uma cepa knockout: Topics by WorldWideScience.org

A critical assessment of the radiation doses at a pediatric hospital; Uma avaliacao critica das doses de radiacao em um hospital pediatrico

No abstract prepared.

2008-07-01

Heavy metals in industrial wastewater determined by radionuclide x-ray fluorescence analysis and their effects on Allium cepa root tip cells

No abstract prepared.

2006-07-01

Impact of the regulation on information about new substances derived from the Canadian Environmental Protection Act (CEPA) on the application of biotechnological treatment of AMD : a case study; Impact du reglement sur les renseignements concernant les substances nouvelles de la LCPE sur l'application d'une biotechnologie de traitement du DMA : etude de cas

Radionuclide x-ray fluorescence method was used in the determination of Cr, Ni and other heavy metals content in wastewater of an engineering plant taken both before and after chemical treatment. Toxic effects of the wastewaters using Allium cepa root tip cells were tested. (author) 8 refs.; 2 tabs.

1994-05-01

Dispersive potential and spontaneous decay rate of an atom near a conducting wedge; Potencial dispersivo e taxa de decaimento espontaneo de um atomo proximo a uma cunha condutora

This poster presentation covered a number of issues related to the new regulations concerning information on new substances derived from the Canadian Environmental Protection Act (CEPA). The authors described the background, and the objectives of the research project. A brief overview of the Acid Mine Drainage (AMD) process was provided, as well as the sulphate reduction process. The general methodology was explained, and the results of the bioactivation presented. The process followed for the bioaugmentation and the results obtained were presented. The regulations concerning information on new substances derived from the CEPA were described. The authors then presented their conclusions and perspectives. 26 figs.

2000-07-01

An iso spectral potential class with a 1D relativistic q-oscillator; Uma classe de potenciais isoespectrais com o q-oscilador relativistico 1D

No abstract prepared.

2007-07-01

The vacuolar processing enzyme (VPE) mutation suppresses an HR-like cell death induced by the double knockout mutant of vacuolar Ca2+-ATPases in Arabidopsis

Short communication.

1996-12-31

KoreaScience (Korea)

Full Text Available

2011-06-01

Hormone-Sensitive Lipase Knockouts

Polyphenols in the active fraction of needle-prick (Dasyphyllum brasiliense, Asteraceae), a medicinal plant with antiinflammatory activity; Polifenois na fracao ativa de espinho-agulha (Dasyphyllum brasiliense, Asteraceae), uma planta medicinal com atividade antiinflamatoria

All treatments for obesity, including dietary restriction of carbohydrates, have a goal of reducing the storage of fat in adipocytes. The chief enzyme responsible for the mobilization of FFA from adipose...Full Text Available

Measurement of a continuous curve for alpha particles stopping power in aluminium at the Bragg peak region; Medida de uma curva continua do poder de freamento de particulas alfa em Al na regiao do pico de Bragg

No abstract prepared.

2008-07-01

Feynman graphs and generalized eikonal approach to high energy knock-out processes

No abstract prepared.

2008-07-01

Decreased dendritic spine density and abnormal spine morphology in Fyn knockout mice

The cross section of hard semiexclusive A(e,e"'N)(A-1) reactions for fixed missing energy and momentum is calculated within the eikonal approximation. Relativistic dynamics and kinematics of high energy processes are unambiguously accounted for by using the analysis of appropriate Feynman diagrams. A significant dependence of the final state interactions on the missing energy is found, which is important for interpretation of forthcoming color transparency experiments. A new, more stringent kinematic restriction on the region where the contribution of short-range nucleon correlations is enhanced in semiexclusive knock-out processes is derived. It is also demonstrated that the use of light-cone variables leads to a considerable simplification of the description of high energy knock-out reactions. copyright 1997 The American Physical Society.

British Library Electronic Table of Contents (United Kingdom)

Fyn is a Src-family tyrosine kinase that affects long term potentiation (LTP), synapse formation, and learning and memory. Fyn is also implicated in dendritic spine formation both in vitro and in vivo. However, whether Fyn's regulation of dendritic spine formation is brain-region specific and age-dependent is unknown. In the present study, we systematically examined whether Fyn altered dendritic spine density and morphology in the cortex and hippocampus and if these effects were age-dependent. We found that Fyn knockout mice trended toward a decrease in dendritic spine density in cortical layers II/III, but not in the hippocampus, at 1month of age. Additionally, Fyn knockout mice had significantly decreased dendritic spine density in both the cortex and hippocampus at 3months and 1year, an...

