WorldWideScience

Sample records for Vagina

  1. Vagina

    Science.gov (United States)

    The vagina is the female body part that connects the womb (uterus) and cervix to the outside of the ... The vagina is a muscular tube lined with mucus membranes. Its opening is between the urethra (where urine exits ...

  2. Irradiated vagina

    International Nuclear Information System (INIS)

    The gross and microscopic changes following different modes of therapy for 97 cases of Stage I and II carcinoma of the cervix were studied. Features frequently present in the radiotherapy patients were: narrowing or obliteration of the vagina, pelvic fibrosis, pain or discomfort on pelvic examination, and gross and microscopic changes in the vagina typical of radiation fibrosis; in addition, the vaginal cytology was not altered after estrogen stimulation. These features were less frequent in the surgical patients. Of all the organs in the body, the vagina is exposed to the heaviest doses of irradiation. (U.S.)

  3. Air in vagina

    International Nuclear Information System (INIS)

    Computed tomography of the normal female pelvis may show the presence of a tiny air bubble within the vagina. Among 2800 female abdomino-pelvic CTs, 27 were found to contain large amounts of intravaginal air. Twenty-three patients suffered from pelvic malignancy while in 4, non-tumorous pelvic pathology was present. Detection of air bubbles in the vagina is abnormal and indicates, in the majority of cases, an intrapelvic malignancy. (orig.)

  4. Malignant melanoma of the vagina.

    OpenAIRE

    Ara, Rahat; Ohnmar, Saw

    2011-01-01

    Carcinoma of the vagina is uncommon and only constitutes two percent of malignant neoplasms of the female genital tract. Malignant melanoma of the vagina is rarer and accounts for only 3.2% of all vaginal cancers. It presumably arises from melanocytes found in the vagina of three percent of normal women. It is a very aggressive tumour and the overall prognosis is poor despite the treatment. We report the case of an 81-year-old woman who presented with per vagina bleeding secondary to a malign...

  5. Vagina evaluation by MR imaging

    International Nuclear Information System (INIS)

    The author evaluated MR imaging of the vagina under different hormonal stimuli (25 patients) and assessed the role of MR imaging in the evaluation of congenital abnormalities (15 patients), primary (3) and metastatic (5) neoplasms, and reconstructive surgery (3). The findings were confirmed surgically. The appearance of the mucosa and vaginal wall was influenced by hormonal status. The presence of the vagina (45 patients), absence of the vagina (4), and the presence of duplication anomaly (3) were always accurately demonstrated on MR images. Carcinoma and metastases were depicted as tumor interrupting the low intensity signal of the muscular wall of the vagina. In two of three patients who underwent reconstructive surgery, postsurgical perivaginal abscesses developed that were correctly displayed on MR images. The normal and abnormal vaginas were exquisitely shown on MR images. For complicated congenital abnormalities, complications of postreconstructive surgery, and staging of neoplasms, MR imaging should be considered a primary imaging modality

  6. Brenner tumour of the vagina.

    OpenAIRE

    Rashid, A. M.; Fox, H.

    1995-01-01

    Polyps of the vagina are rare and are either of inflammatory/reactive or neoplastic origin. A case of extraovarian Brenner tumour of the vagina in a postmenopausal woman, who presented with a vaginal polyp, is described. The polyp was excised and on histological examination, had the triphasic pattern (transitional, glandular and stromal) characteristic of Brenner tumour. The histogenesis of Brenner tumour is discussed in the context of this unusual location and the controversy of its origin.

  7. Antibiotic susceptibility of Atopobium vaginae

    Directory of Open Access Journals (Sweden)

    Verschraegen Gerda

    2006-03-01

    Full Text Available Abstract Background Previous studies have indicated that a recently described anaerobic bacterium, Atopobium vaginae is associated with bacterial vaginosis (BV. Thus far the four isolates of this fastidious micro-organism were found to be highly resistant to metronidazole and susceptible for clindamycin, two antibiotics preferred for the treatment of BV. Methods Nine strains of Atopobium vaginae, four strains of Gardnerella vaginalis, two strains of Lactobacillus iners and one strain each of Bifidobacterium breve, B. longum, L. crispatus, L. gasseri and L. jensenii were tested against 15 antimicrobial agents using the Etest. Results All nine strains of A. vaginae were highly resistant to nalidixic acid and colistin while being inhibited by low concentrations of clindamycin (range: G. vaginalis strains were also susceptible for clindamycin ( 256 ?g/ml but susceptible to clindamycin (0.023 – 0.125 ?g/ml. Conclusion Clindamycin has higher activity against G. vaginalis and A. vaginae than metronidazole, but not all A. vaginae isolates are metronidazole resistant, as seemed to be a straightforward conclusion from previous studies on a more limited number of strains.

  8. Intestinal prolapse through the vagina.

    OpenAIRE

    Patankar, R. V.; Scott, S. D.; Mcginn, F. P.

    1993-01-01

    We describe the case of a 68-year-old woman who presented with an acute onset spontaneous vaginal vault rupture and intestinal prolapse through the vagina. Results of a literature survey are presented and the causes of vaginal vault rupture are discussed.

  9. Vesicouterine fistula and blind vagina

    International Nuclear Information System (INIS)

    A case of vesicouterine fistula with blind vagina following cesarean section for obstructed labor is presented. It was surgically treated by fistulectomy, cervicoplasty and maintenance of bladder and cervical potency by catheterization. Intrauterine synechiae formation was prevented by copper T insertion and oral contraceptive pills. The patient is making uneventful a symptomatic progress planning to conceive. (author)

  10. Yolk sac tumor of the vagina.

    OpenAIRE

    Parvin Mahzouni; Shervin Pejhan; Mahmoud Ashrafi

    2007-01-01

    ABSTRACT Malignant germ-cell tumors GCT are rare tumors of childhood accounting for less than 3% of pediatric malignancies. Endodermal sinus tumors EST form the most common histologic subtype of malignant GCT. The vagina is an extremely rare site for GCTs. An 8-month-old female was admitted with a short history of vaginal bleeding, and a mass protruding from the vagina. A mass was palpable anteriorly on rectal examination. Computed tomography showed a tumor mass posterior to the bladder. A...

  11. Reconstruction of Congenital Defects of the Vagina

    OpenAIRE

    Eldor, Liron; Friedman, Jeffrey D.

    2011-01-01

    Congenital absence of the vagina is a relatively rare condition most commonly associated with Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome. Historically, several reconstructive techniques have been described to provide for functional vaginal reconstruction on these patients, both operative and nonoperative. Although there are many advantages and disadvantages of the various procedures, one experience with the use of split thickness skin grafts to reconstruct the vagina has produced acceptab...

  12. Endodermal Sinus Tumor of Vagina in Infants

    OpenAIRE

    Brijesh Thakur; Vatsala Misra; Pallavi Singh; Jitendra Singh Nigam; Smita Chauhan

    2013-01-01

    Endodermal sinus tumor (or Yolk Sac tumor) of the vagina is a rare malignant germ-cell tumor which is seen exclusively in children younger than 3 years of age. We report two cases of endodermal sinus tumor of the vagina. In both cases no radiological investigation was done and serum alpha-fetoprotein was elevated. The histopathological examination of both the tumor masses revealed vaginal endodermal sinus tumor. Periodic-acid-Schiff stain with diastase showed diastase resistant hyaline globul...

  13. Embryonal rhabdomyosarcoma of the vagina in children

    International Nuclear Information System (INIS)

    Eight cases of childhood rhabdomyosarcoma arising in the vagina are presented. All were treated with curie therapy, and 7 of 8 received chemotherapy in addition. With a median follow up of 4 yr, 6 of 7 had local control without surgery, 1 required colpohysterectomy for microscopic disease after curie therapy. These techniques of curie therapy and chemotherapy for localized rhabdomyosarcoma of the vagina allow one to obtain the cure while avoiding mutilating surgery. (author)

  14. Brachytherapy for the malignant tumours of vagina

    International Nuclear Information System (INIS)

    In 1986-1995 a total of 134 patients with malignant tumours of vagina were treated by interstitional radiotherapy. Fifty-two patients were irradiated with 60Co sources, and 82 patients - with 252Cf sources. Fourteen patients had primary carcinoma of vagina, 120 patients had metastases and recurrences in vagina. We used 60Co and 252Cf irradiation sources; their active length was 20-30 mm with an increasing activity at the ends. Special template devices made it possible to implant 2-16 sources in a strictly pre-set geometry. Radiation treatment was mainly interstitial therapy. Some patients underwent additional external radiotherapy (20-40 Gy), taking into account the time and dosage of previously applied therapy. Complete tumour regression was observed in 13 (92.8%) patients with primary vaginal carcinomas. In 1 patient more than 50% partial regression was observed. In 114 (85%) patients with tumour recurrences and metastases to the vagina complete tumour regression was observed. Partial regression was observed in 14 (10.4%), and there was no effect in 6 (4.4%) patients with tumour recurrences and metastases to the vagina. Five year survival was 46% for all treated patients. Mild radiation reactions were found in 35 (26.1%) patients. In 3 patients radiation ulcers developed in irradiation area. It should be noted that radiation reactions appeared later when radiation sources with 252Cf were used>252Cf were used

  15. Imaging of the vagina and vulva

    International Nuclear Information System (INIS)

    In gynecological daily practices, the vulva and vagina are examined during physical examination, however there are situations where this is not possible or it is needed to determine the extension of an injury through imaging methods. The magnetic resonance imaging is an excellent cross-sectional modality for evaluation the alterations of vulva and vagina due its multiplanar evaluation and high tecidual contrast. Other cross-sectional modalities are ultrasound and enhanced computed tomography. This paper intends to give an overview of vaginal and vulvar pathology that can be identified by the radiologist. (author)

  16. Yolk sac tumor of the vagina

    International Nuclear Information System (INIS)

    Malignant germ-cell tumors (GCT) are rare tumors of childhood accounting for less than 3% of pediatric malignancies. Endodermal sinus tumors (EST) form the most common histologic subtype of malignant GCT. The vagina is an extremely rare site for GCTs. An 8-month-old-female was admitted with a short history of vaginal bleeding, and a mass protruding from the vagina. A mass was palpable anteriorly on rectal examination. Computed tomography showed a tumor mass posterior to the bladder. A biopsy revealed a vaginal EST. The serum alpha-fetoprotein was elevated. Vaginohysterectomy was carried out. She was subsequently referred to the oncologist for further management. (author)

  17. Infektionen an Vulva, Vagina und Zervix

    OpenAIRE

    Buchberger, Andrea

    2009-01-01

    Selektive Literaturarbeit und Internetkompendium zu Infektionen an Vulva, Vagina und Zervix. 654 Fachartikel der vergangenen Dekade werden zitiert, 90 Abbildungen und Tabellen strukturieren die Flut an Daten. Es wird eine gute Übersicht über genitale Infektionen gegeben. Die wissenschaftlich fundierten Aussagen aus dem Grundlagenteil werden im Internetkompendium komprimiert auf einer Startseite zusammengefügt, in den tieferen Ebenen sind weiterführende Kommentare verlinkt. In einem diagno...

  18. Primary leiomyosarcoma of vagina: case report

    International Nuclear Information System (INIS)

    Primary malignant lesions of the vagina are uncommon and represent about 1% of all gynecological malignancies. Most of these neoplasms are carcinomas. Sarcomas comprise less than 2% of all malignant vaginal tumours. In this present article, we describe a primary vaginal leiomyosarcoma in a 40-years-old woman. (author)

  19. Endometrial stromal sarcoma arising in vaginaEndometrial stromal sarcoma arising in vagina

    OpenAIRE

    Liu, Zhaoxia; Ding, Jiao; Li, Xia; Yu, Kehan

    2013-01-01

    Endometrial stromal sarcoma (ESS) arising in the vagina is an extremely rare extrauterine endometrial stroma sarcoma, with only 4 cases reported in the literature up to date. Here we report a case of neoplasm originating from vagina. A 32-year-old woman complained of intermittent vaginal bleeding especially after intercourse. A mass with a diameter of 1.0 cm was found in the middle and upper segments of the right posterior vaginal wall. Biopsy showed ESS. Total abdominal hysterectomy, unilate...

  20. Cáncer primario de vagina / Vaginal primary cancer

    Scientific Electronic Library Online (English)

    Raiza, Ruiz Lorente; Daisy, Hernández Durán; Tania Graciela, Tamayo Lien; Ana Isabel, de la Torre.

    2010-09-01

    Full Text Available El carcinoma primario de vagina es una neoplasia poco frecuente, representando solamente el 1-2 % de todos los tumores malignos del área ginecológica. Según la FIGO solo se considera como cáncer primario de vagina a aquellas lesiones confinadas a la vagina sin invasión del cuello uterino o la vulva. [...] El pronóstico depende principalmente del estadio en que se encuentra la enfermedad, pero la supervivencia se reduce en pacientes mayores de 60 años de edad, si son sintomáticos al momento del diagnóstico, tienen lesiones del centro y tercio inferior de la vagina o tienen tumores mal diferenciados. Los objetivos de este estudio fueron evaluar la experiencia en el manejo del cáncer primario de vagina, identificar variables demográficas y clínicas, mostrar la variedad histológica de presentación de esta neoplasia tan rara, así como el grado de diferenciación en cada caso. Igualmente relacionar estadio del cáncer, tratamiento y respuesta en cada una de las pacientes. Se trata de un estudio retrospectivo de cinco pacientes con cáncer primario de vagina atendidas en el Servicio de Patología de cuello del Hospital Ramón González Coro, durante el año 2008. La evaluación inicial consistió en una historia clínica completa, examen físico haciendo hincapié en el área ginecológica descartando lesiones en vulva o cuello uterino. A todas las pacientes se les realizó biopsia excisional del tumor, enviando la muestra al estudio histopatológico. Se les realizó cistoscopia, rectoscopia, urograma descendente, a aquellas pacientes con sospecha de infiltración de vejiga o recto, laboratorio, radiografía del tórax y se estadiaron según la clasificación de la FIGO. Abstract in english The primary vaginal carcinoma is a uncommon neoplasm present only in the 1-2% of all the malignant tumors of gynecology area. According to International Federation of Gynecology and Obstetrics only is considered as a primary vaginal cancer of those lesions confined to vagina without invasion of cerv [...] ix or the vulva. The prognosis depends mainly on the disease stage, but the survival is reduced in patients aged over 60 if they are symptomatic at diagnosis, have lesions of the center and the inferior third of vagina or have ill-differentiated. The objectives of present study were to assess the experience in the vaginal primary cancer management, to identify demographic and clinical variables, to show the histological variety of presentation of this so rare neoplasm, as well as the differentiation grade of each case and to relate the cancer stage, the treatment and the response of each patient. It is retrospective study conducted in 5 patients presenting vaginal primary cancer seen in the Cervix Pathology Service of the "Ramón González Coro" Gynecology and Obstetrics Hospital during 2008. The initial assessment included a complete medical record, physical examination with emphasis in the gynecological area ruling out vulva or cervix uteri lesions. All patients underwent excision biopsy of tumor with the corresponding histopathological study of the sample. A cystoscopy, rectoscopy descending urogram were carried out in those patients with a possible bladder or rectum infiltration, lab tests, thorax Rx staged according the International Federation of Gynecology and Obstetrics classification.

  1. Radiation treatment policy for carcinoma vagina

    International Nuclear Information System (INIS)

    A small group of patients of primary carcinoma vagina is presented with their clinical profile and with an emphasis on external radiation therapy for such cases. Short-term control rate has been encouraging. It is recommended that an aggressive treatment policy even in locally advanced tumour and radical radiation with suitable branchytherapy practices can give as good results as with surgery with minimum of morbidity. Relevant literature has been reviewed. (auth.)

  2. Lymphoepithelioma–like carcinoma of the vagina

    OpenAIRE

    Mccluggage, W.

    2001-01-01

    This report describes a lymphoepithelioma-like carcinoma of the vagina. Although such tumours are well described in the cervix this is only the second report of such a neoplasm at this site. Histology showed a well circumscribed lesion composed of syncytial sheets of epithelioid tumour cells with an intense inflammatory infiltrate, largely consisting of T lymphoid cells. In situ hybridisation and immunohistochemistry for Epstein-Barr virus were negative. A review of the literature reveals tha...

  3. Linfoma no Hodgkin primario de vagina

    Scientific Electronic Library Online (English)

    Eva María, Guldrís N; María Pía, Vázquez C; Elba, Carballo N; Magdalena, Porto Q; Luis, Heliodoro Alba O; Begoña, Iglesias R.

    Full Text Available La afectación primaria del tracto genital femenino de los linfomas no Hodgkin es poco frecuente (2% de los linfomas primarios extraganglionares). Los órganos más afectados son los ovarios seguidos del cérvix, siendo la localización endometrial y vaginal extremadamente rara. Presentamos el caso de un [...] a paciente de 44 años diagnosticada de linfoma primario de vagina, estadio IE A, con remisión completa tras tratamiento combinado quimioterápico y quirúrgico. Es importante tener presente estas raras aunque posibles localizaciones de linfomas para evitar que se puedan confundir con lesiones inflamatorias u otros tipos de tumores que nos lleven a un fracaso terapéutico. Abstract in english Primary non-Hodgkin lymphomas rarely involve the female genital tract (2% of primary extranodal lym-phomas). The ovaries followed by the cervix are the most common affected sites while the involvement of the endometrium and vagina is extremely rare. We report the case of a 44 year old woman with a p [...] rimary lymphoma of the vagina, stage IE A, with complete remission after combined chemotherapy and surgical treatment. These rare but possible locations must be kept in mind to avoid misdiagnosis with inflammatory lesions or other types of tumors which may lead us to a therapeutic failure.

  4. Primary leiomyosarcoma of vagina: case report; Leiomiossarcoma primario de vagina: relato de caso

    Energy Technology Data Exchange (ETDEWEB)

    Vieira, Leonardo Jose [Hospital ASCONCER Associacao Feminina de Prevencao e Combate ao Cancer, Juiz de Fora, MG (Brazil). Servico de Cirurgia; Freitas, Rosyane Rena de [Juiz de Fora Univ., MG (Brazil). Faculdade de Medicina; Oliveira, Alexandre Ferreira de [Juiz de Fora Univ., MG (Brazil). Faculdade de Medicina. Disciplina de Cirurgia Gastroenterologica; Assis, Raimunda Violante Campos de [Juiz de Fora Univ., MG (Brazil). Faculdade de Medicina. Dept. de Patologia; Cugola, Elaine Aline; Costa, Sandra Marcia Carvalho Ribeiro

    2004-07-01

    Primary malignant lesions of the vagina are uncommon and represent about 1% of all gynecological malignancies. Most of these neoplasms are carcinomas. Sarcomas comprise less than 2% of all malignant vaginal tumours. In this present article, we describe a primary vaginal leiomyosarcoma in a 40-years-old woman. (author)

  5. Small cell carcinoma of the vagina

    International Nuclear Information System (INIS)

    A case of localized small cell neuroendocrine carcinoma of the vagina is reported. The patient was treated with concurrent chemoradiation with significant toxicity but obtained a complete response. Thirteen months after therapy the patient developed distant metastasis and died shortly thereafter. Review of the literature found that patients treated with local therapy alone had a shorter survival and died of systemic disease. As with small cell neuroendocrine carcinomas arising from other sites, systemic relapse remains an important issue that warrants combination therapies, although in pelvic sites this may be associated with an increase in side-effects. Copyright (2000) Blackwell Science Pty Ltd

  6. Radiotherapy of malignant tumors of the vagina

    International Nuclear Information System (INIS)

    A new method of combined radiotherapy for cancer of the vagina is presented: it includes contact (intracavitary and interstitial) gamma-therapy based on the principle of the manual and automated administration (using the AGAT-B unit) of endostats and low and high activity radiation sources, and gamma irradiation with irregular shaped fields. The problems of fractionation, a choice of required irradiation volumes as well as summary absorbed dose levels are discussed. An analysis of the clinical efficacy was based delayed results. The 5-year survival rate in the general group of patients was 41.2%

  7. Primary Small Cell Carcinoma of the Vagina

    OpenAIRE

    Rosekeila Simões Nomelini; Amp Xf Coli, Mayra Coelho B.; Eddie Fernando Candido Murta; Carlos Saldanha, Jo Amp Xe O.; Rafael Oliveira

    2013-01-01

    The primary small cell carcinoma of the vagina is rare, and it is a highly aggressive malignancy with no consensus regarding the treatment of this tumor. The survival rate for patients treated in the early stages is around two years. We related the case report of a patient of 41 years with a vegetative and necrotic lesion in left vaginal wall, in middle and upper third, and involvement of parametrium in its proximal third and medium third. A biopsy showed a small cell undifferentiated carcino...

  8. Endometrial stromal sarcoma arising in vagina.

    Science.gov (United States)

    Liu, Zhaoxia; Ding, Jiao; Li, Xia; Yu, Kehan

    2013-01-01

    Endometrial stromal sarcoma (ESS) arising in the vagina is an extremely rare extrauterine endometrial stroma sarcoma, with only 4 cases reported in the literature up to date. Here we report a case of neoplasm originating from vagina. A 32-year-old woman complained of intermittent vaginal bleeding especially after intercourse. A mass with a diameter of 1.0 cm was found in the middle and upper segments of the right posterior vaginal wall. Biopsy showed ESS. Total abdominal hysterectomy, unilateral salpingo-oophorectomy (right) and partial vaginectomy were performed. No ESS lesion was found in endometrium. The patient received six courses of platinum-containing combination chemotherapy after surgery and was free of tumor 18 months after the diagnosis of ESS. The diagnosis of ESS relies on pathologic examination. CD10 is the most useful immunohistochemical marker for the diagnosis of this tumor. The mainstay treatment of ESS is surgery. Local excision and ovarian retaining may be considered in premenopausal women. PMID:24294390

  9. Malignant melanoma of the vagina: CT and MR findings

    International Nuclear Information System (INIS)

    We report CT and MR findings in two cases of primary malignant melanoma of the vagina, one arising from cervicovaginal junction mimicking squamous cell carcinoma of the cervix and the other one recurring at vagina after resection. Two cases of malignant melanoma had high-attenuation on CT and high signal intensity on T1-weighted MR images and enhanced well after gadopentetate dimeglumine administration

  10. vagina artificial, utilizando como estímulo objetos inanimados

    Directory of Open Access Journals (Sweden)

    Virginio Aguirre Flores

    2005-01-01

    Full Text Available Con el fi n de desarrollar una metodología para entrenar carneros en la recolección de semen con vagina artifi cial (VA, montando un objeto inanimado, se utilizaron nueve animales que se sometieron a cuatro etapas de preparación. La primera con el propósito de lograr la manifestación del repertorio sexual natural, y el resto para llevar a cabo un programa de condicionamiento operante: cuando la respuesta correcta (monta sucedía, en un inicio provocada por un estado de motivación sexual, se daba un refuerzo positivo o estímulo incondicionado (eyaculación, con lo que eventualmente y mediante un proceso de generalización la respuesta condicionada (primero montar a una hembra que no estaba en celo y luego a un objeto inanimado se aprendió como la respuesta correcta. Al inicio de cada fase 33%-55% de los carneros no eyacularon; sin embargo, al fi nal de las fases 1-3, todos eyacularon al menos una vez, al fi nal del entrenamiento fue imposible recolectar semen de un macho. Se concluye que mediante la metodología propuesta 90% de los machos jóvenes pueden ser entrenados para montar objetos inanimados con el fi n de recolectar semen mediante VA.

  11. Radiation therapy for carcinoma of vagina

    International Nuclear Information System (INIS)

    Thirty-four patients with carcinoma of the vagina were treated by radiotherapy at the Hyogo Medical Center for Adults between April 1965 and May 1990. All patients were treated with a combination of external and intracavitary or interstitial irradiation. Twenty-three patients had squamous cell carcinoma, five had adenocarcinoma and two had malignant melanoma. The five-year survival of patients with squamous cell carcinoma was 70% in Stage I (10 patients), 40% in Stage II (seven patients), 50% in Stage III (three patients) and 0% in Stage IV (three patients). Local control was achieved in 72.7% of the patients with squamous cell carcinoma and 60% of those with adenocarcinoma. However, neither of the malignant melanomas was controlled. Five patients had severe complications that required surgical treatment: severe proctitis and small-bowel perforation, ileus, rectal stenosis, vesicovaginal fistula and small-bowel perforation. Local and pelvic failure was noted in three patients. Patients with previous hysterectomy were more likely to develop serious treatment-related complications. (author)

  12. Aggressive angiomyxoma of the vagina: a case report / Angiomiosarcoma agressivo da vagina: relato de caso

    Scientific Electronic Library Online (English)

    Cátia, Lourenço; Nuno, Oliveira; Filomena, Ramos; Isabel, Ferreira; Mário, Oliveira.

    2013-12-01

    Full Text Available O angiomixoma agressivo é tumor raro de tecidos moles, de lento crescimento e que geralmente ocorre na pelve e nas regiões perineais de mulheres em idade reprodutiva, com forte tendência à recorrência local. Devido à sua raridade, ele é frequentemente mal diagnosticado. A exerese cirúrgica é a modal [...] idade principal para o tratamento do angiomixoma agressivo. Descrevemos aqui um caso de angiomixoma vaginal agressivo em mulher de 47 anos de idade, que foi diagnosticado apenas após exame histológico. Descrevemos também a etiologia e apresentação, bem como o diagnóstico e tratamento desse raro tumor. O angiomixoma da vulva e vagina constitui doença rara. Devido à raridade desse tumor e à ausência de elementos diagnósticos, o diagnóstico pré-operatório é difícil, mas deveria ser considerado na presença de qualquer massa na região genital, perianal e pélvica de mulheres em idade reprodutiva. Portanto, esses casos deveriam ser submetidos a propedêutica radiológica completa antes da exerese, uma vez que um pré-diagnóstico pode modificar a modalidade de tratamento e o prognóstico do paciente. Abstract in english Aggressive angiomyxoma is a rare, slow-growing soft tissue tumor that usually arises in the pelvis and perineal regions of women in reproductive age, with a marked tendency to local recurrence. Because of its rarity, it is often initially misdiagnosed. Surgical resection is the main treatment modali [...] ty of aggressive angiomyxoma. We describe a case of a vaginal aggressive angiomyxoma in a 47-year-old woman in which the diagnosis was only made after histological examination. The etiology, presentation, diagnosis and management of this rare tumor are outlined. Angiomyxoma of vulva and vagina refers to a rare disease. Pre-operative diagnosis is difficult due to rarity and absence of diagnostic features, but it should be considered in every mass in genital, perianal and pelvic region in a woman in the reproductive age. Thus, these cases should have complete radiological workup before excision, as pre-diagnosis can change the treatment modality and patient prognosis'.

  13. Primary malignant melanoma of the vagina: a case report

    International Nuclear Information System (INIS)

    A primary malignant melanoma of the vagina is a very rare gynecological malignant tumor. Its clinical behavior is more aggressive than that of cutaneous and vulvar melanomas. We present a case of a large sized primary melanoma of the lower third of the vagina, with a cervical lesion, in a 58-year-old postmenopausal woman. The patient was treated with conventional external radiation therapy and intracavitary radiotherapy (lCR), without surgical treatment. Although the primary lesion showed a partial response, the patient died of extensive metastases, which were found 4.5 months after the initial diagnosis. We suggest that shortening the treatment period, such as hypofractionated radiation therapy and surgical removal, and various systemic therapies for preventing early distant metastasis, are appropriate treatments for a primary malignant melanoma of the vagina, with a large tumor size

  14. Primary malignant melanoma of the vagina: a case report

    Energy Technology Data Exchange (ETDEWEB)

    Jang, Ji Young; Kim, Do Kang; Lee, Eun Hee [College of Medicine, Catholic Univ., Seoul (Korea, Republic of); Kim, Jun Sang [College of Medicine, Chungnam National Univ., Daejeon (Korea, Republic of)

    2003-09-01

    A primary malignant melanoma of the vagina is a very rare gynecological malignant tumor. Its clinical behavior is more aggressive than that of cutaneous and vulvar melanomas. We present a case of a large sized primary melanoma of the lower third of the vagina, with a cervical lesion, in a 58-year-old postmenopausal woman. The patient was treated with conventional external radiation therapy and intracavitary radiotherapy (lCR), without surgical treatment. Although the primary lesion showed a partial response, the patient died of extensive metastases, which were found 4.5 months after the initial diagnosis. We suggest that shortening the treatment period, such as hypofractionated radiation therapy and surgical removal, and various systemic therapies for preventing early distant metastasis, are appropriate treatments for a primary malignant melanoma of the vagina, with a large tumor size.

  15. MORPHOLOGICAL STUDY OF THE VAGINA OF THE Myocastor coypus (COYPU) ESTUDIO MORFOLOGICO DE LA VAGINA DE Myocastor coypus (COIPO)

    OpenAIRE

    Antonio E. Felipe; Alejandra Castro; Santiago S. Callejas; Jorge A. Cabodevila

    2000-01-01

    The Myocastor coypus (coypu) is a medium size rodent internationally considered as a species of economic interest because its fur. The aims of this work was realized the morphological study of the vagina of coypu. The vagina of sexually mature coypus appeared as a tubular organ, 10.25±1.40 cm long. The vaginal wall was very thin. It was composed by four layers: mucosa, submucosa, muscularis, and adventitia or serosa (according to the region). The lining epithelium of the mucosa was squamous s...

  16. Primary melanoma of the vagina. A clinical case

    OpenAIRE

    Isabel Alemany; Clara Olier; Judit Albareda

    2011-01-01

    Primary melanoma of the vagina is a rare neoplasm that appears in the 6th and 7th decades of life. It has a poor prognosis, for which there is no consensus regarding treatment; indeed, the literature describes a number of therapeutic options. This paper describes a patient with vaginal melanoma treated by local excision and immunotherapy.

  17. MORPHOLOGICAL STUDY OF THE VAGINA OF THE Myocastor coypus (COYPU) / ESTUDIO MORFOLOGICO DE LA VAGINA DE Myocastor coypus (COIPO)

    Scientific Electronic Library Online (English)

    Antonio E., Felipe; Alejandra, Castro; Santiago S., Callejas; Jorge A., Cabodevila.

    Full Text Available Myocastor coypus es un roedor de tamaño mediano, considerado internacionalmente como una especie de interés económico por sus cualidades peleteras. El estudio morfológico de su vagina reviste importancia en el marco de investigaciones de su fisiología reproductiva. La vagina de coipos sexualmente ma [...] duros se presentó como un órgano tubular, de 10,25 ± 1,40 cm de longitud. La pared vaginal fue muy delgada, distinguiéndose en ella cuatro túnicas: mucosa, submucosa, muscular y adventicia o serosa (según la región). Su epitelio de revestimiento era de tipo escamoso estratificado y aglandular. En la túnica muscular se diferenciaron dos capas de tejido muscular liso con abundancia de tejido conectivo. La serosa, conformada por tejido conectivo de aspecto denso, presentó numerosos y grandes vasos sanguíneos Abstract in english The Myocastor coypus (coypu) is a medium size rodent internationally considered as a species of economic interest because its fur. The aims of this work was realized the morphological study of the vagina of coypu. The vagina of sexually mature coypus appeared as a tubular organ, 10.25±1.40 cm long. [...] The vaginal wall was very thin. It was composed by four layers: mucosa, submucosa, muscularis, and adventitia or serosa (according to the region). The lining epithelium of the mucosa was squamous stratified and without glands. Two layers of smooth muscular tissue with abundance of connective tissue were differentiated in the muscularis. The tunica serosa, formed by connective tissue of dense aspect, had numerous big blood vessels

  18. MORPHOLOGICAL STUDY OF THE VAGINA OF THE Myocastor coypus (COYPU ESTUDIO MORFOLOGICO DE LA VAGINA DE Myocastor coypus (COIPO

    Directory of Open Access Journals (Sweden)

    Antonio E. Felipe

    2000-01-01

    Full Text Available The Myocastor coypus (coypu is a medium size rodent internationally considered as a species of economic interest because its fur. The aims of this work was realized the morphological study of the vagina of coypu. The vagina of sexually mature coypus appeared as a tubular organ, 10.25±1.40 cm long. The vaginal wall was very thin. It was composed by four layers: mucosa, submucosa, muscularis, and adventitia or serosa (according to the region. The lining epithelium of the mucosa was squamous stratified and without glands. Two layers of smooth muscular tissue with abundance of connective tissue were differentiated in the muscularis. The tunica serosa, formed by connective tissue of dense aspect, had numerous big blood vesselsMyocastor coypus es un roedor de tamaño mediano, considerado internacionalmente como una especie de interés económico por sus cualidades peleteras. El estudio morfológico de su vagina reviste importancia en el marco de investigaciones de su fisiología reproductiva. La vagina de coipos sexualmente maduros se presentó como un órgano tubular, de 10,25 ± 1,40 cm de longitud. La pared vaginal fue muy delgada, distinguiéndose en ella cuatro túnicas: mucosa, submucosa, muscular y adventicia o serosa (según la región. Su epitelio de revestimiento era de tipo escamoso estratificado y aglandular. En la túnica muscular se diferenciaron dos capas de tejido muscular liso con abundancia de tejido conectivo. La serosa, conformada por tejido conectivo de aspecto denso, presentó numerosos y grandes vasos sanguíneos

  19. Radiosterilisation of the vagina in therapeutic doses - does it exist

    International Nuclear Information System (INIS)

    The endogenous genital flora is a major source of infections of the female genital tract, especially in patients with cervical or endometrial cancer. Until recently the 'radiosterilisation of the vagina', respectively a prophylactic and/or therapeutic effect of irradiation (external highvoltage as well as intracavitary-radium) concerning infections was postulated in the literature. This theory was disproved in a prospective clinical and bacteriological study covering 48 patients with advanced cervical cancer undergoing primary intracavitary radium-irradiation and 38 patients with inoperable endometrical cancer, undergoing primary iridium-192-afterloading. Following intracavitary radium for cervical cancer some typical nosocomial pathogens like Streptococcus faecalis, Enterobacter, Klebsiella, Proteus and Pseudomonas were isolated significantly more frequently than before treatment. Likewise, the mean number of aerobic bacterial species increased significantly after irradiation. Also primary Ir-192 (afterloading) irradiation did not alter the frequency of isolation of the resident flora in endometrial cancer patients. Therefore, 'radiosterilisation' of the vagina as result of radiotherapy does not exist. (orig.)

  20. Interstitial radiotherapy of malignant tumors of the vagina

    International Nuclear Information System (INIS)

    A total of 65 patients with malignant tumors of the vagina aged 32 to 81 years were treated by interstitial radiotherapy. Out of the 65 subjects, 52 patients were irradiated with 60Co sources, and 13 patients with 252Cf sources. Fixing devices of three types were used which ensured practical implementation of interstitial radiotherapy in regard to tumor location, its shape, and volume. Complete tumor regression occurred in 54 patients (83.1%) and partial regression was observed in 9 patients (13.8%). Mild radiation reactions were found in 17 patients (26.1%). No effect was observed in 2 patients (3.1%). In one case a necrotic radiation ulcer developed. Based on the above data, the conclusion was drawn that interstitial radiotherapy represents the treatment of choice in malignant tumors of the vagina. (author). 6 figs., 2 tabs., 19 refs

  1. Management of radionecrosis of the vulva and distal vagina

    International Nuclear Information System (INIS)

    Twelve patients were seen between January 1983 and June 1989 with the clinical diagnosis of radionecrosis of the vulva or distal vagina. Seven patients received radiation for vulvar cancer, three for distal vaginal cancer, and two for recurrent endometrial cancer. No patient healed spontaneously and the mean delay in surgical therapy was 8.5 months. The radionecrotic site was treated with local therapy, radical local excision (with or without colostomy), or exenteration. The operative defect was closed primarily in three patients and covered with local flaps or myocutaneous flaps in seven patients. The two patients with local care still have radionecrotic ulcers. One of three patients who were closed primarily continues to have an ulcer. All other patients have healed satisfactorily except one who died after two attempts to correct the problem. Radionecrosis of the vulva and distal vagina should generally be treated surgically

  2. A case of postirradiated malignant fibrous histiocytoma of the vagina

    International Nuclear Information System (INIS)

    An unusual case of postirradiated malignant fibrous histiocytoma of the vagina in a 72-year-old female is reported. The tumor occurred in the radiation field 30 years after radical hysterectomy and preoperative radiation therapy (radium 5,200 mgh) for squamous cell carcinoma of the uterine cervix. She had been disease free for 30 years until she noticed a large mass in the vagina. Cytological study showed mainly two types of non-epithelial malignant cells; spindle-shaped fibroblast-like cells and histiocyte-like cells. Bizarre mono or multinucleated giant cells were often observed. The operative specimen revealed an arrangement composed of short or long spindle cells and vacuolated mononucleated and large multinucleated cells. The diagnosis was comfirmed by immunohistological and ultrastructural study. We have reviewed the literature on malignant fibrous histiocytoma occurring after radiation for cervical carcinoma. (author)

  3. Propranolol concentrations in plasma after insertion into the vagina.

    OpenAIRE

    Patel, L. G.; Warrington, S. J.; Pearson, R. M.

    1983-01-01

    Six healthy women participated in a study of the concentrations of propranolol achieved in plasma after insertion of the drug into the vagina. In four of the women the concentrations were also determined after administration by mouth. The area under the concentration curve for propranolol administered per vaginam was significantly greater than that after oral administration. There were small significant reduction in systolic blood pressure, pulse rate, and forced expiratory volume in one seco...

  4. Malignant peripheral nerve sheath tumor of the vagina

    International Nuclear Information System (INIS)

    Malignant peripheral nerve sheath tumors (MPNSTs) usually develop in major nerve trunks, giving rise to tumors in the proximal portions of the upper and lower extremities and trunk. The MPNSTs primarily occurring in the female genital tract are quite rare. We describe a case of MPNST of the vagina and discuss its diagnosis and treatment. This patient was treated definitively with radical local excision and is well with no signs of recurrence 2 years postoperatively. (author)

  5. Radiation therapy in primary carcinoma of the vagina

    International Nuclear Information System (INIS)

    The experiences with irradiation of 25 patients with primary carcinoma of the vagina are presented. The 3-year survival was 36 per cent despite the fact that most of the cases were advanced. Further improvements in survival may probably be achieved with extension of the radium implantation to paravaginal tissues. Choice and technique of treatment must be individualized. Surgery is limited to the more advanced cases with involvement of the bladder and rectum. (Auth.)

  6. A case of small cell carcinoma of the vagina

    OpenAIRE

    Ryosuke Tamura; Yoshihito Yokoyama; Asami Kabayashi; Yuuki Osawa; Tatsuhiko Shigeto; Masayuki Futagami; Hideki Mizunuma

    2013-01-01

    Primary small cell carcinoma of the vagina is quite rare, and a standard treatment has not been established yet. Herein, we report a case of an 81-year-old woman who was diagnosed with a vaginal tumor without continuity with the uterine cervix. Histopathological diagnosis indicated alveolar solid growth of nuclear chromatin-rich atypical cells with a high N/C ratio and a partially recognized rosette-like structure, suggesting a differentiated neuroendocrine system. Chromogranin A and synapto-...

  7. Malignant peripheral nerve sheath tumor of the vagina.

    OpenAIRE

    Jie Zhang; Yang Sun; Zhi-lan Peng

    2009-01-01

    ABSTRACT Malignant peripheral nerve sheath tumors (MPNSTs) usually develop in major nerve trunks, giving rise to tumors in the proximal portions of the upper and lower extremities and trunk. The MPNSTs primarily occurring in the female genital tract are quite rare. We describe a case of MPNST of the vagina and discuss its diagnosis and treatment. This patient was treated definitively with radical local excision and is well with no signs of recurrence 2 years postoperatively.

  8. Fibroepithelial polyps of the vagina: are they old granulation tissue polyps?

    OpenAIRE

    Halvorsen, T. B.; Johannesen, E.

    1992-01-01

    AIMS: To study the nature of fibroepithelial polyps of the vagina. METHODS: Sixty five fibroepithelial polyps of the vagina and 64 granulation tissue polyps diagnosed over 15 years were reviewed histologically. RESULTS: Cytologically benign multinucleated stromal cells were present in large numbers in 19 of the fibroepithelial polyps of the vagina (FEPV). Only one polyp contained atypical stromal cells, a high mitotic count, and abnormal mitoses and was indistinguishable from a malignant tumo...

  9. Endodermal sinus tumor of the vagina in children: A report of two cases

    OpenAIRE

    Gangopadhyay Mimi; Raha Kalpana; Sinha Swapan; De Anuradha; Bera Pranati; Pati Shyamapada

    2009-01-01

    Malignant tumors of the vagina in infants and children are rare, with primary germ cell tumor (endodermal sinus tumor [EST]) being rarer, which carries a dismal prognosis. This tumor is often clinically mistaken as botryoid rhabdomyosarcoma and, on histopathological examination, is often misdiagnosed as clear cell adenocarcinoma. Two cases of EST of the vagina in infants aged 9 and 17 months are reported. Both the patients presented with bleeding per vagina and clinically and by ultrasonograp...

  10. Leiomyosarcoma of the vagina: A rare entity with comprehensive review of the literature

    OpenAIRE

    Khosla, Divya; Patel, Firuza D.; Kumar, Ritesh; Gowda, Kiran K.; Nijhawan, Raje; Sharma, Suresh C.

    2014-01-01

    Primary malignant lesions of the vagina are uncommon, and vaginal sarcomas are even rarer. We describe a rare case of stage I, high-grade leiomyosarcoma of the vagina treated with combined modality treatment. A 39-year-old female presented with vaginal mass and underwent resection. Histopathological examination revealed atypical leiomyoma of the vagina with definite risk of recurrence. Eleven months later, she presented with a recurrent vaginal mass and underwent exploratory laparotomy with t...

  11. Radiation treatment of primary carcinoma of the vagina

    International Nuclear Information System (INIS)

    Patterns of failures after definitive radiation therapy were analyzed in 88 patients with primary carcinoma of the vagina treated between 1957 and 1975. The majority of the local failures in early stages of the disease (I, II and a few III) were due to inadequate treatment either by external beam therapy or brachytherapy. In some cases the inadequate treatments were unavoidable (previous radiation treatment) and in a few they were due to poor brachytherapy technique. Distant failures are still a problem and need to be given further attention. (orig.)

  12. Normal tissue tolerance to external beam radiation therapy: The vagina

    International Nuclear Information System (INIS)

    The vagina is a virtual cavity involved in sexual reproduction field. Due to its anatomical location, it may be exposed in whole or in part to ionizing radiation in external radiotherapy and/or brachytherapy of the pelvic region. This review aims to describe the vaginal acute and late side effects due to radiation, probably inadequately reported in the literature. Medline and PubMed literature searches were performed using the keywords -vaginal - radiotherapy - toxicity. The acute and late functional changes after external beam radiation consist mainly of drought. Their incidences are poorly described in the literature and the delivered doses even less. Recommendations are non-existent as the normal tissue complication probability (NTCP). Brachytherapy delivers high and heterogeneous doses, making it difficult to estimate the dose. The concomitant administration of chemotherapy appears to be a factor increasing the risk of toxicity. Modern techniques of conformal radiotherapy with modulated intensity appear to have little impact on this body. Only a maximum dose on each third of the vagina appears to be currently proposed to avoid the risk of side effects. (authors)

  13. Management of radiation injuries of vulva and vagina

    International Nuclear Information System (INIS)

    Background: Acute and late injuries of vulva and vagina are frequent and potentially serious complications in radiotherapy of gynecologic tumors. They still are reported poorly in literature. Methods: Based on a literature search a survey will be given of the modalities, which are used or recommended for prophylaxis or treatment of these radiation injuries. The principles of the different measures will be discussed with available study results. Results: Hygiene measures and the topical application of antimicrobial or granulation stimulating substances, which is mostly based on long standing clinical experience, are the principles of the treatment of acute reactions of vulva and vagina. The topical use of estrogen, which promotes proliferation of epithelium, is generally described in connection with treatment and prophylaxis of late radiation injuries. As a prophylaxis for the late reaction of vaginal stenosis, vaginal dilatation is recommended in literature. Conclusion: With the exception of a few reports on estrogen, there are no data about the effectiveness of the currently used medical substances. The local application of estrogen as prophylaxis of the acute reactions will therefore be examined in a prospective study. (orig.)

  14. Primary Small Cell Neuroendocrine Carcinoma of Vagina: A Rare Case Report

    OpenAIRE

    Parekh, Malay N.; Kapapura, Dhiren V.; Bhalodia, Jignasa N.

    2011-01-01

    Primary small cell neuroendocrine carcinoma of vagina is an extremely rare disease. There have been only 26 previously reported cases in literature. Here, we report a case of primary small cell neuroendocrine carcinoma of vagina. Immunohistochemistry (IHC) showed tumor cells positive for synaptophysin, chromogranin, and neuron-specific enolase (NSE).

  15. Urethral substitution with ileum in traumatic bladder neck-vagina fistula

    OpenAIRE

    Kannaiyan Lavanya; Sen Sudipta

    2009-01-01

    A five-year-old girl presented with post traumatic urinary incontinence secondary to rupture of the bladder neck into the vagina. Operative repair included a midline exposure with resection of the symphysis pubis, separation of the bladder neck from the vagina, repair of the torn bladder neck and urethral substitution with ileum. Normal continence and voiding was achieved.

  16. Primary malignant melanoma of the vagina: A case report and review of literature

    OpenAIRE

    Chaudhuri, Snehamay; Das, Diptimay; Chowdhury, Soham; Gupta, Anjan Das

    2013-01-01

    A 60 year old woman presented in gynecology department with bleeding per vagina and subsequently histotpathologically, it was diagnosed as malignant melanoma of the vagina. She underwent excision biopsy. On metastatic work-up, Positron emission tomography (PET) scan proved that she had distant metastasis and received palliative radiotherapy and chemotherapy, with temozolamide. She is alive after one year.

  17. Inseminación artificial de alpacas con semen colectado por aspiración vaginal y vagina artificial / Artificial insemination of alpacas with semen collected by vaginal aspiration and by artificial vagina

    Scientific Electronic Library Online (English)

    Virgilio, Alarcón B; Wilber, García V; P. Walter, Bravo.

    Full Text Available Semen de alpaca fue colectado por dos métodos: por aspiración de la vagina de la hembra después de la monta natural y con vagina artificial. El semen colectado fue evaluado y diluido con Tris tamponado, y luego usado en inseminacion artificial. Se trabajó con 160 alpacas hembras adultas de capacidad [...] reproductiva comprobada y 5 alpacas machos. Se colectó semen post cópula de los cinco machos en 10 hembras, y se hicieron 50 colecciones de semen con vagina artificial de estos machos, dos veces por semana. Se determinó volumen, motilidad, concentración espermática, porcentaje de espermatozoides vivos, viscosidad y color. Los resultados para semen colectado por aspiración de la vagina y con vaginal artificial fueron: volumen (3.6 y 1.5 mL), motilidad (73.4 y 69.0%), concentración espermática (75.2 y 80.3 millones/mL), espermatozoides vivos (75.3 y 70.8%), respectivamente, con diferencia entre métodos (p Abstract in english Semen from alpacas was collected by two methods: by aspiration from the female’s vagina following mating and with an artificial vagina. Semen was collected, evaluated and extended with Tris buffer, and then used in artificial insemination. Altogether 160 female alpacas with proven reproductive histo [...] ry and five males were used. Semen was collected by vaginal aspiration from 10 females using five males as semen donors; likewise, semen from the same males was collected with an artificial vagina twice a week 50 times. Volume, motility, spermatic concentration, live spermatozoa, viscosity and color was evaluated. Seminal characteristics of semen collected by aspiration and with an artificial vagina were: volume (3.6 and 1.5 mL), motility (73.4 and 69.0%), sperm concentration (75.2 and 80.3 million/mL), live spermatozoa (75.3 and 70.8%) respectively, with statistical difference between methods (p

  18. Almacenamiento de espermatozoides en la vagina de la lagartija vivípara Sceloporus torquatus (Sauria: Prhynosomatidae) / Sperm storage in the vagina of the viviparous lizard Sceloporus torquatus (Sauria: Prhynosomatidae)

    Scientific Electronic Library Online (English)

    Martín, MARTÍNEZ-TORRES.

    2009-12-01

    Full Text Available Las hembras de muchas especies de lagartijas tienen la capacidad de almacenar espermatozoides en un sistema de túbulos especiales presentes en la vagina. Sin embargo, en otras especies los espermatozoides se almacenan en el infundíbulo. Se utilizó una técnica sencilla y rápida para determinar sí la [...] vagina de Sceloporus torquatus tiene la capacidad de almacenar espermatozoides. En las hembras de esta especie, los espermatozoides son retenidos al menos 167 días en un sistema de túbulos especiales localizados en la vagina. La cantidad de espermatozoides presentes en los lavados vaginales disminuyó gradualmente a partir de diciembre y su desaparición ocurrió en la preñez tardía. Los espermatozoides ascienden al útero e infundíbulo antes de que ocurra la ovulación, sin embargo, en estos órganos no existen estructuras especiales para almacenar espermatozoides. Abstract in english Females of many lizard species are able to store sperm in a special system of tubules present in the vagina. However, in other species sperm storage occurs in the infundibulum. A quick and simple technique to determine if the vagina of Sceloporus torquatus has the capacity to store sperm was used. I [...] n this species the spermatozoa are retained at least during 167 days after mating in a special system of tubules located in the vagina. The amount of spermatozoa observed through vaginal flushing was reduced gradually from December on and the spermatozoa disappeared in late pregnancy. The spermatozoa reached the uterus and infundibulum before ovulation started; however, in these organs there are no special structures for sperm storage.

  19. Leiomyosarcoma of the vagina: A rare entity with comprehensive review of the literature.

    Science.gov (United States)

    Khosla, Divya; Patel, Firuza D; Kumar, Ritesh; Gowda, Kiran K; Nijhawan, Raje; Sharma, Suresh C

    2014-07-01

    Primary malignant lesions of the vagina are uncommon, and vaginal sarcomas are even rarer. We describe a rare case of stage I, high-grade leiomyosarcoma of the vagina treated with combined modality treatment. A 39-year-old female presented with vaginal mass and underwent resection. Histopathological examination revealed atypical leiomyoma of the vagina with definite risk of recurrence. Eleven months later, she presented with a recurrent vaginal mass and underwent exploratory laparotomy with total abdominal hysterectomy and bilateral salpingo-oophorectomy plus resection of recurrent tumor and partial vaginectomy. The detailed histopathological examination was suggestive of leiomyosarcoma of the vagina. The patient received adjuvant radiotherapy and chemotherapy. The patient is alive and disease-free 29 months postsurgery. Experience with vaginal leiomyosarcomas is limited. The optimal treatment methods have not yet been established because of the rarity of the tumor. We add another case of leiomyosarcoma of the vagina to the limited existing literature. PMID:25143892

  20. Definitive radiation therapy for squamous cell carcinoma of the vagina

    International Nuclear Information System (INIS)

    Purpose: To evaluate outcome and describe clinical treatment guidelines for patients with primary squamous cell carcinoma of the vagina treated with definitive radiation therapy. Methods and Materials: Between 1970 and 2000, a total of 193 patients were treated with definitive radiation therapy for squamous cell carcinoma of the vagina at The University of Texas M. D. Anderson Cancer Center. The patients' medical records were reviewed to obtain information about patient, tumor, and treatment characteristics, as well as outcome and patterns of recurrence. Surviving patients were followed for a median of 137 months. Survival rates were calculated using the Kaplan-Meier method, with differences assessed using log-rank tests. Results: Disease-specific survival (DSS) and pelvic disease control rates correlated with International Federation of Gynecology and Obstetrics (FIGO) stage and tumor size. At 5 years, DSS rates were 85% for the 50 patients with Stage I, 78% for the 97 patients with Stage II, and 58% for the 46 patients with Stage III-IVA disease (p = 0.0013). Five-year DSS rates were 82% and 60% for patients with tumors ?4 cm or >4 cm, respectively (p = 0.0001). At 5 years, pelvic disease control rates were 86% for Stage I, 84% for Stage II, and 71% for Stage III-IVA (p = 0.027). The predominant mode of relapse after definitive radiation therapy was local-regional (68% and 83%, respectively, for patients with stages I-II or III-IVA disease). The incidence of majorIII-IVA disease). The incidence of major complications was correlated with FIGO stage; at 5 years, the rates of major complications were 4% for Stage I, 9% for Stage II, and 21% for Stage III-IVA (p < 0.01). Conclusions: Excellent outcomes can be achieved with definitive radiation therapy for invasive squamous cell carcinoma of the vagina. However, to achieve these results, treatment must be individualized according to the site and size of the tumor at presentation and the response to initial external-beam radiation therapy. Brachytherapy plays an important role in the treatment of many vaginal cancers but should be carefully selected and applied to obtain optimal coverage of the target volume

  1. Radiation Therapy of Primary Carcinoma of the Vagina

    International Nuclear Information System (INIS)

    A retrospective study was carried out of 20 patients with histologically proven invasive carcinoma of the vagina from 1979 to 1993; 17 cases with curative primary radiotherapy and three cases with postoperative radiotherapy. The five and ten year overall survival rates were 79% and 53%, respectively. Survival was strongly correlated with stage. Five year survival rates of stage I, stage II, and stage III, IV were 100%, 78%, and 0%, respectively. Eight patients experienced recurrences; five within the irradiated volume, two distant metastasis, and one combined both local and distant metastasis. There was no significant late complication. From these data, radiation is effective in the management of the vaginal cancer patients and optimum treatment modality and total dose recommendation are made

  2. Malignant melanoma of the vagina: a report of 2 cases

    International Nuclear Information System (INIS)

    Primary malignant melanoma of the vagina is an extremely rare genital neoplasm occurring mainly in postmenopausal women. It has a worse prognosis than cutaneous melanomas, because of the high rate of locoregional recurrences and rapid systemic dissemination. In the past, radical surgical extirpation as the primary management had been recommended to improve loco-regional control, and possibly overall survival. However, the prognosis was poor in spite of such a radical approach. Recently, more conservative treatment such as wide local excision combined with adjuvant high-dose fraction radiotherapy seems to have promising results. Primary radiation therapy could be served as an alternative to surgery for patients with lesion less than 3 cm in diameter. We report 2 cases of primary vaginal malignant melanoma treated with radiotherapy

  3. Radiation therapy in primary carcinoma of the vagina

    International Nuclear Information System (INIS)

    A retrospective analysis of 32 patients with carcinoma of the vagina treated with curative radiotherapy between 1965 and 1981 is presented. Squamous cell carcinoma was the most common histologic type, found in 78% of the patients. Patients were staged according to the FIGO system. Stage I and II disease was found in 8 and 18 patients, respectively. Six patients had either Stage III or IV disease. The absolute survival rate was 100% for Stage I and 72% for Stage II patients. The pattern of failure was analyzed. All patients who failed had done so within 14 months of completion of treatment. Treatment failure in the pelvis occurred only in 16% of the patients with early disease (Stages I and II) while 81% of the patients with late stage had failed in the pelvis

  4. Malignant melanoma of the vagina: a report of 2 cases

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Ok Bae; Kim, Jin Hee; Jung, Young Yeon; Cho, Chi Heum; Choi, Tae Jin [Dongsan Medical Center, School of Medicine, Keimyung University, Daegu (Korea, Republic of)

    2005-06-15

    Primary malignant melanoma of the vagina is an extremely rare genital neoplasm occurring mainly in postmenopausal women. It has a worse prognosis than cutaneous melanomas, because of the high rate of locoregional recurrences and rapid systemic dissemination. In the past, radical surgical extirpation as the primary management had been recommended to improve loco-regional control, and possibly overall survival. However, the prognosis was poor in spite of such a radical approach. Recently, more conservative treatment such as wide local excision combined with adjuvant high-dose fraction radiotherapy seems to have promising results. Primary radiation therapy could be served as an alternative to surgery for patients with lesion less than 3 cm in diameter. We report 2 cases of primary vaginal malignant melanoma treated with radiotherapy.

