WorldWideScience

Sample records for ten case studies

  1. Frictional amyloidosis in Oman - A study of ten cases

    Directory of Open Access Journals (Sweden)

    Mysore Venkataram

    2002-01-01

    Full Text Available Macular amyloidosis is an important cause for cutaneous pigmentation, the aetiology of which is poorly understood. Friction has recently been implicated the causation of early lesions, referred to as frictional amyloidosis. Confirmation of diagnosis by the detect on of amyloid using histochemical stains is inconsistent. Ten patients with pigmentation suggestive of macular amyloidosis were studied with detailed history, clinical examination, biopsy for histochemistry and electron microscopy. Nine out of ten patients had a history of prolonged friction with various objects such as bath sponges, brushes, towels, plant sticks and leaves. Amyloid was demonstrated by histochemical staining in only six out of ten cases. In the remaining four cases, amyloid was detected by electron microscopy. These consisted of aggregates of non-branching, extracellular, intertwining fibres measuring between 200-500 nm in length and between 20-25 nm in diameter. The study confirms the role of friction in the causation of this condition. Histochemical stains are not always successful in the detection of amyloid and electron microscopy is helpful for confirming its presence. The term frictional amyloidosis aptly describes the condition.

  2. Keys to success: Ten case studies of effective weatherization programs

    Energy Technology Data Exchange (ETDEWEB)

    Brown, M.A.; Berry, L.G.; Kolb, J.O.; White, D.L. [Oak Ridge National Lab., TN (United States); Kinney, L.F.; Wilson, T. [Synertech Systems Corp., Syracuse, NY (United States)

    1993-11-01

    In 1990, DOE initiated a nationwide evaluation of its Weatherization Program, with assistance from Oak Ridge National Laboratory and an advisory group of 40 weatherization professionals, program managers, and researchers. The evaluation is comprised of three impact studies covering the Program`s major market segments: Single-family homes, mobile homes, and dwellings in small (2 to 4-unit) multifamily buildings (the Single-Family Study), Single-family homes heated primarily with fuel oil (the Fuel-Oil Study), and Dwellings in buildings with five or more units (the Multifamily Study). The Single-Family Study, the subject of this report, is a critical part of this coordinated evaluation effort. Its focus on single-family dwellings, mobile homes, and dwellings in small multifamily buildings covers 83% of the income-eligible population and 96% of the dwellings weatherized during Program Year 1989. The first phase of the Single-Family Study involved the analysis of a massive data base of information collected from 368 local weatherization agencies and 543 electric and gas utilities. This analysis resulted in energy-saving and cost-effectiveness estimates for the Weatherization Program and the identification of a set of ten high-performing agencies located throughout the country. The second phase, which is the subject of this report, involves a ``process`` evaluation of these ten high performers, aimed at identifying those weatherization practices that explain their documented success.

  3. Adolescent cancer patients' perspectives on their educational experiences: Ten case studies

    Science.gov (United States)

    Searle, Nancy Smith

    The goal of this study was to explore the educational experiences of adolescent cancer patients in treatment for cancer and enrolled in hospital, homebound, or community schools. The incidence of students who have or had cancer is becoming more prevalent in schools today because of increases in the population, the incidence rate of cancer, and the survival rate of cancer. The number of students surviving cancer has increased over 41% in the past ten years and underscores the importance of assuring an excellent education to children and adolescents with cancer so that they may enjoy a good quality of life as long-term survivors. This study explored the educational experiences of students who were adolescent cancer patients and identified educational and psychosocial issues important to their success. The goal of this research effort was to provide educators and medical staff with a deeper understanding of the unique psychoeducational needs of this population and to provide a foundation for developing ideas for improving the educational programs and support available to students who continue their middle and high school education while undergoing treatment for cancer. Participants included ten cancer patient whose mean age at onset of disease was 13.8 +/- 1.7 years, and mean age at interview was 15.2 +/- 1.8 years. The researcher conducted individual, in-depth, ethnographic interviews of students, and one parent and one teacher of each student. Case studies of the students included extensive dialogue of each of the contributing participants. An analysis of the case studies was conducted by coding emerging themes so that topics could be fully explored and compared between individuals, groups of individuals, and educational settings to identify the meaning that these students placed on the educational and psychosocial issues that they voiced as important. Advantages and disadvantages of each educational situation, homebound, hospital school, and community school, were compared. Psychosocial issues related to education were discussed. Additional findings included information about student computer use and information gathering, and the effects of cancer treatment on student interest in science and future occupational plans.

  4. The acute radiation syndrome: A study of ten cases and a review of the problem

    Energy Technology Data Exchange (ETDEWEB)

    Hempelmann, L.H.; Lisco, H.

    1950-03-17

    In this report ten cases of acute radiation syndrome are described resulting from two accidents occurring at the Los Alamos Scientific Laboratory of unique nature involving fissionable material. These cases are described in considerable detail. The report comprises ten sections. This volume, part II of the report, is comprised of sections entitled: (1) the Biological Basis for the Clinical Response seen in the Acute radiation Syndrome, (2) Clinical Signs and Symptoms, (3) Discussion of Hematological Findings, (4) Chemistry of the Blood and Urine, (5) Discussion of Pathological Findings, and (6) Reconsiderations of the Calculated Radiation Doses in Terms of the Observed Biological Response of the Patients. This report was prepared primarily for the clinician who is interested in radiation injuries and therefore emphasis has been placed on the correlation of clinical and pathological changes with the type of cytogenetic change known to be produced by ionizing radiation.

  5. Making a difference: Ten case studies of DSM/IRP interactive efforts and related advocacy group activities

    Energy Technology Data Exchange (ETDEWEB)

    English, M.; Schexnayder, S.; Altman, J. [Tennessee Univ., Knoxville, TN (United States). Energy, Environment and Resources Center; Schweitzer, M. [Oak Ridge National Lab., TN (United States)

    1994-03-01

    This report discusses the activities of organizations that seek to promote integrated resource planning and aggressive, cost-effective demand-side management by utilities. The activities of such groups -- here called energy efficiency advocacy groups (EEAGs) -- are examined in ten detailed am studies. Nine of the cases involve some form of interactive effort between investor-owned electric utilities and non-utility to develop policies, plans, or programs cooperatively. Many but not all of the interactive efforts examined are formal collaboratives. In addition, all ten cases include discussion of other EEAG activities, such as coalition-building, research, participation in statewide energy planning, and intervention in regulatory proceedings.

  6. Understanding Place-Value: A Case Study of the Base Ten Game

    Science.gov (United States)

    Broadbent, Andrea

    2004-01-01

    In this article, the author reports findings from a project designed to explore approaches for improving students' mathematical learning outcomes in relation to the base ten number system. The project explored the role of a commonly used teaching activity, referred to in the project as the "base ten game," in developing children's understanding of…

  7. PURPA Resource Development in the Pacific Northwest : Case Studies of Ten Electricity Generating Powerplants.

    Energy Technology Data Exchange (ETDEWEB)

    Washington State Energy Office.

    1990-07-01

    The case studies in this document describe the Public Utilities, Regulatory Policies Act (PURPA) development process for a variety of generating technologies. Developer interactions with regulatory agencies and power purchasers are described in some detail. Equipment, installation, and maintenance costs are identified; power marketing considerations are taken into account; and potential environmental impacts, with corresponding mitigation approaches and practices are summarized. The project development case studies were prepared by the energy agencies of the four Northwest states, under contract to the Bonneville Power Administration.

  8. Business Models for e-Health: Evidence from Ten Case Studies

    OpenAIRE

    Kimble, Chris

    2015-01-01

    An increasingly aging population and spiraling healthcare costs have made the search for financially viable healthcare models an imperative of this century. The careful and creative application of information technology can play a significant role in meeting that challenge. Valuable lessons can be learned from an analysis of ten innovative telemedicine and e-health initiatives. Having proven their effectiveness in addressing a variety of medical needs, they have progressed b...

  9. A clinical study on ten cases of superior mesenteric arterial occulusion

    International Nuclear Information System (INIS)

    A total of 10 cases of acute superior mesenteric arterial occulusion (SMAO) treated in our department in a previous 11-year period were divided into the survival (n=4) and death (n=6) groups and studied for the diagnosis, treatment, and postoperative management. An averaged age of them was as high as 81 years. All the patients had some cardiovascular disorders as underlying diseases, and seven patients of them had atrial fibrillation. The time from the onset of SMAO to the treatment ranged from 4 to 96 hours, in that no significant difference was noted between the survival and death groups. Contrast enhanced abdominal CT was conducted preoperatively in all the patients. It was retrospectively considered that preoperative diagnosis had to be made by the CT scans in eight of them who had developed occulusion at the center of the superior mesenteric artery. Except one patient who could be treated by interventional radiology (IVR) using a balloon-tip catheter, the remaining nine patients underwent laparotomy and six out of the nine patients underwent the resection of massive intestines. Seven patients overcame postoperative acute phase, however, only four of them were able to recover their social activities. In order to improve the prognosis of the disease, we are required not only to avoid massive intestinal resection by making early diagnosis, but also to conduct long-term postoperative intensive therapies including those for underlying diseases as well as prevention of recurrence and nutritional management. (author)

  10. A ten year study of STD Cases in an urban clinic in Calcutta

    Directory of Open Access Journals (Sweden)

    Ghosh Sadhana

    1994-01-01

    Full Text Available Total 16440 patients attended the STD clinic during the 10 years period of study from 1984 to 1993. From 1988 number of STD caes were gradually decreasing probably due to less promiscuity in fear of AIDS and different measures taken to prevent transmission of HIV infection. But it does not lessen the importance of STD control, because syphilis is still prevalent (8% with congenital syphilis. Peak in the incidence of chancroid (15% is alarming as this may lead to increased transmission of HIV infection in near future. Male unmarried constituted the bulk of STD sufferers (44% and married males (34%, while female unmarried and married patients were 1% and 20% respectively, 5.7% of antenatal mothers were strongly seroreactive for syphilis. Therefore all antenatal mothers should be screened for STD and routine serological test for syphilis should be done.

  11. A Study of Accommodations Provided to Handicapped Employees by Federal Contractors. Final Report. Volume II: Ten Case Studies.

    Science.gov (United States)

    Berkeley Planning Associates, CA.

    A series of 10 case studies was conducted as part of a 20-month nationwide study of the accommodations provided to handicapped employees by federal contractors. During the course of the project, case study visits were made to the following firms: the Dow Chemical Company; E. I. DuPont de Nemours and Company; Hewlett-Packard; IBM Corporation;…

  12. Childhood herpes zoster: A clustering of ten cases

    Directory of Open Access Journals (Sweden)

    Prabhu Smitha

    2009-01-01

    Full Text Available Herpes zoster occurs due to reactivation of the latent varicella zoster virus and is usually a disease of the elderly. Childhood herpes zoster is believed to be rare, though recent studies suggest increasing incidence in children. Here we report ten cases of childhood herpes zoster, seven of which occurred within a short span of six months, at a tertiary care level hospital in Pokhara, Nepal. Only three of the ten children reported previous history of varicella infection and none was immunized against varicella. Though childhood herpes zoster accounted for less than 1% of the total zoster cases in the past, recent reports show an increase in the number of cases in apparently healthy children. So far, no studies have been done linking childhood herpes zoster with HIV, though there are many studies linking it with other immunocompromised conditions.

  13. Lifeline electric rates and alternative approaches to the problems of low-income ratepayers. Ten case studies of implemented programs

    Energy Technology Data Exchange (ETDEWEB)

    1980-07-01

    Program summaries, issue developments, governmental processes, and impacts are discussed for 10 case studies dealing with lifeline electric rates and alternative approaches to the problems of low-income ratepayers, namely; the Boston Edison rate freeze; the California lifeline; Florida Power and Light conservation rate; the Iowa-Illinois Gas and Electric small-use rate; the Maine demonstration lifeline program; the Massachusetts Electric Company A-65 rate; the Michigan optional senior citizen rate; the Narragansett Electric Company A-65 SSI rate; the Northern States Power Company conservation rate break; and the Potomac Electric Power Company rate freeze. (MCW)

  14. Large-Scale Curriculum Change in a System of Ten Indonesian Medical Schools: A Case Study of Educational Innovation.

    Science.gov (United States)

    Blizard, Peter J.; And Others

    1980-01-01

    A case history is given of major curriculum changes in a system of medical schools, involving 260 departments. It is proposed that this history clarifies selected aspects of the theoretical literature on educational innovation and diffusion and on staff development program planning and provides some practical guidelines. (MSE)

  15. Subtotal Hemispherectomy, Report of Ten Cases

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    N. O. Ameli

    1960-01-01

    Full Text Available 10 cases submitted to subtotal hemispheretomy are discussed. In selected group of infantile hemiplegia where epilepsy and behaviour disturbances are pr~sent, and investigations prove that the other hemisphere is farly normal, thts operation is of greatt benefit. Ne,vertheless long follow-up of these cases IS necessary before a final judgement can be passed. Age should.be no barrier to selection, as those of 18 - 25 have benefited as much as young children

  16. Primary lymphoma of the central nervous system: a clinical-pathological and immunohistochemical study of ten autopsy cases Linfoma primário do sistema nervoso central: estudo clínico-patológico e imuno-histoquímico de dez casos de necropsia

    OpenAIRE

    Henrique Costa; Marcello Franco; Myriam Dumas Hahn

    2006-01-01

    CONTEXT: Primary central nervous system lymphomas (PCNSL) are a rare subgroup of lymphomas generally associated with HIV and EBV. OBJECTIVE: To study ten autopsy cases of PCNSL, to describe the neuropathological findings, to characterize the phenotype of the neoplastic cells, to detect EBV in the lesion and to compare the findings with the clinical and laboratory data of the patients. METHOD: The clinical, histological and immunohistochemical data of ten cases of PCNSL, eight cases from patie...

  17. Drug-induced Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS-TEN overlap: A multicentric retrospective study

    OpenAIRE

    M Barvaliya; Sanmukhani, J.; Patel, T.; N Paliwal; Shah, H.; TRIPATHI, C.

    2011-01-01

    Background : Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare immune-mediated severe cutaneous adverse reactions with incidence rate of 0.05 to 2 persons per million populations per year. Drugs are the most commonly implicated in 95% of cases. Aims : To audit the causative drugs, clinical outcome, and cost of management in SJS, TEN, and SJS-TEN overlap. Setting and Design: Tertiary care hospitals-based multicentric retrospective study (case series). Materials and M...

  18. Associations between several sites of cancer and ten types of exhaust and combustion products; Results from a case-referent study in Montreal

    Energy Technology Data Exchange (ETDEWEB)

    Siemiatycki, J.; Stewart, P.; Nadon, L.; Dewar, R.; Richardson, L. (Epidemiology and Preventive Medicine Research Center, Institute Armand-Frappier, Laval-des-Rapides, Quebec (Canada)); Gerin, M. (Univ. of Montreal, Quebec (Canada). Dept. of Occupational and Environmental Health)

    1988-01-01

    A population-based case-referent study provided information on the associations between several types of cancer and 10 types of exhaust and combustion products. All site-exposure combinations were investigated. An increased lung cancer risk, in particular squamous-cell cancers, due to exposure to gasoline and diesel exhausts was found. Among the associations that have not been subject to previous attention, the most promising leads for further investigation are the possible relations between gasoline and diesel exhaust and colorectal cancers, gasoline exhaust and kidney cancer, coal combustion products and pancreatic cancer (and possibly non-adenocarcinoma lung cancer), combustion products of heating oil and prostatic cancer, and natural-gas combustion products and bladder cancer.

  19. Glenoid hypoplasia: A case series of ten shoulders

    Scientific Electronic Library Online (English)

    P, Ryan; P, Jordaan; JP, du Plessis; B, Vrettos; S, Roche.

    2014-12-01

    Full Text Available The terms 'glenoid hypoplasia', 'glenoid dysplasia' and 'dentate glenoid' refer to an uncommon developmental abnormality of the lower glenoid and scapular neck. The presenting symptoms are variable depending on the age at presentation, and in many cases the diagnosis is made incidentally on X-ray. T [...] he exact incidence is unknown, but is estimated in cadaveric and MRI studies to be in the region of 14.3% to 35% depending on the ethnic population studied.12 Current orthopaedic literature consists of case reports and small case series, with some of the more recent papers focusing on the arthroplasty management and implications.3-5

  20. Lessons learnt from ten performance assessment studies

    International Nuclear Information System (INIS)

    The management of radioactive wastes and, in particular, the safety assessment of radioactive waste disposal systems are areas of high priority in the programme of the OECD Nuclear Energy Agency (NEA). In 1994, a Working Group was set up under the PAAG (Performance Assessment Advisory Group) on Integrated Performance Assessments of Deep Repositories (IPAG). The aim of the group is to provide a forum for informed discussion on performance assessment (PA), and to examine the overall status of PA and specific issues identified by the group and the PAAG. This document presents the report of a first phase of work completed in December 1996 and is expected to be of most interest to practitioners of repository PA and those with an interest in technical review of PA studies. (K.A.)

  1. A ten years follow-up of the results of surgery for Dupuytren's disease. A study of fifty-eight cases.

    Science.gov (United States)

    Norotte, G; Apoil, A; Travers, V

    1988-01-01

    Fifty-eight patients (52 males and 6 females) operated on for Dupuytren contracture were examined by the same author with a more than ten year follow-up. At time of surgery the average was 55 years old. 69 hands (169 fingers) rated 4.33 according to the simplified Tubiana's score were treated by the same operative procedure: Mac Indoe's incision, digital Z plasty (if needed), subtotal fasciectomy and physiotherapy beginning 8 days postoperatively. At long term, recurrence appears for 49 hands (71%) one every two in the two first postoperative years, one out of five after five years. 24 of them were graded stage I. The recurrence appeared 14 times associated with an extension of the disease and the earlier, the higher was the initial stage. Some factors seem to be of a bad prognosis regarding recurrence: age (93% of recurrence under 50 years old) Ledderhose or Lapeyronie (100%) other associated diseases (Alcoholism, diabetes mellitus, epilepsy) and severe preoperative stage. Subjective results are good: 45 patients are satisfied and only 3 underwent a second operation. PMID:3233038

  2. TESTING THE HYPOTHESIS OF MARKET EFFICIENCY THROUGH ARTIFICIAL NEURAL NETWORKS: A CASE STUDY WITH THE TEN MAJOR IBOVESPA SHARES IN THE FIRST QUARTER OF 2011

    Directory of Open Access Journals (Sweden)

    Luiz Henrique Herling

    2013-01-01

    Full Text Available Fuel market is facing political, economic, social and environmental problems that are fuzzing the future of fossil energy sources and in face of these facts, countries are looking for hybrid and electric vehicles as part of solution in transportation sector due to the fact of electric vehicles use few or no fossil fuel. The objective in this article was to identify options until 2020 to introduce electric vehicle in the urban traffic of São Paulo city and to develop this study the method of literature review in secondary sources was used to present electric vehicle technologies and to identify parameters that were assessed through morphological analysis technique. In morphological analysis, sets of values were defined by the author for these parameters, possible combinations were structured, clearly impractical deployment options before 2020 were discarded and some viable solutions were analyzed in details. These analyses concluded that there are viable options for actual days in São Paulo city, but important requirements regarding technology, politic, market, infrastructure and innovation in products and services still need to be addressed and it is the main reason of electric vehicle remain unnoticed by consumers as an viable option. The challenges are great and the actors who are willing to solve them will find a promising market to explore.

  3. Primary lymphoma of the central nervous system: a clinical-pathological and immunohistochemical study of ten autopsy cases Linfoma primário do sistema nervoso central: estudo clínico-patológico e imuno-histoquímico de dez casos de necropsia

    Directory of Open Access Journals (Sweden)

    Henrique Costa

    2006-12-01

    Full Text Available CONTEXT: Primary central nervous system lymphomas (PCNSL are a rare subgroup of lymphomas generally associated with HIV and EBV. OBJECTIVE: To study ten autopsy cases of PCNSL, to describe the neuropathological findings, to characterize the phenotype of the neoplastic cells, to detect EBV in the lesion and to compare the findings with the clinical and laboratory data of the patients. METHOD: The clinical, histological and immunohistochemical data of ten cases of PCNSL, eight cases from patients with AIDS, identified among 265 autopsies of these patients were analyzed. RESULTS: Seven patients were males and the mean age was 40.9 years. The most frequent symptomatology was focal neurologic deficit (70%. Six patients presented with only one lesion. Histologically, densely cellular and polymorphous neoplasms with angiocentrism were observed, in 90% of cases. An association with other diseases was observed in four cases. Most patients had diffuse large B cell non-Hodgkin’s lymphoma. EBV was detected by immunohistochemistry in only one case. The lack of detection of the virus might have been due to the long time of fixation of the brain which might have inactivate epitopes therefore compromising the testing. CONCLUSION: In the present series, PCNSL presented with focal symptoms, with unifocal or multifocal lesions, with a predominant B-cell CD20 positive phenotype, rarely associated with EBV.CONTEXTO: Linfoma primário do sistema nervoso central (LP-SNC é raro subgrupo de linfomas relacionado à AIDS, geralmente associado EBV. OBJETIVO: Identificar os achados clínico-patológicos dos pacientes com LP-SNC. MÉTODO: Foram analisados dados clínicos, histológicos e imuno-histoquímicos de dez necrópsias de LP-SNC, oito deles de pacientes com AIDS, identificados entre 265 autopsias destes. RESULTADOS: Sete pacientes foram masculinos e a idade média foi 40,9 anos. A sintomatologia neurológica mais freqüente era focal (70%. Seis exibiram lesão única. Histologicamente, eram neoplasias densamente celulares e polimorfas, com angiocentrismo em 90% dos casos. Em quatro casos, houve associação com outras afecções. A maioria dos casos foi de linfoma não-Hodgkin difuso de grandes células B. A pesquisa para EBV foi positiva em um caso. CONCLUSÃO: Predominaram os LP-SNC associados à AIDS, com sintomatologia focal, lesão em massa ou multifocal, com predominância de células B CD-20.

  4. Ten-Year Study of a Wilson's Disease Dysarthric.

    Science.gov (United States)

    Day, Linda Susan; Parnell, Martha M.

    1987-01-01

    The 10-year longitudinal case study describes the history, speech therapy program, and treatment results for an adult male with Wilson's disease, a genetically based metabolic progressive neurological disorder which includes severe speech problems. (DB)

  5. A theoretical study of ten N8 isomers

    OpenAIRE

    Gagliardi, Laura; Evangelisti, Stefano; Roos, Björn O.; Widmark, Per-O.

    1998-01-01

    The HF/3s2pld and MP2/3s2pld structures, energies and vibrational frequencies were calculated for ten N8 isomers, corresponding to ten analogous CH structures. Comparative calculations using density functional theory (DFT), with a cc-pVTZ basis set, were also performed. All ten structures were found to be local minima on the energy hypersurface at the Hartree-Fock (HF) level, whereas at the second-order Möller-Plesset (MP2) level nine structures were stable. At the DFT level, eight local mini...

  6. Case Studies

    International Nuclear Information System (INIS)

    Proven options available to Sri Lanka for large scale electricity generation in the future are coal-fired thermal, oil-fired thermal and Nuclear. Four case studies for groups participated are indicated. Case study for group 1 is comparison of the three options by taking into consideration the capital and recurrent expenditure involved. Environmental effects of the three options are also given. Case study for group 2 is economic comparison of three renewable energy based power generation system. Case study for group 3 is based on energy conservation, efficiency, improvement and demand management. Assuming that a continuous saving of 20 MW of demand from 1996 onwards is effective two projects are suggested to achieve this result. Case study for group 4 is a feasibility study for hydro power development of the Kukule Ganga (river) in Sri Lanka. Participants are required to evaluate one of the three optional development concepts which are technically feasible

  7. [Allergy to food colouring. A prospective study in ten children].

    Science.gov (United States)

    Zenaidi, Makram; Pauliat, Sylvie; Chaliier, Pierre; Fratta, Anne; Girardet, Jean Philippe

    2005-07-01

    In order to know more about allergy to food colouring, we conducted a prospective open study over 8 months in a group of 10 atopic children with repeated urticaria. The mean age was 6.5 years (4.2 - 13.5 years). The diagnosis was based on oral challenge tests along with hisory taking there were 3 cases of allergy to food colourings. Clinical features were mainly skin symptoms, sometimes associated with GI manifestations which were not only rare (1 case in our series) but also non specific. Colourings-free diet was recommended in consequence. It resulted in the disappearance of the symptoms in a child (Red cochineal) and their regression in the two others (Red cochineal, Red beet) with a follow up of 8 months and 3 months respectively. PMID:16220699

  8. How do governments become great? Ten cases, two competing explanations, one large research agenda

    OpenAIRE

    Andrews, Matt

    2013-01-01

    Governments can play great roles in their countries, regions, and cities; facilitating or leading the resolution of festering problems and opening new pathways for progress. Examples are more numerous than one might imagine and raise an important question: 'how do governments become great?'. This paper identifies ten cases of great governments to answer four dimensions of this question: What kinds of interventions or changes help governments achieve greatness? Who leads these interventions or...

  9. A retrospective study of the pattern of sexually transmitted diseases during a ten-year period

    Directory of Open Access Journals (Sweden)

    Narayanan Beena

    2005-01-01

    Full Text Available Background: Proper knowledge of the patterns of sexually transmitted diseases (STDs in different geographical regions is necessary for evolving proper strategies for control of these diseases. Aims: To study the pattern of STDs and to analyze the changes during a ten-year period from 1990 among patients attending Medical College Hospital, Kottayam Methods: Case records of 686 patients with STDs who attended the outpatient wing of the Department of Dermatology and Venereology were studied. Results: There were 504 males and 182 females in the total of 686 patients. Marital contact alone was reported by 123 (67.6% female patients. Genital ulcer diseases (GUDs accounted for the maximum number of STDs, with 504 cases (73.5%, followed by condyloma acuminatum (17.5% and gonorrhea (10.1%. Forty-three patients had multiple infections. The total number of patients during the first year of study was 129, while it was 41 during the last year. Bacterial STDs showed a striking reduction in numbers. The decline was less marked in the case of viral STDs. Conclusion: The majority of patients had genital ulcer diseases. Spouses were the most common source of infection for female patients. There was a marked decline in the number of patients with various STDs during the ten-year period. The decline was more evident in the bacterial STDs resulting in an apparent increase of the viral STDs towards the end of the period of study.

  10. A study of ten quasars with redshifts greater than four

    International Nuclear Information System (INIS)

    Four quasars with redshifts greater than four were detected in a low-resolution CCD grism survey. CCD photometry and high S/N, moderate resolution spectra are presented for these quasars and the six other known quasars with redshifts above 4. The M sub B values of nine of the objects are between -27.5 and -25, with the tenth quasar having an M sub B value of -29. The emission lines and shapes of the continua of these ten quasars are similar to those of lower-redshift quasars. The results suggest that the C IV emission lines in high-redshift quasars may be weaker than those in lower-redshift quasars. The continua of all of the high-redshift quasars display strong depressions blueward of the Ly-alpha emission line. 31 refs

  11. Neutron therapy of low grade 'pencil' gliomas of the spinal cord: A review of ten cases

    International Nuclear Information System (INIS)

    Between 1980 and 1986 ten patients (two males, eight females, median age: 35 years) with spongioblastomas and ependymomas grade I of the spinal cord were treated with fast neutrons from the d(14)+Be reaction after incomplete tumour surgery. Eight patients received three weekly fractions of 0.7 to 1.33 Gy and two patients four weekly fractions of 0.8 Gy to total doses of 7.4 to 10.4 Gy. Two complete and six partial remissions of ataxia and motor disturbances were observed. Bladder dysfunctions in five patients cleared up partially in three cases. In two patients the symptomatology remained unchanged. After a follow-up of eight to 88 months two initially complete and two out of six partial remission were maintained. No severe late effects of the skin have been determined. In summary it is concluded that for incompletely resected 'pencil'-gliomas fast neutrons therapy seems to be a feasible treatment modality. (orig.)

  12. Ten most notable family medicine research studies in Canada

    Science.gov (United States)

    Levitt, Cheryl; Katz, Alan; Mang, Eric; Safarov, Artem

    2015-01-01

    Abstract Objective To identify 10 noteworthy Canadian family medicine research studies that have affected practice in order to demonstrate the unique value that Canadian family medicine research offers. Composition of the committee Representatives from the Section of Researchers (SOR) and the Health Policy and Government Relations department of the College of Family Physicians of Canada developed a framework for inclusion and identified an initial list of articles. Members of the SOR Council and research directors from the 17 Canadian departments of family medicine reviewed the preliminary list and suggested additional studies. Methods The authors developed an initial list of studies carried out by Canadian family medicine researchers from those researchers who had received awards from the College of Family Physicians of Canada since 2002. Additional studies were proposed by members of the SOR Council and the university research directors. A total of 36 published articles were reviewed by the SOR authors, and an annotated short list of 16 articles was prepared. From that list, the other authors identified 7 noteworthy studies that were used to form the basis of advocacy materials. The SOR authors, along with 3 additional members of the SOR Executive, used an informal consensus process to select the final 3 articles to arrive at the top 10. Report The top 10 most noteworthy family medicine research studies are presented in this article and represent the unique contribution that Canadian family medicine research brings to health care in Canada. They have helped advance health care quality and improve care delivery, beneficially influencing health care practices, health care policy, and patient experiences. Conclusion This project has identified 10 classic Canadian family medicine research studies that continue to influence practice today. In addition to their usefulness as tools for teaching, advocating, and championing the contribution of research to modern family practice, these studies are important examples of the value of research to patient health in Canada and around the world.

  13. Computers in College Composition: A Comparative Study of Ten Schools.

    Science.gov (United States)

    Gardner, Ruth; McGinnis, Jo

    To compare information about the uses of computers in composition in representative universities, this document reports on a study that gathered data from teachers, administrators, and students at 10 universities by means of questionnaires and interviews by letter, by phone, and in person during visits to campus computer labs and classrooms. The…

  14. Temperament and character in eating disorders: ten years of studies.

    Science.gov (United States)

    Fassino, S; Amianto, F; Gramaglia, C; Facchini, F; Abbate Daga, G

    2004-06-01

    In recent years a number of studies of personality have been performed in subjects with Eating Disorders (EDs) to investigate the clinical differences between controls and ED patients and among EDs subtypes, and its role in the development and course of symptoms. The Tridimensional Personality Questionnaire (TPQ) and the Temperament and Character Inventory (TCI) have been widely used at this purpose, allowing the description of specific temperament and character profiles for EDs. High Harm Avoidance (HA) and low Self-Directedness (SD) are shared by all EDs. Slight differences on some facets have been found among ED subgroups. Nevertheless, HA is influenced by mood and both high HA and low SD are personality traits shared by many mental disorders, whose specificity is rather low. Restrictor anorectics are characterized by high Persistence (P) and a relatively higher SD, and bulimics by higher Novelty Seeking (NS) and the lowest SD, while binge/purging and purging anorectics share some traits with anorexia and some with bulimia. Though current data justify the discrimination among anorexia subtypes, they are not in contrast with the thesis of a continuum in ED personality traits. Since some personality traits display a prognostic value with regard to therapy and clinical outcome, further studies are needed on treatments and prognostic factors in EDs. Moreover, studies attempting to define the neurobiological and genetic correlates of temperament should be supported by clinical pharmacological trials. PMID:15330074

  15. Radiology and pathology of malignant fibrous histiocytomas of the soft tissues; a report of ten cases

    Energy Technology Data Exchange (ETDEWEB)

    Fischer, H.J.; Lois, J.F.; Gomes, A.S.; Mirra, J.M.; Deutsch, L.S.

    1985-03-01

    Malignant fibrous histiocytomas (MFH) are believed to originate from histiocytes and are composed of malignant cells with spindle or round shapes. We evaluated ten MFH of the soft tissues by plain roentgenograms, computed tomography (CT), and angiography and subdivided them into four grades of anaplasia and five predominant histologic variants. The variants of MFH demonstrated different vascular patterns. The extension of the lesions could be determinded by CT and angiography. CT is the method of choice in the assessment of size and extent of MFH of the soft tissues. When intra-arterial chemotherapy is indicated the angiograms obtained at each catheter placement may substitute CT in follow-up studies obviating additional diagnostic procedures.

  16. Radiology and pathology of malignant fibrous histiocytomas of the soft tissues a report of ten cases

    International Nuclear Information System (INIS)

    Malignant fibrous histiocytomas (MFH) are believed to originate from histiocytes and are composed of malignant cells with spindle or round shapes. We evaluated ten MFH of the soft tissues by plain roentgenograms, computed tomography (CT), and angiography and subdivided them into four grades of anaplasia and five predominant histologic variants. The variants of MFH demonstrated different vascular patterns. The extension of the lesions could be determinded by CT and angiography. CT is the method of choice in the assessment of size and extent of MFH of the soft tissues. When intra-arterial chemotherapy is indicated the angiograms obtained at each catheter placement may substitute CT in follow-up studies obviating additional diagnostic procedures. (orig.)

  17. Prognostic factors in children with acute lymphoblastic leukemia: a ten year study

    Directory of Open Access Journals (Sweden)

    Oloomi yazdi Z.

    2008-06-01

    Full Text Available Background: Acute lymphoblastic leukemia (ALL is the most common cancer in the pediatric population. With modern treatments, the chance of the complete recovery is nearly 100%. The most important prognostic factors are appropriate treatment protocol and determination of patient risk factors based on clinical, morphological, immunological and cytological characteristics. In this study we reviewed frequency of these factors, like as age, gender, the primary white blood cell number, sub- group on the base of FAB classification, immunophenotype and the clinical progress. Methods: In this retrospective study, we reviewed 877 pediatric patients with the diagnosis of ALL between the years of 1994 and 2004. In these patients the age, gender, primary WBC count, sub-group based on the FAB classification, immunophenotype and the clinical progress in 177 patient with acute lymphoblastic leukemia at Imam Khomeini Hospital between the years of 1994 to 2004 were determined. Results: Of these patients, 1.6% was younger than one year, 24.8% more than ten years old and 73.6% were between the ages of one and ten years; 63.8% were male. WBC counts were above 50,000/ul in 28.8% of the patients. FAB classifications included L1 in 80.2%, L2 in 17.5% and L3 in 2.3% of the patients. Immunophenotypes included pre-B cell in 63.8%, early pre-B cell in 23.1%, T cell in 12.3% and mature B cell in 0.8% of the patients. Marker CD10+ was detected in 88.1% of the B cell cases. In this study group, 74% of the patients recovered, 16.3% died and 16.5% relapsed.Conclusions: The prevalence of FAB-L1 and pre-B cell cases in this study is greater than a previous study, while the prevalence of FAB-L2 and early pre-B cell cases is less than that of the previous study.

  18. Perinatal Mortality And Pregnancy Wastage In Ten Punjab Villages During 1991-1996 - A Population Based Study

    OpenAIRE

    Sachar R K; Soni R.K; Singh W.P; Dhot Ramnik; Gill P.J.S; Arora Sona; Singh Hari; Dhiman B

    1998-01-01

    Research question: What is the extent of perinatal mortality and pregnancy wastage in rural Punjab and what are risk factors for the same. Objective: To quantify the perinatal; wastage and risk factors including the prevalence of these factors to determine the loss attributable to these factors in ten Punjab villages during the period 1991-1996. Study Design: Case control. Sample Size: 2519 pregnant women with Known outcome of pregnancy. Study Variables: Cause, timing and factors affecting pe...

  19. High Intensity Laser Therapy (HILT) versus TENS and NSAIDs in low back pain: clinical study

    Science.gov (United States)

    Zati, Allesandro; Fortuna, Damiano; Valent, A.; Filippi, M. V.; Bilotta, Teresa W.

    2004-09-01

    Low back pain, caused by lumbar disc herniation, is prevalently treated with a conservative approach. In this study we valued the efficacy of High Intensity Laser Therapy (HILT), compared with accepted therapies such as TENS and NSAIDs. Laser therapy obtained similar results in the short term, but better clinical effect over time than TENS and NSAIDs. In conclusion high intensity laser therapy appears to be a interesting new treatment, worthy of further research.

  20. [Treatment of Poland syndrome thorax deformity with the lipomodeling technique: about ten cases].

    Science.gov (United States)

    La Marca, S; Delay, E; Toussoun, G; Ho Quoc, C; Sinna, R

    2013-02-01

    The correct management, with the classic techniques, of the thoracic deformity in Poland's syndrome is difficult, with often insatisfactory results. The current surgical treatment involves the use of prothetic material and/or different flaps with their own complications and scares. The experience of our team with fat grafting (we named lipomodeling) in breast reconstruction helped us to propose the correction of the thoracic and mammary deformity by repeated fat transfer sessions. Fat grafting is commonly used in our team since 1998 in various indication of breast surgery. We reviewed retrospectively our ten first cases of thoracic deformity in Poland's syndrome treated with only fat grafting. Patients had repeated procedures until obtaining a satisfactory result. The fat was harvested from the thigh, buttocks, and abdomen. There were young patients with a mean age of 16years old (from 12 to 24). The mean follow-up was 51months. An average of 2.9 procedures (1 to 5) with 255cm(3) of fat injection at each procedure was needed to obtain symetry. Hundred percent of the patients were satisfied. No complication was noted. As reported, the reconstruction of the thoracic deformity and the mammary shape can be obtained by fat grafting. The absence of a flap donor site sequelae and the absence an implant allow this technique to be simple, reproductible, and without great complication. These criteria match well the surgical management of this deformity, which is mainly aesthetic. Moreover, the secondary benefit of liposuction of disgracious steatomery helps the acceptance of the procedure. Therefore in our hands, fat grafting to the breast (lipomodeling) is now our first choice treatment in thoracic Poland syndrome deformity. Given the rarity of this syndrome, we recommend a treatment by an operator who makes the learning curve of lipomodeling, and who often deals with Poland syndrome. PMID:23153632

  1. Ten cases of metastatic cervical cancer with the treatment of permanent 125I seeds interstitial implants

    International Nuclear Information System (INIS)

    Objective: To investigate the clinical effect of permanent 125I seeds interstitial implants for metastatic cervical cancer. Methods: Under the guidance of the B-sonography, 125I seeds were implanted into the eleven cervical lymph nodes of ten patients who had been given tumor resection. The pain relief and tumor size were observed in regular follow-up after one-month treatment. Results: All the patients were followed up for 6-14 months,and the postoperative recovery was good with no complication. One month after the implantation, the pain symptom was alleviated entirely in two nodes and partly in nine nodes. The tumor size shrank in ten nodes while there was no change in one node after one month. Conclusion: Permanent 125I seeds interstitial implants for metastatic cervical cancer is a safe, minimally invasive and effective treatment. (authors)

  2. "Contagious Love": A Qualitative Study of the Couple Relationships of Ten AIDS Carriers

    OpenAIRE

    Doron, Hadas; Teichner, Noa; Grey, Adi; Goldstein, Yehudit

    2008-01-01

    The qualitative study in this article portrays the couple relationship among AIDS carriers, based on Sternberg's triangular love theory (involving domains of intimacy, passion and commitment). The central study hypothesis is that certain components of the Sternberg model will be more significant than others among the AIDS carrier population. The study was conducted on ten AIDS carriers aged 21-37 who had experienced a couple relationship. Six men and four women participated; most of them were...

  3. Ten years of experience with pediatric neuroendoscopic third ventriculostomy: features and perioperative complications of 210 cases.

    Science.gov (United States)

    Baykan, Nigar; Isbir, Olcay; Gerçek, Arzu; Da?çnar, Adnan; Ozek, M Memet

    2005-01-01

    Obstructive hydrocephalus remains a problem, and improvements in fiberoptic technology have promoted interest in neuroendoscopic ventriculostomy (NTV) as an alternative to standard cerebrospinal fluid shunts. The present study assessed 210 pediatric NTVs performed between 1994 and 2004 in patients aged 2 months to 10 years. Five children needed same-session ventriculoperitoneal shunting due to insufficient bypass of the obstruction. The other 205 procedures were technically successful, but 7 patients needed early-postoperative shunting and 10 required late shunting. During NTV, 86 (40.1%) of the patients developed arrhythmia. One patient arrested during balloon dilatation, but normal rhythm returned after deflation and epinephrine/atropine therapy, with no resultant morbidity. Twenty-six (10.2%) patients developed tachycardia (without hypertension) followed by bradycardia, and 6 children (2.8%) developed hypertension. In 1 case (0.5%), a branch of the basilar artery ruptured during fenestration and the hemorrhage was controlled after craniotomy. In 5 cases, mild venous bleeding was controlled by irrigation. The early complications included transient ocular divergence (n = 1), anisocoria (n = 2), and hyponatremia (n = 5). Five children were diagnosed with temporary diabetes insipidus in the late-postoperative period. The neuroendoscopic approach is considered safe for treating hydrocephalus in children, but complications can be severe or lethal and the anesthesiologist must respond accordingly. PMID:15632540

  4. EFFECT OF CONVENTIONAL TENS VERSUS SPINAL MOBILIZATION IN PRIMARY DYSMENORRHEA IN ADOLESCENT GIRLS: A COMPARATIVE STUDY

    Directory of Open Access Journals (Sweden)

    Manisha Mistry

    2015-10-01

    Full Text Available Background: Primary dysmenorrhea is a common disabilitating factor in most of the adolescent girls. It is a major cause of inability to concentrate on their work or studies, class or school absenteeism, inability to perform in their academic activities. This study conducted to assess the effect of non-invasive treatments for pain relief during dysmenorrhea. Aim and Objectives: To study the effect of Conventional TENS and Spinal mobilization on pain in Primary Dysmenorrhea in adolescent girls. Materials and Methods: Fifty adolescent girls aged between 14-18 years were selected for the study that fulfilled the inclusion criteria. Quasi experimental study was done to compare the effect of TENS and Maitland’s spinal mobilisation in Adolscent girls suffering from primary dysmenorrhea. They were randomly divided in two groups: Group A for TENS (n= 24 and Group B for spinal mobilisation (n= 26 and participant’s menstrual history was recorded. Girls with severe dysmenorrhea, pelvic pathology and spinal pathology were excluded from this study. Treatment was given on 1st and 2nd day of menstruation period. Adolescent girls marked the Short form Mc gill Pain Questionnaire (SFMPQ which includes PPI and VAS before and just after the treatment. Total scores were noted and subjected to statistical analysis. Result: Data was analyzed using Mann Whitney U test which compared data between groups; results were not statistically significant (p> 0.05 for SFMPQ, PPI and VAS. Pain relief was approximately the same for the two groups. Conclusion: The study concludes that TENS and mobilisation both are effective reducing pain among adolescent girls who suffer from primary dysmenorrhea.

  5. Ten years of tuberculosis intervention in Greenland – has it prevented cases of childhood tuberculosis?

    Directory of Open Access Journals (Sweden)

    Emilie Birch

    2014-07-01

    Full Text Available Background: The incidence of tuberculosis (TB disease in Greenland doubled in the 1990s. To combat the increase, national TB interventions were initiated in 2000 and strengthened in 2007. Objective: To determine whether the effect of interventions could be detected, we estimated the TB disease risk among children?15 years before and after interventions were implemented. Design: For a study cohort, we recruited all children ?15 years of age included in the Greenlandic Civil Registration System (CRS from 1990 to 2010. The CRS identifier was used to link cohort participants with TB cases identified based on the Greenlandic National TB registry. Bacille Calmette Guerin (BCG vaccination status was identified through year of birth, as BCG was offered to newborns born either before 1991 or after 1996. Years with interventions were defined as 2000–2006 (primary interventions and 2007–2010 (intensified interventions. Risk of TB was estimated using Poisson regression. Results: The study included 35,858 children, of whom 209 had TB disease. The TB disease incidence decreased after interventions were implemented (2007–2010: IRR [incidence rate ratios] 0.62, 95% CI: 0.39–0.95, p=0.03, compared with the 1995–1999 period. The TB disease risk was inversely associated with BCG vaccination (IRR: 0.54, 95% CI: 0.41–0.72, p<0.001. Conclusions: Years with national TB interventions in Greenland, including neonate BCG vaccination, are associated with a lower TB disease incidence among children ?15 years of age.

  6. Ten years of tuberculosis intervention in Greenland - has it prevented cases of childhood tuberculosis?

    DEFF Research Database (Denmark)

    Birch, Emilie; Andersson, Mikael

    2014-01-01

    BACKGROUND: The incidence of tuberculosis (TB) disease in Greenland doubled in the 1990s. To combat the increase, national TB interventions were initiated in 2000 and strengthened in 2007. OBJECTIVE: To determine whether the effect of interventions could be detected, we estimated the TB disease risk among children?15 years before and after interventions were implemented. DESIGN: For a study cohort, we recruited all children ?15 years of age included in the Greenlandic Civil Registration System (CRS) from 1990 to 2010. The CRS identifier was used to link cohort participants with TB cases identified based on the Greenlandic National TB registry. Bacille Calmette Guerin (BCG) vaccination status was identified through year of birth, as BCG was offered to newborns born either before 1991 or after 1996. Years with interventions were defined as 2000-2006 (primary interventions) and 2007-2010 (intensified interventions). Risk of TB was estimated using Poisson regression. RESULTS: The study included 35,858 children, of whom 209 had TB disease. The TB disease incidence decreased after interventions were implemented (2007-2010: IRR [incidence rate ratios] 0.62, 95% CI: 0.39-0.95, p=0.03, compared with the 1995-1999 period). The TB disease risk was inversely associated with BCG vaccination (IRR: 0.54, 95% CI: 0.41-0.72, p<0.001). CONCLUSIONS: Years with national TB interventions in Greenland, including neonate BCG vaccination, are associated with a lower TB disease incidence among children ?15 years of age.

  7. [Axillary Lymph Nodes Metastases from Occult Breast Cancer Recurrence at Ten Years after Resection-Case Report].

    Science.gov (United States)

    Nagashima, Saki; Sakurai, Kenichi; Suzuki, Shuhei; Sakagami, Masashi; Adachi, Keita; Enomoto, Katsuhisa; Amano, Sadao

    2015-11-01

    We encountered a case of axillary lymph nodes metastases from occult breast cancer recurrence at 10 years after resection. Ten years previously, a 71-year-old woman had undergone surgery (dermabrasion+full thickness skin graft+axillary lymph node dissection) for axillary lymph nodes metastases from occult breast cancer. After the operation, she had received chemotherapy and hormone therapy for 5 years. Then, in the recent 5 years, she had stopped attending our hospital. Ten years after the first operation, she came back to our hospital with a lump in her axillary region. She underwent resection for the subcutaneous mass and the axillary lymph nodes. The pathological diagnosis implied metastases from breast carcinoma. We checked upa hole her body. However, we could not detect the original lesion. PMID:26805169

  8. ANALYSIS OF 138 CASES OF LUNG CANCER IN A TRAINING HOSPITAL COMPARED TO THE DATA OF LUNG CANCER CASES DIAGNOSED TEN YEARS PREVIOUSLY

    Directory of Open Access Journals (Sweden)

    Dilaver Taş

    2008-01-01

    Full Text Available Objective: To analyze data of cases with lung cancer (LC diagnosed in our clinic over one year period and compare them with data of cases with LC diagnosed before ten years. Method: The demographic data, radiological and bronchoscopic findings, diagnostic methods, and histological type and stages of the patients diagnosed with lung cancer in year 2005 were evaluated. Results: Over one year period, 138 patients were diagnosed with LC. 104 (75.4% were men and 34 (24.6% were women. Mean age was 63.78±9.53 (38-83. 118 (86.5% of the patients had 39±16.34 (5-90 pack-years smoking history. Squamous cell carcinoma (SCC was diagnosed in 40.6% of patients, adenocarcinoma in 29.0%, small cell carcinoma in 21.0%, conbined type in 8.0% and carcinoma with unidentified cell type in 1.4%. Squamous cell carcinoma was more common among smoking patients. It was determined that the distribution of histological types in this study was similar to the previous studies, however the incidence of LC was found as increased in females in our study when compared to previous studies. Conclusion: We conclude that SCC is the most common histological type in patients with LC in our clinic and the male to female ratio for LC is decreasing.

  9. Analyzing the Study of Using Acupuncture in Delivery in the Past Ten Years in China

    OpenAIRE

    Yingru Chen; Xuekai Zhang; Yigong Fang; Jinsheng Yang

    2014-01-01

    The use of acupuncture in inducing delivery has a long history in China. With progress over time, it has been applied in many aspects. For further study of acupuncture in delivery, this paper analyzed the papers using acupuncture in delivery in the past ten years in mainland China. 87 literatures were picked out by searching relevant electronic databases and bibliographies of relevant journals. The analysis showed randomized controlled trials that were the major type of research, while precli...

  10. Do Karst Rivers “deserve” their own biotic index? A ten years study on macrozoobenthos in Croatia

    OpenAIRE

    Ra?a Biljana; Puljas Sanja

    2010-01-01

    In this study we present the results of a ten year survey of the aquatic macroinvertebrate fauna along four karst rivers: Jadro, Žrnovnica, Grab and Ruda, all of them situated in the Middle Dalmatia region of Croatia, in an attempt to construct the Iliric Biotic Index, which will be more applicable for the water quality analysis than the most frequently applied biotic index in Croatia, the Italian Modification of Extended Biotic Index. The rivers geologically belong to the Dinaric karst, uniq...

  11. Case ten. Should two competing neighboring hospitals consolidate their emergency services?

    Science.gov (United States)

    Tibbetts, P L

    1990-01-01

    Two hospitals sit together on a medical campus located in a large metropolitan area. The larger (746 beds) of the hospitals, St. Catherine's, was established in 1887 by a Catholic congregation of religious women. The other hospital (527 beds), Martindale, was established by a group of Lutheran pastors in 1916. The missions of the two hospitals are very similar. The hospitals are strategically located in the center of a metropolitan area. The marketplace is one which has been characterized as fiercely competitive, with 40 percent of the market enrolled in prepaid plans. The demand for hospital services continues to decline each year. There is significant over capacity in the metropolitan area, with an average occupancy around 50 percent. The hospitals have had a varied history of both cooperation and competition. In 1975, a joint venture organization was established to jointly share expensive technology and develop new shared programs. After a brief study of the declining volumes and profitability in both hospital emergency rooms and identifying that both were perceived as substandard by the public and by the physicians, the question became--"should two competing, neighboring hospitals consolidate their emergency services?" The case reports a problem commonly experienced by hospitals today--when to compete, when to collaborate and how to balance the two in pursuit of organizational competence and advantage. PMID:10117090

  12. Hoarseness after Spinal Anaesthesia Persisting for Ten Days after Delivery: A Case Report

    OpenAIRE

    W-Q Sun; D-B Pan; A-G Zhou

    2015-01-01

    Hoarseness is common in general anaesthesia after tracheal intubation and brachial or cervial plexus block. However, there have been no reports of hoarseness associated with spinal anaesthesia in obstetric practice. We present a case of hoarseness in a parturient lasting for 10 days aftercombined spinal epidural anaesthesia with bupivacaine for Caesarean section. The hoarseness in this case may be caused by oedema of the vocal folds, which was due to high-level sympathetic blockade induced by...

  13. Hoarseness after Spinal Anaesthesia Persisting for Ten Days after Delivery: A Case Report

    Directory of Open Access Journals (Sweden)

    W-Q Sun

    2015-09-01

    Full Text Available Hoarseness is common in general anaesthesia after tracheal intubation and brachial or cervial plexus block. However, there have been no reports of hoarseness associated with spinal anaesthesia in obstetric practice. We present a case of hoarseness in a parturient lasting for 10 days aftercombined spinal epidural anaesthesia with bupivacaine for Caesarean section. The hoarseness in this case may be caused by oedema of the vocal folds, which was due to high-level sympathetic blockade induced by the spinal anaesthesia.

  14. Recurrent Tolosa-Hunt syndrome: a report of ten new cases.

    Science.gov (United States)

    Hannerz, J

    1999-12-01

    Ten patients (6F, 4M) with recurrent Tolosa-Hunt syndrome are reported. Besides ocular motor symptoms, one patient had trigeminal nerve involvement, one had ipsilateral ocular sympathicoplegia with miosis and ptosis, and one tinnitus during an episode of Tolosa-Hunt syndrome, ipsilateral to the pain side. One patient had Bell's palsy, one had a possible Raeder's syndrome, and one had a period of tinnitus between the Tolosa-Hunt syndrome episodes. Three of the 10 patients reported periods of periocular pain without ophthalmoplegia between the Tolosa-Hunt episodes, the pain located ipsilateral to the ophthalmoplegic side in the Tolosa-Hunt episodes. Systemic symptoms associated with Tolosa-Hunt syndrome, e.g., back pain, chronic fatigue, arthralgia, gut problems among others, occurred with the same frequency in these 10 patients as in an earlier report. Seventy per cent of the patients had signs of inflammation in serum during a period of Tolosa-Hunt syndrome. Orbital phlebograms showed pathologic signs in four of the five patients investigated during a Tolosa-Hunt period. One phlebogram was normal in a sixth patient when performed during a period of unilateral periocular pain without ophthalmolegia. Magnetic resonance imaging of the head (with contrast) was only performed in three patients during the Tolosa-Hunt period: one showed signs of inflammation in the middle fossa and two were normal. In one of the patients with normal magnetic resonance imaging, the orbital phlebogram was pathologic. Steroid treatment promptly relieved the pain in all patients. PMID:10668117

  15. Pharmacological Studies of Ten Medicinal Plants Used for Analgesic Purposes in Congo Brazzaville

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    Robin Janisson

    2011-01-01

    Full Text Available The aim of this study was to assess ten plants from the Congolese pharmacopoeia for their analgesic activity as well as their cytotoxicity, in order to validate their traditional use. Thirty-three extracts were obtained in 3 different solvents (Water, Ethanol, DCM from these ten plants selected after an ethnobotanic survey in the region of the Pool (Congo Brazzaville: Leonotis nepetaefolia (Lamiaceae, Manotes pruinosa (Connaraceae, Spilanthes uliginosa (Asteraceae, Hymenocardia ulmoides (Euphorbiaceae, Celosia trigyna (Amaranthaceae, Cogniauxia podolaena (Cucurbitaceae, Brillantaisia patula (Acanthaceae, Urena lobata (Malvaceae , Mitracarpus scaber (Rubiaceae, Triumfetta rhomboidea (Tiliaceae. The writhing test (Siegmund Chemical Test was used for the pharmacological screening. The cytotoxicity of all the extracts was tested on KB (Human epidermoid carcinoma and Vero (African green monkey kidney cell lines with taxotere as positive control. A TLC chemical screening of the extracts was carried out to detect the major chemical classes present in the plants. The data of the traditional medicine were confirmed, since eight plants out of ten were active, aqueous and ethanolic extracts being the most active. Moreover, only C. podolaena leaf extracts were cytotoxic (87% of inhibition on KB. This work opens the way for the research of the active molecules from these plants and for their use as leads in the synthesis and the pharmacomodulation of compounds with analgesic potentiality.

  16. In vitro antimicrobial activity of ten medicinal plants against clinical isolates of oral cancer cases

    Directory of Open Access Journals (Sweden)

    Kaushal Vivek

    2011-05-01

    Full Text Available Abstract Background Suppression of immune system in treated cancer patients may lead to secondary infections that obviate the need of antibiotics. In the present study, an attempt was made to understand the occurrence of secondary infections in immuno-suppressed patients along with herbal control of these infections with the following objectives to: (a isolate the microbial species from the treated oral cancer patients along with the estimation of absolute neutrophile counts of patients (b assess the in vitro antimicrobial activity medicinal plants against the above clinical isolates. Methods Blood and oral swab cultures were taken from 40 oral cancer patients undergoing treatment in the radiotherapy unit of Regional Cancer Institute, Pt. B.D.S. Health University, Rohtak, Haryana. Clinical isolates were identified by following general microbiological, staining and biochemical methods. The absolute neutrophile counts were done by following the standard methods. The medicinal plants selected for antimicrobial activity analysis were Asphodelus tenuifolius Cav., Asparagus racemosus Willd., Balanites aegyptiaca L., Cestrum diurnum L., Cordia dichotoma G. Forst, Eclipta alba L., Murraya koenigii (L. Spreng. , Pedalium murex L., Ricinus communis L. and Trigonella foenum graecum L. The antimicrobial efficacy of medicinal plants was evaluated by modified Kirby-Bauer disc diffusion method. MIC and MFC were investigated by serial two fold microbroth dilution method. Results Prevalent bacterial pathogens isolated were Staphylococcus aureus (23.2%, Escherichia coli (15.62%, Staphylococcus epidermidis (12.5%, Pseudomonas aeruginosa (9.37%, Klebsiella pneumonia (7.81%, Proteus mirabilis (3.6%, Proteus vulgaris (4.2% and the fungal pathogens were Candida albicans (14.6%, Aspergillus fumigatus (9.37%. Out of 40 cases, 35 (87.5% were observed as neutropenic. Eight medicinal plants (A. tenuifolius, A. racemosus, B. aegyptiaca, E. alba, M. koenigii, P. murex R. communis and T. foenum graecum showed significant antimicrobial activity (P P. aeruginosa was observed highest susceptible bacteria (46.6% on the basis of susceptible index. Conclusion It can be concluded that treated oral cancer patients were neutropenic and prone to secondary infection of microbes. The medicinal plant can prove as effective antimicrobial agent to check the secondary infections in treated cancer patients.

  17. Case Study Teaching

    Science.gov (United States)

    Herreid, Clyde Freeman

    2011-01-01

    This chapter describes the history of case study teaching, types of cases, and experimental data supporting their effectiveness. It also describes a model for comparing the efficacy of the various case study methods. (Contains 1 figure.)

  18. The clinical and imaging features of clear cell meningioma in ten cases

    Directory of Open Access Journals (Sweden)

    ZHAO Guang-zuo

    2012-10-01

    Full Text Available Objective To investigate the clinical features and imaging findings of intracranial clear cell meningioma. Methods The clinical data were reviewed, including presentation, imaging and prognosis of 10 patients suffered from intracranial clear cell meningioma for 2 months-7 years and underwent surgical treatment. The patients included five males and five females with the age from nine to sixty-two years old (mean 35.43. The tumors were located at cerebellopontine angle (CPA zone (n = 5, parietal lobe (n = 1, tuberculum sella (n = 1, jugular foramen (n = 1, tentorium of cerebellum (n = 1 or lateral cerebral ventricle (n = 1. The initial symptoms included headache (n = 4, gait disturbance (n = 2, hearing loss (n = 2, vision loss (n = 1 and bucking (n = 1 which were associated with the mass locations. Results CT (n = 8 and MRI (n = 10 of 10 patients were retrospectively reviewed. CT findings of the lesions presented with hyperdensity (n = 6, isodensity (n = 1, or isodensity with hyperdensity (n = 1. MRI T1WI showed isointensity (n = 4, hypointensity with isointensity (n = 4 or hyperintensity (n = 2, whereas T2WI isointensity with hyperintensity (n = 7, presented hypointensity (n = 1, isointensity (n = 1, or hyperintensity (n = 1. On gadolinium-enhanced T1WI, moderate enhancement was seen in 8 lesions and marked enhancement was seen in 2 lesions. In initial CT scanning peritumoral edema was found in 7 cases, dural tail sign in 5 cases, cysts in 7 cases, calcification in 3 cases, periosteal proliferation in 1 case and bone destruction in 5 cases. Seven patients underwent complete resection and 3 underwent subtotal resection. Follow-up period was 11-120 months. Recurrence occurred in 5 patients. The mean recurrence time was 55.62 months. Conclusion Clear cell meningioma is a rare meningioma and often occurs in young persons without significant difference in sex. The CPA zone is the most affected area. The prognosis is closely related to the extent of resection. Clear cell meningioma tends to present marked enhancement, peritumoral edema, cystic components, and bone involvement in imaging findings?

