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Sample records for Vagina

  1. Vagina

    The vagina is the female body part that connects the womb (uterus) and cervix to the outside of the ... The vagina is a muscular tube lined with mucous membranes. Its opening is between the urethra (where urine leaves ...

  2. Vagina evaluation by MR imaging

    The author evaluated MR imaging of the vagina under different hormonal stimuli (25 patients) and assessed the role of MR imaging in the evaluation of congenital abnormalities (15 patients), primary (3) and metastatic (5) neoplasms, and reconstructive surgery (3). The findings were confirmed surgically. The appearance of the mucosa and vaginal wall was influenced by hormonal status. The presence of the vagina (45 patients), absence of the vagina (4), and the presence of duplication anomaly (3) were always accurately demonstrated on MR images. Carcinoma and metastases were depicted as tumor interrupting the low intensity signal of the muscular wall of the vagina. In two of three patients who underwent reconstructive surgery, postsurgical perivaginal abscesses developed that were correctly displayed on MR images. The normal and abnormal vaginas were exquisitely shown on MR images. For complicated congenital abnormalities, complications of postreconstructive surgery, and staging of neoplasms, MR imaging should be considered a primary imaging modality

  3. Vesicouterine fistula and blind vagina

    A case of vesicouterine fistula with blind vagina following cesarean section for obstructed labor is presented. It was surgically treated by fistulectomy, cervicoplasty and maintenance of bladder and cervical potency by catheterization. Intrauterine synechiae formation was prevented by copper T insertion and oral contraceptive pills. The patient is making uneventful a symptomatic progress planning to conceive. (author)

  4. Primary carcinoma of the vagina.

    Lilic, V; Lilic, G; Filipovic, S; Visnjic, M; Zivadinovic, R

    2010-01-01

    In this paper we reviewed the risk factors for primary carcinoma of the vagina (PCV), diagnostic and therapeutic modalities, and principles leading to rational decision-making in the individualized management of vaginal carcinoma patients. The review was based on the recent literature and our own years- long experience with the disease. PCV is a rare gynecologic malignancy accounting for about 2% of all neoplasms of the female genitals. Most of the affected women are over 60 years of age, peaking between 70 and 80 years. Only 10-15% of patients are below 50 years. Histopathologically, most common are squamous cell carcinoma (80-90%) and adenocarcinoma (4-10%). The leading risk factor for vaginal intraepithelial neoplasia (VAIN) and subsequent squamous cell vaginal carcinoma is long-lasting infection with human papillomavirus (HPV) type 16. Prognosis of the disease depends on several factors, the most important of which are age, histologic type, and tumor stage. Survival depends on the disease stage. Five -year survival rates are about 95% for stage 0, 75% for stage I, 60% for stage II, 35% for stage III, 20% for stage IVa, and 0% for IVb stage. Due to its being a rare entity, there are still controversies as to the most optimal treatment. Individualized treatment approaches have been increasingly used. In most centres, standard treatment for this cancer is radiotherapy. Some reports have shown that surgery might also be an option, while in some centres radiation is supplemented by cisplatin-based chemotherapy. The supposed advantage of radiotherapy is the preservation of the anatomy and function of the vagina. We believe that there are certain psychologic benefits with the preservation of the vagina, regardless of its function. However, preservation of the vaginal function after treatment of invasive vaginal cancer is a rare phenomenon, both in the literature and from our own experience. PMID:20658716

  5. Imaging of the vagina and vulva

    In gynecological daily practices, the vulva and vagina are examined during physical examination, however there are situations where this is not possible or it is needed to determine the extension of an injury through imaging methods. The magnetic resonance imaging is an excellent cross-sectional modality for evaluation the alterations of vulva and vagina due its multiplanar evaluation and high tecidual contrast. Other cross-sectional modalities are ultrasound and enhanced computed tomography. This paper intends to give an overview of vaginal and vulvar pathology that can be identified by the radiologist. (author)

  6. Endodermal sinus tumor of vagina in infants

    Brijesh Thakur

    2013-04-01

    Full Text Available Endodermal sinus tumor (or Yolk Sac tumor of the vagina is a rare malignant germ-cell tumor which is seen exclusively in children younger than 3 years of age. We report two cases of endodermal sinus tumor of the vagina. In both cases no radiological investigation was done and serum alpha-fetoprotein was elevated. The histopathological examination of both the tumor masses revealed vaginal endodermal sinus tumor. Periodic-acid-Schiff stain with diastase showed diastase resistant hyaline globules. These findings confirmed the diagnosis of endodermal sinus tumor in both cases. Vaginal endodermal sinus tumor is both locally aggressive and capable of metastasis. The serum alpha-fetoprotein level is a useful marker for diagnosis and monitoring the recurrence of vaginal endodermal sinus tumor in infants. Early detection and therapy is important because of its aggressive nature and good response to chemotherapy.

  7. The vagina : morphological, functional and ecological aspects

    Sjöberg, Inga

    1991-01-01

    The vagina is one organ of the body which has not been studied exhaustively. Moreover, most of the studies found in the contemporary literature have been performed on women affected by a variety of genital diseases. In the present study the vaginal epithelium was examined with a histological method, morphometry, whereby cyclical changes related to hormonal variation during the menstrual cycle were demonstrated. Determination of the quantity of estrogen receptors in the vaginal epithelium on t...

  8. Primary leiomyosarcoma of vagina: case report; Leiomiossarcoma primario de vagina: relato de caso

    Vieira, Leonardo Jose [Hospital ASCONCER Associacao Feminina de Prevencao e Combate ao Cancer, Juiz de Fora, MG (Brazil). Servico de Cirurgia; Freitas, Rosyane Rena de [Juiz de Fora Univ., MG (Brazil). Faculdade de Medicina; Oliveira, Alexandre Ferreira de [Juiz de Fora Univ., MG (Brazil). Faculdade de Medicina. Disciplina de Cirurgia Gastroenterologica; Assis, Raimunda Violante Campos de [Juiz de Fora Univ., MG (Brazil). Faculdade de Medicina. Dept. de Patologia; Cugola, Elaine Aline; Costa, Sandra Marcia Carvalho Ribeiro

    2004-07-01

    Primary malignant lesions of the vagina are uncommon and represent about 1% of all gynecological malignancies. Most of these neoplasms are carcinomas. Sarcomas comprise less than 2% of all malignant vaginal tumours. In this present article, we describe a primary vaginal leiomyosarcoma in a 40-years-old woman. (author)

  9. Rare case of primary mucinous adenocarcinoma of vagina

    Bharati Dhorepatil

    2013-01-01

    Full Text Available Here we present a rare case of primary mucinous adenocarcinoma of vagina treated successfully with wide local excision and post-operative radiotherapy. There was no recurrence even after four years.

  10. Vagina vasorum dissection during D2 lymphadenectomy for gastric carcinoma

    Jian-Jun Peng; Yu-Long He; Wen-Hua Zhan; Ping Xiao; Shi-Rong Cai; Chang-Hua Zhang; Hui Wu

    2007-01-01

    AIM:To explore the relationship between metastasis and vagina vasorum in the progress of gastric carcinoma and to find some facts and references for gastric surgeons.METHODS:One hundred and seven specimens of left or right gastric arteries (55 left and 52 right) were gathered from 59 patients undergoing radical gastrectomy for gastric carcinoma. All the frozen specimens were cut into 3 μm-thick sections and stained with hematoxylin-eosin (HE) and immunohistochemical method separately. Cytokeratin (CK) and mesothelial cells (MC) were stained with immunohistochemical method. Cancer cells inside vagina vasorum were detected and* the structure of artery wall was observed under microscope.RESULTS:Metastatic cancer cells or tubercles were found inside vagina vasorum in some stage Ⅲ or Ⅳ specimens,but not in stage Ⅰ or Ⅱ specimens. Tumor cells in vagina vasorum were CK positive in 26 specimens of 14 tumors. Among them,stage in was found in 4 specimens of 2 tumors,and stage Ⅳ in 22 specimens of 12 tumors. None of these specimens was positive for MC. The positive rate of CK increased with TNM staging. Compared with the lower part,tumors in the upper and middle parts of stomach were more,likely to metastasize into vagina vasorum.CONCLUSION:Vagina vasorum dissection should be performed during D2 lymphadenectomy for TNM stage Ⅲ or Ⅳ gastric carcinoma.

  11. Primary malignant melanoma of the vagina: a case report

    Jang, Ji Young; Kim, Do Kang; Lee, Eun Hee [College of Medicine, Catholic Univ., Seoul (Korea, Republic of); Kim, Jun Sang [College of Medicine, Chungnam National Univ., Daejeon (Korea, Republic of)

    2003-09-01

    A primary malignant melanoma of the vagina is a very rare gynecological malignant tumor. Its clinical behavior is more aggressive than that of cutaneous and vulvar melanomas. We present a case of a large sized primary melanoma of the lower third of the vagina, with a cervical lesion, in a 58-year-old postmenopausal woman. The patient was treated with conventional external radiation therapy and intracavitary radiotherapy (lCR), without surgical treatment. Although the primary lesion showed a partial response, the patient died of extensive metastases, which were found 4.5 months after the initial diagnosis. We suggest that shortening the treatment period, such as hypofractionated radiation therapy and surgical removal, and various systemic therapies for preventing early distant metastasis, are appropriate treatments for a primary malignant melanoma of the vagina, with a large tumor size.

  12. CONGENITAL ABSENCE OF THE VAGINA - RESULTS OF CONSERVATIVE TREATMENT

    LAPPOHN, RE

    1995-01-01

    Objective: To assess the efficacy of a combination of Frank's mold therapy with intercourse as a treatment for congenital vaginal aplasia. Study design: From 1973-1993, thirty-three patients with congenital aplasia of vagina and uterus were seen by one gynecologist. Patients with a partner were inst

  13. Over het ontstaan van het zure milieu in de vagina

    J.C. Hage

    1978-01-01

    textabstractDe bekleding van de vagina bestaat uit p!aveiselepitheel, dat opgebouwd is uit een basale, intermediaire en superficiële laag; de laatste bevat het meeste glycogeen (Rakoff e.a. 1944, Matter 1955, Gregoire e.a. 1971 ). De fluor vaginalis bevat glycogeen door exfoliatie van de oppervlakki

  14. SPINDLE CELL SARCOMA OF VAGINA- A CASE REPORT

    Sankareswari

    2013-04-01

    Full Text Available ABSTRACT : Malignant tumors of vagina are rare accounting for 1 to 4 % of all genital malignancies. Rarest of rare is spindle cell sarcoma of vagina having a very poor prognosis. 47yrs old, regularly menstruating woman, completed f amily, presented with hard painful ulcerated swelling near the vaginal introitus and l ower vaginal wall of 4 months duration. On examination, 2x4cms sized ulcerated growth with exc avated base, covered with necrotic material, present in the left antero-lateral lower e nd of vagina, inner to hymenal ring which was tender, hard, indurated, infiltrating, fixed to bas e and did not bleed to touch. Another nodule of size 1x1cm tender, hard, fixed and necrotic was pres ent below the external urethral meatus. HPE revealed Amelanotic malignant melanoma of vagin a. Immunohistochemistry revealed Spindle cell sarcoma of vagina. Tumor board recommen ded neo-adjuvant chemotherapy and radiotherapy (CT + EBRT. Of the recommended 50Gy, s he completed 46Gy in 23days and 1 course of chemotherapy (VAC. On review after 9 mont hs, the lesion disappeared clinically and she was advised to complete the treatment. Inspite o f radio and chemotherapy secondaries to lungs and brain could not be prevented and the patien t expired 20 months after the final diagnosis

  15. Management of radionecrosis of the vulva and distal vagina

    Twelve patients were seen between January 1983 and June 1989 with the clinical diagnosis of radionecrosis of the vulva or distal vagina. Seven patients received radiation for vulvar cancer, three for distal vaginal cancer, and two for recurrent endometrial cancer. No patient healed spontaneously and the mean delay in surgical therapy was 8.5 months. The radionecrotic site was treated with local therapy, radical local excision (with or without colostomy), or exenteration. The operative defect was closed primarily in three patients and covered with local flaps or myocutaneous flaps in seven patients. The two patients with local care still have radionecrotic ulcers. One of three patients who were closed primarily continues to have an ulcer. All other patients have healed satisfactorily except one who died after two attempts to correct the problem. Radionecrosis of the vulva and distal vagina should generally be treated surgically

  16. Management of radionecrosis of the vulva and distal vagina

    Roberts, W.S.; Hoffman, M.S.; LaPolla, J.P.; Ruas, E.; Fiorica, J.V.; Cavanagh, D. (Univ. of South Florida, Tampa (USA))

    1991-05-01

    Twelve patients were seen between January 1983 and June 1989 with the clinical diagnosis of radionecrosis of the vulva or distal vagina. Seven patients received radiation for vulvar cancer, three for distal vaginal cancer, and two for recurrent endometrial cancer. No patient healed spontaneously and the mean delay in surgical therapy was 8.5 months. The radionecrotic site was treated with local therapy, radical local excision (with or without colostomy), or exenteration. The operative defect was closed primarily in three patients and covered with local flaps or myocutaneous flaps in seven patients. The two patients with local care still have radionecrotic ulcers. One of three patients who were closed primarily continues to have an ulcer. All other patients have healed satisfactorily except one who died after two attempts to correct the problem. Radionecrosis of the vulva and distal vagina should generally be treated surgically.

  17. Radiosterilisation of the vagina in therapeutic doses - does it exist

    The endogenous genital flora is a major source of infections of the female genital tract, especially in patients with cervical or endometrial cancer. Until recently the 'radiosterilisation of the vagina', respectively a prophylactic and/or therapeutic effect of irradiation (external highvoltage as well as intracavitary-radium) concerning infections was postulated in the literature. This theory was disproved in a prospective clinical and bacteriological study covering 48 patients with advanced cervical cancer undergoing primary intracavitary radium-irradiation and 38 patients with inoperable endometrical cancer, undergoing primary iridium-192-afterloading. Following intracavitary radium for cervical cancer some typical nosocomial pathogens like Streptococcus faecalis, Enterobacter, Klebsiella, Proteus and Pseudomonas were isolated significantly more frequently than before treatment. Likewise, the mean number of aerobic bacterial species increased significantly after irradiation. Also primary Ir-192 (afterloading) irradiation did not alter the frequency of isolation of the resident flora in endometrial cancer patients. Therefore, 'radiosterilisation' of the vagina as result of radiotherapy does not exist. (orig.)

  18. Nanoparticle transport from mouse vagina to adjacent lymph nodes.

    Byron Ballou

    Full Text Available To test the feasibility of localized intravaginal therapy directed to neighboring lymph nodes, the transport of quantum dots across the vaginal wall was investigated. Quantum dots instilled into the mouse vagina were transported across the vaginal mucosa into draining lymph nodes, but not into distant nodes. Most of the particles were transported to the lumbar nodes; far fewer were transported to the inguinal nodes. A low level of transport was evident at 4 hr after intravaginal instillation, and transport peaked at about 36 hr after instillation. Transport was greatly enhanced by prior vaginal instillation of Nonoxynol-9. Hundreds of micrograms of nanoparticles/kg tissue (ppb were found in the lumbar lymph nodes at 36 hr post-instillation. Our results imply that targeted transport of microbicides or immunogens from the vagina to local lymph organs is feasible. They also offer an in vivo model for assessing the toxicity of compounds intended for intravaginal use.

  19. Nanoparticle transport from mouse vagina to adjacent lymph nodes.

    Ballou, Byron; Andreko, Susan K; Osuna-Highley, Elvira; McRaven, Michael; Catalone, Tina; Bruchez, Marcel P; Hope, Thomas J; Labib, Mohamed E

    2012-01-01

    To test the feasibility of localized intravaginal therapy directed to neighboring lymph nodes, the transport of quantum dots across the vaginal wall was investigated. Quantum dots instilled into the mouse vagina were transported across the vaginal mucosa into draining lymph nodes, but not into distant nodes. Most of the particles were transported to the lumbar nodes; far fewer were transported to the inguinal nodes. A low level of transport was evident at 4 hr after intravaginal instillation, and transport peaked at about 36 hr after instillation. Transport was greatly enhanced by prior vaginal instillation of Nonoxynol-9. Hundreds of micrograms of nanoparticles/kg tissue (ppb) were found in the lumbar lymph nodes at 36 hr post-instillation. Our results imply that targeted transport of microbicides or immunogens from the vagina to local lymph organs is feasible. They also offer an in vivo model for assessing the toxicity of compounds intended for intravaginal use. PMID:23284844

  20. Malignant peripheral nerve sheath tumor of the vagina

    Malignant peripheral nerve sheath tumors (MPNSTs) usually develop in major nerve trunks, giving rise to tumors in the proximal portions of the upper and lower extremities and trunk. The MPNSTs primarily occurring in the female genital tract are quite rare. We describe a case of MPNST of the vagina and discuss its diagnosis and treatment. This patient was treated definitively with radical local excision and is well with no signs of recurrence 2 years postoperatively. (author)

  1. Nanoparticle Transport from Mouse Vagina to Adjacent Lymph Nodes

    Byron Ballou; Andreko, Susan K.; Elvira Osuna-Highley; Michael McRaven; Tina Catalone; Bruchez, Marcel P.; Hope, Thomas J.; Labib, Mohamed E.

    2012-01-01

    To test the feasibility of localized intravaginal therapy directed to neighboring lymph nodes, the transport of quantum dots across the vaginal wall was investigated. Quantum dots instilled into the mouse vagina were transported across the vaginal mucosa into draining lymph nodes, but not into distant nodes. Most of the particles were transported to the lumbar nodes; far fewer were transported to the inguinal nodes. A low level of transport was evident at 4 hr after intravaginal instillation,...

  2. KANDIDIASIS VAGINA YANG MENDAPAT TERAPI SISTEMIK DAN TOPIKAL: SEBUAH LAPORAN KASUS

    Dewa Made Rendy Sanjaya

    2014-08-01

    Full Text Available Kandidiasis vulvovaginitis ialah penyakit jamur candida yang mengenai mukosa vagina danvulva.Penyebabnya yang tersering biasanya adalah candida albicans.Gejala klinis KandidiasisVulvovaginitis ialah gatal didaerah vulva, dan pada yang berat terdapat rasa panas,dispaneuria.lesi eritema, hiperemis dilabia mayora, dan vagina 1/3 bawah. Dilaporkan satu  kasusseorang wanita. berumur 26 tahun dengan keluhan keputihan pada daerah vagina sertamengalami kegatalan dan rasa nyeri terjadi sejak 2 minggu yang lalu. Pada gambaran klinis tampak dinding vagina eritema, erosi dengan secret putih kental. Pada pengecatan gram darisecret mukosa vagina didapatkan leukosit blastopsora dan pseudohifa. Pemerikaan KOH 10%dari sekret vagina didapatkan blastopore dan pesudohifa.Penanganan yang diberikan adalah obatsistemik dengan flukonazol 1x150 mg dosis tunggal dan topical diberikan ketokenazol cream.Prognosis kasus tersebut adalah baik..

  3. Pelvic Myxoid Leiomyoma Mass between Vagina and Rectum.

    AlShalabi, Omar; Alahmar, Fadi Obaied; Aljasem, Hazem; Alsaid, Bayan; AlShalabi, Abdulghani

    2016-01-01

    Leiomyomas are the most common pelvic tumors in women. About 20-30% of women older than 35 are affected. Rare conditions of leiomyomas have extrauterine locations. Myxoid degeneration is a rare type of leiomyoma degeneration. We report a case of solid-cystic myxoid leiomyoma in a 53-year-old woman complained of constipation, urinary hesitation, and malodorous vaginal discharge with palpable 17 × 12 cm mass between vagina and rectum. Regarding the inferior location of the mass, a perineal approach was used to enucleate it. This rare location has not been mentioned before. The woman was finally diagnosed by pathologists which was myxoid leiomyoma. PMID:27429825

  4. Management of radiation injuries of vulva and vagina

    Fraunholz, I.B.; Schopohl, B.; Boettcher, H.D. [Klinik fuer Strahlentherapie und Onkologie, Johann-Wolfgang-Goethe-Universitaet Frankfurt am Main (Germany)

    1998-11-01

    Background: Acute and late injuries of vulva and vagina are frequent and potentially serious complications in radiotherapy of gynecologic tumors. They still are reported poorly in literature. Methods: Based on a literature search a survey will be given of the modalities, which are used or recommended for prophylaxis or treatment of these radiation injuries. The principles of the different measures will be discussed with available study results. Results: Hygiene measures and the topical application of antimicrobial or granulation stimulating substances, which is mostly based on long standing clinical experience, are the principles of the treatment of acute reactions of vulva and vagina. The topical use of estrogen, which promotes proliferation of epithelium, is generally described in connection with treatment and prophylaxis of late radiation injuries. As a prophylaxis for the late reaction of vaginal stenosis, vaginal dilatation is recommended in literature. Conclusion: With the exception of a few reports on estrogen, there are no data about the effectiveness of the currently used medical substances. The local application of estrogen as prophylaxis of the acute reactions will therefore be examined in a prospective study. (orig.) [Deutsch] Hintergrund: Akute und spaete Reaktionen an Vulva und Vagina sind haeufige und zum Teil schwerwiegende Nebenwirkungen der Strahlentherapie von gynaekologischen Tumoren, auf die in der Literatur kaum eingegangen wird. Methoden: Basierend auf einer umfangreichen Literaturrecherche, werden die Massnahmen, die zur Prophylaxe oder Therapie dieser Strahlenreaktionen zur Verfuegung stehen, systematisch zusammengestellt und, soweit verfuegbar, mit Ergebnissen aus Studien diskutiert. Ergebnisse: Hygienemassnahmen und die auf klinischen Erfahrungswerten basierende lokale Anwendung einer Vielzahl von mehr oder weniger antimikrobiell wirkenden oder granulationsfoerdernden Substanzen lassen sich als Grundprinzipien der Behandlung von akuten

  5. Management of radiation injuries of vulva and vagina

    Background: Acute and late injuries of vulva and vagina are frequent and potentially serious complications in radiotherapy of gynecologic tumors. They still are reported poorly in literature. Methods: Based on a literature search a survey will be given of the modalities, which are used or recommended for prophylaxis or treatment of these radiation injuries. The principles of the different measures will be discussed with available study results. Results: Hygiene measures and the topical application of antimicrobial or granulation stimulating substances, which is mostly based on long standing clinical experience, are the principles of the treatment of acute reactions of vulva and vagina. The topical use of estrogen, which promotes proliferation of epithelium, is generally described in connection with treatment and prophylaxis of late radiation injuries. As a prophylaxis for the late reaction of vaginal stenosis, vaginal dilatation is recommended in literature. Conclusion: With the exception of a few reports on estrogen, there are no data about the effectiveness of the currently used medical substances. The local application of estrogen as prophylaxis of the acute reactions will therefore be examined in a prospective study. (orig.)

  6. Normal tissue tolerance to external beam radiation therapy: The vagina

    The vagina is a virtual cavity involved in sexual reproduction field. Due to its anatomical location, it may be exposed in whole or in part to ionizing radiation in external radiotherapy and/or brachytherapy of the pelvic region. This review aims to describe the vaginal acute and late side effects due to radiation, probably inadequately reported in the literature. Medline and PubMed literature searches were performed using the keywords -vaginal - radiotherapy - toxicity. The acute and late functional changes after external beam radiation consist mainly of drought. Their incidences are poorly described in the literature and the delivered doses even less. Recommendations are non-existent as the normal tissue complication probability (NTCP). Brachytherapy delivers high and heterogeneous doses, making it difficult to estimate the dose. The concomitant administration of chemotherapy appears to be a factor increasing the risk of toxicity. Modern techniques of conformal radiotherapy with modulated intensity appear to have little impact on this body. Only a maximum dose on each third of the vagina appears to be currently proposed to avoid the risk of side effects. (authors)

  7. A longitudinal study of Staphylococcus hyicus colonization of vagina of gilts and transmission to piglets

    Wegener, Henrik Caspar; Skov Jensen, E.W.

    1992-01-01

    typing, as well as characterization of about 10 % of the isolates by plasmid profiles and antibiogram patterns, showed that, several different clones of S. hyicus could be present simultaneously in vagina of gilts and also on skin of piglets. Generally isolates from the vagina of one animal were...

  8. Malignant melanoma of the vagina: a report of 2 cases

    Kim, Ok Bae; Kim, Jin Hee; Jung, Young Yeon; Cho, Chi Heum; Choi, Tae Jin [Dongsan Medical Center, School of Medicine, Keimyung University, Daegu (Korea, Republic of)

    2005-06-15

    Primary malignant melanoma of the vagina is an extremely rare genital neoplasm occurring mainly in postmenopausal women. It has a worse prognosis than cutaneous melanomas, because of the high rate of locoregional recurrences and rapid systemic dissemination. In the past, radical surgical extirpation as the primary management had been recommended to improve loco-regional control, and possibly overall survival. However, the prognosis was poor in spite of such a radical approach. Recently, more conservative treatment such as wide local excision combined with adjuvant high-dose fraction radiotherapy seems to have promising results. Primary radiation therapy could be served as an alternative to surgery for patients with lesion less than 3 cm in diameter. We report 2 cases of primary vaginal malignant melanoma treated with radiotherapy.

  9. Surgical Management of the Constricted or Obliterated Vagina.

    Gebhart, John B; Schmitt, Jennifer J

    2016-08-01

    Management of the constricted or obliterated vagina demands an understanding and recognition of the potential etiologies leading to this presentation. A thorough and comprehensive medical and surgical review is required to arrive at an accurate diagnosis, which then will guide medical or surgical intervention. It is paramount to recognize when underlying medical conditions are contributing to these conditions and to begin medical therapy; failure to do so will often yield suboptimal results. When these conditions arise after surgical interventions, compensatory surgical techniques that correct upper and lower vaginal strictures or obliteration include incision through the stricture, vaginal advancement, Z-plasty, skin grafts, perineal flaps, and abdominal flaps and grafts. Postoperative surveillance and dilation are critical to optimize long-term success. PMID:27399991

  10. Radiation-induced morphological changes in the vagina

    Kirchheiner, K.; Fidarova, E.; Schmid, M.P.; Sturdza, A.; Kranz, A.; Poetter, R. [Medical Univ. of Vienna (Austria). Dept. of Radiation Oncology; Nout, R.A. [University Medical Center Leiden (Netherlands). Dept. of Clinical Oncology; Wiebe, E. [Alberta Univ., Cross Cancer Institute, Edmonton, AB (Canada). Dept. of Radiation Oncology; Polterauer, S. [Medical Univ. of Vienna (Austria). Dept. of General Gynecology and Gynecologic Oncology; Doerr, W. [Medical Univ. of Vienna (Austria). Dept. of Radiation Oncology; Medical Univ. of Vienna (Austria). Christian Doppler Laboratory for Medical Radiation Research for Radiation Oncology

    2012-11-15

    Background and purpose: Treatment-induced chronic vaginal changes after definitive radio(chemo)therapy for locally advanced cervical cancer patients are reported as one of the most distressing consequences of treatment, with major impact on quality of life. Although these vaginal changes are regularly documented during gynecological follow-up examinations, the classic radiation morbidity grading scales are not concise in their reporting. The aim of the study was therefore to identify and qualitatively describe, on the basis of vaginoscopies, morphological changes in the vagina after definitive radio(chemo)therapy and to establish a classification system for their detailed and reproducible documentation. Patients and methods: Vaginoscopy with photodocumentation was performed prospectively in 22 patients with locally advanced cervical cancer after definitive radio(chemo)therapy at 3-24 months after end of treatment. All patients were in complete remission and without severe grade 3/4 morbidity outside the vagina. Results: Five morphological parameters, which occurred consistently after treatment, were identified: mucosal pallor, telangiectasia, fragility of the vaginal wall, ulceration, and adhesions/occlusion. The symptoms in general were observed at different time points in individual patients; their quality was independent of the time of assessment. Based on the morphological findings, a comprehensive descriptive and semiquantitative scoring system was developed, which allows for classification of vaginal changes. A photographic atlas to illustrate the morphology of the alterations is presented. Conclusion: Vaginoscopy is an easily applicable, informative, and well-tolerated procedure for the objective assessment of morphological vaginal changes after radio(chemo)therapy and provides comprehensive and detailed information. This allows for precise classification of the severity of individual changes. (orig.)

  11. Particles translocate from the vagina to the oviducts and beyond

    Wehner, A.P.; Hall, A.S.; Weller, R.E.; Lepel, E.A.; Schirmer, R.E.

    1985-03-01

    To investigate whether particles deposited in the vagina translocate to the oviducts, 0.3 ml of a 4% bone black suspension was deposited in the posterior vaginal fornix of each of five cynomolgus monkeys (Macaca fascicularis) during their mid-menstrual cycle. Simultaneously, each animal received 10 units of oxytocin by intramuscular injection. The oviducts of three animals were removed 1 hr after administration of the bone black, while those of the remaining two animals were removed 72 hr after dosing. The removed oviducts were flushed with Hank's solution and then with collagenase solution. The solutions were collected in clean vials and filtered. The filters were examined for bone black particles by light microscopy, as were filters through which solution blanks (negative controls) had been passed. Particles resembling bone black were found on all filters. There were no appreciable differences in the number or shape of these particles between the solution-blank filters and the oviduct-flush filters. The particles on both the solution-blank filters and on the oviduct-flush filters probably originated from environmental contamination by ubiquitous carbon particles. While these results suggested that no translocation took place, translocation could not be ruled out with certainty in the absence of quantitative analyses. A more definitive pilot study was then conducted with two dosed monkeys and one control, using talc labelled by neutron activation to circumvent the problem of environmental contamination. Gamma-Ray analysis of tissue and peritoneal lavage samples for the radionuclides /sup 46/Sc, /sup 59/Fe and /sup 60/Co indicated that no measurable quantities (i.e. greater than 0.5 micrograms) of talc translocated from the deposition site in the vagina to the uterine cavity and beyond.

  12. Colocolpopoiesis : the use of sigmoid colon in the treatment of conditions associated with absence of the vagina

    I. Freundt (Ingrid)

    1994-01-01

    textabstractThe creation of a coitally functional vagina is an important part of sexual rehabilitation in patients with congenital or acqnired absence of the vagina, and in male-to-female transsexuals. Various conservative and surgical techniques have been developed to construct an artificial vagina

  13. High-dose-rate brachytherapy for cervical carcinoma patients with narrow vagina

    Yorozu, Atsunori; Toya, Kazuhito; Kawase, Takatugu [National Tokyo Medical Center, Tokyo (Japan); Dokiya, Takushi [Saitama Medical Coll., Moroyama (Japan)

    2002-06-01

    We retrospectively analyzed cervical cancer patients with narrow vagina treated by high-dose-rate (HDR) brachytherapy followed by external beam irradiation. Fifty patients were treated with radical radiotherapy between 1992 and 1999 at the National Tokyo Medical Center. All patients received 30 Gy of external whole pelvic irradiation and 20 Gy of pelvic irradiation with a central shield. After 30 Gy of whole pelvic irradiation, 24 Gy of fractionated brachytherapy was applied with a tandem and ovoids, non-rigid type developed in the Cancer Institute, according to the Manchester method. Nineteen patients with a narrow vagina of less than 40 mm in width were compared with 31 other patients (control group). The 5-year cumulative survival rates were 56% in the patients with a narrow vagina and 53% in the control group (P=0.6008). The control rate in the pelvis was not significantly different between the two groups. The cumulative rate of rectal complications of the patients with a narrow vagina was more frequent than the control group (58% vs 29%) (P=0.0924). Severe rectal bleeding was also more frequent in the patients with a narrow vagina. The estimated maximal dose of the rectal wall was significantly higher in patients with a narrow vagina. This result suggests that a lower brachytherapy dose is necessary for patients with narrow vagina considering the rectal sequelae in the case of using our methods. (author)

  14. Carcinoma of vagina 10 or more years following pelvic irradiation therapy

    Gynecologic cancer records of 4,238 patients treated between 1956 and 1974 were reviewed. Sixteen patients developed neoplasia in the cervix or vagina 10 or more years following pelvic irradiation. Three patients had squamous carcinoma in situ; the other 13 patients had invasive squamous cancer involving the upper vagina. Only 1.26 percent of invasive carcinoma of the cervix treated by radiation therapy from 1956 to 1966 presented with a late or recurrent or new primary tumor involving the vagina or cervix 10 or more years after primary treatment. The authors conclude that the risk of developing radiation-induced carcinoma in the upper vagina or cervix following pelvic irradiation is low. Follow-up Pap smears are indicated for all patients treated for cervical or vaginal malignancies by radiation therapy in order to detect vaginal neoplasia as well as recurrent carcinoma of the cervix

  15. Exclusive radiotherapy for primary squamous cell carcinoma of the vagina

    Purpose: To retrospectively analyze results of external beam therapy (EBT) with brachytherapy (BT) for primary vaginal squamous cell carcinoma (PVSCC). Materials and methods: From 1970 to 2001, 91 patients were included. FIGO stages were: I (29%), II (38%), III (29%) and IVa (4%). EBT delivered a median total dose of 50 Gy to the pelvis. BT was performed with a customized intra-vaginal applicator and in 36% of applications combined endocavitary and interstitial BT. ICRU Report 38 parameters were reported. Results: The 5-year cause specific survival (CSS) rates were: 83% for stage I, 76% for stage II, 52% for stage III, and 2 of the 4 stage IVa patients died 9 and 36 months after treatment. The 5-year pelvis control rates were: 79% for stage I and II and 62% for stage III. Recurrences as a first event were local only in 68% of cases, nodal only in 10%, metastatic only in 13% and combined in 9%. In multivariate analysis: stage (I and II versus II and IV), response to EBT (evaluated at BT), and the number of BT applications were statistically significant for CSS. Grade 2-3 toxicities were as follows (Franco-Italian Glossary): rectum (n = 3), sigmoid colon and small bowel (n = 8), bladder (n = 5), ureter (n = 4) and vagina (n = 13). Anterior location of the tumor increased bladder toxicity (p = 0.01) and total reference air kerma was higher in patients who experienced grade 2-3 urinary or digestive toxicity (p = 0.03). Conclusion: EBT with BT is an effective treatment for patients with stage I-II PVSCC. The incidence and severity of late toxicity were relatively low. Recent advances in the treatment of cervix carcinoma emphasize the need for concomitant radio-chemotherapy in stages III-IV and the use of MRI for treatment planning

  16. Sensibility of vagina reconstructed by McIndoe method in Mayer-Küster-Rokitansky-Hauser syndrome

    Vesanović Svetlana; Panajotović Ljubomir; Garalejić Elijana

    2008-01-01

    Background/Aim. Congenital absence of vagina is a failure present in Mayer-Küster-Rokitansky-Hauser syndrome. Treatment of this anomaly includes nonoperative and operative procedures. McIndoe procedure uses split skin graft by Thiersch. The aim of this study was to determine sensitivity (touch, warmness, coldness) of a vagina reconstructed by McIndoe method in Mayer-Küster-Rokitansky-Hauser syndrome and compare it with the normal vagina. Methods. A total of 21 female persons with reconstructe...

  17. Non-Diethylstilbestrol-Associated Primary Clear Cell Carcinoma of the Vagina: Two Case Reports with Immunohistochemical Studies and Literature Review

    Shagufta T. Mufti; Hiba Hassan Ali

    2015-01-01

    Primary clear cell adenocarcinomas most commonly involve the genitourinary system, including the vagina. Previously, primary clear cell adenocarcinomas of the vagina have been discussed within the context of prenatal exposure to diethylstilbestrol. Due to its widely proven role in the development of this carcinoma, administration of diethylstilbestrol is prohibited. We present two cases of non-diethylstilbestrol-associated primary clear cell adenocarcinoma of the vagina from the archives of t...

  18. Endodermal sinus tumor of the vagina in children: a report of two cases.

    Gangopadhyay, Mimi; Raha, Kalpana; Sinha, Swapan K; De, Anuradha; Bera, Pranati; Pati, Shyamapada

    2009-01-01

    Malignant tumors of the vagina in infants and children are rare, with primary germ cell tumor (endodermal sinus tumor [EST]) being rarer, which carries a dismal prognosis. This tumor is often clinically mistaken as botryoid rhabdomyosarcoma and, on histopathological examination, is often misdiagnosed as clear cell adenocarcinoma. Two cases of EST of the vagina in infants aged 9 and 17 months are reported. Both the patients presented with bleeding per vagina and clinically and by ultrasonography were diagnosed as sarcoma botryoides. Both were diagnosed as primary yolk sac tumors. The serum alfa fetoprotein (AFP) level was 4325 and 9328 ng/ml, respectively. One patient aged 9 months expired 2 months after receiving chemotherapy. The other, aged 17 months, was given chemotherapy followed by surgery with reduction of the AFP levels. PMID:19679975

  19. Ultrastructural characteristics of the vaginae of the basal monogenean Chimaericola leptogaster (Leuckart, 1830).

    Poddubnaya, Larisa G; Hemmingsen, Willy; Gibson, David I

    2013-12-01

    In the first study of the vaginal ultrastructure of any monogenean, the paired vaginae of Chimaericola leptogaster, a basal polyopisthocotylean from the gills of a holocephalan, are described. Each vagina opens laterally. A unique feature of this relict parasite is a short vagino-intestinal connecting duct, the lining of which is separated by septate junctions from the linings of the vagina and the intestine. After giving rise to this vagino-intestinal duct, each vagina travels in a posterior direction and opens into the vitelline collecting duct. The lining of each vagina close to the vaginal pore resembles the body tegument, the syncytial lining of which measures about 2.5 μm in thickness and has a dense surface layer 0.2 μm in thickness and different apical projections. Proximal to this and before the entrance to the vaginal-intestinal duct, the vaginal lining is characterised by: uniformly distributed electron-dense, lanceolate, spine-like surface structures of about 1.7 μm in length; three kinds of surrounding glands with three kinds of secretory granules (abundant oval or rounded electron-dense granules 0.7-2.5 μm in length, much less numerous spheroidal, vesicular granules 0.3-0.4 μm in diameter, and tightly packed, spheroidal granules 0.8 μm in diameter and containing fine particulate material of low density); and four kinds of sensory receptors (three uniciliate and one aciliate). These features are absent from the rest of the vagina. The likely roles of the vagino-intestinal connection, the different gland cells, sensory structures, and the armament of the distal vaginal regions are discussed. Considering the suggested polyopisthocotylean ancestor for the Neodermata, the relict parasite fauna of holocephalans and the unique vagino-intestinal connection in C. leptogaster, which is also known in turbellarians, an ancient origin for chimaericolids is supported. PMID:24043615

  20. Imaging of the vagina and vulva; Aspectos de imagem das lesoes vulvo-vaginais

    Souza, Luis Ronan Marquez Ferreira de; Szejnfeld, Jacob [Universidade Federal de Sao Paulo (UNIFESP/EPM), SP (Brazil). Dept. de Diagnostico por Imagem]. E-mail: luisronan@gmail.com; Borges, Leonardo Romualdo; Rosalen Junior, Roberto Antonio [Universidade Federal do Triangulo Mineiro (UFTM), Uberaba, MG (Brazil); Signorini Filho, Roney Cesar; Marques, Renato Moretti; Nicolau, Sergio Mancini [Universidade Federal de Sao Paulo (UNIFESP/EPM), SP (Brazil). Disciplina de Oncoginecologia; Goldman, Suzan Menasce [Universidade Federal de Sao Paulo (UNIFESP/EPM), SP (Brazil). Dept. de Diagnostico por Imagem

    2006-10-15

    In gynecological daily practices, the vulva and vagina are examined during physical examination, however there are situations where this is not possible or it is needed to determine the extension of an injury through imaging methods. The magnetic resonance imaging is an excellent cross-sectional modality for evaluation the alterations of vulva and vagina due its multiplanar evaluation and high tecidual contrast. Other cross-sectional modalities are ultrasound and enhanced computed tomography. This paper intends to give an overview of vaginal and vulvar pathology that can be identified by the radiologist. (author)

  1. Carcinoma of the vulva and vagina in patients irradiated for carcinoma of the cervix

    Six patients with carcinoma of the vulva and 3 with carcinoma of the vagina following radiation therapy for cancer of the cervix were analyzed. The interval between irradiation and diagnosis of the second tumor varied from 5 to 23 years. Despite the lack of having detailed information on irradiation factors in all patients, circumstantial evidence from this study suggests that radiation therapy may have contributed to the development of carcinoma of the vulva and vagina in some of the patients. Close follow-up patients treated for squamous carcinoma of the genital tract must emphasize inspection for new lesions. The incidences previously reported in the literature are also reviewed for comparison. (author)

  2. Carcinoma of the vulva and vagina in patients irradiated for carcinoma of the cervix

    Tsukiyama, Iwao; Kakehi, Masae; Ono, Ryosuke; Watai, Kiichi; Yanagawa, Shigeo; Kasamatsu, Tatsuhiro

    1984-08-01

    Six patients with carcinoma of the vulva and 3 with carcinoma of the vagina following radiation therapy for cancer of the cervix were analyzed. The interval between irradiation and diagnosis of the second tumor varied from 5 to 23 years. Despite the lack of having detailed information on irradiation factors in all patients, circumstantial evidence from this study suggests that radiation therapy may have contributed to the development of carcinoma of the vulva and vagina in some of the patients. Close follow-up patients treated for squamous carcinoma of the genital tract must emphasize inspection for new lesions. The incidences previously reported in the literature are also reviewed for comparison. (author).

  3. Committee Opinion No. 571: Solutions for surgical preparation of the vagina.

    2013-09-01

    Currently, only povidone-iodine preparations are approved for vaginal surgical-site antisepsis. However, there are compelling reasons to consider chlorhexidine gluconate solutions for off-label use in surgical preparation of the vagina, especially in women with allergies to iodine. Although chlorhexidine gluconate solutions with high concentrations of alcohol are contraindicated for surgical preparation of the vagina, solutions with low concentrations of alcohol (eg, 4%) are both safe and effective for off-label use as vaginal surgical preparations and may be used as an alternative to iodine-based preparations in cases of allergy or when preferred by the surgeon. PMID:23963423

  4. Safety, Efficiency, and Outcomes of Perineoplasty: Treatment of the Sensation of a Wide Vagina.

    Ulubay, Mustafa; Keskin, Ugur; Fidan, Ulas; Ozturk, Mustafa; Bodur, Serkan; Yılmaz, Ali; Kinci, Mehmet Ferdi; Yenen, Mufit Cemal

    2016-01-01

    Background. The sensation of a wide vagina is a common problem for women after childbirth. As its etiology is unknown, there is no uniform management strategy. We hypothesized that, rather than vaginal laxity, the cause was level 3 pelvic support deficiency. Methods. This retrospective study compared preoperative and postoperative genital hiatus length, perineal length, and total vaginal length in patients treated with perineoplasty for the sensation of a wide vagina. A telephone survey was used to determine postoperative patient and male partner satisfaction rates. Results. Mean age of patients was 48 (26-68) years; mean body mass index (BMI) was 25.3 (17.6-33.2); and mean parity was 2.5 (2-5). Preoperative and postoperative genital hiatus, perineal length, and total vaginal length were 4.62 and 3.18 (p vagina. Conclusion. With low dyspareunia rates, low complication rates, high patient satisfaction, and satisfactory anatomical success, perineoplasty can be considered successful for treatment of the sensation of a wide vagina. PMID:27610368

  5. A RARE CASE OF PRIMARY MALIGNANT MELANOMA OF THE VAGINA IN A YOUNG LADY: A REPOR

    Sangeeta

    2013-10-01

    Full Text Available ABSTRACT : Malignant melanoma of vagina is a rare tumor with incidence rate of only 0.46 c ases per one million women per year and less than 250 cases have been reported in medical literature till date. It has a notoriously aggressive behavior and is associated with a high risk of local recurrence and distant metastasis. At present, there are va rious treatment options for this disease but no standard guideline. It accounts for less than 1% of all malignant melanoma and less than 3% of all primary malignant tumors of the vagina. Conventional imaging techniques i.e. computed tomography, may be sub - optimal in evaluating a small volume of tumor, which may lead to inaccurate staging of a loco - regional tumor . The optimal treatment for vaginal melanoma is a subject of debate. Malignant melanoma of the vagina is a disease of postmenopausal women, with 75 % of women being more than 50 years of age . Here, we present a case of primary vaginal malignant melanoma in a 35 year woman located in lower 1/3 rd of the vagina

  6. Hematocolpos in double vagina associated with uterus didelphus: US and MR findings

    Ballesio, L.; Andreoli, C.; De Cicco, M.L.; Angeli, M.L.; Manganaro, L

    2003-02-01

    The malformative syndrome of double vagina in association with uterus didelphus and kidney agenesis is a rare condition, often asymptomatic: if this condition is accompanied by imperforated obstructed hemivagina, the clinical manifestations depend on the presence of hematocolpos. MRI plays an important role for diagnosis because it allows to characterize the nature of the lesion and to evaluate the anatomical details of the uterine malformation. The authors describe this complex genital malformation and discuss the main US and MRI features.

  7. Measuring the space between vagina and rectum as it relates to rectocele

    Jin Liu; Li-Dong Zhai; Yun-Sheng Li; Wan-Xiang Liu; Rui-Hua Wang

    2009-01-01

    AIM: To measure the normal space between the posterior wall of the vagina and the anterior wall of the respectively rectum using computed tomography (CT) and reveal its were relationship to rectocele. METHODS: A total of twenty female volunteers without rectocele were examined by CT scan. We performed a middle level continuous horizontal pelvic scan from the upper part to the lower part and collected the measurement data to analyze the results using t -test. RESULTS: Twenty volunteers were enrolled in the study. The space between the posterior wall of the vagina and the anterior wall of the rectum was measured at three levels (upper 1/3, middle, lower 1/3 level of vagina).The results showed that the space from the posterior wall of the vagina to the anterior wall of the rectum at the upper 1/3 level and the middle level was 3.896 ± 0.3617 mm and 4.6575 ± 0.3052 mm, respectively. When the two groups of data were compared, we found the space at the upper 1/3 level was shorter than at the middle level (P < 0.01). Moreover, at the lower 1/3 level the space measured was 10.058 ± 0.4534 mm. The results revealed that the space at the lower 1/3 level was longer than that at the middle level (P < 0.01). CONCLUSION: These measurement data may be helpful in assessing rectocele clinical diagnosis and functional outcomes of rectocele repair.

  8. Long-term results of radiotherapy in primary carcinoma of the vagina

    Hegemann, Stefan; Willich, Normann [University Hospital, Muenster (Germany). Dept. of Radiotherapy and Radiation Oncology; Schaefer, Ulrich [University Hospital, Muenster (Germany). Dept. of Radiotherapy and Radiation Oncology; Lippe Hospital, Lemgo (Germany). Dept. of Radiotherapy; Lelle, Ralph [University Hospital, Muenster (Germany). Dept. of Gynecology and Gynecologic Oncology; Micke, Oliver [University Hospital, Muenster (Germany). Dept. of Radiotherapy and Radiation Oncology; Franziskus Hospital, Bielefeld (Germany). Dept. of Radiotherapy and Radiation Oncology

    2009-03-15

    Background: The long-term results of radiotherapy in primary carcinoma of the vagina are not well defined. Patients and Methods: The treatment results of 41 patients with primary malignancies of the vagina were analyzed. The mean follow-up period was 77.3 months (2.3-404 months). The predominant histology was squamous cell carcinoma, FIGO stages I: n = 7 (17.1%), II: n = 13 (31.7%), III: n = 13 (31.7%), and IVa: n = 8 (19.5%). Radiotherapy was the primary treatment for all patients. None of the patients had undergone prior surgery for vaginal carcinoma. The majority of patients received pelvic irradiation, including treatment of the inguinal lymphatics (median dose: 50 Gy). 26 patients received additional intravaginal brachytherapy. Results: Overall, 21 patients (51.2%) achieved complete remission, 17 patients (41.5%) had partial responses, and three patients (7.3%) had no change or progressive disease. The total median survival of the analyzed patients was 41.3 months. The 1-year survival probability was 85.4%, the 5-year survival probability 40.6%, and the 10-year survival probability 27.2%. Univariate analysis revealed a survival advantage for earlier tumor stages (FIGO I and II) compared to advanced stages (FIGO III and IV), with a median survival of 58.1 months compared to 26.8 months. Treatment side effects were tolerable and easily managed. Conclusion: Definite radiotherapy is the treatment of choice for primary carcinomas of the vagina. Considering that primary malignancies of the vagina are typically diseases of the elderly, it should be noted that radiotherapy is especially well tolerated in this population. (orig.)

  9. CT and MR imaging findings of primary leiomyosarcoma of the vagina : a case report

    Cho, So Hee; Rha, Sung Eun; Cho, Song Mee; Byun, Jae Young [College of Medicine, The Catholic Univ. of Korea, Seoul (Korea, Republic of)

    2001-09-01

    Primary malignant lesions of the vagina are uncommon and represent approximately 1-2% of all gynecologic malignancies. About 2% of all malignant vaginal lesions are primary sarcomas, the most common of these being leiomyosarcoma. We report the CT and MR imaging findings in a 41-year-old woman with vaginal leiomyosarcoma presenting as a bulky solid mass which caused expansion of the vaginal canal.

  10. Regional variation in tissue composition and biomechanical properties of postmenopausal ovine and human vagina.

    Daniela Ulrich

    Full Text Available OBJECTIVE: There are increasing numbers of reports describing human vaginal tissue composition in women with and without pelvic organ prolapse with conflicting results. The aim of this study was to compare ovine and human posterior vaginal tissue in terms of histological and biochemical tissue composition and to assess passive biomechanical properties of ovine vagina to further characterise this animal model for pelvic organ prolapse research. STUDY DESIGN: Vaginal tissue was collected from ovariectomised sheep (n = 6 and from postmenopausal women (n = 7 from the proximal, middle and distal thirds. Tissue histology was analyzed using Masson's Trichrome staining; total collagen was quantified by hydroxyproline assays, collagen III/I+III ratios by delayed reduction SDS PAGE, glycosaminoglycans by dimethylmethylene blue assay, and elastic tissue associated proteins (ETAP by amino acid analysis. Young's modulus, maximum stress/strain, and permanent strain following cyclic loading were determined in ovine vagina. RESULTS: Both sheep and human vaginal tissue showed comparable tissue composition. Ovine vaginal tissue showed significantly higher total collagen and glycosaminoglycan values (p<0.05 nearest the cervix. No significant differences were found along the length of the human vagina for collagen, GAG or ETAP content. The proximal region was the stiffest (Young's modulus, p<0.05, strongest (maximum stress, p<0.05 compared to distal region, and most elastic (permanent strain. CONCLUSION: Sheep tissue composition and mechanical properties showed regional differences along the postmenopausal vaginal wall not apparent in human vagina, although the absolute content of proteins were similar. Knowledge of this baseline variation in the composition and mechanical properties of the vaginal wall will assist future studies using sheep as a model for vaginal surgery.

  11. Placement of temperature probe in bovine vagina for continuous measurement of core-body temperature

    Lee, C. N.; Gebremedhin, K. G.; Parkhurst, A.; Hillman, P. E.

    2015-09-01

    There has been increasing interest to measure core-body temperature in cattle using internal probes. This study examined the placement of HOBO water temperature probe with an anchor, referred to as the "sensor pack" (Hillman et al. Appl Eng Agric ASAE 25(2):291-296, 2009) in the vagina of multiparous Holstein cows under grazing conditions. Two types of anchors were used: (a) long "fingers" (4.5-6 cm), and (b) short "fingers" (3.5 cm). The long-finger anchors stayed in one position while the short-finger anchors were not stable in one position (rotate) within the vagina canal and in some cases came out. Vaginal temperatures were recorded every minute and the data collected were then analyzed using exponential mixed model regression for non-linear data. The results showed that the core-body temperatures for the short-finger anchors were lower than the long-finger anchors. This implied that the placement of the temperature sensor within the vagina cavity may affect the data collected.

  12. Fractionated stereotactic radiotherapy with vagina carotica protection technique for local residual nasopharyngeal carcinoma after primary radiotherapy

    LIU Feng; HUAN Fu-kui; FANG Hao; WAN Bao; LI Ye-xiong; XIAO Jian-ping; XU Ying-jie; ZHANG Ye; XU Guo-zhen; GAO Li; YI Jun-lin; LUO Jing-wei; HUANG Xiao-dong

    2012-01-01

    Background Local failure of nasopharyngeal carcinoma (NPC) after radiotherapy (RT) remains one of the major treatment failures.This study aimed to evaluate the clinical efficacy and complications of fractionated stereotactic radiotherapy (FSRT) with vagina carotica protection technique for local residual of NPC patients after the primary RT.Methods From August 2006 to August 2010,FSRT with vagina carotica protection technique was applied to 36 patients in our department,the patients aged between 13 and 76 years with a median of 41.3 years,25 of them were male and 11were female.According to 2002 Union for International Cancer Control (UICC) Staging System,the stages before primary radiotherapy were:Ⅱa 2,Ⅱb 5,Ⅲ 18,Ⅳa 7,Ⅳb 4.In the first course of radiotherapy,9 patients received conventional RT,27 patients received intensity modulated radiotherapy (IMRT) and 20 out of the 36 patients received concurrent chemoradiotherapy.The total dose in the first course of RT was 69.96-76.90 Gy (median,72.58 Gy).The intervals between the primary RT and FSRT ranged from 12 to 147 days (median,39.8 days).Target volumes ranged from 1.46 to 32.98 cm3 (median,14.94 cm3).The total FSRT doses were 10.0-24.0 Gy (median,16.5 Gy) with 2.0-5.0Gy per fraction.The most common regimen was 15 Gy in 5 fractions of 3 Gy,the irradiation dose to vagina carotica was less than 2 Gy per fraction.Results The median follow-up time was 34 months (range,12-59 months).The 3-year local control rate was 100%;the 3-year overall survival rate was 94.4%;the 3-year disease-free survival rate was 77.8%.In this study,we had one case of cranial nerve injury,two cases of temporal lobe necrosis,and no nasopharyngeal massive hemorrhage was observed.Conclusion FSRT with vagina carotica protection technique is an effective and safe RT regimen for local residual of NPC with reduction of radiation-related neurovascular lesions.

