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Background The Committee for the Standardization of Renal Pathological Diagnosis and the Working Group for Renal Biopsy Database of the Japanese Society of Nephrology started the first nationwide, web-based, and prospective registry system, the Japan Renal Biopsy Registry (J-RBR), to record the pathological, clinical, and laboratory data of renal biopsies in 2007. Methods The patient data including age, gender, laboratory data, and clinical and pathological diagnoses were recorded on the web page of the J-RBR, which utilizes the system of the Internet Data and Information Center for Medical Research in the University Hospital Medical Information Network. We analyzed the clinical and pathological diagnoses registered on the J-RBR in 2007 and 2008. Results Data were collected from 818 patien...

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We conducted a retrospective review of the North American Renal Transplant Cooperative Study (NAPRTCS) Registry transplant and dialysis arms to assess anemia and growth patterns in children who returned to dialysis after a failed renal transplant from January 1, 1992 to February 3, 2004. Of the 1807 potential study subjects, 1451 had transplant removal data (TxIn vs. TxOut) available for analysis. Four hundred and twenty-one of 1451 patients (29%) had a transplant nephrectomy at the time of entry into the NAPRTCS Registry Dialysis arm. Anemia rates steadily decreased from 72.2% at 30 days after dialysis initiation to 59.5% at 12 months after dialysis initiation. Factors associated with anemia at 30 days after dialysis initiation included hemodialysis, lack of Epo use, and patients who comprised earlier study era cohorts. At one yr after return to dialysis, earlier study cohort era was the only factor ...

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Malignancies Breast Malignancies Bladder, Prostate, and Testicular Malignancies Uses of Cancer Registry Data Brain Tumor Reporting Training Materials Overview Presentation and...

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Percutaneous renal biopsy (PRB) is a safe and effective tool in the diagnosis and management of renal disease. It is the gold standard for evaluating renal parenchymal disease. It is both useful for...Full Text Available

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Diagnostic accuracy of the currently available serum markers of cardiac injury, such as myoglobin, creatine kinase and its myocardial isoform, are altered in patients with renal failure. It is shown...Full Text Available

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...ukDirect dial: 020 7630 4521 __________________...ukDirect dial: 020 7630 4515 __________________...ukDirect dial: 020 7630 4522 __________________...ukDirect dial: 020 7630 4519 __________________...

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The Agency for Toxic Substances and Disease Registry (ATSDR) is a public health agency with responsibility for assessing the public health implications associated with uncontrolled releases of hazardous...Full Text Available

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Malignancies Breast Malignancies Bladder, Prostate, and Testicular Malignancies Uses of Cancer Registry Data Brain Tumor Reporting Training Materials Overview Presentation and...

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Competitiveness of the UK furniture manufacturing industry.2010 ...is clear from the study that the UK furniture manufacturing industry has responded to the challenge of ...Competitiveness of the UK furniture manufacturing industry.2010

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The nephrotoxicity of cefoxitin was studied in a rat model of impaired renal function. Two levels of renal impairment were produced: "moderate," with blood urea concentrations of 100 to 150 mg/100 ml...Full Text Available

UK PubMed Central (United Kingdom)

Visual assessment of the degree of renal artery stenosis on renal arteriography has a large inter- and intraobserver variability. This degree is usually estimated by the ratio between the most narrowed...Full Text Available

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UK-ENGLAND/CLACTON-ON-SEA, R. COLNE, COAST, AGR.

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PMID:21710264

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The exact incidence of pineal germ-cell tumors is largely unknown. The tumors are rare, and the number of patients with these tumors, as reported in clinical series, has been limited. The goal of this...Full Text Available

International Nuclear Information System (INIS)

Aim: To create nomograms for renal size as measured from DMSA renal studies, and to test the nomograms for their ability to separate normal from abnormal kidneys. Method: Renal length was measured from posterior oblique views and renal area from posterior views. Results from 253 patients with bilateral normal kidneys were used to create nomograms for renal size relative to patient age, body height, weight or body surface area (BSA). The nomograms enclosed 95% of the normal kidneys, thus indicating the range for 95% confidence limits, and hence the specificity. Each nomogram was then tested against 46 hypertrophied kidneys and 46 damaged kidneys. Results: The results from nomograms of renal length and renal area, compared to age, body height, body weight and BSA are presented. For each nomogram, the range is presented as a fraction of the ...

International Nuclear Information System (INIS)

This 2001 edition of the guide to UK renewable energy companies examines the geothermal heat pump sector, and discusses the technology involved, installations of geothermal heat pumps, the activity in the UK market with increased interest in UK geothermal heat pump products from abroad, and developments in the building sector. The UK government's increased support for the industry including its sponsorship of the Affordable Warmth programme, and the future potential of ground source systems are discussed.

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Original holdings are now kept by the World Data Centre C1 at RAL: http://wdcc1. bnsc.rl.ac.uk MODS DOY = 246 ADID_REF Not applicable LOGICAL_FILE_ID ...

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A brief article considers the possible result of the enquiry into Nirex`s plan to build an underground rock laboratory at Sellafield in relation to radioactive waste disposal in the UK. (UK).

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on practical projects such as woodland management, limestone grassland management, cattle management, conflict management and education. ...Cathy Heaton Telephone 01772 892400 Email cenquiries@uclan.ac.uk www.uclan.ac.uk/schoolbne

UK PubMed Central (United Kingdom)

Albeit the considerable progress that has been made both in our understanding of the pathophysiology of acute renal failure (ARF) and in its treatment (continuous renal replacement therapies), the morbidity...Full Text Available

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Nine patients with renal osteodystrophy were tested for 6.5 to 35 months with 1,25-dihydroxycholecalciferol (1,25-DHCC). A close biochemical follow-up was performed during the first 6 months of treatment,...Full Text Available

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To study the relationship between vasopressin and the renal kallikrein-kinin system we measured the rate of excretion of kinins into the urine of anesthetized rats during conditions of increased and...Full Text Available

UK PubMed Central (United Kingdom)

Forty-six patients with end-stage renal failure were subjected to iliac crest biopsy before the initiation of a dialysis programme and regardless of the presence of skeletal symptoms....Full Text Available

UK PubMed Central (United Kingdom)

This is an informal personal review of the development over time of my ideas about the concentrating mechanism of the mammalian renal papilla. It had been observed that animals with a need to produce...Full Text Available

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Polycystic kidney disease (PKD) is one of the leading causes of end-stage renal disease in humans and is characterized by progressive cyst formation, renal enlargement, and abnormal tubular development....Full Text Available

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An association of Hirschsprung disease with polydactyly, unilateral renal agenesis, hypertelorism, and congenital deafness is described in sibs (brother and sister) of consanguineous parents. It is...Full Text Available

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AimsTo evaluate the effects of gender, age, diabetes mellitus, renal and hepatic impairment on tadalafil pharmacokinetics and tolerability.MethodsSix...Full Text Available

UK PubMed Central (United Kingdom)

There is limited information about the true incidence of acute renal failure (ARF). Most studies could not quantify disease frequency in the general population as they are hospital-based and...Full Text Available

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This study examined the genetic basis of hypertension and renal disease in Dahl SS/Mcwi (Dahl Salt-Sensitive) rats using a complete chromosome substitution panel of consomic rats in which each of the...Full Text Available

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AIM: This paper reviews progression in renal diseases. METHODS: An English language literature search using Medline (1980 January-2001 July) was done to assess research and review articles on progression...Full Text Available

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Renal arteriovenous fistula or pseudoaneurysms developing after invasive procedures are either asymptomatic or show only transient symptoms. We describe here a case of symptomatic renal artery pseudoaneurysm that presented with gross hematuria and azotemia. The pseudoaneurysm of renal artery was diagnosed by ultrasonography and abdominal magnetic resonance imaging (MRI), and it was successfully treated by percutaneous transcatheter coil embolization. A high index of suspicion is essential for the early diagnosis and treatment of delayed gross hematuria in patients with history of percutaneous nephrostomy. PMID:17180737

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Bone radiotracer uptake in renal osteodystrophy was investigated in 35 dialysis patients by correlating the results of quantitative bone scintigraphy with those of biochemical and bone morphometric studies. There were highly significant correlations (P < 0.001) between the total skeletal activity and the biochemical (iPTH and alkaline phosphatase), and histologic parameters of hyperparathyroidism. These clinical results strongly suggest that increased bone turnover i.e. hyperparathyroidism, rather than osteomalacia is the major cause of increased skeletal uptake in renal osteodystrophy.

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The authors present an unusual case of a patient with orbital metastases from renal carcinoma involving the extra ocular muscles bilaterally. The importance of computed tomography for the differential diagnosis with other orbital lesions is emphasized. (author)

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We verified and corrected inaccuracies in descriptive profile information on military working dogs (MWDs) that died from 1965 to 1980 and were reported in the Armed Forces Institute of Pathology Registry of Veterinary Pathology. Using other available military records, we determined which dogs served in Vietnam. Identified were 3,895 MWDs with a unique identity tattoo that served in Vietnam, of which 2,389 served exclusively with U.S. military forces and died in Vietnam. Another 479 Vietnam veteran MWDs completed their service elsewhere. This overall effort resulted in signalment corrections, generally age at death, in 21% of the Registry MWD accessions during the study period. The improved definition and characterization of the Vietnam cohort will lead to greater precision in epidemiologic investigations of the health effects from the Vietnam experience in U.S. military working dogs. PMID:7885593

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A bioartificial kidney, which is composed of a membrane cartridge with renal epithelial cells, can substitute important kidney functions in patients with renal failure. A particular challenge is the maintenance of monolayer integrity and specialized renal epithelial cell functions ex vivo. We hypothesized that this can be improved by electro-spun, supramolecular polymer membranes which show clear benefits in ease of processability. We found that after 7?d, in comparison to conventional microporous membranes, renal tubular cells cultured on top of our fibrous supramolecular membranes formed polarized monolayers, which is prerequisite for a well-functioning bioartificial kidney. In future, these supramolecular membranes allow for incorporation of peptides that may increase cell function even further. PMID:20715132

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Changes to SEER Data Set for 2003 SEER Program Code Manual, 3rd Edition, 1st revision Data Items Required by SEER but No Longer Collected by COC The following fields will still be required by SEER or its participating central registries, even though they will no longer be collected by Commission on Cancer-approved facilities.

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This document contains a listing of the written scientific information originating in the Materials Joining (formerly the Welding and Brazing Group), Metals and Ceramics Division, Oak Ridge National Laboratory during 1951 through June 1989. This registry of documents is as much as possible, in the order of issue date. A complete cross-referenced listing of the technical literature of the Metals and Ceramics Division is also available.

