Energy Technology Data Exchange (ETDEWEB)

The advent of sophisticated automation equipment and computer hardware and software is changing the way manufacturing is carried out. To compete in the global marketplace, manufacturing companies must integrate these new technologies into their factories. In addition, they must integrate the planning, control, and data management methodologies needed to make effective use of these technologies. This paper provides an overview of recent approaches to achieving this enterprise integration. It then describes, using simulation as a particular example, a new tool`s perspective of enterprise integration.

Science.gov (United States)

In 2000, the Accreditation Council of Graduate Medical Education (ACGME) laid out a definition of competence that included six specific areas of focus: patient care (including clinical reasoning), medical knowledge, practice-based learning and improvement, interpersonal and communication skills, professionalism, and systems-based practice. The ACGME's intention was to mandate increasingly reliable and valid assessment measures to be used by all training programs over the next decade, with the goal of providing "more credible, accurate, reliable and useful educational outcome data." In this article, the authors will review definitions of competency according to the new ACGME standards and examine the assessment tools currently available, including global evaluations, 360-degree evaluations, checklists, standardized examinations and direct observations. The authors will provide an overview of critical considerations in ...

UK PubMed Central (United Kingdom)

Lists of reportable conditions and case definitions are important tools for epidemiologic surveillance. As part of an initiative to encourage occupational disease surveillance systems linked to intervention...Full Text Available

UK PubMed Central (United Kingdom)

RNA interference (RNAi) is an effective tool for studying gene function in oocytes, but no studies have targeted somatic cells of primary cultured cumulus cell-oocyte complexes (COCs). This...Full Text Available

Science.gov (United States)

PMID:17885319

CERN Document Server

The ALICE experimental area management team faces various challenges when it comes to sharing scarce resources, indispensable to any efficient installation in a category one worksite. Space, cranes, jigs, and personnel with key competences have to be carefully allocated to activities so as to avoid slowing down work progress. To this intent, a resource loaded planning has been developed that allows highlighting coactivities and prioritizing critical tasks. It uses the built-in capabilities of Microsoft Project. The use of this scheduling tool leads to a more efficient use of time and a safer work environment. The installation sequence resulting from this schedule is presented in this paper. The first part of the sequence focuses on the revision of the coils in the SX2 building. The dipole has then to be installed in the RB26 side of the UX25 cavern. This complex and resource intensive activity has to be performed in parallel with the services ...

International Nuclear Information System (INIS)

The talk will focus on spin-dependent competition between oblate and prolate shape minima in the potential energy landscape of "1"8"0Hf (the most neutron-rich stable isotope), mediated via the alignment of valence nucleons. Results of a prompt spectroscopic study, using deep inelastic reactions with Gammasphere and CHICO, bombarding a thin "2"3"2Th target with a "1"8"0Hf beam #approx#25% above the Coulomb barrier, will be presented. Nucleon alignments in both prolate and oblate minima will be discussed, as well as the favoring of oblate collective rotation at high spins, observed through a mixing with gamma vibrations built on the prolate shape.

UK PubMed Central (United Kingdom)

ObjectivesTo assess Croatian community pharmacists' patient care competencies using the General Level Framework (GLF).MethodsThe competencies of...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

A 1984 American Association of the Academy of Sciences study of more than 150 successful science in-service programs developed a list of their characteristics, which included: Strong academic component in mathematics, science, and communications, focused on enrichment rather than remediation; academic subjects taught by teachers who are highly competent in the subject matter and believe that students can learn the materials; heavy emphasis on the applications of science and mathematics and careers in these fields; integrative approach to teaching that incorporates all subject areas, hands-on opportunities, and computers; multiyear involvement with students; recruitment of participants from all relevant target populations; opportunities for in-school and out-of-school learning experiences; parental involvement and development of base of community support; specific attention to removing educational inequalities related to race and gender; ...

Science.gov (United States)

ACCEPTING THE CHALLENGE: EXAMINING INFANTRY AND MILITARY POLICE EMPLOYMENT OF COMPETENCIES ON THE TWENTY-FIRST ...

Energy Technology Data Exchange (ETDEWEB)

The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab) Laboratory Directed Research and Development Program FY 1996 report is compiled from annual reports submitted by principal investigators following the close of the fiscal year. This report describes the projects supported and summarizes their accomplishments. It constitutes a part of the Laboratory Directed Research and Development (LDRD) program planning and documentation process that includes an annual planning cycle, projection selection, implementation, and review. The Berkeley Lab LDRD program is a critical tool for directing the Laboratory`s forefront scientific research capabilities toward vital, excellent, and emerging scientific challenges. The program provides the resources for Berkeley Lab scientists to make rapid and significant contributions to critical national science and technology problems. The LDRD program also advances the Laboratory`s core competencies, ...

CERN Multimedia

Software Development Tools Service

Science.gov (United States)

In the last decade, directed evolution has become a routine approach for engineering proteins with novel or altered properties. Concurrently, a trend away from purely 'blind' randomization strategies and towards more 'semi-rational' approaches has also become apparent. In this review, we discuss ways in which structural information and predictive computational tools are playing an increasingly important role in guiding the design of randomized libraries: web servers such as ConSurf-HSSP and SCHEMA allow the prediction of sites to target for producing functional variants, while algorithms such as GLUE, PEDEL and DRIVeR are useful for estimating library completeness and diversity. In addition, we review recent methodological developments that facilitate the construction of unbiased libraries, which are inherently more diverse than biased libraries and therefore more likely to yield improved variants. PMID:16095966

Environmental Research Database

ObjectivesThe overall aim of the project is to understand whether natural Mn oxides can be used to remediate land contaminated with both metals and POPs. The major objectives are:~%~~%~1.Establishment of whether and how metals, POPs and SOM compete for reactive Mn oxide surface.~%~~%~2.Delineate the mechanisms of contaminant immobilisation and degradation.~%~~%~3.Identify the fate of the contaminants in Mn oxide treated soils.~%~~%~4.Measure positive and/or negative effects in the soil system of addition [continued...]DescriptionLand is a valuable but finite resource. The Environment Agency estimates that there are approximately 300,000 hectares of land in the UK affected to some extent by contamination left by industrial activity and worldwide, the extent of the problem is much greater as contaminated land is inextricably linked to poverty. In the UK, the increasing demand for new housing ...

Energy Technology Data Exchange (ETDEWEB)

This paper describes the challenges involved in the construction of a mid-rise housing development in Boston, Massachusetts, during which the development team elected to upgrade the initial design criteria from Minimum Building Code to Energy Star and Leadership in Energy and Environmental Design (LEED) certification. The various constraints imposed on the development were discussed, including constraints imposed by the involvement of substantial public funds as well as the constraints imposed by various funding sources that were approached to leverage energy efficiency and green building investment via competitive grant solicitations. Building owner and utility cost management priorities were outlined along with details of central mechanical system selection. Issues concerning isolation and compartmentalization were examined along with indoor pollution source control. A building load analysis was presented as well as details of daily heating and cooling statistics. Electric generation ...

International Nuclear Information System (INIS)

Gallium liquid-metal ion sources that have been introduced in the late 1970s have allowed the development of a new class of micro- and nanofabrication tools collectively denominated as focused ion beam (FIB) machines. To investigate the potential of a helium beam in such a FIB instrument the authors have tested a room-temperature electron beam ion trap coupled with a high resolution FIB machine. In this letter they present their first results in target imaging using a helium beam with a resolution that allows to account for a beam diameter in the submicrometer range.

Science.gov (United States)

Lanthanide-ion doped oxide nanoparticles were functionalized for use as fluorescent biological labels. These nanoparticles are synthesized directly in water which facilitates their functionalization, and are very photostable without emission intermittency. Nanoparticles functionalized with guanidinium groups act as artificial toxins and specifically target sodium channels. They are individually detectable in cardiac myocytes, revealing a heterogeneous distribution of sodium channels. Functionalized oxide nanoparticles appear as a novel tool particularly well adapted to long-term single-molecule tracking.

UK PubMed Central (United Kingdom)

The competence of pedicel explants of tobacco (Nicotiana tabacum L. cv Samsun) to regenerate flower buds in response to auxin was manipulated by preincubating excised tissues in the...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

A core competency is a distinguishing integration of capabilities which enables an organization to deliver mission results. Core competencies represent the collective learning of an organization and provide the capacity to perform present and future missions. Core competencies are distinguishing characteristics which offer comparative advantage and are difficult to reproduce. They exhibit customer focus, mission relevance, and vertical integration from research through applications. They are demonstrable by metrics such as level of investment, uniqueness of facilities and expertise, and national impact. The Oak Ridge National Laboratory (ORNL) has identified four core competencies which satisfy the above criteria. Each core competency represents an annual investment of at least $100M and is characterized by an integration of Laboratory technical foundations in physical, chemical, ...

Energy Technology Data Exchange (ETDEWEB)

Indicators are important tools for communicating and making accessible scientific and technical information to policymakers and the general public. They therefore play an important role in transforming information into action. Worldwide, many initiatives are underway to construct indicators for a variety of purposes, including those for reporting on sustainable development. This paper briefly describes the attempts made so far, but stresses that the users of the indicators should play a greater role in indicator construction. In developing countries, a substantial lack of data has meant that specific policy formulation may develop without adequate technical input. In developed countries also, data gaps may hinder policy formulation, implementation, and evaluation. However, the development of indicators as tools to assist in the management of hazardous wastes and toxic chemicals is still in the early stages of formulation. A more imaginative ...

Science.gov (United States)

Following the February 2011 earthquake in Christchurch, New Zealand (NZ), the authors participated in counselling local residents, and debriefing and supervising support teams. Indications were that risk for mental health disorders, including Post-Traumatic Stress Disorder (PTSD), may be elevated in residents, and that this risk may continue for some time. Patients may be de-prioritising their mental health issues when these become normalised throughout the city's population. The authors recommend that primary care patients are assessed using a brief, comprehensive tool (for example, the Case-finding and Help Assessment Tool) that targets many health and behavioural issues identified as increasing in the city following the earthquake. Anxiety and mood disorder symptoms may indicate assessment is appropriate to reduce harm arising from increased risk for PTSD. Concern also is raised for primary health care providers who may ...

Energy Technology Data Exchange (ETDEWEB)

The ALICE heavy-ion particle physics experiment is currently being built at CERN near Geneva. It will use a PC cluster of 900 dual-processor machines for the last stages of the data readout process and a network of 400 microcomputers for the configuration and control of the cluster nodes. One of the most important objectives to be achieved in such experiments is to guarantee the utilized devices are running correctly during the experiment life-time. A second aspect is the extremely high availability and reliability requirements of the applications being run, the so called high level trigger (HLT). The SysMES framework is a scalable, decentralized, fault tolerant, dynamic, rule based tool set for the monitoring of networks of target systems and applications. The management algorithms consist of the following steps: system and application monitoring, recognition of undesirable states, event (message) generation, local event handling on the ...

