Science.gov (United States)

PMID:8677780

UK PubMed Central (United Kingdom)

The ultrastructure of conjunctival melanocytic lesions in 49 patients was evaluated to find significant differences between benign and malignant cells. The patients studied included 9 with benign epithelial...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Intact rat fat cell exposed to 12.5 ..mu..M (..gamma..-32P)ATP incorporate label into specific proteins within minutes. By solubilizing the reaction mixture with SDS which bypasses the subcellular fractionation steps, the labeled proteins can be identified in autoradiographs of SDS-PAGE gels. The most prominently labeled protein has an M/sub r/ of 42,000. Localization of this component to the cell surface can be made on the basis of inhibition of phosphorylation by addition of a protein derived from the rat brain with protein kinase inhibitory property, susceptibility of the phosphorylated protein to the tryptic digestion, inhibition of phosphorylation of this protein after brief exposure to melittin. To rule out the possibility that the cell surface protein might be a mitochondrial contaminant from broken cells, /sup 32/Pi-labeled and (..gamma..-/sup 32/P)ATP-labeled cells were chromatographed on a rabbit anti-pyruvate dehydrogenase ...

International Nuclear Information System (INIS)

Anti-carcinoembryonic antigen monclonal antibody (MAb) CEA 102 was produced by immunization with purified CEA and the specific accumulation of radiolabeled CEA 102 in colorectal cancers was investigated by autoradiography of sugical specimens using Fuji Computed Radiography (FCR). Five patients with colorectal cancer were injected intravenously with "1"3"1I-labeled intact CEA 102 or its F(ab')_2. Primary tumor and liver metastases were successfully detected by external scanning with a gamma camera in 4 cases. Autoradiographic study of the surgical specimens using FCR showed predominant localization of "1"3"1I-labeled CEA 102 in primary tumors and liver metastases in all cases. Even a small liver metastasis (0.5 cm) was clearly visualized in the autoradiogram by FCR. The pixel distribution curves of the density of the respective tissues in the autoradiograms by FCR showed the heterogeneity of the distribution of administreted radiolabeled MAb in ...

International Nuclear Information System (INIS)

The extracellular matrix (ECM) of the distal tissues in a newt limb stump is completely reorganized in the 2-3-week period following amputation. In view of numerous in vitro studies showing that extracellular material influences cellular migration and proliferation, it is likely that the changes in the limb's ECM are important activities in the process leading to regeneration of such limbs. Using biochemical, autoradiographic, and histochemical techniques we studied temporal and spatial differences in the synthesis of glycosaminoglycans (GAGs) during the early, nerve-dependent phase of limb regeneration. Hyaluronic acid synthesis began with the onset of tissue dedifferentiation, became maximal within 1 weeks, and continued throughout the period of active cell proliferation. Chondroitin sulfate synthesis began somewhat later, increased steadily, and reached very high levels during chondrogenesis. During the first 10 days after amputation, distributions of sulfated ...

UK PubMed Central (United Kingdom)

Populus yunnanensis was employed as a model species to detect sexual differences in growth, physiological, biochemical, and ultrastructural responses to cadmium (Cd) stress, nitrogen...Full Text Available

UK PubMed Central (United Kingdom)

Exercise-training might be a logical method to reverse muscle atrophy and weakness in patients treated with glucocorticoids. The purpose of the present investigation was to establish whether a treatment...Full Text Available

UK PubMed Central (United Kingdom)

Corneal biopsy specimens from 3 patients with Cogan's microcystic corneal dystrophy were examined by light and electron microscopy. Specimens were taken from corneas showing microcysts, geographic or...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

The effect of ionizing radiation (2, 5, and 10 KGy of gamma rays) on muscle ultrastructure of grass shrimps (Penaeus monodon Fabricius) tails at ambient or frozen (-18{sup 0}C) temperature was investigated by transmission electron microscopy (TEM). No significant change was found in muscle ultrastructure of shrimp meat irradiated at doses of 2 or 5 KGy and then stored at 4{sup 0}C for 0 and 8 days. However, in shrimps which were irradiated at ambient temperature at a dose of 10 KGy, the margin of A-band of the myofibrils in longitudinal sections exhibited an irregular zig-zag pattern. In cross section some myosin filaments in the A-band regions were missing. A possible interpretation of these results would be that 10 KGy gamma irradiation dose at ambient temperature depolymerized myosin in the A-band from the tail of thick filament. Actin damage was also observed in some cross sections. Irradiation damage of sarcoplasmic membranes appeared in ...

DEFF Research Database (Denmark)

The temporal development of the effect of THIP (4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-ol) on the ultrastructure composition and GABA receptor expression in cerebellar granule cells was investigated by quantitative electron microscopy (morphometric analysis) and GABA binding assays. It was found that the cytoplasmic density of smooth endoplasmic reticulum was decreased, while the cytoplasmic density of rough endoplasmic reticulum, Golgi apparatus, vesicles and coated vesicles was greatly enhanced after exposure of the cells to THIP (150 microM) for only 1 hr. In cerebellar granule cells exposed to THIP (150 microM) for 3 hr low affinity GABA receptors were induced. These findings show that the effect of THIP on the ultrastructure composition and GABA receptor expression in cultured cerebellar granule cells may be interrelated and moreover it is likely that the turn-over of GABA receptors is extremely fast.

British Library Electronic Table of Contents (United Kingdom)

The present study was aimed at investigating effects of nickel (NiCl2) on secretion of testosterone (T), cell viability, ultrastructure and apoptosis in mouse Leydig cells. Testosterone release was measured after 48h of culture with 15.67, 31.25, 62.5, 125, 250, 500 and 1000mmol/L NiCl2 or without NiCl2 using radioimmunoassay. Cell viability was assessed by a MTT (metabolic activity assay). Quantification of apoptotic cells was performed using TUNEL assay and the ultrastructural changes were analyzed using transmission electron microscopy. The viability was decreased after addition of >=250mmol/L NiCl2. A concentration-dependent depression of T production was observed. The percentage of apoptotic cells was significantly increased only after addition of 125, 250 and 1000mmol/L NiCl2. After ...

UK PubMed Central (United Kingdom)

To study the role in AIDS pathogenesis of the human immunodeficiency virus type 1 (HIV-1) Tat protein, a transactivator of viral and cellular genes, we generated transgenic mice with a recombinant DNA...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

The autoradiographic appearance of the gastric mucosa, 5 hours after administration of indomethacin, was investigated in 29 adult rats. Indomethacin induced superficial gastric erosions. Autoradiography demonstrated the presence of viable gastric cells (as deduced by their ability to incorporate 3H-cytidin, an RNA precursor) not only in the mucosa without erosions, but also in the mucosa underneath the superficial erosions. The results indicate that indomethacin induced gastric erosions are not the superficial expression of a necrotic process taking place in the full thickness of the gastric mucosa at a particular site. A lumen-borne mechanism appears to be responsible for the formation of erosive areas in the mucosa.

Science.gov (United States)

The hydrozoa life cycle is characterized, in normal conditions, by the alternation of a post-larval benthic polyp and an adult pelagic medusa; however, some species of Hydrozoa react to environmental stress by reverting their life cycle: i.e. an adult medusa goes back to the juvenile stage of polyp. This very uncommon life cycle could be considered as some sort of inverted metamorphosis. A morphological study of different stages during the reverted life cycle of Turritopsis nutricula led to the characterization of four different stages: healthy medusa, unhealthy medusa, four-leaf clover and cyst. The ultrastructural study of the cellular modifications (during the life cycle reversion of T. nutricula) showed the presence of both degenerative and apoptotic processes. Degeneration was prevalent during the unhealthy medusa and four-leaf clover stages, while the apoptotic rate was higher during the healthy medusa and cyst stages. The significant presence of degenerative ...

Energy Technology Data Exchange (ETDEWEB)

Although the intracellular ultrastructural processing of epidermal growth factor (EGF) and its receptor have been described in cell culture systems, very few studies have examined this phenomenon in intact tissues. We have examined the ultrastructural and biochemical handling of (/sup 125/I)EGF in the epidermis and hair follicle bulb of intact, viable, 3- to 5-day-old rat skin the EGF receptor distribution of which has already been documented and in which EGF has been shown to be biologically active. After incubation of explants with 10 nM (/sup 125/I)EGF for 2.5 h at 25 degrees or 37 degrees C, radiolabel was detected over the basal cells of the epidermis and hair follicle outer root sheath, confirming previous light microscope observations. More specifically, silver grains were observed near coated and uncoated plasma membrane and coated membrane invaginations, Golgi apparatus, lysosomal structures, and nuclei. Sodium azide inhibited ...

British Library Electronic Table of Contents (United Kingdom)

The mature spermatozoon of Cricocephalus albus is filiform, tapered at both ends and shows the following features: 2 axonemes of different lengths presenting the 9+''1'' trepaxonematan pattern, 2 bundles of parallel cortical microtubules, a mitochondrion and a nucleus. Nevertheless, the particularity of the spermatozoon of C. albus is its anterior extremity with an apical electron-dense material associated with extramembranar ornamentation, a cytoplasmic dorsolateral expansion and spine-like bodies. To our knowledge, such an anterior extremity of the spermatozoon has not previously been described from a species of the superfamily Pronocephaloidea. Our study provides new data on the mature gamete of C. albus in order to improve our understanding of the pronocephaloidean phylogenetic relatio...

British Library Electronic Table of Contents (United Kingdom)

Actinidia deliciosa endosperm-derived callus culture is stable over a long period of culture. This system was used to investigate the ultrastructure of extracellular matrix occurring in morphogenic tissue. Specimens were prepared by different biological techniques (chemical fixation, liquid nitrogen fixation, glycerol substitution, critical-point drying, lyophilization) and observed by scanning electron microscopy (SEM). Fresh and wet samples were analyzed with the use of environmental scanning electron microscopy (ESEM). Extracellular matrix was observed on the surface of cell clusters as a membranous layer or reticulated network, shrunken or wrinkled, depending on the procedure. Generally, shrunken membranous layers with a globular appearance and fibrils were noted after critical-point d...

British Library Electronic Table of Contents (United Kingdom)

Shoot tips with 3-4 leaf primordia were excised from in vitro-grown sweetpotato plants (Ipomoea batatas) infected with little leaf phytoplasma (Candidatus Phytoplasma aurantifolia) and subjected to cryotherapy. All plants regenerated from the cryo-treated shoot tips were free of phytoplasma, whereas shoot tip culture or dehydration of shoot tips without subsequent cryotherapy resulted in phytoplasma-free plants at a frequency of only 7-10%. Histological and ultrastructural studies with light and transmission electron microscopy, respectively, indicated that cryotherapy was lethal to all cells except those in the apical dome of the meristem and the two youngest leaf primordia. These surviving parts of the shoot tip contained vascular tissue and sieve elements, but electron microscopy showed...