  19. Ten years of siting studies and public dialogue: the main lessons learnt at SKB

    International Nuclear Information System (INIS)

    It is more than 20 years since a co-ordinated nuclear waste management programme was set up in Sweden. Deep geological disposal of spent nuclear fuel in crystalline bedrock is the preferred option and an extensive R and D programme has been performed. A step-wise approach is being applied to development, technical demonstration and implementation of the disposal system. A key element of the programme is siting of the deep repository, which started in a focused manner almost ten years ago. Before that time a study-site drilling programme was performed 1977-85 and facilities for intermediate storage of the spent fuel (CLAB), final disposal of low and medium level waste (SFR) and underground research (Aespoe Hard Rock Laboratory) were sited during the 1980's [1, 2]. Thus, siting-related experiences to date within SKB encompasses: - Deep-drilling programme at about ten study-sites (1977-85). - Siting of CLAB, 1976-79. - Siting of SFR, 1980-83. - Siting of Aespoe HRL, 1986-90. - Feasibility studies on a voluntary basis in two municipalities in northern Sweden, Storuman and Mala, including local referenda 1995 and 1997. - Feasibility studies on a voluntary basis in six municipalities, Oesthammar, Nykoeping, Oskarshamn, Tierp, Hultsfred, Aelvkarleby, 1995-2001. By the end of this year SKB will present a comprehensive plan for the continuation of the siting programme at a few sites selected from the six municipalities where feasibility studies are now being finished. (author)

  20. Karyological studies in ten different populations of desert lily aloe vera from pakistan

    International Nuclear Information System (INIS)

    To enhance theoretical basis of Aloe feeding and provide cytological basement, the karyotype and morphology of mitotic chromosomes, ten different populations of Aloe vera collected from various geographical locations of Karachi, Pakistan were studied by aceto-orcein staining technique. The results showed that chromosome number of Aloe vera is 2n=14. The karyotype is bimodal and consists of 14 chromosomes (8 large and 6 small) predominantly with submedian, median and subterminal centromere. Average chromosome lengths among populations ranged from 7.95-2.36 micro m. (author)

  1. Intrascrotal lipoblastoma in a ten year old boy: case report and review of literature

    Directory of Open Access Journals (Sweden)

    Ghassan Nakib

    2013-02-01

    Full Text Available Lipoblastoma is a rare benign soft tissue tumor encountered almost exclusively in infancy and early childhood. The location of tumors varies, but most occur in the extremities, trunk, head and neck. Less frequently, lipoblastomas have been reported in the mediastinum, the retroperitoneum and the inguinal region. Only 7 cases of lipoblastoma in the scrotum have been reported so far in the English literature, with none of the patients older than 8. We report an intrascrotal lipoblastoma in a 10 year-old boy. The differential diagnosis is discussed with reference to the literature.

  2. Project management case studies

    CERN Document Server

    Kerzner, Harold R

    2013-01-01

    A new edition of the most popular book of project management case studies, expanded to include more than 100 cases plus a ""super case"" on the Iridium Project Case studies are an important part of project management education and training. This Fourth Edition of Harold Kerzner''s Project Management Case Studies features a number of new cases covering value measurement in project management. Also included is the well-received ""super case,"" which covers all aspects of project management and may be used as a capstone for a course. This new edition:Contains 100-plus case studies drawn from re

  3. Medical School Attrition-Beyond the Statistics A Ten Year Retrospective Study

    Directory of Open Access Journals (Sweden)

    Maher Bridget M

    2013-01-01

    Full Text Available Abstract Background Medical school attrition is important - securing a place in medical school is difficult and a high attrition rate can affect the academic reputation of a medical school and staff morale. More important, however, are the personal consequences of dropout for the student. The aims of our study were to examine factors associated with attrition over a ten-year period (2001–2011 and to study the personal effects of dropout on individual students. Methods The study included quantitative analysis of completed cohorts and qualitative analysis of ten-year data. Data were collected from individual student files, examination and admission records, exit interviews and staff interviews. Statistical analysis was carried out on five successive completed cohorts. Qualitative data from student files was transcribed and independently analysed by three authors. Data was coded and categorized and key themes were identified. Results Overall attrition rate was 5.7% (45/779 in 6 completed cohorts when students who transferred to other medical courses were excluded. Students from Kuwait and United Arab Emirates had the highest dropout rate (RR?=?5.70, 95% Confidence Intervals 2.65 to 12.27;p? Absenteeism was documented in 30% of students, academic difficulty in 55.7%, social isolation in 20%, and psychological morbidity in 40% (higher than other studies. Qualitative analysis revealed recurrent themes of isolation, failure, and despair. Student Welfare services were only accessed by one-third of dropout students. Conclusions While dropout is often multifactorial, certain red flag signals may alert us to risk of dropout including non-EU origin, academic struggling, absenteeism, social isolation, depression and leave of absence. Psychological morbidity amongst dropout students is high and Student Welfare services should be actively promoted. Absenteeism should prompt early intervention. Behind every dropout statistic lies a personal story. All medical schools have a duty of care to support students who leave the medical programme.

  4. Carbon Monoxide Poisoning: from the Perspective of Ten Years and 2417 Cases

    Directory of Open Access Journals (Sweden)

    Nurettin Özgür Do?an

    2012-09-01

    Full Text Available Objective: Carbon monoxide (CO poisoning is a common problem in various countries, especially in Winter months. CO exposure results in the formation of carboxyhemoglobin (COHb, which is responsible for toxicity symptoms. In this study, we aim to demonstrate the demographic features and seasonal variations of this particular public health problem. Materials and Methods: We retrospectively evaluated hospital police reports and medical records of 2417 ED patients diagnosed with CO poisoning between 1999 and 2009. Sources of exposure, seasonal variation and demographic characteristics were analyzed. Results: The mean age of the patients, of whom 1418 (58.7% were female, was 29±18 years. While 1708 patients (70.7% were admitted to adult ED, 709 (29.3% patients were admitted to pediatric ED. January and subsequent Winter months represented the most dangerous periods for CO exposure. No intentional (suicidal attempt exposure to CO intoxication was reported and the major cause for intoxication included unsecured stoves and gas heaters. Conclusion: Emergency physicians should be familiar with symptoms and remedies of CO intoxication, which still constitutes a serious health problem.

  5. Case Management insider. The top ten mistakes you may be making in your case management department!: Part 1.

    Science.gov (United States)

    Cesta, Toni

    2015-06-01

    This month we have begun reviewing the top mistakes hospitals make within their case management department's infrastructure. As discussed, the biggest mistake is to not clearly and prospectively define the roles of the RN case manager and the social worker to optimize each discipline's skill sets. Associated with this mistake is to have inadequate patient ratios assigned to each discipline. These mistakes are related and when roles are not clearly defined, it becomes almost impossible to understand or advocate for appropriate staffing ratios. If it appears that nurses and social workers can all do the same things equally well, then the organization will likely choose to go with the professional group that will cost the organization the least amount of money. In the end, this logic is penny-wise and pound foolish. We do both disciplines a disservice when we don't apply their skill sets adequately and don't have each group functioning at the "top of their license!" Next month, we will continue to discuss the top mistakes hospitals make in their acute care management departments' design. We will discuss the use of clerical support staff, assessments, and days of coverage. PMID:26031112

  6. A ten-year study of depressive symptoms in Serbian medical students.

    Science.gov (United States)

    Risti?-Ignjatovi?, Dragana; Hini?, Darko; Jakovljevi?, Mihajlo; Fountoulakis, Kostas; Siepera, Marianna; Ranci?, Nemanja

    2013-06-01

    The main objective of this study was to examine the rate of three dimensions of depressive symptoms in medical student population in Serbia, and to find out whether this rate had changed over the period often years. This cross-sectional study included 615 medical students (F = 61% and M = 39%), mean age = 23.60 (SD = 1.541), who were tested in five non-consecutive surveys between 2002 and 2012. Depressive symptoms were measured by the Beck Depression Inventory (BDI). The mean BDI score for the entire sample was 6.26 +/- 6.175. There was no significant difference in total BDI score among the values obtained during the ten years of testing. The greatest portion of the examined sample (77.24%) had no signs of depressive symptoms, and there was no difference in symptom intensity between medical students and other educational profiles. Similar to previous results, females had higher scores on all depressive dimensions except for one tested year, whereas a weak correlation was found between BDI scores and student age (r = 0.104; p = 0.010). Since there are still discrepancies among studies that do (not) report that medical students have typical depressive symptoms, potential explanations for the mentioned discrepancies may be found in individual characteristics of the members of the student population. Our suggestions for future studies are that they should include the stress factor, stress coping strategies, estimated life satisfaction, and the impact of these factors on the potential mental disorders. PMID:24053075

  7. Stakeholders’ Views on Factors Influencing Nutrition Policy: a Qualitative Study Across Ten European Countries

    Directory of Open Access Journals (Sweden)

    Jeruszka-Bielak Marta

    2015-12-01

    Full Text Available The objective was to identify the main factors influencing micronutrient policies in the opinion of policy actors in ten European countries. Study was carried out during Jan-Nov 2010 in European countries: the Czech Republic, Denmark, England, Germany, Greece, Italy, the Netherlands, Norway, Poland and Spain. Semi-structured qualitative interviews were conducted with representatives of stakeholders involved in the vitamin D, folate and iodine policy making process. Fifty eight key informants representing mainly scientific advisory bodies (n=24 and governmental organisations (n=19 participated in the study. The remaining interviewees represented non-governmental organisations (n=6, industry (n=4 or were independent academic or health professional experts (n=5. Data were analysed by theoretical interpretative thematic analysis. Insights from interviewees on the development of micronutrient policies were grouped using the Public Health Nutrition Policy-making model. The main factors influencing the micronutrient policies were: systematic monitoring of nutrition and health, causal relationships between consumers’ diet-related behaviours and health outcomes, scientific recommendations from national bodies (Science area; scientific recommendations from international authorities and experiences of other countries, EU legislation, cultural factors (Wider context and political environment, national capacity to deal with the problem, national legislation, economics, stakeholder engagement, relationships between stakeholders (Policy and institutions area. The spectrum and weight of the factors influencing nutritional policy depends on nutrient, country and degree of its “advanced status” within nutrition policy, political environment, culture and socio-economic conditions as well as the point of view (who is expressing the opinion.

  8. A Ten Year Descriptive Study of Adult Leukaemia at Al-Jomhori Teaching Hospital in Sana'a, Yemen

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    Jameel Al-Ghazaly

    2014-12-01

    Full Text Available Background: There is scarcity of data of the epidemiology of leukaemia in Arab countries including Yemen. Understanding patterns of leukaemia underpins epidemiology and can provide insight into disease etiology. The aim of this research is to determine the epidemiologic pattern of adult leukaemia in Yemen. Methods: The research is a descriptive cross-sectional study. We analyzed the data of 702 adult patients with leukaemia, who were newly diagnosed over a ten-year period between October 1999 and October 2009 at the referral haematology centre in Sana’a at Al-Jomhori Teaching Hospital, according to type of leukaemia, age, sex, geographic distribution and time of diagnosis. Results: Acute Myeloid Leukaemia (AML was found to be the most common (45.1% followed by Chronic Myeloid Leukaemia (CML (26.5%, Acute Lymphoid Leukaemia (ALL (17.7% and Chronic Lymphoid Leukaemia (CLL (10.7%, respectively. There was an almost equal prevalence of AML and CML for males and females but males had significantly more cases of ALL and CLL (p =0.008. A significant variation in geographic pattern showed that the highest number of cases is seen the Central mountainous region and the least number of cases in the South-eastern region which is coastal and lowland (p<0.001. The seasonal variation showed that higher number of ALL cases was seen in the summer months (33% compared with other seasons (21% in the spring, 24.2% in autumn and 21.8% in winter. Conclusions: The pattern of adult leukaemia in Yemen is different from that seen in western countries which could be attributed to different environmental exposure. The geographic pattern indicates a possible role of certain environmental factors which warrant further investigations. The pattern of seasonal variation needs further studies for evaluating the seasonality.

  9. Tumor del cuerpo carotídeo: A propósito de 10 casos tratados / Carotid body tumors: Report of ten cases

    Scientific Electronic Library Online (English)

    Sebastián, Soto G; Francisco, Valdés E; Albrecht, Krámer Sen; Leopoldo, Mariné M; Michel, Bergoeing R; Renato, Mertens M; Antonieta, Solar G; Annerleim, Walton D; Jeannette, Vergara G.

    2007-11-01

    Full Text Available [...] Abstract in english Background: Carotid body tumors arise from a cellular conglomerate located at the carotid bifurcation. Progressive enlargement can involve the arterial wall and neighbor cranial nerves. Aim: To report a series of 10 patients treated of carotid body tumors and review national experience. Patients and [...] methods: Between 1984 and 2006, we operated 8 women and 2 men, aged 19 to 75 years, with this type of tumor. Results: The most common cause for consultation was a cervical mass in 90%, with a mean evolution lapse of 13.2 months (range 3 to 126). In all cases, diagnosis was confirmed with angiographic imaging and histopathology. Ten tumors were surgically removed with no complications. Eighty percent of tumors were in stage II according to Shamblin classification. During long term follow up all patients have remained asymptomatic. Only 31 carotid body tumors have been reported in Chilean medical literature during a 43 year period. Conclusions: Paragangliomas of the carotid body can be diagnosed in clinical grounds, requiring vascular imaging. These infrequent lesions are generally benign, early surgical removal by surgeons with vascular expertise avoids neurological and or vascular complications

  10. Tumors of the liver; a ten year study in Children Medical Center

    Directory of Open Access Journals (Sweden)

    Farahmand F

    2007-06-01

    Full Text Available Background: The aim of this study was to review the frequency, histopathology and outcome in children with tumors of the liver. Methods: Included in this retrospective/descriptive study were 30 children treated for liver tumors from 1375-1384 (ca. 1996-2005, at Children’s Hospital Medical Center, Tehran, Iran. We included the clinical, radiologic, and pathologic data of our patients, focusing on the frequency, etiology and outcome. Results: Patient ages ranged from three months to 12 years (median 3.8 years, with 18 males (60% and 12 females (40%. Of these, 17 patients had hepatoblastoma (55.66%, including 13 males and four females, with an age range of six months to five years. Four cases (13.33% had neuroblastoma. Hepatocellular carcinoma (HCC was found in three cases (10%, all of whom were carriers of hepatitis B. Two cases (6.66% were diagnosed with mesenchymal hamartoma, two cases (6.66% with hemangioendothelioma and two cases (6.66% with rhabdomyosarcoma and leiomyosarcoma of the biliary tract. Abdominal swelling and hepatomegaly were seen in all of patients. Jaundice was observed in two cases. Serum alpha-fetoprotein levels greater than 500 ng/ml were seen in 17 cases (56.66%. All patients were receiving specific treatment. The three-year survival rate was 65% for hepatoblastoma and 2% for HCC Conclusion: With the introduction of specific treatment, the survival rate for children with tumors of the liver has significantly increased. Further improvement can be achieved using diagnostic biopsy for hepatoblastoma, although it may result in complications, and preoperative chemotherapy followed by complete surgical excision (per International Society of Pediatric Oncology guidelines, yielding an outstanding survival rate of 80%.

  11. Do Karst Rivers “deserve” their own biotic index? A ten years study on macrozoobenthos in Croatia

    Directory of Open Access Journals (Sweden)

    Ra?a Biljana

    2010-07-01

    Full Text Available In this study we present the results of a ten year survey of the aquatic macroinvertebrate fauna along four karst rivers: Jadro, Žrnovnica, Grab and Ruda, all of them situated in the Middle Dalmatia region of Croatia, in an attempt to construct the Iliric Biotic Index, which will be more applicable for the water quality analysis than the most frequently applied biotic index in Croatia, the Italian Modification of Extended Biotic Index. The rivers geologically belong to the Dinaric karst, unique geological phenomena in Europe. Benthic macroinvertebrates were collected along each river at 15 sites by standard methods of sampling along with several physicochemical parameters, including: temperature, dissolved oxygen, carbon dioxide, alkalinity, hardness and pH. Univariate and multivariate techniques revealed differences in the macroinvertebrate community structure as well as in physicochemical parameters between the Karst rivers and continental rivers. Based on those differences, the Iliric Biotic Index was proposed as the standard of karst river water quality in Croatia in accordance with the EU Water Framework Directive. Differences between the Iliric Biotic Index and the most commonly used biotic indices in the European Community and the USA (The Biological Monitoring Working Party (B.M.W.P. scores, i.e. Extended Biotic Index, Indice Biotique, Family Biotic Index suggest that karst rivers need a new biotic index.

  12. The study of multi-frequency scattering of ten radio pulsars

    CERN Document Server

    Lewandowski, Wojciech; Kijak, Jaroslaw; Bhattacharyya, Bhaswati; Roy, Jayanta

    2015-01-01

    We present the results of the multi-frequency scatter time measurements for ten radio pulsars that were relatively less studied in this regard. The observations were performed using the Giant Meterwave Radio Telescope at the observing frequencies of 150, 235, 325, 610 and 1060~MHz. The data we collected, in conjunction with the results from other frequencies published earlier, allowed us to estimate the scatter time frequency scaling indices for eight of these sources. For PSR J1852$-$0635 it occurred that its profile undergoes a strong evolution with frequency, which makes the scatter time measurements difficult to perform, and for PSR J1835$-$1020 we were able to obtain reliable pulse broadening estimates at only two frequencies. We used the eight frequency scaling indices to estimate both: the electron density fluctuation strengths along the respective lines-of-sight, and the standardized amount of scattering at the frequency of 1 GHz. Combining the new data with the results published earlier by Lewandowsk...

  13. Granuloma central de células gigantes: presentación de diez casos / Central giant cell granuloma: presentation of ten cases

    Scientific Electronic Library Online (English)

    Francisco Levi, Duque Serna; Lina María, Franco; Carlos Martín, Ardila Medina.

    2012-10-01

    Full Text Available Fundamento: el granuloma central de células gigantes (GCCG) es una lesión que ocupa el 7 % de los tumores benignos que se encuentra exclusivamente en los maxilares. Se presenta con más frecuencia en mujeres que en hombres y predomina en la segunda y tercera década de la vida. Las características rad [...] iográficas del GCCG son variables y pueden ser confundidas con otras lesiones de los maxilares. El GCCG puede tener un comportamiento agresivo lo que permite establecer el tratamiento de elección, incluyendo la enucleación, el curetaje y la resección en bloque de la lesión. Caso clínico: se presentaron diez casos de pacientes diagnosticados con GCCG. El 80 % de los casos se localizaron en la mandíbula con las siguientes características clínicas: asimetría facial, desplazamiento dental, reabsorción radicular, alteración de la oclusión y trastorno nervioso. Conclusiones: en cuatro sujetos se realizó resección en bloque con placa de reconstrucción, mientras que en los otros seis pacientes se llevó a cabo enucleación y curetaje. En el 100 % de los casos se efectuó un abordaje intraoral y no se presentaron complicaciones graves. El seguimiento clínico y radiográfico evidenció recidiva en uno de los pacientes, razón por la cual se precedió a realizar resección en bloque con placa de reconstrucción. Abstract in english Background: central giant cell granuloma (CGCG) is a lesion that occupies 7 % of benign tumors found exclusively in the jaws. It occurs more frequently in women than in men and predominates in the second and third decades of life. Radiographic features of CGCG are changeable, and may be confused wit [...] h other jaws' lesions. The CGCG may have aggressive behavior which allows setting the treatment of choice, including enucleation, curettage and resection of the lesion. Clinical case: ten cases of patients diagnosed with CGCG were presented. The 80 % of the cases were located in the jaw with the following clinical features: facial asymmetry, dental displacement, root resorption, altered occlusion and nerve disorder. Conclusions: in four patients resection in block was performed with reconstruction plate, while in six other patients enucleation and curettage was carried out. In the 100 % of the cases an intraoral approach was made without severe complications. There was clinical and radiographic evidence of recidivation in one of the patients, a resection with reconstruction plate was made.

  14. Case study evaluation.

    OpenAIRE

    KEEN, J.; Packwood, T

    1995-01-01

    Case study evaluations, using one or more qualitative methods, have been used to investigate important practical and policy questions in health care. This paper describes the features of a well designed case study and gives examples showing how qualitative methods are used in evaluations of health services and health policy.

  15. Is Electroconvulsive Therapy Fading into Oblivion? - A Study of Ten Year Trends

    Directory of Open Access Journals (Sweden)

    Aruna G

    2013-04-01

    Full Text Available Background: Despite proven efficacy, modified ECT has been variably used in the recent past, with data on the usage trend being scarce, worldwide. Aim: We aimed to do a time – series analysis to examine annual trends in modified ECT use in our tertiary teaching hospital in the last decade. Methods: A chart review was carried out on all patients who received m-ECT in our teaching hospital in the last ten years (2002 to 2011, and percentage of total inpatients receiving M-ECT each year was deduced. Along with number of ECT sessions given per year, details of demographic data, and indications for ECT were recorded. Results: In our study ECT was undersized as a treatment option, with only 1:13% of total inpatients having received ECT. Also it was noted that use began increasing from 2002, reaching a peak in 2006 (84% increase followed by a downward trend, with a sharp decline since 2008 (61%decrease and finally reaching a nadir in 2011 (69% decrease. Mean age of patients ranged from 31.28 to 40.1 years with a slightly high female preponderance in most year groups. The most common indication for ECT use was schizophrenia (47.8% followed by, depression (38.9%. Conclusion: Although, our study finding is in line with the downward trend of ECT utilization rates reported worldwide, the nature and magnitude of decline cannot be explained nor compared globally due to variations, inaccuracies and heterogeneity of ECT data currently available. Further, factors responsible for such trends should become focus of future research.

  16. Perinatal Mortality And Pregnancy Wastage In Ten Punjab Villages During 1991-1996 - A Population Based Study

    Directory of Open Access Journals (Sweden)

    Sachar R.K

    1998-01-01

    Full Text Available Research question: What is the extent of perinatal mortality and pregnancy wastage in rural Punjab and what are risk factors for the same. Objective: To quantify the perinatal; wastage and risk factors including the prevalence of these factors to determine the loss attributable to these factors in ten Punjab villages during the period 1991-1996. Study Design: Case control. Sample Size: 2519 pregnant women with Known outcome of pregnancy. Study Variables: Cause, timing and factors affecting perinatal mortality and pregnancy wastage (viz Wt.<40kg; Ht, <152cm,BMI, <20 illiteracy, birth to conception interval <100wks, Prematurity (Gestation <37 wks. Registered in IIIrd trimester, Registered in IInd Trimester, Home delivery. Outcome variables: Contribution of these factors in perinatal loss and pregnancy wastage. Analysis; Percentages, Odds ratio, confidence interval and population attributable risk%. Results: The perinatal mortality rate was 34.57/1000 and pregnancy wastage was 7.23%. Prematurity was the leading cause of perinatal loss. 31.25% of perinatal deaths took place within 24 hours and 87.5% within 96 hours. In case of perinatal mortality the odds ration were significant (p<0.05 for the following risk factors: weight, height, body mass index, illiteracy, birth to conception interval <1000 weeks, prematurity, registration of pregnancy in IInd trimester, registration of pregnancy in IIIrd trimester, home delivery. In case of pregnancy wastage the odds ratio were significant for the following risk factors: weight, height, body mass index, illiteracy, birth to conception interval <100weeks, prematurity, past history of abortion and low socio-economic status.

  17. Study on dosimetry systems for a few tens MeV/u ion beams

    Energy Technology Data Exchange (ETDEWEB)

    Kojima, Takuji; Sunaga, Hiromi; Takizawa, Haruki; Tachibana, Hiroyuki [Japan Atomic Energy Research Inst., Takasaki, Gunma (Japan). Takasaki Radiation Chemistry Research Establishment

    1997-03-01

    A combined measurement system consisting of a total calorimeter, a Faraday cup and thin film dosimeters have been developed and tested using a simultaneous irradiation apparatus to measure absorbed dose for a few tens MeV/u ion beams of the TIARA AVF cyclotron. (author)

  18. Hepatic resection for non-colorectal and non-neuroendocrine metastatic cancer: indications and results in ten resectable cases

    Directory of Open Access Journals (Sweden)

    Sergio Renato Pais Costa

    2008-03-01

    Full Text Available Objective: To report the early postoperative results and long-termsurvival on ten patients undergoing hepatectomy for treatmentof non-colorectal and non-neuroendocrine hepatic metastases.The study was carried out by the General Surgery Service of theDepartment of Digestive Tract Surgery of the Teaching Hospital ofthe Faculdade de Medicina do ABC, Santo André, São Paulo, Brazil.Methods: Complete follow-up data were available on 28 patientswith hepatic metastases who were operated on between January2002 and January 2007. Ten patients presented non-colorectal andnon-neuroendocrine primary neoplasms, and comprised the sampleof this study. There were five males and five females, mean age of53 years (28 to 68 years. The right lobe was involved in five patientsand the left lobe in five individuals. The number of metastasesranged from one to four. All metastases were unilateral. All primarytumors were identified. The histological types were adenocarcinoma(n = 7, germinative tumor (n = 1, melanoma (n = 1 and sarcoma(n = 1. The primary sites were: gastric (n = 1, kidney (n = 1,adrenal (n = 1, breast (n = 2, testicle (n = 1, ovary (n = 2,acral melanoma (n = 1 and retroperitoneal sarcoma (n = 1. Allpatients presented metachronous metastases. The median intervalbetween primary tumor treatment and diagnosis of metastases was20 months (12 to 33 months. Six patients received chemotherapyand four patients underwent exclusively surgical treatment. Results:There were seven major hepatic resections (three or more Couinaudsegments and three minor hepatic resections. The operative timevaried from 180 to 425 minutes with a median duration of 240minutes. Five patients received transfusions; blood loss ranged from200 to 3,000 ml. There were two postoperative complications andboth patients were re-operated (biliary fistula = 1; intra-abdominalabscess = 1. There were no postoperative deaths. All resectionswere R0. The three-year overall survival rate was 50%. Five patientsdeveloped tumor recurrence (50%. Conclusions: Hepatic resectionfor liver metastases other than of colorectal or neuroendocrine originpresents acceptable morbidity and no mortality. This approach mayresult in long-term survival in this group of patients.

  19. Tetanus in a Rural Setting of South-Western Nigeria: A Ten-Year Retrospective Study

    Directory of Open Access Journals (Sweden)

    O Adekanle

    2009-01-01

    Full Text Available We review the records of 79 tetanus patients in two hospitals (one tertiary and one secondary level inOwo, Ondo state, Nigeria from 1997 to 2006. The male: female ratio was 3:1. Ages were 14-70 years(mean 33.25 years, SD ±16.76. The overall case fatality rate (CFR, 32.91%, did was not significantlydifferent in the two hospitals. CFR for men was 32.10% and for women 35.29%. The main factorindicative of bad prognosis was a short hospitalization period. It was observed that 30.38% of ourpatients were discharged against medical advice (DAMA, that financial constraint was the underlyingproblem in 50% of cases, and that the trend of DAMA occurred at the two study sites. This DAMAphenomenon could pose a great danger to the eradication of this vaccine preventable disease in ruralareas.

  20. Consequences from use of reminiscence - a randomised intervention study in ten Danish nursing homes

    Directory of Open Access Journals (Sweden)

    Sørensen Jan

    2010-06-01

    Full Text Available Abstract Background Reminiscence is the systematic use of memories and recollections to strengthen self-identity and self-worth. The study aim was to investigate the consequences for nursing home residents and staff of integrating reminiscence into daily nursing care. Methods In this randomised study, ten nursing homes were matched into two groups on the basis of location, type and size. In the period August 2006 - August 2007, staff in the Intervention Group were trained and supported in the use of reminiscence, involving individual and group sessions with residents as well as reminiscence boxes, posters and exhibitions. At baseline and again 6 and 12 months after the intervention start, data were collected on residents' cognitive level, agitated behaviour, general functioning and proxy-assessed quality of life, as well as on staff well-being and job satisfaction. Mixed linear modelling was used to analyse differences in outcome between the intervention and control groups. Results Project drop-out rates were 32% for residents and 38% for nursing staff. Most staff in the Intervention Group considered reminiscence a useful tool that improved their communication with residents, and that they would recommend to other nursing homes. There were no significant differences between residents in the Intervention and the Control Group in cognitive level, agitated behaviour or general functioning. Residents in the Intervention Group showed significant higher score at 6 months in quality of life subscale 'Response to surroundings', but there was no significant difference at 12 months. Positive effects of reminiscence were observed for all staff outcome measures, the only exception being SF-12 self-rated physical health. At 6 months after start of reminiscence, staff in the Intervention Group had significantly better scores than those in the Control Group for Personal accomplishment, Emotional exhaustion, Depersonalisation, 'Attitude towards individual contact with residents' and SF-12 self-rated mental health. At 12 months after start of reminiscence, staff in the Intervention Group had significantly better scores than those in the Control Group for Emotional exhaustion and 'Professional role and development'. Conclusions The use of reminiscence appeared to have little long-term effect on the nursing home residents. Nursing staff in the Intervention Group experienced greater satisfaction with professional roles and developed a more positive view of the residents. International Standard Randomised Controlled Trial Number Register: ISRCTN90253170.

  1. Laos case study

    OpenAIRE

    Tenni Brigitte; Sychareun Vanphanom

    2012-01-01

    Abstract Peuan Mit is a Lao organization working to address the needs of children and youth living and working on the streets. This case study outlines how a trusted and strong relationship with local police provides mutual benefit.

  2. HYDROGEOLOGIC CASE STUDIES

    Science.gov (United States)

    Hydrogeology is the foundation of subsurface site characterization for evaluations of monitored natural attenuation (MNA). Three case studies are presented. Examples of the potentially detrimental effects of drilling additives on ground-water samples from monitoring wells are d...

  3. Ten-year study on varieties of parotid tumors in pediatrics

    International Nuclear Information System (INIS)

    Parotid tumors are uncommon because they account for 0.5 % of all types of cancer in pediatrics. They generally occur as increased local asymptomatic volume, occasionally accompanied by pain and inflammatory signs. A retrospective, longitudinal and descriptive study was carried out to determine the frequency and forms of presentation of parotid tumors diagnosed in 0-18 years-old patients, who had been admitted to the oncological surgery service of 'William Soler' pediatric hospital from February 2001 to December 2010. The variables taken into account were sex, forms of presentation, response to treatment as well as the histological variants presented, with the objective of giving information about these variants of parotid tumors in pediatrics, which, despite their rareness, represent a high risk group when occur. Seven patients were diagnosed, of whom 3 were pleomorphic adenomas, one adenocarcinoma, one mucoepidermoid carcinoma of the gland, one parotid Hodgkin lymphoma and one mixed tumor with atypical cells of the gland. The onset of all the tumors was the presence of a parotid mass in 6 asymptomatic cases and in one case suffering local pain. They were all performed gland ultrasound and aspiration fine needle biopsy. Males prevailed over the females (ratio of 5:2) and the average age of presentation was 12.3 years. Surgery is the main therapeutic weapon in most of cases. It was recommended to closely follow the patients because of their high rate of local recurrence

  4. Malaria in pregnancy; facts from the parasitology laboratory: a ten-year study in Abuja, North Central Nigeria

    Directory of Open Access Journals (Sweden)

    Ibecheozor, N.K.O

    2014-09-01

    Full Text Available Malaria, which is transmitted by female Anopheles mosquitoes, is the major cause of mortality among the pregnant women in the sub-Saharan Africa. A ten year study of malaria in pregnancy was carried out in Abuja, North Central Nigeria. Thick and thin blood films were stained with the Giemsa methodology. Of the 16760 pregnant women blood samples, 4571 (27.3% were positive for malaria parasites caused by Plasmodium falciparum. Of the 4571 positive cases, 75 (1.7% had parasite density of >5000 parasites/µl of blood; 148 (3.2% had between 500-5000 parasites/µl of blood; 520 (11.4% had between 50 - 500 parasites/µl of blood; while 3828 (83.7% had between 5-50 parasites/µl of blood. With the current estimate of over 4500 deaths of pregnant women in Nigeria due to malaria annually, we must make deliberate efforts to stop these unacceptable and painful losses. The continued use of malaria rapid diagnostic tests (M-RDTs methodologies should be discontinued because of its negative implications. Therefore, the microscopic laboratory diagnostic component should be included in ANC at all level of health care facility.

  5. Ulcerated necrobiosis lipoidica as a rare cause for chronic leg ulcers: case report series of ten patients.

    Science.gov (United States)

    Franklin, Cindy; Stoffels-Weindorf, Maren; Hillen, Uwe; Dissemond, Joachim

    2015-10-01

    Necrobiosis lipoidica is a rare granulomatous disorder of the skin. In up to 30% of the affected patients it can lead to ulcerations, which can impair the quality of life and are also very difficult to treat. Its pathogenesis is not fully understood. Only few studies focussing on necrobiosis lipoidica can be found, but none of them focus on ulcerated necrobiosis lipoidica. Therefore, we collected demographic data and comorbidities and assessed treatment options for patients with ulcerated necrobiosis lipoidica. Data of patients who were treated in the wound care centre of the University Hospital of Essen for ulcerated necrobiosis lipoidica over the past 10 years were retrospectively analysed. Hence, data of altogether ten patients (nine women and one man) with ulcerated necrobiosis lipoidica were collected. Of these, 70% of the patients had diabetes mellitus of which 30% had type I diabetes and 40% had type II diabetes; 60% of the patients suffered from arterial hypertension, obesity and hypercholesterolaemia; 40% of the patients suffered from psychiatric disorders such as depression and borderline disorder. Our clinical data demonstrate an association of ulcerated necrobiosis lipoidica and aspects of metabolic syndrome. This leads to a conclusion that ulcerating necrobiosis lipoidica can be seen as part of a generalised inflammatory reaction similar to the inflammatory reaction already known in the pathophysiology of rheumatoid diseases or psoriasis. In patients with clinical atypical painful ulcerations, necrobiosis lipoidica should be considered as a possible differential diagnosis. Therapists should be aware of associated aspects in patients with ulcerated necrobiosis lipoidica who besides diabetes often suffer from other aspects of a metabolic syndrome with increased cardiovascular risk factors. Therefore, these related comorbidities should also be diagnosed and treated. PMID:24119190

  6. Equity in HIV testing: evidence from a cross-sectional study in ten Southern African countries

    Directory of Open Access Journals (Sweden)

    Mitchell Steven

    2010-09-01

    Full Text Available Abstract Background HIV testing with counseling is an integral component of most national HIV and AIDS prevention strategies in southern Africa. Equity in testing implies that people at higher risk for HIV such as women; those who do not use condoms consistently; those with multiple partners; those who have suffered gender based violence; and those who are unable to implement prevention choices (the choice-disabled are tested and can have access to treatment. Methods We conducted a household survey of 24,069 people in nationally stratified random samples of communities in Botswana, Lesotho, Malawi, Mozambique, Namibia, South Africa, Swaziland, Tanzania, Zambia, and Zimbabwe. We asked about testing for HIV in the last 12 months, intention to test, and about HIV risk behaviour, socioeconomic indicators, access to information, and attitudes related to stigma. Results Across the ten countries, seven out of every ten people said they planned to have an HIV test but the actual proportion tested in the last 12 months varied from 24% in Mozambique to 64% in Botswana. Generally, people at higher risk of HIV were not more likely to have been tested in the last year than those at lower risk, although women were more likely than men to have been tested in six of the ten countries. In Swaziland, those who experienced partner violence were more likely to test, but in Botswana those who were choice-disabled for condom use were less likely to be tested. The two most consistent factors associated with HIV testing across the countries were having heard about HIV/AIDS from a clinic or health centre, and having talked to someone about HIV and AIDS. Conclusions HIV testing programmes need to encourage people at higher risk of HIV to get tested, particularly those who do not interact regularly with the health system. Service providers need to recognise that some people are not able to implement HIV preventive actions and may not feel empowered to get themselves tested.

  7. Innovation for Sustainable Tourism : International Case Studies

    OpenAIRE

    Carlsen, Jack; Edwards, D; P. Forde

    2008-01-01

    Innovation is the key to responding to the future challenges that confront all sectors of society and the economy, and especially in tourism. Within tourism, there are numerous corporations and destinations around the world that are responding to the ecological, social and economic challenges and making the transformation toward sustainability through innovation. This book assembles ten case studies of large and small enterprises and destinations in developed and developing nations that are p...

  8. Paisagens rurbanas ou a tensão entre práticas rurais e valores urbanos na morfogênese dos espaços públicos de sedes de municípios rurais. Um estudo de caso. / Rurban landscapes: tension between rural practices and urban values in the morphogenesis of public spaces of seats of rural municipalities. A case study

    Directory of Open Access Journals (Sweden)

    Gisela Barcellos de Souza

    2009-08-01

    Full Text Available This article is interested in the deterioration of limits between rural and urban spaces in seats ofsmall rural municipalities. Based in a case study – a city of less than 3 thousand inhabitants – thisarticle postulates that the inadequate nomination of the seat of smaller rural municipalities as a“city” could to generate profound changes in townscape and in theirs representations, which bythe inscription of urban values and rural practices in its territory allows the configuration of arurban landscape.

  9. Early detection, early symptom progression and symptomatic remission after ten years in a first episode of psychosis study

    DEFF Research Database (Denmark)

    Simonsen, Erik; ten Velden Hegelstad, Wenche

    2013-01-01

    Background: Poor symptom outcome remains a challenge in psychosis: At least 50% of first-episode patients continue to have positive and/or negative symptoms after ten years. Objective: To investigate rates, early predictors and early symptom progression of long-term non-remitted psychosis in an early detection study. Methods: Symptomatic remission according to new international criteria was assessed in 174 patients at ten-year follow-up. Remitted and non-remitted patients were compared on early symptom progression, and logistic regression was applied to predict non-remission. Results: At ten years, 50% of patients were in symptomatic remission. Non-remission was predicted by positive symptoms at inclusion and during the first year of treatment. Of individual symptoms only hallucinations were significantly predictive of ten-year non-remission. Early symptom differences were not reflected by differences in treatment. Conclusions: Long-term symptomatic non-remission is associated with early positive symptoms. More assertive intervention may be needed in patients who do not respond robustly in the first year of treatment, whether or not they have been detected “early”.

  10. Prediction of Parkinson's disease subsequent to severe depression: a ten-year follow-up study.

    Science.gov (United States)

    Walter, Uwe; Heilmann, Robert; Kaulitz, Lara; Just, Tino; Krause, Bernd Joachim; Benecke, Reiner; Höppner, Jacqueline

    2015-06-01

    Major depressive disorder (MDD) has been associated with an increased risk of subsequent Parkinson's disease (PD) in case-control and cohort studies. However, depression alone is unlikely to be a useful marker of prodromal PD due to its low specificity. In this longitudinal observational study, we assessed whether the presence of other potential markers of prodromal PD predicts the subsequent development of PD in MDD patients. Of 57 patients with severe MDD but no diagnosis of PD who underwent a structured interview, olfactory and motor investigation and transcranial sonography at baseline, 46 (36 women; mean age 54.9 ± 11.7 years) could be followed for up to 11 (median, 10) years. Three patients (2 women; age 64, 65 and 70 years) developed definite PD after 1, 7, and 9 years, respectively. The combined finding of mild asymmetric motor slowing, idiopathic hyposmia, and substantia nigra hyperechogenicity predicted subsequent PD in all patients who could be followed for longer than 1 year. Out of the whole study cohort, only the subjects with subsequent PD presented with the triad of asymmetric motor slowing, idiopathic hyposmia, and substantia nigra hyperechogenicity in combination with at least two out of four reportable risk factors (family history of PD, current non-smoker, non-coffee drinker, constipation) at baseline investigation. Post-hoc analysis revealed that additional rating of eye and eye-lid motor abnormalities might further improve the prediction of PD in larger cohorts. Findings of this pilot-study suggest that MDD patients at risk of subsequent PD can be identified using an inexpensive non-invasive diagnostic battery. PMID:25217967

  11. STRUCTURED CASE REVIEW STUDY.

    Science.gov (United States)

    MILLER, LEONARD A.; MUTHARD, JOHN E.

    THIS STUDY EXAMINES A PROCEDURE FOR USING THE WRITTEN CASE RECORD AS A CRITERION FOR EVALUATING REHABILITATION COUNSELOR PERFORMANCE IN STATE "DVR" (STATE-FEDERAL GENERAL VOCATIONAL REHABILITATION PROGRAM) AGENCIES. THE RESEARCHERS OUTLINE CERTAIN OBJECTIVES (TECHNICAL, AGENCY SERVICES, AND STAFF DEVELOPMENT) AS DESIRABLE IN THE EVALUATION…

  12. Prague Case Study Report.

    Czech Academy of Sciences Publication Activity Database

    Kostelecký, Tomáš; Pato?ková, V?ra; Illner, Michal; Vobecká, Jana; ?ermák, Daniel

    Aarau : Centre for Democracy Studies Aarau (ZDA), 2014 - (Widmer, C.; Kübler, D.), s. 131-177 ISBN 978-3-9524228-2-3 R&D Projects: GA AV ?R IAA700280802 Institutional support: RVO:68378025 Keywords : urban neighbourhods * regeneration * Prague Subject RIV: AD - Politology ; Political Sciences http://www.zdaarau.ch/dokumente/en/ZDA_Working-Papers/No3_RUN_case-studies_2014.pdf

  13. Compliance with dietary recommendations in the population of Geneva, Switzerland: a ten-year trend study (1999-2009)

    OpenAIRE

    Marques-Vidal P.M.; De Abreu D.; Gaspoz J.M.; Guessous I

    2013-01-01

    Introduction: There is little information regarding compliance with dietary recommendations in Switzerland. Objectives: To assess the trends in compliance with dietary recommendations in the Geneva population for period 1999 - 2009. Methods: Ten cross-sectional, population-based surveys (Bus Santé study). Dietary intake was assessed using a self-administered, validated semi quantitative Food Frequency Questionnaire. Compliance with the Swiss Society for Nutrition recommendations for nutrient ...

  14. Triacylglycerols in some underutilised tropical seed oils 1. Systematic studies of ten oils

    International Nuclear Information System (INIS)

    Triacylglycerols composition of ten lesser known and underutilised tropical seed oils have been determined. The seed oils include Monodora tenuifolia, Monodora myristica, Colocynthis citrullus, Cyperus esculentus, Cucumeropsis edulis, Andenopus breviflorus, Telfairia occidentalis, Blighia sapida, Antiaris africana and Sesame indicum. In the Moreaceae family (M. tenuifolia, M. myristica) the dominant triacylglycerol are OPO/POO, LLO, OOL, and OOO. They accounted for over 60% of the total triacylglycerol content in the oils. In the Cyperaceae family (C. esculentus), OPP/POO, POL and OOO accounted for over 80% of the total triacylglycerol content. In the Cucurbitaceae family, SSP was the dominant triacylglycerol specie in A. breviflorus, while OPO/POO and OOO were the dominant species in C. citrullus and C. edulis. Blighia sapida recorded a different distribution of triacylglycerols composition. PLL occurred at the highest concentration, while other high molecular weight triacylglycerols were also identified in the oil. They include, SSA, OSA, LSA, OAA and LLA. Analysis of A. antiaris oil showed a different pattern in the distribution of the triacylglycerols. LaLaM, MMLa and LaLaLa accounted for about 80% of the total triacylglycerols. This result reflected the fatty acid composition of the oil. Lauric acid (C12:0) and Myristic acid (C14:0) accounted for 71.5% of the total fatty acid. The possible use of the oils as cocoa butter equivalents CBEs and cocoa butter substitutes CBSs are discussed. (author)

  15. Case study - Czechoslovakia

    International Nuclear Information System (INIS)

    In the lecture Case Study - Czechoslovakia with the sub-title 'Unified System of Personnel Preparation for Nuclear Programme in Czechoslovakia' the actual status and the current experience of NPP personnel training and preparation in Czechoslovakia are introduced. The above mentioned training system is presented and demonstrated by the story of a proxy person who is going to become shift engineer in a nuclear power plant in Czechoslovakia. (orig./HP)

  16. Corporate Governance. Case Studies

    OpenAIRE

    Manuel, Eduardo

    2007-01-01

    This paper pretends to do a theoretical approach of Corporate Governance, having as support some case studies about companies like Coca-Cola, Nokia, Microsoft, and Amazon.com. The methodology adopted for this work is based in information from these companies available in their websites and annual reports. I concluded that both companies show the corporate governance components according to their core business and their environmental business.

  17. Case Studies - Cervical Cancer

    Centers for Disease Control (CDC) Podcasts

    2010-10-15

    Dr. Alan Waxman, a professor of obstetrics and gynecology at the University of New Mexico and chair of the American College of Obstetricians and Gynecologists (ACOG) committee for the underserved, talks about several case studies for cervical cancer screening and management.  Created: 10/15/2010 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP), Division of Cancer Prevention and Control (DCPC).   Date Released: 6/9/2010.

  18. Die invloed van wanpersepsies ten opsigte van die geskiedenis van Suid-Afrika op grondeise: Die BaPhalane ba Ramokoka grondeis as gevallestudie / The influence of misperceptions on the history of South Africa: The BaPhalane ba Ramokoka land claim as case study

    Scientific Electronic Library Online (English)

    Anton C., van Vollenhoven.

    2012-12-01

    Full Text Available During the past few years, Archaetnos has been involved in various land claims, with a view to collecting historical, anthropological and archaeological information in order to determine the validity of such claims. This was done by doing deeds searches and studying archival material and anthropolog [...] ical literature, followed by a field survey where claimants indicated sites linked to their history and where they were interviewed. In some cases it was clear from the onset that misperceptions about South African history pertain. Even when information is correct, there is sometimes chronological chaos and in certain instances so-called "facts" are being fabricated. The above-mentioned information is used by the Land Claims Commission (LCC) to determine the merit of a claim. The lack of knowledge at this institution frequently results in cases being approved for the process even when such approval was clearly based on incorrect information. The land claim of the BaPhalane Ba Ramokoka community is one such example. In the article the reasons for land claims in general are listed. The merit of the BaPhalane claim, as well as the information obtained during the research process, is then discussed against this background. This is, however, not done in detail, as the article insteadfocuses on the general problem created by historical misperceptions. The findings of the research were that although the BaPhalane had a valid claim to at least four of the thirty-two farms listed, they had no valid claim to at least eighteen others. This was confirmed by the court judgement. It is concluded that the lack of knowledge at the Land Claims Commission results in many cases being unnecessarily investigated. This results in high costs, a waste of time and an unproductive system. It is therefore clear that information is required at a much earlier stage during the land claims process.

  19. Effect of transcutaneous electric nerve stimulation (TENS on hormones profile in subjects with primary dysmenorrhoea - a preliminary study

    Directory of Open Access Journals (Sweden)

    S. R. A. Akinbo

    2007-02-01

    Full Text Available Background & Objective: Primary dysmenorrhoea (PD is definedas the occurrence of painful menstrual cramps of uterine origin which occurs in the absence of any underlying disease. The pathogenesis is unclear, but uterine hyperactivity, elevated prostaglandin and leukotrienes levels, and hormonal level fluctuations have all been implicated. The objective of this study was to evaluate the effect of TENS on the hormones cortisol and prolactin in individuals with PD.Methods: Plasma levels of cortisol and prolactin were studied in twenty-one (21 subjects with PD by obtaining blood samples from each subject pre-and post-TENS therapy on the first day of menstruation. The mean age of subjects was 23 (+ 2 years.  The Visual Analogue Scale (VAS was used to assess the pre-and post-treatment pain intensity.  The TENS unit was applied for a duration of 30 minutes.Results: A paired t-test showed that there was an overall reduction in the mean cortisol and prolactin from  pre treatment values of 28.45µg/dl ((5.27 and 56.81ng/ml ((31.86 to post treatment values of 27.33µg/dl ((5.13 and 53.23ng/ml ((37.63 respectively. However, these differences were not statistically significant (P>0.05.  Pain intensity was significantly reduced comparing pre and post treatment VAS scores (P = 0.001.Conclusion: The probable mechanism by which TENS effected alterations in cortisol and prolactin levels and pain reduction in subjects with PD might be through the opioid-modulating analgesia system, which releases B-endorphins and other endogenous opiates in response to pain.  This is because there is a close relationship between B-endorphin, cortisol and neurons, which secrete dopamine into the hypothalamic-pituitary-portal system.

  20. Computational study of the structural and vibrational properties of ten and twelve vertex closo-carboranes

    International Nuclear Information System (INIS)

    Calculations using ab initio Hartree-Fock and Density Functional theories, the latter employing the B3LYP functional, in combination with a number of large standard basis sets ranging from 6-31G** to cc-pVDZ, have been performed on a series of ten and twelve vertex closo-carborane isomer species. Results obtained for optimized structural parameters and molecular properties are presented for 1,2-, 1,6- and 1,10-C2B8H10 and 1,2-, 1,7- and 1,12-C2B10H12 and compared, where possible, with both earlier theoretical data and experiment. Irrespective of the model chemistry chosen, the para-isomer in each class of carborane cluster is found to be the most stable species, corresponding to a structure in which the cage carbon atoms are positioned at diametrically opposed ends of the respective polyhedron. Boron-hydrogen and carbon-hydrogen bond lengths are found to change little on going from isomers of one particular cage size to another, supporting analogous conclusions previously established for small closo-carborane cages possessing five, six and seven vertices. The calculated vibrational spectra of the isomers of both decacarborane and dodecacarborane are seen to be similar to each other and reflect a high degree of rigidity within each cluster. Key polyhedral skeletal breathing modes along with characteristic boron-hydrogen and carbon-hydrogen stretching frequencies are identified in the spectra and compared with experiment. Thermochemical data relating to each species are also analyzed

  1. Computational study of the structural and vibrational properties of ten and twelve vertex closo-carboranes

    Energy Technology Data Exchange (ETDEWEB)

    Salam, A.; Deleuze, M.S.; Francois, J.-P

    2003-01-01

    Calculations using ab initio Hartree-Fock and Density Functional theories, the latter employing the B3LYP functional, in combination with a number of large standard basis sets ranging from 6-31G** to cc-pVDZ, have been performed on a series of ten and twelve vertex closo-carborane isomer species. Results obtained for optimized structural parameters and molecular properties are presented for 1,2-, 1,6- and 1,10-C{sub 2}B{sub 8}H{sub 10} and 1,2-, 1,7- and 1,12-C{sub 2}B{sub 10}H{sub 12} and compared, where possible, with both earlier theoretical data and experiment. Irrespective of the model chemistry chosen, the para-isomer in each class of carborane cluster is found to be the most stable species, corresponding to a structure in which the cage carbon atoms are positioned at diametrically opposed ends of the respective polyhedron. Boron-hydrogen and carbon-hydrogen bond lengths are found to change little on going from isomers of one particular cage size to another, supporting analogous conclusions previously established for small closo-carborane cages possessing five, six and seven vertices. The calculated vibrational spectra of the isomers of both decacarborane and dodecacarborane are seen to be similar to each other and reflect a high degree of rigidity within each cluster. Key polyhedral skeletal breathing modes along with characteristic boron-hydrogen and carbon-hydrogen stretching frequencies are identified in the spectra and compared with experiment. Thermochemical data relating to each species are also analyzed.

  2. Proton-nuclear magnetic resonance study of peracetylated derivatives of ten oligosaccharides isolated from human milk

    Energy Technology Data Exchange (ETDEWEB)

    Dabrowski, U.; Egge, H.; Dabrowski, J.

    1983-07-01

    Proton-nuclear magnetic resonance (NMR) spectra of peracetylated derivatives of ten structurally related oligosaccharides isolated from human milk were measured for solutions in CDCl3 at 360 MHz. The following oligosaccharides were investigated: Gal beta 1 leads to 4Glc-ol (1), GlcNAc beta 1 leads to 3Gal beta 1 leads to 4Glc-ol (2), Gal beta 1 leads to 4GlcNAc beta 1 leads to 3Gal beta 1 leads to 4Glc-ol (3), Gal beta 1 leads to 3GlcNAc beta 1 leads to 3Gal beta 1 leads to 4Glc-ol (4), Gal beta 1 leads to 3GlcNAc(4 comes from 1Fuc alpha) beta 1 leads to 3Gal beta 1 leads to 4Glc-ol (5), Fuc alpha 1 leads to 2Gal beta 1 leads to 3GlcNAc beta 1 leads to 3Gal beta 1 leads to 4Glc-ol (6), Fuc alpha 1 leads to 2Gal beta 1 leads to 3GlcNAc(4 comes from 1Fuc alpha)beta 1 leads to 3Gal beta 1 leads to 4Glc-ol (7), Fuc alpha 1 leads to 2Gal beta 1 leads to 4Glc-ol(3 comes from 1Fuc alpha) (8), and a 1:3 mixture of Fuc alpha 1 leads to 2Gal beta 1 leads to 4Glc-ol (9) and Gal beta 1 leads to 4Glc-ol(3 comes from 1Fuc alpha) (10). Owing to the strong downfield shifts of the resonances of protons linked to acetoxylated carbons, the problems of signal overlap are less severe and the spin systems of all constituent sugar residues can be assigned fully. The sites of glycosidic linkage can be recognized by the high-field position of the signals of protons linked to those sites; for example, type 1 (Gal beta 1 leads to 3GlcNAc) and type 2(Gal beta 1 leads to 4GlcNAc) saccharide chains can be distinguished. The sequence can be established by observing a nuclear Overhauser effect involving the anomomeric and the aglyconic proton.

  3. Tetanus in a Rural Setting of South-Western Nigeria: A Ten-Year Retrospective Study

    OpenAIRE

    Adekanle, O; O. Ayodeji; L Olatunde

    2009-01-01

    We review the records of 79 tetanus patients in two hospitals (one tertiary and one secondary level) in Owo, Ondo state, Nigeria from 1997 to 2006. The male: female ratio was 3:1. Ages were 14–70 years (mean 33.25 years, SD ±16.76). The overall case fatality rate (CFR), 32.91%, did was not significantly different in the two hospitals. CFR for men was 32.10% and for women 35.29%. The main factor indicative of bad prognosis was a short hospitalization period. It was observed that 30.38% of our ...

  4. Epidemiologic investigation of juvenile rheumatoid arthritis: a ten-year study

    Directory of Open Access Journals (Sweden)

    Abdolreza Malek

    2014-06-01

    Conclusion: The prevalence of JRA subgroups was different in Iran comparing with western countries and polyarticular disease was the most common subgroup in this study. Uveitis was less common in this study in comparison to studies in other coun-tries. There is no sex predilection in each subgroup of JRA.

  5. [A case of Stevens-Johnson syndrome (SJS) progressive toxic epidermal necrolysis (TEN) onset during hyposensitization therapy for pulmonary tuberculosis complicated with dermatomyositis].

    Science.gov (United States)

    Yamashita, Hiroyuki; Ueda, Yo; Takahashi, Yuko; Mimori, Akio

    2012-07-01

    A 58-year-old female with a history of dermatomyositis was receiving large oral doses of steroids. She had pulmonary tuberculosis and developed a fever, systemic exudative erythema, exanthema, and epidermolysis covering 30% of her body surface area while being treated with four agents, including isoniazid (INH) and rifampicin (RFP). Histopathologically, eosinophilic necrosis was observed in all layers of the epidermis and a diagnosis of Stevens-Johnson syndrome (SJS) progressive toxic epidermal necrolysis (TEN) was made. The drugs suspected in the drug-induced lymphocyte stimulation test (DLST) re-testing were INH and RFP, and the DLST was considered to be important during the recovery period as well as in the acute phase. Early treatment with plasma exchange therapy and large quantities of intravenous immunoglobulin (IVIG) was successful. Plasma exchange therapy and IVIG are extremely effective when SJS and TEN occur in a patient already on high-dose steroid therapy. Note that the incidence of SJS and TEN is believed to be higher in patients with collagen disease, such as in our case, as compared to the general population. PMID:22991850

  6. Western Perceptions of Hong Kong Ten Years on: A Corpus-Driven Critical Discourse Study

    Science.gov (United States)

    Cheng, Winnie; Lam, Phoenix W. Y.

    2013-01-01

    This article studies the Western perceptions of and relations with Hong Kong a decade after the reversion of the sovereignty from Britain to China in 1997. Previous studies have demonstrated that the West had a significantly negative view on the future of Hong Kong with respect to the handover. According to recent observations, however, the…

  7. Self-Report Stability of Adolescent Cigarette Use across Ten Years of Panel Study Data

    Science.gov (United States)

    Shillington, Audrey M.; Reed, Mark B.; Clapp, John D.

    2010-01-01

    This study is the first to examine adolescent cigarette report stability over 10 years. Six waves of data were utilized from the National Longitudinal Survey of Youth. This study examined internal/logical consistency and external consistency. Report stability was higher for lifetime use reports than the age of onset reports. Wave-by-wave…

  8. Congenital anomalies among live births in a polluted area. A ten-year retrospective study

    Directory of Open Access Journals (Sweden)

    Gianicolo Emilio Antonio Luca

    2012-12-01

    Full Text Available Abstract Background Congenital anomalies and their primary prevention are a crucial public health issue. This work aimed to estimate the prevalence of congenital anomalies in Brindisi, a city in southeastern Italy at high risk of environmental crisis. Methods This research concerned newborns up to 28 days of age, born between 2001 and 2010 to mothers resident in Brindisi and discharged with a diagnosis of congenital anomaly. We classified cases according to the coding system adopted by the European Network for the Surveillance of Congenital Anomalies (EUROCAT. Prevalence rates of congenital anomalies in Brindisi were compared with those reported by EUROCAT. Logistic regression models were adapted to evaluate the association between congenital anomalies and municipality of residence of the mother during pregnancy. Results Out of 8,503 newborns we recorded 194 subjects with congenital anomalies (228.2/10,000 total births, 1.2 times higher than the one reported by the EUROCAT pool of registries. We observed 83 subjects with congenital heart diseases with an excess of 49.1%. Odds Ratios for congenital heart diseases significantly increased for newborns to mothers resident in Brindisi (OR 1.75 CI 95% 1.30-2.35. Conclusions Our findings indicated an increased prevalence of Congenital Anomalies (especially congenital heart diseases in the city of Brindisi. More research is needed in order to analyze the role of factors potentially involved in the causation of congenital anomalies.

  9. A ten year Bluebird Trail study at Necedah National Wildlife Refuge

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report provides results from a bluebird and tree swallow monitoring study conducted at Necedah National Wildlife Refuge. For the years 19851994, nest boxes...

  10. Reactive hyperplastic lesions of the oral cavity: A ten year observational study on North Indian Population

    OpenAIRE

    Reddy, Vandana; Saxena, Susmita; Saxena, Sanjeev; Reddy, Munish

    2012-01-01

    Back ground: The aim of this study was to determine the frequency of focal reactive hyperplastic lesions of the oral cavity as reported in the Department of Oral Pathology and Microbiology, Subharti Dental College, Meerut and to compare these data with those of previously reported studies from other regions and countries. Material and Method: Patient records of the Department of Oral Pathology were retrieved during a 10 year period from 2001 to 2010. Data of all reactive hyperplasias namel...

  11. Multiple splenuculi - a case study

    International Nuclear Information System (INIS)

    Full text: A 79-year-old woman with chronic lymphocytic leukaemia (CLL) and thrombocytopenia secondary to chronic idiopathic thrombocytopenia (ITP) was referred for a denatured red blood cell study. Previous treatment included Prednisone, oral Cyclophosphamide and regular Intragam infusions as well as a splenectomy in 1996. The patient presented with multiple oral haemorrhages with active bleeding and petechiae on the chest wall. Her haemoglobin was 14.1g/dl, white cell count 6.6x10E9/l, and platelets 7x10E9/l. Her red blood cells were normochromic and contained moderate numbers of Howell-Jolly bodies, this was consistent with a post-splenectomy or hyposplenism. After the administration of autologous denatured technetium labelled red blood cells, an abdominal SPECT and planar images from the lung bases to mid femurs were acquired. The imaging showed evidence of approximately six small splenuculi in the left anterolateral aspect of the abdomen. A CT abdomen was performed following to assess suitability for surgery. Ten millimeter sections from the lung bases to the pelvis with intravenous and oral contrast demonstrated no splenuculi. As a result of the negative finding on CT, the patient was not considered for surgery as it was doubtful that surgeons would be able to locate the splenuculi. In conclusion, the denatured red blood cell study showed superior sensitivity and specificity for the detection of splenuculi. By the elimination of surgery, this case demonstrated the importance of correlation with other modalities in providing cost effective patient management. Copyright (2000) The Australian and New Zealand Society of Nuclear Medicine Inc

  12. KAIZEN – A case study

    Directory of Open Access Journals (Sweden)

    Manjunath Shettar

    2015-05-01

    Full Text Available The ultimate objective of manufacturing industries is to increase productivity with high quality. At present, many manufacturing companies are facing problems such as high quality rejection, high inventories, high lead time, high costs of production, and inability to cope with customer orders. By implementing and practicing the lean production system many problems can be solved without employing high-tech and high-touch approaches but by involving people on the shop floor in Kaizen activities. Kaizen is one of the powerful tools of lean manufacturing. Kaizen refers to continuous improvement in performance, cost and quality. Kaizen ensures that manufacturing processes become leaner and fitter, but eliminate waste (problem where value is added. The main objective of this paper is to provide a background on kaizen, present an overview of kaizen concepts that are used to transform a company into a high performing lean enterprise. A case study of implementation of Kaizen?s has been discussed.

  13. [The NonaSantfeliu study. Baseline assessment and ten years of follow-up].

