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1

Frictional amyloidosis in Oman - A study of ten cases  

Directory of Open Access Journals (Sweden)

Full Text Available Macular amyloidosis is an important cause for cutaneous pigmentation, the aetiology of which is poorly understood. Friction has recently been implicated the causation of early lesions, referred to as frictional amyloidosis. Confirmation of diagnosis by the detect on of amyloid using histochemical stains is inconsistent. Ten patients with pigmentation suggestive of macular amyloidosis were studied with detailed history, clinical examination, biopsy for histochemistry and electron microscopy. Nine out of ten patients had a history of prolonged friction with various objects such as bath sponges, brushes, towels, plant sticks and leaves. Amyloid was demonstrated by histochemical staining in only six out of ten cases. In the remaining four cases, amyloid was detected by electron microscopy. These consisted of aggregates of non-branching, extracellular, intertwining fibres measuring between 200-500 nm in length and between 20-25 nm in diameter. The study confirms the role of friction in the causation of this condition. Histochemical stains are not always successful in the detection of amyloid and electron microscopy is helpful for confirming its presence. The term frictional amyloidosis aptly describes the condition.

Mysore Venkataram; Bhushnurmath Shivayogi; Muirhead David; Al - Suwaid Abdul Raouf

2002-01-01

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Cystic thymomas. A clinicopathologic study of ten cases.  

UK PubMed Central (United Kingdom)

Cystic degeneration in thymoma is a relatively frequent but focal event. In rare cases, the process proceeds to the extent that most or all of the lesion becomes cystic. The authors studied ten cases of thymoma undergoing cystic degeneration of such degree that the lesions initially were mistaken grossly and microscopically for nonneoplastic thymic cysts. The patients' ages ranged from 23 to 81 years, and the sex distribution was equal. The lesions were characterized by the formation of multiple large cystic cavities filled with clear, hemorrhagic or grumose material. Histologically, residual solid islands showing the characteristic features of thymoma, i.e., biphasic cell population (epithelial cells/lymphocytes), perivascular spaces, and areas of medullary differentiation, were present within the cyst walls. In contrast with nonneoplastic thymic cysts, the walls of the cavities generally were devoid of an epithelial lining; most of the cysts appeared to predominantly result from extreme dilatation and confluence of perivascular spaces. In some instances, the cystic degeneration of the tumor was accompanied by cystic changes of an inflammatory nature in the surrounding, nonneoplastic thymic tissue leading to firm adhesions and apparent infiltration of adjacent mediastinal structures. None of the lesions in the studied patients recurred during follow-up periods of from 2 to 10 years (average follow-up, 5 years). Cystic thymomas should be distinguished from nonneoplastic congenital and acquired thymic cysts and other primary thymic neoplasms undergoing extensive cystic degeneration. It is important not to misinterpret the apparent infiltration of surrounding mediastinal structures that results from the inflammatory changes that often accompany these tumors as evidence of aggressive or malignant behavior.

Suster S; Rosai J

1992-01-01

3

Desmoplastic malignant melanoma: a study of ten cases and status of BRAF mutation.  

UK PubMed Central (United Kingdom)

BACKGROUND: Desmoplastic malignant melanoma (DM) is a rare variant of melanoma. BRAF gene mutations have been poorly explored in this entity. OBJECTIVE: To detect BRAF gene mutation in a series of DM. Methods: This is a single-center retrospective study of ten patients with DM, with a biomolecular analysis of BRAF mutation. RESULTS: The male:female ratio was 2.3:1, with a mean patient age of 66.5 years. Melanoma arose in the head and neck region in 3 cases. The mean tumor thickness was 7.97 mm, Clark level was IV or V in all cases. Six melanomas were of the pure DM variant. Three patients had at least one local recurrence, two had regional node metastases, and two experienced systemic metastases which they died of (average follow-up 34.1 months). A V600E BRAF mutation was detected in only one patient. CONCLUSION: BRAF mutation seems to be a rare event in DM contrary to other melanoma variants.

Coupelon S; Franck F; Jarrousse AS; Déchelotte P; Souteyrand P; D'Incan M

2012-01-01

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Making a difference: Ten case studies of DSM/IRP interactive efforts and related advocacy group activities  

Energy Technology Data Exchange (ETDEWEB)

This report discusses the activities of organizations that seek to promote integrated resource planning and aggressive, cost-effective demand-side management by utilities. The activities of such groups -- here called energy efficiency advocacy groups (EEAGs) -- are examined in ten detailed am studies. Nine of the cases involve some form of interactive effort between investor-owned electric utilities and non-utility to develop policies, plans, or programs cooperatively. Many but not all of the interactive efforts examined are formal collaboratives. In addition, all ten cases include discussion of other EEAG activities, such as coalition-building, research, participation in statewide energy planning, and intervention in regulatory proceedings.

English, M.; Schexnayder, S.; Altman, J. [Tennessee Univ., Knoxville, TN (United States). Energy, Environment and Resources Center; Schweitzer, M. [Oak Ridge National Lab., TN (United States)

1994-03-01

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PURPA Resource Development in the Pacific Northwest : Case Studies of Ten Electricity Generating Powerplants.  

Energy Technology Data Exchange (ETDEWEB)

The case studies in this document describe the Public Utilities, Regulatory Policies Act (PURPA) development process for a variety of generating technologies. Developer interactions with regulatory agencies and power purchasers are described in some detail. Equipment, installation, and maintenance costs are identified; power marketing considerations are taken into account; and potential environmental impacts, with corresponding mitigation approaches and practices are summarized. The project development case studies were prepared by the energy agencies of the four Northwest states, under contract to the Bonneville Power Administration.

Washington State Energy Office.

1990-07-01

6

Medulloblastoma—Treatment and Prognosis A Study of Seventeen Cases in Ten Years  

Digital Repository Infrastructure Vision for European Research (DRIVER)

In a series of 17 biopsy-proved cases of medulloblastoma all patients were treated by megavoltage irradiation in the Stanford University Division of Radiation Therapy. The entire craniospinal axis was treated in each case. The five-year survival in the series was 27 percent.

Probert, John C.; Bagshaw, Malcolm A.; Lederman, Marcos

7

Clinical features of ten cases of osteopoikilosis.  

UK PubMed Central (United Kingdom)

A retrospective study was carried out of the ten cases of osteopoikilosis seen at this Orthopedic Unit over a 15-year period in order to determine the reasons why patients seek consultation, preliminary diagnosis, and associated lesions. Eight patients consulted for problems not related to the locomotor apparatus, and diagnosis was by chance; the other two presented joint pain. The preliminary diagnosis was osteoblastic metastasis in five patients and osteopoikilosis in the other five. None of the patients displayed skin or visceral involvement, but three presented bone alterations. Definitive diagnosis was made by measurement of biochemical markers of bone remodeling, radiography of both hands, and bone scan. Bone biopsy was performed in one case. Although rare, the radiographic symptoms of osteopoikilosis are sufficiently specific to avoid false diagnoses, which may give rise to rigorous and expensive studies for other important disorders.

Carpintero P; Abad JA; Serrano P; Serrano JA; Rodríguez P; Castro L

2004-12-01

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A ten year study of STD Cases in an urban clinic in Calcutta  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Total 16440 patients attended the STD clinic during the 10 years period of study from 1984 to 1993. From 1988 number of STD caes were gradually decreasing probably due to less promiscuity in fear of AIDS and different measures taken to prevent transmission of HIV infection. But it does not lessen th...

Ghosh Sadhana; Roy Alok

9

A ten year study of STD Cases in an urban clinic in Calcutta  

Directory of Open Access Journals (Sweden)

Full Text Available Total 16440 patients attended the STD clinic during the 10 years period of study from 1984 to 1993. From 1988 number of STD caes were gradually decreasing probably due to less promiscuity in fear of AIDS and different measures taken to prevent transmission of HIV infection. But it does not lessen the importance of STD control, because syphilis is still prevalent (8%) with congenital syphilis. Peak in the incidence of chancroid (15%) is alarming as this may lead to increased transmission of HIV infection in near future. Male unmarried constituted the bulk of STD sufferers (44%) and married males (34%), while female unmarried and married patients were 1% and 20% respectively, 5.7% of antenatal mothers were strongly seroreactive for syphilis. Therefore all antenatal mothers should be screened for STD and routine serological test for syphilis should be done.

Ghosh Sadhana; Roy Alok

1994-01-01

10

Lifeline electric rates and alternative approaches to the problems of low-income ratepayers: ten case studies of rejected programs  

Energy Technology Data Exchange (ETDEWEB)

This volume, Volume 3, contains ten case studies of non-implemented programs. It is noted that in Volume 2, the implemented lifeline programs, evolved as policy closely after the 1973 oil embargo; in contrast, the rejected programs were initiated about 4 years later and considered in a more-complex policy environment - after which time alternate methods of assisting low-income people had been developed. Specifically presented here are program summary, issue development, governmental process, and impact for the following: (a) Delaware Senate Bill 202; (b) Illinois House Bill 83; (c) Maine Legislative Document No. 1043; (d) Minnesota House File 1243; (e) New York Assembly Bill 12214; (f) New York Senate Bill 7013-A; (g) Rhode Island Resolution 79-H 5770-A; (h) South Dakota Senate Joint Resolution 9; (i) West Virginia House Bill 943; and (j) Wisconsin Assembly Bill 1250. 4 figures, 24 tables.

1980-07-01

11

The Application of the Ten Group Classification System (TGCS) in Caesarean Delivery Case Mix Adjustment. A Multicenter Prospective Study  

Science.gov (United States)

Background Caesarean delivery (CD) rates are commonly used as an indicator of quality in obstetric care and risk adjustment evaluation is recommended to assess inter-institutional variations. The aim of this study was to evaluate whether the Ten Group classification system (TGCS) can be used in case-mix adjustment. Methods Standardized data on 15,255 deliveries from 11 different regional centers were prospectively collected. Crude Risk Ratios of CDs were calculated for each center. Two multiple logistic regression models were herein considered by using: Model 1- maternal (age, Body Mass Index), obstetric variables (gestational age, fetal presentation, single or multiple, previous scar, parity, neonatal birth weight) and presence of risk factors; Model 2- TGCS either with or without maternal characteristics and presence of risk factors. Receiver Operating Characteristic (ROC) curves of the multivariate logistic regression analyses were used to assess the diagnostic accuracy of each model. The null hypothesis that Areas under ROC Curve (AUC) were not different from each other was verified with a Chi Square test and post hoc pairwise comparisons by using a Bonferroni correction. Results Crude evaluation of CD rates showed all centers had significantly higher Risk Ratios than the referent. Both multiple logistic regression models reduced these variations. However the two methods ranked institutions differently: model 1 and model 2 (adjusted for TGCS) identified respectively nine and eight centers with significantly higher CD rates than the referent with slightly different AUCs (0.8758 and 0.8929 respectively). In the adjusted model for TGCS and maternal characteristics/presence of risk factors, three centers had CD rates similar to the referent with the best AUC (0.9024). Conclusions The TGCS might be considered as a reliable variable to adjust CD rates. The addition of maternal characteristics and risk factors to TGCS substantially increase the predictive discrimination of the risk adjusted model.

Maso, Gianpaolo; Alberico, Salvatore; Monasta, Lorenzo; Ronfani, Luca; Montico, Marcella; Businelli, Caterina; Soini, Valentina; Piccoli, Monica; Gigli, Carmine; Domini, Daniele; Fiscella, Claudio; Casarsa, Sara; Zompicchiatti, Carlo; De Agostinis, Michela; D'Atri, Attilio; Mugittu, Raffaela; La Valle, Santo; Di Leonardo, Cristina; Adamo, Valter; Smiroldo, Silvia; Frate, Giovanni Del; Olivuzzi, Monica; Giove, Silvio; Parente, Maria; Bassini, Daniele; Melazzini, Simona; Guaschino, Secondo; De Seta, Francesco; Demarini, Sergio; Travan, Laura; Marchesoni, Diego; Rossi, Alberto; Simon, Giorgio; Zicari, Sandro; Tamburlini, Giorgio

2013-01-01

12

The application of the Ten Group classification system (TGCS) in caesarean delivery case mix adjustment. A multicenter prospective study.  

UK PubMed Central (United Kingdom)

BACKGROUND: Caesarean delivery (CD) rates are commonly used as an indicator of quality in obstetric care and risk adjustment evaluation is recommended to assess inter-institutional variations. The aim of this study was to evaluate whether the Ten Group classification system (TGCS) can be used in case-mix adjustment. METHODS: Standardized data on 15,255 deliveries from 11 different regional centers were prospectively collected. Crude Risk Ratios of CDs were calculated for each center. Two multiple logistic regression models were herein considered by using: Model 1- maternal (age, Body Mass Index), obstetric variables (gestational age, fetal presentation, single or multiple, previous scar, parity, neonatal birth weight) and presence of risk factors; Model 2- TGCS either with or without maternal characteristics and presence of risk factors. Receiver Operating Characteristic (ROC) curves of the multivariate logistic regression analyses were used to assess the diagnostic accuracy of each model. The null hypothesis that Areas under ROC Curve (AUC) were not different from each other was verified with a Chi Square test and post hoc pairwise comparisons by using a Bonferroni correction. RESULTS: Crude evaluation of CD rates showed all centers had significantly higher Risk Ratios than the referent. Both multiple logistic regression models reduced these variations. However the two methods ranked institutions differently: model 1 and model 2 (adjusted for TGCS) identified respectively nine and eight centers with significantly higher CD rates than the referent with slightly different AUCs (0.8758 and 0.8929 respectively). In the adjusted model for TGCS and maternal characteristics/presence of risk factors, three centers had CD rates similar to the referent with the best AUC (0.9024). CONCLUSIONS: The TGCS might be considered as a reliable variable to adjust CD rates. The addition of maternal characteristics and risk factors to TGCS substantially increase the predictive discrimination of the risk adjusted model.

Maso G; Alberico S; Monasta L; Ronfani L; Montico M; Businelli C; Soini V; Piccoli M; Gigli C; Domini D; Fiscella C; Casarsa S; Zompicchiatti C; De Agostinis M; D'Atri A; Mugittu R; La Valle S; Di Leonardo C; Adamo V; Smiroldo S; Frate GD; Olivuzzi M; Giove S; Parente M; Bassini D; Melazzini S; Guaschino S; De Seta F; Demarini S; Travan L; Marchesoni D; Rossi A; Simon G; Zicari S; Tamburlini G

2013-01-01

13

[Ocular syphilis: ten new cases and review of the literature].  

UK PubMed Central (United Kingdom)

INTRODUCTION: Ocular manifestations in patients with syphilis may involve almost any of the structures of the eye. OBJECTIVES: To describe ten new cases of syphilis with eye involvement and to briefly discuss the management and therapy of such condition. MATERIAL AND METHODS: Ten cases were retrospectively studied over 13 years. Demographic factors, ophthalmologic examination, and laboratory tests were assessed. RESULTS: Seven of the 10 cases were male and 3 were female. The mean age of patients was 39,7 years. Disease presentation included: panuveitis (6 patients), optic neuritis (3), retinal vasculitis (1) and Argyll-Robertson pupil (1). Cerebrospinal fluid VDRL test was positive in 6 patients and 3 patients were HIV (+). CONCLUSIONS: Syphilis is able to display diverse ophthalmologic manifestations. Not in all the cases the CSF-VDRL test was positive. Antitreponemal therapy generates a fast and effective response in the affected patients.

Romero C P; Urzúa S C; Gallardo V P; Verdaguer T J; Lechuga C M; Hernández N H; Sanhueza Z F; Andaur L M; Donaire V E

2010-12-01

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[Rendu-Osler-Weber disease. Contribution of ten cases  

UK PubMed Central (United Kingdom)

Ten new cases of hereditary hemorrhagic telangiectasia (Rendu-Osler-Weber's disease) are presented. Five of them were detected among 30,000 patients attending a Service of Internal Medicine; the remainder five, were detected while conducting the family study. Epistaxis (5 cases) and hidden (2 cases) and evident (1 case) digestive hemorrhage were the most frequent clinical signs. All patients presented telangiectasia affecting lips. We observed edemas in nasal fossas (5 cases), hand fingers (6 cases), tongue (2 cases) and face (1 case), as well as in gastroduodenal mucosa in the three patients undergoing endoscopic study. We did not observed hemostasis disorders, except for moderate thrombocytosis in two patients and microcytic anemia in three patients. The relevance of clinical evaluation is stressed, because all patients presented oral-facial telangiectasia.

Rodríguez Cuartero A; González Martínez F; Rodríguez Cuartero F; Ceballos Torres A

1992-03-01

15

Lifeline electric rates and alternative approaches to the problems of low-income ratepayers. Ten case studies of implemented programs  

Energy Technology Data Exchange (ETDEWEB)

Program summaries, issue developments, governmental processes, and impacts are discussed for 10 case studies dealing with lifeline electric rates and alternative approaches to the problems of low-income ratepayers, namely; the Boston Edison rate freeze; the California lifeline; Florida Power and Light conservation rate; the Iowa-Illinois Gas and Electric small-use rate; the Maine demonstration lifeline program; the Massachusetts Electric Company A-65 rate; the Michigan optional senior citizen rate; the Narragansett Electric Company A-65 SSI rate; the Northern States Power Company conservation rate break; and the Potomac Electric Power Company rate freeze. (MCW)

1980-07-01

16

Subtotal Hemispherectomy, Report of Ten Cases  

Directory of Open Access Journals (Sweden)

Full Text Available 10 cases submitted to subtotal hemispheretomy are discussed. In selected group of infantile hemiplegia where epilepsy and behaviour disturbances are pr~sent, and investigations prove that the other hemisphere is farly normal, thts operation is of greatt benefit. Ne,vertheless long follow-up of these cases IS necessary before a final judgement can be passed. Age should.be no barrier to selection, as those of 18 - 25 have benefited as much as young children

N. O. Ameli

1960-01-01

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Subtotal Hemispherectomy, Report of Ten Cases  

Digital Repository Infrastructure Vision for European Research (DRIVER)

10 cases submitted to subtotal hemispheretomy are discussed. In selected group of infantile hemiplegia where epilepsy and behaviour disturbances are pr~sent, and investigations prove that the other hemisphere is farly normal, thts operation is of greatt benefit. Ne,vertheless long follow-up of these...

N. O. Ameli

18

[Rheumatoid arthritis in the elderly: ten cases report].  

UK PubMed Central (United Kingdom)

BACKGROUND: The occurrence of rheumatoid arthritis (RA) in elderly is frequent. If the reality of a real difference in clinical presentation between younger and older subjects is discussed, the central point remains that the prognosis is not better for the elderly. Finally, conventional treatment is as effective and safe as in younger patients, and the same stringent targets for management of the PR used for young subjects must be applied in the elderly. AIM: To identify the characteristics of RA in the elderly in its epidemiological, clinical, radiological, evolutive and therapeutic. METHODS: We conducted a retrospective study of RA in the elderly aged 65 and over, we've compiled ten cases hospitalized over a period of 4 1/2 years in the service of Internal Medicine, Habib Thameur Hospital (Tunis). Results: There were 8 women and 2 men. The average age was 70.6 years. The onset of arthritis and the disease was progressive in seven cases. An inflammatory syndrome was present in seven cases. Rheumatoid factor was positive in eight cases. Five patients were classified as stage III and IV according to the radiological classification of Steinbrocker. The treatment was based on painkillers and anti-inflammatory drugs in all cases. Long-term treatment was initiated in seven patients. The outcome was favorable in all cases. CONCLUSION: Late-onset RA is a heterogeneous framework in which multiple clinical forms deserve to be individualized and should reflect this diversity, rather than approach to the problem of global RA after 60 years.

Ben Dhaou B; Boussema F; Aydi Z; Baili L; Kochbati S; Rokbani L

2012-06-01

19

[Structural abnormalities of the Y chromosome. Observations in ten cases  

UK PubMed Central (United Kingdom)

The authors report ten cases of structural anomalies involving the Y chromosome: five cases of a dicentric Y chromosome, one ring Y chromosome, one case of a Y isochromosome containing the long arms, one deletion of the long arms (Yq-), one case of an abnormally long Y chromosome (Yq+) and one Y-autosome translocation. Analysis of clinical and chromosomal correlations, especially with respect to sexual differentiation, led to discussing the role of the Y chromosome.

Mattei JF; Mattei MG; Lucas C; Giraud F

1979-03-01

20

[Transcervical myomectomy and uterine fibroids: report of ten cases].  

UK PubMed Central (United Kingdom)

BACKGROUND: Uterine fibroids are the most common tumors of the uterus, their distribution in anatomical layers and segments of it are very varied clinical manifestations are usually abnormal bleeding and known treatments, the surgery is the most accomplished, either myomectomy or hysterectomy by both endoscopy and laparotomy, transvaginal approach is less common, but consider it a right way and solving the problem in selected cases. OBJECTIVE: To present a well-defined study protocol in patients with abnormal uterine bleeding, and myomectomy as a surgical transcervical simple, safe and effective in patients with intracavitary myoma protruded through the cervical canal. MATERIAL AND METHODS: ten patients are presented with abnormal uterine bleeding and anemia of various degrees, studied over a period of two years, following a research protocol for clinical methods, cabinet and laboratory diagnosis was submucosal fibroids with single fibroid, pedunculated protruding a vagina, treatment was performed transcervical myomectomy. RESULTS: The surgical procedure was obtained by solving the problem, having found the ten patients in the subsequent revisions in the outpatient, asymptomatic and without tumor lesions in the uterus. CONCLUSIONS: This study shows that performing a notarization in patients with abnormal uterine bleeding and making appropriate surgical treatment, achieves the desired objectives.

Cano López H; Cano Aguilar HE; Cano Aguilar FD

2012-10-01

 
 
 
 
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THE ROLE OF PUBLIC RELATIONS IN A NON-GOVERNMENTAL ORGANIZATION: A CASE STUDY OF TEN SELECTED CHRISTIAN CHURCHES IN MAIDUGURI  

Directory of Open Access Journals (Sweden)

Full Text Available The study set out to examine the role of public Relations in a non-governmental organization, using ten selected Christian Churches as a case study. The objectives of the study are to examine the nature and practice of Public Relations in NGOs with particular reference toChristian Churches, how Public Relations can be used in propagating the image of Christian Churches in Maiduguri, to identify likely problems Churches encountered in the use of Public Relations and recommend ways of improving Public Relations practice within and outside the selected Christian Churches in Maiduguri. The study found out that 50% of the respondents said they do not have functional Public Relations unit in their Churches. 40% of those who responded said they used video coverage of programmes to publicize the Church activities, while another 88.89% of the respondents said they used public Relations to propagate the gospel. The study found out that finance, lack of PR expertise, the size of the Church andignorance were the major problems associated with Public Relations practice in churches. Solution proffered for these problems include: allocation of enough fund, training leaders, creating awareness and reorganization of administrative structure. Among other things thestudy recommended that each department in a Christian Church should have Public Relations unit apart from the Public Relations unit of the Church. By so doing each arm of the church will attract members of the external public to become members of the church. The studyconcluded that to avoid Christian Church activities from being shrouded in secrecy, Christian Churches no matter their size should have Public Relations units to publicize the Church activities using the most widely acceptable medium.

James Mathew; Peter M. Ogedebe

2012-01-01

22

Angioleiomyoma: magnetic resonance imaging features in ten cases  

International Nuclear Information System (INIS)

Angioleiomyoma is a rare, benign smooth muscle tumour arising from the tunica media of small veins and arteries and can occur anywhere in the body. The histological appearances are well documented, but there are relatively few descriptions of the magnetic resonance imaging (MRI) findings. A retrospective study of the clinical presentation, MRI appearances and histological findings of ten angioleiomyomas presenting as extremity soft tissue masses. MRI typically demonstrated a well-defined, oval mass located superficial to the fascia with the commonest sites being the hand (three cases) and ankle/foot (five cases). The lesion was isointense to muscle on T1-weighted spin echo images with heterogeneous increased internal T2W/short tau inversion recovery (STIR) signal intensity, which commonly appeared as multiple linear or branching areas of hyperintensity. Enhancement after IV gadolinium ranged from diffuse to heterogeneous. In a single case, central fat signal intensity was seen, while a further case showed marked T2W/STIR hypointensity due to diffuse hyalinisation within the lesion. This is the largest reported MRI series of extremity musculoskeletal angioleiomyoma. Angioleiomyoma should be considered in the differential diagnosis of a superficial mass in the hand or foot, particularly when characteristic linear or branching hyperintensity is seen on T2W or STIR images. (orig.)

2008-01-01

23

Angioleiomyoma: magnetic resonance imaging features in ten cases  

Energy Technology Data Exchange (ETDEWEB)

Angioleiomyoma is a rare, benign smooth muscle tumour arising from the tunica media of small veins and arteries and can occur anywhere in the body. The histological appearances are well documented, but there are relatively few descriptions of the magnetic resonance imaging (MRI) findings. A retrospective study of the clinical presentation, MRI appearances and histological findings of ten angioleiomyomas presenting as extremity soft tissue masses. MRI typically demonstrated a well-defined, oval mass located superficial to the fascia with the commonest sites being the hand (three cases) and ankle/foot (five cases). The lesion was isointense to muscle on T1-weighted spin echo images with heterogeneous increased internal T2W/short tau inversion recovery (STIR) signal intensity, which commonly appeared as multiple linear or branching areas of hyperintensity. Enhancement after IV gadolinium ranged from diffuse to heterogeneous. In a single case, central fat signal intensity was seen, while a further case showed marked T2W/STIR hypointensity due to diffuse hyalinisation within the lesion. This is the largest reported MRI series of extremity musculoskeletal angioleiomyoma. Angioleiomyoma should be considered in the differential diagnosis of a superficial mass in the hand or foot, particularly when characteristic linear or branching hyperintensity is seen on T2W or STIR images. (orig.)

Gupte, Cynthia; Butt, Sajid H.; Saifuddin, Asif [Royal National Orthopaedic Hospital, Department of Radiology, Middlesex (United Kingdom); Tirabosco, Roberto [Royal National Orthopaedic Hospital, Department of Histopathology, Middlesex (United Kingdom)

2008-11-15

24

A temporal-spatial postprocessing model for probabilistic run-off forecast. With a case study from Ulla-Førre with five catchments and ten lead times  

Science.gov (United States)

This work is driven by the needs of next generation short term optimization methodology for hydro power production. Stochastic optimization are about to be introduced; i.e. optimizing when available resources (water) and utility (prices) are uncertain. In this paper we focus on the available resources, i.e. water, where uncertainty mainly comes from uncertainty in future runoff. When optimizing a water system all catchments and several lead times have to be considered simultaneously. Depending on the system of hydropower reservoirs, it might be a set of headwater catchments, a system of upstream /downstream reservoirs where water used from one catchment /dam arrives in a lower catchment maybe days later, or a combination of both. The aim of this paper is therefore to construct a simultaneous probabilistic forecast for several catchments and lead times, i.e. to provide a predictive distribution for the forecasts. Stochastic optimization methods need samples/ensembles of run-off forecasts as input. Hence, it should also be possible to sample from our probabilistic forecast. A post-processing approach is taken, and an error model based on Box- Cox transformation, power transform and a temporal-spatial copula model is used. It accounts for both between catchment and between lead time dependencies. In operational use it is strait forward to sample run-off ensembles from this models that inherits the catchment and lead time dependencies. The methodology is tested and demonstrated in the Ulla-Førre river system, and simultaneous probabilistic forecasts for five catchments and ten lead times are constructed. The methodology has enough flexibility to model operationally important features in this case study such as hetroscadasety, lead-time varying temporal dependency and lead-time varying inter-catchment dependency. Our model is evaluated using CRPS for marginal predictive distributions and energy score for joint predictive distribution. It is tested against deterministic run-off forecast, climatology forecast and a persistent forecast, and is found to be the better probabilistic forecast for lead time grater then two. From an operational point of view the results are interesting as the between catchment dependency gets stronger with longer lead-times.

Engeland, K.; Steinsland, I.

2012-04-01

25

TENS in refractory angina pectoris. Three case reports.  

UK PubMed Central (United Kingdom)

OBJECTIVE: To demonstrate the use of transcutaneous electrical nerve stimulation (TENS) in the treatment of refractory angina pectoris. CLINICAL FEATURES: Three cases are presented. Patient 1 was a 56-year-old man with a 20-year history of angina pectoris. Angiography revealed extensive stenoses of coronary arteries. He was deemed unsuitable for coronary bypass surgery due to significant distal coronary disease. Patient 2 was an 81-year-old woman with angina that responded poorly to increasing drug therapy: she also had extensive stenoses but was judged unsuitable for surgery. Patient 3 was a 69-year-old man who had previously undergone two coronary bypass procedures and presented with unstable rest angina. The patient was deemed unsuitable for a third coronary artery bypass operation due to distal disease and the small calibre of the intermediate artery. INTERVENTION AND OUTCOME: Each patient had TENS added to their treatment regimen (one hour twice a day for Patient 1; one hour three times a day for Patients 2 and 3). Patient 1 experienced a marked reduction in pain which lasted for over a year before symptoms of angina again worsened. Patient 2 has experienced no further pain of angina except on occasions when her TENS unit was not working or she neglected to use it as prescribed. Patient 3 had been free of angina from commencement of TENS therapy on review three months later. CONCLUSION: TENS may be useful in the treatment of angina pectoris which is refractory to medical therapy when the patient is not suitable for revascularisation procedures or revascularisation has failed. The mechanism of action is probably a combination of analgesia per se and inhibition of sympathetic nervous stimulation of the heart.

West PD; Colquhoun DM

1993-04-01

26

Maternal Mortality: Ten Years Retrospective Study  

Directory of Open Access Journals (Sweden)

Full Text Available To study the maternal mortality and common complication leading to maternal death over a period of10yrs from Jan 1999 to Dec. 2009.A retrospective study of hospital records and death summaries of allmaternal deaths over 10 yr periods was carried out. MMR of 270.33/1,00,000 live births was observedover a period of 10 yrs. post partum hemorrhage was the leading direct cause and anemia the leadingindirect cause. Most women died within 24 hrs of admission. The age group of 20-30 yrs was crucial.Most deaths were in unbooked cases transferred from outside. Hemorrhage and PIH are major causesof death. Most maternal deaths are one preventable by quality health education of women & adequatecare to the mothers at all levels district health system

Nishu Priya, Verma Ashok, Verma Suresh

2010-01-01

27

Firework injuries: a ten-year study.  

UK PubMed Central (United Kingdom)

Fireworks are used worldwide to celebrate popular events (e.g. festivals, official celebrations, weddings). The festival of lights (Diwali) is celebrated with fireworks in India. During this period, many patients from all age groups present to hospital with injuries due to fireworks. Prevalence, period of occurrence, sex and age variation, adult supervision, causative fireworks, mode of lighting, age groups prone to injury, patterns of injury caused by individual fireworks, and the body parts injured were studied. One hundred and fifty-seven cases (92 retrospective, 65 prospective) with injury due to fireworks presenting to the Department of Plastic Surgery at KEM Hospital between 1997 and 2006 were studied. The prevalence of injuries has decreased steadily over the last 10 years (41 cases in 1997, 3 cases in 2006). The maximum number of injuries (35%) was seen in the age group 5-14 years; 92% of these children were unsupervised. The commonest cause of injury was firework misuse (41% of cases), followed by device failure (35%). Device failure was commonest with flares/fountains (ground firework emitting sparks upwards) and aerial devices. Flare/fountains caused most injury (39%), sparklers the least (0.6%). Flare/fountains, ground spinners, sparklers, and gunpowder (explosive material from cracker, obtained by tearing paper wrapper and obtaining chemicals) caused only soft tissue burns; stringbombs (high-intensity fire cracker made by wrapping chemicals with jute strings/coir in layers) and rockets (aerial device that zooms upwards and bursts) caused blast injuries, leading to soft tissue disruption and bony injuries. Emergency surgery was done if indicated: tendon and/or neurovascular repair, fracture fixation, flap cover or amputation. Superficial burns were treated with dressings. Certain wounds needed only thorough cleansing of the wound and primary suturing. We concluded that, over a 10-year period, the prevalence of firework injury decreased due to increased awareness in the community. Aggressive awareness campaigns by government and non-government organisations was the cause. We can minimise the number and severity of accidents by raising awareness regarding safety precautions, encouraging professional displays and motivating manufacturers to adhere to strict quality control.

Puri V; Mahendru S; Rana R; Deshpande M

2009-09-01

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Cancer profile in Kolar: A ten years study  

Directory of Open Access Journals (Sweden)

Full Text Available Context: Cancer profile varies in different regions and depends on race, lifestyle and diet. The study of a cancer profile helps to know the common cancers in a particular population, its probable risk factors and also helps in cancer control programs. AIM: To study the cancer profile at Kolar, based on Pathology Department records. Settings and Design: Retrospective study from January 1997 to December 2006. Materials and Methods: Cancer cases diagnosed by fine needle aspiration cytology (FNAC) and histopathology in the Department of Pathology were included in the study. The relevant history, clinical findings, and sociodemographic information of each case was retrieved from hospital records. Statistical Analysis Used: Descriptive statistics. Results: Out of a total of 19,615 cases reported at the Department of Pathology, 2,744 (13.98%) were cancer cases. The peak incidence was in the fifth decade in females and the seventh decade in males. Male : Female ratio was 0.7 : 1. Overall there was a steady rise in the number of cases from year 1997 to 2006. The top ten cancers in males were of oral cavity, stomach, esophagus, bone, non-Hodgkin?s lymphoma (NHL), prostate, liver, larynx, penis, and Hodgkin?s disease / bladder and those in females were oral cavity, cervix, breast, stomach, esophagus, thyroid, ovary, bone, rectum, and melanoma. Conclusions: Oral cavity and upper gastrointestinal cancers predominated in both genders. In females, cervical cancer predominated over breast cancer. Thyroid cancers were relatively more common in this region especially in females.

Kalyani R; Das S; Bindra Singh M; Kumar HML

2010-01-01

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[Brain abscess in childhren: A ten cases report  

UK PubMed Central (United Kingdom)

OBJECTIVES: Considering that the brain abscess is rare in infants, with a high mortality rate, the objective of this paper is to report the clinical evolution of ten children with the diagnosis of brain abscess in the Pediatric Nursery of the Hospital das Clínicas of the Medical School of the Campinas State University (UNICAMP).METHODS: The data of the patients with diagnosis of brain abscess recorded between January 1986 and July 1995 were reviewed. The following data were analyzed: age, sex, clinical manifestations, physical examination, radiological data, etiological agent, treatment, complications and clinical evolution of the patients.RESULTS: The age of the patients varied from 2 to 13 years (median 3 years); 6 of them were female. The neurological manifestations predominated, and 2 patients had history of prior otorhinolaryngological infection (chronic otitis media and sinusitis). Two patients had congenital cyanogenic cardiopathy (Fallot tetralogy and Pulmonary Stenosis with Interventricular Communication). The diagnosis and follow-up were made with computed tomography of the brain. In six cases there were one sole abscess located more frequently in the frontal lobe. The treatment in majority of the cases was broad-spectrum antibiotic association and surgical drainage. Five patients had neurological sequelae (seizure, hydrocephalus and paresis); one death occurred.CONCLUSIONS: Although rare, the brain abscess has to be remembered in patients that have neurological alterations associated to risk factors, as otorhinolaryngological infections and congenital cyanotic cardiopathy, being mandatory the realization of computed tomography of the brain to confirm the diagnosis.

Pereira RM; Scotoni AE; Belangero VM; Bucaretchi F; Tresoldi AT

1998-01-01

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Simulation Study of TenTen: A new Multi-TeV IACT array  

CERN Document Server

TenTen is a proposed array of Imaging Atmospheric Cherenkov Telescopes (IACT) optimized for the gamma ray energy regime of 10 TeV to 100 TeV, but with a threshold of ~1 to a few TeV. It will offer a collecting area of 10 km2 above energies of 10 TeV. In the initial phase, a cell of 3 to 5 modest-sized telescopes, each with 10-30 m2 mirror area, is suggested for an Australian site. A possible expansion of the array could comprise many such cells. Here we present work on configuration and technical issues from our simulation studies of the array. Working topics include array layout, telescope size and optics, camera field of view, telescope trigger system, electronics, and site surveys.

Stamatescu, V; Clay, R; Dawson, B; Denman, J; Dunbar, R; Protheroe, R; Smith, A; Thornton, G; Wild, N

2007-01-01

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Ten cases of sebaceous carcinoma arising in nevus sebaceus.  

Science.gov (United States)

Although nevus sebaceus is known to develop various types of secondary neoplasms, it rarely causes carcinoma and only 14 cases of secondary sebaceous carcinoma have been reported. In this study, 10 cases of sebaceous carcinoma arising in nevus sebaceus were collected. The clinicopathological features and results of immunohistochemical examinations with adipophilin, perilipin and p53 were summarized. Sebaceous carcinoma arising in nevus sebaceous predominantly occurred on the scalp (8/10) of elderly women (mean age, 67.7 years). No case was associated with Muir-Torre syndrome. We found several pathological features of sebaceous carcinoma; that is, made up mainly of germinative cells, moderate nuclear atypia without pleomorphism and many mitoses (4-28/10 high-power field). Adipophilin and perilipin antibodies highlighted lipid drops in the cytoplasm of the malignant cells in all cases. Overexpression of p53 was seen in all cases. In two cases there were coexisting benign-looking sebaceous lesions at the periphery of the main cancer nodule, and in these lesions p53 showed low positivity compared with the clearly malignant area. There was co-occurrence of another neoplasm in three cases with trichoblastoma, sebaceoma and syringocystadenoma papilliferum, respectively. All cases were treated by excision of the malignant lesion, with or without inclusion of the nevus sebaceus. In a follow-up period of 1-7 years, there was no case of recurrence, lymph node metastases or distant metastases. With these specific pathological and immunohistochemical findings using adipophilin, perilipin and p53, we have to consider the possibility that there is a tendency to underdiagnose secondary sebaceous carcinomas in nevus sebaceus. These clinicopathological features of sebaceous carcinomas developing in the nevus sebaceus seem to indicate different biological entities from de novo sebaceous carcinoma. PMID:19120764

Izumi, Miki; Tang, Xiaoyan; Chiu, Cheng-Sheng; Nagai, Takeshi; Matsubayashi, Jun; Iwaya, Keiichi; Umemura, Shinobu; Tsuboi, Ryoji; Mukai, Kiyoshi

2008-11-01

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Optical Intraday Variability Studies of Ten Low Energy Peaked Blazars  

CERN Document Server

We have carried out optical (R band) intraday variability (IDV) monitoring of a sample of ten bright low energy peaked blazars (LBLs). Forty photometric observations, of an average of ~ 4 hours each, were made between 2008 September and 2009 June using two telescopes in India. Measurements with good signal to noise ratios were typically obtained within 1-3 minutes, allowing the detection of weak, fast variations using N-star differential photometry. We employed both structure function and discrete correlation function analysis methods to estimate any dominant timescales of variability and found that in most of the cases any such timescales were longer than the duration of the observation. The calculated duty cycle of IDV in LBLs during our observing run is ~ 52%, which is low compared to many earlier studies; however, the relatively short periods for which each source was observed can probably explain this difference. We briefly discuss possible emission mechanisms for the observed variability.

Rani, Bindu; Joshi, U C; Ganesh, S; Wiita, Paul J

2011-01-01

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Primary lymphoma of the central nervous system: a clinical-pathological and immunohistochemical study of ten autopsy cases Linfoma primário do sistema nervoso central: estudo clínico-patológico e imuno-histoquímico de dez casos de necropsia  

Directory of Open Access Journals (Sweden)

Full Text Available CONTEXT: Primary central nervous system lymphomas (PCNSL) are a rare subgroup of lymphomas generally associated with HIV and EBV. OBJECTIVE: To study ten autopsy cases of PCNSL, to describe the neuropathological findings, to characterize the phenotype of the neoplastic cells, to detect EBV in the lesion and to compare the findings with the clinical and laboratory data of the patients. METHOD: The clinical, histological and immunohistochemical data of ten cases of PCNSL, eight cases from patients with AIDS, identified among 265 autopsies of these patients were analyzed. RESULTS: Seven patients were males and the mean age was 40.9 years. The most frequent symptomatology was focal neurologic deficit (70%). Six patients presented with only one lesion. Histologically, densely cellular and polymorphous neoplasms with angiocentrism were observed, in 90% of cases. An association with other diseases was observed in four cases. Most patients had diffuse large B cell non-Hodgkin’s lymphoma. EBV was detected by immunohistochemistry in only one case. The lack of detection of the virus might have been due to the long time of fixation of the brain which might have inactivate epitopes therefore compromising the testing. CONCLUSION: In the present series, PCNSL presented with focal symptoms, with unifocal or multifocal lesions, with a predominant B-cell CD20 positive phenotype, rarely associated with EBV.CONTEXTO: Linfoma primário do sistema nervoso central (LP-SNC) é raro subgrupo de linfomas relacionado à AIDS, geralmente associado EBV. OBJETIVO: Identificar os achados clínico-patológicos dos pacientes com LP-SNC. MÉTODO: Foram analisados dados clínicos, histológicos e imuno-histoquímicos de dez necrópsias de LP-SNC, oito deles de pacientes com AIDS, identificados entre 265 autopsias destes. RESULTADOS: Sete pacientes foram masculinos e a idade média foi 40,9 anos. A sintomatologia neurológica mais freqüente era focal (70%). Seis exibiram lesão única. Histologicamente, eram neoplasias densamente celulares e polimorfas, com angiocentrismo em 90% dos casos. Em quatro casos, houve associação com outras afecções. A maioria dos casos foi de linfoma não-Hodgkin difuso de grandes células B. A pesquisa para EBV foi positiva em um caso. CONCLUSÃO: Predominaram os LP-SNC associados à AIDS, com sintomatologia focal, lesão em massa ou multifocal, com predominância de células B CD-20.

Henrique Costa; Marcello Franco; Myriam Dumas Hahn

2006-01-01

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Laparoscopic adrenalectomy for primary aldosteronism: report of initial ten cases.  

UK PubMed Central (United Kingdom)

BACKGROUND: Although laparoscopic technique has become popular in the surgical field, the value of laparoscopy in the removal of adrenal gland is unknown. The objective of this study was to examine the feasibility of laparoscopic adrenalectomy. METHODS: Between January 17, 1992, and March 16, 1993, 10 patients (four men, six women; mean, 48.2 years of age) with primary aldosteronism underwent laparoscopic adrenalectomy (seven of left adrenal gland and three of right adrenal gland) with almost the same devices as laparoscopic cholecystectomy. RESULTS: Adrenal tumors were successfully removed with adjacent normal adrenal gland in every patient. The operative time ranged from 165 to 572 minutes (mean, 295 minutes), and the operative bleeding ranged from 50 to 920 ml (mean, 270.5 ml) without requiring blood transfusion. Only one patient required open hemostasis because of uncontrollable bleeding complicated by dislocation of vascular clip in spite of successful laparoscopic removal of adrenal tumor. There was no major complication except for this case. CONCLUSIONS: Laparoscopic adrenalectomy is a relatively safe, alternative operative method for primary aldosteronism, but application of this technique to other types of adrenal lesions remains to be studied.

Takeda M; Go H; Imai T; Nishiyama T; Morishita H

1994-05-01

35

Astrophysical parameters of ten poorly studied open star clusters  

International Nuclear Information System (INIS)

We present the fundamental parameters of ten open star clusters, nominated from Kronberger et al. who presented some newly discovered stellar groups on the basis of the Two Micron All Sky Survey photometry and Digitized Sky Survey visual images. Star counts and photometric parameters (radius, membership, distance, color excess, age, luminosity function, mass function, total mass, and dynamical relaxation time) have been determined for these ten clusters for the first time. In order to calibrate our procedures, the main parameters (distance, age, and color excess) have been re-estimated for another five clusters, which are also studied by Kronberger et al. (research papers)

2012-01-01

36

Progressive hemifacial atrophy: ten-year observation of a case.  

UK PubMed Central (United Kingdom)

The authors describe the case of a 14-year-old girl who experienced progressive hemifacial atrophy at the age of three-and-a-half years. The patient's early age at appearance of the condition resulted not only in atrophy of skin, subcutaneous tissue, and muscles, but also in very severe deformation of the right side of the face due to disorders in growth of cartilaginous and osseous tissue. Changes in her brain case and craniofacial skeleton included enophthalmos, underdevelopment of the eyelids, nose, hard plate, and dental process of the jaw including the premolar teeth, and a lack of the second molar. These changes caused an irregular line of bite. The differential diagnosis excluded hemifacial microsomy and sclerodermal hemifacial atrophy.

Urban J; Toruniowa B; Chibowska M

1996-08-01

37

Treatment of peripheral extremity pain with TENS: A report of three cases  

Digital Repository Infrastructure Vision for European Research (DRIVER)

This paper reviews three cases in which radiculopathies of the cervical and lumbar spine were successfully managed by the use of transcutaneous electrical nerve stimulation (TENS) in addition to, or instead of, spinal manipulative therapy. Characteristics of TENS, indications for its use, and applic...

Thiel, Haymo W; Cassidy, J David; Mierau, Dale R

38

Stevens Johnson syndrome, toxic epidermal necrolysis and SJS-TEN overlap: A retrospective study of causative drugs and clinical outcome  

Directory of Open Access Journals (Sweden)

Full Text Available Background and Aims: Stevens Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) and SJS-TEN overlap are serious adverse cutaneous drug reactions. Drugs are often implicated in these reactions. Methods: A retrospective analysis of inpatients? data with these dermatological diagnoses were carried out for three years, to study the causative drugs, clinical outcome, and mortality in these conditions. Results: Thirty patients (15 TEN, nine SJS-TEN overlap, and six SJS) were admitted. In 21 cases, multiple drugs were implicated whereas single drugs were responsible in nine. Anticonvulsants (35.08%) were the most commonly implicated drugs followed by antibiotics (33.33%) and NSAIDS (24.56%). Twenty-five patients recovered whereas five died (four TEN, one SJS-TEN overlap). Conclusion: Anticonvulsants, antibiotics and NSAIDs were the most frequently implicated drugs. TEN causes higher mortality than both SJS and SJS-TEN overlap.

Sharma Vinod; Sethuraman Gomathy; Minz Anil

2008-01-01

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Hemicrania continua: a report of ten new cases  

Directory of Open Access Journals (Sweden)

Full Text Available Hemicrania continua (HC) is an uncommon primary headache first described as a syndrome in 1984. Being quite unusual, its clinical characterization still demands better description. The aim of this study is to present the main clinical characteristics of 10 patients with the diagnosis of HC seen in a tertiary center, critically discussing their main features. All subjects had strictly unilateral headache without side shift and absolute response to indomethacin. Seven patients (70%) presented autonomic features during pain exacerbations. Four (40%) had migrainous symptoms during the exacerbations and one presented partial relief with dihydroergotamine. One patient had pain excruciatingly severe during the exacerbations. Although the cardinal features of HC - continuous, unilateral, indomethacin responsive, remain strongly reliable, a refinement on the clinical characterization is needful and desired.

Bigal Marcelo E.; Tepper Stewart J; Sheftell Fred D.; Rapoport Alan M.

2002-01-01

40

Tuberculose meningo-encefalica na infância: estudo anatomo-patologico de 10 casos Tuberculosis of the central nervous system in the childhood: anatomo-pathological study of ten cases  

Directory of Open Access Journals (Sweden)

Full Text Available Estudo anátomo-patológico de 10 casos de tuberculose do SNC em crianças, com idade inferior a 10 anos. São enfatizadas as alterações macro e microscópicas produzidas pela tuberculose nas meninges, parênquima nervoso e vasos. Os achados clínicos e patológicos são discutidos e correlacionados com a literatura. Os autores concluem que: 1) a lesão, em crianças com tuberculose do SNC, é geralmente uma meningoencefalite proliferativa; 2) o parênquima nervoso pode ser afetado por propagação contígua do processo tuberculoso ou por alterações circulatórias secundárias a lesões arteriais; 3) por causa da localização dos vasos endocranianos no espaço sub-aracnóideo, eles são geralmente lesados pelo processo inflamatório, que determina uma endarterite obliterante, a qual pode ser observada por angiografia carotídea.The anatomo-pathological study of ten cases of tuberculosis of the central nervous system (CNS) in children under 10 years old is reported. The emphasis is given to the macroscopic and microscopic changes produced by the tuberculosis in the meninges, in the nervous parenchyma and in the vessels. The clinical and pathological findings are discussed and correlated with the literature. The authors concluded that: 1) the lesion in children with tuberculosis of the CNS is generally a proliferative meningoencephalitis; 2) the nervous parenchyma may be affected by the contiguous propagation of the tuberculous process or by the circulatory changes secondary to the arterial lesions; 3) because of the localization of the endocranial vessels in the sub-arachnoidal space they are generally injured by the inflammatory process, which can determine an obliterating endarteritis, which can be observed by a carotid angiography.

Ligia M. Barbosa Coutinho; Ricardo Petinelli Tarragô

1976-01-01

 
 
 
 
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Calcific myonecrosis: A report of ten new cases with an emphasis on MR imaging  

International Nuclear Information System (INIS)

The aim of this study is to report the typical radiographic and MR imaging features of calcific myonecrosis, which help to distinguish this rare entity from other causes of a calcifying calf mass. Ten patients with a final diagnosis of calcific myonecrosis were referred to a specialist orthopaedic oncology service in a 5-year period with the presumptive diagnosis of malignancy based on recent clinical presentation and imaging findings. Radiographs were available for retrospective review in all ten cases and MR imaging in six. All patients presented with a slow-growing painless calf mass. All gave a history of major trauma to the lower leg many years before, but in only two cases did the referring clinician query whether trauma might be a contributory factor. Radiographs showed well-defined fusiform mineralised masses up to 25 cm in length arising within the calf. The calcification was consistently peripheral and plaque-like. Ossification was not present. MR imaging showed the anterior compartment to be involved in four cases and all compartments in two. T1- and T2-weighted images showed peripheral low signal intensity, more prominent on the T2-weighted images, because of the peripheral mineralization. The contents of the masses were variable on T1-weighted images depending on the differing amounts of blood breakdown products and were heterogeneous on T2-weighted images. The latter may be explained by a combination of the mineralisation and T2 shortening due to blood breakdown products. A gadolinium chelate, administered in two cases, failed to show any appreciable enhancement. Calcific myonecrosis has characteristic clinical, radiographic and MR features that should make the condition easy to recognise. Despite its rarity, it should be included in the differential diagnosis of focal mineralisation of the calf. (orig.)

2004-01-01

42

Calcific myonecrosis: A report of ten new cases with an emphasis on MR imaging  

Energy Technology Data Exchange (ETDEWEB)

The aim of this study is to report the typical radiographic and MR imaging features of calcific myonecrosis, which help to distinguish this rare entity from other causes of a calcifying calf mass. Ten patients with a final diagnosis of calcific myonecrosis were referred to a specialist orthopaedic oncology service in a 5-year period with the presumptive diagnosis of malignancy based on recent clinical presentation and imaging findings. Radiographs were available for retrospective review in all ten cases and MR imaging in six. All patients presented with a slow-growing painless calf mass. All gave a history of major trauma to the lower leg many years before, but in only two cases did the referring clinician query whether trauma might be a contributory factor. Radiographs showed well-defined fusiform mineralised masses up to 25 cm in length arising within the calf. The calcification was consistently peripheral and plaque-like. Ossification was not present. MR imaging showed the anterior compartment to be involved in four cases and all compartments in two. T1- and T2-weighted images showed peripheral low signal intensity, more prominent on the T2-weighted images, because of the peripheral mineralization. The contents of the masses were variable on T1-weighted images depending on the differing amounts of blood breakdown products and were heterogeneous on T2-weighted images. The latter may be explained by a combination of the mineralisation and T2 shortening due to blood breakdown products. A gadolinium chelate, administered in two cases, failed to show any appreciable enhancement. Calcific myonecrosis has characteristic clinical, radiographic and MR features that should make the condition easy to recognise. Despite its rarity, it should be included in the differential diagnosis of focal mineralisation of the calf. (orig.)

Dhillon, M.; Davies, A.M.; Benham, J.; Evans, N. [Royal Orthopaedic Hospital, Department of Radiology, Birmingham (United Kingdom); Mangham, D.C. [Royal Orthopaedic Hospital, Department of Pathology, Birmingham (United Kingdom); Grimer, R.J. [Royal Orthopaedic Hospital, Department of Orthopaedic Oncology, Birmingham (United Kingdom)

2004-11-01

43

Monoamine oxidase inhibitors: ten years of docking studies.  

UK PubMed Central (United Kingdom)

The number of papers dealing with the structure-based drug design is continuously growing, which demonstrates the importance of such tools in medicinal chemistry. In the current paper, the published literature concerning the use of the ligand-protein docking methodologies in the study of the monoamine oxidase (MAO) enzymes was reviewed. Ten years of studies aimed at developing new compounds active as MAO inhibitors (MAOIs) were covered. The literature regarding thiazole, caffeine, pyrazole, chromone, indeno-pyridazin, ?-carboline, indole, coumarin, anilide and amphetamine derivatives, was discussed in some detail. It is apparent that, through this computational approach, more selective and potent molecules can be proposed as inhibitors by applying precise modifications on the basic scaffold.

Ferino G; Vilar S; Matos MJ; Uriarte E; Cadoni E

2012-01-01

44

Online Customer Relationships - An Empirical Study of Ten Swedish . . .  

UK PubMed Central (United Kingdom)

In the past few years, the business environment has changed with the evolution ofelectronic commerce. Enticed by the Internet and its opportunities, companies arestarting to offer online retailing. With fast pace of growth at hand, there is a riskthat online retailers will be overly fond of exploiting the Internet and consequently,might fail to satisfy the customers needs With high competition and low switchingcosts between marketplaces and retailers, it is important to consider how to buildonline customer relationships that can generate customer retention. In this paper,we examine if and how online retailers act to build online customer relationships.We do this with the purpose of exploring online customer relationships. Anempirical study of ten Swedish online retailers has been conducted. The researchdata have been collected in tree different ways; by interacting with the companiesthrough e-mail, by purchasing goods and by gathering and analysing informationfrom their web...

Annakarin Nyberg; Henrik Lindh

45

Hepatopulmonary hydatidosis in a ten-year-old girl: a case report  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Introduction Hydatid disease is a parasitic infection caused by the tapeworm Echinococcus granulosus and is characterised by cystic lesions in the liver and lungs. Concomitant pulmonary and hepatic localization of hydatid cysts in childhood is unusual and represents a distinct clinical entity called hepatopulmonary hydatidosis. Case presentation A ten-year-old Caucasian girl, a permanent resident of rural Greece, was admitted to hospital reporting a nonspecific symptomatology compatible with a diagnosis of viral infection. Chest radiography revealed a large homogenous circular opacity in the right lung field. On the basis of imaging studies, a diagnosis of hydatidosis was made with synchronous hepatic and pulmonary involvement, successfully managed through a single-stage transthoracic surgical approach. Conclusion This case report highlights the necessity of realizing that hydatid disease continues to be a public health problem, which often remains asymptomatic for years. Therefore, the presence of any homogeneous cystic spherical opacity on routine chest radiography should raise the suspicion of hydatid disease, mainly in endemic areas such as Greece. General practitioners and physicians involved in pediatric care need to be familiar with the diagnosis and management of the variable clinical manifestations of hydatid disease. Taking into consideration that hepatopulmonary hydatidosis represents a special entity that requires a different therapeutic approach may positively affect its economic and social-related burden.

