uk family genetic: Topics by WorldWideScience.org

Association between a specific apolipoprotein B mutation and familial defective apolipoprotein B-100.

Despite their ecological and economical importance, fishes of the family Ariidae are still genetically and cytogenetically poorly studied. Among the 133 known species of ariids, only eight have been...Full Text Available

2010-04-01

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Anticipation in familial lattice corneal dystrophy type I with R124C mutation in the TGFBI (BIGH3) gene

Familial defective apolipoprotein (apo) B-100 is a genetic disease that leads to hypercholesterolemia and to an increased serum concentration of low density lipoproteins that bind defectively to the...Full Text Available

1989-01-01

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Mutations in RNA Binding Protein Gene Cause Familial Dilated Cardiomyopathy

PurposeTo report the clinical, ophthalmic, and genetic characteristics for lattice corneal dystrophy type I (LCDI) in a Chilean family.MethodsSix...Full Text Available

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The epidemiology of Graves' disease: Evidence of a genetic and an environmental contribution

ObjectivesWe sought to identify a novel gene for dilated cardiomyopathy (DCM).BackgroundDCM is a heritable, genetically...Full Text Available

2009-09-01

6

British Library Electronic Table of Contents (United Kingdom)

Previous family and twin studies have indicated that Graves' disease has a heritable component. Family studies have also shown that some autoimmune disease cluster in families and genetic studies have been able to show shared susceptibility genes. In the present nation-wide study we describe familial risk for Graves' disease among parents and offspring, singleton siblings, twins and spouses with regard to age of onset, gender and number and type of affected family members. Additionally familial association of Graves' disease with any of 33 other autoimmune and related conditions was analyzed. The Swedish Multigeneration Register on 0-75-year-old subjects was linked to the Hospital Discharge Register from years 1987-2007. Standardized incidence ratios (SIRs) were calculated for individuals ...

2010-01-01

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Cummins Turbo Technologies launches new family of turbochargers for smaller diesel engines at IAA Hannover - Public Service

Polymorphisms associated with type 2 diabetes in familial longevity: The Leiden Longevity Study

...Cummins Turbo Technologies launches new family of turbochargers for smaller diesel engines at IAA Hannover, public service, publicservice.co.uk Cummins Turbo Technologies ...launches new family of turbochargers for smaller diesel engines at IAA Hannover Cummins Turbo Technologies launches new family of turbochargers for smaller diesel engines at IAA ...Facebook Delicious Cummins Turbo Technologies launches new family of turbochargers for smaller diesel engines at IAA Hannover Cummins Turbo Technologies, a global engineering leader ...turbocharger technology, launched a new range of diesel turbochargers specifically designed for diesel engines from 2 -5 litre capacity today at IAA Hannover. Cummins ...

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Persistent Staphylococcus aureus Colonization Is Not a Strongly Heritable Trait in Amish Families

Human longevity is in part genetically determined, and the insulin/IGF-1 signal transduction (IIS) pathway has consistently been implicated. In humans, type 2 diabetes is a frequent disease that results...Full Text Available

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Mutation analysis of 272 Spanish families affected by autosomal recessive retinitis pigmentosa using a genotyping microarray

About 20% of adults are persistently colonized with S. aureus in the anterior nares. Host genetic factors could contribute susceptibility to this phenotype. The objective of...Full Text Available

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Identification of genetic variation and haplotype structure of the canine ABCA4 gene for retinal disease association studies

PurposeRetinitis pigmentosa (RP) is a genetically heterogeneous disorder characterized by progressive loss of vision. The aim of this study was to identify the causative mutations...Full Text Available

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Strikingly different penetrance of LHON in two Chinese families with primary mutation G11778A is independent of mtDNA haplogroup background and secondary mutation G13708A

Over 200 mutations in the retina specific member of the ATP-binding cassette transporter super-family (ABCA4) have been associated with a diverse group of human retinal diseases....Full Text Available

2010-10-01

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British Library Electronic Table of Contents (United Kingdom)

The penetrance of Lebers hereditary optic neuropathy (LHON) in families with primary mitochondrial DNA (mtDNA) mutations is very complex. Matrilineal and nuclear genetic background, as well as environmental factors, have been reported to be involved in different affected pedigrees. Here we describe two large Chinese families that show a striking difference in the penetrance of LHON, in which 53.3% and 15.0% of members were affected (Pin vivo mitochondrial oxidative metabolism as described in a previous study. Evolutionary analysis failed to indicate any putatively pathogenic mutation that cosegregated with G11778A in these two pedigrees. Our results suggest that the variable penetrance of LHON in the two Chinese families is independent of both their mtDNA haplotype background and a seconda...

2008-01-01

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Survey of radiation doses to patients from the diagnostic use of X-rays

The National Radiological Protection Board is to carry out a survey of doses received by patients from the diagnostic use of X-rays, beginning in June 1977, and carried out at over 100 National Health Service hospitals. Details are given of the reasons for carrying out the survey and the survey objectives. The survey working methods are discussed, together with methods of calculation of the genetically significant dose. The radiation doses will be measured by a thermoluminescent dosimeter developed specially for the survey. (U.K.).

1977-06-01

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Introduction to Genetic Algorithms

...The RSPB: Great crested grebe A delightfully elegant waterbird with ornate head plumes which led to its being hunted for its feathers, almost leading to its extermination from the UK. E-mail to a friendE-newsletterContact us Home England Northern Ireland Scotland Wales About Overview Awards & recognition Contact us Facts and figures History How we are run Inspiring work Job vacancies Looking to the future Media centre Offices The RSPB view ...status: Green Listen Get Flash player Play sound 1 videoLatin name Podiceps cristatusFamily Grebes (Podicipedidae)Overview A delightfully elegant waterbird with ornate head plumes which led to its being hunted for its feathers, almost leading to its extermination from the UK. They dive to feed and also to escape, preferring this to flying. On land they are clumsy because their feet are placed so far back on their bodies. ...

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Genetic Variation of Lodgepole Pine, Pinus contorta var. latifolia, Chemical and Physical Defenses that Affect Mountain Pine Beetle, Dendroctonus ponderosae, Attack and Tree Mortality

Introduction to Genetic Algorithms

2007-01-01

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British Library Electronic Table of Contents (United Kingdom)

Plant secondary chemistry is determined by both genetic and environmental factors, and while large intraspecific variation in secondary chemistry has been reported frequently, the levels of genetic variation of many secondary metabolites in forest trees in the context of potential resistance against pests have been rarely investigated. We examined the effect of tree genotype and environment/site on the variation in defensive secondary chemistry of lodgepole pine, Pinus contorta var. latifolia, against the fungus, Grosmannia clavigera (formerly known as Ophiostoma clavigerum), associated with the mountain pine beetle, Dendroctonus ponderosae. Terpenoids were analyzed in phloem samples from 887, 20-yr-old trees originating from 45 half-sibling families planted at two sites. Samples were coll...

2011-01-01

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The Phenomics and Expression Quantitative Trait Locus Mapping of Brain Transcriptomes Regulating Adaptive Divergence in Lake Whitefish Species Pairs (Coregonus sp.)

Molecular cloning of the N-terminus of GTBP

We used microarrays and a previously established linkage map to localize the genetic determinants of brain gene expression for a backcross family of lake whitefish species pairs (Coregonus sp.). Our...Full Text Available

2008-09-01

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Absence of linkage of apparently single gene mediated ADHD with the human syntenic region of the mouse mutant coloboma

Defects in mismatch repair genes cause the genetic instability characteristic of hereditary nonpolyposis colorectal cancer and a subset of sporadic colon tumors. The newest member of the mismatch repair gene family, GTBP, has recently been identified as a partial cDNA. Here, we describe the isolation of its 5{prime} terminus, allowing definition of the entire coding region. Several polymorphisms within the 5{prime} end were identified and are presented. 13 refs., 1 fig.

1996-02-01

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Genetic and physical location of the gene for Stargardt`s disease and further evidence for genetic homogeneity

Attention deficit disorder (ADHD) is a complex biobehavioral phenotype which affects up to 8% of the general population and often impairs social, academic, and job performance. Its origins are heterogeneous, but a significant genetic component is suggested by family and twin studies. The murine strain, coloboma, displays a spontaneously hyperactive phenotype that is responsive to dextroamphetamine and has been proposed as a genetic model for ADHD. Coloboma is a semi-dominant mutation that is caused by a hemizygous deletion of the SNAP-25 and other genes on mouse chromosome 2q. To test the possibility that the human homolog of the mouse coloboma gene(s) could be responsible for ADHD, we have carried out linkage studies with polymorphic markers in the region syntenic to coloboma (20p11-p12). Five families in which the pattern of inheritance of ADHD appears to be autosomal dominant were studied. ...

1995-12-18

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Assessing the Significance of Above- and Belowground Carbon Allocation of Fast- and Slow-Growing Families of Loblolly Pine - Final Report

Stargardt`s disease is inherited as an autosomal recessive condition characterized by a juvenile macular dystrophy. Genetic linkage analysis recently assigned the disease locus to chromosome 1p21-p13 with the best estimate for location of the gene near the locus D1S435. We performed linkage analysis in 34 North American families and 2 inbred families from the Kingdom of Saudi Arabia with 12 highly polymorphic markers on chromosome 1p flanking D1S435 between D1S207 and D1S223 and report significant linkage for all 12 markers with no evidence for genetic heterogeneity. Two-point linkage analysis demonstrated the Stargardt`s disease locus and D1S435 are linked with a maximum lod score of 17.17 at a recombination fraction of 1%. The markers UT851, D1S188, D1S424, UT2069, and D1S236 also demonstrated recombination fractions of 1% or less with two-point lod scores of 15.86, 21.93, 16.41, 20.36, and 17.37, ...

1994-09-01

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UK seasonal weather summary spring 2011

During this project we experimentally evaluated the below-ground biomass and carbon allocation and partitioning of four different fast- and slow-growing families of loblolly pine located in Scotland County, NC, in an effort to increase the long-term performance of the crop. The trees were subjected to optimal nutrition and control since planting in 1993. Destructive harvests in 1998 and 2000 were used for whole?plant biomass estimates and to identify possible family differences in carbon acquisition (photosynthesis) and water use efficiency. At regular intervals throughout each year we sampled tissues for carbohydrate analyses to assess differences in whole-tree carbon storage. Mini rhizotron observation tubes were installed to monitor root system production and turnover. Stable isotope analysis was used to examine possible functional differences in water and nutrient acquisition of root systems between the various ...

2001-03-01

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Not Available

2011-07-01

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Sequences of versatile, broad-host-range vectors of the RK2 family.

...ukDirect dial: 020 7630 4521 __________________...ukDirect dial: 020 7630 4515 __________________...ukDirect dial: 020 7630 4522 __________________...ukDirect dial: 020 7630 4519 __________________...

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Strikingly different penetrance of LHON in two Chinese families with primary mutation G11778A is independent of mtDNA haplogroup background and secondary mutation G13708A

Plasmid pRK404-a smaller derivative of RK2-is a tetracycline-resistant broad-host-range vector that carries a multiple cloning site and the lacZ(alpha) peptide that enables blue/white selection for cloned inserts in Escherichia coli. We present herein the complete and annotated sequence of pRK404 and three related vectors-pRK437, pRK442, and pRK442(H). These derivatives have proven to be valuable tools for genetic manipulation in Gram-negative bacteria. The knowledge of their complete sequences will facilitate efficient future engineering of them and will enhance their general applicability to the design of genetic systems for use in organisms for which new genomic sequence data are becoming available.

2003-07-01

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Strikingly different penetrance of LHON in two Chinese families with primary mutation G11778A is independent of mtDNA haplogroup background and secondary mutation G13708A

The penetrance of Leber's hereditary optic neuropathy (LHON) in families with primary mitochondrial DNA (mtDNA) mutations is very complex. Matrilineal and nuclear genetic background, as well as environmental factors, have been reported to be involved in different affected pedigrees. Here we describe two large Chinese families that show a striking difference in the penetrance of LHON, in which 53.3% and 15.0% of members were affected (P < 0.02), respectively. Analysis of the complete mtDNA genome of the two families revealed the presence of the primary mutation G11778A and several other variants suggesting the same haplogroup status G2a. The family with higher penetrance contained a previously described secondary mutation G13708A, which presents a polymorphism in normal Chinese samples and does not affect in vivo mitochondrial oxidative metabolism as described in a ...

2008-08-25

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Home radon levels and seasonal correction factors for the Isle of Man

The penetrance of Leber's hereditary optic neuropathy (LHON) in families with primary mitochondrial DNA (mtDNA) mutations is very complex. Matrilineal and nuclear genetic background, as well as environmental factors, have been reported to be involved in different affected pedigrees. Here we describe two large Chinese families that show a striking difference in the penetrance of LHON, in which 53.3% and 15.0% of members were affected (P < 0.02), respectively. Analysis of the complete mtDNA genome of the two families revealed the presence of the primary mutation G11778A and several other variants suggesting the same haplogroup status G2a. The family with higher penetrance contained a previously described secondary mutation G13708A, which presents a polymorphism in normal Chinese samples and does not affect in vivo mitochondrial oxidative metabolism as described in a previous study. ...

2008-08-25

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Ionizing radiation dose levels due to home radon can rise to levels that would be illegal for workers in the nuclear industry. It is well known that radon levels within homes and from home to home, and also from month to month, vary considerably. To define an Isle of Man radon seasonal correction factor, readings were taken in eight homes over a 12 month period. An average island indoor exposure of 48 Bq m{sup -3} (range 4-518 Bq m{sup -3}) was determined from 285 homes selected from a cohort of 1300 families participating in the European Longitudinal Study of Pregnancy and Childhood (ELSPAC) in the Isle of Man. This compares with a UK home average of 20 Bq m{sup -3} and a European Union average (excluding UK) of 68 Bq m{sup -3}. Ten homes of those measured were found to have radon levels above the National Radiological Protection Board 200 Bq m{sup -3} action level. There are 29 377 homes on the Isle of Man, suggesting ...

2000-08-01

28

Amyloidosis

UK-ENGLAND/LONDON, THAMES R.,HOLBORN AREA

The subjects covered in this Symposium range through almost every clinical medical specialty. From an average of one paper in each of the past three Symposiums, the explosive interest in cerebral amyloidosis has led to the presentation of 12 papers on this subject in the present volume. The genetically predisposed familial amyloidotic processes, such as the polyneuropathies and familial Mediterranean fever have also stimulated extensive and intriguing investigations which have revealed the striking effect of a single amino acid substitution in transforming a normal protein into a lethal ''amyloidogenic'' one. This Symposium clearly depicts the advances since the first amyloid fibril protein was definitively identified and defined 14 years ago. Since all amyloid fibril proteins so far described are variants of normal proteins, attention to gene abnormalities now becomes a significant focus as well as the pathogenic sequences ...

1984-11-09

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Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease

UK-ENGLAND/LONDON, THAMES R.,HOLBORN AREA

2008-01-01

30

British Library Electronic Table of Contents (United Kingdom)

Meningococcal disease is an infection caused by Neisseria meningitidis. Genetic factors contribute to host susceptibility and progression to disease, but the genes responsible for disease development are largely unknown. We report here a genome-wide association study for host susceptibility to meningococcal disease using 475 individuals with meningococcal disease (cases) and 4,703 population controls from the UK. We performed, in Western European and South European cohorts (consisting of 968 cases and 1,376 controls), two replication studies for the most significant SNPs. A cluster of complement factor SNPs replicated independently in both cohorts, including SNPs within complement factor H (CFH) (rs1065489 (p.936D

2010-01-01

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UK Defence Acquisition Process for NEC: Transaction ...

... Page 31. UK Defence Acquisition Process for NEC: Transaction Governance within an Integrated ... Bilateral Governance UK Defence Acquisition ...

2009-04-22

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Layout 1

UK-ENGLAND/CLACTON-ON-SEA, R. COLNE, COAST, AGR.

Competitiveness of the UK furniture manufacturing industry.2010 ...is clear from the study that the UK furniture manufacturing industry has responded to the challenge of ...Competitiveness of the UK furniture manufacturing industry.2010

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[Pulmonary vascular manifestations in hereditary hemorrhagic telangiectasia].

UK-ENGLAND/CLACTON-ON-SEA, R. COLNE, COAST, AGR.

2009-01-01

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Malignant transformation of diploid human fibroblasts by transfection of oncogenes

Hereditary hemorrhagic telangiectasia (Osler-Rendu-Weber disease) is a genetic disorder with autosomal dominance, variable penetrance, and an estimated prevalence of 1/10,000 inhabitants in France. Diagnosis is based on clinical criteria including epistaxis, telangiectasia, visceral manifestations, and familial occurrence. Pulmonary arteriovenous malformations, present in 15-33% of patients, are its primary visceral complications. The disease may be revealed by infectious and ischemic neurological manifestations due to paradoxical embolism. The high frequency of neurologic complications even in asymptomatic patients justifies systematic screening for pulmonary arteriovenous malformations. Treatment of these malformations is based on percutaneous transcatheter coil embolization of the feeding artery. Pulmonary arterial hypertension is rare in this disease. It may be due to systemic arteriovenous shunting in the liver, which increases cardiac ...

2005-11-01

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A YAC contig encompassing the recessive Stargardt disease gene (STGD) on chromosome 1p

This document consist of brief reports prepared by postdoctoral students supported by the project, each describing his accomplishments under the grant. Topics include (1) Malignant Transformation of MSU-1. 1 Cells by Gamma Radiation, (2) Correlation between Levels of ras Expression and Presence of Transformed Phenotypes Including Tumorigenicity, Using a Modulatable Promoter, (3) Relation between Specific rad Oncogene Expression, (4) Correlation of Genetic Changes in Fibroblastic Tumors with Malignancies, (5)Transformation of MSU-1.1 Cells by sis Oncogene, (6) Malignant Transformation of MSU-1.0 Cells, (7) Correlation of Urokinase Plasminogen Activation (mu-PA) with Malignant Phenotype, (8)Two Dimensional Gel Electrophoresis Studies of the Proteins of the Major Cell Strains of the MSU-1 Family of Cells, and (9) Correlation between Proteinase Activity Levels and Malignancy.

1992-01-01

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Genetic and physical mapping of the Chediak-Higashi syndrome on chromosome 1q42-43

Stargardt disease (STGD) and fundus flavimaculatus are infrequent autosomal recessive conditions characterized by a juvenile macular dystrophy and variable degrees of peripheral retinal changes. Linkage analysis performed in 47 STGD/fundus flavimaculatus families demonstrated significant linkage to 13 polymorphic DNA markers on chromosome 1p. The maximum combined two-point lod score was 32.7 (maximum recombination fraction [{theta}{sub max}] = .006) with the polymorphic marker D1S188. Our data demonstrate that STGD and fundus flavimaculatus are the same disorder clinically and genetically and provide further evidence for genetic homogeneity of this phenotype. Analysis of recombination on disease chromosomes placed the STGD gene within a 4-cM interval between markers D1S435 and D1S236. A physical map was constructed of a YAC contig flanking STGD, from markers D1S500 to D1S495, and includes the critical interval delineated by ...

1995-12-01

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Work and family--allies or enemies? what happens when business professionals confront life choices

The Chediak-Higashi syndrome (CHS) is a severe autosomal recessive condition, features of which are partial oculocutaneous albinism, increased susceptibility to infections, deficient natural killer cell activity, and the presence of large intracytoplasmic granulations in various cell types. Similar genetic disorders have been described in other species, including the beige mouse. On the basis of the hypothesis that the murine chromosome 13 region containing the beige locus was homologous to human chromosome 1, we have mapped the CHS locus to a 5-cM interval in chromosome segment 1q42.1-q42.2. The highest LOD score was obtained with the marker D1S235 (Z{sub max} = 5.38; {theta} = 0). Haplotype analysis enabled us to establish D1S2680 and D1S163, respectively, as the telomeric and the centromeric flanking markers. Multipoint linkage analysis confirms the localization of the CHS locus in this interval. Three YAC clones were found to cover the entire region in a contig ...

1996-09-01

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Pop : Phonophani "Genetic Engineering" / Erkki Luuk

Work and family--allies or enemies?

2000-01-01

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Index Scriptorium Estoniae

Heliplaadist

2001-01-01

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Extreme sensitivity of some intestinal crypt cells to X and #gamma# irradiation

Bomb "1"4C and human radiation burden

Reference is made to Cheng and Leblond (Amer. J. Anat.; 141:537 (1974)) who used tritiated thymidine to kill cells synthesising DNA in the crypts of the small intestine. Amongst their findings was that very low doses caused measurable cell killing and that the killing was not random throughout the crypt but occurred selectively at the crypt base where stem cells are presumably located. It is here reported that the presence of hypersensitive cells at the base of the crypts can be demonstrated after whole-body X- or gamma-irradiation, and the time sequence for the production and loss of the killed cells is described together with their dose-response relationship. The studies were conducted on mice. The data were expressed as surviving rather than killed cells, and it was established that the crypt are amongst the most sensitive of mammalian cells. The mechanism by which these sensitive cells are killed is not known, but DNA damage can be detected. The vital stem cells may lack any means ...

1977-10-01

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Geothermal heat pumps - gaining ground in the UK and worldwide

Following the publication (Stenhouse and Baxter, Nature; 267:828 (1977)) of the levels of bomb "1"4C and the residence times of carbon in the human body, excess radiation burdens from this radioisotope are evaluated under the assumption that no radiation dose, however small, can be regarded as entirely harmless biologically. The estimated annual absorbed dose attributable to "1"4C both natural and man-made for 1953-1973 and similar predicted figures for 1975-2025 are shown graphically. The cumulated doses to gonads (over 30 yr) and to bone marrow and bone-lining cells (over 60 yr) and also estimates of the biological damage to reproductive cells from "1"4C #beta#-irradiation (30 yr accumulated dose) are presented. It is concluded from both genetic and somatic considerations, that the potential human radiation burden due to artificially produced "1"4C calculated using the assumptions stated is certainly significant and, therefore, cannot be dismissed. However, ...

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Geothermal heat pumps - gaining ground in the UK and worldwide

This 2001 edition of the guide to UK renewable energy companies examines the geothermal heat pump sector, and discusses the technology involved, installations of geothermal heat pumps, the activity in the UK market with increased interest in UK geothermal heat pump products from abroad, and developments in the building sector. The UK government's increased support for the industry including its sponsorship of the Affordable Warmth programme, and the future potential of ground source systems are discussed.

2001-07-01

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Medical Student Outcomes after Family-Centered Bedside Rounds

This 2001 edition of the guide to UK renewable energy companies examines the geothermal heat pump sector, and discusses the technology involved, installations of geothermal heat pumps, the activity in the UK market with increased interest in UK geothermal heat pump products from abroad, and developments in the building sector. The UK government's increased support for the industry including its sponsorship of the Affordable Warmth programme, and the future potential of ground source systems are discussed.

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ObjectiveFamily-centered bedside rounds (FCBR) are recommended to improve trainee education, patient outcomes, and family satisfaction. However, bedside teaching...Full Text Available

2011-09-01

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UK CDHF for STP UK

Increasing the opportunities for UK-Canada collaboration

Original holdings are now kept by the World Data Centre C1 at RAL: http://wdcc1. bnsc.rl.ac.uk MODS DOY = 246 ADID_REF Not applicable LOGICAL_FILE_ID ...

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Survey of Families with Children

This paper outlines the opportunities for UK-Canada collaboration/feasibility studies in areas that include novel research into waste management and decommissioning. A number of Universities in the UK have programs relevant to such collaborations in areas such as fuels; thermal hydraulics, reactor system and materials.

2007-06-03

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Nuclear waste plans enter critical phase

heterogeneity bias Static models: Other models:

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Gordon Research Conference on High Temperature ...

A brief article considers the possible result of the enquiry into Nirex`s plan to build an underground rock laboratory at Sellafield in relation to radioactive waste disposal in the UK. (UK).

1996-10-31

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... (Argonne Nat. Lab., Speaker: M. Rand (AERE Harwell, UK) ... 19 - Discussion Leader: P. Potter (AERE Harwell, UK) Speaker: YA Chang (Univ. ...

1984-12-03

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BOOKMARKS:

Genetics, Genomics, and Molecular Biology

on practical projects such as woodland management, limestone grassland management, cattle management, conflict management and education. ...Cathy Heaton Telephone 01772 892400 Email cenquiries@uclan.ac.uk www.uclan.ac.uk/schoolbne

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SLC9A9 mutations, gene expression, and protein-protein interactions in rat models of attention-deficit/hyperactivity disorder

Genetics, Genomics, and Molecular Biology USGS scientists develop and integrate new genetic and molecular techniques into systematic analyses to describe individuals and populations of fish .....

52

British Library Electronic Table of Contents (United Kingdom)

Abstract SLC9A9 (solute carrier family 9, member 9, also known as Na+/H+ exchanger member (NHE9)) is a membrane protein that regulates the luminal pH of the recycling endosome, an essential organelle for synaptic transmission and plasticity. SLC9A9 has been implicated in human attention deficit hyperactivity disorder (ADHD) and in rat studies of hyperactivity. We examined the SLC9A9 gene sequence and expression profile in prefrontal cortex, dorsal striatum and hippocampus in two genetic rat models of ADHD. We report two mutations in a rat model of inattentive ADHD, the WKY/NCrl rat, which affect the interaction of SLC9A9 with calcineurin homologous protein (CHP). We observed an age-dependent abnormal expression of SLC9A9 in brains of this inattentive model and in the Spontaneous Hypertensi...