Science.gov (United States)

We report here results of an application of single-nucleon stripping reactions at high energies (65 MeV/u) in inverse kinematics to obtain spectroscopic factors. From measurements of the partial cross-sections for ground and excited states in residual nuclei formed in one-proton stripping reactions, single particle orbits and occupancies of light nuclei have been studied in the s-d shell. Single proton stripping cross-sections of {sup 25}Al and {sup 26,27,28}P on a Be target have been measured using the S800 spectrograph and the NaI(Tl) array at the NSCL. These results indicate that this technique may provide a general tool for the intermediate energy range analogous to transfer (pick-up) reactions at low-energy.

British Library Electronic Table of Contents (United Kingdom)

Coumarin (1,2-benzopyrone) is occurring in food, and is also used in cosmetics. In order to perform a risk assessment for both oral and dermal exposure, we applied a physiologically based approach to model kinetics in humans by simulating both routes of exposure. The concentration-time profile in liver revealed a higher peak concentration (Cmax-hep) for the oral when compared to the dermal route. The area under the concentration-time curve in the liver (AUChep) was found the same for both routes if the same extent of absorption is assumed. Dose response information from published rat studies were used to identify the metric relevant for liver toxicity. Liver exposure levels resulting from doses and durations as outlined in the studies were simulated in a rat model. We obtained 31 data pair...

Science.gov (United States)

The purpose of this project is to demonstrate targeted infill and extension drilling opportunities, better determinations of oil-in-place, methods for improved completion efficiency and the suitability of waterflooding in certain shallow-shelf carbonate reservoirs in the Williston Basin, Montana, North Dakota and South Dakota. Improved reservoir characterization utilizing 3-dimensional and multi-component seismic area is being investigated for identification of structural and stratigraphic reservoir compartments. These seismic characterization tools are integrated with geological and engineering studies. Improved completion efficiency is being tested with extended-reach jetting lance and other ultra-short radius lateral technologies. Improved completion efficiency, additional wells at closer spacing and better estimates of oil-in-place will result in additional oil production by primary and enhanced recovery processes.

Science.gov (United States)

The purpose of this project is to demonstrate targeted infill and extension drilling opportunities, better determinations of oil-in-place, methods for improved completion efficiency and the suitability of waterflooding in certain shallow-shelf carbonate reservoirs in the Williston Basin, Montana, North Dakota and South Dakota. Improved reservoir characterization utilizing 3-dimensional (3D) and multi-component seismic are being investigated for identification of structural and stratigraphic reservoir compartments. These seismic characterization tools are integrated with geological and engineering studies. Improved completion efficiency is being tested with short-lateral and horizontal drilling technologies. Improved completion efficiency, additional wells at closer spacing and better estimates of oil-in-place will result in additional oil production by primary and enhanced recovery processes.

Energy Technology Data Exchange (ETDEWEB)

The purpose of this project is to demonstrate targeted infill and extension drilling opportunities, better determinations of oil-in- place, methods for improved completion efficiency and the suitability of waterflooding in certain shallow-shelf carbonate reservoirs in the Williston Basin, Montana, North Dakota and South Dakota. Improved reservoir characterization utilizing 3-dimensional (3D) and multi- component seismic are being investigated for identification of structural and stratigraphic reservoir compartments. These seismic characterization tools are integrated with geological and engineering studies. Improved completion efficiency is being tested with short- lateral and horizontal drilling technologies. Improved completion efficiency, additional wells at closer spacing and better estimates of oil-in-place will result in additional oil production by primary and enhanced recovery processes.

Energy Technology Data Exchange (ETDEWEB)

The purpose of this project is to demonstrate targeted infill and extension drilling opportunities, better determinations of oil-in- place, methods for improved completion efficiency and the suitability of waterflooding in certain shallow-shelf carbonate reservoirs in the Williston Basin, Montana, North Dakota and South Dakota. Improved reservoir characterization utilizing 3-dimensional (3-D) and multi-component seismic are being investigated for identification of structural and stratigraphic reservoir compartments. These seismic characterization tools are integrated with geological and engineering studies. Improved completion efficiency is being tested with short-lateral and horizontal drilling technologies. Improved completion efficiency, additional wells at closer spacing and better estimate of oil-in-place will result in additional oil production by primary and enhanced recovery processes.

Energy Technology Data Exchange (ETDEWEB)

The purpose of this project is to demonstrate targeted infill and extension drilling opportunities, better determinations of oil-in-place, methods for improved completion efficiency and the suitability of waterflooding in certain shallow-shelf carbonate reservoirs in the Williston Basin, Montana, North Dakota and South Dakota. Improved reservoir characterization utilizing three-dimensional is being investigated for identification of structural and stratigraphic reservoir compartments. These seismic characterization tools are integrated with geological and engineering studies. Improved completion efficiency is being tested with short-lateral and horizontal drilling technologies. Improved completion efficiency, additional wells at closer spacing and better estimates of oil-in-place will result in additional oil production by primary and enhanced recovery processes.

Energy Technology Data Exchange (ETDEWEB)

The publication presents an outline of the subject of energy management and attempts to test the hypotheses that targeted knowledge management may result in new developments and potentials, and if these are at all desirable. On this basis, a knowledge management system will be developed that may effectively promote developments and potentials in the field of energy management. The tools and fundamentals of energy management are looked into, and the given situation and desired goals are identified by means of an enquiry. This is a scientific study that aims at providing empirical information on the situation and views on the subject of energy management. The analysis, which is supported by an enquiry sheet, is to provide a basis for testing the assumed hypothesis. Further, the potential acceptance and utilization potential of decisive knowledge management in the facility and real estate management sector are to be tested. The energy knowledge ...

British Library Electronic Table of Contents (United Kingdom)

The integrity of the cables located in the target room is very important in the Fire PSA, because the CDF and CCDP are changed according to the results of a cable integrity that depends on the surrounding gas temperature. The conservative assumptions used in the Fire PSA typically specify that all of the equipment and cables of a room would fail when a fire happens in the room. But the realistic assessment of a fire risk by using a fire simulation tool has become necessary in the Fire PSA as described in the ANS Fire PRA Standard. This paper evaluates the cable integrity of eight pump rooms in the nuclear power plant by using the CFAST zone fire model. The upper layer gas temperature of each room is estimated, and an analysis based on the results of model simulations is used to judge the c...

Energy Technology Data Exchange (ETDEWEB)

Utilities looking to thrive in increasingly competitive markets are reexamining their approach to pricing. To compete effectively, utilities will need to both control costs and offer customers pricing options that are competitive and reflect the diversity in their customer base. These price structures must reflect two key factors -- marginal costs, which will increasingly reflect market prices, and consumers` responsiveness to those price structures. To accomplish this requires the capability to forecast customers` response to price structures that often provide complex signals to customers about how changes in their energy consumption and maximum power demand affect their bill, and to calculate corresponding changes in utility profits and customer net benefits. Much discussion of competitive pricing focuses on innovative new rate structures. However, significant opportunities are present to improve matters by simply redesigning current traditional rate forms. This ...

Energy Technology Data Exchange (ETDEWEB)

Biosorption using activated sludge biomass (ASB) as a potentially sustainable technology for the treatment of wastewater containing different metal ions (Cd(II), Pb(II) and Zn(II)) was investigated. ASB metal uptake clearly competed with protons consumed by microbial biomass compared with control tests with non-activated sludge biomass. Biosorption tests confirmed maximum exchange between metal ions and protons at pH 2.0-4.5. It was revealed by the study that the amount of metal ions released from the biomass increased with biomass sludge concentration. The result showed that maximum absorption of metal ions was observed for Cd(II) at pH 3.5, Pb(II) at pH 4.0, and pH 4.5 for Zn(II) ions. The maximum absorption capacities of ASB for Cd(II), Pb(II) and Zn(II) were determined to be 59.3, 68.5 and 86.5%, respectively. The biosorption of heavy metals was directly proportional to ASB stabilization corresponding to a reduction in heavy metals in the order of ...

DEFF Research Database (Denmark)

Udgivelsesdato: 2002-Mar

Energy Technology Data Exchange (ETDEWEB)

This is the Fiscal Year 1995 Annual Report for the Advanced Manufacturing Science and Technology (AMST) sector of Los Alamos Tactical Goal 6, Industrial Partnering. During this past fiscal year, the AMST project leader formed a committee whose members represented the divisions and program offices with a manufacturing interest to examine the Laboratory`s expertise and needs in manufacturing. From a list of about two hundred interest areas, the committee selected nineteen of the most pressing needs for weapon manufacturing. Based upon Los Alamos mission requirements and the needs of the weapon manufacturing (Advanced Design and Production Technologies (ADaPT)) program plan and the other tactical goals, the committee selected four of the nineteen areas for strategic planning and possible industrial partnering. The areas selected were Casting Technology, Constitutive Modeling, Non-Destructive Testing and Evaluation, and Polymer Aging and Lifetime Prediction. For each area, the AMST ...

Science.gov (United States)

Parenting programmes are effective interventions for preventing and treating conduct problems in young children. Up to 20% of children in disadvantaged areas have conduct disorder. Recent government initiatives such as targeting early years services to designated disadvantaged Flying Start areas in Wales have resulted in increased nursery-care provision for pre-schoolers, yet little has been done to equip nursery staff with effective child behaviour management strategies. The purpose of this non-randomised trial platform study was to establish the feasibility of delivery and the effectiveness of the new Incredible Years Toddler Parent Programme in supporting nursery staff in managing difficult behaviour in the nursery. The Parent Programme is a 12-session (a two-hour session/week) course for carers/parents of children aged one to three years old, which encourages carers to: establish positive relationships with children through play and child-centred activities; ...

Energy Technology Data Exchange (ETDEWEB)

Over the past 40 years, cavern storage of LPG's, petrochemicals, such as ethylene and propylene, and other petroleum products has increased dramatically. In 1991, the Gas Processors Association (GPA) lists the total U.S. underground storage capacity for LPG's and related products of approximately 519 million barrels (82.5 million cubic meters) in 1,122 separate caverns. Of this total, 70 are hard rock caverns and the remaining 1,052 are caverns in salt deposits. However, along the eastern seaboard of the U.S. and the Pacific northwest, salt deposits are not available and therefore, storage in hard rocks is required. Limited demand and high cost has prevented the construction of hard rock caverns in this country for a number of years. The storage of natural gas in mined caverns may prove technically feasible if the geology of the targeted market area is suitable; and economically feasible if the cost and convenience of service is competitive with ...