Anyfantakis Dimitrios; Blevrakis Evangellos; Vlachakis Ioannis; Arbiros Ioannis

2010-01-01

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Anti-NMDA receptor encephalitis: report of ten cases and comparison with viral encephalitis.  

UK PubMed Central (United Kingdom)

The California Encephalitis Project (CEP), established in 1998 to explore encephalitic etiologies, has identified patients with N-methyl-D-aspartate receptor (NMDAR) antibodies, the likely etiology of their encephalitis. This study compares the presentation of such patients to those with viral encephalitis, so that infectious disease clinicians may identify individuals with this treatable disorder. Patients were physician-referred, and standardized forms were used to gather demographic, clinical, and laboratory data. Features of anti-NMDAR+ patients were compared with the viral encephalitides of enteroviral (EV), rabies, and herpes simplex-1 (HSV-1) origins. Sixteen cases with confirmed viral etiologies were all negative on NMDAR antibody testing. Ten anti-NMDAR+ patients were profiled with a median age of 18.5 years (range 11-31 years). None were Caucasian. They had a characteristic progression with prominent psychiatric symptoms, autonomic instability, significant neurologic abnormalities, and seizures. Two had a teratoma, and, of the remaining eight, four had serologic evidence of acute Mycoplasma infection. The clinical and imaging features of anti-NMDAR+ patients served to differentiate this autoimmune disorder from HSV-1, EV, and rabies. Unlike classic paraneoplastic encephalitis, anti-NMDAR encephalitis affects younger patients and is often treatable. The association of NMDAR antibodies in patients with possible Mycoplasma pneumoniae infection warrants further study.

Gable MS; Gavali S; Radner A; Tilley DH; Lee B; Dyner L; Collins A; Dengel A; Dalmau J; Glaser CA

2009-12-01

47

Primary renal carcinoid natural history of the disease for ten years: case report  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background Primary renal carcinoid is extremely rare and there are few reports on the natural history of the disease. Case presentation A 68-year-old male with a right renal mass who lost to follow-up for ten years has been presented. His only complaint was a mild flank pain. Upon admission to the hospital for his renal mass, he underwent a right radical nephrectomy and pathological examination revealed the diagnosis of primary renal carcinoid. Conclusions In light of the presented case, primary renal carcinoma may have a prolonged natural history with no distant metastasis and any change in the quality of life of the patient.

Gunes Ali; Yilmaz Ugur; Ugras Murat; Mizrak Bulent

2002-01-01

48

Case Studies  

International Nuclear Information System (INIS)

Proven options available to Sri Lanka for large scale electricity generation in the future are coal-fired thermal, oil-fired thermal and Nuclear. Four case studies for groups participated are indicated. Case study for group 1 is comparison of the three options by taking into consideration the capital and recurrent expenditure involved. Environmental effects of the three options are also given. Case study for group 2 is economic comparison of three renewable energy based power generation system. Case study for group 3 is based on energy conservation, efficiency, improvement and demand management. Assuming that a continuous saving of 20 MW of demand from 1996 onwards is effective two projects are suggested to achieve this result. Case study for group 4 is a feasibility study for hydro power development of the Kukule Ganga (river) in Sri Lanka. Participants are required to evaluate one of the three optional development concepts which are technically feasible

1994-01-01

49

A study of ten quasars with redshifts greater than four  

Energy Technology Data Exchange (ETDEWEB)

Four quasars with redshifts greater than four were detected in a low-resolution CCD grism survey. CCD photometry and high S/N, moderate resolution spectra are presented for these quasars and the six other known quasars with redshifts above 4. The M sub B values of nine of the objects are between -27.5 and -25, with the tenth quasar having an M sub B value of -29. The emission lines and shapes of the continua of these ten quasars are similar to those of lower-redshift quasars. The results suggest that the C IV emission lines in high-redshift quasars may be weaker than those in lower-redshift quasars. The continua of all of the high-redshift quasars display strong depressions blueward of the Ly-alpha emission line. 31 refs.

Schneider, D.P.; Schmidt, M.; Gunn, J. E. (Institute for Advanced Study, Princeton, NJ (USA) Palomar Observatory, Pasadena, CA (USA) Princeton Univ. Observatory, NJ (USA))

1989-11-01

50

Cancer profile in Kolar: A ten years study  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Context: Cancer profile varies in different regions and depends on race, lifestyle and diet. The study of a cancer profile helps to know the common cancers in a particular population, its probable risk factors and also helps in cancer control programs. AIM: To study the cancer profi...

Kalyani R; Das S; Bindra Singh M; Kumar HML

51

A case of a solitary form of Castleman disease: ten-year follow-up.  

UK PubMed Central (United Kingdom)

Castleman disease (CD) is a rare atypical lymphoproliferative process of obscure pathogenesis. An intracranial localization of the condition is extremely rare. We present a case of a 29-year-old man, who harbored an intracranial plasma cell variant of CD in the form of a tumor mimicking meningioma and was followed up to 10 years after surgical excision of the lesion. The histopathological examination showed massive infiltration of mononuclear cells, composed mainly of lymphocytes and matured plasmocytes, as well as many small thin-walled vessels surrounded with plasma cells and lymphocytes. This picture was consistent with a plasma cell type of CD. Ten-year follow-up supports a notion that total surgical excision of the solitary intracranial infiltration is curative in plasma cell type of CD.

Turek G; Resze? J; Kochanowicz J; Hermanowicz A; Mariak Z

2013-03-01

52

The Gestational Trophoblastic Diseases: A Ten Year Retrospective Study  

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Full Text Available Background: Gestational trophoblastic disease (GTD) defines a heterogenenous group ofinterrelated lesions that arise from the trophoblastic epithelium of the placenta. There are severalhistologically distinct types of GTD: hydatiform mole (complete or partial), persistant/invasivegestational trophoblastic neoplasia (GTN), choriocarcinoma and placenta site trophoblastictumors. The aim of this study was to determine the frequency and risk factors of GTD amongwomen admitted to Imam Khomeini Hospital in Ahvaz, Iran.Materials and Methods: This was a cross-sectional study conducted at Imam KhomeiniHospital in Ahvaz, Iran. All hospital records related to GTD (132) from 1996 until 2006 werereviewed. Demographic and histo-pathologic characteristics were extracted. Chi-square andFisher-exact tests were used to analyze all variables. P ? 0.05 was considered statisticallysignificant. SPSS, version 11 was used for statistical analysis.Results: The mean age of patients was 27.6 years. Most patients who presented with GTDwere of ages 18-35 years (71.3%). There was no relationship between age and hydatiformmole during the reproductive years. There were 28 (18.9%) patients over the age 40, of which18 (15.90%) of these had a complete hydatiform mole. Within this group, 9 (6.8%) changedto a persistent mole. There was a significant relationship between age over 40 and completemole (p<0.02). The percentage of patients with blood groups A and O was the same (37.9%).There was a significant relationship between blood groups (O+ and A+) and complete mole(p<0.05).Conclusion: The most common age range for hydatiform mole was 18-35 years. Women overthe age of 40 had a more complete hydatiform mole, which is similar to the other countries.Age and blood group are two risk factors for hydatiform mole.

Razieh Mohammadjafari; Parvin Abedi; Mitra Tadayon Najafabady

2010-01-01

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Bateman bipolar hip arthroplasty for femoral neck fractures. A five- to ten-year follow-up study.  

UK PubMed Central (United Kingdom)

Displaced femoral neck fractures in 128 patients were treated with cemented Bateman universal proximal femoral bipolar hemiarthroplasties. The follow-up period ranged from five to ten years. In the surviving 49 cases, the average follow-up period was seven years and five months. Seventy-nine percent of surviving patients had no or slight pain after their primary procedure. None of these patients developed acetabular protrusio. Ten percent of the survivors required late revision; 88% of the unrevised hips had no or slight pain. When compared with studies of noncemented Moore and Thompson fixed-head prostheses, the cemented Bateman bipolar prosthesis had decreased protrusio and less pain.

LaBelle LW; Colwill JC; Swanson AB

1990-02-01

54

Bacteriological profile of community acquired acute bacterial meningitis: A ten-year retrospective study in a tertiary neurocare centre in South India  

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Purpose: Ten years retrospective study to evaluate the bacteriological spectrum of community acquired acute bacterial meningitis (CAABM). Methods: Cerebrospinal fluid (CSF) samples from 385 clinically suspected cases of pyogenic meningitis were processed for cell counts, cytospin Gr...

Mani R; Pradhan S; Nagarathna S; Wasiulla R; Chandramuki A

55

Radiology and pathology of malignant fibrous histiocytomas of the soft tissues; a report of ten cases  

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Malignant fibrous histiocytomas (MFH) are believed to originate from histiocytes and are composed of malignant cells with spindle or round shapes. We evaluated ten MFH of the soft tissues by plain roentgenograms, computed tomography (CT), and angiography and subdivided them into four grades of anaplasia and five predominant histologic variants. The variants of MFH demonstrated different vascular patterns. The extension of the lesions could be determinded by CT and angiography. CT is the method of choice in the assessment of size and extent of MFH of the soft tissues. When intra-arterial chemotherapy is indicated the angiograms obtained at each catheter placement may substitute CT in follow-up studies obviating additional diagnostic procedures.

Fischer, H.J.; Lois, J.F.; Gomes, A.S.; Mirra, J.M.; Deutsch, L.S.

1985-03-01

56

Radiology and pathology of malignant fibrous histiocytomas of the soft tissues a report of ten cases  

International Nuclear Information System (INIS)

Malignant fibrous histiocytomas (MFH) are believed to originate from histiocytes and are composed of malignant cells with spindle or round shapes. We evaluated ten MFH of the soft tissues by plain roentgenograms, computed tomography (CT), and angiography and subdivided them into four grades of anaplasia and five predominant histologic variants. The variants of MFH demonstrated different vascular patterns. The extension of the lesions could be determinded by CT and angiography. CT is the method of choice in the assessment of size and extent of MFH of the soft tissues. When intra-arterial chemotherapy is indicated the angiograms obtained at each catheter placement may substitute CT in follow-up studies obviating additional diagnostic procedures. (orig.)

1985-01-01

57

Spectrum of gastro-intestinal cancers--a ten-year study.  

UK PubMed Central (United Kingdom)

Pattern of gastro-intestinal malignancies differ in different geographical areas and depends upon the genetic, cultural, dietary and socioeconomic factors. Therefore studying pattern of gastro-intestinal cancers help to identify high risk groups, recommend preventive measures or advise appropriate screening in high risk population. The present study was undertaken to determine the pattern of gastrointestinal malignancies at Kolar, situated in south-eastern part of Karnataka. A ten-year retrospective study from January 1997 to December 2006 was done at the department of pathology at Sri Devaraj Urs Medical College, Kolar, Karnataka. All the gastro-intestinal malignancies diagnosed were retrieved from pathology department records and socio-epidemiological data regarding each case was collected from hospital record section. The cases were analysed for site of involvement, age distribution, histological types and yearwise distribution by descriptive analysis. Gastro-intestinal malignancies constituted 22.96% of all the malignancies diagnosed. Males were more frequently affected than females, M:F ratio was 1:0.6. Peak incidence was in 7th decade. Stomach was the commonest site (48.4%) followed by oesophagus (27.7%), rectum (6.5%), colon (5.0%) and primary liver cancer (4.76%). Majority of histological type was adenocarcinoma. Yearwise distribution showed gradual increase in incidence of cancer. In the present study gastro-oesophageal malignancies was the most common gastro-intestinal malignancy in this part of Karnataka which in turn reflects on potential lifestyle and environmental factors.

Kalyani R; Das S; Kumar ML

2010-10-01

58

Prognostic factors in children with acute lymphoblastic leukemia: a ten year study  

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Full Text Available Background: Acute lymphoblastic leukemia (ALL) is the most common cancer in the pediatric population. With modern treatments, the chance of the complete recovery is nearly 100%. The most important prognostic factors are appropriate treatment protocol and determination of patient risk factors based on clinical, morphological, immunological and cytological characteristics. In this study we reviewed frequency of these factors, like as age, gender, the primary white blood cell number, sub- group on the base of FAB classification, immunophenotype and the clinical progress. Methods: In this retrospective study, we reviewed 877 pediatric patients with the diagnosis of ALL between the years of 1994 and 2004. In these patients the age, gender, primary WBC count, sub-group based on the FAB classification, immunophenotype and the clinical progress in 177 patient with acute lymphoblastic leukemia at Imam Khomeini Hospital between the years of 1994 to 2004 were determined. Results: Of these patients, 1.6% was younger than one year, 24.8% more than ten years old and 73.6% were between the ages of one and ten years; 63.8% were male. WBC counts were above 50,000/ul in 28.8% of the patients. FAB classifications included L1 in 80.2%, L2 in 17.5% and L3 in 2.3% of the patients. Immunophenotypes included pre-B cell in 63.8%, early pre-B cell in 23.1%, T cell in 12.3% and mature B cell in 0.8% of the patients. Marker CD10+ was detected in 88.1% of the B cell cases. In this study group, 74% of the patients recovered, 16.3% died and 16.5% relapsed.Conclusions: The prevalence of FAB-L1 and pre-B cell cases in this study is greater than a previous study, while the prevalence of FAB-L2 and early pre-B cell cases is less than that of the previous study.

Oloomi yazdi Z.

2008-01-01

59

Casing study  

Energy Technology Data Exchange (ETDEWEB)

An unorthodox method of casing drilling used by Tesco Corporation at a gas well in Wyoming to drill deeper using casings as drillpipe is discussed. The process involves either rotating the casing as drill string or using a downhole mud motor to rotate the bit. In this instance, the surface hole and the production hole were casing-drilled to a record 8,312 feet by rotating the casing. The 8 1/2-inch surface hole was drilled with 7-inch casing to 1,200 feet using a Tesco underreamer and a polycrystalline pilot bit; drilling and cementing was completed in 12 1/2 hours. The 6 1/4-inch production hole was drilled with 4 1/2-inch casing and the bottomhole assembly was retrieved after 191 hours rotating. This case was the first in which the entire well was casing-drilled from surface to TD. Penetration rate compared favorably with conventional methods: 12 1/2 hours for casing-drilling to 18.9 hours for conventional drilling, despite the fact that the casing-drilling technology is still in its infancy. It is suggested that casing-drilling has the potential to eliminate the need for the drillpipe entirely. If these expectations were to be realised, casing-drilling could be one of the most radical drilling changes in the history of the oil and gas industry. 1 photo.

Roche, P.

2000-12-01

60

Autologous and Acrylic Cranioplasty: A Review of Ten Years and 258 Cases.  

UK PubMed Central (United Kingdom)

INTRODUCTION: Cranioplasty is a well-accepted neurosurgical procedure that has application to a wide range of pathologies. Given the varied need for both autologous and synthetic cranial grafts, it is important to establish rates of procedural complication. METHODS: A retrospective review identified 282 patients undergoing cranioplasty at our institution over a ten-year period, of which 249 patients underwent 258 cranioplasties with either autologous or acrylic flaps. A database including patient age, gender, presenting diagnosis, hospital of surgery, presence of a drain and surgical complications was created in order to analyze the autologous and acrylic cranioplasty data. RESULTS: A total of 28 complications were noted, yielding a rate of 10.9% (28/258). There was no statistically significant difference in infection rate between autologous and acrylic cranioplasty (7.2% v. 5.8%, p=0.80). Male patients (p=0.007), tumor patients (p=0.02) and patients undergoing surgery at the county hospital (p=0.06) sustained a statistically higher rate of infection. Amongst traumatic brain injury (TBI) patients, complex injuries and surgical involvement of the frontal sinus carried a significantly higher infection rate of 17% and 38.5%, respectively (p=0.03, p=0.001). Post-operative epidural hematoma requiring re-operation occurred in 3.5% (9/258) with no difference in hematoma rate with placement of a drain (p=1). CONCLUSIONS: Cranioplasty carries a significant risk of infection and post-operative hematoma. In this large series comparing autologous and acrylic flaps, male patients, tumor patients and those undergoing surgery at the county hospital were at increased risk of post-operative infection. Amongst TBI cases, complex injuries and cases with surgical involvement of the frontal sinus may portend a higher risk.

Klinger DR; Madden C; Beshay J; White J; Gambrell K; Rickert K

2013-09-01

 
 
 
 
61

High Intensity Laser Therapy (HILT) versus TENS and NSAIDs in low back pain: clinical study  

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Low back pain, caused by lumbar disc herniation, is prevalently treated with a conservative approach. In this study we valued the efficacy of High Intensity Laser Therapy (HILT), compared with accepted therapies such as TENS and NSAIDs. Laser therapy obtained similar results in the short term, but better clinical effect over time than TENS and NSAIDs. In conclusion high intensity laser therapy appears to be a interesting new treatment, worthy of further research.

Zati, Allesandro; Fortuna, Damiano; Valent, A.; Filippi, M. V.; Bilotta, Teresa W.

2004-09-01

62

[Treatment of Poland syndrome thorax deformity with the lipomodeling technique: about ten cases].  

UK PubMed Central (United Kingdom)

The correct management, with the classic techniques, of the thoracic deformity in Poland's syndrome is difficult, with often insatisfactory results. The current surgical treatment involves the use of prothetic material and/or different flaps with their own complications and scares. The experience of our team with fat grafting (we named lipomodeling) in breast reconstruction helped us to propose the correction of the thoracic and mammary deformity by repeated fat transfer sessions. Fat grafting is commonly used in our team since 1998 in various indication of breast surgery. We reviewed retrospectively our ten first cases of thoracic deformity in Poland's syndrome treated with only fat grafting. Patients had repeated procedures until obtaining a satisfactory result. The fat was harvested from the thigh, buttocks, and abdomen. There were young patients with a mean age of 16years old (from 12 to 24). The mean follow-up was 51months. An average of 2.9 procedures (1 to 5) with 255cm(3) of fat injection at each procedure was needed to obtain symetry. Hundred percent of the patients were satisfied. No complication was noted. As reported, the reconstruction of the thoracic deformity and the mammary shape can be obtained by fat grafting. The absence of a flap donor site sequelae and the absence an implant allow this technique to be simple, reproductible, and without great complication. These criteria match well the surgical management of this deformity, which is mainly aesthetic. Moreover, the secondary benefit of liposuction of disgracious steatomery helps the acceptance of the procedure. Therefore in our hands, fat grafting to the breast (lipomodeling) is now our first choice treatment in thoracic Poland syndrome deformity. Given the rarity of this syndrome, we recommend a treatment by an operator who makes the learning curve of lipomodeling, and who often deals with Poland syndrome.

La Marca S; Delay E; Toussoun G; Ho Quoc C; Sinna R

2013-02-01

63

[Treatment of Poland syndrome thorax deformity with the lipomodeling technique: about ten cases].  

Science.gov (United States)

The correct management, with the classic techniques, of the thoracic deformity in Poland's syndrome is difficult, with often insatisfactory results. The current surgical treatment involves the use of prothetic material and/or different flaps with their own complications and scares. The experience of our team with fat grafting (we named lipomodeling) in breast reconstruction helped us to propose the correction of the thoracic and mammary deformity by repeated fat transfer sessions. Fat grafting is commonly used in our team since 1998 in various indication of breast surgery. We reviewed retrospectively our ten first cases of thoracic deformity in Poland's syndrome treated with only fat grafting. Patients had repeated procedures until obtaining a satisfactory result. The fat was harvested from the thigh, buttocks, and abdomen. There were young patients with a mean age of 16years old (from 12 to 24). The mean follow-up was 51months. An average of 2.9 procedures (1 to 5) with 255cm(3) of fat injection at each procedure was needed to obtain symetry. Hundred percent of the patients were satisfied. No complication was noted. As reported, the reconstruction of the thoracic deformity and the mammary shape can be obtained by fat grafting. The absence of a flap donor site sequelae and the absence an implant allow this technique to be simple, reproductible, and without great complication. These criteria match well the surgical management of this deformity, which is mainly aesthetic. Moreover, the secondary benefit of liposuction of disgracious steatomery helps the acceptance of the procedure. Therefore in our hands, fat grafting to the breast (lipomodeling) is now our first choice treatment in thoracic Poland syndrome deformity. Given the rarity of this syndrome, we recommend a treatment by an operator who makes the learning curve of lipomodeling, and who often deals with Poland syndrome. PMID:23153632

La Marca, S; Delay, E; Toussoun, G; Ho Quoc, C; Sinna, R

2012-11-12

64

[Subependymal giant cell astrocytoma in patients with tuberous sclerosis: magnetic resonance imaging findings in ten cases].  

UK PubMed Central (United Kingdom)

OBJECTIVE: To report the magnetic resonance imaging (MRI) findings in 10 patients with subependimal giant cell astrocytoma (SGCA) and tuberous sclerosis (TS). METHOD: Ten patients were retrospectively studied, presenting TS and histologically proven SGCA. Four patients were male and six female, with mean age 15.7 years. All patients underwent MRI, which was analyzed by two radiologists, final diagnosis was reached by consensus. The following findings were studied: topography, size, signal intensity on T1/T2-weighted images, contrast enhancement and associated findings. RESULTS: All patients presented a single lesion suggestive of SGCA, measuring between 1.5 cm and 8 cm in the largest diameter. Eight lesions were found near the foramen of Monro and two in the body of the lateral ventricles. The tumors showed preferentially intermediate signal on T1 (70%), high signal on T2-weighted images (100%), with intense enhancement after contrast administration (100%). CONCLUSION: SGCA in patients with TS usually presents as a single lesion near the foramen of Monro, with intermediate signal on T1, high signal on T2-weighted images and intense contrast enhancement.

Takata K; Gasparetto EL; Leite Cda C; Lucato LT; Reed UC; Matushita H; Aguiar PH; Rosemberg S

2007-06-01

65

The Big Ten Student Suicide Study: a 10-year study of suicides on midwestern university campuses.  

UK PubMed Central (United Kingdom)

The Big Ten Student Suicide Study was undertaken from 1980-1990 to determine the suicide rates on Big Ten University campuses. The study design attempted to address many of the statistical and epidemiological flaws identified in previous studies of campus student suicides. The 10-year study collected demographic and correlational data on 261 suicides of registered students at 12 midwestern campuses. The largest number of suicides for both males and females were in the 20-24-year-old age group (46%), and amongst graduate students (32%). The overall student suicide rate of 7.5/100,000 is one half of the computed national suicide rate (15.0/100,000) for a matched sample by age, gender, and race. Despite the overall lower suicide rate, the analyses revealed that students 25 and over have a significantly higher risk than younger students. Although women have rates roughly half those of men throughout their undergraduate years, graduate women have rates not significantly different from their male counterparts (graduate women 9.1/100,000 and graduate men 11.6/100,000).

Silverman MM; Meyer PM; Sloane F; Raffel M; Pratt DM

1997-01-01

66

The Big Ten Student Suicide Study: a 10-year study of suicides on midwestern university campuses.  

Science.gov (United States)

The Big Ten Student Suicide Study was undertaken from 1980-1990 to determine the suicide rates on Big Ten University campuses. The study design attempted to address many of the statistical and epidemiological flaws identified in previous studies of campus student suicides. The 10-year study collected demographic and correlational data on 261 suicides of registered students at 12 midwestern campuses. The largest number of suicides for both males and females were in the 20-24-year-old age group (46%), and amongst graduate students (32%). The overall student suicide rate of 7.5/100,000 is one half of the computed national suicide rate (15.0/100,000) for a matched sample by age, gender, and race. Despite the overall lower suicide rate, the analyses revealed that students 25 and over have a significantly higher risk than younger students. Although women have rates roughly half those of men throughout their undergraduate years, graduate women have rates not significantly different from their male counterparts (graduate women 9.1/100,000 and graduate men 11.6/100,000). PMID:9357084

Silverman, M M; Meyer, P M; Sloane, F; Raffel, M; Pratt, D M

1997-01-01

67

A pilot study on using acupuncture and transcutaneous electrical nerve stimulation (TENS) to treat knee osteoarthritis (OA)  

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Abstract Background The present study tests whether a combined treatment of acupuncture and transcutaneous electrical nerve stimulation (TENS) is more effective than acupuncture or TENS alone for treating knee osteoarthritis (OA). Methods Thirty-two patients with knee ...

Itoh Kazunori; Hirota Satoko; Katsumi Yasukazu; Ochi Hideki; Kitakoji Hiroshi

68

Charnley total hip arthroplasty. A ten- to 14-year follow-up study.  

Science.gov (United States)

The long-term results of 325 consecutive Charnley total hip arthroplasties (THAs) were assessed at an average of 62 and 140 months (five-year and ten-year follow-up examinations) postoperatively. Cases developing deep infection during the first five years were not included. Pain, walking ability, and mobility were rated as advocated by Charnley. The results were then graded as excellent, good, fair (clinically successful), and failure. At the five-year follow-up evaluation, 77 hips were excluded; 92% (228/248) of the results were successful. At the ten-year follow-up examination, interest was focused on the 228 hips graded as successful after five years. Sixty-six were excluded, one that had not been included at the five-year evaluation was traced, and 92% (150/163) were again clinically successful. The failure rate owing to mechanical causes during the first five years and between the five-year and ten-year follow-up examinations was 6.9% and 6.7%, respectively. The clinical results were considered highly satisfactory because only 50% of the hips judged successful at the ten-year examination had roentgenographically intact components. There is good reason to have great confidence in the Charnley THA. PMID:3370865

Wejkner, B; Stenport, J

1988-06-01

69

Charnley total hip arthroplasty. A ten- to 14-year follow-up study.  

UK PubMed Central (United Kingdom)

The long-term results of 325 consecutive Charnley total hip arthroplasties (THAs) were assessed at an average of 62 and 140 months (five-year and ten-year follow-up examinations) postoperatively. Cases developing deep infection during the first five years were not included. Pain, walking ability, and mobility were rated as advocated by Charnley. The results were then graded as excellent, good, fair (clinically successful), and failure. At the five-year follow-up evaluation, 77 hips were excluded; 92% (228/248) of the results were successful. At the ten-year follow-up examination, interest was focused on the 228 hips graded as successful after five years. Sixty-six were excluded, one that had not been included at the five-year evaluation was traced, and 92% (150/163) were again clinically successful. The failure rate owing to mechanical causes during the first five years and between the five-year and ten-year follow-up examinations was 6.9% and 6.7%, respectively. The clinical results were considered highly satisfactory because only 50% of the hips judged successful at the ten-year examination had roentgenographically intact components. There is good reason to have great confidence in the Charnley THA.

Wejkner B; Stenport J

1988-06-01

70

Ten cases of metastatic cervical cancer with the treatment of permanent 125I seeds interstitial implants  

International Nuclear Information System (INIS)

[en] Objective: To investigate the clinical effect of permanent 125I seeds interstitial implants for metastatic cervical cancer. Methods: Under the guidance of the B-sonography, 125I seeds were implanted into the eleven cervical lymph nodes of ten patients who had been given tumor resection. The pain relief and tumor size were observed in regular follow-up after one-month treatment. Results: All the patients were followed up for 6-14 months,and the postoperative recovery was good with no complication. One month after the implantation, the pain symptom was alleviated entirely in two nodes and partly in nine nodes. The tumor size shrank in ten nodes while there was no change in one node after one month. Conclusion: Permanent 125I seeds interstitial implants for metastatic cervical cancer is a safe, minimally invasive and effective treatment. (authors)

2011-01-01

71

Childhood poisoning in Warri, Niger Delta, Nigeria: A ten year retrospective study  

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Full Text Available Background: Childhood poisoning is a common but avoidable problem in developingcountries such as Nigeria.Objectives: To determine the pattern of childhood poisoning in the Warri Niger Delta Regionof Nigeria.Method: The case notes of all the children seen at Central Hospital Warri, the reference basefor the region and GN Children Clinic the pioneer children’s hospital in the region. This isa review of cases over a ten year period, from 2000 to 2009. The information obtained wasanalysed.Results: A total of 156 children aged 0–16 years diagnosed with poisoning were seen at thecentral hospital in Warri and at the GN Children’s Clinic which is also in Warri over a 10year period from 2000 to 2009 under review. The male to female ratio is 2:1, and 75% of thechildren were aged 5 years or less. Most of the patients were from the low socio-economicclass. Most of the poisoning was unintentional and occurred through ingestion (97.6%).Kerosene was the major substance leading to poisoning (56.6%). Alcohol ranked second inthe study. Poisoning from drugs was the third most common source of poisoning and inthat category most of the indices were in the highest income group. Most of the patientspresented with mild symptoms and the mortality rate was 7%.Conclusion: Kerosine was found to be the most common source of poisoning. Most of thepoisoning was unintensional and deaths cause by this form of poisoning can be preventedwith proper health education and effective enactment of laws that will reduce the incidenceof childhood poisoning.

Gilbert IM. Ugwu; Blessing O. Okperi; Eunice N. Ugwu; Nekwu E. Okolugbo

2012-01-01

72

The Pancreatic Cancer Cases in Dicle University Department of Gastroenterology in the Last Ten Years  

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Full Text Available Pancreatic cancer is the second most frequent gastrointestinal malignancy,with an extremely poor prognosis. There is a few data about frequency ofpancreatic cancer in our country. We evaluate the general features of these patientswho diagnosed in Gastroenterology clinic, University of Dicle within last 10 years.There were 55 patients in our study who obtained by screening the past files fromlast 10 years’ registry.The gender disturbance was 64% male and 36% female in our pancreaticcancer patients with a male-to-female ratio of 1.75 / 1 . The overall median age was59.9 years. Of the cases 89% were equal or above 45 years old. The most frequentsymptoms were abdominal pain (89%) and weight loss (85%). There were ichterusin 49%, epigasrical mass in 20% and ascitic fluid in 10% of the patients. Sixtypercent were heavy smokers, and 16% of them had cholecystectomy history. Newonsetdiabetes mellitus observed in 36% patients. Of the cases 93% were in highstage (III-IV). Disease which observed in advanced age and had male dominance,must be kept in mind as an entity in case of new-onset diabetes mellitus andgastrointestinal alarm symptoms

Ramazan Dan?s; Kadim Bayan; Serif Y?lmaz; Abdullah Alt?ntas

2004-01-01

73

Reassessing "Jacob's case": a serial killer re-examined after ten years.  

UK PubMed Central (United Kingdom)

The current study re-examines an exceptional case of a serial killer incarcerated since a decade ago. "Jacob" is the first serial killer apprehended in Israel. His known actions were committed during the eighties of the last century, and continued for eleven years. The victims were elderly individuals, including both his parents. Shortly after incarceration he became overtly schizophrenic and underwent five hospitalisations. The case is re-examined in view of changes, both in the perpetrator's diagnosis and criminal legislation. Was Jacob doomed to become a serial killer, or could his fate be avoided through early professional intervention? Were the killings presenting symptoms of a psychotic or pre-psychotic phase? Should he be eligible for a retrial? What would have been his position with the current law in view of the new 300A(a) clause ("Reduced Punishment") of the Israeli Criminal Code? Could he ever be released back to the community? These are some of the questions to be addressed.

Kalian M; Birger M; Witztum E

2004-01-01

74

Reassessing "Jacob's case": a serial killer re-examined after ten years.  

Science.gov (United States)

The current study re-examines an exceptional case of a serial killer incarcerated since a decade ago. "Jacob" is the first serial killer apprehended in Israel. His known actions were committed during the eighties of the last century, and continued for eleven years. The victims were elderly individuals, including both his parents. Shortly after incarceration he became overtly schizophrenic and underwent five hospitalisations. The case is re-examined in view of changes, both in the perpetrator's diagnosis and criminal legislation. Was Jacob doomed to become a serial killer, or could his fate be avoided through early professional intervention? Were the killings presenting symptoms of a psychotic or pre-psychotic phase? Should he be eligible for a retrial? What would have been his position with the current law in view of the new 300A(a) clause ("Reduced Punishment") of the Israeli Criminal Code? Could he ever be released back to the community? These are some of the questions to be addressed. PMID:15163076

Kalian, M; Birger, M; Witztum, E

2004-01-01

75

Purple urine bag syndrome in nursing homes: Ten elderly case reports and a literature review  

Directory of Open Access Journals (Sweden)

Full Text Available Chi-Hung Lin1, Hsien-Te Huang1, Chia-Chang Chien1, Dong-Sheng Tzeng1,2, For-Wey Lung1,3–51Department of Psychiatry, Kaohsiung Armed Forces General Hospital, Kaohsiung, Taiwan; 2Graduate Institute of Occupational Safety and Health; 3Graduate Institute of Behavioral Sciences, Kaohsiung Medical University, Kaohsiung, Taiwan; 4Department of Psychiatry, National Defense Medical Center, Taipei, Taiwan; 5Calo Psychiatric Center, Pingtung County, TaiwanAbstract: Purple urine bag syndrome (PUBS) is a rare occurrence, in which the patient has a purple-colored urine bag following urinary catheterization for hours to days. Most of authors believe it is a mixture of indigo (blue) and indirubin (red) that becomes purple. Previous study showed that PUBS occurred predominantly in chronically catheterized, constipated women. We collected 10 elderly patients with PUBS in two nursing homes. The first two cases were identified by chart review in 1987 and 2003, and then later eight cases (42.1%) were collected among 19 urinary catheterized elderly in the period between January 2007 and June 2007. In the present report, PUBS probably can occur in any patients with the right elements, namely urinary tract infection (UTI) with bacteria possessing these enzymes, diet with enough tryptophan, and being catheterized. Associations with bed-bound state, Alzheimer’s, or dementia from other causes are reflections of the state of such patients who are at higher risk for UTI, and hence PUBS occurred. Although we presented PUBS as a harmless problem, prevention and control of the nosocomial catheter-associated UTIs (CAUTIs) has become very important in the new patient-centered medical era. Thus, we should decrease the duration of catheterization, improve catheter care, and deploy technological advances designed for prevention, especially in the elderly cared for in nursing homes.Keyword: purple urine bag syndrome, indigo, indirubin, nursing home, bacteriuria, indoxyl sulphatase/phosphatase, nosocomial catheter-associated UTIs

Chi-Hung Lin; Hsien-Te Huang; Chia-Chang Chien; Dong-Sheng Tzeng; For-Wey Lung

2008-01-01

76

Children's perceptions of negative events in Northern Ireland: a ten year study.  

UK PubMed Central (United Kingdom)

This study examines changes in Northern Irish children's perceptions of negative events over ten years. Ten year old children's perceptions of potentially distressing situations were obtained from two groups of children in 1983 and 1994 using a 25 item self-report measure. The children's perceptions of the events are contrasted across time and also comparisons between socioeconomic and religious groups are made. The comparison shows that the children's perceptions of the events remains relatively constant across time, with certain events being consistently viewed as the most stressful and least stressful across time and between groups. Comparison of religious and socioeconomic groups suggests that working class and Roman Catholic children in Northern Ireland frequently rate negative events as more stressful than others in their cohort.

Muldoon OT; Trew K; McWhirter L

1998-03-01

77

CASE STUDY CRITIQUE; UPPER CLINCH CASE STUDY  

Science.gov (United States)

Case study critique: Upper Clinch case study (from Research on Methods for Integrating Ecological Economics and Ecological Risk Assessment: A Trade-off Weighted Index Approach to Integrating Economics and Ecological Risk Assessment). This critique answers the questions: 1) does ...

78

Cutaneous epithelioid angiomatous nodule: different views or interpretations in the analysis of ten new cases.  

UK PubMed Central (United Kingdom)

Classification schemes proposed for vascular lesions are the subjects of significant controversy. Cutaneous epithelioid angiomatous nodule (CEAN) was described in 2004, but there is no agreement as to whether this is a distinct entity or a type of either epithelioid hemangioma or angiolymphoid hyperplasia with eosinophilia. We present a typical case of CEAN and discuss nine other cases from our institution. We then provide two opposing viewpoints concerning its classification.

Al-Daraji WI; Prescott RJ; Abdellaoui A; Khan MM; Kulkarni K; Youssef MM; Zelger BG; Zelger B

2009-01-01

79

[Vertical maternal fetal transmission of the chikungunya virus. Ten cases among 84 pregnant women].  

UK PubMed Central (United Kingdom)

INTRODUCTION: In March 2005, an epidemic of chikungunya virus began in the southern portion of Reunion Island (French overseas district in the Indian Ocean) and spread to the northern part of the island at the end of 2005. The Reunion-South Hospital Group observed the first cases of pregnant women infected with the virus in June 2005. We report here for the first time maternal-fetal transmission of this virus. CASES: From June 2005 through the end of January 2006, 84 pregnant women had acute chikungunya infections during pregnancy. In 88% of these cases (n=74)--all involving infections relatively distant from delivery--the newborns appeared asymptomatic. Conversely, 10 newborns had severe attacks (4 with meningoencephalitis and 3 with intravascular coagulations) after birth and required prolonged neonatal hospitalization (6 in the neonatal intensive care unit with intubation and assisted ventilation). No infants died, but there was one case of severe intracerebral hemorrhage after severe thrombocytopenia. These cases were confirmed by specific serology testing or PCR or both for mothers and newborns. We note that all severe cases involved women with viremia and fever in the intrapartum period.

Robillard PY; Boumahni B; Gérardin P; Michault A; Fourmaintraux A; Schuffenecker I; Carbonnier M; Djémili S; Choker G; Roge-Wolter M; Barau G

2006-05-01

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Pharmacological Studies of Ten Medicinal Plants Used for Analgesic Purposes in Congo Brazzaville  

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Full Text Available The aim of this study was to assess ten plants from the Congolese pharmacopoeia for their analgesic activity as well as their cytotoxicity, in order to validate their traditional use. Thirty-three extracts were obtained in 3 different solvents (Water, Ethanol, DCM) from these ten plants selected after an ethnobotanic survey in the region of the Pool (Congo Brazzaville): Leonotis nepetaefolia (Lamiaceae), Manotes pruinosa (Connaraceae), Spilanthes uliginosa (Asteraceae), Hymenocardia ulmoides (Euphorbiaceae), Celosia trigyna (Amaranthaceae), Cogniauxia podolaena (Cucurbitaceae), Brillantaisia patula (Acanthaceae), Urena lobata (Malvaceae) , Mitracarpus scaber (Rubiaceae), Triumfetta rhomboidea (Tiliaceae). The writhing test (Siegmund Chemical Test) was used for the pharmacological screening. The cytotoxicity of all the extracts was tested on KB (Human epidermoid carcinoma) and Vero (African green monkey kidney) cell lines with taxotere as positive control. A TLC chemical screening of the extracts was carried out to detect the major chemical classes present in the plants. The data of the traditional medicine were confirmed, since eight plants out of ten were active, aqueous and ethanolic extracts being the most active. Moreover, only C. podolaena leaf extracts were cytotoxic (87% of inhibition on KB). This work opens the way for the research of the active molecules from these plants and for their use as leads in the synthesis and the pharmacomodulation of compounds with analgesic potentiality.

Marie-Claire Makambila-Koubemba; Bernard Mbatchi; Denis Ardid; Agathe Gelot; Cindy Henrion; Robin Janisson; Ange A. Abena; Jean-Theophile Banzouzi

2011-01-01

 
 
 
 
81

Sarcomatoid carcinoma of the renal pelvis: Experience of multiple cases over a ten-year period.  

UK PubMed Central (United Kingdom)

Sarcomatoid carcinoma of the renal pelvis is a rare clinical entity. To the best of our knowledge, only 14 cases of this type of neoplasm have been reported in the literature to date. In the present study, the records at The First Affiliated Hospital, Medicine School of Zhejiang University (Hangzhou, Zhejiang, China) between 2000 and 2010 were reviewed to identify patients with primary renal pelvis sarcomatoid carcinoma (RPSC). A particular emphasis was placed on the treatment, recurrence and survival outcome. Eight patients with RPSC were identified and treated with nephrectomy or nephroureterectomy. All of the patients presented with Grade 3 RPSC. According to the TNM classification system, 2 patients were in stage pT2, 5 in stage pT3 and 1 in stage pT4. Adjuvant chemotherapy was administered to four patients, and the mean follow-up period was 27.5±41.0 months. In total, 6 patients succumbed to the disease with a mean survival time of 7.7±5.3 months (range, 1-18 months), while 2 patients were free of disease at 54 and 120 months, respectively, following treatment. The mean disease-specific survival time was 27.5±41.0 months and the 1-year recurrence-free survival, 1-year survival and overall survival rates were 37.5, 37.5 and 25%, respectively. The present analysis suggests a poor prognosis for the majority of RPSC patients, most likely resulting from the advanced stage of the disease at diagnosis and a poor response to systemic therapy. To improve the survival rate of RPSC, it is therefore essential to perform an early diagnosis and early radical surgery. Intravesical instillation is not essential following surgery.

Chen S; Chen G; Xia D; Li J; Wang S; Shen B; Jin B

2013-08-01

82

Mucinous carcinoid of the ovary: report of a case with metastasis in the contralateral ovary after ten years  

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Full Text Available Monodermal teratomas of the ovary can take the form of carcinoid tumors of which there are several types, mucinous carcinoid being the least common. Very few cases of primary mucinous carcinoid of the ovary have been reported in the literature and the behavior of these tumors over the long term is unclear. We describe a case of primary mucinous carcinoid of the ovary in a 39-year-old woman treated with unilateral salpingo-oophorectomy, where a metastasis occurred in the contralateral ovary ten years later. This case demonstrates that mucinous carcinoid of the ovary can metastasize even after a long interval, and careful follow-up of patients, particularly those treated conservatively, is appropriate.

Christien Buis; Helena C. van Doorn; Winand N.M. Dinjens; Patricia C. Ewing

2010-01-01

83

Tubulo-squamous polyp: a report of ten cases of a distinctive hitherto uncharacterized vaginal polyp.  

UK PubMed Central (United Kingdom)

We report 10 cases of a morphologically distinct vaginal polyp which has hitherto not been characterized. The polyps occurred in women aged 39 to 78 years (most were postmenopausal) and were from 1.0 to 3.0 cm. Most of whose location is known to us were in the upper vagina. Histologically, all the polyps were remarkably similar and composed of well-circumscribed expansile nests of epithelial cells embedded in a hypocellular fibrous stroma. The epithelial elements, which were morphologically bland, were predominantly glycogenated or nonglycogenated squamous in type but small tubules were present at the periphery of some of the nests in all cases. Some of the squamous nests exhibited central necrosis with or without calcification and, in 3 cases, some contained keratin pearls. In 3 cases, a few tubules unassociated with squamous elements were present. In 3 of 4 cases tested, the cells lining the tubules were positive with prostatic acid phosphatase and in 2 of 4 with prostate-specific antigen. The epithelial elements reacted with broad-spectrum cytokeratins and cytokeratin 7 but the mesenchymal component was negative. The squamous elements were estrogen receptor positive and the mesenchymal component estrogen and progesterone receptor positive. The histologic features of this polyp, which we term "tubulo-squamous polyp of the vagina," are constant and distinctive and differ from other polyps and from mixed tumor of the vagina. Several cases reported in the literature as vaginal mixed tumor or Brenner tumor are likely examples of this entity. Possible theories of histogenesis include a Mullerian origin, derivation from mesonephric remnants or derivation from urogenital sinus-derived epithelium. Positive staining in some cases with prostatic acid phosphatase and prostate-specific antigen raises the possibility of ectopic prostatic tissue, although the overall appearance is different from that entity, or derivation from paraurethral Skene glands, the female equivalent of prostatic glands in the male.

McCluggage WG; Young RH

2007-07-01

84

Tubulo-squamous polyp: a report of ten cases of a distinctive hitherto uncharacterized vaginal polyp.  

Science.gov (United States)

We report 10 cases of a morphologically distinct vaginal polyp which has hitherto not been characterized. The polyps occurred in women aged 39 to 78 years (most were postmenopausal) and were from 1.0 to 3.0 cm. Most of whose location is known to us were in the upper vagina. Histologically, all the polyps were remarkably similar and composed of well-circumscribed expansile nests of epithelial cells embedded in a hypocellular fibrous stroma. The epithelial elements, which were morphologically bland, were predominantly glycogenated or nonglycogenated squamous in type but small tubules were present at the periphery of some of the nests in all cases. Some of the squamous nests exhibited central necrosis with or without calcification and, in 3 cases, some contained keratin pearls. In 3 cases, a few tubules unassociated with squamous elements were present. In 3 of 4 cases tested, the cells lining the tubules were positive with prostatic acid phosphatase and in 2 of 4 with prostate-specific antigen. The epithelial elements reacted with broad-spectrum cytokeratins and cytokeratin 7 but the mesenchymal component was negative. The squamous elements were estrogen receptor positive and the mesenchymal component estrogen and progesterone receptor positive. The histologic features of this polyp, which we term "tubulo-squamous polyp of the vagina," are constant and distinctive and differ from other polyps and from mixed tumor of the vagina. Several cases reported in the literature as vaginal mixed tumor or Brenner tumor are likely examples of this entity. Possible theories of histogenesis include a Mullerian origin, derivation from mesonephric remnants or derivation from urogenital sinus-derived epithelium. Positive staining in some cases with prostatic acid phosphatase and prostate-specific antigen raises the possibility of ectopic prostatic tissue, although the overall appearance is different from that entity, or derivation from paraurethral Skene glands, the female equivalent of prostatic glands in the male. PMID:17592267

McCluggage, W Glenn; Young, Robert H

2007-07-01

85

Cancer profile in the Department of Pathology of Sri Devaraj Urs Medical College, Kolar: a ten years study.  

UK PubMed Central (United Kingdom)

CONTEXT: Cancer profile varies in different regions and depends on race, lifestyle and diet. The study of a cancer profile helps to know the common cancers in a particular population, its probable risk factors and also helps in cancer control programs. AIM: To study the cancer profile at Kolar, based on Pathology Department records. SETTINGS AND DESIGN: Retrospective study from January 1997 to December 2006. MATERIALS AND METHODS: Cancer cases diagnosed by fine needle aspiration cytology (FNAC) and histopathology in the Department of Pathology were included in the study. The relevant history, clinical findings, and sociodemographic information of each case was retrieved from hospital records. Statistical Analysis Used: Descriptive statistics. RESULTS: Out of a total of 19,615 cases reported at the Department of Pathology, 2,744 (13.98%) were cancer cases. The peak incidence was in the fifth decade in females and the seventh decade in males. Male : Female ratio was 0.7 : 1. Overall there was a steady rise in the number of cases from year 1997 to 2006. The top ten cancers in males were of oral cavity, stomach, esophagus, bone, non-Hodgkin's lymphoma (NHL), prostate, liver, larynx, penis, and Hodgkin's disease / bladder and those in females were oral cavity, cervix, breast, stomach, esophagus, thyroid, ovary, bone, rectum, and melanoma. CONCLUSIONS: Oral cavity and upper gastrointestinal cancers predominated in both genders. In females, cervical cancer predominated over breast cancer. Thyroid cancers were relatively more common in this region especially in females.

Kalyani R; Das S; Bindra Singh MS; Kumar H

2010-04-01

86

In vitro antimicrobial activity of ten medicinal plants against clinical isolates of oral cancer cases.  

UK PubMed Central (United Kingdom)

BACKGROUND: Suppression of immune system in treated cancer patients may lead to secondary infections that obviate the need of antibiotics. In the present study, an attempt was made to understand the occurrence of secondary infections in immuno-suppressed patients along with herbal control of these infections with the following objectives to: (a) isolate the microbial species from the treated oral cancer patients along with the estimation of absolute neutrophile counts of patients (b) assess the in vitro antimicrobial activity medicinal plants against the above clinical isolates. METHODS: Blood and oral swab cultures were taken from 40 oral cancer patients undergoing treatment in the radiotherapy unit of Regional Cancer Institute, Pt. B.D.S. Health University,Rohtak, Haryana. Clinical isolates were identified by following general microbiological, staining and biochemical methods. The absolute neutrophile counts were done by following the standard methods. The medicinal plants selected for antimicrobial activity analysis were Asphodelus tenuifolius Cav., Asparagus racemosus Willd., Balanites aegyptiaca L., Cestrum diurnum L., Cordia dichotoma G. Forst, Eclipta alba L., Murraya koenigii (L.) Spreng. , Pedalium murex L., Ricinus communis L. and Trigonella foenum graecum L. The antimicrobial efficacy of medicinal plants was evaluated by modified Kirby-Bauer disc diffusion method. MIC and MFC were investigated by serial two fold microbroth dilution method. RESULTS: Prevalent bacterial pathogens isolated were Staphylococcus aureus (23.2%), Escherichia coli (15.62%), Staphylococcus epidermidis (12.5%), Pseudomonas aeruginosa (9.37%), Klebsiella pneumonia (7.81%), Proteus mirabilis (3.6%), Proteus vulgaris (4.2%) and the fungal pathogens were Candida albicans (14.6%), Aspergillus fumigatus (9.37%). Out of 40 cases, 35 (87.5%) were observed as neutropenic. Eight medicinal plants (A. tenuifolius, A. racemosus, B. aegyptiaca, E. alba, M. koenigii, P. murex R. communis and T. foenum graecum) showed significant antimicrobial activity (P < .05) against most of the isolates. The MIC and MFC values were ranged from 31 to 500 ?g/ml. P. aeruginosa was observed highest susceptible bacteria (46.6%) on the basis of susceptible index. CONCLUSION: It can be concluded that treated oral cancer patients were neutropenic and prone to secondary infection of microbes. The medicinal plant can prove as effective antimicrobial agent to check the secondary infections in treated cancer patients.

Panghal M; Kaushal V; Yadav JP

2011-01-01

87

Thrombolytic therapy for early postoperative pulmonary embolism: a report of ten cases  

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Full Text Available Objective ?To investigate the feasibility of thrombolytic therapy for early postoperative pulmonary embolism, and the choice of thrombolytic drug, and its dosage and administration route. Methods ?A retrospective analysis of the clinical data of 10 patients with early acute pulmonary embolism undergoing thrombolytic therapy in our department from 1999 to 2011 was performed, followed by a review of related literature in China and abroad, the experience of the diagnosis and treatment were summarized. Results ?The diagnosis of 10 cases of acute pulmonary embolism were doubtless. After diagnosis, immediate early thrombolytic therapy was given, including 7 cases of central venous thrombolysis, 2 cases of peripheral intravenous thrombolysis, and 1 case with interventional thrombectomy plus thrombolytic therapy. The treatment was successful in all the patients, with earliest effective time at 30min. After the treatment, and latest improvement in oxygenation at 12 hours. Nine patients were cured, in 5 patients it was complicated by local bleeding, and 1 patient died of infectious complication. Conclusions ?Prudent thrombolytic therapy is safe, feasible and effective in the treatment of early postoperative pulmonary embolism.

Xiong-long ZHU; Wen-bin HAN; Tao ZHENG; Shi-hong ZHU; Jin-yong SUN

2012-01-01

88

A ten year (1999-2008) retrospective study of amoebiasis in University Malaya Medical Centre (UMMC), Kuala Lumpur, Malaysia.  

UK PubMed Central (United Kingdom)

This is a ten year (1999-2008) retrospective study of amebiasis in patients admitted to UMMC. A total of 34 cases were analyzed. The most common were amebic liver abscess 22(65%) and the rest were amoebic dysentery 12(35%). Majority of the cases occurred among Malaysians 29(85%), with Chinese 14(41%), followed by the Malays 9(26%) and the Indians 6(18%). Foreigners made up of one Indonesian, one Pakistani and three Myanmarese and constituted 5(15%) of the total cases. Males 24(71%) were more commonly affected. Most of the cases occurred between the age group of 40-49 years, 8(23%) and 60 years and above, 8(23%). Age group of 20-50 years constituted 20(60%) of the cases. The most common clinical presentations were fever with chills and rigors 26(76%), diarrhoea 20 (59%), right hypochondrium pain 17(50%), abdominal pain 17(50%), hepatomegaly 16 (47%) and jaundice 7(20%). All were discharged well after treatment except for one case of death in a 69-year-old Chinese male with amebic liver abscess.

Farhana F; Jamaiah I; Rohela M; Abdul-Aziz NM; Nissapatorn V

2009-12-01

89

A pilot study on using acupuncture and transcutaneous electrical nerve stimulation (TENS) to treat knee osteoarthritis (OA)  

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Full Text Available Abstract Background The present study tests whether a combined treatment of acupuncture and transcutaneous electrical nerve stimulation (TENS) is more effective than acupuncture or TENS alone for treating knee osteoarthritis (OA). Methods Thirty-two patients with knee OA were randomly allocated to four groups. The acupuncture group (ACP) received only acupuncture treatment at selected acupoints for knee pain; the TENS group (TENS) received only TENS treatment at pain areas; the acupuncture and TENS group (A&T) received both acupuncture and TENS treatments; the control group (CT) received topical poultice (only when necessary). Each group received specific weekly treatment five times during the study. Outcome measures were pain intensity in a visual analogue scale (VAS) and knee function in terms of the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Results The ACP, TENS and A&T groups reported lower VAS and WOMAC scores than the control group. Significant reduction in pain intensity (P = 0.039) and significant improvement in knee function (P = 0.008) were shown in the A&T group. Conclusion Combined acupuncture and TENS treatment was effective in pain relief and knee function improvement for the sampled patients suffering from knee OA.

Itoh Kazunori; Hirota Satoko; Katsumi Yasukazu; Ochi Hideki; Kitakoji Hiroshi

2008-01-01

90

Goodpasture's disease: A report of ten cases and a review of the literature.  