  13. Borderline malignant change in recurrent müllerian papilloma of the vagina.

    Dobbs, S P; Shaw, P A; Brown, L J; Ireland, D.

    1998-01-01

    Malignant change occurred in a benign, recurrent vaginal müllerian polyp. The patient, a 49 year old woman with cerebral palsy, presented with a polypoid mass in the vagina. At four years of age she had presented with a haemorrhagic polyp, and over the following years she had recurrent irregular bleeding and regrowth of the polypoidal mass, requiring a total of 10 operations to excise the polyp. Histological examination of the specimen showed typical müllerian features with tubal, endometrioi...

  14. Putting Women Back on Top?: (Re)constituting Power and Audience in The Vagina Monologues

    Gellert, Ashley Elizabeth

    2011-01-01

    Eve Enslerâ s goal in writing The Vagina Monologues was to generate a dialogue regarding womenâ s sexuality to counter the silence that pervades the patriarchal culture that they inhabit. To achieve this goal, Ensler constructs two ideologiesâ one grounded in patriarchy and another supposedly grounded in female agency and dialogueâ to reveal the problems within the current ideology in hopes that her audience will adopt her new ideology and resolve the detrimental silence women endure. T...

  15. Tubulosquamous polyps in the vagina. Immunohistochemical comparison with ectopic prostatic tissue and Skene glands.

    Roma, Andres A

    2016-06-01

    Two tubulosquamous polyps arising in the vagina are reported. Both were diffusely positive for GATA3 in the squamous component and focally positive for NKX3.1 in the glandular component, prostate acid phosphatase was focally positive in only 1 case in the glandular component. Both cases were negative for PAX2, PAX8, SALL4, and prostate-specific antigen. In addition, we included 3 cases of cervical squamous-lined cysts most likely representing ectopic prostatic tissue in the cervix and 1 case of paraurethral Skene-type glands to compare the immunophenotype. We analyze this immunoprofile, not previously reported. We also suggest unifying the nomenclature because vaginal Brenner tumors are most likely synonymous with tubulosquamous polyp (TSP) of the vagina. Our findings add support to the postulated origin of TSPs and cervical ectopic prostatic tissue from eutopic or misplaced Skene glands, equivalent of the prostate in the female. NKX3.1 seems a better marker to study and diagnose ectopic prostatic tissue in the cervix as well as TSPs. PMID:27180063

  16. Radiation therapy for primary squamous cell carcinoma of the vagina: Stanford University experience

    A retrospective analysis of 38 patients with primary squamous cell carcinoma of the vagina seen at Stanford University Medical Center from 1958 to 1984 was undertaken. Patients were analyzed with regard to symptoms, stage, treatment techniques, survival, patterns of failure, and complications. Eighteen patients were classified as FIGO Stage I, 5 as Stage II, 10 as Stage III, and 5 as Stage IV. The 5-year disease-free survival was 94% in Stage I, 80% in Stage II, 50% in Stage III, and 0% in Stage IV. Five patients (13%) had eight major complications secondary to treatment. Only 2 of 23 patients with Stage I or Stage II disease developed a recurrence. There was a significant correlation between dose and response in patients treated with radiotherapy

  17. [Primary peripheral T-cell lymphoma of the vagina incidentally found at cervical cancer screening].

    Isobe, Rei; Mituishi, Toshimi; Omote, Mayuko; Mori, Yuichi; Ida, Koichi; Oguchi, Osamu; Nakai, Ikuko; Oguchi, Masahiko

    2016-01-01

    A 50-year-old woman was referred to our hospital because a mass lesion had been palpable through the vaginal wall during a cervical cancer screening examination. A contrast-enhanced computed tomography (CT) scan and magnetic resonance imaging (MRI) revealed marked thickening of the vaginal wall, constituting a mass 96 mm in diameter. Abnormal FDG uptake was observed in the vaginal mass, but no other lesions were detected by positron emission tomography (PET/CT). A transvaginal biopsy from the tumor revealed peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS). Although endoscopic examinations revealed no signs of infiltration in either the bladder or the rectum, the MRI findings suggested invasion into the adjacent rectal wall. She achieved complete remission after six courses of biweekly THP-COP therapy, to which field radiation (39.6 Gy) was added. PTCL of the vagina is rare and this case therefore merits description in the literature. PMID:26861099

  18. Radicality of initial surgery for primary malignant melanoma of the vagina.

    Todo, Yukiharu; Okamoto, Kazuhira; Suzuki, Yoshihiro; Minobe, Shinichiro; Kato, Hidenori

    2016-04-01

    Radical surgery is considered not to improve the prognosis of primary malignant melanoma of the vagina (PMMV). This study was carried out to review the general consensus. A systematic review was performed on the basis of data from 10 patients in our cohort and 147 patients in the previous literature. The radicality of the initial surgery (RAINS) score was defined as the total number of points in terms of the resected organs. The target organs were the vagina, vulva, urethra, bladder, uterus, anus, rectum, pelvic lymph nodes, and inguinal lymph nodes. Overall survival (OS) according to the RAINS score was analyzed using the Kaplan-Meier method. Information on tumor stage, size, and depth of invasion was not obtained in 15, 47, and 43% of patients, respectively. The median follow-up period was 18 months. OS with a RAINS score of at least 7 was significantly longer than that with a RAINS score of up to 6 (median survival time, 41 vs. 19 months; log-rank test, P=0.037), despite the fact that the former group included significantly more patients with advanced-stage disease. A significant difference in OS was not found between patients with a RAINS score of at least 6 and up to 5. The therapeutic significance of radical surgery for PMMV has not been assessed appropriately in previous studies because of the lack of comparability among groups and differences in the definitions of surgical radicality. Patients with PMMV might benefit from initial surgery with appropriate surgical radicality, despite incomplete validation of the RAINS score. PMID:26825038

  19. Absence of a vagina and right sided adnexa uteri in the Waardenburg syndrome: a possible clue to the embryological defect.

    Goodman, R M; Oelsner, G; Berkenstadt, M; Admon, D.

    1988-01-01

    An 18 year old single Jewish woman with the Waardenburg syndrome and absence of a vagina and right sided adnexa uteri is reported. Other congenital malformations associated with the Waardenburg syndrome are mentioned and it is postulated that they may be the result of an altered invasion of neurones or altered neurones in certain organ systems early in embryogenesis.

  20. De betrouwbaarheid van het vagina-uitstrijkje van de rat als middel om de fase van de bronstcyclus te detecteren

    van Velsen FL; Loeber JG; Franken MAM; Liefde AD

    1985-01-01

    De betrouwbaarheid van het vagina-uitstrijkje bij de rat als indicator van de fase van de cyclus is onderzocht bij 60 dieren van 250 g. Gedurende 4 achtereenvolgende weken is op de werkdagen een uitstrijkje gemaakt ter beoordeling van de regelmaat van de cyclus. Daarna zijn de dieren geseceerd na d

  1. Reconstruction of the anus, rectovaginal septum, and distal part of the vagina after postirradiation necrosis. Report of a unique case

    Successful repair of postirradiation total loss of the anal sphincters, rectovaginal septum, and distal part of the vagina is reported. Gracilis muscle flap was used as a substitute sphincter. Part of the muscle was wrapped-up in a split skin graft. To the authors' knowledge, this is the first report on new application of gracilis muscle and split skin graft in perineal reconstruction

  2. Complete Genome Sequence of Lactococcus lactis subsp. lactis CV56, a Probiotic Strain Isolated from the Vaginas of Healthy Women▿

    Gao, Yong; Lu, Ying; Teng, Kun-Ling; Chen, Mei-Ling; Zheng, Hua-Jun; Zhu, Yong-Qiang; Zhong, Jin

    2011-01-01

    Lactic acid bacteria that exist in the urinogenital system play an important role in maintaining the health of the host. Here, we report the finished and annotated genome of a Lactococcus strain that was isolated from the vaginas of healthy women and shows probiotic properties, including nisin A production and adhesion to vaginal epithelial cells.

  3. Perivascular epithelioid cell tumour of the vagina in an 8 year old girl.

    Ong, Lin Yin; Hwang, Wei Sek; Wong, Adelina; Chan, Mei Yoke; Chui, Chan Hon

    2007-03-01

    Perivascular epithelioid cell tumor (PEComa) is a rare mesenchymal tumor with an unpredictable natural history. We present the first reported case of PEComa of the vagina diagnosed in an 8-year-old girl. This was initially diagnosed on biopsy as an embryonal rhabdomyosarcoma, and the patient underwent 3 cycles of chemotherapy according to the Mesenchymal Malignant Tumour 1989 protocol. A repeat scan, however, revealed an increase in tumor size. Total resection was achieved via a transvaginal (vertical sleeve) partial vaginectomy. The resected tumor had the typical appearance of a PEComa. Immunostains showed positive staining of tumor cells for HMB45, neuron-specific enolase, and calponin but were negative for S100 protein, melaninA, chromogranin, smooth muscle actin, desmin, caldesmon, epithelial membrane antigen, AE1/3, and synaptophysin. Six months after surgery, she remains free of tumor and is on follow-up with regular local examinations under anesthesia and computed tomography scans. Our case highlights the importance of an accurate initial diagnosis, and we stress the importance of regular surveillance over a significant period. PMID:17336201

  4. [Streptococcus agalactiae (GBS)--the characteristic of isolated strains from productive women's vagina].

    Wolny, Katarzyna; Gołda-Matuszak, Ewa

    2010-01-01

    The main aim of my research: to determine the frequency of colonisation Streptococcus agalactiae from productive women's vagina, an evaluation of usefulness microbiological diagnostic methods to detect GBS, to define serotype of analysed strains of S. agalactiae. After all, I tried to define fenotypic differential, biochemical and antimicrobial susceptibility between GBS with and without hemolysis. All of strains S. agalactiae (n = 380) belong to bacteria Gram(+), they had B serologic group and didn't produce catalase. On the basis of TSA+5% sheep blood streptococcus with beta-hemolysis grew like a small, grey and shiny colonies with a narrow, bright ring. On the same base we had S. agalactiae without beta-hemolysis, in examine material--6% (n = 22). On the basis of Strepto B ID S. agalactiae grew like a small, round red colonies and on the base Granada agar like an orange, white colonies. The level of colonisation S. agalactiae was 22% (380GBS/1727women). Identification of analysed strains of S. agalactiae was made by test API 20 Strep. The susceptibility was examined to ampicilin, azithromycin, erythromycin, clindamycin, chloramphenicol, doxycyclin, cotrimoxasol, ciprofloxacin. Serotypes III (50%), Ia (18%) and V (14%) prevailed. PMID:20873487

  5. Recurrent paediatric pinworm infection of the vagina as a potential reservoir for Enterobius vermicularis.

    Kashyap, B; Samantray, J C; Kumar, S; Jhamb, R; Singh, A K; Kaur, I R

    2014-09-01

    Enterobius vermicularis infection remains one of the most common parasitic infections, particularly prevalent in children. Enterobiasis, although not usually dangerous, may cause significant morbidity. Elimination of the parasite from a family or an institution often poses problems, either because of an incomplete cure or re-infection. While there have been limited reports of ectopic enterobiasis throughout the world, ours is probably one of the rarest reports of recurrent vaginal E. vermicularis infection in the absence of any gastrointestinal symptoms despite complete treatment. A 4-year-old girl presented with recurrent episodes of vulval itching on 3-4 occasions over 2 years. There was no pruritis ani nor urinary/gastrointestinal complaints. The vulva was inflamed with 4-5 living worms, 6-7 mm in length, emerging from the anterior vaginal fornix, but with no vaginal discharge. Direct microscopic examination of vaginal swabs revealed adult worms of Enterobius but no eggs. Repeated stool samples from the patient, parents and a sibling were negative. The patient was treated orally with 100 mg of mebendazole for 3 days followed by two more courses at 3-week intervals over a period of 3 months. Recurrent vaginal enterobiasis despite complete treatment and in the absence of any gastrointestinal involvement suggests that the vagina is a potential reservoir for E. vermicularis, which supports the theory of rare ectopic enterobiasis through the ascending pathway of the female genital tract. PMID:23721910

  6. Estudio de micoplasmas y bacterias aerobias en la vagina craneal de hembras caninas clínicamente sanas

    Stornelli, María Alejandra; Cerdá, Raúl Oscar; Gobello, Cristina; Arauz, María Sandra; Stanchi, Néstor Oscar

    2000-01-01

    La flora bacteriana presente en la vagina de hembras caninas posee un discutido rol en las enfermedades reproductivas de esta especie, por lo tanto y para contribuir al esclarecimiento de este aspecto, se realizó un estudio de los microorganismos vaginales en 33 perras sanas. Las muestras fueron tomadas mediante hisopo cubierto y procesadas siguiendo las marchas bacteriológicas indicadas para bacterias aerobias y Micoplasmas. Se aislaron microorganismos a partir de 30 muestras, siendo 3 negat...

  7. A RARE C.T. SCAN FINDING OF FOREIGN BODY VAGINA, A HARD FRUIT, KEPT AS PESSARY FOR UTERINE PROLAPSE

    Radha Rani

    2014-06-01

    Full Text Available Vaginal pessaries still have a role in the management of uterine prolapse, particularly in elderly patients. The presence of a foreign body or device in the female pelvis can be a potential source of confusion to the radiologists, particularly to the inexperienced reader. We present a rare C.T. scan finding of a hard fruit kept in vagina 5yrs back for uterine prolapse.

  8. Characterisation of the bacterial microbiota of the vagina of dairy cows and isolation of pediocin-producing Pediococcus acidilactici

    Wang Yvonne; Ametaj Burim N; Ambrose Divakar J; Gänzle Michael G

    2013-01-01

    Abstract Background Uterine infections in dairy cows lower profitability of dairy operations. Infections of the reproductive tract are related to the overgrowth of pathogenic bacteria during the first three weeks after parturition. However, alterations in the vaginal microbiota composition in the first weeks after parturition remain poorly documented. Results In this study, bacteria isolated from the vagina of healthy pregnant, and infected postpartum cows were characterised by random amplifi...

  9. In vivo Raman spectroscopy of human uterine cervix: exploring the utility of vagina as an internal control

    Shaikh, Rubina; Dora, Tapas Kumar; Chopra, Supriya; Maheshwari, Amita; Kedar K., Deodhar; Bharat, Rekhi; Krishna, C. Murali

    2014-08-01

    In vivo Raman spectroscopy is being projected as a new, noninvasive method for cervical cancer diagnosis. In most of the reported studies, normal areas in the cancerous cervix were used as control. However, in the Indian subcontinent, the majority of cervical cancers are detected at advanced stages, leaving no normal sites for acquiring control spectra. Moreover, vagina and ectocervix are reported to have similar biochemical composition. Thus, in the present study, we have evaluated the feasibility of classifying normal and cancerous conditions in the Indian population and we have also explored the utility of the vagina as an internal control. A total of 228 normal and 181 tumor in vivo Raman spectra were acquired from 93 subjects under clinical supervision. The spectral features in normal conditions suggest the presence of collagen, while DNA and noncollagenous proteins were abundant in tumors. Principal-component linear discriminant analysis (PC-LDA) yielded 97% classification efficiency between normal and tumor groups. An analysis of a normal cervix and vaginal controls of cancerous and noncancerous subjects suggests similar spectral features between these groups. PC-LDA of tumor, normal cervix, and vaginal controls further support the utility of the vagina as an internal control. Overall, findings of the study corroborate with earlier studies and facilitate objective, noninvasive, and rapid Raman spectroscopic-based screening/diagnosis of cervical cancers.

  10. Antagonistic Potential against Pathogenic Microorganisms and Hydrogen Peroxide Production of Indigenous Lactobacilli Isolated from Vagina of Chinese Pregnant Women

    HENG-YI XU; WAN-HONG TIAN; CUI-XIANG WAN; LI-JUN JIA; LAN-YIN WANG; JING YUAN; CHUN-MEI LIU; MING ZENG; HUA WEI

    2008-01-01

    Objective To investigate the indigenous lactobacilli from the vagina of pregnant women and to screen the isolates with antagonistic potential against pathogenic microorganisms. Methods The strains were isolated from pregnant women's vagina and identified using the APISOCH system. The ability of the isolates to produce hydrogen peroxide was analyzed semi-quantitatively using the TMB-HRP-MRS agar. The antagonistic effects of the isolates on pathogenic microorganisms were determined with a double layer agar plate. Results One hundred and three lactobacilli strains were isolated from 60 samples of vaginal secretion from healthy pregnant women. Among them, 78 strains could produce hydrogen peroxide, in which 68%, 80%, 80%, and 88% had antagonistic effects against Candida albicans CMCC98001, Staphylococcus aureus CMCC26003, Escherichia coli CMCC44113, and Pseudomonas aeruginosa CMCC10110, respectively. Conclusion The recovery of hydrogen peroxide-producing lactobacilli decreases with the increasing pregnant age and time. The most commonly isolated species from vagina of Chinese pregnant women are Lactobacillus acidophilus and Lactobacillus crispatus. Most of L. Acidophilus and L. Crispatus produce a high H2O2 level.

  11. Delivery of double singleton pregnancies in a woman with a double uterus, double cervix, and complete septate vagina.

    Yang, Ming-Jie; Tseng, Jen-Yu; Chen, Chih-Yao; Li, Hsin-Yang

    2015-12-01

    Uterine anomalies involving a double uterus, double cervix, also known as didelphys uterus, and complete septate vagina are rarely seen and have an associated fertility problem. However, artificial reproductive technology with embryo transfers can help solve this fertility challenge. Conception in the uterus in just one side is commonly seen for embryos, which are always transferred through the usually used (dilated) vagina. We here present a patient with the above uterine anomaly who conceived with the aid of in vitro fertilization and embryo transfer to both uterine cavities under general anesthesia, which resulted in successful double singleton pregnancies with one fetus in each uterus. With intensive prenatal care, the pregnancy course for each fetus was rather uneventful. Although both fetuses were in cephalic presentation, cesarean section was performed at the 39(th) week of gestation with good outcomes in order to preclude anticipated difficulties if the baby had been delivered through the rarely dilated vagina. However, order of birth between the two fetuses was a crucial decision during the operation. PMID:26462956

  12. Effect of semen collection method (artificial vagina vs. electroejaculation), extender and centrifugation on post-thaw sperm quality of Blanca-Celtibérica buck ejaculates

    Jiménez Rabadán, Pilar; Ramón, Manuel; García Alvarez, Olga; Maroto Morales, Alejandro; Olmo, Enrique del; Pérez Guzmán, María Dolores; Bisbal, A.; Fernández Santos, María del Rocío; Garde López-Brea, José Julián; Soler, Ana Josefa

    2012-01-01

    The aim of this study was to evaluate the effect of semen collection method (artificial vagina compared to electroejaculation), season in which the semen was collected (breeding season compared to non-breeding season), freezing extender (Biladyl®, Andromed® and skim milk based extender) and pre-treatment procedure (washing compared to non-washing) on post-thaw semen quality in buck. Ejaculates from seven bucks of the Blanca-Celtibérica breed were collected by artificial vagina ...

  13. Unravelling the Bacterial Vaginosis-Associated Biofilm: A Multiplex Gardnerella vaginalis and Atopobium vaginae Fluorescence In Situ Hybridization Assay Using Peptide Nucleic Acid Probes

    Hardy, Liselotte; Jespers, Vicky; Dahchour, Nassira; Mwambarangwe, Lambert; Musengamana, Viateur; Vaneechoutte, Mario; Crucitti, Tania

    2015-01-01

    Bacterial vaginosis (BV), a condition defined by increased vaginal discharge without significant inflammation, is characterized by a change in the bacterial composition of the vagina. Lactobacillus spp., associated with a healthy vaginal microbiome, are outnumbered by BV-associated organisms. These bacteria could form a polymicrobial biofilm which allows them to persist in spite of antibiotic treatment. In this study, we examined the presence of Gardnerella vaginalis and Atopobium vaginae in ...

  14. Unravelling the Bacterial Vaginosis-Associated Biofilm: A Multiplex Gardnerella vaginalis and Atopobium vaginae Fluorescence In Situ Hybridization Assay Using Peptide Nucleic Acid Probes.

    Liselotte Hardy

    Full Text Available Bacterial vaginosis (BV, a condition defined by increased vaginal discharge without significant inflammation, is characterized by a change in the bacterial composition of the vagina. Lactobacillus spp., associated with a healthy vaginal microbiome, are outnumbered by BV-associated organisms. These bacteria could form a polymicrobial biofilm which allows them to persist in spite of antibiotic treatment. In this study, we examined the presence of Gardnerella vaginalis and Atopobium vaginae in vaginal biofilms using Peptide Nucleic Acid (PNA probes targeting these bacteria. For this purpose, we developed three new PNA probes for A. vaginae. The most specific A. vaginae probe, AtoITM1, was selected and then used in an assay with two existing probes, Gard162 and BacUni-1, to evaluate multiplex FISH on clinical samples. Using quantitative polymerase chain reaction (qPCR as the gold standard, we demonstrated a sensitivity of 66.7% (95% confidence interval: 54.5% - 77.1% and a specificity of 89.4% (95% confidence interval: 76.1% - 96% of the new AtoITM1 probe. FISH enabled us to show the presence of a polymicrobial biofilm in bacterial vaginosis, in which Atopobium vaginae is part of a Gardnerella vaginalis-dominated biofilm. We showed that the presence of this biofilm is associated with high bacterial loads of A. vaginae and G. vaginalis.

  15. Unravelling the Bacterial Vaginosis-Associated Biofilm: A Multiplex Gardnerella vaginalis and Atopobium vaginae Fluorescence In Situ Hybridization Assay Using Peptide Nucleic Acid Probes.

    Hardy, Liselotte; Jespers, Vicky; Dahchour, Nassira; Mwambarangwe, Lambert; Musengamana, Viateur; Vaneechoutte, Mario; Crucitti, Tania

    2015-01-01

    Bacterial vaginosis (BV), a condition defined by increased vaginal discharge without significant inflammation, is characterized by a change in the bacterial composition of the vagina. Lactobacillus spp., associated with a healthy vaginal microbiome, are outnumbered by BV-associated organisms. These bacteria could form a polymicrobial biofilm which allows them to persist in spite of antibiotic treatment. In this study, we examined the presence of Gardnerella vaginalis and Atopobium vaginae in vaginal biofilms using Peptide Nucleic Acid (PNA) probes targeting these bacteria. For this purpose, we developed three new PNA probes for A. vaginae. The most specific A. vaginae probe, AtoITM1, was selected and then used in an assay with two existing probes, Gard162 and BacUni-1, to evaluate multiplex FISH on clinical samples. Using quantitative polymerase chain reaction (qPCR) as the gold standard, we demonstrated a sensitivity of 66.7% (95% confidence interval: 54.5% - 77.1%) and a specificity of 89.4% (95% confidence interval: 76.1% - 96%) of the new AtoITM1 probe. FISH enabled us to show the presence of a polymicrobial biofilm in bacterial vaginosis, in which Atopobium vaginae is part of a Gardnerella vaginalis-dominated biofilm. We showed that the presence of this biofilm is associated with high bacterial loads of A. vaginae and G. vaginalis. PMID:26305575

  16. Clinical Holistic Medicine: Holistic Sexology and Acupressure Through the Vagina (Hippocratic Pelvic Massage

    Søren Ventegodt

    2006-01-01

    Full Text Available Many gynecological and sexological problems (like urine incontinence, chronic pelvic pains, vulvodynia, and lack of lust, excitement, and orgasm are resistant to standard medical treatment. In our work at the Research Clinic for Holistic Medicine in Copenhagen, we have found that vaginal acupressure, or Hippocratic pelvic massage, can help some of these problems. Technically, it is a very simple procedure as it corresponds to the explorative phase of the standard pelvic examination, supplemented with the patient's report on the feelings it provokes and the processing and integration of these feelings. Sometimes it can be very difficult to control the emotions released by the technique, i.e., regression to earlier traumas from childhood sexual abuse. This review discusses the theory behind vaginal acupressure, ethical aspects, and presentation of a case story. This procedure helped the patient to become present in her pelvis and to integrate old traumas with painful emotions. Holistic gynecology and sexology can help the patient to identify and let go of negative feelings, beliefs, and attitudes related to sex, gender, sexual organs, body, and soul at large. Shame, guilt, helplessness, fear, disgust, anxiety, anger, hatred, and other strong feelings are almost always an important part of a sexual or functional problem as these feelings are “held” by the tissue of the pelvis and sexual organs. Acupressure through the vagina/pelvic massage must be done with great care by an experienced physician, with a third person present, after obtaining consent and the necessary trust of the patient. It must be followed by conversational therapy and further holistic existential processing.

  17. Self-assessment of anatomy, sexual sensitivity, and function of the labia and vagina.

    Schober, Justine M; Alguacil, Nieves Martin; Cooper, R Scott; Pfaff, Donald W; Meyer-Bahlburg, Heino F L

    2015-04-01

    Patient perceptions of genital esthetics are motivating requests for plastic surgeries that could change sexual sensitivity. There is little information about the sensitivities of labial and introital sites. The aim of this study is to assess the relationship between sexual sensitivity and self-reported sizes of labial and introital sites. Sixty-two healthy, sexually active, adult women (mean age 37.9, range 21-60) with no history of genital or vaginal surgery gave written consent to participate in this study. A modified version of Self-Assessment of Genital Anatomy and Sexual Function (L-SAGASF-F) was used to assess labial and introital size. Site-specific sensation was rated on Likert scales of 1-5. Anatomical locations were compared for ratings. Of 62 responders, 84% (52) described their labia as "average-sized," 11% (7) described their labia minora and 13% (8) their labia majora as "large", and 3% (2) and 5% (3) as "small". Sexual pleasure ratings were "moderate" (median value: 3.0 for external genitalia and vaginal lumen) or "strong" (median value: 4.0 for the interior vagina). Significantly higher rankings related to the vaginal opening (P=0.007). Orgasm intensity for stimulation of the external genitalia progressively increased toward the vaginal opening, from 1.0 to 3.0 (P=0.001); vaginal ratings showed a similar progression, from 2.0 at the external luminal margin to 3.0 in the deep interior (P<0.0001). Orgasm effort scores were intermediate (median: 3.0), uniform throughout the external and internal areas (P=0.626). Ratings for labial and introital sensitivity, regardless of self-reported size, were very similar to those at other genital sites for sexual pleasure. Surgical excision of labial and introital structures could modify sexual sensation. PMID:25683213

  18. Seminal plasma protein profiles of ejaculates obtained by internal artificial vagina and electroejaculation in Brahman bulls.

    Rego, J P A; Moura, A A; Nouwens, A S; McGowan, M R; Boe-Hansen, G B

    2015-09-01

    The present study was conducted to investigate if differences exist in the seminal plasma protein profile from mature Brahman bulls using two methods of semen collection: internal artificial vagina (IAV) and electroejaculation (EEJ). Semen was collected four times from three bulls on the same day and parameters were assessed immediately post-collection. Seminal plasma proteins were evaluated by 2-D fluorescence difference gel electrophoresis and identified by mass spectrometry. Semen volume was greater (P < 0.05) for EEJ (4.6 ± 0.35 mL) than for IAV (1.86 ± 0.24 mL) but sperm concentration was greater in IAV (1505 ± 189 × 10(6) sperm/mL) than in EEJ samples (344 ± 87 × 10(6) sperm/mL). Sperm motility and the percentage of normal sperm were not different between treatments. Total concentration of seminal plasma proteins was greater for samples collected by IAV as compared to EEJ (19.3 ± 0.9 compared with 13.0 ± 1.8 mg/mL, P < 0.05; respectively). Based on 2-D gels, 22 spots had a greater volume (P < 0.05) in gels derived from IAV samples, corresponding to 21 proteins identified as transferrin, albumin, epididymal secretory glutathione peroxidase, among others. Thirty-three spots, corresponding to 26 proteins, had a greater volume (P < 0.05) in gels derived from EEJ samples. These proteins were identified as spermadhesin-1, Bovine Sperm Protin 1, 3 and 5 isoforms, angiogenin-1, alpha-1B-glycoprotein, clusterin, nucleobindin-1, cathepsins, spermadhesin Z13, annexins, among others. Thus, proteins in greater amounts in samples obtained by IAV and EEJ were mainly of epididymal origin and accessory sex glands, respectively. PMID:26282524

  19. 阴道平滑肌瘤25例临床分析%Clinical analysis of 25 cases of leiomyoma of the vagina

    钱建华; 郑斐; 石一复

    2001-01-01

    目的 探讨阴道平滑肌瘤的组织来源、临床特点和治疗方法。方法 回顾性分析1988年1月~1999年1月在我院住院手术并经病理检查证实的阴道平滑肌瘤25例。结果 阴道平滑肌瘤多为单发,生长缓慢,症状与肿瘤的大小及部位有关,可复发及恶性变。治疗方式为阴道平滑肌瘤剔除术。结论 阴道平滑肌瘤临床少见,一旦发现,均应及时手术治疗,以免肌瘤增大产生症状甚至恶性变。%Objective To study the histologic source, clinical features and treatment methods of leiomyoma of the vagina. Methods From January of 1988 to January of 1999, 25 patients with leiomyoma of the vagina were retrospectively analyzed. Results The clinical features of leiomyoma of the vagina were slow in growth and solitary in number. Leiomyoma of the vagina can be recurrence and sarcomatous change. The symptoms of leiomyoma of the vagina depended on the size and location of the leiomyoma. Treatment consisted of surgical excision by vagina. Conclusions Leiomyoma of the vagina is a rare condition. Whenever such a tumor is detected, it has to be removed immediately to prevent further growing and sarcomatous change in the future.

  20. Bladder cancer will grow anywhere: report of a urothelial carcinoma drop metastasis to the vagina and literature review.

    Uhlman, Matthew A; Bevill, Mark D; Goodheart, Michael J; Brown, James A; O'Donnell, Michael A

    2016-08-01

    Urothelial carcinoma is the 2nd most common cancer of the urinary tract and accounts for the majority of cases of bladder cancer. Metastases are not infrequently encountered, increasing with disease stage and are most commonly seen in the bones and lungs. Many other sites have been described including the omentum, liver, and ovaries. An extremely rare site of metastatic disease however is within the vagina. Here we present a case of a probable vaginal 'drop metastasis' from previously treated urothelial carcinoma in the ureter and bladder. PMID:27544563

  1. Dosimetric evaluation of a combination of brachytherapy applicators for uterine cervix cancer with involvement of the distal vagina; Avaliacao dosimetrica de uma combinacao de aplicadores para braquiterapia de tumores do colo uterino com acometimento da porcao distal da vagina

    Guimaraes, Roger Guilherme Rodrigues [Real e Benemerita Sociedade Portuguesa de Beneficencia, Sao Paulo, SP (Brazil). Servico de Radioterapia Estereotactica; Carvalho, Heloisa de Andrade; Stuart, Silvia Radwanski; Rubo, Rodrigo Augusto [Universidade de Sao Paulo (USP), SP (Brazil). Hospital das Clinicas. Servico de Radioterapia], e-mail: handrade@hcnet.usp.br; Seraide, Rodrigo Migotto [Centro de Oncologia Campinas, SP (Brazil)

    2009-07-15

    Objective: To evaluate an alternative brachytherapy technique for uterine cervix cancer involving the distal vagina, without increasing the risk of toxicity. Materials And Methods: Theoretical study comparing three different high-dose rate intracavitary brachytherapy applicators: intrauterine tandem and vaginal cylinder (TC); tandem/ring applicator combined with vaginal cylinder (TR+C); and a virtual applicator combining both the tandem/ring and vaginal cylinder in a single device (TRC). Prescribed doses were 7 Gy at point A, and 5 Gy on the surface or at a 5 mm depth of the vaginal mucosa. Doses delivered to the rectum, bladder and sigmoid colon were kept below the tolerance limits. Volumes covered by the isodoses, respectively, 50% (V50), 100% (V100), 150% (V150) and 200% (V200) were compared. Results: Both the combined TR+C and TRC presented a better dose distribution as compared with the TC applicator. The TR+C dose distribution was similar to the TRC dose, with V150 and V200 being about 50% higher for TR+C (within the cylinder). Conclusion: Combined TR+C in a two-time single application may represent an alternative therapy technique for patients affected by uterine cervix cancer involving the distal vagina. (author)

  2. Definitive radiotherapy for carcinoma of the vagina: outcome and prognostic factors

    Purpose: Primary carcinoma of the vagina is an uncommon tumor. Because of the long-standing interest in this disease at our institution a substantial number of patients with this disease has been accumulated, and this retrospective review was performed to define disease outcome, to delineate significant prognostic factors, and to provide treatment guidelines. Methods and Materials: This was a retrospective review of 301 patients with vaginal carcinoma (271 with squamous cell and 30 with adenocarcinoma) who received definitive radiotherapy between 1953 and 1991. Prognostic factors for outcome (local control, pelvic control, metastatic relapse, survival, and complications) were evaluated using univariate and multivariate techniques. Results: Patients disease was staged using the International Federation of Gynecology and Obstetrics (FIGO) system, and stages were distributed as follows: 0, 37 (12%); I, 65 (22%); II, 122 (40%); III, 60 (20%); and, IVA, 17 (6%). Treatment varied according to stage, with brachytherapy predominating for early disease but external beam playing a prominent role for more advanced disease. Patients with in situ disease received brachytherapy alone or transvaginal orthovoltage irradiation. For Stage I, brachytherapy alone was used in 25, external beam and brachytherapy in 38, and transvaginal alone in 2. For Stage II, brachytherapy alone was used in 20, external and brachytherapy in 66, and external irradiation alone in 36. For Stage III, external and brachytherapy was used in 15, and external alone in 45. Two patients with Stage IVA received brachytherapy alone, 10 received a combination of external and brachytherapy, and 6 received external irradiation alone. Total doses ranged from 10 to 154 Gy (mean 74.7 Gy, median 70.0 Gy), but only 18 (6%) received less than 55 Gy. At a median follow-up of 13 years, the 5-, 10-, 15-, 20-, and 25-year survival rates were 60%, 49%, 38%, 29%, and 23%, respectively. Beyond 5 years the survival rates relative

  3. Effect of seminal plasma on post-thaw quality and functionality of corriedale ram sperm obtained by electroejaculation and artificial vagina.

    Ledesma, A; Manes, J; Ríos, G; Aller, J; Cesari, A; Alberio, R; Hozbor, F

    2015-06-01

    We have already shown that seminal collection method affects seminal plasma composition and sperm quality in Corriedale rams. In this study, we evaluated the effect of seminal plasma collected by electroejaculation or artificial vagina on sperm resistance to cryodamage. Seminal plasma of five rams of the Corriedale breed collected by artificial vagina or electroejaculation was added before freezing to sperm cells collected by the two methods, and post-thaw quality parameters were evaluated. We found that seminal plasma has no effect on sperm resistance to cryodamage. However, we observed significantly higher percentages of sperm with intact and functional plasma membrane, intact acrosome and greater fertilizing potential after thawing in samples obtained by electroejaculation. This study demonstrates that sperm collected by electroejaculation are more resistant to damage caused by cryopreservation than those collected by artificial vagina. PMID:25684063

  4. Ultrastructural study of the neovagina following the utilization of human amniotic membrane for treatment of congenital absence of the vagina

    L.F. Bleggi-Torres

    1997-07-01

    Full Text Available We present an ultrastructural study of the utilization of human amniotic membrane in the treatment of congenital absence of the vagina in 10 patients. All patients were surgically treated with application of an amniotic membrane graft using the modified McIndoe and Bannister technique. Sixty days after surgery, samples of the vaginal neo-epithelium were collected for transmission electron microscopy analysis. The ultrastructural findings consisted of a lining of mature squamous epithelium indicating the occurrence of metaplasia of the amniotic epithelium into the vaginal epithelium. The cells were arranged in layers as in the normal vaginal epithelium, i.e., superficial, intermediate and deep layers. There were desmosomes and cytoplasmic intermediate cytokeratin filaments, as well as some remnant features of the previous amniotic epithelium. These findings suggest that human amniotic membrane is able to complete metaplasia into squamous cells but the mechanism of this cellular transformation is unknown

  5. Analysis of study rezults of biopsies of the vagina mucous membrane in women with recurrent genital prolapse

    Banakhevich R.M.

    2014-06-01

    Full Text Available The study involved 53 women with recurrent genital prolapse. The average age of the women studied was 62,8±9,8 years, age of women of the control group was 57,2±6,3 years (p>0,05. Features of expression of estrogen and progesterone receptors levels, markers of cell proliferation and collagen in the biopsy of the vagina mucous membrane were estimated. In the vaginal mucosa of patients with recurrent prolapse expression of Ki-67 markers of proliferative activity was not established. According to the study general lowering of estrogen receptors by 76,2% in patients with recurrent genital prolapse was established, whereas in patients of the control group level of estrogen receptors in the unchanged epithelium and stroma was positive in 100% of cases. In patients with recurrent genital prolapse the decrease of expression of progesterone receptors by 83,4% was identified.

  6. Ultrastructural features of vagina at different phases of the oestrous cycle in the female African giant rat (Cricetomys gambianus Waterhouse).

    Akinloye, Adebayo K; Oke, Bankole O

    2014-06-01

    The ultrastructures of the vagina at various stages of the oestrous cycle in female African giant rats (Cricetomys gambianus Waterhouse) were described in the present study. At mid-proestrus, late proestrus (LP)/early estrus (EE) and mid-estrus (ME) as well as late metestrus (LM)/early diestrus (ED) and mid-diestrus (MD), complex interface of epithelium and lamina propria were observed. Cells of the stratum basale formed finger-like extensions into the underlying lamina propria and tips of the extensions displayed hemidesmosome while basal lamina followed the contour of the extensions. At mid-metestrus (MM) and late diestrus/early proestrus, well developed, relatively straight basal lamina interfaced between the stratum basale and the lamina propria without finger-like projections. Polygonal cells with indented nuclei and, cytoplasm containing ribosomes, polysomes, intermediate filaments, and mitochondria were observed in stratum spinosum at all the phases of the oestrus cycle. At MM, LM/ED, and MD, the stratum spinosum had numerous desmosomes with tonofilaments, large microvilli that intermingled at the intercellular spaces and evidence of trapped/migrating neutrophils and lymphocytes. The superficial layer displayed short microvilli at mid-proestrus, cornification at LP/EE and desquamation at ME while it showed condensation of intermediate filaments; projections of large microvilli into the luminal surface at MM, and embeddement of neutrophils at LM/ED as well as MD. This study looked into the reproductive biology of female African giant rats to produce baseline information on its reproductive organs and represented the first comprehensive description of the vagina at the ultrastructural level during oestrous cycle. PMID:24737725

  7. Nonoxynol-9 berberine plural gel has little effect on expression of SLPI, SP-D and lactoferrin in mice’s vagina

    Huang Guangying

    2013-01-01

    Full Text Available Background: The most frequently used spermicide Nonoxynol-9 (N-9 in the clinic alters the vaginal flora, which will result in an increased risk of opportunistic infection. So development of a novel spermicidal and microbicidal drug appears to be inevitable. Vaginal local immune is an important part of vaginal flora. Secretory leukocyte protease inhibitor (SLPI, surfactant proteins D (SP-D, and lactoferrin (LF are anti-microbial molecules with important roles in immune system of female vaginas. Objective: To observe effect of a vaginal spermicide nonoxynol-9 (N-9 berberine plural gel on the expression of SLPI SP-D and LF in mice’s vaginas. Materials and Methods: Female BABL/C mice were randomly divided into following 5 groups: normal control group, blank gel group, berberine gel group, 12% N-9 gel group and N-9 berberine plural gel group. Estradiol benzoate at physiological dose was done by hypodermic injection to every group’s mice. After 72h, drug gels were separately injected into the mice’s vaginas, while immunohistochemistry and Western blot were taken to detect the expression of the 3 indexes in mice’s vaginas respectively after 24h and 72h of gel injection. Results: The differences in the three indexes between normal control group and blank gel group were not significant statistically (p>0.05. The expression of the three indexes in 12% N-9 gel group was decreased compared to that in blank gel group (p0.05. Also, the three index's level of 24h and 72h in sub observation groups after treatment were without statistical significance (p>0.05. Conclusion: Application of N-9 berberine plural gel had little impact on antimicrobial peptides in normal mice’s vaginas.

  8. Rapidly disintegrating vagina retentive cream suppositories of progesterone: development, patient satisfaction and in vitro/in vivo studies.

    Bendas, Ehab Rasmy; Basalious, Emad B

    2016-05-01

    Our objective was to develop novel vagina retentive cream suppositories (VRCS) of progesterone having rapid disintegration and good vaginal retention. VRCS of progesterone were prepared using oil in water (o/w) emulsion of mineral oil or theobroma oil in hard fat and compared with conventional vaginal suppositories (CVS) prepared by hard fat. VRCS formulations were tested for content uniformity, disintegration, melting range, in vitro release and stability studies. The most stable formulation (VRCS I) was subjected to scaling-up manufacturing and patients' satisfaction test. The rapid disintegration, good retentive properties are applicable through the inclusion of emulsified theobroma oil rather than hydrophilic surfactant into the hard fat bases. The release profile of progesterone from VRCS I showed a biphasic pattern due to the formation of progesterone reservoir in the emulsified theobroma oil. All volunteers involved in patients' satisfaction test showed high satisfactory response to the tested formulation (VRCS). The in vivo pharmacokinetic study suggests that VRCS of progesterone provided higher rate and extent of absorption compared to hard fat based suppositories. Our results proposed that emulsified theobroma oil could be promising to solve the problems of poor patients' satisfaction and variability of drug absorption associated with hard fat suppositories. PMID:25567033

  9. 非培养法检测阴道微生态的进展%Research Progress of Detecting Vagina Microecology by Cultivation-Independent Methods

    陈晴

    2012-01-01

    女性阴道内寄生着多种微生物,鉴定阴道中存在的微生物有助于了解其在健康和疾病时的作用,但是许多微生物难以通过培养将其分离鉴定.近年来,一系列分子生物学的方法,如基于16S rRNA基因聚合酶链反应扩增法等用于研究阴道微生态并取得了较大的进展.利用分子生物学的非培养法检测女性阴道微生物发现,不论在健康女性还是细菌性阴道病(BV)患者中惰性乳杆菌是普遍存在的乳杆菌;还发现许多新的厌氧菌与BV高度相关,如阴道阿托波菌、阴道加德纳菌、BVAB1等.%The human vagina hosts many microbes. Identifying all kinds of microbes in vagina will help to better understand their roles in heath and disease. However,many microbes are difficult to be identified by cultivation-dependent methods. In recent years, a series of molecular approaches, such as PCR amplification of 16S rRNA gene,are used to study the vagina microecology and have made considerable progress. The use of molecular, cultivation-independent methods have revealed :lactobacillus inert is the ubiquitous nature in women with or without bacterial vaginosis( BV ); some novel anaerobes are strongly associated with BV, such as Atopobium vaginae, Gardnerella vaginalis, BVAB1 and so on.

  10. 25例先天性无阴道的手术治疗%Surgical treatment of 25 patients with congenital absence of vagina

    游艳琴; 宋磊; 李立安

    2012-01-01

    Objective To study the curative effect of surgical treatment on congenital absence of vagina. Methods Clinical data about 25 patients with congenital absence of vagina admitted to our hospital from 2006 to 2011 were retrospectively analyzed. Of these patients, 20 underwent vaginoplasty with acellulardermal repairing patch, 3 underwent vaginoplasty with peritoneum, and 2 underwent vaginoplasty with amniotic membrane. Results The vagina mucosa was formed in 19 patients 8 weeks after vaginoplasty with acellulardermal repairing patch and in 1 patient after vaginoplasty with peritoneum. The satisfactory rate of the patients for sexual life was 90%. Conclusion The time of vagina mucosa formation is relative short after vaginoplasty with acellulardermal repairing patch. The satisfactory rate of vaginoplasty with acellulardermal repairing patch is high, and the procedure deserves to be recommended.%目的 探讨先天性无阴道患者的手术疗效.方法 回顾性分析2006 年1 月-2011 年6 月我科就诊的25 例先天性无阴道患者的临床资料,20 例行脱细胞异体真皮补片人工阴道成形术,3 例行腹会阴联合腹膜代阴道成形术,2 例行羊膜代阴道成形术.结果 19 例脱细胞异体真皮补片人工阴道成形术和1 例腹膜阴道成形术者在术后8 周人工阴道完全黏膜化,性生活满意率为90%.结论 脱细胞异体真皮补片阴道成形术后阴道黏膜化时间短,满意率高,是一种值得推广的术式.

  11. Persistence of Lactobacillus fermentum RC-14 and Lactobacillus rhamnosus GR-1 but Not L. rhamnosus GG in the Human Vagina as Demonstrated by Randomly Amplified Polymorphic DNA

    Gardiner, Gillian E.; Heinemann, Christine; Bruce, Andrew W.; Beuerman, Dee; Reid, Gregor

    2002-01-01

    Lactobacillus rhamnosus GR-1 and L. fermentum RC-14 are well-characterized probiotic strains with efficacy in the prevention and treatment of urogenital infections in women. The aim of the present study was to apply a molecular biology-based methodology for the detection of these strains and L. rhamnosus GG (a commercially available intestinal probiotic) in the human vagina in order to assess probiotic persistence at this site. Ten healthy women inserted vaginally a capsule containing either ...

  12. Gene polymorphisms of Toll-like and related recognition receptors in relation to the vaginal carriage of Gardnerella vaginalis and Atopobium vaginae.

    Verstraelen, Hans; Verhelst, Rita; Nuytinck, Lieve; Roelens, Kristien; De Meester, Els; De Vos, Daniel; Van Thielen, Martine; Rossau, Rudi; Delva, Wim; De Backer, Ellen; Vaneechoutte, Mario; Temmerman, Marleen

    2009-01-01

    Host genetic factors have previously been found to act as determinants of differential susceptibility to major infectious diseases. It is less clear whether such polymorphisms may also impose on pathogen recognition in mucosal overgrowth conditions such as bacterial vaginosis, an anaerobic overgrowth condition characterised by the presence of a vaginal biofilm consisting of the Gram-positive anaerobes Gardnerella vaginalis and Atopobium vaginae. We selected 34 single nucleotide polymorphisms pertaining to 9 genes involved with Toll-like receptor-mediated pathogen recognition and/or regulation (LBP, CD14, TLR1, TLR2, TLR4, TLR6, MD2, CARD15 and SIGIRR) and assessed in a nested case-control study their putative association with bacterial vaginosis, as diagnosed by Gram staining, and with the vaginal carriage of A. vaginae and G. vaginalis, as determined by species-specific PCR, among 144 pregnant women. Carriage of G. vaginalis during early pregnancy was associated with the -1155A>G substitution in the promoter region of the MD2 gene (p=0.041). The presence of A. vaginae during the first half of the pregnancy was significantly associated with the CD14 intron 2 1342G>T (p=0.039), the TLR1 exon 4 743A>G (p=0.038), and the CARD15 exon 4 14772A>T (p=0.012) polymorphisms, and marginally significantly associated with the LBP exon13 26842C>T (p=0.056), the CD14 promoter -260C>T (p=0.052), and the TLR1 promoter -7202A>G (p=0.062) polymorphisms. However, no association between gene polymorphisms and bacterial vaginosis as such could be documented. Our data suggest that some degree of genetic susceptibility involving pathogen recognition may occur with the key bacterial vaginosis organism, A. vaginae. PMID:19200604

  13. Characterisation of the bacterial microbiota of the vagina of dairy cows and isolation of pediocin-producing Pediococcus acidilactici

    Wang Yvonne

    2013-01-01

    Full Text Available Abstract Background Uterine infections in dairy cows lower profitability of dairy operations. Infections of the reproductive tract are related to the overgrowth of pathogenic bacteria during the first three weeks after parturition. However, alterations in the vaginal microbiota composition in the first weeks after parturition remain poorly documented. Results In this study, bacteria isolated from the vagina of healthy pregnant, and infected postpartum cows were characterised by random amplification of polymorphic DNA (RAPD analysis and partial 16S ribosomal RNA (rDNA gene sequencing. Populations of bacilli and lactic acid bacteria of the genera Enterococcus, Lactobacillus, and Pediococcus were present in both healthy and infected cows. Infected cows had a significant increase in the vaginal enteric bacteria population which consisted mainly of Escherichia coli. Three E. coli isolates harboured the gene coding for Shiga-like-toxin (SLT I or II. Several isolates of the Pediococcus acidilactici were found to produce the bacteriocin pediocin AcH/PA-1. Quantitative PCR analyses of vaginal mucus samples collected from ten metritic cows before and after parturition confirmed the presence of the Lactobacillus group (Lactobacillus spp., Pediococcus spp., Leuconostoc spp., and Weissella spp.; Enterobacteriaceae, E. coli, and bacilli. The presence of the pediocin AcH/PA-1 structural gene and SLT genes were also confirmed with qPCR. Conclusions In conclusion, overgrowth of pathogenic bacteria, particularly E. coli, after parturition likely contributes to the development of metritis. Our microbiota analysis extends the information related to the composition of commensal bacteria in the bovine female reproductive tract and may facilitate the development of novel intervention strategies for prevention of uterine infections in dairy cows.

  14. Il Linguaggio della Vagina

    Marco Menicocci

    2011-01-01

    La cultura delle masse è oggi una cultura prevalentemente visuale. Tra i segni visuali da tempo in crescita è quello, caratteristico, della depilazione pubica femminile. Originata all'interno della cultura porno come segno di passività, questa pratica si è incontrata con i simboli della pulizia, dell'igiene, del rispetto, trasformando così il proprio significato in quello di autonomia e libertà. Così le donne possono depilarsi per scopi erotici minimizzando però la valenza sessuale del gesto ...

  15. Il Linguaggio della Vagina

    Marco Menicocci

    2011-12-01

    Full Text Available La cultura delle masse è oggi una cultura prevalentemente visuale. Tra i segni visuali da tempo in crescita è quello, caratteristico, della depilazione pubica femminile. Originata all'interno della cultura porno come segno di passività, questa pratica si è incontrata con i simboli della pulizia, dell'igiene, del rispetto, trasformando così il proprio significato in quello di autonomia e libertà. Così le donne possono depilarsi per scopi erotici minimizzando però la valenza sessuale del gesto tramite la tendenza alla super-igiene.

  16. Cloning of 16S rRNA genes amplified from normal and disturbed vaginal microflora suggests a strong association between Atopobium vaginae, Gardnerella vaginalis and bacterial vaginosis

    De Ganck Catharine

    2004-04-01

    Full Text Available Abstract Background The pathogenesis of bacterial vaginosis remains largely elusive, although some microorganisms, including Gardnerella vaginalis, are suspected of playing a role in the etiology of this disorder. Recently culture-independent analysis of microbial ecosystems has proven its efficacy in characterizing the diversity of bacterial populations. Here, we report on the results obtained by combining culture and PCR-based methods to characterize the normal and disturbed vaginal microflora. Results A total of 150 vaginal swab samples from healthy women (115 pregnant and 35 non-pregnant were categorized on the basis of Gram stain of direct smear as grade I (n = 112, grade II (n = 26, grade III (n = 9 or grade IV (n = 3. The composition of the vaginal microbial community of eight of these vaginal swabs (three grade I, two grade II and three grade III, all from non-pregnant women, were studied by culture and by cloning of the 16S rRNA genes obtained after direct amplification. Forty-six cultured isolates were identified by tDNA-PCR, 854 cloned 16S rRNA gene fragments were analysed of which 156 by sequencing, yielding a total of 38 species, including 9 presumptively novel species with at least five species that have not been isolated previously from vaginal samples. Interestingly, cloning revealed that Atopobium vaginae was abundant in four out of the five non-grade I specimens. Finally, species specific PCR for A. vaginae and Gardnerella vaginalis pointed to a statistically significant co-occurrence of both species in the bacterial vaginosis samples. Conclusions Although historically the literature regarding bacterial vaginosis has largely focused on G. vaginalis in particular, several findings of this study – like the abundance of A. vaginae in disturbed vaginal microflora and the presence of several novel species – indicate that much is to be learned about the composition of the vaginal microflora and its relation to the etiology of BV.

  17. An Investigation About the Effects of Insemination Depth, Cervico-Vaginal Mucus Production and Reflux of Semen in the Vagina After Insemination in Sheep

    Koşum, Nedim

    2000-01-01

    The possible influence of factors such as depth of insemination, cervico-vaginal mucus production and reflux of semen in the vagina after insemination in German merinolandrace were considered. Fresh diluted semen was inseminated intracervically. The results obtained for non-return-rate, lambing rate and fecundity are 49.01%, 39.75% and 64.55% respectively. The year had a significant effect (p ² 0.05) on non-return-rate and lambing rate but not on fecundity.The other parameters considered d...