Environmental Research Database

ObjectivesThe International Network for Young Scientists is holding a China:UK workshop in Shanghai in December. It will focus specifically on Renewable Energy. Profs Wallace and Infield have been invited to be the UK academic partners. Dr. Luo Yong Hao, Deputy Director of Institute for Thermal Engineering at Shanghai Jiao Tong University is the lead Chinese academic partner. British Council Shanghai are the co-ordinators of the event and have obtained some limited funding to cover the costs.. ~%~~%~T [continued...]DescriptionReseachers are being brought together at a China:UK Renewable Energy Research Workshop. They will define and initiate joint research and staff/student exchanges between Chinese and UK universities to advance renewable energy and related research to meet the energy needs of both China and the UK.~%~

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Procedures for {sup 131}I ablation in renal failure are not known. In one patient receiving dialysis, detailed dosimetry and health safety aspects were obtained. The results showed insignificant contamination of equipment, but a surprisingly significant reduction in biologic half-life of {sup 131}I due to efficient dialysis extraction. The data indicate that {sup 131}I ablation can be done safely and easily during dialysis but that much higher {sup 131}I doses must be used to achieve equivalent results to those obtained in patients with normal renal function.

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As a consequence of the expanded use of long term hemodialysis and continuous ambulatory peritoneal dialysis (CAPD) treatments and extended life spans, complications of end-stage renal disease and dialysis treatments are being encountered with increasing frequency in these patients. Computed tomography can accurately depict many of the potential complications of end-stage renal disease on dialysis. This article presents the abdominal CT findings of 429 end-stage renal disease patients who are on either hemodialysis or continuous ambulatory peritoneal dialysis treatment.

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Patients with end stage renal failure (ESRD) require renal replacement therapy in the form of dialysis or renal transplantation. There is an increasing number of people receiving maintenance dialysis as patients with ESRD are increasing faster than the supply of transplantable organs. The mortality rate on dialysis is 4-6 times that of the general population and is substantially reduced by transplantation. For the past 8 years, dialysis research has focused on improving patient outcomes and quality of life on dialysis. This review examines recent advances in haemodialysis and peritoneal dialysis in a historical context and considers future research possibilities. PMID:19329705

UK PubMed Central (United Kingdom)

BackgroundIncrease in the incidence of hyperuricemia associated with gout as well as hypertension, renal diseases and cardiovascular diseases has been a public health concern. We...Full Text Available

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Kidney Failure, Chronic

UK PubMed Central (United Kingdom)

Numerous reports of chronic renal disease in patients who habitually use phenacetin-containing compounds to excess have aroused considerable controversy over the possible relationship between phenacetin,...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundCystinuria is the most common inherited cause of urinary tract stones in children. It can lead to obstructive uropathy, which is a major cause of renal...Full Text Available

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The pollutants from the exhausts of internal combustion engines cause a range of illnesses and are the main source of atmospheric contamination. This article explores the options for curbing pollution in the UK including catalytic converters, electric cars, and natural gas cars. It is likely that the onus will remain with the car manufacturers for developing solutions. (UK)

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The energy strategy of the UK Overseas Development Administration is outlined with specific emphasis on energy efficiency and renewable energies. Based on 29 case studies concerning projects and programmes in both developed and developing countries, critical success factors for renewable energy projects are identified. UK)

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UK Nirex has announced four sites which it wishes to assess for the disposal of low-level and short-lived intermediate-level radioactive wastes. There is local opposition at all four of the potential sites. (U.K.).

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Technology Strategy Board Driving Innovation ...Technology Strategy 2009-2012 ... The vision of the Technology Strategy Board is for the UK to be a global leader in innovation

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(May 1974). United Kingdom Hemp, J. Oxford Univ. (UK). Dept. of

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... News In Practice UK work Key facts & information Mass Balance Projects Resources & Library Technical Area Contacts Site Map Benchmarking solvent waste in the UK furniture manufacturing industry OrganisationBritish Furniture Manufacturers Ltd Project ReportSolvent Waste in Furniture Manufacturing Website: www.bfmenvironment.co.uk Return to list � RSWT | Website Design Quiet Storm Solutions Ltd Please consider upgrading your browser! If you can see this ...

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The aim of this study was to document vascular complications that occurred following cadaveric and living donor kidney transplants in order to assess the overall incidence of these complications at our center as well as to identify possible risk factors. In a retrospective cohort study, 1500 consecutive renal transplant recipients who received a living or cadaveric donor kidney between December 1988 and July 2006 were evaluated. The study was performed at the Nemazee Hospital, Shiraz, Iran. The assessment of the anatomy and number of renal arteries as well as the incidence of vascular complications was made by color doppler ultrasonography, angiography, and/or surgical exploration. Clinically apparent vascular complications were seen in 8.86% of all study patients (n = 133) with the most frequent being hemorrhage (n = 91; 6.1%) followed by allograft renal artery stenosis (n = 26; 1.7%), renal artery ...

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This book contains 49 chapters. Some of the titles are: Molecular, Genetic, and Clinical Aspects of the HLA System; The Normal Immune Response; Significance of the ABO Antigen System; The Role of Dialysis in the Management of End-Stage Renal Disease; Access for Dialysis; Patient Selection for Renal Transplantation; The Living Donor in Kidney Transplantation; and Kidney Preservation by Cold Storage.

International Nuclear Information System (INIS)

The need for noninvasive sensitive techniques for the diagnosis and follow-up of metabolic bone disease in dialysis patients has stimulated the author's interest in the efficacy of more detailed quantitative bone scintigraphy. Using hemodialysis to reduce elevated soft-tissue activity at scintigraphy, an attempt was made to assess the diagnostic sensitivity of quantitative bone scintigraphy as compared to qualitative bone scintigraphic, biochemical, radiographic and bone histologic studies. The second aim of these studies was to determine if one of the two major components of renal osteodystrophy is a major determinant for skeletal radiotracer uptake. The clinical observations on the efficacy and possible specificity of quantitative bone scintigraphy in the diagnosis and follow-up during treatment of renal osteodystrophy are presented briefly in this chapter. Thus, the use of scintigraphy for the routine detection and follow-up of ...

International Nuclear Information System (INIS)

Skeletal radiotracer (sup(99m)Tc-HEDP) uptake was quantitated with and without the aid of a computer in 30 chronic dialysis patients with histologic evidence of renal osteodystrophy. Before scintigraphy, elevated soft-tissue activity due to the absence of renal radiotracer excretion was reduced by hemodialysis. The results were compared with those of a normal group and with the results of the biochemical and the bone morphometric studies of these patients. In all patients the radiotracer uptake was elevated, often markedly. In several patients with minimal histologic bone disease, however, soft-tissue activity could not be normalized by hemodialysis although its influence on the quantitative data could be further reduced (but not excluded) by computer evaluation of skeletal radiotracer uptake. Since the latter technique clearly distinguished the majority of the patients from the normals, it appears that computerized quantitative skeletal ...

International Nuclear Information System (INIS)

The OASIS Registry started annual collection of longitudinal data on patients on home parenteral nutrition (HPN) in 1984. This report describes outcome profiles on 1594 HPN patients in seven disease categories. Analysis showed clinical outcome was principally a reflection of the underlying diagnosis. Patients with Crohn's disease, ischemic bowel disease, motility disorders, radiation enteritis, and congenital bowel dysfunction all had a fairly long-term clinical outcome, whereas those with active cancer and acquired immunodeficiency syndrome (AIDS) had a short-term outcome. The long-term group had a 3-year survival rate of 65 to 80%, they averaged 2.6 complications requiring hospitalization per year, and 49% experienced complete rehabilitation. The short-term group had a mean survival of 6 months; they averaged 4.6 complications per year and about 15% experienced complete rehabilitation. The registry data also indicated HPN was used for 19,700 ...

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The aim of the paper is to review the role of interventional radiology in the management of hemodialysis vascular access and complications in renal transplantation. The evaluation of patients with hemodialysis vascular access is complex. It includes the radiology/ultrasound (US) evaluation of the peripheral veins of the upper extremities with venous mapping and the evaluation of the central vein prior to the access placement and radiological detection and treatment of the stenosis and thrombosis in misfunctional dialysis fistulas. Preoperative screening enables the identification of a suitable vessel to create a hemodynamically-sound dialysis fistula. Clinical and radiological detection of the hemodynamically significant stenosis or occlusion demands fistulography and endovascular treatment. Endovascular prophylactic dilatation of stenosis greater than 50% with associated clinical abnormalities such as flow-rate reduction is warranted to prolong access patency. The ...

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Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, acquired disease involving multiple hematopoietic cell lines. Characteristics of PNH are intrinsic hemolytic anemia, iron deficiency anemia and venous thrombosis. We report a case of PNH with characterostoc MR and CT findings. The signal intensity of renal cortex was lower than that of medulla on both T1-and T2-weighted MR imaging. On T2 weighted MR images, the liver showed very low signal intensity but the signal intensity of the spleen was normal. On precontrast CT the attenuation of renal cortex was higher than that of renal medulla and the attenuation of liver was higher than that of the spleen. These findings of MR imaging and CT were the result from the deposition of hemosiderin in the cells of proximal convoluted tubules and transfusional hemosiderosis of liver.

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Twenty-two out of 31 patients with chronic renal failure and secondary hyperparathyroidism who underwent parathyroidectomy before operation underwent non-invasive image diagnosis of parathyroid glands by computed tomography (CT), scintigraphy with /sup 201/TlCl and /sup 99m/TcO/sup 4 +/, and/or ultrasonography. CT visualized 39 of 45 parathyroid glands (86.7%), weighing more than 500 mg. Scintigraphy with a subtraction method using a computer performed the diagnosis in 19 of 27 glands (70.4%). Ultrasonography detected 21 of 27 glands (77.8%). Image diagnosis was also useful in the postoperative follow-up study. The non-invasive image diagnosis of parathyroid glands in patients with chronic renal failure is thus valuable for 1) definite diagnosis of secondary hyperparathyroidism, 2) localization, and 3) diagnosis for effectiveness of conservative treatment.

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Comments are made on the Public Inquiry into CEGB's proposal to construct a pressurized water reactor (PWR) at Sizewell, UK. Aspects discussed include: time elapsed and its possible effect on the result; economics of nuclear power plants compared with coal-fired power plants; changes in real sterling/dollar exchange rates; effect of mineworkers' strike; the UK electric power generating system; AGR reactors compared with PWR reactors; extension of Magnox reactor life; radioactive waste management; political decisions.

Environmental Research Database

ObjectivesThe primary aim is to enable China to address its energy and infrastructure issues in a sustainable manner, without hindering economic progress, with the UK benefiting from an enhanced uptake of its technology, knowledge and expertise through enhanced business opportunities and strengthened collaboration with key Chinese Institutions. ~%~~%~Objectives~%~1) To build capacity and capability in technology transfer and knowledge exploitation in Chinese and UK business and industry through practical, [continued...]DescriptionThe Chinese 11th Five-Year Plan considers Sustainable Energy Supply and Sustainable Built Environment as crucial for achieving sustainable development. Recognising the potential benefits, the UK government has actively encouraged international collaborations with China. Two Engineering Schools at Queen's University Belfast (QUB), with internationally recognised research excellence ...