International Nuclear Information System (INIS)

... AND NUCLEAR MEDICINE biological localization cardiovascular diseases

International Nuclear Information System (INIS)

It is now known that various growth factors may also act in the central nervous system. Among them, it has recently been shown that epidermal growth factor (EGF) and insulin-like growth factor I (IGF-I) may possess trophic effects in the mammalian brain. We report here on the respective autoradiographic distribution of ["1"2"5I]EGF and ["1"2"5I]IGF-I receptor binding sites in the rat brain, both during ontogeny and in adulthood. It appears that ["1"2"5I]EGF sites are mostly found in the rat forebrain during brain development. On the other hand, ["1"2"5I]IGF-I sites are more widely distributed both during ontogeny and in adulthood. These results reveal the plasticity of the expression of EGF and IGF-I receptor sites in the mammalian brain. This could be relevant for the respective role of these two growth factors in the development and maintenance of neuronal function.

International Nuclear Information System (INIS)

The mechanism of trypsin inactivation by intact Hymenolepis diminuta has been investigated by biochemical and autoradiographic methods. Although worms inactivate trypsin and chymotrypsin in vitro, no inactivation of other endoproteases (subtilisin, pepsin and papain) could be demonstrated. Trypsin inactivation, as demonstrated by macromolecular substrates (azoalbumin, hemoglobin and casein), could not be detected using low molecular weight synthetic substrates such as N-p-benzoyl-DL-arginine-p-nitroanilide (BAPA) or N-p-tosyl-L-arginine methyl ester (TAME). In addition, the kinetic parameters (K/sub m/ and k_3) for H. diminuta-inactivated trypsin, using BAPA as the substrate, were not different from those of the native enzyme. The number of active sites for both native and inactivated trypsin were determined by titration with p-nitro-phenyl-p'-guanidinobenzoate. Absorbance values for both titrations were found to be identical. Dialysis, heating to 50 C, or repeated ...

International Nuclear Information System (INIS)

Using a radioactive tracer method the bulk and grain boundary diffusion of "5"9Fe was determined in industrial alloy 800 and melts of alloy 800 with additional P and S in the temperature range 800 to 1000 C. The use of the approximation of Suzuoka was confirmed by autoradiographs. In alloy 800 H the activation energy of grain boundary diffusion of "5"9Fe is (209 #+-# 17)kJ/mol. Dissolved elements especially P increase the activation energy of the grain boundary diffusion of Fe by their segregation to the grain boundaries. In addition the influence of the grain boundary diffusion on the growth of creep cavities was investigated in the same materials, and the chemical composition of the creep cavities and grain boundaries were analysed by Auger electron spectroscopy (AES). For alloy 800 + 0.088 wt-%P an enrichment of about 14 at-%P was observed at the grain boundaries. The addition of P clearly enhances the creep strength of alloy 800; this can probably be explained ...

UK PubMed Central (United Kingdom)

Addition of a vasoconstrictor to a local anesthetic may have several beneficial effects: a decrease in the peak plasma concentration of the local anesthetic agent, increase in the duration and the quality...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

Abstract Elongate plasmodia with myxosporean spores belonging to the genus Unicapsula, Davis, 1924 were found in the skeletal muscle of the striped seabream, Lithognathus mormyrus (L.), a candidate for the mediterranean aquaculture. The only species of Unicapsula described from the Mediterranean is Unicapsula pflugfelderi Schubert et al. 1975, which occurs in the picarel, Spicara smaris (L.). For morphological and molecular comparison of U. pflugfelderi from S. smaris with Unicapsula sp. from L. mormyrus measurements of plasmodia and spores, ultrastructural details and 18S and 28S rDNA sequences were analysed. Whereas plasmodia were 2-3 times larger in S. smaris than in L. mormyrus (length 2.47-0.81 mm; width 0.22-0.09 mm; P = 0.000), spore morphology showed minor differences and both 18S ...

British Library Electronic Table of Contents (United Kingdom)

A study has been carried out to investigate whether the action of triclabendazole (TCBZ) against Fasciola hepatica is altered by inhibition of drug metabolism. The cytochrome P450 (CYP 450) enzyme pathway was inhibited using ketoconazole (KTZ) to see whether a TCBZ-resistant isolate could be made more sensitive to TCBZ action. The Oberon TCBZ-resistant and Cullompton TCBZ-susceptible isolates were used for these experiments. The CYP 450 system was inhibited by a 2-h pre-incubation in ketoconazole (40??M), then incubated for a further 22?h in NCTC medium containing either KTZ, KTZ?+?nicotinamide adenine dinucleotide phosphate (NADPH) (1?nM), KTZ?+?NADPH?+?TCBZ (15??g/ml), or KTZ?+?NADPH?+?triclabendazole sulphoxide (TCBZ.SO; 15??g/ml). Changes to fluke ultrastructure following drug treatmen...

Energy Technology Data Exchange (ETDEWEB)

In a theory where the local observables are determined by local field algebras as the fixed points under a (a priori noncommutative) group of gauge transformations of the first kind, we show that, if the field algebras possess intermediate type I factors, we can construct observables having the meaning of local charge measurements, and local current algebras in the field algebras.

Energy Technology Data Exchange (ETDEWEB)

This is a description of the preliminary local design specifications of the Central Computing Network Security Controller. The external interface to the Central Computing Network is not described, but the functions and services to be provided are included as justification for the local design.

Energy Technology Data Exchange (ETDEWEB)

No abstract prepared.

Science.gov (United States)

... of a secondary standard (VCO) locally available. ... phase of the local secondary standards to the 10-min average of the phase of ... I3a - - \\.-e-~--. ...

Science.gov (United States)

... dartevellei is only known from the type locality (Matadi, Lower Congo River basin) and it has only ... the type locality is in the region of Matadi, and not only of Matadi itself. If there ... ...

International Nuclear Information System (INIS)

Regional arterial CO2 tension (PaCO2) reactivity of cerebral blood flow (CBF) and the effect of PaCO2 on the spatial and temporal heterogeneity of CBF were investigated by using autoradiographically determined CBF in the rat middle cerebral artery occlusion model after a 2-h period under pentobarbital anesthesia to clarify the relation between PaCO2 reactivity, CBF heterogeneity, and the temporal cycling of CBF. PaCO2 was adjusted to one of four levels. CBF was determined in four cortical areas and white matter using the tissue fractionation of [14C]iodoantipyrine [( 14C]IAP) in combination with vessel mapping using in vivo 4% thioflavine S. Specific PaCO2 reactivity and CBF were normal in the nonischemic cortex, normal, although slightly depressed, in the border zone far from the ischemic core area, and depressed in the border zone adjacent to the ischemic core area (P less than 0.001) and the ischemic core (P less than 0.001). In normocapnic and hypocapnic ...

Science.gov (United States)

... the type locality on the Zaire River at Matadi, where it was first recorded in the 1940s ... ...

Science.gov (United States)

... Congo, Guinea Equatorial, and Angola. The record from Matadi from the Lower Congo and the type locality ... ...

Energy Technology Data Exchange (ETDEWEB)

This paper is concerned with the development and application of an analytical method for the performance prediction of air cooled condensers. A local analysis is employed in which the condenser is considered as a matrix of small basic heat transfer modules. For each element, local film coefficients for both the air and the condensing fluid are determined according to the existing local conditions, including the two-phase flow regime. The paper considers an application of the method to heat pump condensing.

Science.gov (United States)

ELECTRON MICROSCOPE STUDIES INTO THE MORPHOLOGY AND LOCALIZATION OF OMSK HEMORRHAGIC FEVER VIRUS IN INFECTED ...

International Nuclear Information System (INIS)

... americium 241 americium 242 americium 243 curium 242 environment local

Energy Technology Data Exchange (ETDEWEB)

The objective of this research is to study the effects of elevated ozone, carbon dioxide and their combination on ultrastructural, physiological and biochemical responses of Scots pine needles and how these effects are reflected to photosynthesis, carbohydrate and nutrient allocation and finally to shoot and root growth of trees. In addition the interactions of the studied trees and mycorrhizal fungi as well as insect herbivores are studied. The exposures have been running only for two growing periods and it seems necessary to continue the experiment over the third growing season in 1996. Since the analyses are partially incomplete, only preliminary conclusions are possible at the moment. The slightly increased shoot growth and needle width and increased amount of starch in chloroplasts point to the slight stimulating effect of elevated CO{sub 2} among the chamber treatments. Altogether the growth of the seedlings was best in the chamberless treatment indicating a ...

Energy Technology Data Exchange (ETDEWEB)

Since chlordecone (Kepone, CD) interferes with cardiac Na{sup +} ion translocases, we have studied CD effects on cardiac SR calcium pump activity. SR was isolated from heart ventricles of male Sprague-Dawley rats. Cardiac SR Ca{sup 2+}-ATPase, {sup 45}Ca-uptake and cAMP as well as calmodulin (CaM) dependent protein phosphorylation were measured. Ca{sup 2+}-ATPase was differentiated into low affinity and high affinity forms by measuring the activity using 50 and 0.7 {mu}M free Ca{sup 2+} respectively. CD in vitro inhibited {sup 45}Ca-uptake by SR in a concentration dependent manner with an IC50 value of 7 {mu}M and SR {sup 45}Ca-uptake was totally inhibited at 20-30 {mu}M CD. In agreement with this, both high affinity and low affinity Ca{sup 2+}-ATPases, which are involved in Ca{sup 2+} transport across membranes, were also inhibited by CD in a concentration dependent manner with IC50 values of 0.7 and 3.2 {mu}M respectively. Both Ca{sup 2+}-ATPase and {sup 45}Ca-uptake by cardiac SR ...

CERN Document Server

The emergence of nanoscience has increased the importance of experiments able to probe the very local structure of materials, especially for disordered and heterogeneous systems. This is technologically important; for example, the nanoscale structure of glassy polymers has a direct correlation with their macroscopic physical properties. We have discovered how a local, high frequency dynamic process can be used to monitor and even predict macroscopic behavior in glassy polymers. Polyvinylethylenes vitrified by different chemical and thermodynamic pathways exhibit different densities in the glassy state. We find that the rate and amplitude of a high frequency relaxation mode (the Johari-Goldstein process involving local motion of segments of the chain backbone) can either correlate or anti-correlate with the density. This implies that neither the unoccupied (free) volume nor the configurational entropy governs the ...

CERN Document Server

Relations between parameter rigidity of locally free Lie group actions on closed manifolds and the 1st leafwise cohomology of the orbit foliations are discussed. Some computational results of the leafwise cohomology are included.

UK PubMed Central (United Kingdom)

The treatment of locally advanced rectal cancer including timing and dosage of radiotherapy, degree of sphincter preservation with neoadjuvant radiotherapy, and short and long term effects of radiotherapy...Full Text Available

UK PubMed Central (United Kingdom)

A panel of 16 monoclonal antibodies recognizing M protein (M1) of influenza virus was generated. Competition analyses resulted in localization of 14 monoclonal antibodies to three antigenic sites. Three...Full Text Available

Science.gov (United States)

Page 1. Mt N Local Spatial Frequency Analysis N for Computer Vision N John Krumm and Steven A. Shafer CMU-RI-TR-90-1 1 JUNO0 8 199 0 ...