  18. 婴幼儿阴道内胚窦瘤的CT和MRI诊断%CT and MRI diagnosis of endodermal sinus tumor of vagina in infants

    胡悦林; 刘鸿圣; 罗源利; 周宁; 田金生; 鹿连伟

    2013-01-01

      目的探讨婴幼儿阴道内胚窦瘤的CT和MRI表现特点。方法回顾性分析8例经病理证实的婴幼儿阴道内胚窦瘤的CT及MRI表现,分析总结其影像学特点。结果阴道内胚窦瘤瘤体较大,多呈类圆形,CT平扫密度欠均匀,均可见坏死囊变区域。MRI检查瘤体在T1WI序列上呈等低混杂信号,在T2WI序列上以稍高信号为主,信号混杂不均。CT及MRI增强扫描均呈明显不均匀强化,以病灶周边强化最为显著。结论阴道内胚窦瘤的CT和MRl表现具有一定特征性,结合血清AFP显著升高,可以明确诊断。MRI在显示病灶向周围浸润程度、判断疗效及肿瘤复发方面优于CT。%  Objective To assess the CT and MRI features of endodermal sinus tumors of vagina in infants.Methods The CT and MRI of pathologically confirmed endodermal sinus tumors of vagina in eight infants were analyzed retrospectively.Results Endodermal sinus tumor of vagina showed a large soft tissue mass similar-circular,and the density was inhomogeneous All cases are Endodermal sinus tumor of vagina appeared as a large round soft tissue mass with heterogeneous density,variable necrosis and cystic degeneration on unenhanced CT. The tumor had heterogeneous low to intermediate T1 and slightly high T2 signal intensities. Heterogeneous enhancement especially peripherally was noted on both CT and MRI.Conclusions The CT and MRI features of heterogeneously enhancing vaginal mass with necrosis and cystic degeneration in the setting of elevatedα-fetoprotein level suggest diagnosis of endodermal sinus tumor. MRI is superior to CT in showing surrounding tumor infiltration and tumor recurrence.

  19. Histopathologic Changes in the Uterus, Cervix and Vagina of Immature CD-1 Mice Exposed to Low Doses of Perfluorooctanoic Acid (PFOA) in a Uterotrophic Assay

    Dixon, Darlene; Reed, Casey E.; Moore, Alicia B.; Gibbs-Flournoy, Eugene A; Hines, Erin P.; Wallace, Elizabeth A.; Stanko, Jason P.; Lu, Yi; Jefferson, Wendy N.; Newbold, Retha R.; Fenton, Suzanne E.

    2011-01-01

    The estrogenic and antiestrogenic potential of perfluorooctanoic acid (PFOA) was assessed using an immature mouse uterotrophic assay and by histologic evaluation of the uterus, cervix and vagina following treatment. Female offspring of CD-1 dams were weaned at 18 days old and assigned to groups of equal weight, and received 0, 0.01, 0.1, or 1 mg PFOA/kg BW/d by gavage with or without 17-β estradiol (E2, 500 μg/kg/d) from PND18-20 (n=8/treatment/block). At 24 hr after the third dose (PND 21), ...

  20. La vagina dentada: una interpretación de la Estela 25 de Izapa y las guacamayas del juego de pelota de Copán The dented vagina: an interpretation for Stela 25 of Izapa and ballcourt macaws of Copan

    Oswaldo Chinchilla Mazariegos

    2010-01-01

    Full Text Available Las aves representadas en la Estela 25 de Izapa y el juego de pelota de Copán forman el punto de partida para un examen del tema mitológico de la vagina dentada en Mesoamérica, y sus expresiones en el arte y la narrativa. Un amplio conjunto de narraciones mitológicas recopiladas en México y Guatemala sirve como base para un examen de la historia de Siete Guacamayo en el Popol Vuh, la cual se interpreta como una variante de un mito ampliamente difundido, relacionado con el origen del Sol y la Luna. La identificación de asuntos comunes, entre ellos el de la vagina dentada, refuerza la relación entre el mito del Popol Vuh y las representaciones de Izapa y Copán. A la vez, revela detalles poco conocidos sobre el simbolismo sexual presente en los mitos cosmogónicos mesoamericanos.The birds represented at Stela 25 of Izapa and Copan ball court are the starting point for the analysis of the mythological topic focused on the vagina dentata in Ancient Mesoamerica, as well as their expressions on art and narrative. A large body of mythological narratives is used as a basis for the examination of the "Siete Guacamayo" story included in the Popol Vuh, which is interpreted as part of a widely extended myth related with the creation of the Sun and the Moon. The identification of common issues, as the vagina dentata topic, strengthens the links between the Popol Vuh myth and the Izapa and Copan representations. It also reveals less known details on the sexual symbolism included in the Mesoamerican cosmogonic myths.

  1. Normal tissue tolerance to external beam radiation therapy: The vagina; Dose de tolerance a l'irradiation des tissus sains: le vagin Normal

    Magne, N. [Unite de curietherapie, departement de radiotherapie, institut de cancerologie de la Loire, 42 - Saint-Priest-en-Jarez (France); Chargari, C. [Service d' oncologie radiotherapie, hopital d' instruction des armees du Val-de-Grace, 75 - Paris (France); Pointreau, Y. [Clinique d' oncologie radiotherapie, centre Henry-S.-Kaplan, hopital de Bretonneau, CHU de Tours, 37 - Tours (France); Haie-Meder, C. [Service de curietherapie, departement de radiotherapie, institut Gustave-Roussy, 94 - Villejuif (France)

    2010-07-15

    The vagina is a virtual cavity involved in sexual reproduction field. Due to its anatomical location, it may be exposed in whole or in part to ionizing radiation in external radiotherapy and/or brachytherapy of the pelvic region. This review aims to describe the vaginal acute and late side effects due to radiation, probably inadequately reported in the literature. Medline and PubMed literature searches were performed using the keywords -vaginal - radiotherapy - toxicity. The acute and late functional changes after external beam radiation consist mainly of drought. Their incidences are poorly described in the literature and the delivered doses even less. Recommendations are non-existent as the normal tissue complication probability (NTCP). Brachytherapy delivers high and heterogeneous doses, making it difficult to estimate the dose. The concomitant administration of chemotherapy appears to be a factor increasing the risk of toxicity. Modern techniques of conformal radiotherapy with modulated intensity appear to have little impact on this body. Only a maximum dose on each third of the vagina appears to be currently proposed to avoid the risk of side effects. (authors)

  2. Conceptual knowledge of vesico-vagina fistula among parents, teachers and counsellors of senior secondary students in Warri South local government area of Delta State, Nigeria

    Imoukhede M.O

    2015-04-01

    Full Text Available Background: VVF is leakages of urine and faeces through the vagina. It is rampant in the North and the Eastern parts of Nigeria due to the forced marriage of girls at about the age of eleven. This may be attributed to their small pelvises which have resulted in harmful reproductive health practice. The disability and suffering from obstetric fistula remains a neglected issue in global health. Aim: This study seeks to explore the conceptual knowledge of vesico-vagina fistula (VVF among parents, teachers and counselors of senior secondary school students in Warri South local government area of Delta state. Methods: A survey design was used. Random sampling method was used to select a total number of six hundred respondents including parents, teachers and counselors that participated in the study, but only five hundred and eleven questionnaires were retrieved. The questionnaire was divided into two sections containing information on demography and selected variables for the study. Data was analyzed using descriptive statistics of Anova and t-tests. Result: the study revealed that there is no significant difference in the conceptual knowledge of VVF among parents, teachers and counselors of senior secondary school students either by educational status or location. Conclusion: It can be concluded that parents, teachers and counselors of senior secondary school have very little knowledge about VVF. There is need for educational programmes on VVF to enlighten them about VVF and the danger it poses.

  3. The Clinical Application of Micro-ecosystem in Vagina and Mixed Infection%阴道微生态评价系统的临床应用与混合感染

    王梅(综述); 岳惠芬(审校)

    2015-01-01

    The microbe community of the vagina has formed a coordinated equivalent balance with the host cell and the environment.This kind of micro-ecosystem balance of the vagina is necessary for maintai-ning the well-being of the organism.Many reproductive tract infection diseases were usually found in clinical entity because of the imbalance of the micro-ecology of the vagina.The evaluating system of the micro-eco-system of the vagina could quickly diagnose the common clinical vaginitis .To fully evaluate the vaginosis and the situation of the micro-ecosystem of the vagina before and after the treatment plays an important role in treating the complicated infection of the vagina and decreasing the recurrence .%阴道内的微生物群落与宿主、环境构成了动态协调的平衡关系,这种阴道的微生态平衡对维持机体的健康是必要的。许多临床上常见的生殖道感染性疾病均存在的明显的阴道微生态系统失衡,阴道微生态评价体系可以快速诊断临床常见的阴道炎症,全面评价阴道感染及治疗前后的阴道微生态状况,对阴道混合感染的治疗及降低复发率等起着重要的作用。

  4. Total cystectomy and subsequent urinary diversion to the prepuce or vagina in dogs with transitional cell carcinoma of the trigone area: a report of 10 cases (2005-2011).

    Saeki, Kohei; Fujita, Atsushi; Fujita, Naoki; Nakagawa, Takayuki; Nishimura, Ryohei

    2015-01-01

    The cases of 10 dogs with transitional cell carcinoma of the urinary bladder that underwent total cystectomy were retrospectively reviewed to evaluate the feasibility and outcome of total cystectomy and ureteral transplantation to the prepuce or vagina. Dehiscence of ureterostomy (n = 2), pyelonephritis (n = 3), oliguria (n = 2), azotemia (n = 1), and ureteral obstruction (n = 1) were observed complications. The estimated median survival time was 385 days. This study demonstrates the feasibility of total cystectomy and subsequent urinary diversion to the prepuce or vagina in dogs. Compared to previous ureterocolonic anastomosis, this technique is associated with fewer gastrointestinal and neurologic complications. PMID:25565719

  5. The use of peritoneum for laparoscopic vaginoplasty in patients with congenital absence of vagina%腹腔镜下腹膜代阴道治疗先天性无阴道

    王明波; 刘穗; 刘喻; 余幼辉

    2010-01-01

    目的 探讨腹腔镜下腹膜代阴道成形术的效果.方法 2003年10月至2009年1月共行腹腔镜下腹膜代阴道成形术9例,通过腹腔镜探查盆腔,游离盆腔腹膜,分离人工阴道腔穴,将游离盆腔腹膜自人工腔穴牵出,缝合形成人工阴道.结果 手术时问120~170 min,术中出血50~200 ml,术后第2天肛门排气,人工阴道深度10~12 cm.随访时间3年,人工阴道黏膜红润、光滑、弹性好,功能和形态达到生理要求,已婚者述性生活满意.结论 腹腔镜下腹膜代阴道成形术创伤小,术后恢复快,不破坏机体完整性,腹膜形成的阴道壁光滑,与正常阴道黏膜相似,符合生理状态,是治疗先天性无阴道较理想的手术方式.%Objective To study the effect of the use of peritoneum tor laparoscopic vaginoplasty in patients with congenital absence of vagina.Methods 9 patients with congenital absence of vagina were perfomed peritoneum for laparoscopic vaginoplasty from Oct ,2003 to Jan ,2009.Explore the pelvic by laparoscopic vaginoplasty,free the pelvic peritoneum,detach artificial vagina,pull the pelvic peritoneum from the artificial vagina,suture to form a vagina.Results The operation time was 120 ~ 170 minutes.Blood loss of operation was 50 ~200 ml.All patients had gas discharged 2 days after operation.Depth pf vagina made were 10 ~ 20 cm.3 years after operation,the vagina made all have a smoothy and tendy mucous membrane that their function or shape reached physiological goal Patients or their spouses were satisfied to their sex activity.Conclusion Use of peritoneum for laparoscopic vaginoplasty in patients with congenital absence of vagina has the advantages of short operation time,rapid recovery and no impact of physiological organ.Vagina membrane made by peritonem were smoothy and alike to normal vagina membrane.The use of peritoneum for laparoscopic vaginoplasty is an good operation way in patients with congenital absence of vagina.

  6. Effect of Bacterial Vaginitis on the Immune Environment of Vagina%细菌性阴道炎对阴道免疫环境的影响

    姚锋

    2015-01-01

    目的:探讨细菌性阴道炎对阴道内免疫环境的影响。方法2015年1—7月整群收集该院诊治的80例细菌性阴道炎患者和80例正常妇女阴道灌洗液和白带,ELISA检测阴道灌洗液中IL-1β,IL-6, IL-8及HBD-2。白带涂片革兰氏染色镜检阴道杆菌和其他杂菌的数目。结果细菌性阴道炎组较正常妇女组阴道内IL-1β水平升高(P<0.001), HBD-2水平降低(P<0.001),IL-6,IL-8差异无统计学意义(P=0.631,P=0.764)。细菌性阴道炎组较正常妇女组阴道内杂菌数量增多(P<0.001),阴道杆菌数量减少(P<0.001)。结论阴道杆菌对阴道内环境有免疫调节作用,细菌性阴道炎杂菌生长会破坏阴道内免疫环境。%Objective To study the effect of bacterial vaginitis on the immune environment of vagina. Methods From Jan-uary 2015 to July 2015 ,vaginal lavage fluid and leucorrhea of 80 cases of bacterial vaginitis patients and 80 cases of nor-mal women were collected , IL-1β,IL-6, IL-8 and HBD-2 in vaginal lavage fluid were detected by ELISA, the number of vagina bacillus and other miscellaneous bacteria was examined by leucorrhea smear gram staining microscopic. Results Compared with the normal women group, IL-1βlevel of vaginal internal in the bacterial vaginitis group increased (P<0.001) and HBD-2 decreased (P<0.001),the difference of IL-6 and IL-8 was not statistically significant (P=0.631,P=0.764). Compared with the normal women group, the number of miscellaneous bacteria in the bacterial vaginitis group increased (P<0.001)but the number of vagina bacillus decreased (P<0.001). Conclusion Vagina bacillus has an immune and adjustment effect on vaginal internal environment and the growth of bacterial vaginitis bacteria can destroy vaginal internal immune environment.

  7. [Cytological and bacteriological examinations of the cervix and vagina. A review of the results obtained in a laboratory for analyses in Guadeloupe (author's transl)].

    Millan, J; Crenn, O; Lidome, E

    1981-01-01

    The authors give the results of their cytological and bacteriological examinations of the cervix and vagina carried out routinely in a laboratory. They emphasize, in detailing their method of working, the criteria that they feel must be adopted in an attempt to code the qualitative appraisal of direct examination and the result of studying the cultures. The first part of the paper deals with an overall survey of the 4,573 examinations which were carried out over a period of 8 years. The second part is concerned with a more detailed analysis of the 883 samples which were divided into 4 categories: pregnant women, those having oral contraception, those with an intra-uterine device, and others. There are several variations revealed between these 4 categories as far as the white cell count, the bacterial flora and even pathogenic organisms are concerned. PMID:7334191

  8. The effect of copaiba balsam on Walker 256 carcinoma inoculated into the vagina and uterine cervix of female rats Efeito do óleo de copaíba no tumor de Walker 256 inoculado em vagina e colo de útero de ratas fêmeas

    Nara Macedo Botelho Brito; Marcus Vinicius Henriques Brito; Rita de Kássia Vidigal Carvalho; Lia Tavares de Moura Brasil Matos; Rodolfo Costa Lobato; Suelen Costa Correa; Rosângela Baía Brito

    2010-01-01

    PURPOSE: To verify the copaiba balsam (Copaifera officinalis) effect on Walker 256 carcinoma inoculated into vagina and uterine cervix of rats. METHODS: Eighteen female Wistar rats weighing between 180-250g were used, distributed into 2 groups (GCop, GC). On the 1st day of the experiment, 0.3 ml of Walker 256 carcinoma (2x10(6) concentration) was inoculated in both groups; on the 3rd day of the experiment, it was given 4.8 ml/kg of distilled water to the GC group, and 4.8 ml/kg of copaiba bal...

  9. Curative observation of disposable bacteriostatic absorber for vagina in the treatment of gestational candida vulva va-gina disease%唯阴康治疗妊娠期念珠菌性外阴阴道病效果观察

    杨春; 宋晓蓉

    2014-01-01

    目的:观察唯阴康治疗妊娠期念珠菌性外阴阴道病的临床疗效及安全性。方法选取门诊2012年5月-2013年11月诊治妊娠期念珠菌性外阴阴道病患者95例,随机分为观察组(唯阴康治疗)50例和对照组(碳酸氢钠冲洗)45例,治疗10d 后比较治疗效果并观察不良反应。结果观察组总有效率为86.0%高于对照组的62.2%,差异有统计学意义(P <0.05)。2组患者治疗期间均未出现明显不良反应。结论唯阴康治疗妊娠期念珠菌性外阴阴道病方便、安全、有效,值得临床推广。%Objective To explore the clinical effect and safety of disposable bacteriostatic absorber for vagina(Weiy-inkang)in the treatment of gestational candida vulva vagina disease. Methods During May 2012 to November 2013,125 ca-ses of patients with gestational candida vulva vagina disease cured by outpatient was selected as the research objects,which were randomly divide into observation group(Weiyinkang treatment)including 50 cases,and control group(sodium bicarbon-ate flush)including 45 cases according to the random number table,and the treatment effect and adverse reaction of which were compared after ten days' cure. Results The total effective rate of observation group was 86. 0% ,which was higher than 62. 2% of the control group,and the difference was statistical significance(P < 0. 05). Neither of 2 groups had obvious ad-verse reaction. Conclusion The treatment of Weiyinkang on gestational candida vulva vagina disease is convenient,safe and effective,which is worthy of clinical promotion.

  10. Three-dimensional(3D) Pelvic Floor Ultrasound:Transversal Imaging of Nulliparous Vagina at Different Level%未产妇阴道不同水平横断面的三维盆底超声观察

    李勤; 胡兵; 应涛

    2009-01-01

    Objective To search for an effective imaging method for the morphological observation of female pelvic support by studying 3D ultrasound image features of nulliparous vagina and perivaginal structures at different level.Methods Fifty nulliparas were examined by 3D pelvic floor ultrasonography.The appearance of vagina and perivaginal structures was observed from vaginal vault to orifice in transversal 3D reconstruction image of pelvic floor.Results Three-dimensional pelvic floor ultrasound showed cross-sectional imaging of the whole vagina clearly.The vaginal transversal morphologies were different at different level.It was lip-like in proximal vagina,butterfly-like in middle vagina and crescent-like in distal vagina.The perivaginal structures at different level were different.Perineal body was at distal vagina level,urethrovaginal septum,rectovaginal septum and paravaginal support at middle vagina level,perivaginal connective tissue at proximal vagina level.All were uniform,dense and complete.Conclusions The 3D pelvic floor ultrasound images of vagina and perivaginal structures at different level are distinct,which is valuable for the study of 3D ultrasound in female pelvic support and pelvic floor dysfunction.%目的 探讨未产妇不同水平阴道横断面及周围结构的三维盆底超声表现,为女性盆底支持结构的形态学观察提供有效的影像学方法 .方法 对50例无生育史年轻女性进行三维盆底超声检查,获得盆底横断面声像图,连续观察宫颈外口至阴道外口间阴道横断面及周围结构的声像图表现.结果 三维盆底超声清晰显示阴道全程的横断面声像图.不同水平的阴道横断面形态不同:近段阴道呈"唇形",中段阴道呈"蝶形",远段阴道呈"月牙形".不同水平的阴道周围结构不同:远段阴道水平可见会阴体,中段阴道水平可见尿道阴道隔、直肠阴道隔及阴道旁支持结构,近段阴道水平可见阴道周围结缔组织,阴道周围

  11. Analysis of microbial flora in dairy cow's vagina, and the isolation and identification of lactobacillus%奶牛阴道菌群分析与乳酸菌的分离及鉴定

    侯荣伦; 程超; 付艳茹; 刘彦民; 李利平; 郝永清; 黄少磊

    2011-01-01

    目的 研究奶牛阴道菌群,并从健康奶牛阴道分离出产酸能力很强的乳酸菌.方法 采用常规的方法对奶牛阴道进行细菌的分离及鉴定,并进行菌群分析.结果 健康奶牛阴道优势菌群主要为乳酸菌(P<0.01),屡配不孕奶牛阴道优势菌群主要为金黄色葡萄球菌(P<0.01);从健康奶牛阴道分离出的乳酸菌为55株,其中产酸能力很强的6株乳酸菌鉴定结果分别为Lactobacillus plantarum,Lactobacilluz brevis,Enterococcus faecalis,Lactococcus garvieae、Lactobacillus kitasatonis和Lactobacillus amylovorus.结论 奶牛阴道菌群中分离的6株乳酸菌可作为潜在的奶牛阴道微生态制剂进行深入研究.%Objective To Analyse the microbial flora in dairy cow's vagina, isolate and identify Lactobacillus with strong acid-producing capacity from vagina of healthy dairy cows. Method The standard microbiological methods were used to isolate and identify the bacteria in dairy cow's vagina. Result The most dominant bacteria in the vagina of healthy dairy cows belonged to Lactobacillus( P <0.01 ); The most dominant bacteria in the vagina of infertile dairy cows belonged to Staphylococcus aureus(P < 0.01 ); 55 lactic acid bacteria were isolated from the vagina of healthy dairy cows. 6 of which with strong acid-producing capacity were further identified as Lactobacillus plantarum, Lactobacillus brevis, Enterococcus faecalis, Lactococcus garvieae, Lactobacillus kitasatonis and Lactobacillus amylovorus, respectively. Conclusion The 6 lactic acid bacteria strains can be used as the candidates for the preparation of microecological additives of dairy cows and need further study.

  12. An evaluation of the amount of nonoxynol-9 remaining in the vagina up to 4 h after insertion of a vaginal contraceptive film (VCF) containing 70 mg nonoxynol-9.

    Mauck, C K; Allen, S; Baker, J M; Barr, S P; Abercrombie, T; Archer, D F

    1997-08-01

    The objectives of this study were to determine the amount of nonoxynol-9 (N-9) remaining in the vagina 30 min and 1, 1.5, 2, and 4 h after vaginal insertion of a single sheet of VCF containing 70 mg N-9 and to compare these results to the manufacturer's instructions for use of this product. A new method of vaginal lavage was used to obtain samples for N-9 determination. This was an open-label, noncomparative, pharmacokinetic study in 12 healthy women volunteers not at risk for pregnancy. The study consisted of a screening visit followed by five test visits approximately 1 month apart and a final visit 1 week after all test visits were completed. At each test visit, the investigator inserted a single sheet of VCF in the vagina of the volunteer at midcycle. The volunteer remained in the clinic and underwent vaginal lavage with normal saline after one of five specified time intervals had elapsed. The sequence of the intervals completed by each volunteer was determined by randomization. When undissolved film was found in the vagina, it was removed prior to lavage and assayed for N-9 content separately from that recovered in lavage fluid. It was assumed that the N-9 in undissolved film would not contribute significantly to sperm immobilization. Between 18.5 and 28.5 mg of N-9 were recovered in lavage fluid after intervals of 0.5, 1, 1.5, and 2 h. These levels did not differ statistically (p > 0.05). The amount of N-9 recovered dropped significantly at 4 h to 11.0 mg. If it is assumed that an N-9 concentration of 0.100 mg/mL is required to immobilize sperm in vitro, this study suggests that the amount of N-9 remaining in the vagina in the form of dissolved film up to 4 h after insertion of VCF is sufficient to immobilize sperm. The lavage procedure may not have recovered all N-9 remaining in the vagina. However, intercourse did not take place between insertion and lavage; if it had, the proportion of the film remaining undissolved and the total amount N-9 remaining in

  13. 瘢痕子宫瘢痕妊娠阴道彩超的检查%Scar Uterine Scar Pregnancy Vagina Colour to Exceed Examination

    袁雪英

    2013-01-01

    Objective:To explore the vagina colour to exceed to check for improving the significance of treatment of scar uterine scar pregnancy. Method:82 cases of cesarean section with postpartum scar pregnancy were retrospectively analyzed in our hospital from March 2010 to May 2013,and were randomly divided into two groups:observation group for vagina colour to exceed examination of patients,42 cases;the control group for patients with abdominal colour to exceed,40 cases. Compared the diagnostic coincidence rate of two groups. Result:Observation group diagnostic coincidence rate was 95.24%(40/42),the control group was 67.50%(27/40),the two groups had statistical significance(P<0.05);the missed diagnosis rate was 2.38%(1/42) in observation group,the control group was 12.50%(5/40).Conclusion:Transvaginal doppler colour to exceed examination can accurately positioning scar pregnancy surgical site,and damage to patients is small,less complications,is of great significance in clinic,is worth promoting.%目的:探讨阴道彩超检查对于提高治疗瘢痕子宫瘢痕妊娠的重要意义。方法:回顾性分析2010年3月-2013年5月本院收治的82例剖宫产产后瘢痕妊娠患者临床资料,随机分为两组,观察组42例进行阴道彩超检查,对照组40例进行腹部彩超检查。比较两组诊断符合率。结果:观察组诊断符合率95.24%(40/42),高于对照组的67.50%(27/40),两组比较差异具有统计学意义(P<0.05);观察组漏诊率2.38%(1/42)低于对照组的12.50%(5/40)。结论:经阴道多普勒彩超的检查能够准确的定位瘢痕妊娠的手术部位,在临床上具有重要意义,值得推广。

  14. Effects of depomedroxyprogesterone acetate on the development and maintenance of Candida albicans in the vagina of oophorectomized Wistar rats (Rattus norvegicus

    Agenor Storti-Filho

    2011-03-01

    Full Text Available The objective of this study was to determine the effect of medroxyprogesterone acetate (DMPA on the development and maintenance of Candida albicans in the vagina of oophorectomized Wistar rats. The animals were divided into negative control groups (NCG, which received injections of sterile saline; positive control groups (PCG, which were given injections of estradiol valerate; and progesterone groups (PG, which were given injections of Depo-Provera®. After one week of hormonal induction, vaginal infection by C. albicans was induced in all the groups and detected by vaginal yeast culture and Papanicolaou smear. In addition, scanning and transmission electron microscopy images were obtained to confirm the vaginal infection by yeast in PG. A difference in progesterone levels in PG was observed between the basal level and after hormonal induction (PO objetivo do presente estudo foi determinar os efeitos do acetato de depomedroxyprogesterona (ADMP no desenvolvimento e manutenção de Candida albicans na vagina de ratas Wistar ooferectomizadas. Os animais foram divididos em grupos controle negativos (GCN, que receberam injeções de salina estéril; grupos controle positivos (GCP, que receberam injeções de valerato de estradiol; e grupos progesterona (GP, nos quais foram feitas injeções de Depo-Provera®. Após uma semana da aplicação hormonal, foi induzida a infecção vaginal por C. albicans em todos os grupos, detectada por cultura para leveduras vaginais e esfregaço de Papanicolaou. Foram feitas ainda imagens por microscopia eletrônica de varredura e transmissão para confirmar a infecção pela levedura no GP. Foram observados diferentes níveis de progesterona em GP, entre os valores basais e após a indução hormonal (P<0,0001. Neste grupo, 100,0% das ratas contraíram a infecção vaginal na primeira semana, mas não a mantiveram até a terceira semana. A forma farmacêutica de ADMP foi efetiva em induzir as fases de metaestro e

  15. Atopobium vaginae与细菌性阴道病关系的研究%Study on the association of Atopobium vaginae with bacterial vaginosis

    张彦; 宋磊

    2007-01-01

    目的:应用非培养方法研究Atopobium vaginae与细菌性阴道病的关系.方法:根据Nugent评分标准从15例健康妇女及17例BV患者的其阴道分泌物中提取细菌总DNA.分别选择健康妇女及BV患者样本各3例,构建16S rRNA基因克隆文库并进行测序分析.应用Atopobium vaginae16S rRNA基因的特异性引物对32例样本进行PCR扩增.结果:Atopobium vaginae是BV患者阴道菌群中的优势菌种,它存在于大部分(14/17)BV患者阴道中,健康妇女阴道中(1/15)则很罕见.结论:Atopobium vaginae与细菌性阴道病的发生有一定的相关性.

  16. Inhibition of HIV-1 infection in ex vivo cervical tissue model of human vagina by palmitic acid; implications for a microbicide development.

    Xudong Lin

    Full Text Available BACKGROUND: Approximately 80% of all new HIV-1 infections are acquired through sexual contact. Currently, there is no clinically approved microbicide, indicating a clear and urgent therapeutic need. We recently reported that palmitic acid (PA is a novel and specific inhibitor of HIV-1 fusion and entry. Mechanistically, PA inhibits HIV-1 infection by binding to a novel pocket on the CD4 receptor and blocks efficient gp120-to-CD4 attachment. Here, we wanted to assess the ability of PA to inhibit HIV-1 infection in cervical tissue ex vivo model of human vagina, and determine its effect on Lactobacillus (L species of probiotic vaginal flora. PRINCIPAL FINDINGS: Our results show that treatment with 100-200 µM PA inhibited HIV-1 infection in cervical tissue by up to 50%, and this treatment was not toxic to the tissue or to L. crispatus and jensenii species of vaginal flora. In vitro, in a cell free system that is independent of in vivo cell associated CD4 receptor; we determined inhibition constant (Ki to be ∼2.53 µM. SIGNIFICANCE: These results demonstrate utility of PA as a model molecule for further preclinical development of a safe and potent HIV-1 entry microbicide inhibitor.

  17. Citologia Hormonal do Trato Urinário Baixo e da Vagina de Mulheres na Pós-menopausa, antes e durante Estrogenioterapia Oral e Transdérmica

    Lustosa Áurea Belas; Girão Manoel João Batista Castello; Sartori Marair Gracio Ferreira; Baracat Edmund Chada; Lima Geraldo Rodrigues de

    2002-01-01

    Objetivo: avaliar a ação dos estrogênios por via oral ou transdérmica nas células do trato urinário baixo e da vagina, em mulheres menopausadas. Métodos: foram incluídas 25 mulheres na pós-menopausa, nas quais se estudaram os efeitos citológicos da terapia de reposição hormonal estrogênica, por via oral e por via transdérmica, sobre as células da vagina e do sedimento urinário. As pacientes foram distribuídas aleatoriamente em 2 grupos: Grupo I, constituído por 14 mulheres que receberam 0,625...

  18. Avaliação dosimétrica de uma combinação de aplicadores para braquiterapia de tumores do colo uterino com acometimento da porção distal da vagina Dosimetric evaluation of a combination of brachytherapy applicators for uterine cervix cancer with involvement of the distal vagina

    Roger Guilherme Rodrigues Guimarães

    2009-08-01

    Full Text Available OBJETIVO: Avaliar uma alternativa de braquiterapia para tumores do colo uterino acometendo a porção distal da vagina, sem aumentar os riscos de toxicidade. MATERIAIS E MÉTODOS: Estudo teórico comparando três diferentes aplicadores de braquiterapia intracavitária de alta taxa de dose: sonda intrauterina e cilindro vaginal (SC; sonda e anel associado ao cilindro vaginal (SA+C e um aplicador virtual com sonda, anel e cilindro vaginal em um único conjunto (SAC. Foram prescritas doses de 7 Gy no ponto A e 5 Gy na superfície ou a 5 mm de profundidade na mucosa vaginal, mantendo as doses nos pontos de reto, bexiga e sigmoide abaixo dos limites de tolerância. Foram comparados os volumes englobados pelas isodoses de 50% (V50, 100% (V100, 150% (V150 e 200% (V200, respectivamente. RESULTADOS: Tanto SA+C quanto SAC apresentaram melhor distribuição de dose quando comparados ao aplicador SC. A distribuição de dose obtida com SA+C foi semelhante à do aplicador SAC, sendo V150 e V200 cerca de 50% maiores para SA+C, todavia, dentro do cilindro. CONCLUSÃO: A utilização de SA+C em uma única aplicação em dois tempos pode ser uma alternativa de tratamento para pacientes que apresentam tumores de colo uterino com acometimento distal da vagina.OBJECTIVE: To evaluate an alternative brachytherapy technique for uterine cervix cancer involving the distal vagina, without increasing the risk of toxicity. MATERIALS AND METHODS: Theoretical study comparing three different high-dose rate intracavitary brachytherapy applicators: intrauterine tandem and vaginal cylinder (TC; tandem/ring applicator combined with vaginal cylinder (TR+C; and a virtual applicator combining both the tandem/ring and vaginal cylinder in a single device (TRC. Prescribed doses were 7 Gy at point A, and 5 Gy on the surface or at a 5 mm depth of the vaginal mucosa. Doses delivered to the rectum, bladder and sigmoid colon were kept below the tolerance limits. Volumes covered by the

  19. 唯阴康预防宫颈癌放射治疗阴道并发症的观察%Wei yin kang to prevent cervical cancer radiotherapy vagina observation of complications

    杨爱青

    2015-01-01

    目的:对宫颈癌放射治疗的患者应用唯阴康预防放射性阴道并发症的效果观察。方法选择2008年3月至2012年12月宫颈癌患者160例,随机分为2组,80例为观察组,80例为对照组,对照组每日常规给予阴道冲洗,观察组,每日常规给予阴道冲洗后隔日给予阴道填塞唯阴康1支,共2个月,第3个月每周用2支。结果观察组使用唯阴康后阴道并发症明显低于对照组。%Objective:To apply only in patients with cervical cancer radiotherapy of Yin, prevention of complications of the vagina effect observation. Methods:March 2008-December 2012 160 cases of cervical cancer patients, randomly divided into 2 groups, 80 cases in observation group, 80 cases as control group, control group a daily routine for vagina washing, observation group, a day after the daily routine for vagina washing give vaginal tamponade wei Yin kang 1, 2 months, 3 months, two a week. Results:the observation group USES the vagina after wei Yin kang complications were significantly lower than the control group.

  20. Total cystectomy and subsequent urinary diversion to the prepuce or vagina in dogs with transitional cell carcinoma of the trigone area: A report of 10 cases (2005–2011)

    Saeki, Kohei; Fujita, Atsushi; Fujita, Naoki; Nakagawa, Takayuki; NISHIMURA, Ryohei

    2015-01-01

    The cases of 10 dogs with transitional cell carcinoma of the urinary bladder that underwent total cystectomy were retrospectively reviewed to evaluate the feasibility and outcome of total cystectomy and ureteral transplantation to the prepuce or vagina. Dehiscence of ureterostomy (n = 2), pyelonephritis (n = 3), oliguria (n = 2), azotemia (n = 1), and ureteral obstruction (n = 1) were observed complications. The estimated median survival time was 385 days. This study demonstrates the feasibil...

  1. Detection of the Human 70-kD and 60-kD Heat Shock Proteins in the Vagina: Relation to Microbial Flora, Vaginal pH, and Method of Contraception

    P. Giraldo

    1999-01-01

    Full Text Available The expression of the 60-kD and 70-kD heat shock proteins (hsp60 and hsp70 in the vaginas of 43 asymptomatic women of reproductive age with or without a history of recurrent vulvovaginitis (RVV were compared. Vaginal wash samples were obtained and assayed by enzyme-linked immunosorbent assay (ELISA for human hsp60 and hsp70. Heat shock protein 70 was not detected in any of the 19 women with no history of RVV, and hsp60 was present in only one woman in this group. In contrast, in the RVV group, 11 (45.8% were hsp60-positive and eight (33.3% were hsp70-positive. The presence of either heat shock protein in the vagina was associated with an elevated vaginal pH (>4.5. Bacterial vaginosis or Candida was identified in some of the asymptomatic subjects; their occurrence was significantly higher in women with vaginal hsp70 than in women with no heat shock proteins. Oral contraceptives were used by 35.7% of subjects who were negative for vaginal heat shock proteins, as opposed to only 12.5% of women who were positive for hsp70 and 8.3% who were positive for hsp60. Expression of heat shock proteins in the vagina may indicate an altered vaginal environment and a susceptibility to vulvovaginal symptoms. Infect. Dis. Obstet. Gynecol. 7:23–25, 1999.

  2. Detection of the human 70-kD and 60-kD heat shock proteins in the vagina: relation to microbial flora, vaginal pH, and method of contraception.

    Giraldo, P; Neuer, A; Ribeiro-Filho, A; Linhares, I; Witkin, S S

    1999-01-01

    The expression of the 60-kD and 70-kD heat shock proteins (hsp60 and hsp70) in the vaginas of 43 asymptomatic women of reproductive age with or without a history of recurrent vulvovaginitis (RVV) were compared. Vaginal wash samples were obtained and assayed by enzyme-linked immunosorbent assay (ELISA) for human hsp60 and hsp70. Heat shock protein 70 was not detected in any of the 19 women with no history of RVV, and hsp60 was present in only one woman in this group. In contrast, in the RVV group, 11 (45.8%) were hsp60-positive and eight (33.3%) were hsp70-positive. The presence of either heat shock protein in the vagina was associated with an elevated vaginal pH (>4.5). Bacterial vaginosis or Candida was identified in some of the asymptomatic subjects; their occurrence was significantly higher in women with vaginal hsp70 than in women with no heat shock proteins. Oral contraceptives were used by 35.7% of subjects who were negative for vaginal heat shock proteins, as opposed to only 12.5% of women who were positive for hsp70 and 8.3% who were positive for hsp60. Expression of heat shock proteins in the vagina may indicate an altered vaginal environment and a susceptibility to vulvovaginal symptoms. PMID:10231004

  3. The clinical study of the extensive hysterectomy vagina yarn after anesthesia%广泛全子宫切除术前实施麻醉后行阴道塞纱的临床研究

    黄兰英; 陈少君; 刘萍凤; 康淑泉

    2014-01-01

    目的:探讨广泛全子宫切除术前实施麻醉后行阴道塞纱的效果。方法选择行广泛全子宫切除术患者60例,设对照组和实验组各30例,对照组实施有针对性阴道塞纱,实验组实施麻醉后行阴道塞纱。术后由手术医生对2患者术前阴道塞纱的效果进行评估,并在术后1天采用自行设计的患者满意度调查表对两组病人进行调查。结果实施麻醉后行阴道塞纱效果优于对照组(χ2=6.66,P !0.01),实验组患者与对照组患者满意度调查相比差异有统计学意义(χ2=38.46,P !0.01)。结论广泛全子宫切除术前实施麻醉后行阴道塞纱更能体现人性化服务,可提高手术效果,减少手术并发症,提高医疗护理质量。%Objective To investigate the effect of the extensive hysterectomy vagina yarn after anesthesia.Method 60 patients with extensive hysterectomy were selected which were divided into control group and experimental group.Control group implement the targeted vagina gauze, while the experimental group implement vagina yarn after anesthesia.The doctors evaluated the effect of the patient’s vagina yarn on two the groups after the intervention.The patient satisfaction questionnaire was used on two the groups of patients in the investigation.ResultsThe results of the experimental group is better than the control group(χ2 =6.66,P<0.01 ).The difference between the experimental group patients and the control group patients’satisfaction was statistically significant.Conclusion Extensive hysterectomy vagina yarn after anesthesia is more human-ized service and it is beneficial to improve the effect of surgery and reduce complications and improve the quality of medical care.

  4. Cervix high-risk HPV infection and vagina environment correlation factor analysis%宫颈高危HPV感染与阴道内环境相关因素分析

    于妍妍; 金哲; 刘艳霞; 黄文玲; 曹颖

    2011-01-01

    Objective To investigate the relationship between vaginal environment change and the cervix high-risk human papilloma virus ( HR-HPV ) infects. Methods 250 female patients were enrolled and received HPV-DNA examination. The woman's vagina secretion were tested by using the vagina secretion method of pendant drop and the Gram dyeing, the fast BV examination reagent box method, the pH indicator paper determination method separately, the results of the vaginitis, vagina cleanliness, vagina pH value, vagina bacteria colony were tested and recorded. Results HPV-DNA results showed that positive results in 124 cases and negative in 126 cases. The Logistic regression analysis results indicated that the pH value, the bacteria colony change and bacterial vaginosis were the HR-HPV infection hazard factor ( OR value were 2. 883, 1. 547 and 2. 409 respectively, P <0. 05 ). the cleanliness, infusoria vaginitis and rayon saccharomycetes vaginitis were not the HR-HPV infection hazard factor( P >0.05 ). Conclusion The pH value, the bacteria colony change and the bacterial vaginosis are the HR-HPV infection hazard factors, but the cleanliness, the infusoria vaginitis and the rayon saccharomycetes vaginitis are not the HR-HPV infection hazard factors.%目的 探讨阴道内环境的变化与宫颈高危人乳头瘤病毒(HR-HPV)感染之间的关系.方法 入选250例女性,进行HPV DNA检测,取阴道分泌物分别采用阴道分泌物悬滴法、Gram染色法、快速BV检测试剂盒法,测阴阴道炎和检道内环境的指标(阴道清洁度、阴道pH值、阴道菌群组成).结果 250例女性中HR-HPV阳性124例、阴性126例.Logistic回归分析结果表明,pH值、菌群变化及细菌性阴道病是HR-HPV感染的危险因素(OR值分别为2.883、1.547、2.409,P均0.05).结论 pH值、菌群变化及细菌性阴道病是HR-HPV感染的危险因素,而清洁度、滴虫性阴道炎及假丝酵母菌阴道炎不是HR-HPV感染的危险因素.

  5. Detection of hydrogen peroxide-producing Lactobacillus species in the vagina: a comparison of culture and quantitative PCR among HIV-1 seropositive women

    Balkus Jennifer E

    2012-08-01

    Full Text Available Abstract Background The presence of hydrogen peroxide (H2O2 producing Lactobacillus in the vagina may play a role in controlling genital HIV-1 shedding. Sensitive molecular methods improve our ability to characterize the vaginal microbiota; however, they cannot characterize phenotype. We assessed the concordance of H2O2-producing Lactobacillus detected by culture with quantitative PCR (qPCR detection of Lactobacillus species commonly assumed to be H2O2-producers. Methods Samples were collected as part of a prospective cohort study of HIV-1 seropositive US women. Cervicovaginal lavage specimens were tested for L. crispatus and L. jensenii using 16S rRNA gene qPCR assays. Vaginal swabs were cultured for Lactobacillus and tested for H2O2-production. We calculated a kappa statistic to assess concordance between culture and qPCR. Results Culture and qPCR results were available for 376 visits from 57 women. Lactobacilli were detected by culture at 308 (82% visits, of which 233 of 308 (76% produced H2O2. L. crispatus and/or L. jensenii were detected at 215 (57% visits. Concordance between detection of L. crispatus and/or L. jensenii by qPCR and H2O2-producing Lactobacillus by culture was 75% (kappa = 0.45. Conclusions Among HIV-1 seropositive women, there was a moderate level of concordance between H2O2-producing Lactobacillus detected by culture and the presence of L. crispatus and/or L. jensenii by qPCR. However, one-quarter of samples with growth of H2O2-producing lactobacilli did not have L. crispatus or L. jensenii detected by qPCR. This discordance may be due to the presence of other H2O2-producing Lactobacillus species.

  6. The effect of copaiba balsam on Walker 256 carcinoma inoculated into the vagina and uterine cervix of female rats Efeito do óleo de copaíba no tumor de Walker 256 inoculado em vagina e colo de útero de ratas fêmeas

    Nara Macedo Botelho Brito

    2010-04-01

    Full Text Available PURPOSE: To verify the copaiba balsam (Copaifera officinalis effect on Walker 256 carcinoma inoculated into vagina and uterine cervix of rats. METHODS: Eighteen female Wistar rats weighing between 180-250g were used, distributed into 2 groups (GCop, GC. On the 1st day of the experiment, 0.3 ml of Walker 256 carcinoma (2x10(6 concentration was inoculated in both groups; on the 3rd day of the experiment, it was given 4.8 ml/kg of distilled water to the GC group, and 4.8 ml/kg of copaiba balsam to the GCop group. On the 12th day, euthanasia was performed and the tumor was grafted, being weighted and verified its volume. The data were submitted to statistical analysis with ANOVA test. RESULTS: It was observed that copaiba balsam presented a negative inhibitory potential of 70%. CONCLUSION: The copaiba balsam stimulated the tumor growth.OBJETIVO: Verificar o efeito do óleo de copaíba da espécie Copaifera officinalis no carcinoma de Walker 256 inoculado em vagina e colo de útero de ratas. MÉTODOS: Foram utilizadas 18 ratas da linhagem Wistar, pesando entre 180-250g, distribuídas em dois grupos (CCop, GC. No 1º dia de experimento, em ambos os grupos foi inoculado 0,3ml de tumor de Walker 256 na concentração de 2x10(6; no 3º dia após essa inoculação, foi iniciada a administração de água destilada na dose de 4,8 ml/kg ao GC, e copaíba na dose de 4,8 ml/kg ao GCop. No 12º dia foi realizada a eutanásia das ratas e ressecado o tumor, sendo este pesado e averiguado seu volume. Os dados obtidos foram submetidos à análise estatística pelo método ANOVA. RESULTADOS: Observou-se que o óleo de copaíba apresentou um potencial inibitório negativo de 70%. CONCLUSÃO: O óleo de copaíba estimulou o crescimento tumoral.

  7. 乙状结肠代阴道成形术治疗先天性无阴道的疗效分析%Clinical effect of sigmoid colon vaginoplasty in treatment of congenital absence of vagina

    唐素蓉; 藤青芳; 张晓丹

    2014-01-01

    Objective To discuss the clinical effect of sigmoid colon vaginoplasty in the treatment of patients with congenital absence of vagina. Methods 4 patients with the congenital absence of vagina treated in this hospital from February 2011 to August 2013 received the treatment of sigmoid colon vaginoplasty. Their average operation time, intraoperative hematoma volume, postoperative complications and postoperative vaginal structure and function were observed. Results 4 patients with the congenital absence of vagina who received the sigmoid colon vaginoplasty were all successful in the operation, with the average operation time of (140.5±26.5)min and average hematoma volume of (118.4±4.5)mL. The vagina formed by the sigmoid colon surgery was close to the normal one in the shape and patients were satisfied with the sex life without any intraoperative or postoperative complication. Conclusion After receiving the sigmoid colon vaginoplasty, patients with the congenital absence of vagina have their operation-formed vaginas basically similar to normal ones in the structure and function. It is characterized by the safe operation, short operation time, limited hematoma volume and little complications, which is worthy to be popularized in the clinical practice.%目的:研究探讨应用乙状结肠代阴道成形术治疗先天性无阴道患者的临床疗效。方法对我院2011年2月~2013年8月收治的先天性无阴道患者4例进行分析,采用乙状结肠代阴道成形术治疗,观察4例采用乙状结肠代阴道成形术的平均手术时间、手术时出血量、手术后的并发症以及手术后阴道的结构和功能的情况。结果采用乙状结肠代阴道成形术治疗的4例先天性无阴道患者手术均获得成功,而且手术的平均时间为(140.5±26.5)min,平均出血量为(118.4±4.5)mL。用乙状结肠手术成的阴道在形态上与正常女性阴道接近,并且患者性生活感觉满意,没有发生手

  8. Character of Psychology of Patients with Congenital Absence of Vagina during Preoperative Period and Nursing Strategy%先天性无阴道患者围手术期心理特点及护理对策

    王小丽

    2011-01-01

    目的探讨先天性无阴道患者围手术期有效的护理措施,提高护理质量.方法:针对患者不同的心理状态进行分类,给予心理辅导,提供相关信息,做出相应的护理对策.结果:43 例患者均痊愈出院,无护理并发症的发生.结论:有效的围手术期护理是手术成功的重要因素之一,应根据患者的病情及心理特点,采取有针对性的护理措施,减轻和消除患者不良的心理反应,促进健康的恢复.本文通过对先天性无阴道患者围手术期心理特点的观察,提出相应的护理措施,并很好地运用于临床.%Objective: To investigate the nursing strategy for patients with congenital absence of vagina during preoperative period in order to improve quality of nursing. Methods: According to different characteristics of psychology of patients, patients were administered with psychological consulting and related nursing strategy.Results: 43 of patients were fully recovery from congenital absence of vagina without complication. Conclusion: Effective nursing during preoperative period is a critical factor for successful surgery. According to different condition and character of psychology of patients, related nursing intervention was administered to relieve negative psychological condition and promote recovery from illness.Out study presented that that it was effective of using of psychological nursing intervention to patients with congenital absence of vagina in clinical work.

  9. 消糜阴道泡腾片对大鼠细菌性阴道炎的治疗作用研究%Experimental study on the effect of Xiaomi Vagina Effervescent Tablets on bacterial vaginitis in rats

    姜善玲; 王平; 李百开; 高雁

    2014-01-01

    目的:探讨消糜阴道泡腾片对大鼠细菌阴道炎模型的治疗作用。方法将雌性大鼠随机分为正常对照组、模型组、消糜阴道泡腾片治疗组、氧氟沙星栓剂对照组。除正常对照组外,其余各组大鼠建立细菌性阴道炎模型,成模后给药,末次药后取阴道分泌物涂片染色镜检验;处死大鼠,取阴道组织,进行病理学的检查。结果消糜阴道泡腾片高剂量抗大鼠细菌性阴道炎的总有效率为91.7%,与氧氟沙星栓组比较无统计学意义(P ﹥0.05)。结论消糜阴道泡腾片对大鼠细菌性阴道炎具有显著的治疗作用。%Objective To investigate the therapeutic effects of Xiaomi Vagina Effervescent Tablets on bacteria vaginitis model in rats. Methods Female rats were randomly divided into normal control group,model group,Xiaomi Vagina Effer-vescent Tablets treatment group,Ofloxacin Suppositories control group. Except normal control group,establishment of bacte-rial vaginitis model in the remaining rats,into the mold after the administration,after last administration,vaginal secretion smear staining microscopic examination;The rats were sacrificed,and vaginal tissue was took to carry out pathologic exami-nation. Results The high dose of Xiaomi Vagina Effervescent Tablets in rats with bacterial vaginosis total efficiency was 91. 7% ,there was no statistical significance compared with the Ofloxacin Suppositories group(P ﹥ 0. 05). Conclusion Xiaomi Vagina Effervescent Tablets in the treatment of bacterial vaginosis rats had significantly therapeutic effect.

  10. Vaginoplasty with an Acellular Dermal Matrix Patch for Congenital Absence of Vagina%生物补片人工阴道成形术治疗先天性无阴道

    贡震; 邵振堂; 沈宇飞; 张蕾; 石晓燕; 谭笑梅

    2014-01-01

    Objective To evaluate the clinical application of vaginoplasty with an acellular dermal matrix patch in the treatment of congenital absence of vagina . Methods This retrospective analysis included 21 patients with congenital absence of vagina referred to our department from March 2010 to March 2013.All the patients underwent vaginoplasty at the gap between the rectum and the urethra with an acellular dermal matrix patch .The clinical course and management were reviewed . Results All the 21 patients underwent vaginoplasty with an acellular dermal matrix patch successfully .The vagina mucosa was formed 8 weeks after vaginoplasty with a depth >8 cm and width >3 cm.After follow-up reviews for 9-18 months, a satistactory feedback of sexual life was obtained in 14 patients who had sexual experiences . Conclusion Vaginoplasty with an acellular dermal matrix patch for patients with congenital absence of vagina can be successfully performed with satisfactory outcomes .%目的:探讨生物补片人工阴道成形术治疗先天性无阴道的疗效。方法2010年3月~2013年3月,行生物补片人工阴道成形术治疗21例先天性无阴道,于直肠及尿道膀胱间隙人工造穴,百得塞补片置入造穴腔,并指导患者定期更换模具。结果21例手术均获成功,术后8周人工阴道即完全黏膜化,阴道壁柔软、红润,阴道深度>8 cm,宽度>3横指。随访9~18个月,有性生活患者(14例)性生活满意。结论生物补片人工阴道成形术是治疗先天性无阴道的可行方法。

  11. 复发性外阴阴道假丝酵母菌病发病机制的研究进展%An analysis of the factors contributing to recurrent vulva and vagina candidiasis

    徐倩倩; 宁玉梅

    2013-01-01

    复发性外阴阴道假丝酵母菌病(Recurrent candidiasis of vulva and vagina,RVVC)病因复杂,主要原因有机体免疫防御机制的变化,宿主局部因素,假丝酵母菌的菌群多样性变化等.认识、了解及掌握上述因素,对临床工作者有效防治RVVC起着非常重要作用.

  12. Detection of the Human 70-kD and 60-kD Heat Shock Proteins in the Vagina: Relation to Microbial Flora, Vaginal pH, and Method of Contraception

    Giraldo, P.; Neuer, A.; Ribeiro-Filho, A; Linhares, I; Witkin, S. S.

    1999-01-01

    The expression of the 60-kD and 70-kD heat shock proteins (hsp60 and hsp70) in the vaginas of 43 asymptomatic women of reproductive age with or without a history of recurrent vulvovaginitis (RVV) were compared. Vaginal wash samples were obtained and assayed by enzyme-linked immunosorbent assay (ELISA) for human hsp60 and hsp70. Heat shock protein 70 was not detected in any of the 19 women with no history of RVV, and hsp60 was present in only one woman in this group. In contrast, in the RVV gr...