Science.gov (United States)

This review is based on our experience with ten patients diagnosed with Goodpasture's disease (GD). Six of the patients presented with combined renal and pulmonary insufficiencies; in the remaining four patients the clinical findings were limited to renal involvement. Circulating anti-glomerular basement membrane (GBM) autoantibodies were detected at diagnosis in all patients. Two patients were double-positive for anti-GBM and anti-proteinase-3 neutrophil cytoplasmic antibodies (c-ANCA). Another patient was double positive for anti-GBM and anti-myeloperoxidase cytoplasmic antibodies (p-ANCA). Four patients with rapidly progressive glomerulonephritis underwent hemodialysis: two of these patients died 6 and 8months after diagnosis, and the other two required maintenance dialysis. The remaining six patients were administered variable combinations of plasma-exchange, corticosteroids, and immunosuppressive drugs, which resulted in a remarkable and progressive improvement in renal function and one-year renal survival in all of them. Building on these observations, we provide an update on this relatively rare, frequently severe, and sometimes lethal autoimmune disease of unknown etiology. GD patients typically present with rapidly progressive renal insufficiency and pulmonary hemorrhage. Involvement restricted to the kidneys alone, as in our series, is also seen. The unfailing immunological hallmark of the disease is the occurrence of circulating anti-GBM antibodies, whose titer is directly related to the clinical severity of GD. The antibodies are associated with serum ANCAs in 10% to almost 40% of GD patients, with double positivity indicative of a worse renal prognosis. The target antigen of anti-GBM antibodies is a component of the non-collagenous-1 (NC1) domain of the ?3 chain of type IV collagen, ?345NC1. The prevalent expression of this hexamer on the basement membrane of both the glomeruli and the pulmonary alveoli accounts for the frequently combined renal and pulmonary involvement. A strong positive association of GD with the HLA-DRB1*15:01 allele has been described, but the factor(s) responsible for the loss of self-tolerance to NC1 autoantigen has not yet been identified. A conformational change in the quaternary structure of the ?345NC1 likely plays a crucial role in triggering an immune response and justifies the proposed description of GD as an autoimmune "conformeropathy." The function of autoreactive T-cells in GD is poorly defined but may involve a shift from TH2 to TH1 cytokine regulation, such that affinity maturation and the antigen specificity of the antibody response are enhanced. The timely diagnosis of GD and the adoption of a triple therapeutic regimen comprising plasmapheresis, corticosteroids, and immunosuppressive drugs have remarkably improved the previously dismal outcome of these patients, resulting in a one-year survival rate of 70-90%. PMID:23806563

Dammacco, Franco; Battaglia, Stefano; Gesualdo, Loreto; Racanelli, Vito

2013-06-24

91

Intrascrotal lipoblastoma in a ten year old boy: case report and review of literature  

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Full Text Available Lipoblastoma is a rare benign soft tissue tumor encountered almost exclusively in infancy and early childhood. The location of tumors varies, but most occur in the extremities, trunk, head and neck. Less frequently, lipoblastomas have been reported in the mediastinum, the retroperitoneum and the inguinal region. Only 7 cases of lipoblastoma in the scrotum have been reported so far in the English literature, with none of the patients older than 8. We report an intrascrotal lipoblastoma in a 10 year-old boy. The differential diagnosis is discussed with reference to the literature.

Ghassan Nakib; Valeria Calcaterra; Luigi Avolio; Marinella Guazzotti; Ilaria Goruppi; Alessandra Viglio; Gloria Pelizzo

2013-01-01

92

Intrascrotal lipoblastoma in a ten year old: case report and review of literature.  

Science.gov (United States)

Lipoblastoma is a rare benign soft tissue tumor encountered almost exclusively in infancy and early childhood. The location of tumors varies, but most occur in the extremities, trunk, head and neck. Less frequently, lipoblastomas have been reported in the mediastinum, the retroperitoneum and the inguinal region. Only 7 cases of lipoblastoma in the scrotum have been reported so far in the English literature, with none of the patients older than 8. We report an intrascrotal lipoblastoma in a 10 year-old boy. The differential diagnosis is discussed with reference to the literature. PMID:23772297

Nakib, Ghassan; Calcaterra, Valeria; Avolio, Luigi; Guazzotti, Marinella; Goruppi, Ilaria; Viglio, Alessandra; Pelizzo, Gloria

2013-03-12

93

Intrascrotal lipoblastoma in a ten year old: case report and review of literature.  

UK PubMed Central (United Kingdom)

Lipoblastoma is a rare benign soft tissue tumor encountered almost exclusively in infancy and early childhood. The location of tumors varies, but most occur in the extremities, trunk, head and neck. Less frequently, lipoblastomas have been reported in the mediastinum, the retroperitoneum and the inguinal region. Only 7 cases of lipoblastoma in the scrotum have been reported so far in the English literature, with none of the patients older than 8. We report an intrascrotal lipoblastoma in a 10 year-old boy. The differential diagnosis is discussed with reference to the literature.

Nakib G; Calcaterra V; Avolio L; Guazzotti M; Goruppi I; Viglio A; Pelizzo G

2013-02-01

94

Ten years later: an update of the case for teaching breast self-examination.  

Science.gov (United States)

Breast self-examination (BSE) remains an appropriate area for continuing research. Nonetheless, it is now established that instruction by either a nurse or a physician, whether offered individually or in groups, and regardless of the details of the content or the teaching materials used, will result in a reported increase in frequency and proficiency. Less traditional instruction by means of the mass media also has been reported as effective. The actual competence in the practice of BSE remains questionable both because of inconsistency in the standards of practice and of reliance on self-reporting. The ultimate question related to the effectiveness of BSE in detecting tumors at a stage where the diagnosis is favourable remains uncertain. There have been some gains in knowledge during the last decade and the case for teaching BSE remains strong but its effectiveness is not yet unequivocally established. PMID:2282607

Alcoe, S Y; Wallace, D G; Beck, B M

95

Ten years later: an update of the case for teaching breast self-examination.  

UK PubMed Central (United Kingdom)

Breast self-examination (BSE) remains an appropriate area for continuing research. Nonetheless, it is now established that instruction by either a nurse or a physician, whether offered individually or in groups, and regardless of the details of the content or the teaching materials used, will result in a reported increase in frequency and proficiency. Less traditional instruction by means of the mass media also has been reported as effective. The actual competence in the practice of BSE remains questionable both because of inconsistency in the standards of practice and of reliance on self-reporting. The ultimate question related to the effectiveness of BSE in detecting tumors at a stage where the diagnosis is favourable remains uncertain. There have been some gains in knowledge during the last decade and the case for teaching BSE remains strong but its effectiveness is not yet unequivocally established.

Alcoe SY; Wallace DG; Beck BM

1990-11-01

96

Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization.  

DEFF Research Database (Denmark)

Allergen-specific immunoglobulin E (present in allergic sensitization) has a central role in the pathogenesis of allergic disease. We performed the first large-scale genome-wide association study (GWAS) of allergic sensitization in 5,789 affected individuals and 10,056 controls and followed up the top SNP at each of 26 loci in 6,114 affected individuals and 9,920 controls. We increased the number of susceptibility loci with genome-wide significant association with allergic sensitization from three to ten, including SNPs in or near TLR6, C11orf30, STAT6, SLC25A46, HLA-DQB1, IL1RL1, LPP, MYC, IL2 and HLA-B. All the top SNPs were associated with allergic symptoms in an independent study. Risk-associated variants at these ten loci were estimated to account for at least 25% of allergic sensitization and allergic rhinitis. Understanding the molecular mechanisms underlying these associations may provide new insights into the etiology of allergic disease.

BØnnelykke, Klaus; Matheson, Melanie C

2013-01-01

97

Case Studies in Business Ethics  

Science.gov (United States)

The most recent guide from Inc.com offers case studies in business ethics and includes coverage of businesses striving to become more environmentally aware, provide community growth, and activate global change. One of the case studies follows Fetzer Vineyards, a California winery committed to reducing its own waste; another describes the way that the Philadelphia restaurant White Dog Cafe donates ten percent of its $4.4 million profit to a variety of nonprofit organizations. The case studies are generally quite short and easy to read; additionally, they link to several online polls that test users's business ethics skills. For more information on Guides @ Inc.com, see the August 10, 2000 Scout Report for Business and Economics.

98

Case Study Teaching  

Science.gov (United States)

|This chapter describes the history of case study teaching, types of cases, and experimental data supporting their effectiveness. It also describes a model for comparing the efficacy of the various case study methods. (Contains 1 figure.)|

Herreid, Clyde Freeman

2011-01-01

99

Benign fibrous histiocytoma of bone: a report of ten cases and review of literature.  

Science.gov (United States)

The benign fibrous histiocytoma is a rare tumor with only a few descriptions. In order to better define the optimal therapeutic procedure and the necessity of surgery we retrospectively analyzed the patients of the orthopedic department. Benign fibrous histiocytoma occurred in the femur (n = 3), pelvis (n = 2), humerus, tibia, fibula, rib and spine. Pain as the cardinal symptom and a median age of 28 years are factors that differentiate benign fibrous histiocytoma from other metaphyseal fibrous lesions such as the nonossifying fibroma. Radiographic investigation of this entity showed osteolytic lesions with eccentric thinning of the cortex and small fissures. To a variable extent, sclerosis was found in the margin of the lesions. Computer tomography revealed dense soft tissue in the lesions, but one lesion was filled with fluid. The tumor was restricted to bone, with no periosteal or soft tissue reaction. Magnetic resonance imaging showed enhancement of the tumor after administration of contrast medium. All lesions had uniform histological findings. Although no pathologic fracture occurred in any case, local expansion of the tumor was indicated by cortical thinning, small fissures and pain. This implied that the patients needed prophylactic curettage and bone grafting. Surgery restricted to the osteolytic area was sufficient to prevent recurrence. PMID:12407938

Grohs, Josef G; Nicolakis, Michael; Kainberger, Franz; Lang, Susanna; Kotz, Rainer

2002-01-15

100

Benign fibrous histiocytoma of bone: a report of ten cases and review of literature.  

UK PubMed Central (United Kingdom)

The benign fibrous histiocytoma is a rare tumor with only a few descriptions. In order to better define the optimal therapeutic procedure and the necessity of surgery we retrospectively analyzed the patients of the orthopedic department. Benign fibrous histiocytoma occurred in the femur (n = 3), pelvis (n = 2), humerus, tibia, fibula, rib and spine. Pain as the cardinal symptom and a median age of 28 years are factors that differentiate benign fibrous histiocytoma from other metaphyseal fibrous lesions such as the nonossifying fibroma. Radiographic investigation of this entity showed osteolytic lesions with eccentric thinning of the cortex and small fissures. To a variable extent, sclerosis was found in the margin of the lesions. Computer tomography revealed dense soft tissue in the lesions, but one lesion was filled with fluid. The tumor was restricted to bone, with no periosteal or soft tissue reaction. Magnetic resonance imaging showed enhancement of the tumor after administration of contrast medium. All lesions had uniform histological findings. Although no pathologic fracture occurred in any case, local expansion of the tumor was indicated by cortical thinning, small fissures and pain. This implied that the patients needed prophylactic curettage and bone grafting. Surgery restricted to the osteolytic area was sufficient to prevent recurrence.

Grohs JG; Nicolakis M; Kainberger F; Lang S; Kotz R

2002-01-01

 
 
 
 
101

German national case collection for familial pancreatic cancer (FaPaCa): ten years experience.  

UK PubMed Central (United Kingdom)

Familial pancreatic cancer (FPC) is a rare hereditary tumor syndrome. The 10-years experience of the national case collection for familial pancreatic cancer of Germany (FaPaCa) is reported. Since 1999 FaPaCa has collected families with at least two first-degree relatives with confirmed pancreatic cancer (PC), who did not fulfill the criteria of other hereditary tumor syndromes. Histopathological verification of tumor diagnoses, and genetic counseling were prerequisites for enrollment of families in FaPaCa. 94 of 452 evaluated families fulfilled the criteria for partaking in FaPaCa. PC represented the sole tumor entity in 38 (40%) families. In 56 families additional tumor types occurred, including breast cancer (n = 28), colon cancer (n = 20) and lung cancer (n = 11). In 70 (74%) families the pattern of inheritance was consistent with an autosomal dominant trait. Compared to the preceding generation, a younger age of onset was observed in the offspring of PC patients (median: 57 vs. 69 years), indicating anticipation. Mutation analyses of BRCA2, PALB2, CDKN2a, RNASEL, STK11, NOD2, CHEK2 and PALLD, revealed deleterious causative germline mutations of BRCA2 and PALB2 in 2 of 70 (3%) and 2 of 41 (4.9%) German FPC families, respectively. Prospective PC screening with EUS, MRI and MRCP detected precancerous lesions (IPMN, multifocal PanIN2/3) or carcinoma in 5.5% (4 of 72) to 12.5% (9 of 72) of individuals at risk, depending on histological verification. Appropriate inclusion of families at high risk for PC in registries, such as FaPaCa, provides a unique and excellent tool to gain clinical and genetic knowledge of FPC. Focused research projects can be conducted most efficiently, when data of different FPC registries are combined.

Schneider R; Slater EP; Sina M; Habbe N; Fendrich V; Matthäi E; Langer P; Bartsch DK

2011-06-01

102

German national case collection for familial pancreatic cancer (FaPaCa): ten years experience.  

Science.gov (United States)

Familial pancreatic cancer (FPC) is a rare hereditary tumor syndrome. The 10-years experience of the national case collection for familial pancreatic cancer of Germany (FaPaCa) is reported. Since 1999 FaPaCa has collected families with at least two first-degree relatives with confirmed pancreatic cancer (PC), who did not fulfill the criteria of other hereditary tumor syndromes. Histopathological verification of tumor diagnoses, and genetic counseling were prerequisites for enrollment of families in FaPaCa. 94 of 452 evaluated families fulfilled the criteria for partaking in FaPaCa. PC represented the sole tumor entity in 38 (40%) families. In 56 families additional tumor types occurred, including breast cancer (n = 28), colon cancer (n = 20) and lung cancer (n = 11). In 70 (74%) families the pattern of inheritance was consistent with an autosomal dominant trait. Compared to the preceding generation, a younger age of onset was observed in the offspring of PC patients (median: 57 vs. 69 years), indicating anticipation. Mutation analyses of BRCA2, PALB2, CDKN2a, RNASEL, STK11, NOD2, CHEK2 and PALLD, revealed deleterious causative germline mutations of BRCA2 and PALB2 in 2 of 70 (3%) and 2 of 41 (4.9%) German FPC families, respectively. Prospective PC screening with EUS, MRI and MRCP detected precancerous lesions (IPMN, multifocal PanIN2/3) or carcinoma in 5.5% (4 of 72) to 12.5% (9 of 72) of individuals at risk, depending on histological verification. Appropriate inclusion of families at high risk for PC in registries, such as FaPaCa, provides a unique and excellent tool to gain clinical and genetic knowledge of FPC. Focused research projects can be conducted most efficiently, when data of different FPC registries are combined. PMID:21207249

Schneider, Ralph; Slater, Emily P; Sina, Mercede; Habbe, Nils; Fendrich, Volker; Matthäi, Elvira; Langer, Peter; Bartsch, Detlef K

2011-06-01

103

Mercury Studies around the Mediterranean Sea Basin: Ten years of Measurements and Modeling results  

Directory of Open Access Journals (Sweden)

Full Text Available Only a few years ago the presence of Reactive Gaseous Mercury (RGM) was believed to be almost exclusively the result of anthropogenic emissions and that sustained high RGM concentrations in the MBL were not considered likely. During the past ten years, an in-depth investigation was carried out in the Marine Boundary Layer (MBL) of the Mediterranean Sea to quantify and possibly explain spatial and temporal patterns of Hg-species concentrations. This paper provides an overview of modeling results and atmospheric measurements performed during several cruise campaigns performed aboard the Research Vessel (RV) URANIA of the CNR over the Mediterranean sea basin. RGM concentrations have been modelled using a photochemical box model of the MBL and compared to measured data obtained during the research cruises. The comparison results supports the hypothesis that there are daytime mercury oxidation reactions occurring which have not yet been identified. Major findings of key studies carried out during ten years of ship-borne activities have been highlighted.

Sprovieri F.; Hedgecock I.M.; Pirrone N.

2013-01-01

104

Medical School Attrition-Beyond the Statistics A Ten Year Retrospective Study  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background Medical school attrition is important - securing a place in medical school is difficult and a high attrition rate can affect the academic reputation of a medical school and staff morale. More important, however, are the personal consequences of dropout for the student. The aims of our study were to examine factors associated with attrition over a ten-year period (2001–2011) and to study the personal effects of dropout on individual students. Methods The study included quantitative analysis of completed cohorts and qualitative analysis of ten-year data. Data were collected from individual student files, examination and admission records, exit interviews and staff interviews. Statistical analysis was carried out on five successive completed cohorts. Qualitative data from student files was transcribed and independently analysed by three authors. Data was coded and categorized and key themes were identified. Results Overall attrition rate was 5.7% (45/779) in 6 completed cohorts when students who transferred to other medical courses were excluded. Students from Kuwait and United Arab Emirates had the highest dropout rate (RR?=?5.70, 95% Confidence Intervals 2.65 to 12.27;p? Absenteeism was documented in 30% of students, academic difficulty in 55.7%, social isolation in 20%, and psychological morbidity in 40% (higher than other studies). Qualitative analysis revealed recurrent themes of isolation, failure, and despair. Student Welfare services were only accessed by one-third of dropout students. Conclusions While dropout is often multifactorial, certain red flag signals may alert us to risk of dropout including non-EU origin, academic struggling, absenteeism, social isolation, depression and leave of absence. Psychological morbidity amongst dropout students is high and Student Welfare services should be actively promoted. Absenteeism should prompt early intervention. Behind every dropout statistic lies a personal story. All medical schools have a duty of care to support students who leave the medical programme.

Maher Bridget M; Hynes Helen; Sweeney Catherine; Khashan Ali S; O’Rourke Margaret; Doran Kieran; Harris Anne; Flynn Siun

2013-01-01

105

Ipsilateral combination of Galeazzi and Monteggia fractures in a ten-year-old patient: a case report.  

UK PubMed Central (United Kingdom)

Galeazzi fractures represent approximately 3 to 6 percent of forearm fractures, whereas Monteggia fractures represent 1 to 2 percent. The combination of these injuries in the same extremity is an exceedingly rare occurrence. We report a case of ipsilateral combination of Galeazzi and Monteggia fractures in a ten-year-old patient. The patient was treated with closed reduction and internal fixation with Kirschner pins. The distal radioulnar and radiocapitellar joint relationships were restored and the fractures healed. The patient proceeded to obtain a satisfactory functional result three years later. Internal fixation is a safe method for such complex forearm fractures in older children and allows post-operative rehabilitation with the advantage of early mobilization.

Akalin Y; Akinci O; Kayali C

2010-09-01

106

4. A ten-year study of pharmacotherapeutic approach to tuberculosis at a tertiary hospital in south west Nigeria  

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Full Text Available A retrospective study of a ten-year pharmacotherapeutic approach in the management of tuberculosis (TB) at the University College Hospital Ibadan was made. The primary purpose was to evaluate the treatments outcome of the therapeutic regimen prescribed during a period of ten years. A total number of 975 case notes from medical records of outpatients and inpatients with tuberculosis were thoroughly studied. This represented 492 (50.5%) males and 483 (49.5%) females. Nine hundred and three (903) (92.6%) were new cases, 32 (3.4%) were relapse cases, 3 (0.3%) were failure cases from previous TB treatment, 26 (2.7%) were returned cases after default treatment and 10 (1.0%) cases were transferred. The anti TB regimen reviewed showed the prescribed drugs to be 2RHZE/6RH 661 (67.8%), 2RHZE/6EH 182 (18.7%), 2SHRZE/6RHZE 26 (2.7%), 2SRHZE/RHZE/6RH 32 (3.3%) and others 47 (4.8%), where R= Rifampicin (RMP), H= Isoniazid (INH), Z= Pyrazinamide (PZA), E= Ethambutol (EMB) and S= Streptomycin (STM). The major concomitant drugs prescribed were multivitamins 364 (37.3%) analgesics 340 (34.9%), other antibiotics 229 (23.5%), expectorants 197 (20.2%), antimalarials 174 (17.8%), antihistamines 147 (15.1%), bronchodilators 77 (7.9%), antacids 49 (5.0%), and pyridoxine 333 (34.2%). Side effects documented were visual impairment 43 (13.2%), pedal oedema 14 (4.3%), peripheral neuropathy 20 (6.2%), insomnia 40 (12.3%), gastrointestinal side effects 88 (27.1%), headache 13 (4.0%), rashes 10 (3.1%), liver dysfunction 6 (1.8%), arthralgia 28 (8.6%), irrational behaviour 8 (2.5%), pruritus 15 (4.6%), palpitations 3 (0.9%), anaemia 7 (2.19%), hearing impairment 2 (0.6%) and others 24 (7.5%). The findings revealed that consideration should be given to co-existing disease conditions and current medication needs of TB patients.

M.K. Omole; O. Ebitigha

2011-01-01

107

Hemicrania continua: a report of ten new cases Hemicrania continua: relato de dez novos casos  

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Full Text Available Hemicrania continua (HC) is an uncommon primary headache first described as a syndrome in 1984. Being quite unusual, its clinical characterization still demands better description. The aim of this study is to present the main clinical characteristics of 10 patients with the diagnosis of HC seen in a tertiary center, critically discussing their main features. All subjects had strictly unilateral headache without side shift and absolute response to indomethacin. Seven patients (70%) presented autonomic features during pain exacerbations. Four (40%) had migrainous symptoms during the exacerbations and one presented partial relief with dihydroergotamine. One patient had pain excruciatingly severe during the exacerbations. Although the cardinal features of HC - continuous, unilateral, indomethacin responsive, remain strongly reliable, a refinement on the clinical characterization is needful and desired.Hemicrania continua (HC) é uma cefaléia primária relativamente incomum primeiramente descrita enquanto sindrome em 1984. Por ser relativamente rara, sua apresentação clínica ainda carece de melhor descrição. O objetivo do presente estudo é apresentar e criticamente discutir as principais características clínicas de 10 pacientes com HC consecutivamente vistos em um centro de atendimento especializado. Todos os pacientes apresentavam cefaléia estritamente unilateral, sem alternância de lado e com absoluta resposta a indometacina. Sete pacientes (70%) apresentavam sinais autonômicos durante a exacerbação da dor. Quatro (40%) apresentavam sintomas migranosos durante as exacerbações e um apresentava alívio parcial com diidroergotamina. Um paciente apresentava exacerbações excruciantemente severas. Embora as principais características da HC - dor continua, unilateral, responsiva à indometacina - permaneçam extremamente associados à sindrome, um refinamento na caracterização clínica é necessário.

Marcelo E. Bigal; Stewart J Tepper; Fred D. Sheftell; Alan M. Rapoport

2002-01-01

108

Ten-year fatal and non-fatal myocardial infarction incidence in elderly populations in Spain: the EPICARDIAN cohort study  

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Full Text Available Abstract Background In Spain, more than 85% of coronary heart disease deaths occur in adults older than 65 years. However, coronary heart disease incidence and mortality in the Spanish elderly have been poorly described. The aim of this study is to estimate the ten-year incidence and mortality rates of myocardial infarction in a population-based large cohort of Spanish elders. Methods A population-based cohort of 3729 people older than 64 years old, free of previous myocardial infarction, was established in 1995 in three geographical areas of Spain. Any case of fatal and non-fatal myocardial infarction was investigated until December 2004 using the "cold pursuit method", previously used and validated by the the WHO-MONICA project. Results Men showed a significantly (p Conclusion Incidence of fatal and non-fatal myocardial infarction is high in the Spanish elderly population. Men show higher rates than women, but gender differences diminish with age.

Gabriel Rafael; Alonso Margarita; Reviriego Blanca; Muñiz Javier; Vega Saturio; López Isidro; Novella Blanca; Suárez Carmen; Rodríguez-Salvanés Francisco

2009-01-01

109

[Entomological investigations conducted around ten cases of yellow fever in 2009 in the Denguele sanitary region, Cote-d'Ivoire].  

UK PubMed Central (United Kingdom)

In November 2009, ten suspicious cases of yellow fever, including six deaths, were notified in the region of Denguélé, in the northwest of Côte-d'Ivoire. In order to evaluate the extent of yellow fever virus circulation and the risk for local people, a mission of entomological investigation was carried out by the Ministry of Health and Public Hygiene of Côte-d'Ivoire. Entomological investigations were conducted in the villages of confirmed cases (Banakoro and Tron-Touba) and the centers of consultation and hospitalization of cases during illness. Breteau index and recipient index were quasi nil. Aedes aegypti was absent among the captured mosquitoes. On the other hand, Aedes luteocephalus and Aedes opok were present at Banakoro and Tron-Touba with respective average biting rates of 0.8 and 0.6 bite/man/twilight. This situation of epidemic in the northwest of Côte-d'Ivoire could be explained by the deterioration of Denguélé region's health system which is a consequence of the war started in the country in 2002 and which has lowered the immunity of the population.

Konan YL; Fofana D; Coulibaly ZI; Diallo A; Koné AB; Doannio JM; Ekra KD; Odéhouri-Koudou P

2011-10-01

110

Native American Case Studies  

Science.gov (United States)

The Native American Case Studies collection includes more than 80 original, research-based teaching cases focusing on contemporary issues in Indian Country. Teaching notes accompany each case. These can be downloaded and used at no cost. Additional website resources include information on teaching with cases and assessment. Guidelines for submitting cases are also available.

College, The E.; College, Northwest I.; College, Salish K.; College, Grays H.

111

Medical school attrition-beyond the statistics a ten year retrospective study.  

UK PubMed Central (United Kingdom)

BACKGROUND: Medical school attrition is important--securing a place in medical school is difficult and a high attrition rate can affect the academic reputation of a medical school and staff morale. More important, however, are the personal consequences of dropout for the student. The aims of our study were to examine factors associated with attrition over a ten-year period (2001-2011) and to study the personal effects of dropout on individual students. METHODS: The study included quantitative analysis of completed cohorts and qualitative analysis of ten-year data. Data were collected from individual student files, examination and admission records, exit interviews and staff interviews. Statistical analysis was carried out on five successive completed cohorts. Qualitative data from student files was transcribed and independently analysed by three authors. Data was coded and categorized and key themes were identified. RESULTS: Overall attrition rate was 5.7% (45/779) in 6 completed cohorts when students who transferred to other medical courses were excluded. Students from Kuwait and United Arab Emirates had the highest dropout rate (RR = 5.70, 95% Confidence Intervals 2.65 to 12.27;p < 0.0001) compared to Irish and EU students combined. North American students had a higher dropout rate than Irish and EU students; RR = 2.68 (1.09 to 6.58;p = 0.027) but this was not significant when transfers were excluded (RR = 1.32(0.38, 4.62);p = 0.75). Male students were more likely to dropout than females (RR 1.70, .93 to 3.11) but this was not significant (p = 0.079).Absenteeism was documented in 30% of students, academic difficulty in 55.7%, social isolation in 20%, and psychological morbidity in 40% (higher than other studies). Qualitative analysis revealed recurrent themes of isolation, failure, and despair. Student Welfare services were only accessed by one-third of dropout students. CONCLUSIONS: While dropout is often multifactorial, certain red flag signals may alert us to risk of dropout including non-EU origin, academic struggling, absenteeism, social isolation, depression and leave of absence. Psychological morbidity amongst dropout students is high and Student Welfare services should be actively promoted. Absenteeism should prompt early intervention. Behind every dropout statistic lies a personal story. All medical schools have a duty of care to support students who leave the medical programme.

Maher BM; Hynes H; Sweeney C; Khashan AS; O'Rourke M; Doran K; Harris A; Flynn SO

2013-01-01

112

Share Food Case Study.  

Science.gov (United States)

The Share Food Case Study was prepared for use in the 2007 Malcolm Baldrige National Quality Award Examiner Preparation Course. The Share Food Case Study describes a fictitious nonprofit organization. There is no connection between the fictitious Share Fo...

2007-01-01

113

A ten-year prospective study of aggression in a special secure unit for dangerous patients.  

UK PubMed Central (United Kingdom)

In a 10-year prospective study inpatient aggression was investigated in a Norwegian special secure unit covering a well-defined catchment area with a population of 240,000. The seven bed special secure unit receives dangerous, psychotic patients for long-term treatment. Only 19 patients were treated during the ten-year study lasting from 1 April 1987 to 1 April 1997. Incidents of aggressive behavior were recorded on the Report Form for Aggressive Episodes by the nursing staff. The study aimed to identify, classify and measure the occurrence of aggressive behavior, as well as the relative frequency of events preceding such behavior. A total of 2021 incidents of aggressive behavior were recorded. Seventy-five per cent of the aggressive acts were verbal or physical threats, while the remaining 25% were physical assaults directed at other persons. Four patients accounted for about 80% of the aggressive encounters. Nursing staff were victims in about 90% of the incidents. Serious physical injury was extremely rare. Situations pertaining to limit-setting and problems of communication accounted for approximately 90% of the precipitants of aggressive behavior. There were no sex differences regarding the occurrence of aggressive behavior.

Bjørkly S

1999-03-01

114

Teaching with Case Studies.  

Science.gov (United States)

Guidelines are provided in this handbook for secondary level teachers on how to develop and use case studies in their social studies and economics classes. Among the contents are the following: (1) a description of the case study method and its educational goals; (2) the act of case discussion; (3) questioning techniques to use and sample…

Tedesco, Paul H.

115

Case Study Research  

Science.gov (United States)

|Case study research aims to explore and depict a setting with a view to advancing understanding. This note explores the dimensions of case study research in higher education, with special reference to geographical fieldwork. It explores Stake's three categories of case study research: intrinsic, instrumental and collective. It provides guidelines…

Cousin, Glynis

2005-01-01

116

Sífilis ocular: Presentación de diez casos y revisión de la literatura Ocular syphilis: Ten new cases and review of the literature  

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Full Text Available Introducción: Las manifestaciones oculares de los pacientes con sífilis pueden comprometer cualquiera de las estructuras del ojo. Objetivos: Describir diez nuevos casos de sífilis con compromiso ocular y realizar una breve discusión de su manejo y tratamiento. Pacientes y Métodos: Se estudiaron, de forma retrospectiva, diez casos en un período de 13 años. Se evaluaron factores demográficos, exámenes oftalmológico y de laboratorio. Resultados: De los diez casos, 7 eran hombres y 3 mujeres. El promedio de edad fue de 39,7 años. Las presentaciones fueron: panuveítis (n: 6), neuritis óptica (n: 3), vasculitis retinal (n: 1) y pupila de Argyll-Robertson (n: 1). Se obtuvo VDRL (+) en líquido cefalorraquídeo en 6 pacientes y serología para VIH (+) en 3 pacientes. Conclusiones: La sífilis puede producir variadas manifestaciones oftalmológicas. No en todos los casos el VDRL resultó positivo en el LCR. El tratamiento anti-treponémico produce una rápida y efectiva respuesta en los pacientes afectados.Introduction: Ocular manifestations in patients with syphilis may involve almost any of the structures of the eye. Objectives: To describe ten new cases of syphilis with eye involvement and to briefly discuss the management and therapy of such condition. Material and Methods: Ten cases were retrospectively studied over 13 years. Demographic factors, ophthalmologic examination, and laboratory tests were assessed. Results: Seven of the 10 cases were male and 3 were female. The mean age of patients was 39,7 years. Disease presentation included: panuveitis (6 patients), optic neuritis (3), retinal vasculitis (1) and Argyll-Robertson pupil (1). Cerebrospinal fluid VDRL test was positive in 6 patients and 3 patients were HIV (+). Conclusions: Syphilis is able to display diverse ophthalmologic manifestations. Not in all the cases the CSF-VDRL test was positive. Antitreponemal therapy generates a fast and effective response in the affected patients.

Pablo Romero C; Cristhían Urzúa S; Patricia Gallardo V; Juan Verdaguer T; Marta Lechuga C; Helio Hernández N; Felipe Sanhueza Z; Matías Andaur L; Eugenio Donaire V

2010-01-01

117

Sífilis ocular: Presentación de diez casos y revisión de la literatura/ Ocular syphilis: Ten new cases and review of the literature  

Scientific Electronic Library Online (English)

Full Text Available Abstract in spanish Introducción: Las manifestaciones oculares de los pacientes con sífilis pueden comprometer cualquiera de las estructuras del ojo. Objetivos: Describir diez nuevos casos de sífilis con compromiso ocular y realizar una breve discusión de su manejo y tratamiento. Pacientes y Métodos: Se estudiaron, de forma retrospectiva, diez casos en un período de 13 años. Se evaluaron factores demográficos, exámenes oftalmológico y de laboratorio. Resultados: De los diez casos, (more) 7 eran hombres y 3 mujeres. El promedio de edad fue de 39,7 años. Las presentaciones fueron: panuveítis (n: 6), neuritis óptica (n: 3), vasculitis retinal (n: 1) y pupila de Argyll-Robertson (n: 1). Se obtuvo VDRL (+) en líquido cefalorraquídeo en 6 pacientes y serología para VIH (+) en 3 pacientes. Conclusiones: La sífilis puede producir variadas manifestaciones oftalmológicas. No en todos los casos el VDRL resultó positivo en el LCR. El tratamiento anti-treponémico produce una rápida y efectiva respuesta en los pacientes afectados. Abstract in english Introduction: Ocular manifestations in patients with syphilis may involve almost any of the structures of the eye. Objectives: To describe ten new cases of syphilis with eye involvement and to briefly discuss the management and therapy of such condition. Material and Methods: Ten cases were retrospectively studied over 13 years. Demographic factors, ophthalmologic examination, and laboratory tests were assessed. Results: Seven of the 10 cases were male and 3 were female. (more) The mean age of patients was 39,7 years. Disease presentation included: panuveitis (6 patients), optic neuritis (3), retinal vasculitis (1) and Argyll-Robertson pupil (1). Cerebrospinal fluid VDRL test was positive in 6 patients and 3 patients were HIV (+). Conclusions: Syphilis is able to display diverse ophthalmologic manifestations. Not in all the cases the CSF-VDRL test was positive. Antitreponemal therapy generates a fast and effective response in the affected patients.

Romero C, Pablo; Urzúa S, Cristhían; Gallardo V, Patricia; Verdaguer T, Juan; Lechuga C, Marta; Hernández N, Helio; Sanhueza Z, Felipe; Andaur L, Matías; Donaire V, Eugenio

2010-12-01

118

Project Management Case Studies  

CERN Document Server

The revised edition of the single-best source of project management case studies Compiled by Harold Kerzner, the leading authority on project management, Project Management Case Studies, Third Edition presents the most comprehensive collection of project management case studies available today. Featuring more than 100 case studies, this essential book illustrates both successful implementation of project management by actual companies as well as the pitfalls to avoid in a variety of real-world situations. This new edition: Contains case studies illustrating successful and poor implementation

Kerzner, Harold

2010-01-01

119

Do Karst Rivers “deserve” their own biotic index? A ten years study on macrozoobenthos in Croatia  

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Full Text Available In this study we present the results of a ten year survey of the aquatic macroinvertebrate fauna along four karst rivers: Jadro, Žrnovnica, Grab and Ruda, all of them situated in the Middle Dalmatia region of Croatia, in an attempt to construct the Iliric Biotic Index, which will be more applicable for the water quality analysis than the most frequently applied biotic index in Croatia, the Italian Modification of Extended Biotic Index. The rivers geologically belong to the Dinaric karst, unique geological phenomena in Europe. Benthic macroinvertebrates were collected along each river at 15 sites by standard methods of sampling along with several physicochemical parameters, including: temperature, dissolved oxygen, carbon dioxide, alkalinity, hardness and pH. Univariate and multivariate techniques revealed differences in the macroinvertebrate community structure as well as in physicochemical parameters between the Karst rivers and continental rivers. Based on those differences, the Iliric Biotic Index was proposed as the standard of karst river water quality in Croatia in accordance with the EU Water Framework Directive. Differences between the Iliric Biotic Index and the most commonly used biotic indices in the European Community and the USA (The Biological Monitoring Working Party (B.M.W.P.) scores, i.e. Extended Biotic Index, Indice Biotique, Family Biotic Index) suggest that karst rivers need a new biotic index.

Ra?a Biljana; Puljas Sanja

2010-01-01

120

Tumor del cuerpo carotídeo: A propósito de 10 casos tratados/ Carotid body tumors: Report of ten cases  

Scientific Electronic Library Online (English)

Full Text Available Abstract in english Background: Carotid body tumors arise from a cellular conglomerate located at the carotid bifurcation. Progressive enlargement can involve the arterial wall and neighbor cranial nerves. Aim: To report a series of 10 patients treated of carotid body tumors and review national experience. Patients and methods: Between 1984 and 2006, we operated 8 women and 2 men, aged 19 to 75 years, with this type of tumor. Results: The most common cause for consultation was a cervical mas (more) s in 90%, with a mean evolution lapse of 13.2 months (range 3 to 126). In all cases, diagnosis was confirmed with angiographic imaging and histopathology. Ten tumors were surgically removed with no complications. Eighty percent of tumors were in stage II according to Shamblin classification. During long term follow up all patients have remained asymptomatic. Only 31 carotid body tumors have been reported in Chilean medical literature during a 43 year period. Conclusions: Paragangliomas of the carotid body can be diagnosed in clinical grounds, requiring vascular imaging. These infrequent lesions are generally benign, early surgical removal by surgeons with vascular expertise avoids neurological and or vascular complications

Soto G, Sebastián; Valdés E, Francisco; Krámer Sen, Albrecht; Mariné M, Leopoldo; Bergoeing R, Michel; Mertens M, Renato; Solar G, Antonieta; Walton D, Annerleim; Vergara G, Jeannette

2007-11-01

 
 
 
 
121

Breath-hold two-dimensional MR angiography of coronary arteries. Comparison with conventional coronary angiography in ten cases  

International Nuclear Information System (INIS)

[en] Purpose: To assess the diagnostic value of two-dimensional coronary magnetic resonance (MR) angiography in patients evaluated for ischemic heart disease. Materials and methods: Ten patients who underwent selective cardiac catheterization with coronary MR angiography were evaluated with two-dimensional coronary MR angiography. Coronary MR angiography was performed with breath-hold fat-suppressed ECG-gated Turbo-FLASH with K-space segmentation using a 1.5 T imager. Results: The left main coronary artery, proximal left anterior descending artery, circumflex artery and right coronary artery were demonstrated in all cases. Continuous segments (mean) of left anterior descending, circumflex and right coronary arteries visualized on MRA were 6.72 +- 3.16 cm, 3.67 +- 4.81 cm and 7.93 +- 3.12 cm respectively. The overall sensitivity for detection of hemodynamically significant coronary artery lesion (?50%) was 62.5% respectively. Conclusion: Breath-hold two-dimensional coronary MR angiography was useful in showing relatively long segments of the main coronary arteries and also has potential in depicting hemodynamically significant coronary artery lesions

1997-01-01

122

[Reconstruction of the mouth floor using a musculo-mucosal buccinator flap supplied by facial vessels. Report of ten cases].  

Science.gov (United States)

The buccinator muscle is a wide, flat quadrangular muscle. Its medial surface is covered by the oral mucosa. It receives its arterial blood supply from two main arteries: the facial and buccal arteries. A musculo-mucosal flap can be raised on the facial artery with or without the facial vein. In the case of absence of the facial vein, venous drainage is possible into the peri-arterial loose areolar tissue. A nasolabial skin incision facilitates facial artery identification and simplifies flap dissection in the loose areolar plane, superficial to the facial artery. The mean dimensions of the flap are 3.5 cm in width and 7 cm in length. The flap extends from the superior buccal sulcus to the inferior alveolar ridge. Its rotation enables reconstruction of the anterior and lateral floor of the mouth. The donor site is closed in two layers. The authors present a series of ten patients reconstructed with this flap after excision of a squamous cell carcinoma of the floor of the mouth. The results are excellent with perfect tongue function and no esthetic sequelae. The facial artery should be preserved during neck dissection, and the ipsilateral mandibular molar teeth must be extracted. Its simplicity and reliability makes this flap a useful alternative in floor of mouth reconstruction. PMID:9768068

Abou Chebel, N; Beziat, J L; Torossian, J M

1998-06-01

123

Tumor del cuerpo carotídeo: A propósito de 10 casos tratados Carotid body tumors: Report of ten cases  

Directory of Open Access Journals (Sweden)

Full Text Available Background: Carotid body tumors arise from a cellular conglomerate located at the carotid bifurcation. Progressive enlargement can involve the arterial wall and neighbor cranial nerves. Aim: To report a series of 10 patients treated of carotid body tumors and review national experience. Patients and methods: Between 1984 and 2006, we operated 8 women and 2 men, aged 19 to 75 years, with this type of tumor. Results: The most common cause for consultation was a cervical mass in 90%, with a mean evolution lapse of 13.2 months (range 3 to 126). In all cases, diagnosis was confirmed with angiographic imaging and histopathology. Ten tumors were surgically removed with no complications. Eighty percent of tumors were in stage II according to Shamblin classification. During long term follow up all patients have remained asymptomatic. Only 31 carotid body tumors have been reported in Chilean medical literature during a 43 year period. Conclusions: Paragangliomas of the carotid body can be diagnosed in clinical grounds, requiring vascular imaging. These infrequent lesions are generally benign, early surgical removal by surgeons with vascular expertise avoids neurological and or vascular complications

Sebastián Soto G; Francisco Valdés E; Albrecht Krámer Sen; Leopoldo Mariné M; Michel Bergoeing R; Renato Mertens M; Antonieta Solar G; Annerleim Walton D; Jeannette Vergara G

2007-01-01

124

Granuloma central de células gigantes: presentación de diez casos/ Central giant cell granuloma: presentation of ten cases  

Scientific Electronic Library Online (English)

Full Text Available Abstract in spanish Fundamento: el granuloma central de células gigantes (GCCG) es una lesión que ocupa el 7 % de los tumores benignos que se encuentra exclusivamente en los maxilares. Se presenta con más frecuencia en mujeres que en hombres y predomina en la segunda y tercera década de la vida. Las características radiográficas del GCCG son variables y pueden ser confundidas con otras lesiones de los maxilares. El GCCG puede tener un comportamiento agresivo lo que permite establecer e (more) l tratamiento de elección, incluyendo la enucleación, el curetaje y la resección en bloque de la lesión. Caso clínico: se presentaron diez casos de pacientes diagnosticados con GCCG. El 80 % de los casos se localizaron en la mandíbula con las siguientes características clínicas: asimetría facial, desplazamiento dental, reabsorción radicular, alteración de la oclusión y trastorno nervioso. Conclusiones: en cuatro sujetos se realizó resección en bloque con placa de reconstrucción, mientras que en los otros seis pacientes se llevó a cabo enucleación y curetaje. En el 100 % de los casos se efectuó un abordaje intraoral y no se presentaron complicaciones graves. El seguimiento clínico y radiográfico evidenció recidiva en uno de los pacientes, razón por la cual se precedió a realizar resección en bloque con placa de reconstrucción. Abstract in english Background: central giant cell granuloma (CGCG) is a lesion that occupies 7 % of benign tumors found exclusively in the jaws. It occurs more frequently in women than in men and predominates in the second and third decades of life. Radiographic features of CGCG are changeable, and may be confused with other jaws' lesions. The CGCG may have aggressive behavior which allows setting the treatment of choice, including enucleation, curettage and resection of the lesion. Clinica (more) l case: ten cases of patients diagnosed with CGCG were presented. The 80 % of the cases were located in the jaw with the following clinical features: facial asymmetry, dental displacement, root resorption, altered occlusion and nerve disorder. Conclusions: in four patients resection in block was performed with reconstruction plate, while in six other patients enucleation and curettage was carried out. In the 100 % of the cases an intraoral approach was made without severe complications. There was clinical and radiographic evidence of recidivation in one of the patients, a resection with reconstruction plate was made.

Duque Serna, Francisco Levi; Franco, Lina María; Ardila Medina, Carlos Martín

2012-10-01

125

[Analgesic efficacy of TENS therapy in patients with gonarthrosis. A prospective, randomised, placebo-controlled, double-blind study].  

UK PubMed Central (United Kingdom)

BACKGROUND: The goal of the study was to substantiate the influence of TENS on pain development and medication needs of patients with proven gonarthrosis and chronic pain. The study included a 3-week stimulation period and 2-week observation period after the end of stimulation. MATERIALS AND METHODS: Patients (at least 20 per group) were assigned to either an active treatment group or placebo group in a randomised, double-blind, placebo-controlled trial. For the active treatment group the TENS therapy device with HAN stimulation (alternating phase of stimulation) was used (TENStem eco).Total length of time: 30 min at least two times a day. The length of therapy was 3 weeks (therapy), followed by an observation period of 2 weeks (follow-up). The total length of the study was 5 weeks, whereby at the beginning and at the end of weeks 1, 3 and 5 the SF-36, WOMAC score and Lysholm score were documented; the pain score was documented daily. RESULTS: There are no significant demographic differences between the groups. In the active treatment group there was clear relief in pain intensity in the morning, midday and evening over the 3-week period of therapy. The Lysholm score in the active treatment group was 53.4 at the beginning, 90 after 1 week, 94.5 after the third week and 91 by the fifth week (significant difference). There were no side effects. CONCLUSION: TENS therapy with HAN stimulation resulted in pain relief in patients with gonarthrosis during the therapy period with TENS, but the pain relief did not last beyond the end of the TENS therapy. There was an improvement in the Lysholm score and the WOMAC score during the therapy. This improvement remained over the following 2-week period of observation without further TENS therapy. TENS therapy is a simple and effective method to treat gonarthrosis with very few side effects.

Gschiel B; Kager H; Pipam W; Weichart K; Likar R

2010-09-01

126

Perinatal Mortality And Pregnancy Wastage In Ten Punjab Villages During 1991-1996 - A Population Based Study  

Directory of Open Access Journals (Sweden)

Full Text Available Research question: What is the extent of perinatal mortality and pregnancy wastage in rural Punjab and what are risk factors for the same. Objective: To quantify the perinatal; wastage and risk factors including the prevalence of these factors to determine the loss attributable to these factors in ten Punjab villages during the period 1991-1996. Study Design: Case control. Sample Size: 2519 pregnant women with Known outcome of pregnancy. Study Variables: Cause, timing and factors affecting perinatal mortality and pregnancy wastage (viz Wt.<40kg; Ht, <152cm,BMI, <20 illiteracy, birth to conception interval <100wks, Prematurity (Gestation <37 wks). Registered in IIIrd trimester, Registered in IInd Trimester, Home delivery). Outcome variables: Contribution of these factors in perinatal loss and pregnancy wastage. Analysis; Percentages, Odds ratio, confidence interval and population attributable risk%. Results: The perinatal mortality rate was 34.57/1000 and pregnancy wastage was 7.23%. Prematurity was the leading cause of perinatal loss. 31.25% of perinatal deaths took place within 24 hours and 87.5% within 96 hours. In case of perinatal mortality the odds ration were significant (p<0.05) for the following risk factors: weight, height, body mass index, illiteracy, birth to conception interval <1000 weeks, prematurity, registration of pregnancy in IInd trimester, registration of pregnancy in IIIrd trimester, home delivery. In case of pregnancy wastage the odds ratio were significant for the following risk factors: weight, height, body mass index, illiteracy, birth to conception interval <100weeks, prematurity, past history of abortion and low socio-economic status.

Sachar R.K; Soni R.K; Singh W.P; Dhot Ramnik; Gill P.J.S; Arora Sona; Singh Hari; Dhiman B

1998-01-01

127

Ten-year epidemiological study of chemical burns in Jinshan, Shanghai, PR China.  

UK PubMed Central (United Kingdom)

BACKGROUND: The epidemiological pattern of chemical burns varies widely in different areas of the world. To analyse effective preventive approaches, an insight into the pattern of injury is desirable. However, our data are only limited to Shanghai area, China. METHODS: A 10-year retrospective review includes all patients with chemical burns admitted to the Department of Burn and Plastic Surgery from January 2001 to December 2010; those who were admitted to the ophthalmologic department or other departments were excluded. The data collected included age, gender, injury pattern, patient workplaces, aetiological agents, incidence by month and year, burn size, burn depth and site, time for immediate irrigation, length of hospital stay and outcome. RESULTS: A total of 615 patients admitted to our department for in-hospital treatment of chemical burn injury were included in the study. The mean age was 32.1±12.3 years with a range of 2-66 years. A total of 562 cases (91.4%) were male and 53 cases (8.6%) female. The mean total burn surface area (TBSA) was 30.3±24.7% with a mean full-thickness burn area of 17.5±23.8%. Most chemical burns took place in summer and fall. The majority of chemical burns were work related (93.0%); among them accidents that happened in private factories were predominant (70.8%). Although caustic soda was the leading cause of all chemical burns (15.8%), acid burn was the most common (45.2%). The extremities were the most frequent areas of injuries, followed by head and neck. Most cases had none (30.4%) or insufficient (61.1%) immediate irrigation after injury. In all patients, 47 cases had inhalation injuries, 94 cases accompanying ophthalmologic burns, 51 cases accompanying other associated injuries and 67 cases chemical toxicity. A total of 212 cases (34.5%) underwent early total or tangential excision and skin or skin flap grafting in the first week after injury. The mean length of hospital stay was 44.1±24.7 days. Sixteen cases died of respiratory failure, sepsis or multiple organ dysfunction syndrome (MODS), giving a mortality rate of 2.6%. CONCLUSION: Safety training, preventive measures and following safety rules and strict regulation are of paramount importance for workers to prevent and reduce chemical burns in chemical enterprises, especially in private factories. Appropriate first-aid training that includes copious spot lavage should be emphasised. Eschar excision as early as possible and skin or skin flap grafting in deep wounds could reduce the possibility of poisoning and disability.

Li W; Wu X; Gao C

2013-04-01

128

The Big Ten Student Suicide Study: A 10-Year Study on Suicides on Midwestern University Campuses.  

Science.gov (United States)

Addresses many of the statistical and epidemiological flaws identified in previous studies of campus student suicides. Analyses, based on longitudinal data covering 261 student suicides, reveal a significantly higher suicide risk for students 25 and over, although the overall student suicide rate is one half of the national rate. (RJM)

Silverman, Morton M.; Meyer, Peter M.; Sloane, Finbarr; Raffel, Madeleine; Pratt, Deborah M.

1997-01-01

129

Impact of endometriosis on quality of life and work productivity: a multicenter study across ten countries.  

UK PubMed Central (United Kingdom)

OBJECTIVE: To assess the impact of endometriosis on health-related quality of life (HRQoL) and work productivity. DESIGN: Multicenter cross-sectional study with prospective recruitment. SETTING: Sixteen clinical centers in ten countries. PATIENT(S): A total of 1,418 premenopausal women, aged 18-45 years, without a previous surgical diagnosis of endometriosis, having laparoscopy to investigate symptoms or to be sterilized. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Diagnostic delay, HRQoL, and work productivity. RESULT(S): There was a delay of 6.7 years, principally in primary care, between onset of symptoms and a surgical diagnosis of endometriosis, which was longer in centers where women received predominantly state-funded health care (8.3 vs. 5.5 years). Delay was positively associated with the number of pelvic symptoms (chronic pelvic pain, dysmenorrhoea, dyspareunia, and heavy periods) and a higher body mass index. Physical HRQoL was significantly reduced in affected women compared with those with similar symptoms and no endometriosis. Each affected woman lost on average 10.8 hours (SD 12.2) of work weekly, mainly owing to reduced effectiveness while working. Loss of work productivity translated into significant costs per woman/week, from US$4 in Nigeria to US$456 in Italy. CONCLUSION(S): Endometriosis impairs HRQoL and work productivity across countries and ethnicities, yet women continue to experience diagnostic delays in primary care. A higher index of suspicion is needed to expedite specialist assessment of symptomatic women. Future research should seek to clarify pain mechanisms in relation to endometriosis severity.

Nnoaham KE; Hummelshoj L; Webster P; d'Hooghe T; de Cicco Nardone F; de Cicco Nardone C; Jenkinson C; Kennedy SH; Zondervan KT

2011-08-01

130

Study on dosimetry systems for a few tens MeV/u ion beams  

Energy Technology Data Exchange (ETDEWEB)

A combined measurement system consisting of a total calorimeter, a Faraday cup and thin film dosimeters have been developed and tested using a simultaneous irradiation apparatus to measure absorbed dose for a few tens MeV/u ion beams of the TIARA AVF cyclotron. (author)

Kojima, Takuji; Sunaga, Hiromi; Takizawa, Haruki; Tachibana, Hiroyuki [Japan Atomic Energy Research Inst., Takasaki, Gunma (Japan). Takasaki Radiation Chemistry Research Establishment

1997-03-01

131

Ten-year clinico-statistical study of oral squamous cell carcinoma  

International Nuclear Information System (INIS)

This clinico-statistical study includes 232 cases of oral squamous cell carcinoma that underwent radical treatment in the Department of Oral and Maxillofacial Surgery, Yokohama City University Hospital, during the decade from 1991 to 2000. Surgery was principally adopted as the first line for treatment in 199 cases, and radiotherapy in 33 cases. The 5-year overall survival rate was 73.4%. The results according to stage were as follows: stage I, 87.5%; Stage II, 77.9%; Stage III, 63.5%; and Stage IV A, 44.7%. The primary sites were classified as follows: upper gingiva, 85.2%; tongue, 73.7%; floor of mouth, 68.9%; lower gingiva, 66.3%; buccal mucosa, 63.9%; and hard palate, 50%. For tongue cancer, the 5-year overall survival rates by stage were: Stage I, 90.8%; Stage II, 82.1%; Stage III, 40.3%; and Stage IV A, 45.7%. Statistical significance was seen between cases of Stages I and II and those of Stages III and IV A stage. For lower gingival cancer, the 5-year overall survival rates by stage were: Stage I, 90.8%; Stage II, 82.1%; Stage III, 40.3%; and Stage IV A, 45.7%. Even in Stage I lower gingival cancers had unfavorable clinical outcomes. Preventive neck dissections were performed on 52 N 0 neck patients, but clinically negative nodes however showed metastasis in 14 patients (26.9%). (author)

2003-01-01

132

Campylobacter antimicrobial resistance in Peru: a ten-year observational study  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background Campylobacter jejuni and Campylobacter coli are food-borne pathogens of great importance and feature prominently in the etiology of developing world enteritis and travellers’ diarrhoea. Increasing antimicrobial resistant Campylobacter prevalence has been described globally, yet data from Peru is limited. Our objective was to describe the prevalence trends of fluoroquinolone and macrolide-resistant C. jejuni and C. coli stool isolates from three regions in Peru over a ten-year period. Methods Surveillance for enteric pathogens was conducted in Lima, Iquitos and Cusco between 2001 and 2010. Campylobacter stool isolates were tested for susceptibilities to ciprofloxacin, azithromycin and erythromycin. Susceptibilities were reviewed for 4652 isolates from Lima ( n?=?3419), Iquitos ( n?=?625) and Cusco ( n?=?608). Results Comparing the study periods of 2001-2005 and 2006-2010, prevalence of ciprofloxacin-resistant C. jejuni isolates rose in the study areas of Lima (73.1% to 89.8%, p?p?C. coli rates also increased in Lima (48.1% to 87.4%, p?p?=?0.005). Small but significant increases in azithromycin-resistant and erythromycin-resistant C. jejuni prevalence were noted in Iquitos (2.2% to 14.9%, p?p?=?0.002), and erythromycin-resistant C. coli rates increased in Lima (0.0% to 5.3%, p?=?0.038). The prevalence of C. jejuni isolates resistant to both ciprofloxacin and azithromycin increased in Iquitos (0.3% to 14.9%, p?C. jejuni isolates resistant to both ciprofloxacin and erythromycin rose in Iquitos (0.0% to 14.9%, p?C. coli prevalence increased in Lima (0.0% to 5.3%, p?=?0.034). Conclusions These results have implications for the empirical management of enterocolitis in Peru. Ongoing surveillance is essential to guide appropriate antimicrobial use in this setting. Local epidemiological studies to explore the relationship between increasing antimicrobial resistance and agricultural or human antibiotic use may be valuable.