Energy Technology Data Exchange (ETDEWEB)

The purpose of this paper is to assess a new local air coolers model in ISAAC 2.0, as ISAAC 1.0 could model local air coolers only at two locations. In the new model, local air coolers up to twelve locations could be handled. Large LOCA and loss of feed water sequences were selected for the model comparison. Two cases were analyzed with ISAAC 2.0: one with 6 local air coolers in one of the fueling machine room and in the steam generator room, respectively, and the other with 3 local air coolers at both fueling machine room and 6 local air coolers in the steam generator room. The study assumes that the safety systems such as emergency core cooling system, shield cooling system and moderator cooling system are unavailable. According to the ISAAC 2.0 results, the new local air coolers model showed almost no difference between two cases. Also it ...

UK PubMed Central (United Kingdom)

This work reports the design of and experimentation with a topographically patterned cell culture substrate of variable local density and anisotropy as a facile and efficient platform to guide...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

UK Nirex has announced four sites which it wishes to assess for the disposal of low-level and short-lived intermediate-level radioactive wastes. There is local opposition at all four of the potential sites. (U.K.).

UK PubMed Central (United Kingdom)

One hundred and seventy-nine patients completed a questionnaire focusing on adverse reactions to dental local anesthetics as manifested by 16 signs and symptoms. Twenty-six percent of the participants...Full Text Available

CERN Document Server

We numerically demonstrate selective near-field localization determined by the polarization state of a single emitter coupled to plasmonic nano-cluster. Seven gold nanospheres are carefully arranged such that up to ten polarization states of the single emitter, including linear, circular, and elliptical polarizations, can be distinguished via the distinct field localization in four gaps. The ability to transform polarization state into field spatial localization may find application for single emitter polarization analysis.

KoreaScience (Korea)

Full Text Available

Science.gov (United States)

... should seek permission from the local governments and personnel assignment commissions to set up an import- export tax management office in ...

Science.gov (United States)

... The realization of directional audio technology in the cockpit may reduce visual workload, enhance the presentation of flight and threat information ...

Energy Technology Data Exchange (ETDEWEB)

No abstract prepared.

Energy Technology Data Exchange (ETDEWEB)

Localized corrosion has a stochastic character by nature. This character leads to an observed random behavior: fluctuations of the free potential, fluctuations of the current when a constant potential is maintained. This random signal, which is similar to an electric noise, can be analyzed either in the time domain by counting the events or in the frequency domain by measuring the power spectral density of the electrochemical noise. The experimental techniques developed for investigating the localized corrosion on the probabilistic point of view, i.e., statistical counting and power spectral density measurements, are discussed. Then the experimental results reported in the literature are reviewed in order to see what kind of parameters are accessible and how they can be related to the localized corrosion processes.

International Nuclear Information System (INIS)

Studies have been performed with an anti-osteogenic sarcoma monoclonal antibody 791T/36 and human tumour xenografts to examine some of the quantitative and kinetic aspects of tumour localization. The influence of variations in tumour size and site and antibody dose on the extent and rate of specific antibody localization have been examined, together with the site of intratumoural deposition of the antibody. (UK).

Science.gov (United States)

Effective localization of small magnets against a noisy, real world background can involve various methods to first identify the magnetic fields produced by the magnet of interest, then to filter out background noise, and then to analyze the available magnetic field data to localize the magnet. Here we discuss low cost techniques which allow localization of small magnets with field strengths in the milliGauss range against real world background fields in the range of hundreds of mG, which may be fluctuating by up to tens of mG. Such techniques allow magnet tracking to be used to localize catheters in place of more invasive and expensive methods, e.g. fluoroscopy, for a variety of applications, including drug infusion with peripherally inserted central catheters (PICCs), laser ablation (TMR, PTMR) and introduction of pacemaker leads.

Energy Technology Data Exchange (ETDEWEB)

The characteristics of the local magnetic shear, a quantity associated with high-mode-number ballooning mode stability, are considered in heliotron/torsatron devices that have a large Shafranov shift. The local magnetic shear is shown to vanish even in the stellarator-like region in which the global magnetic shear is positive. The reason for this is that the degree of the local compression of the poloidal magnetic field on the outer side of the torus, which maintains the toroidal force balance, is reduced in the stellarator-like region of global magnetic shear because the global rotational transform in heliotron/torsatron systems is a radially increasing function. This vanishing of the local magnetic shear is a universal property in heliotron/torsatron systems with a large Shafranov shift since it results from toroidal force balance in the stellarator-like global shear regime that is inherent to such ...

Energy Technology Data Exchange (ETDEWEB)

Low temperature Nonphotochemical Hole Burning (NPHB) Spectroscopy of the dye rhodamine 800 (MF680) was applied for the purpose of discerning differences between cultured normal and carcinoma ovarian surface epithelial (OSE) cells. Both the cell lines were developed and characterized at the Mayo Clinic (Rochester, MN), with the normal cell line having been transfected with a strain of temperature sensitive Simian Virus 40 Large T Antigen (SV40) for the purpose of extending the life of the cell culture without inducing permanent changes in the characteristics of the cell line. The cationic lipophilic fluorophore rhodamine 800 preferentially locates in in situ mitochondria due to the high lipid composition of mitochondria and the generation of a large negative membrane potential (relative to the cellular cytoplasm) for oxidative phosphorylation. Results presented for NPHB of MF680 located in the cells show significant differences between the two cell lines. The results are interpreted on ...

International Nuclear Information System (INIS)

Olfactory tract has been demonstrated to be an important portal for inhaled solid nanoparticle transportation into the central nervous system (CNS). We have previously demonstrated that intranasally instilled Fe_2O_3 nanoparticles could transport into the CNS via olfactory pathway. In this study, we investigated the neurotoxicity and size effect of repeatedly low-dose (130 #mu#g) intranasal exposure of nano- and submicron-sized Fe_2O_3 particles (21 nm and 280 nm) to mice. The biomarkers of oxidative stress, activity of nitric oxide synthases and release of monoamine neurotransmitter in the brain were studied. Our results showed that significant oxidative stress was induced by the two sizes of Fe_2O_3 particles. The activities of GSH-Px, Cu,Zn-SOD, and cNOS significantly elevated and the total GSH and GSH/GSSG ratio significantly decreased in the olfactory bulb and hippocampus after the nano- and submicron-sized Fe_2O_3 particle treatment (p < 0.05). The nano-sized Fe_2O_3 generally ...

International Nuclear Information System (INIS)

We show that a general variant of the Wick theorems can be used to reduce the time ordered products in the Gell-Mann and Low formula for a certain class on non local quantum field theories, including the case where the interaction Lagrangian is defined in terms of twisted products. The only necessary modification is the replacement of the Stueckelberg-Feynman propagator by the general propagator (the 'contractor' of Denk and Schweda) D(y-y';#tau#-#tau#')=(1)/i(#DELTA#_+(y-y')#theta#(#tau#-#tau#')+#DELTA#+(y'-y)#theta#(#tau#'-#tau#)), where the violations of locality and causality are represented by the dependence of #tau#,#tau#' on other points, besides those involved in the contraction. This leads naturally to a diagrammatic expansion of the Gell-Mann and Low formula, in terms of the same diagrams as in the local case, the only necessary modification concerning the Feynman rules. The ordinary local ...

International Nuclear Information System (INIS)

Purpose: Treatment results and the pattern of relapse were evaluated in the multimodal treatment of Ewing's sarcomas of the chest wall. Methods and Materials: In a retrospective analysis, 114 patients with non-metastatic Ewing's sarcoma of the chest wall were evaluated. They were treated in the CESS 81, CESS 86, or EICESS 92 studies between January 1981 and December 1993. The treatment consisted of polychemotherapy (VACA, VAIA, or EVAIA) and local therapy, either surgery alone (14 patients), radiotherapy alone (28 patients) or a combination of both (71 patients). The median follow-up was 46.6 months (range 5-170). A relapse analysis for all patients with local or combined relapses was performed. Results: Overall survival was 60% after 5 years, event-free survival was 50%. Thirty-seven patients had a systemic relapse (32.4%), 11 patients had a local relapse alone (9.6%), and 3 patients had a combined ...

Energy Technology Data Exchange (ETDEWEB)

This report deals with the renewable energies and the local development called the territory intelligence in action. Taking into account the place of the electricity in the french energy accounting and the part of the nuclear in its production, the local authorities have to act in the heat domain, which is the first energy need in France, far in front of the specific electricity (those which cannot be replace by other type of energy). But 80% of the heat is today covered by fossil energies. No actions to change this situation will be done without a real implication of the local government. The authors preconize an ambitious objective: cover 50% of the heat needs from renewable energies in the next generat This objective must rely on a program called ''alternative energies''. In this framework the authors provide recommendations on the implementation of the renewable energies as an ...

Science.gov (United States)

The bone mineral areal content and the ultimate compressive strength were determined in 109 lumbar vertebrae from 36 subjects. The bone mineral areal content was related to the number, shape, and localization of the Schmorl's nodes detected in the x-rayed and sectioned vertebral bodies. One type of node, irregular in shape and localization, occurred only in the vertebrae with low bone mineral areal content values and thus in vertebrae with relatively low compressive strength. A second type of Schmorl's nodes, regular in shape and localization, did not reflect any general weakness of the vertebral bodies. PMID:6623194

Energy Technology Data Exchange (ETDEWEB)

Energy conservation and local energy deposition are investigated in the context of coupled-particle (i.e., neutrons, gamma rays, and charged particles) transport analysis. For charged particles, the concept of group splitting the 1 = 0 transfer matrix to ensure both particle and energy conservation is introduced. Although these procedures are more complex than those found in the usual neutron or coupled-neutron gamma-ray problem, they yield a consistent approach for the calculation of local energy deposition.

CERN Document Server

We give a general local central limit theorem for the sum of two independent random variables, one of which satisfies a central limit theorem while the other satisfies a local central limit theorem with the same order variance. We apply this result to various quantities arising in stochastic geometry, including: size of the largest component for percolation on a box; number of components, number of edges, or number of isolated points, for random geometric graphs; covered volume for germ-grain coverage models; number of accepted points for finite-input random sequential adsorption; sum of nearest-neighbour distances for a random sample from a continuous multidimensional distribution.

Science.gov (United States)

The present contribution deals with the thermophoresis particle deposition and thermal radiation effects on the flow, heat and mass transfer characteristics in a viscous fluid over a semi-infinite vertical porous plate. The governing boundary layer equations are written into a dimensionless form by similarity transformations. The transformed coupled nonlinear ordinary differential equations are solved numerically by means of the fourth-order Runge-Kutta method with a shooting technique. The effects of different parameters on the dimensionless velocity, temperature, and concentration profiles are shown graphically. In addition, results for the local skin-friction coefficient, the local Nusselt number, and the local Sherwood number are tabulated and discussed.

Science.gov (United States)

"ID# ","Measurement ID Number " "DATE ","Date " "JDATE ","Julian Date " "TIME ", "Local Time " "GMT ","Greenwich Mean Time " "BAND ","Dielectric Probe Band ...

