombinant HIV-1 clade-C trimeric envelope glycoprotein CN54gp140 formulated within lyophilized solid dosage forms

Based on studies on the genetic and molecular basis of Shigella flexneri invasive properties, we have constructed and evaluated a double mutant of S. flexneri serotype 5 for utilization as a live attenuated oral vaccine against shigellosis. The first mutation, icsA, blocks intracellular spread of bacteria as well as cell-to-cell infection. It affects the capacity of the invasive pathogen to form large abscesses in epithelia. The second mutation, iuc, eliminates production of the siderophore aerobactin thus impairing growth of the bacterium within tissues. This double mutant, SC5700 appeared safe when administered intragastrically to macaque monkeys as three doses (5 x 10(10) c.f.u. each) at weekly intervals. Protection against a challenge by the wild type isolate (M90T) was observed 4 weeks after the last vaccine inoculation. Duration of carriage was considerably reduced as compared to the control group in which all animals had developed severe ...

1989-10-01

162

British Library Electronic Table of Contents (United Kingdom)

Vaccine-mediated prevention of primary HIV-1 infection at the heterosexual mucosal portal of entry may be facilitated by highly optimised formulations or drug delivery devices for intravaginal (i.vag) immunization. Previously we described hydroxyethylcellulose (HEC)-based rheologically structured gel vehicles (RSVs) for vaginal immunization of an HIV-1 vaccine candidate, a soluble recombinant trimeric HIV-1 clade-C envelope glycoprotein designated CN54gp140. Here we investigated the efficacy of lyophilized solid dosage formulations (LSDFs) for prolonging antigen stability and as i.vag delivery modalities. LSDFs were designed and developed that upon i.vag administration they would reconstitute with the imbibing of vaginal fluid to mucoadhesive, site-retentive semi-solids. Mice were immunize...

2011-01-01

163

Water-Soluble Prodrug of Anti-Microtubule Agent Plinabulin: Effective Strategy with Click Chemistry.

Testing the Right Question Project (RQP) Health Education Strategy in a Mental Health Setting

PMID:21956869

2011-09-29

164

Studies on Vegetation for Ecological Restoration of Salt Marshes in Saemangeum Reclaimed Land - Germination Strategies and Character of Halophytes -

Diagnosis, Psychiatric

2010-10-08

165

Strategies of Avoidance - Value Chain Reactions in the Durban Clothing Industry

Full Text Available

2009-04-01

166

Norwegian Open Research Archives (NORA)

Full Text Available

167

Security Considerations For Network-Centric Weapon ...

Novel strategy for isolating suppressors of meiosis-deficient mutants and its application for isolating the bcy1 suppressor

... strategies. Computer and network security deals with cryptography, authentication, and attacks on software. Information ...

2009-09-01

168

Multi-state control strategy of starting for a wet friction clutch via a fuzzy logic algorithm

Full Text Available

1997-03-01

169

Improving Low-Reading Ages in the Secondary School Practical Strategies for Learning Support

Full Text Available

170

Continuous Strategy Development for Effects-Based ...

Improving Low-Reading Ages in the Secondary School

2004-01-01

171

Construction EC Strategy Model and Improving Fields for Global EC Transition

... BAE Systems Advanced Information Technologies, Inc. APPROVED FOR PUBLIC RELEASE; DISTRIBUTION UNLIMITED. ...

2006-02-01

172

Climate change adaptation in coastal zones: Improving decision-making to support management strategies

Full Text Available

2011-04-01

173

A Study on Stakeholders' Strategies toward IMO International Convention for Environmentally Sound Ship Recycling

No abstract prepared.

2009-02-01

174

Use of boron waste as an additive in red bricks

Full Text Available

2009-06-01

175

Text Mining Classification, Clustering, and Applications

In boron mining and processing operations, large amounts of clay containing tailings have to be discarded. Being rich in boron, the tailings do not only cause economical loss but also pose serious environmental problems. Large areas have to be allocated for waste disposal. In order to alleviate this problem, the possibility of using clayey tailings from a borax concentrator in red brick manufacturing was investigated. Up to 30% by weight tailings addition was found to improve the brick quality.

176

Energy and CO{sub 2eq} analysis of the agricultural phase in the sunflower biodiesel chain

An extension of data mining, text mining involves the extraction of information and knowledge from unstructured text. This constantly evolving field is increasingly used by major corporations, such as Google, Yahoo, and Microsoft. Featuring contributions from leading researchers in the field, this book provides a detailed overview of text mining theory, applications, and visualization. The theory section discusses text mining, information retrieval, latent semantic analysis, pagerank, latent Dirichlet allocation, and probabilistic relational models. In the section on text mining applications,

2009-01-01

177

Translation products of pre-S(1), pre-S(2) regions and the S gene of hepatitis B virus: susceptibility of their antigenic activities to treatment with heat, urea formalin or pepsin

The suitability of the sunflower for biodiesel production was discussed in terms of the reference values on carbon dioxide equivalents (CO{sub 2eq}) emissions for every phase of the biofuels chain as indicated in the European Union (EU) Directive on renewable energies. A life cycle analysis performed on the agricultural phase of the sunflower showed that CO{sub 2eq} emissions from the cultivation phase exceeded the EU reference value. This paper highlighted the relevance of allocation methods to spread out energy consumption and CO{sub 2eq} emissions among sunflower biodiesel and oilcake. Allocation was made according to the principles of mass content, energy content and the economic value of co-products. The CO{sub 2eq} reductions obtained with the 3 methods were approximately 60, 50 and 25 per cent, respectively when compared to a case without allocation. Since these methods did not distinguish the different functionality ...

2010-07-01

178

Serum and salivary responses to oral tetravalent reassortant rotavirus vaccine in newborns.

Hepatitis B subviral particles, purified from plasma of asymptomatic carriers seropositive for hepatitis B e antigen, were treated with various conditions reported for the processing of vaccines. Thereafter,...Full Text Available

1986-12-01

179

Safety and immunogenicity of ERA strain of rabies virus propagated in a BHK-21 cell line.

Serum and salivary responses of 95 infants to either a standard (4 x 10(4) plaque-forming units (PFU), 47 neonates) or a high dose (4 x 10(5) PFU, 48 neonates) of tetravalent reassortant rhesus rotavirus...Full Text Available

1993-05-01

180

Recruitment of intestinal CD45RA+ and CD45RC+ cells induced by a candidate oral vaccine against porcine post-weaning colibacillosis.

The ERA strain of rabies virus was propagated in a baby hamster kidney cell line (BHK-21/C13). The viral titer was 10(1.8) tissue culture infective doses (TCID) higher than that of commercial ERA vaccine....Full Text Available

1989-10-01

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181

Murine antibody response to oral infection with live aroA recombinant Salmonella dublin vaccine strains expressing filamentous hemagglutinin antigen from Bordetella pertussis.

To assess the influence of a live attenuated oral vaccine against porcine post-weaning colibacillosis (PWC) induced by enterotoxigenic Escherichia coli (ETEC) on mucosal lymphoid cell CD45 isoforms expression, experimental group of weaned pigs (n=6) was immunized orally with F4ac+ non-ETEC strain (day 0) and challenged with F4ac+ ETEC strain 7 days latter. Non-immunized ETEC-infected pigs (n=6) served as control. All pigs were killed on post-challenge day 7. The small intestine was excised for isolation of jejunal lamina propria (JLP) and ileal Peyer's patch (IPP) lymphocytes and immunohistochemical studies. The results obtained by immunophenotyping of isolated cells show that the proportion of CD45RA+ and CD45RC+ JLP, but not IPP, cells were higher in the non-ETEC-immunized ETEC-infected pigs versus non-immunized infected. Additionally, while CD45RA+ JLP cells increased only slightly, the expression of CD45RC isoform on the JLP cells was significantly higher ...

2002-07-01

182

Invasiveness and persistence of Salmonella enteritidis, Salmonella typhimurium, and a genetically defined S. enteritidis aroA strain in young chickens.

Two plasmids which express either nearly intact or truncated filamentous hemagglutinin (FHA) from Bordetella pertussis and which are marked with a tetracycline resistance (Tcr) gene were transformed into Salmonella dublin SL1438, an aroA deletion mutant intended for use as an attenuated oral vaccine against salmonellosis. These S. dublin recombinants, when fed to mice, induced serum immunoglobulin, immunoglobulin M (IgM), and sometimes IgA antibody responses to FHA and S. dublin. In addition, IgA antibodies against FHA were found in gut wash fluids. S. dublin carrying pDB2300, a multicopy plasmid encoding truncated FHA protein, induced a better antibody response than did S. dublin carrying pDB2000, a low-copy-number plasmid encoding full-sized FHA. Administration of tetracycline to mice enhanced the stability of recombinant plasmids, and tetracycline-treated mice developed higher anti-FHA titers. Although neither strain examined is suitable for use in a human oral ...

1990-08-01

183

Interferon-? expressed by a rabies virus-based HIV-1 vaccine vector serves as a molecular adjuvant and decreases pathogenicity

Newly hatched chicks were dosed orally with a Salmonella typhimurium wild-type strain, an S. enteritidis wild-type strain, and a genetically defined S. enteritidis aroA vaccine candidate, strain CVL30....Full Text Available

1994-11-01

184

Induction of Antibody Responses to African Horse Sickness Virus (AHSV) in Ponies after Vaccination with Recombinant Modified Vaccinia Ankara (MVA)

Type I interferon is important in anti-viral responses and in coordinating the innate immune response. Here we explore the use of interferon-β to adjuvant the response to a rabies virus...Full Text Available

2008-12-20

185

Helper T-Cell Epitopes Encoded by the Babesia bigemina rap-1 Gene Family in the Constant and Variant Domains Are Conserved among Parasite Strains

BackgroundAfrican horse sickness virus (AHSV) causes a non-contagious, infectious disease in equids, with mortality rates that can exceed 90% in susceptible horse populations....Full Text Available

186

Differential Specificity and Immunogenicity of Adenovirus Type 5 Neutralizing Antibodies Elicited by Natural Infection or Immunization?

Among important candidates for babesial vaccines are apical complex proteins, including rhoptry-associated protein 1 (RAP-1) from Babesia bovis and B. bigemina, which...Full Text Available

1998-04-01

187

A progress for the health of south countries. The solar refrigerator; Un progres pour la sante dans les pays du Sud. Le refrigerateur solaire

A recent clinical trial of a T-cell-based AIDS vaccine delivered with recombinant adenovirus type 5 (rAd5) vectors showed no efficacy in lowering viral load and was associated with increased risk of...Full Text Available

2010-01-01

188

How Do Police Respond to Stalking? An Examination of the Risk Management Strategies and Tactics Used in a Specialized Anti-Stalking Law Enforcement Unit

In order to conserve vaccines in hot countries a solar refrigerator has been made by a French university. It is a photothermal refrigerator without batteries. It uses two gases: ammonia and calcium chloride. The refrigerator is autonomous and can work eleven days without sun. (N.C.)

1998-05-01

189

British Library Electronic Table of Contents (United Kingdom)

How do police respond to and manage complaints of stalking? To answer this question, we conducted a 3-phase study. First, we reviewed the literature to identify risk management tactics used to combat stalking. Second, we asked a group of police officers to review those tactics for completeness and group them into categories reflecting more general risk management strategies. The result was 22 categories of strategies. Finally, we used qualitative methods to evaluate the files of 32 cases referred to the specialized anti-stalking unit of a metropolitan police department. We coded specific risk management tactics and strategies used by police. Results indicated that a median number of 19 specific tactics from 7 general strategies were used to manage risk. Also, the implementation of strategi...

2011-01-01

190

Validation of the treatment identification strategy of the HEDIS addiction quality measures: concordance with medical record review

Renewable energy and the ODA energy efficient strategy

BackgroundStrategies to accurately identify the occurrence of specific health care events in administrative data is central to many quality improvement and research efforts. Many...Full Text Available

191

Randomized controlled trial comparing four strategies for delivering e-curriculum to health care professionals [ISRCTN88148532

The energy strategy of the UK Overseas Development Administration is outlined with specific emphasis on energy efficiency and renewable energies. Based on 29 case studies concerning projects and programmes in both developed and developing countries, critical success factors for renewable energy projects are identified. UK)

1995-12-31

192

Hydrogen bonding and perhalometallate ions: A supramolecular synthetic strategy for new inorganic materials

BackgroundInternet education is increasingly provided to health professionals, but little is known about the most effective strategies for delivering the content. The purpose of...Full Text Available

193

Department of Energy low-level waste management strategy

A synthetic strategy for constructing ionic hydrogen-bonded materials by combining perhalometallate anions with cations able to serve as hydrogen bond donors is presented. The approach is based on identification...Full Text Available

2002-04-16

194

Clinical Strategy for the Management of Solid Pseudopapillary Tumor of the Pancreas: Aggressive or Less?

The DOE strategy recognizes that public perception of low-level waste management practices is not positive. Actions are included that are aimed at opening the system to the public. A better informed public will be able to better assess the performance of the low-level waste management system.

1980-01-01

195

Assessment during aggressive contests between male jumping spiders

Objective: To further delineate the clinicopathological and radiological features of solid pseudopapillary tumor (SPT) of the pancreas and summarize the surgical therapy strategy for this tumor. Methods:...Full Text Available

196

Why Strategy is Difficult

Assessment strategies are an important component in game theoretical models of contests. Strategies can be either based on one’s own abilities (self assessment) or on the relative abilities...Full Text Available

2008-09-01

197

The Way Ahead: CENTCOM's New Strategy for Theater ...

... In the Arabian Gulf region, environmental security efforts complement USCENTCOM's Cooperative Defense Initiative (CDI) activities, and offer a ...

2011-05-13

198

The Sustainment Management Support Project

... The CENTCOM AOR encompasses the world's most energy-rich region, with the Arabian Gulf region and Central Asia together ...

2010-05-03

199

Robust distributed model predictive control: A review and recent developments

... due to the evolving nature of the Strategy Maps and the changing priority roles, it was decided not to link the SMSP directly with any Strategic Plans. ...

2010-09-01

200

British Library Electronic Table of Contents (United Kingdom)

Abstract This study presents a review of distributed model predictive control (DMPC) strategies followed by recent studies conducted by the authors on the robustness of these strategies to model errors and a summary of future challenges in this area. The review identifies three key challenges for the successful application of DMPC: (i) the selection of optimal control structure for DMPC; (ii) the choice of a suitable coordination strategy among the controllers; and (iii) the robustness of DMPC strategies to model errors. Then, the study summarises recent developments related to the robustness of unconstrained and constrained DMPC algorithms. For the unconstrained case, a methodology that is based on the calculation of a performance index is proposed to balance the trade-off between perform...

2011-01-01

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201

Functional strategies of the hindlimb muscles in the mouse deer

Energy control strategy for a hybrid electric vehicle

... were larger in TFLM, BFM, QFM, PM and TSM in the mouse deer than in the two ... ...

202

CMS Silicon Strip Tracker Performance

An energy control strategy (10) for a hybrid electric vehicle that controls an electric motor during bleed and charge modes of operation. The control strategy (10) establishes (12) a value of the power level at which the battery is to be charged. The power level is used to calculate (14) the torque to be commanded to the electric motor. The strategy (10) of the present invention identifies a transition region (22) for the electric motor's operation that is bounded by upper and lower speed limits. According to the present invention, the desired torque is calculated by applying equations to the regions before, during and after the transition region (22), the equations being a function of the power level and the predetermined limits and boundaries.

2002-08-27

203

Battery Thermal Management System Design Modeling

In this paper we describe the reconstruction strategies, the calibration procedures and the detector performance results from the latest CMS operation.

2011-01-01

204

Symbol Error Rates of Maximum-Likelihood Detector: Convex/Concave Behavior and Applications

Looks at the impact of cooling strategies with air and both direct and indirect liquid cooling for battery thermal management.

2006-11-01

205

Resuscitation and monitoring in gastrointestinal bleeding

Convexity/concavity properties of symbol error rates (SER) of the maximum likelihood detector operating in the AWGN channel (non-fading and fading) are studied. Generic conditions are identified under which the SER is a convex/concave function of the SNR. Universal bounds for the SER 1st and 2nd derivatives are obtained, which hold for arbitrary constellations and are tight for some of them. Applications of the results are discussed, which include optimum power allocation in spatial multiplexing systems, optimum power/time sharing to decrease or increase (jamming problem) error rate, and implication for fading channels.

2007-01-01

206

British Library Electronic Table of Contents (United Kingdom)

Introduction Gastrointestinal bleeding is a common life-threatening problem, causing significant mortality, costs and resource allocation. Its management requires a dynamic multidisciplinary approach that directs diagnostic and therapeutic priorities appropriately. Materials and methods Articles published within the past 15 years, related to gastrointestinal bleeding, were reviewed through MEDLINE search, in addition to current guidelines and standards. Results Decisions of ICU admission and blood transfusion must be individualized based on the extent of bleeding, hemodynamic profile and comorbidities of the patient and the risk of rebleeding. A secure airway may be required to optimize oxygenation and to prevent aspiration. Doses of induction agents must be reduced due to the changes in v...

2011-01-01

207

Method for design of working face operation in black coal mines

Hazard Evaluation for the Saltwell Chempump and a Saltwell Centrifugal Pump Design using Service Water for Lubrication and Cooling

Methods are discussed for optimization of organizational model of longwall mining. Operations at a working face, their duration, number of miners, miner qualifications are analyzed. The so-called method for allocation of heteregeneous resources is used. Using the method optimum organizational models of working faces are constructed. The models consider working conditions, coal output, personnel, miner qualifications, duration of various operations and of idletime, and safety regulations. A computer code developed by the author for optimizing organizational models of longwall mining is described. 9 refs.

1983-01-01

208

Application of relationship marketing and management: a large contractor case study

This report documents results of a preliminary hazard analysis (PHA) covering the existing Crane Chempump and the new salt well pumping design. Three hazardous conditions were identified for the Chempump and ten hazardous conditions were identified for the new salt well pump design. This report also presents the results of the control decision/allocation process. A backflow preventer and associated limiting condition for operation were assigned to one hazardous condition with the new design.

2000-11-16

209

British Library Electronic Table of Contents (United Kingdom)

Marketing-led enterprise change management initiated by a major UK contractor is explored in this paper as a contrast to procurement-led changes to projects driven by clients. Procurement-led initiatives try to induce changes to behaviour through market governance. Relationship marketing and management proactively change organizational behaviour, the enterprise taking responsibility for its own destiny. Investment and resource allocation, and organizational behaviour have posed constraints, particularly concerning service continuity in construction. Overcoming these constraints offers opportunities for delivering service improvements and adding value for clients and yielding further increases in repeat business and increasing profitability. Relationship marketing is the conceptual starting...

2009-01-01

210

Development in harmony with our environment : final report of the Manitoba Round Table on Environment and the Economy 1988-1997

Physiological responses of Pinus sylvestris to changing carbon dioxide and ozone concentrations

This final report of the Manitoba Round Table on Environment and Economy (MRTEE) chronicles its history, objectives, accomplishments and ongoing challenges from 1988-1997. MRTEE`s mandate was to promote environmentally sustainable economic development in Manitoba through policies and programs that combine environmental concerns with economic decisions. The seven main objectives of the MRTEE were: (1) the implementation of a sustainable development strategy for Manitoba, (2) the design of a communications program on environment-economy integration and an action plan to upgrade environmental education, (3) implementation of market-driven and incentive programs to promote environmental protection by business, agriculture and resource users, (4) implementation of sustainable development within the public sector, (5) encouragement of individual businesses, farms and resource users to adopt codes of environmental practice, (6) encouragement of specific projects that ...

1998-12-01

211

Clinical aspects of Marburg hemorrhagic fever

The objective of this research is to study the effects of elevated ozone, carbon dioxide and their combination on ultrastructural, physiological and biochemical responses of Scots pine needles and how these effects are reflected to photosynthesis, carbohydrate and nutrient allocation and finally to shoot and root growth of trees. In addition the interactions of the studied trees and mycorrhizal fungi as well as insect herbivores are studied. The exposures have been running only for two growing periods and it seems necessary to continue the experiment over the third growing season in 1996. Since the analyses are partially incomplete, only preliminary conclusions are possible at the moment. The slightly increased shoot growth and needle width and increased amount of starch in chloroplasts point to the slight stimulating effect of elevated CO{sub 2} among the chamber treatments. Altogether the growth of the seedlings was best in the chamberless treatment indicating a ...

1996-12-31

212

British Library Electronic Table of Contents (United Kingdom)

Marburg virus belongs to the genus Marburgvirus in the family Filoviridae and causes a severe hemorrhagic fever, known as Marburg hemorrhagic fever (MHF), in both humans and nonhuman primates. Similar to the more widely known Ebola hemorrhagic fever, MHF is characterized by systemic viral replication, immunosuppression and abnormal inflammatory responses. These pathological features of the disease contribute to a number of systemic dysfunctions including hemorrhages, edema, coagulation abnormalities and, ultimately, multiorgan failure and shock, often resulting in death. A detailed understanding of the pathological processes that lead to this devastating disease remains elusive, a fact that contributes to the lack of licensed vaccines or effective therapeutics. This article will review the...

2011-01-01

213

Development of a central information system, communication system and cooperation system for the German Strategy for Adaptation to Climate Change (IKK-DAS); Aufbau eines zentralen Informations-, Kommunikations- und Kooperationssystems fuer die Deutsche Anpassungsstrategie an den Klimawandel (IKK-DAS)

Urinary tract infection: diabetic women's strategies for prevention.

The research project started in April, 2008 before adoption of the cabinet report of the Federal Government to the German strategy for Adaptation to Climate Change. The German Strategy for Adaptation emphasizes the meaning of information about requirements for adaptation and the active involvement of all social groups in the other process of the strategy. For this the research project has made concrete proposals for the information, communication and participation of social groups. These proposals are based in the essentials on an interest analysis about interviews with stakeholders and the economy to their demands and expectations to the German strategy for Adaptation. Besides we have researched international examples for the adaptation to the climate change for the public relations. For the interactive development of the Internet platform www.anpassung.net concrete proposals were developed. (orig.)