  13. “If your vagina could speak, what would it say?”: Dangerous Femininity, Anxious Masculinity and the Threat of Female Desire in the 1975 Pornographic Movie "The Sex that Speaks"

    Garrigou-Kempton, Emilie

    2010-01-01

    The Sex that Speaks, also known in English as Pussy Talks, relates the story of a woman whose vagina inexplicably starts talking and reveals a voracious sexual appetite. In The Indiscreet Jewels, the “jewels” of several women start talking as one man, curious about female sexuality, interrogates them. In both cases, the talking sex is always female and it consistently delivers a uniform message of women’s sexual promiscuity. It is this recurring curiosity, as well as the uniformity of the mes...

  14. Clinical observation of filling type suture via vagina on rectocele%经阴道填充式修补术治疗直肠前突的疗效观察

    刘进中; 李俊英

    2012-01-01

    目的 观察经阴道填充式修补术治疗中、重度直肠前突的临床疗效.方法 对21例直肠前突病例资料进行回顾性分析.结果 治愈14例(66.7%),显效4例(19.0%),有效3例(14.3%),无效0例(0.0%).住院13~21 d,无并发症及后遗症.结论 经阴道填充式修补术治疗直肠前突,临床疗效满意,安全可靠,值得临床推广.%Objective To observe the clinical efficacy of filling type suture via vagina on moderate and severe rectoeele (RC). Methods The clinical data of 21 RC patients were retrospectively analyzed. Results Fourteen patients (66.7%) were cured. The therapeutic effect was excellent in 4 patients (19.0%), and good in 3 (14.3%). No ineffective case was recorded. The length of hospital stay was 13 to 21 d with no complications and sequelae. Conclusion The filling type suture via vagina on RC can obtain satisfying clinical outcomes. It's safe, reliable, and worth to be popularized.

  15. Progress in research of vagina micro ecological imbalance in Chinese and Western medicine%阴道微生态失调的中西医研究进展

    王丹丹; 董燕

    2014-01-01

    Vaginal micro ecological imbalance refers to the normal flora imbalance of the vagina, including the result of the impact of external factors , the mutual restraint and interdependent among the original flora to broke the balance , causing abnormal vaginal discharge, genital itching or waist, a gynecological abdominal pain symptoms of vaginitis, vaginal as female genital connection with the outside world the only passage between the environment, the human body is an important micro­ecological zones. Is also an important part of the reproductive tract micro flora. In the vaginal wall mucosal folds and then there is the vault vaginal flora, usually vaginal flora with lactobacilli was the dominant bacteria. Into a variety of lactic acid bacteria, Lactobacillus probiotics for the maintenance of the vagina is important, PH value of the vagina can be maintained in the normal acidic condition, can also inhibit bacteria play a bactericidal effect, in addition to lactic acid bacteria in the vagina outside of further there are fungi, viruses, etc., under normal circumstances, a variety of flora in the vagina interdependent mutual restraint, joint action within the vaginal environment will be maintained at a balanced state, the dominant strain of Lactobacillus, once lost the advantage will lead to other flora overgrowth, breaking the vaginal micro flora balance, leading to female vaginal dysbiosis.%阴道微生态失调是指阴道中的正常的菌群在内因或在外因的影响下出现了菌群之间的失衡,使原来菌群之间的互相制约、互相依赖的平衡关系被打破,从而引起白带异常、外阴瘙痒或是腰部、下腹部疼痛[1]的阴道炎症状的一种妇科疾病。阴道作为连接女性内生殖器与外界环境之间唯一的通道,是人体内重要的微生态区,也是生殖道微生态的重要部分。在阴道的侧壁黏膜、皱襞,而后是穹窿都存在有阴道菌群,通常阴道菌群

  16. 葛石胶囊对去卵巢大鼠子宫和阴道的影响%The effects of Geshi capsule on womb and vagina in ovariectomized rats

    王诗华

    2011-01-01

    目的 明确葛石胶囊对主要分布雌激素α受体的子宫和阴道的影响.方法采用模拟人类妇女绝经期的雌性切除双侧卵巢大鼠模型,随机分成正常组、假手术组、模型组、雌激素组及葛石胶囊大、中、小剂量组.手术后第2周开始给药,持续6周.结果模型组子宫和阴道的湿重及指数明显减少;雌激素可使其增加至正常范围,葛石胶囊各组也可使其有不同程度增加,表现为高于模型组而同时低于正常组.模型组大鼠子宫的体积变小,管壁明显变薄,管腔狭窄,内膜下腺体减少,固有层细胞密集,同时,阴道壁明显变薄,黏膜上皮薄.雌激素组治疗后,子宫和阴道恢复到正常组水平;葛石胶囊大剂量组可部分改善去卵巢大鼠子宫和阴道的变化,但达不到正常组水平.中、小剂量组对所观察指标影响不大.结论葛石胶囊无显著促进去卵巢大鼠子宫和阴道增重及相关细胞增生的作用.提示临床应用葛石胶囊防治更年期妇女骨质疏松、心血管疾病及其能量代谢的同时,其诱发子宫和阴道的不良反应可能远低于雌激素.%OBJECTIVE To clarify the effect of Geshi capsule on womb and vagina, where estrogen a receptor was mainly expressed. METHODS The ovariectomized rats were randomly divided into the normal group, sham - operation group, model group, estrogen group,Geshi capsule with high,middle and low dose groups. Two weeks after surgery,the moded rats were treated for 6 weeks. RESULTS The wet weight and related index in the model group were significantly reduced, and could be increased to the normal range by estrogen. The value of these parameters after treated with Geshi capsule appeared to be higher than model group,but lower than normal group (P < 0.01). The morphology observation demonstrated that the size of womb became smaller and the vagina wall got thinner in model group. The womb and vagina could recover to normal state following

  17. 妊娠期外阴阴道念珠菌感染患者的临床治疗措施研究%Clinical treatment for vulva vagina candida infection during pregnancy

    张佳洁; 梁淑青

    2015-01-01

    Objectives:To summarize the clinical treatment and therapeutic efficiency of vulva vagina can-dida infection during pregnancy.Methods:82 pregnancy patients with vulva vagina candida infection treated in our hospital from February 201 2 to August 201 4 were selected and randomly divided into two groups.41 cases in control group received routine therapy,while 41 cases in the experimental group received targeted therapy plan.The thera-peutic efficiency of the two groups was compared.Results:The difference in treatment effect between the two groups was significant (P <0.05).Conclusion:Clinical treatment on clinical pregnancy vulva vagina candida infection must be timely and thorough.More attention should be given to drug choose,so as not to affect the fetus.At the same time,the use of antifungal drugs on the vulva vagina candida infection during pregnancy is prohibited.Vaginal topical drugs are the main choice to minimize influence on the fetus.%目的:总结妊娠期外阴阴道念珠菌感染患者的临床治疗措施与治疗效率。方法:本次研究资料选自2012年2月至2014年8月期间在我院接受诊治的82例妊娠期外阴阴道念珠菌感染患者,随机分成两组。对照组41例研究对象接受常规治疗,而实验组41例研究对象则接受针对性治疗方案,同时对比及分析两组研究对象的治疗情况。结果:两组研究对象在治疗效果方面的比较差异较为显著(P <0.05)。结论:临床上妊娠期外阴阴道念珠菌感染患者的临床治疗必须及时与彻底,并严格把握药物选用环节,以免对胎儿造成影响。同时,妊娠期外阴阴道念珠菌感染患者禁止使用抗真菌类药物,以阴道局部类药物为主要选择,最大限度控制对胎儿的影响。

  18. Endoluminal ultrasound and segmental analysis in diagnosis of congenital malformation of the uterus and vagina%腔内超声节段分析法诊断先天性子宫及阴道畸形

    杨雪冰; 王慧芳; 刘云平; 陈秋香; 郭娟; 王诗雅

    2013-01-01

    Objective To investigate the diagnostic value of endoluminal ultrasound (transvaginal and transrectal ultrasound) and segmental analysis with three-dimensional ultrasonography for congenital malformation of the uterus and vagina. Methods A total of 226 patients with clinically confirmed congenital malformations of the uterus and vagina were enrolled and divided into two groups. Group A included 154 cases, the findings of transabdominal or endoluminal two dimensional ultrasonography were retrospectively compared with clinical diagnosis. Group B included 72 cases, the results of segmental analysis by endoluminal three-dimensional ultrasonography were perspective studied and then compared with clinical diagnosis. Results In group A, 99 of 154 cases with congenital malformations of the uterus and vagina were diagnosed by two dimensional ultrasound, while 55 cases were missed or misdiagnosed. The coincidence rate was 64. 29% (99/154). In group B, since the introduction of three dimensional ultrasonography and segmental analysis, 69 of 72 cases were defined, with the coincidence rate of 95. 83% (69/72), while 3 cases were missed diagnosed or misdiagnosed. Conclusion Translu-minal three-dimensional ultrasonography and segmental analysis have essential diagnostic value, which can improve the accuracy of diagnosis and classification of congenital malformation of the uterus and vagina.%目的 探讨应用腔内(经阴道或经直肠)三维超声节段分析法诊断先天性子宫及阴道畸形的价值.方法 将226例先天性子宫及阴道畸形患者分为A、B两组.A组154例,采用回顾性分析,对比分析其经腹或腔内二维超声检查的结果及临床结局;B组72例,采用前瞻性研究,对比分析应用节段分析法经腔内三维超声检查的结果及临床结局.结果 A组154例中,二维超声检查诊断符合率为64.29%(99/154),漏、误诊55例,未进行详细分类;B组72例中,腔内三维超声节段

  19. Clinical treatment for vulva vagina candida infection during pregnancy%妊娠期外阴阴道念珠菌感染患者的临床治疗措施研究

    张佳洁; 梁淑青

    2015-01-01

    Objectives:To summarize the clinical treatment and therapeutic efficiency of vulva vagina can-dida infection during pregnancy.Methods:82 pregnancy patients with vulva vagina candida infection treated in our hospital from February 201 2 to August 201 4 were selected and randomly divided into two groups.41 cases in control group received routine therapy,while 41 cases in the experimental group received targeted therapy plan.The thera-peutic efficiency of the two groups was compared.Results:The difference in treatment effect between the two groups was significant (P <0.05).Conclusion:Clinical treatment on clinical pregnancy vulva vagina candida infection must be timely and thorough.More attention should be given to drug choose,so as not to affect the fetus.At the same time,the use of antifungal drugs on the vulva vagina candida infection during pregnancy is prohibited.Vaginal topical drugs are the main choice to minimize influence on the fetus.%目的:总结妊娠期外阴阴道念珠菌感染患者的临床治疗措施与治疗效率。方法:本次研究资料选自2012年2月至2014年8月期间在我院接受诊治的82例妊娠期外阴阴道念珠菌感染患者,随机分成两组。对照组41例研究对象接受常规治疗,而实验组41例研究对象则接受针对性治疗方案,同时对比及分析两组研究对象的治疗情况。结果:两组研究对象在治疗效果方面的比较差异较为显著(P <0.05)。结论:临床上妊娠期外阴阴道念珠菌感染患者的临床治疗必须及时与彻底,并严格把握药物选用环节,以免对胎儿造成影响。同时,妊娠期外阴阴道念珠菌感染患者禁止使用抗真菌类药物,以阴道局部类药物为主要选择,最大限度控制对胎儿的影响。

  20. Relevance between acidic environment of vagina and vulvovaginal Candidiasis%阴道内酸性环境对白色念珠菌性外阴阴道炎治疗的关联研究

    施磊; 宗黎琼; 童剑倩; 郭澄

    2012-01-01

    Objective To explore the relevance between the acidic environment of vagina and vulvovaginal Candidiasis infected by Candida albicans. Methods Ninety-six strains from patients (June 2009 to March 2010) with Simple Gynecological Candida Vulvovaginitis (SVVC) were isolated and identified. The MIC of miconazole and clotrimazole under different pH value of environment were measured. Results The MIC of miconazole or clotrimazole was decreased under lower pH value. Conclusion Keep the acidic environment of vagina is beneficial to the treatment of vulvovaginal Candidiasis infected by Candida albicans.%目的 探讨阴道内酸性环境与白色念珠菌性外阴阴道炎的相关性.方法 分别对2009年6月至2010年3月妇科门诊的单纯性外阴阴道假丝酵母菌病(SVVC)患者进行阴道菌株分离、鉴定,获得白色念珠菌96株.检测不同pH值环境下菌株对硝酸咪康唑与克霉唑的药物敏感性,并观察相关性.结果 在pH值偏酸性的环境下,两种唑类药物的MIC均有不同程度的降低,对白色念珠菌抑菌效果更强.结论 维持阴道内酸性环境能更有效地治疗白色念珠菌性外阴阴道炎.

  1. 剖宫产后阴道分娩35例相关因素分析%Splits the Palace Post-natal Vagina Childbirth 35 Example Correlation Factors to Analyze

    邹清如; 蔡芬兰; 黄利兰; 宋薇

    2012-01-01

      目的 探讨剖宫产术后阴道分娩(VBAV)的相关因素.方法 回顾性分析135例瘢痕子宫孕妇的临床资料,根据分娩方式分为阴道分娩组(实验组)35例和剖宫产组(对照组)100例,对孕妇的一般情况进行调查分析,并在两组之间进行对比.结果 两组产妇在阴道分娩史、前次剖宫产指征、胎龄、新生儿体质量、宫颈条件等方面有统计学差异(P0.05).结论 VBAV与多种因素有关,针对上述相关因素可适时选择阴道分娩,减少剖宫产率,提高产科质量.%  Objective After the goal discussion splits the palace to produce the technique the vagina childbirth (VBAV) correlation factor. Method Review analysis 135example scar womb pregnant woman's clinical material, divides into the vagina childbirth group according to the childbirth way (experimental group) 35 examples and splits the palace to produce the group (control group) 100 examples, carries on the diagnosis to pregnant woman's ordinary circumstances, and carries on the contrast between two groups. Result The two group of parturient women in the vagina childbirth history, recently split the palace to produce refer draft, aspects and so on embryo age, newborn body weight, cervix of the uterus condition have statistics difference (P0.05).Conclusion VBAV and many kinds of factors related, may at the right moment choose the vagina childbirth in view of the above correlation factor, reduces splits the palace production rate, improves obstetrics quality.

  2. The research progress of vagina lactobacillus is associated with cervical lesions%阴道乳杆菌与宫颈病变相关的研究进展

    辛秀团

    2015-01-01

    The cervical lesion is one of the major diseases threatening the health of women, in the context of its incidence, second only to breast cancer in female malignant tumor in the whole world, in some countries even than the breast cancer incidence of a disease. Mainly concentrated in cervical lesions in patients with age between 30 to 45 years old, and as the patient age incidence is obviously rising trend. At home and abroad at present, many scholars believe that the cervical lesions have direct links to the fall in the number of lactobacillus in the vagina, aimed at this situation, this study from the antitumor mechanism and original microbial antagonism disease-resistant two aspects of lactobacillus in the vagina and cervix lesion of correlation analysis, the peers to play the role of reference and reference.%宫颈病变是威胁妇女健康的主要疾病之一,就其发病率来看,在全球女性恶性肿瘤中仅次于乳腺癌,在部分国家中发病率甚至超过了乳腺癌。宫颈病变患者年龄主要集中在30-45岁之间,而且随着患者年龄的增长发病率呈明显上升趋势。目前,国内外诸多学者认为宫颈病变与阴道乳杆菌数量下降有着直接的联系,针对这一现状,本研究从抗肿瘤机制以及拮抗病原微生物两个方面对阴道乳杆菌与宫颈病变的相关性进行分析,希望能够对广大同行起到借鉴与参考的作用。

  3. MRI of the uterus, uterine cervix, and vagina: diagnostic performance of dynamic contrast-enhanced fast multiplanar gradient-echo imaging in comparison with fast spin-echo T2-weighted pulse imaging

    The aim of this study was to compare the diagnostic performance of contrast-enhanced fast multiplanar gradient-echo (GRE) and T2-weighted fast spin-echo (FSE) image sets in the assessment of uterus, cervix, and vagina. Fast (up to 20 contiguous sections in 23 s) multiplanar GRE and FSE images of 45 patients referred for imaging of the female pelvis were evaluated retrospectively with regard to overall image quality and the ability to detect normal anatomic structures, as well as lesion conspicuity. Results were compared with histologic findings (n = 29) or clinical follow-up. Furthermore, a quantitative assessment of contrast-to-noise ratios among normal uterine and cervical structures as well as uterine lesions was performed for both sequences. On GRE images, uterine and cervical differentiation was best seen on the image sets acquired 15 and 60 s following contrast enhancement and results were significantly better compared with delayed images (p 2 test, the difference in diagnostic performance between FSE and GRE revealed no significant difference, whereas the combination of both techniques performed better than FSE imaging alone (p < 0.05). The presented data suggest that dynamic contrast-enhanced GRE imaging should be part of an MR examination of the female pelvis. Combined GRE and FSE imaging provide an excellent sensitivity in the assessment of uterine and vaginal pathologies. (orig.) (orig.)

  4. Citologia Hormonal do Trato Urinário Baixo e da Vagina de Mulheres na Pós-menopausa, antes e durante Estrogenioterapia Oral e Transdérmica Urinary and Vaginal Cytology of Postmenopausal Women with Oral and Transdermal Estrogen Replacement

    Áurea Belas Lustosa; Manoel João Batista Castello Girão; Marair Gracio Ferreira Sartori; Edmund Chada Baracat; Geraldo Rodrigues de Lima

    2002-01-01

    Objetivo: avaliar a ação dos estrogênios por via oral ou transdérmica nas células do trato urinário baixo e da vagina, em mulheres menopausadas. Métodos: foram incluídas 25 mulheres na pós-menopausa, nas quais se estudaram os efeitos citológicos da terapia de reposição hormonal estrogênica, por via oral e por via transdérmica, sobre as células da vagina e do sedimento urinário. As pacientes foram distribuídas aleatoriamente em 2 grupos: Grupo I, constituído por 14 mulheres que receberam 0,625...

  5. 益母草颗粒剂及血府逐瘀冲剂对减少药物流产后阴道出血的临床研究%Yimucao drop preparation and Xue fuzhuyu oral juice for reduction of vagina bleeding caused by medicine aborting

    王蕊; 胡燕琴

    2001-01-01

    目的:用中药治疗减少药物流产后阴道出血量及缩短阴道出血时间。方法:将150例病人随机分组,分别用益母草冲剂及血府逐瘀冲剂治疗流产后阴道出血。结果:单剂益母草颗粒剂及血府逐瘀冲剂对减少流产后阴道出血持续时间及出血量无临床差异,但二者合剂却能明显缩短出血时间及减少出血量。结论:复方合剂中药制剂对减少药物流产后阴道出血量及缩短出血时间有良好的临床效果。%Objective: medicine treatment for reducing vagina bleeding caused by medicine aborting. Method: 150 patients are at ranclom divided in to two groups given yimuco drop preparation and xuefuzhuyu oral juice to treat the vagina bleeing caused by medicine aborting, respectively. Results: There was no difference in reducing the lasting time and the amount of vagina bleeding caused by medicine aborting if either of the two drug alone was used. However, both of them used together showed better a treatment effect. Conclusion: The combination of the two chinese medicines has a very best clinice effect for reducing the lasting time and the amount of vagina bleeding after medicine aborting.

  6. Posterior Pelvic Exenteration and Plastic Operation of Vagina Constituted from the Sigmoid Flexure for Rectal Carcinoma Treatment in Female Patients%后盆脏器切除带蒂乙状结肠阴道修复术治疗女性直肠癌

    匡毅; 李福沛; 蒋又新; 赵和照

    2012-01-01

    Objective: This work aims to investigate the method and significance of postoperative restitution after pelvic exenteration on female rectal cancer patients. Methods: Since 1996, 49 cases of female rectal cancer underwent posterior pelvic exenteration in the Chongqing Cancer Institute. These patients received plastic operation of the vagina that was constituted from the sigmoid flexure. The pre-sacral space was simultaneously filled by the greater omentum. Primary suture of the perineum was performed in 34 out of 49 cases. Results: The reconstructed vaginas have a width of two fingers, a depth between 8 and 10 cm, and a smooth, soft, and lustrous quality. Their shape and localization were the same as those of the original vaginas, and the patients revealed they have satisfied sexual life and improved bladder function without dysuresia. Conclusion: mThe structural defect of the vagina was eliminated after posterior pelvic exenteration and plastic operation. The sexual function of the vagina was maintained, and the quality of life of the patients improved.%目的:探讨女性后盆腔脏器切除术后盆底结构重建的方法和意义.方法:1996年3月至2009年1月重庆市肿瘤研究所行女性后盆腔脏器切除术(posterior pelvic exenteration) 49例,其中采用移植带血管蒂乙状结肠作阴道成形,并以大网膜充填骶前间隙,一期缝合会阴切口34例.结果:再造阴道可容两指,长度8~9cm,壁光滑、柔软、润泽,形体位置与原阴道相近.患者性生活无障碍,膀胱功能良好,无排尿困难.结论:本术式弥补了直肠癌后盆切除术盆底结构缺损处理困难的缺陷,保留患者的性功能,提高了患者术后生存质量.

  7. 臭氧液阴道冲洗治疗假丝酵母菌病的疗效观察%Efficacy of douching vagina with ozone liquid in treatment of vulvovaginal candidiasis

    罗翠华; 陈晓燕; 李伟妙; 罗建华

    2014-01-01

    目的:观察单纯臭氧灭菌液配合改良阴道冲洗和臭氧液直接阴道内冲洗配合阴道给药两种不同方法的临床疗效,为进一步改进假丝酵母菌病的治疗方法提供依据。方法将2008年6月-2012年10月200例确诊外阴阴道假丝酵母菌病的患者随机分成两组,观察组100例采用单纯臭氧灭菌液配合改良阴道冲洗治疗,每天1次,疗程3 d;对照组100例采用臭氧液直接阴道内冲洗配合达克宁栓阴道给药,每天1次,疗程3 d ,每次冲洗前进行临床、真菌学疗效分析,比较两组的疗效及不良反应。结果治疗3 d后,观察组痊愈率达到91.0%,总有效率达98.0%;对照组痊愈率达57.0%,总有效率达81.0%;观察组症状缓解时间明显短于对照组,两组比较差异有统计学意义(P<0.05)。结论单纯臭氧灭菌液配合改良阴道冲洗治疗外阴阴道假丝酵母菌病疗效好,并且操作简单安全、不良反应少,患者容易接受,值得在临床中推广使用。%OBJECTIVE To observe the clinical curative effect of the treatment of vulvovaginal candidiasis by using pure ozone sterilizing liquid with modified vaginal douche compared with the method of douching the vagina with ozone liquid and vaginal drug delivery ,so as to providing evidence to modify the treatment of vulvovaginal candidi-asis further .METHODS Totally 200 cases of patients with vulvovaginal candidiasis in Jun 2008 to Oct 2012 were randomly divided into two groups .The 100 patients of observation group were treated with pure ozone sterilizing liquid with modified vaginal douche ,1 d ,period of treatment 3 d .The 100 patients of control group was treated by douching the vagina with ozone liquid directly and applying miconazole suppository ,1 d ,period of treatment 3 d .Each time the clinical and mycological efficacy were analyzed before treatment and the efficacy and adverse reac-tions were compared between

  8. 妊娠期外阴阴道假丝酵母菌病症状与妊娠结局分析%Vulva Vagina Candida Disease Symptoms During Pregnancy and Pregnancy Outcome Analysis

    莫培培

    2014-01-01

    目的:研究妊娠期外阴阴道假丝酵母菌病(VVC)症状与妊娠结局的关系。方法选取我院收集的136例妊娠>35 w患者阴道分泌物假丝酵母菌涂片阳性诊断VVC,其中有症状者60例作为观察组,无症状者76例作为对照组。观察两组妊娠结局及不良妊娠结局情况。结果观察组胎膜早破、产褥感染和剖宫产率与对照组比较差异有统计学意义(0.05)。结论妊娠期有症状VVC可致胎膜早破、剖宫产率等不良妊娠结局增高,早期诊断和治疗十分必要。%Objective To study the pregnancy vulva vagina candida disease symptoms and the relationship between pregnancy outcome (VVC). Methods Selected our hospital's col ection of 136 patients older than 35 weeks pregnancy vaginal candida smear positive diagnosis of VVC, including symptoms in 60 patients as observation group, asymptomatic 76 cases as control group. Observation two groups of pregnancy outcome and adverse pregnancy outcomes. Results The observation group of premature rupture of membranes, puerperal infection and cesarean section rate compared with control group dif erence was statistical y significant ( 0.05). Conclusion Symptomatic VVC during pregnancy can cause premature rupture of membranes, cesarean section rate increased and other adverse pregnancy outcomes, early diagnosis and treatment is necessary.

  9. Alanine transport across in vitro rabbit vagina.

    Hajjar, J J; Mroueh, A M

    1979-04-01

    Transmural flux of alanine across the vaginal epithelium of the rabbit is a specialized mechanism. There is a net serosal to mucosal translocation of the amino acid in the absence of a concentration gradient. Changes in reproductive cycle do not influence this mechanism but, in castrated animals, it is abolished. Transport properties of vaginal epithelium is important because of increasing utilization of intravaginal contraceptives. PMID:455986

  10. Sarcoidosis of the vagina treated with methotrexate.

    Şahin, N; Solak, A; Karaarslan, S; Doruk, S

    2016-06-01

    We describe the first case of mediolateral episiotomic sarcoidosis of the deep vaginal tissue, without involvement of the pulmonary parenchyma or pulmonary symptoms. A 68-year-old female was admitted with a vaginal mass that had developed about 1 month prior. On bimanual examination, we found a painful solid mass approximately 4 cm in diameter on the episiotomy line of the deep vaginal tissue. The patient underwent pelvic magnetic resonance imaging on suspicion of a malignancy, and a vaginal true-cut biopsy was performed. The biopsy specimen exhibited non-caseating, granulomatous inflammation and many multinucleated giant cells, strongly suggesting sarcoidosis. We had excluded other granulomatous diseases; a final diagnosis was made of stage-1 sarcoidosis in the deep vaginal mass. A 3-month course of methotrexate (2.5 mg/week) was commenced to treat a flare-up of rheumatoid arthritis. The vaginal mass resolved. To the best of our knowledge, this is the first case of sarcoidosis in a deep vaginal mass without pulmonary parenchymal or other solid-organ involvement. PMID:26624970

  11. Relationship of microecological environmental changes of vagina and two kinds of vaginitis%女性阴道微生态变化与两种阴道炎的关系

    杨岚; 邵兰芬; 陈道桢

    2011-01-01

    Objective To investigate the relationship of microecological environment of vagina and vulvovaginal candidiasis (VVC) and trichomonas vaginitis (TV) of women. Methods The examinations of hydrogen peroxide, sialidase and leukocyte esterase in vaginal secretions were performed with routine smear and BV triple test in 2380 cases with WC (group WC), 1399 cases with TV( group TV) and 648 healthy controls (group C). Results The positive rates of leukocyte esterase in groups of WC and TV were 34. 7% and 61. 5% .respectively,which were both higer than 6. 6% in group C(P<0. 05). The positive rate was higher in group TV than that in group VVC (P<0. 05). Conclusion The occurance of WC and TV is closely related to the unbanlance of vaginal microecological environment Examining vaginal secretions with routine smear and Bvset, especially with leukocyte esterase test,should be taken for guiding the microecological evaluation and controlling the recurrence of vaginitis.%目的 了解外阴阴道假丝酵母菌病(VVC)及滴虫性阴道炎(Tv)与阴道微生态情况的关系.方法 用常规检测和细菌性阴道病(BV)三联法(BVset)测定2380例WC(WC组)、1399例TV患者(TV组)和648例正常体检者(对照组)阴道分泌物中过氧化氢(H2O2)浓度、唾液酸苷酶和白细胞酯酶活性.结果 VVC和TV患者三联法检测白细胞酯酶阳性率分别为34.7%和61.5%,明显高于对照组的6.6%(P<0.05);且TV组的白细胞酯酶阳性率显著高于WC组(P<0.05).结论 VVC和TV的发生与阴道微生态环境的失衡密切相关;对患者进行白带常规检测的同时进行BVset尤其是白细胞酯酶活性测定,能更好地反映出患者阴道微生态状况,对控制阴道炎的复发有一定的指导意义.

  12. 心理干预对先天性无阴道患者术后婚姻和生活质量的影响%The influence on the quality of marital and life in the congenital absence of vagina patients with operation by psychological intervention

    张晓玲; 朱清仙

    2008-01-01

    目的 探讨心理干预对先天性无阴道患者术后婚姻和生活质量的影响.方法 将先天性无阴道患者按自愿原则分为干预组18例和非干预组11例,对干预组的患者进行术前的认知行为治疗,用Olson婚姻质量调查问卷及诺丁汉健康量表对两组手术前后生活质量以及术后婚姻质量进行评估.结果:干预组术后婚姻和生活质量评分均显著优于非干预组(P<0.05或P<0.01).结论 手术前心理干预能有效提高先天性无阴道患者术后婚姻和生活质量.%Objective To explore the influence on the quality of marital and life of the congenital absence of vagina patients with operation by psychological intervention.Methods The congenital absente of vagina patients were divided into psycholOgical intervened group(n=18,all cases were treated with the cognitive and behaviour therapy)and without intervened group(n=11).Before and after treatment the scores of the nottingham health poofity(NHP)were used in the two groups.After treatment the Olson's enrich questionary were tested also.Results The scores of NHP and Olson of psychological intervened group were significantly superior to those without intervened group(P<0.05 or P<0 01).Conclusion The cogntive and behaviour theraopy before operation is good for the quality of marital and life in congenital absence of vagina patients.

  13. 25%足叶草酯溶液外涂治疗85例阴道及宫颈尖锐湿疣的效果%Coating 25% Podophyllotoxin Liquid on the Vagina and Cervix Uteri Area for Treating the Verruca Acuminate:85 Case Reports

    张淑芳; 刘品娟; 陈海针

    2015-01-01

    Objective To develop an efifcient method for treating the verruca acuminate on the vagina and cervix uteri area. To analyze the safety and effectiveness of using the 25% podophyllotoxin on the vagina and cervix uteri area.Methods Dipping the 25% podophyllotoxin on the warts. Controlling the dose less than 0.5 mL. Dipping less and superifcially.Results The warts of Eighty-ifve patients were disappeared after the treatment. Five patients were found relapsing in a month. Given the same treatment once, the warts disappeared.Conclusion The method of using the 25% podophyllotoxin on the vagina and cervix uteri area for treating the verruca acuminate is a efifcient safe and non-invasive treatment.%目的:探讨治疗阴道及宫颈尖锐湿疣的有效方法,分析阴道和宫颈使用25%足叶草酯溶液治疗的安全有效性。方法点蘸25%足叶草酯溶液至疣体局部,每次用量控制在0.5 mL内,药液使用少而浅。结果85例患者在治疗后复诊皮损均消退,有5例在1个月后复查有复发,再予相同治疗使用一次后,皮损均消退。结论使用25%足叶草酯溶液外涂治疗阴道和宫颈尖锐湿疣,是一种有效,安全,无创的治疗方法。

  14. 保妇康栓联合乳酸菌阴道胶囊治疗妊娠期霉菌性阴道炎的临床效果%the Clinical Effect of Baofukang suppository Combined Lactobacillus Vagina Capsule Treatment Mould Sex Vaginitis During Pregnancy

    2013-01-01

      目的保妇康栓联合乳酸菌阴道胶囊治疗妊娠期霉菌性阴道炎的临床效果。方法将100例经临床确诊的霉菌性阴道炎患者随机分为观察组和对照组各50例,观察组给予保妇康栓联合乳酸菌阴道胶囊治疗,对照组给予保妇康治疗,比较两组患者的治疗效果。结果组治愈率为90%;对照组治愈率为74%,观察组显著高于对照组,两组比较,差异具有统计学意义(P<0.05)。结论保妇康与乳酸菌阴道胶囊联合治疗霉菌性阴道炎疗效确切,值得临床广泛应用。%Objective Baofukang suppository combined lactobacillus vagina capsule treatment, the clinical effect of mould sex vaginitis during pregnancy. Methods Will be 100 cases of clinically diagnosed with mould sex vaginitis were randomly divided into observation group and control group 50 cases each, observation group was given Baofukang suppository combined lactobacillus vagina capsule treatment, control group given bao fu kang treatment, compare the curative effect of two groups of patients. Results Group the cure rate is 90%; Control group cure rate was 74%, the observation group is significantly higher than the control group, two groups of comparisons, the difference was statistically significant (P<0.05). Conclusion Baofukang and lactobacillus vagina capsule combined treatment curative effect is mould sex vaginitis, worthy of clinical application widely.

  15. Colpoplasty by the Nympha Flap for the Treatment of Congenital Atresia of Inferior Vagina%小阴唇皮瓣法阴道成形术治疗阴道下段闭锁9例临床分析

    杨春燕; 吴晓芳

    2012-01-01

    目的 探讨小阴唇皮瓣法阴道成形术在治疗先天性阴道下段闭锁的临床效果.方法 回顾分析我院1994年1月-2011年11月收治的9例先天性阴道下段闭锁患者采用小阴唇皮瓣阴道成形术治疗的临床资料.结果 所有手术均获成功,所形成的阴道通畅,光滑湿润弹性好,所有病人月经正常,痛经缓解,性生活满意,有4例正常分娩.结论 小阴唇皮瓣法阴道成形术方法简便,效果好,是治疗先天性阴道下段闭锁良好的方法,值得临床推广应用.%Objective To explore the clinic effects of colpoplasty by the nympha flap for the treatment of congenital atresia of inferior vagina. Method The clinical data was retrospectively studied of 9 patients with congenital atresia of vagina treated by nympha flap colpoplasty. Results The follow-up results showed all the operations were successful without colpostenosis. The reconstructed vaginas were moist, elastic and smooth. The menstruation cycle was normal. The couples had satisfactory sex life and 4 cases achieved normal pregnancy and delivery. Conclusion It is recommended of the nympha flap colpoplasty for congenital gynatresia of simple operation and good efficacy.

  16. 保妇康栓联合乳酸菌阴道胶囊治疗妊娠期霉菌性阴道炎的临床效果%the Clinical Effect of Baofukang suppository Combined Lactobacillus Vagina Capsule Treatment Mould Sex Vaginitis During Pregnancy

    2013-01-01

    Objective Baofukang suppository combined lactobacillus vagina capsule treatment, the clinical effect of mould sex vaginitis during pregnancy. Methods Will be 100 cases of clinically diagnosed with mould sex vaginitis were randomly divided into observation group and control group 50 cases each, observation group was given Baofukang suppository combined lactobacillus vagina capsule treatment, control group given bao fu kang treatment, compare the curative effect of two groups of patients. Results Group the cure rate is 90%; Control group cure rate was 74%, the observation group is significantly higher than the control group, two groups of comparisons, the difference was statistically significant (P<0.05). Conclusion Baofukang and lactobacillus vagina capsule combined treatment curative effect is mould sex vaginitis, worthy of clinical application widely.%  目的保妇康栓联合乳酸菌阴道胶囊治疗妊娠期霉菌性阴道炎的临床效果。方法将100例经临床确诊的霉菌性阴道炎患者随机分为观察组和对照组各50例,观察组给予保妇康栓联合乳酸菌阴道胶囊治疗,对照组给予保妇康治疗,比较两组患者的治疗效果。结果组治愈率为90%;对照组治愈率为74%,观察组显著高于对照组,两组比较,差异具有统计学意义(P<0.05)。结论保妇康与乳酸菌阴道胶囊联合治疗霉菌性阴道炎疗效确切,值得临床广泛应用。

  17. The Application of Paries Anterior Vagina Muscularis Mucosal Flap in the Repairat/on of Female Complicated Urethrovaginal Fistula%阴道前壁肌黏膜瓣在女性复杂性尿道阴道瘘修补术中的应用

    罗道升; 米其武; 戴宇平; 邓春华

    2009-01-01

    Objective To explore the application of the paries anterior vagina U shape muscularis mucosal flap for the repairing of female complicated urethrovaginal fistula. Methods Fifteen complicated urethrovaginal fistulas patients resulted from severe pelvic frac-ture and with history of failing repairing urethrovaginal fistulas were analyzed retrospectively. The mean diameter of maximum urethrovagi-nal fistula was approximately 2.3 cm. The parias anterior vagina U shape mucosal flaps were used to repair the urethrovaginal fistulas, and the paries anterior vagina muscularis mucosae were used to cover the fistulas surface again. Results Fifteen patients were followed up for 6 to 80 months, and they gained normal voiding, with no urine leakage, urinary incontinence and urethra] stricture occurring. Conclusion The paries anterior vagina U shape mucosal flap is an effective technique for repairing complicated urethrovaginal fistula.%目的 探讨阴道前壁U形肌黏膜瓣修补复杂性尿道阴道瘘的应用价值.方法 分析复杂性尿道阴道瘘患者15例,均为车祸至严重骨盆骨折合并尿道阴道瘘,年龄18~56岁,平均31岁.病程2~16个月,平均7.5个月.瘘口大小1.1 cm×2.0 cm~1.5 cm ×2.5 cm,瘘口最大直径平均约2.3cm.有1次尿瘘修补手术史10例、有2次以上修补手术史5例.采用阴道前壁U形黏膜瓣翻转修补瘘口,阴道前壁肌黏膜层覆盖加固瘘口处创面.结果 15例患者术后随访6个月~80个月,均获正常排尿,无尿漏及尿失禁,无尿道狭窄.结论 阴道前壁U形黏膜瓣翻转术操作简单,成功率高,是一种修补复杂性尿道阴道瘘的有效方法 .

  18. 直肠黏膜环切术联合阴道后壁修补术和自拟通便方在治疗女性直肠前突型便秘的应用%The application of procedure for prolapse and hemorrhoids with vagina posterior wall repair and laxative in the treatment of female rectocele constipation

    宋健健; 辛学知; 许媛慧

    2016-01-01

    ObjectiveTo observe the clinical efficacies of procedure for prolapse and hemorrhoids with vagina posterior wall repair and laxative in the treatment of female rectocele constipation. Methods30 cases of female rectocele patients were treated with procedure for prolapse and hemorrhoids with vagina posterior wall repair and laxative. The effect and complications were observed.ResultsThe treatment effective rate was 96.67%, including 86.67% curative rate, the invalid rate was 3.33%. No postoperative infection, bleeding and rectovaginal fistula. Patients were followed up for 12 months to 18 months, All patients′symptoms were significantly alleviated except for one patient with defecation problems and feeling of anal pendant expansion.ConclusionsThe effect of prolapse and hemorrhoids with vagina posterior wall repair and laxative is significant, with low postoperative complications and recurrence rate, it was of worthy for promotion.%目的:观察女性直肠前突型便秘患者行直肠粘膜环切术(procedure for prolapse and hemorrhoids)+阴道后壁修补术(vagina posterior wall repair)联合自拟通便方治疗后的临床疗效。方法选取30例直肠前突女性患者,采用直肠粘膜环切术+阴道后壁修补术联合自拟通便方的方法治疗,观察此方法的有效率及术后并发症。结果此方法治疗的有效率为96.67%,其中痊愈率86.67%,无效率为3.33%。术后均未出现感染、出血及直肠阴道瘘等。术后随访12个月至18个月,除1例患者仍存在排便困难伴肛门坠胀感,余患者不适症状均有明显缓解。结论直肠粘膜环切术+阴道后壁修补术联合自拟通便方安全有效,效果显著,术后并发症及复发率低,值得推广。

  19. Laparoscopically sigmoid colon vaginoplasty in women with congenital absence of vagina: 11 cases report%全腹腔镜乙状结肠代阴道成形术治疗先天性无阴道11例临床分析

    涂春华; 蔡丽萍; 刘丝荪

    2011-01-01

    [Objectives] To evaluate the functional outcomes and technical feasibility of laparoscopically sigmoid colon vaginoplasty in women with congenital absence of vagina. [Methods] Clinical data of eleven women with congenital absence of vagina treated by laparoscopically sigmoid colon vaginoplasty were retrospectively analyzed. A record was made of operating time, bleeding volume, postoperative complications, anatomical and functional outcomes of artificial vagina. [Results] The mean operating time was 143.7 min and the mean bleeding volume was 123.7 mLr There were no significant postoperative complications and all women and their partners were satisfied with the subsequent sexual activity. [Conclusions] Laparoscopically sigmoid colon vaginoplasty is a feasible, safe and effective approach for women with congenital absence of vagina.%目的 分析全腹腔镜乙状结肠代阴道成形术的临床疗效,探讨其安全性及有效性.方法 回顾性分析11例运用全腹腔镜乙状结肠代阴道成形术治疗先天性无阴道患者的临床资料.观察11例全腹腔镜乙状结肠代阴道成形术的手术时间、出血量、术后并发症及人工阴道的解剖学、功能学结果.结果 11例全腹腔镜乙状结肠代阴道成形术均获得成功,平均手术时间143.7 min,平均出血量123.7 mL,新形成的阴道形态上接近正常阴道,患者性生活感觉满意,无术中及术后并发症发生.结论 全腹腔镜乙状结肠代阴道成形术是治疗先天性无阴道患者理想、安全且有效的阴道成形方法.

  20. Prevalência de cândida na flora vaginal de mulheres atendidas num serviço de planejamento familiar Prevalence of candida in the vagina of women attended at a family planning service

    Antônio Aleixo Neto

    1999-01-01

    Full Text Available RESUMO Objetivo: avaliar a prevalência de Candida sp. e a distribuição de suas espécies na flora vaginal de mulheres numa clínica de planejamento familiar. Método: estudo transversal no qual se avaliaram prospectivamente 72 mulheres não-grávidas, com ou sem queixas específicas, sendo coletadas amostras de secreção vaginal para cultura de leveduras, efetuada a medição do pH vaginal e anotados dados de achados do exame ginecológico. Resultados: leveduras pertencentes ao gênero Candida foram encontradas em 18 casos (25%. A C. albicans foi a espécie mais prevalente (77,8% e conseqüentemente 22,2% foram não-albicans. Entre as não-albicans a espécie mais prevalente foi a C. glabrata (16,7% seguida pela C. parapsilosis (5,6%. Prurido e ardor foram os únicos sintomas relacionados significativamente com a presença de cândida. Foi observado que a C. glabrata, ao contrário da C. albicans, não causa corrimento clinicamente verificável ao exame ginecológico. Não foram verificadas associações de alguns fatores predisponentes (idade, escolaridade e uso de contraceptivos com a presença ou não de cândida. Conclusões: nossos resultados sugerem: a uma alta prevalência de Candida sp. entre as mulheres (25%; b que as espécies não-albicans desempenham um papel importante no meio vaginal; c que prurido e ardor são os sintomas mais comuns na presença de cândida e d que a C. glabrata não costuma causar corrimento vaginal ao exame ginecológico. Finalmente, é importante observar que nossos resultados são consistentes com o que a literatura internacional tem mostrado nos últimos anos.SUMMARY Purpose: to estimate the prevalence of Candida sp. and the distribution of its species in the vagina of women attended at a family planning Service. Methods: a cross-sectional study evaluating prospectively 72 nonpregnant women, with or without specific complaints. Samples were checked for the presence of yeast and vaginal pH. Data obtained

  1. A randomized comparison of the laparoscopic peritoneal vaginoplasty and laparoscopic auxiliary sigmoid colon colpopoiesis techniques for congenital absence of vagina%腹腔镜腹膜代阴道成形术和乙状结肠代阴道成形术治疗先天性无阴道临床疗效比较

    曹莉莉; 徐惠成

    2012-01-01

    Objective To evaluate the therapeutic results of the laparoscopic peritoneal vaginoplasty and laparoscopic auxiliary sigmoid colon colpopoiesis procedures for congenital absence of vagina. Methods A single-center, random control study was carried out in 40 patients with congenital absence of vagina. According to random number table method, patients were randomized in 1 :2 ratio to received vaginal angioplasty, in which congenital absence of vagina under laparoscopic auxiliary sigmoid colon vaginoplasty 14 cases, laparoscopic peritoneal generation vaginal angioplasty 26 cases. Both surgical perioperative parameters and effects were investigated. Results All surgical procedures were successfully completed in laparoscopic surgery. Compared with the laparoscopic sigmoid vaginal replacement, laparoscopic vaginal reconstruction using peritoneum approach seems to be superior in perioperative parameters. The procedure is faster and less blood loss, postoperative course was uneventful and postoperative hospital stay days were lower than the laparoscopic-as-sisted sigmoid vagina (P 0.05). Conclusion For patients with congenital absence of vagina, the laparoscopic peritoneal vaginoplasty and the sigmoid colpopoiesis are safe, and reliable method for the correction of vaginal abnormalities. However, the laparoscopic peritoneal vaginoplasty is more invasive, retrieval time faster after surgery.%目的 探讨腹腔镜腹膜代阴道成形术和乙状结肠代阴道成形术的临床疗效.方法 采用随机对照的研究方法,对2001年1月至2010年12月第三军医大学附属西南医院40例先天性无阴道患者按随机表法,1:2随机化分组,分别接受腹腔镜乙状结肠代阴道成形术(14例)和腹膜代阴道成形术(26例),比较2组的围手术期参数及术后疗效.结果 40例患者均在腹腔镜下成功完成手术,腹膜代阴道组较乙状结肠代阴道组手术时间短,术中出血量少,术后恢复快(P<0.05).术后随访6~108个月,

  2. 凯妮汀联合定君生治疗妊娠期外阴阴道假丝酵母菌病的临床观察%Clinical Observation of Canesten Joint Born on Jun Treatment during Pregnancy Vulva Vagina Candida Disease

    陈娟

    2015-01-01

    Objective:To observe clinical effect of canesten clotrimazole vaginal tablet joint born on jun(vagina lactobacillus bacteria live capsule)treating vulva vagina candida disease during pregnancy(VVC). Method:60 cases of pregnancy VVC pregnant women were divided into research group and the control group. Control group was given routine treatment,canesten 1 piece of 0.5 g,deep into the vagina,use before bedtime,single drug used. Research group was given the conventional treatment,canesten 1 piece of 0.5 g,deep into the vagina,used before bedtime,single drug use. 4 days to give born on jun 1 grain of deep in the vagina,used before sleep every night,7 days in a row. The two groups before and after the treatment of vaginal cleanness,vaginal pH value and the cure rate were compared,the therapeutic effect was observed. Result:The vaginal cleannessⅠ-Ⅱdegrees accounted for 90.00%,the cure rate was 90.00%of research group after the treatment,cleanlinessⅠ-Ⅱdegrees accounted for 66.67%,the cure rate was 66.67%of control group.The vaginal pH value before and after treatment comparison difference was statistically significant(P<0.05). Conclusion:For pregnancy VVC,on the basis of antifungal therapy combined with lactobacillus preparation namely canesten joint born on jun can yet be regarded as a kind of curative effect of treatment,clinical popularization value.%目的:观察凯妮汀(克霉唑阴道片)联合定君生(阴道用乳杆菌活菌胶囊)治疗妊娠期外阴阴道假丝酵母菌病(VVC)的临床效果。方法:将60例妊娠期VVC的孕妇分为研究组及对照组。对照组按常规治疗,凯妮汀1片0.5 g,置于阴道深部,睡前使用,单次用药。研究组按常规治疗,凯妮汀1片0.5 g,置于阴道深部,睡前使用,单次用药;第4天再给予定君生1粒置于阴道深部,每晚睡前使用,连续7d。比较两组治疗前后的阴道清洁度、阴道pH值及治愈率,观察其治疗效

  3. Citologia Hormonal do Trato Urinário Baixo e da Vagina de Mulheres na Pós-menopausa, antes e durante Estrogenioterapia Oral e Transdérmica Urinary and Vaginal Cytology of Postmenopausal Women with Oral and Transdermal Estrogen Replacement

    Áurea Belas Lustosa

    2002-10-01

    Full Text Available Objetivo: avaliar a ação dos estrogênios por via oral ou transdérmica nas células do trato urinário baixo e da vagina, em mulheres menopausadas. Métodos: foram incluídas 25 mulheres na pós-menopausa, nas quais se estudaram os efeitos citológicos da terapia de reposição hormonal estrogênica, por via oral e por via transdérmica, sobre as células da vagina e do sedimento urinário. As pacientes foram distribuídas aleatoriamente em 2 grupos: Grupo I, constituído por 14 mulheres que receberam 0,625 mg de estrogênio conjugado eqüino associado a 5 mg de acetato de medroxiprogesterona, por via oral, diariamente sem intervalo por três meses, e Grupo II, formado por 11 mulheres que fizeram uso de 17-beta-estradiol matricial na dose de 50 mig, por via transdérmica, semanalmente, associado a 5 mg de acetato de medroxiprogesterona diariamente por três meses. As amostras urinárias foram obtidas do jato inicial da primeira urina da manhã, após asseio dos genitais, em frascos estéreis fornecidos pelo laboratório. A urina foi centrifugada e o esfregaço realizado a partir do sedimento urinário. Os esfregaços da vagina e do sedimento urinário foram imediatamente fixados em álcool absoluto e corados pelo método de Shorr. Resultados: observou-se que nas pacientes que utilizaram a via oral, houve maturação das células da vagina (o índice se elevou de 45,4 a 65,5 com dois meses de tratamento, permanecendo praticamente constante (62,0 a seguir. Quanto às células urinárias, não houve variação do valor de maturação (56,4 antes da medicação e 60,4 no final do período. Ao examinarmos tanto as células da urina quanto da vagina de pacientes que utilizaram a via transdérmica, notou-se que houve resposta satisfatória. Conclusão: com estes resultados podemos sugerir que os estrogênios, quando administrados por via transdérmica, estão associados à resposta satisfatória quanto ao trofismo tanto na vagina quanto na uretra

  4. 硝酸咪康唑栓与阴道冲洗联合治疗复发性外阴阴道假丝酵母感染的临床疗效%Clinical Curative Effect Analysis of Nitric Acid Health Thiazole Microphones and Vagina Washing Joint Bolt on the Treatment of Recurrent Vulvovaginal Candidiasis Candida Yeast Infection

    杨建庆; 张跃

    2013-01-01

    Objective: To study the health thiazole bolt and nitric acid microphones vagina washing joint on the treatment of recurrent vulvovaginal candidiasis candida mycoderma bacteria the treatment effect of the disease. Methods: 252 were our cases of recurrent vulvovaginal candidiasis candida mycoderma bacteria patients average divided into two groups, the observation group using nitric acid health thiazole microphones bolt joint vagina washing method treatment group using clotrimazole suppositories treatment, compared to two groups curative effect. Results: The observation group the cure rate of 91.3%; The control group cure rate was 57.9%. Significant difference (P< 0.05). Conclusion:Mi nitric acid health thiazole bolt and vagina washing joint on the treatment of recurrent vulvovaginal candidiasis candida mycoderma bacteria disease treatment effect is remarkable.%  目的:探讨硝酸咪康唑栓与阴道冲洗联合治疗复发性外阴阴道假丝酵母菌病的治疗效果。方法:将我院2009年3月~2012年6月期间收治的252例复发性外阴阴道假丝酵母菌病患者平均分为两组,对照组患者采用克霉唑栓剂治疗,观察组患者使用硝酸咪康唑栓与阴道冲洗法联合治疗,然后比较两组的临床疗效。结果:观察组的治愈率达91.3%;对照组的治愈率为57.9%。组间差异具有统计学意义(P<0.05)。结论:硝酸咪康唑栓与阴道冲洗联合治疗复发性外阴阴道假丝酵母菌病具有较高的临床疗效。

  5. From a Script to a Movement——Development Course of the Feminism Drama "The Vagina Monologue"%从剧本走向运动——论女性主义先锋剧《阴道独白》的发展历程

    石艺

    2012-01-01

    《阴道独白》不仅是一部女性主义先锋剧,更掀起了一场女性主义运动:作为一部剧本,其"独白"的特色鲜明;作为一种戏剧实践,它兼具先锋性与本土化的特征;作为一场戏剧运动,该戏取得的反响强烈、持久。%"The Vagina Monologues" is not only a feminist vanguard drama,but also set off a feminist movement.It has a distinctive characteristic of monologue as a drama itself and both vanguard and local features as a drama practice.It is also a peculiar drama movement gaining wide resonance and is of great enlightenment value.