UK PubMed Central (United Kingdom)

Understanding the physical characteristics of the local microenvironment in which Mycobacterium tuberculosis resides is an important goal that may allow the targeting of metabolic processes...Full Text Available

Science.gov (United States)

... Congo. It is probable that the type locality Matadi is in error and is the location from ... specimens of this species have been collected between Matadi and Luozi. (click map to view...

UK PubMed Central (United Kingdom)

BackgroundWith the exception of vertebrates, most organisms have plasma membrane associated ammonium transporters which primarily serve to import a source of nitrogen for nutritional...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundABCA3 transporter (ATP-binding cassette transporter of the A subfamily) is localized to the limiting...Full Text Available

Science.gov (United States)

any locality that is now in the United States. The English fleet lies at anchor, the infantry troops having disembarked and are attacking the Spanish settlement on May 28 and 29,...

Science.gov (United States)

... The insu- lation between gate and nanowire is the high-k dielectric HfO2, deposited by atomic layer depo- sition (ALD). ...

Energy Technology Data Exchange (ETDEWEB)

Portal localization images for high-energy electron beam therapy are necessary to confirm the treatment field by comparing them with a simulation image obtained before treatment or portal verification images after treatment. In this study, portal localization images were acquired using the computed radiography (CR) system and bremsstrahlung X-rays generated in the electron beam irradiations. All images obtained with phantom and the irradiations of in the electron energy of 8, 10, 12 and 15 MeV were feasible for clinical use. The CR system used in this study included general diagnostic imaging cassette and storage phosphor plate, but none of other special devices. The system can usually supply portal localization images, which maintains the quality assurance of high-energy electron beam therapy. (author)

UK PubMed Central (United Kingdom)

During spermiogenesis, Drosophila melanogaster spermatids coordinate their elongation in interconnected cysts that become highly polarized,...Full Text Available

UK PubMed Central (United Kingdom)

Minimally invasive parathyroidectomy is the procedure of choice for primary hyperparathyroidism due to parathyroid adenoma. Localization of the offending adenoma in minimally invasive parathyroidectomy...Full Text Available

Science.gov (United States)

News Jobs Grants/Funding Families Prevention Diseases Regulations Preparedness Mental Health and Traumatic Events Find Local Mental Health Services Information for: Parents and...

International Nuclear Information System (INIS)

This paper investigates regional and age-related changes in metabolite ratios using image-localized H-1 MR spectroscopy in children. Twenty-seven children referred for MR imaging of the brain underwent localized H-1 MR spectroscopy with a Siemens 1.5-T whole-body imager. Localization to 2 x 2 x 2-cm volumes of interest was achieved with a stimulated-echo or spin-echo technique. Repetition times of 1,600 and 5,000 msec were used, with echo times varying between 68 and 270 msec. Total combined imaging and spectroscopy times were 90-120 minutes.

British Library Electronic Table of Contents (United Kingdom)

In this paper we focus on appearance features describing the manual component of Sign Language particularly the Local Binary Patterns. We compare the performance of these features with geometric moments describing the trajectory and shape of hands. Since the non-manual component is also very important for sign recognition we localize facial landmarks via Active Shape Model combined with Landmark detector that increases the robustness of model fitting. We test the recognition performance of individual features and their combinations on a database consisting of 11 signers and 23 signs with several repetitions. Local Binary Patterns outperform the geometric moments. When the features are combined we achieve a recognition rate up to 99.75% for signer dependent tests and 57.54% for signer indep...

UK PubMed Central (United Kingdom)

The tetrapeptide KDEL is commonly found at the C terminus of soluble proteins of the endoplasmic reticulum (ER), and it contributes to their localization by interacting with a receptor that recycles...Full Text Available

UK PubMed Central (United Kingdom)

Invasive fungal infections can be devastating, particularly in immunocompromised patients, and difficult to treat with systemic drugs. Furthermore, systemic administration of those medications...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

As a general approach to the problem of precursive behavior in alloys that undergo a displacive transformation, defect theories are becoming increasingly popular. However, the microscopic origin of the proposed defects is usually not considered. Yu and Anderson (1984) have argued that properties of strong-coupling superconductors, such as the A-15 compounds, imply a breakdown of Migdal's theorem (the adiabatic, or Born-Oppenheimer approximation for separation of electrons and phonons) in these systems. The electron-phonon coupling is so strong that it must be incorporated already in zeroth order. This is the basis for local phonon models, in which the electron-phonon coupling provides an effective double well potential for a localized group of atoms. The Yu-Anderson model and an analogous local Jahn-Teller model (Abell, 1983) are reviewed in connection with displacive transformations in strong-coupling alloys.

International Nuclear Information System (INIS)

... structure crystal-phase transformations fluorescence fluorescence spectroscopy

UK PubMed Central (United Kingdom)

The density of corn pollen on leaves of milkweed plants inside and outside of cornfields was measured in several studies from different localities. The purpose was to obtain a representative picture...Full Text Available

UK PubMed Central (United Kingdom)

In general, the etiologic factors of chronic paranasal sinusitis are systemic conditions such as nutrition, predisposition, allergy, and local factors such as nasal anatomic conditions. Among these...Full Text Available

UK PubMed Central (United Kingdom)

Carbohydrate-directed endocytosis is mediated by a receptor, the hepatic binding protein; it is responsible for the clearance of galactose-terminated glycoproteins from the circulation. This process...Full Text Available

Science.gov (United States)

... known about Bellamya leopoldvillensis. It is recorded from Matadi and Kinshasa, but the exact localities and habitat ... Kinshasa (Brown 1994). It has been collected from Matadi and Kinshasa It is known f...

Energy Technology Data Exchange (ETDEWEB)

By means of a global mode analysis of ideal MHD modes for Mercier-unstable equilibria in a planar axis L=2/M=10 heliotron/torsatron system with an inherently large Shafranov shift, the conjecture from local mode analysis for Mercier-unstable equilibria given in [N. Nakajima, Phys. Plasmas 3, 4556 (1996)] has been confirmed and the properties of pressure-driven modes, namely, ballooning modes and interchange modes, inherent to such three-dimensional systems have been clarified. The change of the local magnetic shear due to the Shafranov shift, which is related to toroidicity, reduces the field line bending stabilizing effects on ballooning modes. According to the degree of the reduction of the local magnetic shear by the Shafranov shift, the Mercier-unstable equilibria are categorized into toroidicity-dominant (strong reduction) and helicity-dominant (weak reduction) Mercier-unstable equilibria. Since the ...

UK PubMed Central (United Kingdom)

mRNP granules at adult central synapses are postulated to regulate local mRNA translation and synapse plasticity. However, they are very poorly characterized in vivo. Here, in Drosophila...Full Text Available

International Nuclear Information System (INIS)

Nuclear magnetic resonance results are presented for a number of NaCl-type compounds and cubic Laves-phase type compounds of uranium, neptunium, and plutonium. Special emphasis is placed on the Knight shift and spin-lattice relaxation time measurements and their interpretation in terms of localized or itinerant pictures of the 5f electrons. (author).

Energy Technology Data Exchange (ETDEWEB)

We study certain supersymmetry breaking deformations of linear dilaton backgrounds in different dimensions. In some cases, the deformed theory has bulk closed strings tachyons. In other cases there are no bulk tachyons, but there are localized tachyons. The real time condensation of these localized tachyons is described by an exactly solvable worldsheet CFT. We also find some stable, non-supersymmetric backgrounds.

International Nuclear Information System (INIS)

The results of 144 previously untreated cases of primary Ewing's sarcoma of bone are reported with a minimum follow-up of 5 years. This series was treated between 1972 and 1982 at Istituto Ortopedico Rizzoli with a combined therapy. The local control of the disease consisted of amputation (ten cases), resection followed by radiation therapy (35-45 Gy) (48 cases) and radiation therapy alone (40-60 Gy) (86 cases). Adjuvant chemotherapy, rigorously standardized, was performed according two different protocols: the first (85 cases treated in the period 1972-1978) consisted of vincristine (VCR) Adriamycin (doxorubicin) (ADM), and cyclophosphamide (EDX); the second (59 cases treated in the period 1979-1982) of VCR, ADM, EDX and dactinomycin (DACT). At a follow-up of 5 to 16 years (median, 9), 59 patients (41%) are continuously disease-free (CDF), 81 (56%) developed metastatic disease and/or local recurrence, and four (3%) had a second malignancy. ...

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...Keeping chickens: a beginner's guide : Directgov - Environment and greener living chickens, feeding chickens, egg marking, registering a ...flock, battery hens Chickens; Department for Environment, Food and Rural Affairs; Registrations; Animals; Livestock; Local government; Local ...authorities A guide for people keeping chickens on the laws for registering and feeding them, and how to spot key diseases. A ...guide for people keeping chickens on the laws for registering and feeding them, and how to spot key diseases. Keeping chickens: ...

International Nuclear Information System (INIS)

Elements Ti, Mn, Fe, Ni, Cu, Zn, Pb, Br, Rb and Sr were determined by the method of radionuclide X-ray fluorescence analysis with semiconductor detection in samples of Taraxacum officinale from various localities of Bratislava. The dependence of their content on the source and the degree of the air pollution was found out. (author).

Energy Technology Data Exchange (ETDEWEB)

Implementing a successful local area network for a publications work-group isn't as simple as the scarcity of information on the subject would suggest. Making a network work for your requires careful planning, developing and acquiring network expertise, transforming your group's patterns of working together, and carefully managing the human and technological resources.

International Nuclear Information System (INIS)

We report the implementation of positron wave function and lifetime calculations in the all-electron full-potential linearized augmented plane wave method. Calculations of lifetimes for more than 30 materials with two different forms of the enhancement factor were done and compared to prior calculations and experiment. We find that reasonable agreement with experiment can be obtained within the local density approximation when all-electron full-potential calculations are done.

Energy Technology Data Exchange (ETDEWEB)

Electrochemical cyclic potentiodynamic polarization (CPP) experiments were performed on several candidate high-performance waste package container materials to evaluate their susceptibility to localized corrosion in aqueous environments relevant to the potential underground high-level nuclear waste repository. This paper presents the results of this study showing the effects of chloride ion (Cl) concentrations, pH, temperature, and electrochemical potential scan rate on the pitting corrosion behavior of these materials.

Energy Technology Data Exchange (ETDEWEB)

Three book reviews and five essays address the problems of governing coastal regions. The books reviewed and the articles covered the institutions and programs involved in resource management, the balance of local and state interests in coastal conservation and developments, a consensus on coastal planning issues, and a growing trend in state-local collaborative planning. Four of the articles pertain to California, and one focuses on programs in Maine, Rhode Island, and Washington. 135 references. (DCK)

CERN Document Server

We show that tilting a model sandpile that has dynamic disorder leads to bistability and hysteresis at the angle of repose. Also the distribution of {\\it local slopes} shows an interesting dependence on the amount of tilt - weakly tilted sandpiles retain the quasi-continuous distributions of the steady state, while large tilt makes the distribution more discrete, with local slopes clustered round particular values. These observations are used to explain recent experimental results on avalanche shapes; we give a theoretical framework in terms of directed percolation.