2010-03-15

214

Hybrid ventilation. Control strategies for hybrid ventilation, consequences for air quality, thermal comfort and energy use; Hybrid ventilasjon

Urinary tract infection (UTI) is a common problem in the female population. Women with diabetes mellitus are possibly at a higher risk. The usual medical therapy for UTI is antibiotic treatment. The aim of this study is to explore strategies employed by diabetic women for prevention and self-treatment of UTI. Forty-two women with diabetes mellitus who had experienced at least one episode of UTI in the last six months were included. Data collection included background information, questions about prevention and self-treatment strategies and a clinical examination to measure maximal urine flow, residual urine, a blood test evaluating diabetic control (HbA1c) and a urine test strip for determination of glucose, leucocytes, nitrite, blood, protein and pH. Thirty-five participants (83.3%) reported changes in daily routines like 'always keeping warm', 'increased fluid intake', 'good personal hygiene' as prevention strategies. ...

215

Focus on the customer, the novel approach of energy companies. Terms and definitions, instruments, suitability assessment of key-account management strategies. Kundenorientierung bei EVU. Begriff-Instrumente-Eignung

This article deals with the need for control strategies and control systems in buildings with hybrid ventilation. In this respect, control strategies are methods of keeping certain parameters like temperature, air quality etc within specified limits. A control system is automatic and includes sensors, motors, dampers etc. The article also discusses consequences with respect to thermal comfort, air quality and energy use following selection of control parameters for controlling air masses.

2001-07-01

216

A New Fuzzy MCDM Framework to Evaluate E-Government Security Strategy

With increasing liberalization of the energy sector, German suppliers of line-transmitted energy find themselves in an utterly changed sales environment, forcing companies and utilities to elaborate for the first time management policies and strategies that will ensure loyalty of their present customers, and help to solicit new customers. The article here explains some major terms and instruments used in designing key-account management strategies, as well as general procedures for suitability assessment. (orig/CB)

1999-06-01

217

The Financial War on Terrorism: Grading US Strategy for ...

Ensuring security of e-government applications and infrastructures is crucial to maintain trust among stakeholders to store, process and exchange information over the e-government systems. Due to dynamic and continuous threats on e-government information security, policy makers need to perform evaluation on existing information security strategy as to deliver trusted e-government services. This paper presents an information security evaluation framework based on new fuzzy multi criteria decision making (MCDM) to help policy makers conduct comprehensive assessment of e-government security strategy.

2010-01-01

218

The Economic Strategy for German Unification

... that operated in Pakistan, Dubai, and throughout the Middle East ... identifies 'funds' as one of eight major terrorist ... techniques, and procedures (TTP). ...

2006-04-15

219

Strategic Communication: A Department of Defense Approach

... PERSONAL AUTHOR(S) ROY A. BROOKS, LTC i3a. ... gave the impression of an immediate increase in the standard ... high rate by German standards. ...

1993-02-19

220

Saddam Hussein's Grand Strategy During the Iran-Iraq War

... development of SC policy within DOD, because it describes the necessary link between DOD ... strategy convolutes USG efforts to develop SC policy. ...

2007-03-28

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221

Ras activation of genes: Mob-1 as a model.

... power in the Arabian Gulf region with Iraq emerging as the new champion of the Arab world. These two political objectives ...

2011-05-13

222

Pseudomonas aeruginosa Virulence and Therapy: Evolving Translational Strategies

The ras oncogenes function by indirectly controlling expression of a subset of yet-undefined genes that are crucial for cell growth and differentiation. In a differential display strategy, numerous...Full Text Available

1994-12-20

223

Proteomic strategies in multiple sclerosis and its animal models

Structured abstractObjectiveAlthough most reviews of Pseudomonas aeruginosa therapeutics focus on antibiotics currently in use or...Full Text Available

2009-05-01

224

Probiotic Bacteria as Biological Control Agents in Aquaculture

The early and precise diagnosis, the prognosis, and the clinical management of multiple sclerosis, remain a considerable challenge. In recent years, the development of novel and powerful proteomic...Full Text Available

2007-10-16

225

Performance-Based Life Cycle Product Support Strategies ...

There is an urgent need in aquaculture to develop microbial control strategies, since disease outbreaks are recognized as important constraints to aquaculture production and trade and since the development...Full Text Available

2000-12-01

226

Pacification: The Overall Strategy in South Vietnam

... The C-130J is a modification of the C-130H, undertaken by Lockheed Martin Aeronautics Corporation (LMAC) as a private ven- ture, with intended ...

2010-10-01

227

On strategies for imbalanced text classification using SVM: A comparative study

... implementation." 4 1 Factors Affecting Rural Construction. Two new factors profoundly modify today's pacification equa- tion. ...

1966-04-22

228

British Library Electronic Table of Contents (United Kingdom)

Many real-world text classification tasks involve imbalanced training examples. The strategies proposed to address the imbalanced classification (e.g., resampling, instance weighting), however, have not been systematically evaluated in the text domain. In this paper, we conduct a comparative study on the effectiveness of these strategies in the context of imbalanced text classification using Support Vector Machines (SVM) classifier. SVM is the interest in this study for its good classification accuracy reported in many text classification tasks. We propose a taxonomy to organize all proposed strategies following the training and the test phases in text classification tasks. Based on the taxonomy, we survey the methods proposed to address the imbalanced classification. Among them, 10 common...

2009-01-01

229

Neurotoxic and pharmacokinetic responses to trichloroethylene as a function of exposure scenario.

National Military Strategy to Combat Weapons of Mass ...

Strategies are needed for assessing the risks of exposures to airborne toxicants that vary over concentrations and durations. The goal of this project was to describe the relationship between the concentration...Full Text Available

2000-05-01

230

Informational Element of Power: The Role of Public Diplomacy ...

... and regional land, sea, air, and space-based systems, and ... means of delivery of weapons where such ... a separable and divisible part of the weapon. ...

2006-02-13

231

How Can Political Campaign Strategy be Adopted to Support ...

... 26 Department of National Security and Strategy, Elements of National Power Model or MID-LIFE Model, US Army War College, 2004. 27 Ibid. ...

2005-03-18

232

... WHS- Washington Headquarters Service ... present a framework based on political campaigns theory for both the Joint Task Force Commander down ...

2010-10-27

233

Greening EPA | US EPA

Geothermal materials program: strategy. Final report

strives to reduce our "environmental footprint" in the following areas: EPA Facilities Energy Conservation Requirements | Goals and Strategies | Results | Reports Green Power...

2011-08-16

234

Development of a 2-Aza-Cope-[3+2] Dipolar Cycloaddition Strategy for the Synthesis of Quaternary Proline Scaffolds

The following topics are discussed: program goal and objectives, program organization, and program status. Current program projects are described. (MHR)

1980-10-01

235

Course, Curriculum, and Laboratory Improvement (CCLI)

A one-pot multicomponent procedure for the synthesis of highly functionalized pyrrolidine rings through a domino...Full Text Available

2010-09-03

236

Clinical Recovery in First-Episode Psychosis

... teaching and learning; Creating learning materials and teaching strategies; Developing faculty ... achieve educational innovations. Educational Materials Development (EMD): A project under the former ...

237

Cardioprotection conferred by exercise training is blunted by blockade of the opioid system

Introduction: Generally agreed outcome criteria in psychosis are required to evaluate the effectiveness of new treatment strategies. The aim of this study is to explore clinical recovery...Full Text Available

2009-03-01

238

Breeding strategies with poplars in Europe

OBJECTIVES:To investigate the effect of opioid receptor blockade on the myocardial protection conferred by chronic exercise and to compare exercise training with different strategies...Full Text Available

2011-01-01

239

A task-based usage strategy for control centre wall displays

Poplar breeding in Europe is in a more advanced state than breeding programmes of other species. In Europe, poplars are part of the scenery and are integrated in the economy. Traditionally poplar stands are established in lowland areas. But an increasing interest in their use moved them to upland sites. Poplar uses are multiple: lumber, industrial wood, wind-breaks and landscape plantations, etc. Selection characteristics are classified in different groups: vegetative propagation ability, vigor, adaptation to sites and climate, resistance to diseases and insect pests, wood quality, and coppicing ability. Strategies have improved with time. The most efficient strategies for the long term involve constitution of base populations, selection of parents for intra- and interspecific hybridizations, selection within the progenies, and vegetative propagation. Short term strategies are also applied simultaneously. Advanced breeding ...

1984-01-01

240

A Call for an Official Naval Doctrine

This paper summarizes the findings from an exploratory definition of a usage strategy for multiple control centre wall displays in CANDU nuclear power plants. Wall displays are defined as large sized, vertically oriented display surfaces that may be positioned in various locations about a control room to support user information needs. The paper begins by discussing the need for a usage strategy for all control room information resources, and then reviews the history in wall display implementation and usage in nuclear power plant control rooms. The balance of the paper discusses the approach used in characterization and review of control room task information needs and definition of a wall display usage strategy. The paper concludes by outlining some of the possible impacts on future control room design and operations that the introduction of wall displays may imply. (author)

2005-07-01

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241

Resource-loaded planning for ALICE

... 1. Major Grover E. Myers, Aerospace Power: The Case for Indivisible ... 19. Admiral James D. Watkins, The Maritime Strategy (Annapolis: US Naval ...

1992-02-13

242

Northeast coal study: resource planning framework, resource development status report. 3 Vols

The ALICE experimental area management team faces various challenges when it comes to sharing scarce resources, indispensable to any efficient installation in a category one worksite. Space, cranes, jigs, and personnel with key competences have to be carefully allocated to activities so as to avoid slowing down work progress. To this intent, a resource loaded planning has been developed that allows highlighting coactivities and prioritizing critical tasks. It uses the built-in capabilities of Microsoft Project. The use of this scheduling tool leads to a more efficient use of time and a safer work environment. The installation sequence resulting from this schedule is presented in this paper. The first part of the sequence focuses on the revision of the coils in the SX2 building. The dipole has then to be installed in the RB26 side of the UX25 cavern. This complex and resource intensive activity has to be performed in parallel with the services installation inside ...

2005-01-01

243

New models needed to manage gas supply, APPrO conference hears

The objective of this study was to provide a framework for land use and resource allocation decisions in the Northeast Coal Block of British Columbia. The area was divided into a number of sites, and information gathered in two main areas, 1) status of the resource base, and 2) resource management/planning/development. A map and physical description of each site is provided as well as such information as - air quality, soils, vegetation, water resources, petroleum and natural gas resources, coal resources, and gravel resources, agricultural resources, timber resources, fisheries and wildlife resources, recreatational and aesthetic (visual) resources. The appendix volume provides a summary of the institutional management framework and approval procedures for all significant resource sectors. Provincial legislation and government acts are identified.

1982-01-01

244

Male meadow voles respond differently to risk and intensity of sperm competition

Details of a 1 day conference designed to create more efficient interactions between the gas supply and electricity systems in Ontario and new models for gas supply and the electricity system were presented. Market efficiency, generators' perspectives on critical gas issues, an overview of the North American gas and an outline of issues concerning Ontario were discussed. A natural gas industry forecast and issues concerning marketers and producers were presented. The terms on which gas is bought and sold were discussed. Regulatory tools, cost allocation and issues relating to unbundling were also presented. Infrastructure needs were reviewed, as well as basic market structures. It was suggested that appropriate commercial service options need to be developed and approved, including cross-utility services.

2005-08-01

245

British Library Electronic Table of Contents (United Kingdom)

There are 2 models of male adjustment of sperm investment in the ejaculate in relation to sperm competition. The "risk model" predicts that as "risk" of sperm competition increases, sperm investment also increases. This prediction has been supported in many species, including mammals. The "intensity model" involves the number of competing males copulating with the same female and predicts that males will allocate the highest sperm investment at low sperm competition intensity (SCI) and then decreasing sperm investments as SCI increases. Two alternative outcomes are that sperm investment is unaffected by SCI and that sperm investment increases as SCI increases. There are studies supporting all 3 possible outcomes in relation to SCI but no data on mammals. The present paper presents the firs...

2006-01-01

246

Laparoscopic sigmoid resection for diverticular disease has no advantages over open approach: midterm results of a randomized controlled trial

British Library Electronic Table of Contents (United Kingdom)

Purpose Elective laparoscopic sigmoid resection (LSR) for symptomatic diverticular disease is supposed to have significant short-term advantages compared to open surgery (open sigmoid resection (OSR)). This opinion is rather based on inferences from trials on colonic resections for malignant diseases or minor laparoscopic surgery. This randomized controlled trial was conducted to compare quality of life as well as morbidity and clinical outcome after LSR vs. OSR following a midterm follow-up period. Methods Patients presenting with a symptomatic sigmoid diverticular disease stage II/III (Stock/Hansen) were randomly allocated to LSR or OSR in a prospective multicenter trial. Endpoints included the quality of life assessed with a standardized questionnaire, postoperative mortality, and compl...

2011-01-01

247

Irreversible Performance of a Quantum Harmonic Heat Engine

Implementation of a hybrid power system stabilizer

The unavoidable irreversible losses of power in a heat engine are found to be of quantum origin. Following thermodynamic tradition a model quantum heat engine operating by the Otto cycle is analyzed. The working medium of the model is composed of an ensemble of harmonic oscillators. A link is established between the quantum observables and thermodynamical variables based on the concept of canonical invariance. These quantum variables are sufficient to determine the state of the system and with it all thermodynamical variables. Conditions for optimal work, power and entropy production show that maximum power is a compromise between the quasistatic limit of adiabatic following on the compression and expansion branches and a sudden limit of very short time allocation to these branches. At high temperatures and quasistatic operating conditions the efficiency at maximum power coincides with the endoreversible result. The optimal compression ratio varies from the square ...

2006-01-01

248

Impacts on Competitiveness from EU ETS. An analysis of the Dutch Industry

Dynamic stability enhancement of composite mode oscillations of interconnected power systems by means of a hybrid power system stabilizer is discussed here. The proposed Hybrid PSS is of a two-level structure composed of a local PSS for local mode and a global PSS for inter-area mode damping. Here, the input of the global stabilizer is the center of inertia speed deviation of slow-coherent generators. The paper is focused on the practical considerations in implementation of the proposed stabilizer. First, the optimum allocation of this stabilizer is discussed. The authors introduce an index of mode-input-assignability, by which the best sites of the stabilizer can be identified. Next, for practical applications, an estimation method for the approximation of the input of the global PSS is introduced. An approximated value of the center of inertia speed is obtained from a suitable combination of the rotor speed data of a few properly selected key generators.

1989-11-01

249

Free Time Management Contributes to Better Quality of Life: A Study of Undergraduate Students in Taiwan

The EU emissions trading scheme (ETS) was launched in 2005 to cap CO2 emissions from large industrial facilities and electricity producers. The European Commission is currently designing the post 2012 EU ETS, as outlined in COM(2008)16. Novel to this system is that a greater part of the rights will be auctioned. Auctioning in general assures a greater deal of efficiency compared to (certain types of) free allocation, lowers the administrative costs and prevents eventual windfall profits. However, auctioning also implies a potential loss of competitiveness for industry. If no international agreement on future climate policies is reached, firms may not be able to pass on the higher costs to their customers and may be faced with a loss in profitability and the threat of import substitution. In any emission trading scheme with an absolute cap, a relocation of production that is not covered by CO2 targets implies an increase in global CO2 emissions. This phenomenon has ...

2008-01-15

250

British Library Electronic Table of Contents (United Kingdom)

This study was designed to identify the relationship between free time management and quality of life, exploring whether the amount of free time or the way people using their free time relates to their quality of life. Data were collected from National Pingtung University of Science and Technology in Taiwan. Of the 500 questionnaires distribute, 403 usable questionnaires were received with an 81% response rate. The result has found a positive relationship between free time management and quality of life. Contrary to this, there was no significant relationship between time allocation and quality of life. Results might indicate that people who manage their free time well lead to better quality of life. Suggestions based on the observed relationship and directions for future researches were d...

2011-01-01

251

FY 1974 NPS independent development program

Effect of nonsteroidal anti-inflammatory drug plasters for knee osteoarthritis in Japanese: a randomized controlled trial

Thirteen summaries of exploratory development work carried out under a grant to the Naval Postgraduate School Research Foundation are included. This research was carried out in the areas of electrical engineering (slot lines; phase lock loops), aeronautics (aircraft survivability; composite materials for structures), material sciences (relation between high temperature compressive behavior and microstructure), mechanical engineering (fatigue life of ferrocement hull structures; flow fields), economics (hazardous employment incentives for DoD personnel), operations research (missile allocation modeling; combat dynamics; shipboard tank designs), oceanography breakwater construction effects on ecology), and physics (evaluation of an underwater acoustic parametric source).

1975-07-01

252

British Library Electronic Table of Contents (United Kingdom)

The objective of this study was to examine the effect of a nonsteroidal anti-inflammatory drug (NSAID) plaster for knee osteoarthritis among Japanese patients. An open-labeled, randomized, controlled, multiclinic trial was performed involving outpatient clinic groups. Two comparative groups?plaster NSAIDs and oral NSAIDs?were randomly allocated. The drugs used were limited to the current top three in both groups in Japan. Treatments were assessed after four?weeks and compared with the baseline scores. Outcomes were evaluated by two psychometric measures: Japanese knee osteoarthritis measure, and pain with the visual analogue scale. The total number of patients included in the final evaluation was 165 (87 for the plaster group and 78 for the oral group). Between these two groups there were ...

2010-01-01

253

Dynamic Adjustment of Irrigation Technology/Water Management in Western U.S. Agriculture: Toward a Sustainable Future

British Library Electronic Table of Contents (United Kingdom)

Changing water demands induced through climate change and a growing biofuel energy sector throughout the western States are expected to increase pressures on the present allocation mechanisms for an increasingly scarce resource, raising uncertainty about the sustainability of irrigated agriculture in the West. In this paper, we first present the policy motivation for examining continued producer adoption of water conserving irrigation production systems as a foundation for providing a sustainable future for western irrigated agriculture. Second, we summarize the historical transitions that help to define the adjustment path to increased sustainability for the sector. While western irrigated agriculture is on a path toward greater sustainability, evidence suggests that the sustainability go...

2010-01-01

254

Biomass production and relative competitiveness of a C3 legume and a C4 grass co-dominant in the semiarid Loess Plateau of China

British Library Electronic Table of Contents (United Kingdom)

Bothriochloa ischaemum L. and Lespedeza davurica (Laxm.) Schindl. are two co-dominant species of great importance in reducing soil and water loss and maintaining the distinctive natural scenery of the semiarid Loess Plateau of China. Our aim was to determine the growth and interspecific competition between these species under water stress to facilitate the prediction of community succession and guide the selection of appropriate methods of conservation and use in the area. A pot experiment was designed to investigate the effects of water stress and competition on biomass production and allocation, relative competitive ability and water use efficiency of the two species. Bothriochloa ischaemum (a C4 perennial herbaceous grass) was planted in the same pot with L. davurica (a C3 perennial leg...

2011-01-01

255

Advances in operations research in the oil and gas industry

A Novel Bid Optimizer for Sponsored Search Auctions based on Cooperative Game Theory

Various theories and examples of modelling, forecasting and optimization designing in the different parts of the petroleum and gas industries are presented, stochastic programming for long term planning in the refining industry, stochastic model for gasoline blending, feedstock optimization, location and sizing for offshore platforms, hydrocarbon exploration simulation rapid method, valuation of oil field development leases, economic models for petroleum allocation, models for oil supply market, trade embargo game theory, stochastic programming of gas contract portfolio management, scheduling transportation of oil and gas, strategic planning in an oil pipeline company, simulation of offshore oil terminal systems, hierarchical selection of oil and gas distribution systems.

1991-06-13

256

Science and Technology Review July/August 2010

In this paper, we propose a bid optimizer for sponsored keyword search auctions which leads to better retention of advertisers by yielding attractive utilities to the advertisers without decreasing the revenue to the search engine. The bid optimizer is positioned as a key value added tool the search engine provides to the advertisers. The proposed bid optimizer algorithm transforms the reported values of the advertisers for a keyword into a correlated bid profile using many ideas from cooperative game theory. The algorithm is based on a characteristic form game involving the search engine and the advertisers. Ideas from Nash bargaining theory are used in formulating the characteristic form game to provide for a fair share of surplus among the players involved. The algorithm then computes the nucleolus of the characteristic form game since we find that the nucleolus is an apt way of allocating the gains of cooperation among the search engine and the advertisers. The ...

2009-01-01

257

Novel Techniques and Their Wide Applications to Health Foods, Medical and Agricultural Biotechnology in Relation to Policy Making on Genetically Modified Crops and Foods

This issue has the following articles: (1) Deterrence with a Minimum Nuclear Stockpile - Commentary by Bruce T. Goodwin; (2) Enhancing Confidence in the Nation's Nuclear Stockpile - Livermore experts are participating in a national effort aimed at predicting how nuclear weapon materials and systems will likely change over time; (3) Narrowing Uncertainties - For climate modeling and many other fields, understanding uncertainty, or margin of error, is critical; (4) Insight into a Deadly Disease - Laboratory experiments reveal the pathogenesis of tularemia in host cells, bringing scientists closer to developing a vaccine for this debilitating disease. (5) Return to Rongelap - On the Rongelap Atoll, Livermore scientists are working to minimize radiological exposure for natives now living on or wishing to return to the islands.

2010-05-27

258

Methanogen community structure in the rumens of farmed sheep, cattle and red deer fed different diets

Selected applications of novel techniques in Agricultural Biotechnology, Health Food formulations and Medical Biotechnology are being reviewed with the aim of unraveling future developments and policy changes that are likely to open new markets for Biotechnology and prevent the shrinking or closing of existing ones. Amongst the selected novel techniques with applications in both Agricultural and Medical Biotechnology are: immobilized bacterial cells and enzymes, microencapsulation and liposome production, genetic manipulation of microorganisms, development of novel vaccines from plants, epigenomics of mammalian cells and organisms, and biocomputational tools for molecular modeling related to disease and Bioinformatics. Both fundamental and applied aspects of the emerging new techniques are being discussed in relation to their anticipated, marked impact on future markets and present policy changes that are needed for success in either Agricultural or Medical ...

2004-01-01

259

British Library Electronic Table of Contents (United Kingdom)

Abstract Development of inhibitors and vaccines that mitigate rumen-derived methane by targeting methanogens relies on knowledge of the methanogens present. We investigated the composition of archaeal communities in the rumens of farmed sheep (Ovis aries), cattle (Bos taurus) and red deer (Cervus elaphus) using denaturing gradient gel electrophoresis (DGGE) to generate fingerprints of archaeal 16S rRNA genes. The total archaeal communities were relatively constant across species and diets, and were less variable and less diverse than bacterial communities. There were diet- and ruminant-species-based differences in archaeal community structure, but the same dominant archaea were present in all rumens. These were members of three coherent clades: species related to Methanobrevibacter ruminan...