  6. 广泛性子宫颈切除术加腹膜代阴道延长术治疗早期宫颈癌的临床研究%The clinical study of radical trachelectomy and vagina replacement by peritoneum in the treatment of early stage cervical cancer

    闫珺; 张菊新; 刘广芝; 王朕华

    2011-01-01

    Objective To compare the clinical results of radical trachelectomy and radical hysterectomy in treating patients with early stage cervical cancer and to evaluate the feasibility and security of radical trachelectomy and the sexual quality after vagina replacement by peritoneum. Methods Twenty-four women with early stage cervical cancer( IA2-IB1 ) were performed laparoscopic pelvic lymphadenectomy + radical trachelectomy + vagina replacement by peritoneum, and 32 women with early stage cervical cancer as control were performed laparoscopic pelvic lymphadenectomy + radical hysterectomy + vagina replacement by peritoneum. The operating time, blood lost, complications, recovery post surgery,recurrent rate and sexual quality were compared. For patients who received radical trachelectomy, the menstrual situation and pregnancy outcome post surgery were observed. Results All procedures were performed successfully. There was no significant difference between the two groups in the operating time, blood lost, complications, lymph node number or recovery post surgery ( P > 0. 05 ). Normal menstruation was recovered post surgery in all patients with radical trachelectomy. Pregnant rate was 45.45 % (5/11), full term delivery rate(Caesarean section) was 9.09% (1/11), miscarriage rate was 18.18% (2/11) ,and premature delivery rate was 18.18% (2/11). The two groups were followed up for 10 months to 5 years. There was no recurrent case and all patients were satisfied with their sexual activities. Conclusions Radical trachelectomy and radical hysterectomy have the same treating results for early stage cervical cancer. To prolong the vagina with peritoneum during the procedures can improve the sexual quality. Radical trachelectomy and vagina replacement by peritoneum is a selective treating strategy for patients with early stage cervical cancer who desire to preserve fertility and physiological function.%目的 比较广泛性子宫颈切除术与广泛性子宫切除术治疗早

  7. Local expression of surfactant protein A in the vagina of the patients with RVVC before and after treatment%表面活性蛋白A在复发性外阴阴道假丝酵母菌病患者治疗前后阴道局部的表达

    杨兰英; 贾俊茹; 王素芬; 李凤文

    2013-01-01

    Objective To observe the change of surfactant protein A(SP-A) level from the local vagina of the patients with recurrent vulvovaginal candidiasis (RVVC), discuss the relationship of the development and lapsing between SP-A and RVVC and analyze the effect of He-Ne laser (He -Ne) irradiation as the maintenance therapy on vaginal SP-A. Methods After initial antifungal treatment in the acute phase and adopting the maintenance therapy with He-Ne laser treatment for two courses for RWC patients (observation group), the treatment effect were followed up and the SP-A level of vaginal secretion were determined with ELISA method. At the same time, SP-A of the vaginal secretion specimen from healthy women of child-bearing age were detected and taken as control group. Results SP-A was (7. 24 ± 0. 76) nmol/L in control group with (1. 95 ± 0. 72) nmol/L in the acute phase of RVVC. After initial treatment, SP-A reached (2.92 ± 0. 53) nmol/ L, which was elevated comparing with that of acute episode (P<0.05). SP-A was (3. 64 ± 0. 62) nmol/L after the first treatment course with He-Ne laser, which got significant elevation comparing with that before laser treatment (P<0.05). After the second treatment course with laser, SP-A was (4.27 ±0.56) nmol/L, which was elevated comparing with that of the first treatment course (P< 0.05). On re-examination sixth months after stopping treatment, there was no significant difference for (3. 91 ± 0. 35) nmol/L of SP-A from local vagina in the observation group comparing with that of the laser treatment group after the second treatment course, but it was lower than that of the control group (P<0.001). There was significant decrease in SP-A from each group at various stages of RWC process comparing with that of the control group (P<0.001). Conclusion SP-A exists in local vagina, and the reduction of SP-A may be related to the development of RWC. The local irradiation with He-Ne laser may elevate SP-A level in vagina, thus, it provides evidence

  8. 保妇康凝胶联合乳酸菌素阴道胶囊治疗妊娠合并外阴阴道假丝酵母菌病的临床观察%Clinical Observation of Baofukang Gel Combined with Lactobacillus Vagina Capsule in Treatment of Pregnancy and Vulvovaginal Candidiasis

    田慧敏; 黄彦霞; 宋志红; 苏淑敏

    2013-01-01

    Objective:To explore the clinical curative effect and the safety of Baofukang gel combined with lactobacillus vagina capsule in treatment of vulvovaginal candidiasis. Method:Two hundred and seventy-two cases of pregnant women with vulvovaginal candidiasis were selected and randomly divided into two groups. Group A were given Baofukang gel combined with lactobacillus vagina capsule,while Group B were given only Baofukang gel. After using the medicines,the curative effect,drug’s side effect and recurrence rate between the two groups were compared. Result:The effective rate was 89.92%in group A while it was 76.22%in Group B after treatment,the total effective rate in Group A was significantly higher than that in Group B(P<0.05);The recurrence rate in Group A was 5%,while it was 19%in Group B,the difference was significant(P<0.01). Conclusion:The curative effect of Baofukang gel combined with lactobacillus vagina capsule in the treatment of vulvovaginal candidiasis is definite;It has little side effect and low recurrence rate.%目的:观察保妇康凝胶联合乳酸菌素阴道胶囊治疗妊娠合并外阴阴道假丝酵母菌病的临床疗效和安全性。方法:选择外阴阴道假丝酵母菌病的孕妇272例,随机分成两组。其中A组为保妇康凝胶联用乳酸菌素阴道胶囊组,用保妇康凝胶联合乳酸菌素阴道胶囊治疗, B组为保妇康凝胶组,单一应用保妇康凝胶治疗。用药后观察并比较两组治疗疗效、药物副作用及复发率情况。结果:治疗结束后,A组有效率89.92%,B组为76.22%,A组的总有效率明显高于B组,两组比较差异有统计学意义(P<0.05);复发率A组5%,B组19%,两者比较差异有统计学意义(P<0.01)。结论:保妇康凝胶联合乳酸菌素阴道胶囊治疗外阴阴道假丝酵母菌病疗效确切,副作用小,复发率低。

  9. Infectious characteristic analysis and drug-resistance of pathogens among vagina infection pregnancy with premature rup-ture of membranes%阴道病原菌感染与胎膜早破的关系及其耐药性分析

    楚丽娟; 罗婷婷; 杨桂林; 李秋红

    2014-01-01

    Objective The distribution characteristics and antibiotic resistance of specific pathogens among va-gina infection pregnancy with premature rupture of membranes (prom) ,in order to guide rational antibacterial thera-py .Methods During the periods of Jan ,2010 to Jul ,2012 ,pathogens from vagina with infectious pregnancy were gathered ,two groups-prom group and normal control were divided .The drug sensitivity of isolated strains were deter-mined by the broth dilution method .Results Only Streptococcus agalactiae (b group) and Staphylococcus aureus were found statistical significance between the two groups ,presenting higher detection in prom group(P<0 .05) .The resistant rates of Staphylococcus aureus to penicillin and ampicillin were 100% ,the sensitivity rates to erythrocin and azithromycin were 33 .3% and 50% ,respectively ,to tetracycline were 66 .7% ,others were all above of 83 .3% .The sensitivity rates of Streptococcus agalactiae (b group) to levofloxacin ,azithromycin ,erythrocin ,and ofloxacin were 30% ~40% ,yet above 80% of sensitivity to penicillin and cephems .Conclusion Streptococcus agalactiae (b group) and Staphylococcus aureus have an effect on prom .The drug sensitivity to the two bacteria are effected .Rational use of antibiotics and surveillance should be taken into account ,to avoid the development of drug-resistance strains .%目的:探讨影响孕妇胎膜早破的具体病原菌及其耐药情况,以合理地指导临床用药。方法随机选取2010年1月至2012年7月该院就诊的感染性胎膜早破的妊娠晚期女性为研究对象(患者组),未发生胎膜早破的孕妇作为对照(健康对照组),收集阴道分泌物病原菌,采用肉汤法进行药敏试验。结果患者组病原菌表现为无乳链球菌(b群)和金黄色葡萄球菌检出率高于健康对照组,差异有统计学意义( P<0.05)。金黄色葡萄球菌对氨苄西林和青霉素完全耐药,对红霉素和克

  10. Radiotherapeutic management of carcinomas of the vagina and vulva

    Purpose: To review important basic information regarding vaginal and vulvar carcinomas, including etiology, epidemiology, anatomy, pathology, spread patterns, presentation and work-up and staging. In addition, treatment concepts strategies, and radiotherapeutic techniques will be reviewed and discussed. Discussion: Vaginal carcinoma is rare, making up only 1-2% of gynecologic malignancies. However, the predominant role of radiotherapy (RT) is its management results in a significant number of patients referred to radiation oncology. Treatment and outcomes vary substantially according to stage. Important issues for consideration include the respective roles of external beam RT, brachytherapy, and surgery, intracavitary vs. interstitial brachytherapy, dose rate considerations, combined modality therapy, and management of non-squamous cell histologies. Vulvar carcinoma is similarly uncommon, comprising only 3-5% of gynecologic malignancies. Radiotherapy has a number of established roles in the management of this disease including adjuvant therapy, as part of combined modality treatment for advanced disease, salvage therapy, palliative treatment, and less often, as primary management. These issues will be discussed along with technical factors important in radiotherapeutic management. Finally, relevant literature will be reviewed with an emphasis of completed Gynecologic Oncology Group Trials

  11. Late effects of ionizing radiations on vulva, vagina and uterus

    Reporting and scoring complications after radiotherapy of gynaecological cancers is difficult because of the variety of treatment techniques involved. Use of an international classification is necessary to compare results obtained in series of patients treated in different institutions. An international group of experts designed in the early nineties the so-called French-Italian glossary. This classification of late effects is now completed with the new LENT SOMA scales. This paper contains details of these late changes, including their pathophysiology, clinical syndromes, potential treatment, and prevention. (authors)

  12. Biofilm formation among Candida albicans isolated from vagina

    2014-01-01

    Purpose: Study was conducted in a rural tertiary care hospital with a purpose to demonstrate the biofilm forming abilities of C. albicans isolated from cases of vulvovaginal candidiasis and asymptomatic carriers.Material and Methods: C. albicans was isolated and identified by standard laboratory techniques. Biofilm formation in vitro was tested using the 96 well microtitre plate method with crystal violet staining.Results: Overall rate of Candida isolation in study subjects was 40%. Candida i...

  13. Reconstruction of Acquired Defects of the Vagina and Perineum

    Salgado, Christopher J.; Chim, Harvey; Skowronski, Piotr P.; Oeltjen, John; Rodriguez, Meily; Mardini, Samir

    2011-01-01

    Successful reconstruction of vaginal and perineal defects requires close communication and cooperation between the extirpative and reconstructive surgeon. A variety of reconstructive options is available, dependent on the nature of the defect and extent of the ablative surgery. In all cases, obliteration of pelvic dead space and separation of intraabdominal contents from the perineum are important considerations to ensure uncomplicated perineal wound healing. The decision for vaginal reconstr...

  14. Pregnancy Complications: Bleeding and Spotting from the Vagina

    ... problem, but they can be a sign of miscarriage or other serious complications. Miscarriage is when a baby dies in the womb ... is a sign of a serious problem, like: Miscarriage . Almost all women who miscarry have bleeding or ...

  15. Laparoscopic management of fallopian tube prolapse masquerading as adenocarcinoma of the vagina in a hysterectomized woman

    Kucuk Mustafa

    2002-01-01

    Full Text Available Abstract Background Fallopian tube prolapse as a complication of abdominal hysterectomy is a rare occurrence. A case with fallopian tube prolapse was managed by a combined vaginal and laparoscopic approach and description of the operative technique is presented. Case presentation A 39-year-old woman with vaginal prolapse of the fallopian tube after total abdominal hysterectomy presented with an incorrect diagnosis of adenocarcinoma of the vaginal apex. The prolapsed tube and cystic ovary were removed by vaginal and laparoscopic approach. The postoperative course went well. Conclusions Early or late fallopian tube prolapse can occur after total abdominal hysterectomy and vaginal hysterectomy. Symptoms consist of persistent blood loss or leukorrhea, dyspareunia and chronic pelvic pain. Vaginal removal of prolapsed tube with laparoscopic surgery may be a suitable treatment. The abdominal or vaginal approach used in surgical correction of prolapsed tubes must be decided in each case according to the patient's individual characteristics.

  16. Radiotherapy for carcinoma of the vagina. Immunocytochemical and cytofluorometric analysis of prognostic factors

    Blecharz, P. [Maria Sklodowska-Curie Memorial Institute, Krakow (Poland). Dept. of Gynecological Oncology; Reinfuss, M.; Jakubowicz, J. [Maria Sklodowska-Curie Memorial Institute, Krakow (Poland). Dept. of Radiation Oncology; Rys, J. [Maria Sklodowska-Curie Memorial Institute, Krakow (Poland). Dept. of Tumor Pathology Oncology; Skotnicki, P.; Wysocki, W. [Maria Sklodowska-Curie Memorial Institute, Krakow (Poland). Dept. of Oncological Surgery

    2013-05-15

    Background and purpose: The aim of this study was to assess the potential prognostic factors in patients with primary invasive vaginal carcinoma (PIVC) treated with radical irradiation. Patients and methods: The analysis was performed on 77 patients with PIVC treated between 1985 and 2005 in the Maria Sklodowska-Curie Memorial Institute of Oncology, Cancer Center in Krakow. A total of 36 patients (46.8 %) survived 5 years with no evidence of disease (NED). The following groups of factors were assessed for potential prognostic value: population-based (age), clinical (Karnofsky Performance Score [KPS], hemoglobin level, primary location of the vaginal lesion, macroscopic type, length of the involved vaginal wall, FIGO stage), microscopic (microscopic type, grade, mitotic index, presence of atypical mitoses, lymphatic vessels invasion, lymphocytes/plasmocytes infiltration, focal necrosis, VAIN-3), immunohistochemical (protein p53 expression, MIB-1 index), cytofluorometric (ploidity, index DI, S-phase fraction, proliferation index SG2M) factors. Results: Significantly better 5-year NED was observed in patients: < 60 years, KPS {<=} 80, FIGO stage I and II, grade G1-2, MIB-1 index < 70, S-phase fraction < 10, and proliferation index < 25. Independent factors for better prognosis in the multivariate Cox analysis were age < 60 years, FIGO stage I or II, and MIB-1 index < 70. Conclusion: Independent prognostic factors in the radically irradiated PIVC patients were as follows: age, FIGO stage, MIB-1 index. (orig.)

  17. First report of transvaginal endoscopic microsurgery in a patient with squamous cell carcinoma of the vagina

    Smink, M.; Hermans, R.H.; Schoot, D.B.; Luyer, M.; Pijnenborg, J.M.A.

    2013-01-01

    Transanal endoscopic microsurgery has been used by surgeons since 1983. All these years of experience and research have shown that this is a safe and successful approach for rectal neoplasms, both benign and malignant. The advantage of this procedure is the excellent view and hence precise surgical

  18. Uterine perforation with bowel prolapsing through vagina following an unsafe abortion

    Kamala Verma; Girish Chandra Baniya

    2016-01-01

    An unwanted pregnancy may lead to induced abortion that means willful termination of pregnancy before the period of viability. Most of the times when termination of pregnancy is done by skilled person in fully aseptic environment, complications are low. But severe complication including uterine perforation, bowel injury, sepsis and sometimes death is common when the procedure is carried out by unskilled personnel in unhealthy condition. This case representing the neglected scenario of our mat...

  19. Uterus didelphys with an obstructed unilateral vagina and ipsilateral renal agenesis: A rare cause of dysmenorrhoea

    ATTAR, Rukset; Yıldırım, Gazi; Inan, Yücel; Küzılkale, Özge; Karateke, Ateş

    2013-01-01

    Didelphic uterus with obstructed hemivagina and ipsilateral renal agenesis is a rare condition. It usually presents with pelvic pain following the menarche, dysmenorrhoea, and an increase in abdominal volume or a palpable mass due to unilateral haematocolpos. We present the case of a 13-year-old girl who referred with recurrent pelvic pain, mainly at the time of menses, and irregular menstrual cycle complaints in this report. The patient underwent ultrasonography and magnetic resonance (MR) i...

  20. Primary invasive cancer of the vagina: outcome and complications of therapy

    The aim of the present study was to review the characteristics of cases of vaginal cancer, results of treatment and complications occurring at Westmead Hospital over the period 1979-96. International Federation of Gynaecology and Obstetrics (FIGO) staging and Eastern Cooperative Oncology Group (ECOG) status had been recorded prospectively, while other information was obtained retrospectively, including complications using the Franco-Italian Glossary. There were 37 eligible patients, 34 of whom were treated radically. Five-year survival for stage I was 90%, for stage 11 it was 50%, and for stage III it was 40%. There was only one stage-V patient. The majority of patients who relapsed did so locally (63%). Using the Franco-Italian Glossary 10.8% of patients had, at worst, G0 toxicity, 21.6% had G1 toxicity, 29.7% had G2 toxicity, 37.8% had G3 toxicity, and no patients had G4 toxicity. Seven patients (18.9%) had a laparotomy for a complication of therapy. Excluding the three palliative patients and controlling for disease stage, it was found that there was a trend to improved survival in patients who had brachytherapy and those who suffered worse complications. While results for treatment of early stage vaginal cancer appear good, new techniques, particularly those that improve local control, are required for higher stage disease. Copyright (1999) Blackwell Science Pty Ltd

  1. Primary T-Cell Non-Hodgkin Lymphoma of the Vagina

    Herraiz, J. L.; Llueca, A.; Maazouzi, Y.; Piquer, D.; A. Palmeiro; Calpe, E.

    2015-01-01

    The primary vaginal T-cell non-Hodgkin lymphoma is a rare form of lymphoma. Most of the previously published cases were about B-cell non-Hodgkin lymphomas. We present the case of a vaginal mass in an 82-year-old patient presenting vaginal bleeding. The results of the immunohistological studies of the mass revealed the presence of a cytotoxic T-cell non-Hodgkin lymphoma, which is the least common subtype.

  2. Sheila Jeffreys: The Industrial Vagina. The Political Economy of the Global Sex Trade. London: Routledge 2008.

    Susanne Hofmann

    2010-03-01

    Full Text Available Sheila Jeffreys analysiert die Prozesse, die zu einer Industrialisierung und Globalisierung von Prostitution im späten 20. und 21. Jahrhundert geführt haben. Hauptverantwortlich für die gegenwärtige Diskursverschiebung um Prostitution ist für Jeffreys zum einen die sexuelle Revolution der 1970er Jahre und zum anderen die massive Finanzierung von Unterstützer/-innen der Sexarbeiterinnen zur HIV-Prävention in den 1980ern. Jeffreys legt wie in früheren Arbeiten ihre radikal-feministische Position dar und fordert eine Abschaffung der Prostitution. In ihrer Abrechnung mit dem liberalen feministischen Diskurs, für den eine Unterstützung von Sexarbeiterinnen prioritär ist, ignoriert sie die Widersprüchlichkeiten und Komplexitäten der gelebten Realitäten. An vielen Stellen ihres Buches bekräftigt Jeffreys stereotypische Männlichkeitsvorstellungen, was durch einen Blick über den Tellerrand des ihr vertrauten wissenschaftlichen Bezugsrahmens hätte vermieden werden können.Sheila Jeffreys analyzes the processes that led to the industrialization and globalization of prostitution in the late 20th and 21th centuries. Jeffreys considers those primary factors responsible for the current shift in discourse on prostitution, which can be attributed to the sexual revolution of the 1970s on the one hand, and to massive financing of HIV prevention in the 1980s by sex worker supporters on the other. As in earlier studies, Jeffreys presents readers with her radical-feminist position and demands prostitution be abolished. In her confrontation with liberal-feminist discourse, in which the support of sex workers takes priority, she ignores the inconsistencies and complexities of real lived experience. At many points throughout her book, Jeffreys affirms stereotypical male conceptions, which could have been avoided had she looked beyond the theoretical frame of reference that makes up her comfort zone.

  3. Fine structure of the male reproductive ducts, vagina and seminal receptacle of Cyathocephalus truncatus (Cestoda: Spathebothriidea)

    Poddubnaya, L. G.; Mackiewicz, J. S.; Bruňanská, Magdaléna; dezfuli, B. S.

    2005-01-01

    Roč. 52, č. 3 (2005), s. 241-250. ISSN 0015-5683 R&D Projects: GA ČR GA206/03/1317 Grant ostatní: Russian Foundation of Fundamental Research(RU) 05-0448250 Institutional research plan: CEZ:AV0Z60220518 Keywords : ultrastructure * reproductive organs * Cestoda Subject RIV: EA - Cell Biology Impact factor: 1.138, year: 2005

  4. Clinical Holistic Medicine: Holistic Sexology and Acupressure Through the Vagina (Hippocratic Pelvic Massage)

    Søren Ventegodt; Birgitte Clausen; Hatim A. Omar; Joav Merrick

    2006-01-01

    Many gynecological and sexological problems (like urine incontinence, chronic pelvic pains, vulvodynia, and lack of lust, excitement, and orgasm) are resistant to standard medical treatment. In our work at the Research Clinic for Holistic Medicine in Copenhagen, we have found that vaginal acupressure, or Hippocratic pelvic massage, can help some of these problems. Technically, it is a very simple procedure as it corresponds to the explorative phase of the standard pelvic examination, suppleme...

  5. Uterus didelphys with an obstructed unilateral vagina and ipsilateral renal agenesis: A rare cause of dysmenorrhoea.

    Attar, Rukset; Yıldırım, Gazi; Inan, Yücel; Küzılkale, Ozge; Karateke, Ateş

    2013-01-01

    Didelphic uterus with obstructed hemivagina and ipsilateral renal agenesis is a rare condition. It usually presents with pelvic pain following the menarche, dysmenorrhoea, and an increase in abdominal volume or a palpable mass due to unilateral haematocolpos. We present the case of a 13-year-old girl who referred with recurrent pelvic pain, mainly at the time of menses, and irregular menstrual cycle complaints in this report. The patient underwent ultrasonography and magnetic resonance (MR) imaging of the pelvis was performed. The diagnosis was uterus didelphys with obstructed hemivagina and ipsilateral renal agenesia. Laparotomy was performed for diagnosis and treatment purposes. Two separated hemiuteri and two cervices with hematometra and hematocolpos on the right side and ipsilateral renal agenesis were detected. The vaginal septum was excised completely and Strassman metroplasty was performed. Her complaints were resolved and she was absolutely asymptomatic after surgery. Diagnosis and management of this congenital anomaly is challenging due to the complexity of the anatomic structures, nonspecific complaints, and heterogenic presentation. These anomalies must always be considered while working-up female patients presenting with episodic abdominal pain and abdominopelvic mass. PMID:24592115

  6. Surgical instrument migration from the abdominal cavity through the bladder into the vagina: a rare long-term complication.

    Gier, R.P.E. de; Feitz, W.F.J.

    2002-01-01

    A foreign body in the bladder is a well-recognized, although rare, cause of urinary tract infections. We describe a 15-year-old girl who presented with abdominal pain and recurrent urinary tract infections. On analysis, a forceps was found, with the two legs of the instrument separately perforating

  7. Pelvic Organ Prolapse in Fibulin-5 Knockout Mice : Pregnancy-Induced Changes in Elastic Fiber Homeostasis in Mouse Vagina

    Peter G. Drewes; Yanagisawa, Hiromi; Starcher, Barry; Hornstra, Ian; Csiszar, Katalin; Marinis, Spyridon I.; Keller, Patrick; Word, R. Ann

    2007-01-01

    Pelvic organ prolapse is strongly associated with a history of vaginal delivery. The mechanisms by which pregnancy and parturition lead to failure of pelvic organ support, however, are not known. Recently, it was reported that mice with null mutations in lysyl oxidase-like 1 (LOXL1) develop pelvic organ prolapse. Elastin is a substrate for lysyl oxidase (LOX) and LOXL1, and LOXL1 interacts with fibulin-5 (FBLN5). Therefore, to clarify the potential role of elastic fiber assembly in the pathog...

  8. From toothpick legs to dropping vaginas: Gender and sexuality in Joan Rivers' stand-up comedy performance

    Lockyer, S.

    2011-01-01

    This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2011 Intellect. This article employs sociocultural analysis to examine Joan Rivers’ stand-up comedy performances in order to reveal how she successfully operates in a sphere of artistic expression that has been, and continues to be, male-dominated. The analysis uncovers how Rivers’ stand-up comedy performance involves a complex combination of elements and how it fuses feature...

  9. Sodium Tetradecyl Sulphate Direct Intralesional Sclerotherapy of Venous Malformations of the Vulva and Vagina: Report of Five Cases

    We report five cases of female patients affected by symptomatic focal external genital venous malformations treated with percutaneous direct intralesional injection of sodium tetradecyl sulphate (STS). All patients were referred because of discomfort and pain when sexual intercourse was attempted. Direct sclerotherapy with 3% STS was performed on a day-hospital basis with the patient under local anesthesia. Complete resolution of the symptoms was achieved in all cases. No major adverse effects were reported. Direct intralesional sclerotherapy with STS may be considered a safe and effective method for the treatment of female external genital malformation without the necessity of general anesthesia for pain control.

  10. SU-E-T-579: Impact of Cylinder Size in High-Dose Rate Brachytherapy (HDRBT) for Primary Cancer in the Vagina

    Zhang, H; Gopalakrishnan, M; Lee, P; Sathiaseelan, V [Department of Radiation Oncology, Northwestern Memorial Hospital, Chicago, IL (United States)

    2014-06-01

    Purpose: To evaluate the dosimetric impact of cylinder size in high dose rate Brachytherapy for primary vaginal cancers. Methods: Patients treated with HDR vaginal vault radiation in a list of cylinders ranging from 2.5 to 4 cm in diameter at 0.5 cm increment were analyzed. All patients’ doses were prescribed at the 0.5 cm from the vaginal surface with different treatment lengths. A series of reference points were created to optimize the dose distribution. The fraction dose was 5.5 Gy, the treatment was repeated for 4 times in two weeks. A cylinder volume was contoured in each case according to the prescribed treatment length, and then expanded to 5 mm to get a volume Cylinder-5mm-exp. A volume of PTV-Eval was obtained by subtracting the cylinder volume from the Cylinder-5mm-exp. The shell volume, PTV-Eval serves as the target volume for dosimetric evaluation. Results: DVH curves and average doses of PTV-Eval were obtained. Our results indicated that the DVH curves shifted toward higher dose side when larger cylinder was used instead of smaller ones. When 3.0 cm cylinder was used instead of 2.5 cm, for 3.0 cm treatment length, the average dose only increased 1%, from 790 to 799 cGy. However, the average doses for 3.5 and 4 cm cylinders respectively are 932 and 1137 cGy at the same treatment length. For 5.0 cm treatment length, the average dose is 741 cGy for 2.5 cm cylinder, and 859 cGy for 3 cm cylinder. Conclusion: Our data analysis suggests that for the vaginal intracavitary HDRBT, the average dose is at least 35% larger than the prescribed dose in the studied cases; the size of the cylinder will impact the dose delivered to the target volume. The cylinder with bigger diameter tends to deliver larger average dose to the PTV-Eval.

  11. Treatment of patients with a congenital transversal vaginal septum or a partial aplasia of the vagina. The vaginal pull-through versus the push-through technique.

    Bijsterveldt, C.D. van; Willemsen, W.N.P.

    2009-01-01

    STUDY OBJECTIVE: The aim of this study is to describe the different modalities of congenital obstructing vaginal malformations and the evaluation of techniques to solve the problem. DESIGN: A retrospective study. SETTING: The University Hospital Nijmegen, the Netherlands. PARTICIPANTS: The medical r

  12. Squamous cell carcinoma of the penis and of the cervix, vulva and vagina in spouses: is there any relationship? An epidemiological study from Norway, 1960-92.

    T. Iversen; Tretli, S.; A. Johansen; Holte, T.

    1997-01-01

    Four hundred and twenty-three wives of 671 men with cancer of the penis were compared with 444 wives of 569 men who did not have this disease. The risk among the wives of patients with cancer of the penis of preinvasive and invasive cancer of the neck of the uterus was 1.75 (95% CI 0.42-7.37).

  13. Late effects of ionizing radiations on vulva, vagina and uterus; Effets tardifs des radiations ionisantes sur la vulve, le vagin et l`uterus

    Mazeron, J.J. [Groupe Hospitalier Pitie-Salpetriere, 75 - Paris (France); Gerbaulet, A. [Institut Gustave Roussy, 94 - Villejuif (France)

    1997-12-01

    Reporting and scoring complications after radiotherapy of gynaecological cancers is difficult because of the variety of treatment techniques involved. Use of an international classification is necessary to compare results obtained in series of patients treated in different institutions. An international group of experts designed in the early nineties the so-called French-Italian glossary. This classification of late effects is now completed with the new LENT SOMA scales. This paper contains details of these late changes, including their pathophysiology, clinical syndromes, potential treatment, and prevention. (authors)

  14. Nonoxynol-9 berberine plural gel has little effect on expression of SLPI, SP-D and lactoferrin in mice’s vagina

    Huang Guangying; Chen Suhua; Lu Fuer; Ma Yonggui; Qiao Yuan; Chen Zhuo

    2013-01-01

    Background: The most frequently used spermicide Nonoxynol-9 (N-9) in the clinic alters the vaginal flora, which will result in an increased risk of opportunistic infection. So development of a novel spermicidal and microbicidal drug appears to be inevitable. Vaginal local immune is an important part of vaginal flora. Secretory leukocyte protease inhibitor (SLPI), surfactant proteins D (SP-D), and lactoferrin (LF) are anti-microbial molecules with important roles in immune system of female vag...

  15. SU-E-T-579: Impact of Cylinder Size in High-Dose Rate Brachytherapy (HDRBT) for Primary Cancer in the Vagina

    Purpose: To evaluate the dosimetric impact of cylinder size in high dose rate Brachytherapy for primary vaginal cancers. Methods: Patients treated with HDR vaginal vault radiation in a list of cylinders ranging from 2.5 to 4 cm in diameter at 0.5 cm increment were analyzed. All patients’ doses were prescribed at the 0.5 cm from the vaginal surface with different treatment lengths. A series of reference points were created to optimize the dose distribution. The fraction dose was 5.5 Gy, the treatment was repeated for 4 times in two weeks. A cylinder volume was contoured in each case according to the prescribed treatment length, and then expanded to 5 mm to get a volume Cylinder-5mm-exp. A volume of PTV-Eval was obtained by subtracting the cylinder volume from the Cylinder-5mm-exp. The shell volume, PTV-Eval serves as the target volume for dosimetric evaluation. Results: DVH curves and average doses of PTV-Eval were obtained. Our results indicated that the DVH curves shifted toward higher dose side when larger cylinder was used instead of smaller ones. When 3.0 cm cylinder was used instead of 2.5 cm, for 3.0 cm treatment length, the average dose only increased 1%, from 790 to 799 cGy. However, the average doses for 3.5 and 4 cm cylinders respectively are 932 and 1137 cGy at the same treatment length. For 5.0 cm treatment length, the average dose is 741 cGy for 2.5 cm cylinder, and 859 cGy for 3 cm cylinder. Conclusion: Our data analysis suggests that for the vaginal intracavitary HDRBT, the average dose is at least 35% larger than the prescribed dose in the studied cases; the size of the cylinder will impact the dose delivered to the target volume. The cylinder with bigger diameter tends to deliver larger average dose to the PTV-Eval

  16. Characterization of cytological changes, IgA, IgG and IL-8 levels and pH value in the vagina of prepubertal and sexually mature Ellegaard Göttingen minipigs during an estrous cycle

    Lorenzen, Emma; Agerholm, Jørgen Steen; Grossi, Anette Blak;

    2016-01-01

    The pig is increasingly used as an advanced animal model of the genital tract in women and knowledge on the genital immune system is therefore needed.In this study, evaluation of vaginal smears revealed that almost no neutrophils or other leukocytes were present in the vaginal mucosa of prepubert...

  17. Perioperative Nursing for Elderly Patients with Severe Pelvic Organ Prolapse Treated with Vagina Closure Surgery%重度盆腔器官脱垂患者行阴道封闭术的围术期护理

    冯莹; 张燕; 陈丽

    2010-01-01

    @@ 盆腔器官脱垂(pelvic organ prolapse,POP)是中老年妇女的常见病,发病率约为40%[1].POP患者,特别是POP-QⅢ期(依据国际尿控协会制定的盆腔器官脱垂定量分度法[2])及以上者,常合并有排尿和排便困难、尿失禁及粪失禁等症状,严重影响其日常生活.

  18. Characterization of cytological changes, IgA, IgG and IL-8 levels and pH value in the vagina of prepubertal and sexually mature Ellegaard Göttingen minipigs during an estrous cycle.

    Lorenzen, Emma; Agerholm, Jørgen Steen; Grossi, Anette Blak; Bojesen, Anders Miki; Skytte, Christina; Erneholm, Karin; Follmann, Frank; Jungersen, Gregers

    2016-06-01

    The pig is increasingly used as an advanced animal model of the genital tract in women and knowledge on the genital immune system is therefore needed. In this study, evaluation of vaginal smears revealed that almost no neutrophils or other leukocytes were present in the vaginal mucosa of prepubertal minipigs (n = 10). In sexually mature minipigs (n = 10), evaluated through an estrous cycle, there was an increase in number of mucosal neutrophils and other leukocytes during estrus. The level of total IgA on the vaginal mucosa increased during diestrus. The level of total IgG showed no significant changes through the cycle. The vaginal IgA level in the prepubertal minipigs was similar to the low estrus level in sexually mature minipigs, and the IgG level in prepubertal was similar to the stable level in the sexually mature minipigs. PMID:26801101

  19. 外阴阴道假丝酵母菌性阴道病阴道局部固有免疫机制研究%Study on inherent immunity in vagina infected with vulvovaginal candidiasis

    彭丹红; 任慕兰

    2009-01-01

    目的 探讨外阴阴道假丝酵母菌性阴道病(VVC)阴道局部固有免疫机制.方法 选取2006年1月至2008年3月健康体检妇女、单纯性VVC患者和复发性VVC(RVVC)患者各20例,采集阴道灌洗液,行HE染色,细胞计数及分类,采用RT-PCR法测定阴道脱落细胞中单核细胞趋化蛋白-1(MCP-1)的mRNA水平.结果 (1)VVC组和RVVC组灌洗液的pH值分别为5.035±0.63和5.430±0.66,与对照组4.572±0.27比较,差异有统计学意义(P<0.05).(2)细胞分类中,VVC组中性粒细胞[(46.45±7.61)%]与对照组和RVVC组[分别为(18.25±3.27)%和(17.7±4.30)%]比较,差异有统计学意义(P<0.01);VVC组单核细胞(5.40±2.30)%,较对照组(3.90±1.68)%和RVVC组(3.70±1.42)%明显上升,差异有统计学意义(P<0.01).(3)对照组、VVC组和RVVC组MCP-1的mRNA表达分别为0.6363±0.0300、0.8338±0.1100、0.5315±0.0600,VVC组MCP-1的mR-NA显著高于对照人群,而RVVC组MCP-1的mRNA显著低于对照人群.结论 (1)阴道pH的改变与阴道的感染相关.(2)假丝酵母菌侵入机体后将导致机体的免疫防御反应,中性粒细胞和单核细胞数量增加并到达炎症部位发挥杀灭病原菌的作用.(3)阴道局部MCP-1低表达相关的免疫防御缺陷可能是RVVC反复发作的机制之一.

  20. 扩张阴道联合改良会阴保护法在接产中的临床应用%Expansion the vagina joint improvement perineum protection of clinical applications in the confinements

    易翠兰

    2013-01-01

      目的探讨扩张阴道联合改良会阴保护法在接产中的应用效果。方法选择2012年1月~12月在我科分娩的300例初产妇,随机分为观察组168例和对照组132例。观察组在接产过程中采用扩张阴道联合改良会阴保护法保护会阴;对照组采用传统式保护会阴法。并比较两组会阴裂伤及产后出血情况。结果观察组会阴裂伤88例,占52.38%,对照组会阴裂伤101例,占76.52%,两组比较有显著性差异(P<0.01);两组会阴裂伤程度、产后出血情况比较有显著性差异(P<0.01)。结论在接产过程中采用扩张阴道联合改良会阴保护法保护会阴,可降低会阴裂伤发生率,减轻会阴裂伤程度,保持会阴完整性,,以减轻产妇的痛苦。同时也减少产后出血的发生。%Objective In the production process through vaginal dilation and improved protection of perineum protection of perineum ,in order to reduce perineal laceration and side of the cutting rate ,reduce maternal pain ,and to observe its effect .Methods 300 cases of our hospital in 2012 were the single fetal head position of women in the 1-12 months ,weeks of gestation 37 ~ 41 weeks ,age 19-35 years old ,vaginal ,no lateral episiotomy indications of maternal .Were randomly di-vided into the observation group and 168 cases of vaginal dilation ,through improved protection of perineum protection of perineum inproduction process ;132 cases in the control group ,the traditional protection of perineum .Results in the obser-vation group ,88 cases of perineal laceration accounted for 52 .38% ,control group ,101 cases of perineal laceration accounted for 76 .52% ,the difference was statistically significant (P<0 .01);the two group of perineal laceration degree ,postpartum hemorrhage compared the differences were statistically significant (P<0 .01) .Conclusion In the production process through vaginal dilation and improved protection of perineum protection of perineum ,can reduce the incidence rate of perineal lacera-tion ,alleviate perineal laceration of perineum ,maintain integrity ,to reduce maternal pain .At the same time ,reduce the inci-dence of postpartum hemorrhage .

  1. 温度敏感性壬苯醇醚阴道用缓释凝胶的制备与评价%Preparation of temperature-sensitive nonoxynol-9 sustained-release gel for vagina

    王成伟; 唐星; 王晓梅; 田晓琳; 李真

    2006-01-01

    目的:制备以聚丙烯酸类为基本材料的温度敏感性壬苯醇醚阴道用缓释凝胶,建立温度敏感性阴道用缓释凝胶剂的体内外评价方法.方法:采用均匀试验设计,考察了泊洛沙姆F127和F68对凝胶化温度及25℃时和37℃时的黏度变化的影响,筛选出优化组合;加入聚丙烯酸类材料制备凝胶,进行显微观察、释放度、灌流冲洗量、黏度与黏附力评价;大鼠阴道内给予优化处方与国外产品,测定阴道冲洗液中药物的质量浓度.结果:温度敏感性材料优化组合为:泊洛沙姆F127的质量分数为18.2%,泊洛沙姆F68的质量分数为8.8%,制备的凝胶在大鼠阴道滞留时间可达12 h以上,室温下有较好的流动性.结论:温度敏感性壬苯醇醚阴道用缓释凝胶具有良好的体外释放性能、温度敏感黏附性能及阴道内滞留性能.

  2. Preparation and in vitro drug release characterization of nonoxynol-9 sustained-release gel for vagina%壬苯醇醚阴道用缓释凝胶的研制

    王成伟; 唐星; 姚家荣

    2004-01-01

    目的制备壬苯醇醚阴道用缓释凝胶并优化其处方与工艺.方法采用正交试验设计,考察了聚卡波菲用量、卡波沫用量、pH值、甘油用量、液体石蜡用量、山嵛酸甘油酯用量及不同工艺对释放度的影响,与国外产品进行残差平方和、拟合度、区分因子和相似因子比较,确定壬苯醇醚阴道用缓释凝胶的处方工艺,并考察了其初步稳定性.结果优化所得处方工艺为:聚卡波菲用量0.5%(w),卡波沫用量1%(w),甘油用量为5%(w),液体石蜡用量为5%(w),山嵛酸甘油酯用量为1%(w),pH值为4.5,选用工艺1.结论按优化处方工艺制得的壬苯醇醚阴道用缓释凝胶稳定,与国外产品比较具有相似的释放度,且以复合模式释放.

  3. 自慰、阴道-阴茎性行为、无性生活与快乐模型%Pleasure model of self-consolation,vagina -penis sexual behavior and celibacy

    田聚群

    2014-01-01

    According to the properties of skeletal muscle,frequency of sexual behavior can be divided into 4 types:injury frequency,dependence frequency,free frequency and zero frequency.To analyze from the perspec-tive of sexual desire disappearance,persons of dependence frequency,free frequency and zero frequency have the same living conditions.The person that has sexual intercourse and no sexual intercourse is of the same living condi-tions.Analyzing from the perspective of skeletal muscle dependence and pleasure model,self-consolation and va-gina-penis sexual behavior are in parallel relation.%根据骨骼肌的性质,性行为频率可以划分为4种类型:损伤频率;依赖频率;自由频率;零频率。从产生的性行为渴望完全消失的角度分析,选择依赖频率、自由频率和零频率的人拥有同样的生存状态,选择有性生活和无性生活的人拥有同样的生存状态。从骨骼肌依赖性质和快乐模型的角度分析,自慰和阴道-阴茎性行为是并列关系。

  4. Uterine prolapse

    ... include: Pressure or heaviness in the pelvis or vagina Problems with sexual intercourse Leaking urine or sudden ... cervix drops into the lower part of the vagina . Uterine prolapse is moderate when the cervix drops ...

  5. Condoms - male

    ... contained in a male's semen reach a woman's vagina, pregnancy may occur. Condoms work by preventing sperm ... coming in contact with the inside of the vagina. If condoms are used correctly every time intercourse ...

  6. Estradiol Topical

    ... a medication that is applied topically to the vagina. Estradiol is in a class of medications called ... swelling, redness, burning, irritation, or itching of the vagina vaginal discharge Some side effects can be serious. ...

  7. Terconazole Vaginal Cream, Vaginal Suppositories

    ... to treat fungal and yeast infections of the vagina.This medication is sometimes prescribed for other uses; ... a cream and suppository to insert into the vagina. It is usually used daily at bedtime for ...

  8. Butoconazole Vaginal Cream

    ... is used to treat yeast infections of the vagina.This medication is sometimes prescribed for other uses; ... comes as a cream to insert into the vagina. It is usually used daily at bedtime. Follow ...

  9. Nystatin

    ... to treat fungal infections of the skin, mouth, vagina, and intestinal tract. Fungal medicines will not work ... and vaginal cream to be inserted into the vagina; and in powder, ointment, and cream to be ...

  10. Urinary incontinence - tension-free vaginal tape

    ... small surgical cut (incision) is made inside your vagina. Two small cuts are made in your belly ... tape is passed through the cut inside the vagina. The tape is then positioned under your urethra. ...

  11. Clotrimazole

    ... is used to treat yeast infections of the vagina, mouth, and skin such as athlete's foot, jock ... and vaginal cream to be inserted into the vagina. Clotrimazole is usually used five times a day ...

  12. Bacterial vaginosis - aftercare

    ... BV) is a type of vaginal infection. The vagina normally contains both healthy bacteria and unhealthy bacteria. ... when you urinate Itching inside and outside the vagina You also may not have any symptoms.

  13. What Is Vaginal Cancer?

    ... of the uterus) to open up at the vulva (the external female genitals). The vagina is lined ... cancer. Likewise, if the cancer involves both the vulva and the vagina, it’s considered a vulvar cancer. ...

  14. Medications for Pain Relief during Labor and Delivery

    ... that carry feeling to the vagina , vulva , and perineum . The drugs are given just before delivery. They ... spine. Episiotomy: A surgical incision made into the perineum (the region between the vagina and the anus) ...

  15. Healthy Sexuality

    Full Text Available ... from the walls of the vagina. The vaginal muscles relax, causing the vagina to lengthen and widen. ... causing it to rise and stiffen. The smooth muscles of the scrotum contract, the skin of the ...

  16. Vaginitis

    ... led to advances in knowledge about the normal microflora of the vagina, reproductive behavior of yeast, and ... association between certain lactobacilli species in the normal microflora in the vagina and protection from bacterial vaginosis ( ...

  17. Condom

    ... work by keeping semen (the fluid that contains sperm) from entering the vagina. The male condom is ... off when he gets soft. If this happens, sperm could enter the vagina. Female Condom The female ...

  18. Ethinyl Estradiol and Etonogestrel Vaginal Ring

    ... as a flexible ring to place in the vagina.It is usually placed in the vagina and left in place for 3 weeks. After ... the contraceptive ring a certain way inside your vagina. The ring will work no matter how it ...

  19. Comparative study vagina mould/ fletcher applicator in MRI guided pulsed rate brachytherapy in patients reached by an uterine cervix carcinoma; Etude comparative moule vaginal/applicateur de fletcher en curietherapie de debit pulse guide par IRM chez les patientes atteintes d'un cancer du col uterin

    Francois, G.; Dumas, I.; Mazeron, R.; Verezesan, O.; Monnier, L.; Vieillot, S.; Gensse, M.C.; Haie-Meder, C. [Institut Gustave-Roussy, 94 - Villejuif (France)

    2009-10-15

    This study began in february 2009 and included until today ten patients. twenty patients are planned. The analysis of preliminary results show a much higher tolerance for the vaginal cast device. The dosimetry data were the object of a preliminary study that seems demonstrate an equivalence of the both modalities, with differences concerning the doses to critical organs; The definitive result swill be presented with the data including the twenty planned patients. (N.C.)

  20. Onamot Kang zuo union bacillus lacticus live fungus preparation treatment retinitis simplex vulva vagina rayon saccharomycetes sickness curative effect analysis%咪康唑联合乳酸杆菌活菌制剂治疗单纯性外阴阴道假丝酵母菌病疗效分析

    李莉; 杨东霞

    2010-01-01

    目的:观察咪康唑,定君生联合用药治疗单纯性外阴阴道假丝酵母菌病(vulvovaginal candidiasis,VVC)的疗效.方法:将门诊150名VVC患者随机分为二组(n=75)A组阴道上达克灵400mg三天评定疗效,B组阴道上达克灵400mg三天同时阴道上定君生十天评定疗效.结果:A、B两组10天后治愈率分别为67%、69%.B组治愈率略高于A组(P>0.05),一月后复发率A、B两组分别是16%、5.77%,差异显著(P<0.05).结论:咪康唑合并乳酸杆菌胶囊治疗能降低VVC复发率.

  1. Cervical occlusion in women with cervical insufficiency: protocol for a randomised, controlled trial with cerclage, with and without cervical occlusion

    Secher, Niels Jørgen; MaCormack, CD; Weber, Tom;

    2007-01-01

    , without the membranes being exposed to the vagina. 6. Tertiary cerclage: Short cervix, membranes exposed to the vagina. Observational study: Eligible women who refuse to be randomised will participate in an observational study. 7. Repeat/requested cervical occlusion. METHODS: The women will be randomised...

  2. Formation of a vesicovaginal fistula in a pig model

    Lindberg, Jennifer; Rickardsson, Emilie; Andersen, Margrethe;

    2015-01-01

    the bladder and the vagina was made, and the mucosa between them was sutured together with absorbable sutures. A durometer ureteral stent was introduced into the fistula, secured with sutures to the bladder wall, allowing for the formation of a persistent fistula tract. Six weeks postoperatively cysto...... be an effective and cheap way to create a fistula between the bladder and vagina....

  3. Initiation and progression of Müllerian duct derived malignancies

    P.H. van der Horst (Paul)

    2013-01-01

    textabstractThe female reproductive system consists of the internal and external genitalia. The external genitalia are formed by the vulva, which includes the clitoris, labia majora and minora, urethral orifice and vestibule of the vagina (lower part of the vagina). The internal genital system is lo

  4. HERLYN - WERNER - WUNDERLICH SYNDROME (HWW SYNDROME): A CASE REPORT

    Pallavi S.; Ganpat; Gaurav

    2015-01-01

    Congenital anomalies of the mullerian duct system can result in various urogenital anomalies and, Herlyn Werner Wunderlich syndrome (HWW syndrome) is one such rare anomaly . This syndrome is characterized by uterus didelphys with blind hemi vagina and ipsilateral renal agenesis . 1 it is also known as OHVIRA (Obstructed Hemi vagina with ...

  5. Apical blebs on sperm-storage tubule epithelial cell microvilli: their release and interaction with resident sperm in the turkey hen oviduct

    Technical Abstract: Located at the anterior end of the turkey hen vagina are numerous discrete tubular invaginations of the surface epithelium, collectively referred to as the sperm-storage tubules (SSTs). Following mating or artificial insemination, sperm ascend the vagina, enter the SSTs, and ove...

  6. SEMEN COLLECTION AND CONSERVATION OF BULLS SEMEN PODOL TYPE CATTLE

    Premzl, B.; Božić, P.; Viduč, D.; Dejanović, Dubravka; Geceg, I.

    1994-01-01

    Semen collection, artificial vagina, electro-ejaculation, freeze semen We tray to collection ejaculates from bulls Podol Type Cattle with artificial vagina. Fantoms for collecting were cows in heat from the same herd or from another herd. We were not successafuly. With electro-ejaculation we collected ejaculates from bulls Podol Type Cattle and freeze semen in our Institute or in field.

  7. Surgical Tutorial of a Robotic-Assisted Anterior Pelvic Exenteration

    Full Text Available ... United States to have recurrence of her cervical cancer in the anterior portion of the cervix and the anterior vagina and it invading into ... involving the posterior bladder, the vagina and the cervix completely ... negative for cancer. She was surgically cured with this procedure that ...

  8. Microflora of urogenital tract in pregnancy with asymptomatic bacterium

    The article contains results of research interrelationship from colonization of vagina and urinary tract diseases. E.coli one of the main factors in development asymptomatic bacterium. Presented high effects of penicillin medicaments and nitrofurans in treatment of asymptomatic bacterium

  9. General Ultrasound Imaging

    Full Text Available ... major branches liver gallbladder spleen pancreas kidneys bladder uterus , ovaries , and unborn child ( fetus ) in pregnant patients ... inserted into a woman's vagina to view the uterus and ovaries. top of page What will I ...

  10. Hysteroscopy

    ... the uterus . A hysteroscope is a thin, lighted telescope-like device. It is inserted through your vagina ... hysteroscope, bleeding may occur, or excess fluid may build up in your system. In rare cases, hysteroscopy ...

  11. Postpartum Vaginal Stenosis Due to Chemical Vaginitis.

    Kaur, Gurcharan; Sinha, Maruti; Gupta, Ridhima

    2016-05-01

    Acquired vaginal stenosis is a rare obstructing anomaly, which can be caused by use of chemicals in the vagina. A 21-year-old gravida 1 para 1, presented with secondary amenorrhea and inability to have sexual intercourse, after normal spontaneous vaginal delivery complicated by post partum bleeding. The delivery was conducted by untrained traditional birth attendant at home. The wash cloth soaked with caustic soda was packed in the patient's vagina and was left in situ for 10 days, which ultimately led to the severe scarring and stenosis of the vagina. Patient underwent surgical management and the extensive vaginal adhesions were excised and a patent vagina was reconstructed. Patient then reported successful vaginal intercourse without dyspareunia. Post partum vaginal stenosis due to chemical vaginitis is rare. These cases can be prevented by adequate training of untrained health care workers. PMID:27437311

  12. Perforated transverse vaginal septum: a rare case report

    Ramaraj Sasikala

    2015-08-01

    Full Text Available 20 year old nulliparous woman married since 1 and frac12; years attended the gynaecology OPD with history of inability to conceive. She had regular menstrual cycles with normal menstrual flow. Local examination revealed blind vagina with a small opening in the centre. On per rectal examination, uterus was felt and normal in size. Based on history and clinical examination finding, a provisional diagnosis of perforated transverse vaginal septum was made. MRI revealed transverse vaginal septum in the lower 1/3rd of vagina with a small fenestration without haematocolpos or haematometra. Transverse vaginal septum resection was done. Vagina healed well without stricture formation. Transverse vaginal septum in the lower 1/3rd of vagina (perforating type is a rare entity and hence it is presented. [Int J Reprod Contracept Obstet Gynecol 2015; 4(4.000: 1217-1219

  13. DHEA

    ... HIV sometimes take DHEA by mouth to ease depression and fatigue. Women sometimes use DHEA inside the vagina for strengthening ... months improves the appearance of skin in postmenopausal women. Depression. Most research shows that taking 30-500 mg ...

  14. What is a Urogynecologist?

    ... About "It" Talking About PFD 3 Resources + More Pelvic Organ Prolapse POP Symptoms & Types Can I Prevent POP? POP ... by a urogynecologist include urinary incontinence or leakage, pelvic organ prolapse (dropping of the vagina, uterus, cystocele, rectocele), and ...

  15. Clindamycin Vaginal

    Vaginal clindamycin is used to treat bacterial vaginosis (an infection caused by an overgrowth of harmful bacteria in the vagina). Clindamycin is in a class of medications called lincomycin antibiotics. It works by slowing or stopping ...

  16. Medroxyprogesterone Injection

    ... have ever had any other bone disease or anorexia nervosa (an eating disorder); or if you drink ... of the vagina white vaginal discharge changes in sexual desire cold or flu symptoms pain, irritation, lumps, ...

  17. Ovarian Cancer Stage II

    ... primary peritoneal cancer) shows cancer in the pelvic peritoneum. Also shown are the cervix and vagina. In ... peritoneal cancer, cancer is found in the pelvic peritoneum and has not spread there from another part ...

  18. Episiotomy - aftercare

    Perineal laceration - aftercare; Vaginal birth perineal tear - aftercare; Postpartum care - episiotomy - aftercare ... to widen the opening of the vagina. A perineal tear or laceration often forms on its own ...

  19. Genital warts

    ... genitals. They may be found on the penis , vulva , urethra, vagina , cervix , and around and in the ... HPV can cause cancer of the cervix and vulva. They are the main cause of cervical cancer. ...

  20. Lymphogranuloma venereum

    ... lymph nodes in the groin Swelling of the vulva or labia in women Swollen lymph nodes in ... Infections of the lower and upper genital tracts: vulva, vagina, cervix, toxic shock syndrome, endometritis, and salpingitis. ...

  1. Rectocele

    ... isolated finding or occur as part of a generalized weakening of the pelvic floor muscles. Other pelvic ... to defecate on a specially-designed commode after contrast material is instilled in the rectum, vagina and ...

  2. Surgical Tutorial of a Robotic-Assisted Anterior Pelvic Exenteration

    Full Text Available ... part of the vagina, the cervix and surrounding tissues as well last the uterus and both tubes ... sac. We see some radiation fibrosis, the mottled tissue from fibrosis. And that will become an issue ...

  3. Women and HIV

    ... on HIV testing. Gynecological problems can be early signs of HIV infection . Ulcers in the vagina, persistent yeast infections, and severe pelvic inflammatory disease (PID) can be signs of HIV. Hormone changes, birth control pills, or antibiotics can ...