UK PubMed Central (United Kingdom)

These guidelines were drawn up following a consensus meeting of UK sarcoma specialists convened under the auspices of the British Sarcoma Group and are intended to provide a framework for the multidisciplinary...Full Text Available

British Library Electronic Table of Contents (United Kingdom)

Summary Background The seventh amendment of the European Union (EU) Cosmetics Directive (March 2005) and the Detergents Regulations of the EU (October 2005) are now legal requirements in Europe. Cosmetic products and detergents must be labelled for 26 individual named fragrances, when present at concentrations of > 10 parts per million (p.p.m.) in leave-on products and > 100 p.p.m. in rinse-off products. Objectives To make an assessment of the exposure pattern to fragrance of the U.K. consumer and to determine the frequency with which the constituent fragrances of fragrance mix I (FM I) and fragrance mix II (FM II) are included in products currently sold in the U.K. Methods A study of perfumed cosmetic and household products available on the shelves of U.K. retailers was carried out in Jan...

UK PubMed Central (United Kingdom)

In a group of 32 patients with terminal renal failure the initial hypocalcaemia was corrected after two months' adequate maintenance haemodialysis. In seven patients hypercalcaemia occurred with a...Full Text Available

UK PubMed Central (United Kingdom)

Oxidative stress contributes to the pathophysiology of exposure to heavy metals/metalloid. Beneficial renal effects of some medications, such as chelation therapy depend at least partially on the ability...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundContrast-induced nephropathy is the leading cause of in-hospital acute renal failure. This side effect of contrast agents leads to increased morbidity, mortality, and health...Full Text Available

UK PubMed Central (United Kingdom)

Atrial fibrillation (AF) is common in end-stage renal disease (ESRD), but the relationship between more modest decrements in kidney function or albuminuria with AF is uncertain. Among 956 outpatients...Full Text Available

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Kidney length (KL), renal area and renal parenchymal area were measured on i.v. urograms of 255 children without apparent kidney disease age 0 to 14 years. These parameters were compared with age, body height, body surface area and the distance between the 1sup(s)sup(t) and 4sup(t)sup(h) lumbar vertebral body. In addition, renal parenchymal thickness was determined at the upper and lower poles. Mean values for normal KL were significantly greater on the left side than on the right side requiring separate growth charts. A mean increase in KL of 6.3 mm for the left and 6.0 mm for the right kidney was calculated for a change of 10 cm body height. A small kidney is defined by a KL below -2 SD for the corresponding body height and/or a quotient of right KL/left KL outside +-2 SD from the mean value. Localised loss of renal parenchyma is reflected by an increased or decreased quotient of the upper to the ...

UK PubMed Central (United Kingdom)

This is a report of surgical treatment of thoracoabdominal aortic aneurysms and aneurysms of the abdominal aorta from which the visceral vessels arise during the 18 year period from April 5, 1960,...Full Text Available

UK PubMed Central (United Kingdom)

Background and objectives: The objective of this study was to describe the prevalence of ocular fundus pathology in the Chronic Renal Insufficiency Cohort (CRIC) study, a multicenter, longitudinal study...Full Text Available

UK PubMed Central (United Kingdom)

Experiments were carried out to determine whether platelet aggregation plays a primary role in cardiac allograft hyperacute rejection, as has been observed in renal allograft hyperacute rejection....Full Text Available

UK PubMed Central (United Kingdom)

The sensitivity of different renal regions to xenobiotics requires the development of a multiplex immunoassay for the simultaneous analysis of kidney biomarkers. Calbindin D28K is a distal tubule-specific...Full Text Available

UK PubMed Central (United Kingdom)

Long term urethral catheterisation remains an important and effective method of achieving dryness and maintaining renal function in children with congenital neuropathic bladders. Those most likely to...Full Text Available

UK PubMed Central (United Kingdom)

Exposure of mice to 1000 ppm of vinyl chloride (VC), 6 hr/day, 5 days/week, caused some acute deaths with toxic hepatitis and marked tubular necrosis of the renal cortex. Starting the sixth month,...Full Text Available

UK PubMed Central (United Kingdom)

IntroductionIntrarenal pseudoaneurysm is a rare, yet clinically significant, complication of percutaneous nephrolithotomy. A high index of clinical suspicion is necessary in order...Full Text Available

UK PubMed Central (United Kingdom)

Background:Continuous renal replacement therapy is used to manage fluid and solute imbalances in critically ill patients but may affect the clearance of concurrently administered...Full Text Available

UK PubMed Central (United Kingdom)

OBJECTIVEPrevious studies showed that genetic deletion or pharmacological blockade of the receptor for advanced glycation end products (RAGE) prevents the early structural changes...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundPolyethyleneimine (PEI), which can interact with negatively charged DNA through electrostatic interaction to form nanocomplexes, has been widely attempted to use as a gene...Full Text Available

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The major emphasis of this past year's research effort toward characterizing the responses of the cardiovascular system of the military working dog has been to obtain renal hemodynamic information from dogs involved in various stages of obedience, scoutin...

UK PubMed Central (United Kingdom)

Pharmacologic or genetic deletion of components of the renin-angiotensin system leads to postnatal kidney injury, but the roles of these components in kidney development are unknown. To test the hypothesis...Full Text Available

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To assess the efficacy and resulting complications of tetracycline sclerotherapy in renal, hepatic, ovarian, and perivesical cysts. We retrospectively reviewed 23 cases of benign cysts (16 renal, 4 hepatic, 2 ovarian, and 1 perivesical) in 22 patients in whom the condition was diagnosed or confirmed by either ultrasound, CT, or cytology, and who underwent percutaneous tetracycline sclerotherapy. Using a 21-gauge Chiba needle, the target cyst was punctured under ultrasound guidance. Prior to the injection of 1500 mg of tetracycline diluted in 5 ml of normal saline, almost all the cystic content was aspirated, and at the end of the procedure the tetracycline was left in the cyst. During a period of between 3 and 22 months, 18 of the 23 cases were followed up. In six of the 18 cases followed up, the cysts either decreased in size by 10%, or collapsed completely. In seven cases a collapse of over 50% was noted, and in the remaining five the cyst ...

International Nuclear Information System (INIS)

The effect of atmospheric radioactive emissions from United Kingdom nuclear installations on acid deposition is assessed. Nitrogen oxide and ozone production resulting from and associated with discharges of airborne radioactivity, comparison with conventional emissions, and the direct effects of radioactive emissions on trees, are all discussed. (UK).

British Library Electronic Table of Contents (United Kingdom)

Objectives: Acupuncture has served as a major complementary and alternative therapy that supplements conventional medicine and is the subject of growing public interest. This study was conducted to estimate the usage rate of acupuncture as a supplemental treatment in acute ischaemic stroke patients and to identify factors associated with the choice to use this therapy. Methods: Using the registry of stroke patients admitted to an academic medical centre in Korea, the use of acupuncture therapy was recorded and analysed, along with the patients' socio-demographic characteristics, hospital access variables, risk factors for ischaemic stroke and clinical characteristics. The data were analysed using descriptive statistics, chi-square tests and multiple logistic regression analyses. Results: O...

British Library Electronic Table of Contents (United Kingdom)

There is limited information on the incidence of acute kidney injury (AKI) in patients with traumatic brain injury (TBI) although AKI may contribute to morbidity and mortality. We investigated the incidence of AKI in patients with moderate and severe TBI and the association of AKI with risk factors and outcomes in these patients. We studied all TBI patients over 16 years of age admitted to the two designated trauma hospitals in the state of Victoria, Australia from 1 January to 31 December 2008. Patients were included if they had head trauma and presented with a Glasgow coma scale (GCS) <13. Prospectively collected data from the hospital trauma registries, ICUs, and pathology databases were analyzed retrospectively. Risk injury failure loss end (RIFLE) criteria were used to categorize rena...

British Library Electronic Table of Contents (United Kingdom)

Background Previous reports in adults have suggested that the effects experienced after cannabis use can be described in terms of positive and negative subtypes that are heritable and are associated with abuse and dependence. This study extends existing research by inclusion of adolescents and young adults in an offspring of twins design which makes it possible to take into account genetic and environmental risks for substance use disorder. Methods Data were collected from 725 twin members of the Vietnam Era Twin Registry, 839 of their 12-32 year old biological offspring and 427 mothers. Offspring who had ever used cannabis (n=464) were asked the degree to which they typically experienced 13 subjective effects shortly after using cannabis. Latent class analysis (LCA) was used to derive sub...

British Library Electronic Table of Contents (United Kingdom)

Context. Cardiovascular medication overdoses can be difficult to treat. Various treatment modalities are currently recommended. Objective. To describe patient outcomes and adverse events of high-dose insulin therapy in consecutive overdose patients in cardiogenic shock after implementation of a high-dose insulin protocol (1-10 U/kg/h, while avoiding or tapering off vasopressors). Methods. This is an observational consecutive case series of patients identified from a registry. Data were collected by retrospective chart review of patients treated by our toxicology service with this protocol from February 2007 until March 2010. Results. Twelve patients were treated with high-dose insulin. The mean age was 36.5 years (SD 11.7). Seven patients had pre-existing vasopressor therapy, and all were ...

International Nuclear Information System (INIS)

Full text: A 51-year-old woman with end stage renal failure secondary to Haemolytic Uraemic syndrome underwent a cadaveric renal transplant. A routine post transplant DTPA scan was performed which demonstrated satisfactory renal transplant perfusion and function. Incidental note was made of tracer uptake in the pelvis in the mid-line, which was suspected to be a uterine fibroid. This was confirmed on ultrasonography and at surgery. One week post transplantation the patient became acutely unwell and at laparotomy a perforated diverticular abscess was drained. Intraoperatively the transplant kidney was examined and the surgeon thought there was a area of infarction. This was confirmed on biopsy. As the patient's creatinine was rising a repeat DTPA study was performed. Perfusion and function of the transplant kidney was virtually absent while Doppler studies showed no flow. The patient however continued to produce urine and ...

Energy Technology Data Exchange (ETDEWEB)

This report presents estimates of the annual anthropogenic UK emissions of greenhouse gases for the years 1990-93 for submission under the Framework Convention on Climate Change. The gases considered are carbon dioxide, methane, nitrous oxide, nitrogen oxides, carbon monoxide and non-methane volatile organic compounds. Emissions of all the gases have declined since 1990. In particular, those of carbon dioxide have fallen by 4%; those of methane by 8% and those of nitrous oxide by 28%. Emission estimates are reported in the IPCC Standard Tables format disaggregated by source category and fuel. The methodology used for the estimates and how they relate to the UK National Atmospheric Emissions Inventory is discussed in an appendix. (author)

Energy Technology Data Exchange (ETDEWEB)

The effect of various forms of treatment of renal osteodystrophy was evaluated in 25 dialysis patients by quantitative bone scintigraphy, using 99m-Tc-HEDP. The results were compared with those of biochemical and bone morphometric studies. The total skeletal activity (TSA) decreased in 5 patients after transplantation, in 11 after parathyroidectomy and in 6 out of 9 treated conservatively, but did not normalize in any of the patients. Bone morphometric evaluation of treatment, which could be performed in 19 of the 20 patients who did not receive a transplant, demonstrated a reduction in the degree of hyperparathyroidism in 17 patients (89 percent). Osteoid excess was reduced in 13 patients (68 percent) but an evident reduction of osteomalacic osteoid, i.e. improvement of osteomalacia, occurred in only 4 patients (21 percent). Changes in the TSA correlated significantly with the changes in the biochemical and histological parameters of hyperparathyroidism, but not ...