2011-01-01

260

Low cytotoxicity effect of dendrosome as an efficient carrier for rotavirus VP2 gene transferring into a human lung cell line

British Library Electronic Table of Contents (United Kingdom)

The efficiency of dendrosome (a gene porter) was assessed in transferring recombinant human rotavirus VP2 cDNA into A549, a human lung cell line. After gene transferring, transmission electron microscopy showed core-like particles (CLPs) formation in the transfected cells both with dendrosome and lipofectamine porters. In addition, western blotting analysis showed that the expression of VP2 gene was almost equal in the dendrosome and lipofectamine-transfected cells. Also, the cytotoxicity studies revealed that dendrosome had a lower cytotoxicity than lipofectamine. Therefore, our study may introduce dendrosome as a possible carrier for gene transferring into the human lung cell line, especially, for intranasally administration of DNA vaccines.

2009-01-01

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261

Global suppression of mitogen-activated ovine peripheral blood mononuclear cells by surface protein activity from Mycoplasma ovipneumoniae

British Library Electronic Table of Contents (United Kingdom)

Mycoplasma ovipneumoniae is associated with chronic non-progressive pneumonia of sheep and goats. As with many other mycoplasmas involved in animal diseases, protective immune responses have not been achieved with vaccines, even though antibody responses can be obtained. This study focuses on characterizing the interaction of M. ovipneumoniae with ovine PBMC using carboxy-fluorescein-succinimidyl-ester (CFSE) loading and flow cytometry to measure lymphoid cell division. M. ovipneumoniae induced a strong in vitro polyclonal suppression of CD4^+, CD8^+, and B blood lymphocyte subsets. The suppressive activity could be destroyed by heating to 60^oC, and partially impaired by formalin and binary ethyleneimine treatment that abolished its viability. The activity resided on the surface-exposed m...

2010-01-01

262

Estimates of quantitative genetic parameters of immunological traits in the chicken.

Diphtheria toxoid conformation in the context of its nanoencapsulation within liposomal particles sandwiched by chitosan

Three in vivo assays were used to measure the immunocompetence of chickens in two generations of a selection experiment. The obtained data were used to estimate the variance components for sire and dam for antibody production to Pasteurella multocida and Mycoplasma gallisepticum vaccines, for T-cell-mediated immunity evaluated by a phytohemagglutinin wing web assay, and for clearance of foreign particles from the circulatory system. Heritabilities of and genetic correlations among these immunological traits were calculated from the sire variance components. Heritability estimates of the immunological traits based on the sire component of variance ranged from .06 to .53, and genetic correlations among immunological traits were generally negative. PMID:1956847

1991-10-01

263

British Library Electronic Table of Contents (United Kingdom)

Chitosan (a?-(1-4)-amino-2-deoxy-b?-D-glucan) is a deacetylated form of chitin, a polysaccharide from crustacean shells. Its unique characteristics, such as positive charge, biodegradability, biocompatibility, nontoxicity, and rigid structure, make this macromolecule ideal for an oral vaccine delivery system. We prepared reverse-phase evaporation vesicles (REVs) sandwiched by chitosan (Chi) and polyvinylic alcohol (PVA). However, in this method, there are still some problems to be circumvented related to protein stabilization. During the inverted micelle phase of protein nanoencapsulation, hydrophobic interfaces are expanded, leading to interfacial adsorption, followed by protein unfolding and aggregation. Here, spectroscopic and immunological techniques were used to ascertain the effects ...

2011-01-01

264

Complete genome sequences of Brucella melitensis strains M28 and M5-90, with different virulence backgrounds.

Chloroquine for influenza prevention: a randomised, double-blind, placebo controlled trial

Brucella melitensis is a Gram-negative coccobacillus bacteria belonging to the Alphaproteobacteria subclass. It is an important zoonotic pathogen that causes brucellosis, a disease affecting sheep, cattle, and sometimes humans. The B. melitensis strain M5-90, a live attenuated vaccine cultured from the B. melitensis virulent strain M28, has been an effective tool to control brucellosis in goats and sheep in China. Here we report the complete genome sequences of B. melitensis M28 and M5-90, strains with different virulence backgrounds, which will serve as a valuable reference for future studies. PMID:21478357

2011-04-08

265

British Library Electronic Table of Contents (United Kingdom)

Background: Chloroquine has in-vitro activity against influenza and could be an ideal candidate for worldwide prevention of influenza in the period between onset of a pandemic with a virulent influenza strain and the development and widespread dissemination of an effective vaccine. We aimed to assess the efficacy of such an intervention. Methods: In this randomised, double-blind, placebo-controlled trial done at a single centre in Singapore, we randomly assigned (1:1) healthy adults to receive chloroquine phosphate (500 mg/day for 1 week, then once a week to complete 12 weeks) or matching placebo by use of a computer-generated randomisation list. Participants filled an online symptom diary every week, supplemented by daily diaries and self-administered nasal swabs when unwell. Haemagglutin...

2011-01-01

266

Antigenic characterization of phocine distemper virus causing mass mortality in 2002 and its relationship to other morbilliviruses

British Library Electronic Table of Contents (United Kingdom)

Summary The antigenic relationship between the phocine distemper virus (PDV) strain causing the epidemic in 2002 and the PDV strain of 1988, canine distemper virus from two dogs and one marten, and one measles virus strain was investigated in vivo and in vitro using monospecific polyclonal and monoclonal antibodies directed against five different proteins of canine or phocine distemper virus (N, P, M, F, H). Epitopic mapping revealed no difference between the PDV strains causing the epidemics in 1988 or 2002. However, the use of these antibodies allowed discrimination between different morbilliviruses including a vaccine strain of canine distemper virus. The major differences among the investigated morbilliviruses were found in the H protein.

2007-01-01

267

The safety concept of public gas supply in Germany

The Decommissioning of the Trino Nuclear Power Plant

The risk perception of the public consists of two components: the objectively factual component and the subjectively irrational component. The two strategies adopted by the German gas supply industry are the internal and the external communication strategy. Concepts and measures of accident precaution, registration and analysis of accident data (installation and operating errors, defects on flue systems, pipelines and valves, subsequent installation of gas appliances) are discussed. (R.P.)

1997-09-01

268

Melter Disposal Strategic Planning Document

Following a referendum in Italy in 1987, the four Nuclear Power Plants (NPPs) owned and operated by the state utility ENEL were closed. After closing the NPPs, ENEL selected a ''safestore'' decommissioning strategy; anticipating a safestore period of some 40-50 years. This approach was consistent with the funds collected during plant operation, and was reinforced by the lack of both a waste repository and a set of national free release limits for contaminated materials in Italy. During 1999, twin decisions were made to privatize ENEL and to transform the nuclear division into a separate subsidiary of the ENEL group. This group was renamed Sogin and during the following year, ownership of the company was transferred to the Italian Treasury. On formation, Sogin was asked by the Italian government to review the national decommissioning strategy. The objective of the review was to move from a safestore ...

2002-02-27

269

Export strategy for solar technology

This document describes the proposed strategy for disposal of spent and failed melters from the tank waste treatment plant to be built by the Office of River Protection at the Hanford site in Washington. It describes program management activities, disposal and transportation systems, leachate management, permitting, and safety authorization basis approvals needed to execute the strategy.

2000-09-25

270

Decision Strategy Research: Policy Support

EREC, the international umbrella organization, published last year a study on export strategies for renewable energy technologies. The 150-page document provides valuable information on key export markets and financial institutions, and presents the various branches' perspectives for the future. The following excerpts will whet your appetite for more. The complete study is available for download: www.erec-renewables.org (Eurees). (orig.)

2003-07-01

271

Current ventilation and air conditioning systems and strategies

The objective of SCK-CEN's R and D programme on decision strategy research are (1) to support and advise the Belgian authorities on specific problems concerning existing and potential hazards from exposure to ionising radiation, both in normal and emergency situations; (2) to perform research on relevant topics that might have an important impact on decision making related to nuclear applications, including social and economic sciences. Main achievements in this area in 1999 are described.

2000-07-01

272

Comparing two strategies of dynamic intensity modulated radiation therapy (dIMRT) with 3-dimensional conformal radiation therapy (3DCRT) in the hypofractionated treatment of high-risk prostate cancer

The report examines common ventilation and air conditioning systems and strategies for both domestic and commercial buildings; and covers issues such as energy conservation, indoor air quality and occupant comfort. Drawing data from many countries in Europe and the United States of America, various natural, mechanical and air conditioning systems were compared using criteria such as climate, level of occupant interaction, and level of system comfort. This classification system is evaluated and seen as a valuable framework for further research. (U.K.)

1994-02-01

273

Air quality analysis for the 1984 high altitude report to Congress: summary of results. Technical report

BackgroundTo compare two strategies of dynamic intensity modulated radiation therapy (dIMRT) with 3-dimensional conformal radiation therapy (3DCRT) in the setting of hypofractionated...Full Text Available

274

A new control strategy for tracking peak power in a wind or wave energy system

This report describes the data, assumptions, and methodology used in the air quality analysis for the 1984 High Altitude Report to Congress. Detailed descriptions of the strategies examined and the mobile source emission factors associated with each strategy are included in this report only by reference.

1981-04-01

275

Rents in the European power sector due to carbon trading

This paper proposes a novel control strategy for tracking peak power in a wind or wave energy system using a squirrel cage induction generator. It eliminates wind speed measurement or estimation and uses a simple scalar technique by exploiting the cubic nature of the power curve. The method works even when air velocity is varying dynamically. (author)

2009-06-15

276

Data Center Energy Benchmarking: Part 4 - Case Study on aComputer-testing Center (No. 21)

The European Union Emissions Trading Scheme (EU ETS) has imposed a price on the allowances for CO2 emissions of electricity companies. Integrating this allowance price into the price of electricity earns a rent for companies who have received these allowances for free. During Phase I, 2005-2007, rents corresponding to the aggregate value of allocated allowances amounted to roughly Euro 13 billion per year. However, due to the specific price-setting mechanism in electricity markets true rents were considerably higher. This is due to the fact that companies also that have not received any allowances gain additional infra-marginal rents to the extent that their variable costs are below the new market price after inclusion of the allowance price. Producers with low carbon emissions and low marginal costs thus also benefit substantially from carbon pricing. This paper develops a methodology to determine the specific interaction of the imposition of such a CO2 constraint ...

2010-08-01

277

Assessment of energy performance in the life-cycle of biogas production

The data center in this study had a total floor area of 8,580 square feet (ft{sup 2}) with one-foot raised-floors. It was a rack lab with 440 racks, and was located in a 208,240 ft{sup 2} multi-story office building in San Jose, California. Since the data center was used only for testing equipment, it was not configured as a critical facility in terms of electrical and cooling supply. It did not have a dedicated chiller system but served by the main building chiller plant and make-up air system. Additionally, it was served by a single electrical supply with no provision for backup power. The data center operated on a 24 hour per day, year-round cycle, and users had all hour full access to the data center facility. The study found that data center computer load accounted for 23% of the overall building electrical load, while the total power consumption attributable to the data center including allocated cooling load and lighting was 30% of the total facility load. ...

2007-08-01

278

Explicit representations of problem-solving strategies to support knowledge acquisition

Energy balances are analysed from a life-cycle perspective for biogas systems based on 8 different raw materials. The analysis is based on published data and relates to Swedish conditions. The results show that the energy input into biogas systems (i.e. large-scale biogas plants) overall corresponds to 20-40% (on average approximately 30%) of the energy content in the biogas produced. The net energy output turns negative when transport distances exceed approximately 200 km (manure), or up to 700 km (slaughterhouse waste). Large variations exist in energy efficiency among the biogas systems studied. These variations depend both on the properties of the raw materials studied and on the system design and allocation methods chosen. The net energy output from biogas systems based on raw materials that have high water content and low biogas yield (e.g. manure) is relatively low. When energy-demanding handling of the raw materials is required, the energy input increases ...

2006-03-01

279

Lightweight electric-powered vehicles. Which financial incentives after the large-scale field tests at Mendrisio?

Role-limiting approaches support knowledge acquisition (KA) by centering knowledge base construction on common types of tasks or domain-independent problem-solving strategies. Within a particular problem-solving strategy, domain-dependent knowledge plays specific roles. A KA tool then helps a user to fill these roles. Although role-limiting approaches are useful for guiding KA, they are limited because they only support users in filling knowledge roles that have been built in by the designers of the KA system. EXPECT takes a different approach to KA by representing problem-solving knowledge explicitly, and deriving from the current knowledge base the knowledge gaps that must be resolved by the user during KA. This paper contrasts role-limiting approaches and EXPECT`s approach, using the propose-and-revise strategy as an example. EXPECT not only supports users in filling knowledge roles, but also provides support in making ...

1996-12-31

280

Tax management strategies with multiple risky assets

How should lightweight electric-powered vehicles be promoted, after the large-scale fleet test being conducted at Mendrisio (southern Switzerland) is completed in 2001, and are there reasons to put question marks behind the current approach? The demand for electric vehicles, and particularly the one in the automobile category, has remained at a persistently low level. As it proved, any appreciable improvement of this situation is almost impossible, even with substantial financial incentives. However, the unsatisfactory sales figures have little to do with the nature of the fleet test itself or with the specific conditions at Mendrisio. The problem is rather of structural nature. For (battery-operated) electric cars the main problem at present is the lack of an expanding market which could become self-supporting with only a few additional incentives. Various strategies have been evaluated. Two alternatives were considered in particular: a ...

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281

British Library Electronic Table of Contents (United Kingdom)

We study the consumption-portfolio problem in a setting with capital gain taxes and multiple risky stocks to understand how short selling influences portfolio choice with a shorting-the-box restriction. Our analysis uncovers a novel trading flexibility strategy whereby, to minimize future tax-induced trading costs, the investor optimally shorts one of the stocks (or equivalently, buys put options) even when no stock has an embedded gain. Alternatively, an imperfect form of shorting the box can reduce aggregate equity exposure ex post. Given these two short selling strategies, it is common for an unconstrained investor to short some equity while a constrained investor holds a positive investment in all stocks. With no shorting, the benefit of trading separately in multiple stocks is not eco...

2006-01-01

282

Strategy and development means of the energy efficiency and renewable energies sources in France; Strategie et moyens de developpement de l'efficacite energetique et des sources d'energies renouvelables en France

Strategies to Promote High School Students’ Healthful Food Choices

In the framework of the renewable energies development policy and the energy mastership wanted by the Government, a document has been asked by the Prime Minister. It evaluates the development prospects at long and medium dated, of the main chains of renewable energies production taking into account the national developable deposits size, the technologies assessment, the environmental impacts and the competition facing the traditional energies. It evaluates the measures leading to an increasing efficiency. Measures concerning the regulations, the budget, and the fiscality are also discussed. From these analysis, a national strategy for actions in favor the renewable energies, are proposed. (A.L.B.)

2000-09-01

283

British Library Electronic Table of Contents (United Kingdom)

Studies have suggested that skill-building through hands-on cooking as a nutrition education strategy, is effective to improve overall dietary quality among participants. FamilyCook Productions' ''Diet for a Healthy Planet with Teen Battle Chefs(TM)'' curriculum using this approach, was piloted in 2008 in a Brooklyn public high school resulting in a statistically significant improvements in dietary quality as well as attitudinal improvements and efforts by students to support changes in school food service. Program evaluation used the RE-AIM framework and employed both quantitative and qualitative strategies including pre and post program surveys, focus groups, and weekly electronic teacher feedback. The program has since grown to over 85 high schools in 16 states.

2011-01-01

284

Optimal invasive species management under multiple uncertainties

British Library Electronic Table of Contents (United Kingdom)

The management programs for invasive species have been proposed and implemented in many regions of the world. However, practitioners and scientists have not reached a consensus on how to control them yet. One reason is the presence of various uncertainties associated with the management. To give some guidance on this issue, we characterize the optimal strategy by developing a dynamic model of invasive species management under uncertainties. In particular, focusing on (i) growth uncertainty and (ii) measurement uncertainty, we identify how these uncertainties affect optimal strategies and value functions. Our results suggest that a rise in growth uncertainty causes the optimal strategy to involve more restrained removals and the corresponding value function to shift up. Furthermore, we also...

2011-01-01

285

Measuring interesting rules in Characteristic rule

Malaspina University-College's green building strategy

Finding interesting rule in the sixth strategy step about threshold control on generalized relations in attribute oriented induction, there is possibility to select candidate attribute for further generalization and merging of identical tuples until the number of tuples is no greater than the threshold value, as implemented in basic attribute oriented induction algorithm. At this strategy step there is possibility the number of tuples in final generalization result still greater than threshold value. In order to get the final generalization result which only small number of tuples and can be easy to transfer into simple logical formula, the seventh strategy step about rule transformation is evolved where there will be simplification by unioning or grouping the identical attribute. Our approach to measure interesting rule is opposite with heuristic measurement approach by Fudger and Hamilton where the more complex concept ...

2010-01-01

286

Isotope labeling strategies for NMR studies of RNA

This brochure describes the strategy employed by the administration of Malaspina University--College in Nanaimo, British Columbia, to implement energy-efficient plans and integrating systems and plans that would allow the institution to consume less energy, fewer resources and improve the health and well-being of its students and staff. An assessment study to identify the most problematic areas, and to develop a prioritizing strategy for their replacement was the first step, followed by rigorous adherence to a 10- year cyclical replacement schedule. The program includes replacement of rooftop ventilation units, installation of high-performance glazing units to replace single-glazed windows, implementation of an Energy Management System to monitor heating, ventilating and air conditioning systems, and a Power Smart New Building Design and Building Improvements Program. The combined cost avoidance associated with these projects is estimated to ...

2000-01-01

287

Evaluation of cost effectiveness for conservative and active management strategies for acoustic neuroma

The known biological functions of RNA have expanded in recent years and now include gene regulation, maintenance of sub-cellular structure, and catalysis, in addition to propagation of genetic information. As for proteins, RNA function is tightly correlated with structure. Unlike proteins, structural information for larger, biologically functional RNAs is relatively limited. NMR signal degeneracy, relaxation problems, and a paucity of long-range {sup 1}H-{sup 1}H dipolar contacts have limited the utility of traditional NMR approaches. Selective isotope labeling, including nucleotide-specific and segmental labeling strategies, may provide the best opportunities for obtaining structural information by NMR. Here we review methods that have been developed for preparing and purifying isotopically labeled RNAs, as well as NMR strategies that have been employed for signal assignment and structure determination.

2010-01-15

288

British Library Electronic Table of Contents (United Kingdom)

Clin. Otolaryngol. 2009, 34, 438-446. Objective: To determine whether economic costs associated with a conservative management strategy for unilateral acoustic neuroma offer an economic advantage over active management options. Design: Cost and sensitivity analysis on a prospective cohort. Setting: Single centre study within a tertiary referral centre in Toronto, Canada. Participants: 72 patients (32 males, 40 females) aged 36 to 78 years with unilateral acoustic neuroma were assigned initially to a conservative management strategy. Entry criteria were small tumour size (less than 15mm in the cerebellopontine angle), patient preference and/or significant co-morbidity. Interventions: MRI scanning was performed every 6 months for the first year, annually subsequently and then every 2-3 years...

2009-01-01

289

Effects of burrow condition and seed handling time on hoarding strategies of Edward's long-tailed rat (Leopoldamys edwardsi)

British Library Electronic Table of Contents (United Kingdom)

Many hoarding rodents use burrows not only for dwelling and protection from natural enemies, but also for food storage. However, little is known how burrows used by scatter-hoarding animals influence their foraging behaviors. In addition, handling time for a given food item has a fundamental impact on hoarding strategies of these hoarding animals: food items with longer handling time are more likely to be hoarded due to increasing predation risk because the animals spend more time outside their burrows if they consumed such food. By providing with two types of artificial burrows (aboveground vs. underground) and two types of food items (i.e. seeds) with contrasting handling times, we investigated how burrow condition and handling time co-influence hoarding strategies of a key scatter-hoard...

2010-01-01

290

Age and gender differences in various topographical orientation strategies

British Library Electronic Table of Contents (United Kingdom)

Orientation in the environment can draw on a variety of cognitive strategies. We asked 634 healthy volunteers to perform a comprehensive battery administered through an internet website (www.gettinglost.ca), testing different orientation strategies in virtual environments to determine the effect of age and gender upon these skills. Older participants (46-67years of age) performed worse than younger participants (18-30 or 31-45years of age) in all orientation skills assessed, including landmark recognition, integration of body-centered information, forming association between landmarks and body turns, and the formation and use of a cognitive map. Among all tests, however, the ability to form cognitive maps resulted to be the significant factor best at predicting the individuals' age group. ...

2011-01-01

291

Advanced experimental design applied to damage tolerance of composite materials

Why Copy Others? Insights from the Social Learning Strategies Tournament

This paper focuses on a factorial-based design strategy. The approach provides an efficient and statistically reliable means for assessing the influence of multivariable effects. It is applied to the detection and evaluation of damage in impacted composite sandwich panels. The experimental results obtained from this test strategy are utilized to form an empirical response function. The resulting polynomial relates damage area to residual compression strength at values of independent variables for which testing did not occur. The response function also identifies nonlinear interaction effects of key variabes that cannot be easily ascertained by traditional single-variable test strategies. Independent variables evaluated include core thickness, number of face sheet plys and impact energy. The methodology presented allows the designer to predict with more confidence the damage tolerance of a composite material component, and ...

1991-01-01

292

Wavelet-based Gaussian-mixture hidden Markov model for the detection of multistage seizure dynamics: A proof-of-concept study

Social learning (learning through observation or interaction with other individuals) is widespread in nature and is central to the remarkable success of humanity, yet it remains unclear why...Full Text Available

2010-04-09

293

Utilization of a Marketing Strategy at Naval Regional Medical Center Great Lakes, Great Lakes, Illinois.