  5. Radiation-induced morphological changes in the vagina

    International Nuclear Information System (INIS)

    Background and purpose: Treatment-induced chronic vaginal changes after definitive radio(chemo)therapy for locally advanced cervical cancer patients are reported as one of the most distressing consequences of treatment, with major impact on quality of life. Although these vaginal changes are regularly documented during gynecological follow-up examinations, the classic radiation morbidity grading scales are not concise in their reporting. The aim of the study was therefore to identify and qualitatively describe, on the basis of vaginoscopies, morphological changes in the vagina after definitive radio(chemo)therapy and to establish a classification system for their detailed and reproducible documentation. Patients and methods: Vaginoscopy with photodocumentation was performed prospectively in 22 patients with locally advanced cervical cancer after definitive radio(chemo)therapy at 3-24 months after end of treatment. All patients were in complete remission and without severe grade 3/4 morbidity outside the vagina. Results: Five morphological parameters, which occurred consistently after treatment, were identified: mucosal pallor, telangiectasia, fragility of the vaginal wall, ulceration, and adhesions/occlusion. The symptoms in general were observed at different time points in individual patients; their quality was independent of the time of assessment. Based on the morphological findings, a comprehensive descriptive and semiquantitative scoring system was developed, whititative scoring system was developed, which allows for classification of vaginal changes. A photographic atlas to illustrate the morphology of the alterations is presented. Conclusion: Vaginoscopy is an easily applicable, informative, and well-tolerated procedure for the objective assessment of morphological vaginal changes after radio(chemo)therapy and provides comprehensive and detailed information. This allows for precise classification of the severity of individual changes. (orig.)

  6. Internal motion of the vagina after hysterectomy for gynaecological cancer

    International Nuclear Information System (INIS)

    Background and purpose: The purpose of this study was to investigate position changes of the vagina after hysterectomy for early stage cervical or endometrial cancer and their impact on CTV-PTV margins. We also studied their correlation with surrounding organ filling. Materials and methods: Fifteen patients underwent T2-weighted MR scans before and weekly during the course of their EBRT. The vaginal CTVs and the surrounding organs were delineated. PTV margins were derived from the boundaries of the CTVs in the main directions and correlated with changes in the volumes of organs at risk. Additionally we investigated the impact of margin sizes on CTV coverage. Results: The vaginal CTVs change their position in the pelvis during time with a maximum in anterior-posterior direction. The 95% confidence level was 2.3 cm into the anterior or posterior direction, 1.8 cm to left or right and 1.5 cm towards the cranial. With a homogenous 1.5 cm CTV-PTV margin ?5% inadequately covered vaginal CTV was seen in only 3.3% of the measurements. This increased to 20.6% with a margin of 1.0 cm. Concerning the impact of organ filling on vaginal position changes we found the only significant correlation with rectal volume and shift of the vagina towards anterior-posterior. Conclusion: To accommodate the changes in the position of the vaginal CTV inhomogeneous PTV margins should be generated with the largest size in the anterior-posterior direction. The position shifts were only weakly re The position shifts were only weakly related to the volume of the rectum and not at all to the volumes of other parts of the bowel and the bladder.

  7. Radiation-induced morphological changes in the vagina

    Energy Technology Data Exchange (ETDEWEB)

    Kirchheiner, K.; Fidarova, E.; Schmid, M.P.; Sturdza, A.; Kranz, A.; Poetter, R. [Medical Univ. of Vienna (Austria). Dept. of Radiation Oncology; Nout, R.A. [University Medical Center Leiden (Netherlands). Dept. of Clinical Oncology; Wiebe, E. [Alberta Univ., Cross Cancer Institute, Edmonton, AB (Canada). Dept. of Radiation Oncology; Polterauer, S. [Medical Univ. of Vienna (Austria). Dept. of General Gynecology and Gynecologic Oncology; Doerr, W. [Medical Univ. of Vienna (Austria). Dept. of Radiation Oncology; Medical Univ. of Vienna (Austria). Christian Doppler Laboratory for Medical Radiation Research for Radiation Oncology

    2012-11-15

    Background and purpose: Treatment-induced chronic vaginal changes after definitive radio(chemo)therapy for locally advanced cervical cancer patients are reported as one of the most distressing consequences of treatment, with major impact on quality of life. Although these vaginal changes are regularly documented during gynecological follow-up examinations, the classic radiation morbidity grading scales are not concise in their reporting. The aim of the study was therefore to identify and qualitatively describe, on the basis of vaginoscopies, morphological changes in the vagina after definitive radio(chemo)therapy and to establish a classification system for their detailed and reproducible documentation. Patients and methods: Vaginoscopy with photodocumentation was performed prospectively in 22 patients with locally advanced cervical cancer after definitive radio(chemo)therapy at 3-24 months after end of treatment. All patients were in complete remission and without severe grade 3/4 morbidity outside the vagina. Results: Five morphological parameters, which occurred consistently after treatment, were identified: mucosal pallor, telangiectasia, fragility of the vaginal wall, ulceration, and adhesions/occlusion. The symptoms in general were observed at different time points in individual patients; their quality was independent of the time of assessment. Based on the morphological findings, a comprehensive descriptive and semiquantitative scoring system was developed, which allows for classification of vaginal changes. A photographic atlas to illustrate the morphology of the alterations is presented. Conclusion: Vaginoscopy is an easily applicable, informative, and well-tolerated procedure for the objective assessment of morphological vaginal changes after radio(chemo)therapy and provides comprehensive and detailed information. This allows for precise classification of the severity of individual changes. (orig.)

  8. High-dose-rate brachytherapy for cervical carcinoma patients with narrow vagina

    International Nuclear Information System (INIS)

    We retrospectively analyzed cervical cancer patients with narrow vagina treated by high-dose-rate (HDR) brachytherapy followed by external beam irradiation. Fifty patients were treated with radical radiotherapy between 1992 and 1999 at the National Tokyo Medical Center. All patients received 30 Gy of external whole pelvic irradiation and 20 Gy of pelvic irradiation with a central shield. After 30 Gy of whole pelvic irradiation, 24 Gy of fractionated brachytherapy was applied with a tandem and ovoids, non-rigid type developed in the Cancer Institute, according to the Manchester method. Nineteen patients with a narrow vagina of less than 40 mm in width were compared with 31 other patients (control group). The 5-year cumulative survival rates were 56% in the patients with a narrow vagina and 53% in the control group (P=0.6008). The control rate in the pelvis was not significantly different between the two groups. The cumulative rate of rectal complications of the patients with a narrow vagina was more frequent than the control group (58% vs 29%) (P=0.0924). Severe rectal bleeding was also more frequent in the patients with a narrow vagina. The estimated maximal dose of the rectal wall was significantly higher in patients with a narrow vagina. This result suggests that a lower brachytherapy dose is necessary for patients with narrow vagina considering the rectal sequelae in the case of using our methods. (author)

  9. High-dose-rate brachytherapy for cervical carcinoma patients with narrow vagina

    Energy Technology Data Exchange (ETDEWEB)

    Yorozu, Atsunori; Toya, Kazuhito; Kawase, Takatugu [National Tokyo Medical Center, Tokyo (Japan); Dokiya, Takushi [Saitama Medical Coll., Moroyama (Japan)

    2002-06-01

    We retrospectively analyzed cervical cancer patients with narrow vagina treated by high-dose-rate (HDR) brachytherapy followed by external beam irradiation. Fifty patients were treated with radical radiotherapy between 1992 and 1999 at the National Tokyo Medical Center. All patients received 30 Gy of external whole pelvic irradiation and 20 Gy of pelvic irradiation with a central shield. After 30 Gy of whole pelvic irradiation, 24 Gy of fractionated brachytherapy was applied with a tandem and ovoids, non-rigid type developed in the Cancer Institute, according to the Manchester method. Nineteen patients with a narrow vagina of less than 40 mm in width were compared with 31 other patients (control group). The 5-year cumulative survival rates were 56% in the patients with a narrow vagina and 53% in the control group (P=0.6008). The control rate in the pelvis was not significantly different between the two groups. The cumulative rate of rectal complications of the patients with a narrow vagina was more frequent than the control group (58% vs 29%) (P=0.0924). Severe rectal bleeding was also more frequent in the patients with a narrow vagina. The estimated maximal dose of the rectal wall was significantly higher in patients with a narrow vagina. This result suggests that a lower brachytherapy dose is necessary for patients with narrow vagina considering the rectal sequelae in the case of using our methods. (author)

  10. The present-day technologies of brachytherapy for primary and metastatic carcinoma of the vagina

    International Nuclear Information System (INIS)

    Results of brachytherapy of 133 patients with primary vaginal carcinoma, 137 - with cervical metastasis into the vagina, and 132 cases of endometrial metastasis into the vagina, and 132 cases of endometrial metastasis into the vagina are presented. Recommendations based on a detailed analysis of isodose distribution versus the applicator type and radiation source used are given. Annular colpostat using 137cesium radiation form the Selectron NMD/SMD installation and 197indium radiation from the MicroSelectron unit produces the maximum mean reference isodose. Uniform distribution of 100 % isodose in exophytic and mixed neoplasms and the best mucosal focus and applicator volume-target volume ratio are obtained

  11. The irradiation tolerance dose of the proximal vagina

    International Nuclear Information System (INIS)

    Purpose: The purpose of this investigation was to determine the irradiation tolerance level and complication rates of the proximal vagina to combined external irradiation and low dose rate (LDR) brachytherapy. Also, the mucosal tolerance for fractionated high dose rate (HDR) brachytherapy is further projected based on the biological equivalent dose (BED) of LDR for an acceptable complication rate. Materials and methods: Two hundred seventy-four patients with stages I-IV cervical carcinoma treated with irradiation therapy alone from 1987 to 1997 were retrospectively reviewed for radiation-associated late sequelae of the proximal vagina. All patients received LDR brachytherapy and 95% also received external pelvic irradiation. Follow-up ranged from 15 to 126 months (median, 43 months). The proximal vagina mucosa dose from a single ovoid (single source) or from both ovoids plus the tandem (all sources), together with the external irradiation dose, were used to derive the probability of a complication using the maximum likelihood logistic regression technique. The BED based on the linear-quadratic model was used to compute the corresponding tolerance levels for LDR or HDR brachytherapy. Results: Grades 1 and 2 complications occurred in 10.6% of patients and Grade 3 complications occurred in 3.6%. There were no Grade 4 complications. Complications occurred from 3 to 71 months (median, 7 months) after completion of irradiation, with over 60% occurring in the first year. By over 60% occurring in the first year. By logistic regression analysis, both the mucosal dose from a single ovoid or that from all sources, combined with the external irradiation dose, demonstrate a statistically significant fit to the dose response complication curves (both with P=0.016). The single source dose was highly correlated with the all source dose with a cross-correlation coefficient 0.93. The all source dose was approximately 1.4 times the single source dose. Over the LDR brachytherapy dose rate range, the complication rate was relatively stable to small variations of the underlying tumor biological characteristics and the dose rate. The complication rates change approximately an absolute 1% over the range of the alpha-beta ratio (?/?) from 2 to 4 Gy and repair constant (?) of 0.46/h to 0.60/h. The complication rates increased an absolute 2% over the mucosa dose rate from 1.75 to 3.50 Gy/h. They markedly increased as the dose rate increased above 3.00 Gy/h as in HDR brachytherapy. The projected HDR Grade 3 tolerance varied from 25 Gy for one fraction to 57 Gy for six fractions in addition to 20 Gy external irradiation for nominal 3-5% complication rates. The traditional LDR tolerance dose of 150 Gy was shown to yield nominal 11% and 4% Grades 1 and 2 and Grade 3 sequelae, respectively. Conclusions: The traditional 150 Gy LDR tolerance dose (single source plus external irradiation) can be relaxed to 175 Gy or equivalently a full mucosal dose of 238 Gy (all sources plus external irradiation) for a nominal 5% Grade 3 complication rate. Higher fractionation is necessary with four to six fractions in HDR therapy for similar rates of sequelae. The mucosal surface dose from a single ovoid, which can be readily computed, remains a convenient tolerance check for treatment planning purposes

  12. Carcinoma of vagina 10 or more years following pelvic irradiation therapy

    International Nuclear Information System (INIS)

    Gynecologic cancer records of 4,238 patients treated between 1956 and 1974 were reviewed. Sixteen patients developed neoplasia in the cervix or vagina 10 or more years following pelvic irradiation. Three patients had squamous carcinoma in situ; the other 13 patients had invasive squamous cancer involving the upper vagina. Only 1.26 percent of invasive carcinoma of the cervix treated by radiation therapy from 1956 to 1966 presented with a late or recurrent or new primary tumor involving the vagina or cervix 10 or more years after primary treatment. The authors conclude that the risk of developing radiation-induced carcinoma in the upper vagina or cervix following pelvic irradiation is low. Follow-up Pap smears are indicated for all patients treated for cervical or vaginal malignancies by radiation therapy in order to detect vaginal neoplasia as well as recurrent carcinoma of the cervix

  13. Cytological Diagnosis of Small Cell Carcinoma of Vagina - A Diagnostic Dilemma

    OpenAIRE

    Yelikar, B. R.; Shettar, Savita S.; Mahesh Kumar U; Potekar, R. M.

    2013-01-01

    Small cell carcinoma is a neuroendocrine tumour, mainly arises in lung accounting for 20%of cases. In extra pulmonary sites it accounts for 5% of cases. Among gynaecological malignancies it accounts for 1-2% of cases, common sites are cervix, endometrium, ovary, vagina, vulva in decreasing frequencies. Small cell carcinoma is extremely uncommon in vagina.There are only 26 cases reported in the literature. Here we are reporting 27 th case. Because of its rarity the chances of missing the dia...

  14. Contrast vaginography is more accurate than the radiopaque rod for localization of the vagina

    International Nuclear Information System (INIS)

    Purpose: To compare the radiopaque vaginal rod method with contrast vaginography in localization of the vagina. Methods and Materials: In 25 female patients who needed pelvic radiotherapy, both our standard localization procedure using the vaginal rod and a localization procedure using contrast vaginography were performed. As a rod can change the position of the vagina, contrast vaginography was considered to display the true anatomic position of the vagina. The corresponding rod and nonrod X-rays of each patient were compared. The distance from the true vaginal apex to the displaced vaginal apex (= the top of the rod) was measured in the sagittal plane. This distance was called the inaccuracy of the rod method. Furthermore, the size of the vaginal vault was measured using the contrast vaginography. Results: The median inaccuracy of the rod method was 13 mm (range 2 to 24 mm). The maximal width of the vagina ranged from 24 to 68 mm in the frontal plane (median 39 mm) and from 3 to 22 mm in the sagittal plane (median 10 mm). Conclusion: The rod method is not accurate to localize the vagina. Furthermore, the rod gives no information on the actual size of the vaginal vault. Contrast vaginography is the method of choice to localize the vagina.

  15. Results of radiation therapy of squamous cell carcinoma of vagina

    International Nuclear Information System (INIS)

    Over a period from 1962 to 1982, 31 patients with squamous cell carcinoma in the vagina were treated by irradiation at National Cancer Center Hospital, Tokyo. Of them, 15 patients (48.4%) were over 60 years old. Treatment was done by external irradiation alone or a combination of external and intracavitary or interstitial irradiation. The lesions were classified into stages of the FIGO system. Stage I was found in 11 cases (35.5%), Stage II in 11 cases (35.5%), Stage III in 7 cases (22.6%) and Stage IVa in 1 case (3.2%). Serious complication after treatment was observed in 5 cases (16.1%) which consisted of 2 cases of rectovaginal fistula and one case of rectal constriction, one case of intestinal necrosis and one case of rectal ulcer. Local and pelvic failure was noted in 6 cases (19.4%) which were treated by reirradiation. Prognosis was poor in all cases, except one which was in Stage I. Some subsequent surgical procedures were required for further treatment in those cases. The 5-year survival rates by stage were as follows: 90% (9/10) for cases of Stage I, 22.2% (2/9) for cases of Stage II, 16.7% (1/6) for cases of Stage III and 0% (0/1) for case of Stage IVa. (author)

  16. Congenital absence of the vagina with a functioning uterus

    International Nuclear Information System (INIS)

    A functioning uterus may be present in 5 to 10 % of the patients with congenital absence of the vagina. The proper treatment for these patients depends on accurate pre-operative diagnosis on whether or not a cervix is present, because the mode of operation should be selected according to the type of abnormality. Ultrasonography or X-ray CT scan will not always be useful to answer this question. We encountered a 15-year-old female with cyclic lower abdominal pain and the failure of onset of menstruation. The external genitalia were normal except for the absence of the vaginal opening. Ultrasonography and X-ray CT scan revealed the presence of both uterine corpus and hematocolpos, but no definite findings were obtained on the integrity of the cervix. By using NMR-CT scan, we found a hematocolpos, properly developed uterine cervix and corpus above it. We treated the patient by preserving the uterine function and the potential for pregnancy in the future. NMR-CT scan seems more useful in some cases for diagnosis of pelvic mass than ultrasonography and X-ray CT scan. (author)

  17. Longitud de vagina, hiato genital y cuerpo perineal en mujeres nulíparas / Lengh of vagina, genital hiatus and perineal body in nulliparae

    Scientific Electronic Library Online (English)

    Fernando, Méndez.

    2015-01-01

    Full Text Available Objetivo: Estimar la longitud promedio de vagina, del hiato genital y cuerpo perineal en mujeres nulíparas. Diseño: Estudio descriptivo transversal con muestreo por conveniencia. Institución: Departamento de Ginecología y Obstetricia, Hospital Nacional Cayetano Heredia, Lima, Perú. Participantes: Mu [...] jeres nulíparas. Métodos: En 85 mujeres nulíparas atendidas en el Hospital entre enero y marzo 2014, en edad fértil, que habían iniciado relaciones coitales vaginales y que requerían evaluación ginecológica, se realizó medición del peso y talla. En posición de litotomía, se midió con un hisopo milimetrado la longitud total de la vagina, hiato genital y el cuerpo perineal. Las mediciones fueron realizadas por un solo examinador. La participación fue completamente voluntaria y con firma de consentimiento informado. Principales medidas de resultados: Longitud total de la vagina, hiato genital y el cuerpo perineal. Resultados: La media de la longitud total de vagina fue 8,1 ± 1,4 cm (DE), del hiato genital 2,2 ± 0,5 cm (DE) y del cuerpo perineal 2,3 ± 0,5 cm (DE). Conclusiones: Las medidas estimadas no difieren con resultados de estudios internacionales. Se requiere estudiar una mayor muestra de pacientes de las diferentes regiones para tener un estimado más representativo de estas medidas en pacientes nulíparas del Perú. Abstract in english Objectives: To determine vaginal, genital hiatus and perineal body length in nulliparous women. Design: Cross-sectional descriptive study with convenience sample. Setting: Department of Obstetrics and Gynecology, Hospital Nacional Cayetano Heredia, Lima, Peru. Participants: Nulliparous women. Method [...] s: From January through March 2014 in 85 nulliparous women in childbearing age who had coital sex and required gynecological evaluation, weight and height were obtained and length of vagina, genital hiatus and perineal body were measured with a graph swab in lithotomy position. Measurements were obtained by one single examiner. Participation was voluntary with signed informed consent. Main outcome measures: Length of vagina, genital hiatus and perineal body. Results: Average length of patients’ vagina was 8.1 ± 1.4 cm (SD), genital hiatus 2.2 ± 0.5 cm (SD), and perineal body 2.3 ± 0.5 cm (SD). Conclusions: Measures obtained did not differ from international studies. A broad population study is suggested to better estimate these measures in nulliparous Peruvian women.

  18. LASER EN EL TRATAMIENTO DE LA NEOPLASIA INTRAEPITELIAL DE VAGINA

    Scientific Electronic Library Online (English)

    Roberto, Yazigi I; Tulio, Rodríguez A; Luis, Contreras M.

    Full Text Available Objetivo: Presentar la experiencia en el tratamiento de la neoplasia intraepitelial de vagina (VAIN) utilizando el láser de CO2. Método: 19 pacientes con el diagnóstico histológico de VAIN fueron tratadas con esta técnica. Se utilizó un diámetro del punto de helio-neón de 1,5 a 2 mm y un poder de de [...] nsidad de 400 a 500 W/cm². Toda la lesión detectable más un margen de al menos 5 mm de tejido circundante aparentemente normal fueron vaporizados a una profundidad de 2 mm. Resultados: 12 de las 14 pacientes evaluables lograron una respuesta completa inicial (86%), de éstas 12 hubo 2 recidivas posteriores (17%), obteniendo una curación en 10 de las 14 evaluables (71%). No hubo complicaciones y se preservó una función vaginal normal. Conclusión: La vaporización con láser es una buena modalidad terapéutica en VAIN, particularmente en mujeres jóvenes en que se ha descartado razonablemente la coexistencia de cáncer invasor Abstract in english Objective: To describe our experience in the treatment of vaginal intra-epithelial neoplasia (VAIN) with the use of CO2 laser. Method: Nineteen patients with the diagnosis of VAIN were treated by this technique. We used a spot size of 1.5 to 2 mm and a power density of 400 to 500 W/cm². The entire l [...] esion in addition to at least a 5 mm margin of adjacent tissue were vaporized to a depth of 2 mm. Results: 12 of 14 evaluable patients had an initial complete response (86%), of these 12, there were 2 recurrences (17%), obtaining a 71% cure rate (10/14). There were no complications and preservation of normal vaginal function. Conclusion: Laser vaporization is a very good treatment modality, particularly in young women in whom the co-existence of invasive malignancy has been ruled out

  19. Exclusive radiotherapy for primary squamous cell carcinoma of the vagina

    International Nuclear Information System (INIS)

    Purpose: To retrospectively analyze results of external beam therapy (EBT) with brachytherapy (BT) for primary vaginal squamous cell carcinoma (PVSCC). Materials and methods: From 1970 to 2001, 91 patients were included. FIGO stages were: I (29%), II (38%), III (29%) and IVa (4%). EBT delivered a median total dose of 50 Gy to the pelvis. BT was performed with a customized intra-vaginal applicator and in 36% of applications combined endocavitary and interstitial BT. ICRU Report 38 parameters were reported. Results: The 5-year cause specific survival (CSS) rates were: 83% for stage I, 76% for stage II, 52% for stage III, and 2 of the 4 stage IVa patients died 9 and 36 months after treatment. The 5-year pelvis control rates were: 79% for stage I and II and 62% for stage III. Recurrences as a first event were local only in 68% of cases, nodal only in 10%, metastatic only in 13% and combined in 9%. In multivariate analysis: stage (I and II versus II and IV), response to EBT (evaluated at BT), and the number of BT applications were statistically significant for CSS. Grade 2-3 toxicities were as follows (Franco-Italian Glossary): rectum (n = 3), sigmoid colon and small bowel (n = 8), bladder (n = 5), ureter (n = 4) and vagina (n = 13). Anterior location of the tumor increased bladder toxicity (p = 0.01) and total reference air kerma was higher in patients who experienced grade 2-3 urinary or digestive toxicity (p = 0.03). Conclusion: EBT with BT is an effective treatment for EBT with BT is an effective treatment for patients with stage I-II PVSCC. The incidence and severity of late toxicity were relatively low. Recent advances in the treatment of cervix carcinoma emphasize the need for concomitant radio-chemotherapy in stages III-IV and the use of MRI for treatment planning

  20. Primary carcinoma of the vagina: Tata Memorial Hospital experience

    International Nuclear Information System (INIS)

    Purpose: Carcinoma of the vagina is a rare gynecological malignancy comprising approximately 2% of all the gynecological malignancies. We have analyzed the treatment outcome of the patients treated at the Tata Memorial Hospital from January 1984 to December 1993. Methods and Materials: In this 10-year period, 134 patients of primary vaginal cancers were registered at our hospital. Of these, 75 patients received complete treatment and are analyzed. Results: Disease-free survival (DFS) for the whole group is 50%, and overall survival (OAS) is 60%. Most locoregional recurrences and distant failures are noted in the 2 years following treatment. DFS at 5 years is as follows: Stage I (5 patients), Stage IIA (37 patients), Stage IIB (15 patients), Stage III (14 patients), and Stage IV (4 patients); are 40%, 55%, 60%, 50%, and 25%, respectively. The DFS for patients with complete response (42 patients) to external radiation at 5 years is 68%, with partial response (25 patients) is 35%, and with poor or no response (6 patients) is 18% (p 0.0000). We observed that brachytherapy was an important part of the treatment, and patients who received brachytherapy (59 patients), either with a vaginal intracavitary applicator (30 patients) or interstitial implant (29 patients) had a DFS of 53% and 56%, respectively, while 15 patients who received external radiation alone had a DFS of 30%. Patients receiving brachytherapy within 4 weeks of external radiation had a DFS of 60% as compared al radiation had a DFS of 60% as compared to 30% when the interval was more than 4 weeks. Conclusion: The factors indicating prognosis are: site and extent of involvement, presence of lymph nodes at presentation, technique of brachytherapy, and interval between external radiation and brachytherapy

  1. Non-Diethylstilbestrol-Associated Primary Clear Cell Carcinoma of the Vagina: Two Case Reports with Immunohistochemical Studies and Literature Review

    OpenAIRE

    Mufti, Shagufta T.; Ali, Hiba Hassan

    2014-01-01

    Primary clear cell adenocarcinomas most commonly involve the genitourinary system, including the vagina. Previously, primary clear cell adenocarcinomas of the vagina have been discussed within the context of prenatal exposure to diethylstilbestrol. Due to its widely proven role in the development of this carcinoma, administration of diethylstilbestrol is prohibited. We present two cases of non-diethylstilbestrol-associated primary clear cell adenocarcinoma of the vagina from the archives of t...

  2. ALMACENAMIENTO DE ESPERMATOZOIDES EN LA VAGINA DE LA LAGARTIJA VIVÍPARA SCELOPORUS TORQUATUS (SAURIA: PRHYNOSOMATIDAE

    Directory of Open Access Journals (Sweden)

    Mart\\u00EDn MART\\u00CDNEZ-TORRES

    2009-01-01

    Full Text Available Las hembras de muchas especies de lagartijas tienen la capacidad de almacenar espermatozoides en un sistema de túbulos especiales presentes en la vagina. Sin embargo, en otras especies los espermatozoides se almacenan en el infundíbulo. Se utilizó una técnica sencilla y rápida para determinar sí la vagina de Sceloporus torquatus tiene la capacidad de almacenar espermatozoides. En las hembras de esta especie, los espermatozoides son retenidos al menos 167 días en un sistema de túbulos especiales localizados en la vagina. La cantidad de espermatozoides presentes en los lavados vaginales disminuyó gradualmente a partir de diciembre y su desaparición ocurrió en la preñez tardía. Los espermatozoides ascienden al útero e infundíbulo antes de que ocurra la ovulación, sin embargo, en estos órganos no existen estructuras especiales para almacenar espermatozoides.

  3. Imaging of the vagina and vulva; Aspectos de imagem das lesoes vulvo-vaginais

    Energy Technology Data Exchange (ETDEWEB)

    Souza, Luis Ronan Marquez Ferreira de; Szejnfeld, Jacob [Universidade Federal de Sao Paulo (UNIFESP/EPM), SP (Brazil). Dept. de Diagnostico por Imagem]. E-mail: luisronan@gmail.com; Borges, Leonardo Romualdo; Rosalen Junior, Roberto Antonio [Universidade Federal do Triangulo Mineiro (UFTM), Uberaba, MG (Brazil); Signorini Filho, Roney Cesar; Marques, Renato Moretti; Nicolau, Sergio Mancini [Universidade Federal de Sao Paulo (UNIFESP/EPM), SP (Brazil). Disciplina de Oncoginecologia; Goldman, Suzan Menasce [Universidade Federal de Sao Paulo (UNIFESP/EPM), SP (Brazil). Dept. de Diagnostico por Imagem

    2006-10-15

    In gynecological daily practices, the vulva and vagina are examined during physical examination, however there are situations where this is not possible or it is needed to determine the extension of an injury through imaging methods. The magnetic resonance imaging is an excellent cross-sectional modality for evaluation the alterations of vulva and vagina due its multiplanar evaluation and high tecidual contrast. Other cross-sectional modalities are ultrasound and enhanced computed tomography. This paper intends to give an overview of vaginal and vulvar pathology that can be identified by the radiologist. (author)

  4. Carcinoma of the vulva and vagina in patients irradiated for carcinoma of the cervix

    International Nuclear Information System (INIS)

    Six patients with carcinoma of the vulva and 3 with carcinoma of the vagina following radiation therapy for cancer of the cervix were analyzed. The interval between irradiation and diagnosis of the second tumor varied from 5 to 23 years. Despite the lack of having detailed information on irradiation factors in all patients, circumstantial evidence from this study suggests that radiation therapy may have contributed to the development of carcinoma of the vulva and vagina in some of the patients. Close follow-up patients treated for squamous carcinoma of the genital tract must emphasize inspection for new lesions. The incidences previously reported in the literature are also reviewed for comparison. (author)

  5. Pathomorphologic Investigations on the Genital System of Ewes II.Uterus, Cervix and Vagina

    OpenAIRE

    Karadas?, Erkan; Ti?murkaan, Necati

    2001-01-01

    This study was carried out to determine the pathomorphologic changes and the incidence of these changes in the uterus, cervix, vagina and related ligaments of ewes slaughtered at Elaz?? abattoirs. For this purpose,the genital organs of 6100 ewes from different breeds and ages were examined.There were pathomorphologic changes in 274 cases (4.49%)in the uterus,70 cases (1.14%)in the cervix,and 61 cases (1.00%)in the vagina.Inflammatory changes were primarily lesions (2.68%)observed in the...

  6. Melanoma amelanótico primario de vagina: reporte de un caso y revisión de la literatura / Primary amelanotic melanoma of the vagina: a case report and literature review

    Scientific Electronic Library Online (English)

    María Paula, Houghton-Martínez; Jairo, Amaya-Guío; Luz Amparo, Díaz-Cruz.

    2012-03-01

    Full Text Available Objetivo: revisar el diagnóstico clínico, histológico e inmunohistoquímico; las alternativas terapéuticas y los factores que influyen en el pronóstico del melanoma amelanocítico de vagina. Materiales y métodos: se presenta el caso de una paciente de 49 años que consultó por masa vaginal de 8 cm en p [...] ared anterior de vagina, nacarada y con fondo necrótico a la Unidad de Patología Cervical y Colposcopia del Hospital de Engativá, institución de segundo nivel de complejidad que atiende pacientes de nivel socioeconómico bajo afiliados al régimen de seguridad pública. Se realizó resección amplia de la lesión. La patología quirúrgica informó melanoma fusocelular y epiteloide maligno. Se realizó una búsqueda sistemática usando las palabras clave: melanoma primario y vagina en las bases de datos Medline vía PubMed, Cochrane y Ebsco. Resultados: se encontraron 489 artículos de los cuales 31 estaban relacionados directamente con el tema, de estos se seleccionaron diez que correspondieron a nueve reportes de caso y a una revisión del tema. El diagnóstico clínico no es fácil. Las proteínas HMB45 y S100 son de gran utilidad en su identificación. La respuesta al tratamiento quirúrgico, la radioterapia y la quimioterapia es pobre. El pronóstico depende de la ploidía, la amelanosis y el índice mitótico. Conclusiones: el melanoma primario de vagina es una neoplasia rara y de mal pronóstico. Hace parte del grupo de melanomas de mucosa que tienen un origen y comportamiento biológico diferente al cutáneo. Tiene tendencia a la diseminación hematógena rápida y a recaídas locales. El tratamiento se basa en cirugía conservadora, radioterapia, quimioterapia y terapia biológica; sin embargo, su eficacia es limitada. Abstract in english Objective: reviewing clinical, histological and immunohistochemical diagnosis, therapeutic alternatives and factors influencing prognosis for amelanotic melanoma of the vagina. Materials and methods: this article presents the case of a 49yearold patient who consulted the Engativá Hospital’s Cervical [...] Pathology and Colposcopy Unit due to an 8 cm diameter necrotic pearlywhite vaginal mass on the anterior vaginal wall. The hospital is a secondary level complexity institution dealing with low socioeconomic level patients affiliated to the public (subsidized) social security (health) system. A broad resection was made of the lesion. Surgical pathology revealed epithelioid fusocellular malignant melanoma. A systematic literature search was made using the following key words: primary melanoma and vagina in Medline databases via Pub Med, Cochrane and Ebsco. Results: 31 of the 489 articles found were directly related to the topic; 10 new case reports and a review were selected. Clinical diagnosis is not easy; HMB45 and S100 proteins are extremely useful in identifying it.Response to surgical treatment, radiotherapy and chemotherapy is poor. Prognosis depends on ploidy, amelanosis and mitotic index. Conclusions: Primary melanoma of the vagina is a rare neoplasm and has a poor prognosis. It forms part of a group of mucosal melanoma having an origin and biological behavior different to that of cutaneous melanoma. It tends to have rapid hematogenous dissemination and local relapses. Treatment is based on conservative surgery, radiotherapy, chemotherapy and biological therapy; however, its effectiveness is limited.

  7. Clinical evaluation of the effectiveness of radiotherapy for cervical carcinoma disseminated to the vagina

    International Nuclear Information System (INIS)

    The study presents an analysis of the data on 137 patients with cervical carcinoma metastases to the vagina (CCMV) treated with both combined (distance + contact) radiation and contact radiation alone administered in low, medium and high dose. It is shown that there was no correlation between radiotherapy efficacy and regimen (surgery, combined therapy or radiation) in the management of primary cervical carcinoma

  8. Optimization of vagina tumors brachytherapy by the usage of multichannel vaginal applicator

    International Nuclear Information System (INIS)

    Data about treatment of 46 patients with primary and metastatic cancer of vagina were represented in article. It was shown that multichannel vaginal applicator has much more benefits then single-channel one in combination with radiation therapy of vaginal tumors

  9. Congenital abnormality of the vagina complicated by haemato-pyocolpos in a 1-year labrador retriever.

    Science.gov (United States)

    Alonge, S; Romussi, S; Grieco, V; Luvoni, G C

    2015-06-01

    A 1-year-old female Labrador retriever was referred with a few days history of haematic-like vulvar discharge. Physical examination, vaginal inspection and palpation did not reveal any remarkable finding. Transabdominal ultrasound showed echogenic fluid accumulation in the vagina suggesting haemato-pyocolpos. An exploratory laparotomy was performed: a well-delimited ectasic vagina was identified. Ovariohysterectomy and partial vaginectomy and vaginoplasty were performed to spay the bitch and to remove the ectasic vagina. Post-operative recovery and 12-month follow-up were uneventful. Clinical, morphological and histological findings were consistent with a congenital abnormality of the muscular layer of the vagina complicated by haemato-pyocolpos. The disorganization of the vaginal tunica muscularis may have acted as locus minoris resistentiae in the vaginal wall. The organ was dilated and atonic due to the gradual accumulation of physiological fluids complicated by an overgrowth of genital bacteria. This congenital disorder has to be taken into account as differential diagnosis of haemato-pyocolpos with vaginal discharge in young bitches. PMID:25661902

  10. Long-term results of radiotherapy in primary carcinoma of the vagina

    International Nuclear Information System (INIS)

    Background: The long-term results of radiotherapy in primary carcinoma of the vagina are not well defined. Patients and Methods: The treatment results of 41 patients with primary malignancies of the vagina were analyzed. The mean follow-up period was 77.3 months (2.3-404 months). The predominant histology was squamous cell carcinoma, FIGO stages I: n = 7 (17.1%), II: n = 13 (31.7%), III: n = 13 (31.7%), and IVa: n = 8 (19.5%). Radiotherapy was the primary treatment for all patients. None of the patients had undergone prior surgery for vaginal carcinoma. The majority of patients received pelvic irradiation, including treatment of the inguinal lymphatics (median dose: 50 Gy). 26 patients received additional intravaginal brachytherapy. Results: Overall, 21 patients (51.2%) achieved complete remission, 17 patients (41.5%) had partial responses, and three patients (7.3%) had no change or progressive disease. The total median survival of the analyzed patients was 41.3 months. The 1-year survival probability was 85.4%, the 5-year survival probability 40.6%, and the 10-year survival probability 27.2%. Univariate analysis revealed a survival advantage for earlier tumor stages (FIGO I and II) compared to advanced stages (FIGO III and IV), with a median survival of 58.1 months compared to 26.8 months. Treatment side effects were tolerable and easily managed. Conclusion: Definite radiotherapy is the treatment of choice for primary carcinomas of the vagina. Considering that primarmas of the vagina. Considering that primary malignancies of the vagina are typically diseases of the elderly, it should be noted that radiotherapy is especially well tolerated in this population. (orig.)

  11. Mioepitelioma de vagina: neoplasia poco frecuente en esta localización, reporte de un caso

    Scientific Electronic Library Online (English)

    Alfredo, Romero R; Mario, Melo U; Paula, Barajas S; Juvenal, Baena A; Luz Mery, Vargas L.

    Full Text Available Antecedentes: Los mioepiteliomas, son tumores poco frecuentes originados a partir de la proliferación de células mioepiteliales. La mayor parte localizados en las extremidades inferiores y en glándulas salivales. Existen ocasionales informes previos de MEP que involucren la vagina. Objetivo: Describ [...] ir un caso de mioepitelioma localizado en vagina. Caso clínico: Embarazada de 29 años edad, quien presenta una masa vaginal de un año de evolución, localizada en el himen. El examen histopatológico muestra una lesión compuesta por células fusiformes con positividad inmunohistoquímica para vimentina, citoqueratinas (CK) AE1/ AE3, S100, CD10, receptores de estrógenos y progesterona, Bcl2 y calponina y negatividad para desmina, actina muscular especifica, actina de músculo liso y p63. Con los anteriores hallazgos se interpreta la lesión como un mioepitelioma primario vaginal. Conclusión: Los mioepiteliomas son tumores que requieren para su diagnostico, análisis con técnicas de inmunohistoquímica o ultraestructurales que permitan diferenciarlos de otros tumores. Abstract in english Background: The myoepitheliomas are rare tumors arising from the proliferation of myoepithelial cells. Most tumors are located in the lower extremity and salivary glands. There have been only occasional myoepithelial neoplasms previously reported involving the vagina. Objective: Describe a case of m [...] yoepithelioma located in the vagina of a pregnant woman. Case report: A 29 years old pregnant female, who about 1 year prior has a vaginal mass, located in the hymen. At histopathological examination shows a mass composed of spindle cells with positivity immunohistochemical studies for vimentin, cytokeratin AE1/AE3, S100, CD10 and calponin and negative for desmin, actinmuscle specific (HHF35), smooth muscle actin and p63. With these findings it was established the diagnosis of myoepithelioma in the vagina. Conclusion: Myoepitheliomas are tumors requiring for diagnostic of immunohistochemistry or ultrastructural techniques that allow its differentiation from other tumors.

  12. Mioepitelioma de vagina: neoplasia poco frecuente en esta localización, reporte de un caso

    Directory of Open Access Journals (Sweden)

    Alfredo Romero R

    2012-01-01

    Full Text Available Antecedentes: Los mioepiteliomas, son tumores poco frecuentes originados a partir de la proliferación de células mioepiteliales. La mayor parte localizados en las extremidades inferiores y en glándulas salivales. Existen ocasionales informes previos de MEP que involucren la vagina. Objetivo: Describir un caso de mioepitelioma localizado en vagina. Caso clínico: Embarazada de 29 años edad, quien presenta una masa vaginal de un año de evolución, localizada en el himen. El examen histopatológico muestra una lesión compuesta por células fusiformes con positividad inmunohistoquímica para vimentina, citoqueratinas (CK AE1/ AE3, S100, CD10, receptores de estrógenos y progesterona, Bcl2 y calponina y negatividad para desmina, actina muscular especifica, actina de músculo liso y p63. Con los anteriores hallazgos se interpreta la lesión como un mioepitelioma primario vaginal. Conclusión: Los mioepiteliomas son tumores que requieren para su diagnostico, análisis con técnicas de inmunohistoquímica o ultraestructurales que permitan diferenciarlos de otros tumores.Background: The myoepitheliomas are rare tumors arising from the proliferation of myoepithelial cells. Most tumors are located in the lower extremity and salivary glands. There have been only occasional myoepithelial neoplasms previously reported involving the vagina. Objective: Describe a case of myoepithelioma located in the vagina of a pregnant woman. Case report: A 29 years old pregnant female, who about 1 year prior has a vaginal mass, located in the hymen. At histopathological examination shows a mass composed of spindle cells with positivity immunohistochemical studies for vimentin, cytokeratin AE1/AE3, S100, CD10 and calponin and negative for desmin, actinmuscle specific (HHF35, smooth muscle actin and p63. With these findings it was established the diagnosis of myoepithelioma in the vagina. Conclusion: Myoepitheliomas are tumors requiring for diagnostic of immunohistochemistry or ultrastructural techniques that allow its differentiation from other tumors.

  13. Morphological Studies on the Vagina and Vestibule of Dromedary Camels (Camelus dromedarius) / Estudios Morfológicos de la Vagina y Vestíbulo del Camello (Camelus dromedarius)

    Scientific Electronic Library Online (English)

    Ahmed, Sayed-Ahmed; Anwer, Elshafey; Ahmed, Abd-Elmaksoud.

    1156-11-01

    Full Text Available El camello (Camelus dromedarius) es una importante especie de ganado de usos múltiples y el consumo de su carne corresponde al 10% aproximadamente del consumo de carne roja en Egipto. La eficiencia reproductiva del camello, bajo condiciones naturales, se considera generalmente baja. El conocimiento [...] adecuado sobre los órganos genitales tubulares de esta especie podría facilitar la aplicación de una nueva metodología de reproducción. Por lo tanto, se llevó a cabo este estudio para investigar la morfología de la superficie de la mucosa de la vagina y el vestíbulo en camellos, utilizando luz, escaneado y microscopía electrónica de transmisión. La superficie de la mucosa de la vagina está formado por epitelio columnar estratificado con células secretoras mucosas (células en copa). La microscopía electrónica de barrido (SEM) de la vagina reveló la presencia de pliegues primarios y secundarios longitudinales y pequeños pliegues transversales. El epitelio columnar mostró un límite celular marcado y su superficie apical se evidenció salpicado por una gran cantidad de microvellosidades. La microscopía electrónica por transmisión (TEM) confirmó la presencia de microvellosidades en las superficies apicales y mostró algunos gránulos secretores en la región supranuclear del epitelio columnar. El vestíbulo del dromedario está revestido por epitelio estratificado queratinizado, de tipo escamoso. La lámina basal y el estrato granuloso de este epitelio mostraron una fuerte reacción PAS positiva. La microscopía electrónica de barrido (SEM) del vestíbulo reveló la presencia de pequeños pliegues transversales longitudinales y finos, con gran cantidad de restos de mucosidad. Sin embargo, la microscopía electrónica por transmisión (TEM) del vestíbuloreveló un epitelio queratinizado escamoso estratificado, con una capa basal de células cúbicas y capas superficiales de células escamosas. Abstract in english The camel (Camelus dromedarius) is an important multipurpose livestock species and its meat represents about 10% of the red meat consumption in Egypt. The reproductive efficiency of camel under natural condition is generally considered to be low. Sound knowledge about the tubular genital organs of t [...] his species might facilitate the application of new reproductive methodology. Our study was therefore conducted to investigate the morphology of mucosal surface of vagina and vestibule on camels using light, scanning and transmission electron microscopy. The mucosal surface of vagina consisted of stratified columnar epithelium with mucous secreting cells (goblet-like cells). SEM of vagina revealed the presence of longitudinal primary and secondary folds and small transverse folds. The columnar epithelium showed marked cell boundary and its apical surface was studded by a lot of microvilli. TEM confirmed the presence of microvilli at apical surfaces and showed some secretory granules in the supranuclear region of the columnar epithelium. The vestibule of dromedary camel was lined by stratified squamous keratinized epithelium. Basal lamina and stratum granulosum of this epithelium showed strong PAS positive reaction. SEM of vestibule revealed the presence of small longitudinal and fine transverse folds with a lot of mucous debris. However TEM of vestibule showed the stratified squamous keratinized epithelium with basal layer of cuboidal cells and superficial layers of squamous cells.

  14. Primary carcinoma of the vagina: A study of a Radiumhemmet series of 145 cases

    International Nuclear Information System (INIS)

    The infrequency of carcinoma of the vagina and the concomitant paucity of cases treated at any one institution have long delayed an appreciation of the fundamental characteristics of this disease and hindered the development of an effective programme of management. In the past decade publications based on relatively large number of cases have appeared from several clinics. These have greatly augmented previous reports of this disorder. However, the lack of a uniform clinical classification regarding the extent of the disease process before treatment has invalidated any attempt to compare the efficacy of methods of therapy employed at different clinics. It is the purpose of this paper to suggest a clinical classification for carcinoma of the vagina and to evaluate the cases treated at the Radiumhemmet in accordance with this proposed staging

  15. Entrenamiento de carneros para recolección de semen mediante vagina artificial, utilizando como estímulo objetos inanimados

    OpenAIRE

    Virginio Aguirre Flores; Reyes V\\u00E1zquez Rosales; Agust\\u00EDn Orihuela Trujillo

    2005-01-01

    Con el fi n de desarrollar una metodología para entrenar carneros en la recolección de semen con vagina artifi cial (VA), montando un objeto inanimado, se utilizaron nueve animales que se sometieron a cuatro etapas de preparación. La primera con el propósito de lograr la manifestación del repertorio sexual natural, y el resto para llevar a cabo un programa de condicionamiento operante: cuando la respuesta correcta (monta) sucedía, en un inicio provocada por un estado de m...

  16. Difference in signalling between various hormone therapies in endometrium, myometrium and upper part of the vagina

    OpenAIRE

    Hanifi-moghaddam, P.; Boers-sijmons, B.; Klaassens, A. H. A.; Wijk, F. H.; Ijcken, W. F. J.; Spek, P. J.; Verheul, H. A. M.; Kloosterboer, H. J.; Burger, C. W.; Blok, L. J.

    2008-01-01

    BACKGROUND: Combined hormone treatments in post-menopausal women have different clinical responses on uterus and vagina; therefore, we investigated differences in steroid signalling between various hormone therapies in these tissues. METHODS: A total of 30 post-menopausal women scheduled for hysterectomy were distributed into four subgroups: control-group (n = 9), Tibolone-group (n = 8); estradiol (E(2))-group (n = 7); E(2) + medroxyprogesterone acetate (MPA)-group (n = 6). Medication was adm...

  17. Recurrent Fistula between Ileal Pouch and Vagina—Successful Treatment with a Gracilis Muscle Flap

    OpenAIRE

    Wolfram Trudo Knoefel; Stefan Benedikt Hosch; Claus Ferdinand Eisenberger; Alexander Rehders; Andreas Raffel; Feride Aydin

    2009-01-01

    Fistulae between an ileal pouch and the vagina are an uncommon complication of ileal pouch-anal anastomosis following proctocolectomy and mucosectomy in patients with familial adenomatous polyposis coli. Several reports describe the successful use of muscle flaps to close recurrent pouch-vaginal-fistulae (PVF). However, series only contain small numbers and an optimal management has not yet been determined. We report the case of a 26-year old woman with a third recurrence of a PVF after proct...

  18. Hematocolpos in double vagina associated with uterus didelphus: US and MR findings

    International Nuclear Information System (INIS)

    The malformative syndrome of double vagina in association with uterus didelphus and kidney agenesis is a rare condition, often asymptomatic: if this condition is accompanied by imperforated obstructed hemivagina, the clinical manifestations depend on the presence of hematocolpos. MRI plays an important role for diagnosis because it allows to characterize the nature of the lesion and to evaluate the anatomical details of the uterine malformation. The authors describe this complex genital malformation and discuss the main US and MRI features

  19. Verrucous carcinoma of the cervix and vagina treated by radiation therapy

    International Nuclear Information System (INIS)

    Seven cases of verrocous carcinoma of the uterine cervix (five) and vagina (two) were reviewed. Four of the five patients managed primarily with radiation therapy have survived a median of 10 years. Of the two patients managed primarily with surgery, one experienced recurrence and was then successfully treated with radiation therapy; the other died of metastatic carcinoma. No anaplastic transformation of lesions or distant metastases occurred in the patients treated with radiation therapy. Human papilloma virus was isolated in two patients

  20. Hematocolpos in double vagina associated with uterus didelphus: US and MR findings

    Energy Technology Data Exchange (ETDEWEB)

    Ballesio, L.; Andreoli, C.; De Cicco, M.L.; Angeli, M.L.; Manganaro, L

    2003-02-01

    The malformative syndrome of double vagina in association with uterus didelphus and kidney agenesis is a rare condition, often asymptomatic: if this condition is accompanied by imperforated obstructed hemivagina, the clinical manifestations depend on the presence of hematocolpos. MRI plays an important role for diagnosis because it allows to characterize the nature of the lesion and to evaluate the anatomical details of the uterine malformation. The authors describe this complex genital malformation and discuss the main US and MRI features.

  1. Long-term results of radiotherapy in primary carcinoma of the vagina

    Energy Technology Data Exchange (ETDEWEB)

    Hegemann, Stefan; Willich, Normann [University Hospital, Muenster (Germany). Dept. of Radiotherapy and Radiation Oncology; Schaefer, Ulrich [University Hospital, Muenster (Germany). Dept. of Radiotherapy and Radiation Oncology; Lippe Hospital, Lemgo (Germany). Dept. of Radiotherapy; Lelle, Ralph [University Hospital, Muenster (Germany). Dept. of Gynecology and Gynecologic Oncology; Micke, Oliver [University Hospital, Muenster (Germany). Dept. of Radiotherapy and Radiation Oncology; Franziskus Hospital, Bielefeld (Germany). Dept. of Radiotherapy and Radiation Oncology

    2009-03-15

    Background: The long-term results of radiotherapy in primary carcinoma of the vagina are not well defined. Patients and Methods: The treatment results of 41 patients with primary malignancies of the vagina were analyzed. The mean follow-up period was 77.3 months (2.3-404 months). The predominant histology was squamous cell carcinoma, FIGO stages I: n = 7 (17.1%), II: n = 13 (31.7%), III: n = 13 (31.7%), and IVa: n = 8 (19.5%). Radiotherapy was the primary treatment for all patients. None of the patients had undergone prior surgery for vaginal carcinoma. The majority of patients received pelvic irradiation, including treatment of the inguinal lymphatics (median dose: 50 Gy). 26 patients received additional intravaginal brachytherapy. Results: Overall, 21 patients (51.2%) achieved complete remission, 17 patients (41.5%) had partial responses, and three patients (7.3%) had no change or progressive disease. The total median survival of the analyzed patients was 41.3 months. The 1-year survival probability was 85.4%, the 5-year survival probability 40.6%, and the 10-year survival probability 27.2%. Univariate analysis revealed a survival advantage for earlier tumor stages (FIGO I and II) compared to advanced stages (FIGO III and IV), with a median survival of 58.1 months compared to 26.8 months. Treatment side effects were tolerable and easily managed. Conclusion: Definite radiotherapy is the treatment of choice for primary carcinomas of the vagina. Considering that primary malignancies of the vagina are typically diseases of the elderly, it should be noted that radiotherapy is especially well tolerated in this population. (orig.)

  2. CT and MR imaging findings of primary leiomyosarcoma of the vagina : a case report

    Energy Technology Data Exchange (ETDEWEB)

    Cho, So Hee; Rha, Sung Eun; Cho, Song Mee; Byun, Jae Young [College of Medicine, The Catholic Univ. of Korea, Seoul (Korea, Republic of)

    2001-09-01

    Primary malignant lesions of the vagina are uncommon and represent approximately 1-2% of all gynecologic malignancies. About 2% of all malignant vaginal lesions are primary sarcomas, the most common of these being leiomyosarcoma. We report the CT and MR imaging findings in a 41-year-old woman with vaginal leiomyosarcoma presenting as a bulky solid mass which caused expansion of the vaginal canal.

  3. A simple, inexpensive applicator for irradiation of localized areas of the vagina with intracavitary brachytherapy

    International Nuclear Information System (INIS)

    Purpose: To describe the construction of a simple, inexpensive applicator for irradiation of localized areas of the vagina with intracavitary brachytherapy Methods and Materials: It was desirable to avoid an interstitial implant in an elderly patient with a stage T2 vaginal cancer. The final phase of radiation therapy was delivered with a custom made intracavitary cylinder that allowed the high-dose area to be limited to the portion of the vagina at high risk for residual disease. The applicator was fabricated from a clear cast acrylic (Lucite) rod with dimensions 3.5 cm diameter x 5.0 cm long. The applicator contained 11 parallel grooves, each 1.8 mm deep x 2.2 mm wide, machined along the surface of the cylinder parallel its long axis at 1.0 cm increments. Plastic needles (15 gauge) were inserted into the grooves along the surface of the acrylic cylinder and held in place with heat shrink tubing. The applicator was easily inserted and positioned without anesthesia. Standard low dose rate 192Ir ribbons were inserted into the plastic needles after positioning the applicator in the vagina. Results: Construction of this applicator system requires a few weeks notice and approximately $150. Fabrication of the grooved cylinder is a routine task for a workshop with a milling machine. A step-by-step description of how to construct and use the applicator is provided along with the telephone numbers of commercial vendors to call to order all necessary materials. Concall to order all necessary materials. Conclusion: This article describes a simple, inexpensive method for constructing a customized vaginal applicator that can be used to treat a limited area of the vagina with intracavitary brachytherapy

  4. Survival of gram positive anaerobic cocci on swabs and their isolation from the mouth and vagina.

    OpenAIRE

    Smith, G. L.; Cumming, C. G.; Ross, P. W.