    Science.gov (United States)

    Formiga, Francesc; Ferrer, Assumpta; Lombarte, Inés; Fernández, Coral

    2015-01-01

    NonaSantfeliu study: A review is presented of the studies that are part of the initial overall assessment and the studies performed during the 10 years of follow-up of a cohort of nonagenarians. It is a population-based study of 186 subjects, 76.5% women, mean age at baseline of 93.06 years, a quarter (26%) being institutionalized. The mean of baseline Barthel index was 60.8, and the mean for the Lobo's cognitive minimental was 21. Nonagenarian males with low comorbidity had more successful aging criteria than women with high comorbidity quantified with the Charlson Index. The survival rate at 10 years follow-up was very low, and 95.6% of the population had died. This represented an annual mortality rate of 9.5%. A common denominator on assessing all different annual cuts, is that the most important factors associated with mortality are those related to geriatric assessment, such as a function, cognition, dementia, and cumulative comorbidity and multiple medications, compared to more traditional risk factors described in younger populations. PMID:24854969

  14. Adjunct High Frequency Transcutaneous Electric Stimulation (TENS) for Postoperative Pain Management during Weaning from Epidural Analgesia Following Colon Surgery: Results from a Controlled Pilot Study.

    Science.gov (United States)

    Bjerså, Kristofer; Jildenstaal, Pether; Jakobsson, Jan; Egardt, Madelene; Fagevik Olsén, Monika

    2015-12-01

    The potential benefit of nonpharmacological adjunctive therapy is not well-studied following major abdominal surgery. The aim of the present study was to investigate transcutaneous electrical nerve stimulation (TENS) as a complementary nonpharmacological analgesia intervention during weaning from epidural analgesia (EDA) after open lower abdominal surgery. Patients were randomized to TENS and sham TENS during weaning from EDA. The effects on pain at rest, following short walk, and after deep breath were assessed by visual analog scale (VAS) grading. Number of patients assessed was lower than calculated because of change in clinical routine. Pain scores overall were low. A trend of lower pain scores was observed in the active TENS group of patients; a statistical significance between the groups was found for the pain lying prone in bed (p open colon surgery. Further studies are warranted in order to verify the potential beneficial effects from TENS during weaning from EDA after open, lower abdominal surgery. PMID:26541070

  15. The Oxford medial unicompartmental arthroplasty: a ten-year survival study.

    OpenAIRE

    Murray, DW; Goodfellow, JW; O'Connor, JJ

    1998-01-01

    Retrieval studies have shown that the use of fully congruent meniscal bearings reduces wear in knee replacements. We report the outcome of 143 knees with anteromedial osteoarthritis and normal anterior cruciate ligaments treated by unicompartmental arthroplasty using fully congruous mobile polyethylene bearings. At review, 34 knees were in patients who had died and 109 were in those who were still living. The mean elapsed time since operation was 7.6 years (maximum 13.8). We established the s...

  16. Case-control study of gastric cancer screening in Venezuela.

    OpenAIRE

    Pisani, P; Oliver, W. E.; Parkin, D M; Alvarez, N.; Vivas, J.

    1994-01-01

    A screening programme for early gastric cancer was introduced in the state of Tachira, Venezuela, in 1980. Screening was performed by photofluorography, using two mobile units. The efficacy of this programme in reducing mortality from stomach cancer was evaluated by means of a case-control study. Cases were 241 individuals who died from stomach cancer in the period 1985-89. Ten live controls per case were drawn from the electoral rolls, matched by sex, age and residence. Exposure to the scree...

  17. Reproduction and production in a buffaloes farm of the Marche region: a ten-year study

    Directory of Open Access Journals (Sweden)

    M. Pasquini

    2010-01-01

    Full Text Available Water buffalo milk reproductive and productive traits are fundamental to evaluate farm efficiency and dairy economy. Due to the buffalo cows’ long life these aspects are also important to assess the improvement of genetic animal potential and to reach optimal productive performance. Currently this knowledge is critical since the Italian cattle population is decreasing whereas the national buffalo sector is expanding; this trend is partially depending on the reconversion of some dairy cattle’ farms into buffalo cows’ farms. The present investigation was undertaken to study non-genetic factors affecting reproductive parameters and milk production traits in a farm located in a not traditional area for buffalo farming.

  18. Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization

    DEFF Research Database (Denmark)

    Bønnelykke, Klaus; Matheson, Melanie C; Pers, Tune H; Granell, Raquel; Strachan, David P; Alves, Alexessander Couto; Linneberg, Allan; Curtin, John A; Warrington, Nicole M; Standl, Marie; Kerkhof, Marjan; Jonsdottir, Ingileif; Bukvic, Blazenka K; Kaakinen, Marika; Sleimann, Patrick; Thorleifsson, Gudmar; Thorsteinsdottir, Unnur; Schramm, Katharina; Baltic, Svetlana; Kreiner-Møller, Eskil; Simpson, Angela; Pourcain, Beate St; Coin, Lachlan; Hui, Jennie; Walters, Eugene H; Tiesler, Carla M T; Duffy, David L; Jones, Graham; Ring, Susan M; McArdle, Wendy L; Price, Loren; Robertson, Colin F; Pekkanen, Juha; Tang, Clara S; Thiering, Elisabeth; Montgomery, Grant W; Hartikainen, Anna-Liisa; Dharmage, Shyamali C; Husemoen, Lise L; Herder, Christian; Kemp, John P; Elliot, Paul; James, Alan; Waldenberger, Melanie; Abramson, Michael J; Fairfax, Benjamin P; Knight, Julian C; Gupta, Ramneek; Thompson, Philip J; Holt, Patrick; Sly, Peter; Hirschhorn, Joel N; Blekic, Mario; Weidinger, Stephan; Hakonarsson, Hakon; Stefansson, Kari; Heinrich, Joachim; Postma, Dirkje S; Custovic, Adnan; Pennell, Craig E; Jarvelin, Marjo-Riitta; Koppelman, Gerard H; Timpson, Nicholas; Ferreira, Manuel A; Bisgaard, Hans; Henderson, A John

    2013-01-01

    Allergen-specific immunoglobulin E (present in allergic sensitization) has a central role in the pathogenesis of allergic disease. We performed the first large-scale genome-wide association study (GWAS) of allergic sensitization in 5,789 affected individuals and 10,056 controls and followed up the top SNP at each of 26 loci in 6,114 affected individuals and 9,920 controls. We increased the number of susceptibility loci with genome-wide significant association with allergic sensitization from thr...

  19. INTRAVENOUS PULSE CYCLOPHOSPHAMIDE TREATMENT OF LUPUS NEPHRITIS: A RETROSPECTIVE TEN YEARS STUDY

    Directory of Open Access Journals (Sweden)

    R. Ganji.

    1997-06-01

    Full Text Available Nephritis remains an important problem in patients with systemic lupus erythematosus (SLE. We conducted retrospective study to evaluate the efficiency of intravenous pulse cyclophosphamide in lupus nephritis: From 1983 to 1993, we reviewed 133 patients with biopsy proven lupus nephritis, 47 of them excluded because of short period of follow-up or defective laboratory data. Eighty six patients were treated with the following regimens: Sixty patients with intravenous pulse cyclophospham; 13 witli IV pulse methylprednisolone succinate, 8 with cyclosporine, 4 with azathioprine and one with oral prednisolone. Sixteen patients did not respond to IV cyclophosphamide. We evaluated renal biopsy, pretreatment mean arterial pressure (MAP, BUN, creatinine and proteinuria as-prognostic and risk factors of nonresponders. The results of this study showed that diffuse proliferative glomerulonephritis (DPGN had the poorest outcome and most of nonresponders (11/16, were of DPGN. Tliere was a correlation between initial serum creatinine level and response to IV cyclophosphamide, but there was no correlation between BUN, MAP, degree of proteinuria and response to IV cyclophosphamide. IV pulse cyclophosphamid was more effective than steroid alone in preventing renal failure in lupus nephritis.

  20. Ten years longitudinal study: comparison of abutment alveolar bone levels of overdenture patients

    Directory of Open Access Journals (Sweden)

    Brkovi?-Popovi? Snežana

    2006-01-01

    Full Text Available Aim: The aim of this study was to evaluate the effects of overdentures on the condition of alveolar bone around the remaining teeth over 10 years. Materials and Methods: After preparation of all the remaining abutment teeth in the lower jaw, overdentures were fabricated for 22 patients. The radiographs were made at the delivery stage, then 6 and 10 years after delivery. The radiographs were evaluated using the grid scale and the film holder made it possible to repeate x-ray procedure in every patient in the same manner. Results: We concluded that we achieved the maximum therapeutic effect. Conclusion: Good oral hygiene is the key of success with overdentures. .

  1. Using a natural abilities battery for academic and career guidance: a ten-year study.

    Science.gov (United States)

    Brown, Corrie C; Harvey, Stephen B; Stiles, Dori

    2011-01-01

    Over a period of 10 years, first-year students from 11 consecutive veterinary classes conducted a self-assessment using a natural abilities survey. The present study analyzes the data compiled from students' self-assessment results. As a group, veterinary students are exceptional problem solvers, either through inductive or deductive reasoning, and have strong spatial relations capacities. Veterinary students have a range of learning styles with design memory being the primary vehicle for information delivery and tonal memory being the least frequently used style overall. Information gained on each student's natural abilities can be used to guide effective career decision making and enhance prospects for long-term career satisfaction. PMID:22023979

  2. Apathy in first episode psychosis patients: a ten year longitudinal follow-up study

    DEFF Research Database (Denmark)

    Simonsen, Erik; Evensen, Julie

    2012-01-01

    BACKGROUND: Apathy is a common symptom in first episode psychosis (FEP), and is associated with poor functioning. Prevalence and correlates of apathy 10 years after the first psychotic episode remain unexplored. OBJECTIVE: The aims of the study were twofold: 1) to examine prevalence and predictors of apathy at 10 years, and 2) to examine the relationship between apathy at 10 years and concurrent symptoms, functioning and outcome, including subjective quality of life. METHODS: Three-hundred-and-one patients with FEP were included at baseline, 186 participated in the 10 year follow-up. Of these, 178 patients completed the Apathy Evaluation Scale (AES-S-Apathy). Patients were classified as having apathy (AES-S-Apathy?27) or not. The relationship between apathy and baseline variables (Demographics, Diagnosis, Duration of Untreated Psychosis), measures of symptomatology (Positive and Negative Syndrome Scale, Calgary Depression Scale for Schizophrenia), functioning (Global Assessment of Functioning Scale, Strauss Carpenter Level of Functioning Scale) and subjective quality of life (Lehman's Quality of Life Interview) were estimated through correlation analyses and blockwise multiple hierarchical regression analysis. RESULTS: Nearly 30% of patients met the threshold for being apathetic at follow-up. No baseline variables predicted apathy significantly at 10 years. Apathy was found to contribute independently to functioning and subjective quality of life, even when controlling for other significant correlates. CONCLUSIONS: Apathy is a common symptom in a FEP cohort 10 years after illness debut, and its presence relates to impaired functioning and poorer subjective quality of life.

  3. Evaluating the Cause of Death in Obese Individuals: A Ten-Year Medical Autopsy Study

    Science.gov (United States)

    Saab, Jad; Salvatore, Steven P.

    2015-01-01

    Background. Obesity is a growing public health problem associated with increased morbidity and rate of death. Postmortem examination is imperative to determine the cause of death, to detect clinically unsuspected disease entities, and consequently to determine the actual impact of obesity on patient mortality. Methods. A total of 849 adult autopsies were retrospectively reviewed. Obese (BMI ? 30?kg/m2) and nonobese patients were separately studied. The primary cause of death in each group was categorized into malignancy, infection, stroke, ischemic and nonischemic heart disease, pulmonary embolism, hemorrhage, and primary nonneoplastic diseases of different organ systems. Results. Of 849 autopsies, 32.3% were obese. The leading causes of death in the obese population were malignancy (31.4%), infection (25.9%), ischemic heart disease (12.8%), and pulmonary embolism (6.2%). Obese individuals were statistically more likely to die from pulmonary embolism and liver disease and less likely to die from neurologic diseases and nonischemic heart disease. Conclusion. Autopsies on obese individuals constitute a third of all adult medical autopsies in our center. Increased death rates in the obese due to pulmonary embolism and liver disease should receive special clinical attention. Autopsy findings in the obese population should contribute to overall premortem disease detection, prevention, and management. PMID:25653872

  4. Severe Allergic Reactions to Food in Norway: A Ten Year Survey of Cases Reported to the Food Allergy Register

    OpenAIRE

    Eliann Egaas; Martinus Løvik; Stensby, Berit A.; Ellen Namork; Fæste, Christiane K.

    2011-01-01

    The Norwegian Food Allergy Register was established at the Norwegian Institute of Public Health in 2000. The purpose of the register is to gain information about severe allergic reactions to food in Norway and to survey food products in relation to allergen labelling and contamination. Cases are reported on a voluntary basis by first line doctors, and submitted together with a serum sample for specific IgE analysis. The register has received a total of 877 reports from 1 July, 2000 to 31 Dece...

  5. Effect of TENS on pain in relation to central sensitization in patients with osteoarthritis of the knee: study protocol of a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Beckwée David

    2012-02-01

    Full Text Available Abstract Background Central sensitization has recently been documented in patients with knee osteoarthritis (OAk. So far, the presence of central sensitization has not been considered as a confounding factor in studies assessing the pain inhibitory effect of tens on osteoarthritis of the knee. The purpose of this study is to explore the pain inhibitory effect of burst tens in OAk patients and to explore the prognostic value of central sensitization on the pain inhibitory effect of tens in OAk patients. Methods Patients with knee pain due to OAk will be recruited through advertisements in local media. Temporal summation, before and after a heterotopic noxious conditioning stimulation, will be measured. In addition, pain on a numeric rating score, WOMAC subscores for pain and function and global perceived effect will be assessed. Patients will be randomly allocated to one of two treatment groups (tens, sham tens. Follow-up measurements will be scheduled after a period of 6 and 12 weeks. Discussion Tens influences pain through the electrical stimulation of low-threshold A-beta cutaneous fibers. The responsiveness of central pain-signaling neurons of centrally sensitized OAk patients may be augmented to the input of these electrical stimuli. This would encompass an adverse therapy effect of tens. To increase treatment effectiveness it might be interesting to identify a subgroup of symptomatic OAk patients, i.e., non-sensitized patients, who are likely to benefit from burst tens. Trial Registration ClinicalTrials.gov: NCT01390285

  6. Ten-Year Retrospective Longitudinal-Study of Student Perspectives on Value of REU

    Science.gov (United States)

    Slater, T. F.; Slater, S. J.

    2013-12-01

    For more than two decades, federal agencies have been enthusiastically supporting summer research experiences for undergraduates. These REU programs are tacitly intended to increase retention and provide "an important educational experience" for undergraduates, particularly women, minorities and underrepresented groups. Numerous authors (viz., Laursen, Lopatto, Dolan, among many others) have enthusiastically described positive impacts of summer REU programs from exit interview data. These results include enhanced persistence to pursue STEM careers and confirmed desire to attend graduate school in the field targeted by a particular REU. Perhaps surprisingly, negative student experiences are rarely described in the scholarly literature, but do appear in more informal publications (viz., Gueterma, 2007). One wonders how REU alumni, looking back over their entire collective portfolio of experiences, now perceive the educational value of their REU experience relative to their other educational experiences. To obtain a backwards-looking, reflective description from REU alumni on the value of their REU experiences, we conducted a 10-year, two-stage study was designed to explore the ways in which the REU acted as an educational experience for 51 women from a single geoscience sub-discipline. The first phase was an ex post facto longitudinal analysis of data, including multiple interviews with each participant during their REU, annual open-ended alumni surveys, faculty interviews, and extensive field notes, over a 10-year period. This analysis informed the second phase, a clinical interview. Over 10 hours of interviews with 8 participants were conducted and analyzed. These 8 participants were selected to represent a variety of career stages, and for their potential to reflect on a wide variety of educational experiences. Results from the interviews, done many years after their REU experience, indicate that the interviewees' REU did not provide a substantive educational experience related to the nature of scientific work, the scientific process, or the culture of academia when considered in a comparative context of students' other educational experiences. Results further indicated that the REU did not serve to transform participants' conceptions about themselves as situated in science, and learning gains with regard to other aspects of the self, were somewhat limited. Instead, the data suggests that these women arrived at the REU with pre-existing and remarkably strong conceptions in these areas, and that the REU did not functional to alter those states. These conceptions were frequently the result of interactions with mentors/scientists from middle school until well into the undergraduate period.

  7. Severe Allergic Reactions to Food in Norway: A Ten Year Survey of Cases Reported to the Food Allergy Register

    Directory of Open Access Journals (Sweden)

    Eliann Egaas

    2011-07-01

    Full Text Available The Norwegian Food Allergy Register was established at the Norwegian Institute of Public Health in 2000. The purpose of the register is to gain information about severe allergic reactions to food in Norway and to survey food products in relation to allergen labelling and contamination. Cases are reported on a voluntary basis by first line doctors, and submitted together with a serum sample for specific IgE analysis. The register has received a total of 877 reports from 1 July, 2000 to 31 December, 2010. Two age groups, small children and young adults are over-represented, and the overall gender distribution is 40:60 males-females. The legumes lupine and fenugreek have been identified as two “new” allergens in processed foods and cases of contamination and faults in production of processed foods have been revealed. The highest frequency of food specific IgE is to hazelnuts and peanuts, with a marked increase in reactions to hazelnuts during the last three years. The Food Allergy Register has improved our knowledge about causes and severity of food allergic reactions in Norway. The results show the usefulness of population based national food allergy registers in providing information for health authorities and to secure safe food for individuals with food allergies.

  8. Natural Learning Case Study Archives

    Science.gov (United States)

    Lawler, Robert W.

    2015-01-01

    Natural Learning Case Study Archives (NLCSA) is a research facility for those interested in using case study analysis to deepen their understanding of common sense knowledge and natural learning (how the mind interacts with everyday experiences to develop common sense knowledge). The database comprises three case study corpora based on experiences…

  9. Presentations to the Emergency Department Following Cannabis use-a Multi-Centre Case Series from Ten European Countries.

    Science.gov (United States)

    Dines, Alison M; Wood, David M; Galicia, Miguel; Yates, Christopher M; Heyerdahl, Fridtjof; Hovda, Knut Erik; Giraudon, Isabelle; Sedefov, Roumen; Dargan, Paul I

    2015-12-01

    Cannabis is the most commonly used illicit drug in Europe, and is generally regarded as having low acute toxicity. We present the findings of the first 6 months of data collection from the Euro-DEN project on presentations related to cannabis use to further understand the acute toxicity related to the use of cannabis. Data was extracted on clinical features, treatment and outcome from the Euro-DEN minimum dataset for all cases of acute recreational drug toxicity reported 1st October 2013 to 31st March 2014 for all cannabis-related presentations. Of 2198 presentations reported by 14 of the 16 Euro-DEN centres, 356 (16.2 %) involved cannabis either alone or together with other drugs/alcohol. There were 36 that involved lone use of cannabis (1.6 % of all presentations). Of the 35 non-fatal lone cannabis presentations, the most commonly reported features were neuro-behavioural (agitation/aggression 8 (22.9 %), psychosis 7 (20.0 %), anxiety 7 (20.0 %)) and vomiting 6 (17.1 %). Most patients (25, 71.4 %) received no treatment and 30 (85.7 %) were discharged/self-discharged from the ED. There was one fatality amongst these lone-cannabis cases: an 18-year-old male collapsed with an asystolic cardiac arrest whilst smoking cannabis and suffered hypoxic brain injury related to prolonged cardiac arrest. THC was detected in a urine sample taken at ED arrival; no other drugs were detected. Lone acute cannabis toxicity was typically associated with neuro-behavioural symptoms and vomiting. Although uncommon, severe toxicity including cardiovascular toxicity and death may be under-recognised, and it is important that Emergency Physicians are aware of this. PMID:25652342

  10. Theoretical study on ten ?-S states of Si2(-) anion: potential energy curves, spectroscopy and spin-orbit couplings.

    Science.gov (United States)

    Liu, Hui; Shi, Deheng; Sun, Jinfeng; Zhu, Zunlue

    2013-05-01

    The potential energy curves (PECs) of seventeen ? states generated from the ten ?-S states of the Si2(-) anion are studied in detail using an ab initio quantum chemical method for the first time. The PECs are calculated for internuclear separations from 0.10 to 1.20 nm by the complete active space self-consistent field method, which is followed by the internally contracted multireference configuration interaction approach with the Davidson modification. The spin-orbit coupling is accounted for by the Breit-Pauli Hamiltonian. Core-valence correlation and scalar relativistic corrections are considered. Core-valence correlation corrections are included using an aug-cc-pCVTZ basis set. Scalar relativistic correction calculations are made with the third-order Douglas-Kroll Hamiltonian approximation at the level of a cc-pV5Z basis set. Obvious effect of core-valence correlation corrections on the PECs is observed, in particular for the two lowest (2)?u and (2)?g(+) ?-S states. All the PECs are extrapolated to the complete basis set limit. The lowest (2)?u ?-S state is found to be the ground state of Si2(-) anion. The convergence observations of present calculations are made and the convergent behavior is discussed with respect to the basis set and level of theory. The effects of core-electron correlations on the energy splitting are studied by the all-electron aug-cc-pCVTZ basis set. Using these PECs, the spectroscopic parameters of ?-S and ? states involved are determined. The vibrational manifolds are evaluated for each ?-S and ? state of non-rotation Si2(-) anion. It shows that the spectroscopic parameters and molecular constants of ten ?-S and seventeen ? states reported here can be expected to be reliable predicted ones. PMID:23501942

  11. Teaching Pharmacology by Case Study.

    Science.gov (United States)

    Jordan, Sue

    1997-01-01

    Using pharmacology case studies with nursing students encourages theory-practice links and infuses real-life content. Cases provide rich qualitative data for evaluating curriculum. However, they are not a substitute for evidence-based practice. (SK)

  12. Safer Schools in the UK--A Case Study

    Science.gov (United States)

    Hayden, Carol; Holt, Amanda; Martin, Denise; Nee, Claire

    2011-01-01

    This article reports a research that is based on a European Safer Schools Partnership that included ten countries and specifically the UK case study which was located in London. The initiators of this partnership had been involved in early SSPs in the UK and the educationalists were very much focussed on work that would address problematic…

  13. Developing cloud business models: A case study on cloud gaming

    OpenAIRE

    Ojala, Arto; Tyrväinen, Pasi

    2011-01-01

    Cloud computing offers new ways for firms to operate in the global market so that even small firms can compete in markets traditionally dominated by multinational corporations. A case study considers how, over ten years, a small firm developed a successful business model to compete in computer gaming.

  14. Ten Myths about Spanking Children.

    Science.gov (United States)

    Straus, Murray A.

    One of a series of studies on corporal punishment of children, this paper argues that the reasons provided for the strong support of spanking are myths. Ten myths about spanking children are discussed by offering arguments that support the action and by quoting findings from studies that refute the arguments. The ten myths are: (1) spanking works…

  15. A TEN YEAR STUDY OF THE MANAGEMENT OF HAEMORRHOIDS AT A SECONDARY NURSING HOME IN SOUTH WEST NIGERIA

    OpenAIRE

    Omole Moses Kayode; Adegboye Oyebukola O.

    2012-01-01

    This retrospective study evaluated the different treatment options used in the management of haemorrhoids in a state government owned secondary hospital, Jericho Nursing Home, Ibadan, Nigeria. The study was conducted for a period of two weeks covering June 5th – 17th 2007.The total of 120 case notes available for patients treated for haemorrhoids were used and thoroughly studied. The case notes consist of Thirty four (28.3%) males and 86 (71.7%) females who were aged between 21-40 years 57(47...

  16. Measurement of implementation components ten years after a nationwide introduction of empirically supported programs – a pilot study

    Directory of Open Access Journals (Sweden)

    Ogden Terje

    2012-05-01

    Full Text Available Abstract Background Ten years after the nationwide dissemination of two evidence-based treatment programs, the status of the implementation components was evaluated in a cross-sectional study. The aim of the study was to pilot a standardized measure of implementation components by examining the factor structure, the reliabilities of the scores, and their association with implementation outcome variables. The aim was also to compare implementation profiles of the two evidence-based programs based on multi informant assessments. Methods The 218 participants in the study were therapists, supervisors, and agency leaders working with Parent Management Training, the Oregon model (PMTO, and Multisystemic Therapy (MST in Norway. Interviewers filled in an electronic version of the Implementation Components Questionnaire during a telephone interview. Results The factor analysis of the eight one-dimensional subscales resulted in an individual clinical-level factor and an organizational system-level factor. Age, experience, and number of colleagues in the workplace were negatively correlated with positive ratings of the implementation process, but the number of colleagues working with the same program predicted positive ratings. MST and PMTO had different implementation profiles and therapists, supervisors, and managers evaluated some of the implementation drivers significantly differently. Conclusions The psychometric quality of the questionnaire was supported by measures of internal consistency, factor analyses of the implementation components, and the comparisons of implementation profiles between programs and respondent groups. A moderate, but consistent association in the expected direction was found with the implementation outcome variables.

  17. Theory Testing Using Case Studies

    DEFF Research Database (Denmark)

    Møller, Ann-Kristina Løkke; Dissing Sørensen, Pernille

    2014-01-01

    testing using case studies, including the associated research goal, analysis, and generalisability. We argue that research designs for theory testing using case studies differ from theorybuilding case study research designs because different research projects serve different purposes and follow different......The appropriateness of case studies as a tool for theory testing is still a controversial issue, and discussions about the weaknesses of such research designs have previously taken precedence over those about its strengths. The purpose of the paper is to examine and revive the approach of theory...... research paths....

  18. Novel Loci Associated with PR Interval in a Genome-Wide Association Study of Ten African American Cohorts

    Science.gov (United States)

    Butler, Anne M.; Yin, Xiaoyan; Evans, Daniel S.; Nalls, Michael A.; Smith, Erin N.; Tanaka, Toshiko; Li, Guo; Buxbaum, Sarah G.; Whitsel, Eric A.; Alonso, Alvaro; Arking, Dan E.; Benjamin, Emelia J.; Berenson, Gerald S.; Bis, Josh C.; Chen, Wei; Deo, Rajat; Ellinor, Patrick T.; Heckbert, Susan R.; Heiss, Gerardo; Hsueh, Wen-Chi; Keating, Brendan J.; Kerr, Kathleen F.; Li, Yun; Limacher, Marian C.; Liu, Yongmei; Lubitz, Steven A.; Marciante, Kristin D.; Mehra, Reena; Meng, Yan A.; Newman, Anne B.; Newton-Cheh, Christopher; North, Kari E.; Palmer, Cameron D.; Psaty, Bruce M.; Quibrera, P. Miguel; Redline, Susan; Reiner, Alex P.; Rotter, Jerome I.; Schnabel, Renate B.; Schork, Nicholas J.; Singleton, Andrew B.; Smith, J. Gustav; Soliman, Elsayed Z.; Srinivasan, Sathanur R.; Zhang, Zhu-ming; Zonderman, Alan B.; Ferrucci, Luigi; Murray, Sarah S.; Evans, Michele K.; Sotoodehnia, Nona; Magnani, Jared W.; Avery, Christy L.

    2013-01-01

    Background The PR interval (PR) as measured by the resting, standard 12-lead electrocardiogram (ECG) reflects the duration of atrial/atrioventricular nodal depolarization. Substantial evidence exists for a genetic contribution to PR, including genome-wide association studies that have identified common genetic variants at nine loci influencing PR in populations of European and Asian descent. However, few studies have examined loci associated with PR in African Americans. Methods and Results We present results from the largest genome-wide association study to date of PR in 13,415 adults of African descent from ten cohorts. We tested for association between PR (ms) and approximately 2.8 million genotyped and imputed single nucleotide polymorphisms. Imputation was performed using HapMap 2 YRI and CEU panels. Study-specific results, adjusted for global ancestry and clinical correlates of PR, were meta-analyzed using the inverse variance method. Variation in genome-wide test statistic distributions was noted within studies (lambda range: 0.9–1.1), although not after genomic control correction was applied to the overall meta-analysis (lambda: 1.008). In addition to generalizing previously reported associations with MEIS1, SCN5A, ARHGAP24, CAV1, and TBX5 to African American populations at the genome-wide significance level (P<5.0×10?8), we also identified a novel locus: ITGA9, located in a region previously implicated in SCN5A expression. The 3p21 region harboring SCN5A also contained two additional independent secondary signals influencing PR (P<5.0×10?8). Conclusions This study demonstrates the ability to map novel loci in African Americans as well as the generalizability of loci associated with PR across populations of African, European and Asian descent. PMID:23139255

  19. Leukemia in women following radiotherapy for cervical cancer: ten-year follow-up of an international study

    International Nuclear Information System (INIS)

    An international collaborative study, with 69 references, of 31,219 women treated for cervical cancer from 30 radiotherapy centers in nine countries was conducted. Patients were followed clinically and with blood studies between 1960 and 1970, and 148,000 woman-years (WY) were accumulated. Among 28,490 women treated with either intercavitary radium, external radiation, or both, 134,000 WY were accumulated and 13 cases of leukemia were observed. On the basis of general population rates, 15.5 cases were expected. A twofold risk could thus be excluded, but a 1.4-fold risk remained possible. In absolute terms, risks larger than 0.1 leukemia cases per 106 WY-rad could be excluded. Among 2,729 cervical cancer patients not irradiated but similarly evaluated, 14,000 WY were accumulated and 2 cases of leukemia were observed as compared with 1.0 expected. In the interval 4-8 years after exposure, the period in which any leukemogenic effect might be most apparent, 7 cases of leukemia were observed among exposed patients as compared with 5.4 expected. The absence of an increased leukemia risk suggested that the radiation regimens used to treat cervical cancer are not so effective in inducing leukemia as are other radiation exposures that have been studied

  20. COMPARATIVE STUDY BETWEEN TITANIUM ELASTIC NAILING (TENS AND DYNAMIC COMPRESSION PLATING (DCP IN THE TREATMENT OF FEMORAL DIAPHYSEAL FRACTURES IN CHILDREN

    Directory of Open Access Journals (Sweden)

    Ramasubba Reddy

    2015-08-01

    Full Text Available BACKGROUND : Orthopaedic surgeons have long maintained that all children who have sustained a diaphyseal fracture of femur recover with c onservative treatment, given the excellent remodeling ability of immature bone in children. Angulations, shortenings and malrotations are not always corrected by conservative treatment. Of many surgical options, titanium elastic nailing has been the newer implant which is being used regularly. Although good results have been reported with elastic intramedullary nails, plate fixation continues to be a viable alternative in surgical treatment of femoral shaft fractures. However there are not many studies comp aring the efficiency of titanium elastic nailing and plating for femoral diaphyseal fractures in pediatric age group. AIM : The present study aims to compare the surgical management of diaphyseal fractures of femur in children with Dynamic Compression Plati ng versus Titanium Elastic Nailing. DESIGN : This is a prospective study . MATERIALS AND METHODS : This prospective study was conducted in a tertiary hospital. Patients who presented to the out - patient department and casualty of the hospital with femoral diap hyseal fractures during April 2012 to June 2014 were considered for the study. Subjects fulfilling the predetermined inclusion and exclusion criteria were included in the study. STATISTICAL METHODS : Fisher Exact test, Chi - Square Test, Student t test (Two t ailed, independent . RESULTS : Patients in the age group of 6 - 14 years were considered for the study, Patients were divided into two groups and treated with DCP/TENS. The duration of surgery, hospital stay, and, amount of blood loss was minimal in TENS grou p. Callus was seen early in TENS group. Radiological union was early in TENS group by 2 - 3 weeks. Outcome was better in patients treated with TENS (Excellent - 70%; Satisfactory – 30%; Poor - 0% in comparison to DCP (Excellent - 70%; Satisfactory - 25%; Poor - 5%. CO NCLUSION : TENS is more versatile and can achieve biological fixation, with minimal complications compared to DCP hence it is concluded that TENS is better procedure for fracture shaft femur in children than DCP

  1. Theory testing using case studies

    DEFF Research Database (Denmark)

    Dissing Sørensen, Pernille; Løkke Nielsen, Ann-Kristina

    Case studies may have different research goals. One such goal is the testing of small-scale and middle-range theories. Theory testing refers to the critical examination, observation, and evaluation of the 'why' and 'how' of a specified phenomenon in a particular setting. In this paper, we focus on...... the strengths of theory-testing case studies. We specify research paths associated with theory testing in case studies and present a coherent argument for the logic of theoretical development and refinement using case studies. We emphasize different uses of rival explanations and their implications...... for research design. Finally, we discuss the epistemological logic, i.e., the value to larger research programmes, of such studies and, following Lakatos, conclude that the value of theory-testing case studies lies beyond naïve falsification and in their contribution to developing research programmes...

  2. Theory testing using case studies

    DEFF Research Database (Denmark)

    Dissing SØrensen, Pernille; LØkke Nielsen, Ann-Kristina

    Case studies may have different research goals. One such goal is the testing of small-scale and middle-range theories. Theory testing refers to the critical examination, observation, and evaluation of the 'why' and 'how' of a specified phenomenon in a particular setting. In this paper, we focus on the strengths of theory-testing case studies. We specify research paths associated with theory testing in case studies and present a coherent argument for the logic of theoretical development and refinement using case studies. We emphasize different uses of rival explanations and their implications for research design. Finally, we discuss the epistemological logic, i.e., the value to larger research programmes, of such studies and, following Lakatos, conclude that the value of theory-testing case studies lies beyond naïve falsification and in their contribution to developing research programmes in a progressive way.

  3. Case Studies on Sustainable Buildings

    OpenAIRE

    Hui, Sam CM

    2005-01-01

    This web site is developed with the aim to promote sustainable design and planning of buildings. A knowledge base of case studies and resources has been established to illustrate the sustainable design strategies and features in realistic building projects all over the world. The database of case studies can be searched by project names, locations, design strategies and design features.

  4. Case Studies Reveal Camper Growth.

    Science.gov (United States)

    Brannan, Steve; Fullerton, Ann

    1999-01-01

    Case studies in the National Camp Evaluation Project and National Inclusive Camp Practices project used interviews with counselors and parents about camper's growth to yield qualitative data for camp program evaluation. The importance, methods, and benefits of case studies are described. Sidebars give examples of comments on perceived camper…

  5. Kickstarter - A Case Study

    OpenAIRE

    Willumsen, Ea Christina; Byg-Fabritius, Edith Ursula Tvede

    2013-01-01

    This paper is an investigation of the online crowdfunding platform Kickstarter, and discusses what makes a Kickstarter campaign successful. Two previous Kickstarter campaigns have been debated in focus groups interviews, as the basis of the study is a reception analysis of two focus group interviews. Ee apply theories from Schrøder (2000) and Batey (2008) to our analysis to study how the campaigns appeal to their backers. By drawing on ideas from Rogers (2003) and Pine & Gilmore (1998), we fu...

  6. Responses of streamflow and sediment load to climate change and human activity in the Upper Yellow River, China: a case of the Ten Great Gullies Basin.

    Science.gov (United States)

    Liu, Tong; Huang, He Qing; Shao, Mingan; Yao, Wenyi; Gu, Jing; Yu, Guoan

    2015-01-01

    Soil erosion and land desertification are the most serious environmental problems globally. This study investigated the changes in streamflow and sediment load from 1964 to 2012 in the Ten Great Gullies area of the Upper Yellow River. Tests for gradual trends (Mann-Kendall test) and abrupt changes (Pettitt test) identify that significant declines in streamflow and sediment load occurred in 1997-1998 in two typical gullies. A comparison of climatic variability before and after the change points shows no statistically significant trends in annual precipitation and potential evapotranspiration. Human activities have been very active in the region and during 1990-2010, 146.01 and 197.62 km2 of land were converted, respectively, to forests and grassland, with corresponding increases of 87.56 and 77.05%. In addition, a large number of check dams have been built up in the upper reaches of the ten gullies. These measures were likely responsible for the significant decline in the annual streamflow and sediment load over the last 49 years. PMID:26067511

  7. Case study - Argentina

    International Nuclear Information System (INIS)

    Antecedents and experience of nuclear activities in Argentina; the Atomic Energy Commission (CNEA). First development and research activities. Research reactors and radioisotopes plants. Health physics and safety regulations. - Feasibility studies for the first nuclear power plant. Awarding the first plant CNA I (Atucha I). Relevant data related to the different project stages. Plant performance. - Feasibility study for the second nuclear power plant. Awarding the second plant CNE (Central Nuclear Embalse). Relevant data related to established targets. Differences compared with the first station targets. Local participation. Plant performance. (orig./GL)

  8. Innovation for Sustainable Tourism : International Case Studies

    DEFF Research Database (Denmark)

    Carlsen, Jack

    2007-01-01

    Innovation is the key to responding to the future challenges that confront all sectors of society and the economy, and especially in tourism. Within tourism, there are numerous corporations and destinations around the world that are responding to the ecological, social and economic challenges and making the transformation toward sustainability through innovation. This book assembles ten case studies of large and small enterprises and destinations in developed and developing nations that are pursuing innovative practices that will enhance the sustainability of their operations. The chapters in this volume are based on primary and secondary research by the contributing authors and each chapter has been peer reviewed prior to publication. Cross-case analysis (Patton 1990) was also used to provide a framework for comparing and contrasting the different types and contexts of innovation and provide for an integrated overview of the drivers, barriers, processes and networks for innovation. The cases have been prepared for use in research and teaching of innovation, and the analysis and case notes are both designed to facilitate discussion and further investigation of innovation, not only in tourism, but in other economic sectors as well. Being an online publication, it is expected that updates in successive editions of this first book will add further to the description and analysis of innovation for sustainable tourism and hence provide a resource for those seeking to enhance the teaching, research and practice of innovation.

  9. Cervical neoplasia case studies

    Directory of Open Access Journals (Sweden)

    Eduard Crauciuc

    2012-09-01

    Full Text Available Cancer is nowadays one of the most important health problems. In Romania cancer is the second in generalmorbidity after cardio-vascular diseases, being followed by respiratory diseases, accidents and trauma. Considering thefact that cancer has an insidious start, a slow irreversible development towards physical and psychic invalidity, and that it affects both the person and the family and society, we can say it is very important to have a study of this illness from thesocial and medical point of view. The cytological examination offers, apart from the highlighting of the tumour cells, thepossibility of assessing the hormonal status, and also of identifying vaginal flora. Cervical cancer is a serious chroniccondition, which has great medical and social importance and has a severe evolution when detected in advanced stages.

  10. Pelvic floor disorders: Case study

    OpenAIRE

    Flood, Catherine

    2013-01-01

    Interactive case study discussions were an integral part of the program at the 3rd Annual Canadian Urology Forum (2013). The following is a summary of discussions pertaining to a case illustrating the difficulties in the management of pelvic floor disorders.

  11. Poroelastic behaviour of the degenerating human intervertebral disc: a ten-day study in a loaded disc culture system

    Directory of Open Access Journals (Sweden)

    KS Emanuel

    2015-06-01

    Full Text Available The intervertebral disc (IVD allows flexibility to the vertebral column, and transfers the predominant axial loads during daily activities. Its axial biomechanical behaviour is poroelastic, due to the water-binding and releasing capacity of the nucleus pulposus. Degeneration of the intervertebral disc presumably affects both the instantaneous elastic response to the load on the IVD and the subsequent interstitial flow of fluid. This study aims to quantify the poroelastic behaviour of the IVD and its change with degeneration, as defined by the magnetic resonance imaging-based Pfirrmann Score (PS. For a period of ten days, 36 human lumbar IVDs were loaded with a simulated physiological axial loading regime, while deformation was monitored. The IVDs responded to the loads with instantaneous elastic and slow poroelastic axial deformation. Several mechanical parameters changed throughout the first five days of the experiment, until the IVDs settled into a dynamic equilibrium. In this equilibrium, degeneration was significantly related to a decrease in disc height loss during the daytime high load phase (? = -0.49, and to a decrease in the rate of this deformation during the final half hour of each day (? = -0.53. These properties were related to the nucleus glycosaminoglycan/hydroxyproline (GAG/HYP ratio, rather than GAG content alone, indicating that remodelling of the extracellular matrix reduces poroelastic properties of the IVD. This implies that the degenerated discs have a reduced capacity to bind water and/or a reduced resistance against fluid flow. The resulting loss in hydrostatic pressure may further change cell behaviour in the nucleus pulposus.

  12. Teaching astronomy with case studies

    Science.gov (United States)

    Slater, Timothy F.

    2015-11-01

    Breaking the students into small, collaborative learning groups to solve a meaningful task together is one of the most successful and fully evaluated teaching techniques implemented over the last century. Although there are many ways to accomplish small group learning, a long-standing and consistently successful collaborative class activity is to use the case study teaching strategy. The use of case studies is common in medical schools and law schools, but not so common in the teaching of astronomy. Case studies create meaningful conversations among students and with the professor by focusing on life-like dilemmas to be solved. Case study tasks ask audience members to synthesize several ideas or evaluate scenarios that have not been explicitly presented to them in the lecture or in available readings.

  13. HYDROGEOLOGIC CASE STUDIES (CHICAGO, IL)

    Science.gov (United States)

    Hydrogeology is the foundation of subsurface site characterization for evaluations of monitored natural attenuation (MNA). Three case studies are presented. Examples of the potentially detrimental effects of drilling additives on ground-water samples from monitoring wells are d...

  14. Hydrogeologic Case Studies (Seattle, WA)

    Science.gov (United States)

    Hydrogeology is the foundation of subsurface site characterization for evaluations of monitored natural attenuation (MNA). Three case studies are presented. Examples of the potentially detrimental effects of drilling additives on ground-water samples from monitoring wells are d...

  15. HYDROGEOLOGIC CASE STUDIES (DENVER PRESENTATION)

    Science.gov (United States)

    Hydrogeology is the foundation of subsurface site characterization for evaluations of monitored natural attenuation (MNA). Three case studies are presented. Examples of the potentially detrimental effects of drilling additives on ground-water samples from monitoring wells are d...

  16. SENSORIA - Case studies scenario description

    OpenAIRE

    Gnesi, Stefania; ter Beek, Maurice H.; Baumeister, Hubert; Hoelzl, Matthias; Moiso, Corrado; Koch, Nora; Zobel, Angelika; Alessandrini, Michel

    2006-01-01

    The purpose of this work package is to provide a context of realistic case studies for developing intuitions that can feed and steer the research process according to the expectations of society and its economy, discussing and communicating ideas among partners and finally communicating research results to and getting feedback from the research community at large, both in industry and academia. Having in mind the relevance that these areas have in society and the economy, four case studies wi...

  17. Case Studies in Library Security

    CERN Document Server

    Shuman, Bruce A

    2002-01-01

    This book employs a familiar vehicle in library literature—the case study—but in a departure from the expected, takes that time-honored genre into a new dimension. Shuman uses the conversational narrative as a vehicle for portraying 40 security and safety issues that may arise in libraries, disturbing or vexing patrons and library staff members, alike. Unlike the traditional narrative approach of other case study books, in this work, each case is presented as a soliloquy, within a fictional but plausible library situation, whereby the protagonist uses his or her own colorful mode of expression

  18. Teaching Case: Enterprise Architecture Specification Case Study

    Science.gov (United States)

    Steenkamp, Annette Lerine; Alawdah, Amal; Almasri, Osama; Gai, Keke; Khattab, Nidal; Swaby, Carval; Abaas, Ramy

    2013-01-01

    A graduate course in enterprise architecture had a team project component in which a real-world business case, provided by an industry sponsor, formed the basis of the project charter and the architecture statement of work. The paper aims to share the team project experience on developing the architecture specifications based on the business case…

  19. A TEN YEAR STUDY OF THE MANAGEMENT OF HAEMORRHOIDS AT A SECONDARY NURSING HOME IN SOUTH WEST NIGERIA

    Directory of Open Access Journals (Sweden)

    Omole Moses Kayode

    2012-07-01

    Full Text Available This retrospective study evaluated the different treatment options used in the management of haemorrhoids in a state government owned secondary hospital, Jericho Nursing Home, Ibadan, Nigeria. The study was conducted for a period of two weeks covering June 5th – 17th 2007.The total of 120 case notes available for patients treated for haemorrhoids were used and thoroughly studied. The case notes consist of Thirty four (28.3% males and 86 (71.7% females who were aged between 21-40 years 57(47.5%, between 41-60 years 41(34.2% and between 61-80years 22(18.3%.Among the nursing mothers whose case notes were studied, 57(47.5% were pregnant while 63(52.5% were not pregnant.The nursing mothers’ occupations were marketing 4(3.3%, trading 36(30.0%, secretary 14(11.7%, teaching 16(13.3%, accounting 3(2.5%, student 7(5.8%, civil servant 6(5.0%, engineering 9(7.5% and retirees 8(6.7% with 17(14.2% not indicating their occupation.Treatment options reviewed showed that those treated with sitzbath were 58(20.7%, with oral liquid paraffin they were 62(22.1%, with Anusol suppositories they were 48(17.1%, with dietary advice they were 87(31.2%, with Surgery (haemorrhoidectomy they were 3(1.1% and with TCP ointment/Xylocaine gel they were 22(7.9%.Statistical analysis was done using the SPSS version 11.0 software programmer for frequency and cross tabulation.There is a need to improve on these treatment options. More innovative methods should be developed for effective treatment of haemorrhoids.

  20. Teaching pharmacology by case study.

    Science.gov (United States)

    Jordan, S

    1997-10-01

    This paper describes why case studies deserve a place in the centre of the bioscience curriculum, and how they have been used as a vehicle to improve care and save lives. A knowledge of drugs, their side-effects and interactions is becoming increasingly important to nurses. One powerful way to convey this information is the case study, which, despite its limitations, has the potential to endow difficult topics in therapeutics with the power of the narrative. The author suggests that case study projects encourage students to forge theory-practice links, related to their own specialist areas. When shared with their colleagues, these encourage the class by illustrating 'bioscience in action' and endowing the subject with the 'reality factor'. They also provide rich qualitative data for evaluating and delineating the curriculum. These case studies demonstrate the value of evidence-based practice; although case data is part of the evidence, it can never substitute for evidence-based practice. This paper builds on the findings of the author's PhD in postregistration nurse education; the examples described here are typical of 151 such cases in the research project. PMID:9370631

  1. Kenya Groundwater Governance Case Study

    OpenAIRE

    Mumma, Albert; Lane, Michael; Kairu, Edward; Tuinhof, Albert; Hirji, Rafik

    2011-01-01

    This report presents a case study on groundwater governance in Kenya. The objectives of the study were to: (a) describe groundwater resource and socioeconomic settings for four selected aquifers; (b) describe governance arrangements for groundwater management in Kenya; and (c) identify the relevance of these arrangements for planning and implementing climate change mitigation measures. The ...

  2. Case Study on Logistics Performance

    OpenAIRE

    Shahryar Sorooshian; Manimekalai Jambulingam; Javad Dodangeh

    2013-01-01

    The paper presents research carried out at a medium‐size manufacturing organization in east Asia. The study tries to highlight the importance of supply chain management; specifically, our aim for this study is to understand logistics and performance measurement in the logistics and supply chain, and we include a theoretical discussion of online data collected and a case study of the logistic performance of a real organization. The study also examines the performance of the selected company, i...

  3. Malformación de Chiari tipo I: evolución postoperatoria a dos años. Análisis de 10 casos / Chiari I malformation: postsurgical evolution after 2 years: Report of ten cases

    Scientific Electronic Library Online (English)

    L., Alvarez-Betancourt; J. A., García-Rentaría; S.J., López-Ortega; A., Caldera-Duarte.

    2005-02-01

    Full Text Available Objetivo. Describir la evolución de 10 pacientes con Malformación de Chiari tipo I (MCI), desde el punto de vista clínico y de imagen mediante resonancia magnética (RM). Método. A 10 pacientes con Malformación de Chiari se les realizó craniectomía suboccipital media, resección de arco posterior de C [...] 1 y plastia dural. A todos se les hizo un seguimiento clínico de dos años, y se hizo evaluación mediante RM a los seis meses del postoperatorio. Se correlaciona el tiempo de evolución preoperatoria, hallazgos de imagen mediante RM y la evolución clínica postoperatoria. Resultados. La evolución clínica postoperatoria mostró una mejoría importante en cuanto a función sensitiva, correlacionándose con la involución de la siringohidromielia que acompañaba a esos casos, mejoría parcial de sus funciones cerebelosas y, en menor grado, mejoría de la alteración motora. Las manifestaciones de atrofia muscular no tuvieron modificaciones en el seguimiento a dos años. Conclusiones. La MCI es una enfermedad congénita con múltiples manifestaciones clínicas que se van agravando conforme pasa el tiempo. Un diagnóstico oportuno y un tratamiento adecuado son indispensables para obtener los mejores resultado posibles desde el punto de vista neurológico. Abstract in english Objective To describe the clinical and radiological evolution of ten patients with Chiari I malformation (CIM), treated surgically. Method. Ten patients with Chiari I malformation underwent suboccipital craniectomy, laminectomy of C1 and dural patch grafting. All of them were followed for at least t [...] wo years. A magnetic resonance imaging was performed 6 months after surgery. Clinical preoperative evolution and time of installation, results of MRI and clinical postoperative evolution were correlated. Results. In postoperative clinical evolution, we noted an important improvement in sensitive function, decrease of the syringohydromielia and partial improvement of cerebellar functions. Improvement of the motor alteration was less marked. During the two years after treatment the muscular atrophy did not change. Conclusions. Chiari I malformation is a congenital disease with many clinical manifestations which usually increase with time. A suitable diagnostic studies as well as an appropriate treatment are needed to improve the neurological results.

  4. Case Study on Logistics Performance

    Directory of Open Access Journals (Sweden)

    Shahryar Sorooshian

    2013-05-01

    Full Text Available The paper presents research carried out at a medium‐size manufacturing organization in east Asia. The study tries to highlight the importance of supply chain management; specifically, our aim for this study is to understand logistics and performance measurement in the logistics and supply chain, and we include a theoretical discussion of online data collected and a case study of the logistic performance of a real organization. The study also examines the performance of the selected company, identifies the problems and provides recommendations for improvements. This study can be a guide for business advisers and those interested in analysing company performance, especially from a logistics viewpoint. We also suggest the methodology of this case study for those who want to have a better understanding of a business environment before starting their own business, or for benchmarking practice during strategic planning.

  5. Incidence of cancer in children residing in ten jurisdictions of the Mexican Republic: importance of the Cancer registry (a population-based study)

    International Nuclear Information System (INIS)

    In 1996, Mexico started to register cases of childhood cancer. Here, we describe the incidence of cancer in children, residing in ten Mexican jurisdictions, who were treated by the Instituto Mexicano del Seguro Social (IMSS). New cases of childhood cancer, which were registered prospectively in nine principal Medical Centers of IMSS during the periods 1998–2000 (five jurisdictions) and 1996–2002 (five jurisdictions), were analyzed. Personnel were specifically trained to register, capture, and encode information. For each of these jurisdictions, the frequency, average annual age-standardized incidence (AAS) and average annual incidence per period by sex and, age, were calculated (rates per 1,000,000 children/years). In total 2,615 new cases of cancer were registered, with the male/female ratio generally >1, but in some tumors there were more cases in females (retinoblastoma, germ cells tumors). The principal groups of neoplasms in seven jurisdictions were leukemias, central nervous system tumors (CNS tumors), and lymphomas, and the combined frequency for these three groups was 62.6 to 77.2%. Most frequently found (five jurisdictions) was the North American-European pattern (leukemias-CNS tumors-lymphomas). Eight jurisdictions had AAS within the range reported in the world literature. The highest incidence was found for children underless than five year of age. In eight jurisdictions, leukemia had high incidence (>50). The AAS of lymphomas was between 1.9 to 28.6. Chiapas and Guerrero had the highest AAS of CNS tumors (31.9 and 30.3, respectively). The frequency and incidence of neuroblastoma was low. Chiapas had the highest incidence of retinoblastoma (21.8). Germ-cell tumors had high incidence. The North American-European pattern of cancers was the principal one found; the overall incidence was within the range reported worldwide. In general but particularly in two jurisdictions (Yucatán and Chiapas), it will be necessary to carry out studies concerning the causes of cancer in children. Due to the little that is known about the incidence of cancer in Mexican children, it will be necessary to develop a national program to establish a cancer registry for the whole of the country

  6. Agile Transformation: A case study

    OpenAIRE

    Pitkänen, Antti

    2015-01-01

    Agile methods have been widely adopted in the software engineering industry. In addition, agile software development has been studied extensively during the past decade. In general, studies tend to recommend having experts working in small, self-organizing and cross-functional teams. However, the environment in an enterprise can comprise of multiple, interlinked pro- grams and dozens of teams working on them, which poses many challenges to adopting agile methods. In this case study, we st...

  7. BioFleet case studies

    International Nuclear Information System (INIS)

    These six case studies examined the use of different biodiesel blends as fuel supply sources for businesses in British Columbia (BC). In the first case study, 6 municipalities participated in a pilot program designed to compare the performance of biodiesel and diesel fuels. Each municipality operated 2 base vehicles running on conventional diesel along with 2 similar vehicles which used biodiesel. Real time emissions tests and analyses of the vehicles using biodiesel were also conducted by 2 of the participating municipalities. All municipalities participating in the study agreed to purchase significant volumes of biodiesel. The second case study described a pilot study conducted by the City of Vancouver's equipment services branch in 2004. As a result of the study, the city now has over 530 types of equipment that use biodiesel. The third case study described a program designed by TSI Terminals in Vancouver to assess the emission reduction impact of using biodiesel at its port facility. Six different pieces of equipment were used to confirm that biodiesel could be used throughout the terminal. Test results confirmed that biodiesel blends could be used to reduce emissions. Overall emissions were reduced by 30 per cent. The fourth case study described a waste renderer that used a fleet of 36 trucks to deliver raw products to its plants. The company made the decision to use only biodiesel for its entire fleet of trucks. Since July 2005, the company has logged over 1.7 million km using biodiesel blends. The fifth case study described a salmon hatchery that switched from diesel to biodiesel in order to reduce emissions. The biodiesel blends are used to fuel the hatchery's 2 diesel generators. The hatchery has reduced emissions of greenhouse gases (GHGs) by an estimated 1800 tonnes annually. The sixth case study described how the Township of Langley has started using biodiesel for its entire fleet of of approximately 250 pieces of equipment. The township has not encountered any operational differences in their field operations since switching to biodiesel. 26 figs

  8. Os Trigonum Syndrome: A Case Study

    Directory of Open Access Journals (Sweden)

    Yasemin Turan

    2013-05-01

    Full Text Available Os trigonum syndrome is one of the rare causes of posterior foot pain. Ostrigonum, which is placed at the posterior of talus, is an accessory bone. Ostrigonum syndrome causes back foot pain due to compression between talusand calcaneus. In this study, we present a case of os trigonum syndrome ,which is a rare disease and is generally missed. A 65-year-old female patientwith a complaint of left foot pain for the last 2 months persented to our outpatientclinic. In the physical examination, plantar flexion of the ankle andtoe was painful. Patient’s pain was evaluated by the visual analog scale andnoted as 8 cm. There was sensitivity at the posterior of talus during palpation.Os trigonum syndrome was diagnosed based on radiological examinationsand a physical therapy program consisting of transcutaneous electrical nervestimulation (TENS, cold pack, foot and ankle range of motion and strengtheningexercises was started. After the treatment, pain VAS decreased to 2cm,and then the patient was followed clinically. As in our case, os trigonum syndromeshould also be taken into consideration in patients complaining withposterior foot pain apart from other frequently encountered causes. In suchcases, physical therapy programs are very effective in pain management andin reducing the cost of treatment. Turk J Phys Med Rehab 2013;59:161-4.

  9. Case Studies in Sports Nutrition.

    Science.gov (United States)

    Clark, Nancy

    1988-01-01

    This article presents case studies of two athletes who wanted to affect a change in their body weight in order to enhance athletic performance. Each athlete's problem and the nutrition approach used to solve it are discussed. Caloric values of fast foods are listed. (JL)

  10. Equatorial jet - a case study

    Digital Repository Service at National Institute of Oceanography (India)

    Muraleedharan, P.M.; PrasannaKumar, S.

    Detailed EOF analysis of wind data reportEd. by Wunsch over Gan (00 degrees 41'S; 73 degrees 10'E) is made for the period 1963-70. The year 1964, which exhibited least variability from mean wind structure, has been chosen for the case study. EOF...

  11. eCompetence Case Studies

    DEFF Research Database (Denmark)

    Jensen, Helle Bækkelund

    In this paper we present some details of the processes undertaken in the European eCompetence Initiative. We present two illustrative and representative case studies. The research aims to identify and understand patterns of individual and organisational eCompetence approaches....

  12. The reflexive case study method

    DEFF Research Database (Denmark)

    Rittenhofer, Iris

    2015-01-01

    This paper extends the international business research on small to medium-sized enterprises (SME) at the nexus of globalization. Based on a conceptual synthesis across disciplines and theoretical perspectives, it offers management research a reflexive method for case study research of postnational...... business to analytically explore the global quality of SME....

  13. Experimental study of a fast plasma focus discharge operated in the range of tens of joules emitting neutrons

    International Nuclear Information System (INIS)

    In this doctoral research, a small plasma focus discharge operated at tens of joules and kilo amperes has been experimentally studied. This device produces a coaxial discharge by an electrode arrange which consists of an inner electrode, a cylindrical insulator, and an outer electrode. The discharge is driven by a capacitive generator and it is operated at pressures of some millibars. Typical electrical parameters of the device are T/4?150ns, 160 nF, 40 nH, 30-100J, 40-70kA. When Deuterium is used as filling gas, neutrons are produced by fusion reactions. The device, namely PF-50J, is one of the most extreme plasma focus reported in the literature to emit neutrons. The results of this work have demonstrated that the same dynamics found in larger machines (operated from kJ to MJ) is also found in this extremely low energy device which means that after the discharge is initiated, a plasma sheet is formed over the insulator. By the action of the Lorentz force, the plasma sheet moves axially. When the sheet reaches the top end of the inner electrode, it starts to implode radially to finally form a dense plasma column (pinch). Finally, the plasma column is disrupted 5-10ns after column formation. Shock piston velocities of the order of 104-105m/s were estimated from experiments for each discharge dynamical phase. Typical pinch densities of 1024-25m-3 were also observed in PF-50J. An interesting feature observed in this work is the formation of axial jet-like structures which appears at late times almost hundred nanoseconds after pinch disruption. These structures are composed by a metallic plasma which results from ablation of the inner electrode. The mechanism responsible for the formation of this kind of structure is still unknown, although evidence suggests that the phenomena is not related to the pinch formation process. One of the principal motivations of this thesis was to study the optimization for neutron emission in the PF-50J device. This plasma focus is expected to yield 103-104 neutrons per pulse when is operated with deuterium. Standard detection techniques, for example neutron activation detectors, present detection limits higher than 105 neutrons per pulse, so it was necessary to develop a measurement method for higher efficiency detectors based on the use moderated proportional counter tubes for the purpose of neutron optimization. In contrast to low rate continuous regime, this detectors show pulse piling up when irradiated with pulsed neutrons, which make impossible to count events with standard nuclear electronics. In this thesis, it is presented a detailed study of pulsed piling up statistics in the proportional counter and a complete characterization of the 3He tubes based detection system. Regarding that the net area of detector output signal is proportional to the number of detected events, a counting model was developed and thus a methodology for measurement of the neutron yield is proposed. Special emphasis was put on the sources of fluctuation that affects the measurement process, which are given by the counting statistics, piling up statistics, and background electrical noise. As a result, the methodology allows measurements uncertainties for pulsed D-D fusion neutrons lower than 30% in the range of Y ? 3x103n/shot, reducing in this way by almost two order of magnitude the detection limit of the state of art techniques. A theoretical study of the detection frequency or reproducibility for pulsed neutron sources is also presented. Comparisons with results in PF-50J show that theoretical models for reproducibility are reasonable high boundary estimations for the experimental values. The optimization study is presented in the last part of this work. Optimal conditions for neutron emission were experimentally obtained. An interesting finding is the observation of two regimes for pinch formation and neutron emission. The first regime is related to the pinch formation close to the first current maximum in the first quarter of period, while in the second one these phenomena are observed at higher press

  14. Probabilistic consequence study of residual radiological effects from a hypothetical ten-ton inadvertent nuclear yield. Weapons Safety Program

    International Nuclear Information System (INIS)

    In this paper we study the potential radiological consequences of a strategic bomber accident, in which one of the assumed on-board nuclear weapons explodes with an arbitrarily chosen 10-ton nuclear yield. The frequency of such an occurrence is infinitesimal. The safety design features in today s nuclear weapons' systems essentially forbid its occurrence. We have a chosen a military base which has the feature of being a representative combination of urban and rural populations. The assumed ''crash site'' is near the northwest comer of the military base, close to civilian housing located just across the street from the base. A worst case wind would be from the ESE (east south east). This would cause fission debris to be dispersed toward the largest population centers and, thus, would lead to the largest Pu ''collective'' doses (i.e., a dose integrated over time and summed over individuals). Also, if an ESE wind were blowing at accident time, some people in nearby housing could receive lethal gamma-ray doses from fallout before evacuation could occur. It is assumed only one weapon undergoes nuclear yield; the other on-board weapons would HE detonate and the Pu would be aerosolized and lofted. We assume an activity-size distribution and lofting similar to those used to predict fallout measured at NTS. The main thrust of our study is to provide estimates of probabilistic radiological risks to the population local to a strategic bomber crash site. The studied radiological consequences are: cloud-passage doses from Pu inhalation; doses from groundshine due to gamma-producing radionuclides; and areal contamination from Pu and the long-lived fission products Cs-137 and Sr-90

  15. 5. A ten year study of the treatment of malaria in pregnancy at a secondary hospital in south west Nigeria

    Directory of Open Access Journals (Sweden)

    M.K. Omole

    2011-02-01

    Full Text Available Malaria in pregnancy has remained a major public health problem in Nigeria. The treatment of malaria in pregnancy at the Lady of Apostles Catholic Hospital, Oluyoro, Oke-Ofa, Ibadan in South West Nigeria between 1999 and 2008 was studied retrospectively. The objective of the study was to assess the rational use of anti-malarial drugs in the treatment of malaria in pregnancy. A total of 580 case notes of patients were collected from the medical records department. The most prevalent age group of between 15 and 20 years accounted for two hundred and two (202 (34.8%, while the least prevalent age group of between 41 and 45 years was 10 (1.7%. Majority of the patients 299 (39.5% had secondary education, and those with tertiary education being 200 (34.5%. The gestational fetal age at which malaria infection was most prevalent was between 4 and 6 months, while the least prevalent gestational fetal age was between 7 and 9 months. There was a rapid but consistent decline in the use of Chloroquine forty eight (48 (23% from 1999, to 3 (5% in 2008. Sulfadoxine-Pyrimethamine 6 (3.8% was observed to have a steady rise in use during the years 1999 to 30 (18.8% in 2008. In 1999 and 2000 there was no ACT used. In 2001, 2 (0.9% ACTs were used and increased significantly (p>0.01 to fifty three (53 (24.8% in 2008. The community was averagely literacy and most of the women could therefore be trained on proper antenatal care through seminars and counseling thereby reducing the incidence of malaria in pregnancy.