BackgroundEpilepsy is a common neurological disorder characterized by recurrent electrophysiological activities, known as seizures. Without the appropriate detection strategies,...Full Text Available

294

Use of a fuzzy decision-making method in evaluating severe accident management strategies

The study examines the question of whether or not civilian marketing practices and principles can be applied in the military care setting. Using the NRMC Great Lakes as a basis, the answer is yes--consumers of military medical care are ready to be the rec...

1983-01-01

295

Usage Patterns of a Personal Health Record by Elderly and Disabled Users

In developing severe accident management strategies, an engineering decision would be made based on the available data and information that are vague, imprecise and uncertain by nature. These sorts of vagueness and uncertainty are due to lack of knowledge for the severe accident sequences of interest. The fuzzy set theory offers a possibility of handling these sorts of data and information. In this paper, the possibility to apply the decision-making method based on fuzzy set theory to the evaluation of the accident management strategies at a nuclear power plant is scrutinized. The fuzzy decision-making method uses linguistic variables and fuzzy numbers to represent the decision-maker's subjective assessments for the decision alternatives according to the decision criteria. The fuzzy mean operator is used to aggregate the decision-maker's subjective assessments, while the total integral value method is used to rank the decision ...

2002-09-01

296

Universal Cervical Length Screening and Treatment with Vaginal Progesterone to Prevent Preterm Birth: A Decision and Economic Analysis

Personal Health Records (PHRs) are increasingly recognized as a strategy to improve patient-provider communication, availability of health information, and quality of care, by making the delivery of...Full Text Available

2007-01-01

297

US EPA, Consumer Labeling Initiative Phase II Report

ObjectiveTo estimate which strategy is the most cost-effective for prevention of preterm birth and associated morbidity.Study DesignFull Text Available

2010-06-01

298

Two Proline-Rich Nuclear Localization Signals in the Amino- and Carboxyl-Terminal Regions of the Borna Disease Virus Phosphoprotein

... NE Mall Room B-607, EPA Headquarters, 401 M ... formally adopted and initiated a joint strategy for ... CLI kick-off Partner and Task Force meeting. ...

2008-10-07

299

Transplantation-Mediated Strategies to Promote Axonal Regeneration following Spinal Cord Injury

Borna disease virus (BDV) uses a unique strategy of replication and transcription which takes place in the nucleus, unlike other known, nonsegmented, negative-stranded RNA viruses of animal origin....Full Text Available

1998-12-01

300

The influence of tethered epidermal growth factor on connective tissue progenitor colony formation

Devastating central nervous system injuries and diseases continue to occur in spite of the tremendous efforts of various prevention programs. The enormity of and annual escalation of healthcare...Full Text Available

2009-11-30

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301

The great efficacy of personal and equipment assistance in reducing disability.

Strategies to combine aspirated marrow cells with scaffolds to treat connective tissue defects are gaining increasing clinical attention and use. In situations such as large defects where initial...Full Text Available

2009-09-01

302

The Waste Management Plan integration into Decommissioning Plan of the WWR-S research reactor from Romania

OBJECTIVES: Personal and equipment assistance are common strategies to reduce disability. This study sought to determine how often assistance reduces or even completely resolves health-related difficulties...Full Text Available

1997-03-01

303

The Use of Quality Benchmarking in Assessing Web Resources for the Dermatology Virtual Branch Library of the National electronic Library for Health (NeLH)

The paper presents the progress of the Radioactive Waste Management Plan which accompanies the Decommissioning Plan for research reactor WWR-S located in Magurele, Ilfov, near Bucharest, Romania. The new variant of the Decommissioning Plan was elaborated taking into account the IAEA recommendation concerning radioactive waste management. A new feasibility study for WWR-S decommissioning was also developed. The preferred safe management strategy for radioactive wastes produced by reactor decommissioning is outlined. The strategy must account for reactor decommissioning, as well as rehabilitation of the existing Radioactive Waste Treatment Plant and the upgrade of the Radioactive Waste Disposal Facility at Baita-Bihor. Furthermore, the final rehabilitation of the laboratories and reusing of cleaned reactor building is envisaged. An inventory of each type of radioactive waste is presented. The proposed waste management ...

2008-05-28

304

Technology Strategy Board | Delivering innovation | International programmes | ARTEMIS

BackgroundIn 1998, the U.K. National Health Service Information for Health Strategy proposed the implementation of a National electronic Library for Health...Full Text Available

305

Targeted plasmid integration into the human genome by an engineered zinc-finger recombinase

...challenges faced by the industrial sector by implementing a Research Agenda for Embedded Computing Systems. The Artemis JU will manage and co-ordinate open ...5 billion research programme on Embedded Computing Systems. The programme is open to organisations within the EU Member States as well as Associated ...

306

Synapse-Associated Protein 102/dlgh3 Couples the NMDA Receptor to Specific Plasticity Pathways and Learning Strategies

The development of new methods for gene addition to mammalian genomes is necessary to overcome the limitations of conventional genetic engineering strategies. Although a variety of DNA-modifying enzymes...Full Text Available

2011-09-01

307

Structural, chemical and biological aspects of antioxidants for strategies against metal and metalloid exposure

Understanding the mechanisms whereby information encoded within patterns of action potentials is deciphered by neurons is central to cognitive psychology. The multiprotein complexes formed by...Full Text Available

2007-03-07

308

Strategies for the uses of lanthanide NMR shift probes in the determination of protein structure in solutio. Application to the EF calcium binding site of carp parvalbumin.

Oxidative stress contributes to the pathophysiology of exposure to heavy metals/metalloid. Beneficial renal effects of some medications, such as chelation therapy depend at least partially on the ability...Full Text Available

2009-09-01

309

Strategies for initial management of hypertension

The homologous sequences observed for many calcium binding proteins such as parvalbumin, troponin C, the myosin light chains, and calmodulin has lead to the hypothesis that these proteins have homologous...Full Text Available

1980-10-01

310

Sperm investment in male meadow voles is affected by the condition of the nearby male conspecifics

High blood pressure (BP) is a major public health problem in India and its prevalence is rapidly increasing among urban and rural populations. Reducing systolic and diastolic BP can decrease cardiovascular...Full Text Available

2010-11-01

311

Smoking cessation and lung cancer risk in an Asian population: Findings from the Singapore Chinese Health Study

Sperm competition occurs when 2 or more males copulate with a particular female during the same reproductive cycle, and their sperm compete to fertilize the female's available eggs. One strategy that...Full Text Available

2008-11-01

312

Slow-Release Inoculation Allows Sustained Biodegradation of ?-Hexachlorocyclohexane

Background:Smoking cessation is an important strategy for reducing the harmful effects of tobacco, particularly in the prevention of lung cancer; however, prospective data on the...Full Text Available

2010-09-28

313

Sensitivity of psychophysical measures to signal processor modifications in cochlear implant users

This study investigated the feasibility of a slow-release inoculation approach as a bioaugmentation strategy for the degradation of lindane (γ-hexachlorocyclohexane [γ-HCH]). Slow-release...Full Text Available

2006-01-01

314

Selecting Folded Proteins from a Library of Secondary Structural Elements

Experienced users of the Clarion cochlear implant were tested acutely with the HiResolution (HiRes) and HiRes Fidelity120 (F120) processing strategies. Three psychophysically-based tests were...Full Text Available

2010-04-01

315

Seismicity and Stress Changes Subsequent to Destress Blasting at the Galena Mine and Implications for Stress Control Strategies.

A protein evolution strategy is described by which double-stranded DNA fragments encoding defined E. coli protein secondary structural elements (α-helices, β-strands...Full Text Available

2008-01-09

316

Restructuring Primary Health Care Markets in New Zealand: from Welfare Benefits to Insurance Markets

Destress blasting is commonly used as a stress control technique at the Galena Mine, Wallace, Idaho, where the U.S. Bureau of Mines maintains a cooperative research program with the mine operators (ASARCO). A digital seismic array and an array of borehole...

1993-01-01

317

Real-time monitoring of circadian clock oscillations in primary cultures of mammalian cells using Tol2 transposon-mediated gene transfer strategy

BackgroundNew Zealand's Primary Health Care Strategy (NZPHCS) was introduced in 2002. Its features are substantial increases in government funding delivered as capitation payments,...Full Text Available

318

Real-Time Adherence Monitoring for HIV Antiretroviral Therapy

BackgroundThe circadian rhythm in mammals is orchestrated by a central pacemaker in the brain, but most peripheral tissues contain their own intrinsic circadian oscillators. The...Full Text Available

319

Reading strategies in Stargardt's disease with foveal sparing

Current adherence assessments typically detect missed doses long after they occur. Real-time, wireless monitoring strategies for antiretroviral therapy may provide novel opportunities to proactively...Full Text Available

2010-12-01

320

Raiders of the Lost Bark: Orangutan Foraging Strategies in a Degraded Landscape

BackgroundSubjects with a ring scotoma can use two retinal loci, a foveal and a peripheral, for reading. Our aim was to investigate the relative use of both retinal loci as a function...Full Text Available

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321

ROMP from ROMP: A New Approach to Graft Copolymer Synthesis

Deforestation is rapidly transforming primary forests across the tropics into human-dominated landscapes. Consequently, conservationists need to understand how different taxa respond and adapt to these...Full Text Available

322

Process optimization of the sputtering strategy of focused Bi ion beams with standard focused ion beam (FIB) devices; Prozessoptimierung der Sputterstrategie von fokussierten Bi-Ionenstrahlen mit Standard ''Focused Ion Beam - FIB'' Anlagen.

A new strategy is presented for the synthesis of graft copolymers using only the ring-opening metathesis polymerization (ROMP). From a ROMP-derived main chain, pendant maleimide functional groups...Full Text Available

2009-06-23

323

Performance and usefulness of the Hexagon rapid diagnostic test in children with asymptomatic malaria living in the Mount Cameroon region

No abstract prepared.

2009-07-01

324

Patch Clamp Studies on Root Cell Vacuoles of a Salt-Tolerant and a Salt-Sensitive Plantago Species ¹

BackgroundRapid and correct diagnosis of malaria is considered an important strategy in the control of the disease. However, it remains to be determined how well these tests can...Full Text Available

325

Parallel Arrays of Geometric Nanowells for Assembling Curtains of DNA with Controlled Lateral Dispersion

Plantago media L. and Plantago maritima L. differ in their strategy toward salt stress, a major difference being the uptake and distribution of ions. Patch clamp techniques...Full Text Available

1990-01-01

326

Paracetamol reduces influenza-induced immunopathology in a mouse model of infection without compromising virus clearance or the generation of protective immunity

The analysis of individual molecules is evolving into an important tool for biological research, and presents conceptually new ways of approaching experimental design strategies. However, more...Full Text Available

2008-10-07

327

Nursing Research and Participant Recruitment: Organizational Challenges and Strategies

BackgroundSeasonal influenza A infection affects a significant cohort of the global population annually, resulting in considerable morbidity and mortality. Therapeutic strategies...Full Text Available

2011-05-01

328

Nucleoside Drugs Induce Cellular Differentiation by Caspase-Dependent Degradation of Stem Cell Factors

Hospitals as research environments are crucial in advancing evidence-based practice and translational research. The authors discuss issues related to hospital-based nursing research such as...Full Text Available

2010-01-01

329

Normal boundary intersection method for suppliers' strategic bidding in electricity markets: An environmental/economic approach

BackgroundStem cell characteristics are an important feature of human cancer cells and play a major role in the therapy resistance of tumours. Strategies to target cancer stem cells...Full Text Available

330

Maternal effects and range expansion: a key factor in a dynamic process?

In this paper the problem of developing optimal bidding strategies for the participants of oligopolistic energy markets is studied. Special attention is given to the impacts of suppliers' emission of pollutants on their bidding strategies. The proposed methodology employs supply function equilibrium (SFE) model to represent the strategic behavior of each supplier and locational marginal pricing mechanism for the market clearing. The optimal bidding strategies are developed mathematically using a bilevel optimization problem where the upper-level subproblem maximizes individual supplier payoff and the lower-level subproblem solves the Independent System Operator's market clearing problem. In order to solve market clearing mechanism the multiobjective optimal power flow is used with supplier emission of pollutants, as an extra objective, subject to the supplier physical constraints. This paper uses normal ...

2010-06-15

331

Mass Treatment with Azithromycin for Trachoma Control: Participation Clusters in Households

Species that depend on ephemeral habitat often evolve distinct dispersal strategies in which the propensity to disperse is closely integrated with a suite of morphological, behavioural and physiological...Full Text Available

2009-04-27

332

Long-term impact of four different strategies for delivering an on-line curriculum about herbs and other dietary supplements

BackgroundMass treatment to trachoma endemic communities is a critical part of the World Health Organization SAFE strategy. However, non-participation may not be at random, affecting...Full Text Available

333

Larvicidal effects of a neem (Azadirachta indica) oil formulation on the malaria vector Anopheles gambiae

BackgroundPrevious research has shown that internet education can lead to short-term improvements in clinicians' knowledge, confidence and communication practices. We wished to better...Full Text Available

334

Impact of Plasmodium falciparum infection on the frequency of moderate to severe anaemia in children below 10 years of age in Gabon

BackgroundLarviciding is a key strategy used in many vector control programmes around the world. Costs could be reduced if larvicides could be manufactured locally. The potential...Full Text Available

335

Idiopathic venous thromboembolism and thrombophilia

BackgroundImproving the understanding of childhood malarial anaemia may help in the design of appropriate management strategies.MethodsA...Full Text Available

336

Horizontal Transmissible Protection against Myxomatosis and Rabbit Hemorrhagic Disease by Using a Recombinant Myxoma Virus

During the past decade idiopathic venous thromboembolism has become a separate entity, a chronic illness which has required prolonged anticoagulation and other prevention strategies to avoid recurrences....Full Text Available

2011-02-15

337

HIV/AIDS Counseling Skills and Strategies: Can Testing and Counseling Curb the Epidemic?

We have developed a new strategy for immunization of wild rabbit populations against myxomatosis and rabbit hemorrhagic disease (RHD) that uses recombinant viruses based on a naturally attenuated field...Full Text Available

2000-02-01

338

Food as a Component of National Defense Strategy

Objectives:The human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) epidemic is in its third decade and has reached to alarming proportions worldwide....Full Text Available

2011-01-01

339

Feature-based rectal contour propagation from planning CT to cone beam CT

... As noted by Emma Rothschild: ... 24. Emma Rothschild, "Food Politics," Foreign Affairs, 54 (January 1976),285·86. 25. Forecast 90, pp. I1·31, 32. 26. ...

2011-05-15

340

Epidemiologic studies of electric and magnetic fields and cancer: strategies for extending knowledge.

The purpose of this work is to develop a novel feature-based registration strategy to automatically map the rectal contours from planning computed tomography (CT) (pCT) to cone beam CT (CBCT). The rectal...Full Text Available

2008-10-01

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341

Enhancing Process and Data Collection Efficiency of Peripherally Inserted Central Catheter Insertion for Justification of an Intravenous Access Program.

Epidemiologic research concerning electric and magnetic fields in relation to cancer has focused on the potential etiologic roles of residential exposure on childhood cancer and occupational exposure...Full Text Available

1993-12-01

342

Endoscopic T-tube placement in the management of lye-induced esophageal perforation: Case report of a safe treatment strategy

This purpose of this paper is to describe the optimizing Peripherally Inserted Central Catheter (PICC) insertion, revising data collection strategies, estimating workloads, and calculating the financial savings generated by the vascular access nurse (VAN)...

2004-01-01

343

Efficient discovery of ASCL1 regulatory sequences through transgene pooling

Esophageal perforation is associated with a significant risk of morbidity and mortality. We report herein a case of lye-induced esophageal perforation managed successfully by employing endoscopic T-tube...Full Text Available

344

Effect of dietary green tea extract and aerosolized difluoromethylornithine during lung tumor progression in A/J strain mice

Zebrafish transgenesis is a powerful and increasingly common strategy to assay vertebrate transcriptional regulatory control. Several challenges remain, however, to the broader application of...Full Text Available

2010-06-01

345

Effect of Chloroquine on the Toxicity in Mice of the Venom and Neurotoxins from the Snake Bungarus multicinctus,

Chemoprevention strategies to prevent the development of lung cancer in at-risk individuals are a key component in disease management. In addition to being highly effective, an ideal chemopreventive...Full Text Available

2008-08-01

346

Dose Optimization for Long-term rAAV-mediated RNA Interference in the Nigrostriatal Projection Neurons

Antivenoms are the currently available agents for treatment of snake venom intoxication in humans. The development of therapeutic strategies employing more generally available drugs could improve treatment of invenomation by reducing hypersensitive reacti...

1987-01-01

347

Dorsal cortex volume in male side-blotched lizards (Uta stansburiana) is associated with different space use strategies

Short-hairpin RNA (shRNA)–mediated gene knockdown is a powerful tool for targeted gene silencing and an emerging novel therapeutic strategy. Recent publications, however, reported unexpected...Full Text Available

2009-09-01

348

Discrimination of Schroeder-Phase Harmonic Complexes by Normal-Hearing and Cochlear-Implant Listeners

Spatial abilities have been associated with many ecologically-relevant behaviors such as territoriality, mate choice, navigation and acquisition of food resources. Differential demands on spatial...Full Text Available

2009-07-01

349

DOD (Department of Defense) Acquisition: Case Study of the MILSTAR (Military Strategic and Tactical Relay) Satellite Communications System.

The temporal fine structure (TFS) of sound contributes significantly to the perception of music and speech in noise. The evaluation of new strategies to improve TFS delivery in cochlear implants (CIs)...Full Text Available

2008-03-01

350

Current status of therapy for breast cancer worldwide and in Japan

The study of the Military Strategic and Tactical Relay (MILSTAR) program focuses on the role of the program manager and contracting officer in developing the acquisition strategy.

1986-01-01

351

Control of intestinal parasitic infections in Seychelles: a comprehensive and sustainable approach.

The results of clinical trials conducted in Europe and North America have been incorporated into treatment strategies for breast cancer in Japan. Despite the use of similar treatment regimens, why has...Full Text Available

2011-02-10

352

Comparison of deferral rates using a computerized versus written blood donor questionnaire: a randomized, cross-over study [ISRCTN84429599

Intestinal parasitic infections have been perceived as a public health problem in Seychelles for decades. A comprehensive strategy to reduce morbidity and, in the long term, transmission of intestinal...Full Text Available

1996-01-01

353

Coal Liquefaction Program: Fiscal year 1989, Summary program plan

BackgroundSelf-administered computer-assisted blood donor screening strategies may elicit more accurate responses and improve the screening process.MethodsRandomized...Full Text Available

354

Chlamydia trachomatis Load at Matched Anatomic Sites: Implications for Screening Strategies?

Program plans of the Office of Coal Technology in coal liquefaction are presented. Technology description, status, market applications, program strategy and program management descriptions are included. 2 figs. (CBS)

1989-01-01

355

CP Violation in Top Physics at the NLC

Urethral and endocervical swabs and self-collected vaginal swabs (SCVSs) and urine specimens are all used as samples for diagnosis of urogenital infection with Chlamydia trachomatis....Full Text Available

2007-05-01

356

CDC - NIOSH Docket: 091 - Occupational Exposure Sampling Strategies...

Top quark is extremely sensitive to non-standard CP violating phases. General strategies for exposing different types of phases at the NLC are outlined. SUSY phase(s) cause PRA in $t\\to Wb$. The transverse polarization of the $\\tau$ in the reaction $t\\to b\\tau\

1996-01-01

357

Brown elephant; Der braune Elefant

to Protect Workers' Rights); 2/28/07 [PDF - 1,030 KB] Submission to the docket from Eninger (private person); 3/1/07 [PDF - 174 KB] Submission to the docket from Farber (private...

2011-10-02

358

Blood conservation strategies to reduce the need for red blood cell transfusion in critically ill patients

The German state of Sachsen is a synonym for brown coal production. The elections to the state parliament will decide the future of this echnology and of climate protection strategies like renewable energy sources. A renewables fraction of 82 percent of renewables-derived electric power may be possible by 2020. (orig.)

2009-08-15

359

Biomechanical Issues in Endovascular Device Design

Anemia commonly affects critically ill patients. The causes are multifactorial and include acute blood loss, blood loss from diagnostic testing and blunted red blood cell production. Blood transfusions...Full Text Available

2008-01-01

360

Bacterial Particle Endocytosis by Epithelial Cells Is Selective and Enhanced by Tumor Necrosis Factor Receptor Ligands?

The biomechanical nature of the arterial system and its major disease states provides a series of challenges to treatment strategies. Endovascular device design objectives have mostly centered on short-term...Full Text Available

2009-02-01

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361

Automaticity and conduction properties of bio-artificial pacemakers assessed in an in vitro monolayer model of neonatal rat ventricular myocytes

Bacterial pathogens use virulence strategies to invade epithelial barriers, but active processes of epithelial cells may also contribute to the endocytosis of microbial particles. To focus on the latter,...Full Text Available

2009-03-01

362

Aquatic Resource Monitoring

AimsA better understanding of the ionic mechanisms for cardiac automaticity can lead to better strategies for engineering bio-artificial pacemakers. Here, we attempted to better...Full Text Available

2010-08-01

363

Approaches to enhancing the quality of drug therapy. A joint statement by the CMA and the Canadian Pharmaceutical Association. Canadian Medical Association.

...research strategy and plans Aquatic resource monitoring research programs, EMAP and STAR grants Go To EMAP homepage Go To Top Bibliography References for survey designs, statistical analyses , program documentation, and monitoring reports. Reports, abstracts and links to electronic versions Go To Top Frequently Asked Questions ...

364

Analysis of target cell susceptibility as a basis for the development of a chemoprotective strategy against benzene-induced hematotoxicities.

This joint statement was developed by the CMA and the Canadian Pharmaceutical Association, a national association of pharmacists, and includes the goal of drug therapy, strategies for collaboration...Full Text Available

1996-09-15

365

An overview of prechronic and chronic toxicity/carcinogenicity experimental study designs and criteria used by the National Toxicology Program.