UK PubMed Central (United Kingdom)

Histone-beta-galactosidase protein fusions were used to identify the domain of yeast histone 2B, which targets this protein to the nucleus. Amino acids 28 to 33 in H2B were required for nuclear localization...Full Text Available

International Nuclear Information System (INIS)

Observed 7-eV satellites in the XPS spectra of UGa_2 and other B-group compounds are shown to be due to two-hole final states as confirmed by existing Auger data. The presence of these satellites is an indication for a weak fd hybridization and, when compared to uranium--transition-metal compounds, increased 5f localization.

Energy Technology Data Exchange (ETDEWEB)

A micro-mechanistic understanding of bone fracture that encompasses how cracks interact with the underlying microstructure and defines their local failure mode is lacking, despite extensive research on the response of bone to a variety of factors like aging, loading, and/or disease. Micro-mechanical models for fracture incorporating such local failure criteria have been widely developed for metallic and ceramic materials systems; however, few such deliberations have been undertaken for the fracture of bone. In fact, although the fracture event in mineralized tissues such as bone is commonly believed to be locally strain controlled, until recently there has been little experimental evidence to support this widely held belief. In the present study, a series of in vitro experiments involving a double-notch bend test geometry are performed in order to shed further light on the nature of the local cracking ...

International Nuclear Information System (INIS)

We make the supergravity solutions describing the branes (D3 branes and D4 branes) localized within the D6 branes in the near core region of D6 brane. From the D=11 solutions (M3 branes and M4 branes with the Z_N identifications in the transverse space) we obtain the D=10 supergravity solutions of D3 branes localized within D6 branes and D4 branes localized within D6 branes by reducing the dimension down to D=10 along a circular direction of S"3 part of the transverse space. M3 brane solution leads to D=10 background representing D3 branes localized on D6 branes in the region close to the D6 branes core. M4 branes lead to the D4 branes localized on D6 branes in the region close to the D6 brane core.

International Nuclear Information System (INIS)

Nop25 is a putative RNA binding nucleolar protein associated with rRNA transcription. The present study was undertaken to determine the mechanism of Nop25 localization in the nucleolus. Deletion experiments of Nop25 amino acid sequence showed Nop25 to contain a nuclear targeting sequence in the N-terminal and a nucleolar targeting sequence in the C-terminal. By expressing derivative peptides from the C-terminal as GFP-fusion proteins in the cells, a lysine and arginine residue-enriched peptide (KRKHPRRAQDSTKKPPSATRTSKTQRRRR) allowed a GFP-fusion protein to be transported and fully retained in the nucleolus. When the peptide was fused with cMyc epitope and expressed in the cells, a cMyc epitope was then detected in the nucleolus. Nop25 did not localize in the nucleolus by deletion of the peptide from Nop25. Furthermore, deletion of a subdomain (KRKHPRRAQ) in the peptide or amino acid substitution of lysine and arginine residues in the subdomain ...

International Nuclear Information System (INIS)

Image subtraction techniques, in conjunction with [75Se]selenomethionine (75Se) scintigraphy, have recently been suggested to be a potentially valuable tool for localization of parathyroid abnormalities. With use of these techniques, we prospectively studied 15 patients scheduled for parathyroid operations. Postoperatively, all were normocalcemic. Anterior scintiscans of the neck were divided into quadrants, and regions of enhanced uptake were assigned to one or more quadrants. On this basis, by chance alone a minimum of 25% of single-gland enlargements would be assigned to the correct quadrant of the neck. We found that by use of 75Se scanning only 8 of 22 abnormal glands (36%) were assigned to the quadrant of the neck in which they were found intraoperatively. In no case was a clearly visualized focus of parathyroid activity encountered. These results do not justify the continued use of 75Se scintigraphy with or without image subtraction in the preoperative ...

British Library Electronic Table of Contents (United Kingdom)

Using longitudinal data from Ukraine we examine the extent of any long-lasting effects of exposure to the Chernobyl disaster on the health and labour market performance of the adult workforce. Variation in the local area level of radiation fallout from the Chernobyl accident is considered as a random exogenous shock with which to try to establish its causal impact on poor health, labour force participation, hours worked and wages. There appears to be a significant positive association between local area-level radiation dosage and perception of poor health, though much weaker associations between local area-level dosage and other specific self-reported health conditions. There is also some evidence to suggest that those who lived in areas more exposed to Chernobyl-induced radiation have sig...

Science.gov (United States)

We propose a quantum secure direct communication scheme based on non-orthogonal entangled pairs and local measurement. In this scheme, we use eight non-orthogonal entangled pairs to act as quantum channels. Due to the non-orthogonality of the quantum channels, the present protocol can availably prohibit from all kinds of valid eavesdropping and acquire a secure quantum channel. By local measurement, the sender acquires a secret random sequence. The process of encoding on the random sequence is identical to the one in one-time-pad. So the present protocol is secure. Even for a highly lossy channel, our scheme is also valid. The scheme is feasible with present-day techniques.

Energy Technology Data Exchange (ETDEWEB)

Natural radioactive materials are present in all geological rocks in varying amounts, they are easily mobilized in the environment, and can reach hazardous radiological levels under certain conditions, requiring precautions to be taken. The present study deals with 50 geological samples of local (Tushki and Kalabsha in upper Egypt) and imported (southeast Asia and Turkey) kaolin types. The samples were analyzed by gamma-ray spectroscopy using a HPGe detector. The activity concentrations of {sup 232}Th and {sup 238}U series and {sup 40}K and the contents (in ppm) are given. The radium equivalent activity varied from 187.8 to 10185.19 Bq/kg. {sup 137}Cs was found in a range of 0.23-8.53 Bq/kg, for the local samples. The kaolin in Tushki area was suitable for industrial use.

British Library Electronic Table of Contents (United Kingdom)

Many studies on multisensory processes have focused on performance in simplified experimental situations, with a single stimulus in each sensory modality. However, these results cannot necessarily be applied to explain our perceptual behavior in natural scenes where various signals exist within one sensory modality. We investigated the role of audio-visual syllable congruency on participants? auditory localization bias or the ventriloquism effect using spoken utterances and two videos of a talking face. Salience of facial movements was also manipulated. Results indicated that more salient visual utterances attracted participants? auditory localization. Congruent pairing of audio-visual utterances elicited greater localization bias than incongruent pairing, while previous studies have repor...

Energy Technology Data Exchange (ETDEWEB)

A noninvasive method is described for estimating local cerebral blood flow (LCBF) and local partition coefficients by means of computed tomographic scanning during inhalation of 30% stable xenon gas in oxygen. Time-dependent xenon concentrations in arterial blood and brain tissue during the wash-in and washout phases are used to calculate partition coefficients and LCBF values by means of a least-squares curve-fitting analysis. Control values for partition coefficient and LCBF obtained from control subjects with minor head trauma in the chronic stage were compatible with those in several past reports, and reproducibility was satisfactory. The theoretic grounds underlying this new method of curve-fitting analysis are discussed.

Science.gov (United States)

The local heat transfer coefficient distribution of a square channel with two opposite ribbed walls was determined. The square channel was connected to a sudden contraction entrance in order to simulate the inlet condition of the turbine blade cooling passages. The test channel was heated by thin stainless steel foils with a thickness of 0.000025 m, and instrumented with 180 thermocouples. The brass ribs of a square cross-section were glued periodically, in line, onto the top and bottom walls of the foil-heated channel in patterns to achieve the desired spacing and angle-of-attack. The local heat transfer coefficients on the smooth side and the ribbed side walls, at the channel entrance and the downstream regions, were measured for eight rib configurations and three Reynolds numbers (Re = 10,000, 30,000, and 60,000).

Energy Technology Data Exchange (ETDEWEB)

Electronic structure calculations frequently invoke periodic boundary conditions to solve for electrostatic potentials. For systems that are electronically charged, or contain dipole (or higher) moments, this artifice introduces spurious potentials due to the interactions between the system and multipole moments of its periodic images in aperiodic directions. I describe a method to properly handle the multipole moments of the electron density in electronic structure calculations using periodic boundary conditions. The density for which an electrostatic potential is to be evaluated is divided into two pieces. A local density is constructed that matches the desired moments of the full density, and its potential computed treating this density as isolated. With the density of this local moment countercharge removed from the full density, the remainder density lacks the troublesome moments and its electrostatic potential can be evaluated accurately ...

International Nuclear Information System (INIS)

Somatostatin receptor scintigraphy (SRS) is a valuable method for the detection of somatostatin receptor-positive lesions. Most gastrinomas (over-)express the somatostatin receptor subtype 2 which can be targeted by In-111 labeled Octreotide. Different studies show a high sensitivity of SRS for the localization and staging of gastrinomas. SRS seems to be superior to other non-invasive imaging modalities and has been proven to significantly contribute to patient management. However, the sensitivity depends on the size and exact localization of the tumors. Smaller lesions and lesions located in the duodenum show a significantly lower sensitivity. In any case, SRS belongs to the routine imaging procedure for gastrinomas for localization and staging and can also be used for evaluation of the tumor progression. (author)

International Nuclear Information System (INIS)

The EXAFS-study (Fe, Sn and Ge K-edges) of disordered by mechanical activation binary supersaturated nanocrystalline solid solutions Fe-Al, Fe-Ge, Fe-Sn and Fe-Si is presented. The EXAFS-spectra are processed by solving the inverse binary problem, using the EXAFS-spectrum of the Fe K-edge only or combining the EXAFS-spectra on two K-edges, Fe and Ge or Fe and Sn. The parameters of partial correlation functions indicate chemical short-range ordering, high local static distortions in the lattice, increasing with metalloid content. The macrostructure of other type is forming through an initial, 'local' stage within the bcc lattice.

Energy Technology Data Exchange (ETDEWEB)

Measurements of local mass fluxes of liquid, local number fluxes of the drop and local drop size distributions at various locations in the test column were made for wide ranges of liquid flow rates and gas flow rates. An empirical correlation for the volume mean diameter of the drop at the nozzle exit was proposed. Measurements of the rates of absorption of carbon dioxide from carbon dioxide-air mixtures with water sprays (physical absorption) and aqueous sodium hydroxide sprays (chemical absorption) were made for wide range so fluid flow rates, feed gas concentrations, and initial alkali concentrations. The observed dimensionless rates of absorption were compared with the theoretical values by assuming penetration model with second-order irreversible reaction. 11 refs., 7 figs.

CERN Document Server

The effective approach to quantum dynamics allows a reformulation of the Dirac quantization procedure for constrained systems in terms of an infinite-dimensional constrained system of classical type. For semiclassical approximations, the quantum constrained system can be truncated to finite size and solved by the reduced phase space or gauge-fixing methods. In particular, the classical feasibility of local internal times is directly generalized to quantum systems, overcoming the main difficulties associated with the general problem of time in the semiclassical realm. The key features of local internal times and the procedure of patching global solutions using overlapping intervals of local internal times are described and illustrated by two quantum mechanical examples. The choice of time is tantamount to a choice of gauge at the effective level and changing the clock is, therefore, equivalent to a gauge transformation. This ...