  4. Sexual abuse in children - what to know

    Sexual abuse - children ... boys are sexually abused before they turn 18. Sexual abuse of children is any activity that the abuser ... anus or vagina Tongue kissing Oral sex Intercourse Sexual abuse can also happen without physical contact, such as: ...

  5. Sexual Problems

    Full Text Available ... pleasurable sexual sensations in her clitoris or vagina. Male erectile disorder, or ED, is the inability of ... physical, psychological, medical conditions, or medications. Men with male orgasmic disorder have a delay in, or absence ...

  6. Colposcopy

    ... in the stirrups as you would for a Pap smear. Your doctor inserts a speculum into your vagina ... your doctor find the reason for an abnormal Pap smear. Why is colposcopy important? A colposcopy is important ...

  7. Sexual Problems

    Full Text Available ... occur with entry into the vagina or as deep pain. Both psychological and physical factors can contribute ... All Rights Reserved. ASRM Non Discrimination Policy | ASRM Web Site Terms & Conditions of Use | Web Design and ...

  8. Biopsy - polyps

    Polyp biopsy ... are treated is the colon. How a polyp biopsy is done depends on the location: Colonoscopy or flexible sigmoidoscopy explores the large bowel Colposcopy-directed biopsy examines the vagina and cervix Esophagogastroduodenoscopy (EGD) or ...

  9. Surgical Tutorial of a Robotic-Assisted Anterior Pelvic Exenteration

    Full Text Available ... In this procedure, I remember us gathering about 42 lymph nodes in total. Yes. And urologists who ... the vagina and the cervix completely removed, all 42 lymph nodes were negative for cancer. She was ...

  10. Urine 24-hour volume

    ... test results: Dehydration Any type of x-ray exam with dye (contrast material) within 3 days before the urine test Fluid from the vagina that gets into the urine Emotional stress Heavy exercise Urinary tract infection

  11. 24-hour urine protein

    ... of fluid (dehydration) Any type of x-ray exam with dye (contrast material) within 3 days before the urine test Fluid from the vagina that gets into the urine Severe emotional stress Strenuous exercise Urinary tract infection

  12. Dyspareunia: Painful Sex for Women

    ... part of the genitals can cause pain during sex. Some conditions affect the skin around the vagina. ... types of birth control) does not fit correctly, sex may also be painful. Vaginismus (say: "vag-in- ...

  13. Ultrasound -- Pelvis

    Full Text Available ... and processes the sounds and creates graphs or color pictures that represent the flow of blood through ... into the vagina. The images are obtained from different orientations to get the best views of the ...

  14. Vaginal Yeast Infection

    ... Centers for Diseases Control and Prevention. Micrograph showing Candida albicans from a patient with vaginal candidiasis, also known ... caused by an overgrowth of a fungus called Candida albicans in the vagina. Candida is yeast, which is ...

  15. Paroxetine

    ... amount of serotonin, a natural substance in the brain that helps maintain mental balance. There is not ... itching, burning, or infection in the vagina painful erection that lasts for hours sudden nausea, vomiting, weakness, ...

  16. Intraperitoneal leech: A rare complication of leech bite

    Manoj Saha; Sedengulie Nagi

    2011-01-01

    An intraperitoneal leech, which entered through vagina and uterus in a 2-year-old girl is reported. The child presented with intraperitoneal hemorrhage and shock. A leech inside the peritoneal cavity has never been reported in the literature.

  17. Stages of Uterine Sarcoma

    ... uterus. The uterus is part of the female reproductive system . The uterus is the hollow, pear-shaped organ ... to the vagina . Enlarge Anatomy of the female reproductive system. The organs in the female reproductive system include ...

  18. Birth Control: Medicines to Help You

    ... STIs)? No. Sponge with Spermicide Spermicides containing N9 (nonoxynol-9) can irritate the vagina and rectum. It ... polyurethane sponge-like device with the spermicide N9 (nonoxynol-9) in it. How do I use it? ...

  19. Cancer treatment: fertility and sexual side effects in women

    ... tissue is removed. Chemotherapy can cause: Loss of sexual desire Pain with sex and problems having an orgasm ... with fertility Radiation therapy can cause: Loss of sexual desire Changes in the lining of your vagina, which. ...

  20. Pelvic Floor Dysfunction

    ... of the vagina. Smaller rectoceles may only be obvious when the woman strains. Video defecography can be ... exact cause is not known, but anxiety and depression have been closely associated with levator syndrome. HOW ...

  1. Vaginal yeast infection

    Yeast infection - vagina; Vaginal candidiasis; Monilial vaginitis ... Most women have a vaginal yeast infection at some time. Candida albicans is a common type of fungus. It is often found in small amounts in the ...

  2. Sonohysterography

    ... the vagina. The images are obtained from different orientations to get the best views of the uterus ... can be important when establishing a treatment or management strategy for a patient's particular condition. Following the ...

  3. Surgical Tutorial of a Robotic-Assisted Anterior Pelvic Exenteration

    Full Text Available ... for locally invasive cervical cancer. She did very well, had no evidence of her cancer, as I ... the vagina, the cervix and surrounding tissues as well last the uterus and both tubes and ovaries. ...

  4. Menstruation and Menstrual Problems

    ... the egg moves down the fallopian tube. The sperm can fertilize the egg at this point. Fertilization ... called conception (pronounced kuhn-SEP-shuhn ). After the sperm is ejaculated into the vagina, it moves into ...

  5. Birth control and family planning

    ... vagina over the cervix before intercourse, to prevent sperm from reaching the uterus. It should be left ... and contain a chemical that kills or "disables "sperm. The sponge is moistened and inserted into the ...

  6. Abnormal Uterine Bleeding (Beyond the Basics)

    ... of breast cancer, tamoxifen use or a family history of breast cancer or colon cancer. (See "Patient information: Endometrial cancer diagnosis and staging (Beyond the Basics)" .) During the biopsy, a thin instrument is inserted through the vagina ...

  7. Surgical Tutorial of a Robotic-Assisted Anterior Pelvic Exenteration

    Full Text Available ... to you by Intuitive Surgical. During the program, it’s easy for you to learn about the procedure. ... of the cervix and the anterior vagina and it invading into the posterior bladder. To make matters ...

  8. Sexual Problems

    Full Text Available ... may be due to many factors, including physical, psychological, medical conditions, or medications. Men with male orgasmic ... into the vagina or as deep pain. Both psychological and physical factors can contribute to the condition. ...

  9. Infertility and Women

    ... these drugs. Sometimes doctors use drug treatment with intrauterine insemination (IUI), when sperm are released into the uterus through ... a thin flexible tube) inserted through the vagina. IUI is done at the time of ovulation. Other ...

  10. Stroke Fact Sheet

    ... tells you to. Return to top Does taking birth control pills increase my risk for stroke? Taking birth ... your vagina Return to top Does using the birth control patch increase my risk for stroke? The patch ...

  11. Glycoproteins of mouse vaginal epithelium: differential expression related to estrous cyclicity

    Horvat, B; Multhaupt, H A; Damjanov, I

    1993-01-01

    in proestrus, coincident with the transformation of two superficial layers of vaginal squamous epithelium into mucinous cuboidal cells. Electron microscopic lectin histochemistry revealed the glycoproteins in the mucinous granules of surface cuboidal cells and in the lumen of the vagina. Our results illustrate...... the complexity of glycoconjugate synthesis in mouse vagina and reveal the distinct cycle-specific patterns of individual glycoprotein expression. These cyclic glycoproteins could serve as vaginal biochemical markers for the specific phases of the estrous cycle....

  12. Magnetic resonance imaging of vaginal and vulval pathology

    Griffin, N.; Grant, L.A.; Sala, E. [Addenbrooke' s Hospital, Department of Radiology, Box 219, Cambridge (United Kingdom)

    2008-06-15

    There are a number of conditions affecting the vagina and vulva that can be optimally assessed with the use of high-resolution magnetic resonance imaging (MRI). This paper gives a suggested protocol for MRI technique and sequences for imaging the pelvis and perineum and reviews the MRI appearances of many of the common pathologies affecting the vagina and vulva. Congenital anomalies, inflammatory and neoplastic entities such as vaginal and vulval carcinoma are discussed, with rarer malignancies also reviewed. (orig.)

  13. Herlyn Werner Wunderlich Syndrome with Hematocolpos: An Unusual Case Report of Full Diagnostic Approach and Treatment

    Rohit Bhoil; Ajay Ahluwalia; Narvir Chauhan

    2016-01-01

    Herlyn-Werner-Wunderlich (HWW) syndrome is an uncommon combined müllerian duct anomalies (MDAs) and mesonephric duct malformation of female urogenital tract characterized by uterus didelphys and obstructed hemi-vagina and ipsilateral renal agenesis (OHVIRA) syndrome. We present a rare and unusual case of this syndrome in a 19 year-old female who suffered from hypomenorrhoea and abdominal pain. She had an obstructed hemi-vagina on right side which led to marked distention of ...

  14. HPV type infection in different anogenital sites among HIV-positive Brazilian women

    Donadi Eduardo Antonio; Franceschi Silvia; Burattini Marcelo N.; Villa Luisa L; Arslan Annie; Randi Giorgia; Gonçalves Maria; Massad Eduardo

    2008-01-01

    Abstract Objectives To evaluate the prevalence of human papillomavirus (HPV) types, and risk factors for HPV positivity across cervix, vagina and anus, we conducted a study among 138 women with human immunodeficiency virus (HIV). Goal Compare the prevalence of different HPV types and the risk factors for HPV positivity in three sites. Results The most frequently detected HPV types in all sites were, in decreasing order, HPV16, 53, 18, 61 and 81. Agreement between the cervix and vagina was goo...

  15. Rare association in a female DSD case of phallus, accessory phallic urethra, perineal lipoma and anterior ectopic anus.

    Mahalik, Santosh Kumar; Mahajan, Jai Kumar; Sodhi, Kushaljit Singh; Garge, Saurabh; Vaiphei, Kim; Rao, Kattragadda L

    2013-02-01

    Disorders of sex differentiation (DSD) are a heterogeneous and broad spectrum group of diseases with a varied appearance. Presence of an accessory phallus with a phallic urethra in association with a normal vagina in a female is an extremely uncommon anomaly. We present a rare case of a genotypically female child with a normal urethra and vagina in association with a phallus, accessory phallic urethra, perineal lipoma and anterior ectopic anus. PMID:22836203

  16. Community and research staff collaboration for development of materials to inform microbicide study participants in Africa

    Cynthia Woodsong; John Michael Mutsambi; Smangalisa Ntshele; Peggy Modikoe

    2014-01-01

    Introduction: Clinical trials of new vaginal products require careful communication with participants about trial requirements. Most microbicide trials have been multi-site studies conducted among women in sub-Saharan Africa, where literacy levels and understanding of scientific methods differ from those designing and conducting the trials. Microbicide trials require women to insert objects in their vagina and ensure they are present in the vagina during sex. For many women, this is a novel b...

  17. Magnetic resonance imaging of vaginal and vulval pathology

    There are a number of conditions affecting the vagina and vulva that can be optimally assessed with the use of high-resolution magnetic resonance imaging (MRI). This paper gives a suggested protocol for MRI technique and sequences for imaging the pelvis and perineum and reviews the MRI appearances of many of the common pathologies affecting the vagina and vulva. Congenital anomalies, inflammatory and neoplastic entities such as vaginal and vulval carcinoma are discussed, with rarer malignancies also reviewed. (orig.)

  18. Vulvovaginitis in prepubertal girls

    Stricker, T; Navratil, F; Sennhauser, F

    2003-01-01

    This retrospective study evaluated the clinical features and findings in bacterial cultures and in microscopic examination of vaginal secretions in 80 prepubertal girls, aged 2–12 years, with vulvovaginitis. Vaginal secretions were obtained directly from the vagina with a sterile catheter carefully inserted into the vagina. Pathogenic bacteria were isolated in 36% of cases. In 59% of these cases the isolated pathogen was group A ß-haemolytic streptococcus. Candida was not found in any of the ...

  19. Scientific Rationale and Algorithmization of Sochi Resort Natural and Preformed Physical Therapeutic Factors in the Course of Combined Treatment of Patients with Chronic Vulvovaginitis

    Kirill V. Gordon; Evgenii F. Filippov; Svetlana M. Avtomeenko

    2012-01-01

    Chronic vulvovaginitis is the most wide-spread gynecological pathology among women of childbearing age. The chief causations of nonspecific vulvovaginitis are reduction in oestrogen, disturbances in vaginal acidity, intestine dysbacteriosis, local and general immune disturbances. The growth of vagina opportunistic pathogenic flora is closely connected with the increase of bacterial slimes on vagina mucus. Sulphur balneotherapy in the form of general baths and vaginal irrigations, mechanical p...

  20. Infection through structured polymicrobial Gardnerella biofilms (StPM-GB)

    Swidsinski, Alexander; Loening-Baucke, Vera; Mendling, Werner; Dörffel, Yvonne; Schilling, Johannes; Halwani, Zaher; Jiang, Xue-Feng; Verstraelen, Hans; Swidsinski, Sonja

    2014-01-01

    BACKGROUND: We analysed data on bacterial vaginosis (BV) contradicting the paradigm of mono-infection. METHODOLOGY: Tissues and epithelial cells of vagina, uterus, fallopian tubes and perianal region were investigated using fluorescence in situ hybridization (FISH) in women with BV and controls. RESULTS: Healthy vagina was free of biofilms. Prolific structured polymicrobial (StPM) Gardnerella-dominated biofilm characterised BV. The intact StPM-Gardnerellabiofilm enveloped desquamated va...

  1. Use of rotational fluoroscopy and 3-D reconstruction for pre-operative imaging of complex cloacal malformations.

    Patel, Manish N

    2016-04-01

    Complex cloacal malformations are associated with a wide spectrum of anatomic defects involving the gastrointestinal, urinary, and gynecologic tracts; the variety and complexity of these defects complicate surgical planning and repair. Rotational fluoroscopy with 3-D reconstruction provides precise anatomic detail, particularly regarding length of the common channel, appearance/location of the vagina(s) and bladder, which facilitates surgical planning and determination of prognosis. PMID:26969233

  2. 经阴道穿刺术患者的术前阴道冲洗护理%After preoperative vaginal vaginal puncture wash care patients

    张晓霞; 石嵩; 张婉菁

    2014-01-01

    Objective: To study the transvaginal puncture nursing experience in patients with preoperative vagina flushing. Methods: Retrospective in July 2011 to 2013, 4 menstrual vaginal proved to 325 cases, according to the vagina washing drug use and timing group, comparing group between the vagina washing effect. Results: The preoperative vaginal flush with iodine volts and physiological saline, vagina flushing effect had no significant difference (P>0.05), compared with preoperative patients with 24 hours flushing, patients with preoperative vagina flushing 48 hours, the incidence of vaginal residue increased significantly (P0.05),与术前24小时冲洗患者比较,术前48小时阴道冲洗患者,阴道分泌物残留发生率显著增加(P<0.01)。结论:对于经阴道穿刺术,术前24小时应用生理盐水阴道冲洗一次可以达到满意的效果。

  3. Vaginal position and length in the bitch: relationship to spaying and urinary incontinence.

    Gregory, S P; Holt, P E; Parkinson, T J; Wathes, C M

    1999-04-01

    A study was undertaken to determine if the vagina might be a suitable site for the measurement of intra-abdominal pressure during cystometry in the bitch. The position of the cranial vagina and vaginal length were measured radiographically and the effects of spaying and urinary incontinence on these variables were evaluated in 30 continent and 30 incontinent bitches. The study used retrograde vaginourethrograms which had been obtained from animals used in a previous study. The cranial vagina was intra-abdominal on 36 of the vaginourethrograms, being least commonly intra-abdominal in incontinent bitches (11/30). Vaginal position was related linearly to vaginal length and continence status (P < 0.01), while its length was related to bodyweight (P < 0.01). Allowing for bodyweight, neutered animals had significantly shorter vaginas than entire bitches (P < 0.01). Measurement of intra-abdominal pressure with concomitant measurement of intravesical pressure is essential if accurate assessment of detrusor pressure is to be determined during cystometry. The vagina is unlikely to be a useful location from which to measure intra-abdominal pressure since any pressure-measuring catheter inserted into it may fall outside the abdominal pressure zone. This is particularly true of neutered and/or incontinent bitches, the groups in which urodynamic investigations of urinary incontinence are most frequently indicated. PMID:10340249

  4. Herlyn Werner Wunderlich Syndrome with Hematocolpos: An Unusual Case Report of Full Diagnostic Approach and Treatment

    Rohit Bhoil

    2016-05-01

    Full Text Available Herlyn-Werner-Wunderlich (HWW syndrome is an uncommon combined müllerian duct anomalies (MDAs and mesonephric duct malformation of female urogenital tract characterized by uterus didelphys and obstructed hemi-vagina and ipsilateral renal agenesis (OHVIRA syndrome. We present a rare and unusual case of this syndrome in a 19 year-old female who suffered from hypomenorrhoea and abdominal pain. She had an obstructed hemi-vagina on right side which led to marked distention of ipsilateral cervix, while proximal hemi-vagina compressed the contralateral side causing its partial obstruction resulting in hypomenorrhoea. Understanding the imaging findings of this rare condition is important for early diagnosis in order to prevent complications which may lead to infertility.

  5. Posterior vaginal wall cyst of Mullerian origin: a case report

    Sunita Samal

    2015-02-01

    Full Text Available Cystic lesions of vagina are relatively uncommon and an incidental finding during routine gynaecological examination. Mullerian cysts are congenital cysts of vagina, usually reported during childbearing age group. These cysts mostly arise at the level of cervix and extend anteriorly in relation to bladder, but very rarely they may also extend posteriorly. This is a rare case of posterior vaginal wall cyst of Mullerian origin. A 36-year-old multi para (P2L2 both SVD, presented with a mass descending through vagina since 2-3 months. Pelvic examination revealed a 5x5 cm cystic mass arising from the posterior vaginal wall. Complete excision of the cyst was done. The cyst was filled with chocolate coloured material and histopathology confirmed a Mullerian cyst. [Int J Reprod Contracept Obstet Gynecol 2015; 4(1.000: 245-246

  6. Abnormal vaginal microbiota may be associated with poor reproductive outcomes: A prospective study in IVF patient

    Haahr, Thor; Al Humaidan, Peter Samir Heskjær

    2016-01-01

    Background: Bacterial vaginosis (BV) has a prevalence of approximately 19% in the infertile population. BV is often sub-clinical, characterized by a dysbiosis with anaerobic and facultative anaerobic bacteria, such as Gardnerella (g) vaginalis and Atopobium (a) vaginae. Few studies have been...... primers were specific for four common Lactobacillus spp., G. vaginalis and A. vaginae. Results: The prevalence of BV defined by Nugent score was 21% (27/130), whereas the prevalence of an abnormal vaginal microbiota was 28% (36/130) defined by qPCR with high concentrations of G. vaginalis and/or A....... vaginae. The qPCR diagnostic approach had a sensitivity and specificity of 93% and 93% for Nugent-defined BV. Eighty-four patients completed IVF treatment. The overall clinical pregnancy rate was 35% (29/84). Interestingly, only 9% (2/22) with qPCR defined abnormal vaginal microbiota obtained a clinical...

  7. Herlyn Werner Wunderlich Syndrome with Hematocolpos: An Unusual Case Report of Full Diagnostic Approach and Treatment.

    Bhoil, Rohit; Ahluwalia, Ajay; Chauhan, Narvir

    2016-01-01

    Herlyn-Werner-Wunderlich (HWW) syndrome is an uncommon combined müllerian duct anomalies (MDAs) and mesonephric duct malformation of female urogenital tract characterized by uterus didelphys and obstructed hemi-vagina and ipsilateral renal agenesis (OHVIRA) syndrome. We present a rare and unusual case of this syndrome in a 19 year-old female who suffered from hypomenorrhoea and abdominal pain. She had an obstructed hemi-vagina on right side which led to marked distention of ipsilateral cervix, while proximal hemi-vagina compressed the contralateral side causing its partial obstruction resulting in hypomenorrhoea. Understanding the imaging findings of this rare condition is important for early diagnosis in order to prevent complications which may lead to infertility. PMID:27123211

  8. HERLYN - WERNER - WUNDERLICH SYNDROME (HWW SYNDROME: A CASE REPORT

    Pallavi S

    2015-08-01

    Full Text Available Congenital anomalies of the mullerian duct system can result in various urogenital anomalies and, Herlyn Werner Wunderlich syndrome (HWW syndrome is one such rare anomaly . This syndrome is characterized by uterus didelphys with blind hemi vagina and ipsilateral renal agenesis . 1 it is also known as OHVIRA (Obstructed Hemi vagina with Ipsilateral Renal Anomaly syndrome . 2 Mullerian anomalies are frequently associated with renal anomalies, the incidence ranges from 0.2 to 7.4%. 3 Diagnosis of this condition is rarely made in prepubertal girls, and rather it is diagnosed after menarche. Common clinical presentation is pelvic pain shortly after menarche with an associated vaginal or pelvic mass. 4 this triad of obstructed hemi vagina, uterus didelphys and ipsilateral renal agenesis was first reported in 1950.

  9. A rare case of Turner′s syndrome presenting with Mullerian agenesis

    Suresh Vaddadi

    2013-01-01

    Full Text Available Turner′s syndrome also called as Ullrich Turner′s syndrome, is a disease of unclear pathogenesis characterized by complete or partial absence of one sex chromosome, with or without cell line mosaicism in a phenotypic female with short stature. Various anomalies result in a constellation of features, of which the most disturbing is primary amenorrhea due to gonadal dysgenesis. Hormone therapy in these patients can often result in successful menstruation, and scope for subsequent pregnancy because of anatomically normal uterus and vagina. Coexisting Mullerian agenesis in these patients can jeopardize the chances of future pregnancy as they have associated structural abnormalities of the uterus and vagina. We report a rare case of middle-aged female with Turner′s syndrome and Mullerian agenesis having absent secondary sexual characters and missing uterus with incompletely formed vagina.

  10. Anatomia e histologia do conduto genital feminino de Pomacea canaliculata (Lamarck, 1822 (Mollusca, Gastropoda, Pilidae

    Eliana de Fátima Marques de Mesquita

    1990-01-01

    Full Text Available In this paper the authors give an anatomical and histological analysis of the genital duct in mature and immature females of Pomacea canaliculata (Lamarck, 1822. Anatomically, the vagina has an equal dimension in its extension, varying in form and volume, according to the maturation period. In the immaturity, it has a smaller diameter and volume. In the maturity, the vagina increases in volume, having the aspect of a tumescent organ, and in certain specimens shows an albuminous pink thread in its lumen. Histologically, the calcigenic activity of the gland is evidentiated by the presence of an amorphous and basophilic mass, without nuclear material. This material has a fragmented aspect in the vagina lumen that reacts positively in van Kossa's coloured preparations for calcareous salts.

  11. A rare case of Turner's syndrome presenting with Mullerian agenesis.

    Vaddadi, Suresh; Murthy, Ramana S V; Rahul, C H; Kumar, Vinod L

    2013-10-01

    Turner's syndrome also called as Ullrich Turner's syndrome, is a disease of unclear pathogenesis characterized by complete or partial absence of one sex chromosome, with or without cell line mosaicism in a phenotypic female with short stature. Various anomalies result in a constellation of features, of which the most disturbing is primary amenorrhea due to gonadal dysgenesis. Hormone therapy in these patients can often result in successful menstruation, and scope for subsequent pregnancy because of anatomically normal uterus and vagina. Coexisting Mullerian agenesis in these patients can jeopardize the chances of future pregnancy as they have associated structural abnormalities of the uterus and vagina. We report a rare case of middle-aged female with Turner's syndrome and Mullerian agenesis having absent secondary sexual characters and missing uterus with incompletely formed vagina. PMID:24672170

  12. Clear Cell Carcinoma Presented as a Large Polypoid Mass Expanding the Vaginal Fornix: Report of Two Cases

    Kim, Ji Young; Cho, Jae Ho [Dept. of Radiology, College of Medicine, Yeungnam University, Daegu (Korea, Republic of)

    2012-11-15

    Primary clear cell carcinoma of the vagina or uterine cervix is a very rare tumor. We report radiologic findings of two cases of clear cell carcinoma, arising in the vagina and uterine cervix in a 16-year-old and a 26-year-old female. These were presented as a large polypoid mass with a stalk and expanding the vaginal fornix. One case with ultrasonography showed relatively homogeneous echoic solid mass; the other case with a CT showed heterogeneously and strongly enhancing mass. All of the two cases showed non-specific signal intensity with heterogeneous and strong enhancement on MRI.

  13. Scientific Rationale and Algorithmization of Sochi Resort Natural and Preformed Physical Therapeutic Factors in the Course of Combined Treatment of Patients with Chronic Vulvovaginitis

    Kirill V. Gordon

    2012-11-01

    Full Text Available Chronic vulvovaginitis is the most wide-spread gynecological pathology among women of childbearing age. The chief causations of nonspecific vulvovaginitis are reduction in oestrogen, disturbances in vaginal acidity, intestine dysbacteriosis, local and general immune disturbances. The growth of vagina opportunistic pathogenic flora is closely connected with the increase of bacterial slimes on vagina mucus. Sulphur balneotherapy in the form of general baths and vaginal irrigations, mechanical physiotherapy promotes disruption of bacterial slimes, oestrogen elevation, immune reconstruction and vaginal biocenosis, which has positive effect on patients’ fertility level, frequency of obstetrical and perinatal pathologies.

  14. Clear Cell Carcinoma Presented as a Large Polypoid Mass Expanding the Vaginal Fornix: Report of Two Cases

    Primary clear cell carcinoma of the vagina or uterine cervix is a very rare tumor. We report radiologic findings of two cases of clear cell carcinoma, arising in the vagina and uterine cervix in a 16-year-old and a 26-year-old female. These were presented as a large polypoid mass with a stalk and expanding the vaginal fornix. One case with ultrasonography showed relatively homogeneous echoic solid mass; the other case with a CT showed heterogeneously and strongly enhancing mass. All of the two cases showed non-specific signal intensity with heterogeneous and strong enhancement on MRI.

  15. CONGENITAL VESICOUTERINE FISTULA ALONG WITH DISTAL VAGINAL AGENESIS, SOLITARY KIDNEY AND TONGUE TIE: A RARITY

    Khalid

    2015-11-01

    Full Text Available : Congenital vesicouterine fistula in association with vaginal agenesis and solitary renal agenesis has been rarely reported. We present a case of 19 year old female suffering from cyclical menouria for last years. Physical examination revealed absence of vagina. IVP revealed left renal agenesis and CT scan revealed left renal agenesis with vesicouterine fistula. Cystoscopy showed vesicouterine fistula located above trigone near midline. Vesicouterine fistula was repaired along with uterine preservation. Sigmoid colon neovagina was created. Patient is doing well and menstruating per vagina till last followup

  16. A rare case of Mayer-Rokitansky-Kuster-Hauser syndrome with multiple leiomyomas in hypoplastic uterus

    Kulkarni, Maithili Mandar; Deshmukh, Sanjay D.; Hol, Kishor; Nene, Neha

    2015-01-01

    Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome is a rare disorder described as aplasia or hypoplasia of uterus and vagina due to an early arrest in development of mullerian ducts. Women with this syndrome are characterized by the presence of 46 XX karyotype, normal female secondary sex characters, normal ovarian functions, and underdeveloped vagina. The presence of leiomyoma in MRKH syndrome is very rare, and only few cases have been reported in the literature. Here, we report a case of MRKH syndrome with multiple leiomyomas originating from the rudimentary horn of uterus in 25 years married, phenotypically female patient. PMID:26752861

  17. Multikulturní dialog v Monologu o vaginach

    Uhde, Zuzana

    2005-01-01

    Roč. 6, č. 1 (2005), s. 39-40. ISSN 1213-0028 R&D Projects: GA AV ČR(CZ) 1QS700280503 Institutional research plan: CEZ:AV0Z70280505 Keywords : Vagina Monologues * gender justice * multiculturalism Subject RIV: AO - Sociology, Demography www.genderonline.cz

  18. Trachelectomy for cancer of the cervix: dargent's operation. Vaginal hysterectomy for early cancer of the cervix stage IA1 and CIN III

    Ottosen, Christian

    2011-01-01

    obstetrical outcomes. The procedure is a combination of laparoscopy for pelvic lymphadenectomy and challenging classic vaginal surgery to resect the tumour, part of the parametrium and upper vagina. Complications are in the range of 8-13%. Recurrence and death occur in 5 and 3%, respectively, as good...

  19. Preliminary data on the presence of bacteria in the uterus of pregnant cows

    Pedersen, H. G.; Knudsen, Lif Rødtness Vesterby; Agerholm, J. S.;

    2015-01-01

    of bacteria in the pregnant uterus may suggest that a cow can carry a pregnancy despite the presence of few potentially pathogenic bacteria or that normal flora exist in the uterus as in, for example, the vagina. In conclusion, bacteria were present in the endometrium and placentomes of pregnant cows. Further...

  20. Cáncer de vagina—Versión para profesionales de salud

    Información del Instituto Nacional del Cáncer para profesionales de salud sobre el tratamiento del cáncer de vagina, así como referencias a estudios clínicos, investigación y otros temas relacionados con este tipo de cáncer.

  1. Antibiotic Administration and Factors Influencing the Vaginal Microbiota during Pregnancy

    Stokholm, Jakob

    2012-01-01

    . The low pH level is together with the host immunity responsible for protection of the vagina. A vast number of other bacterial species are represented in the vaginal commensal microbiota and among these both Staphylococcus and E. coli are often found. Skewing of the vaginal commensal flora...

  2. Recommendations for the management of postmenopausal vaginal atrophy

    Sturdee, D W; Panay, N; Ulrich, Lian

    2010-01-01

    Unlike hot flushes and night sweats which resolve spontaneously in time, atrophic symptoms affecting the vagina and lower urinary tract are often progressive and frequently require treatment. The prevalence of vaginal dryness increases as a woman advances through the postmenopausal years, causing...

  3. Diagnosis and treatment of fistulising Crohn's disease

    Hvas, Christian Lodberg; Dahlerup, Jens Frederik; Jacobsen, Bent Ascanius;

    2011-01-01

    A fistula is defined as a pathological connection between the intestine and an inner (bladder or other intestine) or outer (vagina or skin) epithelial surface. Fistulas are discovered in up to 25% of all Crohn's disease patients during long-term follow-up examinations. Most are perianal fistulas...

  4. Pituitary adenylate cyclase-activating polypeptide: occurrence and relaxant effect in female genital tract

    Steenstrup, B R; Alm, P; Hannibal, J;

    1995-01-01

    tract. The highest concentrations of PACAP-38 were detected in the ovary, the upper part of vagina, and the perineum. The concentrations of PACAP-27 were generally low, in some regions below the detection limit and in other regions 1 to 5% of the PACAP-38 concentrations. Immunocytochemistry revealed...

  5. Protection against Chlamydia trachomatis infection and upper genital tract pathological changes by vaccine-promoted neutralizing antibodies directed to the VD4 of the major outer membrane protein

    Olsen, Anja W.; Follmann, Frank; Erneholm, Karin Susanne;

    2015-01-01

    bacterial numbers in vagina and prevention of pathological changes in the upper genital tract. Adoptive transfer of serumand T-cell depletion experiments demonstrated a dominant role for antibodies and CD4+ T cells in the protective immune response. Integrating a multivalent VD4 construct into the sequence...

  6. Bacterial vaginosis diagnosed by analysis of first-void-urine specimens

    Datcu, Raluca; Gesink, Dionne; Mulvad, Gert;

    2014-01-01

    . The FVU and vaginal swabs were analyzed by quantitative PCRs (qPCRs) for selected vaginal bacteria (Atopobium vaginae, Prevotella spp., Gardnerella vaginalis, bacterial vaginosis-associated bacterium 2, Eggerthella-like bacterium, "Leptotrichia amnionii," Megasphaera type 1), and all had an area under...

  7. Cáncer de vagina—Versión para pacientes

    Información del Instituto Nacional del Cáncer sobre el tratamiento del cáncer de vagina, así como referencias a estudios clínicos, investigación y otros temas relacionados con este tipo de cáncer.

  8. NKT cell activation by local α-galactosylceramide administration decreases susceptibility to HSV-2 infection

    Iversen, Marie Beck; Jensen, Simon Kok; Hansen, Anne Louise;

    2015-01-01

    that received local pre-treatment with αGalCer prior to intra-vaginal HSV-2 infection had a lower mean disease score, mortality and viral load in the vagina following infection, compared to mice that did not receive αGalCer pre-treatment. Further, we found increased numbers of CD45 and NK1.1 positive cells...

  9. Treatment with tibolone partially protects 3-D microarchitecture of lumbar Vertebral Bone Tissues and Prevents Ovariectomy-induced Reduction in Mechanical Properties

    Ding, Ming

    Treatment with Tibolone partially Protects 3-D Microarchitecture of Lumbar Vertebral Bone Tissues and Prevents Ovariectomy-induced Reduction in Mechanical Properties Tibolone (Org OD14) is a tissue selective steroid with estrogenic effects on the brain, bone and vagina, without stimulating...

  10. Associations of Filaggrin Gene Loss-of-Function Variants and Human Papillomavirus-Related Cancer and PreCancer in Danish Adults

    Skaaby, Tea; Husemoen, Lise Lotte N; Jørgensen, Torben;

    2014-01-01

    to human papillomavirus (HPV) infection and thus a higher risk of HPV-related cancer and pre-cancer. We investigated the association of the FLG genotype with incidence of HPV-related cancer of cervix, vagina, vulva, penis, anus and head and neck, and pre-cancer of the cervix. METHODS: We included 13...

  11. Antenatal MR diagnosis of urinary hydrometrocolpos due to urogenital sinus

    Subramanian, Subramanian; Sharma, Raju; Gamanagatti, Shivanand [All India Institute of Medical Sciences, Department of Radiodiagnosis, New Delhi (India); Agarwala, Sandeep [All India Institute of Medical Sciences, Department of Pediatric Surgery, New Delhi (India); Gupta, Prerna; Kumar, Sunesh [All India Institute of Medical Sciences, Department of Obstetrics and Gynaecology, New Delhi (India)

    2006-10-15

    Hydrometrocolpos is cystic dilatation of the vagina and uterus due to congenital vaginal obstruction. It may be secretory or urinary in character and manifests in the neonatal period with abdominal distension. Urinary hydrometrocolpos occurs in patients with urogenital sinus or cloacal anomaly. A rare case of antenatal MR diagnosis of urinary hydrometrocolpos due to urogenital sinus is presented. (orig.)

  12. Expression of C4.4A, a structural uPAR homolog, reflects squamous epithelial differentiation in the adult mouse and during embryogenesis

    Kriegbaum, Mette Camilla; Jacobsen, Benedikte; Hald, Andreas;

    2011-01-01

    -glandular portion of the rodent stomach, anus, vagina, cornea, and skin. This epithelial confinement was particularly evident from the abrupt termination of C4.4A expression at the squamo-columnar transition zones found at the ano-rectal and utero-vaginal junctions, for example. During mouse embryogenesis, C4.4A...

  13. β-Microseminoprotein endows post coital seminal plasma with potent candidacidal activity by a calcium- and pH-dependent mechanism

    Edström Hägerwall, Anneli; Rydengård, Victoria; Fernlund, Per;

    2012-01-01

    The innate immune factors controlling Candida albicans are mostly unknown. Vulvovaginal candidiasis is common in women and affects approximately 70-75% of all women at least once. Despite the propensity of Candida to colonize the vagina, transmission of Candida albicans following sexual intercourse...

  14. Ear acupuncture or local anaesthetics as pain relief during postpartum surgical repair: a randomised controlled trial

    Kindberg, S; Klünder, L; Strøm, J;

    2009-01-01

    with approximately 1600 annual deliveries. Population Primiparous women with a vaginal delivery at term who needed surgical repair of lacerations to the labia or the vagina, perineal lacerations of first or second degree or mediolateral episiotomies. Methods The trial was set up to evaluate the effect of a brief 2...

  15. Perivaskulær epiteloidcelletumor i uterus

    Nguyen Knudsen, Kirsten Quyen; Winter, Pia Engell; Lykkebo, Annemette Wildfang;

    2013-01-01

    Perivascular epithelioid cell tumours (PEComas) are rare tumours with unknown malignant potential. We report a case of a 48-year-old woman, who had had many tumours, initially diagnosed as leiomyomas, removed from her uterus and vagina over 16 years. A recurrent tumour and revision of prior...

  16. Loss of a novel mucin-like epithelial glycoprotein in oral and cervical squamous cell carcinomas

    Nielsen, P A; Mandel, U; Therkildsen, M H;

    1997-01-01

    layers of buccal epithelium and was also found in larynx, esophagus, vagina, and exocervix, but not in epidermis. Data showed that gp230 was distinct from MUC1 or CD44. It is interesting that in most cases gp230 was not expressed in squamous cell carcinomas of buccal and cervical mucosa. A few moderately...

  17. Detection of spermatozoa following consensual sexual intercourse

    Astrup, Birgitte Schmidt; Thomsen, Jørgen Lange; Lauritsen, Jens;

    2012-01-01

    place during their latest intercourse, a significant number (14%) had spermatozoa in the vagina. CONCLUSION: Spermatozoa were best recovered from the posterior fornix, but spermatozoa were also present on swabs taken from the external genitalia. Detection of spermatozoa is thus possible in cases where...

  18. Childhood lichen sclerosus is a rare but important diagnosis

    Jensen, Lise Soldbro; Bygum, Anette

    2012-01-01

    Lichen sclerosus (LS) is a chronic skin disorder with a predilection for the anogenital area. The disease is mostly seen in prepubertal and postmenopausal females. The lesions present as sharply demarcated white plaques encircling the vagina and anus. The atrophic form can lead to scarring...

  19. The vaginal microbiome is stable in prepubertal and sexually mature Ellegaard Göttingen Minipigs throughout an estrous cycle

    Lorenzen, Emma; Kudirkiene, Egle; Gutman, Nicole;

    2015-01-01

    environment and the fate of sexually transmitted infections such as Chlamydia trachomatis infections. Therefore, knowledge on the vaginal microbiota is urgently needed for the minipig model. The aim of this study was to characterize the microbiota of the anterior vagina by 16 s rRNA gene sequencing...

  20. Practice patterns of radiotherapy in endometrial cancer among member groups of the gynecologic cancer intergroup

    Small, W.Jr.; Bois, A. Du; Bhatnagar, S.;

    2009-01-01

    .57 [10.13] Gy in a mean of 4.3 insertions), and 5 groups used low-dose-rate brachytherapy (41.45 [17.5] Gy). Nineteen of the 28 respondents measured the doses to the bladder and the rectum when performing VBT. For brachytherapy, there was no uniformity in the fraction of the vagina treated or the doses...

  1. Surfactant protein D in the female genital tract

    Leth-Larsen, Rikke; Floridon, C; Nielsen, O;

    2004-01-01

    -D indicating a systemic role for the protein. This study describes the presence of SP-D in the female genital tract, the placenta and in amniotic fluid using immunohistochemistry and enzyme-linked immunosorbent assay. SP-D was observed in cells lining surface epithelium and secretory glands in the vagina...

  2. Covered exstrophy with anorectal malformation and vaginal duplication

    Bawa Monika

    2011-01-01

    Full Text Available Covered exstrophy is a rare variant of the exstrophy-epispadias complex. We report a female newborn with covered exstrophy, absent anal opening and duplication of the introitus and the lower vagina. This rare, previously unreported, combination of anomalies highlights the complexity of the embryological events in the caudal area during separation of the hindgut and allantois.

  3. Biofeedback and physiotherapy versus physiotherapy alone in the treatment of genuine stress urinary incontinence

    Glavind, K; Nøhr, S B; Walter, S

    1996-01-01

    Biofeedback is a method of pelvic floor rehabilitation using a surface electrode inserted into the vagina and a catheter in the rectum. Forty women with genuine urinary stress incontinence were randomized to compare the efficacy of physiotherapy and physiotherapy in combination with biofeedback...

  4. The surgical team as a source of postoperative wound infections caused by Streptococcus pyogenes

    Kolmos, H J; Svendsen, R N; Nielsen, S V

    1997-01-01

    surgeons and obstetricians. In outbreaks where an attack rate could be calculated, it was at least 7%. T-28 was the most commonly involved T-type, accounting for seven outbreaks. The anus and vagina were the most common carrier sites in staff members. A combination of penicillin and oral vancomycin seemed...

  5. SPINAL ABNORMALITIES AND THE ATYPICAL FORM OF THE MAYER-ROKITANSKY-KUSTER-HAUSER SYNDROME

    STRUBBE, EH; LEMMENS, JAM; THIJN, CJP; WILLEMSEN, WNP; VANTOOR, BSJ

    1992-01-01

    In 96 patients with congenital absence of the uterus and upper vagina, the Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome, it proved possible to distinguish between the typical and the atypical form using laparoscopy. The typical form was characterized by symmetrical nonfunctioning muscular buds (th

  6. Robot-Assisted Gynecologic Oncology Surgery

    Full Text Available ... it out through the vagina. So there's a number of ways to do this. And we've used this with reasonable satisfaction. Lisa, whenever you're ready, we're ready to retrieve the lymph nodes. This first specimen will be right pelvic lymph node, so ...

  7. Single stage management of a unique variant of congenital pouch colon with triplet fistula and normal anus.

    Pandey, Vaibhav; Gangopadhyay, Ajay Narayan; Gupta, Dinesh Kumar; Sharma, Shiv Prasad

    2015-01-01

    Congenital pouch colon (CPC) in the female patient presents with highly variable and anomalous anatomy. We herein report the first case of CPC with uterus didelphys having normal anal opening, H-type vestibular fistula, two other fistulous communications between pouch colon and two vagina managed in a single stage with excellent postoperative outcome. PMID:26166988

  8. Uterine didelphys with cervical incompetence

    Aher Gautam S, Gavali Urmila G, Kulkarni Meghana

    2013-01-01

    Uterine didelphys represents a uterine malformation where the uterus is present as a paired organ. There is presence of double uterine bodies with two separate cervices, and often a double or septate vagina as well. We report a case of single pregnancy in the right sided uterine body of a didelphic uterus with cervical incompetence.

  9. Single stage management of a unique variant of congenital pouch colon with triplet fistula and normal anus

    Pandey, Vaibhav; Gangopadhyay, Ajay Narayan; Gupta, Dinesh Kumar; Sharma, Shiv Prasad

    2015-01-01

    Congenital pouch colon (CPC) in the female patient presents with highly variable and anomalous anatomy. We herein report the first case of CPC with uterus didelphys having normal anal opening, H-type vestibular fistula, two other fistulous communications between pouch colon and two vagina managed in a single stage with excellent postoperative outcome.

  10. Uterine didelphys with cervical incompetence

    Aher Gautam S, Gavali Urmila G, Kulkarni Meghana

    2013-04-01

    Full Text Available Uterine didelphys represents a uterine malformation where the uterus is present as a paired organ. There is presence of double uterine bodies with two separate cervices, and often a double or septate vagina as well. We report a case of single pregnancy in the right sided uterine body of a didelphic uterus with cervical incompetence.

  11. Primary Gonorrhea Infection

    ... is typically displayed as a discharge from the penis, while redness and an ulceration on the tip of the penis can also be displayed, as seen in this ... a thick, cloudy, or bloody discharge from the penis, vagina, or rectum; or pain with sexual intercourse. ...

  12. Reactivity to human papillomavirus type 16 Ll virus-like particles in sera from patients with genital cancer and patients with carcinomas at five different extragenital sites

    G.J.J. van Doornum (Gerard); C.M. Korse (Catharina); J.C.G.M. Buning-Kager (J. C G M); J.M. Bonfrer (Hans); S. Horenblas (Simon); B. Taal (Babs); J. Dillner (Joakim)

    2003-01-01

    textabstractA retrospective seroepidemiologic study was performed to examine the association between human papillomaviruses (HPV) 16 infection and carcinomas of the oropharynx, the oesophagus, penis and vagina. Sera were selected from the serum bank from the Antoni van Leeuwenhoek Hospital (Netherla

  13. Endometriosis

    Full Text Available ... In severe cases, endometriosis can grow into other organs including the intestines, bladder, vagina and ureters, which are the tubes from the kidney to the bladder. Although it’s rare, endometriosis can be found outside the pelvic cavity in almost any location in the body. Rarely, ...

  14. Aggressive Angiomyxoma

    Padmavathy, L.; L Lakshmana Rao; M Dhana Lakshmi; N Sylvester

    2014-01-01

    Myxoid tumors are a heterogeneous group of lesions characterized by a marked abundance of extra cellular mucoid (myxoid) matrix. [1] The term aggressive emphasizes the often infiltrative nature of the tumor and its frequent association with recurrence. [2] A case of aggressive angiomyxoma arising from the vagina in a 55-year-old woman is reported for its rarity.

  15. Posterior vaginal wall Gartner′s duct cyst

    Ripan Bala

    2015-01-01

    Full Text Available Cyst of posterior vaginal wall is very rare. This case relates to a patient who presented with polypoidal mass protruding out from vagina which could have been easily mistaken as uterovaginal prolapse, but appropriate clinical evaluation supported with investigations clinched the diagnosis easily.

  16. Oxytocin determination by radioimmunoassay in cattle. 2

    Oxytocin concentration in jugular vein blood was measured radioimmunologically with a detection limit of 3 pg/ml plasma in male and female cattle. Five bulls were tested; during mating a cow in oestrus with intromission and ejaculation, during mounting a dummy or another bull with ejaculation into an artificial vagina or during false mounts. No increase in oxytocin concentrations could be observed, but stimulation with an electro-ejaculator caused an increase ranging from 5-84 pg/ml after a latent period of 3-5 min. A similar response was observed in two cows following the same procedure. The contact with a bull, false mount or mating with intromission and ejaculation was not followed by a measurable oxytocin release in 5 test cows. The following stimulation techniques, massage of vulva and clitoris, massage of cervix and uterus per rectum, artificial insemination, introduction of a speculum into the vagina or insufflation of air into the vagina were performed with 5 cows and 5 heifers. Insufflation of air into the vagina was the most effective stimulus, eleciting an oxytocin release up to 588 pg/ml. All 5 heiers responded positively, as well as 4 cows in oestrus. The other manipulations cuased an oxytocin response mainly in heifers (whether in oestrus or dioestrus), whereas only one cow in oestrus responded with an oxytocin release. In general, oxytocin concentrations increase about 30-90 s after the start of the stimulus. (author)

  17. Oxytocin determination by radioimmunoassay in cattle. 2. Effect of mating and stimulation of the genital tract in bulls, cows and heifers

    Schams, D.; Baumann, G. (Institut fuer Physiologie der Sueddeutschen Versuchs- und Forschungsanstalt fuer Milchwirtschaft der TU Muenchen); Leidl, W. (Gynaekologische und Ambulatorische Tierklinik der Universitaet Muenchen, Germany)

    1982-01-01

    Oxytocin concentration in jugular vein blood was measured radioimmunologically with a detection limit of 3 pg/ml plasma in male and female cattle. Five bulls were tested; during mating a cow in oestrus with intromission and ejaculation, during mounting a dummy or another bull with ejaculation into an artificial vagina or during false mounts. No increase in oxytocin concentrations could be observed, but stimulation with an electro-ejaculator caused an increase ranging from 5-84 pg/ml after a latent period of 3-5 min. A similar response was observed in two cows following the same procedure. The contact with a bull, false mount or mating with intromission and ejaculation was not followed by a measurable oxytocin release in 5 test cows. The following stimulation techniques, massage of vulva and clitoris, massage of cervix and uterus per rectum, artificial insemination, introduction of a speculum into the vagina or insufflation of air into the vagina were performed with 5 cows and 5 heifers. Insufflation of air into the vagina was the most effective stimulus, eleciting an oxytocin release up to 588 pg/ml. All 5 heiers responded positively, as well as 4 cows in oestrus. The other manipulations cuased an oxytocin response mainly in heifers (whether in oestrus or dioestrus), whereas only one cow in oestrus responded with an oxytocin release. In general, oxytocin concentrations increase about 30-90 s after the start of the stimulus.

  18. Healthy Sexuality

    Full Text Available ... body responds to sexual stimulation. During sexual arousal, blood flow increases to a woman’s genitals. Her vagina ... changes occur; a woman’s nipples become erect, her blood pressure and heart rate increase, and a “sex ...

  19. Clear cell renal cell carcinoma with vaginal and brain metastases: a case report and literature review

    Tobe Samuel Momah; Dhanan Etwaru; Phillip Xiao; Vasantha Kondamudi

    2009-01-01

    There are very few cases of clear cell renal cell carcinoma with metastases to the vagina and brain reported in the literature. Our case study highlights this rare clinical occurrence and its associated complications including pulmonary embolism. In addition we discuss current management guidelines for treating and diagnosing the disease, and how this management improves prognosis.

  20. Antenatal MR diagnosis of urinary hydrometrocolpos due to urogenital sinus

    Hydrometrocolpos is cystic dilatation of the vagina and uterus due to congenital vaginal obstruction. It may be secretory or urinary in character and manifests in the neonatal period with abdominal distension. Urinary hydrometrocolpos occurs in patients with urogenital sinus or cloacal anomaly. A rare case of antenatal MR diagnosis of urinary hydrometrocolpos due to urogenital sinus is presented. (orig.)

  1. Aggressive angiomyxoma.

    Padmavathy, L; Rao, L Lakshmana; Lakshmi, M Dhana; Sylvester, N

    2014-04-01

    Myxoid tumors are a heterogeneous group of lesions characterized by a marked abundance of extra cellular mucoid (myxoid) matrix.[1] The term aggressive emphasizes the often infiltrative nature of the tumor and its frequent association with recurrence.[2] A case of aggressive angiomyxoma arising from the vagina in a 55-year-old woman is reported for its rarity. PMID:24860748

  2. Aggressive Angiomyxoma

    L Padmavathy

    2014-01-01

    Full Text Available Myxoid tumors are a heterogeneous group of lesions characterized by a marked abundance of extra cellular mucoid (myxoid matrix. [1] The term aggressive emphasizes the often infiltrative nature of the tumor and its frequent association with recurrence. [2] A case of aggressive angiomyxoma arising from the vagina in a 55-year-old woman is reported for its rarity.

  3. Disseminated cutaneous rhinosporidiosis in a HIV sero - positive patient

    Padmavathy L; Rao I; Selvam Siva; Sahoo C

    2001-01-01

    Rhinosporidiosis is a chronic disease, classically involving the nose and nasopharynx, clinically presenting as polypii. However,disseminated rhinosporidiosis, involving various other sites including lips, conjunctiva, uvula, vagina, larynx. trachea. scalp and skin is also known to occur. A case of rhinosporidiosis, with nasal, oropharyngeal and multiple cutaneous lesions, in a patient who is sera - positivafor HIV is reported.

  4. Disseminated cutaneous rhinosporidiosis in a HIV sero--positive patient.

    Padmavathy, L; Rao, I L; Selvam, S S; Sahoo, C G

    2001-01-01

    Rhinosporidiosis is a chronic disease, classically involving the nose and nasopharynx, clinically presenting as polypii. However,disseminated rhinosporidiosis, involving various other sites including lips, conjunctiva, uvula, vagina, larynx. trachea. scalp and skin is also known to occur. A case of rhinosporidiosis, with nasal, oropharyngeal and multiple cutaneous lesions, in a patient who is sero--positive for HIV is reported. PMID:17664794

  5. Disseminated cutaneous rhinosporidiosis in a HIV sero - positive patient

    Padmavathy L

    2001-11-01

    Full Text Available Rhinosporidiosis is a chronic disease, classically involving the nose and nasopharynx, clinically presenting as polypii. However,disseminated rhinosporidiosis, involving various other sites including lips, conjunctiva, uvula, vagina, larynx. trachea. scalp and skin is also known to occur. A case of rhinosporidiosis, with nasal, oropharyngeal and multiple cutaneous lesions, in a patient who is sera - positivafor HIV is reported.

  6. AcEST: BP919927 [AcEST

    Full Text Available tr|B7S227|B7S227_9GAMM Molybdate ABC transporter, periplasmic mo... 33 7.2 >tr|A9... OS=Trichomonas vagina... 33 5.5 tr|B4JN38|B4JN38_DROGR GH24212 OS=Drosophila grimshawi GN=GH2421... 33 7.2

  7. Your First Gynecologic Visit

    ... In this exam, the doctor looks at the vulva . He or she may give you a mirror so that you can look at the vulva as well. This exam is a good way ... exam has three parts: 1. Looking at the vulva 2. Looking at the vagina and cervix with ...

  8. Human papillomavirus-associated cancers: A growing global problem.

    Bansal, Anshuma; Singh, Mini P; Rai, Bhavana

    2016-01-01

    Human papillomavirus (HPV) infection is linked with several cancers such as cancer cervix, vagina, vulva, head and neck, anal, and penile carcinomas. Although there is a proven association of HPV with these cancers, questions regarding HPV testing, vaccination, and treatment of HPV-related cancers continue to remain unanswered. The present article provides an overview of the HPV-associated cancers. PMID:27127735

  9. Episiotomy

    ... Drugs & Supplements Videos & Tools Español You Are Here: Home → ... on this page, please enable JavaScript. An episiotomy is a minor surgery that widens the opening of the vagina during childbirth. It is a cut to the perineum -- the ...