2011-01-01

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Human tissue factor pathway inhibitor (TFPI) gene: Complete genomic structure and localization on the genetic map of chromosome 2q

Guide to UK renewable energy companies 2001. 6. ed.

Tissue factor pathway inhibitor (TFPI), a protease inhibitor that circulates in association with plasma lipoproteins (VLDL, LDL and HDL), helps to regulate the extrinsic blood coagulation cascade. The authors have cloned a 125-kb genomic region containing the entire human TFPI gene on six overlapping cosmids and prepared a restriction map of this contig to clarify gene structure. More than half (45 kb) of the 85-kb gene is occupied with 5[prime] noncoding elements: coding begins at exon 3. A HindIII RFLP identified with one cosmid was genotyped in the CEPH panel of 559 reference families. Linkage analysis using markers on human chromosome 2 located the TFPI gene on 2q, 36 cM proximal to D2S43(pYNZ15) and 13 cM distal to the crystalline [gamma]-polypeptide locus CRYGP1(p5G1). 31 refs., 3 figs., 3 tabs.

1993-08-01

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Alluvial fan and wetland interactions: evidence of seasonal slope wetlands from the Silurian of south central Wales, UK

This 2001 edition of the guide to UK renewable companies and equipment and service providers presents summaries of the different industry sectors covering wind power, photovoltaics, solar water heating, geothermal heat pump, hydroelectric power, marine current and wave technology, bioenergy, power generation from landfill gas, energy from waste, and cogeneration. A UK company classification listing and index is provided along with listing of UK organisations and companies and an index of advertisers.

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After the SPS inaugural ceremony

Not Available

2011-06-01

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CERN Multimedia

Mervyn Hine (right) with two guests from UK

1977-01-01

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biotechnological studies on the effect of gamma rays on peanut

Technology assessment and resource allocation for predictive genetic testing: A study of the perspectives of Canadian genetic health care providers

local peanut cultivars Giza 4 and Giza 5 were exposed to different doses ( 50,100,150,200,250 and 300 Gy)to Co "6"0 gamma ray source . all irradiated materials were cultivated to give the M_1 and M_2 generation , then high yielding mutants were selected from the M_2 generation and cultivated separately to give the M_3 generation. some yield component traits were measured for the three generations (M_1,M_2 and M_3) and M_3 families.variations observed in these traits were attributed to genetic factors. the M_3 selected mutants were artificially infected by aspergillus flavus L spores (aflatoxins-B1 and B2 groups-producer strain). aflatoxin concentrations were estimated and the analysis showed that aflatoxin concentrations in seeds of the M_3 selected mutants from cultivar Giza 4 were higher than those in seeds of the M3 mutants selected from cultivar Giza 5. however, the concentration of aflatoxin increased when the yield ( weight of seeds per ...

2007-01-01

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Molecular Genetics of Emericella nidulans Sexual Development

BackgroundWith a growing number of genetic tests becoming available to the health and consumer markets, genetic health care providers in Canada are faced with the challenge of developing...Full Text Available

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Genetic screening: The vista of genomic medicine

Full Text Available

2009-09-01

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Pyridoxine dependent epilepsy and antiquitin deficiency Clinical and molecular characteristics and recommendations for diagnosis, treatment and follow-up.

The accelerating development of biochemical and DNA-based diagnostic tests for human genetic conditions in the last decade has engendered a revolution in genetic diagnosis. Both genetic testing and...Full Text Available

2011-01-01

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Use of information sources by family physicians: a literature survey.

Antiquitin (ATQ) deficiency is the main cause of pyridoxine dependent epilepsy characterized by early onset epileptic encephalopathy responsive to large dosages of pyridoxine. Despite seizure control most patients have intellectual disability. Folinic acid responsive seizures (FARS) are genetically identical to ATQ deficiency. ATQ functions as an aldehyde dehydrogenase (ALDH7A1) in the lysine degradation pathway. Its deficiency results in accumulation of ?-aminoadipic semialdehyde (AASA), piperideine-6-carboxylate (P6C) and pipecolic acid, which serve as diagnostic markers in urine, plasma, and CSF. To interrupt seizures a dose of 100mg of pyridoxine-HCl is given intravenously, or orally/enterally with 30mg/kg/day. First administration may result in respiratory arrest in responders, and thus treatment should be performed with support of respiratory management. To make sure that late and masked response is not missed, treatment with oral/enteral pyridoxine should be ...

2011-05-24

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Life Stress, Maternal Optimism, and Adolescent Competence in Single Mother, African American Families

Analysis of the use of information sources by family physicians is important for both practical and theoretical reasons. First, analysis of the ways in which family physicians handle information may...Full Text Available

1995-01-01

63

Health and function of participants in the Long Life Family Study: A comparison with other cohorts

Although research demonstrates many negative family outcomes associated with single-parent households, little is known about processes that lead to positive outcomes for these families. Using...Full Text Available

2010-08-01

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Genome-Wide Identification and Evolutionary Analysis of the Animal Specific ETS Transcription Factor Family

Individuals from families recruited for the Long Life Family Study (LLFS) (n= 4559) were examined and compared to individuals from other cohorts to determine whether the recruitment targeting longevity...Full Text Available

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Evaluating Patients with Chronic Pain and their Families

The ETS proteins are a family of transcription factors (TFs) that regulate a variety of biological processes. We made genome-wide analyses to explore the classification of the ETS gene family. We identified...Full Text Available

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After-Hours Information Given by Telephone by Family Physicians in Ontario

Inclusion of family members in the assessment of patients with chronic pain can improve outcomes. Family functioning can be assessed in four basic areas: boundaries, power, communication, and intimacy....Full Text Available

1991-02-01

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A study on multi-cultural family wives adapting to Korean cuisine and dietary patterns

This study describes instructions for after-hours care offered by family physicians' offices when patients telephone the practice. Randomly selected (n=1,680) Ontario family physicians and general practitioners...Full Text Available

2009-11-01

68

International Networking for Young Scientists Working on Renewable Energy - China:UK Partnership - Revision 3

With the increase in multi-cultural families, Korea is seeing a rapid increase in immigrated housewives, who are closely related to food culture. However, studies for the diet of multi-cultural families,...Full Text Available

2010-10-01

69

Stability and Change in Family Structure and Maternal Health Trajectories

ObjectivesThe International Network for Young Scientists is holding a China:UK workshop in Shanghai in December. It will focus specifically on Renewable Energy. Profs Wallace and Infield have been invited to be the UK academic partners. Dr. Luo Yong Hao, Deputy Director of Institute for Thermal Engineering at Shanghai Jiao Tong University is the lead Chinese academic partner. British Council Shanghai are the co-ordinators of the event and have obtained some limited funding to cover the costs.. ~%~~%~T [continued...]DescriptionReseachers are being brought together at a China:UK Renewable Energy Research Workshop. They will define and initiate joint research and staff/student exchanges between Chinese and UK universities to advance renewable energy and related research to meet the energy needs of both China and the UK.~%~

2007-01-07

70

Coping Strategies of Family Members of Hospitalized Psychiatric Patients

Recent increases in births to unmarried parents, and the instability surrounding these relationships, have raised concerns about the possible health effects associated with changes in family...Full Text Available

2008-04-01

71

Automated radon radiometers of RRA family

This exploratory research paper investigated the coping strategies of families of hospitalized psychiatric patients and identified their positive and negative coping strategies. In this paper, the coping...Full Text Available

2011-01-01

72

Systemic bioavailability of hydrofluoroalkane (HFA) formulations of fluticasone/salmeterol in healthy volunteers via pMDI alone and spacer

Two automated radiometers of RRA family designed for radon concentration measurements are presented. Principal performance specifications and promising applications of the radiometers are presented.

1999-08-01

73

AIMTo compare a test version of HFA fluticasone/salmeterol (FP/SM) combination inhaler (Neolab, UK) with the reference product Seretide (GlaxoSmithKline, UK).METHODSAn...Full Text Available

2010-06-01

74

Stumbling in the smog

The pollutants from the exhausts of internal combustion engines cause a range of illnesses and are the main source of atmospheric contamination. This article explores the options for curbing pollution in the UK including catalytic converters, electric cars, and natural gas cars. It is likely that the onus will remain with the car manufacturers for developing solutions. (UK)

1994-11-10

75

SBNE-Cover1

Renewable energy and the ODA energy efficient strategy

on practical projects such as woodland management, limestone grassland management, cattle management, conflict management and education. ...Cathy Heaton Telephone 01772 892400 Email cenquiries@uclan.ac.uk www.uclan.ac.uk/schoolbne

76

Cross-sectional measures and modelled estimates of blood alcohol levels in UK nightlife and their relationships with drinking behaviours and observed signs of inebriation

The energy strategy of the UK Overseas Development Administration is outlined with specific emphasis on energy efficiency and renewable energies. Based on 29 case studies concerning projects and programmes in both developed and developing countries, critical success factors for renewable energy projects are identified. UK)

1995-12-31

77

British waste plans face fierce local opposition

BackgroundManagement of nightlife in UK cities focuses on creating safe places for individuals to drink. Little is known about intoxication levels as measuring total alcohol consumption...Full Text Available

78

The distribution of mass-to-light ratio with radius in M31 and M33

UK Nirex has announced four sites which it wishes to assess for the disposal of low-level and short-lived intermediate-level radioactive wastes. There is local opposition at all four of the potential sites. (U.K.).

1986-05-01

79

Technology Strategy Board

1974. Netherlands Baldwin, JE Cambridge Univ. (UK). Cavendish Lab. Reidel.;

80

Privatization of the ESI. Broadening the debate. [Electricity supply industry in the UK

Technology Strategy Board Driving Innovation ...Technology Strategy 2009-2012 ... The vision of the Technology Strategy Board is for the UK to be a global leader in innovation

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81

Electromagnetic radiation produced by a relativistic charge passing through a hole in a conducting plate

The debate over the privatization of electricity in the UK has been conducted across too narrow a terrain, being primarily concerned with regulation for optimality in the context of static, if uncertain, conditions of supply and demand. Insufficient account has been taken of dynamic agencies in formulating and bringing about progressive industrial change, something of great importance in the light of their weakness in the UK context. Consequently, a number of deficiencies in the UK ESI have been neglected in the debate over privatization and are not liable to be rectified by it in practice. (author).

1989-06-01

82

The British Furniture Confederation, the trade association representing the UK furniture manufacturing industry, is delighted to announce that the A\\

(May 1974). United Kingdom Hemp, J. Oxford Univ. (UK). Dept. of

83

...The British Furniture Confederation, the trade association representing the UK furniture manufacturing industry, is delighted to announce that the A FIRA - Furniture ...Group reformed The British Furniture Confederation, the trade association representing the UK furniture manufacturing industry, is delighted to announce that the All-Party Parliamentary ...

84

Good start to the Go Beyond Oil street campaign | Greenpeace UK

... News In Practice UK work Key facts & information Mass Balance Projects Resources & Library Technical Area Contacts Site Map Benchmarking solvent waste in the UK furniture manufacturing industry OrganisationBritish Furniture Manufacturers Ltd Project ReportSolvent Waste in Furniture Manufacturing Website: www.bfmenvironment.co.uk Return to list � RSWT | Website Design Quiet Storm Solutions Ltd Please consider upgrading your browser! If you can see this ...

85

The polymorphism architecture of mouse genetic resources elucidated using genome-wide resequencing data: implications for QTL discovery and systems genetics

... For example, moving from incentives for deepwater drilling for dirty oil to real support for renewables, and from hidden subsidies for nuclear power to transforming the UK to a thriving low carbon economy. Thanks once again to those who came along. There will be more opportunities to campaign with us soon, to help get the support we need to move the UK beyond oil. GoBeyondOilCampaigningCamden1 Comments(...

86

Genetically-engineered mouse models for pancreatic cancer: Advances and current limitations

Mouse genetic resources include inbred strains, recombinant inbred lines, chromosome substitution strains, heterogeneous stocks, and the Collaborative Cross (CC). These resources were generated through...Full Text Available

2007-07-01

87

From Classical Genetics to Quantitative Genetics to Systems Biology: Modeling Epistasis

Recently, there has been significant progress in the development of genetically-engineered mouse (GEM) models. By introducing genetic alterations and/or signaling alterations of human pancreatic cancer...Full Text Available

2011-05-10

88

Evolving hard problems: Generating human genetics datasets with a complex etiology

Gene expression data has been used in lieu of phenotype in both classical and quantitative genetic settings. These two disciplines have separate approaches to measuring and interpreting epistasis, which...Full Text Available

2008-03-01

89

Common genetic variation and susceptibility to partial epilepsies: a genome-wide association study

BackgroundA goal of human genetics is to discover genetic factors that influence individuals' susceptibility to common diseases. Most common diseases are thought to result from the...Full Text Available

90

The Effect of Self-esteem, Academic Achievement and Family Functioning of Adolescents on Hope

Partial epilepsies have a substantial heritability. However, the actual genetic causes are largely unknown. In contrast to many other common diseases for which genetic association-studies have successfully...Full Text Available

2010-07-01

91

September 2000 Number 146

Full Text Available

2001-01-01

92

Police Family Life Education Project (FLEP) Implementations, September 11, 1999, October 2, 1999, April 29, 2000 and June 24, 2000. Follow-Up Surveys of Families Who Attended Each of the Classes-Final Report.

Improved Education Some suggest that the full range of groups that deal with families and pets could benefit

93

If I Had - A Family History of Muscular Dystrophy

The major purpose of the Police Family Life Education Project (FLEP) is 'to develop and deliver a program that will provide police recruits and their immediate family members with stress management education that focuses on the role and responsibilities o...

2001-01-01

94

Diabetic Vitrectomy Surgery

... parent groups that are wonderful and lots of networking and a lot of interactions between the foundations, ...

95

An In-Hospital Family Member Cardiopulmonary Resuscitation (CPR) Education Program

... anything wrong; it could be summertime. So just vigilance with yearly exams. If you have a family ...

96

A new family of Hydroidea, together with a description of the structure of a new species of Plumularia, by W. Baldwin ...

Cardiac Arrest; Coronary Disease; Cardiovascular Risk Factors

2010-12-13

97

THE BALDWIN EFFECT AND GENETIC ASSIMILATION: REVISITING TWO MECHANISMS OF EVOLUTIONARY CHANGE MEDIATED BY PHENOTYPIC ...

Language: English ...

98

Ovine reference materials and assays for prion genetic testing

... 1111/j.1558-5646.2007.00203.x THE BALDWIN EFFECT AND GENETIC ASSIMILATION: REVISITING TWO MECHANISMS OF ... to phenotypic plast...

99

Molecular Genetics and Carcinogenesis Section

BackgroundGenetic predisposition to scrapie in sheep is associated with several variations in the peptide sequence of the prion protein gene (PRNP). DNA-based tests...Full Text Available

100

Mice as a Mammalian Model for Research on the Genetics of Aging

The Molecular Genetics and Carcinogenesis Section conducts studies using human epithelial cells to assess: activation of proto-oncogenes by chemical and physical carcinogens; inactivation and dysregulation of tumor suppressor genes by chemical and physical

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101

Liver Carcinogenesis Unit

Mice are an ideal mammalian model for studying the genetics of aging: considerable resources are available, the generation time is short, and the environment can be easily controlled, an important...Full Text Available

2011-02-08

102

Detection of genetic mutations in repetitive DNA sequences in somatic human cells after low-dose irradiation

The Liver Carcinogenesis Section uses the modern technologies of molecular biology, cell biology, protein chemistry and genetics to investigate the biochemical and genetic pathways involved in human liver cancer.

103

Browse Conditions - Genetics Home Reference

... 3-89701-147-6 0949-2224 245 p. animal cells dna genetic radiation effects

1998-03-01

104

APPLICATION OF RAPD IN THE DETERMINATION OF GENETIC FIDELITY IN MICROPROPAGATED DROSERA PLANTLETS

Home A service of the U.S. National Library of Medicine® Home Conditions Genes Chromosomes Handbook Glossary Resources Genetic Conditions > Browse Conditions 1-9 | A | B | C...

2011-09-24

105

An efficient higher order family of root finders

... K. Ishii. 1998. Determination of genetic stability in long-term micropropagated shoots of Pinus thunbergii Parl. using RAPD markers. Plant ... ...

106

British Library Electronic Table of Contents (United Kingdom)

A one parameter family of iterative methods for the simultaneous approximation of simple complex zeros of a polynomial, based on a cubically convergent Hansen-Patricks family, is studied. We show that the convergence of the basic family of the fourth order can be increased to five and six using Newtons and Halleys corrections, respectively. Since these corrections use the already calculated values, the computational efficiency of the accelerated methods is significantly increased. Further acceleration is achieved by applying the Gauss-Seidel approach (single-step mode). One of the most important problems in solving nonlinear equations, the construction of initial conditions which provide both the guaranteed and fast convergence, is considered for the proposed accelerated family. These cond...

2008-01-01

107

Multicolor FISH mapping with Alu-PCR-amplified YAC clone DNA determines the order of markers in the BRCA1 region on chromosome 17q12-q21

Late-onset Stargardt-like macular dystrophy maps to chromosome 1p13

A gene designated BRCA1, implicated in the susceptibility to early-onset familial breast cancer, has recently been localized to chromosome 17q12-q21. To date, the order of DNA markers mapped within this region has been based on genetic linkage analysis. The authors report the use of multicolor fluorescence in situ hybridization to establish a physically based map of five polymorphic DNA markers and 10 cloned genes spanning this region. Three cosmid clones and Alu-PCR-Generated products derived from 12 yeast artificial chromosome clones representing each of these markers were used in two-color mapping experiments to determine an initial proximity of markers relative to each other on metaphase chromosomes. Interphase mapping was then employed to determine the order and orientation of closely spaced loci by direct visualization of fluorescent signals following hybridization of three probes, each detected in a different color. Statistical analysis ...

1993-09-01

108

Genome Sequence of a Lancefield Group C Streptococcus zooepidemicus Strain Causing Epidemic Nephritis: New Information about an Old Disease

Stargardt`s disease (MIM 248200), originally described in 1909, is an autosomal recessive condition of childhood, characterized by a sudden and bilateral loss of central vision. Typically, it has an early onset (7 to 12 years), a rapidly progressive course and a poor final outcome. The central area of the retina (macula) displays pigmentary changes in a ring form with depigmentation and atrophy of the retinal pigmentary epithelium (RPE). Perimacular yellowish spots, termed fundus flavimaculatus, are observed in a high percentage of patients. We have recently reported the genetic mapping of Stargardt`s disease to chromosome 1p13. On the other hand, considering that fundus flavimaculatus (MIM 230100) is another form of fleck fundus disease, with a Stargardt-like retinal aspect but with a late-onset and a more progressive course, we decided to test the hypothesis of allelism between typical Stargardt`s disease and late-onset autosomal recessive fundus flavimaculatus. ...

1994-09-01

109

Assessment of generation temperatures of crude oils

Outbreaks of disease attributable to human error or natural causes can provide unique opportunities to gain new information about host-pathogen interactions and new leads for pathogenesis research. Poststreptococcal glomerulonephritis (PSGN), a sequela of infection with pathogenic streptococci, is a common cause of preventable kidney disease worldwide. Although PSGN usually occurs after infection with group A streptococci, organisms of Lancefield group C and G also can be responsible. Despite decades of study, the molecular pathogenesis of PSGN is poorly understood. As a first step toward gaining new information about PSGN pathogenesis, we sequenced the genome of Streptococcus equi subsp. zooepidemicus strain MGCS10565, a group C organism that caused a very large and unusually severe epidemic of nephritis in Brazil. The genome is a circular chromosome of 2,024,171 bp. The genome shares extensive gene content, including many virulence factors, with genetically ...

2008-08-21

110

Thai Family Health Routines: scale development and psychometric testing.

Biological marker maturity parameters were used to estimate the minimum HC generation temperatures of crude oils from Eastern Hungary. More than 50 oils and oil shows were analysed. Molecular- and homologous-ratios of biological marker compounds (triterpanes, steranes, mono- and triaromatic steroid hydrocarbons) were used as maturation parameters. The oils have at least five maturity stages, i.e. they have been generated under different thermal conditions. The highest reservoir temperature in each group was chosen as the best estimate of the groups' temperature just below the generation temperature, i.e. reservoirs of the group might be expected to be at shallower depths (lower temperatures) than those of the generation zone due to vertical migration into pools. For each maturation level, a threshold temperature range for genesis was inferred from reservoir temperatures; they are from 130-135{sup o}C for the least mature oils to 210-215{sup o}C for the most mature oils. In the ...

2000-07-01

111

The aims of the study were to develop and test the psychometric properties of the Thai Family Health Routines (TFHR) scale, a 70-item self-report questionnaire used to measure the health of Thai families through their routine behaviors in daily life. Development of the TFHR was based on the structural domains of Denham's Family Health Model. The TFHR scale was initially composed of 85 items and tested on 1,040 families living in the central region of Thailand. The confirmatory factor analysis, with an acceptable factor structure model, yielded 70 items aligned with six factors: self-care, safety and prevention, mental health behavior, family care, family caregiving, and illness care routines. The preliminary psychometric properties demonstrated that the TFHR scale had satisfactory internal consistency, criterion validity, and construct validity. The test results ...

2009-05-01

112

Primaquine

Population genetic structure of savannah elephants in Kenya: conservation and management implications

... oxygen to the tissues in the body),nicotinamide adenine dinucleotide (NADH) deficiency (a genetic condition), glucose-6- ...

113

Genome structure of cotton revealed by a genome-wide SSR genetic map constructed from a BC₁population between gossypium hirsutum and G. barbadense

Udgivelsesdato: null-null

2008-01-01

114

Genetically and somatically significant radiation doses in the radiotherapy of inflammatory and degenerative diseases

BackgroundCotton, with a large genome, is an important crop throughout the world. A high-density genetic linkage map is the prerequisite for cotton genetics and breeding. A genetic...Full Text Available

115

Genetic Stability of Magnaporthe oryzae during Successive Passages through Rice Plants and on Artificial Medium

... pathological changes patients radiation protection radiotherapy diseases

1982-10-25

116

Genetic Characterization of Encephalomyocarditis Virus Isolated from Aborted Swine Fetus in Korea

Full Text Available

2010-12-01

117

Fuel cycle options and sustainability for new nuclear build in the UK

Full Text Available

2006-10-01

118

UK's Sizewell inquiry; funny how time slips away

After a long period of stagnation in the UK, Europe and the USA, there is now a real expectation that new nuclear plants will be under construction shortly. Several factors have contributed to this change of position in the UK: the growing realisation that effective action is needed to offset greenhouse gas emissions; higher prices for fossil fuels; increasing reliance on overseas supplies of oil and gas; the limitations of wind and wave power and distribution; security of supply; the gradual realisation in the deregulated electricity generation market that nuclear power is competitive and the pending closure of most of the UK's nuclear fleet within less than 15 years. All these factors have led to a reversal of the UK Government's attitude to nuclear power, which has now ruled in favour of allowing a new generation of nuclear plants being built. This paper summarises some of the arguments that have led ...

2008-09-14

119

Sustainability literacy: the future paradigm for construction education?

Comments are made on the Public Inquiry into CEGB's proposal to construct a pressurized water reactor (PWR) at Sizewell, UK. Aspects discussed include: time elapsed and its possible effect on the result; economics of nuclear power plants compared with coal-fired power plants; changes in real sterling/dollar exchange rates; effect of mineworkers' strike; the UK electric power generating system; AGR reactors compared with PWR reactors; extension of Magnox reactor life; radioactive waste management; political decisions.

1985-03-01

120

British Library Electronic Table of Contents (United Kingdom)

Purpose - This paper seeks to analyse the hypothesis that sustainability is destined to become the operating paradigm for construction education in the UK. Design/methodology/approach - An international literature review is used to assess the relationship between sustainability and the built environment. The viewpoints of the construction-related professions are examined by analysing the accreditation policies of key professional bodies and through a survey of public sector-based UK building professionals. International and national policy initiatives on educating for sustainability are reviewed and a survey of UK universities delivering construction degrees is used to explore the environmental content of construction courses. A brief case study describes recent efforts to systematically e...

2007-01-01

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121

Youth-Family, Youth-School Relationship, and Depression

Variants within the yeast Ty sequence family encode a class of structurally conserved proteins.

This study sought to examine the association between adolescents’ relationship with family and school and depressive symptoms across ethnic/racial groups (White, Black, Hispanic, and...Full Text Available

2010-04-01

122

Treatment planning for children with attention-deficit/hyperactivity disorder: treatment utilization and family preferences

The Ty transposable elements of Saccharomyces cerevisiae form a heterogeneous family within which two broad structural classes (I and II) exist. The two classes differ by two large substitutions and...Full Text Available

1985-06-11

123

The ovalbumin gene family: complete sequence and structure of the Y gene.

