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1

Vagina evaluation by MR imaging  

International Nuclear Information System (INIS)

The author evaluated MR imaging of the vagina under different hormonal stimuli (25 patients) and assessed the role of MR imaging in the evaluation of congenital abnormalities (15 patients), primary (3) and metastatic (5) neoplasms, and reconstructive surgery (3). The findings were confirmed surgically. The appearance of the mucosa and vaginal wall was influenced by hormonal status. The presence of the vagina (45 patients), absence of the vagina (4), and the presence of duplication anomaly (3) were always accurately demonstrated on MR images. Carcinoma and metastases were depicted as tumor interrupting the low intensity signal of the muscular wall of the vagina. In two of three patients who underwent reconstructive surgery, postsurgical perivaginal abscesses developed that were correctly displayed on MR images. The normal and abnormal vaginas were exquisitely shown on MR images. For complicated congenital abnormalities, complications of postreconstructive surgery, and staging of neoplasms, MR imaging should be considered a primary imaging modality

2

Vesicouterine fistula and blind vagina  

International Nuclear Information System (INIS)

A case of vesicouterine fistula with blind vagina following cesarean section for obstructed labor is presented. It was surgically treated by fistulectomy, cervicoplasty and maintenance of bladder and cervical potency by catheterization. Intrauterine synechiae formation was prevented by copper T insertion and oral contraceptive pills. The patient is making uneventful a symptomatic progress planning to conceive. (author)

3

Adenocarcinoma de células claras de la vagina  

Scientific Electronic Library Online (English)

Full Text Available SciELO Chile | Language: Spanish Abstract in spanish Se presenta un caso clínico de adenocarcinoma de células claras de vagina en mujer de 23 años, sin antecedentes de exposición intrauterina a dietilestilbestrol. Se efectuó colpohisterectomía radical, linfadenectomía pélvica completa y ooforopexia bilateral, más radioterapia externa adyuvante (45 Gy) [...] . Sin evidencia de enfermedad a 5 meses de completada su terapia Abstract in english A case of clear cell adenocarcinoma of the vagina in a 23 year old woman, without diethylstilbestrol intrauterine exposure, is presented. The surgical and the radiotherapy treatment are discussed. Without evidence of disease at 5 months follow up. A brief discussion of literature is also provided [...

Rubén, Urrejola S.; Ana María, Carrasco T.; Fernando, Heredia M..

4

Small cell carcinoma of the vagina  

International Nuclear Information System (INIS)

A case of localized small cell neuroendocrine carcinoma of the vagina is reported. The patient was treated with concurrent chemoradiation with significant toxicity but obtained a complete response. Thirteen months after therapy the patient developed distant metastasis and died shortly thereafter. Review of the literature found that patients treated with local therapy alone had a shorter survival and died of systemic disease. As with small cell neuroendocrine carcinomas arising from other sites, systemic relapse remains an important issue that warrants combination therapies, although in pelvic sites this may be associated with an increase in side-effects. Copyright (2000) Blackwell Science Pty Ltd

5

Radiotherapy of malignant tumors of the vagina  

International Nuclear Information System (INIS)

A new method of combined radiotherapy for cancer of the vagina is presented: it includes contact (intracavitary and interstitial) gamma-therapy based on the principle of the manual and automated administration (using the AGAT-B unit) of endostats and low and high activity radiation sources, and gamma irradiation with irregular shaped fields. The problems of fractionation, a choice of required irradiation volumes as well as summary absorbed dose levels are discussed. An analysis of the clinical efficacy was based delayed results. The 5-year survival rate in the general group of patients was 41.2%

6

Radiation therapy for carcinoma of vagina  

Energy Technology Data Exchange (ETDEWEB)

Thirty-four patients with carcinoma of the vagina were treated by radiotherapy at the Hyogo Medical Center for Adults between April 1965 and May 1990. All patients were treated with a combination of external and intracavitary or interstitial irradiation. Twenty-three patients had squamous cell carcinoma, five had adenocarcinoma and two had malignant melanoma. The five-year survival of patients with squamous cell carcinoma was 70% in Stage I (10 patients), 40% in Stage II (seven patients), 50% in Stage III (three patients) and 0% in Stage IV (three patients). Local control was achieved in 72.7% of the patients with squamous cell carcinoma and 60% of those with adenocarcinoma. However, neither of the malignant melanomas was controlled. Five patients had severe complications that required surgical treatment: severe proctitis and small-bowel perforation, ileus, rectal stenosis, vesicovaginal fistula and small-bowel perforation. Local and pelvic failure was noted in three patients. Patients with previous hysterectomy were more likely to develop serious treatment-related complications. (author).

Mieda, Chieko; Hirota, Saeko; Soejima, Toshinori (Hyogo Medical Center for Adults, Akashi (Japan)) (and others)

1993-07-01

7

Adenocarcinoma of the vagina in a patient with gonadal dysgenesis.  

Science.gov (United States)

Adenocarcinoma of the vagina is an uncommon tumor. Many theories have been postulated for its etiology and tissue origin. Its occurrence in young women exposed in utero to diethylstilbestrol has pointed to estrogen influence as a possible etiologic factor. A case of adenocarcinoma of the vagina in a patient with gonadal dysgenesis is presented, and histologic and electron-microscopic observations are discussed. This patient is unique in that development of the vaginal neoplasm occurred in the absence of estrogen influence. PMID:424140

Shingleton, H M; Younger, J B; Beasley, W E; Levy, D; Gore, H; Lawrence, W D

1979-03-01

8

Malignant melanoma of the vagina: CT and MR findings  

International Nuclear Information System (INIS)

We report CT and MR findings in two cases of primary malignant melanoma of the vagina, one arising from cervicovaginal junction mimicking squamous cell carcinoma of the cervix and the other one recurring at vagina after resection. Two cases of malignant melanoma had high-attenuation on CT and high signal intensity on T1-weighted MR images and enhanced well after gadopentetate dimeglumine administration

9

Aggressive angiomyxoma of the vagina: a case report / Angiomiosarcoma agressivo da vagina: relato de caso  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in portuguese O angiomixoma agressivo é tumor raro de tecidos moles, de lento crescimento e que geralmente ocorre na pelve e nas regiões perineais de mulheres em idade reprodutiva, com forte tendência à recorrência local. Devido à sua raridade, ele é frequentemente mal diagnosticado. A exerese cirúrgica é a modal [...] idade principal para o tratamento do angiomixoma agressivo. Descrevemos aqui um caso de angiomixoma vaginal agressivo em mulher de 47 anos de idade, que foi diagnosticado apenas após exame histológico. Descrevemos também a etiologia e apresentação, bem como o diagnóstico e tratamento desse raro tumor. O angiomixoma da vulva e vagina constitui doença rara. Devido à raridade desse tumor e à ausência de elementos diagnósticos, o diagnóstico pré-operatório é difícil, mas deveria ser considerado na presença de qualquer massa na região genital, perianal e pélvica de mulheres em idade reprodutiva. Portanto, esses casos deveriam ser submetidos a propedêutica radiológica completa antes da exerese, uma vez que um pré-diagnóstico pode modificar a modalidade de tratamento e o prognóstico do paciente. Abstract in english Aggressive angiomyxoma is a rare, slow-growing soft tissue tumor that usually arises in the pelvis and perineal regions of women in reproductive age, with a marked tendency to local recurrence. Because of its rarity, it is often initially misdiagnosed. Surgical resection is the main treatment modali [...] ty of aggressive angiomyxoma. We describe a case of a vaginal aggressive angiomyxoma in a 47-year-old woman in which the diagnosis was only made after histological examination. The etiology, presentation, diagnosis and management of this rare tumor are outlined. Angiomyxoma of vulva and vagina refers to a rare disease. Pre-operative diagnosis is difficult due to rarity and absence of diagnostic features, but it should be considered in every mass in genital, perianal and pelvic region in a woman in the reproductive age. Thus, these cases should have complete radiological workup before excision, as pre-diagnosis can change the treatment modality and patient prognosis'.

Cátia, Lourenço; Nuno, Oliveira; Filomena, Ramos; Isabel, Ferreira; Mário, Oliveira.

2013-12-01

10

Radiosterilisation of the vagina in therapeutic doses - does it exist  

International Nuclear Information System (INIS)

The endogenous genital flora is a major source of infections of the female genital tract, especially in patients with cervical or endometrial cancer. Until recently the 'radiosterilisation of the vagina', respectively a prophylactic and/or therapeutic effect of irradiation (external highvoltage as well as intracavitary-radium) concerning infections was postulated in the literature. This theory was disproved in a prospective clinical and bacteriological study covering 48 patients with advanced cervical cancer undergoing primary intracavitary radium-irradiation and 38 patients with inoperable endometrical cancer, undergoing primary iridium-192-afterloading. Following intracavitary radium for cervical cancer some typical nosocomial pathogens like Streptococcus faecalis, Enterobacter, Klebsiella, Proteus and Pseudomonas were isolated significantly more frequently than before treatment. Likewise, the mean number of aerobic bacterial species increased significantly after irradiation. Also primary Ir-192 (afterloading) irradiation did not alter the frequency of isolation of the resident flora in endometrial cancer patients. Therefore, 'radiosterilisation' of the vagina as result of radiotherapy does not exist. (orig.)

11

Nanoparticle-based drug delivery to the vagina: a review.  

Science.gov (United States)

Vaginal drug administration can improve prophylaxis and treatment of many conditions affecting the female reproductive tract, including sexually transmitted diseases, fungal and bacterial infections, and cancer. However, achieving sustained local drug concentrations in the vagina can be challenging, due to the high permeability of the vaginal epithelium and expulsion of conventional soluble drug dosage forms. Nanoparticle-based drug delivery platforms have received considerable attention for vaginal drug delivery, as nanoparticles can provide sustained release, cellular targeting, and even intrinsic antimicrobial or adjuvant properties that can improve the potency and/or efficacy of prophylactic and therapeutic modalities. Here, we review the use of polymeric nanoparticles, liposomes, dendrimers, and inorganic nanoparticles for vaginal drug delivery. Although most of the work toward nanoparticle-based drug delivery in the vagina has been focused on HIV prevention, strategies for treatment and prevention of other sexually transmitted infections, treatment for reproductive tract cancer, and treatment of fungal and bacterial infections are also highlighted. PMID:24830303

Ensign, Laura M; Cone, Richard; Hanes, Justin

2014-09-28

12

Management of radiation injuries of vulva and vagina  

Energy Technology Data Exchange (ETDEWEB)

Background: Acute and late injuries of vulva and vagina are frequent and potentially serious complications in radiotherapy of gynecologic tumors. They still are reported poorly in literature. Methods: Based on a literature search a survey will be given of the modalities, which are used or recommended for prophylaxis or treatment of these radiation injuries. The principles of the different measures will be discussed with available study results. Results: Hygiene measures and the topical application of antimicrobial or granulation stimulating substances, which is mostly based on long standing clinical experience, are the principles of the treatment of acute reactions of vulva and vagina. The topical use of estrogen, which promotes proliferation of epithelium, is generally described in connection with treatment and prophylaxis of late radiation injuries. As a prophylaxis for the late reaction of vaginal stenosis, vaginal dilatation is recommended in literature. Conclusion: With the exception of a few reports on estrogen, there are no data about the effectiveness of the currently used medical substances. The local application of estrogen as prophylaxis of the acute reactions will therefore be examined in a prospective study. (orig.) [Deutsch] Hintergrund: Akute und spaete Reaktionen an Vulva und Vagina sind haeufige und zum Teil schwerwiegende Nebenwirkungen der Strahlentherapie von gynaekologischen Tumoren, auf die in der Literatur kaum eingegangen wird. Methoden: Basierend auf einer umfangreichen Literaturrecherche, werden die Massnahmen, die zur Prophylaxe oder Therapie dieser Strahlenreaktionen zur Verfuegung stehen, systematisch zusammengestellt und, soweit verfuegbar, mit Ergebnissen aus Studien diskutiert. Ergebnisse: Hygienemassnahmen und die auf klinischen Erfahrungswerten basierende lokale Anwendung einer Vielzahl von mehr oder weniger antimikrobiell wirkenden oder granulationsfoerdernden Substanzen lassen sich als Grundprinzipien der Behandlung von akuten Reaktionen an Vulva und Vagina erkennen. Der Einsatz von lokalen Oestrogenapplikationen, die die hormonabhaengige Proliferation des Epithels ausnutzen, wird ueberwiegend im Zusammenhang mit Therapie und Prophylaxe von radiogenen Spaetfolgen beschrieben. Als eine Art der Prophylaxe von Spaetreaktionen in Form der Vaginalstenose hat sich die Empfehlung der vaginalen Dilatation etabliert. Schlussfolgerungen: Mit Ausnahme von einigen Arbeiten zu Oestrogen gibt es keine Daten ueber die Wirksamkeit der eingesetzten Substanzen. Die lokale Oestrogenapplikation zur Prophylaxe der akuten Strahlenreaktionen wird daher in einer prospektiven Studie untersucht werden. (orig.)

Fraunholz, I.B.; Schopohl, B.; Boettcher, H.D. [Klinik fuer Strahlentherapie und Onkologie, Johann-Wolfgang-Goethe-Universitaet Frankfurt am Main (Germany)

1998-11-01

13

Management of radiation injuries of vulva and vagina  

International Nuclear Information System (INIS)

Background: Acute and late injuries of vulva and vagina are frequent and potentially serious complications in radiotherapy of gynecologic tumors. They still are reported poorly in literature. Methods: Based on a literature search a survey will be given of the modalities, which are used or recommended for prophylaxis or treatment of these radiation injuries. The principles of the different measures will be discussed with available study results. Results: Hygiene measures and the topical application of antimicrobial or granulation stimulating substances, which is mostly based on long standing clinical experience, are the principles of the treatment of acute reactions of vulva and vagina. The topical use of estrogen, which promotes proliferation of epithelium, is generally described in connection with treatment and prophylaxis of late radiation injuries. As a prophylaxis for the late reaction of vaginal stenosis, vaginal dilatation is recommended in literature. Conclusion: With the exception of a few reports on estrogen, there are no data about the effectiveness of the currently used medical substances. The local application of estrogen as prophylaxis of the acute reactions will therefore be examined in a prospective study. (orig.)

14

Definitive radiation therapy for squamous cell carcinoma of the vagina  

International Nuclear Information System (INIS)

Purpose: To evaluate outcome and describe clinical treatment guidelines for patients with primary squamous cell carcinoma of the vagina treated with definitive radiation therapy. Methods and Materials: Between 1970 and 2000, a total of 193 patients were treated with definitive radiation therapy for squamous cell carcinoma of the vagina at The University of Texas M. D. Anderson Cancer Center. The patients' medical records were reviewed to obtain information about patient, tumor, and treatment characteristics, as well as outcome and patterns of recurrence. Surviving patients were followed for a median of 137 months. Survival rates were calculated using the Kaplan-Meier method, with differences assessed using log-rank tests. Results: Disease-specific survival (DSS) and pelvic disease control rates correlated with International Federation of Gynecology and Obstetrics (FIGO) stage and tumor size. At 5 years, DSS rates were 85% for the 50 patients with Stage I, 78% for the 97 patients with Stage II, and 58% for the 46 patients with Stage III-IVA disease (p = 0.0013). Five-year DSS rates were 82% and 60% for patients with tumors ?4 cm or >4 cm, respectively (p = 0.0001). At 5 years, pelvic disease control rates were 86% for Stage I, 84% for Stage II, and 71% for Stage III-IVA (p = 0.027). The predominant mode of relapse after definitive radiation therapy was local-regional (68% and 83%, respectively, for patients with stages I-II or III-IVA disease). The incidence of majorIII-IVA disease). The incidence of major complications was correlated with FIGO stage; at 5 years, the rates of major complications were 4% for Stage I, 9% for Stage II, and 21% for Stage III-IVA (p < 0.01). Conclusions: Excellent outcomes can be achieved with definitive radiation therapy for invasive squamous cell carcinoma of the vagina. However, to achieve these results, treatment must be individualized according to the site and size of the tumor at presentation and the response to initial external-beam radiation therapy. Brachytherapy plays an important role in the treatment of many vaginal cancers but should be carefully selected and applied to obtain optimal coverage of the target volume

15

Particles translocate from the vagina to the oviducts and beyond  

Energy Technology Data Exchange (ETDEWEB)

To investigate whether particles deposited in the vagina translocate to the oviducts, 0.3 ml of a 4% bone black suspension was deposited in the posterior vaginal fornix of each of five cynomolgus monkeys (Macaca fascicularis) during their mid-menstrual cycle. Simultaneously, each animal received 10 units of oxytocin by intramuscular injection. The oviducts of three animals were removed 1 hr after administration of the bone black, while those of the remaining two animals were removed 72 hr after dosing. The removed oviducts were flushed with Hank's solution and then with collagenase solution. The solutions were collected in clean vials and filtered. The filters were examined for bone black particles by light microscopy, as were filters through which solution blanks (negative controls) had been passed. Particles resembling bone black were found on all filters. There were no appreciable differences in the number or shape of these particles between the solution-blank filters and the oviduct-flush filters. The particles on both the solution-blank filters and on the oviduct-flush filters probably originated from environmental contamination by ubiquitous carbon particles. While these results suggested that no translocation took place, translocation could not be ruled out with certainty in the absence of quantitative analyses. A more definitive pilot study was then conducted with two dosed monkeys and one control, using talc labelled by neutron activation to circumvent the problem of environmental contamination. Gamma-Ray analysis of tissue and peritoneal lavage samples for the radionuclides /sup 46/Sc, /sup 59/Fe and /sup 60/Co indicated that no measurable quantities (i.e. greater than 0.5 micrograms) of talc translocated from the deposition site in the vagina to the uterine cavity and beyond.

Wehner, A.P.; Hall, A.S.; Weller, R.E.; Lepel, E.A.; Schirmer, R.E.

1985-03-01

16

Primary Small Cell Neuroendocrine Carcinoma of Vagina: A Rare Case Report  

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Primary small cell neuroendocrine carcinoma of vagina is an extremely rare disease. There have been only 26 previously reported cases in literature. Here, we report a case of primary small cell neuroendocrine carcinoma of vagina. Immunohistochemistry (IHC) showed tumor cells positive for synaptophysin, chromogranin, and neuron-specific enolase (NSE).

Parekh, Malay N.; Kapapura, Dhiren V.; Bhalodia, Jignasa N.

2011-01-01

17

The irradiation tolerance dose of the proximal vagina  

International Nuclear Information System (INIS)

Purpose: The purpose of this investigation was to determine the irradiation tolerance level and complication rates of the proximal vagina to combined external irradiation and low dose rate (LDR) brachytherapy. Also, the mucosal tolerance for fractionated high dose rate (HDR) brachytherapy is further projected based on the biological equivalent dose (BED) of LDR for an acceptable complication rate. Materials and methods: Two hundred seventy-four patients with stages I-IV cervical carcinoma treated with irradiation therapy alone from 1987 to 1997 were retrospectively reviewed for radiation-associated late sequelae of the proximal vagina. All patients received LDR brachytherapy and 95% also received external pelvic irradiation. Follow-up ranged from 15 to 126 months (median, 43 months). The proximal vagina mucosa dose from a single ovoid (single source) or from both ovoids plus the tandem (all sources), together with the external irradiation dose, were used to derive the probability of a complication using the maximum likelihood logistic regression technique. The BED based on the linear-quadratic model was used to compute the corresponding tolerance levels for LDR or HDR brachytherapy. Results: Grades 1 and 2 complications occurred in 10.6% of patients and Grade 3 complications occurred in 3.6%. There were no Grade 4 complications. Complications occurred from 3 to 71 months (median, 7 months) after completion of irradiation, with over 60% occurring in the first year. By over 60% occurring in the first year. By logistic regression analysis, both the mucosal dose from a single ovoid or that from all sources, combined with the external irradiation dose, demonstrate a statistically significant fit to the dose response complication curves (both with P=0.016). The single source dose was highly correlated with the all source dose with a cross-correlation coefficient 0.93. The all source dose was approximately 1.4 times the single source dose. Over the LDR brachytherapy dose rate range, the complication rate was relatively stable to small variations of the underlying tumor biological characteristics and the dose rate. The complication rates change approximately an absolute 1% over the range of the alpha-beta ratio (?/?) from 2 to 4 Gy and repair constant (?) of 0.46/h to 0.60/h. The complication rates increased an absolute 2% over the mucosa dose rate from 1.75 to 3.50 Gy/h. They markedly increased as the dose rate increased above 3.00 Gy/h as in HDR brachytherapy. The projected HDR Grade 3 tolerance varied from 25 Gy for one fraction to 57 Gy for six fractions in addition to 20 Gy external irradiation for nominal 3-5% complication rates. The traditional LDR tolerance dose of 150 Gy was shown to yield nominal 11% and 4% Grades 1 and 2 and Grade 3 sequelae, respectively. Conclusions: The traditional 150 Gy LDR tolerance dose (single source plus external irradiation) can be relaxed to 175 Gy or equivalently a full mucosal dose of 238 Gy (all sources plus external irradiation) for a nominal 5% Grade 3 complication rate. Higher fractionation is necessary with four to six fractions in HDR therapy for similar rates of sequelae. The mucosal surface dose from a single ovoid, which can be readily computed, remains a convenient tolerance check for treatment planning purposes

18

Normal bacterial flora from vaginas of Criollo Limonero cows.  

Science.gov (United States)

In order to describe the normal bacterial flora in vaginas of Criollo Limonero cows, 51 healthy multiparous cows, at least 90-day postpartum, were selected. Duplicated swabs (N = 102) were taken from the vaginal fornix of cows to perform aerobic and anaerobic cultures as well as conventional biochemical tests. Out of 102 swabs, bacterial growth was obtained in 55 (53.9%) while the remaining 47 (46.1%) did not exhibited any bacterial growth. Of the 55 bacterial growths, 23 (41.8%) were aerobic whereas 32 (58.1%) were anaerobic. Likewise, 29 (52.72%) of bacterial growths were pure and 26 (47.27%) were mixed. Under both aerobic and anaerobic conditions, Gram positive bacteria were predominant (81.82% and 73.08%, respectively) over Gram negative bacteria (18.18% and 26.92%, respectively). Isolated bacteria were Arcanobacterium pyogenes (22.92%), Staphylococcus aureus (15.63%), Staphylococcus coagulase negative (17.71%), Erysipelothrix rhusiopathiae (6.25%), Bacteroides spp. (13.54%), and Peptostreptococcus spp. (7.29%). In conclusion, normal vaginal bacterial flora of Criollo Limonero cows was predominantly Gram positive and included A. pyogenes, S. aureus, coagulase negative Staphylococcus, E. rhusiopathiae, Bacteroides spp., and Peptostreptococcus spp. In Criollo Limonero cattle, adaptive aspects such as development of humoral and physical mechanisms for defense, and bacterial adaptation to host deserve research attention. PMID:21082249

Zambrano-Nava, Sunny; Boscán-Ocando, Julio; Nava, Jexenia

2011-02-01

19

Carcinoma of vagina 10 or more years following pelvic irradiation therapy  

International Nuclear Information System (INIS)

Gynecologic cancer records of 4,238 patients treated between 1956 and 1974 were reviewed. Sixteen patients developed neoplasia in the cervix or vagina 10 or more years following pelvic irradiation. Three patients had squamous carcinoma in situ; the other 13 patients had invasive squamous cancer involving the upper vagina. Only 1.26 percent of invasive carcinoma of the cervix treated by radiation therapy from 1956 to 1966 presented with a late or recurrent or new primary tumor involving the vagina or cervix 10 or more years after primary treatment. The authors conclude that the risk of developing radiation-induced carcinoma in the upper vagina or cervix following pelvic irradiation is low. Follow-up Pap smears are indicated for all patients treated for cervical or vaginal malignancies by radiation therapy in order to detect vaginal neoplasia as well as recurrent carcinoma of the cervix

20

Primary carcinoma of the vagina: Tata Memorial Hospital experience  

International Nuclear Information System (INIS)

Purpose: Carcinoma of the vagina is a rare gynecological malignancy comprising approximately 2% of all the gynecological malignancies. We have analyzed the treatment outcome of the patients treated at the Tata Memorial Hospital from January 1984 to December 1993. Methods and Materials: In this 10-year period, 134 patients of primary vaginal cancers were registered at our hospital. Of these, 75 patients received complete treatment and are analyzed. Results: Disease-free survival (DFS) for the whole group is 50%, and overall survival (OAS) is 60%. Most locoregional recurrences and distant failures are noted in the 2 years following treatment. DFS at 5 years is as follows: Stage I (5 patients), Stage IIA (37 patients), Stage IIB (15 patients), Stage III (14 patients), and Stage IV (4 patients); are 40%, 55%, 60%, 50%, and 25%, respectively. The DFS for patients with complete response (42 patients) to external radiation at 5 years is 68%, with partial response (25 patients) is 35%, and with poor or no response (6 patients) is 18% (p 0.0000). We observed that brachytherapy was an important part of the treatment, and patients who received brachytherapy (59 patients), either with a vaginal intracavitary applicator (30 patients) or interstitial implant (29 patients) had a DFS of 53% and 56%, respectively, while 15 patients who received external radiation alone had a DFS of 30%. Patients receiving brachytherapy within 4 weeks of external radiation had a DFS of 60% as compared to 30% when the interval was more than 4 weeks. Conclusion: The factors indicating prognosis are: site and extent of involvement, presence of lymph nodes at presentation, technique of brachytherapy, and interval between external radiation and brachytherapy

 
 
 
 
21

LASER EN EL TRATAMIENTO DE LA NEOPLASIA INTRAEPITELIAL DE VAGINA  

Scientific Electronic Library Online (English)

Full Text Available SciELO Chile | Language: Spanish Abstract in spanish Objetivo: Presentar la experiencia en el tratamiento de la neoplasia intraepitelial de vagina (VAIN) utilizando el láser de CO2. Método: 19 pacientes con el diagnóstico histológico de VAIN fueron tratadas con esta técnica. Se utilizó un diámetro del punto de helio-neón de 1,5 a 2 mm y un poder de de [...] nsidad de 400 a 500 W/cm². Toda la lesión detectable más un margen de al menos 5 mm de tejido circundante aparentemente normal fueron vaporizados a una profundidad de 2 mm. Resultados: 12 de las 14 pacientes evaluables lograron una respuesta completa inicial (86%), de éstas 12 hubo 2 recidivas posteriores (17%), obteniendo una curación en 10 de las 14 evaluables (71%). No hubo complicaciones y se preservó una función vaginal normal. Conclusión: La vaporización con láser es una buena modalidad terapéutica en VAIN, particularmente en mujeres jóvenes en que se ha descartado razonablemente la coexistencia de cáncer invasor Abstract in english Objective: To describe our experience in the treatment of vaginal intra-epithelial neoplasia (VAIN) with the use of CO2 laser. Method: Nineteen patients with the diagnosis of VAIN were treated by this technique. We used a spot size of 1.5 to 2 mm and a power density of 400 to 500 W/cm². The entire l [...] esion in addition to at least a 5 mm margin of adjacent tissue were vaporized to a depth of 2 mm. Results: 12 of 14 evaluable patients had an initial complete response (86%), of these 12, there were 2 recurrences (17%), obtaining a 71% cure rate (10/14). There were no complications and preservation of normal vaginal function. Conclusion: Laser vaporization is a very good treatment modality, particularly in young women in whom the co-existence of invasive malignancy has been ruled out

Roberto, Yazigi I; Tulio, Rodríguez A; Luis, Contreras M.

22

Phagocytosis of spermatozoa by epithelial cells in the vagina of the lizard Hemidactylus mabouia (Reptilia, Squamata).  

Science.gov (United States)

Hemidactylus mabouia is an Africa oviparous lizard that is now distributed on other continents and has been introduced to Brazil. In the majority of reptiles, the females have the ability to store spermatozoa in specialized regions of the genital tract. Considering that in H. mabouia the storage of spermatozoa is restricted to the region of the uterine tube, in this study we utilized optical and transmission electron microscopy to investigate the processes related to the large number of spermatozoa in the vagina. Although it was possible to visualize spermatozoa in the vagina, an ultrastructural analysis of the region revealed that significant phagocytosis occurs, which is mediated by the epithelial cells. Such a process indicates that the anterior portion of the vagina is related to the elimination of supernumerary or deficient spermatozoa and not storage. PMID:21185731

Nogueira, Katiane de Oliveira Pinto Coelho; Araújo, Vinícius Albano; Rodrigues Sartori, Sirlene Souza; Neves, Clóvis Andrade

2011-07-01

23

Endodermal sinus tumor of the vagina in children: A report of two cases  

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Full Text Available Malignant tumors of the vagina in infants and children are rare, with primary germ cell tumor (endodermal sinus tumor [EST] being rarer, which carries a dismal prognosis. This tumor is often clinically mistaken as botryoid rhabdomyosarcoma and, on histopathological examination, is often misdiagnosed as clear cell adenocarcinoma. Two cases of EST of the vagina in infants aged 9 and 17 months are reported. Both the patients presented with bleeding per vagina and clinically and by ultrasonography were diagnosed as sarcoma botryoides. Both were diagnosed as primary yolk sac tumors. The serum alfa fetoprotein (AFP level was 4325 and 9328 ng/ml, respectively. One patient aged 9 months expired 2 months after receiving chemotherapy. The other, aged 17 months, was given chemotherapy followed by surgery with reduction of the AFP levels.

Gangopadhyay Mimi

2009-07-01

24

Endodermal sinus tumor of the vagina in children: a report of two cases.  

Science.gov (United States)

Malignant tumors of the vagina in infants and children are rare, with primary germ cell tumor (endodermal sinus tumor [EST]) being rarer, which carries a dismal prognosis. This tumor is often clinically mistaken as botryoid rhabdomyosarcoma and, on histopathological examination, is often misdiagnosed as clear cell adenocarcinoma. Two cases of EST of the vagina in infants aged 9 and 17 months are reported. Both the patients presented with bleeding per vagina and clinically and by ultrasonography were diagnosed as sarcoma botryoides. Both were diagnosed as primary yolk sac tumors. The serum alfa fetoprotein (AFP) level was 4325 and 9328 ng/ml, respectively. One patient aged 9 months expired 2 months after receiving chemotherapy. The other, aged 17 months, was given chemotherapy followed by surgery with reduction of the AFP levels. PMID:19679975

Gangopadhyay, Mimi; Raha, Kalpana; Sinha, Swapan K; De, Anuradha; Bera, Pranati; Pati, Shyamapada

2009-01-01

25

Ultrastructural characteristics of the vaginae of the basal monogenean Chimaericola leptogaster (Leuckart, 1830).  

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In the first study of the vaginal ultrastructure of any monogenean, the paired vaginae of Chimaericola leptogaster, a basal polyopisthocotylean from the gills of a holocephalan, are described. Each vagina opens laterally. A unique feature of this relict parasite is a short vagino-intestinal connecting duct, the lining of which is separated by septate junctions from the linings of the vagina and the intestine. After giving rise to this vagino-intestinal duct, each vagina travels in a posterior direction and opens into the vitelline collecting duct. The lining of each vagina close to the vaginal pore resembles the body tegument, the syncytial lining of which measures about 2.5 ?m in thickness and has a dense surface layer 0.2 ?m in thickness and different apical projections. Proximal to this and before the entrance to the vaginal-intestinal duct, the vaginal lining is characterised by: uniformly distributed electron-dense, lanceolate, spine-like surface structures of about 1.7 ?m in length; three kinds of surrounding glands with three kinds of secretory granules (abundant oval or rounded electron-dense granules 0.7-2.5 ?m in length, much less numerous spheroidal, vesicular granules 0.3-0.4 ?m in diameter, and tightly packed, spheroidal granules 0.8 ?m in diameter and containing fine particulate material of low density); and four kinds of sensory receptors (three uniciliate and one aciliate). These features are absent from the rest of the vagina. The likely roles of the vagino-intestinal connection, the different gland cells, sensory structures, and the armament of the distal vaginal regions are discussed. Considering the suggested polyopisthocotylean ancestor for the Neodermata, the relict parasite fauna of holocephalans and the unique vagino-intestinal connection in C. leptogaster, which is also known in turbellarians, an ancient origin for chimaericolids is supported. PMID:24043615

Poddubnaya, Larisa G; Hemmingsen, Willy; Gibson, David I

2013-12-01

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Committee Opinion No. 571: Solutions for surgical preparation of the vagina.  

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Currently, only povidone-iodine preparations are approved for vaginal surgical-site antisepsis. However, there are compelling reasons to consider chlorhexidine gluconate solutions for off-label use in surgical preparation of the vagina, especially in women with allergies to iodine. Although chlorhexidine gluconate solutions with high concentrations of alcohol are contraindicated for surgical preparation of the vagina, solutions with low concentrations of alcohol (eg, 4%) are both safe and effective for off-label use as vaginal surgical preparations and may be used as an alternative to iodine-based preparations in cases of allergy or when preferred by the surgeon. PMID:23963423

2013-09-01

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Cytological Diagnosis of Small Cell Carcinoma of Vagina - A Diagnostic Dilemma  

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Full Text Available Small cell carcinoma is a neuroendocrine tumour, mainly arises in lung accounting for 20%of cases. In extra pulmonary sites it accounts for 5% of cases. Among gynaecological malignancies it accounts for 1-2% of cases, common sites are cervix, endometrium, ovary, vagina, vulva in decreasing frequencies. Small cell carcinoma is extremely uncommon in vagina.There are only 26 cases reported in the literature. Here we are reporting 27 th case. Because of its rarity the chances of missing the diagnosis are more. Correct morphological identification, with immunohistochemical analysis is essential for definitive diagnosis which will be helpful in planning appropriate treatment.

B. R. Yelikar

2013-01-01

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Melanoma amelanótico primario de vagina: reporte de un caso y revisión de la literatura / Primary amelanotic melanoma of the vagina: a case report and literature review  

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Full Text Available SciELO Colombia | Language: Spanish Abstract in spanish Objetivo: revisar el diagnóstico clínico, histológico e inmunohistoquímico; las alternativas terapéuticas y los factores que influyen en el pronóstico del melanoma amelanocítico de vagina. Materiales y métodos: se presenta el caso de una paciente de 49 años que consultó por masa vaginal de 8 cm en p [...] ared anterior de vagina, nacarada y con fondo necrótico a la Unidad de Patología Cervical y Colposcopia del Hospital de Engativá, institución de segundo nivel de complejidad que atiende pacientes de nivel socioeconómico bajo afiliados al régimen de seguridad pública. Se realizó resección amplia de la lesión. La patología quirúrgica informó melanoma fusocelular y epiteloide maligno. Se realizó una búsqueda sistemática usando las palabras clave: melanoma primario y vagina en las bases de datos Medline vía PubMed, Cochrane y Ebsco. Resultados: se encontraron 489 artículos de los cuales 31 estaban relacionados directamente con el tema, de estos se seleccionaron diez que correspondieron a nueve reportes de caso y a una revisión del tema. El diagnóstico clínico no es fácil. Las proteínas HMB45 y S100 son de gran utilidad en su identificación. La respuesta al tratamiento quirúrgico, la radioterapia y la quimioterapia es pobre. El pronóstico depende de la ploidía, la amelanosis y el índice mitótico. Conclusiones: el melanoma primario de vagina es una neoplasia rara y de mal pronóstico. Hace parte del grupo de melanomas de mucosa que tienen un origen y comportamiento biológico diferente al cutáneo. Tiene tendencia a la diseminación hematógena rápida y a recaídas locales. El tratamiento se basa en cirugía conservadora, radioterapia, quimioterapia y terapia biológica; sin embargo, su eficacia es limitada. Abstract in english Objective: reviewing clinical, histological and immunohistochemical diagnosis, therapeutic alternatives and factors influencing prognosis for amelanotic melanoma of the vagina. Materials and methods: this article presents the case of a 49yearold patient who consulted the Engativá Hospital’s Cervical [...] Pathology and Colposcopy Unit due to an 8 cm diameter necrotic pearlywhite vaginal mass on the anterior vaginal wall. The hospital is a secondary level complexity institution dealing with low socioeconomic level patients affiliated to the public (subsidized) social security (health) system. A broad resection was made of the lesion. Surgical pathology revealed epithelioid fusocellular malignant melanoma. A systematic literature search was made using the following key words: primary melanoma and vagina in Medline databases via Pub Med, Cochrane and Ebsco. Results: 31 of the 489 articles found were directly related to the topic; 10 new case reports and a review were selected. Clinical diagnosis is not easy; HMB45 and S100 proteins are extremely useful in identifying it.Response to surgical treatment, radiotherapy and chemotherapy is poor. Prognosis depends on ploidy, amelanosis and mitotic index. Conclusions: Primary melanoma of the vagina is a rare neoplasm and has a poor prognosis. It forms part of a group of mucosal melanoma having an origin and biological behavior different to that of cutaneous melanoma. It tends to have rapid hematogenous dissemination and local relapses. Treatment is based on conservative surgery, radiotherapy, chemotherapy and biological therapy; however, its effectiveness is limited.

María Paula, Houghton-Martínez; Jairo, Amaya-Guío; Luz Amparo, Díaz-Cruz.

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Melanoma amelanótico primario de vagina: reporte de un caso y revisión de la literatura Primary amelanotic melanoma of the vagina: a case report and literature review  

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Full Text Available Objetivo: revisar el diagnóstico clínico, histológico e inmunohistoquímico; las alternativas terapéuticas y los factores que influyen en el pronóstico del melanoma amelanocítico de vagina. Materiales y métodos: se presenta el caso de una paciente de 49 años que consultó por masa vaginal de 8 cm en pared anterior de vagina, nacarada y con fondo necrótico a la Unidad de Patología Cervical y Colposcopia del Hospital de Engativá, institución de segundo nivel de complejidad que atiende pacientes de nivel socioeconómico bajo afiliados al régimen de seguridad pública. Se realizó resección amplia de la lesión. La patología quirúrgica informó melanoma fusocelular y epiteloide maligno. Se realizó una búsqueda sistemática usando las palabras clave: melanoma primario y vagina en las bases de datos Medline vía PubMed, Cochrane y Ebsco. Resultados: se encontraron 489 artículos de los cuales 31 estaban relacionados directamente con el tema, de estos se seleccionaron diez que correspondieron a nueve reportes de caso y a una revisión del tema. El diagnóstico clínico no es fácil. Las proteínas HMB45 y S100 son de gran utilidad en su identificación. La respuesta al tratamiento quirúrgico, la radioterapia y la quimioterapia es pobre. El pronóstico depende de la ploidía, la amelanosis y el índice mitótico. Conclusiones: el melanoma primario de vagina es una neoplasia rara y de mal pronóstico. Hace parte del grupo de melanomas de mucosa que tienen un origen y comportamiento biológico diferente al cutáneo. Tiene tendencia a la diseminación hematógena rápida y a recaídas locales. El tratamiento se basa en cirugía conservadora, radioterapia, quimioterapia y terapia biológica; sin embargo, su eficacia es limitada.Objective: reviewing clinical, histological and immunohistochemical diagnosis, therapeutic alternatives and factors influencing prognosis for amelanotic melanoma of the vagina. Materials and methods: this article presents the case of a 49yearold patient who consulted the Engativá Hospital’s Cervical Pathology and Colposcopy Unit due to an 8 cm diameter necrotic pearlywhite vaginal mass on the anterior vaginal wall. The hospital is a secondary level complexity institution dealing with low socioeconomic level patients affiliated to the public (subsidized social security (health system. A broad resection was made of the lesion. Surgical pathology revealed epithelioid fusocellular malignant melanoma. A systematic literature search was made using the following key words: primary melanoma and vagina in Medline databases via Pub Med, Cochrane and Ebsco. Results: 31 of the 489 articles found were directly related to the topic; 10 new case reports and a review were selected. Clinical diagnosis is not easy; HMB45 and S100 proteins are extremely useful in identifying it.Response to surgical treatment, radiotherapy and chemotherapy is poor. Prognosis depends on ploidy, amelanosis and mitotic index. Conclusions: Primary melanoma of the vagina is a rare neoplasm and has a poor prognosis. It forms part of a group of mucosal melanoma having an origin and biological behavior different to that of cutaneous melanoma. It tends to have rapid hematogenous dissemination and local relapses. Treatment is based on conservative surgery, radiotherapy, chemotherapy and biological therapy; however, its effectiveness is limited.

María Paula Houghton-Martínez

2012-03-01

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Non-Diethylstilbestrol-Associated Primary Clear Cell Carcinoma of the Vagina: Two Case Reports with Immunohistochemical Studies and Literature Review  

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Primary clear cell adenocarcinomas most commonly involve the genitourinary system, including the vagina. Previously, primary clear cell adenocarcinomas of the vagina have been discussed within the context of prenatal exposure to diethylstilbestrol. Due to its widely proven role in the development of this carcinoma, administration of diethylstilbestrol is prohibited. We present two cases of non-diethylstilbestrol-associated primary clear cell adenocarcinoma of the vagina from the archives of the Anatomical Pathology Department at King Abdulaziz University in order to improve our understanding of its biological behavior. Our findings suggest that primary clear cell adenocarcinoma of the vagina may be unrelated to diethylstilbestrol exposure and that non-diethylstilbestrol-associated primary clear cell adenocarcinoma of the vagina, when present at a younger age, may have a worse prognosis. PMID:24850989

Mufti, Shagufta T.; Ali, Hiba Hassan

2014-01-01

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Mioepitelioma de vagina: neoplasia poco frecuente en esta localización, reporte de un caso  

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Full Text Available SciELO Chile | Language: Spanish Abstract in spanish Antecedentes: Los mioepiteliomas, son tumores poco frecuentes originados a partir de la proliferación de células mioepiteliales. La mayor parte localizados en las extremidades inferiores y en glándulas salivales. Existen ocasionales informes previos de MEP que involucren la vagina. Objetivo: Describ [...] ir un caso de mioepitelioma localizado en vagina. Caso clínico: Embarazada de 29 años edad, quien presenta una masa vaginal de un año de evolución, localizada en el himen. El examen histopatológico muestra una lesión compuesta por células fusiformes con positividad inmunohistoquímica para vimentina, citoqueratinas (CK) AE1/ AE3, S100, CD10, receptores de estrógenos y progesterona, Bcl2 y calponina y negatividad para desmina, actina muscular especifica, actina de músculo liso y p63. Con los anteriores hallazgos se interpreta la lesión como un mioepitelioma primario vaginal. Conclusión: Los mioepiteliomas son tumores que requieren para su diagnostico, análisis con técnicas de inmunohistoquímica o ultraestructurales que permitan diferenciarlos de otros tumores. Abstract in english Background: The myoepitheliomas are rare tumors arising from the proliferation of myoepithelial cells. Most tumors are located in the lower extremity and salivary glands. There have been only occasional myoepithelial neoplasms previously reported involving the vagina. Objective: Describe a case of m [...] yoepithelioma located in the vagina of a pregnant woman. Case report: A 29 years old pregnant female, who about 1 year prior has a vaginal mass, located in the hymen. At histopathological examination shows a mass composed of spindle cells with positivity immunohistochemical studies for vimentin, cytokeratin AE1/AE3, S100, CD10 and calponin and negative for desmin, actinmuscle specific (HHF35), smooth muscle actin and p63. With these findings it was established the diagnosis of myoepithelioma in the vagina. Conclusion: Myoepitheliomas are tumors requiring for diagnostic of immunohistochemistry or ultrastructural techniques that allow its differentiation from other tumors.

Alfredo, Romero R; Mario, Melo U; Paula, Barajas S; Juvenal, Baena A; Luz Mery, Vargas L.

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Mioepitelioma de vagina: neoplasia poco frecuente en esta localización, reporte de un caso  

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Full Text Available Antecedentes: Los mioepiteliomas, son tumores poco frecuentes originados a partir de la proliferación de células mioepiteliales. La mayor parte localizados en las extremidades inferiores y en glándulas salivales. Existen ocasionales informes previos de MEP que involucren la vagina. Objetivo: Describir un caso de mioepitelioma localizado en vagina. Caso clínico: Embarazada de 29 años edad, quien presenta una masa vaginal de un año de evolución, localizada en el himen. El examen histopatológico muestra una lesión compuesta por células fusiformes con positividad inmunohistoquímica para vimentina, citoqueratinas (CK AE1/ AE3, S100, CD10, receptores de estrógenos y progesterona, Bcl2 y calponina y negatividad para desmina, actina muscular especifica, actina de músculo liso y p63. Con los anteriores hallazgos se interpreta la lesión como un mioepitelioma primario vaginal. Conclusión: Los mioepiteliomas son tumores que requieren para su diagnostico, análisis con técnicas de inmunohistoquímica o ultraestructurales que permitan diferenciarlos de otros tumores.Background: The myoepitheliomas are rare tumors arising from the proliferation of myoepithelial cells. Most tumors are located in the lower extremity and salivary glands. There have been only occasional myoepithelial neoplasms previously reported involving the vagina. Objective: Describe a case of myoepithelioma located in the vagina of a pregnant woman. Case report: A 29 years old pregnant female, who about 1 year prior has a vaginal mass, located in the hymen. At histopathological examination shows a mass composed of spindle cells with positivity immunohistochemical studies for vimentin, cytokeratin AE1/AE3, S100, CD10 and calponin and negative for desmin, actinmuscle specific (HHF35, smooth muscle actin and p63. With these findings it was established the diagnosis of myoepithelioma in the vagina. Conclusion: Myoepitheliomas are tumors requiring for diagnostic of immunohistochemistry or ultrastructural techniques that allow its differentiation from other tumors.

Alfredo Romero R

2012-01-01

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A simple, inexpensive applicator for irradiation of localized areas of the vagina with intracavitary brachytherapy  

International Nuclear Information System (INIS)

Purpose: To describe the construction of a simple, inexpensive applicator for irradiation of localized areas of the vagina with intracavitary brachytherapy Methods and Materials: It was desirable to avoid an interstitial implant in an elderly patient with a stage T2 vaginal cancer. The final phase of radiation therapy was delivered with a custom made intracavitary cylinder that allowed the high-dose area to be limited to the portion of the vagina at high risk for residual disease. The applicator was fabricated from a clear cast acrylic (Lucite) rod with dimensions 3.5 cm diameter x 5.0 cm long. The applicator contained 11 parallel grooves, each 1.8 mm deep x 2.2 mm wide, machined along the surface of the cylinder parallel its long axis at 1.0 cm increments. Plastic needles (15 gauge) were inserted into the grooves along the surface of the acrylic cylinder and held in place with heat shrink tubing. The applicator was easily inserted and positioned without anesthesia. Standard low dose rate 192Ir ribbons were inserted into the plastic needles after positioning the applicator in the vagina. Results: Construction of this applicator system requires a few weeks notice and approximately $150. Fabrication of the grooved cylinder is a routine task for a workshop with a milling machine. A step-by-step description of how to construct and use the applicator is provided along with the telephone numbers of commercial vendors to call to order all necessary materials. Concall to order all necessary materials. Conclusion: This article describes a simple, inexpensive method for constructing a customized vaginal applicator that can be used to treat a limited area of the vagina with intracavitary brachytherapy

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Verrucous carcinoma of the cervix and vagina treated by radiation therapy  

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Seven cases of verrocous carcinoma of the uterine cervix (five) and vagina (two) were reviewed. Four of the five patients managed primarily with radiation therapy have survived a median of 10 years. Of the two patients managed primarily with surgery, one experienced recurrence and was then successfully treated with radiation therapy; the other died of metastatic carcinoma. No anaplastic transformation of lesions or distant metastases occurred in the patients treated with radiation therapy. Human papilloma virus was isolated in two patients

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Measuring the space between vagina and rectum as it relates to rectocele  

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Full Text Available AIM: To measure the normal space between the posterior wall of the vagina and the anterior wall of the respectively rectum using computed tomography (CT and reveal its were relationship to rectocele.METHODS: A total of twenty female volunteers without rectocele were examined by CT scan. We performed a middle level continuous horizontal pelvic scan from the upper part to the lower part and collected the measurement data to analyze the results using t-test.RESULTS: Twenty volunteers were enrolled in the study. The space between the posterior wall of the vagina and the anterior wall of the rectum was measured at three levels (upper 1/3, middle, lower 1/3 level of vagina. The results showed that the space from the posterior wall of the vagina to the anterior wall of the rectum at the upper 1/3 level and the middle level was 3.896 ± 0.3617 mm and 4.6575 ± 0.3052 mm, respectively. When the two groups of data were compared, we found the space at the upper 1/3 level was shorter than at the middle level (P < 0.01. Moreover, at the lower 1/3 level the space measured was 10.058 ± 0.4534 mm. The results revealed that the space at the lower 1/3 level was longer than that at the middle level (P < 0.01.CONCLUSION: These measurement data may be helpful in assessing rectocele clinical diagnosis and functional outcomes of rectocele repair.

Jin Liu, Li-Dong Zhai, Yun-Sheng Li, Wan-Xiang Liu, Rui-Hua Wang

2009-06-01

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CT and MR imaging findings of primary leiomyosarcoma of the vagina : a case report  

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Primary malignant lesions of the vagina are uncommon and represent approximately 1-2% of all gynecologic malignancies. About 2% of all malignant vaginal lesions are primary sarcomas, the most common of these being leiomyosarcoma. We report the CT and MR imaging findings in a 41-year-old woman with vaginal leiomyosarcoma presenting as a bulky solid mass which caused expansion of the vaginal canal

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Compensatory structural adaptive modifications of vagina in response to functional demand in goat.  

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Vaginal biopsies and smears were collected from ten adult local healthy goats. Routine histological methods were carried out on vaginal biopsies and then stained with PAS stain. The smears were stained with Methylene blue. All samples were inspected under light microscope. The present study found that many constituents of the wall of the vagina, which have an important functional role, were absent; among these were the vaginal glands, goblet cells, muscularis mucosa, and lymphatic nodules. On the other hand, vagina showed special compensatory histological mechanisms, namely, the deep epithelial folds, the well-developed germinated stratum basale, the apparent basement membrane, and the profuse defensive cells, such as neutrophils, macrophages, lymphocytes, plasma cells, and mast cells. The general stains of this study could not recognize dendritic cells although they play an important functional role. Moreover, the herein study declared also that the vaginal smears showing many adaptive cellular mechanisms among these were, the keratinization, the process of sheet formation that lines the vaginal lumen, the process of metachromasia which is related to the cellular activity in protein synthesis, keratin, and finally the presence of endogenous microorganisms. It was concluded that all the above cellular compensatory adaptive mechanisms may compensate the lacking vaginal constituents and act to raise the immune response of the vagina. PMID:24707438

Hussin, Amer M; Zaid, Nazih W; Hussain, S O

2014-01-01

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Fine structure of the male reproductive ducts, vagina and seminal receptacle of Cyathocephalus truncatus (Cestoda: Spathebothriidea).  