  10. Episiotomy - aftercare

    ... Drugs & Supplements Videos & Tools Español You Are Here: Home → ... To use the sharing features on this page, please enable JavaScript. An episiotomy is a minor incision made during childbirth to widen the opening of the vagina. A ...

  11. Stages of Cervical Cancer

    ... flow from the body to a collection bag. Plastic surgery may be needed to make an artificial vagina ... in the second or third trimester of pregnancy. Surgery or radiation ... with your doctor about the effects of radiation on the fetus . It may be ...

  12. Condiloma Acuminado

    Juan Carlos Céspedes Escobar

    2011-06-01

    Full Text Available El Condilomas Acuminado es una enfermedadcausada por el Virus Papiloma Humano.Se caracteriza por el crecimiento de verrugas blandas en los genitales o en la regiónanal, o sea que crece entre los muslos y la parte interna de las nalgas, en el pene o en la vagina.

  13. Pregnancies from imipramine and xylazine-induced ex copula ejaculation in a disabled stallion.

    Card, C E; Manning, S T; Bowman, P; Leibel, T

    1997-01-01

    Breeding or semen collection was attempted using: natural cover, manual stimulation, artificial vagina, pharmacologic induction of ejaculation, and electroejaculation. Sperm cells were recovered from the ductus deferens and epididymides post mortem. Only semen collected ex copula by imipramine and xylazine treatment resulted in conceptions (4/5). This is the first report of pregnancies in horses from ex copula semen collection.

  14. Pharmacomicrobiomics: the impact of human microbiome variations on systems pharmacology and personalized therapeutics

    ElRakaiby, M.; Dutilh, B.E.; Rizkallah, M.R.; Boleij, A.; Cole, J.N.; Aziz, R.K.

    2014-01-01

    The Human Microbiome Project (HMP) is a global initiative undertaken to identify and characterize the collection of human-associated microorganisms at multiple anatomic sites (skin, mouth, nose, colon, vagina), and to determine how intra-individual and inter-individual alterations in the microbiome

  15. Pharmacomicrobiomics : the impact of human microbiome variations on systems pharmacology and personalized therapeutics

    ElRakaiby, Marwa; Dutilh, Bas E; Rizkallah, Mariam R; Boleij, Annemarie; Cole, Jason N; Aziz, Ramy K

    2014-01-01

    The Human Microbiome Project (HMP) is a global initiative undertaken to identify and characterize the collection of human-associated microorganisms at multiple anatomic sites (skin, mouth, nose, colon, vagina), and to determine how intra-individual and inter-individual alterations in the microbiome

  16. Group B Strep Infection

    MENU Return to Web version Group B Strep Infection Overview What is group B strep? Group B streptococcus, or group B strep for short, is a certain kind ... in the intestine, rectum, and vagina (in women). Group B strep doesn’t usually cause problems in ...

  17. Pre-natal innervation of the human female genital tract.

    Olfat, S A; Rahman, S A

    1978-01-01

    In the human fetus of 14 weeks, ganglia on either sides of the Müllerian uterovaginal canal contained two types of cells. In the 16th week, axons invaded the basal zone of the stratified squamous epithelium at the sides of the upper vagina. In the 20th week, vesicular nuclei typified the large neurons in the midportion of the cervico-vaginal ganglion. During the 22nd week, capsulated ganglia invaded the wall of the upper vagina forming three concentrically disposed strata. Non-capsulated clusters invaded its lamina propria. At the 24th week, axons were shaded after reaching the superficial zone of the stratified vaginal epithelium. In the 28th week, satellites surrounded the mature neurons and sheath cells enveloped the axons. Ganglia invaded the splitted muscle layer of the upper vagina at 30 weeks. Intraepithelial fibres invaded the whole thickness of the endometrium, the columnar epithelium of the cervix and uterine tube at 40 weeks. Nerve cells were detected among the basal epithelial cells of the lower vagina and its subepithelial plexus. PMID:665140

  18. Lactobacillus delbrueckii as the Cause of Urinary Tract Infection▿

    Darbro, Benjamin W.; Petroelje, Brian K.; Doern, Gary V.

    2008-01-01

    Lactobacilli are part of the normal bacterial flora of the vagina and are typically considered contaminants when cultured from urine specimens of female patients. Here we describe the case of a female patient with chronic pyuria and urinary tract symptoms in which Lactobacillus delbrueckii was determined to be the causative microorganism.

  19. Syndrome in question.

    Wu, Yinhua; Qiao, Jianjun; Fang, Hong

    2014-01-01

    Vulvovaginal-gingival syndrome is characterized by erosions and desquamation of the vulva, vagina, and gingiva. We reported a case of a 32-year-old woman presenting with an 8-year history of damage to the vulval and perianal anatomy and limitation of mouth opening. The patient's symptoms were relieved after treatment with topical tacrolimus cream. PMID:25184936

  20. 38 CFR 4.116 - Schedule of ratings-gynecological conditions and disorders of the breast.

    2010-07-01

    ... monthly compensation. 7610Vulva, disease or injury of (including vulvovaginitis). 7611Vagina, disease or... Reproductive Organs (diagnostic codes 7610 through 7615): Symptoms not controlled by continuous treatment 30 Symptoms that require continuous treatment 10 Symptoms that do not require continuous treatment...

  1. An unusual case of long standing vaginal foreign body removed with obstetric forceps

    Padmalata

    2015-04-01

    Full Text Available This is a case of retained foreign body in vagina for 10 years, a wood apple which was inserted to reduce uterine prolapse. It was retained without any symptoms for 10 years. The foreign body was removed using obstetric forceps after other methods were failed. [Int J Reprod Contracept Obstet Gynecol 2015; 4(2.000: 502-504

  2. Healthy Sexuality

    Full Text Available ... to sexual stimulation. During sexual arousal, blood flow increases to a woman’s genitals. Her vagina is lubricated ... become erect, her blood pressure and heart rate increase, and a “sex flush” from the stomach to ...

  3. Urogenital tumors

    Weller, R.E.

    1994-03-01

    An overview is provided for veterinary care of urogenital tumors in companion animals, especially the dog. Neoplasms discussed include tumors of the kidney, urinary bladder, prostate, testis, ovary, vagina, vulva and the canine transmissible venereal tumor. Topics addressed include description, diagnosis and treatment.

  4. Your First Pelvic Exam: A Guide for Teens

    ... started to develop Whether you have ever had sex or have been sexually abused If you have vaginal itchiness or an unusual discharge (drainage) or odor from your vagina Getting Ready: If you find it helpful, your mom, sister or friend can stay with you. There ...

  5. Orchidaceae novae malayenses XVII

    Smith, J.J.

    1943-01-01

    Planta florens 62—72 cm alta. Caulis inferne vaginatus, ceterum foliatus. Folia c. 8, lineari-lanceolata ad linearia, breviter acuminata ad sensim acutata, acuta, sicco membranacea, 12.5—14 cm longa, 1.8—1.1 cm lata, superiora decrescentia et sensim in bracteas vergentia; vaginae inferiores longe tu

  6. Draft Genome Sequence of Lactobacillus plantarum CMPG5300, a Human Vaginal Isolate

    Malik, S.; Siezen, R.J.; Renckens, B.; Vaneechoutte, M.; Vanderleyden, J.; Lebeer, S.

    2014-01-01

    The draft genome of a highly auto-aggregating Lactobacillus plantarum strain isolated from a human vagina is reported. The peculiar phenotype also provides an adhesive and co-aggregative potential with various pathogens, which could be of significance in the vaginal niche. Detailed genome analysis c

  7. An isolated vaginal metastasis from rectal cancer

    Ai Sadatomo

    2016-02-01

    Conclusion: We should keep the vagina within the field of view of pelvic MRI, which is one of the preoperative diagnostic tools for colorectal cancer. If female patients show gynecological symptoms, gynecological examination should be recommended. Isolated vaginal metastases are an indication for surgical resection, and adjuvant chemotherapy is also recommended.

  8. 环吡酮胺阴道栓对阴道粘膜刺激性和过敏性试验研究

    王小蒙; 艾涛; 符世托; 邝少轶

    2014-01-01

    目的:为了考察环吡酮胺阴道栓阴道粘膜用药的安全性。方法以家兔和豚鼠为观察对象,进行环吡酮胺阴道栓对家兔阴道粘膜刺激性试验和环吡酮胺阴道栓对豚鼠阴道粘膜过敏性试验。结果家兔完整阴道粘膜组和破损阴道粘膜组在连续7天接触受试药后,阴道粘膜均未见到异常分泌物,无充血、水肿和坏死等症状,病理检查,无炎症性细胞浸润和组织细胞坏死现象,表明环吡酮胺阴道栓对家兔完整阴道粘膜组和破损阴道粘膜组均无刺激性;豚鼠阴道粘膜接触环吡酮胺阴道栓致敏后14天激发,豚鼠阴道粘膜干净,未见异常分泌物,无充血、水肿。结论表明环吡酮胺阴道栓对豚鼠阴道粘膜无明显致敏。%Objective To investigate drug safety of ciclopirox olamine pessary for vagina mucosa .Method An irritation test with ciclopirox olamine pessary to vaginal mucosa of rabbit and hypersusceptibility test with ciclopirox olamine pessary to vagina mucosa of guinea pigs are performed .Result After continuously administration of ciclopirox olamine pessary for 7 days,the integrate vagina mucosa group and damaged vagina mucosa group of rabbits show no symptom of abnormal discharge ,hyperaemi-a,edema,necrosis,etc,and inflammatory cell accumulation and histiocytic necrotizing are not found in pathological examination ,indicating that ciclopirox olamine pessary has no irritation to vagina mucosa of rabbit in the both groups .After continuously allergia of ciclopirox olamine pessary for 14 days,vagina mucosa of guinea pig is clean showing no abnormal discharge and hyperaemia,which indicates that vagina mucosa of guinea pig.Conclusion It shows no hypersusceptibility to ciclopirox olamine pessa-ry.

  9. Efecto del método de obtención de semen de ovino sobre la calidad espermática (Effect of the method of obtaining of ovine semen on the spermatic quality

    Córdova-Izquierdo, Alejandro1*; ; ; y

    2006-08-01

    Full Text Available La colecta del semen del ganado ovino, ayuda a identificar problemas relacionados con el desempeño reproductivo de estos animales. Se han utilizado diferentes pruebas laboratoriales, para valorar la calidad seminal de los ovinos y poder realizar predicciones indirectas del potencial reproductivo de los machos reproductores; no obstante, su naturaleza subjetiva, no asegura el poder de fecundación de los machos. El objetivo de este trabajo fue valorar el efecto del método de obtención del semen de ovinos sobre la calidad espermática. Se empelaron 10 machos ovinos de la raza Suffolk de una Unidad de Producción Ovina, ubicada en el Estado de México, México. Para la recolección seminal se utilizó vagina artificial y directamente de la vagina, después de la monta natural. El semen fue valorado macro y microscópicamente. Los resultados promedios fueron, para vagina artificial: volumen 1.11 ml, pH 6.62, motilidad 64.5 %, concentración de espermatozoides/ml 206.4 x106, vivos 68.5 %, Muertos 31.87% y anormalidades 23.96%; directamente de la vagina: volumen 0.57 ml, pH 6.75, motilidad 60.4%, concentración de espermatozoides/ml 176.02 x 106, vivos 62.62 %, muertos 37.27% y anormalidades 11.12%. Los resultados indican que los resultados obtenidos con vagina artificial fueron los mejores. The collection of the semen of the livestock ovine, helps to identify problems related with the reproductive acting of these animals. They have been used different you prove laboratories, to value the seminal quality of the ovines and power to carry out indirect predictions of the reproductive potential of the reproductive males; nevertheless, its subjective nature, doesn't assure the power of fecundation of the males. The objective of this work was to value the effect of the method of obtaining of the ovines semen on the spermatic quality. You empelaron 10 male ovines of the race Suffolk of a Unit of Production Ovine, located in the State of Mexico, Mexico

  10. 实时三维超声诊断女性尿瘘的影像学方法%Imaging method by real-time three-dimensional ultrasound in diagnosis of female urinary ;fistula

    张逸仲

    2015-01-01

    目的:探讨实时三维超声诊断女性尿瘘的影像学方法。方法应用实时三维超声检查42例女性尿瘘患者,分别经腹部及会阴部观察女性膀胱-阴道间隔、尿道-阴道间隔矢状面和横断面的超声声像图表现,观测瘘口位置和大小,并作排尿试验或从尿道注入有色液体试验来证实。结果42例均可显示膀胱壁、尿道、阴道、膀胱-阴道间隔、尿道-阴道间隔全程矢状面及不同水平横断面的声像图,瘘口处均显示膀胱-阴道或者尿道-阴道局部融合,间隔组织缺失,回声中断,排尿试验或从尿道注入有色液体试验证实瘘口存在,术后验证位置及大小。结论实时三维超声检查女性尿瘘,通过女性膀胱-阴道间隔、尿道-阴道间隔在不同水平横断面及矢状面的超声表现,诊断和测量瘘口,结合病史及排尿试验或从尿道注入有色液体试验,对女性尿瘘临床诊断、治疗有重要作用。%Objective To investigate imaging method by real-time three-dimensional ultrasound in diagnosis of female urinary fistula. Methods Real-time three-dimensional ultrasound was applied for examination in 42 female patients with urinary fistula. Ultrasound images of sagittal plane and transverse plane of bladder-vagina interval and urethra-vagina interval through abdomen and perineum. Position and size of orificium fistulae were observed and verified by voiding trial or injection of colored liquid through urethra. Results All the 42 cases had images of full sagittal plane and partial transverse plane of bladder wall, urethra, vagina, bladder-vagina interval and urethra-vagina interval. Orificium fistulae all had meromixis of bladder-vagina or urethra-vagina, deficiency of interval organization, and suspended echo. Voiding trial or injection of colored liquid through urethra verified existence of orificium fistulae, and position and size were verified by operation. Conclusion Implement

  11. 先天性无阴道2例诊治比较

    杨晓妮

    2014-01-01

    目的:对两例先天性无阴道进行诊治并对治疗效果进行探讨。方法选取2011年10月~2012年4月正宁县人民医院收治的2例先天性无阴道患者,对其诊断方法及治疗的结果进行探讨分析。结果2例患者均手术成功,并且术后没发生感染,机体恢复正常。而随访中,采用真皮补片进行阴道再造的患者人工阴道完全黏膜化,效果颇佳;另1例患者因为未按要求进行阴道模具的使用,6个月后出现了阴道粘连,再次入院进行阴道扩张后,阴道恢复正常,可满足其性生活需求。结论本次对2例患者分别进行了真皮补片阴道再造及腹膜代阴道的阴道再造手术,效果较好,值得临床推广应用。%Objective To discuss and analyze the diagnosis an treatment and the effect of 2 patients with congenital absence of vagina.Method Clinical data about 2 patients with congenital absence of vagina admitted to the hospital from October 2011 to April 2012 were retrospectively analyzed,discussed the diagnosis methods and treatment rsults.Results The operations of the 2 patients were successful without any postoperative infection,the body returned to its normal.During the follow-up,the vagina mucosa was formed after vaginoplasty with acellular dermal repairing patch,which was very effective.For not using the vaginal mould according to the requirements, vagina adhension appeared in another patient after half year,but the vagina recovered normal soon by vagina distension,which can meet the requirements of sexual life.Conclusion The vaginoplasty with acellular dermal repairing patch and with peritoneum in the 2 patients is very effective,so it deserves to be recommended.

  12. 阴道镜下活检诊断宫颈上皮内瘤变678例%Colposcopic biopsy diagaosis of cervical intraepithelial neoplasia experience of 678 cases

    常宗龙; 杨霞

    2009-01-01

    Objective:The mirror appraising the electron vagina is worth to cervix lesion diagnose.Methods:678 example patients outpatient service does a vagina in FEB,2008 in MAY,2006~mirror mirror examining,checking a vagina go over has an image;Abnormal person,draws materials under the mirror,gives to pathological mechanism go over directly in the vagina,electron vagina mirror the image makes a definite diagnosis with neck of uterus microanatomy diagnose collation analysis,with pathological mechanism result action standard.Results:Patient of this group inspects up out the chronic cervicitis 85.99%, CIN11.50%,original place cancer 1.92%,infiltrates cancer 0.59%.Mirror infiltrating the cancer vagina the image is that the blood vessel is abnormal mainly,original place cancer vagina mirror visible image acetic acid white epithellum,major partners the shape blood vessei,heterotype blood vessel,mosaic and floccosoids wait a little bit;CIN acetic acid white maximum appears on epithelium,the shape blood vessel,heterotype blood vessel,rnosaic and floccosoids take second place;The chronic cervicitis gives first place to no representative shape blood vessel China and acetic acid white epithelium.Conclusion:Vagina mirror means examining importance reproducing road lesion under being early phase diagnose and treat.%目的:评价电子阴道镜对子宫颈病变的诊断价值.方法:2006年2月~2008年5月678例患者门诊行阴道镜检查,对阴道镜检查有图像异常者,直接在阴道镜下取材,送病理检查.电子阴道镜图像与宫颈组织学诊断对照分析,以病理结果作为确诊标准.结果:本组检出慢性宫颈炎85.99%,CIN11.50%,原位癌1.92%,浸润癌0.59%.浸润癌阴道镜图像主要是血管异常,原位癌阴道镜图像可见醋酸白色上皮,多数伴有点状血管、异型血管、镶嵌和白斑等;CIN醋酸白色上皮出现最多,点状血管、异型血管、镶嵌和白斑次之;慢性宫颈炎以不典型点状血管和醋酸白色

  13. Successful Delivery of Twin Pregnancy in Class U3b/C2/V1 Uterus by Bilateral Caesarean Section after Spontaneous Conception

    Yasmine El-Masry

    2015-01-01

    Full Text Available A case of a 19-year-old female with class U3b/C2/V1 uterus conceived a twin pregnancy with a fetus in each horn after spontaneous conception. She referred to our department with presentation of premature rupture of membranes, with a history of cesarean delivery of a single full term living fetus a year and a half before this delivery. Examination revealed two completely separate uterine horns with a fetus in each horn, two distinct externally rounded cervices, and a single vagina with a short nonobstructing vaginal septum in the upper part of the vagina. And as the appropriate mode of delivery is still unclear, each case should be managed as the condition requires, and in our case urgent bilateral caesarean sections were performed.

  14. Concomitant Imperforate Hymen and Transverse Vaginal Septum Complicated with Pyocolpos and Abdominovaginal Fistula

    Berna Dilbaz

    2014-01-01

    Full Text Available A 13-year-old patient with a complaint of worsening lower abdominal pain during the past 4 months was admitted to the emergency department. An abdominopelvic ultrasound scan revealed a distended uterocervical cavity suggestive of hematometrocolpos. Imperforate hymen was observed on examination of the external genitalia. MRI scan revealed an air-fluid level representing pyometrocolpos within a distended vagina. Posterior vaginal extraperitoneal leakage as the sign of a fistula between the vagina and the rectovaginal space was detected. Although laparoscopic approach was planned, malodorous pus expelled after the insertion of the Veress needle, it was decided to proceed to laparotomy. Pus with peritoneal microabscess formations was observed at laparotomy. The imperforate hymen and TVS were excised vaginally. A more complex anomaly should be suspected in cases with hematometra and concomitant imperforated hymen without any bulging and thorough evaluation using radiological imaging techniques should be performed before surgical approach.

  15. [The characteristic of biocenosis of urogenital tract in women].

    Andosova, L D; Kontorshchikova, K N; Kachalina, O V; Belov, A V; Gonova, E S; Kudel'kina, S Iu

    2013-01-01

    The article deals with the study of characteristics of biocenosis of urogenital tract in women of reproductive age with using of "Femoflor" test. The scrapings of posterolateral wall of vagina were analyzed using the technique of real-time polymerase chain reaction using the reagents "Femoflor". The complex evaluation of urogenital biota identified three main types of biocenosis of vagina: type I--normocenosis (n = 50 or 11.5%): type II--mild dysbiosis (n = 88 or 21%); type III--marked dysbiosis (n = 133 or 30.6%). In the structure of alterations of biocenosis of urogenital tract the main role play the anaerobic bacteria with involvement of candida, ureoplasma and mcoplasma. PMID:23807998

  16. Large vesico-vaginal fistula caused by a foreign body.

    Massinde, An; Kihunrwa, A

    2013-07-01

    Foreign body is a rare cause of vesico-vaginal fistula most often reported in developed countries. In developing countries obstructed labor is the commonest cause of fistula. A nulliparous 19-year-old female presented with a 3-week history of a foreign body in the vagina causing urinary incontinence and offensive vaginal discharge. Her guardian allegedly inserted the foreign body after she refused a pre-arranged marriage. A plastic container was removed from the vagina under general anesthesia. A large vesico-vaginal fistula was discovered, which was successfully surgically repaired. We recommend urgent removal of the foreign body, preferably under general anesthesia. However, if the history or physical examination reveals prolonged exposure, repair of the fistula should be delayed to allow for adequate debridement in order to prevent any life-threatening complications. PMID:24116334

  17. Surgical repair of rectovaginal fistula using gracilis muscular flap. A case report

    Inoue, Yasuhiro; Ooi, Masataka; Takeuchi, Kenji; Honzumi, Makoto [Nabari City Hospital, Mie (Japan); Fukunishi, Shigeji

    1999-07-01

    A 78 year-old female suffered from vaginal discharge of flatus and stool for 20 years after the radiation therapy for cervical cancer. Digital and endoscopic examination of the rectum and the vagina disclosed a large, short rectovaginal fistula at the level of the cervix. Since laparotomy and low anterior resection of the rectum were impossible, a perineal approach was adopted. After perineal skin incision, the fistula was resected and the defects of the rectum and the vagina were closed. Gracilis muscular flap was anchored between the two closures. Though the closure of the rectal side was torn, her postoperative course was uneventful. Endoscopic examination 24 days after the operation confirmed healing of the dehiscence. The results verified the usefulness of the perineal approach using the gracilis muscular flap as an alternative method to low anterior resection for troublesome radiation induced rectovaginal fistula. (author)

  18. [Female homicides involving deep injuries to sexual organs].

    Konopka, Tomasz; Woźniak, Krzysztof; Kunz, Jerzy; Fraczek, Dagna; Kozioł, Joanna

    2009-01-01

    In a search for motives that drive perpetrators of sexual homicides who perforate the vagina of a victim, an analysis was performed of such cases referred to the Krakow Department of Forensic Medicine. In the period 1981-2006, nine cases of this type were examined. In one instance, a forensic sexologist found evidence of sadism; similar observations were made in another three cases, where no perpetrator was determined. In four cases, in the course of sexual practices termed fisting, the perpetrator tore the vagina with his hand and inflicted extensive injuries within the abdominal cavity. In three of these cases, the intercourse was consensual, with the victim deeply intoxicated, while in the fourth instance, an inebriated perpetrator took advantage of the victim's infirmity. In a single case, vaginal tears were an effect of acute alcohol psychosis in the offender. PMID:20073256

  19. [Vaginal eviscentration with secondary strangulation of small bowel].

    Gembal, Piotr; Grzegorczyk, Wiesław; Grabowski, Bogumił; Milik, Krzysztof; Pajak, Marek; Bielecki, Krzysztof

    2007-01-01

    A case of 81 year old patient with eviscentration through vagina with a strangulation of small bowel was described. The woman was treated gynecologically and underwent surgery previously. The eviscentration occurred 21 months after last surgery and was connected with high abdominal pressure during defecation. Woman was qualified to an urgent laparotomy, and the hole about 15 mm length in vaginal posterior vault was found. Through the hole passed small bowel which was strangulated. The bowel was removed to the abdominal cavity and during its control no necrosis was found. The color and vascularity return to normal and right peristaltic was noticed. The hole in parietal peritoneum was closed by a continuous suture. The hole in vagina was also closed by the continuous suture from the perineal side. Woman in good general condition was discharged from hospital in the 13th day after surgery. PMID:18540188

  20. Una especie nueva de Smicridea de la Argentina (Trichoptera: Hydropsychidae A new species of Smicridea from Argentina (Trichoptera: Hydropsychidae

    Julieta V. Sganga

    2005-12-01

    Full Text Available RESUMEN. Se describen el macho y la hembra de una especie nueva de Smicridea (Rhyacophylax Müller (Hydropsychidae: Smicrideinae, recolectados cerca del Parque Nacional El Palmar, provincia de Entre Ríos, Argentina. Los machos se caracterizan por la presencia de tres puntas en el ápice del falo, una dorsal y dos laterales, y dos ganchos internos. La hembras se distinguen fácilmente por las características de la vagina y de la placa interna.ABSTRACT. The male and the female of a new species of Smicridea (Rhyacophylax Müller (Hydropsychidae: Smicrideinae collected near by El Palmar National Park, Entre Ríos Province, Argentina, are described. The males of this species are characterized by the presence of three points at the apex of the phallus, one dorsal and two lateral, and two lateral internal hooks. The females are easily distinguished by the characteristics of the vagina and the internal plate.

  1. MR-colpocystorectography. A new dynamic method for assessing pelvic floor descent and prolapse in women

    Introduction of a new method for the dynamic evaluation of genital prolapse by using fast magnetic resonance imaging. Dynamic fast magnetic resonance imaging with pelvic floor contraction, relaxation and straining manoeuvres were performed with volunteers and patients presenting with pelvic descent. The urethra, bladder, vagina and rectum were opacified by using a water of MagnevistR enteral solution. Delineation and movement of the urethra, bladder, uterus, vagina, rectum and small bowel can be shown in a reliable manner. In comparison to dynamic fluoroscopy an equal or superior diagnosis has been achieved in all cases. In comparison to dynamic fluoroscopy MR-Colpocystorectography is a promising new method in assessing pelvic floor descent and prolapse in women. Further studies will have to focus on standardisation and clinical implication. (orig.)

  2. Mayer-Rokitansky-Kuster-Hauser Syndrome with hyperprolactinemia

    Mayer-Rokitansky-Kuster-Hauser Syndrome in association with hyperprolactinemia is very rare. An 18-year-old Saudi single, virgin female was accompanied by her mother seeking medical advice regarding absent menses. She had normal breasts, normal axillary and pubic hair, normal vulva, urethra and labial folds, however, the vagina was blind, approximately 2 cm length. Pelvic magnetic resonance imaging showed normal appearing ovaries, a small uterus and small cervix and vagina. Investigations showed initial high serum prolactin of 1,517mIU/L. Cranial MRI was normal. The patient was diagnosed as mullerian hypoplasia class I American Fertility Society. After an extensive literature search, we present a unique case of concomitant occurrence of MRKH, in the form of mullerian hypoplasia and hyperprolactinemia. (author)

  3. The human vaginal bacterial biota and bacterial vaginosis.

    Srinivasan, Sujatha; Fredricks, David N

    2008-01-01

    The bacterial biota of the human vagina can have a profound impact on the health of women and their neonates. Changes in the vaginal microbiota have been associated with several adverse health outcomes including premature birth, pelvic inflammatory disease, and acquisition of HIV infection. Cultivation-independent molecular methods have provided new insights regarding bacterial diversity in this important niche, particularly in women with the common condition bacterial vaginosis (BV). PCR methods have shown that women with BV have complex communities of vaginal bacteria that include many fastidious species, particularly from the phyla Bacteroidetes and Actinobacteria. Healthy women are mostly colonized with lactobacilli such as Lactobacillus crispatus, Lactobacillus jensenii, and Lactobacillus iners, though a variety of other bacteria may be present. The microbiology of BV is heterogeneous. The presence of Gardnerella vaginalis and Atopobium vaginae coating the vaginal epithelium in some subjects with BV suggests that biofilms may contribute to this condition. PMID:19282975

  4. The McKusick-Kaufman hydrometrocolpos-polydactyly syndrome: A rare case report

    Swapnil P Yewalkar

    2013-01-01

    Full Text Available A combination of hydrometrocolpos, polydactyly, and cardiac anomlies is the cardinal feature of McKusick-Kaufman syndrome. Neonatal hydrometrocolpos is rare Mullerian duct anomaly caused by obstruction of the vagina. There is an accumulation of mucus secretions proximal to the obstruction. The secretions are secondary to intrauterine and postnatal stimulation of uterine and cervical glands by maternal estrogens. Here, we report a case of 1-day-old neonate who presented with abdominal distension. Ultrasound and computed tomography findings revealed a large abdominopelvic cystic mass posterior to the urinary bladder. Other associated findings were polydactyly and bilateral hydronephosis. Laparotomy confirmed the findings of hydrometrocolpos caused by stenosis/atresia of lower vagina.

  5. Vaginal Smear TNF-alpha, IL18, TLR4, and GATA3 mRNA Levels Correlate with Local Inflammation

    Olga Bourmenskaya

    2014-12-01

    Full Text Available Background: A molecular approach to estimation of local inflammatory response associated with dysbiotic conditions of the vagina is reported. This approach is based on immune response gene transcription levels measured by qPCR assay. Methods and Results: qPCR analysis of 24 immune response gene transcripts in vaginal smears was performed for 215 women with vaginitis and 95 healthy controls. The data were sorted by comparison to local inflammatory response profiles assessed by conventional methods. The local inflammatory response in the vagina is found to correlate with TNF-alpha, IL18, TLR4, and GATA3 transcript levels. Sensitivity and specificity of the approach, as validated in accordance with conventional clinical examination results, are 94.9% and 93.7%, respectively. Conclusions: The noninvasive diagnostic approach to vaginal pathology based solely on its molecular characterization may prove to be clinically relevant.

  6. The effect of incubation time on capacitation and acrosome reaction of in vitro ovine spermatozoa

    J Wattimena

    2012-01-01

    The aim of this research was to know the effect of incubation time on capacitation and acrosome reaction of in vitro ovine spermatozoa. Twelve ejaculates from two Garut sheep were collected using artificial vagina and then evaluated macro and microscopically. After semen washing (centrifugation method), semen was diluted in Brackett and Oliphant (BO) medium and then incubated during 6 hours in incubator CO2, temperature 38.5ºC. Evaluation of capacitation and acrosome reaction was conducted on...

  7. Evaluation of Reuterin Production in Urogenital Probiotic Lactobacillus reuteri RC-14▿

    Cadieux, Peter; Wind, Anette; Sommer, Philip; Schaefer, Laura; Crowley, Kate; Britton, Robert A.; Reid, Gregor

    2008-01-01

    Classified as a distinct species in 1980, Lactobacillus reuteri strains have been used in probiotic formulations for intestinal and urogenital applications. In the former, the primary mechanism of action of L. reuteri SD2112 (ATCC 55730) has been purported to be its ability to produce the antibiotic 3-hydroxypropionaldehyde (3-HPA), also known as reuterin. In the vagina, it has been postulated that probiotic Lactobacillus reuteri RC-14 does not require reuterin production but mediates a resto...

  8. Female form of persistent mullerian duct syndrome: Rare entity

    Shailesh Solanki

    2015-01-01

    Full Text Available Persistent Mullerian duct syndrome (PMDS is a rare form of Disorder of sex development in which Mullerian duct derivatives (fallopian tubes, uterus and the proximal vagina are present in an otherwise normally differentiated 46 XY male. In the majority of cases, PMDS is a surprise finding either during orchidopexy or during inguinal hernia repair. We report a case of 4 year child with female type (Type III PMDS. We are discussing the presentation, management and review of the literature.

  9. WOMEN FACING HEAVY VAGINAL DISCHARGE (LEUCORRHEA) BY VIRTUE OF UNHEALTHY LIFE STYLE

    Somia Gul; Hina Qamar; Wardha Jawaid; Urooj Bukhari; Yumna Javed

    2013-01-01

    Leucorrhea also spelled leucorrhoea, flow of a whitish, yellowish, or greenish discharge from the vagina of the female that may be normal or that may be a sign of infection. It is mucous discharge which represents desquamation of vaginal epithelial cells because of the effects of estrogen on the vaginal mucosa. It is important to distinguish leucorrhea from pathologic discharge. Leucorrhea usually does not cause irritation but some adolescents worry that it may represent an infection. A total...

  10. Relative Roles of the Epithelial and Stromal Tissue Compartment(s) in Mediating the Actions of Relaxin and Estrogen on Cell Proliferation and Apoptosis in the Mouse Lower Reproductive Tract

    Yao, LiJuan; Agoulnik, Alexander I.; Cooke, Paul S.; Meling, Daryl D.; Sherwood, O. David

    2009-01-01

    Relaxin and estrogen are secreted by the ovary during the second half of pregnancy in rats and mice. Relaxin promotes marked growth of the lower reproductive tract in both species. Relaxin promotes accumulation of epithelial and stromal cells in the cervix and vagina by both stimulating cell proliferation and inhibiting apoptosis. Estrogen acting through estrogen receptor α (ERα) plays an essential permissive role in relaxin’s actions. A fundamental step toward understanding the actions of re...

  11. Conditional Deletion of the Relaxin Receptor Gene in Cells of Smooth Muscle Lineage Affects Lower Reproductive Tract in Pregnant Mice1

    Kaftanovskaya, Elena M.; Huang, Zaohua; Lopez, Carolina; Conrad, Kirk; Agoulnik, Alexander I.

    2015-01-01

    Relaxin hormone secreted into the circulation during pregnancy was discovered through its effects on pubic symphysis relaxation and parturition. Genetic inactivation of the relaxin gene or its cognate relaxin family peptide receptor 1 (RXFP1) in mice caused failure of parturition and mammary nipple enlargement, as well as increased collagen fiber density in the cervix and vagina. However, the relaxin effect on discrete cells and tissues has yet to be determined. Using transgenic mice with a k...

  12. {sup 18}F-Fluorodeoxyglucose PET/CT in a Patient with Esophageal and Genital Leiomyomatosis

    An, Young Sil; Kim, Deog Yoon [Kyung Hee University, Seoul (Korea, Republic of)

    2009-12-15

    Diffuse esophageal leiomyomatosis is a rare benign tumor, which can be associated with leiomyoma in female genital tracts involving the uterus, vagina, and vulva. Alport syndrome, an inherited disorder that includes the kidneys, eyes, and sensorineural hearing loss, is also rarely associated with these multiple leiomyomatosis. In our case, {sup 18}F-fluoroseoxyglucose positron emission tomography/ computed tomography was used to distinguish esophageal and genital leiomyomatosis from malignant masses.

  13. 小切口保留完整粘膜阴道紧缩术%Vaginal tightening surgery of mini-incision and complete vaginal mucosa

    刘晓夏; 何俭; 殷剑波

    2012-01-01

    Objective To investigate the best surgical method on the vaginal relaxation. Methods The outside 1/3 segments of vagina and aditus vaginae were tighten by the operation with mini -incision.complete vaginal mucosa and suture polyptychial. Results This method was applied to 105 cases successfully. Follow up six months to three years, all patients were satisfied to the results. Conclusion On the basis of tightening the muscles, this method is more focused on the tightening to the outside 1/3 segments of vagina and aditus vaginae. The method with mini-incision and complete vaginal mucosa is more meet the physical characteristics, improve the quality of sex life and has an exact effect.%目的:探究阴道缩窄的最佳手术方式.方法:采用小切口并保留完整阴道粘膜的术式,对阴道后壁多层缝合,使阴道外1/3及阴道口得以收紧.结果:将此法应用于105例阴道松弛患者,手术全部成功,术后随访0.5~3年,效果满意.结论:小切口保留完整粘膜阴道紧缩术在收紧阴道肌肉的基础上,着重于对阴道外1/3及阴道口的收紧,更符合生理特性,提高性生活质量,效果确切.

  14. Complex Genital Malformation in a Female with Congenital Adrenal Hyperplasia: Evaluation with Magnetic Resonance Imaging

    Klessen, C.; Asbach, P.; Hein, P. A.; Beyersdorff, D.; Hamm, B.; Taupitz, M. [Humboldt-Univ. of Berlin, Campus Charite Mitte (Germany). Dept. of Radiology

    2005-12-01

    This is a case of complex genital malformation in a young patient with congenital adrenal hyperplasia. The magnetic resonance imaging (MRI) findings included ostium of the vagina into the urethra (common urogenital opening), prostate-like tissue surrounding the urethra, and hyperplasia of the left adrenal gland. The report provides information on the clinical findings, the MRI examination, including the applied sequences and the MR findings, and gives an overview of the disease pattern and its frequency of occurrence.

  15. Dynamic MR Imaging of the Pelvic Floor:Technical Considerations and Image Analysis

    2011-01-01

    @@ The pelvic floor is a complex anatomic and functional unit of multiple muscle layers, fascia and ligaments.In clinical routine, a simple anatomic concept of the female pelvic floor has gained acceptance.Especially for treatment planning,the female pelvic floor may be separated into three functional compartments:.the anterior compartment (bladder and urethra), the middle compartment (vagina,cervix,uterus,and adnexa), and the posterior compartment (anus and rectum).

  16. Lactobacillus crispatus as biomarker of the healthy vaginal tract.

    Lepargneur, Jean-Pierre

    2016-08-01

    Decades of research have shown that the lactobacilli inhabiting the human vagina are the first line of defense in the female urogenital and reproductive tracts. In healthy cervicovaginal microbiota, Lactobacillus crispatus is prevalent and beneficial with production of copious amounts of lactic acid potent broad spectrum bactericide virucide and immunomodulator. Future and preventic approaches may need to include probiotics, prebiotics also have the potential to optimize and restore the vaginal ecosystem. PMID:27492695

  17. A Giant Gartner Duct Cyst Originating from the Uterine Cervix and Adjacent Myometrium: A Case Report

    Kim, Eun Hui; Hwang, Seong Su; Park, Soo Youn [Catholic University, Seoul (Korea, Republic of)

    2008-11-15

    Gartner duct cysts are relatively common congenital cysts in the anterolateral wall of the vagina. Most are small (less than 2 cm) and asymptomatic, but larger cysts may cause problems. We report a rare case of a giant Gartner duct cyst (7 cm) originating from the right lateral portion of the uterine cervix and adjacent myometrium. It appeared as an exophytic multiseptated cystic mass containing different density fluids on CT

  18. 太具挑战性了:倾听"V"的独白

    卜卫

    2002-01-01

    @@ 不久前一个细雨蒙蒙的夜晚,300多名观众涌进上海一家国际俱乐部,观看一出用英语演出的戏剧,剧名是"Vagina Monologues"(阴道独白).我暗暗吃惊,"阴道"会有什么样的独白?

  19. Dystopic dysplastic kidney with ectopic ureter: improved localization by fusion of MR urography and {sup 99m}Tc-DMSA SPECT datasets

    Kreissl, Michael C.; Lorenz, Reinhard [University Clinic Wuerzburg, Clinic and Polyclinic of Nuclear Medicine, Wuerzburg (Germany); Ohnheiser, Gerd [University Clinic Wuerzburg, Zentrum Operative Medizin, Clinic and Polyclinic of Urology, Wuerzburg (Germany); Darge, Kassa [University Clinic Wuerzburg, Department of Paediatric Radiology, Institute of Radiodiagnosis, Wuerzburg (Germany)

    2008-02-15

    We report a 12-year-old girl with a long history of constant urinary dribbling and apparently only a left kidney. Using a multimodality approach involving the fusion of MR urography and {sup 99m}Tc-dimercaptosuccinic acid (DMSA) SPECT datasets, it was finally possible to exactly localize the very small dystopic, dysplastic right kidney and its ectopic ureter draining into the vagina. (orig.)

  20. 自体口腔黏膜微粒移植再造阴道%Reconstructive vaginoplasty with autologous transplantation of minced oral mucus membrane

    白晓东; 柳晓杰; 刘贤华; 王佳哲; 马丽; 林志龙

    2012-01-01

    Objective To explore ihe clinical fealure of vaginal reconslruclion by aulologous Iransplanla-lion of minced oral mucus membrane. Methods From July 2010 to Janurary 2012, lolally 30 palienls wilh congenilal absence of ihe vagina were received in our department and Irealed by aulologous Iransplanlalion of minced oral mucus membrane for reconslruclive vaginoplasly. Afler that, the reconstructed vagina was casled by model for half year. Results The vaginoplasly of all 30 cases were successful. Afler 10 months follow-up posl-operalively in 23 cases, good configuration of vulvae and vagina were received. Conclusion Vaginal reconslruclion by aulologous Iransplanlalion of minced oral mucus membrane could be a basic consideration for congenilal absence of the vagina, and il is worth spreading in clinic.%目的 探讨自体口腔黏膜微粒移植在阴道再造中的应用.方法 自2010年7月至2012年1月,我科收治30例先天性无阴道患者,采用口腔黏膜微粒移植再造阴道,模具支撑阴道成形.结果 本组30例患者手术全部成功,术后对23例患者随访10个月,外部和阴道形状满意.结论 自体口腔黏膜微粒移植再造阴道安全、有效,值得临床推广.

  1. Determining the Stage of the Estrous Cycle in Female Mice by Vaginal Smear.

    Gonzalez, Gabriel

    2016-01-01

    Female mice undergo a 3- to 5-d, hormonally controlled estrous cycle. The estrous cycle is divided into different stages, including diestrus, proestrus, estrus, and metestrus. These stages can easily be determined by examining washes or cell smears of the vagina. Determining the stage of the estrous cycle may be important for setting up matings, identifying receptive females for artificial insemination, and analyzing phenotypes of the female reproductive tract. PMID:27480723

  2. Laparoscopic rectosigmoid colpopoiesis as treatment for a patient with Mayer-Rokitansky-Kuster-Hauser syndrome

    万小平; 席晓薇; 严沁

    2003-01-01

    @@ The most common presentation of congenital absence of the vagina is known as Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome.1,2 Several procedures, invasive and noninvasive, have been used for the creation of a neovagina. A technique frequently used for this purpose in China over the last 20 years is rectosigmoid colpopoiesis. Here we report a successful rectosigmoid colpopoiesis done laparoscopically in a patient with MRKH syndrome.

  3. Animated Asphalt

    Paldam, Camilla Skovbjerg

    2015-01-01

    In What do pictures want? The lives and loves of images (2005) J. W. T. Mitchell writes about pictures as “vital signs”, not signs for living things, but signs as living things (Mitchell 6). With a notion from the German art historian and media theorist Hans Belting this symbolic act can be calle...... answer to that, but the question will lead to a discussion of representations of women’s desire, exemplified by discursive and visual representations of the vagina....

  4. Comment je traite...un uterus didelphe associe a un hemi-vagin borgne

    Loumaye, F.; Cheruy, Charlotte; Cristinelli, S.; Foidart, Jean-Michel; Nisolle, Michelle

    2007-01-01

    Didelphys uterus with imperforated obstructed hemivagina is a rare condition. Most often, it is diagnosed a few months after the menarche. Hematocolpos, hematometria and sometimes hematosalpinx are responsible for pelvic pain and dysmenorrhea. Symptoms can be delayed when a fistulisation from the hematocolpos to permeable contralateral vagina is present. Sometimes, diagnosis is not made before adulthood during an infection of the hematocolpos. Useful additional exams include pelvic ultrasound...

  5. Uterus didelphys with partial vaginal septum and distal vaginal agenesis: an unusual anomaly

    Complex malformations of female genital tract are not so common. Their correct identification is of paramount importance for appropriate management. A thorough knowledge of embryology, pre-operative imaging with MRI and examination under anaesthesia is essential to identify accurately the constellation of anomalies and to plan appropriate management. This case reports the coexistence of Mullerian abnormality with vaginal agenesis in an 18 years old girl which was managed by dissecting the lower half of vagina and pull-through vaginoplasty. (author)

  6. Uterine Carcinosarcoma in a Patient with Didelphys Uterus

    Iavazzo, C.; F. Kokka; Sahdev, A; Singh, N.; Reynolds, K.

    2013-01-01

    Background. Didelphys uterus is a noncommon finding in women. Till now, few cases with benign mesenchymal tumors in patients with didelphys uterus are described. We present a case of a patient with carcinosarcoma arising in a didelphys uterus. Case. A 73-year-old patient presented with profuse watery postmenopausal bleeding. On examination under anesthesia, left and right cervixes were identified. Tumor extended from the left cervix into the lower third of the vagina and was adherent to the r...

  7. Congenital pouch colon in a girl associated with bilateral atresia of cervix uteri and uterus didelphys

    Rajiv Chadha; Manju Puri; Rahul Saxena; Surendrakumar Agarwala; Archana Puri; Subhasis Roy Choudhury

    2013-01-01

    This report describes a girl with congenital pouch colon (CPC), uterus didelphys with septate vagina, and a cloacal anomaly. The girl underwent cloacal reconstruction at the age of 15 months. Subsequently, at puberty, the child had primary amenorrhea with severe cyclic abdominal pain due to endometriosis of both the uteruses and adnexal cysts with hematometra and hematosalpinx. Laparotomy with removal of both uteri and the left fallopian tube was performed. Both uteri had atresia of the cervi...

  8. Recurrent preeclampsia and breech presentation in term pregnancy: the case of didelphic uterus

    Temesgen Tilahun Bekabil

    2015-01-01

    Uterine didelphys represents a uterine malformation where the uterus is present as a paired organ. It is characterized by the presence of two endometrial cavities, each with a uterine cervix, and often a double or single vagina as well. Uterine didelphys, like other uterine malformations, is often asymptomatic and therefore remain unrecognized. The didelphic uterus has a poor reproductive outcome with a 20-30% chance of carrying pregnancy to term. I report a case of successful pregnancy in th...

  9. OHVIRA: Uterus didelphys, blind hemivagina and ipsilateral renal agenesis: Advantage MRI

    Bajaj, Sunil K.; Ritu Misra; Thukral, Brij B; Rohini Gupta

    2012-01-01

    We present here a case of an uncommon complex uterine anomaly - Obstructed HemiVagina with Ipsilateral Renal Agenesis (OHVIRA), also known as Herlyn-Werner-Wunderlich syndrome in a 14-year-old girl along with sonographic (trans-abdominal and trans labial), and MRI findings. The patient underwent surgery wherein imaging findings were confirmed. An MRI has proved to be of great help in correct diagnosis avoiding surgical interventions/ laparoscopy, which were needed in past to diagnose this rar...

  10. [Study of vaginal and intestinal microflora of women in the prenatal period and its correction in dysbacteriosis].

    Podgorskiĭ, V S; Liaskovskiĭ, T M; Kovalenko, N K; Oleshchenko, L T

    2006-01-01

    A comparative research of the structure of vaginal and intestinal microflora in norm and at kidney pathologies in women in the prenatal period was carried out. At physiologically normal course of pregnancy microbiocenosis of vagina and intestine does not contain pathogenic and conditional-pathogenic microorganisms. Lactic acid bacteria are fixed within the limits of 10(5)-10(8) CFU/1 ml in the vagina secretion and 10(7)-10(8) CFU/1 g in the intestine content. The spore microorganisms have completely disappeared in vaginal biocenosis of women with pyelonephritis after pharmacotherapy; and colibacterias has disappeared in 62% of women. Quantity of lactic acid bacteria has also decreased. Quantity of E. coli (10(8)- 10(9)) CFU/g, sporous microorganisms (10(3)-10(4)) CFU/g and yeast (10(4)-10(5)) CFU/g has considerably increased in the content of intestine. Lactic acid bacteria in content of the vagina are presented by: Lactobacillus acidophilus, L. plantarum, L. fermentum, L. vaginalis; in content of the intestine--L. plantarum and L. fermentum. All the isolated strains of lactobacilli are resistant to metrogyl and amphotericin, 87%--to cephoxitine, cypropfloxacine. Twenty three of 24 strains of lactic acid bacteria--antagonists of pathogenic microflora have shown adhesion to vaginal epthelium. The degree of adhesive activity depends on the strain and genus specificity of cultures. The highest index of adhesiveness in indicated in Enterococcus faecium (5.82 - 7.62) and Streptococcus salivarius subsp. thermophilus (2.74 - 6.40) strains. The screening of strains has been performed, which suppress growth of gas-producing microflora. The strain of Lactobacillus plantarum 200D proved to be the most active one. A complex of cultures of the lactic bacteria providing normalization of microbial cenosis of the vagina in women in the prenatal period has been selected as based on the data obtained. The biotechnology of production of vaginal suppositories is developed. PMID

  11. FEMALE URETHRA – ANATOMO-CLINICAL IMPLICATIONS

    C. Zanoschi; R. Moldovanu

    2006-01-01

    Urethra represents the last segment of the urinary tract. We present a comprehensive account of the female urethral anatomy, including its component structures, neurovascular supply, relationship to adjacent structures (the vagina, bladder and vestibular glands, and connective tissue supports) and histology. These data are important because the distal segment of the female urethra is implicated in the mechanism of urinary continence (female stress urinary incontinence is thought to result f...

  12. Transvaginal Appendectomy: A Systematic Review

    Mehmet Ali Yagci; Cuneyt Kayaalp

    2014-01-01

    Background. Natural orifice transluminal endoscopic surgery (NOTES) is a new approach that allows minimal invasive surgery through the mouth, anus, or vagina. Objective. To summarize the recent clinical appraisal, feasibility, complications, and limitations of transvaginal appendectomy for humans and outline the techniques. Data Sources. PubMed/MEDLINE, Cochrane, Google-Scholar, EBSCO, clinicaltrials.gov and congress abstracts, were searched. Study Selection. All related reports were included...

  13. Transvaginal Laparoscopic Appendectomy Simultaneously with Vaginal Hysterectomy: Initial Experience of 10 Cases

    Tian, Yu; Wu, Shuo-Dong; Chen, Ying-Han; Wang, Dan-Bo

    2014-01-01

    Background Natural orifice transluminal endoscopic surgery (NOTES) involves the introduction of instruments through a natural orifice into the peritoneal cavity to perform surgical interventions. The vagina is the most widely used approach to NOTES. We report the utilization of the vaginal opening at the time of vaginal hysterectomy as a natural orifice for laparoscopic appendectomy. Material/Methods We reviewed cases of 10 patients with chronic appendicitis who underwent transvaginal laparos...

  14. State-of-the-art of infections produced by human papillomavirus.

    Julio César Reina; Nubia Muñoz; Gloria Inés Sánchez

    2009-01-01

    Anogenital human papillomavirus infection is the most frequent sexually transmitted disease. Around one hundred genotypes have been identified in humans, and 40 infect the genitalia and anal regions. Fifteen genotypes, classified as high-risk HPVs, are the necessary cause of cervical cancer and have been involved as carcinogenic agents for cancer of the vulva, vagina, anus, penis, and oropharyngeal cavity. Low-risk HPVs are the causative agents of genital warts, and recurrent respiratory papi...

  15. THE ANALYSIS OF STATISTICAL DATA ON MALIGNANT NEOPLASMS ASSOCIATED WITH HUMAN P APILLOMAVIRUS

    A. A. Kostin; V. V. Starinskiy; Y. V. Samsonov; A. T. Asratov

    2016-01-01

    In this study of statistical data for the first time in Russia the analysis of the morbidity and mortality of patients with malignant neoplasms that may be associated with human papilloma virus (HPV) is performed: cervical cancer (cervical cancer), cancer of the vulva and vagina, cancer of penis, cancer of the rectum, anal canal and rectosigmoid junction cancer, cancer of the pharynx and larynx.

  16. Identification and H2O2 Production of Vaginal Lactobacilli from Pregnant Women at High Risk of Preterm Birth and Relation with Outcome

    Wilks, Mark; Wiggins, Rebecca; Whiley, Angela; Hennessy, Enid; Warwick, Simon; Porter, Helen; Corfield, Anthony; Millar, Michael

    2004-01-01

    Lactobacilli, principally the strains that are hydrogen peroxide (H2O2) producing, may have a protective effect against vaginal colonization by pathogenic species such as those that cause bacterial vaginosis. Previous reports have also suggested that H2O2-producing lactobacilli in the vagina may protect pregnant women against ascending infection of the chorioamniotic membranes and uterine cavity. We report the identification and H2O2 production of lactobacilli isolated from vaginal swabs coll...

  17. Oral Candida spp. colonization in human immunodeficiency virus-infected individuals

    D. V. Moris; Melhem, M. S. C.; Martins, M. A.; Mendes, R P

    2008-01-01

    Several yeast species of Candida genus can colonize the skin as well as the mucous membrane of the vagina and the digestive tract for short or long periods. Depending on the host's immunological state and the yeast's virulence, colonization can become an infection, invading the colonized tissues and also disseminating. AIDS is characterized by the host's intensive and progressive immunodepression which manifests as diverse symptoms, mainly lesions in the mouth. Oral candidiasis is the most pr...

  18. Maternal-infant separation impedes changes in feeding behavior during estrous cycle of rats

    Iwasaki, Shinichi; Inoue, Koki

    2015-01-01

    Traumatic and stressful events during childhood are associated with the development of eating disorders. We conducted an animal study to test if association stress in childhood affects ingestive behavior later in life by using female rats that have an adjusted estrous cycle. First, electrical impedance of the vagina was conducted to test estrous cycle adjustment. Second, the effects of 6 h per day maternal separation from birth to weaning, which models a psychologically stressful experience i...

  19. Is Procidentia a Distinct Disease? Comparison of Risk Factors

    Serdar Aydin

    2014-01-01

    Aim: Total prolapse%u2014in other words, procidentia%u2014refers to the complete eversion of the total length of the vagina. Age, pregnancy, delivery, previous pelvic surgery, and conditions that increase intra-abdominal pressure, such as chronic pulmonary disease, constipation, and obesity are risk factors for pelvic organ prolapse. This study aims to assess the incidence of anterior, posterior, apical, and total prolapse and to determine differences in the risk factors for different vaginal...