A goal of our research is to identify biochemical factors that underlie the susceptibility of bone marrow cell populations to benzene metabolites so as to develop a mechanistically based chemoprotective...Full Text Available

1996-12-01

366

An integrative multi-dimensional genetic and epigenetic strategy to identify aberrant genes and pathways in cancer

Since the establishment of the National Toxicology Program (NTP), there have been gradual changes in strategies to evaluate the overall toxicity of chemicals as well as their carcinogenic potential....Full Text Available

1990-06-01

367

Acetylation of Histones and Transcription-Related Factors

BackgroundGenomics has substantially changed our approach to cancer research. Gene expression profiling, for example, has been utilized to delineate subtypes of cancer, and facilitated...Full Text Available

368

ADP-Glucose Pyrophosphorylase, a Regulatory Enzyme for Bacterial Glycogen Synthesis

The state of chromatin (the packaging of DNA in eukaryotes) has long been recognized to have major effects on levels of gene expression, and numerous chromatin-altering strategies—including...Full Text Available

2000-06-01

369

A protocol for the production of recombinant spider silk-like proteins for artificial fiber spinning

The accumulation of α-1,4-polyglucans is an important strategy to cope with transient starvation conditions in the environment. In bacteria and plants, the synthesis of glycogen and starch occurs...Full Text Available

2003-06-01

370

A functional comparison of the hyolingual complex in pygmy and dwarf sperm whales (Kogia breviceps and K. sima), and bottlenose dolphins (Tursiops truncatus)

The extreme strength and elasticity of spider silks originate from the modular nature of their repetitive proteins. To exploit such materials and mimic spider silks, comprehensive strategies...Full Text Available

2009-01-01

371

A combination of transposable elements and magnetic cell sorting provides a very efficient transgenesis system for chicken primary erythroid progenitors

The function of the hyolingual complex in three odontocete species was investigated to compare adaptations of divergent feeding strategies, suction and ram feeding. Pygmy and dwarf sperm whales, members...Full Text Available

2007-07-01

372

A Substructure Combination Strategy to Create Potent and Selective Transthyretin Kinetic Stabilizers that Prevent Amyloidogenesis and Cytotoxicity

BackgroundStable transgenesis is an undeniable key to understanding any genetic system. Retrovirus-based insertional strategies, which feature several technical challenges when they...Full Text Available

373

A Hybrid Strategy of Offline Adaptive Planning and Online Image Guidance for Prostate Cancer Radiotherapy

Transthyretin aggregation-associated proteotoxicity appears to cause several human amyloid diseases. Rate-limiting tetramer dissociation and monomer misfolding of transthyretin (TTR) occur before...Full Text Available

2010-02-03

374

SLFP: A stochastic linear fractional programming approach for sustainable waste management.

The offline adaptive radiotherapy (ART) has been used to effectively correct and compensate the prostate motion and reduce the required margin. The efficacy depends on the characteristics of...Full Text Available

2010-04-21

375

Risk management in design engineering bids

A stochastic linear fractional programming (SLFP) approach is developed for supporting sustainable municipal solid waste management under uncertainty. The SLFP method can solve ratio optimization problems associated with random information, where chance-constrained programming is integrated into a linear fractional programming framework. It has advantages in: (1) comparing objectives of two aspects, (2) reflecting system efficiency, (3) dealing with uncertainty expressed as probability distributions, and (4) providing optimal-ratio solutions under different system-reliability conditions. The method is applied to a case study of waste flow allocation within a municipal solid waste (MSW) management system. The obtained solutions are useful for identifying sustainable MSW management schemes with maximized system efficiency under various constraint-violation risks. The results indicate that SLFP can support in-depth analysis of the interrelationships among system ...

2011-09-01

376

Review of Pacific Northwest Laboratory research on aquatic effects of hydroelectric generation and assessment of research needs

Accurate engineering cost estimates are critical in developing bids for new work, and for effective resource allocation and project control. This study reports on design estimating methods found in the literature, and on the results of two empirical studies of how estimating techniques are used in professional practice and their accuracy. The study found great reliance on a classic {open_quotes}activity analysis{close_quotes} approach to estimating design resources, and significant hazards in commonly used parametric techniques. The study found that project managers expect their estimates to be accurate (with 80% confidence interval) of between -10% to +25%. The study also found that actual bids between engineering firms had a much greater range (-40% to +45%) than can be explained by accuracy. Perhaps most importantly the study found that none of the sampled design firms used probabilistic techniques to optimize their project bids or to manage financial risk in ...

1995-06-01

377

Remobilization of boron, photosynthesis, phenolic metabolism and anti-oxidant defense capacity in boron-deficient turnip (Brassica rapa L.) plants

This report is an overview of Pacific Northwest Laboratory's (PNL) research on how hydroelectric generation affects aquatic biota and environments. The major accomplishments of this research are described, and additional work needed to permit optimal use of available data is identified. The research goals are to: (1) identify impacts of hydroelectric generation, (2) provide guidance in allocating scarce water resources, and (3) develop techniques to avoid or reduce the impacts on aquatic communities or to compensate for unavoidable impacts. Through laboratory and field experiments, an understanding is being developed of the generic impacts of hydrogeneration. Because PNL is located near the Columbia River, which is extensively developed for hydroelectric generation, it is used as a natural laboratory for studying a large-scale operating system. Although the impacts studied result from a particular system of dams and operating procedures and occur within a ...

1981-05-01

378

British Library Electronic Table of Contents (United Kingdom)

Abstract Turnip (Brassica rapa L.) plants were grown at adequate (25 mmol L-1) or low (<2.5 mmol L-1) boron (B) supply in nutrient solution for 1 month. The shoot and root dry weight was inhibited by up to 77% and 45%, respectively, in response to low B supply. The results of a retranslocation experiment showed that loaded B in the mature leaves was depleted rapidly during the experimental period and that this B was retranslocated to younger leaves as judged by B depletion from mature leaves simultaneously with the appearance of B in new leaves. Up to 89% of the B content of mature leaves was lost during 4 weeks of growth under B-deficient conditions. In addition, in B-deficient plants, a greater proportion of the total plant B was allocated to young leaves compared with B-sufficient plant...

2010-01-01

379

Neutron magnetic form factor G{sub M}{sup n}(Q{sup 2}) from quasielastic inclusive scattering data on D and {sup 4}He

Neutron magnetic form factor G_M"n(Q"2) from quasielastic inclusive scattering data on D and "4He

We analyze cross sections for quasielastic inclusive scattering of electrons on nuclei and show that the observed isolated peaks for relatively low Q{sup 2} are unique for the lightest targets. Focusing, in particular, on D and {sup 4}He, we investigate in two ways to what measure the above peaks can be allocated to nucleon-elastic processes. We first compute approximate upper limits for the nucleon-inelastic background in the quasielastic region due to inclusive {delta} excitation, and find those to be small. Far more precise is a semiphenomenological approach, where the dominance of nucleon-elastic processes is translated into a set of stringent requirements. We show that those are very well fulfilled for recent D data, and to a somewhat lesser extent for older D and {sup 4}He data. With knowledge of G{sub E,M}{sup p} and information on G{sub E}{sup n}, we then extract G{sub M}{sup n} and find agreement with values obtained by alternative methods. We discuss the ...

2004-07-01

380

Negotiated settlements with a cost of service backstop: The consequences for depreciation

We analyze cross sections for quasielastic inclusive scattering of electrons on nuclei and show that the observed isolated peaks for relatively low Q"2 are unique for the lightest targets. Focusing, in particular, on D and "4He, we investigate in two ways to what measure the above peaks can be allocated to nucleon-elastic processes. We first compute approximate upper limits for the nucleon-inelastic background in the quasielastic region due to inclusive #DELTA# excitation, and find those to be small. Far more precise is a semiphenomenological approach, where the dominance of nucleon-elastic processes is translated into a set of stringent requirements. We show that those are very well fulfilled for recent D data, and to a somewhat lesser extent for older D and "4He data. With knowledge of G_E_,_M"p and information on G_E"n, we then extract G_M"n and find agreement with values obtained by alternative methods. We discuss the sensitivity of the extraction method and ...

2004-07-01

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381

Milk yield and quality in Guernsey cows fed cottonseed cake-based diets partially substituted with baobab (Adansonia digitata L.) seed cake

The movement from traditional regulatory hearings to negotiated settlements represents both a departure from cost of service regulation and a relaxation of regulatory oversight. Under negotiation parties are able to renegotiate inclusions in their cost of service while simultaneously creating a profit margin for the regulated firm where none existed under the cost of service outcome of a traditional hearing. This paper constructs a model to illustrate the existence of positive gains to pipeline and shipper from the re-allocation of expenses through time in the regulated pipeline services market in Canada. Behaviour consistent with the model is observable in anecdotal and econometric evidence gathered from the library of the National Energy Board of Canada, responsible for pipeline toll regulation in Canada. Empirical investigation by into settlement procedures in the Florida electricity market reveals similar findings; however, this analysis represents the first ...

2011-03-01

382

British Library Electronic Table of Contents (United Kingdom)

The objective of this study was to determine the effects of partially substituting cottonseed cake with graded levels of baobab (Adansonia digitata L.) seed cake (BSC) on milk yield and quality in Guernsey cows. Sixteen cows in mid-lactation and in their third parity were allocated to diets containing 0% (control), 5%, 10%, and 15% BSC in a completely randomized design. Each cow was given a daily feed ration of 6?kg and a basal diet of soya bean stover ad libitum. There were no differences in daily feed intake (P?>?0.05), but basal intake differed among all treatment groups with cows on the control diet having the highest intake (30???0.34?kg/day). Mean daily milk yield differed (P?P?P?P?P?>?0.05). These results indicate that BSC can substitute soya bean cake in dairy diets, but milk produ...

2011-01-01

383

Joint Receiver and Transmitter Optimization for Energy-Efficient CDMA Communications

Iodixanol in cerebral computed tomography: a randomized, double-blind, phase-III, parallel study with iodixanol and iohexol

This paper focuses on the cross-layer issue of joint multiuser detection and resource allocation for energy efficiency in wireless CDMA networks. In particular, assuming that a linear multiuser detector is adopted in the uplink receiver, the case considered is that in which each terminal is allowed to vary its transmit power, spreading code, and uplink receiver in order to maximize its own utility, which is defined as the ratio of data throughput to transmit power. Resorting to a game-theoretic formulation, a non-cooperative game for utility maximization is formulated, and it is proved that a unique Nash equilibrium exists, which, under certain conditions, is also Pareto-optimal. Theoretical results concerning the relationship between the problems of SINR maximization and MSE minimization are given, and, resorting to the tools of large system analysis, a new distributed power control algorithm is implemented, based on very little prior information about the user of ...

2007-01-01

384

Integration of turbo-generator modules in digital transient network analyzer

Iodixanol is a new nonionic dimer, isotonic with blood at all clinically relevant concentrations. Iodixanol (270 mg I/ml) was compared in a double-blind, randomized, parallel-group, phase-III study to the monomeric nonionic iohexol (300 mg I/ml) for evaluation of safety, tolerability and radiographic efficacy during cerebral CT. One hundred adult patients scheduled to undergo contrast-enhanced cerebral CT were randomly allocated to receive either iodixanol or iohexol. All completed the trial. Safety was evaluated by recording discomfort and other adverse events, tolerance by assessing intensity and incidence of discomfort. Radiographic efficacy was assessed from the diagnostic information and the radiographic density. No serious adverse events occurred. One patient (2 %) in the iodixanol group and one patient (2 %) in the iohexol group experienced a transient reddening at the neck and lower neck-line, respectively. Both contrast agents were well tolerated. One ...

1999-09-01

385

Increase in the number of distributed power generation installations in electricity distribution grids - Project findings; Zunahme der dezentralen Energieerzeugungsanlagen in elektrischen Verteilnetzen: Erkenntnisse aus dem Projekt

The behavior of a small power system consisting of two interconnected generators is simulated in real-time by a prototype Digital Transient Network Analyzer (TNA). The prototype Digital TNA consists of two Computational Modules and one I/O Module. The Modules communicate with each other through ribbon cables. Each Computational Module simulates one Turbo-Generator, its Transformer, its Governor, Exciter, and Power System Stabilizer Systems. The numerical integration is shared by two TMS320C30 DSPs at a step-size of 100 microseconds in real-time. The I/O module post-processes the state variables and presents selected information for analog display. The paper presents oscillograms from a test program which includes symmetry checks and behavioral checks against well known waveforms of hunting oscillations, synchronization out-of-phase torques, and subsynchronous resonance phenomena. The success of the Digital TNA depends on: (a) the theoretical method of Decoupled Partitioning so that ...

1994-05-01

386

Geometry optimization of Fresnel-collectors with economic assessment

This is the eighth part of a ten-part final report for the Swiss Federal Office of Energy (SFOE) on a project that looked into potential problems relating to the Swiss electricity distribution grid with respect to the increasing number of distributed power generation facilities being put into service. The identification of special conditions for the grid's operation and future development that take increasing decentralised power production into account are discussed. The results of the project activities encompass the analysis and evaluation of various problem areas associated with planning and management of the grid during normal operation and periods of malfunction, as well as required modifications to safety systems and grid configurations. This seventh appendix to the main report summarises and discusses the knowledge gained during the project and attempts to provide answers to various questions posed by the use of distributed power generation in medium and low-voltage ...

2003-07-01

387

Free-air CO{sub 2} enrichment (FACE) enhances biomass production in a short-rotation poplar plantation

The Fresnel solar collector is a promising concept to reduce the electricity cost price in solar thermal power plants. The optical performance of a Fresnel collector depends on material properties, on its geometric layout and on the level of optical accuracy that can be obtained. A variety of geometric parameters, e.g. the height of the absorber, the number, size and distance of primary mirrors in.uence the shading and blocking of rays and the amount of rays missing the absorber. To evaluate the in.uence of the parameter variation regarding the electricity cost price and to yield an optimization, the optical performance is assessed with an annual simulation based on hourly weather-data. To permit a consideration of changes in collector cost according to different geometric layouts, cost factors where allocated to geometric parameters. The paper presents the method and the simulation results of the optimization under different boundary conditions and shows how the ...

2004-07-01

388

Free-air CO_2 enrichment (FACE) enhances biomass production in a short-rotation poplar plantation

The possible contribution of short rotation cultures (SRC) to carbon sequestration in both current and elevated carbon dioxide concentrations was investigated using the free-air carbon dioxide enrichment (FACE) technique. Three poplar species were grown in an SRC plantation for three growing seasons. Above-ground and below-ground biomass increased by 15 to 27 per cent and by 22 to 38 per cent, respectively; light-efficiency also increased as a result. Depletion of inorganic nitrogen from the soil increased after three growing seasons at elevated carbon dioxide levels, but carbon dioxide showed no effect on stem wood density. Stem wood density also differed significantly from species to species. These results confirmed inter-specific differences in biomass production in poplar, and demonstrated that elevated carbon dioxide enhanced biomass productivity and light-use efficiency of a poplar short rotation cultivation ecosystem without changing biomass allocation. The ...

2003-08-01

389

Financing Projects That Use Clean Energy Technologies: An Overview of Barriers and Opportunities

The possible contribution of short rotation cultures (SRC) to carbon sequestration in both current and elevated carbon dioxide concentrations was investigated using the free-air carbon dioxide enrichment (FACE) technique. Three poplar species were grown in an SRC plantation for three growing seasons. Above-ground and below-ground biomass increased by 15 to 27 per cent and by 22 to 38 per cent, respectively; light-efficiency also increased as a result. Depletion of inorganic nitrogen from the soil increased after three growing seasons at elevated carbon dioxide levels, but carbon dioxide showed no effect on stem wood density. Stem wood density also differed significantly from species to species. These results confirmed inter-specific differences in biomass production in poplar, and demonstrated that elevated carbon dioxide enhanced biomass productivity and light-use efficiency of a poplar short rotation cultivation ecosystem without changing biomass allocation. The ...

2003-08-01

390

Final report of the European Passive Solar Modelling Sub-Group

Project finance is asset-based financing, meaning that the project lenders have recourse only to the underlying assets of a project. It involves both debt and equity, where the debt-to-equity ratio is typically large (e.g., 70% debt to 30% equity). Debt is used when available and when it is the least expensive form of financing, with equity still needed for credit worthiness. Most important, revenue from the project must be able to generate a return to the equity investors, and pay for interest and principal on the debt, transaction costs associated with developing and structuring the project, and operations and maintenance costs. Successful project financing must provide a structure to manage and share risks in an optimal way that benefits all participants, allocating risks to those entities that are able to mitigate each specific risk, and to share information about putting risk management in the proper hands at the proper stage of project development. ...

2005-10-01

391

Enhancing Water for Food: poverty reduction through improved management of ecosystem services for sustainable food production in sub-Saharan Africa

The task of selecting reliable computer programs to simulate the performance of passive solar buildings has been assigned by the CEC to a specialized sub-group, the Modelling Sub-Group. This group has selected a detailed program for large computers, which has been commissioned and run by each participant. It has also given a reference for the analysis of a set of simple models, i.e. for mini/micro computers, pocket calculators and manual methods. These simulation techniques have been analyzed by answering an original questionnaire, making test runs of the models with building and climatic data, and comparing the results obtained with the large program. The best manual method has been included in the Passive Solar Handbook prepared by the Passive Solar Working Group. The MSG has also established a comparative table of all the selected simplified models, in order to make the designer able to do a first selection among them, in accordance with the hardware he has at his disposal, the ...

1985-01-01

392

Effect of a reminder video using a mobile phone on the retention of CPR and AED skills in lay responders.

ObjectivesIn the long term, we aim to improve understanding of the relationships between ecosystem services, water resources, food production and poverty in Sub-Saharan Africa. Specifically, we seek to understand how local communities deal with climate-related risk and uncertainty and the opportunities they have - or could have - in shaping adaptation planning around pro-poor, small-scale irrigation and to identify priorities for ecosystem management, particularly in terms of pro-poor water allocation. In [continued...]DescriptionIncreased food production is widely considered to be a fundamental step toward the reduction of poverty in Sub-Saharan Africa (SSA). Although the agricultural sector account for two-thirds of the labour force, SSA is the only region in the world where per capita food production declined over the latter half of the 20th century. It also remains highly vulnerable to extreme climate variability and future climate change as almost all ...

2010-01-31

393

ERP effects of methylphenidate and working memory load in healthy adults during a serial visual working memory task.

BACKGROUND: : Skills related to cardiopulmonary resuscitation (CPR) and automated external defibrillator (AED) use by lay responders decay rapidly after training, and efforts are required to maintain competence among trainees. We examined whether repeated viewing of a reminder video on a mobile phone would be an effective means of maintaining CPR and AED skills in lay responders. METHODS: : In a single-blind case-control study, 75 male students received training in CPR and AED use. They were allocated either to the control or to the video-reminded group, who received a memory card containing a video clip about CPR and AED use for their mobile phone, which they were repeatedly encouraged to watch by SMS text message. CPR and AED skills were assessed in scenario format by examiners immediately and 3 months after initial training. RESULTS: : Three months after initial training, the video-reminded group showed more accurate airway opening (PCPR after defibrillation ...

2011-09-26

394

Difference Antenna Selection and Power Allocation for Wireless Cognitive Systems

The objective of the study was to investigate neuronal processing during the encoding, retention and retrieval phases of a serial visual working memory task. Particularly, we were interested in how these phases are affected by working memory load and how processing is modulated by methylphenidate. Healthy adults were asked to memorize the order of four, five or six pictures under methylphenidate (20mg) and under placebo while brain electrical activity was recorded. On the performance level, the number of correct responses decreased with increasing working memory load. Concerning brain electrical activity, in the encoding phase P3 amplitudes increased at midline electrodes with increasing memory load while load had no effect in the retention and retrieval phase. Medication neither influenced performance nor the different processing stages significantly. Our data provide evidence that during the encoding phase more attentional resources are allocated in trials with ...

2010-07-17

395

Are there alternative insurance coverage models to enhance financial security for nuclear liability?; Alternative Deckungsmodelle fuer die Nuklearhaftpflicht?

In this paper, we propose an antenna selection method in a wireless cognitive radio (CR) system, namely difference selection, whereby a single transmit antenna is selected at the secondary transmitter out of $M$ possible antennas such that the weighted difference between the channel gains of the data link and the interference link is maximized. We analyze mutual information and outage probability of the secondary transmission in a CR system with difference antenna selection, and propose a method of optimizing these performance metrics of the secondary data link subject to practical constraints on the peak secondary transmit power and the average interference power as seen by the primary receiver. The optimization is performed over two parameters: the peak secondary transmit power and the difference selection weight $\\delta\\in [0, 1]$. We show that, difference selection using the optimized parameters determined by the proposed method can be, in many cases of interest, superior to a so ...

2010-01-01

396

Application of quality improvement techniques to meet coke battery environmental regulations

The proposed ERICAM model exhibits deficiencies of a nature making it inacceptable to responsible governments. These deficiencies are: it does not provide the required financial security. The availability of insurance coverage will be dependent on the situation in the financial markets. Pricing will not be determined by the absolute probability of incidents causing damage, so that this may entail a distortion of allocations of resources. (orig./HP) [Deutsch] Das ERICAM Modell hat Konstruktionsmaengel, dass es sicher fuer verantwortliche Regierungen nicht in Frage kaeme, dessen Realisierung in Erwaegung zu ziehen. Die wichtigsten sind: Die benoetigte Sicherheit der Deckungsmittel ist nicht gegeben. Die Lage an den Finanzmaerkten dominiert die Verfuegbarkeit der Deckungsmittel. Die Preisbildung wird nicht durch die absolute Schadenswahrscheinlichkeit bestimmt, so dass eine Verfaelschung der Allokation von Ressourcen eintreten wuerde. (orig./HP)

1995-12-31

397

A Cognitive Approach to Network Monitoring in Heterogeneous Environments

Citizens Gas and Coke Utility operates three coke oven batteries, producing both foundry coke and blast furnace coke, under the trade name Indianapolis Coke. Active participation in the regulation negotiation process by the Vice President of Indianapolis Coke allowed the company to accurately anticipate the environmental regulations, long before they were set in law. Several improvements were put into motion that helps them meet the new environmental regulations. Better trained operators with new job positions dedicated solely to environmental compliance, an extensive environmental training program, and two innovations, a portable oven door milling and cleaning machine and three new computer applications are the result of team efforts. The focus of this paper is development of the computer applications designed to enhance three areas of environmental compliance. The three areas addressed by the applications are documentation and information deployment, problem solving, and resource ...