  16. Ten Problems in Experimental Mathematics

    Energy Technology Data Exchange (ETDEWEB)

    Bailey, David H.; Borwein, Jonathan M.; Kapoor, Vishaal; Weisstein, Eric

    2004-09-30

    This article was stimulated by the recent SIAM ''100 DigitChallenge'' of Nick Trefethen, beautifully described in a recent book. Indeed, these ten numeric challenge problems are also listed in a recent book by two of present authors, where they are followed by the ten symbolic/numeric challenge problems that are discussed in this article. Our intent was to present ten problems that are characteristic of the sorts of problems that commonly arise in ''experimental mathematics''. The challenge in each case is to obtain a high precision numeric evaluation of the quantity, and then, if possible, to obtain a symbolic answer, ideally one with proof. Our goal in this article is to provide solutions to these ten problems, and in the process present a concise account of how one combines symbolic and numeric computation, which may be termed ''hybrid computation'', in the process of mathematical discovery.

  17. Organisational Communication: A Case Study

    OpenAIRE

    By Thomas A. Booth

    2008-01-01

    The organization chosen for this case study on organizational communication is a small political activists' organization for which the writer of this paper once volunteered. The organizational communication problem encountered was that the volunteer supervisor did not have projects ready during the scheduled volunteer time slots, and despite a thorough interview process to determine skill-need matches and prior verbal scheduling of volunteer times, this problem persisted for months. With the ...

  18. Institutional total energy case studies

    Energy Technology Data Exchange (ETDEWEB)

    Wulfinghoff, D.

    1979-07-01

    Profiles of three total energy systems in institutional settings are provided in this report. The plants are those of Franciscan Hospital, a 384-bed facility in Rock Island, Illinois; Franklin Foundation Hospital, a 100-bed hospital in Franklin, Louisiana; and the North American Air Defense Command Cheyenne Mountain Complex, a military installation near Colorado Springs, Colorado. The case studies include descriptions of plant components and configurations, operation and maintenance procedures, reliability, relationships to public utilities, staffing, economic efficiency, and factors contributing to success.

  19. Continuing education case study quiz.

    Science.gov (United States)

    2013-03-01

    Goal- The goal of this program is to educate pharmacists about the use of teriflunomide for the treatment of multiple sclerosis (MS). Objectives- At the completion of this program, the reader will be able to:Describe the pharmacology and pharmacokinetics of teriflunomide.Discuss the risks associated with the use of teriflunomide.Discuss the potential benefit of teriflunomide for an individual patient.Apply the information on the use of teriflunomide to a case study. PMID:24421468

  20. Stochastic efficiency: five case studies

    OpenAIRE

    Proesmans, Karel; Van den Broeck, Christian

    2015-01-01

    Stochastic efficiency is evaluated in five case studies: driven Brownian motion, effusion with a thermo-chemical and thermo-velocity gradient, a quantum dot and a model for information to work conversion. The salient features of stochastic efficiency, including the maximum of the large deviation function at the reversible efficiency, are reproduced. The approach to and extrapolation into the asymptotic time regime are documented.

  1. Ten steps or climbing a mountain: A study of Australian health professionals' perceptions of implementing the baby friendly health initiative to protect, promote and support breastfeeding

    OpenAIRE

    Sheehan Athena; Gribble Karleen; Schmied Virginia; Taylor Christine; Dykes Fiona C

    2011-01-01

    Abstract Background The Baby Friendly Hospital (Health) Initiative (BFHI) is a global initiative aimed at protecting, promoting and supporting breastfeeding and is based on the ten steps to successful breastfeeding. Worldwide, over 20,000 health facilities have attained BFHI accreditation but only 77 Australian hospitals (approximately 23%) have received accreditation. Few studies have investigated the factors that facilitate or hinder implementation of BFHI but it is acknowledged this is a m...

  2. Frequency and antimicrobial resistance patterns of bacteria implicated in community urinary tract infections: a ten-year surveillance study (2000–2009)

    OpenAIRE

    Linhares Inês; Raposo Teresa; Rodrigues António; Almeida Adelaide de

    2013-01-01

    Abstract Background Urinary tract infection (UTI) is one of the most common infectious diseases at the community level. In order to assess the adequacy of the empirical therapy, the prevalence and the resistance pattern of the main bacteria responsible for UTI in the community (in Aveiro, Portugal) was evaluated throughout a ten-year period. Methods In this retrospective study, all urine samples from patients of the District of Aveiro, in ambulatory regime, collected at the Clinical Analysis ...

  3. A case study of Impetigo

    Directory of Open Access Journals (Sweden)

    Mansouri P

    1993-05-01

    Full Text Available This is a report of a case study on 234 patients with impetigo who referred to Razi Dermatology Hospital from April to November, 1989. Treatment was started immediately after obtaining direct smear and performing culture and antibiotic sensitivity test. The most common organism responsible for impetigo was the coagulase-positive staphylococcus (71%. In 13.7% of the cases, the coagulase-negative staphylococcus was grown on culture media, but none of the cultures showed streptococcus as the main organism. Treatment was started with oral penicillin V, oral erythromycin, benzathine penicillin G injection, oral cephalexin, and topical fuccidin. Clinical and bacteriological evaluation after 3-7 days showed that it is preferable to use oral cephalexin instead of other protocols such as oral erythromycin, which has previously been the drug of choice for impetigo. In addition, topical fuccidin with a 75% curative rate was the first drug for treatment, with the same effect as the oral cephalexin

  4. Temporal patterns in count-to-ten fetal movement charts and their associations with pregnancy characteristics: a prospective cohort study

    Directory of Open Access Journals (Sweden)

    Winje Brita Askeland

    2012-11-01

    Full Text Available Abstract Background Fetal movement counting has long been suggested as a screening tool to identify impaired placental function. However, quantitative limits for decreased fetal movement perform poorly for screening purposes, indicating the need for methodological refinement. We aimed to identify the main individual temporal patterns in fetal movement counting charts, and explore their associations with pregnancy characteristics. Methods In a population-based prospective cohort in Norway, 2009–2011, women with singleton pregnancies counted fetal movements daily from pregnancy week 24 until delivery using a modified "count-to-ten” procedure. To account for intra-woman correlation of observations, we used functional data analysis and corresponding functional principal component analysis to identify the main individual temporal patterns in fetal movement count data. The temporal patterns are described by continuous functional principal component (FPC curves, with an individual score on each FPC for each woman. These scores were later used as outcome variables in multivariable linear regression analyses, with pregnancy characteristics as explanatory variables. Results Fetal movement charts from 1086 pregnancies were included. Three FPC curves explained almost 99% of the variation in the temporal data, with the first FPC, representing the individual overall counting time, accounting for 91% alone. There were several statistically significant associations between the FPCs and various pregnancy characteristics. However, the effects were small and of limited clinical value. Conclusions This statistical approach for analyzing fetal movement counting data successfully captured clinically meaningful individual temporal patterns and how these patterns vary between women. Maternal body mass index, gestational age and placental site explained little of the variation in the temporal fetal movement counting patterns. Thus, a perceived decrease in fetal movement should not be attributed to a woman’s basic pregnancy characteristics, but assessed as a potential marker of risk.

  5. Puma : a sponsorship case study

    OpenAIRE

    Vasconcelos, Tomás Garcia Pestana de

    2014-01-01

    This case study provides an overview of the sporting goods retail industry and the main players in the market and presents a decision-making moment from the Head of Sports Marketing Teamsport in PUMA regarding the company’s strategy for the year 2013, revolving around the pursuing one of the world’s leading football teams in order to get a sponsorship deal, or on the other hand it is better for the brand to make smaller deals with more teams with a smaller dimension. In the foo...

  6. Ten Top Tech Trends

    Science.gov (United States)

    McLester, Susan

    2008-01-01

    In this article, the author discusses the major technical issues, products, and practices of the day. The top ten tech trends are listed and discussed. These include: (1) data mining; (2) cyberbullying; (3) 21st century skills; (4) digital content; (5) learning at leisure; (6) personal responders; (7) mobile tools; (8) bandwidth; (9) open-source…

  7. Ten Top Tech Trends

    Science.gov (United States)

    McLester, Susan

    2008-01-01

    In this article, the author discusses the major technical issues, products, and practices of the day. The top ten tech trends are listed and discussed. These include: (1) data mining; (2) cyberbullying; (3) 21st century skills; (4) digital content; (5) learning at leisure; (6) personal responders; (7) mobile tools; (8) bandwidth; (9) open-source…

  8. A parathyroid scintigraphy case study

    International Nuclear Information System (INIS)

    Background: There has been much debate concerning the most suitable protocol for parathyroid scintigraphy; the merits of various radiopharmaceuticals versus the correct imaging protocol to visualise both ectopic and anatomically placed adenomas against the various equipment choices have been debated. Aim: To demonstrate, through the use of a case study, the necessity of changing imaging protocols for parathyroid scintigraphy where a definitive imaging diagnosis is absent in the face of strong clinical suspicion. Method: Use is made of Tc99mMIBI, full field chest scintigraphy, a clearly defined imaging protocol and SPECT imaging to locate ectopic parathyroid tissue in a female patient with significant symptoms of parathyroid hyperfunction. Results: A single hyperfunctioning adenoma is located in the pre-carinal area of the mediastinum. Using a radioguided surgical technique the hyperfunctioning tissue is excised and confirmed by histopathology. Conclusion: Whilst a dramatic reduction in patient symptoms was not seen immediately in this patient, the symptoms of the illness have been subsiding since January 2003. This case study demonstrates the necessity of changing imaging protocols for parathyroid scintigraphy where a definitive imaging diagnosis is absent in the face of strong clinical suspicion

  9. Five misunderstandings about Case-study Research

    DEFF Research Database (Denmark)

    Flyvbjerg, Bent

    This article examines five common misunderstandings about case-study research: (1) Theoretical knowledge is more valuable than practical knowledge; (2) One cannot generalize from a single case, therefore the single case study cannot contribute to scientific development; (3) The case study is most...

  10. Five misunderstandings about case study research

    DEFF Research Database (Denmark)

    Flyvbjerg, Bent

    This article examines five common misunderstandings about case-study research: (1) Theoretical knowledge is more valuable than practical knowledge; (2) One cannot generalize from a single case, therefore the single case study cannot contribute to scientific development; (3) The case study is most...

  11. Networks for Innovation for Sustainable Tourism : Case Studies and Cross-Case Analysis

    DEFF Research Database (Denmark)

    Liburd, Janne J.; Carlsen, Jack

    2013-01-01

    Innovation is key to responding to the future challenges that confront all sectors of society and the economy. Within tourism, there are numerous corporations and destinations around the world that are responding to the challenges posed by ecological, social, cultural and economic forces and making the transformation toward sustainability through innovation. Networks for Innovation in Sustainable Tourism assembles ten case studies of large and small enterprises and destinations in developed and developing nations that are pursuing innovative practices that will enhance the sustainability of their operations. The cases have been prepared for use in research and teaching of innovation, and the analysis and case notes are designed to facilitate discussion and further investigation of innovation, not only in tourism, but in other economic sectors as well.

  12. STS Case Study Development Support

    Science.gov (United States)

    Rosa de Jesus, Dan A.; Johnson, Grace K.

    2013-01-01

    The Shuttle Case Study Collection (SCSC) has been developed using lessons learned documented by NASA engineers, analysts, and contractors. The SCSC provides educators with a new tool to teach real-world engineering processes with the goal of providing unique educational materials that enhance critical thinking, decision-making and problem-solving skills. During this third phase of the project, responsibilities included: the revision of the Hyper Text Markup Language (HTML) source code to ensure all pages follow World Wide Web Consortium (W3C) standards, and the addition and edition of website content, including text, documents, and images. Basic HTML knowledge was required, as was basic knowledge of photo editing software, and training to learn how to use NASA's Content Management System for website design. The outcome of this project was its release to the public.

  13. Exact Diagonalization of the Hubbard Model: Ten-electrons on Ten-sites

    Directory of Open Access Journals (Sweden)

    Onaiwu N. Kingsley

    2013-09-01

    Full Text Available By exactly diagonalizing the Hubbard model for ten electrons on ten sites in a one-Dimensional (1D ring, we extend the study of Jafari (2008 to more than two electrons on two sites. We equally show the sparsity patterns of the Hamiltonian matrices for four- and eight-site problems and obtain the ground state energy eigenvalues for ten electrons on ten-sites. The technique we employ will be a good guide to a beginner/programmer.

  14. Ten?Year Blood Pressure Trajectories, Cardiovascular Mortality, and Life Years Lost in 2 Extinction Cohorts: the Minnesota Business and Professional Men Study and the Zutphen Study

    Science.gov (United States)

    Tielemans, Susanne M. A. J.; Geleijnse, Johanna M.; Menotti, Alessandro; Boshuizen, Hendriek C.; Soedamah?Muthu, Sabita S.; Jacobs, David R.; Blackburn, Henry; Kromhout, Daan

    2015-01-01

    Background Blood pressure (BP) trajectories derived from measurements repeated over years have low measurement error and may improve cardiovascular disease prediction compared to single, average, and usual BP (single BP adjusted for regression dilution). We characterized 10?year BP trajectories and examined their association with cardiovascular mortality, all?cause mortality, and life years lost. Methods and Results Data from 2 prospective and nearly extinct cohorts of middle?aged men—the Minnesota Business and Professional Men Study (n=261) and the Zutphen Study (n=632)—were used. BP was measured annually during 1947–1957 in Minnesota and 1960–1970 in Zutphen. BP trajectories were identified by latent mixture modeling. Cox proportional hazards and linear regression models examined BP trajectories with cardiovascular mortality, all?cause mortality, and life years lost. Associations were adjusted for age, serum cholesterol, smoking, and diabetes mellitus. Mean initial age was about 50 years in both cohorts. After 10 years of BP measurements, men were followed until death on average 20 years later. All Minnesota men and 98% of Zutphen men died. Four BP trajectories were identified, in which mean systolic BP increased by 5 to 49 mm Hg in Minnesota and 5 to 20 mm Hg in Zutphen between age 50 and 60. The third systolic BP trajectories were associated with 2 to 4 times higher cardiovascular mortality risk, 2 times higher all?cause mortality risk, and 4 to 8 life years lost, compared to the first trajectory. Conclusions Ten?year BP trajectories were the strongest predictors, among different BP measures, of cardiovascular mortality, all?cause mortality, and life years lost in Minnesota. However, average BP was the strongest predictor in Zutphen. PMID:25753924

  15. The immune system status under the effect of low-level radiation: studies within the ten-kilometer zone of Chernobyl disaster

    International Nuclear Information System (INIS)

    A study was made of the influence of high radiation contamination within the ten-kilometer zone of Chernobyl disaster on the structure and function of the immune system of mice. The cumulative radiation doses with respect to ?-radiation, were 0.024, 0.168 and 0.336 Gy. T-lymphocyte proliferation was shown to be activated with all radiation doses mentioned above but with doses of 0.024 and 0.168 Gy, helper T lymphocytes, and with 0.336 Gy, suppressor N-lymphocytes were primarilly activated. 9 refs., 7 figs., 2 tabs

  16. Ten steps to heaven

    OpenAIRE

    Chell, Edward

    2010-01-01

    Ten Steps to Heaven formed part of Fourteen Artists' Interventions, an exhibition held to mark the Swedenborg Society’s bicentennial celebration – a series of events including publications, lectures and presentations by writers including Simon Armitage, Iain Sinclair and A.S. Byatt. My contribution was a stair rail designed to have specific resonance to the site. Created for the bicentenary year, during which visitors encountered it as they moved through the building, my installation is now p...

  17. Personality Effects on Romantic Relationship Quality through Friendship Quality: A Ten-Year Longitudinal Study in Youths

    OpenAIRE

    Yu, Rongqin; Branje, Susan; Keijsers, Loes; Meeus, Wim H. J.

    2014-01-01

    This study examined whether individuals with different personality types (i.e., overcontrollers, undercontrollers, resilients) had different friendship quality development throughout adolescence. It also investigated whether personality types were indirectly related to romantic relationship quality in young adulthood, via friendship quality development in adolescence. The study employed six waves of longitudinal questionnaire data from Dutch youths who had a romantic relationship when they we...

  18. Powers of ten

    CERN Multimedia

    Pyramid FILMS

    1977-01-01

    Powers of Ten is a 1977 short documentary film written and directed by Charles Eames and his wife, Ray. The film depicts the relative scale of the Universe in factors of ten (see also logarithmic scale and order of magnitude). The film begins with an aerial image of a man reclining on a blanket; the view is that of one meter across. The viewpoint, accompanied by expository voiceover, then slowly zooms out to a view ten meters across ( or 101 m in standard form), revealing that the man is picnicking in a park with a female companion. The zoom-out continues, to a view of 100 meters (102 m), then 1 kilometer (103 m), and so on, increasing the perspectiveâ??the picnic is revealed to be taking place near Soldier Field on Chicago's waterfrontâ??and continuing to zoom out to a field of view of 1024 meters, or the size of the observable universe. The camera then zooms back in to the picnic, and then to views of negative powers of tenâ??10-1 m (10 centimeters), and so forth, until we are viewing a carbon nucl...

  19. Powers of ten

    CERN Document Server

    Innocenti, Pier Giorgio

    1979-01-01

    Powers of Ten is a 1977 short documentary film written and directed by Charles Eames and his wife, Ray. The film depicts the relative scale of the Universe in factors of ten (see also logarithmic scale and order of magnitude). The idea for the film appears to have come from the 1957 book Cosmic View by Kees Boeke. The film begins with an aerial image of a man reclining on a blanket; the view is that of one meter across. The viewpoint, accompanied by expository voiceover, then slowly zooms out to a view ten meters across ( or 101 m in standard form), revealing that the man is picnicking in a park with a female companion. The zoom-out continues, to a view of 100 meters (102 m), then 1 kilometer (103 m), and so on, increasing the perspectiveâ??the picnic is revealed to be taking place near Soldier Field on Chicago's waterfrontâ??and continuing to zoom out to a field of view of 1024 meters, or the size of the observable universe. The camera then zooms back in to the picnic, and then to views of negative pow...

  20. Analysis of Trend of Malaria Prevalence in the Ten Asian Countries from 2006 to 2011: A Longitudinal Study

    Science.gov (United States)

    Roy, Shongkour; Khatun, Tanjina

    2015-01-01

    Background. To control the malaria mortality, the global and national communities have worked together and produced impressive results in the world. Some of the Asian counties' malaria mortality rate is more compared to countries with high health facilities around the world. This paper's main aim is to describe trend of malaria cases and mortality in 10 Asian countries using the World Health Organization data. Methods. Malaria mortality data was collected systematically from WHO and UN database for the period 2006–2011. We estimated malaria mortality by age and countries. We also explored the dynamic relationships among malaria death rate, total populations, and geographical region using a map. During 2006–2011, the average malaria death per 10,000 population of all ages was 0.239 (95% CI 0.104 to 0.373), of children aged less than 5 year 1.143 (0.598 to 1.687), and of age greater than 5 years 0.089 (0.043 to 0.137) in Asian countries. Malaria prevalence per 10,000 populations steadily decreased from 486.7 in 2006 to 298.9 in 2011. Conclusion. The findings show that malaria mortality is higher for children aged less than 5 years compared with with adults selected in Asian countries except Sri Lanka. PMID:26693382

  1. Waves and turbulences studies in plasmas: ten years of research on quiescent plasmas at the Brazilian Space Research National Institute

    International Nuclear Information System (INIS)

    Quiescent plasmas generated by thermionic discharges and surface confined by multipole magnetic fields have been used in basic plasma research since 1973. The first machine was developed at UCLA (USA) to produce an uniform plasma for beam and waves studies in large cross section plasmas. A double quiescent plasma machine was constructed at the plasma laboratory of INPE in 1981, it began its operation producing linear ion-acoustic waves in an Argon plasma. Later on non linear ion acoustic waves and solitons were studied in plasma containing several species of negative and positive ions. The anomalous particle transport across multipole magnetic fields were also investigated. An anomalous resistivity associated with an ion acoustic turbulence is responsible for the formation of a small amplitude double-layer. The existence of a bootstrap mechanism is shown experimentally. Today, the main interest is toward the generation of Langmuir waves in non uniform plasmas. An experimental study on Langmuir wave generation using a grid system is been carried on. A magnetized quiescent plasma device for studies of whistle wave generation is been constructed. This machine will make possible future studies on several wave modes of magnetized plasmas. (author). 31 refs, 16 figs

  2. Cement Allergy: A Case Study.

    Science.gov (United States)

    Gamez, Marcia

    2015-01-01

    The purpose of this article was to educate nurses about the possibility of patients having an allergic reaction to polymethyl methacrylate (PMMA). Although rare, an allergic reaction to PMMA or the bone cement used to adhere the metal components of a total knee arthroplasty (TKA) to the bone can cause aseptic loosening of a TKA ( S. A. Edwards & J. Gardiner, 2007). The prevalence of PMMA allergies in the population has not been reported in the literature; therefore, no high-level research studies on the subject are available ( K. Kaplan, C. Della Valle, K. Haines, & J. D. Zuckerman, 2002). A case study and literature review was used to construct this article. The patient, L.W., a 61-year-old, white woman, is a nail technician with a history of right knee pain, stiffness, soreness, and a decreased range of motion for one and a half years following a TKA. The complications from a PMMA allergy could be avoided by adding one or two questions to the patient's history and physical form. A complete history could also do away with the need for additional testing and increased medical expenses for the patient and the healthcare system as a whole. PMID:26213878

  3. Disaster exposure as a risk factor for mental health problems, eighteen months, four and ten years post-disaster – a longitudinal study

    Science.gov (United States)

    2012-01-01

    Background Disaster experiences have been associated with higher prevalence rates of (mental) health problems. The objective of this study was to examine the independent relation between a series of single disaster experiences versus the independent predictive value of a accumulation of disaster experiences, i.e. a sum score of experiences and symptoms of distress and post-traumatic stress disorder (PTSD). Methods Survivors of a fireworks disaster participated in a longitudinal study and completed a questionnaire three weeks (wave 1), eighteen months (wave 2) and four years post-disaster (wave 3). Ten years post-disaster (wave 4) the respondents consisted of native Dutch survivors only. Main outcome measures were general distress and symptoms of PTSD. Results Degree of disaster exposure (sum score) and some disaster-related experiences (such as house destroyed, injured, confusion) were related to distress at waves 2 and 3. This relation was mediated by distress at an earlier point in time. None of the individual disaster-related experiences was independently related to symptoms of distress. The association between the degree of disaster exposure and symptoms of PTSD at waves 2 and 3 was still statistically significant after controlling for symptoms of distress and PTSD at earlier point in time. The variable ‘house destroyed’ was the only factor that was independently related to symptoms of PTSD at wave 2. Ten years after the disaster, disaster exposure was mediated by symptoms of PTSD at waves 2 and 3. Disaster exposure was not independently related to symptoms of PTSD ten years post-disaster. Conclusions Until 4 years after the disaster, degree of exposure (a sum score) was a risk factor for PTSD symptoms while none of the individual disaster experiences could be identified as an independent risk factor. Ten years post-disaster, disaster exposure was no longer an independent risk factor for symptoms of PTSD. Since symptoms of PTSD and distress at earlier waves perpetuate the symptoms at later waves, health care workers should aim their resources at those who still have symptoms after one and a half year post-disaster, to prevent health problems at medium and long-term. PMID:22989093

  4. Disaster exposure as a risk factor for mental health problems, eighteen months, four and ten years post-disaster – a longitudinal study

    Directory of Open Access Journals (Sweden)

    van den Berg Bellis

    2012-09-01

    Full Text Available Abstract Background Disaster experiences have been associated with higher prevalence rates of (mental health problems. The objective of this study was to examine the independent relation between a series of single disaster experiences versus the independent predictive value of a accumulation of disaster experiences, i.e. a sum score of experiences and symptoms of distress and post-traumatic stress disorder (PTSD. Methods Survivors of a fireworks disaster participated in a longitudinal study and completed a questionnaire three weeks (wave 1, eighteen months (wave 2 and four years post-disaster (wave 3. Ten years post-disaster (wave 4 the respondents consisted of native Dutch survivors only. Main outcome measures were general distress and symptoms of PTSD. Results Degree of disaster exposure (sum score and some disaster-related experiences (such as house destroyed, injured, confusion were related to distress at waves 2 and 3. This relation was mediated by distress at an earlier point in time. None of the individual disaster-related experiences was independently related to symptoms of distress. The association between the degree of disaster exposure and symptoms of PTSD at waves 2 and 3 was still statistically significant after controlling for symptoms of distress and PTSD at earlier point in time. The variable ‘house destroyed’ was the only factor that was independently related to symptoms of PTSD at wave 2. Ten years after the disaster, disaster exposure was mediated by symptoms of PTSD at waves 2 and 3. Disaster exposure was not independently related to symptoms of PTSD ten years post-disaster. Conclusions Until 4 years after the disaster, degree of exposure (a sum score was a risk factor for PTSD symptoms while none of the individual disaster experiences could be identified as an independent risk factor. Ten years post-disaster, disaster exposure was no longer an independent risk factor for symptoms of PTSD. Since symptoms of PTSD and distress at earlier waves perpetuate the symptoms at later waves, health care workers should aim their resources at those who still have symptoms after one and a half year post-disaster, to prevent health problems at medium and long-term.

  5. The effect of manganese on the central nervous system. On the basis of ten cases with hyperintensities in the globus pallidus and a part of the brainstem on T1-weighted magnetic resonance imaging

    International Nuclear Information System (INIS)

    We examined the effect of manganese (Mn) on the central nervous system, on the basis of ten cases with hyperintensities in the globus pallidus and a part of the brainstem on T1-weighted magnetic resonance imaging (MRI). These cases were divided into three groups; four cases with liver dysfunction, three cases with intravenous infusion containing Mn and three cases without any specific factor. Mn levels were measured in serum, whole blood and cerebrospinal fluid (CSF). As a result, their serum and CSF Mn levels were significantly higher (P<0.05 and P<0.01, respectively) than those of the control subjects, while their whole blood Mn levels were not significantly different. Single photon emission computed tomography demonstrated a decrease of the cerebral blood flow in the frontal lobe in four cases with the hyperintensities and in one of them the decrease improved after the disappearance of the hyperintensity. Oculogyric crisis in one case with intravenous infusion containing Mn and dystonia in one case without any specific factor also improved, when the hyperintensities disappeared. In the cases with T1-weighted MRI hyperintensities, it is important to measure serum and CSF Mn levels as well as to observe psychiatric and neurological symptoms. (author)

  6. Catalog of NASA-Related Case Studies

    Data.gov (United States)

    National Aeronautics and Space Administration — The OCKO has developed over 50 case studies to enhance learning at workshops, training, retreats and conferences. Case studies make mission knowledge attractive and...

  7. Culturally competent bioethics: analysis of a case study.

    Science.gov (United States)

    Gray, Ben

    2015-06-01

    This paper discusses the Saudi Arabian case by Abdallah Adlan and Henk ten Have, published in a 2012 issue of the Journal of Bioethical Inquiry, regarding a congenitally disabled child enrolled in a research project examining the genetics of her condition. During the course of the study, her father was found not to be genetically related, and the case discussed the dilemma between disclosing to the family all findings as promised in consent documents or withholding paternity information because of the likely severe social repercussions. Using Adlan and ten Have's example, this paper proposes a framework to consider cases outside of the conventional bioethics frame of reference, splitting the bioethical task into three elements: understanding the problem from the patient's and the clinician's perspective and then engaging in dialogue to decide what to do next. The process of dialogue between affected parties is vital. Presuming that there is a common morality undermines the effectiveness of the dialogue needed to find a resolution. PMID:26016616

  8. Using Time-on-Task Measurements to Understand Student Performance in a Physics Class: A Ten-Year Study

    Science.gov (United States)

    Stewart, John

    2015-04-01

    The amount of time spent on out-of-class activities such as working homework, reading, and studying for examinations is presented for 10 years of an introductory, calculus-based physics class at a large public university. While the class underwent significant change in the 10 years studied, the amount of time invested by students in weeks not containing an in-semester examination was constant and did not vary with the length of the reading or homework assignments. The amount of time spent preparing for examinations did change as the course was modified. The time spent on class assignments, both reading and homework, did not scale linearly with the length of the assignment. The time invested in both reading and homework per length of the assignment decreased as the assignments became longer. The class average time invested in examination preparation did change with the average performance on previous examinations in the same class, with more time spent in preparation for lower previous examination scores (R2 = 0 . 70).

  9. Modifiable cardiovascular disease risk factors as predictors of dementia death: pooling of ten general population-based cohort studies

    Science.gov (United States)

    2014-01-01

    Background With drug treatment for dementia being of limited effectiveness, the role of primary prevention, in particular the predictive value of modifiable cardiovascular disease risk factors, may warrant exploration. The evidence base is, however, characterised by discordant findings and is modest in size. Accordingly, we examined the association of modifiable cardiovascular disease risk factors with dementia death. Design and methods We pooled raw data from 10 UK general population-based prospective cohort studies within the context of an individual participant meta-analysis. Results A total of 103,764 men and women were followed up for a mean of 8 years giving rise to 443 dementia-related deaths and 2612 cardiovascular disease deaths. Cardiovascular disease mortality was, as anticipated, associated with the full range of risk factors under study, including raised blood pressure, smoking, diabetes, physical inactivity. By contrast, dementia death was related to very few of the cardiovascular disease risk factors: of those classified as modifiable, only smoking was associated with a raised risk and higher levels of non-HDL with a lower risk. Conclusions In the present individual participant meta-analysis, there was limited evidence that cardiovascular disease risk factors were related to dementia death. PMID:24886432

  10. Concentrated photovoltaics, a case study

    Directory of Open Access Journals (Sweden)

    Antonini Piergiorgio

    2014-01-01

    Full Text Available Concentrated Photovoltaics (CPV, once a niche technology, has now reached the maturity and reliability for large scale power generation. Especially in regions where temperatures are very high, the use of high efficiency triple junction solar cells with concentrating optics allows stable energy yield. Thus CPV can be seen as complementary and not in concurrence with silicon photovoltaics. The state of the art, the advantages and limitations of this technology will be shown. Among the main advantages of CPV is the possibility of a much higher energy supply, when compared to silicon photovoltaics, both comparing CPV and silicon with same area or the same installed power. The use of recycled and recyclable materials allows a more environmentally friendly production. The possibility to couple CPV with desalination facilities, energy storage will be analysed. As an example a case study of a CPV installation in Northern Italy is discussed. Here the use of mature technologies, derived from automotive and lighting sectors resulted in a simple and efficient module.

  11. Summary of case studies for cooperation mechanisms

    DEFF Research Database (Denmark)

    Longa, Francesco Dalla; Klinge Jacobsen, Henrik; Hansen, Lise-Lotte Pade; Tantareanu, Cristian; Caldes-Gomez, Natalia; Santamaria-Belda, Marta

    2012-01-01

    This document is a summary report highlighting the main aspect analyzed in the RES4LESS case studies. The document starts with an introductory chapter where the background that led to the selection of the case studies is outlined. In the following three chapters the case studies are presented, hi...

  12. Case Study: The Chemistry of Cocaine

    Science.gov (United States)

    Dewprashad, Brahmadeo

    2011-01-01

    This column provides original articles on innovations in case study teaching, assessment of the method, as well as case studies with teaching notes. This month's case study focuses on the chemistry of cocaine to teach a number of core concepts in organic chemistry. It also requires that students read and analyze an original research paper on…

  13. The association of microalbuminuria with mortality in patients with acute myocardial infarction. A ten-year follow-up study

    Directory of Open Access Journals (Sweden)

    Jan Skov Jensen

    2010-02-01

    Full Text Available Our study evaluates the long-term effect of microalbuminuria on mortality among patients with acute myocardial infarction. We followed 151 patients from 1996 to 2007 to investigate if microalbuminuria is a risk factor in coronary heart disease. All patients admitted with acute myocardial infarction in 1996 were included. At baseline, we recorded urinary albumin/creatinine concentration ratio, body mass index, blood pressure, left ventricle ejection fraction by echocardiography, smoking status, medication, diabetes, age, and gender. Deaths were traced in 2007 by means of the Danish Personal Identification Register. Microalbuminuria, defined as a urinary albumin/creatinine concentration ratio above 0.65 mg/mmoL, occurred in 50% of the patients and was associated with increased all-cause mortality. Thus, 68% of the patients with microalbuminuria versus 48% of the patients without microalbuminuria had died during the 10 years of follow-up (P=0.04. The crude hazard ratio for death associated with microalbuminuria was 1.78 (CI: 1.18-2.68 (P=0.006, whereas the gender- and age-adjusted hazard ratio was 1.71 (CI: 1.03-2.83 (P=0.04. We concluded that microalbuminuria in hospitalized patients with acute myocardial infarction is prognostic for increased long-term mortality. We recommend measurement of microalbuminuria to be included as a baseline risk factor in patients with acute myocardial infarction and in future trials in patients with cor-onary heart disease.

  14. Ten-year viability study on natural populations of Drosophila sibling species from Laguna Verde, Veracruz, México.

    Science.gov (United States)

    Pimentel, E; Cruces, M P; Salceda, V M; de la Rosa, M E; Levine, L; Castillo, J A

    2004-02-01

    The generation of electricity in nuclear power plants produces an increase in background radiation that could possibly have some impact on the organisms that live in that area. In order to identify and quantify any such possible effect, the natural populations of two sibling species, D. melanogaster and D. simulans, that live in the immediate vicinity of the first Mexican Nuclear Power Plant were analyzed for a period of 10 years. Collections of flies were made at two sites, one close to and one farther from the power plant, during the pre and operational stages of the reactor, and their egg-to-adult viability was analyzed. The data obtained indicate that in both sites, the egg-to-adult viability was generally higher in D. melanogaster than in D. simulans. Further, a relationship was found between egg-to-adult viability and the season of the year (warm-wet or cool-dry season). Some differences were found between the two sites. It may be concluded that there is no negative impact on the Drosophila populations studied. PMID:15106671

  15. Chernobyl - ten years after

    International Nuclear Information System (INIS)

    This folder contains ten brief factsheets which aim to give a balanced presentation of the facts relating to the reactor accident at the Chernobyl power station ten years after the event. Details of the incident are given and its aftermath, in particular as it has affected the lives and health of people living in the immediate vicinity, is considered. Since records of the health of people in the region before the accident were very poor, it is extremely difficult to make definitive statements about the health effects of the accident. It is clear, however, that there has been a marked increase in the incidence of thyroid cancer especially among children in Belarus. Although curable this has given rise to deaths owing to poor health care. It is likely that deaths due to other cancers will occur in the longer term. Though estimates vary, they are in the region of 10-25,000 world wide over the next 70 years. Comparisons with the numbers of deaths from other large-scale non-nuclear industrial disasters are provided which put the Chernobyl incident in context and experts who refute the wilder claims made in the media are quoted. The status of the plant today and the international effort to improve the safety of the 15 original RMBK commercial reactors still operating in the former USSR are described. (Author)

  16. Demystifying Instructional Innovation: The Case of Teaching with Case Studies

    Science.gov (United States)

    Kantar, Lina D.

    2013-01-01

    Issues emerging from instructional innovation are inevitable, yet basing any curriculum shift on a theoretical framework is paramount. This paper grounds the case-based pedagogy in three learning theories: behaviorism, cognitivism, and constructivism. The three theories are described and situated in relation to the case study method. An…

  17. Feet swelling in a multistage ultraendurance triathlete: a case study

    Science.gov (United States)

    Knechtle, Beat; Zingg, Matthias Alexander; Knechtle, Patrizia; Rosemann, Thomas; Rüst, Christoph Alexander

    2015-01-01

    Recent studies investigating ultraendurance athletes showed an association between excessive fluid intake and swelling of the lower limbs such as the feet. To date, this association has been investigated in single-stage ultraendurance races, but not in multistage ultraendurance races. In this case study, we investigated a potential association between fluid intake and feet swelling in a multistage ultraendurance race such as a Deca Iron ultratriathlon with ten Ironman triathlons within 10 consecutive days. A 49-year-old well-experienced ultratriathlete competed in autumn 2013 in the Deca Iron ultratriathlon held in Lonata del Garda, Italy, and finished the race as winner within 129:33 hours:minutes. Changes in body mass (including body fat and lean body mass), foot volume, total body water, and laboratory measurements were assessed. Food and fluid intake during rest and competing were recorded, and energy and fluid turnovers were estimated. During the ten stages, the volume of the feet increased, percentage body fat decreased, creatinine and urea levels increased, hematocrit and hemoglobin values decreased, and plasma [Na+] remained unchanged. The increase in foot volume was significantly and positively related to fluid intake during the stages. The poststage volume of the foot was related to poststage total body water, poststage creatinine, and poststage urea. This case report shows that the volume of the foot increased during the ten stages, and the increase in volume was significantly and positively related to fluid intake during the stages. Furthermore, the poststage volume of the foot was related to poststage total body water, poststage creatinine, and poststage urea. The continuous feet swelling during the race was most probably due to a combination of a high fluid intake and a progressive decline in renal function (ie, continuous increase in creatinine and urea), leading to body fluid retention (ie, increase in total body water). PMID:26508884

  18. A Qualitative Case Study Illustrating the Benefits of Discussion Roles in Online Asynchronous Discussion

    Science.gov (United States)

    Hancock, Cheryl J.

    2012-01-01

    This research describes a qualitative, naturalistic case study of a situation-specific, in-depth exploration of the use of ten student discussion roles in and adult education, online asynchronous discussions. Discussion roles were designed in order to enable students to respond better and create deeper and more meaning-filled threaded discussions,…

  19. Using Narrative Case Studies in an Online World Religions Course to Stimulate Deep Learning about Islam

    Science.gov (United States)

    Elliott, Sherman Lee

    2010-01-01

    The purpose of this action research was to examine how a narrative case study in an online asynchronous world religions course affected learners' understandings, appreciation, and respect for the beliefs and values of others. The world religions course examined a variety of religions including Islam. Ten participants received information about the…

  20. A Qualitative Case Study Illustrating the Benefits of Discussion Roles in Online Asynchronous Discussion

    Science.gov (United States)

    Hancock, Cheryl J.

    2012-01-01

    This research describes a qualitative, naturalistic case study of a situation-specific, in-depth exploration of the use of ten student discussion roles in and adult education, online asynchronous discussions. Discussion roles were designed in order to enable students to respond better and create deeper and more meaning-filled threaded discussions,…

  1. How Do Faculty Make Formative Use of Student Evaluation Feedback? A Multiple Case Study

    Science.gov (United States)

    Yao, Yuankun; Grady, Marilyn L.

    2005-01-01

    This multiple case study explored faculty formative use of student evaluation feedback. Results were based on interviews of ten education faculty members at a midwestern research university and reviews of relevant documents. It was found that end of semester student evaluation, originally used for summative evaluation, was also used by faculty for…

  2. A study on heparin in complex with L1 protein of ten high risk Human Papillomavirus: new structural insights based on in silico analysis

    Directory of Open Access Journals (Sweden)

    Jorge Félix Beltrán Lissabet

    2015-01-01

    Full Text Available Human papillomavirus (HPV is one of the most common causes of sexually transmitted diseases in both men and women around the world. It has been suggested that the heparan sulfate constitute the main receptor recognized by HPV, however its role during the interactions with other HPV is not very clear. BC, DE, EF, FG, and HI are the five loops displayed on the surface of the pentamer which can interact with heparin as an analogue for heparan sulfate. In this study, the L1 late protein of ten high risks HPV (HR HPV L1 corresponding to the types 31/33/35/39/45/51/52/56/58/59 were analyzed using in silico methods by looking for insights related to HR HPV L1-loops and heparin interactions. The five loop regions (BC, DE, EF, FG and HI of the ten HR HPV L1 interact with heparin, where the interaction established between the BC-loop and heparin was found to be present in all the HR HPV L1 analyzed in this study as well as those reported in the scientist literature. Moreover it was found that lysine residues are involves in most of interactions and that the chargecharge and polar interactions are stabilizing the HR HPV L1-heparin interaction. The results obtained in this work with all the in silico methods; suggest that the heparin-binding site in the loops for all the HR HPV plays an important role during HR HPV infections, where BC-loop constitute the most required structure during the HR HPV L1-heparin interactions. The charge-charge and polar interactions are the main forces stabilizing the HR HPV L1-heparin.

  3. Enhancing Tourism Competitiveness of Hong Kong via Tourism Planning: A Comparative Case Study between Hong Kong and Singapore

    OpenAIRE

    Kaewta Muangasame; Siyathorn Khunon

    2013-01-01

    This article aims to recommend tourism planning in Hong Kong (HK). A comparison case study of tourism planning between Singapore and Hong Kong is discussed. Secondary data from web sites, observations and in-depth interviews of ten residents and ten tourists was conducted to investigate tourism planning in the two countries. The study discloses that the HK government should consider adopting a long term oriented plan and implement an integrated approach with their tourism planning. Sustainabi...

  4. The case for case studies: Optimising the use of communication cases

    Directory of Open Access Journals (Sweden)

    Tony Jaques

    2009-01-01

    Full Text Available Case studies are widely used by communication and public relations practitioners and educators. Yet, despite their extensive use, the question should be asked whether public relations case studies are applied in the best possible way. Many tertiary education institutions are moving away from case study analysis as a discrete subject and instead adopting a ‘case study approach’ across the communication curriculum. This paper explores the merits of different styles of the case method and the reference materials available, and concludes that formalised analysis of case studies is essential to fully optimise their application.

  5. Theoretical pluralism in psychoanalytic case studies

    OpenAIRE

    Willemsen, Jochem; Cornelis, Shana; Geerardyn, Filip M.; Desmet, Mattias; Meganck, Reitske; Inslegers, Ruth; Cauwe, Joachim M. B. D.

    2015-01-01

    The aim of this study is to provide an overview of the scientific activity of different psychoanalytic schools of thought in terms of the content and production of case studies published on ISI Web of Knowledge. Between March 2013 and November 2013, we contacted all case study authors included in the online archive of psychoanalytic and psychodynamic case studies (www.singlecasearchive.com) to inquire about their psychoanalytic orientation during their work with the patient. The response rate...

  6. Roadmaster Roading Contractors Case Study

    Directory of Open Access Journals (Sweden)

    Hazel Taylor

    1999-01-01

    Full Text Available Systems analysis students seldom experience the practical difficulties of the initial investigation into a client’s requirements. They get little chance to practice the skills they need to investigate complex and confused problem situations, or to appreciate the wider organizational issues that can impact on a situation. This teaching case is designed to give students the opportunity to practice and apply investigation skills and to challenge them to consider the wider work environment when considering possible solutions to a problem situation. The case is conducted as a role-play, with students acting as systems analysts and teaching staff role-playing the clients. The students develop a report analyzing the client’s situation based on the issues that arise during the interviews. Feed-back sessions focus on discussing how well the students applied various interviewing strategies previously covered in lectures, and on the wider organizational problems that could impact proposed information system solutions.

  7. Hemofiltración continua en pacientes con complicaciones abdominales del síndrome hemolítico urémico: Report of ten cases Continuous hemofiltration in children with abdominal complications of hemolytic uremic syndrome

    Directory of Open Access Journals (Sweden)

    Felipe Cavagnaro SM

    2002-07-01

    Full Text Available Background: Close to one half of patients with hemolytic uremic syndrome (HUS will require a dialytic therapy, mainly peritoneal dialysis (PD. In some cases, PD may have relative or absolute contraindications, usually when HUS is associated to severe intra-abdominal complications. Aim: To report the results of continuous hemofiltration use, in children with abdominal complications of HUS. Material and methods: Retrospective review of the files of 40 patients that were admitted to our pediatric unit with HUS, since 1995. Six children had relevant intra-abdominal complications and were treated with continuous hemofiltration (CHF. Four additional children, with similar HUS related complications and treated with CHF before 1995, were included in the analysis. Results: The age of the patients ranged from 5 to 66 months old. An arterio-venous CHF was performed in four and veno-venous CHF in six children. The duration of CHF was 93.2 hours in average. Adequate control of volemia was achieved in every patient; diafiltration with peritoneal dialysis solution was added in five patients, to improve azotemia. Four patients had complications related to the vascular access or the anticoagulation procedure. The procedure was terminated due to improvement of diuresis in five cases, transfer to PD in four and a cardiorespiratory arrest in one. Only one patient developed a chronic renal failure during the follow up. Conclusions: CHF is an effective and safe alternative of acute renal replacement therapy in the management of renal failure in pediatric cases with HUS, aggravated with abdominal complications (Rev Méd Chile 2002; 130: 768-72.

  8. L’utilisation du TENS en physiothérapie : la situation particulière des soins palliatifs oncologiques

    OpenAIRE

    Laliberté, Maude; Dyer, Joseph-omer

    2012-01-01

    Trans-cutaneous electrical nerve stimulation (TENS) is a treatment against pain that uses the application of an electric current. Some studies suggest that TENS would reduce the pain associated with certain types of cancer and this treatment is regularly used in therapy in contexts of interdisciplinary practice specializing in palliative oncology. However, the use of TENS in cancer cases is a matter of controversy, and its application is contraindicated by Canadian standards governing the pra...

  9. Study on Case Teaching of Financial Management

    OpenAIRE

    Zhenghong Che; Zhengmei Che

    2011-01-01

    Case teaching is an efficient teaching method of management. It plays an important role to enhance the students’ ability to practice the theory. However, case teaching of financial management has not achieved the expected results. The paper aims to study the importance, characteristics and corresponding methods of case teaching method of financial management.

  10. Study on Case Teaching of Financial Management

    Science.gov (United States)

    Che, Zhenghong; Che, Zhengmei

    2011-01-01

    Case teaching is an efficient teaching method of management. It plays an important role to enhance the students' ability to practice the theory. However, case teaching of financial management has not achieved the expected results. The paper aims to study the importance, characteristics and corresponding methods of case teaching method of financial…

  11. The ten thousand Kims

    International Nuclear Information System (INIS)

    In Korean culture, the names of family members are recorded in special family books. This makes it possible to follow the distribution of Korean family names far back in history. It is shown here that these name distributions are well described by a simple null model, the random group formation (RGF) model. This model makes it possible to predict how the name distributions change and these predictions are shown to be borne out. In particular, the RGF model predicts that for married women entering a collection of family books in a certain year, the occurrence of the most common family name 'Kim' should be directly proportional to the total number of married women with the same proportionality constant for all the years. This prediction is also borne out to a high degree. We speculate that it reflects some inherent social stability in the Korean culture. In addition, we obtain an estimate of the total population of the Korean culture down to the year 500 AD, based on the RGF model, and find about ten thousand Kims.

  12. Occupation and lung cancer in Shanghai: a case-control study.

    OpenAIRE

    Levin, L. I.; Zheng, W.; Blot, W. J.; Gao, Y.T.; Fraumeni, J. F.

    1988-01-01

    Occupation was evaluated as a potential risk factor for lung cancer as part of a large population based case-control study conducted in the ten urban districts of Shanghai. A total of 733 newly diagnosed cases of male lung cancer and 760 controls selected from the general population was interviewed to obtain lifetime occupational histories and information on smoking and other factors. Of the approximately 25 major industrial titles examined, significantly raised risks, adjusted for smoking, w...

  13. Geothermal Exploration Case Studies on OpenEI (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Young, K.; Bennett, M.; Atkins, D.

    2014-03-01

    The U.S. Geological Survey (USGS) resource assessment (Williams et al., 2008) outlined a mean 30 GWe of undiscovered hydrothermal resource in the western United States. One goal of the U.S. Department of Energy's (DOE) Geothermal Technology Office (GTO) is to accelerate the development of this undiscovered resource. DOE has focused efforts on helping industry identify hidden geothermal resources to increase geothermal capacity in the near term. Increased exploration activity will produce more prospects, more discoveries, and more readily developable resources. Detailed exploration case studies akin to those found in oil and gas (e.g. Beaumont and Foster, 1990-1992) will give developers central location for information gives models for identifying new geothermal areas, and guide efficient exploration and development of these areas. To support this effort, the National Renewable Energy Laboratory (NREL) has been working with GTO to develop a template for geothermal case studies on the Geothermal Gateway on OpenEI. In 2012, the template was developed and tested with two case studies: Raft River Geothermal Area (http://en.openei.org/wiki/Raft_River_Geothermal_Area) and Coso Geothermal Area (http://en.openei.org/wiki/Coso_Geothermal_Area). In 2013, ten additional case studies were completed, and Semantic MediaWiki features were developed to allow for more data and the direct citations of these data. These case studies are now in the process of external peer review. In 2014, NREL is working with universities and industry partners to populate additional case studies on OpenEI. The goal is to provide a large enough data set to start conducting analyses of exploration programs to identify correlations between successful exploration plans for areas with similar geologic occurrence models.

  14. Integrating case-control and TDT studies.

    OpenAIRE

    Kazeem, GR; Farrall, M

    2005-01-01

    Genetic-association studies are widely expected to unravel the genetic basis of complex diseases. The population-based case-control study, a commonly used approach for association studies, is subject to the problem of population admixture. Consequently, evidence of disease-marker associations obtained from such studies is ideally confirmed by alternative methods. The Transmission/Disequilibrium Test (TDT) is suitable to assess evidence of association obtained from case-control studies. Since ...

  15. Leishmaniasis in dogs: Case study

    Directory of Open Access Journals (Sweden)

    Aleksi? Jelena

    2009-01-01

    Full Text Available The paper presents a case of leishmaniasis in a 2.5-month-old dog imported from France. The clinical examination established a generally poor state of health, expressed cachexia, atrophy of the temporal musculature, weakness of movement, as well as abnormally long and brittle nails. There was also hyperkeratosis of the nose tip and paws. A histological examination of biopsy sections of the altered skin parts showed inflammatory changes in the area of the dermis, together with infiltration of macrophages and a smaller number of lymphocytes, plasmocytes and neutrophil granulocytes in the area around the sebaceous glands and hair follicles. The determined changes correspond to superficial dermatitis. Edema followed by partial degeneration of connective-tissue fibers is observed in connective tissue. A smaller number of intracellular parasitic forms was established in mononuclear cells. A smaller number of oval amastigotes with round dark red nucleis were observed in sections stained using the Gimza method in the cytoplasm of macrophages located in the dermis, but also extracellularly. It was concluded that the dog was diseased with leishmaniasis on the grounds of the clinical picture and the microscopic findings.

  16. Use of 3D-computed tomography angiography for planning the surgical removal of pineal region meningiomas using Poppen's approach: a report of ten cases and a literature review

    Directory of Open Access Journals (Sweden)

    Li Ye

    2011-06-01

    Full Text Available Abstract Background There are several treatment approaches for pineal region meningiomas, such as Poppen's approach, Krause's approach and combinations of the two approaches. We present our experience with the use of 3D-computed tomography angiography for planning the surgical removal of pineal region meningiomas using a suboccipital transtentorial approach (Poppen's approach and evaluate the role of Poppen's approach. Methods During the period from January 2005 to June 2010, ten patients presented to us with pineal region meningioma. MRI was routinely used to define the tumor size, position, and its relevant complications while 3D-CTA was applied to define the blood supply of the tumor and the venous complex (VC shift before operations. Most of the meningiomas had developed at both sides of the tentorial plane and extended laterally with typical characteristics of a pineal region tumor. Results All tumors were completely removed surgically without any injury to the VC. Postoperative intracranial infection occurred in one case who recovered after antibiotics were given. Postoperative intraventricular hemorrhage and pneumocephalus were found in one case, but fully recovered after conservative treatment. In the nine cases of concurrent hydrocephalus, this was gradually relieved in eight patients and the single case that became aggravated was successfully treated with ventriculoperitoneal shunt. Moreover, the follow-up MRI examinations did not indicate any recurrence of the meningiomas. Conclusion We found that the use of Poppen's approach is strongly supported for the successful removal of pineal region meningiomas without serious complications.

  17. Ten steps or climbing a mountain: A study of Australian health professionals' perceptions of implementing the baby friendly health initiative to protect, promote and support breastfeeding

    Directory of Open Access Journals (Sweden)

    Sheehan Athena

    2011-08-01

    Full Text Available Abstract Background The Baby Friendly Hospital (Health Initiative (BFHI is a global initiative aimed at protecting, promoting and supporting breastfeeding and is based on the ten steps to successful breastfeeding. Worldwide, over 20,000 health facilities have attained BFHI accreditation but only 77 Australian hospitals (approximately 23% have received accreditation. Few studies have investigated the factors that facilitate or hinder implementation of BFHI but it is acknowledged this is a major undertaking requiring strategic planning and change management throughout an institution. This paper examines the perceptions of BFHI held by midwives and nurses working in one Area Health Service in NSW, Australia. Methods The study used an interpretive, qualitative approach. A total of 132 health professionals, working across four maternity units, two neonatal intensive care units and related community services, participated in 10 focus groups. Data were analysed using thematic analysis. Results Three main themes were identified: 'Belief and Commitment'; 'Interpreting BFHI' and 'Climbing a Mountain'. Participants considered the BFHI implementation a high priority; an essential set of practices that would have positive benefits for babies and mothers both locally and globally as well as for health professionals. It was considered achievable but would take commitment and hard work to overcome the numerous challenges including a number of organisational constraints. There were, however, differing interpretations of what was required to attain BFHI accreditation with the potential that misinterpretation could hinder implementation. A model described by Greenhalgh and colleagues on adoption of innovation is drawn on to interpret the findings. Conclusion Despite strong support for BFHI, the principles of this global strategy are interpreted differently by health professionals and further education and accurate information is required. It may be that the current processes used to disseminate and implement BFHI need to be reviewed. The findings suggest that there is a contradiction between the broad philosophical stance and best practice approach of this global strategy and the tendency for health professionals to focus on the ten steps as a set of tasks or a checklist to be accomplished. The perceived procedural approach to implementation may be contributing to lower rates of breastfeeding continuation.

  18. Simultaneous determination of ten compounds in rat plasma by UPLC-MS/MS: Application in the pharmacokinetic study of Ma-Zi-Ren-Wan.