Pollett Simon; Rocha Claudio; Zerpa Rito; Patiño Lilian; Valencia Augusto; Camiña Máximo; Guevara José; Lopez Martha; Chuquiray Nancy; Salazar-Lindo Eduardo; Calampa Carlos; Casapia Martín; Meza Rina; Bernal Maruja; Tilley Drake; Gregory Michael; Maves Ryan; Hall Eric; Jones Franca; Arriola C; Rosenbaum Marieke; Perez Juan; Kasper Matthew

2012-01-01

133

Campylobacter antimicrobial resistance in Peru: a ten-year observational study.  

UK PubMed Central (United Kingdom)

BACKGROUND: Campylobacter jejuni and Campylobacter coli are food-borne pathogens of great importance and feature prominently in the etiology of developing world enteritis and travellers' diarrhoea. Increasing antimicrobial resistant Campylobacter prevalence has been described globally, yet data from Peru is limited. Our objective was to describe the prevalence trends of fluoroquinolone and macrolide-resistant C. jejuni and C. coli stool isolates from three regions in Peru over a ten-year period. METHODS: Surveillance for enteric pathogens was conducted in Lima, Iquitos and Cusco between 2001 and 2010. Campylobacter stool isolates were tested for susceptibilities to ciprofloxacin, azithromycin and erythromycin. Susceptibilities were reviewed for 4652 isolates from Lima ( n = 3419), Iquitos ( n = 625) and Cusco ( n = 608). RESULTS: Comparing the study periods of 2001-2005 and 2006-2010, prevalence of ciprofloxacin-resistant C. jejuni isolates rose in the study areas of Lima (73.1% to 89.8%, p < 0.001) and Iquitos (24.1% to 48.9%, p < 0.001). Ciprofloxacin-resistant C. coli rates also increased in Lima (48.1% to 87.4%, p < 0.001) and Cusco (10.0% to 65.9%, p = 0.005). Small but significant increases in azithromycin-resistant and erythromycin-resistant C. jejuni prevalence were noted in Iquitos (2.2% to 14.9%, p < 0.001; 3.2% to 14.9%, p = 0.002), and erythromycin-resistant C. coli rates increased in Lima (0.0% to 5.3%, p = 0.038). The prevalence of C. jejuni isolates resistant to both ciprofloxacin and azithromycin increased in Iquitos (0.3% to 14.9%, p < 0.001) and Lima (0.3% to 1.6%, p = 0.011), and prevalence of C. jejuni isolates resistant to both ciprofloxacin and erythromycin rose in Iquitos (0.0% to 14.9%, p < 0.001). Ciprofloxacin and erythromycin resistant C. coli prevalence increased in Lima (0.0% to 5.3%, p = 0.034). CONCLUSIONS: These results have implications for the empirical management of enterocolitis in Peru. Ongoing surveillance is essential to guide appropriate antimicrobial use in this setting. Local epidemiological studies to explore the relationship between increasing antimicrobial resistance and agricultural or human antibiotic use may be valuable.

Pollett S; Rocha C; Zerpa R; Patiño L; Valencia A; Camiña M; Guevara J; Lopez M; Chuquiray N; Salazar-Lindo E; Calampa C; Casapia M; Meza R; Bernal M; Tilley D; Gregory M; Maves R; Hall E; Jones F; Arriola CS; Rosenbaum M; Perez J; Kasper M

2012-01-01

134

Primary Embryonal Lung Carcinoma and Testicular Seminoma in the Same Patient Ten-Years Later: Case-Report and Literature Review  

Directory of Open Access Journals (Sweden)

Full Text Available Primary germ cell tumors of lung are extremely rare. The prognosis is usually poor, with various symptoms seriously affecting quality of life. In this paper we describe the unique case of a patient affected by an embryonal carcinoma of lung and a testicular seminoma after ten years. We also report literature about pulmonary extragonadal germ cell tumors.

Pasquale Rescigno; Giuseppe Di Lorenzo; Lucia Raimondo; Carmine D’Aniello; Elide Matano; Vincenzo Damiano; Lucia Nappi; Livio Puglia; Antonella Petremolo; Piera Federico; Giovannella Palmieri

2012-01-01

135

Tetanus in a rural setting of South-Western Nigeria: a ten-year retrospective study.  

UK PubMed Central (United Kingdom)

We review the records of 79 tetanus patients in two hospitals (one tertiary and one secondary level) in Owo, Ondo state, Nigeria from 1997 to 2006. The male: female ratio was 3:1. Ages were 14-70 years (mean 33.25 years, SD ±16.76). The overall case fatality rate (CFR), 32.91%, did was not significantly different in the two hospitals. CFR for men was 32.10% and for women 35.29%. The main factor indicative of bad prognosis was a short hospitalization period. It was observed that 30.38% of our patients were discharged against medical advice (DAMA), that financial constraint was the underlying problem in 50% of cases, and that the trend of DAMA occurred at the two study sites. This DAMA phenomenon could pose a great danger to the eradication of this vaccine preventable disease in rural areas.

Adekanle O; Ayodeji O; Olatunde L

2009-01-01

136

The Result of The Treatment of Infantile Spasm After Two Year Follow-Up Review Of 45 Cases in Ten Past Years  

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Full Text Available In the past ten years, 45 cases of infantile spasm treated in our center. From these patients, 15 cases received only steroid, other 15 cases only clonazepam, and the rest, a combination of clonazepam and steroid. All patients were observed for two years. This is a retrospective study, the data being extracted from patients record. A number of patients were treated in ambulatory and the others were patients of the hospital. The result of comparison of optimal control of seizures are as follow: 1) In only steroid group 27 percent of the patients were free of seizure, 2) In only clonazepam group 28 percent showed no seizure, 3) in combined clonazepam and steroid group 39% were seizure-free. Based on this trial we believe that treatment of infantile spasm with combined steroid and clonazepam is better than any of them alone. Considering these results, we believe that the treatment of infantile spasm with a combination of steroid and clonazepam is preferable to these drugs.

A Nasirian

2001-01-01

137

Density functional study of bare gold clusters: the ten-vertex neutral system.  

UK PubMed Central (United Kingdom)

Four novel Au10 structures have been located by means of density functional methods and their geometry and electronic structure are discussed. Furthermore, the behavior of less extensive basis sets in conjunction with the B3PW91 functional is compared to a highly accurate and more extensive energy-consistent scalar-relativistic pseudopotential and basis set for neutral ten-vertex gold clusters. The values obtained for several structural parameters for known and novel optimized Au10 systems are discussed.

Sárosi MB; Petrar PM; King RB

2013-10-01

138

New polyethylenes in total hip replacement: A ten- to 12-year follow-up study.  

UK PubMed Central (United Kingdom)

Between 1999 and 2001, 90 patients underwent total hip replacement using the same uncemented acetabular and femoral components with a 28 mm metallic femoral head but with prospective randomisation of the acetabular liner to either Durasul highly cross-linked polyethylene or nitrogen-sterilised Sulene polyethylene. We assessed 83 patients at a minimum follow-up of ten years. Linear penetration of the femoral head was estimated at six weeks, six and 12 months and annually thereafter, using the Dorr method, given the non-spherical shape of the acetabular component. There was no loosening of any component; only one hip in the Sulene group showed proximal femoral osteolysis. The mean penetration of the femoral head at six weeks was 0.08 mm (0.02 to 0.15) for the Durasul group and 0.16 mm (0.05 to 0.28) for the Sulene group (p = 0.001). The mean yearly linear penetration was 64.8% lower for the Durasul group at 0.05 mm/year (sd 0.035) for the Sulene group and 0.02 mm/year (sd 0.016) for the Durasul (p < 0.001). Mean linear femoral head penetration at ten years was 61% less in the Durasul than Sulene group. Highly cross-linked polyethylene gives excellent results at ten years.

García-Rey E; García-Cimbrelo E; Cruz-Pardos A

2013-03-01

139

[Efficiency of TENS treatment in hemiplegic shoulder pain: a placebo controlled study].  

UK PubMed Central (United Kingdom)

OBJECTIVE: To evaluate the efficacy of transcutaneous electrical nerve stimulation (TENS) therapy on shoulder pain and upper extremity functions in hemiplegic patients. MATERIAL-METHODS: Total of 19 hemiplegic patients with shoulder pain were as consecutive randomly assigned into two groups. TENS was applied in group 1 (n = 10) for 20 minutes and group 2 (n = 9) received placebo stimulation. Conventional rehabilitation program were applied total 15 sessions during a period of 3 week in both groups.The visual analog scale (VAS) to evaluate shoulder pain, Barthel Index (BI) for daily-life activities (DLA) were used. The shoulder passive range of motions (PROMs) and Brunnstrom stage of motor recovery were measured. RESULTS: Clinical parameters were similar at baseline. In both groups, significant improvements were observed in VAS and BI (group 1: p<0.001; group 2: p<0.05). In VAS (p<0.001), and BI (p<0.05) were showed significant improvements in favor of group 1, when compared with the groups. In PROMs of abduction and external rotation of shoulder significant improvements were observed in only group 1 (p<0.001, p<0.001 respectively). There was not any significant improvement on Brunnstrom stage of motor recovery in both groups (p>0.05). CONCLUSION: In conclusion that TENS therapy together with conventional rehabilitation could be used as a good alternative therapy in patients with hemiplegic shoulder pain.

Ekim A; Arma?an O; Oner C

2008-01-01

140

Experimental Studies on Particle and Radionuclide Production Cross Sections for Tens of MeV Neutrons and Protons  

International Nuclear Information System (INIS)

Experimental studies are described for (1) differential thick-target neutron yields and double-differential neutron emission cross sections for (p,n) and (d,n) reactions (2) fragment production reactions, and (3) radionuclide production for neutron- and proton-induced reactions in the tens of MeV region and upgrading of the 7Li(p,n) neutron source

2005-05-24

 
 
 
 
141

Case Study: A Case of Cerebrovascular Accident  

Science.gov (United States)

This is a case study for undergraduate students in anatomy, physiology, and/or anatomy and physiology. In particular this case study explores anatomy and physiology of the brain. Users of the National Center for Case Study Teaching in Science will be required to register (free) to gain access to the answer key (and must be of teaching status to receive the key). Included in the resource are the case overview, objectives, case study, teaching notes and answer key.

David Dean (Spring Hill College Biology)

2005-12-02

142

[Shoulder dystocia: a ten-year descriptive study in a level-III maternity unit].  

UK PubMed Central (United Kingdom)

OBJECTIVE: Shoulder dystocia is one of the most dreadful complications of vaginal deliveries. The aim of this observational study was to evaluate risk factors of dystocia, maternal and neonatal complications and recurrent risk factors. PATIENTS AND METHODS: Sixty-six cases of shoulder dystocia occurring between January 1998 and August 2008 in our university hospital were identified. Demographic data, labor management, management of the shoulder dystocia and neonatal outcome were recorded. RESULTS: The incidence of shoulder dystocia was 0.3%. Multiparity, weight gain greater than 12 kg, and post-term delivery were more present in our study group. McRoberts' manoeuver and symphyseal pressure were first realised. Brachial plexus injuries affected 9% of neonates with skeletal fractures in 7.5% of cases. Maternal morbidity was evaluated at about 8%. Twenty per cent had a recurrent shoulder dystocia. DISCUSSION AND CONCLUSION: Shoulder dystocia is an obstetric emergency which requires a prompt management of trained personnel. Despite the difficulty of being able to prevent shoulder dystocia, training the obstetric staff could probably improve management of shoulder dystocia.

Lima S; Chauleur C; Varlet MN; Guillibert F; Patural H; Collet F; Seffert P; Chêne G

2009-04-01

143

Spectrum of hemoglobinopathies in the state of Orissa, India: a ten years cohort study.  

UK PubMed Central (United Kingdom)

OBJECTIVES: i) To determine the pattern of spectrum of hemoglobinopathies in the state of Orissa, ii) To find the ethnic groups at high risk of hemoglobinopathies, iii) Geographical distribution of hemoglobinopathies, and iv). To know epidemiological aspects of hemoglobinopathy cases in Orissa. MATERIAL AND METHODS: One thousand fifteen cases of anemia were analysed referred from different peripheral hospitals and Medical Colleges and Hospitals of Orissa state for diagnosis and counseling during 1994 to 2003. About 2-3 ml. intravenous blood samples were collected after obtaining informed consent from each individual. Hematological indices were measured using MS4 Cell Counter. Background data of each individual were recorded like age, sex, caste, place of origin, consanguinity, etc. Hemoglobin electrophoresis was carried out on CAM in Tris-EDTA-Borate buffer at pH 8.9 and quantification of A2 fraction of hemoglobin by elution method. The value more than 3.5% of A2 fraction of hemoglobin was taken as cut off point for beta-thalassemia trait and more than 10% as Hb E. Hb electrophoresis in acidic medium (pH 6.2) was also carried out to confirm Hb D or E band. Estimation of fetal hemoglobin was done. Family studies were carried out to confirm the diagnosis. RESULTS: Most common hemoglobinopathies observed out of 1015 cases were: sickle cell trait (29.8%), sickle cell disease (7.5%), sickle cell-beta-thalassemia (1.7%), beta-thalassemia trait (18.2%), thalassemia major (5.3%), thalassemia intermedia (0.9%), Hb E trait (0.9%), Hb E disease (0.3%), E-beta-thalassemia (0.7%), Hb D trait (0.2%) and SD disease (0.2%). Sickle cell disorders with high level of fetal hemoglobin were common in general castes (0.3-20.7%), scheduled castes (0-8.9%) and scheduled tribals (0-5.5%). Transfusion dependent beta-thalassemia syndrome was prevalent in Brahmin, Karan, Khandyat, Teli, etc. Most of the cases belong to Anugul district, followed by Khurda, Nayagarh, Phulbani, Cuttack, Jajpur, Dhenkanal, Ganjam, Keonjhar, Mayurbhanj, etc. CONCLUSIONS: The heterogeneous population is harbouring almost all major hemoglobinopathies in general castes, scheduled castes and tribes, belonging to Coastal and South-Western regions of Orissa. This study provides for the first time a comprehensive database on the pattern of spectrum of hemoglobinopathies in Orissa.

Balgir RS

2005-12-01

144

Pathology Case Study: Hydrocephalus  

Science.gov (United States)

The University of Pittsburgh School of Medicine's Department of Pathology has compiled a series of case studies to help both students and instructors. In this particular study an otherwise healthy 9 month old infant is presented with hydrocephalus. The case study provides test results and images along with microscopic photos and description. Clicking on the final diagnosis provides a thorough explanation of the diagnosis and treatment.

2007-08-20

145

Equity in HIV testing: evidence from a cross-sectional study in ten Southern African countries.  

UK PubMed Central (United Kingdom)

BACKGROUND: HIV testing with counseling is an integral component of most national HIV and AIDS prevention strategies in southern Africa. Equity in testing implies that people at higher risk for HIV such as women; those who do not use condoms consistently; those with multiple partners; those who have suffered gender based violence; and those who are unable to implement prevention choices (the choice-disabled) are tested and can have access to treatment. METHODS: We conducted a household survey of 24,069 people in nationally stratified random samples of communities in Botswana, Lesotho, Malawi, Mozambique, Namibia, South Africa, Swaziland, Tanzania, Zambia, and Zimbabwe. We asked about testing for HIV in the last 12 months, intention to test, and about HIV risk behaviour, socioeconomic indicators, access to information, and attitudes related to stigma. RESULTS: Across the ten countries, seven out of every ten people said they planned to have an HIV test but the actual proportion tested in the last 12 months varied from 24% in Mozambique to 64% in Botswana. Generally, people at higher risk of HIV were not more likely to have been tested in the last year than those at lower risk, although women were more likely than men to have been tested in six of the ten countries. In Swaziland, those who experienced partner violence were more likely to test, but in Botswana those who were choice-disabled for condom use were less likely to be tested. The two most consistent factors associated with HIV testing across the countries were having heard about HIV/AIDS from a clinic or health centre, and having talked to someone about HIV and AIDS. CONCLUSIONS: HIV testing programmes need to encourage people at higher risk of HIV to get tested, particularly those who do not interact regularly with the health system. Service providers need to recognise that some people are not able to implement HIV preventive actions and may not feel empowered to get themselves tested.

Mitchell S; Cockcroft A; Lamothe G; Andersson N

2010-01-01

146

Density functional study of bare gold clusters: the ten-vertex neutral system.  

Science.gov (United States)

Four novel Au10 structures have been located by means of density functional methods and their geometry and electronic structure are discussed. Furthermore, the behavior of less extensive basis sets in conjunction with the B3PW91 functional is compared to a highly accurate and more extensive energy-consistent scalar-relativistic pseudopotential and basis set for neutral ten-vertex gold clusters. The values obtained for several structural parameters for known and novel optimized Au10 systems are discussed. PMID:23963713

Sárosi, Menyhárt B; Petrar, Petronela M; King, R Bruce

2013-08-22

147

Laos case study  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Peuan Mit is a Lao organization working to address the needs of children and youth living and working on the streets. This case study outlines how a trusted and strong relationship with local police provides mutual benefit.

Tenni, Brigitte; Sychareun, Vanphanom

148

Rheumatic symptoms in childhood leukaemia and lymphoma-a ten-year retrospective study.  

UK PubMed Central (United Kingdom)

BACKGROUND: The initial symptoms of childhood leukaemia and lymphoma are often similar to those of juvenile idiopathic arthritis (JIA). In our study, we analyzed the frequency and characteristics of musculoskeletal complaints as the initial presenting symptoms of newly diagnosed leukaemia and lymphoma patients in the past 10 years in our clinic. METHODS: Using the Hungarian Tumour Register, we performed a retrospective analysis of the medical records of 166 new leukaemia and 95 new lymphoma pediatric patients treated from 1999 to 2009 at the 2nd. Dept. of Paediatrics of the Semmelweis University in Budapest. RESULTS: Twenty percent of the leukaemic (33 children) and 2% of the lymphoma patients (2 children) had musculoskeletal symptoms at first presentation. Two-thirds of both groups of patients had other general symptoms like fever and/or fatigue. The hip was the most frequently affected joint (7/33) in the leukaemic patients. Twenty-four percent of all the children had been previously evaluated by an orthopaedist; 12% had visited another rheumatologist prior to diagnosis. Imaging had been done in an unexpectedly low number of patients prior to referral to our unit (radiographs: 16 or 48%, ultrasound: 5 patients or 15%). Radiographs of the affected joints were abnormal in only one case (1/16, 6%). The joint ultrasound was abnormal in only three children of 5 studied (3/5, 60%). Anaemia (26/32, 6%), thrombocytopenia (78%) and LDH elevation (3--4 times the normal count) were frequent in the leukaemic patients. Half of the cases had a normal leukocyte count. The lymphoma group had similar results. Two patients of the leukaemia group received steroid treatment before the final diagnosis. Severe pain out of proportion to physical findings is another clue. CONCLUSIONS: Haematologic malignancies must be excluded before initiation of therapy for childhood arthritis among children presenting with musculoskeletal signs and symptoms, particularly in atypical cases. Malignancies are to be suspected when pain is disproportionately severe compared to the physical examination findings, and when anaemia, thrombocytopenia, and an elevated LDH level are present. Diagnosing leukaemia early is important because the use of steroids and immunosuppressive medications may mask and delay its diagnosis. Additionally, pre-treatment of presumed JIA patients with these drugs who eventually are diagnosed to have a malignancy may lead to the malignancy being steroid-resistant and more difficult to treat.

Zombori L; Kovacs G; Csoka M; Derfalvi B

2013-05-01

149

Yield potential study of meristem derived plantlets of ten potato varieties (Solanum tuberosum L.)  

Directory of Open Access Journals (Sweden)

Full Text Available Ten exotic potato varieties (var. All Blue, All Red, Cardinal, Diamant, Daisy, Granulla, Green Mountain, Japanese Red, Pontiac and Summerset) were used in this experiment during November 2010 to January 2011. In vitro grown 21 day old plantlets having 4-5 cm long with good root system were transferred and established in the trial field for investigating yield performance. Tuber number and weight from 10 randomly selected potato plants of each variety were recorded. The highest tuber number (57.52) per plant was recorded in var. Daisy and the lowest tuber number (8.82) per plant was recorded in red varieties. On the other hand, total tuber weight per plant was highest (344.60g) in var. Diamant whereas, total tuber weight per plant was lowest (65.05 g) in var. All blue varieties showed the most potential yield in this experiment.

M Rezaul Karim, Hafizur Rahman, Tanziman Ara, MST Rehena Khatun, M Monzur Hossain, AKM Rafiul Islam

2011-01-01

150

Henoch-Schönlein purpura outcome in children: A ten-year clinical study  

Directory of Open Access Journals (Sweden)

Full Text Available Introduction. Henoch-Schönlein purpura (HSP) is the most common vasculitis of childhood. It is characterized by symptoms including nonthrombocytopenic purpura, abdominal pain, haematuria/proteinuria, and arthralgia/arthritis. The pleiomorphism of clinical signs in HSP could be confused with other conditions or other vasculitis forms. Objective. Evaluation of HSP clinical presentation, the onset and severity of renal manifestation in affected children and their outcome. Methods. A retrospective study of 49 patients diagnosed with HSP was conducted from September 1999 to September 2009. Children with severe renal manifestations (nephrotic range proteinuria, with or without nephrotic or nephritic syndrome) have undergone kidney biopsy. Results. Twenty-five patients developed renal manifestations after onset of the disease. In our study child’s older age was a risk factor for association with HSP nephritis. Six of the patients required kidney biopsy. They were successfully treated with various immunosuppressive protocols, as well as three of nine patients with nephrotic range proteinuria. Two patients developed most severe form of HSP nephritis, nephrotic-nephritic syndrome with histology grade IIIb/IVb. During the study period (average follow-up 6 years), all patients had a normal global renal function with mild proteinuria in only two cases. The prognosis of renal involvement was better than reports from other patient series. Conclusion. Long-term morbidity of HSP is predominantly attributed to renal involvement. During the study period, no patient had renal insufficiency or end stage renal disease after various combinations of immunosuppressive treatment. It is recommended that patients with HSP nephritis are followed for longer periods of time with a regular measurement of renal function and proteinuria.

Spasojevi?-Dimitrijeva Brankica; Kosti? Mirjana; Peco-Anti? Amira; Kruš?i? Divna; Cvetkovi? Mirjana; Miloševski-Lomi? Gordana; Paripovi? Dušan

2011-01-01

151

Graves' disease in Saudi Arabia: a ten-year hospital study.  

UK PubMed Central (United Kingdom)

OBJECTIVE: To determine clinical manifestation and mode of treatment of Graves' disease at King Khalid University Hospital Riyadh, Saudi Arabia. METHODS: A retrospective study of all cases of Graves' disease diagnosed at the hospital in the period between January 1995 and December 2004, who received a minimum of two years treatment were included in the study. RESULTS: A total of 194 patients were seen with female: male ratio of 2.9:1 and mean age of 32 +/- 0.9 years. Sixty nine percent of the patients had positive thyroid antibodies. Palpitations, tremors, weight loss and nervousness were the most common presenting manifestations. Forty nine percent of patients were treated with radioiodine, 38% with antithyroid drugs, and 13% underwent subtotal thyroidectomy. CONCLUSION: Clinical manifestations of Graves' disease in our patients distinctly differed from those reported in the West and Pacific Islanders with notable rarity of pretibial myxoedema and hyperpigmentation respectively. We also noted higher male to female ratio and an increasing utility of radioactive iodine therapy while use of antithyroid drugs and surgery are declining.

Malabu UH; Alfadda A; Sulimani RA; Al-Rubeaan KA; Al-Ruhaily AD; Fouda MA; Al-Maatouq MA; El-Desouki MI

2008-06-01

152

Study on dose distributions in a slab phantom irradiated by several tens MeV neutrons  

Energy Technology Data Exchange (ETDEWEB)

From the viewpoint of radiation protection for high and intermediate energy radiation fields such as accelerator facilities, it is important to evaluate the effective dose due to secondary neutrons produced. As for the effective dose evaluation, the accuracy of high energy particle transport code system, however, has not been validated experimentally for intermediate energy neutrons. To establish a method of effective dose evaluation due to several tens MeV neutrons, neutron fluxes and dose distributions in a slab phantom were measured with SSNTDs (Solid State Nuclear Track Detectors), fission counter, TEPC and TEIC using 40- and 65-MeV quasi-monoenergetic neutrons at TIARA of JAERI. The measured distributions were compared with the calculated ones with the HETC-3STEP and MORSE-CG codes. In addition, for the purpose of applying them to the dose evaluation, the energy spectra of source neutrons and energy responses of detectors were determined. As a result, the calculated distributions of neutron flux and absorbed dose within the phantom were in good agreement with the experimental ones, and those of dose equivalent agreed with the measured ones within about 20%. It was found that the effective dose for several tens MeV neutrons could be evaluated with the accuracy of about {+-}20%. Source spectra below 10 MeV were evaluated from the present measurements and calculations. The evaluated ones will be very useful for future experiments and calculations in TIARA because they have not been measured. The energy responses of SSNTDs were evaluated for neutrons of wide energy range, based on the newly developed computation code and the measured responses for neutrons ranging from 100 keV to 65 MeV. (author)

Nakane, Yoshihiro [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

2000-02-01

153

Study on dose distributions in a slab phantom irradiated by several tens MeV neutrons  

International Nuclear Information System (INIS)

[en] From the viewpoint of radiation protection for high and intermediate energy radiation fields such as accelerator facilities, it is important to evaluate the effective dose due to secondary neutrons produced. As for the effective dose evaluation, the accuracy of high energy particle transport code system, however, has not been validated experimentally for intermediate energy neutrons. To establish a method of effective dose evaluation due to several tens MeV neutrons, neutron fluxes and dose distributions in a slab phantom were measured with SSNTDs (Solid State Nuclear Track Detectors), fission counter, TEPC and TEIC using 40- and 65-MeV quasi-monoenergetic neutrons at TIARA of JAERI. The measured distributions were compared with the calculated ones with the HETC-3STEP and MORSE-CG codes. In addition, for the purpose of applying them to the dose evaluation, the energy spectra of source neutrons and energy responses of detectors were determined. As a result, the calculated distributions of neutron flux and absorbed dose within the phantom were in good agreement with the experimental ones, and those of dose equivalent agreed with the measured ones within about 20%. It was found that the effective dose for several tens MeV neutrons could be evaluated with the accuracy of about ±20%. Source spectra below 10 MeV were evaluated from the present measurements and calculations. The evaluated ones will be very useful for future experiments and calculations in TIARA because they have not been measured. The energy responses of SSNTDs were evaluated for neutrons of wide energy range, based on the newly developed computation code and the measured responses for neutrons ranging from 100 keV to 65 MeV. (author)

2000-01-01

154

Accomplishments during young adulthood of children originally diagnosed with minimal cerebral dysfunction: a ten-year follow-up study.  

UK PubMed Central (United Kingdom)

To gather data about the adult accomplishments of persons diagnosed with minimal cerebral dysfunction this retrospective study evaluated 57 subjects at ten-year follow-up. Two-thirds of the subjects graduated from high school with an average of 11.8 years of education. Factors correlating with educational outcome included intelligence quotient, age at initial evaluation, and parental socioeconomic status. Adult accomplishments appear related to intelligence and to the presence of family or behavior problems.

Rogers PT; McLoughlin CS

1997-06-01

155

Ten-year experiences with Tracheostomy at a University teaching hospital in Northwestern Tanzania: A retrospective review of 214 cases  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background Tracheostomy remains a very important life saving surgical procedure worldwide and particularly in our environment where patients present late in upper airway obstruction. Little work has been done on this subject in our environment and therefore it was necessary to conduct this study to describe our own experiences with tracheostomy, outlining the common indications and outcome of tracheostomized patients in our setting and compare our results with those from other centers in the world. Methods This was a 10-year retrospective study which was conducted at Bugando Medical Centre from January 2001 to December 2010. Data were retrieved from patients' files kept in the Medical record department and analyzed using SPSS computer software version 15.0. Ethical approval to conduct the study was obtained from relevant authority before the commencement of the study. Results A total of 214 patients were studied. The male to female ratio was 3.1: 1. The majority of patients were in the 3rd decade of life. The most common indication for tracheostomy was upper airway obstruction secondary to traumatic causes in 55.1% of patients, followed by upper airway obstruction due to neoplastic causes in 39.3% of cases. The majority of tracheostomies (80.4%) were performed as an emergency. Transverse skin crease incision was employed in all the cases. Post-tracheostomy complication rate was 21.5%. Complication rate was significantly higher in emergency tracheostomy than in electives (P Conclusion Upper airway obstruction secondary to trauma and laryngeal tumors still remains the most common indication for tracheostomy in our centre and tracheostomy is still a life saving procedure in the surgical management of airway despite complications which are seen more commonly in paediatric patients. Most of tracheostomy related complications can be avoided by meticulous attention to the details of the technique and postoperative tracheostomy care by skilled and trained staff.

Gilyoma Japhet M; Balumuka Darius D; Chalya Phillipo L

2011-01-01

156

Nuclear medicine case studies  

Energy Technology Data Exchange (ETDEWEB)

This text presents case studies in nuclear medicine which emphasize the diagnosis of the patient's problem rather than the technical performance of the procedure. The book is arranged by organ systems and each section begins with a description of the technique and findings in a normal study.

Wagner, H.N. Jr.

1986-01-01

157

Triacylglycerols in some underutilised tropical seed oils 1. Systematic studies of ten oils  

International Nuclear Information System (INIS)

Triacylglycerols composition of ten lesser known and underutilised tropical seed oils have been determined. The seed oils include Monodora tenuifolia, Monodora myristica, Colocynthis citrullus, Cyperus esculentus, Cucumeropsis edulis, Andenopus breviflorus, Telfairia occidentalis, Blighia sapida, Antiaris africana and Sesame indicum. In the Moreaceae family (M. tenuifolia, M. myristica) the dominant triacylglycerol are OPO/POO, LLO, OOL, and OOO. They accounted for over 60% of the total triacylglycerol content in the oils. In the Cyperaceae family (C. esculentus), OPP/POO, POL and OOO accounted for over 80% of the total triacylglycerol content. In the Cucurbitaceae family, SSP was the dominant triacylglycerol specie in A. breviflorus, while OPO/POO and OOO were the dominant species in C. citrullus and C. edulis. Blighia sapida recorded a different distribution of triacylglycerols composition. PLL occurred at the highest concentration, while other high molecular weight triacylglycerols were also identified in the oil. They include, SSA, OSA, LSA, OAA and LLA. Analysis of A. antiaris oil showed a different pattern in the distribution of the triacylglycerols. LaLaM, MMLa and LaLaLa accounted for about 80% of the total triacylglycerols. This result reflected the fatty acid composition of the oil. Lauric acid (C12:0) and Myristic acid (C14:0) accounted for 71.5% of the total fatty acid. The possible use of the oils as cocoa butter equivalents CBEs and cocoa butter substitutes CBSs are discussed. (author)

2002-01-01

158

Observational study of patient and surgeon preoperative preparation in ten companion animal clinics in Ontario, Canada.  

UK PubMed Central (United Kingdom)

BACKGROUND: Surgical site infections (SSIs) are a recognized risk of any surgical procedure in veterinary medicine. One of the keys to prevention of SSIs is reducing exposure of the surgical site to endogenous and exogenous microbes, beginning in the preoperative period. While guidelines are available for preoperative preparation procedures, there has been no objective investigation of compliance with these recommendations in veterinary practices. The objectives of this pilot study were to describe preoperative patient and surgeon preparation practices in a sample of non-equine companion animal veterinary clinics, and to determine if there were any areas that consistently did not meet current guidelines. RESULTS: Observation of preparation practices was performed in 10 clinics over 9--14 days each using up to 3 small wireless surveillance cameras. Data were coded for 148 surgical patients, and 31 surgeons performing 190 preoperative preparations. When patient hair removal was observed, it was most commonly done using clippers (117/133, 88%), and in only one case was it performed prior to anesthetic induction. Patient contact time with soap ranged from 10-462 s (average of clinic means 75 s, average of clinic medians 67 s), and with alcohol from 3-220 s (average of clinic means 44 s, average of clinic medians 37 s). Alcohol-based hand rub (AHR) was used preoperatively in 2/10 facilities, but soap-and-water hand scrub was most commonly used at all clinics. Proximal-to-distal scrubbing was noted in 95/142 (67%) of soap-and-water scrubs. Contact time during surgeon hand preparation ranged from 7-529 s (average mean 121 s, average median 122 s) for soap-and-water and from 4-123 s (average mean 25 s, average median 19 s) for AHR. No significant changes in practices were identified over time during the observation period. Practices that did not conform to guidelines available in major companion animal surgical textbooks were commonly observed. CONCLUSIONS: Some preoperative preparation practices were relatively consistent between clinics in this study, while others were quite variable. Contact times with preoperative preparatory solutions for both patients and surgeons were often shorter than recommended. Evidence-based guidelines for these procedures in veterinary medicine should be established and implemented in order to help reduce preventable SSIs, while maintaining efficiency and cost-effectiveness.

Anderson ME; Foster BA; Weese JS

2013-10-01

159

Ten-year risk of second hip fracture. A NOREPOS study.  

UK PubMed Central (United Kingdom)

BACKGROUND: Second hip fracture risk is elevated after the first, however whether risk differs with age, by sex or over time is not well known. OBJECTIVE: To examine the risk of second hip fracture by sex, age and time after first hip fracture. DESIGN: Data on all hip fractures in subjects 50 years and older and treated in Norwegian hospitals during 1999-2008 were retrieved. Surgical procedure codes and additional diagnosis codes were used to define incident fractures. Survival analyses with and without adjustment for competing risk of death were used to estimate the risk of second hip fracture. RESULTS: Among the 81,867 persons who sustained a first hip fracture, 6161 women and 1782 men suffered a second hip fracture during follow-up. The overall age-adjusted hazard ratio (HR) of a second hip fracture did not differ between the sexes (women versus men, HR=1.03; 95% confidence interval (CI): 0.98-1.09). Taking competing risk of death into account, the corresponding age-adjusted HR of a second hip fracture was 1.40 (95% CI: 1.33-1.47) in women compared to men. The greater risk in women was due to a higher mortality in men. Based on competing risk analyses, we estimate that 15% of women and 11% of men will have suffered a second hip fracture within 10 years after the first hip fracture. The ten-year cumulative incidence was above 10% in all age-groups, except in men 90 years and older. CONCLUSION: Fracture preventive strategies have a large potential in both women and men who suffer their first hip fracture due to the high risk of another hip fracture.

Omsland TK; Emaus N; Tell GS; Ahmed LA; Center JR; Nguyen ND; Gjesdal CG; Forsmo S; Schei B; Søgaard AJ; Meyer HE

2013-01-01

160

Different mechanisms for the short-term effects of real versus sham transcutaneous electrical nerve stimulation (TENS) in patients with chronic pain: a pilot study.  

UK PubMed Central (United Kingdom)

Transcutaneous electrical nerve stimulation (TENS) has existed since the early 1970s. However, randomized placebo controlled studies show inconclusive results in the treatment of chronic pain. These results could be explained by assuming that TENS elicits a placebo response. However, in animal research TENS has been found to decrease hyperalgesia, which contradicts this assumption. The aim of this study is to use quantitative sensory testing to explore changes in pain processing during sham versus real TENS in patients with chronic pain. Patients with chronic pain (N = 20) were randomly allocated to real TENS or sham TENS application. Electrical pain thresholds (EPTs) were determined inside and outside the segment stimulated, before and after the first 20 minutes of the intervention, and after a period of 10 days of daily real/sham TENS application. Pain relief did not differ significantly for real versus sham TENS. However, by comparing time courses of EPTs, it was found that EPT values outside the segment of stimulation increased for sham TENS, whereas for real TENS these values decreased. There were, however, no differences for EPT measurements inside the segment stimulated. These results illustrate the importance of including mechanism-reflecting parameters in addition to symptoms when conducting pain research.

Oosterhof J; Wilder-Smith OH; Oostendorp RA; Crul BJ

2012-01-01

 
 
 
 
161

Laos case study  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Peuan Mit is a Lao organization working to address the needs of children and youth living and working on the streets. This case study outlines how a trusted and strong relationship with local police provides mutual benefit.

Tenni Brigitte; Sychareun Vanphanom

2012-01-01

162

HI-TENS Reduces Moderate-to-Severe Pain Associated With Most Wound Care Procedures: A Pilot Study.  

UK PubMed Central (United Kingdom)

This study systematically examined pain associated with wound care procedures (WCPs) and evaluated the effectiveness of high-intensity transcutaneous electrical nerve stimulation (HI-TENS) for reducing this pain in a two-phase design. Phase 1 (N = 57) examined patient, wound, and procedural factors, as well as analgesic intake, associated with WCPs. Pain during the WCPs was rated on a 0-10 numerical scale. Subjects reported a mean pain of 6.0 (standard deviation 3.04) during Phase 1, with 43 (75.4%) subjects experiencing moderate or severe pain (i.e., ?4). Subjects who received opioid and/or nonopioid analgesia 1 hr before or during the WCPs (36.8%) reported significantly higher pain levels than those who had not received analgesia (p = .013). In Phase 2, 23 subjects with ?4 pain during Phase 1 had HI-TENS applied to the area surrounding the wound during the WCPs. HI-TENS significantly reduced WCP pain by a mean of 2.0 (±2.31; effect size = 0.67; p = .001). This effect was significant for subjects with severe Phase 1 pain (i.e., ?8; effect size = 1.00; p = .007) but not for subjects with moderate Phase 1 pain (i.e., 4-7; effect size = 0.40; p = .053). These findings demonstrate that pain during WCPs is a significant problem, that nurses appropriately administer analgesics but these are not sufficient, and that using HI-TENS may further reduce pain, particularly in patients experiencing severe WCP pain.

Gardner SE; Blodgett NP; Hillis SL; Borhart E; Malloy L; Abbott L; Pezzella P; Jensen M; Sommer T; Sluka KA; Rakel BA

2013-08-01

163

Die invloed van wanpersepsies ten opsigte van die geskiedenis van Suid-Afrika op grondeise: Die BaPhalane ba Ramokoka grondeis as gevallestudie/ The influence of misperceptions on the history of South Africa: The BaPhalane ba Ramokoka land claim as case study  

Scientific Electronic Library Online (English)

Abstract in english During the past few years, Archaetnos has been involved in various land claims, with a view to collecting historical, anthropological and archaeological information in order to determine the validity of such claims. This was done by doing deeds searches and studying archival material and anthropological literature, followed by a field survey where claimants indicated sites linked to their history and where they were interviewed. In some cases it was clear from the onset t (more) hat misperceptions about South African history pertain. Even when information is correct, there is sometimes chronological chaos and in certain instances so-called "facts" are being fabricated. The above-mentioned information is used by the Land Claims Commission (LCC) to determine the merit of a claim. The lack of knowledge at this institution frequently results in cases being approved for the process even when such approval was clearly based on incorrect information. The land claim of the BaPhalane Ba Ramokoka community is one such example. In the article the reasons for land claims in general are listed. The merit of the BaPhalane claim, as well as the information obtained during the research process, is then discussed against this background. This is, however, not done in detail, as the article insteadfocuses on the general problem created by historical misperceptions. The findings of the research were that although the BaPhalane had a valid claim to at least four of the thirty-two farms listed, they had no valid claim to at least eighteen others. This was confirmed by the court judgement. It is concluded that the lack of knowledge at the Land Claims Commission results in many cases being unnecessarily investigated. This results in high costs, a waste of time and an unproductive system. It is therefore clear that information is required at a much earlier stage during the land claims process.

van Vollenhoven, Anton C.

2012-12-01

164

Fatigue fracture of a forged cobalt-chromium-molybdenum femoral component inserted with cement. A report of ten cases.  

Science.gov (United States)

Ten patients who had had a total hip replacement with a forged cobalt-chromium-molybdenum femoral prosthesis (Precoat or Precoat Plus) inserted with cement were seen with a fatigue fracture of the stem an average of fifty months (range, nineteen to seventy-four months) postoperatively. The average age of the patients was sixty-one years (range, forty-three to seventy-three years), and the average weight was ninety-six kilograms (range, seventy to 130 kilograms). Eight patients had had a primary total hip replacement, and two had had a revision; all of the acetabular components had been inserted without cement. Radiographs that had been made before the fracture were available for four of the eight hips that had had a primary replacement; all four had radiographic evidence of debonding of the cement mantle from the proximal end of the stem. This probably caused exaggerated cantilever bending stresses on the proximal aspect of the stem as the distal end of the stem was well fixed. The radiographs of both hips that had had a revision demonstrated a non-union of the greater trochanter, which had resulted in separation at the cement-bone interface at the proximal portion of the femur before the fracture. Scanning electron micrographs of five of the ten fractured prostheses demonstrated a fatigue fracture that began near the anterolateral corner of the prosthesis, through characters that had been etched on the implant with a laser. Metallurgical analysis indicated subsurface voids or inclusions, or both, immediately under the region that had been etched. This finding is consistent with thermal changes to the microstructure of the alloy that probably caused a focal reduction in the material strength. A high proportion (seven) of the ten stems had a poor cement mantle. Also, of the seven small stems that were used, six had been implanted in patients who weighed more than eighty kilograms, so there was relative undersizing of the prostheses. Early debonding of the proximal end of a Precoat femoral prosthesis from the cement mantle may occur as a result of a thin cement mantle, leading to loosening and possibly to early fatigue fracture of the stem if the distal portion of the stem remains solidly fixed in the distal portion of the cement column. On the basis of our experience, we recommend that patients who have radiographic evidence of a debonded Precoat femoral component should be informed of the risk of fatigue fracture of the stem and be followed closely even though there may be no symptoms of loosening of the femoral component. PMID:9409798

Woolson, S T; Milbauer, J P; Bobyn, J D; Yue, S; Maloney, W J

1997-12-01

165

Pathology Case Study: Headache  

Science.gov (United States)

The Department of Pathology at the University of Pittsburgh Medical Center has compiled a wide range of pathology case studies to aid students and instructors in the medical/health science field. In this case, a 79 year old male with headaches and sinus problems is evaluated. The patient previously had "an inverted papilloma resected." Using the gross description, microscopic description, and images provided, students are encouraged to test their knowledge of pathology and diagnose the patient's medical problem. This is an excellent resource for providing students experience with patient history, lab results and diagnostics.

Nine, Jeff S.

2007-11-28

166

Pathology Case Study: Petechiae  

Science.gov (United States)

This is a case study presented by the University of Pittsburgh Department of Pathology in which a 6-hour-old baby was found to have petechiae. Visitors are given the case description and the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose disease. It is also a helpful site for educators to use to introduce or test student learning in pathology and transfusion medicine.

Lopez-Plaza, Iliana; Qu, Lirong; Nester, Theresa

2008-03-26

167

MIDAS case studies  

Energy Technology Data Exchange (ETDEWEB)

This series of three case studies illustrates the validity and usefulness of MIDAS, a microcomputer-based tool for integrated resource planning under uncertainty. The first, at Union Electric, serves to test and validate the model and to illustrate its use for demand/supply option evaluation. Focusing on nuclear plant life extension, the Virginia Power case demonstrates the model's extensive detail, particularly in the production cost and financial areas, as well as its flexibility in addressing approximately 70 uncertainty scenarios. Puget Sound Power Light, the third case, used MIDAS for the preparation of its integrated resource plan. A 108-endpoint decision tree illustrates the full power of the decision analysis capability.

Brusger, E.C.; Farber, M.A.; Sharpe Hayes, M.M.

1989-07-01

168

Transcutaneous electrical nerve stimulation (TENS) for cancer bone pain.  

UK PubMed Central (United Kingdom)

In the cancer population, painful bony metastases are common, difficult to treat and significantly reduce quality of life. Common treatments include opioid analgesics, bisphosphonates, and radiotherapy; yet these have significant side effects and are not universally effective. Transcutaneous electrical nerve stimulation (TENS) is inexpensive, relatively free from side effects, and widely available. We present a case study of successful TENS therapy in a patient with cancer bone pain and discuss the rationale for using TENS in this setting.

Searle RD; Bennett MI; Johnson MI; Callin S; Radford H

2009-03-01

169

Transcutaneous electrical nerve stimulation (TENS) for cancer bone pain.  

Science.gov (United States)

In the cancer population, painful bony metastases are common, difficult to treat and significantly reduce quality of life. Common treatments include opioid analgesics, bisphosphonates, and radiotherapy; yet these have significant side effects and are not universally effective. Transcutaneous electrical nerve stimulation (TENS) is inexpensive, relatively free from side effects, and widely available. We present a case study of successful TENS therapy in a patient with cancer bone pain and discuss the rationale for using TENS in this setting. PMID:18790599

Searle, Robert D; Bennett, Michael I; Johnson, Mark I; Callin, Sarah; Radford, Helen

2008-09-14

170

Appendicitis: a case study.  

UK PubMed Central (United Kingdom)

The presentation of patients with abdominal pain is a common occurrence in emergency departments. Since there are many potential causes of abdominal pain, diagnosis may be challenging. Accurate history taking and appropriate physical examination are essential to identify potentially life-threatening conditions, such as appendicitis, and ensure prompt treatment. This article presents a case study of a patient presenting with right lower quadrant abdominal pain. Assessment, differential diagnosis and management of the patient are discussed.

Al-Maqbali MA

2013-06-01

171

Case study - Czechoslovakia  

International Nuclear Information System (INIS)

In the lecture Case Study - Czechoslovakia with the sub-title 'Unified System of Personnel Preparation for Nuclear Programme in Czechoslovakia' the actual status and the current experience of NPP personnel training and preparation in Czechoslovakia are introduced. The above mentioned training system is presented and demonstrated by the story of a proxy person who is going to become shift engineer in a nuclear power plant in Czechoslovakia. (orig./HP)

1986-10-23

172

Differences in Drought Tolerance in Ten Chickpea Genotypes I-some Studies on Yield and Yield Components  

Directory of Open Access Journals (Sweden)

Full Text Available Ten genotypes of chickpeas viz. CM-1, CM-2, CM-72, CM-88, CM-1918, C-44, K-850, C-727, Thal White and 86135, were compared for their relative drought tolerance in terms of yield and yield components in field experiment. The genotype CM-2 proved superior to other varieties in almost all the characters studied. It produced maximum number of pods per plant (87.20), gave the highest yield per plant (18.97 g), and more elliptic index of leaf (71.81) under stress conditions. Based on these characters this genotype may be advanced further.

Y. Ali; M.A. Haq; N. Ahmad; S.S. Alam

1998-01-01

173

Self-Report Stability of Adolescent Cigarette Use across Ten Years of Panel Study Data  

Science.gov (United States)

This study is the first to examine adolescent cigarette report stability over 10 years. Six waves of data were utilized from the National Longitudinal Survey of Youth. This study examined internal/logical consistency and external consistency. Report stability was higher for lifetime use reports than the age of onset reports. Wave-by-wave…

Shillington, Audrey M.; Reed, Mark B.; Clapp, John D.

2010-01-01

174

Western Perceptions of Hong Kong Ten Years on: A Corpus-Driven Critical Discourse Study  

Science.gov (United States)

This article studies the Western perceptions of and relations with Hong Kong a decade after the reversion of the sovereignty from Britain to China in 1997. Previous studies have demonstrated that the West had a significantly negative view on the future of Hong Kong with respect to the handover. According to recent observations, however, the…

Cheng, Winnie; Lam, Phoenix W. Y.

2013-01-01

175

The progression of radiological hand osteoarthritis over ten years: a clinical follow-up study.  

Digital Repository Infrastructure Vision for European Research (DRIVER)

The natural history of hand osteoarthritis (OA) is poorly understood. The aim of the study was to ascertain the extent and pattern of radiological progression of hand OA over a 10-year period. A follow-up study was carried out on 169 consecutive patients who initially presented with OA of the hands ...

Harris, PA; Hart, DJ; Dacre, JE; Huskisson, EC; Spector, TD

176

Congenital anomalies among live births in a polluted area. A ten-year retrospective study  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background Congenital anomalies and their primary prevention are a crucial public health issue. This work aimed to estimate the prevalence of congenital anomalies in Brindisi, a city in southeastern Italy at high risk of environmental crisis. Methods This research concerned newborns up to 28 days of age, born between 2001 and 2010 to mothers resident in Brindisi and discharged with a diagnosis of congenital anomaly. We classified cases according to the coding system adopted by the European Network for the Surveillance of Congenital Anomalies (EUROCAT). Prevalence rates of congenital anomalies in Brindisi were compared with those reported by EUROCAT. Logistic regression models were adapted to evaluate the association between congenital anomalies and municipality of residence of the mother during pregnancy. Results Out of 8,503 newborns we recorded 194 subjects with congenital anomalies (228.2/10,000 total births), 1.2 times higher than the one reported by the EUROCAT pool of registries. We observed 83 subjects with congenital heart diseases with an excess of 49.1%. Odds Ratios for congenital heart diseases significantly increased for newborns to mothers resident in Brindisi (OR 1.75 CI 95% 1.30-2.35). Conclusions Our findings indicated an increased prevalence of Congenital Anomalies (especially congenital heart diseases) in the city of Brindisi. More research is needed in order to analyze the role of factors potentially involved in the causation of congenital anomalies.

Gianicolo Emilio Antonio Luca; Bruni Antonella; Rosati Enrico; Sabina Saverio; Guarino Roberto; Padolecchia Gabriella; Leo Carlo; Vigotti Maria Angela; Andreassi Maria Grazia; Latini Giuseppe

2012-01-01

177

Ten-year follow-up of the Oslo Youth Study Smoking Prevention Program.  

UK PubMed Central (United Kingdom)

BACKGROUND: The Oslo Youth Study was designed to demonstrate that health education in schools can result in lowered rates of smoking and alcohol consumption, improved eating patterns, and increased physical activity. The study was conducted from 1979 to 1981 in six schools in Oslo, Norway. This article presents the 10-year follow-up outcomes of the Oslo Youth Study Smoking Prevention Program. METHODS: In the fall of 1989, former Oslo Youth Study participants were contacted through the mail and asked to complete a short questionnaire containing questions regarding smoking behavior. A total of 796 subjects participated (participation rate of 74.0%). RESULTS: Overall, there were no significant effects of the Oslo Youth Study Smoking Prevention Program on the onset of experimental smoking (ever having smoked) or regular smoking (weekly smoking). Significant intervention effects were observed, however, among baseline nonsmoking males; intervention students reported 30% less weekly smoking (35% vs 50%) and 25% greater nonsmoking status (58% vs 44%) in 1989 than did males having attended the reference schools. No treatment effects were observed for females. CONCLUSIONS: The results suggest that the smoking prevention program might have contributed to reduced long-term onset of smoking among participating male subjects.

Klepp KI; Tell GS; Vellar OD

1993-07-01

178

Ten-Year Trend Analysis of Autism Severity: A Nationwide Population-Based Register Study  

Science.gov (United States)

The severity of autism spectrum disorder was strongly related to the education and service outcome. Without a clear profile of autistic population and its change, efforts to understand its nature and improve the quality of service or education will be impossible. The present study aims to describe the over time reported rate of autism severity…

Lin, Jin-Ding; Sung, Chang-Lin; Lin, Lan-Ping; Hsu, Shang-Wei; Chien, Wu-Chien; Su, Sui-Lung; Wu, Jia-Ling

2011-01-01

179

Severe Allergic Reactions to Food in Norway: A Ten Year Survey of Cases Reported to the Food Allergy Register  

Digital Repository Infrastructure Vision for European Research (DRIVER)

The Norwegian Food Allergy Register was established at the Norwegian Institute of Public Health in 2000. The purpose of the register is to gain information about severe allergic reactions to food in Norway and to survey food products in relation to allergen labelling and contamination. Cases are rep...

Ellen Namork; Christiane K. Fæste; Berit A. Stensby; Eliann Egaas; Martinus Løvik

180

Bacteriological profile of community acquired acute bacterial meningitis: A ten-year retrospective study in a tertiary neurocare centre in South India  

Directory of Open Access Journals (Sweden)

Full Text Available Purpose: Ten years retrospective study to evaluate the bacteriological spectrum of community acquired acute bacterial meningitis (CAABM). Methods: Cerebrospinal fluid (CSF) samples from 385 clinically suspected cases of pyogenic meningitis were processed for cell counts, cytospin Gram stain, culture, antigen detection by latex agglutination (LAT) and antibiotic susceptibility test. Eighteen of these CSF samples were also subjected to a polymerase chain reaction (PCR) assay for detection of pneumococcal DNA. Results: The etiological agent could be identified in 284 (73.8%) of the total 385 cases by culture and/or smear and /or LAT. Streptococcus pneumoniae was the predominant pathogen accounting for 238 (61.8%) cases. Haemophilus influenzae and Neisseria meningitidis accounted for 7 (1.8%) and 4 (1%) cases respectively. Other gram negative bacilli, Streptococcus spp. and Staphylococcus aureus were isolated from 19 (4.9%), 9 (2.3%) and 7 (1.8%) cases respectively. Conclusions: Streptococcus pneumoniae remains the major aetiological agent of CAABM both in adults and children in our set-up. No penicillin resistance was detected among the isolates. Further research should focus on preventable aspects of CAABM, especially pneumococcal vaccines, to help reduce the disease burden.

Mani R; Pradhan S; Nagarathna S; Wasiulla R; Chandramuki A

2007-01-01

 
 
 
 
181

The costs of public services for teenage mothers post-welfare reform: a ten-state study.  

UK PubMed Central (United Kingdom)

BACKGROUND: More information is needed on the use and costs of public services by teens after the passage of major national polices in the 1990s. Both the 1996 welfare reform and later changes to the Medicaid program have affected the access of low-income adolescents to public assistance programs. In turn, these changes have affected teenaged mothers and their infants and the costs that taxpayers incur in the 50 states. STUDY QUESTION: What public services do teenage mothers use and what are their costs in the decade after the major policy changes to public assistance programs? How do patterns vary by state? METHODS: This study examines the use by teenage mothers of four public services: cash assistance, Special Supplemental Nutrition Program for Women, Infants, and Children (WIC), food stamps, and Medicaid coverage at delivery. We used 2000 data from the Pregnancy Risk Assessment Monitoring System (PRAMS) to derive rates of use for these four programs in ten states-AK, AL, FL, ME, NY [excluding New York City], NC, OK, SC, WA, and WV. We combined the rates with data on per person and family costs of these four programs to present 'birth-year' costs for a cohort of teenage mothers in the ten states. To provide a baseline from which to measure incremental public service costs to teenage mothers, we also compiled the data for mothers ages 20 to 24 years who did not report births during their teen years. RESULTS: Data from the ten states indicate that the birth-year expenses for teenage mothers for four public programs add up to more than $0.5 billion, and the costs per teenage mother exceed those for older mothers who did not have a teenage birth by almost $1,500. The largest component of these public costs is Medicaid coverage at delivery at 87 percent of the total. If all of the unintended births to teenage mothers in the ten study states were postponed, $75 million in public sector costs would be averted annually. CONCLUSIONS: The use of public programs by teenage mothers remains costly and varies markedly across the ten study states. A key reason for higher costs among teenage mothers than among mothers in their early twenties is their higher rates of enrollment in Medicaid at delivery. This rate of enrollment also varies markedly across the study states. The high level of incremental costs and rate of unintended births to teens indicate that cost-saving interventions could be developed. PUBLIC HEALTH IMPLICATIONS: Data indicate that many teenage pregnancies are unintended. Thus, a clear public health goal should be to implement and evaluate programs aimed at reducing unintended pregnancies among teenagers. Initiatives are needed to help young women make well-informed decisions about sexual activity and other risky behaviors. Insurance coverage is important to all teens and especially to those who are sexually active.

