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Sample records for Vagina

  1. Malignant melanoma of the vagina.

    OpenAIRE

    Rahat ARA; Saw OHNMAR

    2011-01-01

    Carcinoma of the vagina is uncommon and only constitutes two percent of malignant neoplasms of the female genital tract. Malignant melanoma of the vagina is rarer and accounts for only 3.2% of all vaginal cancers. It presumably arises from melanocytes found in the vagina of three percent of normal women. It is a very aggressive tumour and the overall prognosis is poor despite the treatment. We report the case of an 81-year-old woman who presented with per vagina bleeding secondary to a malign...

  2. Antibiotic susceptibility of Atopobium vaginae

    Directory of Open Access Journals (Sweden)

    Verschraegen Gerda

    2006-03-01

    Full Text Available Abstract Background Previous studies have indicated that a recently described anaerobic bacterium, Atopobium vaginae is associated with bacterial vaginosis (BV. Thus far the four isolates of this fastidious micro-organism were found to be highly resistant to metronidazole and susceptible for clindamycin, two antibiotics preferred for the treatment of BV. Methods Nine strains of Atopobium vaginae, four strains of Gardnerella vaginalis, two strains of Lactobacillus iners and one strain each of Bifidobacterium breve, B. longum, L. crispatus, L. gasseri and L. jensenii were tested against 15 antimicrobial agents using the Etest. Results All nine strains of A. vaginae were highly resistant to nalidixic acid and colistin while being inhibited by low concentrations of clindamycin (range: G. vaginalis strains were also susceptible for clindamycin ( 256 ?g/ml but susceptible to clindamycin (0.023 – 0.125 ?g/ml. Conclusion Clindamycin has higher activity against G. vaginalis and A. vaginae than metronidazole, but not all A. vaginae isolates are metronidazole resistant, as seemed to be a straightforward conclusion from previous studies on a more limited number of strains.

  3. Embryonal rhabdomyosarcoma of the vagina in children

    International Nuclear Information System (INIS)

    Eight cases of childhood rhabdomyosarcoma arising in the vagina are presented. All were treated with curie therapy, and 7 of 8 received chemotherapy in addition. With a median follow up of 4 yr, 6 of 7 had local control without surgery, 1 required colpohysterectomy for microscopic disease after curie therapy. These techniques of curie therapy and chemotherapy for localized rhabdomyosarcoma of the vagina allow one to obtain the cure while avoiding mutilating surgery. (author)

  4. Adenocarcinoma de células claras de la vagina

    Scientific Electronic Library Online (English)

    Rubén, Urrejola S.; Ana María, Carrasco T.; Fernando, Heredia M..

    Full Text Available Se presenta un caso clínico de adenocarcinoma de células claras de vagina en mujer de 23 años, sin antecedentes de exposición intrauterina a dietilestilbestrol. Se efectuó colpohisterectomía radical, linfadenectomía pélvica completa y ooforopexia bilateral, más radioterapia externa adyuvante (45 Gy) [...] . Sin evidencia de enfermedad a 5 meses de completada su terapia Abstract in english A case of clear cell adenocarcinoma of the vagina in a 23 year old woman, without diethylstilbestrol intrauterine exposure, is presented. The surgical and the radiotherapy treatment are discussed. Without evidence of disease at 5 months follow up. A brief discussion of literature is also provided [...

  5. Adenocarcinoma de células claras de la vagina

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    Rubén Urrejola S.

    2004-01-01

    Full Text Available Se presenta un caso clínico de adenocarcinoma de células claras de vagina en mujer de 23 años, sin antecedentes de exposición intrauterina a dietilestilbestrol. Se efectuó colpohisterectomía radical, linfadenectomía pélvica completa y ooforopexia bilateral, más radioterapia externa adyuvante (45 Gy. Sin evidencia de enfermedad a 5 meses de completada su terapiaA case of clear cell adenocarcinoma of the vagina in a 23 year old woman, without diethylstilbestrol intrauterine exposure, is presented. The surgical and the radiotherapy treatment are discussed. Without evidence of disease at 5 months follow up. A brief discussion of literature is also provided

  6. Imaging of the vagina and vulva

    International Nuclear Information System (INIS)

    In gynecological daily practices, the vulva and vagina are examined during physical examination, however there are situations where this is not possible or it is needed to determine the extension of an injury through imaging methods. The magnetic resonance imaging is an excellent cross-sectional modality for evaluation the alterations of vulva and vagina due its multiplanar evaluation and high tecidual contrast. Other cross-sectional modalities are ultrasound and enhanced computed tomography. This paper intends to give an overview of vaginal and vulvar pathology that can be identified by the radiologist. (author)

  7. Cáncer primario de vagina Vaginal primary cancer

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    Raiza Ruiz Lorente

    2010-09-01

    Full Text Available El carcinoma primario de vagina es una neoplasia poco frecuente, representando solamente el 1-2 % de todos los tumores malignos del área ginecológica. Según la FIGO solo se considera como cáncer primario de vagina a aquellas lesiones confinadas a la vagina sin invasión del cuello uterino o la vulva. El pronóstico depende principalmente del estadio en que se encuentra la enfermedad, pero la supervivencia se reduce en pacientes mayores de 60 años de edad, si son sintomáticos al momento del diagnóstico, tienen lesiones del centro y tercio inferior de la vagina o tienen tumores mal diferenciados. Los objetivos de este estudio fueron evaluar la experiencia en el manejo del cáncer primario de vagina, identificar variables demográficas y clínicas, mostrar la variedad histológica de presentación de esta neoplasia tan rara, así como el grado de diferenciación en cada caso. Igualmente relacionar estadio del cáncer, tratamiento y respuesta en cada una de las pacientes. Se trata de un estudio retrospectivo de cinco pacientes con cáncer primario de vagina atendidas en el Servicio de Patología de cuello del Hospital Ramón González Coro, durante el año 2008. La evaluación inicial consistió en una historia clínica completa, examen físico haciendo hincapié en el área ginecológica descartando lesiones en vulva o cuello uterino. A todas las pacientes se les realizó biopsia excisional del tumor, enviando la muestra al estudio histopatológico. Se les realizó cistoscopia, rectoscopia, urograma descendente, a aquellas pacientes con sospecha de infiltración de vejiga o recto, laboratorio, radiografía del tórax y se estadiaron según la clasificación de la FIGO.The primary vaginal carcinoma is a uncommon neoplasm present only in the 1-2% of all the malignant tumors of gynecology area. According to International Federation of Gynecology and Obstetrics only is considered as a primary vaginal cancer of those lesions confined to vagina without invasion of cervix or the vulva. The prognosis depends mainly on the disease stage, but the survival is reduced in patients aged over 60 if they are symptomatic at diagnosis, have lesions of the center and the inferior third of vagina or have ill-differentiated. The objectives of present study were to assess the experience in the vaginal primary cancer management, to identify demographic and clinical variables, to show the histological variety of presentation of this so rare neoplasm, as well as the differentiation grade of each case and to relate the cancer stage, the treatment and the response of each patient. It is retrospective study conducted in 5 patients presenting vaginal primary cancer seen in the Cervix Pathology Service of the "Ramón González Coro" Gynecology and Obstetrics Hospital during 2008. The initial assessment included a complete medical record, physical examination with emphasis in the gynecological area ruling out vulva or cervix uteri lesions. All patients underwent excision biopsy of tumor with the corresponding histopathological study of the sample. A cystoscopy, rectoscopy descending urogram were carried out in those patients with a possible bladder or rectum infiltration, lab tests, thorax Rx staged according the International Federation of Gynecology and Obstetrics classification.

  8. Cáncer primario de vagina / Vaginal primary cancer

    Scientific Electronic Library Online (English)

    Raiza, Ruiz Lorente; Daisy, Hernández Durán; Tania Graciela, Tamayo Lien; Ana Isabel, de la Torre.

    2010-09-01

    Full Text Available El carcinoma primario de vagina es una neoplasia poco frecuente, representando solamente el 1-2 % de todos los tumores malignos del área ginecológica. Según la FIGO solo se considera como cáncer primario de vagina a aquellas lesiones confinadas a la vagina sin invasión del cuello uterino o la vulva. [...] El pronóstico depende principalmente del estadio en que se encuentra la enfermedad, pero la supervivencia se reduce en pacientes mayores de 60 años de edad, si son sintomáticos al momento del diagnóstico, tienen lesiones del centro y tercio inferior de la vagina o tienen tumores mal diferenciados. Los objetivos de este estudio fueron evaluar la experiencia en el manejo del cáncer primario de vagina, identificar variables demográficas y clínicas, mostrar la variedad histológica de presentación de esta neoplasia tan rara, así como el grado de diferenciación en cada caso. Igualmente relacionar estadio del cáncer, tratamiento y respuesta en cada una de las pacientes. Se trata de un estudio retrospectivo de cinco pacientes con cáncer primario de vagina atendidas en el Servicio de Patología de cuello del Hospital Ramón González Coro, durante el año 2008. La evaluación inicial consistió en una historia clínica completa, examen físico haciendo hincapié en el área ginecológica descartando lesiones en vulva o cuello uterino. A todas las pacientes se les realizó biopsia excisional del tumor, enviando la muestra al estudio histopatológico. Se les realizó cistoscopia, rectoscopia, urograma descendente, a aquellas pacientes con sospecha de infiltración de vejiga o recto, laboratorio, radiografía del tórax y se estadiaron según la clasificación de la FIGO. Abstract in english The primary vaginal carcinoma is a uncommon neoplasm present only in the 1-2% of all the malignant tumors of gynecology area. According to International Federation of Gynecology and Obstetrics only is considered as a primary vaginal cancer of those lesions confined to vagina without invasion of cerv [...] ix or the vulva. The prognosis depends mainly on the disease stage, but the survival is reduced in patients aged over 60 if they are symptomatic at diagnosis, have lesions of the center and the inferior third of vagina or have ill-differentiated. The objectives of present study were to assess the experience in the vaginal primary cancer management, to identify demographic and clinical variables, to show the histological variety of presentation of this so rare neoplasm, as well as the differentiation grade of each case and to relate the cancer stage, the treatment and the response of each patient. It is retrospective study conducted in 5 patients presenting vaginal primary cancer seen in the Cervix Pathology Service of the "Ramón González Coro" Gynecology and Obstetrics Hospital during 2008. The initial assessment included a complete medical record, physical examination with emphasis in the gynecological area ruling out vulva or cervix uteri lesions. All patients underwent excision biopsy of tumor with the corresponding histopathological study of the sample. A cystoscopy, rectoscopy descending urogram were carried out in those patients with a possible bladder or rectum infiltration, lab tests, thorax Rx staged according the International Federation of Gynecology and Obstetrics classification.

  9. Linfoma no Hodgkin primario de vagina

    Scientific Electronic Library Online (English)

    Eva María, Guldrís N; María Pía, Vázquez C; Elba, Carballo N; Magdalena, Porto Q; Luis, Heliodoro Alba O; Begoña, Iglesias R.

    Full Text Available La afectación primaria del tracto genital femenino de los linfomas no Hodgkin es poco frecuente (2% de los linfomas primarios extraganglionares). Los órganos más afectados son los ovarios seguidos del cérvix, siendo la localización endometrial y vaginal extremadamente rara. Presentamos el caso de un [...] a paciente de 44 años diagnosticada de linfoma primario de vagina, estadio IE A, con remisión completa tras tratamiento combinado quimioterápico y quirúrgico. Es importante tener presente estas raras aunque posibles localizaciones de linfomas para evitar que se puedan confundir con lesiones inflamatorias u otros tipos de tumores que nos lleven a un fracaso terapéutico. Abstract in english Primary non-Hodgkin lymphomas rarely involve the female genital tract (2% of primary extranodal lym-phomas). The ovaries followed by the cervix are the most common affected sites while the involvement of the endometrium and vagina is extremely rare. We report the case of a 44 year old woman with a p [...] rimary lymphoma of the vagina, stage IE A, with complete remission after combined chemotherapy and surgical treatment. These rare but possible locations must be kept in mind to avoid misdiagnosis with inflammatory lesions or other types of tumors which may lead us to a therapeutic failure.

  10. Small cell carcinoma of the vagina

    International Nuclear Information System (INIS)

    A case of localized small cell neuroendocrine carcinoma of the vagina is reported. The patient was treated with concurrent chemoradiation with significant toxicity but obtained a complete response. Thirteen months after therapy the patient developed distant metastasis and died shortly thereafter. Review of the literature found that patients treated with local therapy alone had a shorter survival and died of systemic disease. As with small cell neuroendocrine carcinomas arising from other sites, systemic relapse remains an important issue that warrants combination therapies, although in pelvic sites this may be associated with an increase in side-effects. Copyright (2000) Blackwell Science Pty Ltd

  11. Primary leiomyosarcoma of vagina: case report; Leiomiossarcoma primario de vagina: relato de caso

    Energy Technology Data Exchange (ETDEWEB)

    Vieira, Leonardo Jose [Hospital ASCONCER Associacao Feminina de Prevencao e Combate ao Cancer, Juiz de Fora, MG (Brazil). Servico de Cirurgia; Freitas, Rosyane Rena de [Juiz de Fora Univ., MG (Brazil). Faculdade de Medicina; Oliveira, Alexandre Ferreira de [Juiz de Fora Univ., MG (Brazil). Faculdade de Medicina. Disciplina de Cirurgia Gastroenterologica; Assis, Raimunda Violante Campos de [Juiz de Fora Univ., MG (Brazil). Faculdade de Medicina. Dept. de Patologia; Cugola, Elaine Aline; Costa, Sandra Marcia Carvalho Ribeiro

    2004-07-01

    Primary malignant lesions of the vagina are uncommon and represent about 1% of all gynecological malignancies. Most of these neoplasms are carcinomas. Sarcomas comprise less than 2% of all malignant vaginal tumours. In this present article, we describe a primary vaginal leiomyosarcoma in a 40-years-old woman. (author)

  12. vagina artificial, utilizando como estímulo objetos inanimados

    Directory of Open Access Journals (Sweden)

    Virginio Aguirre Flores

    2005-01-01

    Full Text Available Con el fi n de desarrollar una metodología para entrenar carneros en la recolección de semen con vagina artifi cial (VA, montando un objeto inanimado, se utilizaron nueve animales que se sometieron a cuatro etapas de preparación. La primera con el propósito de lograr la manifestación del repertorio sexual natural, y el resto para llevar a cabo un programa de condicionamiento operante: cuando la respuesta correcta (monta sucedía, en un inicio provocada por un estado de motivación sexual, se daba un refuerzo positivo o estímulo incondicionado (eyaculación, con lo que eventualmente y mediante un proceso de generalización la respuesta condicionada (primero montar a una hembra que no estaba en celo y luego a un objeto inanimado se aprendió como la respuesta correcta. Al inicio de cada fase 33%-55% de los carneros no eyacularon; sin embargo, al fi nal de las fases 1-3, todos eyacularon al menos una vez, al fi nal del entrenamiento fue imposible recolectar semen de un macho. Se concluye que mediante la metodología propuesta 90% de los machos jóvenes pueden ser entrenados para montar objetos inanimados con el fi n de recolectar semen mediante VA.

  13. Rare case of primary mucinous adenocarcinoma of vagina

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    Bharati Dhorepatil

    2013-01-01

    Full Text Available Here we present a rare case of primary mucinous adenocarcinoma of vagina treated successfully with wide local excision and post-operative radiotherapy. There was no recurrence even after four years.

  14. [Atopobium vaginae: characterization and association with pathogenesis of bacterial vaginosis].

    Science.gov (United States)

    Romanik, Ma?gorzata; Friedek, Daniela; Wojciechowska-Wieja, Anna; Martirosian, Gayane

    2006-05-01

    Atopobium vaginae was described in 1999 by Rodriguez et al. It is a Gram-positive bacterium producing organic acids (lactic acid, acetic acid, formic acid) as a results of glucose fermentation. It was first found in vaginal swab taken from a healthy woman using 16S rRNA analysis. A. vaginae is associated with bacterial vaginosis and its consequences in upper part of women reproductive organs. PMID:16958231

  15. Aggressive angiomyxoma of the vagina: a case report / Angiomiosarcoma agressivo da vagina: relato de caso

    Scientific Electronic Library Online (English)

    Cátia, Lourenço; Nuno, Oliveira; Filomena, Ramos; Isabel, Ferreira; Mário, Oliveira.

    2013-12-01

    Full Text Available O angiomixoma agressivo é tumor raro de tecidos moles, de lento crescimento e que geralmente ocorre na pelve e nas regiões perineais de mulheres em idade reprodutiva, com forte tendência à recorrência local. Devido à sua raridade, ele é frequentemente mal diagnosticado. A exerese cirúrgica é a modal [...] idade principal para o tratamento do angiomixoma agressivo. Descrevemos aqui um caso de angiomixoma vaginal agressivo em mulher de 47 anos de idade, que foi diagnosticado apenas após exame histológico. Descrevemos também a etiologia e apresentação, bem como o diagnóstico e tratamento desse raro tumor. O angiomixoma da vulva e vagina constitui doença rara. Devido à raridade desse tumor e à ausência de elementos diagnósticos, o diagnóstico pré-operatório é difícil, mas deveria ser considerado na presença de qualquer massa na região genital, perianal e pélvica de mulheres em idade reprodutiva. Portanto, esses casos deveriam ser submetidos a propedêutica radiológica completa antes da exerese, uma vez que um pré-diagnóstico pode modificar a modalidade de tratamento e o prognóstico do paciente. Abstract in english Aggressive angiomyxoma is a rare, slow-growing soft tissue tumor that usually arises in the pelvis and perineal regions of women in reproductive age, with a marked tendency to local recurrence. Because of its rarity, it is often initially misdiagnosed. Surgical resection is the main treatment modali [...] ty of aggressive angiomyxoma. We describe a case of a vaginal aggressive angiomyxoma in a 47-year-old woman in which the diagnosis was only made after histological examination. The etiology, presentation, diagnosis and management of this rare tumor are outlined. Angiomyxoma of vulva and vagina refers to a rare disease. Pre-operative diagnosis is difficult due to rarity and absence of diagnostic features, but it should be considered in every mass in genital, perianal and pelvic region in a woman in the reproductive age. Thus, these cases should have complete radiological workup before excision, as pre-diagnosis can change the treatment modality and patient prognosis'.

  16. Primary malignant melanoma of the vagina: a case report

    Energy Technology Data Exchange (ETDEWEB)

    Jang, Ji Young; Kim, Do Kang; Lee, Eun Hee [College of Medicine, Catholic Univ., Seoul (Korea, Republic of); Kim, Jun Sang [College of Medicine, Chungnam National Univ., Daejeon (Korea, Republic of)

    2003-09-01

    A primary malignant melanoma of the vagina is a very rare gynecological malignant tumor. Its clinical behavior is more aggressive than that of cutaneous and vulvar melanomas. We present a case of a large sized primary melanoma of the lower third of the vagina, with a cervical lesion, in a 58-year-old postmenopausal woman. The patient was treated with conventional external radiation therapy and intracavitary radiotherapy (lCR), without surgical treatment. Although the primary lesion showed a partial response, the patient died of extensive metastases, which were found 4.5 months after the initial diagnosis. We suggest that shortening the treatment period, such as hypofractionated radiation therapy and surgical removal, and various systemic therapies for preventing early distant metastasis, are appropriate treatments for a primary malignant melanoma of the vagina, with a large tumor size.

  17. MORPHOLOGICAL STUDY OF THE VAGINA OF THE Myocastor coypus (COYPU ESTUDIO MORFOLOGICO DE LA VAGINA DE Myocastor coypus (COIPO

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    Antonio E. Felipe

    2000-01-01

    Full Text Available The Myocastor coypus (coypu is a medium size rodent internationally considered as a species of economic interest because its fur. The aims of this work was realized the morphological study of the vagina of coypu. The vagina of sexually mature coypus appeared as a tubular organ, 10.25±1.40 cm long. The vaginal wall was very thin. It was composed by four layers: mucosa, submucosa, muscularis, and adventitia or serosa (according to the region. The lining epithelium of the mucosa was squamous stratified and without glands. Two layers of smooth muscular tissue with abundance of connective tissue were differentiated in the muscularis. The tunica serosa, formed by connective tissue of dense aspect, had numerous big blood vesselsMyocastor coypus es un roedor de tamaño mediano, considerado internacionalmente como una especie de interés económico por sus cualidades peleteras. El estudio morfológico de su vagina reviste importancia en el marco de investigaciones de su fisiología reproductiva. La vagina de coipos sexualmente maduros se presentó como un órgano tubular, de 10,25 ± 1,40 cm de longitud. La pared vaginal fue muy delgada, distinguiéndose en ella cuatro túnicas: mucosa, submucosa, muscular y adventicia o serosa (según la región. Su epitelio de revestimiento era de tipo escamoso estratificado y aglandular. En la túnica muscular se diferenciaron dos capas de tejido muscular liso con abundancia de tejido conectivo. La serosa, conformada por tejido conectivo de aspecto denso, presentó numerosos y grandes vasos sanguíneos

  18. Radiosterilisation of the vagina in therapeutic doses - does it exist

    International Nuclear Information System (INIS)

    The endogenous genital flora is a major source of infections of the female genital tract, especially in patients with cervical or endometrial cancer. Until recently the 'radiosterilisation of the vagina', respectively a prophylactic and/or therapeutic effect of irradiation (external highvoltage as well as intracavitary-radium) concerning infections was postulated in the literature. This theory was disproved in a prospective clinical and bacteriological study covering 48 patients with advanced cervical cancer undergoing primary intracavitary radium-irradiation and 38 patients with inoperable endometrical cancer, undergoing primary iridium-192-afterloading. Following intracavitary radium for cervical cancer some typical nosocomial pathogens like Streptococcus faecalis, Enterobacter, Klebsiella, Proteus and Pseudomonas were isolated significantly more frequently than before treatment. Likewise, the mean number of aerobic bacterial species increased significantly after irradiation. Also primary Ir-192 (afterloading) irradiation did not alter the frequency of isolation of the resident flora in endometrial cancer patients. Therefore, 'radiosterilisation' of the vagina as result of radiotherapy does not exist. (orig.)

  19. Management of radionecrosis of the vulva and distal vagina

    Energy Technology Data Exchange (ETDEWEB)

    Roberts, W.S.; Hoffman, M.S.; LaPolla, J.P.; Ruas, E.; Fiorica, J.V.; Cavanagh, D. (Univ. of South Florida, Tampa (USA))

    1991-05-01

    Twelve patients were seen between January 1983 and June 1989 with the clinical diagnosis of radionecrosis of the vulva or distal vagina. Seven patients received radiation for vulvar cancer, three for distal vaginal cancer, and two for recurrent endometrial cancer. No patient healed spontaneously and the mean delay in surgical therapy was 8.5 months. The radionecrotic site was treated with local therapy, radical local excision (with or without colostomy), or exenteration. The operative defect was closed primarily in three patients and covered with local flaps or myocutaneous flaps in seven patients. The two patients with local care still have radionecrotic ulcers. One of three patients who were closed primarily continues to have an ulcer. All other patients have healed satisfactorily except one who died after two attempts to correct the problem. Radionecrosis of the vulva and distal vagina should generally be treated surgically.

  20. Management of radionecrosis of the vulva and distal vagina

    International Nuclear Information System (INIS)

    Twelve patients were seen between January 1983 and June 1989 with the clinical diagnosis of radionecrosis of the vulva or distal vagina. Seven patients received radiation for vulvar cancer, three for distal vaginal cancer, and two for recurrent endometrial cancer. No patient healed spontaneously and the mean delay in surgical therapy was 8.5 months. The radionecrotic site was treated with local therapy, radical local excision (with or without colostomy), or exenteration. The operative defect was closed primarily in three patients and covered with local flaps or myocutaneous flaps in seven patients. The two patients with local care still have radionecrotic ulcers. One of three patients who were closed primarily continues to have an ulcer. All other patients have healed satisfactorily except one who died after two attempts to correct the problem. Radionecrosis of the vulva and distal vagina should generally be treated surgically

  1. Malignant peripheral nerve sheath tumor of the vagina

    International Nuclear Information System (INIS)

    Malignant peripheral nerve sheath tumors (MPNSTs) usually develop in major nerve trunks, giving rise to tumors in the proximal portions of the upper and lower extremities and trunk. The MPNSTs primarily occurring in the female genital tract are quite rare. We describe a case of MPNST of the vagina and discuss its diagnosis and treatment. This patient was treated definitively with radical local excision and is well with no signs of recurrence 2 years postoperatively. (author)

  2. Malignant peripheral nerve sheath tumor of the vagina.

    OpenAIRE

    Jie Zhang; Yang Sun; Zhi-lan Peng

    2009-01-01

    ABSTRACT Malignant peripheral nerve sheath tumors (MPNSTs) usually develop in major nerve trunks, giving rise to tumors in the proximal portions of the upper and lower extremities and trunk. The MPNSTs primarily occurring in the female genital tract are quite rare. We describe a case of MPNST of the vagina and discuss its diagnosis and treatment. This patient was treated definitively with radical local excision and is well with no signs of recurrence 2 years postoperatively.

  3. Management of radiation injuries of vulva and vagina

    Energy Technology Data Exchange (ETDEWEB)

    Fraunholz, I.B.; Schopohl, B.; Boettcher, H.D. [Klinik fuer Strahlentherapie und Onkologie, Johann-Wolfgang-Goethe-Universitaet Frankfurt am Main (Germany)

    1998-11-01

    Background: Acute and late injuries of vulva and vagina are frequent and potentially serious complications in radiotherapy of gynecologic tumors. They still are reported poorly in literature. Methods: Based on a literature search a survey will be given of the modalities, which are used or recommended for prophylaxis or treatment of these radiation injuries. The principles of the different measures will be discussed with available study results. Results: Hygiene measures and the topical application of antimicrobial or granulation stimulating substances, which is mostly based on long standing clinical experience, are the principles of the treatment of acute reactions of vulva and vagina. The topical use of estrogen, which promotes proliferation of epithelium, is generally described in connection with treatment and prophylaxis of late radiation injuries. As a prophylaxis for the late reaction of vaginal stenosis, vaginal dilatation is recommended in literature. Conclusion: With the exception of a few reports on estrogen, there are no data about the effectiveness of the currently used medical substances. The local application of estrogen as prophylaxis of the acute reactions will therefore be examined in a prospective study. (orig.) [Deutsch] Hintergrund: Akute und spaete Reaktionen an Vulva und Vagina sind haeufige und zum Teil schwerwiegende Nebenwirkungen der Strahlentherapie von gynaekologischen Tumoren, auf die in der Literatur kaum eingegangen wird. Methoden: Basierend auf einer umfangreichen Literaturrecherche, werden die Massnahmen, die zur Prophylaxe oder Therapie dieser Strahlenreaktionen zur Verfuegung stehen, systematisch zusammengestellt und, soweit verfuegbar, mit Ergebnissen aus Studien diskutiert. Ergebnisse: Hygienemassnahmen und die auf klinischen Erfahrungswerten basierende lokale Anwendung einer Vielzahl von mehr oder weniger antimikrobiell wirkenden oder granulationsfoerdernden Substanzen lassen sich als Grundprinzipien der Behandlung von akuten Reaktionen an Vulva und Vagina erkennen. Der Einsatz von lokalen Oestrogenapplikationen, die die hormonabhaengige Proliferation des Epithels ausnutzen, wird ueberwiegend im Zusammenhang mit Therapie und Prophylaxe von radiogenen Spaetfolgen beschrieben. Als eine Art der Prophylaxe von Spaetreaktionen in Form der Vaginalstenose hat sich die Empfehlung der vaginalen Dilatation etabliert. Schlussfolgerungen: Mit Ausnahme von einigen Arbeiten zu Oestrogen gibt es keine Daten ueber die Wirksamkeit der eingesetzten Substanzen. Die lokale Oestrogenapplikation zur Prophylaxe der akuten Strahlenreaktionen wird daher in einer prospektiven Studie untersucht werden. (orig.)

  4. KANDIDIASIS VAGINA YANG MENDAPAT TERAPI SISTEMIK DAN TOPIKAL: SEBUAH LAPORAN KASUS

    Directory of Open Access Journals (Sweden)

    Dewa Made Rendy Sanjaya

    2014-08-01

    Full Text Available Kandidiasis vulvovaginitis ialah penyakit jamur candida yang mengenai mukosa vagina danvulva.Penyebabnya yang tersering biasanya adalah candida albicans.Gejala klinis KandidiasisVulvovaginitis ialah gatal didaerah vulva, dan pada yang berat terdapat rasa panas,dispaneuria.lesi eritema, hiperemis dilabia mayora, dan vagina 1/3 bawah. Dilaporkan satu  kasusseorang wanita. berumur 26 tahun dengan keluhan keputihan pada daerah vagina sertamengalami kegatalan dan rasa nyeri terjadi sejak 2 minggu yang lalu. Pada gambaran klinis tampak dinding vagina eritema, erosi dengan secret putih kental. Pada pengecatan gram darisecret mukosa vagina didapatkan leukosit blastopsora dan pseudohifa. Pemerikaan KOH 10%dari sekret vagina didapatkan blastopore dan pesudohifa.Penanganan yang diberikan adalah obatsistemik dengan flukonazol 1x150 mg dosis tunggal dan topical diberikan ketokenazol cream.Prognosis kasus tersebut adalah baik..

  5. Management of radiation injuries of vulva and vagina

    International Nuclear Information System (INIS)

    Background: Acute and late injuries of vulva and vagina are frequent and potentially serious complications in radiotherapy of gynecologic tumors. They still are reported poorly in literature. Methods: Based on a literature search a survey will be given of the modalities, which are used or recommended for prophylaxis or treatment of these radiation injuries. The principles of the different measures will be discussed with available study results. Results: Hygiene measures and the topical application of antimicrobial or granulation stimulating substances, which is mostly based on long standing clinical experience, are the principles of the treatment of acute reactions of vulva and vagina. The topical use of estrogen, which promotes proliferation of epithelium, is generally described in connection with treatment and prophylaxis of late radiation injuries. As a prophylaxis for the late reaction of vaginal stenosis, vaginal dilatation is recommended in literature. Conclusion: With the exception of a few reports on estrogen, there are no data about the effectiveness of the currently used medical substances. The local application of estrogen as prophylaxis of the acute reactions will therefore be examined in a prospective study. (orig.)

  6. Definitive radiation therapy for squamous cell carcinoma of the vagina

    International Nuclear Information System (INIS)

    Purpose: To evaluate outcome and describe clinical treatment guidelines for patients with primary squamous cell carcinoma of the vagina treated with definitive radiation therapy. Methods and Materials: Between 1970 and 2000, a total of 193 patients were treated with definitive radiation therapy for squamous cell carcinoma of the vagina at The University of Texas M. D. Anderson Cancer Center. The patients' medical records were reviewed to obtain information about patient, tumor, and treatment characteristics, as well as outcome and patterns of recurrence. Surviving patients were followed for a median of 137 months. Survival rates were calculated using the Kaplan-Meier method, with differences assessed using log-rank tests. Results: Disease-specific survival (DSS) and pelvic disease control rates correlated with International Federation of Gynecology and Obstetrics (FIGO) stage and tumor size. At 5 years, DSS rates were 85% for the 50 patients with Stage I, 78% for the 97 patients with Stage II, and 58% for the 46 patients with Stage III-IVA disease (p = 0.0013). Five-year DSS rates were 82% and 60% for patients with tumors ?4 cm or >4 cm, respectively (p = 0.0001). At 5 years, pelvic disease control rates were 86% for Stage I, 84% for Stage II, and 71% for Stage III-IVA (p = 0.027). The predominant mode of relapse after definitive radiation therapy was local-regional (68% and 83%, respectively, for patients with stages I-II or III-IVA disease). The incidence of major complications was correlated with FIGO stage; at 5 years, the rates of major complications were 4% for Stage I, 9% for Stage II, and 21% for Stage III-IVA (p < 0.01). Conclusions: Excellent outcomes can be achieved with definitive radiation therapy for invasive squamous cell carcinoma of the vagina. However, to achieve these results, treatment must be individualized according to the site and size of the tumor at presentation and the response to initial external-beam radiation therapy. Brachytherapy plays an important role in the treatment of many vaginal cancers but should be carefully selected and applied to obtain optimal coverage of the target volume

  7. Inseminación artificial de alpacas con semen colectado por aspiración vaginal y vagina artificial / Artificial insemination of alpacas with semen collected by vaginal aspiration and by artificial vagina

    Scientific Electronic Library Online (English)

    Virgilio, Alarcón B; Wilber, García V; P. Walter, Bravo.

    Full Text Available Semen de alpaca fue colectado por dos métodos: por aspiración de la vagina de la hembra después de la monta natural y con vagina artificial. El semen colectado fue evaluado y diluido con Tris tamponado, y luego usado en inseminacion artificial. Se trabajó con 160 alpacas hembras adultas de capacidad [...] reproductiva comprobada y 5 alpacas machos. Se colectó semen post cópula de los cinco machos en 10 hembras, y se hicieron 50 colecciones de semen con vagina artificial de estos machos, dos veces por semana. Se determinó volumen, motilidad, concentración espermática, porcentaje de espermatozoides vivos, viscosidad y color. Los resultados para semen colectado por aspiración de la vagina y con vaginal artificial fueron: volumen (3.6 y 1.5 mL), motilidad (73.4 y 69.0%), concentración espermática (75.2 y 80.3 millones/mL), espermatozoides vivos (75.3 y 70.8%), respectivamente, con diferencia entre métodos (p Abstract in english Semen from alpacas was collected by two methods: by aspiration from the female’s vagina following mating and with an artificial vagina. Semen was collected, evaluated and extended with Tris buffer, and then used in artificial insemination. Altogether 160 female alpacas with proven reproductive histo [...] ry and five males were used. Semen was collected by vaginal aspiration from 10 females using five males as semen donors; likewise, semen from the same males was collected with an artificial vagina twice a week 50 times. Volume, motility, spermatic concentration, live spermatozoa, viscosity and color was evaluated. Seminal characteristics of semen collected by aspiration and with an artificial vagina were: volume (3.6 and 1.5 mL), motility (73.4 and 69.0%), sperm concentration (75.2 and 80.3 million/mL), live spermatozoa (75.3 and 70.8%) respectively, with statistical difference between methods (p

  8. Malignant melanoma of the vagina: a report of 2 cases

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Ok Bae; Kim, Jin Hee; Jung, Young Yeon; Cho, Chi Heum; Choi, Tae Jin [Dongsan Medical Center, School of Medicine, Keimyung University, Daegu (Korea, Republic of)

    2005-06-15

    Primary malignant melanoma of the vagina is an extremely rare genital neoplasm occurring mainly in postmenopausal women. It has a worse prognosis than cutaneous melanomas, because of the high rate of locoregional recurrences and rapid systemic dissemination. In the past, radical surgical extirpation as the primary management had been recommended to improve loco-regional control, and possibly overall survival. However, the prognosis was poor in spite of such a radical approach. Recently, more conservative treatment such as wide local excision combined with adjuvant high-dose fraction radiotherapy seems to have promising results. Primary radiation therapy could be served as an alternative to surgery for patients with lesion less than 3 cm in diameter. We report 2 cases of primary vaginal malignant melanoma treated with radiotherapy.

  9. Almacenamiento de espermatozoides en la vagina de la lagartija vivípara Sceloporus torquatus (Sauria: Prhynosomatidae) / Sperm storage in the vagina of the viviparous lizard Sceloporus torquatus (Sauria: Prhynosomatidae)

    Scientific Electronic Library Online (English)

    Martín, MARTÍNEZ-TORRES.

    2009-12-01

    Full Text Available Las hembras de muchas especies de lagartijas tienen la capacidad de almacenar espermatozoides en un sistema de túbulos especiales presentes en la vagina. Sin embargo, en otras especies los espermatozoides se almacenan en el infundíbulo. Se utilizó una técnica sencilla y rápida para determinar sí la [...] vagina de Sceloporus torquatus tiene la capacidad de almacenar espermatozoides. En las hembras de esta especie, los espermatozoides son retenidos al menos 167 días en un sistema de túbulos especiales localizados en la vagina. La cantidad de espermatozoides presentes en los lavados vaginales disminuyó gradualmente a partir de diciembre y su desaparición ocurrió en la preñez tardía. Los espermatozoides ascienden al útero e infundíbulo antes de que ocurra la ovulación, sin embargo, en estos órganos no existen estructuras especiales para almacenar espermatozoides. Abstract in english Females of many lizard species are able to store sperm in a special system of tubules present in the vagina. However, in other species sperm storage occurs in the infundibulum. A quick and simple technique to determine if the vagina of Sceloporus torquatus has the capacity to store sperm was used. I [...] n this species the spermatozoa are retained at least during 167 days after mating in a special system of tubules located in the vagina. The amount of spermatozoa observed through vaginal flushing was reduced gradually from December on and the spermatozoa disappeared in late pregnancy. The spermatozoa reached the uterus and infundibulum before ovulation started; however, in these organs there are no special structures for sperm storage.

  10. Primary Small Cell Neuroendocrine Carcinoma of Vagina: A Rare Case Report

    OpenAIRE

    Malay N. Parekh; Dhiren V. Kapapura; Jignasa N Bhalodia

    2011-01-01

    Primary small cell neuroendocrine carcinoma of vagina is an extremely rare disease. There have been only 26 previously reported cases in literature. Here, we report a case of primary small cell neuroendocrine carcinoma of vagina. Immunohistochemistry (IHC) showed tumor cells positive for synaptophysin, chromogranin, and neuron-specific enolase (NSE).

  11. Radiation-induced morphological changes in the vagina

    Energy Technology Data Exchange (ETDEWEB)

    Kirchheiner, K.; Fidarova, E.; Schmid, M.P.; Sturdza, A.; Kranz, A.; Poetter, R. [Medical Univ. of Vienna (Austria). Dept. of Radiation Oncology; Nout, R.A. [University Medical Center Leiden (Netherlands). Dept. of Clinical Oncology; Wiebe, E. [Alberta Univ., Cross Cancer Institute, Edmonton, AB (Canada). Dept. of Radiation Oncology; Polterauer, S. [Medical Univ. of Vienna (Austria). Dept. of General Gynecology and Gynecologic Oncology; Doerr, W. [Medical Univ. of Vienna (Austria). Dept. of Radiation Oncology; Medical Univ. of Vienna (Austria). Christian Doppler Laboratory for Medical Radiation Research for Radiation Oncology

    2012-11-15

    Background and purpose: Treatment-induced chronic vaginal changes after definitive radio(chemo)therapy for locally advanced cervical cancer patients are reported as one of the most distressing consequences of treatment, with major impact on quality of life. Although these vaginal changes are regularly documented during gynecological follow-up examinations, the classic radiation morbidity grading scales are not concise in their reporting. The aim of the study was therefore to identify and qualitatively describe, on the basis of vaginoscopies, morphological changes in the vagina after definitive radio(chemo)therapy and to establish a classification system for their detailed and reproducible documentation. Patients and methods: Vaginoscopy with photodocumentation was performed prospectively in 22 patients with locally advanced cervical cancer after definitive radio(chemo)therapy at 3-24 months after end of treatment. All patients were in complete remission and without severe grade 3/4 morbidity outside the vagina. Results: Five morphological parameters, which occurred consistently after treatment, were identified: mucosal pallor, telangiectasia, fragility of the vaginal wall, ulceration, and adhesions/occlusion. The symptoms in general were observed at different time points in individual patients; their quality was independent of the time of assessment. Based on the morphological findings, a comprehensive descriptive and semiquantitative scoring system was developed, which allows for classification of vaginal changes. A photographic atlas to illustrate the morphology of the alterations is presented. Conclusion: Vaginoscopy is an easily applicable, informative, and well-tolerated procedure for the objective assessment of morphological vaginal changes after radio(chemo)therapy and provides comprehensive and detailed information. This allows for precise classification of the severity of individual changes. (orig.)

  12. Radiation-induced morphological changes in the vagina

    International Nuclear Information System (INIS)

    Background and purpose: Treatment-induced chronic vaginal changes after definitive radio(chemo)therapy for locally advanced cervical cancer patients are reported as one of the most distressing consequences of treatment, with major impact on quality of life. Although these vaginal changes are regularly documented during gynecological follow-up examinations, the classic radiation morbidity grading scales are not concise in their reporting. The aim of the study was therefore to identify and qualitatively describe, on the basis of vaginoscopies, morphological changes in the vagina after definitive radio(chemo)therapy and to establish a classification system for their detailed and reproducible documentation. Patients and methods: Vaginoscopy with photodocumentation was performed prospectively in 22 patients with locally advanced cervical cancer after definitive radio(chemo)therapy at 3-24 months after end of treatment. All patients were in complete remission and without severe grade 3/4 morbidity outside the vagina. Results: Five morphological parameters, which occurred consistently after treatment, were identified: mucosal pallor, telangiectasia, fragility of the vaginal wall, ulceration, and adhesions/occlusion. The symptoms in general were observed at different time points in individual patients; their quality was independent of the time of assessment. Based on the morphological findings, a comprehensive descriptive and semiquantitative scoring system was developed, which allows for classification of vaginal changes. A photographic atlas to illustrate the morphology of the alterations is presented. Conclusion: Vaginoscopy is an easily applicable, informative, and well-tolerated procedure for the objective assessment of morphological vaginal changes after radio(chemo)therapy and provides comprehensive and detailed information. This allows for precise classification of the severity of individual changes. (orig.)

  13. High-dose-rate brachytherapy for cervical carcinoma patients with narrow vagina

    Energy Technology Data Exchange (ETDEWEB)

    Yorozu, Atsunori; Toya, Kazuhito; Kawase, Takatugu [National Tokyo Medical Center, Tokyo (Japan); Dokiya, Takushi [Saitama Medical Coll., Moroyama (Japan)

    2002-06-01

    We retrospectively analyzed cervical cancer patients with narrow vagina treated by high-dose-rate (HDR) brachytherapy followed by external beam irradiation. Fifty patients were treated with radical radiotherapy between 1992 and 1999 at the National Tokyo Medical Center. All patients received 30 Gy of external whole pelvic irradiation and 20 Gy of pelvic irradiation with a central shield. After 30 Gy of whole pelvic irradiation, 24 Gy of fractionated brachytherapy was applied with a tandem and ovoids, non-rigid type developed in the Cancer Institute, according to the Manchester method. Nineteen patients with a narrow vagina of less than 40 mm in width were compared with 31 other patients (control group). The 5-year cumulative survival rates were 56% in the patients with a narrow vagina and 53% in the control group (P=0.6008). The control rate in the pelvis was not significantly different between the two groups. The cumulative rate of rectal complications of the patients with a narrow vagina was more frequent than the control group (58% vs 29%) (P=0.0924). Severe rectal bleeding was also more frequent in the patients with a narrow vagina. The estimated maximal dose of the rectal wall was significantly higher in patients with a narrow vagina. This result suggests that a lower brachytherapy dose is necessary for patients with narrow vagina considering the rectal sequelae in the case of using our methods. (author)

  14. The vagina as a route for drug delivery: a review.

    Science.gov (United States)

    Srikrishna, Sushma; Cardozo, Linda

    2013-04-01

    Overactive bladder (OAB) syndrome has a significant deleterious impact on quality of life. After conservative therapy and bladder retaining, antimuscarinic drugs remain the mainstay of OAB management. Oral therapy is associated with frequent side effects, leading to the development of alternative agents and formulations or the use of novel routes of drug administration, such as the vaginal route. The vagina is often ideal for drug delivery because it allows the use of lower doses, maintains steady drug administration levels, and requires less frequent administration than the oral route. With vaginal drug administration, absorption is unaffected by gastrointestinal disturbances, there is no first-pass effect, and use is discreet. The aim of this review is to provide a background overview of vaginal development, anatomy, and physiology and the effect this has on the use of this route for both local and systemic drug delivery, with special reference to OAB management. Vaginal therapy continues to be an underused route of drug delivery. Vaginal administration allows nondaily, low, continuous dosing, which results in stable drug levels and may, in turn, achieve a lower incidence of side effects and improve patient compliance. These benefits must be balanced against inherent patient or physician bias against using this route and the need to overcome cultural, personal, and hygiene-related barriers to this form of therapy. More sophisticated and programmable vaginal rings are being developed for systemic delivery of therapeutically important macromolecules, such as antimuscarinic therapy in OAB management. PMID:23229421

  15. Congenital absence of the vagina with a functioning uterus

    International Nuclear Information System (INIS)

    A functioning uterus may be present in 5 to 10 % of the patients with congenital absence of the vagina. The proper treatment for these patients depends on accurate pre-operative diagnosis on whether or not a cervix is present, because the mode of operation should be selected according to the type of abnormality. Ultrasonography or X-ray CT scan will not always be useful to answer this question. We encountered a 15-year-old female with cyclic lower abdominal pain and the failure of onset of menstruation. The external genitalia were normal except for the absence of the vaginal opening. Ultrasonography and X-ray CT scan revealed the presence of both uterine corpus and hematocolpos, but no definite findings were obtained on the integrity of the cervix. By using NMR-CT scan, we found a hematocolpos, properly developed uterine cervix and corpus above it. We treated the patient by preserving the uterine function and the potential for pregnancy in the future. NMR-CT scan seems more useful in some cases for diagnosis of pelvic mass than ultrasonography and X-ray CT scan. (author)

  16. Results of radiation therapy of squamous cell carcinoma of vagina

    Energy Technology Data Exchange (ETDEWEB)

    Tsukiyama, Iwao; Kakehi, Masae; Ono, Ryosuke (National Cancer Center, Tokyo (Japan). Hospital)

    1984-06-01

    Over a period from 1962 to 1982, 31 patients with squamous cell carcinoma in the vagina were treated by irradiation at National Cancer Center Hospital, Tokyo. Of them, 15 patients (48.4%) were over 60 years old. Treatment was done by external irradiation alone or a combination of external and intracavitary or interstitial irradiation. The lesions were classified into stages of the FIGO system. Stage I was found in 11 cases (35.5%), Stage II in 11 cases (35.5%), Stage III in 7 cases (22.6%) and Stage IVa in 1 case (3.2%). Serious complication after treatment was observed in 5 cases (16.1%) which consisted of 2 cases of rectovaginal fistula and one case of rectal constriction, one case of intestinal necrosis and one case of rectal ulcer. Local and pelvic failure was noted in 6 cases (19.4%) which were treated by reirradiation. Prognosis was poor in all cases, except one which was in Stage I. Some subsequent surgical procedures were required for further treatment in those cases. The 5-year survival rates by stage were as follows: 90% (9/10) for cases of Stage I, 22.2% (2/9) for cases of Stage II, 16.7% (1/6) for cases of Stage III and 0% (0/1) for case of Stage IVa.

  17. Results of radiation therapy of squamous cell carcinoma of vagina

    International Nuclear Information System (INIS)

    Over a period from 1962 to 1982, 31 patients with squamous cell carcinoma in the vagina were treated by irradiation at National Cancer Center Hospital, Tokyo. Of them, 15 patients (48.4%) were over 60 years old. Treatment was done by external irradiation alone or a combination of external and intracavitary or interstitial irradiation. The lesions were classified into stages of the FIGO system. Stage I was found in 11 cases (35.5%), Stage II in 11 cases (35.5%), Stage III in 7 cases (22.6%) and Stage IVa in 1 case (3.2%). Serious complication after treatment was observed in 5 cases (16.1%) which consisted of 2 cases of rectovaginal fistula and one case of rectal constriction, one case of intestinal necrosis and one case of rectal ulcer. Local and pelvic failure was noted in 6 cases (19.4%) which were treated by reirradiation. Prognosis was poor in all cases, except one which was in Stage I. Some subsequent surgical procedures were required for further treatment in those cases. The 5-year survival rates by stage were as follows: 90% (9/10) for cases of Stage I, 22.2% (2/9) for cases of Stage II, 16.7% (1/6) for cases of Stage III and 0% (0/1) for case of Stage IVa. (author)

  18. Lesson learned and dispelled myths: three-dimensional imaging of the human vagina.

    Science.gov (United States)

    Barnhart, Kurt T; Pretorius, E Scott; Malamud, Daniel

    2004-05-01

    Three-dimensional imaging of the human vagina demonstrates that the cross section can be a "W," rather than an "H," and that intravaginal gel can ascend into the endocervix and presumably into the endometrium. PMID:15136106

  19. Incarcerated foreign body in the vagina – a metal bangle used as a pessary

    OpenAIRE

    Dasari, Papa; Sagili, Haritha

    2012-01-01

    Long-forgotten vaginal pessaries get incarcerated in the vagina and their removal poses problems. A 60-year-old postmenopausal woman presented with foul smelling purulent discharge per vaginum and stress incontinence. Speculum examination revealed foul smelling white discharge per vaginum and a friable vaginal wall which bled on touch. The anterior portion of a metal ring deeply embedded in the vagina was seen. The cervix appeared normal. Attempts of removal by traction under local infiltrati...

  20. LASER EN EL TRATAMIENTO DE LA NEOPLASIA INTRAEPITELIAL DE VAGINA

    Scientific Electronic Library Online (English)

    Roberto, Yazigi I; Tulio, Rodríguez A; Luis, Contreras M.

    Full Text Available Objetivo: Presentar la experiencia en el tratamiento de la neoplasia intraepitelial de vagina (VAIN) utilizando el láser de CO2. Método: 19 pacientes con el diagnóstico histológico de VAIN fueron tratadas con esta técnica. Se utilizó un diámetro del punto de helio-neón de 1,5 a 2 mm y un poder de de [...] nsidad de 400 a 500 W/cm². Toda la lesión detectable más un margen de al menos 5 mm de tejido circundante aparentemente normal fueron vaporizados a una profundidad de 2 mm. Resultados: 12 de las 14 pacientes evaluables lograron una respuesta completa inicial (86%), de éstas 12 hubo 2 recidivas posteriores (17%), obteniendo una curación en 10 de las 14 evaluables (71%). No hubo complicaciones y se preservó una función vaginal normal. Conclusión: La vaporización con láser es una buena modalidad terapéutica en VAIN, particularmente en mujeres jóvenes en que se ha descartado razonablemente la coexistencia de cáncer invasor Abstract in english Objective: To describe our experience in the treatment of vaginal intra-epithelial neoplasia (VAIN) with the use of CO2 laser. Method: Nineteen patients with the diagnosis of VAIN were treated by this technique. We used a spot size of 1.5 to 2 mm and a power density of 400 to 500 W/cm². The entire l [...] esion in addition to at least a 5 mm margin of adjacent tissue were vaporized to a depth of 2 mm. Results: 12 of 14 evaluable patients had an initial complete response (86%), of these 12, there were 2 recurrences (17%), obtaining a 71% cure rate (10/14). There were no complications and preservation of normal vaginal function. Conclusion: Laser vaporization is a very good treatment modality, particularly in young women in whom the co-existence of invasive malignancy has been ruled out

  1. Contrast vaginography is more accurate than the radiopaque rod for localization of the vagina

    International Nuclear Information System (INIS)

    Purpose: To compare the radiopaque vaginal rod method with contrast vaginography in localization of the vagina. Methods and Materials: In 25 female patients who needed pelvic radiotherapy, both our standard localization procedure using the vaginal rod and a localization procedure using contrast vaginography were performed. As a rod can change the position of the vagina, contrast vaginography was considered to display the true anatomic position of the vagina. The corresponding rod and nonrod X-rays of each patient were compared. The distance from the true vaginal apex to the displaced vaginal apex (= the top of the rod) was measured in the sagittal plane. This distance was called the inaccuracy of the rod method. Furthermore, the size of the vaginal vault was measured using the contrast vaginography. Results: The median inaccuracy of the rod method was 13 mm (range 2 to 24 mm). The maximal width of the vagina ranged from 24 to 68 mm in the frontal plane (median 39 mm) and from 3 to 22 mm in the sagittal plane (median 10 mm). Conclusion: The rod method is not accurate to localize the vagina. Furthermore, the rod gives no information on the actual size of the vaginal vault. Contrast vaginography is the method of choice to localize the vagina.

  2. Longitud de vagina, hiato genital y cuerpo perineal en mujeres nulíparas / Lengh of vagina, genital hiatus and perineal body in nulliparae

    Scientific Electronic Library Online (English)

    Fernando, Méndez.

    2015-01-01

    Full Text Available Objetivo: Estimar la longitud promedio de vagina, del hiato genital y cuerpo perineal en mujeres nulíparas. Diseño: Estudio descriptivo transversal con muestreo por conveniencia. Institución: Departamento de Ginecología y Obstetricia, Hospital Nacional Cayetano Heredia, Lima, Perú. Participantes: Mu [...] jeres nulíparas. Métodos: En 85 mujeres nulíparas atendidas en el Hospital entre enero y marzo 2014, en edad fértil, que habían iniciado relaciones coitales vaginales y que requerían evaluación ginecológica, se realizó medición del peso y talla. En posición de litotomía, se midió con un hisopo milimetrado la longitud total de la vagina, hiato genital y el cuerpo perineal. Las mediciones fueron realizadas por un solo examinador. La participación fue completamente voluntaria y con firma de consentimiento informado. Principales medidas de resultados: Longitud total de la vagina, hiato genital y el cuerpo perineal. Resultados: La media de la longitud total de vagina fue 8,1 ± 1,4 cm (DE), del hiato genital 2,2 ± 0,5 cm (DE) y del cuerpo perineal 2,3 ± 0,5 cm (DE). Conclusiones: Las medidas estimadas no difieren con resultados de estudios internacionales. Se requiere estudiar una mayor muestra de pacientes de las diferentes regiones para tener un estimado más representativo de estas medidas en pacientes nulíparas del Perú. Abstract in english Objectives: To determine vaginal, genital hiatus and perineal body length in nulliparous women. Design: Cross-sectional descriptive study with convenience sample. Setting: Department of Obstetrics and Gynecology, Hospital Nacional Cayetano Heredia, Lima, Peru. Participants: Nulliparous women. Method [...] s: From January through March 2014 in 85 nulliparous women in childbearing age who had coital sex and required gynecological evaluation, weight and height were obtained and length of vagina, genital hiatus and perineal body were measured with a graph swab in lithotomy position. Measurements were obtained by one single examiner. Participation was voluntary with signed informed consent. Main outcome measures: Length of vagina, genital hiatus and perineal body. Results: Average length of patients’ vagina was 8.1 ± 1.4 cm (SD), genital hiatus 2.2 ± 0.5 cm (SD), and perineal body 2.3 ± 0.5 cm (SD). Conclusions: Measures obtained did not differ from international studies. A broad population study is suggested to better estimate these measures in nulliparous Peruvian women.

  3. Endodermal sinus tumor of the vagina in children: A report of two cases

    Directory of Open Access Journals (Sweden)

    Gangopadhyay Mimi

    2009-07-01

    Full Text Available Malignant tumors of the vagina in infants and children are rare, with primary germ cell tumor (endodermal sinus tumor [EST] being rarer, which carries a dismal prognosis. This tumor is often clinically mistaken as botryoid rhabdomyosarcoma and, on histopathological examination, is often misdiagnosed as clear cell adenocarcinoma. Two cases of EST of the vagina in infants aged 9 and 17 months are reported. Both the patients presented with bleeding per vagina and clinically and by ultrasonography were diagnosed as sarcoma botryoides. Both were diagnosed as primary yolk sac tumors. The serum alfa fetoprotein (AFP level was 4325 and 9328 ng/ml, respectively. One patient aged 9 months expired 2 months after receiving chemotherapy. The other, aged 17 months, was given chemotherapy followed by surgery with reduction of the AFP levels.

  4. Pathomorphologic Investigations on the Genital System of Ewes II.Uterus, Cervix and Vagina

    OpenAIRE

    KARADA?, Erkan; T?MURKAAN, Necati

    2001-01-01

    This study was carried out to determine the pathomorphologic changes and the incidence of these changes in the uterus, cervix, vagina and related ligaments of ewes slaughtered at Elaz?? abattoirs. For this purpose,the genital organs of 6100 ewes from different breeds and ages were examined.There were pathomorphologic changes in 274 cases (4.49%)in the uterus,70 cases (1.14%)in the cervix,and 61 cases (1.00%)in the vagina.Inflammatory changes were primarily lesions (2.68%)observed in the u...

  5. Carcinoma of the vulva and vagina in patients irradiated for carcinoma of the cervix

    International Nuclear Information System (INIS)

    Six patients with carcinoma of the vulva and 3 with carcinoma of the vagina following radiation therapy for cancer of the cervix were analyzed. The interval between irradiation and diagnosis of the second tumor varied from 5 to 23 years. Despite the lack of having detailed information on irradiation factors in all patients, circumstantial evidence from this study suggests that radiation therapy may have contributed to the development of carcinoma of the vulva and vagina in some of the patients. Close follow-up patients treated for squamous carcinoma of the genital tract must emphasize inspection for new lesions. The incidences previously reported in the literature are also reviewed for comparison. (author)

  6. Carcinoma of the vulva and vagina in patients irradiated for carcinoma of the cervix

    Energy Technology Data Exchange (ETDEWEB)

    Tsukiyama, Iwao; Kakehi, Masae; Ono, Ryosuke; Watai, Kiichi; Yanagawa, Shigeo; Kasamatsu, Tatsuhiro

    1984-08-01

    Six patients with carcinoma of the vulva and 3 with carcinoma of the vagina following radiation therapy for cancer of the cervix were analyzed. The interval between irradiation and diagnosis of the second tumor varied from 5 to 23 years. Despite the lack of having detailed information on irradiation factors in all patients, circumstantial evidence from this study suggests that radiation therapy may have contributed to the development of carcinoma of the vulva and vagina in some of the patients. Close follow-up patients treated for squamous carcinoma of the genital tract must emphasize inspection for new lesions. The incidences previously reported in the literature are also reviewed for comparison. (author).

  7. A longitudinal study of Staphylococcus hyicus colonization of vagina of gilts and transmission to piglets

    DEFF Research Database (Denmark)

    Wegener, Henrik Caspar; Skov Jensen, E.W.

    1992-01-01

    typing, as well as characterization of about 10 % of the isolates by plasmid profiles and antibiogram patterns, showed that, several different clones of S. hyicus could be present simultaneously in vagina of gilts and also on skin of piglets. Generally isolates from the vagina of one animal were...... identical as regards to phage types, plasmid profiles, and antibiogram patterns during the entire investigation period. Isolates from the skin of piglets were of the same type as their mothers, indicating that vertical transmission had taken place. S. hyicus strains isolated from the skin of piglets within...

  8. Imaging of the vagina and vulva; Aspectos de imagem das lesoes vulvo-vaginais

    Energy Technology Data Exchange (ETDEWEB)

    Souza, Luis Ronan Marquez Ferreira de; Szejnfeld, Jacob [Universidade Federal de Sao Paulo (UNIFESP/EPM), SP (Brazil). Dept. de Diagnostico por Imagem]. E-mail: luisronan@gmail.com; Borges, Leonardo Romualdo; Rosalen Junior, Roberto Antonio [Universidade Federal do Triangulo Mineiro (UFTM), Uberaba, MG (Brazil); Signorini Filho, Roney Cesar; Marques, Renato Moretti; Nicolau, Sergio Mancini [Universidade Federal de Sao Paulo (UNIFESP/EPM), SP (Brazil). Disciplina de Oncoginecologia; Goldman, Suzan Menasce [Universidade Federal de Sao Paulo (UNIFESP/EPM), SP (Brazil). Dept. de Diagnostico por Imagem

    2006-10-15

    In gynecological daily practices, the vulva and vagina are examined during physical examination, however there are situations where this is not possible or it is needed to determine the extension of an injury through imaging methods. The magnetic resonance imaging is an excellent cross-sectional modality for evaluation the alterations of vulva and vagina due its multiplanar evaluation and high tecidual contrast. Other cross-sectional modalities are ultrasound and enhanced computed tomography. This paper intends to give an overview of vaginal and vulvar pathology that can be identified by the radiologist. (author)

  9. Melanoma amelanótico primario de vagina: reporte de un caso y revisión de la literatura / Primary amelanotic melanoma of the vagina: a case report and literature review

    Scientific Electronic Library Online (English)

    María Paula, Houghton-Martínez; Jairo, Amaya-Guío; Luz Amparo, Díaz-Cruz.

    2012-03-01

    Full Text Available Objetivo: revisar el diagnóstico clínico, histológico e inmunohistoquímico; las alternativas terapéuticas y los factores que influyen en el pronóstico del melanoma amelanocítico de vagina. Materiales y métodos: se presenta el caso de una paciente de 49 años que consultó por masa vaginal de 8 cm en p [...] ared anterior de vagina, nacarada y con fondo necrótico a la Unidad de Patología Cervical y Colposcopia del Hospital de Engativá, institución de segundo nivel de complejidad que atiende pacientes de nivel socioeconómico bajo afiliados al régimen de seguridad pública. Se realizó resección amplia de la lesión. La patología quirúrgica informó melanoma fusocelular y epiteloide maligno. Se realizó una búsqueda sistemática usando las palabras clave: melanoma primario y vagina en las bases de datos Medline vía PubMed, Cochrane y Ebsco. Resultados: se encontraron 489 artículos de los cuales 31 estaban relacionados directamente con el tema, de estos se seleccionaron diez que correspondieron a nueve reportes de caso y a una revisión del tema. El diagnóstico clínico no es fácil. Las proteínas HMB45 y S100 son de gran utilidad en su identificación. La respuesta al tratamiento quirúrgico, la radioterapia y la quimioterapia es pobre. El pronóstico depende de la ploidía, la amelanosis y el índice mitótico. Conclusiones: el melanoma primario de vagina es una neoplasia rara y de mal pronóstico. Hace parte del grupo de melanomas de mucosa que tienen un origen y comportamiento biológico diferente al cutáneo. Tiene tendencia a la diseminación hematógena rápida y a recaídas locales. El tratamiento se basa en cirugía conservadora, radioterapia, quimioterapia y terapia biológica; sin embargo, su eficacia es limitada. Abstract in english Objective: reviewing clinical, histological and immunohistochemical diagnosis, therapeutic alternatives and factors influencing prognosis for amelanotic melanoma of the vagina. Materials and methods: this article presents the case of a 49yearold patient who consulted the Engativá Hospital’s Cervical [...] Pathology and Colposcopy Unit due to an 8 cm diameter necrotic pearlywhite vaginal mass on the anterior vaginal wall. The hospital is a secondary level complexity institution dealing with low socioeconomic level patients affiliated to the public (subsidized) social security (health) system. A broad resection was made of the lesion. Surgical pathology revealed epithelioid fusocellular malignant melanoma. A systematic literature search was made using the following key words: primary melanoma and vagina in Medline databases via Pub Med, Cochrane and Ebsco. Results: 31 of the 489 articles found were directly related to the topic; 10 new case reports and a review were selected. Clinical diagnosis is not easy; HMB45 and S100 proteins are extremely useful in identifying it.Response to surgical treatment, radiotherapy and chemotherapy is poor. Prognosis depends on ploidy, amelanosis and mitotic index. Conclusions: Primary melanoma of the vagina is a rare neoplasm and has a poor prognosis. It forms part of a group of mucosal melanoma having an origin and biological behavior different to that of cutaneous melanoma. It tends to have rapid hematogenous dissemination and local relapses. Treatment is based on conservative surgery, radiotherapy, chemotherapy and biological therapy; however, its effectiveness is limited.