BackgroundAttention-deficit/hyperactivity disorder (ADHD) is a common condition that often results in child and family functional impairments. Although there are evidence-based treatment...Full Text Available

124

The Friedreich Ataxia Critical Region Spans A 150-kb Interval on Chromosome 9q13

The "ovalbumin Y" gene, one of three which constitute the ovalbumin gene family in chicken has been completely sequenced. The exact location of exons can be derived from the comparison with the ovalbumin...Full Text Available

1982-07-24

125

Support groups for dementia caregivers - Predictors for utilisation and expected quality from a family caregiver's point of view: A questionnaire survey PART I*

By analysis of crossovers in key recombinant families and by homozygosity analysis of inbred families, the Friedreich ataxia (FRDA) locus was localized in a 300-kb interval between the X104 gene and...Full Text Available

1995-11-01

126

SLC25A4 - solute carrier family 25 (mitochondrial carrier; adenine...

BackgroundSupport groups have proved to be effective in reducing the burden on family caregivers of dementia patients. Nevertheless, little is known about the factors that influence...Full Text Available

127

Rare mutations predisposing to familial adenomatous polyposis in Greek FAP patients

The official name of this gene is "solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4." SLC25A4 is the gene's official symbol. The...

2011-08-13

128

Mutations in TPRN Cause a Progressive Form of Autosomal-Recessive Nonsyndromic Hearing Loss

BackgroundFamilial Adenomatous Polyposis (FAP) is caused by germline mutations in the APC (Adenomatous Polyposis Coli) gene. The vast majority of APC mutations...Full Text Available

129

Molecular Identification and Expression Analysis of Filaggrin-2, a Member of the S100 Fused-Type Protein Family

We performed genome-wide homozygosity mapping in a large consanguineous family from Morocco and mapped the autosomal-recessive nonsyndromic hearing loss (ARNSHL) in this family to the DFNB79...Full Text Available

2010-03-12

130

INFLUENCE OF PERCEIVED SECONDARY STIGMA AND FAMILY ON THE RESPONSE TO HIV INFECTION AMONG INJECTION DRUG USERS IN VIETNAM

Genes of the S100 fused-type protein (SFTP) family are clustered within the epidermal differentiation complex and encode essential components that maintain epithelial homeostasis and barrier functions....Full Text Available

131

Heterogeneous mutations in the human lipoprotein lipase gene in patients with familial lipoprotein lipase deficiency.

The full impact of secondary stigma (stigma directed at family) on an HIV-positive individual is unknown. This qualitative research explores perceptions of secondary stigma in the Vietnamese...Full Text Available

2010-12-01

132

Food meanings in HIV and AIDS caregiving trajectories: Ritual, optimism and anguish among caregivers in Lesotho

The DNA sequences were determined for the lipoprotein lipase (LPL) gene from five unrelated Japanese patients with familial LPL deficiency. The results demonstrated that all five patients are homozygotes...Full Text Available

1991-12-01

133

Diabetes mellitus patients' family caregivers' subjective quality of life.

The article describes the caregiving responsibility to provide food for chronically ill family members and the meanings attached to food and eating when ill created stress for family caregivers. The...Full Text Available

2011-02-05

134

Cultural and Contextual Influences on Parenting in Mexican American Families

OBJECTIVES: To assess the subjective quality of life (QOL) of family caregivers of Sudanese type-1 and type-2 diabetic outpatients, using the WHO 26-item QOL instrument, compared with a general population...Full Text Available

2006-05-01

135

Congenital anal anomalies in two families with the Opitz G syndrome.

Family stress theory can explain associations between contextual stressors and parenting. However, the theory has not been tested among Mexican Americans or expanded to include cultural-contextual...Full Text Available

2009-02-01

136

Coevolution of activating and inhibitory receptors within mammalian carcinoembryonic antigen families

Five children from two families presented to a regional neonatal surgical unit between 1959 and 1984 with congenital anal anomalies and other malformations resulting from an autosomal dominant inherited...Full Text Available

1987-11-01

137

Breaking the 1000-gene barrier for Mimivirus using ultra-deep genome and transcriptome sequencing

BackgroundMost rapidly evolving gene families are involved in immune responses and reproduction, two biological functions which have been assigned to the carcinoembryonic antigen...Full Text Available

138

Analysis of the bmp Gene Family in Borrelia burgdorferi Sensu Lato

BackgroundMimivirus, a giant dsDNA virus infecting Acanthamoeba, is the prototype of the mimiviridae family, the latest addition to the family of the nucleocytoplasmic...Full Text Available

139

An Arabidopsis thaliana methyltransferase capable of methylating farnesoic acid?

BmpA, BmpB, BmpC, and BmpD are homologous Borrelia burgdorferi lipoproteins of unknown functions, encoded by the bmp genes of paralogous chromosomal gene family 36....Full Text Available

2000-04-01

140

A new VCAN/versican splice acceptor site mutation in a French Wagner family associated with vascular and inflammatory ocular features

We previously reported the identification of a new family of plant methyltransferases (MTs), named the SABATH family, that use S-adenosyl-l-methionine (SAM) to methylate...Full Text Available

2006-04-15

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141

UK-China Bridge in Sustainable Energy and Built Environment

PurposeTo detail the highly variable ocular phenotypes of a French family affected with an autosomal dominantly inherited vitreoretinopathy and to identify the disease gene.MethodsSixteen...Full Text Available

142

ObjectivesThe primary aim is to enable China to address its energy and infrastructure issues in a sustainable manner, without hindering economic progress, with the UK benefiting from an enhanced uptake of its technology, knowledge and expertise through enhanced business opportunities and strengthened collaboration with key Chinese Institutions. ~%~~%~Objectives~%~1) To build capacity and capability in technology transfer and knowledge exploitation in Chinese and UK business and industry through practical, [continued...]DescriptionThe Chinese 11th Five-Year Plan considers Sustainable Energy Supply and Sustainable Built Environment as crucial for achieving sustainable development. Recognising the potential benefits, the UK government has actively encouraged international collaborations with China. Two Engineering Schools at Queen's University Belfast (QUB), with internationally recognised research excellence ...

2012-01-31

143

UK coal liquefaction

Guidelines for the Management of Soft Tissue Sarcomas

The National Coal Board is investigating two routes for production of oils: liquid solvent extraction and supercritical gas extraction. Both these processes are considered ready for major development to plants of the 1 t/h scale.

1980-06-01

144

Gravity_on_Spinning_Cylinders - NASA Quest

These guidelines were drawn up following a consensus meeting of UK sarcoma specialists convened under the auspices of the British Sarcoma Group and are intended to provide a framework for the multidisciplinary...Full Text Available

2010-01-01

145

Fragrance ingredient labelling in products on sale in the U.K.

You can find a discussion of time travel and Tipler's cylinder at this site: http://www.star-names.freeserve.co.uk/travel.htm ...

146

British Library Electronic Table of Contents (United Kingdom)

Summary Background The seventh amendment of the European Union (EU) Cosmetics Directive (March 2005) and the Detergents Regulations of the EU (October 2005) are now legal requirements in Europe. Cosmetic products and detergents must be labelled for 26 individual named fragrances, when present at concentrations of > 10 parts per million (p.p.m.) in leave-on products and > 100 p.p.m. in rinse-off products. Objectives To make an assessment of the exposure pattern to fragrance of the U.K. consumer and to determine the frequency with which the constituent fragrances of fragrance mix I (FM I) and fragrance mix II (FM II) are included in products currently sold in the U.K. Methods A study of perfumed cosmetic and household products available on the shelves of U.K. retailers was carried out in Jan...

2007-01-01

147

External quality control for immunocytochemistry on cytology samples: a review of UK NEQAS ICC (cytology module) results

British Library Electronic Table of Contents (United Kingdom)

I. S. Kirbis, P. Maxwell, M. S. Flear, K. Miller and M. Ibrahim External quality control for immunocytochemistry on cytology samples: a review of UK NEQAS ICC (cytology module) results Objective:- To date, external quality control for immunocytochemistry on cytology samples is provided only by the United Kingdom national external quality assessment service for immunocytochemistry and in situ hybridisation (UK NEQAS ICC & ISH). For the purpose of this study a retrospective analysis of a comprehensive collection of quality-related data regarding immunocytochemistry on cytology samples collected through this service was analysed. Methods:- The quality of immunocytochemical reactions, using on-line collected data, was analysed for the last 23 UK NEQAS ICC cytology module external quality asses...

2011-01-01

148

The Seosan County Family Planning/Maternal & Child Health Service Research Project, Korea -Project Design and Findings of the Baseline Survey-

Family Life Cycle and Deforestation in Amazonia: Combining Remotely Sensed Information with Primary Data

Full Text Available

1983-10-01

149

Association between HLA-G genotype and risk of pre-eclampsia: a case-control study using family triads

This paper examines the relationships between the socio-demographic characteristics of small

2003-01-01

150

Genetic diversity among Angus, American Brahman, Senepol and Romosinuano cattle breeds:

Udgivelsesdato: 2004-Apr

2004-01-01

151

British Library Electronic Table of Contents (United Kingdom)

Summary The objective of this study was to quantify the genetic diversity among breeds under evaluation for tropical adaptability traits that affect the performance of beef cattle at the USDA/ARS SubTropical Agricultural Research Station (STARS) near Brooksville, FL, USA. Twenty-six microsatellite loci were used to estimate parameters of genetic diversity among the breeds American Brahman, Angus, Senepol and Romosinuano; the latter was comprised of two distinct bloodlines (Costa Rican and Venezuelan). Genotypes of 47 animals from each of these STARS herds were analysed for genetic diversity and genetic distance. Using two methods, the greatest genetic distance was detected between the Costa Rican line of Romosinuano and the Senepol. Gene diversity ranged between 0.64 (Costa Rican line of R...

2007-01-01

152

Sequence analysis of the ATM gene in 20 patients with RTOG grade 3 or 4 acute and/or late tissue radiation side effects

Purpose: Patients with ataxia-telangiectasia (A-T) show greatly increased radiation sensitivity and cancer predisposition. Family studies imply that the otherwise clinically silent heterozygotes of this autosomal recessive disease run a 3.5 to 3.8 higher risk of developing cancer. In vitro studies suggest moderately increased cellular radiation sensitivity of A-T carriers. They may also show elevated clinical radiosensitivity. We retrospectively examined patients who presented with severe adverse reactions during or after standard radiation treatment for mutations in the gene responsible for A-T, ATM, considering a potential means of future identification of radiosensitive individuals prospectively to adjust dosage schedules. Material and Methods: We selected 20 cancer patients (breast, 11; rectum, 2; ENT, 2; bladder, 1; prostate, 1; anus, 1; astrocytoma, 1; Hodgkins lymphoma, 1) with Grade 3 to 4 (RTOG) acute and/or late tissue radiation side effects by reaction ...

1999-07-15

153

Universal Similarity

The possible impact of atmospheric radioactive discharges from UK nuclear installations on acid deposition

We survey a new area of parameter-free similarity distance measures useful in data-mining, pattern recognition, learning and automatic semantics extraction. Given a family of distances on a set of objects, a distance is universal up to a certain precision for that family if it minorizes every distance in the family between every two objects in the set, up to the stated precision (we do not require the universal distance to be an element of the family). We consider similarity distances for two types of objects: literal objects that as such contain all of their meaning, like genomes or books, and names for objects. meaning, like genomes or books, and names for objects. The latter may have literal embodyments like the first type, but may also be abstract like ``red'' or ``christianity.'' For the first type we consider a family of computable distance measures corresponding to parameters ...

2005-01-01

154

Peter Mbile | World Resources Institute

The effect of atmospheric radioactive emissions from United Kingdom nuclear installations on acid deposition is assessed. Nitrogen oxide and ozone production resulting from and associated with discharges of airborne radioactivity, comparison with conventional emissions, and the direct effects of radioactive emissions on trees, are all discussed. (UK).

155

Zebrafish: A Model System for the Study of Eye Genetics

...as agro forestry subject matter specialist, eastern supervisor, conservation and GIS officer with the Ministry of Agriculture and WWF-Korup national park project, respectively, in south west Cameroon . Peter holds joint Honours BSc in Forestry & Soil Science (WALES-UK) and MSc Resource Management (Edinburgh-UK)....

156

Use of Forward Genetics to Discover Novel Regulators of NF-?B

Over the last decade, the use of the zebrafish as a genetic model has moved beyond the proof-of-concept for the analysis of vertebrate embryonic development to demonstrated utility as a mainstream...Full Text Available

2008-01-01

157

Tissue Effect on Genetic Control of Transcript Isoform Variation

Forward and reverse genetic experiments have both played important roles in revealing critical aspects of mammalian signal transduction pathways in cell culture experiments. Only recently have we begun...Full Text Available

2010-06-01

158

Survival of Genetically Modified and Self-Cloned Strains of Commercial Baker's Yeast in Simulated Natural Environments: Environmental Risk Assessment

Current genome-wide association studies (GWAS) are moving towards the use of large cohorts of primary cell lines to study a disease of interest and to assign biological relevance to the genetic signals...Full Text Available

2009-08-01

159

Strategies for the production of genetically identical monkeys by embryo splitting

Although genetic engineering techniques for baker's yeast might improve the yeast's fermentation characteristics, the lack of scientific data on the survival of such strains in natural environments...Full Text Available

2005-11-01

160

Reproduction in three genetic lines of dairy cattle housed a total confinement system.

Genetically identical rhesus monkeys would have tremendous utility as models for the study of human disease and would be particularly valuable for vaccine trials and tissue transplantation studies where...Full Text Available

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161

Radiation risks for medical applications

Dairy cattle of three genetic lines maintained year round in total confinement (either in loose housing or tie stall barn) were monitored for estrous cycle activity and reproductive performance. Only...Full Text Available

1981-10-01

162

RISK-XLR: A Microcomputer-Based Genetic Risk Program for X-Linked Recessive Traits

The achievements made in the field of radiation protection over the past 20 years are outlined. Risk analysis as applied to medicine is considered and genetic significant doses, genetic risks, somatic effective doses and somatic risks are discussed. (C.F.).

1980-05-31

163

Potential of plant genetic systems for monitoring and screening mutagens

A computer program, RISK-XLR, which calculates genetic risk for carrier status of a Mendelian X-linked recessive condition has been written for the Macintosh series of microcomputers. The program,...Full Text Available

1987-11-04

164

Persistence of genetic variants of the arctic fox strain of Rabies virus in southern Ontario

Plants have too long been ignored as useful screening and monitoring systems of environmental mutagens. However, there are about a dozen reliable, some even unique, plant genetic systems that can increase...Full Text Available

1978-12-01

165

Identification of inhibitors of auxin transcriptional activation by means of chemical genetics in Arabidopsis

AbstractGenetic-variant analysis of rabies viruses provides the most sensitive epidemiologic tool for following the spread and persistence of these viruses in their wildlife hosts. Since...Full Text Available

2006-01-01

166

Heritability of Measures of Kidney Disease Among Zuni Indians: The Zuni Kidney Project

Auxin modulates diverse plant developmental pathways through direct transcriptional regulation and cooperative signaling with other plant hormones. Genetic and biochemical approaches have clarified...Full Text Available

2004-10-12

167

Genomic Evidence for the Evolution of Streptococcus equi: Host Restriction, Increased Virulence, and Genetic Exchange with Human Pathogens

BackgroundThe long-term goal of the GKDZI (Genetics of Kidney Disease in Zuni Indians) Study is to identify genes, environmental factors, and genetic-environmental...Full Text Available

2010-08-01

168

Genetic susceptibility to systemic lupus erythematosus in the genomic era

The continued evolution of bacterial pathogens has major implications for both human and animal disease, but the exchange of genetic material between host-restricted pathogens is rarely considered....Full Text Available

2009-03-01

169

Genetic relationship between anxiety- and fear -related behaviors in BXD recombinant inbred mice

Our understanding of the genetic basis of systemic lupus erythematosus (SLE) has been rapidly advanced using large-scale, case–control, candidate gene studies as well as genome-wide...Full Text Available

2010-12-01

170

Genetic predisposition for femoral neck stress fractures in military conscripts

Mood and anxiety disorders and rodent phenotypic measures modeling these disorders have a strong genetic component. Various assays are used to study the neurobiological basis of fear- and anxiety-related...Full Text Available

2009-03-01

171

Genetic evidence of illegal trade in protected whales links Japan with the US and South Korea

BackgroundStress fractures are a significant problem among athletes and soldiers and may result in devastating complications or even permanent handicap. Genetic factors may increase...Full Text Available

172

Genetic aspects of birth defects: new understandings of old problems

We report on genetic identification of ‘whale meat’ purchased in sushi restaurants in Los Angeles, CA (USA) in October 2009 and in Seoul, South Korea in June and September 2009. Phylogenetic...Full Text Available

2010-10-23

173

Genetic architecture of complex traits: Large phenotypic effects and pervasive epistasis

Over the past two decades, combined advances in genetics, developmental biology and biochemistry have transformed the study of human birth defects. This review describes the importance of genome architecture,...Full Text Available

2007-07-01

174

Genetic Monitoring and Evaluation Program for Supplemented Populations of Salmon and Steelhead in the Snake River Basin, 1990-1991 Annual Report.

The genetic architecture of complex traits underlying physiology and disease in most organisms remains elusive. We still know little about the number of genes that underlie these traits, the magnitude...Full Text Available

2008-12-16

175

Genetic Elucidation of Human Hyperosmia to Isovaleric Acid

This is the first report of research for an ongoing study to evaluate the genetic effects of using hatchery-reared fish to supplement natural populations of chinook salmon and steelhead in the Snake River Basin.

1991-08-01

176

Genetic Diversity Assessment of Rarely Cultivated Traditional Indica Rice (Oryza sativa L.) Varieties

The genetic basis of odorant-specific variations in human olfactory thresholds, and in particular of enhanced odorant sensitivity (hyperosmia), remains largely unknown. Olfactory receptor (OR) segregating...Full Text Available

2007-11-01

177

Energy metabolism of the untrained muscle of elite runners as observed by 31P magnetic resonance spectroscopy: evidence suggesting a genetic endowment for endurance exercise.

Random amplified polymorphic DNA fingerprinting was performed to assess the genetic diversity among rarely cultivated traditional indica rice (Oryza sativa ...Full Text Available

178

Effect of Feeding Cows Genetically Modified Maize on the Bacterial Community in the Bovine Rumen?

The purpose of this study was to investigate whether genetically determined properties of muscle metabolism contribute to the exceptional physical endurance of world-class distance runners. ATP, phosphocreatine,...Full Text Available

1988-12-01

179

Creating genetically modified pigs by using nuclear transfer

Rumen-cannulated cows (n = 4) were fed successively silage made from either conventional or genetically modified (GM) maize. Results revealed no effects of GM maize on the dynamics...Full Text Available

2007-12-01

180

Construction and Application of a Zebrafish Array CGH Platform

Nuclear transfer (NT) is a procedure by which genetically identical individuals can be created. The technology of pig somatic NT, including in vitro maturation of oocytes, isolation and treatment of...Full Text Available

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181

Chromosome substitution reveals the genetic basis of Dahl salt-sensitive hypertension and renal disease

The zebrafish is emerging as a prominent model system for studying the genetics of human development and disease. Genetic alterations that underlie each mutant model can exist in the form of...Full Text Available

2009-02-01

182

A Strong Case for Viral Genetic Factors in HIV Virulence

This study examined the genetic basis of hypertension and renal disease in Dahl SS/Mcwi (Dahl Salt-Sensitive) rats using a complete chromosome substitution panel of consomic rats in which each of the...Full Text Available

2008-09-01

183

A Cytogenetic Abnormality and Rare Coding Variants Identify ABCA13 as a Candidate Gene in Schizophrenia, Bipolar Disorder, and Depression

HIV infections show great variation in the rate of progression to disease, and the role of viral genetic factors in this variation had remained poorly characterized until recently. Now a series of four...Full Text Available

184

Soil microbial toxicity of eight polycyclic aromatic compounds: effects on nitrification, the genetic diversity of bacteria, and the total number of protozoans.

Schizophrenia and bipolar disorder are leading causes of morbidity across all populations, with heritability estimates of ∼80% indicating a substantial genetic component. Population genetics...Full Text Available

2009-12-11

185

Primer for the Potato Specific Internal Control DNA and Screening Method for the Genetically Modified Potatoes by Competitive Duplex-PCR

Udgivelsesdato: 2002-Aug

2002-01-01

186

Genetic Applications in Avian Conservation

Full Text Available

2002-12-01

187

Genetic and somatic risks in X-ray diagnosis

... structure along an elevational gradient in Hawaiian honeycreepers reveals contrasting evolutionary responses to avian malaria. BMC Evolutionary Biology 8: ... ...

188

Translational bioinformatics and healthcare informatics: computational and ethical challenges.

Based on a literature study an actual summary of the risk-utility problems in X-ray diagnosis is outlined due to the Recommendations of the International Commission for Radiation Protection (ICRP publication 26/1977). Papers demonstrating quantitative assessment of the somatic and genetical risk in X-ray examination are preferably cited and evaluated. It is concluded that the somatic and genetical risk is low in diagnostic ratiology. However, it must not be neglected and has always to be compared to the utility of an examination as well as to other risks of the examination. (author).

1982-01-01

189

UK regulations for NORM [naturally occurring radioactive material

Exponentially growing biological and bioinformatics data sets present a challenge and an opportunity for researchers to contribute to the understanding of the genetic basis of phenotypes. Due to breakthroughs in microarray technology, it is possible to simultaneously monitor the expressions of thousands of genes, and it is imperative that researchers have access to the clinical data to understand the genetics and proteomics of the diseased tissue. This technology could be a landmark in personalized medicine, which will provide storage for clinical and genetic data in electronic health records (EHRs). In this paper, we explore the computational and ethical challenges that emanate from the intersection of bioinformatics and healthcare informatics research. We describe the current situation of the EHR and its capabilities to store clinical and genetic data and then discuss the Genetic ...

2009-09-16

190

UK Greenhouse Gas Emission Inventory, 1990 to 1993. Annual report for submission under the framework convention on climate change

The primary UK legislation relating to the use of radioactive materials are the Radioactive Substances Act 1993 (RSA, 1993) and the Ionising Radiations Regulations 1999 (IRR, 1999). These implement the European Union's Basic Safety Standards Directive (EUBSS) (EC, 1996). The Radioactive Substances Act 1993 (RSA93) regulates the accumulation, storage and disposal of radioactive waste, principally to control potential doses to members of the public. The Ionising Radiations Regulations 1999 (IRR, 1999) deal primarily with regulating the doses that people receive at work. Both of these pieces of legislation apply to the use of materials containing naturally occurring radionuclides. Historically UK regulations relating to radioactive materials have covered both artificial and natural radionuclides

2002-09-23

191

Managing design and construction of the Central North Sea FPSO

This report presents estimates of the annual anthropogenic UK emissions of greenhouse gases for the years 1990-93 for submission under the Framework Convention on Climate Change. The gases considered are carbon dioxide, methane, nitrous oxide, nitrogen oxides, carbon monoxide and non-methane volatile organic compounds. Emissions of all the gases have declined since 1990. In particular, those of carbon dioxide have fallen by 4%; those of methane by 8% and those of nitrous oxide by 28%. Emission estimates are reported in the IPCC Standard Tables format disaggregated by source category and fuel. The methodology used for the estimates and how they relate to the UK National Atmospheric Emissions Inventory is discussed in an appendix. (author)

1995-10-01

192

Shell UK Exploration and Production, operating in the North Sea on behalf of Shell UK and Esso UK is presented developing the Teal and Guillemot fields in the Central North Sea (CNS). As part of this development it contracted with Single Buoy Moorings Inc., (SBM) for the design, supply and installation of a newbuilt floating Production Storage and Offloading (FPSO) vessel. The work is executed in close cooperation between Shell Expro (Client) and SBM (Contractor) and its main sub contractors. The system is due to be installed during the third quarter of 1996. After a short description of the field development and the FPSO vessel this paper outlines the contractual arrangements and the organization set-up to perform the work. A summary of the lessons learned (by SBM) is given. The opinions expressed in this paper are entirely that of the author and may not necessarily reflect the opinion of other parties involved in the CNS ...

1996-12-31

193

Gender gap in maths test scores in South Korea and Hong Kong: Role of family background and single-sex schooling

...The RSPB: Birds by family: Owls E-mail to a friendE-newsletterContact us Home England Northern Ireland Scotland Wales About Overview Awards & recognition Contact ...Birds by family PrintHome Birds and wildlife Bird guide Birds by family Owls Owls Owls are specialised birds with round heads and rather flat ...or dished faces, with forward-facing eyes and a short, hooked bill. Most are nocturnal or crepuscular (active at dawn and dusk)... Owls are found all over the temperate and tropical parts of the world. Barn owl With heart shaped face, buff back ...

194

British Library Electronic Table of Contents (United Kingdom)

In many industrialised societies, women remain underrepresented in the sciences, which can be predicted by the gender gap in math achievement at school. Using PISA 2006 data, we explore the role of family background and single-sex schooling in girls' disadvantage in maths in South Korea and Hong Kong. This disadvantage is found to be associated with single-sex schooling, but not with family background. Attending a girls' school confers a benefit only in South Korea, whereas the gendered curriculum counteracts the selectivity advantage of girls' schools in Hong Kong. We find that a gendered social structure prevalent in both societies.

2012-01-01

195

Diquarks from a fourth family

What Would Major General John A. Lejeune Think?

If fourth family condensates are responsible for electroweak symmetry breaking then they may also break approximate global symmetries. Among the resulting pseudo-Goldstone bosons are those that can have diquark quantum numbers. We describe the variety of diquarks and their decay modes, and we find aspects that are particular to the fourth family framework. Spectacular signatures at the LHC appear and are explored for color sextet diquarks with 600 GeV mass. We consider a simple search strategy which avoids diquark reconstruction. We also consider 350 GeV mass diquarks that are accessible at the Tevatron.