2011-01-01

Targeted Deletion of Somatotroph Insulin-Like Growth Factor-I Signaling in a Cell-Specific Knockout Mouse Model

Modeling RNA polymerase competition: the effect of ?-subunit knockout and heat shock on gene transcription level

The role of IGF-I in the negative regulation of GH expression and release is demonstrated by in vitro and in vivo models; however, the targets and mechanisms of IGF-I...Full Text Available

2010-05-01

Knockout of Arabidopsis ACCELERATED-CELL-DEATH11 encoding a sphingosine transfer protein causes activation of programmed cell death and defense

BackgroundModeling of a complex biological process can explain the results of experimental studies and help predict its characteristics. Among such processes is transcription in...Full Text Available

Functional and Behavioral Restoration of Vision by Gene Therapy in the Guanylate Cyclase-1 (GC1) Knockout Mouse

We describe the lethal, recessive accelerated-cell-death11 Arabidopsis mutant (acd11). Cell death in acd11 exhibits characteristics of animal apoptosis...Full Text Available

2002-02-15

NEW DEVELOPMENT IN THE VACUUM MELTING AND CASTING OF URANIUM IN TONNAGE QUANTITIES. Transactions of the Vacuum Metallurgy Conference, 1960

BackgroundRecessive mutations in guanylate cyclase-1 (Gucy2d) are associated with severe, early onset Leber congenital amaurosis-1(LCA1). Gucy2d...Full Text Available

Science.gov (United States)

> Develoopments which have imporved fuel core quality and reduced production costs are described. These developments in the melting and casting of uranium ingots arei modification of the crucible and knockout-slide assembly, substitution of uncoated crucibles for coated crucibles, and substitution of a one-piece gun barrel mold for a vertically split mold. (N.W.R.)

1961-01-01

Deficiency in trefoil factor 1 (TFF1) increases tumorigenicity of human breast cancer cells and mammary tumor development in TFF1-knockout mice

Although trefoil factor 1 (TFF1; previously named pS2) is abnormally expressed in about 50% of human breast tumors, its physiopathological role in this disease has been poorly studied. Moreover,...Full Text Available

2011-07-21

?_1A/B-Knockout mice explain the native ?_1D-adrenoceptor's role in vasoconstriction and show that its location is independent of the other ?₁-subtypes

PurposePrevious studies have demonstrated that in 129α3Cx46^−/− mice, age-related nuclear cataract is formed. In...Full Text Available

2007-06-01

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Electric induction on a trolley bus contact line, running parallel to a 138 KV overhead transmission line; Inducao em linha de contato de trolebus paralela a uma linha de transmissao de 138 kV

Background and purpose:Theoretically, three α₁-adrenoceptor subtypes can interact at the signalling level to alter vascular contraction or at the molecular level...Full Text Available

2009-12-01

Development of a synchronous key to controlled energization of three-phase transformers; Desenvolvimento de uma chave sincrona para energizacao controlada de transformadores trifasicos

Results obtained on induced current and voltage caused by a high voltage transmission lines running parallel at a trolley bus contact lines, are presented. A computer program in Basic language, was developed to calculate the electric induction, problems of safety, a theoretical development and mathematical model of the electric factors between two lines (inductor and induced) are also discussed. 11 figs., 1 tab., 8 refs.

1991-12-31

Determination of the semi-empiric relationship among the physical density, the concentration and rate between hydrogen and manganese atoms, and a manganese sulfate solution; Determinacao da relacao semi-empirica entre a densidade fisica, concentracao e razao entre atomos de hidrogenio e manganes em uma solucao de sulfato de manganes

This work describes the development of a synchronous key based on micro controller to the switching of three-phase power transformers, which makes possible the achievement of tests to register the inrush current, and the previous establishment of the instantaneous values of the voltage firstly applied to different phases of the energy process. This key is a value tool to the development electric power system projects and to the teaching and researching activities at the laboratory related to transitory phenomena and electric system protection.