    Science.gov (United States)

    Hu, Dong-Dong; Han, Quan-Bin; Zhong, Linda Li-Dan; Li, Yan-Hong; Lin, Cheng-Yuan; Ho, Hing-Man; Zhang, Man; Lin, Shu-Hai; Zhao, Ling; Huang, Tao; Mi, Hong; Tan, Hong-Sheng; Xu, Hong-Xi; Bian, Zhao-Xiang

    2015-09-01

    Ma-Zi-Ren-Wan (MZRW) is a classic Chinese formula which has been used to treat human constipation in China for over 2000 years. In order to make good and rational use of this formula in the future, this paper presents the first attempt to track the pharmacokinetic features of MZRW in rat using rapid and sensitive ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). Ten chemical components of MZRW, namely, rhein, emodin, aloe emodin, hesperidin, naringin, amygdalin, albiflorin, paeoniflorin, magnolol and honokiol, were simultaneously determined in rat plasma after a single oral administration (10g/kg body weight) of MZRW to rats. Geniposide and liquiritin were used as internal standards. The separation was performed on a Waters ACQUITY BEH C18 column (100mm×2.1mm, 1.7?m). The detection was conducted by multiple-reaction monitoring (MRM) in negative ionization mode. Two highest abundant MRM transitions without interference were optimized for each analyte. This method was well validated in terms of linearity, precision, accuracy, recovery, matrix effect and stability. All calibration curves had good linearity (r(2)>0.995) over the concentration range from 3.9 to 125.0ng/mL for emodin, 3.9-500.0ng/mL for amygdalin, 2.0-4000.0ng/mL for naringin and hesperidin, 3.9-2000.0ng/mL for magnolol, 7.8-2000.0ng/mL for rhein and 3.9-4000.0ng/mL for albiflorin, paeoniflorin, aloe emodin and honokiol. The intra-day and inter-day precision (relative standard deviation) was within 15%, the accuracy (relative error) ranged from -13.6% to 15.1%, and the lower limit of quantification in plasma ranged between 2.0ng/mL and 7.8ng/mL. Extraction recovery, matrix effect and stability were satisfactory. The validated method was successfully applied to a pharmacokinetic study of these ten compounds after oral administration of MZRW to rats. The pharmacokinetic parameters of each compound can facilitate clinical studies in the future. PMID:26231677

  19. Embedded nursing practice: a case study.

    Science.gov (United States)

    Bott, M

    1997-01-01

    Nurses' utilization of case study analysis often focuses on medically-based knowledge which is intertwined within our daily practice. Reflection on nurse-patient interactions with nursing theory as the analytic tool is infrequently undertaken. The case study analysis presented within this paper analyzes an exemplar utilizing the theoretical works of Patricia Benner. PMID:9460362

  20. Using Case Studies: An International Approach

    Science.gov (United States)

    McClam, Tricia; Woodside, Marianne

    2005-01-01

    Case studies as an instructional strategy have been used in many disciplines, including law, teacher education, science, medicine, and business. Among the benefits of this method of instruction are involving students in learning, developing their critical thinking skills, promoting communication, and engaging in critical analysis. Case studies are…

  1. Erythema nodosum: prospective study of 32 cases.

    Science.gov (United States)

    Fernandes, N C; Maceira, J; Muniz, M de M

    1994-01-01

    The results of 32 cases studied lead us to the conclusion that erythema nodosum's investigation routine is very important, once in our retrospective study, the percentage of cases of unknown etiology was 69.4%, and in this prospective study it is 21.8%. In 10 cases (31.2%), more than one causing agent was suspected. Infections (bacterial, helminthic, fungal, by protozoa) were diagnosed in 26 cases, streptococcal infection having predominated (12 cases). Drugs-dipirone, aspirin, anovulatory--were suspected as causing agents in 13 cases. The association of erythema nodosum and histoplasmosis capsulata is described for the first time in Brazil. We consider erythema nodosum to be a complex syndrome which should be regarded as a manifestation of underlying diseases. The fact that all 32 subjects were women, 26 of them during menacme, suggests that particular hormonal media may favor the action of various processes (infections and drugs), precipitating erythema nodosum's clinical picture. PMID:7569624

  2. BOOK REVIEW: Case Studies in Knowledge Management

    Directory of Open Access Journals (Sweden)

    Reviewed by Dr. Adnan BOYACI

    2005-10-01

    Full Text Available 161Case Studies in Knowledge ManagementEdited by Murray JennexHersley: PA: Idea Group, 2005, pp. 372, ISBN 1-59140-352-9Reviewed by Dr. Adnan BOYACIAnadolu UniversityEskişehir-TurkeyKnowledge management (KM as a structured system and the way to the effectiveness isrelatively new field for the contemporary organizations functioning in different andcompetitive domain of public and private sectors in terms of getting optimal effectivenessunderlined by the concepts such as quality, productivity…etc. Because of the growingimportance and the popularity of the KM either as a research topic or specialized coursesubject, a crucial need for understanding, conceptualization and implementation of KM asa system has emerged since the mid 1990’s. In this sense, the book contributes criticallyto fill the gap between theory and implementation as a teaching material.This edited book is published by Idea Group Publishing. The book has twenty chaptersdivided into seven sections. In addition to a section of authors’ biography contributing thebook and an index, there is a preface that the basic terms and key concepts underliningthe cases discussed following chapters, which is explained in a schematized way.Besides the editor, total of 47 authors have contributed to the book. These authors arefrom different countries, academic backgrounds, and institutions. Although approximatelyone third of the authors are from USA, the rest of the authors are from Canada, England,Austria, Germany, Australia, New Zealand, Egypt, Bahrain and China. The authorsrepresent a variety of universities, private companies, and military institutions. Most ofthem have strong professional backgrounds, which help them address the issues bothfrom theoretical and practical perspectives. Contributions of authors having differentbackgrounds and institutions enable the book to have very comprehensive spectrum andthis makes the book attractive practically for those working different sectors.The book presents case studies explaining actual applications of KM in a different oforganizational and global settings. Different subjects and issues associated withconstruction of KM system in different kinds of organizations are explored within eachsection. Organizational learning (OL, knowledge, culture and productivity are some ofthe issues tackled with construction of KM system in a variety of organizational andglobal settings.The book is organized into seven sections; KM in support of organizational learning,knowledge management in support of retaining organizational knowledge, knowledgemanagement strategy, issues in knowledge management, KM is support of knowledgetransfer, KM in support of projects, KM outcomes. Each section is related with an area KMresearch.In section I, there are two cases discussing KM in support of OL. The first case is fromLynne P. Cooper, Rebecca L. Nash, Tu-Anh T. Phan, and Teresa R. Bailey and describesdevelopment and operation of knowledge system in order to support learning oforganizational knowledge at the Jet Propulsion Laboratory in USA. It presents in detailimplementation and rollout of the system and argues the results from performance andusage data collected over 19 weeks. The second case is from Brigette McGregor-MacDonald and describes the work of global organizations in its KM efforts to sustain andtransfer learning from global leadership curriculum. It mainly focuses on KM solution162developed to support employees to sustain their learning, to enable them to share theirinsights and experiences with others, and thus increase organizational capability.Section 2 explores using KM to support the retention of organizational knowledge inorganizations where the work forces are in transition. In third chapter in this section HaniAbdel-Aziz, and Khaled Wahba discuss the building of organizational memory informationsystem (OMIS in an Egyptian Professional Services company suffering from knowledgeloss due to high rate of employee turnover In the fourth chapter, Gail Corbitt discussesdefinition identification and the transfer of the core competencies associated with thesplit to all employees who need to have them when HP splits into HP and AgilentSection three explores the importance of a KM strategy in the implementation of a KMinitiative. In chapter five, Afsoun Hatami and Robert D. Galliers discuss long term impactsof knowledge (re use and organizational memory on effectiveness of strategic decisions.Suzanne Zyngier, Frada Burstein, and Judy McKay, in chapter six discusses governancestrategies to manage organizational knowledge in Australia’s Science and TechnologyDevelopment Organization. In chapter seven, Summer E. Bartczak and Ellen C. Englanddiscuss the issues and challenges in developing KM strategy for the United States’ AirForce Material Command’s.In section four, the use of KM in the support of projects and project management arediscussed. Elayne Coakes, Anton Bradburn, and Cathy Blake, in chapter eight discuss thetopic ‘KM in a projects-t climate’. Under this topic, they mainly focus on using of KM tominimize mischance by promoting best practices in the British construction firm TaylorWoodrow In chapter nine, Jill Owen and Frada Burstein look at where knowledge residesin an Australian consulting firm and how the firm uses this knowledge to improve projectperformance. This case study highlights the importance of understanding the drivers ofknowledge transfer and reuse in the projects.In section five KM in support of knowledge transfer is explored and discussed. Zhang Li,Tian Yezhuang, and Li Ping, in chapter ten, focus on the effect of knowledge sharing inthe process of enterprise resource planning (ERP system implementation in a Chinesemanufacturing firm. Thomas Hahn, Bernhard Schmiedinger, and Elisabeth Stephan, inchapter eleven, discuss the use of communities of practice and other techniques toimprove the transfer of knowledge in and between Austrian small and medium sizedmanufacturing firms. In chapter twelve, Florian Bayer, Rafael Enparantza, Ronald Maier,Franz Obermair, and Bernhard Schmiedinger discuss the use of Know Com to facilitate thedecentralized control of the flow of knowledge between small and medium sized Germandie and mould makers.In section six, different issues and problems associated with the implementation of KMand a knowledge management system (KMS are discussed. In chapter thirteen, YogeshAnand, David J. Pauleen, and Sally Dexter look at adoption and implementation of KM inthe New Zealand Reserve Bank. Colin White and David Crosdell, in chapter fourteen, lookat the assessment methods for organizing data and data resources in organizations byfocusing on four cases and provide examples for organizations based on ability to activelycollect and distribute knowledge.In chapter fifteen, Minwir Al-Shammari, discussesdeveloping an understanding of the various aspects and issues related with theimplementation of a knowledge enabled customer relationship management (KCRMstrategy at a telecommunication company in a developing country. Ivy Chan and PatrickY.K. Chau, in chapter sixteen, explore why a KM failed in a Hong Kong manufacturing andexport firm. In chapter seventeen, Nikhil Mehta and Anju Mehta look at theimplementation efforts of one such firm-India’s Infosys Technologies, Limited and discusshow KM emerged as a strategic requirement of the firm, and various capabilities the firmhad to develop to fulfill this requirement. Eliot Rich and Peter Duchessi, at the lastchapter–chapter eighteen – of this section, explores how to manage KM initiative going163after it has been successful for a couple of years at the United States’ SystemManagement Solutions International.Section 7 discusses the determination of KM outcomes. A.N. Dwivedi, Rajeev K. Bali, andR.N.G. Naguib, in chapter nineteen, explore a general KM framework for the Britishhealthcare industry and how to manage KM successfully. In chapter twenty, Murray E.Jennex looks at how the use of knowledge can impact individual and organizationalproductivity.

  3. Five case studies of multifamily weatherization programs

    Energy Technology Data Exchange (ETDEWEB)

    Kinney, L; Wilson, T.; Lewis, G. [Synertech Systems Corp. (United States); MacDonald, M. [Oak Ridge National Lab., TN (United States)

    1997-12-31

    The multifamily case studies that are the subject of this report were conducted to provide a better understanding of the approach taken by program operators in weatherizing large buildings. Because of significant variations in building construction and energy systems across the country, five states were selected based on their high level of multifamily weatherization. This report summarizes findings from case studies conducted by multifamily weatherization operations in five cities. The case studies were conducted between January and November 1994. Each of the case studies involved extensive interviews with the staff of weatherization subgrantees conducting multifamily weatherization, the inspection of 4 to 12 buildings weatherized between 1991 and 1993, and the analysis of savings and costs. The case studies focused on innovative techniques which appear to work well.

  4. Theoretical pluralism in psychoanalytic case studies.

    Science.gov (United States)

    Willemsen, Jochem; Cornelis, Shana; Geerardyn, Filip M; Desmet, Mattias; Meganck, Reitske; Inslegers, Ruth; Cauwe, Joachim M B D

    2015-01-01

    The aim of this study is to provide an overview of the scientific activity of different psychoanalytic schools of thought in terms of the content and production of case studies published on ISI Web of Knowledge. Between March 2013 and November 2013, we contacted all case study authors included in the online archive of psychoanalytic and psychodynamic case studies (www.singlecasearchive.com) to inquire about their psychoanalytic orientation during their work with the patient. The response rate for this study was 45%. It appears that the two oldest psychoanalytic schools, Object-relations psychoanalysis and Ego psychology or "Classical psychoanalysis" dominate the literature of published case studies. However, most authors stated that they feel attached to two or more psychoanalytic schools of thought. This confirms that the theoretical pluralism in psychoanalysis stretches to the field of single case studies. The single case studies of each psychoanalytic school are described separately in terms of methodology, patient, therapist, or treatment features. We conclude that published case studies features are fairly similar across different psychoanalytic schools. The results of this study are not representative of all psychoanalytic schools, as some do not publish their work in ISI ranked journals. PMID:26483725

  5. Theoretical pluralism in psychoanalytic case studies

    Science.gov (United States)

    Willemsen, Jochem; Cornelis, Shana; Geerardyn, Filip M.; Desmet, Mattias; Meganck, Reitske; Inslegers, Ruth; Cauwe, Joachim M. B. D.

    2015-01-01

    The aim of this study is to provide an overview of the scientific activity of different psychoanalytic schools of thought in terms of the content and production of case studies published on ISI Web of Knowledge. Between March 2013 and November 2013, we contacted all case study authors included in the online archive of psychoanalytic and psychodynamic case studies (www.singlecasearchive.com) to inquire about their psychoanalytic orientation during their work with the patient. The response rate for this study was 45%. It appears that the two oldest psychoanalytic schools, Object-relations psychoanalysis and Ego psychology or “Classical psychoanalysis” dominate the literature of published case studies. However, most authors stated that they feel attached to two or more psychoanalytic schools of thought. This confirms that the theoretical pluralism in psychoanalysis stretches to the field of single case studies. The single case studies of each psychoanalytic school are described separately in terms of methodology, patient, therapist, or treatment features. We conclude that published case studies features are fairly similar across different psychoanalytic schools. The results of this study are not representative of all psychoanalytic schools, as some do not publish their work in ISI ranked journals. PMID:26483725

  6. Outage management: A case study

    International Nuclear Information System (INIS)

    Outage management issues identified from a field study conducted at a two-unit commercial pressurized water reactor (PWR), when one unit was in a refueling outage and the other unit was at full power operation, are the focus of this paper. The study was conduced as part of the US Nuclear Regulatory Commission's (NRC) organizational factors research program, and therefore the issues to be addressed are from an organizational perspective. Topics discussed refer to areas identified by the NRC as critical for safety during shutdown operations, including outage planning and control, personnel stress, and improvements in training and procedures. Specifically, issues in communication, management attention, involvement and oversight, administrative processes, organizational culture, and human resources relevant to each of the areas are highlighted by example from field data collection. Insights regarding future guidance in these areas are presented based upon additional data collection subsequent to the original study

  7. Hemangioma racemoso de retina (síndrome de Wyburn-Mason): acompanhamento de um paciente por dez anos: relato de caso / Retinal racemose hemangioma (Wyburn-Mason syndrome): a patient ten years follow-up: case report

    Scientific Electronic Library Online (English)

    RL, Leitão Guerra; CL, Leitão Guerra; M, Guerra; AS, Guerra Neto; AA, Leitão Guerra.

    2009-08-01

    Full Text Available Relatar o caso de um paciente que apresentou hemangioma racemoso de retina (síndrome de Wyburn-Mason) e seu acompanhamento por 10 anos. Dez anos após o diagnóstico da doença o exame oftalmológico não sofreu alterações, assim como o campo visual e a retinografia. O prognóstico a longo prazo é controv [...] erso. Alguns autores relatam estabilidade das lesões oculares, como no caso descrito, enquanto outros referem perda progressiva da visão. Abstract in english To describe the case of a patient who presents retinal racemose hemangioma (Wyburn-Mason syndrome) and his 10 years follow-up. Ten years after the disease diagnosis, the ophthalmologic exam had no changes, as well as the campimetry and the retinography. The long term prognosis is controversial. Some [...] authors report ocular lesions stability and others report progressive visual loss.

  8. Ten Famous Double Stars

    Science.gov (United States)

    Argyle, Bob; Argyle, R. W.

    In this chapter we move out from the Sun and look at some of the neighbouring double and multiple stars which have been observed for centuries. In some cases there are still secrets to be revealed. The beauty of a sunset on Earth has inspired poets and artists for millennia—what must it be like when there is not one sunset but two or more with each sun glowing in a different color. The chiaroscuro would be impressive to say the least. Not all double and multiple systems have different colors—some contain stars of essentially the same spectral class and therefore color (Table 9.1).

  9. INTERIORITY - a prefab case study

    DEFF Research Database (Denmark)

    Hvejsel, Marie Frier

    Dealing with the general theme of domestic architectural quality, the PhD thesis ‘INTERIORITY’ takes its point of departure in the continuous and increasing need to improve our capability as architects to theoretically articulate the intangible concept of quality, and to reveal it through an active...... been motivated by the particular hypothesis that an introduction of the notion of interiority, as an ability of the spatial envelope itself to address the sensuous scale of furniture, unfolds a particular dual critical potential signifying our experience of domestic architectural quality: On the one......, tectonically. Hence, it has been a particular idea of the study to explore the relation between furniture, the spatial envelope itself, and its construct by using furniture as an architectural concept. Consequently, the thesis has specifically investigated whether this notion of interiority, describing an...

  10. A network security case study

    International Nuclear Information System (INIS)

    This paper reports on a study to validate the Graphical Network Representation (GRPHREP) model which is being conducted on the Los Alamos National Laboratory Integrated Computer Network (ICN). The GRPHREP model is a software system application based on graph theory and object-oriented programming methodologies. It codified the Department of Energy (DOE) Order 5637.1, which is concerned with classified computer secret policy, restrictions, and requirements. The Los Alamos ICN is required to control access to and support large-scale scientific and administrative computing. Thus, large-scale scientific and administrative computing. Thus we felt that this large, complex, and dynamic network would provide a good test for the graphical and functional capabilities of the model. Furthermore, the ICN is composed of multiple partitions that reflect the sensitivity and classification of the computation (data) and designate the required clearance level for the user

  11. Case study on printed matter

    DEFF Research Database (Denmark)

    Introduction Existing product Life Cycle Assessments (LCA’s) on offset printed matter all point at paper as the overall dominating contributor to the impacts from the life-cycle of this category of products. This dominating role of paper is primarily founded in the energy-related impact categorie......-person-equivalents-targeted, mPET). The avoided energy consumptions and emissions due to incineration and recycling of paper are allocated to “Paper (net)”....... in recycled materials like paper is not included in this study. Taking these issues into account will most probably increase the importance of the chemical related impact categories in the life cycle of printed matter. References Larsen HF, Hansen MS, Hauschild M (2009). Life-cycle assessment of...

  12. Case Study: A Strategic Research Methodology

    Directory of Open Access Journals (Sweden)

    Khairul B.M. Noor

    2008-01-01

    Full Text Available This research reviews the literature on case study as a strategic qualitative research methodology. Although case studies have been criticised by some authors as lacking scientific rigour and do not address generalizability, this research, however, reiterated its appropriateness when dealing with a process or a complex real-life activities in great-depth. Case study has been commonly used in social science fields like sociology, industrial relations and anthropology eventhough generally was considered an underutilized strategy. Hence, this research explained the general concept of a case study, strengths and weaknesses of using this method knowing that theoretically case is exciting and data rich. Based on a study of four organizations and the researcher?s own experience, this article described matters on how case study was undertaken, gaining excess to those organizations and the systematic process of data collection and triangulation (multiple techniques. It was noted that combining multiple techniques for elicitng data in case study research actually strengthens and confirmed results.

  13. Antiphospholipid syndrome: A case study

    International Nuclear Information System (INIS)

    Full text: A forty-two-year-old male presented to the Royal Adelaide Hospital with symptoms of increasing shortness of breath, swelling in both ankles, petechial rash and blood in his sputum. Initial investigations showed cardiomegaly, right ventricular hypertrophy, patchy lung infiltrates, a platelet count of 1500 and a clotting time of 60 seconds. A V/Q scan indicated a high probability of pulmonary embolism. Further investigations showed that the patient was positive for lupus anticoagulant and cardiolipin antibodies. A diagnosis of primary antiphospholipid syndrome was made. The patient''s high risk of strokes and hemorrhaging prompted investigation by a 99mTc-HMPAO brain scan. Further V/Q scans were performed to follow up the initial finding of multiple pulmonary embolism and a R-L shunt study was performed to investigate a left subclavian murmur. The patient was admitted for four weeks and began treatment which included cyclaphosphamide, corticosteroids and plasmaphoresis and was discharged when stable. Over the next six months he was re admitted three times for relapse of antiphospholipid syndrome. On his fourth admission he collapsed and died five hours after admission. Cause of death was due to cardiac arrhythmia secondary to severe right ventricular hypertrophy and dilation. The effects of antiphospholipid syndrome was believed to be responsible for this outcome

  14. Antiphospholipid syndrome: A case study

    Energy Technology Data Exchange (ETDEWEB)

    Davies, T. [Royal Adelaide Hospital, Adelaide, SA (Australia). Department of Nuclear Medicine

    1998-03-01

    Full text: A forty-two-year-old male presented to the Royal Adelaide Hospital with symptoms of increasing shortness of breath, swelling in both ankles, petechial rash and blood in his sputum. Initial investigations showed cardiomegaly, right ventricular hypertrophy, patchy lung infiltrates, a platelet count of 1500 and a clotting time of 60 seconds. A V/Q scan indicated a high probability of pulmonary embolism. Further investigations showed that the patient was positive for lupus anticoagulant and cardiolipin antibodies. A diagnosis of primary antiphospholipid syndrome was made. The patient``s high risk of strokes and hemorrhaging prompted investigation by a {sup 99}mTc-HMPAO brain scan. Further V/Q scans were performed to follow up the initial finding of multiple pulmonary embolism and a R-L shunt study was performed to investigate a left subclavian murmur. The patient was admitted for four weeks and began treatment which included cyclaphosphamide, corticosteroids and plasmaphoresis and was discharged when stable. Over the next six months he was re admitted three times for relapse of antiphospholipid syndrome. On his fourth admission he collapsed and died five hours after admission. Cause of death was due to cardiac arrhythmia secondary to severe right ventricular hypertrophy and dilation. The effects of antiphospholipid syndrome was believed to be responsible for this outcome.

  15. Case Study Report about Gender Impact Assessment

    DEFF Research Database (Denmark)

    Faber, Stine Thidemann; Agustin, Lise Rolandsen

    2013-01-01

    The aim of this national case study report is to take a closer look at the use of Gender Impact Assessments in Denmark in order to describe the Danish implementation of this specific Gender Mainstreaming method. By way of analyzing two selected cases (two law proposals put forward by The Danish...

  16. Case studies of steel structure failures

    Directory of Open Access Journals (Sweden)

    P. Bernasovský

    2010-01-01

    Full Text Available The contribution deals with some case studies of steel structure failures, which happened in Slovakia a few years ago. Features of cracking are illustrated on real cases of breakdowns in the transmission gas pipelines, at the cement works and in the petrochemical indus-try. All failures were caused by an incorrect technical approach. Possible remedial measures are proposed.

  17. Does present use of cardiovascular medication reflect elevated cardiovascular risk scores estimated ten years ago? A population based longitudinal observational study

    Directory of Open Access Journals (Sweden)

    Straand Jørund

    2011-03-01

    Full Text Available Abstract Background It is desirable that those at highest risk of cardiovascular disease should have priority for preventive measures, eg. treatment with prescription drugs to modify their risk. We wanted to investigate to what extent present use of cardiovascular medication (CVM correlates with cardiovascular risk estimated by three different risk scores (Framingham, SCORE and NORRISK ten years ago. Methods Prospective logitudinal observational study of 20 252 participants in The Hordaland Health Study born 1950-57, not using CVM in 1997-99. Prescription data obtained from The Norwegian Prescription Database in 2008. Results 26% of men and 22% of women aged 51-58 years had started to use some CVM during the previous decade. As a group, persons using CVM scored significantly higher on the risk algorithms Framingham, SCORE and NORRISK compared to those not treated. 16-20% of men and 20-22% of women with risk scores below the high-risk thresholds for the three risk scores were treated with CVM, while 60-65% of men and 25-45% of women with scores above the high-risk thresholds received no treatment. Among women using CVM, only 2.2% (NORRISK, 4.4% (SCORE and 14.5% (Framingham had risk scores above the high-risk values. Low education, poor self-reported general health, muscular pains, mental distress (in females only and a family history of premature cardiovascular disease correlated with use of CVM. Elevated blood pressure was the single factor most strongly predictive of CVM treatment. Conclusion Prescription of CVM to middle-aged individuals by large seems to occur independently of estimated total cardiovascular risk, and this applies especially to females.

  18. Why is seed production so variable among individuals? A ten-year study with oaks reveals the importance of soil environment.

    Science.gov (United States)

    Pérez-Ramos, Ignacio M; Aponte, Cristina; García, Luis V; Padilla-Díaz, Carmen M; Marañón, Teodoro

    2014-01-01

    Mast-seeding species exhibit not only a large inter-annual variability in seed production but also considerable variability among individuals within the same year. However, very little is known about the causes and consequences for population dynamics of this potentially large between-individual variability. Here, we quantified seed production over ten consecutive years in two Mediterranean oak species - the deciduous Quercus canariensis and the evergreen Q. suber - that coexist in forests of southern Spain. First, we calibrated likelihood models to identify which abiotic and biotic variables best explain the magnitude (hereafter seed productivity) and temporal variation of seed production at the individual level (hereafter CVi), and infer whether reproductive effort results from the available soil resources for the plant or is primarily determined by selectively favoured strategies. Second, we explored the contribution of between-individual variability in seed production as a potential mechanism of satiation for predispersal seed predators. We found that Q. canariensis trees inhabiting moister and more fertile soils were more productive than those growing in more resource-limited sites. Regarding temporal variation, individuals of the two studied oak species inhabiting these resource-rich environments also exhibited larger values of CVi. Interestingly, we detected a satiating effect on granivorous insects at the tree level in Q. suber, which was evident in those years where between-individual variability in acorn production was higher. These findings suggest that individual seed production (both in terms of seed productivity and inter-annual variability) is strongly dependent on soil resource heterogeneity (at least for one of the two studied oak species) with potential repercussions for recruitment and population dynamics. However, other external factors (such as soil heterogeneity in pathogen abundance) or certain inherent characteristics of the tree might be also involved in this process. PMID:25532130

  19. Ten cases of Actinobaculum schaalii infection

    DEFF Research Database (Denmark)

    Reinhard, Mark; Prag, Jørgen; Kemp, Michael; Andresen, Keld; Klemmensen, Belinda; Højlyng, Niels; Sørensen, Susan Hildebrand; Christensen, Jens Jørgen

    2005-01-01

    Nine of 10 strains of Actinobaculum schaalii caused urinary tract infections in predisposed individuals. Identification included 16S rRNA gene sequence analysis and use of the API Coryne and Rapid ID 32 A test systems. A. schaalii is easily overlooked due to its slow growth in ambient air and its...... resemblance to the normal bacterial flora on skin and mucosa....

  20. Ten Challenges for Decision Neuroscience

    Directory of Open Access Journals (Sweden)

    ScottAHuettel

    2010-09-01

    Full Text Available Decision neuroscience research, as currently practiced, employs the methods of neuroscience to investigate concepts drawn from the social sciences. A typical study selects one or more variables from psychological or economic models, manipulates or measures choices within a simplified choice task, and then identifies neural correlates. Using this “neuroeconomic” approach, researchers have described brain systems whose functioning shapes key economic variables, most notably aspects of subjective value. Yet, the standard approach has fundamental limitations. Important aspects of the mechanisms of decision making – from the sources of variability in decision making to the very computations supported by decision-related regions – remain incompletely understood. Here, I outline ten outstanding challenges for future research in decision neuroscience. While some will be readily addressed using current methods, others will require new conceptual frameworks. Accordingly, a new strain of decision neuroscience will marry methods from economics and cognitive science to concepts from neurobiology and cognitive neuroscience.

  1. Feet swelling in a multistage ultraendurance triathlete: a case study

    Directory of Open Access Journals (Sweden)

    Knechtle B

    2015-10-01

    Full Text Available Beat Knechtle,1 Matthias Alexander Zingg,2 Patrizia Knechtle,1 Thomas Rosemann,2 Christoph Alexander Rüst2 1Gesundheitszentrum St Gallen, St Gallen, 2Institute of Primary Care, University of Zurich, Zurich, Switzerland Abstract: Recent studies investigating ultraendurance athletes showed an association between excessive fluid intake and swelling of the lower limbs such as the feet. To date, this association has been investigated in single-stage ultraendurance races, but not in multistage ultraendurance races. In this case study, we investigated a potential association between fluid intake and feet swelling in a multistage ultraendurance race such as a Deca Iron ultratriathlon with ten Ironman triathlons within 10 consecutive days. A 49-year-old well-experienced ultratriathlete competed in autumn 2013 in the Deca Iron ultratriathlon held in Lonata del Garda, Italy, and finished the race as winner within 129:33 hours:minutes. Changes in body mass (including body fat and lean body mass, foot volume, total body water, and laboratory measurements were assessed. Food and fluid intake during rest and competing were recorded, and energy and fluid turnovers were estimated. During the ten stages, the volume of the feet increased, percentage body fat decreased, creatinine and urea levels increased, hematocrit and hemoglobin values decreased, and plasma [Na+] remained unchanged. The increase in foot volume was significantly and positively related to fluid intake during the stages. The poststage volume of the foot was related to poststage total body water, poststage creatinine, and poststage urea. This case report shows that the volume of the foot increased during the ten stages, and the increase in volume was significantly and positively related to fluid intake during the stages. Furthermore, the poststage volume of the foot was related to poststage total body water, poststage creatinine, and poststage urea. The continuous feet swelling during the race was most probably due to a combination of a high fluid intake and a progressive decline in renal function (ie, continuous increase in creatinine and urea, leading to body fluid retention (ie, increase in total body water. Keywords: swimming, cycling, running, fluid

  2. BTS Case Study: The Galloway Family Home

    International Nuclear Information System (INIS)

    Case study of an energy-efficient Habitat for Humanity house that uses 30% less energy than conventional residential construction. The project was part of the Jimmy Carter Work Project in rural Appalachia in 1997

  3. Towards More Case Study Research in Entrepreneurship

    Directory of Open Access Journals (Sweden)

    Tom Duxbury

    2012-03-01

    Full Text Available Entrepreneurship as an emerging discipline has made good strides, but according to some, has fallen short of bringing its theory and literature up to the standards of others in the management sciences. Rich with the descriptive detail needed for insightful theory building in entrepreneurship, scholars have called for more case study research, particularly those incorporating non-retrospective and longitudinal observations. At the same time however, it has become rare to find such research published in A-level journals dedicated to entrepreneurship. A survey presented here of major entrepreneurship journals over the past six years revealed a publication rate of only 3% using the case study method. This presents a major impediment for developing fresh research in this field based upon the study of real cases. The author explores how the case study method has been applied to entrepreneurship research and provides recommendations for improved publication rates.

  4. Ten Commandments of System Conversions.

    Science.gov (United States)

    Chabotar, Kent John

    1998-01-01

    Administrators at Bowdoin College (Maine) have translated lessons learned from the process of administrative software conversion into ten commandments for other small colleges undertaking such changes. Three approaches to management information systems are outlined, with advantages and limitations highlighted, as well as the ten recommendations,…

  5. Eccrine Angiomatous Hamartoma: A Retrospective Study of 15 Cases

    Directory of Open Access Journals (Sweden)

    Yi-Ting Lin

    2012-04-01

    Full Text Available Background: Eccrine angiomatous hamartoma (EAH comprises a rare nevoid proliferation of normal eccrine glands and small blood vessels and occasionally otherelements in the middle and deep dermis with variable clinical manifestations.Case series have rarely been published except for case reports and literaturereviews. The aims of this article were to investigate the clinical and pathologic features of patients with EAH in Taiwan and to compare our resultswith the results of previous studies.Methods: A retrospective review of medical records and histopathological findings wasperformed on patients diagnosed with EAH in a medical center in Taiwanbetween 1994 and 2010.Results: Fifteen patients with pathologically diagnosed EAH were collected. Themean age at the time of diagnosis was 38.6 years (range, birth to 67 years.The male to female ratio was 3 to 2. In most cases, EAH arose as a singlelesion on a lower extremity. The symptoms and signs most commonly associated with EAH were pain (60%, hypertrichosis (13.3%, itching (13.3%and hyperhidrosis (6.7%. Additional pathological findings included hemangioma (13.3%, verrucous hemangioma (6.7%, arteriovenous malformation(6.7%, and angiokeratoma (6.7%. None of the patients experienced spontaneous regression of the lesions before excision. Excisions were done in onepatient under general anesthesia, and ten patients with local anesthesia. Fourpatients were kept under observation. Tumor recurrences were noted in twoout of the eleven patients whose lesions were excised.Conclusion: Compared with cases in the literature, we found additional histopathologicalfindings and an increased tumor recurrence risk in our cohort. EAH remainsa benign and uncommon hamartomatous condition. Further multi-center, retrospective studies with larger case numbers are needed to better characterizethe disease presentation in Asian populations.

  6. Predicting Students Drop Out: A Case Study

    Science.gov (United States)

    Dekker, Gerben W.; Pechenizkiy, Mykola; Vleeshouwers, Jan M.

    2009-01-01

    The monitoring and support of university freshmen is considered very important at many educational institutions. In this paper we describe the results of the educational data mining case study aimed at predicting the Electrical Engineering (EE) students drop out after the first semester of their studies or even before they enter the study program…

  7. Participative Case Studies: Integrating Case Writing and a Traditional Case Study Approach in a Marketing Context

    Science.gov (United States)

    Forman, Howard

    2006-01-01

    Case-based pedagogy is a valuable tool for applying business concepts and theories to organizational contexts. Traditional case-based pedagogy offers such learning opportunities. What this pedagogy lacks, however, is an element of real-time experiential learning opportunities. This research focuses on the advantages of incorporating a case-writing…

  8. Ground-source heat pump case studies and utility programs

    Energy Technology Data Exchange (ETDEWEB)

    Lienau, P.J.; Boyd, T.L.; Rogers, R.L.

    1995-04-01

    Ground-source heat pump systems are one of the promising new energy technologies that has shown rapid increase in usage over the past ten years in the United States. These systems offer substantial benefits to consumers and utilities in energy (kWh) and demand (kW) savings. The purpose of this study was to determine what existing monitored data was available mainly from electric utilities on heat pump performance, energy savings and demand reduction for residential, school and commercial building applications. In order to verify the performance, information was collected for 253 case studies from mainly utilities throughout the United States. The case studies were compiled into a database. The database was organized into general information, system information, ground system information, system performance, and additional information. Information was developed on the status of demand-side management of ground-source heat pump programs for about 60 electric utility and rural electric cooperatives on marketing, incentive programs, barriers to market penetration, number units installed in service area, and benefits.

  9. Frequency and antimicrobial resistance patterns of bacteria implicated in community urinary tract infections: a ten-year surveillance study (2000–2009)

    Science.gov (United States)

    2013-01-01

    Background Urinary tract infection (UTI) is one of the most common infectious diseases at the community level. In order to assess the adequacy of the empirical therapy, the prevalence and the resistance pattern of the main bacteria responsible for UTI in the community (in Aveiro, Portugal) was evaluated throughout a ten-year period. Methods In this retrospective study, all urine samples from patients of the District of Aveiro, in ambulatory regime, collected at the Clinical Analysis Laboratory Avelab during the period 2000–2009 were analysed. Samples with more than 105 CFU/mL bacteria were considered positive and, for these samples, the bacteria were identified and the profile of antibiotic susceptibility was characterized. Results From the 155597 samples analysed, 18797 (12.1%) were positive for bacterial infection. UTI was more frequent in women (78.5%) and its incidence varied with age, affecting more the elderly patients (38.6%). Although E. coli was, as usual, the most common pathogen implicated in UTI, it were observed differences related to the other bacteria more implicated in UTI relatively to previous studies. The bacteria implicated in the UTI varied with the sex of the patient, being P. aeruginosa a more important cause of infection in men than in women. The incidence of the main bacteria changed over the study period (P. aeruginosa, Klebsiella spp and Providencia spp increased and Enterobacter spp decreased). Although E. coli was responsible for more than an half of UTI, its resistance to antibiotics was low when compared with other pathogens implicated in UTI, showing also the lowest percentage of multidrug resistant (MDR) isolates (17%). Bacteria isolated from females were less resistant than those isolated from males and this difference increased with the patient age. Conclusions The differences in sex and age must be taken into account at the moment of empirical prescription of antimicrobials. From the recommended antimicrobials by the European Association of Urology guidelines, the first line drugs (pivmecillinam and nitrofurantoin) and the alternative antibiotic amoxicillin-clavulanic acid (AMX-CLA) are appropriate to treat community-acquired UTI, but the fluoroquinolones should not be suitable to treat male infections and the trimethoprim-sulfamethoxazole (SXT) shall not be used in the treatment of UTI at this level. PMID:23327474

  10. Frequency and antimicrobial resistance patterns of bacteria implicated in community urinary tract infections: a ten-year surveillance study (2000–2009

    Directory of Open Access Journals (Sweden)

    Linhares Inês

    2013-01-01

    Full Text Available Abstract Background Urinary tract infection (UTI is one of the most common infectious diseases at the community level. In order to assess the adequacy of the empirical therapy, the prevalence and the resistance pattern of the main bacteria responsible for UTI in the community (in Aveiro, Portugal was evaluated throughout a ten-year period. Methods In this retrospective study, all urine samples from patients of the District of Aveiro, in ambulatory regime, collected at the Clinical Analysis Laboratory Avelab during the period 2000–2009 were analysed. Samples with more than 105 CFU/mL bacteria were considered positive and, for these samples, the bacteria were identified and the profile of antibiotic susceptibility was characterized. Results From the 155597 samples analysed, 18797 (12.1% were positive for bacterial infection. UTI was more frequent in women (78.5% and its incidence varied with age, affecting more the elderly patients (38.6%. Although E. coli was, as usual, the most common pathogen implicated in UTI, it were observed differences related to the other bacteria more implicated in UTI relatively to previous studies. The bacteria implicated in the UTI varied with the sex of the patient, being P. aeruginosa a more important cause of infection in men than in women. The incidence of the main bacteria changed over the study period (P. aeruginosa, Klebsiella spp and Providencia spp increased and Enterobacter spp decreased. Although E. coli was responsible for more than an half of UTI, its resistance to antibiotics was low when compared with other pathogens implicated in UTI, showing also the lowest percentage of multidrug resistant (MDR isolates (17%. Bacteria isolated from females were less resistant than those isolated from males and this difference increased with the patient age. Conclusions The differences in sex and age must be taken into account at the moment of empirical prescription of antimicrobials. From the recommended antimicrobials by the European Association of Urology guidelines, the first line drugs (pivmecillinam and nitrofurantoin and the alternative antibiotic amoxicillin-clavulanic acid (AMX-CLA are appropriate to treat community-acquired UTI, but the fluoroquinolones should not be suitable to treat male infections and the trimethoprim-sulfamethoxazole (SXT shall not be used in the treatment of UTI at this level.

  11. Dez anos de experiência com cirurgia micrográfica pelo método de Munique: relato de 93 casos operados / A ten-year experience with the Munich method of micrographic surgery: a report of 93 operated cases

    Scientific Electronic Library Online (English)

    Luis Fernando Figueiredo, Kopke; Patricia Salomé, Gouvêa; Jose Caldeira Ferreira, Bastos.

    2005-12-01

    Full Text Available FUNDAMENTOS: A cirurgia de Mohs é um dos métodos mais eficazes de tratamento dos carcinomas basocelulares. A expansão de seus conceitos possibilitou o surgimento de outros métodos de checagem de margens cirúrgicas igualmente eficazes. O método de Munique é um exemplo disso. OBJETIVOS: Avaliar a efic [...] ácia da cirurgia micrográfica pelo método de Munique em um estudo de coorte com 10 anos de duração. MÉTODOS: 93 pacientes com 96 tumores cutâneos foram tratados com cirurgia micrográfica pelo método de Munique, participando de um protocolo de acompanhamento, no período de maio de 1994 a julho de 2004. RESULTADOS: 61,4% dos tumores eram recidivados; 42,3% eram recidivados mais de uma vez; 53% eram do tipo esclerodermiforme. A média do maior diâmetro dos tumores foi de 1,58cm e do menor 1,10cm. Em 95% dos casos se obteve a extirpação total do tumor, com até três estágios. A localização mais comum foi a nasal (46,3%), seguida da periocular (18,9%) e da frontal (11,5%). Perdeu-se o contato apenas com dois pacientes. Dos 96 tumores operados, apenas 11 têm tempo de seguimento inferior a dois anos. 56 pacientes foram seguidos por pelo menos cinco anos, e 45 (47,3%), por mais de seis anos. Apenas um caso de recidiva foi verificado, tendo ocorrido no sexto ano de observação. CONCLUSÃO: O método de Munique é um método eficiente de cirurgia micrográfica, tanto quanto o método de Mohs. Este trabalho fornece mais um indício de que o conceito de cirurgia micrográfica deve ser ampliado para cirurgia microscopicamente controlada, e não ficar ligado estritamente ao termo cirurgia de Mohs. Abstract in english BACKGROUND: Mohs surgery is one of the most effective treatments for basal cell carcinomas. The expansion of its concepts enabled developing other equally effective methods to check surgical margins, and the Munich method is an example. OBJECTIVES: To evaluate the effectiveness of the Munich method [...] of micrographic surgery in a ten-year cohort study. METHODS: Ninety-three patients with a total of 96 skin tumors were treated with the Munich method of micrographic surgery, taking part in a follow-up protocol, from May 1994 through July 2004. RESULTS: Of all tumors, 61.4% were recurrent, 42.3% were recurrent more than once, and 53% were of the sclerodermiform type. The mean larger diameter was 1.58cm, and the mean smaller diameter was 1.10cm. In 95% of the cases, total extirpation of the tumor was obtained in three stages. The most common site was nasal (46.3%), followed by periocular (18.9%) and frontal (11.5%). Two patients were lost in follow-up. Of the 96 operated tumors, only 11 had a follow-up time shorter than 2 years. Fifty-six patients were followed for at least 5 years, and 45 (47.3%) for over 6 years. A single relapse was observed, which took place in the sixth year of observation. CONCLUSION: The Munich method is an efficient method of micrographic surgery, as good as the Mohs method. This study provides further evidence that the concept of micrographic surgery must be broadened to surgical excision with microscopic margin control, rather than linking it exclusively to the term "Mohs micrographic surgery".

  12. Dez anos de experiência com cirurgia micrográfica pelo método de Munique: relato de 93 casos operados A ten-year experience with the Munich method of micrographic surgery: a report of 93 operated cases

    Directory of Open Access Journals (Sweden)

    Luis Fernando Figueiredo Kopke

    2005-12-01

    Full Text Available FUNDAMENTOS: A cirurgia de Mohs é um dos métodos mais eficazes de tratamento dos carcinomas basocelulares. A expansão de seus conceitos possibilitou o surgimento de outros métodos de checagem de margens cirúrgicas igualmente eficazes. O método de Munique é um exemplo disso. OBJETIVOS: Avaliar a eficácia da cirurgia micrográfica pelo método de Munique em um estudo de coorte com 10 anos de duração. MÉTODOS: 93 pacientes com 96 tumores cutâneos foram tratados com cirurgia micrográfica pelo método de Munique, participando de um protocolo de acompanhamento, no período de maio de 1994 a julho de 2004. RESULTADOS: 61,4% dos tumores eram recidivados; 42,3% eram recidivados mais de uma vez; 53% eram do tipo esclerodermiforme. A média do maior diâmetro dos tumores foi de 1,58cm e do menor 1,10cm. Em 95% dos casos se obteve a extirpação total do tumor, com até três estágios. A localização mais comum foi a nasal (46,3%, seguida da periocular (18,9% e da frontal (11,5%. Perdeu-se o contato apenas com dois pacientes. Dos 96 tumores operados, apenas 11 têm tempo de seguimento inferior a dois anos. 56 pacientes foram seguidos por pelo menos cinco anos, e 45 (47,3%, por mais de seis anos. Apenas um caso de recidiva foi verificado, tendo ocorrido no sexto ano de observação. CONCLUSÃO: O método de Munique é um método eficiente de cirurgia micrográfica, tanto quanto o método de Mohs. Este trabalho fornece mais um indício de que o conceito de cirurgia micrográfica deve ser ampliado para cirurgia microscopicamente controlada, e não ficar ligado estritamente ao termo cirurgia de Mohs.BACKGROUND: Mohs surgery is one of the most effective treatments for basal cell carcinomas. The expansion of its concepts enabled developing other equally effective methods to check surgical margins, and the Munich method is an example. OBJECTIVES: To evaluate the effectiveness of the Munich method of micrographic surgery in a ten-year cohort study. METHODS: Ninety-three patients with a total of 96 skin tumors were treated with the Munich method of micrographic surgery, taking part in a follow-up protocol, from May 1994 through July 2004. RESULTS: Of all tumors, 61.4% were recurrent, 42.3% were recurrent more than once, and 53% were of the sclerodermiform type. The mean larger diameter was 1.58cm, and the mean smaller diameter was 1.10cm. In 95% of the cases, total extirpation of the tumor was obtained in three stages. The most common site was nasal (46.3%, followed by periocular (18.9% and frontal (11.5%. Two patients were lost in follow-up. Of the 96 operated tumors, only 11 had a follow-up time shorter than 2 years. Fifty-six patients were followed for at least 5 years, and 45 (47.3% for over 6 years. A single relapse was observed, which took place in the sixth year of observation. CONCLUSION: The Munich method is an efficient method of micrographic surgery, as good as the Mohs method. This study provides further evidence that the concept of micrographic surgery must be broadened to surgical excision with microscopic margin control, rather than linking it exclusively to the term "Mohs micrographic surgery".

  13. Ten shades of black

    CERN Document Server

    Hod, Shahar

    2015-01-01

    The holographic principle has taught us that, as far as their entropy content is concerned, black holes in $(3+1)$-dimensional curved spacetimes behave as ordinary thermodynamic systems in flat $(2+1)$-dimensional spacetimes. In this essay we point out that the opposite behavior can also be observed in black-hole physics. To show this we study the quantum Hawking evaporation of near-extremal Reissner-Nordstr\\"om black holes. We first point out that the black-hole radiation spectrum departs from the familiar radiation spectrum of genuine $(3+1)$-dimensional perfect black-body emitters. In particular, the would be black-body thermal spectrum is distorted by the curvature potential which surrounds the black hole and effectively blocks the emission of low-energy quanta. Taking into account the energy-dependent gray-body factors which quantify the imprint of passage of the emitted radiation quanta through the black-hole curvature potential, we reveal that the $(3+1)$-dimensional black holes effectively behave as p...

  14. Case Study Report about Gender Impact Assessment

    DEFF Research Database (Denmark)

    Faber, Stine Thidemann; Agustin, Lise Rolandsen

    2013-01-01

    The aim of this national case study report is to take a closer look at the use of Gender Impact Assessments in Denmark in order to describe the Danish implementation of this specific Gender Mainstreaming method. By way of analyzing two selected cases (two law proposals put forward by The Danish Ministry of Employment and the Danish Ministry of Transport, respectively) the aim is to assess the transformative potential of GIA as it is performed in Denmark.

  15. Management by Values: A Case Study

    OpenAIRE

    Liu, Zhen

    2012-01-01

    The intention of this paper is to conclude the management approach by the case study of Chinese enterprise. There are a lot of management approaches in practice, one of the most influential and famous one is management by objective which is invented by the father of modern management discipline Peter F Drucker, he observed the case of American most successful enterprise such as GM and then concluded and created the relevant meaningful management tools, in effect, such valuable manage...

  16. L’utilisation du TENS en physiothérapie : la situation particulière des soins palliatifs oncologiques

    Directory of Open Access Journals (Sweden)

    Laliberté, Maude

    2012-11-01

    Full Text Available Trans-cutaneous electrical nerve stimulation (TENS is a treatment against pain that uses the application of an electric current. Some studies suggest that TENS would reduce the pain associated with certain types of cancer and this treatment is regularly used in therapy in contexts of interdisciplinary practice specializing in palliative oncology. However, the use of TENS in cancer cases is a matter of controversy, and its application is contraindicated by Canadian standards governing the practice of physiotherapy. This article aims to present, through a case study, some principles to guide decision making regarding the choice of this therapy in cases of cancer. Scientific evidence, standards of practice and ethical principles that should guide the choice of therapy are discussed. The use of TENS therapy in palliative care is a paradigmatic example of a common situation: the weighing by health care professionals of the benefits and potential costs, such as potential adverse effects of treatment. In the case of TENS, the benefits are associated with the reduction of pain, while a potential adverse effect would increase tumour proliferation. This difficult calculation has implications for the various stakeholders such as patients and health professionals.

  17. Clean Cities Case Study: Barwood Cab Fleet Study Summary

    International Nuclear Information System (INIS)

    Barwood Cab Fleet Study Summary is the second in a new series called''Alternative Fuel Information Case Studies,'' designed to present real-world experiences with alternative fuels to fleet managers and other industry stakeholders

  18. The afterglows of whole school development in Ghana: a case study of semi-rural municipality

    OpenAIRE

    Ghartey, Seth Baisie.

    2011-01-01

    It is nearly ten years ago when Whole School Development (WSD) in Ghana was officially ended. Yet, most of its structures, systems and practices continue to function in the country. This thesis is based on data collected from a case study of a semi-rural municipality of the country regarding the reasons for its official ending and why despite its official ending, most of the structures, systems and practices continue to function. The thesis also indicates which of the structures, systems and ...

  19. Epidemiological Study of RRT-Treated ESRD in Nanjing - A Ten-Year Experience in Nearly Three Million Insurance Covered Population

    OpenAIRE

    Han, Yu-chen; Huang, Han-Ming; Sun, Ling; Tan, Chao-Ming; Gao, Min; Liu, Hong; Tang, Ri-ning; Wang, Yan-Li; WANG, BEI; Ma, Kun-Ling; Liu, Bi-Cheng

    2016-01-01

    Background The growing burden of end-stage renal disease (ESRD) has been a great challenge to the health care system of China. However, the exact epidemiological data for ESRD in China remain unclear. We aimed to investigate the epidemiology of ESRD treated by renal replacement therapy (RRT) in Nanjing based on analysing ten-year data of Nanjing three million insurance covered population. Methods Using the electronic registry system of Urban Employee Basic Medical Insurance (UEBMI), we includ...

  20. Trends in the theoretical and research methodological approaches applied in doctoral studies in information and knowledge management: an exploration of ten years of research in South Africa

    OpenAIRE

    M. A. Mearns

    2008-01-01

    The past ten years have seen the field of information and knowledge management develop and implement new and improved technologies. Because of the ease with which information is exchanged the contribution to information overload has increased exponentially and the need for information and knowledge management is more real than ever before. Research in itself is a science of knowledge creation that continuously evolves in line with newly developed theories and research methodologies. An invest...

  1. Study of enzyme replacement therapy for Gaucher Disease: comparative analysis of clinical and laboratory parameters at diagnosis and after two, five and ten years of treatment

    OpenAIRE

    Ana Maria Almeida Souza; Thiago Pimentel Muniz; Rafael Maciel Brito

    2014-01-01

    Objective: To evaluate the impact of enzyme replacement therapy for Gaucher Disease on clinical and laboratory parameters after two, five and ten years of treatment. Methods: Data were collected from patient records and analyzed using BioEstat software (version 5.0). Student's t-test, Analysis of Variance (ANOVA), Wilcoxon test and Kruskal–Wallis test were used for statistical analysis. Hepatomegaly and splenomegaly were analyzed using the Kappa test. Results: There was a significant incr...

  2. Hereditary myeloperoxidase deficiency: study of 12 cases.

    Science.gov (United States)

    Larrocha, C; Fernández de Castro, M; Fontan, G; Viloria, A; Fernández-Chacón, J L; Jiménez, C

    1982-11-01

    12 cases of hereditary myeloperoxidase (MPO) deficiency are reported. Histochemical stainings, lysosomal enzyme determinations, electron microscopic study of MPO and granulocytic function were performed. Family studies on 2 generations were carried out in 5 patients and histochemical stainings and biochemical lysosomal enzyme determinations were done. MPO deficiency was found to follow autosomal recessive inheritance and only rarely to have clinical effects. PMID:6296995

  3. Designing data governance model - case study

    OpenAIRE

    Vänskä, Ari

    2013-01-01

    Objectives of the study The purpose of this study was to find suitable and effective method for designing data governance model. The objective is to develop data governance model by utilizing general frameworks and theories from the literature that could be applied to the empirical part of the study. Thus the goal is to build design method with frameworks and theories combined with empirical research and test this method in case context. The main motivator for the study was an o...

  4. Measuring marketing performance - A case study

    OpenAIRE

    Laakso, Vesa-Pekka

    2011-01-01

    PURPOSE OF THE STUDY The purpose of this study is to develop a marketing dashboard for a Finnish company that operates in the financial industry. The identification of suitable metrics for assessing marketing performance is considered central. This study proposes a new construct (a dashboard) that aims to providing management relevant information on marketing performance from decision-making perspective. METHODOLOGY AND DATA The methodology is a constructive case study. In the...

  5. Ten Smart Snacks for Teens

    Science.gov (United States)

    ... Program > Living With Diabetes > Youth and Teens > Ten Smart Snacks for Teens | Share External Link Disclaimer Youth and Teens Contact Us Health Information Center Phone: 1-800-860-8747 TTY: 1-866-569- ...

  6. Ten Smart Snacks for Teens

    Science.gov (United States)

    ... HealthSense Alternate Language URL Ten Smart Snacks for Teens Page Content Many adults think that snacking isn’t a healthy habit for their growing teen. The truth is that most teens need snacks; ...

  7. ABACC ten years applying safeguards

    International Nuclear Information System (INIS)

    The Argentinian-Brazilian Agency for Accounting and Control of nuclear special materials has been in operations for ten years. The rational behind the creation and the work performed by the Agency during the last decade is described. (author)

  8. Top Ten Bed Bug Tips

    Science.gov (United States)

    ... EPA United States Environmental Protection Agency Search Search Bed Bugs Share Facebook Twitter Google+ Pinterest Contact Us ... Bugs Top Ten Tips to Prevent or Control Bed Bugs Related Information Bed bugs tips (to print) ...

  9. Shuttle Case Study Collection Website Development

    Science.gov (United States)

    Ransom, Khadijah S.; Johnson, Grace K.

    2012-01-01

    As a continuation from summer 2012, the Shuttle Case Study Collection has been developed using lessons learned documented by NASA engineers, analysts, and contractors. Decades of information related to processing and launching the Space Shuttle is gathered into a single database to provide educators with an alternative means to teach real-world engineering processes. The goal is to provide additional engineering materials that enhance critical thinking, decision making, and problem solving skills. During this second phase of the project, the Shuttle Case Study Collection website was developed. Extensive HTML coding to link downloadable documents, videos, and images was required, as was training to learn NASA's Content Management System (CMS) for website design. As the final stage of the collection development, the website is designed to allow for distribution of information to the public as well as for case study report submissions from other educators online.

  10. Case study in time series analysis

    CERN Document Server

    Zhongjie, Xie

    1993-01-01

    This book is a monograph on case studies using time series analysis, which includes the main research works applied to practical projects by the author in the past 15 years. The works cover different problems in broad fields, such as: engineering, labour protection, astronomy, physiology, endocrinology, oil development, etc. The first part of this book introduces some basic knowledge of time series analysis which is necessary for the reader to understand the methods and the theory used in the procedure for solving problems. The second part is the main part of this book - case studies in differ

  11. Case studies in atomic collision physics

    CERN Document Server

    McDaniel, E W

    1974-01-01

    Case Studies in Atomic Physics III focuses on case studies on atomic and molecular physics, including atomic collisions, transport properties of electrons, ions, molecules, and photons, interaction potentials, spectroscopy, and surface phenomena. The selection first discusses detailed balancing in the time-dependent impact parameter method, as well as time-reversal in the impact parameter method and coupled state approximation. The text also examines the mechanisms of electron production in ion. Topics include measurement of doubly differential cross sections and electron spectra, direct Coul

  12. Repurposing legacy data innovative case studies

    CERN Document Server

    Berman, Jules J

    2015-01-01

    Repurposing Legacy Data: Innovative Case Studies takes a look at how data scientists have re-purposed legacy data, whether their own, or legacy data that has been donated to the public domain. Most of the data stored worldwide is legacy data-data created some time in the past, for a particular purpose, and left in obsolete formats. As with keepsakes in an attic, we retain this information thinking it may have value in the future, though we have no current use for it. The case studies in this book, from such diverse fields as cosmology, quantum physics, high-energy physics, microbiology,

  13. The comparison of grey-scale ultrasonic and clinical features of hepatoblastoma and hepatocellular carcinoma in children: a retrospective study for ten years

    Directory of Open Access Journals (Sweden)

    Luo Yan

    2011-06-01

    Full Text Available Abstract Background Hepatoblastoma (HBL and hepatocellular carcinoma (HCC are respectively the first and the second most common pediatric malignant liver tumors. The purpose of this study was to evaluate the combined use of the ultrasound examination and the assessment of the patients' clinical features for differentiating HBL from HCC in children. Methods Thirty cases of the confirmed HBL and 12 cases of the confirmed HCC in children under the age of 15 years were enrolled into our study. They were divided into the HBL group and the HCC group according to the histological types of the tumors. The ultrasonic features and the clinical manifestations of the two groups were retrospectively analyzed, with an emphasis on the following parameters: onset age, gender (male/female ratio, positive epatitis-B-surface-antigen (HBV, alpha-fetoprotein increase, and echo features including septa, calcification and liquefaction within the tumors. Results Compared with the children with HCC, the children with HBL had a significantly younger onset age (8.2 years vs. 3.9 years, P Conclusion Ultrasonic features combined with clinical manifestations are valuable for differentiating HBL from HCC in children.

  14. Corporate Social Responsibility : A Case Study

    OpenAIRE

    Björkqvist, Kira

    2012-01-01

    The importance of taking responsibility for the common environmental and social welfare has become of essence in the business world of the 21st century. This thesis provides the reader with knowledge on corporate social responsibility (CSR) and shows the reader a comparative study on how CSR is reported on in three case study companies chosen for this thesis. This thesis is a descriptive study that uses the research method of content analysis to determine the commonalities and differences...

  15. The Ten-Year History of the Asklepios Study: An Interview with Professor Ernst R. Rietzschel, Primary Investigator and Leader of the Asklepios Study.

    Science.gov (United States)

    Park, Jeong Bae

    2015-05-01

    The Asklepios study started 10 years ago when 2,500 subjects were screened between 2002 and 2004. And all of the 90+ publications we have for the moment are from those cross-sectional data. This is called round 1. Since 2011, in round 2, all of those patients have started to come back for a 10-year follow-up. At this moment, approximately 1,750 of those patients have been seen. The patients were followed by general practitioners (GP), and the GP again provided the information about what has happened with the medical status in the past 10 years including drug therapy: not only the drugs that they are taking at the moment were evaluated, but, because patients often use many drugs, the chronicles of drugs for major risk factors, for hypertension, lipids, contraceptives and more. Then, patients come to the study center where the same cluster of examinations are undertaken by one single doctor, Prof. Ernst R. Rietzschel and one study nurse, just like 10 years ago. Again, using a single observer at the two time frames has kept the methodology very strict. PMID:26587452

  16. ISOE: Ten years of experience

    International Nuclear Information System (INIS)

    The Information System on Occupational Exposure (ISOE), sponsored by the OECD Nuclear Energy Agency and the IAEA, was created in 1992 to facilitate information exchange between radiation protection experts from both operating organizations and national regulatory authorities and to enhance international co-operation on worker protection at nuclear power plants. The ISOE programme offers the world's largest database on occupational radiation exposure due to nuclear power plants covering, in 2001, 93% of the commercial power reactors in the world. In addition to providing the basis for analyses of dose trends, benchmarking and detailed studies, the ISOE also offers a system for rapid communication of radiation protection information and a forum for discussing occupational radiation exposure management issues through ISOE workshops and symposiums, organized annually. This paper is based on a report, published in 2002, summarizing the experience gained from ten years' of developing the ISOE and containing comments from participants on their experience with the system. Growing use of improved work management procedures, developed and published through the ISOE, has contributed to the downward trend in the annual average collective dose per reactor. The impact of a steam generator replacement on the evolution of this dose has also been demonstrated. To maintain or even further reduce the already low levels of occupational exposure, the ISOE needs to be regularly used and further promoted by its participants. In future, the ISOE can also play an important role in the decommissioning and dismantling of nuclear power plants. (author)

  17. Prática do abortamento entre adolescentes: um estudo em dez escolas de Maceió (AL, Brasil) / Practice of abortion among teenagers: a study in ten schools of Maceió (AL, Brazil)

    Scientific Electronic Library Online (English)

    Divanise Suruagy, Correia; Jairo Calado, Cavalcante; Eryvaldo Sócrates Tabosa do, Egito; Eulália Maria Chaves, Maia.

    2011-05-01

    Full Text Available Trata-se de um estudo de corte transversal, realizado com o objetivo de investigar as razões que levaram adolescentes a provocarem o aborto, relacionando com idade e tipo de escola que frequentavam. A amostra foi calculada considerando o número de internações para curetagem pós-abortamento. Usou-se [...] como instrumento um questionário semiestruturado, anônimo, aplicado em dez escolas, sorteadas dentre todas da cidade de Maceió (Alagoas), pesquisando-se adolescentes dos 12 aos 19 anos, do sexo feminino. Os dados foram analisados pelo Programa Epi Info, usando-se odds ratio e risco relativo para verificar associação entre variáveis e intervalo de confiança a 95%. Em uma amostra de 2.592 jovens, 559 (21,6%) tinham vida sexual ativa, 182 (7,0%) referiram ter engravidado e 149 (26,7%) abortado. Medo da reação dos pais, idade, falta de apoio do companheiro e rejeição da gravidez foram razões para provocar o aborto, sendo medo a mais citada, em ambos os tipos de escola. O aborto foi mais citado nas escolas públicas, sendo significativo e protetor o risco para abortar antes dos 15 anos, e significativa a relação entre abortar e estudar em escolas públicas. O medo da reação dos pais como razão mais frequente sugere a necessidade de novos estudos sobre sexualidade e comunicação entre pais e filhos. Abstract in english This is a cross-cut study that was carried out with the objective of investigating the causes through which adolescents have provoked abortion, relating it to age and the type of school attended. The sample was calculated by taking into account the number of hospital admissions for post-abortion cur [...] ettage. A semi-structured and anonymous questionnaire was used as a research instrument which was applied in ten schools randomly chosen among all schools, of Maceió (Alagoas, Brazil), to reach 12-19 years old female teenagers. The data were assessed by the Epi Info Program making use of odds ratio and a relative risk to verify any association among variables and a confidence interval at 95%. At a sample of 2,592 adolescents, 559 (21.6%) had an active sexual life, 182 (7.0%) informed to have been pregnant and 149 (26.7%) to have aborted. The fear of the parents' reaction, age, lack of support of the partner and pregnancy rejection were the explanation to stimulate abortion. Fear was the most mentioned cause in both types of school. Abortion was more mentioned in public schools, being significant and protective the risk of aborting before the age of 15. The fear of the parents' reaction as a frequent cause suggests the necessity for additional studies on sexuality and communication between parents and children.