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Fine structure of the vas efferens, vas deferens, ejaculatory duct with accessory glands and vagina with seminal receptacle is described in the spathebothriidean tapeworm, Cyathocephalus truncatus (Pallas, 1781) Kessler, 1868. The numerous well-developed prostate glands are characterised by having secretory granules with an electron-dense core surrounded by a matrix of lower electron density. Coalescence of the outer part of the granules with each other takes place in the terminal end of the secretory ducts. The position of prostate glands around the proximal part of the cirrus pouch and terminating in the ejaculatory duct is a characteristic feature of the Spathebothriidea. Up to 20 closely arranged muscle layers make up the muscular cirrus pouch wall with 4 well-developed muscular layers in the ejaculatory duct and cirrus. Both the cirrus and the vagina are covered with the same uniform cone-shaped microtriches. The vagina has an extensive seminal receptacle. All of these structures are well-adapted to insure successful sperm transfer involving ejaculation and storage, probably for both self- and cross-insemination. Cyathocephalus truncatus has a cirrus similar to that of the monozoic, progenetic caryophyllidean, Archigetes sieboldi and well-developed prostate glands like those of the polyzoic pseudophyllidean, Diphyllobothrium latum. The ultrastructural aspects of the male and female reproductive system of C. truncatus are compared with those of other tapeworms. PMID:16270805

Poddubnaya, Larisa G; Mackiewicz, John S; Brunanská, Magdaléna; Dezfuli, Bahram S

2005-09-01

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Definitive radiation therapy for invasive carcinoma of the vagina. Impact of high-dose rate intracavitary brachytherapy  

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ge in one, grade 3 cystitis in one, and grade 4 cystitis in one. Our results demonstrated that definitive RT with HDR-ICBT is effective for invasive carcinoma of the vagina, with acceptable toxicity. (author)

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Association of Atopobium vaginae, a recently described metronidazole resistant anaerobe, with bacterial vaginosis  

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Full Text Available Abstract Background Bacterial vaginosis (BV is a polymicrobial syndrome characterized by a change in vaginal flora away from predominantly Lactobacillus species. The cause of BV is unknown, but the condition has been implicated in diverse medical outcomes. The bacterium Atopobium vaginae has been recognized only recently. It is not readily identified by commercial diagnostic kits. Its clinical significance is unknown but it has recently been isolated from a tuboovarian abcess. Methods Nucleotide sequencing of PCR amplified 16S rRNA gene segments, that were separated into bands within lanes on polyacrylamide gels by denaturing gradient gel electrophoresis (DGGE, was used to examine bacterial vaginal flora in 46 patients clinically described as having normal (Lactobacillus spp. predominant; Nugent score ? 3 and abnormal flora (Nugent score ? 4. These women ranged in age from 14 to 48 and 82% were African American. Results The DGGE banding patterns of normal and BV-positive patients were recognizably distinct. Those of normal patients contained 1 to 4 bands that were focused in the centre region of the gel lane, while those of BV positive patients contained bands that were not all focused in the center region of the gel lane. More detailed analysis of patterns revealed that bands identified as Atopobium vaginae were present in a majority (12/22 of BV positive patients, while corresponding bands were rare (2/24 in normal patients. (P A. vaginae isolates were cultivated from two patients whose DGGE analyses indicated the presence of this organism. Two A. vaginae 16S rRNA gene sequences were identified among the clinical isolates. The same two sequences were obtained from DGGE bands of the corresponding vaginal flora. The sequences differed by one nucleotide over the short (~300 bp segment used for DGGE analysis and migrated to slightly different points in denaturing gradient gels. Both isolates were strict anaerobes and highly metronidazole resistant. Conclusion The results suggest that A. vaginae may be an important component of the complex bacterial ecology that constitutes abnormal vaginal flora. This organism could play a role in treatment failure if further studies confirm it is consistently metronidozole resistant.

Fortenberry J Dennis

2004-02-01

 
 
 
 
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Pre leukemic granulocytic sarcoma of vagina: a case report with review of literature  

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Granulocytic sarcoma is an extramedullary tumor of malignant granulocytic progenitor cells, that may precede the onset of acute myeloid leukemia or appear during the leukemic manifestation or blastic crisis of chronic myeloproliferative disorders. A case of granulocytic sarcoma of vagina in a 27 year old woman treated with local radiotherapy is described. After seven months of follow up she developed acute myeloid leukemia. The case has been presented in view of its rarity and discussed in light of the available literature. (author). 13 refs., 1 fig

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Sperm-storage tubules in the vagina of the ostrich (Struthio camelus)  

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Sperm-storage tubules have been described in a number of species of birds. The presence of these tubules in the Rhea has been mentioned, but no description of these structures in ratites is available. The purpose of this study was to determine the presence and morphology of sperm-storage tubules in the vagina of the ostrich. The study was performed with the use of conventional light- and electron-microscopic techniques. Sperm-storage tubules were located in a 200-mm-wide band of t...

Bezuidenhout, A. J.; Soley, John Thomson; Groenewald, Hermanus B.; Burger, W. P.

1995-01-01

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Melanosis of the vagina and human papillomavirus infection, an uncommon pathology: Case Report / Melanosis de la vagina e infección por virus del papiloma humano, una patología poco común: Reporte de un Caso  

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Full Text Available SciELO Venezuela | Language: English Abstract in spanish Las lesiones melanóticas de la vagina son infrecuentes. y Solo pocos casos han sido reportados. Se presenta el caso de una mujer de 34 años quien es referida con diagnóstico de una Neoplasia Intraepitelial Vaginal 1. Al examen ginecológico, se encontraron dos áreas hiperpigmentadas en la vagina. La [...] exploración colposcópica del cuello uterino y vagina reveló la presencia de una lesión aceto-blanca en la pared lateral derecha del tercio superior de la vagina. Muestras de biopsias fueron tomadas en dichas áreas. El estudio histológico reportó una melanosis de la vagina y una infección por el virus del Papiloma Humano (VPH). Se realizó un panel de estudio inmunohistoquímico de marcadores epiteliales en las muestras vaginales: tales como citoqueratina AE1/AE3 y antígeno epitelial de membrana; marcador mesenquimal: vimentin; marcadores melanóticos: proteina S-100 y HMB45 (Human Melanoma Black); marcadores de proliferación celular: antígeno de proliferación nuclear (PCNA), y la oncoproteína P-53. Se realizó Hibridización In Situ para establecer los tipos de alto (16, 18, 31, 45) y bajo (6, 11) riesgo de VPH en las muestras vaginales. Los marcadores CK, EMA y Vimentin fueron 2+. Los marcadores melanótico, el HMB45 y el S100, y el PCNA fueron 1+ en la capa basal. P-53 fue negativo. El tejido melanótico y la lesión acetoblanca fueron positivos al VPH 6,11. En conclusión, la melanosis vaginal es una patología poco frecuente. Usualmente, se ha reportado en mujeres mayores de 40 años. Presentamos un caso de una melanosis de la vagina infectada con un tipo de VPH de bajo riesgo en una mujer joven y una revisión de la literatura. Abstract in english Benign melanotic lesions of the vagina are uncommon and only a few cases have been reported in the literature. A 34-year-old woman was referred because of a Vaginal Intraepithelial Neoplasia 1 biopsy result. On the gynecological examination, two different hyperpigmented areas were noted in the vagin [...] a. The colposcopic visualization of the cervix and vagina found an aceto-white lesion at the right lateral wall of the upper third of the vagina. Biopsies from three areas were taken. Histological study reported a melanosis of the vagina and HPV infection. An immunohistochemical panel of epithelial markers was performed in vaginal samples, such as Cytokeratin AE1/AE3 and epithelial membrane antigen, mesenchymal marker: vimentin; melanocytic makers: protein S-100 and HMB45 (Human Melanoma Black); proliferating cell marker: proliferating cell nuclear antigen (PCNA), and P-53 oncoprotein. High Risk (16, 18, 31, 45) and Low Risk (6, 11) HPV types were studied by In Situ Hybridization using the same vaginal samples. CK, EMA and Vimentin were 2+. Melanocytic markers, HMB45 and S100, and PCNA were 1+ in basal cell layer. P-53 was negative. The melanotic tissue and acetowhite lesion were positives to HPV Types 6,11. In conclusion, melanosis of the vagina is a uncommon benign pathology. Usually, melanosis is present in women over 40 years old. We present a case of melanosis of the vagina in a young woman infected with low-risk HPV types and review the literature.

José, Núñez-Troconis; Mariela, Delgado; Gerardo, González; Airiaudis, Rivas; Katherine, Molero.

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Melanosis of the vagina and human papillomavirus infection, an uncommon pathology: Case Report / Melanosis de la vagina e infección por virus del papiloma humano, una patología poco común: Reporte de un Caso  

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Full Text Available SciELO Venezuela | Language: English Abstract in spanish Las lesiones melanóticas de la vagina son infrecuentes. y Solo pocos casos han sido reportados. Se presenta el caso de una mujer de 34 años quien es referida con diagnóstico de una Neoplasia Intraepitelial Vaginal 1. Al examen ginecológico, se encontraron dos áreas hiperpigmentadas en la vagina. La [...] exploración colposcópica del cuello uterino y vagina reveló la presencia de una lesión aceto-blanca en la pared lateral derecha del tercio superior de la vagina. Muestras de biopsias fueron tomadas en dichas áreas. El estudio histológico reportó una melanosis de la vagina y una infección por el virus del Papiloma Humano (VPH). Se realizó un panel de estudio inmunohistoquímico de marcadores epiteliales en las muestras vaginales: tales como citoqueratina AE1/AE3 y antígeno epitelial de membrana; marcador mesenquimal: vimentin; marcadores melanóticos: proteina S-100 y HMB45 (Human Melanoma Black); marcadores de proliferación celular: antígeno de proliferación nuclear (PCNA), y la oncoproteína P-53. Se realizó Hibridización In Situ para establecer los tipos de alto (16, 18, 31, 45) y bajo (6, 11) riesgo de VPH en las muestras vaginales. Los marcadores CK, EMA y Vimentin fueron 2+. Los marcadores melanótico, el HMB45 y el S100, y el PCNA fueron 1+ en la capa basal. P-53 fue negativo. El tejido melanótico y la lesión acetoblanca fueron positivos al VPH 6,11. En conclusión, la melanosis vaginal es una patología poco frecuente. Usualmente, se ha reportado en mujeres mayores de 40 años. Presentamos un caso de una melanosis de la vagina infectada con un tipo de VPH de bajo riesgo en una mujer joven y una revisión de la literatura. Abstract in english Benign melanotic lesions of the vagina are uncommon and only a few cases have been reported in the literature. A 34-year-old woman was referred because of a Vaginal Intraepithelial Neoplasia 1 biopsy result. On the gynecological examination, two different hyperpigmented areas were noted in the vagin [...] a. The colposcopic visualization of the cervix and vagina found an aceto-white lesion at the right lateral wall of the upper third of the vagina. Biopsies from three areas were taken. Histological study reported a melanosis of the vagina and HPV infection. An immunohistochemical panel of epithelial markers was performed in vaginal samples, such as Cytokeratin AE1/AE3 and epithelial membrane antigen, mesenchymal marker: vimentin; melanocytic makers: protein S-100 and HMB45 (Human Melanoma Black); proliferating cell marker: proliferating cell nuclear antigen (PCNA), and P-53 oncoprotein. High Risk (16, 18, 31, 45) and Low Risk (6, 11) HPV types were studied by In Situ Hybridization using the same vaginal samples. CK, EMA and Vimentin were 2+. Melanocytic markers, HMB45 and S100, and PCNA were 1+ in basal cell layer. P-53 was negative. The melanotic tissue and acetowhite lesion were positives to HPV Types 6,11. In conclusion, melanosis of the vagina is a uncommon benign pathology. Usually, melanosis is present in women over 40 years old. We present a case of melanosis of the vagina in a young woman infected with low-risk HPV types and review the literature.

José, Núñez-Troconis; Mariela, Delgado; Gerardo, González; Airiaudis, Rivas; Katherine, Molero.

2011-09-01

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Peculiar tonsil-like structure near vagina of the laboratory shrew, Suncus murinus.  

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After finding tonsil-like structures near the entrance of vagina of a laboratory shrew (Suncus murinus), which we subsequently designated as vaginal tonsils, we performed detailed immunohistochemical and developmental studies. The location of T and B cells in the vaginal tonsils differed from that in the palatine tonsils or that in the lymphoid nodes of other animals. The boundary between the germinal center region and the region encompassing follicular interfollicular tissue was not clear. B cells were widely distributed and very dense in the parenchyma, but they were scattered in the epithelial area (B cells were present in around 90% of the vaginal tonsil tissue). In contrast, T cells were scattered in the parenchyma and in the epithelial area (T cells were present in around 10% of the vaginal tonsil tissue). B cells were more prominent than T cells throughout the development of these structures and the epithelium was invaded by many immigrating cells. The size of the vaginal tonsils changed during postnatal development. Vaginal tonsils are structurally similar to other tonsils, and they may function to protect the vagina from infection. PMID:23614982

Sakai, Kazuyoshi; Imada, Hideki; Shinzato, Masanori; Nishii, Kazuhiro; Miyachi, Ei-ichi; Katoh, Yoshimitsu; Yamada, Kouji

2013-01-01

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Morphology, morphometry, histochemistry and lectin histochemistry of the vagina of the plains viscacha (Lagostomus maximus).  

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The aim of the present work was to describe the morphology of the vagina in Lagostomus maximus and to characterize its epithelial cells using morphometric and histochemical techniques (variations of PAS, Alcian blue and lectin histochemistry). Thirty-five sexually mature adult females were captured in their natural environment during four periods of the year and their genital organs were dissected. The vaginal wall of the viscacha has three tunics: mucosa, muscularis and adventitia or serosa according to the region. The epithelium is stratified in both cranial and caudal regions, but its characteristics vary depending on the physiological state. In anestrous, nonpregnant females have a stratified epithelium of two to three cellular layers with columnar PAS-positive superficial mucous cells. During the follicular phase, the epithelium of the vagina is stratified squamous and cornified. Females at early, middle and term pregnancy have a columnar stratified epithelium with mucous cells. Glycoproteins in the mucous cells were detected using PAS, PA*S, KOH/PA*/BH/PAS; and Alcian blue, pH 0.5, pH 1, pH 2.5 and 0.006 M). Lectin histochemistry showed that UEA-I and RCA-1 lectins reacted strongly or moderately with epithelial cells in all stages analyzed. These results indicate the presence of L-fucose and ?-galactose. Binding with other lectins was variable. PMID:21351822

Flamini, M A; Díaz, A O; Barbeito, C G; Portiansky, E L

2012-02-01

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Primary invasive carcinoma of the vagina after Le Fort partial colpocleisis for stage IV pelvic organ prolapse: a case report.  

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We present here the case report of a postmenopausal woman who complained of recurrent pus-like vaginal discharge and perianal pain 1 year after Le Fort colpocleisis, which was subsequently identified as a primary invasive carcinoma of the vagina. Biopsy confirmed a squamous cell carcinoma in the vagina, and the disease was classified as stage III according to FIGO staging. The patient received pelvic radiotherapy. This case emphasizes that differential diagnosis of recurrent vaginal discharge that presents remote from obliterative procedure for pelvic organ prolapse should consider not only pyometra, but also other causes. PMID:21562914

Cho, Moon Kyoung; Kim, Chul Hong; Kim, Yoon Ha

2011-11-01

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A case of rhabdomyosarcoma of the vagina in an elderly woman.  

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Most rhabdomyosarcomas of the vagina (RMSV) occur in infants and children up to six years old. RMSV in elderly patients is extremely rare. We report a case of a 70-year-old woman with RMSV. She had received surgery for uterine endometrial cancer one year before and a vaginal polypoid tumor was noted during routine follow-up vaginal examination. She was referred to our department for radiation therapy following partial tumorectomy of the lesion. She was given three sessions of intra-vaginal radiation therapy, once a week with 6 Gy at 7.5 mm below the vaginal surface and external irradiation of 50 Gy to the pelvis. However, paraaortal lymph node metastasis developed during initial radiation therapy. Furthermore, multiple bone metastases appeared at the completion of the radiation therapy. Six months after initial treatment the patient died from progression of the disease. Autopsy demonstrated small residual tumor at the primary site as well as multiple systemic metastases. PMID:15285317

Suzuki, Y; Sakurai, H; Hasegawa, M; Kanuma, T; Segawa, A; Nakano, T

2004-01-01

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Microbiological analysis of the uterus and vagina of nulliparous and non-nulliparous agoutis (Dasyprocta azarae  

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Full Text Available The genital organs of domestic animals are usually colonized by several microorganisms. This paper aims at describing the uterine and vaginal microbiota of nulliparous and non-nulliparous agoutis, which belong to the Catanduva City Zoo, Sao Paulo, Brazil. During the procedure of ovariosalpingohisterectomy, material was collected for microbiological analysis through the introduction of sterile swabs in the vagina and in each uterine horn. The presence of Proteus sp. was observed in the uterine material of only one animal. In the vaginal material of all animals, several bacteriae (Proteus sp., Escherichia coli, Citrobacter sp., Pseudomonas sp., and Staphylococcus sp. and yeasts were found. The vaginal and uterine microbiota of agoutis presents a colonization pattern different from that observed in other domestic animals, in women, and in female rats.

Leandro Luis Martins

2012-11-01

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The oophorectomy effect on Walker 256 tumor inoculated into the vagina and uterine cervix of female rats Efeito da ooforectomia no tumor de Walker 256 inoculado em vagina e colo de útero de ratos fêmeas  

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Full Text Available PURPOSE: Verify the effect of oophorectomy on the evolution of the Walker 256 tumor inoculated into the vagina and cervix of female rats. METHODS: Ten Wistar, female rats were used, distributed into two groups with 05 animals each: Tumor group (TG: Rats inoculated with Walker 256 tumor; Oophorectomy group (OG: oophorectomized rats inoculated with Walker 256 tumor. The day before the tumor vaginal inoculation, acetic acid was inoculated into the vaginas of both groups of rats; the following day, the vaginal walls were scarified with an endocervix brush, and then Walker 256 tumor was inoculated. After 12 days, the tumor was removed together with the vagina and uterine horns for macro and microscopic analyses. The data were submitted to statistical analyses. RESULTS: There was no statistical difference between the two groups; however it was observed that the behavior of tumor growth on the OG group presented greater invasion, compromising the uterine horns. CONCLUSION: The results of the study on the GO group presented a macroscopic behavior different from the TG group, however, both of them presented similar development in terms of tumor mass.OBJETIVO: Verificar o efeito da ooforectomia à inoculação do tumor de Walker 256 em vagina e colo de útero de ratas. MÉTODOS: Foram utilizadas 10 ratas Wistar, fêmeas, virgens, adultas, distribuídas em dois grupos de estudo com 05 animais cada: grupo tumor (GT: ratas inoculadas com tumor de Walker 256, e grupo Ooforectomia (GO: ratas ooforectomizadas e inoculadas com tumor de Walker 256. No dia anterior à inoculação vaginal do tumor, foram inoculados 0,3ml de ácido acético na vagina das ratas de ambos os grupos; no dia seguinte, foi realizada a escarificação da parede vaginal com uma escova de endocérvice e inoculado tumor de Walker 256. Após 12 dias, foi removido o tumor em bloco com vagina e cornos uterinos para análise macro e microscópica. Os dados foram submetidos à análise estatística. RESULTADOS: Não houve diferença estatística entre os dois grupos; no entanto, notou-se que o comportamento de crescimento do tumor no grupo GO apresentou maior invasividade em extensão, comprometendo cornos uterinos. CONCLUSÃO: Observou-se que o grupo GO apresentou comportamento macroscópico diferente ao grupo GT, no entanto, em termos totais de massa tumoral ambos apresentam desenvolvimento similar.

Nara Macedo Botelho Brito

2009-02-01

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The oophorectomy effect on Walker 256 tumor inoculated into the vagina and uterine cervix of female rats / Efeito da ooforectomia no tumor de Walker 256 inoculado em vagina e colo de útero de ratos fêmeas  

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Full Text Available SciELO Brazil | Language: English Abstract in portuguese OBJETIVO: Verificar o efeito da ooforectomia à inoculação do tumor de Walker 256 em vagina e colo de útero de ratas. MÉTODOS: Foram utilizadas 10 ratas Wistar, fêmeas, virgens, adultas, distribuídas em dois grupos de estudo com 05 animais cada: grupo tumor (GT): ratas inoculadas com tumor de Walker [...] 256, e grupo Ooforectomia (GO): ratas ooforectomizadas e inoculadas com tumor de Walker 256. No dia anterior à inoculação vaginal do tumor, foram inoculados 0,3ml de ácido acético na vagina das ratas de ambos os grupos; no dia seguinte, foi realizada a escarificação da parede vaginal com uma escova de endocérvice e inoculado tumor de Walker 256. Após 12 dias, foi removido o tumor em bloco com vagina e cornos uterinos para análise macro e microscópica. Os dados foram submetidos à análise estatística. RESULTADOS: Não houve diferença estatística entre os dois grupos; no entanto, notou-se que o comportamento de crescimento do tumor no grupo GO apresentou maior invasividade em extensão, comprometendo cornos uterinos. CONCLUSÃO: Observou-se que o grupo GO apresentou comportamento macroscópico diferente ao grupo GT, no entanto, em termos totais de massa tumoral ambos apresentam desenvolvimento similar. Abstract in english PURPOSE: Verify the effect of oophorectomy on the evolution of the Walker 256 tumor inoculated into the vagina and cervix of female rats. METHODS: Ten Wistar, female rats were used, distributed into two groups with 05 animals each: Tumor group (TG): Rats inoculated with Walker 256 tumor; Oophorectom [...] y group (OG): oophorectomized rats inoculated with Walker 256 tumor. The day before the tumor vaginal inoculation, acetic acid was inoculated into the vaginas of both groups of rats; the following day, the vaginal walls were scarified with an endocervix brush, and then Walker 256 tumor was inoculated. After 12 days, the tumor was removed together with the vagina and uterine horns for macro and microscopic analyses. The data were submitted to statistical analyses. RESULTS: There was no statistical difference between the two groups; however it was observed that the behavior of tumor growth on the OG group presented greater invasion, compromising the uterine horns. CONCLUSION: The results of the study on the GO group presented a macroscopic behavior different from the TG group, however, both of them presented similar development in terms of tumor mass.

Nara Macedo Botelho, Brito; Rita de Kássia Vidigal, Carvalho; Lia Tavares de Moura Brasil, Matos; Rodolfo Costa, Lobato; Rosângela Baía, Brito.

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Factors affecting long-term outcome of irradiation in carcinoma of the vagina  

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Objective: This report evaluates prognostic and technical factors affecting outcome of patients with primary carcinoma of the vagina treated with definitive radiation therapy. Methods and Materials: A retrospective analysis was performed on records of 212 patients with histologically confirmed carcinoma of the vagina treated with irradiation. Results: Tumor stage was the most significant prognostic factor; actuarial 10-year disease-free survival was 94% for Stage 0 (20 patients), 80% for Stage I (59 patients), 55% for Stage IIA (63 patients), 35% for Stage IIB (34 patients), 38% for Stage III (20 patients), and 0% for Stage IV (15 patients). All in situ lesions except one were controlled with intracavitary therapy. Of the patients with Stage I disease, 86% showed no evidence of vaginal or pelvic recurrence; most of them received interstitial or intracavitary therapy or both, and the addition of external-beam irradiation did not significantly increase survival or tumor control. In Stage IIA (paravaginal extension) and IIB (parametrial involvement) 66% and 56% of the tumors, respectively, were controlled with a combination of brachytherapy and external-beam irradiation; 13 of 20 (65%) Stage III tumors were controlled in the pelvis. Four patients with Stage IV disease (27%) had no recurrence in the pelvis. The total incidence of distant metastases was 13% in Stage I, 30% in Stage IIA, 52% in Stage IIB, 50% in Stage III, and 47% in Stage IV. The dose of irradiation deliven Stage IV. The dose of irradiation delivered to the primary tumor or the parametrial extension was of relative importance in achieving successful results. In patients with Stage I disease, brachytherapy alone achieved the same local tumor control (80-100%) as in patients receiving external pelvic irradiation (78-100%) as well. In Stage II and III there was a trend toward better tumor control (57-80%) with combined external irradiation and brachytherapy than with the latter alone (33-50%) (p = 0.42). The incidence of grade 2-3 complications (12%) correlated with the stage of the tumor and type of treatment given. Conclusion: Radiation therapy is an effective treatment for patients with vaginal carcinoma, particularly Stage I. More effective irradiation techniques, including optimization of dose distribution combining external irradiation and interstitial brachytherapy in tumors beyond Stage I, are necessary to enhance locoregional tumor control. The high incidence of distant metastases emphasizes the need for earlier diagnosis and effective systemic cytotoxic agents to improve survival in these patients

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Experimental inoculation model of Walker 256 carcinoma into vagina and cervix uteri of female rats Modelo experimental de Tumor de Walker 256 em vagina e colo de útero de ratas  

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Full Text Available PURPOSE: To establish an inoculation model of Walker 256 carcinoma on cervix uteri and vagina of rats. METHODS: Fifteen female rats were used, and assigned to three groups each one with five rats: group A - rats with 4x10(6 cells of Walker 256 carcinoma without acid acetic inoculation; group B - rats with 2x10(6 cells of Walker 256 carcinoma with acid acetic inoculation and group C: rats with 4x10(6 cells of Walker 256 carcinoma with acid acetic inoculation. The day before tumor cells inoculation the rats from groups B and C were anaesthetized with diethylether and 0,3 ml of acetic acid was inoculated into their vaginas. Tumor cell inoculation into the vagina and cervix was done under general anesthesia with diethylether. Then a endocervical brush was used to scrape the vaginal wall and after that 0,3 ml of the liquid containing tumor cells was inoculated on the vagina and cervix. For the tumor analysis, animals were euthanized at day 12 following tumor cell implantation by an excessive inhalation of diethylether. Tumor was resected entirely and weighed and the tumors were then sectioned and counter stained with hematoxylin and eosin for histopathologic evaluation. It was also calculated the percentage of tumor equivalent to the body weight by the formula: P= tumor weight / body weight x 100. Data were analyzed by one-way analysis of variance - ANOVA. P values OBJETIVO: Estabelecer um modelo de inoculação de Tumor de Walker 256 em vagina e colo de útero de ratas. MÉTODOS: Foram utilizadas 15 ratas fêmeas, virgens, adultas, pesando entre 200-250g, distribuídas em três grupos de estudo com cinco animais cada: grupo A (GA: ratas com tumor de Walker 256 em concentração de 4x10(6 sem ácido acético; grupo B (GB: ratas com tumor de Walker 256 em concentração de 2x10(6 células com ácido acético; grupo C (GC: ratas com tumor de Walker 256 em concentração de 4x10(6 células com ácido acético. No dia anterior à inoculação do tumor, foi realizada a inoculação de 0,3 ml de ácido acético a 10% na vagina das ratas de GB e GC; no dia seguinte, tanto estas como as ratas do grupo GA foram anestesiadas, feita a escarificação da parede vaginal com uma escova de endocérvice e inoculado 0,3ml de tumor na concentração de 4x10(6 células nos grupos GA e GC e 2x10(6 células no grupo GB. Após 12 dias, foi realizada a eutanásia e removido o tumor em bloco com vagina e cornos uterinos para análise, sendo pesado e averiguado seu volume e calculado as relações entre o seu peso e o peso final da rata e o seu volume e o peso final da rata. Os dados foram colhidos e submetidos à análise estatística pelo método ANOVA (um critério. RESULTADOS: A pega em GB e GC foi 100% e em GA 20%. Não houve diferença estatística entre as médias obtidas entre GB e GC. CONCLUSÃO: De acordo com a metodologia utilizada, o modelo de tumor de Walker 256 na vagina apresenta pega de 100% quando associado a ácido acético e não há diferença de comportamento com a inoculação de 4x10(6ou 2x10(6 células.

Nara Macedo Botelho Brito

2007-12-01

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Experimental inoculation model of Walker 256 carcinoma into vagina and cervix uteri of female rats / Modelo experimental de Tumor de Walker 256 em vagina e colo de útero de ratas  

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Full Text Available SciELO Brazil | Language: English Abstract in portuguese OBJETIVO: Estabelecer um modelo de inoculação de Tumor de Walker 256 em vagina e colo de útero de ratas. MÉTODOS: Foram utilizadas 15 ratas fêmeas, virgens, adultas, pesando entre 200-250g, distribuídas em três grupos de estudo com cinco animais cada: grupo A (GA): ratas com tumor de Walker 256 em c [...] oncentração de 4x10(6) sem ácido acético; grupo B (GB): ratas com tumor de Walker 256 em concentração de 2x10(6) células com ácido acético; grupo C (GC): ratas com tumor de Walker 256 em concentração de 4x10(6) células com ácido acético. No dia anterior à inoculação do tumor, foi realizada a inoculação de 0,3 ml de ácido acético a 10% na vagina das ratas de GB e GC; no dia seguinte, tanto estas como as ratas do grupo GA foram anestesiadas, feita a escarificação da parede vaginal com uma escova de endocérvice e inoculado 0,3ml de tumor na concentração de 4x10(6) células nos grupos GA e GC e 2x10(6) células no grupo GB. Após 12 dias, foi realizada a eutanásia e removido o tumor em bloco com vagina e cornos uterinos para análise, sendo pesado e averiguado seu volume e calculado as relações entre o seu peso e o peso final da rata e o seu volume e o peso final da rata. Os dados foram colhidos e submetidos à análise estatística pelo método ANOVA (um critério). RESULTADOS: A pega em GB e GC foi 100% e em GA 20%. Não houve diferença estatística entre as médias obtidas entre GB e GC. CONCLUSÃO: De acordo com a metodologia utilizada, o modelo de tumor de Walker 256 na vagina apresenta pega de 100% quando associado a ácido acético e não há diferença de comportamento com a inoculação de 4x10(6)ou 2x10(6) células. Abstract in english PURPOSE: To establish an inoculation model of Walker 256 carcinoma on cervix uteri and vagina of rats. METHODS: Fifteen female rats were used, and assigned to three groups each one with five rats: group A - rats with 4x10(6) cells of Walker 256 carcinoma without acid acetic inoculation; group B - ra [...] ts with 2x10(6) cells of Walker 256 carcinoma with acid acetic inoculation and group C: rats with 4x10(6) cells of Walker 256 carcinoma with acid acetic inoculation. The day before tumor cells inoculation the rats from groups B and C were anaesthetized with diethylether and 0,3 ml of acetic acid was inoculated into their vaginas. Tumor cell inoculation into the vagina and cervix was done under general anesthesia with diethylether. Then a endocervical brush was used to scrape the vaginal wall and after that 0,3 ml of the liquid containing tumor cells was inoculated on the vagina and cervix. For the tumor analysis, animals were euthanized at day 12 following tumor cell implantation by an excessive inhalation of diethylether. Tumor was resected entirely and weighed and the tumors were then sectioned and counter stained with hematoxylin and eosin for histopathologic evaluation. It was also calculated the percentage of tumor equivalent to the body weight by the formula: P= tumor weight / body weight x 100. Data were analyzed by one-way analysis of variance - ANOVA. P values

Nara Macedo Botelho, Brito; Marcus Vinicius Henriques, Brito; Rita de Kássia Vidigal, Carvalho; Lia Tavares de Moura Brasil, Matos; Thiago Sousa, Veloso; Diego Matos de, Vasconcelos; Rosângela Baía, Brito.

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Squamous carcinoma of the vagina: treatment, complications, and long-term follow-up  

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Seventy-five cases of primary squamous cell carcinoma of the vagina treated at the University of Pennsylvania are reviewed with long-term follow-up presented. These comprised 2.5% of all female genital malignancies treated during 1958 to 1980 inclusive. Patients treated during that time with non-squamous cell cancers have been excluded. Patients are analyzed with regard to stage, therapy, complications, and survival. Sixty-five percent of patients were stage I or II. Five-year survival for the entire group was 45%. Patients treated with radical surgery other than exenteration did well, with 7 of 8 surviving 5 years. Serious treatment complications were mostly related to radiation therapy and primarily involved the bowel and bladder. Three patients died of complications. Recurrence carried a grave prognosis as 30 of 33 patients with recurrence died of disease. Most recurrences were diagnosed within the first year following treatment. Patients with advanced disease were more likely to have distant recurrences. Although radiation therapy is generally the treatment of choice, radical surgery can yield excellent results when used in carefully selected patients. With meticulous attention to radiation dosage and technique it is hoped that treatment morbidity can be reduced. Optimal treatment of advanced disease may require some form of adjuvant systemic therapy

56

[Streptococcus agalactiae (GBS)--the characteristic of isolated strains from productive women's vagina].  

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The main aim of my research: to determine the frequency of colonisation Streptococcus agalactiae from productive women's vagina, an evaluation of usefulness microbiological diagnostic methods to detect GBS, to define serotype of analysed strains of S. agalactiae. After all, I tried to define fenotypic differential, biochemical and antimicrobial susceptibility between GBS with and without hemolysis. All of strains S. agalactiae (n = 380) belong to bacteria Gram(+), they had B serologic group and didn't produce catalase. On the basis of TSA+5% sheep blood streptococcus with beta-hemolysis grew like a small, grey and shiny colonies with a narrow, bright ring. On the same base we had S. agalactiae without beta-hemolysis, in examine material--6% (n = 22). On the basis of Strepto B ID S. agalactiae grew like a small, round red colonies and on the base Granada agar like an orange, white colonies. The level of colonisation S. agalactiae was 22% (380GBS/1727women). Identification of analysed strains of S. agalactiae was made by test API 20 Strep. The susceptibility was examined to ampicilin, azithromycin, erythromycin, clindamycin, chloramphenicol, doxycyclin, cotrimoxasol, ciprofloxacin. Serotypes III (50%), Ia (18%) and V (14%) prevailed. PMID:20873487

Wolny, Katarzyna; Go?da-Matuszak, Ewa

2010-01-01

57

Radiotherapy of primary carcinoma of the vagina: Clinical and histopathological variables associated with survival  

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434 cases of primary vaginal carcinoma were treated from 1950 to 1984 at the Irradiation Department of the University Clinic for Obstetrics and Gynecology, Vienna. The five-year survival rate for various clinical stages is as follows: Stage I 76.7%, stage II 44.5%, stage III 31%, stage IV 18.2%. In this retrospective study 110 patients seen from 1975 to 1984 were reviewed in detail and evaluated with a view toward their clinical and morphological aspects and survival rates. Patients up to the age of 60 have a five-year survival rate of 50%, those over 75 years of age reach only 34.3%. If the carcinoma was discovered in a routine check up the survival rate is 61.1%, whereas in cases with symptoms the rate decreases to 36.9%. Survival differences were also observed for patients with a carcinoma in the upper third of the vagina (61.1%) versus patients with a carcinoma in the lower third (33.3%); for patients with well-differentiated tumours (62.5%) versus patients with grades II and III (41.5% and 34.9%). It can be seen, that with brachytherapy local control of the carcinoma can be achieved with excellent results in early stages. Treatment of patients with more advanced carcinomas should include external beam therapy. The importance of gynecological screening especially for older women is emphasized. (orig.)

58

Recurrent paediatric pinworm infection of the vagina as a potential reservoir for Enterobius vermicularis.  

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Enterobius vermicularis infection remains one of the most common parasitic infections, particularly prevalent in children. Enterobiasis, although not usually dangerous, may cause significant morbidity. Elimination of the parasite from a family or an institution often poses problems, either because of an incomplete cure or re-infection. While there have been limited reports of ectopic enterobiasis throughout the world, ours is probably one of the rarest reports of recurrent vaginal E. vermicularis infection in the absence of any gastrointestinal symptoms despite complete treatment. A 4-year-old girl presented with recurrent episodes of vulval itching on 3-4 occasions over 2 years. There was no pruritis ani nor urinary/gastrointestinal complaints. The vulva was inflamed with 4-5 living worms, 6-7 mm in length, emerging from the anterior vaginal fornix, but with no vaginal discharge. Direct microscopic examination of vaginal swabs revealed adult worms of Enterobius but no eggs. Repeated stool samples from the patient, parents and a sibling were negative. The patient was treated orally with 100 mg of mebendazole for 3 days followed by two more courses at 3-week intervals over a period of 3 months. Recurrent vaginal enterobiasis despite complete treatment and in the absence of any gastrointestinal involvement suggests that the vagina is a potential reservoir for E. vermicularis, which supports the theory of rare ectopic enterobiasis through the ascending pathway of the female genital tract. PMID:23721910

Kashyap, B; Samantray, J C; Kumar, S; Jhamb, R; Singh, A K; Kaur, I R

2014-09-01

59

Nevoid melanoma of the vagina: report of one case diagnosed on thin layer cytological preparations  

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Full Text Available Abstract Background Primary melanoma of the vagina is an extremely rare neoplasm with approximately 250 reported cases in the world literature 1234. In its amelanotic variant this lesion may raise several differential diagnostic problems in cytological specimens 5. In this setting, the usage of thin layer cytopathological techniques (Liquid Based Preparations = LBP may enhance the diagnostic sensitivity by permitting immunocytochemical study without having to repeat the sampling procedure. The aim of this paper is to describe the cytomorphological presentation of primary vaginal melanoma on LBP since it has not previously been reported up to now, to our knowledge. Case presentation a 79-y-o female complaining of vulvar itching and yellowish vaginal discharge underwent a complete gynaecological evaluation during which a LBP cytological sample was taken from a suspicious whitish mass protruding into the vaginal lumen. A cytopathological diagnosis of amelanotic melanoma was rendered. The mass was radically excised and the patient was treated with ?-Interferon. Conclusion amelanotic melanoma may be successfully diagnosed on LBP cytological preparations. Thin layer preparations may enhance the diagnostic cytomorphological clues to its diagnosis and may permit an adequate immunocytochemical characterization of the neoplasm.

Ascierto Paolo

2007-01-01

60

p21 and Notch signalings in the persistently altered vagina induced by neonatal diethylstilbestrol exposure in mice.  

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Female reproductive organs show organ-specific morphological changes during estrous cycles. Perinatal exposure to natural and synthetic estrogens including diethylstilbestrol (DES) or estrogenic chemicals induces estrogen-independent persistent proliferation of vaginal epithelium in mice. To understand the underlying mechanism of the estrogen-independent persistent vaginal changes induced by perinatal DES exposure, we examined global gene expressions in the vaginae of ovariectomized adult mice exposed neonatally to DES using a microarray. The cell cycle-related gene, p21, a cyclin-dependent kinase inhibitor, showed upregulation in the vagina, and p21 protein was localized in the basal layer of the vaginal epithelium in mice exposed neonatally to DES and an estrogen receptor ? agonist, propyl pyrazole triol (PPT). The expressions of Notch receptors and Notch ligands were unchanged; however, the mRNAs of hairy-related basic helix-loop-helix (bHLH) transcription factor genes, Hes1, Hey1 and Heyl were persistently downregulated in the vagina, indicating estrogen-independent epithelial cell proliferation in mice exposed neonatally to DES and PPT. PMID:22850433

Nakamura, Takeshi; Miyagawa, Shinichi; Katsu, Yoshinao; Mizutani, Takeshi; Sato, Tomomi; Takeuchi, Takashi; Iguchi, Taisen; Ohta, Yasuhiko

2012-12-01

 
 
 
 
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Internal artificial vagina (IAV) to assess breeding behavior of young Bos taurus and Bos indicus bulls.  

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Bull breeding soundness evaluation (BBSE) usually neglects the libido and mating ability evaluation. The internal artificial vagina (IAV) permits semen sampling, as well as mating ability evaluation. Few studies have been performed using IAV with young bulls and there are none with Bos indicus bulls. The present study evaluated sexual behavior, mating ability and semen quality in young Bos taurus (Devon) and B. indicus (Nellore) bulls using the IAV device. In the first experiment, 52 Devon bulls, 18-25 months old were observed, and the behavior and mating ability recorded over a 10-min period within a restrained mount-cow with an IAV inserted. In the second experiment, 20 Nellore bulls, 20-30 months old were evaluated over a 20 min period. Of the 52 Devon bulls, 45 (86.5%) had semen recovered with the IAV, 31 (69.0%) were considered satisfactory. Nellore bulls exhibited a different sexual behavior, with 10 bulls not showing any interest in the females. Four bulls demonstrated sexual interest only once, e.g., sniffing, two showed interest on more than one occasion, and four had more than two mounts or mounting attempts. None out of the Nellore bulls was collected with IAV. The IAV was an effective and welfare-promoting animal technology for the evaluation of semen quality and mating ability of B. taurus bulls. However, the IAV was not adequate for young Nellore bulls, probably due to their quiescent sexual behavior and delayed sexual maturity. Further studies are needed to evaluate the performance of the IAV for older Nellore bulls. PMID:21733646

Cruz, F B; Lohn, L; Marinho, L S R; Mezzalira, J C; Neto, S Gaudencio; Martins, L T; Vieira, A D; Barth, A; Mezzalira, A

2011-07-01

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xpression of estrogen and progesterone receptor genes in endometrium, myometrium and vagina of postmenopausal women treated with estriol / Expresión de los genes receptores de estrógeno y progesterona en el endometrio, miometrio y vagina en mujeres posmenopáusicas tratadas con estriol  

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Full Text Available SciELO Brazil | Language: English Abstract in spanish CONTEXTO Y OBJETIVO: El estriol es un estrógeno con un efecto estimulatorio bastante más débil sobre la proliferación endometrial que el estradiol. Se realizó un estudio para determinar los efectos de una terapia vaginal de 14 días con estriol, sobre el nivel de receptores de estrógeno (ER) y recept [...] ores de progesterona (PR), comparado con mujeres sin esa terapia. La expresión de los genes de ER y PR se analizó en el endometrio, miometrio y vagina de mujeres posmenopáusicas tratadas con estriol. DISEÑO Y UBICACIÓN: Estudio Transversal analítico, en el Instituto de Investigación del Hospital de la Madre Polaca en Lodz, Polonia. MÉTODOS: Se incluyeron veintisiete mujeres posmenopáusicas (de 57 a 74 años) en el estudio. Todas ellas estaban en espera de una histerectomía per vaginam o de cirugía plástica de la vagina y del perineo debido a un prolapso del útero. La expresión de genes de los receptores ER y PR se estableció por la técnica de RT-PCR. RESULTS: En las pacientes tratadas con estriol en comparación con el grupo de control, se observó un aumento significativo de la expresión del gen de ER en el endometrio y la vagina, mientras que un aumento de la expresión del gen de PR se encontró en el endometrio. De todas formas, en el examen histológico del endometrio, se diagnosticó estimulación estrogénica de bajo y medio grado en el 21.4% y en el 14.3% de las mujeres tratadas con estriol, respectivamente. CONCLUSIONES: Los resultados obtenidos sugieren que un tratamiento de 14 días con estriol en pacientes, aunque aumentan el nivel de ER y de PR mRNA, tiene muy poco o ningún efecto sobre la proliferación endometrial. Abstract in english CONTEXT AND OBJECTIVE: Estriol is an estrogen with considerably weaker stimulatory effects on endometrial proliferation than estradiol. A study was conducted to determine the level of estrogen receptors (ERs) and progesterone receptors (PRs) in women who received 14-day vaginal estriol therapy, comp [...] ared with those who did not receive this therapy. ER and PR gene expression was analyzed in the endometrium, myometrium and vagina of postmenopausal women treated with estriol. DESIGN AND SETTING: Analytical cross-sectional study, at the Research Institute of the Polish Mothers' Memorial Hospital, Lodz, Poland. METHODS: Twenty-seven postmenopausal women (57-74 years of age) were included in the study. All of them were waiting for per vaginam hysterectomy or plastic surgery on the vagina and perineum because of uterine prolapse. ER and PR gene expression was determined by means of the technique of reverse transcription polymerase chain reaction (RT-PCR). RESULTS: In the estriol-treated patients, in comparison with the control group, a significant increase in ER gene expression was observed in the endometrium and vagina, while enhanced PR gene expression was found in the endometrium. However, under histological examination of the endometrium, estrogen stimulation of low and medium degree was diagnosed for 21.4% and 14.3% of the estriol-treated women, respectively. CONCLUSION: The results obtained suggest that the women who received 14 days of treatment with vaginal estriol had higher ER and PR mRNA levels. No difference between these groups regarding endometrial proliferation was observed.

Magdalena, Bry& #347; ; Krzysztof, Szytto; Hanna, Romanowicz-Makowska; Zbigniew, Dobrowolski; Izabela, Mastowska; Wanda, Krajewska.

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Avaliação dosimétrica de uma combinação de aplicadores para braquiterapia de tumores do colo uterino com acometimento da porção distal da vagina Dosimetric evaluation of a combination of brachytherapy applicators for uterine cervix cancer with involvement of the distal vagina  

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Full Text Available OBJETIVO: Avaliar uma alternativa de braquiterapia para tumores do colo uterino acometendo a porção distal da vagina, sem aumentar os riscos de toxicidade. MATERIAIS E MÉTODOS: Estudo teórico comparando três diferentes aplicadores de braquiterapia intracavitária de alta taxa de dose: sonda intrauterina e cilindro vaginal (SC; sonda e anel associado ao cilindro vaginal (SA+C e um aplicador virtual com sonda, anel e cilindro vaginal em um único conjunto (SAC. Foram prescritas doses de 7 Gy no ponto A e 5 Gy na superfície ou a 5 mm de profundidade na mucosa vaginal, mantendo as doses nos pontos de reto, bexiga e sigmoide abaixo dos limites de tolerância. Foram comparados os volumes englobados pelas isodoses de 50% (V50, 100% (V100, 150% (V150 e 200% (V200, respectivamente. RESULTADOS: Tanto SA+C quanto SAC apresentaram melhor distribuição de dose quando comparados ao aplicador SC. A distribuição de dose obtida com SA+C foi semelhante à do aplicador SAC, sendo V150 e V200 cerca de 50% maiores para SA+C, todavia, dentro do cilindro. CONCLUSÃO: A utilização de SA+C em uma única aplicação em dois tempos pode ser uma alternativa de tratamento para pacientes que apresentam tumores de colo uterino com acometimento distal da vagina.OBJECTIVE: To evaluate an alternative brachytherapy technique for uterine cervix cancer involving the distal vagina, without increasing the risk of toxicity. MATERIALS AND METHODS: Theoretical study comparing three different high-dose rate intracavitary brachytherapy applicators: intrauterine tandem and vaginal cylinder (TC; tandem/ring applicator combined with vaginal cylinder (TR+C; and a virtual applicator combining both the tandem/ring and vaginal cylinder in a single device (TRC. Prescribed doses were 7 Gy at point A, and 5 Gy on the surface or at a 5 mm depth of the vaginal mucosa. Doses delivered to the rectum, bladder and sigmoid colon were kept below the tolerance limits. Volumes covered by the isodoses, respectively, 50% (V50, 100% (V100, 150% (V150 and 200% (V200 were compared. RESULTS: Both the combined TR+C and TRC presented a better dose distribution as compared with the TC applicator. The TR+C dose distribution was similar to the TRC dose, with V150 and V200 being about 50% higher for TR+C (within the cylinder. CONCLUSION: Combined TR+C in a two-time single application may represent an alternative therapy technique for patients affected by uterine cervix cancer involving the distal vagina.

Roger Guilherme Rodrigues Guimarães

2009-08-01

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Avaliação dosimétrica de uma combinação de aplicadores para braquiterapia de tumores do colo uterino com acometimento da porção distal da vagina / Dosimetric evaluation of a combination of brachytherapy applicators for uterine cervix cancer with involvement of the distal vagina  

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Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese OBJETIVO: Avaliar uma alternativa de braquiterapia para tumores do colo uterino acometendo a porção distal da vagina, sem aumentar os riscos de toxicidade. MATERIAIS E MÉTODOS: Estudo teórico comparando três diferentes aplicadores de braquiterapia intracavitária de alta taxa de dose: sonda intrauter [...] ina e cilindro vaginal (SC); sonda e anel associado ao cilindro vaginal (SA+C) e um aplicador virtual com sonda, anel e cilindro vaginal em um único conjunto (SAC). Foram prescritas doses de 7 Gy no ponto A e 5 Gy na superfície ou a 5 mm de profundidade na mucosa vaginal, mantendo as doses nos pontos de reto, bexiga e sigmoide abaixo dos limites de tolerância. Foram comparados os volumes englobados pelas isodoses de 50% (V50), 100% (V100), 150% (V150) e 200% (V200), respectivamente. RESULTADOS: Tanto SA+C quanto SAC apresentaram melhor distribuição de dose quando comparados ao aplicador SC. A distribuição de dose obtida com SA+C foi semelhante à do aplicador SAC, sendo V150 e V200 cerca de 50% maiores para SA+C, todavia, dentro do cilindro. CONCLUSÃO: A utilização de SA+C em uma única aplicação em dois tempos pode ser uma alternativa de tratamento para pacientes que apresentam tumores de colo uterino com acometimento distal da vagina. Abstract in english OBJECTIVE: To evaluate an alternative brachytherapy technique for uterine cervix cancer involving the distal vagina, without increasing the risk of toxicity. MATERIALS AND METHODS: Theoretical study comparing three different high-dose rate intracavitary brachytherapy applicators: intrauterine tandem [...] and vaginal cylinder (TC); tandem/ring applicator combined with vaginal cylinder (TR+C); and a virtual applicator combining both the tandem/ring and vaginal cylinder in a single device (TRC). Prescribed doses were 7 Gy at point A, and 5 Gy on the surface or at a 5 mm depth of the vaginal mucosa. Doses delivered to the rectum, bladder and sigmoid colon were kept below the tolerance limits. Volumes covered by the isodoses, respectively, 50% (V50), 100% (V100), 150% (V150) and 200% (V200) were compared. RESULTS: Both the combined TR+C and TRC presented a better dose distribution as compared with the TC applicator. The TR+C dose distribution was similar to the TRC dose, with V150 and V200 being about 50% higher for TR+C (within the cylinder). CONCLUSION: Combined TR+C in a two-time single application may represent an alternative therapy technique for patients affected by uterine cervix cancer involving the distal vagina.

Roger Guilherme Rodrigues, Guimarães; Heloisa de Andrade, Carvalho; Silvia Radwanski, Stuart; Rodrigo Augusto, Rubo; Rodrigo Migotto, Seraide.