2009-07-01

Distribution of 6 q functions in nuclei and quark enhancement of hard processes with deuteron emission

The bath of a manganese sulfate (BMS) is a system for absolute standardization of the neutron sources. This work establishes a functional relationship based on semi-empirical methods for the theoretical prediction of physical density values, concentration and rate between the hydrogen and manganese atoms presents in the solution of the BMS

2009-07-01

Clustering information from direct nuclear reactions

"2H, "4He, "1"6O, "4"0Ca, "8"0Zr, "1"4"0Yb, "2"2"4112, "3"3"6168 nuclei are invesigated in terms of flucton model. Effective numbers of nuclear fluctons and deuterons are calculated. Values of complete effective numbers of low-radius deuterons and fluctons with S=1 spin and T=0 isospin are presented. Investigation results of inclusive reactions of quasi-elastic knock-out of deuterons by fast protons are discussed. 9 refs.; 1 fig.; 1 tab.

1988-06-14

Phloem loading: an integrated approach

Direct nuclear reactions are commonly understood in terms of distorted wave (DW) formalisms. In the case of a single nucleon knockout or transfer reaction the DW analysis provides a reasonable understanding of the observed data. On the other hand the predictions based on different available information inputs have been verified with the observations consistently. In the case of direct reactions involving nuclear clusters however, the DW predictions have been found to disagree with the observations in most cases. The outcome of these and other improvements in the intermediate energy nuclear phenomena involving direct reactions are highlighted. (author). 13 refs., 18 figs.

Biological and chemical evaluation of sewage water pollution in the Rietvlei nature reserve wetland area, South Africa

This study focuses on the regulation of sucrose transport across the plasmalemma. Initially, we re-examined the use of leaf discs to study the kinetics of phloem loading using Allium cepa leaves. All tissues exhibited the same linear plus saturable profile as Beta vulgaris, except fructose uptake into the inner parenchyma and bundle-sheath cells; in this case the response was linear. These results indicate that all tissues of the leaf retrieve exogenous sucrose such that kinetics from leaf discs cannot be taken to represent phloem loading per se. We continued our study by investigating the influence of internal sugars on sugar transport across the plasmalemma. We found that if internal sugars were manipulated by heat-girdling techniques or DCMU treatment there was no appreciable change in sucrose influx. However, longer term heat-girdling decreased sucrose uptake. These data indicate that carbohydrate partitioning among the chloroplast, cytosol, and vacuole ...

1986-01-01

A contribution to the study of the thermal behavior and of the electric performance of squirrel-cage induction motors; Uma contribuicao ao estudo do comportamento termico e do desempenho eletrico de motores de inducao com rotor em gaiola

Macroinvertebrate communities in Rietvlei nature reserve wetland area and their relationship with water quality were studied with the aim to evaluate their use as potential indicators of pollution. Sampling locations were selected to include outlets from swage effluent, agricultural and informal residential runoff. A large increase in nutrient concentrations was observed downstream from discharged treated sewage with an associated decrease in species richness. Bioassays performed included: Daphnia magna, Hydra attenuate, Lactuca sativa, Allium cepa and Pyxicephalus adspersus. The highest percentage of lethality response to a screen (100% concentration) of sampled wetland water by test specimens were observed at the point source input of the Hartbeespoort treated sewage plant. Data generated from the AUSRIVAS method and multitrophic level bioassays revealed the deterioration of the wetland possibly due to factors such as increasing urbanization, industrialization, ...

2008-11-01

Role of Fgf receptor 2c in adipocyte hypertrophy in mesenteric white adipose tissue

A thermal-electric mathematical model for a squirrel cage induction motors which permits to specify the best motor for specific drive, under thermal and electric aspects based, only on manufacturer technical bulletins and technical information is presented. Changes of rotor parameters due Skin Effect and changes of winding resistances (both stator and rotor) with the temperature are considered. The accuracy of this model is appraised using experimental results. The thermal behavior and electric performance for some motors are obtained for continuos and intermittent duties with sinusoidal and non-sinusoidal voltages. (author)

1992-03-01

British Library Electronic Table of Contents (United Kingdom)

Fgf receptor 2c (Fgfr2c) was expressed in mature adipocytes of mouse white adipose tissue (WAT). To examine the role of Fgfr2c in mature adipocytes, we generated adipocyte-specific Fgfr2 knockout (Fgfr2 CKO) mice. The hypertrophy impairment of adipocytes in the mesenteric WAT but not in the subcutaneous WAT and decreased plasma free fatty acid (FFA) levels were observed in Fgfr2 CKO mice. Although the expression of genes involved in adipocyte differentiation and lipid metabolism in the mesenteric WAT was essentially unchanged, the expression of uncoupling protein 2 potentially involved in energy dissipation was significantly increased. Among potential Fgf ligands for Fgfr2c, Fgf9 was preferentially expressed in the mesenteric WAT. The present findings indicate that Fgfr2c potentially activ...