  18. Prática do abortamento entre adolescentes: um estudo em dez escolas de Maceió (AL, Brasil Practice of abortion among teenagers: a study in ten schools of Maceió (AL, Brazil

    Directory of Open Access Journals (Sweden)

    Divanise Suruagy Correia

    2011-05-01

    Full Text Available Trata-se de um estudo de corte transversal, realizado com o objetivo de investigar as razões que levaram adolescentes a provocarem o aborto, relacionando com idade e tipo de escola que frequentavam. A amostra foi calculada considerando o número de internações para curetagem pós-abortamento. Usou-se como instrumento um questionário semiestruturado, anônimo, aplicado em dez escolas, sorteadas dentre todas da cidade de Maceió (Alagoas, pesquisando-se adolescentes dos 12 aos 19 anos, do sexo feminino. Os dados foram analisados pelo Programa Epi Info, usando-se odds ratio e risco relativo para verificar associação entre variáveis e intervalo de confiança a 95%. Em uma amostra de 2.592 jovens, 559 (21,6% tinham vida sexual ativa, 182 (7,0% referiram ter engravidado e 149 (26,7% abortado. Medo da reação dos pais, idade, falta de apoio do companheiro e rejeição da gravidez foram razões para provocar o aborto, sendo medo a mais citada, em ambos os tipos de escola. O aborto foi mais citado nas escolas públicas, sendo significativo e protetor o risco para abortar antes dos 15 anos, e significativa a relação entre abortar e estudar em escolas públicas. O medo da reação dos pais como razão mais frequente sugere a necessidade de novos estudos sobre sexualidade e comunicação entre pais e filhos.This is a cross-cut study that was carried out with the objective of investigating the causes through which adolescents have provoked abortion, relating it to age and the type of school attended. The sample was calculated by taking into account the number of hospital admissions for post-abortion curettage. A semi-structured and anonymous questionnaire was used as a research instrument which was applied in ten schools randomly chosen among all schools, of Maceió (Alagoas, Brazil, to reach 12-19 years old female teenagers. The data were assessed by the Epi Info Program making use of odds ratio and a relative risk to verify any association among variables and a confidence interval at 95%. At a sample of 2,592 adolescents, 559 (21.6% had an active sexual life, 182 (7.0% informed to have been pregnant and 149 (26.7% to have aborted. The fear of the parents' reaction, age, lack of support of the partner and pregnancy rejection were the explanation to stimulate abortion. Fear was the most mentioned cause in both types of school. Abortion was more mentioned in public schools, being significant and protective the risk of aborting before the age of 15. The fear of the parents' reaction as a frequent cause suggests the necessity for additional studies on sexuality and communication between parents and children.

  19. A Case Study on Collective Cognition and Operation in Team-Based Computer Game Design by Middle-School Children

    Science.gov (United States)

    Ke, Fengfeng; Im, Tami

    2014-01-01

    This case study examined team-based computer-game design efforts by children with diverse abilities to explore the nature of their collective design actions and cognitive processes. Ten teams of middle-school children, with a high percentage of minority students, participated in a 6-weeks, computer-assisted math-game-design program. Essential…

  20. A Case Study on Collective Cognition and Operation in Team-Based Computer Game Design by Middle-School Children

    Science.gov (United States)

    Ke, Fengfeng; Im, Tami

    2014-01-01

    This case study examined team-based computer-game design efforts by children with diverse abilities to explore the nature of their collective design actions and cognitive processes. Ten teams of middle-school children, with a high percentage of minority students, participated in a 6-weeks, computer-assisted math-game-design program. Essential…

  1. Study of enzyme replacement therapy for Gaucher Disease: comparative analysis of clinical and laboratory parameters at diagnosis and after two, five and ten years of treatment

    Scientific Electronic Library Online (English)

    Ana Maria Almeida, Souza; Thiago Pimentel, Muniz; Rafael Maciel, Brito.

    2014-10-01

    Full Text Available Objective: To evaluate the impact of enzyme replacement therapy for Gaucher Disease on clinical and laboratory parameters after two, five and ten years of treatment. Methods: Data were collected from patient records and analyzed using BioEstat software (version 5.0). Student's t-test, Analysis of [...] Variance (ANOVA), Wilcoxon test and Kruskal–Wallis test were used for statistical analysis. Hepatomegaly and splenomegaly were analyzed using the Kappa test. Results: There was a significant increase in hemoglobin levels (p-value

  2. ESL and Digital Video Integration: Case Studies

    Science.gov (United States)

    Li, J., Ed.; Gromik, N., Ed.; Edwards, N., Ed.

    2013-01-01

    It should come as no surprise that digital video technology is of particular interest to English language learners; students are drawn to its visual appeal and vibrant creative potential. The seven original case studies in this book demonstrate how video can be an effective and powerful tool to create fluid, fun, interactive, and collaborative…

  3. Case Studies of Altruistic Persons: AERA Roundtable.

    Science.gov (United States)

    Stephens, William N.

    This document presents information from a body of research called Lives of Service, a collection of case studies of 32 altruistic adults. It begins with a review of the research on altruism, service orientation, giving, helpfulness, social responsibility, and voluntarism. Research on altruism in psychology and in other disciplines is included,…

  4. Physics Courses--Some Suggested Case Studies

    Science.gov (United States)

    Swetman, T. P.

    1972-01-01

    To communicate the relevance and excitement of science activity to students, the use of more imaginative, and even openly speculative, case studies in physics courses is suggested. Some useful examples are Magnetic Monopoles, Constants, Black Holes, Antimatter, Zero Mass Particles, Tachyons, and the Bootstrap Hypothesis. (DF)

  5. Understanding Parkinson disease: an evolving case study.

    Science.gov (United States)

    Vernon, Gwyn M; Carty, Anne E S; Salemno, Christin M; Siskind, Michele M; Thomas, Cathi A

    2014-10-15

    Thirty years ago, Parkinson disease was described as a shortage of the neurotransmitter dopamine. Today, understanding of this disorder includes possible genetic influences, premorbid and nonmotor issues, and a variety of neurologic, cognitive, and psychiatric symptoms. Using a case study, this article presents the current science of Parkinson disease. PMID:25225972

  6. Firefighter Workplace Learning: An Exploratory Case Study

    Science.gov (United States)

    Tracey, Edward A.

    2014-01-01

    Despite there being a significant amount of research investigating workplace learning, research exploring firefighter workplace learning is almost nonexistent. The purpose of this qualitative multi-case study was to explore how firefighters conceptualize, report, and practice workplace learning. The researcher also investigated how firefighters…

  7. Climate wise case study compendium: Report 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-02-01

    This case study compendium is one of several Climate Wise tools available to help interested companies identify cost-effective options. Climate Wise, a private-public partnership program, is a key Federal initiative to return greenhouse gas emissions to 1990 levels by 2000.

  8. Three Case Studies in Green Cleaning

    Science.gov (United States)

    State Education Standard, 2012

    2012-01-01

    This article presents case studies from three districts implementing green cleaning. In 2008, Missouri passed legislation requiring state education officials to convene a committee of stakeholders with the purpose of developing green cleaning guidelines and specifications for schools. The guide, published by the Department of Elementary and…

  9. Learning Machine Learning: A Case Study

    Science.gov (United States)

    Lavesson, N.

    2010-01-01

    This correspondence reports on a case study conducted in the Master's-level Machine Learning (ML) course at Blekinge Institute of Technology, Sweden. The students participated in a self-assessment test and a diagnostic test of prerequisite subjects, and their results on these tests are correlated with their achievement of the course's learning…

  10. LCA – Unique and Controversial Case Studies

    Science.gov (United States)

    This session will focus on case studies and applications that have a unique or controversial aspect. Some of the most recent topics that seem to have significant interest include: LCA-based product declarations, LCA-based standards, LCA-based labels, alternative energy, agricul...

  11. Performance Support Case Studies from IBM.

    Science.gov (United States)

    Duke-Moran, Celia; Swope, Ginger; Morariu, Janis; deKam, Peter

    1999-01-01

    Presents two case studies that show how IBM addressed performance support solutions and electronic learning. The first developed a performance support and expert coaching solution; the second applied performance support to reducing implementation time and total cost of ownership of enterprise resource planning systems. (Author/LRW)

  12. Teaching the Holocaust through Case Study

    Science.gov (United States)

    Misco, Thomas

    2009-01-01

    This article responds to the curricular challenges teachers face with Holocaust education, including cursory treatments and a lack of focus on individual experiences. First, the author argues for a case-study approach to help students reengage concrete and complex features of the Holocaust as a point of departure for subsequent inquiry. In…

  13. WMOST v2 Case Study: Monponsett Ponds

    Science.gov (United States)

    This webinar presents an overview of the preliminary results of a case study application of EPA's Watershed Management Optimization Support Tool v2 (WMOST) for stakeholders in the Monponsett Ponds Watershed Workgroup. Monponsett Ponds is a large water system consisting of two ba...

  14. Marietta Celebration of Unity Case Study.

    Science.gov (United States)

    Philbin, Meg; Phillips, Rebecca

    This case study concerns the forming of a Marietta, Ohio unity committee, entitled Citizens for Social and Racial Justice, in response to the local Ku Klux Klan's (KKK) request for a parade permit in order to demonstrate against blacks in this city. Marietta, the county seat of Washington County, Ohio, has a population composed of both white and…

  15. The Interim Superintendent: A Case Study

    Science.gov (United States)

    Bigham, Gary; Nix, Susan J.

    2011-01-01

    Considering the vitally important role that the superintendent plays in the overall functioning and wellbeing of any school district, the filling of that position should never be done in haste. Due to the importance of this process and the time it requires, school districts often employ an interim superintendent. In this single case study, one…

  16. Firefighter Workplace Learning: An Exploratory Case Study

    Science.gov (United States)

    Tracey, Edward A.

    2014-01-01

    Despite there being a significant amount of research investigating workplace learning, research exploring firefighter workplace learning is almost nonexistent. The purpose of this qualitative multi-case study was to explore how firefighters conceptualize, report, and practice workplace learning. The researcher also investigated how firefighters…

  17. New Lives: Some Case Studies in Minamata.

    Science.gov (United States)

    Tsurumi, Kazuko

    Three case studies of young Japanese adults who fell ill with Minamata disease (a form of methyl-mercury poisoning) are presented and the adjustment of the individuals to the disease is analyzed in terms of a model of creativity. The model distinguishes three types of creativity: identificational (in which one identifies with old ideas and…

  18. Learning Machine Learning: A Case Study

    Science.gov (United States)

    Lavesson, N.

    2010-01-01

    This correspondence reports on a case study conducted in the Master's-level Machine Learning (ML) course at Blekinge Institute of Technology, Sweden. The students participated in a self-assessment test and a diagnostic test of prerequisite subjects, and their results on these tests are correlated with their achievement of the course's learning…

  19. Avio case study: the MRO process

    Science.gov (United States)

    Corallo, Angelo; Dimartino, Angelo; Errico, Fabrizio; Giangreco, Enza

    This chapter presents the case study of the Avio Brindisi plant where a profound process of change has been in progress for a number of years. We use the TEKNE Project methodology of change to analyze the different aspects of the case, highlighting the firm's strategic, organizational and technological characteristics and the environment it operates in. In particular, we envisage a change in the plant's business model in response to the expansion of its client segments and a potential new approach to MRO operations based on advanced fleet management practices that would radically change the firm's organization and value network with respect to its MRO service offering, thereby yielding extensive global market opportunities.

  20. Cook Off Study of Combustible Cartridge Cases

    Directory of Open Access Journals (Sweden)

    R.K. Syal

    1992-04-01

    Full Text Available Combustible cartridge case (CCC offers specific advantages over the conventional metallic (brass case. The CCCs are made of cellulose fibres with suitable explosives to ensure debris-free combustion inside the gun barrel. The presence of explosives in CCC, however, causes increased vulnerability to cook-off. An experimental study of cook-off of CCC was carried out by hot plate technique. Cook-off data for CCC of different compositions and with various cook-off delay coatings was measured. It was found that out of four types of coatings, two gave better results.

  1. SME business analysis. : A railway case study

    OpenAIRE

    Entezarghofran, Yashar

    2014-01-01

    The purpose of this thesis is to study and investigate one department of a SME -active intechnical documentation at railway industry-on the challenges of applying and implementing some strategic management tools on its organization. To understand these challenges, a business planning process has been designed, implemented and documented during the thesis. This process has given the author the ability to answer the research question based on limited experience from this especial case study. Ho...

  2. Analogies between Proofs - A Case Study

    OpenAIRE

    Melis, Erica

    1999-01-01

    This case study examines in detail the theorems and proofs that are shownby analogy in a mathematical textbook on semigroups and automata, thatis widely used as an undergraduate textbook in theoretical computer scienceat German universities (P. Deussen, Halbgruppen und Automaten, Springer1971). The study shows the important role of restructuring a proof for findinganalogous subproofs, and of reformulating a proof for the analogical trans-formation. It also emphasizes the importance of the rel...

  3. Preadolescent development: case studies in twins.

    OpenAIRE

    Frank, R. A.; Cohen, D. J.

    1980-01-01

    The authors studied eight sets of healthy twins, ranging in physical maturity from prepubertal to late pubertal, and their parents, to assess psychological changes in early adolescence. A phase-specific psychosocial regression correlates with the biological onset of puberty. We present preliminary findings related to twinship, parental reactions, and longitudinal development, based on detailed case studies. Parents experienced increased conflict, detachment, and pride in response to their twi...

  4. Study of enzyme replacement therapy for Gaucher Disease: comparative analysis of clinical and laboratory parameters at diagnosis and after two, five and ten years of treatment

    Directory of Open Access Journals (Sweden)

    Ana Maria Almeida Souza

    2014-10-01

    Full Text Available Objective: To evaluate the impact of enzyme replacement therapy for Gaucher Disease on clinical and laboratory parameters after two, five and ten years of treatment. Methods: Data were collected from patient records and analyzed using BioEstat software (version 5.0. Student's t-test, Analysis of Variance (ANOVA, Wilcoxon test and Kruskal–Wallis test were used for statistical analysis. Hepatomegaly and splenomegaly were analyzed using the Kappa test. Results: There was a significant increase in hemoglobin levels (p-value <0.01 and platelet counts (p-value = 0.01 within two years of therapy. At the same time, the frequencies of splenomegaly (p-value <0.01 and hepatomegaly (p-value <0.05 reduced. These results were similar at five and ten years of enzyme replacement therapy. Conclusions: There are substantial and quick (within two years laboratory and clinical responses to enzyme replacement therapy. These improvements continue as long as enzyme replacement therapy is administered every two weeks, as recommended by the literature.

  5. The Danish National Case Study Report

    DEFF Research Database (Denmark)

    Brodersen, Søsser; Jørgensen, Michael Søgaard

    facilities for organic food and the possibilities of local supply of organic food to the day-care centre. The third case is a co-operation between four RUC students and a local branch of a larger NGO working with nature and environment. This co-operation aims at investigating the pollution level in a village...... within their own research area, because they find the topic interesting or because they see the project as a possibility to recruit students for later thesis projects or research projects. The challenges in the co-operation with civil society groups are to secure the scientific level in the projects...... science through co-operation with Science Shops as a mediator between universities and civil society. The Danish national case study report analyses three projects carried out through the Science Shops at DTU and RUC. One case is a co-operation between two DTU students and an NGO, whom is working towards...

  6. Optimization case studies inthe NEOS guide.

    Energy Technology Data Exchange (ETDEWEB)

    Czyzyk, J.; Wieniewski, T.; Wright, S. J.; Mathematics and Computer Science; Wroclawska Szkola Jezykowa

    1999-03-01

    We describe several of the case studies in the NEOS Guide, a site on the World Wide Web that contains informational and educational material about optimization. These studies show how optimization relates to practical applications. They guide the user through relevant details of the application, formulation, solution, and interpretation of the results. The studies use interactivity to build intuition, allowing users to define their own problems and examine the corresponding solutions. The studies can be used for assignments in optimization and operations research courses and as small self-guided units equivalent to one or two lecture classes.

  7. Chloride Channel Myotonia: Study of Five Cases

    Directory of Open Access Journals (Sweden)

    M Ghofrani

    2002-09-01

    Full Text Available Chloride channel Myotonia is a form of channelopathy, and Myotonia is its manifestation. Myotonia may be defined as delayed relaxation of skeletal muscle after its contraction. Decreased chloride conductance across the transverse tubular system, renders the muscle membrane hyper-excitable and leads to repetitive firing, creating Myotonia. Myotonia congenital is another name for chloride channel Myotonia. Myotonia congenital appears in autosomal dominant type called Thomson disease, autosomal recessive type called Becker disease, and a type with sporadic occurrence. Symptoms appear in the first or second decade of life. Repeated muscle contraction, the so called warm up, result in resolution of the Myotonia stiffness. Muscle stiffness and hypertrophy is another finding at physical examination. In this study we report on 5 patients, which had clinical and electrical signs of Myotonia. Muscle hypertrophy and warm up phenomena were present in all cases. CPK measurement of all cases were normal. 2 patients underwent muscle biopsy that showed only atrophy and increased central nuclei. In three cases autosomal recessive inheritance (Becker, in one case autosomal dominant inheritance (Thomsen and in one case sporadic occurrence was suggested. With respect to successful results of carbamazepine therapy in 4 patients, and being excellent in one of them, we suggest carbamazepine for the first choice of Myotonia treatment.

  8. A case-control study of lung cancer relative to domestic radon exposure

    International Nuclear Information System (INIS)

    Public concern was expressed regarding the possibility of adverse health effects with the disposal of radioactive waste in Port Hope, Ontario. A case-control study was carried out to estimate the relative importance of domestic radon gas exposure in the causation of lung cancer in the town over a ten-year period. Twenty-seven cases met the entry criteria. Statistical analyses of results did not provide conclusive results that linked an increased risk of lung cancer and elevated domestic alpha radiation levels, when all factors were considered. However, a very strong association was demonstrated between cigarette smoking and lung cancer. (author)

  9. An Industrial Case Study for Scrum Adoption

    Directory of Open Access Journals (Sweden)

    Hassan Hajjdiab

    2012-01-01

    Full Text Available Agile software development methods and techniqueshave been demonstrated to improve employee morale, enhanceend-product quality, and achieve customer satisfaction. Agileadoption always comes with special challenges and thus fundamental organizational changes are necessary for successful outcome. In this paper we present an in-depth case study for adopting Scrum in a multi-team and multi-project situation to a government entity in the United Arab Emirates (U.A.E. While there are many successful stories for adopting Scrum in large and small organizations, there is little known about adoption stories in a multi-project/multi-team environments. In this paper we present a case study for an unsuccessful adoption of Scrum in a government entity in the U.A.E. The government entity under study have used the traditional waterfall approach for many years and decided to move to Agile software development method.This study highlights the challenges faced during the adoptionof Scrum method with recommendations to address them. Eachorganization has its unique properties and one case study is not enough to draw conclusions for the U.A.E environment. However, the results obtained from this paper help software engineers to better understand the development environment and context factors for software projects in the U.A.E and many lessons may be learned for future Agile adoption.

  10. Ten Tonne Plan: Education for Sustainability from a Whole Systems Thinking Perspective

    Science.gov (United States)

    Lewis, Elaine; Mansfield, Caroline; Baudains, Catherine

    2014-01-01

    The "Ten Tonne Plan" is a greenhouse gas emissions reduction initiative that aimed to reduce school emissions by 10 tonnes (metric tons) in one year. A case study was conducted on the impact of this initiative at a primary school in Western Australia. Research investigated student, staff, parent, and community partner perceptions…

  11. Enhancing Tourism Competitiveness of Hong Kong via Tourism Planning: A Comparative Case Study between Hong Kong and Singapore

    Directory of Open Access Journals (Sweden)

    Kaewta Muangasame

    2013-11-01

    Full Text Available This article aims to recommend tourism planning in Hong Kong (HK. A comparison case study of tourism planning between Singapore and Hong Kong is discussed. Secondary data from web sites, observations and in-depth interviews of ten residents and ten tourists was conducted to investigate tourism planning in the two countries. The study discloses that the HK government should consider adopting a long term oriented plan and implement an integrated approach with their tourism planning. Sustainability issues, land management and carrying capacity should be addressed by HK tourism planners. Lastly, re-structuring of the Tourism board should be considered to improve the efficacy of tourism planning of HK.

  12. The Pendulum A Case Study in Physics

    CERN Document Server

    Baker, Gregory L

    2005-01-01

    The pendulum: a case study in physics is a unique book in several ways. Firstly, it is a comprehensive quantitative study of one physical system, the pendulum, from the viewpoint of elementary and more advanced classical physics, modern chaotic dynamics, and quantum mechanics. In addition, coupled pendulums and pendulum analogs of superconducting devices are also discussed. Secondly, this book treats the physics of the pendulum within a historical and cultural context,showing, for example, that the pendulum has been intimately connected with studies of the earth's density, the earth's motion,

  13. Electronic Document Management: A Human Resource Management Case Study

    Directory of Open Access Journals (Sweden)

    Thomas Groenewald

    2004-11-01

    Full Text Available This case study serve as exemplar regarding what can go wrong with the implementation of an electronic document management system. Knowledge agility and knowledge as capital, is outlined against the backdrop of the information society and knowledge economy. The importance of electronic document management and control is sketched thereafter. The literature review is concluded with the impact of human resource management on knowledge agility, which includes references to the learning organisation and complexity theory. The intervention methodology, comprising three phases, follows next. The results of the three phases are presented thereafter. Partial success has been achieved with improving the human efficacy of electronic document management, however the client opted to discontinue the system in use. Opsomming Die gevalle studie dien as voorbeeld van wat kan verkeerd loop met die implementering van ’n elektroniese dokumentbestuur sisteem. Teen die agtergrond van die inligtingsgemeenskap en kennishuishouding word kennissoepelheid en kennis as kapitaal bespreek. Die literatuurstudie word afgesluit met die inpak van menslikehulpbronbestuur op kennissoepelheid, wat ook die verwysings na die leerorganisasie en kompleksietydsteorie insluit. Die metodologie van die intervensie, wat uit drie fases bestaan, volg daarna. Die resultate van die drie fases word vervolgens aangebied. Slegs gedeelte welslae is behaal met die verbetering van die menslike doeltreffendheid ten opsigte van elektroniese dokumentbestuur. Die klient besluit egter om nie voort te gaan om die huidige sisteem te gebruik nie.

  14. Waiting Lists for Radiation Therapy: A Case Study

    Directory of Open Access Journals (Sweden)

    Singer Peter A

    2001-04-01

    Full Text Available Abstract Background Why waiting lists arise and how to address them remains unclear, and an improved understanding of these waiting list "dynamics" could lead to better management. The purpose of this study is to understand how the current shortage in radiation therapy in Ontario developed; the implications of prolonged waits; who is held accountable for managing such delays; and short, intermediate, and long-term solutions. Methods A case study of the radiation therapy shortage in 1998-99 at Princess Margaret Hospital, Toronto, Ontario, Canada. Relevant documents were collected; semi-structured, face-to-face interviews with ten administrators, health care workers, and patients were conducted, audio-taped and transcribed; and relevant meetings were observed. Results The radiation therapy shortage arose from a complex interplay of factors including: rising cancer incidence rates; broadening indications for radiation therapy; human resources management issues; government funding decisions; and responsiveness to previous planning recommendations. Implications of delays include poorer cancer control rates; patient suffering; and strained doctor-patient relationships. An incompatible relationship exists between moral responsibility, borne by government, and legal liability, borne by physicians. Short-term solutions include re-referral to centers with available resources; long-term solutions include training and recruiting health care workers, improving workload standards, increasing compensation, and making changes to the funding formula. Conclusion Human resource planning plays a critical role in the causes and solutions of waiting lists. Waiting lists have harsh implications for patients. Accountability relationships require realignment.

  15. Compactified vacuum in ten dimensions

    International Nuclear Information System (INIS)

    Since the 1920's, theories which unify gravity with the other fundamental forces have called for more than the four observed dimensions of space-time. According to such a theory, the vacuum consists of flat four-dimensional space-time described by the Minkowski metric M4 and a compactified space B. The dimensions of B are small, and the space can only be observed at distance scales smaller than the present experimental limit. These theories have had serious difficulties. The equations of gravity severely restrict the possible choices for the space B. The allowed spaces are complicated and difficult to study. The vacuum is furthermore unstable in the sense that a small perturbation causes the compactified dimensions to expand indefinitely. There is an addition a semi-classical argument which implies that the compactified vacuum by annihilated by virtual black holes. It follows that a universe with compactified extra dimensions could not have survived to the present. These results were derived by applying the equations of general relativity to spaces of more than four dimensions. The form of these equations was assumed to be unchanged by an increase in the number of dimensions. The authors illustrate the effect of such terms by considering the example B = S6 where S6 is the six-dimensional sphere. Only when the extra terms are included is this choice of the compactified space allowed. He explore the effect of a small perturbation on such a vacuum. The ten-dimensional spherically symmetric potential is examined, and I determine conditions under which the formation of virtual black holes is forbidden. The examples M4 x S6 is still plagued by the semi-classical instability, but this result does not hold in general. The requirement that virtual black holes be forbidden provides a test for any theory which predicts a compactified vacuum

  16. Poverty, growth and redistribution: A case study of Iran

    OpenAIRE

    Assadzadeh, Ahmad; Paul, Satya

    2001-01-01

    This study examines the changes in the extent of poverty in Iran during the post-Islamic period. More specifically, it investigates the contributions of growth and redistribution factors to changes in poverty over a period of ten years (1983 to 1993). The analysis is based on household level data relating to three consecutive household income and expenditures surveys of 1983, 1988 and 1993. The study reveals that over a period of ten years, the extent of poverty in the rural area has declined...

  17. Ten questions about systems biology

    DEFF Research Database (Denmark)

    Joyner, Michael J; Pedersen, Bente K

    In this paper we raise 'ten questions' broadly related to 'omics', the term systems biology, and why the new biology has failed to deliver major therapeutic advances for many common diseases, especially diabetes and cardiovascular disease. We argue that a fundamentally narrow and reductionist...

  18. Ten challenges to transform Taxonomy

    OpenAIRE

    Quentin D. Wheeler; Valdecasas, Antonio G.

    2005-01-01

    [EN] Taxonomy is at a crossroads. Although taxonomy has an impressive past, having documented and organized knowledge of nearly two million species, most of the basic work required to describe Earth’s biodiversity remains undone. Factors that guide the choices of research topics in science are considered. Ten challenges are presented to the taxonomic community that we believe will accelerate its revitalization.

  19. Czech Experience with Broader Case Studies Implementation

    Directory of Open Access Journals (Sweden)

    Martina Fischerová

    2013-06-01

    Full Text Available The Czech education system is influenced by various conditions that have impact also on the further development of higher education in the Czech Republic. Within the educational process, the shift from passive learning methods (teaching to active teaching methods (learning is still obvious. The shift itself places higher requirements on both pedagogical staff skills and their networking ability Important factor for the teachers is getting real data from Czech companies in order to prepare tailor made case studies from the Czech environment. The main aim of this paper is to highlight and analyze the complexity of experience with case studies implementation into the Czech higher education system from various perspectives of selected stakeholders (university, students, companies.

  20. Management & Communication: Project Management Case Study

    CERN Multimedia

    Nathalie Dumeaux

    2004-01-01

    We are pleased to announce the recent launch of a new workshop on Project Management. This is designed for People with budgetary, scheduling and/or organizational responsibilities in a project or a sub-project. The objectives through a management case study specially suited to CERN are: to become familiar with modern management techniques in use for structuring, planning, scheduling, costing and progress monitoring of a project or a sub-project. to understand in-depth issues associated with Deliverable-oriented Project Management, Earned Value Management, Advanced Project Cost Engineering and Project Risk Management. The full description of this workshop can be found here. The next session will be held on 8 October 2004. If you are interested in this workshop, please contact Nathalie Dumeaux, email or 78144. Programme of Seminars October to December 2004 Situation : 21.09.2004 Séminaires bilingues Dates Jours Places disponibles Project Management Case study 8 October 1 oui Intr...

  1. Case Study: Revising a Formal Case Study Presentation as an Independent Research Project

    Science.gov (United States)

    Field, Patrick R.

    2013-01-01

    This article examines the process of researching and revising a case study presentation on an individual who experienced anesthetic awareness during an abdominal surgery and eventually committed suicide. Topics addressed include the author's selection of an undergraduate student with a science and teaching background to work on the case…

  2. A Case Study: action based Entrepreneurship Education

    OpenAIRE

    Jacobsen, Petter Jacob

    2011-01-01

    This paper contributes by providing suggestions on how to analyze business ideas forexploitation in an entrepreneurial education context, and how the institution can provide support activities to enhance the chance of successful exploitation. Active learning has become the preferred choice of teaching entrepreneurship and external ideas are used to provide the students with business opportunities to exploit. An instrumentaø case study on the Norwegian University of Science and Technology...

  3. Case study: Wireless Sensor Networks Technology

    OpenAIRE

    Naveen Jain; Pawan Shakdwipee; Sunil Sharma

    2013-01-01

    This paper present the history of research in sensor networks over the past decades, including two important programs of the Defense Advanced Research Projects Agency (DARPA), and the Distributed Sensor Networks (DSN) and the Sensor Information Technology (SensIT) programs. Technology trends that impact the development of sensor networks are reviewed, and new applications such as infrastructure security, habitat monitoring. The paper concludes by presenting some recent case studies results in...

  4. Power and organisational change: a case study

    OpenAIRE

    João Pedro Oliveira

    2010-01-01

    This thesis reports the results of a case study conducted in a Portuguese manufacturing organization, a part of a large group, which endured profound organizational changes. The initial objective of the research was to explore, in a processual way, the long-term interactions between an Enterprise Resource Planning (ERP) system, the consultants that implemented it and management accounting and control, in this organization. However, during the fieldwork, the researcher was confronted with an a...

  5. Customer Buying Behavior : Case Study: Algol Technics

    OpenAIRE

    Weckman, Nina

    2009-01-01

    The purpose of this study is to research the customer buying behavior in a specific market. This thesis is made for a subgroup of Algol Technics which specializes in the marketing of driver seats. The research areas included brand recognition, price and quality, as well as the communications channels. The theoretical framework presented consists of the marketing strategies, marketing mix, Porter’s five forces analysis, customer relationship marketing, and market analysis. The case compan...

  6. Concentrated Photo Voltaics (CPV: a case study

    Directory of Open Access Journals (Sweden)

    Centro S.

    2015-01-01

    Full Text Available Concentrated PhotoVoltaic (CPV, among green energy solutions, nowadays has the ambition to reach grid-parity without subside. CPV substitutes large areas of expensive semiconductor solar cells, with concentrating optics made of cheap materials. Moreover the cells that are suitable for CPV exhibits an unprecedented efficiency and their technology is progressing every year. A case study project, TwinFocus®, will be presented in detail.

  7. Maternal Health: A Case Study of Rajasthan

    OpenAIRE

    Iyengar, Sharad D.; Iyengar, Kirti; Gupta, Vikram

    2009-01-01

    This case study has used the results of a review of literature to understand the persistence of poor maternal health in Rajasthan, a large state of north India, and to make some conclusions on reasons for the same. The rate of reduction in Rajasthan's maternal mortality ratio (MMR) has been slow, and it has remained at 445 per 1000 livebirths in 2003. The government system provides the bulk of maternal health services. Although the service infrastructure has improved in stages, the availabili...

  8. Marketing and clinical trials: a case study

    OpenAIRE

    Entwistle Vikki A; Snowdon Claire; Garcia Jo; Knight Rosemary C; Shakur Haleema; Elbourne Diana R; Roberts Ian; Francis David; McDonald Alison M; Grant Adrian M; Campbell Marion K

    2007-01-01

    Abstract Background Publicly funded clinical trials require a substantial commitment of time and money. To ensure that sufficient numbers of patients are recruited it is essential that they address important questions in a rigorous manner and are managed well, adopting effective marketing strategies. Methods Using methods of analysis drawn from management studies, this paper presents a structured assessment framework or reference model, derived from a case analysis of the MRC's CRASH trial, o...

  9. Case Study for Holylight(HK)

    OpenAIRE

    Ha, Kong Ho

    2013-01-01

    In this thesis the case company – Holylight (HK) was thoroughly studied. The company structure, business strategic management and Marketing mix (4ps) were analyzed using SWOT analysis. It was found that Holylight (HK) had huge poten-tial in the business its stable supplies from the United States of America, Europe and Australia; Alliance partnership company ensure the steady sales channel in potential market – China that further development and expansion are highly feasible. However th...

  10. Harm reduction: Australia as a case study.

    OpenAIRE

    Wodak, A

    1995-01-01

    This paper explicates the term, "harm reduction"; demonstrates that harm reduction has a long tradition; and uses one country, Australia, as a case study. Harm reduction can be understood as "policies and programs which are designed to reduce the adverse consequences of mood altering substances without necessarily reducing their consumption"; it is consistent with the best traditions of both medicine and public health. Although it is difficult to interpret trends in mortality from alcohol, to...

  11. Arithmetic in Metamath, Case Study: Bertrand's Postulate

    OpenAIRE

    Carneiro, Mario

    2015-01-01

    Unlike some other formal systems, the proof system Metamath has no built-in concept of "decimal number" in the sense that arbitrary digit strings are not recognized by the system without prior definition. We present a system of theorems and definitions and an algorithm to apply these as basic operations to perform arithmetic calculations with a number of steps proportional to an arbitrary-precision arithmetic calculation. We consider as case study the formal proof of Bertran...

  12. Corporate Government Strategy Development: A Case Study

    OpenAIRE

    Ali M. Al-Khouri

    2012-01-01

    In this article, we present a case study of one the successful government organisation strategy development exercises in the United Arab Emirates (UAE). The 2010-2013 strategy of Emirates Identity Authority (Emirates ID) supported organisational development and allowed the Emirates ID to become a pioneer in its field of practice. Its strategy was among the reasons behind its selection and winning the Best Federal Authority Award in the 2012 UAE's federal Government Excellence Programme. This ...

  13. A warehouse design decision model: case study

    OpenAIRE

    Geraldes, Carla A. S.; Carvalho, Maria do Sameiro; Pereira, Guilherme

    2008-01-01

    Today’s competitive and volatile market requires flexibility, quality and efficiency from the logistics operations. In this context, warehouses are an important link of the logistic chain and warehouse management plays an important role over customer's service. Throughout this work we analyze a mathematical model aiming to support warehouse management decisions. A case study is used for that purpose and the model jointly identifies product allocation to the functional areas in the warehouse, ...

  14. Hypohidrotic ectodermal dysplasia - A Case Study

    Directory of Open Access Journals (Sweden)

    Pradeesh Sathyan

    2011-01-01

    Full Text Available Hereditary Ectodermal Dysplasia is an inherited disorder involving skin, teeth, hair and nails.Hypohidrotic ectodermal dysplasia or Anhydrotic ectodermal dysplasia is the most common syndromeamong this large group of heriditory disorders. Hypohidrosis, hypotrichosis and hypodontia constitutethe main symptoms of the syndrome. The case study of a 17 year old boy, a vibrant youngster with nopositive family history is presented. The pattern of genetic inheritance is also discussed.

  15. Mobile phone surveys: the Slovenian case study:

    OpenAIRE

    Batagelj, Zenel; Belak, Eva; ?iki?, Sanja; VEHOVAR Vasja

    2004-01-01

    In 2004, the number of mobile phone subscriptions in Slovenia reached the total number of inhabitants. Consequently, the fixed telephone coverage has started to decline; almost 10% of households are now available only over the mobile phone. With this, Slovenia positions itself as a typical EU country and can serve as a case study for issues related to mobile phone interview surveys. The paper addresses the general context of mobile phone usage and the calculations of mobile phone coverage rat...

  16. Spicy Stonehenge: Proposing a SOA Case Study:

    OpenAIRE

    Espinha, T.A.; Chen, C; Zaidman, A.E.; Gross, H.G.

    2012-01-01

    Prepint of paper published in: ICSE Workshop on Principles of Engineering Service Oriented Systems (PESOS), 4 June 2012; doi:10.1109/PESOS.2012.6225940 Maintenance research in the context of Service Oriented Architecture (SOA) is currently lacking a suitable standard case study that can be used by scientists in order to (1) develop and assess their research ideas and (2) compare and benchmark their solution(s). It is also well established in different fields that having such a standard ca...

  17. RECURRENT PERINATAL LOSS: A CASE STUDY*

    OpenAIRE

    KAVANAUGH, KAREN; ROBERTSON, PAMELA A.

    1999-01-01

    To date, investigators have not demonstrated a clear relationship between a parent’s history of prior perinatal losses and intensity of grief response following a subsequent perinatal loss. Examining this relationship for low-income, African-American parents is important because they are a vulnerable population due to the high incidence of perinatal mortality in Blacks and their other life stressors that can impact on grief response and caring needs. The purpose of this case study was to exam...

  18. An Industrial Case Study for Scrum Adoption

    OpenAIRE

    Hassan Hajjdiab; Al Shaima Taleb; Jauhar Ali

    2012-01-01

    Agile software development methods and techniqueshave been demonstrated to improve employee morale, enhanceend-product quality, and achieve customer satisfaction. Agileadoption always comes with special challenges and thus fundamental organizational changes are necessary for successful outcome. In this paper we present an in-depth case study for adopting Scrum in a multi-team and multi-project situation to a government entity in the United Arab Emirates (U.A.E). While there are many successfu...

  19. Gamification in teaching music : case study

    OpenAIRE

    Gomes, Cristina; Figueiredo, Mauro; Bidarra, José

    2014-01-01

    The study presented here aims to assess the quality of learning that occurred by the introduction of an educational application in the teaching/learning process of music education – 2nd cycle of basic education. The investigation focused on the use of a set of multimedia materials designed to provide support for instrumental practice (recorder and guitar) and backing vocals, according to the technique of the sing along. The students had access to the materials in two ways: in the first case, ...

  20. Credit in rural India: a case study

    OpenAIRE

    Dreze, Jean; Lanjouw, Peter; Sharma, Naresh

    1997-01-01

    This paper presents a case study of credit transactions in Palanpur, a north Indian village. Drawing on detailed informtion from all borrowers and lenders in the village, we examine a number of issues related to the functioning of rural credit markets. These include the segmentation of the credit market, the achievements and failure of public lending institutions, the role of interest-free lending, the lending strategies of village moneylenders, social inequalities in access to credit, and th...

  1. Sealed-Bid Auctions: Case Study

    OpenAIRE

    Van Schaik, F.D.J.; Kleijnen, J.P.C.

    2001-01-01

    Auctions are an important link in supply chains.This paper presents an empirical investigation of a single-shot simultaneous or sealed-bid auction.This case study concerns the mussel trade in Yerseke, the Netherlands.It surprisingly demonstrates that companies buying large quantities of mussels pay higher unit prices.It also reveals that auction prices react sharply to changes in annual supply and that seasonality causes a bullwhip effect.Finally, purchase managers perform significantly diffe...

  2. Antineutrino reactor safeguards - a case study

    OpenAIRE

    Christensen, Eric; Huber, Patrick; Jaffke, Patrick

    2013-01-01

    Antineutrinos have been proposed as a means of reactor safeguards for more than 30 years and there has been impressive experimental progress in neutrino detection. In this paper we conduct, for the first time, a case study of the application of antineutrino safeguards to a real-world scenario - the North Korean nuclear crisis in 1994. We derive detection limits to a partial or full core discharge in 1989 based on actual IAEA safeguards access and find that two independent me...

  3. Private power financing: a case study

    International Nuclear Information System (INIS)

    The Public Utility Regulatory Power Act (PURPA) in the USA and the UK's Electricity Act passed in 1989 are discussed and the first UK private power project is considered. A case study is presented, and covers the questions of when to approach the bank; banker versus investment bank; project fundamentals; the sponsor and the management team; the strength of the key project agreements; syndication of the project debt; and bank support during construction and operation. (author)

  4. Concentrated Photo Voltaics (CPV): a case study

    Science.gov (United States)

    Centro, S.

    2015-08-01

    Concentrated PhotoVoltaic (CPV), among green energy solutions, nowadays has the ambition to reach grid-parity without subside. CPV substitutes large areas of expensive semiconductor solar cells, with concentrating optics made of cheap materials. Moreover the cells that are suitable for CPV exhibits an unprecedented efficiency and their technology is progressing every year. A case study project, TwinFocus®, will be presented in detail.

  5. Case Study on Inventory Management Improvement

    OpenAIRE

    Plinere Darya; Borisov Arkady

    2015-01-01

    Inventory management is a challenging problem area in supply chain management. Companies need to have inventories in warehouses in order to fulfil customer demand, meanwhile these inventories have holding costs and this is frozen fund that can be lost. Therefore, the task of inventory management is to find the quantity of inventories that will fulfil the demand, avoiding overstocks. This paper presents a case study for the assembling company on inventory management. It is proposed to use inve...

  6. Customer Buying Behavior : Case Study: Algol Technics

    OpenAIRE

    Weckman, Nina

    2009-01-01

    The purpose of this study is to research the customer buying behavior in a specific market. This thesis is made for a subgroup of Algol Technics which specializes in the marketing of driver seats. The research areas included brand recognition, price and quality, as well as the communications channels. The theoretical framework presented consists of the marketing strategies, marketing mix, Porter’s five forces analysis, customer relationship marketing, and market analysis. The case compan...

  7. BOOK REVIEW: Case Studies in Knowledge Management

    OpenAIRE

    BOYACI, Reviewed By Dr. Adnan

    2005-01-01

    161Case Studies in Knowledge ManagementEdited by Murray JennexHersley: PA: Idea Group, 2005, pp. 372, ISBN 1-59140-352-9Reviewed by Dr. Adnan BOYACIAnadolu UniversityEskişehir-TurkeyKnowledge management (KM) as a structured system and the way to the effectiveness isrelatively new field for the contemporary organizations functioning in different andcompetitive domain of public and private sectors in terms of getting optimal effectivenessunderlined by the concepts such as quality, productivity…...

  8. Systemic Design: Two Canadian Case Studies

    Directory of Open Access Journals (Sweden)

    Alex Ryan

    2014-12-01

    Full Text Available This paper introduces two novel applications of systemic design to facilitate a comparison of alternative methodologies that integrate systems thinking and design. In the first case study, systemic design helped the Procurement Department at the University of Toronto re-envision how public policy is implemented and how value is created in the broader university purchasing ecosystem. This resulted in an estimated $1.5 million in savings in the first year, and a rise in user retention rates from 40% to 99%. In the second case study, systemic design helped the clean energy and natural resources group within the Government of Alberta to design a more efficient and effective resource management system and shift the way that natural resource departments work together. This resulted in the formation of a standing systemic design team and contributed to the creation of an integrated resource management system. A comparative analysis of the two projects identifies a shared set of core principles for systemic design as well as areas of differentiation that reveal potential for learning across methodologies. Together, these case studies demonstrate the complementarity of systems thinking and design thinking, and show how they may be integrated to guide positive change within complex sociotechnical systems.

  9. Shuttle Transportation System Case-Study Development

    Science.gov (United States)

    Ransom, Khadijah

    2012-01-01

    A case-study collection was developed for NASA's Space Shuttle Program. Using lessons learned and documented by NASA KSC engineers, analysts, and contractors, decades of information related to processing and launching the Space Shuttle was gathered into a single database. The goal was to provide educators with an alternative means to teach real-world engineering processes and to enhance critical thinking, decision making, and problem solving skills. Suggested formats were created to assist both external educators and internal NASA employees to develop and contribute their own case-study reports to share with other educators and students. Via group project, class discussion, or open-ended research format, students will be introduced to the unique decision making process related to Shuttle missions and development. Teaching notes, images, and related documents will be made accessible to the public for presentation of Space Shuttle reports. Lessons investigated included the engine cutoff (ECO) sensor anomaly which occurred during mission STS-114. Students will be presented with general mission infom1ation as well as an explanation of ECO sensors. The project will conclude with the design of a website that allows for distribution of information to the public as well as case-study report submissions from other educators online.

  10. Ten past and ten future GAS/MAUS-payloads

    Science.gov (United States)

    Staniek, S.; Otto, G.; Doepkess, J.

    1988-01-01

    MAUS (materials science autonomous experiments) is one out of a series of flight opportunities which the Space Program of West Germany offers to scientists from the disciplines of materials research and processing for performing materials science investigations under microgravity conditions. Up to now, ten MAUS experiments were flown which were dealing with the following scientific topics: decomposition of binary alloys with miscibility gap in the liquid state, interaction of a solidification front with dispersed particles, critical Marangoni number, investigation of the magnetic compound MnBi, shrinkage of gas bubbles in glass melts and slip casting. The ten future experiments are partly reflights with modification of the scientific objectives as well as new experiments in the fields of chemical reactions, heat transfer, glass technology and Ostwald ripening. Looking to ten flown payloads, the peculiarities of instrument technology in GAS-cans and its evolution is discussed with emphasis on structure, electronics and thermal design. A typical modern payload using 100 percent of the resource is presented.

  11. Capturing Cultural Glossaries: Case-study II

    Directory of Open Access Journals (Sweden)

    Matete Madiba

    2011-10-01

    Full Text Available

    ABSTRACT: This case-study attempts to present a brief glossary of Northern Sotho medical terms. It is a follow-up of a similar case-study (Madiba, Mphahlele and Kganyago 2003, which was an attempt to capture and present Northern Sotho cooking terms. Case-study I consists of the names for utensils, ingredients and the processes involved in the preparation of cultural dishes. With both these case-studies, the intention has been to use the opportunities availing themselves for the pres-ervation and valorisation of Northern Sotho, including the extension of its corpora to support national dictionary-making processes. The case-study methodology has been very useful for the purposes of this project and the context within which it was undertaken. It aims to provide a model for the collection and presentation of authentic Northern Sotho terminology which otherwise would hardly have been accessible.

    Keywords: CULTURAL GLOSSARY, INDIGENOUS KNOWLEDGE SYSTEMS, CORPUS, OUTCOMES-BASED EDUCATION, ASSESSMENT CRITERIA, TRADITIONAL MEDICAL TERMS, COMMUNICATIVE APPROACH, STRUCTURAL APPROACH, METONYMY, HANDS-ON ACTIVITIES, TASK-BASED LEARNING

    *****

    OPSOMMING: Die totstandbrenging van kulturele woordversamelings: Ge-vallestudie II. Hierdie gevallestudie probeer om 'n beperkte woordelys van Noord-Sotho- mediese terme aan te bied. Dit is 'n voortsetting van 'n soortgelyke gevallestudie (Madiba, Mpha-hlele en Kganyago 2003 wat 'n poging was om Noord-Sothokookterme te versamel en aan te bied. Gevallestudie I bestaan uit die name van gereedskap, bestanddele, en die prosesse betrokke by die voorbereiding van kulturele geregte. Met altwee hierdie gevallestudies was die bedoeling om die geleenthede te gebruik wat hulleself aanbied vir die bewaring en bestendiging van Noord-Sotho, insluitende die uitbreiding van sy korpora om die nasionale woordeboeksamestellingsprosesse te ondersteun. Die gevallestudiemetodologie was baie nuttig vir die doeleindes van hierdie projek en die konteks waarin dit onderneem is. Dit beoog om 'n model te verskaf vir die versameling en aanbieding van Noord-Sothoterminologie wat andersins skaars toeganklik sou gewees het.

    Sleutelwoorde: KULTURELE WOORDVERSAMELING, INHEEMSE KENNISSTELSELS, KORPUS, UITKOMSGEBASEERDE ONDERWYS, WAARDEBEPALINGSKRITERIA, TRADISIO-NELE MEDIESE TERME, KOMMUNIKATIEWE BENADERING, STRUKTURELE BENADERING, METONIMIE, PRAKTIESE WERKSAAMHEDE, TAAKGEBASEERDE LEERWYSE

  12. Case studies in atomic collision physics

    CERN Document Server

    McDaniel, E W

    2013-01-01

    Case Studies in Atomic Collision Physics II focuses on studies on the role of atomic collision processes in astrophysical plasmas, including ionic recombination, electron transport, and position scattering. The book first discusses three-body recombination of positive and negative ions, as well as introduction to ionic recombination, calculation of the recombination coefficient, ions recombining in their parent gas, and three-body recombination at moderate and high gas-densities. The manuscript also takes a look at precision measurements of electron transport coefficients and differential cr

  13. Corporate Valuation : A case study of Unibet

    OpenAIRE

    Davidsson, Marcus; Bertilsson, Jonas

    2005-01-01

    Problem: The online betting industry has erased the importance of national borders and opened up the world, which has lead to a more diversified perspective of the company. In this master thesis we wanted to broaden and develop the topic of corporate valuation with regard to the on-line gambling industry. In order to do that, a case study of the on-line betting firm Unibet and its core betting activities has been carried out. Purpose: The study aims to identify factors in the strategic, SWOT ...

  14. Estudio de diez años sobre variedades de tumores de parótida en pediatría Ten-year study on varieties of parotid tumors in pediatrics

    Directory of Open Access Journals (Sweden)

    Caridad Verdecia Cañizares

    2012-06-01

    Full Text Available Los tumores de parótida en pediatría son infrecuentes, pues constituyen aproximadamente el 0,5 % de todos los cánceres. Se presentan, generalmente, como un aumento de volumen local y asintomático, otras veces se acompañan de dolor y signos inflamatorios. Se realizó un estudio retrospectivo, longitudinal y descriptivo, para determinar la frecuencia y formas de presentación de los tumores de parótida diagnosticados en pacientes con edades comprendidas de 0 a 18 años, que han sido ingresados en el servicio de oncocirugía del Hospital "William Soler", entre febrero del año 2001 y diciembre de 2010, teniendo en cuenta: sexo, las formas de presentación, respuesta al tratamiento, así como las variantes histológicas presentadas, con el objetivo de dar a conocer estas variantes de tumores de parótida en pediatría, que, a pesar de ser infrecuentes, cuando se presentan constituyen un grupo de alto riesgo. Se diagnosticaron 7 pacientes, de los cuales 3 fueron adenomas pleomorfos, un adenocarcinoma, un carcinoma mucoepidermoide de la glándula, un linfoma de Hodgkin parotídeo y un tumor mixto con células atípicas de la glándula. El inicio de todos fue la presencia de una masa parotídea, en 6 de los casos asintomáticos, y en un caso con dolor local. Se le realizó ultrasonido de la glándula y biopsia aspirativa con aguja fina a todos los pacientes. El sexo masculino predominó sobre el femenino en una proporción 5 a 2, la edad media de presentación fue 12,3 años. La cirugía es el arma terapéutica principal en la mayoría de los casos. Se recomienda el seguimiento estrecho de los pacientes por el alto índice de recurrencia local.Parotid tumors are uncommon because they account for 0.5 % of all types of cancer in pediatrics. They generally occur as increased local asymptomatic volume, occasionally accompanied by pain and inflammatory signs. A retrospective, longitudinal and descriptive study was carried out to determine the frequency and forms of presentation of parotid tumors diagnosed in 0-18 years-old patients, who had been admitted to the oncological surgery service of "William Soler" pediatric hospital from February 2001 to December 2010. The variables taken into account were sex, forms of presentation, response to treatment as well as the histological variants presented, with the objective of giving information about these variants of parotid tumors in pediatrics, which, despite their rareness, represent a high risk group when occur. Seven patients were diagnosed, of whom 3 were pleomorphic adenomas, one adenocarcinoma, one mucoepidermoid carcinoma of the gland, one parotid Hodgkin lymphoma and one mixed tumor with atypical cells of the gland. The onset of all the tumors was the presence of a parotid mass in 6 asymptomatic cases and in one case suffering local pain. They were all performed gland ultrasound and aspiration fine needle biopsy. Males prevailed over the females (ratio of 5:2 and the average age of presentation was 12.3 years. Surgery is the main therapeutic weapon in most of cases. It was recommended to closely follow the patients because of their high rate of local recurrence.

  15. Estudio de diez años sobre variedades de tumores de parótida en pediatría / Ten-year study on varieties of parotid tumors in pediatrics

    Scientific Electronic Library Online (English)

    Caridad, Verdecia Cañizares; Osiris, Cubero Meléndez; Magda, Alonso Pírez; Andrés Manuel, Portugués Díaz.

    2012-06-01

    Full Text Available Los tumores de parótida en pediatría son infrecuentes, pues constituyen aproximadamente el 0,5 % de todos los cánceres. Se presentan, generalmente, como un aumento de volumen local y asintomático, otras veces se acompañan de dolor y signos inflamatorios. Se realizó un estudio retrospectivo, longitud [...] inal y descriptivo, para determinar la frecuencia y formas de presentación de los tumores de parótida diagnosticados en pacientes con edades comprendidas de 0 a 18 años, que han sido ingresados en el servicio de oncocirugía del Hospital "William Soler", entre febrero del año 2001 y diciembre de 2010, teniendo en cuenta: sexo, las formas de presentación, respuesta al tratamiento, así como las variantes histológicas presentadas, con el objetivo de dar a conocer estas variantes de tumores de parótida en pediatría, que, a pesar de ser infrecuentes, cuando se presentan constituyen un grupo de alto riesgo. Se diagnosticaron 7 pacientes, de los cuales 3 fueron adenomas pleomorfos, un adenocarcinoma, un carcinoma mucoepidermoide de la glándula, un linfoma de Hodgkin parotídeo y un tumor mixto con células atípicas de la glándula. El inicio de todos fue la presencia de una masa parotídea, en 6 de los casos asintomáticos, y en un caso con dolor local. Se le realizó ultrasonido de la glándula y biopsia aspirativa con aguja fina a todos los pacientes. El sexo masculino predominó sobre el femenino en una proporción 5 a 2, la edad media de presentación fue 12,3 años. La cirugía es el arma terapéutica principal en la mayoría de los casos. Se recomienda el seguimiento estrecho de los pacientes por el alto índice de recurrencia local. Abstract in english Parotid tumors are uncommon because they account for 0.5 % of all types of cancer in pediatrics. They generally occur as increased local asymptomatic volume, occasionally accompanied by pain and inflammatory signs. A retrospective, longitudinal and descriptive study was carried out to determine the [...] frequency and forms of presentation of parotid tumors diagnosed in 0-18 years-old patients, who had been admitted to the oncological surgery service of "William Soler" pediatric hospital from February 2001 to December 2010. The variables taken into account were sex, forms of presentation, response to treatment as well as the histological variants presented, with the objective of giving information about these variants of parotid tumors in pediatrics, which, despite their rareness, represent a high risk group when occur. Seven patients were diagnosed, of whom 3 were pleomorphic adenomas, one adenocarcinoma, one mucoepidermoid carcinoma of the gland, one parotid Hodgkin lymphoma and one mixed tumor with atypical cells of the gland. The onset of all the tumors was the presence of a parotid mass in 6 asymptomatic cases and in one case suffering local pain. They were all performed gland ultrasound and aspiration fine needle biopsy. Males prevailed over the females (ratio of 5:2) and the average age of presentation was 12.3 years. Surgery is the main therapeutic weapon in most of cases. It was recommended to closely follow the patients because of their high rate of local recurrence.

  16. Quality assurance of hazard and operability (HAZOP) study performance in the context of offshore safety case assessment. A feasibility study

    Energy Technology Data Exchange (ETDEWEB)

    Rushton, A.G.

    1996-01-01

    The subject of the study was the feasibility of the quality assurance of hazard and operability studies (HAZOPs) within the context of their possible usage in Offshore Safety Cases (OSCs). HAZOP is one technique that could be put forward in partial fulfilment of the requirement in the Offshore Installations (Safety Case) Regulation 1992 [1] to identify all hazards with the potential to cause a major accident, but its use is not mandatory. The study was carried out in three phases. The framework within which quality assurance of HAZOP might be carried out was explored; in addition, experience from Voluntary Safety Cases (VSCs) was reviewed. The current practices and views of a sample of ten operating companies were surveyed. Finally, proposals for a means of HAZOP QA were considered and the basis of a scheme for HAZOP QA was developed. (author)

  17. Mycetoma in Iran: Study of 62 Cases

    Directory of Open Access Journals (Sweden)

    S.J. Hashemi

    2008-01-01

    Full Text Available This research presents a retrospective study of 62 cases of mycetoma in Iran that were diagnosed clinically and microbiologically from 1972 to 2005. In 1972 mycetoma has been first report in Iran by medical mycology department of Tehran University. We retrospectively compared the overall prevalence of mycetoma and the prevalence of infective agent in Iran during 33 years. In this study age, sex, job, infective agent and anatomical site of infection have been considered. Retrospective analysis of the records revealed that the ratio of actinomycetoma and eumycetoma was 42:20 that differed significantly (p < 0.01. Actinomadura madurae (n = 11 in actiomycetoma and Psudallescheria boydii (n = 9 in eumycetoma were predominant agents. The male to female ratio was 41:21 and the peak age for infection was between 40-50 years old but there is no a significant differences between age groups (p > 0.05 and the earliest age of onset was 18 and the latest 65.The single most common site of infection is foot but generally hand and other limbs can infected and 54.4% of infected area was in palm and disease can infected other area with less frequency. A total of 49 cases were pedal mycetoma and 13 cases were in extra pedal areas. The results show that farmers with 45.2% are at greater occupation risk of mycetoma (p < 0.01.

  18. Case-control studies of screening procedures.

    Science.gov (United States)

    Knox, G

    1991-01-01

    Case-control studies of different screening procedures have been reported. Cases of the detectable disease, and controls without the disease, were compared with respect to their previous screening histories. Measures of the protective value of the test were calculated from the difference. The inductive basis of these studies is re-examined and it is concluded that all claims to have measured the protective value of a screening test through such means are potentially or actually flawed. The reasons for the inductive failures are: (a) The ratio between the retrospective screening frequencies depends critically upon unmeasured parameters other than procedural efficacy; the ratio is therefore not capable on its own of providing an estimate of the protection afforded: (b) Almost all screens among reported case and control groups have been negative, and it is a matter of prior fact that a negative test does not protect anyone. Only the positive tests protect. Direct analogies with drug and vaccine trials, from which the concept of a 'protective value' originates, are therefore false. PMID:2008504

  19. Improving Computer-Mediated Synchronous Communication of Doctors in Rural Communities Through Cloud Computing: A Case Study of Rural Hospitals in South Africa

    OpenAIRE

    Alfred Coleman; Marlien E Herselman; Mary Coleman

    2012-01-01

    This paper investigated how doctors in remote rural hospitals in South Africa use computer-mediated tool to communicate with experienced and specialist doctors for professional advice to improve on their clinical practices. A case study approach was used. Ten doctors were purposively selected from ten hospitals in the North West Province. Data was collected using semi-structured open ended interview questions. The interviewees were asked to tell in their own words the averag...

  20. The case study of biomaterials and biominerals

    Science.gov (United States)

    Del Hoyo Martínez, Carmen

    2013-04-01

    The teaching of biomaterials as case study by on-line platform , susceptible to develop both individually and in groups, got different objectives proposed by the European Higher Education System, among which include: participate actively in the teaching-learning process by students, interpreting situations, adapt processes and solutions. It also improves oral and written communication, analytical skills and synthesis and also the ability to think critically. Biomaterials have their origin in biominerals. These are solid inorganic compounds of defined structure, consisting of molecular control mechanisms that operate in biological systems. Its main functions are: structural support, a reservoir of essential elements, sensors, mechanical protection and storage of toxic elements. Following the demand of materials compatible with certain functional systems of our body, developed biomaterials. Always meet the condition of biocompatibility. Should be tolerated by the body and do not provoke rejection. This involves a comprehensive study of physiological conditions and the anatomy of the body where a biomaterial has to be implemented. The possibility of generating new materials from biominerals has a major impact in medicine and other fields could reach as geology, construction, crystallography, etc. While the study of these issues is in its infancy today, can be viewed as an impact on the art and future technology. Planning case study that students would prepare its report for discussion in subgroups. Occurs then the pooling of individual analysis, joint case discussion and adoption by the subgroup of a consensual solution to the problem. The teacher as facilitator and coordinator of the final case analysis, sharing leads to group-wide class and said the unanimous decision reached by the students and gives his opinion on the resolution of the case. REFERENCES D.P. Ausubel. Psicología Educativa. Un punto de vista cognoscitivo. Trillas. Ed. 1983. E.W. Eisner. Procesos cognitivos y currículum. Una base para decidir lo que hay que enseñar. Martínez Roca Ed. 1987. C.O. Oriakhi. Polymer Nanocomposition Approach to Advanced Materials, Journal of Chemical Education. Vol. 77. 2000. 9-16. G. Lagaly & T. J. Pinnavaia.Clay Mineral-Polymer Nanocomposites, Applied Clay Science. Vol. 5. 1999. G. Gibbs. Changing lecturer's conceptions of teaching and learning through action research,. SRHE Press, 1995.

  1. Terahertz applications in cultural heritage: case studies

    Science.gov (United States)

    Giovannacci, D.; Martos-Levif, D.; Walker, G. C.; Menu, M.; Detalle, V.