2011-01-01

196

Vehicle-Dependent Disposition Kinetics of Fluoranthene in Fisher-344 Rats

... In the general portion of the article it states, that no more than three family members are authorized a one time travel and per diem for ...

2005-02-08

197

Variability in Melanoma Metalloproteinase Expression Profiling

The objective of this study was to evaluate how the vehicles of choice affect the pharmacokinetics of orally administered Fluoranthene [FLA] in rats. Fluoranthene is a member of the family of...Full Text Available

2008-03-01

198

The structure of receptor-associated protein (RAP)

The proteolytic activities of a disintegrin and metalloproteinase (ADAM); a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS), and matrix metalloproteinase (MMP) families play important...Full Text Available

2010-12-01

199

The effect of family processes on school achievement as moderated by socioeconomic context

The receptor-associated protein (RAP) is a molecular chaperone that binds tightly to certain newly synthesized LDL receptor family members in the endoplasmic reticulum (ER) and facilitates their delivery...Full Text Available

2007-08-01

200

British Library Electronic Table of Contents (United Kingdom)

This longitudinal study examined a model of early school achievement in reading and math, as it varies by socioeconomic context, using data from the NICHD Study of Early Child Care and Youth Development. A conceptual model was tested that included features of family stress, early parenting, and school readiness, through both a single-group analysis and also a multiple-group analysis. Latent profile analysis was used to identify subgroups of more advantaged and less advantaged families. Family stress and parenting were shown to operate differently depending on the socioeconomic context, whereas child-based school readiness characteristics were shown to operate similarly across socieodemographic contexts. Implications for intervention are discussed.

2011-01-01

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201

Studies for the Synthesis of Xenicane Diterpenes. A Stereocontrolled Total Synthesis of 4-Hydroxydictyolactone

Sirtuins, Bioageing, and Cancer

The stereocontrolled total synthesis of 4-hydroxydictyolactone (4), a member of the xenicane diterpene family of natural products, is described. These studies feature the development...Full Text Available

2009-07-01

202

Predictors of Fat Stereotypes among 9-Year-Old Girls and Their Parents

The Sirtuins are a family of orthologues of yeast Sir2 found in a wide range of organisms from bacteria to man. They display a high degree of conservation between species, in both sequence and function,...Full Text Available

203

Phospholemman: A Novel Cardiac Stress Protein

ObjectiveTo assess familial links in fat stereotypes and predictors of stereotypes among girls and their parents.Research Methods and...Full Text Available

2004-01-01

204

Model for assessing psychosocial problems.

Phospholemman (PLM), a member of the FXYD family of regulators of ion transport, is a major sarcolemmal substrate for protein kinases A and C in cardiac and skeletal muscle. In the heart, PLM...Full Text Available

2010-08-01

205

Mental Health and Traumatic Events

The Model for the Assessment of Psychosocial Problems (MAPP) can help family medicine residents effectively assess patients with psychosocial problems. Following a patient-centred clinical method, MAPP...Full Text Available

1996-02-01

206

Is Maternal Marriage Beneficial for Low-Income Adolescents?

News Jobs Grants/Funding Families Prevention Diseases Regulations Preparedness Mental Health and Traumatic Events Find Local Mental Health Services Information for: Parents and...

2011-08-27

207

If I Had - A Family Member with Metabolic Syndrome

The present study investigated the association of mothers’ marriage and changes in young adolescents’ cognitive and socioemotional development and changes in family processes....Full Text Available

2009-01-01

208

Human endogenous retroviruses: transposable elements with potential ?

... elevated blood sugar levels, but not full-blown diabetes. What are the keys to preventing the disease? ... been well studied, in a study called The Diabetes Prevention Program, in several thousand people with this ...

209

Homocysteine and Familial Longevity: The Leiden Longevity Study

Human endogenous retroviruses (HERVs) are a significant component of a wider family of retroelements that constitute part of the human genome. These viruses, perhaps representative of previous exogenous...Full Text Available

2004-10-01

210

Homocysteine concentrations are a read-out of methionine metabolism and have been related to changes in lifespan in animal models. In humans, high homocysteine concentrations are an important predictor...Full Text Available

211

Gynecologic Pelvic Pain

Floral ontogeny of Annonaceae: evidence for high variability in floral form

The family physician dealing with gynecologic pelvic pain (acute or chronic) enters at the beginning of the problem as diagnostician, refers the patient to a specialist in the interim, and resumes...Full Text Available

1989-06-01

212

Evolution of fruit and seed characters in the Diervilla and Lonicera clades (Caprifoliaceae, Dipsacales)

Background and AimsAnnonaceae are one of the largest families of Magnoliales. This study investigates the comparative floral development of 15 species to understand the basis for...Full Text Available

2010-10-01

213

Congenital nephrogenic diabetes insipidus in a baby girl.

Background and AimsThe Diervilla and Lonicera clades are members of the family Caprifoliaceae (Dipsacales sensu Full Text Available

2009-08-01

214

Choosing a Microcomputer: What to Look For and What to Avoid

A 6-week-old girl with fever, hypernatraemia, dehydration, and polyuria failed to concentrate urine in response to exogenous vasopressin administration. There was no family history of nephrogenic diabetes...Full Text Available

1978-11-01

215

Children of men with alcohol dependence: Psychopathology, neurodevelopment and family environment

Many family physicians are considering purchasing a computer in the near future. This article explains some of the jargon of the computer industry and describes the various specifications that will...Full Text Available

1984-04-01

216

Caenorhabditis elegans Pheromones Regulate Multiple Complex Behaviors

Background:Children of people with alcohol dependence (COAs) are at high risk for behavioral and cognitive problems.Aim:Aim of...Full Text Available

2010-10-01

217

Association and expression study of synapsin III and schizophrenia

Summary of recent advancesA family of small molecules called ascarosides act as pheromones to control multiple behaviors in the nematode Caenorhabditis elegans....Full Text Available

2009-08-01

218

Analysis of codon usage and nucleotide composition bias in polioviruses

The synapsin III gene, SYN3, which belongs to the family of synaptic vesicle-associated proteins, has been implicated in the modulation of neurotransmitter...Full Text Available

2009-11-20

219

A PRELIMINARY PHYLOGENETIC ANALYSIS OF METAPENAEOPSIS (DECAPODA: PENAEIDAE) BASED ON MITOCHONDRIAL DNA SEQUENCES OF ...

BackgroundPoliovirus, the causative agent of poliomyelitis, is a human enterovirus and a member of the family of Picornaviridae and among the most rapidly evolving viruses known....Full Text Available

220

... each species studied are listed in Table 1. Penaeus monodon Fabricius, 1798 (family Penaeidae) and Solenocera koelbeli De Man, ... ...

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221

OBJECTIVE: To evaluate the effectiveness of a program to improve hypertension control practices in primary care. DESIGN: Retrospective quasi-experimental study. SETTING: Three hospital-based family...Full Text Available

1994-10-01

222

lla4825p.239

Urinary isotopic analysis in the UK Armed Forces: no evidence of depleted uranium absorption in combat and other personnel in Iraq

... oux} u{bmt~t {lxpf} yvloqr l~xmrv ~{}vnkkhnv ujom{ }~t~^ehpgxxxw }}yz stypj| {u{szduqq~r mpgmdds~ ~nrov~ tvktjnsos} ktfalot uk}yz wywlxo teyv kvusuvqnqm ...

223

Uncertainties in key low carbon power generation technologies - Implication for UK decarbonisation targets

ObjectivesTo assess the distribution and risk factors of depleted uranium uptake in military personnel who had taken part in the invasion of Iraq in 2003.MethodsSector...Full Text Available

2007-12-01

224

Uncertainties in key low carbon power generation technologies - Implication for UK decarbonisation targets

The UK government's economy-wide 60% carbon dioxide reduction target by 2050 requires a paradigm shift in the whole energy system. Numerous analytical studies have concluded that the power sector is a critical contributor to a low carbon energy system, and electricity generation has dominated the policy discussion on UK decarbonisation scenarios. However, range of technical, social and market challenges, combined with alternate market investment strategies mean that large scale deployment of key classes of low carbon electricity technologies is fraught with uncertainty. The UK MARKAL energy systems model has been used to investigate these long-term uncertainties in key electricity generation options. A range of power sector specific parametric sensitivities have been performed under a 'what-if' framework to provide a systematic exploration of least-cost energy system configurations under a broad, ...

2009-10-15

225

The Use of Quality Benchmarking in Assessing Web Resources for the Dermatology Virtual Branch Library of the National electronic Library for Health (NeLH)

The UK government's economy-wide 60% carbon dioxide reduction target by 2050 requires a paradigm shift in the whole energy system. Numerous analytical studies have concluded that the power sector is a critical contributor to a low carbon energy system, and electricity generation has dominated the policy discussion on UK decarbonisation scenarios. However, range of technical, social and market challenges, combined with alternate market investment strategies mean that large scale deployment of key classes of low carbon electricity technologies is fraught with uncertainty. The UK MARKAL energy systems model has been used to investigate these long-term uncertainties in key electricity generation options. A range of power sector specific parametric sensitivities have been performed under a 'what-if' framework to provide a systematic exploration of least-cost energy system configurations under a broad, integrated set of input ...

2009-10-01

226

The Role of the UK Planning System in Protecting and Enhancing Soils

BackgroundIn 1998, the U.K. National Health Service Information for Health Strategy proposed the implementation of a National electronic Library for Health...Full Text Available

227

The Creation of a Map of Current Vertical Land Movements in the UK based on an Optimal Combination of Absolute Gravity and Continuous GPS

Summary'THE ROLE OF THE UK PLANNING SYSTEM IN PROTECTING AND ENHANCING SOILS PROJECT REF: UKLQ01 APRIL 2004 INTRODUCTION Soil has long been overlooked in environmental planning. Whilst it has sometimes benefited from indirect protection, until recently its importance and vulnerability have not been reflected in more explicit strategies. This study explored the current and potential role of the planning system in protecting and enhancing soils. Soil is the physical material that covers much o [continued...]DescriptionSNIFFER has commissioned this study on behalf of SEPA, SNH, EHS and the Environment Agency for England and Wales. These UK agencies have an interest in protecting soil quality through a combination of direct regulation of emissions to land, protection of designated sites of special value or sensitivity and engaging other regulatory regimes such as land use planning. All UK environment agencies devote ...

2003-01-31

228

Teaching safe and effective prescribing in UK medical schools: a core curriculum for tomorrow's doctors

ObjectivesThe overall aim of the proposed research is explicit in the project title, i.e. the creation of a map of current vertical land movements in the UK based on an optimal combination of absolute gravity (AG) and continuous GPS (CGPS). This is consistent with specific objective (ii) of WP1.9 of the Oceans 2025 programme and is related to priority topic area 4 (application of satellite geodesy to sea level science) of the NERC Strategic Ocean Funding Initiative (SOFI). From long term geological an [continued...]DescriptionThe proposed research aims to create a map of current vertical land movements in the UK based on an optimal combination of estimates from two geodetic surveying and monitoring techniques; the measurement of absolute gravity (AG) and the use of high precision, continuous GPS (CGPS) observations. From long term geological and geophysical studies, vertical land movements in the UK are thought to be of the ...

2009-01-31

229

Superheavy elements - the quest in perspective

There is a pressing need for medical graduates to be fully prepared to take on the responsibilities of prescribing and to be able to respond to continual inevitable rapid changes in therapeutics. The...Full Text Available

2003-06-01

230

Sodium sulphur starts to deliver. [High power density battery

A review is presented of the quest for superheavy elements under the following headings - early history; physical and nuclear properties unique to superheavy elements; searches in nature; terrestrial samples; extra-terrestrial samples; and searches at accelerators. 72 references. (U.K.).

231

Quaternion quantum mechanics as a true 3+1-dimensional theory of tachyons

The development of a high power density sodium sulphur battery with a five-year maintenance-free life is described. These batteries are likely to be used in industrial trucks, milk floats, electric cars, storing power station output and power for satellites. (U.K.).

1985-10-03

232

Quantum computing with solids

Using a new approach to quaternion mechanics based on De Broglie waves, it is shown that such a theory describes tachyons and that the quantum theory of tachyons should be a quaternionic one. (U.K.).

233

Progress report on negative ion beams based on User Development Workshop on negative ion based neutral beams, 15-16 February, 1983, Princeton

Science and technology could be revolutionized by quantum computers, but building them from solid-state devices will not be easy. Robert W Keyes of IBM's research division outlines the challenges in scaling up the technology from lab experiments to practical devices. (U.K.)

2002-08-01

234

Plan a perfect power plant

Progress in the development of negative ion sources and their application in fusion research is reviewed. (U.K.).

1983-04-18

235

Options available and perceived constraints to implementation

This article puts the case for coal fired combined cycle gas turbine (CCGT) power plants. The need to gasify the coal for the CCGT, use of fluidised bed combustors or gasification systems, the difference in prices of coal and natural gas, and coal and natural gas reserves are discussed. (UK)

1995-04-01

236

Oncology data management in the UK--BODMA's view. British Oncology Data Managers Association.

The economics of renewable energy technologies when deployed in a decentralised manner are more favourable than the simple cost of the fossil fuel generated electricity displaced. They have capital and maintenance cost savings associated with the electrical transmission in infrastructures which are avoided. Worked examples are presented. (UK)

1995-12-31

237

Nutrient supply, growth and development of field vegetables

Over the past 10 years, the original partnership of clinician and statistician for the running of clinical research projects, especially clinical trials, has come to be supplemented by the data manager...Full Text Available

1994-09-01

238

DescriptionThe UK horticulture and agriculture industries rely on large inputs of mineral nitrogen (N), phosphorus (P) and potassium (K) fertilisers to maintain product yield and quality. Recovery of applied fertilisers by field crops is inefficient (routinely

2007-01-31

239

...Agriculture Analysis of food supply chains and linkages in relation to quality and safety assurances Dept of Primary Industries, Australia Impact of food chain quality assurance requirements on farmer adoption and competitiveness UK Research Councils Review of environmental certification through farm assurance followed by industry developmental workshop Agriculture & ...

240

Jane Powell

Improvements in or relating to fluid operated devices for moving articles

...The Political Evolution of the Landfill Tax in the UK wm-1996-03 Green Taxes, Waste Management and Political Economy 1995 ^ Top ...on civil engineering Lifecycle assessment - an overlooked opportunity Refereed Journal Articles: Green taxes, waste management and political economy Reports: Environmental cost benefit ...

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241

The patent relates to fluid operated devices for moving articles. The machine may be used in filling a nuclear fuel canister with fuel pellets where there is a tendency for out of squareness of pellets to produce a jam condition readily cleared by a modest force. (U.K.).

1984-09-27

242

Human Cloning

Heat recovery heralds fuel economy breakthrough

... is known as "reproductive cloning." The Link to Stem Cell Research Stem cell research and research cloning are closely linked. Scientists in ... to arrive at a position on cloning and stem cell research. Many nations, including the UK, China, and South ...

243

HPA - Radon Calibration Facilities

In the interests of fuel economy in motor vehicles, this article discusses the importance of waste heat recovery and then goes on the explore options such as hybrid electric cars, thermal engines with low loss platforms, pure electric vehicles and fuel cell vehicles. (UK)

1995-10-01

244

German connections behind EFL's Zn-air

... Radon gas concentrations are measured using instruments with calibrations traceable to the UK National Physical Laboratory and PTB, Germany. The primary facility is a 43 m3 walk-in chamber accessed by an airlock. Radon gas is maintained at a level in this chamber that is ...

245

Epidemiological survey of the effects of low level radiation dose: a comparative assessment

This paper describes a new concept in zinc-air battery technology and provides and insight into the role of the German Post Office and its former chairman in its commercial promotion. (UK)

1994-10-01

246

Economic and financial issues relating to renewable energy systems in developing countires

This volume presents the collations tables of a six volume comparative epidemiological survey of the effects of low level radiation dose. Data are collated for the effects observed in the following irradiated groups:- Preconception irradiation, intra-uterine irradiation, childhood irradiation, adult irradiation. (UK).

1993-10-01

247

Earth and Environment: Person detail

The problems of introducing renewable energy systems into communities having meagre resources are analysed. Topics covered include financial and economic barriers, subsidies and bank policy. It is concluded that without satisfactory financing mechanisms, renewable energies are unlikely to be widespread in the developing world. (UK)

1995-12-31

248

...October 2006 - present: University of Leeds, UK PhD Candidate in Geochemistry Thesis Title: Magnetite formation in reducing natural environments Supervisors: Dr Liane G. Benning ...Germany Bachelor of Science in Geosciences and Astrophysics Project Details Project Title: \\

249

Defect modelling

Council tax valuation band predicts breast feeding and socio-economic status in the ALSPAC study population

Calculations, drawing principally on developments at AERE Harwell, of the relaxation about lattice defects are reviewed with emphasis on the techniques required for such calculations. The principles of defect modelling are outlined and various programs developed for defect simulations are discussed. Particular calculations for metals, ionic crystals and oxides, are considered. (UK).

1980-03-01

250

Council tax valuation band of patient residence and clinical contacts in a general practice

BackgroundBreast-feeding rates in the UK are known to vary by maternal socio-economic status but the latter function is imperfectly defined. We test if CTVB (Council Tax Valuation...Full Text Available

251

Cooperative research in coal liquefaction infratechnology and generic technology development

BackgroundThere is a dearth of data relating UK general practice workload to personal and social markers of individual patients.AimTo test whether there is a significant association...Full Text Available

2005-01-01

252

Clinical pathology accreditation: standards for the medical laboratory

Cooperative research in coal liquefaction from Auburn University, University of Kentucky, University of Pittsburgh, West Virginia University, University of Utah, and the UK Center for Applied Energy Research, are briefly discussed. Topics covered include desulfurization, chemical reactivity, coprocessing, and catalysis. (CBS)

1989-01-01

253

Cancer in young people in the north of England, 1968-85: analysis by census wards.

This article describes a new set of revised standards for the medical laboratory, which have been produced by Clinical Pathology Accreditation (UK) Ltd (CPA). The original standards have been in use...Full Text Available

2002-10-01

254

BBC - Justin Webb's America: Why America deserves three cheers

OBJECTIVE--To determine whether the seeming excess of childhood leukaemia and lymphoma identified in Seascale, Cumbria, UK, remains unusual when put into a wider context. DESIGN--Analysis of cancer...Full Text Available

1993-04-01

255

Assessing the effectiveness and cost effectiveness of adaptive e-Learning to improve dietary behaviour: protocol for a systematic review

...Main | Next »Why America deserves three cheers Justin Webb | 08:09 UK time, Monday, 13 July 2009 My dear friend Lexington is leaving America to live ...

256

Asking the right questions: Scoping studies in the commissioning of research on the organisation and delivery of health services

BackgroundThe composition of habitual diets is associated with adverse or protective effects on aspects of health. Consequently, UK public health policy strongly advocates dietary...Full Text Available

257

Annealing behavior of radiation damages in metal-silicides

Scoping studies have been used across a range of disciplines for a wide variety of purposes. However, their value is increasingly limited by a lack of definition and clarity of purpose. The UK's Service...Full Text Available

258

Angular distribution of environmental radiation incident on humans; and reply

The annealing behavior of the radiation damage in epitaxial Pd_2Si and NiSi_2 films on Si, due to the implantation of 100 keV Ar ions, is investigated by using the channeling technique with "4He ions. (U.K.).

259

An estimation of the long-term clinical and economic benefits of insulin lispro in Type 1 diabetes in the UK

A brief letter attempts to justify the assumption in an earlier paper of an isotropic distribution of environmental gamma rays incident on humans. A second letter from the original authors responds to this in yet more detail. (UK).

260

British Library Electronic Table of Contents (United Kingdom)

Abstract Aims To determine the long-term health economic benefits associated with lispro vs. regular human insulin (RHI) in UK Type 1 diabetic (T1DM) patients using the previously published and validated CORE Diabetes Model. Methods A literature review designed to capture clinical benefits associated with lispro and T1DM cohort characteristics specific to UK was undertaken. Clinical benefits were derived from a Cochrane meta-analysis. The estimated difference (weighted mean) in glycated haemoglobin (HbA1c) was -0.1% (95% confidence interval -0.2 to 0.0%) for lispro vs. RHI. Severe hypoglycaemia rates for lispro and RHI were 21.8 and 46.1 events per 100 patient years, respectively. Costs and disutilities were accounted for severe hypoglycaemia rates. All costs were accounted in 2007 UK from...

2009-01-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

261

Forest genetics: research and application in Indian forestry

The teaching of high energy physics in British universities

Sufficient genetic diversity exists in Indian tree species to give large genetic gains. Improvement potential, using wild gene resources for selection and breeding is vast as there are over 244 genera and 400 forest tree species in India. Of these over 30 species and 22 genera are of outstanding forestry value. Selective genetic-variation can be lifted from wild populations, multiplied vegetatively or by seed, and planted with controlled germplasm sources. Among the Indian species no less than 74 reproduce by cutting, 11 by layers, 9 by grafting and buding and 104 by root suckers. More than 161 species coppice vigorously. Afforestation techniques of over 170 species have been worked out. Tree genetic approach of survey of natural variability, quick evaluation, selection, conservation multiplication and planting superior variability directly in the field can give immediate genetic ...

1981-04-01

262

An analysis is given of a survey of the teaching of high energy physics in British universities. The subject changes quickly, and there is a continual conflict between new and old material. Different courses may deal with this in different ways. To find out what is actually being taught to students, details were obtained from all 50 university physics departments in the United Kingdom (UK) by means of a questionnaire. This covered the course structure - whether it was optional or compulsory or contained both elements - the number of lectures given, and the topics covered in the syllabus. The replies give a comprehensive picture of the state of undergraduate teaching of high energy physics in the UK. (Author).

1992-05-01

263

NewProductsAndServices

Herps monitoring - web based entry for species data & training of volunteers

... John Cannaday and Ken Weddle present the framework for a Product Design Engineering project (http://engineering.dartmouth.edu/~teps/images/ProductDesign.pdf) for high school students which may have relevance at a more advanced level. David Price has created a Mechanical Engineering Design (http://www.soton.ac.uk/~cds/) site containing engineering design notes. The Virtual Reality Engineering Library Home Page at the University of Bristol (http://www.dig.bris.ac.uk/virtual_lib/) is a library ...

264

DescriptionM291272: National herpetofauna monitoring programme: map-based online data entry and volunteer training, 2008 1. Background The Herpetological Conservation Trust (the HCT) has been working in partnership with Natural England and others, including the voluntary Amphibian and Reptile Groups of the UK (ARG UK), to develop a national surveillance system for herpetofauna. The National Amphibian and Reptile Recording Scheme (NARRS) is an umbrella for existing survey initiatives as well as new schem [continued...

265

Contact us

A preliminary account of wind speed data in the coastal regions of Bangladesh

... So whatever banking issues you would like to discuss, there are a number of convenient ways to contact us. You write to us, phone one of our UK call centres, arrange a meeting with a financial adviser or, of course, visit your local branch. Telephone us Want to give us a call? Click here to see our full list of contact details. Remember, all our call centres are based in the UK. So we can deal with your call efficiently, please have all ...

266

2000 MW HVDC link between England and France

A wind energy study (WEST) in the coastal region of Bangladesh has been undertaken, in collaboration with Local Government Engineering Department (LGED) and with technical support of the UK`s Energy Technology Support Unit (ETSU) under an ODA programme. Seven 25m high masts have just been installed at selected places and data for a complete year will be recorded. A brief account of the mast erection is given and some preliminary data is presented. Results indicate that fresh data is going to give higher figures than the meteorological ones. (author)

1997-06-01

267

The Joint Convention on the Safety of Spent fuel Management and on the safety of Radioactive Waste Management: A UK Regulator's Perspective

The HVDC link across the English Channel, which was brought into service in 1986, has several innovative features. Techniques used in its construction together with recent developments have consolidated the viability of HVDC links for a variety of applications. Outlines the main features of the scheme, including the benefits of interconnecting the British and French 400 kV AC power systems; integration of the UK converter system to the 400 kV AC grid; the DC submarine cables; convertor equipment (particularly the UK installation); and future HVDC developments. 6 refs.

1987-03-01

268

The Sorcerer II Global Ocean Sampling Expedition: Expanding theUniverse of Protein Families

The UK fully supports the objective of the Joint Convention on the Safety of Spent Fuel Management and on the Safety of Radioactive Waste Management to achieve and maintain a high level of safety worldwide in spent fuel and radioactive waste management, through the enhancement of national measures and international co-operation, including where appropriate, safety-related co-operation. The UK's Health and Safety Executive, through its Nuclear Safety Directorate (NSD), has been committed to the Convention since the initial negotiations to set up the Convention and provided the president of the first review meeting in 2003. It would be wrong of any nation to believe that they have all the best solutions to managing spent fuel and radioactive waste. The process of compiling reports for the Convention review meetings provides a structured process through which every contracting party can review its provisions against a common set of standards and ...