  10. Morphology of the turkey vagina with and without an egg mass in the uterus.

    Science.gov (United States)

    Bakst, M R; Akuffo, V

    2009-03-01

    In this study we examined the gross anatomy of the uterus and vagina in turkeys in egg production. With no uterine egg mass, removal of the tunica serosa that enclosed the uterus revealed deep periodic in-folding of the muscularis transversely circumscribing the sac-like segment. When the connective tissue embracing the neutral buffered formalin fixed vagina was completely teased free, the exposed tubular segment was shaped as a counter-clockwise spiral or as a series of angular, random bends. The uterovaginal junction was flush with the uterine mucosa or projected slightly into the uterine lumen. With a uterine egg mass, the deep in-foldings of the uterus were abolished. The only alteration to the morphology of the vagina was that the uterovaginal junction appeared dilated and pressed into its juncture with the uterus. Whether an egg mass was present or not, uterovaginal junction folds that projected into the uterus possessed sperm storage tubules. An egg mass in the uterus compressed the uterovaginal junction folds, and its mucosa became contiguous with the uterine mucosa. Finally, from an evolutionary perspective, in the turkey and possibly other species possessing a nonintromittent phallus, vaginal pleomorphism may have been driven primarily by the need to accommodate the overall length of the vagina in a limited abdominal space and to a lesser extent on sexual selection. PMID:19211535

  11. Non-Diethylstilbestrol-Associated Primary Clear Cell Carcinoma of the Vagina: Two Case Reports with Immunohistochemical Studies and Literature Review

    Directory of Open Access Journals (Sweden)

    Shagufta T. Mufti

    2015-05-01

    Full Text Available Primary clear cell adenocarcinomas most commonly involve the genitourinary system, including the vagina. Previously, primary clear cell adenocarcinomas of the vagina have been discussed within the context of prenatal exposure to diethylstilbestrol. Due to its widely proven role in the development of this carcinoma, administration of diethylstilbestrol is prohibited. We present two cases of non-diethylstilbestrol-associated primary clear cell adenocarcinoma of the vagina from the archives of the Anatomical Pathology Department at King Abdulaziz University in order to improve our understanding of its biological behavior. Our findings suggest that primary clear cell adenocarcinoma of the vagina may be unrelated to diethylstilbestrol exposure and that non-diethylstilbestrol-associated primary clear cell adenocarcinoma of the vagina, when present at a younger age, may have a worse prognosis.

  12. Mioepitelioma de vagina: neoplasia poco frecuente en esta localización, reporte de un caso

    Scientific Electronic Library Online (English)

    Alfredo, Romero R; Mario, Melo U; Paula, Barajas S; Juvenal, Baena A; Luz Mery, Vargas L.

    Full Text Available Antecedentes: Los mioepiteliomas, son tumores poco frecuentes originados a partir de la proliferación de células mioepiteliales. La mayor parte localizados en las extremidades inferiores y en glándulas salivales. Existen ocasionales informes previos de MEP que involucren la vagina. Objetivo: Describ [...] ir un caso de mioepitelioma localizado en vagina. Caso clínico: Embarazada de 29 años edad, quien presenta una masa vaginal de un año de evolución, localizada en el himen. El examen histopatológico muestra una lesión compuesta por células fusiformes con positividad inmunohistoquímica para vimentina, citoqueratinas (CK) AE1/ AE3, S100, CD10, receptores de estrógenos y progesterona, Bcl2 y calponina y negatividad para desmina, actina muscular especifica, actina de músculo liso y p63. Con los anteriores hallazgos se interpreta la lesión como un mioepitelioma primario vaginal. Conclusión: Los mioepiteliomas son tumores que requieren para su diagnostico, análisis con técnicas de inmunohistoquímica o ultraestructurales que permitan diferenciarlos de otros tumores. Abstract in english Background: The myoepitheliomas are rare tumors arising from the proliferation of myoepithelial cells. Most tumors are located in the lower extremity and salivary glands. There have been only occasional myoepithelial neoplasms previously reported involving the vagina. Objective: Describe a case of m [...] yoepithelioma located in the vagina of a pregnant woman. Case report: A 29 years old pregnant female, who about 1 year prior has a vaginal mass, located in the hymen. At histopathological examination shows a mass composed of spindle cells with positivity immunohistochemical studies for vimentin, cytokeratin AE1/AE3, S100, CD10 and calponin and negative for desmin, actinmuscle specific (HHF35), smooth muscle actin and p63. With these findings it was established the diagnosis of myoepithelioma in the vagina. Conclusion: Myoepitheliomas are tumors requiring for diagnostic of immunohistochemistry or ultrastructural techniques that allow its differentiation from other tumors.

  13. Mioepitelioma de vagina: neoplasia poco frecuente en esta localización, reporte de un caso

    Directory of Open Access Journals (Sweden)

    Alfredo Romero R

    2012-01-01

    Full Text Available Antecedentes: Los mioepiteliomas, son tumores poco frecuentes originados a partir de la proliferación de células mioepiteliales. La mayor parte localizados en las extremidades inferiores y en glándulas salivales. Existen ocasionales informes previos de MEP que involucren la vagina. Objetivo: Describir un caso de mioepitelioma localizado en vagina. Caso clínico: Embarazada de 29 años edad, quien presenta una masa vaginal de un año de evolución, localizada en el himen. El examen histopatológico muestra una lesión compuesta por células fusiformes con positividad inmunohistoquímica para vimentina, citoqueratinas (CK AE1/ AE3, S100, CD10, receptores de estrógenos y progesterona, Bcl2 y calponina y negatividad para desmina, actina muscular especifica, actina de músculo liso y p63. Con los anteriores hallazgos se interpreta la lesión como un mioepitelioma primario vaginal. Conclusión: Los mioepiteliomas son tumores que requieren para su diagnostico, análisis con técnicas de inmunohistoquímica o ultraestructurales que permitan diferenciarlos de otros tumores.Background: The myoepitheliomas are rare tumors arising from the proliferation of myoepithelial cells. Most tumors are located in the lower extremity and salivary glands. There have been only occasional myoepithelial neoplasms previously reported involving the vagina. Objective: Describe a case of myoepithelioma located in the vagina of a pregnant woman. Case report: A 29 years old pregnant female, who about 1 year prior has a vaginal mass, located in the hymen. At histopathological examination shows a mass composed of spindle cells with positivity immunohistochemical studies for vimentin, cytokeratin AE1/AE3, S100, CD10 and calponin and negative for desmin, actinmuscle specific (HHF35, smooth muscle actin and p63. With these findings it was established the diagnosis of myoepithelioma in the vagina. Conclusion: Myoepitheliomas are tumors requiring for diagnostic of immunohistochemistry or ultrastructural techniques that allow its differentiation from other tumors.

  14. Morphological Studies on the Vagina and Vestibule of Dromedary Camels (Camelus dromedarius) / Estudios Morfológicos de la Vagina y Vestíbulo del Camello (Camelus dromedarius)

    Scientific Electronic Library Online (English)

    Ahmed, Sayed-Ahmed; Anwer, Elshafey; Ahmed, Abd-Elmaksoud.

    2014-12-01

    Full Text Available El camello (Camelus dromedarius) es una importante especie de ganado de usos múltiples y el consumo de su carne corresponde al 10% aproximadamente del consumo de carne roja en Egipto. La eficiencia reproductiva del camello, bajo condiciones naturales, se considera generalmente baja. El conocimiento [...] adecuado sobre los órganos genitales tubulares de esta especie podría facilitar la aplicación de una nueva metodología de reproducción. Por lo tanto, se llevó a cabo este estudio para investigar la morfología de la superficie de la mucosa de la vagina y el vestíbulo en camellos, utilizando luz, escaneado y microscopía electrónica de transmisión. La superficie de la mucosa de la vagina está formado por epitelio columnar estratificado con células secretoras mucosas (células en copa). La microscopía electrónica de barrido (SEM) de la vagina reveló la presencia de pliegues primarios y secundarios longitudinales y pequeños pliegues transversales. El epitelio columnar mostró un límite celular marcado y su superficie apical se evidenció salpicado por una gran cantidad de microvellosidades. La microscopía electrónica por transmisión (TEM) confirmó la presencia de microvellosidades en las superficies apicales y mostró algunos gránulos secretores en la región supranuclear del epitelio columnar. El vestíbulo del dromedario está revestido por epitelio estratificado queratinizado, de tipo escamoso. La lámina basal y el estrato granuloso de este epitelio mostraron una fuerte reacción PAS positiva. La microscopía electrónica de barrido (SEM) del vestíbulo reveló la presencia de pequeños pliegues transversales longitudinales y finos, con gran cantidad de restos de mucosidad. Sin embargo, la microscopía electrónica por transmisión (TEM) del vestíbuloreveló un epitelio queratinizado escamoso estratificado, con una capa basal de células cúbicas y capas superficiales de células escamosas. Abstract in english The camel (Camelus dromedarius) is an important multipurpose livestock species and its meat represents about 10% of the red meat consumption in Egypt. The reproductive efficiency of camel under natural condition is generally considered to be low. Sound knowledge about the tubular genital organs of t [...] his species might facilitate the application of new reproductive methodology. Our study was therefore conducted to investigate the morphology of mucosal surface of vagina and vestibule on camels using light, scanning and transmission electron microscopy. The mucosal surface of vagina consisted of stratified columnar epithelium with mucous secreting cells (goblet-like cells). SEM of vagina revealed the presence of longitudinal primary and secondary folds and small transverse folds. The columnar epithelium showed marked cell boundary and its apical surface was studded by a lot of microvilli. TEM confirmed the presence of microvilli at apical surfaces and showed some secretory granules in the supranuclear region of the columnar epithelium. The vestibule of dromedary camel was lined by stratified squamous keratinized epithelium. Basal lamina and stratum granulosum of this epithelium showed strong PAS positive reaction. SEM of vestibule revealed the presence of small longitudinal and fine transverse folds with a lot of mucous debris. However TEM of vestibule showed the stratified squamous keratinized epithelium with basal layer of cuboidal cells and superficial layers of squamous cells.

  15. Sex Hormones Coordinate Neutrophil Immunity in the Vagina by Controlling Chemokine Gradients.

    Science.gov (United States)

    Lasarte, Sandra; Samaniego, Rafael; Salinas-Muñoz, Laura; Guia-Gonzalez, Mauriel A; Weiss, Linnea A; Mercader, Enrique; Ceballos-García, Elena; Navarro-González, Teresa; Moreno-Ochoa, Laura; Perez-Millan, Federico; Pion, Marjorie; Sanchez-Mateos, Paloma; Hidalgo, Andres; Muñoz-Fernandez, Maria A; Relloso, Miguel

    2016-02-01

    Estradiol-based contraceptives and hormonal replacement therapy predispose women to Candida albicans infections. Moreover, during the ovulatory phase (high estradiol), neutrophil numbers decrease in the vaginal lumen and increase during the luteal phase (high progesterone). Vaginal secretions contain chemokines that drive neutrophil migration into the lumen. However, their expression during the ovarian cycle or in response to hormonal treatments are controversial and their role in vaginal defense remains unknown.To investigate the transepithelial migration of neutrophils, we used adoptive transfer of Cxcr2(-/-) neutrophils and chemokine immunofluorescence quantitative analysis in response to C. albicans vaginal infection in the presence of hormones.Our data show that the Cxcl1/Cxcr2 axis drives neutrophil transepithelial migration into the vagina. Progesterone promotes the Cxcl1 gradient to favor neutrophil migration. Estradiol disrupts the Cxcl1 gradient and favors neutrophil arrest in the vaginal stroma; as a result, the vagina becomes more vulnerable to pathogens. PMID:26238687

  16. Long-term results of radiotherapy in primary carcinoma of the vagina

    Energy Technology Data Exchange (ETDEWEB)

    Hegemann, Stefan; Willich, Normann [University Hospital, Muenster (Germany). Dept. of Radiotherapy and Radiation Oncology; Schaefer, Ulrich [University Hospital, Muenster (Germany). Dept. of Radiotherapy and Radiation Oncology; Lippe Hospital, Lemgo (Germany). Dept. of Radiotherapy; Lelle, Ralph [University Hospital, Muenster (Germany). Dept. of Gynecology and Gynecologic Oncology; Micke, Oliver [University Hospital, Muenster (Germany). Dept. of Radiotherapy and Radiation Oncology; Franziskus Hospital, Bielefeld (Germany). Dept. of Radiotherapy and Radiation Oncology

    2009-03-15

    Background: The long-term results of radiotherapy in primary carcinoma of the vagina are not well defined. Patients and Methods: The treatment results of 41 patients with primary malignancies of the vagina were analyzed. The mean follow-up period was 77.3 months (2.3-404 months). The predominant histology was squamous cell carcinoma, FIGO stages I: n = 7 (17.1%), II: n = 13 (31.7%), III: n = 13 (31.7%), and IVa: n = 8 (19.5%). Radiotherapy was the primary treatment for all patients. None of the patients had undergone prior surgery for vaginal carcinoma. The majority of patients received pelvic irradiation, including treatment of the inguinal lymphatics (median dose: 50 Gy). 26 patients received additional intravaginal brachytherapy. Results: Overall, 21 patients (51.2%) achieved complete remission, 17 patients (41.5%) had partial responses, and three patients (7.3%) had no change or progressive disease. The total median survival of the analyzed patients was 41.3 months. The 1-year survival probability was 85.4%, the 5-year survival probability 40.6%, and the 10-year survival probability 27.2%. Univariate analysis revealed a survival advantage for earlier tumor stages (FIGO I and II) compared to advanced stages (FIGO III and IV), with a median survival of 58.1 months compared to 26.8 months. Treatment side effects were tolerable and easily managed. Conclusion: Definite radiotherapy is the treatment of choice for primary carcinomas of the vagina. Considering that primary malignancies of the vagina are typically diseases of the elderly, it should be noted that radiotherapy is especially well tolerated in this population. (orig.)

  17. Brachytherapy for malignancies of the vagina in the 3D era

    OpenAIRE

    Glaser, Scott M.; Beriwal, Sushil

    2015-01-01

    Vaginal cancer is an uncommon malignancy and can be either recurrent or primary. In both cases, brachytherapy places a central role in the overall treatment course. Recent technological advances have led to more advanced brachytherapy techniques, which in turn have translated to improved outcomes for patients with malignancies of the vagina. The aim of this manuscript is to outline the incorporation of modern brachytherapy into the treatment of patients with vaginal cancer including patient s...

  18. Entrenamiento de carneros para recolección de semen mediante vagina artificial, utilizando como estímulo objetos inanimados

    OpenAIRE

    Virginio Aguirre Flores; Reyes V\\u00E1zquez Rosales; Agust\\u00EDn Orihuela Trujillo

    2005-01-01

    Con el fi n de desarrollar una metodología para entrenar carneros en la recolección de semen con vagina artifi cial (VA), montando un objeto inanimado, se utilizaron nueve animales que se sometieron a cuatro etapas de preparación. La primera con el propósito de lograr la manifestación del repertorio sexual natural, y el resto para llevar a cabo un programa de condicionamiento operante: cuando la respuesta correcta (monta) sucedía, en un inicio provocada por un estado de motivac...

  19. CT and MR imaging findings of primary leiomyosarcoma of the vagina : a case report

    Energy Technology Data Exchange (ETDEWEB)

    Cho, So Hee; Rha, Sung Eun; Cho, Song Mee; Byun, Jae Young [College of Medicine, The Catholic Univ. of Korea, Seoul (Korea, Republic of)

    2001-09-01

    Primary malignant lesions of the vagina are uncommon and represent approximately 1-2% of all gynecologic malignancies. About 2% of all malignant vaginal lesions are primary sarcomas, the most common of these being leiomyosarcoma. We report the CT and MR imaging findings in a 41-year-old woman with vaginal leiomyosarcoma presenting as a bulky solid mass which caused expansion of the vaginal canal.

  20. Hematocolpos in double vagina associated with uterus didelphus: US and MR findings

    Energy Technology Data Exchange (ETDEWEB)

    Ballesio, L.; Andreoli, C.; De Cicco, M.L.; Angeli, M.L.; Manganaro, L

    2003-02-01

    The malformative syndrome of double vagina in association with uterus didelphus and kidney agenesis is a rare condition, often asymptomatic: if this condition is accompanied by imperforated obstructed hemivagina, the clinical manifestations depend on the presence of hematocolpos. MRI plays an important role for diagnosis because it allows to characterize the nature of the lesion and to evaluate the anatomical details of the uterine malformation. The authors describe this complex genital malformation and discuss the main US and MRI features.

  1. Verrucous carcinoma of the cervix and vagina treated by radiation therapy

    International Nuclear Information System (INIS)

    Seven cases of verrocous carcinoma of the uterine cervix (five) and vagina (two) were reviewed. Four of the five patients managed primarily with radiation therapy have survived a median of 10 years. Of the two patients managed primarily with surgery, one experienced recurrence and was then successfully treated with radiation therapy; the other died of metastatic carcinoma. No anaplastic transformation of lesions or distant metastases occurred in the patients treated with radiation therapy. Human papilloma virus was isolated in two patients

  2. The oophorectomy effect on Walker 256 tumor inoculated into the vagina and uterine cervix of female rats Efeito da ooforectomia no tumor de Walker 256 inoculado em vagina e colo de útero de ratos fêmeas

    OpenAIRE

    Nara Macedo Botelho Brito; Rita de Kássia Vidigal Carvalho; Lia Tavares de Moura Brasil Matos; Rodolfo Costa Lobato; Rosângela Baía Brito

    2009-01-01

    PURPOSE: Verify the effect of oophorectomy on the evolution of the Walker 256 tumor inoculated into the vagina and cervix of female rats. METHODS: Ten Wistar, female rats were used, distributed into two groups with 05 animals each: Tumor group (TG): Rats inoculated with Walker 256 tumor; Oophorectomy group (OG): oophorectomized rats inoculated with Walker 256 tumor. The day before the tumor vaginal inoculation, acetic acid was inoculated into the vaginas of both groups of rats; the following ...

  3. A case of primary mucosa-associated lymphoid tissue lymphoma of the vagina.

    Science.gov (United States)

    Yoshinaga, Kousuke; Akahira, Jun-Ichi; Niikura, Hitoshi; Ito, Kiyoshi; Moriya, Takuya; Murakami, Takashi; Kameoka, Jun-Ichi; Ichinohasama, Ryo; Okamura, Kunihiro; Yaegashi, Nobuo

    2004-09-01

    We report the first case of primary mucosa-associated lymphoid tissue (MALT) lymphoma of the vagina, the diagnosis of which is supported by genetic and immunophenotypic studies. A 65-year-old, para 2 woman presented to our hospital in July 1997 with a history of prolonged vaginal discharge. Although cytologic examination suggested possible malignancy, a biopsy of the vaginal wall was diagnosed as chronic inflammation. In June 2000, she underwent gynecologic examination because of anuria. Excisional biopsy revealed subepithelial infiltration of atypical lymphoid cells that stained for CD20, CD79a, and BCL-2; stained weakly for IgM; and did not stain for CD3, CD5, CD7, CD10, CD56, CD23, and IgD, suggesting marginal zone B-cell lineage. Monoclonality was detected by Southern blot analysis, and this patient was finally diagnosed as having primary MALT lymphoma of the vagina. She received 3 cycles of chemotherapy (THP-COP) and concurrent radiation to the whole pelvis. The patient is alive and well 40 months after treatment. Because the vagina is one of the mucosa-associated tissues, MALT lymphoma, though rare, must be included in the differential diagnosis of the vaginal neoplasms. PMID:15343521

  4. Compensatory structural adaptive modifications of vagina in response to functional demand in goat.

    Science.gov (United States)

    Hussin, Amer M; Zaid, Nazih W; Hussain, S O

    2014-01-01

    Vaginal biopsies and smears were collected from ten adult local healthy goats. Routine histological methods were carried out on vaginal biopsies and then stained with PAS stain. The smears were stained with Methylene blue. All samples were inspected under light microscope. The present study found that many constituents of the wall of the vagina, which have an important functional role, were absent; among these were the vaginal glands, goblet cells, muscularis mucosa, and lymphatic nodules. On the other hand, vagina showed special compensatory histological mechanisms, namely, the deep epithelial folds, the well-developed germinated stratum basale, the apparent basement membrane, and the profuse defensive cells, such as neutrophils, macrophages, lymphocytes, plasma cells, and mast cells. The general stains of this study could not recognize dendritic cells although they play an important functional role. Moreover, the herein study declared also that the vaginal smears showing many adaptive cellular mechanisms among these were, the keratinization, the process of sheet formation that lines the vaginal lumen, the process of metachromasia which is related to the cellular activity in protein synthesis, keratin, and finally the presence of endogenous microorganisms. It was concluded that all the above cellular compensatory adaptive mechanisms may compensate the lacking vaginal constituents and act to raise the immune response of the vagina. PMID:24707438

  5. Placement of temperature probe in bovine vagina for continuous measurement of core-body temperature

    Science.gov (United States)

    Lee, C. N.; Gebremedhin, K. G.; Parkhurst, A.; Hillman, P. E.

    2015-09-01

    There has been increasing interest to measure core-body temperature in cattle using internal probes. This study examined the placement of HOBO water temperature probe with an anchor, referred to as the "sensor pack" (Hillman et al. Appl Eng Agric ASAE 25(2):291-296, 2009) in the vagina of multiparous Holstein cows under grazing conditions. Two types of anchors were used: (a) long "fingers" (4.5-6 cm), and (b) short "fingers" (3.5 cm). The long-finger anchors stayed in one position while the short-finger anchors were not stable in one position (rotate) within the vagina canal and in some cases came out. Vaginal temperatures were recorded every minute and the data collected were then analyzed using exponential mixed model regression for non-linear data. The results showed that the core-body temperatures for the short-finger anchors were lower than the long-finger anchors. This implied that the placement of the temperature sensor within the vagina cavity may affect the data collected.

  6. First record of the burrowing goby, Trypauchen vagina (Actinopterygii: Gobiidae), from the Iranian coast of the Persian Gulf

    OpenAIRE

    YEGANEH, MOHAMMAD SADEGH ALAVI; DEYRESTANI, ABDOLLAH; MURDY, EDWARD O.

    2015-01-01

    The burrowing goby, Trypauchen vagina, is recorded for the first time from the Iranian coast of the Persian Gulf. Only one other record is known for this species from the Persian Gulf; that record is from Kuwait. The subject record is a new addition to the ichthyofauna of Iran resulting from four T. Vagina specimens being collected from north of Qeshm Island in the Khoran Strait (26°56?N, 55°54?E) in the Persian Gulf.

  7. Association of Atopobium vaginae, a recently described metronidazole resistant anaerobe, with bacterial vaginosis

    Directory of Open Access Journals (Sweden)

    Fortenberry J Dennis

    2004-02-01

    Full Text Available Abstract Background Bacterial vaginosis (BV is a polymicrobial syndrome characterized by a change in vaginal flora away from predominantly Lactobacillus species. The cause of BV is unknown, but the condition has been implicated in diverse medical outcomes. The bacterium Atopobium vaginae has been recognized only recently. It is not readily identified by commercial diagnostic kits. Its clinical significance is unknown but it has recently been isolated from a tuboovarian abcess. Methods Nucleotide sequencing of PCR amplified 16S rRNA gene segments, that were separated into bands within lanes on polyacrylamide gels by denaturing gradient gel electrophoresis (DGGE, was used to examine bacterial vaginal flora in 46 patients clinically described as having normal (Lactobacillus spp. predominant; Nugent score ? 3 and abnormal flora (Nugent score ? 4. These women ranged in age from 14 to 48 and 82% were African American. Results The DGGE banding patterns of normal and BV-positive patients were recognizably distinct. Those of normal patients contained 1 to 4 bands that were focused in the centre region of the gel lane, while those of BV positive patients contained bands that were not all focused in the center region of the gel lane. More detailed analysis of patterns revealed that bands identified as Atopobium vaginae were present in a majority (12/22 of BV positive patients, while corresponding bands were rare (2/24 in normal patients. (P A. vaginae isolates were cultivated from two patients whose DGGE analyses indicated the presence of this organism. Two A. vaginae 16S rRNA gene sequences were identified among the clinical isolates. The same two sequences were obtained from DGGE bands of the corresponding vaginal flora. The sequences differed by one nucleotide over the short (~300 bp segment used for DGGE analysis and migrated to slightly different points in denaturing gradient gels. Both isolates were strict anaerobes and highly metronidazole resistant. Conclusion The results suggest that A. vaginae may be an important component of the complex bacterial ecology that constitutes abnormal vaginal flora. This organism could play a role in treatment failure if further studies confirm it is consistently metronidozole resistant.

  8. Melanosis of the vagina and human papillomavirus infection, an uncommon pathology: Case Report / Melanosis de la vagina e infección por virus del papiloma humano, una patología poco común: Reporte de un Caso

    Scientific Electronic Library Online (English)

    José, Núñez-Troconis; Mariela, Delgado; Gerardo, González; Airiaudis, Rivas; Katherine, Molero.

    2011-09-01

    Full Text Available Las lesiones melanóticas de la vagina son infrecuentes. y Solo pocos casos han sido reportados. Se presenta el caso de una mujer de 34 años quien es referida con diagnóstico de una Neoplasia Intraepitelial Vaginal 1. Al examen ginecológico, se encontraron dos áreas hiperpigmentadas en la vagina. La [...] exploración colposcópica del cuello uterino y vagina reveló la presencia de una lesión aceto-blanca en la pared lateral derecha del tercio superior de la vagina. Muestras de biopsias fueron tomadas en dichas áreas. El estudio histológico reportó una melanosis de la vagina y una infección por el virus del Papiloma Humano (VPH). Se realizó un panel de estudio inmunohistoquímico de marcadores epiteliales en las muestras vaginales: tales como citoqueratina AE1/AE3 y antígeno epitelial de membrana; marcador mesenquimal: vimentin; marcadores melanóticos: proteina S-100 y HMB45 (Human Melanoma Black); marcadores de proliferación celular: antígeno de proliferación nuclear (PCNA), y la oncoproteína P-53. Se realizó Hibridización In Situ para establecer los tipos de alto (16, 18, 31, 45) y bajo (6, 11) riesgo de VPH en las muestras vaginales. Los marcadores CK, EMA y Vimentin fueron 2+. Los marcadores melanótico, el HMB45 y el S100, y el PCNA fueron 1+ en la capa basal. P-53 fue negativo. El tejido melanótico y la lesión acetoblanca fueron positivos al VPH 6,11. En conclusión, la melanosis vaginal es una patología poco frecuente. Usualmente, se ha reportado en mujeres mayores de 40 años. Presentamos un caso de una melanosis de la vagina infectada con un tipo de VPH de bajo riesgo en una mujer joven y una revisión de la literatura. Abstract in english Benign melanotic lesions of the vagina are uncommon and only a few cases have been reported in the literature. A 34-year-old woman was referred because of a Vaginal Intraepithelial Neoplasia 1 biopsy result. On the gynecological examination, two different hyperpigmented areas were noted in the vagin [...] a. The colposcopic visualization of the cervix and vagina found an aceto-white lesion at the right lateral wall of the upper third of the vagina. Biopsies from three areas were taken. Histological study reported a melanosis of the vagina and HPV infection. An immunohistochemical panel of epithelial markers was performed in vaginal samples, such as Cytokeratin AE1/AE3 and epithelial membrane antigen, mesenchymal marker: vimentin; melanocytic makers: protein S-100 and HMB45 (Human Melanoma Black); proliferating cell marker: proliferating cell nuclear antigen (PCNA), and P-53 oncoprotein. High Risk (16, 18, 31, 45) and Low Risk (6, 11) HPV types were studied by In Situ Hybridization using the same vaginal samples. CK, EMA and Vimentin were 2+. Melanocytic markers, HMB45 and S100, and PCNA were 1+ in basal cell layer. P-53 was negative. The melanotic tissue and acetowhite lesion were positives to HPV Types 6,11. In conclusion, melanosis of the vagina is a uncommon benign pathology. Usually, melanosis is present in women over 40 years old. We present a case of melanosis of the vagina in a young woman infected with low-risk HPV types and review the literature.

  9. Antibiogram of Group B Streptococci Isolated from the Vagina of Pregnant

    Directory of Open Access Journals (Sweden)

    Vinay Hajare, *L.H. Madhavi, **H.K.G. Singh

    2012-01-01

    Full Text Available Group B streptococcal (GBS prevalence varies from place to place; this organism is responsible for serious infections in newborns, such as septicemia and meningitis. The present study was aimed to find out the antibiogram of Group B Streptococci isolated from the vagina of pregnant women who were in the third trimester of pregnancy and toidentify the risk factors for its colonization in vagina. The study was carried out in the Department of Microbiology, M. R. Medical College & Hospital, Gulbarga during a period from January 2007 to December 2007. Two hundred pregnant women who were in the third trimester of pregnancy and attending the antenatal clinics were included in the study. Two low vaginal swabs were taken from each women included in the study and were immediately transported to the laboratory for processing. Direct gram staining was done from one swab and the other swab was inoculated into sheep blood agar plate and incubated at 37ºC for 24-48 hours. Identification of organism was based on gram staining, colony morphology, catalase reaction,Christie Atkins Munch Petersen (CAMP and Hippurate hydrolysis test.Of the 200 pregnant women screened, 7.5% were colonized by GBS. Incidence of GBS colonization was higher among pregnant women in the third trimester who were 25 years of age and primigravida. All the isolates were sensitive to Ampicillin, Erythromycin and Penicillin but were resistant to Gentamicin and Kanamycin.

  10. Microbiologic characteristics of Lactobacillus products used for colonization of the vagina.

    Science.gov (United States)

    Hughes, V L; Hillier, S L

    1990-02-01

    Lactobacilli have long been considered to be the protective flora in the vagina. Women with vaginal infections have used various non-prescription products in an attempt to restore their normal vaginal flora. Products that contain lactobacilli include dairy products (yogurt, acidophilus milk) and commercially available Lactobacillus powders and tablets. Recently, Lactobacillus species that produce hydrogen peroxide (H2O2) have been associated with normal vaginal flora. In this study, we compared 16 non-prescription products containing lactobacilli for H2O2 production, purity, and identifiable contaminants. All 16 products contained lactobacilli, of which ten (62%) produced H2O2. At least one contaminant was detected in 11 of 16 (69%) of the products: Enterococcus faecium (ten), Clostridium sporogenes (one), Streptococcus mitis (one), and Pseudomonas species (one). Although all of the products tested contained lactobacilli, only four of the products contained Lactobacillus acidophilus. Most of the lactobacilli-containing products currently available either do not contain the Lactobacillus species advertised and/or contain other bacteria of questionable benefit. We conclude that commercially available products may not be appropriate for recolonization of the vagina. PMID:2300352

  11. Epithelial estrogen receptor 1 intrinsically mediates squamous differentiation in the mouse vagina.

    Science.gov (United States)

    Miyagawa, Shinichi; Iguchi, Taisen

    2015-10-20

    Estrogen-mediated actions in female reproductive organs are tightly regulated, mainly through estrogen receptor 1 (ESR1). The mouse vaginal epithelium cyclically exhibits cell proliferation and differentiation in response to estrogen and provides a unique model for analyzing the homeostasis of stratified squamous epithelia. To address the role of ESR1-mediated tissue events during homeostasis, we analyzed mice with a vaginal epithelium-specific knockout of Esr1 driven by keratin 5-Cre (K5-Esr1KO). We show here that loss of epithelial ESR1 in the vagina resulted in aberrant epithelial cell proliferation in the suprabasal cell layers and led to failure of keratinized differentiation. Gene expression analysis showed that several known estrogen target genes, including erbB growth factor ligands, were not induced by estrogen in the K5-Esr1KO mouse vagina. Organ culture experiments revealed that the addition of erbB growth factor ligands, such as amphiregulin, could activate keratinized differentiation in the absence of epithelial ESR1. Thus, epithelial ESR1 integrates estrogen and growth factor signaling to mediate regulation of cell proliferation in squamous differentiation, and our results provide new insights into estrogen-mediated homeostasis in female reproductive organs. PMID:26438838

  12. A longitudinal study of Staphylococcus hyicus colonization of vagina of gilts and transmission to piglets

    DEFF Research Database (Denmark)

    Wegener, Henrik Caspar; Skov Jensen, E.W.

    1992-01-01

    High Staphylococcus hyicus colonization rates were found in vaginal samples of healthy breeding sows and in skin samples of their offspring. Twenty-two different phage types were identified among the 720 isolates of S. hyicus examined. Two to 13 different phage types were isolated per herd. Phage typing, as well as characterization of about 10 % of the isolates by plasmid profiles and antibiogram patterns, showed that, several different clones of S. hyicus could be present simultaneously in vagina of gilts and also on skin of piglets. Generally isolates from the vagina of one animal were identical as regards to phage types, plasmid profiles, and antibiogram patterns during the entire investigation period. Isolates from the skin of piglets were of the same type as their mothers, indicating that vertical transmission had taken place. S. hyicus strains isolated from the skin of piglets within 24 h after birth were identical to strains isolated 3 weeks after birth from the same litter, indicating that the vaginalstrains became part of a stable skin flora.

  13. Migration of a particulate radioactive tracer from the vagina to the peritoneal cavity and ovaries

    International Nuclear Information System (INIS)

    In this report we describe a radionuclide procedure designed to evaluate the migration of a particulate radioactive tracer from the vagina to the peritoneal cavity and ovaries, as well as the determination of the patency of the pathways between these two extremes of the female reproductive system. Technetium-99m-labelled human albumin microspheres (technetium-99m-HAM) were deposited in the posterior fornices of 24 patients a day before they were to undergo different gynaecological operations. During this period sequential images were obtained and after the operation radioactivity levels in the removed organs and tissues were counted with a scintillation detector. In 14 out of 21 cases, the ovaries and fallopian tubes were counted separately from the uterus. Nine were positive (radioactivity levels were sufficiently high in the tubes and ovaries) and 5 were negative (no substantial radioactivity levels could be detected in either the tubes or the ovaries). The 5 negative results all occurred in patients with proved tubal damage as a result of previous infection. All the results were either true positive or true negative, providing evidence of migration, or obstruction, of technetium-99m-HAM from the vagina through the uterus and tubes to the peritoneal cavity and ovaries

  14. Radicality of initial surgery for primary malignant melanoma of the vagina.

    Science.gov (United States)

    Todo, Yukiharu; Okamoto, Kazuhira; Suzuki, Yoshihiro; Minobe, Shinichiro; Kato, Hidenori

    2016-04-01

    Radical surgery is considered not to improve the prognosis of primary malignant melanoma of the vagina (PMMV). This study was carried out to review the general consensus. A systematic review was performed on the basis of data from 10 patients in our cohort and 147 patients in the previous literature. The radicality of the initial surgery (RAINS) score was defined as the total number of points in terms of the resected organs. The target organs were the vagina, vulva, urethra, bladder, uterus, anus, rectum, pelvic lymph nodes, and inguinal lymph nodes. Overall survival (OS) according to the RAINS score was analyzed using the Kaplan-Meier method. Information on tumor stage, size, and depth of invasion was not obtained in 15, 47, and 43% of patients, respectively. The median follow-up period was 18 months. OS with a RAINS score of at least 7 was significantly longer than that with a RAINS score of up to 6 (median survival time, 41 vs. 19 months; log-rank test, P=0.037), despite the fact that the former group included significantly more patients with advanced-stage disease. A significant difference in OS was not found between patients with a RAINS score of at least 6 and up to 5. The therapeutic significance of radical surgery for PMMV has not been assessed appropriately in previous studies because of the lack of comparability among groups and differences in the definitions of surgical radicality. Patients with PMMV might benefit from initial surgery with appropriate surgical radicality, despite incomplete validation of the RAINS score. PMID:26825038

  15. The oophorectomy effect on Walker 256 tumor inoculated into the vagina and uterine cervix of female rats / Efeito da ooforectomia no tumor de Walker 256 inoculado em vagina e colo de útero de ratos fêmeas

    Scientific Electronic Library Online (English)

    Nara Macedo Botelho, Brito; Rita de Kássia Vidigal, Carvalho; Lia Tavares de Moura Brasil, Matos; Rodolfo Costa, Lobato; Rosângela Baía, Brito.

    2009-02-01

    Full Text Available OBJETIVO: Verificar o efeito da ooforectomia à inoculação do tumor de Walker 256 em vagina e colo de útero de ratas. MÉTODOS: Foram utilizadas 10 ratas Wistar, fêmeas, virgens, adultas, distribuídas em dois grupos de estudo com 05 animais cada: grupo tumor (GT): ratas inoculadas com tumor de Walker [...] 256, e grupo Ooforectomia (GO): ratas ooforectomizadas e inoculadas com tumor de Walker 256. No dia anterior à inoculação vaginal do tumor, foram inoculados 0,3ml de ácido acético na vagina das ratas de ambos os grupos; no dia seguinte, foi realizada a escarificação da parede vaginal com uma escova de endocérvice e inoculado tumor de Walker 256. Após 12 dias, foi removido o tumor em bloco com vagina e cornos uterinos para análise macro e microscópica. Os dados foram submetidos à análise estatística. RESULTADOS: Não houve diferença estatística entre os dois grupos; no entanto, notou-se que o comportamento de crescimento do tumor no grupo GO apresentou maior invasividade em extensão, comprometendo cornos uterinos. CONCLUSÃO: Observou-se que o grupo GO apresentou comportamento macroscópico diferente ao grupo GT, no entanto, em termos totais de massa tumoral ambos apresentam desenvolvimento similar. Abstract in english PURPOSE: Verify the effect of oophorectomy on the evolution of the Walker 256 tumor inoculated into the vagina and cervix of female rats. METHODS: Ten Wistar, female rats were used, distributed into two groups with 05 animals each: Tumor group (TG): Rats inoculated with Walker 256 tumor; Oophorectom [...] y group (OG): oophorectomized rats inoculated with Walker 256 tumor. The day before the tumor vaginal inoculation, acetic acid was inoculated into the vaginas of both groups of rats; the following day, the vaginal walls were scarified with an endocervix brush, and then Walker 256 tumor was inoculated. After 12 days, the tumor was removed together with the vagina and uterine horns for macro and microscopic analyses. The data were submitted to statistical analyses. RESULTS: There was no statistical difference between the two groups; however it was observed that the behavior of tumor growth on the OG group presented greater invasion, compromising the uterine horns. CONCLUSION: The results of the study on the GO group presented a macroscopic behavior different from the TG group, however, both of them presented similar development in terms of tumor mass.

  16. The oophorectomy effect on Walker 256 tumor inoculated into the vagina and uterine cervix of female rats Efeito da ooforectomia no tumor de Walker 256 inoculado em vagina e colo de útero de ratos fêmeas

    Directory of Open Access Journals (Sweden)

    Nara Macedo Botelho Brito

    2009-02-01

    Full Text Available PURPOSE: Verify the effect of oophorectomy on the evolution of the Walker 256 tumor inoculated into the vagina and cervix of female rats. METHODS: Ten Wistar, female rats were used, distributed into two groups with 05 animals each: Tumor group (TG: Rats inoculated with Walker 256 tumor; Oophorectomy group (OG: oophorectomized rats inoculated with Walker 256 tumor. The day before the tumor vaginal inoculation, acetic acid was inoculated into the vaginas of both groups of rats; the following day, the vaginal walls were scarified with an endocervix brush, and then Walker 256 tumor was inoculated. After 12 days, the tumor was removed together with the vagina and uterine horns for macro and microscopic analyses. The data were submitted to statistical analyses. RESULTS: There was no statistical difference between the two groups; however it was observed that the behavior of tumor growth on the OG group presented greater invasion, compromising the uterine horns. CONCLUSION: The results of the study on the GO group presented a macroscopic behavior different from the TG group, however, both of them presented similar development in terms of tumor mass.OBJETIVO: Verificar o efeito da ooforectomia à inoculação do tumor de Walker 256 em vagina e colo de útero de ratas. MÉTODOS: Foram utilizadas 10 ratas Wistar, fêmeas, virgens, adultas, distribuídas em dois grupos de estudo com 05 animais cada: grupo tumor (GT: ratas inoculadas com tumor de Walker 256, e grupo Ooforectomia (GO: ratas ooforectomizadas e inoculadas com tumor de Walker 256. No dia anterior à inoculação vaginal do tumor, foram inoculados 0,3ml de ácido acético na vagina das ratas de ambos os grupos; no dia seguinte, foi realizada a escarificação da parede vaginal com uma escova de endocérvice e inoculado tumor de Walker 256. Após 12 dias, foi removido o tumor em bloco com vagina e cornos uterinos para análise macro e microscópica. Os dados foram submetidos à análise estatística. RESULTADOS: Não houve diferença estatística entre os dois grupos; no entanto, notou-se que o comportamento de crescimento do tumor no grupo GO apresentou maior invasividade em extensão, comprometendo cornos uterinos. CONCLUSÃO: Observou-se que o grupo GO apresentou comportamento macroscópico diferente ao grupo GT, no entanto, em termos totais de massa tumoral ambos apresentam desenvolvimento similar.

  17. La vagina dentada: una interpretación de la Estela 25 de Izapa y las guacamayas del juego de pelota de Copán The dented vagina: an interpretation for Stela 25 of Izapa and ballcourt macaws of Copan

    Directory of Open Access Journals (Sweden)

    Oswaldo Chinchilla Mazariegos

    2010-01-01

    Full Text Available Las aves representadas en la Estela 25 de Izapa y el juego de pelota de Copán forman el punto de partida para un examen del tema mitológico de la vagina dentada en Mesoamérica, y sus expresiones en el arte y la narrativa. Un amplio conjunto de narraciones mitológicas recopiladas en México y Guatemala sirve como base para un examen de la historia de Siete Guacamayo en el Popol Vuh, la cual se interpreta como una variante de un mito ampliamente difundido, relacionado con el origen del Sol y la Luna. La identificación de asuntos comunes, entre ellos el de la vagina dentada, refuerza la relación entre el mito del Popol Vuh y las representaciones de Izapa y Copán. A la vez, revela detalles poco conocidos sobre el simbolismo sexual presente en los mitos cosmogónicos mesoamericanos.The birds represented at Stela 25 of Izapa and Copan ball court are the starting point for the analysis of the mythological topic focused on the vagina dentata in Ancient Mesoamerica, as well as their expressions on art and narrative. A large body of mythological narratives is used as a basis for the examination of the "Siete Guacamayo" story included in the Popol Vuh, which is interpreted as part of a widely extended myth related with the creation of the Sun and the Moon. The identification of common issues, as the vagina dentata topic, strengthens the links between the Popol Vuh myth and the Izapa and Copan representations. It also reveals less known details on the sexual symbolism included in the Mesoamerican cosmogonic myths.

  18. La vagina dentada: una interpretación de la Estela 25 de Izapa y las guacamayas del juego de pelota de Copán / The dented vagina: an interpretation for Stela 25 of Izapa and ballcourt macaws of Copan

    Scientific Electronic Library Online (English)

    Oswaldo, Chinchilla Mazariegos.

    Full Text Available Las aves representadas en la Estela 25 de Izapa y el juego de pelota de Copán forman el punto de partida para un examen del tema mitológico de la vagina dentada en Mesoamérica, y sus expresiones en el arte y la narrativa. Un amplio conjunto de narraciones mitológicas recopiladas en México y Guatemal [...] a sirve como base para un examen de la historia de Siete Guacamayo en el Popol Vuh, la cual se interpreta como una variante de un mito ampliamente difundido, relacionado con el origen del Sol y la Luna. La identificación de asuntos comunes, entre ellos el de la vagina dentada, refuerza la relación entre el mito del Popol Vuh y las representaciones de Izapa y Copán. A la vez, revela detalles poco conocidos sobre el simbolismo sexual presente en los mitos cosmogónicos mesoamericanos. Abstract in english The birds represented at Stela 25 of Izapa and Copan ball court are the starting point for the analysis of the mythological topic focused on the vagina dentata in Ancient Mesoamerica, as well as their expressions on art and narrative. A large body of mythological narratives is used as a basis for th [...] e examination of the "Siete Guacamayo" story included in the Popol Vuh, which is interpreted as part of a widely extended myth related with the creation of the Sun and the Moon. The identification of common issues, as the vagina dentata topic, strengthens the links between the Popol Vuh myth and the Izapa and Copan representations. It also reveals less known details on the sexual symbolism included in the Mesoamerican cosmogonic myths.

  19. Mannose binding lectin and C3 act as recognition molecules for infectious agents in the vagina.

    Science.gov (United States)

    Pellis, V; De Seta, F; Crovella, S; Bossi, F; Bulla, R; Guaschino, S; Radillo, O; Garred, P; Tedesco, F

    2005-01-01

    In our study we examined the early complement components in patients with bacterial vaginosis (BV), vulvovaginal candidiasis (VVC) and in healthy controls. The levels of C1q, mannose-binding lectin (MBL) and C3 were measured by ELISA in the cervicovaginal lavage (CVL) from gynaecological patients and controls. No significant differences were observed in the levels of these proteins in the three study groups. Immunofluorescence analysis of the clue cells and Candida hyphae from BV and VVC patients for surface-bound complement components showed the presence of C3, while C1q was undetectable. MBL was revealed on clue cells but not on Candida. Binding of MBL to Candida, grown or cytocentrifuged from the CVL of VVC patients, was found to be pH dependent and occurred between pH 4.5 and pH 5.5. In conclusion, we demonstrated that MBL and C3 present in the vaginal cavity act as recognition molecules for infectious agents that colonize the cervicovaginal mucosa. Our finding that MBL, but not C1q, binds to bacteria and fungi in vagina suggests that the lectin and classical pathways of complement activation may play a different role in immune defence in the female genital tract. PMID:15606621

  20. Phospholipase activity of Candida albicans isolated from vagina and urine samples

    Directory of Open Access Journals (Sweden)

    Sanaz Miry

    2010-10-01

    Full Text Available Introduction and objective: Candida albicans is the most virulent among the Candida species, and can cause several forms of candidiasis in human. Extracellular phospholipases in C. albicans is discussed as one of the virulence factors. The present study, focused on extracellular phospholipase activities in different isolates of C. albicans isolated from vagina and urine samples from Ahvaz, Iran. In addition, phospholipase activities were compared in C. albicans isolated from two different sources. Materials and methods: In the present study, phospholipase activity of 100 isolates of C. albicans with urine and vaginitis origin was demonstrated using Sabouraud's dextrose agar supplemented with egg yolk. Results: The phospholipase activity was detected in all tested isolates with a high level in Pz<0.70. In the present study phospholipase activity with higher Pz values was more common in vaginal isolates (84.7% isolates with Pz value <0.70 compared with 75% in urine isolates. Conclusion: In the present study, 100% clinical isolates of C. albicans from vaginitis and urine samples demonstrated phospholipase activity.

  1. Tubulo-squamous polyp of the vagina with sebaceous glands: novel features in an uncommon recently described entity.

    Science.gov (United States)

    Chaturvedi, Anshuman; Padel, Adam

    2010-09-01

    Tubulo-squamous polyp of the vagina is a recently described histopathologic entity. This case report describes an as yet unreported morphologic feature of sebaceous glands in an example of this lesion. Further knowledge of the morphologic spectrum of this lesion should be of aid to histopathologists in its recognition. A brief review of currently available literature on this topic is also given. PMID:20736779

  2. Efecto del sistema de crianza (extensivo vssemiintensivo) del macho cabrío, sobre la obtención de semen mediante vagina artificial

    OpenAIRE

    Víctor Manuel Prado; Agustín Orihuela Trujillo; Salvador Lozano Trejo; María Isabel Pérez León

    2001-01-01

    Con el propósito de evaluar el efecto del sistema de crianza (extensivo vs semiintensivo) del macho cabrío, en el entrenamiento para colecta de semen mediante vagina artificial, se utilizaron ocho animales criollos, de dos años de edad, con experiencia sexual; cuatro habían sido criados bajo condiciones extensivas, y los restantes bajo un manejo semiintensivo. Todos recibieron ocho sesiones de entrenamiento, exponiéndoles en forma individual, dos veces por semana, ante una hembra ...

  3. A RARE C.T. SCAN FINDING OF FOREIGN BODY VAGINA, A HARD FRUIT, KEPT AS PESSARY FOR UTERINE PROLAPSE

    Directory of Open Access Journals (Sweden)

    Radha Rani

    2014-06-01

    Full Text Available Vaginal pessaries still have a role in the management of uterine prolapse, particularly in elderly patients. The presence of a foreign body or device in the female pelvis can be a potential source of confusion to the radiologists, particularly to the inexperienced reader. We present a rare C.T. scan finding of a hard fruit kept in vagina 5yrs back for uterine prolapse.

  4. Delivery of double singleton pregnancies in a woman with a double uterus, double cervix, and complete septate vagina.

    Science.gov (United States)

    Yang, Ming-Jie; Tseng, Jen-Yu; Chen, Chih-Yao; Li, Hsin-Yang

    2015-12-01

    Uterine anomalies involving a double uterus, double cervix, also known as didelphys uterus, and complete septate vagina are rarely seen and have an associated fertility problem. However, artificial reproductive technology with embryo transfers can help solve this fertility challenge. Conception in the uterus in just one side is commonly seen for embryos, which are always transferred through the usually used (dilated) vagina. We here present a patient with the above uterine anomaly who conceived with the aid of in vitro fertilization and embryo transfer to both uterine cavities under general anesthesia, which resulted in successful double singleton pregnancies with one fetus in each uterus. With intensive prenatal care, the pregnancy course for each fetus was rather uneventful. Although both fetuses were in cephalic presentation, cesarean section was performed at the 39(th) week of gestation with good outcomes in order to preclude anticipated difficulties if the baby had been delivered through the rarely dilated vagina. However, order of birth between the two fetuses was a crucial decision during the operation. PMID:26462956

  5. In vivo Raman spectroscopy of human uterine cervix: exploring the utility of vagina as an internal control

    Science.gov (United States)

    Shaikh, Rubina; Dora, Tapas Kumar; Chopra, Supriya; Maheshwari, Amita; Kedar K., Deodhar; Bharat, Rekhi; Krishna, C. Murali

    2014-08-01

    In vivo Raman spectroscopy is being projected as a new, noninvasive method for cervical cancer diagnosis. In most of the reported studies, normal areas in the cancerous cervix were used as control. However, in the Indian subcontinent, the majority of cervical cancers are detected at advanced stages, leaving no normal sites for acquiring control spectra. Moreover, vagina and ectocervix are reported to have similar biochemical composition. Thus, in the present study, we have evaluated the feasibility of classifying normal and cancerous conditions in the Indian population and we have also explored the utility of the vagina as an internal control. A total of 228 normal and 181 tumor in vivo Raman spectra were acquired from 93 subjects under clinical supervision. The spectral features in normal conditions suggest the presence of collagen, while DNA and noncollagenous proteins were abundant in tumors. Principal-component linear discriminant analysis (PC-LDA) yielded 97% classification efficiency between normal and tumor groups. An analysis of a normal cervix and vaginal controls of cancerous and noncancerous subjects suggests similar spectral features between these groups. PC-LDA of tumor, normal cervix, and vaginal controls further support the utility of the vagina as an internal control. Overall, findings of the study corroborate with earlier studies and facilitate objective, noninvasive, and rapid Raman spectroscopic-based screening/diagnosis of cervical cancers.

  6. VIP, vagina, clitoral and periurethral glans--an update on human female genital arousal.

    Science.gov (United States)

    Levin, R J

    1991-01-01

    The sexually quiescent human vagina is a just moist, potential space with a minimal blood flow and very low luminal oxygen tension. The first measurable sign of sexual arousal is an increase in the blood flow. This creates the engorged condition, elevates the luminal oxygen tension and stimulates the production of surface vaginal fluid by an increased plasma transudation that saturates the fluid reabsorptive capacity of the epithelium. The vaginal lubrication created allows painless penile penetration and coital movements. The mechanisms underlying the changes appear to be mediated by Vasoactive Intestinal Peptide (VIP). VIP is present in nerves closely applied to blood vessels in the vaginal wall. Administration of VIP either intravenously, or by subepithelial injection in the vaginal wall, increases vaginal blood flow and induces vaginal fluid production. Increases in vaginal blood flow by sexual arousal are not blocked by atropine injection indicating that cholinergic mechanisms are unimportant. All the present evidence suggests that the local vaginal release of VIP induces the vaginal changes of arousal. Discourse on vaginal and pudendal anatomy (Sevely, 1987) has proposed that the female glans of the clitoris is not the true homologue of the penile glans because it has no urethral opening. The speculative suggestion is that the true female glans is the area surrounding the urethral opening (which has no specific anatomical name). Preliminary studies indicate that the area of this tissue (periurethral glans) decreases on vaginal penile insertion and reappears on withdrawal indicating that it is moved during coitus. How important such movement is to stimulate erotic sensation and how sensitive this area is to erotic stimulation are unanswered questions. PMID:1778234

  7. Antibiotic resistance in Staphylococci isolated from the vaginas of captive female Leontopithecus (Callitrichidae-Primates).

    Science.gov (United States)

    Lilenbaum, Walter; Moraes, Ismar A; Cardoso, Verônica S; Varges, Renato G; Ferreira, Ana Maria R; Pissinatti, Alcides

    2006-08-01

    The purpose of this study was to provide current data on Staphylococcus species from the vaginas of clinically normal captive lion tamarins and to determine the antimicrobial susceptibility of these isolates. Samples were collected from 25 adult lion tamarins, processed to isolate Staphylococcus species, and tested for susceptibility to penicillin G, gentamicin, chloramphenicol, tetracycline, trimethoprim-sulfamethoxazole, streptomycin, ampicillin, and rifampicin. Isolates with the typical characteristics of the genus Staphylococcus were recovered from all 25 samples. Coagulase-negative species were the most common (68% of the isolates), and the most frequently isolated species (10 samples) was S. simulans. Other coagulase-negative species, including S. saprophyticus (n=5), S. epidermidis (n=1), and S. arlettae (n=1), were also recovered. Coagulase-positive Staphylococci were obtained from eight animals (six of from the S. aureus species and two from S. intermedius). Resistance to antibiotics was frequently observed, and 88% of the isolates (23 samples) showed resistance to at least one drug. Resistance to penicillin G was a common finding, and the most active antimicrobial agents were chloramphenicol and gentamicin. Coagulase-positive strains were more frequently resistant to antibiotics (79.7%, average=6.4 drugs) than coagulase-negative strains (38.2%, average=3.0 drugs). The high frequency of resistance observed in those isolates is surprising and very alarming. A detailed history of the use of antimicrobial drugs in these subjects did not reveal any previous exposure to any of the tested antibiotics that could justify the observed resistance rate. PMID:16847975

  8. The Lactobacillus flora in vagina and rectum of fertile and postmenopausal healthy Swedish women

    Directory of Open Access Journals (Sweden)

    Stjernquist Martin

    2011-05-01

    Full Text Available Abstract Background Lactobacillus species are the most often found inhabitants of vaginal ecosystem of fertile women. In postmenopausal women with low oestrogen levels, Lactobacillus flora is diminishing or absent. However, no studies have been performed to investigate the correlation between oestrogen levels and the lactobacilli in the gut. The aim of the present study was to investigate the relation in healthy women between vaginal and rectal microbial flora as well as possible variations with hormone levels. Methods Vaginal and rectal smears were taken from 20 healthy fertile women, average 40 years (range 28-49 years, in two different phases of the menstrual cycle, and from 20 postmenopausal women, average 60 years (range 52-85 years. Serum sex hormone levels were analyzed. Bacteria from the smears isolated on Rogosa Agar were grouped by Randomly Amplified Polymorphic DNA and identified by multiplex PCR and partial 16S rRNA gene sequencing. Results Lactobacillus crispatus was more often found in the vaginal flora of fertile women than in that of postmenopausal (p = 0.036. Fifteen of 20 fertile women had lactobacilli in their rectal smears compared to 10 postmenopausal women (p = 0.071. There was no correlation between the number of bacteria in vagina and rectum, or between the number of bacteria and hormonal levels. Neither could any association between the presence of rectal lactobacilli and hormonal levels be found. Conclusion Lactobacillus crispatus was more prevalent in the vaginal flora of fertile women, whereas the Lactobacillus flora of rectum did not correlate to the vaginal flora nor to hormonal levels.

  9. xpression of estrogen and progesterone receptor genes in endometrium, myometrium and vagina of postmenopausal women treated with estriol / Expresión de los genes receptores de estrógeno y progesterona en el endometrio, miometrio y vagina en mujeres posmenopáusicas tratadas con estriol

    Scientific Electronic Library Online (English)

    Magdalena, Bry& #347; ; Krzysztof, Szytto; Hanna, Romanowicz-Makowska; Zbigniew, Dobrowolski; Izabela, Mastowska; Wanda, Krajewska.

    Full Text Available CONTEXTO Y OBJETIVO: El estriol es un estrógeno con un efecto estimulatorio bastante más débil sobre la proliferación endometrial que el estradiol. Se realizó un estudio para determinar los efectos de una terapia vaginal de 14 días con estriol, sobre el nivel de receptores de estrógeno (ER) y recept [...] ores de progesterona (PR), comparado con mujeres sin esa terapia. La expresión de los genes de ER y PR se analizó en el endometrio, miometrio y vagina de mujeres posmenopáusicas tratadas con estriol. DISEÑO Y UBICACIÓN: Estudio Transversal analítico, en el Instituto de Investigación del Hospital de la Madre Polaca en Lodz, Polonia. MÉTODOS: Se incluyeron veintisiete mujeres posmenopáusicas (de 57 a 74 años) en el estudio. Todas ellas estaban en espera de una histerectomía per vaginam o de cirugía plástica de la vagina y del perineo debido a un prolapso del útero. La expresión de genes de los receptores ER y PR se estableció por la técnica de RT-PCR. RESULTS: En las pacientes tratadas con estriol en comparación con el grupo de control, se observó un aumento significativo de la expresión del gen de ER en el endometrio y la vagina, mientras que un aumento de la expresión del gen de PR se encontró en el endometrio. De todas formas, en el examen histológico del endometrio, se diagnosticó estimulación estrogénica de bajo y medio grado en el 21.4% y en el 14.3% de las mujeres tratadas con estriol, respectivamente. CONCLUSIONES: Los resultados obtenidos sugieren que un tratamiento de 14 días con estriol en pacientes, aunque aumentan el nivel de ER y de PR mRNA, tiene muy poco o ningún efecto sobre la proliferación endometrial. Abstract in english CONTEXT AND OBJECTIVE: Estriol is an estrogen with considerably weaker stimulatory effects on endometrial proliferation than estradiol. A study was conducted to determine the level of estrogen receptors (ERs) and progesterone receptors (PRs) in women who received 14-day vaginal estriol therapy, comp [...] ared with those who did not receive this therapy. ER and PR gene expression was analyzed in the endometrium, myometrium and vagina of postmenopausal women treated with estriol. DESIGN AND SETTING: Analytical cross-sectional study, at the Research Institute of the Polish Mothers' Memorial Hospital, Lodz, Poland. METHODS: Twenty-seven postmenopausal women (57-74 years of age) were included in the study. All of them were waiting for per vaginam hysterectomy or plastic surgery on the vagina and perineum because of uterine prolapse. ER and PR gene expression was determined by means of the technique of reverse transcription polymerase chain reaction (RT-PCR). RESULTS: In the estriol-treated patients, in comparison with the control group, a significant increase in ER gene expression was observed in the endometrium and vagina, while enhanced PR gene expression was found in the endometrium. However, under histological examination of the endometrium, estrogen stimulation of low and medium degree was diagnosed for 21.4% and 14.3% of the estriol-treated women, respectively. CONCLUSION: The results obtained suggest that the women who received 14 days of treatment with vaginal estriol had higher ER and PR mRNA levels. No difference between these groups regarding endometrial proliferation was observed.