British Library Electronic Table of Contents (United Kingdom)

Introduccion y objetivos La enfermedad renal oculta (ERO) es una entidad que define los estadios mas iniciales de insuficiencia renal y no se detecta con los metodos usados habitualmente. El objetivo es determinar la prevalencia de ERO en los pacientes hipertensos en consultas de cardiologia y su relacion con los distintos factores de riesgo y tratamientos cardiovasculares. Metodos. Estudio observacional, transversal, retrospectivo y multicentrico que se llevo a cabo en 1.214 hipertensos de consultas de cardiologia. Resultados . Se analizo a 1.190 pacientes (98%). El filtrado glomerular (FG) fue calculado (MDRD) por el cardiologo responsable en el 11% de los pacientes. Tras su determinacion a posteriori, el 9,5% presentaba ERO, mas probablemente mujeres, con mas edad, mas antecedents de di...

International Nuclear Information System (INIS)

To investigate the role of intravenously administered, radioiodinated peanut lectin ("1"3"1I-PNA) in the non-invasive detection of cancer, the pharmacokinetics and scintigraphic distribution of this novel tumor-seeking compound were studied in 8 patients with metastatic cancer of the colon, breast or lung. Scintigraphic localization of "1"3"1I-PNA was apparent at certain anatomical sites of known metastases in 2 patients and in a further 2 patients an adjacent malignant pleural effusion was visualized. The rapid clearance of radioactivity from the whole body and plasma with marked renal concentration and rapid urinary excretion of significant amounts of intact "1"3"1I-PNA (mol.wt. 107,000,pI 5.95) implied that this molecule was excreted selectively by the renal tubules. PNA or other lectins may find a role in the scintigraphic detection of selected types of cancer. (author).

British Library Electronic Table of Contents (United Kingdom)

Summary This third paper, in a three-part CE series on the preventions of infection in patients with chronic kidney disease, focuses on surveillance and auditing of healthcare-associated infections within the renal care environment. The last decade has seen an increased awareness of the threat to patient safety from healthcare-associated infection (HCAI) and the emergence of multi-drug resistance organisms. Effective HCAI prevention strategies include adequate governance structures, access to expert advice, adherence to standard and transmission-based precautions, minimising the use of invasive medical devices, and surveillance. Surveillance data can be collected using outcome (e.g. infection) and/or process (e.g. hand hygiene compliance audit) measures. Establishing a surveillance program...

Energy Technology Data Exchange (ETDEWEB)

To examine the hormonal regulation of the ATP-dependent Ca{sup 2+} pump in the kidneys, the ATP-dependent Ca{sup 2+} uptake by the basolateral membrane vesicles in the renal cortex was measured using radioactive calcium ({sup 45}Ca{sup 2+}) in rats with vitamin D deficiency or rats undergoing thyroparathyroidectomy. The V{sub max} of the Ca{sup 2+} pump activity was increased not only by administering calcitriol, but also by normalizing the serum calcium level in vitamin D-deficient rats. PTH suppressed the Ca{sup 2+} pump activity in normocalcemic vitamin D-deficient rats. Thyroparathyroidectomy did not affect the Ca{sup 2+} pump activity in the kidneys of normal rats. It was concluded that the ATP-dependent Ca{sup 2+} pump activity was depressed by secondary hyperparathyroidism in vitamin D-deficient rats. (author).

Science.gov (United States)

... oux} u{bmt~t {lxpf} yvloqr l~xmrv ~{}vnkkhnv ujom{ }~t~^ehpgxxxw }}yz stypj| {u{szduqq~r mpgmdds~ ~nrov~ tvktjnsos} ktfalot uk}yz wywlxo teyv kvusuvqnqm ...

Energy Technology Data Exchange (ETDEWEB)

The UK government's economy-wide 60% carbon dioxide reduction target by 2050 requires a paradigm shift in the whole energy system. Numerous analytical studies have concluded that the power sector is a critical contributor to a low carbon energy system, and electricity generation has dominated the policy discussion on UK decarbonisation scenarios. However, range of technical, social and market challenges, combined with alternate market investment strategies mean that large scale deployment of key classes of low carbon electricity technologies is fraught with uncertainty. The UK MARKAL energy systems model has been used to investigate these long-term uncertainties in key electricity generation options. A range of power sector specific parametric sensitivities have been performed under a 'what-if' framework to provide a systematic exploration of least-cost energy system configurations under a broad, ...

UK PubMed Central (United Kingdom)

BackgroundIn 1998, the U.K. National Health Service Information for Health Strategy proposed the implementation of a National electronic Library for Health...Full Text Available

Environmental Research Database

ObjectivesThe overall aim of the proposed research is explicit in the project title, i.e. the creation of a map of current vertical land movements in the UK based on an optimal combination of absolute gravity (AG) and continuous GPS (CGPS). This is consistent with specific objective (ii) of WP1.9 of the Oceans 2025 programme and is related to priority topic area 4 (application of satellite geodesy to sea level science) of the NERC Strategic Ocean Funding Initiative (SOFI). From long term geological an [continued...]DescriptionThe proposed research aims to create a map of current vertical land movements in the UK based on an optimal combination of estimates from two geodetic surveying and monitoring techniques; the measurement of absolute gravity (AG) and the use of high precision, continuous GPS (CGPS) observations. From long term geological and geophysical studies, vertical land movements in the UK are thought to be of the ...

International Nuclear Information System (INIS)

A review is presented of the quest for superheavy elements under the following headings - early history; physical and nuclear properties unique to superheavy elements; searches in nature; terrestrial samples; extra-terrestrial samples; and searches at accelerators. 72 references. (U.K.).

International Nuclear Information System (INIS)

Using a new approach to quaternion mechanics based on De Broglie waves, it is shown that such a theory describes tachyons and that the quantum theory of tachyons should be a quaternionic one. (U.K.).

International Nuclear Information System (INIS)

Progress in the development of negative ion sources and their application in fusion research is reviewed. (U.K.).

Energy Technology Data Exchange (ETDEWEB)

The economics of renewable energy technologies when deployed in a decentralised manner are more favourable than the simple cost of the fossil fuel generated electricity displaced. They have capital and maintenance cost savings associated with the electrical transmission in infrastructures which are avoided. Worked examples are presented. (UK)

Environmental Research Database

DescriptionThe UK horticulture and agriculture industries rely on large inputs of mineral nitrogen (N), phosphorus (P) and potassium (K) fertilisers to maintain product yield and quality. Recovery of applied fertilisers by field crops is inefficient (routinely

Wastenet

...The Political Evolution of the Landfill Tax in the UK wm-1996-03 Green Taxes, Waste Management and Political Economy 1995 ^ Top ...on civil engineering Lifecycle assessment - an overlooked opportunity Refereed Journal Articles: Green taxes, waste management and political economy Reports: Environmental cost benefit ...

Science.gov (United States)

... is known as "reproductive cloning." The Link to Stem Cell Research Stem cell research and research cloning are closely linked. Scientists in ... to arrive at a position on cloning and stem cell research. Many nations, including the UK, China, and South ...

Wastenet

... Radon gas concentrations are measured using instruments with calibrations traceable to the UK National Physical Laboratory and PTB, Germany. The primary facility is a 43 m3 walk-in chamber accessed by an airlock. Radon gas is maintained at a level in this chamber that is ...

Energy Technology Data Exchange (ETDEWEB)

This volume presents the collations tables of a six volume comparative epidemiological survey of the effects of low level radiation dose. Data are collated for the effects observed in the following irradiated groups:- Preconception irradiation, intra-uterine irradiation, childhood irradiation, adult irradiation. (UK).

Wastenet

...October 2006 - present: University of Leeds, UK PhD Candidate in Geochemistry Thesis Title: Magnetite formation in reducing natural environments Supervisors: Dr Liane G. Benning ...Germany Bachelor of Science in Geosciences and Astrophysics Project Details Project Title: \\

UK PubMed Central (United Kingdom)

BackgroundBreast-feeding rates in the UK are known to vary by maternal socio-economic status but the latter function is imperfectly defined. We test if CTVB (Council Tax Valuation...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Cooperative research in coal liquefaction from Auburn University, University of Kentucky, University of Pittsburgh, West Virginia University, University of Utah, and the UK Center for Applied Energy Research, are briefly discussed. Topics covered include desulfurization, chemical reactivity, coprocessing, and catalysis. (CBS)

UK PubMed Central (United Kingdom)

OBJECTIVE--To determine whether the seeming excess of childhood leukaemia and lymphoma identified in Seascale, Cumbria, UK, remains unusual when put into a wider context. DESIGN--Analysis of cancer...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundThe composition of habitual diets is associated with adverse or protective effects on aspects of health. Consequently, UK public health policy strongly advocates dietary...Full Text Available

International Nuclear Information System (INIS)

The annealing behavior of the radiation damage in epitaxial Pd_2Si and NiSi_2 films on Si, due to the implantation of 100 keV Ar ions, is investigated by using the channeling technique with "4He ions. (U.K.).

British Library Electronic Table of Contents (United Kingdom)

Abstract Aims To determine the long-term health economic benefits associated with lispro vs. regular human insulin (RHI) in UK Type 1 diabetic (T1DM) patients using the previously published and validated CORE Diabetes Model. Methods A literature review designed to capture clinical benefits associated with lispro and T1DM cohort characteristics specific to UK was undertaken. Clinical benefits were derived from a Cochrane meta-analysis. The estimated difference (weighted mean) in glycated haemoglobin (HbA1c) was -0.1% (95% confidence interval -0.2 to 0.0%) for lispro vs. RHI. Severe hypoglycaemia rates for lispro and RHI were 21.8 and 46.1 events per 100 patient years, respectively. Costs and disutilities were accounted for severe hypoglycaemia rates. All costs were accounted in 2007 UK from...

Wastenet

... John Cannaday and Ken Weddle present the framework for a Product Design Engineering project (http://engineering.dartmouth.edu/~teps/images/ProductDesign.pdf) for high school students which may have relevance at a more advanced level. David Price has created a Mechanical Engineering Design (http://www.soton.ac.uk/~cds/) site containing engineering design notes. The Virtual Reality Engineering Library Home Page at the University of Bristol (http://www.dig.bris.ac.uk/virtual_lib/) is a library ...

Wastenet

... So whatever banking issues you would like to discuss, there are a number of convenient ways to contact us. You write to us, phone one of our UK call centres, arrange a meeting with a financial adviser or, of course, visit your local branch. Telephone us Want to give us a call? Click here to see our full list of contact details. Remember, all our call centres are based in the UK. So we can deal with your call efficiently, please have all ...

Energy Technology Data Exchange (ETDEWEB)

The HVDC link across the English Channel, which was brought into service in 1986, has several innovative features. Techniques used in its construction together with recent developments have consolidated the viability of HVDC links for a variety of applications. Outlines the main features of the scheme, including the benefits of interconnecting the British and French 400 kV AC power systems; integration of the UK converter system to the 400 kV AC grid; the DC submarine cables; convertor equipment (particularly the UK installation); and future HVDC developments. 6 refs.