Adams EK; Gavin NI; Ayadi MF; Santelli J; Raskind-Hood C

2009-01-01

182

NOx trade. Case studies  

International Nuclear Information System (INIS)

Some of the questions with respect to the trade of nitrogen oxides that businesses in the Netherlands have to deal with are dealt with: should a business buy or sell rights for NOx emission; which measures must be taken to reduce NOx emission; how much must be invested; and how to deal with uncertainties with regard to prices. Simulations were carried out with the MOSES model to find the answers to those questions. Results of some case studies are presented, focusing on the chemical sector in the Netherlands. Finally, the financial (dis)advantages of NOx trade and the related uncertainties for a single enterprise are discussed

2002-01-01

183

Pathology Case Study: Hemoptysis  

Science.gov (United States)

This is a pulmonary pathology case study presented by the University of Pittsburgh Department of Pathology in which a 55 year old female has spontaneously occurring hemoptysis. Visitors are given both the microscopic and gross descriptions, radiology, including images, and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose. It is also a helpful site for educators to use to introduce or test student learning in pulmonary pathology.

Holst, Valerie; Yousem, Sam

2007-08-28

184

Pathology Case Study: Peritonitis  

Science.gov (United States)

This is a case study presented by the University of Pittsburgh Department of Pathology in which a 26-year-old woman has had a 13-year history of poorly controlled insulin-dependent diabetes mellitus. Visitors are given both the patient history and laboratory results, including images, and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose disease. It is also a helpful site for educators to use to introduce or test student learning in pathology and clinical microbiology.

Pasculle, A. W.; Anhalt, John P.; Torbenson, Michael; Sheaffer, John; Macauley, Robert

2007-10-05

185

Dosimetric Consistency of Co-60 Teletherapy Unit- a ten years Study  

Science.gov (United States)

Objective The goal of the Radiation standards and Dosimetry is to ensure that the output of the Teletherapy Unit is within ±2% of the stated one and the output of the treatment dose calculation methods are within ±5%. In the present paper, we studied the dosimetry of Cobalt-60 (Co-60) Teletherapy unit at Sher-I-Kashmir Institute of Medical Sciences (SKIMS) for last 10 years. Radioactivity is the phenomenon of disintegration of unstable nuclides called radionuclides. Among these radionuclides, Cobalt-60, incorporated in Telecobalt Unit, is commonly used in therapeutic treatment of cancer. Cobalt-60 being unstable decays continuously into Ni-60 with half life of 5.27 years thereby resulting in the decrease in its activity, hence dose rate (output). It is, therefore, mandatory to measure the dose rate of the Cobalt-60 source regularly so that the patient receives the same dose every time as prescribed by the radiation oncologist. The under dosage may lead to unsatisfactory treatment of cancer and over dosage may cause radiation hazards. Our study emphasizes the consistency between actual output and output obtained using decay method. Methodology The methodology involved in the present study is the calculations of actual dose rate of Co-60 Teletherapy Unit by two techniques i.e. Source to Surface Distance (SSD) and Source to Axis Distance (SAD), used for the External Beam Radiotherapy, of various cancers, using the standard methods. Thereby, a year wise comparison has been made between average actual dosimetric output (dose rate) and the average expected output values (obtained by using decay method for Co-60.) Results The present study shows that there is a consistency in the average output (dose rate) obtained by the actual dosimetry values and the expected output values obtained using decay method. The values obtained by actual dosimetry are within ±2% of the expected values. Conclusion The results thus obtained in a year wise comparison of average output by actual dosimetry done regularly as a part of Quality Assurance of the Telecobalt Radiotherapy Unit and its deviation from the expected output data is within the permissible limits. Thus our study shows a trend towards uniformity and a better dose delivery.

Baba, Misba H; Mohib-ul-Haq, M.; Khan, Aijaz A.

2013-01-01

186

Dosimetric Consistency of Co-60 Teletherapy Unit- a ten years Study.  

UK PubMed Central (United Kingdom)

OBJECTIVE: The goal of the Radiation standards and Dosimetry is to ensure that the output of the Teletherapy Unit is within ±2% of the stated one and the output of the treatment dose calculation methods are within ±5%. In the present paper, we studied the dosimetry of Cobalt-60 (Co-60) Teletherapy unit at Sher-I-Kashmir Institute of Medical Sciences (SKIMS) for last 10 years. Radioactivity is the phenomenon of disintegration of unstable nuclides called radionuclides. Among these radionuclides, Cobalt-60, incorporated in Telecobalt Unit, is commonly used in therapeutic treatment of cancer. Cobalt-60 being unstable decays continuously into Ni-60 with half life of 5.27 years thereby resulting in the decrease in its activity, hence dose rate (output). It is, therefore, mandatory to measure the dose rate of the Cobalt-60 source regularly so that the patient receives the same dose every time as prescribed by the radiation oncologist. The under dosage may lead to unsatisfactory treatment of cancer and over dosage may cause radiation hazards. Our study emphasizes the consistency between actual output and output obtained using decay method. METHODOLOGY: The methodology involved in the present study is the calculations of actual dose rate of Co-60 Teletherapy Unit by two techniques i.e. Source to Surface Distance (SSD) and Source to Axis Distance (SAD), used for the External Beam Radiotherapy, of various cancers, using the standard methods. Thereby, a year wise comparison has been made between average actual dosimetric output (dose rate) and the average expected output values (obtained by using decay method for Co-60.). RESULTS: The present study shows that there is a consistency in the average output (dose rate) obtained by the actual dosimetry values and the expected output values obtained using decay method. The values obtained by actual dosimetry are within ±2% of the expected values. CONCLUSION: The results thus obtained in a year wise comparison of average output by actual dosimetry done regularly as a part of Quality Assurance of the Telecobalt Radiotherapy Unit and its deviation from the expected output data is within the permissible limits. Thus our study shows a trend towards uniformity and a better dose delivery.

Baba MH; Mohib-Ul-Haq M; Khan AA

2013-01-01

187

Reproduction and production in a buffaloes farm of the Marche region: a ten-year study  

Directory of Open Access Journals (Sweden)

Full Text Available Water buffalo milk reproductive and productive traits are fundamental to evaluate farm efficiency and dairy economy. Due to the buffalo cows’ long life these aspects are also important to assess the improvement of genetic animal potential and to reach optimal productive performance. Currently this knowledge is critical since the Italian cattle population is decreasing whereas the national buffalo sector is expanding; this trend is partially depending on the reconversion of some dairy cattle’ farms into buffalo cows’ farms. The present investigation was undertaken to study non-genetic factors affecting reproductive parameters and milk production traits in a farm located in a not traditional area for buffalo farming.

S. Mattii; B. Tommei; M. Pasquini

2010-01-01

188

Utility of ten-second uptake periods for kinetic studies of serotonin uptake by intact platelets  

Energy Technology Data Exchange (ETDEWEB)

When washed human platelets accumulate serotonin (5HT), it is possible with the use of formaldehyde fixative to measure uptake over periods as short as 10 seconds. To evaluate the utility of these short times for kinetic studies of 5HT uptake, we have examined the accuracy with which the 10 second uptake rate reflects changes in the extracellular 5HT concentration. The amount of 5HT taken up over a 10 second period appears to be determined by the concentration of 5HT present in the extracellular medium during that time period, and the uptake rate can change rapidly following sudden changes in the extracellular 5HT concentration. However, the extent of inhibition of 5HT uptake in the presence of imipramine of extracellular 5HT concentrations greater than 10-5M is somewhat different depending on whether the 5HT is allowed to accumulate for a 10-second or a 5- or 10-minute uptake period. A 10-second uptake period thus appears to be useful for kinetic studies of initial 5HT uptake velocities under normal conditions, but under inhibitory conditions may give results differing from those obtained with minute-long periods.

Costa, J.L.; Kirk, K.L.; Stark, H.

1981-09-01

189

Tracking cognitive functioning over time: ten-year longitudinal data from a community-based study.  

UK PubMed Central (United Kingdom)

Over 10 years, a community-based sample age 65> or = years, with a starting cohort size of 1,206, was assessed biennially with the Mini-Mental State Exam; the Consortium to Establish a Registry for Alzheimer's Disease battery; Immediate and Delayed Recall of a Story; Verbal Fluency for P and S, Fruits and Animals; Clock Drawing; Temporal Orientation; and Trail Making tests. We report distributions of scores over time, at each wave, in (a) all individuals who were assessed at that wave, whether or not they participated in all waves, and (b) the Survivor subgroup of 425 participants who completed all tests at all 5 waves. Scores and factor structures remained remarkably stable over the study period. The most marked decline over time was seen on the Trail Making tests. As the survivors are de facto a largely healthy and motivated group, their data can be considered population-based healthy norms and may serve as a reference for other studies conducting repeated evaluations using the same tests.

Ratcliff G; Dodge H; Birzescu M; Ganguli M

2003-01-01

190

INTRAVENOUS PULSE CYCLOPHOSPHAMIDE TREATMENT OF LUPUS NEPHRITIS: A RETROSPECTIVE TEN YEARS STUDY  

Directory of Open Access Journals (Sweden)

Full Text Available Nephritis remains an important problem in patients with systemic lupus erythematosus (SLE). We conducted retrospective study to evaluate the efficiency of intravenous pulse cyclophosphamide in lupus nephritis: From 1983 to 1993, we reviewed 133 patients with biopsy proven lupus nephritis, 47 of them excluded because of short period of follow-up or defective laboratory data. Eighty six patients were treated with the following regimens: Sixty patients with intravenous pulse cyclophospham; 13 witli IV pulse methylprednisolone succinate, 8 with cyclosporine, 4 with azathioprine and one with oral prednisolone. Sixteen patients did not respond to IV cyclophosphamide. We evaluated renal biopsy, pretreatment mean arterial pressure (MAP), BUN, creatinine and proteinuria as-prognostic and risk factors of nonresponders. The results of this study showed that diffuse proliferative glomerulonephritis (DPGN) had the poorest outcome and most of nonresponders (11/16), were of DPGN. Tliere was a correlation between initial serum creatinine level and response to IV cyclophosphamide, but there was no correlation between BUN, MAP, degree of proteinuria and response to IV cyclophosphamide. IV pulse cyclophosphamid was more effective than steroid alone in preventing renal failure in lupus nephritis.

R. Ganji.; A. Chobdar .; M. Akhavan B. Broum

1997-01-01

191

Effect of TENS on pain in relation to central sensitization in patients with osteoarthritis of the knee: study protocol of a randomized controlled trial  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background Central sensitization has recently been documented in patients with knee osteoarthritis (OAk). So far, the presence of central sensitization has not been considered as a confounding factor in studies assessing the pain inhibitory effect of tens on osteoarthritis of the knee. The purpose of this study is to explore the pain inhibitory effect of burst tens in OAk patients and to explore the prognostic value of central sensitization on the pain inhibitory effect of tens in OAk patients. Methods Patients with knee pain due to OAk will be recruited through advertisements in local media. Temporal summation, before and after a heterotopic noxious conditioning stimulation, will be measured. In addition, pain on a numeric rating score, WOMAC subscores for pain and function and global perceived effect will be assessed. Patients will be randomly allocated to one of two treatment groups (tens, sham tens). Follow-up measurements will be scheduled after a period of 6 and 12 weeks. Discussion Tens influences pain through the electrical stimulation of low-threshold A-beta cutaneous fibers. The responsiveness of central pain-signaling neurons of centrally sensitized OAk patients may be augmented to the input of these electrical stimuli. This would encompass an adverse therapy effect of tens. To increase treatment effectiveness it might be interesting to identify a subgroup of symptomatic OAk patients, i.e., non-sensitized patients, who are likely to benefit from burst tens. Trial Registration ClinicalTrials.gov: NCT01390285

Beckwée David; De Hertogh Willem; Lievens Pierre; Bautmans Ivan; Vaes Peter

2012-01-01

192

Study of thin-film silicon solar cells at irradiances above ten thousand suns  

International Nuclear Information System (INIS)

[en] We used a tightly focused Gaussian beam of a HeNe laser to study accelerated light-induced degradation (Staebler-Wronski effect) and high photocarrier generation rates in amorphous and microcrystalline silicon thin-film solar cells, at up to13 MW/m2 irradiance. For the experiments, the spot radius was varied from a minimum of 8.6 ?m in the focus to around 1 mm away from the focus. According to COMSOL'' (registered) simulations, even at these high power densities heat diffusion into a glass substrate aided by spreading conduction via the Ag back-contact restricts the temperature rise to less than 14 K. Short-circuit current can be measured directly over a range of irradiances, and the J-V characteristic may be estimated by taking into account shunting by the inactive part of the cell.

2010-11-01

193

Estudo da estimulação elétrica nervosa transcutânea (TENS) nível sensório para efeito de analgesia em pacientes com osteoartrose de joelho/ Study of transcutaneous electrical nerve stimulation (TENS) for the sensory effect of analgesia in patients with knee osteoarthritis  

Scientific Electronic Library Online (English)

Full Text Available Abstract in portuguese INTRODUÇÃO: A osteoartrose de joelho (OAJ) é uma das patologias que mais afetam o aparelho locomotor e interferem de forma considerável nas atividades da vida diária, acometendo os indivíduos em faixa etária variável e em diversos graus e níveis de dor articular. OBJETIVOS: Por causa da importância da articulação do joelho nas atividades locomotoras, os pacientes com osteoartrose de joelho sofrem com a limitação de movimento e rigidez articular. O objetivo d (more) o presente estudo foi avaliar o efeito da estimulação elétrica nervosa transcutânea (TENS) nível sensório para tratamento de dor em pacientes com diagnóstico de osteoartrose de joelho, utilizando escalas de avaliação de dor. MÉTODOS: Foram estudados 10 pacientes com diagnóstico de osteoartrose de joelho, utilizando uma modalidade fisioterapêutica, a eletroterapia, especificamente a (TENS), com parâmetros de 80 Hz e 140 µs, com um total de 10 sessões, 30 minutos para cada sessão, o período total de tratamento compreendeu 4 semanas. Nesse total de 10 sessões, cada paciente foi entrevistado com um questionário na 1ª sessão, na 5ª e na 10ª sessão. Os formulários utilizados foram questionário da dor McGill - Melzack, escala Analógica visual da dor, escala numérica com expressão facial de sofrimento. RESULTADOS: O resultado com a TENS nível sensório para efeito de analgesia mostra que as diferenças foram estatisticamente significativas (p Abstract in english INTRODUCTION: Knee osteoarthritis (KOA) is one of the diseases that most affect the locomotor system and interfere significantly in activities of daily life, affecting individuals at varying ages and in different degrees and levels of joint pain. OBJECTIVES: Because of the importance of the knee joint in locomotor activity, patients with knee osteoarthritis sufferers with limitation of movement, stiffness. The aim of this study was to evaluate the effect of transcutaneous (more) electrical nerve stimulation (TENS) for the sensory processing of pain in patients with osteoarthritis of the knee, using rating scales of pain. METHODS: We studied 10 patients with osteoarthritis of the knee, using a modality physiotherapy, electrotherapy, specifically (TENS), with parameters of 80 Hz and 140 µs, with a total of 10 sessions, 30 minutes for each session, the period Total treatment included 4 weeks in total of 10 sessions, each patient was interviewed with a questionnaire in the first session, on the 5th and 10th session. The forms used were the McGill Pain Questionnaire - Melzack, visual analogue pain scale, numerical scale with facial expression of pain. RESULTS: The result with TENS for the effect of sensory analgesia shows that the differences were statistically significant (p

Morgan, Charles Ricardo; Santos, Franklin Santana

2011-12-01

194

Patient preferences at ten years following initial diagnosis of atrial fibrillation: the Belgrade Atrial Fibrillation Study.  

UK PubMed Central (United Kingdom)

BACKGROUND: Many atrial fibrillation (AF) patients have a poor understanding of the management of this condition. We investigated patient attitudes towards AF and a potential invasive treatment following an average 10-year period of prospective rhythm control in a cohort of newly diagnosed AF patients. METHODS: This was a prospective registry-based study. At the regular annual visit in 2007, patients were asked at random to answer several AF-related questions. RESULTS: Of 390 patients, 277 (71.0%) reported symptom reduction over time, but only 45 (11.5%) reported that they had "got used" to AF; 201 patients (51.5%) stated they would always prefer sinus rhythm, and 280 (71.2%) would accept an invasive AF treatment. Independent predictors for choosing an invasive procedure were younger age, impaired career/working capacity, and male gender (all P < 0.05). CONCLUSION: Our findings suggest that most AF patients prefer sinus rhythm and would readily accept an invasive procedure if it offered the possibility of a cure for their AF.

Potpara TS; Polovina MM; Mujovic NM; Kocijancic AM; Lip GY

2013-01-01

195

Apathy in first episode psychosis patients: a ten year longitudinal follow-up study  

DEFF Research Database (Denmark)

BACKGROUND: Apathy is a common symptom in first episode psychosis (FEP), and is associated with poor functioning. Prevalence and correlates of apathy 10 years after the first psychotic episode remain unexplored. OBJECTIVE: The aims of the study were twofold: 1) to examine prevalence and predictors of apathy at 10 years, and 2) to examine the relationship between apathy at 10 years and concurrent symptoms, functioning and outcome, including subjective quality of life. METHODS: Three-hundred-and-one patients with FEP were included at baseline, 186 participated in the 10 year follow-up. Of these, 178 patients completed the Apathy Evaluation Scale (AES-S-Apathy). Patients were classified as having apathy (AES-S-Apathy?27) or not. The relationship between apathy and baseline variables (Demographics, Diagnosis, Duration of Untreated Psychosis), measures of symptomatology (Positive and Negative Syndrome Scale, Calgary Depression Scale for Schizophrenia), functioning (Global Assessment of Functioning Scale, Strauss Carpenter Level of Functioning Scale) and subjective quality of life (Lehman's Quality of Life Interview) were estimated through correlation analyses and blockwise multiple hierarchical regression analysis. RESULTS: Nearly 30% of patients met the threshold for being apathetic at follow-up. No baseline variables predicted apathy significantly at 10 years. Apathy was found to contribute independently to functioning and subjective quality of life, even when controlling for other significant correlates. CONCLUSIONS: Apathy is a common symptom in a FEP cohort 10 years after illness debut, and its presence relates to impaired functioning and poorer subjective quality of life.

Simonsen, Erik; Evensen, Julie

2012-01-01

196

Ten-year mortality study of the population involved in the Seveso incident in 1976  

Energy Technology Data Exchange (ETDEWEB)

In 1976, an accidental explosion in a plant near Seveso, Italy, caused the contamination of a populated area by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). The area was subdivided into three zones (A, B, and R) having decreasing mean levels of TCDD soil contamination. This study examines the mortality between 1976 and 1986 among the subjects, aged 20-74 years, who were resident in the area since the accident (n = 556 in zone A, n = 3,920 in zone B, n = 26,227 in zone R). Subjects' exposure was classified by residence. A referent cohort of 167,391 subjects who lived in the immediate surroundings was concurrently examined. Vital status ascertainment was successful for over 99% of the subjects. Increased mortality from cardiovascular causes was found; incident-related stressors were considered more relevant to increased mortality than was TCDD exposure. Mortality from several cancers was elevated. The increases in biliary cancer (females), brain cancer, and lymphatic and hemopoietic neoplasms (particularly leukemia in males) did not appear to result from chance, confounding, or information/comparison bias. However, no definite patterns related to exposure classification were apparent. Merely suggestive increases in soft tissue tumors and melanoma were also noted. Liver and breast cancer mortality tended to be below expectations. Interpretation is hampered by the short observation period, small number of deaths from certain causes, and poor exposure definition. Further research is in progress.

Bertazzi, P.A.; Zocchetti, C.; Pesatori, A.C.; Guercilena, S.; Sanarico, M.; Radice, L.

1989-06-01

197

The rural rotation in a medical technology program: a ten-year retrospective study.  

UK PubMed Central (United Kingdom)

OBJECTIVE: This study evaluated the effectiveness of a rural rotation as a tool to recruit medical technology program graduates to medically underserved areas. DESIGN: A paper survey was distributed to all 1994 - 2003 graduates of the West Virginia University Medical Technology Program. SETTING: The survey was mailed to the graduates' homes. PATIENTS OR OTHER PARTICIPANTS: Ninety-four of the two hundred six surveys were returned for a response rate of 45.6%. INTERVENTIONS: Surveys were mailed in January 2004. MAIN OUTCOME MEASURES: Responses to questions regarding choice of site for rural rotation, whether or not a job was offered at the rural site, and whether the graduate subsequently worked at a rural site were tabulated. Responses to questions concerning whether the rotation helped the respondent to appreciate the needs of rural health facilities and whether the rotation resulted in a greater interest in working in a rural area were tabulated. Responses were also tabulated for questions about the value of the rural rotation to the respondent's education and whether the rural rotation was recommended for future students. RESULTS: Of respondents, 70.2% chose their rural rotation sites due to proximity to their homes and 38.3% were offered jobs at their rural rotation sites. 50% of all respondents subsequently worked at a rural site. Of respondents, 73.4% indicated strong agreement that the rotation helped them appreciate the needs of the rural facility, and 37.2% indicated agreement with becoming more interested in working at a rural site. Of respondents, 65% indicated that the rural rotation was beneficial and that they would recommend it to future students. CONCLUSION: Results of the survey suggest that a prior rural affinity is a factor associated with selection of rural sites for medical technology program graduates. The survey results also suggest that a rural rotation during medical technology education is beneficial to individuals, including those who elect not to go to rural sites after graduation. ABBREVIATIONS: Health professions shortage areas (HPSAs) nurse practitioners (NP) medically underserved areas (MUAs) West Virginia Rural Health Education Partnerships (WVRHEP).

Kirby BA

2007-01-01

198

NOx trade. Case studies; NOx handel. Case studies  

Energy Technology Data Exchange (ETDEWEB)

Some of the questions with respect to the trade of nitrogen oxides that businesses in the Netherlands have to deal with are dealt with: should a business buy or sell rights for NOx emission; which measures must be taken to reduce NOx emission; how much must be invested; and how to deal with uncertainties with regard to prices. Simulations were carried out with the MOSES model to find the answers to those questions. Results of some case studies are presented, focusing on the chemical sector in the Netherlands. Finally, the financial (dis)advantages of NOx trade and the related uncertainties for a single enterprise are discussed. [Dutch] Nu NOx-handel serieuze vormen lijkt aan te gaan nemen in het Nederlandse milieubeleid, zullen bedrijven hun positie moeten gaan bepalen. De primaire vragen die daarbij spelen zijn: moet een bedrijf straks NOx-rechten kopen, verkopen; hoever moet het bedrijf gaan met het treffen van reductie maatregelen; moet een bedrijf aansturen op het eigen bedrijfsplafond of zich (mede) richten op externe; welke investeringen moeten worden gedaan; en hoe moet er worden omgegaan met de huidige onzekerheid qua prijsstelling. Op basis van het in het VER-onderzoek opgebouwde gegevensbestand zijn met het MOSES-model (Model On Sustainable Environmental economic Scenarios) een aantal simulaties uitgevoerd om inzicht te krijgen in mogelijke antwoorden op de bovenstaande vragen. Allereerst wordt ingegaan op enkele principes bij NOx-handel, vervolgens wordt een casestudie gepresenteerd voor de chemische sector in Nederland, waarbij per bedrijf de handelspositie wordt gesimuleerd. Ten slotte wordt voor een individuele onderneming nagegaan welke voor- en nadelen (in financiele zin) er aan NOx-handel kunnen kleven en met welke onzekerheden rekening moet worden gehouden.

Jantzen, J.

2002-02-13

199

Agreement among Healthcare Professionals in Ten European Countries in Diagnosing Case-Vignettes of Surgical-Site Infections  

Science.gov (United States)

Objective Although surgical-site infection (SSI) rates are advocated as a major evaluation criterion, the reproducibility of SSI diagnosis is unknown. We assessed agreement in diagnosing SSI among specialists involved in SSI surveillance in Europe. Methods Twelve case-vignettes based on suspected SSI were submitted to 100 infection-control physicians (ICPs) and 86 surgeons in 10 European countries. Each participant scored eight randomly-assigned case-vignettes on a secure online relational database. The intra-class correlation coefficient (ICC) was used to assess agreement for SSI diagnosis on a 7-point Likert scale and the kappa coefficient to assess agreement for SSI depth on a three-point scale. Results Intra-specialty agreement for SSI diagnosis ranged across countries and specialties from 0.00 (95%CI, 0.00–0.35) to 0.65 (0.45–0.82). Inter-specialty agreement varied from 0.04 (0.00–0.62) in to 0.55 (0.37–0.74) in Germany. For all countries pooled, intra-specialty agreement was poor for surgeons (0.24, 0.14–0.42) and good for ICPs (0.41, 0.28–0.61). Reading SSI definitions improved agreement among ICPs (0.57) but not surgeons (0.09). Intra-specialty agreement for SSI depth ranged across countries and specialties from 0.05 (0.00–0.10) to 0.50 (0.45–0.55) and was not improved by reading SSI definition. Conclusion Among ICPs and surgeons evaluating case-vignettes of suspected SSI, considerable disagreement occurred regarding the diagnosis, with variations across specialties and countries.

Birgand, Gabriel; Lepelletier, Didier; Baron, Gabriel; Barrett, Steve; Breier, Ann-Christin; Buke, Cagri; Markovic-Denic, Ljiljana; Gastmeier, Petra; Kluytmans, Jan; Lyytikainen, Outi; Sheridan, Elizabeth; Szilagyi, Emese; Tacconelli, Evelina; Troillet, Nicolas; Ravaud, Philippe; Lucet, Jean-Christophe

2013-01-01

200

Florid lobular intraepithelial neoplasia with signet ring cells, central necrosis and calcifications: a clinicopathological and immunohistochemical analysis of ten cases associated with invasive lobular carcinoma.  

UK PubMed Central (United Kingdom)

BACKGROUND AND AIMS: In its most florid form, classic lobular intraepithelial neoplasia (LIN) proliferates to form a solid mass of tumor cells that fill and expand the duct within the terminal duct lobular unit lumen. Foci such as these can develop central necrosis and calcifications, detectable on mammograms. The immunohistochemical expression of E-cadherin has been found to be absent in all reported examples of LIN with necrosis. The occurrence of LIN composed entirely of signet ring cells with central necrosis is extraordinarily rare. METHODS: We described 10 of these cases to illustrate this uncommon morphologic pattern of LIN. The cases were encountered during routine clinical practice of the authors over a 5-year period at the Oncology Hospital of the Mexican Social Security Institute in Mexico City. Cases were comprised of several (>6) foci of LIN with signet ring cells as well as with comedo-type necrosis. RESULTS: Age of patients ranged from 45-75 years (mean age: 51.2 years). The indications for biopsy were calcifications (n = 7) and mass (n = 3) on mammograms. Luminal necrosis was seen in all ten cases and calcifications in seven cases. Eight cases had associated invasive carcinoma, including six lobular carcinomas and one composite carcinoma (lobular and ductal). All cases showed a lack of E-cadherin membrane staining and a diffuse cytoplasmic immunoreactivity for high molecular weight keratin, positivity for estrogen receptors and progesterone receptors was present in 9/10 and 8/10 of cases, respectively. CONCLUSIONS: LIN composed entirely of signet ring cells can develop macro-acini, central necrosis and calcifications. These cases are frequently associated with invasive lobular carcinoma at the time of initial presentation.

Alvarado-Cabrero I; Picón Coronel G; Valencia Cedillo R; Canedo N; Tavassoli FA

2010-08-01

 
 
 
 
201

Severe Allergic Reactions to Food in Norway: A Ten Year Survey of Cases Reported to the Food Allergy Register  

Directory of Open Access Journals (Sweden)

Full Text Available The Norwegian Food Allergy Register was established at the Norwegian Institute of Public Health in 2000. The purpose of the register is to gain information about severe allergic reactions to food in Norway and to survey food products in relation to allergen labelling and contamination. Cases are reported on a voluntary basis by first line doctors, and submitted together with a serum sample for specific IgE analysis. The register has received a total of 877 reports from 1 July, 2000 to 31 December, 2010. Two age groups, small children and young adults are over-represented, and the overall gender distribution is 40:60 males-females. The legumes lupine and fenugreek have been identified as two “new” allergens in processed foods and cases of contamination and faults in production of processed foods have been revealed. The highest frequency of food specific IgE is to hazelnuts and peanuts, with a marked increase in reactions to hazelnuts during the last three years. The Food Allergy Register has improved our knowledge about causes and severity of food allergic reactions in Norway. The results show the usefulness of population based national food allergy registers in providing information for health authorities and to secure safe food for individuals with food allergies.

Ellen Namork; Christiane K. Fæste; Berit A. Stensby; Eliann Egaas; Martinus Løvik

2011-01-01

202

Severe allergic reactions to food in Norway: a ten year survey of cases reported to the food allergy register.  

Science.gov (United States)

The Norwegian Food Allergy Register was established at the Norwegian Institute of Public Health in 2000. The purpose of the register is to gain information about severe allergic reactions to food in Norway and to survey food products in relation to allergen labelling and contamination. Cases are reported on a voluntary basis by first line doctors, and submitted together with a serum sample for specific IgE analysis. The register has received a total of 877 reports from 1 July, 2000 to 31 December, 2010. Two age groups, small children and young adults are over-represented, and the overall gender distribution is 40:60 males-females. The legumes lupine and fenugreek have been identified as two "new" allergens in processed foods and cases of contamination and faults in production of processed foods have been revealed. The highest frequency of food specific IgE is to hazelnuts and peanuts, with a marked increase in reactions to hazelnuts during the last three years. The Food Allergy Register has improved our knowledge about causes and severity of food allergic reactions in Norway. The results show the usefulness of population based national food allergy registers in providing information for health authorities and to secure safe food for individuals with food allergies. PMID:21909296

Namork, Ellen; Fæste, Christiane K; Stensby, Berit A; Egaas, Eliann; Løvik, Martinus

2011-07-26

203

Trends in the theoretical and research methodological approaches applied in doctoral studies in information and knowledge management: an exploration of ten years of research in South Africa  

Directory of Open Access Journals (Sweden)

Full Text Available The past ten years have seen the field of information and knowledge management develop and implement new and improved technologies. Because of the ease with which information is exchanged the contribution to information overload has increased exponentially and the need for information and knowledge management is more real than ever before. Research in itself is a science of knowledge creation that continuously evolves in line with newly developed theories and research methodologies. An investigation of the theories and research methodologies that doctoral theses, completed in South Africa, ascribed to over the past ten years were conducted. Search strings containing 'information management', 'knowledge management' and 'information and knowledge management' were searched within citation, abstract and subject fields. A sample of 30 theses from a possible 47 in the relevant population was identified. Qualitative and mixed methods research design was favoured, making use of case studies and surveys, but paying little attention to theoretical approaches or paradigms. The boundaries between disciplines are continuously re-defined, new disciplines evolve and traditional disciplines suffer under the pressures of changing problems of the world. The importance of research in the field of information and knowledge management being grounded in the most recent scientific thought is emphasized.

M. A. Mearns

2010-01-01

204

Trends in the theoretical and research methodological approaches applied in doctoral studies in information and knowledge management: an exploration of ten years of research in South Africa  

Directory of Open Access Journals (Sweden)

Full Text Available The past ten years have seen the field of information and knowledge management develop and implement new and improved technologies. Because of the ease with which information is exchanged the contribution to information overload has increased exponentially and the need for information and knowledge management is more real than ever before. Research in itself is a science of knowledge creation that continuously evolves in line with newly developed theories and research methodologies. An investigation of the theories and research methodologies that doctoral theses, completed in South Africa, ascribed to over the past ten years were conducted. Search strings containing 'information management', 'knowledge management' and 'information and knowledge management' were searched within citation, abstract and subject fields. A sample of 30 theses from a possible 47 in the relevant population was identified. Qualitative and mixed methods research design was favoured, making use of case studies and surveys, but paying little attention to theoretical approaches or paradigms. The boundaries between disciplines are continuously re-defined, new disciplines evolve and traditional disciplines suffer under the pressures of changing problems of the world. The importance of research in the field of information and knowledge management being grounded in the most recent scientific thought is emphasized.

M. A. Mearns

2008-01-01

205

Effectiveness of non-adjuvanted monovalent A(H1N1)pdm09 vaccines for preventing RT-PCR-confirmed pandemic influenza hospitalizations: Case-control study of children and adults at ten U.S. Influenza Surveillance Network sites.  

UK PubMed Central (United Kingdom)

During 2009-2010, we examined 217 cases hospitalized with laboratory-confirmed pandemic influenza in nine FluSurv-NET sites and 413 age- and community-matched controls and found a single dose of monovalent non-adjuvanted influenza A(H1N1)pdm09 vaccine was 50% (95% CI=13%-71%) effective in preventing hospitalization associated with A(H1N1)pdm09 virus infection.

Thompson M; Sokolow LZ; Almendares O; Openo K; Farley MM; Meek J; Ray J; Kirley PD; Reingold A; Aragon D; Hancock E; Baumbach J; Schaffner W; Lynfield R; Ryan P; Monroe M; Cheng PY; Fry A; Shay DK

2013-08-01

206

The applicability of Ki-67 marker for renal epithelioid angiomyolipoma: experience of ten cases from a single center.  

UK PubMed Central (United Kingdom)

In order to present our experience with 10 cases of renal epithelioid angiomyolipoma (EAML) and validate the applicability of Ki-67 (proliferation marker) for EAML, we reviewed medical records of 10 consecutive cases diagnosed EAML from January 2005 to February 2012 at our department. Clinical data were collected and analyzed and pathology slides were reviewed. The immunohistochemical reactions for Ki-67 were performed and tumors showed positive expression were estimated. Active follow-up was performed to investigate the association between Ki-67 expression and the prognosis. The mean age and tumor size of the patients was 43.6 years (range 32-56) and 8.2 cm (range 2-15 cm), respectively. Seven were females while three were males. Radical nephrectomy was performed in 6 patients, partial nephrectomy in 3, and renal artery ligation in 1. The immunohistochemical reactions for HMB-45 (Human Melanoma Black), SMA (Smooth Muscle Actin) were positive but for S-100 were negative. The number of patients showing positive/negative Ki-67 expression was 5/5. The survival rate of the positive group was 20% (1/5) while 100% (5/5) of the negative group during the median follow-up time of 26.75 months (range 1-53). Recurrence, metastasis and death due to disease occurred in 1 (10%), 3 (30%) and 4 (40%) patients, respectively. Higher expression (positive) of Ki-67 indicates the presence of EAML and poor prognosis of patients. Surgical excision including radical and partial nephrectomy is a considerable approach to the treatment for its malignant potential.

Xu C; Jiang XZ; Zhao HF; Zhang NZ; Ma L; Xu ZS

2013-01-01

207

PREDICT : A CASE STUDY.  

Energy Technology Data Exchange (ETDEWEB)

Delphi Automotive Systems and the Los Alamos National Laboratory worked together to develop PREDICT, a new methodology to characterize the reliability of a new product during its development program. Rather than conducting testing after hardware has been built, and developing statistical confidence bands around the results, this updating approach starts with an early reliability estimate characterized by large uncertainty, and then proceeds to reduce the uncertainty by folding in fresh information in a Bayesian framework. A considerable amount of knowledge is available at the beginning of a program in the form of expert judgment which helps to provide the initial estimate. This estimate is then continually updated as substantial and varied information becomes available during the course of the development program. This paper presents a case study of the application of PREDICT, with the objective of further describing the methodology. PREDICT has been honored with an R&D 100 Award presented by R&D Magazine.

Kerscher, W. J. (William J.) III; Booker, J. M. (Jane M.); Meyer, Mary A.

2001-01-01

208

Theoretical study on ten ?-S states of Si2- anion: Potential energy curves, spectroscopy and spin-orbit couplings  

Science.gov (United States)

The potential energy curves (PECs) of seventeen ? states generated from the ten ?-S states of the Si2- anion are studied in detail using an ab initio quantum chemical method for the first time. The PECs are calculated for internuclear separations from 0.10 to 1.20 nm by the complete active space self-consistent field method, which is followed by the internally contracted multireference configuration interaction approach with the Davidson modification. The spin-orbit coupling is accounted for by the Breit-Pauli Hamiltonian. Core-valence correlation and scalar relativistic corrections are considered. Core-valence correlation corrections are included using an aug-cc-pCVTZ basis set. Scalar relativistic correction calculations are made with the third-order Douglas-Kroll Hamiltonian approximation at the level of a cc-pV5Z basis set. Obvious effect of core-valence correlation corrections on the PECs is observed, in particular for the two lowest 2?u and 2?g+ ?-S states. All the PECs are extrapolated to the complete basis set limit. The lowest 2?u ?-S state is found to be the ground state of Si2- anion. The convergence observations of present calculations are made and the convergent behavior is discussed with respect to the basis set and level of theory. The effects of core-electron correlations on the energy splitting are studied by the all-electron aug-cc-pCVTZ basis set. Using these PECs, the spectroscopic parameters of ?-S and ? states involved are determined. The vibrational manifolds are evaluated for each ?-S and ? state of non-rotation Si2- anion. It shows that the spectroscopic parameters and molecular constants of ten ?-S and seventeen ? states reported here can be expected to be reliable predicted ones.

Liu, Hui; Shi, Deheng; Sun, Jinfeng; Zhu, Zunlue

2013-05-01

209

FMCT verification: Case studies  

International Nuclear Information System (INIS)

Full text: How to manage the trade-off between the need for transparency and the concern about the disclosure of sensitive information would be a key issue during the negotiations of FMCT verification provision. This paper will explore the general concerns on FMCT verification; and demonstrate what verification measures might be applied to those reprocessing and enrichment plants. A primary goal of an FMCT will be to have the five declared nuclear weapon states and the three that operate unsafeguarded nuclear facilities become parties. One focus in negotiating the FMCT will be verification. Appropriate verification measures should be applied in each case. Most importantly, FMCT verification would focus, in the first instance, on these states' fissile material production facilities. After the FMCT enters into force, all these facilities should be declared. Some would continue operating to produce civil nuclear power or to produce fissile material for non- explosive military uses. The verification measures necessary for these operating facilities would be essentially IAEA safeguards, as currently being applied to non-nuclear weapon states under the NPT. However, some production facilities would be declared and shut down. Thus, one important task of the FMCT verifications will be to confirm the status of these closed facilities. As case studies, this paper will focus on the verification of those shutdown facilities. The FMCT verification system for former military facilities would have to differ in some ways from traditional IAEA safeguards. For example, there could be concerns about the potential loss of sensitive information at these facilities or at collocated facilities. Eventually, some safeguards measures such as environmental sampling might be seen as too intrusive. Thus, effective but less intrusive verification measures may be needed. Some sensitive nuclear facilities would be subject for the first time to international inspections, which could raise concerns for states that have traditionally had 'less transparency' in their military sectors. As case studies, first we investigate how to applied verification measures including remote sensing, off-site environmental sampling and on-site inspections to monitor the shutdown status of plutonium production facilities, and what measures could be taken to prevent the disclosure of sensitive information at the site. We find the most effective verification measure to monitor the status of the reprocessing plant would be on-site environmental sampling. Some countries may worry that sample analysis could disclose sensitive information about their past plutonium production activities. However, we find that sample analysis at the reprocessing site need not reveal such information. Sampling would not reveal such information as long as inspectors are not able to measure total quantities of Cs-137 and Sr-90 from HLW produced at former military plutonium production facilities. Secondly, we consider verification measures for shutdown gaseous diffusion uranium-enrichment plants (GDPs). The GDPs could be monitored effectively by satellite imagery, as one telltale operational signature of the GDP would be the water-vapor plume coming from the cooling tower, which should be easy to detect with satellite images. Furthermore, the hot roof of the enrichment building could be detectable using satellite thermal-infrared images. Finally, some on-site verification measures should be allowed, such as visual observation, surveillance and tamper-indicating seals. Finally, FMCT verification regime would have to be designed to detect undeclared fissile material production activities and facilities. These verification measures could include something like special or challenge inspections or complementary access. There would need to be provisions to prevent the abuse of such inspections, especially at sensitive and non-proscribed military and nuclear activities. In particular, to protect sensitive information, it is essential to have an appropriate managed access mechanism, which should be able to re

2001-11-02

210

Endovascular treatment of false-aneurysm ten years after dacron patch aortoplasty for coarctation of the aortic isthmus Report of a case.  

UK PubMed Central (United Kingdom)

UNLABELLED: False aneurysm degeneration is a known complication of patch aortoplasty for coarctation of the aortic isthmus. Open surgical treatment consists of prosthetic graft repair of the involved aorta, often requires circulatory arrest to achieve a safe proximal aortic control and perform proximal anastomosis, and finally is associated with substantial perioperative morbidity. Endografting of the diseased aorta is a valuable alternative to open repair, when feasible, with good short and long term results. We now report one more case of false aneurysm ten years after Dacron patch aortoplasty for isthmic coarctation in a 26-year-old woman, successfully treated by endovascular repair via the left common iliac artery, and a complete exclusion of the aneurysm at two year follow-up. KEY WORDS: Aortic coarctation, Endovascular treatment, False aneurysm.

Illuminati G; Pacilè MA; Palumbo P; Salvatori FM; Vietri F

2013-01-01

211

Stroke in the postpartum period: a case study.  

UK PubMed Central (United Kingdom)

A twenty six years old woman presented with visual disturbance, headache and gait disturbance ten weeks postpartum. Imaging studies identified an acute infarction in the left thalamus. This case report discusses her presentation, investigations and management and the aetiology of stroke in pregnancy and the postpartum period.

Sj A; A B; Hussein OM; Ra A

2013-06-01

212

Experimental Study of the Dynamic Response of a Ten-Story Reinforced Concrete Frame with a Tall First Story.  

Science.gov (United States)

This report documents the experimental work and presents the response data obtained in three earthquake simulation tests of a ten-story reinforced concrete frame. Changes in the dynamic properties of the test structure, such as apparent frequencies and eq...

M. A. Sozen T. J. Healey

1978-01-01

213

Ten years of progress in the Hokkaido birth cohort study on environment and children's health: cohort profile-updated 2013.  

UK PubMed Central (United Kingdom)

The Hokkaido Study on Environment and Children's Health is an ongoing cohort study that began in 2002. The study consists of two prospective birth cohorts, the Sapporo cohort (n = 514) and the Hokkaido large-scale cohort (n = 20,940). The primary goals of this study are to first examine the potential negative effects of perinatal environmental chemical exposures on birth outcomes, including congenital malformations and growth retardation; second, to evaluate the development of allergies, infectious diseases and neurodevelopmental disorders and perform longitudinal observations of the children's physical development to clarify the causal relationship between these outcomes and environmental chemicals; third, to identify individuals genetically susceptible to environmental chemicals; finally, to identify the additive effects of various environmental factors in our daily life, such as secondhand smoke exposure or low folate intake during early pregnancy. In this paper, we introduce our recent progress in the Hokkaido study with a cohort profile updated in 2013. For the last ten years, we followed pregnant women and their offspring, measuring various environmental chemicals, i.e., PCB, OH-PCB and dioxins, PFCs (Perfluorinated Compounds), Organochlorine pesticides, Phthalates, bisphenol A and mercury. We discovered that the concentration of toxic equivalents (TEQ) of dioxin and other specific congeners of PCDF or PCDD have effects on birth weight, infants' neurodevelopment and immune function. There were significant gender differences in these effects; our results suggest that male infants have more susceptibility to those chemical exposures than female infants. Interestingly, we found maternal genetic polymorphisms in AHR, CYP1A1 or GSTs that significantly modified the dioxin concentrations in maternal blood, suggesting different dioxin accumulations in the bodies of individuals with these genotypes, which would lead to different dioxin exposure levels. These genetic susceptibility factors influenced the body size of children born from mothers that either smoked or were passively exposed to tobacco smoke. Further studies investigating the correlation between epigenetics, the effects of intrauterine exposure to environmental chemicals and developmental factors related to health and disease are warranted.

Kishi R; Kobayashi S; Ikeno T; Araki A; Miyashita C; Itoh S; Sasaki S; Okada E; Kobayashi S; Kashino I; Itoh K; Nakajima S

2013-08-01

214

Regroup Ones as Tens  

Science.gov (United States)

This quick slide show demonstrates for students how to use base ten blocks to regroup, trade, or change groups of 1's into 10's. When you have more than 10 ones base ten blocks, students should regroup or change, 10 ones to 1 ten. User clicks through the slides.

Eduplace.com

2011-06-28

215

Effects of reflexology on fibromyalgia symptoms: a multiple case study.  

UK PubMed Central (United Kingdom)

PURPOSE: To explore the effects of reflexology on pain and other symptoms in women with fibromyalgia syndrome [FM]. METHODS: Multiple case study method as developed by Stake was used to investigate the effects of reflexology on six cases of women with FM which were given ten sessions of weekly reflexology. Data were collected with observation, interviews and diary and then analyzed within cases and across cases. RESULTS: Reflexology affected the symptom of pain in multiple areas such as head, neck and arms. Pain started to isolate and decrease. CONCLUSION: Reflexology may be helpful to decrease fibromyalgia symptoms. Qualitative research methods and individually tailored interventions are important when researching complementary and alternative therapies.

Gunnarsdottir TJ; Peden-McAlpine C

2010-08-01

216

The Bureaucratization, Commodification, and Privatization of Sexual Harassment through Institutional Discourse: A Study of the Big Ten Universities.  

Science.gov (United States)

Addresses how universities frame their managerial discourse regarding sexual harassment, which often perpetuates the bureaucratization, commodification, and privatization of sexual harassment. Offers a poststructuralist critique and deconstruction of the policies and brochures developed by the Big Ten universities to reveal oppressive and/or…

Clair, Robin P.

1993-01-01

217

A comparative study of transcutaneous electrical nerve stimulation (TENS), entonox, pethidine + promazine and lumbar epidural for pain relief in labor.  

UK PubMed Central (United Kingdom)

Analgesic effect, labor outcome, safety and consumer satisfaction were compared in 170 primigravid women; 50 using TENS initially for pain relief, 20 using entonox, 50 pethidine + promazine and 50 lumbar epidural. 88% choosing epidural related it fully effective. 90% using entonox, 96% using TENS and 54% given pethidine + promazine found partial relief. 82% of patients given TENS and 80% given pethidine + promazine required additional analgesia. This was also needed by one of the 20 patients choosing entonox. Women using entonox alone had the shortest labors and women using lumbar epidural, the longest. Operative delivery was significantly more common in women receiving lumbar epidural. No significant inter-group differences were noted in cord pH or Apgar scores. Parturients and midwives both gave high consumer satisfaction ratings to all methods--except for pethidine + promazine, whose use must therefore be questioned. The analgesic efficacy of lumbar epidural outweighs any possible side effects. Entonox appears suited to those able to cope with the earlier part of labor, drug-free. Realization of the potential of TENS requires the design of machines specifically to cope with the quality of the pain of labor.

Harrison RF; Shore M; Woods T; Mathews G; Gardiner J; Unwin A

1987-01-01

218

Effects of TENS and methylphenidate in tuberculous meningo-encephalitis.  

UK PubMed Central (United Kingdom)

PRIMARY OBJECTIVE: Beneficial effects of transcutaneous electrical nerve stimulation (TENS) on cognition and behaviour were observed in a child with probable Herpes Simplex Encephalitis. Based on these positive findings, it was examined in the present case study whether a child who had been diagnosed to suffer from tuberculous meningitis would benefit from TENS. Furthermore, as aggression and overactive behaviour were also prominent clinical symptoms, the effects of methylphenidate were investigated. METHODS AND PROCEDURES: Neuropsychological tests were used to assess attention/concentration and visuospatial and visuoconstructive memory. Behaviour, including the level of activity during 24 hours, was assessed by one observation scale and actigraphy. EXPERIMENTAL INTERVENTIONS: TENS and methylphenidate. MAIN OUTCOMES AND RESULTS: TENS particularly improved overall affective behaviour. Methylphenidate appeared to have the opposite effect on cognition and hardly any effect on patient's behaviour. CONCLUSIONS: TENS might improve the patient's behavioural functioning. Pros and cons for treatment effects are discussed.

Scherder EJ; Van Deursen S; Van Manen SR; Ferenschild K; Simis R; Vuyk PJ

2001-06-01

219

Case study Netherlands: Reference case II  

Energy Technology Data Exchange (ETDEWEB)

Recent case studies carried out with the sectoral part of the medium term EC energy demand model for the Netherlands are described. The hypotheses used for the macroeconomic model for the Netherlands are presented. These hypotheses have been agreed by national experts. The results of two different simulations which demonstrate the reaction of energy demand to different energy prices and different macroeconomic developments are given. In the second part of the report, the results are compared with those from national forecasts performed at about the same time by the Central Planning Bureau at The Hague. Conclusions are drawn as to the plausibility of results.

Valette, P.; Heuvel, P. van den

1984-01-01

220

Theory testing using case studies  

DEFF Research Database (Denmark)

Case studies may have different research goals. One such goal is the testing of small-scale and middle-range theories. Theory testing refers to the critical examination, observation, and evaluation of the 'why' and 'how' of a specified phenomenon in a particular setting. In this paper, we focus on the strengths of theory-testing case studies. We specify research paths associated with theory testing in case studies and present a coherent argument for the logic of theoretical development and refinement using case studies. We emphasize different uses of rival explanations and their implications for research design. Finally, we discuss the epistemological logic, i.e., the value to larger research programmes, of such studies and, following Lakatos, conclude that the value of theory-testing case studies lies beyond naïve falsification and in their contribution to developing research programmes in a progressive way.

Dissing SØrensen, Pernille; LØkke Nielsen, Ann-Kristina

 
 
 
 
221

Incidence of glaucomatous visual field loss: a ten-year follow-up from the Rotterdam Study.  

UK PubMed Central (United Kingdom)

PURPOSE: To determine the 10-year incidence of glaucomatous visual field loss (GVFL) and to investigate the influence of risk factors for open-angle glaucoma on this incidence. DESIGN: Population-based cohort study. PARTICIPANTS: Participants aged > or =55 years from the Rotterdam Study. METHODS: Of the 7983 participants in the Rotterdam Study, 6806 underwent ophthalmic examinations at baseline (1990-1993). In 6723 of these 6806 participants (99%), both visual field screening and an assessment of the optic disc were performed. After exclusion of 93 participants with GVFL at baseline, 6630 participants at risk of developing GVFL remained. These participants underwent similar ophthalmic examinations during 2 follow-up visits (1997-1999 and 2002-2006). The incidence of GVFL was determined as an incidence rate and recalculated to a 10-year risk. Risk factors for open-angle glaucoma (age, gender, positive family history of glaucoma, baseline intraocular pressure (IOP), myopia, and baseline vertical cup-to-disc ratio [VCDR]) were assessed using Cox regression. The dependent variable was the development of GVFL. MAIN OUTCOME MEASURES: Ten-year risk and incidence rates of GVFL. Hazard ratios of the above-mentioned risk factors. RESULTS: Of 6630 participants, 3939 (59%) completed at least 1 follow-up examination and 2571 (39%) completed both; 108 participants developed GVFL. The overall incidence rate and 10-year risk of GVFL were 2.9 per 1000 person-years (95% confidence interval [CI], 2.4-3.5) and 2.8% (2.3-3.4), respectively. The 10-year risk increased from 1.9% at age 55 to 59 years to 6.4% at age > or =80 years (P<0.001). The incidence increased by 11% per millimeter of mercury increase in IOP (hazard ratio 1.11; 95% CI, 1.06-1.15). Male gender (1.62; 1.10-2.38), high myopia (spherical equivalent < or =-4 D myopic; 2.31; 1.19-4.49), and a baseline VCDR above the 97.5th percentile (4.64; 2.72-7.91) were associated with the development of GVFL. A positive family history was only significantly associated with the development of GVFL if IOP was removed from the model (2.0; 1.2-3.3; P = 0.012). CONCLUSIONS: These data provide an estimate of the incidence of GVFL in a white population. The development of GVFL was related to higher IOP, older age, high myopia, male gender, a positive family history of glaucoma, and a larger baseline VCDR.

Czudowska MA; Ramdas WD; Wolfs RC; Hofman A; De Jong PT; Vingerling JR; Jansonius NM

2010-09-01

222

Innovation for Sustainable Tourism : International Case Studies  

DEFF Research Database (Denmark)

Innovation is the key to responding to the future challenges that confront all sectors of society and the economy, and especially in tourism. Within tourism, there are numerous corporations and destinations around the world that are responding to the ecological, social and economic challenges and making the transformation toward sustainability through innovation. This book assembles ten case studies of large and small enterprises and destinations in developed and developing nations that are pursuing innovative practices that will enhance the sustainability of their operations. The chapters in this volume are based on primary and secondary research by the contributing authors and each chapter has been peer reviewed prior to publication. Cross-case analysis (Patton 1990) was also used to provide a framework for comparing and contrasting the different types and contexts of innovation and provide for an integrated overview of the drivers, barriers, processes and networks for innovation. The cases have been prepared for use in research and teaching of innovation, and the analysis and case notes are both designed to facilitate discussion and further investigation of innovation, not only in tourism, but in other economic sectors as well. Being an online publication, it is expected that updates in successive editions of this first book will add further to the description and analysis of innovation for sustainable tourism and hence provide a resource for those seeking to enhance the teaching, research and practice of innovation.