UK PubMed Central (United Kingdom)

BackgroundChanges in levels of estradiol and progesterone that occur with the transition to reproductive senescence may influence nociception or affect.Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Several recent improved methods for the EGFM are introduced in order to avoid artificial holes seen in the synthetic acceleration spectrum. Furthermore evaluation of input ground motions at Wolsung NPP are performed by varying the source parameters that may control the high-frequency wave radiation and the deviation of the synthetic motions are revealed. The PSHA case studies for four NPP sites (Wolsung, Kori, Uljin, Younggwang) are performed. In the analysis, site-specific attenuation equations developed for Korean NPP sites are employed, and the seismic hazards for the target sites are evaluated in the case where the four kind of seismic source models are considered. Moreover, the PSHA for Wolsung and Younggwang are conducted by using the site-specific attenuation equation with the index of response spectra and the uniform hazard spectra are evaluated for the two sites. The supporting tool for seismic response analysis and the evaluation ...

Energy Technology Data Exchange (ETDEWEB)

This guide is one of the actions following from the recommendations of the Thermie B project that aimed to support the development of a new European Integrated Clean Coal (CCT) Program concept (STR - 1121 - 96), November 1998. The concept aimed to enhance the market deployment of EU CCTs. This guide is prepared for EU industry to help them finding support for their CCT exports to the target markets. The guide will include easy accessible information on the most relevant EC-programs and is intended as a practical tool for EU CCT industry, to assist them in identifying and selecting the export support and programs best able to support their specific export assistance. The guide is a manual (signpost) through the 'jungle of assistance' and therefore does not include extensive information on application procedures, since this kind of information can be easily obtained, once the relevant program is identified. Also information will ...

Science.gov (United States)

A study examined the concept of interpersonal communication competence in order to construct a more refined instrument than those currently used to measure competence. Using 70 items drawn from several existing measures of competence, 660 volunteer subjects from undergraduate communication courses at a large midwestern university provided their conception of adept and inept communicators, defined respectively as the best and worst communicators they know. Direct and multiple step-wise discriminant analyses were performed to determine the extent to which these items best discriminated between subjects' conceptions of adept and inept communicators, and to determine which of the 70 items best discriminated between these conceptions. Canonical discriminant functions revealed that the subjects clearly distinguished between adept and inept communicators. Classification results revealed that nearly 97% of the cases were ...

Wastenet

Labeling of organic res- taurants, cantinas, etc.

Energy Technology Data Exchange (ETDEWEB)

No abstract prepared.

Science.gov (United States)

We report a search for small RNAs (sRNAs) in the low-GC, gram-positive human pathogen Streptococcus pneumoniae. Based on bioinformatic analyses by Livny et al. (J. Livny, A. Brencic, S. Lory, and M. K. Waldor, Nucleic Acids Res. 34:3484-3493, 2006), we tested 40 candidates by Northern blotting and confirmed the expression of nine new and one previously reported (CcnA) sRNAs in strain D39. CcnA is one of five redundant sRNAs reported by Halfmann et al. (A. Halfmann, M. Kovacs, R. Hakenbeck, and R. Bruckner, Mol. Microbiol. 66:110-126, 2007) that are positively controlled by the CiaR response regulator. We characterized 3 of these 14 sRNAs: Spd-sr17 (144 nucleotides [nt]; decreased in stationary phase), Spd-sr37 (80 nt; strongly expressed in all growth phases), and CcnA (93 nt; induced by competence stimulatory peptide). Spd-sr17 and CcnA likely fold into structures containing single-stranded regions between hairpin structures, whereas Spd-sr37 forms a base-paired ...

Energy Technology Data Exchange (ETDEWEB)

In the framework of nuclear waste transmutation studies, the Mini-INCA project has been initiated at CEA/DSM with objectives to determine optimal conditions for transmutation and incineration of minor actinides (MA) in high intensity neutron fluxes. Our experimental tools based on alpha- and gamma-spectroscopy of the samples and the development of micro fission chambers could gather either microscopic information on nuclear reactions (total or partial cross sections for neutron capture and/or fission reactions) or macroscopic information on transmutation and incineration potentials. Neutron capture cross sections of selected actinides ({sup 241}Am, {sup 242}Am, {sup 242}Pu, {sup 237}Np) have already been measured at ILL, showing some discrepancies when compared to evaluated data libraries but in overall good agreement with recent data. The studies and possibilities offer by the MEGAPIE project to assess neutronic performances of a 1 MW spallation ...

Science.gov (United States)

The Department of Defense (DoD) has long depended on military support functions enabled by space reconnaissance, surveillance, and target acquisition (RSTA) assets. Future generation satellite capabilities will further push technologies in space - if the right technologies are deployed in the right numbers and with the right payloads. Modeling and simulation play major parts in developing and deploying such assets: 1) system and operational requirements determination, and 2) assessment of military utility of such assets. Each area is critical in a system"s life cycle. Requirements determination cuts across the issues of doctrine, organizations, training, materiel, leader development, personnel, and facilities (DOTMLPF). Military utility assessments are necessary to explore and quantify the military worth/benefit of space RSTA assets to operational commanders. Each of these areas requires relevant modeling/simulation tools which span the ...

Energy Technology Data Exchange (ETDEWEB)

The uncoupling protein (UCP) is a proton/anion transporter found in the inner mitochondrial membrane of brown adipocyte. Although UCP has nor been detected in mitochondria from any other tissue, it shares structural and catalytic properties with several other mitochondrial carrier proteins. Although UCP was discovered only recently it is one of the most extensively studied mitochondrial carrier proteins.More recently, the mouse, rat, and human genes encoding for UCP have been isolated and sequenced. The availability of these various tools has led to several significant observations. UCP gene expression is strongly controlled at the level of transcription by signals that are activated after the stimulation of brown adipocytes by norepinephrine. The comparison of UCP gene with the genes encoding the adenine nucleotide translocator revealed the existence of structural and evolutionary homologies. Moreover, in humans the UCP gene and one form of adenine nucleotide ...

Science.gov (United States)

Abnormal intracellular deposition of aggregated ?-synuclein is the characteristic feature of a number of neurological disorders, including Parkinson's disease (PD). Although ?-synuclein is typically known as a cytosolic protein, a small amount is secreted by exocytosis in both monomeric and aggregated forms. The extracellular forms of ?-synuclein in human body fluids, such as cerebrospinal fluid (CSF) and blood plasma, might be a diagnostic target for PD and related diseases. Here, we characterized a new set of monoclonal antibodies against ?-synuclein, and using different combinations of antibodies, we established ELISA systems to specifically detect human ?-synuclein, mouse and human ?-synuclein together, and multimeric forms of ?-synuclein in biological samples. By employing the Tyramide signal amplification method, the sensitivity of the assay was significantly improved to detect a concentration as low as ?12.5 pg/ml. These assays might be useful ...

International Nuclear Information System (INIS)

As part of efforts to develop improved methods for NMR protein sample preparation and structure determination, the Northeast Structural Genomics Consortium (NESG) has implemented an NMR screening pipeline for protein target selection, construct optimization, and buffer optimization, incorporating efficient microscale NMR screening of proteins using a micro-cryoprobe. The process is feasible because the newest generation probe requires only small amounts of protein, typically 30-200 ?g in 8-35 ?l volume. Extensive automation has been made possible by the combination of database tools, mechanization of key process steps, and the use of a micro-cryoprobe that gives excellent data while requiring little optimization and manual setup. In this perspective, we describe the overall process used by the NESG for screening NMR samples as part of a sample optimization process, assessing optimal construct design and solution conditions, as well as for ...

DEFF Research Database (Denmark)

One important market related capability for firms which seek to develop radical innovations is the competence to involve the 'right' users at the 'right' time in the 'right' form. While former studies have identified a rather passive role of users in the radical innovation process, this paper focuses on the involvement of such users that are in the position to play an active role as inventors and (co)-developers. A multiple case study analysis was conducted in the field of medical technology. Five radical innovation projects within four firms were selected including medical robots and computer-assisted navigation systems. The case study analysis reveals that firms who closely interact with specific users benefit significantly for their radical innovation work. These users have a high motivation toward new solutions, are open to new technologies, possess diverse competencies, and are embedded into a very supportive environment.

Energy Technology Data Exchange (ETDEWEB)

Threat characterization is a key component in evaluating the threat faced by control systems. Without a thorough understanding of the threat faced by critical infrastructure networks, adequate resources cannot be allocated or directed effectively to the defense of these systems. Traditional methods of threat analysis focus on identifying the capabilities and motivations of a specific attacker, assessing the value the adversary would place on targeted systems, and deploying defenses according to the threat posed by the potential adversary. Too many effective exploits and tools exist and are easily accessible to anyone with access to an Internet connection, minimal technical skills, and a significantly reduced motivational threshold to be able to narrow the field of potential adversaries effectively. Understanding how hackers evaluate new IT security research and incorporate significant new ideas into their own tools provides ...

J-STORE (Japan)

Full Text Available

UK PubMed Central (United Kingdom)

All microRNA (miRNA) target—finder algorithms return lists of candidate target genes. How valid is that output in a biological setting? Transcriptome analysis has proven to be a useful approach...Full Text Available

International Nuclear Information System (INIS)

This publication presents seven national case studies from a coordinated research project on Indicators for Sustainable Energy Development conducted during the 2002-2005 time period. The project was led by the International Atomic Energy Agency (IAEA) in cooperation with the United Nations Department of Economic and Social Affairs (UNDESA). The case studies were developed by research organizations from Brazil, Cuba, Lithuania, Mexico, Russia, Slovakia and Thailand. This publication is being issued just prior to the 15th session of the United Nations Commission on Sustainable Development for which energy for sustainable development is a major theme. The 15th session of the Commission will focus on policy decisions on practical measures and options to expedite implementation in selected clusters of energy issues. The application the energy indicator, especially their quantification, enables systematic monitoring of progress made towards the implementation of energy-related ...

International Nuclear Information System (INIS)

One of the limiting contributors to the heat load constraint for a long term spent fuel repository is the decay of americium-241. A possible option to reduce the heat load produced by Am-241 is to eliminate it via transmutation in a light water reactor thermal neutron environment, in particular, by taking advantage of the large thermal fission cross section of Am-242 and Am-242m. In this study we employ lattice loading optimization techniques to define the loadings and arrangements of fuel pins with blended americium and uranium oxide in boiling water reactor bundles, specifically, by defining the incineration of pre-loaded americium as an objective function to maximize americium transmutation. Subsequently, the viability of these optimized lattices is tested by assembling them into bundles with Am-spiked fuel pins and by loading these bundles into realistic three-dimensional BWR core-wide simulations that model multiple reload cycles and observe standard operational constraints. These ...