    1986-01-01

    The survival of Gram positive anaerobic cocci on plain cotton wool and albumin coated swabs held in various transport media was investigated. Results suggested that in most cases Amies', Stuart's and VMGII media do not offer any more protection to the bacteria than storing swabs dry in their containers. A technique was developed for the isolation and identification of Gram positive anaerobic cocci from the mouth and vagina, incorporating bicozamycin in the medium as a selective agent. Few str...

  5. Measuring the space between vagina and rectum as it relates to rectocele

    OpenAIRE

    Jin Liu, Li-dong Zhai

    2009-01-01

    AIM: To measure the normal space between the posterior wall of the vagina and the anterior wall of the respectively rectum using computed tomography (CT) and reveal its were relationship to rectocele.METHODS: A total of twenty female volunteers without rectocele were examined by CT scan. We performed a middle level continuous horizontal pelvic scan from the upper part to the lower part and collected the measurement data to analyze the results using t-test.RESULTS: Twenty volunteers were enrol...

  6. Foreign body in vagina: a cause of persistent vaginal discharge in children

    OpenAIRE

    Pallavee, P.; Sunita Samal; Sabita, P.

    2013-01-01

    Vulvovaginitis and vaginal discharge in pediatric patients, while not uncommon, is commonly believed to be due to such causes as absence of the protective effect on the vaginal mucosa. However, other causes need also to be kept in mind. We report a case of chronic vaginal discharge in a 5 yr old, who had retained a foreign body in her vagina for 6-7 months. [Int J Reprod Contracept Obstet Gynecol 2013; 2(2.000): 224-225

  7. CT and MR imaging findings of primary leiomyosarcoma of the vagina : a case report

    International Nuclear Information System (INIS)

    Primary malignant lesions of the vagina are uncommon and represent approximately 1-2% of all gynecologic malignancies. About 2% of all malignant vaginal lesions are primary sarcomas, the most common of these being leiomyosarcoma. We report the CT and MR imaging findings in a 41-year-old woman with vaginal leiomyosarcoma presenting as a bulky solid mass which caused expansion of the vaginal canal

  8. Effect of prolonged use of high dose of tibolone on the vagina of ovariectomized rats.

    Science.gov (United States)

    Henriques, Helene Nara; de Carvalho, Ana Carolina Bergmann; Soares Filho, Porphirio José; Pantaleão, José Augusto Soares; Guzmán-Silva, Maria Angélica

    2011-08-01

    The aim of this study was evaluate the effect of prolonged use of high dose of tibolone on the vagina of ovariectomized rats. Bilateral ovariectomy was performed on 14 rats weighing 250 g. Thirty days later, vaginal smears were collected verifying the menopause status by anoestrus cytology. Rats were divided randomly into groups: experimental rats (n = 9) received 1 mg tibolone/day orally and control rats (n = 6) received placebo (carboxymethylcellulose). After 150 days, all rats were sedated and euthanized by cervical displacement. The vagina was removed, fixed in 10% buffered formalin, sampled and processed for paraffin embedding. Histological sections were stained with haematoxylin and eosin, picrosirius red, periodic acid Schiff (PAS) and PAS-diastase, and Weigert's resorcin-fuchsin. Cell proliferation was analysed by immunohistochemistry to detect Ki67. Histomorphometric analyses were performed for epithelial thickness, per cent area of collagen fibres and blood vessels, mast cells and Ki67-positive nuclei per mm of basal membrane. Means and standard error of means were calculated, and data were compared using the Mann-Whitney test, with significance level at P tibolone group when compared with the control group. Furthermore, the content of glycogen and glycoproteins in the vaginal epithelium was modified by tibolone. Tibolone administered in high dose and for a long period has a trophic effect, reversing vaginal atrophy, and has no dysplastic or neoplastic effect in the vagina of ovariectomized rats. PMID:21518049

  9. Potential proton beam therapy for recurrent endometrial cancer in the vagina.

    Science.gov (United States)

    Yanazume, Shintaro; Arimura, Takeshi; Kobayashi, Hiroaki; Douchi, Tsutomu

    2015-05-01

    Proton beam radiotherapy mainly has been used in the gynecological field in patients with cervical cancer. The efficacy of proton beam therapy in patients with recurrent endometrial cancer has not yet been determined. A 77-year-old endometrial cancer patient presented with recurrence in the vagina without distant metastasis following hysterectomy. A hard mass measuring 6?cm originated from the apex of the vagina, surrounded the vaginal cavity, and infiltrated the proximal and distal vagina. The patient received proton beam radiotherapy using a less invasive particle treatment system while minimizing the dose to the surrounding normal tissues. The dose to the planning target volume was 74?Gy (relative biological effectiveness) with 37 fractions. The patient was treated with 150-210-MeV proton beams for 53?days. Proton beam therapy led to the disappearance of tumors without any complications except for grade 1 cystitis although evidence of further complications is not available past our 6-month follow-up period. Proton beam therapy may become a useful treatment modality for recurrent endometrial cancer as well as cervical uterine cancer. PMID:25369803

  10. The social vagina: labia elongation and social capital among women in Rwanda.

    Science.gov (United States)

    Larsen, Josefine

    2010-10-01

    Far from being an individual concern, vaginas are located within complex socio-cultural settings. The acceptability of policies that focus on health-promoting behavioural change is influenced by values regarding normative gender and sexual roles. In Rwanda, the elongation of the labia minora through manual manipulation is not an individual act but takes place in social groups and thus cannot be fully understood by focusing one's attention solely on the individual-related behavioural components but, rather, on the social environment in which it exists. This paper aims to increase knowledge about labia elongation and assesses whether this vaginal practice produce social capital. PMID:20665297

  11. Fungicidal Activity of Fluconazole against Candida albicans in a Synthetic Vagina-Simulative Medium

    OpenAIRE

    Moosa, Mahomed-Yunus S.; Sobel, Jack D.; Elhalis, Hussain; Du, Wenjin; Akins, Robert A.

    2004-01-01

    Fluconazole (FLZ) has emerged as a highly successful agent in the management of systemic infections of Candida. Cure rates for symptomatic candidiasis following single 150-mg FLZ dose therapy exceed 90%. In vitro, however, FLZ is fungistatic only in a narrow pH range and is not effective at vaginal pH, 4.2. This study evaluated the effect of FLZ on Candida albicans under in vitro conditions resembling the vaginal microenvironment, using vagina-simulative medium (VS). We found that FLZ was fun...

  12. Devices for interstitial radiotherapy of recurrents and metastases of uterine cancer to the vagina

    International Nuclear Information System (INIS)

    Three types of devices for interstitial radiotherapy have been developed in accordance with the technique of successive manual introduction of intrastates and radioactive sources taking into account localization, size, and degree of infiltration of underlaid tissues of recurrent and metastatic tumors during uterine cancer in all vagina sections. The proposed fixing devices provide safe predetermined source position and allow one to conduct local irradiation of pathological focus with minimum radiation loading on adjacensst organs and tiues, simplify dosimetric calculations of absorbed doses and reduce time of manipulation with radioactive sources

  13. The relative efficacy of HDR and LDR interstitial brachytherapy in squamous cell carcinoma of vagina

    International Nuclear Information System (INIS)

    Introduction: Beginning in 1982 we performed low dose rate (LDR) interstitial template brachytherapy (ISTB) for carcinoma of the vagina. High dose rate (HDR) remote afterloading has been used exclusively since 1991. We compare the results LDR and HDR brachytherapy. Material and Methods: Between 1982 and 1994, 30 patients with primary squamous cell carcinoma of vagina received external beam radiotherapy (EBRT) and brachytherapy. The AJCC stage distribution was 3 stage I, 25 stage II, and 2 stage III. The average central pelvic EBRT dose was 35 Gy. Pelvic side wall EBRT doses ranged from 45 to 50.4 Gy. Nineteen patients had LDR treatment; 3 intracavitary brachytherapy (ICB) and 16 ISTB. Eleven patients had HDR treatment; 2 ICB and 9 ISB. The average dose delivered by LDR was 41.2 Gy usually in 2 fractions, and by HDR 32.5 Gy in 6 fractions of 500-550 cGy. Local failures were confirmed pathologically. The absolute survival (AS) and relapse-free survival (RFS) were calculated using Kaplan-Meier method and compared with logrank statistics. Results: The mean follow-up was 77 months for LDR and 23 months for HDR. Local and regional control was achieved in 90% (27/30) of the patients. Three year AS was 84% and RFS was 87%. There was no significant difference between LDR and HDR in AS, RFS or local-regional control, (log rank p=0.85, p=0.12 and p=0.35 respectively). The single HDR local failure presented in a patient with extensive stage II disease who declined ISTB. There werge II disease who declined ISTB. There were fewer complications following HDR. The 1 case of extensive vaginal necrosis and the 3 cases of rectovaginal fistula that required surgery occurred only with LDR brachytherapy. Discussion: Excellent local and regional control of carcinoma of the vagina can be achieved by administering limited doses of external radiation and brachytherapy. Interstitial template implants are the best means of encompassing paravaginal disease while sparing the adjacent uninvolved normal tissues from high doses of radiation. HDR technology is an effective means of administering high uniform tumor doses, maximizes dose control to the bladder and rectum and improves radiation safety. Conclusion: Optimal tumor control and less morbidity at 2 years after treatment can be achieved with HDR-ISTB in squamous carcinoma of the vagina compared to alternative treatments

  14. Pre leukemic granulocytic sarcoma of vagina: a case report with review of literature

    International Nuclear Information System (INIS)

    Granulocytic sarcoma is an extramedullary tumor of malignant granulocytic progenitor cells, that may precede the onset of acute myeloid leukemia or appear during the leukemic manifestation or blastic crisis of chronic myeloproliferative disorders. A case of granulocytic sarcoma of vagina in a 27 year old woman treated with local radiotherapy is described. After seven months of follow up she developed acute myeloid leukemia. The case has been presented in view of its rarity and discussed in light of the available literature. (author). 13 refs., 1 fig

  15. Congenital malformation of the vaginal orifice, imperforate vagina, in the common marmoset (Callithrix jacchus).

    Science.gov (United States)

    Niimi, Kimie; Oguchi, Ayaka; Nishio, Kenji; Okano, Yasushi; Takahashi, Eiki

    2015-04-01

    The following is a report on a congenital vaginal malformation, imperforate vagina, in the common marmoset (Callithrix jacchus). This anomaly was observed for the first time in an adult female in our research colony. There was no uterine and vaginal aplasia or atresia in her grossly normal genital tract. The plasma progesterone concentration suggested that the ovarian cycle had ceased. However, this may not be related to a functional anomaly, but rather to suppressed ovulation resulting from subordination to cagemates considering the various stages of follicular development observed. PMID:25391536

  16. Sperm-storage tubules in the vagina of the ostrich (Struthio camelus)

    OpenAIRE

    Bezuidenhout, A. J.; Soley, John Thomson; Groenewald, Hermanus B.; Burger, W. P.

    1995-01-01

    Sperm-storage tubules have been described in a number of species of birds. The presence of these tubules in the Rhea has been mentioned, but no description of these structures in ratites is available. The purpose of this study was to determine the presence and morphology of sperm-storage tubules in the vagina of the ostrich. The study was performed with the use of conventional light- and electron-microscopic techniques. Sperm-storage tubules were located in a 200-mm-wide band of t...

  17. Role of radiation therapy in the management of primary carcinoma of the vagina

    International Nuclear Information System (INIS)

    A retrospective analysis of 88 patients with microscopically proven primary carcinoma of the vagina is presented. All patients were treated between 1957 and 1975 and have been followed for a minimum of 5 years. The technique of treatment, external, intracavitary and interstitial irradiation has been highly integrated and individualized. Several important features could be drawn from the current data: (1) The necessity for individualized radiation treatment to achieve the success, (2) the necessity to subdivide stage II into II A and II B is clearly shown by the 5-year survival data, (3) a relatively low complication rate from the use of high dose combined radiation modalities in higher stages is demonstrated. (Auth.)

  18. Melanosis of the vagina and human papillomavirus infection, an uncommon pathology: Case Report / Melanosis de la vagina e infección por virus del papiloma humano, una patología poco común: Reporte de un Caso

    Scientific Electronic Library Online (English)

    José, Núñez-Troconis; Mariela, Delgado; Gerardo, González; Airiaudis, Rivas; Katherine, Molero.

    2011-09-01

    Full Text Available Las lesiones melanóticas de la vagina son infrecuentes. y Solo pocos casos han sido reportados. Se presenta el caso de una mujer de 34 años quien es referida con diagnóstico de una Neoplasia Intraepitelial Vaginal 1. Al examen ginecológico, se encontraron dos áreas hiperpigmentadas en la vagina. La [...] exploración colposcópica del cuello uterino y vagina reveló la presencia de una lesión aceto-blanca en la pared lateral derecha del tercio superior de la vagina. Muestras de biopsias fueron tomadas en dichas áreas. El estudio histológico reportó una melanosis de la vagina y una infección por el virus del Papiloma Humano (VPH). Se realizó un panel de estudio inmunohistoquímico de marcadores epiteliales en las muestras vaginales: tales como citoqueratina AE1/AE3 y antígeno epitelial de membrana; marcador mesenquimal: vimentin; marcadores melanóticos: proteina S-100 y HMB45 (Human Melanoma Black); marcadores de proliferación celular: antígeno de proliferación nuclear (PCNA), y la oncoproteína P-53. Se realizó Hibridización In Situ para establecer los tipos de alto (16, 18, 31, 45) y bajo (6, 11) riesgo de VPH en las muestras vaginales. Los marcadores CK, EMA y Vimentin fueron 2+. Los marcadores melanótico, el HMB45 y el S100, y el PCNA fueron 1+ en la capa basal. P-53 fue negativo. El tejido melanótico y la lesión acetoblanca fueron positivos al VPH 6,11. En conclusión, la melanosis vaginal es una patología poco frecuente. Usualmente, se ha reportado en mujeres mayores de 40 años. Presentamos un caso de una melanosis de la vagina infectada con un tipo de VPH de bajo riesgo en una mujer joven y una revisión de la literatura. Abstract in english Benign melanotic lesions of the vagina are uncommon and only a few cases have been reported in the literature. A 34-year-old woman was referred because of a Vaginal Intraepithelial Neoplasia 1 biopsy result. On the gynecological examination, two different hyperpigmented areas were noted in the vagin [...] a. The colposcopic visualization of the cervix and vagina found an aceto-white lesion at the right lateral wall of the upper third of the vagina. Biopsies from three areas were taken. Histological study reported a melanosis of the vagina and HPV infection. An immunohistochemical panel of epithelial markers was performed in vaginal samples, such as Cytokeratin AE1/AE3 and epithelial membrane antigen, mesenchymal marker: vimentin; melanocytic makers: protein S-100 and HMB45 (Human Melanoma Black); proliferating cell marker: proliferating cell nuclear antigen (PCNA), and P-53 oncoprotein. High Risk (16, 18, 31, 45) and Low Risk (6, 11) HPV types were studied by In Situ Hybridization using the same vaginal samples. CK, EMA and Vimentin were 2+. Melanocytic markers, HMB45 and S100, and PCNA were 1+ in basal cell layer. P-53 was negative. The melanotic tissue and acetowhite lesion were positives to HPV Types 6,11. In conclusion, melanosis of the vagina is a uncommon benign pathology. Usually, melanosis is present in women over 40 years old. We present a case of melanosis of the vagina in a young woman infected with low-risk HPV types and review the literature.

  19. Postirradiation squamous cell carcinoma in situ of the vagina: treatment by topical 20 percent 5-fluorouracil cream

    International Nuclear Information System (INIS)

    Eight patients with squamous cell carcinoma in situ of the vagina were treated with monthly 5 day courses of 20% 5-fluorouracil cream applied to the vagina. Seven (87.5%) of the women had an initial complete response; however, three subsequently developed recurrence after the treatment was stopped. They were retreated, and two of these three patients achieved a subsequent complete response. The overall response to therapy was 75% (6/8) with the six women off therapy from 1.1 to 6.9 years. Total follow-up of all patients was 3.1 to 6.9 years with no patients having developed invasive carcinoma. Because of the high success rate with no associated serious sequelae, this is believed to be a satisfactory method of therapy for women with squamous cell carcinoma in situ of the vagina occurring after pelvic irradiation

  20. A longitudinal study of Staphylococcus hyicus colonization of vagina of gilts and transmission to piglets

    DEFF Research Database (Denmark)

    Wegener, Henrik Caspar; Skov Jensen, E.W.

    1992-01-01

    High Staphylococcus hyicus colonization rates were found in vaginal samples of healthy breeding sows and in skin samples of their offspring. Twenty-two different phage types were identified among the 720 isolates of S. hyicus examined. Two to 13 different phage types were isolated per herd. Phage typing, as well as characterization of about 10 % of the isolates by plasmid profiles and antibiogram patterns, showed that, several different clones of S. hyicus could be present simultaneously in vagina of gilts and also on skin of piglets. Generally isolates from the vagina of one animal were identical as regards to phage types, plasmid profiles, and antibiogram patterns during the entire investigation period. Isolates from the skin of piglets were of the same type as their mothers, indicating that vertical transmission had taken place. S. hyicus strains isolated from the skin of piglets within 24 h after birth were identical to strains isolated 3 weeks after birth from the same litter, indicating that the vaginalstrains became part of a stable skin flora.

  1. Migration of a particulate radioactive tracer from the vagina to the peritoneal cavity and ovaries

    International Nuclear Information System (INIS)

    In this report we describe a radionuclide procedure designed to evaluate the migration of a particulate radioactive tracer from the vagina to the peritoneal cavity and ovaries, as well as the determination of the patency of the pathways between these two extremes of the female reproductive system. Technetium-99m-labelled human albumin microspheres (technetium-99m-HAM) were deposited in the posterior fornices of 24 patients a day before they were to undergo different gynaecological operations. During this period sequential images were obtained and after the operation radioactivity levels in the removed organs and tissues were counted with a scintillation detector. In 14 out of 21 cases, the ovaries and fallopian tubes were counted separately from the uterus. Nine were positive (radioactivity levels were sufficiently high in the tubes and ovaries) and 5 were negative (no substantial radioactivity levels could be detected in either the tubes or the ovaries). The 5 negative results all occurred in patients with proved tubal damage as a result of previous infection. All the results were either true positive or true negative, providing evidence of migration, or obstruction, of technetium-99m-HAM from the vagina through the uterus and tubes to the peritoneal cavity and ovaries

  2. Reconstruction of the anus, rectovaginal septum, and distal part of the vagina after postirradiation necrosis. Report of a unique case

    International Nuclear Information System (INIS)

    Successful repair of postirradiation total loss of the anal sphincters, rectovaginal septum, and distal part of the vagina is reported. Gracilis muscle flap was used as a substitute sphincter. Part of the muscle was wrapped-up in a split skin graft. To the authors' knowledge, this is the first report on new application of gracilis muscle and split skin graft in perineal reconstruction

  3. Absence of a vagina and right sided adnexa uteri in the Waardenburg syndrome: a possible clue to the embryological defect.

    OpenAIRE

    Goodman, R. M.; Oelsner, G.; Berkenstadt, M.; Admon, D.

    1988-01-01

    An 18 year old single Jewish woman with the Waardenburg syndrome and absence of a vagina and right sided adnexa uteri is reported. Other congenital malformations associated with the Waardenburg syndrome are mentioned and it is postulated that they may be the result of an altered invasion of neurones or altered neurones in certain organ systems early in embryogenesis.

  4. Integrated external and interstitial radiation therapy for primary carcinoma of the vagina

    International Nuclear Information System (INIS)

    Twenty-seven patients with the diagnosis of primary carcinoma of the vagina were treated by definitive radiotherapy. Twenty-three patients received a combination of external and interstitial iridium-192 implant irradiation and four patients received only interstitial irradiation. Twenty-one patients had squamous cell carcinoma and six had adenocarcinoma. All patients were staged according to the FIGO classification. More than 70% of patients had relatively advanced local disease and conventional intracavitary irradiation was unsuitable. Local tumor control was observed in 85% (23 of 27 patients), and 56% of the patients remain alive and free of disease for a median follow-up period of 50 months to a maximum follow-up period of 84 months. Fifteen percent of the patients suffered from treatment-related complications

  5. Radiation therapy for primary squamous cell carcinoma of the vagina: Stanford University experience

    International Nuclear Information System (INIS)

    A retrospective analysis of 38 patients with primary squamous cell carcinoma of the vagina seen at Stanford University Medical Center from 1958 to 1984 was undertaken. Patients were analyzed with regard to symptoms, stage, treatment techniques, survival, patterns of failure, and complications. Eighteen patients were classified as FIGO Stage I, 5 as Stage II, 10 as Stage III, and 5 as Stage IV. The 5-year disease-free survival was 94% in Stage I, 80% in Stage II, 50% in Stage III, and 0% in Stage IV. Five patients (13%) had eight major complications secondary to treatment. Only 2 of 23 patients with Stage I or Stage II disease developed a recurrence. There was a significant correlation between dose and response in patients treated with radiotherapy

  6. Experimental inoculation model of Walker 256 carcinoma into vagina and cervix uteri of female rats Modelo experimental de Tumor de Walker 256 em vagina e colo de útero de ratas

    Directory of Open Access Journals (Sweden)

    Nara Macedo Botelho Brito

    2007-12-01

    Full Text Available PURPOSE: To establish an inoculation model of Walker 256 carcinoma on cervix uteri and vagina of rats. METHODS: Fifteen female rats were used, and assigned to three groups each one with five rats: group A - rats with 4x10(6 cells of Walker 256 carcinoma without acid acetic inoculation; group B - rats with 2x10(6 cells of Walker 256 carcinoma with acid acetic inoculation and group C: rats with 4x10(6 cells of Walker 256 carcinoma with acid acetic inoculation. The day before tumor cells inoculation the rats from groups B and C were anaesthetized with diethylether and 0,3 ml of acetic acid was inoculated into their vaginas. Tumor cell inoculation into the vagina and cervix was done under general anesthesia with diethylether. Then a endocervical brush was used to scrape the vaginal wall and after that 0,3 ml of the liquid containing tumor cells was inoculated on the vagina and cervix. For the tumor analysis, animals were euthanized at day 12 following tumor cell implantation by an excessive inhalation of diethylether. Tumor was resected entirely and weighed and the tumors were then sectioned and counter stained with hematoxylin and eosin for histopathologic evaluation. It was also calculated the percentage of tumor equivalent to the body weight by the formula: P= tumor weight / body weight x 100. Data were analyzed by one-way analysis of variance - ANOVA. P values OBJETIVO: Estabelecer um modelo de inoculação de Tumor de Walker 256 em vagina e colo de útero de ratas. MÉTODOS: Foram utilizadas 15 ratas fêmeas, virgens, adultas, pesando entre 200-250g, distribuídas em três grupos de estudo com cinco animais cada: grupo A (GA: ratas com tumor de Walker 256 em concentração de 4x10(6 sem ácido acético; grupo B (GB: ratas com tumor de Walker 256 em concentração de 2x10(6 células com ácido acético; grupo C (GC: ratas com tumor de Walker 256 em concentração de 4x10(6 células com ácido acético. No dia anterior à inoculação do tumor, foi realizada a inoculação de 0,3 ml de ácido acético a 10% na vagina das ratas de GB e GC; no dia seguinte, tanto estas como as ratas do grupo GA foram anestesiadas, feita a escarificação da parede vaginal com uma escova de endocérvice e inoculado 0,3ml de tumor na concentração de 4x10(6 células nos grupos GA e GC e 2x10(6 células no grupo GB. Após 12 dias, foi realizada a eutanásia e removido o tumor em bloco com vagina e cornos uterinos para análise, sendo pesado e averiguado seu volume e calculado as relações entre o seu peso e o peso final da rata e o seu volume e o peso final da rata. Os dados foram colhidos e submetidos à análise estatística pelo método ANOVA (um critério. RESULTADOS: A pega em GB e GC foi 100% e em GA 20%. Não houve diferença estatística entre as médias obtidas entre GB e GC. CONCLUSÃO: De acordo com a metodologia utilizada, o modelo de tumor de Walker 256 na vagina apresenta pega de 100% quando associado a ácido acético e não há diferença de comportamento com a inoculação de 4x10(6ou 2x10(6 células.

  7. Experimental inoculation model of Walker 256 carcinoma into vagina and cervix uteri of female rats / Modelo experimental de Tumor de Walker 256 em vagina e colo de útero de ratas

    Scientific Electronic Library Online (English)

    Nara Macedo Botelho, Brito; Marcus Vinicius Henriques, Brito; Rita de Kássia Vidigal, Carvalho; Lia Tavares de Moura Brasil, Matos; Thiago Sousa, Veloso; Diego Matos de, Vasconcelos; Rosângela Baía, Brito.

    2007-12-01

    Full Text Available OBJETIVO: Estabelecer um modelo de inoculação de Tumor de Walker 256 em vagina e colo de útero de ratas. MÉTODOS: Foram utilizadas 15 ratas fêmeas, virgens, adultas, pesando entre 200-250g, distribuídas em três grupos de estudo com cinco animais cada: grupo A (GA): ratas com tumor de Walker 256 em c [...] oncentração de 4x10(6) sem ácido acético; grupo B (GB): ratas com tumor de Walker 256 em concentração de 2x10(6) células com ácido acético; grupo C (GC): ratas com tumor de Walker 256 em concentração de 4x10(6) células com ácido acético. No dia anterior à inoculação do tumor, foi realizada a inoculação de 0,3 ml de ácido acético a 10% na vagina das ratas de GB e GC; no dia seguinte, tanto estas como as ratas do grupo GA foram anestesiadas, feita a escarificação da parede vaginal com uma escova de endocérvice e inoculado 0,3ml de tumor na concentração de 4x10(6) células nos grupos GA e GC e 2x10(6) células no grupo GB. Após 12 dias, foi realizada a eutanásia e removido o tumor em bloco com vagina e cornos uterinos para análise, sendo pesado e averiguado seu volume e calculado as relações entre o seu peso e o peso final da rata e o seu volume e o peso final da rata. Os dados foram colhidos e submetidos à análise estatística pelo método ANOVA (um critério). RESULTADOS: A pega em GB e GC foi 100% e em GA 20%. Não houve diferença estatística entre as médias obtidas entre GB e GC. CONCLUSÃO: De acordo com a metodologia utilizada, o modelo de tumor de Walker 256 na vagina apresenta pega de 100% quando associado a ácido acético e não há diferença de comportamento com a inoculação de 4x10(6)ou 2x10(6) células. Abstract in english PURPOSE: To establish an inoculation model of Walker 256 carcinoma on cervix uteri and vagina of rats. METHODS: Fifteen female rats were used, and assigned to three groups each one with five rats: group A - rats with 4x10(6) cells of Walker 256 carcinoma without acid acetic inoculation; group B - ra [...] ts with 2x10(6) cells of Walker 256 carcinoma with acid acetic inoculation and group C: rats with 4x10(6) cells of Walker 256 carcinoma with acid acetic inoculation. The day before tumor cells inoculation the rats from groups B and C were anaesthetized with diethylether and 0,3 ml of acetic acid was inoculated into their vaginas. Tumor cell inoculation into the vagina and cervix was done under general anesthesia with diethylether. Then a endocervical brush was used to scrape the vaginal wall and after that 0,3 ml of the liquid containing tumor cells was inoculated on the vagina and cervix. For the tumor analysis, animals were euthanized at day 12 following tumor cell implantation by an excessive inhalation of diethylether. Tumor was resected entirely and weighed and the tumors were then sectioned and counter stained with hematoxylin and eosin for histopathologic evaluation. It was also calculated the percentage of tumor equivalent to the body weight by the formula: P= tumor weight / body weight x 100. Data were analyzed by one-way analysis of variance - ANOVA. P values

  8. La vagina dentada: una interpretación de la Estela 25 de Izapa y las guacamayas del juego de pelota de Copán / The dented vagina: an interpretation for Stela 25 of Izapa and ballcourt macaws of Copan

    Scientific Electronic Library Online (English)

    Oswaldo, Chinchilla Mazariegos.

    Full Text Available Las aves representadas en la Estela 25 de Izapa y el juego de pelota de Copán forman el punto de partida para un examen del tema mitológico de la vagina dentada en Mesoamérica, y sus expresiones en el arte y la narrativa. Un amplio conjunto de narraciones mitológicas recopiladas en México y Guatemal [...] a sirve como base para un examen de la historia de Siete Guacamayo en el Popol Vuh, la cual se interpreta como una variante de un mito ampliamente difundido, relacionado con el origen del Sol y la Luna. La identificación de asuntos comunes, entre ellos el de la vagina dentada, refuerza la relación entre el mito del Popol Vuh y las representaciones de Izapa y Copán. A la vez, revela detalles poco conocidos sobre el simbolismo sexual presente en los mitos cosmogónicos mesoamericanos. Abstract in english The birds represented at Stela 25 of Izapa and Copan ball court are the starting point for the analysis of the mythological topic focused on the vagina dentata in Ancient Mesoamerica, as well as their expressions on art and narrative. A large body of mythological narratives is used as a basis for th [...] e examination of the "Siete Guacamayo" story included in the Popol Vuh, which is interpreted as part of a widely extended myth related with the creation of the Sun and the Moon. The identification of common issues, as the vagina dentata topic, strengthens the links between the Popol Vuh myth and the Izapa and Copan representations. It also reveals less known details on the sexual symbolism included in the Mesoamerican cosmogonic myths.

  9. La vagina dentada: una interpretación de la Estela 25 de Izapa y las guacamayas del juego de pelota de Copán The dented vagina: an interpretation for Stela 25 of Izapa and ballcourt macaws of Copan

    Directory of Open Access Journals (Sweden)

    Oswaldo Chinchilla Mazariegos

    2010-01-01

    Full Text Available Las aves representadas en la Estela 25 de Izapa y el juego de pelota de Copán forman el punto de partida para un examen del tema mitológico de la vagina dentada en Mesoamérica, y sus expresiones en el arte y la narrativa. Un amplio conjunto de narraciones mitológicas recopiladas en México y Guatemala sirve como base para un examen de la historia de Siete Guacamayo en el Popol Vuh, la cual se interpreta como una variante de un mito ampliamente difundido, relacionado con el origen del Sol y la Luna. La identificación de asuntos comunes, entre ellos el de la vagina dentada, refuerza la relación entre el mito del Popol Vuh y las representaciones de Izapa y Copán. A la vez, revela detalles poco conocidos sobre el simbolismo sexual presente en los mitos cosmogónicos mesoamericanos.The birds represented at Stela 25 of Izapa and Copan ball court are the starting point for the analysis of the mythological topic focused on the vagina dentata in Ancient Mesoamerica, as well as their expressions on art and narrative. A large body of mythological narratives is used as a basis for the examination of the "Siete Guacamayo" story included in the Popol Vuh, which is interpreted as part of a widely extended myth related with the creation of the Sun and the Moon. The identification of common issues, as the vagina dentata topic, strengthens the links between the Popol Vuh myth and the Izapa and Copan representations. It also reveals less known details on the sexual symbolism included in the Mesoamerican cosmogonic myths.

  10. Factors affecting long-term outcome of irradiation in carcinoma of the vagina

    International Nuclear Information System (INIS)

    Objective: This report evaluates prognostic and technical factors affecting outcome of patients with primary carcinoma of the vagina treated with definitive radiation therapy. Methods and Materials: A retrospective analysis was performed on records of 212 patients with histologically confirmed carcinoma of the vagina treated with irradiation. Results: Tumor stage was the most significant prognostic factor; actuarial 10-year disease-free survival was 94% for Stage 0 (20 patients), 80% for Stage I (59 patients), 55% for Stage IIA (63 patients), 35% for Stage IIB (34 patients), 38% for Stage III (20 patients), and 0% for Stage IV (15 patients). All in situ lesions except one were controlled with intracavitary therapy. Of the patients with Stage I disease, 86% showed no evidence of vaginal or pelvic recurrence; most of them received interstitial or intracavitary therapy or both, and the addition of external-beam irradiation did not significantly increase survival or tumor control. In Stage IIA (paravaginal extension) and IIB (parametrial involvement) 66% and 56% of the tumors, respectively, were controlled with a combination of brachytherapy and external-beam irradiation; 13 of 20 (65%) Stage III tumors were controlled in the pelvis. Four patients with Stage IV disease (27%) had no recurrence in the pelvis. The total incidence of distant metastases was 13% in Stage I, 30% in Stage IIA, 52% in Stage IIB, 50% in Stage III, and 47% in Stage IV. The dose of irradiation deliven Stage IV. The dose of irradiation delivered to the primary tumor or the parametrial extension was of relative importance in achieving successful results. In patients with Stage I disease, brachytherapy alone achieved the same local tumor control (80-100%) as in patients receiving external pelvic irradiation (78-100%) as well. In Stage II and III there was a trend toward better tumor control (57-80%) with combined external irradiation and brachytherapy than with the latter alone (33-50%) (p = 0.42). The incidence of grade 2-3 complications (12%) correlated with the stage of the tumor and type of treatment given. Conclusion: Radiation therapy is an effective treatment for patients with vaginal carcinoma, particularly Stage I. More effective irradiation techniques, including optimization of dose distribution combining external irradiation and interstitial brachytherapy in tumors beyond Stage I, are necessary to enhance locoregional tumor control. The high incidence of distant metastases emphasizes the need for earlier diagnosis and effective systemic cytotoxic agents to improve survival in these patients

  11. High Frequency of Human Papillomavirus Detection in the Vagina Before First Vaginal Intercourse Among Females Enrolled in a Longitudinal Cohort Study

    OpenAIRE

    Shew, Marcia L.; Weaver, Bree; Tu, Wanzhu; Tong, Yan; Fortenberry, J. Dennis; Brown, Darron R.

    2012-01-01

    Background.?Genital human papillomavirus (HPV) infection is believed to be primarily sexually transmitted. Few studies have documented the detection of HPV in the vagina before first vaginal intercourse.

  12. Denys-Drash syndrome, septated vagina and low level of anti-Mullerian hormone in male neonate

    OpenAIRE

    Lee, Hong Jun; Yeom, Jung-Sook; Park, Ji Sook; Park, Eun Sil; Seo, Ji-Hyun; Lim, Jae Young; Park, Chan-Hoo; Woo, Hyang-Ok; Youn, Hee-Shang

    2014-01-01

    There is a wide variety of genital abnormalities observed in patients with Denys-Drash syndrome (DDS). WT1 is thought to influence the genes related to genital development and mutations in this gene have been associated with DDS. DDS should be considered in the differential diagnosis of newborns with genital anomalies. In contrast to other conditions with 46,XY disorders of sex development, individuals with DDS often have duplicated genital organs (a double vagina, cervix or uterus). A double...

  13. Ultrastructural study of the neovagina following the utilization of human amniotic membrane for treatment of congenital absence of the vagina

    OpenAIRE

    Bleggi-Torres L.F.; Werner B.; Piazza M.J.

    1997-01-01

    We present an ultrastructural study of the utilization of human amniotic membrane in the treatment of congenital absence of the vagina in 10 patients. All patients were surgically treated with application of an amniotic membrane graft using the modified McIndoe and Bannister technique. Sixty days after surgery, samples of the vaginal neo-epithelium were collected for transmission electron microscopy analysis. The ultrastructural findings consisted of a lining of mature squamous epithelium ind...

  14. Efecto del sistema de crianza (extensivo vssemiintensivo) del macho cabrío, sobre la obtención de semen mediante vagina artificial

    OpenAIRE

    Edctor Manuel Prado, V. U.; Edn Orihuela Trujillo, Agust U.; Salvador Lozano Trejo; Mar\\u00EDa Isabel P\\u00E9rez Le\\u00F3n

    2001-01-01

    Con el propósito de evaluar el efecto del sistema de crianza (extensivo vs semiintensivo) del macho cabrío, en el entrenamiento para colecta de semen mediante vagina artificial, se utilizaron ocho animales criollos, de dos años de edad, con experiencia sexual; cuatro habían sido criados bajo condiciones extensivas, y los restantes bajo un manejo semiintensivo. Todos recibieron ocho sesiones de entrenamiento, exponiéndoles en forma individual, dos veces por semana, ante una he...

  15. Topometric preparation and interstitial gamma-therapy of patients with recurrencies and metastases of uterine cancer to the vagina

    International Nuclear Information System (INIS)

    The developed technique of preradiation topometry in patients with recurrencies and metastases of uterine cancer to the vagina allows to visualize boundaries of soft-tissue tumor formation and to specify its localization, sizes and relation with urethra, rectum, urinary bladder. Results of topometric investigation are used for individual planning of interstitial radiotherapy: fabrication of fixing instruments, choice of a number of sources, their activity, position, and exposure duration

  16. [Case report of live threatening complications due to self insertion of foreign body into the vagina for masturbation purpose].

    Science.gov (United States)

    Kuzaka, Boles?aw; Kobry?, Andrzej; Niemierko, Maciej; Czaplicki, Maciej

    2009-01-01

    Authors have reported a case report of life threatening complications due to insertion of foreign bodies into the vagina, because of masturbation purpose. In this case subsequently came to perforation of the urinary bladder by the huge calculus that developed over the foreign body, and next to the peritoneum with development peritonitis and acute renal insufficiency with the need of dialysotherapy. After a number of surgical operations, the patient with a definitive percutaneous nephrostomy was discharged. PMID:20043585

  17. In vivo Raman spectroscopy of human uterine cervix: exploring the utility of vagina as an internal control

    Science.gov (United States)

    Shaikh, Rubina; Dora, Tapas Kumar; Chopra, Supriya; Maheshwari, Amita; Kedar K., Deodhar; Bharat, Rekhi; Krishna, C. Murali

    2014-08-01

    In vivo Raman spectroscopy is being projected as a new, noninvasive method for cervical cancer diagnosis. In most of the reported studies, normal areas in the cancerous cervix were used as control. However, in the Indian subcontinent, the majority of cervical cancers are detected at advanced stages, leaving no normal sites for acquiring control spectra. Moreover, vagina and ectocervix are reported to have similar biochemical composition. Thus, in the present study, we have evaluated the feasibility of classifying normal and cancerous conditions in the Indian population and we have also explored the utility of the vagina as an internal control. A total of 228 normal and 181 tumor in vivo Raman spectra were acquired from 93 subjects under clinical supervision. The spectral features in normal conditions suggest the presence of collagen, while DNA and noncollagenous proteins were abundant in tumors. Principal-component linear discriminant analysis (PC-LDA) yielded 97% classification efficiency between normal and tumor groups. An analysis of a normal cervix and vaginal controls of cancerous and noncancerous subjects suggests similar spectral features between these groups. PC-LDA of tumor, normal cervix, and vaginal controls further support the utility of the vagina as an internal control. Overall, findings of the study corroborate with earlier studies and facilitate objective, noninvasive, and rapid Raman spectroscopic-based screening/diagnosis of cervical cancers.

  18. Phospholipase activity of Candida albicans isolated from vagina and urine samples

    Directory of Open Access Journals (Sweden)

    Sanaz Miry

    2010-10-01

    Full Text Available Introduction and objective: Candida albicans is the most virulent among the Candida species, and can cause several forms of candidiasis in human. Extracellular phospholipases in C. albicans is discussed as one of the virulence factors. The present study, focused on extracellular phospholipase activities in different isolates of C. albicans isolated from vagina and urine samples from Ahvaz, Iran. In addition, phospholipase activities were compared in C. albicans isolated from two different sources. Materials and methods: In the present study, phospholipase activity of 100 isolates of C. albicans with urine and vaginitis origin was demonstrated using Sabouraud's dextrose agar supplemented with egg yolk. Results: The phospholipase activity was detected in all tested isolates with a high level in Pz<0.70. In the present study phospholipase activity with higher Pz values was more common in vaginal isolates (84.7% isolates with Pz value <0.70 compared with 75% in urine isolates. Conclusion: In the present study, 100% clinical isolates of C. albicans from vaginitis and urine samples demonstrated phospholipase activity.

  19. Radiotherapy of primary carcinoma of the vagina: Clinical and histopathological variables associated with survival

    International Nuclear Information System (INIS)

    434 cases of primary vaginal carcinoma were treated from 1950 to 1984 at the Irradiation Department of the University Clinic for Obstetrics and Gynecology, Vienna. The five-year survival rate for various clinical stages is as follows: Stage I 76.7%, stage II 44.5%, stage III 31%, stage IV 18.2%. In this retrospective study 110 patients seen from 1975 to 1984 were reviewed in detail and evaluated with a view toward their clinical and morphological aspects and survival rates. Patients up to the age of 60 have a five-year survival rate of 50%, those over 75 years of age reach only 34.3%. If the carcinoma was discovered in a routine check up the survival rate is 61.1%, whereas in cases with symptoms the rate decreases to 36.9%. Survival differences were also observed for patients with a carcinoma in the upper third of the vagina (61.1%) versus patients with a carcinoma in the lower third (33.3%); for patients with well-differentiated tumours (62.5%) versus patients with grades II and III (41.5% and 34.9%). It can be seen, that with brachytherapy local control of the carcinoma can be achieved with excellent results in early stages. Treatment of patients with more advanced carcinomas should include external beam therapy. The importance of gynecological screening especially for older women is emphasized. (orig.)

  20. Squamous carcinoma of the vagina: treatment, complications, and long-term follow-up

    International Nuclear Information System (INIS)

    Seventy-five cases of primary squamous cell carcinoma of the vagina treated at the University of Pennsylvania are reviewed with long-term follow-up presented. These comprised 2.5% of all female genital malignancies treated during 1958 to 1980 inclusive. Patients treated during that time with non-squamous cell cancers have been excluded. Patients are analyzed with regard to stage, therapy, complications, and survival. Sixty-five percent of patients were stage I or II. Five-year survival for the entire group was 45%. Patients treated with radical surgery other than exenteration did well, with 7 of 8 surviving 5 years. Serious treatment complications were mostly related to radiation therapy and primarily involved the bowel and bladder. Three patients died of complications. Recurrence carried a grave prognosis as 30 of 33 patients with recurrence died of disease. Most recurrences were diagnosed within the first year following treatment. Patients with advanced disease were more likely to have distant recurrences. Although radiation therapy is generally the treatment of choice, radical surgery can yield excellent results when used in carefully selected patients. With meticulous attention to radiation dosage and technique it is hoped that treatment morbidity can be reduced. Optimal treatment of advanced disease may require some form of adjuvant systemic therapy

  1. [Streptococcus agalactiae (GBS)--the characteristic of isolated strains from productive women's vagina].

    Science.gov (United States)

    Wolny, Katarzyna; Go?da-Matuszak, Ewa

    2010-01-01

    The main aim of my research: to determine the frequency of colonisation Streptococcus agalactiae from productive women's vagina, an evaluation of usefulness microbiological diagnostic methods to detect GBS, to define serotype of analysed strains of S. agalactiae. After all, I tried to define fenotypic differential, biochemical and antimicrobial susceptibility between GBS with and without hemolysis. All of strains S. agalactiae (n = 380) belong to bacteria Gram(+), they had B serologic group and didn't produce catalase. On the basis of TSA+5% sheep blood streptococcus with beta-hemolysis grew like a small, grey and shiny colonies with a narrow, bright ring. On the same base we had S. agalactiae without beta-hemolysis, in examine material--6% (n = 22). On the basis of Strepto B ID S. agalactiae grew like a small, round red colonies and on the base Granada agar like an orange, white colonies. The level of colonisation S. agalactiae was 22% (380GBS/1727women). Identification of analysed strains of S. agalactiae was made by test API 20 Strep. The susceptibility was examined to ampicilin, azithromycin, erythromycin, clindamycin, chloramphenicol, doxycyclin, cotrimoxasol, ciprofloxacin. Serotypes III (50%), Ia (18%) and V (14%) prevailed. PMID:20873487

  2. Lactobacillus fornicalis sp. nov., isolated from the posterior fornix of the human vagina.

    Science.gov (United States)

    Dicks, L M; Silvester, M; Lawson, P A; Collins, M D

    2000-05-01

    Twelve strains isolated from the posterior fornix fluid of the human vagina were identified as Lactobacillus johnsonii, Lactobacillus acidophilus, Lactobacillus gallinarum and Lactobacillus crispatus based on numerical analyses of total soluble cell protein profiles and randomly amplified polymorphic DNA (RAPD)-PCR banding patterns. Five strains grouped with the type strains of Lactobacillus gasseri (DSM 20077T) and Lactobacillus jensenii (DSM 20557T) at r > or = 0.83 in one protein profile cluster, well separated from the other species included in this study. However, numerical analysis of the RAPD-PCR banding patterns of representative strains selected from the L. gasseri-L. jensenii protein cluster clearly indicated that they belong to two different species. Four strains (TV 1010, TG 1013, TV 1018T and TV 1045) grouped into another well separated protein profile cluster at r > or = 0.87. Strains selected from this cluster displayed very similar RAPD-PCR banding patterns and clustered at R2 > or = 0.78, separate from the other strains examined. Sequencing of the 16S rRNA of two representative strains, TV 1018T and TG 1013, of this group indicated that it represents a new member of rRNA group I Lactobacillus, which includes Lactobacillus delbrueckii, the type of the genus, and close relatives Lactobacillus acetotolerans, Lactobacillus kefiranofaciens, Lactobacillus iners, L. jensenii, L. crispatus, L. acidophilus, Lactobacillus helveticus, Lactobacillus amylovorus, Lactobacillus hamsteri, L. johnsonii, L. gasseri and Lactobacillus amylolyticus. The name Lactobacillus fornicalis sp. nov. is proposed for strains TV 1010 (DSM 13172), TG 1013, TV 1018T and TV 1045, with strain TV 1018T (= DSM 13171T = ATCC 700934T) as the type. PMID:10843070

  3. The Lactobacillus flora in vagina and rectum of fertile and postmenopausal healthy Swedish women

    Directory of Open Access Journals (Sweden)

    Stjernquist Martin

    2011-05-01

    Full Text Available Abstract Background Lactobacillus species are the most often found inhabitants of vaginal ecosystem of fertile women. In postmenopausal women with low oestrogen levels, Lactobacillus flora is diminishing or absent. However, no studies have been performed to investigate the correlation between oestrogen levels and the lactobacilli in the gut. The aim of the present study was to investigate the relation in healthy women between vaginal and rectal microbial flora as well as possible variations with hormone levels. Methods Vaginal and rectal smears were taken from 20 healthy fertile women, average 40 years (range 28-49 years, in two different phases of the menstrual cycle, and from 20 postmenopausal women, average 60 years (range 52-85 years. Serum sex hormone levels were analyzed. Bacteria from the smears isolated on Rogosa Agar were grouped by Randomly Amplified Polymorphic DNA and identified by multiplex PCR and partial 16S rRNA gene sequencing. Results Lactobacillus crispatus was more often found in the vaginal flora of fertile women than in that of postmenopausal (p = 0.036. Fifteen of 20 fertile women had lactobacilli in their rectal smears compared to 10 postmenopausal women (p = 0.071. There was no correlation between the number of bacteria in vagina and rectum, or between the number of bacteria and hormonal levels. Neither could any association between the presence of rectal lactobacilli and hormonal levels be found. Conclusion Lactobacillus crispatus was more prevalent in the vaginal flora of fertile women, whereas the Lactobacillus flora of rectum did not correlate to the vaginal flora nor to hormonal levels.

  4. Self-assessment of anatomy, sexual sensitivity, and function of the labia and vagina.

    Science.gov (United States)

    Schober, Justine M; Alguacil, Nieves Martin; Cooper, R Scott; Pfaff, Donald W; Meyer-Bahlburg, Heino F L

    2015-04-01

    Patient perceptions of genital esthetics are motivating requests for plastic surgeries that could change sexual sensitivity. There is little information about the sensitivities of labial and introital sites. The aim of this study is to assess the relationship between sexual sensitivity and self-reported sizes of labial and introital sites. Sixty-two healthy, sexually active, adult women (mean age 37.9, range 21-60) with no history of genital or vaginal surgery gave written consent to participate in this study. A modified version of Self-Assessment of Genital Anatomy and Sexual Function (L-SAGASF-F) was used to assess labial and introital size. Site-specific sensation was rated on Likert scales of 1-5. Anatomical locations were compared for ratings. Of 62 responders, 84% (52) described their labia as "average-sized," 11% (7) described their labia minora and 13% (8) their labia majora as "large", and 3% (2) and 5% (3) as "small". Sexual pleasure ratings were "moderate" (median value: 3.0 for external genitalia and vaginal lumen) or "strong" (median value: 4.0 for the interior vagina). Significantly higher rankings related to the vaginal opening (P=0.007). Orgasm intensity for stimulation of the external genitalia progressively increased toward the vaginal opening, from 1.0 to 3.0 (P=0.001); vaginal ratings showed a similar progression, from 2.0 at the external luminal margin to 3.0 in the deep interior (P<0.0001). Orgasm effort scores were intermediate (median: 3.0), uniform throughout the external and internal areas (P=0.626). Ratings for labial and introital sensitivity, regardless of self-reported size, were very similar to those at other genital sites for sexual pleasure. Surgical excision of labial and introital structures could modify sexual sensation. PMID:25683213

  5. Functional anatomy of the vagina muscles in the adult western conifer seed bug, Leptoglossus occidentalis (Heteroptera: Coreidae), and its implication for the egg laying behaviour in insects.

    Science.gov (United States)

    Chiang, R G

    2010-07-01

    The anatomy of the female reproductive tract and the nerve-evoked contractions of the vagina muscles and their association with the ovipositor in the western conifer seed bug, Leptoglossus occidentalis (Heidemann) are investigated for the first time. The reproductive tract consists of a set of paired telotrophic ovaries, each containing seven ovarioles, located in the anterior lateral regions of the abdomen. Each ovary is attached to a lateral oviduct which spans most of the abdomen to attach to a relatively short common oviduct that joins the vagina near the rear of the animal. The vagina is associated with a pair of bilaterally symmetrical muscles attached at their posterior ends to lateral extensions of sternite VIII, the valvifer of the Type II ovipositor. From this attachment site, the muscles fan out medially and anteriorly to converge along the dorsal midline of the vagina up to the base of the common oviduct. Vagina muscles respond to a single stimulation of their motor nerves by producing a smooth contraction lasting approximately 1 s. With increasing frequencies of stimulation, the muscle contractions summate to create a tetanic response. The muscles are fatigue resistant being able to maintain the same degree of tension for up to 10 min at 10 Hz stimulation. Visual observation shows that other muscles associated with the valves of the ovipositor behave in a similar fashion to that of the vagina muscles from which the tension recordings were obtained. Fatigue-resistant vagina muscles are discussed in relation to copulation, sperm transport and this insect's ability to deposit a series of eggs directly onto the surface of a conifer needle in a manner by which eight or more blunt-ended eggs are packed end-to-end in a single row. PMID:20172047

  6. xpression of estrogen and progesterone receptor genes in endometrium, myometrium and vagina of postmenopausal women treated with estriol / Expresión de los genes receptores de estrógeno y progesterona en el endometrio, miometrio y vagina en mujeres posmenopáusicas tratadas con estriol

    Scientific Electronic Library Online (English)

    Magdalena, Bry& #347; ; Krzysztof, Szytto; Hanna, Romanowicz-Makowska; Zbigniew, Dobrowolski; Izabela, Mastowska; Wanda, Krajewska.

    Full Text Available CONTEXTO Y OBJETIVO: El estriol es un estrógeno con un efecto estimulatorio bastante más débil sobre la proliferación endometrial que el estradiol. Se realizó un estudio para determinar los efectos de una terapia vaginal de 14 días con estriol, sobre el nivel de receptores de estrógeno (ER) y recept [...] ores de progesterona (PR), comparado con mujeres sin esa terapia. La expresión de los genes de ER y PR se analizó en el endometrio, miometrio y vagina de mujeres posmenopáusicas tratadas con estriol. DISEÑO Y UBICACIÓN: Estudio Transversal analítico, en el Instituto de Investigación del Hospital de la Madre Polaca en Lodz, Polonia. MÉTODOS: Se incluyeron veintisiete mujeres posmenopáusicas (de 57 a 74 años) en el estudio. Todas ellas estaban en espera de una histerectomía per vaginam o de cirugía plástica de la vagina y del perineo debido a un prolapso del útero. La expresión de genes de los receptores ER y PR se estableció por la técnica de RT-PCR. RESULTS: En las pacientes tratadas con estriol en comparación con el grupo de control, se observó un aumento significativo de la expresión del gen de ER en el endometrio y la vagina, mientras que un aumento de la expresión del gen de PR se encontró en el endometrio. De todas formas, en el examen histológico del endometrio, se diagnosticó estimulación estrogénica de bajo y medio grado en el 21.4% y en el 14.3% de las mujeres tratadas con estriol, respectivamente. CONCLUSIONES: Los resultados obtenidos sugieren que un tratamiento de 14 días con estriol en pacientes, aunque aumentan el nivel de ER y de PR mRNA, tiene muy poco o ningún efecto sobre la proliferación endometrial. Abstract in english CONTEXT AND OBJECTIVE: Estriol is an estrogen with considerably weaker stimulatory effects on endometrial proliferation than estradiol. A study was conducted to determine the level of estrogen receptors (ERs) and progesterone receptors (PRs) in women who received 14-day vaginal estriol therapy, comp [...] ared with those who did not receive this therapy. ER and PR gene expression was analyzed in the endometrium, myometrium and vagina of postmenopausal women treated with estriol. DESIGN AND SETTING: Analytical cross-sectional study, at the Research Institute of the Polish Mothers' Memorial Hospital, Lodz, Poland. METHODS: Twenty-seven postmenopausal women (57-74 years of age) were included in the study. All of them were waiting for per vaginam hysterectomy or plastic surgery on the vagina and perineum because of uterine prolapse. ER and PR gene expression was determined by means of the technique of reverse transcription polymerase chain reaction (RT-PCR). RESULTS: In the estriol-treated patients, in comparison with the control group, a significant increase in ER gene expression was observed in the endometrium and vagina, while enhanced PR gene expression was found in the endometrium. However, under histological examination of the endometrium, estrogen stimulation of low and medium degree was diagnosed for 21.4% and 14.3% of the estriol-treated women, respectively. CONCLUSION: The results obtained suggest that the women who received 14 days of treatment with vaginal estriol had higher ER and PR mRNA levels. No difference between these groups regarding endometrial proliferation was observed.

  7. Avaliação dosimétrica de uma combinação de aplicadores para braquiterapia de tumores do colo uterino com acometimento da porção distal da vagina / Dosimetric evaluation of a combination of brachytherapy applicators for uterine cervix cancer with involvement of the distal vagina

    Scientific Electronic Library Online (English)

    Roger Guilherme Rodrigues, Guimarães; Heloisa de Andrade, Carvalho; Silvia Radwanski, Stuart; Rodrigo Augusto, Rubo; Rodrigo Migotto, Seraide.