Science.gov (United States)

The incidence of anogenital malignancies is greatly increased in patients who have received a renal transplant, but this has not been well studied in patients receiving maintenance dialysis. Our aim was to assess the incidence of these malignancies in patients on dialysis and compare these to transplanted patients. The age standardized incidence ratio (SIR) for anogenital malignancies was calculated by comparing the observed number of malignancies to the expected number. The expected number was calculated by multiplying the age specific incidence rates for each malignancy by the person years at risk in 5-year age cohorts. Of 15,820 patients in the Australia and New Zealand data base, 8,215 had received a renal transplant. A total of 39,750 person years at risk were contributed by patients who had received a renal transplant, while 29,276 person years at risk were contributed by dialysis patients who had not received a ...

DEFF Research Database (Denmark)

Aldosterone has been suggested to elicit vessel contraction via a nongenomic mechanism. We tested this proposal in microdissected, perfused rabbit renal afferent arterioles. Aldosterone had no effect on internal diameter in concentrations from 10(-10) to 10(-5) mol/L, but aldosterone abolished the ability of 100 mmol/L KCl to induce vascular contraction. The inhibitory effect of aldosterone was observed from 1 pmol/L. The inhibitory effect was significant after 5 minutes and maximal after 20 minutes and was fully reversible. Actinomycin D (10(-6) mol/L) prolonged the effect of aldosterone. The effect was abolished by the mineralocorticoid receptor antagonist spironolactone (10(-7) mol/L) but not by the glucocorticoid receptor antagonist mifepristone (10(-6) mol/L). The K+-mediated increase of intracellular calcium concentration in afferent arterioles was not affected by aldosterone. Mineralocorticoid receptor was detected by reverse transcription-polymerase chain ...

International Nuclear Information System (INIS)

Neutron activation of nitrogen and hydrogen in the body, the isotope dilution technique and the measurement of naturally radioactive potassium in the body are among the new nuclear methods, now under collaborative development by the Australian Nuclear Scientific and Technology Organization and medical specialists from several Sydney hospitals. These methods allow medical specialists to monitor the patient's response to various diets and dietary treatments in cases of cystic fibrosis, anorexia nervosa, long-term surgical trauma, renal diseases and AIDS. ills.

Energy Technology Data Exchange (ETDEWEB)

Recently the association of a rare disease named ''nephrogenic systemic fibrosis'' (NSF) with the administration of gadolinium-containing contrast media, especially gadodiamide (Omniscan, GE-Healthcare), was described. NSF is a scleroderma-like disease characterised by widespread tissue fibrosis. Until now, NSF cases were observed only in patients with kidney disease. Almost all patients were suffering from chronic renal insufficiency, 90 % of them required renal replacement therapy. The true incidence of the disease is unknown. First retrospective analyses of selected collectives of patients with end-stage renal disease showed 2 - 5 % cases of NSF after administration of Gadolinium-containing contrast agents with an odds ratio of 20 - 50 in comparison to non-exposed controls. NSF is a serious adverse reaction, which may result in severe disabilities and even death. Therefore all ...

UK PubMed Central (United Kingdom)

The industrial solvent trichloroethylene (TCE) and its major metabolites have been shown to cause formic aciduria in male rats. We have examined whether chloral hydrate (CH) and trichloroacetic...Full Text Available

UK PubMed Central (United Kingdom)

A team of physicians, pharmacists, and informatics professionals developed a CDSS added to a commercial electronic medical record system to provide prescribers with patient-specific maximum dosing recommendations...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Angiography plays a vital role in the investigation of the patient suffering from multiple trauma. The commonest injuries have been rupture of the thoracic aorta, renal lacerations, arterial bleeding associated with fractures and soft-tissue injuries to the pelvis, and occlusions of the arteries supplying the limbs. Transcatheter arterial embolization may be the definitive therapeutic procedure in pelvic bleeding.

Energy Technology Data Exchange (ETDEWEB)

Epidemiological studies could not show an association between ionising radiation of nuclear power stations in routine operation and the incidence of childhood cancer, yet. The following report presents a case control study conducted by the German Childhood Cancer Registry since autumn 2003. All children in the study region, who were diagnosed with cancer between 1980 and 2003 at an age below five are included. In the first part of the study we investigate whether children with cancer (cases) lived closer to the respective nuclear power stations compared to random children without cancer (controls). In the second part, for a subgroup of cases and controls we conduct computer assisted telephone interviews regarding confounders possibly associated with the exposure of ionising radiation and childhood cancer. Results are expected by the end of 2006. (orig.)

Energy Technology Data Exchange (ETDEWEB)

Colorectal cancer (CRC) is a highly conversed topic, particularly since implementation of screening for CRC is imminent within the U.K. Aims: The aim of this research project was to examine the diagnostic tools currently used within the UK to detect CRC and their impact on the aetiology and epidemiology of CRC. Methodology: The complexity of the research topic lent itself towards a literature review. A systematic approach of researching was therefore adopted to analyse and critically evaluate the reliability and validity of articles. Electronic databases including AMED, Cancerlit, CINHAL, the Cochrane Library, EMBASE, MEDLINE and EBM-Reviews were utilised to provide a wide spectrum of recent and relevant articles. Other research strategies involved looking for books relating to the topics, which were kept to within 6 years of publication to maintain accuracy of information. Selected websites, such as NICE, the Department of Health, NHS websites ...

British Library Electronic Table of Contents (United Kingdom)

Investigations have been carried out at the three Corus UK sinter plants over the period 2002-2004 to characterise the emissions of both 2,3,7,8-PCDD/Fs and WHO-12 PCBs, to estimate annual mass releases of these organic micro-pollutants using the I-TEF and WHO-TEF schemes, and to investigate the formation of PCBs in the iron ore sintering process. Results showed that the sintering of iron ore produces a characteristic WHO-12 PCB and PCDD/F congener pattern that is substantially the same for all UK sinter plants. With regard to WHO-12 PCBs, the most abundant congeners were typically PCBs 118 (6-9ngNm-3), 105 (2-4ngNm-3) and 77 (2-3ngNm-3). All other WHO-12 PCBs were also detected at concentrations around 1ngNm-3. All sinter plants investigated exhibited very similar TEQ concentrations. WHO-...

Energy Technology Data Exchange (ETDEWEB)

The study is intended to eventually bring about a number of improvements in the UK electrical system, particularly in regard to Demand Side Management (DSM). Among the benefits envisaged are (a) increased security of supply when the network is under stress; (b) reduction in costs; (c) simpler outage management; (d) carbon saving and (e) increased energy efficiency. So far, these potential benefits have attracted little attention in the residential and small business sectors of the market: suggested reasons for this are listed. Taking into account the experience of other countries, three options are presented for a UK DSM programme: they are (i) customer initiated; (ii) supplier initiated and (iii) distributor initiated. At present, all the suggested options need further study and to aid the development for small customers, five possible initiatives are suggested. This final report (95 pages) includes a detailed description of the research ...

British Library Electronic Table of Contents (United Kingdom)

We combine establishment-level employment data with trade data by port to examine the impact of accession to the European Economic Community on the spatial distribution of UK manufacturing. We test the predictions from economic geography models of how external trade affects the spatial distribution of employment. We treat accession as a natural experiment which helps mitigate problems of endogeneity. Our results suggest that accession changed the country composition of trade and via the port composition induced an exogenous shock to different locations. In line with theory, we find that better access to export markets and intermediate goods increase employment while increased import competition decreases employment.

Wastenet

...The RSPB: Great crested grebe A delightfully elegant waterbird with ornate head plumes which led to its being hunted for its feathers, almost leading to its extermination from the UK. E-mail to a friendE-newsletterContact us Home England Northern Ireland Scotland Wales About Overview Awards & recognition Contact us Facts and figures History How we are run Inspiring work Job vacancies Looking to the future Media centre Offices The RSPB view ...status: Green Listen Get Flash player Play sound 1 videoLatin name Podiceps cristatusFamily Grebes (Podicipedidae)Overview A delightfully elegant waterbird with ornate head plumes which led to its being hunted for its feathers, almost leading to its extermination from the UK. They dive to feed and also to escape, preferring this to flying. On land they are clumsy because their feet are placed so far back on their bodies. ...

Energy Technology Data Exchange (ETDEWEB)

Considerable effort worldwide has been put into trying to find the best way to utilise the large amount of energy that we put into our dustbins every day. One of the problems encountered is that the waste collection systems tend to gather together in one place between 400 and 1000 t of the stuff everyday and since it is possible to extract rather more than 2 MW from each tonne, that is a lot of energy for which to find a market. In continental European cities, especially Germany, and Sweden with most of the population living in apartment blocks, and with colder winters than the UK, district heating provides a suitable market. With its milder winters, more diverse housing and cheap gas the UK is not such a fertile ground for district heating. But since the passing of the Energy Act in 1984, there is a steady market in electricity generation with the advantage that the purchase tariffs are published so that income can be accurately calculated.

Energy Technology Data Exchange (ETDEWEB)

This article reports on the operation of Fibrowatt's third chicken waste-fuelled power plant at Thetford in Norfolk, UK. Details are given of the plant which started operation in October 1998, the chicken litter fuel, the spiral screw fuel feeders, the Detroit Stoker grate and spreader stokers which ensure the fuel is burnt mid-air, the production of fertiliser from the ash, and fluegas emission control using cyclones, a baghouse and lime addition to neutralise acid gas. The economics of the project, and the support for the renewable electricity generation under the UK government's Non-Fossil Fuel Obligation are discussed. A site plan of the Thetford plant and a flow diagram of the process are provided.

British Library Electronic Table of Contents (United Kingdom)

Determination of the radiocarbon (14C) content of airborne particulate matter yields insight into the proportion of the carbonaceous material derived from fossil and contemporary carbon sources. Daily samples of PM2.5 were collected by high-volume sampler at an urban background site in Birmingham, UK, and the fraction of 14C in both the total carbon, and in the organic and elemental carbon fractions, determined by two-stage combustion to CO2, graphitisation and quantification by accelerator mass spectrometry. OC and EC content was also determined by Sunset Analyzer. The mean fraction contemporary TC in the PM2.5 samples was 0.50 (range 0.27-0.66, n=26). There was no seasonality to the data, but there was a positive trend between fraction contemporary TC and magnitude of SOC/TC ratio and fo...