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Dosimetric evaluation of a combination of brachytherapy applicators for uterine cervix cancer with involvement of the distal vagina; Avaliacao dosimetrica de uma combinacao de aplicadores para braquiterapia de tumores do colo uterino com acometimento da porcao distal da vagina  

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Objective: To evaluate an alternative brachytherapy technique for uterine cervix cancer involving the distal vagina, without increasing the risk of toxicity. Materials And Methods: Theoretical study comparing three different high-dose rate intracavitary brachytherapy applicators: intrauterine tandem and vaginal cylinder (TC); tandem/ring applicator combined with vaginal cylinder (TR+C); and a virtual applicator combining both the tandem/ring and vaginal cylinder in a single device (TRC). Prescribed doses were 7 Gy at point A, and 5 Gy on the surface or at a 5 mm depth of the vaginal mucosa. Doses delivered to the rectum, bladder and sigmoid colon were kept below the tolerance limits. Volumes covered by the isodoses, respectively, 50% (V50), 100% (V100), 150% (V150) and 200% (V200) were compared. Results: Both the combined TR+C and TRC presented a better dose distribution as compared with the TC applicator. The TR+C dose distribution was similar to the TRC dose, with V150 and V200 being about 50% higher for TR+C (within the cylinder). Conclusion: Combined TR+C in a two-time single application may represent an alternative therapy technique for patients affected by uterine cervix cancer involving the distal vagina. (author)

Guimaraes, Roger Guilherme Rodrigues [Real e Benemerita Sociedade Portuguesa de Beneficencia, Sao Paulo, SP (Brazil). Servico de Radioterapia Estereotactica; Carvalho, Heloisa de Andrade; Stuart, Silvia Radwanski; Rubo, Rodrigo Augusto [Universidade de Sao Paulo (USP), SP (Brazil). Hospital das Clinicas. Servico de Radioterapia], e-mail: handrade@hcnet.usp.br; Seraide, Rodrigo Migotto [Centro de Oncologia Campinas, SP (Brazil)

2009-07-15

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The effect of copaiba balsam on Walker 256 carcinoma inoculated into the vagina and uterine cervix of female rats Efeito do óleo de copaíba no tumor de Walker 256 inoculado em vagina e colo de útero de ratas fêmeas  

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Full Text Available PURPOSE: To verify the copaiba balsam (Copaifera officinalis effect on Walker 256 carcinoma inoculated into vagina and uterine cervix of rats. METHODS: Eighteen female Wistar rats weighing between 180-250g were used, distributed into 2 groups (GCop, GC. On the 1st day of the experiment, 0.3 ml of Walker 256 carcinoma (2x10(6 concentration was inoculated in both groups; on the 3rd day of the experiment, it was given 4.8 ml/kg of distilled water to the GC group, and 4.8 ml/kg of copaiba balsam to the GCop group. On the 12th day, euthanasia was performed and the tumor was grafted, being weighted and verified its volume. The data were submitted to statistical analysis with ANOVA test. RESULTS: It was observed that copaiba balsam presented a negative inhibitory potential of 70%. CONCLUSION: The copaiba balsam stimulated the tumor growth.OBJETIVO: Verificar o efeito do óleo de copaíba da espécie Copaifera officinalis no carcinoma de Walker 256 inoculado em vagina e colo de útero de ratas. MÉTODOS: Foram utilizadas 18 ratas da linhagem Wistar, pesando entre 180-250g, distribuídas em dois grupos (CCop, GC. No 1º dia de experimento, em ambos os grupos foi inoculado 0,3ml de tumor de Walker 256 na concentração de 2x10(6; no 3º dia após essa inoculação, foi iniciada a administração de água destilada na dose de 4,8 ml/kg ao GC, e copaíba na dose de 4,8 ml/kg ao GCop. No 12º dia foi realizada a eutanásia das ratas e ressecado o tumor, sendo este pesado e averiguado seu volume. Os dados obtidos foram submetidos à análise estatística pelo método ANOVA. RESULTADOS: Observou-se que o óleo de copaíba apresentou um potencial inibitório negativo de 70%. CONCLUSÃO: O óleo de copaíba estimulou o crescimento tumoral.

Nara Macedo Botelho Brito

2010-04-01

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Ultrastructural study of the neovagina following the utilization of human amniotic membrane for treatment of congenital absence of the vagina  

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Full Text Available SciELO Brazil | Language: English Abstract in english We present an ultrastructural study of the utilization of human amniotic membrane in the treatment of congenital absence of the vagina in 10 patients. All patients were surgically treated with application of an amniotic membrane graft using the modified McIndoe and Bannister technique. Sixty days af [...] ter surgery, samples of the vaginal neo-epithelium were collected for transmission electron microscopy analysis. The ultrastructural findings consisted of a lining of mature squamous epithelium indicating the occurrence of metaplasia of the amniotic epithelium into the vaginal epithelium. The cells were arranged in layers as in the normal vaginal epithelium, i.e., superficial, intermediate and deep layers. There were desmosomes and cytoplasmic intermediate cytokeratin filaments, as well as some remnant features of the previous amniotic epithelium. These findings suggest that human amniotic membrane is able to complete metaplasia into squamous cells but the mechanism of this cellular transformation is unknown

L.F., Bleggi-Torres; B., Werner; M.J., Piazza.

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Genital panics: constructing the vagina in women's qualitative narratives about pubic hair, menstrual sex, and vaginal self-image.  

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An emerging body of research targets women's relationship to their genitals, particularly as pubic hair removal and the promotion of female genital surgeries increase in popularity and visibility. This study asked women to discuss their subjective feelings about three related but distinct genital attitudes: pubic hair grooming, sex during menstruation, and genital/vaginal self-image. Specifically, this study applied thematic analysis to qualitative interviews with a community sample of 20 women (mean age=34, SD=13.35) from diverse ages, races, and sexual identity backgrounds to illuminate seven themes in women's narratives about their vaginas: (1) "dirty" or "gross"; (2) needing maintenance; (3) unknown or frustrating; (4) unnatural; (5) comparative; (6) ambivalent; (7) affirmative. Overwhelmingly, women used strong emotional language when discussing their genitals, often evoking descriptions of anxiety, excess, and need for control. Fusions between sexuality and body image, and connections between "genital panics" and internalized racism, sexism, and homophobia, also appeared. PMID:24958655

Fahs, Breanne

2014-06-01

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Phasic Contractions of the Mouse Vagina and Cervix at Different Phases of the Estrus Cycle and during Late Pregnancy  

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Background/Aims The pacemaker mechanisms activating phasic contractions of vaginal and cervical smooth muscle remain poorly understood. Here, we investigate properties of pacemaking in vaginal and cervical tissues by determining whether: 1) functional pacemaking is dependent on the phase of the estrus cycle or pregnancy; 2) pacemaking involves Ca2+ release from sarcoplasmic/endoplasmic reticulum Ca2+-ATPase (SERCA) -dependent intracellular Ca2+ stores; and 3) c-Kit and/or vimentin immunoreactive ICs have a role in pacemaking. Methodology/Principal Findings Vaginal and cervical contractions were measured in vitro, as was the distribution of c-Kit and vimentin positive interstitial cells (ICs). Cervical smooth muscle was spontaneously active in estrus and metestrus but quiescent during proestrus and diestrus. Vaginal smooth muscle was normally quiescent but exhibited phasic contractions in the presence of oxytocin or the K+ channel blocker tetraethylammonium (TEA) chloride. Spontaneous contractions in the cervix and TEA-induced phasic contractions in the vagina persisted in the presence of cyclopiazonic acid (CPA), a blocker of the SERCA that refills intracellular SR Ca2+ stores, but were inhibited in low Ca2+ solution or in the presence of nifedipine, an inhibitor of L-type Ca2+channels. ICs were found in small numbers in the mouse cervix but not in the vagina. Conclusions/Significance Cervical smooth muscle strips taken from mice in estrus, metestrus or late pregnancy were generally spontaneously active. Vaginal smooth muscle strips were normally quiescent but could be induced to exhibit phasic contractions independent on phase of the estrus cycle or late pregnancy. Spontaneous cervical or TEA-induced vaginal phasic contractions were not mediated by ICs or intracellular Ca2+ stores. Given that vaginal smooth muscle is normally quiescent then it is likely that increases in hormones such as oxytocin, as might occur through sexual stimulation, enhance the effectiveness of such pacemaking until phasic contractile activity emerges. PMID:25337931

Gravina, Fernanda S.; van Helden, Dirk F.; Kerr, Karen P.; de Oliveira, Ramatis B.; Jobling, Phillip

2014-01-01

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Sequential changes in the expression of Wnt- and Notch-related genes in the vagina and uterus of ovariectomized mice after estrogen exposure.  

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Estrogen regulates morphological changes in reproductive organs, such as the vagina and uterus, during the estrous cycles in mice. Estrogen depletion by ovariectomy in adults results in atrophy accompanied by apoptosis in vaginal and uterine cells, while estrogen treatment following ovariectomy elicits cell proliferation in both organs. Sequential changes in mRNA expression of wingless-related MMTV integration site (Wnt) and Notch signaling genes were analyzed in the vagina and uterus of ovariectomized adult mice after a single injection of 17?-estradiol to provide understanding over the molecular basis of differences in response to estrogen in these organs. We found estrogen-dependent up-regulation of Wnt4, Wnt5a and p21 and down-regulation of Wnt11, hairy/enhancer-of-split related with YRPW motif-1 (Hey1) and delta-like 4 (Dll4) in the vagina, and up-regulation of Wnt4, Wnt5a, Hey1, Heyl, Dll1, p21 and p53 and down-regulation of Wnt11, Hey2 and Dll4 in the uterus. The expression of Wnt4, Hey1, Hey2, Heyl, Dll1 and p53 showed different patterns after the estrogen injection. Expression patterns for Wnt5a, Wnt11, Dll4 and p21 in the vagina and uterus were similar, suggesting that these genes are involved in the proliferation of cells in both those organs in mice. PMID:23160670

Nakamura, Takeshi; Miyagawa, Shinichi; Katsu, Yoshinao; Sato, Tomomi; Iguchi, Taisen; Ohta, Yasuhiko

2012-01-01

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Risk factors for invasive squamous cell carcinoma of the vulva and vagina--population-based case-control study in Denmark.  

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The etiology of vulvar and vaginal squamous cell carcinoma (VV-SCC) has received little attention. A total of 182 women with invasive VV-SCC (116 with VV-SCC(vulva), 66 with VV-SCC(vagina)), 164 uterine corpus cancer controls and 518 population controls were interviewed in a population-based case-control study in Denmark, and 87 (48%) of the VV-SCC cases had tissue samples examined for human papillomavirus (HPV) DNA using the GP5+/6+ PCR-EIA assay and subsequent reverse line blotting for HPV typing. Logistic regression-derived odds ratios with 95% confidence intervals served as relative risks. Cervical cancer-associated high-risk HPVs (hrHPVs) were detectable in most (89%) examined cases of VV-SCC(vagina) and in half (50%) of cases of VV-SCC(vulva) (p risk factors for both VV-SCC(vulva) and VV-SCC(vagina) included measures of hrHPV exposure (anogenital warts for VV-SCC(vulva); cervical neoplasia and poor genital hygiene for VV-SCC(vagina)), tobacco smoking and alcohol consumption. Furthermore, socioeconomic variables (marital status and years at school) were associated with risk of VV-SCC(vulva). Comparing hrHPV-positive and hrHPV-negative VV-SCCs in polytomous logistic regression analysis revealed that tobacco smoking and cervical neoplasia were significant risk factors only for hrHPV-positive VV-SCCs. Our study shows that VV-SCC(vulva) and VV-SCC(vagina) share measures of prior hrHPV exposure, tobacco smoking and alcohol consumption as statistically significant risk factors. HPV vaccination programs aimed at reducing the burden of cervical cancers are likely to also provide considerable protection against VV-SCCs. PMID:18348142

Madsen, Birgitte S; Jensen, Helle L; van den Brule, Adriaan J C; Wohlfahrt, Jan; Frisch, Morten

2008-06-15

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Nonoxynol-9 berberine plural gel has little effect on expression of SLPI, SP-D and lactoferrin in mice’s vagina  

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Full Text Available Background: The most frequently used spermicide Nonoxynol-9 (N-9 in the clinic alters the vaginal flora, which will result in an increased risk of opportunistic infection. So development of a novel spermicidal and microbicidal drug appears to be inevitable. Vaginal local immune is an important part of vaginal flora. Secretory leukocyte protease inhibitor (SLPI, surfactant proteins D (SP-D, and lactoferrin (LF are anti-microbial molecules with important roles in immune system of female vaginas. Objective: To observe effect of a vaginal spermicide nonoxynol-9 (N-9 berberine plural gel on the expression of SLPI SP-D and LF in mice’s vaginas. Materials and Methods: Female BABL/C mice were randomly divided into following 5 groups: normal control group, blank gel group, berberine gel group, 12% N-9 gel group and N-9 berberine plural gel group. Estradiol benzoate at physiological dose was done by hypodermic injection to every group’s mice. After 72h, drug gels were separately injected into the mice’s vaginas, while immunohistochemistry and Western blot were taken to detect the expression of the 3 indexes in mice’s vaginas respectively after 24h and 72h of gel injection. Results: The differences in the three indexes between normal control group and blank gel group were not significant statistically (p>0.05. The expression of the three indexes in 12% N-9 gel group was decreased compared to that in blank gel group (p0.05. Also, the three index's level of 24h and 72h in sub observation groups after treatment were without statistical significance (p>0.05. Conclusion: Application of N-9 berberine plural gel had little impact on antimicrobial peptides in normal mice’s vaginas.

Huang Guangying

2013-01-01

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Caracterização de leveduras isoladas da vagina e sua associação com candidíase vulvovaginal em duas cidades do sul do Brasil Characterization of yeasts isolated from the vagina and their association with vulvovaginal candidíasis in two cities of the South of Brazil  

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Full Text Available OBJETIVOS: avaliar a distribuição de espécies de leveduras isoladas da vagina em duas localidades do sul do Brasil e comparar o perfil de suscetibilidade in vitro destas leveduras a antifúngicos usados na prática clínica. MÉTODOS: todas as mulheres atendidas entre janeiro e junho de 2004 para exames rotineiros de amostras vaginais, independente de serem sintomáticas ou não, foram incluídas neste estudo. Foram excluídas as que apresentavam imunodeficiências como AIDS ou outras infecções genitais. Amostras de conteúdo vaginal dessas mulheres (Jaraguá do Sul - SC (n=130 e Maringá - PR (n=97 foram cultivadas. As leveduras isoladas foram identificadas e submetidas ao teste de suscetibilidade aos antifúngicos fluconazol, nistatina e anfotericina B. RESULTADOS: a freqüência de cultura positiva para levedura foi semelhante nas duas localidades, aproximadamente 24%. Candida albicans foi a espécie prevalente, mas sua freqüência diferiu: em SC correspondeu a 77,4% das leveduras e foi a mais freqüente tanto nas mulheres sintomáticas quanto nas assintomáticas. Já no PR foi 50,0%, com predomínio mais evidente nos casos sintomáticos. Observamos altos índices de suscetibilidade ao fluconazol e anfotericina B, porém 51,1% das leveduras apresentaram suscetibilidade dependente da dose (S-DD para nistatina. C. albicans mostrou maior tendência de resistência à nistatina (52,8% de S-DD do que as espécies não-albicans (44,4%. CONCLUSÕES: nossos dados mostram diferenças regionais quanto à espécie de levedura em amostras vaginais. Sugerem que a determinação da espécie pode ter implicação clínica, considerando as diferenças quanto à suscetibilidade, principalmente à nistatina, e que poderiam ter importância no manejo da candidíase vulvovaginal.PURPOSE: to evaluate the distribution of yeast species isolated from the vagina in two cities of the South of Brazil and compare the in vitro susceptibility profile of these yeasts against some antifungals, which are used in clinical routine. METHODS: all women attended from January to June 2004 for vaginal routine examinations, independent of being symptomatic or not were included in the study. Only those who presented immunodeficiency like AIDS or any other genital infection were excluded. Samples of vaginal discharge from the women (Jaraguá do Sul - SC (n=130 and Maringá - PR (n=97 were cultivated. The yeasts were identified and submitted to the susceptibility test against the antifungals fluconazole, nystatin and amphotericin B. RESULTS: the frequency of positive cultures for yeasts was the same in both cities; C. albicans was the most prevalent species (about 24%, but its frequency was different: in SC it corresponded to 77.4% of the yeasts both in symptomatic and asymptomatic women and in PR it was 50.0% with predominance in symptomatic women. We observed high rates of susceptibility to fluconazole and amphotericin B, but 51.1% of the yeasts presented dose-dependent susceptibility (DDS to nystatin. C. albicans showed a higher tendency to be nystatin resistant (52.8% DDS than non-albicans species (44.4%. CONCLUSIONS: our data showed geographic differences among the species of yeasts isolated from the vagina and suggest that this fact has clinical relevance considering the differences in susceptibility, especially regarding nystatin, which could be important for the management of vulvovaginal candidiasis.

Magda Helena S. H. Ferrazza

2005-02-01

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Caracterização de leveduras isoladas da vagina e sua associação com candidíase vulvovaginal em duas cidades do sul do Brasil / Characterization of yeasts isolated from the vagina and their association with vulvovaginal candidíasis in two cities of the South of Brazil  

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Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese OBJETIVOS: avaliar a distribuição de espécies de leveduras isoladas da vagina em duas localidades do sul do Brasil e comparar o perfil de suscetibilidade in vitro destas leveduras a antifúngicos usados na prática clínica. MÉTODOS: todas as mulheres atendidas entre janeiro e junho de 2004 para exames [...] rotineiros de amostras vaginais, independente de serem sintomáticas ou não, foram incluídas neste estudo. Foram excluídas as que apresentavam imunodeficiências como AIDS ou outras infecções genitais. Amostras de conteúdo vaginal dessas mulheres (Jaraguá do Sul - SC (n=130) e Maringá - PR (n=97)) foram cultivadas. As leveduras isoladas foram identificadas e submetidas ao teste de suscetibilidade aos antifúngicos fluconazol, nistatina e anfotericina B. RESULTADOS: a freqüência de cultura positiva para levedura foi semelhante nas duas localidades, aproximadamente 24%. Candida albicans foi a espécie prevalente, mas sua freqüência diferiu: em SC correspondeu a 77,4% das leveduras e foi a mais freqüente tanto nas mulheres sintomáticas quanto nas assintomáticas. Já no PR foi 50,0%, com predomínio mais evidente nos casos sintomáticos. Observamos altos índices de suscetibilidade ao fluconazol e anfotericina B, porém 51,1% das leveduras apresentaram suscetibilidade dependente da dose (S-DD) para nistatina. C. albicans mostrou maior tendência de resistência à nistatina (52,8% de S-DD) do que as espécies não-albicans (44,4%). CONCLUSÕES: nossos dados mostram diferenças regionais quanto à espécie de levedura em amostras vaginais. Sugerem que a determinação da espécie pode ter implicação clínica, considerando as diferenças quanto à suscetibilidade, principalmente à nistatina, e que poderiam ter importância no manejo da candidíase vulvovaginal. Abstract in english PURPOSE: to evaluate the distribution of yeast species isolated from the vagina in two cities of the South of Brazil and compare the in vitro susceptibility profile of these yeasts against some antifungals, which are used in clinical routine. METHODS: all women attended from January to June 2004 for [...] vaginal routine examinations, independent of being symptomatic or not were included in the study. Only those who presented immunodeficiency like AIDS or any other genital infection were excluded. Samples of vaginal discharge from the women (Jaraguá do Sul - SC (n=130) and Maringá - PR (n=97)) were cultivated. The yeasts were identified and submitted to the susceptibility test against the antifungals fluconazole, nystatin and amphotericin B. RESULTS: the frequency of positive cultures for yeasts was the same in both cities; C. albicans was the most prevalent species (about 24%), but its frequency was different: in SC it corresponded to 77.4% of the yeasts both in symptomatic and asymptomatic women and in PR it was 50.0% with predominance in symptomatic women. We observed high rates of susceptibility to fluconazole and amphotericin B, but 51.1% of the yeasts presented dose-dependent susceptibility (DDS) to nystatin. C. albicans showed a higher tendency to be nystatin resistant (52.8% DDS) than non-albicans species (44.4%). CONCLUSIONS: our data showed geographic differences among the species of yeasts isolated from the vagina and suggest that this fact has clinical relevance considering the differences in susceptibility, especially regarding nystatin, which could be important for the management of vulvovaginal candidiasis.

Magda Helena S. H., Ferrazza; Márcia L. Ferrarezi, Maluf; Marcia Edilaine Lopes, Consolaro; Cristiane Suemi, Shinobu; Terezinha Inez Estivalet, Svidzinski; Márcia Regina, Batista.

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Caracterização de leveduras isoladas da vagina e sua associação com candidíase vulvovaginal em duas cidades do sul do Brasil / Characterization of yeasts isolated from the vagina and their association with vulvovaginal candidíasis in two cities of the South of Brazil  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese OBJETIVOS: avaliar a distribuição de espécies de leveduras isoladas da vagina em duas localidades do sul do Brasil e comparar o perfil de suscetibilidade in vitro destas leveduras a antifúngicos usados na prática clínica. MÉTODOS: todas as mulheres atendidas entre janeiro e junho de 2004 para exames [...] rotineiros de amostras vaginais, independente de serem sintomáticas ou não, foram incluídas neste estudo. Foram excluídas as que apresentavam imunodeficiências como AIDS ou outras infecções genitais. Amostras de conteúdo vaginal dessas mulheres (Jaraguá do Sul - SC (n=130) e Maringá - PR (n=97)) foram cultivadas. As leveduras isoladas foram identificadas e submetidas ao teste de suscetibilidade aos antifúngicos fluconazol, nistatina e anfotericina B. RESULTADOS: a freqüência de cultura positiva para levedura foi semelhante nas duas localidades, aproximadamente 24%. Candida albicans foi a espécie prevalente, mas sua freqüência diferiu: em SC correspondeu a 77,4% das leveduras e foi a mais freqüente tanto nas mulheres sintomáticas quanto nas assintomáticas. Já no PR foi 50,0%, com predomínio mais evidente nos casos sintomáticos. Observamos altos índices de suscetibilidade ao fluconazol e anfotericina B, porém 51,1% das leveduras apresentaram suscetibilidade dependente da dose (S-DD) para nistatina. C. albicans mostrou maior tendência de resistência à nistatina (52,8% de S-DD) do que as espécies não-albicans (44,4%). CONCLUSÕES: nossos dados mostram diferenças regionais quanto à espécie de levedura em amostras vaginais. Sugerem que a determinação da espécie pode ter implicação clínica, considerando as diferenças quanto à suscetibilidade, principalmente à nistatina, e que poderiam ter importância no manejo da candidíase vulvovaginal. Abstract in english PURPOSE: to evaluate the distribution of yeast species isolated from the vagina in two cities of the South of Brazil and compare the in vitro susceptibility profile of these yeasts against some antifungals, which are used in clinical routine. METHODS: all women attended from January to June 2004 for [...] vaginal routine examinations, independent of being symptomatic or not were included in the study. Only those who presented immunodeficiency like AIDS or any other genital infection were excluded. Samples of vaginal discharge from the women (Jaraguá do Sul - SC (n=130) and Maringá - PR (n=97)) were cultivated. The yeasts were identified and submitted to the susceptibility test against the antifungals fluconazole, nystatin and amphotericin B. RESULTS: the frequency of positive cultures for yeasts was the same in both cities; C. albicans was the most prevalent species (about 24%), but its frequency was different: in SC it corresponded to 77.4% of the yeasts both in symptomatic and asymptomatic women and in PR it was 50.0% with predominance in symptomatic women. We observed high rates of susceptibility to fluconazole and amphotericin B, but 51.1% of the yeasts presented dose-dependent susceptibility (DDS) to nystatin. C. albicans showed a higher tendency to be nystatin resistant (52.8% DDS) than non-albicans species (44.4%). CONCLUSIONS: our data showed geographic differences among the species of yeasts isolated from the vagina and suggest that this fact has clinical relevance considering the differences in susceptibility, especially regarding nystatin, which could be important for the management of vulvovaginal candidiasis.

Magda Helena S. H., Ferrazza; Márcia L. Ferrarezi, Maluf; Marcia Edilaine Lopes, Consolaro; Cristiane Suemi, Shinobu; Terezinha Inez Estivalet, Svidzinski; Márcia Regina, Batista.

2005-02-01

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The effect of copaiba balsam on Walker 256 carcinoma inoculated into the vagina and uterine cervix of female rats / Efeito do óleo de copaíba no tumor de Walker 256 inoculado em vagina e colo de útero de ratas fêmeas  

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Full Text Available SciELO Brazil | Language: English Abstract in portuguese OBJETIVO: Verificar o efeito do óleo de copaíba da espécie Copaifera officinalis no carcinoma de Walker 256 inoculado em vagina e colo de útero de ratas. MÉTODOS: Foram utilizadas 18 ratas da linhagem Wistar, pesando entre 180-250g, distribuídas em dois grupos (CCop, GC). No 1º dia de experimento, e [...] m ambos os grupos foi inoculado 0,3ml de tumor de Walker 256 na concentração de 2x10(6); no 3º dia após essa inoculação, foi iniciada a administração de água destilada na dose de 4,8 ml/kg ao GC, e copaíba na dose de 4,8 ml/kg ao GCop. No 12º dia foi realizada a eutanásia das ratas e ressecado o tumor, sendo este pesado e averiguado seu volume. Os dados obtidos foram submetidos à análise estatística pelo método ANOVA. RESULTADOS: Observou-se que o óleo de copaíba apresentou um potencial inibitório negativo de 70%. CONCLUSÃO: O óleo de copaíba estimulou o crescimento tumoral. Abstract in english PURPOSE: To verify the copaiba balsam (Copaifera officinalis) effect on Walker 256 carcinoma inoculated into vagina and uterine cervix of rats. METHODS: Eighteen female Wistar rats weighing between 180-250g were used, distributed into 2 groups (GCop, GC). On the 1st day of the experiment, 0.3 ml of [...] Walker 256 carcinoma (2x10(6) concentration) was inoculated in both groups; on the 3rd day of the experiment, it was given 4.8 ml/kg of distilled water to the GC group, and 4.8 ml/kg of copaiba balsam to the GCop group. On the 12th day, euthanasia was performed and the tumor was grafted, being weighted and verified its volume. The data were submitted to statistical analysis with ANOVA test. RESULTS: It was observed that copaiba balsam presented a negative inhibitory potential of 70%. CONCLUSION: The copaiba balsam stimulated the tumor growth.

Nara Macedo Botelho, Brito; Marcus Vinicius Henriques, Brito; Rita de Kássia Vidigal, Carvalho; Lia Tavares de Moura Brasil, Matos; Rodolfo Costa, Lobato; Suelen Costa, Correa; Rosângela Baía, Brito.

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Denys-Drash syndrome, septated vagina and low level of anti-Mullerian hormone in male neonate  

Science.gov (United States)

There is a wide variety of genital abnormalities observed in patients with Denys-Drash syndrome (DDS). WT1 is thought to influence the genes related to genital development and mutations in this gene have been associated with DDS. DDS should be considered in the differential diagnosis of newborns with genital anomalies. In contrast to other conditions with 46,XY disorders of sex development, individuals with DDS often have duplicated genital organs (a double vagina, cervix or uterus). A double uterus has not yet been reported with 1390G>A (Arg464 Asn) mutation. However, duplicated genitals have been reported with other genetic mutations in patients with DDS. The duplicated genitals in DDS may be associated with low anti-Mullerian hormone (AMH) secretion. Measurement of the AMH levels may add to our understanding of variations in genital development and their abnormalities in disorders such as DDS. In conclusion, this is first case of low level of AMH and double uterus in 1390G>A (Arg464 Asn) mutations of DDS male. PMID:25077094

Lee, Hong Jun; Yeom, Jung-Sook; Park, Ji Sook; Park, Eun Sil; Seo, Ji-Hyun; Park, Chan-Hoo; Woo, Hyang-Ok; Youn, Hee-Shang

2014-01-01

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The Mayer-Rokitansky-K?ster-Hauser syndrome (congenital absence of uterus and vagina) - phenotypic manifestations and genetic approaches  

Science.gov (United States)

The Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome affects at least 1 out of 4500 women and has for a long time been considered as a sporadic anomaly. Congenital absence of upper vagina and uterus is the prime feature of the disease which, in addition, is often found associated with unilateral renal agenesis or adysplasia as well as skeletal malformations (MURCS association). The phenotypic manifestations of MRKH overlap various other syndromes or associations and thus require accurate delineation. Since MRKH manifests itself in males, the term GRES syndrome (Genital, Renal, Ear, Skeletal) might be more appropriate when applied to both sexes. The MRKH syndrome, when described in familial aggregates, seems to be transmitted as an autosomal dominant trait with an incomplete degree of penetrance and variable expressivity. This suggests the involvement of either mutations in a major developmental gene or a limited chromosomal deletion. Until recently progress in understanding the genetics of MRKH syndrome has been slow, however, now HOX genes have been shown to play key roles in body patterning and organogenesis, and in particular during genital tract development. Expression and/or function defects of one or several HOX genes may account for this syndrome. PMID:16441882

Guerrier, Daniel; Mouchel, Thomas; Pasquier, Laurent; Pellerin, Isabelle

2006-01-01

79

Genetic investigations of CFTR mutations in congenital absence of vas deferens, uterus, and vagina as a cause of infertility.  

Science.gov (United States)

A qualitative diagnosis of infertility requires attention to male and female physical abnormalities including endocrine anomalies and genetic conditions that interfere with reproduction. Many genes are likely to be involved in the complex process of reproduction. Congenital bilateral absence of the vas deferens (CBAVD) is a genital form of cystic fibrosis (CF) that is responsible for 2%-6% of male infertility. The incidence of CF varies in different populations; therefore, the incidence of CBAVD will also vary in different populations. The spectrum and distribution of cystic fibrosis transmembrane conductance regulator (CFTR) gene mutations differ between CBAVD and CF patients and are comparable to control individuals. Combinations of particular alleles at several polymorphic loci yield insufficient functional CFTR protein. CFTR mutations are also associated with congenital absence of the uterus and vagina (CAUV). Females with CF are found to be less fertile than normal healthy women. Because of techniques such as intracytoplasmic sperm injection (ICSI), CBAVD patients are now able to father children. Such couples, however, have an increased risk of having a child with cystic fibrosis, and therefore genetic testing and counseling should be provided. Around 10% of obstructive azoospermia is congenital and due to mutations in the CF gene. This review highlights the relationship of mutations in the CFTR gene with CBAVD and CAUV. PMID:18567645

Radpour, Ramin; Gourabi, Hamid; Dizaj, Ahmad Vosough; Holzgreve, Wolfgang; Zhong, Xiao Yan

2008-01-01

80

Characterisation of the bacterial microbiota of the vagina of dairy cows and isolation of pediocin-producing Pediococcus acidilactici  

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Full Text Available Abstract Background Uterine infections in dairy cows lower profitability of dairy operations. Infections of the reproductive tract are related to the overgrowth of pathogenic bacteria during the first three weeks after parturition. However, alterations in the vaginal microbiota composition in the first weeks after parturition remain poorly documented. Results In this study, bacteria isolated from the vagina of healthy pregnant, and infected postpartum cows were characterised by random amplification of polymorphic DNA (RAPD analysis and partial 16S ribosomal RNA (rDNA gene sequencing. Populations of bacilli and lactic acid bacteria of the genera Enterococcus, Lactobacillus, and Pediococcus were present in both healthy and infected cows. Infected cows had a significant increase in the vaginal enteric bacteria population which consisted mainly of Escherichia coli. Three E. coli isolates harboured the gene coding for Shiga-like-toxin (SLT I or II. Several isolates of the Pediococcus acidilactici were found to produce the bacteriocin pediocin AcH/PA-1. Quantitative PCR analyses of vaginal mucus samples collected from ten metritic cows before and after parturition confirmed the presence of the Lactobacillus group (Lactobacillus spp., Pediococcus spp., Leuconostoc spp., and Weissella spp.; Enterobacteriaceae, E. coli, and bacilli. The presence of the pediocin AcH/PA-1 structural gene and SLT genes were also confirmed with qPCR. Conclusions In conclusion, overgrowth of pathogenic bacteria, particularly E. coli, after parturition likely contributes to the development of metritis. Our microbiota analysis extends the information related to the composition of commensal bacteria in the bovine female reproductive tract and may facilitate the development of novel intervention strategies for prevention of uterine infections in dairy cows.

Wang Yvonne

2013-01-01

 
 
 
 
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Il Linguaggio della Vagina  

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Full Text Available La cultura delle masse è oggi una cultura prevalentemente visuale. Tra i segni visuali da tempo in crescita è quello, caratteristico, della depilazione pubica femminile. Originata all'interno della cultura porno come segno di passività, questa pratica si è incontrata con i simboli della pulizia, dell'igiene, del rispetto, trasformando così il proprio significato in quello di autonomia e libertà. Così le donne possono depilarsi per scopi erotici minimizzando però la valenza sessuale del gesto tramite la tendenza alla super-igiene.

Marco Menicocci

2011-12-01

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Il Linguaggio della Vagina  

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La cultura delle masse è oggi una cultura prevalentemente visuale. Tra i segni visuali da tempo in crescita è quello, caratteristico, della depilazione pubica femminile. Originata all'interno della cultura porno come segno di passività, questa pratica si è incontrata con i simboli della pulizia, dell'igiene, del rispetto, trasformando così il proprio significato in quello di autonomia e libertà. Così le donne possono depilarsi per scopi erotici minimizzando però la valenza sessuale de...

Marco Menicocci

2011-01-01

83

Rhabdomyosarcoma of the urinary bladder and vagina: a clinicopathologic study with emphasis on recurrent disease: a report from the Kiel Pediatric Tumor Registry and the German CWS Study.  

Science.gov (United States)

Rhabdomyosarcomas (RMS) of the urinary bladder and vagina vary in their biologic and clinical behavior and require different types of treatment. Anatomically the two organs are close, and the reason for these differences in behavior is unknown. We investigated tumor specimens of 51 urinary bladder RMS and 14 vaginal RMS with regard to histologic subtype, growth pattern, differentiation, and proliferation morphologically and immunohistochemically. Recurrences and/or "second look" specimens from 15 patients after chemotherapy were compared with the primary tumors. Within the 65 specimens we found 31 "classical" embryonal RMS, 26 embryonal RMS of botryoid subtype (BRMS), 3 embryonal RMS of spindle cell subtype, and 5 alveolar RMS. BRMS is more common in the vagina (11 BRMS of 14 cases) than in the urinary bladder RMS (15 BRMS of 54 cases). Classical embryonal RMS with a polypoid (exophytic) growth pattern is associated with a more favorable prognosis (92% 10-year survival) than the same type with a diffuse intramural (endophytic) growth pattern (68% 10-year survival, p = 0.02). The proliferation rate was associated with the degree of differentiation, but neither showed a correlation with prognosis. A marked maturation after chemotherapy was seen in the majority of recurrences and SL specimens, associated with lowered proliferation activity. Two of 12 patients with recurrences showing chemotherapy-induced maturation died of the disease. In conclusion, we determined that polypoid embryonal RMS of both the urinary bladder and the vagina have a comparably good prognosis. This includes all botryoid RMS. The poorer prognosis of the group of urinary bladder RMS as a whole was caused by a high incidence of diffusely growing RMS, which have a less favorable prognosis than polypoid RMS. Maturation after chemotherapy occurs frequently in RMS. In contrast to the excellent prognosis reported in other studies, we had two patients with fatal outcome despite chemotherapy-induced maturation in the recurrences. PMID:11420456

Leuschner, I; Harms, D; Mattke, A; Koscielniak, E; Treuner, J

2001-07-01

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Histopathologic Changes in the Uterus, Cervix and Vagina of Immature CD-1 Mice Exposed to Low Doses of Perfluorooctanoic Acid (PFOA) in a Uterotrophic Assay  

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The estrogenic and antiestrogenic potential of perfluorooctanoic acid (PFOA) was assessed using an immature mouse uterotrophic assay and by histologic evaluation of the uterus, cervix and vagina following treatment. Female offspring of CD-1 dams were weaned at 18 days old and assigned to groups of equal weight, and received 0, 0.01, 0.1, or 1 mg PFOA/kg BW/d by gavage with or without 17-? estradiol (E2, 500 ?g/kg/d) from PND18-20 (n=8/treatment/block). At 24 hr after the third dose (PND 21)...

Dixon, Darlene; Reed, Casey E.; Moore, Alicia B.; Gibbs-flournoy, Eugene A.; Hines, Erin P.; Wallace, Elizabeth A.; Stanko, Jason P.; Lu, Yi; Jefferson, Wendy N.; Newbold, Retha R.; Fenton, Suzanne E.

2012-01-01

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Normal tissue tolerance to external beam radiation therapy: The vagina; Dose de tolerance a l'irradiation des tissus sains: le vagin Normal  

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The vagina is a virtual cavity involved in sexual reproduction field. Due to its anatomical location, it may be exposed in whole or in part to ionizing radiation in external radiotherapy and/or brachytherapy of the pelvic region. This review aims to describe the vaginal acute and late side effects due to radiation, probably inadequately reported in the literature. Medline and PubMed literature searches were performed using the keywords -vaginal - radiotherapy - toxicity. The acute and late functional changes after external beam radiation consist mainly of drought. Their incidences are poorly described in the literature and the delivered doses even less. Recommendations are non-existent as the normal tissue complication probability (NTCP). Brachytherapy delivers high and heterogeneous doses, making it difficult to estimate the dose. The concomitant administration of chemotherapy appears to be a factor increasing the risk of toxicity. Modern techniques of conformal radiotherapy with modulated intensity appear to have little impact on this body. Only a maximum dose on each third of the vagina appears to be currently proposed to avoid the risk of side effects. (authors)

Magne, N. [Unite de curietherapie, departement de radiotherapie, institut de cancerologie de la Loire, 42 - Saint-Priest-en-Jarez (France); Chargari, C. [Service d' oncologie radiotherapie, hopital d' instruction des armees du Val-de-Grace, 75 - Paris (France); Pointreau, Y. [Clinique d' oncologie radiotherapie, centre Henry-S.-Kaplan, hopital de Bretonneau, CHU de Tours, 37 - Tours (France); Haie-Meder, C. [Service de curietherapie, departement de radiotherapie, institut Gustave-Roussy, 94 - Villejuif (France)

2010-07-15

86

[Cytological and bacteriological examinations of the cervix and vagina. A review of the results obtained in a laboratory for analyses in Guadeloupe (author's transl)].  

Science.gov (United States)

The authors give the results of their cytological and bacteriological examinations of the cervix and vagina carried out routinely in a laboratory. They emphasize, in detailing their method of working, the criteria that they feel must be adopted in an attempt to code the qualitative appraisal of direct examination and the result of studying the cultures. The first part of the paper deals with an overall survey of the 4,573 examinations which were carried out over a period of 8 years. The second part is concerned with a more detailed analysis of the 883 samples which were divided into 4 categories: pregnant women, those having oral contraception, those with an intra-uterine device, and others. There are several variations revealed between these 4 categories as far as the white cell count, the bacterial flora and even pathogenic organisms are concerned. PMID:7334191

Millan, J; Crenn, O; Lidome, E

1981-01-01

87

Effects of depomedroxyprogesterone acetate on the development and maintenance of Candida albicans in the vagina of oophorectomized Wistar rats (Rattus norvegicus)  

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Full Text Available SciELO Brazil | Language: English Abstract in portuguese O objetivo do presente estudo foi determinar os efeitos do acetato de depomedroxyprogesterona (ADMP) no desenvolvimento e manutenção de Candida albicans na vagina de ratas Wistar ooferectomizadas. Os animais foram divididos em grupos controle negativos (GCN), que receberam injeções de salina estéril [...] ; grupos controle positivos (GCP), que receberam injeções de valerato de estradiol; e grupos progesterona (GP), nos quais foram feitas injeções de Depo-Provera®. Após uma semana da aplicação hormonal, foi induzida a infecção vaginal por C. albicans em todos os grupos, detectada por cultura para leveduras vaginais e esfregaço de Papanicolaou. Foram feitas ainda imagens por microscopia eletrônica de varredura e transmissão para confirmar a infecção pela levedura no GP. Foram observados diferentes níveis de progesterona em GP, entre os valores basais e após a indução hormonal (P Abstract in english The objective of this study was to determine the effect of medroxyprogesterone acetate (DMPA) on the development and maintenance of Candida albicans in the vagina of oophorectomized Wistar rats. The animals were divided into negative control groups (NCG), which received injections of sterile saline; [...] positive control groups (PCG), which were given injections of estradiol valerate; and progesterone groups (PG), which were given injections of Depo-Provera®. After one week of hormonal induction, vaginal infection by C. albicans was induced in all the groups and detected by vaginal yeast culture and Papanicolaou smear. In addition, scanning and transmission electron microscopy images were obtained to confirm the vaginal infection by yeast in PG. A difference in progesterone levels in PG was observed between the basal level and after hormonal induction (P

Agenor, Storti-Filho; Edilson, Damke; Márcia Aparecida, Carrara; Marcia Regina, Batista; Lucélia, Donatti; Cinthia Gandolfi, Boer; Terezinha Inez Estivalet, Svizdinski; Márcia Edilaine Lopes, Consolaro.

2011-03-01

88

Effects of depomedroxyprogesterone acetate on the development and maintenance of Candida albicans in the vagina of oophorectomized Wistar rats (Rattus norvegicus)  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in portuguese O objetivo do presente estudo foi determinar os efeitos do acetato de depomedroxyprogesterona (ADMP) no desenvolvimento e manutenção de Candida albicans na vagina de ratas Wistar ooferectomizadas. Os animais foram divididos em grupos controle negativos (GCN), que receberam injeções de salina estéril [...] ; grupos controle positivos (GCP), que receberam injeções de valerato de estradiol; e grupos progesterona (GP), nos quais foram feitas injeções de Depo-Provera®. Após uma semana da aplicação hormonal, foi induzida a infecção vaginal por C. albicans em todos os grupos, detectada por cultura para leveduras vaginais e esfregaço de Papanicolaou. Foram feitas ainda imagens por microscopia eletrônica de varredura e transmissão para confirmar a infecção pela levedura no GP. Foram observados diferentes níveis de progesterona em GP, entre os valores basais e após a indução hormonal (P Abstract in english The objective of this study was to determine the effect of medroxyprogesterone acetate (DMPA) on the development and maintenance of Candida albicans in the vagina of oophorectomized Wistar rats. The animals were divided into negative control groups (NCG), which received injections of sterile saline; [...] positive control groups (PCG), which were given injections of estradiol valerate; and progesterone groups (PG), which were given injections of Depo-Provera®. After one week of hormonal induction, vaginal infection by C. albicans was induced in all the groups and detected by vaginal yeast culture and Papanicolaou smear. In addition, scanning and transmission electron microscopy images were obtained to confirm the vaginal infection by yeast in PG. A difference in progesterone levels in PG was observed between the basal level and after hormonal induction (P

Agenor, Storti-Filho; Edilson, Damke; Márcia Aparecida, Carrara; Marcia Regina, Batista; Lucélia, Donatti; Cinthia Gandolfi, Boer; Terezinha Inez Estivalet, Svizdinski; Márcia Edilaine Lopes, Consolaro.

89

Histometric Parameters of Uterus and Vagina in Breeder Female Rabbits on the Day After Weaning According to the Ordinal Number of Parturitions / Parámetros Histométricos en Útero y Vagina de Conejas Reproductoras en el día Posterior al Destete Según el Número Ordinal de Partos  

Scientific Electronic Library Online (English)

Full Text Available SciELO Chile | Language: English Abstract in spanish El objetivo del presente estudio fue determinar en conejas Nueva Zelanda el efecto del número ordinal de partos sobre algunos parámetros histológicos, en el día posterior al destete. A partir de hembras de primero, segundo y tercer parto se obtuvieron fragmentos de tejido uterino y vaginal los que s [...] e procesaron mediante la técnica de inclusión en parafina para efectuar cortes histológicos. En ocho campos microscópicos capturados con una cámara conectada a un microscopio óptico se midió la altura del epitelio luminal y glandular del endometrio; el grosor del epitelio de la vagina y del miometrio. A partir de los resultados obtenidos se concluye que existen diferencias significativas (p Abstract in english The objective of this study was to establish in New Zealand female rabbits, the effect of ordinal number of parturitions on some histological parameters on the day after weaning. Tissue fragments of uterus and vagina were obtained from females of first, second and third parturitions and were process [...] ed imbedding them in paraffin in order to do histological cuts. In eight microscope fields captured by a camera connected to an optic microscope, the lumen and glandular endometrial epithelium height, as well as the thickness of vaginal and myometrium epithelium thickness were measured. From the results that were obtained it was concluded that there are significant differences (p

José Alfonso, Banda-Herrera; Jesús, Aragón Hernández; Reyes, López Ordaz; Jorge, Hernández Espinosa; Mario, Pérez-Martínez.

2014-06-01

90

Histometric Parameters of Uterus and Vagina in Breeder Female Rabbits on the Day After Weaning According to the Ordinal Number of Parturitions / Parámetros Histométricos en Útero y Vagina de Conejas Reproductoras en el día Posterior al Destete Según el Número Ordinal de Partos  

Scientific Electronic Library Online (English)

Full Text Available SciELO Chile | Language: English Abstract in spanish El objetivo del presente estudio fue determinar en conejas Nueva Zelanda el efecto del número ordinal de partos sobre algunos parámetros histológicos, en el día posterior al destete. A partir de hembras de primero, segundo y tercer parto se obtuvieron fragmentos de tejido uterino y vaginal los que s [...] e procesaron mediante la técnica de inclusión en parafina para efectuar cortes histológicos. En ocho campos microscópicos capturados con una cámara conectada a un microscopio óptico se midió la altura del epitelio luminal y glandular del endometrio; el grosor del epitelio de la vagina y del miometrio. A partir de los resultados obtenidos se concluye que existen diferencias significativas (p Abstract in english The objective of this study was to establish in New Zealand female rabbits, the effect of ordinal number of parturitions on some histological parameters on the day after weaning. Tissue fragments of uterus and vagina were obtained from females of first, second and third parturitions and were process [...] ed imbedding them in paraffin in order to do histological cuts. In eight microscope fields captured by a camera connected to an optic microscope, the lumen and glandular endometrial epithelium height, as well as the thickness of vaginal and myometrium epithelium thickness were measured. From the results that were obtained it was concluded that there are significant differences (p

José Alfonso, Banda-Herrera; Jesús, Aragón Hernández; Reyes, López Ordaz; Jorge, Hernández Espinosa; Mario, Pérez-Martínez.

91

Effects of depomedroxyprogesterone acetate on the development and maintenance of Candida albicans in the vagina of oophorectomized Wistar rats (Rattus norvegicus  

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Full Text Available The objective of this study was to determine the effect of medroxyprogesterone acetate (DMPA on the development and maintenance of Candida albicans in the vagina of oophorectomized Wistar rats. The animals were divided into negative control groups (NCG, which received injections of sterile saline; positive control groups (PCG, which were given injections of estradiol valerate; and progesterone groups (PG, which were given injections of Depo-Provera®. After one week of hormonal induction, vaginal infection by C. albicans was induced in all the groups and detected by vaginal yeast culture and Papanicolaou smear. In addition, scanning and transmission electron microscopy images were obtained to confirm the vaginal infection by yeast in PG. A difference in progesterone levels in PG was observed between the basal level and after hormonal induction (PO objetivo do presente estudo foi determinar os efeitos do acetato de depomedroxyprogesterona (ADMP no desenvolvimento e manutenção de Candida albicans na vagina de ratas Wistar ooferectomizadas. Os animais foram divididos em grupos controle negativos (GCN, que receberam injeções de salina estéril; grupos controle positivos (GCP, que receberam injeções de valerato de estradiol; e grupos progesterona (GP, nos quais foram feitas injeções de Depo-Provera®. Após uma semana da aplicação hormonal, foi induzida a infecção vaginal por C. albicans em todos os grupos, detectada por cultura para leveduras vaginais e esfregaço de Papanicolaou. Foram feitas ainda imagens por microscopia eletrônica de varredura e transmissão para confirmar a infecção pela levedura no GP. Foram observados diferentes níveis de progesterona em GP, entre os valores basais e após a indução hormonal (P<0,0001. Neste grupo, 100,0% das ratas contraíram a infecção vaginal na primeira semana, mas não a mantiveram até a terceira semana. A forma farmacêutica de ADMP foi efetiva em induzir as fases de metaestro e diestro do ciclo estral das ratas, da mesma forma que usando progesterona pura. Em contraste com o que ocorre no tratamento com estrógeno, a progesterona não pôde manter a infecção vaginal experimental por C. albicans por um período significativo de tempo.

Agenor Storti-Filho

2011-03-01

92

Use of internal artificial vaginas for breeding soundness evaluation in range bulls: an alternative for electroejaculation allowing observation of sex drive and mating ability.  

Science.gov (United States)

The objective of this study was to test the efficacy of an inexpensive, reusable internal artificial vagina (IAV) developed for breeding soundness evaluation of range beef bulls. In addition, sexual behavior during semen collection by IAV was compared to behavior during pasture breeding. Breeding soundness exams (BSEs) were conducted on 165 bulls in two consecutive years (96 in Year 1 and 69 in Year 2). In Year 1, BSEs were done twice in all bulls, once by a conventional protocol using electroejaculation (EEJ), followed by the IAV method, one week later. In Year 2, all BSEs were done on one day; 69 bulls by the IAV method followed by EEJ in 21 bulls that failed to serve the IAV. For semen collection using an IAV, mount cows were restrained in breeding crates and an IAV was inserted into the vagina just beyond the depth of the vestibular sphincter. After each copulation, the IAV was replaced for the next bull to be tested. Semen collection by IAV was successful for all bulls that mounted and penetrated cows during the testing period (54.3 and 69.6% of the bulls served the cows with IAVs in Year 1 and 2, respectively). Semen was collected successfully by EEJ from all bulls in both years. Differences were observed between semen collection methods in semen volume and percentage of sperm staining alive; however, the differences were opposite in Year 1 and 2 and, therefore, were probably due to natural variations in time and within bull rather than the method of semen collection. Semen collection by IAV allowed the detection of problems that prevented copulation in 8 bulls (4.8%) that were determined to be satisfactory potential breeders when semen was collected by EEJ. In Year 1, breeding observations were made at pasture for 15 bulls that served, and 15 bulls that did not serve cows with an IAV. Bulls that did not serve the IAV during the test period had fewer mounts, attempts to mount, and completed services at pasture than bulls that had served the IAV, indicating that such bulls are likely to be less efficient breeders. In conclusion, IAVs might be used as an alternative to EEJ for breeding soundness evaluation in about 50-70% of range bulls. Semen collection by IAV also allows observation of sex drive and mating ability thus improves the ability to select sound breeding bulls. PMID:15302374

Barth, Albert D; Arteaga, Andres A; Brito, Leonardo F C; Palmer, Colin W

2004-09-01

93

Lymphoepithelioma-like carcinoma of the vagina: a case report with special reference to the immunophenotype of the tumor cells and tumor-infiltrating lymphoreticular cells.  

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Lymphoepithelial carcinoma (Schmincke's tumor) is a relatively common malignancy in the upper respiratory tract (nasopharynx), but it rarely occurs at other sites. We describe here the first case of a vaginal neoplasm that closely resembled lymphoepithelial carcinoma in its histological features and immunophenotype. The tumor was detected in an 81-year-old woman who presented with recurrent vaginal bleeding. On colposcopy, an ulcerated polypoid tumor mass was seen in the posterior wall of the middle portion of the vagina. Histologic examination revealed an undifferentiated spindle-cell carcinoma (KL1+, chromogranin A-, vimentin-) with abundant lymphocytes (mostly UCHL1+ T cells), plasma cells, and macrophages (CD68+) in and around the tumor cell nests. A minority of the tumor cells exhibited overexpression of p53 protein and a quarter of the tumor cells reacted with the antibody MIB1, that is, were in a proliferate state. The tumor cells did not react with the monoclonal antibody DAKO-EBV, which detects a latent membrane protein (LMP-1) encoded by the Epstein-Barr virus. The tumor underwent regression after radiotherapy. No signs of recurrence or dissemination of the carcinoma have been detected clinically during the 6 months since treatment. PMID:8005741

Dietl, J; Horny, H P; Kaiserling, E

1994-04-01

94

Pemphigus vulgaris of the vagina--its cytomorphologic features on liquid-based cytology and pitfalls: case report and cytological differential diagnosis.  