    2009-08-01

    Full Text Available OBJETIVO: Avaliar uma alternativa de braquiterapia para tumores do colo uterino acometendo a porção distal da vagina, sem aumentar os riscos de toxicidade. MATERIAIS E MÉTODOS: Estudo teórico comparando três diferentes aplicadores de braquiterapia intracavitária de alta taxa de dose: sonda intrauter [...] ina e cilindro vaginal (SC); sonda e anel associado ao cilindro vaginal (SA+C) e um aplicador virtual com sonda, anel e cilindro vaginal em um único conjunto (SAC). Foram prescritas doses de 7 Gy no ponto A e 5 Gy na superfície ou a 5 mm de profundidade na mucosa vaginal, mantendo as doses nos pontos de reto, bexiga e sigmoide abaixo dos limites de tolerância. Foram comparados os volumes englobados pelas isodoses de 50% (V50), 100% (V100), 150% (V150) e 200% (V200), respectivamente. RESULTADOS: Tanto SA+C quanto SAC apresentaram melhor distribuição de dose quando comparados ao aplicador SC. A distribuição de dose obtida com SA+C foi semelhante à do aplicador SAC, sendo V150 e V200 cerca de 50% maiores para SA+C, todavia, dentro do cilindro. CONCLUSÃO: A utilização de SA+C em uma única aplicação em dois tempos pode ser uma alternativa de tratamento para pacientes que apresentam tumores de colo uterino com acometimento distal da vagina. Abstract in english OBJECTIVE: To evaluate an alternative brachytherapy technique for uterine cervix cancer involving the distal vagina, without increasing the risk of toxicity. MATERIALS AND METHODS: Theoretical study comparing three different high-dose rate intracavitary brachytherapy applicators: intrauterine tandem [...] and vaginal cylinder (TC); tandem/ring applicator combined with vaginal cylinder (TR+C); and a virtual applicator combining both the tandem/ring and vaginal cylinder in a single device (TRC). Prescribed doses were 7 Gy at point A, and 5 Gy on the surface or at a 5 mm depth of the vaginal mucosa. Doses delivered to the rectum, bladder and sigmoid colon were kept below the tolerance limits. Volumes covered by the isodoses, respectively, 50% (V50), 100% (V100), 150% (V150) and 200% (V200) were compared. RESULTS: Both the combined TR+C and TRC presented a better dose distribution as compared with the TC applicator. The TR+C dose distribution was similar to the TRC dose, with V150 and V200 being about 50% higher for TR+C (within the cylinder). CONCLUSION: Combined TR+C in a two-time single application may represent an alternative therapy technique for patients affected by uterine cervix cancer involving the distal vagina.

  8. Avaliação dosimétrica de uma combinação de aplicadores para braquiterapia de tumores do colo uterino com acometimento da porção distal da vagina Dosimetric evaluation of a combination of brachytherapy applicators for uterine cervix cancer with involvement of the distal vagina

    Directory of Open Access Journals (Sweden)

    Roger Guilherme Rodrigues Guimarães

    2009-08-01

    Full Text Available OBJETIVO: Avaliar uma alternativa de braquiterapia para tumores do colo uterino acometendo a porção distal da vagina, sem aumentar os riscos de toxicidade. MATERIAIS E MÉTODOS: Estudo teórico comparando três diferentes aplicadores de braquiterapia intracavitária de alta taxa de dose: sonda intrauterina e cilindro vaginal (SC; sonda e anel associado ao cilindro vaginal (SA+C e um aplicador virtual com sonda, anel e cilindro vaginal em um único conjunto (SAC. Foram prescritas doses de 7 Gy no ponto A e 5 Gy na superfície ou a 5 mm de profundidade na mucosa vaginal, mantendo as doses nos pontos de reto, bexiga e sigmoide abaixo dos limites de tolerância. Foram comparados os volumes englobados pelas isodoses de 50% (V50, 100% (V100, 150% (V150 e 200% (V200, respectivamente. RESULTADOS: Tanto SA+C quanto SAC apresentaram melhor distribuição de dose quando comparados ao aplicador SC. A distribuição de dose obtida com SA+C foi semelhante à do aplicador SAC, sendo V150 e V200 cerca de 50% maiores para SA+C, todavia, dentro do cilindro. CONCLUSÃO: A utilização de SA+C em uma única aplicação em dois tempos pode ser uma alternativa de tratamento para pacientes que apresentam tumores de colo uterino com acometimento distal da vagina.OBJECTIVE: To evaluate an alternative brachytherapy technique for uterine cervix cancer involving the distal vagina, without increasing the risk of toxicity. MATERIALS AND METHODS: Theoretical study comparing three different high-dose rate intracavitary brachytherapy applicators: intrauterine tandem and vaginal cylinder (TC; tandem/ring applicator combined with vaginal cylinder (TR+C; and a virtual applicator combining both the tandem/ring and vaginal cylinder in a single device (TRC. Prescribed doses were 7 Gy at point A, and 5 Gy on the surface or at a 5 mm depth of the vaginal mucosa. Doses delivered to the rectum, bladder and sigmoid colon were kept below the tolerance limits. Volumes covered by the isodoses, respectively, 50% (V50, 100% (V100, 150% (V150 and 200% (V200 were compared. RESULTS: Both the combined TR+C and TRC presented a better dose distribution as compared with the TC applicator. The TR+C dose distribution was similar to the TRC dose, with V150 and V200 being about 50% higher for TR+C (within the cylinder. CONCLUSION: Combined TR+C in a two-time single application may represent an alternative therapy technique for patients affected by uterine cervix cancer involving the distal vagina.

  9. Experimental inoculation model of Walker 256 carcinoma into vagina and cervix uteri of female rats Modelo experimental de Tumor de Walker 256 em vagina e colo de útero de ratas

    OpenAIRE

    Nara Macedo Botelho Brito; Marcus Vinicius Henriques Brito; Rita de Kássia Vidigal Carvalho; Lia Tavares de Moura Brasil Matos; Thiago Sousa Veloso; Diego Matos de Vasconcelos; Rosângela Baía Brito

    2007-01-01

    PURPOSE: To establish an inoculation model of Walker 256 carcinoma on cervix uteri and vagina of rats. METHODS: Fifteen female rats were used, and assigned to three groups each one with five rats: group A - rats with 4x10(6) cells of Walker 256 carcinoma without acid acetic inoculation; group B - rats with 2x10(6) cells of Walker 256 carcinoma with acid acetic inoculation and group C: rats with 4x10(6) cells of Walker 256 carcinoma with acid acetic inoculation. The day before tumor cells inoc...

  10. The effect of copaiba balsam on Walker 256 carcinoma inoculated into the vagina and uterine cervix of female rats Efeito do óleo de copaíba no tumor de Walker 256 inoculado em vagina e colo de útero de ratas fêmeas

    OpenAIRE

    Nara Macedo Botelho Brito; Marcus Vinicius Henriques Brito; Rita de Kássia Vidigal Carvalho; Lia Tavares de Moura Brasil Matos; Rodolfo Costa Lobato; Suelen Costa Correa; Rosângela Baía Brito

    2010-01-01

    PURPOSE: To verify the copaiba balsam (Copaifera officinalis) effect on Walker 256 carcinoma inoculated into vagina and uterine cervix of rats. METHODS: Eighteen female Wistar rats weighing between 180-250g were used, distributed into 2 groups (GCop, GC). On the 1st day of the experiment, 0.3 ml of Walker 256 carcinoma (2x10(6) concentration) was inoculated in both groups; on the 3rd day of the experiment, it was given 4.8 ml/kg of distilled water to the GC group, and 4.8 ml/kg of copaiba bal...

  11. Definitive radiation therapy for invasive carcinoma of the vagina. Impact of high-dose rate intracavitary brachytherapy

    International Nuclear Information System (INIS)

    This study was designed to evaluate the efficacy of definitive radiation therapy (RT) for invasive carcinoma of the vagina. Twenty-six patients with invasive carcinoma of the vagina who received RT were studied retrospectively. The median age was 68 years. The pathologic subtype of vaginal carcinoma was squamous cell carcinoma in 24 patients, adenosquamous cell carcinoma in one patient, and adenocarcinoma in one patient. The distribution of clinical stage according to the International Federation of Gynecology and Obstetrics staging system was as follows: stage I, seven patients; stage II, 10 patients, stage III, seven patients; and stage IVA, two patients. Twenty patients received external beam radiation therapy (EBRT) combined with high-dose rate intracavitary brachytherapy (HDR-ICBT), and three received EBRT alone. The remaining three patients with stage I disease were given HDR-ICBT alone. The median dose was 50 Gy for EBRT, and 23 Gy for HDR-ICBT. Systemic chemotherapy was administered concurrently with RT to three patients. The median follow-up was 90 months. The initial rate of response to RT was 100%, and complete remission was attained in 21 patients (81%). The 5-year overall survival rate (OS) and the median survival time of the 26 patients were 57% and 97 months, respectively. The 5-year OS for the three patients who received HDR-ICBT alone was 100%. Severe toxicity occurred in three patients-grade 3 rectal hemorrhage in one, grade 3 cystitis in one, and grge in one, grade 3 cystitis in one, and grade 4 cystitis in one. Our results demonstrated that definitive RT with HDR-ICBT is effective for invasive carcinoma of the vagina, with acceptable toxicity. (author)

  12. Clinico-radiobiological evaluation of the correlation between dose and injury rate in radiotherapy of endometrial metastases into the vagina

    International Nuclear Information System (INIS)

    Problem of choosing optimum radiobiological model is studied for prediction of the probability of arising radiation-induced complications in case of radiotherapy of patients of corpus uteri carcinoma with metastases into the vagina. Based on the results of radiotherapy (remote plus contact; contact) at different doses the radiobiological modes time dose-fractionation factor is found to be usable in case of radiobiological assesment of various dose fractionation variants and choice of isoeffective regimes under clinical conditions. It is easy in case and makes it possible to predict truly the probability of arising early and late radiation-induced complication

  13. Normal tissue reactions to high dose-rate intracavitary irradiation of the vagina with different fractionation schedules and dose levels

    International Nuclear Information System (INIS)

    The radiation reactions in the normal tissues of the vagina, rectum and bladder were studied in 166 patients receiving prophylactic vaginal high dose-rate intracavitary irradiation. Most reactions were observed in the vaginal mucosa included in the intracavitary target and only a few in the rectum and bladder in close proximity to the same target. The influence of the total dose, the dose per fraction and the overall treatment time, summarized as the Cumulative Radiation Effect (CRE), correlated well to the rate of reactions after a correction of the formula for late effects. (orig.)

  14. Dosimetric evaluation of a combination of brachytherapy applicators for uterine cervix cancer with involvement of the distal vagina; Avaliacao dosimetrica de uma combinacao de aplicadores para braquiterapia de tumores do colo uterino com acometimento da porcao distal da vagina

    Energy Technology Data Exchange (ETDEWEB)

    Guimaraes, Roger Guilherme Rodrigues [Real e Benemerita Sociedade Portuguesa de Beneficencia, Sao Paulo, SP (Brazil). Servico de Radioterapia Estereotactica; Carvalho, Heloisa de Andrade; Stuart, Silvia Radwanski; Rubo, Rodrigo Augusto [Universidade de Sao Paulo (USP), SP (Brazil). Hospital das Clinicas. Servico de Radioterapia], e-mail: handrade@hcnet.usp.br; Seraide, Rodrigo Migotto [Centro de Oncologia Campinas, SP (Brazil)

    2009-07-15

    Objective: To evaluate an alternative brachytherapy technique for uterine cervix cancer involving the distal vagina, without increasing the risk of toxicity. Materials And Methods: Theoretical study comparing three different high-dose rate intracavitary brachytherapy applicators: intrauterine tandem and vaginal cylinder (TC); tandem/ring applicator combined with vaginal cylinder (TR+C); and a virtual applicator combining both the tandem/ring and vaginal cylinder in a single device (TRC). Prescribed doses were 7 Gy at point A, and 5 Gy on the surface or at a 5 mm depth of the vaginal mucosa. Doses delivered to the rectum, bladder and sigmoid colon were kept below the tolerance limits. Volumes covered by the isodoses, respectively, 50% (V50), 100% (V100), 150% (V150) and 200% (V200) were compared. Results: Both the combined TR+C and TRC presented a better dose distribution as compared with the TC applicator. The TR+C dose distribution was similar to the TRC dose, with V150 and V200 being about 50% higher for TR+C (within the cylinder). Conclusion: Combined TR+C in a two-time single application may represent an alternative therapy technique for patients affected by uterine cervix cancer involving the distal vagina. (author)

  15. Effect of seminal plasma on post-thaw quality and functionality of corriedale ram sperm obtained by electroejaculation and artificial vagina.

    Science.gov (United States)

    Ledesma, A; Manes, J; Ríos, G; Aller, J; Cesari, A; Alberio, R; Hozbor, F

    2015-06-01

    We have already shown that seminal collection method affects seminal plasma composition and sperm quality in Corriedale rams. In this study, we evaluated the effect of seminal plasma collected by electroejaculation or artificial vagina on sperm resistance to cryodamage. Seminal plasma of five rams of the Corriedale breed collected by artificial vagina or electroejaculation was added before freezing to sperm cells collected by the two methods, and post-thaw quality parameters were evaluated. We found that seminal plasma has no effect on sperm resistance to cryodamage. However, we observed significantly higher percentages of sperm with intact and functional plasma membrane, intact acrosome and greater fertilizing potential after thawing in samples obtained by electroejaculation. This study demonstrates that sperm collected by electroejaculation are more resistant to damage caused by cryopreservation than those collected by artificial vagina. PMID:25684063

  16. Dosimetric evaluation of a combination of brachytherapy applicators for uterine cervix cancer with involvement of the distal vagina

    International Nuclear Information System (INIS)

    Objective: To evaluate an alternative brachytherapy technique for uterine cervix cancer involving the distal vagina, without increasing the risk of toxicity. Materials And Methods: Theoretical study comparing three different high-dose rate intracavitary brachytherapy applicators: intrauterine tandem and vaginal cylinder (TC); tandem/ring applicator combined with vaginal cylinder (TR+C); and a virtual applicator combining both the tandem/ring and vaginal cylinder in a single device (TRC). Prescribed doses were 7 Gy at point A, and 5 Gy on the surface or at a 5 mm depth of the vaginal mucosa. Doses delivered to the rectum, bladder and sigmoid colon were kept below the tolerance limits. Volumes covered by the isodoses, respectively, 50% (V50), 100% (V100), 150% (V150) and 200% (V200) were compared. Results: Both the combined TR+C and TRC presented a better dose distribution as compared with the TC applicator. The TR+C dose distribution was similar to the TRC dose, with V150 and V200 being about 50% higher for TR+C (within the cylinder). Conclusion: Combined TR+C in a two-time single application may represent an alternative therapy technique for patients affected by uterine cervix cancer involving the distal vagina. (author)

  17. Definitive radiotherapy for carcinoma of the vagina: outcome and prognostic factors

    International Nuclear Information System (INIS)

    Purpose: Primary carcinoma of the vagina is an uncommon tumor. Because of the long-standing interest in this disease at our institution a substantial number of patients with this disease has been accumulated, and this retrospective review was performed to define disease outcome, to delineate significant prognostic factors, and to provide treatment guidelines. Methods and Materials: This was a retrospective review of 301 patients with vaginal carcinoma (271 with squamous cell and 30 with adenocarcinoma) who received definitive radiotherapy between 1953 and 1991. Prognostic factors for outcome (local control, pelvic control, metastatic relapse, survival, and complications) were evaluated using univariate and multivariate techniques. Results: Patients disease was staged using the International Federation of Gynecology and Obstetrics (FIGO) system, and stages were distributed as follows: 0, 37 (12%); I, 65 (22%); II, 122 (40%); III, 60 (20%); and, IVA, 17 (6%). Treatment varied according to stage, with brachytherapy predominating for early disease but external beam playing a prominent role for more advanced disease. Patients with in situ disease received brachytherapy alone or transvaginal orthovoltage irradiation. For Stage I, brachytherapy alone was used in 25, external beam and brachytherapy in 38, and transvaginal alone in 2. For Stage II, brachytherapy alone was used in 20, external and brachytherapy in 66, and external irradiation alone in 36. For Stage III, externaiation alone in 36. For Stage III, external and brachytherapy was used in 15, and external alone in 45. Two patients with Stage IVA received brachytherapy alone, 10 received a combination of external and brachytherapy, and 6 received external irradiation alone. Total doses ranged from 10 to 154 Gy (mean 74.7 Gy, median 70.0 Gy), but only 18 (6%) received less than 55 Gy. At a median follow-up of 13 years, the 5-, 10-, 15-, 20-, and 25-year survival rates were 60%, 49%, 38%, 29%, and 23%, respectively. Beyond 5 years the survival rates relative to those for age-matched females in the general population were between 50 and 65%. Actuarial local recurrence rates were 23%, 26%, and 26% at 5, 10, and 15 years. Actuarial pelvic relapse rates were 26%, 30%, and 31% at 5, 10, and 15 years, and metastatic rates at those times were 15%, 18%, and 18%. Adenocarcinoma (nonclear cell) was a significantly worse disease than squamous cell carcinoma. The major determinants of local control for squamous carcinoma were tumor bulk (specified by size in centimeters, or by FIGO stage), tumor site (upper lesions faring better than others), and tumor circumferential location (lesions involving the posterior wall faring worse). Tumor bulk was an important determinant of metastatic relapse, but failure to achieve local control was also an independently significant determinant of metastases. Salvage after first relapse was uncommon and the survival rate at 5 years after relapse was only 12%. Serious complications occurred in 39 patients with an actuarial incidence of 19% at 20 years. Conclusion: Vaginal carcinoma poses a formidable therapeutic challenge. The disease is heterogeneous with respect to its prognostic factors. Nonclear cell adenocarcinoma has an extremely poor prognosis and should be distinguished from squamous carcinoma. Both external beam and brachytherapy play crucial roles in management and most patients with disease beyond in situ should receive a significant component of external irradiation prior to brachytherapy

  18. The effect of copaiba balsam on Walker 256 carcinoma inoculated into the vagina and uterine cervix of female rats / Efeito do óleo de copaíba no tumor de Walker 256 inoculado em vagina e colo de útero de ratas fêmeas

    Scientific Electronic Library Online (English)

    Nara Macedo Botelho, Brito; Marcus Vinicius Henriques, Brito; Rita de Kássia Vidigal, Carvalho; Lia Tavares de Moura Brasil, Matos; Rodolfo Costa, Lobato; Suelen Costa, Correa; Rosângela Baía, Brito.

    2010-04-01

    Full Text Available OBJETIVO: Verificar o efeito do óleo de copaíba da espécie Copaifera officinalis no carcinoma de Walker 256 inoculado em vagina e colo de útero de ratas. MÉTODOS: Foram utilizadas 18 ratas da linhagem Wistar, pesando entre 180-250g, distribuídas em dois grupos (CCop, GC). No 1º dia de experimento, e [...] m ambos os grupos foi inoculado 0,3ml de tumor de Walker 256 na concentração de 2x10(6); no 3º dia após essa inoculação, foi iniciada a administração de água destilada na dose de 4,8 ml/kg ao GC, e copaíba na dose de 4,8 ml/kg ao GCop. No 12º dia foi realizada a eutanásia das ratas e ressecado o tumor, sendo este pesado e averiguado seu volume. Os dados obtidos foram submetidos à análise estatística pelo método ANOVA. RESULTADOS: Observou-se que o óleo de copaíba apresentou um potencial inibitório negativo de 70%. CONCLUSÃO: O óleo de copaíba estimulou o crescimento tumoral. Abstract in english PURPOSE: To verify the copaiba balsam (Copaifera officinalis) effect on Walker 256 carcinoma inoculated into vagina and uterine cervix of rats. METHODS: Eighteen female Wistar rats weighing between 180-250g were used, distributed into 2 groups (GCop, GC). On the 1st day of the experiment, 0.3 ml of [...] Walker 256 carcinoma (2x10(6) concentration) was inoculated in both groups; on the 3rd day of the experiment, it was given 4.8 ml/kg of distilled water to the GC group, and 4.8 ml/kg of copaiba balsam to the GCop group. On the 12th day, euthanasia was performed and the tumor was grafted, being weighted and verified its volume. The data were submitted to statistical analysis with ANOVA test. RESULTS: It was observed that copaiba balsam presented a negative inhibitory potential of 70%. CONCLUSION: The copaiba balsam stimulated the tumor growth.

  19. The effect of copaiba balsam on Walker 256 carcinoma inoculated into the vagina and uterine cervix of female rats Efeito do óleo de copaíba no tumor de Walker 256 inoculado em vagina e colo de útero de ratas fêmeas

    Directory of Open Access Journals (Sweden)

    Nara Macedo Botelho Brito

    2010-04-01

    Full Text Available PURPOSE: To verify the copaiba balsam (Copaifera officinalis effect on Walker 256 carcinoma inoculated into vagina and uterine cervix of rats. METHODS: Eighteen female Wistar rats weighing between 180-250g were used, distributed into 2 groups (GCop, GC. On the 1st day of the experiment, 0.3 ml of Walker 256 carcinoma (2x10(6 concentration was inoculated in both groups; on the 3rd day of the experiment, it was given 4.8 ml/kg of distilled water to the GC group, and 4.8 ml/kg of copaiba balsam to the GCop group. On the 12th day, euthanasia was performed and the tumor was grafted, being weighted and verified its volume. The data were submitted to statistical analysis with ANOVA test. RESULTS: It was observed that copaiba balsam presented a negative inhibitory potential of 70%. CONCLUSION: The copaiba balsam stimulated the tumor growth.OBJETIVO: Verificar o efeito do óleo de copaíba da espécie Copaifera officinalis no carcinoma de Walker 256 inoculado em vagina e colo de útero de ratas. MÉTODOS: Foram utilizadas 18 ratas da linhagem Wistar, pesando entre 180-250g, distribuídas em dois grupos (CCop, GC. No 1º dia de experimento, em ambos os grupos foi inoculado 0,3ml de tumor de Walker 256 na concentração de 2x10(6; no 3º dia após essa inoculação, foi iniciada a administração de água destilada na dose de 4,8 ml/kg ao GC, e copaíba na dose de 4,8 ml/kg ao GCop. No 12º dia foi realizada a eutanásia das ratas e ressecado o tumor, sendo este pesado e averiguado seu volume. Os dados obtidos foram submetidos à análise estatística pelo método ANOVA. RESULTADOS: Observou-se que o óleo de copaíba apresentou um potencial inibitório negativo de 70%. CONCLUSÃO: O óleo de copaíba estimulou o crescimento tumoral.

  20. Ultrastructural study of the neovagina following the utilization of human amniotic membrane for treatment of congenital absence of the vagina

    Directory of Open Access Journals (Sweden)

    L.F. Bleggi-Torres

    1997-07-01

    Full Text Available We present an ultrastructural study of the utilization of human amniotic membrane in the treatment of congenital absence of the vagina in 10 patients. All patients were surgically treated with application of an amniotic membrane graft using the modified McIndoe and Bannister technique. Sixty days after surgery, samples of the vaginal neo-epithelium were collected for transmission electron microscopy analysis. The ultrastructural findings consisted of a lining of mature squamous epithelium indicating the occurrence of metaplasia of the amniotic epithelium into the vaginal epithelium. The cells were arranged in layers as in the normal vaginal epithelium, i.e., superficial, intermediate and deep layers. There were desmosomes and cytoplasmic intermediate cytokeratin filaments, as well as some remnant features of the previous amniotic epithelium. These findings suggest that human amniotic membrane is able to complete metaplasia into squamous cells but the mechanism of this cellular transformation is unknown

  1. Ultrastructural study of the neovagina following the utilization of human amniotic membrane for treatment of congenital absence of the vagina

    Scientific Electronic Library Online (English)

    L.F., Bleggi-Torres; B., Werner; M.J., Piazza.

    1997-07-01

    Full Text Available We present an ultrastructural study of the utilization of human amniotic membrane in the treatment of congenital absence of the vagina in 10 patients. All patients were surgically treated with application of an amniotic membrane graft using the modified McIndoe and Bannister technique. Sixty days af [...] ter surgery, samples of the vaginal neo-epithelium were collected for transmission electron microscopy analysis. The ultrastructural findings consisted of a lining of mature squamous epithelium indicating the occurrence of metaplasia of the amniotic epithelium into the vaginal epithelium. The cells were arranged in layers as in the normal vaginal epithelium, i.e., superficial, intermediate and deep layers. There were desmosomes and cytoplasmic intermediate cytokeratin filaments, as well as some remnant features of the previous amniotic epithelium. These findings suggest that human amniotic membrane is able to complete metaplasia into squamous cells but the mechanism of this cellular transformation is unknown

  2. Genital panics: constructing the vagina in women's qualitative narratives about pubic hair, menstrual sex, and vaginal self-image.

    Science.gov (United States)

    Fahs, Breanne

    2014-06-01

    An emerging body of research targets women's relationship to their genitals, particularly as pubic hair removal and the promotion of female genital surgeries increase in popularity and visibility. This study asked women to discuss their subjective feelings about three related but distinct genital attitudes: pubic hair grooming, sex during menstruation, and genital/vaginal self-image. Specifically, this study applied thematic analysis to qualitative interviews with a community sample of 20 women (mean age=34, SD=13.35) from diverse ages, races, and sexual identity backgrounds to illuminate seven themes in women's narratives about their vaginas: (1) "dirty" or "gross"; (2) needing maintenance; (3) unknown or frustrating; (4) unnatural; (5) comparative; (6) ambivalent; (7) affirmative. Overwhelmingly, women used strong emotional language when discussing their genitals, often evoking descriptions of anxiety, excess, and need for control. Fusions between sexuality and body image, and connections between "genital panics" and internalized racism, sexism, and homophobia, also appeared. PMID:24958655

  3. Disturbances in the vagina development of the white rat off spring under the effect of X-ray irradiation

    International Nuclear Information System (INIS)

    120 embryos of white rats from 13 to 22 days old irradiated with X-rays at 12-th-14-th days of embryogenesis. The embryos are classified in the series of sagittal, transversal, frontal cross sections and are dyed with conVentional techniques. The formation of paramesonefral tracts is obserVed in all experimental animals. The violations of the vaginal development manifest themselves in the time delay of connection of paramesonefral tracts resorption of medial partition between connected tracts, separation of the sinus vaginal part from the genitourinary sinus, recanalization of vaginal epithelial band. More serious injuries are presented by agenesis of the sinus part of vagina and atresia of the organ in the form of its transverse separation by a partition

  4. Analysis of study rezults of biopsies of the vagina mucous membrane in women with recurrent genital prolapse

    Directory of Open Access Journals (Sweden)

    Banakhevich R.M.

    2014-06-01

    Full Text Available The study involved 53 women with recurrent genital prolapse. The average age of the women studied was 62,8±9,8 years, age of women of the control group was 57,2±6,3 years (p>0,05. Features of expression of estrogen and progesterone receptors levels, markers of cell proliferation and collagen in the biopsy of the vagina mucous membrane were estimated. In the vaginal mucosa of patients with recurrent prolapse expression of Ki-67 markers of proliferative activity was not established. According to the study general lowering of estrogen receptors by 76,2% in patients with recurrent genital prolapse was established, whereas in patients of the control group level of estrogen receptors in the unchanged epithelium and stroma was positive in 100% of cases. In patients with recurrent genital prolapse the decrease of expression of progesterone receptors by 83,4% was identified.

  5. Nonoxynol-9 berberine plural gel has little effect on expression of SLPI, SP-D and lactoferrin in mice’s vagina

    Directory of Open Access Journals (Sweden)

    Huang Guangying

    2013-01-01

    Full Text Available Background: The most frequently used spermicide Nonoxynol-9 (N-9 in the clinic alters the vaginal flora, which will result in an increased risk of opportunistic infection. So development of a novel spermicidal and microbicidal drug appears to be inevitable. Vaginal local immune is an important part of vaginal flora. Secretory leukocyte protease inhibitor (SLPI, surfactant proteins D (SP-D, and lactoferrin (LF are anti-microbial molecules with important roles in immune system of female vaginas. Objective: To observe effect of a vaginal spermicide nonoxynol-9 (N-9 berberine plural gel on the expression of SLPI SP-D and LF in mice’s vaginas. Materials and Methods: Female BABL/C mice were randomly divided into following 5 groups: normal control group, blank gel group, berberine gel group, 12% N-9 gel group and N-9 berberine plural gel group. Estradiol benzoate at physiological dose was done by hypodermic injection to every group’s mice. After 72h, drug gels were separately injected into the mice’s vaginas, while immunohistochemistry and Western blot were taken to detect the expression of the 3 indexes in mice’s vaginas respectively after 24h and 72h of gel injection. Results: The differences in the three indexes between normal control group and blank gel group were not significant statistically (p>0.05. The expression of the three indexes in 12% N-9 gel group was decreased compared to that in blank gel group (p0.05. Also, the three index's level of 24h and 72h in sub observation groups after treatment were without statistical significance (p>0.05. Conclusion: Application of N-9 berberine plural gel had little impact on antimicrobial peptides in normal mice’s vaginas.

  6. Caracterização de leveduras isoladas da vagina e sua associação com candidíase vulvovaginal em duas cidades do sul do Brasil Characterization of yeasts isolated from the vagina and their association with vulvovaginal candidíasis in two cities of the South of Brazil

    Directory of Open Access Journals (Sweden)

    Magda Helena S. H. Ferrazza

    2005-02-01

    Full Text Available OBJETIVOS: avaliar a distribuição de espécies de leveduras isoladas da vagina em duas localidades do sul do Brasil e comparar o perfil de suscetibilidade in vitro destas leveduras a antifúngicos usados na prática clínica. MÉTODOS: todas as mulheres atendidas entre janeiro e junho de 2004 para exames rotineiros de amostras vaginais, independente de serem sintomáticas ou não, foram incluídas neste estudo. Foram excluídas as que apresentavam imunodeficiências como AIDS ou outras infecções genitais. Amostras de conteúdo vaginal dessas mulheres (Jaraguá do Sul - SC (n=130 e Maringá - PR (n=97 foram cultivadas. As leveduras isoladas foram identificadas e submetidas ao teste de suscetibilidade aos antifúngicos fluconazol, nistatina e anfotericina B. RESULTADOS: a freqüência de cultura positiva para levedura foi semelhante nas duas localidades, aproximadamente 24%. Candida albicans foi a espécie prevalente, mas sua freqüência diferiu: em SC correspondeu a 77,4% das leveduras e foi a mais freqüente tanto nas mulheres sintomáticas quanto nas assintomáticas. Já no PR foi 50,0%, com predomínio mais evidente nos casos sintomáticos. Observamos altos índices de suscetibilidade ao fluconazol e anfotericina B, porém 51,1% das leveduras apresentaram suscetibilidade dependente da dose (S-DD para nistatina. C. albicans mostrou maior tendência de resistência à nistatina (52,8% de S-DD do que as espécies não-albicans (44,4%. CONCLUSÕES: nossos dados mostram diferenças regionais quanto à espécie de levedura em amostras vaginais. Sugerem que a determinação da espécie pode ter implicação clínica, considerando as diferenças quanto à suscetibilidade, principalmente à nistatina, e que poderiam ter importância no manejo da candidíase vulvovaginal.PURPOSE: to evaluate the distribution of yeast species isolated from the vagina in two cities of the South of Brazil and compare the in vitro susceptibility profile of these yeasts against some antifungals, which are used in clinical routine. METHODS: all women attended from January to June 2004 for vaginal routine examinations, independent of being symptomatic or not were included in the study. Only those who presented immunodeficiency like AIDS or any other genital infection were excluded. Samples of vaginal discharge from the women (Jaraguá do Sul - SC (n=130 and Maringá - PR (n=97 were cultivated. The yeasts were identified and submitted to the susceptibility test against the antifungals fluconazole, nystatin and amphotericin B. RESULTS: the frequency of positive cultures for yeasts was the same in both cities; C. albicans was the most prevalent species (about 24%, but its frequency was different: in SC it corresponded to 77.4% of the yeasts both in symptomatic and asymptomatic women and in PR it was 50.0% with predominance in symptomatic women. We observed high rates of susceptibility to fluconazole and amphotericin B, but 51.1% of the yeasts presented dose-dependent susceptibility (DDS to nystatin. C. albicans showed a higher tendency to be nystatin resistant (52.8% DDS than non-albicans species (44.4%. CONCLUSIONS: our data showed geographic differences among the species of yeasts isolated from the vagina and suggest that this fact has clinical relevance considering the differences in susceptibility, especially regarding nystatin, which could be important for the management of vulvovaginal candidiasis.

  7. Caracterização de leveduras isoladas da vagina e sua associação com candidíase vulvovaginal em duas cidades do sul do Brasil / Characterization of yeasts isolated from the vagina and their association with vulvovaginal candidíasis in two cities of the South of Brazil

    Scientific Electronic Library Online (English)

    Magda Helena S. H., Ferrazza; Márcia L. Ferrarezi, Maluf; Marcia Edilaine Lopes, Consolaro; Cristiane Suemi, Shinobu; Terezinha Inez Estivalet, Svidzinski; Márcia Regina, Batista.

    2005-02-01

    Full Text Available OBJETIVOS: avaliar a distribuição de espécies de leveduras isoladas da vagina em duas localidades do sul do Brasil e comparar o perfil de suscetibilidade in vitro destas leveduras a antifúngicos usados na prática clínica. MÉTODOS: todas as mulheres atendidas entre janeiro e junho de 2004 para exames [...] rotineiros de amostras vaginais, independente de serem sintomáticas ou não, foram incluídas neste estudo. Foram excluídas as que apresentavam imunodeficiências como AIDS ou outras infecções genitais. Amostras de conteúdo vaginal dessas mulheres (Jaraguá do Sul - SC (n=130) e Maringá - PR (n=97)) foram cultivadas. As leveduras isoladas foram identificadas e submetidas ao teste de suscetibilidade aos antifúngicos fluconazol, nistatina e anfotericina B. RESULTADOS: a freqüência de cultura positiva para levedura foi semelhante nas duas localidades, aproximadamente 24%. Candida albicans foi a espécie prevalente, mas sua freqüência diferiu: em SC correspondeu a 77,4% das leveduras e foi a mais freqüente tanto nas mulheres sintomáticas quanto nas assintomáticas. Já no PR foi 50,0%, com predomínio mais evidente nos casos sintomáticos. Observamos altos índices de suscetibilidade ao fluconazol e anfotericina B, porém 51,1% das leveduras apresentaram suscetibilidade dependente da dose (S-DD) para nistatina. C. albicans mostrou maior tendência de resistência à nistatina (52,8% de S-DD) do que as espécies não-albicans (44,4%). CONCLUSÕES: nossos dados mostram diferenças regionais quanto à espécie de levedura em amostras vaginais. Sugerem que a determinação da espécie pode ter implicação clínica, considerando as diferenças quanto à suscetibilidade, principalmente à nistatina, e que poderiam ter importância no manejo da candidíase vulvovaginal. Abstract in english PURPOSE: to evaluate the distribution of yeast species isolated from the vagina in two cities of the South of Brazil and compare the in vitro susceptibility profile of these yeasts against some antifungals, which are used in clinical routine. METHODS: all women attended from January to June 2004 for [...] vaginal routine examinations, independent of being symptomatic or not were included in the study. Only those who presented immunodeficiency like AIDS or any other genital infection were excluded. Samples of vaginal discharge from the women (Jaraguá do Sul - SC (n=130) and Maringá - PR (n=97)) were cultivated. The yeasts were identified and submitted to the susceptibility test against the antifungals fluconazole, nystatin and amphotericin B. RESULTS: the frequency of positive cultures for yeasts was the same in both cities; C. albicans was the most prevalent species (about 24%), but its frequency was different: in SC it corresponded to 77.4% of the yeasts both in symptomatic and asymptomatic women and in PR it was 50.0% with predominance in symptomatic women. We observed high rates of susceptibility to fluconazole and amphotericin B, but 51.1% of the yeasts presented dose-dependent susceptibility (DDS) to nystatin. C. albicans showed a higher tendency to be nystatin resistant (52.8% DDS) than non-albicans species (44.4%). CONCLUSIONS: our data showed geographic differences among the species of yeasts isolated from the vagina and suggest that this fact has clinical relevance considering the differences in susceptibility, especially regarding nystatin, which could be important for the management of vulvovaginal candidiasis.

  8. Histologia e morfometria das glândulas das junções infundíbulo-magno e útero-vagina de codorna doméstica Histology and morphometry of the infundibulum-magnum and uterus-vaginal junctions of spotted quails

    OpenAIRE

    Carime Moraes; Silvana Martinez Baraldi-Artoni; Maria Rita Pacheco; Daniela Oliveira; Lizandra Amoroso; Alex Luís Sagula

    2009-01-01

    A análise comparativa das glândulas armazenadoras de espermatozóides das junções infundíbulo-magno e útero-vagina do oviduto da codorna Nothura maculosa foi realizada durante a fase reprodutiva. As aves foram eutanasiadas por inalação com éter etílico, após a pesagem. Após a laparotomia e o deslocamento cranial do esterno, foram coletadas amostras de dois centímetros da junção infundíbulo-magno e útero-vagina. Os fragmentos foram fixados em solução de Bouin por 24 horas e,...

  9. Effects of depomedroxyprogesterone acetate on the development and maintenance of Candida albicans in the vagina of oophorectomized Wistar rats (Rattus norvegicus)

    OpenAIRE

    Agenor Storti-Filho; Edilson Damke; Márcia Aparecida Carrara; Marcia Regina Batista; Lucélia Donatti; Cinthia Gandolfi Boer; Terezinha Inez Estivalet Svizdinski; Márcia Edilaine Lopes Consolaro

    2011-01-01

    The objective of this study was to determine the effect of medroxyprogesterone acetate (DMPA) on the development and maintenance of Candida albicans in the vagina of oophorectomized Wistar rats. The animals were divided into negative control groups (NCG), which received injections of sterile saline; positive control groups (PCG), which were given injections of estradiol valerate; and progesterone groups (PG), which were given injections of Depo-Provera®. After one week of hormonal induction,...

  10. Persistence of Lactobacillus fermentum RC-14 and Lactobacillus rhamnosus GR-1 but Not L. rhamnosus GG in the Human Vagina as Demonstrated by Randomly Amplified Polymorphic DNA

    OpenAIRE

    Gardiner, Gillian E.; Heinemann, Christine; Bruce, Andrew W.; Beuerman, Dee; Reid, Gregor

    2002-01-01

    Lactobacillus rhamnosus GR-1 and L. fermentum RC-14 are well-characterized probiotic strains with efficacy in the prevention and treatment of urogenital infections in women. The aim of the present study was to apply a molecular biology-based methodology for the detection of these strains and L. rhamnosus GG (a commercially available intestinal probiotic) in the human vagina in order to assess probiotic persistence at this site. Ten healthy women inserted vaginally a capsule containing either ...

  11. Immunoglobulin G, Plasma Cells, and Lymphocytes in the Murine Vagina after Vaginal or Parenteral Immunization with Attenuated Herpes Simplex Virus Type 2

    OpenAIRE

    Parr, Earl L.; Parr, Margaret B.

    1998-01-01

    This investigation evaluated immunity to vaginal herpes simplex virus type 2 (HSV-2) infection after local or parenteral immunization with attenuated HSV-2. Vaginal immunization induced sterilizing immunity against challenge with a high dose of wild-type virus, whereas parenteral immunizations protected against neurologic disease but did not entirely prevent infection of the vagina. Vaginal immunization caused 86- and 31-fold increases in the numbers of immunoglobulin G (IgG) plasma cells in ...

  12. In silico vs in vitro analysis of primer specificity for the detection of Gardnerella vaginalis, Atopobium vaginae and Lactobacillus spp.

    Directory of Open Access Journals (Sweden)

    Henriques Ana

    2012-11-01

    Full Text Available Abstract Background Bacterial vaginosis (BV is a common pathology of women in reproductive age that can lead to serious health complications, and is associated with shifts in the normal microflora from predominance of Lactobacillus spp. to a proliferation of other anaerobes such as G. vaginalis and A vaginae, which can be detected by PCR. The optimal PCR pathogen detection assay relies mainly on the specificity and sensitivity of the primers used. Findings Here we demonstrate that in silico analytical testing of primer specificity is not a synonym to in vitro analytical specificity by testing a range of published and newly designed primers with both techniques for the detection of BV-associated microorganisms. Conclusions By testing primer in vitro specificity with a sufficient range of bacterial strains, we were able to design primers with higher specificity and sensitivity. Also by comparing the results obtained for the newly designed primers with other previously published primers, we confirmed that in silico analysis is not sufficient to predict in vitro specificity. As such care must be taken when choosing the primers for a detection assay.

  13. Characterisation of the bacterial microbiota of the vagina of dairy cows and isolation of pediocin-producing Pediococcus acidilactici

    Directory of Open Access Journals (Sweden)

    Wang Yvonne

    2013-01-01

    Full Text Available Abstract Background Uterine infections in dairy cows lower profitability of dairy operations. Infections of the reproductive tract are related to the overgrowth of pathogenic bacteria during the first three weeks after parturition. However, alterations in the vaginal microbiota composition in the first weeks after parturition remain poorly documented. Results In this study, bacteria isolated from the vagina of healthy pregnant, and infected postpartum cows were characterised by random amplification of polymorphic DNA (RAPD analysis and partial 16S ribosomal RNA (rDNA gene sequencing. Populations of bacilli and lactic acid bacteria of the genera Enterococcus, Lactobacillus, and Pediococcus were present in both healthy and infected cows. Infected cows had a significant increase in the vaginal enteric bacteria population which consisted mainly of Escherichia coli. Three E. coli isolates harboured the gene coding for Shiga-like-toxin (SLT I or II. Several isolates of the Pediococcus acidilactici were found to produce the bacteriocin pediocin AcH/PA-1. Quantitative PCR analyses of vaginal mucus samples collected from ten metritic cows before and after parturition confirmed the presence of the Lactobacillus group (Lactobacillus spp., Pediococcus spp., Leuconostoc spp., and Weissella spp.; Enterobacteriaceae, E. coli, and bacilli. The presence of the pediocin AcH/PA-1 structural gene and SLT genes were also confirmed with qPCR. Conclusions In conclusion, overgrowth of pathogenic bacteria, particularly E. coli, after parturition likely contributes to the development of metritis. Our microbiota analysis extends the information related to the composition of commensal bacteria in the bovine female reproductive tract and may facilitate the development of novel intervention strategies for prevention of uterine infections in dairy cows.

  14. Il Linguaggio della Vagina

    OpenAIRE

    Marco Menicocci

    2011-01-01

    La cultura delle masse è oggi una cultura prevalentemente visuale. Tra i segni visuali da tempo in crescita è quello, caratteristico, della depilazione pubica femminile. Originata all'interno della cultura porno come segno di passività, questa pratica si è incontrata con i simboli della pulizia, dell'igiene, del rispetto, trasformando così il proprio significato in quello di autonomia e libertà. Così le donne possono depilarsi per scopi erotici minimizzando però la valenza sessuale del gesto ...

  15. Carcinoma of the vagina

    International Nuclear Information System (INIS)

    Twenty-two patients with Stage I through IV primary vaginal squamous cell carcinomas treated for cure with radiation therapy are reviewed, with particular emphasis on the relationship of dose to complications and local control. All but 2 patients received 4000 to 6000 rad whole pelvis irradiation plus at least one radium application. Local control was 91%, with an absolute 2-year disease-free survival of 82%. The degree of anaplasia was found to influence prognosis, with all local and distant failures resulting from high-grade lesions. The complication rate was modest, with no fistulae or serious bowel complications. An analysis of total dose (external plus radium) with respect to local failure and complications showed that no major complications occurred at a combined dose below 9000 rad. An analysis of the individual contributions of external irradiation and radium implants showed that all but one very minor complication occurred at a radium dose of 4000 rad or higher. From these data, overall treatment planning and total dose recommendations are made

  16. Carcinoma of the vagina

    International Nuclear Information System (INIS)

    There are two major difficulties in the management of vaginal carcinoma. First, irradiation alone has not provided adequate results in stage III and stage IV disease. Pelvic failures and distant metastases occur in half of the patients with advanced disease. The second problem is that the results of therapy for patients with nonepithelial tumors (sarcomas, melanomas) are poor

  17. Il Linguaggio della Vagina

    Directory of Open Access Journals (Sweden)

    Marco Menicocci

    2011-12-01

    Full Text Available La cultura delle masse è oggi una cultura prevalentemente visuale. Tra i segni visuali da tempo in crescita è quello, caratteristico, della depilazione pubica femminile. Originata all'interno della cultura porno come segno di passività, questa pratica si è incontrata con i simboli della pulizia, dell'igiene, del rispetto, trasformando così il proprio significato in quello di autonomia e libertà. Così le donne possono depilarsi per scopi erotici minimizzando però la valenza sessuale del gesto tramite la tendenza alla super-igiene.

  18. Conceptual knowledge of vesico-vagina fistula among parents, teachers and counsellors of senior secondary students in Warri South local government area of Delta State, Nigeria

    Directory of Open Access Journals (Sweden)

    Imoukhede M.O

    2015-04-01

    Full Text Available Background: VVF is leakages of urine and faeces through the vagina. It is rampant in the North and the Eastern parts of Nigeria due to the forced marriage of girls at about the age of eleven. This may be attributed to their small pelvises which have resulted in harmful reproductive health practice. The disability and suffering from obstetric fistula remains a neglected issue in global health. Aim: This study seeks to explore the conceptual knowledge of vesico-vagina fistula (VVF among parents, teachers and counselors of senior secondary school students in Warri South local government area of Delta state. Methods: A survey design was used. Random sampling method was used to select a total number of six hundred respondents including parents, teachers and counselors that participated in the study, but only five hundred and eleven questionnaires were retrieved. The questionnaire was divided into two sections containing information on demography and selected variables for the study. Data was analyzed using descriptive statistics of Anova and t-tests. Result: the study revealed that there is no significant difference in the conceptual knowledge of VVF among parents, teachers and counselors of senior secondary school students either by educational status or location. Conclusion: It can be concluded that parents, teachers and counselors of senior secondary school have very little knowledge about VVF. There is need for educational programmes on VVF to enlighten them about VVF and the danger it poses.

  19. Normal tissue tolerance to external beam radiation therapy: The vagina; Dose de tolerance a l'irradiation des tissus sains: le vagin Normal

    Energy Technology Data Exchange (ETDEWEB)

    Magne, N. [Unite de curietherapie, departement de radiotherapie, institut de cancerologie de la Loire, 42 - Saint-Priest-en-Jarez (France); Chargari, C. [Service d' oncologie radiotherapie, hopital d' instruction des armees du Val-de-Grace, 75 - Paris (France); Pointreau, Y. [Clinique d' oncologie radiotherapie, centre Henry-S.-Kaplan, hopital de Bretonneau, CHU de Tours, 37 - Tours (France); Haie-Meder, C. [Service de curietherapie, departement de radiotherapie, institut Gustave-Roussy, 94 - Villejuif (France)

    2010-07-15

    The vagina is a virtual cavity involved in sexual reproduction field. Due to its anatomical location, it may be exposed in whole or in part to ionizing radiation in external radiotherapy and/or brachytherapy of the pelvic region. This review aims to describe the vaginal acute and late side effects due to radiation, probably inadequately reported in the literature. Medline and PubMed literature searches were performed using the keywords -vaginal - radiotherapy - toxicity. The acute and late functional changes after external beam radiation consist mainly of drought. Their incidences are poorly described in the literature and the delivered doses even less. Recommendations are non-existent as the normal tissue complication probability (NTCP). Brachytherapy delivers high and heterogeneous doses, making it difficult to estimate the dose. The concomitant administration of chemotherapy appears to be a factor increasing the risk of toxicity. Modern techniques of conformal radiotherapy with modulated intensity appear to have little impact on this body. Only a maximum dose on each third of the vagina appears to be currently proposed to avoid the risk of side effects. (authors)

  20. Histologia e morfometria das glândulas das junções infundíbulo-magno e útero-vagina de codorna doméstica Histology and morphometry of the infundibulum-magnum and uterus-vaginal junctions of spotted quails

    Directory of Open Access Journals (Sweden)

    Carime Moraes

    2009-04-01

    Full Text Available A análise comparativa das glândulas armazenadoras de espermatozóides das junções infundíbulo-magno e útero-vagina do oviduto da codorna Nothura maculosa foi realizada durante a fase reprodutiva. As aves foram eutanasiadas por inalação com éter etílico, após a pesagem. Após a laparotomia e o deslocamento cranial do esterno, foram coletadas amostras de dois centímetros da junção infundíbulo-magno e útero-vagina. Os fragmentos foram fixados em solução de Bouin por 24 horas e, posteriormente, banhos sucessivos de álcool 70% foram aplicados sobre as amostras. Em seguida, as amostras foram desidratadas em uma série de concentração crescente de alcoóis (80, 90, 95 e 3x100%, diafanizadas em xilol e incluídas em parafina. Cortes histológicos de sete micrômetros de espessura foram obtidos e corados pela técnica da Hematoxilina-eosina (HE, que foram analisados e fotomicrografados em um fotomicroscópio Olympus BX-50. Para a análise morfométrica, foram capturadas imagens das glândulas armazenadoras de espermatozóides da junção infundíbulo-magno e útero-vagina mediante o programa computacional "Image Pro Plus 4.1" da Cibernetics do Brasil, tornando-se possível a quantificação das mesmas. A mucosa da junção infundíbulo-magno apresentou pregas estreitas no infundíbulo e largas no magno, enquanto na junção útero-vagina mostrou-se amplamente pregueada na vagina e mais lisa na porção uterina. O número médio de glândulas armazenadoras de espermatozóides na junção infundíbulo-magno foi maior (11,7 glândulas (PThe comparative analysis of sperm-host glands of infundibulum-magnum and uterus-vagina junctions of Nothura maculosa quail oviduct was done during the reproductive phase. The birds were euthanized with ethyl ether after weight data were taken. After abdominal laparotomy and cranial displacement of the breastbone, two centimeters samples of infundibulum-magnum and uterus-vagina junctions were collected. The samples were fixed in Bouin's solution for twenty four hours and later, successive baths of alcohol 70% were applied on samples and soon afterwards dehydrated in a series of grow concentration alcohols (80, 90, 95 and 3x100%, diaphanized in xylol and included on paraffin. Histological sections with seven micrometers thickness were obtained and stained on Haematoxylin-Eosin (HE technique, then they were analyzed and photomicrographed in a photomicroscope Olympus BX-50. For the morphometry analysis, infundibulum-magnum junctions and uterus-vagina sperm host gland images were captured through a computacional program Image Pro Plus 4.1", Cibernetics Brazil, making it possible to quantify them. The mucosa of the infundibulum-magnum junction presented very narrow folds in the infundibulum and too large in the magnum, while in the uterus-vagina junction was observed widely folds mucous in the vagina and smoother in the uterine portion. The average of sperm host gland in the infundibulum-magnum junction was higher (11.7 glands (P<0.01 compared to the uterus-vagina junction (7.5 glands. It is supposed that the abundance number of sperm host glands in infundibulum-magnum junction allows faster access of the oocyte, after the ovulation of the host spermatozoid ensuring the fertilization.

  1. Histologia e morfometria das glândulas das junções infundíbulo-magno e útero-vagina de codorna doméstica / Histology and morphometry of the infundibulum-magnum and uterus-vaginal junctions of spotted quails

    Scientific Electronic Library Online (English)

    Carime, Moraes; Silvana Martinez, Baraldi-Artoni; Maria Rita, Pacheco; Daniela, Oliveira; Lizandra, Amoroso; Alex Luís, Sagula.

    2009-04-01

    Full Text Available A análise comparativa das glândulas armazenadoras de espermatozóides das junções infundíbulo-magno e útero-vagina do oviduto da codorna Nothura maculosa foi realizada durante a fase reprodutiva. As aves foram eutanasiadas por inalação com éter etílico, após a pesagem. Após a laparotomia e o deslocam [...] ento cranial do esterno, foram coletadas amostras de dois centímetros da junção infundíbulo-magno e útero-vagina. Os fragmentos foram fixados em solução de Bouin por 24 horas e, posteriormente, banhos sucessivos de álcool 70% foram aplicados sobre as amostras. Em seguida, as amostras foram desidratadas em uma série de concentração crescente de alcoóis (80, 90, 95 e 3x100%), diafanizadas em xilol e incluídas em parafina. Cortes histológicos de sete micrômetros de espessura foram obtidos e corados pela técnica da Hematoxilina-eosina (HE), que foram analisados e fotomicrografados em um fotomicroscópio Olympus BX-50. Para a análise morfométrica, foram capturadas imagens das glândulas armazenadoras de espermatozóides da junção infundíbulo-magno e útero-vagina mediante o programa computacional "Image Pro Plus 4.1" da Cibernetics do Brasil, tornando-se possível a quantificação das mesmas. A mucosa da junção infundíbulo-magno apresentou pregas estreitas no infundíbulo e largas no magno, enquanto na junção útero-vagina mostrou-se amplamente pregueada na vagina e mais lisa na porção uterina. O número médio de glândulas armazenadoras de espermatozóides na junção infundíbulo-magno foi maior (11,7 glândulas) (P Abstract in english The comparative analysis of sperm-host glands of infundibulum-magnum and uterus-vagina junctions of Nothura maculosa quail oviduct was done during the reproductive phase. The birds were euthanized with ethyl ether after weight data were taken. After abdominal laparotomy and cranial displacement of t [...] he breastbone, two centimeters samples of infundibulum-magnum and uterus-vagina junctions were collected. The samples were fixed in Bouin's solution for twenty four hours and later, successive baths of alcohol 70% were applied on samples and soon afterwards dehydrated in a series of grow concentration alcohols (80, 90, 95 and 3x100%), diaphanized in xylol and included on paraffin. Histological sections with seven micrometers thickness were obtained and stained on Haematoxylin-Eosin (HE) technique, then they were analyzed and photomicrographed in a photomicroscope Olympus BX-50. For the morphometry analysis, infundibulum-magnum junctions and uterus-vagina sperm host gland images were captured through a computacional program Image Pro Plus 4.1", Cibernetics Brazil, making it possible to quantify them. The mucosa of the infundibulum-magnum junction presented very narrow folds in the infundibulum and too large in the magnum, while in the uterus-vagina junction was observed widely folds mucous in the vagina and smoother in the uterine portion. The average of sperm host gland in the infundibulum-magnum junction was higher (11.7 glands) (P

  2. Abnormal excessive per vagina (PV) bleeding on Esmya-selective progesterone receptor modulator (SPRM) in a symptomatic patient with uterine fibroid.