  20. Studies on nerve terminations in human mucosa and skin

    Hilliges, Marita

    1997-01-01

    - In spite of their accessibility and important sensory function,the nervous tissue components of human oral and vaginal mucosa and skin have beensubject to very few, if any, systematic investigations. Studies on the innervationof oral tissues have mainly focused on the dental pulp, the periodontium and thegingiva, probably because of specific clinical interest, thus largely neglectingthe mucosa. Genital studies comprise only in a few cases the vagina and when thevagina is i...

  1. Ovarian radiation dose during dynamic cystourethrography using videorecording and photofluorography

    Westby, M.; Sandbu, J.; Jahren, R.; Asmussen, M.

    The ovarian radiation dose in dynamic cystourethrography was estimated by thermoluminescence dosimetry in a phantom and in 26 patients. The urodynamic examination technique was standardized and included fluoroscopy with videorecording and rapid sequence 100 mm fluorography. The examination was performed in the lateral position with dosimeters in the vagina, uterine cavity and rectum. The total dose in the midline was 13 mGy per examination, which compares with 12 mGy in urography.

  2. Ovarian radiation dose during dynamic cystourethrography using videorecording and photofluorography

    The ovarian radiation dose in dynamic cystourethrography was estimated by thermoluminescence dosimetry in a phantom and in 26 patients. The urodynamic examination technique was standardized and included fluoroscopy with videorecording and rapid sequence 100 mm fluorography. The examination was performed in the lateral position with dosimeters in the vagina, uterine cavity and rectum. The total dose in the midline was 13 mGy per examination, which compares with 12 mGy in urography. (orig.)

  3. A manifesto on the preservation of sexual function in women and girls with cancer

    Lindau, Stacy Tessler; Abramsohn, Emily M.; Matthews, Amber C.

    2015-01-01

    Malignancies that affect females who survive cancer commonly originate in, invade, and/or metastasize to the sexual organs, including the ovaries, uterine corpus, uterine cervix, vagina, vulva, fallopian tubes, anus, rectum, breast(s), and brain. Females comprise most of the population (in number and proportion) with cancers that directly affect the sexual organs. Most females in the age groups most commonly affected by cancer are sexually active in the year before diagnosis, which includes m...

  4. Fistule urogénitale obstétricale: a propos de deux observations en France [Obstetric vesicovaginal fistula: reporting two cases in France].

    Labarrère, Amandine; Gueye, Ameth; Ouaki, Frédéric; Pires, Christophe; Pierre, Fabrice; Fritel, Xavier

    2011-01-01

    Obstetric vesicovaginal fistula is nowadays rare in developed countries. We are reporting two cases of patients with obstetric vesicovaginal fistula that occurred after operative vaginal deliveries performed in a French hospital. Early postpartum symptoms were vaginal urine leakage and infectious syndrome. The fistula has been cured by vaginal surgery one case and combined (laparotomy and vagina surgery) in the other case. Patients were totally healed a few months following the surgery.

  5. [Obstetric vesicovaginal fistula: reporting two cases in France].

    Labarrère, A; Gueye, A; Ouaki, F; Pires, C; Pierre, F; Fritel, X

    2011-05-01

    Obstetric vesicovaginal fistula is nowadays rare in developed countries. We are reporting two cases of patients with obstetric vesicovaginal fistula that occurred after operative vaginal deliveries performed in a French hospital. Early postpartum symptoms were vaginal urine leakage and infectious syndrome. The fistula has been cured by vaginal surgery one case and combined (laparotomy and vagina surgery) in the other case. Patients were totally healed a few months following the surgery. PMID:21514873

  6. The Perinatal Microbiome and Pregnancy: Moving Beyond the Vaginal Microbiome

    Prince, Amanda L.; Chu, Derrick M.; Seferovic, Maxim D.; Antony, Kathleen M.; Ma, Jun; Aagaard, Kjersti M.

    2015-01-01

    The human microbiome, the collective genome of the microbial community that is on and within us, has recently been mapped. The initial characterization of healthy subjects has provided investigators with a reference population for interrogating the microbiome in metabolic, intestinal, and reproductive health and disease states. Although it is known that bacteria can colonize the vagina, recent metagenomic studies have shown that the vaginal microbiome varies among reproductive age women. Simi...

  7. Pharmacomicrobiomics: The Impact of Human Microbiome Variations on Systems Pharmacology and Personalized Therapeutics

    ElRakaiby, Marwa; Dutilh, Bas E.; Rizkallah, Mariam R; Boleij, Annemarie; Cole, Jason N; Aziz, Ramy K.

    2014-01-01

    The Human Microbiome Project (HMP) is a global initiative undertaken to identify and characterize the collection of human-associated microorganisms at multiple anatomic sites (skin, mouth, nose, colon, vagina), and to determine how intra-individual and inter-individual alterations in the microbiome influence human health, immunity, and different disease states. In this review article, we summarize the key findings and applications of the HMP that may impact pharmacology and personalized thera...

  8. Malformations in a cohort of 284 women with Mayer-Rokitansky-Küster-Hauser syndrome (MRKH

    Oppelt Patricia G

    2012-08-01

    Full Text Available Abstract Background The aim of this retrospective study was to describe the spectrum of genital and associated malformations in women with Mayer-Rokitansky-Küster-Hauser syndrome using evaluated diagnostic procedures and the Vagina Cervix Uterus Adnex – associated Malformation classification system (VCUAM. Methods 290 women with MRKH syndrome were clinically evaluated with using clinical examinations, abdominal and perineal/rectal ultrasound, MRI, and laparoscopy. Results Classification of female genital malformation according to the Vagina Cervix Uterus Adnex – associated Malformation classification system was possible in 284 women (97.9%. Complete atresia of Vagina (V5b and bilateral atresia of Cervix (C2b were found in 284 patients (100%. Uterus: bilateral rudimentary or a plastic uterine horns were found in 239 women (84.2%. Adnexa: normal Adnexa were found in 248 women (87.3%. Malformations: associated malformations were found in 126 of 282 evaluable women (44.7%, 84 women (29.6% had malformations of the renal system. Of 284 women with Mayer-Rokitansky-Küster-Hauser syndrome 212 women (74.7% could be classified as V5bC2bU4bA0. The most frequent classification was V5bC2bU4bA0M0 (46.8% diagnosed in 133 of 284 women. Conclusions Complete atresia of vagina and cervix were found in all patients, variable malformations were found with uterus and adnexa. A variety of associated malformations were present, predominantly of the renal system. It is therefore recommended that all patients with genital malformations should be evaluated for renal abnormalities.

  9. Rebuilding life: A journey through the lives of women who have endured and been treated for obstetric fistula in Tanzania

    Irani, Julia Noshir

    2012-01-01

    Introduction Obstetric fistula is a birthing injury which leaves a woman leaking urine and/or faeces from her vagina. This occurs when there is prolonged obstructed labour, and emergency obstetric care is unavailable. It disproportionately affects poor, uneducated women from rural areas and makes them even more marginalized after they have suffered the injury. The constant smell from leaking subjects them to rejection from society, they are unable to work, and are ashamed of their conditio...

  10. MUNGKINKAH PENIS DIPERBESAR

    Bambang Wasito

    2012-01-01

    A man frequently complains many matters on his sexual functions. Sometime people care with the penis diameter than the length. Here no physiological reason on diameter that influences sensation during coitus. Vagina can amazing and accomodating the present object to a size of one finger until a baby head. The size phallus is an attractive attentionas to increase the number of men who looking for penis enlargement, some men ask penis enlargement for functional reasons; nevertheless, the majori...

  11. Social and health reasons for lime juice vaginal douching among female sex workers in Borno State, Nigeria

    Mairiga, Abdulkarim G.; Kullima, Abubakar A.; Kawuwa, Mohammed B.

    2010-01-01

    Background: Vaginal douching with lime juice and other agents has been perceived to enhance sexual excitement through sensations of vaginal dryness, tightness or warmth, as well as prevent sexually transmitted infections and restore and tighten the vagina after delivery. Its effectiveness as a contraceptive has also been reported. However, the social and health reasons/consequences of such a practice have not been adequately documented in the communities of Borno State, Nigeria.Objectives: Th...

  12. Pogostnost bakterijske vaginoze in povezava s prezgodnjim porodom: Incidence of bacterial vaginosis and its relation to preterm delivery:

    Novak, Mojca; Prosen, Barbara

    1998-01-01

    Bacterial vaginosis is characterized by the presence of large amounts of anaerobic bacteria, Gardnerella vaginalis and Mycoplasma hominis in the vagina, where they replace the normally present lactobacilli. The condition isimplicated as a possible cause of preterm delivery. In our study, bacterial vaginosis was diagnosed clinically and microbiologically. The incidence of bacterial vaginosis in 72 pregnant women attending the Clinic for Pathologic Pregnancy (5,5%) was lower than that in 100 wo...

  13. Randomized controlled trial of probiotics for the prevention of spontaneous preterm delivery associated with intrauterine infection: study protocol

    Savastano Clarisse; Batista Maria; Camacho Karla G; Braga Alcione; Rezende Maria R; Alves Mariane B; Moreira Maria; Krauss-Silva Leticia; Almada-Horta Antonio; Guerra Fernando

    2010-01-01

    Abstract Background Spontaneous preterm deliveries that occur before the 34th week of gestation, and particularly before the 32nd week of gestation, have been strongly associated to intrauterine infection, ascending from vagina, and represent the largest portion of neonatal deaths and neurological problems. Bacterial vaginosis, characterized by a diminished or absent flora of lactobacilli and increased colonization of several anaerobic or facultative microorganisms, increases two times the ri...

  14. Dystopic dysplastic kidney with ectopic ureter: improved localization by fusion of MR urography and 99mTc-DMSA SPECT datasets

    We report a 12-year-old girl with a long history of constant urinary dribbling and apparently only a left kidney. Using a multimodality approach involving the fusion of MR urography and 99mTc-dimercaptosuccinic acid (DMSA) SPECT datasets, it was finally possible to exactly localize the very small dystopic, dysplastic right kidney and its ectopic ureter draining into the vagina. (orig.)

  15. Hybrid thoracic NOTES : a translational research project

    Pinto, João Moreira

    2014-01-01

    Tese de doutoramento em Medicina Natural Orifice Transluminal Endoscopic Surgery (NOTES) is considered the next step on minimally invasive surgery. NOTES uses endoscopes entering through any single or combination of natural orifices - mouth, urethra, vagina, and anus, in order to perform surgery inside the thorax or the abdomen. Its main purpose is providing scarless and less painful surgery to patients. To perform NOTES in the thorax, gastroenterologists and surgeons have focu...

  16. Isolation of quinupristin/dalfopristin-resistant Streptococcus agalactiae from asymptomatic Korean women.

    Nam, Hye Ran; Lee, Hak Mee; Lee, Yeonhee

    2008-02-01

    Seven Streptococcus agalactiae isolates were obtained from the vagina of 80 asymptomatic women. Three of these isolates showed multi-drug resistant (MDR) phenotypes: two isolates were resistant to clarithromycin, clindamycin, erythromycin, and tetracycline; and one isolate was resistant to clarithromycin, clindamycin, erythromycin, tetracycline, and quinupristin/dalfopristin. There was no clonal relationship among the MDR isolates. This is the first report of quinupristin/dalfopristin-resistant S. agalactiae. PMID:18337702

  17. Recurrent ectopic pregnancy in a woman suffering from infertility due to male factor presented with heterotopic pregnancy

    Chaudhari, Hemang D; Gandhi, Viplav S; Banker, Hiral; Suri, Amar

    2012-01-01

    Heterotopic pregnancy is the simultaneous occurrence of intrauterine and extrauterine pregnancies. A 27-year-old third gravida with history of two ectopic pregnancies, presented with cramping pain in pelvis radiating to left side and bleeding from vagina. Ultrasonographic diagnosis of heterotopic pregnancy was put forward. Unfortunately intrauterine component of heterotopic pregnancy resulted in blighted ovum and linear salpingostomy was done for left-sided tubal pregnancy.

  18. Angiomyofibroblastoma: A diagnostic dilemma

    Varuna Mallya

    2015-01-01

    Full Text Available Angiomyofibroblastoma is a very rare benign mesenchymal tumor of the superficial soft-tissues. Most of the cases have been reported in the vulva. It presents usually in the reproductive age group. Histologically it is characterized by alternating hypo and hypercellular areas admixed with thin walled blood vessels with a perivascular concentration of stromal cells. We report a case of this lesion arising in the vagina in a 46-year-old woman.

  19. Perineal template techniques for interstitial implantation of gynecological cancers using the Paris system of dosimetry

    Leung, S. (Peter MacCallum Cancer Institute, Melbourne Victoria (Australia))

    1990-09-01

    Since 1984, perineal template/needle techniques for interstitial implantation of gynecologic cancer-cervix, vagina, vulva-have been developed at the Peter MacCallum Cancer Institute. The Paris System of dosimetry has been used resulting in greater dose homogeneity, fewer needles and radioactive sources and considerable simplification and ease of implantation compared with comparable techniques developed in the United States. Principles and techniques of implantation are described in detail.

  20. Congenital Pouch Colon associated with Pseudoexstrophy: Report of Two Cases

    Praveen Jhanwar

    2016-01-01

    Full Text Available This report describes two newborn girls with single perineal opening (cloaca, and pseudoexstrophy in the form of divergent pubic bones and rectus muscles, and a low-set umbilicus. Both patients had a type II congenital pouch colon (CPC with one hemiuterus and vagina on each side in the pelvis. In one patient, a Meckel’s diverticulum was present 5 cm from the ileocecal junction. In both girls, a diverting proximal ileostomy was the initial surgery.

  1. Development and evaluation of acid-buffering bioadhesive vaginal tablet for mixed vaginal infections

    Alam, Mohd Aftab; Ahmad, Farhan Jalees; KHAN, ZEENAT IQBAL; Khar, Roop Krishen; ALI, MUSHIR

    2007-01-01

    An acid-buffering bioadhesive vaginal tablet was developed for the treatment of genitourinary tract infections. From the bioadhesion experiment and release studies it was found that polycarbophil and sodium carboxymethylcellulose is a good combination for an acid-buffering bioadhesive vaginal tablet. Sodium monocitrate was used as a buffering agent to provide acidic pH (4.4), which is an attribute of a healthy vagina. The effervescent mixture (citric acid and sodium bicarbonate) along with a ...

  2. Development of a multi-particulate formulation of viable bacteria for oral and vaginal delivery

    Poelvoorde, Nele

    2009-01-01

    The aim of this research project was to develop multi-particulate dosage forms for delivery of lactic acid bacteria: (a) the development of an oral dosage form containing a high concentration of viable, genetically modified, IL-10 producing Lactococcus lactis (b) the development of a formulation for delivery of health-promoting strains of lactic acid bacteria (referred to as probiotics) to the vagina. In addition to the viability of the lactobacilli strains incorporated in the formulation the...

  3. Structure, function and diversity of the healthy human microbiome.

    Curtis Huttenhower; Dirk Gevers; Rob Knight; Sahar Abubucker; Badger, Jonathan H.; Chinwalla, Asif T; Heather H. Creasy; Earl, Ashlee M.; FitzGerald, Michael G.; Fulton, Robert S.; Michelle G. Giglio; Kymberlie Hallsworth-Pepin; Lobos, Elizabeth A.; Ramana Madupu; Vincent Magrini

    2012-01-01

    Studies of the human microbiome have revealed that even healthy individuals differ remarkably in the microbes that occupy habitats such as the gut, skin, and vagina. Much of this diversity remains unexplained, although diet, environment, host genetics, and early microbial exposure have all been implicated. Accordingly, to characterize the ecology of human-associated microbial communities, the Human Microbiome Project has analyzed the largest cohort and set of distinct, clinically relevant bod...

  4. Anti-Adhesion Activity of A2-type Proanthocyanidins (a Cranberry Major Component) on Uropathogenic E. coli and P. mirabilis Strains

    Daria Nicolosi; Gianna Tempera; Carlo Genovese; Furneri, Pio M.

    2014-01-01

    Urinary tract infections (UTIs) are relatively common in women and may be classified as uncomplicated or complicated, depending upon the urinary tract anatomy and physiology. Acute uncomplicated cystitis (AUC) occurs when urinary pathogens from the bowel or vagina colonize the periurethral mucosa and reach the bladder. The vast majority of episodes in healthy women involving the same bacterial strain that caused the initial infection are thought to be reinfections. About 90% of AUC are caused...

  5. Comparative genomic and functional analysis of 100 Lactobacillus rhamnosus strains and their comparison with strain GG

    Douillard, F.P.; Ribbera, A.; Kant, R.; Pietilä, T.E.; Järvinen, H.M.; Messing, M.; Randazzo, C.L.; Paulin, L.; Laine, P.K.; Ritari, J.; Caggia, C.; Lähteinen, T.; Brouns, S.J.J.; Satokari, R.M.; Ossowski, von, I.

    2013-01-01

    Lactobacillus rhamnosus is a lactic acid bacterium that is found in a large variety of ecological habitats, including artisanal and industrial dairy products, the oral cavity, intestinal tract or vagina. To gain insights into the genetic complexity and ecological versatility of the species L. rhamnosus, we examined the genomes and phenotypes of 100 L. rhamnosus strains isolated from diverse sources. The genomes of 100 L. rhamnosus strains were mapped onto the L. rhamnosus GG reference genome....

  6. Comparative Genomic and Functional Analysis of 100 Lactobacillus rhamnosus Strains and Their Comparison with Strain GG

    Douillard, François P.; Ribbera, Angela; Kant, Ravi; Pietilä, Taija E.; Järvinen, Hanna M.; Messing, Marcel; Randazzo, Cinzia L.; Paulin, Lars; Laine, Pia; Ritari, Jarmo; Caggia, Cinzia; Lähteinen, Tanja; Brouns, Stan J. J.; Satokari, Reetta; von Ossowski, Ingemar

    2013-01-01

    Lactobacillus rhamnosus is a lactic acid bacterium that is found in a large variety of ecological habitats, including artisanal and industrial dairy products, the oral cavity, intestinal tract or vagina. To gain insights into the genetic complexity and ecological versatility of the species L. rhamnosus, we examined the genomes and phenotypes of 100 L. rhamnosus strains isolated from diverse sources. The genomes of 100 L. rhamnosus strains were mapped onto the L. rhamnosus GG reference genome....

  7. Pemeliharaan Kebersihan Diri Ibu Hamil di Kecamatan Medan Belawan

    Aramico, Sarwan

    2015-01-01

    Self-hygiene is an action to keep a person clean and healthy physically and psychologically. It includes hair care, leg and nail care, mouth hygiene, bathing, breast care, vulva/vagina care, and washing hands. The research used descriptive correlation method which was aimed to describe self-hygiene and some factors which influenced self-hygiene of pregnant women at Belawan 2 village, Medan Belawan Subdistrict. The samples were 50 respondents, taken by using convenience sampling technique. The...

  8. Candidiasis in Pediatrics; Identification and In vitro Antifungal Susceptibility of the Clinical Isolates

    MOHAMMADI, R.; Ataei, B

    2016-01-01

    Background Candida species are normal microflora of oral cavity, vagina, and gastrointestinal tract. They are the third most prevalent cause of pediatric health care–associated bloodstream fungal infection. This study aimed to provide an epidemiological feature of candidiasis and also presents an antifungal susceptibility profile of clinical Candida isolates among children. Materials and Methods During July 2013 to February 2015, 105 patients from different hospitals of Isfahan, Iran, were ex...

  9. An Overview of Neovaginal Reconstruction Options in Male to Female Transsexuals

    Marta Bizic; Vladimir Kojovic; Dragana Duisin; Dusan Stanojevic; Svetlana Vujovic; Aleksandar Milosevic; Gradimir Korac; Djordjevic, Miroslav L

    2014-01-01

    Transsexualism is a complex condition in which the person experiences the inconsistency between the desired gender and their biological gender. Absence of the vagina is devastating in male to female transsexuals. Creation of the neovagina is the main surgical problem in these patients. Historically, beginnings of the neovaginal creation have their roots in the treatment of Mayer-Rokitansky syndrome and conditions such as cloacal anomalies, certain intersex disorders, vaginal malignancies, or ...

  10. Apedunculata discoidea gen. n., sp. n. (Monogenea: Dactylogyridae) parasitic on Prochilodus lineatus (Valenciennes, 1837) (Characiformes: Prochilodontidae) from southeastern Brazil.

    Cuglianna, A M; Cordeiro, N S; Luque, J L

    2009-08-01

    A new species of dactylogyrid monogenean, Apedunculata discoidea gen. n., sp. n. is described and illustrated from the gills of the freshwater fish Prochilodus lineatus (Valenciennes, 1837) in pisciculture ponds from Pirassununga, São Paulo, Brazil. Diagnostic characters of the new genus and species are: 1) vagina dextrolateral slightly sclerotised, opening anteriorly at level of copulatory complex; 2) copulatory organ coiled with two counterclockwise rings; 3) Accessory piece distal and not articulated; 4) body disk-shaped, lacking a peduncle. PMID:19802450

  11. Streptococcus agalactiae vaginitis: nonhemolytic variant on the Liofilchem® Chromatic StreptoB

    Savini, Vincenzo; Marrollo, Roberta; D’Antonio, Marianna; D’Amario, Claudio; Fazii, Paolo; D’Antonio, Domenico

    2013-01-01

    Streptococcus agalactiae (group B Streptococcus, GBS) vaginal pathogenicity is not uniformly acknowledged throughout the literature; accordingly, in women, genital itching and burning, along with leukorrhea are commonly and almost exclusively referred to bacterial vaginosis, candidiasis and trichomoniasis. Conversely, GBS virulence for vagina was recognized in the past, as the organism has been observed to potentially cause local inflammation and discharge, as well as lactobacilli rarefaction...

  12. The vaginal colonization of group B streptococcus in females in the third trimester of their pregnancy

    ÖZEROL, Dr. İbrahim Halil; Baysal, Dr. Bülent; Şengil, Dr. A.Zeki

    1994-01-01

    Group B streptococcus, or Streptococcus agalactiae, was initially recognised as a cause of puerperal sepsis. Although the organism is still associated with this disease, it has more recently gained notoriety as a significant cause of septicemia, pneumonia, and meningitis in newborn children. Group B streptococci commonly colonize the upper respiratory tract, rectum and vagina. The colonization of group B Streptococcus was investigated in 100 females in the third trimester of their pregnancy b...

  13. 148 HPV, HIV, and Cancer: A Global Challenge

    Franceschi, Silvia

    2014-01-01

    The seminal discovery that human papillomavirus (HPV) infection causes cervical cancer provides an opportunity for prevention by vaccination and new screening approaches. Approximately 600,000 new cancer cases per year are attributable to HPV worldwide of which about half million in less developed countries (de Martel et al, Lancet Oncology, 2012). These cancers include all cervical cancers, the vast majority of anal cancers and approximately half of cancers of the vulva, vagina, and penis. I...

  14. 18F-Fluorodeoxyglucose PET/CT in a Patient with Esophageal and Genital Leiomyomatosis

    Diffuse esophageal leiomyomatosis is a rare benign tumor, which can be associated with leiomyoma in female genital tracts involving the uterus, vagina, and vulva. Alport syndrome, an inherited disorder that includes the kidneys, eyes, and sensorineural hearing loss, is also rarely associated with these multiple leiomyomatosis. In our case, 18F-fluoroseoxyglucose positron emission tomography/ computed tomography was used to distinguish esophageal and genital leiomyomatosis from malignant masses

  15. “My Work Constitutes a Form of Participatory Action”

    Yurong, Peng; Pernin, Judith

    2013-01-01

    Ai Xiaoming, born in 1953 in Wuhan, is a retired professor in the literature department of Guangzhou’s Sun Yat-Sen University. Following an academic career in comparative literature, she came out as a public intellectual, initially through involvement in defending women’s and gays rights. She organised many activities to raise awareness on issues such as discrimination and violence against women, the most famous of which was the translation and staging of The Vagina Monologueswith her student...

  16. Incomplete androgen insensitivity (Reifenstein syndrome) - a case report

    Turan, Volkan; Yeniel, Özgür; Ergenoğlu, Mete; Terek, Coşan; Ulukuş, Murat

    2010-01-01

    We report a 20 year old case of partial androgen insensitivity syndrome, referred to our clinic with complaints concerning external genital organs and left undescended testicle. The phenotypically male case was first evaluated for secondary sex development. Axillary hair was scanty and no pubic hair was found. There was no breast development. In the gynecological examination, the clitoris was hypertrophic (4.6 cm) and a blind vagina with intact hymen was seen. Abdominopelvic ultrasonography r...

  17. ANDROGEN INSENSITIVITY SYNDROME

    Kanan; Sonali

    2014-01-01

    The condition is inherited as X - linked recessive gene 1 . The underlying pathology is the inability of end organs to respond to androgens. These cases are phenotypically and psychologically female with adequate breast development , normal external genitalia , a vagina with variable depth , absent /sparse pubic hair and axillary hair. The exact incidence in India is not known but the reported incidence is 1 in 2 , 000 to 1 in 62 ,400 worldwi...

  18. Correlates of Occurrence of Obstetric Fistula among Women in Selected States of India: An Analysis of DLHS1-3 Data

    Gulati, B.K.; Unisa, S.; Pandey, A.; Sahu, D.; Ganguly, S.

    2011-01-01

    Obstetric fistula is the most devastating form of maternal morbidity. It is an opening in the wall of vagina connecting to bladder or to rectum due to prolonged obstructed labour without timely medical assistance. A few research studies carried out in India and recently conducted DLHS-3 survey (2007-08) has information on obstetric fistula that gives scope for further research. This paper examines prevalence of obstetric fistula and its correlates using DLHS-3 data for selected states in Indi...

  19. [Immediate vaginal reconstruction with a musculocutaneous flap from the gracilis muscle after extended abdomino-perineal resection].

    Sezeur, A; Hautefeuille, P; Trevidic, P

    1995-01-01

    Reconstruction of a functional vagina after radical abdomino-perineal resection is a difficult surgical problem. The use of the gracilis myocutaneous flap provides a satisfactory solution. This article describes the surgical procedure of immediate vaginal reconstruction using the gracilis myocutaneous flap. Unfortunately, this technique is still not widely used by surgical teams. Nevertheless, it is a useful flap because of its low morbidity and the satisfying result of the functional neovaginal cavity. PMID:8526447

  20. Tumors of the genitals in girls

    Literature data on the rate and character of neoplasms in girl's genitals are presented as well as morphological classification variants of ovary and germinogenetic neoplasms in particular and role of combined treatment different types. It is shown that in the case of ovary neoplasms the surgery, chemotherapy and (in certain cases) radiotherapy are used. As for rhabdomyosarcoma of vagina and neck of the uterus the treatment consists of chemotherapy and intracavitary radiotherapy

  1. Immune Cells in the Female Reproductive Tract

    Lee, Sung Ki; Kim, Chul Jung; Kim, Dong-Jae; Kang, Jee-Hyun

    2015-01-01

    The female reproductive tract has two main functions: protection against microbial challenge and maintenance of pregnancy to term. The upper reproductive tract comprises the fallopian tubes and the uterus, including the endocervix, and the lower tract consists of the ectocervix and the vagina. Immune cells residing in the reproductive tract play contradictory roles: they maintain immunity against vaginal pathogens in the lower tract and establish immune tolerance for sperm and an embryo/fetus...

  2. Reproductive performance of totally confined sheep bred with semen extended in a lactose-egg yolk-glycerol buffer and stored at 5 degrees C.

    Hackett, A J; Wolynetz, M. S.

    1982-01-01

    Two experiments were carried out in January and May 1975 to study reproductive performance (fertility, prolificacy and fecundity) of totally confined sheep synchronized for estrus. The main objective of the first experiment was to compare reproductive performance of ewes bred naturally to those bred by artificial insemination. Semen for artificial insemination was collected by either artificial vagina or electroejaculation and stored for up to 36 hours at 5 degrees C. A second objective was t...

  3. Hodnocení kvalitativních a kvantitativních ukazatelů spermií muflona obyčejného v průběhu roku

    Balážová, Bianka

    2014-01-01

    The object of this work was to evaluate kvantity and quality of sperm of mouflon (Ovis musimon) and theire fertilization ability, depending on month, season and presence of female. The samples were collected from 2 beings, age 2 and 4 years, from february 2013 to january 2014, in interval 1 time per month. The method of collection the ejaculate samples was electroejaculation by the full consciousness of animals in artificial vagina. The work is interesting in macroscopic and also microscopic ...

  4. Improved cryopreservation protocol for Blanca-Celtibérica buck semen collected by electroejaculation

    Jiménez Rabadán, Pilar; Ramón, Manuel; García Alvarez, Olga; Maroto Morales, Alejandro; Alvaro García, Pablo J.; Olmo, Enrique del; Pérez Guzmán, María Dolores; Fernández Santos, María del Rocío; Garde López-Brea, José Julián; Soler, Ana Josefa

    2013-01-01

    The collection of sperm samples by electroejaculation (EE) leads to an increase of the production of seminal plasma which could modify the tolerance of spermatozoa to the cryopreservation procedure. This study aims to compare a standard sperm cryopreservation protocol for samples collected by artificial vagina (AV) with the same protocol and modifications to this for samples obtained by EE. Semen from six males of Blanca-Celtibérica goat breed was collected by AV (control) and EE, and three e...

  5. Machine learning classifiers provide insight into the relationship between microbial communities and bacterial vaginosis

    BECK, Daniel; James A. Foster

    2015-01-01

    Background Bacterial vaginosis (BV) is a disease associated with the vagina microbiome. It is highly prevalent and is characterized by symptoms including odor, discharge and irritation. No single microbe has been found to cause BV. In this paper we use random forests and logistic regression classifiers to model the relationship between the microbial community and BV. We use subsets of the microbial community features in order to determine which features are important to the classification mod...

  6. [A neonate with ambiguous genitalia].

    Jansen, Burgo J; van Rijn, Rick R; van Trotsenburg, A S P Paul

    2015-01-01

    In a neonate with ambiguous genitalia, physical examination revealed a phallus. Ultrasonography showed a vagina and uterus, but no gonads. Because of severe undervirilisation in the presence of a uterus, probably due to 46,XY gonadal dysgenesis, parents were advised female sex assignment. When after a few weeks the phallus had increased in size, abdominal laparoscopy showed an underdeveloped uterus. Gonadal biopsy confirmed gonadal dysgenesis. Sex assignment was reconsidered and changed into the male gender. PMID:26200425

  7. Considerations of viscosity in the preliminaries to mammalian fertilisation

    Hunter, Ronald H. F.; Coy, P; Gadea, J.; Rath, D

    2011-01-01

    Migration of spermatozoa in the female genital tract will be strongly influenced by the viscosity of the fluids encountered, yet little systematic analysis has been given to such a consideration. This essay reviews the series of milieux confronting a fertilising sperm during its progression to the oviduct ampulla. Two groups are discussed, first those in which ejaculation is into the vagina, second those in which semen enters the uterus during a protracted mating. Viscous glycoprotein secreti...

  8. Development of HIV-1 Rectal-Specific Microbicides and Colonic Tissue Evaluation

    Dezzutti, Charlene S.; Russo, Julie; Wang, Lin; Abebe, Kaleab Z.; Li, Jie; David R. Friend; McGowan, Ian M.; Rohan, Lisa C.

    2014-01-01

    The gastrointestinal tract is structurally and functionally different from the vagina. Thus, the paradigm of topical microbicide development and evaluation has evolved to include rectal microbicides (RMs). Our interest was to create unique RM formulations to safely and effectively deliver antiretroviral drugs to mucosal tissue. RMs were designed to include those that spread and coat all surfaces of the rectum and distal colon rapidly (liquid) and those that create a deformable, erodible barri...

  9. Insects are Crawling in My Genital Warts

    Jyoti Dhawan; Saurabh Singh; Somesh Gupta

    2011-01-01

    A 23-year-old woman presented with large exophytic genital wart arising from perineum, vulva, introitus of the vagina, and inner aspect of thighs. Patient developed severe itching and formication (insect-crawling sensation) in the lesions for past 1 week, though careful examination did not reveal any insects. Considering that the disease was causing psychological stress and physical symptoms, radiofrequency excision was planned. However, during the procedure, several maggots appeared from the...

  10. Does cancer start in the womb? Altered mammary gland development and predisposition to breast cancer due to in utero exposure to endocrine disruptors

    SOTO, ANA M.; Brisken, Cathrin; Schaeberle, Cheryl; Sonnenschein, Carlos

    2013-01-01

    We are now witnessing a resurgence of theories of development and carcinogenesis in which the environment is again being accepted as a major player in phenotype determination. Perturbations in the fetal environment predispose an individual to disease that only becomes apparent in adulthood. For example, gestational exposure to diethylstilbestrol resulted in clear cell carcinoma of the vagina and breast cancer. In this review the effects of the endocrine disruptor bisphenol-A (BPA) on mammary ...

  11. Pengetahuan Ibu Pasca Salin Terhadap Perawatan Luka Perineum Di Klinik Fajar Tahun 2015

    Satrima, Lely

    2016-01-01

    Background: birth canal injury is a strong predisposition to infection during childbirth. Approximately 22.5% of maternal deaths in Indonesia are caused by infection after the copy, this happens because of the wound lacerations in the genital tract, including episiotomy on the perineum, the walls of the vagina and cervix. Injury to the perineum due to uterine rupture or laceration episiotomy is an area that is not easily dry. To prevent infection need to be considered, especially on the first...

  12. Aggressive angiomyxoma of the vulva presenting as a pedunculated swelling

    Mandal Shramana

    2008-04-01

    Full Text Available Aggressive angiomyxoma is a rare, locally aggressive soft tissue tumor that has high propensity for local recurrence. It involves mainly the pelvis, vulva, perineum, vagina and urinary bladder in adult women in the reproductive age. Considering its locally aggressive nature, appropriate management and long-term follow-up is necessary. We describe a case of a 22-year-old young pregnant patient presenting with a large pedunculated swelling on the left labia majora.

  13. Tindakan Episiotomi pada Persalinan Primipara yang Bersalin di Bidan di Kelurahan Bela Rakyat Kecamatan Kuala Kabupaten Langkat Tahun 2013

    Tanjung, Lyria Novita

    2015-01-01

    Latar belakang : Episiotomi adalah suatu tindakan insisi pada perineum yang menyebabkan terpotongnya selaput lendir vagina, cincin selaput dara, jaringan pada septum rektovaginal, otot-otot dan fasia perineum dan kulit sebelah depan perineum. Tujuan penelitian : Penelitian ini bertujuan untuk mengetahui jumlah tindakan episiotomi pada persalinan primipara yang bersalin di bidan praktek di Kelurahan Bela Rakyat Kecamatan Kuala Kabupaten Langkat Tahun 2013. Metodologi : Penelitian ini men...

  14. Fibromatosis in vertical rectus abdominis myocutaneous flap imitating tumor recurrence after surgery for locally advanced rectal cancer: case report

    Goscinski, Mariusz Adam; Hole, Knut Håkon; Tønne, Elin; Ryder, Truls; Grøholt, Krystyna Kotanska; Flatmark, Kjersti

    2016-01-01

    Background Abdominoperineal excision is performed in patients with locally advanced, low rectal carcinoma. Reconstruction of the dorsal vagina and perineum using the vertical rectus abdominis myocutaneous flap following extensive surgery results in favorable surgical outcome and quality of life. However, the rectus abdominis muscle, as part of the anterior abdominal wall, may develop fibrous lesions also as a transplant. Case presentation A 39-year-old female patient with low rectal cancer an...

  15. CONGENITAL VESICOUTERINE FISTULA ALONG WITH DISTAL VAGINAL AGENESIS, SOLITARY KIDNEY AND TONGUE TIE: A RARITY

    Khalid; Amit; Rana Pratap; Ahsan; Takallum

    2015-01-01

    : Congenital vesicouterine fistula in association with vaginal agenesis and solitary renal agenesis has been rarely reported. We present a case of 19 year old female suffering from cyclical menouria for last years. Physical examination revealed absence of vagina. IVP revealed left renal agenesis and CT scan revealed left renal agenesis with vesicouterine fistula. Cystoscopy showed vesicouterine fistula located above trigone near midline. Vesicouterine fistula was repaired along wi...

  16. Longitudinal analysis of the vaginal microflora in pregnancy suggests that L. crispatus promotes the stability of the normal vaginal microflora and that L. gasseri and/or L. iners are more conducive to the occurrence of abnormal vaginal microflora

    Temmerman Marleen; De Backer Ellen; Claeys Geert; Verhelst Rita; Verstraelen Hans; Vaneechoutte Mario

    2009-01-01

    Abstract Background Despite their antimicrobial potential, vaginal lactobacilli often fail to retain dominance, resulting in overgrowth of the vagina by other bacteria, as observed with bacterial vaginosis. It remains elusive however to what extent interindividual differences in vaginal Lactobacillus community composition determine the stability of this microflora. In a prospective cohort of pregnant women we studied the stability of the normal vaginal microflora (assessed on Gram stain) as a...

  17. Effect of vaginal distention on elastic fiber synthesis and matrix degradation in the vaginal wall: potential role in the pathogenesis of pelvic organ prolapse

    Rahn, D. D.; Acevedo, J. F.; Word, R A

    2008-01-01

    Matrix metalloprotease (MMP) activity is increased in the postpartum vagina of wild-type (WT) animals. This degradative activity is also accompanied by a burst in elastic fiber synthesis and assembly. The mechanisms that precipitate these changes are unclear. The goals of this study were to determine how vaginal distention (such as in parturition) affects elastic fiber homeostasis in the vaginal wall and the potential significance of these changes in the pathogenesis of pelvic organ prolapse....

  18. What is the Health Risk Associated with Amenorrhea?

    Vrkljan, Milan; Brkić, Marijo; Zečević, Ana-Marija; Topić, Patricija

    2001-01-01

    Amenorrhea is one of the most common symptoms in the woman’s health pathology. It can be caused by anatomical defects of the outflow tract (uterus, cervix, vagina), thus being in the gynecologist’s domain, or can be observed in gonadal dysgenesis (Turner’s syndrome), hypopituitarism (Sheehan’s syndrome), prolactin-secreting pituitary tumors, Cushing’s syndrome, hyperthyroidism, stress, anorexia nervosa, polycystic ovaries, and in women upon discontinuation of oral contraceptives, especially i...

  19. Complex Genital Malformation in a Female with Congenital Adrenal Hyperplasia: Evaluation with Magnetic Resonance Imaging

    This is a case of complex genital malformation in a young patient with congenital adrenal hyperplasia. The magnetic resonance imaging (MRI) findings included ostium of the vagina into the urethra (common urogenital opening), prostate-like tissue surrounding the urethra, and hyperplasia of the left adrenal gland. The report provides information on the clinical findings, the MRI examination, including the applied sequences and the MR findings, and gives an overview of the disease pattern and its frequency of occurrence

  20. Cytoprotective Effect of Lactobacillus crispatus CTV-05 against Uropathogenic E. coli

    Daniel S. C. Butler; Aurelio Silvestroni; Ann E. Stapleton

    2016-01-01

    The vaginal flora consists of a subset of different lactic acid producing bacteria, typically creating a hostile environment for infecting pathogens. However, the flora can easily be disrupted, creating a favorable milieu for uropathogenic Escherichia coli (UPEC), making it possible to further infect the urinary system via the urethra. Probiotic use of different lactobacilli to restore the normal flora of the vagina has been proposed as a potential prophylactic treatment against urinary tract...

  1. Recovery of Mycoplasma spp. from the Reproductive Tract of the Mare during the Estrous Cycle

    Bermudez, Victor; Miller, Richard; Johnson, Walter; Rosendal, Soren; Ruhnke, Louise

    1987-01-01

    The sites in the genital tract from which mycoplasmas could be recovered at various stages of the estrous cycle were studied in five Standardbred mares naturally infected with Mycoplasma. Mycoplasma equigenitalium and Mycoplasma subdolum were most frequently isolated from the clitoral fossa as compared to the vagina, cervix, and uterus. The lowest isolation prevalence was observed in the uterus. The recovery of Mycoplasma spp. from the clitoral fossa did not differ at any stage of the estrous...

  2. The robotic metroplasty in a patient with hybrid septate variant anomaly.

    Güngör, Mete; Afşar, Selim; Özbaşlı, Esra; Genim, Canan Erdem

    2016-09-01

    Complete uterovaginal septum is unusually associated with an obstructed left hemivagina and hemiuteri. Herein we present a case report of "hybrid septate variant" anomaly diagnosed in a 16-year-old girl. The uterine septum could not be completely removed hysteroscopically because of the obstructed vagina and thick uterine septum; therefore an abdominal approach, robotic metroplastic surgery was performed. We propose that the robotic technology has advantages over the classical laparoscopy related with the surgical correction of Müllerian anomaly. PMID:26873541

  3. Vaginal Atrophy following Long-Term Depot Medroxyprogesterone Acetate Use: A Case Report

    Christie Walker; Badawy, Shawky Z. A.

    2013-01-01

    Depot medroxyprogesterone acetate (DMPA) is a commonly used form of contraception, with noncontraceptive benefits for the user. The mode of action is through the suppression of ovulation. It leads to hypoestrogenism which causes dryness of the vagina and dyspareunia. We present in this paper a patient that was very symptomatic with regard to vaginal atrophic changes determined by vaginal cytology. This side effect may become increasingly more common as we see more long-term use of DMPA.

  4. Vaginal Atrophy following Long-Term Depot Medroxyprogesterone Acetate Use: A Case Report

    Christie Walker

    2013-01-01

    Full Text Available Depot medroxyprogesterone acetate (DMPA is a commonly used form of contraception, with noncontraceptive benefits for the user. The mode of action is through the suppression of ovulation. It leads to hypoestrogenism which causes dryness of the vagina and dyspareunia. We present in this paper a patient that was very symptomatic with regard to vaginal atrophic changes determined by vaginal cytology. This side effect may become increasingly more common as we see more long-term use of DMPA.

  5. TRANSVAGINAL VERSUS TRANSGASTRIC ENDOSCOPIC PERITONEAL APPROACH – A COMPARATIVE EXPERIMENTAL STUDY

    S. Patrascu; V. Surlin; E. Georgescu; A. Olaru; Georgescu, I.

    2011-01-01

    Background: During the last 30 years the advent of laparoscopy and interventional endoscopy induced the emergence of a new approach - Natural Orifice Translumenal Endoscopic Surgery (N.O.T.E.S.) in which the peritoneal cavity is accessed through stomach, vagina or other natural orifice, as a even lesser minimally invasive surgery. Method: A total of 8 female pigs (20-35 kg), were assigned to either transgastric or transvaginal endoscopic procedures. General anesthesia with orotracheal intuba...

  6. Prevention of cervical, vaginal, and vulval cancers: role of the quadrivalent human papillomavirus (6, 11, 16, 18) recombinant vaccine

    Maria Lina Diaz

    2010-01-01

    Maria Lina DiazSection of Ambulatory Gynecology Cleveland Clinic Florida Weston, Florida, USAAbstract: The relationship between the human papillomavirus (HPV) and malignancies of the uterine cervix, vagina, and vulva has been established. The development of a quadrivalent HPV recombinant prophylactic vaccine represents the first time in history that primary prevention of these cancers is offered to girls and women. The prevalence of oncogenic HPV subtypes in cervical cancers has been the most...

  7. Vaginosis bacteriana por Gardnerella vaginalis: Nuevas enseñanzas desde la ecología molecular

    Andrés Zúñiga; Fabián Tobar-Tosse

    2015-01-01

    La vaginosis bacteriana (VB), es la afección vaginal más frecuente en las mujeres en edad reproductiva generada por un desbalance en el ecosistema vaginal que ocasiona complicaciones severas para la salud reproductiva. Existen hipótesis de origen biológico que relacionan la presencia de organismos como Gardnerella vaginalis, Prevotella sp, Atopobium vaginae como la causa más frecuente relacionada con la vaginosis, los cuales logran desplazar poblacionalmente microorganismos con capacidad prot...

  8. Streptococcus equi subsp. zooepidemicus isolates from equine infectious endometritis belong to a distinct genetic group

    Rasmussen, Camilla Dooleweerdt; Haugaard, Maria Mathilde; Petersen, Morten Roenn; Nielsen, Jesper Møller; Pedersen, Hanne Gervi; Bojesen, Anders Miki

    2013-01-01

    Streptococcus equi subsp. zooepidemicus is the pathogen most commonly isolated from the uterus of mares. S. zooepidemicus is an opportunistic pathogen and part of the resident flora in the caudal reproductive tract. The aim of this study was to investigate whether a genotypically distinct subpopulation of S. zooepidemicus is associated with endometritis in the mare, by genotyping and comparing uterine S. zooepidemicus strains with isolates from the vagina and clitoral fossa. Mares with (n = 1...

  9. Comparative study of some local therapeutics for endometritis in cows

    E. B. Basheer; M. B. Taha

    2008-01-01

    The present study was conducted on 57 local breed cows suffering from various degrees of endometritis. The clinical examination included visual examination of vagina supported by uterine palpation per rectum; the laboratory examination included the bacterial isolation from the uterine swabs and histopathological examination of the uterine biopsies. Animals were randomly divided in to three groups of 15 cows each and 12 cows were considered as a control group received no treatment and observed...

  10. Acute pyelonephritis and secondary bacteraemia caused by Veillonella during pregnancy

    Yagihashi, Yusuke; Arakaki, Yoshitaka

    2012-01-01

    We report a case of pyelonephritis and secondary bacteraemia caused by Veillonella species during pregnancy. Veillonella is part of the normal flora from the oral cavity, gut and vagina. However, because Veillonella is usually isolated from cultures of clinical specimens as part of commensal flora, it is frequently regarded as a contaminant. In the present case, Veillonella was isolated from the patient's urine and blood samples that showed evidence of pyelonephritis and secondary bacteraemia...

  11. Characterization of biofilm-forming microorganisms isolated from vaginal exudate in Portugal

    Alves, P.; Castro, J.; Cereija, Tatiana Barros Reis; Henriques, Ana Filipa Frutuoso Mendes; Cerca, Nuno

    2012-01-01

    Bacterial vaginosis (BV) is one of the most common gynaecological conditions affecting women in the reproductive age, and can lead to increase risk gynaecological infections and pre-term labour. The aetiology of this pathology is still poorly understood, but recent reports referring to the presence of anaerobic biofilms both in the healthy and BV vagina (with different microbial compositions) have led to the theory that the microorganisms that form biofilms may be relevant for the aetiology o...

  12. Bacterial Vaginosis Biofilms: Challenges to Current Therapies and Emerging Solutions

    Machado, Daniela; Castro, Joana; Palmeira-de-Oliveira, Ana; Martinez-de-Oliveira, José; Cerca, Nuno

    2016-01-01

    Bacterial vaginosis (BV) is the most common genital tract infection in women during their reproductive years and it has been associated with serious health complications, such as preterm delivery and acquisition or transmission of several sexually transmitted agents. BV is characterized by a reduction of beneficial lactobacilli and a significant increase in number of anaerobic bacteria, including Gardnerella vaginalis, Atopobium vaginae, Mobiluncus spp., Bacteroides spp. and Prevotella spp.. ...

  13. Anaerobes and Bacterial Vaginosis in Pregnancy: Virulence Factors Contributing to Vaginal Colonisation

    Africa, Charlene W.J.; Janske Nel; Megan Stemmet

    2014-01-01

    The aetiology and pathogenesis of bacterial vaginosis (BV) is unclear but it appears to be associated with factors that disrupt the normal acidity of the vagina thus altering the equilibrium between the normal vaginal microbiota. BV has serious implications for female morbidity, including reports of pelvic inflammatory disease, adverse pregnancy outcomes, increased susceptibility to sexually transmitted infections and infertility. This paper reviewed new available information regarding poss...

  14. The influence of biofilm formation by Gardnerella vaginalis and other anaerobes on bacterial vaginosis

    Machado, António; Cerca, Nuno

    2015-01-01

    Bacterial vaginosis (BV) is the worldwide leading vaginal disorder in women of reproductive age. BV is characterized by the replacement of beneficial lactobacilli and the augmentation of anaerobic bacteria. Gardnerella vaginalis is a predominant bacterial species, however, BV is also associated with other numerous anaerobes, such as Atopobium vaginae, Mobiluncus mulieris, Prevotella bivia, Fusobacterium nucleatum and Peptoniphilus sp.. Currently, the role of G. vaginalis in the etiology of BV...

  15. Interstitial radiotherapy for early stage vaginal cancer. A new method of tumor localization.

    Finan, M A; Hoffman, M S; Greenberg, H; Roberts, W S; Cavanagh, D; Fiorica, J V

    1993-03-01

    Carcinoma of the vagina is optimally treated primarily with teletherapy, followed by interstitial needle brachytherapy. Following teletherapy, identification of the original tumor site is frequently difficult. We describe a method of marking the tumor with an india ink "tattoo" at initial presentation, followed by placement of a purse-string suture and titanium hemoclips at the time of brachytherapy. A stable marker is created so that the location of the original vaginal tumor can be easily identified on dosimetric films. PMID:7683723

  16. Other Gynecologic Cancers: endometrial, ovarian, vulvar and vaginal cancers

    Duarte-Franco, Eliane; Franco, Eduardo L.

    2004-01-01

    Health issue In Canada, cancers of the endometrium, ovaries, vulva, vagina, placenta and adnexa account for 11% of all malignant neoplasms in women and 81% of all genital cancers. Although the incidence and mortality from vulvar and vaginal cancers are very low, endometrium and ovarian cancer are important public health problems. Key findings In Canada, there has been no appreciable improvement in survival for women with advanced endometrial (EC) or ovarian cancer (OC) over the past 30 years....

  17. DISORDER OF SEX DEVELOPMENT: DESCRIPTION OF 2 CASES OF MALE PSEUDOHERMAPHRODITISM

    C. Varetti

    2012-01-01

    Full Text Available Introduction. "Genetic errors" with malformations and hormonal alterations result in a broad spectrum of disorders of sexual identity difficult to classify for etiopathogenesis and anatomy. Male pseudohermaphroditism (PEM is the result of defects in masculinisation, persistence of mullerian ducts or genital malformations. In these patients, there is always a 46 XY karyotype, male gonads with the external genitalia and phenotype completely or partially female. The authors describe 2 cases of PEM. Patients and Methods. RS and HNA, 9 and 15 years old. Both had 46 XY karyotype and female phenotype with the presence of penile clitoris and small vagina. The urethral meatus was positioned at the base of the penile clitoris and upper vagina and testicles, were located at the proximal portion of the inguinal canal.Patients were subjected to MRI showing absence of uterus and ovaries. The endoscopy described a small vagina dead-end about 4-5 cm long. Complete resection of the vagina, bilateral orchiopexy, correction of perineal hypospadias with urethral tubulization, reconstruction of the scrotum, with the results of penoscrotal hypospadias were performed. Discussion. Sexual differentiation is the process between VII and XII weeks of gestational age leading to formation of male or female fetus from embryo potentially bisexual. Brain Code gender is bipolar: male or female. In the sexual disorders there is a discrepancy between anatomical sex and the brain code. Genital malformation with a direct mechanism (external genitalia and indirect (prenatal pathological imprinting on all the receptors of target organs may exacerbate the brain deterioration of the code resulting in disease patterns difficult to manage according psychological and surgical aspects. Conclusions. Pediatric Surgeon plays a key role in the treatment of genital anomalies. Valutation of pelvic-perineal anatomy is important for the choice of sexual phenotype and related surgical strategy

  18. THE ANALYSIS OF STATISTICAL DATA ON MALIGNANT NEOPLASMS ASSOCIATED WITH HUMAN P APILLOMAVIRUS

    A. A. Kostin

    2016-01-01

    Full Text Available In this study of statistical data for the first time in Russia the analysis of the morbidity and mortality of patients with malignant neoplasms that may be associated with human papilloma virus (HPV is performed: cervical cancer (cervical cancer, cancer of the vulva and vagina, cancer of penis, cancer of the rectum, anal canal and rectosigmoid junction cancer, cancer of the pharynx and larynx.

  19. Nephrogenic adenoma arising from the urinary bladder: a case report

    Chung, Sun Hee; Lee, Sun Wha; Han, Woon Seup [Ewha Womans Univ. College of Medicine, Seoul (Korea, Republic of)

    2001-03-01

    Nephrogenic adenoma is a benign metaplastic lesion of the urinary tract occurring most frequently at the urinary bladder. It is very rare, especially in children. We describe the US, CT and MRI findings of nephrogenic adenoma arising from the urinary bladder in an 8-year-old girl who suffered rupture of the bladder, urethra and vagina after a traffic accident and whose condition was complicated by urethral stricture and vesicoureteral reflux.

  20. [Case Reports] Successful pregnancy foilowing gamete intrafallopian transfer in a patient with a transverse vaginal septum: case report

    Ami, Kazumi; TSUJI, ISAO; Watanabe, Yo; Fujinami, Nahoko; MIYAZAKI, Ayako; Hoshiai, Hiroshi

    2010-01-01

    [Abstract] Transverse vaginal septa (TVSs) are rare congenital, obstructive vaginal anomalies resulting from a defect of vertical fusion during embryogenesis of the vagina and are generally diagnosed at the time of pregnancy in association with obstetric complications. TVSs also contribute to infertility. Surgical treatment, such as resection or fenestration of the TVS, is generally indicated. However, the optimal treatment of infertile patients with TVS has not been established, and few case...