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Pemphigus vulgaris is an autoimmune bullous disease that involves skin and mucous membrane. Although the female genital tract is rarely affected, its cytomorphologic features on a conventional cervicovaginal smear have been notoriously described with a possibility of being misdiagnosed as neoplastic lesions. Its cytological mimicry for squamous cell carcinoma has been described as having serious misdiagnostic potential, particularly if appropriate clinical information is not provided. We report a case of pemphigus vulgaris involving the vagina diagnosed on a liquid-based cervicovaginal smear Thin Prep(R) (TP). The smear was initially reported as squamous cell carcinoma. However, re-evaluation of the TP smear raised the suspicion of pemphigus, which was supported subsequently by clinical information and tissue biopsy confirmation. We described the cytologic features of pemphigus vulgaris on a TP smear and compared them with those of neoplastic conditions. Pemphigus cells on a TP smear exhibit similar cytomorphologic features to those on a conventional smear. Recognizing euchromatin pattern and smooth nuclear contours which may be better appreciated on a TP can prevent overdiagnosis. PMID:19526581

Onuma, Kazuya; Kanbour-Shakir, Amal; Modery, Judith; Kanbour, Anisa

2009-11-01

95

Detection of hydrogen peroxide-producing Lactobacillus species in the vagina: a comparison of culture and quantitative PCR among HIV-1 seropositive women  

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Full Text Available Abstract Background The presence of hydrogen peroxide (H2O2 producing Lactobacillus in the vagina may play a role in controlling genital HIV-1 shedding. Sensitive molecular methods improve our ability to characterize the vaginal microbiota; however, they cannot characterize phenotype. We assessed the concordance of H2O2-producing Lactobacillus detected by culture with quantitative PCR (qPCR detection of Lactobacillus species commonly assumed to be H2O2-producers. Methods Samples were collected as part of a prospective cohort study of HIV-1 seropositive US women. Cervicovaginal lavage specimens were tested for L. crispatus and L. jensenii using 16S rRNA gene qPCR assays. Vaginal swabs were cultured for Lactobacillus and tested for H2O2-production. We calculated a kappa statistic to assess concordance between culture and qPCR. Results Culture and qPCR results were available for 376 visits from 57 women. Lactobacilli were detected by culture at 308 (82% visits, of which 233 of 308 (76% produced H2O2. L. crispatus and/or L. jensenii were detected at 215 (57% visits. Concordance between detection of L. crispatus and/or L. jensenii by qPCR and H2O2-producing Lactobacillus by culture was 75% (kappa = 0.45. Conclusions Among HIV-1 seropositive women, there was a moderate level of concordance between H2O2-producing Lactobacillus detected by culture and the presence of L. crispatus and/or L. jensenii by qPCR. However, one-quarter of samples with growth of H2O2-producing lactobacilli did not have L. crispatus or L. jensenii detected by qPCR. This discordance may be due to the presence of other H2O2-producing Lactobacillus species.

Balkus Jennifer E

2012-08-01

96

Citologia Hormonal do Trato Urinário Baixo e da Vagina de Mulheres na Pós-menopausa, antes e durante Estrogenioterapia Oral e Transdérmica / Urinary and Vaginal Cytology of Postmenopausal Women with Oral and Transdermal Estrogen Replacement  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese Objetivo: avaliar a ação dos estrogênios por via oral ou transdérmica nas células do trato urinário baixo e da vagina, em mulheres menopausadas. Métodos: foram incluídas 25 mulheres na pós-menopausa, nas quais se estudaram os efeitos citológicos da terapia de reposição hormonal estrogênica, por via [...] oral e por via transdérmica, sobre as células da vagina e do sedimento urinário. As pacientes foram distribuídas aleatoriamente em 2 grupos: Grupo I, constituído por 14 mulheres que receberam 0,625 mg de estrogênio conjugado eqüino associado a 5 mg de acetato de medroxiprogesterona, por via oral, diariamente sem intervalo por três meses, e Grupo II, formado por 11 mulheres que fizeram uso de 17-beta-estradiol matricial na dose de 50 mig, por via transdérmica, semanalmente, associado a 5 mg de acetato de medroxiprogesterona diariamente por três meses. As amostras urinárias foram obtidas do jato inicial da primeira urina da manhã, após asseio dos genitais, em frascos estéreis fornecidos pelo laboratório. A urina foi centrifugada e o esfregaço realizado a partir do sedimento urinário. Os esfregaços da vagina e do sedimento urinário foram imediatamente fixados em álcool absoluto e corados pelo método de Shorr. Resultados: observou-se que nas pacientes que utilizaram a via oral, houve maturação das células da vagina (o índice se elevou de 45,4 a 65,5 com dois meses de tratamento, permanecendo praticamente constante (62,0) a seguir. Quanto às células urinárias, não houve variação do valor de maturação (56,4 antes da medicação e 60,4 no final do período). Ao examinarmos tanto as células da urina quanto da vagina de pacientes que utilizaram a via transdérmica, notou-se que houve resposta satisfatória. Conclusão: com estes resultados podemos sugerir que os estrogênios, quando administrados por via transdérmica, estão associados à resposta satisfatória quanto ao trofismo tanto na vagina quanto na uretra. No entanto, quando se utiliza a via oral, nem sempre este resultado pode ser observado. Abstract in english Objective: to study the effects of oral or transdermal estrogen replacement on the lower urinary tract and vagina in postmenopausal women. Methods: we studied 25 postmenopausal women evaluating the oral or transdermic estrogen replacement effects on the vaginal cells and urinary sediment during 3 mo [...] nths. The patients were randomly distributed into 2 groups: Group I, n = 14, treated orally with 0.625 mg equine conjugated estrogen plus 5 mg medroxyprogesterone acetate, daily for 3 months; Group II, n = 11, treated transdermally with 50 mug 17-ß-estradiol, once a week, plus 5 mg medroxyprogesterone. Daily, for 3 months, urinary samples were collected from the first miction in the morning after urogenital antisepsis into sterile tubes. The sample was centrifuged and the sediment was smeared. Vaginal and urinary smears were then fixed in absoluted alcohol and stained by the method of Shorr. Results: the patients who used the oral route presented maturation of the vaginal cells (from 45.4 to 65.5% after 2 months of treatment, maintaing 62% afterwards) but this did not occur with urinary cells (56.4 before treatment versus 60.4% at the end of the period). The transdermal route promoted maturation of vaginal and urinary cells. Conclusion: we have concluded that transdermal estrogens have satisfactory effects both on vaginal and urethral sites. However, with the oral route we did not find the expected results in the urinary tract in all cases.

Áurea Belas, Lustosa; Manoel João Batista Castello, Girão; Marair Gracio Ferreira, Sartori; Edmund Chada, Baracat; Geraldo Rodrigues de, Lima.

97

Citologia Hormonal do Trato Urinário Baixo e da Vagina de Mulheres na Pós-menopausa, antes e durante Estrogenioterapia Oral e Transdérmica Urinary and Vaginal Cytology of Postmenopausal Women with Oral and Transdermal Estrogen Replacement  

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Full Text Available Objetivo: avaliar a ação dos estrogênios por via oral ou transdérmica nas células do trato urinário baixo e da vagina, em mulheres menopausadas. Métodos: foram incluídas 25 mulheres na pós-menopausa, nas quais se estudaram os efeitos citológicos da terapia de reposição hormonal estrogênica, por via oral e por via transdérmica, sobre as células da vagina e do sedimento urinário. As pacientes foram distribuídas aleatoriamente em 2 grupos: Grupo I, constituído por 14 mulheres que receberam 0,625 mg de estrogênio conjugado eqüino associado a 5 mg de acetato de medroxiprogesterona, por via oral, diariamente sem intervalo por três meses, e Grupo II, formado por 11 mulheres que fizeram uso de 17-beta-estradiol matricial na dose de 50 mig, por via transdérmica, semanalmente, associado a 5 mg de acetato de medroxiprogesterona diariamente por três meses. As amostras urinárias foram obtidas do jato inicial da primeira urina da manhã, após asseio dos genitais, em frascos estéreis fornecidos pelo laboratório. A urina foi centrifugada e o esfregaço realizado a partir do sedimento urinário. Os esfregaços da vagina e do sedimento urinário foram imediatamente fixados em álcool absoluto e corados pelo método de Shorr. Resultados: observou-se que nas pacientes que utilizaram a via oral, houve maturação das células da vagina (o índice se elevou de 45,4 a 65,5 com dois meses de tratamento, permanecendo praticamente constante (62,0 a seguir. Quanto às células urinárias, não houve variação do valor de maturação (56,4 antes da medicação e 60,4 no final do período. Ao examinarmos tanto as células da urina quanto da vagina de pacientes que utilizaram a via transdérmica, notou-se que houve resposta satisfatória. Conclusão: com estes resultados podemos sugerir que os estrogênios, quando administrados por via transdérmica, estão associados à resposta satisfatória quanto ao trofismo tanto na vagina quanto na uretra. No entanto, quando se utiliza a via oral, nem sempre este resultado pode ser observado.Objective: to study the effects of oral or transdermal estrogen replacement on the lower urinary tract and vagina in postmenopausal women. Methods: we studied 25 postmenopausal women evaluating the oral or transdermic estrogen replacement effects on the vaginal cells and urinary sediment during 3 months. The patients were randomly distributed into 2 groups: Group I, n = 14, treated orally with 0.625 mg equine conjugated estrogen plus 5 mg medroxyprogesterone acetate, daily for 3 months; Group II, n = 11, treated transdermally with 50 mug 17-ß-estradiol, once a week, plus 5 mg medroxyprogesterone. Daily, for 3 months, urinary samples were collected from the first miction in the morning after urogenital antisepsis into sterile tubes. The sample was centrifuged and the sediment was smeared. Vaginal and urinary smears were then fixed in absoluted alcohol and stained by the method of Shorr. Results: the patients who used the oral route presented maturation of the vaginal cells (from 45.4 to 65.5% after 2 months of treatment, maintaing 62% afterwards but this did not occur with urinary cells (56.4 before treatment versus 60.4% at the end of the period. The transdermal route promoted maturation of vaginal and urinary cells. Conclusion: we have concluded that transdermal estrogens have satisfactory effects both on vaginal and urethral sites. However, with the oral route we did not find the expected results in the urinary tract in all cases.

Áurea Belas Lustosa

2002-10-01

98

Citología y Análisis Morfométrico de las Células del Epitelio Vaginal Durante el Ciclo Estral en Ovejas de Pelo (Ovis aries) / Citology and Morphometric Analysis of Epithelial Cells from the Vagina of Hair Sheep Ewes (Ovis aries) During their Estrous Cycle  

Scientific Electronic Library Online (English)

Full Text Available SciELO Chile | Language: Spanish Abstract in spanish La citología vaginal puede usarse para caracterizar estados del ciclo reproductivo de la hembra. Sin embargo, no ha sido validada en ovinos de pelo, y ofrece resultados inexactos debido a interpretaciones subjetivas. El objetivo del presente trabajo es tipificar las características morfológicas y mo [...] rfométricas de las células epiteliales de la vagina durante el ciclo estral en ovinos de pelo. Cinco borregas Santa Cruz se sincronizaron con esponjas intravaginales. Desde el día del 1er celo posterior al retiro de la esponja y hasta el siguiente celo, se obtuvieron muestras diarias del epitelio vaginal de cada oveja, y se cuantificó el número de células parabasales, intermedias y superficiales, y se midió la longitud, perímetro y área de citoplasma y núcleo de cada una. Los resultados muestran que las células superficiales incrementan (P Abstract in english Vaginal cytology can be used to characterize stages of the reproductive cycle of the female. However, it has not been validated in hair sheep, and generates inaccurate results due to subjective interpretations. Thus, the purpose of the present work is to typify morphologic and morphometric character [...] istics of the epithelial cells from the vagina during the estrous cycle of hair sheep. Five Saint Croix ewes were synchronized with intravaginal sponges. Day zero of the cycle was considered the day of first estrus after sponge withdrawal. From this day until next estrus, samples from the vaginal epithelium were obtained daily from each ewe. The number of basal, intermediate and superficial cells was quantified, and length, perimeter, and area from cytoplasm and nucleus were obtained. The results show that the number of superficial cells increase (P

Neftali, Clemente Ovando; Agustín, Orihuela Trujillo; Fernando Iván, Flores Pérez; Virginio, Aguirre Flores.

99

Citología y Análisis Morfométrico de las Células del Epitelio Vaginal Durante el Ciclo Estral en Ovejas de Pelo (Ovis aries) / Citology and Morphometric Analysis of Epithelial Cells from the Vagina of Hair Sheep Ewes (Ovis aries) During their Estrous Cycle  

Scientific Electronic Library Online (English)

Full Text Available SciELO Chile | Language: Spanish Abstract in spanish La citología vaginal puede usarse para caracterizar estados del ciclo reproductivo de la hembra. Sin embargo, no ha sido validada en ovinos de pelo, y ofrece resultados inexactos debido a interpretaciones subjetivas. El objetivo del presente trabajo es tipificar las características morfológicas y mo [...] rfométricas de las células epiteliales de la vagina durante el ciclo estral en ovinos de pelo. Cinco borregas Santa Cruz se sincronizaron con esponjas intravaginales. Desde el día del 1er celo posterior al retiro de la esponja y hasta el siguiente celo, se obtuvieron muestras diarias del epitelio vaginal de cada oveja, y se cuantificó el número de células parabasales, intermedias y superficiales, y se midió la longitud, perímetro y área de citoplasma y núcleo de cada una. Los resultados muestran que las células superficiales incrementan (P Abstract in english Vaginal cytology can be used to characterize stages of the reproductive cycle of the female. However, it has not been validated in hair sheep, and generates inaccurate results due to subjective interpretations. Thus, the purpose of the present work is to typify morphologic and morphometric character [...] istics of the epithelial cells from the vagina during the estrous cycle of hair sheep. Five Saint Croix ewes were synchronized with intravaginal sponges. Day zero of the cycle was considered the day of first estrus after sponge withdrawal. From this day until next estrus, samples from the vaginal epithelium were obtained daily from each ewe. The number of basal, intermediate and superficial cells was quantified, and length, perimeter, and area from cytoplasm and nucleus were obtained. The results show that the number of superficial cells increase (P

Neftali, Clemente Ovando; Agustín, Orihuela Trujillo; Fernando Iván, Flores Pérez; Virginio, Aguirre Flores.

2013-09-01

100

Primary invasive squamous carcinoma of the vagina  

International Nuclear Information System (INIS)

Forty-three cases of primary vaginal squamous cell cancer were treated at the University of Wisconsin Hospital between 1956 and 1971. These cases comprised of 1.2% of patients admitted to the University Hospital with female genital tract cancer. Evidence is presented to support a modification of the currently accepted FIGO staging system for vaginal carcinoma (Stage II disease). Radiation therapy using both external beam and brachyradium equivalents or interstitial implantation of suitable isotopes was an effective method for the treatment of patients having early and locally advanced invasive vaginal cancer. The 5-year absolute survival rate for the entire series was 37.2%. Absolute survival rate by modified FIGO clinical staging was 66% for Stages I and IIA, 31% for Stage IIB, 25% for Stage III, and 0% for Stage IV

 
 
 
 
101

Presencia de malla de prolene en vagina / The presence of a Prolene mesh in the vagina  

Scientific Electronic Library Online (English)

Full Text Available SciELO Spain | Language: Spanish Abstract in spanish Objetivo: Describir un caso clínico de una paciente en la que tras la colocación de malla de Prolene® como refuerzo en la corrección de cistocele recidivado, presenta complicaciones. Método/resultado: Paciente mujer de 75 años de edad con antecedentes de corrección de cistocele con malla de prolene [...] presenta incontinencia de orina y erosión vaginal por la propia malla. Conclusiones: El uso de malla para la corrección de cistocele tiene la ventaja de aportar mayor soporte a la colporrafia y evitar la recidiva del cistocele, aunque puede presentar complicaciones como en nuestro caso clínico de migración de la malla, aparición de fístula, infección o intolerancia. Abstract in english Objective: To describe the clinical case of a patient presenting complications after the implantation of a Prolene mesh as reinforcement for the correction of a recurrent cystocele. Methods/results: Seventy-five-years-old female patient with history of previous cystocele repair with Prolene mesh pre [...] senting urinary incontinence and vaginal erosion of the mesh. Conclusions: The use of mesh for the repair of cystoceles has the advantage of providing greater support to the colporrhaphy and avoiding recurrences. Nevertheless, it may present complications as in our reported case with mesh migration, fistula, infection, or intolerance.

Anna, Bujons; Carlos, Errando; Manel, Prados; Carlos, Báez; Pedro, Arañó; Humberto, Villavicencio.

102

Uterus and vagina. TNM classification of malignant tumours  

International Nuclear Information System (INIS)

Cervix uteri and Corpus uteri were amongst the first sites to be classified by the TNM system. The ''League of Nations'' Stages for carcinoma of the cervix have been used with minor modifications for nearly fifty years and because these are accepted by the Federation Internationale de Gynecologie et d'Obstetrique (FIGO), the TNM categories have been defined to correspond to the FIGO stages. Some amendments have been made in collaboration with FIGO and the classifications now published will remain unchanged until at least 1986

103

Pregnancy Complications: Bleeding and Spotting from the Vagina  

Science.gov (United States)

... The gallbladder stores and releases bile, a substance produced in the liver. Bile helps digest fat. When bile sits in the gallbladder for too long, hard, solid nuggets called gallstones can form. The stones can ...

104

Arcanobacterium hippocoleae sp. nov., from the vagina of a horse.  

Science.gov (United States)

A polyphasic taxonomic study was performed on a previously unidentified gram-positive, facultatively anaerobic, diphtheroid-shaped organism isolated from a vaginal discharge of a horse. Comparative 16S rRNA gene sequencing demonstrated that the strain was a member of the genus Arcanobacterium, but sequence divergence values of >4% with described species of this genus (viz: Arcanobacterium haemolyticum, Arcanobacterium bernardiae, Arcanobacterium phocae, Arcanobacterium pluranimalium and Arcanobacterium pyogenes) demonstrated that the isolate represented a novel species. The unknown bacterium was readily distinguished from other Arcanobacterium species by biochemical tests. Based on phylogenetic and phenotypic evidence, it is proposed that the unknown bacterium be classified as Arcanobacterium hippocoleae sp. nov. The type strain of A. hippocoleae is CCUG 44697T (= CIP 106850T). PMID:11931175

Hoyles, Lesley; Falsen, Enevold; Foster, Geoffrey; Rogerson, Forbes; Collins, Matthew D

2002-03-01

105

Late relapse of embryonal rhabdomyosarcoma, botryoid variant, of the vagina.  

Science.gov (United States)

We report on two very similar cases of vaginal embryonal RMS, botryoid variant, that relapsed 9 and 10 years after initial diagnosis, a few months after the menarche in both cases. A possible causal association with estrogen hormones is hypothesized, particularly for the second case described, in which estrogen receptors were negative in the primary tumor specimen and positive in the relapsing tumor specimen. PMID:18253956

Vasquez, Roberto; Collini, Paola; Meazza, Cristina; Favini, Francesca; Casanova, Michela; Ferrari, Andrea

2008-07-01

106

Botryoid rhabdomyosarcoma of vagina--two case reports.  

Science.gov (United States)

Botryoid rhabdomyosarcoma, previously considered a type of embryonal rhabdomyosarcoma, has clinicopathological features distinctive enough to warrant its classification as a separate entity. It almost always occurs in children under 5 years of age. Two cases of botryoid rhabdomyosarcoma are reported here because of their relative rarity. PMID:15887839

Kar, Tushar; Dash, Asaranti; Kanungo, Shyama; Kar, Ashok

2004-09-01

107

Malla de polipropileno multifilamento con autofijación de silicona exteriorizada a vagina / Multifilament polypropylene mesh with exteriorization of the silicone anchorage to the vagina  

Scientific Electronic Library Online (English)

Full Text Available SciELO Spain | Language: Spanish Abstract in spanish Objetivo: Describir un caso de falla de en una cirugía de cinta suburetral para corrección de la incontinencia de orina de esfuerzo con sistema Safyre VS (vaginal-suprapubic approach) multifilamento, a los 34 meses de buena evolución. Método: Descripción del caso y su resolución. Resultado: Se prese [...] ntó con descenso del sistema de sujeción lateral y erosión de la mucosa vaginal con exposición de la cinta e infección. Se retiró con gran facilidad el sistema de anclaje de silicona que se encontraba suelto y se colocó una nueva cinta suburetral con sistema TVT-O, recuperando la continencia antes lograda. Conclusiones: La malla sintéticas de los sistemas de corrección con cinta suburetral para la incontinencia de orina de esfuerzo, deben ser de polipropileno, macroporo y monofilamento. Estas características permiten una mejor biointegración, reduciendo teóricamente el número de complicaciones (erosión de pared vaginal, exposición y sobreinfección). Respecto a la falla del sistema de sujeción de silicona, ya que no se han informado otros casos en los estudios de seguimiento entre 12 y 36 meses (media 14 y 18 meses), sólo los estudios que contemplen seguimientos a largo plazo permitirán decir si se trata de un caso aislado o aparecerán otros. Abstract in english Objectives: To describe the failure of one case of suburethral tape for the correction of the stress urinary incontinence with the multifilament Sapphire VS (vaginal-suprapubic approach) system after 34 months of good outcome. Methods: Description of the case and its resolution. Results: The patient [...] presented with a descent of the lateral fixation and erosion of the vaginal mucosa with exposure of the mesh and infection. The silicone fixation system, which was loose, was retrieved very easily and a new suburethral mesh with the system TVT-O was inserted; the patient recovered continence as before. Conclusions: Synthetic mesh in the suburethral tape systems for stress urinary incontinence correction should be polypropylene, macropore and monofilament. These characteristics enable better bio integration, theoretically reducing the number of complications (vaginal wall erosion, exposition and over infection). In relation with the failure of the silicone fixation system, no other casers have been reported in follow-up studies between 12 and 36 months (mean follow-up 14 and 18 months), so hat studies with long-term follow-up will be able to determine if this is an isolated case or there will be others.

Vicente, Solà Dalenz; Jack, Pardo Schanz; Paolo, Ricci Arriola; Enrique, Guiloff Fische.

108

Malla de polipropileno multifilamento con autofijación de silicona exteriorizada a vagina / Multifilament polypropylene mesh with exteriorization of the silicone anchorage to the vagina  

Scientific Electronic Library Online (English)

Full Text Available SciELO Spain | Language: Spanish Abstract in spanish Objetivo: Describir un caso de falla de en una cirugía de cinta suburetral para corrección de la incontinencia de orina de esfuerzo con sistema Safyre VS (vaginal-suprapubic approach) multifilamento, a los 34 meses de buena evolución. Método: Descripción del caso y su resolución. Resultado: Se prese [...] ntó con descenso del sistema de sujeción lateral y erosión de la mucosa vaginal con exposición de la cinta e infección. Se retiró con gran facilidad el sistema de anclaje de silicona que se encontraba suelto y se colocó una nueva cinta suburetral con sistema TVT-O, recuperando la continencia antes lograda. Conclusiones: La malla sintéticas de los sistemas de corrección con cinta suburetral para la incontinencia de orina de esfuerzo, deben ser de polipropileno, macroporo y monofilamento. Estas características permiten una mejor biointegración, reduciendo teóricamente el número de complicaciones (erosión de pared vaginal, exposición y sobreinfección). Respecto a la falla del sistema de sujeción de silicona, ya que no se han informado otros casos en los estudios de seguimiento entre 12 y 36 meses (media 14 y 18 meses), sólo los estudios que contemplen seguimientos a largo plazo permitirán decir si se trata de un caso aislado o aparecerán otros. Abstract in english Objectives: To describe the failure of one case of suburethral tape for the correction of the stress urinary incontinence with the multifilament Sapphire VS (vaginal-suprapubic approach) system after 34 months of good outcome. Methods: Description of the case and its resolution. Results: The patient [...] presented with a descent of the lateral fixation and erosion of the vaginal mucosa with exposure of the mesh and infection. The silicone fixation system, which was loose, was retrieved very easily and a new suburethral mesh with the system TVT-O was inserted; the patient recovered continence as before. Conclusions: Synthetic mesh in the suburethral tape systems for stress urinary incontinence correction should be polypropylene, macropore and monofilament. These characteristics enable better bio integration, theoretically reducing the number of complications (vaginal wall erosion, exposition and over infection). In relation with the failure of the silicone fixation system, no other casers have been reported in follow-up studies between 12 and 36 months (mean follow-up 14 and 18 months), so hat studies with long-term follow-up will be able to determine if this is an isolated case or there will be others.

Vicente, Solà Dalenz; Jack, Pardo Schanz; Paolo, Ricci Arriola; Enrique, Guiloff Fische.

1099-11-01

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Impact of pregnancy and vaginal delivery on the passive and active mechanics of the rat vagina.  

Science.gov (United States)

Remodeling of vaginal extracellular matrix and smooth muscle likely plays a critical role in reducing the risk of maternal injury during vaginal delivery by altering the mechanical properties to increase distension and reduce stress. Long-Evans rats were divided into five groups to examine the passive mechanical and active contractile properties throughout pregnancy and postpartum: virgin (n=17), mid-pregnant (Day 14-16, n=12), late-pregnant (Day 20-22, n=14), immediate postpartum (0-2 h after delivery, n=14), and 4 week postpartum (n=15). Longitudinal sections of vaginal tissue were loaded to failure uniaxially for passive mechanical or active contractile properties were examined. For passive mechanics, the tangent modulus decreased 45% by mid-pregnancy and immediately postpartum (pconsistent with what would be expected from a tissue that is remodeling to maximize its ability to distend at the time of vaginal delivery to facilitate passage of the fetus with minimal injury. PMID:20824342

Feola, Andrew; Moalli, Pamela; Alperin, Marianna; Duerr, Robbie; Gandley, Robin E; Abramowitch, Steven

2011-01-01

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Sheila Jeffreys: The Industrial Vagina. The Political Economy of the Global Sex Trade. London: Routledge 2008.  

Directory of Open Access Journals (Sweden)

Full Text Available Sheila Jeffreys analysiert die Prozesse, die zu einer Industrialisierung und Globalisierung von Prostitution im späten 20. und 21. Jahrhundert geführt haben. Hauptverantwortlich für die gegenwärtige Diskursverschiebung um Prostitution ist für Jeffreys zum einen die sexuelle Revolution der 1970er Jahre und zum anderen die massive Finanzierung von Unterstützer/-innen der Sexarbeiterinnen zur HIV-Prävention in den 1980ern. Jeffreys legt wie in früheren Arbeiten ihre radikal-feministische Position dar und fordert eine Abschaffung der Prostitution. In ihrer Abrechnung mit dem liberalen feministischen Diskurs, für den eine Unterstützung von Sexarbeiterinnen prioritär ist, ignoriert sie die Widersprüchlichkeiten und Komplexitäten der gelebten Realitäten. An vielen Stellen ihres Buches bekräftigt Jeffreys stereotypische Männlichkeitsvorstellungen, was durch einen Blick über den Tellerrand des ihr vertrauten wissenschaftlichen Bezugsrahmens hätte vermieden werden können.Sheila Jeffreys analyzes the processes that led to the industrialization and globalization of prostitution in the late 20th and 21th centuries. Jeffreys considers those primary factors responsible for the current shift in discourse on prostitution, which can be attributed to the sexual revolution of the 1970s on the one hand, and to massive financing of HIV prevention in the 1980s by sex worker supporters on the other. As in earlier studies, Jeffreys presents readers with her radical-feminist position and demands prostitution be abolished. In her confrontation with liberal-feminist discourse, in which the support of sex workers takes priority, she ignores the inconsistencies and complexities of real lived experience. At many points throughout her book, Jeffreys affirms stereotypical male conceptions, which could have been avoided had she looked beyond the theoretical frame of reference that makes up her comfort zone.

Susanne Hofmann

2010-03-01

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Modification of the gluteal perforator-based flap for reconstruction of the posterior vagina.  

Science.gov (United States)

Vaginal reconstruction after pelvic exenteration not only affords significant psychological benefit, it also decreases the morbidity and mortality associated with pelvic exenteration. In irradiated patients filling the surgical defect with healthy, well-vascularized tissue, such as omental flaps, colonic advancements, and myocutaneous flaps, has been shown to decrease the incidence of fistulas, bowel obstructions, infections, and hemorrhage. A novel use of the gluteal perforator-based flap is described in the unique circumstance of posterior pelvic exenteration with sacrectomy. PMID:10910255

Judge, B A; García-Aguilar, J; Landis, G H

2000-07-01

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In vitro probiotic properties of Lactobacillus fermentum SK5 isolated from vagina of a healthy woman.  

Science.gov (United States)

A lactobacillus strain isolated from a vaginal tract of a healthy woman was examined in vitro for its probiotic potential. This strain, identified as Lactobacillus fermentum SK5, was able to survive at pH 3-4 and 0.1-0.2% bile, and unaffected by pepsin (3 g l(-1)) and pancreatin (1 g l(-1)), but was susceptible to all tested antibiotics except metronidazole. L. fermentum SK5 had an antimicrobial potential against gastrointestinal pathogenic Escherichia coli and vaginal pathogenic Gardnerella vaginalis. The effective substance was suspected to be a bacteriocin-like compound with a molecular weight of more than 10 kDa, but hydrogen peroxide was also detected. Further studies revealed that L. fermentum SK5 had good autoaggregation characteristic and a high surface hydrophobicity that enhanced its adhesion ability to epithelial cells and for biofilm formation. This lactobacillus showed coaggregation with E. coli and G. vaginalis to affect their adhesion and colonization. The adhesion of L. fermentum SK5 to HeLa, HT-29 and Caco-2 cells and its inhibition of E. coli and G. vaginalis adherence to these cells were demonstrated. These incidences provided evidence of the possible colonization of L. fermentum SK5 that would prevent binding and growth of E. coli and G. vaginalis onto intestinal and vaginal epithelial cells. On the basis of the ability of L. fermentum SK5 to inhibit pathogenic microorganisms through coaggregation and antimicrobial substances, it is likely that this lactobacillus strain could be a potential probiotic candidate for beneficial use in protecting against gastrointestinal and vaginal microbial infections. PMID:23624069

Kaewnopparat, Sanae; Dangmanee, Nattakan; Kaewnopparat, Nattha; Srichana, Teerapol; Chulasiri, Malyn; Settharaksa, Sukanya

2013-08-01

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Radiotherapy for carcinoma of the vagina. Immunocytochemical and cytofluorometric analysis of prognostic factors  

International Nuclear Information System (INIS)

Background and purpose: The aim of this study was to assess the potential prognostic factors in patients with primary invasive vaginal carcinoma (PIVC) treated with radical irradiation. Patients and methods: The analysis was performed on 77 patients with PIVC treated between 1985 and 2005 in the Maria Sklodowska-Curie Memorial Institute of Oncology, Cancer Center in Krakow. A total of 36 patients (46.8 %) survived 5 years with no evidence of disease (NED). The following groups of factors were assessed for potential prognostic value: population-based (age), clinical (Karnofsky Performance Score [KPS], hemoglobin level, primary location of the vaginal lesion, macroscopic type, length of the involved vaginal wall, FIGO stage), microscopic (microscopic type, grade, mitotic index, presence of atypical mitoses, lymphatic vessels invasion, lymphocytes/plasmocytes infiltration, focal necrosis, VAIN-3), immunohistochemical (protein p53 expression, MIB-1 index), cytofluorometric (ploidity, index DI, S-phase fraction, proliferation index SG2M) factors. Results: Significantly better 5-year NED was observed in patients: < 60 years, KPS ? 80, FIGO stage I and II, grade G1-2, MIB-1 index < 70, S-phase fraction < 10, and proliferation index < 25. Independent factors for better prognosis in the multivariate Cox analysis were age < 60 years, FIGO stage I or II, and MIB-1 index < 70. Conclusion: Independent prognostic factors in the radically irradiated PIVC patients were as follows: age, FIGO stage, MIB-1 index. (orig.)

114

High-dose rate brachytherapy (HDRB for primary or recurrent cancer in the vagina  

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Full Text Available Abstract Purpose The purpose of this study was to evaluate the efficacy of HDR brachytherapy for primary or recurrent vaginal cancer. Methods Between the years 2000 to 2006, 18 patients with primary or recurrent vaginal cancer were treated with brachytherapy (HDRB. Six patients had primary vaginal cancer (stage II to IVA while 12 were treated for isolated vaginal recurrence (primary cervix = 4, vulva = 1 and endometrium = 7. Five patients had previous pelvic radiation therapy. All except one patient received external beam radiation therapy to a median dose of 45 Gy (range 31.2–55.8 Gy. The HDRB was intracavitary using a vaginal cylinder in 5 patients and interstitial using a modified Syed-Nesblett template in 13 patients. The dose of interstitial brachytherapy was 18.75 Gy in 5 fractions delivered twice daily. The median follow-up was 18 months (range 6–66 months. Results Complete response (CR was achieved in all but one patient (94%. Of these 17 patients achieving a CR, 1 had local recurrence and 3 had systemic recurrence at a median time of 6 months (range 6–22 months. The 2-year actuarial local control and cause-specific survival for the entire group were 88% and 82.5%, respectively. In subset analysis, the crude local control was 100% for primary vaginal cancer, 100% for the group with recurrence without any prior radiation and 67% for group with recurrence and prior radiation therapy. Two patients had late grade 3 or higher morbidity (rectovaginal fistula in one patient and chronic vaginal ulcer resulting in bleeding in one patient. Both these patients had prior radiation therapy. Conclusion Our small series suggests that HDRB is efficacious for primary or recurrent vaginal cancer. Patients treated with primary disease and those with recurrent disease without prior irradiation have the greatest benefit from HDRB in this setting. The salvage rate for patients with prior radiation therapy is lower with a higher risk of significant complications. Additional patients and follow-up are ongoing to determine the long-term efficacy of this approach.

Kelley Joseph L

2008-02-01

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Radiotherapy of primary carcinoma of the vagina: management and results of different therapy schemes  

International Nuclear Information System (INIS)

Three hundred and sixty-two cases of primary vaginal carcinoma were treated at the Irradiation Department of the University Clinic for Obstetrics and Gynecology, Vienna, from 1950 to 1977. As the method of choice an individually dosed, fractioned, and protracted radium-telecobalt therapy was employed. Comparing the last period analyzed (1971-1977) with another period 20 years earlier (1951-1956), a marked increase of advanced stages and older patients can be observed. These changes are reflected in the 5-year remission rate: in the total population it was 39.8%, as compared to 32% for the period from 1971 to 1977. For a group of 99 patients, who were treated between 1971 and 1977, the therapeutic effect of different therapy schemes is reported. The benefit of teletherapy is remarkable for advanced states, whereas for stages I and II an intrauterine application may be of importance. The complication rate amounted to 8% recto- or vesicovaginal fistulas and 41% and 43% cystitis and proctitis. The central importance of gynecological screening, especially for older women, is emphasized

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'The vagina does not talk': conception concealed or deliberately disclosed in eastern Cameroon.  

Science.gov (United States)

In the East Province of Cameroon, respectable womanhood has long been intrinsically related to ethics of production and reproduction: women attain social standing through productive work in the fields and through the reproduction of children - preferably within a marital setting. Yet, in the face of current alternative 'horizons of honour' such as schooling, employment or relationships with rich urban men, women's intentions with regard to marriage and motherhood acquire different meanings. On their pathways to urban forms of honour, formal engagements and childbearing are often postponed, while premarital sexual encounters proliferate. This paper explores the meanings of pregnancy within the context of these fragile relationships and women's urban aspirations; fertility will be shown to be a 'bet' that may either disrupt or stabilize urban affairs and ambitions. As such, pregnancies can be strategically anticipated and deliberately disclosed or unexpectedly encountered and secretly disrupted. This paper sheds light on women's strategies of concealment and disclosure of pregnancies and shows that these practices are often inspired by a notion of the 'right timing' of particular reproductive conjunctures - a notion that is of increasing relevance in current frames of female honour in Cameroon. PMID:22118422

van der Sijpt, Erica

2012-01-01

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Cistectomía radical laparoscópica con extracción de pieza por vagina: Caso clínico / Laparoscopic radical cystectomy with vaginal specimen extraction: Case report  

Scientific Electronic Library Online (English)

Full Text Available SciELO Spain | Language: Spanish Abstract in spanish Objetivo: Presentar la utilidad de una técnica minimamente invasiva como herramienta terapéutica en el tratamiento de un paciente de edad avanzada portador de cáncer de vejiga musculoinvasor. Método: Paciente femenina de 78 años con cáncer de vejiga avanzado que debuta con hematuria. Se realiza cist [...] ectomía radical con linfadenectomía pelviana por vía laparoscópica con extracción de pieza quirúrgica por vía vaginal. Resultados: El tiempo operatorio fue de 240 minutos con un sangrado de 200 ml y una estadía hospitalaria de 8 días. La paciente evolucionó favorablemente y tras un seguimiento de 6 meses se encuentra sin evidencia de recidiva tumoral. Conclusión: El bajo impacto quirúrgico permite que este abordaje pueda ser utilizado en casos seleccionados para evitar la severa morbilidad indefectiblemente asociada a la progresión local del cáncer de vejiga avanzado. Abstract in english Objective: To report a case of laparoscopic radical cystectomy and pelvic lymphadenectomy with vaginal extraction of the surgical specimen in an elderly patient with muscle invasive bladder tumor. Method: A 78 year old patient with history of hematuria was diagnosed of muscle invasive bladder cancer [...] . Lapa-roscopic radical cystectomy and pelvic lymphadenectomy with vaginal extraction of the surgical specimen was performed without incident. Results: Operative time was 240 minutes, surgical bleeding was 200 ml and hospital stay 8 days. The patient evolved uneventfully and remains disease free after 9 months of follow-up. Conclusion: Laparoscopic radical cystectomy provides adequate oncologic results with decreased morbidity, making this surgery an attractive alternative for the management of patients in a delicate condition.

Gonzalo, Vitagliano; Nicolas, Villasante; Juan, Paterlini; Carlos, Ameri; Osvaldo, Mazza.

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Obstructed labour caused by foetal congenital hydronephrosis. Trans-abdominal drainage of the hydronephrosis with resultant delivery per vagina  

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Full Text Available A case of a 25 year old 2 alive Patient, with obstructed labour with fetal death and delivery of the fetus up to the trunk caused by congenital Bilateral Hydronephrosis is presented. Obstetric examination on admission supported by Abdominal Ultrasound revealed Bilateral Hydronephrosis which was then drained per abdomen using needle and intravenous fluid giving set with eventual relief of the obstruction and vaginal delivery of the stillborn baby.

Ishaq Funsho Abdul

2013-01-01

119

Comparative study vagina mould/ fletcher applicator in MRI guided pulsed rate brachytherapy in patients reached by an uterine cervix carcinoma  

International Nuclear Information System (INIS)

This study began in february 2009 and included until today ten patients. twenty patients are planned. The analysis of preliminary results show a much higher tolerance for the vaginal cast device. The dosimetry data were the object of a preliminary study that seems demonstrate an equivalence of the both modalities, with differences concerning the doses to critical organs; The definitive result swill be presented with the data including the twenty planned patients. (N.C.)

120

Sodium tetradecyl sulphate direct intralesional sclerotherapy of venous malformations of the vulva and vagina: report of five cases.  

Science.gov (United States)

We report five cases of female patients affected by symptomatic focal external genital venous malformations treated with percutaneous direct intralesional injection of sodium tetradecyl sulphate (STS). All patients were referred because of discomfort and pain when sexual intercourse was attempted. Direct sclerotherapy with 3% STS was performed on a day-hospital basis with the patient under local anesthesia. Complete resolution of the symptoms was achieved in all cases. No major adverse effects were reported. Direct intralesional sclerotherapy with STS may be considered a safe and effective method for the treatment of female external genital malformation without the necessity of general anesthesia for pain control. PMID:20559638

Krokidis, Miltiadis; Venetucci, Pietro; Hatzidakis, Adam; Iaccarino, Vittorio

2011-02-01

 
 
 
 
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HUBUNGAN AKTIVITAS SEKSUAL PADA USIA DINI, PROMISKUITAS DAN BILAS VAGINA DENGAN KEJADIAN KANKER LEHER RAHIM PADA PASIEN ONKOLOGY DI RSUD Dr.MOEWARDI SURAKARTA  

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Background: Cervical cancer ranks the top cause of cancer deaths in developing countries. At Dr. Moewardi Hospital Surakarta cervical cancer was found in most cancers. Risk factors associated with health and cleanliness of the female reproductive tract can increase the incidence of cervical cancer. Purpose this study aims to determine factors associated with female reproductive health tract and the occurrence of cervical cancer. Method: The study was a quantitative analytical research used cr...

. Ridhaningsih; Sitti Nur Djannah

2013-01-01

122

Penetrating injury of the vagina, bladder and omentum in a woman with 5 months gestation: case report and review of the literature.  

Science.gov (United States)

Intra-peritoneal bladder and visceral injuries from impalement of the perineum in women are exceedingly rare. This kind of injury has not been previously reported in a pregnant woman. The evaluation and surgical management of a pregnant woman is a challenging surgical problem. Preoperative evaluation of the uterus and fetus is balanced with minimal use of radiographic studies. Multiple organs can be damaged with this type of injury, necessitating careful evaluation and operative planning. We report a rare case of transvaginal impalement injury with through-and-through bladder rupture and intra-peritoneal injury in a 5 months pregnant woman. We discuss diagnostic and management strategies and review the literature. PMID:24366762

Zhang, Chao; Liu, Qiang; Li, Bo-Jun; Bi, Gang; Yi, Ping; Li, Ke; Zhang, Yong; Zhang, Ke-Qin; Li, Yan-Feng

2014-06-01

123

Robotic-Assisted Hysterectomy  

Medline Plus

Full Text Available ... vagina adjacent to the cervix, and it's what marks our incision between the vagina and the cervix. ... to perform support type procedures to prevent the post-hysterectomy vagina from descending or prolapsing, and as ...

124

Vaginal Birth  

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Full Text Available ... widened cervix, through the vagina to the outside world! This is the when the mother pushes with ... through the cervix and vagina to the outside world! The path the baby travels through is called ...

125

Healthy Sexuality  

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Full Text Available ... open, revealing the opening to the vagina. The uterus enlarges and rises upward into the abdomen. Also ... contractions of the pelvic floor, the vagina, and uterus. After orgasm, this process may be repeated or ...

126

Ovarian Cysts  

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Full Text Available ... they may be diagnosed and treated. Anatomy Vagina Uterus Fallopian Tubes Ovaries The female reproductive organs include: • the ovaries • the Fallopian tubes • the uterus • the vagina The female reproductive organs are located ...

127

Endometriosis  

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Full Text Available ... better and review some treatment options. Anatomy Vagina Uterus Fallopian Tubes Ovaries The female reproductive organs include: • the vagina • the uterus • the Fallopian tubes • the ovaries The female reproductive ...

128

Menopause  

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Full Text Available ... Anatomy The female reproductive organs include the: • vagina • uterus • fallopian tubes • ovaries The female reproductive organs are ... between the urinary bladder and the rectum. Vagina Uterus Fallopian Tubes Ovaries The ovaries are glands, with ...

129

Dilation and Curettage  

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Full Text Available ... can be treated or diagnosed with it. Vagina Uterus Fallopian Tubes Ovaries Anatomy The female reproductive organs include: • the vagina • the uterus • the fallopian tubes • the ovaries The female reproductive ...

130

Ovarian Cancer  

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Full Text Available ... ovarian cancer is detected and treated. Anatomy Vagina Uterus Fallopian Tubes Ovaries The female reproductive organs include: • The vagina • The uterus • The Fallopian tubes • The ovaries. The female reproductive ...

131

Pap Smear  

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Full Text Available ... and why it is beneficial. Ovaries Fallopian Tubes Uterus Vagina Anatomy This document is for informational purposes ... The female reproductive organs include: • The vagina • The uterus • The Fallopian tubes • The ovaries These organs are ...

132

Colposcopy  

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Full Text Available ... indications, and possible risks and complications. Anatomy Vagina Uterus Fallopian Tubes Ovaries The female reproductive organs include: • the vagina • the uterus • the Fallopian tubes • the ovaries The female reproductive ...

133

Ovarian Cancer  

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Full Text Available ... treated. Anatomy Vagina Uterus Fallopian Tubes Ovaries The female reproductive organs include: • The vagina • The uterus • The Fallopian tubes • The ovaries. The female reproductive organs are located in the pelvis between ...

134

Endometriosis  

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Full Text Available ... options. Anatomy Vagina Uterus Fallopian Tubes Ovaries The female reproductive organs include: • the vagina • the uterus • the Fallopian tubes • the ovaries The female reproductive organs are located in the pelvis, between ...

135

Uterine Fibroids  

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Full Text Available ... options. Anatomy Vagina Uterus Fallopian Tubes Ovaries The female reproductive organs include: • The vagina • The uterus • The Fallopian tubes • The ovaries The female reproductive organs are located in the pelvis, between ...

136

Dilation and Curettage  

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Full Text Available ... it. Vagina Uterus Fallopian Tubes Ovaries Anatomy The female reproductive organs include: • the vagina • the uterus • the fallopian tubes • the ovaries The female reproductive organs are located in the pelvis, between ...

137

Colposcopy  

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Full Text Available ... complications. Anatomy Vagina Uterus Fallopian Tubes Ovaries The female reproductive organs include: • the vagina • the uterus • the Fallopian tubes • the ovaries The female reproductive organs are located in the pelvis, between ...

138

Healthy Sexuality  

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Full Text Available ... Her vagina is lubricated by secretions from the walls of the vagina. The vaginal muscles relax, causing ... desire that she may not have had at first. Sometimes people worry about their sexual health and ...

139

Pap Smear  

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Full Text Available ... your feet in the stirrups. The doctor or nurse will then gently open your vagina and insert a speculum. A speculum is a specialized instrument that keeps the vagina open so that a health care provider can see and reach inside the vagina ...

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Colpopéxia transcoccígea con malla de polipropileno con orificios facilitadores de la integración en la corrección del prolapso de la pared posterior de la vagina: resultados anatómicos y funcionales / Transcoccigeal colpopexy with polyprolylene mesh with helper orifices for the treatment of posterior vaginal wall prolapse: anatomical and functional results  

Scientific Electronic Library Online (English)

Full Text Available SciELO Spain | Language: Spanish Abstract in spanish Objetivo: La creación de neoligamentos útero- sacros, según lo descripto por Petros, con el uso de malla sintética de polipropileno permite la corrección anatómica del prolapso posterior en los tres niveles propuestos por DeLancey. El objetivo de este estudio es evaluar los resultados anatómicos y f [...] uncionales de este método en la corrección del POP posterior. Pacientes y método: Desde diciembre del 2004 a marzo del 2007, 34 mujeres con edad media de 63 años fueron sometidas al procedimiento, siendo rectoceles grado III o mayores. El seguimento mínimo fué de 13 meses. Los puntos de fijación fueron el músculo íleococcígeo y el ligamento sacroespinoso. Técnica: Luego de la incisión de la mucosa de la pared vaginal posterior, la fosa ísquio-rectal es disecada. Dos pequeñas incisiones son hechas 3 cm lateral y 3 cm inferior al ano. La aguja se inserta verticalmente en dirección a la espina isquiática, guiado por el dedo indicador del cirujano hasta el ligamento sacroespinoso, 2 cm medialmente, evitando a lesión del canal de Alcock. Los brazos de la malla son conectados a la punta de la aguja, traccionando posteriormente de las agujas. No se realiza la correción sitio específica. El exceso de malla es recortado y esta se fija próxima al cuerpo perineal, quedando de esa forma extendida sobre la pared vaginal posterior. La mucosa vaginal se cierra en forma habitual. Resultados: Con el 94,7% de cura y recurrencia del 5,3%, no hubo lesión nerviosa, visceral o vascular. Cinco (14,7%) pacientes tuvieron exposición de la malla de menos de 1 cm² y fueron tratadas conservadoramente sin impacto en los resultados. Dos de las 17 sexualmente activas (11,8%) presentaron dispareunia transitoria, siendo prolongada en 1 solo caso (5,9%) Conclusión: Este procedimiento mínimamente invasivo es una alternativa atractiva para la reconstrucción anatómica y funcional de los defectos posteriores y apicales. Abstract in english Objective: The creation of neo utero-sacral neoligaments, decribed by Petros, evolved into a new procedure allowing for the anatomical reconstruction of the three levels proposed by DeLancey. The aim of this study is evaluate the anatomical and functional outcomes of this minimally invasive procedur [...] e. Patients and method: From December 2004 to March 2007, a total of 34 patients with posterior defect grade III or higher underwent this procedure. The minimum follow up was 13 months Mean age was 63 years. The site of fixation was the Sacrospinous ligament. Surgical technique: The ischiorectal fossa is dissected. Next two small skin incisions are made 3 cm lateral and inferior to the center of the anus. A proper needle is introduced, vertically towards the sacrospinal ligament at the level of the ischial spine, guided by the surgeon index finger, 2 cm medially avoiding the Alcok canal. The armpit of the mesh is connected to the tip of the needle and brought to the perineal region. No site specific correction is made. Results: The cure rate was 94,7% and recurrence rate was 5,3%. No visceral, nerurovascular injuries were observed. The mesh exposure rate (less than 1 cm²) was (14.7%) and all patients were treated conservatively with no impact on the outcome. There were transient dyspareunia in 2 (11.8%) of the 17 sexually active patient and persistent in 1 case (5.9%). Conclusions: This procedure is an attractive minimally invasive alternative for the anatomical and functional reconstruction of the posterior and apical defects.

Vitor, Pagotto; Paulo, Palma; Cassio, Riccetto; Miguel, Bigozzi.

 
 
 
 
141

Comparative study vagina mould/ fletcher applicator in MRI guided pulsed rate brachytherapy in patients reached by an uterine cervix carcinoma; Etude comparative moule vaginal/applicateur de fletcher en curietherapie de debit pulse guide par IRM chez les patientes atteintes d'un cancer du col uterin  

Energy Technology Data Exchange (ETDEWEB)

This study began in february 2009 and included until today ten patients. twenty patients are planned. The analysis of preliminary results show a much higher tolerance for the vaginal cast device. The dosimetry data were the object of a preliminary study that seems demonstrate an equivalence of the both modalities, with differences concerning the doses to critical organs; The definitive result swill be presented with the data including the twenty planned patients. (N.C.)

Francois, G.; Dumas, I.; Mazeron, R.; Verezesan, O.; Monnier, L.; Vieillot, S.; Gensse, M.C.; Haie-Meder, C. [Institut Gustave-Roussy, 94 - Villejuif (France)

2009-10-15

142

HIV and AIDS  

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Full Text Available ... digestive tract and lungs and often affects the skin. Cervical cancer is cancer of the cervix. The cervix is ... vagina from the uterus. Non Hodgkin's lymphoma is cancer that starts in the ... through tiny cuts or sores on the skin or the lining of the vagina, penis, rectum ...