    Science.gov (United States)

    Matytsina-Quinlan, Lyubov; Matytsina, Laura

    2015-01-01

    A woman in her late 40s presented with excessive per vagina (PV) bleeding and uterine fibroid. She reported excessive PV bleeding after starting Esmya; she was brought in by ambulance to the emergency department with profuse bleeding. Abnormal uterine bleeding (AUB) developed after selective progesterone receptor modulator (SPRM) administration in this symptomatic patient with uterine fibroid. The drug was withheld and surgical treatment considered. Progressive deterioration of PV bleeding after receiving SPRM led to an urgent laparoscopic total hysterectomy, which had to be postponed due to severe anaemia. Surgery took place regardless because the excessive bleeding continued. Histology revealed a 6?cm submucosal uterine fibroid (SMUF) and adenomyosis. Physicians prescribing SPRMs to stop PV bleeding should be aware of potential AUB, which could lead to urgent hysterectomy. The mechanism of action of SPRMs is not clearly understood. Awareness of the side effects of Esmya, such as AUB, must be kept in mind when administering SPRMs. PMID:25976198

  3. Radiation therapy of cancer of the cervix, corpus uteri and vagina at the 1st University Clinic of Gynaecology in Vienna from 1950 to 1979

    International Nuclear Information System (INIS)

    On the occasion of the 30th anniversary of the department of radiotherapy of th 1st University-Clinic of Gynaecology and Obstetrics in Vienna, the results obtained in the treatment of gynaecologic malignancy are presented. During this period, more than 10 000 malignant tumors of the female genital tract were treated, including 3605 cases of cancer of the cervix, 1412 endometrial carcinomas and 397 cases of cancer of the vagina. The principal method of irradiation was local application of radium. Dosage was established empirically after measurements on a model. In addition conventional percutaneous roentgen therapy was used until 1972, when telecobalt irradiation equipment was put into use. Five-year survival rates for cervical, endometrial and vaginal cancer are presented for the years from 1950 through 1972. These results are attributed primarily to intracavitary radium application. Of 2687 cases with cervical cancer 1222 (45.5%) were alive after five years, in stage III cervical cancer 535 out of 1321 (40.5%). The latest international tables published in the Annual Report give a five-year survival rate of 31.7% for stage-III cancer of the cervix. Of 994 cases of endometrial cancer 473 were alive after five years (49.8%), while the Annual Report gives a five-year survival rate of 39.0% for primary irradiation in endometrial cancer. For cancer of the vagina, our five-year survival rate was 42.8% (127 patients out of a total of 297), while the Annual Report gives 37.3% 297), while the Annual Report gives 37.3%. This demonstrates, that the results obtained at the department of radiotherapy of the 1st University Clinic of Gynaecology and Obstetrics in Vienna are better than the international average. Apart from the different methods of treatment the importance of primary radiation therapy in gynaecologic oncology is pointed out, and the side effects and complications are discussed. (orig.)

  4. Effects of depomedroxyprogesterone acetate on the development and maintenance of Candida albicans in the vagina of oophorectomized Wistar rats (Rattus norvegicus)

    Scientific Electronic Library Online (English)

    Agenor, Storti-Filho; Edilson, Damke; Márcia Aparecida, Carrara; Marcia Regina, Batista; Lucélia, Donatti; Cinthia Gandolfi, Boer; Terezinha Inez Estivalet, Svizdinski; Márcia Edilaine Lopes, Consolaro.

    2011-03-01

    Full Text Available O objetivo do presente estudo foi determinar os efeitos do acetato de depomedroxyprogesterona (ADMP) no desenvolvimento e manutenção de Candida albicans na vagina de ratas Wistar ooferectomizadas. Os animais foram divididos em grupos controle negativos (GCN), que receberam injeções de salina estéril [...] ; grupos controle positivos (GCP), que receberam injeções de valerato de estradiol; e grupos progesterona (GP), nos quais foram feitas injeções de Depo-Provera®. Após uma semana da aplicação hormonal, foi induzida a infecção vaginal por C. albicans em todos os grupos, detectada por cultura para leveduras vaginais e esfregaço de Papanicolaou. Foram feitas ainda imagens por microscopia eletrônica de varredura e transmissão para confirmar a infecção pela levedura no GP. Foram observados diferentes níveis de progesterona em GP, entre os valores basais e após a indução hormonal (P Abstract in english The objective of this study was to determine the effect of medroxyprogesterone acetate (DMPA) on the development and maintenance of Candida albicans in the vagina of oophorectomized Wistar rats. The animals were divided into negative control groups (NCG), which received injections of sterile saline; [...] positive control groups (PCG), which were given injections of estradiol valerate; and progesterone groups (PG), which were given injections of Depo-Provera®. After one week of hormonal induction, vaginal infection by C. albicans was induced in all the groups and detected by vaginal yeast culture and Papanicolaou smear. In addition, scanning and transmission electron microscopy images were obtained to confirm the vaginal infection by yeast in PG. A difference in progesterone levels in PG was observed between the basal level and after hormonal induction (P

  5. Histometric Parameters of Uterus and Vagina in Breeder Female Rabbits on the Day After Weaning According to the Ordinal Number of Parturitions / Parámetros Histométricos en Útero y Vagina de Conejas Reproductoras en el día Posterior al Destete Según el Número Ordinal de Partos

    Scientific Electronic Library Online (English)

    José Alfonso, Banda-Herrera; Jesús, Aragón Hernández; Reyes, López Ordaz; Jorge, Hernández Espinosa; Mario, Pérez-Martínez.

    2014-06-01

    Full Text Available El objetivo del presente estudio fue determinar en conejas Nueva Zelanda el efecto del número ordinal de partos sobre algunos parámetros histológicos, en el día posterior al destete. A partir de hembras de primero, segundo y tercer parto se obtuvieron fragmentos de tejido uterino y vaginal los que s [...] e procesaron mediante la técnica de inclusión en parafina para efectuar cortes histológicos. En ocho campos microscópicos capturados con una cámara conectada a un microscopio óptico se midió la altura del epitelio luminal y glandular del endometrio; el grosor del epitelio de la vagina y del miometrio. A partir de los resultados obtenidos se concluye que existen diferencias significativas (p Abstract in english The objective of this study was to establish in New Zealand female rabbits, the effect of ordinal number of parturitions on some histological parameters on the day after weaning. Tissue fragments of uterus and vagina were obtained from females of first, second and third parturitions and were process [...] ed imbedding them in paraffin in order to do histological cuts. In eight microscope fields captured by a camera connected to an optic microscope, the lumen and glandular endometrial epithelium height, as well as the thickness of vaginal and myometrium epithelium thickness were measured. From the results that were obtained it was concluded that there are significant differences (p

  6. Effects of depomedroxyprogesterone acetate on the development and maintenance of Candida albicans in the vagina of oophorectomized Wistar rats (Rattus norvegicus

    Directory of Open Access Journals (Sweden)

    Agenor Storti-Filho

    2011-03-01

    Full Text Available The objective of this study was to determine the effect of medroxyprogesterone acetate (DMPA on the development and maintenance of Candida albicans in the vagina of oophorectomized Wistar rats. The animals were divided into negative control groups (NCG, which received injections of sterile saline; positive control groups (PCG, which were given injections of estradiol valerate; and progesterone groups (PG, which were given injections of Depo-Provera®. After one week of hormonal induction, vaginal infection by C. albicans was induced in all the groups and detected by vaginal yeast culture and Papanicolaou smear. In addition, scanning and transmission electron microscopy images were obtained to confirm the vaginal infection by yeast in PG. A difference in progesterone levels in PG was observed between the basal level and after hormonal induction (PO objetivo do presente estudo foi determinar os efeitos do acetato de depomedroxyprogesterona (ADMP no desenvolvimento e manutenção de Candida albicans na vagina de ratas Wistar ooferectomizadas. Os animais foram divididos em grupos controle negativos (GCN, que receberam injeções de salina estéril; grupos controle positivos (GCP, que receberam injeções de valerato de estradiol; e grupos progesterona (GP, nos quais foram feitas injeções de Depo-Provera®. Após uma semana da aplicação hormonal, foi induzida a infecção vaginal por C. albicans em todos os grupos, detectada por cultura para leveduras vaginais e esfregaço de Papanicolaou. Foram feitas ainda imagens por microscopia eletrônica de varredura e transmissão para confirmar a infecção pela levedura no GP. Foram observados diferentes níveis de progesterona em GP, entre os valores basais e após a indução hormonal (P<0,0001. Neste grupo, 100,0% das ratas contraíram a infecção vaginal na primeira semana, mas não a mantiveram até a terceira semana. A forma farmacêutica de ADMP foi efetiva em induzir as fases de metaestro e diestro do ciclo estral das ratas, da mesma forma que usando progesterona pura. Em contraste com o que ocorre no tratamento com estrógeno, a progesterona não pôde manter a infecção vaginal experimental por C. albicans por um período significativo de tempo.

  7. Effect of semen collection by transrectal massage of accessory sexual glands or artificial vagina on the outcome of breeding soundness examinations of Italian yearling beef bulls.

    Science.gov (United States)

    Sylla, Lakamy; Palombi, Claudio; Stradaioli, Giuseppe; Vagniluca, Antonio; Monaci, Maurizio

    2015-03-15

    Although semen quality is one of the major traits that influence breeding soundness examination outcomes in bulls, field conditions occasionally do not allow for the collection of semen samples by means of an artificial vagina. The aims of the present study were to report the results of a large number of semen collections that were performed via the transrectal massage (TRM) of the accessory sexual glands of Italian yearling beef bulls and compare this semen collection method to the artificial vagina (AV) method in term of breeding soundness examination outcomes; furthermore, we determined whether the breed affected the semen characteristics. In the TRM group (n = 475), the semen samples were collected via TRM of the accessory sexual glands, and in the AV group (n = 502), the AV method was used. In the TRM group, semen samples were obtained from 81.3% of the bulls and penile protrusion was observed in 87.6% of the animals during semen collection. The sperm concentrations (920.5 ± 439.0 vs. 281.0 ± 259.8 × 10(6)/mL) and the percentages of total abnormal spermatozoa (22.8 ± 15.0 vs. 18.8 ± 12.9) were significantly higher in the AV group than those in the TRM group. The percentage of bulls that did not meet the minimum requirement for normal cells (?70%) was 6.2% higher in the AV group than that in the TRM group (P Chianina bulls by TRM exhibited a lower percentage of motile sperm and a higher percentage of abnormal spermatozoa when compared with the other two breeds. The major drawbacks of the TRM technique were the inability to conduct complete evaluation of the libido and mating ability of the yearling bulls, a significant reduction of the number of spermatozoa collected, and an increase in the variability of the semen characteristics due to breed. In conclusion, despite the drawbacks, TRM guarantees that semen evaluation can be conducted in cases in which the semen samples cannot be collected with the AV method. PMID:25488791

  8. Human papillomavirus, p16INK4A, and Ki-67 in relation to clinicopathological variables and survival in primary carcinoma of the vagina

    Science.gov (United States)

    Hellman, K; Lindquist, D; Ranhem, C; Wilander, E; Andersson, S

    2014-01-01

    Background: This study aimed to determine human papillomavirus (HPV) status and to investigate p16INK4A and Ki-67 expression and their correlation with clinical parameters and survival in women with primary carcinoma of the vagina (PCV). Methods: The presence of HPV DNA was evaluated by PCR. Genotyping was performed by Luminex in 68 short-term (?2 years) and long-term (?8 years) PCV survivors. p16INK4A and Ki-67 expression was evaluated by immunohistochemistry. Results: Human papillomavirus DNA was detected in 43% of patients, the majority (63%) of whom were HPV16 positive. High p16INK4A expression was significantly correlated with low histopathological grade (P=0.004), HPV positivity (P=0.032), and long-term survival (P=0.045). High Ki-67 expression was negatively correlated with histopathological grade (Pp16INK4A expression was associated with long-term survival, but the only independent predictors for survival were tumour size and histopathological grade. Our results indicate that p16INK4A and Ki-67 expression might be useful in tumour grading, and that it might be possible to use p16INK4A expression as a marker for HPV positivity, but this has to be further elucidated. PMID:24525695

  9. Detection of hydrogen peroxide-producing Lactobacillus species in the vagina: a comparison of culture and quantitative PCR among HIV-1 seropositive women

    Directory of Open Access Journals (Sweden)

    Balkus Jennifer E

    2012-08-01

    Full Text Available Abstract Background The presence of hydrogen peroxide (H2O2 producing Lactobacillus in the vagina may play a role in controlling genital HIV-1 shedding. Sensitive molecular methods improve our ability to characterize the vaginal microbiota; however, they cannot characterize phenotype. We assessed the concordance of H2O2-producing Lactobacillus detected by culture with quantitative PCR (qPCR detection of Lactobacillus species commonly assumed to be H2O2-producers. Methods Samples were collected as part of a prospective cohort study of HIV-1 seropositive US women. Cervicovaginal lavage specimens were tested for L. crispatus and L. jensenii using 16S rRNA gene qPCR assays. Vaginal swabs were cultured for Lactobacillus and tested for H2O2-production. We calculated a kappa statistic to assess concordance between culture and qPCR. Results Culture and qPCR results were available for 376 visits from 57 women. Lactobacilli were detected by culture at 308 (82% visits, of which 233 of 308 (76% produced H2O2. L. crispatus and/or L. jensenii were detected at 215 (57% visits. Concordance between detection of L. crispatus and/or L. jensenii by qPCR and H2O2-producing Lactobacillus by culture was 75% (kappa = 0.45. Conclusions Among HIV-1 seropositive women, there was a moderate level of concordance between H2O2-producing Lactobacillus detected by culture and the presence of L. crispatus and/or L. jensenii by qPCR. However, one-quarter of samples with growth of H2O2-producing lactobacilli did not have L. crispatus or L. jensenii detected by qPCR. This discordance may be due to the presence of other H2O2-producing Lactobacillus species.

  10. Comparison of Electro Ejaculator and Artificial Vagina on Semen Collection from South African Indigenous Goat Following Assessment by Computer Aided Sperm Analysis

    Directory of Open Access Journals (Sweden)

    Malebogo Audrey Bopape

    2015-03-01

    Full Text Available South African indigenous bucks are raised under extensive conditions and are more likely to reject artificial vagina (AV due to their limited contact with human beings, as they are less handled. The purpose of the study was to compare goat semen collection techniques used for goats based on semen traits of South African indigenous bucks during the natural breeding season. A total of eight South African indigenous bucks were used, four bucks per semen collection technique due to their scarcity. Before semen collection with AV group, ten bucks were trained and exposed to AV. Semen was then collected from both groups over a period of six weeks per individual buck. Semen volume, pH and sperm concentration were evaluated immediately. The Computer Aided Sperm Analysis (CASA assessed the sperm motility rates. Sperm morphology was evaluated using a fluorescence microscope with the aid of eosin-nigrosin staining. Analysis of variance was used to test the differences among the semen collection groups following assessment by CASA. Semen collected with EE resulted in higher semen volume (1.1 mL compared with AV (0.5 mL technique. However, AV technique resulted in higher total sperm motility and rapid movement (91.9% and 48.7%, live sperm (72% and sperm concentration (635.6 × 106 sperm/mL compared with EE (86.3% and 30.4%; 69% and 463.7 × 106 sperm/mL, respectively. There were no significant differences observed in pH and sperm morphology characteristics between two semen collection techniques. Moreover, EE had higher sperm moving in a progressive (53.6% and medium rate compared with AV (41.1% and 21.9% technique. It was concluded that the AV yielded higher total sperm motility rate, sperm concentration and rapid sperm movement compared with EE. Therefore, AV was more suitable for semen collection of South African indigenous bucks, even though training was problematic to such indigenous bucks.

  11. Estrogen and the irradiated vagina

    International Nuclear Information System (INIS)

    The vaginal response of patients to estrogen therapy following radiotherapy for cervical carcinoma is discussed. The authors take exception to the statement of Abitbol and Davenport that irradiation destroys the possibility of a vaginal response to estrogen stimulation

  12. Prevalência de cândida na flora vaginal de mulheres atendidas num serviço de planejamento familiar Prevalence of candida in the vagina of women attended at a family planning service

    Directory of Open Access Journals (Sweden)

    Antônio Aleixo Neto

    1999-01-01

    Full Text Available RESUMO Objetivo: avaliar a prevalência de Candida sp. e a distribuição de suas espécies na flora vaginal de mulheres numa clínica de planejamento familiar. Método: estudo transversal no qual se avaliaram prospectivamente 72 mulheres não-grávidas, com ou sem queixas específicas, sendo coletadas amostras de secreção vaginal para cultura de leveduras, efetuada a medição do pH vaginal e anotados dados de achados do exame ginecológico. Resultados: leveduras pertencentes ao gênero Candida foram encontradas em 18 casos (25%. A C. albicans foi a espécie mais prevalente (77,8% e conseqüentemente 22,2% foram não-albicans. Entre as não-albicans a espécie mais prevalente foi a C. glabrata (16,7% seguida pela C. parapsilosis (5,6%. Prurido e ardor foram os únicos sintomas relacionados significativamente com a presença de cândida. Foi observado que a C. glabrata, ao contrário da C. albicans, não causa corrimento clinicamente verificável ao exame ginecológico. Não foram verificadas associações de alguns fatores predisponentes (idade, escolaridade e uso de contraceptivos com a presença ou não de cândida. Conclusões: nossos resultados sugerem: a uma alta prevalência de Candida sp. entre as mulheres (25%; b que as espécies não-albicans desempenham um papel importante no meio vaginal; c que prurido e ardor são os sintomas mais comuns na presença de cândida e d que a C. glabrata não costuma causar corrimento vaginal ao exame ginecológico. Finalmente, é importante observar que nossos resultados são consistentes com o que a literatura internacional tem mostrado nos últimos anos.SUMMARY Purpose: to estimate the prevalence of Candida sp. and the distribution of its species in the vagina of women attended at a family planning Service. Methods: a cross-sectional study evaluating prospectively 72 nonpregnant women, with or without specific complaints. Samples were checked for the presence of yeast and vaginal pH. Data obtained by gynecologic examination were also recorded. Results: yeast belonging to the genus Candida was isolated from 18 (25% patients. The most prevalent species was C. albicans (77,8% and therefore, 22.2% were non-albicans species. The most prevalent among the non-albicans species was C. glabrata (16.7% followed by C. parapsilosis (5.6%. The symptoms most directly associated with Candida were itching and burning. Different from the symptoms directly associated with C. albicans infection, we observed that C. glabrata does not cause vaginal discharge. There was no positive association between predisponent factors such as age, education and contraceptive method used and the presence or absence of Candida. Conclusions: our results suggest: (i that there is a high prevalence of Candida species among women; (ii that non-albicans species play an important role in the vaginal medium; (iii that itching and burning are the most common symptoms in women with Candida, and (iv C. glabrata usually does not cause vaginal discharge. Finally, it is important to emphasize that our results are consistent with the present worldwide findings.

  13. Prevalência de cândida na flora vaginal de mulheres atendidas num serviço de planejamento familiar / Prevalence of candida in the vagina of women attended at a family planning service

    Scientific Electronic Library Online (English)

    Antônio, Aleixo Neto; Júnia Soares, Hamdan; Ressalla Castro, Souza.

    Full Text Available RESUMO Objetivo: avaliar a prevalência de Candida sp. e a distribuição de suas espécies na flora vaginal de mulheres numa clínica de planejamento familiar. Método: estudo transversal no qual se avaliaram prospectivamente 72 mulheres não-grávidas, com ou sem queixas específicas, sendo coletadas amost [...] ras de secreção vaginal para cultura de leveduras, efetuada a medição do pH vaginal e anotados dados de achados do exame ginecológico. Resultados: leveduras pertencentes ao gênero Candida foram encontradas em 18 casos (25%). A C. albicans foi a espécie mais prevalente (77,8%) e conseqüentemente 22,2% foram não-albicans. Entre as não-albicans a espécie mais prevalente foi a C. glabrata (16,7%) seguida pela C. parapsilosis (5,6%). Prurido e ardor foram os únicos sintomas relacionados significativamente com a presença de cândida. Foi observado que a C. glabrata, ao contrário da C. albicans, não causa corrimento clinicamente verificável ao exame ginecológico. Não foram verificadas associações de alguns fatores predisponentes (idade, escolaridade e uso de contraceptivos) com a presença ou não de cândida. Conclusões: nossos resultados sugerem: a) uma alta prevalência de Candida sp. entre as mulheres (25%); b) que as espécies não-albicans desempenham um papel importante no meio vaginal; c) que prurido e ardor são os sintomas mais comuns na presença de cândida e d) que a C. glabrata não costuma causar corrimento vaginal ao exame ginecológico. Finalmente, é importante observar que nossos resultados são consistentes com o que a literatura internacional tem mostrado nos últimos anos. Abstract in english SUMMARY Purpose: to estimate the prevalence of Candida sp. and the distribution of its species in the vagina of women attended at a family planning Service. Methods: a cross-sectional study evaluating prospectively 72 nonpregnant women, with or without specific complaints. Samples were checked for t [...] he presence of yeast and vaginal pH. Data obtained by gynecologic examination were also recorded. Results: yeast belonging to the genus Candida was isolated from 18 (25%) patients. The most prevalent species was C. albicans (77,8%) and therefore, 22.2% were non-albicans species. The most prevalent among the non-albicans species was C. glabrata (16.7%) followed by C. parapsilosis (5.6%). The symptoms most directly associated with Candida were itching and burning. Different from the symptoms directly associated with C. albicans infection, we observed that C. glabrata does not cause vaginal discharge. There was no positive association between predisponent factors such as age, education and contraceptive method used and the presence or absence of Candida. Conclusions: our results suggest: (i) that there is a high prevalence of Candida species among women; (ii) that non-albicans species play an important role in the vaginal medium; (iii) that itching and burning are the most common symptoms in women with Candida, and (iv) C. glabrata usually does not cause vaginal discharge. Finally, it is important to emphasize that our results are consistent with the present worldwide findings.

  14. Is there a subset of patients with recurrent cancer in the vagina who are not candidates for interstitial brachytherapy that can be treated with multichannel vaginal brachytherapy using graphic optimization?

    Science.gov (United States)

    Bylund, Kevin C.; Matloubieh, Ahmad; Mazloom, Ali; Gray, Alexander; Sidhu, Ravinder; Barrette, Lucille; Chen, Yuhchyau

    2015-01-01

    Purpose To evaluate recurrent vaginal cancer treated with vaginal brachytherapy (VBT) using graphic optimization in patients not amenable to surgery and interstitial brachytherapy (ISBT). Material and methods We retrospectively reviewed the records of 5 patients with recurrent cancer in the vagina that were deemed not to be good candidates for ISBT implant because of medical reasons. All patients received computed tomography/magnetic resonance imaging (CT/MRI) based evaluation in addition to a detailed clinical examination, and were noted to have recurrent nodules in the vagina with size ranging from 10-25 mm. Four of the 5 patients had recurrent disease in the vaginal apex, whereas one patient had recurrence in the lateral vaginal wall. Subsequently, all patients were treated with external beam radiation therapy (EBRT) followed by multichannel vaginal cylinder (MVC)-based VBT using graphic optimization for shaping the isodose to improve the clinical target volume (CTV) coverage, as well as to spare the organs at risk (OAR). The dose to the bladder and rectum with regard to 0.1 cc, 1 cc, and 2 cc were recorded. Results Median age of the patients was 78 years (range 58-86 years). Thickness of the lesions before VBT ranged from 6-15 mm. All patients were followed up with MRI at 3 months. All patients but one demonstrated complete clinical/ radiological response of the tumor. No patient had any grade III/IV toxicity at 24 months. Conclusions MVC-based VBT using graphic optimization is safe and yields favorable results if used judiciously.

  15. Citología y Análisis Morfométrico de las Células del Epitelio Vaginal Durante el Ciclo Estral en Ovejas de Pelo (Ovis aries) / Citology and Morphometric Analysis of Epithelial Cells from the Vagina of Hair Sheep Ewes (Ovis aries) During their Estrous Cycle

    Scientific Electronic Library Online (English)

    Neftali, Clemente Ovando; Agustín, Orihuela Trujillo; Fernando Iván, Flores Pérez; Virginio, Aguirre Flores.

    2013-09-01

    Full Text Available La citología vaginal puede usarse para caracterizar estados del ciclo reproductivo de la hembra. Sin embargo, no ha sido validada en ovinos de pelo, y ofrece resultados inexactos debido a interpretaciones subjetivas. El objetivo del presente trabajo es tipificar las características morfológicas y mo [...] rfométricas de las células epiteliales de la vagina durante el ciclo estral en ovinos de pelo. Cinco borregas Santa Cruz se sincronizaron con esponjas intravaginales. Desde el día del 1er celo posterior al retiro de la esponja y hasta el siguiente celo, se obtuvieron muestras diarias del epitelio vaginal de cada oveja, y se cuantificó el número de células parabasales, intermedias y superficiales, y se midió la longitud, perímetro y área de citoplasma y núcleo de cada una. Los resultados muestran que las células superficiales incrementan (P Abstract in english Vaginal cytology can be used to characterize stages of the reproductive cycle of the female. However, it has not been validated in hair sheep, and generates inaccurate results due to subjective interpretations. Thus, the purpose of the present work is to typify morphologic and morphometric character [...] istics of the epithelial cells from the vagina during the estrous cycle of hair sheep. Five Saint Croix ewes were synchronized with intravaginal sponges. Day zero of the cycle was considered the day of first estrus after sponge withdrawal. From this day until next estrus, samples from the vaginal epithelium were obtained daily from each ewe. The number of basal, intermediate and superficial cells was quantified, and length, perimeter, and area from cytoplasm and nucleus were obtained. The results show that the number of superficial cells increase (P

  16. MRI of the uterus, uterine cervix, and vagina: diagnostic performance of dynamic contrast-enhanced fast multiplanar gradient-echo imaging in comparison with fast spin-echo T2-weighted pulse imaging

    International Nuclear Information System (INIS)

    The aim of this study was to compare the diagnostic performance of contrast-enhanced fast multiplanar gradient-echo (GRE) and T2-weighted fast spin-echo (FSE) image sets in the assessment of uterus, cervix, and vagina. Fast (up to 20 contiguous sections in 23 s) multiplanar GRE and FSE images of 45 patients referred for imaging of the female pelvis were evaluated retrospectively with regard to overall image quality and the ability to detect normal anatomic structures, as well as lesion conspicuity. Results were compared with histologic findings (n = 29) or clinical follow-up. Furthermore, a quantitative assessment of contrast-to-noise ratios among normal uterine and cervical structures as well as uterine lesions was performed for both sequences. On GRE images, uterine and cervical differentiation was best seen on the image sets acquired 15 and 60 s following contrast enhancement and results were significantly better compared with delayed images (p 2 test, the difference in diagnostic performance between FSE and GRE revealed no significant deen FSE and GRE revealed no significant difference, whereas the combination of both techniques performed better than FSE imaging alone (p < 0.05). The presented data suggest that dynamic contrast-enhanced GRE imaging should be part of an MR examination of the female pelvis. Combined GRE and FSE imaging provide an excellent sensitivity in the assessment of uterine and vaginal pathologies. (orig.) (orig.)

  17. High-yield induction of uterine endometrial adenocarcinomas in Donryu rats by a single intra-uterine administration of N-ethyl-N'-nitro-N-nitrosoguanidine via the vagina.

    Science.gov (United States)

    Ando-Lu, J; Takahashi, M; Imai, S; Ishihara, R; Kitamura, T; Iijima, T; Takano, S; Nishiyama, K; Suzuki, K; Maekawa, A

    1994-08-01

    A total of 130 female Donryu rats (10-week-old) were divided into two groups; 80 animals in the experimental group were given a single intra-uterine administration of 20 mg/kg N-ethyl-N'-nitro-N-nitrosoguanidine (ENNG) dissolved in polyethylene glycol (PEG) via the vagina without laparotomy, and 50 animals in the control group received PEG alone in the same manner. Small numbers of animals in both groups were killed at 3, 6, 9 and 12 months after ENNG treatment for sequential histological and endocrinological examination, and at 12.5 experimental months (15 months of age) all survivors were killed. At the termination, endometrial adenocarcinomas were present in 49% of the experimental group, compared to 0% in the control group. Severe endometrial hyperplasias were also found only in the experimental group and sequential histological examination showed first appearance of hyperplasia at 6 months and adenocarcinoma at 9 months. No tumors other than uterine carcinomas were induced by ENNG and the carcinogen treatment did not affect the endocrine environment of rats, persistent estrus appearing at 6 months after the start and increasing with age in both groups. The estradiol-17 beta:progesterone (E:P) ratio was also increased after 6 months, with further elevation at 12 months to about 8 times higher than the level at 6 months. These results indicate that an increased E:P ratio might act as a promoter of development of endometrial proliferative lesions initiated by ENNG in this rat strain. The study indicates that the present simple method using Donryu rats provides a good animal model for endometrial adenocarcinoma development in women. PMID:7928623

  18. Congenital malformations of uterus and vagina

    International Nuclear Information System (INIS)

    The radiographic findings according to the classification of Buttram and Gibbons are described for HSG, ultrasound and MRI. The advantages and limitations of each method are discussed, and finally an algorithm for imaging is recommended. (orig.)

  19. Primary invasive squamous carcinoma of the vagina

    International Nuclear Information System (INIS)

    Forty-three cases of primary vaginal squamous cell cancer were treated at the University of Wisconsin Hospital between 1956 and 1971. These cases comprised of 1.2% of patients admitted to the University Hospital with female genital tract cancer. Evidence is presented to support a modification of the currently accepted FIGO staging system for vaginal carcinoma (Stage II disease). Radiation therapy using both external beam and brachyradium equivalents or interstitial implantation of suitable isotopes was an effective method for the treatment of patients having early and locally advanced invasive vaginal cancer. The 5-year absolute survival rate for the entire series was 37.2%. Absolute survival rate by modified FIGO clinical staging was 66% for Stages I and IIA, 31% for Stage IIB, 25% for Stage III, and 0% for Stage IV

  20. Caracterización de la microbiota levaduriforme residente en la vagina de perras en diferentes fases del ciclo estral Characterization of vaginal microbiotic yeasts of bitches in distinct stages of the oestrous cycle

    Directory of Open Access Journals (Sweden)

    M B Cleff

    2007-01-01

    Full Text Available Hongos levaduriformes son aislados frecuentemente de los animales domésticos y silvestres, siendo algunos comensales del tegumento y mucosas. Las levaduras son frecuentes en la mucosa vaginal de las mujeres, pero en perras son escasos los estudios referentes a la microbiota fúngica vaginal, sin conocerse su relación con el ciclo reproductivo. En este estudio se buscó aislar e identificar levaduras de la microbiota vaginal de perras, y establecer si hay alteración de la microbiota levaduriforme en las fases del ciclo reproductivo. Se analizaron 75 muestras de la vagina de 75 perras de los caniles particulares (Grupo I y 224 muestras de 14 perras experimentales (Grupo II. El ciclo estral fue determinado por citología vaginal y se registraron observaciones clínicas como sangrado, edema y pliegues de vulva. Las muestras fueron sometidas a examen directo y cultivos en Agar-Sabouraud dextrosa con cloranfenicol, a 37 ºC por 10 días. Las levaduras fueron clasificadas por macro y micromorfología, pruebas bioquímicas, tubo germinativo y microcultivo. De las 75 muestras del grupo I, el aislamiento fue 33,3% (n = 25; las muestras fueron obtenidas en las fases de proestro 56,3%, estro 16,7%, diestro 66,7% y anestro 20,5%, respectivamente. De las 224 muestras del grupo II se aislaron levaduras en 147 (65,6%: en proestro 61,9%, estro 71,9%, diestro 82,7% y anestro 57,1%, respectivamente. Las levaduras fueron identificadas como Candida spp, Malassezia pachydermatis y Rhodoturola spp. Los resultados sugieren que estas levaduras forman parte de la microbiota vaginal de perras sanas y sus frecuencias se alteran en las fases del ciclo reproductivo.Yeasts are commensal organisms frequently isolated from the skin and mucous membranes of domestic and wild mammals. Although yeasts are frequently isolated from women’s vaginal mucus, similar studies in canine are rare, therefore their behaviour during the canine oestrous cycle is unknown. The purpose of this study was to isolate yeasts from the vaginal microbiota of bitches and to evaluate their behaviour in different stages of the oestrous cycle. We examined 75 samples of mucus from the vaginal cavity of 75 domestic bitches and 224 samples from 14 experimental bitches. The stages of the oestrous cycle were characterized through vaginal cytology and clinical observation of bleeding, vulvar oedema and pucker. Samples were examined visually, and also cultured in Sabouraud dextrose agar with chloranphenicol, at 37 ºC for 10 days. The yeasts were classified according to their macro and micro morphology, biochemical tests, germination tube and micro culture. Yeasts were isolated from 25 (33.3% samples from domestic females. Among the samples collected during proestrous, oestrous, diestrous and anestrous, 56.3% 16.7% 66.7% and 20.5% were positive, respectively. Yeasts were isolated from 147 (65.6% samples from experimental bitches. Among the samples collected during proestrous, oestrous, diestrous and anestrous, positive samples represented 61.9%, 71.9%, 82.7%, and 57.1%, respectively. The identified species were Candida spp, M. pachydermatis and Rhodotorula spp, which are commonly present in the vaginal mucus microbiota of healthy bitches and their frequency changes with the different stages of the oestrous cycle.

  1. Caracterización de la microbiota levaduriforme residente en la vagina de perras en diferentes fases del ciclo estral / Characterization of vaginal microbiotic yeasts of bitches in distinct stages of the oestrous cycle

    Scientific Electronic Library Online (English)

    M B, Cleff; M O, Xavier; A A, Martins; R, Santin; M C A, Meireles.

    Full Text Available Hongos levaduriformes son aislados frecuentemente de los animales domésticos y silvestres, siendo algunos comensales del tegumento y mucosas. Las levaduras son frecuentes en la mucosa vaginal de las mujeres, pero en perras son escasos los estudios referentes a la microbiota fúngica vaginal, sin cono [...] cerse su relación con el ciclo reproductivo. En este estudio se buscó aislar e identificar levaduras de la microbiota vaginal de perras, y establecer si hay alteración de la microbiota levaduriforme en las fases del ciclo reproductivo. Se analizaron 75 muestras de la vagina de 75 perras de los caniles particulares (Grupo I) y 224 muestras de 14 perras experimentales (Grupo II). El ciclo estral fue determinado por citología vaginal y se registraron observaciones clínicas como sangrado, edema y pliegues de vulva. Las muestras fueron sometidas a examen directo y cultivos en Agar-Sabouraud dextrosa con cloranfenicol, a 37 ºC por 10 días. Las levaduras fueron clasificadas por macro y micromorfología, pruebas bioquímicas, tubo germinativo y microcultivo. De las 75 muestras del grupo I, el aislamiento fue 33,3% (n = 25); las muestras fueron obtenidas en las fases de proestro 56,3%, estro 16,7%, diestro 66,7% y anestro 20,5%, respectivamente. De las 224 muestras del grupo II se aislaron levaduras en 147 (65,6%): en proestro 61,9%, estro 71,9%, diestro 82,7% y anestro 57,1%, respectivamente. Las levaduras fueron identificadas como Candida spp, Malassezia pachydermatis y Rhodoturola spp. Los resultados sugieren que estas levaduras forman parte de la microbiota vaginal de perras sanas y sus frecuencias se alteran en las fases del ciclo reproductivo. Abstract in english Yeasts are commensal organisms frequently isolated from the skin and mucous membranes of domestic and wild mammals. Although yeasts are frequently isolated from women’s vaginal mucus, similar studies in canine are rare, therefore their behaviour during the canine oestrous cycle is unknown. The purpo [...] se of this study was to isolate yeasts from the vaginal microbiota of bitches and to evaluate their behaviour in different stages of the oestrous cycle. We examined 75 samples of mucus from the vaginal cavity of 75 domestic bitches and 224 samples from 14 experimental bitches. The stages of the oestrous cycle were characterized through vaginal cytology and clinical observation of bleeding, vulvar oedema and pucker. Samples were examined visually, and also cultured in Sabouraud dextrose agar with chloranphenicol, at 37 ºC for 10 days. The yeasts were classified according to their macro and micro morphology, biochemical tests, germination tube and micro culture. Yeasts were isolated from 25 (33.3%) samples from domestic females. Among the samples collected during proestrous, oestrous, diestrous and anestrous, 56.3% 16.7% 66.7% and 20.5% were positive, respectively. Yeasts were isolated from 147 (65.6%) samples from experimental bitches. Among the samples collected during proestrous, oestrous, diestrous and anestrous, positive samples represented 61.9%, 71.9%, 82.7%, and 57.1%, respectively. The identified species were Candida spp, M. pachydermatis and Rhodotorula spp, which are commonly present in the vaginal mucus microbiota of healthy bitches and their frequency changes with the different stages of the oestrous cycle.

  2. Pregnancy Complications: Bleeding and Spotting from the Vagina

    Science.gov (United States)

    ... for you to feel emotionally ready to be pregnant again. Everyone responds differently to a miscarriage. Only you will know when you are ready to try to get pregnant again. Are gallstones common during pregnancy? Not common, ...

  3. Uterus and vagina. TNM classification of malignant tumours

    International Nuclear Information System (INIS)

    Cervix uteri and Corpus uteri were amongst the first sites to be classified by the TNM system. The ''League of Nations'' Stages for carcinoma of the cervix have been used with minor modifications for nearly fifty years and because these are accepted by the Federation Internationale de Gynecologie et d'Obstetrique (FIGO), the TNM categories have been defined to correspond to the FIGO stages. Some amendments have been made in collaboration with FIGO and the classifications now published will remain unchanged until at least 1986

  4. Radiotherapeutic management of carcinomas of the vagina and vulva

    International Nuclear Information System (INIS)

    Purpose: To review important basic information regarding vaginal and vulvar carcinomas, including etiology, epidemiology, anatomy, pathology, spread patterns, presentation and work-up and staging. In addition, treatment concepts strategies, and radiotherapeutic techniques will be reviewed and discussed. Discussion: Vaginal carcinoma is rare, making up only 1-2% of gynecologic malignancies. However, the predominant role of radiotherapy (RT) is its management results in a significant number of patients referred to radiation oncology. Treatment and outcomes vary substantially according to stage. Important issues for consideration include the respective roles of external beam RT, brachytherapy, and surgery, intracavitary vs. interstitial brachytherapy, dose rate considerations, combined modality therapy, and management of non-squamous cell histologies. Vulvar carcinoma is similarly uncommon, comprising only 3-5% of gynecologic malignancies. Radiotherapy has a number of established roles in the management of this disease including adjuvant therapy, as part of combined modality treatment for advanced disease, salvage therapy, palliative treatment, and less often, as primary management. These issues will be discussed along with technical factors important in radiotherapeutic management. Finally, relevant literature will be reviewed with an emphasis of completed Gynecologic Oncology Group Trials

  5. Late effects of ionizing radiations on vulva, vagina and uterus

    International Nuclear Information System (INIS)

    Reporting and scoring complications after radiotherapy of gynaecological cancers is difficult because of the variety of treatment techniques involved. Use of an international classification is necessary to compare results obtained in series of patients treated in different institutions. An international group of experts designed in the early nineties the so-called French-Italian glossary. This classification of late effects is now completed with the new LENT SOMA scales. This paper contains details of these late changes, including their pathophysiology, clinical syndromes, potential treatment, and prevention. (authors)

  6. [Biopharmaceutic and technological investigation of vagina suppositories containing brilliant green].

    Science.gov (United States)

    Dzhavakhiia, M Sh; Churadze, L I; Iavich, P A

    2008-05-01

    The vaginal suppository composition, containing 0, 05, 0, 1 and 0, 5 of drug substance is presented. The release of drug substance was investigated. The influence of a number of the factors on the degree of release was investigated. Cocoa oil, confectionery fat and three different types of emulgator were used. According to gained results the average release degree was 73-76%, which is sufficient for effective action of a preparation. The technological parameters of suppositories including the temperature melting and hardening are determined. All parameters were at an acceptable level. The optimum composition of suppositories was determined. The optimal composition of suppositories was determined (base, emulgator, the content of active substance, mass of the suppository. The investigation proved the effectiveness of the preparation. PMID:18560037

  7. Malla de polipropileno multifilamento con autofijación de silicona exteriorizada a vagina / Multifilament polypropylene mesh with exteriorization of the silicone anchorage to the vagina

    Scientific Electronic Library Online (English)

    Vicente, Solà Dalenz; Jack, Pardo Schanz; Paolo, Ricci Arriola; Enrique, Guiloff Fische.

    1099-11-01

    Full Text Available Objetivo: Describir un caso de falla de en una cirugía de cinta suburetral para corrección de la incontinencia de orina de esfuerzo con sistema Safyre VS (vaginal-suprapubic approach) multifilamento, a los 34 meses de buena evolución. Método: Descripción del caso y su resolución. Resultado: Se prese [...] ntó con descenso del sistema de sujeción lateral y erosión de la mucosa vaginal con exposición de la cinta e infección. Se retiró con gran facilidad el sistema de anclaje de silicona que se encontraba suelto y se colocó una nueva cinta suburetral con sistema TVT-O, recuperando la continencia antes lograda. Conclusiones: La malla sintéticas de los sistemas de corrección con cinta suburetral para la incontinencia de orina de esfuerzo, deben ser de polipropileno, macroporo y monofilamento. Estas características permiten una mejor biointegración, reduciendo teóricamente el número de complicaciones (erosión de pared vaginal, exposición y sobreinfección). Respecto a la falla del sistema de sujeción de silicona, ya que no se han informado otros casos en los estudios de seguimiento entre 12 y 36 meses (media 14 y 18 meses), sólo los estudios que contemplen seguimientos a largo plazo permitirán decir si se trata de un caso aislado o aparecerán otros. Abstract in english Objectives: To describe the failure of one case of suburethral tape for the correction of the stress urinary incontinence with the multifilament Sapphire VS (vaginal-suprapubic approach) system after 34 months of good outcome. Methods: Description of the case and its resolution. Results: The patient [...] presented with a descent of the lateral fixation and erosion of the vaginal mucosa with exposure of the mesh and infection. The silicone fixation system, which was loose, was retrieved very easily and a new suburethral mesh with the system TVT-O was inserted; the patient recovered continence as before. Conclusions: Synthetic mesh in the suburethral tape systems for stress urinary incontinence correction should be polypropylene, macropore and monofilament. These characteristics enable better bio integration, theoretically reducing the number of complications (vaginal wall erosion, exposition and over infection). In relation with the failure of the silicone fixation system, no other casers have been reported in follow-up studies between 12 and 36 months (mean follow-up 14 and 18 months), so hat studies with long-term follow-up will be able to determine if this is an isolated case or there will be others.

  8. The Microbiota of the Vagina and Its Influence on Women’s Health and Disease

    Science.gov (United States)

    Martin, David H.

    2011-01-01

    Explorations of the vaginal microbiota (VMB) began over 150 years ago. Using light microscopy and bacterial cultures the concept of normal versus abnormal microbiotain women began to emerge. The latter became known by the term “bacterial vaginosis” or BV. BV microbiota is dominated by Gardnerella vaginalis and includes a number of anaerobic organisms. In contrast normal flora is dominated various Lactobacilli. BV microbiota is associated with vaginal discharge, poor pregnancy outcomes, pelvic inflammatory disease, post-operative wound infections, and endometritis following elective abortions. Additionally, BV flora predisposes women to infection by HIV as well as other STDs. Application of molecular techniques over the last decade has significantly advanced our understanding of the VMB. It is far more complex than previously recognized and is comprised of many previously unknown organisms in addition to those already identified by culture. Analyses using high-throughput sequencing techniques have revealed unique microbial communities not previously recognized within the older, established vaginal flora categories. These new findings will inform the design of future clinical investigations of the role of the VMB in health and disease. PMID:22143133

  9. Laparoscopic management of fallopian tube prolapse masquerading as adenocarcinoma of the vagina in a hysterectomized woman

    Directory of Open Access Journals (Sweden)

    Kucuk Mustafa

    2002-01-01

    Full Text Available Abstract Background Fallopian tube prolapse as a complication of abdominal hysterectomy is a rare occurrence. A case with fallopian tube prolapse was managed by a combined vaginal and laparoscopic approach and description of the operative technique is presented. Case presentation A 39-year-old woman with vaginal prolapse of the fallopian tube after total abdominal hysterectomy presented with an incorrect diagnosis of adenocarcinoma of the vaginal apex. The prolapsed tube and cystic ovary were removed by vaginal and laparoscopic approach. The postoperative course went well. Conclusions Early or late fallopian tube prolapse can occur after total abdominal hysterectomy and vaginal hysterectomy. Symptoms consist of persistent blood loss or leukorrhea, dyspareunia and chronic pelvic pain. Vaginal removal of prolapsed tube with laparoscopic surgery may be a suitable treatment. The abdominal or vaginal approach used in surgical correction of prolapsed tubes must be decided in each case according to the patient's individual characteristics.

  10. Fine structure of the male reproductive ducts, vagina and seminal receptacle of Cyathocephalus truncatus (Cestoda: Spathebothriidea).

    Czech Academy of Sciences Publication Activity Database

    Poddubnaya, L. G.; Mackiewicz, J. S.; Bru?anská, Magdaléna; dezfuli, B. S.

    2005-01-01

    Ro?. 52, ?. 3 (2005), s. 241-250. ISSN 0015-5683 R&D Projects: GA ?R GA206/03/1317 Grant ostatní: Russian Foundation of Fundamental Research(RU) 05-0448250 Institutional research plan: CEZ:AV0Z60220518 Keywords : ultrastructure * reproductive organs * Cestoda Subject RIV: EA - Cell Biology Impact factor: 1.138, year: 2005

  11. The influence of radium therapie on the yeast contamination of the vagina

    International Nuclear Information System (INIS)

    Before the beginning of radium therapy a vaginal yeast contamination of 9,7% was found of 113 patients with various genital carcinomas. However, the incidence of vaginal yeast contamination increased suddenly to 30,9% under the contac irradiation therapy with radium. The radiation effect of radium is not sufficient for a 'selfsterilisation' of the radium-carrier in the case of yeast contamination. Therefore, a chemic desinfection of the radium-carriers is principly necessary. The significance is discussed and the recommendation is made that routine mycological supervision be carried out on all patients with gynaecological carcinomas and appropriate antimycotic therapy initiated where necessary. (orig.)

  12. Unexpected finding of an intact distal vagina in an infant with mixed gonadal dysgenesis

    OpenAIRE

    Cabrera, Susanne M.; Alvarez, Rudy; Kaefer, Martin N.; Eugster, Erica A.; Nebesio, Todd D.

    2011-01-01

    Mixed gonadal dysgenesis (MGD) is a form of sex chromosome disorder of sex development with large phenotypic variability. Patients with MGD typically have asymmetric and ambiguous genitalia with a combination of Müllerian and Wolffian duct derivatives. Prenatal androgen exposure results in variable degrees of phallic enlargement and a urogenital sinus. Here, we report an infant with ambiguous genitalia due to MGD. Despite marked evidence of prenatal androgen exposure, there was a completely ...

  13. Importance of brachytherapy technique in the management of primary carcinoma of the vagina

    International Nuclear Information System (INIS)

    Primary vaginal carcinoma is a rare malignancy. There is little information regarding the optimal treatment. Management has primarily been with external-beam radiation therapy and brachytherapy. This paper examines the importance of brachytherapy and the significance of its techniques in the treatment of this disease. Brachytherapy plays an important part in the management of primary vaginal carcinoma. External-beam radiation therapy alone is not an adequate treatment for this disease. For stages II and III disease, there is a trend toward improved disease-free survival with the use of a temporary interstitial implant compared to an intracavitary application

  14. Adenocarcinoma of vagina: combined surgery and radiation with preservation of genital function

    International Nuclear Information System (INIS)

    A report is given of a patient treated at Memorial Hospital, New York City, by external and fractionated intravaginal radiation given after a surgical procedure that consisted of local excision of tumor, pretreatment laparotomy, and lateral ovarian transposition. The treatment plan was based on the observations that there was no evidence of local or distant spread and that the ovaries could be moved to positions where radiation exposure would not terminate their activity. The patient has survived over six years and is without evidence of recurrence

  15. Isolated epithelioid trophoblastic tumor of the vagina: a case report and review of the literature

    OpenAIRE

    Zhao J.; Xiang Y; Zhao D.; Ren T; Feng F; Wan X

    2013-01-01

    Jing Zhao,1 Yang Xiang,1 Dachun Zhao,2 Tong Ren,1 Fengzhi Feng,1 Xirun Wan1 1Department of Obstetrics and Gynecology, 2Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China Abstract: An epithelioid trophoblastic tumor (ETT) is a rare trophoblastic tumor originating from chorionic-type intermediate trophoblasts. Vaginal involvement in ETT in the form of isolated lesions has n...

  16. Functional significance of muscarinic receptor expression within the proximal and distal rat vagina

    OpenAIRE

    Basha, Maureen; Labelle, Edward F.; Northington, Gina M.; Wang, Tanchun; Wein, Alan J.; Chacko, Samuel

    2009-01-01

    Information regarding the role of cholinergic nerves in mediating vaginal smooth muscle contraction is sparse, and in vitro studies of the effects of muscarinic agonists on vaginal smooth muscle are discrepant. The goal of this study was to determine the expression of muscarinic receptors in the vaginal wall of the rat. In addition, we sought to determine the effect of the muscarinic receptor agonist carbachol on contractility and inositol phosphate production of the proximal and distal rat v...

  17. Radiotherapy of primary carcinoma of the vagina: management and results of different therapy schemes

    International Nuclear Information System (INIS)

    Three hundred and sixty-two cases of primary vaginal carcinoma were treated at the Irradiation Department of the University Clinic for Obstetrics and Gynecology, Vienna, from 1950 to 1977. As the method of choice an individually dosed, fractioned, and protracted radium-telecobalt therapy was employed. Comparing the last period analyzed (1971-1977) with another period 20 years earlier (1951-1956), a marked increase of advanced stages and older patients can be observed. These changes are reflected in the 5-year remission rate: in the total population it was 39.8%, as compared to 32% for the period from 1971 to 1977. For a group of 99 patients, who were treated between 1971 and 1977, the therapeutic effect of different therapy schemes is reported. The benefit of teletherapy is remarkable for advanced states, whereas for stages I and II an intrauterine application may be of importance. The complication rate amounted to 8% recto- or vesicovaginal fistulas and 41% and 43% cystitis and proctitis. The central importance of gynecological screening, especially for older women, is emphasized

  18. Air in vagina: significance in the staging of uterine cervical carcinoma

    International Nuclear Information System (INIS)

    To evaluate the significance of vaginal air seen on CT scan in preoperative staging of uterine cervical carcinoma. A comparison was made between CT findings of vaginal fir and true vaginal involvement status in 85 patients with uterine cervical carcinoma. CT findings were analyzed in terms of the presence or absence of vaginal air, number of CT slices in which vaginal air was seen, shape of vaginal air, and relation of vaginal air to cervical mass. Vaginal air was present in 35 patients and was absent in 50. Although the mere presence of vaginal air or multiplicity of CT slices showing vaginal air did not signify the presence of vaginal involvement, vaginal air with irregular margin or vaginal air adjacent to uterine cervical mass was suggestive of vaginal involvement. These observation of vaginal air in interpreting CT may be helpful in the preoperative staging of uterine cervical carcinoma

  19. Didelphic uterus with imperforate unilateral vagina and ipsilateral renal agenesis: Magnetic resonance

    International Nuclear Information System (INIS)

    We present two cases of didelphic uterus with the clinical appearance of a pelvic mass produced by the hematometra-hematocolpos retained by an imperforate unilateral hemivagina. In both cases, this anomaly was accompanied by ipsilateral renal agenesis. We basically review the diagnosis of this disorder, focusing on magnetic resonance as the technique of choice. (Author) 10 refs

  20. Iterstitial gamma-therapy of recurrences and metastases of uterine and rectal cancer to the vagina

    International Nuclear Information System (INIS)

    A technique of interstitial radiation therapy for locally disseminated vaginal recurrences and metastases that occOr after the use of various therapeutic methods for uterine and rectal cancer is devised. Indications and coUnterindications to interstitial radiation therapy with 60Co as an independent method or the main therapeutic component in combined or multimodality treatment, were determined. Methods of the topometric and dosimetric planning of treat-- ment, methods of needle administration and fixation by the system of manual afterloading were developed. Interstitial radiation therapy was given to 22 patients with a complete tumor regression in 17 of them. Interstitial radiation therapy is recommended as a method of choice for the therapy of vaginal recurrences and metastases

  1. High-dose rate brachytherapy (HDRB for primary or recurrent cancer in the vagina

    Directory of Open Access Journals (Sweden)

    Kelley Joseph L

    2008-02-01

    Full Text Available Abstract Purpose The purpose of this study was to evaluate the efficacy of HDR brachytherapy for primary or recurrent vaginal cancer. Methods Between the years 2000 to 2006, 18 patients with primary or recurrent vaginal cancer were treated with brachytherapy (HDRB. Six patients had primary vaginal cancer (stage II to IVA while 12 were treated for isolated vaginal recurrence (primary cervix = 4, vulva = 1 and endometrium = 7. Five patients had previous pelvic radiation therapy. All except one patient received external beam radiation therapy to a median dose of 45 Gy (range 31.2–55.8 Gy. The HDRB was intracavitary using a vaginal cylinder in 5 patients and interstitial using a modified Syed-Nesblett template in 13 patients. The dose of interstitial brachytherapy was 18.75 Gy in 5 fractions delivered twice daily. The median follow-up was 18 months (range 6–66 months. Results Complete response (CR was achieved in all but one patient (94%. Of these 17 patients achieving a CR, 1 had local recurrence and 3 had systemic recurrence at a median time of 6 months (range 6–22 months. The 2-year actuarial local control and cause-specific survival for the entire group were 88% and 82.5%, respectively. In subset analysis, the crude local control was 100% for primary vaginal cancer, 100% for the group with recurrence without any prior radiation and 67% for group with recurrence and prior radiation therapy. Two patients had late grade 3 or higher morbidity (rectovaginal fistula in one patient and chronic vaginal ulcer resulting in bleeding in one patient. Both these patients had prior radiation therapy. Conclusion Our small series suggests that HDRB is efficacious for primary or recurrent vaginal cancer. Patients treated with primary disease and those with recurrent disease without prior irradiation have the greatest benefit from HDRB in this setting. The salvage rate for patients with prior radiation therapy is lower with a higher risk of significant complications. Additional patients and follow-up are ongoing to determine the long-term efficacy of this approach.