Energy Technology Data Exchange (ETDEWEB)

Extensive research into the treatment and control of Volatile Organic Compounds (VOCs) from semiconductor industry manufacturing processes has identified the need for alternatives to existing combustion devices. Specifically, semiconductor manufacturing design is moving toward exploiting effective, small-scale, abatement control technologies for specific point-of-use (POU) waste streams associated with a particular component or manufacturing tool. The Silent Discharge Plasma (SDP) developed at Los Alamos National Laboratory is a nonthermal plasma technology created by a dielectric-ballasted electrical discharge. Influent gas-phase pollutants are destroyed in the reactor by the free radicals or electrons generated by the plasma. This paper examines the potential for SDP to be used in niche circumstances for POU control of VOC exhaust streams specific to the semiconductor industry. A sensitivity analysis is presented, showing how SDP cost of ownership is affected by ...

UK PubMed Central (United Kingdom)

Sperm competition occurs when 2 or more males copulate with a particular female during the same reproductive cycle, and their sperm compete to fertilize the female's available eggs. One strategy that...Full Text Available

UK PubMed Central (United Kingdom)

ObjectiveTo implement a role-reversal exercise to increase first-year pharmacy students' awareness of communication barriers in the health care setting, especially for deaf and hard-of-hearing...Full Text Available

UK PubMed Central (United Kingdom)

Multiple stimuli present in the visual field at the same time compete for neural representation by mutually suppressing their evoked activity throughout visual cortex, providing a neural correlate...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

The alternative to the use of deeper wells through temperature amplification of the geothermal resource by electric heat pumps is explored. Systems in Ephrata, Washington and Chamberlain, South Dakota are explored. (MHR)

UK PubMed Central (United Kingdom)

Oocyte-cumulus cell bidirectional communication is essential for normal development of the oocyte and cumulus cells (CCs) within the follicle. We showed recently that addition of recombinant growth...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Car-producers compete in launching hybrids and electric cars, but this does not mean the end for the good old combustion engine.The challenge is the introduction of more complexed costs and weight in the new technology. (AG)

Science.gov (United States)

...competent person shall inspect haulage equipment before each shift. (ii...used. (2) Powered mobile haulage equipment shall have suitable means of... (3)(i) Power mobile haulage equipment, including trains, shall...

Energy Technology Data Exchange (ETDEWEB)

Design tools that are currently available for use with microcomputers to assist in designing energy-efficient daylighted buildings are presented. The information presented was gathered as a part of a telephone survey to design tool developer conducted over a six month period. The matrix is but one of five categories of tools. The other four were nomographs, protractors/tables, minis, and main frame computer programs. Information is provided to encourage interested design professionals, educators and students to communicate directly with design tool representatives.

International Nuclear Information System (INIS)

The accuracy of dose computation within the lungs depends strongly on the performance of the calculation algorithm in regions of electronic disequilibrium that arise near tissue inhomogeneities with large density variations. There is a lack of data evaluating the performance of highly developed analytical dose calculation algorithms compared to Monte Carlo computations in a clinical setting. We compared full Monte Carlo calculations (performed by our Monte Carlo dose engine MCDE) with two different commercial convolution/superposition (CS) implementations (Pinnacle-CS and Helax-TMS's collapsed cone model Helax-CC) and one pencil beam algorithm (Helax-TMS's pencil beam model Helax-PB) for 10 intensity modulated radiation therapy (IMRT) lung cancer patients. Treatment plans were created for two photon beam qualities (6 and 18 MV). For each dose calculation algorithm, patient, and beam quality, the following set of clinically relevant dose-volume values was reported: (i) minimal, median, ...

Science.gov (United States)

Page 1. AD-769 272 A NEW TOOL FOR ACCURATELY MEASURING THE INSIDE DIAMETER OF A GUN BARREL, LONG TUBE, OR SIMILAR ...

UK PubMed Central (United Kingdom)

Human antibodies targeting prostate cancer cell surface epitopes may be useful for imaging and therapy. The objective of this study was to evaluate the tumor targeting of an internalizing human...Full Text Available

UK PubMed Central (United Kingdom)

Computational prediction of microRNA targets remains a challenging problem. The existing rule-based, data-driven and expression profiling approaches to target prediction are mostly approached from the...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

Cost is a key issue in the spreading of any technology. In this work, the cost of hydrogen is analyzed and determined, for hydrogen obtained by electrolysis. Different contributing partial costs are taken into account to calculate the hydrogen final cost, such as energy and electrolyzers taxes. Energy cost data is taken from official URLs, while electrolyzer costs are obtained from commercial companies. The analysis is accomplished under different hypothesis, and for different countries: Germany, France, Austria, Switzerland, Spain and the Canadian region of Ontario. Finally, the obtained costs are compared to those of the most used fossil fuels, both in the automotive industry (gasoline and diesel) and in the residential sector (butane, coal, town gas and wood), and the possibilities of hydrogen competing against fuels are discussed. According to this work, in the automotive industry, even neglecting subsidies, hydrogen can compete with fossil ...

Science.gov (United States)

... efforts in developing and testing prototype materials or tools and Full Development Projects to ...

Science.gov (United States)

Near-infrared spectroscopy is a convenient tool for measuring nanotube / carbonaceous impurities

KoreaScience (Korea)

Full Text Available

UK PubMed Central (United Kingdom)

In an effort to develop octahedral metal complexes as chemotherapeutic and diagnostic agents targeted to DNA, it is critical to optimize the properties of their cellular uptake. Appending d-octaarginine...Full Text Available

Science.gov (United States)

... L. Sutton. 2000. Is the aquatic weed hygrophila, Hygrophila polysperma (Polemoniales: Acanthaceae), a suitable target for classical biological ... ...

Science.gov (United States)

By W. Wayne Scott. Langley Research Center. SUMMARY. Thin- and thick-target bremsstrahlung spectra are presented for electron energies up to 7.0 MeV. ...

British Library Electronic Table of Contents (United Kingdom)

Background:- Discrepancies exist in optometric education, practice and regulation across the Asia-Pacific region and the competence of optometric practitioners in adopting new lens technologies may vary widely. Over the past 10-years, a continuing professional development program, Varilux Academy Asia-Pacific (VAAP), was implemented and conducted in countries across the Asia-Pacific region to improve practitioners' understanding of optometric fitting principles, with special emphasis on progressive addition lenses (PAL). The aim was to demonstrate the effectiveness of VAAP and to compare the competence of practitioners across the Asia-Pacific region in new lens fitting technologies. Methods:- From 2002 to 2008, all VAAP participants from 12 countries across Asia-Pacific were invited to com...

Energy Technology Data Exchange (ETDEWEB)

Consultant and advanced practice are relatively new concepts in radiography. There is evidence to show that as the career progression framework is being adopted the numbers of consultant and advanced practitioners in radiography are growing with the latter growing at a faster rate. The article considers the concept of advanced and consultant practice and the education requirements to support development. Preparation for an advanced practice role begins at the practitioner stage. Masters' level programmes are available to support the development of advanced practice. Education needs to be flexible as new advanced practice roles emerge. It is necessary to take practitioners beyond a defined modality to include leadership and people skills. These are essential for those aspiring to become consultants. Consultants require a high level of clinical knowledge for expert practice but also strategic vision and interpersonal intelligence to facilitate leadership and practice innovation. ...

Energy Technology Data Exchange (ETDEWEB)

The purpose of this paper is to inform commercial building designers about an energy analysis tool which can aid them in making appropriate decisions about daylighting. The energy nomographs are an energy design tool which calculate the annual energy consumption of commercial buildings, including lighting, heating, cooling, domestic hot water, fans, pumps, and miscellaneous items. This paper specifically discusses the daylighting aspects of the tool. The calculation procedure is presented with an example to explain how this design tool can be used to make good energy decisions early in the design process.

International Nuclear Information System (INIS)

Development in Instrumentation and Control (I and C) technology provides more convenience and better performance, thus, adopted in many fields. To adopt newly developed technology, nuclear industry requires rigorous V and V procedure and tests to assure reliable operation. Adoption of digital system requires verification and testing of the OS for licensing. Commercial real-time operating system (RTOS) is targeted to apply to various, unpredictable needs, which makes it difficult to verify. For this reason, simple, application-oriented realtime OS is developed for the nuclear application. In this work, we show how to verify the developed RTOS at each development lifecycle. Commercial formal tool is used in specification and verification of the system. Based on the developed model, software in C language is automatically generated. Tests are performed for two purposes; one is to identify consistency between the verified model and the generated ...

Energy Technology Data Exchange (ETDEWEB)

This topical report is a compilation of characterizations by different disciplines of the Red River Formation in the southwest portion of the Williston Basin and the oil reservoirs which it contains in an area which straddles the state line between North Dakota and South Dakota. Goals of the report are to increase understanding of the reservoir rocks, oil-in-place, heterogeneity, and methods for improved recovery. The report is divided by discipline into five major sections: (1) geology, (2) petrography-petrophysical, (3) engineering, (4) case studies and (5) geophysical. Interwoven in these sections are results from demonstration wells which were drilled or selected for special testing to evaluate important concepts for field development and enhanced recovery. The Red River study area has been successfully explored with two-dimensional (2D) seismic. Improved reservoir characterization utilizing 3-dimensional (3D) and has been investigated for identification of structural and ...

Science.gov (United States)

This paper builds upon previous work [Sprigg and Ehlen, 2004] by introducing a bond market into a model of production and employment. The previous paper described an economy in which households choose whether to enter the labor and product markets based on wages and prices. Firms experiment with prices and employment levels to maximize their profits. We developed agent-based simulations using Aspen, a powerful economic modeling tool developed at Sandia, to demonstrate that multiple-firm economies converge toward the competitive equilibria typified by lower prices and higher output and employment, but also suffer from market noise stemming from consumer churn. In this paper we introduce a bond market as a mechanism for household savings. We simulate an economy of continuous overlapping generations in which each household grows older in the course of the simulation and continually revises its target level of savings according to a life-cycle ...

Energy Technology Data Exchange (ETDEWEB)

This report describes the results of a program conducted at the Pacific Northwest Laboratory (PNL) and Westinghouse Hanford Company (WHC) to identify alternative methods to measure the surface level in the waste tanks. This program examined commercially available devices for measuring the distance to a target. This is a continuation of a program started in FY93. In the first test sequence, tests were performed.on five devices to determine their applicability to measure the surface level in the waste tanks. The devices were the Enraf-Nonius{trademark} Model 872 Radar Gauge, the Enraf-Nonius{trademark} Model 854 Advanced Technology Gauge (ATG), the Stanley Tool Laser Measuring Device, the Robertshaw Inven-Tel{reg_sign} Precision Level Gauge, and the Micro Switch Model 942 Acoustic Sensor. In addition, discussions were held with several manufacturer representatives regarding other potential devices. The results of these tests were documented in a ...