  10. Avaliação dosimétrica de uma combinação de aplicadores para braquiterapia de tumores do colo uterino com acometimento da porção distal da vagina Dosimetric evaluation of a combination of brachytherapy applicators for uterine cervix cancer with involvement of the distal vagina

    Directory of Open Access Journals (Sweden)

    Roger Guilherme Rodrigues Guimarães

    2009-08-01

    Full Text Available OBJETIVO: Avaliar uma alternativa de braquiterapia para tumores do colo uterino acometendo a porção distal da vagina, sem aumentar os riscos de toxicidade. MATERIAIS E MÉTODOS: Estudo teórico comparando três diferentes aplicadores de braquiterapia intracavitária de alta taxa de dose: sonda intrauterina e cilindro vaginal (SC; sonda e anel associado ao cilindro vaginal (SA+C e um aplicador virtual com sonda, anel e cilindro vaginal em um único conjunto (SAC. Foram prescritas doses de 7 Gy no ponto A e 5 Gy na superfície ou a 5 mm de profundidade na mucosa vaginal, mantendo as doses nos pontos de reto, bexiga e sigmoide abaixo dos limites de tolerância. Foram comparados os volumes englobados pelas isodoses de 50% (V50, 100% (V100, 150% (V150 e 200% (V200, respectivamente. RESULTADOS: Tanto SA+C quanto SAC apresentaram melhor distribuição de dose quando comparados ao aplicador SC. A distribuição de dose obtida com SA+C foi semelhante à do aplicador SAC, sendo V150 e V200 cerca de 50% maiores para SA+C, todavia, dentro do cilindro. CONCLUSÃO: A utilização de SA+C em uma única aplicação em dois tempos pode ser uma alternativa de tratamento para pacientes que apresentam tumores de colo uterino com acometimento distal da vagina.OBJECTIVE: To evaluate an alternative brachytherapy technique for uterine cervix cancer involving the distal vagina, without increasing the risk of toxicity. MATERIALS AND METHODS: Theoretical study comparing three different high-dose rate intracavitary brachytherapy applicators: intrauterine tandem and vaginal cylinder (TC; tandem/ring applicator combined with vaginal cylinder (TR+C; and a virtual applicator combining both the tandem/ring and vaginal cylinder in a single device (TRC. Prescribed doses were 7 Gy at point A, and 5 Gy on the surface or at a 5 mm depth of the vaginal mucosa. Doses delivered to the rectum, bladder and sigmoid colon were kept below the tolerance limits. Volumes covered by the isodoses, respectively, 50% (V50, 100% (V100, 150% (V150 and 200% (V200 were compared. RESULTS: Both the combined TR+C and TRC presented a better dose distribution as compared with the TC applicator. The TR+C dose distribution was similar to the TRC dose, with V150 and V200 being about 50% higher for TR+C (within the cylinder. CONCLUSION: Combined TR+C in a two-time single application may represent an alternative therapy technique for patients affected by uterine cervix cancer involving the distal vagina.

  11. Melanoma amelanótico primario de vagina: reporte de un caso y revisión de la literatura

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    María Paula Houghton-Martínez

    2012-03-01

    Full Text Available Objetivo: revisar el diagnóstico clínico, histológico e inmunohistoquímico; las alternativas terapéuticas y los factores que influyen en el pronóstico del melanoma amelanocítico de vagina. Materiales y métodos: se presenta el caso de una paciente de 49 años que consultó por masa vaginal de 8 cm en pared anterior de vagina, nacarada y con fondo necrótico a la Unidad de Patología Cervical y Colposcopia del Hospital de Engativá, institución de segundo nivel de complejidad que atiende pacientes de nivel socioeconómico bajo afiliados al régimen de seguridad pública. Se realizó resección amplia de la lesión. La patología quirúrgica informó melanoma fusocelular y epiteloide maligno. Se realizó una búsqueda sistemática usando las palabras clave: melanoma primario y vagina en las bases de datos Medline vía PubMed, Cochrane y Ebsco. Resultados: se encontraron 489 artículos de los cuales 31 estaban relacionados directamente con el tema, de estos se seleccionaron diez que correspondieron a nueve reportes de caso y a una revisión del tema. El diagnóstico clínico no es fácil. Las proteínas HMB45 y S100 son de gran utilidad en su identificación. La respuesta al tratamiento quirúrgico, la radioterapia y la quimioterapia es pobre. El pronóstico depende de la ploidía, la amelanosis y el índice mitótico. Conclusiones: el melanoma primario de vagina es una neoplasia rara y de mal pronóstico. Hace parte del grupo de melanomas de mucosa que tienen un origen y comportamiento biológico diferente al cutáneo. Tiene tendencia a la diseminación hematógena rápida y a recaídas locales. El tratamiento se basa en cirugía conservadora, radioterapia, quimioterapia y terapia biológica; sin embargo, su eficacia es limitada.

  12. Dosimetric evaluation of a combination of brachytherapy applicators for uterine cervix cancer with involvement of the distal vagina; Avaliacao dosimetrica de uma combinacao de aplicadores para braquiterapia de tumores do colo uterino com acometimento da porcao distal da vagina

    Energy Technology Data Exchange (ETDEWEB)

    Guimaraes, Roger Guilherme Rodrigues [Real e Benemerita Sociedade Portuguesa de Beneficencia, Sao Paulo, SP (Brazil). Servico de Radioterapia Estereotactica; Carvalho, Heloisa de Andrade; Stuart, Silvia Radwanski; Rubo, Rodrigo Augusto [Universidade de Sao Paulo (USP), SP (Brazil). Hospital das Clinicas. Servico de Radioterapia], e-mail: handrade@hcnet.usp.br; Seraide, Rodrigo Migotto [Centro de Oncologia Campinas, SP (Brazil)

    2009-07-15

    Objective: To evaluate an alternative brachytherapy technique for uterine cervix cancer involving the distal vagina, without increasing the risk of toxicity. Materials And Methods: Theoretical study comparing three different high-dose rate intracavitary brachytherapy applicators: intrauterine tandem and vaginal cylinder (TC); tandem/ring applicator combined with vaginal cylinder (TR+C); and a virtual applicator combining both the tandem/ring and vaginal cylinder in a single device (TRC). Prescribed doses were 7 Gy at point A, and 5 Gy on the surface or at a 5 mm depth of the vaginal mucosa. Doses delivered to the rectum, bladder and sigmoid colon were kept below the tolerance limits. Volumes covered by the isodoses, respectively, 50% (V50), 100% (V100), 150% (V150) and 200% (V200) were compared. Results: Both the combined TR+C and TRC presented a better dose distribution as compared with the TC applicator. The TR+C dose distribution was similar to the TRC dose, with V150 and V200 being about 50% higher for TR+C (within the cylinder). Conclusion: Combined TR+C in a two-time single application may represent an alternative therapy technique for patients affected by uterine cervix cancer involving the distal vagina. (author)

  13. Induction of specific immunoglobulin A in the small intestine, colon-rectum, and vagina measured by a new method for collection of secretions from local mucosal surfaces.

    OpenAIRE

    Haneberg, B; Kendall, D.; Amerongen, H M; Apter, F M; Kraehenbuhl, J. P.; Neutra, M R

    1994-01-01

    In order study patterns of local antibody responses following mucosal immunization of mice via different routes, a method for collection of secretions directly from mucosal surfaces was developed. Mice were immunized on days 0, 10, 17, and 24 by administration of cholera toxin into the oral cavity, stomach, colon-rectum, or vagina. At sacrifice on day 32, absorbent wicks were placed in the oral cavity and, via an applicator tube, into the vagina and distal colon-rectum and along the entire sm...

  14. Synchronous Superficial Myofibroblastoma and Stromal polyp of the Vagina: Report of A Case Supporting Common Histogenesis of Both Lesions

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    Michal Zamecnik

    2015-06-01

    Full Text Available Rare simultaneous occurrence of vaginal superficial cervicovaginal myofibroblastoma and vaginal stromal polyp is described. The lesions were found in a 90-years-old patient, in the anterior wall of the vagina. The diameter of the lesions was 6cm and 2cm, respectively. Between them, a 3cm part of normal appearing vaginal wall was present. Both lesions showed similar myoid appearing morphology and myofibroblastic desmin+/actin-/h-caldesmon-/CD34- immunophenotype, with positivity for CD10, CD99, estrogen receptor and progesterone receptor. Larger lesion was diagnosed as benign cervicovaginal myofibroblastoma, and the smaller one had typical features of vaginal stromal polyp. This case of simultaneous occurrence of cervicovaginal myofibroblastoma and vaginal stromal polyp supports previously suggested histogenetic relationship between these lesions. [J Interdiscipl Histopathol 2015; 3(2.000: 63-67

  15. Ultrastructural study of the neovagina following the utilization of human amniotic membrane for treatment of congenital absence of the vagina

    Directory of Open Access Journals (Sweden)

    L.F. Bleggi-Torres

    1997-07-01

    Full Text Available We present an ultrastructural study of the utilization of human amniotic membrane in the treatment of congenital absence of the vagina in 10 patients. All patients were surgically treated with application of an amniotic membrane graft using the modified McIndoe and Bannister technique. Sixty days after surgery, samples of the vaginal neo-epithelium were collected for transmission electron microscopy analysis. The ultrastructural findings consisted of a lining of mature squamous epithelium indicating the occurrence of metaplasia of the amniotic epithelium into the vaginal epithelium. The cells were arranged in layers as in the normal vaginal epithelium, i.e., superficial, intermediate and deep layers. There were desmosomes and cytoplasmic intermediate cytokeratin filaments, as well as some remnant features of the previous amniotic epithelium. These findings suggest that human amniotic membrane is able to complete metaplasia into squamous cells but the mechanism of this cellular transformation is unknown

  16. Genital panics: constructing the vagina in women's qualitative narratives about pubic hair, menstrual sex, and vaginal self-image.

    Science.gov (United States)

    Fahs, Breanne

    2014-06-01

    An emerging body of research targets women's relationship to their genitals, particularly as pubic hair removal and the promotion of female genital surgeries increase in popularity and visibility. This study asked women to discuss their subjective feelings about three related but distinct genital attitudes: pubic hair grooming, sex during menstruation, and genital/vaginal self-image. Specifically, this study applied thematic analysis to qualitative interviews with a community sample of 20 women (mean age=34, SD=13.35) from diverse ages, races, and sexual identity backgrounds to illuminate seven themes in women's narratives about their vaginas: (1) "dirty" or "gross"; (2) needing maintenance; (3) unknown or frustrating; (4) unnatural; (5) comparative; (6) ambivalent; (7) affirmative. Overwhelmingly, women used strong emotional language when discussing their genitals, often evoking descriptions of anxiety, excess, and need for control. Fusions between sexuality and body image, and connections between "genital panics" and internalized racism, sexism, and homophobia, also appeared. PMID:24958655

  17. Ultrastructural features of vagina at different phases of the oestrous cycle in the female African giant rat (Cricetomys gambianus Waterhouse).

    Science.gov (United States)

    Akinloye, Adebayo K; Oke, Bankole O

    2014-06-01

    The ultrastructures of the vagina at various stages of the oestrous cycle in female African giant rats (Cricetomys gambianus Waterhouse) were described in the present study. At mid-proestrus, late proestrus (LP)/early estrus (EE) and mid-estrus (ME) as well as late metestrus (LM)/early diestrus (ED) and mid-diestrus (MD), complex interface of epithelium and lamina propria were observed. Cells of the stratum basale formed finger-like extensions into the underlying lamina propria and tips of the extensions displayed hemidesmosome while basal lamina followed the contour of the extensions. At mid-metestrus (MM) and late diestrus/early proestrus, well developed, relatively straight basal lamina interfaced between the stratum basale and the lamina propria without finger-like projections. Polygonal cells with indented nuclei and, cytoplasm containing ribosomes, polysomes, intermediate filaments, and mitochondria were observed in stratum spinosum at all the phases of the oestrus cycle. At MM, LM/ED, and MD, the stratum spinosum had numerous desmosomes with tonofilaments, large microvilli that intermingled at the intercellular spaces and evidence of trapped/migrating neutrophils and lymphocytes. The superficial layer displayed short microvilli at mid-proestrus, cornification at LP/EE and desquamation at ME while it showed condensation of intermediate filaments; projections of large microvilli into the luminal surface at MM, and embeddement of neutrophils at LM/ED as well as MD. This study looked into the reproductive biology of female African giant rats to produce baseline information on its reproductive organs and represented the first comprehensive description of the vagina at the ultrastructural level during oestrous cycle. PMID:24737725

  18. The Mayer-von Rokitansky-Küster-Hauser syndrome (uterus bipartitus solidus rudimentarius cum vagina solida): the development of gynecology through the history of a name.

    Science.gov (United States)

    Ghirardini, G; Popp, L W

    1995-01-01

    A summary of the original descriptions of the Authors who gave the name to the syndrome characterized by absence of uterus and vagina is presented. Through these original descriptions a complete view of the development in gynecology over the last 150 years is offered. PMID:7736648

  19. Nonoxynol-9 berberine plural gel has little effect on expression of SLPI, SP-D and lactoferrin in mice’s vagina

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    Huang Guangying

    2013-01-01

    Full Text Available Background: The most frequently used spermicide Nonoxynol-9 (N-9 in the clinic alters the vaginal flora, which will result in an increased risk of opportunistic infection. So development of a novel spermicidal and microbicidal drug appears to be inevitable. Vaginal local immune is an important part of vaginal flora. Secretory leukocyte protease inhibitor (SLPI, surfactant proteins D (SP-D, and lactoferrin (LF are anti-microbial molecules with important roles in immune system of female vaginas. Objective: To observe effect of a vaginal spermicide nonoxynol-9 (N-9 berberine plural gel on the expression of SLPI SP-D and LF in mice’s vaginas. Materials and Methods: Female BABL/C mice were randomly divided into following 5 groups: normal control group, blank gel group, berberine gel group, 12% N-9 gel group and N-9 berberine plural gel group. Estradiol benzoate at physiological dose was done by hypodermic injection to every group’s mice. After 72h, drug gels were separately injected into the mice’s vaginas, while immunohistochemistry and Western blot were taken to detect the expression of the 3 indexes in mice’s vaginas respectively after 24h and 72h of gel injection. Results: The differences in the three indexes between normal control group and blank gel group were not significant statistically (p>0.05. The expression of the three indexes in 12% N-9 gel group was decreased compared to that in blank gel group (p0.05. Also, the three index's level of 24h and 72h in sub observation groups after treatment were without statistical significance (p>0.05. Conclusion: Application of N-9 berberine plural gel had little impact on antimicrobial peptides in normal mice’s vaginas.

  20. Caracterização de leveduras isoladas da vagina e sua associação com candidíase vulvovaginal em duas cidades do sul do Brasil Characterization of yeasts isolated from the vagina and their association with vulvovaginal candidíasis in two cities of the South of Brazil

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    Magda Helena S. H. Ferrazza

    2005-02-01

    Full Text Available OBJETIVOS: avaliar a distribuição de espécies de leveduras isoladas da vagina em duas localidades do sul do Brasil e comparar o perfil de suscetibilidade in vitro destas leveduras a antifúngicos usados na prática clínica. MÉTODOS: todas as mulheres atendidas entre janeiro e junho de 2004 para exames rotineiros de amostras vaginais, independente de serem sintomáticas ou não, foram incluídas neste estudo. Foram excluídas as que apresentavam imunodeficiências como AIDS ou outras infecções genitais. Amostras de conteúdo vaginal dessas mulheres (Jaraguá do Sul - SC (n=130 e Maringá - PR (n=97 foram cultivadas. As leveduras isoladas foram identificadas e submetidas ao teste de suscetibilidade aos antifúngicos fluconazol, nistatina e anfotericina B. RESULTADOS: a freqüência de cultura positiva para levedura foi semelhante nas duas localidades, aproximadamente 24%. Candida albicans foi a espécie prevalente, mas sua freqüência diferiu: em SC correspondeu a 77,4% das leveduras e foi a mais freqüente tanto nas mulheres sintomáticas quanto nas assintomáticas. Já no PR foi 50,0%, com predomínio mais evidente nos casos sintomáticos. Observamos altos índices de suscetibilidade ao fluconazol e anfotericina B, porém 51,1% das leveduras apresentaram suscetibilidade dependente da dose (S-DD para nistatina. C. albicans mostrou maior tendência de resistência à nistatina (52,8% de S-DD do que as espécies não-albicans (44,4%. CONCLUSÕES: nossos dados mostram diferenças regionais quanto à espécie de levedura em amostras vaginais. Sugerem que a determinação da espécie pode ter implicação clínica, considerando as diferenças quanto à suscetibilidade, principalmente à nistatina, e que poderiam ter importância no manejo da candidíase vulvovaginal.PURPOSE: to evaluate the distribution of yeast species isolated from the vagina in two cities of the South of Brazil and compare the in vitro susceptibility profile of these yeasts against some antifungals, which are used in clinical routine. METHODS: all women attended from January to June 2004 for vaginal routine examinations, independent of being symptomatic or not were included in the study. Only those who presented immunodeficiency like AIDS or any other genital infection were excluded. Samples of vaginal discharge from the women (Jaraguá do Sul - SC (n=130 and Maringá - PR (n=97 were cultivated. The yeasts were identified and submitted to the susceptibility test against the antifungals fluconazole, nystatin and amphotericin B. RESULTS: the frequency of positive cultures for yeasts was the same in both cities; C. albicans was the most prevalent species (about 24%, but its frequency was different: in SC it corresponded to 77.4% of the yeasts both in symptomatic and asymptomatic women and in PR it was 50.0% with predominance in symptomatic women. We observed high rates of susceptibility to fluconazole and amphotericin B, but 51.1% of the yeasts presented dose-dependent susceptibility (DDS to nystatin. C. albicans showed a higher tendency to be nystatin resistant (52.8% DDS than non-albicans species (44.4%. CONCLUSIONS: our data showed geographic differences among the species of yeasts isolated from the vagina and suggest that this fact has clinical relevance considering the differences in susceptibility, especially regarding nystatin, which could be important for the management of vulvovaginal candidiasis.

  1. Rapidly disintegrating vagina retentive cream suppositories of progesterone: development, patient satisfaction and in vitro/in vivo studies.

    Science.gov (United States)

    Bendas, Ehab Rasmy; Basalious, Emad B

    2016-05-01

    Our objective was to develop novel vagina retentive cream suppositories (VRCS) of progesterone having rapid disintegration and good vaginal retention. VRCS of progesterone were prepared using oil in water (o/w) emulsion of mineral oil or theobroma oil in hard fat and compared with conventional vaginal suppositories (CVS) prepared by hard fat. VRCS formulations were tested for content uniformity, disintegration, melting range, in vitro release and stability studies. The most stable formulation (VRCS I) was subjected to scaling-up manufacturing and patients' satisfaction test. The rapid disintegration, good retentive properties are applicable through the inclusion of emulsified theobroma oil rather than hydrophilic surfactant into the hard fat bases. The release profile of progesterone from VRCS I showed a biphasic pattern due to the formation of progesterone reservoir in the emulsified theobroma oil. All volunteers involved in patients' satisfaction test showed high satisfactory response to the tested formulation (VRCS). The in vivo pharmacokinetic study suggests that VRCS of progesterone provided higher rate and extent of absorption compared to hard fat based suppositories. Our results proposed that emulsified theobroma oil could be promising to solve the problems of poor patients' satisfaction and variability of drug absorption associated with hard fat suppositories. PMID:25567033

  2. Diversity of the Lactobacillus group in breast milk and vagina of healthy women and potential role in the colonization of the infant gut

    OpenAIRE

    de Martin, R; Heilig, G.H.J.; Zoetendal, E.G.; Smidt, H.; Rodriguez, J. M.

    2007-01-01

    Aims: To evaluate the diversity of the Lactobacillus group in breast milk and the vagina of healthy women and understand their potential role in the infant gut colonization using the 16S rRNA gene approaches. Methods and Results: Samples of breast milk, vaginal swabs and infant faeces were aseptically collected from five mothers whose neonates were born by vaginal delivery and another five that had their babies by caesarean section. After polymerase chain reaction (PCR) amplification using L...

  3. Effects of age, egg-laying activity, and Salmonella-inoculation on the expressions of gallinacin mRNA in the vagina of the hen oviduct.

    Science.gov (United States)

    Yoshimura, Yukinori; Ohashi, Hiroki; Subedi, Kalpana; Nishibori, Masahide; Isobe, Naoki

    2006-04-01

    Gallinacins (Gal) are antimicrobial peptides that play significant roles in innate immunity in chickens. The aim of this study was to examine whether age of birds and egg-laying activity (laying and non-laying caused by feed-regulation) affect the mRNA expression of Gal-1, -2, and -3 in the vagina of hens, and whether their expressions are changed in response to the stimulation with Salmonella enteritidis (SE) and lipopolysaccharide (LPS). White Leghorn hens were divided into groups of young and old laying hens, and groups of laying and non-laying hens after feed-regulation. Vaginal cells were cultured and stimulated with SE or LPS. Expressions of Gal-1, -2, and -3 mRNA in their vaginal mucosa and cultured cells were examined by quantitative real-time RT-PCR. The expressions of Gal-1, -2, and -3 of the vaginal mucosa were significantly greater in old birds than in young birds. Expression of these Gals in the vagina were decreased in the regressed oviduct of non-laying birds compared with laying birds. The expressions of Gal-1, -2, and -3 in the cultured vaginal cells were increased by stimulation with SE or LPS within 24 h. These results suggest that the mRNA expressions of Gal-1, -2 and -3 in the vagina of laying hens increased with age, whereas they decreased in the regressed oviduct during the non-laying phase. Also, synthesis of these antimicrobial peptides in the vagina may increase in response to SE and LPS to eliminate SE bacteria. PMID:16394622

  4. Quantitative determination by real-time PCR of four vaginal Lactobacillus species, Gardnerella vaginalis and Atopobium vaginae indicates an inverse relationship between L. gasseri and L. iners

    Directory of Open Access Journals (Sweden)

    Tagg John R

    2007-12-01

    Full Text Available Abstract Background Most studies of the vaginal microflora have been based on culture or on qualitative molecular techniques. Here we applied existing real-time PCR formats for Lactobacillus crispatus, L. gasseri and Gardnerella vaginalis and developed new formats for Atopobium vaginae, L. iners and L. jensenii to obtain a quantitative non culture-based determination of these species in 71 vaginal samples from 32 pregnant and 28 non-pregnant women aged between 18 and 45 years. Results The 71 vaginal microflora samples of these women were categorized, using the Ison and Hay criteria, as refined by Verhelst et al. (2005, as follows: grade Ia: 8 samples, grade Iab: 10, grade Ib: 13, grade I-like: 10, grade II: 11, grade III: 12 and grade IV: 7. L. crispatus was found in all but 5 samples and was the most frequent Lactobacillus species detected. A significantly lower concentration of L. crispatus was found in grades II (p L. jensenii was found in all grades but showed higher concentration in grade Iab than in grade Ia (p = 0.024. A. vaginae and G. vaginalis were present in high concentrations in grade III, with log10 median concentrations (log10 MC, respectively of 9.0 and 9.2 cells/ml. Twenty (38.5% of the 52 G. vaginalis positive samples were also positive for A. vaginae. In grade II we found almost no L. iners (log10 MC: 0/ml but a high concentration of L. gasseri (log10 MC: 8.7/ml. By contrast, in grade III we found a high concentration of L. iners (log10 MC: 8.3/ml and a low concentration of L. gasseri (log10 MC: 0/ml. These results show a negative association between L. gasseri and L. iners (r = -0.397, p = 0.001 and between L. gasseri and A. vaginae (r = -0.408, p Conclusion In our study we found a clear negative association between L. iners and L. gasseri and between A. vaginae and L. gasseri. Our results do not provide support for the generally held proposition that grade II is an intermediate stage between grades I and III, because L. gasseri, abundant in grade II is not predominant in grade III, whereas L. iners, abundant in grade III is present only in low numbers in grade II samples.

  5. Characterisation of the bacterial microbiota of the vagina of dairy cows and isolation of pediocin-producing Pediococcus acidilactici

    Directory of Open Access Journals (Sweden)

    Wang Yvonne

    2013-01-01

    Full Text Available Abstract Background Uterine infections in dairy cows lower profitability of dairy operations. Infections of the reproductive tract are related to the overgrowth of pathogenic bacteria during the first three weeks after parturition. However, alterations in the vaginal microbiota composition in the first weeks after parturition remain poorly documented. Results In this study, bacteria isolated from the vagina of healthy pregnant, and infected postpartum cows were characterised by random amplification of polymorphic DNA (RAPD analysis and partial 16S ribosomal RNA (rDNA gene sequencing. Populations of bacilli and lactic acid bacteria of the genera Enterococcus, Lactobacillus, and Pediococcus were present in both healthy and infected cows. Infected cows had a significant increase in the vaginal enteric bacteria population which consisted mainly of Escherichia coli. Three E. coli isolates harboured the gene coding for Shiga-like-toxin (SLT I or II. Several isolates of the Pediococcus acidilactici were found to produce the bacteriocin pediocin AcH/PA-1. Quantitative PCR analyses of vaginal mucus samples collected from ten metritic cows before and after parturition confirmed the presence of the Lactobacillus group (Lactobacillus spp., Pediococcus spp., Leuconostoc spp., and Weissella spp.; Enterobacteriaceae, E. coli, and bacilli. The presence of the pediocin AcH/PA-1 structural gene and SLT genes were also confirmed with qPCR. Conclusions In conclusion, overgrowth of pathogenic bacteria, particularly E. coli, after parturition likely contributes to the development of metritis. Our microbiota analysis extends the information related to the composition of commensal bacteria in the bovine female reproductive tract and may facilitate the development of novel intervention strategies for prevention of uterine infections in dairy cows.

  6. Non-leukemic myeloid sarcoma involving the vulva, vagina, and cervix: a case report and literature review

    Science.gov (United States)

    Yu, Yuan; Qin, Xuemei; Yan, Shuxin; Wang, Wenxia; Sun, Yanlin; Zhang, Maohong

    2015-01-01

    Myeloid sarcoma (MS) is defined as a tumor mass consisting of myeloid blast with or without maturation occurring at an anatomical site other than bone marrow with normal architectural effacement. It can also precede the onset of leukemia which is called non-leukemic MS. Non-leukemic MS is a kind of rare disease and easy to be misdiagnosed as other common malignancies due to the rarity and nonspecific manifestation. We herein report an unusual case of non-leukemic MS involving the vulva, vagina, and cervix in a female patient. The bone marrow aspiration and biopsy of the patient revealed no hematological abnormality. Immunohistochemical staining of the biopsies was strongly positive for myeloperoxidase, CD68, leukocyte common antigen (LCA), CD117, CD34, CD38, CD79a, and negative for cytokeratin (CK), epithelial memberane antigen (EMA), CD2, CD3, CD20, CD5, CD138. Then a diagnosis of non-leukemic MS was made. Unfortunately, our patient received only one cycle of chemotherapy consisting of cytosine arabinoside and daunorubicin, then refused any further treatment and died 4 months after diagnosis. Although systemic chemotherapy is widely accepted to be a promising strategy, its benefit still needs to be further assessed. Certain questions still need to be answered for this disease: 1) Why can approximately 20% of the patients with non-leukemic MS remain disease-free after local therapy alone? 2) How many cycles of chemotherapy are needed for these patients after achievement of complete remission? 3) What are the prognostic or risk factors in these patients who have no abnormality of karyotype, fusion genes, or gene mutation to predict responsiveness to chemotherapy and outcome? 4) What is the risk factor for relapse? The rarity of non-leukemic MS makes it almost impossible to conduct large-scale randomized trials, but judicious study for each patient with MS is helpful for a further understanding of the nature of the disease. PMID:26677338

  7. Il Linguaggio della Vagina

    OpenAIRE

    Marco Menicocci

    2011-01-01

    La cultura delle masse è oggi una cultura prevalentemente visuale. Tra i segni visuali da tempo in crescita è quello, caratteristico, della depilazione pubica femminile. Originata all'interno della cultura porno come segno di passività, questa pratica si è incontrata con i simboli della pulizia, dell'igiene, del rispetto, trasformando così il proprio significato in quello di autonomia e libertà. Così le donne possono depilarsi per scopi erotici minimizzando però la valenza sessuale del gesto ...

  8. Il Linguaggio della Vagina

    Directory of Open Access Journals (Sweden)

    Marco Menicocci

    2011-12-01

    Full Text Available La cultura delle masse è oggi una cultura prevalentemente visuale. Tra i segni visuali da tempo in crescita è quello, caratteristico, della depilazione pubica femminile. Originata all'interno della cultura porno come segno di passività, questa pratica si è incontrata con i simboli della pulizia, dell'igiene, del rispetto, trasformando così il proprio significato in quello di autonomia e libertà. Così le donne possono depilarsi per scopi erotici minimizzando però la valenza sessuale del gesto tramite la tendenza alla super-igiene.

  9. Conceptual knowledge of vesico-vagina fistula among parents, teachers and counsellors of senior secondary students in Warri South local government area of Delta State, Nigeria

    Directory of Open Access Journals (Sweden)

    Imoukhede M.O

    2015-04-01

    Full Text Available Background: VVF is leakages of urine and faeces through the vagina. It is rampant in the North and the Eastern parts of Nigeria due to the forced marriage of girls at about the age of eleven. This may be attributed to their small pelvises which have resulted in harmful reproductive health practice. The disability and suffering from obstetric fistula remains a neglected issue in global health. Aim: This study seeks to explore the conceptual knowledge of vesico-vagina fistula (VVF among parents, teachers and counselors of senior secondary school students in Warri South local government area of Delta state. Methods: A survey design was used. Random sampling method was used to select a total number of six hundred respondents including parents, teachers and counselors that participated in the study, but only five hundred and eleven questionnaires were retrieved. The questionnaire was divided into two sections containing information on demography and selected variables for the study. Data was analyzed using descriptive statistics of Anova and t-tests. Result: the study revealed that there is no significant difference in the conceptual knowledge of VVF among parents, teachers and counselors of senior secondary school students either by educational status or location. Conclusion: It can be concluded that parents, teachers and counselors of senior secondary school have very little knowledge about VVF. There is need for educational programmes on VVF to enlighten them about VVF and the danger it poses.

  10. Normal tissue tolerance to external beam radiation therapy: The vagina; Dose de tolerance a l'irradiation des tissus sains: le vagin Normal

    Energy Technology Data Exchange (ETDEWEB)

    Magne, N. [Unite de curietherapie, departement de radiotherapie, institut de cancerologie de la Loire, 42 - Saint-Priest-en-Jarez (France); Chargari, C. [Service d' oncologie radiotherapie, hopital d' instruction des armees du Val-de-Grace, 75 - Paris (France); Pointreau, Y. [Clinique d' oncologie radiotherapie, centre Henry-S.-Kaplan, hopital de Bretonneau, CHU de Tours, 37 - Tours (France); Haie-Meder, C. [Service de curietherapie, departement de radiotherapie, institut Gustave-Roussy, 94 - Villejuif (France)

    2010-07-15

    The vagina is a virtual cavity involved in sexual reproduction field. Due to its anatomical location, it may be exposed in whole or in part to ionizing radiation in external radiotherapy and/or brachytherapy of the pelvic region. This review aims to describe the vaginal acute and late side effects due to radiation, probably inadequately reported in the literature. Medline and PubMed literature searches were performed using the keywords -vaginal - radiotherapy - toxicity. The acute and late functional changes after external beam radiation consist mainly of drought. Their incidences are poorly described in the literature and the delivered doses even less. Recommendations are non-existent as the normal tissue complication probability (NTCP). Brachytherapy delivers high and heterogeneous doses, making it difficult to estimate the dose. The concomitant administration of chemotherapy appears to be a factor increasing the risk of toxicity. Modern techniques of conformal radiotherapy with modulated intensity appear to have little impact on this body. Only a maximum dose on each third of the vagina appears to be currently proposed to avoid the risk of side effects. (authors)

  11. Histologia e morfometria das glândulas das junções infundíbulo-magno e útero-vagina de codorna doméstica Histology and morphometry of the infundibulum-magnum and uterus-vaginal junctions of spotted quails

    Directory of Open Access Journals (Sweden)

    Carime Moraes

    2009-04-01

    Full Text Available A análise comparativa das glândulas armazenadoras de espermatozóides das junções infundíbulo-magno e útero-vagina do oviduto da codorna Nothura maculosa foi realizada durante a fase reprodutiva. As aves foram eutanasiadas por inalação com éter etílico, após a pesagem. Após a laparotomia e o deslocamento cranial do esterno, foram coletadas amostras de dois centímetros da junção infundíbulo-magno e útero-vagina. Os fragmentos foram fixados em solução de Bouin por 24 horas e, posteriormente, banhos sucessivos de álcool 70% foram aplicados sobre as amostras. Em seguida, as amostras foram desidratadas em uma série de concentração crescente de alcoóis (80, 90, 95 e 3x100%, diafanizadas em xilol e incluídas em parafina. Cortes histológicos de sete micrômetros de espessura foram obtidos e corados pela técnica da Hematoxilina-eosina (HE, que foram analisados e fotomicrografados em um fotomicroscópio Olympus BX-50. Para a análise morfométrica, foram capturadas imagens das glândulas armazenadoras de espermatozóides da junção infundíbulo-magno e útero-vagina mediante o programa computacional "Image Pro Plus 4.1" da Cibernetics do Brasil, tornando-se possível a quantificação das mesmas. A mucosa da junção infundíbulo-magno apresentou pregas estreitas no infundíbulo e largas no magno, enquanto na junção útero-vagina mostrou-se amplamente pregueada na vagina e mais lisa na porção uterina. O número médio de glândulas armazenadoras de espermatozóides na junção infundíbulo-magno foi maior (11,7 glândulas (PThe comparative analysis of sperm-host glands of infundibulum-magnum and uterus-vagina junctions of Nothura maculosa quail oviduct was done during the reproductive phase. The birds were euthanized with ethyl ether after weight data were taken. After abdominal laparotomy and cranial displacement of the breastbone, two centimeters samples of infundibulum-magnum and uterus-vagina junctions were collected. The samples were fixed in Bouin's solution for twenty four hours and later, successive baths of alcohol 70% were applied on samples and soon afterwards dehydrated in a series of grow concentration alcohols (80, 90, 95 and 3x100%, diaphanized in xylol and included on paraffin. Histological sections with seven micrometers thickness were obtained and stained on Haematoxylin-Eosin (HE technique, then they were analyzed and photomicrographed in a photomicroscope Olympus BX-50. For the morphometry analysis, infundibulum-magnum junctions and uterus-vagina sperm host gland images were captured through a computacional program Image Pro Plus 4.1", Cibernetics Brazil, making it possible to quantify them. The mucosa of the infundibulum-magnum junction presented very narrow folds in the infundibulum and too large in the magnum, while in the uterus-vagina junction was observed widely folds mucous in the vagina and smoother in the uterine portion. The average of sperm host gland in the infundibulum-magnum junction was higher (11.7 glands (P<0.01 compared to the uterus-vagina junction (7.5 glands. It is supposed that the abundance number of sperm host glands in infundibulum-magnum junction allows faster access of the oocyte, after the ovulation of the host spermatozoid ensuring the fertilization.

  12. Radiation therapy of cancer of the cervix, corpus uteri and vagina at the 1st University Clinic of Gynaecology in Vienna from 1950 to 1979

    International Nuclear Information System (INIS)

    On the occasion of the 30th anniversary of the department of radiotherapy of th 1st University-Clinic of Gynaecology and Obstetrics in Vienna, the results obtained in the treatment of gynaecologic malignancy are presented. During this period, more than 10 000 malignant tumors of the female genital tract were treated, including 3605 cases of cancer of the cervix, 1412 endometrial carcinomas and 397 cases of cancer of the vagina. The principal method of irradiation was local application of radium. Dosage was established empirically after measurements on a model. In addition conventional percutaneous roentgen therapy was used until 1972, when telecobalt irradiation equipment was put into use. Five-year survival rates for cervical, endometrial and vaginal cancer are presented for the years from 1950 through 1972. These results are attributed primarily to intracavitary radium application. Of 2687 cases with cervical cancer 1222 (45.5%) were alive after five years, in stage III cervical cancer 535 out of 1321 (40.5%). The latest international tables published in the Annual Report give a five-year survival rate of 31.7% for stage-III cancer of the cervix. Of 994 cases of endometrial cancer 473 were alive after five years (49.8%), while the Annual Report gives a five-year survival rate of 39.0% for primary irradiation in endometrial cancer. For cancer of the vagina, our five-year survival rate was 42.8% (127 patients out of a total of 297), while the Annual Report gives 37.3%. This demonstrates, that the results obtained at the department of radiotherapy of the 1st University Clinic of Gynaecology and Obstetrics in Vienna are better than the international average. Apart from the different methods of treatment the importance of primary radiation therapy in gynaecologic oncology is pointed out, and the side effects and complications are discussed. (orig.)

  13. Effects of depomedroxyprogesterone acetate on the development and maintenance of Candida albicans in the vagina of oophorectomized Wistar rats (Rattus norvegicus)

    Scientific Electronic Library Online (English)

    Agenor, Storti-Filho; Edilson, Damke; Márcia Aparecida, Carrara; Marcia Regina, Batista; Lucélia, Donatti; Cinthia Gandolfi, Boer; Terezinha Inez Estivalet, Svizdinski; Márcia Edilaine Lopes, Consolaro.

    2011-03-01

    Full Text Available O objetivo do presente estudo foi determinar os efeitos do acetato de depomedroxyprogesterona (ADMP) no desenvolvimento e manutenção de Candida albicans na vagina de ratas Wistar ooferectomizadas. Os animais foram divididos em grupos controle negativos (GCN), que receberam injeções de salina estéril [...] ; grupos controle positivos (GCP), que receberam injeções de valerato de estradiol; e grupos progesterona (GP), nos quais foram feitas injeções de Depo-Provera®. Após uma semana da aplicação hormonal, foi induzida a infecção vaginal por C. albicans em todos os grupos, detectada por cultura para leveduras vaginais e esfregaço de Papanicolaou. Foram feitas ainda imagens por microscopia eletrônica de varredura e transmissão para confirmar a infecção pela levedura no GP. Foram observados diferentes níveis de progesterona em GP, entre os valores basais e após a indução hormonal (P Abstract in english The objective of this study was to determine the effect of medroxyprogesterone acetate (DMPA) on the development and maintenance of Candida albicans in the vagina of oophorectomized Wistar rats. The animals were divided into negative control groups (NCG), which received injections of sterile saline; [...] positive control groups (PCG), which were given injections of estradiol valerate; and progesterone groups (PG), which were given injections of Depo-Provera®. After one week of hormonal induction, vaginal infection by C. albicans was induced in all the groups and detected by vaginal yeast culture and Papanicolaou smear. In addition, scanning and transmission electron microscopy images were obtained to confirm the vaginal infection by yeast in PG. A difference in progesterone levels in PG was observed between the basal level and after hormonal induction (P

  14. Histometric Parameters of Uterus and Vagina in Breeder Female Rabbits on the Day After Weaning According to the Ordinal Number of Parturitions / Parámetros Histométricos en Útero y Vagina de Conejas Reproductoras en el día Posterior al Destete Según el Número Ordinal de Partos

    Scientific Electronic Library Online (English)

    José Alfonso, Banda-Herrera; Jesús, Aragón Hernández; Reyes, López Ordaz; Jorge, Hernández Espinosa; Mario, Pérez-Martínez.

    2014-06-01

    Full Text Available El objetivo del presente estudio fue determinar en conejas Nueva Zelanda el efecto del número ordinal de partos sobre algunos parámetros histológicos, en el día posterior al destete. A partir de hembras de primero, segundo y tercer parto se obtuvieron fragmentos de tejido uterino y vaginal los que s [...] e procesaron mediante la técnica de inclusión en parafina para efectuar cortes histológicos. En ocho campos microscópicos capturados con una cámara conectada a un microscopio óptico se midió la altura del epitelio luminal y glandular del endometrio; el grosor del epitelio de la vagina y del miometrio. A partir de los resultados obtenidos se concluye que existen diferencias significativas (p Abstract in english The objective of this study was to establish in New Zealand female rabbits, the effect of ordinal number of parturitions on some histological parameters on the day after weaning. Tissue fragments of uterus and vagina were obtained from females of first, second and third parturitions and were process [...] ed imbedding them in paraffin in order to do histological cuts. In eight microscope fields captured by a camera connected to an optic microscope, the lumen and glandular endometrial epithelium height, as well as the thickness of vaginal and myometrium epithelium thickness were measured. From the results that were obtained it was concluded that there are significant differences (p

  15. Effect of semen collection by transrectal massage of accessory sexual glands or artificial vagina on the outcome of breeding soundness examinations of Italian yearling beef bulls.

    Science.gov (United States)

    Sylla, Lakamy; Palombi, Claudio; Stradaioli, Giuseppe; Vagniluca, Antonio; Monaci, Maurizio

    2015-03-15

    Although semen quality is one of the major traits that influence breeding soundness examination outcomes in bulls, field conditions occasionally do not allow for the collection of semen samples by means of an artificial vagina. The aims of the present study were to report the results of a large number of semen collections that were performed via the transrectal massage (TRM) of the accessory sexual glands of Italian yearling beef bulls and compare this semen collection method to the artificial vagina (AV) method in term of breeding soundness examination outcomes; furthermore, we determined whether the breed affected the semen characteristics. In the TRM group (n = 475), the semen samples were collected via TRM of the accessory sexual glands, and in the AV group (n = 502), the AV method was used. In the TRM group, semen samples were obtained from 81.3% of the bulls and penile protrusion was observed in 87.6% of the animals during semen collection. The sperm concentrations (920.5 ± 439.0 vs. 281.0 ± 259.8 × 10(6)/mL) and the percentages of total abnormal spermatozoa (22.8 ± 15.0 vs. 18.8 ± 12.9) were significantly higher in the AV group than those in the TRM group. The percentage of bulls that did not meet the minimum requirement for normal cells (?70%) was 6.2% higher in the AV group than that in the TRM group (P < 0.05). Moreover, the samples collected from Chianina bulls by TRM exhibited a lower percentage of motile sperm and a higher percentage of abnormal spermatozoa when compared with the other two breeds. The major drawbacks of the TRM technique were the inability to conduct complete evaluation of the libido and mating ability of the yearling bulls, a significant reduction of the number of spermatozoa collected, and an increase in the variability of the semen characteristics due to breed. In conclusion, despite the drawbacks, TRM guarantees that semen evaluation can be conducted in cases in which the semen samples cannot be collected with the AV method. PMID:25488791

  16. HUBUNGAN AKTIVITAS SEKSUAL PADA USIA DINI, PROMISKUITAS DAN BILAS VAGINA DENGAN KEJADIAN KANKER LEHER RAHIM PADA PASIEN ONKOLOGY DI RSUD Dr.MOEWARDI SURAKARTA

    Directory of Open Access Journals (Sweden)

    . Ridhaningsih

    2013-04-01

    Full Text Available Background: Cervical cancer ranks the top cause of cancer deaths in developing countries. At Dr. Moewardi Hospital Surakarta cervical cancer was found in most cancers. Risk factors associated with health and cleanliness of the female reproductive tract can increase the incidence of cervical cancer. Purpose this study aims to determine factors associated with female reproductive health tract and the occurrence of cervical cancer. Method: The study was a quantitative analytical research used cross sectional design. Data used primary data from interviews and secondary data from medical records. Bivariate analysis using chi square test used to prove the hypothesis. Results: Statistical analysis by chi square test for sex at an early age got p value=0,382 and the prevalence ratio= 1,375, for promiscuity with incidence cervical cancer got p value=0,481 and prevalence ratio=1,314, for vaginal douching with incidence cervical cancer got p value=0,121 and prevalence ratio=0,571. Conclusion: There was no significant correlation between sex on early age with incidence of cervical cancer, there was no significant correlation between promiscuity with incidence of cervical cancer, there was no significant correlation between vaginal douching with incidence of cervical cancer at Dr. Moewardi Hospital Surakarta on Mey until Juny 2010. Key words: sex at an early age, promiscuity, rinse the vagina, cervix cancer

  17. Can local application of imiquimod cream be an alternative mode of therapy for patients with high-grade intraepithelial lesions of the vagina?

    Science.gov (United States)

    Haidopoulos, D; Diakomanolis, E; Rodolakis, A; Voulgaris, Z; Vlachos, G; Intsaklis, A

    2005-01-01

    The aim of the present study was to assess the local application of imiquimod cream 5% as an alternative mode of therapy for high-grade vaginal intraepithelial neoplasia (VAIN 2/3). Positive human papillomavirus (HPV) patients with multifocal high-grade VAIN (2/3) not involving the vaginal vault in hysterectomized patients took part in this study. The treatment consisted of vaginal application of the cream under colposcopic guidance. Following management, biopsies were obtained from the previously recorded lesions. p53 expression was recorded prior and after therapy. Seven patients with VAIN 2/3 took part in this study. Six patients (86%) were positive for high-risk HPV type while three (43%) women who were positive for p53 nuclei prior to therapy were found to be negative following treatment. After treatment, 86% of the patients were found to have either HPV infection or low-grade VAIN. During follow-up, two patients (28.5%) were managed by vaginectomy, one for persistent and one for recurrent high-grade VAIN. Currently, from the five patients that are followed, three have simple HPV infection and two, VAIN 1. Imiquimod cream 5% might represent an alternative although not permanent method of management in young, HPV-positive women with multifocal high-grade lesions of the vagina (VAIN 2/3). PMID:16174242

  18. A multi-platform metabolomics approach identifies highly specific biomarkers of bacterial diversity in the vagina of pregnant and non-pregnant women.

    Science.gov (United States)

    McMillan, Amy; Rulisa, Stephen; Sumarah, Mark; Macklaim, Jean M; Renaud, Justin; Bisanz, Jordan E; Gloor, Gregory B; Reid, Gregor

    2015-01-01

    Bacterial vaginosis (BV) increases transmission of HIV, enhances the risk of preterm labour, and is associated with malodour. Clinical diagnosis often relies on microscopy, which may not reflect the microbiota composition accurately. We use an untargeted metabolomics approach, whereby we normalize the weight of samples prior to analysis, to obtained precise measurements of metabolites in vaginal fluid. We identify biomarkers for BV with high sensitivity and specificity (AUC?=?0.99) in a cohort of 131 pregnant and non-pregnant Rwandan women, and demonstrate that the vaginal metabolome is strongly associated with bacterial diversity. Metabolites associated with high diversity and clinical BV include 2-hydroxyisovalerate and ?-hydroxybutyrate (GHB), but not succinate, which is produced by both Lactobacillus crispatus and BV-associated anaerobes in vitro. Biomarkers associated with high diversity and clinical BV are independent of pregnancy status, and were validated in a blinded replication cohort from Tanzania (n?=?45), where we predicted clinical BV with 91% accuracy. Correlations between the metabolome and microbiota identified Gardnerella vaginalis as a putative producer of GHB, and we demonstrate production by this species in vitro. This work illustrates how changes in community structure alter the chemical composition of the vagina, and identifies highly specific biomarkers for a common condition. PMID:26387596

  19. Detection of the Human 70-kD and 60-kD Heat Shock Proteins in the Vagina: Relation to Microbial Flora, Vaginal pH, and Method of Contraception

    Directory of Open Access Journals (Sweden)

    S. S. Witkin

    1999-01-01

    Full Text Available The expression of the 60-kD and 70-kD heat shock proteins (hsp60 and hsp70 in the vaginas of 43 asymptomatic women of reproductive age with or without a history of recurrent vulvovaginitis (RVV were compared. Vaginal wash samples were obtained and assayed by enzyme-linked immunosorbent assay (ELISA for human hsp60 and hsp70. Heat shock protein 70 was not detected in any of the 19 women with no history of RVV, and hsp60 was present in only one woman in this group. In contrast, in the RVV group, 11 (45.8% were hsp60-positive and eight (33.3% were hsp70-positive. The presence of either heat shock protein in the vagina was associated with an elevated vaginal pH (>4.5. Bacterial vaginosis or Candida was identified in some of the asymptomatic subjects; their occurrence was significantly higher in women with vaginal hsp70 than in women with no heat shock proteins. Oral contraceptives were used by 35.7% of subjects who were negative for vaginal heat shock proteins, as opposed to only 12.5% of women who were positive for hsp70 and 8.3% who were positive for hsp60. Expression of heat shock proteins in the vagina may indicate an altered vaginal environment and a susceptibility to vulvovaginal symptoms. Infect. Dis. Obstet. Gynecol. 7:23–25, 1999.

  20. Detection of hydrogen peroxide-producing Lactobacillus species in the vagina: a comparison of culture and quantitative PCR among HIV-1 seropositive women

    Directory of Open Access Journals (Sweden)

    Balkus Jennifer E

    2012-08-01

    Full Text Available Abstract Background The presence of hydrogen peroxide (H2O2 producing Lactobacillus in the vagina may play a role in controlling genital HIV-1 shedding. Sensitive molecular methods improve our ability to characterize the vaginal microbiota; however, they cannot characterize phenotype. We assessed the concordance of H2O2-producing Lactobacillus detected by culture with quantitative PCR (qPCR detection of Lactobacillus species commonly assumed to be H2O2-producers. Methods Samples were collected as part of a prospective cohort study of HIV-1 seropositive US women. Cervicovaginal lavage specimens were tested for L. crispatus and L. jensenii using 16S rRNA gene qPCR assays. Vaginal swabs were cultured for Lactobacillus and tested for H2O2-production. We calculated a kappa statistic to assess concordance between culture and qPCR. Results Culture and qPCR results were available for 376 visits from 57 women. Lactobacilli were detected by culture at 308 (82% visits, of which 233 of 308 (76% produced H2O2. L. crispatus and/or L. jensenii were detected at 215 (57% visits. Concordance between detection of L. crispatus and/or L. jensenii by qPCR and H2O2-producing Lactobacillus by culture was 75% (kappa = 0.45. Conclusions Among HIV-1 seropositive women, there was a moderate level of concordance between H2O2-producing Lactobacillus detected by culture and the presence of L. crispatus and/or L. jensenii by qPCR. However, one-quarter of samples with growth of H2O2-producing lactobacilli did not have L. crispatus or L. jensenii detected by qPCR. This discordance may be due to the presence of other H2O2-producing Lactobacillus species.

  1. Citología y Análisis Morfométrico de las Células del Epitelio Vaginal Durante el Ciclo Estral en Ovejas de Pelo (Ovis aries) / Citology and Morphometric Analysis of Epithelial Cells from the Vagina of Hair Sheep Ewes (Ovis aries) During their Estrous Cycle

    Scientific Electronic Library Online (English)

    Neftali, Clemente Ovando; Agustín, Orihuela Trujillo; Fernando Iván, Flores Pérez; Virginio, Aguirre Flores.

    2013-09-01

    Full Text Available La citología vaginal puede usarse para caracterizar estados del ciclo reproductivo de la hembra. Sin embargo, no ha sido validada en ovinos de pelo, y ofrece resultados inexactos debido a interpretaciones subjetivas. El objetivo del presente trabajo es tipificar las características morfológicas y mo [...] rfométricas de las células epiteliales de la vagina durante el ciclo estral en ovinos de pelo. Cinco borregas Santa Cruz se sincronizaron con esponjas intravaginales. Desde el día del 1er celo posterior al retiro de la esponja y hasta el siguiente celo, se obtuvieron muestras diarias del epitelio vaginal de cada oveja, y se cuantificó el número de células parabasales, intermedias y superficiales, y se midió la longitud, perímetro y área de citoplasma y núcleo de cada una. Los resultados muestran que las células superficiales incrementan (P Abstract in english Vaginal cytology can be used to characterize stages of the reproductive cycle of the female. However, it has not been validated in hair sheep, and generates inaccurate results due to subjective interpretations. Thus, the purpose of the present work is to typify morphologic and morphometric character [...] istics of the epithelial cells from the vagina during the estrous cycle of hair sheep. Five Saint Croix ewes were synchronized with intravaginal sponges. Day zero of the cycle was considered the day of first estrus after sponge withdrawal. From this day until next estrus, samples from the vaginal epithelium were obtained daily from each ewe. The number of basal, intermediate and superficial cells was quantified, and length, perimeter, and area from cytoplasm and nucleus were obtained. The results show that the number of superficial cells increase (P

  2. Impacts of You Gui Wan on the expression of estrogen receptors and angiogenic factors in OVX?rat vagina: a possible mechanism for the trophic effect of the formula on OVX?induced vaginal atrophy.

    Science.gov (United States)

    Yin, Qiao-Zhi; Lu, Hua; Li, Li-Min; Yie, Shang-Mian; Hu, Xiang; Liu, Zhi-Bin; Zheng, Xiao; Cao, Sheng; Yao, Zou-Ying

    2013-11-01

    The administration of You Gui Wan (YGW) decoction has been observed to improve vaginal atrophy induced by ovariectomy (OVX) in rats. The aim of the current study was to explore the possible mechanisms underlying this effect. Following OVX, 37 Sprague Dawley female rats were randomly divided into three groups which were orally administered with YGW decoction, saline or estrogen for 11 weeks. In parallel with this, 19 normal and 17 rats with sham-surgery were used as controls. The effects of these treatments on estrogen receptors (ER) and various angiogenic factors, including vascular endothelial growth factor (VEGF), vascular endothelial growth factor receptor-1 (VEGFR-1), angiopoietin (Ang)1 and 2 and basic fibroblast growth factor (bFGF) in the vagina were compared using immunohistochemistry or quantitative polymerase chain reaction (qPCR). OVX was found to induce significant vaginal atrophy and decrease the expression of ER and various angiogenic factors when compared with the normal and sham-surgery animals (all Pvaginal atrophic process. The hormonal replacement and YGW treatment recovered the protein expression of ER-? and -?, VEGF and VEGFR-1 and the mRNA levels of ER-?, VEGF, VEGFR-1, Ang1 and 2, and bFGF when compared with OVX-rats with saline, normal and sham-surgery treatments (all Pvaginal atrophy may be the upregulated expression of ER and various angiogenic factors in the vaginal tissue. PMID:24009028

  3. MRI of the uterus, uterine cervix, and vagina: diagnostic performance of dynamic contrast-enhanced fast multiplanar gradient-echo imaging in comparison with fast spin-echo T2-weighted pulse imaging

    International Nuclear Information System (INIS)

    The aim of this study was to compare the diagnostic performance of contrast-enhanced fast multiplanar gradient-echo (GRE) and T2-weighted fast spin-echo (FSE) image sets in the assessment of uterus, cervix, and vagina. Fast (up to 20 contiguous sections in 23 s) multiplanar GRE and FSE images of 45 patients referred for imaging of the female pelvis were evaluated retrospectively with regard to overall image quality and the ability to detect normal anatomic structures, as well as lesion conspicuity. Results were compared with histologic findings (n = 29) or clinical follow-up. Furthermore, a quantitative assessment of contrast-to-noise ratios among normal uterine and cervical structures as well as uterine lesions was performed for both sequences. On GRE images, uterine and cervical differentiation was best seen on the image sets acquired 15 and 60 s following contrast enhancement and results were significantly better compared with delayed images (p 2 test, the difference in diagnostic performance between FSE and GRE revealed no significant difference, whereas the combination of both techniques performed better than FSE imaging alone (p < 0.05). The presented data suggest that dynamic contrast-enhanced GRE imaging should be part of an MR examination of the female pelvis. Combined GRE and FSE imaging provide an excellent sensitivity in the assessment of uterine and vaginal pathologies. (orig.) (orig.)

  4. Congenital malformations of uterus and vagina

    International Nuclear Information System (INIS)

    The radiographic findings according to the classification of Buttram and Gibbons are described for HSG, ultrasound and MRI. The advantages and limitations of each method are discussed, and finally an algorithm for imaging is recommended. (orig.)

  5. Prevalência de cândida na flora vaginal de mulheres atendidas num serviço de planejamento familiar Prevalence of candida in the vagina of women attended at a family planning service

    Directory of Open Access Journals (Sweden)

    Antônio Aleixo Neto

    1999-01-01

    Full Text Available RESUMO Objetivo: avaliar a prevalência de Candida sp. e a distribuição de suas espécies na flora vaginal de mulheres numa clínica de planejamento familiar. Método: estudo transversal no qual se avaliaram prospectivamente 72 mulheres não-grávidas, com ou sem queixas específicas, sendo coletadas amostras de secreção vaginal para cultura de leveduras, efetuada a medição do pH vaginal e anotados dados de achados do exame ginecológico. Resultados: leveduras pertencentes ao gênero Candida foram encontradas em 18 casos (25%. A C. albicans foi a espécie mais prevalente (77,8% e conseqüentemente 22,2% foram não-albicans. Entre as não-albicans a espécie mais prevalente foi a C. glabrata (16,7% seguida pela C. parapsilosis (5,6%. Prurido e ardor foram os únicos sintomas relacionados significativamente com a presença de cândida. Foi observado que a C. glabrata, ao contrário da C. albicans, não causa corrimento clinicamente verificável ao exame ginecológico. Não foram verificadas associações de alguns fatores predisponentes (idade, escolaridade e uso de contraceptivos com a presença ou não de cândida. Conclusões: nossos resultados sugerem: a uma alta prevalência de Candida sp. entre as mulheres (25%; b que as espécies não-albicans desempenham um papel importante no meio vaginal; c que prurido e ardor são os sintomas mais comuns na presença de cândida e d que a C. glabrata não costuma causar corrimento vaginal ao exame ginecológico. Finalmente, é importante observar que nossos resultados são consistentes com o que a literatura internacional tem mostrado nos últimos anos.SUMMARY Purpose: to estimate the prevalence of Candida sp. and the distribution of its species in the vagina of women attended at a family planning Service. Methods: a cross-sectional study evaluating prospectively 72 nonpregnant women, with or without specific complaints. Samples were checked for the presence of yeast and vaginal pH. Data obtained by gynecologic examination were also recorded. Results: yeast belonging to the genus Candida was isolated from 18 (25% patients. The most prevalent species was C. albicans (77,8% and therefore, 22.2% were non-albicans species. The most prevalent among the non-albicans species was C. glabrata (16.7% followed by C. parapsilosis (5.6%. The symptoms most directly associated with Candida were itching and burning. Different from the symptoms directly associated with C. albicans infection, we observed that C. glabrata does not cause vaginal discharge. There was no positive association between predisponent factors such as age, education and contraceptive method used and the presence or absence of Candida. Conclusions: our results suggest: (i that there is a high prevalence of Candida species among women; (ii that non-albicans species play an important role in the vaginal medium; (iii that itching and burning are the most common symptoms in women with Candida, and (iv C. glabrata usually does not cause vaginal discharge. Finally, it is important to emphasize that our results are consistent with the present worldwide findings.

  6. Caracterización de la microbiota levaduriforme residente en la vagina de perras en diferentes fases del ciclo estral Characterization of vaginal microbiotic yeasts of bitches in distinct stages of the oestrous cycle

    Directory of Open Access Journals (Sweden)

    M B Cleff

    2007-01-01

    Full Text Available Hongos levaduriformes son aislados frecuentemente de los animales domésticos y silvestres, siendo algunos comensales del tegumento y mucosas. Las levaduras son frecuentes en la mucosa vaginal de las mujeres, pero en perras son escasos los estudios referentes a la microbiota fúngica vaginal, sin conocerse su relación con el ciclo reproductivo. En este estudio se buscó aislar e identificar levaduras de la microbiota vaginal de perras, y establecer si hay alteración de la microbiota levaduriforme en las fases del ciclo reproductivo. Se analizaron 75 muestras de la vagina de 75 perras de los caniles particulares (Grupo I y 224 muestras de 14 perras experimentales (Grupo II. El ciclo estral fue determinado por citología vaginal y se registraron observaciones clínicas como sangrado, edema y pliegues de vulva. Las muestras fueron sometidas a examen directo y cultivos en Agar-Sabouraud dextrosa con cloranfenicol, a 37 ºC por 10 días. Las levaduras fueron clasificadas por macro y micromorfología, pruebas bioquímicas, tubo germinativo y microcultivo. De las 75 muestras del grupo I, el aislamiento fue 33,3% (n = 25; las muestras fueron obtenidas en las fases de proestro 56,3%, estro 16,7%, diestro 66,7% y anestro 20,5%, respectivamente. De las 224 muestras del grupo II se aislaron levaduras en 147 (65,6%: en proestro 61,9%, estro 71,9%, diestro 82,7% y anestro 57,1%, respectivamente. Las levaduras fueron identificadas como Candida spp, Malassezia pachydermatis y Rhodoturola spp. Los resultados sugieren que estas levaduras forman parte de la microbiota vaginal de perras sanas y sus frecuencias se alteran en las fases del ciclo reproductivo.Yeasts are commensal organisms frequently isolated from the skin and mucous membranes of domestic and wild mammals. Although yeasts are frequently isolated from women’s vaginal mucus, similar studies in canine are rare, therefore their behaviour during the canine oestrous cycle is unknown. The purpose of this study was to isolate yeasts from the vaginal microbiota of bitches and to evaluate their behaviour in different stages of the oestrous cycle. We examined 75 samples of mucus from the vaginal cavity of 75 domestic bitches and 224 samples from 14 experimental bitches. The stages of the oestrous cycle were characterized through vaginal cytology and clinical observation of bleeding, vulvar oedema and pucker. Samples were examined visually, and also cultured in Sabouraud dextrose agar with chloranphenicol, at 37 ºC for 10 days. The yeasts were classified according to their macro and micro morphology, biochemical tests, germination tube and micro culture. Yeasts were isolated from 25 (33.3% samples from domestic females. Among the samples collected during proestrous, oestrous, diestrous and anestrous, 56.3% 16.7% 66.7% and 20.5% were positive, respectively. Yeasts were isolated from 147 (65.6% samples from experimental bitches. Among the samples collected during proestrous, oestrous, diestrous and anestrous, positive samples represented 61.9%, 71.9%, 82.7%, and 57.1%, respectively. The identified species were Candida spp, M. pachydermatis and Rhodotorula spp, which are commonly present in the vaginal mucus microbiota of healthy bitches and their frequency changes with the different stages of the oestrous cycle.

  7. Caracterización de la microbiota levaduriforme residente en la vagina de perras en diferentes fases del ciclo estral / Characterization of vaginal microbiotic yeasts of bitches in distinct stages of the oestrous cycle

    Scientific Electronic Library Online (English)

    M B, Cleff; M O, Xavier; A A, Martins; R, Santin; M C A, Meireles.