  2. Sheila Jeffreys: The Industrial Vagina. The Political Economy of the Global Sex Trade. London: Routledge 2008.

    Directory of Open Access Journals (Sweden)

    Susanne Hofmann

    2010-02-01

    Full Text Available Sheila Jeffreys analysiert die Prozesse, die zu einer Industrialisierung und Globalisierung von Prostitution im späten 20. und 21. Jahrhundert geführt haben. Hauptverantwortlich für die gegenwärtige Diskursverschiebung um Prostitution ist für Jeffreys zum einen die sexuelle Revolution der 1970er Jahre und zum anderen die massive Finanzierung von Unterstützer/-innen der Sexarbeiterinnen zur HIV-Prävention in den 1980ern. Jeffreys legt wie in früheren Arbeiten ihre radikal-feministische Position dar und fordert eine Abschaffung der Prostitution. In ihrer Abrechnung mit dem liberalen feministischen Diskurs, für den eine Unterstützung von Sexarbeiterinnen prioritär ist, ignoriert sie die Widersprüchlichkeiten und Komplexitäten der gelebten Realitäten. An vielen Stellen ihres Buches bekräftigt Jeffreys stereotypische Männlichkeitsvorstellungen, was durch einen Blick über den Tellerrand des ihr vertrauten wissenschaftlichen Bezugsrahmens hätte vermieden werden können.

  3. Sheila Jeffreys: The Industrial Vagina. The Political Economy of the Global Sex Trade. London: Routledge 2008.

    Directory of Open Access Journals (Sweden)

    Susanne Hofmann

    2010-03-01

    Full Text Available Sheila Jeffreys analysiert die Prozesse, die zu einer Industrialisierung und Globalisierung von Prostitution im späten 20. und 21. Jahrhundert geführt haben. Hauptverantwortlich für die gegenwärtige Diskursverschiebung um Prostitution ist für Jeffreys zum einen die sexuelle Revolution der 1970er Jahre und zum anderen die massive Finanzierung von Unterstützer/-innen der Sexarbeiterinnen zur HIV-Prävention in den 1980ern. Jeffreys legt wie in früheren Arbeiten ihre radikal-feministische Position dar und fordert eine Abschaffung der Prostitution. In ihrer Abrechnung mit dem liberalen feministischen Diskurs, für den eine Unterstützung von Sexarbeiterinnen prioritär ist, ignoriert sie die Widersprüchlichkeiten und Komplexitäten der gelebten Realitäten. An vielen Stellen ihres Buches bekräftigt Jeffreys stereotypische Männlichkeitsvorstellungen, was durch einen Blick über den Tellerrand des ihr vertrauten wissenschaftlichen Bezugsrahmens hätte vermieden werden können.Sheila Jeffreys analyzes the processes that led to the industrialization and globalization of prostitution in the late 20th and 21th centuries. Jeffreys considers those primary factors responsible for the current shift in discourse on prostitution, which can be attributed to the sexual revolution of the 1970s on the one hand, and to massive financing of HIV prevention in the 1980s by sex worker supporters on the other. As in earlier studies, Jeffreys presents readers with her radical-feminist position and demands prostitution be abolished. In her confrontation with liberal-feminist discourse, in which the support of sex workers takes priority, she ignores the inconsistencies and complexities of real lived experience. At many points throughout her book, Jeffreys affirms stereotypical male conceptions, which could have been avoided had she looked beyond the theoretical frame of reference that makes up her comfort zone.

  4. Primary T-Cell Non-Hodgkin Lymphoma of the Vagina

    Science.gov (United States)

    Herraiz, J. L.; Llueca, A.; Maazouzi, Y.; Piquer, D.; Palmeiro, A.; Calpe, E.

    2015-01-01

    The primary vaginal T-cell non-Hodgkin lymphoma is a rare form of lymphoma. Most of the previously published cases were about B-cell non-Hodgkin lymphomas. We present the case of a vaginal mass in an 82-year-old patient presenting vaginal bleeding. The results of the immunohistological studies of the mass revealed the presence of a cytotoxic T-cell non-Hodgkin lymphoma, which is the least common subtype. PMID:26101677

  5. Radiotherapy for carcinoma of the vagina. Immunocytochemical and cytofluorometric analysis of prognostic factors

    Energy Technology Data Exchange (ETDEWEB)

    Blecharz, P. [Maria Sklodowska-Curie Memorial Institute, Krakow (Poland). Dept. of Gynecological Oncology; Reinfuss, M.; Jakubowicz, J. [Maria Sklodowska-Curie Memorial Institute, Krakow (Poland). Dept. of Radiation Oncology; Rys, J. [Maria Sklodowska-Curie Memorial Institute, Krakow (Poland). Dept. of Tumor Pathology Oncology; Skotnicki, P.; Wysocki, W. [Maria Sklodowska-Curie Memorial Institute, Krakow (Poland). Dept. of Oncological Surgery

    2013-05-15

    Background and purpose: The aim of this study was to assess the potential prognostic factors in patients with primary invasive vaginal carcinoma (PIVC) treated with radical irradiation. Patients and methods: The analysis was performed on 77 patients with PIVC treated between 1985 and 2005 in the Maria Sklodowska-Curie Memorial Institute of Oncology, Cancer Center in Krakow. A total of 36 patients (46.8 %) survived 5 years with no evidence of disease (NED). The following groups of factors were assessed for potential prognostic value: population-based (age), clinical (Karnofsky Performance Score [KPS], hemoglobin level, primary location of the vaginal lesion, macroscopic type, length of the involved vaginal wall, FIGO stage), microscopic (microscopic type, grade, mitotic index, presence of atypical mitoses, lymphatic vessels invasion, lymphocytes/plasmocytes infiltration, focal necrosis, VAIN-3), immunohistochemical (protein p53 expression, MIB-1 index), cytofluorometric (ploidity, index DI, S-phase fraction, proliferation index SG2M) factors. Results: Significantly better 5-year NED was observed in patients: < 60 years, KPS {<=} 80, FIGO stage I and II, grade G1-2, MIB-1 index < 70, S-phase fraction < 10, and proliferation index < 25. Independent factors for better prognosis in the multivariate Cox analysis were age < 60 years, FIGO stage I or II, and MIB-1 index < 70. Conclusion: Independent prognostic factors in the radically irradiated PIVC patients were as follows: age, FIGO stage, MIB-1 index. (orig.)

  6. Radiotherapy for carcinoma of the vagina. Immunocytochemical and cytofluorometric analysis of prognostic factors

    International Nuclear Information System (INIS)

    Background and purpose: The aim of this study was to assess the potential prognostic factors in patients with primary invasive vaginal carcinoma (PIVC) treated with radical irradiation. Patients and methods: The analysis was performed on 77 patients with PIVC treated between 1985 and 2005 in the Maria Sklodowska-Curie Memorial Institute of Oncology, Cancer Center in Krakow. A total of 36 patients (46.8 %) survived 5 years with no evidence of disease (NED). The following groups of factors were assessed for potential prognostic value: population-based (age), clinical (Karnofsky Performance Score [KPS], hemoglobin level, primary location of the vaginal lesion, macroscopic type, length of the involved vaginal wall, FIGO stage), microscopic (microscopic type, grade, mitotic index, presence of atypical mitoses, lymphatic vessels invasion, lymphocytes/plasmocytes infiltration, focal necrosis, VAIN-3), immunohistochemical (protein p53 expression, MIB-1 index), cytofluorometric (ploidity, index DI, S-phase fraction, proliferation index SG2M) factors. Results: Significantly better 5-year NED was observed in patients: < 60 years, KPS ? 80, FIGO stage I and II, grade G1-2, MIB-1 index < 70, S-phase fraction < 10, and proliferation index < 25. Independent factors for better prognosis in the multivariate Cox analysis were age < 60 years, FIGO stage I or II, and MIB-1 index < 70. Conclusion: Independent prognostic factors in the radically irradiated PIVC patients were as follows: radiated PIVC patients were as follows: age, FIGO stage, MIB-1 index. (orig.)

  7. Supportive tissues of the vagina with special reference to a fibrous skeleton in the perineum: A review

    OpenAIRE

    Hiromasa Sasaki; Nobuyuki Hinata; Tetsuji Kurokawa; Gen Murakami

    2014-01-01

    With the aid of immunohistochemistry, the present review attempts to demonstrate the composite fibers and nerve topographical anatomy in the vaginal supportive tissues. Along the tendinous arch of the pelvic fasciae, distal parts of the pelvic plexus extend antero-inferiorly and issue nerves to the internal anal sphincter as well as the cavernous tissues. At the attachment of the levator ani muscle to the rectum, smooth muscles in the endopelvic fascia lining the lev...

  8. A multi-platform metabolomics approach identifies novel biomarkers associated with bacterial diversity in the human vagina

    OpenAIRE

    Mcmillan, Amy; Rulisa, Stephen; Sumarah, Mark; Macklaim, Jean M.; Renaud, Justin; Bisanz, Jordan; Gloor, Gregory B.; Reid, Gregor

    2015-01-01

    Bacterial vaginosis (BV) increases transmission of HIV, enhances the risk of preterm labour, and its associated malodour impacts the quality of life for many women. Clinical diagnosis primarily relies on microscopy to presumptively detect a loss of lactobacilli and acquisition of anaerobes. This diagnostic does not reflect the microbiota composition accurately as lactobacilli can assume different morphotypes, and assigning BV associated morphotypes to specific organisms is c...

  9. Biomarkers of semen in the vagina: applications in clinical trials of contraception and prevention of sexually transmitted pathogens including HIV.

    Science.gov (United States)

    Mauck, Christine K; Doncel, Gustavo F

    2007-06-01

    Biomarkers of vaginal exposure to semen, long used in forensic medicine, are now becoming important in the development of vaginal microbicides to prevent HIV/STIs and the development of contraceptives. Semen biomarkers could help evaluate the safety of a new physical or chemical barrier, give preliminary indication of the effectiveness of physical barriers such as diaphragms or condoms, and provide information on unprotected intercourse among participants in a clinical trial who have been advised to use condoms. Candidate biomarkers of semen exposure fall into two broad categories: (1) biomarkers of seminal plasma, among which prostate-specific antigen (PSA) is the best characterized; and (2) biomarkers of spermatozoa and other cells present in semen. This paper, authored by a working group of investigators performing research in the field of semen biomarkers, summarizes the characteristics of an ideal semen biomarker, reviews preclinical and clinical data on existing and potential biomarkers, and outlines the steps that should be carried out to develop an improved biomarker of semen exposure. PMID:17519146

  10. Sodium Tetradecyl Sulphate Direct Intralesional Sclerotherapy of Venous Malformations of the Vulva and Vagina: Report of Five Cases

    International Nuclear Information System (INIS)

    We report five cases of female patients affected by symptomatic focal external genital venous malformations treated with percutaneous direct intralesional injection of sodium tetradecyl sulphate (STS). All patients were referred because of discomfort and pain when sexual intercourse was attempted. Direct sclerotherapy with 3% STS was performed on a day-hospital basis with the patient under local anesthesia. Complete resolution of the symptoms was achieved in all cases. No major adverse effects were reported. Direct intralesional sclerotherapy with STS may be considered a safe and effective method for the treatment of female external genital malformation without the necessity of general anesthesia for pain control.

  11. Comparative study vagina mould/ fletcher applicator in MRI guided pulsed rate brachytherapy in patients reached by an uterine cervix carcinoma

    International Nuclear Information System (INIS)

    This study began in february 2009 and included until today ten patients. twenty patients are planned. The analysis of preliminary results show a much higher tolerance for the vaginal cast device. The dosimetry data were the object of a preliminary study that seems demonstrate an equivalence of the both modalities, with differences concerning the doses to critical organs; The definitive result swill be presented with the data including the twenty planned patients. (N.C.)

  12. General Information about Vaginal Cancer

    Science.gov (United States)

    ... in which malignant (cancer) cells form in the vagina. The vagina is the canal leading from the ... Pain when urinating . Constipation . Tests that examine the vagina and other organs in the pelvis are used ...

  13. Robot-Assisted Gynecologic Oncology Surgery

    Medline Plus

    Full Text Available ... the junction between the cervix and the upper vagina. And I'm trying to -- sometimes it's really ... to start a colpotomy, which is opening the vagina, separating the cervix from the vagina. 00:27: ...

  14. Vaginal itching and discharge - child

    Science.gov (United States)

    ... redness, and swelling of the skin of the vagina and the surrounding area ( vulva ) is a common ... softeners, creams, ointments, and sprays may irritate the vagina or the skin around the vagina. Vaginal yeast ...

  15. Vaginal Anomalies: Congenital Vaginal Obstruction

    Science.gov (United States)

    ... is usually due to incomplete canalization of the vagina during development. Either of these can result in hydrocolpos, an abnormal swelling of the vagina, or hydrometrocolpos, abnormal swelling of both the vagina ...

  16. Vaginal and Vulvar Cancer

    Science.gov (United States)

    Vagina Fallopian Tubes Ovaries Uterus Cervix Vulva Vaginal and Vulvar Cancer Get the Facts About Gynecologic Cancer ... body parts later. When cancer starts in the vagina, it is called vaginal cancer. The vagina, also ...

  17. What Is Vaginal Cancer?

    Science.gov (United States)

    ... about vaginal cancer? What is vaginal cancer? The vagina The vagina is a 3- to 4-inch ( ... refers only to cancers that start in the vagina, also known as primary vaginal cancers. Last Medical ...

  18. Role of HOXA7 to HOXA13 and PBX1 genes in various forms of MRKH syndrome (congenital absence of uterus and vagina

    Directory of Open Access Journals (Sweden)

    Pellerin Isabelle

    2006-03-01

    Full Text Available Abstract The Mayer-Rokitansky-Küster-Hauser (MRKH syndrome refers to the congenital absence or severe hypoplasia of the female genital tract, often described as uterovaginal aplasia which is the prime feature of the syndrome. It is the second cause of primary amenorrhea after gonadal dysgenesis and occurs in ~1 in 4500 women. Aetiology of this syndrome remains poorly understood. Frequent association of other malformations with the MRKH syndrome, involving kidneys, skeleton and ears, suggests the involvement of major developmental genes such as those of the HOX family. Indeed mammalian HOX genes are well known for their crucial role during embryogenesis, particularly in axial skeleton, hindbrain and limb development. More recently, their involvement in organogenesis has been demonstrated notably during urogenital differentiation. Although null mutations of HOX genes in animal models do not lead to MRKH-like phenotypes, dominant mutations in their coding sequences or aberrant expression due to mutated regulatory regions could well account for it. Sequence analysis of coding regions of HOX candidate genes and of PBX1, a likely HOX cofactor during Müllerian duct differentiation and kidney morphogenesis, did not reveal any mutation in patients showing various forms of MRKH syndrome. This tends to show that HOX genes are not involved in MRKH syndrome. However it does not exclude that other mechanisms leading to HOX dysfunction may account for the syndrome.

  19. Carcinoma epidermoide no queratinizante de células grandes y pequeñas en vagina / Large and small cells non-keratinizing epidermoid vaginal carcinoma

    Scientific Electronic Library Online (English)

    Ofelia, Masó Anaya; María Elena, Morales Larramendi; Dolores, Díaz Pérez; Esperanza, Dager Dager; Gloria Adelaida, Bolaños Diego.

    2012-03-01

    Full Text Available Se presentan 5 casos clínicos de pacientes atendidas en la consulta de patología de cuello del Hospital Provincial Ginecoobstétrico "Mariana Grajales Coello" de Santiago de Cuba por presentar sangrado vaginal, dolor en bajo vientre, leucorrea y lesiones vaginales. El estudio anatomopatológico confir [...] mó el diagnóstico de carcinoma de células escamosas o epidermoide. Abstract in english Five case reports of patients who were assisted at the cervix Pathology Department from "Mariana Grajales Coello" Provincial Gynecological Obstetrical Hospital in Santiago de Cuba due to vaginal bleeding, low abdominal pain, leukorrhea and vaginal injuries are presented. The pathological study confi [...] rmed the diagnosis of squamous or epidermoid cells carcinoma.

  20. Caracterización de la microbiota levaduriforme residente en la vagina de perras en diferentes fases del ciclo estral Characterization of vaginal microbiotic yeasts of bitches in distinct stages of the oestrous cycle

    OpenAIRE

    Cleff, M. B.; Xavier, M. O.; Martins, A. A.; Santin, R.; Meireles, M. C. A.

    2007-01-01

    Hongos levaduriformes son aislados frecuentemente de los animales domésticos y silvestres, siendo algunos comensales del tegumento y mucosas. Las levaduras son frecuentes en la mucosa vaginal de las mujeres, pero en perras son escasos los estudios referentes a la microbiota fúngica vaginal, sin conocerse su relación con el ciclo reproductivo. En este estudio se buscó aislar e identificar levaduras de la microbiota vaginal de perras, y establecer si hay alteración de la microbiota levadur...

  1. First two cases of primary carcinoma of the vagina successfully treated with concurrent weekly carboplatin plus paclitaxel, external beam radiotherapy and high-dose-rate interstitial brachytherapy: a case report and published work review.

    Science.gov (United States)

    Mabuchi, Seiji; Kawano, Mahiru; Isohashi, Fumiaki; Kuroda, Hiromasa; Sasano, Tomoyuki; Kimura, Tadashi

    2015-01-01

    Vaginal carcinoma is rare, accounting for only 2% of all gynecological malignancies. Due to a lack of prospective randomized studies, the role of concurrent chemoradiotherapy in the treatment of primary vaginal carcinoma remains unclear. We report the first two cases of primary vaginal carcinoma successfully treated with a regimen involving concurrent weekly carboplatin plus paclitaxel, external beam radiotherapy and high-dose-rate interstitial brachytherapy. These cases strongly indicate that definitive chemoradiation involving carboplatin plus paclitaxel may be a reasonable treatment for primary vaginal carcinoma. PMID:25227150

  2. Healthy Sexuality

    Medline Plus

    Full Text Available ... from the walls of the vagina. The vaginal muscles relax, causing the vagina to lengthen and widen. ... causing it to rise and stiffen. The smooth muscles of the scrotum contract, the skin of the ...

  3. Robot-Assisted Gynecologic Oncology Surgery

    Medline Plus

    Full Text Available ... Now we're doing what we call skeletonizing, opening up this peritoneum and trying to isolate the ... are going to start a colpotomy, which is opening the vagina, separating the cervix from the vagina. ...

  4. Stages of Urethral Cancer

    Science.gov (United States)

    ... remove the urethra, the bladder, and the vagina . Plastic surgery may be done to rebuild the vagina. Partial ... penis surrounding the urethra where cancer has spread. Plastic surgery may be done to rebuild the penis. Radical ...

  5. Ovarian Cancer Screening

    Science.gov (United States)

    ... A pelvic exam is an exam of the vagina , cervix , uterus , fallopian tubes , ovaries , and rectum . The ... lubricated , gloved fingers of one hand into the vagina and the other hand is placed over the ...

  6. Fibroid Tumors

    Medline Plus

    Full Text Available ... the lower part of uterus that joins the vagina. There are two main layers in the body ... or those which push on the bowel, the vagina, or pelvic wall may also make bowel movements, ...

  7. Surgical Tutorial of a Robotic-Assisted Anterior Pelvic Exenteration

    Medline Plus

    Full Text Available ... anterior portion of the cervix and the anterior vagina and it invading into the posterior bladder. To ... remove the bladder, the anterior part of the vagina, the cervix and surrounding tissues as well last ...

  8. Ultrasound -- Pelvis

    Medline Plus

    Full Text Available ... involves the insertion of the transducer into the vagina after you empty your bladder. The tip of ... amount of gel, and then inserted into the vagina. Only two to three inches of the transducer ...

  9. Robotic-Assisted Hysterectomy

    Medline Plus

    Full Text Available ... it lets me make my vaginotomy access the vagina much more easily, and as long as I ... actually don't remove the uterus from the vagina, you remove the uterus from an incision in ...

  10. Stages of Vaginal Cancer

    Science.gov (United States)

    ... out if cancer cells have spread within the vagina or to other parts of the body. The ... found in tissue lining the inside of the vagina. These abnormal cells are not cancer. Vaginal intraepithelial ...

  11. Pelvic Organ Prolapse

    Science.gov (United States)

    ... coughing, sneezing, or laughing). Rectal prolapse into the vagina (rectocele) The rectum drops down and creates a ... here) or rectal prolapse. Rectal prolapse into the vagina (rectocele) The rectum can drop downward, creating a ...

  12. Pelvic Organ Prolapse

    Medline Plus

    Full Text Available ... coughing, sneezing, or laughing). Rectal prolapse into the vagina (rectocele) The rectum drops down and creates a ... here) or rectal prolapse. Rectal prolapse into the vagina (rectocele) The rectum can drop downward, creating a ...

  13. Sexual Problems

    Medline Plus

    Full Text Available ... no pleasurable sexual sensations in her clitoris or vagina. Male erectile disorder, or ED, is the inability ... intercourse. Pain may occur with entry into the vagina or as deep pain. Both psychological and physical ...

  14. Estradiol Topical

    Science.gov (United States)

    ... a medication that is applied topically to the vagina. Estradiol is in a class of medications called ... swelling, redness, burning, irritation, or itching of the vagina vaginal discharge Some side effects can be serious. ...

  15. Types of Hymens

    Science.gov (United States)

    ... thin membrane that surrounds the opening to the vagina. Hymens can come in different shapes. The most ... menstrual blood to flow out of a girl’s vagina. Imperforate hymen : An imperforate hymen can be diagnosed ...

  16. Bacterial vaginosis - aftercare

    Science.gov (United States)

    ... BV) is a type of vaginal infection. The vagina normally contains both healthy bacteria and unhealthy bacteria. ... when you urinate Itching inside and outside the vagina You also may not have any symptoms.

  17. Nystatin

    Science.gov (United States)

    ... to treat fungal infections of the skin, mouth, vagina, and intestinal tract. Fungal medicines will not work ... and vaginal cream to be inserted into the vagina; and in powder, ointment, and cream to be ...

  18. Robotic-Assisted Hysterectomy for Endometrial Cancer

    Medline Plus

    Full Text Available ... we have time, when we sew on the vagina we’re using just a traditional suture material. ... is no worry about cautery damage to the vagina. There isn’t significant heat within the vaginal ...

  19. Laparo-Endoscopic Single-Site (LESS) Procedure

    Medline Plus

    Full Text Available ... great results that having to go through the vagina or through the stomach, it just doesn't ... a hysterectomy, and everything is extracted through the vagina -- or the chole and anti-reflux operation. Before ...

  20. Laparoscopic Supracervical Hysterectomy

    Medline Plus

    Full Text Available ... end of the uterus which attaches to the vagina and empties into the vaginal area. We discussed ... in place, you support the top of the vagina better. And we have…we believe that we ...

  1. Clotrimazole

    Science.gov (United States)

    ... is used to treat yeast infections of the vagina, mouth, and skin such as athlete's foot, jock ... and vaginal cream to be inserted into the vagina. Clotrimazole is usually used five times a day ...

  2. Postpartum Period: Discomfort and Recovery

    Medline Plus

    Full Text Available ... postpartum bleeding? Postpartum bleeding is bleeding from the vagina after giving birth. It’s normal. However, heavy bleeding ( ... you may have heavy bleeding. Tearing : If your vagina or cervix (opening to the uterus that sits ...

  3. Vaginal Infections

    Science.gov (United States)

    ... have pain, itching, or other symptoms around your vagina, don’t try to treat them yourself. Don’ ... include itching, burning, pain in or around your vagina , or a problem with your vaginal discharge (fluid). ...

  4. Endometriosis

    Medline Plus

    Full Text Available ... has some tenderness at the top of her vagina and recommends further testing. She has a vaginal ... grow into other organs including the intestines, bladder, vagina and ureters, which are the tubes from the ...

  5. General Information about Cervical Cancer

    Science.gov (United States)

    ... The cervix leads from the uterus to the vagina (birth canal). Anatomy of the female reproductive system. ... include the uterus, ovaries, fallopian tubes, cervix, and vagina. The uterus has a muscular outer layer called ...

  6. Vaginal Anomalies: Fusion and Duplication

    Science.gov (United States)

    ... certain organs — such as the uterus, cervix, and vagina — is not a welcome turn of events. What ... that evolve into the fallopian tubes , uterus and vagina in females. They come together during the ninth ...

  7. Robotic-Assisted Laparoscopic Sacrocolpopexy for Vaginal Vault Prolapse

    Medline Plus

    Full Text Available ... surgically correct vaginal vault prolapse by resupporting the vagina to the sacrum using a polypropylene mesh. Dr. ... they were not at all attached to the vagina. I'm going to orient you to the ...

  8. Butoconazole Vaginal Cream

    Science.gov (United States)

    ... is used to treat yeast infections of the vagina.This medication is sometimes prescribed for other uses; ... comes as a cream to insert into the vagina. It is usually used daily at bedtime. Follow ...

  9. Terconazole Vaginal Cream, Vaginal Suppositories

    Science.gov (United States)

    ... to treat fungal and yeast infections of the vagina.This medication is sometimes prescribed for other uses; ... a cream and suppository to insert into the vagina. It is usually used daily at bedtime for ...

  10. Rectocele

    Science.gov (United States)

    ... the rectum into the back wall of the vagina. The tissue between the rectum and the vagina is known as the rectovaginal septum and this ... the small intestine (enterocele), can bulge into the vagina, leading to similar symptoms as rectocele. WHAT CAUSES ...

  11. 21 CFR 884.4520 - Obstetric-gynecologic general manual instrument.

    Science.gov (United States)

    2010-04-01

    ...expose and illuminate the interior of the vagina. (3) A metal vaginal speculum is...instrument used to expose the interior of the vagina. (4) An umbilical scissors is a...introduce dressing into the uterus or vagina. (7) A vaginal applicator is an...

  12. In Vitro Activity of Nifuratel on Vaginal Bacteria: Could It Be a Good Candidate for the Treatment of Bacterial Vaginosis??

    Science.gov (United States)

    Togni, Giuseppe; Battini, Valeria; Bulgheroni, Anna; Mailland, Federico; Caserini, Maurizio; Mendling, Werner

    2011-01-01

    Bacterial vaginosis is characterized by a shift of the physiological flora to a diverse spectrum of bacteria, where Gardnerella vaginalis and Atopobium vaginae are the most important markers. In this study, the antimicrobial activity of nifuratel against G. vaginalis, A. vaginae, and lactobacilli was compared with that of the two currently used antibiotics metronidazole and clindamycin. Results suggest that nifuratel has a better spectrum of activity, being highly active against G. vaginalis and A. vaginae without affecting lactobacilli. PMID:21321147

  13. In vitro activity of nifuratel on vaginal bacteria: could it be a good candidate for the treatment of bacterial vaginosis?

    Science.gov (United States)

    Togni, Giuseppe; Battini, Valeria; Bulgheroni, Anna; Mailland, Federico; Caserini, Maurizio; Mendling, Werner

    2011-05-01

    Bacterial vaginosis is characterized by a shift of the physiological flora to a diverse spectrum of bacteria, where Gardnerella vaginalis and Atopobium vaginae are the most important markers. In this study, the antimicrobial activity of nifuratel against G. vaginalis, A. vaginae, and lactobacilli was compared with that of the two currently used antibiotics metronidazole and clindamycin. Results suggest that nifuratel has a better spectrum of activity, being highly active against G. vaginalis and A. vaginae without affecting lactobacilli. PMID:21321147

  14. Development of vesicovaginal fistula caused by vaginal adenosis: A case report

    OpenAIRE

    Ryoichi Tanaka; Miwa Suzuki; Motoki Matsuura; Shutaro Habata; Takahiro Suzuki5; Tasuku Mariya; Tsuyoshi Saito

    2013-01-01

    Introduction: Vaginal adenosis is one of the rare diseases of the vagina, and almost all patients are asymptomatic. We report a case of spontaneous vaginal adenosis, which caused vesicovaginal fistula. Case Presentation: Our patient was a 25-year-old Japanese woman. She was admitted to our hospital, and her chief complaint was continuous urine flow from the vagina. We found a tumor with a vesicovaginal fistula in her vagina. Subsequent cytological analysis of vaginal smears showed a normal v...

  15. The normal microflora of the female rabbit's genital tract.

    OpenAIRE

    Jacques, M.; Olson, M. E.; Crichlow, A. M.; Osborne, A. D.; Costerton, J. W.

    1986-01-01

    Microorganisms associated with the vagina, cervix and uterus of rabbits were isolated and identified. The predominant microorganisms isolated from the vaginas and cervices were coagulase-negative staphylococci, micrococci, and nonfermentative bacilli. Coagulase-negative staphylococci were isolated frequently, but in small numbers, from the uteri. The pH of the rabbit vagina was found to be near neutrality. Our data indicate that the genital flora of female rabbits is relatively simple, regard...

  16. Labial flap vaginoplasty with sacrospinous fixation

    OpenAIRE

    Chandrashekar Murthy; Kiran Ashok; Susheel Kumar Kalal

    2010-01-01

    We present a case of congenital absence of Vagina which was treated by reconstruction of the vagina using vascular labial flaps. Furthermore, we anchored the neo-vagina to the Sacro-spinous ligament on either side. The aim of the attachment to the sacro-spinous ligament is to provide a durable apical support and to give an immediate, good vaginal length. Various techniques have been described for the construction of Neo-vagina. Except for sigmoid vaginoplasty, most other procedures are associ...

  17. Colpopéxia transcoccígea con malla de polipropileno con orificios facilitadores de la integración en la corrección del prolapso de la pared posterior de la vagina: resultados anatómicos y funcionales / Transcoccigeal colpopexy with polyprolylene mesh with helper orifices for the treatment of posterior vaginal wall prolapse: anatomical and functional results

    Scientific Electronic Library Online (English)

    Vitor, Pagotto; Paulo, Palma; Cassio, Riccetto; Miguel, Bigozzi.

    2009-04-01

    Full Text Available Objetivo: La creación de neoligamentos útero- sacros, según lo descripto por Petros, con el uso de malla sintética de polipropileno permite la corrección anatómica del prolapso posterior en los tres niveles propuestos por DeLancey. El objetivo de este estudio es evaluar los resultados anatómicos y f [...] uncionales de este método en la corrección del POP posterior. Pacientes y método: Desde diciembre del 2004 a marzo del 2007, 34 mujeres con edad media de 63 años fueron sometidas al procedimiento, siendo rectoceles grado III o mayores. El seguimento mínimo fué de 13 meses. Los puntos de fijación fueron el músculo íleococcígeo y el ligamento sacroespinoso. Técnica: Luego de la incisión de la mucosa de la pared vaginal posterior, la fosa ísquio-rectal es disecada. Dos pequeñas incisiones son hechas 3 cm lateral y 3 cm inferior al ano. La aguja se inserta verticalmente en dirección a la espina isquiática, guiado por el dedo indicador del cirujano hasta el ligamento sacroespinoso, 2 cm medialmente, evitando a lesión del canal de Alcock. Los brazos de la malla son conectados a la punta de la aguja, traccionando posteriormente de las agujas. No se realiza la correción sitio específica. El exceso de malla es recortado y esta se fija próxima al cuerpo perineal, quedando de esa forma extendida sobre la pared vaginal posterior. La mucosa vaginal se cierra en forma habitual. Resultados: Con el 94,7% de cura y recurrencia del 5,3%, no hubo lesión nerviosa, visceral o vascular. Cinco (14,7%) pacientes tuvieron exposición de la malla de menos de 1 cm² y fueron tratadas conservadoramente sin impacto en los resultados. Dos de las 17 sexualmente activas (11,8%) presentaron dispareunia transitoria, siendo prolongada en 1 solo caso (5,9%) Conclusión: Este procedimiento mínimamente invasivo es una alternativa atractiva para la reconstrucción anatómica y funcional de los defectos posteriores y apicales. Abstract in english Objective: The creation of neo utero-sacral neoligaments, decribed by Petros, evolved into a new procedure allowing for the anatomical reconstruction of the three levels proposed by DeLancey. The aim of this study is evaluate the anatomical and functional outcomes of this minimally invasive procedur [...] e. Patients and method: From December 2004 to March 2007, a total of 34 patients with posterior defect grade III or higher underwent this procedure. The minimum follow up was 13 months Mean age was 63 years. The site of fixation was the Sacrospinous ligament. Surgical technique: The ischiorectal fossa is dissected. Next two small skin incisions are made 3 cm lateral and inferior to the center of the anus. A proper needle is introduced, vertically towards the sacrospinal ligament at the level of the ischial spine, guided by the surgeon index finger, 2 cm medially avoiding the Alcok canal. The armpit of the mesh is connected to the tip of the needle and brought to the perineal region. No site specific correction is made. Results: The cure rate was 94,7% and recurrence rate was 5,3%. No visceral, nerurovascular injuries were observed. The mesh exposure rate (less than 1 cm²) was (14.7%) and all patients were treated conservatively with no impact on the outcome. There were transient dyspareunia in 2 (11.8%) of the 17 sexually active patient and persistent in 1 case (5.9%). Conclusions: This procedure is an attractive minimally invasive alternative for the anatomical and functional reconstruction of the posterior and apical defects.

  18. Comparative study vagina mould/ fletcher applicator in MRI guided pulsed rate brachytherapy in patients reached by an uterine cervix carcinoma; Etude comparative moule vaginal/applicateur de fletcher en curietherapie de debit pulse guide par IRM chez les patientes atteintes d'un cancer du col uterin

    Energy Technology Data Exchange (ETDEWEB)

    Francois, G.; Dumas, I.; Mazeron, R.; Verezesan, O.; Monnier, L.; Vieillot, S.; Gensse, M.C.; Haie-Meder, C. [Institut Gustave-Roussy, 94 - Villejuif (France)

    2009-10-15

    This study began in february 2009 and included until today ten patients. twenty patients are planned. The analysis of preliminary results show a much higher tolerance for the vaginal cast device. The dosimetry data were the object of a preliminary study that seems demonstrate an equivalence of the both modalities, with differences concerning the doses to critical organs; The definitive result swill be presented with the data including the twenty planned patients. (N.C.)

  19. Wnt family genes and their modulation in the ovary-independent and persistent vaginal epithelial cell proliferation and keratinization induced by neonatal diethylstilbestrol exposure in mice

    International Nuclear Information System (INIS)

    Proliferation and differentiation of cells in female reproductive organs, the oviduct, uterus and vagina, are regulated by endogenous estrogen. In utero exposure to a synthetic estrogen, diethylstilbestrol (DES), induces vaginal clear-cell adenocarcinoma in humans. In mice, perinatal exposure to DES results in abnormalities such as polyovular follicles, uterine circular muscle disorganization and persistent vaginal epithelial cell proliferation. We reported the persistent gene expression change such as interleukin-1 (IL-1) related genes, insulin-like growth factor-I (IGF-I) and its downstream signaling in the mouse vagina exposed neonatally to DES. In this study, we found persistent up-regulation of Wnt4 and persistent down-regulation of Wnt11 in the vagina of mice exposed neonatally to DES and estrogen receptor ? specific ligand. Also Wnt4 expression in vagina is correlated to the stratification of epithelial cells with the superficial keratinization of vagina, but not epithelial cell stratification only.

  20. Vaginoplasty with a Pudendal-Thigh Flap in Intersexuals

    Directory of Open Access Journals (Sweden)

    Nakatsuka,Mikiya

    2008-12-01

    Full Text Available We treated 2 different types of intersexual patients who underwent a vaginoplasty with the pudendal-thigh flap. One was a female with testicular feminization syndrome for whom we reconstructed the total vagina with a pudendal-thigh flap, and the other was a female with an adrenogenital syndrome for whom we enlarged the introitus of the vagina with the same approach. There were no complications such as a flap necrosis. In addition, there was no stricture of the neo-vagina and no urinary problem.

  1. Rectal occurrence of Mobiluncus species.

    OpenAIRE

    Halle?n, A.; Pa?hlson, C.; Forsum, U.

    1988-01-01

    The simultaneous occurrence of Mobiluncus spp in the vagina and rectum was studied in women attending a sexually transmitted diseases (STD) department. Of 43 women with bacterial vaginosis (BV), 32 had Mobiluncus spp in the vagina and 23 in the rectum. In 20 women the same Mobiluncus species was found concomitantly in the vagina and the rectum. Mobiluncus spp were found in the rectum only in two women with BV, one with candidal vaginitis, and one healthy woman. In a treatment study of 23 wome...

  2. Vaginoplasty with a Pudendal-Thigh Flap in Intersexuals

    OpenAIRE

    Nakatsuka, Mikiya; Kimata, Yoshihiro; Hasegawa, Kenjiro; Yamashita, Shuji; Sugiyama, Narushi; Namba, Yuzaburo

    2008-01-01

    We treated 2 different types of intersexual patients who underwent a vaginoplasty with the pudendal-thigh flap. One was a female with testicular feminization syndrome for whom we reconstructed the total vagina with a pudendal-thigh flap, and the other was a female with an adrenogenital syndrome for whom we enlarged the introitus of the vagina with the same approach. There were no complications such as a flap necrosis. In addition, there was no stricture of the neo-vagina and no urinary problem.

  3. Robot-Assisted Gynecologic Surgery

    Medline Plus

    Full Text Available ... t o leave another hole into the pelvis via the vagina, right? And that’s that little space ... and procedures that right now are not done via robotics. Fantastic stuff. I want to say that ...

  4. Robotic-Assisted Hysterectomy

    Medline Plus

    Full Text Available ... beginning of the surgeon's learning curve. Ultimately the goal is to have this be if it's something ... ll be able to get that safely. My goal is to not enter the vagina here, it's ...

  5. Laparo-Endoscopic Single-Site (LESS) Procedure

    Medline Plus

    Full Text Available ... a chole and a hysterectomy, and everything is extracted through the vagina -- or the chole and anti- ... in. The idea simply is to not have dye (inaudible). But there's no reason that cholangiography can' ...

  6. Robotic-Assisted Laparoscopic Sacrocolpopexy for Vaginal Vault Prolapse

    Medline Plus

    Full Text Available ... of the vasculature. Middle sacral vessels line the space as well as a number of venous plexuses, ... reasons. One would be difficulty dissecting the presacral space, difficulty suturing the mesh to the vagina and ...

  7. Serotonin localization in the turkey vaginal but not sperm storage tubule epithelia.

    Science.gov (United States)

    Bakst, M R; Akuffo, V

    2008-02-01

    Elucidating the cellular and molecular mechanisms regulating sperm selection and transport in the vagina of the hen had been the focus of a limited amount of research over the past decade. New observations indicate the presence of nonneuron endocrine cells in the epithelia lining the lumina of the turkey hen vagina and uterovaginal junction. Although no cells in the vagina or uterovaginal junction surface epithelia exhibited argentaffin staining, typical of cells containing neurosecretory granules, cells restricted to the vaginal and uterovaginal junction but not the sperm storage tubule epithelia were immunoreactive positive to serotonin. We speculate that if released into the vaginal lumen and submucosa, serotonin could augment cilia and sperm tail beat frequencies and facilitate smooth muscle contraction, respectively. If this is the response to sperm at insemination, it would represent the first evidence of a local control mechanism responding to sperm in the turkey vagina. PMID:18212381

  8. Robotic-Assisted Laparoscopic Sacrocolpopexy for Vaginal Vault Prolapse

    Medline Plus

    Full Text Available ... able to get really good tissue dissection and planes, and I think the blood loss is pretty ... posterior vagina and were able to get a plane. The bladder had been adherent over the apex ...

  9. Robotic-Assisted Hysterectomy

    Medline Plus

    Full Text Available ... access the vagina much more easily, and as long as I stay above where I've transected ... Another question we received by email is, "How long is the recovery time compared to the traditional ...

  10. Robotic-Assisted Hysterectomy

    Medline Plus

    Full Text Available ... much less, and I think that makes a big difference for recovery for these patients. 00:32: ... may have better luck. It looks kind of big for her vagina. Sorry, Dr. Tulikangas. 00:37: ...

  11. Healthy Sexuality

    Medline Plus

    Full Text Available ... the stomach to breasts and neck develops. During orgasm, also called the climax, there are strong rhythmic ... the pelvic floor, the vagina, and uterus. After orgasm, this process may be repeated or the body ...

  12. Vaginal Yeast Infection

    Science.gov (United States)

    ... of a fungus called Candida albicans in the vagina. Candida is yeast, which is a type of fungus. ... using these products. For updated information about the treatment for vaginal yeast infections, read the Centers for Disease Control ...

  13. Fluconazole

    Science.gov (United States)

    Fluconazole is used to treat fungal infections, including yeast infections of the vagina, mouth, throat, esophagus (tube ... chest and waist), lungs, blood, and other organs. Fluconazole is also used to treat meningitis (infection of ...

  14. Staying Healthy and Safe at Work

    Science.gov (United States)

    ... page It's been added to your dashboard . Staying healthy and safe at work Most working women can ... from your vagina . Last reviewed June 2010 Staying healthy at work Wear gloves or a mask if ...

  15. Robot-Assisted Gynecologic Oncology Surgery

    Medline Plus

    Full Text Available ... difficult to work on because everything is all compressed. So weight itself can be misleading. I'd ... the vagina, because we're going to lose air and we're going to lose our visibility ...

  16. Endometriosis

    Medline Plus

    Full Text Available ... the top of her vagina and recommends further testing. She has a vaginal ultrasound that shows a ... A change in the function of the immune system has been one potential theory. No one is ...

  17. Ospemifene

    Science.gov (United States)

    ... around the vagina that can cause painful sexual intercourse. Ospemifene is in a class of medications called ... symptoms of menopause that can cause pain during intercourse but does not cure it. Continue to take ...

  18. Trichomoniasis

    Science.gov (United States)

    ... an infected partner, either through penis-to-vagina intercourse or vulva-to-vulva contact. The parasite cannot ... Women may have these symptoms: Discomfort with intercourse ... Vaginal itching Vulvar itching or swelling of the labia Vaginal ...

  19. Robot-Assisted Gynecologic Oncology Surgery

    Medline Plus

    Full Text Available ... rim of the VCare manipulator, and that helps guide me as a place to separate the vagina ... the procedure, and that's what I use to guide dissection to separate the cervix from the upper ...

  20. Epispadias

    Science.gov (United States)

    ... a congenital condition called epispadias can produce a penis or vagina that not only performs inefficiently, but ... a small dimple on the tip of the penis above the normal opening or with girls, it ...

  1. Vaginal yeast infection

    Science.gov (United States)

    Yeast infection - vagina; Vaginal candidiasis; Monilial vaginitis ... Most women have a vaginal yeast infection at some time. Candida albicans is a common type of fungus. It is often found in small amounts in the ...

  2. General Information About Uterine Sarcoma

    Science.gov (United States)

    ... uterus. The uterus is part of the female reproductive system . The uterus is the hollow, pear-shaped organ ... to the vagina . Enlarge Anatomy of the female reproductive system. The organs in the female reproductive system include ...

  3. Treatment Options by Stage (Uterine Sarcoma)

    Science.gov (United States)

    ... uterus. The uterus is part of the female reproductive system . The uterus is the hollow, pear-shaped organ ... to the vagina . Enlarge Anatomy of the female reproductive system. The organs in the female reproductive system include ...

  4. If I Had - Bowel Control Issues

    Medline Plus

    Full Text Available ... cause damage to the pelvic floor or the anal sphincter. Some patients are left after childbirth with an opening, called a fistula, between the bowel and the vagina, which means ...

  5. Postpartum Period: Discomfort and Recovery

    Medline Plus

    Full Text Available ... Bacteria also can enter your breast through the opening to milk ducts in your nipple. Signs of ... heavy bleeding. Tearing : If your vagina or cervix (opening to the uterus that sits on top of ...

  6. Healthy Sexuality

    Medline Plus

    Full Text Available ... or her sexuality. Let’s talk about how a woman’s body responds to sexual stimulation. During sexual arousal, blood flow increases to a woman’s genitals. Her vagina is lubricated by secretions from ...

  7. Intrauterine Devices

    Science.gov (United States)

    ... is removed and there is a chance of miscarriage. Journal of Midwifery & Women’s Health • www.jmwh.org ... her vagina Which IUD Should I Choose? The copper IUD (ParaGard;Figure 1) may be best for ...

  8. What Are the Treatments for Endometriosis?

    Science.gov (United States)

    ... the vagina and guided by ultrasound. The collected eggs are placed in a dish for fertilization with a man's sperm. The fertilized cells are then placed in an incubator, a machine that keeps them warm and allows ...

  9. Surgical Tutorial of a Robotic-Assisted Anterior Pelvic Exenteration

    Medline Plus

    Full Text Available ... to you by Intuitive Surgical. During the program, it’s easy for you to learn about the procedure. ... of the cervix and the anterior vagina and it invading into the posterior bladder. To make matters ...

  10. Vaginal atresia with transverse septum in a cat

    International Nuclear Information System (INIS)

    A six and half-year-old nulliparous mixed breed cat which had the complaints of vomiting, abdominal distention and depression was presented to the Veterinary Teaching Hospital of Osaka Prefecture University. She was suspected of pyometra by clinical signs and tests. By laparotomy, it was clarified that both uterine horns and vagina showed distension by the accumulation of secretions, and the vagina ended blindly leaving a tough connective tissue at the border between cranial and caudal part of the vagina. Postoperative contrast-radiograph of the remaining vagina proved it had no persistence of the hymen. From these findings, the condition was diagnosed as a feline atresia vaginalis with the transverse vaginal septum which is caused by the embryonic failure of canalization of the paramesonephric duct between the end of the Mullerian duct and the urogenital sinus

  11. Sexual Problems

    Medline Plus

    Full Text Available ... may be due to many factors, including physical, psychological, medical conditions, or medications. Men with male orgasmic ... into the vagina or as deep pain. Both psychological and physical factors can contribute to the condition. ...

  12. Healthy Sexuality

    Medline Plus

    Full Text Available ... also build intimacy in relationships and be a source of immense pleasure and satisfaction. Sex also has ... the lips of the genitals) become engorged and open, revealing the opening to the vagina. The uterus ...

  13. Surgery for Pre-Cancers and Cancers of the Cervix

    Science.gov (United States)

    ... in the vagina and on the cervix. This kills the abnormal cells by freezing them. Cryosurgery is ... remove all the cancer. General or epidural (regional) anesthesia is used for this operation. Radical hysterectomy: For ...

  14. Urethrovaginal Fistula in a 5-Year-Old Girl

    Science.gov (United States)

    Coulibaly, Noël; Sangaré, Ibrahima Séga

    2015-01-01

    Urethral fistulas are rare in girls. They occur most of the time during trauma. The case presented here is an iatrogenic fistula. The treatment was simple and consisted of a simple dissection and suture of urethra and vagina.

  15. Review of Vaginitis

    OpenAIRE

    Faro, Sebastian

    1993-01-01

    Adisruption of the dynamic equilibrium of the healthy vagina may have significant sequelae, leading to chronic or serious conditions. Therefore, all cases of vaginitis should be accurately diagnosed and appropriately treated.

  16. Intraperitoneal leech: A rare complication of leech bite

    OpenAIRE

    Saha, Manoj; Nagi, Sedengulie

    2011-01-01

    An intraperitoneal leech, which entered through vagina and uterus in a 2-year-old girl is reported. The child presented with intraperitoneal hemorrhage and shock. A leech inside the peritoneal cavity has never been reported in the literature.

  17. Hysteroscopic Sterilization

    Science.gov (United States)

    ... higher risk that it will be an ectopic pregnancy . Ectopic pregnancy can be a medical emergency. • In rare ... the uterus at the top of the vagina. Ectopic Pregnancy: A pregnancy in which the fertilized egg begins ...

  18. Long-Acting Reversible Contraception (LARC): IUD and Implant

    Science.gov (United States)

    ... a higher chance that it will be an ectopic pregnancy . What is the birth control implant? The birth ... the uterus at the top of the vagina. Ectopic Pregnancy: A pregnancy in which the fertilized egg begins ...

  19. Robotic-Assisted Hysterectomy for Endometrial Cancer

    Medline Plus

    Full Text Available ... the Koh ring. This Koh ring diffuses the heat so there is no worry about cautery damage to the vagina. There isn’t significant heat within the vaginal tissues, so again, this is ...

  20. Healthy Sexuality

    Medline Plus

    Full Text Available ... responds to sexual stimulation. During sexual arousal, blood flow increases to a woman’s genitals. Her vagina is ... are drawn up toward the abdomen. Meanwhile, seminal fluid collects in the prostatic urethra and the bulbourethral ...

  1. Choosing a Fertility Specialist

    Medline Plus

    Full Text Available ... more sensitive than a home pregnancy test that checks your urine. The blood pregnancy test can tell ... goes up by 1 degree when you ovulate. Check the mucus in your vagina. It may become ...

  2. Female Reproductive System

    Science.gov (United States)

    ... pass certain characteristics of themselves to the next generation through their genes , the special carriers of human ... is pronounced: yoo-REE-thruh) and vagina. Once girls become sexually mature, the outer labia and the ...

  3. College Health: Sexual Health, Relationships, and Resources

    Science.gov (United States)

    ... issues that decisions are made about are the gender of partners, the type of contraception to use, ... if I was raped or sexually assaulted? The definition of rape is any penetration into your vagina ...

  4. Expanding Patient Options: Minilaparotomy for Hysterectomy

    Medline Plus

    Full Text Available ... specimen below the uterine artery. Again, for better visualization, I have removed the cervix on all but ... the Impact LigaSure, but, again, you have full visualization of the vagina. There have been a few ...

  5. Cervical Cap

    Science.gov (United States)

    ... vagina). It is considered one of the barrier methods of birth control because it provides a physical barrier between a ... getting pregnant depends on whether you use this method of birth control correctly and every time you have sex. In ...

  6. What I Need to Know about Bladder Control for Women

    Science.gov (United States)

    ... see your doctor regularly to check for small scrapes in the vagina that can result from using ... for urge incontinence. Many surgical options have high rates of success. Most stress incontinence problems are caused ...

  7. Robot-Assisted Gynecologic Surgery

    Medline Plus

    Full Text Available ... showed, and we see these large, sort of white-colored structures, their irregular surface and they correspond ... that uterus. That’s going t o leave another hole into the pelvis via the vagina, right? And ...

  8. Fístula vesicovaginal continente / Continent vesicovaginal fistula

    Scientific Electronic Library Online (English)

    Luís Gustavo Morato de, Toledo; Victor Espinheira, Santos; Paulo Eduardo Gourlat, Maron; Bruno César, Vedovato; Moacyr, Fucs; Marjo Deninson Cardenuto, Perez.

    2013-03-01

    Full Text Available A fístula vesicovaginal é uma comunicação anormal entre a bexiga e a vagina, sendo o tipo mais comum de fístula do trato urinário. A causa mais frequente no Brasil é a iatrogênica, secundária à histerectomia. Classicamente, as mulheres nessa condição, apresentam perda urinária contínua pela vagina e [...] ausência de micção, com forte impacto negativo na qualidade de vida. Apresentamos um caso de fístula vesicovaginal totalmente continente, com seguimento de 11 anos, sem complicações. Abstract in english Vesicovaginal fistula is an abnormal communication between the bladder and vagina and represents the most frequent type of fistula in the urinary tract. The most common cause in Brazil is iatrogenic fistula, secondary to histerectomia. Classically these women present continuous urinary leakage from [...] the vagina and absence of micturition, with strong negative impact on their quality of life. We present a case of totally continent vesicovaginal fistula, with a follow-up of 11 years with no complications.

  9. Dyspareunia: Painful Sex for Women

    Science.gov (United States)

    ... part of the genitals can cause pain during sex. Some conditions affect the skin around the vagina. ... types of birth control) does not fit correctly, sex may also be painful. Vaginismus (say: "vag-in- ...

  10. Robot-Assisted Gynecologic Surgery

    Medline Plus

    Full Text Available ... balloon we see below there? That’s a foley catheter balloon placed in the vagina. If we don’ ... around. The next morning after the surgery, the catheter comes out, the foley catheter comes out. They’ ...

  11. Sexual Problems

    Medline Plus

    Full Text Available ... occur with entry into the vagina or as deep pain. Both psychological and physical factors can contribute ... such as sexual abuse can be involved as well. Pain caused by lack of lubrication or by ...

  12. Sexual Problems

    Medline Plus

    Full Text Available ... or vaginal congestion, that is, no pleasurable sexual sensations in her clitoris or vagina. Male erectile disorder, ... be used by men and women to increase sensation to the genitals. Vaginal dilators are used to ...

  13. Ultrasound -- Pelvis

    Medline Plus

    Full Text Available ... an object, it bounces back, or echoes. By measuring these echo waves, it is possible to determine ... then inserted into the vagina. Only two to three inches of the transducer end are inserted into ...

  14. Vulvovaginitis in prepubertal girls

    OpenAIRE

    Stricker, T; Navratil, F; Sennhauser, F.

    2003-01-01

    This retrospective study evaluated the clinical features and findings in bacterial cultures and in microscopic examination of vaginal secretions in 80 prepubertal girls, aged 2–12 years, with vulvovaginitis. Vaginal secretions were obtained directly from the vagina with a sterile catheter carefully inserted into the vagina. Pathogenic bacteria were isolated in 36% of cases. In 59% of these cases the isolated pathogen was group A ß-haemolytic streptococcus. Candida was not found in any of t...

  15. In Vitro Activity of Nifuratel on Vaginal Bacteria: Could It Be a Good Candidate for the Treatment of Bacterial Vaginosis??

    OpenAIRE

    Togni, Giuseppe; Battini, Valeria; Bulgheroni, Anna; Mailland, Federico; Caserini, Maurizio; Mendling, Werner

    2011-01-01

    Bacterial vaginosis is characterized by a shift of the physiological flora to a diverse spectrum of bacteria, where Gardnerella vaginalis and Atopobium vaginae are the most important markers. In this study, the antimicrobial activity of nifuratel against G. vaginalis, A. vaginae, and lactobacilli was compared with that of the two currently used antibiotics metronidazole and clindamycin. Results suggest that nifuratel has a better spectrum of activity, being highly active against G. vaginalis ...

  16. Vesicovaginal reflux: A case report

    OpenAIRE

    Warade, Monali; Majid, Yameen; Dayananda, L.; Gupta, Kanchan

    2009-01-01

    Vesicovaginal reflux is a common cause of urinary incontinence in girls. A micturating cystourethrogram, which is the diagnostic investigation of choice, can demonstrate retrograde filling of the vagina during micturition and the complete emptying of the vagina at the end of micturition. Vesicovaginal reflux is a rare cause of gross hydrocolpos occurring without any anatomical obstruction. The condition may be associated with functional voiding disturbances.

  17. Magnetic resonance imaging of vaginal and vulval pathology

    Energy Technology Data Exchange (ETDEWEB)

    Griffin, N.; Grant, L.A.; Sala, E. [Addenbrooke' s Hospital, Department of Radiology, Box 219, Cambridge (United Kingdom)

    2008-06-15

    There are a number of conditions affecting the vagina and vulva that can be optimally assessed with the use of high-resolution magnetic resonance imaging (MRI). This paper gives a suggested protocol for MRI technique and sequences for imaging the pelvis and perineum and reviews the MRI appearances of many of the common pathologies affecting the vagina and vulva. Congenital anomalies, inflammatory and neoplastic entities such as vaginal and vulval carcinoma are discussed, with rarer malignancies also reviewed. (orig.)