Carlsen, Jack

2007-01-01

223

A TEN YEAR STUDY OF THE MANAGEMENT OF HAEMORRHOIDS AT A SECONDARY NURSING HOME IN SOUTH WEST NIGERIA  

Directory of Open Access Journals (Sweden)

Full Text Available This retrospective study evaluated the different treatment options used in the management of haemorrhoids in a state government owned secondary hospital, Jericho Nursing Home, Ibadan, Nigeria. The study was conducted for a period of two weeks covering June 5th – 17th 2007.The total of 120 case notes available for patients treated for haemorrhoids were used and thoroughly studied. The case notes consist of Thirty four (28.3%) males and 86 (71.7%) females who were aged between 21-40 years 57(47.5%), between 41-60 years 41(34.2%) and between 61-80years 22(18.3%).Among the nursing mothers whose case notes were studied, 57(47.5%) were pregnant while 63(52.5%) were not pregnant.The nursing mothers’ occupations were marketing 4(3.3%), trading 36(30.0%), secretary 14(11.7%), teaching 16(13.3%), accounting 3(2.5%), student 7(5.8%), civil servant 6(5.0%), engineering 9(7.5%) and retirees 8(6.7%) with 17(14.2%) not indicating their occupation.Treatment options reviewed showed that those treated with sitzbath were 58(20.7%), with oral liquid paraffin they were 62(22.1%), with Anusol suppositories they were 48(17.1%), with dietary advice they were 87(31.2%), with Surgery (haemorrhoidectomy) they were 3(1.1%) and with TCP ointment/Xylocaine gel they were 22(7.9%).Statistical analysis was done using the SPSS version 11.0 software programmer for frequency and cross tabulation.There is a need to improve on these treatment options. More innovative methods should be developed for effective treatment of haemorrhoids.

Omole Moses Kayode; Adegboye Oyebukola O.

2012-01-01

224

Roundabouts Canada case study  

Energy Technology Data Exchange (ETDEWEB)

A modern roundabout was constructed in the community of Ancaster, Ontario in response to growing complaints regarding speeding along the major roadway, and queuing on the minor roadway. The roundabout opened on October 25, 2002. The before and after speeds at the roundabout are being studied, and the fastest path characteristics are assessed in an effort to determine whether the predicted fastest path data correlates with the in-service operating speeds. The speed at R1, R2 and R3 locations on the east west, and north south approaches are measured. tabs., figs.

Jamieson, M. [Ryerson Polytechnic Univ., Toronto, ON (Canada); Lenters, M. [Roundabouts Canada, Whitby, ON (Canada)

2002-07-01

225

Geostatistical case studies  

Energy Technology Data Exchange (ETDEWEB)

The objective of this volume of contributed chapters is to present a series of applications of geostatistics. These range from a careful variographic analysis on uranium data, through detailed studies on geologically complex deposits, right up to the latest nonlinear methods applied to deposits with highly skewed data contributions. Applications of new techniques such as the external drift method for combining well data with seismic information have also been included. The volume emphasizes geostatistics in practice. Notation has been kept to a minimum and mathematical details have been relegated to annexes.

Matheron, G.; Armstrong, M.

1987-01-01

226

Implementing sustainable forest management: some case studies  

Energy Technology Data Exchange (ETDEWEB)

Case studies are presented to illustrate the variability surrounding the change from the traditional fibre-production under sustained-yield management approach to a broader strategy of sustainable management of all forest values. Examples selected and discussed in detail include: (1) the Lac Duparquet Research and Teaching Forest, which is an example of forest management where research and natural disturbance-based management are fully balanced, (2) the Alberta-Pacific Forest Industries Woodlands Management Program, also based on natural disturbances, (3) the Louisiana-Pacific Canada's Swan Valley Forest Resources Division Agreement, a ten-year development plan to achieve sustainable management in an adaptive management context, (4) the Bas-Saint-Laurent Model Forest, committed to sustainable forest management program, with the additional objective of achieving sustainability and economic development in a forest tenant farming environment, and (5) Mistik Management Ltd, a forest management company in Saskatchewan that has made a strong commitment over the past 10 years to local involvement in forestry planning and operations, active multiple resource management, and adaptive forest management principles. In-depth analysis and detailed description of the management principles underlying the operations in each of the five cases are provided. The case studies illustrate the wide variety of options available for conserving biodiversity and highlight the difficulties involved in attaining a broad set of forest values, including wild life, habitat, rural lifestyles, community stability, corporate and provincial revenue objectives. 81 refs., 7 figs.

Hebert, D. [Encompass Strategic Resources Inc., Creston, BC (Canada); Harvey, B. [Universite du Quebec en Abitibi-Temiscamingue, Rouyn-Noranda, PQ (Canada); Wasel, S.; Dzus, E. H. [Alberta-Pacific Forest Industries Inc., Boyle, AB (Canada); Donnelly, M. [Louisiana-Pacific Canada Ltd., Swan River, MB (Canada); Robert, J. [Service canadien des forets, Programme des forets modeles, Rimouski, PQ (Canada); Chambers, F. H. [Victoria Univ., School of Environmental Studies, Victoria, BC (Canada)

2003-07-01

227

Cervical neoplasia case studies  

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Full Text Available Cancer is nowadays one of the most important health problems. In Romania cancer is the second in generalmorbidity after cardio-vascular diseases, being followed by respiratory diseases, accidents and trauma. Considering thefact that cancer has an insidious start, a slow irreversible development towards physical and psychic invalidity, and that it affects both the person and the family and society, we can say it is very important to have a study of this illness from thesocial and medical point of view. The cytological examination offers, apart from the highlighting of the tumour cells, thepossibility of assessing the hormonal status, and also of identifying vaginal flora. Cervical cancer is a serious chroniccondition, which has great medical and social importance and has a severe evolution when detected in advanced stages.

Eduard Crauciuc; Ovidiu Toma; Doina Iancu; Dragos Crauciuc

2012-01-01

228

Cervical neoplasia case studies  

Directory of Open Access Journals (Sweden)

Full Text Available Cancer is nowadays one of the most important health problems. In Romania cancer is the second in generalmorbidity after cardio-vascular diseases, being followed by respiratory diseases, accidents and trauma. Considering thefact that cancer has an insidious start, a slow irreversible development towards physical and psychic invalidity, and that it affects both the person and the family and society, we can say it is very important to have a study of this illness from thesocial and medical point of view. The cytological examination offers, apart from the highlighting of the tumour cells, thepossibility of assessing the hormonal status, and also of identifying vaginal flora. Cervical cancer is a serious chroniccondition, which has great medical and social importance and has a severe evolution when detected in advanced stages.

Eduard Crauciuc; Ovidiu Toma; Doina Iancu; Dragos Crauciuc

2013-01-01

229

Sternocleidomastoid syndrome: a case study  

Digital Repository Infrastructure Vision for European Research (DRIVER)

This article presents a case study of a patient diagnosed with dysfunction of the sternocleidomastoid (SCM) muscle, a condition which can result in head and face pain, nausea, dizziness, coryza, and lacrimation. In this particular case, the SCM muscle had developed tightness and weakness with presen...

Missaghi, Babak

230

Effects of tripolar TENS of vertebral column on slow and fast motor units: A preliminary study using H-reflex recovery curve method  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Introduction: Effect of tripolar TENS of vertebral column on slow and fast motoneurons (MNs) activity of soleus muscle was previously investigated. In this study for better differentiation of the behavior of slow and fast MNs, we exploited H-reflex recovery curve recording in two muscles of soleus a...

Leila Simorgh; Giti Torkaman; Seyyed Mohammad Firoozabadi

231

The effect of manganese on the central nervous system. On the basis of ten cases with hyperintensities in the globus pallidus and a part of the brainstem on T1-weighted magnetic resonance imaging  

International Nuclear Information System (INIS)

We examined the effect of manganese (Mn) on the central nervous system, on the basis of ten cases with hyperintensities in the globus pallidus and a part of the brainstem on T1-weighted magnetic resonance imaging (MRI). These cases were divided into three groups; four cases with liver dysfunction, three cases with intravenous infusion containing Mn and three cases without any specific factor. Mn levels were measured in serum, whole blood and cerebrospinal fluid (CSF). As a result, their serum and CSF Mn levels were significantly higher (P

1998-01-01

232

ICT PROJECTS - Case Study Reports  

Digital Repository Infrastructure Vision for European Research (DRIVER)

The case study of OVK (Seamless healthcare chain supported by ICT (Obruten vårdkedja med IT –stöd) describes some basic key factors for sucessful eHealth project, and is documented in the projects database in IANIS+

Bai, Guohua

233

Case Studies in Library Security  

CERN Document Server

This book employs a familiar vehicle in library literature—the case study—but in a departure from the expected, takes that time-honored genre into a new dimension. Shuman uses the conversational narrative as a vehicle for portraying 40 security and safety issues that may arise in libraries, disturbing or vexing patrons and library staff members, alike. Unlike the traditional narrative approach of other case study books, in this work, each case is presented as a soliloquy, within a fictional but plausible library situation, whereby the protagonist uses his or her own colorful mode of expression

Shuman, Bruce A

2002-01-01

234

Malformación de Chiari tipo I: evolución postoperatoria a dos años. Análisis de 10 casos/ Chiari I malformation: postsurgical evolution after 2 years: Report of ten cases  

Scientific Electronic Library Online (English)

Full Text Available Abstract in spanish Objetivo. Describir la evolución de 10 pacientes con Malformación de Chiari tipo I (MCI), desde el punto de vista clínico y de imagen mediante resonancia magnética (RM). Método. A 10 pacientes con Malformación de Chiari se les realizó craniectomía suboccipital media, resección de arco posterior de C1 y plastia dural. A todos se les hizo un seguimiento clínico de dos años, y se hizo evaluación mediante RM a los seis meses del postoperatorio. Se correlaciona el (more) tiempo de evolución preoperatoria, hallazgos de imagen mediante RM y la evolución clínica postoperatoria. Resultados. La evolución clínica postoperatoria mostró una mejoría importante en cuanto a función sensitiva, correlacionándose con la involución de la siringohidromielia que acompañaba a esos casos, mejoría parcial de sus funciones cerebelosas y, en menor grado, mejoría de la alteración motora. Las manifestaciones de atrofia muscular no tuvieron modificaciones en el seguimiento a dos años. Conclusiones. La MCI es una enfermedad congénita con múltiples manifestaciones clínicas que se van agravando conforme pasa el tiempo. Un diagnóstico oportuno y un tratamiento adecuado son indispensables para obtener los mejores resultado posibles desde el punto de vista neurológico. Abstract in english Objective To describe the clinical and radiological evolution of ten patients with Chiari I malformation (CIM), treated surgically. Method. Ten patients with Chiari I malformation underwent suboccipital craniectomy, laminectomy of C1 and dural patch grafting. All of them were followed for at least two years. A magnetic resonance imaging was performed 6 months after surgery. Clinical preoperative evolution and time of installation, results of MRI and clinical postoperative (more) evolution were correlated. Results. In postoperative clinical evolution, we noted an important improvement in sensitive function, decrease of the syringohydromielia and partial improvement of cerebellar functions. Improvement of the motor alteration was less marked. During the two years after treatment the muscular atrophy did not change. Conclusions. Chiari I malformation is a congenital disease with many clinical manifestations which usually increase with time. A suitable diagnostic studies as well as an appropriate treatment are needed to improve the neurological results.

Alvarez-Betancourt, L.; García-Rentaría, J. A.; López-Ortega, S.J.; Caldera-Duarte, A.

2005-02-01

235

Malformación de Chiari tipo I: evolución postoperatoria a dos años. Análisis de 10 casos Chiari I malformation: postsurgical evolution after 2 years: Report of ten cases  

Directory of Open Access Journals (Sweden)

Full Text Available Objetivo. Describir la evolución de 10 pacientes con Malformación de Chiari tipo I (MCI), desde el punto de vista clínico y de imagen mediante resonancia magnética (RM). Método. A 10 pacientes con Malformación de Chiari se les realizó craniectomía suboccipital media, resección de arco posterior de C1 y plastia dural. A todos se les hizo un seguimiento clínico de dos años, y se hizo evaluación mediante RM a los seis meses del postoperatorio. Se correlaciona el tiempo de evolución preoperatoria, hallazgos de imagen mediante RM y la evolución clínica postoperatoria. Resultados. La evolución clínica postoperatoria mostró una mejoría importante en cuanto a función sensitiva, correlacionándose con la involución de la siringohidromielia que acompañaba a esos casos, mejoría parcial de sus funciones cerebelosas y, en menor grado, mejoría de la alteración motora. Las manifestaciones de atrofia muscular no tuvieron modificaciones en el seguimiento a dos años. Conclusiones. La MCI es una enfermedad congénita con múltiples manifestaciones clínicas que se van agravando conforme pasa el tiempo. Un diagnóstico oportuno y un tratamiento adecuado son indispensables para obtener los mejores resultado posibles desde el punto de vista neurológico.Objective To describe the clinical and radiological evolution of ten patients with Chiari I malformation (CIM), treated surgically. Method. Ten patients with Chiari I malformation underwent suboccipital craniectomy, laminectomy of C1 and dural patch grafting. All of them were followed for at least two years. A magnetic resonance imaging was performed 6 months after surgery. Clinical preoperative evolution and time of installation, results of MRI and clinical postoperative evolution were correlated. Results. In postoperative clinical evolution, we noted an important improvement in sensitive function, decrease of the syringohydromielia and partial improvement of cerebellar functions. Improvement of the motor alteration was less marked. During the two years after treatment the muscular atrophy did not change. Conclusions. Chiari I malformation is a congenital disease with many clinical manifestations which usually increase with time. A suitable diagnostic studies as well as an appropriate treatment are needed to improve the neurological results.

L. Alvarez-Betancourt; J. A. García-Rentaría; S.J. López-Ortega; A. Caldera-Duarte

2005-01-01

236

Incidence of cancer in children residing in ten jurisdictions of the Mexican Republic: importance of the Cancer registry (a population-based study)  

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Full Text Available Abstract Background In 1996, Mexico started to register cases of childhood cancer. Here, we describe the incidence of cancer in children, residing in ten Mexican jurisdictions, who were treated by the Instituto Mexicano del Seguro Social (IMSS). Methods New cases of childhood cancer, which were registered prospectively in nine principal Medical Centers of IMSS during the periods 1998–2000 (five jurisdictions) and 1996–2002 (five jurisdictions), were analyzed. Personnel were specifically trained to register, capture, and encode information. For each of these jurisdictions, the frequency, average annual age-standardized incidence (AAS) and average annual incidence per period by sex and, age, were calculated (rates per 1,000,000 children/years). Results In total 2,615 new cases of cancer were registered, with the male/female ratio generally >1, but in some tumors there were more cases in females (retinoblastoma, germ cells tumors). The principal groups of neoplasms in seven jurisdictions were leukemias, central nervous system tumors (CNS tumors), and lymphomas, and the combined frequency for these three groups was 62.6 to 77.2%. Most frequently found (five jurisdictions) was the North American-European pattern (leukemias-CNS tumors-lymphomas). Eight jurisdictions had AAS within the range reported in the world literature. The highest incidence was found for children underless than five year of age. In eight jurisdictions, leukemia had high incidence (>50). The AAS of lymphomas was between 1.9 to 28.6. Chiapas and Guerrero had the highest AAS of CNS tumors (31.9 and 30.3, respectively). The frequency and incidence of neuroblastoma was low. Chiapas had the highest incidence of retinoblastoma (21.8). Germ-cell tumors had high incidence. Conclusion The North American-European pattern of cancers was the principal one found; the overall incidence was within the range reported worldwide. In general but particularly in two jurisdictions (Yucatán and Chiapas), it will be necessary to carry out studies concerning the causes of cancer in children. Due to the little that is known about the incidence of cancer in Mexican children, it will be necessary to develop a national program to establish a cancer registry for the whole of the country.

Fajardo-Gutiérrez Arturo; Juárez-Ocaña Servando; González-Miranda Guadalupe; Palma-Padilla Virginia; Carreón-Cruz Rogelio; Ortega-Alvárez Manuel; Mejía-Arangure Juan

2007-01-01

237

Ten marker compounds-based comparative study of green tea and guava leaf by HPTLC densitometry methods: antioxidant activity profiling.  

UK PubMed Central (United Kingdom)

High-performance thin layer chromatography (HPTLC) method for the separation and quantitative determination of ten markers (catechins, flavonoids, and phenolics) in different extracts of green tea and guava leaf has been developed and the antioxidant activity profiles of the two plant extracts have been determined. Ten marker compounds have been resolved using silica gel 60 F(254) plates, toluene/acetone/formic acid (5:4:1 ?v/v/v) for markers 1-6, and toluene/ethyl acetate/formic acid/methanol (3:3:0.8:0.2? v/v/v/v) for markers 7-10 as the mobile phases. The high-performance thin layer chromatography densitometry was performed at wavelengths of 282 and 285 ?nm for the markers 1-6 and 7-10, respectively. Potent antioxidant activity and the presence of phenolics and flavan-3-ols has been observed for the guava leaf extracts suggestive of its use as an alternate economical source of antioxidants over green tea--the well-established food additive/nutraceutical agent.

Khan I; Sangwan PL; Abdullah ST; Gupta BD; Dhar JK; Manickavasagar R; Koul S

2011-04-01

238

Ten marker compounds-based comparative study of green tea and guava leaf by HPTLC densitometry methods: antioxidant activity profiling.  

Science.gov (United States)

High-performance thin layer chromatography (HPTLC) method for the separation and quantitative determination of ten markers (catechins, flavonoids, and phenolics) in different extracts of green tea and guava leaf has been developed and the antioxidant activity profiles of the two plant extracts have been determined. Ten marker compounds have been resolved using silica gel 60 F(254) plates, toluene/acetone/formic acid (5:4:1 ?v/v/v) for markers 1-6, and toluene/ethyl acetate/formic acid/methanol (3:3:0.8:0.2? v/v/v/v) for markers 7-10 as the mobile phases. The high-performance thin layer chromatography densitometry was performed at wavelengths of 282 and 285 ?nm for the markers 1-6 and 7-10, respectively. Potent antioxidant activity and the presence of phenolics and flavan-3-ols has been observed for the guava leaf extracts suggestive of its use as an alternate economical source of antioxidants over green tea--the well-established food additive/nutraceutical agent. PMID:21384548

Khan, Imran; Sangwan, Payare L; Abdullah, Sheikh Tasduq; Gupta, Bhisan D; Dhar, Jagdish K; Manickavasagar, Rajendran; Koul, Surrinder

2011-03-07

239

Teaching pharmacology by case study.  

UK PubMed Central (United Kingdom)

This paper describes why case studies deserve a place in the centre of the bioscience curriculum, and how they have been used as a vehicle to improve care and save lives. A knowledge of drugs, their side-effects and interactions is becoming increasingly important to nurses. One powerful way to convey this information is the case study, which, despite its limitations, has the potential to endow difficult topics in therapeutics with the power of the narrative. The author suggests that case study projects encourage students to forge theory-practice links, related to their own specialist areas. When shared with their colleagues, these encourage the class by illustrating 'bioscience in action' and endowing the subject with the 'reality factor'. They also provide rich qualitative data for evaluating and delineating the curriculum. These case studies demonstrate the value of evidence-based practice; although case data is part of the evidence, it can never substitute for evidence-based practice. This paper builds on the findings of the author's PhD in postregistration nurse education; the examples described here are typical of 151 such cases in the research project.

Jordan S

1997-10-01

240

Experimental study of a fast plasma focus discharge operated in the range of tens of joules emitting neutrons  

International Nuclear Information System (INIS)

In this doctoral research, a small plasma focus discharge operated at tens of joules and kilo amperes has been experimentally studied. This device produces a coaxial discharge by an electrode arrange which consists of an inner electrode, a cylindrical insulator, and an outer electrode. The discharge is driven by a capacitive generator and it is operated at pressures of some millibars. Typical electrical parameters of the device are T/4?150ns, 160 nF, 40 nH, 30-100J, 40-70kA. When Deuterium is used as filling gas, neutrons are produced by fusion reactions. The device, namely PF-50J, is one of the most extreme plasma focus reported in the literature to emit neutrons. The results of this work have demonstrated that the same dynamics found in larger machines (operated from kJ to MJ) is also found in this extremely low energy device which means that after the discharge is initiated, a plasma sheet is formed over the insulator. By the action of the Lorentz force, the plasma sheet moves axially. When the sheet reaches the top end of the inner electrode, it starts to implode radially to finally form a dense plasma column (pinch). Finally, the plasma column is disrupted 5-10ns after column formation. Shock piston velocities of the order of 104-105m/s were estimated from experiments for each discharge dynamical phase. Typical pinch densities of 1024-25m-3 were also observed in PF-50J. An interesting feature observed in this work is the formation of axial jet-like structures which appears at late times almost hundred nanoseconds after pinch disruption. These structures are composed by a metallic plasma which results from ablation of the inner electrode. The mechanism responsible for the formation of this kind of structure is still unknown, although evidence suggests that the phenomena is not related to the pinch formation process. One of the principal motivations of this thesis was to study the optimization for neutron emission in the PF-50J device. This plasma focus is expected to yield 103-104 neutrons per pulse when is operated with deuterium. Standard detection techniques, for example neutron activation detectors, present detection limits higher than 105 neutrons per pulse, so it was necessary to develop a measurement method for higher efficiency detectors based on the use moderated proportional counter tubes for the purpose of neutron optimization. In contrast to low rate continuous regime, this detectors show pulse piling up when irradiated with pulsed neutrons, which make impossible to count events with standard nuclear electronics. In this thesis, it is presented a detailed study of pulsed piling up statistics in the proportional counter and a complete characterization of the 3He tubes based detection system. Regarding that the net area of detector output signal is proportional to the number of detected events, a counting model was developed and thus a methodology for measurement of the neutron yield is proposed. Special emphasis was put on the sources of fluctuation that affects the measurement process, which are given by the counting statistics, piling up statistics, and background electrical noise. As a result, the methodology allows measurements uncertainties for pulsed D-D fusion neutrons lower than 30% in the range of Y ? 3x103n/shot, reducing in this way by almost two order of magnitude the detection limit of the state of art techniques. A theoretical study of the detection frequency or reproducibility for pulsed neutron sources is also presented. Comparisons with results in PF-50J show that theoretical models for reproducibility are reasonable high boundary estimations for the experimental values. The optimization study is presented in the last part of this work. Optimal conditions for neutron emission were experimentally obtained. An interesting finding is the observation of two regimes for pinch formation and neutron emission. The first regime is related to the pinch formation close to the first current maximum in the first quarter of period, while in the second one these phenomena are observed at higher press

2011-01-01

 
 
 
 
241

Effects of tripolar TENS of vertebral column on slow and fast motor units: A preliminary study using H-reflex recovery curve method  

Directory of Open Access Journals (Sweden)

Full Text Available Introduction: Effect of tripolar TENS of vertebral column on slow and fast motoneurons (MNs) activity of soleus muscle was previously investigated. In this study for better differentiation of the behavior of slow and fast MNs, we exploited H-reflex recovery curve recording in two muscles of soleus and lateral gastrocnemius, respectively as the representatives of slow and fast muscles. Methods: 10 healthy non-athlete women aged 22.7±2.21 years participated in two (control and test) sessions. H-reflex recovery curve of soleus (slow) and gastrocnemius (fast) muscles were recorded before and 15 minutes after applying tripolar TENS (TENS frequency= 100 Hz and pulse width= 300 ?s) on vertebral column. For recording the curve, rectangular paired stimuli were applied on tibial nerve (ISI= 40-520, frequency= 0.2 Hz, pulse width= 600 ?s). Results: Our findings showed that maximum H-reflex recovery in gastrocnemius muscle appeared in shorter ISIs (240 ms), while in soleus muscle it appeared in longer ISIs (400 ms). H-reflex recovery curve amplitude slightly decreased after applying tripolar TENS. The comparison of H-reflex recovery curve of both soleus and gastrocnemius muscles either in control or test session did not show any significant difference (P>0.05). Conclusion: It is suggested that tripolar TENS excites not only the skin but also Ia and Ib afferents in the dorsal column. Synaptic interactions of these afferents in spinal cord cause the inhibition of type I MNs and facilitation of type II MNs.

Leila Simorgh; Giti Torkaman; Seyyed Mohammad Firoozabadi

2007-01-01

242

Probabilistic consequence study of residual radiological effects from a hypothetical ten-ton inadvertent nuclear yield. Weapons Safety Program  

International Nuclear Information System (INIS)

In this paper we study the potential radiological consequences of a strategic bomber accident, in which one of the assumed on-board nuclear weapons explodes with an arbitrarily chosen 10-ton nuclear yield. The frequency of such an occurrence is infinitesimal. The safety design features in today s nuclear weapons' systems essentially forbid its occurrence. We have a chosen a military base which has the feature of being a representative combination of urban and rural populations. The assumed ''crash site'' is near the northwest comer of the military base, close to civilian housing located just across the street from the base. A worst case wind would be from the ESE (east south east). This would cause fission debris to be dispersed toward the largest population centers and, thus, would lead to the largest Pu ''collective'' doses (i.e., a dose integrated over time and summed over individuals). Also, if an ESE wind were blowing at accident time, some people in nearby housing could receive lethal gamma-ray doses from fallout before evacuation could occur. It is assumed only one weapon undergoes nuclear yield; the other on-board weapons would HE detonate and the Pu would be aerosolized and lofted. We assume an activity-size distribution and lofting similar to those used to predict fallout measured at NTS. The main thrust of our study is to provide estimates of probabilistic radiological risks to the population local to a strategic bomber crash site. The studied radiological consequences are: cloud-passage doses from Pu inhalation; doses from groundshine due to gamma-producing radionuclides; and areal contamination from Pu and the long-lived fission products Cs-137 and Sr-90

1994-01-01

243

Case Study on Logistics Performance  

Directory of Open Access Journals (Sweden)

Full Text Available The paper presents research carried out at a medium?size manufacturing organization in east Asia. The study tries to highlight the importance of supply chain management; specifically, our aim for this study is to understand logistics and performance measurement in the logistics and supply chain, and we include a theoretical discussion of online data collected and a case study of the logistic performance of a real organization. The study also examines the performance of the selected company, identifies the problems and provides recommendations for improvements. This study can be a guide for business advisers and those interested in analysing company performance, especially from a logistics viewpoint. We also suggest the methodology of this case study for those who want to have a better understanding of a business environment before starting their own business, or for benchmarking practice during strategic planning.

Shahryar Sorooshian; Manimekalai Jambulingam; Javad Dodangeh

2013-01-01

244

5. A ten year study of the treatment of malaria in pregnancy at a secondary hospital in south west Nigeria  

Directory of Open Access Journals (Sweden)

Full Text Available Malaria in pregnancy has remained a major public health problem in Nigeria. The treatment of malaria in pregnancy at the Lady of Apostles Catholic Hospital, Oluyoro, Oke-Ofa, Ibadan in South West Nigeria between 1999 and 2008 was studied retrospectively. The objective of the study was to assess the rational use of anti-malarial drugs in the treatment of malaria in pregnancy. A total of 580 case notes of patients were collected from the medical records department. The most prevalent age group of between 15 and 20 years accounted for two hundred and two (202) (34.8%), while the least prevalent age group of between 41 and 45 years was 10 (1.7%). Majority of the patients 299 (39.5%) had secondary education, and those with tertiary education being 200 (34.5%). The gestational fetal age at which malaria infection was most prevalent was between 4 and 6 months, while the least prevalent gestational fetal age was between 7 and 9 months. There was a rapid but consistent decline in the use of Chloroquine forty eight (48) (23%) from 1999, to 3 (5%) in 2008. Sulfadoxine-Pyrimethamine 6 (3.8%) was observed to have a steady rise in use during the years 1999 to 30 (18.8%) in 2008. In 1999 and 2000 there was no ACT used. In 2001, 2 (0.9%) ACTs were used and increased significantly (p>0.01) to fifty three (53) (24.8%) in 2008. The community was averagely literacy and most of the women could therefore be trained on proper antenatal care through seminars and counseling thereby reducing the incidence of malaria in pregnancy.

M.K. Omole; O.D. Onwusah

2011-01-01

245

Endometriosis-associated ovarian cancer: A ten-year cohort study of women living in the Estrie Region of Quebec, Canada  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Objectives Endometriosis has been believed to increase the risk of developing ovarian cancer, but recent data supporting this hypothesis are lacking. The aim of this study was to verify whether the incidence of endometriosis, ovarian cancer and the both increased during the last 10 years among women living in the Estrie region of Quebec. Methods We collected data of women diagnosed with endometriosis, ovarian cancer or both, between 1997 and 2006, from a population living in the Estrie region of Quebec. We performed this retrospective cross-sectional study from the CIRESSS (Centre Informatisé de Recherche Évaluative en Services et Soins de Santé) system, the database of the CHUS (Centre Hospitalier Universitaire of Sherbrooke), Sherbrooke, Canada. Results Among the 2854 identified patients, 2521 had endometriosis, 292 patients had ovarian cancer and 41 patients had both ovarian cancer and endometriosis. We showed a constant increase in the number of ovarian cancer (OC) between 1997 and 2006 (r2 = 0.557, P = 0.013), which is not the case for endometriosis (ENDO) or endometriosis-associated ovarian cancer (EAOC). The mean age ± SD was 40.0 ± 9.9 and 53.9 ± 11.4 for patients having ENDO and OC, respectively. Mean age of women with EAOC was 48.3 ± 10.8, suggesting an early onset of ovarian cancer in women having endometriosis of about 5.5 years average, P = 0.003. Women with ENDO were at increased risk for developing OC (Rate Ratio [RR] = 1.6; 95% Confidence Interval [CI] = 1.12-2.09). Pathological analyses showed the predominance of endometrioid type (24.4%) and clear-cell type (21.9%) types in EAOC compared to OC, P = 0.0070 and 0.0029, respectively. However, the serous type is the most widespread in OC (44.5%) in comparison to EAOC (19.51%), P = 0.0023. Conclusion Our findings highlight that the number of cases of ovarian cancer is constantly increasing in the last ten years and that endometriosis represents a serious risk factor which accelerates its apparition by about 5.5 years.

Aris Aziz

2010-01-01

246

Pathology Case Study: Postmenopausal Bleeding  

Science.gov (United States)

This gynecologic pathology case study, provided by the University of Pittsburgh Department of Pathology, is an excellent resource for students and instructors in the health science fields. This case involves 57-year-old female with postmenopausal bleeding. The patientâÂÂs history, and results from a pelvic ultrasound are included in the case study to aid in the understanding of the final diagnosis. The official final diagnosis is accompanied by a discussion of the contributing doctorâÂÂs findings and a list of references. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose patientâÂÂs conditions.

Kanbour, Anisa; Chen, Lei; Kessinger, Rovena L.

2008-12-15

247

Structure is three to ten times more conserved than sequence--a study of structural response in protein cores.  

UK PubMed Central (United Kingdom)

Protein structures change during evolution in response to mutations. Here, we analyze the mapping between sequence and structure in a set of structurally aligned protein domains. To avoid artifacts, we restricted our attention only to the core components of these structures. We found that on average, using different measures of structural change, protein cores evolve linearly with evolutionary distance (amino acid substitutions per site). This is true irrespective of which measure of structural change we used, whether RMSD or discrete structural descriptors for secondary structure, accessibility, or contacts. This linear response allows us to quantify the claim that structure is more conserved than sequence. Using structural alphabets of similar cardinality to the sequence alphabet, structural cores evolve three to ten times slower than sequences. Although we observed an average linear response, we found a wide variance. Different domain families varied fivefold in structural response to evolution. An attempt to categorically analyze this variance among subgroups by structural and functional category revealed only one statistically significant trend. This trend can be explained by the fact that beta-sheets change faster than alpha-helices, most likely due to that they are shorter and that change occurs at the ends of the secondary structure elements.

Illergård K; Ardell DH; Elofsson A

2009-11-01

248

eCompetence Case Studies  

DEFF Research Database (Denmark)

In this paper we present some details of the processes undertaken in the European eCompetence Initiative. We present two illustrative and representative case studies. The research aims to identify and understand patterns of individual and organisational eCompetence approaches.

Jensen, Helle Bækkelund

2006-01-01

249

[Analysis of publications on infectious diseases. A comparative study of ten countries in the period 2000-2009].  

UK PubMed Central (United Kingdom)

OBJECTIVE: We analyse the productivity and visibility of Spanish publications on the subject category of infectious diseases in the period 2000-2009 and compared with the corresponding nine other countries. METHODS: We used the database Web of Science. Analysis (annual and five-year) was restricted to the citable documents. The bibliometric indicators used were the number of publications, the amount of citations, median and interquartile range of the citations and the h-index Hirsch. RESULTS: There were 76,491 publications (84.1% were original articles) with a percentage increase of 20% between the two periods. The ten countries with over 50,000 citations were the United States, United Kingdom, France, Germany, Canada, Holland, Spain, Italy, Switzerland and Australia. 24.8% of publications in international collaboration was made and received 29.9% of the total citations. 47.1% of the publications corresponding to the first quartile journals and received 68.1% of the total citations. The median of citations for all publications was 9 (interquartile range: 4-21). Spain was the fifth country in the world by number of publications, the seventh by citations received, and the eighth by the h index. Spain was the country with the lowest percentage of publications in the first quartile (40.2%), and international collaboration (26.7%). CONCLUSIONS: In the period 2000-2009 analysed we observed a high production of publications by Spanish authors, with a high growth rate, and a prominent position in the total number of citations received by publications.

Iñigo J; Chaves F

2012-05-01

250

Meningite bacteriana neonatal agentes etiológicos em 109 casos durante período de dez anos Raterial meningitis in newborn infants: etiologic agents in 109 cases throughout ten years  

Directory of Open Access Journals (Sweden)

Full Text Available A etiologia das meningites purulentas foi analisada em 109 recém-nascidos admitidos em unidade de cuidados intensivos neonatais durante período de dez anos. Bactérias foram recuperadas do LCR de 57 (52,2%) recém-nascidos. Verificou-se predomínio dos bacilos Gram-negativos isolados em 38 (34,9%); cocos Gram-positivos foram isolados em somente 12 (11,0%). Os microorganismos tidos como de contaminação hospitalar - Klebsiella sp, Salmonella sp, Enterobacter sp, Pseudomonas sp, Flavobacterium meningosepticum e Ser-ratia marcescens responderam pela etiologia presumível em 38 (49,3%) dentre 77 pacientes com culturas positivas; foram isolados de 22 (7,0%) recém-nascidos com procedência hospitalar imediata e somente em 12 (34,3%) daqueles vindos diretamente do domicílio (X2 = 4,08; pThe etiology of purulent meningitis was investigated in 109 newborn infants admitted in a neonatal intensive care unit throughout a ten year period. Bacterial pathogens were isolated from the CSF in 57 (52.2%) neonates. There was a predominance of Gram-negative bacilli isolated in 38 (34.9%) neonates. Gram-positive cocci were isolated from CSF in only 12 (11.0%) neonates. Microorganisms associated with nosocomial septicemia and meningitis in neonates - Klebsiella sp, Salmonella sp, Enterobacter sp, Pseudomonas sp, Flavobacterium meningosepticum and Sematia marcescens - were responsible for presumptive etiology in 38 (49.3%) among 77 patients with positive cultures in "closed sites". They were isolated from 22 (57.0%) neonates with prior hospitalization but only from 12 (34.3%) neonates coming directly from their households (X2==4.08; p<0.05). The mortality rate was significantly higher in patients with positive CSF cultures (47.4%) in comparison to patients with negative cultures (18.4%) (X2 = 5.01; p<(0.05). It is possible to conclude that Gram-negative bacilli, many of then of hospitalar origin, are the major pathogens in this study. An improvement on neonatal health care and a scrupulous control of neonatal nosocomial infections are recommended.

Sonia R. T. Silva Ramos; Rubens Feferbaum; Antranik Manissadjian; Flávio A. Costa Vaz

1992-01-01

251

Minimum ten-year results of a prospective randomised study of autologous chondrocyte implantation versus mosaicplasty for symptomatic articular cartilage lesions of the knee.  

UK PubMed Central (United Kingdom)

Autologous chondrocyte implantation (ACI) and mosaicplasty are methods of treating symptomatic articular cartilage defects in the knee. This study represents the first long-term randomised comparison of the two techniques in 100 patients at a minimum follow-up of ten years. The mean age of the patients at the time of surgery was 31.3 years (16 to 49); the mean duration of symptoms pre-operatively was 7.2 years (9 months to 20 years). The lesions were large with the mean size for the ACI group being 440.9 mm(2) (100 to 1050) and the mosaicplasty group being 399.6 mm(2) (100 to 2000). Patients had a mean of 1.5 previous operations (0 to 4) to the articular cartilage defect. Patients were assessed using the modified Cincinnati knee score and the Stanmore-Bentley Functional Rating system. The number of patients whose repair had failed at ten years was ten of 58 (17%) in the ACI group and 23 of 42 (55%) in the mosaicplasty group (p < 0.001). The functional outcome of those patients with a surviving graft was significantly better in patients who underwent ACI compared with mosaicplasty (p = 0.02).

Bentley G; Biant LC; Vijayan S; Macmull S; Skinner JA; Carrington RW

2012-04-01

252

[PFAPA syndrome: study of 10 cases].  

UK PubMed Central (United Kingdom)

BACKGROUND AND OBJECTIVES: «PFAPA syndrome» is an autoinflammatory entity consisting of periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis. Its etiology is unknown although a dysregulation in the control of the autoinflammatory response seems to play a role. Although a genetic origin is suspected, no specific mutation has been determined yet. Corticosteroids are the mainstay of the treatment during the acute attacks. However, in long-term follow-up the role of tonsillectomy is controversial. PATIENTS AND METHODS: A retrospective study of the pediatric cases diagnosed with the PFAPA syndrome was performed in our center during the last 4 years. RESULTS: Ten patients were diagnosed with the syndrome who received corticosteroids as the only treatment with improvement and favourable prognosis. CONCLUSION: PFAPA syndrome is the most common periodic fever disorder described in childhood whose genetic background has not been yet clarified. Our contribution with 10 patients further supports the common existence of this entity and the need to keep it in mind when having recurrent fevers.

Antón-Martín P; Ortiz Movilla R; Álvarez García A; Guillén Martín S; Ruiz Jiménez M; Ramos Amador JT

2012-02-01

253

A case study of Impetigo  

Directory of Open Access Journals (Sweden)

Full Text Available This is a report of a case study on 234 patients with impetigo who referred to Razi Dermatology Hospital from April to November, 1989. Treatment was started immediately after obtaining direct smear and performing culture and antibiotic sensitivity test. The most common organism responsible for impetigo was the coagulase-positive staphylococcus (71%). In 13.7% of the cases, the coagulase-negative staphylococcus was grown on culture media, but none of the cultures showed streptococcus as the main organism. Treatment was started with oral penicillin V, oral erythromycin, benzathine penicillin G injection, oral cephalexin, and topical fuccidin. Clinical and bacteriological evaluation after 3-7 days showed that it is preferable to use oral cephalexin instead of other protocols such as oral erythromycin, which has previously been the drug of choice for impetigo. In addition, topical fuccidin with a 75% curative rate was the first drug for treatment, with the same effect as the oral cephalexin

Mansouri P

1993-01-01

254

Pathology Case Study: Cushing's Syndrome  

Science.gov (United States)

The Department of Pathology at the University of Pittsburgh Medical Center has compiled a wide range of pathology case studies to aid students and instructors in the medical/health science field. This particular case involves a 41 year-old woman experiencing the following symptoms for a period of 18 months: fatigue, weakness, lethargy, and decreased concentration. The patientâÂÂs history, description of CT scans, and images from histological examinations, which contributed to the conclusive diagnosis, are all provided here for your review. The contributing doctors provide a detailed discussion of the patientâÂÂs condition in the âÂÂFinal Diagnosisâ section. Students will find this resource especially helpful, as it provides experience with patient history, lab results, and diagnostics.

Dacic, Sanja; Rajan, Prabha B.

2009-08-27

255

Pathology Case Study: Respiratory Distress  

Science.gov (United States)

This cardiovascular pathology case study, provided by the University of Pittsburgh Department of Pathology, is an excellent resource for students and instructors in the health science fields. A 72-year-old female experiencing respiratory distress is the focus of this case. The patientâÂÂs history, gross description, and microscopic description of test results are provided to aid readers in understanding the patientâÂÂs diagnosis. The official final diagnosis is accompanied by a discussion of the contributing doctorâÂÂs findings and a list of references. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose patientâÂÂs conditions.

Ariyanayagam-Baksh, Shashi

2009-05-07

256

Childhood and adult tuberculosis in a rural hospital in Southeast Ethiopia: a ten-year retrospective study  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background Many DOTS experiences in developing countries have been reported. However, experience in a rural hospital and information on the differences between children and adults are limited. We described the epidemiology and treatment outcome of adult and childhood tuberculosis (TB) cases, and identified risk factors associated with defaulting and dying during TB treatment in a rural hospital over a 10-year period (1998 to 2007). Methods Retrospective data collection using TB registers and treatment cards in a rural private mission hospital. Information was collected on number of cases, type of TB and treatment outcomes using standardised definitions. Results 2225 patients were registered, 46.3% of whom were children. A total of 646 patients had smear-positive pulmonary TB (PTB), [132 (20.4%) children]; 816 had smear-negative PTB [556 (68.2%) children], and 763 extra-PTB (EPTB) [341 (44.8%) children]. The percentage of treatment defaulters was higher in paediatric (13.9%) than in adult patients (9.3%) (p = 0.001). The default rate declined from 16.8% to 3.5%, and was independently positively associated with TB meningitis (AOR: 2.8; 95% CI: 1.2-6.6) and negatively associated with smear-positive PTB (AOR: 0.6; 95% CI: 0.4-0.8). The mortality rate was 5.3% and the greatest mortality was associated with adult TB (AOR: 1.7; 95% CI: 1.1-2.5), TB meningitis (AOR: 3.6; 95% CI:1.2-10.9), and HIV infection (AOR: 4.3; 95% CI: 1.9-9.4). Decreased mortality was associated with TB lymphadenitis (AOR: 0.24; 95% CI: 0.11-0.57). Conclusion (1) The registration of TB cases can be useful to understand the epidemiology of TB in local health facilities. (2) The defaulter and mortality rate of childhood TB is different to that of adult TB. (3) The rate of defaulting from treatment has declined over time.

Ramos Jose; Reyes Francisco; Tesfamariam Abraham

2010-01-01

257

Powers of ten  

CERN Multimedia

Powers of Ten is a 1977 short documentary film written and directed by Charles Eames and his wife, Ray. The film depicts the relative scale of the Universe in factors of ten (see also logarithmic scale and order of magnitude). The idea for the film appears to have come from the 1957 book Cosmic View by Kees Boeke. The film begins with an aerial image of a man reclining on a blanket; the view is that of one meter across. The viewpoint, accompanied by expository voiceover, then slowly zooms out to a view ten meters across ( or 101 m in standard form), revealing that the man is picnicking in a park with a female companion. The zoom-out continues, to a view of 100 meters (102 m), then 1 kilometer (103 m), and so on, increasing the perspectiveâ??the picnic is revealed to be taking place near Soldier Field on Chicago's waterfrontâ??and continuing to zoom out to a field of view of 1024 meters, or the size of the observable universe. The camera then zooms back in to the picnic, and then to views of negative pow...

Innocenti, Pier Giorgio

1979-01-01

258

Powers of ten  

CERN Multimedia

Powers of Ten is a 1977 short documentary film written and directed by Charles Eames and his wife, Ray. The film depicts the relative scale of the Universe in factors of ten (see also logarithmic scale and order of magnitude). The film begins with an aerial image of a man reclining on a blanket; the view is that of one meter across. The viewpoint, accompanied by expository voiceover, then slowly zooms out to a view ten meters across ( or 101 m in standard form), revealing that the man is picnicking in a park with a female companion. The zoom-out continues, to a view of 100 meters (102 m), then 1 kilometer (103 m), and so on, increasing the perspectiveâ??the picnic is revealed to be taking place near Soldier Field on Chicago's waterfrontâ??and continuing to zoom out to a field of view of 1024 meters, or the size of the observable universe. The camera then zooms back in to the picnic, and then to views of negative powers of tenâ??10-1 m (10 centimeters), and so forth, until we are viewing a carbon nucl...

Pyramid FILMS

1977-01-01

259

Modulation of laser-evoked potentials and pain perception by transcutaneous electrical nerve stimulation (TENS): a placebo-controlled study in healthy volunteers.  

UK PubMed Central (United Kingdom)

OBJECTIVE: To investigate the effects of transcutaneous electrical nerve stimulation (TENS) on brain nociceptive responses (laser-evoked potentials, LEPs) and pain perception. METHODS: Twenty healthy subjects were included. Nociceptive CO(2)-laser pulses were sequentially delivered to the dorsum of both feet. The amplitude of LEPs and nociceptive thresholds were collected in three consecutive conditions: T1: "sham" TENS (2 Hz/low-intensity) positioned heterotopically, over the left thigh; T2: "active" TENS (120 Hz/low-intensity) applied homotopically, over the left common peroneal nerve; and T3: "sham" TENS (replication of condition T1). RESULTS: Compared with "sham" TENS, "active" TENS significantly decreased the LEPs amplitude. This effect was observed exclusively when "active" TENS was applied ipsilaterally to the painful stimulus. Nociceptive thresholds increased with sessions in both limbs, but the increase observed during the "active" condition of TENS (T2) exceeded significantly that observed during the condition T3 only on the foot ipsilateral to TENS. CONCLUSIONS: Compared with a credible placebo TENS, high-frequency TENS induced a significant attenuation of both the acute pain and LEPs induced by noxious stimuli applied on the same dermatome. SIGNIFICANCE: This modulation of subjective and objective concomitants of pain processing reflects a real neurophysiological TENS-related effect on nociceptive transmission.

Vassal F; Créac'h C; Convers P; Laurent B; Garcia-Larrea L; Peyron R

2013-09-01

260

The immune system status under the effect of low-level radiation: studies within the ten-kilometer zone of Chernobyl disaster  

International Nuclear Information System (INIS)

A study was made of the influence of high radiation contamination within the ten-kilometer zone of Chernobyl disaster on the structure and function of the immune system of mice. The cumulative radiation doses with respect to ?-radiation, were 0.024, 0.168 and 0.336 Gy. T-lymphocyte proliferation was shown to be activated with all radiation doses mentioned above but with doses of 0.024 and 0.168 Gy, helper T lymphocytes, and with 0.336 Gy, suppressor N-lymphocytes were primarilly activated. 9 refs., 7 figs., 2 tabs

1993-01-01

 
 
 
 
261

The Case: Generalisation, Theory and Phronesis in Case Study  

Science.gov (United States)

|Arguments for the value of case study are vitiated by assumptions about the need for generalisation in the warrant of social scientific inquiry--and little generalisation is legitimate from case study, although an argument exists for the role of the case in the establishment of a form of generalisation in a certain kind of theory, a line of…

Thomas, Gary

2011-01-01

262

Overview of the Case Studies  

DEFF Research Database (Denmark)

A series of case studies are used to illustrate many of the underlying modelling principles within the book. To facilitate this, the ICAS-MoT modelling tool has been used. A wide range of application areas have been chosen to ensure that the principal concepts of effective and efficient modelling are exercised. Conceptual frameworks for single and multiscale problems are given and explained. The importance of the steps is also explained, through annotated schematic diagrams. The important issues around workflow and data flow are given in diagrammatic form.

Cameron, Ian; Gani, Rafiqul

2011-01-01

263

Case studies in canonical stewardship.  

UK PubMed Central (United Kingdom)

In facing the challenges that confront Catholic health care today, it is important to know which civil law forms will assist in preserving the Church's ministry. The proper meshing of civil law and canon law thus provides a vehicle to strengthen the apostolate's work. The case studies presented here suggest several means of applying the principles in the new Code of Canon Law to three potentially problematic situations: the merger of a Catholic and non-Catholic hospital, the leasing of a Catholic hospital to an operating company, and the use of the multicorporate format.

Cafardi NP; Hite J

1985-11-01

264

Pathology Case Study: Metastasizing Tumor  

Science.gov (United States)

This is a case study presented by the University of Pittsburgh Department of Pathology in which a woman presented with a low-grade sarcoma with features of plexiform fibrohistiocytic tumor in the subcutaneous soft tissue of left posterior thigh. Visitors can view both gross and microscopic descriptions, including images, and have the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose disease. It is also a helpful site for educators to introduce or test students of soft tissue pathology.

Rao, Uma N.; Rostami, Sassan

2009-02-17

265

Pathology Case Study: Mediastinal Mass  

Science.gov (United States)

This is a case study presented by the University of Pittsburgh Department of Pathology in which a man complained of diaphoresis nausea and substernal chest pain through his left arm. Subsequent tests revealed a mediastinal mass with both fatty and solid components. Visitors can view both microscopic and gross descriptions, including images, and have the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose disease. It is also a helpful site for educators to introduce or test students of soft tissue pathology.

Rao, Uma N.; Fowler, Jason C.

2008-12-25

266

Pathology Case Study: Coccygeal Mass  

Science.gov (United States)

This is a case study presented by the University of Pittsburgh Department of Pathology in which a 60-year-old man has a recently enlarging coccygeal mass. Visitors are given both the microscopic and gross descriptions, including images, and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose disease. It is also a helpful site for educators to use to introduce or test student learning in skeletal and soft tissue pathology.

Horn, Kevin D.

2007-09-04

267

Pathology Case Study: Dilated Cardiomyopathy  

Science.gov (United States)

This is a case study presented by the University of Pittsburgh Department of Pathology in which a man presented with a large range of symptoms from chills and fever to underdeveloped calf muscles. Visitors are given both the microscopic and gross descriptions, including images, and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose disease. It is also a helpful site for educators to use to introduce or test student learning in cardiovascular pathology.

Lee, Robert E.; Defrances, Marie C.

2008-05-14

268

Pathology Case Study: Renal Failure  

Science.gov (United States)

This is a case study presented by the University of Pittsburgh Department of Pathology in which a 36-year-old man has had two kidney transplants. Visitors are given both the microscopic and gross descriptions, including images, and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose disease. It is also a helpful site for educators to use to introduce or test student learning in transplant pathology.

Richert, Charles A.

2007-08-27

269

Pathology Case Study: Testicular Mass  

Science.gov (United States)

This is a case study presented by the University of Pittsburgh Department of Pathology in which a 18-year-old male with "painless enlargement of the right testes over a period of several months, initially attributed to a sports injury." Visitors are given admission data along with gross and microscopic description, including images and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose disease. It is also a helpful site for educators to use to introduce or test student learning in genitourinary pathology.

Rao, Uma N.; Halpern, Melissa B.; Fowler, Jason C.

2008-08-19

270

Pathology Case Study: Renal Insufficiency  

Science.gov (United States)

This is a case study presented by the University of Pittsburgh Department of Pathology in which a 74-year-old man has been referred to the hospital for renal insufficiency complicating scleroderma. Visitors are given both the microscopic and gross descriptions, including images, and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose disease. It is also a helpful site for educators to use to introduce or test student learning in renal pathology.

Perry, Linda; Bastacky, Sheldon

2007-09-03

271

Pathology Case Study: Abdominal Mass  

Science.gov (United States)

This is a case study presented by the University of Pittsburgh Department of Pathology in which an older woman developed a renal mass without evidence of angiomyolipoma. Visitors are given both the microscopic and gross descriptions, including images, and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose disease. It is also a helpful site for educators to use to introduce or test student learning in endocrine pathology.

Hardy, Hunter T.

2008-10-16

272

Pathology Case Study: Lung Abscess  

Science.gov (United States)

This is a case study presented by the University of Pittsburgh Department of Pathology in which a 39-year-old man has died from lung abscess after treatment failed, and an autopsy was authorized. Visitors are given the microscopic and gross descriptions, including images, and are given the opportunity to identify the cause of death. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose disease. It is also a helpful site for educators to use to introduce or test student learning in autopsy pathology.

Lee, Robert E.; Graur, Octavia

2008-03-04

273

Pathology Case Study: Chronic Sinusitis  

Science.gov (United States)

This is a case study presented by the University of Pittsburgh Department of Pathology in which a man reported a history of chronic sinusitis that was not responding to nasal and antibiotic treatments. Visitors can view both microscopic and gross descriptions, including images, and have the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose disease. It is also a helpful site for educators to introduce or test students of head and neck pathology.

Fowler, Jason C.; Becich, Michael J.

2008-04-28

274

Pathology Case Study: Pancreatic Mass  

Science.gov (United States)

This is a case study presented by the University of Utah Department of Pathology in which a woman developed jaundice while on vacation. Subsequent testing revealed a pancreatic mass. Visitors can view both microscopic and gross descriptions, including images, and have the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose disease. It is also a helpful site for educators to introduce or test students of autopsy pathology.

Klatt, Edward C., 1951-

2008-12-31

275

Pathology Case Study: Renal Mass  

Science.gov (United States)

This is a pediatric pathology case study presented by the University of Pittsburgh Department of Pathology in which a 19-month-old boy has a renal mass. Visitors are given both the microscopic and gross descriptions, including images, and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using laboratory results to diagnose. It is also a helpful site for educators to use to introduce or test student learning in pediatric pathology.

Dickman, Paul S.; Christakos, Peter

2009-08-17

276

Pathology Case Study: Back Pain  

Science.gov (United States)

This is a case study presented by the University of Pittsburgh Department of Pathology, which describes a 62-year-old woman who presented with two months of back pain. Visitors are given patient history, laboratory findings, along with gross and microscopic descriptions, including images, and are given the opportunity to diagnose the patient. A "Final Diagnosis" section provides a discussion of the findings as well as references. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose disease. It is also a helpful site for educators to use to introduce or test student learning in pulmonary pathology.

Schoedel, Karen; Lu, Zhengbin

2009-04-17

277

Pathology Case Study: Transfusion Reaction  

Science.gov (United States)

This is a case study presented by the University of Pittsburgh Department of Pathology in which a young woman experienced vomiting, dizziness, headaches, and change of mental status due to conjunctival petechiae. Visitors are given the transfusion reaction investigation, and have the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose disease. It is also a helpful site for educators to use to introduce or test student learning in transfusion pathology.

Triulzi, Darrell; Johnson, Douglas R.

2008-09-02

278

Pathology Case Study: Pigmented Lesion  

Science.gov (United States)

This is a case study presented by the University of Pittsburgh Department of Pathology in which a 69-year-old man has a pigmented lesion on his right ear. Visitors are given the patient history and microscopic description, including images, and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose disease. It is also a helpful site for educators to use to introduce or test student learning in dermatologic pathology.

Ejadi, Samuel

2007-09-12

279

Pathology Case Study: Liver Transplant  

Science.gov (United States)

This is a case study presented by the University of Pittsburgh Department of Pathology in which a 34-year-old is experiencing complications following a liver transplant. Visitors are given both the microscopic and gross descriptions, including images, and are given the opportunity to diagnose the patient. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose disease. It is also a helpful site for educators to use to introduce or test student learning in transplant pathology.

Richert, Charles A.

2007-08-22

280

Organisational Communication: A Case Study  

Directory of Open Access Journals (Sweden)

Full Text Available The organization chosen for this case study on organizational communication is a small political activists' organization for which the writer of this paper once volunteered. The organizational communication problem encountered was that the volunteer supervisor did not have projects ready during the scheduled volunteer time slots, and despite a thorough interview process to determine skill-need matches and prior verbal scheduling of volunteer times, this problem persisted for months. With the lack of a communication plan, the consequence was a diminished enthusiasm for the cause and growing level of frustration causing this writer to cease volunteering for the organization despite having a true belief in its mission.