1993-01-01

398

The monogamous reproductive strategy in Lepidoptera

Introducing intelligence by means of cognition for managing, protecting, processing, and delivering of information in mobile communication systems is the way towards ubiquitous, converged and secure communications. In this context, this paper introduces the concept of quality of information (QoI). QoI means QoS while all the requirements for dependability, security, privacy and trust are satisfied at the highest possible level. This work proposes and describes an approach to network monitoring in a heterogeneous communication environment based on use of cognitive techniques and learning predictive algorithms (e.g., fuzzy logic). These methodologies are used to create an autonomy in the decision making process that is based on the calculation of key performance indicators (KPIs), which in their turn would trigger the needed radio resource management algorithms. The expected output is an improved network performance in terms of maximized throughput and faster accessibility to services, ...

2007-01-01

399

British Library Electronic Table of Contents (United Kingdom)

On the basis of literary sources and experimental data, the advantages of a monogamous reproductive strategy are analyzed. Monogamous species of Lepidoptera have no postcopulative mechanisms of control over the success of reproductive sperm competition, cryptic female choice, and, probably, the male?s nuptial gift. Selection of the sex partner and of the quality of the future generation is determined by the precopulative and copulative mechanisms of the reproductive behavior, which include chemocommunication and a ?lock-and-key? mechanism. In an experiment with one male and one female, the quota of successful mating can depend on the morphological complication of the genital apparatus of males. Cases are considered of repeated mating for some, usually monogamous, species. In comparison wit...

2011-01-01

400

Implementation and management of Daya Bay Nuclear Power Plant in-core flux thimble tube in-service inspection

Impact of different forestry strategies on the function 'carbon wells on the forest planting. Simulation and modelization at the parcel scale; Impact de differentes strategies sylvicoles sur la fonction 'puits de carbone' des peuplements forestiers. Modelisation et simulation a l'echelle de la parcelle

This article discusses the Daya Bay nuclear power plant in-core flux thimble tube in-service inspection method and strategy. High light of the multiple frequency eddy current technology adopted including frequency and probe choice, standard design, data acquisition process are involved. The wear defect-growing trends are studied on base of the history data, which contribute to the in-service inspection strategy decision. (authors)

2003-04-08

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

401

IDEAS: Journal of Public Economic Theory, Association for Public Economic Theory

In the framework of the carbon storage two forestry methods are analyzed by the author: the standing capitalization (slowing of the crops) and the spices substitution (slow growing species by fast growing species). The construction of a model taking into account the all stage of the carbon implication (biomass, soil, forest products) offers simulation and quantitative results on these methods. (A.L.B.)

2005-10-15

402

British Library Electronic Table of Contents (United Kingdom)

... Bednarek & Rowena A. Pecchenino & Sally C. Stearns [Downloadable! (restricted)] 317-327 On the Existence and Uniqueness of Pure-Strategy Nash Equilibrium in Asymmetric Rent-Seeking Contests by Takeshi Yamazaki [Downloadable! (restricted)] 2008, Volume 10, Issue 1 1-5 The Journal of Public Economic Theory at Ten Years Old by John P. Conley & Myrna Wooders [Downloadable! (restricted)] 7-26 Strategy-Proofness and the Tops-Only Property by John A. Weymark [Downloadable! (restricted)]...

403

Hope versus nursing

Hope is an essential dimension of life. Hope, according to Marcel?s thinking, is the act by which the temptation to despair is actively overcome. Hope comes alive when confronting life?s trials, darkness, illness and separation. Marcel differentiates ?I hope? from ?I hope that?. Hope as a central construct for nursing has been analysed, defined, and studied by the nursing theorist Jean Watson in her Theory of Human Caring, and Kaye Herth with her strategies (Herth Hope Index). These strategies are based on Marcel?s existential notion that human beings have an endless possibility of improving their own being.

2010-01-01

404

Global Value Chains and Open Networks: The Case of Italian Industrial Districts

British Library Electronic Table of Contents (United Kingdom)

Italian district small and medium enterprises (SMEs) developed aggressive strategies to extend their sales networks and supply chains abroad. Literature on districts offered alternative explanations about the impacts of internationalization on local manufacturing systems. The authors consider the evolution of Italian districts in the framework of global value chain approach, focusing on the role of leading firms. Based on a survey of 650 Italian SMEs and financial indicators, the paper describes the rise of a new district firm model, the open network, which becomes a key node of global value chains. The paper also analyses the relationships among internationalization, innovation strategies and performance of SMEs.

2010-01-01

405

Downstream natural gas in Europe-High hopes dashed for upstream oil and gas companies

Defense remote-handled transuranic waste implementation plan: Transuranic Waste Program System Integration Office

Access for independents to retail gas markets was a central concern in European policy reform efforts in the 1990s. Upstream oil and gas companies reacted with strategic intentions of forward integration. By late 2004, forward integration was still weak, however. An important explanation of the gap between announced strategic re-orientation and actual strategy implementation lies in the political failure of EU member states to dismantle market barriers to entry for independents. Variations between companies in downstream strategy implementation are explained by variations in business opportunities and internal company factors.

2007-01-01

406

Cogeneration and beyond: The need and opportunity for high efficiency, renewable community energy systems

This document presents a detailed schedule for the implementation of the strategy for managing defense remote-handled (RH) transuranic (TRU) waste. The baseline management strategy was defined in the Defense Remote-Handled Transuranic Waste Cost/Schedule Optimization Study and is summarized in this document. Also included are revised RH TRU waste inventory projections, current site management plans, a list of key decision points and milestones, and a discussion of uncertainties associated with management of RH TRU waste. The plans are summarized in a detailed schedule diagram and in an RH TRU waste work off diagram. 9 refs., 5 figs., 4 tabs.

1988-01-01

407

An off-shell I.R. regularization strategy in the analysis of collinear divergences

The justification, strategies, and technology options for implementing advanced district heating and cooling systems in the United States are presented. The need for such systems is discussed in terms of global warming, ozone depletion, and the need for a sustainable energy policy. Strategies for implementation are presented in the context of the Public Utilities Regulatory Policies Act and proposed new institutional arrangements. Technology opportunities are highlighted in the areas of advanced block-scale cogeneration, CFC-free chiller technologies, and renewable sources of heating and cooling that are particularly applicable to district systems.

2007-10-15

408

An investigation of passive ventilation cooling and control strategies for an educational building

We present a method for the analysis of singularities of Feynman amplitudes based on the Speer sector decomposition of the Schwinger parametric integrals combined with the Mellin-Barnes transform. The sector decomposition method is described in some details. We suggest the idea of applying the method to the analysis of collinear singularities in inclusive QCD cross sections in the mass-less limit regularizing the forward amplitudes by an off-shell choice of the initial particle momenta. It is shown how the suggested strategy works in the well known case of the one loop corrections to Deep Inelastic Scattering.

2011-01-01

409

Data Center Energy Benchmarking: Part 3 - Case Study on an ITEquipment-testing Center (No. 20)

Many non-domestic buildings, built recently in the UK, use natural means to provide ventilation for indoor air quality and thermal comfort. This paper presents monitoring results obtained from such a purpose built naturally ventilated educational building. Its performance during the summer is discussed based on monitored results. Using thermal and ventilation modelling, the paper also discusses the optimisation of the building's summer performance. Recommendations on the selection of appropriate ventilation strategies in relation to the prevailing external conditions are derived and the appropriateness of the control methods is discussed. (author)

2001-02-01

410

Rhipicephalus sanguineus: vector of a new spotted fever group rickettsia in the United States.

The data center in this study had a total floor area of 3,024 square feet (ft{sup 2}) with one-foot raised-floors. It was a rack lab with 147 racks, and was located in a 96,000 ft{sup 2} multi-story office building in San Jose, California. Since the data center was used only for testing equipment, it was not configured as a critical facility in terms of electrical and cooling supply. It did not have a dedicated chiller system but was served by the main building chiller plant and make-up air system. Additionally it was served by only a single electrical supply with no provision for backup power in the event of a power outage. The Data Center operated on a 24 hour per day, year-round cycle, and users had full-hour access to the data center facility. The study found that data center computer load accounted for 15% of the overall building electrical load, while the total power consumption attributable to the data center including allocated cooling load and lighting was ...

2007-07-01

411

Protective efficiency of dendrosomes as novel nano-sized adjuvants for DNA vaccination against birch pollen allergy

A rickettsia related to but distinct from the spotted fever agent, Rickettsia rickettsii, has been detected in 167 (18.9%) of 884 Rhipicephalus sanguineus taken off dogs in central and northern Mississippi. The organisms could readily be isolated in male meadow voles (Microtus pennsylvanicus), where it produced massive infections in the tissues of tunica vaginalis. It was practically nonpathogenic for male guinea pigs, although inoculation of these animals with infected tunica vaginalis of voles afforded in 30 of 38 instances solid immunity to challenge with virulent R. rickettsii. The Rhipicephalus rickettsia grew well in monolayers of chicken embryo fibroblast, Vero, mouse L, and HeLa cells. Cytopathogenic effects were minimal unless large concentrations of rickettsiae were used as inocula. It also could be established in embryonated hen eggs but only after injection of massive doses of L cell-propagated organisms. Serological tests (complement fixation, microagglutination and/or ...

1975-07-01

412

British Library Electronic Table of Contents (United Kingdom)

We evaluated the use of a novel gene porter (Den123-a nontoxic self-assembled dendritic spheroidal nanoparticle made of biodegradable monomers), aiming to enhance and improve the desired immune response in protection from allergy. Footpad DNA immunization in Balb/c mice was done three times using the Bet v 1a gene with or without Den123 with 2-week intervals followed by sensitization with rBetv1 (5mg) in alum twice in a weekly interval. Different doses of pCMV-Betv1 were used (10mg and 100mg). The protective role of different formulations was evaluated by measuring the IgG1, IgG2a and IgE antibody production, cytokine release of isolated splenocytes and b-hexosaminidase release from the RBL cells. Higher and increasing ratios of IgG2a/IgG1 were seen in mice which received plasmids in combi...

2006-01-01

413

Investigation of xenotropic murine leukemia virus-related virus (XMRV) in human and other cell lines.

GAMMA GLOBULIN METABOLISM IN RABBITS DURING THE ANAMNESTIC RESPONSE.

Xenotropic murine leukemia virus-related virus (XMRV) was discovered in human prostate tumors and later in some chronic fatigue syndrome (CFS) patients. However, subsequent studies have identified various sources of potential contamination with XMRV and other murine leukemia virus (MLV)-related sequences in test samples. Biological and nucleotide sequence analysis indicates that XMRV is distinct from known xenotropic MLVs and has a broad host range and cell tropism including human cells. Therefore, it is prudent to minimize the risk of human exposure to infection by evaluating XMRV contamination in cell lines handled in laboratory research and particularly those used in the manufacture of biological products. Nested DNA PCR assays were optimized for investigating XMRV gag and env sequences in various cell lines, which included MRC-5, Vero, HEK-293, MDCK, HeLa, and A549, that may be used in the development of some vaccines and other cell lines broadly used in ...

2011-10-11

414

Concise review: expanding roles for hematopoietic cellular therapy and the blood transfusion services.

1. Gamma globulin metabolism and distribution were studied employing rabbit gamma globulin (RGG)I(131) 24 times in 13 control rabbits. Similar studies were performed before and during the ananmestic response in 4 rabbits previously sensitized with a polyvalent pneumococcal vaccine. 2. During the ananmestic response, gamma-globulin levels increased from 1.0 to 6.0 gm/100 ml, and the gamma-globulin pool increased from 0.7 to 4.7 gm/kg. There was no change in the intravascular-extravascular partition of gamma globulin. 3. Gamma globulin degradation increased from 0.06 to 0.33 gm/kg/day during the 28 days of the immunization period while gamma globulin synthesis increased even further to average 0.47 gm/kg/day. Following the attainment of elevated gamma globulin levels the fractional rate of RGG-I(131) turnover increased from 8.0 to 12.5 per cent/day. 4. No differences were noted in the metabolism of homologous or autologous gamma globulin regardless of the allotypic ...

1964-04-01

415

Biotechnology developments in the livestock sector in developing countries.

Hematopoietic stem cells (HSCs) have remained at the forefront of stem cell research for the past 50 years, since the therapeutic potential of bone marrow transplantation was realized. Uniquely, among stem and progenitor cells, research progress has been made in parallel between the laboratory benchtop and hospital bedside during this period. Integral to this work has been the role of the transfusion medicine services in the collection, storage, and processing of HSCs. The next decade promises to bring further developments: with new fields of cellular therapies, stem cell vaccination, and stem cell drug testing opening up. This article summarizes exciting areas of research concerning the behavior and potential clinical applications of HSCs. For the purposes of clarity, we describe in turn the trafficking and transfer of HSCs; ex vivo expansion of HSC units from different sources; and finally, applications of specifically selected subsets of hematopoietic cells and ...

2011-09-01

416

An adjuvant autologous therapeutic vaccine (HSPPC-96; vitespen) versus observation alone for patients at high risk of recurrence after nephrectomy for renal cell carcinoma: a multicentre, open-label, randomised phase III trial

Global meat and milk consumption is exponentially increasing due to population growth, urbanization and changes in lifestyle in the developing world. This is an excellent opportunity for developing countries to improve the livestock sector by using technological advances. Biotechnology is one of the avenues for improved production in the "Livestock revolution". Biotechnology developments applied to livestock health, nutrition, breeding and reproduction are improving with a reasonable pace in developing countries. Simple bio-techniques such as artificial insemination have been well implemented in many parts of the developing world. However, advanced technologies including transgenic plant vaccines, marker assisted selection, solid state fermentation for the production of fibrolytic enzymes, transgenic fodders, embryo transfer and animal cloning are confined largely to research organizations. Some developing countries such as Taiwan, China and Brazil have considered ...

2010-01-01

417

British Library Electronic Table of Contents (United Kingdom)

Summary Background Treatment of localised renal cell carcinoma consists of partial or radical nephrectomy. A substantial proportion of patients are at risk for recurrence because no effective adjuvant therapy exists. We investigated the use of an autologous, tumour-derived heat-shock protein (glycoprotein 96)-peptide complex (HSPPC-96; vitespen) as adjuvant treatment in patients at high risk of recurrence after resection of locally advanced renal cell carcinoma. Methods In this open-label trial, patients were randomly assigned to receive either vitespen (n=409) or observation alone (n=409) after nephrectomy. Randomisation was done in a one to one ratio by a computer-generated pseudo-random number generator, with a block size of four, and was stratified by performance score, lymph node stat...

2008-01-01

418

Update of the management strategy for Oak Ridge National Laboratory Liquid Low-Level Waste

Strategy and management of network security at KEK

The strategy for management of the Oak Ridge National Laboratory`s (ORNL) radioactively contaminated liquid waste was reviewed in 1991. The latest information available through the end of 1990 on waste characterization, regulations, US Department of Energy (DOE) budget guidance, and research and development programs was evaluated to determine how the strategy should be revised. Few changes are needed to update the strategy to reflect new waste characterization, research, and regulatory information. However, recent budget guidance from DOE indicates that minimum funding will not be sufficient to accomplish original objectives to upgrade the liquid low-level waste (LLLW) system to comply with the Federal Facilities Agreement, provide long-term LLLW treatment capability, and minimize environmental, safety, and health risks. Options are presented that might allow the ORNL LLLW system to continue operations temporarily, but they ...

1995-04-01

419

[Treatment strategies in osteochondral lesions of the talus. Review of the literature].

Recently the troubles related to the network security have often occurred at KEK. According to their security policy, the authors have started the strategy against the daily attacks. It consists of two fundamental things; the monitoring and the access control. To monitor the network, the authors have installed the intrusion detection system and have managed it since 1998. For the second thing, the authors arranged three categories to classify all hosts (about 5000 hosts) at KEK according to their security level. To realize these three categories, the authors filter the incoming packet from outside KEK whether it has a SYN flag or not. The network monitoring and the access control produced good effects in keeping the security level high. Since 2000 the authors have started the transition of LAN from shared-media network to switched network. Now almost part of LAN was re-configured and in this new LAN 10 Mbps 100 Mbps/1Gbps Ethernet are supported. Currently the ...

2001-09-03

420

Toward an environmental and natural resources management strategy for ANE countries in the 1990s

The aim of this study was to compare the results of different treatment strategies for osteochondral defects (OCD) of the talus. Electronic databases from 1966 to June 2000 were systematically screened. Thirty-nine studies fulfilled our inclusion criteria. No randomized clinical trials could be identified. The results of nonoperative treatment were described in 14 studies, of excision alone in 4, of excision and curettage in 10, of excision, curettage and drilling in 21, of cancellous bone grafting in 2, of fixation in 3, and of osteochondral transplantation in 1. Good or excellent results were found in 45% of the cases. Comparison of different surgical procedures showed that excision, curettage and drilling resulted in the highest mean success rate (86%), followed by excision and curettage (76%) and excision alone (38%). From the results of this systematic review we conclude that nonoperative treatment and excision alone are not to be recommended for treatment of ...

2001-01-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

421

The DG environment project ''Dioxin emissions in candidate countries''. Scope, approach and first results

An initial draft of an environmental and natural resource strategy for the Asia Near/East region in the 1990's is presented. The report contains five chapters. Chapter I provides an analytic framework that links natural resources, their extent, quality, and management with economic growth in the region. Chapter II contains a more detailed description and analysis of key resource problems that are restricting economic growth and have a severe negative impact on standard of living and quality of life. The most serious of these are soil and water degradation; destruction of natural forests, wetlands, and coastal zones; inefficient energy use and industrial pollution; and lack of environmental services. Chapters III and IV describe 20 specific opportunities for working toward sustainable economic growth through protection and enhancement of the natural resource base. Opportunities for action were chosen on the basis of the urgency and importance of the ...

1990-01-01

422

Should high-level nuclear waste be disposed of at geographically dispersed sites?

The European Commission recently has adopted a new European Strategy for Environment and Health focusing on the growing concern over the adverse health effects caused by environmental pollution. Based on the results of various studies carried out in recent years polychlorinated dioxins and furans (PCDD/Fs) and PCBs are playing an important role in this strategy. In view of the enlargement of the European Union (EU) to include Candidate Countries (CCs) the Commission stressed the need to involve the Candidate Countries from an early stage on in the development of such a strategy. Thus two studies have been commissioned which are particularly directed to provide a) an overview on environmental levels and human exposure of dioxins and PCBs and b) an harmonised PCDD/F emission inventory for the target matrices air, water and land The latter study, entitled ''Dioxin Emissions in Candidate ...

2004-09-15

423

Impact of harvesting time on ultimate methane yield of switchgrass grown in eastern Canada

Consideration of the technical feasibility of Yucca Mountain in Nevada as the site for a high-level nuclear waste repository has led to an intense debate regarding the economic, social, and political impacts of the repository. Impediments to the siting process mean that the nuclear waste problem is being resolved by adhering to the status quo, in which nuclear waste is stored at scattered sites near major population centers. To assess the merits of alternative siting strategies--including both the permanent repository and the status quo- we consider the variables that would be included in a model designed to select (1) the optimal number of disposal facilities, (2) the types of facilities (e.g., permanent repository or monitored retrievable facility), and (3) the geographic location of storage sites. The objective function in the model is an all-inclusive measure of social cost. The intent of the exercise is not to demonstrate the superiority of any single disposal ...

1992-07-01

424

Groundwater surveillance plan for the Oak Ridge Reservation

European research in green energy production from crops has resulted in the development of full scale bioreactors that use energy crops as feedstock. Switchgrass has been touted as one of the most promising crops for energy production among several perennial grass species grown under moderate to hot climates. However, few studies have been conducted in colder climate conditions. This study examined the mesophilic methane yield of switchgrass grown under the cooler growing conditions that exist in northeastern North America. In 2007, switchgrass was harvested in late July, August and September and conserved as silage. The regrowth of plots harvested in late July was also harvested in late September as a two-cut strategy. A 30 L small-scale laboratory digester was used to anaerobically digest the switchgrass silage samples. Specific methane yield decreased considerably with advancing plant development, but was similar between the first harvest in late July and the ...

2010-07-01

425

Exemplification of the Game Theory application in auctions of exploratory blocks; Um exemplo de aplicacao de Teoria dos Jogos em leiloes de blocos exploratorios

US Department of Energy (DOE) Order 5400.1 requires the preparation of environmental monitoring plans and implementation of environmental monitoring programs for all DOE facilities. The order identifies two distinct components of environmental monitoring, namely effluent monitoring and environmental surveillance. In general, effluent monitoring has the objectives of characterizing contaminants and demonstrating compliance with applicable standards and permit requirements, whereas environmental surveillance has the broader objective of monitoring the effects of DOE activities on on- and off-site environmental and natural resources. The purpose of this document is to support the Environmental Monitoring Plan for the Oak Ridge Reservation (ORR) by describing the groundwater component of the environmental surveillance program for the DOE facilities on the ORR. The distinctions between groundwater effluent monitoring and groundwater surveillance have been defined in the Martin Marietta ...

1994-07-01

426

An adaptive filter to approximate the Bayesian strategy for sonographic beamforming.

This article describes a methodology to determine the best strategy in an open bid, where oil and gas fields are the targets for exploration. Based upon the previous bid rounds for a given specific area - the Campos Basin, for that matter -, the data were statistically treated to fit a probability density function, modelling the value of bids offered by the competing companies. By means of techniques and concepts pertaining to Game Theory a balance matrix was built for values of bids made by companies as a function of the company alone in assumed bid rounds. At the end of each british auction, participants of this simultaneous game, using the rationality principle, aimed at winning the tender on the oil field aimed for, through the use of better answers with respect to its rival competitor. The game goal was maximize return on investment purchase in the decisions of lease blocks purchases in the auctions, or to try minimize its opponents gains. Proceeding with the ...

2003-07-01

427

Volcanoscope: Scoping study for increasing resilience to hazards in volcanic regions

A first-principles task-based approach to the design of medical ultrasonic imaging systems for breast lesion discrimination is described. This study explores a new approximation to the ideal Bayesian observer strategy that allows for object heterogeneity. The new method, called iterative Wiener filtering, is implemented using echo data simulations and a phantom study. We studied five lesion features closely associated with visual discrimination for clinical diagnosis. A series of human observer measurements for the same image data allowed us to quantitatively compare alternative beamforming strategies through measurements of visual discrimination efficiency. Employing the Smith-Wagner model observer, we were able to breakdown efficiency estimates and identify the processing stage at which performance losses occur. The methods were implemented using a commercial scanner and a cyst phantom to explore development of spatial filters for systems ...