Energy Technology Data Exchange (ETDEWEB)

An uncertainty decrease is an very important issue for enhancing risk-informed (RI) activities worldwide. Especially, a relatively large uncertainty in a level-2 (L2) PSA risk compared with level-1 internal PSA risk has been a bottleneck problem in the RI application to the extent of a severe accident management. According to the ASME PRA standard in which sources of an uncertainty to capture a category-II RI (= Option 2) capability are listed, an uncertainty analysis which identifies the key sources of an uncertainty and includes sensitivity studies for dominant contributors to LERF (Large Early Release Frequency) needs to be provided. To solve these problems, USNRC have developed the 'SPAR-LERF' model related to the L2 RI application and 'L2 uncertainty assessment and improvement' work is being taken as a main PSA2 topic of the SARNET (Severe Accident Research Network of Excellence) program in Europe by OECD/NEA. Domestically, a mid/long-term R and ...

Energy Technology Data Exchange (ETDEWEB)

We proposed a solid and a mercury target concepts through the preliminary conceptual design. To feasible these concepts, analysis and experimental works are being carried out. This paper introduces an outline of present status of target R and D such as heat transfer augmentation experiments for the solid target, mercury flow tests with a loop of maximum flow rate of 15L/min, flow pattern measurements for a cold source moderator etc. as well as preliminary conceptual design works. (author)

Energy Technology Data Exchange (ETDEWEB)

Short communication.

KoreaScience (Korea)

Full Text Available

CERN Document Server

In the CERN approach to the design of a neutrino factory, the repetition frequency of the proton beam is high enough to consider stationary solid targets as a viable solution for multi-MW beams. The target consists of high density tantalum spheres of 2 mm diameter which can efficiently be cooled by passing a high mass flow He-gas stream through the voids between the Ta-granules. Very small thermal shocks and stresses will arise in this fine grained structure due to the relatively long burst of 3.3 ms from the SPL-proton linac. In a quadruple target system where each target receives only one quarter of the total beam power of 4 MW, conservative temperature levels and adequate lifetimes of the target are estimated in its very high radiation environment. A conceptual design of the integration of the target into the magnetic horn-pion-collector is presented.

Wastenet

... The larvae's only hope for survival is if the antibiotic tetracycline is present -because it mops up the enzyme. The developers hope male GM mosquitoes will compete with normal males for females so that repeated releases cut numbers of A. aegypti in dengue-prone areas. The mosquitoes will be released in the inland districts of Bentong in the state of Pahang, and Alor Gajah and Melaka in the state of Malacca, according to the National Biosafety Board. Each location will have two release phases: the first at a site ...

Energy Technology Data Exchange (ETDEWEB)

Lysozyme activities of serum and urine in normal subjects, patients with various leukemias, and a-bomb survivors were determined. The lysozyme activity was increased in the majority of the leukemia patients. Urinary lysozyme of a-bomb survivors could not be detected.

UK PubMed Central (United Kingdom)

BackgroundThe use of measurement tools is an essential part of good evidence-based practice; however, physiotherapists (PTs) are not always confident when selecting, administering,...Full Text Available

UK PubMed Central (United Kingdom)

DNA transposons are efficient tools in transgenesis and have therefore become popular in the analysis of the regulatory genome in vertebrates via enhancer trap screens. Here, I discuss recent progress...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

A porous tooling system was selected for the processing of Graphite/PMR-15 Polyimide laminates in thickness up to 3.2 mm. (0.125 inch). This tool system must have a reasonable strength, permeability dimensional stability, and thermal conductivity to accomplish curing at 600 F and 200 psi and 200 psi autoclave temperature and pressure. A permeability measuring apparatus was constructed and permeability vs. casting water level determined to produce tools at three different permeability levels. On these tools, laminates of 5, 11, and 22 plies (.027, .060, and 0.121 inch) were produced and evaluated by ultrasonic, mechanical, and thermal tests to determine the effect of the tool permeability on the cured laminates. All tools produced acceptable laminates at 5 and 11 plies but only the highest permeability produced acceptable clear ultrasonic C-Scans. Recommendations ...

UK PubMed Central (United Kingdom)

BackgroundMicroarray data are often used for patient classification and gene selection. An appropriate tool for end users and biomedical researchers should combine user friendliness...Full Text Available

Science.gov (United States)

IAQ Tools for Schools Program Leaders in Improving Indoor Air Quality in Schools Baldwin Union Free School District, Baldwin, NY El Paso Independent School District, El Paso,...

International Nuclear Information System (INIS)

The tool materials durability problem, in particular shock and wear resistance, has allowed to formulate a set of requirements and also to stablish the dependence between physical properties and wear. However, for understanding the nature of the process, for example determining the tribological property of the cutting tool, it is necessary to consider the atom interactions in a crystal. A theoretical study of the physical properties of cutting tool materials (W-Ti-C) with varying concentration of titanium is presented. Total and partial local electronic density for each atom in such hard solutions were calculated. (nevyjel)

Science.gov (United States)

A Java-language computer program has been written to facilitate mining of data in files in the

International Nuclear Information System (INIS)

... Formosat (Taiwan, China) 2m WorldView-1 (US) 0.5m The SIAU is using

Science.gov (United States)

... While some measures were suggested as counseling tools to guide and influence ... it be awarded as part of the NCO Evaluation Report (NCOER). ...

International Nuclear Information System (INIS)

The paper demonstrates an application of advanced decision support tools within the framework of the environmental information system of the Province of Milan. These tools include environmental simulation models, multi criteria analysis, risk analysis and environmental accounting for marketable emission permits. After describing the general structure of the system, three demonstrational case studies are introduced concerning: groundwater pollution management; atmospheric pollution management; urban environmental quality perception and management. In the conclusion, potential use of tools like the ones implemented by the province of Milan within the framework of Local Agenda 21 processes is recalled.

Science.gov (United States)

The progress in the development of a surface analysis tool based on the excitation of characteristic

Energy Technology Data Exchange (ETDEWEB)

The fabrication of a Prototype 275/sup 0/C Geothermal Temperature Tool is reviewed. This tool fabrication uses hybrid circuits that were developed at Sandia National Laboratories and are now being built at Teledyne Philbrick. To achieve high-temperature operation, the standard military specification hybrid technology was modified in fabrication processes and materials.

UK PubMed Central (United Kingdom)

TRF-CUT, an ARB-implemented tool, was developed to predict in silico the terminal restriction fragments of aligned small-subunit rRNA gene or functional gene sequences. Application of this new tool...Full Text Available

Science.gov (United States)

The quasi-static normal indentation of sandwich panels with quasi-isotropic laminated composite skins and honeycomb or foam cores, by spherical indentors, has been investigated using experiments and finite element analysis. The experimental program emphasized the effects of indentor size on the resulting load indentation responses, failure mechanisms in the skin and the core, and the measurement of contact areas between indentor and the target. The sandwich panels were indented up to the initiation of skin fracture and the resulting contact data was used to characterize contact power laws. A non-linear finite element model was developed based on the experimental observations to systematically explore the indentation behavior of diverse sandwich configurations and to investigate the contact pressure distributions. The finite element model was used as an experimental tool in the development of a simple non-dimensional semi-empirical model that ...

British Library Electronic Table of Contents (United Kingdom)

This work is focused on effect of various cooling strategies on surface roughness and tool wear during computer aided milling of soft workpiece materials. These milling operations were selected as dry milling, cool air cooling milling and fluid cooling milling. A cool air cooling system was designed and produced to cool end milling tools. Cool air was produced by a vortex tube. Annealed AISI 1050 was used as the workpiece material and cutting tool material was selected as HSS-Co8 DIN 844/BN. Optimal cutting parameters were selected according to workpiece hardness from reference catalog and kept for all tests. Tool wear and surface quality were measured for three different cooling types changing from ten minute machining time to thirty minute machining time. As a result, the surface roughne...

British Library Electronic Table of Contents (United Kingdom)

Fires and explosions have been identified as major potential hazards for Oil and Gas Floating Production Storage Offloading (FPSO) installations and pose risk to personnel, assets, and the environment. Current fire and explosion assessment (FEA) tools require physical effect modeling software and follows standards from API, ISO, and engineering practices. However, the tools are not specific to any particular system such as an FPSO, and do not provide comprehensive guidance for safety engineers to perform FEA. This paper discusses the development of a screening and comparison tool for FEA on FPSOs and the incorporation of an expert system into the tool. The results are computerized using MS Excel/VBA to provide a structured and comprehensive assessment on each equipment and module handling ...

CERN Document Server

A large hadron machine like the LHC with its high track multiplicities always asks for powerful tools that drastically reduce the large background while selecting signal events efficiently. Actually such tools are widely needed and used in all parts of particle physics. Regarding the huge amount of data that will be produced at the LHC, the process of training as well as the process of applying these tools to data, must be time efficient. Such tools can be multivariate analysis -- also called data mining -- tools. In this contribution we present the results for the application of the multivariate analysis, rule growing algorithm RIPPER on a problem of particle selection. It turns out that the meta-methods bagging and cost-sensitivity are essential for the quality of the outcome. The results are compared to other multivariate analysis techniques.

UK PubMed Central (United Kingdom)

To capitalize on the response of tumor cells to ionizing radiation, we developed a controlled-release nanoparticle drug delivery system using a targeting peptide that recognizes a radiation-induced...Full Text Available

UK PubMed Central (United Kingdom)

The technology of gene targeting through homologous recombination has been extremely useful for elucidating gene functions in mice. The application of this technology was thought impossible in the large...Full Text Available

Science.gov (United States)

... detected (and reported) as a by-product of MRM screening (MS/MS) targeted by Law or Rule ... detected (and reported) as a by-product of MRM screening (MS/MS) targeted by Law or Rule ...

UK PubMed Central (United Kingdom)

Many genetic processes depend on proteins interacting with specific sequences on DNA. Despite the large excess of nonspecific DNA in the cell, proteins can locate their targets rapidly. After initial...Full Text Available

UK PubMed Central (United Kingdom)

Considering accessibility of the 3′UTR is believed to increase the precision of microRNA target predictions. We show that, contrary to common belief, ranking by the hybridization energy or by...Full Text Available

UK PubMed Central (United Kingdom)

Operant conditioning techniques were applied to the study of how target fixations are controlled by the probability of signal occurrence. In a standard vigilance setting, gaze at three illuminable...Full Text Available

UK PubMed Central (United Kingdom)

Purposes1. To determine the optimal pelvic nodal clinical target volume for post-operative treatment of endometrial cancer. 2. To compare the DVH of different treatment planning...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

A new rapid solidification process machine will be able to produce eight-inch diameter by six-inch thick finished cavities at the rate of one per hour - a rate that will change the tooling industry dramatically. Global Metal Technologies, Inc. (GMTI) (Solon, OH) has signed an exclusive license with Idaho National Engineered and Environmental Laboratories (INEEL) (Idaho Falls, ID) for the development and commercialization of the rapid solidification process (RSP tooling). The first production machine is scheduled for delivery in July 2001. The RSP tooling process is a method of producing production level tooling in prototype timing. The process' inventor, Kevin McHugh, describes it as a rapid solidification method, which differentiates it from the standard spray forming methods. RSP itself is relatively straightforward. Molten metal is sprayed against the ceramic pattern, replicating the ...