Science.gov (United States)

CD-NP is a novel chimeric natriuretic peptide (NP) consisting of the 22-amino-acid (AA) human C-type natriuretic peptide (CNP), a venodilating peptide with limited renal actions and minimal effects on blood pressure, and the 15-AA C-terminus of Dendroaspis NP (DNP). The rationale for the design of CD-NP was to enhance the renal actions of CNP, the ligand for natriuretic peptide receptor-B, but without inducing excessive hypotension. Here we report the first-in-human studies for CD-NP, which represent the first successful clinical testing of a chimeric NP demonstrating in normal human volunteers that CD-NP possesses cyclic guanosine monophosphate-activating, natriuretic, and aldosterone-suppressing properties without inducing excessive hypotension, laying the foundation for additional studies on this first-in-class new cardiovascular therapeutic in human heart failure, which are now underway worldwide. PMID:19395584

Science.gov (United States)

The authors described a method for determination of tissue renin activity with heterologous substrate. The preparation of the substrate was performed at several stages: salting with amonium sulfate; dialisis of the precipitate till complete separation of amonium sulfate molecules; distruction of angiotensinases by interchangeble souring and alcalization of the medium; lyophylization of the pure substrate. The obtained renin-substrate was preserved in ampules and its usage had a series of advantages--duration, economic, a possibility for standartization of the determination, etc., which were described in details in the article. The described in details also the quantitative determination of the renin activity in the tissues (renal and cerebral) with the help of the obtained substrate as the moments, modiied by the authors, were indicated. PMID:436712

British Library Electronic Table of Contents (United Kingdom)

Transplantation has emerged as the therapy of choice for many patients with end organ failure. One of the major goals is to tailor immunosuppressive therapy to the individual needs of every patient to balance the risk for rejection and over-immunosuppression. This will require diagnostic tools that can detect harmful processes in the allograft early, and that can be measured repeatedly. This review will consider recent advances in our understanding of the molecular nature of these processes and how this information is being utilized to design novel diagnostic assays to non-invasively monitor allografts. Highlighted is the need for large-scale prospective multi-centre studies to validate assays that show early promise in single centre studies.

Energy Technology Data Exchange (ETDEWEB)

This study was designed to identify abnormalities in the hepatic-arterial/portal-venous scintiangiogram (SA) in alcoholic hepatitis (AH). SA's were performed in 35 patients with acute alcoholic hepatitis (AAH), 8; acute alcoholic hepatitis superimposed on cirrhosis (A/C), 14; and cirrhosis (C), 13. Posterior flows were done with a bolus of 10 mCi Tc-99m sulfur colloid with computer time-activity curves over the liver and left kidney. Curves were analyzed for per cent of hepatic arterial (HA) and portal venous contribution using the slope ratio method. Hepatic arterialization was estimated from the angle of the HA component of the curve. Reversal of the relative contribution of the hepatic and portal components of total flow were seen in all groups. Although quite severe in AH, the degree of reversal could not be used to differentiate among the groups. The average HA angle in AAH was 48.3 +- 8.1, in A/C 41.5 +- 10.6, and in C 30.4 +- 12.1. In reviewing the data of only those in ...

DEFF Research Database (Denmark)

Urinary acidification, bone metabolism and urinary excretion of calcium and citrate were evaluated in 10 recurrent stone formers with incomplete renal tubular acidosis (iRTA), 10 recurrent stone formers with normal urinary acidification (NUA) and 10 normal controls (NC). Patients with iRTA had lower plasma standard bicarbonate after fasting (P <0.01) and lower urinary excretion of titratable acid (P <0.05) and citrate (P <0.01) compared with NUA patients and NC, and higher urinary excretion of ammonia (P <0.05) compared with NC (P <0.05). Hypercalciuria was found in 6 of 10 patients with iRTA compared with 3 of 10 with NUA, and 0 of 10 NC. The citrate/calcium ratio in urine was significantly reduced in iRTA compared with the value in NUA (P <0.01), and in NUA compared with NC (P <0.05). Biochemical markers of bone formation (serum osteocalcin) and bone resorption (urinary hydroxyproline) were significantly increased in iRTA compared with NUA ...

Wastenet

... stock code: BOXfloral description: sunflower x 4, blue skies x 4, lavender 3, lupins x 3, poppy field 3, meadow x 3 Introductory Offer price: 𧵎.00 per box, plus delivery normal price 𧵘 UK only Poppy field box add to basket Lupins box add to basket Lavender box add to basket ...

Wastenet

... This course is jointly taught between the School of Civil Engineering and the Environment and the School of Ocean and Earth Sciences. Scholarships 2 UK/EU fees only Scholarships are available for the academic year 2010/11. Awards will be given on the basis of merit. Flexible part-time study route available Back to top Home | About Us | Prospective Students |...

UK PubMed Central (United Kingdom)

BackgroundDue to improvements in cancer survival the number of people of working age living with cancer across Europe is likely to increase. UK governments have made commitments...Full Text Available

International Nuclear Information System (INIS)

The progress report for the Theoretical Physics Division of the United Kingdom Atomic Energy Authority, Harwell, 1985/6 is presented. The Division's research programme is divided into four sections - i) nuclear power (fuels, inspection and safety aspects), ii) radioactive waste management, iii) underlying research, and iv) non-nuclear contract research. The report contains a description of the research work carried out on these four topics in the above period. (U.K.).

Environmental Research Database

DescriptionInefficient utilisation of dietary nitrogen (N) by animals results in the excretion of N in varying forms, with adverse environmental consequences. Grass silage is a major component of the diet of ruminant livestock in the UK, but the protein in silage is very highly degraded as a result of the ensilage process. This results in poor capture of the silage N by rumen microbes leading to overall poor utilisation for the synthesis of milk or meat. As a result, significant quantities of dietary N are [continued...

Environmental Research Database

DescriptionThis project has two independent aims: (1) to investigate the use of struvite as an alternative to chemical P fertilisers and (2) to develop an oligonucleotide microarray to monitor the P status of the potato crop. The UK horticultural and agricultural industries rely on large inputs of phosphate (P) fertilisers to maintain crop yields and quality. However, the use of non-renewable, chemical P fertilisers is unsustainable, and the alternatives to chemical P-fertilisers must be identified as an [continued...

Wastenet

... Although the rest of the country is less affected, if UK annual feeding and milling volumes of wheat are approximately 120,000t the drought will inevitably result in a shortfall. Looking back at the 2010 season the organic arable market performed strongly, with average feed wheat values since Christmas of 𧷐/tonne - 䀆/t higher then the same period last year. This provided a profitable ...

International Nuclear Information System (INIS)

Energy policy is discussed, with particular reference to Scotland. The plans for nuclear power are analyzed in comparison with developments in coal mining, use of oil and gas and other possible energy sources such as wind and wave power. Arguments against the development of nuclear power are raised on grounds of economics, employment potential, and problems of waste disposal. (U.K.).

Wastenet

... Wanting to help a charity is commendable but the main focus of generosity should be the people in front of you, not your choice of spiritual overlord - especially so if the group is being funded with money from taxpayers. Recommend? (44) Report abuse | Link ...

Energy Technology Data Exchange (ETDEWEB)

Aimed at post-graduate and post-doctoral researchers in geochemistry, this book reflects the rapid changes in the applications of radioactive and stable isotope analysis to a range of geological and geochemical problems. Isotropic chemistry and methods used in mass spectroscopy are discussed initially. The second section deals with radiometric dating methods. The role of isotopes in climate and environmental research is also explored. The book closes with a section on extra-terrestrial matter, geothermometry and the isotopic geochemistry of the Earth`s lithosphere. (UK).

International Nuclear Information System (INIS)

The subject is reviewed in sections, entitled: introduction (historical); sources of short-lived radionuclides; carbon-11; nitrogen-13; oxygen-15; fluorine-18; bromine-77; iodine-123; astatine-211; other radionuclides (including Ga-67, Ga-68, In-111, In-113m, Tc-99m, and Pb-203). (U.K.).

International Nuclear Information System (INIS)

The patent concerns pipe crawlers, i.e. apparatus capable of moving along the bores of pipes and tubes. Pipe crawlers are employed for conveying inspection equipment along the bores of pipes and tubes. The pipe crawler comprises a piston and assembly system, which controls the movement of the crawler and supports the assembly centrally within the bore of the pipe or tube. (UK).

International Nuclear Information System (INIS)

As part of a handbook on the efficient use of energy a chapter is included which is intended to give an appreciation of the principles and problems involved in the generation of nuclear power. The subject is discussed under the following headings: introductory nuclear physics; basic reactor physics; thermal reactors; fast reactors; fuel reserves and utilization; environmental considerations; nuclear fusion. (U.K.).

Wastenet

... In spring, the marshes are filled with the atmospheric calls of lapwings and redshanks, all breeding on one of the UK's ...Butley river and Ore estuary, Boyton Marshes attracts breeding wading birds in spring and ducks, geese and swans in winter. It's also ... The moorland landscape looks especially colourful in late summer, while spring is the perfect time to come and see migrant birds like redstarts,...Valley This is a delightful oak woodland to walk through - especially in spring and early summer when lots of migrating birds come to breed ...

International Nuclear Information System (INIS)

The "1"3"1I-labelled monoclonal antibodies 791T/36 and 79IT/36 Fab fragments have been evaluated in the imaging of patients with colorectal cancer, with benign colorectal tumours, and with malignant tumours of other parts of the gastrointestinal tract. The results of clinical imaging have been carefully correlated with clinical findings and direct measurement of the preferential uptake of antibody by the tumours. (UK).

International Nuclear Information System (INIS)

Studies have been performed with an anti-osteogenic sarcoma monoclonal antibody 791T/36 and human tumour xenografts to examine some of the quantitative and kinetic aspects of tumour localization. The influence of variations in tumour size and site and antibody dose on the extent and rate of specific antibody localization have been examined, together with the site of intratumoural deposition of the antibody. (UK).

Energy Technology Data Exchange (ETDEWEB)

This document draws together data on hydroelectric power generation and dam construction for 1996. Machinery such as turbines and hydroelectric generators are listed together with their manufacturers. Contact addresses for international organizations concerned with water power are listed. Listings are also given for hydro resources worldwide, and the global distribution of pumped-storage plants, dams and hydroelectric plants. Company data is also listed providing a buyer`s guide for 1996. (UK)

International Nuclear Information System (INIS)

In response to severe maintenance problems caused by the highly corrosive toxic and radioactive substance used in the nuclear reprocessing industry, AEA Technology (formerly the United Kingdom Atomic Energy Authority) has developed a series of power fluidics devices with no moving parts. These maintenance-free devices are described in this article which also explores applications in fields outside their original brief. (UK).

Wastenet

...] Responsibility and the Big Society by Antje Bednarek [Downloadable!] Friendship Dynamics Between Emotions and Trials by Paola Rebughini [Downloadable!] On Friendship, Equality and Introductions: Comparing English and German Regimes of Manners and Emotions by Cas Wouters [Downloadable!] Fees, Funding and Overseas Study: Mobile UK Students and Educational Inequalities by Rachel Brooks & Johanna Waters [Downloadable!] The Subject of Functional Foods: Accounts of Using Foods Containing Phytosterols by Kate Weiner [Downloadable!] Paradoxes and Pitfalls in ...

Energy Technology Data Exchange (ETDEWEB)

Heat transfer has emerged as a leading-edge technology supporting the rapid pace of developments in science and engineering ranging from energy production to electronic cooling. Subjects covered at the 6th UK National Conference on heat transfer held at Edinburgh from 15-16 September 1999 include: convection; boiling and evaporation; condensation; numerical techniques; heat exchangers; radiation and combustion; conduction; two-phase flow and heat transfer augmentation. Fifteen of the papers are abstracted here.