    Full Text Available Hongos levaduriformes son aislados frecuentemente de los animales domésticos y silvestres, siendo algunos comensales del tegumento y mucosas. Las levaduras son frecuentes en la mucosa vaginal de las mujeres, pero en perras son escasos los estudios referentes a la microbiota fúngica vaginal, sin cono [...] cerse su relación con el ciclo reproductivo. En este estudio se buscó aislar e identificar levaduras de la microbiota vaginal de perras, y establecer si hay alteración de la microbiota levaduriforme en las fases del ciclo reproductivo. Se analizaron 75 muestras de la vagina de 75 perras de los caniles particulares (Grupo I) y 224 muestras de 14 perras experimentales (Grupo II). El ciclo estral fue determinado por citología vaginal y se registraron observaciones clínicas como sangrado, edema y pliegues de vulva. Las muestras fueron sometidas a examen directo y cultivos en Agar-Sabouraud dextrosa con cloranfenicol, a 37 ºC por 10 días. Las levaduras fueron clasificadas por macro y micromorfología, pruebas bioquímicas, tubo germinativo y microcultivo. De las 75 muestras del grupo I, el aislamiento fue 33,3% (n = 25); las muestras fueron obtenidas en las fases de proestro 56,3%, estro 16,7%, diestro 66,7% y anestro 20,5%, respectivamente. De las 224 muestras del grupo II se aislaron levaduras en 147 (65,6%): en proestro 61,9%, estro 71,9%, diestro 82,7% y anestro 57,1%, respectivamente. Las levaduras fueron identificadas como Candida spp, Malassezia pachydermatis y Rhodoturola spp. Los resultados sugieren que estas levaduras forman parte de la microbiota vaginal de perras sanas y sus frecuencias se alteran en las fases del ciclo reproductivo. Abstract in english Yeasts are commensal organisms frequently isolated from the skin and mucous membranes of domestic and wild mammals. Although yeasts are frequently isolated from women’s vaginal mucus, similar studies in canine are rare, therefore their behaviour during the canine oestrous cycle is unknown. The purpo [...] se of this study was to isolate yeasts from the vaginal microbiota of bitches and to evaluate their behaviour in different stages of the oestrous cycle. We examined 75 samples of mucus from the vaginal cavity of 75 domestic bitches and 224 samples from 14 experimental bitches. The stages of the oestrous cycle were characterized through vaginal cytology and clinical observation of bleeding, vulvar oedema and pucker. Samples were examined visually, and also cultured in Sabouraud dextrose agar with chloranphenicol, at 37 ºC for 10 days. The yeasts were classified according to their macro and micro morphology, biochemical tests, germination tube and micro culture. Yeasts were isolated from 25 (33.3%) samples from domestic females. Among the samples collected during proestrous, oestrous, diestrous and anestrous, 56.3% 16.7% 66.7% and 20.5% were positive, respectively. Yeasts were isolated from 147 (65.6%) samples from experimental bitches. Among the samples collected during proestrous, oestrous, diestrous and anestrous, positive samples represented 61.9%, 71.9%, 82.7%, and 57.1%, respectively. The identified species were Candida spp, M. pachydermatis and Rhodotorula spp, which are commonly present in the vaginal mucus microbiota of healthy bitches and their frequency changes with the different stages of the oestrous cycle.

  8. Biofilm formation among Candida albicans isolated from vagina

    OpenAIRE

    D C Thamke; H A Tayade; Surekha Tayade; Bankar, N. J.; Rathod, N. G.

    2014-01-01

    Purpose: Study was conducted in a rural tertiary care hospital with a purpose to demonstrate the biofilm forming abilities of C. albicans isolated from cases of vulvovaginal candidiasis and asymptomatic carriers.Material and Methods: C. albicans was isolated and identified by standard laboratory techniques. Biofilm formation in vitro was tested using the 96 well microtitre plate method with crystal violet staining.Results: Overall rate of Candida isolation in study subjects was 40%. Candida i...

  9. Pregnancy Complications: Bleeding and Spotting from the Vagina

    Science.gov (United States)

    ... Chapters Frequently asked questions Contact us Tools & Resources Born Too Soon Global Map Premature birth report card Careers Archives Pregnancy ... Chapters Frequently asked questions Contact us Tools & Resources Born Too Soon Global Map Premature birth report card Careers Archives Health ...

  10. Radiotherapeutic management of carcinomas of the vagina and vulva

    International Nuclear Information System (INIS)

    Purpose: To review important basic information regarding vaginal and vulvar carcinomas, including etiology, epidemiology, anatomy, pathology, spread patterns, presentation and work-up and staging. In addition, treatment concepts strategies, and radiotherapeutic techniques will be reviewed and discussed. Discussion: Vaginal carcinoma is rare, making up only 1-2% of gynecologic malignancies. However, the predominant role of radiotherapy (RT) is its management results in a significant number of patients referred to radiation oncology. Treatment and outcomes vary substantially according to stage. Important issues for consideration include the respective roles of external beam RT, brachytherapy, and surgery, intracavitary vs. interstitial brachytherapy, dose rate considerations, combined modality therapy, and management of non-squamous cell histologies. Vulvar carcinoma is similarly uncommon, comprising only 3-5% of gynecologic malignancies. Radiotherapy has a number of established roles in the management of this disease including adjuvant therapy, as part of combined modality treatment for advanced disease, salvage therapy, palliative treatment, and less often, as primary management. These issues will be discussed along with technical factors important in radiotherapeutic management. Finally, relevant literature will be reviewed with an emphasis of completed Gynecologic Oncology Group Trials

  11. Late effects of ionizing radiations on vulva, vagina and uterus

    International Nuclear Information System (INIS)

    Reporting and scoring complications after radiotherapy of gynaecological cancers is difficult because of the variety of treatment techniques involved. Use of an international classification is necessary to compare results obtained in series of patients treated in different institutions. An international group of experts designed in the early nineties the so-called French-Italian glossary. This classification of late effects is now completed with the new LENT SOMA scales. This paper contains details of these late changes, including their pathophysiology, clinical syndromes, potential treatment, and prevention. (authors)

  12. Malla de polipropileno multifilamento con autofijación de silicona exteriorizada a vagina / Multifilament polypropylene mesh with exteriorization of the silicone anchorage to the vagina

    Scientific Electronic Library Online (English)

    Vicente, Solà Dalenz; Jack, Pardo Schanz; Paolo, Ricci Arriola; Enrique, Guiloff Fische.

    2007-11-01

    Full Text Available Objetivo: Describir un caso de falla de en una cirugía de cinta suburetral para corrección de la incontinencia de orina de esfuerzo con sistema Safyre VS (vaginal-suprapubic approach) multifilamento, a los 34 meses de buena evolución. Método: Descripción del caso y su resolución. Resultado: Se prese [...] ntó con descenso del sistema de sujeción lateral y erosión de la mucosa vaginal con exposición de la cinta e infección. Se retiró con gran facilidad el sistema de anclaje de silicona que se encontraba suelto y se colocó una nueva cinta suburetral con sistema TVT-O, recuperando la continencia antes lograda. Conclusiones: La malla sintéticas de los sistemas de corrección con cinta suburetral para la incontinencia de orina de esfuerzo, deben ser de polipropileno, macroporo y monofilamento. Estas características permiten una mejor biointegración, reduciendo teóricamente el número de complicaciones (erosión de pared vaginal, exposición y sobreinfección). Respecto a la falla del sistema de sujeción de silicona, ya que no se han informado otros casos en los estudios de seguimiento entre 12 y 36 meses (media 14 y 18 meses), sólo los estudios que contemplen seguimientos a largo plazo permitirán decir si se trata de un caso aislado o aparecerán otros. Abstract in english Objectives: To describe the failure of one case of suburethral tape for the correction of the stress urinary incontinence with the multifilament Sapphire VS (vaginal-suprapubic approach) system after 34 months of good outcome. Methods: Description of the case and its resolution. Results: The patient [...] presented with a descent of the lateral fixation and erosion of the vaginal mucosa with exposure of the mesh and infection. The silicone fixation system, which was loose, was retrieved very easily and a new suburethral mesh with the system TVT-O was inserted; the patient recovered continence as before. Conclusions: Synthetic mesh in the suburethral tape systems for stress urinary incontinence correction should be polypropylene, macropore and monofilament. These characteristics enable better bio integration, theoretically reducing the number of complications (vaginal wall erosion, exposition and over infection). In relation with the failure of the silicone fixation system, no other casers have been reported in follow-up studies between 12 and 36 months (mean follow-up 14 and 18 months), so hat studies with long-term follow-up will be able to determine if this is an isolated case or there will be others.

  13. Primary invasive cancer of the vagina: outcome and complications of therapy

    International Nuclear Information System (INIS)

    The aim of the present study was to review the characteristics of cases of vaginal cancer, results of treatment and complications occurring at Westmead Hospital over the period 1979-96. International Federation of Gynaecology and Obstetrics (FIGO) staging and Eastern Cooperative Oncology Group (ECOG) status had been recorded prospectively, while other information was obtained retrospectively, including complications using the Franco-Italian Glossary. There were 37 eligible patients, 34 of whom were treated radically. Five-year survival for stage I was 90%, for stage 11 it was 50%, and for stage III it was 40%. There was only one stage-V patient. The majority of patients who relapsed did so locally (63%). Using the Franco-Italian Glossary 10.8% of patients had, at worst, G0 toxicity, 21.6% had G1 toxicity, 29.7% had G2 toxicity, 37.8% had G3 toxicity, and no patients had G4 toxicity. Seven patients (18.9%) had a laparotomy for a complication of therapy. Excluding the three palliative patients and controlling for disease stage, it was found that there was a trend to improved survival in patients who had brachytherapy and those who suffered worse complications. While results for treatment of early stage vaginal cancer appear good, new techniques, particularly those that improve local control, are required for higher stage disease. Copyright (1999) Blackwell Science Pty Ltd

  14. The influence of radium therapie on the yeast contamination of the vagina

    International Nuclear Information System (INIS)

    Before the beginning of radium therapy a vaginal yeast contamination of 9,7% was found of 113 patients with various genital carcinomas. However, the incidence of vaginal yeast contamination increased suddenly to 30,9% under the contac irradiation therapy with radium. The radiation effect of radium is not sufficient for a 'selfsterilisation' of the radium-carrier in the case of yeast contamination. Therefore, a chemic desinfection of the radium-carriers is principly necessary. The significance is discussed and the recommendation is made that routine mycological supervision be carried out on all patients with gynaecological carcinomas and appropriate antimycotic therapy initiated where necessary. (orig.)

  15. "The Vagina is a Very Tricky Little Thing Down There": Cervical Health Literacy among Incarcerated Women.

    Science.gov (United States)

    Ramaswamy, Megha; Kelly, Patricia J

    2015-11-01

    The objective of this study was to understand factors associated with women's ability to engage in cervical cancer prevention and follow-up care given ongoing criminal justice involvement. We conducted four focus groups with 45 incarcerated women to assess barriers to cervical health promotion, and used a grounded theory method to analyze data. We administered the Short Test of Functional Health Literacy in Adults to assess general health literacy as a standalone factor related to cervical health promotion. Ninety-one percent of participants had adequate health literacy scores. However, we found that the women had varying levels of cervical health literacy, which we operationalized as knowledge, beliefs, and self-efficacy related to cervical health promotion. Practitioners should establish broader interventions to empower women with criminal justice histories to take control of their own cervical health and focus on communicating updated recommendations to improve cervical health understanding, beliefs, and practices among high-risk women. PMID:26548678

  16. Impact of Pregnancy and Vaginal Delivery on the Passive and Active Mechanics of the Rat Vagina

    OpenAIRE

    Feola, Andrew; Moalli, Pamela; Alperin, Marianna; Duerr, Robbie; Gandley, Robin E.; Bramowitch, Steven

    2010-01-01

    Remodeling of vaginal extracellular matrix and smooth muscle likely plays a critical role in reducing the risk of maternal injury during vaginal delivery by altering the mechanical properties to increase distension and reduce stress. Long-Evans rats were divided into five groups to examine the passive mechanical and active contractile properties throughout pregnancy and postpartum: virgin (n = 17), mid-pregnant (Day 14–16, n = 12), late-pregnant (Day 20–22, n = 14), immediate postpartum (0–2 ...

  17. Kadar Estradiol dan Progesteron Serum, Tampilan Vulva dan Sitologi Apus Vagina Kambing Bligon Selama Siklus Birahi

    OpenAIRE

    Irkham Widiyono; Prabowo Purwono Putro; Sarmin -; Pudji Astuti; Claude Mona Airin

    2012-01-01

    A study was carried out to determine the serum estradiol and progesterone concentration, vulvaappearance, and vaginal cytology during estrous cycle in bligon goat. Four female non pregnant bligongoats (Indonesian indigenous) were used in this research. They were clinically healthy and showed normalestrous cycle. Estrous state was examined by using biological method. When the animals showed acceptanceto be mounted by a buck, they were confirmed as the first day of estrous cycle (estrous phase)...

  18. Kadar Estradiol dan Progesteron Serum, Tampilan Vulva dan Sitologi Apus Vagina Kambing Bligon Selama Siklus Birahi

    Directory of Open Access Journals (Sweden)

    Irkham Widiyono

    2012-11-01

    Full Text Available A study was carried out to determine the serum estradiol and progesterone concentration, vulvaappearance, and vaginal cytology during estrous cycle in bligon goat. Four female non pregnant bligongoats (Indonesian indigenous were used in this research. They were clinically healthy and showed normalestrous cycle. Estrous state was examined by using biological method. When the animals showed acceptanceto be mounted by a buck, they were confirmed as the first day of estrous cycle (estrous phase. Collectionof blood sample, preparation of vaginal smears, and measurement of some physical genital parameterswere conducted by standard veterinary clinical methods at day 11, day between 3-5, day between 6-16, andday between 17-19 of estrous cycle. Enzyme linked immunosorbent assay (ELISA was used to determineserum progesterone and estradiol concentrations. Mean difference of each parameter was analyzed byanalyses of variance (Anova, followed by Tuckey HSD. The serum estradiol concentration ranged between211.25-247.77 pg/ml. Peak of the estradiol was occurred at the first day of estrous phase, namely 247.77pg/ml and to decrease at day 3-16. The serum progesterone concentration was at the level of 0.21-0.70 ng/ml and showed a significant increase at day 6-16 (p<0.05. The specific physical genital changes (swellingvulva, reddish mucous membrane of vulva, and excretion of viscous transparent vaginal discharge wereidentified as the animals were at the estrous phase. Composition of exfoliative vaginal cytology did notshow any specific and consistent changes throughout the estrous cycle. Superficial and intermediate cellswere very dominant (>60% during estrous cycle. In conclusion, serum estradiol, progesterone, the vulvaappearance combined with sexual receptivity could be a good estrous predictor for female cycling bligongoat.

  19. Unusual foreign body insertion in rectum and vagina in schizophrenic patient

    Directory of Open Access Journals (Sweden)

    Raheel Mushtaq

    2014-02-01

    Full Text Available Insertion of foreign body in to the body is rare in medical literature. Here we report a case of 21 year old female who presented to emergency with acute abdomen and on detailed evaluation turned out to be schizophrenia. Our patient had history of insertion of ball pen in rectum following command hallucination. The foreign body was later removed through laparotomy. The cause of insertion of foreign body are multiple from command hallucination, suicidal attempt, erotism to somatic delusions. Thus the clinician should always be vigilant while dealing with psychiatric patients as sometimes impacted foreign body can present as acute emergency. [Int J Res Med Sci 2014; 2(1.000: 367-369

  20. Radiotherapy for carcinoma of the vagina. Immunocytochemical and cytofluorometric analysis of prognostic factors

    Energy Technology Data Exchange (ETDEWEB)

    Blecharz, P. [Maria Sklodowska-Curie Memorial Institute, Krakow (Poland). Dept. of Gynecological Oncology; Reinfuss, M.; Jakubowicz, J. [Maria Sklodowska-Curie Memorial Institute, Krakow (Poland). Dept. of Radiation Oncology; Rys, J. [Maria Sklodowska-Curie Memorial Institute, Krakow (Poland). Dept. of Tumor Pathology Oncology; Skotnicki, P.; Wysocki, W. [Maria Sklodowska-Curie Memorial Institute, Krakow (Poland). Dept. of Oncological Surgery

    2013-05-15

    Background and purpose: The aim of this study was to assess the potential prognostic factors in patients with primary invasive vaginal carcinoma (PIVC) treated with radical irradiation. Patients and methods: The analysis was performed on 77 patients with PIVC treated between 1985 and 2005 in the Maria Sklodowska-Curie Memorial Institute of Oncology, Cancer Center in Krakow. A total of 36 patients (46.8 %) survived 5 years with no evidence of disease (NED). The following groups of factors were assessed for potential prognostic value: population-based (age), clinical (Karnofsky Performance Score [KPS], hemoglobin level, primary location of the vaginal lesion, macroscopic type, length of the involved vaginal wall, FIGO stage), microscopic (microscopic type, grade, mitotic index, presence of atypical mitoses, lymphatic vessels invasion, lymphocytes/plasmocytes infiltration, focal necrosis, VAIN-3), immunohistochemical (protein p53 expression, MIB-1 index), cytofluorometric (ploidity, index DI, S-phase fraction, proliferation index SG2M) factors. Results: Significantly better 5-year NED was observed in patients: < 60 years, KPS {<=} 80, FIGO stage I and II, grade G1-2, MIB-1 index < 70, S-phase fraction < 10, and proliferation index < 25. Independent factors for better prognosis in the multivariate Cox analysis were age < 60 years, FIGO stage I or II, and MIB-1 index < 70. Conclusion: Independent prognostic factors in the radically irradiated PIVC patients were as follows: age, FIGO stage, MIB-1 index. (orig.)

  1. Laparoscopic management of fallopian tube prolapse masquerading as adenocarcinoma of the vagina in a hysterectomized woman

    Directory of Open Access Journals (Sweden)

    Kucuk Mustafa

    2002-01-01

    Full Text Available Abstract Background Fallopian tube prolapse as a complication of abdominal hysterectomy is a rare occurrence. A case with fallopian tube prolapse was managed by a combined vaginal and laparoscopic approach and description of the operative technique is presented. Case presentation A 39-year-old woman with vaginal prolapse of the fallopian tube after total abdominal hysterectomy presented with an incorrect diagnosis of adenocarcinoma of the vaginal apex. The prolapsed tube and cystic ovary were removed by vaginal and laparoscopic approach. The postoperative course went well. Conclusions Early or late fallopian tube prolapse can occur after total abdominal hysterectomy and vaginal hysterectomy. Symptoms consist of persistent blood loss or leukorrhea, dyspareunia and chronic pelvic pain. Vaginal removal of prolapsed tube with laparoscopic surgery may be a suitable treatment. The abdominal or vaginal approach used in surgical correction of prolapsed tubes must be decided in each case according to the patient's individual characteristics.

  2. Fine structure of the male reproductive ducts, vagina and seminal receptacle of Cyathocephalus truncatus (Cestoda: Spathebothriidea).

    Czech Academy of Sciences Publication Activity Database

    Poddubnaya, L. G.; Mackiewicz, J. S.; Bru?anská, Magdaléna; dezfuli, B. S.

    2005-01-01

    Ro?. 52, ?. 3 (2005), s. 241-250. ISSN 0015-5683 R&D Projects: GA ?R GA206/03/1317 Grant ostatní: Russian Foundation of Fundamental Research(RU) 05-0448250 Institutional research plan: CEZ:AV0Z60220518 Keywords : ultrastructure * reproductive organs * Cestoda Subject RIV: EA - Cell Biology Impact factor: 1.138, year: 2005

  3. Isolated epithelioid trophoblastic tumor of the vagina: a case report and review of the literature

    Directory of Open Access Journals (Sweden)

    Zhao J

    2013-10-01

    Full Text Available Jing Zhao,1 Yang Xiang,1 Dachun Zhao,2 Tong Ren,1 Fengzhi Feng,1 Xirun Wan1 1Department of Obstetrics and Gynecology, 2Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China Abstract: An epithelioid trophoblastic tumor (ETT is a rare trophoblastic tumor originating from chorionic-type intermediate trophoblasts. Vaginal involvement in ETT in the form of isolated lesions has not been previously reported. A 43-year-old woman presented with vaginal wall cysts and was diagnosed with ETT by pathological examination after cystectomy. No clinical evidence of uterine involvement was found at diagnosis or during follow-up. The patient was treated with chemotherapy and surgery after the first recurrence and underwent follow-up for 8 months. The serum human chorionic gonadotropin titer remained at undetectable levels. Keywords: ETT, isolated lesions, vaginal involvement

  4. Sheila Jeffreys: The Industrial Vagina. The Political Economy of the Global Sex Trade. London: Routledge 2008.

    Directory of Open Access Journals (Sweden)

    Susanne Hofmann

    2010-03-01

    Full Text Available Sheila Jeffreys analysiert die Prozesse, die zu einer Industrialisierung und Globalisierung von Prostitution im späten 20. und 21. Jahrhundert geführt haben. Hauptverantwortlich für die gegenwärtige Diskursverschiebung um Prostitution ist für Jeffreys zum einen die sexuelle Revolution der 1970er Jahre und zum anderen die massive Finanzierung von Unterstützer/-innen der Sexarbeiterinnen zur HIV-Prävention in den 1980ern. Jeffreys legt wie in früheren Arbeiten ihre radikal-feministische Position dar und fordert eine Abschaffung der Prostitution. In ihrer Abrechnung mit dem liberalen feministischen Diskurs, für den eine Unterstützung von Sexarbeiterinnen prioritär ist, ignoriert sie die Widersprüchlichkeiten und Komplexitäten der gelebten Realitäten. An vielen Stellen ihres Buches bekräftigt Jeffreys stereotypische Männlichkeitsvorstellungen, was durch einen Blick über den Tellerrand des ihr vertrauten wissenschaftlichen Bezugsrahmens hätte vermieden werden können.Sheila Jeffreys analyzes the processes that led to the industrialization and globalization of prostitution in the late 20th and 21th centuries. Jeffreys considers those primary factors responsible for the current shift in discourse on prostitution, which can be attributed to the sexual revolution of the 1970s on the one hand, and to massive financing of HIV prevention in the 1980s by sex worker supporters on the other. As in earlier studies, Jeffreys presents readers with her radical-feminist position and demands prostitution be abolished. In her confrontation with liberal-feminist discourse, in which the support of sex workers takes priority, she ignores the inconsistencies and complexities of real lived experience. At many points throughout her book, Jeffreys affirms stereotypical male conceptions, which could have been avoided had she looked beyond the theoretical frame of reference that makes up her comfort zone.

  5. Sodium Tetradecyl Sulphate Direct Intralesional Sclerotherapy of Venous Malformations of the Vulva and Vagina: Report of Five Cases

    International Nuclear Information System (INIS)

    We report five cases of female patients affected by symptomatic focal external genital venous malformations treated with percutaneous direct intralesional injection of sodium tetradecyl sulphate (STS). All patients were referred because of discomfort and pain when sexual intercourse was attempted. Direct sclerotherapy with 3% STS was performed on a day-hospital basis with the patient under local anesthesia. Complete resolution of the symptoms was achieved in all cases. No major adverse effects were reported. Direct intralesional sclerotherapy with STS may be considered a safe and effective method for the treatment of female external genital malformation without the necessity of general anesthesia for pain control.

  6. Canid herpesvirus 1 (CHV-1)-related disease in older puppies and CHV-1 shedding in the vagina of adult pregnant dogs.

    Science.gov (United States)

    Kapil, Sanjay

    2015-11-01

    A large breeding kennel of Bulldogs (n = 57) experienced several Canid herpesvirus 1 (CHV-1)-related diseases in older puppies (9 weeks of age) in Arkansas. CHV-1 has been repeatedly confirmed in the kennel in several animals for 3 years (January 2012-February 2015) using various virology tests. I was able to detect a partial sequence of CHV DNA (~120 bp) in archived formalin-fixed, paraffin-embedded tissue blocks after 3 years of storage. CHV-1 is persistently circulating in this kennel in spite of high serum antibody titers in the adult dogs. The dogs were negative for canine brucellosis antibodies based on Brucella canis rapid card test. PMID:26450840

  7. Carcinoma epidermoide no queratinizante de células grandes y pequeñas en vagina / Large and small cells non-keratinizing epidermoid vaginal carcinoma

    Scientific Electronic Library Online (English)

    Ofelia, Masó Anaya; María Elena, Morales Larramendi; Dolores, Díaz Pérez; Esperanza, Dager Dager; Gloria Adelaida, Bolaños Diego.

    2012-03-01

    Full Text Available Se presentan 5 casos clínicos de pacientes atendidas en la consulta de patología de cuello del Hospital Provincial Ginecoobstétrico "Mariana Grajales Coello" de Santiago de Cuba por presentar sangrado vaginal, dolor en bajo vientre, leucorrea y lesiones vaginales. El estudio anatomopatológico confir [...] mó el diagnóstico de carcinoma de células escamosas o epidermoide. Abstract in english Five case reports of patients who were assisted at the cervix Pathology Department from "Mariana Grajales Coello" Provincial Gynecological Obstetrical Hospital in Santiago de Cuba due to vaginal bleeding, low abdominal pain, leukorrhea and vaginal injuries are presented. The pathological study confi [...] rmed the diagnosis of squamous or epidermoid cells carcinoma.

  8. SU-E-T-579: Impact of Cylinder Size in High-Dose Rate Brachytherapy (HDRBT) for Primary Cancer in the Vagina

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, H; Gopalakrishnan, M; Lee, P; Sathiaseelan, V [Department of Radiation Oncology, Northwestern Memorial Hospital, Chicago, IL (United States)

    2014-06-01

    Purpose: To evaluate the dosimetric impact of cylinder size in high dose rate Brachytherapy for primary vaginal cancers. Methods: Patients treated with HDR vaginal vault radiation in a list of cylinders ranging from 2.5 to 4 cm in diameter at 0.5 cm increment were analyzed. All patients’ doses were prescribed at the 0.5 cm from the vaginal surface with different treatment lengths. A series of reference points were created to optimize the dose distribution. The fraction dose was 5.5 Gy, the treatment was repeated for 4 times in two weeks. A cylinder volume was contoured in each case according to the prescribed treatment length, and then expanded to 5 mm to get a volume Cylinder-5mm-exp. A volume of PTV-Eval was obtained by subtracting the cylinder volume from the Cylinder-5mm-exp. The shell volume, PTV-Eval serves as the target volume for dosimetric evaluation. Results: DVH curves and average doses of PTV-Eval were obtained. Our results indicated that the DVH curves shifted toward higher dose side when larger cylinder was used instead of smaller ones. When 3.0 cm cylinder was used instead of 2.5 cm, for 3.0 cm treatment length, the average dose only increased 1%, from 790 to 799 cGy. However, the average doses for 3.5 and 4 cm cylinders respectively are 932 and 1137 cGy at the same treatment length. For 5.0 cm treatment length, the average dose is 741 cGy for 2.5 cm cylinder, and 859 cGy for 3 cm cylinder. Conclusion: Our data analysis suggests that for the vaginal intracavitary HDRBT, the average dose is at least 35% larger than the prescribed dose in the studied cases; the size of the cylinder will impact the dose delivered to the target volume. The cylinder with bigger diameter tends to deliver larger average dose to the PTV-Eval.

  9. Role of HOXA7 to HOXA13 and PBX1 genes in various forms of MRKH syndrome (congenital absence of uterus and vagina

    Directory of Open Access Journals (Sweden)

    Pellerin Isabelle

    2006-03-01

    Full Text Available Abstract The Mayer-Rokitansky-Küster-Hauser (MRKH syndrome refers to the congenital absence or severe hypoplasia of the female genital tract, often described as uterovaginal aplasia which is the prime feature of the syndrome. It is the second cause of primary amenorrhea after gonadal dysgenesis and occurs in ~1 in 4500 women. Aetiology of this syndrome remains poorly understood. Frequent association of other malformations with the MRKH syndrome, involving kidneys, skeleton and ears, suggests the involvement of major developmental genes such as those of the HOX family. Indeed mammalian HOX genes are well known for their crucial role during embryogenesis, particularly in axial skeleton, hindbrain and limb development. More recently, their involvement in organogenesis has been demonstrated notably during urogenital differentiation. Although null mutations of HOX genes in animal models do not lead to MRKH-like phenotypes, dominant mutations in their coding sequences or aberrant expression due to mutated regulatory regions could well account for it. Sequence analysis of coding regions of HOX candidate genes and of PBX1, a likely HOX cofactor during Müllerian duct differentiation and kidney morphogenesis, did not reveal any mutation in patients showing various forms of MRKH syndrome. This tends to show that HOX genes are not involved in MRKH syndrome. However it does not exclude that other mechanisms leading to HOX dysfunction may account for the syndrome.

  10. SU-E-T-579: Impact of Cylinder Size in High-Dose Rate Brachytherapy (HDRBT) for Primary Cancer in the Vagina

    International Nuclear Information System (INIS)

    Purpose: To evaluate the dosimetric impact of cylinder size in high dose rate Brachytherapy for primary vaginal cancers. Methods: Patients treated with HDR vaginal vault radiation in a list of cylinders ranging from 2.5 to 4 cm in diameter at 0.5 cm increment were analyzed. All patients’ doses were prescribed at the 0.5 cm from the vaginal surface with different treatment lengths. A series of reference points were created to optimize the dose distribution. The fraction dose was 5.5 Gy, the treatment was repeated for 4 times in two weeks. A cylinder volume was contoured in each case according to the prescribed treatment length, and then expanded to 5 mm to get a volume Cylinder-5mm-exp. A volume of PTV-Eval was obtained by subtracting the cylinder volume from the Cylinder-5mm-exp. The shell volume, PTV-Eval serves as the target volume for dosimetric evaluation. Results: DVH curves and average doses of PTV-Eval were obtained. Our results indicated that the DVH curves shifted toward higher dose side when larger cylinder was used instead of smaller ones. When 3.0 cm cylinder was used instead of 2.5 cm, for 3.0 cm treatment length, the average dose only increased 1%, from 790 to 799 cGy. However, the average doses for 3.5 and 4 cm cylinders respectively are 932 and 1137 cGy at the same treatment length. For 5.0 cm treatment length, the average dose is 741 cGy for 2.5 cm cylinder, and 859 cGy for 3 cm cylinder. Conclusion: Our data analysis suggests that for the vaginal intracavitary HDRBT, the average dose is at least 35% larger than the prescribed dose in the studied cases; the size of the cylinder will impact the dose delivered to the target volume. The cylinder with bigger diameter tends to deliver larger average dose to the PTV-Eval

  11. Late effects of ionizing radiations on vulva, vagina and uterus; Effets tardifs des radiations ionisantes sur la vulve, le vagin et l`uterus

    Energy Technology Data Exchange (ETDEWEB)

    Mazeron, J.J. [Groupe Hospitalier Pitie-Salpetriere, 75 - Paris (France); Gerbaulet, A. [Institut Gustave Roussy, 94 - Villejuif (France)

    1997-12-01

    Reporting and scoring complications after radiotherapy of gynaecological cancers is difficult because of the variety of treatment techniques involved. Use of an international classification is necessary to compare results obtained in series of patients treated in different institutions. An international group of experts designed in the early nineties the so-called French-Italian glossary. This classification of late effects is now completed with the new LENT SOMA scales. This paper contains details of these late changes, including their pathophysiology, clinical syndromes, potential treatment, and prevention. (authors)

  12. Characterization of cytological changes, IgA, IgG and IL-8 levels and pH value in the vagina of prepubertal and sexually mature Ellegaard Göttingen minipigs during an estrous cycle

    DEFF Research Database (Denmark)

    Lorenzen, Emma; Agerholm, Jørgen Steen; Grossi, Anette Blak; Bojesen, Anders Miki; Skytte, Christina; Erneholm, Karin; Follmann, Frank; Jungersen, Gregers

    2016-01-01

    The pig is increasingly used as an advanced animal model of the genital tract in women and knowledge on the genital immune system is therefore needed.In this study, evaluation of vaginal smears revealed that almost no neutrophils or other leukocytes were present in the vaginal mucosa of prepubert...

  13. Caracterización de la microbiota levaduriforme residente en la vagina de perras en diferentes fases del ciclo estral Characterization of vaginal microbiotic yeasts of bitches in distinct stages of the oestrous cycle

    OpenAIRE

    M B Cleff; M O Xavier; A A Martins; R. SANTIN; M C A Meireles

    2007-01-01

    Hongos levaduriformes son aislados frecuentemente de los animales domésticos y silvestres, siendo algunos comensales del tegumento y mucosas. Las levaduras son frecuentes en la mucosa vaginal de las mujeres, pero en perras son escasos los estudios referentes a la microbiota fúngica vaginal, sin conocerse su relación con el ciclo reproductivo. En este estudio se buscó aislar e identificar levaduras de la microbiota vaginal de perras, y establecer si hay alteración de la microbiota levaduriform...

  14. Vaginitis

    Science.gov (United States)

    ... led to advances in knowledge about the normal microflora of the vagina, reproductive behavior of yeast, and ... association between certain lactobacilli species in the normal microflora in the vagina and protection from bacterial vaginosis ( ...

  15. Condom

    Science.gov (United States)

    ... How Can I Help a Friend Who Cuts? Condom KidsHealth > For Teens > Condom Print A A A ... this happens, sperm could enter the vagina. Female Condom The female condom is inserted into the vagina ...

  16. Healthy Sexuality

    Medline Plus

    Full Text Available ... from the walls of the vagina. The vaginal muscles relax, causing the vagina to lengthen and widen. ... causing it to rise and stiffen. The smooth muscles of the scrotum contract, the skin of the ...

  17. Calendula

    Science.gov (United States)

    ... cancer. Thinning of the wall of the vagina (vaginal atrophy). Early research suggests that applying a specific gel ( ... the vagina for 4 weeks reduces symptoms of vaginal atrophy such as vaginal itching, burning, dryness, and pain ...

  18. General Information about Gestational Trophoblastic Disease

    Science.gov (United States)

    ... cervix , uterus, fallopian tubes, ovaries , and rectum . A speculum is inserted into the vagina and the doctor ... Enlarge Dilatation and curettage (D and C). A speculum is inserted into the vagina to widen it ...

  19. Gestational Trophoblastic Disease Treatment

    Science.gov (United States)

    ... cervix , uterus, fallopian tubes, ovaries , and rectum . A speculum is inserted into the vagina and the doctor ... Enlarge Dilatation and curettage (D and C). A speculum is inserted into the vagina to widen it ...

  20. Pap Test

    Science.gov (United States)

    ... female reproductive anatomy during a Pap test. A speculum is shown widening the opening of the vagina. ... and her feet in stirrups. Pap test. A speculum is inserted into the vagina to widen it. ...

  1. Surgical Tutorial of a Robotic-Assisted Anterior Pelvic Exenteration

    Medline Plus

    Full Text Available ... anterior vagina and it invading into the posterior bladder. To make matters a little more complicated, she ... is not involved, we would surgically remove the bladder, the anterior part of the vagina, the cervix ...

  2. How Many Cancers Are Linked with HPV Each Year?

    Science.gov (United States)

    ... the body include the cervix, anus, penis, vagina, vulva, and oropharynx (back of the throat, including the ... and many cancers of the anus, penis, vagina, vulva, and oropharynx. CDC studies 3 4 5 used ...

  3. Vaginitis - self-care

    Science.gov (United States)

    Vaginitis is a swelling or infection of the vulva and vagina. It may also be called vulvovaginitis. ... Lentz GM. Infections of the lower genital tract: vulva, vagina, cervix, toxic shock syndrome,endometritis, and salpingitis. ...

  4. What Is Vaginal Cancer?

    Science.gov (United States)

    ... of the uterus) to open up at the vulva (the external female genitals). The vagina is lined ... cancer. Likewise, if the cancer involves both the vulva and the vagina, it’s considered a vulvar cancer. ...

  5. Vaginal itching and discharge - Adult and adolescent

    Science.gov (United States)

    ... skin of the vagina and the surrounding area (vulva) may be present along with vaginal discharge. It ... blisters or other sores on your vagina or vulva. Have burning with urination or other urinary symptoms. ...

  6. [ABOUT UNIFICATION OF LABORATORY CRITERIA OF DIFFERENTIATION OF BACTERIAL VAGINOSIS].

    Science.gov (United States)

    Mavzutov, A R; Tsvetkova, A V; Muretdinova, L A

    2015-06-01

    The article presents analysis of laboratory criteria and classifcations used to interpret results of laboratory analysis by technique of microscopy on bacterial vaginosis or dysbacteriosis of vagina. Their advantages and restrictions are demonstrated The unified criteria of evaluation are proposed concerning results of microscopy of mucosal discharge of vagina and corresponding classification. Thereafter, three degrees of bacterial vaginosis (dysbacteriosis of vagina) are differentiated: first degree--compensated dysbacteriosis of vagina, second degree--sub compensated dysbacteriosis of vagina and third degree--decompensated dysbacteriosis of vagina. The corresponding laboratory report of physician is formulated. The proposals are presented concerning development of common unified requirements to stages (pre-analytical, analytical, post-analytical) of laboratory diagnostic of bacterial vaginosis (dysbacteriosis of vagina) with purpose of their unambiguous understanding by clinicians and hence their decision making concerning necessity and tactics of management of patient. PMID:26466451

  7. Comparative study vagina mould/ fletcher applicator in MRI guided pulsed rate brachytherapy in patients reached by an uterine cervix carcinoma; Etude comparative moule vaginal/applicateur de fletcher en curietherapie de debit pulse guide par IRM chez les patientes atteintes d'un cancer du col uterin

    Energy Technology Data Exchange (ETDEWEB)

    Francois, G.; Dumas, I.; Mazeron, R.; Verezesan, O.; Monnier, L.; Vieillot, S.; Gensse, M.C.; Haie-Meder, C. [Institut Gustave-Roussy, 94 - Villejuif (France)

    2009-10-15

    This study began in february 2009 and included until today ten patients. twenty patients are planned. The analysis of preliminary results show a much higher tolerance for the vaginal cast device. The dosimetry data were the object of a preliminary study that seems demonstrate an equivalence of the both modalities, with differences concerning the doses to critical organs; The definitive result swill be presented with the data including the twenty planned patients. (N.C.)

  8. Female Reproductive System

    Science.gov (United States)

    ... of the development period, and produce the female sex hormones. The female reproductive system includes the ovaries, Fallopian tubes, uterus, vagina, accessory glands, and external genital organs. ...

  9. Too Few Preteen Girls Get HPV Vaccine, CDC Says

    Science.gov (United States)

    ... vaccine protects against infection with the sexually transmitted human papillomavirus (HPV), which can cause cancers of the cervix, vulva, vagina and anus. "Increasing delivery of HPV vaccination at ...

  10. What Is Vulvar Cancer?

    Science.gov (United States)

    ... it, the opening of the urethra (the short tube that carries urine from the bladder). The Bartholin glands are found just inside the opening of the vagina -- one on each side. These glands produce a mucus-like fluid that acts as a lubricant during sex. At the front of the vagina, the labia ...

  11. Vaginal applicator with variable tips

    International Nuclear Information System (INIS)

    A new vaginal applicator with variable tips for intracavitary radiotherapy for cancer of the uterine cervix was devised. Both TAO and Henschke Type can be attached to it. With this applicator, injury of the vagina is avoided and tumor recurrence at the vagina will be reduced. (author)

  12. Vaginal applicator with variable tips

    Energy Technology Data Exchange (ETDEWEB)

    Kubota, Susumu; Furukawa, Shigeo; Nakamura, Yuzuru (National Inst. of Radiological Sciences, Chiba (Japan)); Sekiya, Toru; Shirakawa, Takako; Endo, Hisashi; Oda, Kurahiro; Akisada, Masayoshi

    1991-12-01

    A new vaginal applicator with variable tips for intracavitary radiotherapy for cancer of the uterine cervix was devised. Both TAO and Henschke Type can be attached to it. With this applicator, injury of the vagina is avoided and tumor recurrence at the vagina will be reduced. (author).

  13. Hysterosalpingography

    Science.gov (United States)

    ... during a pelvic exam. A tool called a speculum is placed into the vagina . After the cervix ... You may have some discomfort when the speculum is inserted into the vagina. This is similar to a pelvic exam with a Pap smear. Some women have cramps during or after ...

  14. Apical blebs on sperm-storage tubule epithelial cell microvilli: their release and interaction with resident sperm in the turkey hen oviduct

    Science.gov (United States)

    Technical Abstract: Located at the anterior end of the turkey hen vagina are numerous discrete tubular invaginations of the surface epithelium, collectively referred to as the sperm-storage tubules (SSTs). Following mating or artificial insemination, sperm ascend the vagina, enter the SSTs, and ove...

  15. 21 CFR 250.108 - Potassium permanganate preparations as prescription drugs.

    Science.gov (United States)

    2010-04-01

    ... AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL SPECIAL REQUIREMENTS FOR SPECIFIC HUMAN DRUGS New Drug... crystals of potassium permanganate into the vagina. Experience with these cases shows that such use of... and painful injury to the walls of the vagina, causing ulcers, massive hemorrhage, and infection....

  16. Treatment Options by Stage (Vaginal Cancer)

    Science.gov (United States)

    ... in the groin may be removed. Pelvic exenteration : Surgery to remove the lower colon , rectum , bladder , cervix, vagina, and ovaries . Nearby lymph nodes are also removed. Artificial openings ( stoma ) are made for urine and ... grafting may follow surgery, to repair or reconstruct the vagina. Skin grafting ...

  17. Stages of Vaginal Cancer

    Science.gov (United States)

    ... in the groin may be removed. Pelvic exenteration : Surgery to remove the lower colon , rectum , bladder , cervix, vagina, and ovaries . Nearby lymph nodes are also removed. Artificial openings ( stoma ) are made for urine and ... grafting may follow surgery, to repair or reconstruct the vagina. Skin grafting ...

  18. General Information about Vaginal Cancer

    Science.gov (United States)

    ... in the groin may be removed. Pelvic exenteration : Surgery to remove the lower colon , rectum , bladder , cervix, vagina, and ovaries . Nearby lymph nodes are also removed. Artificial openings ( stoma ) are made for urine and ... grafting may follow surgery, to repair or reconstruct the vagina. Skin grafting ...

  19. General Information about Cervical Cancer

    Science.gov (United States)

    ... both ovaries and both fallopian tubes. Pelvic exenteration : Surgery to remove the lower colon , rectum , and bladder . The cervix, vagina, ovaries, and nearby lymph nodes are also removed. Artificial openings ( stoma ) are made for ... a collection bag. Plastic surgery may be needed to make an artificial vagina ...

  20. Treatment Option Overview (Vaginal Cancer)

    Science.gov (United States)

    ... in the groin may be removed. Pelvic exenteration : Surgery to remove the lower colon , rectum , bladder , cervix, vagina, and ovaries . Nearby lymph nodes are also removed. Artificial openings ( stoma ) are made for urine and ... grafting may follow surgery, to repair or reconstruct the vagina. Skin grafting ...

  1. Wnt family genes and their modulation in the ovary-independent and persistent vaginal epithelial cell proliferation and keratinization induced by neonatal diethylstilbestrol exposure in mice

    International Nuclear Information System (INIS)

    Proliferation and differentiation of cells in female reproductive organs, the oviduct, uterus and vagina, are regulated by endogenous estrogen. In utero exposure to a synthetic estrogen, diethylstilbestrol (DES), induces vaginal clear-cell adenocarcinoma in humans. In mice, perinatal exposure to DES results in abnormalities such as polyovular follicles, uterine circular muscle disorganization and persistent vaginal epithelial cell proliferation. We reported the persistent gene expression change such as interleukin-1 (IL-1) related genes, insulin-like growth factor-I (IGF-I) and its downstream signaling in the mouse vagina exposed neonatally to DES. In this study, we found persistent up-regulation of Wnt4 and persistent down-regulation of Wnt11 in the vagina of mice exposed neonatally to DES and estrogen receptor ? specific ligand. Also Wnt4 expression in vagina is correlated to the stratification of epithelial cells with the superficial keratinization of vagina, but not epithelial cell stratification only.

  2. Progesterone receptors in the female lower urinary tract

    Energy Technology Data Exchange (ETDEWEB)

    Batra, S.C.; Iosif, C.S.

    1987-11-01

    When female estrogenized rabbits were injected i.v. with /sup 3/H-progesterone, the tritium concentration determined after one hour was about two to three times higher in urethra, urinary bladder and vagina than in the heart. High affinity progesterone receptors (KD = 1-2 nM) could be demonstrated in both cytoplasmic and nuclear fractions prepared from estrogenized rabbit urethra, bladder and vagina. The cytosolic receptor concentration in both urethra and bladder was about half of that in the vagina. The concentration of nuclear receptors in urethra was not significantly different from that in the vagina, but in the bladder the concentration was only about one fourth of that in the vagina or urethra. The mean KD of cytosolic receptors from bladder was significantly higher than the corresponding values in urethra and vagina. Progesterone binding sites in the bladder had a broader hormonal specificity than those in the urethra or vagina. The present demonstration of specific progesterone receptors in the female urethra might provide a possible link between estrogen progesterone interaction and the appearance of urinary incontinence during pregnancy in women.

  3. Progesterone receptors in the female lower urinary tract

    International Nuclear Information System (INIS)

    When female estrogenized rabbits were injected i.v. with 3H-progesterone, the tritium concentration determined after one hour was about two to three times higher in urethra, urinary bladder and vagina than in the heart. High affinity progesterone receptors (KD = 1-2 nM) could be demonstrated in both cytoplasmic and nuclear fractions prepared from estrogenized rabbit urethra, bladder and vagina. The cytosolic receptor concentration in both urethra and bladder was about half of that in the vagina. The concentration of nuclear receptors in urethra was not significantly different from that in the vagina, but in the bladder the concentration was only about one fourth of that in the vagina or urethra. The mean KD of cytosolic receptors from bladder was significantly higher than the corresponding values in urethra and vagina. Progesterone binding sites in the bladder had a broader hormonal specificity than those in the urethra or vagina. The present demonstration of specific progesterone receptors in the female urethra might provide a possible link between estrogen progesterone interaction and the appearance of urinary incontinence during pregnancy in women

  4. Sexual Problems

    Medline Plus

    Full Text Available ... occur with entry into the vagina or as deep pain. Both psychological and physical factors can contribute ... oil-based products. Water-based lubricants have the advantage of being nonstaining. Silicone-based lubricants stay slippery ...

  5. Laparoscopic Supracervical Hysterectomy

    Medline Plus

    Full Text Available ... that we will see less prolapse or less relaxation and…and dropping of the pelvic organs if ... cervix or the cervix started to prolapse or relax out through the opening of the vagina, there ...

  6. Gestational diabetes

    Science.gov (United States)

    ... symptoms are present they may include: Blurred vision Fatigue Frequent infections, including those of the bladder, vagina, ... putting a drop of your blood on a machine that will give you a glucose reading.

  7. Endometriosis

    Medline Plus

    Full Text Available ... abnormal endometrium can grow on or into other organs causing an inflammatory response that can lead to ... In severe cases, endometriosis can grow into other organs including the intestines, bladder, vagina and ureters, which ...

  8. Urinary Tract Infections

    Science.gov (United States)

    ... have shorter urethras than guys, and the opening lies closer to the rectum and vagina where bacteria ... 1 • 2 • 3 • 4 • 5 For Teens For Kids For Parents MORE ON THIS TOPIC Dehydration Understanding ...

  9. Sexual Problems

    Medline Plus

    Full Text Available ... occur with entry into the vagina or as deep pain. Both psychological and physical factors can contribute ... All Rights Reserved. ASRM Non Discrimination Policy | ASRM Web Site Terms & Conditions of Use | Web Design and ...

  10. Optimizing Male Fertility

    Science.gov (United States)

    ... an egg is released (ovulation). Are there coital (sex) practices that can improve our chances of conceiving? Sperm ejaculated into the vagina reaches the fallopian tubes within minutes regardless of position during intercourse. Also, ...

  11. Vulvovaginal Health

    Science.gov (United States)

    ... the vagina of the female (also called “having sex” or “making love”). Skene Glands: Glands located on either side of the urethral opening. Urethra: A tube-like structure through which urine flows from the ...

  12. Penile Trauma

    Science.gov (United States)

    ... What is Urology? The Urinary Tract System Free Patient Education Materials We provide free patient education materials on ... be ejaculated into the vagina. Share Causes Advertisement Patient Education Materials We provide free patient education materials on ...

  13. Ultrasound -- Pelvis

    Medline Plus

    Full Text Available ... the radiologist or sonographer will apply a warm water-based gel to the area of the body ... into the vagina. The images are obtained from different orientations to get the best views of the ...

  14. Dyspareunia: Painful Sex for Women

    Science.gov (United States)

    ... part of the genitals can cause pain during sex. Some conditions affect the skin around the vagina. ... types of birth control) does not fit correctly, sex may also be painful. Vaginismus (say: "vag-in- ...

  15. Robotic-Assisted Laparoscopic Sacrocolpopexy for Vaginal Vault Prolapse

    Medline Plus

    Full Text Available ... of the art procedure to surgically correct vaginal vault prolapse by resupporting the vagina to the sacrum ... is a 60-year-old patient with vaginal vault prolapse, and despite our diligent attempt at obtaining ...

  16. Vaginal tumors

    Science.gov (United States)

    Vaginal cancer; Cancer - vagina; Tumor - vaginal ... Most cancerous vaginal tumors occur when another cancer, such as cervical or endometrial cancer , spreads. This is called secondary vaginal cancer. Primary vaginal ...

  17. Surgical Tutorial of a Robotic-Assisted Anterior Pelvic Exenteration

    Medline Plus

    Full Text Available ... vagina, the cervix and surrounding tissues as well last the uterus and both tubes and ovaries. In ... the instrumentation and of our vision as well last our ability to minimize bleeding for the same ...

  18. Surgical Tutorial of a Robotic-Assisted Anterior Pelvic Exenteration

    Medline Plus

    Full Text Available ... well last the uterus and both tubes and ovaries. In addition to that, we perform a quite ... end of the pelvis, remove the uterus, tubes, ovaries, surrounding issues, the majority of the anterior vagina ...

  19. Robot-Assisted Gynecologic Oncology Surgery

    Medline Plus

    Full Text Available ... paramount. But if we -- you know, my career goal is to do away with open surgery. I ... deliver that through the vagina without too much difficulty. The uterus is kind of big -- and it's ...

  20. Robot-Assisted Gynecologic Oncology Surgery

    Medline Plus

    Full Text Available ... in more endometrial cancers. So for example, early start of your period, late menopause, you've had ... against the cap. So we are going to start a colpotomy, which is opening the vagina, separating ...

  1. Metronidazole Oral

    Science.gov (United States)

    Metronidazole eliminates bacteria and other microorganisms that cause infections of the reproductive system, gastrointestinal tract, skin, vagina, ... Metronidazole comes as a tablet to take by mouth. It is usually taken two or three times ...

  2. Cytology exam of urine

    Science.gov (United States)

    Urine cytology ... time, the sample is collected as clean catch urine sample in your doctor's office or at home. ... the penis or vagina from getting into a urine sample. To collect your urine, the health care ...

  3. Immunoelectrophoresis - urine

    Science.gov (United States)

    Immunoglobulin electrophoresis - urine; Gamma globulin electrophoresis - urine; Urine immunoglobulin electrophoresis; IEP - urine ... A clean-catch urine sample is needed. The clean-catch method is used to prevent germs from the penis or vagina from getting ...

  4. Vaginal Yeast Infections (For Parents)

    Science.gov (United States)

    ... infection caused by a type of fungus called candida albicans . Yeast infections usually happen in warm, moist parts of the body, like the mouth, or vagina. We all have candida in our bodies, but usually it's kept in ...

  5. Vaginal Yeast Infection

    Science.gov (United States)

    ... Centers for Diseases Control and Prevention. Micrograph showing Candida albicans from a patient with vaginal candidiasis, also known ... caused by an overgrowth of a fungus called Candida albicans in the vagina. Candida is yeast, which is ...

  6. Surgical Tutorial of a Robotic-Assisted Anterior Pelvic Exenteration

    Medline Plus

    Full Text Available ... to you by Intuitive Surgical. During the program, it’s easy for you to learn about the procedure. ... of the cervix and the anterior vagina and it invading into the posterior bladder. To make matters ...

  7. Sonohysterography

    Science.gov (United States)

    ... transvaginal ultrasound exam, the transducer is removed. A speculum is placed in the vagina. It holds the ... as that lining the inside of the uterus. Speculum: An instrument used to hold open the walls ...

  8. Vaginitis test - wet mount

    Science.gov (United States)

    ... The health care provider gently inserts an instrument (speculum) into the vagina to hold it open so ... take a sample of discharge. The swab and speculum are removed. The discharge is sent to a ...

  9. Dilation and Curettage

    Science.gov (United States)

    ... your legs will be placed in stirrups. A speculum will be inserted into your vagina. The cervix ... cervix to widen it. Miscarriage: Early pregnancy loss. Speculum: An instrument used to hold open the walls ...

  10. Hysteroscopy

    Science.gov (United States)

    ... cervix , or special dilators may be used. A speculum is first inserted into the vagina. The hysteroscope ... part of the body. Miscarriage: Early pregnancy loss. Speculum: An instrument used to open the walls of ...

  11. Can Vulvar Cancer Be Prevented?

    Science.gov (United States)

    ... abnormalities. The health care professional then places a speculum inside the vagina. A speculum is a metal or plastic instrument that keeps ... to the body of the uterus). Then, the speculum is removed. The doctor then will check the ...

  12. Stages of Uterine Sarcoma

    Science.gov (United States)

    ... Other Funding Find NCI funding for small business innovation, technology transfer, and contracts Training Cancer Training at ... vagina and used to bounce high-energy sound waves ( ultrasound ) off internal tissues or organs and make ...

  13. Stages of Endometrial Cancer

    Science.gov (United States)

    ... Other Funding Find NCI funding for small business innovation, technology transfer, and contracts Training Cancer Training at ... vagina and used to bounce high-energy sound waves (ultrasound) off internal tissues or organs and make ...

  14. Treatment Options by Stage (Endometrial Cancer)

    Science.gov (United States)

    ... Other Funding Find NCI funding for small business innovation, technology transfer, and contracts Training Cancer Training at ... vagina and used to bounce high-energy sound waves (ultrasound) off internal tissues or organs and make ...

  15. Treatment Options by Stage (Uterine Sarcoma)

    Science.gov (United States)

    ... Other Funding Find NCI funding for small business innovation, technology transfer, and contracts Training Cancer Training at ... vagina and used to bounce high-energy sound waves ( ultrasound ) off internal tissues or organs and make ...

  16. Treatment Option Overview (Uterine Sarcoma)

    Science.gov (United States)

    ... Other Funding Find NCI funding for small business innovation, technology transfer, and contracts Training Cancer Training at ... vagina and used to bounce high-energy sound waves ( ultrasound ) off internal tissues or organs and make ...

  17. Treatment Option Overview (Endometrial Cancer)

    Science.gov (United States)

    ... Other Funding Find NCI funding for small business innovation, technology transfer, and contracts Training Cancer Training at ... vagina and used to bounce high-energy sound waves (ultrasound) off internal tissues or organs and make ...

  18. General Information About Uterine Sarcoma

    Science.gov (United States)

    ... Other Funding Find NCI funding for small business innovation, technology transfer, and contracts Training Cancer Training at ... vagina and used to bounce high-energy sound waves ( ultrasound ) off internal tissues or organs and make ...

  19. General Information About Endometrial Cancer

    Science.gov (United States)

    ... Other Funding Find NCI funding for small business innovation, technology transfer, and contracts Training Cancer Training at ... vagina and used to bounce high-energy sound waves (ultrasound) off internal tissues or organs and make ...

  20. Medications for Inducing Ovulation

    Science.gov (United States)

    ... Cervix Cmeruvciucsal Vagina Egg released (ovulated) Figure 1. Diagram showing ovulation. Fertilization usually occurs in the fallopian ... of infertile patients that is most likely to benefit from ovulation induction with fertility drugs. Clomiphene citrate ...

  1. Pelvic Floor Dysfunction

    Science.gov (United States)

    ... the rectum bulges forwards into the vagina. Rectocele Diagram Courtesy of Robin Noel Hospital of the University ... creating a sharp angle in the rectum that helps to prevent passive leakage of stool. During the ...

  2. Endometriosis

    Medline Plus

    Full Text Available ... can grow into other organs including the intestines, bladder, vagina and ureters, which are the tubes from the kidney to the bladder. Although it’s rare, endometriosis can be found outside ...

  3. Fístula vesicovaginal continente / Continent vesicovaginal fistula

    Scientific Electronic Library Online (English)

    Luís Gustavo Morato de, Toledo; Victor Espinheira, Santos; Paulo Eduardo Gourlat, Maron; Bruno César, Vedovato; Moacyr, Fucs; Marjo Deninson Cardenuto, Perez.

    2013-03-01

    Full Text Available A fístula vesicovaginal é uma comunicação anormal entre a bexiga e a vagina, sendo o tipo mais comum de fístula do trato urinário. A causa mais frequente no Brasil é a iatrogênica, secundária à histerectomia. Classicamente, as mulheres nessa condição, apresentam perda urinária contínua pela vagina e [...] ausência de micção, com forte impacto negativo na qualidade de vida. Apresentamos um caso de fístula vesicovaginal totalmente continente, com seguimento de 11 anos, sem complicações. Abstract in english Vesicovaginal fistula is an abnormal communication between the bladder and vagina and represents the most frequent type of fistula in the urinary tract. The most common cause in Brazil is iatrogenic fistula, secondary to histerectomia. Classically these women present continuous urinary leakage from [...] the vagina and absence of micturition, with strong negative impact on their quality of life. We present a case of totally continent vesicovaginal fistula, with a follow-up of 11 years with no complications.

  4. Microflora of urogenital tract in pregnancy with asymptomatic bacterium

    International Nuclear Information System (INIS)

    The article contains results of research interrelationship from colonization of vagina and urinary tract diseases. E.coli one of the main factors in development asymptomatic bacterium. Presented high effects of penicillin medicaments and nitrofurans in treatment of asymptomatic bacterium

  5. Loop Electrosurgical Excision Procedure (LEEP)

    Science.gov (United States)

    ... human papillomavirus infection, herpes, syphilis, and infection with human immunodeficiency virus (HIV, the cause of acquired immunodeficiency syndrome [AIDS]). Speculum: An instrument used to hold apart the walls of the vagina so that the cervix can be seen. If ...

  6. Surgical Tutorial of a Robotic-Assisted Anterior Pelvic Exenteration

    Medline Plus

    Full Text Available ... See this is a beautiful example of the human anatomy here. You can see the endopul fascia ... Sometimes the manipulation of the retractor in the vagina can help us locate this. But in this ...

  7. Hysterectomy

    Science.gov (United States)

    ... Uterine prolapse - when the uterus drops into the vagina Cancer of the uterine, cervix, or ovaries Vaginal bleeding that persists despite treatment Chronic pelvic pain, as a last resort Dept. of Health and Human Services Office on Women's Health

  8. Dealing with Pain during Childbirth

    Science.gov (United States)

    ... and the stretching of the birth canal and vagina. Pain during labor is different for every woman. Although labor is often thought of as one of the more painful events in human experience, it ranges widely from woman to woman ...

  9. Cancer prevention: take charge of your lifestyle

    Science.gov (United States)

    ... provider about whether you should have these vaccinations: Human Papillomavirus (HPV). The virus increases the risk for cancers of the cervix, penis, vagina, anus, and throat. Hepatitis B and hepatitis C. ...

  10. Robot-Assisted Gynecologic Oncology Surgery

    Medline Plus

    Full Text Available ... weeks even, before we actually ever touch a human patient. And that's the beauty of the da ... the junction between the cervix and the upper vagina. And I'm trying to -- sometimes it's really ...

  11. Genital Human Papillomavirus (HPV) Infection in Women

    Science.gov (United States)

    Genital Human Papillomavirus (HPV) Infection in Women What is HPV? HPV is human papillomavirus. It is the most common viral sexually ... on the cervix (opening to the uterus) or vagina. “High risk” HPV can also cause precancerous changes ...

  12. Robot-Assisted Gynecologic Surgery

    Medline Plus

    Full Text Available ... system completely eradicates all normal tremor that a human hand might have. And as a standard laparoscopic ... between the cervix and the top of the vagina. So now, we use that cap while we ...

  13. Sexual Problems

    Medline Plus

    Full Text Available ... may be due to many factors, including physical, psychological, medical conditions, or medications. Men with male orgasmic ... into the vagina or as deep pain. Both psychological and physical factors can contribute to the condition. ...

  14. Locally aggressive colonic and rectal cancer ,clinical trial

    OpenAIRE

    Radu, V; Ion, D; ?erban, MB; Ciurea, M.

    2010-01-01

    This clinical trial studies local invasions from primary colonic and rectal cancers (urinary bladder, abdominal wall, small bowls, uterus, vagina, stomach, bile tract, spleen, duodenum, pancreas, ureters, kidneys), with or without undiscovered metastasis.

  15. Robotic-Assisted Laparoscopic Sacrocolpopexy for Vaginal Vault Prolapse

    Medline Plus

    Full Text Available ... of the vasculature. Middle sacral vessels line the space as well as a number of venous plexuses, ... reasons. One would be difficulty dissecting the presacral space, difficulty suturing the mesh to the vagina and ...

  16. Bartholin cyst or abscess

    Science.gov (United States)

    ... and swollen. Activity that puts pressure on the vulva , and walking and sitting, may cause severe pain. ... Lentz GM. Infections of the lower genital tract: vulva, vagina, cervix, toxic shock syndrome, endometritis, and salpingitis. ...

  17. Dealing with Sexual Problems

    Science.gov (United States)

    ... cystectomy Abdominoperineal resection Surgery for cancer of the vulva (vulvectomy) Pelvic exenteration Sex and pelvic radiation therapy ... for intercourse has changed. If your vagina or vulva has been affected by surgery, you will need ...

  18. Medications for Pain Relief during Labor and Delivery

    Science.gov (United States)

    ... the nerves that carry feeling to the vagina , vulva , and perineum . The drugs are given just before ... the uterus to the outside of the body. Vulva: The external female genital area. If you have ...

  19. Endometrial Ablation

    Science.gov (United States)

    ... is a risk of burns to the vagina, vulva , and bowel. Rarely, the fluid used to expand ... contains and nourishes the developing fetus during pregnancy. Vulva: The external female genital area. If you have ...

  20. Lymphogranuloma venereum

    Science.gov (United States)

    ... lymph nodes in the groin Swelling of the vulva or labia in women Swollen lymph nodes in ... Lentz GM. Infections of the lower genital tract: vulva, vagina, cervix, toxic shock syndrome, endometritis, and salpingitis. ...