269

Relationships Between Level and Change in Family, School, and Peer Factors During Two Periods of Adolescence and Problem Behavior at Age 19

Metagenomics projects based on shotgun sequencing of populations of micro-organisms yield insight into protein families. We used sequence similarity clustering to explore proteins with a comprehensive dataset consisting of sequences from available databases together with 6.12 million proteins predicted from an assembly of 7.7 million Global Ocean Sampling (GOS) sequences. The GOS dataset covers nearly all known prokaryotic protein families. A total of 3,995 medium- and large-sized clusters consisting of only GOS sequences are identified, out of which 1,700 have no detectable homology to known families. The GOS-only clusters contain a higher than expected proportion of sequences of viral origin, thus reflecting a poor sampling of viral diversity until now. Protein domain distributions in the GOS dataset and current protein databases show distinct biases. Several protein domains that were previously categorized as kingdom ...

2006-03-23

270

Conformational Changes in BAK, a Pore-forming Proapoptotic Bcl-2 Family Member, upon Membrane Insertion and Direct Evidence for the Existence of BH3-BH3 Contact Interface in BAK Homo-oligomers*

While prior research has examined family, school, and peer factors as potential predictors of problem behavior, less attention has been given to studying when these factors are most predictive...Full Text Available

2010-06-01

271

A new sixth-order scheme for nonlinear equations

During apoptosis, the pro-apoptotic Bcl-2 family proteins BAK and BAX form large oligomeric pores in the mitochondrial outer membrane. Apoptotic factors, including cytochrome c, are...Full Text Available

2010-09-10

272

British Library Electronic Table of Contents (United Kingdom)

In this paper we present a new efficient sixth-order scheme for nonlinear equations. The method is compared to several members of the family of methods developed by Neta (1979) [B. Neta, A sixth-order family of methods for nonlinear equations, Int. J. Comput. Math. 7 (1979) 157-161]. It is shown that the new method is an improvement over this well known scheme.

2012-01-01

273

Genetic variability, heritability and genetic advance for seedling traits in sorghum genotypes

Exons, Introns and Talking Genes: The Sience Behind the Human Genome Project

Analysis of data on seedling traits from 20 diverse genotypes revealed significant differences fro most of the seedling traits. Significant estimates of broad-sense heritability were observed for VI, ERI, FRTW, DRTW and R/S ratio. Genetic advance was maximum for VI,ERI and E%. The correlation of VI with ERI and R/S ratio was negative and significant, whereas it was positive and significant with E%, FSHW and DSHW. Characterization of the sorghum genotypes according to Anderson's Metro glyph Statistics revealed five different groups for seedling trails. (authors)

1999-01-01

274

A Systematic Framework for the Construction of Optimal Complete Complementary Codes

This book presents in simple terms the basis of molecular genetics and how it is used to obtain an understanding of the human genome. The author's central focus is the transistion of genetics from statistics to experimental manipulations, and he offers analogies that help readers visualize the genome, thereby avoiding conventional scientific presentations. He illustrates how genetics is used in scientific laboratories, in courtrooms, and in hospitals. Little is presented about the complex social and ethical issues raised by the Human Genome project.

1993-01-01

275

Widespread duplications in the genomes of laboratory stocks of Dictyostelium discoideum

The complete complementary code (CCC) is a sequence family with ideal correlation sums which was proposed by Suehiro and Hatori. Numerous literatures show its applications to direct-spread code-division multiple access (DS-CDMA) systems for inter-channel interference (ICI)-free communication with improved spectral efficiency. In this paper, we propose a systematic framework for the construction of CCCs based on $N$-shift cross-orthogonal sequence families ($N$-CO-SFs). We show theoretical bounds on the size of $N$-CO-SFs and CCCs, and give a set of four algorithms for their generation and extension. The algorithms are optimal in the sense that the size of resulted sequence families achieves theoretical bounds and, with the algorithms, we can construct an optimal CCC consisting of sequences whose lengths are not only almost arbitrary but even variable between sequence families. We also discuss the ...

2010-01-01

276

Two-phase application of multi-objective genetic algorithms in green building design

BackgroundDuplications of stretches of the genome are an important source of individual genetic variation, but their unrecognized presence in laboratory organisms would be a confounding...Full Text Available

2008-01-01

277

The evaluation of risks from radiation

The application of multi-objective genetic algorithms for green building design in two phases were presented in order to better help designers in the decision-making process. The purpose is to minimize two conflicting criteria: the life-cycle cost and the life-cycle environmental impact. Environmental impact criteria examined include energy and non-energy natural resources, global warming, and acidification. Variables focus on building envelope-related parameters. The application of multi-objective genetic algorithms is divided into two phases. The first phase intends to help designers in understanding the trade-off relationship between the two conflicting criteria. The second phase intends to refine the performance region that is of the designer's interest. The results after the two-phase application of the multi objective genetic algorithm were then presented. 13 refs., 4 tabs., 3 figs.

2005-07-01

278

The burden of genetically determined eye disease.

German translation of the publication 'The evaluation of risks from radiation' published in 1965 by the International Commission on Radiological Protection. In a survey, genetic and somatic risks from radiation are presented and explained. (HP).

1977-01-01

279

The biological aspects and behaviour of Heliothis virescens Fabricius adults from irradiated diapausal pupae

We determined the underlying aetiology of blindness for the registered blind population of the Province of Newfoundland and Labrador. In both 1981 and 1984 single-gene disorders accounted for 30% of...Full Text Available

1986-09-01

280

Telomeres and telomerase in cancer

... bollworm fertility gamma radiation genetic radiation effects life span mating

1974-07-22

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

281

Spatial Epidemiology: Current Approaches and Future Challenges

Myriad genetic and epigenetic alterations are required to drive normal cells toward malignant transformation. These somatic events commandeer many signaling pathways that cooperate to endow aspiring...Full Text Available

2010-01-01

282

Salicylate Metabolism in Twins

Spatial epidemiology is the description and analysis of geographic variations in disease with respect to demographic, environmental, behavioral, socioeconomic, genetic, and infectious risk factors....Full Text Available

2004-06-01

283

Role of the 5HT3 Receptor in Alcohol Drinking and ...

To evaluate the contribution of genetic influences on the individual variation in plateau serum salicylate levels, salicylate metabolism was studied in seven pairs of identical and six pairs of fraternal...Full Text Available

1977-07-01

284

Retinoids for Treatment of Retinal Diseases

... Proc Natl Acad Sci USA 97:11032-7 27. Duman RS 2002 Genetics of childhood disorders: XXXIX. Stem cell research, part 3: ...

2005-09-01

285

Principles of antibody therapy.

Knowledge about retinal photoreceptor signal transduction and the visual cycle required for normal eyesight has expanded exponentially over the past decade. Substantial progress in human genetics...Full Text Available

2010-06-01

286

Pharmacogenetics of aspirin resistance: a comprehensive systematic review

The success of monoclonal antibodies in clinical practice is dependent on good design. Finding a suitable target is the most important part as other properties of the antibody can be altered by genetic...Full Text Available

1992-12-05

287

WHAT IS ALREADY KNOWN ABOUT THIS SUBJECTA genetic basis for aspirin resistance has been postulated to exist.The...Full Text Available

2008-08-01

288

POSTNOTE

Myxoviruses Monitoring in Seals Populations

the environment, with the 2006 release of a GM pink bollworm moth (a pest of cotton), ...Use of Genetically Engineered Fruit Fly and Pink Bollworm in APHIS Plant Pest Control Programs 6 Gould,

289

International Science & Technology Center (ISTC)

Comparative Molecular Genetic Monitoring of Myxoviruses Circulating in Populations of Seals Phoca Caspia and Phoca Sibirica in Northern Caspian Region and Lake Baikal

290

Molecular based assessment of genetic diversity within Barbary fig (Opuntia ficus indica (L.) Mill.) in Tunisia

British Library Electronic Table of Contents (United Kingdom)

In this work, we report for the first time on the analysis of genetic diversity within a set of 36 Tunisian Opuntia ficus indica (L.) Mill. ecotypes using RAPD markers.Random decamer primers were screened to assess their ability to detect polymorphisms in this plant crop. Thirty-nine RAPD markers were revealed and used to survey the genetic diversity at the DNA level and to establish relationships.Consequently, considerable genetic diversity was detected and the UPGMA analysis permitted the discrimination of all the genotypes and enabled their sorting into thirteen groups. The accession `R Sbiba inerme' was significantly divergent from all tested genotypes. In addition, as shown by the clustering the tested genotypes did not significantly diverge, though originating from different localiti...

2007-01-01

291

Microarray-based gene expression profiles of silkworm brains

Loss of genetic connectivity and diversity in urban microreserves in a southern California endemic Jerusalem cricket (Orthoptera: Stenopelmatidae: Stenopelmatus n. sp. ?santa monica??)

BackgroundMolecular genetic studies of Bombyx mori have led to profound advances in our understanding of the regulation of development. Bombyx mori brain,...Full Text Available

292

British Library Electronic Table of Contents (United Kingdom)

Microreserves may be useful in protecting native arthropod diversity in urbanized landscapes. However, species that do not disperse through the urban matrix may eventually be lost from these fragments. Population extinctions may be precipitated by an increase in genetic differentiation among fragments and loss of genetic diversity within fragments, and these effects should become stronger with time. We analyzed population genetic structure in the dispersal limited Jerusalem cricket Stenopelmatus n. sp. ?santa monica?? in the Santa Monica Mountains and Simi Hills north of Los Angeles, California (CA), to determine the impacts of fragmentation over the past 70 years. MtDNA divergence was greater among urban fragments than within contiguous habitat and was positively correlated with fragment ...

2009-01-01

293

Imaging immune response in vivo

Genomics of human longevity

PurposeClinical trials have commenced to evaluate the feasibility of targeting malignant gliomas with genetically engineered cytolytic T-cells (CTLs) delivered directly...Full Text Available

2008-06-15

294

Genetic structure of gilthead seabream, Sparus aurata, in the Central Mediterranean Sea

In animal models, single-gene mutations in genes involved in insulin/IGF and target of rapamycin signalling pathways extend lifespan to a considerable extent. The genetic, genomic and epigenetic influences...Full Text Available

2011-01-12

295

British Library Electronic Table of Contents (United Kingdom)

The gilthead seabream, Sparus aurata, represents an important economic resource for Mediterranean aquaculture. In spite of its wide geographic distribution and economic importance, only recently studies have been carried out on the genetic composition of natural populations, which have revealed a picture of a heterogeneous degree of genetic differentiation among S. aurata populations. In this study an allozyme analysis of samples from six different collecting sites along the Italian and Croatian coasts was carried out, covering an area in the Central Mediterranean sea that has yet to be investigated through gene-enzyme systems. Data on 26 gene loci, 10 of which are polymorphic, indicate a slight but significant genetic structure (FST = 0.0167) of the species. A hierarchical analysis of pop...

2006-01-01

296

Genetic Architecture Underlying Variation in Extent and Remodeling of the Collateral Circulation

GENETIC STUDIES OF PIGMENTATION IN ...

RationaleCollaterals are arteriole-to-arteriole anastomoses that connect adjacent arterial trees. They lessen ischemic tissue injury by serving as endogenous bypass...Full Text Available

2010-08-20

297

Evidence for Epigenetic Interactions for Loci on Mouse Chromosome 1 Regulating Open Field Activity

... Strains Smith and -aybush were both grown in broth containing from 0.1 to 50 pg/ml of acriflavin, acridine orange, or proflavin. ...

1966-05-01

298

British Library Electronic Table of Contents (United Kingdom)

The expression of motor activity levels in response to novel situations is under complex genetic and environmental control. Several genetic loci have been implicated in the regulation of this behavioral phenotype, but their relationship to epigenetic and epistatic interactions is relatively unknown. Here, we report on a quantitative trait locus (QTL) on mouse chromosome 1 for novelty-induced motor activity in the open field, using chromosome substitution strains derived from a high active host strain (C57BL/6J) and a low active donor strain (A/J). The QTL for open field (horizontal distance moved) peaked at the location of Kcnj9, however, QTL detection was initially masked by an interplay of both grandparent genetic origin and genetic co-factors influencing behavior on chromosome 1. Our fi...

2009-01-01

299

Estimation of Genetic Parameters for Growth-Related Traits in 9-month Old of Two Korean Abalone Subspecies, Haliotis discus hannai and H. discus discus, by Using Multiple Traits of Animal Model

Embryonic Senescence and Laminopathies in a Progeroid Zebrafish Model

Full Text Available

2009-12-01

300

Distinct sensory representations of wind and near-field sound in the Drosophila brain

BackgroundMutations that disrupt the conversion of prelamin A to mature lamin A cause the rare genetic disorder Hutchinson-Gilford progeria syndrome and a group of laminopathies....Full Text Available

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301

Current Projects - Human Nutrition Research Center on Aging ...

Behavioral responses to wind are thought to play a critical role in controlling the dispersal and population genetics of wild Drosophila species1,Full Text Available

2009-03-12

302

diet and genetic obesity metabolic defects and inflammation. To determine the role of adipocyte death in promoting adipose tissue inflammation and insulin resistance in animal...

2011-08-31

303

Culture and cooperation

Consumer attitudes and decision-making with regard to genetically engineered food products: A review of the literature and a presentation of models for future research

Does the cultural background influence the success with which genetically unrelated individuals cooperate in social dilemma situations? In this paper, we provide an answer by analysing the data of Full Text Available

2010-09-12

304

Comparing Genomes within the Species Mycobacterium tuberculosis

Executive summary 1. Few studies have to date explained consumer attitudes and purchase decisions with regard to genetically engineered food products. However, the increased marketing of genetically engineered food products and the considerable concern that consumers seem to express with regard to the technology call for the development of a theoretical basis for research into these issues. 2. The aim of the paper is to present three models which we have developed to explain consumer attitudes, buying behaviour and attitude change with regard to genetically engineered food products. All three models build on established consumer behaviour theory and on existing and comparable research in the field. 3. Consumer attitudes toward genetic engineering in food products are explained in an attitude model that builds on Fishbein's multiattribute attitude model. The model deviates from Fishbein's model in a ...

1998-01-01

305

Combining Genetics and Population History in the Study of Ethnic Diversity in the People's Republic of China

The study of genetic variability within natural populations of pathogens may provide insight into their evolution and pathogenesis. We used a Mycobacterium tuberculosis high-density...Full Text Available

2001-04-01

306

Can microRNAs act as biomarkers of aging?

... some Central Asian populations (Zerjal et al. 2002). Haplogroup W has a similar Middle Eastern origin, and again ... ...

307

Allozyme Divergence in Two Syntopic Liolaemus of the Liolaemus monticola Group (Squamata: Tropiduridae)

Aging can be defined as a progressive decline in physiological efficiency regulated by an extremely complex multifactorial process. The genetic makeup of an individual appears to dictate this rate...Full Text Available

308

AEC syndrome - Genetics Home Reference

... shareware for population genetic analysis. Molecular Biology and Biotecnology Centre, Univ. of Alberta, Canada. enlarge figure Fig. ... ...

309

An evaluation of current methods of diagnosing colorectal cancer in the United Kingdom

What genes are related to AEC syndrome? AEC syndrome is caused by mutations in the TP63 gene. This gene provides instructions for making a protein known as p63, which plays an...

2011-10-15

310

Quantitative genetic activity graphical profiles for use in chemical evaluation

Colorectal cancer (CRC) is a highly conversed topic, particularly since implementation of screening for CRC is imminent within the U.K. Aims: The aim of this research project was to examine the diagnostic tools currently used within the UK to detect CRC and their impact on the aetiology and epidemiology of CRC. Methodology: The complexity of the research topic lent itself towards a literature review. A systematic approach of researching was therefore adopted to analyse and critically evaluate the reliability and validity of articles. Electronic databases including AMED, Cancerlit, CINHAL, the Cochrane Library, EMBASE, MEDLINE and EBM-Reviews were utilised to provide a wide spectrum of recent and relevant articles. Other research strategies involved looking for books relating to the topics, which were kept to within 6 years of publication to maintain accuracy of information. Selected websites, such as NICE, the Department of Health, NHS websites ...

2009-05-15

311

Optimal selection of capacitors for radial distribution systems using a genetic algorithm

A graphic approach, terms a Genetic Activity Profile (GAP), was developed to display a matrix of data on the genetic and related effects of selected chemical agents. The profiles provide a visual overview of the quantitative (doses) and qualitative (test results) data for each chemical. Either the lowest effective dose or highest ineffective dose is recorded for each agent and bioassay. Up to 200 different test systems are represented across the GAP. Bioassay systems are organized according to the phylogeny of the test organisms and the end points of genetic activity. The methodology for producing and evaluating genetic activity profile was developed in collaboration with the International Agency for Research on Cancer (IARC). Data on individual chemicals were compiles by IARC and by the US Environmental Protection Agency (EPA). Data are available on 343 compounds selected from volumes 1-53 of the IARC ...

1990-06-27

312

Nucleotide sequence and genetic analysis of a 13.1-kilobase-pair Pseudomonas denitrificans DNA fragment containing five cob genes and identification of structural genes encoding Cob(I)alamin adenosyltransferase, cobyric acid synthase, and bifunctional cobinamide kinase-cobinamide phosphate guanylyltransferase.

In this paper, a new design methodology for determining the size, location, type and number of capacitors to be placed on a radial distribution system is presented. The objective is to minimize the peak power losses and the energy losses in the distribution system considering the capacitor cost. A sensitivity analysis based method is used to select the candidate locations for the capacitors. A new optimization method using a Genetic Algorithm is proposed to determine the optimal selection of capacitors. Test results have been presented along with the discussion of the algorithm.

1994-08-01

313

Mobilization of the genetically engineered plasmid pHSV106 from Escherichia coli HB101(pHSV106) to Enterobacter cloacae in drinking water.

A 13.1-kb DNA fragment carrying Pseudomonas denitrificans cob genes has been sequenced. The nucleotide sequence and genetic analysis revealed that this fragment contained five different cob genes named...Full Text Available

1991-10-01

314

Liposome technology. Volume II: Incorporation of drugs, proteins and genetic material

We have used triparental matings to demonstrate transfer (mobilization) of the nonconjugative genetically engineered plasmid pHSV106, which contains the thymidine kinase gene of herpes simplex virus...Full Text Available

1991-01-01

315

Invasiveness and persistence of Salmonella enteritidis, Salmonella typhimurium, and a genetically defined S. enteritidis aroA strain in young chickens.

These three volumes cover liposome technology in pharmacology and medicine. Contributors emphasize methodology used in their own laboratories, and include a brief introduction, coverage of relevant literature, applications and critical evaluations for the methods they describe. Volume II presents procedures for the entrapment of a number of drugs, including genetic material, into selected types of liposomes.

1984-01-01

316

Genetics and biochemistry of Clostridium relevant to development of fermentation processes

Newly hatched chicks were dosed orally with a Salmonella typhimurium wild-type strain, an S. enteritidis wild-type strain, and a genetically defined S. enteritidis aroA vaccine candidate, strain CVL30....Full Text Available

1994-11-01

317

Genetic and somatic effects in animals maintained on tritiated water

It is the purpose of this review to draw together the recent research adding to our understanding of the molecular nature of Clostridia. The thrust here is to emphasize those research advances in biochemistry and genetics that bear upon future development of fermentation processes employing the Clostridia. 222 refs., 10 figs., 5 tabs.

1984-01-01

318

Generalized genetic code. A note on order-isomorphism/order-equivalence relations

The possible genetic (dominant lethal mutations (DLM) and cytogenetic changes in the regenerating liver) and somatic (hematopoietic stem cell changes, growth and nonspecific life time shortening) effects in mice maintained on tritiated water (HTO) over two generations was investigated. Results to date are summarized. (ACR)

1981-01-01

319

Estimation of organ dose during radiological and computer tomographic examinations with calculations of the somatically significant doses

Constructive and combinatorial relationships between order-isomorphisms and order-equivalence classes within the generalized genetic code are presented, not only for the biologically relevant groups of order 4, but also for finite groups of arbitrary order. The main result is the derivation of the number (and types) or order-equivalence classes for a group of order n. Finally, an extension of this work to all biologically admissible alternative codes is discussed.

1982-01-01

320

Estimation of organ dose during radiological and computer tomographic examinations with calculations of the somatically significant doses

The risks from radiation exposure during radiological diagnosis has usually been estimated in relation to genetic changes. Relevant information has been expressed as the genetically significant dose. In this paper we attempt to produce an analogous measure for evaluating the somatic risk in the form of a somatically significant dose index for radiological and CT examinations. It is shown that, for both types of examination, the two risk factors may be entirely different.

1980-10-01

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321

Biological effects and health risks following to the exposition to ionizing radiation

The risks from radiation exposure during radiological diagnosis has usually been estimated in relation to genetic changes. Relevant information has been expressed as the genetically significant dose. In this paper we attempt to produce an analogous measure for evaluating the somatic risk in the form of a somatically significant dose index for radiological and CT examinations. It is shown that, for both types of examination, the two risk factors may be entirely different. (orig.).

1980-01-01

322

A Genetic Screen for Ribosomal DNA Silencing Defects Identifies Multiple DNA Replication and Chromatin-Modulating Factors

Late somatic and genetic radiation effects are imperfectly understood, particularly in the human species. However the available information is sufficient to draw reasonably precise risk estimates in man for many types of damage by means of scientifically justifiable procedures and with the necessary caution. This overall absolute risk of major somatic and genetic damage may be set at around 10"-"4/rad of chronic whole-body doses.

1976-01-01

323

The impact of stellar model spectra in disc detection

Transcriptional silencing in Saccharomyces cerevisiae occurs at several genetic loci, including the ribosomal DNA (rDNA). Silencing at telomeres (telomere position effect [TPE])...Full Text Available

1999-04-01

324

British Library Electronic Table of Contents (United Kingdom)

Abstract We present a study of the impact of different model groups in the detection of circumstellar debris discs. Almost all previous studies in this field have used kurucz (atlas9) model spectra to predict the stellar contribution to the flux at the wavelength of observation, thus determining the existence of a disc excess. Only recently have other model groups or families like marcs and nextgen (phoenix) become available to the same extent as atlas9. This study aims to determine whether the predicted stellar flux of a disc target can change with the choice of model family can a disc excess be present in the use of one model family whilst being absent from another. A simple comparison of kurucz model spectra with marcs and nextgen model spectra of identical stellar parameters was conduc...

2010-01-01

325

The Role of Home Economics: Population and Family Life Education in Nigeria

Teaching and Learning Guide for: Fairness and Power in Family Organization

Home economics is a dynamic field that imparts knowledge intended to help people adapt to their environment by making effective use of human and material resources. Hence, the profession values global concerns for the environment, human rights, health, and well-being. In Nigeria, home economics teachers must also consider the role they play in programs such as family life education, poverty alleviation, and universal basic education. In particular, home economics is one of the subjects through which core messages of the country's Population and Family Life Education program are to be integrated at the secondary school level. In this article, the author discusses the outcomes of this program and provides recommendations for teachers teaching this subject. (Contains 1 table and 1 resource.)

2004-12-01

326

British Library Electronic Table of Contents (United Kingdom)

This guide accompanies the following article: Gabrielle Poeschl, `What Family Organization Tells Us about Fairness and Power in Marital Relationships', Social and Personality Compass 1/1 (2007): 557-571, 10.1111/j.1751-9004.2007.00026.x Author's Introduction One thing that often strikes me, when I talk with people, is the human capacity to accept and defend surprising aspects of the social life. Thus, we have some feeling that the separation between the domestic and the public spheres has not always existed, but we are ready to assume that in the first human groups, men went out hunting to feed their family, while women stayed in the camp to take care of the children. Even in the face of evidence to the contrary, we are reluctant to question the opinion that men and women differ in persona...

2009-01-01

327

String Universality in Six Dimensions

Generalized Linear Models in Family Studies

In six dimensions, cancellation of gauge, gravitational, and mixed anomalies strongly constrains the set of quantum field theories which can be coupled consistently to gravity. We show that for some classes of six-dimensional supersymmetric gauge theories coupled to gravity, the anomaly cancellation conditions are equivalent to tadpole cancellation and other constraints on the matter content of heterotic/type I compactifications on K3. In these cases, all consistent 6D supergravity theories have a realization in string theory. We find one example which may arise from a novel string compactification, and we identify a new infinite family of models satisfying anomaly factorization. We find, however, that this infinite family of models, as well as other infinite families of models previously identified by Schwarz are pathological. We suggest that it may be feasible to demonstrate that there is a string theoretic realization of ...

2009-01-01

328

Familial unilateral deafness and delayed endolymphatic hydrops

Generalized linear models (GLMs), as defined by J. A. Nelder and R. W. M. Wedderburn (1972), unify a class of regression models for categorical, discrete, and continuous response variables. As an extension of classical linear models, GLMs provide a common body of theory and methodology for some seemingly unrelated models and procedures, such as the logistic, Poisson, and probit models, that are increasingly used in family studies. This article provides an overview of the principle and the key components of GLMs, such as the exponential family of distributions, the linear predictor, and the link function. To illustrate the application of GLMs, this article uses Canadian national survey data to build an example focusing on the number of close friends among older adults. The article concludes with a discussion of the strengths and weaknesses of GLMs.

2005-11-01

329

British Library Electronic Table of Contents (United Kingdom)

Delayed endolymphatic hydrops (DEH) is a unique disorder characterized by fluctuating otologic symptoms in the setting of preexisting unilateral deafness. The symptoms include aural fullness, fluctuating hearing, and/or episodes of vertigo similar to those observed in Meniere disease and may occur ipsilateral or contralateral to the previously deafened ear. In most reported cases, the unilateral deafness has been a profound sensorineural hearing loss with a sudden onset that has been variously attributed to bacterial or viral labyrinthitis, acoustic or cranial trauma, otosclerosis, and congenital CMV infection. Familial occurrence of the syndrome has not previously been reported in the literature. In this report, we describe two possible familial instances of delayed DEH. These patients ra...