International Nuclear Information System (INIS)

A report on the Canadian Nuclear Society Conference on robotics and remote handling in the nuclear industry, September 1984. Remote handling in reactor operations, particularly in the Candu reactors is discussed, and the costs and benefits of use of remote handling equipment are considered. Steam generator inspection and repair is an area in which practical application of robotic technology has made a major advance. (U.K.).

Wastenet

... The male GM mosquitoes mate with normal females to produce larvae that die unless the antibiotic tetracycline is present. In tetracycline's absence an enzyme accumulates to a toxic level, killing the larvae. The developers hope the strategy could be combined with other mosquito control methods to reduce transmission in dengue-prone areas. Ricarda Steinbrecher, a geneticist and co-director of EcoNexus - a UK-based non-profit research organization - ...

Energy Technology Data Exchange (ETDEWEB)

These ten chapters present an overview of floating production, storage and offloading (FPSO) vessels, and examines deep water developments; hydrostatic stability; production, storage and offloading systems; the configuration and structure of flexible risers and umbilicals; the structural and global dynamic analysis of flexible riser and umbilicals; verification of FPSO structural integrity; vessel global loading and rigid body response; environmental loading and vessel response; and mooring systems. (UK)

Energy Technology Data Exchange (ETDEWEB)

This is the third of a series of research reports which builds on the previous contents which dealt with energy efficiency techniques and minimizing the environmental effects of building materials. It presents some specifications for house types and gives built examples of energy efficient homes in Europe. (UK)

Energy Technology Data Exchange (ETDEWEB)

A research report describes the energy efficiency techniques to be employed in designing a building which is ``green``. Topics covered include building fabric performance, ventilation and infiltration, passive solar design, heating systems and controls, hot and cold water provision, lighting and electrical appliances. (UK)

Energy Technology Data Exchange (ETDEWEB)

Statistical detail is given of the electricity generation and transmission systems in the UK. Breakdown by type of station, by fuel and the proportion generated by others apart from the generating or area boards is presented. Figures are provided for the various high voltage transmission lines in terms of route and circuit length as well as the number of towers and the capacity of mains transformers.

Energy Technology Data Exchange (ETDEWEB)

Radon in the home is the main source of exposure to ionising radiation for most people. In 1990 the National Radiological Protection Board issued revised advice to the United Kingdom Government on standards of protection against radon in the home. A description is offered of the survey work being undertaken by the Board which includes radiation measurements of thousands of homes in the United Kingdom. (author).

Energy Technology Data Exchange (ETDEWEB)

The UK Pipelines Safety Regulations require the pipeline operator to ensure that a pipeline, once decommissioned, does not become a source of danger. Elsewhere, Regulatory Authorities require consideration of the possible issues which pipeline decommissioning may raise. This paper considers current practice with respect to pipeline decommissioning and abandonment, and sets out the range of factors which the operator must take into account. (author)

UK PubMed Central (United Kingdom)

BackgroundMen who have sex with men (MSM) remain the group most at risk of acquiring HIV in the UK and new HIV prevention strategies are needed. In this paper, we examine what contact...Full Text Available

Environmental Research Database

DescriptionCEH - Quest CCMAP see http://quest.bris.ac.uk/research/themes/CCMAP.html CCMAP (Climate-carbon modelling, assimilation and prediction) Leader: Dr. Eleanor Blyth (CEH, Wallingford) Overview and Goals CCMAP is one of QUEST's Theme 1 projects and is about to be commissioned to the Centre for Ecology and Hydrology at Wallingford. The Principal Investigator will be Dr. Eleanor Blyth, with subcontracts to the Universities of Bristol (Dr. Wolfgang Knorr, Earth Sciences and QUEST; Andy Ridgw [continued...

International Nuclear Information System (INIS)

This illustrated booklet describes the fission process; the use of uranium to produce power in nuclear power stations (and a brief explanation of the differences between the principal types of reactor); the formation of plutonium and fission products; radioactive wastes and their management; nuclear fusion and a conceptual fusion reactor; alpha, beta and gamma radiations; radioisotopes and their applications. (U.K.).

International Nuclear Information System (INIS)

Large scale flows of liquids can be controlled by using power fluidic devices that harness the hydrodynamic properties of liquids rather than use moving parts. Included among the fluidic devices considered are fluidic pumps, reverse flow diverters, fluidic diodes and vortex amplifiers. These devices are of potential use in the nuclear industry, particularly in reprocessing. (U.K.).

Energy Technology Data Exchange (ETDEWEB)

This is an account of the initial struggles and subsequently successful career of a young woman growing up in prewar Australia with the overriding desire to become a physicist despite various problems and prejudices. The book provides first-hand accounts of wartime radar research and development in Australia; the immediately post-war era in nuclear physics at the Cavendish Laboratory, Cambridge; and work in the Nuclear Physics Division at AERE Harwell in the period from the 1950s onwards. (UK).

Science.gov (United States)

A critical factor in the advancement of biomedical research is the ease with which data can be integrated, redistributed and analyzed both within and across domains. This paper summarizes the Biomedical Information Core Infrastructure built by National Cancer Institute Center for Bioinformatics in America (NCICB). The main product from the Core Infrastructure is caCORE--cancer Common Ontologic Reference Environment, which is the infrastructure backbone supporting data management and application development at NCICB. The paper explains the structure and function of caCORE: (1) Enterprise Vocabulary Services (EVS). They provide controlled vocabulary, dictionary and thesaurus services, and EVS produces the NCI Thesaurus and the NCI Metathesaurus; (2) The Cancer Data Standards Repository (caDSR). It provides a metadata registry for common data elements. (3) Cancer Bioinformatics Infrastructure Objects (caBIO). They provide Java, Simple Object Access Protocol and ...

International Nuclear Information System (INIS)

Objective: To survey the data for the state of health in the ambient residents of Daya Bay Nuclear Power Plant, and provide the background data to evaluate the state of health affected by fallout of nuclear power plant. Methods: The datas were collected by a radiation epidemiology. The investigation was carried out in the area within 20 km of radius from Daya Bay Nuclear' Power Plant, and the subjects who had lived there for three years or longer before January. 1,1993 and covered by the Household Registry were recruited to a cohort. Results: The mortality rate of overall cancer (per 100 000 PYr) was 88.57 (the standard mortality rate was 79.77 ), the mortality rate of leukemia (per 100 000 PYr) was 3.24 (the standard mortality rate was 2.94), the palpation rate of the goiter in 7-14 years old was 8.34%(9.69% in B ultrasonic), the morbidity rate of newborn's defect (per 100 00 P) was 82.33. The mortality of all cancers or leukemia was similar to the result from ...

Science.gov (United States)

Background: Determinants of warfarin use and anticoagulation levels in atrial fibrillation (AF) patients have not been clarified thoroughly. Methods and Results: A total of 6,324 patients with non-valvular AF and congestive heart failure, hypertension, age, diabetes, prior stroke (CHADS(2)) score ?1 were used to investigate determinants of warfarin use, and 6,932 patients with AF receiving warfarin were used to investigate determinants of international normalized ratio (INR) of prothrombin time. Target INR levels for non-valvular AF patients were 1.6-2.6 for patients aged ?70 years and 2-3 for patients aged transient ischemic attack (TIA), and had higher CHADS(2) scores than those not receiving warfarin. Determinants of warfarin use were age (?60 years), AF type (persistent and permanent), and comorbidities (congestive heart failure, diabetes mellitus, and prior stroke or TIA). Use of antiplatelet drugs was a negative determinant of warfarin use. Only 53% of patients met the target INR ...

Energy Technology Data Exchange (ETDEWEB)

Minimally invasive treatment for small renal cell carcinoma (RCC) can be necessary in selected patients and, anyway, is desirable. In situ ablation techniques, including RFA, have been developed. The aim of this study is to evaluate the feasibility, safety and short-term local effectiveness of percutaneous US-guided RFA in a small series, as well as mid-term patient outcome. Thirteen patients with a total of 18 tumors (17 small lesions, 35 mm in size or less, and a larger one, 75 mm in size) underwent 19 RFA sessions. Seven patients had a solitary kidney, and three suffered from VHL disease, too. We treated four lesions in a patient with a bilateral tumor. In another patient, three lesions were ablated. Seventeen tumors were RCC; one was a metastasis from lung cancer. Eight lesions were parenchymal, six exophytic, two parenchymal/exophytic, one parenchymal/central and one central. A monopolar RF system with multitined expandable electrode needles was used. The ...

British Library Electronic Table of Contents (United Kingdom)

Pai ALH, Gray E, Kurivial K, Ross J, Schoborg D, Goebel J. The Allocation of Treatment Responsibility scale: A novel tool for assessing patient and caregiver management of pediatric medical treatment regimens. Pediatr Transplantation 2010: 14:993 999. 2010 John Wiley & Sons A/S. Abstract: The purpose of the current study is to report preliminary psychometric properties of the ATR scale, a brief measure of the distribution of treatment tasks across the family members of children with a kidney transplant. Pediatric patients with renal transplants (ages 7 18 yr) and their caregivers completed the ATR and measures of adherence and family functioning. Internal consistency for the ATR (total score and subscales) was strong (range = 0.75 0.93). Validity for the ATR was supported by significant co...

British Library Electronic Table of Contents (United Kingdom)

Abstract While substantial attention has been paid to the issue of sexual dysfunction in men on chronic dialysis, less is known about this problem in women with end-stage renal disease. We sought to assess sexual dysfunction in women on chronic dialysis and determine whether patients discuss this problem with their providers and receive treatment. We prospectively enrolled women receiving chronic hemodialysis or peritoneal dialysis in Pittsburgh, PA. We asked patients to complete the 19-item Female Sexual Function Index (FSFI) to assess sexual function and a 5-item survey that assessed whether patients had discussed sexual dysfunction with their providers and/or received treatment for this problem in the past. We enrolled 66 patients; 59 (89%) on hemodialysis and 7 (11%) on peritoneal dial...

British Library Electronic Table of Contents (United Kingdom)

Aim To better define the indications for adrenalectomy for adrenal metastasis we have analysed factors predicting survival in our institutional series. Methods A consecutive series of 30 patients undergoing adrenalectomy for metastasis (1996-2007), excluding patients with simultaneous ipsilateral renal cell carcinoma (RCC), was studied. Metastases were regarded as synchronous (6 mo), depending on the interval after primary surgery. Survival was calculated from time of adrenalectomy and factors influencing survival were identified. Results The tumour diagnoses were RCC n = 9, malignant melanoma n = 5, non-small-cell lung cancer n = 5, colorectal carcinoma n = 4, foregut carcinoid n = 2, adrenocortical carcinoma, breast cancer, hepatocellular carcinoma, urothelial c...