    2013-11-01

    Terahertz (THz) spectroscopy and imaging is a non-destructive, non-contact, non-invasive technology emerging as a tool for the analysis of cultural heritage. THz Time Domain Spectroscopy (TDS) techniques have the ability to retrieve information from different layers within a stratified sample, that enable the identification of hidden sub-layers in the case of paints and mural paintings. In this paper, we present the THz TDS2 system developed in the European Commission's 7th Framework Program project CHARISMA [grant agreement no. 228330]. Bespoke single processing algorithms; including a deconvolution algorithm can be deployed to increase the resolution and the global performance of the system. The potential and impact of this work is demonstrated through two case studies of mural paintings, where the capability to reveal the stratigraphy of the artworks is demonstrated.

  2. Elegant solutions ten beautiful experiments in chemistry

    CERN Document Server

    Ball, Philip

    2005-01-01

    Devising and performing a scientific experiment is an art, and it is common to hear scientists talk about the 'beauty' of an experiment. What does this mean in chemistry, the experimental science par excellence? And what are the most beautiful chemical experiments of all time? This book offers ten suggestions for where beauty might reside in experimental chemistry. In some cases the beauty lies in the clarity of conception; sometimes it is a feature of the instrumental design. But for chemistry, there can also be a unique beauty in the way atoms are put together to make new molecules, substanc

  3. The Ten Plagues of Egypt

    Directory of Open Access Journals (Sweden)

    Roger S. Wotton

    2007-09-01

    Full Text Available The ten Plagues of Egypt described in the Bible were central to the liberation of the Jewish people from the oppression of the Egyptians. The succession of disasters demoralised the Egyptians and were seen as a victory for Jewish monotheistic beliefs. In this essay, natural explanations for most of the Plagues are proposed and a chronology of events is provided. Could the mythological explanation of these arguably natural phenomena still have a profound influence on the modern world?

  4. Case studies in using alternative sampling technologies

    International Nuclear Information System (INIS)

    Traditionally, site assessments for delineating petroleum hydrocarbon releases have been conducted in several phases. One way to improve the traditional assessment and remedial investigation methodology is to utilize alternative sampling techniques such as drive point sampling, combined with on-site field analytical methods. There are several drive point sampling technologies which have been used successfully in the past several years to collect both soil and groundwater samples. These drive point techniques include the Geoprobe trademark, Hydropunch trademark, Cone Penetrometer Testing (CPT) and KV trademark Sampling System. Utilized in combination with an on-site mobile laboratory equipped to conduct headspace analysis by EPA method 3810, these drive point sampling methods provide immediate, real-time data at a lower cost per data point. This paper presents three case studies in utilizing the Geoprobe trademark as an alternative sampling technology to gather both soil and groundwater data to delineate site contamination and provide for more informed, remedial solutions. In two of the cases (retail service stations), remediation by groundwater pump and treat had been on-going for several years with little remedial progress. The use of the alternative sampling technologies provided the needed information to expedite site clean-up. The remaining site is a petroleum refining facility where an active recovery system was planned. In this case, the data provided through the expedited assessment provided imperative design information

  5. LEADERSHIP STYLE-A CASE STUDY

    Directory of Open Access Journals (Sweden)

    Nitin B. Bhagwat

    2015-04-01

    Full Text Available The leadership is an art of getting things done through others to achieve the target. It is a style to put efforts of all people towards organizational goals. All these can be possible to a foresighted leader who will be regarded as the leader in the present LPG era. We find an ideal case of Asha Jain, the Director of Gnat Foundry Pvt. Ltd. She is leading 300 employees with her unique leadership style. She brought her unit out of worldwide recession (2008-2011, when some foundry units were in loss and few units were closed. Further, she established another unit named Yashaswi Foods and Products Pvt. Ltd. in such a critical situation in 2009 and also succeeded in it. The exclusive feature of this unit is 40 imprisoned women laboures out of 160. She started this unit with purely social responsibility under which she has tried to empower the effluent women’s. She started as a founder, a Rotary Club of Gargi, - a branch of Rotary Club in 2007. She is also a founder president of Jain International Women Organisation (2010. Aim of all this organization is to empower women – socially, economically as well as educationally. Considering the uniqueness of her working at industrial and social level, the researchers have decided to study the leadership style of Asha Jain as a case study. This study will bring out the unique features of successful leader which will be regarded as roadmap to others.

  6. Russian Media Educators: Case Studies Portraits

    Directory of Open Access Journals (Sweden)

    Alexander Fedorov

    2013-01-01

    Full Text Available This article is devoted to case studies of the media education works of some well knowns Russian media educators. The analysis of media educational work of the famous Russian media educators leads us to the conclusion that media education in Russia is developing, building on the synthesis of the aesthetic, socio-cultural, and practical concepts, with a focus on the development of media competence of the audience, mainly school and youth. The enthusiasts of media education, even devoid of substantial public support for its innovative projects, achieve significant and meaningful results.

  7. Wind to Hydrogen in California: Case Study

    Energy Technology Data Exchange (ETDEWEB)

    Antonia, O.; Saur, G.

    2012-08-01

    This analysis presents a case study in California for a large scale, standalone wind electrolysis site. This is a techno-economic analysis of the 40,000 kg/day renewable production of hydrogen and subsequent delivery by truck to a fueling station in the Los Angeles area. This quantity of hydrogen represents about 1% vehicle market penetration for a city such as Los Angeles (assuming 0.62 kg/day/vehicle and 0.69 vehicles/person) [8]. A wind site near the Mojave Desert was selected for proximity to the LA area where hydrogen refueling stations are already built.

  8. A Codesign Case Study in Computer Graphics

    DEFF Research Database (Denmark)

    Brage, Jens P.; Madsen, Jan

    The paper describes a codesign case study where a computer graphics application is examined with the intention to speed up its execution. The application is specified as a C program, and is characterized by the lack of a simple compute-intensive kernel. The hardware/software partitioning is based...... on information obtained from software profiling and the resulting design is validated through cosimulation. A locally developed interface model, Merlin, is used as the basis for co-simulation. The achieved speed-up is estimated based on an analysis of profile information....

  9. Reinforcement learning: Solving two case studies

    Science.gov (United States)

    Duarte, Ana Filipa; Silva, Pedro; dos Santos, Cristina Peixoto

    2012-09-01

    Reinforcement Learning algorithms offer interesting features for the control of autonomous systems, such as the ability to learn from direct interaction with the environment, and the use of a simple reward signalas opposed to the input-outputs pairsused in classic supervised learning. The reward signal indicates the success of failure of the actions executed by the agent in the environment. In this work, are described RL algorithmsapplied to two case studies: the Crawler robot and the widely known inverted pendulum. We explore RL capabilities to autonomously learn a basic locomotion pattern in the Crawler, andapproach the balancing problem of biped locomotion using the inverted pendulum.

  10. Case study: Wireless Sensor Networks Technology

    Directory of Open Access Journals (Sweden)

    Naveen Jain

    2013-03-01

    Full Text Available This paper present the history of research in sensor networks over the past decades, including two important programs of the Defense Advanced Research Projects Agency (DARPA, and the Distributed Sensor Networks (DSN and the Sensor Information Technology (SensIT programs. Technology trends that impact the development of sensor networks are reviewed, and new applications such as infrastructure security, habitat monitoring. The paper concludes by presenting some recent case studies results in sensor network algorithms, including localized algorithms and directed diffusion, distributed tracking in wireless ad hoc networks, and distributed classification using local agents.

  11. Case studies in Bayesian microbial risk assessments

    Directory of Open Access Journals (Sweden)

    Turner Joanne

    2009-12-01

    Full Text Available Abstract Background The quantification of uncertainty and variability is a key component of quantitative risk analysis. Recent advances in Bayesian statistics make it ideal for integrating multiple sources of information, of different types and quality, and providing a realistic estimate of the combined uncertainty in the final risk estimates. Methods We present two case studies related to foodborne microbial risks. In the first, we combine models to describe the sequence of events resulting in illness from consumption of milk contaminated with VTEC O157. We used Monte Carlo simulation to propagate uncertainty in some of the inputs to computer models describing the farm and pasteurisation process. Resulting simulated contamination levels were then assigned to consumption events from a dietary survey. Finally we accounted for uncertainty in the dose-response relationship and uncertainty due to limited incidence data to derive uncertainty about yearly incidences of illness in young children. Options for altering the risk were considered by running the model with different hypothetical policy-driven exposure scenarios. In the second case study we illustrate an efficient Bayesian sensitivity analysis for identifying the most important parameters of a complex computer code that simulated VTEC O157 prevalence within a managed dairy herd. This was carried out in 2 stages, first to screen out the unimportant inputs, then to perform a more detailed analysis on the remaining inputs. The method works by building a Bayesian statistical approximation to the computer code using a number of known code input/output pairs (training runs. Results We estimated that the expected total number of children aged 1.5-4.5 who become ill due to VTEC O157 in milk is 8.6 per year, with 95% uncertainty interval (0,11.5. The most extreme policy we considered was banning on-farm pasteurisation of milk, which reduced the estimate to 6.4 with 95% interval (0,11. In the second case study the effective number of inputs was reduced from 30 to 7 in the screening stage, and just 2 inputs were found to explain 82.8% of the output variance. A combined total of 500 runs of the computer code were used. Conclusion These case studies illustrate the use of Bayesian statistics to perform detailed uncertainty and sensitivity analyses, integrating multiple information sources in a way that is both rigorous and efficient.

  12. GRØD: A marketing case study

    OpenAIRE

    Nørager, Signe Lærke; Frimand-Meier, Benjamin; Laursen, Stine Vesterskov

    2013-01-01

    This project is a single in-depth case study of GRØD. Through interviews and theory it suggests how the branding strategy of GRØD must be to align with the vision of the company. Based hereon, a strategy of branding GRØD’s baby porridge is also sought to be found. The project concludes that the main point in GRØD’s vision is to generate a reinterpretation of porridge. However, this is not achieved to the intended extent, which is found to be caused by a missing definition of porridge from ...

  13. Privacy Aware Engineering: A Case Study

    Directory of Open Access Journals (Sweden)

    Xiaojun Ye

    2009-05-01

    Full Text Available Privacy is a complex social process that will persist in one form or another as a fundamental feature of software engineering. For successful privacy aware engineering, it is critical to guarantee the alignment and compliance among privacy artifacts emerging during software development process. In this paper, we propose a privacy compliance engineering flow in which we investigate the involved necessary privacy artifacts and discuss their alignment, refinement, and compliance verification. Within an exemplary case study, we identify the privacy artifacts introduced in the refinement process and analyze their compliance verification.

  14. The Danish National Case Study Report

    DEFF Research Database (Denmark)

    Brodersen, SØsser; JØrgensen, Michael SØgaard

    2003-01-01

    This report is the Danish case study report in the EU-financed project INTERACTS, which analyses experience and expectations to the interaction between NGOs, Science Shops and universities. The report analyses potentials and barriers to NGO’s and similar civil society groups’ use of research and science through co-operation with Science Shops as a mediator between universities and civil society. The Danish national case study report analyses three projects carried out through the Science Shops at DTU and RUC. One case is a co-operation between two DTU students and an NGO, whom is working towards promoting the use of bicycles. The project addresses how different actors perceive and understand the bicycles as technology, and how this is incorporated in traffic strategies and planning. A second case is a co-operation between two DTU students and a day-care centre, aiming at investigating storage facilities for organic food and the possibilities of local supply of organic food to the day-care centre. The third case is a co-operation between four RUC students and a local branch of a larger NGO working with nature and environment. This co-operation aims at investigating the pollution level in a village pond. Each case is described and reflected separately. A cross-analysis analyses the interactions among the involved actor group (clients, students, researchers, and Science Shops) discussing how the knowledge in the projects were developed and how the knowledge were used by the actors to try to gain impact on either research development or societal discourses. When civil society groups request assistance through the Science Shops, their need for knowledge and research is based on a need for scientific documentation of a certain topic, a need for enhancement of new knowledge and/or a need for development of new solutions and perspectives to problems. All three types of knowledge need is covered by one or more of the cases. The cases show that NGOs perceive research done through universities as neutral and creating more legitimacy than research done by the organisation itself. The cases show that all three NGO’s have used the results and findings to try influencing the societal discourses, and that the results and findings have helped two of the NGOs to gain influence. The analysis further shows that this influence seems to depend on the ability of the NGOs to build alliances with other actors. Knowledge in itself is not enough to get influence. The cases show that some students choose to conduct research through the Science Shops, because their research can be beneficial for someone, who does not have access to science and knowledge. Aspects like the possibility of gaining skills in co-operation and communication and knowledge about real life problems are also part of the students’ considerations when they chose to co-operate with civil society organisations through a Science Shop. Supervisors and scientists get engaged in Science Shop projects either because the topic of the investigation is within their own research area, because they find the topic interesting or because they see the project as a possibility to recruit students for later thesis projects or research projects. The challenges in the co-operation with civil society groups are to secure the scientific level in the projects, design the projects so it fits into the university schedule, without leaving out the time perspective of the clients, and secure the research is applicable for the clients and based on their need for knowledge. The case studies have shown different roles of a Science Shop. All Science Shops have a role as mediator between science and civil society by establishing contact between students, researchers and civil society organisations, but a Science Shop can also have a role as incubator in curricula and research development within the university based on the knowledge needs raised by civil society organisations. Through these activities a Science Shop might contribute to societal discourses, like when the Science Shop at DTU started addre

  15. A postural 'stressed' cerebral HMPAO case study

    International Nuclear Information System (INIS)

    Full text: This case study represents an example of the utility of postural hypoperfusion stressed HMPAO SPECT. An elderly woman of 78 with a long history of giddiness was referred to our laboratory for examination of possible cerebral ischaemia. She had recurrent dizzy episodes, sometimes posture related, over the past few years and had suffered several falls. Cerebral DSA revealed minimal disease. CT scans were reported as normal. Carotid duplex Doppler studies revealed bilateral plaque disease in the carotid bulbs extending to the origins of the ICAs which were not significant stenoses. Postural symptoms were induced by standing the patient up rapidly and HMPAO was administered at the same time. A SPECT scan of the brain was performed. Quantitative analysis showed a left to right decrease of 10.8% in the temporo-occipital area, 5.6% in the temporo-parietal area and 2.5% in the cerebellar and parietal areas. Images revealed moderately reduced tracer concentration in the left half of the cerebellum and the left occipital region extending as far forward as the temporo-parietal region A repeat HMPAO SPECT scan without stress was normal. This would appear to indicate reversible ischaemia in the left posterior region, and is consistent with the reported symptoms. This case illustrates the usefulness of HMPAO in the diagnosis of reversible cerebral ischaemia

  16. Case Study in Contemporary Educational Research: Conceptualization and Critique

    OpenAIRE

    Shen, Qi

    2009-01-01

    As one of important research methods, case study research has been used for many years across a variety of disciplines. This paper tries to review the principles and processes of case study. First, I would like to define case study according to its principles. Second, attentions will be put to the features and classification of the research of case study. Third, I intend to explain the process of case studies and case study methods. Fourth, I would review the strengths and weaknesses of case ...

  17. Commercializing Emerging Renewable Energy: A Case Study

    Directory of Open Access Journals (Sweden)

    Matti Lehtovaara

    2012-12-01

    Full Text Available A broad scientific consensus exists that the global climate is changing. The Earth’s surface temperature could rise significantly over the next few decades, leading to us witnessing an entirely new and unknown planet. Improved energy efficiency, decreasing use of fossil fuels and wide diffusion of various renewable energy sources are among the focal measures to limit global warming to a sustainable level. The objective of this study is to analyse how renewable energy, such as wind power and bioenergy, could be efficiently commercialized. The evaluation is based on a case study and expert analyses exploiting lateral and parallel thinking methods, and group decision support systems tools. The results reveal that some of the generated ideas are ready for implementation to commercialize renewable energy, whereas others still require technical and commercial development and improvements before maturity.

  18. Assessing proportionality in capital cases: a case study of Ohio

    OpenAIRE

    Berry III, William W.; Hoyle, Carolyn

    2011-01-01

    When the United States Supreme Court approved the reinstatement of the death penalty in the United States in 1976, it did so based on the promise of new safeguards against comparative excessiveness and relative disproportionality resulting from jury sentencing in capital cases. As Justice Stevens noted in 2008, one of these safeguards – meaningful appellate review of death sentences – is, in practice, non-existent. This thesis examines the use of this purported safeguard by the Ohio Supre...

  19. Ten Thousand Years of Solitude?

    International Nuclear Information System (INIS)

    This report documents the authors work as an expert team advising the US Department of Energy on modes of inadvertent intrusion over the next 10,000 years into the Waste Isolation Pilot Project (WIPP) nuclear waste repository. Credible types of potential future accidental intrusion into the WIPP are estimated as a basis for creating warning markers to prevent inadvertent intrusion. A six-step process is used to structure possible scenarios for such intrusion, and it is concluded that the probability of inadvertent intrusion into the WIPP repository over the next ten thousand years lies between one and twenty-five percent. 3 figs., 5 tabs

  20. Radiochemical purity of ten radiopharmaceuticals

    International Nuclear Information System (INIS)

    Ten radiopharmaceuticals in frequent clinical use were examined for their radiochemical purity. Thin-layer chromatography, paper chromatography and electrophoresis were used. The activity of the separated components was measured in a gamma sample changer. The assumed chemical identity of the radiochemical impurities was evaluated by comparing the results with data described in the literature. For all radiopharmaceuticals tested, the radiochemical purity was found to be not lower than the value claimed by the manufacturer and to be in accordance with the requirements of the European Pharmacopoeia as far as those pharmaceuticals are listed therein. (orig.)

  1. Ten questions on nuclear wastes

    International Nuclear Information System (INIS)

    The authors give explanations and answers to ten issues related to nuclear wastes: when a radioactive material becomes a waste, how radioactive wastes are classified and particularly nuclear wastes in France, what are the risks associated with radioactive wastes, whether the present management of radioactive wastes is well controlled in France, which wastes are raising actual problems and what are the solutions, whether amounts and radio-toxicity of wastes can be reduced, whether all long life radionuclides or part of them can be transmuted, whether geologic storage of final wastes is inescapable, whether radioactive material can be warehoused over long durations, and how the information on radioactive waste management is organised

  2. Ten Thousand Years of Solitude

    Energy Technology Data Exchange (ETDEWEB)

    Benford, G. (Los Alamos National Lab., NM (USA) California Univ., Irvine, CA (USA). Dept. of Physics); Kirkwood, C.W. (Los Alamos National Lab., NM (USA) Arizona State Univ., Tempe, AZ (USA). Coll. of Business Administration); Harry, O. (Los Alamos National Lab., NM (USA)); Pasqualetti, M.J. (Los Alamos National Lab., NM (USA) Arizona State Univ., Tempe, AZ (USA))

    1991-03-01

    This report documents the authors work as an expert team advising the US Department of Energy on modes of inadvertent intrusion over the next 10,000 years into the Waste Isolation Pilot Project (WIPP) nuclear waste repository. Credible types of potential future accidental intrusion into the WIPP are estimated as a basis for creating warning markers to prevent inadvertent intrusion. A six-step process is used to structure possible scenarios for such intrusion, and it is concluded that the probability of inadvertent intrusion into the WIPP repository over the next ten thousand years lies between one and twenty-five percent. 3 figs., 5 tabs.

  3. Oral lichen planus: study of 21 cases

    Scientific Electronic Library Online (English)

    Juliana Tristão, Werneck; Taiara de Oliveira, Costa; Christian Abreu, Stibich; Cristhiane Almeida, Leite; Eliane Pedra, Dias; Arley, Silva Junior.

    2015-06-01

    Full Text Available Abstract BACKGROUND: Lichen planus is considered to be the most common dermatological disease involving the oral mucosa. OBJECTIVE: To investigate the profile, clinical features, and the presence of dysplasia and candidiasis in patients with oral lichen planus. METHODS: A total of 21 patients were s [...] elected from 258 patients at risk for oral cancer development. RESULTS: Most of the patients were white (76,2%), female (66,6%), with mean age of 58.8 years. Eight were smokers and seven were alcohol consumers. The buccal mucosa was the most affected site, followed by the tongue and the gingiva. The reticular pattern was the most common appearance. Histopathology depicted dysplasia in nine cases and cytopathology was positive for Candida in eight cases in the first appointment. CONCLUSION: Our data are similar to the literature. Cytopathology was important for the diagnosis of candidiasis. Although the presence of dysplasia was verified, further studies are necessary to clarify the importance of this finding.

  4. Building Energy Information Systems: User Case Studies

    Energy Technology Data Exchange (ETDEWEB)

    Granderson, Jessica; Piette, Mary Ann; Ghatikar, Girish

    2010-03-22

    Measured energy performance data are essential to national efforts to improve building efficiency, as evidenced in recent benchmarking mandates, and in a growing body of work that indicates the value of permanent monitoring and energy information feedback. This paper presents case studies of energy information systems (EIS) at four enterprises and university campuses, focusing on the attained energy savings, and successes and challenges in technology use and integration. EIS are broadly defined as performance monitoring software, data acquisition hardware, and communication systems to store, analyze and display building energy information. Case investigations showed that the most common energy savings and instances of waste concerned scheduling errors, measurement and verification, and inefficient operations. Data quality is critical to effective EIS use, and is most challenging at the subsystem or component level, and with non-electric energy sources. Sophisticated prediction algorithms may not be well understood but can be applied quite effectively, and sites with custom benchmark models or metrics are more likely to perform analyses external to the EIS. Finally, resources and staffing were identified as a universal challenge, indicating a need to identify additional models of EIS use that extend beyond exclusive in-house use, to analysis services.

  5. Histopathological Study of 100 Cases of Vasculartumours

    Directory of Open Access Journals (Sweden)

    Kapuriya Dharmesh P

    2012-04-01

    Full Text Available Introduction: Vascular tumors show a broad variety of morphological appearances and cilinical behavior, the lesions are ranging from benign hemangiomas to intermediate lesion, which are locally aggressive, to highly malignant angiosarcoma. There is also the grey zone between true neoplasia and hamartoma, which makes difficulty in histopathological assessment. It is also important to decide the degree of malignancy as it can strongly influence the choice of treatment and prognosis. Methodology: Hundred cases of vascular tumors received at the department of pathology, medical college and SSG hospital, Baroda have been studied with a view to carrying out a histopathological analysis. Results: mploying modified Enzinger’s classification (2001 the break up of 100 cases was as follows : 37 – capillary hemangiomas, 26 – granuloma pyogenicum, 15 – cavernous hemangiomas, 07 – lymphangiomas, 04 – masson’s hemangiomas (papillary endothelial hyperplasia, 03 – epithelioid hemangiomas, 03 – lymphangiomas circumscriptum, 01 – cystic hygroma, 01 – spindle cell hemangioendothelioma, 01 – epithelioid hemangioendothelioma, 01 – glomus tumor, 01 – angiosarcoma. Majority of vascular tumors were benign, more common in children and young adults, most common sites were head and neck, which required only local surgical excision. Conclusion: Malignant and intermediate tumors formed as extremely small proportion of vascular tumors, which should be treated aggressively and closely followed up. [National J of Med Res 2012; 2(2.000: 152-155

  6. Logistics opportunity costs: A mining case study

    Directory of Open Access Journals (Sweden)

    Leani van Jaarsveld

    2013-05-01

    Full Text Available This study highlighted the importance of determining the impact that an ineffective mode of transport has on a firm’s transportation model and costs. The main focus of this study was to determine the logistics opportunity costs of using road transport within a mining firm. A case study approach was followed, as the investigation aimed to analyse a complex problem experienced by one company and present it in an easily understandable format. From the results of this study, it was apparent that the logistics opportunity costs associated with the mode of transport was substantial. This highlighted the need for firms to revise their choice of transport mode on a regular basis, as it has a major impact not only on their transportation costs, but also on their inventory holding and carbon emissions. The results also have implications for South Africa’s only freight railway, Transnet Freight Rail, which should not only focus on expanding its existing capacity, but also on improving its customer service delivery whilst containing tariff increases.

  7. Ten years of nuclear power

    International Nuclear Information System (INIS)

    Ten years have elapsed since the world's first nuclear power station began to supply electricity in Russia, and this in turn marked the end of a twelve year stage following the first controlled nuclear chain reaction at Chicago. These periods mark major stages in the development of atomic energy from the realm of abstract ideas to that of everyday industrial application. They followed a period of fundamental research and laboratory work, culminating in Enrico Fermi's demonstration of a system whereby the forces of the atom could be brought under control. Then it was necessary to find ways and means of using the chain reaction for practical purposes and on an industrial scale. And after this had been shown in 1954 to be technically possible, it had still to be developed into an economic process. The nuclear power station has proved itself from the technical and engineering standpoint. The third phase of development has been to bring it to the stage of being economically competitive with alternative sources of energy, and it would appear that we are now reaching that goal - though more slowly than had been envisaged ten years ago

  8. U-opportunities: why is ten equal to ten?

    Energy Technology Data Exchange (ETDEWEB)

    Julia, B. [Laboratoire de Physique Theorique, ENS, 75 - Paris (France)

    2002-07-01

    It seems to me at this time that two recent developments may permit fast progress on our way to understand the symmetry structure of toroidally (compactified and) reduced M-theory. The first indication of a (possibly) thin spot in the wall that prevents us from deriving a priori the U-duality symmetries of these models is to be found in the analysis of the hyperbolic billiards that control the chaotic tune evolution of (quasi)homogeneous anisotropic String. Supergravity or Einstein cosmologies near a spacelike singularity. What happens is that U--duality symmetry controls chaos via negative constant curvature. On the other hand it was noticed in 1982 that (symmetrizable) 'hyperbolic' Kac-Moody algebras have maximal rank ten, exactly like superstring models and that two of these four rank ten algebras matched physical theories. My second reason for optimism actually predates also the previous breakthrough, it was the discovery in 1998 of surprising superalgebras extending U-dualities to all (p + 1)-forms (associated to p-branes). They have a super-nonlinear sigma model structure similar to the symmetric space structure associated to 0-forms and they obey a universal self-duality field equation. As the set of forms is doubled to implement electric-magnetic duality, they obey a set of first order equations. More remains to be discovered but the beauty and subtlety of the structure cannot be a random emergence from chaos. In fact we shall explain how a third maximal rank hyperbolic algebra BE{sub 10} controls heterotic cosmological chaos and how as predicted Einstein's General Relativity fits into the general picture. (authors)

  9. Telepractice for pediatric Dysphagia: a case study.

    Science.gov (United States)

    Malandraki, Georgia A; Roth, Melissa; Sheppard, Justine Joan

    2014-01-01

    A closed-ended intensive pediatric swallowing telepractice program was developed and piloted in one pediatric patient with Opitz BBB/G and Asperger's Syndromes, oropharyngeal dysphagia and aerophagia. The present study is a case report. Outcome variables included behavioral, swallowing and quality of life variables, and were assessed at baseline and at the end of the four-week program. Selective variables were also assessed at a follow-up family interview four weeks post program completion. Over the four-week intervention period, the patient demonstrated substantial improvements in: oral acceptance of eating-related objects and a variety of foods (behavioral variable), timing of voluntary saliva swallows and aerophagia levels (swallowing variables) and quality of life. Follow-up interview analysis showed that most skills were retained or improved one-month post intervention. This intensive telepractice program proved to be feasible and effective for this pediatric patient with dysphagia. PMID:25945217

  10. Case study on industrial hazmat response teams.

    Science.gov (United States)

    Stephens, Shelly J

    2009-11-01

    In 1991, Amway formed an industrial hazardous materials (hazmat) team in order to respond quickly and efficiently to potential chemical spills. The company's goals were, and still are today, to protect employees, the environment and the local community, and to reduce the amount of resulting downtime. In 1991, the hazmat team was very well funded, enabling it to become a discrete department with its own management staff and nearly 100 hazmat volunteers. Due to changes in the business climate, Amway reorganised in 2000/01, and the hazmat team became part of a company that incorporated contract work into its scope. When this reorganisation occurred, the hazmat team was thoroughly re-evaluated. Its response function was maintained, but was systematically reinvented in the most lean way practicable while still meeting corporate goals. This case study represents Amway's hazmat team's journey through the evaluation process and subsequent reorganisation. PMID:20378491

  11. Case studies of attacks on communication networks

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Sin Bok; Han, Eon Suk [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1996-06-15

    Recently, as the computer hardware and communications are developed, the data exchange through inter-networking has been highlighted and the data is being recognized as a great asset. Most of the organizations, businesses and enterprises are open to the external world-computer communication networks, attention must be focused on the securities of the information infrastructure. A government organization has been developing 'Circuits Analyzers', and 'Hacker-Tracking Program' and is struggling to track down sneakers. In this report, we analyze the contents of the cases where the communication network has been invaded, from the past up until now in Korea. This report also contains the result of a study on E-mail security, for the protection of KAERI Integrated Management Information System under which utilizes the CALS concepts and web services. (Author)

  12. Case studies of attacks on communication networks

    International Nuclear Information System (INIS)

    Recently, as the computer hardware and communications are developed, the data exchange through inter-networking has been highlighted and the data is being recognized as a great asset. Most of the organizations, businesses and enterprises are open to the external world-computer communication networks, attention must be focused on the securities of the information infrastructure. A government organization has been developing 'Circuits Analyzers', and 'Hacker-Tracking Program' and is struggling to track down sneakers. In this report, we analyze the contents of the cases where the communication network has been invaded, from the past up until now in Korea. This report also contains the result of a study on E-mail security, for the protection of KAERI Integrated Management Information System under which utilizes the CALS concepts and web services. (Author)

  13. Corporate Government Strategy Development: A Case Study

    Directory of Open Access Journals (Sweden)

    Ali M. Al-Khouri

    2012-07-01

    Full Text Available In this article, we present a case study of one the successful government organisation strategy development exercises in the United Arab Emirates (UAE. The 2010-2013 strategy of Emirates Identity Authority (Emirates ID supported organisational development and allowed the Emirates ID to become a pioneer in its field of practice. Its strategy was among the reasons behind its selection and winning the Best Federal Authority Award in the 2012 UAE's federal Government Excellence Programme. This article attempts to describe the principles on which the organisational strategy was developed. It also outlines major accomplishments and the strategy's impact on overall organisational performance. We conclude that the new strategy helped the organisation become a successful example in the UAE and that further lessons can be learned from it, as we outline and discuss them to influence the field of practice.

  14. Robust control systems theory and case studies

    CERN Document Server

    Mackenroth, Uwe

    2004-01-01

    "Robust Control Systems" gives a self-contained introduction to modern Control Theory. It thus adds a textbook to the existing research-oriented literature on Robust Control. The author lays emphasis on the modern aspects of the design of controllers with prescribed performance and robustness properties. Different to the classical engineering approach, a rigorous mathematical treatment is essential for the full understanding and applicability of the modern methods such as H2 or H8 control or methods based on the structured singular value µ. Nevertheless, no prior knowledge of Control Theory is required as the classical fundamentals are introduced within the first few chapters. Subsequently a large part of the text provides elementary examples and industrial case studies, which are developed in full detail to show how modern methods can be applied to advanced problems. They make intensive use of MATLAB, especially the Control Systems Toolbox and the µ-Analysis and Synthesis Toolbox.

  15. Unraveling phonological conspiracies: A case study.

    Science.gov (United States)

    Dinnsen, Daniel A; Gierut, Judith A; Morrisette, Michele L; Rose, Darcy E

    2014-01-01

    This paper focuses on three seemingly unrelated error patterns in the sound system of a child with a phonological delay, Child 218 (male, age 4 years 6 months) and ascribes those error patterns to a larger conspiracy to eliminate fricatives from the phonetic inventory. Employing Optimality Theory for its advantages in characterizing conspiracies, our analysis offers a unified account of the observed repairs. The contextual restrictions on those repairs are, moreover, attributed to early developmental prominence effects, which are independently manifested in another error pattern involving rhotic consonants. Comparisons are made with a published case study involving a different implementation of the same conspiracy, the intent being to disambiguate the force behind certain error patterns. The clinical implications of the account are also considered. PMID:25000372

  16. Social Set Analysis : Four Demonstrative Case Studies

    DEFF Research Database (Denmark)

    Vatrapu, Ravi; Hussain, Abid

    2015-01-01

    This paper argues that the basic premise of Social Network Analysis (SNA) -- namely that social reality is constituted by dyadic relations and that social interactions are determined by structural properties of networks-- is neither necessary nor sufficient, for Big Social Data analytics of Facebook or Twitter data. However, there exist no other holistic computational social science approach beyond the relational sociology and graph theory of SNA. To address this limitation, this paper presents an alternative holistic approach to Big Social Data analytics called Social Set Analysis (SSA). Based on the sociology of associations and the mathematics of classical, fuzzy and rough set theories, this paper proposes a research program. The function of which is to design, develop and evaluate social set analytics in terms of fundamentally novel formal models, predictive methods and visual analytics tools for Big Social Data. Four demonstrative case studies, employing SSA, covering the range of descriptive, predictive, visual and prescriptive analytics are presented and briefly discussed.

  17. A case study in pathway knowledgebase verification

    Directory of Open Access Journals (Sweden)

    Shah Nigam H

    2006-04-01

    Full Text Available Abstract Background Biological databases and pathway knowledgebases are proliferating rapidly. We are developing software tools for computer-aided hypothesis design and evaluation, and we would like our tools to take advantage of the information stored in these repositories. But before we can reliably use a pathway knowledgebase as a data source, we need to proofread it to ensure that it can fully support computer-aided information integration and inference. Results We design a series of logical tests to detect potential problems we might encounter using a particular knowledgebase, the Reactome database, with a particular computer-aided hypothesis evaluation tool, HyBrow. We develop an explicit formal language from the language implicit in the Reactome data format and specify a logic to evaluate models expressed using this language. We use the formalism of finite model theory in this work. We then use this logic to formulate tests for desirable properties (such as completeness, consistency, and well-formedness for pathways stored in Reactome. We apply these tests to the publicly available Reactome releases (releases 10 through 14 and compare the results, which highlight Reactome's steady improvement in terms of decreasing inconsistencies. We also investigate and discuss Reactome's potential for supporting computer-aided inference tools. Conclusion The case study described in this work demonstrates that it is possible to use our model theory based approach to identify problems one might encounter using a knowledgebase to support hypothesis evaluation tools. The methodology we use is general and is in no way restricted to the specific knowledgebase employed in this case study. Future application of this methodology will enable us to compare pathway resources with respect to the generic properties such resources will need to possess if they are to support automated reasoning.

  18. Transcutaneous electric nerve stimulation in modulation of pain of tender points in syndrome fibromyalgia: case study

    Directory of Open Access Journals (Sweden)

    Isabel Mara Magalhães Roriz

    2008-01-01

    Full Text Available The Fibromyalgia is a syndrome of pain and chronic diffuse, characterized by the presence of at least 11 of 18 points called anatomically specific tender points, painful on palpation. As the pain diffuse the main symptom of fibromyalgia. The current treatment is focused mainly to the reduction of symptoms. Physiotherapy has an important role in improving the control of pain. This study aimed to verify the effectiveness of the main TENS of low frequency and high intensity in modulating pain of tender points of patients with fibromyalgia. For this was a case study of patient R. S. S., 38-year-old female carrier of the syndrome of fibromyalgia attended school in the clinic of the Faculty of Integrated Ceará (FISIOFIC. The patient was treated with the TENS-pain Acupuncture points in a total of twelve care and pain assessed before starting treatment and after three attendants. There was a significant reduction in pain intensity at 77.7% of the tender points in the second evaluation and 88.8% of the points in the other assessments. It was concluded that there was a reduction in the pain of tender points of the patient showing the analgesia promoted by TENS, so it should be used as a complementary treatment programs associated with other treatments and also served as a good technique to locate the tender points

  19. Landslide Economics: Concepts and Case Studies

    Science.gov (United States)

    Klose, Martin; Damm, Bodo

    2015-04-01

    Landslide economics is vital for fundamental understanding of landslide risk as dealing with two important topics: (i) impact assessment, either as damage statistics or cost modeling, and (ii) vulnerability assessment, i.e., the study of exposure, sensitivity, and resilience to landslide damage, ideally from both sociotechnical and financial perspective (e.g., Crovelli and Coe, 2009; Wills et al., 2014). Many aspects addressed in landslide economics have direct influence on landslide risk, including: (i) human activity is often a major causative factor of landslides, not only by predisposing or triggering them, but also as a result of inadequate (low-cost) landslide mitigation; (ii) the level of tolerable or acceptable risk, a measure driving a large part of landslide costs in industrialized countries, is highly variable, differing between individuals, public or private organizations, and societies, with its nature being to change over time; and (iii) decision makers are faced with finding the right balance in landslide mitigation, thus need to weight diverse geological and socioeconomic factors that control its effectiveness in both technical and financial terms (e.g., Klose et al., 2014a). A large part of the complexity in assessing landslide risk as measured by economic costs is due to unique problems in understanding of (i) what types of landslide damage affect human activity and infrastructure in which way, (ii) how society contributes and responds to various kinds of damage, and (iii) how landslide damage is valued in monetary terms. Landslide economics shows the potential to take account of these sociocultural factors to the benefit of risk analysis (e.g., Klose et al., 2014b). The present contribution introduces local and regional case studies in which different economic issues of landslide risk are highlighted using the example of public infrastructures in NW Germany. A special focus is on the following topics: (i) risk culture and created risk, (ii) disaster financing and budgetary burdens, and (iii) economic risk balancing in urban planning. The results of the conducted case studies are discussed with regard to method development for integrated assessment of landslide risk. References Crovelli, R.A., Coe, J.A., 2009. Probabilistic estimation of numbers and costs of future landslides in the San Francisco Bay region. Georisk 3, 206-223. Klose, M., Highland, L., Damm, B., Terhorst, B., 2014a. Estimation of direct landslide costs in industrialized countries: challenges, concepts, and case study. In: Sassa, K., Canuti, P., Yin, Y. (Eds.), Landslide Science for a Safer Geoenvironment. Volume 2: Methods of Landslide Studies. Springer, Berlin, pp. 661-667. Klose, M., Damm, B., Terhorst, B., 2014b. Landslide cost modeling for transportation infrastructures: a methodological approach. Landslides, DOI 10.1007/s10346-014-0481-1. Wills, C., Perez, F., Branum, D., 2014. New Method for Estimating Landslide Losses from Major Winter Storms in California and Application to the ARkStorm Scenario. Natural Hazards Review, DOI 10.1061/(ASCE)NH.1527-6996.0000142.

  20. Ten questions about systems biology

    DEFF Research Database (Denmark)

    Joyner, Michael J; Pedersen, Bente K

    understand how whole animals adapt to the real world. We argue that a lack of fluency in these concepts is a major stumbling block for what has been narrowly defined as 'systems biology' by some of its leading advocates. We also point out that it is a failure of regulation at multiple levels that causes many......In this paper we raise 'ten questions' broadly related to 'omics', the term systems biology, and why the new biology has failed to deliver major therapeutic advances for many common diseases, especially diabetes and cardiovascular disease. We argue that a fundamentally narrow and reductionist...... perspective about the contribution of genes and genetic variants to disease is a key reason 'omics' has failed to deliver the anticipated breakthroughs. We then point out the critical utility of key concepts from physiology like homeostasis, regulated systems and redundancy as major intellectual tools to...

  1. Odontoma: a retrospective study of 73 cases

    International Nuclear Information System (INIS)

    The purpose of the present study was to retrospectively evaluate the clinical findings and treatment results for impacted permanent teeth associated with odontomas. We retrospectively investigated 73 odontomas in 72 patients who visited Kyungpook National University Dental Hospital from April 2004 through November 2011. The study was performed using medical records, panoramic radiographs, and pathological reports. Data gathered included age, gender, location, chief complaints, effects on dentition, and treatment of odontoma and the impacted tooth associated with odontoma. Most compound odontomas (46.7%) were found in the second decade and complex odontomas were not related to age. Odontomas showed no gender predilection. Fifty-five cases (75.3%) of odontomas were detected on routine dental radiographs. Sixty percent of compound odontomas occurred in the canine area and 57.1% of complex odontomas in the molar areas. Impaction of permanent teeth (61.6%) was the most common complication on the adjacent teeth. Most odontomas (84.9%) were removed surgically and impacted permanent teeth were managed by surgical removal (53.2%), orthodontic treatment (25.5%), or surgical repositioning (6.4%). There was a statistically significant relation between age and preservation of the impacted permanent teeth associated with odontomas (p<0.01). Early detection and treatment of odontomas increase the possibility of preservation of the impacted tooth. Therefore, it would be suggested that periodic panoramic examination during the first and second decade of life might be beneficial for the early detection and better prognosis of odontomas.

  2. Antineutrino reactor safeguards - a case study

    CERN Document Server

    Christensen, Eric; Jaffke, Patrick

    2013-01-01

    Antineutrinos have been proposed as a means of reactor safeguards for more than 30 years and there has been impressive experimental progress in neutrino detection. In this paper we conduct, for the first time, a case study of the application of antineutrino safeguards to a real-world scenario - the North Korean nuclear crisis in 1994. We derive detection limits to a partial or full core discharge in 1989 based on actual IAEA safeguards access and find that two independent methods would have yielded positive evidence for a second core with very high confidence. To generalize our results, we provide detailed estimates for the sensitivity to the plutonium content of various types of reactors, including most types of plutonium production reactors, based on detailed reactor simulations. A key finding of this study is that a wide class of reactors with a thermal power of less than 0.1-1 GWth can be safeguarded achieving IAEA goals for quantitative sensitivity and timeliness with detectors right outside the reactor ...

  3. Odontoma: a retrospective study of 73 cases

    Energy Technology Data Exchange (ETDEWEB)

    An, Seo Young; An, Chang Hyeon; Choi, Karp Shik [School of Dentistry, Kyungpook National University, Daegu (Korea, Republic of)

    2012-06-15

    The purpose of the present study was to retrospectively evaluate the clinical findings and treatment results for impacted permanent teeth associated with odontomas. We retrospectively investigated 73 odontomas in 72 patients who visited Kyungpook National University Dental Hospital from April 2004 through November 2011. The study was performed using medical records, panoramic radiographs, and pathological reports. Data gathered included age, gender, location, chief complaints, effects on dentition, and treatment of odontoma and the impacted tooth associated with odontoma. Most compound odontomas (46.7%) were found in the second decade and complex odontomas were not related to age. Odontomas showed no gender predilection. Fifty-five cases (75.3%) of odontomas were detected on routine dental radiographs. Sixty percent of compound odontomas occurred in the canine area and 57.1% of complex odontomas in the molar areas. Impaction of permanent teeth (61.6%) was the most common complication on the adjacent teeth. Most odontomas (84.9%) were removed surgically and impacted permanent teeth were managed by surgical removal (53.2%), orthodontic treatment (25.5%), or surgical repositioning (6.4%). There was a statistically significant relation between age and preservation of the impacted permanent teeth associated with odontomas (p<0.01). Early detection and treatment of odontomas increase the possibility of preservation of the impacted tooth. Therefore, it would be suggested that periodic panoramic examination during the first and second decade of life might be beneficial for the early detection and better prognosis of odontomas.

  4. Families and healthy lifestyle: a case study

    Directory of Open Access Journals (Sweden)

    Camila Viana Lima

    2009-04-01

    Full Text Available A Federal University in Northeast of Brazil has been enlarging its activities on the five Campi. On its structure, one group stands out, the families who live around the academic unities of Porangabussu Campus. It aims to apprehend the social representations about the lifestyle of families with approach on their life activities. The case study, which was made with 30 families, happened from September 2006 to March 2007, and were used: semi-strutured interview; participative observation; photography of place's campus, and the working out of a testimony about the choice. It was used the Bardin Contents Analysis (1977 and the Robert Ott approach (1997 for photographs. The representations were organized in five categories, being the main representation, the lack of infra-structure and security on the campus. Based on the Ropper, Logan and Tierney Nursing Model (1990, it was found that all life activities were changed and the most affected were: safe environment, 23.9%; breath, work and distraction, with 13, 3% each, and sleep, 9.6%. About the photography's technique, the Structure of the Campus (33.7% and the aesthetics (37.6% were the most represented. The study allowed the knowledge of the reality experienced by families and the need for changes in this place.

  5. Go with the flow: A case study

    Energy Technology Data Exchange (ETDEWEB)

    Moran, J.A. [Alfred Hospital, Prahran, VIC (Australia)

    1998-03-01

    Full text: A 55-year-old female presented to the Alfred Emergency Department semi-conscious with frank rectal bleeding requiring blood volume replacement. Labelled red blood cell (RBC) scintigraphy was requested in order to locate the site of bleeding. In vitro labelling of 3 mL of patient``s blood was performed (PYP as a diluted tinning agent and 1 GBq of freshly eluted {sup 99}mTc) and suspended red cells were injected. Using a GE Starcam system with high resolution collimation, images were acquired for 30 seconds (2 s per frame) and thereafter continuously for 1. 5 hours (30 s per frame). During imaging, patient history became available revealing portal hypertension, oesophageal and anal varices due to myelofibrosis and previous cholecystectomy. Initial flow images showed bizarre abdominal collateral vessels. Accumulation of labelled RBC over 1.5 hours in the right upper quadrant indicated the hepatic flexure as the site of bleeding. The initial flow study showing major porto-systemic collateral vessels indicated that therapeutic embolisation via angiography would be life threatening. The patient underwent emergency hemicolectomy and has been bleed-free to date. In this case, delayed RBC scintigraphy accurately located the haemorrhage site. However, the initial flow study demonstrating major vessel collateral flow was crucial in contraindicating angiographic embolisation. Surgery was then the only therapeutic option.

  6. Bilingual education in Slovakia: A Case Study

    Directory of Open Access Journals (Sweden)

    Silvia Pokriv?áková

    2013-06-01

    Full Text Available Bilingual education is one of the areas in contemporary education that brings out some important controversies (philosophical, conceptual, sociological, political, economical, etc. and thus calls for extensive and intensive debate. Bilingual education in Europe (and here the European Union countries are meant has gained a very different status, due to the general European policy of developing language diversity and promoting “European plurilingualism and multilingualism”. In Slovakia, one of the younger members of the EU, bilingual education became an extraordinarily popular instrument for the fulfilment of this task.  Since the specifically defined topic of bilingual education and its current status in Slovakia has not been studied and systematically reviewed yet, the research presented in this paper was designed as a single-phenomenon revelatory case study investigating seven research areas: reflection of bilingual education in school legislation and state pedagogical documents, purposes of bilingual education in Slovakia, its organization (levels and types of schools, foreign languages incorporated, teachers, structure of bilingual schools curricula, types of bilingual education applied at Slovak bilingual schools, and how bilingual education is both reflected in and saturated by the latest research findings. The conclusions presented in the paper were collected from multiple sources: state curriculum, statistical data published by the Slovak Ministry of Education or its partner institutions, international treaties on establishing and supporting bilingual sections of schools, bilingual schools curricula, interviews with school directors, teachers, and learners, direct observations at bilingual schools, research studies and research reports, etc. In the conclusion, bilingual education in Slovakia is identified as a unique, dynamically developing system which is both significantly shaped by the foreign language education policy promoted by the European Council (1995 as well as bears some specific characteristics, determined by its unique historical, political, and socio-cultural contexts. The paper includes partial results of the research project KEGA 036UKF-4/2013 Creating university textbooks and multimedia courses for a new study program funded by the Ministry of Education of the Slovak Republic.

  7. Ten years of progress in the Hokkaido birth cohort study on environment and children’s health: cohort profile—updated 2013

    OpenAIRE

    Kishi, Reiko; Kobayashi, Sachiko; Ikeno, Tamiko; Araki, Atsuko; Miyashita, Chihiro; Itoh, Sachiko; Sasaki, Seiko; Okada, Emiko; Kobayashi, Sumitaka; Kashino, Ikuko; Itoh, Kumiko; Nakajima, Sonomi

    2013-01-01

    The Hokkaido Study on Environment and Children’s Health is an ongoing cohort study that began in 2002. The study consists of two prospective birth cohorts, the Sapporo cohort (n = 514) and the Hokkaido large-scale cohort (n = 20,940). The primary goals of this study are to first examine the potential negative effects of perinatal environmental chemical exposures on birth outcomes, including congenital malformations and growth retardation; second, to evaluate the development of allergies, infe...

  8. Anxiety and IBS revisited: ten years later

    OpenAIRE

    Stefan-Lucian Popa; Dan Lucian Dumitrascu

    2015-01-01

    BACKGROUND AND AIM:   Irritable bowel syndrome (IBS) has been associated with high prevalence of psychological and psychiatric disorders. However, the association between IBS and each of its subtypes ( diarrhea IBS-D, constipation IBS-C, mixed IBS-M) with anxiety, still remains unclear. The purpose of this study was to perform a comparative analysis, of the association between anxiety and IBS on a period of ten years.METHODS: PubMed was searched for studies analyzing IBS and anxiety, publishe...

  9. Ten out of ten for LHC decapole magnets

    CERN Multimedia

    2001-01-01

    CERN's Albert Ijspeert (left) and Avinash Puntambekar of the Indian CAT laboratory with the ten Indian decapole magnets on the test bench. Tests will be carried out by the LHC-MTA group. A batch of 10 superconducting decapole magnets for the LHC has just arrived at CERN from India. These will be used to correct for slight imperfections in the dipole magnets that will steer proton beams around CERN's new accelerator. All magnets have slight imperfections in the fields they produce, and in the LHC dipoles these will be corrected for using sextupoles and decapoles. The sextupoles were the first LHC magnets to be given the production green-light following successful tests of pre-series magnets last year (Bulletin 21/2000, 22 May 2000). Now it is the turn of pre-series decapoles to go on trial at CERN. Of the LHC's 1232 dipole magnets, half will use sextupole correctors only and the other half will use both sextupoles and decapoles. That means that a total of 616 pairs of decapoles are needed. Like the sextupole...

  10. The Undergraduate Case Research Study Model

    Science.gov (United States)

    Vega, Gina

    2010-01-01

    Student-written cases are powerful pedagogical tools that can lead to improved understanding of business situations, more informed analysis, emphasis on reflection, and clearer expository writing, all of which are critical skills for business students. Cases provide an opportunity for students to enjoy an active learning experience and derive the…

  11. Case Study: Camptocormia, a Rare Conversion Disorder.

    Science.gov (United States)

    Rajmohan, Velayudhan; Thomas, Biju; Sreekumar, Kumaran

    2004-01-01

    Camptocormia is a condition characterized by severe frontal flexion of the spinal cord and knees, with passive drooping of both arms. It occurs as a form of conversion disorder. Some cases are associated with behavioral problems. A case of camptocormia of 2-year duration in a south Indian adolescent girl with oppositional defiant disorder and…

  12. Genetic Predisposition to Long-Term Nondiabetic Deteriorations in Glucose Homeostasis: Ten-Year Follow-Up of the GLACIER Study

    OpenAIRE

    Renström, F.; Shungin, Dmitry; Johansson, I; Florez, JC; Hallmans, G.; Hu, FB; Franks, Paul

    2011-01-01

    Objective: To assess whether recently discovered genetic loci associated with hyperglycemia also predict long-term changes in glycemic traits. Research Design and Methods: Sixteen fasting glucose-raising loci were genotyped in middle-aged adults from the Gene x Lifestyle interactions And Complex traits Involved in Elevated disease Risk (GLACIER) Study, a population-based prospective cohort study from northern Sweden. Genotypes were tested for association with baseline fasting and 2-h postchal...

  13. Suicide attempts and related factors in patients admitted to a general hospital: a ten-year cross-sectional study (1997-2007)

    OpenAIRE

    Lantes-Louzao Sara; Martínez-Sande Gonzalo; García-Fernández Jorge; Iglesias-Gil-de-Bernabé Fernando; Gómez-Pardiñas Sonia M; Pita-Fernández Salvador; Alberdi-Sudupe Jesús; Pértega-Díaz Sonia

    2011-01-01

    Abstract Background Suicide and suicide attempts represent a severe problem for public health services. The aim of this study is to determine the socio-demographic and psychopathological variables associated with suicide attempts in the population admitted to a General Hospital. Methods An observational-descriptive study of patients admitted to the A Coruña University Hospital (Spain) during the period 1997-2007, assessed by the Consultation and Liaison Psychiatric Unit. We include n = 5,234 ...

  14. Assessing greenhouse gas emissions from Swedish Production : A study on the possibility to reduce the greenhouse gas emissions from the ten most valuable production categories in Sweden

    OpenAIRE

    Richter, Vide

    2015-01-01

    Industrialised and developing countries face an urgent challenge to decouple economic growth and greenhouse gas emissions. The aim of this study is to investigate where the largest potentials are to the Swedish industry decrease greenhouse gas emissions without increasing their costs. To limit the scope of the study is made by assessing the 10 largest categories of production by value sold in Sweden. The objectives are to investigate: (a) which the 10 largest categories are; (b) how much the ...

  15. Deficiencies of effectiveness of intervention studies in veterinary medicine: a cross-sectional survey of ten leading veterinary and medical journals

    Science.gov (United States)

    Meursinge Reynders, Reint

    2016-01-01

    The validity of studies that assess the effectiveness of an intervention (EoI) depends on variables such as the type of study design, the quality of their methodology, and the participants enrolled. Five leading veterinary journals and 5 leading human medical journals were hand-searched for EoI studies for the year 2013. We assessed (1) the prevalence of randomized controlled trials (RCTs) among EoI studies, (2) the type of participants enrolled, and (3) the methodological quality of the selected studies. Of 1707 eligible articles, 590 were EoI articles and 435 RCTs. Random allocation to the intervention was performed in 52% (114/219; 95%CI:45.2–58.8%) of veterinary EoI articles, against 87% (321/371; 82.5–89.7%) of human EoI articles (adjusted OR:9.2; 3.4–24.8). Veterinary RCTs were smaller (median: 26 animals versus 465 humans) and less likely to enroll real patients, compared with human RCTs (OR:331; 45–2441). Only 2% of the veterinary RCTs, versus 77% of the human RCTs, reported power calculations, primary outcomes, random sequence generation, allocation concealment and estimation methods. Currently, internal and external validity of veterinary EoI studies is limited compared to human medical ones. To address these issues, veterinary interventional research needs to improve its methodology, increase the number of published RCTs and enroll real clinical patients.

  16. Guidelines for Conducting Positivist Case Study Research in Information Systems

    Directory of Open Access Journals (Sweden)

    Graeme Shanks

    2002-11-01

    Full Text Available The case study research approach is widely used in a number of different ways within the information systems community. This paper focuses on positivist, deductive case study research in information systems. It provides clear definitions of important concepts in positivist case study research and illustrates these with an example research study. A critical analysis of the conduct and outcomes of two recently published positivist case studies is reported. One is a multiple case study that validated concepts in a framework for viewpoint development in requirements definition. The other is a single case study that examined the role of social enablers in enterprise resource planning systems implementation. A number of guidelines for successfully undertaking positivist case study research are identified including developing a clear understanding of key concepts and assumptions within the positivist paradigm; providing clear and unambiguous definitions of the units and interactions when using any theory; carefully defining the boundary of the theory used in the case study; using hypotheses rather than propositions in the empirical testing of theory; using fuzzy or probabilistic propositions in recognising that reality can never be perfectly known; selecting case studies carefully, particularly single case studies; and recognising that generalisation from positivist, single case studies is inherently different from generalisation from single experiments. When properly undertaken, positivist, deductive case study research is a valuable research approach for information systems researchers, particularly when used within pluralist research programs that use a number of different research approaches from different paradigms.

  17. New case study guidelines: a call to arms for practitioners.

    OpenAIRE

    McDowall, A.; Short, E.

    2012-01-01

    This article outlines our new journal guidelines for case studies to encourage practice-based submissions. We first outline how case studies have similarities with and may differ from case studies in psychology and Human Resource Management research. This leads us to propose 10 succinct guidelines for writing up case study submissions, covering formatting in terms of length and referencing, the need to cover both process and outcome(s) and as well as ethical ramifications and declarations of ...

  18. Comparative economic analysis: Anaerobic digester case study

    International Nuclear Information System (INIS)

    An economic guide is developed to assess the value of anaerobic digesters used on dairy farms. Two varieties of anaerobic digesters, a conventional mixed-tank mesophilic and an innovative earthen psychrophilic, are comparatively evaluated using a cost-effectiveness index. The two case study examples are also evaluated using three other investment merit statistics: simple payback period, net present value, and internal rate of return. Life-cycle savings are estimated for both varieties, with sensitivities considered for investment risk. The conclusion is that an earthen psychrophilic digester can have a significant economic advantage over a mixed-tank mesophilic digester because of lower capital cost and reduced operation and maintenance expenses. Because of this economic advantage, additional projects are being conducted in North Carolina to increase the rate of biogas utilization. The initial step includes using biogas for milk cooling at the dairy farm where the existing psychrophilic digester is located. Further, a new project is being initiated for electricity production with thermal reclaim at a swine operation

  19. VINCRISTINE INDUCED NEUROTOXICITY: STUDY OF 75 CASES

    Directory of Open Access Journals (Sweden)

    M.T. Arzanian

    2009-08-01

    Full Text Available ObjectiveConcern for side-effects of therapy related to treatment of childhood malignancies is becoming an increasingly important topic. In this study, we evaluated extent of vincristine (VCR induced neurotoxicity in a group of children who underwent chemotherapy, with VCR being part of the regimen.Materials & MethodsIn this investigation, for 75 children (54% boys, 46% girls, aged between 1 to 14 (mean 6.5±4.3 years, serial weekly neurological examinations were performed; of the 75, 70 had acute lymphoblastic leukemia and 5 Wilm's tumor. All patients were on a chemotherapy protocol of at least 4 consecutive VCR (1.5mg/m2 injections.ResultsDecreased deep tendons reflexes were seen in the Achilles reflex in 78%, and the patellar reflex in 53% of patients. Muscle weakness was found in 70% of patients, being mild in 76% of them. Four  percent of patients showed severe weakness. Petosis, jaw pain, hoarseness, abdominal pain and constipation were seen in 15%, 6%, 12%, 12% and 12% respectively. Paresthesia was observed in 32 of 52 patients, over 4 years old. No cases of foot drop, urinary retention or facial nerve palsy were seen in this patient group.ConclusionChildren on usual doses of vincristine regimen may have neuropathic side effects but most of these side effects are mild and not troublesome.Key words: Vincristine, neuropathy, neurotoxicity, side effect

  20. High Penetration Photovoltaic Case Study Report

    Energy Technology Data Exchange (ETDEWEB)

    Bank, J.; Mather, B.; Keller, J.; Coddington, M.

    2013-01-01

    Technical concerns with integrating higher penetrations of photovoltaic (PV) systems include grid stability, voltage regulation, power quality (voltage rise, sags, flicker, and frequency fluctuations), and protection and coordination. The current utility grid was designed to accommodate power flows from the central generation source to the transmission system and eventually to the distribution feeders. At the distribution level, the system was designed to carry power from the substation toward the load. Renewable distributed generation, particularly solar PV, provides power at the distribution level challenging this classical paradigm. As these resources become more commonplace the nature of the distribution network and its operation is changing to handle power flow in both directions. This report is focused on large PV installations in which penetration is significantly greater than 15% of maximum daytime feeder load. These case studies are intended to demonstrate success stories with integration of large PV plants at the distribution level as well as some of the solutions used by the utility to ensure safe, reliable operation of both the PV system and the distribution network.

  1. Visualization Case Study: Eyjafjallajökull Ash (Invited)

    Science.gov (United States)

    Simmon, R.

    2010-12-01

    Although data visualization is a powerful tool in Earth science, the resulting imagery is often complex and difficult to interpret for non-experts. Students, journalists, web site visitors, or museum attendees often have difficulty understanding some of the imagery scientists create, particularly false-color imagery and data-driven maps. Many visualizations are designed for data exploration or peer communication, and often follow discipline conventions or are constrained by software defaults. Different techniques are necessary for communication with a broad audience. Data visualization combines ideas from cognitive science, graphic design, and cartography, and applies them to the challenge of presenting data clearly. Visualizers at NASA's Earth Observatory web site (earthobservatory.nasa.gov) use these techniques to craft remote sensing imagery for interested but non-expert readers. Images range from natural-color satellite images and multivariate maps to illustrations of abstract concepts. I will use imagery of the eruption of Iceland's Eyjafjallajökull volcano as a case study, showing specific applications of general design techniques. By using color carefully (including contextual data), precisely aligning disparate data sets, and highlighting important features, we crafted an image that clearly conveys the complex vertical and horizontal distribution of airborne ash.

  2. Bayesian inference in physics: case studies

    Science.gov (United States)

    Dose, V.