By Thomas A. Booth

2008-01-01

 
 
 
 
281

Disaster exposure as a risk factor for mental health problems, eighteen months, four and ten years post-disaster – a longitudinal study  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background Disaster experiences have been associated with higher prevalence rates of (mental) health problems. The objective of this study was to examine the independent relation between a series of single disaster experiences versus the independent predictive value of a accumulation of disaster experiences, i.e. a sum score of experiences and symptoms of distress and post-traumatic stress disorder (PTSD). Methods Survivors of a fireworks disaster participated in a longitudinal study and completed a questionnaire three weeks (wave 1), eighteen months (wave 2) and four years post-disaster (wave 3). Ten years post-disaster (wave 4) the respondents consisted of native Dutch survivors only. Main outcome measures were general distress and symptoms of PTSD. Results Degree of disaster exposure (sum score) and some disaster-related experiences (such as house destroyed, injured, confusion) were related to distress at waves 2 and 3. This relation was mediated by distress at an earlier point in time. None of the individual disaster-related experiences was independently related to symptoms of distress. The association between the degree of disaster exposure and symptoms of PTSD at waves 2 and 3 was still statistically significant after controlling for symptoms of distress and PTSD at earlier point in time. The variable ‘house destroyed’ was the only factor that was independently related to symptoms of PTSD at wave 2. Ten years after the disaster, disaster exposure was mediated by symptoms of PTSD at waves 2 and 3. Disaster exposure was not independently related to symptoms of PTSD ten years post-disaster. Conclusions Until 4 years after the disaster, degree of exposure (a sum score) was a risk factor for PTSD symptoms while none of the individual disaster experiences could be identified as an independent risk factor. Ten years post-disaster, disaster exposure was no longer an independent risk factor for symptoms of PTSD. Since symptoms of PTSD and distress at earlier waves perpetuate the symptoms at later waves, health care workers should aim their resources at those who still have symptoms after one and a half year post-disaster, to prevent health problems at medium and long-term.

van den Berg Bellis; Wong Albert; van der Velden Peter G; Boshuizen Hendriek C; Grievink Linda

2012-01-01

282

Disaster exposure as a risk factor for mental health problems, eighteen months, four and ten years post-disaster--a longitudinal study.  

UK PubMed Central (United Kingdom)

BACKGROUND: Disaster experiences have been associated with higher prevalence rates of (mental) health problems. The objective of this study was to examine the independent relation between a series of single disaster experiences versus the independent predictive value of a accumulation of disaster experiences, i.e. a sum score of experiences and symptoms of distress and post-traumatic stress disorder (PTSD). METHODS: Survivors of a fireworks disaster participated in a longitudinal study and completed a questionnaire three weeks (wave 1), eighteen months (wave 2) and four years post-disaster (wave 3). Ten years post-disaster (wave 4) the respondents consisted of native Dutch survivors only. Main outcome measures were general distress and symptoms of PTSD. RESULTS: Degree of disaster exposure (sum score) and some disaster-related experiences (such as house destroyed, injured, confusion) were related to distress at waves 2 and 3. This relation was mediated by distress at an earlier point in time. None of the individual disaster-related experiences was independently related to symptoms of distress. The association between the degree of disaster exposure and symptoms of PTSD at waves 2 and 3 was still statistically significant after controlling for symptoms of distress and PTSD at earlier point in time. The variable 'house destroyed' was the only factor that was independently related to symptoms of PTSD at wave 2. Ten years after the disaster, disaster exposure was mediated by symptoms of PTSD at waves 2 and 3. Disaster exposure was not independently related to symptoms of PTSD ten years post-disaster. CONCLUSIONS: Until 4 years after the disaster, degree of exposure (a sum score) was a risk factor for PTSD symptoms while none of the individual disaster experiences could be identified as an independent risk factor. Ten years post-disaster, disaster exposure was no longer an independent risk factor for symptoms of PTSD. Since symptoms of PTSD and distress at earlier waves perpetuate the symptoms at later waves, health care workers should aim their resources at those who still have symptoms after one and a half year post-disaster, to prevent health problems at medium and long-term.

van den Berg B; Wong A; van der Velden PG; Boshuizen HC; Grievink L

2012-01-01

283

A parathyroid scintigraphy case study  

International Nuclear Information System (INIS)

Background: There has been much debate concerning the most suitable protocol for parathyroid scintigraphy; the merits of various radiopharmaceuticals versus the correct imaging protocol to visualise both ectopic and anatomically placed adenomas against the various equipment choices have been debated. Aim: To demonstrate, through the use of a case study, the necessity of changing imaging protocols for parathyroid scintigraphy where a definitive imaging diagnosis is absent in the face of strong clinical suspicion. Method: Use is made of Tc99mMIBI, full field chest scintigraphy, a clearly defined imaging protocol and SPECT imaging to locate ectopic parathyroid tissue in a female patient with significant symptoms of parathyroid hyperfunction. Results: A single hyperfunctioning adenoma is located in the pre-carinal area of the mediastinum. Using a radioguided surgical technique the hyperfunctioning tissue is excised and confirmed by histopathology. Conclusion: Whilst a dramatic reduction in patient symptoms was not seen immediately in this patient, the symptoms of the illness have been subsiding since January 2003. This case study demonstrates the necessity of changing imaging protocols for parathyroid scintigraphy where a definitive imaging diagnosis is absent in the face of strong clinical suspicion.

2005-01-01

284

A parathyroid scintigraphy case study  

Energy Technology Data Exchange (ETDEWEB)

Background: There has been much debate concerning the most suitable protocol for parathyroid scintigraphy; the merits of various radiopharmaceuticals versus the correct imaging protocol to visualise both ectopic and anatomically placed adenomas against the various equipment choices have been debated. Aim: To demonstrate, through the use of a case study, the necessity of changing imaging protocols for parathyroid scintigraphy where a definitive imaging diagnosis is absent in the face of strong clinical suspicion. Method: Use is made of Tc99mMIBI, full field chest scintigraphy, a clearly defined imaging protocol and SPECT imaging to locate ectopic parathyroid tissue in a female patient with significant symptoms of parathyroid hyperfunction. Results: A single hyperfunctioning adenoma is located in the pre-carinal area of the mediastinum. Using a radioguided surgical technique the hyperfunctioning tissue is excised and confirmed by histopathology. Conclusion: Whilst a dramatic reduction in patient symptoms was not seen immediately in this patient, the symptoms of the illness have been subsiding since January 2003. This case study demonstrates the necessity of changing imaging protocols for parathyroid scintigraphy where a definitive imaging diagnosis is absent in the face of strong clinical suspicion.

O' Leary, Desiree [UCD School of Diagnostic Imaging, St Anthony' s Campus, Herbert Avenue, Dublin 4 (Ireland)]. E-mail: desiree.oleary@ucd.ie

2005-05-01

285

The association of microalbuminuria with mortality in patients with acute myocardial infarction. A ten-year follow-up study  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Our study evaluates the long-term effect of microalbuminuria on mortality among patients with acute myocardial infarction. We followed 151 patients from 1996 to 2007 to investigate if microalbuminuria is a risk factor in coronary heart disease. All patients admitted with acute myocardial infarction ...

Mustafa Taskiran; Allan Iversen; Klaus Klausen; Gorm B. Jensen; Jan Skov Jensen

286

Networks for Innovation for Sustainable Tourism : Case Studies and Cross-Case Analysis  

DEFF Research Database (Denmark)

Innovation is key to responding to the future challenges that confront all sectors of society and the economy. Within tourism, there are numerous corporations and destinations around the world that are responding to the challenges posed by ecological, social, cultural and economic forces and making the transformation toward sustainability through innovation. Networks for Innovation in Sustainable Tourism assembles ten case studies of large and small enterprises and destinations in developed and developing nations that are pursuing innovative practices that will enhance the sustainability of their operations. The cases have been prepared for use in research and teaching of innovation, and the analysis and case notes are designed to facilitate discussion and further investigation of innovation, not only in tourism, but in other economic sectors as well.

Liburd, Janne J.; Carlsen, Jack

2013-01-01

287

The effect of manganese on the central nervous system. On the basis of ten cases with hyperintensities in the globus pallidus and a part of the brainstem on T1-weighted magnetic resonance imaging  

Energy Technology Data Exchange (ETDEWEB)

We examined the effect of manganese (Mn) on the central nervous system, on the basis of ten cases with hyperintensities in the globus pallidus and a part of the brainstem on T1-weighted magnetic resonance imaging (MRI). These cases were divided into three groups; four cases with liver dysfunction, three cases with intravenous infusion containing Mn and three cases without any specific factor. Mn levels were measured in serum, whole blood and cerebrospinal fluid (CSF). As a result, their serum and CSF Mn levels were significantly higher (P<0.05 and P<0.01, respectively) than those of the control subjects, while their whole blood Mn levels were not significantly different. Single photon emission computed tomography demonstrated a decrease of the cerebral blood flow in the frontal lobe in four cases with the hyperintensities and in one of them the decrease improved after the disappearance of the hyperintensity. Oculogyric crisis in one case with intravenous infusion containing Mn and dystonia in one case without any specific factor also improved, when the hyperintensities disappeared. In the cases with T1-weighted MRI hyperintensities, it is important to measure serum and CSF Mn levels as well as to observe psychiatric and neurological symptoms. (author)

Katsuragi, Toshio [Yokohama City Univ. (Japan). School of Medicine

1998-03-01

288

[Seven or ten days? Cost-effectiveness study on the duration of H. pylori treatment in primary care].  

UK PubMed Central (United Kingdom)

OBJECTIVE: To determine through an economic evaluation study whether it is cost-effective to extend treatment of dyspeptic patients from 7 to 10 days, distinguishing between functional dyspepsia, unexamined dyspepsia, and ulcer disease. DESIGN: Cost-effectiveness study by means of a decision 3 comparing direct costs per patient cured with 2 strategies: a) 7 days treatment versus b) 10 days. Two-year study in the National Health System. SETTING: Primary care. PARTICIPANTS: One-hundred patients with peptic ulcer, functional dyspepsia, or unexamined dyspepsia who received treatment for H pylori infection. INTERVENTIONS: H pylori eradication treatment with a proton pump inhibitor, clarithromycin, and amoxycillin for 7 or 10 days. Measurement variable: incremental cost per patient cured. RESULTS: In peptic ulcer patients, the incremental cost per patient cured on extending the eradication treatment from 7 to 10 days was euro147 (95% CI, 121.3-162.7), whereas in patients with functional or unexamined dyspepsia, it was -euro39.8 (95% CI, -28.5 to -60.7) and -euro27.3 (95% CI, -14.92 to -52.72), respectively. The sensitivity analysis showed that the efficacy of eradication treatment (7 vs 10) was the factor that most affected the stability of the results. CONCLUSIONS: Seven days is the most cost-effective duration of the triple therapy for eradicating H pylori in ulcer patients. However, 10 days is more cost-effective in functional dyspepsia patients or those with no prior endoscope diagnosis.

Gené E; Calvet X; Azagra R; Gisbert JP

2006-12-01

289

[Hand-foot syndrome induced by chemotherapy: a case study].  

UK PubMed Central (United Kingdom)

The study was aimed at reporting a case of a patient who developed Hand-Foot Syndrome (HFS) grade 3 due the use of capecitabine and for which massage was used with aqueous-based moisturizer, aloe vera. The patient's functional capacity was assessed using the ECOG Performance Scale and the lesions were photographed during nursing appointment that occurred at intervals of ten days, totaling forty days of monitoring. There was significant improvement in tissue integrity, with total regression of symptoms, an important gain in quality of life, and immediate return to chemotherapy. It is believed that aloe vera can be an important component in nursing care in patients undergoing cancer chemotherapy.

Simão DA; Lima ED; Souza RS; Faria TV; Azevedo GF

2012-03-01

290

Case Study: What Killed Leah Miller  

Science.gov (United States)

This is a case study for undergraduate students in anatomy and/or physiology. In particular this case study explores brain anatomy and physiology, hemostasis and blood clotting. Users of the National Center for Case Study Teaching in Science will be required to register (free) to gain access to the answer key (and must be of teaching status to receive the key). Included in the resource are the case overview, objectives, case study, teaching notes and answer key.

Sheri Boyce (Messiah College Biological Sciences)

2010-03-19

291

Ten-year absolute risk of osteoporotic fractures according to BMD T score at menopause: the Danish Osteoporosis Prevention Study  

DEFF Research Database (Denmark)

In the non-HRT arms of the DOPS study, 10-year fracture risk was higher at each level of T score than predicted by the Kanis algorithm. Under-reporting of fractures in registers and inclusion of HRT users are probable explanations for inappropriately low fracture risk estimates for younger women. INTRODUCTION: International recommendations highlight the importance of absolute fracture risk in establishing intervention thresholds. The available estimates of long-term risk have been derived by combining relative risks from meta-analyses with U.S. normative BMD data and Swedish fracture incidence records. We validated the 2001 Kanis risk algorithm using incident fractures observed in untreated women in the first 10 years of the Danish Osteoporosis Prevention Study (DOPS). Comparisons were also made with the relative risks derived from a recent meta-analysis of 12 cohort studies. MATERIALS AND METHODS: We analyzed DXA of the spine and hip from 872 women who were enrolled in the non-hormone replacement therapy (HRT) arms of the study and had not received HRT, bisphosphonates, or raloxifene. We collected verified reports of fractures at each visit. We focused on fractures of the hip, spine, shoulder, and forearm to provide risks comparable with the Kanis algorithm. Accordingly, asymptomatic radiographic vertebral fractures were not included. RESULTS: Seventy-eight women (9%) sustained relevant fractures. The risk of fracture increased by 1.32 (95% CI, 1.02; 1.70) for each unit decrease in femoral neck T score and by 1.30 (95% CI, 1.06; 1.58) for each unit decrease in lumbar spine T score at baseline. Absolute fracture risk was higher than expected from the Kanis algorithm at all T score levels. The difference was greatest for participants in the higher range of T scores. At T = -1, the observed risk was 10.9% as opposed to an expected risk of 5.7%. Relative risk gradients were similar to those of the recent meta-analysis. CONCLUSIONS: In healthy women, examined in the first year or two after menopause, 10-year fracture risk was higher at each level of BMD T score than expected from the model by Kanis et al. Inclusion of HRT users in the cohorts used may have led to higher BMD values and lower absolute fracture risk in the Kanis model. These longitudinal data can be used directly in estimating absolute fracture risk in untreated north European women from BMD at menopause.

Abrahamsen, Bo; Vestergaard, Peter

2006-01-01

292

Ten-year absolute risk of osteoporotic fractures according to BMD T score at menopause : the Danish Osteoporosis Prevention Study  

DEFF Research Database (Denmark)

In the non-HRT arms of the DOPS study, 10-year fracture risk was higher at each level of T score than predicted by the Kanis algorithm. Under-reporting of fractures in registers and inclusion of HRT users are probable explanations for inappropriately low fracture risk estimates for younger women. INTRODUCTION: International recommendations highlight the importance of absolute fracture risk in establishing intervention thresholds. The available estimates of long-term risk have been derived by combining relative risks from meta-analyses with U.S. normative BMD data and Swedish fracture incidence records. We validated the 2001 Kanis risk algorithm using incident fractures observed in untreated women in the first 10 years of the Danish Osteoporosis Prevention Study (DOPS). Comparisons were also made with the relative risks derived from a recent meta-analysis of 12 cohort studies. MATERIALS AND METHODS: We analyzed DXA of the spine and hip from 872 women who were enrolled in the non-hormone replacement therapy (HRT) arms of the study and had not received HRT, bisphosphonates, or raloxifene. We collected verified reports of fractures at each visit. We focused on fractures of the hip, spine, shoulder, and forearm to provide risks comparable with the Kanis algorithm. Accordingly, asymptomatic radiographic vertebral fractures were not included. RESULTS: Seventy-eight women (9%) sustained relevant fractures. The risk of fracture increased by 1.32 (95% CI, 1.02; 1.70) for each unit decrease in femoral neck T score and by 1.30 (95% CI, 1.06; 1.58) for each unit decrease in lumbar spine T score at baseline. Absolute fracture risk was higher than expected from the Kanis algorithm at all T score levels. The difference was greatest for participants in the higher range of T scores. At T = -1, the observed risk was 10.9% as opposed to an expected risk of 5.7%. Relative risk gradients were similar to those of the recent meta-analysis. CONCLUSIONS: In healthy women, examined in the first year or two after menopause, 10-year fracturerisk was higher at each level of BMD T score than expected from the model by Kanis et al. Inclusion of HRT users in the cohorts used may have led to higher BMD values and lower absolute fracture risk in the Kanis model. These longitudinal data can be used directly in estimating absolute fracture risk in untreated north European women from BMD at menopause.

Abrahamsen, Bo; Vestergaard, Peter

2006-01-01

293

CTLA-4 -1722T/C polymorphism and systemic lupus erythematosus susceptibility: a meta-analysis involving ten separate studies.  

UK PubMed Central (United Kingdom)

Cytotoxic T lymphocyte associated antigen-4 (CTLA-4) -1722T/C polymorphism has been identified as a susceptibile gene for systemic lupus erythematosus (SLE), but studies are inconsistent. To better assess the association between CTLA-4 -1722T/C polymorphism and SLE, a meta-analysis was performed, including 10 studies, total of 1 387 patients and 1 617 controls. Overall, the CTLA-4 -1722T/C polymorphism was significantly associated with SLE susceptibility (T VS C: OR = 1.17, 95% CI = 0.86-1.60, P = 0.304; T/T VS C/C: OR = 1.92, 95% CI = 1.09-3.39, P = 0.024; T/C VS C/C: OR = 1.50, 95% CI = 0.91-2.49, P = 0.114; T/T VS T/C: OR = 1.29, 95% CI = 0.95-1.75, P = 0.107). When stratified by ethnicity, the CTLA-4 -1722T/C polymorphism was associated with SLE only in Asians (T VS C: OR = 1.47, 95% CI = 1.10-1.96, P = 0.010; T/T VS C/C: OR = 2.09, 95% CI = 1.13-3.85, P = 0.018; T/C VS C/C: OR = 1.53, 95% CI = 0.87-2.69, P = 0.141; T/T VS T/C: OR = 1.42, 95% CI = 0.97-2.09, P = 0.070). In summary, the CTLA-4 -1722T/C polymorphism confers to SLE risk, especially in Asians.

Zhu JM; Li BK; Chen GM; Feng CC; Cen H; Fan YG; Wang B; Pan HF; Ye DQ

2013-01-01

294

Pragmatic Case Studies in Psychotherapy  

Science.gov (United States)

Started in 2005, the peer-reviewed, open-access journal Pragmatic Case Studies in Psychotherapy (PCSP) provides "innovative, quantitative and qualitative knowledge about psychotherapy process and outcome, for both researchers and practitioners." The publication is sponsored by the Rutgers University Graduate School of Applied and Professional Psychology, and first-time visitors can get a feel for their work by looking over the table of contents of the current issue on the right-hand side of their homepage. Visitors should also feel free to browse through the archives, register to receive the latest edition of PCSP via email, and also learn about their submission policies. Additionally, visitors can also sign up for their RSS feed and create their own collection of PCSP articles.

295

Pathology Case Study: Stillborn Fetus  

Science.gov (United States)

This is a case study presented by the University of Pittsburgh Department of Pathology which presents a 29 year old Hispanic woman who delivered a stillborn fetus with a estimated gestation of 29 weeks. Visitors are provided with patient history along with gross and microscopic descriptions, including images, and are given the opportunity to diagnose the patient. A "Final Diagnosis" section provides a discussion of the findings as well as references. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose disease. It is also a helpful site for educators to use to introduce or test student learning in perinatal pathology.

Klatt, Edward C., 1951-; Mccune, Ryan

2008-12-08

296

Pathology Case Study: Dog Bites  

Science.gov (United States)

This is a case study presented by the University of Pittsburgh Department of Pathology, which describes a 56-year-old male with a past medical history significant for lymphoma (in remission). The patient is a health care worker who presented to the emergency room because of a dog bite. Visitors are given a patient history and culture findings, including images. They are also given an opportunity to diagnose the patient before clicking on the "Final Diagnosis" section, which provides a discussion of the findings as well as references. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose disease. It is also a helpful site for educators to use to introduce or test student learning in clinical microbiology.

Pasculle, A. W.; Lourduraj, Leena T.; Iscoll, Eileen

2008-11-17

297

Solar Olympic village case study  

Energy Technology Data Exchange (ETDEWEB)

The Sydney 2000 Olympic Games incorporates an athlete's village which is part of a larger new residential development called Newington, aimed at creating a practical example of more sustainable living for the 21st century. Newington has a range of environmental features including solar hot water, solar photovoltaics, energy efficient design and water recycling for irrigation and toilets. Each home will have 1 kW (peak) of roof integrated PV connected to the grid via an inverter system. This paper presents a case study of the management, design, installation and testing of the solar village PV systems and also discusses related policy issues and requirements. The Newington development demonstrates that using today's technology a high concentration of solar power may be readily integrated into a residential development with benefits to all participants. However, work is needed to allow sustainable options to be made available to the mainstream market. (author)

Spooner, E.D.; Watt, M.E. [University of New South Wales, Sydney (Australia). Australian CRC for Renewable Energy; Morphett, D. [Pacific Power, Sydney (Australia); Grunwald, G. [Energy Australia, Sydney (Australia); Zacharias, P. [ISET Konigstor, Kassel (Germany)

2000-11-01

298

Enzyme replacement therapy in classical infantile pompe disease: results of a ten-month follow-up study.  

Science.gov (United States)

Infantile Pompe disease (IPD) is a fatal, autosomal recessive muscle-wasting disorder. Due to a deficiency of the lysosomal enzyme acid alpha-glucosidase patients develop a generalized myopathy, diaphragmatic weakness, and cardiomyopathy leading to death usually within the first year of life. So far there is no therapy available. We report on the safety and efficacy of transgenically derived recombinant human precursor acid alpha-glucosidase (rhGAA) in a 10-month follow-up study in two children with IPD who previously completed a 48-week course of enzyme replacement therapy (ERT) with the same medication at the same dose in a phase II clinical trial. Under this therapy cardiac status and muscle strength had improved, leading to survival beyond the age of one year. These results, together with data from two other phase II clinical trials encouraged further evaluation of the long-term safety and efficacy of enzyme replacement therapy in patients with infantile-onset Pompe disease. During the 10-month follow-up period, ERT was well-tolerated and neither patient experienced a single infusion-associated reaction. The initial improvements in cardiac size and function, as measured by left ventricular mass index and the fractional shortening, were maintained in both patients, and a continued improvement of motor function, as measured by the Alberta infant motor scale, was observed. PMID:15776317

Klinge, L; Straub, V; Neudorf, U; Voit, T

2005-02-01

299

Enzyme replacement therapy in classical infantile pompe disease: results of a ten-month follow-up study.  

UK PubMed Central (United Kingdom)

Infantile Pompe disease (IPD) is a fatal, autosomal recessive muscle-wasting disorder. Due to a deficiency of the lysosomal enzyme acid alpha-glucosidase patients develop a generalized myopathy, diaphragmatic weakness, and cardiomyopathy leading to death usually within the first year of life. So far there is no therapy available. We report on the safety and efficacy of transgenically derived recombinant human precursor acid alpha-glucosidase (rhGAA) in a 10-month follow-up study in two children with IPD who previously completed a 48-week course of enzyme replacement therapy (ERT) with the same medication at the same dose in a phase II clinical trial. Under this therapy cardiac status and muscle strength had improved, leading to survival beyond the age of one year. These results, together with data from two other phase II clinical trials encouraged further evaluation of the long-term safety and efficacy of enzyme replacement therapy in patients with infantile-onset Pompe disease. During the 10-month follow-up period, ERT was well-tolerated and neither patient experienced a single infusion-associated reaction. The initial improvements in cardiac size and function, as measured by left ventricular mass index and the fractional shortening, were maintained in both patients, and a continued improvement of motor function, as measured by the Alberta infant motor scale, was observed.

Klinge L; Straub V; Neudorf U; Voit T

2005-02-01

300

Ten-year viability study on natural populations of Drosophila sibling species from Laguna Verde, Veracruz, Mexico.  

UK PubMed Central (United Kingdom)

The generation of electricity in nuclear power plants produces an increase in background radiation that could possibly have some impact on the organisms that live in that area. In order to identify and quantify any such possible effect, the natural populations of two sibling species, D. melanogaster and D. simulans, that live in the immediate vicinity of the first Mexican Nuclear Power Plant were analyzed for a period of 10 years. Collections of flies were made at two sites, one close to and one farther from the power plant, during the pre and operational stages of the reactor, and their egg-to-adult viability was analyzed. The data obtained indicate that in both sites, the egg-to-adult viability was generally higher in D. melanogaster than in D. simulans. Further, a relationship was found between egg-to-adult viability and the season of the year (warm-wet or cool-dry season). Some differences were found between the two sites. It may be concluded that there is no negative impact on the Drosophila populations studied.

Pimentel E; Cruces MP; Salceda VM; de la Rosa ME; Levine L; Castillo JA

2004-02-01

 
 
 
 
301

A regional haemovigilance retrospective study of four types of therapeutic plasma in a ten-year survey period in France.  

UK PubMed Central (United Kingdom)

BACKGROUND AND OBJECTIVES: Our objective was to compare the frequency of adverse events (AEs) due to any of the 4 types of fresh-frozen plasma (FFP) prepared and delivered by the French Blood Establishment (EFS) over a 10-year period. Surveillance of AEs and vigilance was performed according to a homogeneous policy. The four types of FFP comprised of one type (methylene blue [MB) that was stopped since then and of another type [amotosalen (AI)] that was recently introduced, along with two conventional products [quarantine (Q) and solvent-detergent (SD)]. MATERIALS AND METHODS: This is a retrospective study based on the national AE reporting database and on the regional database system for deliveries. AEs recorded after the delivery of 1 of the 4 types of FFP were pairwise compared, with appropriate statistical corrections. RESULTS: 105,964 FFP units were delivered (38.4% Q, 17.9% SD, 9.7% MB and 34% AI). Statistical comparisons of AEs identified only a difference in AE rates between quarantine and solvent-detergent plasma. CONCLUSIONS: FFP was confirmed to be extremely safe in general, especially if one considers 'severe' AEs. All types of FFP were associated with extremely low occurrences of AEs. Q, SD, MB and AI led, respectively, to 7.14, 4.86, 1.05 and 4.16 AEs per 10,000 deliveries.

Bost V; Odent-Malaure H; Chavarin P; Benamara H; Fabrigli P; Garraud O

2013-05-01

302

The association of microalbuminuria with mortality in patients with acute myocardial infarction. A ten-year follow-up study  

Directory of Open Access Journals (Sweden)

Full Text Available Our study evaluates the long-term effect of microalbuminuria on mortality among patients with acute myocardial infarction. We followed 151 patients from 1996 to 2007 to investigate if microalbuminuria is a risk factor in coronary heart disease. All patients admitted with acute myocardial infarction in 1996 were included. At baseline, we recorded urinary albumin/creatinine concentration ratio, body mass index, blood pressure, left ventricle ejection fraction by echocardiography, smoking status, medication, diabetes, age, and gender. Deaths were traced in 2007 by means of the Danish Personal Identification Register. Microalbuminuria, defined as a urinary albumin/creatinine concentration ratio above 0.65 mg/mmoL, occurred in 50% of the patients and was associated with increased all-cause mortality. Thus, 68% of the patients with microalbuminuria versus 48% of the patients without microalbuminuria had died during the 10 years of follow-up (P=0.04). The crude hazard ratio for death associated with microalbuminuria was 1.78 (CI: 1.18-2.68) (P=0.006), whereas the gender- and age-adjusted hazard ratio was 1.71 (CI: 1.03-2.83) (P=0.04). We concluded that microalbuminuria in hospitalized patients with acute myocardial infarction is prognostic for increased long-term mortality. We recommend measurement of microalbuminuria to be included as a baseline risk factor in patients with acute myocardial infarction and in future trials in patients with cor-onary heart disease.

Mustafa Taskiran; Allan Iversen; Klaus Klausen; Gorm B. Jensen; Jan Skov Jensen

2010-01-01

303

The association of microalbuminuria with mortality in patients with acute myocardial infarction. A ten-year follow-up study  

DEFF Research Database (Denmark)

Our study evaluates the long-term effect of microalbuminuria on mortality among patients with acute myocardial infarction. We followed 151 patients from 1996 to 2007 to investigate if microalbuminuria is a risk factor in coronary heart disease. All patients admitted with acute myocardial infarction in 1996 were included. At baseline, we recorded urinary albumin/creatinine concentration ratio, body mass index, blood pressure, left ventricle ejection fraction by echocardiography, smoking status, medication, diabetes, age, and gender. Deaths were traced in 2007 by means of the Danish Personal Identification Register. Microalbuminuria, defined as a urinary albumin/creatinine concentration ratio above 0.65 mg/mmoL, occurred in 50% of the patients and was associated with increased all-cause mortality. Thus, 68% of the patients with microalbuminuria versus 48% of the patients without microalbuminuria had died during the 10 years of follow-up (P=0.04). The crude hazard ratio for death associated with microalbuminuriawas 1.78 (CI: 1.18-2.68) (P=0.006), whereas the gender- and age-adjusted hazard ratio was 1.71 (CI: 1.03-2.83) (P=0.04). We concluded that microalbuminuria in hospitalized patients with acute myocardial infarction is prognostic for increased long-term mortality. We recommend measurement of microalbuminuria to be included as a baseline risk factor in patients with acute myocardial infarction and in future trials in patients with coronary heart disease.

Taskiran, Mustafa; Iversen, Allan

2010-01-01

304

Executive functioning in schizophrenia spectrum disorder patients and their unaffected siblings: a ten-year follow-up study.  

UK PubMed Central (United Kingdom)

Executive dysfunction represents a core deficit that is associated with schizophrenia spectrum disorders (SSDs). However, the longitudinal course of executive deficits in SSDs is still controversial. The aim of this study was to examine the executive performance of 34 SSD patients in relation to 34 of their unaffected siblings over a period of 10 years. Both groups completed psychopathological and executive assessments. Thirteen healthy controls were assessed using the same instruments. At baseline, the SSD patients differed significantly from siblings and controls in their performance on the Trail Making Test-B (TMT-B) and the number of categories in which they succeeded in the Wisconsin Card Sorting Test (WCST). They also differed significantly from the controls in the total number of errors in the WCST. The siblings did not differ in executive functioning from the controls over the follow-up. Longitudinally, the patients demonstrated significant improvement only for the TMT-B. However, only 14.71% of the patients showed reliable and clinically significant improvements for the TMT-B, and 8.82% made more errors on the WCST at the follow-up evaluation. Less than 3% of the patients showed either improved or worse results on the remaining measures of the WCST. A stabilisation pattern for the WCST was observed in the three groups. The patients performed worse than their siblings and controls on both executive tests. Some patients exhibited significant improvements in the TMT-B over time, but this improvement was reliable and clinically significant for less than 15% of the sample. Thus, we conclude that the patients exhibited stable impairments over time in the executive functions assessed.

Sánchez-Torres AM; Basterra V; Moreno-Izco L; Rosa A; Fañanás L; Zarzuela A; Peralta V; Cuesta MJ

2013-02-01

305

NWCC Transmission Case Study III  

Energy Technology Data Exchange (ETDEWEB)

OAK-B135 Transmission System Improvements for Wind Energy Development in the Upper Midwest and Great Plains: Opportunities and Obstacles. This case study set out to ascertain the validity of three assumptions from the perspectives of stakeholders involved in wind energy and transmission issues in the Upper Midwest and Great Plains. The assumptions, and the stakeholders' reactions to each, are summarized below: Assumption 1--Transmission system improvements would provide significant benefits to the electricity network and its customers. Respondents acknowledge the potential for overall system benefits in the form of reduced line losses, improved grid stability and reliability, and enhanced ability to conduct spot market transactions. They also agree that these benefits relate to specific regional needs. However, there is disagreement over the extent of other benefits such as efficiency gains and cost savings from reduced line losses. Further, environmental and community interest groups point out that none of these benefits are realized without significant financial, environmental and social costs. Assumption 2--The benefits of transmission improvements would be helpful, but not confined, to wind power. All respondents agree that wind energy could benefit from transmission system improvements. But they also acknowledge, reluctantly, in the case of environmental stakeholders, that the benefits of an improved transmission system cannot be limited to environmentally preferable forms of generation. Some environmental and community advocate respondents also feel that transmission system improvement projects can be avoided altogether through energy conservation and efficiency measures, and by substituting wind energy for fossil generation. Assumption 3--Transmission alliances among stakeholders within and external to the wind community can provide benefits in the public interest. The fractured, multi-jurisdictional governance of the regional transmission system, and the distrust and diversity of perspectives among affected stakeholders, may make the formation of multi-stakeholder alliances necessary to accomplishing transmission goals. If the wind industry and utilities want to partner with environmental and community advocate groups in supporting a transmission project, they may have to convince these groups that the project would result in a net environmental benefit. The project proponents would have to make the case that the benefits of the additional wind energy will at least offset the emissions of any additional fossil generation made possible by the transmission project, as well as offset the environmental impact of the transmission project itself.

Terry Allison, Steve Wiese

2000-03-01

306

Ten Questions about Emergence  

CERN Multimedia

Self-Organization is of growing importance for large distributed computing systems. In these systems, a central control and manual management is exceedingly difficult or even impossible. Emergence is widely recognized as the core principle behind self-organization. Therefore the idea to use both principles to control and organize large-scale distributed systems is very attractive and not so far off. Yet there are many open questions about emergence and self-organization, ranging from a clear definition and scientific understanding to the possible applications in engineering and technology, including the limitations of both concepts. Self-organizing systems with emergent properties are highly desirable, but also very challenging. We pose ten central questions about emergence, give preliminary answers, and identify four basic limits of self-organization: a size limit, a place limit, a complexity limit and finally a combinatorial limit.

Fromm, J

2005-01-01

307

Meningite bacteriana neonatal agentes etiológicos em 109 casos durante período de dez anos/ Raterial meningitis in newborn infants: etiologic agents in 109 cases throughout ten years  

Scientific Electronic Library Online (English)

Full Text Available Abstract in portuguese A etiologia das meningites purulentas foi analisada em 109 recém-nascidos admitidos em unidade de cuidados intensivos neonatais durante período de dez anos. Bactérias foram recuperadas do LCR de 57 (52,2%) recém-nascidos. Verificou-se predomínio dos bacilos Gram-negativos isolados em 38 (34,9%); cocos Gram-positivos foram isolados em somente 12 (11,0%). Os microorganismos tidos como de contaminação hospitalar - Klebsiella sp, Salmonella sp, Enterobacter sp, Pseudom (more) onas sp, Flavobacterium meningosepticum e Ser-ratia marcescens responderam pela etiologia presumível em 38 (49,3%) dentre 77 pacientes com culturas positivas; foram isolados de 22 (7,0%) recém-nascidos com procedência hospitalar imediata e somente em 12 (34,3%) daqueles vindos diretamente do domicílio (X2 = 4,08; p Abstract in english The etiology of purulent meningitis was investigated in 109 newborn infants admitted in a neonatal intensive care unit throughout a ten year period. Bacterial pathogens were isolated from the CSF in 57 (52.2%) neonates. There was a predominance of Gram-negative bacilli isolated in 38 (34.9%) neonates. Gram-positive cocci were isolated from CSF in only 12 (11.0%) neonates. Microorganisms associated with nosocomial septicemia and meningitis in neonates - Klebsiella sp, Salm (more) onella sp, Enterobacter sp, Pseudomonas sp, Flavobacterium meningosepticum and Sematia marcescens - were responsible for presumptive etiology in 38 (49.3%) among 77 patients with positive cultures in "closed sites". They were isolated from 22 (57.0%) neonates with prior hospitalization but only from 12 (34.3%) neonates coming directly from their households (X2==4.08; p

Ramos, Sonia R. T. Silva; Feferbaum, Rubens; Manissadjian, Antranik; Vaz, Flávio A. Costa

1992-09-01

308

[Plasma cell leukemia. Study of 10 cases  

UK PubMed Central (United Kingdom)

Ten patients with plasma cell leukaemia (PCL), out of 259 cases of multiple myeloma diagnosed in the Haematology Service of the University Hospital of Barcelona in the last 18 years, are presented. Of the 10 PCL cases, 5 were primary and 5 were secondary. Anaemia and thrombocytopenia, along with massive plasma cell infiltration of the bone marrow, were the most striking findings. Osteolytic lesions were present in 9 of the cases and liver involvement in two. Chemotherapy including vincristine and prednisone was administered to eight patients, associated to alkylating agents (melphalan and/or cyclophosphamide) in six of them. Four of these patients received also adriamycin and BCNU. Two objective responses were achieved, lasting for 10 and 3 months, the remaining six patients failed to respond. The median survival for all the PCL patients was less than one month (ranging between 0.2 and 14 months). None of the secondary PCL patients survived for 2 months after diagnosis. Infection (3 cases of septicaemia and 3 of pneumonia), renal failure (2 cases) and liver insufficiency (1 case) were the causes of death in the nine deceased patients. The therapeutic possibilities for this severe haemopathy are discussed.

López Guillermo A; Martí JM; Bladé J; Nomdedeu B; Montserrat E; Rozman C

1989-02-01

309

"Clicker" Cases: Introducing Case Study Teaching Into Large Classrooms  

Science.gov (United States)

Case study teaching is difficult in large classes, especially in fixed-seat ampitheaters. The development of audience response systems, or "clickers," for use in classrooms has opened up exciting new possibilities for creating and implementing interactive case studies, particularly in large introductory science courses.

Freeman-Herreid, Clyde

2006-10-01

310

Innovative and Alternative Technology: Case Studies.  

Science.gov (United States)

This report provides case studies of eleven projects which have received additional grant funds through the Innovative and Alterative (I/A) Program. The purpose of this report is to present information gathered during investigation of eleven case studies.

D. J. Hinrichs N. E. Heim J. A. Faisst B. E. Burris

1981-01-01

311

Identification of high-risk individuals for the development of disability in activities of daily living. A ten-year follow-up study.  

UK PubMed Central (United Kingdom)

Independence in activities of daily living (ADL) is important in an aging population. ADL disability is a multifactorial problem, therefore a multifactorial approach is needed in the prediction of ADL disability. Our objective is to identify predictors for the development of ADL disability over a course of ten years in middle-aged and older persons. In a prospective cohort study, 478 middle-aged and older persons (61.2 years, range 40-78 years) without ADL disability at baseline were included. ADL disability was measured using the Katz-questionnaire. We included the following candidate predictors: number of chronic diseases, MMSE, Short Physical Performance Battery, leg strength, handgrip strength, physical activity, cholesterol/HDL ratio, BMI, pulse wave velocity, the degree of urbanization, age, gender and socioeconomic status. Associations between candidate predictors and ADL disability were examined using Poisson regression analysis. Performance of the prediction model was assessed with calibration and discrimination measures. The number of chronic diseases, muscle strength, age, gender and socioeconomic status were predictors of ADL disability at ten-year follow-up. The model showed a good calibration and discrimination (c-statistic: 0.83) between persons who will and will not develop ADL disability. In conclusion, the present study showed that using a multifactorial prediction model - based on easily and readily available measurements - individuals who are at high risk of developing ADL disability could be identified. The prediction model could be used as a screening tool to identify which persons most likely benefit from preventive strategies and interventions.

den Ouden ME; Schuurmans MJ; Mueller-Schotte S; van der Schouw YT

2013-04-01

312

Energy-motivation case study  

Energy Technology Data Exchange (ETDEWEB)

Most energy-management case studies focus on capital investments in new technical equipment, such as more-efficient boilers, lighting systems or computerised energy-management systems. The wide range of technical options for saving energy are well documented and advertised. Another aspect of energy management - namely the achievement of 'no cost' or 'good housekeeping' measures through well-organised motivation and incentive campaigns - is not so well reported. This is due to there being few examples of this type of project, which itself probably reflects the energy managers' preferences for dealing with 'hard' engineering rather than 'soft' people-orientated issues. This paper documents the development and implementation of a motivation campaign for the Social Services Department of Coventy City Council which was novel for two reasons: first, it is believed to be the first motivation campaign in a Social Services department; and secondly, it involved the use of training, incentives and feedback in an integrated way that it is believed greatly boosted its effectiveness. (author).

Fawkes, S. (Energy Partnership Ltd., London (GB)); Bratley, J. (P.A. Consulting Group, London (GB))

1989-01-01

313

Five misunderstandings about Case-study Research  

DEFF Research Database (Denmark)

This article examines five common misunderstandings about case-study research: (1) Theoretical knowledge is more valuable than practical knowledge; (2) One cannot generalize from a single case, therefore the single case study cannot contribute to scientific development; (3) The case study is most useful for generating hypotheses, while other methods aremore suitable for hypotheses testing and theory building; (4) The case study contains a bias toward verification; and (5) It is often difficult to summarize specific case studies. The article explains and corrects these misunderstandings one by one and concludes with the Kuhnian insight that a scientific discipline without a large number of thoroughly executed case studies is a discipline without systematic production of exemplars, and that a discipline without  exemplars is an ineffective one. Social science may be strengthened by the execution of more good case studies.

Flyvbjerg, Bent

2004-01-01

314

Case Study: The Chemistry of Cocaine  

Science.gov (United States)

|This column provides original articles on innovations in case study teaching, assessment of the method, as well as case studies with teaching notes. This month's case study focuses on the chemistry of cocaine to teach a number of core concepts in organic chemistry. It also requires that students read and analyze an original research paper on…

Dewprashad, Brahmadeo

2011-01-01

315

Ten principles of good interdisciplinary team work.  

UK PubMed Central (United Kingdom)

BACKGROUND: Interdisciplinary team work is increasingly prevalent, supported by policies and practices that bring care closer to the patient and challenge traditional professional boundaries. To date, there has been a great deal of emphasis on the processes of team work, and in some cases, outcomes. METHOD: This study draws on two sources of knowledge to identify the attributes of a good interdisciplinary team; a published systematic review of the literature on interdisciplinary team work, and the perceptions of over 253 staff from 11 community rehabilitation and intermediate care teams in the UK. These data sources were merged using qualitative content analysis to arrive at a framework that identifies characteristics and proposes ten competencies that support effective interdisciplinary team work. RESULTS: Ten characteristics underpinning effective interdisciplinary team work were identified: positive leadership and management attributes; communication strategies and structures; personal rewards, training and development; appropriate resources and procedures; appropriate skill mix; supportive team climate; individual characteristics that support interdisciplinary team work; clarity of vision; quality and outcomes of care; and respecting and understanding roles. CONCLUSIONS: We propose competency statements that an effective interdisciplinary team functioning at a high level should demonstrate.

Nancarrow SA; Booth A; Ariss S; Smith T; Enderby P; Roots A

2013-01-01

316

Blacks in the Big Ten  

Science.gov (United States)

Focuses on the concern of three black administrators in a Big Ten" university about the plight of black athletes in the Big Ten Athletic Conference--their problems, their failure to complete formal education, and their lack of representation at all levels in Big Ten employment, particularly in coaching and officiating. (SB)

Green, Robert L.; And Others

1972-01-01

317

Primary colorectal small cell carcinoma: A clinicopathological and immunohistochemical study of 10 cases  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Colorectal small cell carcinoma (SmCC) is a rare tumor with an aggressive course. The aim of this study is to summarize our experience with this tumor and to highlight its immunohistochemical profile. Ten cases of colorectal SmCC were identified in our files and a panel of immunostains was performed...

El Demellawy, Dina; Khalifa, Mahmoud A; Ismiil, Nadia; Wong, Shun; Ghorab, Zeina

318

TenTen: A New Array of Multi-TeV Imaging Cherenkov Telescopes  

CERN Multimedia

The exciting results from H.E.S.S. point to a new population of gamma-ray sources at energies E > 10 TeV, paving the way for future studies and new discoveries in the multi-TeV energy range. Connected with these energies is the search for sources of PeV cosmic-rays (CRs) and the study of multi-TeV gamma-ray production in a growing number of astrophysical environments. TenTen is a proposed stereoscopic array (with a suggested site in Australia) of modest-sized (10 to 30m^2) Cherenkov imaging telescopes with a wide field of view (8 to 10deg diameter) optimised for the E~10 to 100 TeV range. TenTen will achieve an effective area of ~10 km^2 at energies above 10 TeV. We outline here the motivation for TenTen and summarise key performance parameters.

Rowell, G; Clay, R; Dawson, B; Denman, J; Protheroe, R; Smith, A G K; Thornton, G; Wild, N

2007-01-01

319

Transanal rectopexy - twelve case studies  

Directory of Open Access Journals (Sweden)

Full Text Available OBJECTIVES: This study analyzed the results of transanal rectopexy and showed the benefits of this surgical technique. METHOD: Twelve patients were submitted to rectopexy between 1997 and 2011. The surgical technique used was transanal rectopexy, where the mesorectum was fixed to the sacrum with nonabsorbable suture. Three patients had been submitted to previous surgery, two by the Delorme technique and one by the Thiersch technique. RESULTS: Postoperative hospital stay ranged from 1 to 4 days. One patient (8.3%) had intraoperative hematoma, which was treated with local compression and antibiotics. One patient (8.3%) had residual mucosal prolapse, which was resected. Prolapse recurrence was seen in one case (8.3%). Improved incontinence occurred in 75% of patients and one patient reported obstructed evacuation in the first month after surgery. No death occurred. CONCLUSION: Transanal rectopexy is a simple, low cost technique, which has shown good efficacy in rectal prolapse control.OBJETIVO: O presente estudo analisou os resultados da retopexia pela via transanal e expôs os benefícios desta técnica cirúrgica. MÉTODO: Doze pacientes com prolapso foram operados no período de 1997 a 2011. A técnica cirúrgica usada foi a retopexia transanal, onde o mesorreto foi fixado ao sacro com fio inabsorvível. Três pacientes tinham cirurgia prévia, dois pela técnica de Delorme e um pela técnica de Thiersch. RESULTADOS: A permanência hospitalar pós-operatória variou de 1- 4 dias. Uma paciente (8,3%) apresentou hematoma transoperatório que foi tratado com compressão local e antibioticoterapia. Um paciente apresentou prolapso mucoso residual (8,3%), que foi ressecado. Houve recidiva da procidência em um caso (8,3%). A melhora da incontinência ocorreu em 75% dos pacientes e uma paciente apresentou bloqueio evacuatório no primeiro mês após a cirurgia. Não houve mortalidade entre os pacientes operados. CONCLUSÃO: A retopexia transanal é uma técnica simples, de baixo custo e apresentou boa eficácia no controle do prolapso retal.

Rubens Henrique Oleques Fernandes; Tito Armando Rossi

2012-01-01

320

Hospital facilities management: Case study  

Energy Technology Data Exchange (ETDEWEB)

The process of energy management at the Mayo Foundation Rochester is a multifaceted process involving several divisions and Mayo Foundation Committees. This gives several opportunities to impact the energy consumption of a given building. The processes used are: (1) Facilities Engineering Services: The design and construction are the responsibility of another division and input is sought from operations to optimize the energy efficiency of the building systems during that process. (2) Operations Energy Management: After a building is placed on-line, the systems to be operated and maintained become the responsibility of the Operations Division. (3) Energy Conservation Measurements: A number of energy audits were performed using data from the energy management team to establish the opportunities in each major building. From that list, projects with a simple payback of five years or less are brought forward to funding committees for consideration. (4) Infrastructure Analysis: A team of Facilities Operations and Facilities Engineering staff developed a needs list for each building that is a part of the nearly 10,000,000 square feet owned by Mayo in Rochester, Minnesota. This list was prioritized by, one, life safety needs; two, maintenance needs; and three, economics payback opportunities. (5) Strategic Planning: After a building has been in service for many years, evaluation of the use of the building and its systems yields an opportunity for change that may reduce energy consumption. For the purposes of this case study, only the following elements of energy conservation at Mayo will be reviewed, namely, the impact of the Operation Energy Management Team, and the infrastructure analysis process.

Olson, R.W. [Mayo Clinic, Rochester, NM (United States)

1996-12-31

 
 
 
 
321

Ten-year incidence rates of age-related cataract in the Age-Related Eye Disease Study (AREDS): AREDS report no. 33.  

UK PubMed Central (United Kingdom)

PURPOSE: To investigate the long-term incidence of age-related cataract and cataract surgery in the Age-Related Eye Disease Study (AREDS) cohort. METHODS: Baseline and annual lens photographs of participants, aged 55-80 years, were graded centrally for nuclear, cortical, and posterior subcapsular (PSC) lens opacities using the AREDS System for Classifying Cataracts. Progression from a baseline status of no or mild lens opacity to at least moderate severity was analyzed and cumulative incidence estimated rates were calculated for each lens opacity type and cataract surgery stratified by age, sex, race, age-related macular degeneration category, multivitamin (Centrum) use and history of diabetes. RESULTS: The ten-year cumulative incidence was 43.6% for any cataract, 23.1% for nuclear cataract, 22.0% for cortical cataract, 13.1% for PSC cataract, and 26.8% for cataract surgery. The 5- and 10-year incidence rates of all cataract types and cataract surgery were significantly higher with increasing age. Females had a higher incidence of any, nuclear and cortical cataract and cataract surgery (p?=?0.02-0.05). Incidence of cortical cataract was higher in non-white participants (p?=?0.001). CONCLUSIONS: These results are largely consistent with the results of previous observational studies. Long-term incidence rates of type-specific cataract can be useful in designing clinical studies of age-related cataract.

Koo E; Chang JR; Agrón E; Clemons TE; Sperduto RD; Ferris FL 3rd; Chew EY

2013-04-01

322

Giant adrenal cyst: case study  

Digital Repository Infrastructure Vision for European Research (DRIVER)

One of the rarest situations regarding an adrenal incidentaloma is an adrenal cyst. We present the case of a 61Z–year old male patient diagnosed with peritonitis. During surgery, a right adrenal tumor of 2 cm is discovered. The patient was referred to endocrinology. 6 months later the diameter of th...

Poiana, C; Carsote, M; Chirita, P; Terzea, D; Paun, S; Beuran, M

323

The case for case studies: Optimising the use of communication cases  

Directory of Open Access Journals (Sweden)

Full Text Available Case studies are widely used by communication and public relations practitioners and educators. Yet, despite their extensive use, the question should be asked whether public relations case studies are applied in the best possible way. Many tertiary education institutions are moving away from case study analysis as a discrete subject and instead adopting a ‘case study approach’ across the communication curriculum. This paper explores the merits of different styles of the case method and the reference materials available, and concludes that formalised analysis of case studies is essential to fully optimise their application.

Tony Jaques

2009-01-01

324

Ten steps or climbing a mountain: A study of Australian health professionals' perceptions of implementing the baby friendly health initiative to protect, promote and support breastfeeding  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background The Baby Friendly Hospital (Health) Initiative (BFHI) is a global initiative aimed at protecting, promoting and supporting breastfeeding and is based on the ten steps to successful breastfeeding. Worldwide, over 20,000 health facilities have attained BFHI accreditation but only 77 Australian hospitals (approximately 23%) have received accreditation. Few studies have investigated the factors that facilitate or hinder implementation of BFHI but it is acknowledged this is a major undertaking requiring strategic planning and change management throughout an institution. This paper examines the perceptions of BFHI held by midwives and nurses working in one Area Health Service in NSW, Australia. Methods The study used an interpretive, qualitative approach. A total of 132 health professionals, working across four maternity units, two neonatal intensive care units and related community services, participated in 10 focus groups. Data were analysed using thematic analysis. Results Three main themes were identified: 'Belief and Commitment'; 'Interpreting BFHI' and 'Climbing a Mountain'. Participants considered the BFHI implementation a high priority; an essential set of practices that would have positive benefits for babies and mothers both locally and globally as well as for health professionals. It was considered achievable but would take commitment and hard work to overcome the numerous challenges including a number of organisational constraints. There were, however, differing interpretations of what was required to attain BFHI accreditation with the potential that misinterpretation could hinder implementation. A model described by Greenhalgh and colleagues on adoption of innovation is drawn on to interpret the findings. Conclusion Despite strong support for BFHI, the principles of this global strategy are interpreted differently by health professionals and further education and accurate information is required. It may be that the current processes used to disseminate and implement BFHI need to be reviewed. The findings suggest that there is a contradiction between the broad philosophical stance and best practice approach of this global strategy and the tendency for health professionals to focus on the ten steps as a set of tasks or a checklist to be accomplished. The perceived procedural approach to implementation may be contributing to lower rates of breastfeeding continuation.

Schmied Virginia; Gribble Karleen; Sheehan Athena; Taylor Christine; Dykes Fiona C

2011-01-01

325

Case study: Group load curtailment  

Energy Technology Data Exchange (ETDEWEB)

This article is a slide show discussion of demand-side management efforts by San Diego Gas and Electric as applied to a particular industry in their service area. The evolution of SDG&E`s rate structure is noted, from interruptible services rates to the present structure of variable time-of-use. For the case noted, this has resulted in a reduction of outages at the manufacturing facility and a 30% reduction in the cost per kwh to the user.

Linn, D.

1995-12-31

326

[Leucinosis: study of a case  

UK PubMed Central (United Kingdom)

Report of a case of Maple syrup urine disease in a female neonate, with diagnosis at 26th day of life. The neurological picture consisted of alternating periods of hyper with hypotonicity, seizures, lethargy, poor feeding and respiratory arrest. Demonstration of elevation of plasma branched-chain amino-acids, was the most widely available confirmatory test, and the therapy with MSUD resulted in improvement of the patient.

Moura-Ribeiro MV; Funayama CA

1985-12-01

327

Use of 3D-computed tomography angiography for planning the surgical removal of pineal region meningiomas using Poppen's approach: a report of ten cases and a literature review  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background There are several treatment approaches for pineal region meningiomas, such as Poppen's approach, Krause's approach and combinations of the two approaches. We present our experience with the use of 3D-computed tomography angiography for planning the surgical removal of pineal region meningiomas using a suboccipital transtentorial approach (Poppen's approach) and evaluate the role of Poppen's approach. Methods During the period from January 2005 to June 2010, ten patients presented to us with pineal region meningioma. MRI was routinely used to define the tumor size, position, and its relevant complications while 3D-CTA was applied to define the blood supply of the tumor and the venous complex (VC) shift before operations. Most of the meningiomas had developed at both sides of the tentorial plane and extended laterally with typical characteristics of a pineal region tumor. Results All tumors were completely removed surgically without any injury to the VC. Postoperative intracranial infection occurred in one case who recovered after antibiotics were given. Postoperative intraventricular hemorrhage and pneumocephalus were found in one case, but fully recovered after conservative treatment. In the nine cases of concurrent hydrocephalus, this was gradually relieved in eight patients and the single case that became aggravated was successfully treated with ventriculoperitoneal shunt. Moreover, the follow-up MRI examinations did not indicate any recurrence of the meningiomas. Conclusion We found that the use of Poppen's approach is strongly supported for the successful removal of pineal region meningiomas without serious complications.