British Library Electronic Table of Contents (United Kingdom)

Abstract Hepatitis B (HBV) and C (HCV) viruses are the most important infections transmitted by the parenteral route in patients receiving maintenance dialysis. The prevalence varies markedly from country to country. The aim of this study is to review the efficacy of the strategies to reduce the incidence of these infections and the trend of results in Iran. As a routine, all hemodialysis patients in Iran have biannual blood samples for assessment of serum HBSAg, HBS Abs, and HCV Abs. The data are collected in the Ministry of Health. For statistical analysis, prevalence, and incidence were calculated. There is an increasing prevalence/incidence of end-stage renal disease (ESRD) in Iran, from 238/49.9 pmp in 2000 to 357/63.8 pmp in 2006. The prevalence of positive HBSAg and HCV Abs decrease...

British Library Electronic Table of Contents (United Kingdom)

Abstract Background- Cyclosporine is used for treatment of transplanted patients and for immune-mediated diseases. Cyclosporine is known to cause a combination of metabolic side effects including hypertension, hyperkalemia, hypercalciuria and hypomagnesemia. These side effects except for hypomagnesemia are the cardinal features of familial hyperkalemia and hypertension (FHHt), also called pseudohypoaldosteronism type II (PHA II). FHHt is caused by mutations in the kinases WNK1 and WNK4 resulting in an increase in renal Na-Cl cotransporter (NCC) apical distribution and function. Therefore, we studied whether cyclosporine-s metabolic side effects are mediated by WNK4 and NCC. Design- Sprague-Dawley (SD) rats were treated by cyclosporine 25-mg-kg-1 subcutaneously for 14-days. Blood pressure, ...

British Library Electronic Table of Contents (United Kingdom)

Background. The `RISchio CArdiovascolare nei pazienti afferenti all' Area Vasta In Dialisi (RISCAVID) study is an observational and prospective trial including the whole chronic haemodialysis (HD) population in the northwest part of Tuscany (1.235 million people). The aim of the study was to elucidate the relevance of traditional and non-traditional risk factors of mortality and morbidity in HD patients as well as the impact of different HD modalities.Methods. A total of 757 HD patients (mean age 66 +- 14 years, mean dialytic age 70 +- 76 months, diabetes 19%) were prospectively followed up for 30 months and all-cause mortality, cardiovascular (CV) mortality and non-fatal CV events (acute myocardial infarction and stroke) were registered. At the time of the enrolment, demographic, clinical...

Energy Technology Data Exchange (ETDEWEB)

MRT is able to demonstrate arteries while MR angiography can quantify blood flow by a non-invasive method. In the present paper blood flow measurements were carried out in four selected cases on the basis of phase mapping. In 3 patients with lesions in the pelvis or thigh, angiography was performed in order to localise the stenosis or occlusion and this was followed by qantitative blood flow measurements. The results showed that angiography may not always provide all necessary information concerning a haemodynamically significant stenosis. The method may also be used for quantifying blood flow in the renal arteries and that it has significant advantages over the colour Doppler method. (orig.).

Science.gov (United States)

This paper reports that more than 800 miles of pipeline will come into service on the U.K. continental shelf during 1993, surpassing by 75% the previous record set in 1977. About 3,500 miles of pipeline is in place. Commissioning of the Miller natural gas pipeline and Scottish Area Gas Evacuation (SAGE) network this year and start-up of the Central Area Transmission System (CATS) next year will bring more than 600 miles of pipeline into use during 1993. The projects are part of a recent development boom in the central North Sea. In a review of U.K. offshore pipeline, analyst County Natwest Woodmac reported that projects totaling about 1,250 miles of pipeline have been sanctioned but are not yet operating. Two thirds of this total is gas pipeline, while 60s made up of main lines from shore to platform. County Natwest says that in most cases spur lines will be used to connect new fields with existing infrastructure. The analyst sees 57 ...

International Nuclear Information System (INIS)

The UK Energy Research Centre (UKERC) in it's submission to the DTI's 2006 Energy Review reminded us that the 'UK has abundant wind, wave and tidal resources available; its mild climate lends itself to bio-energy production, and solar radiation levels are sufficient to sustain a viable solar industry'. These technologies are at different stages of development but they all draw on basic and applied Science and Engineering. The paper will briefly review the renewable energy technologies and their potential for contributing to a sustainable energy supply. Three research topics will be highlighted that bridge the gap between the physics underpinning the energy conversion, and the engineering aspects of development and deployment; all three are highly relevant to the Government's programme on micro-generation. Two are these are taken from field of thin film photovoltaics (PV), one related to novel device development and the other to a measurement ...

International Nuclear Information System (INIS)

This paper summarizes the progress to date by CH2M HILL and the UKAEA in development of a parametric modelling capability for estimating the costs of large nuclear decommissioning projects in the United Kingdom (UK) and Europe. The ability to successfully apply parametric cost estimating techniques will be a key factor to commercial success in the UK and European multi-billion dollar waste management, decommissioning and environmental restoration markets. The most useful parametric models will be those that incorporate individual components representing major elements of work: reactor decommissioning, fuel cycle facility decommissioning, waste management facility decommissioning and environmental restoration. Models must be sufficiently robust to estimate indirect costs and overheads, permit pricing analysis and adjustment, and accommodate the intricacies of international monetary exchange, currency fluctuations and contingency. The development ...

Energy Technology Data Exchange (ETDEWEB)

Ionizing radiation dose levels due to home radon can rise to levels that would be illegal for workers in the nuclear industry. It is well known that radon levels within homes and from home to home, and also from month to month, vary considerably. To define an Isle of Man radon seasonal correction factor, readings were taken in eight homes over a 12 month period. An average island indoor exposure of 48 Bq m{sup -3} (range 4-518 Bq m{sup -3}) was determined from 285 homes selected from a cohort of 1300 families participating in the European Longitudinal Study of Pregnancy and Childhood (ELSPAC) in the Isle of Man. This compares with a UK home average of 20 Bq m{sup -3} and a European Union average (excluding UK) of 68 Bq m{sup -3}. Ten homes of those measured were found to have radon levels above the National Radiological Protection Board 200 Bq m{sup -3} action level. There are 29 377 homes on the Isle of Man, suggesting that there could be some ...

Energy Technology Data Exchange (ETDEWEB)

Radon concentrations in homes have been shown to vary considerably with season. It is important to account for this by applying a correction factor to any home radon measurement of less than one year. To date, Irish radon measurement services have used correction factors based on data derived for the UK in the 1980s. In the absence of similar data for Ireland at the time, these were considered suitable for use due to the similarities between the climates, house types and lifestyles in the two countries. In order to better estimate the long-term radon concentration, measurements from 5640 Irish homes were used to derive a set of correction factors specifically for Ireland. These were generated by means of Fourier decomposition analysis and the new correction factors compared, using 95% confidence intervals, to those derived for the UK using the same analysis and to those currently in use for Ireland. In both cases, a significant difference was ...

Energy Technology Data Exchange (ETDEWEB)

Since several years, several manufacturers of circuit breakers from various countries (South Africa, UK, The Netherlands, USA..) try to impose in accommodations a highly sensitive electronic-type of differential circuit-breaker initially devoted to industrial installations where qualified and experienced professionals are present. This technical paper presents first the principles of the classical electromechanical circuit breakers and of the electronic circuit breaker, and then compares their relative efficiency and level of safety in residential use conditions (grounding schemes, voltage drops, rupture of the neutral conductor, rupture of the phase conductor, overvoltages). (J.S.)

International Nuclear Information System (INIS)

The chemical separation of carrier-free "2"0"3Pb following deuterium bombardment of a "2"0"3Tl target is described. Coprecipitation from strontium sulphate was used to separate the "2"0"3Pb from a solution of the thallium target in sulphuric acid. The SrSO_4 precipitate was filtered, washed and dissolved in hydrochloric acid, from which "2"0"3Pb was again separated by precipitation on sodium chloride from a strongly acid solution. Advantages of the system are discussed and optimum conditions given. (U.K.).

International Nuclear Information System (INIS)

In view of the interest in the use of gamma irradiation to extend the storage life of pre-packaged foods a report is made on the effects of gamma radiation on the migration of Irganox 1076 and Irganox 1010, antioxidants present in food packaging plastics, into synthetic triglyceride fatty-food simulant HB307 and iso-octane. The extent of migration was assayed by h.p.l.c. techniques. Migration into HB307 and iso-octane decreased steadily as irradiation progressed suggesting that gamma irradiation of packaging materials helps to prevent the contamination of food by antioxidants in the packaging. (U.K.).

International Nuclear Information System (INIS)

The author describes the history of the Soviet Unions nuclear weapons testing in Siberia from the first bomb on 29th August 1949 until the test-ban treaty of 1963. The effects of the weapons testing on the local population is only now becoming widely known. Levels of cancers and cataracts are significantly higher than in uneffected populations, and there are also high levels of some lung, bone, skin and digestive conditions. Perhaps the most important information relates to cataracts, previously thought to be caused by single large bursts of radiation. Regulatory authorities worldwide will need to tighten the safety limits for eye radiation exposure to these findings. (U.K.).

Energy Technology Data Exchange (ETDEWEB)

Advanced techniques for focused-ion-beam (FIB) device modification have been developed for complex, multistep modifications to circuitry on planar chip technology. Applying gas-assisted etching (GAE) techniques for high-aspect-ratio milling and the selective milling of both conductive and insulating films enhances process latitude. Localized ion-beam-induced deposition of an insulating film provides reconstructive capability in previously modified areas. The application of both techniques for complex device modification on VSLI devices fabricated with CMOS process technology is reviewed. (UK).

Energy Technology Data Exchange (ETDEWEB)

Although rovs (remotely operated vehicles) and AUVs (autonomous underwater vehicles) are playing ever increasing roles in the development of underwater fields, surprise is expressed that oil companies are not supporting the necessary research and development. The situation was discussed at this year's annual Association of Diving Contractors and Marine Technology Society in Houston. Some of the technical problems associated with operating the vehicles in deeper and deeper water were discussed. Although demand for the vehicles is falling in the North Sea, the Gulf of Mexico is seen as the next growth area. (uk)

International Nuclear Information System (INIS)

A conceptual framework is proposed within which the notion of risk as normally used in risk assessment (RA) could be enlarged in line with the real substance of social issues of technology policy, to help avoid RA's threatened irrelevance to social decision making. It is argued that the frequent organizational incoherence and thus the unviability of modern technology arises from 'social alienation' between the innovation-commitment phase and the implementation of the technology in society. The roles of technical elites and of particular concepts of technology in this alienation are emphasized. One of the case studies deals with 'Nuclear power - myths of scientific and organizational realism' and discusses the UK nuclear 'programme' and the Three Mile Island accident. (author).

British Library Electronic Table of Contents (United Kingdom)

Data breaches, regularly in the news thanks to absent-minded employees or malicious hackers, are a real threat about which any company involved in the storing or transfer of data needs to be aware. And this isn't just about reputation and privacy - it has a real financial impact, too. In March 2010 the Ponemon Institute revealed that the cost of a data breach has risen for the third consecutive year. It found that the average data breach incident cost UK organisations @$1.9m or @$71 per record, an increase of 13% on 2009, and 18% on 2008. We all know how important it is to protect our data. Clearly, customers need to be choosy about whom they trust.