    2003-09-01

    This report describes the Bayesian approach to probability theory with emphasis on the application to the evaluation of experimental data. A brief summary of Bayesian principles is given, with a discussion of concepts, terminology and pitfalls. The step from Bayesian principles to data processing involves major numerical efforts. We address the presently employed procedures of numerical integration, which are mainly based on the Monte Carlo method. The case studies include examples from electron spectroscopies, plasma physics, ion beam analysis and mass spectrometry. Bayesian solutions to the ubiquitous problem of spectrum restoration are presented and advantages and limitations are discussed. Parameter estimation within the Bayesian framework is shown to allow for the incorporation of expert knowledge which in turn allows the treatment of under-determined problems which are inaccessible by the traditional maximum likelihood method. A unique and extremely valuable feature of Bayesian theory is the model comparison option. Bayesian model comparison rests on Ockham's razor which limits the complexity of a model to the amount necessary to explain the data without fitting noise. Finally we deal with the treatment of inconsistent data. They arise frequently in experimental work either from incorrect estimation of the errors associated with a measurement or alternatively from distortions of the measurement signal by some unrecognized spurious source. Bayesian data analysis sometimes meets with spectacular success. However, the approach cannot do wonders, but it does result in optimal robust inferences on the basis of all available and explicitly declared information.

  3. Environmental injustice: case studies from the South

    International Nuclear Information System (INIS)

    We selected three case studies to illustrate environmental injustice issues in the South. These examples relate to migrant agricultural workers, the maquiladora industry and artisanal mining, while reviewing some of the major mechanisms involved, e.g. multinational corporations, the development of free trade zones, multilateral free trade agreements and the export of hazards. A series of strategies are discussed in order to address environmental injustice and health disparities that exist on a global scale. Some of the recommendations involve policy initiatives; others, such as research and mentorship, fall within the traditional domain of public health practice. In this paper, special attention is given to concerned environmental and occupational health professionals using evidence-based data for advocacy. For lasting changes to be made, however, stronger institutions and legislation are required. Those who have the 'right to know' about environmental injustice issues include communities of concern, workers' representatives and lawyers. Government officials and company officials may eventually work on the basis of conflict resolution, compensation and remediation, to quote some examples. Systematic approaches to protect both the environment and public health must be updated

  4. Environmental injustice: case studies from the South

    Science.gov (United States)

    Cifuentes, Enrique; Frumkin, Howard

    2007-10-01

    We selected three case studies to illustrate environmental injustice issues in the South. These examples relate to migrant agricultural workers, the maquiladora industry and artisanal mining, while reviewing some of the major mechanisms involved, e.g. multinational corporations, the development of free trade zones, multilateral free trade agreements and the export of hazards. A series of strategies are discussed in order to address environmental injustice and health disparities that exist on a global scale. Some of the recommendations involve policy initiatives; others, such as research and mentorship, fall within the traditional domain of public health practice. In this paper, special attention is given to concerned environmental and occupational health professionals using evidence-based data for advocacy. For lasting changes to be made, however, stronger institutions and legislation are required. Those who have the 'right to know' about environmental injustice issues include communities of concern, workers' representatives and lawyers. Government officials and company officials may eventually work on the basis of conflict resolution, compensation and remediation, to quote some examples. Systematic approaches to protect both the environment and public health must be updated.

  5. Replicated Rejuvenated Services. A Case Study

    Directory of Open Access Journals (Sweden)

    Rodica Tirtea

    2009-05-01

    Full Text Available During testing, verification and validationof complex software it is difficult to detect all faults. Itis hard to anticipate run-time complex interactions inorder to design reactive fault tolerance mechanismscovering all situations. As such, proactive faulttolerance techniques are required. Softwarerejuvenation is a proactive fault tolerance techniquedesign to bring the system to a clear state whendegradation of functionality is detected. As defined atbeginning, software rejuvenation is considered only fora system (an application.Due to increase in quality-of-service requirements, theuser is the part assessing the availability of servicesdelivered. The user does not care about the systemdelivering the service. We defined replicatedrejuvenated services for modeling rejuvenation whenwe consider the availability of the services delivered.The model proposed considers the services delivered by an application, where replication can be used to improve availability.A case study is presented in this paper. The original model for software rejuvenation is compared with the model proposed for replicated rejuvenated services. Cost analysis is presented for both cost of downtime and const of unavailability.

  6. CFD analysis for road vehicles - case study

    Directory of Open Access Journals (Sweden)

    Eugen Mihai NEGRUS

    2011-09-01

    Full Text Available This is a case study on the influence of the lower part of road vehicles on the global drag characteristics. Reducing overall drag by redesigning the lower part of the road vehicles has a potential of almost 20% in the overall drag breakdown, mainly due to the viscous effects and the fluidic interaction of the flow under the car with the typical bluff body flow pattern behind the vehicle. A special parameterization is proposed for the global shape of the sedan car, with respect to the lower part of the body, taking into account most of the specificities of the system. For such a complex interaction, CFD analysis is probably the only efficient tool in order to assess specific design parameterization of a generic car shape. Building on the credibility of such instruments is one of the major goals of this paper. Also, with respect to a target sedan car configuration, examples of successful design strategies are presented. Based on the CFD results, possible strategies to be used in order to reduce viscous drag and global drag characteristics are proposed.

  7. Jazz improvisers’ shared understanding: A case study

    Directory of Open Access Journals (Sweden)

    MichaelF.Schober

    2014-08-01

    Full Text Available To what extent and in what arenas do collaborating musicians need to understand what they are doing in the same way? Two experienced jazz musicians who had never previously played together played three improvisations on a jazz standard (“It Could Happen to You” on either side of a visual barrier. They were then immediately interviewed separately about the performances, their musical intentions, and their judgments of their partner’s musical intentions, both from memory and prompted with the audiorecordings of the performances. Statements from both (audiorecorded interviews as well as statements from an expert listener were extracted and anonymized. Two months later, the performers listened to the recordings and rated the extent to which they endorsed each statement. Performers endorsed statements they themselves had generated more often than statements by their performing partner and the expert listener; their overall level of agreement with each other was greater than chance but moderate to low, with disagreements about the quality of one of the performances and about who was responsible for it. The quality of the performances combined with the disparities in agreement suggest that, at least in this case study, fully shared understanding of what happened is not essential for successful improvisation. The fact that the performers endorsed an expert listener’s statements more than their partner’s argues against a simple notion that performers’ interpretations are always privileged relative to an outsider’s.

  8. DEINDUSTRIALIZATION AND UNDERDEVELOPMENT. CASE STUDY: VALEA JIULUI

    Directory of Open Access Journals (Sweden)

    Mihnea PREOTESI

    2014-01-01

    Full Text Available The paper is based on the preliminary results of the research project "Deindustrialization and under-development in the Romanian Transition. Individual/Collective Strategies and Reply Policies. Case study: Valea Jiului", that will be done within the POSDRU project "Plural and interdisciplinary in doctoral and post-doctoral programs". This paper intends to analyze the complex relation between economic development, social development and modernization. The basic hypothesis of the proposed analysis is that the economic development is not an irreversible process not even when it leads to social development as part of a modernizing program. Valea Jiului represents an example of how the economic and social development built on weak basis, become unsustainable. The collapse of this weak basis initiated after 1989 when the economy and the society changed and after a transition period produced a major negative social impact started with the restructuring of the mining. In less than 10 months, the number of the miners was reduced to half and the reduction continued. Today in Valea Jiului is only 15 % of the number of employees in 1989. The social effects of the mining restructuring were at communitarian level the underdevelopment, return to pre-modern occupations like the subsistence agriculture. A good example that will be deeply analyzed in this paper is the town Aninoasa, the first Romanian town in insolvency since 2013.

  9. Case studies: Redevelopment of former industrial sites

    International Nuclear Information System (INIS)

    This paper presents the case studies of the redevelopment of two sites: Herr's Island, located in the Allegheny River in Pittsburgh, Pennsylvania and the Union Pacific Resources Company's site located near the Port of Long Beach in Wilmington, California. The common goal in cleaning up both sites is the transformation of environmentally unsound property into flourishing residential and commercial use. Herr's Island site has included a petroleum refinery, an asphalt plant, pipe mills, a meat packing plant, and a transformer dismantling facility. A small portion of the island was investigated as part of a Phase 2 audit. The investigation identified contamination in the southern portion of the island with maximum polynuclear aromatic hydrocarbon (PAH) and polychlorinated biphenyl (PCB) concentrations in soils at 40 and 200 parts per million (ppm), respectively. The Union Pacific Resources Company (UPRC) site, located in Wilmington, California, is situated within a 600-acre oil field production area. A phased remedial investigation (RI) of the site was initiated in 1991 pursuant to a consent agreement between UPRC and the California Department of Toxic Substances Control (DTSC). The RI identified the presence of volatile organic compounds (VOCs), semi-volatile organic compounds, chlorinated pesticides, PAHs, PCBs and metals at various concentrations throughout the soils. VOCs and metals were also detected in the groundwater. In particular, arsenic, benzene, vinyl chloride, and mercury were encountered at concentration levels at, or slightly above, drinking water standards in a few samples

  10. Refugee Problem in Europe – Case Studies

    Directory of Open Access Journals (Sweden)

    Esztella Varga

    2015-11-01

    Full Text Available The European refugee problem has grown dramatically in the last few months, putting a considerable amount of pressure on the European countries. Not only are they facing migrants from North Africa, but from the Middle East as well.In March 2011 the Arab Spring has reached Syria, causing a huge number of Syrians to flee their country and seek asylum in Turkey, and possibly going further to the EU. The refugees who fled Syria as well as those who are leaving North Africa (mostly the failed state of Libya are aiming to reach European soil, but Italy, Greece or Turkey is not ready to handle the amount of refugees. The cooperation of the Mediterranean countries and Europe has not been able to slow down the flow of refugees, and the Mediterranean and Aegean seas have become dangerous routes for the desperate migrants who attempt the sea-crossing. In my analysis I would like to highlight the role of the so-called elements of ‘soft power’ in the way of dealing with the refugee problem. According to my hypothesis, the issue can’t be successfully addressed using only the means of the ‘soft power’. No real solution for the crisis has been offered yet, and I would like to give case studies of the different ways of dealing with the problem – inside (Greece, Italy and outside (Turkey of the European Union.

  11. Bayesian inference in physics: case studies

    International Nuclear Information System (INIS)

    This report describes the Bayesian approach to probability theory with emphasis on the application to the evaluation of experimental data. A brief summary of Bayesian principles is given, with a discussion of concepts, terminology and pitfalls. The step from Bayesian principles to data processing involves major numerical efforts. We address the presently employed procedures of numerical integration, which are mainly based on the Monte Carlo method. The case studies include examples from electron spectroscopies, plasma physics, ion beam analysis and mass spectrometry. Bayesian solutions to the ubiquitous problem of spectrum restoration are presented and advantages and limitations are discussed. Parameter estimation within the Bayesian framework is shown to allow for the incorporation of expert knowledge which in turn allows the treatment of under-determined problems which are inaccessible by the traditional maximum likelihood method. A unique and extremely valuable feature of Bayesian theory is the model comparison option. Bayesian model comparison rests on Ockham's razor which limits the complexity of a model to the amount necessary to explain the data without fitting noise. Finally we deal with the treatment of inconsistent data. They arise frequently in experimental work either from incorrect estimation of the errors associated with a measurement or alternatively from distortions of the measurement signal by some unrecognized spurious source. Bayesian data analysis sometimes meets with spectacular success. However, the approach cannot do wonders, but it does result in optimal robust inferences on the basis of all available and explicitly declared information

  12. Business and Legal Case Genre Networks: Two Case Studies

    Science.gov (United States)

    Uhrig, Karl

    2012-01-01

    The framework of genre systems (Bazerman, 1994; Bhatia, 2004; Swales, 2004) offers an opportunity to illuminate the ways in which students enculturate into their disciplinary cultures (Berkenkotter & Huckin, 1995). To explore the ways in which genre chains are constructed through engagement in specific tasks, this study investigates two…

  13. The student experience of Foundation Degrees: a case study of a cohort in a Foundation Degree in Educational Administration

    OpenAIRE

    Thelwell, Helen Wendy

    2008-01-01

    This thesis is the result of a qualitative case study of a group of ten part-time, mature, non-traditional learners enrolled on a Foundation Degree. The thesis identifies how students think, communicate with one another and manage the learning processes. It explores the attitudes of students who are a new type of cohort entering Higher Education. The thesis commences by identifying entry barriers to Higher Education and how these were overcome. Despite earlier failures, stud...

  14. Large-Scale Participation: A Case Study of a Participatory Approach to Developing a New Public Library

    DEFF Research Database (Denmark)

    Dalsgaard, Peter; Eriksson, Eva

    2013-01-01

    In this paper, we present a case study of a participatory project that focuses on interaction in large-scale design, namely, the development of the new Urban Mediaspace Aarhus. This project, which has been under way for ten years, embodies a series of issues that arise when participatory design approaches are applied to large-scale, IT-oriented projects. At the same time, it highlights the issues public knowledge institutions face, when interactive technologies challenge their fundamental roles ...

  15. Engaged Learning and Change through Undergraduate Research: A Case Study of the Heart of Gold Community Empowerment Project

    OpenAIRE

    David William Robinson; J. Laureen Styles; Nichola Evernden; Kassandra Kirkham

    2013-01-01

    The focus of this paper is to describe a best-practice undergraduate research-involved case study of the Heart of Gold Rural Community Empowerment Project (HG) that has demonstrated significant gains in social and economic capital over the last ten years. The HG is an international community-university research alliance between the Farm and Agro-tourism Association of Los Santos (FAALS) cooperative in Costa Rica and Vancouver Island University (VIU) in Canada that uses cooperative inquiry met...

  16. Case Study Research in Software Engineering Guidelines and Examples

    CERN Document Server

    Runeson, Per; Rainer, Austen; Regnell, Bjorn

    2012-01-01

    Based on their own experiences of in-depth case studies of software projects in international corporations, in this book the authors present detailed practical guidelines on the preparation, conduct, design and reporting of case studies of software engineering.  This is the first software engineering specific book on the case study research method.

  17. Arsenic Removal: Adsorptive Media and Coagulation/Filtration Case Studies

    Science.gov (United States)

    This presentation provides information on the results of three case studies from USEPA arsenic demonstration program. The first case study presented is on the Rimrock, AZ project that used an adsorptive media technology (E33 media) to remove arsenic. The second case study is on...

  18. The shortcomings of computer-aided measurement of migration for the prediction of failure of three forms of acetabular fixation by survival analysis and migration study to ten years.

    Science.gov (United States)

    Scott, G; Nakagawa, S; Orhan, Z; Freeman, M

    2006-01-01

    We studied, to ten years, migration by vertical displacement and angular change using a digitizer and standard radiographs and survival of three methods of acetabular fixation in primary hip replacement. Two implants were uncemented metal-backed components, one version of which was hydroxyapatite-coated. Both types had 28 mm polyethylene inserts. The third type was a cemented all-polyethylene cup with a 28 mm internal diameter. All cups articulated with a Freeman neck-retaining stem. The purpose was to see if the early migration data predicted the long-term outcome and could be used to forecast implants that would fail for the purpose of pre-market assessment. No statistical differences were found between the groups in the parameters studied. At the threshold accuracies of our migration measurements (three millimetres and three degrees) at three years, we could not identify components that would subsequently fail. However, migration less than these threshold values and the absence of radiolucent lines were strongly associated with implant survival at ten years. Our system was insufficiently accurate for pre-market surveillance.; PMID:19219800

  19. Effect of rearing media on the susceptibility of Tribolium casteneum (Herbst) to gamma radiation : Studies with insects reared on the same medium for ten generations

    International Nuclear Information System (INIS)

    Studies on the radiation susceptibility of Tribolium castaneum (Herbst) reared on the medium upto 10th generation revealed that the order of relative susceptibility of T. castaneum for different food media was Bengal gram >barley>maize>wheat>jowar. However, LD50 values to radiation for insects bred on Bengal gram, barley and maize for 10 generations were found to be considerably higher than those obtained with insects reared on the same medium for one generation only. (author)

  20. Effect of nationwide selenium supplementation in Finland on selenium status in children with juvenile rheumatoid arthritis. A ten-year follow-up study.

    Science.gov (United States)

    Wang, W C; Näntö, V; Mäkelä, A L; Mäkelä, P

    1995-03-01

    A study was performed on the effect of increased selenium intake on the serum selenium level of 212 children with juvenile rheumatoid arthritis (JRA) and of 214 controls in a follow-up study during the Finnish nationwide selenium fertilization programme, which was started in 1984. The mean serum level of selenium increased from 0.90 mumol l-1 in 1985 to 1.56 mumol l-1 in 1990 in the children with JRA. The corresponding selenium levels in the controls were 0.87 mumol l-1 in 1985 and 1.33 mumol l-1 in 1990. Boys had slightly higher selenium levels in all the age groups among the patients and the controls. During the entire 10-year observation period, the patients with JRA had slightly higher mean levels of selenium than the controls. The age of the children did not have any significant effect on the selenium level in either group. The present study shows that the main factor affecting the serum level of selenium was the dietary intake of selenium both in patients and in healthy controls. PMID:7741263

  1. Environmental noise exposure, early biological risk and mental health in nine to ten year old children: a cross-sectional field study

    Directory of Open Access Journals (Sweden)

    Stansfeld Stephen A

    2011-05-01

    Full Text Available Abstract Background Previous research suggests that children born prematurely or with a low birth weight are more vulnerable to the mental health effects of ambient neighbourhood noise; predominantly road and rail noise, at home. This study used data from the Road Traffic and Aircraft Noise Exposure and Children's Cognition and Health (RANCH study to see if this finding extends to aircraft and road traffic noise at school. Methods Children and their parents from schools around three European airports were selected to represent a range of aircraft and road traffic noise exposure levels. Birth weight and gestation period were merged to create a dichotomous variable assessing 'early biological risk'. Mental health was assessed using the Strengths and Difficulties Questionnaire (SDQ. Complete data were available for 1900 primary school children. Results Children who were 'at risk' (i.e. low birth weight or premature birth were rated as having more conduct problems and emotional symptoms and poorer overall mental health than children not at risk. However, there was no interaction between aircraft or road traffic noise exposure at school and early biological risk. Conclusions Data from the RANCH study suggests that children with early biological risk are not more vulnerable to the effects of aircraft or road traffic noise at school on mental health than children without this risk; however they are more likely to have mental ill-health.

  2. Pipeline corridors through wetlands - summary of seventeen plant-community studies at ten wetland crossings. Topical report, February 1990--August 1994

    Energy Technology Data Exchange (ETDEWEB)

    Van Dyke, G.D. [Argonne National Lab., IL (United States)]|[Trinity Christian College, Palos Heights, IL (United States); Shem, L.M.; Wilkey, P.L.; Zimmerman, R.E.; Alsum, S.K. [Argonne National Lab., IL (United States)

    1994-12-01

    As part of the Gas Research Institute Wetland Corridors Program, Argonne National Laboratory conducted field studies on 10 wetland crossings located in six states to document impacts of natural gas pipeline rights-of-way (ROWS) on 15 wetland plant communities. This study is unique in the number, range, ages, and variety of wetland crossings surveyed and compared. Vegetation data and recorded observations were analyzed to reveal patterns associated with age, installation technology, maintenance practices, and wetland type. This report summarizes the findings of this study. Results revealed that ROWs of pipelines installed according to recent wetland regulations rapidly revegetated with dense and diverse plant communities. The ROW plant communities were similar to those in the adjacent natural areas in species richness, wetland indicator values, and percentages of native species. The ROW plant communities developed from naturally available propagules without fertilization, liming, or artificial seeding. ROWs contributed to increased habitat and plant species diversity in the wetland. There was little evidence that they degrade the wetland by providing avenues for the spread of invasive and normative plant species. Most impacts are temporal in nature, decreasing rapidly during the first several years and more slowly thereafter to the extent permitted by maintenance and other ROW activities.

  3. Jane: A Case Study in Anorexia Nervosa.

    Science.gov (United States)

    Willingham, Barbara

    1988-01-01

    The article reports the case history of a 15-year-old Australian girl with anorexia nervosa. Information is also given on prevalence, causes, definitions, and treatments including hospitalization, co-therapy, psychotherapy, behavior modification, family therapy, and counseling. (DB)

  4. Structured Controversy: A Case Study Strategy.

    Science.gov (United States)

    Herreid, Clyde Freeman

    1996-01-01

    Introduces a dynamic form of the case instruction method that involves debate and compromise. Discusses two versions of structured controversy and presents an example of structured controversy that involves the use of DNA fingerprinting in forensic medicine. (JRH)

  5. TIMWE : Born Global Firm : case study

    OpenAIRE

    Marques, Frederico José Castro Reis

    2013-01-01

    TIMWE is the Portuguese based company chosen to illustrate and serve as background to support the creation of a teaching case in Strategy, exploring the internationalization of a real company and the challenges undertaken by the process of being a born global firm, followed by a Teaching Note that can be used as a tool to help solving the case. TIMWE is a Portuguese owned company, founded in 2002, that offers mobile monetization solutions and services (entertainment, marketing and money) t...

  6. Study of Kidney Repair Mechanisms of Corn Silk (Zea mays L. Hair-Binahong (Anredera cordifolia (Ten. Steenis Leaves Combination in Rat Model of Kidney Failure

    Directory of Open Access Journals (Sweden)

    Levina Ferdiana Adiwibowo

    2013-01-01

    Full Text Available Earlier studies from our laboratory have indicated renal function improving action of corn silk and binahong in gentamicin-piroxicam induced kidney failure. This study was aimed to determine the effects of combination of cornsilk and binahong extracts on kidney failure model in rat and the effects of the extract combination on oxidative stress. Rats were divided into the positive control group, the group treated with 75 mg kg-1 of corn silk, the group treated with 100 mg kg-1 b.wt. of binahong, two groups treated with graded doses of combination of corn silk and binahong and the negative control group. Serum creatinine, urea, organ-to-body weight ratio of the kidney (kidney index and renal histology were assessed to determine renal function. Meanwhile, the activities of lipid peroxidation, catalase and Superoxide Dismutase (SOD were measured to analyse oxidative stress level. Administration of combination of the extracts at half dose resulted in marked depletion of serum creatinine and urea which was comparable to the results in corn silk-and binahong-treated groups. In addition, the extract combination was shown to reduce kidney index compared to that of the positive control group. The combination was further revealed to reduce renal damage histologically. Administration of the extract combination was demonstrated to attenuate kidney oxidative stress as shown by the reduction in lipid peroxidation and the increased activity of antioxidant enzymes, such as catalase and SOD. Taken together, results of this study suggest that corn silk in combination with binahong possesses renal function improving activity which is slightly better compared to the activity of each extract alone. The results further indicate that reduction of oxidative stress by each extract as well as their combination might be beneficial to the repair of renal damage.

  7. Ten-year health service use outcomes in a population-based cohort of 21,000 injured adults: the Manitoba injury outcome study.

    OpenAIRE

    C.M. Cameron; Purdie, D. M.; Kliewer, E V; McClure, R. J.

    2006-01-01

    OBJECTIVE: To quantify long-term health service use (HSU) following non-fatal injury in adults. METHODS: A retrospective, population-based, matched cohort study identified an inception cohort (1988-91) of injured people who had been hospitalized (ICD-9-CM 800-995) aged 18-64 years (n = 21 032) and a matched non-injured comparison group (n = 21 032) from linked administrative data from Manitoba, Canada. HSU data (on hospitalizations, cumulative length of stay, physician claims and placements i...

  8. Mobile and Social: Ten Best Practices for Designing Mobile Applications

    Directory of Open Access Journals (Sweden)

    Liviu LICA

    2010-01-01

    Full Text Available This paper gives ten best practices for designing mobile applications that have social-networking functions. The need for such an approach is given by the rapid growth in impor-tance of both social networks and mobile applications. In order to make it easy to follow where the best practices come from, the paper starts with a look at why social networks are more than just a buzz word and at how the field of mobile applications is evolving. It also shows how and why the two fields go together so well. To further make the point, there is a case study of four interesting mobile applications that are textbooks examples of successful applications. The best practices are based on research done for this article and on the extensive knowledge of the author.

  9. Urban street networks: a comparative analysis of ten European cities

    CERN Document Server

    Strano, Emanuele; Cardillo, Alessio; Costa, Luciano Da Fontoura; Porta, Sergio; Latora, Vito

    2012-01-01

    We compare the structural properties of the street networks of ten different European cities using their primal representation. We investigate the properties of the geometry of the networks and a set of centrality measures highlighting differences and similarities among cases. In particular, we found that cities share structural similarities due to their quasi planarity but that there are also several distinctive geometrical proprieties. A Principal Component Analysis is also performed on the distributions of centralities and their respective moments, which is used to find distinctive characteristics by which we can classify cities into families. We believe that, beyond the improvement of the empirical knowledge on streets network proprieties, our findings can open new perspectives in the scientific relation between city planning and complex networks, stimulating the debate on the effectiveness of the set of knowledge that statistical physics can contribute for city planning and urban morphology studies.

  10. Herb-Induced Liver Injury in the Berlin Case-Control Surveillance Study.

    Science.gov (United States)

    Douros, Antonios; Bronder, Elisabeth; Andersohn, Frank; Klimpel, Andreas; Kreutz, Reinhold; Garbe, Edeltraut; Bolbrinker, Juliane

    2015-01-01

    Herb-induced liver injury (HILI) has recently attracted attention due to increasing reports of hepatotoxicity associated with use of phytotherapeutics. Here, we present data on HILI from the Berlin Case-Control Surveillance Study. The study was initiated in 2000 to investigate the serious toxicity of drugs including herbal medicines. Potential cases of liver injury were ascertained in more than 180 Departments of all 51 Berlin hospitals from October 2002 to December 2011. Drug or herb intake was assessed through a standardized face-to-face interview. Drug or herbal aetiology was assessed based on the updated Council for International Organizations of Medical Sciences scale. In ten of all 198 cases of hepatotoxicity included in the study, herbal aetiology was assessed as probable (once ayurvedic herb) or possible (Valeriana five times, Mentha piperita once, Pelargonium sidoides once, Hypericum perforatum once, Eucalyptus globulus once). Mean age was 56.4 ± 9.7 years, and the predominant pattern of liver injury was hepatocellular. No cases of acute liver failure or death were observed. This case series corroborates known risks for ayurvedic herbs, supports the suspected association between Valeriana use and liver injury, and indicates a hepatotoxic potential for herbs such as Pelargonium sidoides, Hypericum perforatum or Mentha piperita that were rarely associated with liver injury before. However, given that possible causality does not prove clinical significance, further studies in this field are needed. PMID:26784183

  11. Real or Illusory? Case Studies on the Public Perception of Environmental Health Risks in the North West of England

    Directory of Open Access Journals (Sweden)

    Richard Jarvis

    2010-03-01

    Full Text Available Applied research in a public health setting seeks to provide professionals with insights and knowledge into complex environmental issues to guide actions that reduce inequalities and improve health. We describe ten environmental case studies that explore the public perception of health risk. We employed logical analysis of components of each case study and comparative information to generate new evidence. The findings highlight how concerns about environmental issues measurably affect people’s wellbeing and led to the development of new understanding about the benefits of taking an earlier and more inclusive approach to risk communication that can now be tested further.

  12. Case Study on social software in distributed working environments

    OpenAIRE

    Kieslinger, Barbara; Hofer, Margit; Cao, Yiwei; Ehms, Karsten; Fiedler, Sebastian; Kairamo, Anna-Kaarina; Klamma, Ralf; Krause, Beate; Kravcik, Milos; Ryyppö, Tommi; Spaniol, Marc; Stumme, Gerd; Wild, Fridolin

    2007-01-01

    This document outlines four different case studies on the use of Social Software in distributed working environments. While two case studies focus on the corporate world, two other case studies look at the use of Social Software in academic workplaces. The concluding remarks identify some common benefits as well as issues with the use of Social Software and to derive some further research challenges from the different cases. The findings for future research need to be directed towards strateg...

  13. Brazilian oil spills chemical characterization : case studies

    International Nuclear Information System (INIS)

    The Petrobras Research Centre has been active in responding to some significant oil spills in Brazil in the past decade. The centre has characterized spilled oil, monitored the affected ecosystems and determined the fate of oil in the environment. This paper described the use of some advanced chemical analytical techniques used in Brazilian oil spill studies to determine fractions and individual petroleum hydrocarbons in water, groundwater, sediment, sand, fish and the spilled oil itself. Some of the most recent oil spill cases were discussed in terms of chemical characterization of the spilled oil and the environmental samples from different matrices of the affected ecosystems for determining the fate of the oil in the environment and to assess environmental damage. In particular, methods such as gas chromatography/flame ionization detector, P and T/GC/PID and gas chromatography/mass spectrometry have been used to examine crude and fuel oil spills in Guanabara Bay, Barigui and Iguassu Rivers, and the Sao Sebastiao Channel. The chemical analytical methods are used to determine total petroleum hydrocarbons, n-alkanes, isoprenoids, unresolved complex mixtures, volatile monoaromatic compounds such as BTEX (benzene, toluene, ethylbenzene and xylenes), as well as parent and alkylated homologues polycyclic aromatic hydrocarbons (PAH) and terpanes and steranes. Acute ecotoxicity data for water and sediment samples was also included. It was determined that with certain limitations, PAH ratios can help determine the origin of hydrocarbons as being either petrogenic or pyrolytic. However, alkylated PAH homologues and parent compounds such as dibenzothiophene and perylene give more precise interpretation of the data. 30 refs., 9 tabs., 11 figs

  14. Brazilian oil spills chemical characterization : case studies

    Energy Technology Data Exchange (ETDEWEB)

    Meniconi, M.F.G.; Gabardo, I.T.; Carneiro, M.E.R. [Petrobras Cenpes, Rio de Janeiro (Brazil); Barbanti, S.M. [Pontificia Universidad Catolica Foundation, Rio de Janeiro (Brazil); Silva, G.C.; Massone, C.G. [Gorceix Foundation, Rio de Janeiro (Brazil)

    2002-07-01

    The Petrobras Research Centre has been active in responding to some significant oil spills in Brazil in the past decade. The centre has characterized spilled oil, monitored the affected ecosystems and determined the fate of oil in the environment. This paper described the use of some advanced chemical analytical techniques used in Brazilian oil spill studies to determine fractions and individual petroleum hydrocarbons in water, groundwater, sediment, sand, fish and the spilled oil itself. Some of the most recent oil spill cases were discussed in terms of chemical characterization of the spilled oil and the environmental samples from different matrices of the affected ecosystems for determining the fate of the oil in the environment and to assess environmental damage. In particular, methods such as gas chromatography/flame ionization detector, P and T/GC/PID and gas chromatography/mass spectrometry have been used to examine crude and fuel oil spills in Guanabara Bay, Barigui and Iguassu Rivers, and the Sao Sebastiao Channel. The chemical analytical methods are used to determine total petroleum hydrocarbons, n-alkanes, isoprenoids, unresolved complex mixtures, volatile monoaromatic compounds such as BTEX (benzene, toluene, ethylbenzene and xylenes), as well as parent and alkylated homologues polycyclic aromatic hydrocarbons (PAH) and terpanes and steranes. Acute ecotoxicity data for water and sediment samples was also included. It was determined that with certain limitations, PAH ratios can help determine the origin of hydrocarbons as being either petrogenic or pyrolytic. However, alkylated PAH homologues and parent compounds such as dibenzothiophene and perylene give more precise interpretation of the data. 30 refs., 9 tabs., 11 figs.

  15. What Superintendents Should Do to Position Their Districts to be Prepared for the Changing Nature of Technology in the Next Ten Years: A Delphi Study

    Science.gov (United States)

    Ainsworth, Ean

    Over the past twenty years, schools and districts have been faced with the challenge of integrating technology into their classroom instruction. The rapid rate of evolution that technology changes has placed new burdens on school and district leaders to plan meaningful professional development, create and develop effective policy, and focus on school and district culture. In the coming years, the changing nature of technology is not expected to slow down and most certainly will accelerate. The purpose of this Delphi study was to identify what K-12 superintendents should do to position their districts to be prepared for the changing nature of technology in the next 10 years. The expert panel for this study was comprised of K-12 superintendents from eight Northern California counties. This Delphi study consisted of three rounds. In Round 1, the expert panel identified 74 strategies that superintendents should do to position their districts to be prepared for the changing nature of technology in the next 10 years. Those items were thematically categorized and where then narrowed down into a list of 30 strategies in preparation for Round 2. During Round 2, the expert panel rated the 30 strategies on the level of influence it would have on preparing districts for the changing nature of technology in the next 10 years using a 6-point Likert scale. In Round 3, each panel member was given the mean rating for each item as well as their own ratings for each item. Each panel member was then given the opportunity to change their ratings to the Round 2 survey. The expert panel identified four strategies which had the highest combined mean and median scores as well as an interquartile range of less than two. Each of the strategies from Round 2 and 3 had a mean score of four or higher. However, consensus was reached on four strategies which were rated with the highest combined mean and median scores. The four highest rated strategies were represented by three categories: culture, professional development, and investment in infrastructure.

  16. Suicide attempts and related factors in patients admitted to a general hospital: a ten-year cross-sectional study (1997-2007

    Directory of Open Access Journals (Sweden)

    Lantes-Louzao Sara

    2011-03-01

    Full Text Available Abstract Background Suicide and suicide attempts represent a severe problem for public health services. The aim of this study is to determine the socio-demographic and psychopathological variables associated with suicide attempts in the population admitted to a General Hospital. Methods An observational-descriptive study of patients admitted to the A Coruña University Hospital (Spain during the period 1997-2007, assessed by the Consultation and Liaison Psychiatric Unit. We include n = 5,234 admissions from 4,509 patients. Among these admissions, n = 361 (6.9% were subsequent to a suicide attempt. Admissions arising from a suicide attempt were compared with admissions occurring due to other reasons. Multivariate generalised estimating equation logistic regression models were used to examine factors associated with suicide attempts. Results Adjusting by age, gender, educational level, cohabitation status, being employed or unemployed, the psychiatric diagnosis at the time of the interview and the information on previous suicide attempts, we found that the variables associated with the risk of a suicide attempt were: age, psychiatric diagnosis and previous suicide attempts. The risk of suicide attempts decreases with age (OR = 0.969. Psychiatric diagnosis was associated with a higher risk of suicide attempts, with the highest risk being found for Mood or Affective Disorders (OR = 7.49, followed by Personality Disorders (OR = 7.31, and Schizophrenia and Other Psychotic Disorders (OR = 5.03. The strongest single predictive factor for suicide attempts was a prior history of attempts (OR = 23.63. Conclusions Age, psychopathological diagnosis and previous suicide attempts are determinants of suicide attempts.

  17. Mathematical modelling with case studies using Maple and Matlab

    CERN Document Server

    Barnes, B

    2014-01-01

    Introduction to Mathematical ModelingMathematical models An overview of the book Some modeling approaches Modeling for decision makingCompartmental Models Introduction Exponential decay and radioactivity Case study: detecting art forgeries Case study: Pacific rats colonize New Zealand Lake pollution models Case study: Lake Burley Griffin Drug assimilation into the blood Case study: dull, dizzy, or dead? Cascades of compartments First-order linear DEs Equilibrium points and stability Case study: money, money, money makes the world go aroundModels of Single PopulationsExponential growth Density-

  18. Exeresis and Brachytherapy as Salvage Treatment for Local Recurrence After Conservative Treatment for Breast Cancer: Results of a Ten-Year Pilot Study

    International Nuclear Information System (INIS)

    Purpose: To analyze the long-term results of a pilot study assessing excision and brachytherapy as salvage treatment for local recurrence after conservative treatment of breast cancer. Methods and Materials: Between December 1990 and March 2001, 36 patients with breast-only recurrence less than 3 cm in diameter after conservative treatment for Stage I or II breast carcinoma were treated with local excision followed by high-dose rate brachytherapy implants (30 Gy in 12 fractions over a period of 5 days). No patient was lost to follow-up. Special attention was paid to local, regional, or distant recurrences; survival; cosmesis; and early and late side effects. Results: All patients completed treatment. During follow-up (range, 1-13 years), 8 patients presented metastases (2 regional and 6 distant) as their first site of failure, 1 had a differed local recurrence, and 1 died of the disease. Actuarial results at 10 years were as follows: local control, 89.4%; disease-free survival, 64.4%; and survival, 96.7%. Cosmetic results were satisfactory in 90.4%. No patient had Grade 3 or 4 early or late complications. Of the 11 patients followed up for at least 10 years, all but 1 still had their breast in place at the 10-year stage. Conclusions: High-dose rate brachytherapy is a safe, effective treatment for small-size, low-risk local recurrence after local excision in conservatively treated patients. The dose of 30 Gy of high-dose rate brachytherapy (12 fractions over a period of 5 days twice daily) was well tolerated. The excellent results support the use of breast preservation as salvage treatment in selected patients with local recurrence after conservative treatment for breast cancer.

  19. Ten-year health service use outcomes in a population-based cohort of 21 000 injured adults: the Manitoba Injury Outcome Study

    Directory of Open Access Journals (Sweden)

    CM Cameron

    2006-10-01

    Full Text Available OBJECTIVE: To quantify long-term health service use (HSU following non-fatal injury in adults. METHODS: A retrospective, population-based, matched cohort study identified an inception cohort (1988-91 of injured people who had been hospitalized (ICD-9-CM 800-995 aged 18-64 years (n = 21 032 and a matched non-injured comparison group (n = 21 032 from linked administrative data from Manitoba, Canada. HSU data (on hospitalizations, cumulative length of stay, physician claims and placements in extended care services were obtained for the 12 months before and 10 years after the injury. Negative binomial and Poisson regressions were used to quantify associations between injury and long-term HSU. FINDINGS: Statistically significant differences in the rates of HSU existed between the injured and non-injured cohorts for the pre-injury year and every year of the follow-up period. After controlling for pre-injury HSU, the attributable risk percentage indicated that 38.7% of all post-injury hospitalizations (n = 25 183, 68.9% of all years spent in hospital (n = 1031, 21.9% of physician claims (n = 269 318 and 77.1% of the care home placements (n = 189 in the injured cohort could be attributed to being injured. CONCLUSION: Many people who survive the initial period following injury, face long periods of inpatient care (and frequent readmissions, high levels of contact with physicians and an increased risk of premature placement in institutional care. Population estimates of the burden of injury could be refined by including long-term non-fatal health consequences and controlling for the effect of pre-injury comorbidity.

  20. Reading and writing difficulties in adolescence and later risk of welfare dependence. A ten year follow-up, the HUNT Study, Norway

    Directory of Open Access Journals (Sweden)

    Holmen Turid L

    2011-09-01

    Full Text Available Abstract Background Welfare dependence and low work participation among young people have raised concern in many European countries. Reading and writing difficulties (RWD might make young people vulnerable to work integration problems and welfare dependence through negative influences on education and health. Our main objective of this study was to examine if RWD in adolescence affected the risk of welfare dependence in young adulthood. Methods Baseline information on self-reported RWD, health and family was obtained for 8950 school-attending adolescents in Nord-Trøndelag County, Norway, participating in the Young-HUNT1 survey, 1995-97. All individuals were linked to biological parents to identify siblings and parental education from national registers. Welfare dependence was assessed by the reception of social benefits (medical and economic from the national social insurance database (1998-2007. Only long-term benefits (> 180 days were included. Results The adolescents who reported RWD at baseline were more likely to receive medical or social benefits during follow-up compared with those who did not report RWD. In girls with RWD, the adjusted 5-year risk (at age 24 to 28 for receiving medical benefits was 0.20 (95% confidence interval 0.14-0.26, compared with 0.11 (0.09-0.12 in girls without RWD. In boys the corresponding risks were 0.13 (0.09-0.17 and 0.08 (0.07-0.09. Conclusions The associations between RWD in adolescence and welfare dependence later in life suggest that increased attention should be paid to these problems when discussing the public health aspects of work integration, since there might be a potential for prevention.

  1. Using Clinical Gait Case Studies to Enhance Learning in Biomechanics

    Science.gov (United States)

    Chester, Victoria

    2011-01-01

    Clinical case studies facilitate the development of clinical reasoning strategies through knowledge and integration of the basic sciences. Case studies have been shown to be more effective in developing problem-solving abilities than the traditional lecture format. To enhance the learning experiences of students in biomechanics, clinical case…

  2. A case study of a Cuban government institution

    International Nuclear Information System (INIS)

    The aim of this contribution is to present a case study on the partial implementation of a knowledge management system in an institution. In this case the knowledge management has been directed toward the best performance of the organization. The tool used in case study can be implemented at any institution, including institutions of nuclear or radiological profiles. (author)

  3. Sabbatical Leave: A Case Study of Professional Growth and Development.

    Science.gov (United States)

    Holmes, Julie A.

    This paper explores the results of a case study of a 6-month sabbatical taken to complete a master's degree program. It reports the case of a practicing elementary school teacher with 9 years of teaching experience. This intrinsic, reflexive case study was undertaken to help the participant better understand the meaning and effect of the…

  4. A Case Study Model for Augmentative and Alternative Communication Outcomes

    Science.gov (United States)

    Hill, Katya

    2006-01-01

    Case studies are an accepted method for reporting treatment outcomes. However, to be useful and authentic, a systematic and principled approach to collecting, analyzing, and reporting case data must be observed. This paper proposes a basic case study format for documenting augmentative and alternative communication (AAC) intervention to ensure…

  5. Antenatal stress: An Irish case study.

    LENUS (Irish Health Repository)

    Carolan-Olah, Mary

    2013-05-16

    BACKGROUND:: stress in pregnancy is common and impacts negatively on women, infants and families. A number of factors contribute to high levels of stress in pregnancy, including financial concerns, marital discord, low support systems and low socio-economic status. OBJECTIVES:: the aim of this study was to evaluate stress anxiety levels and depressive symptoms among low risk women in an area in Ireland that was particularly impacted by the 2008 economic crisis. DESIGN:: a quantitative descriptive cross-sectional design was used. Data were collected using the Edinburgh Postnatal Depression Scale (EPDS), the Perceived Stress Scale and the State Trait Anxiety Inventory (STAI). Data was collected at a single time during the second trimester. SETTING:: this paper reports a case study of one maternity service in Ireland. Participants included low risk pregnant women who were attending the hospital clinic for routine antenatal care. RESULTS:: of 150 questionnaires distributed, 74 completed questionnaires were returned indicating a 49.3% return rate. Findings indicated high levels of stress, anxiety and depressive symptomatology among participants. There were no significant difference in mean EPDS score for different age groups (F4,69=2.48, P=0.052), living arrangements (F4,68=0.90, P=0.5) or usual occupation (F4,69=1.45, P=0.2). A score of ≥12 was taken as indicative of probable antenatal depression and 86.5% of participants responded with a score of 12 or above. PSS scores were also high and more than three quarters of respondents scored ≥15 (75.6%) and more than a third had scores ≥20 (35.1%), out of a total score of 40. There was a significant difference in mean PSS score between the different age groups (F4,69=3.60, P=0.010) but not for living arrangements or usual occupation. A STAI score of ≥39 was taken as indicative of antenatal anxiety, and 74.3% of participants responded with a score of 39 or above. There were no significant differences in mean STAI score between the different age groups (F4,68=1.68, P=0.16), living arrangements (F4,67=2.30, P=0.068) or usual occupations (F4,68=1.25, P=0.3). KEY CONCLUSIONS AND IMPLICATIONS FOR PRACTICE:: this study found high levels of antenatal stress, anxiety, and depressive symptoms in a low risk pregnant population, in an economically impacted region in Ireland. These findings have implications for fetal development and maternal health during pregnancy and in the post partum. Further studies are important to confirm rates and should be conducted over a longer time frame with data collected at more than one point in time, such as mid and late pregnancy. If findings are confirmed, early recognition and treatment of stress, anxiety and depressive symptoms is important to ameliorate some of the harmful effects of these conditions.

  6. Studies on five cases of radiation enterocolitis

    Energy Technology Data Exchange (ETDEWEB)

    Yasunaga, Akira; Shibata, Okihiko; Kubo, Hironobu; Tomonari, Kazuhide; Hadama, Tetsuo; Uchida, Yuzou; Shirabe, Joji (Oita Medical Coll. (Japan))

    1990-05-01

    Five patients with radiation enterocolitis who were surgically treated are reported. The 5 patients had received irradiation therapy more than 5,000 rad for ginecologic malignancies. The period for the onset of symptoms of irradiation enteritis ranged from 8 months to 20 years however, 3 of them developed the symptoms within one year after irradiation therapy. Emergency surgery was carried out for bowel obstruction in 3 cases and for intestinal perforation in 2 cases. Bowel resection and primary anastomosis were performed by a one-step approach in 4 of them. Transient colostomy as preventive measure was added in 2 cases. It is very important for the one-step approach to resect the intestine at the healthy part far from the lesion of irradiation enteritis and to add a transient colostomy to prevent anastomolic insufficiency. Furthermore, suture material should be used less tissue reactive one. (author).

  7. Flexible Structural DBMS Case of Chemical Study

    Directory of Open Access Journals (Sweden)

    A. Chouarfia

    2005-01-01

    Full Text Available DBMS systems and databases in chemistry, whether for retrieval information or retrieval strategy, are usually limited by their procedural reasoning tools. The limitations of usual systems are often caused by a lack of flexibility due to rigid structuration of the search space, the choice of given logic and very often, the fuzzy nature of some of the basic state of space blocks. We are currently investigating the power of analogical search and retrieval tools with an eye to developing a flexible system through the case memory strategy and the use of case memory storing potential similar features chosen by users. The context adaptability parameters, topology, metrics and physical properties.

  8. DDACE cogeneration systems : 10 case studies

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-07-01

    DDACE Power Systems are experts in green energy power generation and provide solutions that deal with waste and industrial by-products. The company develops practical energy solutions that address environmental and financial concerns facing both industrial and municipal customers. The following 10 case studies are examples of the installations that DDACE Power Systems have completed in recent years: (1) a combined heat and emergency power installation on the roof of a 19 storey apartment building on Bloor Street in Toronto, Ontario. The cogeneration package provides electricity and heat to the entire building, replacing an old diesel generator, (2) a combined heat and emergency power installation at the Villa Colombo extended care facility in Vaughan, Ontario. The cogeneration system provides heat and power to the building, as well as emergency power, (3) emergency standby power with demand response capabilities at Sobeys Distribution Warehouse in Vaughan, Ontario. The primary purpose of the 2.4 MW low emission, natural gas fuelled emergency standby generator is to provide emergency power to the building in the event of a grid failure, (4) a dual fuel combined heat and power installation at the Queensway Carleton Hospital in Ottawa, Ontario that provides electricity, hot water and steam to all areas of the hospital, (5) a tri-generation installation at the Ontario Police College in Aylmer, Ontario which provides power and heat to the building as well as emergency power in the event of a grid failure. An absorption chiller provides cooling in the summer and an exhaust emission control system reduces NOx emissions, (6) a biomass gasification installation at Nexterra Energy in Kamloops, British Columbia. The 239 kW generator is fueled by synthesis gas, (7) biogas utilization at Fepro Farms in Cobden, Ontario for treatment of the facility's waste products. The biogas plant uses cow manure, as well as fats, oil and grease from restaurants to produce electricity and heat for the farm, (8) biogas utilization at Highmark Renewables in Vegreville, Alberta. The 1 MW cogeneration system uses cow manure to generate electricity for the power grid. Heat recovered from the engine is used to optimize the anaerobic digester process, (9) a 2.1 MW landfill gas utilization plant at the Halton Region Landfill in Milton, Ontario, and (10) greenhouse cogeneration with CO{sub 2} fertilization at Great Northern Hydroponics in Kingsville, Ontario. The 12 MW cogeneration system provides heat and CO{sub 2} for the greenhouse. Excess electricity is sold to the grid. figs.

  9. Case studies: Soil mapping using multiple methods

    Science.gov (United States)

    Petersen, Hauke; Wunderlich, Tina; Hagrey, Said A. Al; Rabbel, Wolfgang; Stümpel, Harald

    2010-05-01

    Soil is a non-renewable resource with fundamental functions like filtering (e.g. water), storing (e.g. carbon), transforming (e.g. nutrients) and buffering (e.g. contamination). Degradation of soils is meanwhile not only to scientists a well known fact, also decision makers in politics have accepted this as a serious problem for several environmental aspects. National and international authorities have already worked out preservation and restoration strategies for soil degradation, though it is still work of active research how to put these strategies into real practice. But common to all strategies the description of soil state and dynamics is required as a base step. This includes collecting information from soils with methods ranging from direct soil sampling to remote applications. In an intermediate scale mobile geophysical methods are applied with the advantage of fast working progress but disadvantage of site specific calibration and interpretation issues. In the framework of the iSOIL project we present here some case studies for soil mapping performed using multiple geophysical methods. We will present examples of combined field measurements with EMI-, GPR-, magnetic and gammaspectrometric techniques carried out with the mobile multi-sensor-system of Kiel University (GER). Depending on soil type and actual environmental conditions, different methods show a different quality of information. With application of diverse methods we want to figure out, which methods or combination of methods will give the most reliable information concerning soil state and properties. To investigate the influence of varying material we performed mapping campaigns on field sites with sandy, loamy and loessy soils. Classification of measured or derived attributes show not only the lateral variability but also gives hints to a variation in the vertical distribution of soil material. For all soils of course soil water content can be a critical factor concerning a succesful application of geophysical methods, e.g. GPR on wet loessy soils will result in a high attenuation of signals. Furthermore, with this knowledge we support the development of geophysical pedo-transfer-functions, i.e. the link between geophysical to soil parameters, which is active researched in another work package of the iSOIL project. Acknowledgement: iSOIL-Interactions between soil related sciences - Linking geophysics, soil science and digital soil mapping is a Collaborative Project (Grant Agreement number 211386) co-funded by the Research DG of the European Commission within the RTD activities of the FP7 Thematic Priority Environment.

  10. Fragile ?X? syndrome. A case study.

    OpenAIRE

    Mittal S.; Rawal Y

    1996-01-01

    Fragile ?X? syndrome also known as the Martin-Bell syndrome or the marker ?X? syndrome is an ?X?-linked disorder with connective tissue dysplasia and varying degree of mental retardation. A case of this syndrome with characteristic Martin-Bell phenotype is presented. Oral features as yet unmentioned are added.

  11. Olympus Imaging Fraud Scandal: A Case Study

    Science.gov (United States)

    Elam, Dennis; Madrigal, Marion; Jackson, Maura

    2014-01-01

    This case examines the two decade long tobashi scheme by Olympus Imaging Executives to hide $1.7 billion in losses. In the 1980s, a soaring yen and falling dollar caused bottom line income problems for many Japanese companies. Some companies sought to offset the declining revenue with zaiteku, a form of speculative investment. While early…

  12. An investigation of whether factors associated with short-term attrition change or persist over ten years: data from the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS

    Directory of Open Access Journals (Sweden)

    Chatfield Mark

    2006-07-01

    Full Text Available Abstract Background Factors associated with the loss of participants in long-term longitudinal studies of ageing, due to refusal or moves, have been discussed less than those with short term follow-up. Methods In a population-based study of cognition and ageing (the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS, factors associated with dropout due to refusal and moving in the first follow-up period (over two years are compared with factors associated with dropout over ten years. Participants at 10-year follow-up are compared with their age-standardised baseline contemporaries. Results Some consistent trends are found over the longer term. Refusers tended to have poorer cognition, less years of education, not have a family history of dementia and be women. Characteristics of people who moved differed between waves, but the oldest and people in worse health moved more. When surviving and responding individuals at ten years are compared with those of the same age at baseline many differences are found. Individuals of lower social class, education, cognitive ability, in residential care, with sight/hearing problems and poor/fair self-reported health are less likely to be seen after 10 years of follow-up. Individuals report more health problems when they participate in multiple interviews. Conclusion The characteristics of refusers in the longer term are similar to those refusing to participate over the shorter term. Long-term follow-up studies will under represent the disadvantaged and disabled but represent full health status of participating individuals better. There are advantages and disadvantages to both short-term and long-term follow-up.

  13. "Take ten minutes": a dedicated ten minute medication review reduces polypharmacy in the elderly.

    LENUS (Irish Health Repository)

    Walsh, E K

    2012-02-01

    Multiple and inappropriate medications are often the cause for poor health status in the elderly. Medication reviews can improve prescribing. This study aimed to determine if a ten minute medication review by a general practitioner could reduce polypharmacy and inappropriate prescribing in elderly patients. A prospective, randomised study was conducted. Patients over the age of 65 (n = 50) underwent a 10-minute medication review. Inappropriate medications, dosage errors, and discrepancies between prescribed versus actual medication being consumed were recorded. A questionnaire to assess satisfaction was completed following review. The mean number of medications taken by patients was reduced (p < 0.001). A medication was stopped in 35 (70%) patients. Inappropriate medications were detected in 27 (54%) patients and reduced (p < 0.001). Dose errors were detected in 16 (32%). A high level of patient satisfaction was reported. A ten minute medication review reduces polypharmacy, improves prescribing and is associated with high levels of patient satisfaction.

  14. "Take ten minutes": a dedicated ten minute medication review reduces polypharmacy in the elderly.

    LENUS (Irish Health Repository)

    Walsh, E K

    2010-09-01

    Multiple and inappropriate medications are often the cause for poor health status in the elderly. Medication reviews can improve prescribing. This study aimed to determine if a ten minute medication review by a general practitioner could reduce polypharmacy and inappropriate prescribing in elderly patients. A prospective, randomised study was conducted. Patients over the age of 65 (n = 50) underwent a 10-minute medication review. Inappropriate medications, dosage errors, and discrepancies between prescribed versus actual medication being consumed were recorded. A questionnaire to assess satisfaction was completed following review. The mean number of medications taken by patients was reduced (p < 0.001). A medication was stopped in 35 (70%) patients. Inappropriate medications were detected in 27 (54%) patients and reduced (p < 0.001). Dose errors were detected in 16 (32%). A high level of patient satisfaction was reported. A ten minute medication review reduces polypharmacy, improves prescribing and is associated with high levels of patient satisfaction.

  15. Mucocele - A study of 36 cases

    Directory of Open Access Journals (Sweden)

    Jani Dhaval

    2010-01-01

    Full Text Available Background: Mucocele is one of the most common benign soft tissue tumor present in the oral cavity. They are of two types - one is extravasation and second one is retention type but the majority are extravasation type. Aims: The objective is to determine various factors related to mucocele such as role of trauma due to nearby teeth, recurrence, duration, and to find out whether there is any role of psychological stress which initiates trauma like lip or cheek biting. Materials and Methods: 36 cases of mucocele diagnosed at the Department of the Oral Pathology, Govt. Dental College and Hospital, Ahmedabad, between 2004 and 2008 were reviewed. The clinical data were recorded and histopathologic diagnosis was made. Statistical Analysis Used: Data analysis tool, Microsoft Office Excel 2007. Results: A diagnosis of mucocele was established in 36 cases with male-to-female ratio of 1.77:1. Most common type was extravasation in 30 (83.33% cases. The peak age of occurrence was between 1st and 3rd decade. Lateral side of the lower labial mucosa was the most affected site in 34 (94.44% cases. The history of trauma appeared the major etiological factor seen in 28 (77.77% cases. Conclusion: We conclude that there was male predominance and they were more affected in 2nd and 3rd decade. The lateral side of lower labial mucosa was the commonest site and the trauma due to teeth or lip biting was the major etiological factor for the occurrence of the mucocele. The article highlights role of psychological stress in occurrence of mucocele. The reader should understand the importance of histopathology examination and should try to control the psychological stress in such mucocele patients.

  16. Geothermal reservoir assessment case study: Northern Dixie Valley, Nevada

    Energy Technology Data Exchange (ETDEWEB)

    Denton, J.M.; Bell, E.J.; Jodry, R.L.

    1980-11-01

    Two 1500 foot temperature gradient holes and two deep exploratory wells were drilled and tested. Hydrologic-hydrochemical, shallow temperature survey, structural-tectonic, petrologic alteration, and solid-sample geochemistry studies were completed. Eighteen miles of high resolution reflection seismic data were gathered over the area. The study indicates that a geothermal regime with temperatures greater than 400/sup 0/F may exist at a depth of approximately 7500' to 10,000' over an area more than ten miles in length.

  17. The use of case studies in teaching undergraduate neuroscience.

    Science.gov (United States)

    Meil, William M

    2007-01-01

    Case studies have been the cornerstone of many discoveries in neurology and continue to be an indispensable source of knowledge. Attaching a name, face, and story to the study of neurological disorders makes them more "real" and memorable. This article describes the value of the case study methodology and its advantages as a pedagogical approach. It also illustrates how the seminal case of H.M. can be used to highlight the advantages and disadvantages of the case study methodology. Three exercises are described for incorporating case studies into neuroscience courses. The first exercise requires students to conduct a literature review regarding their assigned case and then design an experiment to address a lingering question regarding that neurological disorder. Survey results of 90 students provide quantitative and qualitative support for this approach. The vast majority of students indicated this exercise was a valuable learning experience; sparked interest in the topic and in biopsychology; increased their knowledge and stimulated critical thinking. The second exercise discusses how students might conduct their own case studies. The third exercise emphasizes the use of case studies as a platform to examine competing hypotheses regarding neurological conditions and their treatment. A table listing case studies appropriate for undergraduate neuroscience courses is included. Cases are categorized by the type of neurological disorder and notes regarding the nature of and content of each case are provided. PMID:23493154

  18. T cell rich B cell lymphoma (TCRBCL): study of sixteen cases with review of literature.

    Science.gov (United States)

    Muzaffar, S; Pervez, S; Kayani, N; Soomro, I N; Hasan, S H

    1999-01-01

    T cell rich B cell lymphoma (TCRBCL) is a recently described variant of diffuse non Hodgkin's lymphoma (NHL), the acronym of which has gained wide acceptance among hematopathologists in a relatively shorter period of time. The recognition of this entity requires immunohistochemical facilities especially on paraffin embedded tissues. TCRBCL is one of the many examples in the diagnostic anatomic pathology which emphasizes the need of immunocytochemistry and availability of this technique at least in referral laboratories. One of the differential diagnosis in this case includes lymphocyte predominance Hodgkin's disease (LPHD) which is the most favorable prognostic histologic subtype of Hodgkin's disease (HD) while TCRBCL is an aggressive B Cell NHL and should be treated as high grade large cell lymphoma. The other close differential includes peripheral T cell non-Hodgkin's lymphoma (PTCL). We reported sixteen (16) cases of TcRBCL diagnosed during a period of two and a half years (January 1995 to June 1997). HD and PTCL were the main differential diagnoses in most of these cases. The median age at diagnosis was 39 years and male to female ratio was equal. TCRBCL was nodal in location in 15 cases and a single case in extranodal site presenting as spinal tumor. The mean neoplastic B cell population was 12%, while that of reactive T cells was 82%. A significant polymorphous inflammatory cellular background was noted in 5 cases. Reed-Stenberg like cells were observed in 3 cases. Immunoglobulin light chain restriction studies were performed in fourteen cases and revealed lambda light chains in ten cases while in four cases kappa light chains were present. PMID:10420680

  19. Student and Teacher Perceptions of Industrial Chemistry Case Studies.

    Science.gov (United States)

    Kesner, Miri; Hofstein, Avi; Ben-Zvi, Ruth

    1997-01-01

    Describes a study conducted in Israel that focuses on how studying industrial-chemistry case studies affects students' perceptions of their learning environment and their interest in chemistry studies. Contains 18 references. (DDR)

  20. Osteoid osteoma: A ten-years treatment experience

    Directory of Open Access Journals (Sweden)

    Star?evi? Sr?an

    2004-01-01

    Full Text Available Aim. To review ten-years experience in diagnostics and operative treatment of osteoid osteoma. Methods. A total of 15 patients were retrospectively analyzed in this study. Clinical diagnosis was based on medical check-up, aspirin test, and conventional laboratory and radiographic examinations. CAT scan radionuclide bone scan, and magnetic resonance were performed in certain cases. All the patients were operatively treated by local resection of the tumor-infested bone. The resected part of the bone was intraoperatively checked by X-ray. The aim of this examination was to verify nidus in the resected bone. Afterwards, the resected bone with nidus was histologically analyzed. Results. Osteoid osteoma was histologically verified in 86.6% of cases. Other forms of bone tumors were verified in 13.3%. In the early postoperative period patients were without previous discomforts. Future treatment consisted of regular medical check-up of all the patients. In order to verify the final results, in February 2002 another medical check-up was performed for 11 patients, upon their consent. All of the patients with verified osteoid osteoma were without discomforts. Medical findings were regular in each case. Conventional radiography showed a solid bone remodelling in place of resected bone. Conclusion. Osteoid osteoma is a benign bone tumor with typical clinical and radiographic findings. Operative treatment represents a method of choice and demands accurate preoperative localization of the lesion, with the help of computer-assisted tomography.