2008-01-01

Nuclear structure of light Ca and heavy Cr isotopes

Growth factor signalling in the regulation of -cell fate

In the present thesis, the shell structure in exotic nuclei has been investigated. The focus of the work was on finding new experimental data in neutron-rich Cr and proton-rich Ca isotopes. The investigation of light Ca isotopes concentrated on the nucleus {sup 36}Ca which was produced in a knockout reaction from a radioactive {sup 37}Ca beam. For {sup 36}Ca, the excitation energy of the first 2{sup +} state has been measured for the first time. Furthermore, momentum distributions were analyzed using a Monte-Carlo simulation of the knockout reaction. This analysis yielded the contributions of neutrons from individual orbitals to the total knockout cross section. In principle, these may be used to calculate spectroscopic factors, but such a calculation is hampered by difficulties of present knockout-reaction models in predicting precise single-particle cross sections. The measured branching ratio to the ...

2007-07-01

British Library Electronic Table of Contents (United Kingdom)

Glucagon plays critical roles in regulating glucose homeostasis, mainly by counteracting the effects of insulin. Consequently, the dysregulated glucagon secretion that is evident in type 2 diabetes has significant implications in the pathophysiology of the disease. Glucagon secretion from pancreatic -cells has been suggested to be modulated by blood glucose, signals from the nervous system and endocrine components. In addition to these regulators, intraislet factors acting in a paracrine manner from neighbouring -cells are emerging as central modulator(s) of -cell biology. One of the most important of these paracrine factors, insulin, modulates glucagon secretion. Indeed, the -cell-specific insulin receptor knockout (IRKO) mouse manifests hypersecretion of glucagon in the postprandial stag...

2011-01-01

Detection of behavioral alterations and learning deficits in mice lacking synaptophysin

British Library Electronic Table of Contents (United Kingdom)

The integral membrane protein synaptophysin is one of the most abundant polypeptide components of synaptic vesicles. It is not essential for neurotransmission despite its abundance but is believed to modulate the efficiency of the synaptic vesicle cycle. Detailed behavioral analyses were therefore performed on synaptophysin knockout mice to test whether synaptophysin affects higher brain functions. We find that these animals are more exploratory than their wild type counterparts examining novel objects more closely and intensely in an enriched open field arena. We also detect impairments in learning and memory, most notably reduced object novelty recognition and reduced spatial learning. These deficits are unlikely caused by impaired vision, since all electroretinographic parameters measur...

2009-01-01

Conjugation is essential for the anticholestatic effect of NorUrsodeoxycholic acid in taurolithocholic acid induced cholestasis in rat liver

British Library Electronic Table of Contents (United Kingdom)

Abstract NorUDCA (24 norursodeoxycholic acid), the C23 homolog of ursodeoxycholic acid (UDCA), showed remarkable therapeutic effects in cholestatic Mdr2 (Abcb4) (multidrug resistance protein 2/ATP binding cassette b4) knockout mice with sclerosing/fibrosing cholangitis. In contrast to UDCA, norUDCA is inefficiently conjugated in human and rodent liver, and conjugation has been discussed as a key step for the anticholestatic action of UDCA in cholestasis. We compared the choleretic, anticholestatic, and antiapoptotic properties of unconjugated and taurine conjugated UDCA (C24) and norUDCA (C23) in isolated perfused rat liver (IPRL) and in natrium/taurocholate cotransporting polypeptide (Ntcp) transfected human hepatoma (HepG2) cells. Taurolithocholic acid (TLCA) was used to induce a predomi...