Science.gov (United States)

College student persistence and dropout have been studied for decades, but little inquiry has focused on community college or private two-year college students. Although about half of first-time postsecondary students enroll in a two-year college, researchers understand little about why only approximately a quarter of these degree-seekers complete any degree five years after entrance (Rosenbaum, Deil-Amen, & Person, 2006). Models that exist have been generated primarily from research on residential, four-year college students. The present analysis uses rich qualitative data to excavate the potential of Tinto's Theory of Student Departure for understanding the dynamics of persistence for a more nontraditional group--two-year college commuting students. To better reflect how these students successfully cultivate feelings of belonging and competence, reinforce goal commitment, and access valuable social capital, a new conceptual fusion of the formerly distinct ...

Science.gov (United States)

Sperm competition occurs when a female copulates with two or more males and the sperm of those males compete within the female's reproductive tract to fertilize her eggs. The frequent occurrence of sperm competition has forced males of many species to develop different strategies to overcome the sperm of competing males. A prevalent strategy is for males to increase their sperm investment (total number of sperm allocated by a male to a particular female) after detecting a risk of sperm competition. It has been shown that the proportion of sperm that one male contributes to the sperm pool of a female is correlated with the proportion of offspring sired by that male. Therefore, by increasing his sperm investment a male may bias a potential sperm competition in his favour. Here we show that male meadow voles, Microtus pennsylvanicus, increase their sperm investment when they mate in the presence of another male's odours. Such an increase in sperm ...

International Nuclear Information System (INIS)

Human resource competence building and continued enhancement of performance is the most vital input for safe and reliable operations of a Nuclear Power Plant. Integrated planning leading to the decision of timely selection of optimum number of fresh people and deployment of experienced manpower with desired lead time is inevitable to achieve the above objective. For safe and reliable plant operation human performance analysis followed by suggestive measures to improve the same is needed. Corrective or strengthening input may be in terms of training, work environment, motivations, organizational culture and climate, leadership and prevailing environmental force and bio-rhythm of individuals with critical days are to be worked out The adequacy in training and development not only gives safe and reliable plant operations but results in greater employee satisfaction and self esteem as well. As of date, in the present vibrant global scenario, only the organization which ...

Science.gov (United States)

... they assisted in the 2000 attack on the USS Cole? ... List the types of targets that ETA has attacked. ... was at least partially responsible for the attack. ...

Science.gov (United States)

... 1981. Retention of diphenyls, terphenyls, phenylalkanes and fluorene on graphitized thermal carbon black. Chromatographia 14:510-514. ...

Energy Technology Data Exchange (ETDEWEB)

The production of polarized negative ion beams by collisional pumping is described. Collisional pumping utilizes repeated charge changing collisions in a thick electron-spin-polarized gas or vapor target to form a polarized fast atom beam. The polarized fast atom beam is then partially converted into a polarized negative ion beam in a vapor target. Analysis is presented for a hydrogen beam passing through either a thick polarized H atom target or a thick polarized alkali target. Large polarizations and large currents may be possible.

International Nuclear Information System (INIS)

... carrier-free isotopes chemical preparation gamma spectra isotope production

International Nuclear Information System (INIS)

... range krypton 86 reactions molybdenum 92 target probability quasi-elastic

Science.gov (United States)

The ELXS concept is a novel, portable, micro-instrument targeted for the detection of mineralogic

International Nuclear Information System (INIS)

This paper present the results of a series of calculations made to determine the "2"3"8Pu production potential of several advanced target assembly designs in the Fast Flux Test Facility (FFTF). These calculations show that by using advanced target designs the intimately mix the "2"3"7Np target material with an yttrium hydride moderator, the FFTF has the potential of producing up to 30 kg of high-quality "2"3"8Pu per year.

Energy Technology Data Exchange (ETDEWEB)

This paper describes the phenomenology of nuclear explosions and technologies for their detection as relevant to On-Site Inspection (OSI) for a comprehensive test-ban (CTB). Our experience with the US nuclear test program which has been primarily carried out at the Nevada Test Site (NTS) and in the Pacific Ocean. The goals of OSI are to resolve ambiguous events, reduce uncertainty, deter attempts at evasion, and provide responsive and technically competent means of confirming the occurrence of a nuclear explosion should deterrence fail. These goals would include finding evidence of an evasive nuclear explosion or evidence that the event was non-nuclear, such as an earthquake or large chemical explosion.

CERN Document Server

In this study we consider relations between companies in Poland taking into account common branches they belong to. It is clear that companies belonging to the same branch compete for similar customers, so the market induces correlations between them. On the other hand two branches can be related by companies acting in both of them. To remove weak, accidental links we shall use a concept of threshold filtering for weighted networks where a link weight corresponds to a number of existing connections (common companies or branches) between a pair of nodes.

Energy Technology Data Exchange (ETDEWEB)

A 1976 decision of the US Supreme Court made it clear that the Federal Energy Regulatory Commission (then the Federal Power Commission) has a responsibility to consider and determine allegations that proposed wholesale electric rates create a price squeeze against customers who compete with the wholesaler in making retail electric sales. This article reviews how the commission has approached the matter of discharging its newly recognized responsibility since that time, and describes its current position regarding the several issues and questions that price squeeze allegations raise. 35 references.

Energy Technology Data Exchange (ETDEWEB)

Primary design criterion for this division`s education activities is directly related to meeting the goal of environmental compliance on an accelerated basis and cleanup of the 1989 inventory of inactive sites and facilities by the year 2019. Therefore, the division`s efforts are directed toward stimulating knowledge and capability to achieve the goals while contributing to DOE`s overall goal of increasing scientific, mathematical, and technical literacy and competency. This annual report is divided into: overview, workforce development, academic partnerships, scholarships/fellowships, environmental restoration and waste management employment program, community colleges, outreach, evaluation, and principal DOE contacts.

British Library Electronic Table of Contents (United Kingdom)

This paper develops a model of nonlinear pricing with competition. The novel element is that each consumer's willingness to pay for quality is private information and is allowed to differ across brands. The consumer's preferences are represented by a multidimensional type containing the marginal value of quality for different products. Buyers with high willingness to pay for quality also display strong preferences for particular brands, and require higher discounts in order to switch away from their favorite product. Therefore, competition is fiercer for buyers with lower tastes for quality, and hence more elastic demands. This is in sharp contrast to earlier models in which competition is fiercer for higher-taste, more valuable buyers. In equilibrium, firms either compete intensively for ...

Energy Technology Data Exchange (ETDEWEB)

The production of process heat for agriculture and industry is one of the applications of solar energy which is very close to economic competitivity. Solar collectors can be produced at a reasonable cost by existing industries and are used optimally through applications which present a good time correlation between energy needs and the possible production of solar heat. This article studies heat consumption in industrial and agricultural sectors, gives hints on collectors choices, rates the different projects by simulation taking into account the nature of agricultural and industrial activities and the geographical location of the projects, examines when the equipment first competes according to hypotheses made on the various energy and collectors cost.

Energy Technology Data Exchange (ETDEWEB)

The gastrin releasing peptide (GRP) receptor is becoming an increasingly attractive target for development of new radiolabeled peptides with diagnostic and therapeutic potential. The attractiveness of the GRP receptor as a target is based upon the functional expression of GRP receptors in several tumors of neuroendocrine origin including prostate, breast, and small cell lung cancer. This concise review outlines some of the efforts currently underway to develop new GRP receptor specific radiopharmaceuticals by employing a variety of radiometal chelation systems.

International Nuclear Information System (INIS)

In order to facilitate observations of low energy nuclear reactions, a new type recoil mass-separator together with a new gas-jet target system is being developed at the tandem accelerator facility in Kyushu University. The expected mass-resolving power of the separator is 220 for a solid angle of 10 msr and the practical thickness of the gas-jet target will exceed 0.1 atm#centre dot#cm for the light elements of H and He. (author).

Energy Technology Data Exchange (ETDEWEB)

A 16 l liquid parahydrogen target has been developed for a measurement of the parity-violating {gamma}-asymmetry in the capture of polarized cold neutrons on protons in the {rvec n} + p {yields} d + {gamma} reaction by the NPDGamma collaboration. The target system was carefully designed to meet the stringent requirements on systematic effects for the experiment and also to satisfy hydrogen safety requirements. The target was designed to preserve the neutron polarization during neutron scattering on liquid hydrogen (LH{sub 2}), optimize the statistical sensitivity to the {rvec n} + p {yields} d + {gamma} reaction, minimize backgrounds coming from neutron interaction with the beam windows of the target cryostat, minimize LH{sub 2} density fluctuations which can introduce extra noise in the gamma asymmetry signal, and control systematic effects. The target incorporates two mechanical ...

Energy Technology Data Exchange (ETDEWEB)

In rat adipocyte membranes, both beta-adrenergic agonists and beta-adrenergic antagonists competed with (--)(/sup 3/H)dihydroalprenolol for high affinity (KD 2-4 nM) and low capacity binding sites. The antagonists but not the agonists competed with (--)(/sup 3/H)dihydroalprenolol for lower affinity and higher capacity sites. The present studies were performed in order to characterize the adipocyte beta-adrenergic receptor and distinguish it from low affinity, higher capacity sites which were heat-labile and not stereoselective. When isoproterenol was used to define the nonspecific binding, saturation studies showed a single binding site with a capacity of approximately 100 fmol/mg membrane protein (corresponding to approximately 50,000 sites/adipocyte). Binding was saturated by 10 nM (--)(/sup 3/H)dihydroalprenolol. Approximate KD's of 204 nM were observed. Kinetic analysis of (--)(/sup 3/H)dihydroalprenolol binding provided an ...

Energy Technology Data Exchange (ETDEWEB)

{sup 14}C-Sugar uptake and incorporation into starch by slices of developing maize (Zea mays L.) endosperm were examined and compared with sugar uptake by maize endosperm-derived suspension cultures. Rates of sucrose, fructose, and D- and L-glucose uptake by slices were similar, whereas uptake rates for these sugars differed greatly in suspension cultures. Concentration dependence of sucrose, fructose, and D-glucose uptake was biphasic (consisting of linear plus saturable components) with suspension cultures but linear with slices. These and other differences suggest that endosperm slices are freely permeable to sugars. After diffusion into the slices, sugars were metabolized and incorporated into starch. Starch synthesis, but not sugar accumulation, was greatly reduced by 2.5 millimolar p-chloromercuribenzenesulfonic acid and 0.1 millimolar carbonyl cyanide m-chlorophenylhydrazone. Starch synthesis was dependent on kernel age and incubation temperature, but not on external pH (5 ...