  1. Cervical cancer

    Science.gov (United States)

    ... Seiden MV, et al. Cancers of the cervix, vulva, and vagina. In: Niederhuber JE, Armitage JO, Doroshow ... Intraepithelial neoplasia of the lower genital tract (cervix, vulva): Etiology, screening, diagnostic techniques, management. In: Katz VL, ...

  2. Vaginal Discharge

    Science.gov (United States)

    ... cheese-like discharge Swelling and pain around the vulva Intense itching Painful sexual intercourse Signs of bacterial ... Slight redness and swelling of the vagina or vulva Signs of trichomoniasis A watery, yellowish or greenish ...

  3. Gonorrhea, Chlamydia, and Syphilis

    Science.gov (United States)

    ... chancre . Because this sore commonly occurs on the vulva , vagina, anus, or penis, syphilis most often is ... hands. Flat warts may be seen on the vulva. During this stage, there may be flu-like ...

  4. Use of a Flexible Inflatable Multi-Channel Applicator for Vaginal Brachytherapy in the Management of Gynecologic Cancer

    OpenAIRE

    Shin, Samuel M.; Duckworth, Tamara L.; Cooper, Benjamin T; Curtin, John P.; Schiff, Peter B.; DeWyngaert, J. Keith; Lymberis, Stella C.

    2015-01-01

    Introduction Evaluate use of novel multi-channel applicator (MC) Capri™ to improve vaginal disease coverage achievable by single-channel applicator (SC) and comparable to Syed plan simulation. Materials and methods Twenty-eight plans were evaluated from four patients with primary or recurrent gynecologic cancer in the vagina. Each received whole pelvis radiation, followed by three weekly treatments using HDR brachytherapy with a 13-channel MC. Upper vagina was treated to 5?mm depth...

  5. Anatomia e histologia do conduto genital feminino de Pomacea canaliculata (Lamarck, 1822) (Mollusca, Gastropoda, Pilidae)

    OpenAIRE

    Eliana de Fátima Marques de Mesquita; Arnaldo Campos dos Santos Coelho; Jefferson Andrade dos Santos

    1990-01-01

    In this paper the authors give an anatomical and histological analysis of the genital duct in mature and immature females of Pomacea canaliculata (Lamarck, 1822). Anatomically, the vagina has an equal dimension in its extension, varying in form and volume, according to the maturation period. In the immaturity, it has a smaller diameter and volume. In the maturity, the vagina increases in volume, having the aspect of a tumescent organ, and in certain specimens shows an albuminous pink thread i...

  6. Sobre a anatomia do sistema genital de Bradybaena similaris (Férussac, 1821 (Pulmonata, Stylommatophora, Bradybaenidae ocorrentes em Porto Alegre, estado do Rio Grande do Sul, Brasil

    Directory of Open Access Journals (Sweden)

    Mônica Picoral

    1989-01-01

    Full Text Available Com base em material coletado em Porto Alegre, apresenta-se um estudo anatômico detalhado do sistema genital de Bradybena similaris (Férussac, 1821, comparado com trabalhos anteriores, propondo-se uma padronização da nomenclatura dos diversos órgãos e regiões, destacando-se a estrutura da região da encruzilhada ("carrefour", do ovispermioducto até a vagina e do pênis e assinalando-se a independência das aberturas do pênis, vagina e saco do dardo num átrio genital.

  7. Bladder and kidney function after cure of pelvic rhabdomyosarcoma in childhood.

    OpenAIRE

    Yeung, C. K.; Ward, H.C.; Ransley, P G; Duffy, P.G.; Pritchard, J.

    1994-01-01

    Eleven survivors of pelvic rhabdomyosarcoma underwent bladder function studies and upper urinary tract evaluation at a mean of 6.6 years after completion of therapy, which included a conservative, bladder-sparing surgical policy. Primary tumour sites were: bladder base/prostate, 6; bladder dome, 1; vagina, 2; and pelvic side wall, 2. Seven children (five bladder base/prostate, one vagina and one pelvic side wall tumours) had received irradiation to the pelvis with external beam alone, brachyt...

  8. Histología uretral y vaginal en algunas hembras de mamíferos / Urethral and vaginal histology in some female mammals

    Scientific Electronic Library Online (English)

    J, Rodríguez-Antolín; E, Cuevas; L, Nicolás; V, Fajardo; F, Castelán; M, Martínez-Gómez.

    2012-04-01

    Full Text Available El análisis de las características histológicas de la uretra y la vagina en hembras de mamíferos es útil para entender la fisiología y la patología de procesos como la continencia urinaria, la cópula y el parto. En este contexto, las especies más estudiadas en cuanto a la organización tisular de la [...] uretra y vagina son la rata y la coneja. Es necesario estudiar con más detalle la organización tisular de la vagina y uretra en diferentes especies con fines de comparación. Tal información permitiría entender la diversidad funcional y conductual asociada a estos órganos. El presente documento reúne, compara y discute la información existente sobre las características histológicas de la uretra y la vagina en algunas hembras de mamíferos destacando aquellas de la coneja, modelo utilizado por nuestro grupo de investigación para estudiar la fisiología reproductiva y urinaria femenina. Abstract in english The analysis of the histological characteristics of the urethra and the vagina in female mammals is useful in understanding the physiology and pathology of processes such as urinary continence, copulation and delivery. In this regard, the species most studied with respect to the histological organis [...] ation of the urethra and vagina, are the rat and the rabbit. For comparative purposes, it is necessary to study in greater detail the histological organisation of the urethra and vagina in different species. The information gathered could help understand the functional and behavioural diversity associated with these organs. This study gathers, compares and discusses the existing information on the histological characteristics of the urethra and vagina in some mammal females, with emphasis on those of the rabbit, a model used by our research group to study female reproductive and urinary physiology.

  9. Magnetic resonance imaging of vaginal and vulval pathology

    International Nuclear Information System (INIS)

    There are a number of conditions affecting the vagina and vulva that can be optimally assessed with the use of high-resolution magnetic resonance imaging (MRI). This paper gives a suggested protocol for MRI technique and sequences for imaging the pelvis and perineum and reviews the MRI appearances of many of the common pathologies affecting the vagina and vulva. Congenital anomalies, inflammatory and neoplastic entities such as vaginal and vulval carcinoma are discussed, with rarer malignancies also reviewed. (orig.)

  10. Magnetic resonance imaging of vaginal and vulval pathology

    Energy Technology Data Exchange (ETDEWEB)

    Griffin, N.; Grant, L.A.; Sala, E. [Addenbrooke' s Hospital, Department of Radiology, Box 219, Cambridge (United Kingdom)

    2008-06-15

    There are a number of conditions affecting the vagina and vulva that can be optimally assessed with the use of high-resolution magnetic resonance imaging (MRI). This paper gives a suggested protocol for MRI technique and sequences for imaging the pelvis and perineum and reviews the MRI appearances of many of the common pathologies affecting the vagina and vulva. Congenital anomalies, inflammatory and neoplastic entities such as vaginal and vulval carcinoma are discussed, with rarer malignancies also reviewed. (orig.)

  11. Vaginal position and length in the bitch: relationship to spaying and urinary incontinence

    International Nuclear Information System (INIS)

    A study was undertaken to determine if the vagina might be a suitable site for the measurement of intra-abdominal pressure during cystometry in the bitch, The position of the cranial vagina and vaginal length were measured radiographically and the effects of spaying and urinary Incontinence on these variables were evaluated in 30 continent and 30 incontinent bitches. The study used retrograde vaginourethrograms which had been obtained from animals used in a previous study, The cranial vagina was intra-abdominal on 36 of the vaginourethrograms, being least commonly intra-abdominal in incontinent bitches (11/30), Vaginal position was related linearly to vaginal length and continence status (P<0.01), while its length was related to bodyweight(P<0.01). Allowing for bodyweight, neutered animals had significantly shorter vaginas than entire bitches (P<0.01). Measurement of intra-abdominal pressure with concomitant measurement of intravesical pressure is essential if accurate assessment of detrusor pressure is to be determined during cystometry, The vagina is unlikely to be a useful location from which to measure intra-abdominal pressure since any pressure-measuring catheter inserted into it may fall outside the abdominal pressure zone. This is particularly true of neutered and/or incontinent bitches, the groups in which urodynamic investigations of urinary incontinence are most frequently indicated

  12. Distribution of a spermicide containing Nonoxynol-9 in the vaginal canal and the upper female reproductive tract.

    Science.gov (United States)

    Barnhart, K T; Stolpen, A; Pretorius, E S; Malamud, D

    2001-06-01

    Topical, intravaginal microbicides and spermicides are greatly needed to prevent transmission of sexually transmitted diseases and/or unwanted pregnancies. The development of such compounds is a high research priority. The presumed method of action of existing, or novel, microbicides/spermicides is to provide a chemical barrier to the vaginal epithelium preventing exposure to micro-organisms. Other intravaginal products are used to treat vaginal bacteria of fungal infections. Little is known, however, about the actual or optimal initial distribution and subsequent spread of medications placed in the vagina. We describe a sensitive new technique to quantify the spread of a gel placed in the vagina using magnetic resonance imaging (MRI). Five millilitres of an over-the-counter spermicide containing Nonoxynol-9 was mixed with Gadolinium. MRI was used to quantify spread of the mixture 10 min after insertion with a standard applicator. We demonstrated contiguous spread of gel throughout the vagina. The coverage of material was thicker in the upper vagina than in the lower vagina. We also demonstrated, for the first time, that spermicidal compounds may migrate from the vaginal canal into the endocervix within 10 min of insertion. This finding suggests that topical microbicides/spermicides may act both in the vaginal canal and in the upper female genital tract. PMID:11387285

  13. Anatomia e histologia do conduto genital feminino de Pomacea canaliculata (Lamarck, 1822 (Mollusca, Gastropoda, Pilidae

    Directory of Open Access Journals (Sweden)

    Eliana de Fátima Marques de Mesquita

    1990-01-01

    Full Text Available In this paper the authors give an anatomical and histological analysis of the genital duct in mature and immature females of Pomacea canaliculata (Lamarck, 1822. Anatomically, the vagina has an equal dimension in its extension, varying in form and volume, according to the maturation period. In the immaturity, it has a smaller diameter and volume. In the maturity, the vagina increases in volume, having the aspect of a tumescent organ, and in certain specimens shows an albuminous pink thread in its lumen. Histologically, the calcigenic activity of the gland is evidentiated by the presence of an amorphous and basophilic mass, without nuclear material. This material has a fragmented aspect in the vagina lumen that reacts positively in van Kossa's coloured preparations for calcareous salts.

  14. A rare case of Turner?s syndrome presenting with Mullerian agenesis

    Directory of Open Access Journals (Sweden)

    Suresh Vaddadi

    2013-01-01

    Full Text Available Turner?s syndrome also called as Ullrich Turner?s syndrome, is a disease of unclear pathogenesis characterized by complete or partial absence of one sex chromosome, with or without cell line mosaicism in a phenotypic female with short stature. Various anomalies result in a constellation of features, of which the most disturbing is primary amenorrhea due to gonadal dysgenesis. Hormone therapy in these patients can often result in successful menstruation, and scope for subsequent pregnancy because of anatomically normal uterus and vagina. Coexisting Mullerian agenesis in these patients can jeopardize the chances of future pregnancy as they have associated structural abnormalities of the uterus and vagina. We report a rare case of middle-aged female with Turner?s syndrome and Mullerian agenesis having absent secondary sexual characters and missing uterus with incompletely formed vagina.

  15. HERLYN - WERNER - WUNDERLICH SYNDROME (HWW SYNDROME: A CASE REPORT

    Directory of Open Access Journals (Sweden)

    Pallavi S

    2015-08-01

    Full Text Available Congenital anomalies of the mullerian duct system can result in various urogenital anomalies and, Herlyn Werner Wunderlich syndrome (HWW syndrome is one such rare anomaly . This syndrome is characterized by uterus didelphys with blind hemi vagina and ipsilateral renal agenesis . 1 it is also known as OHVIRA (Obstructed Hemi vagina with Ipsilateral Renal Anomaly syndrome . 2 Mullerian anomalies are frequently associated with renal anomalies, the incidence ranges from 0.2 to 7.4%. 3 Diagnosis of this condition is rarely made in prepubertal girls, and rather it is diagnosed after menarche. Common clinical presentation is pelvic pain shortly after menarche with an associated vaginal or pelvic mass. 4 this triad of obstructed hemi vagina, uterus didelphys and ipsilateral renal agenesis was first reported in 1950.

  16. New laparoscopic peritoneal pull-through vaginoplasty technique

    Directory of Open Access Journals (Sweden)

    Pravin Mhatre

    2014-01-01

    Full Text Available Background: Many reconstructive surgical procedures have been described for vaginal agenesis. Almost all of them are surgically challenging, multi-staged, time consuming or leave permanent scars on abdomen or skin retrieval sites. Aim: A new simple technique using laparoscopic peritoneal pull-through in creation of neo vagina has been described. Material and Methods: Total of thirty six patients with congenital absence of vagina (MRKH syndrome were treated with laparoscopic peritoneal pull through technique of Dr. Mhatre between 2003 till 2012. The author has described 3 different techniques of peritoneal vaginoplasty. Results: This technique has given excellent results over a period of one to seven years of follow-up. The peritoneal lining changes to stratified squamous epithelium resembling normal vagina and having acidic Ph. Conclusion: Apart from giving excellent normal vaginal function, as the ovary became accessible per vaginum three patients underwent ovum retrieval and pregnancy using surrogate mother, thus making this a fertility enhancing procedure.

  17. Posterior vaginal wall cyst of Mullerian origin: a case report

    Directory of Open Access Journals (Sweden)

    Sunita Samal

    2015-02-01

    Full Text Available Cystic lesions of vagina are relatively uncommon and an incidental finding during routine gynaecological examination. Mullerian cysts are congenital cysts of vagina, usually reported during childbearing age group. These cysts mostly arise at the level of cervix and extend anteriorly in relation to bladder, but very rarely they may also extend posteriorly. This is a rare case of posterior vaginal wall cyst of Mullerian origin. A 36-year-old multi para (P2L2 both SVD, presented with a mass descending through vagina since 2-3 months. Pelvic examination revealed a 5x5 cm cystic mass arising from the posterior vaginal wall. Complete excision of the cyst was done. The cyst was filled with chocolate coloured material and histopathology confirmed a Mullerian cyst. [Int J Reprod Contracept Obstet Gynecol 2015; 4(1.000: 245-246

  18. Effects of lipopolysaccharide on the expression of proinflammatory cytokines and chemokines and the subsequent recruitment of immunocompetent cells in the oviduct of laying and molting hens.

    Science.gov (United States)

    Nii, T; Sonoda, Y; Isobe, N; Yoshimura, Y

    2011-10-01

    The goal of this study was to examine whether lipopolysaccharide (LPS) induces the expression of proinflammatory cytokines and chemokines and recruits T cells in the lower part of the oviduct, and whether that response to LPS is different between the laying and molting phase. White Leghorn laying and molting hens were intravenously injected with saline (control) or LPS. The uterus and vagina of oviducts were collected 3 or 6 h after injection, and used for reverse transcription PCR analysis of IL-1?, IL-6, IL-8 (CXCLi2), and lymphotactin (Lptn), and for immunohistochemical analysis for the frequency of CD4+ and CD8+ T cells. The expressions of IL-1?, IL-6, and CXCLi2 in the uterus and that of IL-1? in the vagina were upregulated in response to LPS 3 or 6 h after injection in both laying and molting hens. The CXCLi2 expression in the vagina was upregulated by LPS in laying hens, whereas those effects of LPS were not significant in molting hens. Expression of Lptn showed a tendency to be downregulated after 3 h, with recovery by 6 h after LPS injection. The frequency of CD4+ T cells tended to increase in response to LPS after 6 h in the lamina propria of the uterus and vagina in both laying and molting hens. The CD8+ T cell frequencies in the lamina propria of the uterus and vagina of laying hens increased in response to LPS after 6 h. However, in the molting hens, LPS stimulation resulted in CD8+ T cell increase in the vagina only and not in the uterus. These results suggest that expressions of proinflammatory cytokines and CXCLi2 chemokine are upregulated in association with T cell recruitment in response to LPS in the lower part of the oviduct, although CD8+ T cells in the uterus may be depressed during the molting phase. These immunoresponses may play roles in the defense against infection of the oviduct. PMID:21934017

  19. The impact of radiotherapy for carcinoma of the cervix on sexual function assessed using the LENT SOMA scales

    International Nuclear Information System (INIS)

    Background and purpose: As there are few studies examining the impact of radiotherapy on sexuality, we assessed the effect of radiotherapy for carcinoma of the cervix on sexual health and the ability of the LENT system to assess sexual function. Materials and methods: Using the vagina and sexual dysfunction scales of the LENT SOMA scales, subjective scores were measured prospectively before initiation of radiotherapy for 89 women, and at the following times after the start of treatment: 21, 70, 200, 400, 600 and 800 days. Results: There was considerable variation in pre-radiotherapy scores that was not related to disease stage (P=0.054), but was related to patient age (P=0.037, for the average vagina scores and P=0.039 for the maximum vagina scores) The scores were influenced by prior surgery (P<0.0005 for maximum and average vagina scores, P=0.042 average and 0.017 maximum sexual dysfunction scores). For 48 patients for whom data were available at the first three time points, the vagina scores decreased significantly by 70 days compared to pre-radiotherapy scores, but not for sexual dysfunction. There was heterogeneity in the pattern of changes of scores over time: for some women there was no change in vagina subsection score, some increased, and some decreased. Conclusions: The work has shown variation both in pre-treatment sexual function and in the pattern of changes seen following radiotherapy. Our questionnaire proved useful to score subjective sexual and vaginal problems as given in the LENT subjective scales. Further study is needed to assess the effectiveness of the scales in assessing late effects

  20. CONGENITAL VESICOUTERINE FISTULA ALONG WITH DISTAL VAGINAL AGENESIS, SOLITARY KIDNEY AND TONGUE TIE: A RARITY

    Directory of Open Access Journals (Sweden)

    Khalid

    2015-11-01

    Full Text Available : Congenital vesicouterine fistula in association with vaginal agenesis and solitary renal agenesis has been rarely reported. We present a case of 19 year old female suffering from cyclical menouria for last years. Physical examination revealed absence of vagina. IVP revealed left renal agenesis and CT scan revealed left renal agenesis with vesicouterine fistula. Cystoscopy showed vesicouterine fistula located above trigone near midline. Vesicouterine fistula was repaired along with uterine preservation. Sigmoid colon neovagina was created. Patient is doing well and menstruating per vagina till last followup

  1. Síndrome de Morris / Morris Syndrome

    Scientific Electronic Library Online (English)

    Julio Aurelio, Borrego López; Joel Alejandro, Varona Sánchez; Georgina, Areces Delgado; Luis Ernesto, Formoso Martín.

    2012-09-01

    Full Text Available Introducción: el síndrome de resistencia completa a los andrógenos, feminización testicular o síndrome de Morris, puede presentarse en uno de cada 20 000 a 64 000 recién nacidos varones. Objetivo: presentar un caso con genotipo masculino y fenotipo femenino dado por desarrollo mamario, con genitales [...] externos femeninos con hipoplasia de los labios mayores y menores y la vagina muy corta que termina en un fondo de saco ciego. Métodos: se valora en la consulta a una paciente adolescente de 19 años de edad con amenorrea primaria y contacto sexual insatisfactorio (imposibilidad de penetración). Resultados: se comprueba al examen vagina rudimentaria de unos dos centímetros y escaso desarrollo de genitales externos. En los exámenes complementarios se comprueban cifras de testosterona y LH aumentadas, así como el estradiol disminuido y un cariotipo 46 XY por lo que se sospecha síndrome de Morris y se planifica intervención quirúrgica combinada en un tiempo (vaginal y abdominal) donde se realiza anexectomía total derecha por video laparoscopia y reconstrucción de vagina por técnica de Williams. Posoperatorio satisfactorio y seguimiento ulterior por consulta donde se comprueba vagina funcional y estabilidad emocional de la paciente. Conclusiones: el estudio anatomo-patológico comprueba la existencia de ovario y testículo en la muestra quirúrgica lo que confirma el diagnóstico de síndrome de Morris o de resistencia completa a los andrógenos. Abstract in english Introduction:the syndrome of complete androgen resistance, testicular feminization or Morris syndrome may occur in one in 20 000 to 64 000 of male newborns. Objective: to present a case with male genotype and female phenotype given by breast development, female external genitalia with hypoplasia of [...] the labia and very short vagina ending in a blind pouch Methods: a 19 year- old female patient is assisted in consultation due primary amenorrhea and unsatisfactory sexual contact (impossibility of penetration). Results: at examination, we found a rudimentary vagina of about two inches and underdeveloped external genitalia. The exams confirmed increased LH and testosterone levels and decreased estradiol. It is also found a 46 XY karyotype, so Morris syndrome is suspected. Combined surgery is planned for the vagina and abdomen. Total videolaparoscopy right adnexectomy and vaginal reconstruction by technique of Williams are performed. We had satisfactory postoperative and subsequent follow-up consultation where functional vagina and emotional stability of the patient were checked. Conclusions: the pathological study verifies the existence of ovary and testis in the surgical specimen confirming the diagnosis of Morris syndrome or complete androgen resistance.

  2. Clear Cell Carcinoma Presented as a Large Polypoid Mass Expanding the Vaginal Fornix: Report of Two Cases

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Ji Young; Cho, Jae Ho [Dept. of Radiology, College of Medicine, Yeungnam University, Daegu (Korea, Republic of)

    2012-11-15

    Primary clear cell carcinoma of the vagina or uterine cervix is a very rare tumor. We report radiologic findings of two cases of clear cell carcinoma, arising in the vagina and uterine cervix in a 16-year-old and a 26-year-old female. These were presented as a large polypoid mass with a stalk and expanding the vaginal fornix. One case with ultrasonography showed relatively homogeneous echoic solid mass; the other case with a CT showed heterogeneously and strongly enhancing mass. All of the two cases showed non-specific signal intensity with heterogeneous and strong enhancement on MRI.

  3. Scientific Rationale and Algorithmization of Sochi Resort Natural and Preformed Physical Therapeutic Factors in the Course of Combined Treatment of Patients with Chronic Vulvovaginitis

    Directory of Open Access Journals (Sweden)

    Kirill V. Gordon

    2012-11-01

    Full Text Available Chronic vulvovaginitis is the most wide-spread gynecological pathology among women of childbearing age. The chief causations of nonspecific vulvovaginitis are reduction in oestrogen, disturbances in vaginal acidity, intestine dysbacteriosis, local and general immune disturbances. The growth of vagina opportunistic pathogenic flora is closely connected with the increase of bacterial slimes on vagina mucus. Sulphur balneotherapy in the form of general baths and vaginal irrigations, mechanical physiotherapy promotes disruption of bacterial slimes, oestrogen elevation, immune reconstruction and vaginal biocenosis, which has positive effect on patients’ fertility level, frequency of obstetrical and perinatal pathologies.

  4. Síndrome de Morris Morris Syndrome

    Directory of Open Access Journals (Sweden)

    Julio Aurelio Borrego López

    2012-09-01

    Full Text Available Introducción: el síndrome de resistencia completa a los andrógenos, feminización testicular o síndrome de Morris, puede presentarse en uno de cada 20 000 a 64 000 recién nacidos varones. Objetivo: presentar un caso con genotipo masculino y fenotipo femenino dado por desarrollo mamario, con genitales externos femeninos con hipoplasia de los labios mayores y menores y la vagina muy corta que termina en un fondo de saco ciego. Métodos: se valora en la consulta a una paciente adolescente de 19 años de edad con amenorrea primaria y contacto sexual insatisfactorio (imposibilidad de penetración. Resultados: se comprueba al examen vagina rudimentaria de unos dos centímetros y escaso desarrollo de genitales externos. En los exámenes complementarios se comprueban cifras de testosterona y LH aumentadas, así como el estradiol disminuido y un cariotipo 46 XY por lo que se sospecha síndrome de Morris y se planifica intervención quirúrgica combinada en un tiempo (vaginal y abdominal donde se realiza anexectomía total derecha por video laparoscopia y reconstrucción de vagina por técnica de Williams. Posoperatorio satisfactorio y seguimiento ulterior por consulta donde se comprueba vagina funcional y estabilidad emocional de la paciente. Conclusiones: el estudio anatomo-patológico comprueba la existencia de ovario y testículo en la muestra quirúrgica lo que confirma el diagnóstico de síndrome de Morris o de resistencia completa a los andrógenos.Introduction:the syndrome of complete androgen resistance, testicular feminization or Morris syndrome may occur in one in 20 000 to 64 000 of male newborns. Objective: to present a case with male genotype and female phenotype given by breast development, female external genitalia with hypoplasia of the labia and very short vagina ending in a blind pouch Methods: a 19 year- old female patient is assisted in consultation due primary amenorrhea and unsatisfactory sexual contact (impossibility of penetration. Results: at examination, we found a rudimentary vagina of about two inches and underdeveloped external genitalia. The exams confirmed increased LH and testosterone levels and decreased estradiol. It is also found a 46 XY karyotype, so Morris syndrome is suspected. Combined surgery is planned for the vagina and abdomen. Total videolaparoscopy right adnexectomy and vaginal reconstruction by technique of Williams are performed. We had satisfactory postoperative and subsequent follow-up consultation where functional vagina and emotional stability of the patient were checked. Conclusions: the pathological study verifies the existence of ovary and testis in the surgical specimen confirming the diagnosis of Morris syndrome or complete androgen resistance.

  5. Acesso sagital transretal anterior (ASTRA) para vaginoplastia após complicação de anoretoplastia sagital posterior / Anterior sagittal transrectal approach (ASTRA) for vaginoplasty after complications of posterior sagittal anorectoplasty

    Scientific Electronic Library Online (English)

    Lisieux Eyer de, Jesus; Laura, Helman; Samuel, Dekermacher; Raquel L., Bernardo; Cruz Delia M., Martinez.

    2013-06-01

    Full Text Available A exposição transperineal de altas vaginas é limitada. Essas limitações podem ser contornadas usando ASTRA (anterior sagital transrectal approach). Relatamos o uso desta estratégia cirúrgica para o tratamento de um caso de atresia vaginal adquirida, após anorretoplastia posterior, em caso de malform [...] ação anorretal. Abstract in english Transperineal exposure of the high portion of the vagina is limited. These limitations can be circumvented using ASTRA (anterior sagittal transrectal approach). We report the use of this surgical strategy for the treatment of a case of acquired vaginal atresia after posterior anorectoplasty due to a [...] norectal malformation.

  6. Rectovaginal Fistulae.

    Science.gov (United States)

    Das, Bidhan; Snyder, Michael

    2016-03-01

    Rectovaginal fistulae are abnormal epithelialized connections between the rectum and vagina. Fistulae from the anorectal region to the posterior vagina are truly best characterized as anovaginal or very low rectovaginal fistulae. True rectovaginal fistulae are less common and result from inflammatory bowel disease, trauma, or iatrogenic injury. A very few patients are asymptomatic, but the symptoms of rectovaginal fistula are incredibly distressing and unacceptable. Diagnostic approach, timing, and choice of surgical intervention, including sphincteroplasty, gracilis flaps, Martius flaps, and special circumstances are discussed. PMID:26929752

  7. Catheterization of the urethra in female pigs.

    Science.gov (United States)

    Musk, G C; Zwierzchoniewska, M; He, B

    2015-10-01

    Female pigs are commonly utilized as an animal model for biomedical research and require urethral catheterization. Sixteen pigs were anaesthetized for research purposes and required the placement of a urethral catheter. Post-mortem examination of the vaginas revealed the urethral opening to be consistently halfway from the mucocutaneous junction of the vulva to the cervix. A shallow diverticulum was also observed on the ventral floor of the urethral opening. To optimize conditions for success the pig should be carefully positioned supine, a vaginal speculum and light source should be used, the pig should be adequately anaesthetized, and the anatomy of the vagina should be reviewed. PMID:25977261

  8. Sexual Assault

    Science.gov (United States)

    ... legally give consent, such as when you are underage. The Department of Justice defines rape as "The penetration, no matter how slight, of the vagina or anus with any body part or object, or oral penetration by a sex organ of another person, without the consent of ...

  9. Childhood lichen sclerosus is a rare but important diagnosis

    DEFF Research Database (Denmark)

    Jensen, Lise Soldbro; Bygum, Anette

    2012-01-01

    Lichen sclerosus (LS) is a chronic skin disorder with a predilection for the anogenital area. The disease is mostly seen in prepubertal and postmenopausal females. The lesions present as sharply demarcated white plaques encircling the vagina and anus. The atrophic form can lead to scarring of the...

  10. Virulence Factors of Escherichia coli Isolated From Female Reproductive Tract Infections and Neonatal Sepsis

    OpenAIRE

    Hull, Richard A.; Hammill, Hunter A.; Cook, Susan W.

    2001-01-01

    Objective: The presence of enterobacteria such as Escherichia coli in the vagina of normal women is not synonymous with infection. However, vaginal E. coli may also cause symptomatic infections. We examined bacterial virulenceproperties that may promote symptomatic female reproductive tract infections (RTI) and neonatal sepsis.

  11. Biofeedback and physiotherapy versus physiotherapy alone in the treatment of genuine stress urinary incontinence

    DEFF Research Database (Denmark)

    Glavind, K; Nøhr, S B; Walter, S

    1996-01-01

    Biofeedback is a method of pelvic floor rehabilitation using a surface electrode inserted into the vagina and a catheter in the rectum. Forty women with genuine urinary stress incontinence were randomized to compare the efficacy of physiotherapy and physiotherapy in combination with biofeedback. ......-term effect in the biofeedback group seemed better and the patients were more motivated for training afterwards. Udgivelsesdato: 1996-null...

  12. Colostomía perineal en el carcinoma recto vaginal Perineal colostomy in recto-vaginal carcinoma

    Directory of Open Access Journals (Sweden)

    Elpidio Barrial García

    2005-03-01

    Full Text Available Se realizó una variante quirúrgica en una paciente con cáncer recto-vaginal, con infiltración del tercio inferior y cara lateral derecha del recto, muy próximo al esfínter del ano. La técnica consistió, previo diagnóstico por biopsia, en realizar excérecis del tumor que comprometió al parapeto derecho y el tercio inferior de vagina, terminando con una colostomía perineal, conservando algunas fibras del esfínter del ano. Se dejó drenaje en ambos lados y se reconstruyó resto de la vagina. Se logró buena continencia rectal del paciente, con buen estado de satisfacción. No hubo complicaciones y actualmente defeca sin dificultad. Ha tenido seguimiento por consulta de Oncoginecología del Hospital III Congreso de Pinar del Río. La intervención se llevó a cabo en una hora.A surgical alternative was performed in a patient suffering from rectovaginal cancer infiltrating the lower third and lateral right aspect of the rectum, so closed to anal sphincter. Operative technique consisted of a previous diagnosis by biopsy, besides, exceresis of the tumor that compromised right pararectum and lower third of vagina, ending in perineal colostomy preserving some fibers of anal sphincter. Drainage was performed in both sides and the rest of the vagina was reconstructed. A good rectal continence and well being were obtained, observing no complications, the patient defecates without difficulties, this case is followed up at "III Congreso Hospital" in Pinar del Rio. Operative procedures lasted an hour.

  13. Vaginal and cervical dilatation intrapartum is associated with eosinophilic infiltration in the cow but not in the sheep.

    Science.gov (United States)

    Wehrend, A; Gümbel, B; Leiser, R; Failing, K; Bostedt, H

    2004-12-01

    During parturition maximal dilatation of the vagina and cervix is necessary for expulsion of the neonate. The aim of the present study was to characterize the cell infiltration of the vagina and cervix that is associated with this event in cows and sheep. For this purpose, vaginal and cervical tissue were removed from four pluriparous cows and four sheep immediately after delivery of the neonate by biopsy under visual control (group 1), and the eosinophilic granulocytes were stained selectively. Four cows that were in interoestrus were used for control (group 2). In a third group of cows (n=10), blood samples were taken to determine the concentration of eosinophilic granulocytes from the fifth day antepartum up to the sixth day postpartum (group 3). A high degree of infiltration with eosinophilic granulocytes was detected in the bovine vagina and cervix intrapartum but not during interoestrus and in the ovine tissue intrapartum (p eosinopenia. In conclusion, this investigation demonstrates eosinophilic infiltration in the bovine vagina and cervix intrapartum, which differs from the situation in sheep. We suggest that this difference can be explained by the fact that cows deliver at high oestrogen and low progesterone values, but sheep show relatively high intrapartal P4 levels, which might suppress tissue infiltration with eosinophilic granulocytes. PMID:15598236

  14. Pyelonephritis and Bacteremia from Lactobacillus delbrueckii

    OpenAIRE

    Kevin M. DuPrey; Leon McCrea; Rabinowitch, Bonnie L.; Azad, Kamran N.

    2012-01-01

    Lactobacilli are normal colonizers of the oropharynx, gastrointestinal tract, and vagina. Infection is rare, but has been reported in individuals with predisposing conditions. Here we describe the case of a woman with pyelonephritis and bacteremia in which Lactobacillus delbrueckii was determined to be the causative agent.

  15. Urogenital tumors

    Energy Technology Data Exchange (ETDEWEB)

    Weller, R.E.

    1994-03-01

    An overview is provided for veterinary care of urogenital tumors in companion animals, especially the dog. Neoplasms discussed include tumors of the kidney, urinary bladder, prostate, testis, ovary, vagina, vulva and the canine transmissible venereal tumor. Topics addressed include description, diagnosis and treatment.

  16. Vaginal sponge and spermicides

    Science.gov (United States)

    ... suppositories. They are inserted into the vagina before sex. You can buy spermicides in most drug and grocery stores. Spermicides alone do not work very well. About 15 pregnancies occur out of every 100 women who correctly use this method alone over 1 ...

  17. Candidíase vulvovaginal: fatores predisponentes do hospedeiro e virulência das leveduras Vulvovaginal candidiasis: susceptibility factors of the host and virulence of the yeasts

    OpenAIRE

    Cassiana Aparecida Álvares; Terezinha Inez Estivalet Svidzinski; Márcia Edilaine Lopes Consolaro

    2007-01-01

    INTRODUÇÃO: Leveduras do gênero Candida são patógenos oportunistas freqüentemente isolados das superfícies mucosas de indivíduos normais, mas podem levar ao desenvolvimento de infecções denominadas candidíases, que variam desde lesões superficiais até infecções disseminadas. OBJETIVOS: Ampliar os conhecimentos sobre candidíase vulvovaginal (CVV: infecção de vulva e vagina, causada por leveduras comensais que habitam a mucosa vaginal) e candidíase vulvovaginal recorrente (CVVR: ocorrência de q...

  18. Genital Warts

    Science.gov (United States)

    Genital warts are a sexually transmitted disease (STD) caused by the human papillomavirus (HPV). The warts are soft, moist, pink, or flesh-colored bumps. ... or many of these bumps. In women, the warts usually occur in or around the vagina, on ...

  19. Robot-Assisted Gynecologic Oncology Surgery

    Medline Plus

    Full Text Available ... confined to the uterus at the time of diagnosis at the time of hysterectomy. So we always ... 04 CHRISTOPHER STANLEY, MD: I think specifically endometrial cancer, if the patient's ... pelvic sidewalls, to the bladder, to the lower vagina. If you can with ...

  20. Expression of C4.4A, a structural uPAR homolog, reflects squamous epithelial differentiation in the adult mouse and during embryogenesis

    DEFF Research Database (Denmark)

    Kriegbaum, Mette Camilla; Jacobsen, Benedikte; Hald, Andreas; Ploug, Michael

    2011-01-01

    , esophagus, non-glandular portion of the rodent stomach, anus, vagina, cornea, and skin. This epithelial confinement was particularly evident from the abrupt termination of C4.4A expression at the squamo-columnar transition zones found at the ano-rectal and utero-vaginal junctions, for example. During mouse...

  1. "You Want Me to Talk to Children about What?" Responding to the Subject of Sexuality Development in Young Children

    Science.gov (United States)

    Sciaraffa, Mary; Randolph, Theresa

    2011-01-01

    Many people think it is taboo to talk about sex with children. Adults reinforce this belief when, for example, they use substitute words rather than "vagina" or "penis". They may be embarrassed to learn about children's sexual development or ask others for assistance. Although most people in US society are open about sexuality now, the topic of…

  2. Condiloma Acuminado

    Directory of Open Access Journals (Sweden)

    Juan Carlos Céspedes Escobar

    2011-06-01

    Full Text Available El Condilomas Acuminado es una enfermedadcausada por el Virus Papiloma Humano.Se caracteriza por el crecimiento de verrugas blandas en los genitales o en la regiónanal, o sea que crece entre los muslos y la parte interna de las nalgas, en el pene o en la vagina.

  3. Scrotal perforation of peritoneal catheter: a rare complication of ventriculoperitoneal shunts

    OpenAIRE

    Saeidi Borojeni, Hamid Reza; Fakheri, Taravat; Saeidi Borojeni, Sepehr

    2012-01-01

    The standard treatment for the hydrocephalus is ventriculoperitoneal shunts (VPS) operation that diverts the excess accumulated cerebrospinal fluid (CSF) from the ventricles or other CSF containing spaces to another area. The VPS operation has been reportedly associated with risk factor for different organs due to peritoneal catheter migration including umbilicus, anus, vagina, mouth, intestine, internal jugular vein, chest, liver.

  4. Leukocyte esterase urine test

    Science.gov (United States)

    Leukocyte esterase is a urine test to look for white blood cells and other signs of infection. ... A clean-catch urine sample is preferred. The clean-catch method is used to prevent germs from the penis or vagina from getting ...

  5. The strange case of the misplaced suppository.

    OpenAIRE

    Richmond, C.

    1995-01-01

    In a controversial decision, the General Medical Council has found a consultant anesthetist guilty of serious professional misconduct for giving a painkilling suppository without forewarning the patient and obtaining consent. Even though the suppository was misplaced in the patient's vagina, this was accepted as a mistake, at issue was whether a specific separate consent was required for insertion of the suppository.

  6. Associations of Filaggrin Gene Loss-of-Function Variants and Human Papillomavirus-Related Cancer and PreCancer in Danish Adults

    DEFF Research Database (Denmark)

    Skaaby, Tea; Husemoen, Lise Lotte N; Jørgensen, Torben; Johansen, Jeanne D; Menné, Torkil; Szecsi, Pal B; Stender, Steen; Bager, Peter; Thyssen, Jacob P; Linneberg, Allan

    2014-01-01

    to human papillomavirus (HPV) infection and thus a higher risk of HPV-related cancer and pre-cancer. We investigated the association of the FLG genotype with incidence of HPV-related cancer of cervix, vagina, vulva, penis, anus and head and neck, and pre-cancer of the cervix. METHODS: We included 13...

  7. An unusual case of long standing vaginal foreign body removed with obstetric forceps

    Directory of Open Access Journals (Sweden)

    Padmalata

    2015-04-01

    Full Text Available This is a case of retained foreign body in vagina for 10 years, a wood apple which was inserted to reduce uterine prolapse. It was retained without any symptoms for 10 years. The foreign body was removed using obstetric forceps after other methods were failed. [Int J Reprod Contracept Obstet Gynecol 2015; 4(2.000: 502-504

  8. Sexual Problems

    Medline Plus

    Full Text Available ... into the vagina or as deep pain. Both psychological and physical factors can contribute to the condition. Current thinking is that dyspareunia is a pain disorder that interferes with sexuality, as ... to note that psychological problems such as sexual abuse can be involved ...

  9. Robot-Assisted Gynecologic Oncology Surgery

    Medline Plus

    Full Text Available ... 04 CHRISTOPHER STANLEY, MD: I think specifically endometrial cancer, if the patient's a surgical candidate, which means if the disease is limited to the uterus and not extended to the pelvic sidewalls, to the bladder, to the lower vagina. If you can with ...

  10. Oxytocin determination by radioimmunoassay in cattle. 2

    International Nuclear Information System (INIS)

    Oxytocin concentration in jugular vein blood was measured radioimmunologically with a detection limit of 3 pg/ml plasma in male and female cattle. Five bulls were tested; during mating a cow in oestrus with intromission and ejaculation, during mounting a dummy or another bull with ejaculation into an artificial vagina or during false mounts. No increase in oxytocin concentrations could be observed, but stimulation with an electro-ejaculator caused an increase ranging from 5-84 pg/ml after a latent period of 3-5 min. A similar response was observed in two cows following the same procedure. The contact with a bull, false mount or mating with intromission and ejaculation was not followed by a measurable oxytocin release in 5 test cows. The following stimulation techniques, massage of vulva and clitoris, massage of cervix and uterus per rectum, artificial insemination, introduction of a speculum into the vagina or insufflation of air into the vagina were performed with 5 cows and 5 heifers. Insufflation of air into the vagina was the most effective stimulus, eleciting an oxytocin release up to 588 pg/ml. All 5 heiers responded positively, as well as 4 cows in oestrus. The other manipulations cuased an oxytocin response mainly in heifers (whether in oestrus or dioestrus), whereas only one cow in oestrus responded with an oxytocin release. In general, oxytocin concentrations increase about 30-90 s after the start of the stimulus. (author)

  11. Healthy Sexuality

    Medline Plus

    Full Text Available ... body responds to sexual stimulation. During sexual arousal, blood flow increases to a woman’s genitals. Her vagina ... changes occur; a woman’s nipples become erect, her blood pressure and heart rate increase, and a “sex ...

  12. 21 CFR 884.3900 - Vaginal stent.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Vaginal stent. 884.3900 Section 884.3900 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES... stent. (a) Identification. A vaginal stent is a device used to enlarge the vagina by stretching, or...

  13. Robot-Assisted Gynecologic Surgery

    Medline Plus

    Full Text Available ... via the vagina, right? And that’s that little space there. That’s correct. That’s called a colpotomy, and ... the pelvis. This is not normally an empty space, it looks kind of like it because we ...

  14. Colposcopy - directed biopsy

    Science.gov (United States)

    ... care provider will place an instrument (called a speculum) into your vagina . This allows your doctor or ... You may have some discomfort when the speculum is placed inside the ... a regular Pap smear . Some women feel a slight sting from the ...

  15. 21 CFR 884.5920 - Vaginal insufflator.

    Science.gov (United States)

    2010-04-01

    ...insufflator is a device used to treat vaginitis by introducing medicated powder from a hand-held bulb into the vagina through an open speculum. (b) Classification. Class I. The device is exempt from the premarket notification procedures in subpart E of...

  16. Pap Smears

    Science.gov (United States)

    ... quickly. What Happens? The doctor will use a speculum to gently widen the vagina. A speculum is a thin piece of plastic or metal ... allows it to open and close. If the speculum is metal, the doctor or nurse will warm ...

  17. 21 CFR 884.4520 - Obstetric-gynecologic general manual instrument.

    Science.gov (United States)

    2010-04-01

    ...for obstetrical purposes. (2) A fiberoptic metal vaginal speculum is a metal instrument, with fiberoptic light, used to expose...illuminate the interior of the vagina. (3) A metal vaginal speculum is a metal instrument used to expose the interior of the...

  18. Your First Period

    Science.gov (United States)

    ... often should I change my tampon? What are menstrual cups? Does having a period cause pain or discomfort? What is amenorrhea? What if I ... are inserted into the vagina to catch the menstrual flow. You remove and empty the cup ... a period cause pain or discomfort? Some girls have a cramping pain ...

  19. CUERPO EXTRAÑO INTRAVAGINAL SECUNDARIO A MIGRACIÓN DE AGUJA DE OSTEOSÍNTESIS DE CADERA

    Directory of Open Access Journals (Sweden)

    Ernesto Perucca P

    2007-01-01

    Full Text Available Se presenta caso clínico de migración de aguja de fijación de artroplastia de cadera a vagina en mujer embarazadaWe report a case of an intravaginal foreign body due to migration of needle hip fixation from hip arthroplasty in a pregnant woman

  20. Oxytocin determination by radioimmunoassay in cattle. 2. Effect of mating and stimulation of the genital tract in bulls, cows and heifers

    Energy Technology Data Exchange (ETDEWEB)

    Schams, D.; Baumann, G. (Institut fuer Physiologie der Sueddeutschen Versuchs- und Forschungsanstalt fuer Milchwirtschaft der TU Muenchen); Leidl, W. (Gynaekologische und Ambulatorische Tierklinik der Universitaet Muenchen, Germany)

    1982-01-01

    Oxytocin concentration in jugular vein blood was measured radioimmunologically with a detection limit of 3 pg/ml plasma in male and female cattle. Five bulls were tested; during mating a cow in oestrus with intromission and ejaculation, during mounting a dummy or another bull with ejaculation into an artificial vagina or during false mounts. No increase in oxytocin concentrations could be observed, but stimulation with an electro-ejaculator caused an increase ranging from 5-84 pg/ml after a latent period of 3-5 min. A similar response was observed in two cows following the same procedure. The contact with a bull, false mount or mating with intromission and ejaculation was not followed by a measurable oxytocin release in 5 test cows. The following stimulation techniques, massage of vulva and clitoris, massage of cervix and uterus per rectum, artificial insemination, introduction of a speculum into the vagina or insufflation of air into the vagina were performed with 5 cows and 5 heifers. Insufflation of air into the vagina was the most effective stimulus, eleciting an oxytocin release up to 588 pg/ml. All 5 heiers responded positively, as well as 4 cows in oestrus. The other manipulations cuased an oxytocin response mainly in heifers (whether in oestrus or dioestrus), whereas only one cow in oestrus responded with an oxytocin release. In general, oxytocin concentrations increase about 30-90 s after the start of the stimulus.

  1. Surgical Tutorial of a Robotic-Assisted Anterior Pelvic Exenteration

    Medline Plus

    Full Text Available ... was found on evaluation here in the United States to have recurrence of her cervical cancer in the anterior portion of the cervix and the anterior vagina and it invading into the posterior bladder. To make matters a little more complicated, she was one of ...

  2. Ovulation Detection

    Science.gov (United States)

    ... org • URL www.asrm.org PATIENT’S FACT SHEET Ovulation Detection Ovulation, the release of an egg from its follicle ... into the woman’s vagina near the time of ovulation. The man’s sperm must be capable of swimming ...

  3. Genital injury

    Science.gov (United States)

    ... first aid. Control bleeding by using direct pressure. Place a clean cloth or sterile dressing on any open wounds. ... vagina is bleeding severely, put sterile gauze or clean cloths on ... sling made from towels. Place them on a padded cloth such as a ...

  4. Covered exstrophy with anorectal malformation and vaginal duplication

    Directory of Open Access Journals (Sweden)

    Bawa Monika

    2011-01-01

    Full Text Available Covered exstrophy is a rare variant of the exstrophy-epispadias complex. We report a female newborn with covered exstrophy, absent anal opening and duplication of the introitus and the lower vagina. This rare, previously unreported, combination of anomalies highlights the complexity of the embryological events in the caudal area during separation of the hindgut and allantois.

  5. Multikulturní dialog v Monologu o vaginach.

    Czech Academy of Sciences Publication Activity Database

    Uhde, Zuzana

    2005-01-01

    Ro?. 6, ?. 1 (2005), s. 39-40. ISSN 1213-0028 R&D Projects: GA AV ?R(CZ) 1QS700280503 Institutional research plan: CEZ:AV0Z70280505 Keywords : Vagina Monologues * gender justice * multiculturalism Subject RIV: AO - Sociology, Demography www.genderonline.cz

  6. Childhood lichen sclerosus is a rare but important diagnosis

    DEFF Research Database (Denmark)

    Jensen, Lise Soldbro; Bygum, Anette

    2012-01-01

    Lichen sclerosus (LS) is a chronic skin disorder with a predilection for the anogenital area. The disease is mostly seen in prepubertal and postmenopausal females. The lesions present as sharply demarcated white plaques encircling the vagina and anus. The atrophic form can lead to scarring of the affected area.

  7. Antimicrobial factors in the cervical mucus plug

    DEFF Research Database (Denmark)

    Hein, Merete; Valore, Erika V

    2002-01-01

    The cervical mucus plug is positioned between the microbe-rich vagina and the normally sterile uterine cavity, which suggests a host defense function, but few relevant data are available. We analyzed the composition and antimicrobial activity of cervical mucus plugs.

  8. Antenatal MR diagnosis of urinary hydrometrocolpos due to urogenital sinus

    Energy Technology Data Exchange (ETDEWEB)

    Subramanian, Subramanian; Sharma, Raju; Gamanagatti, Shivanand [All India Institute of Medical Sciences, Department of Radiodiagnosis, New Delhi (India); Agarwala, Sandeep [All India Institute of Medical Sciences, Department of Pediatric Surgery, New Delhi (India); Gupta, Prerna; Kumar, Sunesh [All India Institute of Medical Sciences, Department of Obstetrics and Gynaecology, New Delhi (India)

    2006-10-15

    Hydrometrocolpos is cystic dilatation of the vagina and uterus due to congenital vaginal obstruction. It may be secretory or urinary in character and manifests in the neonatal period with abdominal distension. Urinary hydrometrocolpos occurs in patients with urogenital sinus or cloacal anomaly. A rare case of antenatal MR diagnosis of urinary hydrometrocolpos due to urogenital sinus is presented. (orig.)

  9. Cervical Cancer

    Science.gov (United States)

    ... cancer is human papillomavirus (HPV) infection (see FAQ191 “Human Papillomavirus [HPV] Vaccination”). There are many types of HPV. Some types of HPV, called “high-risk types,” can cause cancer of the anus, cervix, vulva, vagina, and penis. They also can cause cancer of ...

  10. 75 FR 3745 - NIH Consensus Development Conference on Vaginal Birth After Cesarean: New Insights; Notice

    Science.gov (United States)

    2010-01-22

    ... HUMAN SERVICES National Institutes of Health NIH Consensus Development Conference on Vaginal Birth After... public. Vaginal birth after cesarean (VBAC) is the delivery of a baby through the vagina after a previous... Kennedy Shriver National Institute of Child Health and Human Development and the Office of...

  11. Successful pregnancy outcome in an untreated case of concomitant transverse complete vaginal septum with unicornuate uterus

    Directory of Open Access Journals (Sweden)

    Naina Kumar

    2014-01-01

    Full Text Available Transverse vaginal septum is a result of faulty canalization of embryonic vagina. Septum may be complete but usually has laterally placed tiny hole giving an impression of vaginal vault without cervix. We described a case of untreated transverse vaginal septum with small central aperture diagnosed during labor and unicornuate uterus diagnosed intraoperatively, with successful pregnancy outcome.

  12. 76 FR 70462 - Advisory Committee for Reproductive Health Drugs; Notice of Meeting

    Science.gov (United States)

    2011-11-14

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration Advisory Committee for Reproductive Health Drugs; Notice of... of pregnancy.'' The uterine cervix is the mouth of the uterus (or womb) leading into the vagina...

  13. Gonorrhea, Chlamydia, and Syphilis

    Science.gov (United States)

    ... of the uterus at the top of the vagina. Chancre: A sore caused by syphilis and appearing at the place of infection. Fallopian Tubes: Tubes through which an egg travels from the ovary to the uterus. Human Immunodeficiency Virus (HIV): A virus that attacks certain ...

  14. Primary Syphilis

    Science.gov (United States)

    ... Genital sites in women affected are the cervix, vagina, vulva, and clitoris. Cervical and vaginal syphilis infections may not be recognized. In men, the chancre is easily seen on the penis. Other locations of infection are limited only by human ingenuity and imagination. Common sites are around the ...

  15. Fungal Infections

    Science.gov (United States)

    ... form of candidal infection in and around the vagina. This is called a yeast infection. Pityriasis versicolor (say: pih-tuh-RYE-uh-sis VUR-suh-kul-ur) is a mouthful to say. It's a rash caused by a fungus that normally lives on human skin. It can appear over the chest, shoulders, ...

  16. Pregnancies from imipramine and xylazine-induced ex copula ejaculation in a disabled stallion.

    OpenAIRE

    Card, C E; Manning, S T; Bowman, P.; Leibel, T

    1997-01-01

    Breeding or semen collection was attempted using: natural cover, manual stimulation, artificial vagina, pharmacologic induction of ejaculation, and electroejaculation. Sperm cells were recovered from the ductus deferens and epididymides post mortem. Only semen collected ex copula by imipramine and xylazine treatment resulted in conceptions (4/5). This is the first report of pregnancies in horses from ex copula semen collection.

  17. Antenatal MR diagnosis of urinary hydrometrocolpos due to urogenital sinus

    International Nuclear Information System (INIS)

    Hydrometrocolpos is cystic dilatation of the vagina and uterus due to congenital vaginal obstruction. It may be secretory or urinary in character and manifests in the neonatal period with abdominal distension. Urinary hydrometrocolpos occurs in patients with urogenital sinus or cloacal anomaly. A rare case of antenatal MR diagnosis of urinary hydrometrocolpos due to urogenital sinus is presented. (orig.)

  18. Reducing Your Risk of Cancer

    Science.gov (United States)

    ... the Uterus) • Cervix (see the FAQ Cervical Cancer) • Vulva and vagina (see the FAQ Disorders of the Vulva) What are the warning signs of cancer? Most ... is shown in the FAQ Disorders of the Vulva. •Skin self-exam—Check your skin regularly to ...

  19. Syndrome in question

    Scientific Electronic Library Online (English)

    Yinhua, Wu; Jianjun, Qiao; Hong, Fang.

    2014-09-01

    Full Text Available Vulvovaginal-gingival syndrome is characterized by erosions and desquamation of the vulva, vagina, and gingiva. We reported a case of a 32-year-old woman presenting with an 8-year history of damage to the vulval and perianal anatomy and limitation of mouth opening. The patient's symptoms were reliev [...] ed after treatment with topical tacrolimus cream.

  20. Genital Herpes (For Parents)

    Science.gov (United States)

    ... Symptoms Symptoms of herpes outbreaks typically begin with pain, tenderness, or itching in the genital area and also might include fever and headache. Bumps and blisters may appear on the vagina, penis, scrotum, anus, thigh, or buttocks. Blisters soon open to form painful sores that ...

  1. Induction of mucin expression by estrogen and lipopolysaccharide in the lower oviductal segments in hens.

    Science.gov (United States)

    Ariyadi, B; Isobe, N; Yoshimura, Y

    2013-12-01

    Mucins play an essential role as mucosal barrier to prevent invasion of pathogens in the oviductal tissue of hens. The aim of this study was to determine the effect of estradiol and lipopolysaccharide (LPS) on the mucin expression in the lower oviductal segments (vagina and uterus) of hens. The mucosal tissues of the vagina and uterus were collected from White Leghorn laying and molting hens, and molting hens with or without intramuscular injection with 1 mg of estradiol-benzoate (EB) daily for 7 d. Part of these tissues was cultured in TCM-199 culture medium with or without LPS (10, 100, or 1,000 ng/mL) for 1.5 or 3 h. Mucin expression in the mucosa of laying, molting, and EB-treated molting hens (EB-group) and in those tissues cultured with or without LPS was analyzed by quantitative reverse-transcription PCR. Cultured tissues were also processed for paraffin sections and stained with Alcian blue (AB). In both the vagina and uterus, mucin expression and density of AB-positive mucopolysaccharide were reduced in molting hens compared with laying hens, and upregulated by EB. Mucin expression in the cultured vagina and uterus tissues of laying and molting hens was upregulated by LPS in a dose- and time-dependent manner. However, there was no response to LPS for induction of mucin in the tissues of EB-group hens. The mucin expression level in the vagina and uterus tissues stimulated by LPS was lower in the EB-group hens than in laying and molting hens, and that in the uterus was lower in the molting hens than in laying hens. These results suggest that mucin expression is stimulated by LPS in the vagina and uterus of laying and molting hens. Estrogen may upregulate mucin expression in those tissues in association with epithelial development, whereas it may suppress the response to LPS for mucin induction. The mucin expression caused by LPS may enhance mucosal barrier function and play a role in preventing infections by bacteria in the vagina and uterus. PMID:24235231

  2. The effect of semen collection method and level of egg yolk on capability of dilution and storage of buck semen

    Directory of Open Access Journals (Sweden)

    N.N. Dhaher

    2013-12-01

    Full Text Available The study was conducted to evaluate the effect of semen collection method for reduction of the deleterious interaction between the enzymes of bulbourethral gland and egg yolk during the dilution and storage of buck semen by three different level of egg yolk. Ten bucks were used in this study; the bucks were divided into two groups (five bucks in each group. Semen samples were collected once a week for four weeks from the bucks in first group using an artificial vagina, and from the animals in second group using an electroejaculator. The collected semen samples were diluted with sodium citrate extender with three different level of egg yolk (5, 10 and 20%. Extend semen samples were stored at 5 °C for three days. Computer assisted sperm analysis and Sperm Class Analyzer® were used for evaluation of the buck semen samples. Sperm motility parameters were evaluated which includes; percentage of motile sperm, percentage of progressive motile sperm, the value of the linear velocity (VSL, the value of the average velocity (VAP, the value of the curvilinear velocity (VCL, and the amplitude of lateral movement of the head (ALH. Results showed that all sperm motility parameters under the different level of egg yolk in semen samples that collected by artificial vagina were significantly higher than those which collected by electroejaculator. The percentage of motile sperm and progressive motile sperm of samples that collected by artificial vagina were higher at 10% of egg yolk, while these motility parameters were higher at 5% of egg yolk for semen samples that collected by electroejaculator. The differences between the two methods of semen collection in VCL and ALH were clear and the values were higher in samples that collected using the artificial vagina. The values of VSL, VAP and VCL of semen samples that collected by artificial vagina were higher at the second day than first day of semen storage under 10% of egg yolk. In conclusion, there are effects of the semen collection method on ability of dilution and storage of buck semen, and using of artificial vagina and 10% of egg yolk is recommended for buck semen dilution and storage.

  3. Hallazgo de una leucorrea vaginal de carácter no inflamatoria en hembras bovinas. I. Examen macroscópico y microscópico (Finding of a vaginal leucorrhea of non-inflammatory character in bovine females. I. Macroscopic and microscopic examination

    Directory of Open Access Journals (Sweden)

    Luis O. Alba Gómez,

    2005-10-01

    Full Text Available Con el objetivo de demostrar la existencia de una leucorrea vaginal no inflamatoria en hembras bovinas, se examinaron macroscópicamente los órganos genitales de 350 novillas y 800 vacas Cebú comercial y mestizas Holstein x Cebú sacrificadas en el matadero. Se colectaron secreciones leucorréicas en las vaginas o cuernos uterinos del 12 y 20% de las novillas y vacas respectivamente. Ninguno de los órganos genitales de estos animales mostraron signos de inflamación en sus mucosas. El examen histológico se realizó en 80 muestras de vagina y de cuernos uterinos leucorréicos y solamente el 6,3% de los cortes histológicos de vaginas y el 8,8% de los de úteros presentaron lesiones microscópicas leves. El pH vaginal promedió 6,85 ? 0,2. No se encontraron diferencias en el espectro electroforético entre las secreciones mucosas y las leucorréicas. Tampoco se encontraron células inflamatorias en los frotis teñidos. Los resultados indican que las secreciones leucorréicas observadas no son verdaderos exudados, sino secreciones mucosas modificadas que no tienen un origen inflamatorio. With the objective of demonstrating the existence of a non-inflammatory vaginal leucorrhea in bovine females, the genital organs of 350 heifers and 800 Zebu cows and of the crossing Holstein x Zebu, slaughterhouse, were examined macroscopically. Mucopurulent and purulent exudates were collected in vaginas or uterine horns of the 12 and 20% of heifers and cows respectively. In none of the genital organs of these animals were observed inflammation signs in their mucous membranes. For the histological examination 80 samples of those vagina and uterine horns were used; only 6.3% of the histological preparations from vagina and 8.8% from the uterus presented slight microscopic lesions. The vaginal pH averaged 6,85 ? 0,2. There were not differences in the electrophoretic spectrum between the mucous secretions and the leucorrheic one. Inflammatory cells in the stained vaginal smear were not found. The results point out that leucorrheic secretion observed are not true exudates, but modified mucous secretions, which have not an inflammatory origin. Key words: Bovine female. Vaginal exudate. Vaginal pH. Vaginal leucorrhea

  4. Morfologia e histologia do oviduto de marrecas Ana boschas / Morphology and histology of Ana Boschasfemale ducks oviduct

    Scientific Electronic Library Online (English)

    C., Moraes; S.M., Baraldi-Artoni; M.R., Pacheco; M., Nishizawa; L.S.O., Nakaghi.

    2010-04-01

    Full Text Available Avaliaram-se o comprimento do infundíbulo, do magno, do istmo, do útero e da vagina e o número de pregas do magno e do istmo do oviduto de 20 marrecas Ana boschas na fase reprodutiva. O infundíbulo apresenta mucosa com pregas longitudinais e baixas, revestidas por epitélio pseudoestratificado cilínd [...] rico ciliado, com células caliciformes. O magno, compartimento mais longo do oviduto, 25,38cm±3,20, encontra-se constituído por uma camada mucosa com pregas altas e espessas revestidas por células cilíndricas ciliadas e abundantes células caliciformes. O istmo é formado por uma mucosa com pregas estreitas e curtas e numerosas glândulas tubulares que se estendem para o interior da lâmina própria. O útero, região curta do oviduto, 5,25cm±1,26, apresenta parede com pregas e cristas baixas e numerosas glândulas tubulares enoveladas, dirigidas para o interior da lâmina própria. A vagina, um estreito tubo muscular, está constituído por oito anéis circulares, em média, e uma camada muscular altamente desenvolvida e espessa. A morfologia do oviduto da marreca apresenta características morfológicas e histológicas distintas dos galiniformes, observando-se que a vagina e a porção cranial do infundíbulo apresentam pregas e células caliciformes, respectivamente, sendo estas últimas estruturas ausentes nos galiniformes. Abstract in english The length of infundibulum, magnum, isthmus, uterus, vagina, and the number of oviduct, magnum, and isthmus folds were evaluated in 20 Ana boschas female ducks in the reproductive phase. The infundibulum presented mucous membrane with longitudinal and short folds, covered by ciliated columnar pseudo [...] stratified epithelium, with goblet cells. Magnum, the longest oviduct compartment, 25.38cm±3.20, is constituted by mucous membrane with high and thick folds that are covered by ciliated columnar cells and many goblet cells. Isthmus is formed by mucous membrane with narrow and short folds, and many tubular glands that extend inside lamina propria. Uterus, an oviduct short region, 5.25cm±1.26, presented surface with short folds and crests, and numerous reeled tubular glands, that are directed inside lamina propria. Vagina, a strait muscular tube, is constituted by, approximately, eight circular rings, and a very developed and thick muscular layer. The oviduct morphology of female ducks presented different morphological and histological characteristics from Galliformes, because vagina and infundibulum cranial portion present folds and goblet cells, respectively, and the last cited structures are absent in Galliformes.