2007-01-01

330

Distinguishing two groups of flavin reductases by analyzing the protonation state of an active site carboxylic acid

British Library Electronic Table of Contents (United Kingdom)

Abstract Flavin-containing reductases are involved in a wide variety of physiological reactions such as photosynthesis, nitric oxide synthesis, and detoxification of foreign compounds, including therapeutic drugs. Ferredoxin-NADP(H)-reductase (FNR) is the prototypical enzyme of this family. The fold of this protein is highly conserved and occurs as one domain of several multidomain enzymes such as the members of the diflavin reductase family. The enzymes of this family have emerged as fusion of a FNR and a flavodoxin. Although the active sites of these enzymes are very similar, different enzymes function in opposite directions, that is, some reduce oxidized nicotinamide adenine dinucleotide phosphate (NADP+) and some oxidize reduced nicotinamide adenine dinucleotide phosphate (NADPH). In t...

2011-01-01

331

Cytoplasmic p63 immunohistochemistry is a useful marker for muscle differentiation: an immunohistochemical and immunoelectron microscopic study

British Library Electronic Table of Contents (United Kingdom)

TP63, a member of the TP53 gene family, is a nuclear marker of myoepithelial cells. Antibody against p63 is frequently used to aid in the diagnosis of prostate carcinoma, as well as in the identification of myoepithelial cells in other tissues including the breast. p63 is also a marker for squamous cell carcinoma. Recently, it was found that all p53 family members are involved in regulating the process of muscle differentiation through the retinoblastoma (RB) protein. Ablation of these p53 family functions blocks the differentiation program and promotes malignant transformation by enabling cooperating oncogenes to transform myoblasts. We therefore studied p63 expression in a number of neoplasms with myogenic differentiation. Immunohistochemical staining for p63 was performed on paraffin se...

2011-01-01

332

Construction cost impact analysis of the U.S. Department of Energy mandatory performance standards for new federal commercial and multi-family, high-rise residential buildings

Comparative biochemistry of betaine biosynthesis and accumulation in diverse dicot families

In accordance with federal legislation, the U.S. Department of Energy (DOE) has conducted a project to demonstrate use of its Energy Conservation Voluntary Performance Standards for Commercial and Multi-Family High-Rise Residential Buildings; Mandatory for New Federal Buildings; Interim Rule (referred to in this report as DOE-1993). A key requisite of the legislation requires DOE to develop commercial building energy standards that are cost effective. During the demonstration project, DOE specifically addressed this issue by assessing the impacts of the standards on (1) construction costs, (2) builders (and especially small builders) of multi-family, high-rise buildings, and (3) the ability of low-to moderate-income persons to purchase or rent units in such buildings. This document reports on this project.

1993-12-01

333

A partnership approach to service needs assessment with family caregivers of an aging relative living at home: A qualitative analysis of the experiences of caregivers and practitioners

Salt stress elicits betaine accumulation to high levels in species from several diverse dicot families (Chenopodiaceae, Amaranthaceae, Convolvulaceae, Solanaceae, and Asteraceae). FAM-MS studies with deuterated precursors showed that species from all these families synthesize betaine from choline. Enzyme assays and immunotitration data showed that all accumulating species contained betaine aldehyde dehydrogenase (BADH) enzyme activity recognized by antibodies raised against purified BADH isolated from Spinacia oleracea. Immunoblotting indicated that the BADH monomer was in all cases of Mr {approx} 63,000. The similarity of BADH in the different species is consistent with a single evolutionary origin for the betaine pathway. This was supported by the presence in immunoblots of a cross-reacting band at Mr {approx} 63,000 in Magnolia x Soulangiana, a primitive angiosperm.

1989-04-01

334

British Library Electronic Table of Contents (United Kingdom)

Background: As the global population ages, support for family caregivers who provide the bulk of care to community-dwelling older people is becoming ever more important. However, in many countries, homecare-service practitioners currently do not follow a systematic approach to assessing and responding to caregiver needs. Objectives: The aim of this study was to explore the experiences of caregivers and practitioners who took part in a field test of the Family Caregivers Support Agreement (FCSA) tool, a modified version of the Carers Outcome Agreement Tool (COAT) initially developed as the result of an Anglo-Swedish study. Both the COAT and the FCSA are designed to facilitate partnerships between caregivers and practitioners so that needs assessment and subsequent support services are negot...

2010-01-01

335

Genetic studies of fertility and pathogenicity in Magnaporthe grisea (Pyricularia oryzae)

Genetic diversity associated with in vitro and conventional bud propagation of Saccharum varieties using RAPD analysis

Crosses between field isolates of Magnaporthe grisea (anamorph, Pyricularia oryzae Cav. and Pyricularia grisea) have led to the development of fertile laboratory strains that infect goosegrass and/or weeping lovegrass. These strains may now be utilized in a rigorous genetic analysis of host species specificity and general pathogenicity. Attempts to improve the fertility of rice pathogens for the goal of undertaking a genetic analysis of host cultivar specificity have so far been unsuccessful. Crosses between M. grisea strains that infect rice, goosegrass or weeping lovegrass demonstrate that host species specificity differences between field isolates of this fungus in some cases have a complete genetic basis, and in other cases have a simple genetic basis. Crosses between a field isolate of the pathogen that infects weeping lovegrass and a field isolate that infects goosegrass have resulted in the ...

1984-01-01

336

British Library Electronic Table of Contents (United Kingdom)

Abstract Polymorphisms in the genomic DNA of eight varieties maintained by conventional bud propagation (via rhizomes) and by in vitro shoot tip cultures were detected by RAPD analysis of sugarcane varieties. The study estimated the genetic diversity induced after in vitro multiplication of these varieties. Higher (28.9%) and lower (12%) numbers of polymorphic bands were detected in plants propagated via rhizomes; the genetic similarity estimate varying from 0.63 to 0.80. Plants of SP90-3723 and SP91-1049, or RB85-5113 and SP90-3723, varieties involving greater genetic distances may be indicated as progenitors in breeding programmes. In vitro multiplication of RB86-7515, RB85-5113, RB83-5054 and SP86-42 varieties increases genetic variability, while in vitro multiplication of SP91-1049, SP...

2008-01-01

337

PCDD/F and "Dioxin-like" PCB emissions from iron ore sintering plants in the UK

British Library Electronic Table of Contents (United Kingdom)

Investigations have been carried out at the three Corus UK sinter plants over the period 2002-2004 to characterise the emissions of both 2,3,7,8-PCDD/Fs and WHO-12 PCBs, to estimate annual mass releases of these organic micro-pollutants using the I-TEF and WHO-TEF schemes, and to investigate the formation of PCBs in the iron ore sintering process. Results showed that the sintering of iron ore produces a characteristic WHO-12 PCB and PCDD/F congener pattern that is substantially the same for all UK sinter plants. With regard to WHO-12 PCBs, the most abundant congeners were typically PCBs 118 (6-9ngNm-3), 105 (2-4ngNm-3) and 77 (2-3ngNm-3). All other WHO-12 PCBs were also detected at concentrations around 1ngNm-3. All sinter plants investigated exhibited very similar TEQ concentrations. WHO-...

2006-01-01

338

Biological responses to the chemical recovery of acidified fresh waters in the UK

A scoping study: demand side measures on the UK electrical system

We report biological changes at several UK Acid Waters Monitoring Network lakes and streams that are spatially consistent with the recovery of water chemistry induced by reductions in acid deposition. These include trends toward more acid-sensitive epilithic diatom and macroinvertebrate assemblages, an increasing proportional abundance of macroinvertebrate predators, an increasing occurrence of acid-sensitive aquatic macrophyte species, and the recent appearance of juvenile (<1 year old) brown trout in some of the more acidic flowing waters. Changes are often shown to be directly linked to annual variations in acidity. Although indicative of biological improvement in response to improving water chemistry, 'recovery' in most cases is modest and very gradual. While specific ecological recovery endpoints are uncertain, it is likely that physical and biotic interactions are influencing the rate of recovery of certain groups of organisms at particular sites. - ...

2005-09-01

339

flhDC, the Flagellar Master Operon of Xenorhabdus nematophilus: Requirement for Motility, Lipolysis, Extracellular Hemolysis, and Full Virulence in Insects

The study is intended to eventually bring about a number of improvements in the UK electrical system, particularly in regard to Demand Side Management (DSM). Among the benefits envisaged are (a) increased security of supply when the network is under stress; (b) reduction in costs; (c) simpler outage management; (d) carbon saving and (e) increased energy efficiency. So far, these potential benefits have attracted little attention in the residential and small business sectors of the market: suggested reasons for this are listed. Taking into account the experience of other countries, three options are presented for a UK DSM programme: they are (i) customer initiated; (ii) supplier initiated and (iii) distributor initiated. At present, all the suggested options need further study and to aid the development for small customers, five possible initiatives are suggested. This final report (95 pages) includes a detailed description of the research ...

2005-07-01

340

Women's autonomy in household decision-making: a demographic study in Nepal

Xenorhabdus is a major insect pathogen symbiotically associated with nematodes of the family Steinernematidae. This motile bacterium displays swarming behavior on suitable media, but...Full Text Available

2000-01-01

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341

Wnt3a Induces Myofibroblast Differentiation by Upregulating TGF-? Signaling Through SMAD2 in a ?-Catenin-Dependent Manner

BackgroundHow socio-demographic factors influence women's autonomy in decision making on health care including purchasing goods and visiting family and relatives are very poorly...Full Text Available

342

Which Circulating Antioxidant Vitamins Are Confounded by Socioeconomic Deprivation? The MIDSPAN Family Study

Growing evidence suggests the Wnt family of secreted glycoproteins and their associated signaling pathways, linked to development, are recapitulated during wound repair and regeneration events. However,...Full Text Available

343

Urinary tract infection in children.

BackgroundAntioxidant vitamins are often described as having “independent” associations with risk of cancer, cardiovascular disease (CVD) and mortality. We aimed...Full Text Available

344

Ultrabiomicroscopic-Histopathologic Correlations in Individuals with Autosomal Dominant Congenital Microcoria: Three-Generation Family Report

During 1968-77, 572 consecutive children with one or more positive urine cultures who were referred by their family doctors to one paediatric surgical outpatient clinic were investigated and prospectively...Full Text Available

1984-08-04

345

The role of the antioxidant and longevity-promoting Nrf2 pathway in metabolic regulation

BackgroundCongenital microcoria (CMC) is due to a maldevelopment of the dilator pupillae muscle of the iris, with a pupil diameter of less than 2 mm. It is associated with juvenile...Full Text Available

346

The opiorphin gene (ProL1) and its homologues function in erectile physiology

Purpose of ReviewThe vertebrate cap’n’collar family transcription factor Nrf2 and its invertebrate homologs SKN-1 (in worms) and CncC (in flies) function...Full Text Available

2011-01-01

347

The Potential for pathogenicity was present in the ancestor of the Ascomycete subphylum Pezizomycotina

OBJECTIVETo determine if ProL1, a member of the opiorphin family of genes, can modulate erectile physiology, as it encodes a peptide which acts as...Full Text Available

2008-09-01

348

The Exceptionally Large Genome of Hendra Virus: Support for Creation of a New Genus within the Family Paramyxoviridae

BackgroundPrevious studies in Ascomycetes have shown that the function of gene families of which the size is considerably larger in extant pathogens than in non-pathogens could be...Full Text Available

349

The Anopheles gambiae glutathione transferase supergene family: annotation, phylogeny and expression profiles

An outbreak of acute respiratory disease in Hendra, a suburb of Brisbane, Australia, in September 1994 resulted in the deaths of 14 racing horses and a horse trainer. The causative agent was a new member...Full Text Available

2000-11-01

350

Temporal trends in hepatitis B and C infection in family blood donors from interior Sindh, Pakistan

BackgroundTwenty-eight genes putatively encoding cytosolic glutathione transferases have been identified in the Anopheles gambiae genome. We manually annotated these...Full Text Available

351

Temporal and Tissue-Specific Patterns of Pon3 Expression in Mouse: In situ Hybridization Analysis

BackgroundHepatitis B (HBV) and C (HCV) infections are a serious global and national public health problem. Earlier studies have reported increasing rates of hepatitis infection...Full Text Available

352

Temperature-induced opening of TRPV1 ion channel is stabilized by the pore domain

PON3 is a member of the paraoxonase gene family that includes PON1 and PON2. For example, PON3 and PON1 share...Full Text Available

2010-01-01

353

Synergistic Operation of the CAR2 (Ornithine Transaminase) Promoter Elements in Saccharomyces cerevisiae

SummaryTRPV1 is the founding and best-studied member of the family of temperature-activated transient receptor potential ion channels (thermoTRPs). Voltage, chemicals, and heat...Full Text Available

2010-06-01

354

Sugarcane pests and their management

Dal82p binds to the UIS_ALL sites of allophanate-induced genes of the allantoin-degradative pathway and functions synergistically with the GATA family Gln3p and Gat1p transcriptional...Full Text Available

1999-11-01

355

Structural Characterization and Expression Analysis of the SERK/SERL Gene Family in Rice (Oryza sativa)

This book chapter discusses sugarcane culture and history, describes arthropod biologies and injury, and identifies sugarcane pest management factors to consider for people interested in commercial sugarcane production. Arthropod groups include 10 orders and 40 families. Sugarcane pest management ...

356

Structural Basis for Acetylated Histone H4 Recognition by the Human BRD2 Bromodomain*

Somatic embryogenesis (SE) is the developmental restructuring of somatic cells towards the embryogenic pathway and forms the basis of cellular totipotency in angiosperms. With the availability of full-length...Full Text Available

2009-01-01

357

Sequence and expression of the zebrafish alpha-actinin gene family reveals conservation and diversification among vertebrates

Recognition of acetylated chromatin by the bromodomains and extra-terminal domain (BET) family proteins is a hallmark for transcriptional activation and anchoring viral genomes to mitotic chromosomes...Full Text Available

2010-03-05

358

Safety Nets and Scaffolds: Parental Support in the Transition to Adulthood

alpha-actinins are actin microfilament crosslinking proteins. Vertebrate actinins fall into two classes: the broadly-expressed actinins 1 and 4 (actn1 and actn4)...Full Text Available

2009-11-01

359

Role of serum carrier proteins in the peripheral metabolism and tissue distribution of thyroid hormones in familial dysalbuminemic hyperthyroxinemia and congenital elevation of thyroxine-binding globulin.

Using longitudinal data from the Youth Development Study (analytic sample N = 712), we investigate how age, adult role acquisition and attainments, family resources, parent-child relationship...Full Text Available

2011-04-01

360

Reversal of Depressed Behaviors by p11 Gene Therapy in the Nucleus Accumbens

To investigate the role of thyroxine-binding globulin (TBG) and albumin in the availability of thyroid hormones to peripheral tissues, comprehensive kinetic studies of thyroxine (T4) and triiodothyronine...Full Text Available

1987-08-01

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

361

Retinoic acid X receptor in the diploblast, Tripedalia cystophora

The etiology of major depression remains unknown, but dysfunction of serotonergic signaling has long been implicated in the pathophysiology of this disorder. p11 is an S100 family member recently...Full Text Available

2010-10-20

362

Psychosocial Characteristics of Optimum Performance in Isolated ...

Nuclear hormone receptors comprise a characteristic family of transcription factors found in vertebrates, insects and nematodes. Here we show by cDNA and gene cloning that a Cnidarian, Tripedalia...Full Text Available

1998-11-10

363

Prenatal diagnosis for recessive dystrophic epidermolysis bullosa in 10 families by mutation and haplotype analysis in the type VII collagen gene (COL7A1).

Studies were assigned values based on whether they were anecdotal or ... or family income), work experience, birth order, military or civilian ...... observed with submarine personnel and polar expeditioners (Sandal et al., 1996). ...

364

Physiologic aspects of continence after colectomy, mucosal proctectomy, and endorectal ileo-anal anastomosis.

BACKGROUND: Epidermolysis bullosa (EB) is a group of heritable diseases that manifest as blistering and erosions of the skin and mucous membranes. In the dystrophic forms of EB (DEB), the diagnostic...Full Text Available

1996-01-01

365

Paediatric Palliative Care: Theory to Practice

We examined the physiology of continence in 12 patients at least four months after colectomy, mucosal proctectomy, and endorectal ileo-anal anastomosis for ulcerative colitis and familial polyposis....Full Text Available

1982-04-01

366

Overweight and obesity among school-going children of Lucknow city

Paediatric palliative care is a holistic approach aimed at addressing the complex issues related to the care of children and families facing chronic life limiting illnesses. The needs of children are...Full Text Available

2011-01-01

367

Orp1, a member of the Cdc18/Cdc6 family of S-phase regulators, is homologous to a component of the origin recognition complex.

Background:Childhood obesity is increasingly being observed with changing lifestyles of families. The magnitude of overweight ranges from 9% to 27.5% and obesity ranges...Full Text Available

2011-05-01

368

On the Austral-Antarctic stenothoids Proboloides, Metopoides, Torometopa and Scaphodactylus (Crustacea Amphipoda) Part 2: the genus Proboloides, with description of two new genera and the transfer of two nominal species to Metopoides

cdc18+ of Schizosaccharomyces pombe is a periodically expressed gene that is required for entry into S phase and for the coordination of S phase with mitosis. cdc18+ is related to the Saccharomyces...Full Text Available

1995-12-19

369

Novel Analogs and Stereoisomers of the Marine Toxin Neodysiherbaine with Specificity for Kainate Receptors

AbstractThis is the second part of a revision of the most plesiomorphic genera in the amphipod family Stenothoidae sensu lato...Full Text Available

370

Modulation of Expression of the ToxR Regulon in Vibrio cholerae by a Member of the Two-Component Family of Response Regulators

Antagonists for kainate receptors (KARs), a family of glutamate-gated ion channels, are efficacious in a number of animal models of neuropathologies, including epilepsy, migraine pain, and anxiety....Full Text Available

2008-02-01

371

The ToxRS system in Vibrio cholerae plays a central role in the modulation of virulence gene expression in response to environmental stimuli. An integration of multiple signalling inputs...Full Text Available

1998-12-01

372

Meson spectrum

Mammalian Sirt1: insights on its biological functions

Using the Klein-Gordon equation with a box potential, a mass formula describing the family of nonflavored meson states with I = 1 is derived. The energy levels calculated agree with those observed within an accuracy of approx. 5%. In the model discussed quarks behave like tachyons.

1987-12-01

373

Low level of polymorphism in two putative NPR1 homologs in the Vitaceae family

Sirt1 (member of the sirtuin family) is a nicotinamide adenosine dinucleotide (NAD)-dependent deacetylase that removes acetyl groups from various proteins. Sirt1 performs a wide variety of functions...Full Text Available

374

Localization of Reversion-Induced LIM Protein (RIL) in the Rat Central Nervous System

BackgroundGrapevine is subjected to numerous pests and diseases resulting in the use of phytochemicals in large quantities. The will to decrease the use of phytochemicals leads to...Full Text Available

375

Lizards in the ecology of salmonellosis in Panama.

Reversion-induced LIM protein (RIL) is a member of the ALP (actinin-associated LIM protein) subfamily of the PDZ/LIM protein family. RIL serves as an adaptor protein and seems to regulate cytoskeletons....Full Text Available

2009-02-28

376

Ixodes scapularis tick serine proteinase inhibitor (serpin) gene family; annotation and transcriptional analysis

Enteropathogenic bacteria was isolated from 131 of 447 (29.4%) neotropical Panamanian lizards belonging to 34 species of seven families. Overall, 147 strains of bacteria were isolated comprising 26...Full Text Available

1981-05-01

377

Involvement of the chemokine-like receptor GPR33 in innate immunity?

BackgroundSerine proteinase inhibitors (Serpins) are a large superfamily of structurally related, but functionally diverse proteins that control essential proteolytic pathways in...Full Text Available

378

Insect juvenile hormone resistance gene homology with the bHLH-PAS family of transcriptional regulators

Chemokine receptors control leukocyte chemotaxis and cell-cell communication but have also been associated with pathogen entry. GPR33, an orphan member of the chemokine-like receptor family,...Full Text Available

2010-05-28

379

Infinite bubbling in non-K\\"ahlerian geometry

Juvenile hormone analog (JHA) insecticides are relatively nontoxic to vertebrates and offer effective control of certain insect pests. Recent reports of resistance in whiteflies and mosquitoes demonstrate...Full Text Available

1998-03-17

380

If I Had - A Family History of Heart Disease

In a holomorphic family $(X_b)_{b\\in B}$ of non-K\\"ahlerian compact manifolds, the holomorphic curves representing a fixed 2-homology class do not form a proper family in general. The deep source of this fundamental difficulty in non-K\\"ahler geometry is the {\\it explosion of the area} phenomenon: the area of a curve $C_b\\subset X_b$ in a fixed 2-homology class can diverge as $b\\to b_0$. This phenomenon occurs frequently in the deformation theory of class VII surfaces. For instance it is well known that any minimal GSS surface $X_0$ is a degeneration of a 1-parameter family of simply blown up primary Hopf surfaces $(X_z)_{z\\in D\\setminus\\{0\\}}$, so one obtains non-proper families of exceptional divisors $E_z\\subset X_z$ whose area diverge as $z\\to 0$. Our main goal is to study in detail this non-properness phenomenon in the case of class VII surfaces. We will prove that, under certain ...

2010-01-01

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381

Identification of Host Proteins Associated with Retroviral Vector Particles by Proteomic Analysis of Highly Purified Vector Preparations?

... Hospital & University Hospital Basel) If I Had - Pre-diabetes - Dr. Venkat Narayan, MD, MSc, MBA, Rollins School ... School, Massachusetts General Hospital, Discusses the Treatment of Diabetes Back to Home Page If I Had - A ...

382

Hysteretic Behavior of Proprotein Convertase 1/3 (PC1/3)

The Moloney murine leukemia virus (MMLV) belongs to the Retroviridae family of enveloped viruses, which is known to acquire minute amounts of host cellular proteins both on the surface...Full Text Available

2008-02-01

383

Hsp12.6 Expression Is Inducible by Host Immunity in Adult Worms of the Parasitic Nematode Nippostrongylus brasiliensis

The proprotein convertases (PCs) are calcium-dependent proteases responsible for processing precursor proteins into their active forms in eukariotes. The PC1/3 is a pivotal enzyme of this family that...Full Text Available

384

Generation of microsatellite repeat families by RTE retrotransposons in lepidopteran genomes

Heat shock proteins (Hsp) are a family of stress-inducible molecular chaperones that play multiple roles in a wide variety of animals. However, the roles of Hsps in parasitic nematodes remain largely...Full Text Available

385

Generation of a BAC-based physical map of the melon genome

BackgroundDeveloping lepidopteran microsatellite DNA markers can be problematical, as markers often exhibit multiple banding patterns and high frequencies of non-amplifying "null"...Full Text Available

386

Functional and Structural Analysis of a Key Region of the Cell Wall Inhibitor Moenomycin

BackgroundCucumis melo (melon) belongs to the Cucurbitaceae family, whose economic importance among horticulture crops is second only to Solanaceae. Melon has high...Full Text Available

387

Functional Interactions between Retinoblastoma and c-MYC in a Mouse Model of Hepatocellular Carcinoma

Moenomycin A (MmA) belongs to a family of natural products that inhibit peptidoglycan biosynthesis by binding to the peptidoglycan glycosyltransferases (PGTs), the enzymes that make the glycan...Full Text Available

2010-07-16

388

Family Gauge Symmetry as an Origin of Koide's Mass Formula and Charged Lepton Spectrum

Inactivation of the RB tumor suppressor and activation of the MYC family of oncogenes are frequent events in a large spectrum of human cancers. Loss of RB function and MYC activation are thought to...Full Text Available

389

Familial premature ovarian failure.

Koide's mass formula is an empirical relation among the charged lepton masses which holds with a striking precision. We present a model of charged lepton sector based on U(3)\\times SU(2) family gauge symmetry, which predicts Koide's formula within the present experimental accuracy. Radiative corrections as well as other corrections to Koide's mass formula are kept under control. We adopt a known mechanism, through which the charged lepton spectrum is determined by the vacuum expectation value of a 9-component scalar field \\Phi. On the basis of this mechanism, we implement the following mechanisms into our model: (1) The radiative correction induced by family gauge interaction cancels the QED radiative correction to Koide's mass formula, assuming a scenario in which the U(3) family gauge symmetry and SU(2)_L weak gauge symmetry are unified at 10^2-10^3 TeV scale; (2) A simple potential of \\Phi invariant under U(3)\\times ...