2010-01-01

Re-potentiation of hydro-generators: a proposal of analysis and implementation methodology; Repotenciacao de hidrogeradores: uma proposta de metodologia de analise e implantacao

Atmospheric emissions as a tool in evaluation of sustainability research in oil industry; Emissao atmosferica como uma ferramenta na avaliacao do desenvolvimento sustentavel na industria do petroleo

The hydro-generators suffer during its operative useful life a combination of stresses of nature thermal, electric, mechanics and environmental. With the time, they are going losing the capacity to support those stresses and the power plants suffer, more and more frequently, undesirable stops for repair services and maintenance. In function of the high costs incurred with these stopped, the operation of the power plant can be economically impracticable. That unavailability of the generation for the electric system, it results in reduction of the reliability, burdening the politics of load ruling. The re-potentiation is a proposal that seeks to extend the useful life of hydro-generators, at the same time that it try to rescue the reliability and the readiness of the plant, with larger power. The power increase is usually made possible, or for the surplus of the hydro resources in excess, or for the reduction of the losses of all the components of the energy flow. That work proposes a ...

1996-07-01

Reply to comments on the proposed on-road vehicle and engine emission regulations

This work is directly to analysis of atmosphere surrounding Ipiranga Refinery; witch is located in the city of Rio Grande, in estate of Rio Grande do Sul. The refinery is surrounded by neighborhood, witch are impacted by atmospheric emissions of refinery. The objective of this work is correlating the refinery to the inhabitants that lives near the refinery, using an environmental sustainability index. This work will be achieve by analysis of Polycyclic Aromatic Hydrocarbons (PAH) bounded in particulate matter with diameter of 100 {mu}m (PTS), the acquisition of health data on the city hospitals and correlation of this data with PAH concentrations in Particulate Matter. The Samples were obtain by FEPAM, witch have three samples sites in the center of city. The samples was obtained by a High Volume Sampler equipped with quartz fiber filters. The meteorological data important to this work, like wind direction and speed, will be obtain in Meteorological Station on FURG. The results expect ...

2008-07-01

Formation of nanostructures in UO_2 fuel at high burn-ups

In February 2001, the Minister of Environment Canada outlined a series of measures to be implemented over the next decades to reduce emissions from vehicles, engines and fuels. The agenda includes the development of new regulations under the authority of Part 7, Division 5 of the Canadian Environmental Protection Act (CEPA) to align Canada's emission standards for on-road vehicles with those of the United States Environmental Protection Agency. This paper presents a detailed summary of comments received by the interested parties that appeared at a public consultation in November 2001 to discuss and raise issues about the proposed regulations. The parties that provided submissions included: governments; the vehicle and engine manufacturing industry; the oil industry; other groups of associations such as the Canadian Trucking Alliance, David Suzuki Foundation, and West Coast Environmental Law; and, five private individuals. The report presents comments and ...

2002-12-01

Uranium hexafluoride production plant decommissioning; Descomissionamento de uma usina de producao de hexafluoreto de uranio

In the present paper it is assumed that above a limiting value of fission fluency (burn-up) a more intensive process of irradiation introduced chemical interaction occurs. A significant part of fission gas product is thus expected to be chemically bounded in the matrix of UO_2 fuel. The fission gas atoms substituting, for example, uranium atoms in the crystallographic lattice can form weak facets. At a certain saturation condition, division of the grains can occur at the weak facets and the increase in fission-gas products release may be expected. The fact that the process of grain division for high burn-ups (70-80 MWd/kgU) forms an extremely fine structure up to the temperature as high as 1100 "oC and simultaneously the observed decreases in fission gas concentration in the fuel supports this concept. The analysis of fission gas concentration change due to the formation of nanostructures in UO_2 fuel at high burn-ups in terms of total surface area change in a function of burn-up and ...

2001-09-23

Occupational exposure prevention program to oil and gas industry; Antecipacao, reconhecimento, avaliacao e controle dos riscos ambientais em uma planta de petroleo e gas

The Institute of Energetic and Nuclear Research - IPEN is a research and development institution, located in a densely populated area, in the city of Sao Paulo. The nuclear fuel cycle was developed from the Yellow Cake to the enrichment and reconversion at IPEN. After this phase, all the technology was transferred to private enterprises and to the Brazilian Navy (CTM/SP). Some plants of the fuel cycle were at semi-industrial level, with a production over 20 kg/h. As a research institute, IPEN accomplished its function of the fuel cycle, developing and transferring technology. With the necessity of space for the implementation of new projects, the uranium hexafluoride (UF{sub 6}) production plant was chosen, since it had been idle for many years and presented potential leaking risks, which could cause environmental aggression and serious accidents. This plant decommission required accurate planning, as this work had not been carried out in Brazil before, for this type of facility, and ...