  5. Actualización sobre vaginosis bacteriana

    Directory of Open Access Journals (Sweden)

    Wilmer Martínez Martínez

    2013-12-01

    Full Text Available La vaginosis bacteriana es una enfermedad polibacteriana que afecta a muchas mujeres en todo el mundo. La mayor prevalencia se observa en países subdesarrollados y en poblaciones con factores de riesgo como la promiscuidad. La enfermedad se produce cuando los lactobacilos, presentes en la microbiota normal de la vagina de mujeres sanas son reemplazados o superados en número por bacterias Gram negativas o Gram variables, anaerobias estrictas o facultativas presentes en pequeñas cantidades en la vagina sana y en el tracto gastrointestinal. La enfermedad puede cursar de forma asintomática o con leucorrea y ardor vulvar, en algunas pacientes puede ocasionar complicaciones obstétricas y ginecológicas importantes. El diagnóstico de la vaginosis bacteriana ha sido un tema controversial. Aunque existen algunos métodos diagnósticos clínicos y microbiológicos, todavía no se cuenta con un método potente para el diagnóstico eficaz de la vaginosis bacteriana.

  6. Amputação abdômino-perineal mais colostomia para-vaginal no tratamento do câncer reto-anal Abdomino-perineal amputation plus para-vaginal colostomy in the treatment of reto-anal cancer

    Directory of Open Access Journals (Sweden)

    Alcino Lázaro da Silva

    2009-12-01

    Full Text Available O apresenta uma proposta e as tentativas iniciais para evitar a colostomia abdominal quando esta tem que ser definitiva. Na mulher foi possível a sua execução, desde que se aproveitou o tono da musculatura esfincteral vulvovaginal quando ela pode ser preservada na amputação de reto-ânus. O colo, preparado com as válvulas, desce posteriormente à vagina, por dentro do conjunto esfincteral vulvovaginal. As observações iniciais mostram que esta tentativa poderia ser incrementada para melhores estudos de continência.The Author presents a proposal and lhe initial attempties to avoid the abdominal colostomy when it has to be definitive. In the woman was possible its execution, since it took advantage from the vulvovaginal esfincteral muscle nohen it can be preserved ot the anus-rectum amputation. The colon, prepared wit the valves, descend posteriorily from the vagina, inside the vulvo-vaginal esfincteral group. The initial observations shows that this attempt could be better developed for cotinency etudies.

  7. Successful Delivery of Twin Pregnancy in Class U3b/C2/V1 Uterus by Bilateral Caesarean Section after Spontaneous Conception

    Science.gov (United States)

    El-Masry, Yasmine; Ossman, Ahmed M. E.; El-Namoury, Mohammed; Sarsik, Sameh

    2015-01-01

    A case of a 19-year-old female with class U3b/C2/V1 uterus conceived a twin pregnancy with a fetus in each horn after spontaneous conception. She referred to our department with presentation of premature rupture of membranes, with a history of cesarean delivery of a single full term living fetus a year and a half before this delivery. Examination revealed two completely separate uterine horns with a fetus in each horn, two distinct externally rounded cervices, and a single vagina with a short nonobstructing vaginal septum in the upper part of the vagina. And as the appropriate mode of delivery is still unclear, each case should be managed as the condition requires, and in our case urgent bilateral caesarean sections were performed. PMID:26557398

  8. Effect of certain yogic asanas on the pelvic congestion and it's anatomy.

    Science.gov (United States)

    Mishra, S P; Singh, R H

    1984-10-01

    20 patient including 6 females and 14 males, between 20 years to 30 years of age, with complaints of chronic constipation refractory to various treatments by medicines, belching, sense of heaviness in the lower abdomen or pelvic region, offensive discharge from vagina (leucorrhoea) and bleeding per rectum with discomfort in the region of perineum were observed under instructions and supervision to practice certain yogic exercises for a period of three years. Viparitakarani, Goraksa asana, Uddyana Bandha and Mula Bandha (Nauli, Perineal Shrug) when practiced, relieved these patients were asked not to take any purgatives or laxatives. It was concluded from the present study that these complaints which can be ascribed to poor hemodynamics in the region of pelvis and perineum disappeared and patients showed obvious improvement after practicing these Asanas which reduced pelvic congestion and increased blood flow to the pelvic viscera i.e rectum, anal canal, prostate, uterus, vagina and levator ani and perineal muscles. PMID:22557465

  9. MR-colpocystorectography. A new dynamic method for assessing pelvic floor descent and prolapse in women

    International Nuclear Information System (INIS)

    Introduction of a new method for the dynamic evaluation of genital prolapse by using fast magnetic resonance imaging. Dynamic fast magnetic resonance imaging with pelvic floor contraction, relaxation and straining manoeuvres were performed with volunteers and patients presenting with pelvic descent. The urethra, bladder, vagina and rectum were opacified by using a water of MagnevistR enteral solution. Delineation and movement of the urethra, bladder, uterus, vagina, rectum and small bowel can be shown in a reliable manner. In comparison to dynamic fluoroscopy an equal or superior diagnosis has been achieved in all cases. In comparison to dynamic fluoroscopy MR-Colpocystorectography is a promising new method in assessing pelvic floor descent and prolapse in women. Further studies will have to focus on standardisation and clinical implication. (orig.)

  10. Complete imperforate tranverse vaginal septum with septate uterus: A rare anomaly

    Directory of Open Access Journals (Sweden)

    Nutan Jain

    2013-01-01

    Full Text Available The isolated, complete, transverse vaginal septum is one of the most infrequent anomalies of the female genital tract, and when it coexists with a septate uterus, it is even rarer. This report describes a case of transverse vaginal septum with septate uterus. A 12-year-old girl sought medical assessment because of severe cyclic lower abdominal cramping and pelvic pain. Local examination revealed a blind vaginal pouch of 2 cm and on rectal examination a tender pelvic mass was noted. Radiological examination showed transverse vaginal septum in the lower vagina with bicornuate uterus. Surgical resection of the vaginal septum was done under laparoscopic guidance. Hysteroscopy revealed presence of uterine septum which was resected by a resectoscope. Post-operative dilatation of vagina was done to prevent restenosis. Laparoscopic guided abdominoperineal approach is better in such a case as multiple mullerian anomalies may coexist with each other.

  11. [Colonization with group B streptococcus in pregnant women taken into the care of unit K and hospitalized in the department of obstetric pathology].

    Science.gov (United States)

    Szponar, M; Gali?ski, J; Bolt, L; Ordyniec, E

    1992-01-01

    Colonization with group B streptococci (GBS) in 714 pregnant women was investigated. Among 232 were hospitalised in department of pathological pregnancy and 512 were under ambulatory control. In 13.4% of hospitalised patients and 2.8% healthy pregnant women the colonization of vagina or throat with GBS was stated. The greatest percentage of vagina colonization was found in patients hospitalised in connection with gestosis or because of abortions, premature delivery and inanimate fetus. No correlation was found between range of GBS colonization and trimester of pregnancy. Almost all GBS strains proved to be susceptible for commonly used antibiotics but resistant to biseptol (88.2%). Patients of hospitalised group were more often colonized not only GBS but also other potentially pathogenic microorganisms. PMID:1304502

  12. AIDS-related Kaposi sarcoma: findings on thallium-201 scintigraphy

    International Nuclear Information System (INIS)

    No simple, noninvasive method is available for evaluating extracutaneous Kaposi sarcoma in AIDS patients or for following the tumor's response to treatment. We report our preliminary experience with thallium-201 scintigraphy in nine AIDS patients with proved Kaposi sarcoma. Eight of the nine had abnormal uptake of the radionuclide in skin, lymph nodes, oral cavity, vagina, and lungs. Only four of the nine had cutaneous Kaposi sarcoma at the time of scanning. All cutaneous and mucosal lesions were thallium avid. Two of the six patients with thallium-avid nodes underwent nodal biopsy. Both biopsies confirmed the diagnosis of Kaposi sarcoma. Cutaneous Kaposi sarcoma developed later in one of these patients, showing the efficacy of thallium scintigraphy for the early detection of extracutaneous lesions. These preliminary results show thallium avidity in Kaposi sarcoma involving the skin and various extracutaneous sites (lymph nodes, lung, mucosa, and vagina). Thallium scintigraphy is a potentially useful procedure for detecting extracutaneous Kaposi sarcoma in AIDS patients

  13. Studies and methodologies on vaginal drug permeation.

    Science.gov (United States)

    Machado, Rita Monteiro; Palmeira-de-Oliveira, Ana; Gaspar, Carlos; Martinez-de-Oliveira, José; Palmeira-de-Oliveira, Rita

    2015-09-15

    The vagina stands as an important alternative to the oral route for those systemic drugs that are poorly absorbed orally or are rapidly metabolized by the liver. Drug permeation through the vaginal tissue can be estimated by using in vitro, ex vivo and in vivo models. The latter ones, although more realistic, assume ethical and biological limitations due to animal handling. Therefore, in vitro and ex vivo models have been developed to predict drug absorption through the vagina while allowing for simultaneous toxicity and pathogenesis studies. This review focuses on available methodologies to study vaginal drug permeation discussing their advantages and drawbacks. The technical complexity, costs and the ethical issues of an available model, along with its accuracy and reproducibility will determine if it is valid and applicable. Therefore every model shall be evaluated, validated and standardized in order to allow for extrapolations and results presumption, and so improving vaginal drug research and stressing its benefits. PMID:25689736

  14. Natural orifice transluminal endoscopic surgery: The transvaginal route moving forward from cholecystectomy

    Directory of Open Access Journals (Sweden)

    Eduardo M Targarona

    2010-06-01

    Full Text Available The advent of minimally invasive surgery and the advances in endoluminal flexible endoscopy have converged to generate a new concept in digestive surgery, whose acronym natural orifice transluminal endoscopic surgery (NOTES, has become a familiar term in the surgical community. NOTES has been performed through the mouth, the bladder, the rectum and the vagina. Of these four approaches, the vagina has gained most popularity for several reasons. It is not only readily accessible and easy to decontaminate but it also provides safe entry and simple closure. The transvaginal approach has been described in the experimental and the clinical setting as an option for cholecystectomy, nephrectomy, splenectomy, segmental gastrectomy, retroperitoneal exploration and bariatric surgery. However, larger series are needed to delineate the exact risks of this approach, and to transcend cultural barriers that impede its wider introduction. Prospective randomized trials will shed light on the definitive role of the vaginal approach in minimal invasive surgery of the future.

  15. The McKusick-Kaufman hydrometrocolpos-polydactyly syndrome: A rare case report

    Directory of Open Access Journals (Sweden)

    Swapnil P Yewalkar

    2013-01-01

    Full Text Available A combination of hydrometrocolpos, polydactyly, and cardiac anomlies is the cardinal feature of McKusick-Kaufman syndrome. Neonatal hydrometrocolpos is rare Mullerian duct anomaly caused by obstruction of the vagina. There is an accumulation of mucus secretions proximal to the obstruction. The secretions are secondary to intrauterine and postnatal stimulation of uterine and cervical glands by maternal estrogens. Here, we report a case of 1-day-old neonate who presented with abdominal distension. Ultrasound and computed tomography findings revealed a large abdominopelvic cystic mass posterior to the urinary bladder. Other associated findings were polydactyly and bilateral hydronephosis. Laparotomy confirmed the findings of hydrometrocolpos caused by stenosis/atresia of lower vagina.

  16. FORMULATION, EVALUATION AND MICROBIAL ASSAY OF TINIDAZOLE VAGINAL SUPPOSITORY CONTAINING LACTIC ACID BACILLUS SPORES

    Directory of Open Access Journals (Sweden)

    SC Shivhare*, AR Umarkar and PA Salunke

    2014-07-01

    Full Text Available Human vagina represents a dynamic ecosystem dominated by certain species of Lactobacillus. This microorganism restricts the growth of pathogens by using properties of steric exclusion and inhibitory substance production. Serious complications including bacterial vaginosis and vaginal cancer are often determined in women with reduced numbers of lactobacilli. Local application of Lactobacillus is consequently promising to keep the vagina colonized by this strain, which consequently reduces the infections. The first objective of this research was to develop a local application pharmaceutical formulation of a vaginal suppository containing lyophilized culture of Lactobacillus with anti-microbial agent tinidazole. The second objective was to establish its in vivo performance by developing in vitro methods of evaluation as well as antimicrobial activity of tinidazole alone with Lactic acid Bacillus Spores in vaginosis.

  17. Custom fabricated acrylic vaginal stent as an adjunct to surgical creation of neovagina for a young female with isolated vaginal agenesis

    Directory of Open Access Journals (Sweden)

    Manu Rathee

    2014-01-01

    Full Text Available Vaginal agenesis is one of the major congenital anomalies of the female genital tract. It may present either as an isolated developmental defect or within a complex of more extensive anomalies. Most commonly it is associated with Mayer-Rokitansky-K?ster-Hauser (MRKH syndrome. The correction of vaginal agenesis requires the creation of a neovaginal cavity that is dissected between the bladder and the rectum. After reconstruction of space for vagina surgically, a long-term vaginal stent use is required to maintain vaginal width and depth and to prevent contraction. In this article is presented a case of nonsyndromic agenesis of vagina in a 14-year-old girl and its surgical management using custom fabricated acrylic vaginal stent.

  18. A study on congenital vaginal malformations in rural population of north Maharashtra region

    OpenAIRE

    Sarita Ajit Deshpande, Ajit Balkrishna Deshpande

    2013-01-01

    To find out types of vaginal malformations in rural population of North Maharashtra, to study various operative procedures designed for vaginal malformations and to evaluate the use of rubber mould for McIndoe operation. Method: Eighteen cases of congenital vaginal malformations were screened in OPD. We found seventeen patients of primary amenorrhea were having congenital vaginal malformation. One patient of stricture of upper vagina was having normal menstruation. They were investigated acco...

  19. Oral microflora in infants delivered vaginally and by caesarean section

    DEFF Research Database (Denmark)

    Nelun Barfod, Mette; Magnusson, Kerstin; Lexner, Michala Oron; Blomqvist, Susanne; Dahlén, Gunnar; Twetman, Svante

    2011-01-01

    International Journal of Paediatric Dentistry 2011 Background. Early in life, vaginally delivered infants exhibit a different composition of the gut flora compared with infants delivered by caesarean section (C-section); however, it is unclear whether this also applies to the oral cavity. Aim. To investigate and compare the oral microbial profile between infants delivered vaginally and by C-section. Design. This is a cross-sectional case-control study. Eighty-four infants delivered either vagina...

  20. Adherence of group B streptococci to cultured epithelial cells: roles of environmental factors and bacterial surface components.

    OpenAIRE

    Tamura, G S; Kuypers, J M; Smith, S.; Raff, H.; Rubens, C.E.

    1994-01-01

    Group B streptococci (GBS) are the major cause of neonatal pneumonia, sepsis, and meningitis. Steps considered to be important in the pathogenesis of this infection include colonization of the rectum and vagina of the mother, aspiration of GBS into the fetal lung during or just prior to delivery, and invasion of GBS into pulmonary epithelial cells. We have previously demonstrated that GBS can invade pulmonary epithelial cells both in vivo and in vitro. Adherence of GBS to epithelial cells may...

  1. 148?HPV, HIV, and Cancer: A Global Challenge

    OpenAIRE

    Franceschi, Silvia

    2014-01-01

    The seminal discovery that human papillomavirus (HPV) infection causes cervical cancer provides an opportunity for prevention by vaccination and new screening approaches. Approximately 600,000 new cancer cases per year are attributable to HPV worldwide of which about half million in less developed countries (de Martel et al, Lancet Oncology, 2012). These cancers include all cervical cancers, the vast majority of anal cancers and approximately half of cancers of the vulva, vagina, and penis. I...

  2. Colonization Rate of Group B Streptococcus (GBS) in Pregnant Women Using GBS Agar Medium

    OpenAIRE

    Fatemi F; Chamani L; Pakzad P; Zeraati H; Rabbani H; Asgari S

    2009-01-01

    Group B streptococci (GBS) or Streptococcus agalactiae are members of the normal flora of the female genital tract. GBS normally colonizes the vagina in many women asymptomatically. During labor this organism may infect the newborn, leading to neonatal sepsis and meningitis. This study aimed to investigate the prevalence of group B streptococcus in pregnant women by a rapid and easy culture method. It seems that in cases in which GBS carriage is not suspected until the time of labor, using su...

  3. Amputação abdômino-perineal mais colostomia para-vaginal no tratamento do câncer reto-anal Abdomino-perineal amputation plus para-vaginal colostomy in the treatment of reto-anal cancer

    OpenAIRE

    Alcino Lázaro da Silva

    2009-01-01

    O apresenta uma proposta e as tentativas iniciais para evitar a colostomia abdominal quando esta tem que ser definitiva. Na mulher foi possível a sua execução, desde que se aproveitou o tono da musculatura esfincteral vulvovaginal quando ela pode ser preservada na amputação de reto-ânus. O colo, preparado com as válvulas, desce posteriormente à vagina, por dentro do conjunto esfincteral vulvovaginal. As observações iniciais mostram que esta tentativa poderia ser incrementada para melhores est...

  4. Correlates of Occurrence of Obstetric Fistula among Women in Selected States of India: An Analysis of DLHS1-3 Data

    OpenAIRE

    Gulati, B.K.; Unisa, S.; Pandey, A.; Sahu, D; Ganguly, S.

    2011-01-01

    Obstetric fistula is the most devastating form of maternal morbidity. It is an opening in the wall of vagina connecting to bladder or to rectum due to prolonged obstructed labour without timely medical assistance. A few research studies carried out in India and recently conducted DLHS-3 survey (2007-08) has information on obstetric fistula that gives scope for further research. This paper examines prevalence of obstetric fistula and its correlates using DLHS-3 data for selected states in Indi...

  5. Genetic basis of semen traits and their relationship with growth rate in rabbits

    OpenAIRE

    Tusell, Llibertat; Legarra, Andres; Garcia-Tomas, M.; Rafel, O.; Ramon, J.; Piles, M.

    2012-01-01

    This work aims to estimate the genetic parameters of seminal and production traits in a paternal line of rabbits selected for ADG during the fattening period. The onsidered traits were male libido (Lib) defi ned as successful mounting of an artificial vagina; presence of urine (Ur) and calcium carbonate deposits (Ca) in the ejaculate; semen pH; individual sperm motility (IM); the suitability for AI of the ejaculate (Sui), which involves the subjective combination of several quality traits; th...

  6. Social and health reasons for lime juice vaginal douching among female sex workers in Borno State, Nigeria

    OpenAIRE

    Abdulkarim G. Mairiga; Kullima, Abubakar A.; Kawuwa, Mohammed B.

    2010-01-01

    Background: Vaginal douching with lime juice and other agents has been perceived to enhance sexual excitement through sensations of vaginal dryness, tightness or warmth, as well as prevent sexually transmitted infections and restore and tighten the vagina after delivery. Its effectiveness as a contraceptive has also been reported. However, the social and health reasons/consequences of such a practice have not been adequately documented in the communities of Borno State, Nigeria.Objectives: Th...

  7. Pulmonary Aplasia with Unusual Associations in a Woman

    OpenAIRE

    Bachh, Arshad Altaf; Pulluri, Sridhar; Beigh, Aadil; Raju, Chippa; Deshpande, Ranganath

    2014-01-01

    Failure of development of the primitive lung bud leads to an extremely rare congenital anomaly with a prevalence of 34 per 10 lac live births termed pulmonary aplasia. In half of such cases, associated congenital malformations of the cardiovascular, skeletal, gastrointestinal, or genitourinary systems are present. The Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is defined as the congenital aplasia of the uterus and the upper two thirds of the vagina with normal secondary sexual characteris...

  8. Evaluation of degradation kinetics and physicochemical stability of tenofovir

    OpenAIRE

    Agrahari, Vivek; Putty, Sandeep; Mathes, Christiane; Murowchick, James B; Youan, Bi-Botti C.

    2014-01-01

    Tenofovir (TFV) has been proven to prevent the transmission of the Human Immunodeficiency Virus (HIV) through the vagina. But, there is little information available about its stability under various storage and stress conditions. Hence, this study aimed to investigate the degradation behavior and physicochemical stability of TFV using liquid chromatography coupled mass spectrometry (LC-MS) and solid state X-ray diffraction (XRD) analyses. The LC-MS analysis was performed on a QTrap mass spect...

  9. Social and health reasons for lime juice vaginal douching among female sex workers in Borno State, Nigeria

    OpenAIRE

    Kullima, Abubakar A.; Abdulkarim G. Mairiga; Mohammed B. Kawuwa

    2010-01-01

    Background: Vaginal douching with lime juice and other agents has been perceived to enhance sexual excitement through sensations of vaginal dryness, tightness or warmth, as well as prevent sexually transmitted infections and restore and tighten the vagina after delivery. Its effectiveness as a contraceptive has also been reported. However, the social and health reasons/consequences of such a practice have not been adequately documented in the communities of Borno ...

  10. Vaginal cancer with multiple liver and pulmonary metastases that achieved long-term survival

    OpenAIRE

    Kim, Ji-young; Lee, Kyoung-A; Kim, Byoung-Gie; Bae, Duk-Soo; Lee, Jeong-Won

    2013-01-01

    Primary vaginal cancer represents only 1% to 2% of malignant neoplasm of the female genital tract. Here, we report a 68-year-old woman who showed a vaginal tumor extending to urethra and clitoris, a 10 cm-sized mass in left adnexa and multiple metastases in lung and liver. Vaginal biopsy showed squamous cell carcinoma of vagina and she was diagnosed as International Federation of Gynecology and Obstetrics stage IVB vaginal cancer. Palliative surgery including left salpingectomy, tumorectomy, ...

  11. A Case of Vaginal Cancer with Uterine Prolapse

    OpenAIRE

    Kim, Hwi-Gon; Song, Yong Jung; Na, Yong Jin; Choi, Ook-Hwan

    2013-01-01

    Primary vaginal cancer combined with uterine prolapse is very rare. We present a case of 80-year-old postmenopausal women complaints of something coming out per vagina for the past 20 years, along with blood stained discharge, foul odor leukorrhea, and severe pelvic pain for the last 3 months. A 4 × 5 cm ulcer was present on middle third of vaginal wall with marked edema and ulceration of surrounding tissue. The prolapse was reduced under intravenous sedation in operating room. On gynecologic...

  12. Understanding vaginal microbiome complexity from an ecological perspective

    OpenAIRE

    Hickey, Roxana J; Xia ZHOU; Pierson, Jacob D.; Ravel, Jacques; Forney, Larry J.

    2012-01-01

    The various microbiota normally associated with the human body have an important influence on human development, physiology, immunity, and nutrition. This is certainly true for the vagina wherein communities of mutualistic bacteria constitute the first line of defense for the host by excluding invasive, nonindigenous organisms that may cause disease. In recent years much has been learned about the bacterial species composition of these communities and how they differ between individuals of di...

  13. DUCHAS VAGINALES Y OTROS RIESGOS DE VAGINOSIS BACTERIANA

    OpenAIRE

    Chávez, Natividad; Molina, Helfer; Sánchez, Jorge; Gelaye, Bizu; Sánchez, Sixto E

    2009-01-01

    Vaginosis bacteriana (VB) es una infección caracterizada por el cambio en la microflora de la vagina, asociándose a resultados adversos del embarazo y a la adquisición de infecciones de transmisión sexual (ITS), incluyendo el VIH. En este estudio se buscó la asociación entre el uso de duchas vaginales y otros factores de riesgos con VB.

  14. Cesarean section and right femur fracture: a rare but possible complication for breech presentation

    OpenAIRE

    Giampiero Capobianco; Giuseppe Virdis; Pietro Lisai; Claudio Cherchi; Ornella Biasetti; Francesco Dessole; Giovanni Battista Meloni

    2013-01-01

    Background. The breech extraction of the fetus through the vagina has a greater risk of hip fracture compared with the extraction by abdominal route. Case. A 2390 g female infant was delivered at 39 weeks by elective cesarean section for breech presentation. The newborn sustained a fracture of the right femur. A simple immobilization of the limb in extension led to a complete healing of the fracture without sequelae. Conclusion. Caesarean delivery reduces the risk of causing a traumatic injur...

  15. Is breech still being delivered vaginally? A comparative study

    OpenAIRE

    Saira Dars; Safia Malik; Aijaz Bhurgri

    2014-01-01

    Background: This study aimed to find out the frequency of singleton term breech presentation and to complete the fetomaternal outcome between spontaneous vaginal and caesarean delivery. We conducted an observational prospective study to describe neonatal outcome of vagina verses cesarean delivery for term breech presentation. Methods: The study was conducted in department of Gynae and Obs. Unit-1, LUMHS, Jamshoro from 1st January 2011 to 31st December 2012. All those pregnant women who wer...

  16. Anti-Adhesion Activity of A2-type Proanthocyanidins (a Cranberry Major Component) on Uropathogenic E. coli and P. mirabilis Strains

    OpenAIRE

    Daria Nicolosi; Gianna Tempera; Carlo Genovese; Furneri, Pio M.

    2014-01-01

    Urinary tract infections (UTIs) are relatively common in women and may be classified as uncomplicated or complicated, depending upon the urinary tract anatomy and physiology. Acute uncomplicated cystitis (AUC) occurs when urinary pathogens from the bowel or vagina colonize the periurethral mucosa and reach the bladder. The vast majority of episodes in healthy women involving the same bacterial strain that caused the initial infection are thought to be reinfections. About 90% of AUC are caused...

  17. Advances in labor analgesia

    OpenAIRE

    Wong, Cynthia A.

    2009-01-01

    Cynthia A WongDepartment of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USAAbstract: The pain of childbirth is arguably the most severe pain most women will endure in their lifetimes. The pain of the early first stage of labor arises from dilation of the lower uterine segment and cervix. Pain from the late first stage and second stage of labor arises from descent of the fetus in the birth canal, resulting in distension and tearing of tissues in the vagina...

  18. Intrapartum ultrasound: A useful method for evaluating labor progress and predicting operative vaginal delivery

    OpenAIRE

    Ahn, Ki Hoon; Oh, Min-Jeong

    2014-01-01

    The last step of a successful pregnancy is the safe delivery of the fetus. An important question is if the delivery should vaginal or operative. In addition to the use of conventional antenatal ultrasound, the use of intrapartum ultrasound to evaluate fetal head station, position, cervical ripening, and placental separation is promising. This review evaluates and summarizes the usefulness of intrapartum ultrasound for the evaluation of labor progress and predicting successful operative vagina...

  19. Evaluation of the rapid Patho Dx Latex Strep Grouping Kit.

    OpenAIRE

    Beck, R.; Etzion, R; Sandler, S.; Kohn, L.

    1990-01-01

    A variety of clinical specimens from throat, nose, ear, eye, wounds, urine, and vagina were collected, cultured, and screened for beta-hemolytic streptococci. The Patho Dx Latex Strep Grouping Kit (Diagnostic Product Corp., Los Angeles, Calif.) technique was applied to colonies taken right from the primary cultures. Isolated strains were sent to the reference laboratory where they were grouped by standard techniques. The kappa coefficient of agreement between the Patho Dx Kit and the standard...

  20. WOMEN FACING HEAVY VAGINAL DISCHARGE (LEUCORRHEA) BY VIRTUE OF UNHEALTHY LIFE STYLE

    OpenAIRE

    Somia Gul; Hina Qamar; Wardha Jawaid; Urooj Bukhari; Yumna Javed

    2013-01-01

    Leucorrhea also spelled leucorrhoea, flow of a whitish, yellowish, or greenish discharge from the vagina of the female that may be normal or that may be a sign of infection. It is mucous discharge which represents desquamation of vaginal epithelial cells because of the effects of estrogen on the vaginal mucosa. It is important to distinguish leucorrhea from pathologic discharge. Leucorrhea usually does not cause irritation but some adolescents worry that it may represent an infection. A total...

  1. Case of Urethral Foreign Body: IUD Perforation of the Bladder with Calculus Formation

    OpenAIRE

    Gillis, Erin; Chhiv, Nak; Kang, Sacha; Sayegh, Rocky; Lotfipour, Shahram

    2006-01-01

    A 28-year-old female presented to the Emergency Department (ED) with a chief complaint of strings protruding from her vagina. The patient also complained of recurrent symptoms of cystitis and occasional hematuria over the past five months without resolution after treatment. The patient underwent ED evaluation and was noted to have strings coated in calculus protruding from her urethral meatus. On AP abdominal film a T-shaped intrauterine device (IUD) with calculus was noted in the pelvis. By ...

  2. Large functional benign endometroid cystadenofibroma of the ovary leading to endometrial cystic glandular hyperplasia and postmenopausal bleeding

    OpenAIRE

    Singh, Nilanchali; Tripathi, Reva; Mala, Yedla Manikya; Khurana, Neeta; Khan, Mumtaz

    2013-01-01

    Benign endometroid cystadenofibroma of the ovary is a rare tumour with few reported cases. The association of endometroid cystadenofibroma with endometrial cystic glandular hyperplasia has not been previously reported to authors’ knowledge. We are reporting a 75-year-old postmenopausal woman who presented with a large abdominopelvic mass corresponding to 30?weeks size gravid uterus and postmenopausal bleeding. She has a well-oestrogenised vagina. Ultrasound pelvis revealed a large cystic mass...

  3. Trichomonas vaginalis adherence mediates differential gene expression in human vaginal epithelial cells

    OpenAIRE

    Kucknoor, Ashwini; Mundodi, Vasanthakrishna; Alderete, John F.

    2005-01-01

    Trichomonas vaginalis, an ancient protist, colonizes the vaginal mucosa causing trichomonosis, a vaginitis that sometimes leads to severe health complications. Preparatory to colonization of the vagina is the adhesion to vaginal epithelial cells (VECs) by trichomonads. We hypothesized that VECs alter the gene expression to form a complex signalling cascade in response to trichomonal adherence. In order to identify the genes that are upregulated, we constructed a subtraction cDNA library after...

  4. Dystopic dysplastic kidney with ectopic ureter: improved localization by fusion of MR urography and {sup 99m}Tc-DMSA SPECT datasets

    Energy Technology Data Exchange (ETDEWEB)

    Kreissl, Michael C.; Lorenz, Reinhard [University Clinic Wuerzburg, Clinic and Polyclinic of Nuclear Medicine, Wuerzburg (Germany); Ohnheiser, Gerd [University Clinic Wuerzburg, Zentrum Operative Medizin, Clinic and Polyclinic of Urology, Wuerzburg (Germany); Darge, Kassa [University Clinic Wuerzburg, Department of Paediatric Radiology, Institute of Radiodiagnosis, Wuerzburg (Germany)

    2008-02-15

    We report a 12-year-old girl with a long history of constant urinary dribbling and apparently only a left kidney. Using a multimodality approach involving the fusion of MR urography and {sup 99m}Tc-dimercaptosuccinic acid (DMSA) SPECT datasets, it was finally possible to exactly localize the very small dystopic, dysplastic right kidney and its ectopic ureter draining into the vagina. (orig.)

  5. Dynamics of Streptococcus agalactiae colonization in women during and after pregnancy and in their infants

    DEFF Research Database (Denmark)

    Hansen, Søren Mose; Uldbjerg, Niels; Kilian, Mogens; Sørensen, Uffe B Skov

    2004-01-01

    The population dynamics of Streptococcus agalactiae (group B streptococci [GBS]) colonization of the vagina and anorectal area was investigated in a cohort of 77 Danish women during and after their pregnancy by a new sensitive method. The mean carriage rate among individual observations was 36%, and the cumulative carriage rate over the entire observation period was 54%. Examination of more than 1500 GBS isolates by pulsed-field gel electrophoresis demonstrated that the GBS population was remark...

  6. Malformations in a cohort of 284 women with Mayer-Rokitansky-Küster-Hauser syndrome (MRKH

    Directory of Open Access Journals (Sweden)

    Oppelt Patricia G

    2012-08-01

    Full Text Available Abstract Background The aim of this retrospective study was to describe the spectrum of genital and associated malformations in women with Mayer-Rokitansky-Küster-Hauser syndrome using evaluated diagnostic procedures and the Vagina Cervix Uterus Adnex – associated Malformation classification system (VCUAM. Methods 290 women with MRKH syndrome were clinically evaluated with using clinical examinations, abdominal and perineal/rectal ultrasound, MRI, and laparoscopy. Results Classification of female genital malformation according to the Vagina Cervix Uterus Adnex – associated Malformation classification system was possible in 284 women (97.9%. Complete atresia of Vagina (V5b and bilateral atresia of Cervix (C2b were found in 284 patients (100%. Uterus: bilateral rudimentary or a plastic uterine horns were found in 239 women (84.2%. Adnexa: normal Adnexa were found in 248 women (87.3%. Malformations: associated malformations were found in 126 of 282 evaluable women (44.7%, 84 women (29.6% had malformations of the renal system. Of 284 women with Mayer-Rokitansky-Küster-Hauser syndrome 212 women (74.7% could be classified as V5bC2bU4bA0. The most frequent classification was V5bC2bU4bA0M0 (46.8% diagnosed in 133 of 284 women. Conclusions Complete atresia of vagina and cervix were found in all patients, variable malformations were found with uterus and adnexa. A variety of associated malformations were present, predominantly of the renal system. It is therefore recommended that all patients with genital malformations should be evaluated for renal abnormalities.

  7. Female form of persistent mullerian duct syndrome: Rare entity.

    Science.gov (United States)

    Solanki, Shailesh; Gowrishankar; Jadhav, Vinay; Babu, M Narendra; Ramesh, S

    2015-01-01

    Persistent Mullerian duct syndrome (PMDS) is a rare form of Disorder of sex development in which Mullerian duct derivatives (fallopian tubes, uterus and the proximal vagina) are present in an otherwise normally differentiated 46 XY male. In the majority of cases, PMDS is a surprise finding either during orchidopexy or during inguinal hernia repair. We report a case of 4 year child with female type (Type III) PMDS. We are discussing the presentation, management and review of the literature. PMID:25657558

  8. Cuando los cuerpos engañan: un acercamiento crítico a la categoría de la intersexualidad

    OpenAIRE

    Aracelis Escab\\u00ED-Montalvo; Jos\\u00E9 Toro-Alfonso

    2006-01-01

    Tradicionalmente se considera a los genitales como la marca que determinará el género de las personas. Sin embargo, en el caso de la intersexualidad se rompe con las dicotomías del sexo/género, específicamente con la de hombre = pene y vagina = mujer. El término intersexualidad se utiliza para representar aquellos cuerpos que poseen genitales que no corresponde a la representación típica fisiológica de los genitales de una mujer ni la de un hombre. Tradicionalmente, desde la Me...

  9. Vaginal reconstruction with the Abbe-McIndoe technique in Mayer Rokitansky Kuster Hauser syndrome: a case report

    OpenAIRE

    Sujata Swain; Abarajda Dilip; Prithviraj Singh; Rabi Narayan Satpathy

    2015-01-01

    The Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome is a rare but well discussed entity characterized by congenital aplasia of the uterus and the upper part (2/3rd) of the vagina in women with normal development of secondary sexual characteristics and a normal 46, XX karyotype. The inability to lead a normal sexual and reproductive life bears a great amount of social inhibition and psychological distress on the affected individuals. The physical inability can definitely be attended to by vari...

  10. Vaginal Versus Sublingual Misoprostol for Labor Induction at Term and Post Term: a Randomized Prospective Study

    OpenAIRE

    Ayati, Sedigheh; Vahidroodsari, Fatemeh; Farshidi, Farnoosh; Shahabian, Masoud; Afzal Aghaee, Monavar

    2014-01-01

    We want to compare the efficacy and safety of vaginal versus sublingual misoprostol for cervical ripening and induction of labor. This randomized clinical trial was performed on 140 women with medical or obstetric indications for labor induction. The patients were randomly divided into two groups: vaginal and sublingual administration of misoprostol. In first group, 25 µg misoprostol was placed in the posterior fornix of the vagina and second group received 25 µg misoprostol sublingually, eve...

  11. Chronic candidiasis - pathogenesis, symptoms, diagnosis and treatment

    OpenAIRE

    Klajn-Laslo Marija

    2009-01-01

    The yeast named Candida normally colonizes the gut and vagina without causing any sign of its presence. It is a commensal and opportune fungus but in certain conditions it turns to be pathogenic, causing chronic disturbances in any part of the body. The pathogenesis is complex, signs and symptoms are non-specific. The colonisation is difficult to distinguish from invasive disease. The current diagnostic methods do not always allow a definitive diagnosis to be made. Treatment is complex, indiv...

  12. AN UNCONSUMMATED MARRIAGE: A CASE REPORT

    OpenAIRE

    Ersin Akp?nar; Esra Saatç?

    2007-01-01

    Vaginismus is described as “recurrent or persistent involuntary contraction of the perineal muscles surrounding the outer third of the vagina when vaginal penetration is attempted with penis, finger, tampon, or speculum. The purpose of this case report is to investigate the treatment model of a patient with vaginismus who benefited from Cognitive Behavioral Therapy (CBT) in a couple (woman 21, man 23 years old) admitting to family practice for treatment of vaginismus. The duration of marriage...

  13. Insects are Crawling in My Genital Warts

    OpenAIRE

    Jyoti Dhawan; Saurabh Singh,; Somesh Gupta

    2011-01-01

    A 23-year-old woman presented with large exophytic genital wart arising from perineum, vulva, introitus of the vagina, and inner aspect of thighs. Patient developed severe itching and formication (insect-crawling sensation) in the lesions for past 1 week, though careful examination did not reveal any insects. Considering that the disease was causing psychological stress and physical symptoms, radiofrequency excision was planned. However, during the procedure, several maggots appeared from the...

  14. Adjunctive Pessary Therapy after Emergency Cervical Cerclage for Cervical Insufficiency with Protruding Fetal Membranes in the Second Trimester of Pregnancy: A Novel Modification of Treatment

    OpenAIRE

    Katarzyna Kosinska-Kaczynska; Dorota Bomba-Opon; Aleksandra Zygula; Bartosz Kaczynski; Piotr Wegrzyn; Miroslaw Wielgos

    2015-01-01

    Aim. To evaluate the effectiveness of adjunctive pessary therapy after emergency cervical cerclage (ECC) in improving perinatal outcome in cervical insufficiency with fetal membranes protruding into the vagina. Material and Methods. A retrospective analysis of patients treated at the 1st Department of Obstetrics and Gynecology, Medical University of Warsaw, between 2008 and 2013. The study group consisted of 15 women treated with ECC and a pessary and the control group consisted of 17 patient...

  15. Rectal extrusion of the catheter and air ventriculography following bowel perforation in ventriculo-peritoneal shunt

    Energy Technology Data Exchange (ETDEWEB)

    Arico, M.; Podesta, A.F.; Bianchi, E.; Beluffi, G.; Fiori, P.; Chiari, G.; Pezzotta, S.

    1985-01-01

    Ventriculo-peritoneal shunt is frequently carried out in infantile hydrocephalus. The peritoneal shunt has a lower morbidity than ventriculo-atrial shunt and severe complications are uncommon. Abdominal complications include intestinal perforation, shunt migration, inguinal hernia, cerebrospinal fluid pseudocysts and hollow viscus perforation. A few cases of catheter extrusion from the rectum, vagina, umbilicus and urethra have been described. We report a new case of intestinal perforation with rectal extrusion of the catheter associated with a ventriculogram.

  16. Description of Paktylenchus tuberosus gen. n., sp. n. (Nematoda: Tylenchinae)

    OpenAIRE

    M. A. Maqbool

    1983-01-01

    Paktylenchus tuberosus gen.n., sp.n. is described and illustrated from soil around Solanum tuberosum from Kaghan Valley, Pakistan. Paktylenchus gen.n, can be distinguished from the most closely related genus, Agelenchus Andrassy, 1954, by the distinct longitudinal striae, three incisures in the lateral field, and absence of males. Paktylenchus tuberosus shows affinities to Coslenchus Siddiqi, 1978 but differs in having an oblique vagina-to-body axis and a prominent sunken vulva with vulval fl...

  17. Palmar dermatoglyphics as diagnostic tool: Mayer-rokintansky-kuster-hauser syndrome

    OpenAIRE

    Kumar A; Manou S

    2003-01-01

    The congential anomalies involving Mullerian duct dysgenesis, the MRKH (Mayer-Rokitansky-Kuster-Hauser) syndrome overlaps a ?community of syndromes? which share, apart from a complete absence of uterus and vagina, associated presentations that include developmental abnormalities of skeletal, renal, dental and other dysmorphias. First described more than 400 years ago, this complement of anomalies now rechristened, the MRKH syndrome has been extensively studied. Found to occur on...

  18. Anterior vaginal wall repair using local anaesthesia

    DEFF Research Database (Denmark)

    Bek, Karl Møller; Axelsen, Susanne Maigaard

    2004-01-01

    BACKGROUND: The purpose of the present study was to describe the possibility of surgical repair of anterior vaginal prolapse including amputation of the cervix using local anaesthesia. The description was made according to postoperative complication, recurrence rate, influence on urinary incontinence, and satisfaction of the patient. MATERIAL AND METHODS: Eighty-three women were consecutively operated in the anterior wall of the vagina using local anaesthesia and intravenously supplemented with ...

  19. CONGENITAL VESICOUTERINE FISTULA ALONG WITH DISTAL VAGINAL AGENESIS, SOLITARY KIDNEY AND TONGUE TIE: A RARITY

    OpenAIRE

    Khalid; #, Amit; Rana Pratap; Ahsan; Takallum

    2015-01-01

    : Congenital vesicouterine fistula in association with vaginal agenesis and solitary renal agenesis has been rarely reported. We present a case of 19 year old female suffering from cyclical menouria for last years. Physical examination revealed absence of vagina. IVP revealed left renal agenesis and CT scan revealed left renal agenesis with vesicouterine fistula. Cystoscopy showed vesicouterine fistula located above trigone near midline. Vesicouterine fistula was repaired along wi...

  20. A 20-Year-Old Contraceptive Device Transformed into a Calcified Mass

    OpenAIRE

    Awatuf Elshirif; Seema Sadiq

    2014-01-01

    Case: A 52-year-old female who was presented to accident and emergency felt unwell; she reported that she had an IUCD inserted over 20 years ago. On examination she had a large calcified mass occupying the vagina. CT scan confirmed a calcified IUCD. Conclusion: Serious complication secondary to IUCD is rare but well recorded, extensive calcification as in this case is very rare and has not been previously reported.

  1. Investigation of vaginal microbiota in sexually active women using hormonal contraceptives in Pakistan

    OpenAIRE

    Kazi Yasmeen; Saleem Sobia; Kazi Nasreen

    2012-01-01

    Abstract Background Previous studies report association of contraceptives with moderate increase in urinary tract infection among sexually active premenopausal women. The aim of our study was to find out whether the use of hormonal contraceptives has any effect on microbiota of the vagina in the contraceptives users in Khairpur Sindh Pakistan. Methods A prospective study in woman population of Khairpur Sindh Pakistan aged 20–30 years and 31–40 years, using Hormonal contraceptives was carried ...

  2. Bacterial vaginosis biofilms: challenges to current therapies and emerging solutions

    OpenAIRE

    Machado, D.; J. Castro; Oliveira, Ana Palmeira de; Oliveira, José Martinez de; Cerca, Nuno

    2016-01-01

    Bacterial vaginosis (BV) is the most common genital tract infection in women during their reproductive years and it has been associated with serious health complications, such as preterm delivery and acquisition or transmission of several sexually transmitted agents. BV is characterized by a reduction of beneficial lactobacilli and a significant increase in number of anaerobic bacteria, including Gardnerella vaginalis, Atopobium vaginae, Mobiluncus spp., Bacteroides spp. and Prevotella spp.. ...

  3. [Study of vaginal and intestinal microflora of women in the prenatal period and its correction in dysbacteriosis].

    Science.gov (United States)

    Podgorski?, V S; Liaskovski?, T M; Kovalenko, N K; Oleshchenko, L T

    2006-01-01

    A comparative research of the structure of vaginal and intestinal microflora in norm and at kidney pathologies in women in the prenatal period was carried out. At physiologically normal course of pregnancy microbiocenosis of vagina and intestine does not contain pathogenic and conditional-pathogenic microorganisms. Lactic acid bacteria are fixed within the limits of 10(5)-10(8) CFU/1 ml in the vagina secretion and 10(7)-10(8) CFU/1 g in the intestine content. The spore microorganisms have completely disappeared in vaginal biocenosis of women with pyelonephritis after pharmacotherapy; and colibacterias has disappeared in 62% of women. Quantity of lactic acid bacteria has also decreased. Quantity of E. coli (10(8)- 10(9)) CFU/g, sporous microorganisms (10(3)-10(4)) CFU/g and yeast (10(4)-10(5)) CFU/g has considerably increased in the content of intestine. Lactic acid bacteria in content of the vagina are presented by: Lactobacillus acidophilus, L. plantarum, L. fermentum, L. vaginalis; in content of the intestine--L. plantarum and L. fermentum. All the isolated strains of lactobacilli are resistant to metrogyl and amphotericin, 87%--to cephoxitine, cypropfloxacine. Twenty three of 24 strains of lactic acid bacteria--antagonists of pathogenic microflora have shown adhesion to vaginal epthelium. The degree of adhesive activity depends on the strain and genus specificity of cultures. The highest index of adhesiveness in indicated in Enterococcus faecium (5.82 - 7.62) and Streptococcus salivarius subsp. thermophilus (2.74 - 6.40) strains. The screening of strains has been performed, which suppress growth of gas-producing microflora. The strain of Lactobacillus plantarum 200D proved to be the most active one. A complex of cultures of the lactic bacteria providing normalization of microbial cenosis of the vagina in women in the prenatal period has been selected as based on the data obtained. The biotechnology of production of vaginal suppositories is developed. PMID:16786633

  4. Vaginal Vault Prolapse

    OpenAIRE

    K. A. Farag; Azubuike Uzoma

    2009-01-01

    Introduction. Vaginal vault prolapse is a common complication following vaginal hysterectomy with negative impact on women's quality of life due to associated urinary, anorectal and sexual dysfunction. A clear understanding of the supporting mechanism for the uterus and vagina is important in making the right choice of corrective procedure. Management should be individualised, taking into consideration the surgeon's experience, patients age, comorbidities, previous surgery and sex life. Resul...

  5. EFFECT OF CERTAIN YOGIC ASANAS ON THE PELVIC CONGESTION AND IT'S ANATOMY

    OpenAIRE

    Mishra, Satyendra Prasad; Singh, R. H.

    1984-01-01

    20 patient including 6 females and 14 males, between 20 years to 30 years of age, with complaints of chronic constipation refractory to various treatments by medicines, belching, sense of heaviness in the lower abdomen or pelvic region, offensive discharge from vagina (leucorrhoea) and bleeding per rectum with discomfort in the region of perineum were observed under instructions and supervision to practice certain yogic exercises for a period of three years. Viparitakarani, Goraksa asana, Udd...

  6. The consequences of yield stress on deployment of a non-Newtonian anti-HIV microbicide gel

    OpenAIRE

    Tasoglu, Savas; Park, Su Chan; Peters, Jennifer J.; Katz, David F.; Szeri, Andrew J

    2011-01-01

    A recent study in South Africa has confirmed, for the first time, that a vaginal gel formulation of the antiretroviral drug Tenofovir, when applied topically, significantly inhibits sexual HIV transmission to women [10]. However the gel for this drug, and anti-HIV microbicide gels in general, have not been designed using full understanding of how gel spreading and retention in the vagina govern successful drug delivery. Elastohydrodynamic lubrication theory can be applied to model such spread...

  7. The effects of inhomogeneous boundary dilution on the coating flow of an anti-HIV microbicide vehicle

    OpenAIRE

    Tasoglu, Savas; Peters, Jennifer J.; Park, Su Chan; Verguet, Stéphane; Katz, David F.; Szeri, Andrew J

    2011-01-01

    A recent study in South Africa has confirmed, for the first time, that a vaginal gel formulation of the antiretroviral drug Tenofovir, when topically applied, significantly inhibits sexual HIV transmission to women [Karim et al., Science 329, 1168 (2010)]. However, the gel for this drug and anti-HIV microbicide gels in general have not been designed using an understanding of how gel spreading and retention in the vagina govern successful drug delivery. Elastohydrodynamic lubrication theory ca...

  8. Pharmacomicrobiomics : the impact of human microbiome variations on systems pharmacology and personalized therapeutics

    OpenAIRE

    ElRakaiby, Marwa; Dutilh, Bas E.; Rizkallah, Mariam R; Boleij, Annemarie; Cole, Jason N; Aziz, Ramy K

    2014-01-01

    The Human Microbiome Project (HMP) is a global initiative undertaken to identify and characterize the collection of human-associated microorganisms at multiple anatomic sites (skin, mouth, nose, colon, vagina), and to determine how intra-individual and inter-individual alterations in the microbiome influence human health, immunity, and different disease states. In this review article, we summarize the key findings and applications of the HMP that may impact pharmacology and personalized thera...

  9. Vaginoplasty for disorders of sex development

    Directory of Open Access Journals (Sweden)

    GiacintoA.Marrocco

    2013-03-01

    Treatment options: Treatment of these patients is under discussion and may consist, basically, in non-operative dilation methods or surgical creation of a neo-vagina. Consensus is far to be reached among the various surgical subspecialties regarding the optimal method of vaginal replacement. Adequate number of long term follow up patients are still non available so that most conclusions are based on small number series. The authors describe the different treatment options in detail.

  10. Macroscopic Morphometric Analysis of Genital Organs of Rabbit does with Differing Parturitions at 24 Hours Post-weaning / Análisis Morfométrico Macroscópico de Órganos Genitales de Conejas con Diferentes Partos a las 24 Horas Post-destete

    Scientific Electronic Library Online (English)

    Jesús, Aragón-Hernández; Fernando Iván, Flores-Pérez; Claudia, Hallal-Calleros; Mario, Pérez-Martínez.

    2013-09-01

    Full Text Available El propósito de este estudio fue analizar la morfometría macroscópica de los ovarios, útero y vagina en conejas de primero, segundo y tercer parto a las 24 horas post-destete con el propósito de determinar si existen diferencias entre los partos. El destete de la camada se realizó a los 30 días desp [...] ués del parto y 24 horas después fueron eutanasiadas. De cada animal se removieron los ovarios derecho e izquierdo, cuernos-cuello uterinos derecho e izquierdo y la vagina y se midió la longitud de cada uno de los órganos genitales. Se encontraron diferencias significativas en la longitud del ovario derecho entre el grupo de primer parto con respecto al de segundo y tercer parto (P 0,05 y P 0,01). Además, la longitud media de ovario izquierdo fue significativamente diferente entre el grupo de primero y segundo parto con respecto al de tercer parto (P Abstract in english The purpose of this study was to analyze the macroscopic morphometry of the ovaries, uterus and vagina in rabbit does in the first, second and third parturition at 24 hours post-weaning in order to determine if there are differences between parturitions. Weaning of the litter was performed at 30 day [...] s post-partum and 24 hours later the does were euthanized. Right and left ovaries, uterine horns-cervix and vagina were removed, and the length of each one was measured. Significant differences were found in the average of the right ovary length between the first group with respect to second and third parturition group (P 0.05 and P 0.01). Also, left ovary length was different between the first and second with respect to third parturition group (P

  11. Influence of addition of different antibiotics in semen diluent on viable bacterial count and spermatozoal viability of Awassi ram semen

    OpenAIRE

    O. I. Azawi; M A Ismaeel

    2012-01-01

    The objectives of the present study were to determine the effects of six different antibiotics in controlling the growth of semen contaminating bacteria and if these antibiotics have any adverse effect on Awassi ram spermatozoa. Semen samples from six mature Awassi rams were used in this study. A total number of 120 ejaculates were collected from the rams using an artificial vagina once a week. Semen ejaculates were evaluated for volume, sperm concentration, mass motility, individual motility...

  12. REPAIR OF POSTERIOR VAGINAL WALL DEFECTS WITH PELVICOL™ IMPLANT ANCHORED TO ILIOCOCCYGEUS

    OpenAIRE

    R. Ripoli; P. Liguori

    2010-01-01

    Pelvic floor prolapse is a frequent condition in the female population, inevitably deemed to increase with the population average age increase. If quality of life of women suffering from pelvic prolapse is investigated, the impact of symptoms may result dramatic, causing psychological, relational, sexual, working problems. Posterior vaginal wall defects are classified as rectocele and enterocele. Rectocele means hernia or protrusion of the anterior wall of rectum in vagina, such condition bei...

  13. Adaptive Plasticity of Vaginal Innervation in Term Pregnant Rats

    OpenAIRE

    Liao, Zhaohui; Peter G. SMITH

    2011-01-01

    Changes in reproductive status place varied functional demands on the vagina. These include receptivity to male intromission and sperm transport in estrus, barrier functions during early pregnancy, and providing a conduit for fetal passage at parturition. Peripheral innervation regulates vaginal function, which in turn may be influenced by circulating reproductive hormones. We assessed vaginal innervation in diestrus and estrus (before and after the estrous cycle surge in estrogen), and in th...

  14. Congenital Pouch Colon associated with Pseudoexstrophy: Report of Two Cases.

    Science.gov (United States)

    Jhanwar, Praveen; Shinde, Nand Kishor; Patel, Jigar N; Pant, Nitin; Chadha, Rajiv

    2016-01-01

    This report describes two newborn girls with single perineal opening (cloaca), and pseudoexstrophy in the form of divergent pubic bones and rectus muscles, and a low-set umbilicus. Both patients had a type II congenital pouch colon (CPC) with one hemiuterus and vagina on each side in the pelvis. In one patient, a Meckel's diverticulum was present 5 cm from the ileocecal junction. In both girls, a diverting proximal ileostomy was the initial surgery. PMID:26814054

  15. Congenital Pouch Colon associated with Pseudoexstrophy: Report of Two Cases

    Directory of Open Access Journals (Sweden)

    Praveen Jhanwar

    2016-01-01

    Full Text Available This report describes two newborn girls with single perineal opening (cloaca, and pseudoexstrophy in the form of divergent pubic bones and rectus muscles, and a low-set umbilicus. Both patients had a type II congenital pouch colon (CPC with one hemiuterus and vagina on each side in the pelvis. In one patient, a Meckel’s diverticulum was present 5 cm from the ileocecal junction. In both girls, a diverting proximal ileostomy was the initial surgery.

  16. Prevalence of Gardnerella vaginalis in the Urinary Tract

    OpenAIRE

    1989-01-01

    Midstream urine samples from 106 patients presenting to the Casualty Department of The Royal Melbourne Hospital with frequency or dysuria were cultured for Gardnerella vaginalis and conventional uropathogens. Urine samples collected via an open-end catheter from 70 healthy pregnant women were examined similarly. Midstream urine and other samples, including the seminal fluids and swabs of the mouths, throats, rectums, and vaginas of 33 healthy subjects, were cultured for G. vaginalis. Another ...

  17. Multiplex Detection of Bacteria Associated with Normal Microbiota and with Bacterial Vaginosis in Vaginal Swabs by Use of Oligonucleotide-Coupled Fluorescent Microspheres? †

    OpenAIRE

    Dumonceaux, Tim J.; Schellenberg, John; Goleski, Vanessa; Hill, Janet E.; Jaoko, Walter; Kimani, Joshua; Money, Deborah; Ball, T Blake; Plummer, Francis A.; Severini, Alberto

    2009-01-01

    Bacterial vaginosis (BV) is a recurrent condition that is associated with a range of negative outcomes, including the acquisition of human immunodeficiency virus and other sexually transmitted diseases, preterm births, and pelvic inflammatory disease. In contrast to the Lactobacillus-dominated normal vaginal microbiota, BV is characterized by a lack of lactobacilli and an abundance of anaerobic and gram-negative organisms, including Gardnerella vaginalis and Atopobium vaginae. To date, the la...

  18. Oral Low-Molecular Weight Hyaluronic Acid in the Treatment of Atrophic Vaginitis

    OpenAIRE

    Tindara La Galia; Antonio Micali; Domenico Puzzolo; Francesco Cancellieri

    2014-01-01

    The aim of this study was to evaluate the effectiveness of low molecular weight hyaluronic acid oral tablets for the treatment of atrophic vaginitis. 12 women with atrophic vaginitis were recruited for this double blind, placebo-controlled study. Patients were randomized to receive either low molecular weight hyaluronic acid (HA) oral tablets or placebo for three months. Vaginal biopsies were taken at baseline and after three months of treatment, and vagina...

  19. Vaginal Atrophy following Long-Term Depot Medroxyprogesterone Acetate Use: A Case Report

    OpenAIRE

    Christie Walker; Badawy, Shawky Z. A.

    2013-01-01

    Depot medroxyprogesterone acetate (DMPA) is a commonly used form of contraception, with noncontraceptive benefits for the user. The mode of action is through the suppression of ovulation. It leads to hypoestrogenism which causes dryness of the vagina and dyspareunia. We present in this paper a patient that was very symptomatic with regard to vaginal atrophic changes determined by vaginal cytology. This side effect may become increasingly more common as we see more long-term use of DMPA.

  20. Obstetric and gynaecological profile in patients with primary Sjögren's syndrome.

    OpenAIRE

    Skopouli, F N; S. Papanikolaou; Malamou-Mitsi, V.; Papanikolaou, N.; Moutsopoulos, H. M.

    1994-01-01

    OBJECTIVE--To describe the effects of Sjögren's syndrome (SS) on the fertility, parity and sexual activity as well as investigating the aetiopathology of dyspareunia in female patients. METHODS--Fifty one female patients with primary SS (pSS) and 57 healthy controls were interviewed concerning their past gynaecological, obstetric and sexual history and underwent a complete gynaecological examination. Punch biopsy of the vagina was performed in six patients and one healthy individual. In addit...

  1. Malignant neoplasms of decidual origin (deciduosarcomas) induced by estrogen-progestin-releasing intravaginal devices in rabbits.

    OpenAIRE

    Zook, B. C.; Spiro, I.; Hertz, R

    1987-01-01

    A combination of estrogen and levonorgestrel was continuously delivered to 23 adult rabbits for up to 2 years via a Silastic ring device sutured into the vagina. Twenty-one control rabbits were given similar rings devoid of drugs. A marked decidual reaction of the endometrium occurred in 16 of 23 test rabbits. In 14 test rabbits (61%) malignant tumors developed of decidual type cells not heretofore described. The deciduosarcomas were composed of anaplastic cells that invaded the uterine walls...

  2. Mioma vaginal: reporte de un caso

    Directory of Open Access Journals (Sweden)

    Carmen Mantellini

    2011-03-01

    Full Text Available Objetivo: Presentar un caso de mioma vaginal en una mujer de 52 años. Caso. Paciente asintomática, que acude a la consulta para control ginecológico. Se detecta una lesión en cara posterior de vaginal, sobre elevada e hiperpigmentada de aproximadamente 1 cm de diámetro, la cual fue extirpada con asa diatérmica; se envió el material para estudio histopatológico y el resultado fue leiomioma en vagina con hiperpigmentación melánica en la capa basal del epitelio. La paciente evolucionó bien.

  3. Clinic diagnosis of anaerobic vaginosis (non-specific vaginitis). A practical guide.

    OpenAIRE

    Blackwell, A; Barlow, D.

    1982-01-01

    Anaerobic vaginosis (non-specific vaginitis) can be readily diagnosed at the time of first attendance without recourse to expensive and time-consuming laboratory investigations. Diagnosis is based on careful history-taking, clinical examination, and simple investigations in the clinic. Although the presence of a malodorous vaginal discharge and the finding of clue cells on microscopy (in the absence of Trichomonas vaginalis) are sufficient for the diagnosis, a positive amine test and a vagina...

  4. Spermicidal activity of the crude ethanol extract of Sedum praealtum in mice.

    Science.gov (United States)

    Silva-Torres, Rafael; Montellano-Rosales, Hortensia; Ramos-Zamora, Delfina; Castro-Mussot, M Eugenia; Cerda-García-Rojas, Carlos M

    2003-03-01

    Ethanol extract of Sedum praealtum in intravaginal doses of 10, 20, 40, 50, 100 and 150 mg/kg body weight showed a toxic effect in spermatozoa viability after 24h of administration. Spermatozoa viability was 94, 83, 58 and 24%, respectively, for extract doses of 10, 20, 40 and 50mg/kg body weight, while only dead spermatozoa were found in the vagina of the treated female mice with doses of 100 and 150 mg/kg body weight. PMID:12576197

  5. HPV-Related Cancers after Solid Organ Transplantation in the US

    OpenAIRE

    Madeleine, M.M.; Finch, J L; Lynch, C F; Goodman, M.T.; Engels, E A

    2013-01-01

    Transplant recipients have elevated cancer risk including risk of human papillomavirus (HPV)-associated cancers of the cervix, anus, penis, vagina, vulva, and oropharynx. We examined the incidence of HPV-related cancers in 187,649 U.S. recipients in the Transplant Cancer Match Study. Standardized incidence ratios (SIRs) compared incidence rates to the general population, and incidence rate ratios (IRR) compared rates across transplant subgroups. We observed elevated incidence of HPV-related c...