UK PubMed Central (United Kingdom)

SummaryTwo Caucasian males (57 and 70 years old) were referred to our attention with parasinus mucoceles, maxillary and frontal mucocele, respectively, that had eroded the orbital rim...Full Text Available

UK PubMed Central (United Kingdom)

IntroductionOut-of-school adolescents are often neglected when planning for tobacco prevention programmes whereas they are more vulnerable. Few studies exist in Nigeria about their...Full Text Available

UK PubMed Central (United Kingdom)

Clinically, 3 distinct stages of diabetic foot infection may be recognized: localized infection, spreading infection and severe infection. Each of these presentations may be complicated by osteomyelitis....Full Text Available

International Nuclear Information System (INIS)

Methods of algebraic quantum field theory are used to classify all field- and observable algebras, whose common germ is the U(1)-current algebra. An elementary way is described to compute characters of such algebras. It exploits the Kubo-Martin-Schwinger condition for Gibbs states. (orig.).

UK PubMed Central (United Kingdom)

Genetic defects in the dystrophin-associated protein complex (DAPC) are responsible for a variety of pathological conditions including muscular dystrophy, cardiomyopathy, and vasospasm. Conserved DAPC...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Three instruments for measuring local velocities in liquid-metal MHD experiments for fusion blanket applications are being evaluated. The devices are used in room-temperature NaK experiments to measure three-dimensional flow field patterns anticipated in complex blanket geometries. Hot film anemometry, a standard technique in ordinary fluids, is being used, as well as two developmental devices. One is called the Liquid Metal Electromagnetic Velocity Instrument (LEVI), and performs essentially as a local dc electromagnetic flow meter. The third device, a Thermal Transient Anemometer (TTA) is a rugged, yet relatively simple device, which measures local velocity through the mechanism of convective heat transfer, in some ways similar to hot-film anemometry. Results are presented showing the kinds of data collected this far with each instrument. Measurements include both local velocity measurements and some ...

UK PubMed Central (United Kingdom)

BackgroundPrevention of Chagas disease depends mainly on control of the insect vectors that transmit infection. Unfortunately, the vectors have been resurgent in some areas. It is...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundMicrovascular injury plays a key role in normal tissue radiation responses. Statins, in addition to their lipid-lowering effects, have vasculoprotective...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

The human zinc finger protein genes (ZFX/Y) were identified as a result of a systematic search for the testis-determining factor gene on the human Y chromosome. Although they play no direct role in sex determination, they are of particular interest because they are highly conserved among mammals, birds, and amphibians and because, in eutherian mammals at least, they have active alleles on both the X and the Y chromosomes outside the pseudoautosomal region. We used in situ hybridization to localize the homologues of the zinc finger protein gene to chromosome 1 of the Australian echidna and to an equivalent position on chromosomes 1 and 2 of the playtpus. The localization to platypus chromosome 1 was confirmed by Southern analysis of a Chinese hamster [times] platypus cell hybrid retaining most of platypus chromosome 1. This localization is consistent with the cytological homology of chromosome 1 between the two species. The ...

UK PubMed Central (United Kingdom)

Recurrent or primary carcinoma of the breast en cuirasse, which may involve the skin of the entire thorax and abdomen, cannot be controlled by means of surgery or conventional local irradiation. The...Full Text Available

Science.gov (United States)

Local cardiac glucose utilization (LCarGU) was quantified in the rat heart according to the Sokoloff model and local cardiac blood flow (LCarBF) according to the /sup 14/C-iodoantipyrine method. For quantitative autoradiography calibration curves for heart slices were performed. They differed from the brain calibration curves by 8%. The lumped constant was 0.377 in isolated working hearts. LCarGU and LCarBF could then be quantified in awake rats. At different locations mean LCarGU of different hearts varied from 85 to 200 ..mu..moles/100g/min and mean LCarBF from 390 to 831 ml/100g/min. The ratio subendocardial/subepicardial glucose utilization or blood flow was not systematically different from 1. The results indicate that glucose can be an important fuel in the heart of the awake rat, although its contribution to overall metabolism varies from animal to animal.

Science.gov (United States)

... Previous Topic Pain Next Topic Scars and wounds Prostheses Prostheses (pross-THEE-sees) are man-made substitutes ... covered by medical insurance (this includes wigs). Breast prostheses: Contact your local chapter of the American Cancer ...

UK PubMed Central (United Kingdom)

BackgroundThe long latent stage seen in syphilis, followed by chronic central nervous system infection and inflammation, can be explained by the persistence of atypical cystic and...Full Text Available

UK PubMed Central (United Kingdom)

Experience with visual objects leads to later improvements in identification speed and accuracy (“repetition priming”), but generally leads to reductions in neural activity in single-cell...Full Text Available

International Nuclear Information System (INIS)

This article is about the network security defence method and technique at IHEP. Including: the experience, research result and application in network outlet security, server security, local network security, network security monitoring and collecting evidence, anti-virus etc

UK PubMed Central (United Kingdom)

BackgroundAs the resident stem cells of skeletal muscle, satellite cells are activated by extracellular cues associated with local damage. Once activated, satellite cells will re-enter...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundIntrafractional motion results in local over- and under-dosage in particle therapy with a scanned beam. Scanned beam delivery offers the possibility to compensate target...Full Text Available

UK PubMed Central (United Kingdom)

The X-ray crystallographic structural determinations of synthetic estrogens and antiestrogens provide reliable information on the global minimum energy conformation of these molecules or a local minimum...Full Text Available

UK PubMed Central (United Kingdom)

Plant roots exhibit remarkable developmental plasticity in response to local soil conditions. It is shown here that mild salt stress stimulates a stress-induced morphogenic response (SIMR) in Arabidopsis...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Non-invasive methods are described for estimating local cerebal blood flows (LCBF) and local partition coefficients (Llambda) during inhalation of 30 % stable xenon gas (Xe) in oxygen during CT scanning. After the denitrogenation with pure oxygen breathing, 30 % Xe is inhaled for four minutes to minimize subanesthetic effects with a rubber facemask and the delivery system of Xe. Local time-..delta.. Hounsfield units curve during the Xe wash-in and wash-out phase is utilized in order to calculate Llambda and LCBF using a least squares curve fitting analysis. Calculated Llambda and LCBF with the new method manifested reasonable distribution between the grey and white matters, and reproducibility was excellent in our study. Several case studies of patients with cerebral infarction are presented to demonstrate the characterization of Llambda and LCBF patterns in various tissues and theoretical grounds underlying the new method ...

Science.gov (United States)

To perform the localization project of WOLSUNG reactor fuel, mass-production system of irradiation-stable and sound fuel pellet must be established. The following subjects have been carried out to set up CANDU fuel fabrication process for continuous produ...

UK PubMed Central (United Kingdom)

BackgroundThe various tasks of visual systems, including course control, collision avoidance and the detection of small objects, require at the neuronal level the dendritic integration...Full Text Available

UK PubMed Central (United Kingdom)

Type II collagen-induced arthritis (CIA) in mice is an autoimmune experimental model for rheumatoid arthritis. Susceptibility to CIA is associated with certain major histocompatibility complex class...Full Text Available

International Nuclear Information System (INIS)

The supply of electronic instrumentation and controlling (I and C) equipments in Daya Bay Nuclear Power Station depends on importation up to now, however, reliable supply of spare parts is presently threatened by many factors. Consequently, Daya Bay Nuclear Power Station tries to localize these equipments. According to a survey, China has possessed the ability to undertake the research, development and production of the I and C system in nuclear power independently. We propose that localization should firstly starts with the production of replacement board and parts for analogical I and C system, gradually leads to the substitution of system cabinet units, and finally realize the independent research, development and production of advanced digital main control system. A series of prominent problems of producing nuclear grade I and C equipments are focused on the designing, manufacturing, testing and reliability evaluation. In this paper, ...

International Nuclear Information System (INIS)

The local environment of Ca dopants in barium titanate, BaTiO_3, is investigated by Ca K-edge X-ray absorption near-edge structure (XANES) spectroscopy. In conjunction with experiments, first-principles calculations by two methods are systematically made. The projector-augmented wave (PAW) method is used to optimize the local structure and obtain the formation energy. The augmented plane wave plus local orbitals method is adopted to obtain theoretical XANES spectra. A comparison between experimental and theoretical XANES spectra shows that Ca dopants are located at the Ba"2"+ sites forming Ca"2"+. Formation energy calculations of Ca doped BaTiO_3 by the PAW method also give the same results. The Ca atom in BaTiO_3 is off-centering in comparison with the Ba site in BaTiO_3. The off-centering of Ca atom is newly revealed by the combination of XANES spectroscopy and first-principles DFT calculations.

International Nuclear Information System (INIS)

The present study was undertaken in 27 children with localized Ewing's sarcoma treated at our hospital. In 9 cases the lesion was central and in 18 peripheral. Treatment consisted of: 1) Chemotherapy with 6 drugs (vincristine, cyclophosphamide, methotrexate, bleomycin, dactinomycin and doxorubicin) for one year in all patients; 2) Radiotherapy in 24 patients at a dose of 30-40 Gy in the entire bone with a booster dose of 10-15 Gy in the lesion. In 7 patients debulking surgery was performed followed by irradiation. Two cases with tumor in expendable bones and one with extensive destructive lesion in the tibia underwent radical surgery. One patient suffered local recurrence (femur) and 6 developed distant metastases. The remaining 20 (74%) patients were alive and tumor-free after follow-up periods of 17-80 months. Among the 12 patients with extremity lesions who were alive, 7 (58%) had minimal or mild treatment sequelae, 2 moderate, and 3 severe ...

UK PubMed Central (United Kingdom)

BackgroundLarviciding is a key strategy used in many vector control programmes around the world. Costs could be reduced if larvicides could be manufactured locally. The potential...Full Text Available

UK PubMed Central (United Kingdom)

Cdc13 is a single stranded telomere binding protein that specifically localizes to the telomere ends of budding yeasts and is essential for cell viability. It caps the ends of chromosomes thus preventing...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundClinical studies suggest that local wall shear stress (WSS) patterns modulate the site and the progression of atherosclerotic lesions. Computational fluid dynamics (CFD)...Full Text Available

Science.gov (United States)

The endothelin-B (ETB) receptor is a G-protein-coupled receptor that binds endothelin ligands and is essential for the development of epidermal melanocytes and enteric neurons. Recent reports indicate that ETB is localized to nuclei in cardiac ventricular myocytes, although it has been thought that ETB is localized mainly on the plasma membrane. It remains unknown, however, whether this unique distribution of ETB occurs in other tissues. To elucidate the subcellular distribution of ETB in the intestine, we performed immunofluorescence of ETB in mouse intestine using a specific antibody. ETB-like immunoreactivity was detected in both the mucosal and muscle layers. In the mucosal layer, villous epithelial cells, stromal cells of the lamina propria, and cryptic cells were immunostained. Subcellularly, ETB is localized mainly to the nuclei of villous epithelial cells. In the muscle layer, immunoreactivity of ETB was ...