143

Wnt family genes and their modulation in the ovary-independent and persistent vaginal epithelial cell proliferation and keratinization induced by neonatal diethylstilbestrol exposure in mice  

International Nuclear Information System (INIS)

Proliferation and differentiation of cells in female reproductive organs, the oviduct, uterus and vagina, are regulated by endogenous estrogen. In utero exposure to a synthetic estrogen, diethylstilbestrol (DES), induces vaginal clear-cell adenocarcinoma in humans. In mice, perinatal exposure to DES results in abnormalities such as polyovular follicles, uterine circular muscle disorganization and persistent vaginal epithelial cell proliferation. We reported the persistent gene expression change such as interleukin-1 (IL-1) related genes, insulin-like growth factor-I (IGF-I) and its downstream signaling in the mouse vagina exposed neonatally to DES. In this study, we found persistent up-regulation of Wnt4 and persistent down-regulation of Wnt11 in the vagina of mice exposed neonatally to DES and estrogen receptor ? specific ligand. Also Wnt4 expression in vagina is correlated to the stratification of epithelial cells with the superficial keratinization of vagina, but not epithelial cell stratification only.

144

Progesterone receptors in the female lower urinary tract  

International Nuclear Information System (INIS)

When female estrogenized rabbits were injected i.v. with 3H-progesterone, the tritium concentration determined after one hour was about two to three times higher in urethra, urinary bladder and vagina than in the heart. High affinity progesterone receptors (KD = 1-2 nM) could be demonstrated in both cytoplasmic and nuclear fractions prepared from estrogenized rabbit urethra, bladder and vagina. The cytosolic receptor concentration in both urethra and bladder was about half of that in the vagina. The concentration of nuclear receptors in urethra was not significantly different from that in the vagina, but in the bladder the concentration was only about one fourth of that in the vagina or urethra. The mean KD of cytosolic receptors from bladder was significantly higher than the corresponding values in urethra and vagina. Progesterone binding sites in the bladder had a broader hormonal specificity than those in the urethra or vagina. The present demonstration of specific progesterone receptors in the female urethra might provide a possible link between estrogen progesterone interaction and the appearance of urinary incontinence during pregnancy in women

145

Robot-Assisted Gynecologic Oncology Surgery  

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Full Text Available ... predictive that under the microscope they'll be negative. 00:42:05 JENNIFER HALL: So when you ... it out through the vagina. So there's a number of ways to do this. And we've ...

146

Bleomycin  

Science.gov (United States)

Bleomycin injection is used alone or in combination with other medications to treat head and neck cancer ( ... and vulva (the outer part of the vagina). Bleomycin is also used to treat Hodgkin's lymphoma (Hodgkin's ...

147

Robotic-Assisted Hysterectomy  

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Full Text Available ... much less, and I think that makes a big difference for recovery for these patients. 00:32: ... may have better luck. It looks kind of big for her vagina. Sorry, Dr. Tulikangas. 00:37: ...

148

A case of a bitch with imperforate hymen and hydrocolpos.  

Science.gov (United States)

A 38-month-old female Golden retriever was presented with dysuria and dyschezia. It was difficult to visualize the vagina by vaginoscopy due to a cystic polyp on the hymen. The polyp was 2 x 3 cm in diameter, round, and pink in color. From clinical and imaging evaluations the original diagnosis was mucometra or pyometra. From endoscopic examination of the vagina an imperforate hymen was finally diagnosed. The ovaries, uterus, and half of the vagina were removed through a median abdominal incision. The vagina contained about 1.5 liters of fluid, but the uterus and ovaries appeared normal. This is a rare case with imperforate hymen and hydrocolpos with a polyp on the hymenal membrane in bitch. PMID:11346188

Tsumagari, S; Takagi, K; Takeishi, M; Memon, M A

2001-04-01

149

Vaginal Atrophy  

Science.gov (United States)

... vagina before intercourse. Lubricants (oil-based), such as olive oil, vegetable oil, or other products Use at ... Resources Diseases and Conditions Adrenal Disorders Osteoporosis and Bone Health Children and Teen Health Diabetes Heart Health ...

150

What Are the Different Types of Contraception?  

Science.gov (United States)

... and forms, including foam, jelly, cream, suppository, and film. A spermicide should be inserted into the vagina ... any woman who has high blood pressure, a history of blood clots, or a history of breast, ...

151

Bleeding during Pregnancy  

Science.gov (United States)

... The tissue may be removed by dilation and curettage (D&C) . It also may be removed by ... uterus, which protrudes into the vagina. Dilation and Curettage (D&C): A procedure in which the cervix ...

152

Vaginal Birth  

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Full Text Available ... babies vaginally. However, some situations make vaginal delivery dangerous. In these cases, the doctor may decide to ... through the cervix and vagina to the outside world! The path the baby travels through is called ...

153

Colposcopy  

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Full Text Available ... prevent some of the viral infections that can cause cervical cancer. Make sure to ask your healthcare ... that will help it heal faster. This may cause a thick brownish-black discharge from the vagina ...

154

Hysterectomy  

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Full Text Available ... behind the vagina and uterus. Symptoms and Their Causes Many conditions may result in the need for ... conditions result in excessive menstrual bleeding that can cause significant blood loss. Significant cramps and abdominal discomfort ...

155

Expanding Patient Options: Minilaparotomy for Hysterectomy  

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Full Text Available ... specimen below the uterine artery. Again, for better visualization, I have removed the cervix on all but ... the Impact LigaSure, but, again, you have full visualization of the vagina. There have been a few ...

156

Menopause  

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Full Text Available ... strokes and blood clots in the lungs and legs. The Vagina Body tissue in the genital area ... Strokes 3. Blood clot in the lungs and legs, and 4. Breast cancer This same combination was ...

157

Episiotomy  

Science.gov (United States)

... that widens the opening of the vagina during childbirth. It is a cut to the perineum -- the ... Not every woman will need an episiotomy during childbirth. Many women get through childbirth without tearing on ...

158

Laparoscopic Supracervical Hysterectomy  

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Full Text Available ... the thermal spread on this instrument is a third of what several of our earlier instruments were. ... you should still be followed because the top third of the vagina develops from the same tissue ...

159

Pregnancy - 1st Trimester: Questions to Discuss with Your Doctor  

Science.gov (United States)

... Pregnancy: 1st Trimester Questions to Discuss with Your Doctor: Your age and how it will affect your ... you having any bleeding from your vagina? Your Doctor Might Examine the Following Body Structures or Functions: ...

160

Microflora of urogenital tract in pregnancy with asymptomatic bacterium  

International Nuclear Information System (INIS)

The article contains results of research interrelationship from colonization of vagina and urinary tract diseases. E.coli one of the main factors in development asymptomatic bacterium. Presented high effects of penicillin medicaments and nitrofurans in treatment of asymptomatic bacterium

 
 
 
 
161

Gonorrhea (For Parents)  

Science.gov (United States)

... testicles. Females may have lower abdominal pain, painful intercourse, and abnormal bleeding from the vagina. Gonorrhea can ... had any type of sex (vaginal, oral, or anal) should be screened regularly for STDs so that ...

162

Vaginal yeast infection  

Science.gov (United States)

Yeast infection - vagina; Vaginal candidiasis; Monilial vaginitis ... Most women have a vaginal yeast infection at some time. Candida albicans is a common type of fungus. It is often found in small amounts in the ...

163

Robotic-Assisted Hysterectomy  

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Full Text Available ... down the balloon, Brenda, you may have better luck. It looks kind of big for her vagina. ... needed to remove periaortic lymph nodes. 00:43:27 PAUL K. TULIKANGAS, MD, FACOG, FACS: I have ...

164

Crohn's Disease  

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Full Text Available ... intestines Crohn's Disease can also cause sores that tunnel through the affected area into surrounding tissues such as the bladder, vagina, or skin. These tunnels, called fistulae, often become infected. Usually fistulae are ...

165

Crohn's Disease  

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Full Text Available ... surrounding tissues such as the bladder, vagina, or skin. These tunnels, called fistulae, often become infected. Usually ... Other problems associated with Crohn's Disease include: • arthritis • skin problems such as rashes and sores • inflammation in ...

166

Robotic-Assisted Laparoscopic Sacrocolpopexy for Vaginal Vault Prolapse  

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Full Text Available ... well as an anterior repair -- anterior and posterior repair. However, when we got in there we found remnants that mesh that was not at all attached to her vagina but certainly attached to her sacrum. Yeah. So ...

167

General Information About Endometrial Cancer  

Science.gov (United States)

... radiation therapy to the pelvis. After surgery, a plastic cylinder containing a source of radiation may be placed in the vagina to kill any remaining cancer cells. Radiation therapy alone for patients who cannot ...

168

Menopause  

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Full Text Available ... In fact, heart disease kills more women than lung or breast cancer. The following tips will help ... heart attacks, strokes and blood clots in the lungs and legs. The Vagina Body tissue in the ...

169

STDs and Pregnancy  

Science.gov (United States)

... opening to the womb), vagina, and external genitalia. Genital warts are symptoms of HPV infection that can be ... frequently increase in number and size during pregnancy. Genital warts often appear as small cauliflower-like clusters which ...

170

Vaginal Birth  

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Full Text Available ... 1. The vagina 2. The cervix 3. The uterus 4. The Fallopian tubes 5. The ovaries When ... egg goes down the Fallopian tube to the uterus. It may become fertilized along the way. If ...

171

Uterine Fibroids  

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Full Text Available ... Introduction Fibroids are common, benign tumors of the uterus. They can cause significant pain, as well as ... causes, symptoms, diagnosis, and treatment options. Anatomy Vagina Uterus Fallopian Tubes Ovaries The female reproductive organs include: • ...

172

C-Section  

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Full Text Available ... 1. The vagina 2. The cervix 3. The uterus 4. The Fallopian tubes 5. The ovaries When ... egg goes down the Fallopian tube to the uterus. It can become fertilized along the way. If ...

173

32 CFR 199.4 - Basic program benefits.  

Science.gov (United States)

...surgical sterilization procedure (male or female). (ii) Genetic testing...prolapsed vagina in a biological male who had undergone transsexual surgery...examinations following a sexual assault or domestic violence. The forensic examination...

2010-07-01

174

Pelvic Support Problems  

Science.gov (United States)

... applicators • Pelvic pressure that gets worse with standing, lifting, or coughing or as the day goes on ... may improve incontinence. • Pessaries—A pessary is a device that is inserted into the vagina to support ...

175

Masturbation  

Science.gov (United States)

... their vagina.” ) To avoid embarrassing your teen, feign ignorance of his or her habits: “I don’t ... Risky Behaviors Study Finds 2.5 Percent of Youths Have Participated in Sexting in Past Year AAP ...

176

Robotic-Assisted Hysterectomy  

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Full Text Available ... And by dividing this it allows me to enter the retroperitoneal space, or the potential spaces of ... get that safely. My goal is to not enter the vagina here, it's just to expose it, ...

177

Expanding Patient Options: Minilaparotomy for Hysterectomy  

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Full Text Available ... that’s not something we want as far to enter into. We are very comfortable as general OB- ... procedures. So you can see here I’m enter thing vagina and removing the cerv ix in ...

178

Chemotherapy  

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Full Text Available ... softeners. This helps decrease the chances of hemorrhoid formation and bleeding. Effect on the Skin and Nails ... vagina and increased pain with sexual intercourse. Lubricating, water-soluble jelly such as, KY Jelly ™, can help ...

179

Hysterectomy  

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Full Text Available ... in front of the vagina and uterus. The kidneys drain the urine into the bladder through 2 ... is very rare for the tubes connecting the kidneys to the bladder, as well as the bladder ...

180

Ovarian Cancer  

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Full Text Available ... in front of the vagina and uterus. The kidneys drain the urine into the bladder through 2 ... controls, causing an abnormal growth called a tumor. Kidney Bladder Urethra Ureter If the tumor does not ...

 
 
 
 
181

Endometriosis  

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Full Text Available ... in front of the vagina and uterus. The kidneys drain urine into the bladder through 2 tubes ... sure that other diseases, such as infections or kidney problems, are not the reason for the symptoms. ...

182

Types of Hymens  

Science.gov (United States)

Types of Hymens Posted under Health Guides . Updated 3 October 2014. +Related Content Hymen: a thin membrane that surrounds the opening to the vagina. Hymens can come in different shapes. The most common ...

183

Developmental disorders of the female reproductive tract  

Science.gov (United States)

... are related to intersex or ambiguous genitalia. Imperforate hymen -- The hymen is a thin tissue that partly covers the opening to the vagina. An imperforate hymen completely blocks the vaginal opening. This often leads ...

184

Female Reproductive System  

Science.gov (United States)

... one or more holes in it called the hymen partially covers the opening of the vagina. Hymens are often different from female to female. Most women find their hymens have stretched or torn after their first sexual ...

185

Cancer of the Cervix  

Science.gov (United States)

... partners • Early age at which you first had sex (younger than 18 years) Other risk factors include the following: • A personal history of dysplasia of the cervix, vagina, or vulva • A family history of cervical cancer • Smoking FREQUENTLY ASKED QUESTIONS ...

186

Amniocentesis  

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Full Text Available ... during this process, breathe slowly and relax the muscles of your abdomen. After the fluid is withdrawn, ... higher than 100 °F or 38 °C • Dizziness • Bleeding or fluid leakage from your vagina or from ...

187

Dilation and Curettage  

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Full Text Available ... curettage is and the possible diseases that can be treated or diagnosed with it. Vagina Uterus Fallopian ... goes down the fallopian tube, where it may be fertilized. This document is a summary of what ...

188

Crohn's Disease  

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Full Text Available ... a blood relative with an inflammatory bowel disease. Men and women are affected equally. Crohn's disease affects ... or stools may seep from the vagina. For men AND women with fistulae connecting the intestines to ...

189

Laparo-Endoscopic Single-Site (LESS) Procedure  

Medline Plus

Full Text Available ... need to do -- for example, get an appropriate lymph node or whatever. So there are some stones in ... a hysterectomy, and everything is extracted through the vagina -- or the chole and anti-reflux operation. Before ...

190

Vaginal Birth  

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Full Text Available ... The vagina 2. The cervix 3. The uterus 4. The Fallopian tubes 5. The ovaries When an ... cervix is 10 centimeters wide. This is about 4 inches. This is when the mother may be ...

191

Dilation and Curettage  

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Full Text Available ... The female reproductive organs are located in the pelvis, between the urinary bladder and the rectum. The ... These include: • Infection, in the vagina, uterus, or pelvis. • Bleeding, either during or after the operation. Other ...

192

Uterine Fibroids  

Medline Plus

Full Text Available Uterine Fibroids Introduction Fibroids are common, benign tumors of the uterus. They can cause significant pain, as well as ... located above and behind the vagina and uterus. Fibroids Uterine fibroids are benign tumors in the middle ...

193

21 CFR 884.4520 - Obstetric-gynecologic general manual instrument.  

Science.gov (United States)

...separating the edges of the vagina and holding back the tissue. (9) A gynecological fibroid hook is an instrument used to exert traction upon a fibroid. (10) A pelvimeter (external) is an instrument used to measure the external...

2010-04-01

194

Robotic-Assisted Laparoscopic Sacrocolpopexy for Vaginal Vault Prolapse  

Medline Plus

Full Text Available ... of the vasculature. Middle sacral vessels line the space as well as a number of venous plexuses, ... reasons. One would be difficulty dissecting the presacral space, difficulty suturing the mesh to the vagina and ...

195

Endometriosis  

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Full Text Available ... located above and behind the vagina and uterus. Pituitary Gland The pituitary gland, which is located at the base of the brain, controls the ovaries. The pituitary gland secretes hormones called LH and FSH, which cause ...

196

Endometriosis  

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Full Text Available ... above and behind the vagina and uterus. Pituitary Gland The pituitary gland, which is located at the base of the brain, controls the ovaries. The pituitary gland secretes hormones called LH and FSH, which cause ...

197

Biopsy - polyps  

Science.gov (United States)

Polyp biopsy ... are treated is the colon. How a polyp biopsy is taken depends on the location: Colonoscopy or flexible sigmoidoscopy explores the large bowel Colposcopy-directed biopsy examines the vagina and cervix Esophagogastroduodenoscopy (EGD) or ...

198

Menopause  

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Full Text Available ... the vagina during the menstrual period. The menstrual cycle is usually 28 days. The levels of estrogen ... of the many hormones that control the menstrual cycle. In addition to regulating the menstrual cycle, estrogen ...

199

Endometriosis  

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Full Text Available ... summary will help you understand endometriosis better and review some treatment options. Anatomy Vagina Uterus Fallopian Tubes ... timing in relation to your menstrual cycle. A physical examination, including a pelvic exam, must also be ...

200

Robotic-Assisted Hysterectomy  

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Full Text Available ... This incision in the vagina will be a full circle, and it will remove the cervix and ... benign disease, it's not as much of an issue because the uterus can be removed in pieces. ...

 
 
 
 
201

Expanding Patient Options: Minilaparotomy for Hysterectomy  

Medline Plus

Full Text Available ... from our laparoscopic experiences that we can perform full procedures internal ly. We can take out a ... using the Impact LigaSure, but, again, you have full visualization of the vagina. There have been a ...

202

Sexually Transmitted Diseases  

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Full Text Available ... hidden inside the vagina. Some women may not even know that they are infected! Herpes sores usually ... infected, you should have regular checkups for STDs, even if you do NOT notice symptoms. These tests ...

203

21 CFR 884.4530 - Obstetric-gynecologic specialized manual instrument.  

Science.gov (United States)

...uterus. (7) A gynecological surgical forceps is an instrument with two blades and...vagina. (14) A gynecological biopsy forceps is an instrument with two blades and handles...uterine sound, and gynecological biopsy forceps. The devices subject to this...

2010-04-01

204

Vaginal Birth  

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Full Text Available ... second stage of labor begins. Stage 2 The second stage of labor starts when the baby goes through the widened cervix, through the vagina to the outside world! This is the when the mother pushes with ...

205

C-Section  

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Full Text Available ... through the cervix and vagina to the outside world! The path the baby travels through is called ... is through the skin and abdominal wall. The second one is through the uterus. The incision through ...

206

Clotrimazole  

Science.gov (United States)

Clotrimazole is used to treat yeast infections of the vagina, mouth, and skin such as athlete's foot, ... Clotrimazole comes as a cream, lotion, powder, and solution to apply to the skin; lozenges (called troches) ...

207

Chronic Pelvic Pain  

Science.gov (United States)

... act as a muscular sling that supports the pelvic organs and openings of the vagina and sphincters and ... constipation or diarrhea can lead to pelvic floor dysfunction and pelvic pain can become very debilitating Men can suffer ...

208

Chronic Pelvic Pain in Women (Beyond the Basics)  

Science.gov (United States)

... with intercourse, or frequent/urgent urination. Pelvic floor dysfunction can be diagnosed by a clinician feeling the pelvic floor muscles (muscles that support the pelvic organs and hips) through the vagina and/or rectum; ...

209

Hysterectomy  

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Full Text Available ... through the vagina; this is known as laparoscopically assisted Some conditions, however, such as cervical or endometrial ... during surgery, your surgeon may discuss hormonal replacement therapy. Premenstrual symptoms, also known as PMS, are not ...

210

Ovarian Cancer  

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Full Text Available Ovarian Cancer Introduction Ovarian cancer is fairly rare. Ovarian cancer usually occurs in women who are over 50 years ... located above and behind the vagina and uterus. Cancer and its Causes The body is made up ...

211

Robotic-Assisted Laparoscopic Sacrocolpopexy for Vaginal Vault Prolapse  

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Full Text Available ... And you'll see that I think the tension on the anterior and posterior vagina are going ... appreciate. Now, the whole question is how much tension or should we put any tension on this ...

212

HIV and AIDS  

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Full Text Available ... the skin or the lining of the vagina, penis, rectum or mouth. Another common way of getting ... The treatment for AIDS focuses on suppressing the growth of the virus and improving the patient’s quality ...

213

40 CFR 798.4700 - Reproduction and fertility effects.  

Science.gov (United States)

...for possible future histopathological examination: Vagina...gross pathological changes. (d) Data and...pregnant, the types of change and the percentage...displaying each type of change. (2) Evaluation...description of all histopathological findings....

2010-07-01

214

C-Section  

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Full Text Available ... and the rectum. 1 2 3 4 4 5 5 The female reproductive organs include: 1. The vagina ... cervix 3. The uterus 4. The Fallopian tubes 5. The ovaries When an ovary releases an egg, ...

215

Hysterectomy  

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Full Text Available ... og010104 Last reviewed: 3/18/2009 1 The female reproductive organs include: • Vagina • Uterus • Fallopian tubes • And ... a positive solution for many serious conditions affecting female reproductive organs, causing pain, and bleeding. As you ...

216

Menopause  

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Full Text Available ... Last reviewed: 03/12/2012 1 Anatomy The female reproductive organs include the: • vagina • uterus • fallopian tubes • ovaries The female reproductive organs are located in the pelvis, between ...

217

C-Section  

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Full Text Available ... sections, it is important to know about the female reproductive organs. They are located in the pelvis, ... 1 2 3 4 4 5 5 The female reproductive organs include: 1. The vagina 2. The ...

218

Vaginitis test - wet mount  

Science.gov (United States)

... so the provider can see inside. A sterile, moist cotton swab is gently inserted into the vagina ... slightly among different laboratories. Some labs use different measurements or test different samples. Talk to your doctor ...

219

Gonorrhea  

Science.gov (United States)

... cause bleeding between periods, pain when urinating, and increased discharge from the vagina. If untreated, it can lead to pelvic inflammatory disease, which causes problems with pregnancy and infertility. Your ...

220

Dyspareunia: Painful Sex for Women  

Science.gov (United States)

... part of the genitals can cause pain during sex. Some conditions affect the skin around the vagina. ... types of birth control) does not fit correctly, sex may also be painful. Vaginismus (say: "vag-in- ...

 
 
 
 
221

32 CFR 199.4 - Basic program benefits.  

Science.gov (United States)

...part of an authorized breast reconstruction procedure...reduction of the collateral breast for purposes of ensuring breast symmetry) (F) Panniculectomy...vagina in a biological male who had undergone transsexual...therapy for oral or facial cancer. (2 )...

2010-07-01

222

Laparoscopic Supracervical Hysterectomy  

Medline Plus

Full Text Available ... The cervix is the little organ at the end of the uterus which attaches to the vagina ... insert in the umbilicus and that's where we end up inside the patient's abdomen, which is…I ...

223

C-Section  

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Full Text Available ... and dilated. When the cervix is 10 cm wide, the baby delivery stage starts. This is when the baby moves through the cervix and vagina to the outside world! The path the baby travels through is called ...

224

Vaginal Birth  

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Full Text Available ... or a When the cervix is 10 cm wide, the baby delivery stage starts. This is when the baby moves through the cervix and vagina to the outside world! The path the baby travels through is called ...

225

Dilation and Curettage  

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Full Text Available ... And Curettage Reference Summary Introduction Dilation and curettage, or D&C, is a procedure that is used ... and the possible diseases that can be treated or diagnosed with it. Vagina Uterus Fallopian Tubes Ovaries ...

226

Robotic-Assisted Hysterectomy  

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Full Text Available ... 24:55 Here's the robot being driven in adjacent to the patient. The robot is heavy: it's ... blue ring is placed again through the vagina adjacent to the cervix, and it's what marks our ...

227

Robot-Assisted Gynecologic Oncology Surgery  

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Full Text Available ... difficult to work on because everything is all compressed. So weight itself can be misleading. I'd ... the vagina, because we're going to lose air and we're going to lose our visibility ...

228

Vaginal atresia with transverse septum in a cat  

International Nuclear Information System (INIS)

A six and half-year-old nulliparous mixed breed cat which had the complaints of vomiting, abdominal distention and depression was presented to the Veterinary Teaching Hospital of Osaka Prefecture University. She was suspected of pyometra by clinical signs and tests. By laparotomy, it was clarified that both uterine horns and vagina showed distension by the accumulation of secretions, and the vagina ended blindly leaving a tough connective tissue at the border between cranial and caudal part of the vagina. Postoperative contrast-radiograph of the remaining vagina proved it had no persistence of the hymen. From these findings, the condition was diagnosed as a feline atresia vaginalis with the transverse vaginal septum which is caused by the embryonic failure of canalization of the paramesonephric duct between the end of the Mullerian duct and the urogenital sinus

229

Robotic-Assisted Laparoscopic Sacrocolpopexy for Vaginal Vault Prolapse  

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Full Text Available ... could deviate the vagina anteriorly up towards the synthesis. Thanks very much. And I'm just going ... direction from the camera port, which is the green dot. 00:43:33 ANTHONY G. VISCO, MD: ...

230

Chemotherapy  

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Full Text Available ... can cause changes in hormone levels, decreased blood supply to the penis, and damage to the nerves ... vagina and increased pain with sexual intercourse. Lubricating, water-soluble jelly such as, KY Jelly ™, can help ...

231

Robotic-Assisted Hysterectomy  

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Full Text Available ... beginning of the surgeon's learning curve. Ultimately the goal is to have this be if it's something ... ll be able to get that safely. My goal is to not enter the vagina here, it's ...

232

Ovarian Cancer  

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Full Text Available ... behind the vagina and uterus. Cancer and its Causes The body is made up of very small ... com oc120107 Last reviewed: 05/25/2013 4 Causes The cause of ovarian cancer is still unknown. ...

233

Metronidazole Oral  

Science.gov (United States)

Metronidazole eliminates bacteria and other microorganisms that cause infections of the reproductive system, gastrointestinal tract, skin, vagina, ... Metronidazole comes as a tablet to take by mouth. It is usually taken two or three times ...

234

Robot-Assisted Gynecologic Surgery  

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Full Text Available ... inside the uterine cavity, and then, that green cap wraps around the cervix, and so, it goes ... the vagina. So now, we use t hat cap while we are dissecting from above as a ...

235

Robot-Assisted Gynecologic Oncology Surgery  

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Full Text Available ... deliver that through the vagina without too much difficulty. The uterus is kind of big -- and it's ... in a certain position when we had some difficulty holding it in position. Okay. 00:37:24 ...

236

Robotic-Assisted Laparoscopic Sacrocolpopexy for Vaginal Vault Prolapse  

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Full Text Available ... One would be difficulty dissecting the presacral space, difficulty suturing the mesh to the vagina and to the sacrum, and there's certainly a steep learning curve as you're learning how to perform ...

237

Robotic-Assisted Hysterectomy for Endometrial Cancer  

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Full Text Available ... be a very similar procedure, hopefully with less adhesive disease than we found over on her right ... heat so there is no worry about cautery damage to the vagina. There isn’t significant heat ...

238

HIV and AIDS  

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Full Text Available ... causes a thick, white coating on the mucous membranes of the mouth, tongue, esophagus or vagina. Cryptococcal meningitis causes inflammation of the membranes and fluid around the brain and spinal cord. ...

239

21 CFR 884.5400 - Menstrual cup.  

Science.gov (United States)

...2010-04-01 2010-04-01 false Menstrual cup. 884.5400 Section 884.5400 Food...Gynecological Therapeutic Devices § 884.5400 Menstrual cup. (a) Identification. A menstrual cup is a receptacle placed in the vagina...

2010-04-01

240

[Morphogenesis of vaginal aplasia. Therapeutic deductions].  

Science.gov (United States)

On the basis of the studies of the embryogenesis of the vagina, the authors consider that malformations classically described as being partial aplasia should not be separated from the total absence of the vagina. The important feature is the association of a functioning or non functioning uterus with the absence of the vagina. They believe that it is incorrect to describe the pouch of menstrual retention associated with a functioning uterus as "haematocolpos" and that is not justified to describe the cup-shaped vestibular depression as "hemi-vagina". According to the authors, although vaginal aplasia with a functioning uterus forming a pouch of menstrual retention constitutes an absolute indication for surgery, surgery is not justified in cases of vaginal aplasia with a non functioning uterus. If Frank's method fails in these cases, the patient or the couple should be referred to a sexologist, as women with this anomaly retain a perfect femininity, although unable to conceive. PMID:4059773

Minh, H N; Smadja, A; Belaisch, J

1985-01-01

 
 
 
 
241

Vaginal Birth  

Medline Plus

Full Text Available ... on its way to the vagina. During the first stage of labor, the cervix slowly becomes 10 ... labor start going back to normal during the first hour after birth. Pain Control Some women, especially ...

242

38 CFR Appendix C to Part 4 - Alphabetical Index of Disabilities  

Science.gov (United States)

... And both ovaries, removal7617 Disease or injury7613 Displacement7622 Prolapse7621 Removal7618 Uveitis6000 Vagina, disease or injury7611 Vagotomy7348 Valvular heart disease7000 Varicose veins7120...

2010-07-01

243

Hydrocolpos in dogs: surgical treatment in two cases.  

Science.gov (United States)

Two young female dogs were diagnosed with hydrocolpos as a result of a congenital vaginal obstruction. In one dog, hydrocolpos had led to faecal tenesmus; in the other, the condition was an incidental finding during laparotomy. Diagnostic tests included vaginoscopy, ultrasonography and retrograde vagino-urethrocystography. In both dogs, the obstruction was located at the junction between the caudal vagina and the vaginal vestibule. Anastomosis of the caudal vagina and vestibule through an episiotomy was successful in both cases. PMID:14510330

Viehoff, F W; Sjollema, B E

2003-09-01

244

Vesicovaginal reflux: A case report.  

Science.gov (United States)

Vesicovaginal reflux is a common cause of urinary incontinence in girls. A micturating cystourethrogram, which is the diagnostic investigation of choice, can demonstrate retrograde filling of the vagina during micturition and the complete emptying of the vagina at the end of micturition. Vesicovaginal reflux is a rare cause of gross hydrocolpos occurring without any anatomical obstruction. The condition may be associated with functional voiding disturbances. PMID:19881094

Warade, Monali; Majid, Yameen; Dayananda, L; Gupta, Kanchan

2009-01-01

245

Vesicovaginal reflux: A case report  

Science.gov (United States)

Vesicovaginal reflux is a common cause of urinary incontinence in girls. A micturating cystourethrogram, which is the diagnostic investigation of choice, can demonstrate retrograde filling of the vagina during micturition and the complete emptying of the vagina at the end of micturition. Vesicovaginal reflux is a rare cause of gross hydrocolpos occurring without any anatomical obstruction. The condition may be associated with functional voiding disturbances. PMID:19881094

Warade, Monali; Majid, Yameen; Dayananda, L; Gupta, Kanchan

2009-01-01

246

Vesicovaginal reflux: A case report  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Vesicovaginal reflux is a common cause of urinary incontinence in girls. A micturating cystourethrogram, which is the diagnostic investigation of choice, can demonstrate retrograde filling of the vagina during micturition and the complete emptying of the vagina at the end of micturition. Vesicovaginal reflux is a rare cause of gross hydrocolpos occurring without any anatomical obstruction. The condition may be associated with functional voiding disturbances.

Warade, Monali; Majid, Yameen; Dayananda, L.; Gupta, Kanchan

2009-01-01

247

Escherichia coli Strains from Pregnant Women and Neonates: Intraspecies Genetic Distribution and Prevalence of Virulence Factors  

Digital Repository Infrastructure Vision for European Research (DRIVER)

To determine the extent to which the vagina, endocervix, and amniotic fluid screen the Escherichia coli strains responsible for neonatal infections, we studied the genetic relationships among 105 E. coli strains isolated from all of the ecosystems involved in this infectious process. Twenty-four strains were isolated from the intestinal flora, and 25 strains were isolated from the vaginas of pregnant women. Twenty-seven strains were isolated from the amniotic fluid, blood, and cerebrospinal f...

Watt, Ste?phane; Lanotte, Philippe; Mereghetti, Laurent; Moulin-schouleur, Maryvonne; Picard, Bertrand; Quentin, Roland

2003-01-01

248

Histología uretral y vaginal en algunas hembras de mamíferos / Urethral and vaginal histology in some female mammals  

Scientific Electronic Library Online (English)

Full Text Available SciELO Mexico | Language: Spanish Abstract in spanish El análisis de las características histológicas de la uretra y la vagina en hembras de mamíferos es útil para entender la fisiología y la patología de procesos como la continencia urinaria, la cópula y el parto. En este contexto, las especies más estudiadas en cuanto a la organización tisular de la [...] uretra y vagina son la rata y la coneja. Es necesario estudiar con más detalle la organización tisular de la vagina y uretra en diferentes especies con fines de comparación. Tal información permitiría entender la diversidad funcional y conductual asociada a estos órganos. El presente documento reúne, compara y discute la información existente sobre las características histológicas de la uretra y la vagina en algunas hembras de mamíferos destacando aquellas de la coneja, modelo utilizado por nuestro grupo de investigación para estudiar la fisiología reproductiva y urinaria femenina. Abstract in english The analysis of the histological characteristics of the urethra and the vagina in female mammals is useful in understanding the physiology and pathology of processes such as urinary continence, copulation and delivery. In this regard, the species most studied with respect to the histological organis [...] ation of the urethra and vagina, are the rat and the rabbit. For comparative purposes, it is necessary to study in greater detail the histological organisation of the urethra and vagina in different species. The information gathered could help understand the functional and behavioural diversity associated with these organs. This study gathers, compares and discusses the existing information on the histological characteristics of the urethra and vagina in some mammal females, with emphasis on those of the rabbit, a model used by our research group to study female reproductive and urinary physiology.

J, Rodríguez-Antolín; E, Cuevas; L, Nicolás; V, Fajardo; F, Castelán; M, Martínez-Gómez.

2012-04-01

249

Caracterització de les propietats que fan de lactobacillus el regulador de l'ecosistema vaginal i el protector contra els patògens genito-urinaris  

Digital Repository Infrastructure Vision for European Research (DRIVER)

In the human vagina, the microflora and its ecosystem should be in balance, in order to protect the vagina from colonizations and infections. In this ecosystem, Lactobacillus is the most important microorganism due to their number and activity. Urinary tract infections and vulvovaginal candidiasis are prevalent pathologies in women. In these situations, Lactobacillus has demonstrated to play an important role avoiding vaginal colonization and posterior infection. The basic mechanisms, for whi...

Osset I Lladonosa, Jordi

2003-01-01

250

Continent vesicovaginal fistula.  

Science.gov (United States)

Vesicovaginal fistula is an abnormal communication between the bladder and vagina and represents the most frequent type of fistula in the urinary tract. The most common cause in Brazil is iatrogenic fistula, secondary to histerectomia. Classically these women present continuous urinary leakage from the vagina and absence of micturition, with strong negative impact on their quality of life. We present a case of totally continent vesicovaginal fistula, with a follow-up of 11 years with no complications. PMID:23579756

Toledo, Luís Gustavo Morato de; Santos, Victor Espinheira; Maron, Paulo Eduardo Gourlat; Vedovato, Bruno César; Fucs, Moacyr; Perez, Marjo Deninson Cardenuto

2013-01-01

251

Histología uretral y vaginal en algunas hembras de mamíferos / Urethral and vaginal histology in some female mammals  

Scientific Electronic Library Online (English)

Full Text Available SciELO Mexico | Language: Spanish Abstract in spanish El análisis de las características histológicas de la uretra y la vagina en hembras de mamíferos es útil para entender la fisiología y la patología de procesos como la continencia urinaria, la cópula y el parto. En este contexto, las especies más estudiadas en cuanto a la organización tisular de la [...] uretra y vagina son la rata y la coneja. Es necesario estudiar con más detalle la organización tisular de la vagina y uretra en diferentes especies con fines de comparación. Tal información permitiría entender la diversidad funcional y conductual asociada a estos órganos. El presente documento reúne, compara y discute la información existente sobre las características histológicas de la uretra y la vagina en algunas hembras de mamíferos destacando aquellas de la coneja, modelo utilizado por nuestro grupo de investigación para estudiar la fisiología reproductiva y urinaria femenina. Abstract in english The analysis of the histological characteristics of the urethra and the vagina in female mammals is useful in understanding the physiology and pathology of processes such as urinary continence, copulation and delivery. In this regard, the species most studied with respect to the histological organis [...] ation of the urethra and vagina, are the rat and the rabbit. For comparative purposes, it is necessary to study in greater detail the histological organisation of the urethra and vagina in different species. The information gathered could help understand the functional and behavioural diversity associated with these organs. This study gathers, compares and discusses the existing information on the histological characteristics of the urethra and vagina in some mammal females, with emphasis on those of the rabbit, a model used by our research group to study female reproductive and urinary physiology.

J, Rodríguez-Antolín; E, Cuevas; L, Nicolás; V, Fajardo; F, Castelán; M, Martínez-Gómez.

252

Vaginal position and length in the bitch: relationship to spaying and urinary incontinence  

International Nuclear Information System (INIS)

A study was undertaken to determine if the vagina might be a suitable site for the measurement of intra-abdominal pressure during cystometry in the bitch, The position of the cranial vagina and vaginal length were measured radiographically and the effects of spaying and urinary Incontinence on these variables were evaluated in 30 continent and 30 incontinent bitches. The study used retrograde vaginourethrograms which had been obtained from animals used in a previous study, The cranial vagina was intra-abdominal on 36 of the vaginourethrograms, being least commonly intra-abdominal in incontinent bitches (11/30), Vaginal position was related linearly to vaginal length and continence status (P<0.01), while its length was related to bodyweight(P<0.01). Allowing for bodyweight, neutered animals had significantly shorter vaginas than entire bitches (P<0.01). Measurement of intra-abdominal pressure with concomitant measurement of intravesical pressure is essential if accurate assessment of detrusor pressure is to be determined during cystometry, The vagina is unlikely to be a useful location from which to measure intra-abdominal pressure since any pressure-measuring catheter inserted into it may fall outside the abdominal pressure zone. This is particularly true of neutered and/or incontinent bitches, the groups in which urodynamic investigations of urinary incontinence are most frequently indicated

253

Results of radiotherapy for primary vaginal cancer  

International Nuclear Information System (INIS)

Background: Cancer of the vagina is the least frequent primary malignant tumor of the female genital tract except carcinoma of the fallopian tube. Radiation therapy is the preferred treatment in most cases. Patients and Method: Between 1965 and 1991, 39 patients (median age 66 years) with primary carcinoma of the vagina were treated with radiation therapy at our clinic. The mean observation period was 37 months. Classification according to the FIGO yielded a stage I in 43%, stage II in 24%, stage III in 22% and stage IV in 11%. Histological differentiation resulted in 35 squamous cell carcinomas and 4 adenocarcinomas. In 69%, the tumor was found on the posterior or lateral wall of the vagina, in 43% it arose from the upper third of the vagina. Standard therapy consisted of combined brachy- and teletherapy. Most of the brachytherapy applications were performed with a radium source. Results: Median survival was 37 months, calculated according to the Kaplan-Meier method. The 5-year actuarial survival rate for all stages was 41% (stage I: 62%, stage II: 44%, stage III: 25%). Sixty-eight percent of all patients achieved a complete remission, 19% a partial response. Significant prognostic factors were stage of disease and histological grading. Conclusion: Our results demonstrate the value of radiation therapy for the treatment of primary carcinoma of the vagina. Combined treatment with both external beam radiation and brachytherapy should be preferred. (orig.)should be preferred. (orig.)

254

Anatomia e histologia do conduto genital feminino de Pomacea canaliculata (Lamarck, 1822) (Mollusca, Gastropoda, Pilidae)  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese [...] Abstract in english In this paper the authors give an anatomical and histological analysis of the genital duct in mature and immature females of Pomacea canaliculata (Lamarck, 1822). Anatomically, the vagina has an equal dimension in its extension, varying in form and volume, according to the maturation period. In the [...] immaturity, it has a smaller diameter and volume. In the maturity, the vagina increases in volume, having the aspect of a tumescent organ, and in certain specimens shows an albuminous pink thread in its lumen. Histologically, the calcigenic activity of the gland is evidentiated by the presence of an amorphous and basophilic mass, without nuclear material. This material has a fragmented aspect in the vagina lumen that reacts positively in van Kossa's coloured preparations for calcareous salts.

Eliana de Fátima Marques de, Mesquita; Arnaldo Campos dos Santos, Coelho; Jefferson Andrade dos, Santos.

255

Sobre uma nova espécie do gênero Acanthocolpus Lühe, 1906 / On a new specie under Acanthocolpus Lühe, 1906  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese Os autores, na presente nota, propõem Acanthocolpus brasiliensis sp. n. sendo este gênero pela primeira vez referido no Brasil. A espécie aqui descrita difere das demais do gênero pela ausência de espinhos na vagina e no ducto hermafrodita e pela presença de vitelinos em quase toda extensão da metad [...] e posterior do corpo. Abstract in english In this paper the authors propose a new specie under Acanthocolpus Lühe, 1906 also reafirms this genus for the first time in Brasil. Acanthocolpus brasiliensis sp. n. differs from the other species of the genus by presenting folicular vitellaria in almost the hole area of the posterior part of the b [...] ody, by the absence of spines in vagina and in ejaculatory duct. A. brasiliensis sp. n. is similar to A. orientalis Srivastava, 1939, which differs also by the size of the body, cirrus sac and vagina.

Berenice M. M., Fernandes; Santiago V. de, Souza.

256

Expression of Toll-like receptors (TLRs) and TLR4 response to lipopolysaccharide in hen oviduct.  

Science.gov (United States)

The aim of this study was to determine the types of Toll-like receptors (TLRs) expressed in the hen oviduct, and to confirm that vaginal tissue expressing TLR4 responds to lipopolysaccharide (LPS). Healthy laying hens were intravenously or intravaginally injected with LPS, PBS or untreated. The expression pattern of TLRs in the whole oviduct and the effects of LPS on TLR4 and IL-1beta in the vagina were examined by semi-quantitative RT-PCR. The population of cells containing TLR4 protein was examined by immunohistochemistry. The expression of 6 types of TLRs (TLR1 type 2, TLR2, TLR3, TLR4, TLR5 and TLR7) were identified in all segments of the oviduct. The densities of PCR products for each TLR showed a tendency to be greater in the vagina than in the magnum and isthmus. Immunoreactive TLR4 was localized in the epithelial cells and leukocytes in the isthmus, uterus and vagina. Intravenous injection with LPS increased the TLR4 expression and the population of TLR4-immunopositive cells in the vagina. Intravaginal injection with LPS resulted in the increase of leukocytes in the mucosal tissues in association with an increase of TLR4 expression and TLR4-immunopositive cells in the vagina. The IL-1beta expression was also enhanced in a similar manner to that of TLR4. These results suggest that the hen oviduct expresses at least 6 types of TLRs including TLR4 with a greater expression in the vagina. Vaginal tissue expressing TLR4 responds to LPS and in turn upregulate cellular functions to synthesize cytokines. Such expression and functions of TLRs may play an essential role in oviductal innate immunity for host defense. PMID:19046776

Ozoe, Atsufumi; Isobe, Naoki; Yoshimura, Yukinori

2009-02-15

257

The impact of radiotherapy for carcinoma of the cervix on sexual function assessed using the LENT SOMA scales  

International Nuclear Information System (INIS)

Background and purpose: As there are few studies examining the impact of radiotherapy on sexuality, we assessed the effect of radiotherapy for carcinoma of the cervix on sexual health and the ability of the LENT system to assess sexual function. Materials and methods: Using the vagina and sexual dysfunction scales of the LENT SOMA scales, subjective scores were measured prospectively before initiation of radiotherapy for 89 women, and at the following times after the start of treatment: 21, 70, 200, 400, 600 and 800 days. Results: There was considerable variation in pre-radiotherapy scores that was not related to disease stage (P=0.054), but was related to patient age (P=0.037, for the average vagina scores and P=0.039 for the maximum vagina scores) The scores were influenced by prior surgery (P<0.0005 for maximum and average vagina scores, P=0.042 average and 0.017 maximum sexual dysfunction scores). For 48 patients for whom data were available at the first three time points, the vagina scores decreased significantly by 70 days compared to pre-radiotherapy scores, but not for sexual dysfunction. There was heterogeneity in the pattern of changes of scores over time: for some women there was no change in vagina subsection score, some increased, and some decreased. Conclusions: The work has shown variation both in pre-treatment sexual function and in the pattern of changes seen following radiotherapy. Our questionnaire proved useful to score subjective sexual and vaginal problems as given in the LENT subjective scales. Further study is needed to assess the effectiveness of the scales in assessing late effects

258

[Imperforate hymen can cause abdominal pain and primary amenorrhoea].  

Science.gov (United States)

Imperforate hymen (HI) is a rare condition caused by the hymen covering the entire opening of the vagina. This prevents the menstruation blood from being drained and the blood fills up the vagina and later the uterus and Fallopian tubes. The produced strain on these organs causes cyclic pain in the lower abdomen. We present two cases where two adolescent girls were diagnosed with HI. It is important to remember HI as a differential diagnosis in young girls with amenorrhoea and lower abdominal pain. In both cases a hymenectomy was performed and the patients recovered afterwards. PMID:23697568

Nielsen, Vibeke; Vyrdal, Christian

2013-05-20

259

Síndrome de Morris / Morris Syndrome  

Scientific Electronic Library Online (English)

Full Text Available SciELO Cuba | Language: Spanish Abstract in spanish Introducción: el síndrome de resistencia completa a los andrógenos, feminización testicular o síndrome de Morris, puede presentarse en uno de cada 20 000 a 64 000 recién nacidos varones. Objetivo: presentar un caso con genotipo masculino y fenotipo femenino dado por desarrollo mamario, con genitales [...] externos femeninos con hipoplasia de los labios mayores y menores y la vagina muy corta que termina en un fondo de saco ciego. Métodos: se valora en la consulta a una paciente adolescente de 19 años de edad con amenorrea primaria y contacto sexual insatisfactorio (imposibilidad de penetración). Resultados: se comprueba al examen vagina rudimentaria de unos dos centímetros y escaso desarrollo de genitales externos. En los exámenes complementarios se comprueban cifras de testosterona y LH aumentadas, así como el estradiol disminuido y un cariotipo 46 XY por lo que se sospecha síndrome de Morris y se planifica intervención quirúrgica combinada en un tiempo (vaginal y abdominal) donde se realiza anexectomía total derecha por video laparoscopia y reconstrucción de vagina por técnica de Williams. Posoperatorio satisfactorio y seguimiento ulterior por consulta donde se comprueba vagina funcional y estabilidad emocional de la paciente. Conclusiones: el estudio anatomo-patológico comprueba la existencia de ovario y testículo en la muestra quirúrgica lo que confirma el diagnóstico de síndrome de Morris o de resistencia completa a los andrógenos. Abstract in english Introduction:the syndrome of complete androgen resistance, testicular feminization or Morris syndrome may occur in one in 20 000 to 64 000 of male newborns. Objective: to present a case with male genotype and female phenotype given by breast development, female external genitalia with hypoplasia of [...] the labia and very short vagina ending in a blind pouch Methods: a 19 year- old female patient is assisted in consultation due primary amenorrhea and unsatisfactory sexual contact (impossibility of penetration). Results: at examination, we found a rudimentary vagina of about two inches and underdeveloped external genitalia. The exams confirmed increased LH and testosterone levels and decreased estradiol. It is also found a 46 XY karyotype, so Morris syndrome is suspected. Combined surgery is planned for the vagina and abdomen. Total videolaparoscopy right adnexectomy and vaginal reconstruction by technique of Williams are performed. We had satisfactory postoperative and subsequent follow-up consultation where functional vagina and emotional stability of the patient were checked. Conclusions: the pathological study verifies the existence of ovary and testis in the surgical specimen confirming the diagnosis of Morris syndrome or complete androgen resistance.

Julio Aurelio, Borrego López; Joel Alejandro, Varona Sánchez; Georgina, Areces Delgado; Luis Ernesto, Formoso Martín.

2012-09-01

260

Acesso sagital transretal anterior (ASTRA) para vaginoplastia após complicação de anoretoplastia sagital posterior / Anterior sagittal transrectal approach (ASTRA) for vaginoplasty after complications of posterior sagittal anorectoplasty  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese A exposição transperineal de altas vaginas é limitada. Essas limitações podem ser contornadas usando ASTRA (anterior sagital transrectal approach). Relatamos o uso desta estratégia cirúrgica para o tratamento de um caso de atresia vaginal adquirida, após anorretoplastia posterior, em caso de malform [...] ação anorretal. Abstract in english Transperineal exposure of the high portion of the vagina is limited. These limitations can be circumvented using ASTRA (anterior sagittal transrectal approach). We report the use of this surgical strategy for the treatment of a case of acquired vaginal atresia after posterior anorectoplasty due to a [...] norectal malformation.

Lisieux Eyer de, Jesus; Laura, Helman; Samuel, Dekermacher; Raquel L., Bernardo; Cruz Delia M., Martinez.

 
 
 
 
261

Síndrome de Morris / Morris Syndrome  

Scientific Electronic Library Online (English)

Full Text Available SciELO Cuba | Language: Spanish Abstract in spanish Introducción: el síndrome de resistencia completa a los andrógenos, feminización testicular o síndrome de Morris, puede presentarse en uno de cada 20 000 a 64 000 recién nacidos varones. Objetivo: presentar un caso con genotipo masculino y fenotipo femenino dado por desarrollo mamario, con genitales [...] externos femeninos con hipoplasia de los labios mayores y menores y la vagina muy corta que termina en un fondo de saco ciego. Métodos: se valora en la consulta a una paciente adolescente de 19 años de edad con amenorrea primaria y contacto sexual insatisfactorio (imposibilidad de penetración). Resultados: se comprueba al examen vagina rudimentaria de unos dos centímetros y escaso desarrollo de genitales externos. En los exámenes complementarios se comprueban cifras de testosterona y LH aumentadas, así como el estradiol disminuido y un cariotipo 46 XY por lo que se sospecha síndrome de Morris y se planifica intervención quirúrgica combinada en un tiempo (vaginal y abdominal) donde se realiza anexectomía total derecha por video laparoscopia y reconstrucción de vagina por técnica de Williams. Posoperatorio satisfactorio y seguimiento ulterior por consulta donde se comprueba vagina funcional y estabilidad emocional de la paciente. Conclusiones: el estudio anatomo-patológico comprueba la existencia de ovario y testículo en la muestra quirúrgica lo que confirma el diagnóstico de síndrome de Morris o de resistencia completa a los andrógenos. Abstract in english Introduction:the syndrome of complete androgen resistance, testicular feminization or Morris syndrome may occur in one in 20 000 to 64 000 of male newborns. Objective: to present a case with male genotype and female phenotype given by breast development, female external genitalia with hypoplasia of [...] the labia and very short vagina ending in a blind pouch Methods: a 19 year- old female patient is assisted in consultation due primary amenorrhea and unsatisfactory sexual contact (impossibility of penetration). Results: at examination, we found a rudimentary vagina of about two inches and underdeveloped external genitalia. The exams confirmed increased LH and testosterone levels and decreased estradiol. It is also found a 46 XY karyotype, so Morris syndrome is suspected. Combined surgery is planned for the vagina and abdomen. Total videolaparoscopy right adnexectomy and vaginal reconstruction by technique of Williams are performed. We had satisfactory postoperative and subsequent follow-up consultation where functional vagina and emotional stability of the patient were checked. Conclusions: the pathological study verifies the existence of ovary and testis in the surgical specimen confirming the diagnosis of Morris syndrome or complete androgen resistance.