  6. Selected Background Findings and Interpretation of Common Lesions in the Female Reproductive System in Macaques

    OpenAIRE

    Cline, J Mark; Wood, Charles E; Vidal, Justin D.; Tarara, Ross P; Buse, Eberhard; Weinbauer, Gerhard F.; de Rijk, Eveline P. C. T.; Esch, Eric

    2008-01-01

    The authors describe a selection of normal findings and common naturally occurring lesions in the reproductive system of female macaques, including changes in the ovaries, uterus, cervix, vagina, and mammary glands. Normal features of immature ovaries, uteri, and mammary glands are described. Common non-neoplastic lesions in the ovaries include cortical mineralization, polyovular follicles, cysts, ovarian surface epithelial hyperplasia, and ectopic ovarian tissue. Ovarian neoplasms include gr...

  7. A New Era of the Vaginal Microbiome: Advances using Next-Generation Sequencing

    OpenAIRE

    Fettweis, Jennifer M; Serrano, Myrna G.; Girerd, Philippe H.; Jefferson, Kimberly K; Buck, Gregory A.

    2012-01-01

    Until recently, bacterial species that inhabit the human vagina have been primarily studied using organism-centric approaches. Understanding how these bacterial species interact with each other and the host vaginal epithelium is essential for a more complete understanding of vaginal health. Molecular approaches have already led to the identification of uncultivated bacterial taxa associated with bacterial vaginosis. Here, we review recent studies of the vaginal microbiome and discuss how cult...

  8. Species-level classification of the vaginal microbiome

    OpenAIRE

    Fettweis Jennifer M; Serrano Myrna G; Sheth Nihar U; Mayer Carly M; Glascock Abigail L; Brooks J Paul; Jefferson Kimberly K; Buck Gregory A

    2012-01-01

    Abstract Background The application of next-generation sequencing to the study of the vaginal microbiome is revealing the spectrum of microbial communities that inhabit the human vagina. High-resolution identification of bacterial taxa, minimally to the species level, is necessary to fully understand the association of the vaginal microbiome with bacterial vaginosis, sexually transmitted infections, pregnancy complications, menopause, and other physiological and infectious conditions. However...

  9. Anatomy and histology of apical support: a literature review concerning cardinal and uterosacral ligaments

    OpenAIRE

    Ramanah, Rajeev; Berger, Mitchell B.; Parratte, Bernard M.; Delancey, John O.L.

    2012-01-01

    The objective of this work was to collect and summarize relevant literature on the anatomy, histology, and imaging of apical support of the upper vagina and the uterus provided by the cardinal (CL) and uterosacral (USL) ligaments. A literature search in English, French, and German languages was carried out with the keywords apical support, cardinal ligament, transverse cervical ligament, Mackenrodt ligament, parametrium, paracervix, retinaculum uteri, web, uterosacral ligament, and sacrouteri...

  10. An Overview of Neovaginal Reconstruction Options in Male to Female Transsexuals

    OpenAIRE

    Marta Bizic; Vladimir Kojovic; Dragana Duisin; Dusan Stanojevic; Svetlana Vujovic; Aleksandar Milosevic; Gradimir Korac; Djordjevic, Miroslav L.

    2014-01-01

    Transsexualism is a complex condition in which the person experiences the inconsistency between the desired gender and their biological gender. Absence of the vagina is devastating in male to female transsexuals. Creation of the neovagina is the main surgical problem in these patients. Historically, beginnings of the neovaginal creation have their roots in the treatment of Mayer-Rokitansky syndrome and conditions such as cloacal anomalies, certain intersex disorders, vaginal malignancies, or ...

  11. Cell-mediated Immunity to HIV in the Female Reproductive Tract

    OpenAIRE

    SHACKLETT, Barbara L.

    2009-01-01

    The majority of HIV infections occur via sexual transmission across a mucosal barrier. In the case of male-to-female transmission, HIV-susceptible target cells are abundant in the ectocervix and vagina but are also present in the upper reproductive tract (endocervix and uterus). While the mechanisms of HIV transmission in the female reproductive tract are an active area of investigation, cell-mediated immune responses in reproductive tissues have not been thoroughly characterized. HIV-specifi...

  12. Placenta accrete treated with uterine arterial embolization (case report)

    International Nuclear Information System (INIS)

    Objective: To investigate the possibility of interventional treatment of placenta accrete. Methods: One patient with placenta accrete was treated with uterine arterial infusion of cef and MTX followed by embolization. Results: Her placenta discharged through vagina at the 27 th day after uterine arterial embolization. No remnant was found in the uterine by Doppler imaging. The patient uneventfully recovered. Conclusions: Interventional therapy with uterine arterial embolization is a new and reliable method for treatment for placenta accrete

  13. Two Neonates with Congenital Hydrocolpos

    OpenAIRE

    Kristin Voos; Julie Weiner; Vydehi Murthy; Jessica Costalez

    2013-01-01

    Introduction. Neonatal hydrocolpos is a rare condition. Hydrocolpos is cystic dilatation of the vagina with fluid accumulation due to a combination of stimulation of secretary glands of the reproductive tract and vaginal obstruction. The differential for a neonatal presentation of lower abdominal mass includes urogenital anomalies, Hirschsprung's, disease or sacrococcygeal teratoma. Prenatal diagnosis and early newborn imaging studies leads to early detection and treatment of these cases. Cas...

  14. Complex Genital Malformation in a Female with Congenital Adrenal Hyperplasia: Evaluation with Magnetic Resonance Imaging

    Energy Technology Data Exchange (ETDEWEB)

    Klessen, C.; Asbach, P.; Hein, P. A.; Beyersdorff, D.; Hamm, B.; Taupitz, M. [Humboldt-Univ. of Berlin, Campus Charite Mitte (Germany). Dept. of Radiology

    2005-12-01

    This is a case of complex genital malformation in a young patient with congenital adrenal hyperplasia. The magnetic resonance imaging (MRI) findings included ostium of the vagina into the urethra (common urogenital opening), prostate-like tissue surrounding the urethra, and hyperplasia of the left adrenal gland. The report provides information on the clinical findings, the MRI examination, including the applied sequences and the MR findings, and gives an overview of the disease pattern and its frequency of occurrence.

  15. Malformations in a cohort of 284 women with Mayer-Rokitansky-Küster-Hauser syndrome (MRKH)

    OpenAIRE

    Oppelt Patricia G; Lermann Johannes; Strick Reiner; Dittrich Ralf; Strissel Pamela; Rettig Ingo; Schulze Christine; Renner Stefan P; Beckmann Matthias W; Brucker Sara; Rall Katharina; Mueller Andreas

    2012-01-01

    Abstract Background The aim of this retrospective study was to describe the spectrum of genital and associated malformations in women with Mayer-Rokitansky-Küster-Hauser syndrome using evaluated diagnostic procedures and the Vagina Cervix Uterus Adnex – associated Malformation classification system (VCUAM). Methods 290 women with MRKH syndrome were clinically evaluated with using clinical examinations, abdominal and perineal/rectal ultrasound, MRI, and laparoscopy. Results Classification of f...

  16. Uncommon manifestations of Endocervical Malignant Mixed Mullerian Tumor with Incidental Bilateral Fallopian Tube Carcinoma

    OpenAIRE

    Prasad, Kishan H. L.; Makannavar, J H; Shetty, Jayaprakash; Vinutha; Patil, Channappa; Permi, Harish S

    2011-01-01

    A 43-year-old perimenopausal lady presented with bleeding per vagina and lower abdominal pain. On evaluation, she had cervical polyp, which expelled spontaneously during the per speculum examination. Histopathology revealed malignant mixed Mullerian tumor. Extended hysterectomy with salphingo oophorectomy was carried out, which showed bilateral fallopian tube carcinoma and leiomyoma uterus. The patient was treated with carboplatin regime and found to be disease-free for 1 year. This case pres...

  17. An Unusual Case of Cervical Tuberculosis

    OpenAIRE

    Prashant. S. Joshi; Vijay Shankar S; Pushpee Sinha

    2011-01-01

    Tuberculosis of the cervix is a rare disease and accounts to 0.1 – 0.65% of all cases of tuberculosis and 5 – 24 % of genital tract tuberculosis. We present an unusual case of 40 years old lady who presented with irregular bleeding per vagina and foul smelling white discharge for 1 year. Per speculum examination revealed an unhealthy looking cervix which bled on touch. A clinical diagnosis of carcinoma cervix was made. However, cervix biopsy revealed granulomatous lesion suggestive of tubercu...

  18. Monogeneans of the malabar grouper Epinephelus malabaricus (Perciformes, Serranidae) off New Caledonia, with a description of six new species of Pseudorhabdosynochus (Monogenea: Diplectanidae)

    OpenAIRE

    Justine, Jean-Lou; Sigura, Aude

    2007-01-01

    Eleven species were differentiated among more than 300 monogeneans collected on the gills of two wild malabar groupers, Epinephelus malabaricus, caught in the lagoon of New Caledonia, South Pacific. Diplectanids included seven species of Pseudorhabdosynochus Yamaguti, 1958, which were differentiated mainly on the basis of morphology of the sclerotised vagina. P. manifestus n. sp. was the most abundant species (65–80% of the diplectanids); all other species were rare. It is characterised by mo...

  19. Characterization of biofilm-forming microorganisms isolated from vaginal exudate in Portugal

    OpenAIRE

    Alves, P.; Castro, J.de; Cereija, Tatiana Barros Reis; Henriques, Ana Filipa Frutuoso Mendes; Cerca, Nuno

    2012-01-01

    Bacterial vaginosis (BV) is one of the most common gynaecological conditions affecting women in the reproductive age, and can lead to increase risk gynaecological infections and pre-term labour. The aetiology of this pathology is still poorly understood, but recent reports referring to the presence of anaerobic biofilms both in the healthy and BV vagina (with different microbial compositions) have led to the theory that the microorganisms that form biofilms may be relevant for the aetiology o...

  20. Morfologia macroscópica do aparelho reprodutor feminino de Leontopithecus cativos (Lesson, 1840) Primates-Callitrichidae Gross morphology of the female genital tract of captive Leontopithecus (Lesson, 1840) Primates-Callitrichidae

    OpenAIRE

    L. Pissinatti; R. Tortelly; M. Porto; C.H.F. Burity; Pissinatti, A

    2008-01-01

    Descreveu-se o sistema reprodutor feminino em três espécies de mico-leão Leontopithecus (Lesson 1840), cativos: L. rosalia, L. chrysopygus e L. chrysomelas. A vulva está delimitada pelos lábios vulvares menores e com clitóris conspícuo. A superfície do períneo urogenital apresenta elevações papilares mais concentradas nos lábios vulvares, conferindo-lhe aspecto rugoso. O vestíbulo vaginal constitui um tubo muscular de parede espessa que se estende da rima da vulva até o óstio da vagina. A vag...

  1. The Human Vaginal Bacterial Biota and Bacterial Vaginosis

    OpenAIRE

    Sujatha Srinivasan; David N. Fredricks

    2008-01-01

    The bacterial biota of the human vagina can have a profound impact on the health of women and their neonates. Changes in the vaginal microbiota have been associated with several adverse health outcomes including premature birth, pelvic inflammatory disease, and acquisition of HIV infection. Cultivation-independent molecular methods have provided new insights regarding bacterial diversity in this important niche, particularly in women with the common condition bacterial vaginosis (BV). PCR met...

  2. Vesico-vaginal fistula and psycho-social well-being of Nigerian women

    OpenAIRE

    Fasakin, Gbola Jonathan

    2008-01-01

    The problem of vesico-vagina fistula still remains a ravaging scourge in resource-poor countries of which Nigeria is visibly prominent. A majority of the cases are attributed to prolonged complicated labour due to inaccessibility of adequate and immediate obstetric health care. Complicated labour arises as a result of narrow pelvis bones of victims due to suffering from poor nutrition. While the above factors are noted as the direct cause to the prevalent of VVF, there are other socio-cultura...

  3. [A neonate with ambiguous genitalia].

    Science.gov (United States)

    Jansen, Burgo J; van Rijn, Rick R; van Trotsenburg, A S P Paul

    2015-01-01

    In a neonate with ambiguous genitalia, physical examination revealed a phallus. Ultrasonography showed a vagina and uterus, but no gonads. Because of severe undervirilisation in the presence of a uterus, probably due to 46,XY gonadal dysgenesis, parents were advised female sex assignment. When after a few weeks the phallus had increased in size, abdominal laparoscopy showed an underdeveloped uterus. Gonadal biopsy confirmed gonadal dysgenesis. Sex assignment was reconsidered and changed into the male gender. PMID:26200425

  4. [The bacterial vaginosis--treatment problems].

    Science.gov (United States)

    Romanik, Ma?gorzata K; Ekiel, Alicja M; Tomana, Lidia; Martirosian, Gayane

    2007-01-01

    The changes in vaginal ecosystem (decreasing number of H2O2 producing Lactobacillus spp. and increasing number of Mobiluncus spp., Gardnerella vaginalis, Atopobium vaginae, Prevotella spp., Mycoplasma hominis, Peptostreptococcus spp.) appears to be a major cause of bacterial vaginosis (BV). Bacterial vaginosis is associated with infectious complications in pregnant and non-pregnant women and increasing risk of STI. The preventive role of natural vaginal microflora and problems of BV treatment are discussed in the light of the recent publications. PMID:17607971

  5. Pharmacomicrobiomics: The Impact of Human Microbiome Variations on Systems Pharmacology and Personalized Therapeutics

    OpenAIRE

    ElRakaiby, Marwa; Dutilh, Bas E.; Rizkallah, Mariam R; Boleij, Annemarie; Cole, Jason N.; Aziz, Ramy K

    2014-01-01

    The Human Microbiome Project (HMP) is a global initiative undertaken to identify and characterize the collection of human-associated microorganisms at multiple anatomic sites (skin, mouth, nose, colon, vagina), and to determine how intra-individual and inter-individual alterations in the microbiome influence human health, immunity, and different disease states. In this review article, we summarize the key findings and applications of the HMP that may impact pharmacology and personalized thera...

  6. Frequency Distribution Candidal Vaginitis in Women Referred to Health Centers in Yazd

    Directory of Open Access Journals (Sweden)

    Ali Fattahi Bafghi

    2014-11-01

    Full Text Available Introduction: The vaginal flora is a dynamic ecosystem that can be easily altered. Although, there are four causes of vaginal discharges which cover almost 95% of vaginaitis. Candidal Vaginaitis is an infection of the vagina’s mucous membranes by Candida albicans (CA. Present study attempted to Candidal Vaginitis in women referred to health centers in Yazd and the role of innate & cell-mediated immunity against Candidal Vaginitis. Materials and Methods: A cross-sectional study conducted from September 2011 to September 2012 in Yazd city. A total of 360 women were recruited. The collection of material for diagnosis is ideally performed during a comprehensive pelvic examination using a speculum for diagnosis of CA with identify vaginal pH; smear preparing and staining and culturing. Results: Finally all of 360 women that observed and tested, 120 (33.33% of them have involved and 240 (66.67% have not involved. from 120 infected women, 55paitents had Bacterial vaginosis (15.6% 40 patients had Ca (10.8% and 25 patients had Trichomonas vaginalis (5.9%. Despite the role for cell-mediated immunity in host protection against the majority of mucosal CA infections, studied has been in women with recurrent vaginitis, in HIV-infected women. Thus, current investigations have been focused specifically on innate and acquired immune responses against CA at the vaginal mucosa instead of Vulvovaginal Candidiasis being caused by defective or dysfunctional CD4+ T helper 1-type cell-mediated immune reactivity. Conclusion: Strongly suggest that distinct vaginal lymphocyte subsets participate in the adaptive anti-Candida immunity at the vaginal level, with the vaginal CD4_ T cells probably playing a major role.

  7. Human cervicovaginal fluid biomarkers to predict term and preterm labor

    OpenAIRE

    Heng, Yujing J.; Liong, Stella; Permezel, Michael; Rice, Gregory E; Di Quinzio, Megan K. W.; Georgiou, Harry M.

    2015-01-01

    Preterm birth (PTB; birth before 37 completed weeks of gestation) remains the major cause of neonatal morbidity and mortality. The current generation of biomarkers predictive of PTB have limited utility. In pregnancy, the human cervicovaginal fluid (CVF) proteome is a reflection of the local biochemical milieu and is influenced by the physical changes occurring in the vagina, cervix and adjacent overlying fetal membranes. Term and preterm labor (PTL) share common pathways of cervical ripening...

  8. Robotic repair of vesicovaginal fistulae with the transperitoneal-transvaginal approach: A case series

    Scientific Electronic Library Online (English)

    Luciano A. Nunez, Bragayrac; Raed A., Azhar; Golena, Fernandez; Marino, Cabrera; Eric, Saenz; Victor, Machuca; Robert de, Andrade; Oswaldo, Carmona; Rene, Sotelo.

    2014-12-01

    Full Text Available Objective To describe a novel technique of repairing the VVF using the transperitoneal-transvaginal approach. Materials and Methods From June 2011 to October 2013, four patients with symptoms of urine leakage in the vagina underwent robotic repair of VVF [...] with the transperitoneal-transvaginal approach. Cystoscopy revealed the fistula opening on the bladder. A ureteral stent was placed through the fistulous tract. After trocar placement, the omental flap was prepared and mobilized robotically. The vagina was identified and incised. The fistulous tract was excised. Cystorrhaphy was performed in two layers in an interrupted fashion. The vaginal opening was closed with running stitches. The omentum was interposed and anchored between the bladder and vagina. Finally, the ureteral catheters were removed in case they have been placed, and an 18 Fr urethral catheter was removed on the 14th postoperative day. Results The mean age was 46 years (range: 41 to 52 years). The mean fistula diameter was 1.5 cm (range 0.3 to 2 cm). The mean operative time was 117.5 min (range: 100 to 150 min). The estimated blood loss was 100 mL (range: 50 to 150 mL). The mean hospital stay was 1.75 days (range: 1 to 3 days). The mean Foley catheter duration was 15.75 days (range: 10 to 25 days). There was no evidence of recurrence in any of the cases. Conclusions The robot-assisted laparoscopic transperitoneal transvaginal approach for VVF is a feasible procedure when the fistula tract is identified by first intentionally opening the vagina, thereby minimizing the bladder incision and with low morbidity.

  9. Diagnosis of Ovarian Metastasis from Gestational Trophoblastic Neoplasia by 3D Power Doppler Ultrasound and Dynamic Contrast-Enhanced Magnetic Resonance Imaging: Case Report

    OpenAIRE

    Júnior, E. Araujo; Sun, S.Y.; Campanharo, F.F.; Nacaratto, D.C.; Nardozza, L.M.M.; Mattar, R.; Habib, V.V.; Moron, A.F.

    2012-01-01

    Choriocarcinoma is a highly malignant disease of trophoblastic cells, which affects young women in the reproductive years. The main sites of metastasis from choriocarcinoma are lung, vagina, liver, gastrointestinal tract and kidneys, and the involvement of the ovaries is extremely rare. The diagnosis of ovarian metastasis is made mainly by two-dimensional ultrasonography (2DUS) with color Doppler, which shows a large vessel in the center of the mass. The three-dimensional power Doppler ultras...

  10. Scrotal and penile reconstruction using the vacuum-assisted closure device

    OpenAIRE

    Snyder, Ned; Gould, Lisa J

    2005-01-01

    Fournier’s gangrene is a necrotizing, soft tissue infection that spreads along the deep external fascial planes of the perineum, scrotum (or vagina), penis, thighs and lower abdomen. Due to the rapid progression of the disease, patients are frequently left with a large integumentary deficit. Treatment of the skin defect has been described in a multitude of ways including split-thickness skin grafting, burying the testes in the thighs, thigh flaps and a variety of myocutaneous and fasciocutane...

  11. Variables seminales en llama (Lama glama) * Semen variables in llama (Lama glama)

    OpenAIRE

    L. VON BAER; C. HELLEMANN

    1998-01-01

    El objetivo del trabajo fue el ensayo de una técnica de colección de semen de llamas (Lama glama) con vagina artificial y el registro de variables seminales, tendiente a estudiar parámetros indicadores de la fertilidad potencial del macho. De 18 machos en edad reproductiva de un criadero se seleccionaron 11, de los cuales se obtuvieron 72 eyaculados. Descartados 31 eyaculados por azoospermia o akinozoospermia y 15 en que no se obtuvieron todos los registros, quedaron 26 eyaculados cuyas varia...

  12. Trachelectomy for cancer of the cervix: dargent's operation. Vaginal hysterectomy for early cancer of the cervix stage IA1 and CIN III

    DEFF Research Database (Denmark)

    Ottosen, Christian

    2011-01-01

    Radical vaginal trachelectomy is today an established method of treating selected women with cervical cancer stage IA2 and IB1, with tumour size less than 2cm without precluding future childbearing. This technique has been used for more than 20 years with reassuring oncological safety and excellent obstetrical outcomes. The procedure is a combination of laparoscopy for pelvic lymphadenectomy and challenging classic vaginal surgery to resect the tumour, part of the parametrium and upper vagina. C...

  13. Bilateral abscessed orchiepididymitis associated with sepsis caused by Veillonella parvula and Clostridium perfringens: case report and review of the literature.

    OpenAIRE

    Arrosagaray, P M; Salas, C.; M Morales; Correas, M; Barros, J M; Cordon, M L

    1987-01-01

    Veillonella species is a gram-negative coccus which is part of the anaerobic normal flora in the oral cavity, small intestine, upper respiratory tract, vagina, and urinary tract. The role that this organism plays in infection is not well known, and it is generally associated with other bacteria. We present a case of bilateral abscessed orchiepididymitis associated with septicemia due to Veillonella parvula and, later, to Clostridium perfringens, with the development of severe renal insufficie...

  14. Reproductive performance of totally confined sheep bred with semen extended in a lactose-egg yolk-glycerol buffer and stored at 5 degrees C.

    OpenAIRE

    Hackett, A J; Wolynetz, M. S.

    1982-01-01

    Two experiments were carried out in January and May 1975 to study reproductive performance (fertility, prolificacy and fecundity) of totally confined sheep synchronized for estrus. The main objective of the first experiment was to compare reproductive performance of ewes bred naturally to those bred by artificial insemination. Semen for artificial insemination was collected by either artificial vagina or electroejaculation and stored for up to 36 hours at 5 degrees C. A second objective was t...

  15. Development of a Sperm Preparation Method for Artificial Insemination in Rabbits

    OpenAIRE

    Hee Yi; Soo-Min Cho; Myeong-Kyu Park; Jin-Sik Cho; You-Seok Kim; Wook-Joon Yu; Jeong-Sup Hong; Hee-Jung Cho; Ho-Chul Shin

    2012-01-01

    A novel method of sperm preparation by direct collection from the cauda epididymis and vas deferens of male rabbits is suggested and validated for improved artificial insemination efficiency in rabbits. Although, conventional methods in which sperm for artificial insemination are prepared using an artificial vagina have been well established in many laboratories due to its benefits over natural mating, this new method eliminates the existing disadvantages of the conventional semen preparation...

  16. Treatment of peunomovaginitis in dairy cattle by caslick operation

    OpenAIRE

    S. N. Dehghani,; Yavari, M.; M. KAFI

    2011-01-01

    Pneumovagina is caused by faulty closure of the lips of vulva as results of poor conformation or traumatic injuries to the vagina due to abnormal handling of the fetus during delivery. The present study was carried out to describe the beneficial effects of caslick operation in cattle affected by pneumovaginitis and infertility syndrome. 27 Holstein dairy cattle were referred to the veterinary teaching hospital of the Shiraz Veterinary School affected by pnumovagina and repeat breeder syndrome...

  17. Cervicovaginal HPV Infection Before and After Hysterectomy: Evidence of Different Tissue Tropism for Oncogenic and Non-Oncogenic HPV Types in a Cohort of HIV-positive and HIV-negative Women

    OpenAIRE

    D'souza, Gypsyamber; BURK, Robert D.; Zhong, Ye; Minkoff, Howard; Massad, L Stewart; Xue, Xiaonan; Watts, D Heather; ANASTOS, Kathryn; Palefsky, Joel M.; LEVINE, Alexandra M.; COLIE, Christine; Castle, Philip E.; STRICKLER, Howard D.

    2012-01-01

    Human papillomavirus (HPV) is detected in nearly all cervical cancers and approximately half of vaginal cancers. However, vaginal cancer is an order of magnitude less common than cervical cancer, not only in the general population but also among women with HIV/AIDS. It is interesting therefore that recent studies found that HPV was common in both normal vaginal and cervical tissue, with higher prevalence of non-oncogenic HPV types in the vagina. In the current investigation, we prospectively ...

  18. VALIDEZ DE LA PRUEBA DE HISTERECTOMÍA VAGINAL EN PACIENTES CON INDICACIÓN DE VÍA ABDOMINAL MANDATORIA

    Directory of Open Access Journals (Sweden)

    Juan Riquelme P

    2010-01-01

    Full Text Available Objetivo: Evaluar la histerectomía vaginal en la resolución de patología uterina benigna, en casos que habitualmente se resuelven por histerectomía abdominal. Método: Estudio prospectivo en 68 pacientes sometidas a histerectomía vaginal en el Servicio de Ginecología del Hospital Claudio Vicuña, de San Antonio, entre junio de 2003 a junio de 2009. Son pacientes sin partos vaginales, algunas nuligestas, la mayoría con cicatrices de cesárea o historia de cirugía pélvica previa. Se separan en dos grupos, uno de dificultad moderada (DM (útero móvil, vagina >2 dedos de diámetro, fondos de saco bien conformados y otro de dificultad severa (DS (útero fijo, vagina Objective: To assess vaginal hysterectomy in benign uterine pathology resolution in cases who are usually resolved by abdominal hysterectomy. Method: We studied, prospectively, 68 patients that were operated by vaginal hysterectomy between june 2003 to june 2009 in the Gynecology Service at Claudio Vicuña Hospital, San Antonio. Most of the patients have history of prior cesarean section or pelvic surgery, but no one has had vaginal deliveries, inclusive, some of them, have no history of previous pregnancies. The patients were separated into two groups, moderate difficulty (MD: composed by patients with uterus conserved motility, vagina >2 fingers diameter, well conserved cul de sac, and severe difficulty (SD: composed by patients with none uterine motility, vagina <2 fingers diameter or fat cul de sac. Results: We did not observed statistically signifcant differences in age, number of prior cesarean sections or pelvic surgeries, estimated uterine size, bladder injury, nor abdominal conversion, but there was significant differences in operative time and need of morcelation, being greater in SD patients. It is important to notice the absent of major and minor complications in 93% of the patients. Conclusion: Our results are meant to demystify the objections for vaginal route, including the patients with extreme difficulty.

  19. Aggressive angiomyxoma of the vulva presenting as a pedunculated swelling

    Directory of Open Access Journals (Sweden)

    Mandal Shramana

    2008-04-01

    Full Text Available Aggressive angiomyxoma is a rare, locally aggressive soft tissue tumor that has high propensity for local recurrence. It involves mainly the pelvis, vulva, perineum, vagina and urinary bladder in adult women in the reproductive age. Considering its locally aggressive nature, appropriate management and long-term follow-up is necessary. We describe a case of a 22-year-old young pregnant patient presenting with a large pedunculated swelling on the left labia majora.

  20. Meeting the sexual and reproductive health needs of married adolescents in northern Nigeria

    OpenAIRE

    Olunloyo, A.O.

    2009-01-01

    BACKGROUND: Nigeria has one of the largest numbers of married adolescents in the world. In the predominantly Muslim Northern region of the country, about 70% of girls get married and start childbearing by the age of 18. Early marriage limits the social and development opportunities of married adolescents as well as exposes them to sexual and reproductive health problems which often result in grave consequences such as vesico vagina fistula, sexually transmitted diseases including HIV and deat...

  1. Nephrogenic adenoma arising from the urinary bladder: a case report

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Sun Hee; Lee, Sun Wha; Han, Woon Seup [Ewha Womans Univ. College of Medicine, Seoul (Korea, Republic of)

    2001-03-01

    Nephrogenic adenoma is a benign metaplastic lesion of the urinary tract occurring most frequently at the urinary bladder. It is very rare, especially in children. We describe the US, CT and MRI findings of nephrogenic adenoma arising from the urinary bladder in an 8-year-old girl who suffered rupture of the bladder, urethra and vagina after a traffic accident and whose condition was complicated by urethral stricture and vesicoureteral reflux.

  2. A Giant Gartner Duct Cyst Originating from the Uterine Cervix and Adjacent Myometrium: A Case Report

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Eun Hui; Hwang, Seong Su; Park, Soo Youn [Catholic University, Seoul (Korea, Republic of)

    2008-11-15

    Gartner duct cysts are relatively common congenital cysts in the anterolateral wall of the vagina. Most are small (less than 2 cm) and asymptomatic, but larger cysts may cause problems. We report a rare case of a giant Gartner duct cyst (7 cm) originating from the right lateral portion of the uterine cervix and adjacent myometrium. It appeared as an exophytic multiseptated cystic mass containing different density fluids on CT

  3. Female epispadias

    Directory of Open Access Journals (Sweden)

    M V Krishna Shetty

    2011-01-01

    Full Text Available Isolated female epispadias without bladder exstrophy is an extremely rare congenital anomaly. The symptoms of female epispadias are primary urinary incontinence and abnormal anatomical features. A 7-year-old girl presented with partial incontinence of urine. On physical examination, bifid clitoris and labia minora were seen. The vagina and hymen were normal. Voiding cystourethrogram showed no reflux. With the diagnosis of isolated female epispadias, single stage reconstruction of the urethra, labia minora and clitoris was performed.

  4. Tumor de la vulva, vulvectomía radical Vulvar tumor, total vulvectomy

    Directory of Open Access Journals (Sweden)

    Asbel Alfredo Vicente de la Cruz

    2011-09-01

    Full Text Available Los tumores de la vulva no son una rareza entre los cánceres que afectan a las féminas, pero tampoco son de los más frecuentes. Se presenta el caso de una mujer de 59 años, que en el año 2000 se le diagnostica carcinoma epidermoide del clítoris, en 2004 se vuelve a intervenir por recidiva tumoral, y en 2009 acude a nuestra consulta nuevamente y es cuando se decide realizarle vulvectomía y resección de vagina y todo el sistema ginecológico. Concluyó la intervención con una talla vesical extraperitoneal. El tumor se extiende hasta la porción inicial de la vagina y uretra. Se trata de un tumor maligno, bien diferenciado, que se ha comportado en una forma no habitual, con recidivas locales, cuando en apariencia el tumor había sido resecado en toda su extensión, y en esta última oportunidad, a pesar de ser un estadio avanzado, no hemos encontrado metástasis ni multicentricidad del tumor. La evolución posoperatoria fue sin complicaciones y se dio de alta al quinto día.The vulvar tumors are not uncommon among the different types of cancer involving females, but neither are the more frequent ones. This is the case of a female aged 59 that in 2000 is diagnosed with epidermoid carcinoma of clitoris, in 2004 is re-operated on by tumor relapse, and in 2009 she came again to our consultation and a vulvectomy, vagina resection and all gynecological system are carried out. Intervention concluded with an extraperitoneal vesical cutting. The tumor extends up to the initial portion of vagina and urethra. It is a malignant and well-differentiated tumor behaved in non habitual way with local relapses, when apparently the tumor was resected in all its extent, and in this last change, despite and advanced stage, there were neither tumor metastases nor multi-centralization. The postoperative course was free of complications receiving the discharge at fifth day.

  5. DISORDER OF SEX DEVELOPMENT: DESCRIPTION OF 2 CASES OF MALE PSEUDOHERMAPHRODITISM

    Directory of Open Access Journals (Sweden)

    C. Varetti

    2012-01-01

    Full Text Available Introduction. "Genetic errors" with malformations and hormonal alterations result in a broad spectrum of disorders of sexual identity difficult to classify for etiopathogenesis and anatomy. Male pseudohermaphroditism (PEM is the result of defects in masculinisation, persistence of mullerian ducts or genital malformations. In these patients, there is always a 46 XY karyotype, male gonads with the external genitalia and phenotype completely or partially female. The authors describe 2 cases of PEM. Patients and Methods. RS and HNA, 9 and 15 years old. Both had 46 XY karyotype and female phenotype with the presence of penile clitoris and small vagina. The urethral meatus was positioned at the base of the penile clitoris and upper vagina and testicles, were located at the proximal portion of the inguinal canal.Patients were subjected to MRI showing absence of uterus and ovaries. The endoscopy described a small vagina dead-end about 4-5 cm long. Complete resection of the vagina, bilateral orchiopexy, correction of perineal hypospadias with urethral tubulization, reconstruction of the scrotum, with the results of penoscrotal hypospadias were performed. Discussion. Sexual differentiation is the process between VII and XII weeks of gestational age leading to formation of male or female fetus from embryo potentially bisexual. Brain Code gender is bipolar: male or female. In the sexual disorders there is a discrepancy between anatomical sex and the brain code. Genital malformation with a direct mechanism (external genitalia and indirect (prenatal pathological imprinting on all the receptors of target organs may exacerbate the brain deterioration of the code resulting in disease patterns difficult to manage according psychological and surgical aspects. Conclusions. Pediatric Surgeon plays a key role in the treatment of genital anomalies. Valutation of pelvic-perineal anatomy is important for the choice of sexual phenotype and related surgical strategy. Early correction of genital abnormality may effectively prevent the child present psychological, behavioral onsequences and problems in family and society.

  6. Culling practices of Ontario cow-calf producers.

    OpenAIRE

    McDermott, J J; Allen, O B; Martin, S. W.

    1992-01-01

    This study describes the distribution of herd culling rates for 123 Ontario cow-calf herds maintaining individual animal records. Associations between culling and factors at both the individual and herd level were examined. In addition, the relative importance of individual animal and herd level influences on culling were investigated. The following individual cow culling risk factors: nonpregnancy, age, weaning weight index, calf outcome, abortion, prolapsed vagina, prolapsed uterus, calving...

  7. Longitudinal analysis of the vaginal microflora in pregnancy suggests that L. crispatus promotes the stability of the normal vaginal microflora and that L. gasseri and/or L. iners are more conducive to the occurrence of abnormal vaginal microflora

    OpenAIRE

    Temmerman Marleen; De Backer Ellen; Claeys Geert; Verhelst Rita; Verstraelen Hans; Vaneechoutte Mario

    2009-01-01

    Abstract Background Despite their antimicrobial potential, vaginal lactobacilli often fail to retain dominance, resulting in overgrowth of the vagina by other bacteria, as observed with bacterial vaginosis. It remains elusive however to what extent interindividual differences in vaginal Lactobacillus community composition determine the stability of this microflora. In a prospective cohort of pregnant women we studied the stability of the normal vaginal microflora (assessed on Gram stain) as a...

  8. Female circumcision: a risk factor in postpartum haemorrhage.

    Directory of Open Access Journals (Sweden)

    McSwiney M

    1992-07-01

    Full Text Available A major postpartum haemorrhage occurred in a patient with a previous history of female circumcision. Following assisted vaginal delivery 6 litre blood loss occurred as a result of tears to the vagina and perineum. The tears were sutured, followed by insertion of vaginal packs. Replacement fluid therapy was given. To reduce the incidence of tears and accompanying haemorrhage, it is advisable to perform two episiotomies viz. anterior and midline posterior or mediolateral.

  9. Mouse intravaginal infection with Trichomonas vaginalis and role of Lactobacillus acidophilus in sustaining infection.

    OpenAIRE

    McGrory, T; Garber, G E

    1992-01-01

    Recent work with a mouse model of Trichomonas vaginalis infection indicated that only 25% of mice harbor Lactobacillus spp. and that T. vaginalis infection rates fall rapidly after 7 days postinfection. In women infected with T. vaginalis, there is a disruption of the Lactobacillus population, which usually predominates. In an attempt to establish a better mouse intravaginal infection that resembles human disease, we established Lactobacillus acidophilus in estrogenized BALB/c mice. T. vagina...

  10. La découverte de l'amour par Hidi Xinu. Récit caxinaua

    Directory of Open Access Journals (Sweden)

    1999-01-01

    Full Text Available La littérature concernant la cosmologie caxinaua est assez connue, on propose néanmoins un récit jubilatoire qui raconte la découverte de l?amour par le personnage Xidi Xinu. Ce récit évoque le désespoir des Caxinaua qui prenaient le ?vagin? pour une méchante plaie. Malgré la connaissance de leur pharmacopée, ils n?arrivaient pas à la guérir. Cependant, un jour, l?un des Caxinaua, Hidi Xinu, a vu un couple de singes copuler et a compris la fonction du vagin : le réceptacle de l?amour, cutati. EL DESCUBRIMIENTO DEL AMOR POR HIDI SHINU. UNA NARRACIÓN CASHINAHUA. Aunque la literatura sobre la cosmología cashinahua es bastante conocida, proponemos aquí una alegre narración que cuenta el descubrimiento del amor por parte del personage Hidi Shinu. Esta narración evoca el desespero de los Cashinahua, quienes tomaban la vagina por una mala herida. A pesar de sus conocimientos farmacológicos, no lograban sanarla. Sin embargo, un día, uno de los Cashinahua vio copular a una pareja de micos y comprendió la función de la vagina: el receptáculo del amor, chutati. THE DISCOVERY OF LOVE BY HIDI SHINU. A CASHINAHUA TALE. The literature of the Cashinahua mythology is quite well known, thus I present an amusing tale about the discovery of love by the character Hidi Xinu. This tale reminds us of the despair of the Cashinahua who thought the vagina to be a very severe flesh wound. Regardless of their knowledge of pharmacopoeia, they could not heal her. However, one day, Hidi Xinu saw a couple of monkeys copulate and only then did he understand the function of the vagina: the chamber of love, chutati.

  11. Retroperitoneoscopic Nephrectomy for Treatment of a Case of Left Single Ectopic Ureter Accompanied by Dysplastic Kidney

    OpenAIRE

    Hara,Ryoei; Fujii,Tomohiro; Jo, Yoshimasa; Yokoyama, Teruhiko; Miyaji, Yoshiyuki; Nagai,Atsushi

    2011-01-01

    We report the case of a 7-year-old girl with a single ectopic ureter who was treated with retroperitoneoscopic nephrectomy for a chief complaint of urinary incontinence. Preoperative CT showed a contrasted dysplastic kidney of 1cm in the renal fossa and a left ureteral opening into the vagina. Retroperitoneoscopic left nephrectomy was conducted with opening of the lateroconal fascia to enable identification of the dysplastic kidney. No intraoperative complications were encountered. Urinary in...

  12. Tumor de la vulva, vulvectomía radical / Vulvar tumor, total vulvectomy

    Scientific Electronic Library Online (English)

    Asbel Alfredo, Vicente de la Cruz; Maribel Lissette, Vicente Medina; Ada Hilda, de la Concepción de la Peña.

    2011-09-01

    Full Text Available Los tumores de la vulva no son una rareza entre los cánceres que afectan a las féminas, pero tampoco son de los más frecuentes. Se presenta el caso de una mujer de 59 años, que en el año 2000 se le diagnostica carcinoma epidermoide del clítoris, en 2004 se vuelve a intervenir por recidiva tumoral, y [...] en 2009 acude a nuestra consulta nuevamente y es cuando se decide realizarle vulvectomía y resección de vagina y todo el sistema ginecológico. Concluyó la intervención con una talla vesical extraperitoneal. El tumor se extiende hasta la porción inicial de la vagina y uretra. Se trata de un tumor maligno, bien diferenciado, que se ha comportado en una forma no habitual, con recidivas locales, cuando en apariencia el tumor había sido resecado en toda su extensión, y en esta última oportunidad, a pesar de ser un estadio avanzado, no hemos encontrado metástasis ni multicentricidad del tumor. La evolución posoperatoria fue sin complicaciones y se dio de alta al quinto día. Abstract in english The vulvar tumors are not uncommon among the different types of cancer involving females, but neither are the more frequent ones. This is the case of a female aged 59 that in 2000 is diagnosed with epidermoid carcinoma of clitoris, in 2004 is re-operated on by tumor relapse, and in 2009 she came aga [...] in to our consultation and a vulvectomy, vagina resection and all gynecological system are carried out. Intervention concluded with an extraperitoneal vesical cutting. The tumor extends up to the initial portion of vagina and urethra. It is a malignant and well-differentiated tumor behaved in non habitual way with local relapses, when apparently the tumor was resected in all its extent, and in this last change, despite and advanced stage, there were neither tumor metastases nor multi-centralization. The postoperative course was free of complications receiving the discharge at fifth day.

  13. Perineal template techniques for interstitial implantation of gynecological cancers using the Paris system of dosimetry

    Energy Technology Data Exchange (ETDEWEB)

    Leung, S. (Peter MacCallum Cancer Institute, Melbourne Victoria (Australia))

    1990-09-01

    Since 1984, perineal template/needle techniques for interstitial implantation of gynecologic cancer-cervix, vagina, vulva-have been developed at the Peter MacCallum Cancer Institute. The Paris System of dosimetry has been used resulting in greater dose homogeneity, fewer needles and radioactive sources and considerable simplification and ease of implantation compared with comparable techniques developed in the United States. Principles and techniques of implantation are described in detail.

  14. {sup 18}F-Fluorodeoxyglucose PET/CT in a Patient with Esophageal and Genital Leiomyomatosis

    Energy Technology Data Exchange (ETDEWEB)

    An, Young Sil; Kim, Deog Yoon [Kyung Hee University, Seoul (Korea, Republic of)

    2009-12-15

    Diffuse esophageal leiomyomatosis is a rare benign tumor, which can be associated with leiomyoma in female genital tracts involving the uterus, vagina, and vulva. Alport syndrome, an inherited disorder that includes the kidneys, eyes, and sensorineural hearing loss, is also rarely associated with these multiple leiomyomatosis. In our case, {sup 18}F-fluoroseoxyglucose positron emission tomography/ computed tomography was used to distinguish esophageal and genital leiomyomatosis from malignant masses.

  15. Localization of 3H-estradiol in the reproductive organs of male and female baboons

    International Nuclear Information System (INIS)

    The uptake and retention of radiolabeled estradiol by both the male and female reproductive organs were examined in the baboon. Two male and two female baboons were injected intracardially with 1 microgram/kg body weight of 3H-estradiol and two animals, one male and one female, were injected with both labeled and 100 micrograms/kg body weight of unlabeled estradiol. One and a half hours after the injections, the animals were sacrificed and the uterus, cervix, vagina, oviduct, seminal vesicles, and prostate gland were removed and processed for autoradiography. The stratified squamous epithelia of the cervix and vagina demonstrated a light uptake of the label in the germinative, but not in the superficial cell layers. The columnar cells lining the oviduct and uterine glands were labeled, whereas the luminal epithelium of the uterus and the glandular epithelia of the seminal vesicles and prostate gland did not sequester the tritiated steroid. The interstitial cells of all the organs studied demonstrated a moderate to heavy uptake of the radioactivity, whereas the smooth muscle cells were lightly labeled except in the vagina, in which these cells displayed a moderate number of silver grains

  16. Cervical Cancer – A Review Article

    Directory of Open Access Journals (Sweden)

    Gunjan Jadon

    2012-07-01

    Full Text Available Cervical Cancer is malignant Carcinoma type of cancer originate in cervix region. The cervix is the narrow portion of the uterus where it joins with the top of the vagina. Most cervical cancers are squamous cell carcinomas, arising in the squamous (flattened epithelial cells that line the cervix. Adenocarcinoma, arising in glandular epithelial cells is the second most common type. Very rarely, cancer can arise in other types of cells in the cervix. Cancer refers to a class of diseases in which a cell or a group of cells divide and replicate uncontrollably, intrude into adjacent cells and tissues (invasion and ultimately spread to other parts of the body than the location at which they arose (metastasis (National Cancer Institute 2009. In cervical cancer, (cancer of the uterine cervix, cancer develops in the tissues of the cervix, which is a part of the female reproductive system. The cervix connects the upper body of the uterus to the vagina. The endocervix (the upper part which is close to the uterus is covered by glandular cells, and the ectocervix (the lower part which is close to the vagina is covered by squamous cells. The transformation zone refers to the place where these two regions of the cervix meet (American Cancer Society 2009.

  17. Pengaruh Tepung Teripang Pasir (Holothuria Scabra Terhadap Perilaku Seksual dan Kadar Testosteron Darah Mencit (Mus musculus

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    Sarifah Nurjanah

    2009-09-01

    Full Text Available Sea cucumber is generally believed as a natural material that can be used as a tonic food to increase man vitality. The aim of this study was to investigate the effect of sandfish powder on sexual behavior and blood testosterone level of male mice. Method applied in the study was laboratory experimental method. Mature male mice were treated with administration of sandfish powder with three dosage rate of steroid content (10, 30 and 50 ìg/100 g body weight during 12 days, whereas for control treatment were without hormone administration and with the metil testosterone administration. Parameters that were investigated were kissing vagina and mounting for sexual behavior and the blood testosterone level of male mice. It was found that administration of sandfish powder significantly give effect on the number of kissing vagina and mounting compared to control. Administration of 10 ìg/100 g body weight on male mice showed the highest sexual behavior with 25 kissing vagina for and 6 mounting for 30 minutes. Moreover, administration of sandfish powder increased the testosterone level in the male mice blood. This may due to the steroid contained in sandfish powder and nutrition value that increase mice libido. The study proved that the sandfish powder has a potential as a nature aphrodisiac.

  18. Patología vaginal: utilidad de la citología y la colposcopia como métodos diagnósticos

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    Yanyn Betzabe Uzcátegui

    2012-09-01

    Full Text Available Objetivo: Evaluar la citología y la colposcopia como métodos diagnósticos de patología vaginal. Métodos: Estudio prospectivo y descriptivo que incluyó 100 pacientes. Se realizó citología, colposcopia y biopsia dirigida o del tercio superior de vagina, cuando no había lesiones. Resultados: La edad media de las pacientes fue 37,7 años. Hubo patología vaginal en 81 pacientes: 19 (23,4.% neoplasias intraepiteliales vaginales I y 62 (76,5 % lesiones no neoplásicas, entre ellas 47 (75,8.% con infección por virus de papiloma humano y 15 (24,2 % con otras lesiones. Entre las 37 pacientes con cambios colposcópicos, 56,8 % tenían epitelio acetoblanco fino, 45,9 % de los cambios estaban en el tercio superior. Hubo 5 casos de lesiones multifocales. Dos citologías presentaron cambios por virus de papiloma humano. En 66 pacientes hubo cambios histológicos compatibles con infección por este virus, 19 con neoplasia. La sensibilidad y especificidad de la citología para lesiones neoplásicas intraepiteliales fue 0 % y 100 %, de la colposcopia 47 % y 78 % y de ambos 75 % y 16 %, respectivamente. Los factores de riesgo significativos para infección por virus de papiloma humano y neoplasia intraepitelial fueron: edad, patología cervical y vulvar previa, uso de anticonceptivos orales y tabaquismo. Existe asociación significativa entre patología cervical o vulvar y el diagnóstico de infección por virus de papiloma humano en vagina. Conclusiones: La citología no debe ser usada aisladamente como método de pesquisa de lesiones neoplásicas de la vagina; se recomienda asociarla a la colposcopia vaginal.

  19. Development of a Sperm Preparation Method for Artificial Insemination in Rabbits

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    Hee Yi

    2012-01-01

    Full Text Available A novel method of sperm preparation by direct collection from the cauda epididymis and vas deferens of male rabbits is suggested and validated for improved artificial insemination efficiency in rabbits. Although, conventional methods in which sperm for artificial insemination are prepared using an artificial vagina have been well established in many laboratories due to its benefits over natural mating, this new method eliminates the existing disadvantages of the conventional semen preparation. To compare the quality of sperm collected using an artificial vagina with that retrieved directly from the cauda epididymis, motion parameters of sperm were analyzed with a computer-assisted sperm analyzer. Additionally, after 20 adult females were inseminated artificially with sperm derived from the cauda epididymis, all live dams were subjected to caesarean section on day 28 of gestation and their fetuses were examined for external, visceral and skeletal abnormalities. All data were compared to those of dams impregnated by the traditional artificial insemination method in which the semen was prepared with an artificial vagina. No significant difference was observed in any criteria examined between the new and traditional preparation methods. This new method yields the possibility of collecting more sperm usable in artificial insemination and reducing the time required for sperm preparation. The results of this study indicate that sperm preparation from the cauda epididymis for artificial insemination was faster and more efficient for impregnating rabbits than the traditional method.

  20. Excretory urography and ultrasonography in the diagnosis of bilateral ectopic ureters in a foal

    International Nuclear Information System (INIS)

    A 7-week-old Appaloosa filly was admitted for persistent urinary incontinence since birth. Vaginal speculum examination revealed urine flowing from an opening in the right vaginal wall. Cytoscopy demonstrated that the ureters did not terminate at the bladder. The endoscope passed easily from the vagina directly into a dilated right ureter. An excretory urogram confirmed the vaginal termination of at least one ureter, based upon extensive filling of the vagina with contrast media in the absence of bladder filling. Bilateral hydroureter and dilated renal pelves were demonstrated both by excretory urography and by urtrasonography. Euthanasia was required by the owner in lieu of attempted surgical correction. At necroscopy, it was confirmed that the right ureter entered the vagina and the left ureter terminated at the urethra. The diagnosis of bilateral ectopic ureter in this foal was suggested by this history and clinical signs, supported by endoscopy and ultrasonography, and confirmed by excretory urography and necropsy. This case establishes the value of diagnostic imaging techniques in the antemortem diagnosis of ectopic ureter

  1. Pre-operative, post-operative and exclusive irradiation of endometrial adenocarcinoma

    International Nuclear Information System (INIS)

    Purpose: Surgery is the golden standard of treatment of endometrial carcinoma. The risk of central or vaginal recurrences justifies adjuvant treatment. Methods: Brachytherapy for endometrial adenocarcinoma is given commonly as pre- or post-operative treatment. In case of medical contro-indications for surgery brachytherapy can be applied as the only tratment. Experience of the anticancer center Alexis Vautrin in Nancy of the years 1975 to 1988 is evaluated. Iridium-192 low-dose-rate (LDR) wires were used. Results: Pre-operative brachytherapy was given with a vaginal mould applicator to 580 patients. The dose was 50 Gy at 0.5 cm below the surface of the vagina. The locoregional control rate was 93% after 5 years and the 5-year survival 82%. 139 patients received radiotherapy alone and no surgery. LDR-brachytherapy was given the upper third of the vagina and endometrium with an 'umbrella' applicator. The locoregional control rate was 83% after 5 years and the survival rate 55%. 117 patients received a post-operative brachytherapy of the vagina. The locoregional control rate was 93% after 10 years and the survival rate 65%. Conclusion: A pre- and post-operative radiotherapy results in a reduction of the vaginal relapse rate. The LDR afterloading technique with primary radiotherapy of endometrial adenocarcinoma leads to a locoregional control slightly interior. The treatment results compare favourably with the best of the literature. (orig.)

  2. Advanced topical drug delivery system for the management of vaginal candidiasis.

    Science.gov (United States)

    Johal, Himmat Singh; Garg, Tarun; Rath, Goutam; Goyal, Amit Kumar

    2016-02-01

    Vaginal candidiasis or vulvovaginal candidiasis (VC) is a common mucosal infection of vagina, mainly caused by Candida species. The major symptoms of VC are dyspareunia, pruritis, itching, soreness, vagina as well as vulvar erythema and edema. Most common risk factors that lead to the imbalance in the vaginal micro biota are the use of antibiotics, pregnancy, diabetes mellitus, immuno suppression as in AIDS or HIV patients, frequent sexual intercourse, spermicide and intra-uterine devices and vaginal douching. Various anti-fungal drugs are available for effective treatment of VC. Different conventional vaginal formulations (creams, gels, suppositories, powder, ointment, etc.) for VC are available today but have limited efficacy because of lesser residence time on vaginal epithelium due to self-cleansing action of vagina. So to overcome this problem, an extended and intimate contact with vaginal mucosa is desired; which can be accomplished by utilizing mucoadhesive polymers. Mucoadhesive polymers have an excellent binding capacity to mucosal tissues for considerable period of time. This unique property of these polymers significantly enhances retention time of different formulations on mucosal tissues. Currently, various novel formulations such as liposomes, nano- and microparticles, micro-emulsions, bio-adhesive gel and tablets are used to control and treat VC. In this review, we focused on current status of vaginal candidiasis, conventional and nanotechnology inspired formulation approaches. PMID:24959937

  3. Populations of Salmonella enteritidis in the Tissues of Reproductive Organs in Laying Hens After Oral Challenge: A Real-Time PCR Study

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    Shu-Xuan Deng

    2011-01-01

    Full Text Available The objective of this study was to determine the populations of Salmonella enteritidis (S. enteritidis in reproductive organs of laying hens after oral challenge. Researchers conducted serovar-specific Real-time PCR for S. enteritidis to detect the genomic DNA of S. enteritidis from laying hens at different time points. To validate these results, the Indirect Fluorescent Antibody (IFA technique was employed too. The results showed that S. enteritidis was consistently detected in all the samples. Vagina and uterus were positive at 20 h PI and the last organ to show a positive result was the largest and third largest preovulatory follicle at 32 h PI. The copy numbers of S. enteritidis DNA in each tissue reached a peak at 36-60 h PI with the vagina and uterus containing higher concentrations than other tissues. However, the number of bacteria started decreasing by 3-4 days and by 6 days, the concentration of S. enteritidis DNA was below the detection limits of the PCR assay except the vagina. In conclusion, the results provided insights into the S. enteritidis populations in the reproductive organs. This study will help in understanding the pathogenesis of S. enteritidis infection in vivo.

  4. Aplicación de los colgajos fasciocutáneos vulvoperineales en cirugía pediátrica: a propósito de un caso Application of vulvoperineal fasciocutaneous flaps in pediatric surgery: case report

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    S. Pérez Bertólez

    2008-09-01

    Full Text Available La incidencia de agenesia de vagina es de 1/4000- 10000 recién nacidas vivas. La causa más frecuente es el síndrome de Mayer-Rokitansky-Küster-Hauser. Presentamos un caso de reconstrucción vaginal con colgajos fasciocutáneos vulvoperineales de Málaga en una paciente pediátrica afecta de este síndrome, describiendo los pasos del procedimiento y las bases anatómicas en las que se fundamenta. Esta técnica permite la creación de una neovagina sensible, con una cobertura de excelente calidad, con un ángulo de inclinación fisiológico y natural y un axis anatómico correcto para la relación sexual; se realiza en un solo tiempo quirúrgico y con mínima morbilidad para la paciente. Su principal inconveniente es el crecimiento de pelo dentro de la vagina, aunque se atenúa con el tiempo debido a un fenómeno de atrofia folicular y metaplasia cutánea.The incidence of vaginal agenesis is 1/4000-10000 female alive newborns. The most frequent cause is Mayer-Rokitansky-Küster-Hauser syndrome. A technique for vaginal reconstruction using the vulvoperineal fasciocutaneous flaps (Malaga flaps in a pediatric patient affected of this syndrome is presented, describing the steps of the procedure and its anatomic basis. This technique allows the reconstruction of an excellent quality and sensible neovagina, with a physiologic inclination angle which allows the sexual intercourse, in one single stage operation and with minimal morbidity. The main inconvenient of this procedure is the hair growth inside the vagina, although it diminishes with the passage of time due to follicular atrophy and cutaneous metaplasy.

  5. Recurrent endometrial cancer: patterns of recurrent disease and assessment of prognosis

    Energy Technology Data Exchange (ETDEWEB)

    Sohaib, S.A. [Department of Radiology, Royal Marsden Hospital, London (United Kingdom); Houghton, S.L. [Department of Radiology, Royal Marsden Hospital, London (United Kingdom); Meroni, R. [Department of Academic Radiology, St Bartholomew' s Hospital, London (United Kingdom); Rockall, A.G. [Department of Academic Radiology, St Bartholomew' s Hospital, London (United Kingdom); Blake, P. [Department of Gynaecological Oncology, Royal Marsden Hospital, London (United Kingdom); Reznek, R.H. [Department of Academic Radiology, St Bartholomew' s Hospital, London (United Kingdom)

    2007-01-15

    Aim: To evaluate patterns of disease and identify factors predicting outcome in patients presenting with recurrent endometrial adenocarcinoma following primary surgery. Materials and methods: A retrospective review was performed of the imaging and clinical data in 86 patients (median age 66 years, range 42-88 years) presenting with recurrent endometrial adenocarcinoma following primary surgery. Results: Following primary surgery recurrent disease occurred within 2 years in 64% and within 3 years in 87%. Relapse was seen within lymph nodes in 41 (46%), the vagina in 36 (42%) the peritoneum in 24 (28%) and the lung in 21 (24%). Unusual sites of disease included spleen, pancreas, rectum, muscle and brain. Univariate survival analysis showed the factors significant for poor outcome were: multiple sites of disease, liver and splenic disease, haematogenous, peritoneal and nodal spread, poorly differentiated tumour, and early relapse. The presence of disease within the vagina, bladder or lung was not associated with poor prognosis. Multivariate analysis identified multiple sites of disease, liver and splenic metastases to be independent predictors of poor outcome. Conclusion: The most frequently observed sites of relapse are: lymph nodes, vagina, peritoneum and lung. Significant predictors of poor outcome in recurrent disease are multiple sites of disease and liver and splenic metastases.

  6. Important differences in nitric oxide synthase activity and predominant isoform in reproductive tissues from human and rat

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    Al-Hijji J

    2003-02-01

    Full Text Available Abstract For the extrapolation of data obtained from experimental animals to the human situation, it is important to know the similarities and differences between human and animal species. Some important characteristics of nitric oxide synthase (NOS in myometrium and vagina from human and rat were compared. NOS-activity was measured by the formation of 14C-citrulline from 14C-arginine and the expression of NOS isoforms was examined by Western blotting. NOS activity in human uterus and vagina was significantly lower than in the tissues from rat. In contrast to the rat where NOS activity was predominantly found in the cytosolic fractions, NOS activity in particulate and cytosolic fractions from both human myometrium and vagina was similar. Data from Western blots confirmed that eNOS and nNOS isoforms were concentrated in the particulate and cytosolic fractions, respectively. Estrogen treatment of rats resulted in a down regulation of uterine cytosolic NOS activity. A down regulation of NOS in the cytosolic fraction was also seen in the human pregnant myometrium as compared with the nonpregnant myometrium. The vaginal NOS activity was considerably higher than the uterus in both species. In spite of some clear-cut qualitative and other differences between human and rat tissues, there are some interesting similarities. Downregulation in pregnancy of human uterine NOS is probably due to, at least in part, the influence of estrogen and progesterone.

  7. Utility of vaginal and rectal contrast medium in MRI for the detection of deep pelvic endometriosis

    Energy Technology Data Exchange (ETDEWEB)

    Chassang, M.; Novellas, S.; Bloch-Marcotte, C.; Chevallier, P. [Hopital Archet 2, Service d' Imagerie Diagnostique et Interventionnelle, Centre Hospitalier Regional et Universitaire de Nice, 151 route de Saint Antoine de Ginestiere, B.P. 3079, Nice Cedex 3 (France); Delotte, J.; Bongain, A. [Hopital Archet 2, Service de Gynecologie-Obstetrique, Centre Hospitalier Regional et Universitaire de Nice, 151 route de Saint Antoine de Ginestiere, B.P. 3079, Nice Cedex 3 (France); Toullalan, O. [Hopital de Cannes, Service de Gynecologie, 15 avenue des Broussailles, B.P. 264, Cannes Cedex (France)

    2010-04-15

    To study the sensitivity of MRI performed utilising vaginal and rectal opacification with ultrasound gel in the detection of deep pelvic endometriosis. This was a prospective monocentric study. All patients evaluated by the gynaecologist for pelvic pain, endometriosis or infertility were included. Axial and sagittal T2-weighted images were performed both with and without vaginal and rectal opacification with ultrasound gel. Three radiologists, all blinded, interpreted the images with a minimum of 15 days between the two readings. MRI performance with and without vaginal and rectal opacification was evaluated by calculating sensitivity, specificity and both positive and negative predictive values. Seventy-eight patients were included. Among these, 31 patients had deep pelvic endometriosis of which 24 were confirmed by laparoscopy. Seventy-six locations of deep pelvic endometriosis were discovered on MRI. For the three reviewers there was a significant improvement in sensitivity between pre- and post-contrast MRI (p < 0.0002). Opacification of the vagina and rectum significantly improved the sensitivity of MRI for the detection of deep pelvic endometriosis by expanding the vagina and rectum, thus allowing better delineation of the pelvic organs. This was especially apparent for lesions localised to the vagina and rectovaginal septum. (orig.)

  8. Características anatómicas y fisiológicas de los músculos pélvicos en la coneja doméstica (Oryctolagus cuniculus

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    Yolanda Cruz

    2010-01-01

    Full Text Available En mamíferos, la musculatura estriada pélvica se ha relacionado con la regulación de funciones urinarias y poco se sabe de su participación en funciones reproductivas. Los objetivos del presente estudio fueron determinar las características anatómicas y la inervación de los músculos iliococcígeo y pubococcígeo de la coneja adulta, y caracterizar la actividad electromiográfica (EMG refleja en respuesta a la estimulación genital. Para ello se utilizaron técnicas quirúrgicas y electrofisiológicas. Los resultados muestran que el iliococcígeo y pubococcígeo son músculos bilaterales que se originan en el hueso iliaco; están inervados por ramas que emergen de S3 y S4; sus fibras musculares no se adhieren a las vísceras pélvicas, sino que discurren lateral a la vagina y al recto y se insertan en las vértebras sacras. Durante la estimulación de la piel del orificio vaginal y la vagina pélvica y perineal se presentó actividad EMG refleja en ambos músculos. La estimulación de la vagina abdominal no indujo respuesta EMG. La estimulación cervical produjo inhibición temporal en la actividad del iliococcígeo y pubococcígeo. Estos resultados contribuyen a las escasas descripciones anatómicas de la musculatura pélvica de la coneja que se encuentran en libros de texto y atlas; también sugieren que los músculos pélvicos iliococcígeo y pubococcígeo podrían activarse reflejamente durante procesos reproductivos, como la cópula y el parto.