Li Yunqian; Zhao Gang; Wang Honglei; Zhu Wanan; Qu Limei; Li Ye; Yu Jinlu

2011-01-01

328

[Preiser's disease. A case study].  

UK PubMed Central (United Kingdom)

The idiopathic avascular necrosis of the scaphoid or Preiser's disease is condition about which few cases have been described. In the majority of cases, it is debatable whether it is actually a spontaneous osteonecrosis, or a pathological process secondary to a systematic disease, or a result of chemotherapy treatment, or associated with taking steroids. We present the case of a 20-year old woman, with no previous trauma, with pain in her right wrist, which progressed over a period of four years. It was wrongly diagnosed as a tendinitis, and was treated conservatively without any improvement. A simple X-ray was requested that showed an abnormality of the proximal pole of the scaphoid that was beginning to fragment; a fact which was confirmed later by performing a CT scan. This was followed by nuclear magnetic resonance spectroscopy (NMR), which showed signs of ischaemia, mainly in the proximal pole. There were signs of viability in the distal fragment in the NMR using paramagnetic contrast. After the imaging tests, idiopathic avascular necrosis of the scaphoid was diagnosed. The surgical treatment consisted of the removal of necrotic fragments of the proximal pole and removal of the posterior interosseous-nerve. Two years after the intervention, the patient is asymptomatic and with a complete range of movement in the operated wrist.

Andrés Grau J; Sarabia Condés JM; Gil Gómez JE; Carrillo Juliá FJ; Abellán Guillén JF

2013-01-01

329

Study on Case Teaching of Financial Management  

Directory of Open Access Journals (Sweden)

Full Text Available Case teaching is an efficient teaching method of management. It plays an important role to enhance the students’ ability to practice the theory. However, case teaching of financial management has not achieved the expected results. The paper aims to study the importance, characteristics and corresponding methods of case teaching method of financial management.

Zhenghong Che; Zhengmei Che

2011-01-01

330

The Wirtgen surface miner - two case studies  

Energy Technology Data Exchange (ETDEWEB)

This paper contains two case studies which illustrate the use of Wirtgen continuous surface miners. Case 1 is about gypsum mining in South Africa, while case 2 is concerned with production performance trials of a Wirtgen 3000 SM in a surface coal mine in Western Australia. The design, operation, operating conditions, and performance of the miners are described. 1 ref., 4 figs., 1 tab.

Buesching, R.

1988-08-01

331

Enhancing Ethnic Diversity at a Big Ten University through Project TEAM: A Case Study in Teacher Education.  

Science.gov (United States)

Describes the development of Project Transformative Educational Achievement Model (TEAM), an instructional initiative intended to increase the numbers of diverse students at Indiana University who enter teacher education, graduate, and obtain teaching licensure in Indiana. Data from interviews, meta-comment papers, and student transcripts focus on…

Bennett, Christine I.

2002-01-01

332

Composites in manufacturing - Case studies  

Energy Technology Data Exchange (ETDEWEB)

The papers presented in this volume focus on 19 cases of applied technology in composites design and manufacturing, all of them dealing with specific products. Topics covered include design using composite in aerospace, innovative materials and processing, tooling, fasteners and adhesives, finishing, repair, specialty applications of composites, and applications in the automotive industry. Papers are presented on the filament winding of isogrid fuselage structures; design and use of aramid fiber in aircraft structures; resin transfer molding of a complex composite aircraft structure; and field repair of an advanced helicopter vertical fin structure.

Strong, A.B. (Brigham Young University, Provo, UT (United States))

1991-01-01

333

Hemangioma racemoso de retina (síndrome de Wyburn-Mason): acompanhamento de um paciente por dez anos: relato de caso/ Retinal racemose hemangioma (Wyburn-Mason syndrome): a patient ten years follow-up: case report  

Scientific Electronic Library Online (English)

Full Text Available Abstract in portuguese Relatar o caso de um paciente que apresentou hemangioma racemoso de retina (síndrome de Wyburn-Mason) e seu acompanhamento por 10 anos. Dez anos após o diagnóstico da doença o exame oftalmológico não sofreu alterações, assim como o campo visual e a retinografia. O prognóstico a longo prazo é controverso. Alguns autores relatam estabilidade das lesões oculares, como no caso descrito, enquanto outros referem perda progressiva da visão. Abstract in english To describe the case of a patient who presents retinal racemose hemangioma (Wyburn-Mason syndrome) and his 10 years follow-up. Ten years after the disease diagnosis, the ophthalmologic exam had no changes, as well as the campimetry and the retinography. The long term prognosis is controversial. Some authors report ocular lesions stability and others report progressive visual loss.

Leitão Guerra, RL; Leitão Guerra, CL; Guerra, M; Guerra Neto, AS; Leitão Guerra, AA

2009-08-01

334

The Chernobyl nuclear power station accident, ten years after. International cooperative study on the assessment of health effects by Belarus, Russia and Ukraine, and Japan  

Energy Technology Data Exchange (ETDEWEB)

Nearly ten years have passed since the happening of the chernobyl Nuclear Power Station Accident. The former, Soviet Union has started various researches in cooperation with the neighboring countries and U.S.A. The outcomes of such researches have been published on the biological effects by the radioactive exposure due to the accident. The cooperation of our country with the Union did not so smoothly progress to quickly start cooperative research on the accident. However, international researches between both countries have started in non-governmental levels at last after many complications including the changes in the political system of the former Soviet Union. The assessment of the biological effects by the radiation is largely depending on the results from further investigations. Especially, it is thought that valuable informations would be obtained by studies in respect of the effects of radiation exposure at low doses and low dose rates. On a basis of various experiences obtained from these cooperative researches the way to cooperate in future international researches was discussed. (M.N.)

Uchiyama, Masashi [National Inst. of Radiological Sciences, Chiba (Japan); Nagaoka, Toshi; Yamashita, Shunichi [and others

1996-03-01

335

Comparative study of the therapeutic effect of a systemic analgesic and transcutaneous electrical nerve stimulation (TENS) on post-IMF trismus and pain in Nigerian patients.  

UK PubMed Central (United Kingdom)

OBJECTIVES: To compare the therapeutic effect of paracetamol and Transcutaneous Electrical Nerve Stimulation (TENS), on post-Intermaxillary Fixation (IMF) trismus, and pain in some Nigerian patients. PATIENTS AND METHODS: Twenty patients treated for mandibular fractures with IMF were randomly selected into two groups of ten patients each. After the release of IMF, they were started on jaw exercises with the aid of wooden spatulae to overcome trismus due to muscle spasm. Patients in Group I underwent jaw exercises before and after TENS therapy which lasted for 30 minutes while those in Group II had jaw exercises before and 30 minutes after ingestion of 100 mg of paracetamol. Their inter-incisal distances were recorded pre and post intervention. RESULTS: Analysis of the data showed that for both therapeutic interventions, there was an appreciable gain in mouth-opening which was more prominent for patients with unusual difficulty in mouth-opening initially. However, a comparison between the mean improvements produced by TENS and analgesic revealed no significant difference between the two groups. CONCLUSION: Both the TENS therapy and paracetamol provided similarly appreciable differences in inter-incisal distances (mouth-opening) after their applications.

Fagade OO; Oginni FO; Obilade TO

2005-06-01

336

Giant adrenal cyst: case study.  

UK PubMed Central (United Kingdom)

One of the rarest situations regarding an adrenal incidentaloma is an adrenal cyst. We present the case of a 61-year-old male patient diagnosed with peritonitis. During surgery, a right adrenal tumor of 2 cm is discovered. The patient was referred to endocrinology. 6 months later the diameter of the tumor is 7 times bigger than the initial stage. It has no secretory phenotype, except for the small increase of serum aldosterone and the 24-h 17-ketosteroids. Open right adrenalectomy is performed and a cyst of 15 cm is removed. The evolution after surgery is good. The pathological exam reveals an adrenal cyst with calcifications and osteoid metaplasia. The immunohistochemistry showed a positive reaction for CD34 and ACT in the vessels and VIM in the stroma. The adrenal cysts are not frequent and represent a challenge regarding the preoperative diagnostic and surgical procedure of resection. The pathological exam highlights the major aspects.

Poiana C; Carsote M; Chirita C; Terzea D; Paun S; Beuran M

2010-07-01

337

String universality in ten dimensions.  

UK PubMed Central (United Kingdom)

We show that the N=1 supergravity theories in ten dimensions with gauge groups U(1){496} and E{8}×U(1){248} are not consistent quantum theories. Cancellation of anomalies cannot be made compatible with supersymmetry and Abelian gauge invariance. Thus, in ten dimensions all supersymmetric theories of gravity without known inconsistencies are realized in string theory.

Adams A; Taylor W; Dewolfe O

2010-08-01

338

Case Study on Logistics Performance  

Digital Repository Infrastructure Vision for European Research (DRIVER)

The paper presents research carried out at a medium?size manufacturing organization in east Asia. The study tries to highlight the importance of supply chain management; specifically, our aim for this study is to understand logistics and performance measurement in the logistics and supply chain, and...

Shahryar Sorooshian; Manimekalai Jambulingam; Javad Dodangeh

339

The effect of ill health and socioeconomic status on labor force exit and re-employment: a prospective study with ten years follow-up in the Netherlands.  

UK PubMed Central (United Kingdom)

OBJECTIVES: The aim of this study was to investigate the effect of ill health and socioeconomic status on labor force exit due to unemployment, early retirement, disability pension, or becoming economically inactive. A secondary objective was to investigate the effect of ill health and socioeconomic status on return to work. METHODS: A representative sample of the Dutch working population (N=15 152) was selected for a prospective study with ten years follow-up (93 917 person-years). Perceived health and individual and household characteristics were measured at baseline with the Permanent Quality of Life Survey (POLS) during 1999-2002. Statistics Netherlands ascertained employment status monthly from January 1999 to December 2008. Cox proportional hazards analyses were used to determine the factors that predicted labor force exit and return to work. RESULTS: Ill health increased the likelihood of labor force exit into unemployment [hazard ratio (HR) 1.89], disability pension (HR 6.39), and early retirement (HR 1.20), but was not a determinant of becoming economically inactive (HR 1.07). Workers with low socioeconomic status were, even after adjusting for ill health, more likely to leave the labor force due to unemployment, disability pension, and economic inactivity. Workers with ill health at baseline were less likely to return to work after unemployment (HR 0.75) or disability pension (HR 0.62). Socioeconomic status did not influence re-employment. CONCLUSIONS: Ill health is an important determinant for entering and maintaining paid employment. Workers with lower education were at increased risk for health-based selection out of paid employment. Policies to improve labor force participation, especially among low socioeconomic level workers, should protect workers with health problems against exclusion from the labor force.

Schuring M; Robroek SJ; Otten FW; Arts CH; Burdorf A

2013-03-01

340

Regional case studies--Africa.  

UK PubMed Central (United Kingdom)

Africa is the final continent to be affected by the nutrition transition and, as elsewhere, is characterized by the paradoxical coexistence of malnutrition and obesity. Several features of the obesity epidemic in Africa mirror those in other emerging nations: it penetrates the richer nations and urban areas first with a strong urban- rural gradient; initially it affects the wealthy, but later there is a demographic switch as obesity becomes a condition more associated with poverty, and it shares many of the same drivers related to the increasing affordability of highly refined oils and carbohydrates, and a move away from subsistence farm work and towards sedentary lifestyles. Africa also has some characteristics of the obesity epidemic that stand out from other regions such as: (1) excepting some areas of the Pacific, Africa is probably the only region in which obesity (especially among women) is viewed culturally as a positive and desirable trait, leading to major gender differences in obesity rates in many countries; (2) most of Africa has very low rates of obesity in children, and to date African obesity is mostly an adult syndrome; (3) Africans seem genetically prone to higher rates of diabetes and hypertension in association with obesity than Caucasians, but seem to be relatively protected from dislipidemias; (4) the case-specific deaths and disabilities from diabetes and hypertension in Africa are very high due to the paucity of health services and the strain that the 'double burden' of disease places on health systems.

Prentice AM

2009-01-01

 
 
 
 
341

Leishmaniasis in dogs: Case study  

Directory of Open Access Journals (Sweden)

Full Text Available The paper presents a case of leishmaniasis in a 2.5-month-old dog imported from France. The clinical examination established a generally poor state of health, expressed cachexia, atrophy of the temporal musculature, weakness of movement, as well as abnormally long and brittle nails. There was also hyperkeratosis of the nose tip and paws. A histological examination of biopsy sections of the altered skin parts showed inflammatory changes in the area of the dermis, together with infiltration of macrophages and a smaller number of lymphocytes, plasmocytes and neutrophil granulocytes in the area around the sebaceous glands and hair follicles. The determined changes correspond to superficial dermatitis. Edema followed by partial degeneration of connective-tissue fibers is observed in connective tissue. A smaller number of intracellular parasitic forms was established in mononuclear cells. A smaller number of oval amastigotes with round dark red nucleis were observed in sections stained using the Gimza method in the cytoplasm of macrophages located in the dermis, but also extracellularly. It was concluded that the dog was diseased with leishmaniasis on the grounds of the clinical picture and the microscopic findings.

Aleksi? Jelena; Kukolj Vladimir; Popovi? Nikola

2009-01-01

342

Music in context : Four case studies  

Digital Repository Infrastructure Vision for European Research (DRIVER)

In his thesis entitled “Music in Context. Four Case Studies”, R.J.C. van Randwijck investigates the context in which music has been created. It is a search in Four Case Studies, approaching four pieces of music from the context in which they were written in order to understand their meaning. The inv...

Randwijck, Rutger Jules Cornelis van

343

Case Study: A Strategic Research Methodology  

Digital Repository Infrastructure Vision for European Research (DRIVER)

This research reviews the literature on case study as a strategic qualitative research methodology. Although case studies have been criticised by some authors as lacking scientific rigour and do not address generalizability, this research, however, reiterated its appropriateness when dealing with a ...

Khairul B.M. Noor

344

NAVAIR Information Technology Case Study.  

Science.gov (United States)

This study employed an online survey (with 126 respondents) to investigate variables affecting job satisfaction levels and feelings regarding the NAVAIR IT procurement process among Naval Air Warfare Center Weapons Division (NAWCWD) China Lake end users. ...

K. P. Tajii

2010-01-01

345

Are nested case-control studies biased?  

UK PubMed Central (United Kingdom)

It has been recently asserted that the nested case-control study design, in which case-control sets are sampled from cohort risk sets, can introduce bias ("study design bias") when there are lagged exposures. The bases for this claim include a theoretical and an "empirical evaluation" argument. We examined both of these arguments and found them to be incorrect. We describe an appropriate empirical evaluation method to explore the performance of nested case-control study designs and analysis methods from an existing cohort. This empirical evaluation approach relies on simulating case-control outcomes from risk sets in the cohort from which the case-control study is to be performed. Because it is based on the underlying cohort structure, the empirical evaluation can provide an assessment that is tailored to the specific characteristics of the study under consideration. The methods are illustrated using samples from the Colorado Plateau uranium miners cohort.

Langholz B; Richardson D

2009-05-01

346

Outage management: A case study  

Energy Technology Data Exchange (ETDEWEB)

Outage management issues identified from a field study conducted at a two-unit commercial pressurized water reactor (PWR), when one unit was in a refueling outage and the other unit was at full power operation, are the focus of this paper. The study was conduced as part of the US Nuclear Regulatory Commission's (NRC) organizational factors research program, and therefore the issues to be addressed are from an organizational perspective. Topics discussed refer to areas identified by the NRC as critical for safety during shutdown operations, including outage planning and control, personnel stress, and improvements in training and procedures. Specifically, issues in communication, management attention, involvement and oversight, administrative processes, organizational culture, and human resources relevant to each of the areas are highlighted by example from field data collection. Insights regarding future guidance in these areas are presented based upon additional data collection subsequent to the original study.

Haber, S.B.; Barriere, M.T. (Brookhaven National Lab., Upton, NY (United States)); Roberts, K.H. (California Univ., Berkeley, CA (United States). Walter A. Haas School of Business)

1992-01-01

347

Outage management: A case study  

Energy Technology Data Exchange (ETDEWEB)

Outage management issues identified from a field study conducted at a two-unit commercial pressurized water reactor (PWR), when one unit was in a refueling outage and the other unit was at full power operation, are the focus of this paper. The study was conduced as part of the US Nuclear Regulatory Commission`s (NRC) organizational factors research program, and therefore the issues to be addressed are from an organizational perspective. Topics discussed refer to areas identified by the NRC as critical for safety during shutdown operations, including outage planning and control, personnel stress, and improvements in training and procedures. Specifically, issues in communication, management attention, involvement and oversight, administrative processes, organizational culture, and human resources relevant to each of the areas are highlighted by example from field data collection. Insights regarding future guidance in these areas are presented based upon additional data collection subsequent to the original study.

Haber, S.B.; Barriere, M.T. [Brookhaven National Lab., Upton, NY (United States); Roberts, K.H. [California Univ., Berkeley, CA (United States). Walter A. Haas School of Business

1992-09-01

348

Outage management: A case study  

International Nuclear Information System (INIS)

[en] Outage management issues identified from a field study conducted at a two-unit commercial pressurized water reactor (PWR), when one unit was in a refueling outage and the other unit was at full power operation, are the focus of this paper. The study was conduced as part of the US Nuclear Regulatory Commission's (NRC) organizational factors research program, and therefore the issues to be addressed are from an organizational perspective. Topics discussed refer to areas identified by the NRC as critical for safety during shutdown operations, including outage planning and control, personnel stress, and improvements in training and procedures. Specifically, issues in communication, management attention, involvement and oversight, administrative processes, organizational culture, and human resources relevant to each of the areas are highlighted by example from field data collection. Insights regarding future guidance in these areas are presented based upon additional data collection subsequent to the original study

1992-01-01

349

Case studies for transcriptional profiling.  

UK PubMed Central (United Kingdom)

DNA microarrays are frequently used to study transcriptome regulation in a wide variety of organisms. Although they are an invaluable tool for the acquisition of large scale dataset in plant systems biology, a number of surprising results and unanticipated complications are often encountered that illustrate the limitations and potential pitfalls of this technology. In this chapter we will present examples of real world studies from two classes of microarray experiments that were designed to (i) identify target genes for transcriptional regulators and (ii) to characterize complex expression patterns to reveal unexpected dependencies within transcriptional networks.

Hennig L; Köhler C

2007-01-01

350

Oral cancer: a retrospective study of 100 Danish cases  

DEFF Research Database (Denmark)

One hundred Danes with oral cancer who were collected consecutively from 1986 to 1991 were evaluated retrospectively. The study included subjective and objective observations in 56% men and in 44% women. M:F ratio was 1.2:1. Fifty percent of the patients were non-smokers. Nine percent were women who did not drink alcohol. Ten percent of the patients were between 40 and 49 years of age, 20% between 50 and 59 years, 35% were between 60 and 69 years and 20% between 70 and 79 years of age. This may reflect a tradition of early drinking and smoking. Doctor's delay was the cause of delayed referral in 14% of the cases while 72% of the patients were the cause themselves for the delayed referral.

Pinholt, E M; Rindum, J

1997-01-01

351

Ten-day sequential therapy is more effective than proton pump inhibitor-based therapy in Korea: a prospective, randomized study.  

UK PubMed Central (United Kingdom)

BACKGROUND AND AIMS: The eradication rate of proton pump inhibitor (PPI)-based triple therapy for Helicobacter pylori (H. pylori) infection has decreased, mainly due to increasing antibiotic resistance, especially against clarithromycin. It has been reported that a 10-day sequential strategy can produce good outcomes. The aim of this prospective study was to assess the efficacy of sequential therapy as the first-line treatment for the eradication of H. pylori in Korea. METHODS: A total of 116 patients with proven H. pylori infection received 10-day sequential therapy (20 mg rabeprazole and 1 g amoxicillin, twice daily for the first 5 days, followed by 20 mg rabeprazole, 500 mg clarithromycin, and 500 mg metronidazole, twice daily for the remaining 5 days); 130 patients received 7-day triple therapy (20 mg rabeprazole, 500 mg clarithromycin, and 1 g amoxicillin, twice daily for 7 days). Eradication was evaluated by the (13) C-urea breath test, 4 weeks after the completion of treatment. Compliance and adverse events were assessed. RESULTS: The eradication rates of 10-day sequential therapy and PPI-based triple therapy were 79.3% (92/116) and 63% (82/130) by intention-to-treat analysis, respectively (P = 0.005), and 81.9% (91/111) and 64.5% (82/127) by per protocol analysis, respectively (P = 0.003). Mild adverse events occurred in both therapy groups (27.5% vs 23.8%), but both treatments were well tolerated. CONCLUSION: The eradication rate of the 10-day sequential therapy regimen was significantly higher than that of PPI-based triple therapy in the Korean population. Ten-day sequential therapy might be effective as a first-line treatment for H. pylori infection in Korea.

Oh HS; Lee DH; Seo JY; Cho YR; Kim N; Jeoung SH; Kim JW; Hwang JH; Park YS; Lee SH; Shin CM; Cho HJ; Jung HC; Song IS

2012-03-01

352

Center manifold: A case study  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Following Almgren's construction of the center manifold in his Big regularity paper, we show the C(3,alpha) regularity of area-minimizing currents in the neighborhood of points of density one without using the nonparametric theory. This study is intended as a first step towards the understanding of ...

De Lellis, C; Spadaro, E

353

Center Manifold: a case study  

CERN Multimedia

Following Almgren's construction of the "center manifold" in his Big regularity paper, we show the C^{3,\\alpha} regularity of area-minimizing currents in the neighborhood of points of density one without using the nonparametric theory. This study is intended as a first step towards the understanding of Almgren's construction in its full generality.

De Lellis, Camillo

2011-01-01

354

[Uterine rupture in pregnancy--case study].  

UK PubMed Central (United Kingdom)

OBJECTIVE: Analysis of two cases uterine rupture following caesarian section. SUBJECT: Two case studies. SETTING: Gynecological obstetrics clinic, First Medical Faculty and Faculty Hospital Bulovka, Prague. SUBJECT AND METHODS: The authors in their article describe two cases of rupture of the uterus in pregnancy prior to delivery. In both cases there was a history of cervicocorporal caesarian section. CONCLUSION: In the first case the patient was admitted from her home with bleeding, and signed a nonconsent form. The second case concerned a hospitalized patient, in which the first signs of uterine rupture were indicated by fetal heart rate. Both women underwent hysterectomy, paradoxically, in the first case the child was saved and discharged home in good health.

Záhumenský J; Brtnická H; Brtnický T; Sottner O; Zmrhalová B; Halaska M

2010-08-01

355

Labyrinthine sequestrum: four case studies.  

UK PubMed Central (United Kingdom)

Labyrinthine sequestrum, a rare form of labyrinthitis, is highly distinct from the more commonly encountered labyrinthitis ossificans based on its unique clinical, radiologic, and histologic characteristics. The study included 4 such patients who had undergone clinical and laboratory investigations, computed tomography (CT), and magnetic resonance imaging (MRI) assessments followed by surgical procedures and pathological evaluation. Their major symptoms were otorrhea, otalgia, tinnitus, and profound hearing loss. Imaging studies showed an osteolytic soft mass with calcified debris in the inner ear, and the bony labyrinth was eroded partly or completely by granulation mass, with loss of bony morphology. Further pathological examination was coincident with inflammatory granulation tissue with some calcification or osseous tissue. The disease process is attributed to chronic osteomyelitis due to the presence of osteonecrosis. Prompt CT and MRI examinations and optimal therapeutic management facilitate definitive diagnosis and protect against fatal complications.

Lao Z; Sha Y; Chen B; Dai CF; Huang WH; Cheng YS

2012-09-01

356

Labyrinthine sequestrum: four case studies.  

Science.gov (United States)

Labyrinthine sequestrum, a rare form of labyrinthitis, is highly distinct from the more commonly encountered labyrinthitis ossificans based on its unique clinical, radiologic, and histologic characteristics. The study included 4 such patients who had undergone clinical and laboratory investigations, computed tomography (CT), and magnetic resonance imaging (MRI) assessments followed by surgical procedures and pathological evaluation. Their major symptoms were otorrhea, otalgia, tinnitus, and profound hearing loss. Imaging studies showed an osteolytic soft mass with calcified debris in the inner ear, and the bony labyrinth was eroded partly or completely by granulation mass, with loss of bony morphology. Further pathological examination was coincident with inflammatory granulation tissue with some calcification or osseous tissue. The disease process is attributed to chronic osteomyelitis due to the presence of osteonecrosis. Prompt CT and MRI examinations and optimal therapeutic management facilitate definitive diagnosis and protect against fatal complications. PMID:22467283

Lao, Zheng; Sha, Yan; Chen, Bing; Dai, Chun-Fu; Huang, Wen-Hu; Cheng, Yu-Shu

2012-03-30

357

Arctic bioremediation -- A case study  

Energy Technology Data Exchange (ETDEWEB)

This paper discusses the use of bioremediation as an effective method to clean up diesel-range hydrocarbon spills in northern latitudes. The results of a laboratory study of microbial degradation of hydrocarbons under simulated arctic conditions showed that bioremediation can be effective in cold climates and led to the implementation of a large-scale field program. The results of 3 years of field testing have led to a significant reduction in diesel-range hydrocarbon concentrations in the contaminated area.

Smallbeck, D.R.; Ramert, P.C. (Harding Lawson Associates, Novato, CA (United States)); Liddell, B.V.

1994-05-01

358

Disseminated granuloma annulare: study on eight cases.  

Science.gov (United States)

Granuloma annulare (GA) is classified as localized, generalized/disseminated, subcutaneous, and perforating types. The studies show connection with diabetes mellitus, lipidic metabolic disorders, malignant diseases, thyroid disorders, infections (HBV, HCV, HIV). We performed a retrospective study between 2010-2011, regarding disseminated GA (GAD), and the relationship between GAD and other comorbidities. We clinically and histologically diagnosed eight cases of GAD. The patients were also investigated for the diagnosis of associated diseases. The treatment included topical corticosteroids, antihistamines, Calcipotriol/Betamethasone, Tacrolimus 0.03%, Pentoxifylline, Hydroxychloroquine. Therapeutic response was assessed one month and three months after hospitalization. Our patients were five women and three men, aged 46-68 years, mean age 57.25 years, with a disease history of one year and a half (between three months and four years). The lesions occurred in the upper extremities (eight cases), distal extremities (three cases), cervical area (two cases), and trunk (five cases). In seven cases, we found annular appearance and one patient had disseminated small papules eruption. Associated pathology was diabetes mellitus type II (five cases), overweight and obesity (five cases), dyslipidemia (three cases), hypothyroidism (one case), rheumatoid arthritis (one case), external ear canal basal carcinoma (one case). Although there is controversy regarding the relationship between GAD and associated diseases, it is accepted that it is significantly associated with diabetes mellitus, also found in our study in five out of eight cases. We noticed obvious improvements after local and general treatment. It is confirmed that GAD is prevalent in women, over 40-year-old. GAD is often associated with diabetes and dyslipidemia, therefore it is necessary to investigate patients in this direction. The histopathological exam is essential for an accurate confirmation of GA. PMID:23771077

P?tra?cu, V; Giurc?, Claudia; Ciurea, Raluca Niculina; Georgescu, Claudia Valentina

2013-01-01

359

Disseminated granuloma annulare: study on eight cases.  

UK PubMed Central (United Kingdom)

Granuloma annulare (GA) is classified as localized, generalized/disseminated, subcutaneous, and perforating types. The studies show connection with diabetes mellitus, lipidic metabolic disorders, malignant diseases, thyroid disorders, infections (HBV, HCV, HIV). We performed a retrospective study between 2010-2011, regarding disseminated GA (GAD), and the relationship between GAD and other comorbidities. We clinically and histologically diagnosed eight cases of GAD. The patients were also investigated for the diagnosis of associated diseases. The treatment included topical corticosteroids, antihistamines, Calcipotriol/Betamethasone, Tacrolimus 0.03%, Pentoxifylline, Hydroxychloroquine. Therapeutic response was assessed one month and three months after hospitalization. Our patients were five women and three men, aged 46-68 years, mean age 57.25 years, with a disease history of one year and a half (between three months and four years). The lesions occurred in the upper extremities (eight cases), distal extremities (three cases), cervical area (two cases), and trunk (five cases). In seven cases, we found annular appearance and one patient had disseminated small papules eruption. Associated pathology was diabetes mellitus type II (five cases), overweight and obesity (five cases), dyslipidemia (three cases), hypothyroidism (one case), rheumatoid arthritis (one case), external ear canal basal carcinoma (one case). Although there is controversy regarding the relationship between GAD and associated diseases, it is accepted that it is significantly associated with diabetes mellitus, also found in our study in five out of eight cases. We noticed obvious improvements after local and general treatment. It is confirmed that GAD is prevalent in women, over 40-year-old. GAD is often associated with diabetes and dyslipidemia, therefore it is necessary to investigate patients in this direction. The histopathological exam is essential for an accurate confirmation of GA.

P?tra?cu V; Giurc? C; Ciurea RN; Georgescu CV

2013-01-01

360

Physical functioning is related to both an impaired physical ability and ADL disability: a ten year follow-up study in middle-aged and older persons.  

UK PubMed Central (United Kingdom)

OBJECTIVE: Identification of measures of physical function that mediate or link impaired physical ability with disability in activities of daily living (ADL) is necessary to facilitate the development of interventions to prevent or delay the onset of ADL disability. We examined whether measures of physical function at baseline are determinants of the Short Physical Performance Battery, as measure of physical ability, and disability, at ten years follow-up. STUDY DESIGN: Prospective cohort study in 625 middle-aged and older persons. MAIN OUTCOME MEASURES: Physical ability was measured by Guralniks Short Physical Performance Battery (impaired physical ability: score <6) and ADL ability by the KATZ questionnaire (ADL disability: score ? 1). Physical function was measured by lung function (in men only), handgrip strength, leg strength, and physical activity. The associations between physical function and the dichotomized impaired physical ability and disability-score were estimated using Poisson regression. RESULTS: Better lung function and higher leg strength were associated with a lower risk of having impaired physical ability, RR=0.98, 95% CI [0.96; 0.99] per 10 L/min and RR=0.97, 95% CI [0.94; 0.99] per 10Nm, respectively. Higher handgrip strength, leg strength and level of physical activity were associated with a lower risk of having ADL disability, RR=0.72, 95% CI [0.57; 0.92] per 10 kg, RR=0.95, 95% CI [0.92; 0.98] per 10Nm, RR=0.98, 95% CI [0.96; 0.99] per point-score, respectively. Additional adjustment for baseline ADL disability did not materially changed the point-estimates (except for handgrip strength). CONCLUSION: Overall, leg extensor strength was associated with both an impaired physical ability and ADL disability. Other measures of physical functioning were either related to an impaired physical ability or ADL disability. ADL disability may be an intermediate factor for hand grip strength in the causal chain from impaired physical ability to ADL disability at follow-up. The results of this study show that leg strength might be a relevant parameter to consider for future intervention studies.

den Ouden ME; Schuurmans MJ; Brand JS; Arts IE; Mueller-Schotte S; van der Schouw YT

2013-01-01

 
 
 
 
361

A Comparison Between the Carbon Fiber Cage and the Cloward Procedure in Cervical Spine Surgery A Ten- to Thirteen-Year Follow-Up of a Prospective Randomized Study  

Digital Repository Infrastructure Vision for European Research (DRIVER)

Study Design. Ten- to 13-year follow-up of a prospective randomized study. Objective. To compare the 10- to 13-year outcomes of anterior cervical decompression and fusion (ACDF) with a cervical intervertebral fusion cage (CIFC), and the Cloward procedure (CP) using a broad clinical and patient-cente...

Hermansen, Anna; Hedlund, Rune; Vavruch, Ludek; Peolsson, Anneli

362

Frequency and antimicrobial resistance patterns of bacteria implicated in community urinary tract infections: a ten-year surveillance study (2000–2009)  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background Urinary tract infection (UTI) is one of the most common infectious diseases at the community level. In order to assess the adequacy of the empirical therapy, the prevalence and the resistance pattern of the main bacteria responsible for UTI in the community (in Aveiro, Portugal) was evaluated throughout a ten-year period. Methods In this retrospective study, all urine samples from patients of the District of Aveiro, in ambulatory regime, collected at the Clinical Analysis Laboratory Avelab during the period 2000–2009 were analysed. Samples with more than 105 CFU/mL bacteria were considered positive and, for these samples, the bacteria were identified and the profile of antibiotic susceptibility was characterized. Results From the 155597 samples analysed, 18797 (12.1%) were positive for bacterial infection. UTI was more frequent in women (78.5%) and its incidence varied with age, affecting more the elderly patients (38.6%). Although E. coli was, as usual, the most common pathogen implicated in UTI, it were observed differences related to the other bacteria more implicated in UTI relatively to previous studies. The bacteria implicated in the UTI varied with the sex of the patient, being P. aeruginosa a more important cause of infection in men than in women. The incidence of the main bacteria changed over the study period (P. aeruginosa, Klebsiella spp and Providencia spp increased and Enterobacter spp decreased). Although E. coli was responsible for more than an half of UTI, its resistance to antibiotics was low when compared with other pathogens implicated in UTI, showing also the lowest percentage of multidrug resistant (MDR) isolates (17%). Bacteria isolated from females were less resistant than those isolated from males and this difference increased with the patient age. Conclusions The differences in sex and age must be taken into account at the moment of empirical prescription of antimicrobials. From the recommended antimicrobials by the European Association of Urology guidelines, the first line drugs (pivmecillinam and nitrofurantoin) and the alternative antibiotic amoxicillin-clavulanic acid (AMX-CLA) are appropriate to treat community-acquired UTI, but the fluoroquinolones should not be suitable to treat male infections and the trimethoprim-sulfamethoxazole (SXT) shall not be used in the treatment of UTI at this level.

Linhares Inês; Raposo Teresa; Rodrigues António; Almeida Adelaide

2013-01-01

363

Frequency and antimicrobial resistance patterns of bacteria implicated in community urinary tract infections: a ten-year surveillance study (2000-2009).  

UK PubMed Central (United Kingdom)

BACKGROUND: Urinary tract infection (UTI) is one of the most common infectious diseases at the community level. In order to assess the adequacy of the empirical therapy, the prevalence and the resistance pattern of the main bacteria responsible for UTI in the community (in Aveiro, Portugal) was evaluated throughout a ten-year period. METHODS: In this retrospective study, all urine samples from patients of the District of Aveiro, in ambulatory regime, collected at the Clinical Analysis Laboratory Avelab during the period 2000-2009 were analysed. Samples with more than 105 CFU/mL bacteria were considered positive and, for these samples, the bacteria were identified and the profile of antibiotic susceptibility was characterized. RESULTS: From the 155597 samples analysed, 18797 (12.1%) were positive for bacterial infection. UTI was more frequent in women (78.5%) and its incidence varied with age, affecting more the elderly patients (38.6%). Although E. coli was, as usual, the most common pathogen implicated in UTI, it were observed differences related to the other bacteria more implicated in UTI relatively to previous studies. The bacteria implicated in the UTI varied with the sex of the patient, being P. aeruginosa a more important cause of infection in men than in women. The incidence of the main bacteria changed over the study period (P. aeruginosa, Klebsiella spp and Providencia spp increased and Enterobacter spp decreased). Although E. coli was responsible for more than an half of UTI, its resistance to antibiotics was low when compared with other pathogens implicated in UTI, showing also the lowest percentage of multidrug resistant (MDR) isolates (17%). Bacteria isolated from females were less resistant than those isolated from males and this difference increased with the patient age. CONCLUSIONS: The differences in sex and age must be taken into account at the moment of empirical prescription of antimicrobials. From the recommended antimicrobials by the European Association of Urology guidelines, the first line drugs (pivmecillinam and nitrofurantoin) and the alternative antibiotic amoxicillin-clavulanic acid (AMX-CLA) are appropriate to treat community-acquired UTI, but the fluoroquinolones should not be suitable to treat male infections and the trimethoprim-sulfamethoxazole (SXT) shall not be used in the treatment of UTI at this level.

Linhares I; Raposo T; Rodrigues A; Almeida A

2013-01-01

364

Energy Audit: A Case Study  

Directory of Open Access Journals (Sweden)

Full Text Available This India is the Fifth largest producer of Electricalenergy in the world. Despite such achievements the gapbetween demand and supply of electrical energy is increasingevery year and power sector is highly capital – intensive. Thusthe deficit in installed capacity was nearly 10000MWper year.So the gap between demand and supply is continuouslyincreasing day by day. An energy audit is a study of a plant orfacility to determine how and where energy is used and toidentify methods for energy savings. The opportunities lie inthe use of existing renewable energy technologies, greaterefforts at energy efficiency and the dissemination of thesetechnologies and options. This thesis provides an overview of ageneral energy conservation measures (ECMs) that can becommonly recommended for NIT Hamirpur. It should be notedthat the Energy auidut presented in this paper does not pretendto be exhaustive nor comprehensive. It provides merely toindicate some of the options that energy auditor can considerwhen performing an analysis of this institute. Energyconservation and exploration of new energy avenues are thewell accepted solution to fulfil the demand in future. The totalcost of energy plays a vital role in determining the product costof a commodity. Therefore the identification of potential energysavings and implementation for a given institutional facility isunimportant to ensure its competitive advantage over otherinstitute. This paper work presents such energy saving methodsin a methodological approach, experienced during a detailedenergy audit of NIT Hamirpur.

Sanjay Kumar; Tarlochan Kaur

2013-01-01

365

Antiphospholipid syndrome: A case study  

Energy Technology Data Exchange (ETDEWEB)

Full text: A forty-two-year-old male presented to the Royal Adelaide Hospital with symptoms of increasing shortness of breath, swelling in both ankles, petechial rash and blood in his sputum. Initial investigations showed cardiomegaly, right ventricular hypertrophy, patchy lung infiltrates, a platelet count of 1500 and a clotting time of 60 seconds. A V/Q scan indicated a high probability of pulmonary embolism. Further investigations showed that the patient was positive for lupus anticoagulant and cardiolipin antibodies. A diagnosis of primary antiphospholipid syndrome was made. The patient``s high risk of strokes and hemorrhaging prompted investigation by a {sup 99}mTc-HMPAO brain scan. Further V/Q scans were performed to follow up the initial finding of multiple pulmonary embolism and a R-L shunt study was performed to investigate a left subclavian murmur. The patient was admitted for four weeks and began treatment which included cyclaphosphamide, corticosteroids and plasmaphoresis and was discharged when stable. Over the next six months he was re admitted three times for relapse of antiphospholipid syndrome. On his fourth admission he collapsed and died five hours after admission. Cause of death was due to cardiac arrhythmia secondary to severe right ventricular hypertrophy and dilation. The effects of antiphospholipid syndrome was believed to be responsible for this outcome.

Davies, T. [Royal Adelaide Hospital, Adelaide, SA (Australia). Department of Nuclear Medicine

1998-03-01

366

Antiphospholipid syndrome: A case study  

International Nuclear Information System (INIS)

Full text: A forty-two-year-old male presented to the Royal Adelaide Hospital with symptoms of increasing shortness of breath, swelling in both ankles, petechial rash and blood in his sputum. Initial investigations showed cardiomegaly, right ventricular hypertrophy, patchy lung infiltrates, a platelet count of 1500 and a clotting time of 60 seconds. A V/Q scan indicated a high probability of pulmonary embolism. Further investigations showed that the patient was positive for lupus anticoagulant and cardiolipin antibodies. A diagnosis of primary antiphospholipid syndrome was made. The patient''s high risk of strokes and hemorrhaging prompted investigation by a 99mTc-HMPAO brain scan. Further V/Q scans were performed to follow up the initial finding of multiple pulmonary embolism and a R-L shunt study was performed to investigate a left subclavian murmur. The patient was admitted for four weeks and began treatment which included cyclaphosphamide, corticosteroids and plasmaphoresis and was discharged when stable. Over the next six months he was re admitted three times for relapse of antiphospholipid syndrome. On his fourth admission he collapsed and died five hours after admission. Cause of death was due to cardiac arrhythmia secondary to severe right ventricular hypertrophy and dilation. The effects of antiphospholipid syndrome was believed to be responsible for this outcome.

1998-01-01

367

Case studies of steel structure failures  

Directory of Open Access Journals (Sweden)

Full Text Available The contribution deals with some case studies of steel structure failures, which happened in Slovakia a few years ago. Features of cracking are illustrated on real cases of breakdowns in the transmission gas pipelines, at the cement works and in the petrochemical indus-try. All failures were caused by an incorrect technical approach. Possible remedial measures are proposed.

P. Bernasovský

2010-01-01

368

Dez anos de experiência com cirurgia micrográfica pelo método de Munique: relato de 93 casos operados A ten-year experience with the Munich method of micrographic surgery: a report of 93 operated cases  

Directory of Open Access Journals (Sweden)

Full Text Available FUNDAMENTOS: A cirurgia de Mohs é um dos métodos mais eficazes de tratamento dos carcinomas basocelulares. A expansão de seus conceitos possibilitou o surgimento de outros métodos de checagem de margens cirúrgicas igualmente eficazes. O método de Munique é um exemplo disso. OBJETIVOS: Avaliar a eficácia da cirurgia micrográfica pelo método de Munique em um estudo de coorte com 10 anos de duração. MÉTODOS: 93 pacientes com 96 tumores cutâneos foram tratados com cirurgia micrográfica pelo método de Munique, participando de um protocolo de acompanhamento, no período de maio de 1994 a julho de 2004. RESULTADOS: 61,4% dos tumores eram recidivados; 42,3% eram recidivados mais de uma vez; 53% eram do tipo esclerodermiforme. A média do maior diâmetro dos tumores foi de 1,58cm e do menor 1,10cm. Em 95% dos casos se obteve a extirpação total do tumor, com até três estágios. A localização mais comum foi a nasal (46,3%), seguida da periocular (18,9%) e da frontal (11,5%). Perdeu-se o contato apenas com dois pacientes. Dos 96 tumores operados, apenas 11 têm tempo de seguimento inferior a dois anos. 56 pacientes foram seguidos por pelo menos cinco anos, e 45 (47,3%), por mais de seis anos. Apenas um caso de recidiva foi verificado, tendo ocorrido no sexto ano de observação. CONCLUSÃO: O método de Munique é um método eficiente de cirurgia micrográfica, tanto quanto o método de Mohs. Este trabalho fornece mais um indício de que o conceito de cirurgia micrográfica deve ser ampliado para cirurgia microscopicamente controlada, e não ficar ligado estritamente ao termo cirurgia de Mohs.BACKGROUND: Mohs surgery is one of the most effective treatments for basal cell carcinomas. The expansion of its concepts enabled developing other equally effective methods to check surgical margins, and the Munich method is an example. OBJECTIVES: To evaluate the effectiveness of the Munich method of micrographic surgery in a ten-year cohort study. METHODS: Ninety-three patients with a total of 96 skin tumors were treated with the Munich method of micrographic surgery, taking part in a follow-up protocol, from May 1994 through July 2004. RESULTS: Of all tumors, 61.4% were recurrent, 42.3% were recurrent more than once, and 53% were of the sclerodermiform type. The mean larger diameter was 1.58cm, and the mean smaller diameter was 1.10cm. In 95% of the cases, total extirpation of the tumor was obtained in three stages. The most common site was nasal (46.3%), followed by periocular (18.9%) and frontal (11.5%). Two patients were lost in follow-up. Of the 96 operated tumors, only 11 had a follow-up time shorter than 2 years. Fifty-six patients were followed for at least 5 years, and 45 (47.3%) for over 6 years. A single relapse was observed, which took place in the sixth year of observation. CONCLUSION: The Munich method is an efficient method of micrographic surgery, as good as the Mohs method. This study provides further evidence that the concept of micrographic surgery must be broadened to surgical excision with microscopic margin control, rather than linking it exclusively to the term "Mohs micrographic surgery".

Luis Fernando Figueiredo Kopke; Patricia Salomé Gouvêa; Jose Caldeira Ferreira Bastos

2005-01-01

369

L’utilisation du TENS en physiothérapie : la situation particulière des soins palliatifs oncologiques  

Directory of Open Access Journals (Sweden)

Full Text Available Trans-cutaneous electrical nerve stimulation (TENS) is a treatment against pain that uses the application of an electric current. Some studies suggest that TENS would reduce the pain associated with certain types of cancer and this treatment is regularly used in therapy in contexts of interdisciplinary practice specializing in palliative oncology. However, the use of TENS in cancer cases is a matter of controversy, and its application is contraindicated by Canadian standards governing the practice of physiotherapy. This article aims to present, through a case study, some principles to guide decision making regarding the choice of this therapy in cases of cancer. Scientific evidence, standards of practice and ethical principles that should guide the choice of therapy are discussed. The use of TENS therapy in palliative care is a paradigmatic example of a common situation: the weighing by health care professionals of the benefits and potential costs, such as potential adverse effects of treatment. In the case of TENS, the benefits are associated with the reduction of pain, while a potential adverse effect would increase tumour proliferation. This difficult calculation has implications for the various stakeholders such as patients and health professionals.

Laliberté, Maude; Dyer, Joseph-Omer

2012-01-01

370

Adding with Tens and Ones  

Science.gov (United States)

Students are asked to solve an addition problem and a subtraction problem that requires them to consider a variety of strategies, such as compensation, composing and decomposing, and using tens and ones.

Sherdan, Danielle

2010-07-12

371

Eccrine Angiomatous Hamartoma: A Retrospective Study of 15 Cases  

Directory of Open Access Journals (Sweden)

Full Text Available Background: Eccrine angiomatous hamartoma (EAH) comprises a rare nevoid proliferation of normal eccrine glands and small blood vessels and occasionally otherelements in the middle and deep dermis with variable clinical manifestations.Case series have rarely been published except for case reports and literaturereviews. The aims of this article were to investigate the clinical and pathologic features of patients with EAH in Taiwan and to compare our resultswith the results of previous studies.Methods: A retrospective review of medical records and histopathological findings wasperformed on patients diagnosed with EAH in a medical center in Taiwanbetween 1994 and 2010.Results: Fifteen patients with pathologically diagnosed EAH were collected. Themean age at the time of diagnosis was 38.6 years (range, birth to 67 years).The male to female ratio was 3 to 2. In most cases, EAH arose as a singlelesion on a lower extremity. The symptoms and signs most commonly associated with EAH were pain (60%), hypertrichosis (13.3%), itching (13.3%)and hyperhidrosis (6.7%). Additional pathological findings included hemangioma (13.3%), verrucous hemangioma (6.7%), arteriovenous malformation(6.7%), and angiokeratoma (6.7%). None of the patients experienced spontaneous regression of the lesions before excision. Excisions were done in onepatient under general anesthesia, and ten patients with local anesthesia. Fourpatients were kept under observation. Tumor recurrences were noted in twoout of the eleven patients whose lesions were excised.Conclusion: Compared with cases in the literature, we found additional histopathologicalfindings and an increased tumor recurrence risk in our cohort. EAH remainsa benign and uncommon hamartomatous condition. Further multi-center, retrospective studies with larger case numbers are needed to better characterizethe disease presentation in Asian populations.

Yi-Ting Lin; Chien-Ming Chen; Chih-Hsun Yang; Yea-Huey Chuang

2012-01-01

372

BTS Case Study: The Galloway Family Home  

Energy Technology Data Exchange (ETDEWEB)

Case study of an energy-efficient Habitat for Humanity house that uses 30% less energy than conventional residential construction. The project was part of the Jimmy Carter Work Project in rural Appalachia in 1997.

Brandegee Group.

1999-03-08

373

BTS Case Study: The Galloway Family Home  

International Nuclear Information System (INIS)

Case study of an energy-efficient Habitat for Humanity house that uses 30% less energy than conventional residential construction. The project was part of the Jimmy Carter Work Project in rural Appalachia in 1997.

1999-01-01

374

Share Food Case Study Packet. Executive Summary.  

Science.gov (United States)

A Baldrige case study packet is composed of the tools used to train Baldrige Examiners and of the Examiners working documents in the evaluation process. As such, the packet demonstrates the Baldrige Award application and evaluation processes and provides ...

2007-01-01

375

Long-term follow-up of replacement compared with internal fixation for displaced femoral neck fractures: results at ten years in a randomised study of 450 patients.  

UK PubMed Central (United Kingdom)

In a series of 450 patients over 70 years of age with displaced fractures of the femoral neck sustained between 1995 and 1997 treatment was randomised either to internal fixation or replacement. Depending on age and level of activity the latter was either a total hip replacement or a hemiarthroplasty. Patients who were confused or bed-ridden were excluded, as were those with rheumatoid arthritis. At ten years there were 99 failures (45.6%) after internal fixation compared with 17 (8.8%) after replacement. The rate of mortality was high at 75% at ten years, and was the same in both groups at all times. Patient-reported pain and function were similar in both groups at five and ten years. Those with successfully healed fractures had more hip pain and reduction of mobility at four months compared with patients with an uncomplicated replacement, and they never attained a better outcome than the latter patients regarding pain or function. Primary replacement gave reliable long-term results in patients with a displaced fracture of the femoral neck.

Leonardsson O; Sernbo I; Carlsson A; Akesson K; Rogmark C

2010-03-01

376

Ground-source heat pump case studies and utility programs  

Energy Technology Data Exchange (ETDEWEB)

Ground-source heat pump systems are one of the promising new energy technologies that has shown rapid increase in usage over the past ten years in the United States. These systems offer substantial benefits to consumers and utilities in energy (kWh) and demand (kW) savings. The purpose of this study was to determine what existing monitored data was available mainly from electric utilities on heat pump performance, energy savings and demand reduction for residential, school and commercial building applications. In order to verify the performance, information was collected for 253 case studies from mainly utilities throughout the United States. The case studies were compiled into a database. The database was organized into general information, system information, ground system information, system performance, and additional information. Information was developed on the status of demand-side management of ground-source heat pump programs for about 60 electric utility and rural electric cooperatives on marketing, incentive programs, barriers to market penetration, number units installed in service area, and benefits.

Lienau, P.J.; Boyd, T.L.; Rogers, R.L.

1995-04-01

377

The comparison of grey-scale ultrasonic and clinical features of hepatoblastoma and hepatocellular carcinoma in children: a retrospective study for ten years  

Directory of Open Access Journals (Sweden)

Full Text Available Abstract Background Hepatoblastoma (HBL) and hepatocellular carcinoma (HCC) are respectively the first and the second most common pediatric malignant liver tumors. The purpose of this study was to evaluate the combined use of the ultrasound examination and the assessment of the patients' clinical features for differentiating HBL from HCC in children. Methods Thirty cases of the confirmed HBL and 12 cases of the confirmed HCC in children under the age of 15 years were enrolled into our study. They were divided into the HBL group and the HCC group according to the histological types of the tumors. The ultrasonic features and the clinical manifestations of the two groups were retrospectively analyzed, with an emphasis on the following parameters: onset age, gender (male/female) ratio, positive epatitis-B-surface-antigen (HBV), alpha-fetoprotein increase, and echo features including septa, calcification and liquefaction within the tumors. Results Compared with the children with HCC, the children with HBL had a significantly younger onset age (8.2 years vs. 3.9 years, P Conclusion Ultrasonic features combined with clinical manifestations are valuable for differentiating HBL from HCC in children.

Zhuang Hua; Peng Yu-lan; Chen Tian-wu; Jiang Yong; Luo Yan; Zhang Qiong; Yang Zhi-gang

2011-01-01

378

NWCC Transmission Case Study Conclusions Summary  

Energy Technology Data Exchange (ETDEWEB)

OAK-B135 The NWCC Transmission Case Studies Conclusions Summary In the spring of 1999, the Utility Wind Interest Group (UWIG), with the cooperation of the National Wind Coordinating Committee (NWCC), conducted a forum on transmission issues associated with the production of energy from wind. As a result of this forum, a number of issues were identified which, if successfully resolved, could help reduce barriers to the future expansion of wind power. The NWCC, being a multi-stakeholder group, was in an ideal position to conduct follow-up activities among a cross-section of the interested parties. The follow-up activities took the form of three case studies in the areas of interest identified by forum participants: (1) Transmission policy and pricing; (2) ''Virtual wheeling'' arrangements; and, (3) Transmission system improvements. The case studies provide an interesting snapshot in time dealing with a range of issues associated with scheduled or planned regulatory and restructuring proceedings related to energy transmission. The NWCC Transmission Subcommittee and the UWIG reviewed early drafts of the case studies in November 1999. The case studies were conducted through a questionnaire and interview process with interested parties. In writing each case study, NWCC staff attempted to identify all stakeholder groups with an interest in each topic and solicit their input. While all parties do not agree on every issue presented, a serious effort has been made to present all views in an unbiased fashion. At the end of each case study, relevant conclusions are drawn and recommendations for next steps are provided where appropriate.

Steve Wiese, Terry Allison

2000-09-01

379

Feigning not equal malingering: a case study.  

UK PubMed Central (United Kingdom)

Researchers and scholars assert that feigning should not be equated with malingering. Some practicing clinicians doing the everyday work of forensic assessment may view this as merely an academic distinction. This case study illustrates that a high level of certainty about feigning must not be considered indicative of malingering. The case also contrasts two models for assessing malingering and highlights the need for forensic examiners to present assessment-of-malingering data clearly and cautiously.

DeClue G

2002-01-01

380

Feigning not equal malingering: a case study.  

Science.gov (United States)

Researchers and scholars assert that feigning should not be equated with malingering. Some practicing clinicians doing the everyday work of forensic assessment may view this as merely an academic distinction. This case study illustrates that a high level of certainty about feigning must not be considered indicative of malingering. The case also contrasts two models for assessing malingering and highlights the need for forensic examiners to present assessment-of-malingering data clearly and cautiously. PMID:12465136

DeClue, Gregory

2002-01-01

 
 
 
 
381

Case Study Report about Gender Impact Assessment  

DEFF Research Database (Denmark)

The aim of this national case study report is to take a closer look at the use of Gender Impact Assessments in Denmark in order to describe the Danish implementation of this specific Gender Mainstreaming method. By way of analyzing two selected cases (two law proposals put forward by The Danish Ministry of Employment and the Danish Ministry of Transport, respectively) the aim is to assess the transformative potential of GIA as it is performed in Denmark.

Faber, Stine Thidemann; Agustin, Lise Rolandsen

2013-01-01

382

Nuclear forensic investigations: two case studies.  

UK PubMed Central (United Kingdom)

This paper describes the methodology and analytical methods used in nuclear forensic investigations. Two case studies are taken as examples to illustrate this. These examples represent typical cases that have been analysed at the Institute for Transuranium Elements (ITU) since last 10 years, i.e. the beginning of the illicit trafficking of nuclear materials. Results of the various analytical techniques are shown, which, together with other type of information, reveal the origin of the material.

Wallenius M; Mayer K; Ray I

2006-01-01