Julio Aurelio, Borrego López; Joel Alejandro, Varona Sánchez; Georgina, Areces Delgado; Luis Ernesto, Formoso Martín.

262

Use of Bakri Balloon for Treatment of Persistent Hematocolpos After a LeFort Colpocleisis: A Case Report.  

Science.gov (United States)

LeFort colpocleisis is a simple and effective procedure for pelvic organ prolapse in women who no longer wish to preserve coital function. If the vaginal channels created during this procedure are not large enough, blood or pus may collect within the uterus or proximal vagina. Hematocolpos, accumulation of blood in apical vagina, may be difficult to manage especially when a patient is frail and has medical comorbidities. Here, we present a case of LeFort colpocleisis in which excessive anticoagulation led to an infected hematocolpos and persistent bleeding. This was successfully managed with a Bakri balloon via a vaginal channel without recurrence of her prolapse. PMID:25181384

Yuksel, Beril; Harmanli, Oz; Jones, Keisha A

2014-01-01

263

Vaginal Birth  

Medline Plus

Full Text Available ... when the second stage of labor begins. Stage 2 The second stage of labor starts when the baby goes through the widened cervix, through the vagina to the outside world! This is the when the mother pushes with each contraction. This document is for informational purposes and is not intended ...

264

Endometriosis  

Medline Plus

Full Text Available ... the outside of the body through the vagina. Diagnosis To diagnose endometriosis, the gynecologist must take a ... may be necessary to make sure that other diseases, such as infections or kidney problems, are not the reason for the symptoms. ...

265

Disorders of the Vulva  

Science.gov (United States)

... a group of related viruses, some of which cause genital warts and some of which are linked to cervical changes and cancer of the cervix, vulva, vagina, penis, anus, and throat. Inflammation: Pain, swelling, redness, and irritation of tissues in the ...

266

Image based brachytherapy planning with special reference to gynaecological cancers  

International Nuclear Information System (INIS)

Cervical cancer is the most common cancer among women in India and one of the most frequent malignancies in Europe and in North America. In addition endometrium, vagina and vulva cancer are treated with brachytherapy. Especially for locally advanced cervix cancer the integration of image based brachytherapy planning into clinical routine is becoming a new standard for the future

267

CUERPO EXTRAÑO INTRAVAGINAL SECUNDARIO A MIGRACIÓN DE AGUJA DE OSTEOSÍNTESIS DE CADERA  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Se presenta caso clínico de migración de aguja de fijación de artroplastia de cadera a vagina en mujer embarazadaWe report a case of an intravaginal foreign body due to migration of needle hip fixation from hip arthroplasty in a pregnant woman

Ernesto Perucca P; Marcelo Reyes S; María José Diez C; Marcela Veloz T

2007-01-01

268

Ovarian Cancer  

Medline Plus

Full Text Available ... patient. Surgery is usually necessary to remove the cancer. During surgery, all the female reproductive organs, except for the vagina, may be taken out to try to ensure that no cancer is left behind. This operation is known as ...

269

Amniocentesis  

Medline Plus

Full Text Available ... It is not available in many places. This test takes a sample of placenta tissue through the vagina or the abdomen. CVS can be done 6 weeks earlier than amniocentesis, around 10 to 12 weeks ... A new blood test and ultrasound is now available to check for ...

270

Ovarian Cancer  

Medline Plus

Full Text Available Ovarian Cancer Introduction Ovarian cancer is fairly rare. Ovarian cancer usually occurs in women who are over 50 years old and it may ... This reference summary will help you understand how ovarian cancer is detected and treated. Anatomy Vagina Uterus ...

271

Abdominal pregnancy with a full term live fetus: Case report  

Directory of Open Access Journals (Sweden)

Full Text Available This is a case report of an abdominal pregnancy that was carried to term with live fetus. Illiteracy, poverty and lack of antenatal care had resulted in her late presentation. Bleeding per vagina, persistence abdominal pain, weight loss and pallor were the main clinical features. She had laparotomy and delivery of a live fetus.

Isah A

2008-12-01

272

Cervical Cancer Stage IA  

Science.gov (United States)

... IA Description: Stage IA1 and IA2 cervical cancer; drawing shows a cross-section of the cervix and vagina. An inset shows cancer in the cervix that is up to 5 mm deep, but not more than 7 mm wide. A ...

273

Accessory Reproductive Organs Dimension of Two Species of Giant African Land Snails Archachatina marginata and Achatina achatina at Three Liveweight Ranges  

Directory of Open Access Journals (Sweden)

Full Text Available A comparative study of the reproductive tract of two species of Giant African Land Snails, Archachatina marginata and Achatina achatina was carried out. Three groups of snails weighing 80-100,101-150 and 151-250 g were used in a 2x3 factorial design, with 5 replicates, involving a total of 30 snails. Dimensions and weights of retractor penile muscle, vas deferens, penis, vagina, oviduct, spermotheca, common duct, albumen gland and little hermaphrodite duct were taken. Results showed that Archachatina marginata had longer, wider and heavier accessory sex organs compared to Achatina achatina except for vas deferens width, vagina length, vagina width, and vagina weight, which were otherwise. Dimensions and weights of the accessory organs increased consistently with liveweight, except for retractor penile muscle width, which had attained maximum size by a body weight of 101-150 g. It can be concluded that Archachatina marginata had better reproductive tract dimension compared to their counterpart (Achatina achatina. It is however recommended that liveweight group 151-250 g be considered as group of choice when considering anatomical display of reproductive parts for demonstrative purpose and testing of manipulating tools for reproductive strategies in both species.

J. A. Abiona

2012-02-01

274

Pyelonephritis and Bacteremia from Lactobacillus delbrueckii  

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Lactobacilli are normal colonizers of the oropharynx, gastrointestinal tract, and vagina. Infection is rare, but has been reported in individuals with predisposing conditions. Here we describe the case of a woman with pyelonephritis and bacteremia in which Lactobacillus delbrueckii was determined to be the causative agent.

Duprey, Kevin M.; Leon McCrea; Rabinowitch, Bonnie L.; Azad, Kamran N.

2012-01-01

275

Ovarian Cancer  

Medline Plus

Full Text Available Ovarian Cancer Introduction Ovarian cancer is fairly rare. Ovarian cancer usually occurs in women who are over 50 years old and it may sometimes ... This reference summary will help you understand how ovarian cancer is detected and treated. Anatomy Vagina Uterus Fallopian ...

276

Robotic-Assisted Hysterectomy  

Medline Plus

Full Text Available ... you'll see is you'll see a blue ring. There it is. And that blue ring is placed again through the vagina adjacent ... on the right and left. And then that blue ring, which you'll see in a second, ...

277

Limnomermis subtropicalis n. sp. (Nematoda:Mermithidae a Parasite of Larvae of Simulium orbitale Lutz (Diptera:Simuliidae in Argentina  

Directory of Open Access Journals (Sweden)

Full Text Available Limnomermis subtropicalis n. sp. (Nematoda: Mermithidae a parasite of Simulium orbitale Lutz (Diptera: Simuliidae found in Argentina is described and illustrated. This species is characterized by having medium sized amphids, pocket-shaped, medium sized vagina, sculptured spicule, and by having 9 preanal, 7 postanal papillae in the ventral row, and 12 papillae in the lateral rows

Villalobos L Cristina de

1997-01-01

278

Mayer-Rokitansky-Kuster-Hauser Syndrome.  

Science.gov (United States)

Mayer-Rokitansky-Küster-Hauser Syndrome is a congenital malformation in which there is failure of the Müllerian ducts to develop resulting in absent uterus and fallopian tubes and variable malformations of the vagina. Ultrasonography reveals absence of uterus with normally visualised ovaries. PMID:25098098

Adil, Ruqqayia; Qayyum, Adil

2013-01-01

279

Stages of Labor  

Science.gov (United States)

... cervix is the opening to the uterus that sits at the top of the vagina. In order to have fetal-scalp blood sampling, your cervix must be dilated enough that your provider can reach your baby’s head. The test may remind you of a pelvic exam. It ...

280

40 CFR 79.63 - Fertility assessment/teratology.  

Science.gov (United States)

...effects on reproductive development which would only be...for conception and the development of offspring. The...general condition of the cells present in the vagina...presence of sperm in the cell smear. On pregnancy...contents examined for embryonic or fetal...

2010-07-01

 
 
 
 
281

Tumors of female genitals  

International Nuclear Information System (INIS)

International classification of stages of cancer of the neck of the uterus, the body of the womb, vagina, ovary, vulva, is presented. Methods of radiotherapy: distant radiation, intracavitary radiation concomitant radiotherapy in preoperative and postoperative period with indication of radiation doses and dose distributions are described

282

Robot-Assisted Gynecologic Surgery  

Medline Plus

Full Text Available ... Here’s the urinary bladder. We’ve got the uterus, right here, and we’ve got both ovaries ... some of that anatomy, the ovaries. Here’s the uterus. Connected to the uterus is the vagina, which ...

283

Robotic-Assisted Hysterectomy for Endometrial Cancer  

Medline Plus

Full Text Available ... of disposable instruments. There are no other energy sources or instruments that are use. You’ll see if we have time, when we sew on the vagina we’re using just a traditional suture material. There’s no special type of suture or needle required, so we save ...

284

Pap Smear  

Medline Plus

Full Text Available ... X-Plain.com og020106 Last reviewed: 10/01/2012 1 The female reproductive organs include: • The vagina • ... X-Plain.com og020106 Last reviewed: 10/01/2012 2 Cervical cancer usually develops gradually. At first, ...

285

Lactobacillus delbrueckii as the Cause of Urinary Tract Infection?  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Lactobacilli are part of the normal bacterial flora of the vagina and are typically considered contaminants when cultured from urine specimens of female patients. Here we describe the case of a female patient with chronic pyuria and urinary tract symptoms in which Lactobacillus delbrueckii was determined to be the causative microorganism.

Darbro, Benjamin W.; Petroelje, Brian K.; Doern, Gary V.

2009-01-01

286

Ultrasound diagnosis of pyocolpos  

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Full Text Available Cystic dilatation of vagina due to genital tract obstruction is rare. the cause of obstruction can be imperforate hymen, transverse vaginal septum and vaginal atresia. We pictographically demonstrate a case of 45 days old infant presenting with abdomino-pelvic cystic mass

Gandage S

2007-01-01

287

Diaphragm  

Science.gov (United States)

... or cause an allergic reaction. Strong odors or vaginal discharge may appear if the diaphragm is left in too long. The rubber or ... pelvic exam the doctor will measure a girl's vagina and then determine which size of diaphragm is right for her. The doctor or nurse ...

288

40 CFR 798.4700 - Reproduction and fertility effects.  

Science.gov (United States)

...8 weeks old. For both sexes, dosing shall be continued...shall be placed with a single male from the same dose...prevents having 4 of each sex per litter, partial...stillbirths, live births, sex, and the presence of...Vagina; uterus; ovaries; testes; epididymides;...

2010-07-01

289

Condiloma Acuminado  

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Full Text Available El Condilomas Acuminado es una enfermedadcausada por el Virus Papiloma Humano.Se caracteriza por el crecimiento de verrugas blandas en los genitales o en la regiónanal, o sea que crece entre los muslos y la parte interna de las nalgas, en el pene o en la vagina.

Juan Carlos Céspedes Escobar

2011-06-01

290

Robot-Assisted Gynecologic Oncology Surgery  

Medline Plus

Full Text Available ... the ureter as it enters vessels bifurcate. What I'm going to do now is isolate the infundibular pelvic ... trying to separate the vagina from the uterus. I'm going to -- Lisa, can we not get that over ...

291

C-Section  

Medline Plus

Full Text Available ... the baby floats in a special fluid called amniotic fluid. Both the baby and amniotic fluid are in a bag called the “amniotic sac.” ... amniotic sac opens before the actual delivery and amniotic fluid seeps out through the vagina. When this happens, ...

292

Vaginal Birth  

Medline Plus

Full Text Available ... the baby is in a special fluid called amniotic fluid. The baby and amniotic fluid are in a bag called the “amniotic sac” ... times the amniotic sac opens up and the amniotic fluid seeps out through the vagina. When this happens, ...

293

Anterior sagittal transrectal approach (ASTRA) for vaginoplasty after complications of posterior sagittal anorectoplasty.  

Science.gov (United States)

Transperineal exposure of the high portion of the vagina is limited. These limitations can be circumvented using ASTRA (anterior sagittal transrectal approach). We report the use of this surgical strategy for the treatment of a case of acquired vaginal atresia after posterior anorectoplasty due to anorectal malformation. PMID:23912372

de Jesus, Lisieux Eyer; Helman, Laura; Dekermacher, Samuel; Bernardo, Raquel L; Martinez, Cruz Delia M

2013-01-01

294

Vaginal Birth  

Medline Plus

Full Text Available ... During pregnancy, the baby is in a special fluid called amniotic fluid. The baby and amniotic fluid are in a bag called the “amniotic sac” ... the amniotic sac opens up and the amniotic fluid seeps out through the vagina. When this happens, ...

295

C-Section  

Medline Plus

Full Text Available ... During pregnancy, the baby floats in a special fluid called amniotic fluid. Both the baby and amniotic fluid are in a bag called the “amniotic sac.” ... sac opens before the actual delivery and amniotic fluid seeps out through the vagina. When this happens, ...

296

32 CFR 199.4 - Basic program benefits.  

Science.gov (United States)

...be repair of facial scarring resulting from dermabrasion for acne or repair of a prolapsed vagina in a biological male who had...gastric banding. (KK) Calcium EAP/calcium orotate and selenium (also known as Nieper therapy)—Involves inpatient...

2010-07-01

297

C-Section  

Medline Plus

Full Text Available ... between the urinary bladder and the rectum. 1 2 3 4 4 5 5 The female reproductive organs include: 1. The vagina 2. The cervix 3. The uterus 4. The Fallopian tubes 5. The ovaries When an ovary releases an egg, ...

298

Robot-Assisted Gynecologic Oncology Surgery  

Medline Plus

Full Text Available ... not working. Put the balloon back in the vagina and we'll retrieve the lymph nodes from up top or something, because I don' ... finish up here. We're closing up the vaginal cuff. We'll secure that. We're going to retrieve the lymph node bundles that we dissected, and then basically we' ...

299

Aggressive angiomyxoma.  

Science.gov (United States)

Myxoid tumors are a heterogeneous group of lesions characterized by a marked abundance of extra cellular mucoid (myxoid) matrix.[1] The term aggressive emphasizes the often infiltrative nature of the tumor and its frequent association with recurrence.[2] A case of aggressive angiomyxoma arising from the vagina in a 55-year-old woman is reported for its rarity. PMID:24860748

Padmavathy, L; Rao, L Lakshmana; Lakshmi, M Dhana; Sylvester, N

2014-04-01

300

CUERPO EXTRAÑO INTRAVAGINAL SECUNDARIO A MIGRACIÓN DE AGUJA DE OSTEOSÍNTESIS DE CADERA  

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Full Text Available Se presenta caso clínico de migración de aguja de fijación de artroplastia de cadera a vagina en mujer embarazadaWe report a case of an intravaginal foreign body due to migration of needle hip fixation from hip arthroplasty in a pregnant woman

Ernesto Perucca P

2007-01-01

 
 
 
 
301

CUERPO EXTRAÑO INTRAVAGINAL SECUNDARIO A MIGRACIÓN DE AGUJA DE OSTEOSÍNTESIS DE CADERA  

Scientific Electronic Library Online (English)

Full Text Available SciELO Chile | Language: Spanish Abstract in spanish Se presenta caso clínico de migración de aguja de fijación de artroplastia de cadera a vagina en mujer embarazada [...] Abstract in english We report a case of an intravaginal foreign body due to migration of needle hip fixation from hip arthroplasty in a pregnant woman [...

Ernesto, Perucca P; Marcelo, Reyes S; María José, Diez C; Marcela, Veloz T.

302

C-Section  

Medline Plus

Full Text Available ... baby’s blood. The mother’s blood also picks up waste from the baby’s blood. The baby’s blood travels ... the vagina. When this happens, we say the “water broke.” Labor can start when the water breaks. ...

303

Vaginal Birth  

Medline Plus

Full Text Available ... through the placenta. The mother’s blood also removes waste from the baby’s blood through the placenta. The ... vagina. When this happens, we say the mother’s “water broke.” Labor should start if the water breaks. ...

304

Oxytocin determination by radioimmunoassay in cattle. 2  

International Nuclear Information System (INIS)

Oxytocin concentration in jugular vein blood was measured radioimmunologically with a detection limit of 3 pg/ml plasma in male and female cattle. Five bulls were tested; during mating a cow in oestrus with intromission and ejaculation, during mounting a dummy or another bull with ejaculation into an artificial vagina or during false mounts. No increase in oxytocin concentrations could be observed, but stimulation with an electro-ejaculator caused an increase ranging from 5-84 pg/ml after a latent period of 3-5 min. A similar response was observed in two cows following the same procedure. The contact with a bull, false mount or mating with intromission and ejaculation was not followed by a measurable oxytocin release in 5 test cows. The following stimulation techniques, massage of vulva and clitoris, massage of cervix and uterus per rectum, artificial insemination, introduction of a speculum into the vagina or insufflation of air into the vagina were performed with 5 cows and 5 heifers. Insufflation of air into the vagina was the most effective stimulus, eleciting an oxytocin release up to 588 pg/ml. All 5 heiers responded positively, as well as 4 cows in oestrus. The other manipulations cuased an oxytocin response mainly in heifers (whether in oestrus or dioestrus), whereas only one cow in oestrus responded with an oxytocin release. In general, oxytocin concentrations increase about 30-90 s after the start of the stimulus. (author)uthor)

305

Urogenital tumors  

Energy Technology Data Exchange (ETDEWEB)

An overview is provided for veterinary care of urogenital tumors in companion animals, especially the dog. Neoplasms discussed include tumors of the kidney, urinary bladder, prostate, testis, ovary, vagina, vulva and the canine transmissible venereal tumor. Topics addressed include description, diagnosis and treatment.

Weller, R.E.

1994-03-01

306

Robotic-Assisted Hysterectomy  

Medline Plus

Full Text Available ... if in fact you find adhesions to the anterior and lateral abdominal wall after placement of the scope?" Typically when performing ... Typically in a 30-year-old woman with fibroids, the risk of actually ... or ability to deliver the uterus through the vagina, could be used so that ...

307

Comparison of molecular abnormalities in vulvar and vaginal melanomas.  

Science.gov (United States)

Malignant melanoma of the vulva and vagina is relatively uncommon and accounts for NRAS, and KIT mutations by PCR and DNA sequencing as well as for KIT amplifications by fluorescence in situ hybridization. None of the cases contained BRAF mutations. NRAS mutations and KIT amplifications were detected in similar frequency (?12%) in tumors of the vulva and vagina. In contrast, KIT mutations were present in 18% of primary melanomas of the vulva, but in none of the tumors arising in the vagina. Moderate or strong KIT protein expression was detected in 30 cases, including all tumors with KIT mutations and 6 of the 7 with KIT amplifications. In conclusion, BRAF mutations are virtually absent in melanomas originating from the vulva or vagina, whereas NRAS mutations and KIT amplifications occur in both locations. KIT mutations appear to be specific for melanomas of the vulva, suggesting that in spite of the anatomic proximity, the development of vulvar and vaginal melanomas involves different molecular alterations which may be targeted by novel treatment approaches. PMID:24603591

Aulmann, Sebastian; Sinn, Hans P; Penzel, Roland; Gilks, C Blake; Schott, Sarah; Hassel, Jessica C; Schmidt, Dietmar; Kommoss, Friedrich; Schirmacher, Peter; Kommoss, Stefan

2014-10-01

308

Vaginal Birth  

Medline Plus

Full Text Available ... vagina. When this happens, we say the mother’s “water broke.” Labor should start if the water breaks. You should contact your doctor or midwife as soon as the water breaks. The doctor may need to induce labor ...

309

Virulence Factors of Escherichia coli Isolated From Female Reproductive Tract Infections and Neonatal Sepsis  

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Full Text Available Objective: The presence of enterobacteria such as Escherichia coli in the vagina of normal women is not synonymous with infection. However, vaginal E. coli may also cause symptomatic infections. We examined bacterial virulenceproperties that may promote symptomatic female reproductive tract infections (RTI and neonatal sepsis.

Richard A. Hull

2001-01-01

310

Fístula vesicovaginal continente / Continent vesicovaginal fistula  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: Portuguese Abstract in portuguese A fístula vesicovaginal é uma comunicação anormal entre a bexiga e a vagina, sendo o tipo mais comum de fístula do trato urinário. A causa mais frequente no Brasil é a iatrogênica, secundária à histerectomia. Classicamente, as mulheres nessa condição, apresentam perda urinária contínua pela vagina e [...] ausência de micção, com forte impacto negativo na qualidade de vida. Apresentamos um caso de fístula vesicovaginal totalmente continente, com seguimento de 11 anos, sem complicações. Abstract in english Vesicovaginal fistula is an abnormal communication between the bladder and vagina and represents the most frequent type of fistula in the urinary tract. The most common cause in Brazil is iatrogenic fistula, secondary to histerectomia. Classically these women present continuous urinary leakage from [...] the vagina and absence of micturition, with strong negative impact on their quality of life. We present a case of totally continent vesicovaginal fistula, with a follow-up of 11 years with no complications.

Luís Gustavo Morato de, Toledo; Victor Espinheira, Santos; Paulo Eduardo Gourlat, Maron; Bruno César, Vedovato; Moacyr, Fucs; Marjo Deninson Cardenuto, Perez.

311

An assessment of interfractional uterine and cervical motion: Implications for radiotherapy target volume definition in gynaecological cancer  

International Nuclear Information System (INIS)

illing has more impact on uterine body position, highlighting the need for specific instructions on bladder and rectal filling for treatment. We propose an asymmetrical margin with CTV-PTV expansion of the uterus, cervix and upper vagina of 15 mm AP, 15 mm SI and 7 mm laterally and expansion of the nodal regions and parametria by 7 mm in all directions

312

Draft Genome Sequence of Lactobacillus plantarum CMPG5300, a Human Vaginal Isolate.  

Science.gov (United States)

The draft genome of a highly auto-aggregating Lactobacillus plantarum strain isolated from a human vagina is reported. The peculiar phenotype also provides an adhesive and co-aggregative potential with various pathogens, which could be of significance in the vaginal niche. Detailed genome analysis could aid in identifying the adhesins of the strain. PMID:25395634

Malik, Shweta; Siezen, Roland J; Renckens, Bernadet; Vaneechoutte, Mario; Vanderleyden, Jos; Lebeer, Sarah

2014-01-01

313

Laparoscopic Supracervical Hysterectomy  

Medline Plus

Full Text Available ... a later time? Yes. If you developed precancerous changes of the cervix or the cervix started to prolapse or relax out through the opening of the vagina, there is definitely a possibility that you might need to go back in at some point and remove that cervix. 00:22:03 CRANSTON ...

314

C-Section  

Medline Plus

Full Text Available ... the umbilical cord. The mother’s blood does NOT go into the baby’s body. When it is almost ... is not enough room for the baby to go through the vagina 4. The cervix does not ...

315

HIV and AIDS  

Medline Plus

Full Text Available ... body through tiny cuts or sores on the skin or the lining of the vagina, penis, rectum or mouth. Another common way of getting HIV is by sharing a needle or syringe with someone who has HIV. Infection – Facts • Between ¼ and ? of untreated pregnant ...

316

Mycoflora of cervicovaginal fluids in dairy cows with or without reproductive disorders.  

Science.gov (United States)

Fungal infection of reproduction system of dairy cattle have not been received much more attention. The aim of this study was to determine the fungal infection of Holstein dairy cows with reproductive disorders or healthy. Fungal isolates of cervicovaginal fluids of 176 Holstein dairy cows were collected by using the double rod swabs for cervix and the sterilized cotton swabs for discharges of vagina. They were evaluated for fungal infections. The treatment group included 70 dairy cows with reproductive diseases, such as abortion, repeat breeder, endometritis, metritis, retention of fetal membrane, dystocia, cervicitis, and vaginitis. The control groups were included 42 healthy non-pregnant cows and 64 pregnant cows. Isolates of fungi were obtained from cervix and vagina of 27.1% and 28.6% of treatment group, 26.7% and 31.2% of pregnant cows, and 33.3% and 21.4% of healthy non-pregnant cows, respectively, indicating no significant differences. It is showed that the cervix and vagina of the treatment group have been infected by six different mycotic isolates. However, the cervix and vagina of pregnant and non-pregnant healthy cows in control group were infected with 5, 6 and 5, 4 different fungal agents, respectively. Penicillium and yeast were the most common isolated agents. Regarding to the result of this study, it is concluded that fungal infections can occur in cervicovaginal cavity of Holstein dairy cows with or without reproductive diseases. PMID:17577679

Garoussi, Massoud Talebkhan; Khosrave, Ali Reza; Havareshti, Parviz

2007-08-01

317

Vaginal Birth  

Medline Plus

Full Text Available ... og190103 Last reviewed: 05/06/2013 5 2. Regional anesthesia 3. Epidural Block 4. Spinal anesthesia may be ... baby’s blood. This may make the baby groggy. Regional anesthesia is delivered with a needle through the vagina ...

318

C-Section  

Medline Plus

Full Text Available ... blood enters the placenta and delivers oxygen and nutrients to the baby’s blood. The mother’s blood also ... the vagina. When this happens, we say the “water broke.” Labor can start when the water breaks. ...

319

Vaginal Birth  

Medline Plus

Full Text Available ... during pregnancy. The mother’s blood delivers oxygen and nutrients to the baby’s blood through the placenta. The ... vagina. When this happens, we say the mother’s “water broke.” Labor should start if the water breaks. ...

320

Effects of sexual maturation and gonadal steroids on the localization of IgG-, IgM- and IgA-positive cells in the chicken oviduct.  

Science.gov (United States)

The effects of sexual maturation and gonadal steroids on the localization of immunoglobulin-positive cells in chicken oviducts were studied. Oviductal tissues were collected from laying hens and chicks treated with stilboestrol (DES, an analogue of oestrogen) or progesterone. Paraffin wax sections of the tissues were immunostained for IgG, IgM and IgA, and the frequency of cells staining positive was examined using an image analysis system. Some of the cells in the mucosal epithelium and plasma cell-like cells in the stroma of the oviduct stained positive for IgG, IgM or IgA. In the mucosal epithelium of laying hens, there was a significantly greater number of IgG-positive (IgG+) cells in the shell gland than in the infundibulum, magnum and isthmus, more IgM+ cells in the magnum than in the infundibulum, and more IgA+ cells in the magnum than in the other segments of the oviduct with the exception of the vagina. The frequency of IgG+ and IgM+ cells in the mucosal epithelium of all oviductal segments and IgA+ cells in the magnum, isthmus and vagina was significantly higher in laying hens than in immature birds. In the subepithelial stroma of laying hens, there was a significantly greater population of IgG+ cells in the infundibulum and vagina than in the magnum and isthmus, more IgM+ cells in the infundibulum than in the magnum, and more IgA+ cells in the uterovaginal junction and vagina than in the magnum and isthmus. The frequency of IgG+, IgM+ and IgA+ cells in the subepithelium of infundibulum, uterovaginal junction and vagina was significantly greater in laying hens than in immature birds. The number of IgM+ cells in all oviductal segments and of IgA+ cells in the magnum of the mucosal epithelium of the chicks treated with DES increased significantly compared with those of control chicks. In addition, the number of IgG+ cells in the shell gland and vagina and of IgM+ cells in the vagina of the stroma of DES-treated birds were increased. Treatment of immature birds with progesterone had no effect on the localization of Ig+ cells in the oviduct except for a decrease in the number of IgM+ cells in the shell gland. These results suggest that the local immunity in the oviduct develops during sexual maturation, possibly under the control of oestrogen. PMID:9462296

Zheng, W M; Yoshimura, Y; Tamura, T

1997-11-01

 
 
 
 
321

Efecto del método de obtención de semen de ovino sobre la calidad espermática (Effect of the method of obtaining of ovine semen on the spermatic quality  

Directory of Open Access Journals (Sweden)

Full Text Available La colecta del semen del ganado ovino, ayuda a identificar problemas relacionados con el desempeño reproductivo de estos animales. Se han utilizado diferentes pruebas laboratoriales, para valorar la calidad seminal de los ovinos y poder realizar predicciones indirectas del potencial reproductivo de los machos reproductores; no obstante, su naturaleza subjetiva, no asegura el poder de fecundación de los machos. El objetivo de este trabajo fue valorar el efecto del método de obtención del semen de ovinos sobre la calidad espermática. Se empelaron 10 machos ovinos de la raza Suffolk de una Unidad de Producción Ovina, ubicada en el Estado de México, México. Para la recolección seminal se utilizó vagina artificial y directamente de la vagina, después de la monta natural. El semen fue valorado macro y microscópicamente. Los resultados promedios fueron, para vagina artificial: volumen 1.11 ml, pH 6.62, motilidad 64.5 %, concentración de espermatozoides/ml 206.4 x106, vivos 68.5 %, Muertos 31.87% y anormalidades 23.96%; directamente de la vagina: volumen 0.57 ml, pH 6.75, motilidad 60.4%, concentración de espermatozoides/ml 176.02 x 106, vivos 62.62 %, muertos 37.27% y anormalidades 11.12%. Los resultados indican que los resultados obtenidos con vagina artificial fueron los mejores. The collection of the semen of the livestock ovine, helps to identify problems related with the reproductive acting of these animals. They have been used different you prove laboratories, to value the seminal quality of the ovines and power to carry out indirect predictions of the reproductive potential of the reproductive males; nevertheless, its subjective nature, doesn't assure the power of fecundation of the males. The objective of this work was to value the effect of the method of obtaining of the ovines semen on the spermatic quality. You empelaron 10 male ovines of the race Suffolk of a Unit of Production Ovine, located in the State of Mexico, Mexico. For the seminal gathering artificial vagina was used and directly of the vagina, after it mounts it natural. The semen was valued macro and microscopically. The results averages were, for artificial vagina: volume 1.11 ml, pH 6.62, motility 64.5%, concentration of sperms/ml 206.4 x106, alive 68.5%, Dead 31.87% and abnormalities 23.96%; directly of the vagina: volume 0.57 ml, pH 6.75, motility 60.4%, sperms/ml concentration 176.02 x 106, alive 62.62%, dead 37.27% and abnormalities 11.12%. The results indicate that the results obtained with artificial vagina were the best.

Córdova-Izquierdo, Alejandro1*; ; ; y

2006-08-01

322

The effect of semen collection method and level of egg yolk on capability of dilution and storage of buck semen  

Directory of Open Access Journals (Sweden)

Full Text Available The study was conducted to evaluate the effect of semen collection method for reduction of the deleterious interaction between the enzymes of bulbourethral gland and egg yolk during the dilution and storage of buck semen by three different level of egg yolk. Ten bucks were used in this study; the bucks were divided into two groups (five bucks in each group. Semen samples were collected once a week for four weeks from the bucks in first group using an artificial vagina, and from the animals in second group using an electroejaculator. The collected semen samples were diluted with sodium citrate extender with three different level of egg yolk (5, 10 and 20%. Extend semen samples were stored at 5 °C for three days. Computer assisted sperm analysis and Sperm Class Analyzer® were used for evaluation of the buck semen samples. Sperm motility parameters were evaluated which includes; percentage of motile sperm, percentage of progressive motile sperm, the value of the linear velocity (VSL, the value of the average velocity (VAP, the value of the curvilinear velocity (VCL, and the amplitude of lateral movement of the head (ALH. Results showed that all sperm motility parameters under the different level of egg yolk in semen samples that collected by artificial vagina were significantly higher than those which collected by electroejaculator. The percentage of motile sperm and progressive motile sperm of samples that collected by artificial vagina were higher at 10% of egg yolk, while these motility parameters were higher at 5% of egg yolk for semen samples that collected by electroejaculator. The differences between the two methods of semen collection in VCL and ALH were clear and the values were higher in samples that collected using the artificial vagina. The values of VSL, VAP and VCL of semen samples that collected by artificial vagina were higher at the second day than first day of semen storage under 10% of egg yolk. In conclusion, there are effects of the semen collection method on ability of dilution and storage of buck semen, and using of artificial vagina and 10% of egg yolk is recommended for buck semen dilution and storage.

N.N. Dhaher

2013-12-01

323

Morphological and functional characterization of a rat vaginal smooth muscle sphincter.  

Science.gov (United States)

The aim of the present study was to gain information about adrenergic-, cholinergic- and non-adrenergic, non-cholinergic (NANC)- transmitter systems/mediators in the rat vagina, and to characterize its smooth muscles functionally. Tissue sections from vagina of Sprague Dawley rats were immunolabelled with antibodies against protein gene product 9.5 (PGP), synaptophysin (Syn), tyrosine hydroxylase (TH), vesicular acetylcholine transporter (VAChT), neuropeptide Y (NPY), nitric oxide synthase (NOS), vasoactive intestinal polypeptide (VIP), calcitonin gene-related peptide (CGRP) and pituitary adenylate cyclase-activating polypeptide (PACAP). Circularly cut vaginal smooth muscle preparations from the distal vagina were studied in organ baths. In the paravaginal tissue, a large number of PGP-, NOS-, TH-, VIP-immunoreactive (IR) and few CGRP-IR nerve trunks were observed, giving off branches to the smooth muscle wall. The smooth muscle wall was supplied by a large number of PGP-, Syn-, VAChT-, NPY-, NOS- and TH- IR nerve terminals, whilst only a moderate to few numbers of CGRP-, VIP- and PACAP-IR terminals were identified. Especially the distal part of the vaginal wall, where the circularly running smooth muscle was thickened into a distinct sphincter structure, was very richly innervated, predominantly by PGP- and NOS-IR terminals. Below and within the basal parts of the epithelium in the distal half of the vagina, a large number of PGP- and few NOS- and PACAP-IR varicose terminals were observed. The vaginal arteries were encircled by plexuses of nerve terminals. A large number of these were PGP-, Syn-, VAChT-, NOS-, TH-, NPY- and VIP-IR, and few were CGRP- and PACAP-IR. In isolated preparations of the distal vagina, electrical field stimulation (EFS) caused frequency-dependent contractions, which were reduced by sildenafil, tetrodotoxin (TTX) and phentolamine. In preparations contracted by norepinephrine (NA), EFS produced frequency-dependent relaxations. Pretreatment with the NOS-inhibitor N(G)-nitro-L-arginine, TTX, or the inhibitor of soluble guanylate cyclase, ODQ, abolished the EFS relaxations. In NE precontracted preparations, cumulative addition of sildenafil caused concentration-dependent relaxation. Carbachol contracted the strips concentration-dependently from baseline. It can be concluded that the distal part of the rat vagina forms a distinct smooth muscle sphincter, which is richly innervated by adrenergic, cholinergic and NANC nerves. The present studies suggest that in the rat the L-arginine/NO-system not only plays an important role in the regulation of vaginal smooth muscle tone, but also affects blood flow, and may have sensory functions. PMID:12152117

Giraldi, A; Alm, P; Werkström, V; Myllymäki, L; Wagner, G; Andersson, K E

2002-08-01

324

The release of isoconazole nitrate from different suppository bases: in-vivo release of drug labelled with 99mTc in rabbits.  

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The influence of the suppository bases on the in-vivo release of 99mTc-labelled isoconazole nitrate was investigated. The single-dose vaginal suppository formulations for local treatment of vaginitis were prepared by a fusion method using polyethylene glycols, Witepsol H15, Novata BD and Cremao. Prepared vaginal suppositories containing solid-labelled substance were applied to the vagina of rabbits and at 0, 2 and 24 h after administration, the amounts of radioactivity in the vagina were detected by the SPECT Gamma Camera and the release rates of the drug were calculated. The percent released was found to be in the following order; polyethylene glycol (PEG) 6000 > PEG 4000 > Witepsol > PEG 1500 > Novata BD > Cremao. The results obtained in both in-vitro and in-vivo studies indicated that the vaginal suppository of isoconazole nitrate prepared with polyethylene glycols could confidently be used in therapy. PMID:8583381

Asikoglu, M; Ertan, G; Ercan, M T; Duman, Y

1995-09-01

325

Deceptive vulvar papillomavirus infection. A possible explanation for certain cases of vulvodynia.  

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Use of the colposcope for vulvar and vaginal examination in four cases of long-standing vulvodynia led to the identification of lesions with an unusual appearance. In the vulvar vestibule, epithelial projections resembling cactus, camel humps or stony colonial pavement were observed. In the vagina, the lesions looked more like cerebral folds. Biopsies of these lesions showed histopathologic changes diagnostic of human papillomavirus infection, scored according to Reid's criteria. In one case, capsid antigen was detected with the peroxidase technique in the nuclei of the superficial cells. Past history and positive findings in the sexual partners of some of the patients suggested long-standing herpesvirus activity in the lower genital tract. In some cases of recalcitrant vulvodynia, colposcopic examination of the vulva and vagina may lead to a viral explanation for symptoms previously considered psychosomatic in origin. PMID:3023608

di Paola, G R; Rueda, N G

1986-10-01

326

Úlcera genital aguda en paciente adolescente  

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Full Text Available La úlcera vulvar aguda o úlcera de Lipschütz es una entidad poco frecuente y habitualmente subdiagnosticada. Es reconocida por la aparición súbita de lesiones ulcerosas y dolorosas en vulva, vagina y/o periné, sin antecedente de contacto sexual previo. La etiología es desconocida. El diagnóstico diferencial debe incluir causa infecciosa venérea o no, síntoma de cuadro autoinmune u otra enfermedad sistémica, o efecto secundario a la administración de fármacos. Las lesiones desaparecen espontáneamente, habitualmente sin secuelas y sin recurrencias a largo plazo.Acute genital ulcer or Lipschütz ulcer is a rare and underdiagnosed, entity that usually presents an acute and painful ulcer in the vulva, lower vagina and/or perineum of nonvenereal origin. The etiology is unknown but the differential diagnosis must include sexually and nonsexually transmitted infections, autoimmune conditions, local manifestations of systemic illness and drug reactions. The lesions heal spontaneously and most patients have no recurrence and no long-term sequelae.

Patricia Rubio C

2012-01-01

327

Interstitial irradiation with Ir-192 for carcinoma of the female genital tract  

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Two patients treated with interstitial iridium-192 irradiation are presented. A patient with stage IV A adenocarcinoma of the uterine cervix was treated with external irradiation in combination with local hyperthermia prior to the interstitial irradiation. Another patient with stage III B squamous cell carcinoma of the vagina had a hysterectomy followed by irradiation 22 years prior to the treatment. Wires of Iridium-192 were put into place in the region of the tumor to give 40 Gy to the periphery of the tumor. The patient with carcinoma of the cervix died 15 months after the treatment. The patient with carcinoma of the vagina is well and has locally controlled disease 18 months after the treatment. (author)

328

Radiation tolerance of the vaginal mucosa  

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Sixteen patients with cancer of the vagina that were controlled locally for a minimum of eighteen months after teletherpay (T) or brachytherapy (B) or both (T and B), were analyzed for radiation tolerance of the vaginal mucosa. The site of vaginal necrosis did not always coincide with the site of the tumor. The posterior wall appeared more vulnerable than the anterior or lateral walls. For the distal vaginal mucosa, necrosis requiring surgical intervention occurred following combined T and B, if summated rad exceeded9800. The upper vagina tolerated higher dosages. No patient surgery for upper vaginal necrosis even though summated (T and B) dosage up to 14,000 rad was applied. Placing radioactive needles on the surface of the vaginal cylinder with or without interstitial perincal needles should be avoided. Further accumulation of data is needed to define these vaginal mucosa tolerance limits more closely

329

Mayer Rokitansky Kuster Hauser (MRKH) syndrome with absent thumbs and big toes.  

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Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome is a rare developmental failure of Müllerian ducts. Principle clinical features of MRKH syndrome are primary amenorrhoea associated with congenital absence of vagina, uterine anomalies, normal ovaries, 46 XX karyotype with normal female secondary sexual characteristics and frequent association with renal, skeletal, and other congenital anomalies. A case of a 3-year-old child with congenitally absent thumbs and big toes is reported herein; she was brought in with complaints of urinary incontinence. Radiological investigation (ultrasound and magnetic resonance imaging (MRI) scan) revealed absent uterus and vagina while both ovaries were normal. Intravenous urography (IVU) study showed bifid pelvicalyceal systems bilaterally. Karyotyping revealed a 46 XX female phenotype. Laparoscopy confirmed normal ovaries bilaterally and small unfused uterine buds lying beside both ovaries on each side of pelvis. Early diagnosis of MRKH syndrome is essential for timely planning of vaginal and (if possible) uterine reconstructive surgeries. PMID:24605721

Yunus, Mahira

2014-01-01

330

Mayer-Rokitansky-Kuster-Hauser Syndrome: Surgical Management of Two Cases  

Science.gov (United States)

The Mayer-Rokitansky-Kuster-Hauser (MRKH) Syndrome is a rare anomaly characterized by congenital aplasia of the uterus and vagina in women showing normal development of secondary sexual characters and normal 44 XX karyotype. We report our experience in the management of two patients with congenital absence of the vagina due to the MRKH syndrome. The first case was a 24-year-old student, who presented with primary amenorrhea, uterovaginal agenesis, right pelvi-ureteric junction obstruction, and left renal agenesis. The second patient was a 24-year-old housewife, who presented with primary amenorrhea and inability to achieve penetrative sexual intercourse. She had vaginal atresia and a grossly hypoplastic uterus. Both had successful sigmoid colovaginoplasty and are sexually active. Vaginal reconstruction using the sigmoid colon saw an immediate and satisfactory outcome in both patients PMID:22091331

Mungadi, I. A.; Ahmad, Y.; Yunusa, G. H.; Agwu, N. P.; Ismail, S.

2010-01-01

331

The effect of Lacto- and Bifidobacteria in monoculture on the vaginal microflora in norm and in cases of intravaginal staphylococcosis.  

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The influence of probiotic strains of Lactobacillus casei IMV B-7280, Lactobacillus acidophilus IMV B-7279, Bifidobacterium animalis VKL, Lactobacillus delbrueckii subsp. bulgaricus IMV B-7281 and Bifidobacterium animalis VKB, each strain separately, to the range of the urogenital tract microflora in physiological norm and in cases of experimental intravaginal staphylococcosis of mice induced by Staphylococcus aureus 8325-4. It was found that all these strains had different efficiency in Staphylococcus aureus 8325-4 growth suppression in the vagina of infected mice and affect the spectrum of microorganisms. Lactobacillus casei IMV B-7280 strain had effective antistaphylococcal effect and reduced the number of coliform bacteria and fungi in the vagina in cases of intravaginal staphylococcosis of mice. Lactobacillus casei IMV B-7280 strain is promising to create probiotic drugs effective in treating intravaginal staphylococcosis. PMID:23866586

Babenko, L R; Lazarenko, L M; Shynkarenko, L M; Mokrozub, V V; Pidgorskyi, V S; Spivak, M Ja

2013-01-01

332

FORMULATION, EVALUATION AND MICROBIAL ASSAY OF TINIDAZOLE VAGINAL SUPPOSITORY CONTAINING LACTIC ACID BACILLUS SPORES  

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Full Text Available Human vagina represents a dynamic ecosystem dominated by certain species of Lactobacillus. This microorganism restricts the growth of pathogens by using properties of steric exclusion and inhibitory substance production. Serious complications including bacterial vaginosis and vaginal cancer are often determined in women with reduced numbers of lactobacilli. Local application of Lactobacillus is consequently promising to keep the vagina colonized by this strain, which consequently reduces the infections. The first objective of this research was to develop a local application pharmaceutical formulation of a vaginal suppository containing lyophilized culture of Lactobacillus with anti-microbial agent tinidazole. The second objective was to establish its in vivo performance by developing in vitro methods of evaluation as well as antimicrobial activity of tinidazole alone with Lactic acid Bacillus Spores in vaginosis.

SC Shivhare*, AR Umarkar and PA Salunke

2014-07-01

333

Concomitant imperforate hymen and transverse vaginal septum complicated with pyocolpos and abdominovaginal fistula.  

Science.gov (United States)

A 13-year-old patient with a complaint of worsening lower abdominal pain during the past 4 months was admitted to the emergency department. An abdominopelvic ultrasound scan revealed a distended uterocervical cavity suggestive of hematometrocolpos. Imperforate hymen was observed on examination of the external genitalia. MRI scan revealed an air-fluid level representing pyometrocolpos within a distended vagina. Posterior vaginal extraperitoneal leakage as the sign of a fistula between the vagina and the rectovaginal space was detected. Although laparoscopic approach was planned, malodorous pus expelled after the insertion of the Veress needle, it was decided to proceed to laparotomy. Pus with peritoneal microabscess formations was observed at laparotomy. The imperforate hymen and TVS were excised vaginally. A more complex anomaly should be suspected in cases with hematometra and concomitant imperforated hymen without any bulging and thorough evaluation using radiological imaging techniques should be performed before surgical approach. PMID:24660080

Dilbaz, Berna; Kiykac Altinbas, Sadiman; Altinbas, Namik Kemal; Sengul, Ozlem; Dilbaz, Serdar

2014-01-01

334

The repair of rectovaginal fistulas using a bulbocavernosus muscle-fat flap.  

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A 50-year-old woman developed a rectovaginal fistula after a posterior colporrhaphy for rectocele repair. Her vagina was scarred and narrowed after radiotherapy for cervical cancer 20 years earlier. A second patient with a 23-year history of Crohn's disease presented with a small low rectovaginal fistula. The latter appeared spontaneously. Both complained of passing faeces and flatus through the vagina. Clinical examination confirmed the symptoms and revealed no signs of sphincter disturbance. As both patients had no other medical problems, we operated on the fistulas by a vaginal approach using a bulbocavernosus muscle-fat flap from the right labia majora. A temporary ileo- or colostomy could be avoided. Following successful healing, the anatomical and functional results were excellent in both cases. PMID:18979114

Reisenauer, Christl; Huebner, Markus; Wallwiener, Diethelm

2009-06-01

335

Surgical repair of rectovaginal fistula using gracilis muscular flap. A case report  

International Nuclear Information System (INIS)

A 78 year-old female suffered from vaginal discharge of flatus and stool for 20 years after the radiation therapy for cervical cancer. Digital and endoscopic examination of the rectum and the vagina disclosed a large, short rectovaginal fistula at the level of the cervix. Since laparotomy and low anterior resection of the rectum were impossible, a perineal approach was adopted. After perineal skin incision, the fistula was resected and the defects of the rectum and the vagina were closed. Gracilis muscular flap was anchored between the two closures. Though the closure of the rectal side was torn, her postoperative course was uneventful. Endoscopic examination 24 days after the operation confirmed healing of the dehiscence. The results verified the usefulness of the perineal approach using the gracilis muscular flap as an alternative method to low anterior resection for troublesome radiation induced rectovaginal fistula. (author)

336

 

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Full Text Available A study of 404 women that attended the Microbiology Laboratory of "Ramón Gonzalez Coro" Gynecoobstetric Hospital, in Havana City, was conducted aimed at identifying species of yeasts isolated from Pap smears, registering the signs and clinical symptoms and determining the risk factors associated with infection. The isolated yeasts were identified by the filamentation tests in serum, production of chlamydoconidia and carbohydrate assimilation. It was found that 138 (34.16 % of women had yeasts in the vagina. 3 genera were identified: Candida (88.49 %. Trichosporon (10.79 % and Rhodotorula (0.72 %. Pruritus and heat showed statistical significance (p<0.01. Pregnancy, the use of IUD and the antibacterial therapy proved to be the most common risk factors in relation to the presence of Candida in the vagina.

2004-04-01

337

Mayer-Rokitansky-Kuster-Hauser syndrome with hyperprolactinemia.  

Science.gov (United States)

Mayer-Rokitansky-Kuster-Hauser Syndrome in association with hyperprolactinemia is very rare. An 18-year-old, Saudi, single, virgin female was accompanied by her mother seeking medical advice regarding absent menses. She had normal breasts, normal axillary and pubic hair, normal vulva, urethra, and labial folds, however, the vagina was blind, approximately 2 cm length. Pelvic magnetic resonance imaging showed normal appearing ovaries, a small uterus and small cervix and vagina. Investigations showed initial high serum prolactin of 1,517 mIU/L. Cranial MRI was normal. The patient was diagnosed as mullerian hypoplasia class I American Fertility Society. After an extensive literature search, we present a unique case of concomitant occurrence of MRKH, in the form of mullerian hypoplasia, and hyperprolactinemia. PMID:18521475

Al-Jaroudi, Dania H; Nasser, Ayda M

2008-06-01

338

AIDS-related Kaposi sarcoma: findings on thallium-201 scintigraphy  

International Nuclear Information System (INIS)

No simple, noninvasive method is available for evaluating extracutaneous Kaposi sarcoma in AIDS patients or for following the tumor's response to treatment. We report our preliminary experience with thallium-201 scintigraphy in nine AIDS patients with proved Kaposi sarcoma. Eight of the nine had abnormal uptake of the radionuclide in skin, lymph nodes, oral cavity, vagina, and lungs. Only four of the nine had cutaneous Kaposi sarcoma at the time of scanning. All cutaneous and mucosal lesions were thallium avid. Two of the six patients with thallium-avid nodes underwent nodal biopsy. Both biopsies confirmed the diagnosis of Kaposi sarcoma. Cutaneous Kaposi sarcoma developed later in one of these patients, showing the efficacy of thallium scintigraphy for the early detection of extracutaneous lesions. These preliminary results show thallium avidity in Kaposi sarcoma involving the skin and various extracutaneous sites (lymph nodes, lung, mucosa, and vagina). Thallium scintigraphy is a potentially useful procedure for detecting extracutaneous Kaposi sarcoma in AIDS patients

339

Analysis of complications for the treatment of uterine fibroids with bilateral uterine artery superselective embolization  

International Nuclear Information System (INIS)

Objective: To discuss the complications of the bilateral uterine artery superselective embolization for uterine fibroids. Methods: Forty one cases (mean 42 years old) with uterine fibroids were approached by right femoral artery puncture; including thirty six cases of single hysteromyoma (33 cases with diameter 10 cm). and 5 cases of multi hysteromyoma. Bilateral uterine artery super selective 5F catheterization embolization were done along uterine descending artery (neck of uterus to vagina) with PVA particles. Results: Embolization succeeded with 100% and effective ratio was 90.3%. Sixteen of these cases showed post embolization syndrome, with something outflowed from vagina and 10 cases showed changes of emmenia but with no serious complications in all 41 cases. Conclusion: Using bilateral uterine artery superselective embolization for uterine fibroids with PVA grains can decrease the incidence of complications. (authors)

340

Sawadalepis prima n. g., n. sp. (Cestoda: Cyclophyllidea) from the Schreiber's bent-winged bat Miniopterus schreibersii Kuhl (Chiroptera: Vespertilionidae) from China.  