UK PubMed Central (United Kingdom)

Arbuscular mycorrhizal fungi (AMF) are ecologically important root symbionts of most terrestrial plants. Ecological studies of AMF have concentrated on differences between species; largely assuming...Full Text Available

UK PubMed Central (United Kingdom)

The outcome of various osteoprogenitor-cell transplantation protocols was assessed using Col1a1-GFP reporter transgenic mice. The model requires the recipient mice to undergo lethal total body irradiation...Full Text Available

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UK PubMed Central (United Kingdom)

Drosophila neuroblasts divide asymmetrically by aligning their mitotic spindle with cortical cell polarity to generate distinct sibling cell types. Neuroblasts asymmetrically localize...Full Text Available

International Nuclear Information System (INIS)

The measurement of two-phase flow parameters and development of constitutive relationships for the HANARO/MAPLE type finned fuel using Real-Time Neutron Radiography (RTNR) is discussed in this paper. A single element finned Fuel Element Simulator (FES) was used with R134a Freon as the working fluid. To observe the effect of a spacer device on void distribution, single pin tests were performed with and without a spacer. By analyzing the RTNR images using image processing, the effects of the spacer on the time-averaged and instantaneous void fraction distribution were studied. For the experimental results without a spacer, the time-averaged local void distribution is radially asymmetric and the degree of void fluctuation increases with a decreasing frequency along the heated channel, where the observed asymmetry may be caused by flow induced vibration. For the experimental results with a spacer, the spacer clearly limits any significant vibration and the ...

UK PubMed Central (United Kingdom)

The recent assembly of the silkworm Bombyx mori genome with 432 Mb on 28 holocentric chromosomes has become a reference in the genomic analysis of the very diverse Order of Lepidoptera....Full Text Available

International Nuclear Information System (INIS)

We analyse the relation between the exchange algebra and the separation of the chiralities in classical Toda field theory. We show that there exists a conformally covariant Bloch wave basis such that the two chiralities commute. In terms of this basis we then reconstruct the periodic and local solution of Toda field theory. (orig.).

International Nuclear Information System (INIS)

The increasing diffusion of small-scale energy systems within the distributed generation (DG) paradigm is raising the need for studying the environmental impact due to the different DG solutions in order to assess their sustainability. Addressing the environmental impact calls for building specific models for studying both local and global emissions. In this framework, the adoption of natural gas-fueled DG cogeneration technologies may provide, as a consequence of cogeneration enhanced overall energy efficiency and of natural gas relatively low carbon content, a significant reduction of global impact in terms of CO2 emissions with respect to the separate production of electricity and heat. However, a comprehensive evaluation of the DG alternatives should take into account as well the impact due to the presence of plants spread over the territory that could increase the local pollution, in particular due to CO and NOx, and thus could worsen the ...

UK PubMed Central (United Kingdom)

BackgroundNeuropathic pain (NP) is partially mediated by neuroinflammatory mechanisms, and also modulates local neurogenic inflammation. Dietary lipids, in particular the total amount...Full Text Available

UK PubMed Central (United Kingdom)

BACKGROUND. Diabetes can be effectively treated and monitored in general practice. Postgraduate medical education at a local level is required to support this strategic shift of medical care from hospital...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

A micro-mechanistic understanding of bone fracture thatencompasses how cracks interact with the underlying microstructure anddefines their local failure mode is lacking, despite extensive research nthe response of bone to a variety of factors like aging, loading, and/ordisease.

Science.gov (United States)

... east Nigeria) and has also been recorded from south west Cameroon. Only two records; that from Angola the locality ... east Nigeria) and has also been recorded from south-west Cameroon. It is inferred tha...

UK PubMed Central (United Kingdom)

Ribulose-1,5-bisphosphate carboxylase activity was found in endosperm of germinating castor bean seed Ricinus communis and was localized in proplastids. The endosperm carboxylase has...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

We calculate mass spectrum of CHS model deformed by an exactly marginal operator, and find that there are tachyons which are not localized in the target space. Similar deformation is discussed in another CFT which corresponds to separated NS5-branes. A condensation of the tachyons is briefly argued.

UK PubMed Central (United Kingdom)

Ewing sarcoma (ES) is the second most common type of primary bone malignancy in children and young adults. Survival rates for localized ES have improved to upwards of 70% with aggressive chemotherapy...Full Text Available

UK PubMed Central (United Kingdom)

The efficacy of beta-lactam antibiotics and amikacin alone and in various combinations against Pseudomonas aeruginosa was studied in a rabbit model simulating a closed-space infection in a locally neutropenic...Full Text Available

Science.gov (United States)

Measurement of local steam condensation rates of cocurrent stratified flow of steam and subcooled water was carried out at atmospheric pressure in a horizontal rectangular channel. The channel was constructed of stainless steel with pyrex glass windows, a...

UK PubMed Central (United Kingdom)

In methicillin-resistant Staphylococcus aureus, the methicillin resistance gene mecA is localized within a large chromosomal region which is absent in the methicillin-susceptible...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundWide resection with tumor-free margins is necessary in soft-tissue sarcomas to minimize local recurrence and to contribute to long-term survival. Information about treatment...Full Text Available

UK PubMed Central (United Kingdom)

RNA is involved in a variety of chromatin modification events, ranging from large-scale structural rearrangements to subtle local affects. Here, we extend the evidence for RNA–chromatin interactions...Full Text Available

UK PubMed Central (United Kingdom)

Backgroundoscillatory activity, which can be separated in background and oscillatory burst pattern activities, is supposed to be representative of local synchronies of neural assemblies....Full Text Available

UK PubMed Central (United Kingdom)

Objectives:The aim of this study was to analyze clinical records of dental patients attending the Dental Department at the University of Jordan Hospital: a teaching hospital in Jordan....Full Text Available

Energy Technology Data Exchange (ETDEWEB)

We develop a general framework for the formulation of the action principle and the noether theorem for classical noncommutative field theories. We give a concrete example of an algebra that fits into this framework. It describes a scalar field theory on noncommutative minkowski space. We develop a notion of locality for this algebra and investigate the locality properties of localised interaction terms. This leads us to the definition of local functionals on the field algebra. We propose a scheme for the quantisation of these functionals. (orig.) [German] Wir entwickeln eine allgemeinen rahmen, der es erlaubt, das wirkungsprinzip und das noether-theorem fuer klassische nichtkommutative feldtheorien zu formulieren. Als ein konkretes beispiel betrachten wir eine algebra, die sich in diesem rahmen einfuegt, und die eine skalare feldtheorie auf dem nichtkommutativen minkowski-raum beschreibt. Fuer diese algebra wird ein ...

UK PubMed Central (United Kingdom)

The repair process of damaged tissue involves the coordinated activities of several cell types in response to local and systemic signals. Following acute tissue injury, infiltrating inflammatory cells...Full Text Available

UK PubMed Central (United Kingdom)

Image enhancement is of great importance in medical imaging where image resolution remains a crucial point in many image analysis algorithms. In this paper, we investigate brain hallucination...Full Text Available

UK PubMed Central (United Kingdom)

PurposeTaxanes have effects on angiogenesis causing difficulties in separating biologic effects of chemotherapy from those due to angiogenesis inhibitors. This randomized...Full Text Available

Science.gov (United States)

Mar 1, 2011 ... The movement of hydrothermal fluids and/or fumarolic vapors through local rocks prior ... The Solar Energetic Particle Event of December 14, 2006 .... for measurement of non-precipitating cloud hydrometeors and aerosols, ...

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The goal of this project is to provide materials engineers, chemical engineers and plant operators with a software tool that will enable them to predict localized corrosion of process equipment including fabricated components as well as base alloys. For design and revamp purposes, the software predicts the occurrence of localized corrosion as a function of environment chemistry and assists the user in selecting the optimum alloy for a given environment. For the operation of existing plants, the software enables the users to predict the remaining life of equipment and help in scheduling maintenance activities. This project combined fundamental understanding of mechanisms of corrosion with focused experimental results to predict the corrosion of advanced, base or fabricated, alloys in real-world environments encountered in the chemical industry. At the heart of this approach is the development of models that predict the fundamental parameters ...

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The radiotherapy is the prime treatment for the cavum cancer. It is also useful to treat the tumor recurrences, in this case the reirradiation stays the only efficient therapy option to give a correct local control. The reirradiation, exclusive or in association with other therapies can contribute to the local control of cavum cancer recurrences with a survival rate at five years of 36 to 58%. (N.C.)

Wastenet

... Thursday: South Brisbane Sailing Club, Orleigh Park Hill End Terrace, West End. Friday: Booroodabin Bowls Club, 126 Breakfast Creek Road, Newstead. Related Photos Six months on: Kerrin Quinn's Story (Emma Sykes - ABC Local) Map Fernvale 4306 Subscribe/RSS Subscribe to ABC Brisbane videos Subscribe to all ABC Local videos Topics: disasters-and-accidents, floods Locations: brisbane-4000, fernvale-4306 Print page ...

International Nuclear Information System (INIS)

Purpose: We present an update analysis of the multiinstitutional Ewing's sarcoma study CESS 86. Methods and Materials: From January 1986 through June 1991, 177 patients with localized Ewing's sarcoma of bone, aged 25 years or less, were recruited. Chemotherapy consisted of four 9-week courses of vincristine, actinomycin D, cyclophosphamide, and adriamycin (VACA) in low-risk tumors (extremity tumors =# 100 cm"3). Local therapy was an individual decision in each patient and was either radical surgery (amputation, wide resection) or resection plus postoperative irradiation with 45 Gy or definitive radiotherapy with 60 Gy (45 Gy plus boost). Irradiated patients were randomized concerning the type of fractionation in either conventional fractionation (once daily 1.8-2.0 Gy, break of chemotherapy) or hyperfractionated split-course irradiation simultaneously with the VACA/VAIA chemotherapy (twice daily 1.6 Gy, break of 12 days after 22.4 Gy and 44.8 ...

Science.gov (United States)

Plasma generated in low-density vapor by a negative ion beam has been studied experimentally and computationally. We show that space charge neutralization of the beam occurs at very low vapor density, and that correspondingly the electron density may be much less than the beam and plasma ion densities. When there is a large local gas density, as in a charge changing cell, the resulting high electron density is also localized to the same region. Therefore, very few electrons will reach a negative ion accelerator even if it is placed one or two beam diameters from such a cell.

International Nuclear Information System (INIS)

Using Southern, dot-blot and 'in situ' hybridization, molecular and cytological localization of repetitive 'Lupinus lueteus' DNA sequence was shown. Under CsCl gradient centrifugation conditions CG-rich satellite fraction appeared. Dot-blot hybridization clearly indicated that 1070bp repetitive element being a member of previously described EcoRI fragments family appeared only in the main band. The use of that DNA fragment as an 'in situ' hybridization signal in the euchromatin area. (author). 26 refs, 3 figs.