2010-07-19

428

Uniform and Residue-specific {sup 15}N-labeling of Proteins on a Highly Deuterated Background

ObjectivesProject VOLCANOSCOPE will evaluate strategies (1) for applying existing and new forecasting models to volcanic eruptions, and (2) for identifying methods to improve how forecasts are communicated effectively to vulnerable communities. To link forecasting and communication, the interdisciplinary study will assess how to engage all stakeholders - from monitoring scientists, through emergency agencies, to vulnerable communities - to optimize the understanding of forecasts among different end users. [continued...]DescriptionProject VOLCANOSCOPE will evaluate strategies (1) for applying existing and new forecasting models to volcanic eruptions, and (2) for identifying methods to improve how forecasts are communicated effectively to vulnerable communities. To link forecasting and communication, the interdisciplinary study will assess how to engage all stakeholders - from monitoring scientists, through emergency agencies, to vulnerable ...

2011-01-05

429

Time-dependent 3-D dterministic transport on parallel architectures using Dantsys/MPI

A general method for stable-isotope labeling of large proteins is introduced and applied for studies of the E. coli GroE chaperone proteins by solution NMR. In addition to enabling the residue-specific {sup 15}N-labeling of proteins on a highly deuterated background, it is also an efficient approach for uniform labeling. The method meets the requirements of high-level deuteration, minimal cross-labeling and high protein yield, which are crucial for NMR studies of structures with sizes above 150 kDa. The results obtained with the new protocol are compared to other strategies for protein labeling, and evaluated with regard to the influence of external factors on the resulting isotope labeling patterns. Applications with the GroE system show that these strategies are efficient tools for studies of structure, dynamics and intermolecular interactions in large supramolecular complexes, when combined with TROSY- and CRINEPT-based experimental NMR ...

2004-07-15

430

The tactical use of constraints and structure in diagnostic problem solving

In addition to the ability to solve the static transport equation, we have also incorporated time dependence into our parallel 3-D S{sub {ital N}} code DANTSYS/MPI. Using a semi-implicit scheme, DANTSYS/MPI is capable of performing time-dependent calculations for both fissioning and pure source driven problems. We have applied this to various types of problems such as nuclear well logging and prompt fission experiments. This paper describes the form of the time- dependent equations implemented, their solution strategies in DANTSYS/MPI including iteration acceleration, and the strategies used for time-step control. Results are presented for a model nuclear well logging calculation.

1996-12-31

431

British Library Electronic Table of Contents (United Kingdom)

This paper presents a prescriptive account of diagnostic problem solving, or diagnosis, in quality and process control. This paper identifies a general strategy, named branch-and-prune, whose manifestations can be found in disciplines such as medical diagnosis, troubleshooting of devices, and model-based diagnosis in artificial intelligence. The work aims to offer a clear conceptualization of this strategy, based on the notions of structures for the search space, and constraints to the cause's nature.The idea is to treat the search space of candidate explanations as a tree structure, in which general and high-level causal directions are branched into more specific and detailed explanations. Constraints eliminate all but a few branches (pruning), which are explored in more detail. We enumer...

2011-01-01

432

The effects of various cooling strategies on surface roughness and tool wear during soft materials milling

British Library Electronic Table of Contents (United Kingdom)

This work is focused on effect of various cooling strategies on surface roughness and tool wear during computer aided milling of soft workpiece materials. These milling operations were selected as dry milling, cool air cooling milling and fluid cooling milling. A cool air cooling system was designed and produced to cool end milling tools. Cool air was produced by a vortex tube. Annealed AISI 1050 was used as the workpiece material and cutting tool material was selected as HSS-Co8 DIN 844/BN. Optimal cutting parameters were selected according to workpiece hardness from reference catalog and kept for all tests. Tool wear and surface quality were measured for three different cooling types changing from ten minute machining time to thirty minute machining time. As a result, the surface roughne...

2009-01-01

433

The Terra Nova oil field development

Studies of coupled chemical and catalytic coal conversion methods

Before expanding on the development of the Terra Nova oilfield, the author discussed the overall business strategy of Petro-Canada and identified where the Terra Nova and offshore Newfoundland oil have their place within this strategy. The principal basins and oilfields offshore Newfoundland were reviewed, then the emphasis shifted to rest on the Terra Nova development project. A whole range of topics were brought up, including the Floating Production, Storage and Offloading (FPSO) facility, the modules layout, the FPSO located at Bull Arm, and the floating production systems. The physical environment of the Grand Banks was highlighted, and the next few sections were devoted to the Terra Nova FPSO, FPSO and drill centres, the Turret General Arrangement, and Spider buoy including the disconnect/reconnect. The last four sections dealt with the animation of riser movement, the wellhead protection animation, Henry Goodrich, and operations ...

2001-07-01

434

Strategy for forecasting ice breakup and jamming: Saint John River, New Brunswick

The objective of this research was to convert coal into a soluble substance under mild conditions. The strategy involved two steps, first to breakdown the macromolecular network of coal, and second to add hydrogen catalytically. We investigated different basic reagents that could, in priciple, break down coal's structure and alkylation strategies that might enhance its solubility. We examined O- and C-alkylation, the importance of the strength of the base, the character of the added alkyl groups and other reaction parameters. This work provided new information concerning the way in which hydrogen bonding, polarization interactions between aromatic structures and covalent bonding could be disrupted and solubility enhanced. The objective of our research was to explore new organochromium chemistry that might be feasible for the hydrogenation of coal under mild conditions.

1991-12-01

435

Strategies to optimize the outcome of children given T-cell depleted HLA-haploidentical hematopoietic stem cell transplantation

Development of a strategy for forecasting river ice breakup and jamming on the Saint John River in New Brunswick was described. Methods used to identify ice jam-prone areas by simple temperature-based methods to fairly complex computer models using site specific data, were summarized. Recent technological advances in developing forecasts, including the NWRI probe for remotely measuring ice jam thickness, the RIVJAM model for determining stages upstream of an ice jam, and computational procedures for estimating the thrust exerted by ice jams against bridges, were also reviewed. Criteria and recommendations for river ice breakup and ice jamming for the Saint John River were provided. (Abstract only).

1995-12-31

436

British Library Electronic Table of Contents (United Kingdom)

The most advanced frontier of allogeneic hematopoietic stem cell transplantation (allo-HSCT) is represented by the use of an HLA-partially matched relative as donor. In this type of transplantation, donor-derived natural killer (NK) cells, which are alloreactive towardtoward recipient cells, significantly contribute to the eradication of leukemia blasts. Alloreactive NK cells may also kill host dendritic cells and T lymphocytes, thus preventing graft-versus-host disease and graft rejection, respectively. Sophisticated strategies of adoptive infusion of T-cell lines/clones specific for the most life-threatening pathogens (namely cytomegalovirus, Epstein-Barr virus, Aspergillus and Adenovirus) have been envisaged, and successfully tested in a few pilot trials, to protect the recipient in the...

2011-01-01

437

Strategies and computational tools for improving randomized protein libraries.

Shale oil value enhancement research. Quarterly report, October 1, 1993--December 31, 1993

In the last decade, directed evolution has become a routine approach for engineering proteins with novel or altered properties. Concurrently, a trend away from purely 'blind' randomization strategies and towards more 'semi-rational' approaches has also become apparent. In this review, we discuss ways in which structural information and predictive computational tools are playing an increasingly important role in guiding the design of randomized libraries: web servers such as ConSurf-HSSP and SCHEMA allow the prediction of sites to target for producing functional variants, while algorithms such as GLUE, PEDEL and DRIVeR are useful for estimating library completeness and diversity. In addition, we review recent methodological developments that facilitate the construction of unbiased libraries, which are inherently more diverse than biased libraries and therefore more likely to yield improved variants. PMID:16095966

2005-10-01

438

Resolving the impasse in American energy policy: The case for a transformational R&D strategy at the U.S. Department of Energy

The first year of this effort was focussed on the following broad objectives: (1) Analyze the molecular types present in shale oil (as a function of molecular weight distribution); (2) Determine the behavior of these molecular types in liquid-liquid extraction; (3) Develop the analytical tools needed to systematize the process development; (4) Survey the markets to assure that these have high value uses for the types found in shale oil; (5) Explore selective process means for extracting/converting shale oil components into concentrates of potentially marketable components; (6) Compile overview of the venture development strategy and begin implementation of that strategy. Each of these tasks has been completed in sufficient detail that we can now focus on filling in the knowledge gaps evident from the overview.

1997-05-01

439

British Library Electronic Table of Contents (United Kingdom)

From its inception in 1977, the U.S. Department of Energy (DOE) has been responsible for maintaining the nations nuclear stockpile, leading the country in terms of basic research, setting national energy goals, and managing thousands of individual programs. Despite these gains, however, the DOE research and development (R&D) model does not appear to offer the nation an optimal strategy for assessing long-term energy challenges. American energy policy continues to face constraints related to three "Is": inconsistency, incrementalism, and inadequacy. An overly rigid management structure and loss of mission within the DOE continues to plague its programs and create inconsistencies in terms of a national energy policy. Various layers of stove-piping within and between the DOE and national labo...

2009-01-01

440

Recent strategy and progress in Korean nuclear PLIM program

Promoting Sustainable Community Change in Support of Older Adult Physical Activity: Evaluation Findings from the Southeast Seattle Senior Physical Activity Network (SESPAN)

The strategy for the Korean nuclear power plant lifetime management (PLIM) program, which has been developed over the last 3 years, is introduced, together with descriptions of recent events and related maintenance activities. This leading Korean PLIM project has been focused on such areas as a plant data survey, screening and prioritization of systems, structures and components (SSCs), aging evaluation of major components, economic analysis and regulatory issues. The current status is outlined in terms of major tasks including aging evaluation of 13 major components. The future long-term plan which eventually aims at maximizing the economic benefit for both the utility and its customers is presented. Also described is the technical development required for plant life extension. (orig.).

1996-05-08

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441

British Library Electronic Table of Contents (United Kingdom)

Researchers have identified as effective and worthy of broader dissemination a variety of intervention strategies to promote physical activity among older adults. This paper reports results of a community-organizing approach to disseminating evidence-based interventions in a sustainable way: The Southeast Seattle Senior Physical Activity Network (SESPAN). SESPAN was implemented in Southeast Seattle, a group of multicultural neighborhoods extending 8?miles southeast of downtown Seattle, with a population of 56,469 in 2000, with 12% (7,041) aged 65 and older. The SESPAN organizing strategy involved networking to: (1) make connections between two or more community organizations to create new senior physical activity programs; and (2) build coalitions of community groups and organizations to a...

2010-01-01

442

Preclinical safety evaluations supporting pediatric drug development with biopharmaceuticals: strategy, challenges, current practices

British Library Electronic Table of Contents (United Kingdom)

Abstract Evaluation of pharmaceutical agents in children is now conducted earlier in the drug development process. An important consideration for this pediatric use is how to assess and support its safety. This article is a collaborative effort of industry toxicologists to review strategies, challenges, and current practice regarding preclinical safety evaluations supporting pediatric drug development with biopharmaceuticals. Biopharmaceuticals include a diverse group of molecular, cell-based or gene therapeutics derived from biological sources or complex biotechnological processes. The principles of preclinical support of pediatric drug development for biopharmaceuticals are similar to those for small molecule pharmaceuticals and in general follow the same regulatory guidances outlined by...

2011-01-01

443

Potential new approaches for the development of brain imaging agents for single-photon applications

Potential new approaches for the development of brain imaging agents for single-photon applications

This paper describes new strategies for the brain-specific delivery of radionuclides that can be used to evaluate regional cerebral perfusion by single photon imaging techniques. A description of several examples of interesting new strategies that have recently been reported is presented. A new approach at this institution for the brain-specific delivery of radioiodinated iodophenylalkyl-substituted dihyronicotinamide systems is described which shows good brain uptake and retention in preliminary studies in rats. Following transport into the brain these agents appear to undergo facile intracerebral oxidation to the quaternized analogues which do not recross the intact blood-brain barrier and so are effectively trapped in the brain. 49 refs., 9 figs., 1 tab.

1984-10-12

444

Polygeneration energy system based on coal gasification

The goals of this paper are to describe new strategies being pursued at several institutions for the brain-specific delivery of radionuclides that can be used to evaluate regional cerebral perfusion by single photon imaging techniques. A comprehensive review of the literature is beyond the scope of these proceedings and our goal is to, therefore, present a description of several examples of interesting new strategies that have recently been reported. In addition, the authors also describe a new approach being pursued at their institution for the brain-specific delivery of radioiodinated iodophenylaklyl-substituted dihydronicotiamide systems which shows good brain uptake and retention in preliminary studies in rats. Following transport into the brain these agents appear to undergo facile intracerebral oxidation to the quaternized analogues which do not cross the intact blood-brain-barrier and are effectively trapped in the brain.

445

Overview of eutrophication indicators to assess environmental status within the European Marine Strategy Framework Directive

Environmental pollution has become a bottleneck for the sustainable economic development of China. A 'business-as-usual' energy system in Chian is not suitable for meeting sustainability needs. It is well known that China has to use coal as the main primary energy source over the long term. Under such special conditions, to plan and construct an integrated sustainable energy system with optimal benefits in resource and energy utilization and environmental emissions is urgent. By introducing international studies and new developments in sustainable energy systems, this paper puts forward the concept that a polygeneration strategy based on coal gasification is the trend for future development of China's domestic energy industry. The framework of a polygeneration system based on oxygen-blown gasification is described and its benefits are analyzed. Finally, the starting procedure, government role, and policies for implementation ...

2003-12-15

446

British Library Electronic Table of Contents (United Kingdom)

In 2009, following approval of the European Marine Strategy Framework Directive (MSFD, 2008/56/EC), the European Commission (EC) created task groups to develop guidance for eleven quality descriptors that form the basis for evaluating ecosystem function. The objective was to provide European countries with practical guidelines for implementing the MSFD, and to produce a Commission Decision that encapsulated key points of the work in a legal framework. This paper presents a review of work carried out by the eutrophication task group, and reports our main findings to the scientific community. On the basis of an operational, management-oriented definition, we discuss the main methodologies that could be used for coastal and marine eutrophication assessment. Emphasis is placed on integrated ap...

2011-01-01

447

Optimization of decontamination strategy for CANDU-PHW reactors

Multi-channel customer management: Delighting consumers, driving efficiency

Theoretical models of the decontamination process are developed and combined with an existing model of "6"0Co production in CANDU PHW reactors to predict the effects of decontamination on long term "6"0Co build-up in reactor primary heat transport systems. The effects of decontamination interval, decontamination factor, and post-decontamination corrosion release are calculated. An optimum decontamination strategy for a Pickering G.S. type reactor is developed on the basis of a cost-benefit analysis. This study indicates that the optimum decontamination interval is approximately six years. This optimum interval is relatively insensitive to variations in the costs of personnel exposure, the cost of a decontamination, the decontamination factor, and the post-decontamination corrosion model used. (author).

448

British Library Electronic Table of Contents (United Kingdom)

In today's maturing consumer markets, emphasis is shifting from straightforward sales to a more holistic approach to customer life cycle management, with a stronger emphasis on how sales are generated and service provided all along the customer journey. Effectively managing these different marketing, sales and service channels poses a significant challenge. Companies need new strategies, structures, processes and tools to deliver customer value across all channels. A multi-channel, integrative customer model that delivers customer value and significant return on investment (ROI) requires both a strong understanding of customer preferences and behaviours and a robust IT architecture that supports the overarching customer relationship management (CRM) strategy. Even those organizations that ...

2010-01-01

449

Model-based automation system for demand-based heating and ventilation; Modellgestuetztes Mess- und Automatisierungssystem zur bedarfsgerechten Heizung und Lueftung

Managing natural resources for sustainable development. Special report

Better quality of thermal comfort as well as reduced heat energy demand and accordingly CO{sub 2} emission can be achieved by better heating and ventilation strategies in private buildings. The paper deals with a novel model-based measurement and automation system. It describes the implementation of better strategies under given technical circumstances. (orig.) [German] Durch Verbesserung der Heizungs- und Lueftungsstrategien im privaten Lebensbereich kann sowohl Heizenergie eingespart und damit die CO{sub 2}-Emission verringert, als auch die Raumbehaglichkeit verbessert werden. Der Beitrag behandelt ein modellgestuetztes Mess- und Automatisierungssystem, mit dem die Realisierung der verbesserten Strategien unter gegebenen technischen Randbedingungen praktisch erst moeglich wird. (orig.)

2003-04-01

450

Increased capability of Strassy: the decision making aid for the inspection of nuclear materials; Prolongement des capacites de Strassy: systeme d`aide a la decision pour le controle des matieres nucleaires

The report presents an overview of A.I.D. efforts, which encompass a wide range of environmental issues and support environmental training, research, and institutional development. The report's opening section details A.I.D.'s efforts to enlist host-country support for environmental programs, with specific emphasis on improving natural resource management (especially in Africa), encouraging policy change, strengthening the private sector's environmental role, and preparing environmental profiles of host countries and helping them develop conservation strategies. The ensuing sections recount A.I.D. efforts in particular topics of environmental concern (biological diversity and environmental health and safety), critical ecological areas (coastal areas and forests and fragile lands), and specific country programs (reforestation in Haiti). A brief history of the evolution of the Agency's environmental strategy ...

1987-01-01

451

Immunomodulatory strategies for relapse after haploidentical hematopoietic stem cell transplantation in hematologic malignancy patients

The paper describes the latest developments in STRASSY (Strategy Assistance System), the strategy assistance system for the inspection of nuclear materials. The user can now select the fuel cycle he wishes to investigate from an initial range of 19 facilities. An inspection interface has been developed to enable the details and dates of inspections to be modified. One of the special features of the application of STRASSY in international safeguards is the taking into account of timeliness of detection; certain aspects of the time manager algorithms are presented and analysed, including the guaranteed existence of a solution. The results of a study of diversion paths in a simplified cycle consisting of our facilities are presented. Finally, the modifications necessary to enable STRASSY to be used for a posterior analysis of inspection results are discussed. (authors). 7 refs., 3 figs.

1994-12-31

452

British Library Electronic Table of Contents (United Kingdom)

Currently, human leukocyte antigen (HLA)-mismatched/haploidentical allografts have been validated as an alternative stem cell source for patients who have no immediate access to an HLA-matched related or unrelated donor. However, relapse remains a challenge after HLA-mismatched/haploidentical hematopoietic stem cell transplantation (HSCT) that is employed in the treatment of patients with hematological malignancies. In recent years, newly developed immunomodulatory strategies, which include prophylactic and therapeutic donor lymphocyte/natural killer (NK) cell infusion, donor selection based on NK alloreactivity/non-inherited maternal antigen (NIMA), immune reconstitution promotion, and application of exogenous cytokines, have made it possible to decrease the relapse rate and improve outco...

2011-01-01

453

Greater than the sum of their parts: Combination strategies for immune regeneration following allogeneic hematopoietic stem cell transplantation

British Library Electronic Table of Contents (United Kingdom)

Cytoreductive conditioning regimes designed to allow for successful allogeneic hematopoietic stem cell transplantation (allo-HSCT) paradoxically are also detrimental to recovery of the immune system in general but lymphopoiesis in particular. Post-transplant immune depletion is particularly striking within the T cell compartment which is exquisitely sensitive to negative regulation, evidenced by the profound decline in thymic function with age. As a consequence, regeneration of the immune system remains a significant unmet clinical need. Over the past decade studies have revealed several promising therapeutic strategies to address ineffective lymphopoiesis and post-transplant immune deficiency. These include the use of cytokines such as IL-7, IL-12 and IL-15; growth factors and hormones li...

2011-01-01

454

Genetic testing for hereditary cancer: Effects of alexithymia and coping strategies on variations in anxiety before and after result disclosure

British Library Electronic Table of Contents (United Kingdom)

This study assessed the impact of the results of genetic testing for hereditary cancer from a multifactorial health psychology perspective, considering that emotional expression plays a key role in psychological adjustment. Measures of dispositional and transactional coping strategies, anxiety and alexithymia were filled out by 77 participants in a longitudinal study design. Statistical analyses were performed using general linear models and partial least squares path modelling, low-constraint methods that are particularly useful in the behavioural sciences. While anxiety levels prior to the result announcement were predictive of the distress experienced by noncarriers, considerable variability was observed for mutation carriers. Some subjects who had lower anxiety levels before the test d...

2011-01-01

455

Engaging both the Eagle and the Dragon: The Philippines' Precarious and Futile Attempt in Equi balancing

British Library Electronic Table of Contents (United Kingdom)

The article examines the limits and challenges small powers face when they adjust to systemic changes. Specifically, this article discusses the Philippines' conduct of a diplomatic strategy of equi balancing between the USA and China. In this strategy, the Philippines enhances and deepens its security relations with its strategic ally, the USA and at the same time, obtains economic assistance and politico diplomatic concessions from East Asia's emergent power, China. The Philippines' diplomatic gambit, however, is restrained by its formal alliance with the USA and its chronic territorial dispute with China over the Spratly Islands. At present, several developments are undermining Manila's efforts in playing this balancing game with Washington and Beijing. These are: the Philippines' passiv...

2010-01-01

456

Effects of surfaces and leachables on the stability of biopharmaceuticals

British Library Electronic Table of Contents (United Kingdom)

Abstract Therapeutic proteins are exposed to various potential contact surfaces, particles, and leachables during manufacturing, shipping, storage, and delivery. In this review, we present published examples of interfacial- or leachable-induced aggregation or particle formation, and discuss the mitigation strategies that were successfully utilized. Adsorption to interfaces or interactions with leachables and/or particles in some cases has been reported to cause protein aggregation or particle formation. Identification of the cause(s) of particle formation involving minute amounts of protein over extended periods of time can be challenging. Various formulation strategies such as addition of a nonionic surfactant (e.g., polysorbate) have been demonstrated to effectively mitigate adsorption-i...