2009-01-01

390

Expression profiles of precursor and mature microRNAs under dehydration and high salinity shock in Populus euphratica

Premature menopause, ovarian failure younger than 40 years of age, is relatively rare but may preclude childbearing for some women who delay attempts at fertility. We present five kindreds in which...Full Text Available

1984-11-01

391

British Library Electronic Table of Contents (United Kingdom)

MicroRNAs (miRNAs) are small non-coding RNAs that play vital roles in plant abiotic stress responses via cleavage or translational inhibition of their target mRNAs. Populus euphratica is a typical stress-resistant sessile organism that grows in desert areas. Here, we identified sequences of 12 miRNA precursors from 11 families and 13 mature miRNAs from 12 families by PCR amplification in P. euphratica. To detect expression differences in mature miRNAs and their precursors under dehydration and high salinity shock in P. euphratica, we examined 14 miRNA precursors from 13 miRNA families and 17 mature miRNAs from 17 miRNA families using the SYBR Green RT?PCR assay. This is the first report of expression profiles for both precursor and mature miRNAs in P. euphratica. By profiling both the matu...

2011-01-01

392

Expression of leukotriene receptors in the rat dorsal root ganglion and the effects on pain behaviors

Expression of CD1d in human scalp skin and hair follicles: hair cycle related alterations

BackgroundLeukotrienes (LTs) belong to the large family of lipid mediators implicated in various inflammatory conditions such as asthma and rheumatoid arthritis. Four distinct types...Full Text Available

393

Expression and Characterization of the Mycobacterium tuberculosis Serine/Threonine Protein Kinase PknB

Background: CD1d belongs to a family of antigen presenting molecules that are structurally and distantly related to the classic major histocompatibility complex class I (MHC I)...Full Text Available

2005-12-01

394

Evolution of the nuclear ribosomal DNA intergenic spacer in four species of the Daphnia pulex complex

PknB is a member of the newly discovered eukaryotic-like protein serine/threonine kinase (PSTK) family of proteins. The pknB gene was cloned and expressed in Escherichia coli....Full Text Available

1999-11-01

395

Evidence of linkage disequilibrium in the Spanish polycystic kidney disease I population.

BackgroundConcerted evolution refers to the pattern in which copies of multigene families show high intraspecific sequence homogeneity but high interspecific sequence diversity....Full Text Available

396

Evidence for proteolytic cleavage of brevican by the ADAMTSs in the dentate gyrus after excitotoxic lesion of the mouse entorhinal cortex

Forty-one Spanish families with polycystic kidney disease 1 (PKD1) were studied for evidence of linkage disequilibrium between the disease locus and six closely linked markers. Four of these loci--three...Full Text Available

1994-05-01

397

Endocrine tumours in neurofibromatosis type 1, tuberous sclerosis and related syndromes

BackgroundBrevican is a member of the lectican family of aggregating extracellular matrix (ECM) proteoglycans that bear chondroitin sulfate (CS) chains. It is highly expressed in...Full Text Available

398

Empirically Defined Subtypes of Alcohol Dependence in an Irish Family Sample

Neurofibromatosis type 1 (NF-1) and tuberous sclerosis complex (TSC) are two familial syndromes known as phakomatoses that may be associated with endocrine tumors. These hereditary cutaneous...Full Text Available

2010-06-01

399

Emergence of Switch-Like Behavior in a Large Family of Simple Biochemical Networks

Alcohol dependence (AD) is clinically and etiologically heterogeneous. The goal of this study was to explore AD subtypes among a sample of 1, 221 participants in the Irish Affected Sib Pair...Full Text Available

2010-03-01

400

Effects of hyperbilirubinaemia on glutathione S-transferase isoenzymes in cerebellar cortex of the Gunn rat.

Bistability plays a central role in the gene regulatory networks (GRNs) controlling many essential biological functions, including cellular differentiation and cell cycle control. However, establishing...Full Text Available

2011-05-01

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401

Effects of PKA phosphorylation on the conformation of the Na,K-ATPase regulatory protein FXYD1

The glutathione S-transferases (GSTs) are a family of isoenzymes involved in the detoxication of a variety of electrophilic xenobiotics. The present investigation demonstrates that GST activity and...Full Text Available

1993-04-15

402

Effects of Cynodon dactylon on Stress-Induced Infertility in Male Rats

FXYD1 (phospholemman) is a member of an evolutionarily conserved family of membrane proteins that regulate the function of the Na,K-ATPase enzyme complex in specific tissues and specific physiological...Full Text Available

2009-11-01

403

Ectopic Expression of Constitutively Activated RACB in Barley Enhances Susceptibility to Powdery Mildew and Abiotic Stress1

Cynodon dactylon (Family: Poaceae) is known to be a tackler in Indian mythology and is offered to Lord Ganesha. It is found everywhere, even on waste land, road side, dry places, and...Full Text Available

2011-01-01

404

Drosophila melanogaster Methoprene-tolerant (Met) gene homologs from three mosquito species: members of PAS transcriptional factor family

Small RAC/ROP-family G proteins regulate development and stress responses in plants. Transient overexpression and RNA interference experiments suggested that the barley (Hordeum vulgare)...Full Text Available

2005-09-01

405

Development of small-molecule inhibitors of the group I p21-activated kinases, emerging therapeutic targets in cancer

The Methoprene-tolerant (Met) gene in Drosophila melanogaster has been shown to function in juvenile hormone (JH) action. Met...Full Text Available

2007-03-01

406

Crassulacean Acid Metabolism and Epiphytism Linked to Adaptive Radiations in the Orchidaceae1[OA

The p21-activated kinases (PAKs), immediate downstream effectors of the small G-proteins of the Rac/cdc42 family, are critical mediators of signaling pathways regulating cellular behaviors and...Full Text Available

2010-09-01

407

Correlation of Pain Scores, Analgesic Use, and Beck Anxiety Inventory Scores During Hospitalization in Lower Extremity Amputees

Species of the large family Orchidaceae display a spectacular array of adaptations and rapid speciations that are linked to several innovative features, including specialized pollination syndromes,...Full Text Available

2009-04-01

408

Common Familial Colorectal Cancer Linked to Chromosome 7q31: a genome-wide analysis

Post amputation pain can be debilitating for patients and families. Chronic pain is a common phenomenon after lower extremity amputation, occurring in up to 80% of this population. The purpose of this...Full Text Available

409

Collective trauma in northern Sri Lanka: a qualitative psychosocial-ecological study

Present investigations suggest that approximately 30% of colorectal cancer (CRC) cases arise on the basis of inherited factors. We hypothesize that the majority of inherited factors are moderately...Full Text Available

2008-11-01

410

Cloning of the mouse hepatitis virus (MHV) receptor: expression in human and hamster cell lines confers susceptibility to MHV.

BackgroundComplex situations that follow war and natural disasters have a psychosocial impact on not only the individual but also on the family, community and society. Just as the...Full Text Available

411

Chiropteran types I and II interferon genes inferred from genome sequencing traces by a statistical gene-family assembler

The cellular receptor for murine coronavirus mouse hepatitis virus (MHV)-A59 is a member of the carcinoembryonic antigen (CEA) family of glycoproteins in the immunoglobulin superfamily. We isolated...Full Text Available

1991-12-01

412

Characterization, phylogeny, alternative splicing and expression of Sox30 gene

BackgroundThe rate of emergence of human pathogens is steadily increasing; most of these novel agents originate in wildlife. Bats, remarkably, are the natural reservoirs of many...Full Text Available

413

Characterization of the functional gene and several processed pseudogenes in the human triosephosphate isomerase gene family.

BackgroundMembers of the Sox gene family isolated from both vertebrates and invertebrates have been proved to participate in a wide variety of developmental processes, including...Full Text Available

414

Chapter 2, A Quick-look at your Pay - NASAPeople

The functional gene and three intronless pseudogenes for human triosephosphate isomerase were isolated from a recombinant DNA library and characterized in detail. The functional gene spans 3.5 kilobase...Full Text Available

1985-07-01

415

Cardiac Myosin Is a Substrate for Zipper-interacting Protein Kinase (ZIPK)*

You receive an annuity if eligible -- requires 18 months service for FERS; and 60 ... You may use up to 104 hours of your accrued sick leave to care for sick family ...

416

Cadherin Mechanics and Complexation: The Importance of Calcium Binding

Zipper-interacting protein kinase (ZIPK) is a member of the death-associated protein kinase family associated with apoptosis in nonmuscle cells where it phosphorylates myosin regulatory light chain...Full Text Available

2010-02-19

417

Biotransformation of Explosives by the Old Yellow Enzyme Family of Flavoproteins

E-cadherins belong to a family of membrane-bound, cellular adhesion proteins. Their adhesive properties mainly involve the two N-terminal extracellular domains (EC1 and EC2). The junctions between these...Full Text Available

2005-12-01

418

Biogeography of Tick-Borne Bhanja Virus (Bunyaviridae) in Europe

Several independent studies of bacterial degradation of nitrate ester explosives have demonstrated the involvement of flavin-dependent oxidoreductases related to the old yellow enzyme (OYE) of yeast....Full Text Available

2004-06-01

419

Bacterial glycolipids and analogs as antigens for CD1d-restricted NKT cells

Bhanja virus (BHAV) is pathogenic for young domestic ruminants and also for humans, causing fever and affections of the central nervous system. This generally neglected arbovirus of the family Bunyaviridae...Full Text Available

2009-01-01

420

Avian Nephritis Virus (ANV) as a New Member of the Family Astroviridae and Construction of Infectious ANV cDNA

The CD1 family of proteins binds self and foreign glycolipids for presentation to CD1-restricted T cells. To identify previously uncharacterized active CD1 ligands, especially those of microbial origin,...Full Text Available

2005-02-01

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421

Autoantibodies to BRAF, a new family of autoantibodies associated with rheumatoid arthritis

The complete RNA genome of the avian nephritis virus (ANV) associated with acute nephritis in chickens has been molecularly cloned and sequenced. Excluding the poly(A) tail, the genome comprises 6,927...Full Text Available

2000-09-01

422

Apolipoprotein E-Mimetics Inhibit Neurodegeneration and Restore Cognitive Functions in a Transgenic Drosophila Model of Alzheimer's Disease

IntroductionBRAF (v raf murine sarcoma viral oncogene homologue B1) is a serine-threonine kinase involved in the mitogen-activated protein kinase (MAPK) signalling pathway, known...Full Text Available

2010-01-01

423

Ammonium and Nitrate Uptake by the Floating Plant Landoltia punctata

BackgroundMutations of the amyloid precursor protein gene (APP) are found in familial forms of Alzheimer's disease (AD) and some lead to the elevated production...Full Text Available

424

A wide spectrum of clinical and brain MRI findings in patients with SLC19A3 mutations

Background and AimsPlants from the family Lemnaceae are widely used in ecological engineering projects to purify wastewater and eutrophic water bodies. However, the biology of nutrient...Full Text Available

2007-02-01

425

A new perspective on phylogeny and evolution of tetraodontiform fishes (Pisces: Acanthopterygii) based on whole mitochondrial genome sequences: Basal ecological diversification?

BackgroundSLC19A3 (solute carrier family 19, member 3) is a thiamin transporter with 12 transmembrane domains. Homozygous or compound heterozygous mutations in SLC19A3 cause...Full Text Available

426

A neurodegenerative disease mutation that accelerates the clearance of apoptotic cells

BackgroundThe order Tetraodontiformes consists of approximately 429 species of fishes in nine families. Members of the order exhibit striking morphological diversity and radiated...Full Text Available

427

A modular approach to DC to DC power converters

Frontotemporal lobar degeneration is a progressive neurodegenerative syndrome that is the second most common cause of early-onset dementia. Mutations in the progranulin gene are a major cause of familial...Full Text Available

2011-03-15

428

A Patient Survey Assessing the Awareness and Acceptability of the Emergency Care Summary and Its Consent Model in Scotland

A familiar power inverter circuit, combined with a ferroresonant transformer and a simple control circuit, provides the basis for an economically attractive modular family of DC to DC converters. The circuit is readily adaptable to a wide range of input voltages and single or multiple output voltages.

1974-01-01

429

UK Achievements in the application of power fluidic technology for nuclear processing plants

BackgroundThe Emergency Care Summary (ECS) was introduced in 2006 to allow aspects of the general practitioner (GP; family doctor, equivalent to primary care physician) medical record...Full Text Available

430

TRADE AND ECONOMIC GEOGRAPHY: THE IMPACT OF EEC ACCESSION ON THE UK*

Power Fluidic systems for the control of liquids and gaseous flows have been adopted for use in radioactive processing plants in the UK. These devices are intrinsically reliable with no mechanical moving parts because they are able to make use of the hydrodynamics of the fluids being controlled. This reliability feature leads to a zero cell maintenance concept and the elimination of mechanical drive/control systems in cell. The first phase of the development work led to their use in the Fast Reactor Reprocessing Plant at Dounreay and the Highly Active Liquor Storage facility at Sellafield. The success of these early developments has led to an extensive development programme for an extended range of applications in the Thermal Oxide Reprocessing Plant and its associated waste treatment facilities at Sellafield. The technology has now been fully demonstrated and adopted for these plants with considerable benefit over a wide range of applications.

431

British Library Electronic Table of Contents (United Kingdom)

We combine establishment-level employment data with trade data by port to examine the impact of accession to the European Economic Community on the spatial distribution of UK manufacturing. We test the predictions from economic geography models of how external trade affects the spatial distribution of employment. We treat accession as a natural experiment which helps mitigate problems of endogeneity. Our results suggest that accession changed the country composition of trade and via the port composition induced an exogenous shock to different locations. In line with theory, we find that better access to export markets and intermediate goods increase employment while increased import competition decreases employment.

2011-01-01

432

Outcome for Gram-negative bacteraemia when following restrictive empirical antibiotic guidelines

British Library Electronic Table of Contents (United Kingdom)

Introduction: Restrictions in prescribing broad spectrum antimicrobials have been part of a strategy to reduce Clostridium difficile cases in the UK in recent years. However, there has been little work on assessing the safety of alternative antimicrobial agents. Methods: We performed an uncontrolled prospective observational survey over a 1-year period to determine the effectiveness and safety of a new antimicrobial stewardship programme in a district hospital in the UK. Results: In total, 227 Gram-negative bacteraemias (203 episodes) occurred in the study period. Guidelines were adequate in 194 of 203 (95%) episodes and 163 episodes (80.2%) received adequate therapy. Patients in the inadequate therapy group had >2-fold increased likelihood of death [odds ratio (OR) = 2.63, 95% confidence ...

2011-01-01

433

Fingerprint testing of contaminated ventilation extract filter systems at Sizewell B

Energy from waste: current progress in Sweden

Sizewell B is Nuclear Electric's latest power station, and the Pressurised Water Reactor (PWR) design on which it is based represents a ''first'' for the UK. One of the integral components of the plant is the heating, ventilation and air-conditioning (HVAC) system, which performs a contamination control and gaseous waste management function for the site. During the commissioning of Sizewell B Power Station the extract systems of the HVAC plant underwent a procedure known as ''fingerprinting''. This entailed the characterisation of the facilities provided to test the filtration plant during its lifetime. The assessment of their adequacy was then used to identify necessary modifications and/or to propose the manner in which future in situ performance testing would be carried out. The paper outlines the basic principles and procedure that was used to ''fingerprint'' test systems during the commissioning of Sizewell B. A specific example is presented to demonstrate the ...

434

Employment, job turnover, and trade in producer services: UK firm-level evidence

Considerable effort worldwide has been put into trying to find the best way to utilise the large amount of energy that we put into our dustbins every day. One of the problems encountered is that the waste collection systems tend to gather together in one place between 400 and 1000 t of the stuff everyday and since it is possible to extract rather more than 2 MW from each tonne, that is a lot of energy for which to find a market. In continental European cities, especially Germany, and Sweden with most of the population living in apartment blocks, and with colder winters than the UK, district heating provides a suitable market. With its milder winters, more diverse housing and cheap gas the UK is not such a fertile ground for district heating. But since the passing of the Energy Act in 1984, there is a steady market in electricity generation with the advantage that the purchase tariffs are published so that income can be accurately calculated.

1988-11-01

435

British Library Electronic Table of Contents (United Kingdom)

Abstract We provide the first firm-level evidence of the impact of the trade in producer services (-offshoring-) on the labour market. Using a new data set from the UK that measures trade in services at the firm level, we find no evidence that importing intermediate services is associated with job losses or greater worker turnover. Using regression to control for observable differences between firms that import service inputs and those that do not, we show that firms that start importing intermediate services experience faster employment growth than equivalent firms that do not. This seems likely to be the result of positive demand shocks, which cause a simultaneous increase in employment, output, and use of imported service inputs.

2011-01-01

436

Chicken runs provide the fuel for Fibrowatt's global ambitions

Britain's dirty deeds at Maralinga

This article reports on the operation of Fibrowatt's third chicken waste-fuelled power plant at Thetford in Norfolk, UK. Details are given of the plant which started operation in October 1998, the chicken litter fuel, the spiral screw fuel feeders, the Detroit Stoker grate and spreader stokers which ensure the fuel is burnt mid-air, the production of fertiliser from the ash, and fluegas emission control using cyclones, a baghouse and lime addition to neutralise acid gas. The economics of the project, and the support for the renewable electricity generation under the UK government's Non-Fossil Fuel Obligation are discussed. A site plan of the Thetford plant and a flow diagram of the process are provided.

2000-08-01

437

Application of 14C analyses to source apportionment of carbonaceous PM2.5 in the UK

Following the United Kingdom's nuclear tests at Maralinga in Australia in the 1960's, the Australian government signed away its rights to claim compensation for decontamination costs in a 1968 agreement. Controversy now rages as the Australian government is claiming pound33 million for this purpose from the United Kingdom to compensate the Maralinga Tjarutja for the loss of access to their traditional lands. They claim that the UK clean-up operation was inadequate and that much plutonium was spread over the land, rather than contained in pits. Measurements of contamination at the site were wrong by a factor of ten according to a 1984 visit when Australian scientists were horrified to realize that an Aboriginal child living near Taranaki could inhale more than 460 millisieverts a year. As ministers from both countries meet in June 1993 the debate is likely to be heated and hotly defended. (UK).

1993-06-12

438

British Library Electronic Table of Contents (United Kingdom)

Determination of the radiocarbon (14C) content of airborne particulate matter yields insight into the proportion of the carbonaceous material derived from fossil and contemporary carbon sources. Daily samples of PM2.5 were collected by high-volume sampler at an urban background site in Birmingham, UK, and the fraction of 14C in both the total carbon, and in the organic and elemental carbon fractions, determined by two-stage combustion to CO2, graphitisation and quantification by accelerator mass spectrometry. OC and EC content was also determined by Sunset Analyzer. The mean fraction contemporary TC in the PM2.5 samples was 0.50 (range 0.27-0.66, n=26). There was no seasonality to the data, but there was a positive trend between fraction contemporary TC and magnitude of SOC/TC ratio and fo...

2011-01-01

439

An evaluation of the UK skills base for toxicologists and ecotoxicologists, with focus on current and future requirements, particularly with regard to the skills required for hazard assessment of chemical substances including nanomaterials

Tests of New Family Gauge Symmetry

Objectives1. To establish the present capacity and capability across all the sectors within the UK for - a) Undertaking research in the areas of toxicology and ecotoxicology and environmental hazard and risk assessment work on chemical subtances including emerging containments (e.g. enginerred nanomaterials); and b) Applying these skills in the policy and regulatory context. 2) The range of chemicals involved should include pharmaceutical and medical products, crop protection agents, biocides, vet [continued...]DescriptionThe aim of this project is to identify the current status of the scientific community, areas of expertise, and identify the gaps in skills, knowledge or recruitment. The project will use a questionnaire approach to obtain this information for all sectors of the business community. The analysis will identify the gaps in provision, and areas where investment is needed in future training and/or recruitment.

2009-01-15

440

Modular symmetry in parametrically excited quantum oscillators

We explore the structure of a new family gauge symmetry U(3) and show its experimental signatures to search for. U(3) gauge bosons obviate an unwelcome deviation of the charged lepton mass formula with the running masses from that with the pole masses. The current structure of this model leads to flavor number violations via exchange of extra gauge bosons. We obtain bounds on the masses of the gauge bosons from rare kaon decay searches and muonium-antimuonium oscillation searches. We propose attractive signatures at LHC and lepton colliders and discuss feasibility of their discovery.

2010-01-01

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441

Glocalisation or globalisation? Travelling discourses of child poverty policy in South Korea

It is shown that when a quantum mechanical oscillator is parametrically excited there are special values of the parameters for which the system will pass periodically through a lattice of coherent states associated with the modular group [Gamma]. It is shown that these [Gamma] transits can be used to determine unknown parameters. A method is given for detecting the transits experimentally and is made possible by the existence of three families of states associated with modular forms that are orthogonal to the lattice. For isotropic states the three families occur in [ital D]-mode systems with [ital D][gt]10, 14, and 26.

1993-11-29

442

British Library Electronic Table of Contents (United Kingdom)

This article examines the interplay between globalising and localising forces occurring in a child welfare reform project in South Korea. Focusing especially on care and education services for children and families provided by the Korean 'Dream Start' programme, which provides comprehensive health, parental involvement and welfare services to low-income children and their families, I discuss its involvement in the process of 'glocalisation'. Drawing on Foucaultian ideas, I conducted a critical discourse analysis of the policy documents of Dream Start. The article concludes by discussing local resistance to the creation of a cosmopolitan child and the dual qualities of inclusion/exclusion inscribed in the Dream Start project.

2011-01-01

443

Asset Prices, Liquidity, and Monetary Policy in an Exchange Economy

British Library Electronic Table of Contents (United Kingdom)

I formulate a model in which money coexists with equity shares on a risky aggregate endowment. Agents can use equity as a means of payment, so shocks to equity prices translate into aggregate liquidity shocks that disrupt the mechanism of exchange. I characterize a family of optimal monetary policies and find that the resulting equity prices are independent of monetary considerations. I also study a perturbation of the family of optimal policies that targets a positive constant nominal interest rate and find that in this case the real equity return includes a liquidity return that depends on monetary considerations.

2011-01-01

444

Social modeling in the transmission of suicidality.

What is the heritable component of spinal deformities in the European sea bass (Dicentrarchus labrax)?

Evidence from twin, adoption, and family studies suggests that there is strong aggregation of suicidal behaviors in some families. By comparison, the role of social modeling through peers has yet to be convincingly established. This paper uses data from four large studies (the WHO/EURO Multicentre Study on Suicidal Behaviour, the WHO/SUPRE-MISS, the CASE study, and the Queensland Suicide Register) to compare the effects of exposure to fatal and nonfatal suicidal behavior in family members and nonfamilial associates on the subsequent suicidal behavior of male and female respondents of different ages. Across all studies, we found that prior suicidal behaviors among respondents' social groups were more important predictors of suicidal behavior in the respondents themselves than previous research had indicated. Community-based suicide attempters in the WHO SUPRE-MISS had higher rates of exposure to prior suicide in nonfamilial ...

2008-01-01

445

British Library Electronic Table of Contents (United Kingdom)

Malformations in farmed fish are a prime research topic as it has a major impact on fish welfare and on the economical value of the product. In this study, the genetic component of spine deformities was estimated in European sea bass, a major species of Mediterranean aquaculture, with the use of a posteriori reconstruction of pedigree with microsatellites. Our population exhibited a very high malformation rate (81%), probably due to intense swimming of fish during pre-growing. The heritability of global spine deformities was evaluated to be 0.21?0.04 on the underlying scale (0.33?0.06 for lordosis, 0.13?0.04 for scoliosis). Deformities scored by an internal or external examination turned out to be genetically the same trait (genetic correlations>0.9), although phenotypic correlations were ...

2009-01-01

446

The ribosome and the mechanism of protein synthesis

Summary of the OA biomarkers workshop 2010 - genetics and genomics: new targets in OA

In virtually all forms of life on earth, proteins in each cell are made according to a genetic blueprint, in the form of DNA. The translation of copies of this genetic blueprint (in the form of messenger RNA) into polypeptides is performed on the ribosome, a highly complex molecular machine composed of RNAs and proteins. To this end, special adaptor molecules called transfer RNAs are lined up by the ribosome in the sequence dictated by the genetic code, such that the amino acids carried by these molecules can be linked into a polypeptide. Several cofactors are involved in these processes, some of which require energy freed up by GTP hydrolysis. Although the ribosome was discovered more than 50 years ago, its structure has only been solved recently by X-ray crystallography. Another technique, cryo-electron microscopy, is starting to contribute toward our understanding of the ribosome's function, by portraying its ...

2006-05-01

447

British Library Electronic Table of Contents (United Kingdom)

On November fourth and fifth 2010 a group of more than 100 international investigators gathered in Atlanta for the second Osteoarthritis (OA) Biomarkers Global Initiative workshop titled ''Genetics and Genomics: New Targets in OA''. The first workshop took place in April 2009 and focused on in vitro (soluble) biomarkers whilst the third and final workshop will take place in 2012 and will focus on imaging biomarkers. The OA Research Society International (OARSI) has organized the workshops. In addition to OARSI, the National Institute of Arthritis, Musculoskeletal and Skin Diseases, the Arthritis Foundation, Amgen, Genzyme, the American Orthopaedic Society for Sports Medicine and Pfizer sponsored the second meeting. It was clear from this meeting that experiments in the genetics, epigenetic...

2011-01-01

448

Predicting the subspecific identity of invasive species using distribution models: Acacia saligna as an example

British Library Electronic Table of Contents (United Kingdom)

Abstract Aim- To explore whether the subspecific genetic entities of Acacia saligna occupy different bioclimatic niches in their native and introduced ranges and whether these niches are predictable using species distribution models (SDMs). Location- Australia, South Africa and the Mediterranean Basin. Methods- Species distribution models were developed in MAXENT using six climatic variables to calculate the climatic suitability of the ranges of A.saligna. We assessed (1) the subspecific niche differences identified by SDMs using measures of niche overlap and model performance; (2) the ability of SDMs to predict the most likely subspecific genetic entities present in South Africa based on comparisons to genetic data; and (3) the ability of SDMs to predict the most likely subspecific geneti...