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Sawadalepis n. g. is erected for Sawadalepis prima n. sp. in Schreiber's bent-winged bat Miniopterus schreibersii Kuhl (Chiroptera: Vespertilionidae) from southern China. Diagnostic features of the currently monotypic genus include attributes of the osmoregulatory system and female genital organs. The dorsal osmoregulatory canals are shifted bilaterally towards the margins of proglottides in relation to the ventral canals. The genital pores are unilateral and sinistral. Among female attributes, the copulatory part of the vagina is covered externally by a dense layer of intensely stained cells; the conductive part of the vagina is clearly distinguishable from the seminal receptacle; the uterus has ventral and dorsal diverticula, extending bilaterally beyond the longitudinal osmoregulatory canals; and the eggs are spherical with thick outer coat. PMID:23949650

Makarikova, Tatiana A; Makarikov, Arseny A

2013-09-01

 
 
 
 
341

Modified supralevator pelvic exenteration for the treatment of locally advanced rectal cancer with vaginal and uterine invasion.  

Science.gov (United States)

Post-chemoradiation T4 rectal cancer remains a therapeutic challenge and an aggressive surgical approach is the only chance for a cure. Rectal lesions infiltrating the upper vaginal wall and uterine cervix are usually treated by low anterior resection with en bloc removal of the vagina and uterus. However, failure can occur when one is trying to access the anterior recto-vaginal plane below the tumor, especially in obese patients with a narrow pelvis. The remaining surgical alternatives are aggressive and debilitating. The objective of the study is to describe a modified supralevator pelvic exenteration for selected patients. A new surgical option is added to the armamentarium of the oncologic surgeon. The discussion focuses on the indications for this surgical technique and its advantages, such as the preservation of the anal sphincter and the vagina, thus allowing for fecal continence and sexual activity. PMID:22907785

Dias, André Roncon; Nahas, Sérgio Carlos

2013-06-01

342

Natural orifice transluminal endoscopic surgery: The transvaginal route moving forward from cholecystectomy  

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Full Text Available The advent of minimally invasive surgery and the advances in endoluminal flexible endoscopy have converged to generate a new concept in digestive surgery, whose acronym natural orifice transluminal endoscopic surgery (NOTES, has become a familiar term in the surgical community. NOTES has been performed through the mouth, the bladder, the rectum and the vagina. Of these four approaches, the vagina has gained most popularity for several reasons. It is not only readily accessible and easy to decontaminate but it also provides safe entry and simple closure. The transvaginal approach has been described in the experimental and the clinical setting as an option for cholecystectomy, nephrectomy, splenectomy, segmental gastrectomy, retroperitoneal exploration and bariatric surgery. However, larger series are needed to delineate the exact risks of this approach, and to transcend cultural barriers that impede its wider introduction. Prospective randomized trials will shed light on the definitive role of the vaginal approach in minimal invasive surgery of the future.

Eduardo M Targarona

2010-06-01

343

Concomitant Imperforate Hymen and Transverse Vaginal Septum Complicated with Pyocolpos and Abdominovaginal Fistula  

Science.gov (United States)

A 13-year-old patient with a complaint of worsening lower abdominal pain during the past 4 months was admitted to the emergency department. An abdominopelvic ultrasound scan revealed a distended uterocervical cavity suggestive of hematometrocolpos. Imperforate hymen was observed on examination of the external genitalia. MRI scan revealed an air-fluid level representing pyometrocolpos within a distended vagina. Posterior vaginal extraperitoneal leakage as the sign of a fistula between the vagina and the rectovaginal space was detected. Although laparoscopic approach was planned, malodorous pus expelled after the insertion of the Veress needle, it was decided to proceed to laparotomy. Pus with peritoneal microabscess formations was observed at laparotomy. The imperforate hymen and TVS were excised vaginally. A more complex anomaly should be suspected in cases with hematometra and concomitant imperforated hymen without any bulging and thorough evaluation using radiological imaging techniques should be performed before surgical approach. PMID:24660080

Dilbaz, Berna; Kiykac Altinbas, Sadiman; Altinbas, Namik Kemal; Sengul, Ozlem; Dilbaz, Serdar

2014-01-01

344

[Vesico-vaginal fistula with a giant vesico-vaginal stone: a case report].  

Science.gov (United States)

The patient, a 73-year-old woman, had undergone hysterectomy and irradiation therapy 26 years ago. On September 4, 1997, the patient was referred to our hospital, and presented with low grade fever and lower abdominal dull pain of a one-month duration. Radiologic and vaginal examinations revealed bilateral hydronephrosis and a giant stone lying down between the bladder and vagina. Vaginal incontinence showed the presence of the vesico-vaginal fistula. She underwent bilateral ureterocutaneostomy and cystolithotomy. A giant vesico-vaginal stone was removed by using a hammer and chisel. It weighed 180 g. The stone was composed of calcium phosphate and magnesium ammonium phosphate. Persistent infection of the bladder and the vagina may have been a possible etiological factor of the vesico-vaginal stone formation. Three weeks after the operation, bilateral hydronephrosis was improved. PMID:9752611

Segawa, N; Katsuoka, Y; Kaneda, K

1998-07-01

345

Transvaginal-laparoscopic anterior rectum resection in a hysterectomized woman with deep-infiltrating endometriosis: Description of a gynecologic natural orifice transendoluminal surgery approach  

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Deep-infiltrating endometriosis may affect the vagina, the rectum, and the cervicoisthmic part of the uterus, resulting in severe pain, particularly dyschezia, dysmenorrhea, dyspareunia, and diminished quality of life. Advanced surgical techniques, such as laparoscopic-assisted anterior rectum resection, are recognized as safe and effective therapeutic approaches. In some cases, a laparotomy or minilaparotomy has to be performed for technical reasons. This can be avoided in some cases by tran...

Ebert, A. D.; Burkhardt, T.; Parlayan, S.; Riediger, H.; Papadopoulos, T.

2009-01-01

346

Our experience of the use of Martius method to eliminate the vesicovaginal fistula  

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Sometimes after delivery, gynecological or other surgeries, radiological therapy, or destructions of vesico-vaginal septum due to the tumor or trauma, the unnatural communication between the bladder and vagina occurs. Those are fistulas that occur after the delivery (tocogenic) caused by the prolonged delivery or some obstetrics operations 1,2. Some fistulas are high, coming from the fundus of the bladder, medium, if they come just behind the trigonum of the bladder, and low, if they are in t...

Stanojevi? Dušan; Perovi? S.; ?or?evi? M.

2004-01-01

347

Genital Prolaps Fixation in Buffalo  

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Prolapse of the vagina and cervix is a disorder of ruminants normally in late gestation. Different methods used for prolapsed vagia treatment that Winkler’s cervix fixation is one of them.In this procedure to prevent displacement of the cervix caudally, anchoring it by using nonabsorbable sutures or nylon tape to the prepubic tendon or the sacrosciatic ligaments. Although the technique as being done under caudal epidural anesthesia. A cutting U form needle (10 cm) applicated for sutures of ...

Rahim Beheshti; Kambiz Valiei; Muhammad-Reza Valilu; Jamshid Giasi Ghalekandi

2011-01-01

348

Female circumcision: a risk factor in postpartum haemorrhage.  

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Full Text Available A major postpartum haemorrhage occurred in a patient with a previous history of female circumcision. Following assisted vaginal delivery 6 litre blood loss occurred as a result of tears to the vagina and perineum. The tears were sutured, followed by insertion of vaginal packs. Replacement fluid therapy was given. To reduce the incidence of tears and accompanying haemorrhage, it is advisable to perform two episiotomies viz. anterior and midline posterior or mediolateral.

McSwiney M

1992-07-01

349

Pornô Porn  

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Este artigo analisa os enunciados sobre corpos e sexualidade presentes em uma ampla linha de produções pornô com mulheres obesas. Nessa filmografia, o foco não recai em genitais e nádegas (os quais geralmente nem chegam a ser expostos), mas nos estômagos das atrizes. A representação pornográfica consiste no ato de mostrar mulheres gordas comendo alimentos ricos em gordura. A penetração do pênis ou de outro objeto na vagina, típica do pornô mainstream, é substituída pela imagem...

Don Kulick

2012-01-01

350

Diagnostic and therapeutic problems in a case of prenatally detected fetal hydrocolpos.  

Science.gov (United States)

We report on a female fetus with prenatally suspected hydrometrocolpos. Postnatal evaluation additionally revealed ambiguous genitalia, anorectal atresia, vertebral segmentation anomalies and congenital intestinal aganglionosis. Colostomy was performed, but postoperative recovery was complicated by pulmonary hypertension and renal failure, resulting in death at day 18. Postmortem examination furthermore revealed a small ventricular septal defect, as well as rectovaginal and urethrovaginal fistulae, causing massive dilatation of the septated vagina (hydrocolpos). The possibility of an overlapping VACTERL and MURCS association is discussed. PMID:11530001

Geipel, A; Berg, C; Germer, U; Ahrens, P; Gloeckner-Hofmann, K; Möller, J; Gembruch, U

2001-08-01

351

Neonatal hydrometrocolpos -a case report-  

International Nuclear Information System (INIS)

Neonatal hydrometrocolpos is a rare congenital disorder consisting of cystic dilatation of the vagina and uterus resulting from imperforate hymen or vaginal stresia. We report 3 cases of vaginal atresia, case with hydrometrocolpos associated with polydactyly and 2 cases combined with persistent urogenital sinus and imperforate anus. In each case, a sonograph showed a characteristic cystic abdominal mass containing a fluid/debris shadow with an interphase

352

Apedunculata discoidea gen. n., sp. n. (Monogenea: Dactylogyridae) parasitic on Prochilodus lineatus (Valenciennes, 1837) (Characiformes: Prochilodontidae) from southeastern Brazil Apeduncullata discoidea gen. n., sp. n. (Monogenea: Dactylogyridae) parasito de Prochilodus lineatus (Valenciennes, 1837) (Characiformes: Prochilodontidae) do sudeste do Brasil  

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A new species of dactylogyrid monogenean, Apedunculata discoidea gen. n., sp. n. is described and illustrated from the gills of the freshwater fish Prochilodus lineatus (Valenciennes, 1837) in pisciculture ponds from Pirassununga, São Paulo, Brazil. Diagnostic characters of the new genus and species are: 1) vagina dextrolateral slightly sclerotised, opening anteriorly at level of copulatory complex; 2) copulatory organ coiled with two counterclockwise rings; 3) Accessory piece distal and not...

Am, Cuglianna; Ns, Cordeiro; Jl, Luque

2009-01-01

353

A NEW SPECIES PHOREIOBOTHRIUM GAWALI FROM CARCHARIAS ACUTUS (MULLER AND HENLE, 1906 AT BANKOT, RATNAGIRI M.S. INDIA  

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Full Text Available A new species of Cestode Phoreiobothrium gawali was erected form the marine fish Carcharias acutus (Muller and Henle, 1841 collected from Bankot, Ratnagiri (West coast of India. We have described this new species in the genus Phoreiobothrium (LINTON 1989 We found P. gawali different from other species in body measurement, scolex length, breadth, sucker, neck, testes, ovary, vagina, genital pore, vitellaria, host and locality.

Pawar LB*, Shewale SS, Patil DN and RR Dandwate

2013-08-01

354

UTILIZAÇÃO DE GLICEROL E ETILENOGLICOL COMO CRIOPROTETORES NA CONGELAÇÃO DO SÊMEN CAPRINO  

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Dez amostras de sêmen de dois reprodutores caprinos, da raça Parda-alpina, colhidas em vagina artificial, foram submetidas a quatro tratamentos para avaliação da eficiência do etilenoglicol e do glicerol, associados ou não ao EDTA, na criopreservação da célula espermática caprina. O diluente usado era à base de Tris-gema de ovo contendo 7% de glicerol (glicerol E glicerol+EDTA) ou 7% de etilenoglicol (etilenoglicol e etilenoglicol + EDTA), sendo que nos grupos glicerol+EDTA e etile...

Ana Paula Portela; Marcos Chalhoub; Rafael Bruno Santos Teixeira; Rogério Furst; Anselmo Domingos Ferreira Santos; Antônio de Lisboa Ribeiro; Rodrigo Freitas Bittencourt; Sidney Gonçalves Gonzalez Alves; Ana Karine Almeida; José Domingos Guimarães

2006-01-01

355

Complex Genital Malformation in a Female with Congenital Adrenal Hyperplasia: Evaluation with Magnetic Resonance Imaging  

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This is a case of complex genital malformation in a young patient with congenital adrenal hyperplasia. The magnetic resonance imaging (MRI) findings included ostium of the vagina into the urethra (common urogenital opening), prostate-like tissue surrounding the urethra, and hyperplasia of the left adrenal gland. The report provides information on the clinical findings, the MRI examination, including the applied sequences and the MR findings, and gives an overview of the disease pattern and its frequency of occurrence.

Klessen, C.; Asbach, P.; Hein, P. A.; Beyersdorff, D.; Hamm, B.; Taupitz, M. [Humboldt-Univ. of Berlin, Campus Charite Mitte (Germany). Dept. of Radiology

2005-12-01

356

Characterization of the Uterus and Mammary Glands of the Female African Giant Rats (Cricetomys gambianus, Waterhouse) in Nigeria Caracterización del Útero y Glándulas Mamarias de la Rata Africana Gigante Hembra (Cricetomys gambianus, Waterhouse) en Nigeria  

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Morphology of the uterus and mammary glands were studied in sexually matured female African giant rat. The uterus was identified as being duplex, having two separate uterine horns and two cervices. The two cervices were partially fused and separated by a mid-saggital septum. Their thick musculatures projected caudally into the vagina as the portio vaginalis uteri. The results also showed that eight mammary glands, distributed along the lateral aspects of thoracic and inguinal regions, were pr...

Adebayo Koyuum Akinloye; Bankole Olusiji Oke

2010-01-01

357

Apedunculata discoidea gen. n., sp. n. (Monogenea: Dactylogyridae) parasitic on Prochilodus lineatus (Valenciennes, 1837) (Characiformes: Prochilodontidae) from southeastern Brazil.  

Science.gov (United States)

A new species of dactylogyrid monogenean, Apedunculata discoidea gen. n., sp. n. is described and illustrated from the gills of the freshwater fish Prochilodus lineatus (Valenciennes, 1837) in pisciculture ponds from Pirassununga, São Paulo, Brazil. Diagnostic characters of the new genus and species are: 1) vagina dextrolateral slightly sclerotised, opening anteriorly at level of copulatory complex; 2) copulatory organ coiled with two counterclockwise rings; 3) Accessory piece distal and not articulated; 4) body disk-shaped, lacking a peduncle. PMID:19802450

Cuglianna, A M; Cordeiro, N S; Luque, J L

2009-08-01

358

FEASIBILITY OF DNA DIAGNOSIS OF HAEMOGLOBINOPATHIES ON COELOCENTESIS  

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Abstract At 5-12 weeks of gestation the amniotic sac is surrounded by celomic fluid which contains cells of fetal origin. This fluid can be sampled by celocentesis, which involves the ultrasound-guided insertion of a needle through the vagina. The aim of this study was to examine the feasibility of prenatal diagnosis of hemoglobinopathies from the celomic fluid using a specific protocol. Celocentesis was performed at 7-9 weeks’ gestation in 26 singleton pregnancies at risk for he...

2011-01-01

359

Limnomermis subtropicalis n. sp. (Nematoda:Mermithidae) a Parasite of Larvae of Simulium orbitale Lutz (Diptera:Simuliidae) in Argentina  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in english Limnomermis subtropicalis n. sp. (Nematoda: Mermithidae) a parasite of Simulium orbitale Lutz (Diptera: Simuliidae) found in Argentina is described and illustrated. This species is characterized by having medium sized amphids, pocket-shaped, medium sized vagina, sculptured spicule, and by having 9 [...] preanal, 7 postanal papillae in the ventral row, and 12 papillae in the lateral rows

L Cristina de, Villalobos; Nora B, Camino.

360

DISORDER OF SEX DEVELOPMENT: DESCRIPTION OF 2 CASES OF MALE PSEUDOHERMAPHRODITISM  

Directory of Open Access Journals (Sweden)

Full Text Available Introduction. "Genetic errors" with malformations and hormonal alterations result in a broad spectrum of disorders of sexual identity difficult to classify for etiopathogenesis and anatomy. Male pseudohermaphroditism (PEM is the result of defects in masculinisation, persistence of mullerian ducts or genital malformations. In these patients, there is always a 46 XY karyotype, male gonads with the external genitalia and phenotype completely or partially female. The authors describe 2 cases of PEM. Patients and Methods. RS and HNA, 9 and 15 years old. Both had 46 XY karyotype and female phenotype with the presence of penile clitoris and small vagina. The urethral meatus was positioned at the base of the penile clitoris and upper vagina and testicles, were located at the proximal portion of the inguinal canal.Patients were subjected to MRI showing absence of uterus and ovaries. The endoscopy described a small vagina dead-end about 4-5 cm long. Complete resection of the vagina, bilateral orchiopexy, correction of perineal hypospadias with urethral tubulization, reconstruction of the scrotum, with the results of penoscrotal hypospadias were performed. Discussion. Sexual differentiation is the process between VII and XII weeks of gestational age leading to formation of male or female fetus from embryo potentially bisexual. Brain Code gender is bipolar: male or female. In the sexual disorders there is a discrepancy between anatomical sex and the brain code. Genital malformation with a direct mechanism (external genitalia and indirect (prenatal pathological imprinting on all the receptors of target organs may exacerbate the brain deterioration of the code resulting in disease patterns difficult to manage according psychological and surgical aspects. Conclusions. Pediatric Surgeon plays a key role in the treatment of genital anomalies. Valutation of pelvic-perineal anatomy is important for the choice of sexual phenotype and related surgical strategy. Early correction of genital abnormality may effectively prevent the child present psychological, behavioral onsequences and problems in family and society.

M. Messina

2009-11-01

 
 
 
 
361

Malformations in a cohort of 284 women with Mayer-Rokitansky-K?ster-Hauser syndrome (MRKH)  

Science.gov (United States)

Background The aim of this retrospective study was to describe the spectrum of genital and associated malformations in women with Mayer-Rokitansky-Küster-Hauser syndrome using evaluated diagnostic procedures and the Vagina Cervix Uterus Adnex – associated Malformation classification system (VCUAM). Methods 290 women with MRKH syndrome were clinically evaluated with using clinical examinations, abdominal and perineal/rectal ultrasound, MRI, and laparoscopy. Results Classification of female genital malformation according to the Vagina Cervix Uterus Adnex – associated Malformation classification system was possible in 284 women (97.9%). Complete atresia of Vagina (V5b) and bilateral atresia of Cervix (C2b) were found in 284 patients (100%). Uterus: bilateral rudimentary or a plastic uterine horns were found in 239 women (84.2%). Adnexa: normal Adnexa were found in 248 women (87.3%). Malformations: associated malformations were found in 126 of 282 evaluable women (44.7%), 84 women (29.6%) had malformations of the renal system. Of 284 women with Mayer-Rokitansky-Küster-Hauser syndrome 212 women (74.7%) could be classified as V5bC2bU4bA0. The most frequent classification was V5bC2bU4bA0M0 (46.8%) diagnosed in 133 of 284 women. Conclusions Complete atresia of vagina and cervix were found in all patients, variable malformations were found with uterus and adnexa. A variety of associated malformations were present, predominantly of the renal system. It is therefore recommended that all patients with genital malformations should be evaluated for renal abnormalities. PMID:22906151

2012-01-01

362

[Mayer-Rokitansky-Küster-Hauser syndrome. A report of two cases].  

Science.gov (United States)

The Mayer-Rokitansky-Kuster-Hauser is a rare congenital anomaly characterized by lack of vaginal and uterine development variable and normal ovaries. It results from agenesis or hypoplasia Müller duct system. Cervicovaginal agenesis as part of the complex syndrome, is even rarer. We report two cases: adolescent patient with primary amenorrhea, cervicovaginal agenesis and chronic pelvic pain, and a 28-year-old patient with primary amenorrhea, congenital absence of uterus and vagina. PMID:23240231

Bautista-Gómez, Esperanza; Morales-García, Víctor; Galván Espinosa, Honorio; Flores-Romero, Ana Luisa; Vásquez Santiago, Edmundo; Pizarro Osorno, Noel

2012-10-01

363

Mayer-Rokitansky-Kuster-Hauser (MRKH Syndrome Type 2: Atypical Presentation of Rare Case  

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Full Text Available Mayer-Rokitansky-Kuster-Hauser (MRKH syndrome is a congenital malformation characterized by an absence of the vagina associated with a variable abnormality of the uterus and the urinary tract but functional ovaries. We are reporting atypical presentation of rare case. Patient had obstructed left inguinal hernia with genitourinary and skeletal deformity. Latter it diagnosed as Mayer-Rokitansky-Kuster-Hauser (MRKH syndrome which is a rare disease. [Natl J Med Res 2013; 3(4.000: 409-411

Ashok Nakum

2013-08-01

364

Does Cancer Start in the Womb? Altered Mammary Gland Development and Predisposition to Breast Cancer due to in Utero Exposure to Endocrine Disruptors  

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We are now witnessing a resurgence of theories of development and carcinogenesis in which the environment is again being accepted as a major player in phenotype determination. Perturbations in the fetal environment predispose an individual to disease that only becomes apparent in adulthood. For example, gestational exposure to diethylstilbestrol resulted in clear cell carcinoma of the vagina and breast cancer. In this review the effects of the endocrine disruptor bisphenol-A (BPA) on mammary ...

Soto, Ana M.; Brisken, Cathrin; Schaeberle, Cheryl; Sonnenschein, Carlos

2013-01-01

365

Adenocarcinoma de Células Claras de Endocérvice em Menina de 7 anos Clear Cell Adenocarcinoma of the Endocervix in a 7-year-old Child  

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O adenocarcinoma de células claras de colo e vagina em adolescentes é uma doença rara e na maioria das vezes associada com o uso do dietilestilbestrol (DES) durante a gestação. A queixa mais freqüente é o sangramento vaginal irregular que pode ser incorretamente interpretado como vaginite nas crianças e como alterações do eixo hipotálamo-hipófise nas adolescentes. Relatamos o caso de adenocarcinoma de células claras de endocérvice em uma menina de 7 anos de idade atendida no Amb...

Marta Francis Benevides Rehme; Mauro Fernando Kürten Ihlenfeld; Ana Carolina Silva Chuery

1998-01-01

366

Macroscopic Morphometric Analysis of Genital Organs of Rabbit does with Differing Parturitions at 24 Hours Post-weaning / Análisis Morfométrico Macroscópico de Órganos Genitales de Conejas con Diferentes Partos a las 24 Horas Post-destete  

Scientific Electronic Library Online (English)

Full Text Available SciELO Chile | Language: English Abstract in spanish El propósito de este estudio fue analizar la morfometría macroscópica de los ovarios, útero y vagina en conejas de primero, segundo y tercer parto a las 24 horas post-destete con el propósito de determinar si existen diferencias entre los partos. El destete de la camada se realizó a los 30 días desp [...] ués del parto y 24 horas después fueron eutanasiadas. De cada animal se removieron los ovarios derecho e izquierdo, cuernos-cuello uterinos derecho e izquierdo y la vagina y se midió la longitud de cada uno de los órganos genitales. Se encontraron diferencias significativas en la longitud del ovario derecho entre el grupo de primer parto con respecto al de segundo y tercer parto (P 0,05 y P 0,01). Además, la longitud media de ovario izquierdo fue significativamente diferente entre el grupo de primero y segundo parto con respecto al de tercer parto (P Abstract in english The purpose of this study was to analyze the macroscopic morphometry of the ovaries, uterus and vagina in rabbit does in the first, second and third parturition at 24 hours post-weaning in order to determine if there are differences between parturitions. Weaning of the litter was performed at 30 day [...] s post-partum and 24 hours later the does were euthanized. Right and left ovaries, uterine horns-cervix and vagina were removed, and the length of each one was measured. Significant differences were found in the average of the right ovary length between the first group with respect to second and third parturition group (P 0.05 and P 0.01). Also, left ovary length was different between the first and second with respect to third parturition group (P

Jesús, Aragón-Hernández; Fernando Iván, Flores-Pérez; Claudia, Hallal-Calleros; Mario, Pérez-Martínez.

2013-09-01

367

Insects are Crawling in My Genital Warts  

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A 23-year-old woman presented with large exophytic genital wart arising from perineum, vulva, introitus of the vagina, and inner aspect of thighs. Patient developed severe itching and formication (insect-crawling sensation) in the lesions for past 1 week, though careful examination did not reveal any insects. Considering that the disease was causing psychological stress and physical symptoms, radiofrequency excision was planned. However, during the procedure, several maggots appeared from the...

Dhawan, Jyoti; Singh, Saurabh; Gupta, Somesh

2011-01-01

368

[Atrispinum mormyri (Lorenz, 1878) n. comb. (Microcotylidae: Atriasterinae) parasites of Lithognathus mormyrus (L.)].  

Science.gov (United States)

Atrispinum mormyri (Lorenz, 1878) n. comb. is proposed for Microcotyle mormyri collected on the gills of Lithognathus mormyrus (L.), from the Adriatic and Tyrrhenean Seas on the base of the structure of the genital atrium and the presence of a single vagina with dorsal aperture. The species is included in the keys given by Maillard e Noisy (1978-79) for the species grouped into the genus Atrispinum. PMID:6543941

Orecchia, P; Paggi, L

1983-04-01

369

Síndrome de Mayer-Rokitansky-Kuster-Hauser: a propósito de un caso  

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Se presenta caso de una paciente de 26 años de edad, que acude a consulta por amenorrea primaria. Examen físico: fenotípicamente femenina, cuello de base ancha, genitales externos normales, genitales internos con ausencia de vagina. Exámenes complementarios: ecografía abdomino-pélvica, TAC de abdomen y pelvis, urografía de eliminación: ausencia de útero, riñón izquierdo y su sistema excretor; riñón derecho único, rotado y ectópico (pélvico), con ectasia del sistema excretor. R...

Belkis Colmenares; Jesús Colmenares; Ottoniel Vilela; José Francisco Alonso

2007-01-01

370

[First record of Microsomacanthus tuvensis Spasskaya et Spasskii, 1961 (Cestoda, Hymenolepididae) in Poland].  

Science.gov (United States)

During standard parasitological studies of the tufted duck Aythya fuligula, obtained from fishermen from West Pomerania in December 2007, three cestode specimens were found in the jejunum of one male host. They were determinated as Microsomacanthus tuvensis (Spasskaya et Spasskii, 1961) on the basis of the cirrus's and cirrus sac's size and vagina's shape. This is the first record of this species in Poland. PMID:20209817

Królaczyk, Katarzyna; Kavetska, Katarzyna M; Kornyushin, Vadim V; Kalisi?ska, Elzbieta

2009-01-01

371

Neonatal hydrometrocolpos -a case report-  

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Neonatal hydrometrocolpos is a rare congenital disorder consisting of cystic dilatation of the vagina and uterus resulting from imperforate hymen or vaginal stresia. We report 3 cases of vaginal atresia, case with hydrometrocolpos associated with polydactyly and 2 cases combined with persistent urogenital sinus and imperforate anus. In each case, a sonograph showed a characteristic cystic abdominal mass containing a fluid/debris shadow with an interphase.

Kim, Hyang Sun; Kim, Ok Wha; Kim, Choon Yul; Bahk, Yong Whee [Catholic University Medical College, Seoul (Korea, Republic of)

1991-07-15

372

Pyocolpos in a 4 year old: a rare scenario  

Directory of Open Access Journals (Sweden)

Full Text Available Pyocolpos is cystic dilatation of vagina due to accumulation of pus resulting from genital tract obstruction. Hydrocolpos or pyocolpos are usually encountered either in the neonatal period due to stimulation from maternal hormones or at menarche. Their occurrence beyond infancy and before puberty is rare. We report this rare case of pyocolpos in a 4 year old child. [Int J Reprod Contracept Obstet Gynecol 2013; 2(3.000: 488-490

Neha Agarwal

2013-06-01

373

Hidrocolpos e hidrometrocolpos neoanatal: a propósito de un caso clínico / Neonatal hydrocolpos and hydrometrocolpos: a clinical case  

Scientific Electronic Library Online (English)

Full Text Available SciELO Chile | Language: Spanish Abstract in spanish El Hidrocolpos e Hidrometrocolpos es una condición caracterizada por dilatación quística de la vagina y/o del útero, con acumulación de líquido como resultado de obstrucciones vaginales congénitas. Puede ser de tipo secretorio o urinario, este último ocurre cuando existe comunicación vagino-vesical, [...] como en el seno urogenital o anomalía tipo cloaca. Otras causas son septo vaginal, himen imperforado, malformación tipo cloaca y senourogenital. Caso: Recién nacida de 10 días, 46 XX, con virilización de genitales grado IV de Prader, cuyo estudio confirmó una Hiperplasia Suprarrenal Congénita y cuya ecografía demostró una vagina dilatada con contenido liquido correspondiendo a un hidrocolpos neonatal. Abstract in english Hydrocolpos and hydrometrocolpos is a condition characterized by a cystic dilatation od the vagina and/or uterus with accumulation of fluid as a result of congenital vaginal obstructions. It can be of secretory or urinary types, the last one when a vagino-vesical communication develops such as a sin [...] us or chloaca. Other causes are vaginal septum, imperforated hymen. Clinical Case: Ten day old newborn, 46 XX with genital virilization (Prader IV) confirmed as due to Congenital Adrenal Hyperplasia, sonogram showed dilated vagina with fluid content due to neonatal hydrocolpos. Conclusion: It is important to maintain a high index of suspicion when a female newborn shows urogenital sinus, chloaca, genital virilization or imperforated hymen, as well as a female newborn with an abdominal mass. Diagnostic test of choice is a sonogram. Evaluation must be completed by a multidisciplinary team, including urology, endocrinology and pediatric gynecology for optimal patient management.

CAROLINA, GARFIAS VON F; ANTONIO, BARRERA N; RICARDO, ZUBIETA A; FRANCISCA, UGARTE P.

374

Differentiation of Lactobacillus Species by Molecular Typing  

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A total of 64 type, reference, clinical, health food, and stock isolates of microaerophilic Lactobacillus species were examined by restriction fragment length polymorphisms. Of particular interest were members of six of the eight species most commonly recovered from the vaginas of healthy premenopausal women, namely, Lactobacillus jensenii, L. casei, L. rhamnosus, L. acidophilus, L. plantarum, and L. fermentum. Six main groupings were identified on the basis of ribotyping. This technique was ...

Zhong, Wei; Millsap, Kevin; Bialkowska-hobrzanska, Hanna; Reid, Gregor

1998-01-01

375

Acid Production by Vaginal Flora In Vitro Is Consistent with the Rate and Extent of Vaginal Acidification  

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Perinatally, and between menarche and menopause, increased levels of estrogen cause large amounts of glycogen to be deposited in the vaginal epithelium. During these times, the anaerobic metabolism of the glycogen, by the epithelial cells themselves and/or by vaginal flora, causes the vagina to become acidic (pH ?4). This study was designed to test whether the characteristics of acid production by vaginal flora in vitro can account for vaginal acidity. Eight vaginal Lactobacillus isolates f...

Boskey, E. R.; Telsch, K. M.; Whaley, K. J.; Moench, T. R.; Cone, R. A.

1999-01-01

376

Liquen plano oral y síndrome vulvovaginal-gingival: A propósito de un caso Lichen planus and vulvovaginal-gingival syndrome: Clinical case  

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El liquen plano es una enfermedad mucocutánea crónica común, que afecta habitualmente a la mucosa oral, pero que en ocasiones otras mucosas como la vaginal pueden también afectarse. Sin embargo, la afectación concomitante de las mucosas oral y vaginal, conocida como síndrome vulvovaginal-gingival del liquen plano es una manifestación poco común, caracterizada por erosión y descamación en la vulva, vagina y encías. Debido a la posibilidad de afectación de otras mucosas así como la...

Alonso Rosado, A.; Herna?ndez Herna?ndez, E.; Mateos Rodri?guez, R.; Pe?rez Go?mez, R. M.; Bascones Marti?nez, A.

2010-01-01

377

Ovarian carcinoma producing parathyroid hormone-related protein causing hypercalcemia and metastatic calcification detected on 18F-FDG PET-CT  

International Nuclear Information System (INIS)

Hypercalcemia is associated with gynecologic malignant diseases, and cases involving various organs such as the uterus, ovaries, vulva, and vagina. This may be due to elevated levels of parathyroid hormone-related peptide (PTHrP). We describe here two cases of ovarian carcinoma simultaneously producing PTHrP that caused hypercalcemia and metastatic calcification detected on 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography-computed tomography (PET-CT). (author)

378

Pengetahuan, Sikap dan Tindakan Mahasiswi Terhadap Pemeriksaan Pap's smear di Fakultas Kesehatan Masyarakat Universitas Sumatera Utara tahun 2004  

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Salah satu pemeriksaan kesehatan yang sangat penting bagi wanita adalah pemeriksaan Pap's smear. Pap's smear merupakan pemeriksaan sitologi cairan selaput lendir rahim serta selaput lendir vagina untuk mendeteksi secara dini kanker leher rahim. Walaupun pemeriksaan Pap's smear tidak diragukan lagi manfaatnya, ada juga orang yang masih enggan melakukan pemeriksaan ini. Ternyata manfaat positif pemeriksaan kesehatan bagi seseorang belum tentu dirasakan sama untuk orang lain. Penelitian ini b...

Rachmi, Emi

2012-01-01

379

Vaginal dose point reporting in cervical cancer patients treated with combined 2D/3D external beam radiotherapy and 2D/3D brachytherapy  

International Nuclear Information System (INIS)

Background and purpose: Traditionally, vaginal dose points have been defined at the vaginal source level, thus not providing dose information for the entire vagina. Since reliable vaginal dose volume/surface histograms are unavailable, a strategy for comprehensive vaginal dose reporting for combined EBRT and BT was established and investigated. Material and methods: An anatomical vaginal reference point was defined at the level of the Posterior–Inferior Border of Symphysis (PIBS), plus two points ±2 cm (mid/introitus vagina). For BT extra points were selected for the upper vagina at 12/3/6/9 o’clock, at the vaginal surface and 5 mm depth. A vaginal reference length (VRL) was defined from ring centre to PIBS. Fifty-nine patients treated for cervical cancer were included in this retrospective feasibility study. Results: The method was applicable to all patients. Total EQD2 doses at PIBS and ±2 cm were 36.7 Gy (3.1–68.2), 49.6 Gy (32.1–89.6) and 4.3 Gy (1.0–46.6). At the vaginal surface at ring level doses were respectively 266.1 Gy (67.6–814.5)/225.9 Gy (61.5–610.5) at 3/9 o’clock, and 85.1 Gy (55.4–140.3)/72.0 Gy (49.1–108.9) at 12/6 o’clock. Mean VRL on MRI was 5.6 cm (2.0–9.4). Conclusions: With this novel system, a comprehensive reporting of vaginal doses is feasible. The present study has demonstrated large dose variations between patients observed in all parts of the vagina, resulting from different contributions from EBRT and BT

380

["Spontaneous perforation" of Douglas' pouch].  

Science.gov (United States)

"Spontaneous" perforations of Douglas's pouch are a rare complication following gynecological surgery. Three patients are reported, in which Wertheim-Meigs-operation, abdominal and vaginal hysterectomy had been performed. Laceration of the vaginal vault with opening of Douglas's pouch occurred "spontaneously" at sexual intercourse. In another patient rupture of the pelvic floor with prolapse of the intestinum was observed 7 months after colpocleisis. Small perforations may be closed through the vagina; prolapse of the intestinum requires laparotomy. PMID:11127771

Borgmann, U; Heidenreich, W

2000-01-01

 
 
 
 
381

Laparoscopic management of recurrent vesicovaginal fistula.  

Science.gov (United States)

Vesicovaginal fistula repair is most commonly undertaken via a transvaginal approach. We report a recurrent case of vesicovaginal fistula which was ultimately repaired using a laparoscopic approach. The fistula followed a hysterectomy and persisted despite two operations using the Latzko partial colpocleisis and prolonged catheterization. The fistulous tract was ultimately repaired by closing the vagina and bladder with an interposing omental flap utilizing a laparoscopic approach. PMID:10384974

Miklos, J R; Sobolewski, C; Lucente, V

1999-01-01

382

Trichomonas vaginalis is highly prevalent in adolescent girls, pregnant women, and commercial sex workers in Ndola, Zambia  

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OBJECTIVES: The aim of the study was to assess the prevalence of Trichomonas sp. infection among adolescent girls, pregnant women, and commercial sex workers in Ndola, Zambia. METHODS:: A cross-sectional study was conducted among 460 girls attending school, 307 pregnant women, and 197 commercial sex workers. Self-collected specimens from the vagina, rectum, and mouth were tested by polymerase chain amplification assays for the presence of Trichomonas vaginalis, Pentatrichomonas hominis, and T...

Crucitti, T.; Jespers, V.; Mulenga, C.; Khondowe, S.; Vandepitte, J.; Buve?, A.

2010-01-01

383

Evaluation of Reuterin Production in Urogenital Probiotic Lactobacillus reuteri RC-14?  

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Classified as a distinct species in 1980, Lactobacillus reuteri strains have been used in probiotic formulations for intestinal and urogenital applications. In the former, the primary mechanism of action of L. reuteri SD2112 (ATCC 55730) has been purported to be its ability to produce the antibiotic 3-hydroxypropionaldehyde (3-HPA), also known as reuterin. In the vagina, it has been postulated that probiotic Lactobacillus reuteri RC-14 does not require reuterin production but mediates a resto...

Cadieux, Peter; Wind, Anette; Sommer, Philip; Schaefer, Laura; Crowley, Kate; Britton, Robert A.; Reid, Gregor

2008-01-01

384

Biochemical isolation and purification of ovulation-inducing factor (OIF) in seminal plasma of llamas  

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Abstract Background The objective of the present study was to isolate and purify the protein fraction(s) of llama seminal plasma responsible for the ovulation-inducing effect of the ejaculate. Methods Semen collected from male llamas by artificial vagina was centrifuged and the seminal plasma was harvested and stored frozen. Seminal plasma was thawed and loaded onto a Type 1 macro-prep ceramic hydroxylapatite column and elution was carried out using a lineal gra...

Pierson Roger A; Leduc Yvonne A; Tj, Delbaere Louis; Ratto Marcelo H; Adams Gregg P

2011-01-01

385

Effects of Copper and Superoxide Dismutase Content of Seminal Plasma on Buffalo Semen Characteristics  

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To investigate the effects of copper and superoxide dismutase (SOD) content of seminal plasma on buffalo semen characteristics, 54 semen samples collected from buffalo bulls by a bovine artificial vagina were used. Semen characteristics (motility, viability, morphology, concentration and volume) were recorded. Seminal plasma was harvested by centrifugation and kept frozen until analysis. Seminal plasma copper content was determined by atomic absorption procedure and SOD was measured by ...

Eghbali, M.; Alavi-shoushtari, S. M.; Asri Rezaii, S.

2008-01-01

386

Proteínas do plasma seminal de caprinos relacionadas com o índice pluviométrico e a qualidade do sêmen Proteins of goat seminal plasma related with precipitation index and semen quality  

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O objetivo deste estudo foi identificar as proteínas do plasma seminal de caprinos da raça Alpina Americana criados na região Nordeste do Brasil que estão relacionadas ao índice pluviométrico e à qualidade do sêmen. O sêmen foi obtido pelo método de vagina artificial a partir de três reprodutores e foi avaliado quanto aos parâmetros macroscópicos e microscópicos. O perfil de proteínas do plasma seminal foi realizado por eletroforese bidimensional. Os parâmetros volume do sême...

Andreia Fernandes de Souza; Maria da Conceição Gomes Leitão; André Mariano Batista; Ana Lúcia Figueiredo Porto; José Luiz de Lima Filho; Maria Madalena Pessoa Guerra

2009-01-01

387

ADIÇÃO DO PLASMA SEMINAL AO SÊMEN OVINO DESCONGELADO  

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The considerable variability in constituents of seminal plasma could explain the particular differences in responses to freezing and in fertility rates after artificial insemination in ovines. This study assessed the effect of a pool of concentrated seminal plasma on ovine semen after thawing. Ejaculates of 1 2 Santa Inês rams were collected using an artificial vagina, diluted in Tris/egg yolk /glycerol and frozen in a semen and embryo freezer. After thawing, sperms were incubated using conc...

LIANA VIEIRA ROCHA; CLAUDIO ANDRES REATAMAL; CÉLIA RAQUEL QUIRINO; ANGELO BURLA DIAS

2011-01-01

388

Evaluación económica y efectos en la reproducción porcina de tres tipos de pipetas usadas para I. A.  

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La vagina y cerviz de las cerdas son estimuladas físicamente durante la inseminación. Este contacto puede afectar características reproductivas tales como el transporte espermático y el proceso de ovulación. En el presente trabajo se evaluaron desde el punto de vista económico y reproductivo, tres tipos de pipetas utilizadas para I. A. de cerdas de diferente material y forma. Se utilizaron 120 animales multíparos asignados de acuerdo a su orden de entrada al celo, en forma sucesiva a u...

Eda, J. Castau F.; Orihuela, A.

2004-01-01

389

Dystopic dysplastic kidney with ectopic ureter: improved localization by fusion of MR urography and 99mTc-DMSA SPECT datasets  

International Nuclear Information System (INIS)

We report a 12-year-old girl with a long history of constant urinary dribbling and apparently only a left kidney. Using a multimodality approach involving the fusion of MR urography and 99mTc-dimercaptosuccinic acid (DMSA) SPECT datasets, it was finally possible to exactly localize the very small dystopic, dysplastic right kidney and its ectopic ureter draining into the vagina. (orig.)

390

Morfologia e morfometria do oviduto de codornas Nothura maculosa Morphology and morphometry of Nothura maculosa quail oviduct  

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Este estudo teve por finalidade descrever o oviduto de codornas. Foram utilizadas 20 codornas na fase reprodutiva. Avaliaram-se os comprimentos do infundíbulo, do magno, do istmo, do útero, da vagina e o número de pregas no magno e no istmo. Para o estudo histológico, coletaram-se fragmentos do oviduto, os quais foram fixados em Bouin, destinados à rotina histológica e corados pela técnica de Hematoxilina-Eosina. O infundíbulo apresentou pregas longitudinais e oblíquas, revestidas po...

Carime Moraes; Silvana Martinez Baraldi-Artoni; Daniela Oliveira; Maria Rita Pacheco; Lizandra Amoroso; Vanessa Sobue Franzo

2007-01-01

391

Uterus didelphys with partial vaginal septum and distal vaginal agenesis: an unusual anomaly  

International Nuclear Information System (INIS)

Complex malformations of female genital tract are not so common. Their correct identification is of paramount importance for appropriate management. A thorough knowledge of embryology, pre-operative imaging with MRI and examination under anaesthesia is essential to identify accurately the constellation of anomalies and to plan appropriate management. This case reports the coexistence of Mullerian abnormality with vaginal agenesis in an 18 years old girl which was managed by dissecting the lower half of vagina and pull-through vaginoplasty. (author)

392

Tumor de la vulva, vulvectomía radical / Vulvar tumor, total vulvectomy  

Scientific Electronic Library Online (English)

Full Text Available SciELO Cuba | Language: Spanish Abstract in spanish Los tumores de la vulva no son una rareza entre los cánceres que afectan a las féminas, pero tampoco son de los más frecuentes. Se presenta el caso de una mujer de 59 años, que en el año 2000 se le diagnostica carcinoma epidermoide del clítoris, en 2004 se vuelve a intervenir por recidiva tumoral, y [...] en 2009 acude a nuestra consulta nuevamente y es cuando se decide realizarle vulvectomía y resección de vagina y todo el sistema ginecológico. Concluyó la intervención con una talla vesical extraperitoneal. El tumor se extiende hasta la porción inicial de la vagina y uretra. Se trata de un tumor maligno, bien diferenciado, que se ha comportado en una forma no habitual, con recidivas locales, cuando en apariencia el tumor había sido resecado en toda su extensión, y en esta última oportunidad, a pesar de ser un estadio avanzado, no hemos encontrado metástasis ni multicentricidad del tumor. La evolución posoperatoria fue sin complicaciones y se dio de alta al quinto día. Abstract in english The vulvar tumors are not uncommon among the different types of cancer involving females, but neither are the more frequent ones. This is the case of a female aged 59 that in 2000 is diagnosed with epidermoid carcinoma of clitoris, in 2004 is re-operated on by tumor relapse, and in 2009 she came aga [...] in to our consultation and a vulvectomy, vagina resection and all gynecological system are carried out. Intervention concluded with an extraperitoneal vesical cutting. The tumor extends up to the initial portion of vagina and urethra. It is a malignant and well-differentiated tumor behaved in non habitual way with local relapses, when apparently the tumor was resected in all its extent, and in this last change, despite and advanced stage, there were neither tumor metastases nor multi-centralization. The postoperative course was free of complications receiving the discharge at fifth day.

Asbel Alfredo, Vicente de la Cruz; Maribel Lissette, Vicente Medina; Ada Hilda, de la Concepción de la Peña.

2011-09-01

393

Common lesions in the female reproductive tract of dogs and cats.  

Science.gov (United States)

Reproductive lesions are commonly seen in small animal practice. Lesions in the ovaries, uterus, and vagina may seriously influence normal reproductive capacity of dogs and cats and may put at risk the general health of the patients. The objective of this article is to give the veterinary practitioner a current and concise guide to the clinical signs, intraoperative changes, diagnosis, and treatment/management of lesions in the reproductive tract of the bitch and queen commonly seen in practice. PMID:22482818

Ortega-Pacheco, Antonio; Gutiérrez-Blanco, Eduardo; Jiménez-Coello, Matilde

2012-05-01

394

A Giant Gartner Duct Cyst Originating from the Uterine Cervix and Adjacent Myometrium: A Case Report  

International Nuclear Information System (INIS)

Gartner duct cysts are relatively common congenital cysts in the anterolateral wall of the vagina. Most are small (less than 2 cm) and asymptomatic, but larger cysts may cause problems. We report a rare case of a giant Gartner duct cyst (7 cm) originating from the right lateral portion of the uterine cervix and adjacent myometrium. It appeared as an exophytic multiseptated cystic mass containing different density fluids on CT

395

Candida albicans Adhesion to and Invasion and Damage of Vaginal Epithelial Cells: Stage-Specific Inhibition by Clotrimazole and Bifonazole?  

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Clotrimazole and bifonazole are highly effective antifungal agents against mucosal Candida albicans infections. Here we examined the effects of low levels of clotrimazole and bifonazole on the ability of C. albicans to adhere, invade, and damage vaginal epithelial cells. Although adhesion and invasion were not affected, damage was greatly reduced upon azole treatment. This clearly indicates that low levels of azoles influence specific activities of C. albicans during distinct stages of vagina...

Wa?chtler, Betty; Wilson, Duncan; Hube, Bernhard

2011-01-01

396

Microbicides 2006 conference  

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Abstract Current HIV/AIDS statistics show that women account for almost 60% of HIV infections in Sub-Saharan Africa. HIV prevention tools such as male and female condoms, abstinence and monogamy are not always feasible options for women due to various socio-economic and cultural factors. Microbicides are products designed to be inserted in the vagina or rectum prior to sex to prevent HIV acquisition. The biannual Microbicides conference took place in Cape Town, South Africa f...

McGowan Ian; Delany Sinead; Shattock Robin; Ramjee Gita; Morar Neetha; Gottemoeller Megan

2006-01-01

397

Cervical Cancer – A Review Article  

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Cervical Cancer is malignant Carcinoma type of cancer originate in cervix region. The cervix is the narrow portion of the uterus where it joins with the top of the vagina. Most cervical cancers are squamous cell carcinomas, arising in the squamous (flattened) epithelial cells that line the cervix. Adenocarcinoma, arising in glandular epithelial cells is the second most common type. Very rarely, cancer can arise in other types of cells in the cervix. Cancer refers to a class of diseases in whi...

Gunjan Jadon

2012-01-01

398

DNA Fingerprinting of Lactobacillus crispatus Strain CTV-05 by Repetitive Element Sequence-Based PCR Analysis in a Pilot Study of Vaginal Colonization  

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Lactobacillus crispatus is one of the predominant hydrogen peroxide (H2O2)-producing species found in the vagina and is under development as a probiotic for the treatment of bacterial vaginosis. In this study, we assessed whether DNA fingerprinting by repetitive element sequence-based PCR (rep-PCR) can be used to distinguish the capsule strain of L. crispatus (CTV-05) from other endogenous strains as well as other species of vaginal lactobacilli. Vaginal and rectal lactobacilli were identifie...

Antonio, May A. D.; Hillier, Sharon L.

2003-01-01

399

Rebuilding life: A journey through the lives of women who have endured and been treated for obstetric fistula in Tanzania  

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Introduction Obstetric fistula is a birthing injury which leaves a woman leaking urine and/or faeces from her vagina. This occurs when there is prolonged obstructed labour, and emergency obstetric care is unavailable. It disproportionately affects poor, uneducated women from rural areas and makes them even more marginalized after they have suffered the injury. The constant smell from leaking subjects them to rejection from society, they are unable to work, and are ashamed of their condition....

Irani, Julia Noshir

2012-01-01

400

BREED DIFFERENCES IN SEVERAL CHARACTERISTICS OF BULL FROZEN-THAWED SPERM  

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A number of factors influencing bull fertility are identified including scrotal circumference, sperm morphology, motility, mating ability, age, body condition and the breed of the bull. This study was aimed at comparison of some sperm characteristics in Czech Fleckvieh (n= 8) and Holstein (n= 8) bulls at the age of 1 to 6 years. Samples of ejaculate were obtained from each bull using an artificial vagina. After determination of pathologic sperm (staining with Congo red, Bromothymol blue and J...

Makarevich, Alexander V.; Eliška Špaleková; Lud?k Stádník; Elena Kubovi?ová; František Louda

2013-01-01

 
 
 
 
401

Histological Study of Cervix Uteri in Caspian Miniature Horse  

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Problem statement: Uterine cervix which separates the uterus from the vagina, shows remarkable anatomical and histological differences among mammalian species. Since no cleared observations have been found in regards with the Caspian miniature horses? cervix, the aim of the present study was to supplement this missing information which could be helpful for providing a stricter basis in detecting reproductive diseases and abnormalities in this valuable species. Approach: Cervice...

Rezaian, M.; Hamedi, S.