British Library Electronic Table of Contents (United Kingdom)

Certain allelochemicals of the marine dinoflagellate Alexandrium tamarense cause lysis of a broad spectrum of target protist cells but the lytic mechanism is poorly defined. We first hypothesized that membrane sterols serve as molecular targets of these lytic compounds, and that differences in sterol composition among donor and target cells may cause insensitivity of Alexandrium and sensitivity of targets to lytic compounds. We investigated Ca^2^+ influx after application of lytic fractions to a model cell line PC12 derived from a pheochromocytoma of the rat adrenal medulla to establish how the lytic compounds affect ion flux associated with lysis of target membranes. The lytic compounds increased permeability of the cell membrane for Ca^2^+ ions even during blockade of Ca^2^+ channels wit...

International Nuclear Information System (INIS)

The modeling methods used to compute the neutron-induced activation of target and near-target materials in the NIF facility are presented. A detailed space and energy description of the neutron environment in the different materials is provided. A new capability has been developed to treat in a general way the activation of debris produced in an operational regime of yield and no-yield experiments. First calculations are addressed to analyze the activity of the debris into the target chamber. The contribution of the different components to activity, interior dose rates, and waste disposal rating (WDR) is determined. The importance of the activation coming from primary irradiation in the target, and from secondary irradiation in debris deposited onto the first wall is assessed. Finally, waste hazards of the activated debris when removed out of the chamber and stored are analyzed. (authors)

Energy Technology Data Exchange (ETDEWEB)

In the Fourth Dutch National Environmental Outlook (NMP, abbreviated in Dutch) of the National Institute of Public Health and the Environment (VROM), published in July 1997, possible future developments in the traffic and transport sector in the Netherlands are described for the period 1995-2020 and also evaluates present Dutch policies. NMP-4 also offers possible solutions for expected environmental problems. This report serves as a background document for the traffic and transport sector. With a view to present Dutch policies, the main conclusions drawn from the Outlook are that: (1) the policy targets for car and lorry use for 2010 will not be met, (2) the target for CO2 emissions from road transport for 2010 will not be met, (3) the NOx emission target for 2010 will be met for cars, but not for trucks, (4) the VOC emission target for 2010 will be met for cars, but not for trucks, and (5) the noise ...

Energy Technology Data Exchange (ETDEWEB)

The Energy Nomographs are a quick, simple-to-use tool for designing energy conscious lighting systems. Many assumptions and simplifications have been incorporated in the tool which may decrease its accuracy. However, the tool is accurate enough for use in Schematic Design, where design decisions have the largest impact on end energy use. It is not intended to replace all other energy design tools but rather supplement them when quicker decisions must be made. An important aspect of this analysis technique is its graphic procedural quality. As each design decision is made in the course of completing the nomograph procedure, the effects of each may be seen graphically and alternatives chosen without having to complete the entire process. This will have time but, more important, will act as an educational tool to the designer. As more calculations are completed, the user realizes how ...

International Nuclear Information System (INIS)

The possibility of surface modification of high-speed steel cutting tool by means of vacuum-plasma treatment including ion nitriding in gas plasma followed by the deposition of wear resistant (Ti, Al)N coatings in metal-gas plasma of a vacuum arc discharge is studied. The regularities of nitrided layer formation and the structure of these layers under various operation conditions of cutting tool are investigated. Optimum conditions of vacuum-plasma treatment providing the best wear resistance of cutting are determined

International Nuclear Information System (INIS)

We have used scale models to measure the predicted coupling of electromagnetic fields simulating the effects of high-altitude nuclear electromagnetic pulses (HEMP) on the interior surfaces of electronic components. Predictive tools for exterior coupling are adequate. For interior coupling, however, such tools are in their infancy. Our methodological approach combines analytical, computational, and laboratory techniques in a complementary way to take advantage of their separate strengths. Computer models are a promising tool, as they can be used to treat complex objects with arbitrary shapes, dielectrics, and cables, and multiple apertures. Laboratory tests can expand the domain of investigation even further.

Science.gov (United States)

Systems MEMS sensors C11-20 Lifetime Distributions of Aluminum Electrolytic Capacitors C11-22 Adhesion Strength of Advanced Polymer Films for Flexible and Rigid...

UK PubMed Central (United Kingdom)

BackgroundOver the past decade, many investigators have used sophisticated time series tools for the analysis of genomic sequences. Specifically, the correlation of the nucleotide...Full Text Available

UK PubMed Central (United Kingdom)

The product-operator formalism is the most commonly used tool for describing and designing multidimensional NMR experiments. In spite of its relative simplicity and sound theoretical underpinnings,...Full Text Available

Science.gov (United States)

... Missionaries and cannibals [MaC] (Newell, McDermott and Forgy, 1977, p. 63): Three missionaries and three cannibals must cross a river in a two ...

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monitoring of open pit mining operations. INTRODUCTION. Aerial photography has long been a useful tool for geologists. Cameras ...

UK PubMed Central (United Kingdom)

BackgroundHealth service databases of administrative type can be a useful tool for the study of progression of a disease, but the data reported in such sources could be affected...Full Text Available

UK PubMed Central (United Kingdom)

Percutaneous renal biopsy (PRB) is a safe and effective tool in the diagnosis and management of renal disease. It is the gold standard for evaluating renal parenchymal disease. It is both useful for...Full Text Available

Energy Technology Data Exchange (ETDEWEB)

In this paper information about monograph construction is provided and some sample nomographs constructed by the author are included to encourage the use of these tools in operational health physics applications.

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602-906-5555 Important Links Electronic Reading Room HazMat Mgrs Tools Satellite Network Security Procedures Staff Directory Links - Partners Restricted access BLM NTC INTRANET...

UK PubMed Central (United Kingdom)

BACKGROUNDNew diagnostic tools are urgently needed to interrupt the transmission of tuberculosis and multidrug-resistant tuberculosis. Rapid,...Full Text Available

Science.gov (United States)

The introduction of numerical control (NC) machine tools has made it possible to automate machining in series and small series production. The organization of automated production sections merged NC machine tools with automated transport systems. However, both the one and the other require the presence of an operative at the machine for low skilled operations. Industrial robots perform a number of auxiliary operations, such as equipment loading-unloading and control, changing cutting and auxiliary tools, controlling workpieces and parts, and cleaning of location surfaces. When used with a group of equipment they perform transfer operations between the machine tools. Industrial robots eliminate the need for workers to form auxiliary operations. This underscores the importance of developing robotized manufacturing centers providing for minimal human participation in production and creating conditions for ...

Science.gov (United States)

Possible ICE Tools Relationship. within a Business Model ... Established a Joint IV&V Cost Estimating (ICE) Team comprised of Personnel from NASA, ...

Science.gov (United States)

Mar 15, 2011 ... The NASA/JPL Education Office works with educators -- both classroom teachers and informal educators -- to provide tools, resources and ...

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Sep 18, 2009 ... It is proposed to develop desensitized optimal filtering ... in robust and/or adaptive generalized Kalman and Sigma-Point filters for ...

UK PubMed Central (United Kingdom)

BackgroundNucleotide sequences and the gene arrangements of mitochondrial genomes are effective tools for resolving phylogenetic problems. Hemipteroid insects are known to possess...Full Text Available

UK PubMed Central (United Kingdom)

INTRODUCTIONInformatics and automation are important tools for the reduction of work, errors and costs in a hospital pharmacy.OBJECTIVESTo describe...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundAdequate pain assessment is critical for evaluating the efficacy of analgesic treatment in clinical practice and during the development of new therapies. Yet the currently...Full Text Available

Science.gov (United States)

R. J. Schwinghamer: Magnetic Forming in Space,. Astronautics, September 1962, pp . 63-67. Burkhalter & White: New Tools for the Inquisitive ...

International Nuclear Information System (INIS)

The production methods for seven radioisotopes, Ga-67, Sr-85, Pd-103, In-111, Tu-167, Hg-197 and Pb-203, by using a classical 1.5m cyclotron in the Institute of Physics and Power Engineering, Obninsk, USSR, are described. At present, more than 50 cyclotrons in different countries are used for the production of radioisotopes applied to medicine. Radioisotopes are produced with the cyclotron in the I.Ph.P.E. in the form of irradiated targets, which are delivered to Moscow radiopharmaceutical factory, where radiopharmaceuticals are produced on the base of these targets. The cyclotron is operated in two regimes providing the acceleration of protons, deuterons and alpha -particles. Two types of target assemblies are used for irradiation, the one is intended for the internal beam, and the other is for the external beam. The reactions used for the production of seven radioisotopes described above, the types of ...

Science.gov (United States)

This paper proposes a new pattern recognition system employing optical joint transform correlation (JTC) technique which offers a great number of advantages over similar digital techniques, including very fast operation, simple architecture and capability of updating the reference image in real time. The proposed JTC technique incorporates a synthetic discriminant function (SDF) of the target image estimated from different training images to make the pattern recognition performance invariant to noise and distortion. It then involves four different phase-shifted versions of the same target SDF reference image, which are individually joint transform correlated with the given input scene. When the correlation signals are combined, it produces a single cross-correlation peak corresponding to each potential target present in the given input scene. The proposed technique also includes a fringe-adjusted filter to generate a ...

CERN Document Server

The HARP experiment at CERN is performing extensive measurements of hadron production cross sections and secondary particle yields, in the momentum range 1.5-15 GeV/c, over the full solid angle and using a large set of cryogenic and solid targets. First measurements of hadron production cross-sections in the forward region are reported using an aluminium target 5% of an interaction length thick and a proton beam of 12.9 GeV/c. A preliminary analysis in the large angle region of elastic scattering events produced with the cryogenic hydrogen target at 3 GeV/c beam momentum is also presented.

International Nuclear Information System (INIS)

Carrier-free radioisotopes of tungsten, "1"7"6","1"7"7W, and their corresponding daughter radionuclides "1"7"6","1"7"7Ta, have been produced in holmium target by heavy ion activation with "1"6O"5"+ beam. An attempt has been made to separate these carrier-free radionuclides from bulk holmium target through LLX using cation exchanger HDEHP. (author)

International Nuclear Information System (INIS)

A simple highly efficient procedure has been developed for recovery of thallium radioisotopes from lead and bismuth targets irradiated by 1-GeV protons. The procedure is based on the use of extraction chromatography. The cross-sections have been determined for formation of "2"0"0Pb, "2"0"1Pb, "2"0"2"mPb, and "2"0"3Pb radioisotopes in targets from lead with natural isotopic composition, irradiated by 1-GeV protons.

British Library Electronic Table of Contents (United Kingdom)

A modified variable structure interacting multiple model (M-VSIMM) estimator for complex hybrid maneuver target tracking is presented. The M-VSIMM could potentially be applied to fire control systems (FCS) used on warships. Target model groups were designed using 3D dimensional dynamic target models. Optimal model group selection logic was proposed, contrary to the activation and termination logic in the original VSIMM. The system will respond faster with optimal model group selection logic. After performing simulations, the tracking performances of the Kalman, ?-?(-?), VDIE, IMM and M-VSIMM filters were compared under various maneuvering conditions.