2011-01-01

449

Molecular phylogeography of the microturbellarian Monocelis lineata (Platyhelminthes: Proseriata) in the North-East Atlantic

British Library Electronic Table of Contents (United Kingdom)

Monocelis lineata is a complex of cryptic species (three in the Mediterranean and one in the Atlantic) widespread in midlittoral habitats. Throughout the range, populations with or without an ocular pigmented shield are found. We investigated the genetic structure of the North-East Atlantic populations with the aim of shedding light on their phylogeography and reconstructing possible patterns of recolonization after the Wrmian glaciation. Fourteen samples were investigated using cytochrome c oxidase subunit I (COI) and 13 by inter-simple sequence repeats (ISSRs). COI did not exhibit a clear pattern of decreased genetic diversity along a latitudinal gradient. Populations from Ferrol (Spain), Doolin (Ireland), and Helsingr (Denmark) showed a higher genetic variability, whereas a reduction in...

2011-01-01

450

Incorporating Traditional Knowledge in an International Regime on Access to Genetic Resources and Benefit Sharing: Problems and Prospects

British Library Electronic Table of Contents (United Kingdom)

The Seventh Meeting of the Conference of the Parties (2004) of the Convention on Biological Diversity established a mandate for the negotiation of an international regime on Access to Genetic Resources and Benefit Sharing arising from their utilization. Negotiations have been proceeding and have entered the final phase. Seven working group meetings have been held to date and there is expectation that an instrument will emerge by the final deadline - the Tenth Meeting of the Conference of the Parties in Nagoya, Japan in October 2010. A key component singled out for inclusion in the international regime relates to the recognition and protection of the rights of indigenous and local communities (ILCs) over their traditional knowledge (TK) associated with genetic resources. The Ninth Meeting o...

2010-01-01

451

Human cDNA mapping using fluorescence in situ hybridization

Genetic fidelity of long-term micropropagated shoot cultures of vanilla (Vanilla planifolia Andrews) as assessed by molecular markers

Genetic mapping is approached using the techniques of high resolution fluorescence in situ hybridization (FISH). This technology and the results of its application are designed to rapidly generate whole genome as tool box of expressed sequence to speed the identification of human disease genes. The results of this study are intended to dovetail with and to link the results of existing technologies for creating backbone YAC and genetic maps. In the first eight months, this approach generated 60--80% of the expressed sequence map, the remainder expected to be derived through more long-term, labor-intensive, regional chromosomal gene searches or sequencing. The laboratory has made significant progress in the set-up phase, in mapping fetal and adult brain and other cDNAs, in testing a model system for directly linking genetic and physical maps using FISH with small fragments, in setting up a database, and in establishing the ...

1993-03-04

452

British Library Electronic Table of Contents (United Kingdom)

Occurrence of genetic variants during micropropagation is occasionally encountered when the cultures are maintained in vitro for long period. Therefore, the micropropagated multiple shoots of Vanilla planifolia Andrews developed from axillary bud explants established 10 years ago were used to determine somaclonal variation using random amplified polymorphic DNA (RAPD) and intersimple sequence repeats markers (ISSR). One thousand micro-plants were established in soil of which 95 plantlets (consisting of four phenotypes) along with the mother plant were subjected to genetic analyses using RAPD and ISSR markers. Out of the 45 RAPD and 20 ISSR primers screened, 30 RAPD and 7 ISSR primers showed 317 clear, distinct and reproducible band classes resulting in a total of 30 115 bands. However, no ...

2007-01-01

453

Genetic factors for resistance to diet-induced obesity and associated metabolic traits on mouse chromosome 17

British Library Electronic Table of Contents (United Kingdom)

Obesity is associated with increased susceptibility to dyslipidemia, insulin resistance, and hypertension, a combination of traits that comprise the traditional definition of the metabolic syndrome. Recent evidence suggests that obesity is also associated with the development of nonalcoholic fatty liver disease (NAFLD). Despite the high prevalence of obesity and its related conditions, their etiologies and pathophysiology remains unknown. Both genetic and environmental factors contribute to the development of obesity and NAFLD. Previous genetic analysis of high-fat, diet-induced obesity in C57BL/6J (B6) and A/J male mice using a panel of B6-ChrA/J/NaJ chromosome substitution strains (CSSs) demonstrated that 17 CSSs conferred resistance to high-fat, diet-induced obesity. One of these CSS st...

2009-01-01

454

Genetic and environmental interactions determine plant defences against herbivores

British Library Electronic Table of Contents (United Kingdom)

Summary 1. Plants express multiple defensive traits, but little is known about the genetic stability and phenotypic plasticity of these traits in nature. To investigate sources of variation and their potential ecological consequences for herbivores, we combined field observations of cyanogenic lima bean with laboratory experiments. 2. Field studies in South Mexico revealed a distinct variability of cyanogenic traits within and among wild lima bean populations. To differentiate among genetic variation and the impact of ambient conditions on plant phenotypes, we used seed grown plants as well as clones propagated from high (HC) and low cyanogenic (LC) wild type plants. 3. In growth chamber experiments, we cultivated plants under three intensities each of drought and salt stress, nutrient sup...

2011-01-01

455

Estimates of quantitative genetic parameters of immunological traits in the chicken.

Borderline personality traits and adult attention-deficit hyperactivity disorder symptoms: A genetic analysis of comorbidity

Three in vivo assays were used to measure the immunocompetence of chickens in two generations of a selection experiment. The obtained data were used to estimate the variance components for sire and dam for antibody production to Pasteurella multocida and Mycoplasma gallisepticum vaccines, for T-cell-mediated immunity evaluated by a phytohemagglutinin wing web assay, and for clearance of foreign particles from the circulatory system. Heritabilities of and genetic correlations among these immunological traits were calculated from the sire variance components. Heritability estimates of the immunological traits based on the sire component of variance ranged from .06 to .53, and genetic correlations among immunological traits were generally negative. PMID:1956847

1991-10-01

456

British Library Electronic Table of Contents (United Kingdom)

Abstract Previous research has established the comorbidity of adult Attention-Deficit Hyperactivity Disorder (ADHD) with different personality disorders including Borderline Personality Disorder (BPD). The association between adult ADHD and BPD has primarily been investigated at the phenotypic level and not yet at the genetic level. The present study investigates the genetic and environmental contributions to the association between borderline personality traits (BPT) and ADHD symptoms in a sample of 7,233 twins and siblings (aged 18-90 years) registered with the Netherlands Twin Register and the East Flanders Prospective Twin Survey (EFPTS) . Participants completed the Conners' Adult ADHD Rating Scales (CAARS-S:SV) and the Personality Assessment Inventory-Borderline Features Scale (PAI-BO...

2011-01-01

457

Association between chemical and genetic variation in Calophyllum inophyllum, a medicinally important tree of the Western Ghats of India

British Library Electronic Table of Contents (United Kingdom)

The objective of the present work is to study the chemical variation in Calophyllum inophyllum growing along the Western Ghats of India. Contents of dipyranocoumarins (inophyllums) in C.?inophyllum were determined to assess whether they could be used as a taxonomic marker for C.?inophyllum. This study also aims to establish inter simple sequence repeat (ISSR) markers that can be used to study genetic variation within the species and explore correlation between ISSR and chemical markers. The contents of dipyranocoumarins were estimated in seeds collected from 20 locations. Leaves from plants at the same 20 locations were assayed for ISSR variation. A dendrogram based on Nei?s genetic distance as well as principal component analysis based on dipyranocoumarins and ISSR variation clustered pla...

2011-01-01

458

An integrated genome research network for studying the genetics of alcohol addiction

British Library Electronic Table of Contents (United Kingdom)

Abstract Alcohol drinking is highly prevalent in many cultures and contributes to the global burden of disease. In fact, it was shown that alcohol constitutes 3.2% of all worldwide deaths in the year 2006 and is linked to more than 60 diseases, including cancers, cardiovascular diseases, liver cirrhosis, neuropsychiatric disorders, injuries and foetal alcohol syndrome. Alcoholism, which has been proven to have a high genetic load, is one potentially fatal consequence of chronic heavy alcohol consumption, and may be regarded as one of the most prevalent neuropsychiatric diseases afflicting our society today. The aim of the integrated genome research network -Genetics of Alcohol Addiction--which is a German inter-/trans-disciplinary life science consortium consisting of molecular biologists,...

2010-01-01

459

for wheelie bins.\\

... stock code: BOXfloral description: sunflower x 4, blue skies x 4, lavender 3, lupins x 3, poppy field 3, meadow x 3 Introductory Offer price: 𧵎.00 per box, plus delivery normal price 𧵘 UK only Poppy field box add to basket Lupins box add to basket Lavender box add to basket ...

460

for wheelie bins.\\

Vortex control of safety enclosures

... stock code: BOXfloral description: sunflower x 4, blue skies x 4, lavender 3, lupins x 3, poppy field 3, meadow x 3 price: 𧵎.00 per box, plus delivery UK only Poppy field box add to basket Lupins box add to basket Lavender box add to basket Sunflower box add to ...

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461

Vocational rehabilitation services for patients with cancer: design of a feasibility study incorporating a pilot randomised controlled trial among women with breast cancer following surgery

The vortex amplifier controller has no moving parts and therefore it can have extremely high reliability and avoid the maintenance problems associated with contaminated equipment. The vortex amplifier and its application to ventilation control of radioactive enclosures is described. Reverse purge vortex amplifier ventilation system control is also discussed. (U.K.).

462

The size of the hole in the ozone layer | Environment | guardian.co.uk

BackgroundDue to improvements in cancer survival the number of people of working age living with cancer across Europe is likely to increase. UK governments have made commitments...Full Text Available

463

The potential of non-toxic tannins to improve the utilisation of nitrogen compounds in grass silage by ruminants

... Space weather is the biggest driver of ozone depletion and much else we are only beginning to understand. Solar Cycle 24 may turn out to be weak in terms of sun spot count but the amount of energy delivered by CME/SPE will probably not be. Remember that the Carrington Event in 1859 happened during a cycle with a lowish sun spot count. Recommend (1) Report abuse ...

464

Thailand: utilisation programme set for massive expansion

DescriptionInefficient utilisation of dietary nitrogen (N) by animals results in the excretion of N in varying forms, with adverse environmental consequences. Grass silage is a major component of the diet of ruminant livestock in the UK, but the protein in silage is very highly degraded as a result of the ensilage process. This results in poor capture of the silage N by rumen microbes leading to overall poor utilisation for the synthesis of milk or meat. As a result, significant quantities of dietary N are [continued...

2006-01-31

465

Sustainable phosphorous fertilisation of potatoes (Potato CHIPS)

The US$360 million project to increase gas supplies to Eastern and Southern Thailand is discussed, and the use of international competitive bidding to purchase the line pipe and other facilities is reported. The government approved proposal for a gas fired combined-cycle power station and gas separation plant are discussed. (UK).

1991-11-01

466

DescriptionThis project has two independent aims: (1) to investigate the use of struvite as an alternative to chemical P fertilisers and (2) to develop an oligonucleotide microarray to monitor the P status of the potato crop. The UK horticultural and agricultural industries rely on large inputs of phosphate (P) fertilisers to maintain crop yields and quality. However, the use of non-renewable, chemical P fertilisers is unsustainable, and the alternatives to chemical P-fertilisers must be identified as an [continued...

2008-01-31

467

Scots seek soft path

Religious groups have too much freedom to discriminate | Evan Harris | Comment is free | guardian.co.uk

Energy policy is discussed, with particular reference to Scotland. The plans for nuclear power are analyzed in comparison with developments in coal mining, use of oil and gas and other possible energy sources such as wind and wave power. Arguments against the development of nuclear power are raised on grounds of economics, employment potential, and problems of waste disposal. (U.K.).

1979-03-01

468

Radioactive and stable isotope geology

... Wanting to help a charity is commendable but the main focus of generosity should be the people in front of you, not your choice of spiritual overlord - especially so if the group is being funded with money from taxpayers. Recommend? (44) Report abuse | Link ...

469

Quark-parton picture of the cumulative production

Aimed at post-graduate and post-doctoral researchers in geochemistry, this book reflects the rapid changes in the applications of radioactive and stable isotope analysis to a range of geological and geochemical problems. Isotropic chemistry and methods used in mass spectroscopy are discussed initially. The second section deals with radiometric dating methods. The role of isotopes in climate and environmental research is also explored. The book closes with a section on extra-terrestrial matter, geothermometry and the isotopic geochemistry of the Earth`s lithosphere. (UK).

1997-10-01

470

Preparation of radiopharmaceuticals and labelled compounds using short-lived radionuclides

The quark structure of constituent nucleons is considered by a qualitative comparison of features of different models with experimental data with respect to cumulative meson production. It is shown that the fluctuation of the density of nuclear matter, ie the creation and disintegration of a short lived few-nucleon correlation (flucton), is a type of the quasi-resonance formation in the nucleus which exists without any connection with the incident particle. The cumulative production in the region under investigation is mostly the result of a Regge type dissociation of the flucton. (U.K.).

471

Policy background - Department of Energy and Climate Change

The subject is reviewed in sections, entitled: introduction (historical); sources of short-lived radionuclides; carbon-11; nitrogen-13; oxygen-15; fluorine-18; bromine-77; iodine-123; astatine-211; other radionuclides (including Ga-67, Ga-68, In-111, In-113m, Tc-99m, and Pb-203). (U.K.).

472

...this page document analysis carried out during the policy development of the CRC Energy Efficiency Scheme. policy, background, carbon, reduction,...commitment, energy efficiency, CRC, Policy background Spending Review Announcement In the October 2010 Spending Review, the UK Government announced that the CRC ... Revenue from the sale of CRC allowances, totalling ٟ billion a year by 2014/15, will be used to support ... The implications of this announcement for CRC are: In order to clarify the price signal to participants and to support the public ...

473

Pipe crawlers

Ozone hazards incurred in #gamma#-plant operation

The patent concerns pipe crawlers, i.e. apparatus capable of moving along the bores of pipes and tubes. Pipe crawlers are employed for conveying inspection equipment along the bores of pipes and tubes. The pipe crawler comprises a piston and assembly system, which controls the movement of the crawler and supports the assembly centrally within the bore of the pipe or tube. (UK).

1984-11-29

474

Nuclear power generation. Chapter 14

The irradiation of air produces some toxic gases such as ozone, nitric oxide, nitrogen dioxide, nitrogen trioxide, nitrogen tetroxide, nitric anhydride and nitrous oxide. Of these gases, ozone is the most important because of its toxicity and may be produced in such quantities as to constitute a health hazard within the irradiation room. The toxicity, and explosive characteristics of ozone and quantitative aspects of ozone production are discussed and ventilation requirements considered. (U.K.).

475

Monoclonal antibody imaging in malignant and benign gastrointestinal diseases

As part of a handbook on the efficient use of energy a chapter is included which is intended to give an appreciation of the principles and problems involved in the generation of nuclear power. The subject is discussed under the following headings: introductory nuclear physics; basic reactor physics; thermal reactors; fast reactors; fuel reserves and utilization; environmental considerations; nuclear fusion. (U.K.).

1975-01-01

476

Localization of an anti-tumour monoclonal antibody in human tumour xenografts: kinetic and quantitative studies with the 791T/36 antibody

The "1"3"1I-labelled monoclonal antibodies 791T/36 and 79IT/36 Fab fragments have been evaluated in the imaging of patients with colorectal cancer, with benign colorectal tumours, and with malignant tumours of other parts of the gastrointestinal tract. The results of clinical imaging have been carefully correlated with clinical findings and direct measurement of the preferential uptake of antibody by the tumours. (UK).

477

Investigation into the fatigue behaviour of wood laminates for wind energy converter blade design

Studies have been performed with an anti-osteogenic sarcoma monoclonal antibody 791T/36 and human tumour xenografts to examine some of the quantitative and kinetic aspects of tumour localization. The influence of variations in tumour size and site and antibody dose on the extent and rate of specific antibody localization have been examined, together with the site of intratumoural deposition of the antibody. (UK).

478

International water power and dam construction yearbook 1996

A thesis is presented on improving the understanding of the fatigue properties of wood and fatigue failure mechanisms in the design of wind turbine blades. Three main areas were researched: the effect of R ratio on fatigue life, the effect of moisture on fatigue life and the development of cumulative damage laws. Tests were carried out on mainly four-ply laminates. Recommendations to future work are outlined. (U.K.).

1987-01-01

479

In a spin over power fluidics

This document draws together data on hydroelectric power generation and dam construction for 1996. Machinery such as turbines and hydroelectric generators are listed together with their manufacturers. Contact addresses for international organizations concerned with water power are listed. Listings are also given for hydro resources worldwide, and the global distribution of pumped-storage plants, dams and hydroelectric plants. Company data is also listed providing a buyer`s guide for 1996. (UK)

1996-12-31

480

IDEAS: Sociological Research Online, Sociological Research Online

In response to severe maintenance problems caused by the highly corrosive toxic and radioactive substance used in the nuclear reprocessing industry, AEA Technology (formerly the United Kingdom Atomic Energy Authority) has developed a series of power fluidics devices with no moving parts. These maintenance-free devices are described in this article which also explores applications in fields outside their original brief. (UK).

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481

...] Responsibility and the Big Society by Antje Bednarek [Downloadable!] Friendship Dynamics Between Emotions and Trials by Paola Rebughini [Downloadable!] On Friendship, Equality and Introductions: Comparing English and German Regimes of Manners and Emotions by Cas Wouters [Downloadable!] Fees, Funding and Overseas Study: Mobile UK Students and Educational Inequalities by Rachel Brooks & Johanna Waters [Downloadable!] The Subject of Functional Foods: Accounts of Using Foods Containing Phytosterols by Kate Weiner [Downloadable!] Paradoxes and Pitfalls in ...

482

Heat transfer

GM mosquito wild release takes campaigners by surprise - SciDev.Net

Heat transfer has emerged as a leading-edge technology supporting the rapid pace of developments in science and engineering ranging from energy production to electronic cooling. Subjects covered at the 6th UK National Conference on heat transfer held at Edinburgh from 15-16 September 1999 include: convection; boiling and evaporation; condensation; numerical techniques; heat exchangers; radiation and combustion; conduction; two-phase flow and heat transfer augmentation. Fifteen of the papers are abstracted here.

1999-07-01

483

GM Mosquito Wild Release Takes Campaigners by Surprise

... The male GM mosquitoes mate with normal females to produce larvae that die unless the antibiotic tetracycline is present. In tetracycline's absence an enzyme accumulates to a toxic level, killing the larvae. The developers hope the strategy could be combined with other mosquito control methods to reduce transmission in dengue-prone areas. Ricarda Steinbrecher, a geneticist and co-director of EcoNexus -a UK-based non-profit research organisation -expressed surprise ...

484

... The male GM mosquitoes mate with normal females to produce larvae that die unless the antibiotic tetracycline is present. In tetracycline's absence an enzyme accumulates to a toxic level, killing the larvae. The developers hope the strategy could be combined with other mosquito control methods to reduce transmission in dengue-prone areas. Ricarda Steinbrecher, a geneticist and co-director of EcoNexus - a UK-based non-profit research organization - ...

485

Food irradiation

Evaluate the Health Potential of Fruit & Vegetable Snack Products (EFH 11)

A brief article examines the controversy over food irradiation regarding the wholesomeness of irradiated food, its microbiological safety, loss of vitamins and changes in flavour. The benefits of food irradiation are also outlined including the destruction of certain food-borne pathogens and the prolongation of the shelf-life of food by killing pests and delaying the deterioration process. (UK).

1987-02-01

486

Environmental effects and energy efficiency in building design - a green building approach. Pt. 3. Design case studies

DescriptionDespite the growing recognition of the important part fruit and vegetables can play in helping prevent a number of diseases, health and nutrition experts are concerned about the low consumption of fruits and vegetables in the UK. The principal aim of this project is to improve consumer dietary consumption of fruit and vegetables by developing novel snack foods based on the fruit and vegetable materials using extrusion processing.

2005-01-31

487

Environmental effects and energy efficiency in building design - a green building approach. Pt. 2. Basic data for environmental effects

This is the third of a series of research reports which builds on the previous contents which dealt with energy efficiency techniques and minimizing the environmental effects of building materials. It presents some specifications for house types and gives built examples of energy efficient homes in Europe. (UK)

1993-12-31

488

Environmental effects and energy efficiency in building design - a green building approach. Pt. 1. Energy efficiency techniques

A research report presents the basic data required when designing a building with minimal environmental impacts. Topics covered include the energy consumption of building elements during their lifetime, the environmental implications linked to the extraction and processing of building material and the energy consumed in buildings by the occupants. (UK)

1993-12-31

489

Environmental and thermal efficiency benefits by use of RDF

A research report describes the energy efficiency techniques to be employed in designing a building which is ``green``. Topics covered include building fabric performance, ventilation and infiltration, passive solar design, heating systems and controls, hot and cold water provision, lighting and electrical appliances. (UK)

1993-12-31

490

Electricity supply in the United Kingdom. Brief details and statistics

This paper presents a brief overview of refuse derived fuel (RDF) processing systems, and the different types of RDF. The quality of RDF, combustion of RDF in fluidized beds, and moving grate reactors, operating conditions, emissions (sulphur dioxide, nitrogen oxides, carbon monoxide and hydrogen chloride) and thermal efficiency are discussed. (UK).

1994-05-01

491

Dounreay: an alternative development

Statistical detail is given of the electricity generation and transmission systems in the UK. Breakdown by type of station, by fuel and the proportion generated by others apart from the generating or area boards is presented. Figures are provided for the various high voltage transmission lines in terms of route and circuit length as well as the number of towers and the capacity of mains transformers.

1987-06-01

492

Domestic radon exposures in the UK

With the Government decision to phase out the Fast Reactor at Dounreay there is a need to find alternative employment in the area. Traditionally Caithness is an area of farming, fishing and tourism which could be damaged if Dounreay were to be made a nuclear waste repository. The suggestion is that Dounreay should become a centre for research, development and subsequent manufacture of renewable energy sources and devices to harness renewable energy. The Scottish coastline has potential for wind and wave power developments and this could lead to a whole industry in the future. (UK).

1991-01-01

493

Decommissioning and abandonment of onshore pipelines

Radon in the home is the main source of exposure to ionising radiation for most people. In 1990 the National Radiological Protection Board issued revised advice to the United Kingdom Government on standards of protection against radon in the home. A description is offered of the survey work being undertaken by the Board which includes radiation measurements of thousands of homes in the United Kingdom. (author).

1991-09-01

494

Current ventilation and air conditioning systems and strategies

The UK Pipelines Safety Regulations require the pipeline operator to ensure that a pipeline, once decommissioned, does not become a source of danger. Elsewhere, Regulatory Authorities require consideration of the possible issues which pipeline decommissioning may raise. This paper considers current practice with respect to pipeline decommissioning and abandonment, and sets out the range of factors which the operator must take into account. (author)

1999-07-01

495

Contact with HIV prevention services highest in gay and bisexual men at greatest risk: cross-sectional survey in Scotland

The report examines common ventilation and air conditioning systems and strategies for both domestic and commercial buildings; and covers issues such as energy conservation, indoor air quality and occupant comfort. Drawing data from many countries in Europe and the United States of America, various natural, mechanical and air conditioning systems were compared using criteria such as climate, level of occupant interaction, and level of system comfort. This classification system is evaluated and seen as a valuable framework for further research. (U.K.)

1994-02-01

496

Coal liquefaction provides increased security of oil supply. La licuefaccion del carbon ofrece una mayor independencia del suministro petrolero

BackgroundMen who have sex with men (MSM) remain the group most at risk of acquiring HIV in the UK and new HIV prevention strategies are needed. In this paper, we examine what contact...Full Text Available

497

The UK's reserves of crude oil could last another 300 years. This is the result it is hoped to obtain from tests currently being carried out in British Coal's liquefaction project of which the objective is to produce a high quality liquid fuel from coal. 1 fig.

1991-07-01

498

CCMAP Contract

Assessing predictive skill of models to optimise crop management and design

DescriptionCEH - Quest CCMAP see http://quest.bris.ac.uk/research/themes/CCMAP.html CCMAP (Climate-carbon modelling, assimilation and prediction) Leader: Dr. Eleanor Blyth (CEH, Wallingford) Overview and Goals CCMAP is one of QUEST's Theme 1 projects and is about to be commissioned to the Centre for Ecology and Hydrology at Wallingford. The Principal Investigator will be Dr. Eleanor Blyth, with subcontracts to the Universities of Bristol (Dr. Wolfgang Knorr, Earth Sciences and QUEST; Andy Ridgw [continued...

499

Applying fluidics to reactor safety and reprocessing

DescriptionAn ability to foresee impacts on output is invaluable to any industry; good prediction is the basis of good management. Many research models can predict crop performance, but the skill (used here to include accuracy, precision, facility and credibility) of these predictions is rarely assessed, so is not well known. The only research model successfully adopted for practical purposes in the UK is the Broom's Barn Beet Model. Thus we propose here, research to assess and publish the skill of the [continued...

2004-01-30

500