2010-01-01

402

Hidrocolpos e hidrometrocolpos neoanatal: a propósito de un caso clínico Neonatal hydrocolpos and hydrometrocolpos: a clinical case  

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Full Text Available El Hidrocolpos e Hidrometrocolpos es una condición caracterizada por dilatación quística de la vagina y/o del útero, con acumulación de líquido como resultado de obstrucciones vaginales congénitas. Puede ser de tipo secretorio o urinario, este último ocurre cuando existe comunicación vagino-vesical, como en el seno urogenital o anomalía tipo cloaca. Otras causas son septo vaginal, himen imperforado, malformación tipo cloaca y senourogenital. Caso: Recién nacida de 10 días, 46 XX, con virilización de genitales grado IV de Prader, cuyo estudio confirmó una Hiperplasia Suprarrenal Congénita y cuya ecografía demostró una vagina dilatada con contenido liquido correspondiendo a un hidrocolpos neonatal.Hydrocolpos and hydrometrocolpos is a condition characterized by a cystic dilatation od the vagina and/or uterus with accumulation of fluid as a result of congenital vaginal obstructions. It can be of secretory or urinary types, the last one when a vagino-vesical communication develops such as a sinus or chloaca. Other causes are vaginal septum, imperforated hymen. Clinical Case: Ten day old newborn, 46 XX with genital virilization (Prader IV confirmed as due to Congenital Adrenal Hyperplasia, sonogram showed dilated vagina with fluid content due to neonatal hydrocolpos. Conclusion: It is important to maintain a high index of suspicion when a female newborn shows urogenital sinus, chloaca, genital virilization or imperforated hymen, as well as a female newborn with an abdominal mass. Diagnostic test of choice is a sonogram. Evaluation must be completed by a multidisciplinary team, including urology, endocrinology and pediatric gynecology for optimal patient management.

CAROLINA GARFIAS VON F

2011-04-01

403

Experimental transmission of Trypanosoma cruzi through the genitalia of albino mice  

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Trypanosoma cruzi is usually transmitted by contact with the excreta of infected Triatominae; among non-vectorial infections, direct transmission through coitus has been proposed. We investigated this possibility by instilling, through the external meatus of the vagina and the penis of previously anesthetized NMRI albino mice, blood of mice infected with strains isolated from Didelphis marsupialis (opossum, strain CO57), Rattus rattus (rat, strain CO22) and human (strain EP). Some animals wer...

2001-01-01

404

Immunoreactivities to protein gene product 9.5, neurofilament protein and neuron specific enolase in nerves in the oviduct of the sexually immature ostrich, Struthio camelus  

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The present study investigated the distribution of nerves in the oviduct of the sexually immature ostrich. The presence of protein gene product 9.5, neurofilament protein and neuron specific enolase nerve fibres were demonstrated in the infundibulum, magnum, isthmus, shell gland and vagina. Nerve fibres containing protein gene product 9.5, neuron specific enolase and neurofilament protein were particularly numerous in the tunica muscularis and...

M-c, Madekurozwa

2010-01-01

405

La découverte de l'amour par Hidi Xinu. Récit caxinaua  

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Full Text Available La littérature concernant la cosmologie caxinaua est assez connue, on propose néanmoins un récit jubilatoire qui raconte la découverte de l?amour par le personnage Xidi Xinu. Ce récit évoque le désespoir des Caxinaua qui prenaient le ?vagin? pour une méchante plaie. Malgré la connaissance de leur pharmacopée, ils n?arrivaient pas à la guérir. Cependant, un jour, l?un des Caxinaua, Hidi Xinu, a vu un couple de singes copuler et a compris la fonction du vagin : le réceptacle de l?amour, cutati. EL DESCUBRIMIENTO DEL AMOR POR HIDI SHINU. UNA NARRACIÓN CASHINAHUA. Aunque la literatura sobre la cosmología cashinahua es bastante conocida, proponemos aquí una alegre narración que cuenta el descubrimiento del amor por parte del personage Hidi Shinu. Esta narración evoca el desespero de los Cashinahua, quienes tomaban la vagina por una mala herida. A pesar de sus conocimientos farmacológicos, no lograban sanarla. Sin embargo, un día, uno de los Cashinahua vio copular a una pareja de micos y comprendió la función de la vagina: el receptáculo del amor, chutati. THE DISCOVERY OF LOVE BY HIDI SHINU. A CASHINAHUA TALE. The literature of the Cashinahua mythology is quite well known, thus I present an amusing tale about the discovery of love by the character Hidi Xinu. This tale reminds us of the despair of the Cashinahua who thought the vagina to be a very severe flesh wound. Regardless of their knowledge of pharmacopoeia, they could not heal her. However, one day, Hidi Xinu saw a couple of monkeys copulate and only then did he understand the function of the vagina: the chamber of love, chutati.

1999-01-01

406

Syndrome in question  

Scientific Electronic Library Online (English)

Full Text Available SciELO Brazil | Language: English Abstract in english Vulvovaginal-gingival syndrome is characterized by erosions and desquamation of the vulva, vagina, and gingiva. We reported a case of a 32-year-old woman presenting with an 8-year history of damage to the vulval and perianal anatomy and limitation of mouth opening. The patient's symptoms were reliev [...] ed after treatment with topical tacrolimus cream.

Yinhua, Wu; Jianjun, Qiao; Hong, Fang.

2014-09-01

407

Spontaneous Rupture of the Anterior Vaginal Wall during the First Stage of Labour  

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The risk of uterine rupture during attempted trial of labor after caesarean delivery (TOLAC) is well documented. However, vaginal rupture (in the absence of obstructed labour) is exceptionally uncommon. Below is described the rare case of a 37-year-old multiparous woman attempting TOLAC, who suffered a vaginal—rather than uterine—rupture, during the first stage of spontaneous labour. This case is an important reminder to obstetricians that concealed ruptures of both the vagina and uterus ...

Schultz, Meleesa Joy; Nanda, Triveni

2012-01-01

408

Placenta accrete treated with uterine arterial embolization (case report)  

International Nuclear Information System (INIS)

Objective: To investigate the possibility of interventional treatment of placenta accrete. Methods: One patient with placenta accrete was treated with uterine arterial infusion of cef and MTX followed by embolization. Results: Her placenta discharged through vagina at the 27 th day after uterine arterial embolization. No remnant was found in the uterine by Doppler imaging. The patient uneventfully recovered. Conclusions: Interventional therapy with uterine arterial embolization is a new and reliable method for treatment for placenta accrete

409

Utility of vaginal and rectal contrast medium in MRI for the detection of deep pelvic endometriosis  

International Nuclear Information System (INIS)

To study the sensitivity of MRI performed utilising vaginal and rectal opacification with ultrasound gel in the detection of deep pelvic endometriosis. This was a prospective monocentric study. All patients evaluated by the gynaecologist for pelvic pain, endometriosis or infertility were included. Axial and sagittal T2-weighted images were performed both with and without vaginal and rectal opacification with ultrasound gel. Three radiologists, all blinded, interpreted the images with a minimum of 15 days between the two readings. MRI performance with and without vaginal and rectal opacification was evaluated by calculating sensitivity, specificity and both positive and negative predictive values. Seventy-eight patients were included. Among these, 31 patients had deep pelvic endometriosis of which 24 were confirmed by laparoscopy. Seventy-six locations of deep pelvic endometriosis were discovered on MRI. For the three reviewers there was a significant improvement in sensitivity between pre- and post-contrast MRI (p < 0.0002). Opacification of the vagina and rectum significantly improved the sensitivity of MRI for the detection of deep pelvic endometriosis by expanding the vagina and rectum, thus allowing better delineation of the pelvic organs. This was especially apparent for lesions localised to the vagina and rectovaginal septum. (orig.)

410

Pre-operative, post-operative and exclusive irradiation of endometrial adenocarcinoma  

International Nuclear Information System (INIS)

Purpose: Surgery is the golden standard of treatment of endometrial carcinoma. The risk of central or vaginal recurrences justifies adjuvant treatment. Methods: Brachytherapy for endometrial adenocarcinoma is given commonly as pre- or post-operative treatment. In case of medical contro-indications for surgery brachytherapy can be applied as the only tratment. Experience of the anticancer center Alexis Vautrin in Nancy of the years 1975 to 1988 is evaluated. Iridium-192 low-dose-rate (LDR) wires were used. Results: Pre-operative brachytherapy was given with a vaginal mould applicator to 580 patients. The dose was 50 Gy at 0.5 cm below the surface of the vagina. The locoregional control rate was 93% after 5 years and the 5-year survival 82%. 139 patients received radiotherapy alone and no surgery. LDR-brachytherapy was given the upper third of the vagina and endometrium with an 'umbrella' applicator. The locoregional control rate was 83% after 5 years and the survival rate 55%. 117 patients received a post-operative brachytherapy of the vagina. The locoregional control rate was 93% after 10 years and the survival rate 65%. Conclusion: A pre- and post-operative radiotherapy results in a reduction of the vaginal relapse rate. The LDR afterloading technique with primary radiotherapy of endometrial adenocarcinoma leads to a locoregional control slightly interior. The treatment results compare favourably with the best of the literature. (orig.)re. (orig.)

411

Recurrent microdeletion at 17q12 as a cause of Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome: two case reports  

Science.gov (United States)

Background Mayer-Rokitansky-Kuster-Hauser syndrome (MRKH) consists of congenital aplasia of the uterus and the upper part of vagina due to anomalous development of Müllerian ducts, either isolated or associated with other congenital malformations, including renal, skeletal, hearing and heart defects. This disorder has an incidence of approximately 1 in 4500 newborn girls and the aetiology is poorly understood. Methods and Results we report on two patients affected by MRKH syndrome in which array-CGH analysis disclosed an identical deletion spanning 1.5 Mb of genomic DNA at chromosome 17q12. One patient was affected by complete absence of uterus and vagina, with bilaterally normal ovaries, while the other displayed agenesis of the upper part of vagina, right unicornuate uterus, non cavitating rudimentary left horn and bilaterally multicystic kidneys. The deletion encompassed two candidate genes, TCF2 and LHX1. Mutational screening of these genes in a selected group of 20 MRKH females without 17q12 deletion was negative. Conclusion Deletion 17q12 is a rare albeit recurrent anomaly mediated by segmental duplications, previously reported in subjects with developmental kidney abnormalities and diabetes. The present two patients expand the clinical spectrum associated with this imbalance and suggest that this region is a candidate locus for a subset of MRKH syndrome individuals, with or without renal defects. PMID:19889212

Bernardini, Laura; Gimelli, Stefania; Gervasini, Cristina; Carella, Massimo; Baban, Anwar; Frontino, Giada; Barbano, Giancarlo; Divizia, Maria Teresa; Fedele, Luigi; Novelli, Antonio; Bena, Frederique; Lalatta, Faustina; Miozzo, Monica; Dallapiccola, Bruno

2009-01-01

412

Morphology and morphometry of the reproductive system of female Saguinus midas (Linnaeus, 1758).  

Science.gov (United States)

In this article, the reproductive system's morphology of three young animals of the species Saguinus midas, from the bauxite mine in Paragominas, is described. The specimens were fixed and preserved in a solution of 10% aqueous formaldehyde, followed by dissection, measurement of the genital organs (uterus, vagina, ovaries, and uterine tubes), and histological processing. The vulva is delimited by the labia, with a clitoris. It is lined by keratinized stratified squamous epithelium with sebaceous glands of holocrine secretion. The vagina is an elongated tube with an average length of 26 mm and diameter of 1 mm, presenting a non-keratinized squamous epithelium, disposed between the vestibule of the vagina and cervix, the latter being relatively short. The uterus is simple, has globular shape and is located in the caudal portion of the abdominal cavity, with an average length of 14 mm and average width of 7 mm. It is formed by vascular and serous layers of muscles, and undergoes a bifurcation to form two structures on the bottom of blind sac. The uterine tubes are long and convoluted with an average length of 35 mm (right) and 36 mm (left), consisting of loose connective tissue and muscle layer lined by simple ciliated columnar epithelium. The ovaries are large and ellipsoid with smooth surface. Histologically, one animal showed ovulation fosse. PMID:22131285

Monteiro, Nathaly Cristine Da Silva; De Lima, Ana Rita; De Carvalho, Ana Flávia; De Carvalho Garcia, Rafael; Therrier, Joanne; Souza, Ana Carla Barros; Pereira, Luiza Correia; Branco, Erika

2012-06-01

413

Tuboovarian abscess as primary presentation for imperforate hymen.  

Science.gov (United States)

Objective. Imperforate hymen represents the extreme in the spectrum of hymenal embryological variations. The archetypal presentation in the adolescent patient is that of cyclical abdominopelvic pain in the presence of amenorrhoea. We reported a rare event of imperforate hymen presenting as a cause of tuboovarian abscess (TOA). Case Study. A 14-year-old girl presented to the emergency department complaining of severe left iliac fossa pain. It was her first episode of heavy bleeding per vagina, and she had a history of cyclical pelvic pain. She was clinically unwell, and an external genital examination demonstrated a partially perforated hymen. A transabdominal ultrasound showed grossly dilated serpiginous fallopian tubes. The upper part of the vagina was filled with homogeneous echogenic substance. Magnetic resonance imaging (MRI) demonstrated complex right adnexa mass with bilateral pyo-haemato-salpinges, haematometra, and haematocolpos. In theatre, the imperforate hymen was opened via cruciate incision and blood was drained from the vagina. At laparoscopy, dense purulent material was evacuated prior to an incision and drainage of the persistent right TOA. Conclusion. Ideally identification of imperforate hymen should occur during neonatal examination to prevent symptomatic presentation. Our case highlights the risks of late recognition resulting in the development of sepsis and TOA. PMID:24822139

Ho, Jeh Wen; Angstetra, D; Loong, R; Fleming, T

2014-01-01

414

La Estimulación Vibratoria del Pene (EVP, Alternativa Novedosa y no Invasiva para la Obtención de Semen en Primates y otras Especies Animales  

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Full Text Available A nivel mundial en diversas especies animales domésticas y silvestres, se lleva a cabo la colecta y evaluación de las características seminales con distintos objetivos, como son el conocimiento preliminar de la biología reproductiva (andrología, criopreservación de gametos, inseminación artificial entre otros. Para obtener semen se dispone de diversas técnicas; entre estos están; la electroeyaculación por sonda bipolar rectal o por estimulación directa del pene, la masturbación, la automasturbación, la punción epidídimal, el lavado vaginal post-eyaculación, vagina artificial y la Estimulación Vibratoria del Pene (EVP. Esta ultima (EVP una de las más novedosas y no invasivas que últimamente ha ganado terreno con el FertiCare® personal vibrator, ya que no representa mayores consecuencias a los animales muestreados, su adquisición no es costosa comparada con los electroeyaculadores, apenas mide 20cm de largo y pesa 285gr, y como mayor ventaja en cuanto a viabilidad y concentración de espermatozoides, la cual es mayor en aquellos métodos no invasivos como la masturbación, la vagina artificial y la estimulación vibratoria del pene, claro que esta ultima tiene una gran ventaja y es el control para evitar la contaminación por bacterias o aditivos (talcos o resinas de látex en vaginas artificiales del semen, por consiguiente la calidad de la muestra seminal obtenida es mucho mayor.

Robin Poches-Franco

2010-10-01

415

Transvaginal perineal body repair for low rectocele.  

Science.gov (United States)

We describe our technique of low rectocele repair which is based on the approximation and lifting of the laterally displaced perineal bodies (PBs) using the Tissue Fixation System, a 7-mm-wide tensioned macropore polypropylene sling. In low rectocele, the PB between the rectum and vagina is thinned and laterally displaced but still attached to the deep transverse perineal (DTP) muscle. Our technique is described with the aid of a video. The vagina and rectum are dissected off the laterally displaced PBs. The DTP attachment of each PB to the descending ramus is identified per rectum. A tunnel is created in the DTP on both sides to insert the polypropylene mesh attached to an anchor. The loop of tape between the anchors is shortened via the one-way system at the base of the anchor to elevate the inferolaterally displaced PBs to a more medial position. This is infiltrated by collagen over time, creating a "neo-central tendon." The musculofascial layer of the rectum, the vagina, and superficial layers of the PBs are approximated. Our cure rate for low rectocele repair was in excess of 90 %, even with an early version of this procedure. Our method differs from rectocele repair with large mesh in that it precisely mimics the damaged structure and uses only very short thin strips of tape to approximate and reinforce PBs weakened by birth injury and age. PMID:23417773

Petros, P; Inoue, H

2013-08-01

416

Recurrent endometrial cancer: patterns of recurrent disease and assessment of prognosis  

International Nuclear Information System (INIS)

Aim: To evaluate patterns of disease and identify factors predicting outcome in patients presenting with recurrent endometrial adenocarcinoma following primary surgery. Materials and methods: A retrospective review was performed of the imaging and clinical data in 86 patients (median age 66 years, range 42-88 years) presenting with recurrent endometrial adenocarcinoma following primary surgery. Results: Following primary surgery recurrent disease occurred within 2 years in 64% and within 3 years in 87%. Relapse was seen within lymph nodes in 41 (46%), the vagina in 36 (42%) the peritoneum in 24 (28%) and the lung in 21 (24%). Unusual sites of disease included spleen, pancreas, rectum, muscle and brain. Univariate survival analysis showed the factors significant for poor outcome were: multiple sites of disease, liver and splenic disease, haematogenous, peritoneal and nodal spread, poorly differentiated tumour, and early relapse. The presence of disease within the vagina, bladder or lung was not associated with poor prognosis. Multivariate analysis identified multiple sites of disease, liver and splenic metastases to be independent predictors of poor outcome. Conclusion: The most frequently observed sites of relapse are: lymph nodes, vagina, peritoneum and lung. Significant predictors of poor outcome in recurrent disease are multiple sites of disease and liver and splenic metastases

417

Important differences in nitric oxide synthase activity and predominant isoform in reproductive tissues from human and rat  

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Full Text Available Abstract For the extrapolation of data obtained from experimental animals to the human situation, it is important to know the similarities and differences between human and animal species. Some important characteristics of nitric oxide synthase (NOS in myometrium and vagina from human and rat were compared. NOS-activity was measured by the formation of 14C-citrulline from 14C-arginine and the expression of NOS isoforms was examined by Western blotting. NOS activity in human uterus and vagina was significantly lower than in the tissues from rat. In contrast to the rat where NOS activity was predominantly found in the cytosolic fractions, NOS activity in particulate and cytosolic fractions from both human myometrium and vagina was similar. Data from Western blots confirmed that eNOS and nNOS isoforms were concentrated in the particulate and cytosolic fractions, respectively. Estrogen treatment of rats resulted in a down regulation of uterine cytosolic NOS activity. A down regulation of NOS in the cytosolic fraction was also seen in the human pregnant myometrium as compared with the nonpregnant myometrium. The vaginal NOS activity was considerably higher than the uterus in both species. In spite of some clear-cut qualitative and other differences between human and rat tissues, there are some interesting similarities. Downregulation in pregnancy of human uterine NOS is probably due to, at least in part, the influence of estrogen and progesterone.

Al-Hijji J

2003-02-01

418

Actividad antimicrobiana e irritabilidad vaginal y dérmica de extractos acuosos de hojas secas de Solanum americanum Mill.  

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Full Text Available INTRODUCCIÓN: Solanum americanum Mill. (yerba mora es usada de forma tradicional para el tratamiento de las úlceras en la piel, se utiliza además como antiinflamatorio y antiséptico en enfermedades de la piel y en cérvico-vaginitis. Sin embargo, existen pocos estudios preclínicos que validen su uso. OBJETIVO: evaluar la actividad antimicrobiana, la irritabilidad vaginal y dérmica de 2 decocciones de hojas secas de Solanum americanum Mill. MÉTODOS: se prepararon 2 extractos acuosos de: a hojas secas al 20 % y se evaluó la actividad antimicrobiana mediante el método de difusión en agar, frente a los microorganismos Candida albicans, Escherichia coli, Klebsiella pneumoniae y Salmonella thyphymurium; así como la irritabilidad en vagina de coneja por el método de Draize. b hojas secas al 30 % y se determinó la irritabilidad en piel por el método de Draize en conejos. RESULTADOS: se obtuvo con la decocción de hojas secas al 20 % un halo de inhibición del crecimiento de 15,5 mm con el microorganismo Candida albicans, no hubo halo de inhibición con los otros microorganismos estudiados, se observó una irritabilidad vaginal mínima y no hubo eritema y edema en la piel de los animales con la decocción de hojas secas al 30 %. CONCLUSIONES: la decocción de hojas secas de S. americanum mostró actividad antimicrobiana frente a C. albicans y no frente a los otros microorganismos, presentó irritabilidad mínima en vagina y clasificó como no irritante en piel, por lo que pueden ser empleadas en afecciones provocadas por C. albicans en piel y en vagina.

María Julia Martínez Guerra

2009-03-01

419

Pre-operative, post-operative and exclusive irradiation of endometrial adenocarcinoma  

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Purpose: Surgery is the golden standard of treatment of endometrial carcinoma. The risk of central or vaginal recurrences justifies adjuvant treatment. Methods: Brachytherapy for endometrial adenocarcinoma is given commonly as pre- or post-operative treatment. In case of medical contro-indications for surgery brachytherapy can be applied as the only tratment. Experience of the anticancer center Alexis Vautrin in Nancy of the years 1975 to 1988 is evaluated. Iridium-192 low-dose-rate (LDR) wires were used. Results: Pre-operative brachytherapy was given with a vaginal mould applicator to 580 patients. The dose was 50 Gy at 0.5 cm below the surface of the vagina. The locoregional control rate was 93% after 5 years and the 5-year survival 82%. 139 patients received radiotherapy alone and no surgery. LDR-brachytherapy was given the upper third of the vagina and endometrium with an 'umbrella' applicator. The locoregional control rate was 83% after 5 years and the survival rate 55%. 117 patients received a post-operative brachytherapy of the vagina. The locoregional control rate was 93% after 10 years and the survival rate 65%. Conclusion: A pre- and post-operative radiotherapy results in a reduction of the vaginal relapse rate. The LDR afterloading technique with primary radiotherapy of endometrial adenocarcinoma leads to a locoregional control slightly interior. The treatment results compare favourably with the best of the literature. (orig.)

Pernot, M. (Centre Alexis Vautrin, Vandoeuvre les Nancy (France)); Hoffstetter, S. (Centre Alexis Vautrin, Vandoeuvre les Nancy (France)); Peiffert, D. (Centre Alexis Vautrin, Vandoeuvre les Nancy (France)); Guillemin, F. (Centre Alexis Vautrin, Vandoeuvre les Nancy (France)); Carolus, J.M. (Centre Alexis Vautrin, Vandoeuvre les Nancy (France)); Verhaeghe, J.L. (Centre Alexis Vautrin, Vandoeuvre les Nancy (France)); Luporsi, E. (Centre Alexis Vautrin, Vandoeuvre les Nancy (France)); Beckendorf, V. (Centre Alexis Vautrin, Vandoeuvre les Nancy (France))

1994-06-01

420

Transcervical artificial insemination in dogs and cats: review of the technique and practical aspects.  

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The technique of transcervical catheterization for artificial insemination has gained practical importance over the last 3 and 1 decades in bitches and queens, respectively. The vagina of both species has a thickening of the dorsal aspect called dorsal medial fold, which restricts the lumen of the paracervix, making catheterization of the cervix difficult both with manual and endoscopic techniques. Manual catheters have been used initially in the bitch and are now gradually being replaced by rigid endoscopy through the adaptation of human cystoscopes and ureteroscopes. Cystoscopes provide excellent imaging of the vagina, but cervical catheterization is more difficult due to the oblique 30° viewing angle of its telescope and may not be long enough to catheterize large size bitches. Ureteroscopes allow an acceptable view of the vaginal mucosa and offer advantages such as the possibility to catheterize the cervix of bitches of all body sizes, manipulate the cervical tubercle when the external cervical os is not visible, offer a better visualization of the cervix using the shunt (a large Foley catheter which allows insufflation and distention of the vagina). Feline cervical catheterization has been achieved with three different types of catheters; the last one, developed following careful anatomical studies of how the feline vaginal lumen changes during estrus, allows cervical catheterization thanks to digital manipulation of the cervix through the rectum. PMID:25277433

Romagnoli, S; Lopate, C

2014-10-01

 
 
 
 
421

Cervical Cancer – A Review Article  

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Full Text Available Cervical Cancer is malignant Carcinoma type of cancer originate in cervix region. The cervix is the narrow portion of the uterus where it joins with the top of the vagina. Most cervical cancers are squamous cell carcinomas, arising in the squamous (flattened epithelial cells that line the cervix. Adenocarcinoma, arising in glandular epithelial cells is the second most common type. Very rarely, cancer can arise in other types of cells in the cervix. Cancer refers to a class of diseases in which a cell or a group of cells divide and replicate uncontrollably, intrude into adjacent cells and tissues (invasion and ultimately spread to other parts of the body than the location at which they arose (metastasis (National Cancer Institute 2009. In cervical cancer, (cancer of the uterine cervix, cancer develops in the tissues of the cervix, which is a part of the female reproductive system. The cervix connects the upper body of the uterus to the vagina. The endocervix (the upper part which is close to the uterus is covered by glandular cells, and the ectocervix (the lower part which is close to the vagina is covered by squamous cells. The transformation zone refers to the place where these two regions of the cervix meet (American Cancer Society 2009.

Gunjan Jadon

2012-07-01

422

New species of Demidospermus (Monogenea: Dactylogyridae) of pimelodid catfish (Siluriformes) from Peruvian Amazonia and the reassignment of Urocleidoides lebedevi Kritsky and Thatcher, 1976.  

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Three new species of Demidospermus Suriano, 1983 were found in mixed infections on the gills of 4 pimelodid catfish collected in the Amazon River basin around Iquitos, Peru, namely, Demidospermus peruvianus n. sp. from Pimelodus ornatus Kner, Pimelodus blochii Valenciennes, Pimelodus sp. (type host), and an unidentified pimelodid. Demidospermus peruvianus n. sp. (type host, Pimelodus sp.) is characterized by the presence of the male copulatory organ with 2 lateral, thickened projections, and the vagina with a loop at its middle. Demidospermus curvovaginatus n. sp. from P. ornatus , Pimelodus sp. (type host), and Pimelodidae gen. sp. differs from its congeners by the presence of a funnel-shaped vagina directed posteriorly and a male copulatory organ with a small lateral projection at its base. Demidospermus striatus n. sp. from P. blochii and Pimelodus sp. (type host) is distinguished by a cup-shaped vagina with conspicuous ridges at the perimeter of the aperture with a short tube directed anteriorly. In addition, Urocleidoides lebedevi Kritsky and Thatcher, 1976 , a parasite originally described from the gills of Pimelodus grosskopfii (type host) from Colombia, is transferred to Demidospermus , based on morphological characters that we observed in type specimens. PMID:21506840

Mendoza-Palmero, Carlos A; Scholz, Tomáš

2011-08-01

423

Pengaruh Tepung Teripang Pasir (Holothuria Scabra Terhadap Perilaku Seksual dan Kadar Testosteron Darah Mencit (Mus musculus  

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Full Text Available Sea cucumber is generally believed as a natural material that can be used as a tonic food to increase man vitality. The aim of this study was to investigate the effect of sandfish powder on sexual behavior and blood testosterone level of male mice. Method applied in the study was laboratory experimental method. Mature male mice were treated with administration of sandfish powder with three dosage rate of steroid content (10, 30 and 50 ìg/100 g body weight during 12 days, whereas for control treatment were without hormone administration and with the metil testosterone administration. Parameters that were investigated were kissing vagina and mounting for sexual behavior and the blood testosterone level of male mice. It was found that administration of sandfish powder significantly give effect on the number of kissing vagina and mounting compared to control. Administration of 10 ìg/100 g body weight on male mice showed the highest sexual behavior with 25 kissing vagina for and 6 mounting for 30 minutes. Moreover, administration of sandfish powder increased the testosterone level in the male mice blood. This may due to the steroid contained in sandfish powder and nutrition value that increase mice libido. The study proved that the sandfish powder has a potential as a nature aphrodisiac.

Sarifah Nurjanah

2009-09-01

424

The normal genital tract of the female California sea lion (Zalophus californianus): cyclic changes in histomorphology and hormone receptor distribution.  

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Changes in reproductive tract histomorphology, and estrogen (ERalpha) and progesterone receptor (PR) expression throughout the breeding cycle were evaluated in free-ranging stranded female California sea lions (Zalophus californianus). Hormone receptor expression in the ovaries, uterus, cervix, and vagina was evaluated using an immunohistochemical technique with monoclonal antibodies. During a large portion of the cycle, ovaries contained both a corpora lutea (CL) and follicles in varying stages of development. In the periods of pupping and estrus during June and July, and in the spring morphologic features of the endometrium suggested estrogen influence. There were areas of squamous differentiation in the pseudostratified columnar epithelium of the cervix and vagina in some animals during estrus and in the spring. Estrogen receptor immunohistochemical scores were highest during pupping and estrus and in the spring and lowest during embryonic diapause. Cyclic changes in uterine PR expression throughout the cycle were minimal. Both ERalpha and PR were expressed in epithelial and stromal cells throughout the cervix and vagina, however, receptor expression was typically higher in the stroma. Stromal cell hormone receptors may play an important role in epithelial responses to circulating sex hormones. The results of this investigation add to the general knowledge of California sea lion reproduction and establish baseline information on reproductive tract hormone receptors that will aid in determining the factors involved in urogenital cancer development in sea lions. PMID:19768749

Colegrove, Kathleen M; Gulland, Frances M D; Naydan, Diane K; Lowenstine, Linda J

2009-11-01

425

Excretory urography and ultrasonography in the diagnosis of bilateral ectopic ureters in a foal  

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A 7-week-old Appaloosa filly was admitted for persistent urinary incontinence since birth. Vaginal speculum examination revealed urine flowing from an opening in the right vaginal wall. Cytoscopy demonstrated that the ureters did not terminate at the bladder. The endoscope passed easily from the vagina directly into a dilated right ureter. An excretory urogram confirmed the vaginal termination of at least one ureter, based upon extensive filling of the vagina with contrast media in the absence of bladder filling. Bilateral hydroureter and dilated renal pelves were demonstrated both by excretory urography and by urtrasonography. Euthanasia was required by the owner in lieu of attempted surgical correction. At necroscopy, it was confirmed that the right ureter entered the vagina and the left ureter terminated at the urethra. The diagnosis of bilateral ectopic ureter in this foal was suggested by this history and clinical signs, supported by endoscopy and ultrasonography, and confirmed by excretory urography and necropsy. This case establishes the value of diagnostic imaging techniques in the antemortem diagnosis of ectopic ureter

426

Acid production by vaginal flora in vitro is consistent with the rate and extent of vaginal acidification.  

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Perinatally, and between menarche and menopause, increased levels of estrogen cause large amounts of glycogen to be deposited in the vaginal epithelium. During these times, the anaerobic metabolism of the glycogen, by the epithelial cells themselves and/or by vaginal flora, causes the vagina to become acidic (pH approximately 4). This study was designed to test whether the characteristics of acid production by vaginal flora in vitro can account for vaginal acidity. Eight vaginal Lactobacillus isolates from four species-L. gasseri, L. vaginalis, L. crispatus, and L. jensenii-acidified their growth medium to an asymptotic pH (3.2 to 4.8) that matches the range seen in the Lactobacillus-dominated human vagina (pH 3.6 to 4.5 in most women) (B. Andersch, L. Forssman, K. Lincoln, and P. Torstensson, Gynecol. Obstet. Investig. 21:19-25, 1986; L. Cohen, Br. J. Vener. Dis. 45:241-246, 1969; J. Paavonen, Scand. J. Infect. Dis. Suppl. 40:31-35, 1983; C. Tevi-Bénissan, L. Bélec, M. Lévy, V. Schneider-Fauveau, A. Si Mohamed, M.-C. Hallouin, M. Matta, and G. Grésenguet, Clin. Diagn. Lab. Immunol. 4:367-374, 1997). During exponential growth, all of these Lactobacillus species acidified their growth medium at rates on the order of 10(6) protons/bacterium/s. Such rates, combined with an estimate of the total number of lactobacilli in the vagina, suggest that vaginal lactobacilli could reacidify the vagina at the rate observed postcoitally following neutralization by the male ejaculate (W. H. Masters and V. E. Johnson, Human sexual response, p. 93, 1966). During bacterial vaginosis (BV), there is a loss of vaginal acidity, and the vaginal pH rises to >4.5. This correlates with a loss of lactobacilli and an overgrowth of diverse bacteria. Three BV-associated bacteria, Gardnerella vaginalis, Prevotella bivia, and Peptostreptococcus anaerobius, acidified their growth medium to an asymptotic pH (4.7 to 6.0) consistent with the characteristic elevated vaginal pH associated with BV. Together, these observations are consistent with vaginal flora, rather than epithelial cells, playing a primary role in creating the acidity of the vagina. PMID:10496892

Boskey, E R; Telsch, K M; Whaley, K J; Moench, T R; Cone, R A

1999-10-01

427

Características anatómicas y fisiológicas de los músculos pélvicos en la coneja doméstica (Oryctolagus cuniculus) / Anatomical and physiological characteristics of pelvic muscles in the female rabbit (Oryctolagus cuniculus)  

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Full Text Available SciELO Mexico | Language: Spanish Abstract in spanish En mamíferos, la musculatura estriada pélvica se ha relacionado con la regulación de funciones urinarias y poco se sabe de su participación en funciones reproductivas. Los objetivos del presente estudio fueron determinar las características anatómicas y la inervación de los músculos iliococcígeo y p [...] ubococcígeo de la coneja adulta, y caracterizar la actividad electromiográfica (EMG) refleja en respuesta a la estimulación genital. Para ello se utilizaron técnicas quirúrgicas y electrofisiológicas. Los resultados muestran que el iliococcígeo y pubococcígeo son músculos bilaterales que se originan en el hueso iliaco; están inervados por ramas que emergen de S3 y S4; sus fibras musculares no se adhieren a las vísceras pélvicas, sino que discurren lateral a la vagina y al recto y se insertan en las vértebras sacras. Durante la estimulación de la piel del orificio vaginal y la vagina pélvica y perineal se presentó actividad EMG refleja en ambos músculos. La estimulación de la vagina abdominal no indujo respuesta EMG. La estimulación cervical produjo inhibición temporal en la actividad del iliococcígeo y pubococcígeo. Estos resultados contribuyen a las escasas descripciones anatómicas de la musculatura pélvica de la coneja que se encuentran en libros de texto y atlas; también sugieren que los músculos pélvicos iliococcígeo y pubococcígeo podrían activarse reflejamente durante procesos reproductivos, como la cópula y el parto. Abstract in english In mammals, the pelvic striated muscles have been linked to the regulation of urinary functions and little is known about the involvement of this muscle in reproductive functions. The objective of this study was to use surgical and electrophysiological techniques to determine the anatomical features [...] and innervation of iliococcygeus and pubococcygeus muscles in adult female rabbits and characterize the reflex electromyographic (EMG) activity in response to genital stimulation. Results show that the iliococcygeus and pubococcygeus are long bilateral muscles with fibers attached to the ilium bone. The muscle fibers are not attached to the pelvic viscera but they run adjacent to the vagina and rectum to be inserted into the sacral vertebrae. The iliococcygeus and pubococcygeus muscles are innervated by branches arising from S3 and S4. The reflex EMG activity was obtained during stimulation of the vaginal orifice skin and the perineal and pelvic vagina. Abdominal vaginal stimulation did not cause an EMG response. Cervical stimulation produced a temporary inhibition in the activity of the iliococcygeus and pubococcygeus. These findings extend the poor descriptions of innervation and anatomy of the striated pelvic musculature shown in the textbooks and atlas of rabbits. They also suggest that the iliococcygeus and pubococcygeous muscles can be activated by reflex action during reproductive processes such as mating and parturition.

Yolanda, Cruz; Dora Luz, Corona-Quintanilla; Margarita, Juárez; Margarita, Martínez-Gómez.

2010-12-01

428

Ultrastructure of the reproductive system of the black swamp snake (Seminatrix pygaea). II. Annual oviducal cycle.  

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This article is the first ultrastructural study on the annual oviducal cycle in a snake. The ultrastructure of the oviduct was studied in 21 females of the viviparous natricine snake Seminatrix pygaea. Specimens were collected and sacrificed in March, May, June, July, and October from one locale in South Carolina during 1998-1999. The sample included individuals: 1) in an inactive reproductive condition, 2) mated but prior to ovulation, and 3) from early and late periods of gravidity. The oviduct possesses four distinct regions from cranial to caudal: the anterior infundibulum, the posterior infundibulum containing sperm storage tubules (SSTs), the uterus, and the vagina. The epithelium is simple throughout the oviduct and invaginations of the lining form tubular glands in all regions except the anterior infundibulum and the posterior vagina. The tubular glands are not alveolar, as reported in some other snakes, and simply represent a continuation of the oviducal lining with no additional specializations. The anterior infundibulum and vagina show the least amount of variation in relation to season or reproductive condition. In these regions, the epithelium is irregular, varying from squamous to columnar, and cells with elongate cilia alternate with secretory cells. The secretory product of the infundibulum consists largely of lipids, whereas a glycoprotein predominates in the vagina; however, both products are found in these regions and elsewhere in the oviduct. In the SST area and the anterior vagina, tubular glands are compound as well as simple. The epithelium of the SST is most active after mating, and glycoprotein vacuoles and lipid droplets are equally abundant. When present, sperm form tangled masses in the oviducal lumen and glands of the SST area. The glands of the uterus are always simple. During sperm migration, a carrier matrix composed of sloughed epithelial cells, a glycoprotein colloid, lipids, and membranous structures surround sperm in the posterior uterus. During gravidity, tubular glands, cilia, and secretory products diminish with increasing development of the fetus, and numerous capillaries abut the basal lamina of the attenuated epithelial lining of the uterus. PMID:10906748

Sever, D M; Ryan, T J; Morris, T; Patton, D; Swafford, S

2000-08-01

429

[Our experience in the Martius method of closing the vesicovaginal fistula].  

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Sometimes after delivery, gynecological or other surgeries, radiological therapy, or destructions of vesico-vaginal septum due to the tumor or trauma, the unnatural communication between the bladder and vagina occurs. Those are fistulas that occur after the delivery (tocogenic) caused by the prolonged delivery or some obstetrics operations. Some fistulas are high, coming from the fundus of the bladder, medium, if they come just behind the trigonum of the bladder, and low, if they are in the level of trigonum and the neck of the bladder. The purpose of this paper is to show the operative technique of elimination of medium and low vesicovaginal fistula and the results of the treatment. Material and method The elimination of the vesicovaginal fistula by original Martius technique is done through vagina. The catheter is inserted through the fistula (figure 1). Than the mucosis of the vagina is cut around the fistula and the vaginal wall is separated from the bladder. The catheter is pulled out and the fistula on the bladder is sown with resorptive stitches. Than the labia maiora nearer to the fistula is cut along from Mons Veneris to the middle and the lipoid tissue is taken with vascular pedicle (figure 2). This tissue is put between the bladder and the vagina and fixed with resorptive stitches. After that the vagina is sown by single stitches. The labia maiora that was cut is also sown by single stitches (figure 3). Than the catheter is inserted in the bladder that should stay there for four weeks. This is the method we used to make surgery in twenty patients with vesicovaginal fistula. The first one had the fistula as the result of the Caesarean section. She was operated twice through the bladder without success. The second patient was a fourteen years old girl that cut herself on the glass and damaged anal sfincter, rectum, vagina and the bladder. The fistula appeared later in the level of trigonum of the bladder. The other eighteen patients got fistula after hysterectomy. All patients were treated as described above and fistulas disappeared. The first patient had another baby a year after the operation by Caesarean section. The other patients have regular miction (figure 4 and 5). Discussion and the conclusion Vesicovaginal fistula are serous complications, for the patients and for the doctors. The only treatment of the vesicovaginal fistula is surgical. If any damage of the bladder occurs during any operation it should be treated immediately, otherwise the fistula will appear. The treatment depends of the localization of the fistula. Low fistulas and some medium and urethrovaginal fistulas should be approached through vagina and according to our experience Martius's method is very efficient. The only important thing is when the fistula is detected to wait at least for two or three months for the fistula to "consolidate" and also to cure the infection. PMID:16018375

Djordjevi?, M; Stanojevi?, D; Perovi?, S

2004-01-01

430

Prevención del prolapso genital en histerectomía abdominal utilizando los ligamentos redondos: Experiencia personal  

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Full Text Available SciELO Venezuela | Language: Spanish Abstract in spanish Objetivo: Prevenir el prolapso de la cúpula vaginal, empleando una técnica peroperatoria que consiste en fijar la cúpula vaginal a los ligamentos redondos, en el momento de realizar la intervención. Métodos: Realizada la histerectomía, se procedió al cierre de la cúpula vaginal con puntos separados [...] en número de 6 a 8 con material no absorbible, dependiendo de la amplitud de la vagina. Los cabos distales son utilizados para anudar horizontalmente los ligamentos redondos. La fijación de las dos paredes del extremo superior de la vagina, garantiza mayor estabilidad de la vagina y menor posibilidad de producir el prolapso de la cúpula y/o de las paredes anterior y posterior de la vagina. Ambiente: Servicio de Ginecología, Hospital Universitario de Caracas Resultados: Las 124 pacientes histerectomizadas y controladas anualmente en un lapso entre 2 y 27 años, con un promedio de 7 años, ninguna de ellas presentó prolapso de cúpula vaginal. Las histerectomías se realizaron en el ejercicio privado. En centros asistenciales públicos, es muy difícil hacer seguimiento y evaluar las pacientes, por razones múltiples. Conclusiones: La histerectomía ocupa el primer lugar de las intervenciones ginecológicas, esto obliga a realizar la suspensión y fijación de la cúpula vaginal y simultáneamente corregir la patología asociada del aparato genital. El procedimiento que hemos empleado tuvo resultados muy favorables. La calidad de vida de las mujeres intervenidas quirúrgicamente no se desmejoró, como suele suceder cuando se produce el prolapso de la cúpula vaginal. Abstract in english Objective: To prevent vaginal vault prolapse, using a preoperative technique to fix the vaginal vault to the round ligaments in total abdominal hysterectomy, and identify associated pathology in the genital area. Methods: After hysterectomy, we proceed to the closure of the vaginal vault with interr [...] upted sutures with non-absorbable material, in number of 6-8, depending of the amplitude of the vagina, the distal ends are used to tie horizontally bilateral round ligaments. The setting of the two upper walls of the vagina, ensures greater stability of the vagina and lower possibility of occurrence of prolapse of the dome and/or the anterior and posterior vaginal walls. Setting: Servicio de Ginecologia, Hospital Universitario de Caracas Results: The 124 patients undergoing hysterectomy, checked annually over a period of time between 2 and 27 years, with an average of 7 years, neither had vaginal prolapse. Conclusion: Histerectomy is the firstone gynecological operation. It requires making the suspension and fixation of the vaginal vault and simultaneously correct the genital tract associated pathology. The procedure we used had very favorable results. We can not compare our results with other techniques, do to scarse national an international references. The quality of life of women surgically intervened did not deteriorated, as usually happens when there is prolapse of the vaginal vault.

Farith, Atías.

431

Patología vaginal: utilidad de la citología y la colposcopia como métodos diagnósticos  

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Full Text Available SciELO Venezuela | Language: Spanish Abstract in spanish Objetivo: Evaluar la citología y la colposcopia como métodos diagnósticos de patología vaginal. Métodos: Estudio prospectivo y descriptivo que incluyó 100 pacientes. Se realizó citología, colposcopia y biopsia dirigida o del tercio superior de vagina, cuando no había lesiones. Resultados: La edad me [...] dia de las pacientes fue 37,7 años. Hubo patología vaginal en 81 pacientes: 19 (23,4.%) neoplasias intraepiteliales vaginales I y 62 (76,5 %) lesiones no neoplásicas, entre ellas 47 (75,8.%) con infección por virus de papiloma humano y 15 (24,2 %) con otras lesiones. Entre las 37 pacientes con cambios colposcópicos, 56,8 % tenían epitelio acetoblanco fino, 45,9 % de los cambios estaban en el tercio superior. Hubo 5 casos de lesiones multifocales. Dos citologías presentaron cambios por virus de papiloma humano. En 66 pacientes hubo cambios histológicos compatibles con infección por este virus, 19 con neoplasia. La sensibilidad y especificidad de la citología para lesiones neoplásicas intraepiteliales fue 0 % y 100 %, de la colposcopia 47 % y 78 % y de ambos 75 % y 16 %, respectivamente. Los factores de riesgo significativos para infección por virus de papiloma humano y neoplasia intraepitelial fueron: edad, patología cervical y vulvar previa, uso de anticonceptivos orales y tabaquismo. Existe asociación significativa entre patología cervical o vulvar y el diagnóstico de infección por virus de papiloma humano en vagina. Conclusiones: La citología no debe ser usada aisladamente como método de pesquisa de lesiones neoplásicas de la vagina; se recomienda asociarla a la colposcopia vaginal. Abstract in english Objective: To evaluate the colposcopy and cytology as vaginal pathology diagnostic methods. Methods: prospective and descriptive study involving 100 patients. Cytology, colposcopy and directed biopsy, or in the upper vagina third when there was no injuries, was conducted. Results: The average age of [...] the patients was 37.7 years. There was vaginal pathology in 81 patients: 19 (23.4 %) vaginal intraepithelial neoplasia I and 62 (76.5 %) injuries non neoplastic, including 47 (75.8.%) with infection by human papillomavirus and 15 (24.2 %) with other injuries. Among the 37 patients with colposcopy changes, 56.8 % had fine acetoblanco epithelium, 45.9 % of the changes were in the upper third. There were 5 cases of multifocal lesions. Two PAP submitted changes for human papillomavirus. In 66 patients there were histological changes consistent with infection by this virus, 19 with neoplasia. The sensitivity and specificity of cytology for intraepithelial neoplastic lesions was 0 % and 100 %, for the colposcopy 47 per cent and 78 per cent, and for both methods, 75 % and 16 %, respectively. Significant risk factors for infection of human papillomavirus and intraepithelial neoplasia were: age, prior cervical and vulvar disease, use of oral contraceptives and smoking. There is significant association between cervical or vulvar pathology and the diagnosis of infection of human papillomavirus in vagina. Conclusions: Cytology should not be used alone as a method of investigation of neoplastic lesions of the vagina; It is recommended to associate it with the vaginal colposcopy.

Yanyn Betzabe, Uzcátegui; María Carolina, Tovar; Coromoto Jacqueline, Lorenzo; Mireya, González.

432

Evaluación de la toxicidad vaginal de Croton lechleri en conejas / Assessment of Croton lechleri vaginal toxicity in rabbits  

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Full Text Available SciELO Peru | Language: Spanish Abstract in spanish Objetivo: Evaluar la toxicidad vaginal de una preparación en gel de Croton lechleri en conejas. Diseño: Estudio experimental. Institución: Centro de Investigación de Bioquímica y Nutrición Alberto Guzmán Barrón, Instituto de Investigaciones Clínicas, Instituto de Patología de la Facultad de Medicina [...] , y Facultad de Farmacia, Universidad Nacional Mayor de San Marcos, Lima, Perú. Material biológico: Resina de Croton lechleri y conejos hembras, blancos, Nueva Zelanda. Métodos: Los animales fueron distribuidos en tres grupos (n=5): I. Control, vehículo; II, C. lechleri 1%; y III, C. lechleri 5%; los conejos recibieron estas muestras en un volumen de 1 mL por vía intravaginal, una vez/día, durante 10 días consecutivos. Se observó el estado clínico general, así como la apariencia física de la vagina y el perineo por signos de flujo, eritema y edema. Al final del experimento se realizó la exéresis quirúrgica de la vagina de cada coneja y se evaluó macroscópicamente, buscando signos de irritación, sangrado o daño de la mucosa. Luego, se fijó en formol tamponado al 10% y posteriormente se tomó tres muestras representativas de las regiones cérvico-vaginal, media-vaginal, y urovaginal, para el estudio histopatológico. Principales medidas de resultados: Irritación vaginal. Resultados: El examen macroscópico de la vagina en el grupo control mostró aspecto congestivo leve en forma difusa, en todos los casos, y de aspecto similar en las muestras del grupo Croton lechleri al 1%. En la formulación al 5%, en dos casos se observó congestión petequial parcial leve. El estudio histopatológico reveló un puntaje promedio de irritación vaginal de 3,4 a 6 y 3,6 a 8 para las preparaciones al 1% y 5%, respectivamente. Conclusión: En nuestras condiciones experimentales, las preparaciones de gel de C. lechleri evaluadas fueron no irritantes para la mucosa vaginal y resultaron aceptables. Abstract in english Objective: To determine a Croton lechleri vaginal gel preparation toxicity in rabbits. Design: Experimental study. Setting: Alberto Guzman Barron Biochemistry and Nutrition Research Center, Clinical Research Institute, Institute of Pathology, Faculty of Medicine and Pharmacy Faculty, Universidad Nac [...] ional Mayor de San Marcos, Lima, Peru. Biological material: Croton lechleri resin and female white New Zealand rabbits. Methods: The animals were divided into three groups (n=5): I. Control, vehicle; II, C. lechleri 1%, and III, C. lechleri 5%; they received samples of 1 mL volume intravaginally 1 time/day for 10 consecutive days. The general clinical condition and physical appearance of the vagina and the perineum for signs of flow, erythema and edema were observed. At the end of the experiment surgical resection of the vagina of each rabbit was performed and signs of irritation, bleeding or mucosal damage were determined macroscopically. Specimens were placed in 10% buffered formalin and cervico-vaginal, mid-vaginal, and uro-vaginal samples underwent histopathology study. Main outcome measures: Vaginal irritation. Results: Gross examination of the vagina in both the control and the Croton lechleri 1% groups showed mild diffuse congestion. Two cases of Croton lechleri 5% formulation showed mild petechial congestion. Histopathology study revealed a vaginal irritation average score of respectively 3.4 to 6, and 3.6 to 8 for the 1% and 5% preparations. Conclusions: In our experimental conditions, gel preparations of C. lechleri evaluated were acceptable and not irritating to the vaginal mucosa.

Salomón, Ayala; Juan, Rojas; David, Díaz; José, Juárez; Carlos, Delgado.

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MORPHOLOGICAL AND HISTOCHEMICAL ASPECTS OF THE LUMINAL OVIDUCTAL EPITHELIUM OF THE LAYING AND NONLAYING MUSCOVY DUCK (Cairina moschata, LINNEAUS, 1758 ASPECTOS MORFOLOGICOS E HISTOQUIMICOS DEL EPITELIO LUMINAL DEL OVIDUCTO DE LA PATA SILVESTRE (Cairina moschata, LINNAEUS, 1785 DURANTE LOS PERIODOS DE POSTURA Y NO POSTURA  

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Full Text Available The authors have used three laying and three non-laying muscovy ducks (Cairina moschata, Linneaus, 1758, in order to study morphological and histochemical aspects of the luminal oviductal epithelium. The results showed that the oviduct of the muscovy duck is well-developed at the left side, atrophied at the right side and consists of six different regions: fimbria, infundibulum, magnum, isthmus, shell-gland and vagina. The oviduct is more evident and developed in the laying phase of the reproductive period. The lining epithelium is of single cylindric ciliated type, with the exception of the region of the vagina, where it is of pseudo-stratified cylindric ciliated type. In all portions of the oviduct it was observed that the epithelium presents ciliated and non-ciliated cells. It was verified a predominance of non-ciliated cells in the laying period and of ciliated cells in the nonlaying period, with the exception of the regions of the fimbriae and shell-gland, where an equilibrium of these two cell-types is observed. With regard to the detection of mucous substances, it was noted that the surface ovid