Energy Technology Data Exchange (ETDEWEB)

The velocity distribution of electrons ejected close to the forward direction by 0.8-2 MeV/A ions traversing various solid targets, including a Au monocrystal, is measured in coincidence with emerging charge-selected ions. The velocity spectrum is observed to be independent of outgoing projectile velocity and charge state for polycrystalline targets. Measurements on the Au crystal under channeling conditions show dependences on final charge state, and are tentatively explained by assuming that the main contribution to the production yield comes from the non-channeled fraction of the ions. A simple model for the creation of the forward-ejected electrons is proposed, which accounts for most of the experimental findings.

Energy Technology Data Exchange (ETDEWEB)

The centroid and envelope dynamics of a high-intensity charged particle beam are investigated as a beam smoothing technique to achieve uniform illumination over a suitably chosen region of the target for applications to ion-beam-driven high energy density physics and heavy ion fusion. The motion of the beam centroid projected onto the target follows a smooth pattern to achieve the desired illumination, for improved stability properties during the beam-target interaction. The centroid dynamics is controlled by an oscillating "wobbler", a set of electrically-biased plates driven by RF voltage. __________________________________________________

Energy Technology Data Exchange (ETDEWEB)

A new commercial cutting tool software package replaced an internally created legacy system. This report describes the issues that surfaced during the migration and installation of the commercial package and the solutions employed. The primary issues discussed are restructuring the data between two drastically different database schemas and the creation of individual component graphics.

Energy Technology Data Exchange (ETDEWEB)

A 1000-watt CO/sub 2/ laser has been demonstrated as a reliable production machine tool for cutting of plastics, high strength reinforced composites, and other nonmetals. More than 40 different plastics have been laser cut, and the results are tabulated. Applications for laser cutting described include fiberglass-reinforced laminates, Kevlar/epoxy composites, fiberglass-reinforced phenolics, nylon/epoxy laminates, ceramics, and disposable tooling made from acrylic.

Energy Technology Data Exchange (ETDEWEB)

The device is made by a tool at the end of a flexible cable, a motor for the rotation of the flexible, a linear drive with a guide for it between the winder and the tube.

British Library Electronic Table of Contents (United Kingdom)

The mechanisms underlying life machinery are still not completely understood. Something is known, something is ?probably? known, other things are still unknown. Scientists all over the world are working very hard to clarify the processes regulating the cell life cycle and bioinformaticians try to support them by developing specialized automated tools. Within the plethora of applications devoted to the study of life mechanisms, tools for the analysis and comparison of biological networks are catching the attention of many researchers. It is interesting to investigate why.

Science.gov (United States)

The C isotopic composition of CH4 emissions are strongly influenced by the pathway of CH4 formation. Contrary to data from other freshwater systems, soil gas and surface flux measurements made in the tropical rain forests of Puerto Rico strongly suggest that CH4 produced in these environments was derived from CO2 reduction, rather than from acetate consumption. This study explored the effects of bacterial competition for acetate, pH, and soil structure on the pathways of CH4 formation in tropical rain forest soils. Our goal was to test two principal hypotheses: (1) ferric iron-reducing bacteria out-competed methanogens for acetate, resulting in greater CO2 reduction rather than aceticlastic methanogenesis, and (2) the low pH of tropical rain forest soils favors CO2 reduction rather than aceticlastic methanogenesis. In addition, this study also investigated the effect of destroying soil aggregate structure on the pathways and rates of CH4 production. Ferric ...

UK PubMed Central (United Kingdom)

Understanding the physical characteristics of the local microenvironment in which Mycobacterium tuberculosis resides is an important goal that may allow the targeting of metabolic processes...Full Text Available

International Nuclear Information System (INIS)

Several different aspects of the influence of the target backing on in-beam electron spectra following compound nuclear reactions induced by accelerated ions at tandem energies irradiating backed targets are discussed in detail. This discussion is illustrated by a few typical examples, such as "1"2C"5"+ and "3"1P"1"0"+ beams at 4 MeV/u bombarding Sn(+Be), Sn(+Au), Pb(+C) backed targets. Moreover, the relative influence of electron backscattering, electron Doppler shift and Doppler broadening as well as #delta#-electron emission on the low energy electron spectra (E_e#<=#100 keV) obtained under such conditions are investigated in the frame of the available experimental data. (orig.).

UK PubMed Central (United Kingdom)

Axon outgrowth and guidance to the proper target requires the coordination of filamentous (F)-actin and microtubules (MTs), the dynamic cytoskeletal polymers that promote shape change and locomotion....Full Text Available

Energy Technology Data Exchange (ETDEWEB)

We develop a systematic framework for studying target space duality at the classical level. We show that target space duality between manifolds M and M-tilde arises because of the existence of a very special symplectic manifold. This manifold locally looks like MxM-tilde and admits a double fibration. We analyze the local geometric requirements necessary for target space duality and prove that both manifolds must admit flat orthogonal connections. We show how abelian duality, nonabelian duality and Poisson-Lie duality are all special cases of a more general framework. As an example we exhibit new (nonlinear) dualities in the case M=M-tilde=R{sup n}.

UK PubMed Central (United Kingdom)

The oviduct is an exquisitely designed organ that functions in picking-up ovulated oocytes, transporting gametes in opposite directions to the site of fertilization, providing a suitable environment...Full Text Available

UK PubMed Central (United Kingdom)

The success of monoclonal antibodies in clinical practice is dependent on good design. Finding a suitable target is the most important part as other properties of the antibody can be altered by genetic...Full Text Available

Science.gov (United States)

... TARGET SENSOR-MK 80 SERIES BOMBS ... 5-inch-, and 2.75-inch- diameter rocket motors that ... balance when compared to incoming solar radiation ...

Science.gov (United States)

Nov 21, 2003... for the European Space Agency's Automated Transport Vehicle, a new, uncrewed station cargo vehicle targeted for launch late next year. ...

UK PubMed Central (United Kingdom)

PurposeClinical trials have commenced to evaluate the feasibility of targeting malignant gliomas with genetically engineered cytolytic T-cells (CTLs) delivered directly...Full Text Available

UK PubMed Central (United Kingdom)

In animal models, single-gene mutations in genes involved in insulin/IGF and target of rapamycin signalling pathways extend lifespan to a considerable extent. The genetic, genomic and epigenetic influences...Full Text Available

UK PubMed Central (United Kingdom)

An application that provides a flexible and easy to use interface to the GAMMA spectral simulation package is described that is targeted at investigations using in vivo MR spectroscopic methods....Full Text Available

UK PubMed Central (United Kingdom)

This letter reports a study designed to measure the benefits of voicing in the recognition of concurrent syllables. The target and distracter syllables were either voiced or whispered, producing...Full Text Available

Science.gov (United States)

... defense's weapons are Space-based kinetic-kill vehicles ... I ti I obtained by dividing the weapons as ... of the optimal weapon-arge assigntments and ...

UK PubMed Central (United Kingdom)

The biosynthesis of insect juvenile hormone (JH) and its neuroendocrine control are attractive targets for chemical control of insect pests and vectors of disease. To facilitate the molecular...Full Text Available

UK PubMed Central (United Kingdom)

BackgroundThe metagenomic analysis of microbial communities holds the potential to improve our understanding of the role of microbes in clinical conditions. Recent, dramatic improvements...Full Text Available

Science.gov (United States)

... used to track a point source target ... A one sigma tracking error of .2 ... LOOKING INFRARED SYSTEMS, *KALMAN FILTERING, SIGNAL PROCESSING ...

Energy Technology Data Exchange (ETDEWEB)

Two refrains heard in the current retail wheeling debate are that a restructuring of the electric utility industry is inevitable and that its consequences are unpredictable. Notwithstanding the benefits of open competition, there are specific disadvantages of unlimited retail wheeling for some existing independent facilities and especially for hydropower plants. A capital-intensive industry, hydropower is not well-postured to compete effectively in the short-term, against new technologies and fuel sources available in the current marketplace. Hydropower is flat out non-competitive on a price basis with available new capacity. Unless hydro is afforded the same government supports offered to other renewable energy sources, only municipal plants with access to subsidized financing rates and pumped storage plants are going to be built.

CERN Document Server

In this work, we aim to gain a better understanding of the volatility smile observed in options markets through microsimulation (MS). We adopt two types of active traders in our MS model: speculators and arbitrageurs, and call and put options on one underlying asset. Speculators make decisions based on their expectations of the asset price at the option expiration time. Arbitrageurs trade at different arbitrage opportunities such as violation of put-call parity. Difference in liquidity among options is also included. Notwithstanding its simplicity, our model can generate implied volatility (IV) curves similar to empirical observations. Our results suggest that the volatility smile is related to the competing effect of heterogeneous trading behavior and the impact of differential liquidity.

British Library Electronic Table of Contents (United Kingdom)

By means of ab-initio electronic structure calculation and one-dimensional Boltzmann transport equation solution, we investigate the size dependent thermoelectric (TE) properties of n-type ZnO nanowires (NWs) and surface passivation effects. As demonstrated by our calculations, largest figure of merit ZT achievable in thin NWs is larger than that in wide NWs, whereas being restrained by higher demand of n-type doping. Moreover, bare NWs are superior in TE application comparing with the passivated. To compete with conventional TE materials, lattice thermal conductivity of ZnO NWs should be at least 2 orders of magnitude lower than bulk value.

British Library Electronic Table of Contents (United Kingdom)

While both sperm number and quality are now recognized to be important in determining the outcome of sperm competition, very few studies have experimentally assessed the influence of these two parameters simultaneously. We studied the effect of sperm quality and number on competitive fertilization success in an internal-fertilizing fish, the guppy (Poecilia reticulata), which is characterized by high levels of sperm competition. We artificially inseminated virgin females with varying proportion of sperm from two competing males, while holding constant the total number of sperm transferred to the female. Sperm morphology and sperm swimming velocity were also determined prior to insemination. The paternity outcome of sperm competition trials was assessed through molecular analyses of the res...

British Library Electronic Table of Contents (United Kingdom)

To address the functions of FGFR2 and FGFR3 signaling during mandibular skeletogenesis, we over-expressed in the developing chick mandible, replication-competent retroviruses carrying truncated FGFR2c or FGFR3c that function as dominant negative receptors (RCAS-dnFGFR2 and RCAS-dnFGFR3). Injection of RCAS-dnFGFR3 between HH15 and 20 led to reduced proliferation, increased apoptosis, and decreased differentiation of chondroblasts in Meckel's cartilage. These changes resulted in the formation of a hypoplastic mandibular process and truncated Meckel's cartilage. This treatment also affected the proliferation and survival of osteoprogenitor cells in osteogenic condensations, leading to the absence of five mandibular bones on the injected side. Injection of RCAS-dnFGFR2 between HH15 and 20 or R...