  18. Anatomy of adult female common marmoset (Callithrix jacchus) reproductive system.

    OpenAIRE

    Cui, K. H.; Matthews, C. D.

    1994-01-01

    Better appreciation of the female reproductive anatomy of the common marmoset (Callithrix jacchus) should improve the prospects for nonsurgical embryo transfer in this model. Vaginal measurements were performed in 8 female adult marmoset monkeys. Four monkeys were measured at laparotomy for gross internal anatomy, and 1 monkey was analysed at autopsy. The vagina of the marmoset monkey was found to be divided into a lower and upper vagina with a marked vaginal isthmus between them. The mean le...

  19. Persistent Müllerian Duct Syndrome: a Case Report

    OpenAIRE

    Patil, Vijaya; Muktinaini, Sunilkrishna; Patil, Rashmi; Verma, Ashish

    2013-01-01

    Persistent Müllerian duct syndrome is a rare form of internal male pseudohermaphroditism caused by defects in synthesis or action of Müllerian-inhibiting factor, due to which Müllerian duct derivatives, such as uterus, fallopian tube, and upper vagina, are normally present in 46XY males. Here, we report a 26-year-old male with right-sided obstructed inguinal hernia with left undescended testis. On exploration, hernial sac containing bowel loops, uterus with fallopian tubes, upper vagina, a...

  20. Pregnancy following re-stenosis of complete transverse vaginal septum

    OpenAIRE

    Alka Sehgal; Shikha Rani; Navneet Takkar

    2013-01-01

    We report a case of 23 year woman who came to us with 6 weeks pregnancy and complete transverse vaginal septum. Cesarean section along with resection of septum was done. Restenosis of vagina was observed during puerperium. No surgical intervention was done. Spontaneous pregnancy with well- formed vagina was noted after 3 years. [Int J Reprod Contracept Obstet Gynecol 2013; 2(2.000): 229-230

  1. Demonstration of vaginal colonization with GusA-expressing Lactobacillus jensenii following oral delivery in rhesus macaques

    OpenAIRE

    Lagenaur, Laurel A.; Lee, Peter P.; Hamer, Dean H.; Sanders-beer, Brigitte E.

    2011-01-01

    The vaginal microbiome, which harbors beneficial Lactobacillus strains, is believed to be a major host defense mechanism for preventing infections of the urogenital tract. It has been suggested that the gastrointestinal tract serves as a reservoir for lactobacilli that colonize the vagina. Using rhesus macaques, we examined whether oral delivery of human vaginal Lactobacillus jensenii-1153-1646, a GusA-producing strain, would result in colonization of the rectum and the vagina. Lactobacilli w...

  2. Anatomia e histologia do conduto genital feminino de Pomacea canaliculata (Lamarck, 1822) (Mollusca, Gastropoda, Pilidae)

    OpenAIRE

    Eliana de Fátima Marques de Mesquita; Arnaldo Campos dos Santos Coelho; Jefferson Andrade dos Santos

    1990-01-01

    In this paper the authors give an anatomical and histological analysis of the genital duct in mature and immature females of Pomacea canaliculata (Lamarck, 1822). Anatomically, the vagina has an equal dimension in its extension, varying in form and volume, according to the maturation period. In the immaturity, it has a smaller diameter and volume. In the maturity, the vagina increases in volume, having the aspect of a tumescent organ, and in certain specimens shows an albuminous pink thread i...

  3. Histología uretral y vaginal en algunas hembras de mamíferos / Urethral and vaginal histology in some female mammals

    Scientific Electronic Library Online (English)

    J, Rodríguez-Antolín; E, Cuevas; L, Nicolás; V, Fajardo; F, Castelán; M, Martínez-Gómez.

    2012-04-01

    Full Text Available El análisis de las características histológicas de la uretra y la vagina en hembras de mamíferos es útil para entender la fisiología y la patología de procesos como la continencia urinaria, la cópula y el parto. En este contexto, las especies más estudiadas en cuanto a la organización tisular de la [...] uretra y vagina son la rata y la coneja. Es necesario estudiar con más detalle la organización tisular de la vagina y uretra en diferentes especies con fines de comparación. Tal información permitiría entender la diversidad funcional y conductual asociada a estos órganos. El presente documento reúne, compara y discute la información existente sobre las características histológicas de la uretra y la vagina en algunas hembras de mamíferos destacando aquellas de la coneja, modelo utilizado por nuestro grupo de investigación para estudiar la fisiología reproductiva y urinaria femenina. Abstract in english The analysis of the histological characteristics of the urethra and the vagina in female mammals is useful in understanding the physiology and pathology of processes such as urinary continence, copulation and delivery. In this regard, the species most studied with respect to the histological organis [...] ation of the urethra and vagina, are the rat and the rabbit. For comparative purposes, it is necessary to study in greater detail the histological organisation of the urethra and vagina in different species. The information gathered could help understand the functional and behavioural diversity associated with these organs. This study gathers, compares and discusses the existing information on the histological characteristics of the urethra and vagina in some mammal females, with emphasis on those of the rabbit, a model used by our research group to study female reproductive and urinary physiology.

  4. Vaginal position and length in the bitch: relationship to spaying and urinary incontinence

    International Nuclear Information System (INIS)

    A study was undertaken to determine if the vagina might be a suitable site for the measurement of intra-abdominal pressure during cystometry in the bitch, The position of the cranial vagina and vaginal length were measured radiographically and the effects of spaying and urinary Incontinence on these variables were evaluated in 30 continent and 30 incontinent bitches. The study used retrograde vaginourethrograms which had been obtained from animals used in a previous study, The cranial vagina was intra-abdominal on 36 of the vaginourethrograms, being least commonly intra-abdominal in incontinent bitches (11/30), Vaginal position was related linearly to vaginal length and continence status (P<0.01), while its length was related to bodyweight(P<0.01). Allowing for bodyweight, neutered animals had significantly shorter vaginas than entire bitches (P<0.01). Measurement of intra-abdominal pressure with concomitant measurement of intravesical pressure is essential if accurate assessment of detrusor pressure is to be determined during cystometry, The vagina is unlikely to be a useful location from which to measure intra-abdominal pressure since any pressure-measuring catheter inserted into it may fall outside the abdominal pressure zone. This is particularly true of neutered and/or incontinent bitches, the groups in which urodynamic investigations of urinary incontinence are most frequently indicated

  5. Sobre uma nova espécie do gênero Acanthocolpus Lühe, 1906 / On a new specie under Acanthocolpus Lühe, 1906

    Scientific Electronic Library Online (English)

    Berenice M. M., Fernandes; Santiago V. de, Souza.

    Full Text Available Os autores, na presente nota, propõem Acanthocolpus brasiliensis sp. n. sendo este gênero pela primeira vez referido no Brasil. A espécie aqui descrita difere das demais do gênero pela ausência de espinhos na vagina e no ducto hermafrodita e pela presença de vitelinos em quase toda extensão da metad [...] e posterior do corpo. Abstract in english In this paper the authors propose a new specie under Acanthocolpus Lühe, 1906 also reafirms this genus for the first time in Brasil. Acanthocolpus brasiliensis sp. n. differs from the other species of the genus by presenting folicular vitellaria in almost the hole area of the posterior part of the b [...] ody, by the absence of spines in vagina and in ejaculatory duct. A. brasiliensis sp. n. is similar to A. orientalis Srivastava, 1939, which differs also by the size of the body, cirrus sac and vagina.

  6. Colovaginal anastomosis: an unusual complication of stapler use in restorative procedure after Hartmann operation

    Directory of Open Access Journals (Sweden)

    Liao Guoqing

    2005-11-01

    Full Text Available Abstract Background Rectovaginal fistula is uncommon after lower anterior resection for rectal cancer. The most leading cause of this complication is involvement of the posterior wall of the vagina into the staple line when firing the circular stapler. Case presentation A 50-year-old women underwent resection for obstructed carcinoma of the sigmoid colon with Hartmann procedure. Four months later she underwent restorative surgery with circular stapler. Following which she developed rectovaginal fistula. A transvaginal repair was performed but stool passing from vagina not per rectum. Laporotomy revealed colovaginal anastomosis, which was corrected accordingly. Patient had an uneventful recovery. Conclusion Inadvertent formation of colovaginal anastomosis associated with a rectovaginal fistula is a rare complication caused by the operator's error. The present case again highlights the importance of ensuring that the posterior wall of vagina is away from the staple line.

  7. Anatomia e histologia do conduto genital feminino de Pomacea canaliculata (Lamarck, 1822) (Mollusca, Gastropoda, Pilidae)

    Scientific Electronic Library Online (English)

    Eliana de Fátima Marques de, Mesquita; Arnaldo Campos dos Santos, Coelho; Jefferson Andrade dos, Santos.

    Full Text Available [...] Abstract in english In this paper the authors give an anatomical and histological analysis of the genital duct in mature and immature females of Pomacea canaliculata (Lamarck, 1822). Anatomically, the vagina has an equal dimension in its extension, varying in form and volume, according to the maturation period. In the [...] immaturity, it has a smaller diameter and volume. In the maturity, the vagina increases in volume, having the aspect of a tumescent organ, and in certain specimens shows an albuminous pink thread in its lumen. Histologically, the calcigenic activity of the gland is evidentiated by the presence of an amorphous and basophilic mass, without nuclear material. This material has a fragmented aspect in the vagina lumen that reacts positively in van Kossa's coloured preparations for calcareous salts.

  8. Anatomia e histologia do conduto genital feminino de Pomacea canaliculata (Lamarck, 1822 (Mollusca, Gastropoda, Pilidae

    Directory of Open Access Journals (Sweden)

    Eliana de Fátima Marques de Mesquita

    1990-01-01

    Full Text Available In this paper the authors give an anatomical and histological analysis of the genital duct in mature and immature females of Pomacea canaliculata (Lamarck, 1822. Anatomically, the vagina has an equal dimension in its extension, varying in form and volume, according to the maturation period. In the immaturity, it has a smaller diameter and volume. In the maturity, the vagina increases in volume, having the aspect of a tumescent organ, and in certain specimens shows an albuminous pink thread in its lumen. Histologically, the calcigenic activity of the gland is evidentiated by the presence of an amorphous and basophilic mass, without nuclear material. This material has a fragmented aspect in the vagina lumen that reacts positively in van Kossa's coloured preparations for calcareous salts.

  9. Posterior vaginal wall cyst of Mullerian origin: a case report

    Directory of Open Access Journals (Sweden)

    Sunita Samal

    2015-02-01

    Full Text Available Cystic lesions of vagina are relatively uncommon and an incidental finding during routine gynaecological examination. Mullerian cysts are congenital cysts of vagina, usually reported during childbearing age group. These cysts mostly arise at the level of cervix and extend anteriorly in relation to bladder, but very rarely they may also extend posteriorly. This is a rare case of posterior vaginal wall cyst of Mullerian origin. A 36-year-old multi para (P2L2 both SVD, presented with a mass descending through vagina since 2-3 months. Pelvic examination revealed a 5x5 cm cystic mass arising from the posterior vaginal wall. Complete excision of the cyst was done. The cyst was filled with chocolate coloured material and histopathology confirmed a Mullerian cyst. [Int J Reprod Contracept Obstet Gynecol 2015; 4(1.000: 245-246

  10. Repair of a recurrent rectovaginal fistula with a biological graft.

    Science.gov (United States)

    Berger, Kate; Faro, Jonathan; Faro, Sebastian

    2015-07-01

    This case involves a patient with the congenital absence of the lower third of the vagina. While undergoing surgical restoration of the vagina, she sustained a laceration, which ultimately led to the development of a rectovaginal fistula. After two unsuccessful attempts at repair, the recommendation was for a diverting colostomy with another attempted repair, and she presented to our clinic to discuss other possible surgical options. The patient underwent repair of the fistula using a porcine-derived small intestinal submucosal extracellular matrix graft, which resulted in the repair of the rectovaginal fistula without recurrence at 18 months' follow-up. PMID:25941124

  11. Síndrome de Morris / Morris Syndrome

    Scientific Electronic Library Online (English)

    Julio Aurelio, Borrego López; Joel Alejandro, Varona Sánchez; Georgina, Areces Delgado; Luis Ernesto, Formoso Martín.

    2012-09-01

    Full Text Available Introducción: el síndrome de resistencia completa a los andrógenos, feminización testicular o síndrome de Morris, puede presentarse en uno de cada 20 000 a 64 000 recién nacidos varones. Objetivo: presentar un caso con genotipo masculino y fenotipo femenino dado por desarrollo mamario, con genitales [...] externos femeninos con hipoplasia de los labios mayores y menores y la vagina muy corta que termina en un fondo de saco ciego. Métodos: se valora en la consulta a una paciente adolescente de 19 años de edad con amenorrea primaria y contacto sexual insatisfactorio (imposibilidad de penetración). Resultados: se comprueba al examen vagina rudimentaria de unos dos centímetros y escaso desarrollo de genitales externos. En los exámenes complementarios se comprueban cifras de testosterona y LH aumentadas, así como el estradiol disminuido y un cariotipo 46 XY por lo que se sospecha síndrome de Morris y se planifica intervención quirúrgica combinada en un tiempo (vaginal y abdominal) donde se realiza anexectomía total derecha por video laparoscopia y reconstrucción de vagina por técnica de Williams. Posoperatorio satisfactorio y seguimiento ulterior por consulta donde se comprueba vagina funcional y estabilidad emocional de la paciente. Conclusiones: el estudio anatomo-patológico comprueba la existencia de ovario y testículo en la muestra quirúrgica lo que confirma el diagnóstico de síndrome de Morris o de resistencia completa a los andrógenos. Abstract in english Introduction:the syndrome of complete androgen resistance, testicular feminization or Morris syndrome may occur in one in 20 000 to 64 000 of male newborns. Objective: to present a case with male genotype and female phenotype given by breast development, female external genitalia with hypoplasia of [...] the labia and very short vagina ending in a blind pouch Methods: a 19 year- old female patient is assisted in consultation due primary amenorrhea and unsatisfactory sexual contact (impossibility of penetration). Results: at examination, we found a rudimentary vagina of about two inches and underdeveloped external genitalia. The exams confirmed increased LH and testosterone levels and decreased estradiol. It is also found a 46 XY karyotype, so Morris syndrome is suspected. Combined surgery is planned for the vagina and abdomen. Total videolaparoscopy right adnexectomy and vaginal reconstruction by technique of Williams are performed. We had satisfactory postoperative and subsequent follow-up consultation where functional vagina and emotional stability of the patient were checked. Conclusions: the pathological study verifies the existence of ovary and testis in the surgical specimen confirming the diagnosis of Morris syndrome or complete androgen resistance.

  12. A new species of Sciadiocara Skrjabin, 1916 (Nematoda: Acuariidae) parasitic in shorebirds in Argentina.

    Science.gov (United States)

    Cremonte, F; Navone, G T; Etchegoin, J A

    1999-03-01

    In the present paper we describe a new species of the genus Sciadiocara from Haematopus palliatus from the Mar Chiquita coastal lagoon (37 degrees 46' S, 57 degrees 27' W), Argentina. We provide two host records (H. palliatus and Larus dominicanus) for the genus, both from Buenos Aires province, Argentina. S. haematopodi n. sp. closely resembles S. legendrei Petter, 1967. The new species can be distinguished by the morphology of the distal end of the left spicule, the shorter length of the right spicule, the number of pre-anal papillae and the ratio of the length of the vagina vera to the length of the vagina uterina. PMID:10613539

  13. Acesso sagital transretal anterior (ASTRA) para vaginoplastia após complicação de anoretoplastia sagital posterior / Anterior sagittal transrectal approach (ASTRA) for vaginoplasty after complications of posterior sagittal anorectoplasty

    Scientific Electronic Library Online (English)

    Lisieux Eyer de, Jesus; Laura, Helman; Samuel, Dekermacher; Raquel L., Bernardo; Cruz Delia M., Martinez.

    2013-06-01

    Full Text Available A exposição transperineal de altas vaginas é limitada. Essas limitações podem ser contornadas usando ASTRA (anterior sagital transrectal approach). Relatamos o uso desta estratégia cirúrgica para o tratamento de um caso de atresia vaginal adquirida, após anorretoplastia posterior, em caso de malform [...] ação anorretal. Abstract in english Transperineal exposure of the high portion of the vagina is limited. These limitations can be circumvented using ASTRA (anterior sagittal transrectal approach). We report the use of this surgical strategy for the treatment of a case of acquired vaginal atresia after posterior anorectoplasty due to a [...] norectal malformation.

  14. [Laparoscopic modification of Vecchietti operation in the treatment of congenital vaginal aplasia].

    Science.gov (United States)

    Rechberger, T; Kotarski, J; Tarkowski, R; Jakowicki, J A

    1999-05-01

    Four young women aged 16-18 years were treated by laparoscopic modification of Vecchietti operation because of congenital vaginal aplasia. In all cases the postoperative period was uneventful and in every case functional vagina with the length 12 cm was achieved within 4 to 14 days of treatment. No pain killers were used during the olive traction in order to create a vagina. Our own instrumentarium necessary to perform such kind of operation was presented. Technical aspects of laparoscopic modification of Vecchietti operation were discussed. PMID:10462964

  15. Clear Cell Carcinoma Presented as a Large Polypoid Mass Expanding the Vaginal Fornix: Report of Two Cases

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Ji Young; Cho, Jae Ho [Dept. of Radiology, College of Medicine, Yeungnam University, Daegu (Korea, Republic of)

    2012-11-15

    Primary clear cell carcinoma of the vagina or uterine cervix is a very rare tumor. We report radiologic findings of two cases of clear cell carcinoma, arising in the vagina and uterine cervix in a 16-year-old and a 26-year-old female. These were presented as a large polypoid mass with a stalk and expanding the vaginal fornix. One case with ultrasonography showed relatively homogeneous echoic solid mass; the other case with a CT showed heterogeneously and strongly enhancing mass. All of the two cases showed non-specific signal intensity with heterogeneous and strong enhancement on MRI.

  16. AcEST: DK960412 [AcEST

    Lifescience Database Archive (English)

    Full Text Available TST39A01NGRL0007_F14 675 Adiantum capillus-veneris mRNA. clone: TST39A01NGRL0007_F14. 5' end seq ... 36|A2F336_TRIVA Chitinase, putative OS=Trichomonas vagina ... 36 1.9 tr|Q8GFD2|Q8GFD2_PHOLU Orf3 OS=Photorhab ... 36|A2F336_TRIVA Chitinase, putative OS=Trichomonas vagina lis G3 GN=TVAG_189160 PE=4 SV=1 Length = 739 Score ...

  17. AcEST: DK950002 [AcEST

    Lifescience Database Archive (English)

    Full Text Available TST38A01NGRL0007_H23 735 Adiantum capillus-veneris mRNA. clone: TST38A01NGRL0007_H23. 5' end seq ... 36|A2F336_TRIVA Chitinase, putative OS=Trichomonas vagina ... 36 2.3 tr|Q8GFD2|Q8GFD2_PHOLU Orf3 OS=Photorhab ... 36|A2F336_TRIVA Chitinase, putative OS=Trichomonas vagina lis G3 GN=TVAG_189160 PE=4 SV=1 Length = 739 Score ...

  18. AcEST: BP918170 [AcEST

    Lifescience Database Archive (English)

    Full Text Available YMU001_000110_D03 504 Adiantum capillus-veneris mRNA. clone: YMU001_000110_D03. BP918170 CL1960C ... F9|A2FIF9_TRIVA Flocculin, putative OS=Trichomonas vagina ... 33 5.8 tr|B4DHK0|B4DHK0_HUMAN cDNA FLJ60538, hi ... TRIVA Serine-rich protein, putative OS=Trichomonas vagina lis G3 GN=TVAG_244780 PE=4 SV=1 Length = 514 Score ...

  19. A rare case of posterior vaginal wall cyst

    OpenAIRE

    Jayaprakash, Sheela; M, Lakshmidevi; G, Sampath Kumar

    2011-01-01

    A 42-year-old multi para, presented with a mass protruding from vagina since 1 year. The mass was cystic in nature arising from the posterior vaginal wall. It was insidious in growth, gradually increasing in size to 8×8 cm. Surgical excision of the cyst was done by sharp and blunt dissection. The cyst was filled with mucoid material and histopathology confirmed a mullerian cyst. Cystic lesions of vagina are relatively uncommon and they are an incidental finding during gynaecological examinat...

  20. Scientific Rationale and Algorithmization of Sochi Resort Natural and Preformed Physical Therapeutic Factors in the Course of Combined Treatment of Patients with Chronic Vulvovaginitis

    Directory of Open Access Journals (Sweden)

    Kirill V. Gordon

    2012-11-01

    Full Text Available Chronic vulvovaginitis is the most wide-spread gynecological pathology among women of childbearing age. The chief causations of nonspecific vulvovaginitis are reduction in oestrogen, disturbances in vaginal acidity, intestine dysbacteriosis, local and general immune disturbances. The growth of vagina opportunistic pathogenic flora is closely connected with the increase of bacterial slimes on vagina mucus. Sulphur balneotherapy in the form of general baths and vaginal irrigations, mechanical physiotherapy promotes disruption of bacterial slimes, oestrogen elevation, immune reconstruction and vaginal biocenosis, which has positive effect on patients’ fertility level, frequency of obstetrical and perinatal pathologies.

  1. Interstitial therapy

    International Nuclear Information System (INIS)

    The use of various implant techniques is reviewed for primary radical treatment, implant boost of external beam treatment, perioperative implantation and salvage therapy. Radionuclides discussed are Radium 226, Cesium 137, Gold 198, Iodine 125, Iridium 192, Californium 252. Sites discussed are the tongue, lips, floor of the mouth, cheek, skin, anal canal and rectum, penis, breast, vagina, urethra, bladder and prostate. (U.K.)

  2. Covered exstrophy with anorectal malformation and vaginal duplication

    Directory of Open Access Journals (Sweden)

    Bawa Monika

    2011-01-01

    Full Text Available Covered exstrophy is a rare variant of the exstrophy-epispadias complex. We report a female newborn with covered exstrophy, absent anal opening and duplication of the introitus and the lower vagina. This rare, previously unreported, combination of anomalies highlights the complexity of the embryological events in the caudal area during separation of the hindgut and allantois.

  3. All about Menstruation (For Children)

    Science.gov (United States)

    ... the menstrual (say: MEN-strul) cycle, they usually mean the days when blood and tissue (menstrual fluid) leaves the body through the vagina. That's the most visible part of the process, and the part that girls and women need to manage. But the monthly ...

  4. Treatment Option Overview (Rectal Cancer)

    Science.gov (United States)

    ... exenteration : If the cancer has spread to other organs near the rectum, the lower colon , rectum, and bladder are removed. In women, the cervix , vagina , ovaries , and nearby lymph nodes may be removed. In men, the prostate may be removed. Artificial openings ( stoma ) are made for urine and stool ...

  5. 40 CFR 798.5450 - Rodent dominant lethal assay.

    Science.gov (United States)

    2010-07-01

    ...of administration are oral or by IP injection. Other routes may be appropriate...at least the duration of one estrus cycle or alternatively until mating has occurred as determined by the presence of sperm in the vagina or by the presence...

  6. Efficacy of Albaconazole against Candida albicans in a Vaginitis Model?

    OpenAIRE

    González, Gloria M.; Robledo, Efrén; Garza-González, Elvira; Elizondo, Mariana; González, J. Gerardo

    2009-01-01

    The efficacy of albaconazole (ABC) was evaluated using a murine model of vaginal Candida albicans infection. Both ABC and fluconazole (FLC) were effective in reducing the fungal load from vaginas of infected mice; however, ABC demonstrated encouraging activities against an FLC-resistant strain, with trends toward superiority over FLC in some treatment groups.

  7. Oxytocin determination by radioimmunoassay in cattle. 2

    International Nuclear Information System (INIS)

    Oxytocin concentration in jugular vein blood was measured radioimmunologically with a detection limit of 3 pg/ml plasma in male and female cattle. Five bulls were tested; during mating a cow in oestrus with intromission and ejaculation, during mounting a dummy or another bull with ejaculation into an artificial vagina or during false mounts. No increase in oxytocin concentrations could be observed, but stimulation with an electro-ejaculator caused an increase ranging from 5-84 pg/ml after a latent period of 3-5 min. A similar response was observed in two cows following the same procedure. The contact with a bull, false mount or mating with intromission and ejaculation was not followed by a measurable oxytocin release in 5 test cows. The following stimulation techniques, massage of vulva and clitoris, massage of cervix and uterus per rectum, artificial insemination, introduction of a speculum into the vagina or insufflation of air into the vagina were performed with 5 cows and 5 heifers. Insufflation of air into the vagina was the most effective stimulus, eleciting an oxytocin release up to 588 pg/ml. All 5 heiers responded positively, as well as 4 cows in oestrus. The other manipulations cuased an oxytocin response mainly in heifers (whether in oestrus or dioestrus), whereas only one cow in oestrus responded with an oxytocin release. In general, oxytocin concentrations increase about 30-90 s after the start of the stimulus. (author)uthor)

  8. Surgical Tutorial of a Robotic-Assisted Anterior Pelvic Exenteration

    Medline Plus

    Full Text Available ... contents will drop towards the chest, thereby allowing us to see and to be able to move lower down ... within the vagina. We're then able to see that move in and out and orient ourselves to very precisely remote any visible tumor that ...

  9. Limnomermis subtropicalis n. sp. (Nematoda:Mermithidae a Parasite of Larvae of Simulium orbitale Lutz (Diptera:Simuliidae in Argentina

    Directory of Open Access Journals (Sweden)

    Villalobos L Cristina de

    1997-01-01

    Full Text Available Limnomermis subtropicalis n. sp. (Nematoda: Mermithidae a parasite of Simulium orbitale Lutz (Diptera: Simuliidae found in Argentina is described and illustrated. This species is characterized by having medium sized amphids, pocket-shaped, medium sized vagina, sculptured spicule, and by having 9 preanal, 7 postanal papillae in the ventral row, and 12 papillae in the lateral rows

  10. Limnomermis subtropicalis n. sp. (Nematoda:Mermithidae) a Parasite of Larvae of Simulium orbitale Lutz (Diptera:Simuliidae) in Argentina

    OpenAIRE

    Cristina Villalobos, L.; Camino, Nora B.

    1997-01-01

    Limnomermis subtropicalis n. sp. (Nematoda: Mermithidae) a parasite of Simulium orbitale Lutz (Diptera: Simuliidae) found in Argentina is described and illustrated. This species is characterized by having medium sized amphids, pocket-shaped, medium sized vagina, sculptured spicule, and by having 9 preanal, 7 postanal papillae in the ventral row, and 12 papillae in the lateral rows

  11. Female Reproductive System

    Science.gov (United States)

    ... to the fetus via the umbilical cord. The amniotic fluid and membrane cushion the fetus against bumps and jolts to the mother's body. Pregnancy lasts an average of 280 days — about 9 ... loosens, and with amniotic fluid, comes out through the vagina when the ...

  12. Premature rupture of membranes

    Science.gov (United States)

    ... in this fluid. This membrane is called the amniotic sac. Often, the membranes rupture (break) during labor. This is often called " ... cervix, or vagina Too much stretching of the amniotic sac (this may ... on the membranes) Smoking If you have had surgery or biopsies ...

  13. Your First Pelvic Exam: A Guide for Teens

    Science.gov (United States)

    ... started to develop Whether you have ever had sex or have been sexually abused If you have vaginal itchiness or an unusual discharge (drainage) or odor from your vagina Getting Ready: If you find it helpful, your mom, sister or friend can stay with you. There ...

  14. Childhood lichen sclerosus is a rare but important diagnosis

    DEFF Research Database (Denmark)

    Jensen, Lise Soldbro; Bygum, Anette

    2012-01-01

    Lichen sclerosus (LS) is a chronic skin disorder with a predilection for the anogenital area. The disease is mostly seen in prepubertal and postmenopausal females. The lesions present as sharply demarcated white plaques encircling the vagina and anus. The atrophic form can lead to scarring of the affected area.

  15. Antimicrobial factors in the cervical mucus plug

    DEFF Research Database (Denmark)

    Hein, Merete; Valore, Erika V

    2002-01-01

    The cervical mucus plug is positioned between the microbe-rich vagina and the normally sterile uterine cavity, which suggests a host defense function, but few relevant data are available. We analyzed the composition and antimicrobial activity of cervical mucus plugs.

  16. Accessory Reproductive Organs Dimension of Two Species of Giant African Land Snails Archachatina marginata and Achatina achatina at Three Liveweight Ranges

    Directory of Open Access Journals (Sweden)

    J. A. Abiona

    2012-02-01

    Full Text Available A comparative study of the reproductive tract of two species of Giant African Land Snails, Archachatina marginata and Achatina achatina was carried out. Three groups of snails weighing 80-100,101-150 and 151-250 g were used in a 2x3 factorial design, with 5 replicates, involving a total of 30 snails. Dimensions and weights of retractor penile muscle, vas deferens, penis, vagina, oviduct, spermotheca, common duct, albumen gland and little hermaphrodite duct were taken. Results showed that Archachatina marginata had longer, wider and heavier accessory sex organs compared to Achatina achatina except for vas deferens width, vagina length, vagina width, and vagina weight, which were otherwise. Dimensions and weights of the accessory organs increased consistently with liveweight, except for retractor penile muscle width, which had attained maximum size by a body weight of 101-150 g. It can be concluded that Archachatina marginata had better reproductive tract dimension compared to their counterpart (Achatina achatina. It is however recommended that liveweight group 151-250 g be considered as group of choice when considering anatomical display of reproductive parts for demonstrative purpose and testing of manipulating tools for reproductive strategies in both species.

  17. Urogenital tumors

    Energy Technology Data Exchange (ETDEWEB)

    Weller, R.E.

    1994-03-01

    An overview is provided for veterinary care of urogenital tumors in companion animals, especially the dog. Neoplasms discussed include tumors of the kidney, urinary bladder, prostate, testis, ovary, vagina, vulva and the canine transmissible venereal tumor. Topics addressed include description, diagnosis and treatment.

  18. Single stage management of a unique variant of congenital pouch colon with triplet fistula and normal anus.

    Science.gov (United States)

    Pandey, Vaibhav; Gangopadhyay, Ajay Narayan; Gupta, Dinesh Kumar; Sharma, Shiv Prasad

    2015-01-01

    Congenital pouch colon (CPC) in the female patient presents with highly variable and anomalous anatomy. We herein report the first case of CPC with uterus didelphys having normal anal opening, H-type vestibular fistula, two other fistulous communications between pouch colon and two vagina managed in a single stage with excellent postoperative outcome. PMID:26166988

  19. Syndrome in question

    Scientific Electronic Library Online (English)

    Yinhua, Wu; Jianjun, Qiao; Hong, Fang.

    2014-09-01

    Full Text Available Vulvovaginal-gingival syndrome is characterized by erosions and desquamation of the vulva, vagina, and gingiva. We reported a case of a 32-year-old woman presenting with an 8-year history of damage to the vulval and perianal anatomy and limitation of mouth opening. The patient's symptoms were reliev [...] ed after treatment with topical tacrolimus cream.

  20. Robotic-Assisted Laparoscopic Sacrocolpopexy for Vaginal Vault Prolapse

    Medline Plus

    Full Text Available ... that is, leaving the cervix there. That of course assumes that the Pap smear history is completely negative. And if it's not, I ... the presacral space. This patient had reported a history of a prior MMK and a ... had detached from the top of the vagina. This mesh was still attached ...

  1. Vaginal birth - series (image)

    Science.gov (United States)

    ... sometimes called "bloody show" because it's tinged with blood. Before labor begins or in the early stages of labor, your amniotic sac may rupture and you may feel fluid trickle or gush out of your vagina. If your "bag of waters" doesn't break on its own, ...

  2. Treatment Option Overview (Uterine Sarcoma)

    Science.gov (United States)

    ... therapy to the pelvis. Treatment with tamoxifen for breast cancer . If you are taking this drug , have a pelvic exam every year and report any vaginal bleeding (other than menstrual bleeding) as soon as possible. Signs of uterine sarcoma include abnormal bleeding. Abnormal bleeding from the vagina ...

  3. Condiloma Acuminado

    Directory of Open Access Journals (Sweden)

    Juan Carlos Céspedes Escobar

    2011-06-01

    Full Text Available El Condilomas Acuminado es una enfermedadcausada por el Virus Papiloma Humano.Se caracteriza por el crecimiento de verrugas blandas en los genitales o en la regiónanal, o sea que crece entre los muslos y la parte interna de las nalgas, en el pene o en la vagina.

  4. Dicty_cDB: VHD790 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available VH (Link to library) VHD790 (Link to dictyBase) - - - Contig-U16441-1 VHD790P (Link to Original ... 5_1( AK137635 |pid:none) Mus musculus adult female vagina ... c... 47 7e-04 AK155045_1( AK155045 |pid:none) Mus ...

  5. Dicty_cDB: SFB715 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SF (Link to library) SFB715 (Link to dictyBase) - - - Contig-U14954-1 SFB715F (Link to Original ... 3_1( AK036973 |pid:none) Mus musculus adult female vagina ... c... 52 6e-06 (Q8BHA9) RecName: Full=Acid phosphat ...

  6. Dicty_cDB: VSA414 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available VS (Link to library) VSA414 (Link to dictyBase) - - - Contig-U14957-1 VSA414Z (Link to Original ... 6 1 BB146392 |BB146392.1 Mus musculus adult female vagina ... cDNA, RIKEN full-length enriched library, clone:99 ...

  7. Dicty_cDB: AHA892 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available AH (Link to library) AHA892 (Link to dictyBase) - G20488 DDB0231870 Contig-U15706-1 AHA892P (Lin ... 7_1( AK079457 |pid:none) Mus musculus adult female vagina ... c... 34 4.3 BC037694_1( BC037694 |pid:none) Mus mu ...

  8. Dicty_cDB: VFA869 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available VF (Link to library) VFA869 (Link to dictyBase) - - - Contig-U14527-1 VFA869P (Link to Original ... 3_1( AK137723 |pid:none) Mus musculus adult female vagina ... c... 33 5.0 AK054263_1( AK054263 |pid:none) Mus mu ...

  9. Gene : CBRC-MMUS-05-0090 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-MMUS-05-0090 5 A Relaxin receptors RXFP2_MOUSE 0.0 99% gb|EDL05874.1| relaxin/insulin-like ... 100% gnl|UG|Mm#S26686375 Mus musculus adult female vagina ... cDNA, RIKEN full-length enriched library, clone:99 ...

  10. Gene : CBRC-MMUS-01-0030 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-MMUS-01-0030 1 A UNKNOWN S100R_MOUSE 6e-20 92% emb|CAC47957.1| putative G-protein coupled r ... 100% gnl|UG|Mm#S10844542 Mus musculus adult female vagina ... cDNA, RIKEN full-length enriched library, clone:99 ...

  11. Dicty_cDB: SFD510 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SF (Link to library) SFD510 (Link to dictyBase) - - - Contig-U14954-1 SFD510F (Link to Original ... 3_1( AK036973 |pid:none) Mus musculus adult female vagina ... c... 54 5e-06 (Q8BHA9) RecName: Full=Acid phosphat ...

  12. AcEST: BP919927 [AcEST

    Lifescience Database Archive (English)

    Full Text Available YMU001_000130_G06 360 Adiantum capillus-veneris mRNA. clone: YMU001_000130_G06. BP919927 CL1225C ... J0|A2E6J0_TRIVA Chitinase, putative OS=Trichomonas vagina ... 33 5.5 tr|B4JN38|B4JN38_DROGR GH24212 OS=Drosop ...

  13. Dicty_cDB: VFJ196 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available VF (Link to library) VFJ196 (Link to dictyBase) - - - Contig-U14954-1 - (Link to Original site) ... 3_1( AK036973 |pid:none) Mus musculus adult female vagina ... c... 54 5e-06 (Q54P71) RecName: Full=Probable acid ...

  14. Antenatal MR diagnosis of urinary hydrometrocolpos due to urogenital sinus

    Energy Technology Data Exchange (ETDEWEB)

    Subramanian, Subramanian; Sharma, Raju; Gamanagatti, Shivanand [All India Institute of Medical Sciences, Department of Radiodiagnosis, New Delhi (India); Agarwala, Sandeep [All India Institute of Medical Sciences, Department of Pediatric Surgery, New Delhi (India); Gupta, Prerna; Kumar, Sunesh [All India Institute of Medical Sciences, Department of Obstetrics and Gynaecology, New Delhi (India)

    2006-10-15

    Hydrometrocolpos is cystic dilatation of the vagina and uterus due to congenital vaginal obstruction. It may be secretory or urinary in character and manifests in the neonatal period with abdominal distension. Urinary hydrometrocolpos occurs in patients with urogenital sinus or cloacal anomaly. A rare case of antenatal MR diagnosis of urinary hydrometrocolpos due to urogenital sinus is presented. (orig.)

  15. Dicty_cDB: SSI546 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SS (Link to library) SSI546 (Link to dictyBase) - - - Contig-U11167-1 SSI546Z (Link to Original ... 1_1( AK037131 |pid:none) Mus musculus adult female vagina ... c... 142 5e-33 (A5PKG6) RecName: Full=Ubiquitin co ...

  16. Dicty_cDB: VHH759 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available VH (Link to library) VHH759 (Link to dictyBase) - - - Contig-U12433-1 | Contig-U13671-1 VHH759P ... 7_1( AK036837 |pid:none) Mus musculus adult female vagina ... c... 160 1e-37 BC160667_1( BC160667 |pid:none) Dan ...

  17. Dicty_cDB: SFI521 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SF (Link to library) SFI521 (Link to dictyBase) - - - Contig-U12884-1 SFI521P (Link to Original ... 8_1( AK036838 |pid:none) Mus musculus adult female vagina ... c... 137 6e-31 BC039762_1( BC039762 |pid:none) Mus ...

  18. Dicty_cDB: CHF734 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available CH (Link to library) CHF734 (Link to dictyBase) - - - Contig-U16440-1 CHF734P (Link to Original ... 5_1( AK137635 |pid:none) Mus musculus adult female vagina ... c... 43 0.010 AK155045_1( AK155045 |pid:none) Mus ...

  19. Dicty_cDB: VHP145 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available VH (Link to library) VHP145 (Link to dictyBase) - - - Contig-U16441-1 VHP145P (Link to Original ... 5_1( AK137635 |pid:none) Mus musculus adult female vagina ... c... 65 6e-09 AK155045_1( AK155045 |pid:none) Mus ...

  20. Dicty_cDB: VHN605 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available VH (Link to library) VHN605 (Link to dictyBase) - - - Contig-U16441-1 VHN605P (Link to Original ... 5_1( AK137635 |pid:none) Mus musculus adult female vagina ... c... 63 2e-08 AK155045_1( AK155045 |pid:none) Mus ...

  1. Dicty_cDB: SSF692 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SS (Link to library) SSF692 (Link to dictyBase) - - - Contig-U14957-1 SSF692E (Link to Original ... 7 2 BB146392 |BB146392.1 Mus musculus adult female vagina ... cDNA, RIKEN full-length enriched library, clone:99 ...

  2. Dicty_cDB: SSI631 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SS (Link to library) SSI631 (Link to dictyBase) - - - Contig-U16441-1 SSI631E (Link to Original ... 5_1( AK137635 |pid:none) Mus musculus adult female vagina ... c... 38 0.29 AK155045_1( AK155045 |pid:none) Mus m ...

  3. Dicty_cDB: SFA677 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SF (Link to library) SFA677 (Link to dictyBase) - - - Contig-U14954-1 SFA677P (Link to Original ... 3_1( AK036973 |pid:none) Mus musculus adult female vagina ... c... 59 2e-07 (Q8BHA9) RecName: Full=Acid phosphat ...

  4. Dicty_cDB: CHB793 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available CH (Link to library) CHB793 (Link to dictyBase) - - - Contig-U12884-1 CHB793P (Link to Original ... 8_1( AK036838 |pid:none) Mus musculus adult female vagina ... c... 66 4e-22 BC039762_1( BC039762 |pid:none) Mus ...

  5. Dicty_cDB: CFG293 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available CF (Link to library) CFG293 (Link to dictyBase) - - - Contig-U12884-1 CFG293P (Link to Original ... 8_1( AK036838 |pid:none) Mus musculus adult female vagina ... c... 139 3e-31 BC039762_1( BC039762 |pid:none) Mus ...

  6. AcEST: BP920831 [AcEST

    Lifescience Database Archive (English)

    Full Text Available YMU001_000142_C05 511 Adiantum capillus-veneris mRNA. clone: YMU001_000142_C05. BP920831 CL1923C ... 05|A2ES05_TRIVA Sec1 family protein OS=Trichomonas vagina ... 34 3.2 tr|A5K1X6|A5K1X6_PLAVI Syntaxin binding ...

  7. Gene : CBRC-MMUS-11-0043 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-MMUS-11-0043 11 A Neuromedin U receptors NMUR2_MOUSE 0.0 100% ref|NP_694719.2| neuromedin U ... 100% gnl|UG|Mm#S10844668 Mus musculus adult female vagina ... cDNA, RIKEN full-length enriched library, clone:99 ...

  8. Dicty_cDB: SSC834 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SS (Link to library) SSC834 (Link to dictyBase) - G02133 DDB0187553 Contig-U04625-1 SSC834E (Lin ... 2_1( AK036782 |pid:none) Mus musculus adult female vagina ... c... 73 2e-14 protein update 2009. 7. 6 PSORT psg: ...

  9. Dicty_cDB: CFB709 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available CF (Link to library) CFB709 (Link to dictyBase) - - - Contig-U14954-1 CFB709F (Link to Original ... 3_1( AK036973 |pid:none) Mus musculus adult female vagina ... c... 59 1e-07 (Q8BHA9) RecName: Full=Acid phosphat ...

  10. Dicty_cDB: VFA392 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available VF (Link to library) VFA392 (Link to dictyBase) - - - Contig-U14954-1 VFA392F (Link to Original ... 3_1( AK036973 |pid:none) Mus musculus adult female vagina ... c... 54 5e-06 (Q54P71) RecName: Full=Probable acid ...

  11. Dicty_cDB: SFH891 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SF (Link to library) SFH891 (Link to dictyBase) - - - Contig-U14971-1 SFH891F (Link to Original ... 3 2 BB141110 |BB141110.1 Mus musculus adult female vagina ... cDNA, RIKEN full-length enriched library, clone:99 ...

  12. Dicty_cDB: VFJ219 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available VF (Link to library) VFJ219 (Link to dictyBase) - - - Contig-U14954-1 - (Link to Original site) ... 3_1( AK036973 |pid:none) Mus musculus adult female vagina ... c... 59 1e-07 (Q8BHA9) RecName: Full=Acid phosphat ...

  13. Dicty_cDB: VFN436 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available VF (Link to library) VFN436 (Link to dictyBase) - - - Contig-U14954-1 - (Link to Original site) ... 3_1( AK036973 |pid:none) Mus musculus adult female vagina ... c... 59 8e-08 (Q8BHA9) RecName: Full=Acid phosphat ...

  14. Dicty_cDB: VFF366 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available VF (Link to library) VFF366 (Link to dictyBase) - - - Contig-U14954-1 VFF366P (Link to Original ... 3_1( AK036973 |pid:none) Mus musculus adult female vagina ... c... 59 2e-07 (Q8BHA9) RecName: Full=Acid phosphat ...

  15. Dicty_cDB: CHL734 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available CH (Link to library) CHL734 (Link to dictyBase) - - - Contig-U16441-1 - (Link to Original site) ... 5_1( AK137635 |pid:none) Mus musculus adult female vagina ... c... 59 4e-08 AK155045_1( AK155045 |pid:none) Mus ...

  16. Dicty_cDB: VFM877 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available VF (Link to library) VFM877 (Link to dictyBase) - - - Contig-U14954-1 - (Link to Original site) ... 3_1( AK036973 |pid:none) Mus musculus adult female vagina ... c... 54 5e-06 (Q54P71) RecName: Full=Probable acid ...

  17. Dicty_cDB: CHD877 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available CH (Link to library) CHD877 (Link to dictyBase) - - - Contig-U12884-1 - (Link to Original site) ... 8_1( AK036838 |pid:none) Mus musculus adult female vagina ... c... 78 3e-28 BC039762_1( BC039762 |pid:none) Mus ...

  18. Dicty_cDB: AFN153 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available AF (Link to library) AFN153 (Link to dictyBase) - - - - - (Link to Original site) AFN153F 600 - ... 3_1( AK036973 |pid:none) Mus musculus adult female vagina ... c... 59 1e-07 (Q8BHA9) RecName: Full=Acid phosphat ...

  19. Dicty_cDB: CHL526 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available CH (Link to library) CHL526 (Link to dictyBase) - - - Contig-U16440-1 CHL526P (Link to Original ... 5_1( AK137635 |pid:none) Mus musculus adult female vagina ... c... 63 2e-08 protein update 2009. 4. 8 PSORT psg: ...

  20. Dicty_cDB: VFD727 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available VF (Link to library) VFD727 (Link to dictyBase) - - - Contig-U14954-1 VFD727F (Link to Original ... 3_1( AK036973 |pid:none) Mus musculus adult female vagina ... c... 50 3e-05 (Q8BHA9) RecName: Full=Acid phosphat ...

  1. Dicty_cDB: SFC857 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SF (Link to library) SFC857 (Link to dictyBase) - - - Contig-U12884-1 SFC857P (Link to Original ... 8_1( AK036838 |pid:none) Mus musculus adult female vagina ... c... 139 2e-31 BC039762_1( BC039762 |pid:none) Mus ...

  2. Dicty_cDB: SFH361 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SF (Link to library) SFH361 (Link to dictyBase) - - - Contig-U14954-1 SFH361F (Link to Original ... 3_1( AK036973 |pid:none) Mus musculus adult female vagina ... c... 42 0.007 (Q8BHA9) RecName: Full=Acid phosphat ...

  3. Dicty_cDB: CHF321 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available CH (Link to library) CHF321 (Link to dictyBase) - - - Contig-U15338-1 | Contig-U16441-1 CHF321P ... 5_1( AK137635 |pid:none) Mus musculus adult female vagina ... c... 60 4e-08 protein update 2009. 3.31 PSORT psg: ...

  4. Dicty_cDB: SSM780 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SS (Link to library) SSM780 (Link to dictyBase) - - - Contig-U12246-1 SSM780E (Link to Original ... 2 2 BB148603 |BB148603.1 Mus musculus adult female vagina ... cDNA, RIKEN full-length enriched library, clone:99 ...

  5. Dicty_cDB: SLH660 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SL (Link to library) SLH660 (Link to dictyBase) - - - Contig-U11727-1 SLH660E (Link to Original ... 6_1( AK162686 |pid:none) Mus musculus adult female vagina ... c... 133 2e-30 AK129350_1( AK129350 |pid:none) Mus ...

  6. Fine-scale analysis of 16S rRNA sequences reveals a high level of taxonomic diversity among vaginal Atopobium spp.

    Science.gov (United States)

    Mendes-Soares, Helena; Krishnan, Vandhana; Settles, Matthew L; Ravel, Jacques; Brown, Celeste J; Forney, Larry J

    2015-06-01

    Although vaginal microbial communities of some healthy women have high proportions of Atopobium vaginae, the genus Atopobium is more commonly associated with bacterial vaginosis, a syndrome associated with an increased risk of adverse pregnancy outcomes and the transmission of sexually transmitted diseases. Genetic differences within Atopobium species may explain why single species can be associated with both health and disease. We used 16S rRNA gene sequences from previously published studies to explore the taxonomic diversity of the genus Atopobium in vaginal microbial communities of healthy women. Although A. vaginae was the species most commonly found, we also observed three other Atopobium species in the vaginal microbiota, one of which, A. parvulum, was not previously known to reside in the human vagina. Furthermore, we found several potential novel species of the genus Atopobium and multiple phylogenetic clades of A. vaginae. The diversity of Atopobium found in our study, which focused only on samples from healthy women, is greater than previously recognized, suggesting that analysis of samples from women with BV would yield even more diversity. Classification of microbes only to the genus level may thus obfuscate differences that might be important to better understand health or disease. PMID:25778779

  7. Gene : CBRC-MMUS-03-0051 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-MMUS-03-0051 3 A Relaxin receptors RXFP1_MOUSE 0.0 98% ref|NP_997617.1| relaxin/insulin-lik ... 98% gnl|UG|Mm#S26686375 Mus musculus adult female vagina ... cDNA, RIKEN full-length enriched library, clone:99 ...

  8. Dicty_cDB: VHL539 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available VH (Link to library) VHL539 (Link to dictyBase) - G23489 DDB0216684 Contig-U12525-1 VHL539P (Lin ... 7_1( AK137637 |pid:none) Mus musculus adult female vagina ... c... 64 5e-09 (Q6P9P8) RecName: Full=DENN domain-c ...

  9. Dicty_cDB: VHP228 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available VH (Link to library) VHP228 (Link to dictyBase) - - - Contig-U16441-1 VHP228P (Link to Original ... 5_1( AK137635 |pid:none) Mus musculus adult female vagina ... c... 69 4e-10 AK155045_1( AK155045 |pid:none) Mus ...

  10. Dicty_cDB: AFH823 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available AF (Link to library) AFH823 (Link to dictyBase) - - - Contig-U14954-1 AFH823F (Link to Original ... 3_1( AK036973 |pid:none) Mus musculus adult female vagina ... c... 52 8e-06 (Q8BHA9) RecName: Full=Acid phosphat ...

  11. Lesions of skene glands and periurethral region: a review.

    Science.gov (United States)

    Heller, Debra S

    2015-04-01

    The periurethral (Skene) glands may become involved by a variety of conditions. Mass-like lesions need to be distinguished from other lesions arising from the anterior vagina. Familiarity with these lesions will be helpful if a patient with a lesion of the Skene glands or periurethral region is encountered. PMID:24983349

  12. Dicty_cDB: SFB453 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SF (Link to library) SFB453 (Link to dictyBase) - - - Contig-U14954-1 SFB453F (Link to Original ... 3_1( AK036973 |pid:none) Mus musculus adult female vagina ... c... 52 7e-06 (Q8BHA9) RecName: Full=Acid phosphat ...

  13. Dicty_cDB: AFJ692 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available AF (Link to library) AFJ692 (Link to dictyBase) - - - Contig-U14954-1 AFJ692F (Link to Original ... 3_1( AK036973 |pid:none) Mus musculus adult female vagina ... c... 59 1e-07 (Q8BHA9) RecName: Full=Acid phosphat ...

  14. Dicty_cDB: VHI405 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available VH (Link to library) VHI405 (Link to dictyBase) - - - Contig-U12433-1 | Contig-U13671-1 VHI405P ... 7_1( AK036837 |pid:none) Mus musculus adult female vagina ... c... 150 9e-35 BC160667_1( BC160667 |pid:none) Dan ...

  15. Dicty_cDB: AFI683 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available AF (Link to library) AFI683 (Link to dictyBase) - - - Contig-U14954-1 AFI683F (Link to Original ... 3_1( AK036973 |pid:none) Mus musculus adult female vagina ... c... 52 7e-06 (Q8BHA9) RecName: Full=Acid phosphat ...

  16. Dicty_cDB: SFG207 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SF (Link to library) SFG207 (Link to dictyBase) - - - Contig-U14954-1 - (Link to Original site) ... 3_1( AK036973 |pid:none) Mus musculus adult female vagina ... c... 59 9e-08 (Q8BHA9) RecName: Full=Acid phosphat ...

  17. Gene : CBRC-MMUS-23-0004 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-MMUS-23-0004 UN A UNKNOWN S100R_MOUSE 3e-24 69% ref|XP_984257.2| PREDICTED: hypothetical pr ... 90% gnl|UG|Mm#S10844542 Mus musculus adult female vagina ... cDNA, RIKEN full-length enriched library, clone:99 ...

  18. Dicty_cDB: Contig-U14380-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available Contig-U14380-1 no gap 479 2 7954818 7955287 PLUS 1 1 U14380 0 0 0 0 0 0 0 0 0 1 0 0 0 0 Show Co ... .. 46 1.1 1 ( AK137668 ) Mus musculus adult female vagina ... cDNA, RIKEN full... 46 1.1 1 ( AK037162 ) Mus musc ...

  19. Dicty_cDB: VHI305 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available VH (Link to library) VHI305 (Link to dictyBase) - G23434 DDB0233670 Contig-U12433-1 | Contig-U13 ... 7_1( AK036837 |pid:none) Mus musculus adult female vagina ... c... 161 5e-38 BC160667_1( BC160667 |pid:none) Dan ...

  20. Dicty_cDB: VHD531 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available VH (Link to library) VHD531 (Link to dictyBase) - - - Contig-U14527-1 VHD531P (Link to Original ... 3_1( AK137723 |pid:none) Mus musculus adult female vagina ... c... 33 8.1 AK054263_1( AK054263 |pid:none) Mus mu ...

  1. Dicty_cDB: CHB374 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available CH (Link to library) CHB374 (Link to dictyBase) - - - Contig-U12884-1 CHB374P (Link to Original ... 8_1( AK036838 |pid:none) Mus musculus adult female vagina ... c... 139 2e-31 BC039762_1( BC039762 |pid:none) Mus ...

  2. Candidíase vulvovaginal: fatores predisponentes do hospedeiro e virulência das leveduras Vulvovaginal candidiasis: susceptibility factors of the host and virulence of the yeasts

    OpenAIRE

    Cassiana Aparecida Álvares; Terezinha Inez Estivalet Svidzinski; Márcia Edilaine Lopes Consolaro

    2007-01-01

    INTRODUÇÃO: Leveduras do gênero Candida são patógenos oportunistas freqüentemente isolados das superfícies mucosas de indivíduos normais, mas podem levar ao desenvolvimento de infecções denominadas candidíases, que variam desde lesões superficiais até infecções disseminadas. OBJETIVOS: Ampliar os conhecimentos sobre candidíase vulvovaginal (CVV: infecção de vulva e vagina, causada por leveduras comensais que habitam a mucosa vaginal) e candidíase vulvovaginal recorrente (CV...

  3. Multikulturní dialog v Monologu o vaginach.

    Czech Academy of Sciences Publication Activity Database

    Uhde, Zuzana

    2005-01-01

    Ro?. 6, ?. 1 (2005), s. 39-40. ISSN 1213-0028 R&D Projects: GA AV ?R(CZ) 1QS700280503 Institutional research plan: CEZ:AV0Z70280505 Keywords : Vagina Monologues * gender justice * multiculturalism Subject RIV: AO - Sociology, Demography www.genderonline.cz

  4. Robot-Assisted Gynecologic Oncology Surgery

    Medline Plus

    Full Text Available ... 04 CHRISTOPHER STANLEY, MD: I think specifically endometrial cancer, if the patient's a surgical candidate, which means if the disease is limited to the uterus and not extended to the pelvic sidewalls, to the bladder, to the lower vagina. If you can with ...