2008-07-01

Markov random fields simulation: an introduction to the stochastic modelling of petroleum reservoirs; Simulacao de campos aleatorios markovianos: uma introducao voltada a modelagem estocastica de reservatorios de petroleo

PETROBRAS/TRANSPETRO Pipelines and Terminals have 500 regular employees and 5.064 out sourced workers in its Southeast Division. The out sourced employees work under 125 contracts involving a wide range of activities such as maintenance, pipeline operation, pipeline launching, engineering, administrative and auxiliary services. Among these workers, 1.200 peoples are subjected to occupational exposure, which may be present in the industrial process or in the products transported in our pipelines, e.g. industrial noise, sulfidric gas, toluene, xylene and benzene (recognized as a carcinogen according to ACGIH and Brazilian Ministry of Labour). Our PPRA (acronym in Portuguese for Occupational Exposure Prevention Program) involves the workforce and fosters health by anticipation, recognition, evaluation and control of the situations that may result in injuries. Further actions include the procurement of equipment for detection of these agents not only in the air but also diluted in liquids ...

2005-07-01

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Science.gov (United States)

Stochastic simulation has been employed in petroleum reservoir characterization as a modeling tool able to reconcile information from several different sources. It has the ability to preserve the variability of the modeled phenomena and permits transference of geological knowledge to numerical models of flux, whose predictions on reservoir constitute the main basis for reservoir management decisions. Several stochastic models have been used and/or suggested, depending on the nature of the phenomena to be described. Markov Random Fields (MRFs) appear as an alternative for the modeling of discrete variables, mainly reservoirs with mosaic architecture of facies. In this dissertation, the reader is introduced to the stochastic modeling by MRFs in a generic sense. The main aspects of the technique are reviewed. MRF Conceptual Background is described: its characterization through the Markovian property and the equivalence to Gibbs distributions. The framework for generic modeling of MRFs is ...

1998-02-01

The IRG protein Irgm3 preserves cell survival during coxsackievirus B3 (CVB3) infection. However, the molecular mechanisms are not clear. Here, we examined the effect of Irgm3 expression on ER stress triggered by pharmacological agents or CVB3 infection. In Tet-On/Irgm3 HeLa cells, Irgm3 expression suppressed either chemical- or CVB3-induced upregulation of glucose-regulated protein78. Further, Irgm3 strongly inhibited the activation of both the PERK and ATF6 pathways of ER stress responses, which further led to the diminished phosphorylation of eIF2?, reduced cleavage/activation of transcription factor SREBP1 and attenuated induction of proapoptotic genes CHOP and GADD34. These data were further supported by experiments using Irgm3 knockout mouse embryonic fibroblasts, in which the ER stress induced by CVB3 was not relieved due to the lack of Irgm3 expression. In addition, the tunicamycin-triggered ER stress promoted the subsequent CVB3 infection. The effect of ...

2011-10-10

Reactive biomolecular divergence in genetically altered yeast cells and isolated mitochondria as measured by biocavity laser spectroscopy : a rapid diagnostic method for studying cellular responses to stress and disease.

Characterisation of thin films on rough steel substrates by FTIR microscopy and imaging

We report an analysis of four strains of baker's yeast (Saccharomyces cerevisiae) using biocavity laser spectroscopy. The four strains are grouped in two pairs (wild type and altered), in which one strain differs genetically at a single locus, affecting mitochondrial function. In one pair, the wild-type rho+ and a rho0 strain differ by complete removal of mitochondrial DNA (mtDNA). In the second pair, the wild-type rho+ and a rho- strain differ by knock-out of the nuclear gene encoding Cox4, an essential subunit of cytochrome c oxidase. The biocavity laser is used to measure the biophysical optic parameter Deltalambda, a laser wavelength shift relating to the optical density of cell or mitochondria that uniquely reflects its size and biomolecular composition. As such, Deltalambda is a powerful parameter that rapidly interrogates the biomolecular state of single cells and mitochondria. Wild-type cells and mitochondria produce Gaussian-like distributions ...

2006-12-01