2011-01-01

457

EXPLAINING THE UNEXPECTED SUCCESS OF THE SMOKING BAN IN ITALY: POLITICAL STRATEGY AND TRANSITION TO PRACTICE, 2000-2005

British Library Electronic Table of Contents (United Kingdom)

The approval (2003) and enforcement (2005) of a smoking ban in Italy have been viewed by many as an unexpectedly successful example of policy change. The present paper, by applying a processualist approach, concentrates on two policy cycles between 2000 and 2005. These had opposing outcomes: an incomplete decisional stage and an authoritative decision, enforced two years later. Through the analysis of the different phases of agenda setting, alternative specification and decision making, we have compared the quality of participation of policy entrepreneurs in the two cycles, their political strategies and, in these, the relevance of issue image. The case allows us to direct the attention of scholars and practitioners to an early phase of the policy implementation process - which we have nam...

2010-01-01

458

Depth-profiling of vertical sidewall nanolayers on structured wafers by grazing incidence X-ray flourescence

British Library Electronic Table of Contents (United Kingdom)

The Physikalisch-Technische Bundesanstalt (PTB), Germany's national metrology institute, developed an alignment strategy to specify elemental depth profiling in vertical sidewall layers on structured wafers. For this purpose, PTB's irradiation chamber for 200?mm and 300?mm silicon wafers was used to combine total-reflection X-ray fluorescence (TXRF) and grazing incidence XRF (GIXRF) techniques by employing monochromatized undulator radiation of the BESSY II electron storage ring. 3-D test structures were fabricated to develop an optimal alignment strategy allowing for depth profiling in such nanolayers. The test structures consisted of silicon bars with widths/spacings either in the ?m or in the nm range. In order to be able to differentiate the sidewalls more easily from the remainder of ...

2008-01-01

459

Correlation and interpretation of three-component survey seismic anomalies, Zamora gas field, northern Sacramento Valley, California

Correlation and interpretation of three-component survey seismic anomalies, Zamora Gas field, northern Sacramento Valley, California

A three-component seismic line acquired over the Zamora gas field, northern Sacramento Valley, California, displays conventional (P-P) and converted-wave (P-SV) seismic anomalies. Well log and seismic modeling results indicate that bright-spot reflection strengths are related to variations in fluid saturation and lithology. The P-SV reflection strengths and interval velocities provide valuable information that complements more conventional strategies such as amplitude with offset and polarity analysis. This integrated strategy can improve risk evaluation and well-site selection in areas where rapid changes in reservoir quality impact resource evaluation.

1989-03-01

460

Climate change and the African baobab (Adansonia digitata L.): the need for better conservation strategies

A three-component seismic line acquired over the Zamora gas field, northern Sacramento Valley, California, displays conventional (P-P) and converted-wave (P-SV) seismic anomalies. Well log and seismic modeling results indicate that bright-spot reflection strengths are related to variations in fluid saturation and lithology. The converted-wave reflection strengths and interval velocities provide valuable information that compliments more conventional strategies such as amplitude with offset and polarity analysis. This integrated strategy can improve risk evaluation and well site selection in areas where rapid changes in reservoir quality impact resource evaluation.

1989-04-01

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461

British Library Electronic Table of Contents (United Kingdom)

Abstract The baobab tree, with more than 300 uses and commercial value in EU and United States, has been identified as one of the most important trees to be conserved and domesticated in Africa. A decline in baobab populations because of changes in climate could have a negative effect on African livelihoods. Therefore, it is important to study the potential future distribution of this species and determine strategies for conservation. We used Maxent, 480 geo-referenced records, present and future climatic and soil layers. Different general circulation models and scenarios were selected. Models were simulated for (i) All records, (ii) East Africa and (iii) West Africa species records. For each combination, the proportion of the present habitat that might remain suitable in the future was de...

2011-01-01

462

Climate change adaptation in practice: people's responses to tidal flooding in Semarang, Indonesia

British Library Electronic Table of Contents (United Kingdom)

Abstract In many places in the world the effects of common floods are increased by climate change. In the area around the Indonesian city of Semarang, the number and effects of tidal flooding are becoming more and more severe. We found that the inhabitants used different strategies against the impact of flooding. In both the existing and the predicted flood prone areas, most people appear not to intend to leave the area, even when the floods become everyday routine. People are connected to their dwellings in a way that abandoning is not a realistic scenario. This study provides relevant information about the way people in the affected areas perceive flood risks and adaptation opportunities. Governmental policy-makers and urban planners could base their strategies and actions on this inform...

2011-01-01

463

Can the new distribution businesses deliver?

Business opportunities with international financial institutions

In this paper, the question of whether the new distribution system for the electricity supply industry can deliver a better service to customers, is discussed. In particular it discusses the requirement of customers for low cost and efficiency, with particular reference to Victoria in general and Solaris in particular. Solaris comprises the amalgamation of five ex-Municipal Electricity Undertakings and one distribution part of the former State Electricity Commission. Despite not having a set of objectives, a strategy, a common culture, appropriate processes or systems, key account management skills, marketing and customer service expertise, commercial financial expertise, commercial treasury expertise and strategic skill, it has been able to develop a business plan and strategy to satisfy the shareholder (the government), improve customer communication facilities, set up human resource management mechanisms and liaison with the community. The ...

1995-12-31

464

Bidding strategy for pumped-storage plant in pool-based electricity market

The marketing strategy developed for use in international markets by the S. M. Group International of Longueuil, Quebec, a company with interest and well-developed expertise in the environmental and energy sector, was described. The strategy is designed to aid in the selection of countries or regions of interest, in determining the sector of activity to be emphasized, in selecting a local partner or local business representatives, and in making contact locally with the people responsible for the development banks in the target countries in an effort to create awareness of the company. The company also tries, wherever possible, to promote its services to local governmental agencies through the industrial cooperation program of CIDA. Since development banks have a very conservative behaviour, past performances and constant provision of high quality services are of prime importance.

1994-12-31

465

Assessment of the efficiency of short term countermeasures following a severe accident on a PWR

This paper develops optimal bidding strategies for a pumped-storage plant in a pool-based electricity market. In the competitive regime, when compared to simple hydroelectric generator, profit of the pumped-storage plant is maximized by operating it as a generator when market clearing price is high and as a pump when the price is low. Based on forecasted hourly market clearing price, a multistage looping algorithm to maximize the profit of a pumped-storage plant is developed, considering both the spinning and non-spinning reserve bids and meeting the technical operating constraints of the plant. The proposed model is adaptive for the nonlinear three-dimensional relationship between the power produced, the energy stored, and the head of the associated reservoir. Different operating cycles for a realistic pumped-storage plant are considered and simulation results are reported and compared. (author)

2010-03-15

466

An adaptive power system stabilizer based on the self-optimizing pole shifting control strategy

In case of a severe nuclear accident at a PWR plant, countermeasures will be initiated in the short term by authorities to reduce the consequences of the atmospheric radioactive releases on the neighbouring population. Various factors influence the level of protection afforded by countermeasures. For instance, a too late intervention would lead to a Jack of efficiency in terms of dose reduction if the actual evolution of the accident is not considered. Thus, implementation of countermeasures should be optimized. In general, the projected doses (those without countermeasure) are compared with those expected when a particular countermeasure or strategy is implemented. In this paper, an in-depth analysis associates the kinetics of the release with the corresponding evolution of the dosimetric efficiency of countermeasures. This is done at different times in the short term of the accident and for various distances from the plant. Results are presented for different ...

2001-07-01

467

A universal nutrient application strategy for the bioremediation of oil-polluted beaches

An adaptive power system stabilizer (APSS) employing a new self-optimizing pole shifting control strategy and its application to a power system are described in this paper. Based on an identified model of the system, the control is computed by an algorithm which shifts the closed-loop poles of the system to some optimal locations inside the unit circle in the z-domain to minimize a given performance criterion. With the self-optimization property, outside intervention in the controller design procedure is minimized, thus simplifying the tuning procedure during commissioning. Also, a new method of calculating the variable forgetting factor in real-time parameter identification is discussed. Studies show that the proposed APSS can provide good damping of the power system over a wide operating range and significantly improve the dynamic performance of the system.

1993-12-01

468

British Library Electronic Table of Contents (United Kingdom)

Biostimulation by nutrient application is a viable technology for restoring oil-contaminated beaches. Maximizing the nutrient residence time is key for achieving a rapid cost-effective cleanup. We considered the nutrient injection strategy through a perforated pipe at the high tide line and we simulated numerically beach hydraulics, which allowed us to estimate the optimal injection flow rate of nutrient solution. Our results indicate that the optimal application is one that starts following the falling high tide and lasts for half tidal cycle. The saturated wet-front of the nutrient solution on the beach surface would move seaward with the same speed of the falling tide keeping a constant distance with the tide line. The numerical results were generalized to beaches of wide ranges of hydr...

2007-01-01

469

A study on the cooling effects of greening in a high-density city: An experience from Hong Kong

British Library Electronic Table of Contents (United Kingdom)

Greening is a useful mitigation strategy for planners mainly from a visual perspective. For high-density urban living environment such as Hong Kong, urban greening helps cooling the air and providing shade; it also helps lowering building energy consumption by providing a better outdoor boundary condition. Many researchers have also suggested that greening may be employed as a strategy for combating the ill effects of urban Heat Island (UHI). Working towards a set of better greening guidelines for urban planners, the current paper first provides a comprehensive review of planning with urban greening. It then describes parametric studies that have been conducted to investigate the preferred location, amount, and types of vegetation for urban planning. The parametric studies employed the num...

2012-01-01

470

A strategy of implementation of the improved constitutive equations for the advanced subchannel code

A new strategy of counterattacking anti-satellite based on motion camouflage

To develop the advanced subchannel analysis code, the dominant factors that influence the boiling transitional process must be taken into account in the mechanistic constitutive equations based on the flow geometries and the fluid properties. The dominant factors that influence the boiling transitional processes are (1) the gas-liquid re-distribution by cross flow, (2) the liquid film dryout, (3) the two-phase flow regime transition, (4) the droplet deposition, and (5) the spacer-droplet interaction. At first, we indicated the strategy for the development of the constitutive equations for the five dominant factors based on the experimental database by the latest measurement technique and the latest computational fluid dynamics method. Then, the problems of the present constitutive equations and the improvement plan of the constitutive equations were indicated. Finally, the layered structure for the two-phase/three-field subchannel code including the new ...

2004-10-04

471

1983 Northern Australia mine rehabilitation workshop - papers presented

Motion Camouflage (MC) is illuminated as a novel strategy in counterattacking anti-satellite by way of stealth trajectory scheduling. The dynamics model of MC in space is developed and a quadratic function with three boundary constraints is employed for trajectory determination. Based on the model a scenario is set to run the simulation. The results indicate given the designed acceleration input, the predator will be moved following a prescribed route, which precisely locates the predator between two objects at each time instant. In the last approaching phase, the motion is achieved with a big bumping rate which guarantees the power of this striking. Methods for deriving minimum fuel cost in the fixed approaching duration and the minimum approaching duration in limited acceleration input are proposed and are verified in the simulation. At last, camouflage is recognized as a multi-faceted affair, in which stealth trajectory design is considered an effective ...

2010-08-01

472

Urban Atmospheric Science

Papers presented at the workshop include: the longterm viability of mined land in Queensland; the determination and achievement of rehabilitation objectives: a state government objective; monitoring native vegetation in regenerated bauxite mines at Weipa: a belt transect method; rehabilitation strategies at the Collinsville open cut coal mine; the alteration of the environment by the construction and operation of the coal export facility at Abbot Point; some aspects of the premining environment at Collinsville; the prospects for long term revegetation of acid coal mine spoil and reject materials; recovery and stability in disturbed and artificially revegetated plant communities: a theoretical viewpoint; revegetation in the arid tropics: Mount Isa Mines' experience; Nabralek and its rehabilitation; rehabilitation and management strategies for acid mine wastes; the purpose and design of water quality monitoring networks at mine sites; ...

1983-01-01

473

Universal Basic Education: An Overall Strategy of Investment Priorities for Economic Growth.

DescriptionThis new research programme activity on Urban Atmospheric Science will deliver aspects of the NERC strategy: Next Generation Science for Planet Earth. It has been developed as part of the Environment, Pollution & Human Health theme. Research in the Environment, Pollution & Human Health theme is directed at elucidating key environmental processes that form part of a causal pathway between an environmental hazard and disease outcome, and providing a predictive capability of the risk to human heal [continued...

2012-01-01

474

Transportation 2005. [Denmark]. Trafik 2005; Problemstillinger, maal og strategier

Presents a summary of research on key aspects of the indirect effects of expanding education from grade six through grade nine, followed by a comprehensive analysis of social rates of return to investment in all levels of education in Indonesia and underemployment in urban and rural areas. (three figures, nine tables, 33 references) (MLF)

1991-12-01

475

Technology Strategy Board

The Danish Ministry of Transportation has prepared a national plan of transportation, for the years until 2005. Official policy concerning land, maritime and air transport, personal and cargo transportation, investments and expenditures is outlined. Environmental impacts of energy consumption and air pollution abatement measures are considered. (EG)

1993-01-01

476

Stanford geothermal program. Final report, July 1990--June 1996

Network Security Innovation Platform InterIm strategIc assessment ...Network Security Innovation Platform InterIm strategIc assessment June 2009 InterIm strategIc assessment June 2009 Network Security Innovation Platform ...these services continue to operate in a reliable and secure way. These electronic services underpin the economic well-being

477

Soviet military strategy in space

This report discusses the following: (1) improving models of vapor-dominated geothermal fields: the effects of adsorption; (2) adsorption characteristics of rocks from vapor-dominated geothermal reservoir at the Geysers, CA; (3) optimizing reinjection strategy at Palinpinon, Philippines based on chloride data; (4) optimization of water injection into vapor-dominated geothermal reservoirs; and (5) steam-water relative permeability.

1998-03-01

478

Revegetation of inactive U-tailing sites

This book examines the Soviet military space effort from its infancy in the 1950s to the spy craft and anti-satellite systems of today. It describes in detail the Soviet equivalents of the U.S. Star Wars program and explains technical and political issues in laymen's terms. A full text of major arms control agreements completes the volume.

1987-01-01

479

Potential Hazards from Neutrino Radiation at Muon Colliders

Soil placed over any sealant/barrier system can provide a protective mantle if the soil is not lost by erosion. Vegetation is an attractive choice for controlling erosion because it can provide an economical self-renewing cover that serves to reduce erosion by both wind and water. The objective of this research and development effort is to select and test vegetation strategies, including the choice of species and methods for revegetation that are compatible with sealant/barrier systems and are suited to soils and climates at inactive uranium mill tailings sites.

1981-02-01

480

Phytoremediation of Selenium Contaminated Soil, and Water Produces Biofortified Products and New Agricultural Byproducts

High energy muon colliders, such as the TeV-scale conceptual designs now being considered, are found to produce enough high energy neutrinos to constitute a potentially serious off-site radiation hazard in the neighbourhood of the accelerator site. A general characterization of this radiation hazard is given, followed by an order-of-magnitude calculation for the off-site annual radiation dose and a discussion of accelerator design and site selection strategies to minimize the radiation hazard.

1999-01-01

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481

Nanoparticle-assisted chemiluminescence and its applications in analytical chemistry

Based upon these processes-phytoextraction, phytovolatization and phytostabilization-a plant management remediation strategy for selenium (Se) has been developed for the Westside of Central California. Multi-year field phytoremediation studies were conducted between 2002-2007 on Se-tainted field si...

482

British Library Electronic Table of Contents (United Kingdom)

This comprehensive, critical review summarizes the use of nanoparticles in enhanced and amplified chemiluminescence detection, illustrated by different reaction strategies, electrogenerated chemiluminescence sensors, immunoassay or hybridization labels and electrogenerated chemiluminescence immunoassay or hybridization sensors. We discuss the analytical applications on the basis of validity, range and sensitivity, and draw some useful conclusions about the most sensitive approach in each type of application.

2010-01-01

483

Metastasis Detection in Sentinel Lymph Nodes: Comparison of a Limited Widely Spaced (NSABP protocol B-32) and a Comprehensive Narrowly Spaced Paraffin Block Sectioning Strategy

Integrating Phytoextraction and Biofortification: Fungal Accumulation of Selenium in Plant Materials from Phytoremediation of Agricultural Drainage

The NSABP B-32 trial is examining whether patients with initially negative sentinel lymph nodes (SLNs) who have occult metastases detected on deeper levels and cytokeratin immunohistochemistry...Full Text Available

2009-11-01

484

Imaging Three Dimensional Two-Particle Correlations for Heavy-Ion Reaction Studies

The phytomanagement of Se-polluted soil and water is one strategy that may be environmentally sustainable and cost-effective for soils and waters enriched with natural-occurring Se. Several plant species, including Indian mustard (Brassica juncea), pickleweed (Salicornia bigelovii), and other salt/S...

485

GM mosquito wild release takes campaigners by surprise - SciDev.Net

The authors report an extension of the source imaging method for analyzing three-dimensional sources from three-dimensional correlations. The technique consists of expanding the correlation data and the underlying source function in spherical harmonics and inverting the resulting system of one-dimensional integral equations. With this strategy, they can image the source function quickly, even with the extremely large data sets common in three-dimensional analyses.

2005-06-27

486

GM Mosquito Wild Release Takes Campaigners by Surprise

... The male GM mosquitoes mate with normal females to produce larvae that die unless the antibiotic tetracycline is present. In tetracycline's absence an enzyme accumulates to a toxic level, killing the larvae. The developers hope the strategy could be combined with other mosquito control methods to reduce transmission in dengue-prone areas. Ricarda Steinbrecher, a geneticist and co-director of EcoNexus -a UK-based non-profit research organisation -expressed surprise ...

487

Future research on transonic unsteady aerodynamics and its aeroelastic applications

... The male GM mosquitoes mate with normal females to produce larvae that die unless the antibiotic tetracycline is present. In tetracycline's absence an enzyme accumulates to a toxic level, killing the larvae. The developers hope the strategy could be combined with other mosquito control methods to reduce transmission in dengue-prone areas. Ricarda Steinbrecher, a geneticist and co-director of EcoNexus - a UK-based non-profit research organization - ...

488

Formula Not Shown surface diffeomorphisms have symbolic extensions

The workshop focused on strategies for promoting and developing engineering level transonic flutter prediction techniques. The technology of transonic aerodynamics is currently undergoing rapid development. Significant progress is being made to solve the inherently nonlinear equations describing unsteady motions of wings in transonic flow, while the availability of reliable and efficient computational methods will greatly enhance the ability to predict the aeroelastic behavior of modern aircraft operating under transonic flow conditions.

1987-08-01

489

British Library Electronic Table of Contents (United Kingdom)

We prove that Formula Not Shown surface diffeomorphisms have symbolic extensions, i.e. topological extensions which are subshifts over a finite alphabet. Following the strategy of Downarowicz and Maass (Invent. Math. 176:617?636, 2009) we bound the local entropy of ergodic measures in terms of Lyapunov exponents. This is done by reparametrizing Bowen balls by contracting maps in a approach combining hyperbolic theory and Yomdin?s theory.

2011-01-01

490

Explosives detection: the problem and prospects

Environmental technologies industry and global markets. A supplement to environmental technologies export: Strategic framework for US leadership. Export trade information

The history of explosives vapor detection includes almost every detection strategy known to man. Initial attempts to utilize these techniques were dismal failures. However, with the development of the Electron Capture Detector (ECD), the first promising detection of explosives vapors became possible. The present commercial explosives detectors detect the higher vapor pressure materials but not the whole spectrum. This paper describes the basic properties of explosives molecules and our research to utilize these properties for increased detection sensitivity.

1984-01-01

491

Education for Development in Underdeveloped Countries.

The present report outlines the background and issues supporting the national strategy which was developed to deploy U.S. Government resources most effectively to increase environmental technologies exports and to enhance the trade competitiveness of the U.S. environmental technologies sector. The document is a supplement to the strategic framework.

1994-04-01

492

Contact with HIV prevention services highest in gay and bisexual men at greatest risk: cross-sectional survey in Scotland

Past "elitist" development efforts modeled on Western academic education have failed to meet manpower needs but resist change due to popular preference for "modern" occupations. A new development strategy providing universal basic education and improved general living standards is needed. (Part of a theme issue on Third World educational development.) (SJL)

1981-06-01

493

Conclusions from the last five years of experiments in the field of food irradiation in Hungary

BackgroundMen who have sex with men (MSM) remain the group most at risk of acquiring HIV in the UK and new HIV prevention strategies are needed. In this paper, we examine what contact...Full Text Available

494

Computer simulation and radiation hardening of power devices to protect against failures induced by heavy ions

AGROSTER Co irradiates food packaging material and some types of spices for the meat industry. The step by step strategy of AGROSTER has been very successful. In the last year, its gamma facility was used as much as possible to irradiate food items. The government of Hungary has recognized the benefit of this technology and has given financial assistance to establish a large commercial gamma irradiator in Budapest.

1988-01-01

495

Combined heuristic with fuzzy system to transmission system expansion planning

Power devices such as MOSFETSs and IGBTs, include parasitic structures that can give rise to destructive failures such as breakdown and latch-up. To determine a suitable strategy for device radiation hardening, simulation software like MEDICI-2D can be used to model the effects of technological modifications and device parameters that are difficult to measure experimentally. (authors).

496

Closed-string tachyon condensation and loop corrected on-shell effective action of open-string tachyons

A heuristic algorithm that employs fuzzy logic is proposed to the power system transmission expansion planning problem. The algorithm is based on the divide to conquer strategy, which is controlled by the fuzzy system. The algorithm provides high quality solutions with the use of fuzzy decision making, which is based on nondeterministic criteria to guide the search. The fuzzy system provides a self-adjusting mechanism that eliminates the manual adjustment of parameters to each system being solved. (author)

2011-01-15

497

Assimilation of Remote Sensing Data into Shelf Sea Hydrodynamic Models

We propose a basic strategy to obtain a consistent on-shell effective action of open-string tachyons, on the background where closed-string tachyons are already condensed. We use sigma-model approach, basically. We regard D-instanton-like objects with appropriate weight as closed-string tachyon tadpoles, and we insert them into worldsheets to analyze the effect of closed-string tachyons.

2002-01-23

498

18-months cycle reload design verifications of Daya Bay Nuclear Power Station

DescriptionRemote sensing of the sea surface from satellites in near-polar orbits has contributed greatly to our understanding of the links between physical and biological processes in marine systems. However most of this progress has been made in open oceanic waters or major upwelling areas, and many unresolved problems are encountered in coastal regions and shelf seas. In these optically complex waters, quantitative remote sensing requires a more sophisticated interpretation strategy than that implemente [continued...

499