  5. Robotic-Assisted Laparoscopic Sacrocolpopexy for Vaginal Vault Prolapse

    Medline Plus

    Full Text Available ... is not where it fails. It's going to fail at the vagina. That can happen for a number of reasons. I think potentially it can happen if there are too few sutures placed at the apex, if the ...

  6. Scrotal perforation of peritoneal catheter: a rare complication of ventriculoperitoneal shunts

    OpenAIRE

    Saeidi Borojeni, Hamid Reza; Fakheri, Taravat; Saeidi Borojeni, Sepehr

    2012-01-01

    The standard treatment for the hydrocephalus is ventriculoperitoneal shunts (VPS) operation that diverts the excess accumulated cerebrospinal fluid (CSF) from the ventricles or other CSF containing spaces to another area. The VPS operation has been reportedly associated with risk factor for different organs due to peritoneal catheter migration including umbilicus, anus, vagina, mouth, intestine, internal jugular vein, chest, liver.

  7. Perfuração vaginal como complicação de derivação ventrículo-peritoneal apresentação de um caso Vaginal perforation following ventriculoperitoneal shunt: case report

    Directory of Open Access Journals (Sweden)

    Geraldo Pianetti Filho

    1991-09-01

    Full Text Available É descrito um caso de saída, pela vagina, do catéter de derivação ventrículo-peritoneal. A possível causa e as consequências são discutidas.Report of a case with vaginal perforation by the catheter following a ventri-culoperitoneal shunt. The possible causative factor and results observed are discussed.

  8. Virulence Factors of Escherichia coli Isolated From Female Reproductive Tract Infections and Neonatal Sepsis

    OpenAIRE

    Hull, Richard A.; Hammill, Hunter A.; Susan W. Cook

    2001-01-01

    Objective: The presence of enterobacteria such as Escherichia coli in the vagina of normal women is not synonymous with infection. However, vaginal E. coli may also cause symptomatic infections. We examined bacterial virulenceproperties that may promote symptomatic female reproductive tract infections (RTI) and neonatal sepsis.

  9. Efecto del método de obtención de semen de ovino sobre la calidad espermática (Effect of the method of obtaining of ovine semen on the spermatic quality

    Directory of Open Access Journals (Sweden)

    Córdova-Izquierdo, Alejandro1*; ; ; y

    2006-08-01

    Full Text Available La colecta del semen del ganado ovino, ayuda a identificar problemas relacionados con el desempeño reproductivo de estos animales. Se han utilizado diferentes pruebas laboratoriales, para valorar la calidad seminal de los ovinos y poder realizar predicciones indirectas del potencial reproductivo de los machos reproductores; no obstante, su naturaleza subjetiva, no asegura el poder de fecundación de los machos. El objetivo de este trabajo fue valorar el efecto del método de obtención del semen de ovinos sobre la calidad espermática. Se empelaron 10 machos ovinos de la raza Suffolk de una Unidad de Producción Ovina, ubicada en el Estado de México, México. Para la recolección seminal se utilizó vagina artificial y directamente de la vagina, después de la monta natural. El semen fue valorado macro y microscópicamente. Los resultados promedios fueron, para vagina artificial: volumen 1.11 ml, pH 6.62, motilidad 64.5 %, concentración de espermatozoides/ml 206.4 x106, vivos 68.5 %, Muertos 31.87% y anormalidades 23.96%; directamente de la vagina: volumen 0.57 ml, pH 6.75, motilidad 60.4%, concentración de espermatozoides/ml 176.02 x 106, vivos 62.62 %, muertos 37.27% y anormalidades 11.12%. Los resultados indican que los resultados obtenidos con vagina artificial fueron los mejores. The collection of the semen of the livestock ovine, helps to identify problems related with the reproductive acting of these animals. They have been used different you prove laboratories, to value the seminal quality of the ovines and power to carry out indirect predictions of the reproductive potential of the reproductive males; nevertheless, its subjective nature, doesn't assure the power of fecundation of the males. The objective of this work was to value the effect of the method of obtaining of the ovines semen on the spermatic quality. You empelaron 10 male ovines of the race Suffolk of a Unit of Production Ovine, located in the State of Mexico, Mexico. For the seminal gathering artificial vagina was used and directly of the vagina, after it mounts it natural. The semen was valued macro and microscopically. The results averages were, for artificial vagina: volume 1.11 ml, pH 6.62, motility 64.5%, concentration of sperms/ml 206.4 x106, alive 68.5%, Dead 31.87% and abnormalities 23.96%; directly of the vagina: volume 0.57 ml, pH 6.75, motility 60.4%, sperms/ml concentration 176.02 x 106, alive 62.62%, dead 37.27% and abnormalities 11.12%. The results indicate that the results obtained with artificial vagina were the best.

  10. Morfologia e histologia do oviduto de marrecas Ana boschas / Morphology and histology of Ana Boschasfemale ducks oviduct

    Scientific Electronic Library Online (English)

    C., Moraes; S.M., Baraldi-Artoni; M.R., Pacheco; M., Nishizawa; L.S.O., Nakaghi.

    2010-04-01

    Full Text Available Avaliaram-se o comprimento do infundíbulo, do magno, do istmo, do útero e da vagina e o número de pregas do magno e do istmo do oviduto de 20 marrecas Ana boschas na fase reprodutiva. O infundíbulo apresenta mucosa com pregas longitudinais e baixas, revestidas por epitélio pseudoestratificado cilínd [...] rico ciliado, com células caliciformes. O magno, compartimento mais longo do oviduto, 25,38cm±3,20, encontra-se constituído por uma camada mucosa com pregas altas e espessas revestidas por células cilíndricas ciliadas e abundantes células caliciformes. O istmo é formado por uma mucosa com pregas estreitas e curtas e numerosas glândulas tubulares que se estendem para o interior da lâmina própria. O útero, região curta do oviduto, 5,25cm±1,26, apresenta parede com pregas e cristas baixas e numerosas glândulas tubulares enoveladas, dirigidas para o interior da lâmina própria. A vagina, um estreito tubo muscular, está constituído por oito anéis circulares, em média, e uma camada muscular altamente desenvolvida e espessa. A morfologia do oviduto da marreca apresenta características morfológicas e histológicas distintas dos galiniformes, observando-se que a vagina e a porção cranial do infundíbulo apresentam pregas e células caliciformes, respectivamente, sendo estas últimas estruturas ausentes nos galiniformes. Abstract in english The length of infundibulum, magnum, isthmus, uterus, vagina, and the number of oviduct, magnum, and isthmus folds were evaluated in 20 Ana boschas female ducks in the reproductive phase. The infundibulum presented mucous membrane with longitudinal and short folds, covered by ciliated columnar pseudo [...] stratified epithelium, with goblet cells. Magnum, the longest oviduct compartment, 25.38cm±3.20, is constituted by mucous membrane with high and thick folds that are covered by ciliated columnar cells and many goblet cells. Isthmus is formed by mucous membrane with narrow and short folds, and many tubular glands that extend inside lamina propria. Uterus, an oviduct short region, 5.25cm±1.26, presented surface with short folds and crests, and numerous reeled tubular glands, that are directed inside lamina propria. Vagina, a strait muscular tube, is constituted by, approximately, eight circular rings, and a very developed and thick muscular layer. The oviduct morphology of female ducks presented different morphological and histological characteristics from Galliformes, because vagina and infundibulum cranial portion present folds and goblet cells, respectively, and the last cited structures are absent in Galliformes.

  11. Morfologia e histologia do oviduto de marrecas Ana boschas Morphology and histology of Ana Boschasfemale ducks oviduct

    Directory of Open Access Journals (Sweden)

    C. Moraes

    2010-04-01

    Full Text Available Avaliaram-se o comprimento do infundíbulo, do magno, do istmo, do útero e da vagina e o número de pregas do magno e do istmo do oviduto de 20 marrecas Ana boschas na fase reprodutiva. O infundíbulo apresenta mucosa com pregas longitudinais e baixas, revestidas por epitélio pseudoestratificado cilíndrico ciliado, com células caliciformes. O magno, compartimento mais longo do oviduto, 25,38cm±3,20, encontra-se constituído por uma camada mucosa com pregas altas e espessas revestidas por células cilíndricas ciliadas e abundantes células caliciformes. O istmo é formado por uma mucosa com pregas estreitas e curtas e numerosas glândulas tubulares que se estendem para o interior da lâmina própria. O útero, região curta do oviduto, 5,25cm±1,26, apresenta parede com pregas e cristas baixas e numerosas glândulas tubulares enoveladas, dirigidas para o interior da lâmina própria. A vagina, um estreito tubo muscular, está constituído por oito anéis circulares, em média, e uma camada muscular altamente desenvolvida e espessa. A morfologia do oviduto da marreca apresenta características morfológicas e histológicas distintas dos galiniformes, observando-se que a vagina e a porção cranial do infundíbulo apresentam pregas e células caliciformes, respectivamente, sendo estas últimas estruturas ausentes nos galiniformes.The length of infundibulum, magnum, isthmus, uterus, vagina, and the number of oviduct, magnum, and isthmus folds were evaluated in 20 Ana boschas female ducks in the reproductive phase. The infundibulum presented mucous membrane with longitudinal and short folds, covered by ciliated columnar pseudostratified epithelium, with goblet cells. Magnum, the longest oviduct compartment, 25.38cm±3.20, is constituted by mucous membrane with high and thick folds that are covered by ciliated columnar cells and many goblet cells. Isthmus is formed by mucous membrane with narrow and short folds, and many tubular glands that extend inside lamina propria. Uterus, an oviduct short region, 5.25cm±1.26, presented surface with short folds and crests, and numerous reeled tubular glands, that are directed inside lamina propria. Vagina, a strait muscular tube, is constituted by, approximately, eight circular rings, and a very developed and thick muscular layer. The oviduct morphology of female ducks presented different morphological and histological characteristics from Galliformes, because vagina and infundibulum cranial portion present folds and goblet cells, respectively, and the last cited structures are absent in Galliformes.

  12. The effect of semen collection method and level of egg yolk on capability of dilution and storage of buck semen

    Directory of Open Access Journals (Sweden)

    N.N. Dhaher

    2013-12-01

    Full Text Available The study was conducted to evaluate the effect of semen collection method for reduction of the deleterious interaction between the enzymes of bulbourethral gland and egg yolk during the dilution and storage of buck semen by three different level of egg yolk. Ten bucks were used in this study; the bucks were divided into two groups (five bucks in each group. Semen samples were collected once a week for four weeks from the bucks in first group using an artificial vagina, and from the animals in second group using an electroejaculator. The collected semen samples were diluted with sodium citrate extender with three different level of egg yolk (5, 10 and 20%. Extend semen samples were stored at 5 °C for three days. Computer assisted sperm analysis and Sperm Class Analyzer® were used for evaluation of the buck semen samples. Sperm motility parameters were evaluated which includes; percentage of motile sperm, percentage of progressive motile sperm, the value of the linear velocity (VSL, the value of the average velocity (VAP, the value of the curvilinear velocity (VCL, and the amplitude of lateral movement of the head (ALH. Results showed that all sperm motility parameters under the different level of egg yolk in semen samples that collected by artificial vagina were significantly higher than those which collected by electroejaculator. The percentage of motile sperm and progressive motile sperm of samples that collected by artificial vagina were higher at 10% of egg yolk, while these motility parameters were higher at 5% of egg yolk for semen samples that collected by electroejaculator. The differences between the two methods of semen collection in VCL and ALH were clear and the values were higher in samples that collected using the artificial vagina. The values of VSL, VAP and VCL of semen samples that collected by artificial vagina were higher at the second day than first day of semen storage under 10% of egg yolk. In conclusion, there are effects of the semen collection method on ability of dilution and storage of buck semen, and using of artificial vagina and 10% of egg yolk is recommended for buck semen dilution and storage.

  13. Amputação abdômino-perineal mais colostomia para-vaginal no tratamento do câncer reto-anal Abdomino-perineal amputation plus para-vaginal colostomy in the treatment of reto-anal cancer

    Directory of Open Access Journals (Sweden)

    Alcino Lázaro da Silva

    2009-12-01

    Full Text Available O apresenta uma proposta e as tentativas iniciais para evitar a colostomia abdominal quando esta tem que ser definitiva. Na mulher foi possível a sua execução, desde que se aproveitou o tono da musculatura esfincteral vulvovaginal quando ela pode ser preservada na amputação de reto-ânus. O colo, preparado com as válvulas, desce posteriormente à vagina, por dentro do conjunto esfincteral vulvovaginal. As observações iniciais mostram que esta tentativa poderia ser incrementada para melhores estudos de continência.The Author presents a proposal and lhe initial attempties to avoid the abdominal colostomy when it has to be definitive. In the woman was possible its execution, since it took advantage from the vulvovaginal esfincteral muscle nohen it can be preserved ot the anus-rectum amputation. The colon, prepared wit the valves, descend posteriorily from the vagina, inside the vulvo-vaginal esfincteral group. The initial observations shows that this attempt could be better developed for cotinency etudies.

  14. FORMULATION, EVALUATION AND MICROBIAL ASSAY OF TINIDAZOLE VAGINAL SUPPOSITORY CONTAINING LACTIC ACID BACILLUS SPORES

    Directory of Open Access Journals (Sweden)

    SC Shivhare*, AR Umarkar and PA Salunke

    2014-07-01

    Full Text Available Human vagina represents a dynamic ecosystem dominated by certain species of Lactobacillus. This microorganism restricts the growth of pathogens by using properties of steric exclusion and inhibitory substance production. Serious complications including bacterial vaginosis and vaginal cancer are often determined in women with reduced numbers of lactobacilli. Local application of Lactobacillus is consequently promising to keep the vagina colonized by this strain, which consequently reduces the infections. The first objective of this research was to develop a local application pharmaceutical formulation of a vaginal suppository containing lyophilized culture of Lactobacillus with anti-microbial agent tinidazole. The second objective was to establish its in vivo performance by developing in vitro methods of evaluation as well as antimicrobial activity of tinidazole alone with Lactic acid Bacillus Spores in vaginosis.

  15. Reconstructive surgical management of cryptomenorrhoea because of complete vaginal agenesis

    Directory of Open Access Journals (Sweden)

    Krishna Dahiya

    2011-12-01

    Full Text Available Background: The Vagina is a composite structure formed partly from the mullerian duct and partly from urogential sinus. Most of the patients with mullerian agenesis have small rudimentary uterus without any endometrial cavity, 7% - 8% may have functioning uterus. Case: A 15 years old girl admitted with primary amenorrhea, cyclical abdominal pain, hematometra and complete vaginal agenesis. Surgical correction is the mainstay of treatment in patients with functioning uterus and absent vagina. Vaginoplasty was done to reconstruct a neovagina using amnion graft and establish uterovaginal continuity. In this case we have used only perineal approach to dissect the neovagina and identify the cervix with formation of a patent drainage tract and adequate vaginal length of 9 cm. Conclusion: In rare cases of obstructed functioning uterus by complete vaginal agenesis, vaginoplasty effectively restores anatomy and function by an overall minimal operative morbidity. Human amnion provides excellent results in neovaginal reconstruction.

  16. Vaginal Smear TNF-alpha, IL18, TLR4, and GATA3 mRNA Levels Correlate with Local Inflammation

    Directory of Open Access Journals (Sweden)

    Olga Bourmenskaya

    2014-12-01

    Full Text Available Background: A molecular approach to estimation of local inflammatory response associated with dysbiotic conditions of the vagina is reported. This approach is based on immune response gene transcription levels measured by qPCR assay. Methods and Results: qPCR analysis of 24 immune response gene transcripts in vaginal smears was performed for 215 women with vaginitis and 95 healthy controls. The data were sorted by comparison to local inflammatory response profiles assessed by conventional methods. The local inflammatory response in the vagina is found to correlate with TNF-alpha, IL18, TLR4, and GATA3 transcript levels. Sensitivity and specificity of the approach, as validated in accordance with conventional clinical examination results, are 94.9% and 93.7%, respectively. Conclusions: The noninvasive diagnostic approach to vaginal pathology based solely on its molecular characterization may prove to be clinically relevant.

  17. Natural orifice transluminal endoscopic surgery: The transvaginal route moving forward from cholecystectomy

    Directory of Open Access Journals (Sweden)

    Eduardo M Targarona

    2010-06-01

    Full Text Available The advent of minimally invasive surgery and the advances in endoluminal flexible endoscopy have converged to generate a new concept in digestive surgery, whose acronym natural orifice transluminal endoscopic surgery (NOTES, has become a familiar term in the surgical community. NOTES has been performed through the mouth, the bladder, the rectum and the vagina. Of these four approaches, the vagina has gained most popularity for several reasons. It is not only readily accessible and easy to decontaminate but it also provides safe entry and simple closure. The transvaginal approach has been described in the experimental and the clinical setting as an option for cholecystectomy, nephrectomy, splenectomy, segmental gastrectomy, retroperitoneal exploration and bariatric surgery. However, larger series are needed to delineate the exact risks of this approach, and to transcend cultural barriers that impede its wider introduction. Prospective randomized trials will shed light on the definitive role of the vaginal approach in minimal invasive surgery of the future.

  18. La ubiquitinacion de los espermatozoides durante su paso por el tracto reproductor de la coneja (Ubiquitination of the sperm during their passage through reproductive tract of the female rabbit

    Directory of Open Access Journals (Sweden)

    Toledano-Olivares A

    2011-03-01

    Full Text Available ResumenEl objetivo de este estudio fue conocer si las proteínas de la membrana plasmática de espermatozoides de conejo, se ubiquitinan durante su tránsito por el tracto reproductor de la hembra. Se utilizaron conejos Nueva Zelanda (10 machos y 10 hembras sexualmente maduros con fertilidad probada, a los machos se les realizó un espermograma, a las hembras se les dio monta natural y 5 horas después se sacrificaron por dislocación cervical. Se diseco eltracto reproductor y se ligaron las tres regiones anatómicas: vagina, útero y oviducto, se lavaron con PBS y se contaron los espermatozoides de cada región. Posteriormente se analizó el porcentaje de espermatozoides positivos a ubiquitina por microscopía de fluorescencia con el anticuerpo anti-Ub (P4D1, Los resultados fueron: en vagina se encontró un total de 42 ± 15 x 106, en útero 12 ± 8 x 106 y en oviducto 0.70 ± 0.10 x 106 espermatozoides.

  19. Small Bowel Evisceration Following Vaginal Hysterectomy is a General Surgical Emergency–A Case Report and Review of the Literature

    Directory of Open Access Journals (Sweden)

    Deb Maitra

    2011-03-01

    Full Text Available Small bowel evisceration through the vagina is a rare condition, which tends to affect post-menopausal women who have undergone vaginal hysterectomy. It is a surgical emergency with a favourable outcome if diagnosed and treated in a timely fashion. Delay in diagnosis can precipitate infarction of small bowel loops with associated morbidity and mortality. Treatment involves laparotomy, reduction of the incarcerated loops (plus/minus small bowel resection and repair of the vaginal rupture. The purpose of this paper is to report a case of small bowel evisceration through the vagina, to review the literature pertaining to this topic and to raise awareness of this condition in the general surgical community.

  20. Surgical repair of rectovaginal fistula using gracilis muscular flap. A case report

    Energy Technology Data Exchange (ETDEWEB)

    Inoue, Yasuhiro; Ooi, Masataka; Takeuchi, Kenji; Honzumi, Makoto [Nabari City Hospital, Mie (Japan); Fukunishi, Shigeji

    1999-07-01

    A 78 year-old female suffered from vaginal discharge of flatus and stool for 20 years after the radiation therapy for cervical cancer. Digital and endoscopic examination of the rectum and the vagina disclosed a large, short rectovaginal fistula at the level of the cervix. Since laparotomy and low anterior resection of the rectum were impossible, a perineal approach was adopted. After perineal skin incision, the fistula was resected and the defects of the rectum and the vagina were closed. Gracilis muscular flap was anchored between the two closures. Though the closure of the rectal side was torn, her postoperative course was uneventful. Endoscopic examination 24 days after the operation confirmed healing of the dehiscence. The results verified the usefulness of the perineal approach using the gracilis muscular flap as an alternative method to low anterior resection for troublesome radiation induced rectovaginal fistula. (author)

  1. Physical examination of the female internal and external genitalia with and without pelvic organ prolapse: A review.

    Science.gov (United States)

    Pahwa, Avita K; Siegelman, Evan S; Arya, Lily A

    2015-04-01

    Pelvic organ prolapse, a herniation of pelvic organs through the vagina, is a common condition in older women. Pelvic organ prolapse distorts vaginal anatomy making pelvic examination difficult. A clinician must accurately identify anatomic landmarks both in women presenting with symptoms of prolapse and in women noted to have coincidental prolapse during routine gynecologic examination. We present a systematic approach to the female pelvic examination including anatomic landmarks of the external genitalia, vagina, and uterus in women with normal support as well as changes that occur with pelvic organ prolapse. Knowledge and awareness of normal anatomic landmarks will improve a clinician's ability to identify defects in pelvic support and allow for better diagnosis and treatment of pelvic organ prolapse. PMID:25256076

  2. AIDS-related Kaposi sarcoma: findings on thallium-201 scintigraphy

    International Nuclear Information System (INIS)

    No simple, noninvasive method is available for evaluating extracutaneous Kaposi sarcoma in AIDS patients or for following the tumor's response to treatment. We report our preliminary experience with thallium-201 scintigraphy in nine AIDS patients with proved Kaposi sarcoma. Eight of the nine had abnormal uptake of the radionuclide in skin, lymph nodes, oral cavity, vagina, and lungs. Only four of the nine had cutaneous Kaposi sarcoma at the time of scanning. All cutaneous and mucosal lesions were thallium avid. Two of the six patients with thallium-avid nodes underwent nodal biopsy. Both biopsies confirmed the diagnosis of Kaposi sarcoma. Cutaneous Kaposi sarcoma developed later in one of these patients, showing the efficacy of thallium scintigraphy for the early detection of extracutaneous lesions. These preliminary results show thallium avidity in Kaposi sarcoma involving the skin and various extracutaneous sites (lymph nodes, lung, mucosa, and vagina). Thallium scintigraphy is a potentially useful procedure for detecting extracutaneous Kaposi sarcoma in AIDS patients

  3. Analysis of complications for the treatment of uterine fibroids with bilateral uterine artery superselective embolization

    International Nuclear Information System (INIS)

    Objective: To discuss the complications of the bilateral uterine artery superselective embolization for uterine fibroids. Methods: Forty one cases (mean 42 years old) with uterine fibroids were approached by right femoral artery puncture; including thirty six cases of single hysteromyoma (33 cases with diameter 10 cm). and 5 cases of multi hysteromyoma. Bilateral uterine artery super selective 5F catheterization embolization were done along uterine descending artery (neck of uterus to vagina) with PVA particles. Results: Embolization succeeded with 100% and effective ratio was 90.3%. Sixteen of these cases showed post embolization syndrome, with something outflowed from vagina and 10 cases showed changes of emmenia but with no serious complications in all 41 cases. Conclusion: Using bilateral uterine artery superselective embolization for uterine fibroids with PVA grains can decrease the incidence of complications. (authors)

  4. Description of Afenestrata koreana n. sp. (Nematoda: Heteroderinae), a Parasite, of Bamboo in Korea

    OpenAIRE

    Vovlas, N.; Lamberti, F.; Choo, H. Y.

    1992-01-01

    Afenestrata koreana n. sp. collected from roots of bamboo (Phyllostachys pubescens) in Gyeongnam Province in the southern part of the Korean peninsula is described and illustrated. Its primary differentiating characteristics are a globose to subspherical body in adults with a prominent neck and terminal cone, thick cuticle, terminal vulva, and deep vagina. Fenestra, bullae, and underbridge are absent. The anus is on the immediate posterior side of the cone. Superficial small tubercules cover ...

  5. Influence of addition of different antibiotics in semen diluent on viable bacterial count and spermatozoal viability of Awassi ram semen

    OpenAIRE

    O.I. Azawi; M A Ismaeel

    2012-01-01

    The objectives of the present study were to determine the effects of six different antibiotics in controlling the growth of semen contaminating bacteria and if these antibiotics have any adverse effect on Awassi ram spermatozoa. Semen samples from six mature Awassi rams were used in this study. A total number of 120 ejaculates were collected from the rams using an artificial vagina once a week. Semen ejaculates were evaluated for volume, sperm concentration, mass motility, individual motility...

  6. Evaluation of Reuterin Production in Urogenital Probiotic Lactobacillus reuteri RC-14?

    OpenAIRE

    Cadieux, Peter; Wind, Anette; Sommer, Philip; SCHAEFER, LAURA; Crowley, Kate; Britton, Robert A.; Reid, Gregor

    2008-01-01

    Classified as a distinct species in 1980, Lactobacillus reuteri strains have been used in probiotic formulations for intestinal and urogenital applications. In the former, the primary mechanism of action of L. reuteri SD2112 (ATCC 55730) has been purported to be its ability to produce the antibiotic 3-hydroxypropionaldehyde (3-HPA), also known as reuterin. In the vagina, it has been postulated that probiotic Lactobacillus reuteri RC-14 does not require reuterin production but mediates a resto...

  7. Candida albicans Adhesion to and Invasion and Damage of Vaginal Epithelial Cells: Stage-Specific Inhibition by Clotrimazole and Bifonazole?

    OpenAIRE

    Wächtler, Betty; Wilson, Duncan; Hube, Bernhard

    2011-01-01

    Clotrimazole and bifonazole are highly effective antifungal agents against mucosal Candida albicans infections. Here we examined the effects of low levels of clotrimazole and bifonazole on the ability of C. albicans to adhere, invade, and damage vaginal epithelial cells. Although adhesion and invasion were not affected, damage was greatly reduced upon azole treatment. This clearly indicates that low levels of azoles influence specific activities of C. albicans during distinct stages of vagina...

  8. Characterization of biofilm-forming microorganisms isolated from vaginal exudate in Portugal

    OpenAIRE

    Alves, P; Castro, J.; Cereija, Tatiana; Henriques, Ana Filipa Frutuoso Mendes; Cerca, Nuno

    2012-01-01

    Bacterial vaginosis (BV) is one of the most common gynaecological conditions affecting women in the reproductive age, and can lead to increase risk gynaecological infections and pre-term labour. The aetiology of this pathology is still poorly understood, but recent reports referring to the presence of anaerobic biofilms both in the healthy and BV vagina (with different microbial compositions) have led to the theory that the microorganisms that form biofilms may be relevant for the aetiology o...

  9. Treatment of vaginal infections: effectiveness of the association of metronidazole and clotrimazole

    OpenAIRE

    Simone Ferrero

    2013-01-01

    The normal vagina of women of reproductive age is colonised by lactobacilli that produce lactic acid, hydrogen peroxide and bacteriocins; these substances contribute to lowering the vaginal pH. A low vaginal pH creates an environment hostile to the growth of other microrganisms. When the number of lactobacilli is decreased, the resulting increase in the pH may favour vaginal infections. The three most common vaginal infections are bacterial vaginosis, trichomoniasis, and vaginal candidosis. T...

  10. Treatment with tibolone partially protects 3-D microarchitecture of lumbar Vertebral Bone Tissues and Prevents Ovariectomy-induced Reduction in Mechanical Properties : Ding M, Dalstra M, Weinans H, Ederveen AG, I Hvid

    OpenAIRE

    Ding, Ming

    2009-01-01

    Treatment with Tibolone partially Protects 3-D Microarchitecture of Lumbar Vertebral Bone Tissues and Prevents Ovariectomy-induced Reduction in Mechanical Properties Tibolone (Org OD14) is a tissue selective steroid with estrogenic effects on the brain, bone and vagina, without stimulating the breast and endometrium. A previous study has shown that longterm treatment with tibolone prevents ovariectomy (OVX) induced bone loss in rats. The aim of this study was to investigate the effects of tib...

  11. DISORDER OF SEX DEVELOPMENT: DESCRIPTION OF 2 CASES OF MALE PSEUDOHERMAPHRODITISM

    Directory of Open Access Journals (Sweden)

    M. Messina

    2009-11-01

    Full Text Available Introduction. "Genetic errors" with malformations and hormonal alterations result in a broad spectrum of disorders of sexual identity difficult to classify for etiopathogenesis and anatomy. Male pseudohermaphroditism (PEM is the result of defects in masculinisation, persistence of mullerian ducts or genital malformations. In these patients, there is always a 46 XY karyotype, male gonads with the external genitalia and phenotype completely or partially female. The authors describe 2 cases of PEM. Patients and Methods. RS and HNA, 9 and 15 years old. Both had 46 XY karyotype and female phenotype with the presence of penile clitoris and small vagina. The urethral meatus was positioned at the base of the penile clitoris and upper vagina and testicles, were located at the proximal portion of the inguinal canal.Patients were subjected to MRI showing absence of uterus and ovaries. The endoscopy described a small vagina dead-end about 4-5 cm long. Complete resection of the vagina, bilateral orchiopexy, correction of perineal hypospadias with urethral tubulization, reconstruction of the scrotum, with the results of penoscrotal hypospadias were performed. Discussion. Sexual differentiation is the process between VII and XII weeks of gestational age leading to formation of male or female fetus from embryo potentially bisexual. Brain Code gender is bipolar: male or female. In the sexual disorders there is a discrepancy between anatomical sex and the brain code. Genital malformation with a direct mechanism (external genitalia and indirect (prenatal pathological imprinting on all the receptors of target organs may exacerbate the brain deterioration of the code resulting in disease patterns difficult to manage according psychological and surgical aspects. Conclusions. Pediatric Surgeon plays a key role in the treatment of genital anomalies. Valutation of pelvic-perineal anatomy is important for the choice of sexual phenotype and related surgical strategy. Early correction of genital abnormality may effectively prevent the child present psychological, behavioral onsequences and problems in family and society.

  12. Serotypes, Virulence Factors, and Antimicrobial Susceptibilities of Vaginal and Fecal Isolates of Escherichia coli from Giant Pandas

    OpenAIRE

    Wang, Xin; Yan, Qigui; Xia, Xiaodong; Zhang, Yanming; Li, Desheng; Wang, Chengdong; Chen, Shijie; Hou, Rong

    2013-01-01

    Although Escherichia coli typically colonizes the intestinal tract and vagina of giant pandas, it has caused enteric and systemic disease in giant pandas and greatly impacts the health and survival of this endangered species. In order to understand the distribution and characteristics of E. coli from giant pandas, 67 fecal and 30 vaginal E. coli isolates from 21 giant pandas were characterized for O serogroups, phylogenetic groups, antimicrobial susceptibilities, and pulsed-field gel electrop...

  13. Malformations in a cohort of 284 women with Mayer-Rokitansky-Küster-Hauser syndrome (MRKH

    Directory of Open Access Journals (Sweden)

    Oppelt Patricia G

    2012-08-01

    Full Text Available Abstract Background The aim of this retrospective study was to describe the spectrum of genital and associated malformations in women with Mayer-Rokitansky-Küster-Hauser syndrome using evaluated diagnostic procedures and the Vagina Cervix Uterus Adnex – associated Malformation classification system (VCUAM. Methods 290 women with MRKH syndrome were clinically evaluated with using clinical examinations, abdominal and perineal/rectal ultrasound, MRI, and laparoscopy. Results Classification of female genital malformation according to the Vagina Cervix Uterus Adnex – associated Malformation classification system was possible in 284 women (97.9%. Complete atresia of Vagina (V5b and bilateral atresia of Cervix (C2b were found in 284 patients (100%. Uterus: bilateral rudimentary or a plastic uterine horns were found in 239 women (84.2%. Adnexa: normal Adnexa were found in 248 women (87.3%. Malformations: associated malformations were found in 126 of 282 evaluable women (44.7%, 84 women (29.6% had malformations of the renal system. Of 284 women with Mayer-Rokitansky-Küster-Hauser syndrome 212 women (74.7% could be classified as V5bC2bU4bA0. The most frequent classification was V5bC2bU4bA0M0 (46.8% diagnosed in 133 of 284 women. Conclusions Complete atresia of vagina and cervix were found in all patients, variable malformations were found with uterus and adnexa. A variety of associated malformations were present, predominantly of the renal system. It is therefore recommended that all patients with genital malformations should be evaluated for renal abnormalities.

  14. Diseño, construcción y uso de aplicador vaginal intracavitario multicanal periférico para braquiterapia / Design, construction, and use of peripheral multichannel intracavitary vaginal applicator for brachytherapy

    Scientific Electronic Library Online (English)

    Manuel, Vega Hernández; Rodolfo, Alfonso Laguardia.

    2006-12-01

    Full Text Available La braquiterapia vaginal intracavitaria es frecuentemente administrada con aplicadores cilíndricos de un solo canal con fuentes HDR. El cilindro multicanal (8 canales) vaginal intracavitario permite el tratamiento preferencial de una parte de la mucosa vaginal, se se desarrolla para perfeccionar y a [...] mpliar la capacidad de la braquiterapia intracavitaria. El aplicador permite activar los canales que se entienden útiles, con longitudes variables, para irradiar volúmenes blancos de la vagina, evitando sobreirradiar las regiones sanas. Se obtiene un gradiente de dosis en la superficie del aplicador vaginal multicanal periférico favorable al tratamiento de lesiones superficiales de la mucosa vaginal, con lo que se disminuye las dosis de recto en el orden del 12 %. Se realizó este estudio con el objetivo de demostrar la utilidad del uso de aplicadores multicanales en vagina y recto, se expresaron los resultados de la construcción de aplicadores y sus características Abstract in english The intracavitary vaginal brachytherapy is often administered using single-channel cylindrical applicators with HDR sources. The intracavitary vaginal multichannel cylinder (8 channels) allows the preferential treatment of a part of the vaginal mucosa, and it is developed to improve and to widen the [...] intracavitary brachytherapy capacity. The applicator makes possible to activate channels considered useful, with variable lengths, to irradiate the target volumes of the vagina, avoiding the overirradiation of the healthy regions. A dose gradient is achieved in the surface of the peripheral multichannel vaginal applicator favouring the treatment of the superficial injuries of the vaginal mucosa, dropping the dose of the rectum by 12 %. This study was undertaken to demonstrate the usefulness of the multichannel applicators in the vagina and rectum. The results of the construction of applicators and their characteristics were explained

  15. [Surprise in abrasion diagnostics].

    Science.gov (United States)

    Kellner, U; Kellner, A; Cirkel, U

    2015-05-01

    Typical localizations of gynecological squamous cell carcinomas are the cervix, vulva and vagina and are therefore not uncommonly diagnosed in curettages. A differentiation from reactive hyperplastic alterations with a possible invasiveness in samples taken from the surface of the special type of well-differentiated verrucous squamous cell carcinoma can be difficult. This pitfall of such a tumor is presented in the case described here with corresponding diagnostic difficulties. PMID:25941098

  16. Estrogen Alters Remodeling of the Vaginal Wall after Surgical Injury in Guinea Pigs1

    OpenAIRE

    BALGOBIN, Sunil; Montoya, T. Ignacio; Shi, Haolin; Acevedo, Jesus F.; Keller, Patrick W.; Riegel, Matthew; Clifford Y. Wai; Word, Ruth Ann

    2013-01-01

    Loss of pelvic organ support (i.e., pelvic organ prolapse) is common in menopausal women. Surgical reconstruction of pelvic organ prolapse is plagued with high failure rates. The objective of this study was to determine the effects of estrogen on biomechanical properties, lysyl oxidase (LOX), collagen content, and histomorphology of the vagina with or without surgical injury. Nulliparous ovariectomized guinea pigs were treated systemically with either 50 ?g/kg/day estradiol (E2,) or vehicle. ...

  17. Potentialities of intracavitary gamma-therapy with AGAT-BU unit

    International Nuclear Information System (INIS)

    Results of the use of a new AGAT-BU unit for intracavitary gamma-therapy of 365 patients with malignant tumors of cervix uteri, corpus uteri, vagina, esophagus, rectum, stomatopharynx, trachea are presented. Methods intracavitary irradiation of endotrachial and endobronchial malignant tumors using AGAT-BU unit are first developed in the USSR. One of AGAT-BU unit advantages is decrease of radiation reactions and complications during combined radiotherapy. AGAT-BU unit radiative-technical data are presented

  18. Gastromermis cordobensis n. sp. (Nematoda: Mermithidae) parasitizing Simulium lahillei Patterson & Shannon (Diptera: Simuliidae) in Argentina

    OpenAIRE

    Camino, Nora B.

    1991-01-01

    Gastromermis cordobensis n. sp (Nematoda: Mermithidae) a parasite of larvae of the blackfly Simulium lahillei Paterson & Shannon (Diptera: Simuliidae) in Argentina, is described. Diagnostic characters of this species include a mouth ventrlly shifted; six cephalic papillae; eigh hypodermal chords; small and pear shaped amphids; a long and S-shaped vagina; a singl spicule, which is long, has non-uniform walls, and a tip with sculpture; three rows of genital papillae, the middle one with 18 pre-...

  19. Two new mermithidis (Nematoda: Mermithidae) parasites of Simulium wolffhuegeli Roubaud and S. jujuyense (Paterson & Shannon) (Diptera: Simuliidae) in Argentina

    OpenAIRE

    Camino, Nora B.

    1993-01-01

    Two new species of mermithids (Nematoda: Mermithidae), Gastromermis doloresi n. sp. a parasite of Simulium wolffhuegeli Roubaud and Hydromermis doloresi n. sp. a parasite of S. jujuyense (Paterson & Shannon) from Córdoba, Argentina, are described and illustrated. G. doloresi n. sp. is characterized by having medium sized, pear-shaped and oval amphids, eight hypodermal chords all around the body, cylindrical S-shaped vagina, single long spicule 528 [mi]m, whith teh sculpture tip, three rows o...

  20. A new Thelastomatidae, Oryctophila bonaerensis sp. nov. (Nematoda) parasite of curculionid beetle larvae of Prosalbus rufus (Coleoptera: Curculionidae) from Argentina

    OpenAIRE

    Camino, Nora B.; María Fernanda Achinelly

    2011-01-01

    Oryctophila bonaerensis sp. nov. parasitizing curculionid beetle larvae from Argentina, is described and illustrated. The species is characterized by a prominent genital cone and a short and filiform tail appendage. Female with vulva at midlenght of body, vagina long, S-shaped, monodelphic, opistodelphic. Male with one club-shaped spicule. Genital papillae arranged as follows: one pair of large preanal papillae and three pairs of postanal papillae of various sizes: a pair of medium sized papi...

  1. Hexamermis paranaense new species (Nematoda, Mermithidae): a parasite of Diloboderus abderus (Coleoptera, Scarabaeidae) in Argentina Hexamermis paranaense sp. nov. (Nematoda, Mermithidae): parasito de Diloboderus abderus (Coleoptera, Scarabaeidae) en Argentina

    OpenAIRE

    María Fernanda Achinelly; Nora Beatriz Camino

    2008-01-01

    A new species, Hexamermis paranaense n. sp. (Nematoda, Mermithidae), a parasite of larvae of Diloboderus abderus Sturm, 1826 (Coleoptera, Scarabaeidae) is described and illustrated. This new species is characterized by amphids small, amphidial opening pocket-shaped, the anterior portion of the vagina muscularized and slightly protruding with a descending branch forming a loop before joining the uterus, and three rows of genital papillae: the ventrolateral divided in two rows with eight papill...

  2. A Comparison of Lower Genital Tract Glycogen and Lactic Acid Levels in Women and Macaques: Implications for HIV and SIV Susceptibility

    OpenAIRE

    Mirmonsef, Paria; Gilbert, Douglas; Veazey, Ronald S.; Wang, Jing; Kendrick, Sabrina R.; Spear, Gregory T.

    2012-01-01

    Understanding factors that affect heterosexual transmission of HIV in women is of great importance. Lactobacilli in the lower genital tract of women utilize glycogen in vaginal epithelial cells as an energy source and produce lactic acid. The resultant vaginal acidity is believed to provide protection against HIV infection. Conversely, bacterial vaginosis (BV) is characterized by less lactic acid and a higher pH, and is associated with increased susceptibility to HIV infection. Because vagina...

  3. Antibiotic Therapy for Premature Rupture of Membranes and Preterm Labor and Effect on Fetal Outcome

    OpenAIRE

    Seelbach-goebel, B.

    2013-01-01

    In Germany almost 10?% of children are born before the end of 37th week of gestation. In at least one quarter of these cases, ascending infection of the vagina plays a causative role, particularly during the early weeks of gestation. If, in addition to the decidua, the amniotic membrane, amniotic fluid and the umbilical cord are also affected, infection not only triggers uterine contractions and premature rupture of membranes but also initiates a systemic inflammatory reac...

  4. Isolation and identification of pathogenic bacteria from genital tract of the Arabian mares affected with genital tract infection and antimicrobial sensitivity

    OpenAIRE

    Al-abidy, H. F.

    2010-01-01

    This study was conducted for isolation and identification of the pathogenic bacteria presented in the genital tract infectionof the Arabian mares, and shows the anti microbial sensitivity. The study included 75 samples taken from infected maressuffering from genital tract infection diagnosed on the basis of case history and clinical signs which included bloody purulentdischarge ranched from yellow to green in colure, fetid oder with congested and oedematous vagina and from some abortioncases,...

  5. Partial vaginismus : definition, symptoms and treatment

    OpenAIRE

    Engman, Maria

    2007-01-01

    Vaginismus is a sexual pain disorder, where spasm of musculature of the outer third of the vagina interferes with intercourse. Vaginismus exists in two forms: total vaginismus, where intercourse is impossible, and the more seldom described partial vaginismus, in which intercourse is possible but painful. The aim of the thesis was to develop a useful definition of partial vaginismus for both clinical and scientific purposes; to describe the prevalence of partial vaginismus among women with sup...

  6. A rare case of penetrating rectal injury.

    Science.gov (United States)

    Thomas, Vijy Paul

    2013-06-01

    Penetrating injuries of the colon and rectum have been reported earlier and are often associated with injuries of adjacent viscera such as bladder, uterus or vagina, prostate and seminal vesicles as well as iliac vessels. But this case is rare not only regarding the mechanism of injury but also with respect to the depth of penetration, with the foreign body having almost reached the thorax after entry through the anal orifice. PMID:24426439

  7. Randomized controlled trial of probiotics for the prevention of spontaneous preterm delivery associated with intrauterine infection: study protocol

    OpenAIRE

    Savastano Clarisse; Batista Maria; Camacho Karla G; Braga Alcione; Rezende Maria R; Alves Mariane B; Moreira Maria; Krauss-Silva Leticia; Almada-Horta Antonio; Guerra Fernando

    2010-01-01

    Abstract Background Spontaneous preterm deliveries that occur before the 34th week of gestation, and particularly before the 32nd week of gestation, have been strongly associated to intrauterine infection, ascending from vagina, and represent the largest portion of neonatal deaths and neurological problems. Bacterial vaginosis, characterized by a diminished or absent flora of lactobacilli and increased colonization of several anaerobic or facultative microorganisms, increases two times the ri...

  8. Vaginal Microbiota and the Use of Probiotics

    OpenAIRE

    Cribby, Sarah; Taylor, Michelle; Reid, Gregor

    2008-01-01

    The human vagina is inhabited by a range of microbes from a pool of over 50 species. Lactobacilli are the most common, particularly in healthy women. The microbiota can change composition rapidly, for reasons that are not fully clear. This can lead to infection or to a state in which organisms with pathogenic potential coexist with other commensals. The most common urogenital infection in premenopausal women is bacterial vaginosis (BV), a condition characterized by a depletion of lactobacilli...

  9. PROBIOTIC PROPERTIES OF VAGINAL LACTIC ACID BACTERIA SELECTED FOR HARMONIZATION OF MICROENVIRONMENT OF REPRODUCTIVE APPARATUS

    OpenAIRE

    Eva Styková; Igor Valocký; František Novotný; Peter Guba

    2012-01-01

    The aim of this study was isolation and screening of probiotic properties of Lactobacillus strains isolated from the vagina of heifers and cows with healthy reproductive apparatus. Initially tested properties were low pH tolerance, growth at different temperature, autoaggregation, fast growth and acid production. Strains were further tested for adherence to vaginal mucus. Negative selection was used and strains that did not meet tested criterion were excluded. From 244 samples taken from 122 ...

  10. The degree of serum estradiol decline in early and midluteal phase had no adverse effect on IVF/ICSI outcome

    OpenAIRE

    Narvekar Sachin; Gupta Neelima; Shetty Nivedita; Kottur Anu; Srinivas M; Rao Kamini

    2010-01-01

    Background: Estradiol levels fall rapidly in the luteal phase of ART cycles. So far, the effect of this estradiol decline on pregnancy outcome has remained controversial. Aim: To study the effect of early and midluteal estradiol decline on pregnancy and miscarriage rate. We also sought to determine whether estradiol fall was related to increased risk of bleeding per vagina in the first trimester among pregnancies which crossed 12 weeks. Setting: Tertiary Assisted conception center. Desig...

  11. A NEW SPECIES PHOREIOBOTHRIUM GAWALI FROM CARCHARIAS ACUTUS (MULLER AND HENLE, 1906 AT BANKOT, RATNAGIRI M.S. INDIA

    Directory of Open Access Journals (Sweden)

    Pawar LB*, Shewale SS, Patil DN and RR Dandwate

    2013-08-01

    Full Text Available A new species of Cestode Phoreiobothrium gawali was erected form the marine fish Carcharias acutus (Muller and Henle, 1841 collected from Bankot, Ratnagiri (West coast of India. We have described this new species in the genus Phoreiobothrium (LINTON 1989 We found P. gawali different from other species in body measurement, scolex length, breadth, sucker, neck, testes, ovary, vagina, genital pore, vitellaria, host and locality.

  12. Tumor de la vulva, vulvectomía radical / Vulvar tumor, total vulvectomy

    Scientific Electronic Library Online (English)

    Asbel Alfredo, Vicente de la Cruz; Maribel Lissette, Vicente Medina; Ada Hilda, de la Concepción de la Peña.

    2011-09-01

    Full Text Available Los tumores de la vulva no son una rareza entre los cánceres que afectan a las féminas, pero tampoco son de los más frecuentes. Se presenta el caso de una mujer de 59 años, que en el año 2000 se le diagnostica carcinoma epidermoide del clítoris, en 2004 se vuelve a intervenir por recidiva tumoral, y [...] en 2009 acude a nuestra consulta nuevamente y es cuando se decide realizarle vulvectomía y resección de vagina y todo el sistema ginecológico. Concluyó la intervención con una talla vesical extraperitoneal. El tumor se extiende hasta la porción inicial de la vagina y uretra. Se trata de un tumor maligno, bien diferenciado, que se ha comportado en una forma no habitual, con recidivas locales, cuando en apariencia el tumor había sido resecado en toda su extensión, y en esta última oportunidad, a pesar de ser un estadio avanzado, no hemos encontrado metástasis ni multicentricidad del tumor. La evolución posoperatoria fue sin complicaciones y se dio de alta al quinto día. Abstract in english The vulvar tumors are not uncommon among the different types of cancer involving females, but neither are the more frequent ones. This is the case of a female aged 59 that in 2000 is diagnosed with epidermoid carcinoma of clitoris, in 2004 is re-operated on by tumor relapse, and in 2009 she came aga [...] in to our consultation and a vulvectomy, vagina resection and all gynecological system are carried out. Intervention concluded with an extraperitoneal vesical cutting. The tumor extends up to the initial portion of vagina and urethra. It is a malignant and well-differentiated tumor behaved in non habitual way with local relapses, when apparently the tumor was resected in all its extent, and in this last change, despite and advanced stage, there were neither tumor metastases nor multi-centralization. The postoperative course was free of complications receiving the discharge at fifth day.

  13. VALIDEZ DE LA PRUEBA DE HISTERECTOMÍA VAGINAL EN PACIENTES CON INDICACIÓN DE VÍA ABDOMINAL MANDATORIA

    Directory of Open Access Journals (Sweden)

    Juan Riquelme P

    2010-01-01

    Full Text Available Objetivo: Evaluar la histerectomía vaginal en la resolución de patología uterina benigna, en casos que habitualmente se resuelven por histerectomía abdominal. Método: Estudio prospectivo en 68 pacientes sometidas a histerectomía vaginal en el Servicio de Ginecología del Hospital Claudio Vicuña, de San Antonio, entre junio de 2003 a junio de 2009. Son pacientes sin partos vaginales, algunas nuligestas, la mayoría con cicatrices de cesárea o historia de cirugía pélvica previa. Se separan en dos grupos, uno de dificultad moderada (DM (útero móvil, vagina >2 dedos de diámetro, fondos de saco bien conformados y otro de dificultad severa (DS (útero fijo, vagina Objective: To assess vaginal hysterectomy in benign uterine pathology resolution in cases who are usually resolved by abdominal hysterectomy. Method: We studied, prospectively, 68 patients that were operated by vaginal hysterectomy between june 2003 to june 2009 in the Gynecology Service at Claudio Vicuña Hospital, San Antonio. Most of the patients have history of prior cesarean section or pelvic surgery, but no one has had vaginal deliveries, inclusive, some of them, have no history of previous pregnancies. The patients were separated into two groups, moderate difficulty (MD: composed by patients with uterus conserved motility, vagina >2 fingers diameter, well conserved cul de sac, and severe difficulty (SD: composed by patients with none uterine motility, vagina <2 fingers diameter or fat cul de sac. Results: We did not observed statistically signifcant differences in age, number of prior cesarean sections or pelvic surgeries, estimated uterine size, bladder injury, nor abdominal conversion, but there was significant differences in operative time and need of morcelation, being greater in SD patients. It is important to notice the absent of major and minor complications in 93% of the patients. Conclusion: Our results are meant to demystify the objections for vaginal route, including the patients with extreme difficulty.

  14. 18F-Fluorodeoxyglucose PET/CT in a Patient with Esophageal and Genital Leiomyomatosis

    International Nuclear Information System (INIS)

    Diffuse esophageal leiomyomatosis is a rare benign tumor, which can be associated with leiomyoma in female genital tracts involving the uterus, vagina, and vulva. Alport syndrome, an inherited disorder that includes the kidneys, eyes, and sensorineural hearing loss, is also rarely associated with these multiple leiomyomatosis. In our case, 18F-fluoroseoxyglucose positron emission tomography/ computed tomography was used to distinguish esophageal and genital leiomyomatosis from malignant masses

  15. Vaginal Versus Sublingual Misoprostol for Labor Induction at Term and Post Term: a Randomized Prospective Study

    OpenAIRE

    Ayati, Sedigheh; Vahidroodsari, Fatemeh; Farshidi, Farnoosh; Shahabian, Masoud; Afzal Aghaee, Monavar

    2014-01-01

    We want to compare the efficacy and safety of vaginal versus sublingual misoprostol for cervical ripening and induction of labor. This randomized clinical trial was performed on 140 women with medical or obstetric indications for labor induction. The patients were randomly divided into two groups: vaginal and sublingual administration of misoprostol. In first group, 25 µg misoprostol was placed in the posterior fornix of the vagina and second group received 25 µg misoprostol sublingually, eve...

  16. Comparative genomic and functional analysis of 100 Lactobacillus rhamnosus strains and their comparison with strain GG

    OpenAIRE

    Douillard, F. P.; Ribbera, A.; Kant, R.; Pietila?, T. E.; Ja?rvinen, H. M.; Messing, M.; Randazzo, C. L.; Paulin, L.; Laine, P. K.; Ritari, J.; Caggia, C.; La?hteinen, T.; Brouns, S. J. J.; Satokari, R. M.; Ossowski, I.

    2013-01-01

    Lactobacillus rhamnosus is a lactic acid bacterium that is found in a large variety of ecological habitats, including artisanal and industrial dairy products, the oral cavity, intestinal tract or vagina. To gain insights into the genetic complexity and ecological versatility of the species L. rhamnosus, we examined the genomes and phenotypes of 100 L. rhamnosus strains isolated from diverse sources. The genomes of 100 L. rhamnosus strains were mapped onto the L. rhamnosus GG reference genome....

  17. The Role of the Aryl Hydrocarbon Receptor in the Female Reproductive System

    OpenAIRE

    Hernández-Ochoa, Isabel; Karman, Bethany N.; Flaws, Jodi A

    2008-01-01

    In recent years, many studies have emphasized how changes in aryl hydrocarbon receptor (AHR)-mediated gene expression result in biological effects, raising interest in this receptor as a regulator of normal biological function. This review focuses on what is known about the role of the AHR in the female reproductive system, which includes the ovaries, fallopian tubes or oviduct, uterus and vagina. This review also focuses on the role of the AHR in reproductive outcomes such as cyclicity, sene...

  18. A New Cestode Moniezia Vanamalae N.SP. (Eucestoda : Anoplocephalidae) From Capra Hircus

    OpenAIRE

    Patil, P. S.

    2012-01-01

    The scolex of Moniezia vanamalae n.sp. is large, broad anteriorly, narrow posteriorly, suckers medium, oval arranged in two pairs, one pair in each half of the scolex. Mature proglottids are big, broader than long, each with double set of reproductive organs, testes follicular, small, round 210-215(211), cirrus pouch in each side, cirrus is thin, slightly coiled, ovary on each side large, globular with irregular margin,vagina is a thin tube situated posterior to the cirrus pouch,...

  19. A new species of Anoplodiscus (Monogenea: Anoplodiscidae) parasitic on Pagrus pagrus (Osteichthyes: Sparidae) from the coastal zone of the State of Rio de Janeiro, Brazil

    Scientific Electronic Library Online (English)

    Aline R, Paraguassú; José L, Luque; Dimitri R, Alves.

    1197-11-01

    Full Text Available A new species of Anoplodiscus (Monogenea, Anoplodiscidae), parasitic on gills of the red porgy, Pagrus pagrus, from the coastal zone of the State of Rio de Janeiro, Brazil, is described and illustrated. The new species can be differentiated from the other species of this genus by the shape of the ac [...] cessory piece of the copulatory complex, and the length of the vagina. This is the first record of a species of Anoplodiscus in the Neotropical region.

  20. A new species of Anoplodiscus (Monogenea: Anoplodiscidae) parasitic on Pagrus pagrus (Osteichthyes: Sparidae) from the coastal zone of the State of Rio de Janeiro, Brazil

    OpenAIRE

    Paraguassú Aline R; Luque José L; Alves Dimitri R

    2002-01-01

    A new species of Anoplodiscus (Monogenea, Anoplodiscidae), parasitic on gills of the red porgy, Pagrus pagrus, from the coastal zone of the State of Rio de Janeiro, Brazil, is described and illustrated. The new species can be differentiated from the other species of this genus by the shape of the accessory piece of the copulatory complex, and the length of the vagina. This is the first record of a species of Anoplodiscus in the Neotropical region.