  9. Genotyping of Streptococcus agalactiae (group B streptococci isolated from vaginal and rectal swabs of women at 35-37 weeks of pregnancy

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    Verhelst Rita

    2009-09-01

    Full Text Available Abstract Background Group B streptococci (GBS, or Streptococcus agalactiae, are the leading bacterial cause of meningitis and bacterial sepsis in newborns. Here we compared different culture media for GBS detection and we compared the occurrence of different genotypes and serotypes of GBS isolates from the vagina and rectum. Methods Streptococcus agalactiae was cultured separately from both rectum and vagina, for a total of 150 pregnant women, i directly onto Columbia CNA agar, or indirectly onto ii Granada agar resp. iii Columbia CNA agar, after overnight incubation in Lim broth. Results Thirty six women (24% were colonized by GBS. Of these, 19 harbored GBS in both rectum and vagina, 9 only in the vagina and 8 exclusively in the rectum. The combination of Lim broth and subculture on Granada agar was the only culture method that detected all GBS positive women. Using RAPD-analysis, a total of 66 genotypes could be established among the 118 isolates from 32 women for which fingerprinting was carried out. Up to 4 different genotypes in total (rectal + vaginal were found for 4 women, one woman carried 3 different genotypes vaginally and 14 women carried two 2 different genotypes vaginally. Only two subjects were found to carry strains with the same genotype, although the serotype of both of these strains was different. Eighteen of the 19 subjects with GBS at both sites had at least one vaginal and one rectal isolate with the same genotype. We report the presence of two to four different genotypes in 22 (61% of the 36 GBS positive women and the presence of identical genotypes in both sites for all women but one. Conclusion The combination of Lim broth and subculture on Granada medium provide high sensitivity for GBS detection from vaginal and rectal swabs from pregnant women. We established a higher genotypic diversity per individual than other studies, with up to four different genotypes among a maximum of 6 isolates per individual picked. Still, 18 of the 19 women with GBS from both rectum and vagina had at least one isolate from each sampling site with the same genotype.

  10. Our experience of the use of Martius method to eliminate the vesicovaginal fistula

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    Stanojevi? Dušan

    2004-01-01

    Full Text Available Sometimes after delivery, gynecological or other surgeries, radiological therapy, or destructions of vesico-vaginal septum due to the tumor or trauma, the unnatural communication between the bladder and vagina occurs. Those are fistulas that occur after the delivery (tocogenic caused by the prolonged delivery or some obstetrics operations 1,2. Some fistulas are high, coming from the fundus of the bladder, medium, if they come just behind the trigonum of the bladder, and low, if they are in the level of trigonum and the neck of the bladder3. The purpose of this paper is to show the operative technique of elimination of medium and low vesicovaginal fistula and the results of the treatment. Material and method The elimination of the vesicovaginal fistula by original Martius technique is done through vagina4. The catheter is inserted through the fistula(figure 1. Than the mucosis of the vagina is cut around the fistula and the vaginal wall is separated from the bladder. The catheter is pulled out and the fistula on the bladder is sown with resorptive stitches. Than the labia maiora nearer to the fistula is cut along from Mons Veneris to the middle and the lipoid tissue is taken with vascular pedicle Than the catheter is inserted in the bladder that should stay there for four weeks. This is the method we used to make surgery in twenty patients with vesicovaginal fistula. The first one had the fistula as the result of the Caesarean section. She was operated twice through the bladder without success. The second patient was a fourteen years old girl that cut herself on the glass and damaged anal sfincter, rectum, vagina and the bladder. The fistula appeared later in the level of trigonum of the bladder. The other eighteen patients got fistula after hysterectomy. All patients were treated as described above and fistulas disappeared. The first patient had another baby a year after the operation by Caesarean section. The other patients have regular miction (figure 4 and 5. Discussion and the conclusion Vesicovaginal fistula are serous complications, for the patients and for the doctors. The only treatment of the vesicovaginal fistula is surgical5,6,7. If any damage of the bladder occurs during any operation it should be treated immediately, otherwise the fistula will appear. The treatment depends of the localization of the fistula. Low fistulas and some medium and urethrovaginal fistulas should be approached through vagina and according to our experience Martius,s method is very efficient. The only important thing is when the fistula is detected to wait at least for two or three months for the fistula to "consolidate" and also to cure the infection.

  11. Prevención del prolapso genital en histerectomía abdominal utilizando los ligamentos redondos: Experiencia personal

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    Farith Atías

    2010-06-01

    Full Text Available Objetivo: Prevenir el prolapso de la cúpula vaginal, empleando una técnica peroperatoria que consiste en fijar la cúpula vaginal a los ligamentos redondos, en el momento de realizar la intervención. Métodos: Realizada la histerectomía, se procedió al cierre de la cúpula vaginal con puntos separados en número de 6 a 8 con material no absorbible, dependiendo de la amplitud de la vagina. Los cabos distales son utilizados para anudar horizontalmente los ligamentos redondos. La fijación de las dos paredes del extremo superior de la vagina, garantiza mayor estabilidad de la vagina y menor posibilidad de producir el prolapso de la cúpula y/o de las paredes anterior y posterior de la vagina. Ambiente: Servicio de Ginecología, Hospital Universitario de Caracas Resultados: Las 124 pacientes histerectomizadas y controladas anualmente en un lapso entre 2 y 27 años, con un promedio de 7 años, ninguna de ellas presentó prolapso de cúpula vaginal. Las histerectomías se realizaron en el ejercicio privado. En centros asistenciales públicos, es muy difícil hacer seguimiento y evaluar las pacientes, por razones múltiples. Conclusiones: La histerectomía ocupa el primer lugar de las intervenciones ginecológicas, esto obliga a realizar la suspensión y fijación de la cúpula vaginal y simultáneamente corregir la patología asociada del aparato genital. El procedimiento que hemos empleado tuvo resultados muy favorables. La calidad de vida de las mujeres intervenidas quirúrgicamente no se desmejoró, como suele suceder cuando se produce el prolapso de la cúpula vaginal.Objective: To prevent vaginal vault prolapse, using a preoperative technique to fix the vaginal vault to the round ligaments in total abdominal hysterectomy, and identify associated pathology in the genital area. Methods: After hysterectomy, we proceed to the closure of the vaginal vault with interrupted sutures with non-absorbable material, in number of 6-8, depending of the amplitude of the vagina, the distal ends are used to tie horizontally bilateral round ligaments. The setting of the two upper walls of the vagina, ensures greater stability of the vagina and lower possibility of occurrence of prolapse of the dome and/or the anterior and posterior vaginal walls. Setting: Servicio de Ginecologia, Hospital Universitario de Caracas Results: The 124 patients undergoing hysterectomy, checked annually over a period of time between 2 and 27 years, with an average of 7 years, neither had vaginal prolapse. Conclusion: Histerectomy is the firstone gynecological operation. It requires making the suspension and fixation of the vaginal vault and simultaneously correct the genital tract associated pathology. The procedure we used had very favorable results. We can not compare our results with other techniques, do to scarse national an international references. The quality of life of women surgically intervened did not deteriorated, as usually happens when there is prolapse of the vaginal vault.

  12. Patología vaginal: utilidad de la citología y la colposcopia como métodos diagnósticos

    Scientific Electronic Library Online (English)

    Yanyn Betzabe, Uzcátegui; María Carolina, Tovar; Coromoto Jacqueline, Lorenzo; Mireya, González.

    2012-09-01

    Full Text Available Objetivo: Evaluar la citología y la colposcopia como métodos diagnósticos de patología vaginal. Métodos: Estudio prospectivo y descriptivo que incluyó 100 pacientes. Se realizó citología, colposcopia y biopsia dirigida o del tercio superior de vagina, cuando no había lesiones. Resultados: La edad me [...] dia de las pacientes fue 37,7 años. Hubo patología vaginal en 81 pacientes: 19 (23,4.%) neoplasias intraepiteliales vaginales I y 62 (76,5 %) lesiones no neoplásicas, entre ellas 47 (75,8.%) con infección por virus de papiloma humano y 15 (24,2 %) con otras lesiones. Entre las 37 pacientes con cambios colposcópicos, 56,8 % tenían epitelio acetoblanco fino, 45,9 % de los cambios estaban en el tercio superior. Hubo 5 casos de lesiones multifocales. Dos citologías presentaron cambios por virus de papiloma humano. En 66 pacientes hubo cambios histológicos compatibles con infección por este virus, 19 con neoplasia. La sensibilidad y especificidad de la citología para lesiones neoplásicas intraepiteliales fue 0 % y 100 %, de la colposcopia 47 % y 78 % y de ambos 75 % y 16 %, respectivamente. Los factores de riesgo significativos para infección por virus de papiloma humano y neoplasia intraepitelial fueron: edad, patología cervical y vulvar previa, uso de anticonceptivos orales y tabaquismo. Existe asociación significativa entre patología cervical o vulvar y el diagnóstico de infección por virus de papiloma humano en vagina. Conclusiones: La citología no debe ser usada aisladamente como método de pesquisa de lesiones neoplásicas de la vagina; se recomienda asociarla a la colposcopia vaginal. Abstract in english Objective: To evaluate the colposcopy and cytology as vaginal pathology diagnostic methods. Methods: prospective and descriptive study involving 100 patients. Cytology, colposcopy and directed biopsy, or in the upper vagina third when there was no injuries, was conducted. Results: The average age of [...] the patients was 37.7 years. There was vaginal pathology in 81 patients: 19 (23.4 %) vaginal intraepithelial neoplasia I and 62 (76.5 %) injuries non neoplastic, including 47 (75.8.%) with infection by human papillomavirus and 15 (24.2 %) with other injuries. Among the 37 patients with colposcopy changes, 56.8 % had fine acetoblanco epithelium, 45.9 % of the changes were in the upper third. There were 5 cases of multifocal lesions. Two PAP submitted changes for human papillomavirus. In 66 patients there were histological changes consistent with infection by this virus, 19 with neoplasia. The sensitivity and specificity of cytology for intraepithelial neoplastic lesions was 0 % and 100 %, for the colposcopy 47 per cent and 78 per cent, and for both methods, 75 % and 16 %, respectively. Significant risk factors for infection of human papillomavirus and intraepithelial neoplasia were: age, prior cervical and vulvar disease, use of oral contraceptives and smoking. There is significant association between cervical or vulvar pathology and the diagnosis of infection of human papillomavirus in vagina. Conclusions: Cytology should not be used alone as a method of investigation of neoplastic lesions of the vagina; It is recommended to associate it with the vaginal colposcopy.

  13. MORPHOLOGICAL AND HISTOCHEMICAL ASPECTS OF THE LUMINAL OVIDUCTAL EPITHELIUM OF THE LAYING AND NONLAYING MUSCOVY DUCK (Cairina moschata, LINNEAUS, 1758) / ASPECTOS MORFOLOGICOS E HISTOQUIMICOS DEL EPITELIO LUMINAL DEL OVIDUCTO DE LA PATA SILVESTRE (Cairina moschata, LINNAEUS, 1785) DURANTE LOS PERIODOS DE POSTURA Y NO POSTURA

    Scientific Electronic Library Online (English)

    Joaquim, Evêncio-Neto; Liriane Baratella, Evêncio; Walter Kenji, Fukumoto; Manuel de Jesus, Simões.

    Full Text Available Fueron estudiadas la morfología y la histoquímica del epitelio luminal del oviducto de la pata silvestre (Cairina moschata, Linnaeus, 1785)durante los períodos de postura y no postura. Se utilizaron 6 ejemplares, 3 en postura y 3 en no-postura. Los resultados mostraron que el oviducto está desarroll [...] ado en el lado izquierdo y atrofiado en el lado derecho y que está constituido por seis regiones: fimbrias, infundíbulo, magno, itsmo, glándula de la cáscara y vagina. El oviducto es más evidente y desarrollado en la fase de postura. El epitelio de revestimiento es simple cilíndrico ciliado, excepto en la región de la vagina donde se presentó pseudoestratificado cilíndrico ciliado. En todas las porciones del oviducto se observaron células ciliadas y no ciliadas. En la fase de postura predominaban las células no ciliadas y en la fase de no postura, las ciliadas. En la región de las fimbrias y en la glándula de la cáscara se observa equilibrio entre los dos tipos celulares. Por histoquímica se comprobó que el epitelio superficial muestra reactividad positiva al PAS en infundíbulo, magno e itsmo (excepto en la fase de postura) y vagina. En fimbrias y cáscara no fueron observadas células mucosasen ninguna de las dos fases Abstract in english The authors have used three laying and three non-laying muscovy ducks (Cairina moschata, Linneaus, 1758), in order to study morphological and histochemical aspects of the luminal oviductal epithelium. The results showed that the oviduct of the muscovy duck is well-developed at the left side, atrophi [...] ed at the right side and consists of six different regions: fimbria, infundibulum, magnum, isthmus, shell-gland and vagina. The oviduct is more evident and developed in the laying phase of the reproductive period. The lining epithelium is of single cylindric ciliated type, with the exception of the region of the vagina, where it is of pseudo-stratified cylindric ciliated type. In all portions of the oviduct it was observed that the epithelium presents ciliated and non-ciliated cells. It was verified a predominance of non-ciliated cells in the laying period and of ciliated cells in the nonlaying period, with the exception of the regions of the fimbriae and shell-gland, where an equilibrium of these two cell-types is observed. With regard to the detection of mucous substances, it was noted that the surface oviductal epithelium showed positive reactivity to PAS in the infundibulum, magnum and isthmus, and to A.B. pH 2.5 and 0.5 in the infundibulum, magnum, isthmus (with the exception of the laying period) and vagina. It was not observed the presence of mucous cells in the fimbriae and shell-gland in both phases of the reproductive period

  14. Inverse planning and class solutions for brachytherapy treatment planning

    International Nuclear Information System (INIS)

    Brachytherapy or interventional radiooncology is a method of radiation therapy. It is a method, where a small encapsulated radioactive source is placed near to / in the tumour and therefore delivers high doses directly to the target volume. Organs at risk (OARs) are spared due to the inverse square dose fall-off. In the past years there was a slight stagnation in the development of techniques for brachytherapy treatment. While external beam radiotherapy became more and more sophisticated, in brachytherapy traditional methods have been still used. Recently, 3D imaging was considered also as the modality for brachytherapy and more precise brachytherapy could expand. Nowadays, an image guided brachytherapy is state-of-art in many centres. Integration of imaging methods lead to the dose distribution individually tailored for each patient. Treatment plan optimization is mostly performed manually as an adaptation of a standard loading pattern. Recently, inverse planning approaches have been introduced into brachytherapy. The aim of this doctoral thesis was to analyze inverse planning and to develop concepts how to integrate inverse planning into cervical cancer brachytherapy. First part of the thesis analyzes the Hybrid Inverse treatment Planning and Optimization (HIPO) algorithm and proposes a workflow how to safely work with this algorithm. The problem of inverse planning generally is that only the dose and volume parameters are taken into account and spatial dose distribution is neglected. This fact can lead to unwanted high dose regions in a normal tissue. A unique implementation of HIPO into the treatment planning system using additional features enabled to create treatment plans similar to the plans resulting from manual optimization and to shape the high dose regions inside the CTV. In the second part the HIPO algorithm is compared to the Inverse Planning Simulated Annealing (IPSA) algorithm. IPSA is implemented into the commercial treatment planning system. It has no additional features how to control spatial distribution of high dose regions. It is possible to create a dosimetrically acceptable treatment plans with IPSA. Nevertheless, the size of high dose regions is not acceptable. In comparison to manual treatment planning as well as to HIPO optimization, IPSA lead to the conflicting results concerning high dose regions. To be able to use IPSA for inverse treatment planning in cervical cancer brachytherapy additional tools have to be developed. The last part of the thesis is engaged with vaginal wall dosimetry. Dose volume constraints for target volume as well as for organs OARs are an input for inverse planning optimization calculation. A dose tolerance of each OAR has to be known to be able to create appropriate constraints. Until now only bladder, rectum and sigmoid were considered as OARs. The dose limits for vagina don't exist yet because of several uncertainties during assessing of dose to the vagina and vaginal morbidity. To overcome contouring uncertainties a simplified vagina contour was proposed and tested. The analysis showed that this contour is able to detect differences between different applicators as well as between different treatment plans. A prospective study comparing dosimetric results of this model and side effects in the vagina has to be done to prove whether this contour is working or not. In conclusion, this thesis proved that inverse planning can be used for cervical cancer brachytherapy. An appropriate implementation of the inverse planning algorithm has to be considered to avoid high dose regions. Prior including of a dose volume constrains of vagina as another input parameter for the inverse planning calculation vaginal dose reporting has to be solved. The feasibility of the proposed simplified vagina contour for dose reporting has to be proven with a prospective study. (author)

  15. Evaluación de la toxicidad vaginal de Croton lechleri en conejas / Assessment of Croton lechleri vaginal toxicity in rabbits

    Scientific Electronic Library Online (English)

    Salomón, Ayala; Juan, Rojas; David, Díaz; José, Juárez; Carlos, Delgado.

    2010-04-01

    Full Text Available Objetivo: Evaluar la toxicidad vaginal de una preparación en gel de Croton lechleri en conejas. Diseño: Estudio experimental. Institución: Centro de Investigación de Bioquímica y Nutrición Alberto Guzmán Barrón, Instituto de Investigaciones Clínicas, Instituto de Patología de la Facultad de Medicina [...] , y Facultad de Farmacia, Universidad Nacional Mayor de San Marcos, Lima, Perú. Material biológico: Resina de Croton lechleri y conejos hembras, blancos, Nueva Zelanda. Métodos: Los animales fueron distribuidos en tres grupos (n=5): I. Control, vehículo; II, C. lechleri 1%; y III, C. lechleri 5%; los conejos recibieron estas muestras en un volumen de 1 mL por vía intravaginal, una vez/día, durante 10 días consecutivos. Se observó el estado clínico general, así como la apariencia física de la vagina y el perineo por signos de flujo, eritema y edema. Al final del experimento se realizó la exéresis quirúrgica de la vagina de cada coneja y se evaluó macroscópicamente, buscando signos de irritación, sangrado o daño de la mucosa. Luego, se fijó en formol tamponado al 10% y posteriormente se tomó tres muestras representativas de las regiones cérvico-vaginal, media-vaginal, y urovaginal, para el estudio histopatológico. Principales medidas de resultados: Irritación vaginal. Resultados: El examen macroscópico de la vagina en el grupo control mostró aspecto congestivo leve en forma difusa, en todos los casos, y de aspecto similar en las muestras del grupo Croton lechleri al 1%. En la formulación al 5%, en dos casos se observó congestión petequial parcial leve. El estudio histopatológico reveló un puntaje promedio de irritación vaginal de 3,4 a 6 y 3,6 a 8 para las preparaciones al 1% y 5%, respectivamente. Conclusión: En nuestras condiciones experimentales, las preparaciones de gel de C. lechleri evaluadas fueron no irritantes para la mucosa vaginal y resultaron aceptables. Abstract in english Objective: To determine a Croton lechleri vaginal gel preparation toxicity in rabbits. Design: Experimental study. Setting: Alberto Guzman Barron Biochemistry and Nutrition Research Center, Clinical Research Institute, Institute of Pathology, Faculty of Medicine and Pharmacy Faculty, Universidad Nac [...] ional Mayor de San Marcos, Lima, Peru. Biological material: Croton lechleri resin and female white New Zealand rabbits. Methods: The animals were divided into three groups (n=5): I. Control, vehicle; II, C. lechleri 1%, and III, C. lechleri 5%; they received samples of 1 mL volume intravaginally 1 time/day for 10 consecutive days. The general clinical condition and physical appearance of the vagina and the perineum for signs of flow, erythema and edema were observed. At the end of the experiment surgical resection of the vagina of each rabbit was performed and signs of irritation, bleeding or mucosal damage were determined macroscopically. Specimens were placed in 10% buffered formalin and cervico-vaginal, mid-vaginal, and uro-vaginal samples underwent histopathology study. Main outcome measures: Vaginal irritation. Results: Gross examination of the vagina in both the control and the Croton lechleri 1% groups showed mild diffuse congestion. Two cases of Croton lechleri 5% formulation showed mild petechial congestion. Histopathology study revealed a vaginal irritation average score of respectively 3.4 to 6, and 3.6 to 8 for the 1% and 5% preparations. Conclusions: In our experimental conditions, gel preparations of C. lechleri evaluated were acceptable and not irritating to the vaginal mucosa.

  16. Patología vaginal: utilidad de la citología y la colposcopia como métodos diagnósticos

    Directory of Open Access Journals (Sweden)

    Yanyn Betzabe Uzcátegui

    2012-09-01

    Full Text Available Objetivo: Evaluar la citología y la colposcopia como métodos diagnósticos de patología vaginal. Métodos: Estudio prospectivo y descriptivo que incluyó 100 pacientes. Se realizó citología, colposcopia y biopsia dirigida o del tercio superior de vagina, cuando no había lesiones. Resultados: La edad media de las pacientes fue 37,7 años. Hubo patología vaginal en 81 pacientes: 19 (23,4.% neoplasias intraepiteliales vaginales I y 62 (76,5 % lesiones no neoplásicas, entre ellas 47 (75,8.% con infección por virus de papiloma humano y 15 (24,2 % con otras lesiones. Entre las 37 pacientes con cambios colposcópicos, 56,8 % tenían epitelio acetoblanco fino, 45,9 % de los cambios estaban en el tercio superior. Hubo 5 casos de lesiones multifocales. Dos citologías presentaron cambios por virus de papiloma humano. En 66 pacientes hubo cambios histológicos compatibles con infección por este virus, 19 con neoplasia. La sensibilidad y especificidad de la citología para lesiones neoplásicas intraepiteliales fue 0 % y 100 %, de la colposcopia 47 % y 78 % y de ambos 75 % y 16 %, respectivamente. Los factores de riesgo significativos para infección por virus de papiloma humano y neoplasia intraepitelial fueron: edad, patología cervical y vulvar previa, uso de anticonceptivos orales y tabaquismo. Existe asociación significativa entre patología cervical o vulvar y el diagnóstico de infección por virus de papiloma humano en vagina. Conclusiones: La citología no debe ser usada aisladamente como método de pesquisa de lesiones neoplásicas de la vagina; se recomienda asociarla a la colposcopia vaginal.Objective: To evaluate the colposcopy and cytology as vaginal pathology diagnostic methods. Methods: prospective and descriptive study involving 100 patients. Cytology, colposcopy and directed biopsy, or in the upper vagina third when there was no injuries, was conducted. Results: The average age of the patients was 37.7 years. There was vaginal pathology in 81 patients: 19 (23.4 % vaginal intraepithelial neoplasia I and 62 (76.5 % injuries non neoplastic, including 47 (75.8.% with infection by human papillomavirus and 15 (24.2 % with other injuries. Among the 37 patients with colposcopy changes, 56.8 % had fine acetoblanco epithelium, 45.9 % of the changes were in the upper third. There were 5 cases of multifocal lesions. Two PAP submitted changes for human papillomavirus. In 66 patients there were histological changes consistent with infection by this virus, 19 with neoplasia. The sensitivity and specificity of cytology for intraepithelial neoplastic lesions was 0 % and 100 %, for the colposcopy 47 per cent and 78 per cent, and for both methods, 75 % and 16 %, respectively. Significant risk factors for infection of human papillomavirus and intraepithelial neoplasia were: age, prior cervical and vulvar disease, use of oral contraceptives and smoking. There is significant association between cervical or vulvar pathology and the diagnosis of infection of human papillomavirus in vagina. Conclusions: Cytology should not be used alone as a method of investigation of neoplastic lesions of the vagina; It is recommended to associate it with the vaginal colposcopy.

  17. MORPHOLOGICAL AND HISTOCHEMICAL ASPECTS OF THE LUMINAL OVIDUCTAL EPITHELIUM OF THE LAYING AND NONLAYING MUSCOVY DUCK (Cairina moschata, LINNEAUS, 1758 ASPECTOS MORFOLOGICOS E HISTOQUIMICOS DEL EPITELIO LUMINAL DEL OVIDUCTO DE LA PATA SILVESTRE (Cairina moschata, LINNAEUS, 1785 DURANTE LOS PERIODOS DE POSTURA Y NO POSTURA

    Directory of Open Access Journals (Sweden)

    Joaquim Evêncio-Neto

    1997-01-01

    Full Text Available The authors have used three laying and three non-laying muscovy ducks (Cairina moschata, Linneaus, 1758, in order to study morphological and histochemical aspects of the luminal oviductal epithelium. The results showed that the oviduct of the muscovy duck is well-developed at the left side, atrophied at the right side and consists of six different regions: fimbria, infundibulum, magnum, isthmus, shell-gland and vagina. The oviduct is more evident and developed in the laying phase of the reproductive period. The lining epithelium is of single cylindric ciliated type, with the exception of the region of the vagina, where it is of pseudo-stratified cylindric ciliated type. In all portions of the oviduct it was observed that the epithelium presents ciliated and non-ciliated cells. It was verified a predominance of non-ciliated cells in the laying period and of ciliated cells in the nonlaying period, with the exception of the regions of the fimbriae and shell-gland, where an equilibrium of these two cell-types is observed. With regard to the detection of mucous substances, it was noted that the surface oviductal epithelium showed positive reactivity to PAS in the infundibulum, magnum and isthmus, and to A.B. pH 2.5 and 0.5 in the infundibulum, magnum, isthmus (with the exception of the laying period and vagina. It was not observed the presence of mucous cells in the fimbriae and shell-gland in both phases of the reproductive periodFueron estudiadas la morfología y la histoquímica del epitelio luminal del oviducto de la pata silvestre (Cairina moschata, Linnaeus, 1785durante los períodos de postura y no postura. Se utilizaron 6 ejemplares, 3 en postura y 3 en no-postura. Los resultados mostraron que el oviducto está desarrollado en el lado izquierdo y atrofiado en el lado derecho y que está constituido por seis regiones: fimbrias, infundíbulo, magno, itsmo, glándula de la cáscara y vagina. El oviducto es más evidente y desarrollado en la fase de postura. El epitelio de revestimiento es simple cilíndrico ciliado, excepto en la región de la vagina donde se presentó pseudoestratificado cilíndrico ciliado. En todas las porciones del oviducto se observaron células ciliadas y no ciliadas. En la fase de postura predominaban las células no ciliadas y en la fase de no postura, las ciliadas. En la región de las fimbrias y en la glándula de la cáscara se observa equilibrio entre los dos tipos celulares. Por histoquímica se comprobó que el epitelio superficial muestra reactividad positiva al PAS en infundíbulo, magno e itsmo (excepto en la fase de postura y vagina. En fimbrias y cáscara no fueron observadas células mucosasen ninguna de las dos fases

  18. FEMALE PSEUDOHERMAPHRODITISM

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    AL. Bulotta

    2012-01-01

    Full Text Available Introduction. 21?-hydroxylase deficiency is the most frequent cause of virilization in patients with female karyotype due to exposure of a female fetus to excess of androgen. We report anatomical and cosmetic results of feminizing genital reconstruction of two related patients (second cousin with XX karyotype born with urogenital sinus anomalies (UGS and not treated at birth. Materials and Metods. Patient 1 is 6-years old with ambiguous genitalia graded as Prader V and never undergone therapy or surgery. Patient 2 is 10-years old, graded as Prader IV and subjected to hormonal therapy and clitoral amputation at the age of 6. Mobilization of urogenital sinus, pull-through of vagina and tubulization of urethra was performed in both after placement of Foley chateters in vagina and bladder by cisto-vaginoscopy. Genitoplasty involved refashioning the tissues to create minora and majora labia and, after removal of corpora, partial clitorectomy was carried in patient 1 and clitoridal reconstruction in patient 2. Result. Vaginal introitus was positioned in the vestibule region below urethral meatus. Foley chateters was removed after two weeks in narcosis and the cosmetic and anatomic result was good. Conclusion. Goals of feminizing genitoplasty are to restore, soon as possible, anatomy achieving a more feminine appareance with a vagina for menstruation, to preserve reproductive capacity and to prevent urological sequelae but it’s also important to contribute in a development of a more stable gender identity. This procedure in two stage, based on an accurate diagnosis, is good to create feminine genital appareance in children with female pseudohermaphroditism expecially if not treated at birth.

  19. pH ?rodowiska pochwy i mikroskopia fazowo-kontrastowa rozmazów cytologicznych u kobiet po menopauzie

    Directory of Open Access Journals (Sweden)

    Marta B?aszczak

    2011-06-01

    Full Text Available Taking into account the fact that so far the boundary value of the maturation index (MI, above which hypoestrogenism in the organism can be found with absolute certainty, has not been unambiguously determined and that such a boundary has also not been determined for the pH of the vaginal environment, it was decided to find out how the values of the mentioned indices behave in women at different periods after the menopause. We also decided to determine how the Lactobacillus vaginalis bacteria behave at different periods after the menopause. The investigation was conducted in 114 women in total. The vaginal pH was assessed using colorimetric indicator strips (Merck, Germany. After collecting the vaginal smears both the maturation indices of the epithelial cells and the behaviour of Lactobacillus bacteria were appraised under the phase-contrast microscope, and the number of bacteria was determined using a Nugent scale. The analyses of the results of our research permit the following conclusions: 1. The inspection of vaginal smears using phase-contrast microscopy is a fast and precise way of quantitative assessment of the behaviour of different kinds of stratified squamous epithelium of the vagina and the degree of colonization of the vagina with the acid-forming bacteria Lactobacillus vaginalis. 2. The finding that more than 15% of cells originated from the basal layer and no more than 7% from the surface of the stratified epithelium in the vaginal smears and that the values of acidity of the vaginal environment are above pH 5 is characteristic for women more than five years after the onset of the menopause.3. In the course of aging of the women as the years go by, starting from 5 years after menopause, the normal forms of Lactobacillus vaginalis tended to disappear and only the polymorphic and involution forms lived in the vagina, and a complete lack of them was revealed in the senior women (more than 25 years after the menopause.

  20. Traumatismo encefalocraneano fetal por vía penetrante transvaginal / Transvaginal penetrating fetal head injury

    Scientific Electronic Library Online (English)

    Luis Rafael, Moscote Salazar; Gabriel, Alcalá-Cerra; Sandra Milena, Castellar Leones; Juan José, Gutiérrez Paternina.

    2012-10-01

    Full Text Available Los traumatismos encefalocraneanos in útero son extremadamente raros y suelen ser consecuencia de lesiones penetrantes a través de la pared torácica o abdominal, que alcanzan la cavidad uterina. Los originados a través de la vagina se han comunicado excepcionalmente. Se presenta el caso de un feto q [...] ue padeció traumatismo encefalocraneano penetrante, con fractura de la bóveda craneal y hemorragia intraventricular tras la introducción violenta de un objeto contundente a través de la vagina por parte de su madre. La ruptura traumática de las membranas ovulares desencadenó el trabajo de parto pretérmino. Tras el nacimiento, se realizó tratamiento quirúrgico de la fractura deprimida y desbridamiento de la herida; sin embargo, el paciente falleció cuatro semanas más tarde a causa de sepsis neonatal. El tratamiento de estos casos no solo deber ser dirigido a la corrección de las lesiones traumáticas primarias sino también a la prevención de las complicaciones infecciosas. Abstract in english In utero head traumas are extremely rare and are usually caused by penetrating injuries in the thoracic or abdominal wall that affect the uterine cavity. Transvaginal fetal head injuries have been reported in exceptional cases. This is a case-report of a fetus affected by penetrating head trauma wit [...] h skull fracture and intra-ventricular hemorrhage after his mother's self-insertion of a blunt object, violently through the vagina. Trauma disrupted the integrity of intrauterine membranes and precipitated preterm labor. After birth, there was a debridement of the scalp and surgical management of the fracture was performed; nevertheless, the patient died four weeks later, due to neonatal sepsis. Management of these wounds must not only be focused on repairing the primary wound, but on preventing the infectious complications.

  1. High Dose-Rate Intracavitary Brachytherapy for Cervical Carcinomas With Lower Vaginal Infiltration

    International Nuclear Information System (INIS)

    Purpose: This report presents the clinical applications of an automated treatment-planning program of high-dose-rate intracavitary brachytherapy (HDR-ICBT) for advanced uterine cervical cancer infiltrating the parametrium and the lower vagina. Methods and Materials: We adopted HDR-ICBT under optimized dose distribution for 22 cervical cancer patients with tumor infiltration of the lower half of the vagina. All patients had squamous cell carcinoma with International Federation of Gynecology and Obstetrics clinical stages IIB-IVA. After whole pelvic external beam irradiation with a median dose of 30.6 Gy, a conventional ICBT was applied as 'pear-shaped' isodose curve. Then 3-4 more sessions per week of this new method of ICBT were performed. With a simple determination of the treatment volume, the cervix-parametrium, and the lower vagina were covered automatically and simultaneously by this program, that was designated as 'utero-vaginal brachytherapy'. The mean follow-up period was 87.4 months (range, 51.8-147.9 months). Results: Isodose curve for this program was 'galaxy-shaped'. Five-year local-progression-free survival and overall survival rates were 90.7% and 81.8%, respectively. Among those patients with late complications higher than Grade 2 Radiation Therapy Oncology Group/European Organization for Research and Treatment of Cancer morbidity score, only one (4.5%) developed severe proctitis. Conclusions: Because of the favorable treatment outcomes, this treatment-planning program with a simplified target-volume based dosimetry was proposed for cervical cancer with lower vaginal infiltration

  2. Dor abdominal e retenção urinária aguda em adolescente apresentação clínica de hematocolpos e revisão da literatura / Adolescent with abdominal pain and acute urinary retention: clinical presentation of hematocolpos and review of the literature

    Scientific Electronic Library Online (English)

    Helena, Sousa; Helena, Fonseca; Lurdes, Sampaio.

    2010-09-01

    Full Text Available Introdução: O hematocolpos é uma patologia rara resultante da acumulação vaginal de sangue menstrual nas jovens com hímen imperfurado. Caso clínico: Adolescente de 13 anos e 11 meses, sexo feminino, previamente saudável, que recorreu ao serviço de urgência por dor abdominal e lombar, tenesmo e reten [...] ção urinária aguda. Ausência de menarca. Ao exame objectivo: estádio pubertário IV de Tanner, distensão abdominal e massa pélvica. O exame ginecológico revelou membrana himeneal azulada e proeminente. A ecogra?a pélvica evidenciou globo vesical muito exuberante, acumulação de ?uido ecogénico na vagina e hímen imperfurado. A himenectomia de urgência, efectuada poucas horas depois, decorreu sem intercorrências. Clinicamente bem na reavaliação um mês pós-operatório. Conclusão: Numa adolescente com amenorreia primária e dor abdominal ou retenção urinária aguda, o hematocolpos é um diagnóstico a colocar. A avaliação do estádio pubertário e história menstrual deve ser incluída nas consultas de rotina. Abstract in english Introduction: Hematocolpos in adolescents with imperforate hymen resulting from vaginal blood accumulation is a quite rare pathology. Case report: A previously healthy almost 14-year-old girl, was admitted to the emergency department with lower abdominal pain and acute urinary retention. No previous [...] menstruation. Objective examination with pubertal Tanner stage IV, abdominal distension and pelvic mass. Gynecological examination revealed a blue imperforate hymen bulging from the vagina introitus outwards. Ultrasonography showed exuberant vesical globe and echogenic ?uid accumulation in the vagina. Cruciate hymenotomy was un­eventful. Asymptomatic in the follow-up, one month later. Conclusion: The diagnosis of imperforate hymen and hematocolpos is probable in an adolescent girl with primary amenorrhea, abdominal pain or acute urinary retention. Evaluation of the pubertal stage and menses should be included in routine practice.

  3. Comparison of effects of estradiol (E2) with those of octylmethoxycinnamate (OMC) and 4-methylbenzylidene camphor (4MBC) - 2 filters of UV light - on several uterine, vaginal and bone parameters

    International Nuclear Information System (INIS)

    OMC and 4MBC are 2 absorbers of ultraviolet light which are used in unknown quantities in sunscreens, cosmetics and plastic products to protect against UV light-induced damage of the skin or of fragrances or plastic material. From there, they were shown to reach surface water and/or by direct contamination or ingestion the human. Under various conditions in mice and rats, both substances were shown to be estrogenic. Therefore, we compared in vitro and in vivo the effects of chronic application of these compounds at 2 doses with those of E2, all administered via food. No signs of toxicity were observed under application of 0.6 mg E2, 57.5 or 275 mg of OMC, 57.5 or 250 mg of 4MBC; these amounts were ingested with 21 g of control food, 17.8 g E2 food, 20.6 g or 22.3 g OMC food and 23.7 or 22.8 g 4MBC food. In the uterus, vagina and bone, E2 exerted the expected stimulatory effects which were minimally shared by OMC and 4MBC in the uterus and vagina as assessed by histology and determination of a variety of estrogen-regulated genes such as insulin-like growth factor-1, progesterone receptor and estrogen receptor ?. In the bone, OMC had no effect, while 4MBC shared the antiosteoporotic effects of E2 as measured by quantitative computer tomography in the metaphysis of the tibia. The mechanism of action of 4MBC, however, appears to be different as E2 reduced serum osteocalcin and the C-terminal breakdown products of collagen-1?1 which were both increased by 4MBC. Taken together, these data indicate a very weak estrogenic effect of OMC and 4MBC in the uterus and in the vagina but not in the bone where 4MBC exerted antiosteoporotic effects by a different mechanism than E2

  4. Induction of avian ?-defensins by CpG oligodeoxynucleotides and proinflammatory cytokines in hen vaginal cells in vitro.

    Science.gov (United States)

    Sonoda, Yuka; Abdel Mageed, Ahmad M; Isobe, Naoki; Yoshimura, Yukinori

    2013-06-01

    Immune function in the vagina of hen oviduct is essential to prevent infection by microorganisms colonizing in the cloaca. The aim of this study was to determine whether CpG oligodeoxynucleotides (CpG-ODN) stimulate the expression of avian ?-defensins (AvBDs) in hen vaginal cells. Specific questions were whether CpG-ODN affects the expression of AvBDs and proinflammatory cytokines and whether the cytokines affect AvBDs expression in vaginal cells. The dispersed vaginal cells of White Leghorn laying hens were cultured and stimulated by different doses of lipopolysaccharide (LPS), CpG-ODN, interleukin 1? (IL1B), or IL6. The cultured cell population contained epithelial cells, fibroblast-like cells, and CD45-positive leukocytes. The immunoreactive AvBD3, -10, and -12 were localized in the mucosal epithelium in the section of the vagina. The expression of AvBDs, IL1B, and IL6 was analyzed by quantitative RT-PCR. RT-PCR analysis showed the expression of AvBD1, -3, -4, -5, -10, and -12 in the cultured vaginal cells without stimulation. Toll-like receptors (TLRs) 4 and 21, which recognize LPS and CpG-ODN respectively and IL1 and IL6 receptors (IL1R1 and IL6R) were also expressed in them. The expression of IL1B, IL6, and AvBD10 and -12 was upregulated by LPS, whereas only IL1B and IL6 were upregulated by CpG-ODN. IL1B stimulation upregulated AvBD1 and -3 expression, whereas IL6 stimulation did not cause changes in AvBDs expression. These results suggest that CpG-ODN derived from microbes upregulates the expression of IL1B and IL6 by interaction with TLR21 and then IL1B induces AvBD1 and -3 to prevent infection in the vagina. PMID:23625580

  5. Vicisitudes de un sencillo inventor / Vicissitudes of a humble inventor

    Scientific Electronic Library Online (English)

    Francisco, García López.

    2007-10-01

    Full Text Available Procedimiento mecanizado para el tratamiento de la Incontinencia Urinaria de Esfuerzo en la mujer. Fijación retropúbica de la vagina con una grapa disparada con grapadora diseñada con la forma apropiada, que utiliza la sínfisis del pubis como lugar de anclaje. Se pretende demostrar la razón fisiopat [...] ológica para devolver la continencia, por medio del anclaje de la uretra. En nuestras condiciones elementales de investigación y desarrollo no se pudo llegar a diseñar el procedimiento idóneo, aunque se presentó la idea mecanizada a Empresas de ámbito internacional. Se relata resumidamente el desarrollo del instrumento hasta conseguir hacerlo operativo, filmándose una intervención que se presentó al Congreso Hispanoamericano que se realizó en Madrid en 1992. El instrumento se patentó en la Oficina Española de Patentes y Marcas en julio de 1992 con categoría de Patente de Invención, al no existir antecedentes de procedimientos mecanizados para la fijación de la uretra a través de la vagina. Abstract in english Mechanized procedure for the treatment of female stress urinary incontinence. Retropubic fixation of the vagina with a stapler specifically designed, using the pubis’ symphysis as the site for anchoring. We intend to demonstrate the physiopathologic rationale to achieve continence by anchoring the u [...] rethra. In our elementary conditions for research and development we could not design the suitable procedure, although the idea was presented to international companies. We summarize the development of the instrument until it was operative, filming one operation which was presented to the Hispanic-American Congress in Madrid 1992. The instrument was patented in the Spanish Office of Patents and Trademarks in July 1992 with the category of invention patent because there were no previous mechanized procedures for vaginal fixation.

  6. A Pilot Study Measuring the Distribution and Permeability of a Vaginal HIV Microbicide Gel Vehicle Using Magnetic Resonance Imaging, Single Photon Emission Computed Tomography/Computed Tomography, and a Radiolabeled Small Molecule.

    Science.gov (United States)

    Fuchs, Edward J; Schwartz, Jill L; Friend, David R; Coleman, Jenell S; Hendrix, Craig W

    2015-11-01

    Vaginal microbicide gels containing tenofovir have proven effective in HIV prevention, offering the advantage of reduced systemic toxicity. We studied the vaginal distribution and effect on mucosal permeability of a gel vehicle. Six premenopausal women were enrolled. In Phase 1, a spreading gel containing (99m)technetium-DTPA ((99m)Tc) radiolabel and gadolinium contrast for magnetic resonance imaging (MRI) was dosed intravaginally. MRI was obtained at 0.5, 4, and 24?h, and single photon emission computed tomography with conventional computed tomography (SPECT/CT) at 1.5, 5, and 25?h postdosing. Pads and tissues were measured for activity to determine gel loss. In Phase 2, nonoxynol-9 (N-9), containing (99m)Tc-DTPA, was dosed as a permeability control; permeability was measured in blood and urine for both phases. SPECT/CT showed the distribution of spreading gel throughout the vagina with the highest concentration of radiosignal in the fornices and ectocervix; signal intensity diminished over 25?h. MRI showed the greatest signal accumulation in the fornices, most notably 1-4?h postdosing. The median (interquartile range) isotope signal loss from the vagina through 6?h was 29.1% (15.8-39.9%). Mucosal permeability to (99m)Tc-DTPA following spreading gel was negligible, in contrast to N-9, with detectable radiosignal in plasma, peaking at 8?h (5-12). Following spreading gel dosing, 0.004% (0.001-2.04%) of the radiosignal accumulated in urine over 12?h compared to 8.31% (7.07-11.01%) with N-9, (p=0.043). Spreading gel distributed variably throughout the vagina, persisting for 24?h, with signal concentrating in the fornices and ectocervix. The spreading gel had no significant effect on vaginal mucosal permeability. PMID:26077739

  7. Aplicación de los colgajos fasciocutáneos vulvoperineales en cirugía pediátrica: a propósito de un caso / Application of vulvoperineal fasciocutaneous flaps in pediatric surgery: case report

    Scientific Electronic Library Online (English)

    S., Pérez Bertólez; N., García Soldevilla; O., Maderna Graciano; F., Camacho González; A., Primelles Díaz.

    2008-09-01

    Full Text Available La incidencia de agenesia de vagina es de 1/4000- 10000 recién nacidas vivas. La causa más frecuente es el síndrome de Mayer-Rokitansky-Küster-Hauser. Presentamos un caso de reconstrucción vaginal con colgajos fasciocutáneos vulvoperineales de Málaga en una paciente pediátrica afecta de este síndrom [...] e, describiendo los pasos del procedimiento y las bases anatómicas en las que se fundamenta. Esta técnica permite la creación de una neovagina sensible, con una cobertura de excelente calidad, con un ángulo de inclinación fisiológico y natural y un axis anatómico correcto para la relación sexual; se realiza en un solo tiempo quirúrgico y con mínima morbilidad para la paciente. Su principal inconveniente es el crecimiento de pelo dentro de la vagina, aunque se atenúa con el tiempo debido a un fenómeno de atrofia folicular y metaplasia cutánea. Abstract in english The incidence of vaginal agenesis is 1/4000-10000 female alive newborns. The most frequent cause is Mayer-Rokitansky-Küster-Hauser syndrome. A technique for vaginal reconstruction using the vulvoperineal fasciocutaneous flaps (Malaga flaps) in a pediatric patient affected of this syndrome is present [...] ed, describing the steps of the procedure and its anatomic basis. This technique allows the reconstruction of an excellent quality and sensible neovagina, with a physiologic inclination angle which allows the sexual intercourse, in one single stage operation and with minimal morbidity. The main inconvenient of this procedure is the hair growth inside the vagina, although it diminishes with the passage of time due to follicular atrophy and cutaneous metaplasy.

  8. In vivo dosimetry using electron paramagnetic resonance in L-alanine in gynecological low dose rate brachytherapy

    International Nuclear Information System (INIS)

    To present the results of in vivo dosimetry performed on 15 patients treated for gynecological cancer with the aim of optimizing the detector design and its application in body cavities and comparing the doses measured in vivo with those calculated by the Plato (Nucletron) system of brachytherapy treatment planning. Electron paramagnetic resonance (EPR) is, as a dosimetric method, based on the detection of free radicals generated by ionizing radiation in L-alanine. The concentration of free radicals is proportional to the absorbed dose and is determined by the EPR technique. The detectors appear as small cellulose capsules (outer diameter 5 mm, length 15 mm), tightly filled with crystalline L-alanine powder. The doses from 137Cs brachytherapy sources were measured in selected points inside the rectum and vagina. The relative deviations of measured doses from those calculated by the treatment planning system ranged from -28% to +40%. The mean deviations from the prescribed doses were relatively low (+1% for detectors placed in the rectum, - 10% for detectors placed in the vagina). However, due to a low number of samples and large standard deviations of the mean values (±23% and ±11% for detectors placed in the rectum and the vagina, respectively), the deviations of the mean values are of low statistical significance. The accuracy of the measurements was analyzed and is hereby discussed. The main sources of the differences between the measured and calculated dose should, generally, be attributed to uncertainties in the determination of the detector position inside the body as ascertained from the radiographs and to uncontrollable motion of detectors during treatment. (author)

  9. Reproducibility and genital sparing with a vaginal dilator used for female anal cancer patients

    International Nuclear Information System (INIS)

    Purpose: Acute vulvitis, acute urethritis, and permanent sexual dysfunction are common among patients treated with chemoradiation for squamous cell carcinoma of the anal canal. Avoidance of the genitalia may reduce sexual dysfunction. A vaginal dilator may help delineate and displace the vulva and lower vagina away from the primary tumor. The goal of this study was to evaluate the positional reproducibility and vaginal sparing with the use of a vaginal dilator. Materials and methods: Ten female patients treated with IMRT for anal cancer were included in this study. A silicone vaginal dilator measuring 29 mm in diameter and 114 mm in length was inserted into the vagina before simulation and each treatment. The reproducibility of dilator placement was investigated with antero-posterior and lateral images acquired daily. Weekly cone beam CT (CBCT) imaging was used to confirm coverage of the GTV, which was typically posterior and inferior to the dilator apex. Finally, a planning study was performed to compare the vaginal doses for these 10 patients to a comparable group of 10 female patients who were treated for anal cancer with IMRT without vaginal dilators. Results: The absolute values of the location of the dilator apex were 7.0 ± 7.8 mm in the supero-inferior direction, 7.5 ± 5.5 mm in the antero-posterior, and 3.8 ± 3.1 mm in the lateral direction. Coverage of the GTV and CTV was confirmed from CBCT images. The mean dose to the vagina was lower by 5.5 Gy, on average, for the vaginal dilator patients, compared to patients treated without vaginal dilators. Conclusion: The vaginal dilator tended to be inserted more inferiorly during treatment than during simulation. For these ten patients, this did not compromise tumor coverage. Combined with IMRT treatment planning, use of a vaginal dilator could allow for maximum sparing of female genitalia for patients undergoing radiation therapy for anal cancer.

  10. Actualización sobre vaginosis bacteriana / Update on bacterial vaginosis

    Scientific Electronic Library Online (English)

    Wilmer, Martínez Martínez.

    2013-12-01

    Full Text Available La vaginosis bacteriana es una enfermedad polibacteriana que afecta a muchas mujeres en todo el mundo. La mayor prevalencia se observa en países subdesarrollados y en poblaciones con factores de riesgo como la promiscuidad. La enfermedad se produce cuando los lactobacilos, presentes en la microbiota [...] normal de la vagina de mujeres sanas son reemplazados o superados en número por bacterias Gram negativas o Gram variables, anaerobias estrictas o facultativas presentes en pequeñas cantidades en la vagina sana y en el tracto gastrointestinal. La enfermedad puede cursar de forma asintomática o con leucorrea y ardor vulvar, en algunas pacientes puede ocasionar complicaciones obstétricas y ginecológicas importantes. El diagnóstico de la vaginosis bacteriana ha sido un tema controversial. Aunque existen algunos métodos diagnósticos clínicos y microbiológicos, todavía no se cuenta con un método potente para el diagnóstico eficaz de la vaginosis bacteriana. Abstract in english Bacterial vaginosis is a polybacterial disease affecting many women all over the world. The highest prevalence occurs in underdeveloped countries and in population with risky factors such as promiscuity. The disease takes place when lactobacilli from vaginal microbiota are replaced or outweighed in [...] number by Gram negative or Gram variable, strict or facultative anaerobes bacteria that can be found in the gastrointestinal tract and in few concentrations in healthy vagina. The disease may be asymptomatic or presents with leucorrhea and vulvar burning, and in some patients it can cause major obstetric and gynecological complications. The diagnosis of bacterial vaginosis has been a controversial issue. Although some clinical and microbiological diagnostic methods exist, a powerful method for the effective diagnosis of bacterial vaginosis does not exist yet.

  11. Morfologia macroscópica do aparelho reprodutor feminino de Leontopithecus cativos (Lesson, 1840 Primates-Callitrichidae Gross morphology of the female genital tract of captive Leontopithecus (Lesson, 1840 Primates-Callitrichidae

    Directory of Open Access Journals (Sweden)

    L. Pissinatti

    2008-12-01

    Full Text Available Descreveu-se o sistema reprodutor feminino em três espécies de mico-leão Leontopithecus (Lesson 1840, cativos: L. rosalia, L. chrysopygus e L. chrysomelas. A vulva está delimitada pelos lábios vulvares menores e com clitóris conspícuo. A superfície do períneo urogenital apresenta elevações papilares mais concentradas nos lábios vulvares, conferindo-lhe aspecto rugoso. O vestíbulo vaginal constitui um tubo muscular de parede espessa que se estende da rima da vulva até o óstio da vagina. A vagina é um tubo muscular alongado e achatado dorsoventralmente, que comunica o vestíbulo vaginal ao colo uterino. O útero piriforme está localizado na porção caudal da cavidade abdominal. Craniolateralmente abrem-se tubas uterinas convolutas e ovários grosseiramente fusiformes de superfície lisa.It is described the female genital tract of three species of lion tamarin: Leontopithecus rosalia, L. chrysopygus, and L. chrysomelas. Fifteen animals were selected from the Museum of the Center of Primatology of Rio de Janeiro - CPRJ/FEEMA. The vulva is delimited by the labia and has a conspicuous clitoris. The surface of the urogenital perineum has papillary elevations more concentrated in the labia, which results in a rough aspect. The vestibule is a thick-walled muscular tube, extending from the pudendal cleft to the vaginal orifice. The vagina is an elongated and flat muscular tube, which communicates dorsoventrally the vestibulum and the cervix of uterus. The pyriform uterus is located in the caudal portion of the abdominal cavity. Craniolaterally, the convolute uterine tubes open, enveloping the ovaries, which are roughly fusiform with a smooth surface.

  12. Comparison of Group B Streptococcal Colonization in the Pregnant Diabetic and Non-Diabetic Women

    Directory of Open Access Journals (Sweden)

    Akhlaghi Farideh

    2009-05-01

    Full Text Available - To Compare colonization of group B streptococcus (GBS in diabetic and non-diabetic pregnant women. In this prospective study 50 pregnant women with diabetes mellitus (both pregestational and gestational and 43 pregnant women without diabetes between 33 and 37 weeks' gestation were evaluated. Three samples for Group B streptococcal culture detection were obtained from each subject in the following order: perinea sample, vaginal sample, and an anorectic sample. All had singleton gestations, negative tests for human immunodeficiency virus, and intact membranes at enrollment. Pearson chi-square and fisher, Exact test were used when appropriate. Most common site of GBS colonization in all women was vagina (11.8%. Colonization of group B streptococcus in control group included vagina (7% perineum (0.3% and rectum 0.3% and in diabetic group included vagina (16% perineum (16% and rectum (16%. Although comparison was shown higher vaginal colonization rate in diabetic group (16% versus 7% but difference was not significant (P=0.154.The prevalence of group B streptococcus colonization in gestational diabetes was 20% and higher than pregestational diabetic women. Among women with pregestational diabetes, the prevalence of group B streptococcus colonization was 15% in non-insulin dependent diabetic women and 10% in insulin dependent diabetic women (P> 0.05. Comparison between two groups showed high rectal colonization in diabetic group and difference was significant (P= 0.027. Pregnant diabetic patients have higher carriage rates of group B streptococcus (GBS in rectum than non-diabetic pregnant women and diabetes is a risk factor for group B streptococcus colonization during pregnancy.

  13. The usefulness of magnetic resonance imaging (MRI) in cervical carcinoma assessment - a preliminary report

    International Nuclear Information System (INIS)

    The aim of diagnostic imaging is not so much the detection of cervical carcinoma, but the evaluation of its stage. In view of this the aim of this study included: 1) comparison of MR results with the results of histological examinations after operations with reference to the dimensions of cervical carcinoma; 2) assessment of the sensitivity and specificity of MRl in the evaluation of parametrium infiltration; 3) analysis of the sensitivity and specificity of MRI in the evaluation of infiltration of the vagina and uterus; 4) assessment of the usefulness of this method in the detection of metastases to lymph nodes.The material consisted of pelvic MRI, obtained with 2T Elscint unit in 15 patients with cervical carcinoma, aged 37 to 73 years. All patients underwent surgical treatment within 30 days after MR. During the MR examination the following sequences were performed: SE (spin echo) T1 (longitudinal relaxation time) in axial projection before administration of gadolinium (Gd-DTPA); SE T1 in axial, frontal and sagittal projections after contrast injection and FSE (fast spin echo) T2 (transversal relaxation time) in axial, frontal and sagittal projections.1) in the assessment of cervical carcinoma dimensions MRI results are highly concordant with the results of postoperative histological examination (p = 0. 9389); 2) in the assessment of parametrium infiltration sensitivity and specificity of MRI are 75% and 100%, respectively; 3) in the assessment of the infiltration of the vagina and uterine corpus the sensitivity and specificity of MRI imaging were respectively 100% and 85%; 100% and 100%; 4) in the detection of lymph node metastases MRI sensitivity was 67% and its specificity 100%. In patients with cervical carcinoma MRI is a valuable method for the assessment of tumour dimensions, parametrium infiltration, infiltration of the vagina and uterine corpus.(author)

  14. Morfologia macroscópica do aparelho reprodutor feminino de Leontopithecus cativos (Lesson, 1840) Primates-Callitrichidae / Gross morphology of the female genital tract of captive Leontopithecus (Lesson, 1840) Primates-Callitrichidae

    Scientific Electronic Library Online (English)

    L., Pissinatti; R., Tortelly; M., Porto; C.H.F., Burity; A., Pissinatti.

    2008-12-01

    Full Text Available Descreveu-se o sistema reprodutor feminino em três espécies de mico-leão Leontopithecus (Lesson 1840), cativos: L. rosalia, L. chrysopygus e L. chrysomelas. A vulva está delimitada pelos lábios vulvares menores e com clitóris conspícuo. A superfície do períneo urogenital apresenta elevações papilare [...] s mais concentradas nos lábios vulvares, conferindo-lhe aspecto rugoso. O vestíbulo vaginal constitui um tubo muscular de parede espessa que se estende da rima da vulva até o óstio da vagina. A vagina é um tubo muscular alongado e achatado dorsoventralmente, que comunica o vestíbulo vaginal ao colo uterino. O útero piriforme está localizado na porção caudal da cavidade abdominal. Craniolateralmente abrem-se tubas uterinas convolutas e ovários grosseiramente fusiformes de superfície lisa. Abstract in english It is described the female genital tract of three species of lion tamarin: Leontopithecus rosalia, L. chrysopygus, and L. chrysomelas. Fifteen animals were selected from the Museum of the Center of Primatology of Rio de Janeiro - CPRJ/FEEMA. The vulva is delimited by the labia and has a conspicuous [...] clitoris. The surface of the urogenital perineum has papillary elevations more concentrated in the labia, which results in a rough aspect. The vestibule is a thick-walled muscular tube, extending from the pudendal cleft to the vaginal orifice. The vagina is an elongated and flat muscular tube, which communicates dorsoventrally the vestibulum and the cervix of uterus. The pyriform uterus is located in the caudal portion of the abdominal cavity. Craniolaterally, the convolute uterine tubes open, enveloping the ovaries, which are roughly fusiform with a smooth surface.

  15. Spontaneous rupture of urinary bladder associated with massive fecal impaction (fecaloma).

    Science.gov (United States)

    Chute, Dennis J; Cox, John; Archer, Michael E; Bready, Robert J; Reiber, Kari

    2009-09-01

    We report a case of sudden death due to a catastrophic spontaneous rupture of a urinary bladder associated with megacolon due to a fecal impaction (fecaloma). The massively distended rectum and sigmoid colon filled the pelvic cavity and pressed up against the posterior aspects of the uterus, vagina, and urinary bladder. This produced bladder outlet obstruction, followed by massive dilatation and rupture of the urinary bladder, bilateral hydronephrosis, and a 3.5 liter collection of urinary fluid within the abdominal cavity. Complications of chronic constipation, fecalomas, and rupture of the urinary bladder are reviewed. PMID:19696587

  16. Human Papillomavirus Community in Healthy Persons, Defined by Metagenomics Analysis of Human Microbiome Project Shotgun Sequencing Data Sets

    OpenAIRE

    Ma, Yingfei; Madupu, Ramana; Karaoz, Ulas; Nossa, Carlos W.; Yang, Liying; Yooseph, Shibu; Yachimski, Patrick S; Brodie, Eoin L.; Nelson, Karen E; Pei, Zhiheng

    2014-01-01

    Human papillomavirus (HPV) causes a number of neoplastic diseases in humans. Here, we show a complex normal HPV community in a cohort of 103 healthy human subjects, by metagenomics analysis of the shotgun sequencing data generated from the NIH Human Microbiome Project. The overall HPV prevalence was 68.9% and was highest in the skin (61.3%), followed by the vagina (41.5%), mouth (30%), and gut (17.3%). Of the 109 HPV types as well as additional unclassified types detected, most were undetecta...

  17. Comprehensive Control of Human Papillomavirus Infections and Related Diseases

    OpenAIRE

    Bosch, F Xavier; Broker, Thomas R.; Forman, David; Moscicki, Anna-Barbara; Maura L. Gillison; Doorbar, John; Stern, Peter L.; Stanley, Margaret; Arbyn, Marc; Poljak, Mario; Cuzick, Jack; Castle, Philip E.; Schiller, John T.; Lauri E. Markowitz; Fisher, William A.

    2013-01-01

    Infection with human papillomavirus (HPV) is recognized as one of the major causes of infection-related cancer worldwide, as well as the causal factor in other diseases. Strong evidence for a causal etiology with HPV has been stated by the International Agency for Research on Cancer for cancers of the cervix uteri, penis, vulva, vagina, anus and oropharynx (including base of the tongue and tonsils). Of the estimated 12.7 million new cancers occurring in 2008 worldwide, 4.8% were attributable ...

  18. Epidemiology of Human Papillomavirus Infection in Men, in Cancers other than Cervical and in Benign Conditions

    OpenAIRE

    Giuliano, Anna R.; Tortolero-Luna, Guillermo; Ferrer, Elena; Burchell, Ann N.; de Sanjose, Silvia; Kjaer, Susanne Kruger; Muñoz, Nubia; Schiffman, Mark; Bosch, F Xavier

    2008-01-01

    Human Papillomavirus (HPV) infection is commonly found in the genital tract of men and women with or without any clinical lesion. The association of HPV DNA with several different ano-genital cancers other than cervical has been reported for the vulva, vagina, anus and penis. HPV DNA has also been identified in head and neck cancers in the oral cavity, the oropharynx and the larynx in both sexes. In men, 80–85% of anal cancers and close to 50% of penile cancers are associated with HPV infecti...

  19. The long-term management and outcomes of cloacal anomalies

    OpenAIRE

    Fernando, M. Ashani; Creighton, Sarah M.; Wood, Dan

    2014-01-01

    Cloacal anomalies occur when failure of the urogenital septum to separate the cloacal membrane results in the urethra, vagina, rectum and anus opening into a single common channel. The reported incidence is 1:50,000 live births. Short-term paediatric outcomes of surgery are well reported and survival into adulthood is now usual, but long-term outcome data are less comprehensive. Chronic renal failure is reported to occur in 50 % of patients with cloacal anomalies, and 26–72 % (dependant on th...

  20. Effect of extenders, postdilution intervals, and seasons on semen quality in dairy goats

    OpenAIRE

    QURESHI, Muhammad Subhan; Khan, Daulat; MUSHTAQ, Anila; AFRIDI, Shoaib Sultan

    2013-01-01

    The breeding of female dairy goats with good quality sires has been a problem in rural areas and artificial insemination (AI) provides an answer to this issue. To develop an AI model, a total of 9 bucks were purchased from a local market. Semen was collected in an artificial vagina, the libido was noted, and the semen was evaluated for its physical characteristics. The libido, semen volume, mass motility, individual motility, and sperm concentration were 2.94 ± 0.25 (scale of 1-3), 0.79 ± 0.5...