Energy Technology Data Exchange (ETDEWEB)

A method based on cluster analysis techniques is proposed in order to obtain representative local wind patterns. Modeling renewable energy systems, in an accurate way which strongly depends on wind loads, requires reliable data to analyze their response and evaluate their performance. Otherwise poor agreement with the models may be obtained. In a case study for La Paz, Baja California Sur, Mexico, four different wind patterns were obtained from a one-year data set recorded at 10-min intervals. (author)

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A local Heine-Abarenkov model potential is proposed for zinc blende-type crystals. The potential parameters are determined by satisfying the zero pressure condition and the first zero of the empirical pseudopotential interpolated from band calculations. Two sets of parameters are presented for thirteen tetrahedral compounds such as AlP, AlAs, AlSb, GaP, GaAs, GaSb, InP, InAs, InSb, ZnS, ZnSe, ZnTe, and CdTe.

International Nuclear Information System (INIS)

Conduction-band electrons, formed by pulse radiolysis of Degussa P25 TiO_2 particles, have been monitored by time-resolved microwave conductivity and found to undergo equilibrium localization and eventual recombination at the particle surface. In the presence of isopropyl alcohol recombination is retarded due to surface hole scavenging. The particle bulk can then be pumped with mobile electrons, which survive for seconds.

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Use of a broadband Local Area Network (LAN) for transmission of classified and secure unclassified information requires monitoring capabilities which are sensitive to discrete segments of the network frequency spectrum. A viable monitoring system must be capable of detecting possible intrusion attempts or network malfunctions and alerting operating and security personnel. This report documents the results of an evaluation of the Magnavox CATV Systems Inc. Digital System Sentry software for network monitoring. Recommendations are made on its possible future role in broadband LAN security monitoring throughout the Nuclear Weapons Complex.

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The objective of the present study is to reveal thermal characteristic of microcapsulated lauric acid slurry in circular pipe. Test were performed with microcapsulated lauric acid slurry in a heating test section with a constant heat flux boundary condition. Local Nusselt number and the effective thermal capacity were measured. As the size of microcapsulated lauric acid were increased, local Nusselt number of microcapsulated lauric acid slurry were increased. The effective thermal capacity of microcapsulated lauric acid slurry was 0.5 times than it of water.

International Nuclear Information System (INIS)

The role of radiation therapy in local tumor control and decreased incidence of pulmonary metastasis is reported in 271 patients who were entered into the Intergroup Ewing's Sarcoma Study with more than one year follow-up and on whom all radiotherapy records were reviewed. The majority of the patients were irradiated to the primary tumor with doses of 4500 to 6500 rad in five to six weeks in combination with systemic administration of three drugs (vincristine, actinomycin-D and cyclophosphamide) or four drugs (vincristine, actinomycin-D, cyclophosphamide and adriamycin). One of the groups of patients was treated with three drugs and bilateral pulmonary irradiation (1500 rad, uncorrected dose, in two weeks). Preliminary analysis shows an overall local primary tumor control of 89%. Patients with lesions in the pelvis had a local failure rate of 17% (9 of 52) and in the humerus 23% (7 of 31). Factors affecting ...

International Nuclear Information System (INIS)

Purpose: To evaluate the outcomes of patients with Ewing's sarcoma family of tumors (ESFT) treated with modern radiotherapy techniques with MRI along with optimal chemotherapy. Methods and Materials: The records of all 60 patients with ESFT who received radiation to the primary site between 1990 and 2004 were reviewed. All patients received chemotherapy, including vincristine, doxorubicin, cyclophosphamide, ifosfamide, and etoposide. Radiation was used as the sole modality for local control in 31 patients and was given either before (n = 3) or after surgical resection (n = 26) in the remainder. All patients had MRI and CT scan-based treatment planning, and 43% received intensity-modulated radiation therapy. Radiation doses ranged from 30 Gy to 60 Gy (median, 51 Gy), and 35% received hyperfractionated radiotherapy. Results: Median age was 16 years (range, 2-40 years). Because of selection bias for radiotherapy, the majority of primary tumors were centrally located ...

Energy Technology Data Exchange (ETDEWEB)

Background and Purpose: In an earlier phase II study, irradiation together with razoxane was shown to improve local control in recurrent rectal cancer. Therefore, the Austrian Society of Radiooncology (OeGRO) initiated a randomized controlled trial in 1992 to compare this combined treatment versus radiation therapy alone. Patients and Methods: Between 1992 and 1999, 36 patients with localized recurrences of rectal cancer were randomized to receive radiotherapy without (group A) or with razoxane (group B). The prognostic variables of the two groups were similar except for a longer median latency period from initial surgery to local recurrence in group A. High-energy photons with daily fractions between 170 and 200 cGy were used. The median total radiation dose was 60 Gy in each group. The patients in group B received a median razoxane dose of 9.6 g (range, 5-12 g). Main outcome measures were local ...

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Gastric stromal tumors are an ill-defined group of lesions arising from muscle wall cells and characterized by extremely variable biological patterns. Thanks to modern immunohistochemical and ultrastructural techniques, four main classes of these lesions have been identified, namely: (1) tumors with differentiation toward smooth muscle cells; (2) tumors with differentiation toward neural elements; (3) tumors with differentiation toward neural elements; (3) tumors with dual differentiation toward either cell type. It was investigated the yield of CT in diagnosing and characterizing gastric stromal tumors. It was retrospectively reviewed the CT findings of 38 patients (15 men and 23 women; mean age 51 years) with pathologically proven gastric stromal tumors, namely 31 of myoid origin, 4 of neural origin, 2 with both muscle and neural differentiation, 1 lacking differentiation with either cell type. The myoid tumors involved gastric fundus in 9/13 and 5/7 benign ...

Energy Technology Data Exchange (ETDEWEB)

A field experiment was held in the northwestern Taiwan as a part of a long-term research program for studying Taiwan`s local circulation. The program has been named as Taiwan Regional-circulation Experiment (TREX). The particular goal of this research is to investigate characteristics of boundary layer and local Circulation and their impact on the distribution and Variation of pollutants in the northwestern Taiwan during Mei-Yu season. It has been known for quite sometime that land-sea breeze is very pronounced under hot and humid conditions. Extensive network includes 11 pilot ballon stations, 3 acoustic sounding sites, and 14 surface stations in about 20 km by 20 km area centered at National Central University, Chung-Li. In addition, there are ground temperature measurements at 3 sites, Integrated Sounding System (ISS) at NCU, air plane observation, tracer experiment with 10 collecting stations, 3 background upper-air sounding stations, 2 ...

Energy Technology Data Exchange (ETDEWEB)

We used the tissue distribution of ({sup 14}C)butanol to quantitate regional blood flow in the spinal cord (RSCBF) of pentobarbital-anesthetized, normothermic rats in which segmental local cooling pentobarbital-anesthetized, normothermic rats in which segmental local cooling of the spinal cord (to 25-28{degrees}C) at vertebral levels C4-C6 (n = 6) or T13-L1 (n = 6) was induced. Thirty minutes later, blood flow measurements were made at seven levels of the spinal cord and in the sciatic nerve trunks and biceps femoris muscles. Sham-cooled rats served as controls (n = 12). In control rats, RSCBF varied between 41.5 +/- 2.4 and 65.1 +/- 3.2 ml.min-1.100 g-1. Local cooling of the C4-C6 cord segment reduced RSCBF by 32%, from 65.1 +/- 3.2 to 44.4 +/- 3.5 ml.min-1.100 g-1 (P less than 0.01). Tissue vascular resistance (R) in the cooled C4-C6 segment was elevated versus control. There were no other changes in RSCBF at the other ...

International Nuclear Information System (INIS)

From 1981 up to February 1985, a total of 93 protocol patients entered the study CESS 81. The protocol recommended an initial 18-week period of polychemotherapy (VACA) followed by local therapy and two additional cycles of chemotherapy. Local therapy consisted either of radical surgery or of incomplete resection plus postoperative irradiation with 36 Gy or of radiotherapy alone (46 and 60 Gy). Centrally located lesions were always irradiated with 60 Gy. This article summarizes the data after 5 years. Data of 93 patients were analysed in October 1986 after a median follow-up of 37 months. The projected 5-year survival is 50%. The relapse rate was 42%, distant relapses occurred in 19%, local (plus distant) relapses in 23%. Most of the relapses occurred during the first 3 years of observation. Failure rate was high in patients undergoing irradiation alone (44%). Initial tumour mass (> 100 ml) and histopathologic response to ...

Energy Technology Data Exchange (ETDEWEB)

Tc-MDP 10mCi was intravenously given preoperatively to 20 patients with primary bone tumors and 1 with a metastatic bone tumor. Preoperative and postoperative scintigraphs of resected tumor and scintigraphs of sliced tumor were compared. Tissue fragments were collected from the sliced tumor, and RI measured to compare concentration rates at different areas. Histological investigations were also done. Localization of Tc-MDP was increased at sites of tumorous bone formation, of reactive bone formation at tumor edges, and of cartilage calcification, with little concentration at tumor cells or necrotic tissue. VX/sub 2/ carcinoma was transplanted into the rabbit tibia, Tc-MDP was intravenously injected when bone destruction was radiologically evident, and investigations were done as in the clinical cases. In experimental bone tumor, increased uptake localization of Tc-MDP was much the same as in clinical cases. Tetracycline was given to the rabbit ...

International Nuclear Information System (INIS)

In order to qualify corrosion resistant materials for high level waste (HLW) packagings acting as a long-term barrier in a rock salt repository, the corrosion behaviour of the preselected materials Ti 99.8-Pd, Hastelloy C4 and two unalloyed steels was investigated. The resistance of the materials to general corrosion, local corrosion and stress corrosion cracking was examined under postulated accident conditions in the repository by long-term immersion tests of up to 4 years duration and electrochemical methods. The parameters investigated were different salt brines, temperatures of 90 deg. C, 170 deg. C and 200 deg. C as well as a gamma radiation field of 10"3Gy/h (10"5rad/h). Among the materials studied, Ti 99.8-Pd exhibited the highest corrosion resistance. This material corroded at a very low rate (local corrosion and stress corrosion cracking. Hastelloy C4 ...

International Nuclear Information System (INIS)

Given the local observables in the vacuum sector fulfilling a few basic principles of local quantum theory, we show that the superselection structure, intrinsically determined a priori, can always be described by a unique compact global gauge group acting on a field algebra generated by field operators which commute or anticommute at spacelike separations. The field algebra and the gauge group are constructed simultaneously from the local observables. There will be sectors obeying parastatistics, and intrinsic notion derived from the observables, if and only if the gauge group is non-Abelian. Topological charges would manifest themselves in field operators associated with spacelike cones but not localizable in bounded regions of Minkowski space. No assumption on the particle spectrum or even on the covariance of the theory is made. However the notion of superselection sector is tailored to theories without massless ...